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Sample records for blimps low-cost tools

  1. Miniature Blimps for Surveillance and Collection of Samples

    Science.gov (United States)

    Jones, Jack

    2004-01-01

    Miniature blimps are under development as robots for use in exploring the thick, cold, nitrogen atmosphere of Saturn's moon, Titan. Similar blimps can also be used for surveillance and collection of biochemical samples in buildings, caves, subways, and other, similar structures on Earth. The widely perceived need for means to thwart attacks on buildings and to mitigate the effects of such attacks has prompted consideration of the use of robots. Relative to rover-type (wheeled) robots that have been considered for such uses, miniature blimps offer the advantage of ability to move through the air in any direction and, hence, to perform tasks that are difficult or impossible for wheeled robots, including climbing stairs and looking through windows. In addition, miniature blimps are expected to have greater range and to cost less, relative to wheeled robots.

  2. SUMOylation of Blimp-1 promotes its proteasomal degradation.

    Science.gov (United States)

    Shimshon, Livnat; Michaeli, Avital; Hadar, Rivka; Nutt, Stephen L; David, Yael; Navon, Ami; Waisman, Ari; Tirosh, Boaz

    2011-08-04

    B lymphocyte induced maturation protein-1 (Blimp-1) is a transcription repressor of the Krueppel-like family. Blimp-1 plays important roles in developmental processes, such as of germ cells and hair follicle stem cells. In B lymphocytes Blimp-1 orchestrates the terminal differentiation into plasma cells. We discovered that Blimp-1 undergoes SUMOylation by SUMO-1. This SUMOylation is modulated by the SUMO protease SENP1. While Blimp-1 is relatively stable in 293T cells, a fusion with SUMO1 rendered it to rapid proteasomal degradation. Increase in SENP1 activity stabilized Blimp-1, while a decrease promoted its degradation. Our data indicate that SUMOylation of Blimp-1 regulates its intracellular stability. Copyright © 2011 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

  3. Development of the Research Platform of Small Autonomous Blimp Robot

    Science.gov (United States)

    Takaya, Toshihiko; Kawamura, Hidenori; Yamamoto, Masahito; Ohuchi, Azuma

    A blimp robot is attractive as an small flight robot and can float in the air by buoyancy and realize safe to the crash small flight with low energy and can movement for a long time compared with other flight robots with low energy and can movement for a long time compared with other flight robots. However, control of an airplane robot is difficult for the nonlinear characteristic exposed to inertia by the air flow in response to influence. Therefore, the applied research which carried out the maximum use of such in recent years a blimp robot's feature is prosperous. In this paper, we realized development of blimp robot for research which can be used general-purpose by carrying out clue division of the blimp robot body at a unit, and constituting and building for research of blimp robot, and application development. On the other hand, by developing a general-purpose blimp robot research platform, improvement in the research efficiency of many researchers can be attained, and further, research start of blimp robot becomes easy and contributes to development of research. We performed the experiments for the above-mentioned proof. 1. Checked basic keeping position performance and that various orbital operation was possible. And the unit exchange ease of software unit was checked by the experiment which exchanges the control layer of software for learning control from PID control, and carries out comparison of operation. 2. In order to check the exchange ease of hardware unit, the sensor was exchanged for the microphon from the camera, and control of operation was checked. 3. For the unit addition ease, the microphon which carries out sound detection with the picture detection with a camera was added, and control of operation was verified. 4. The unit exchange was carried out for the check of a function addition and the topological map generation experiment by addition of an ultrasonic sensor was conducted. Developed blimp robot for research mounted the exchange ease

  4. Blimp-1 impairs T cell function via upregulation of TIGIT and PD-1 in patients with acute myeloid leukemia.

    Science.gov (United States)

    Zhu, Liuluan; Kong, Yaxian; Zhang, Jianhong; Claxton, David F; Ehmann, W Christopher; Rybka, Witold B; Palmisiano, Neil D; Wang, Ming; Jia, Bei; Bayerl, Michael; Schell, Todd D; Hohl, Raymond J; Zeng, Hui; Zheng, Hong

    2017-06-19

    T cell immunoglobulin and immunoreceptor tyrosine-based inhibitory motif (ITIM) domain (TIGIT) and programmed cell death protein 1 (PD-1) are important inhibitory receptors that associate with T cell exhaustion in acute myeloid leukemia (AML). In this study, we aimed to determine the underlying transcriptional mechanisms regulating these inhibitory pathways. Specifically, we investigated the role of transcription factor B lymphocyte-induced maturation protein 1 (Blimp-1) in T cell response and transcriptional regulation of TIGIT and PD-1 in AML. Peripheral blood samples collected from patients with AML were used in this study. Blimp-1 expression was examined by flow cytometry. The correlation of Blimp-1 expression to clinical characteristics of AML patients was analyzed. Phenotypic and functional studies of Blimp-1-expressing T cells were performed using flow cytometry-based assays. Luciferase reporter assays and ChIP assays were applied to assess direct binding and transcription activity of Blimp-1. Using siRNA to silence Blimp-1, we further elucidated the regulatory role of Blimp-1 in the TIGIT and PD-1 expression and T cell immune response. Blimp-1 expression is elevated in T cells from AML patients. Consistent with exhaustion, Blimp-1 + T cells upregulate multiple inhibitory receptors including PD-1 and TIGIT. In addition, they are functionally impaired manifested by low cytokine production and decreased cytotoxicity capacity. Importantly, the functional defect is reversed by inhibition of Blimp-1 via siRNA knockdown. Furthermore, Blimp-1 binds to the promoters of PD-1 and TIGIT and positively regulates their expression. Our study demonstrates an important inhibitory effect of Blimp-1 on T cell response in AML; thus, targeting Blimp-1 and its regulated molecules to improve the immune response may provide effective leukemia therapeutics.

  5. Blimp-1 impairs T cell function via upregulation of TIGIT and PD-1 in patients with acute myeloid leukemia

    Directory of Open Access Journals (Sweden)

    Liuluan Zhu

    2017-06-01

    Full Text Available Abstract Background T cell immunoglobulin and immunoreceptor tyrosine-based inhibitory motif (ITIM domain (TIGIT and programmed cell death protein 1 (PD-1 are important inhibitory receptors that associate with T cell exhaustion in acute myeloid leukemia (AML. In this study, we aimed to determine the underlying transcriptional mechanisms regulating these inhibitory pathways. Specifically, we investigated the role of transcription factor B lymphocyte-induced maturation protein 1 (Blimp-1 in T cell response and transcriptional regulation of TIGIT and PD-1 in AML. Methods Peripheral blood samples collected from patients with AML were used in this study. Blimp-1 expression was examined by flow cytometry. The correlation of Blimp-1 expression to clinical characteristics of AML patients was analyzed. Phenotypic and functional studies of Blimp-1-expressing T cells were performed using flow cytometry-based assays. Luciferase reporter assays and ChIP assays were applied to assess direct binding and transcription activity of Blimp-1. Using siRNA to silence Blimp-1, we further elucidated the regulatory role of Blimp-1 in the TIGIT and PD-1 expression and T cell immune response. Results Blimp-1 expression is elevated in T cells from AML patients. Consistent with exhaustion, Blimp-1+ T cells upregulate multiple inhibitory receptors including PD-1 and TIGIT. In addition, they are functionally impaired manifested by low cytokine production and decreased cytotoxicity capacity. Importantly, the functional defect is reversed by inhibition of Blimp-1 via siRNA knockdown. Furthermore, Blimp-1 binds to the promoters of PD-1 and TIGIT and positively regulates their expression. Conclusions Our study demonstrates an important inhibitory effect of Blimp-1 on T cell response in AML; thus, targeting Blimp-1 and its regulated molecules to improve the immune response may provide effective leukemia therapeutics.

  6. Plasma Cell Ontogeny Defined by Quantitative Changes in Blimp-1 Expression

    Science.gov (United States)

    Kallies, Axel; Hasbold, Jhagvaral; Tarlinton, David M.; Dietrich, Wendy; Corcoran, Lynn M.; Hodgkin, Philip D.; Nutt, Stephen L.

    2004-01-01

    Plasma cells comprise a population of terminally differentiated B cells that are dependent on the transcriptional regulator B lymphocyte–induced maturation protein 1 (Blimp-1) for their development. We have introduced a gfp reporter into the Blimp-1 locus and shown that heterozygous mice express the green fluorescent protein in all antibody-secreting cells (ASCs) in vivo and in vitro. In vitro, these cells display considerable heterogeneity in surface phenotype, immunoglobulin secretion rate, and Blimp-1 expression levels. Importantly, analysis of in vivo ASCs induced by immunization reveals a developmental pathway in which increasing levels of Blimp-1 expression define developmental stages of plasma cell differentiation that have many phenotypic and molecular correlates. Thus, maturation from transient plasmablast to long-lived ASCs in bone marrow is predicated on quantitative increases in Blimp-1 expression. PMID:15492122

  7. Multifunctional role of the transcription factor Blimp1 in coordinating plasma cell differentiation

    Science.gov (United States)

    Minnich, Martina; Tagoh, Hiromi; Bönelt, Peter; Axelsson, Elin; Fischer, Maria; Cebolla, Beatriz; Tarakhovsky, Alexander; Nutt, Stephen L.; Jaritz, Markus; Busslinger, Meinrad

    2018-01-01

    Blimp1 is an essential regulator of plasma cells. Here we studied its functions in plasmablast differentiation by identifying regulated Blimp1 target genes. Blimp1 promoted plasmablast migration and adhesion. It repressed several transcription factor genes and Aicda, thus silencing B-cell-specific gene expression, antigen presentation and class switch recombination in plasmablasts. It directly activated genes, leading to increased expression of the plasma cell regulator IRF4 and proteins involved in immunoglobulin secretion. Blimp1 induced immunoglobulin gene transcription by controlling Igh and Igk 3’ enhancers and regulated the posttranscriptional expression switch from the membrane-bound to secreted immunoglobulin heavy-chain by activating Ell2. Notably, Blimp1 recruited chromatin-remodeling and histone-modifying complexes to regulate its target genes. Hence, many essential functions of plasma cells are under Blimp1 control. PMID:26779602

  8. Blimp-1-Dependent IL-10 Production by Tr1 Cells Regulates TNF-Mediated Tissue Pathology.

    Directory of Open Access Journals (Sweden)

    Marcela Montes de Oca

    2016-01-01

    Full Text Available Tumor necrosis factor (TNF is critical for controlling many intracellular infections, but can also contribute to inflammation. It can promote the destruction of important cell populations and trigger dramatic tissue remodeling following establishment of chronic disease. Therefore, a better understanding of TNF regulation is needed to allow pathogen control without causing or exacerbating disease. IL-10 is an important regulatory cytokine with broad activities, including the suppression of inflammation. IL-10 is produced by different immune cells; however, its regulation and function appears to be cell-specific and context-dependent. Recently, IL-10 produced by Th1 (Tr1 cells was shown to protect host tissues from inflammation induced following infection. Here, we identify a novel pathway of TNF regulation by IL-10 from Tr1 cells during parasitic infection. We report elevated Blimp-1 mRNA levels in CD4+ T cells from visceral leishmaniasis (VL patients, and demonstrate IL-12 was essential for Blimp-1 expression and Tr1 cell development in experimental VL. Critically, we show Blimp-1-dependent IL-10 production by Tr1 cells prevents tissue damage caused by IFNγ-dependent TNF production. Therefore, we identify Blimp-1-dependent IL-10 produced by Tr1 cells as a key regulator of TNF-mediated pathology and identify Tr1 cells as potential therapeutic tools to control inflammation.

  9. Blimp-1 controls plasma cell function through regulation of immunoglobulin secretion and the unfolded protein response

    Science.gov (United States)

    Tellier, Julie; Shi, Wei; Minnich, Martina; Liao, Yang; Crawford, Simon; Smyth, Gordon K; Kallies, Axel; Busslinger, Meinrad; Nutt, Stephen L

    2015-01-01

    Plasma cell differentiation requires silencing of B cell transcription, while establishing antibody-secretory function and long-term survival. The transcription factors Blimp-1 and IRF4 are essential for plasma cell generation, however their function in mature plasma cells has remained elusive. We have found that while IRF4 was essential for plasma cell survival, Blimp-1 was dispensable. Blimp-1-deficient plasma cells retained their transcriptional identity, but lost the ability to secrete antibody. Blimp-1 regulated many components of the unfolded protein response (UPR), including XBP-1 and ATF6. The overlap of Blimp-1 and XBP-1 function was restricted to the UPR, with Blimp-1 uniquely regulating mTOR activity and plasma cell size. Thus, Blimp-1 is required for the unique physiological capacity of plasma cells that enables the secretion of protective antibody. PMID:26779600

  10. Role of Blimp-1 in programing Th effector cells into IL-10 producers

    Science.gov (United States)

    Neumann, Christian; Heinrich, Frederik; Neumann, Katrin; Junghans, Victoria; Mashreghi, Mir-Farzin; Ahlers, Jonas; Janke, Marko; Rudolph, Christine; Mockel-Tenbrinck, Nadine; Kühl, Anja A.; Heimesaat, Markus M.; Esser, Charlotte; Im, Sin-Hyeog; Radbruch, Andreas

    2014-01-01

    Secretion of the immunosuppressive cytokine interleukin (IL) 10 by effector T cells is an essential mechanism of self-limitation during infection. However, the transcriptional regulation of IL-10 expression in proinflammatory T helper (Th) 1 cells is insufficiently understood. We report a crucial role for the transcriptional regulator Blimp-1, induced by IL-12 in a STAT4-dependent manner, in controlling IL-10 expression in Th1 cells. Blimp-1 deficiency led to excessive inflammation during Toxoplasma gondii infection with increased mortality. IL-10 production from Th1 cells was strictly dependent on Blimp-1 but was further enhanced by the synergistic function of c-Maf, a transcriptional regulator of IL-10 induced by multiple factors, such as the Notch pathway. We found Blimp-1 expression, which was also broadly induced by IL-27 in effector T cells, to be antagonized by transforming growth factor (TGF) β. While effectively blocking IL-10 production from Th1 cells, TGF-β shifted IL-10 regulation from a Blimp-1–dependent to a Blimp-1–independent pathway in IL-27–induced Tr1 (T regulatory 1) cells. Our findings further illustrate how IL-10 regulation in Th cells relies on several transcriptional programs that integrate various signals from the environment to fine-tune expression of this critical immunosuppressive cytokine. PMID:25073792

  11. Bottom depth and type for shallow waters: Hyperspectral observations from a blimp

    Energy Technology Data Exchange (ETDEWEB)

    Lee, ZhongPing; Carder, K.; Steward, R. [Univ. of South Florida, St. Petersburg, FL (United States)] [and others

    1997-08-01

    In a study of a blimp transect over Tampa Bay (Florida), hyperspectral upwelling radiance over the sand and seagrass bottoms was measured. These measurements were converted to hyperspectral remote-sensing reflectances. Using a shallow-water remote-sensing-reflectance model, in-water optical properties, bottom depths and bottom albedos were derived analytically and simultaneously by an optimization procedure. In the process, curvatures of sand and seagrass albedos were used. Also used was a model of absorption spectrum of phytoplankton pigments. The derived bottom depths were compared with bathymetry charts and found to agree well. This study suggests that a low-flying blimp is a useful platform for the study and mapping of coastal water environments. The optical model as well as the data-reduction procedure used are practical for the retrieval of shallow water optical properties.

  12. Noncoordinate expression of J-chain and Blimp-1 define nurse shark plasma cell populations during ontogeny.

    Science.gov (United States)

    Castro, Caitlin D; Ohta, Yuko; Dooley, Helen; Flajnik, Martin F

    2013-11-01

    B-lymphocyte-induced maturation protein 1 (Blimp-1) is the master regulator of plasma cell development, controlling genes such as those encoding J-chain and secretory Ig heavy chain. However, some mammalian plasma cells do not express J-chain, and mammalian B1 cells secrete "natural" IgM antibodies without upregulating Blimp-1. While these results have been controversial in mammalian systems, here we describe subsets of normally occurring Blimp-1(-) antibody-secreting cells in nurse sharks, found in lymphoid tissues at all ontogenic stages. Sharks naturally produce large amounts of both pentameric (classically "19S") and monomeric (classically "7S") IgM, the latter an indicator of adaptive immunity. Consistent with the mammalian paradigm, shark Blimp-1 is expressed in splenic 7S IgM-secreting cells, though rarely detected in the J-chain(+) cells producing 19S IgM. Although IgM transcript levels are lower in J-chain(+) cells, these cells nevertheless secrete 19S IgM in the absence of Blimp-1, as demonstrated by ELISPOT and metabolic labeling. Additionally, cells in the shark BM equivalent (epigonal) are Blimp-1(-). Our data suggest that, in sharks, 19S-secreting cells and other secreting memory B cells in the epigonal are maintained for long periods without Blimp-1, but like in mammals, Blimp-1 is required for terminating the B-cell program following an adaptive immune response in the spleen. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. New insights into Blimp-1 in T lymphocytes: a divergent regulator of cell destiny and effector function.

    Science.gov (United States)

    Fu, Shin-Huei; Yeh, Li-Tzu; Chu, Chin-Chen; Yen, B Lin-Ju; Sytwu, Huey-Kang

    2017-07-21

    B lymphocyte-induced maturation protein-1 (Blimp-1) serves as a master regulator of the development and function of antibody-producing B cells. Given that its function in T lymphocytes has been identified within the past decade, we review recent findings with emphasis on its role in coordinated control of gene expression during the development, differentiation, and function of T cells. Expression of Blimp-1 is mainly confined to activated T cells and is essential for the production of interleukin (IL)-10 by a subset of forkhead box (Fox)p3 + regulatory T cells with an effector phenotype. Blimp-1 is also required to induce cell elimination in the thymus and critically modulates peripheral T cell activation and proliferation. In addition, Blimp-1 promotes T helper (Th) 2 lineage commitment and limits Th1, Th17 and follicular helper T cell differentiation. Furthermore, Blimp-1 coordinates with other transcription factors to regulate expression of IL-2, IL-21 and IL-10 in effector T lymphocytes. In CD8 + T cells, Blimp-1 expression is distinct in heterogeneous populations at the stages of clonal expansion, differentiation, contraction and memory formation when they encounter antigens. Moreover, Blimp-1 plays a fundamental role in coordinating cytokine receptor signaling networks and transcriptional programs to regulate diverse aspects of the formation and function of effector and memory CD8 + T cells and their exhaustion. Blimp-1 also functions as a gatekeeper of T cell activation and suppression to prevent or dampen autoimmune disease, antiviral responses and antitumor immunity. In this review, we discuss the emerging roles of Blimp-1 in the complex regulation of gene networks that regulate the destiny and effector function of T cells and provide a Blimp-1-dominated transcriptional framework for T lymphocyte homeostasis.

  14. BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous Gland Progenitor under Steady-State Conditions

    Directory of Open Access Journals (Sweden)

    Kai Kretzschmar

    2014-10-01

    Full Text Available B-lymphocyte-induced nuclear maturation protein 1 (BLIMP1 was previously reported to define a sebaceous gland (SG progenitor population in the epidermis. However, the recent identification of multiple stem cell populations in the hair follicle junctional zone has led us to re-evaluate its function. We show, in agreement with previous studies, that BLIMP1 is expressed by postmitotic, terminally differentiated epidermal cells within the SG, interfollicular epidermis, and hair follicle. Epidermal overexpression of c-Myc results in loss of BLIMP1+ cells, an effect modulated by androgen signaling. Epidermal-specific deletion of Blimp1 causes multiple differentiation defects in the epidermis in addition to SG enlargement. In culture, BLIMP1+ sebocytes have no greater clonogenic potential than BLIMP1− sebocytes. Finally, lineage-tracing experiments reveal that, under steady-state conditions, BLIMP1-expressing cells do not divide. Thus, rather than defining a sebocyte progenitor population, BLIMP1 functions in terminally differentiated cells to maintain homeostasis in multiple epidermal compartments.

  15. Non-coordinate expression of J-chain and Blimp-1 define nurse shark plasma cell populations during ontogeny

    Science.gov (United States)

    Castro, Caitlin D.; Ohta, Yuko; Dooley, Helen; Flajnik, Martin F.

    2014-01-01

    Summary Blimp-1 is the master regulator of plasma cell development, controlling genes such as J-chain and secretory Ig heavy chain. However, some mammalian plasma cells do not express J-chain, and mammalian B1 cells secrete “natural” IgM antibodies without upregulating Blimp-1. While these results have been controversial in mammalian systems, here we describe subsets of normally occurring Blimp-1- antibody secreting cells in nurse sharks, found in lymphoid tissues at all ontogenic stages. Sharks naturally produce large amounts of both pentameric (classically ‘19S’) and monomeric (classically ‘7S’) IgM, the latter an indicator of adaptive immunity. Consistent with the mammalian paradigm, shark Blimp-1 is expressed in splenic 7S IgM-secreting cells, though rarely detected in the J-chain+ cells producing 19S IgM. Although IgM transcript levels are lower in J-chain+ cells, these cells nevertheless secrete 19S IgM in the absence of Blimp-1, as demonstrated by ELISPOT and metabolic labeling. Additionally, cells in the shark bone marrow equivalent (epigonal) are Blimp-1-. Our data suggest that, in sharks, 19S-secreting cells and other secreting memory B cells in the epigonal can be maintained for long periods without Blimp-1, but like in mammals, Blimp-1 is required for terminating the B cell program following an adaptive immune response in the spleen. PMID:23897025

  16. An historical experiment: Los Angeles smog evolution observed by blimp.

    Science.gov (United States)

    Hidy, G M

    2018-02-12

    Observations of smog over the Los Angeles Basin (LAB) links high oxidant mixing ratios with poor visibility, sometimes smog by blimp in a Lagrangian-like format. The experiment on September 6, 1973, demonstrated that a blimp could travel with the wind across the LAB, observing ozone (O 3 ) and precursors, and particles of different size ranges. These included condensation nuclei (CN) concentrations dominated by particles of ≤ 0.1 µm diameter and light scattering coefficient (b sc ) representing mainly particles of 0.1-2.0 µm diameter. The results indicated a pollutant variation similar to that measured at a fixed site. Ozone was produced in an air mass, reaching a maximum of ~400 ppb in the presence of nitrogen oxides (NO x ) and nonmethane hydrocarbons (NMHCs), then declined. Although the photochemistry was developing, b sc grew with O 3 mixing ratio to a quasi-steady state at ~9-10 × 10 -4  m -1 , decreasing in value much later with decease in O 3 . The light scattering coefficient was found to be positively associated with the O 3 mixing ratio, whereas CN concentrations were negatively proportional to O 3 mixing ratio. The blimp experiment was supported with aircraft vertical profiles and ground-level observations from a mobile laboratory. The blimp flight obtained combined gas and particle changes aloft that could not be obtained by ground or fixed-wing aircraft measurements alone. The experiment was partially successful in achieving a true Lagrangian characterization of smog chemistry in a constrained or defined "open" air mass. The Los Angeles experiment demonstrated the use of a blimp as a platform for measurement of air pollution traveling with an air mass across an urban area. The method added unique data showing the relationship between photochemical smog chemistry and aerosol dynamics in smog. The method offers an alternative to reliance on smog chamber and modeling observations to designing air quality management strategies for reactive

  17. Low Cost Lithography Tool for High Brightness LED Manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Andrew Hawryluk; Emily True

    2012-06-30

    The objective of this activity was to address the need for improved manufacturing tools for LEDs. Improvements include lower cost (both capital equipment cost reductions and cost-ofownership reductions), better automation and better yields. To meet the DOE objective of $1- 2/kilolumen, it will be necessary to develop these highly automated manufacturing tools. Lithography is used extensively in the fabrication of high-brightness LEDs, but the tools used to date are not scalable to high-volume manufacturing. This activity addressed the LED lithography process. During R&D and low volume manufacturing, most LED companies use contact-printers. However, several industries have shown that these printers are incompatible with high volume manufacturing and the LED industry needs to evolve to projection steppers. The need for projection lithography tools for LED manufacturing is identified in the Solid State Lighting Manufacturing Roadmap Draft, June 2009. The Roadmap states that Projection tools are needed by 2011. This work will modify a stepper, originally designed for semiconductor manufacturing, for use in LED manufacturing. This work addresses improvements to yield, material handling, automation and throughput for LED manufacturing while reducing the capital equipment cost.

  18. New concepts for interplanetary balloons and blimps, particularly for Titan

    Science.gov (United States)

    Nott, J.

    This paper proposes novel approaches for balloons for planets Titan BALLUTE A balloon or blimp arriving at a planet or moon with an atmosphere might inflate falling under a parachute or after landing Neither is ideal In both cases the envelope must include qualities needed for inflation as well as those for flight A ballute BALLoon parachUTE could be used thus a ballute is like a hot air balloon with a large mouth Initially it fills by ram pressure descending through an atmosphere As proposed it would then be heated by solid propellant It would stop descending and float level with hot air lift It is now a perfect location for inflation without wind or movement through the atmosphere and away from the uncertainties of the surface A ballute could be used over several bodies in the solar system BALLOONS FOR LOW TEMPERATURES Flight in very low temperatures is also discussed Conditions are so different that it is useful to examine basic factors These apply for any planet with low temperature and weather calm enough for balloons or blimps First for terrestrial hot air balloons thermal radiation is usually the dominant way heat is lost But radiation rises with the 4th power of absolute temperature At Titan radiation will be one or two orders of magnitude smaller Also the dense atmosphere allows small balloons small temperature differences So convection is small It appears a hot air balloon can easily be heated by a radioactive source likely carried to make electricity Pinholes are not important in such a balloon

  19. Blimp-1–mediated CD4 T cell exhaustion causes CD8 T cell dysfunction during chronic toxoplasmosis

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    Cobb, Dustin A.; Bhadra, Rajarshi

    2016-01-01

    CD8, but not CD4, T cells are considered critical for control of chronic toxoplasmosis. Although CD8 exhaustion has been previously reported in Toxoplasma encephalitis (TE)–susceptible model, our current work demonstrates that CD4 not only become exhausted during chronic toxoplasmosis but this dysfunction is more pronounced than CD8 T cells. Exhausted CD4 population expressed elevated levels of multiple inhibitory receptors concomitant with the reduced functionality and up-regulation of Blimp-1, a transcription factor. Our data demonstrates for the first time that Blimp-1 is a critical regulator for CD4 T cell exhaustion especially in the CD4 central memory cell subset. Using a tamoxifen-dependent conditional Blimp-1 knockout mixed bone marrow chimera as well as an adoptive transfer approach, we show that CD4 T cell–intrinsic deletion of Blimp-1 reversed CD8 T cell dysfunction and resulted in improved pathogen control. To the best of our knowledge, this is a novel finding, which demonstrates the role of Blimp-1 as a critical regulator of CD4 dysfunction and links it to the CD8 T cell dysfunctionality observed in infected mice. The critical role of CD4-intrinsic Blimp-1 expression in mediating CD4 and CD8 T cell exhaustion may provide a rational basis for designing novel therapeutic approaches. PMID:27481131

  20. Mouse Hobit is a homolog of the transcriptional repressor Blimp-1 that regulates NKT cell effector differentiation

    NARCIS (Netherlands)

    van Gisbergen, Klaas P. J. M.; Kragten, Natasja A. M.; Hertoghs, Kirsten M. L.; Wensveen, Felix M.; Jonjic, Stipan; Hamann, Jörg; Nolte, Martijn A.; van Lier, Rene A. W.

    2012-01-01

    The transcriptional repressor Blimp-1 mediates the terminal differentiation of many cell types, including T cells. Here we identified Hobit (Znf683) as a previously unrecognized homolog of Blimp-1 that was specifically expressed in mouse natural killer T cells (NKT cells). Through studies of

  1. Emergency transport by aeromedical blimp.

    Science.gov (United States)

    Cottrell, J J; Garrard, C

    1989-04-01

    Recently there has been an explosive growth in the use of helicopters and fixed wing aircraft for the transportation of patients who are ill and injured. Although using such methods of transport may result in faster access to health care centres, their ultimate role for the civilian population is unclear. Unfortunately, there are many problems associated with aeromedical transport, particularly with rotary wing aircraft, which have shown an alarming tendency to crash. The use of lighter than air vehicles (blimps, hot air balloons) might offer most of the advantages of conventional aieromedical transport, with an appreciable improvement in safety.

  2. Single cell analysis facilitates staging of Blimp1-dependent primordial germ cells derived from mouse embryonic stem cells.

    Directory of Open Access Journals (Sweden)

    John J Vincent

    Full Text Available The cell intrinsic programming that regulates mammalian primordial germ cell (PGC development in the pre-gonadal stage is challenging to investigate. To overcome this we created a transgene-free method for generating PGCs in vitro (iPGCs from mouse embryonic stem cells (ESCs. Using labeling for SSEA1 and cKit, two cell surface molecules used previously to isolate presumptive iPGCs, we show that not all SSEA1+/cKit+ double positive cells exhibit a PGC identity. Instead, we determined that selecting for cKit(bright cells within the SSEA1+ fraction significantly enriches for the putative iPGC population. Single cell analysis comparing SSEA1+/cKit(bright iPGCs to ESCs and embryonic PGCs demonstrates that 97% of single iPGCs co-express PGC signature genes Blimp1, Stella, Dnd1, Prdm14 and Dazl at similar levels to e9.5-10.5 PGCs, whereas 90% of single mouse ESC do not co-express PGC signature genes. For the 10% of ESCs that co-express PGC signature genes, the levels are significantly lower than iPGCs. Microarray analysis shows that iPGCs are transcriptionally distinct from ESCs and repress gene ontology groups associated with mesoderm and heart development. At the level of chromatin, iPGCs contain 5-methyl cytosine bases in their DNA at imprinted and non-imprinted loci, and are enriched in histone H3 lysine 27 trimethylation, yet do not have detectable levels of Mvh protein, consistent with a Blimp1-positive pre-gonadal PGC identity. In order to determine whether iPGC formation is dependent upon Blimp1, we generated Blimp1 null ESCs and found that loss of Blimp1 significantly depletes SSEA1/cKit(bright iPGCs. Taken together, the generation of Blimp1-positive iPGCs from ESCs constitutes a robust model for examining cell-intrinsic regulation of PGCs during the Blimp1-positive stage of development.

  3. Laser Cladding of CPM Tool Steels on Hardened H13 Hot-Work Steel for Low-Cost High-Performance Automotive Tooling

    Science.gov (United States)

    Chen, J.; Xue, L.

    2012-06-01

    This paper summarizes our research on laser cladding of high-vanadium CPM® tool steels (3V, 9V, and 15V) onto the surfaces of low-cost hardened H13 hot-work tool steel to substantially enhance resistance against abrasive wear. The results provide great potential for fabricating high-performance automotive tooling (including molds and dies) at affordable cost. The microstructure and hardness development of the laser-clad tool steels so obtained are presented as well.

  4. Hypomethylation and Over-Expression of the Beta Isoform of BLIMP1 is Induced by Epstein-Barr Virus Infection of B Cells; Potential Implications for the Pathogenesis of EBV-Associated Lymphomas

    Directory of Open Access Journals (Sweden)

    Katerina Vrzalikova

    2012-10-01

    Full Text Available B-lymphocyte-induced maturation protein 1 (BLIMP1 exists as two major isoforms, α and β, which arise from alternate promoters. Inactivation of the full length BLIMP1α isoform is thought to contribute to B cell lymphomagenesis by blocking post-germinal centre (GC B cell differentiation. In contrast, the shorter β isoform is functionally impaired and over-expressed in several haematological malignancies, including diffuse large B cell lymphomas (DLBCL. We have studied the influence on BLIMP1β expression of the Epstein-Barr virus (EBV, a human herpesvirus that is implicated in the pathogenesis of several GC-derived lymphomas, including a subset of DLBCL and Hodgkin’s lymphoma (HL. We show that BLIMP1β expression is increased following the EBV infection of normal human tonsillar GC B cells. We also show that this change in expression is accompanied by hypomethylation of the BLIMP1β-specific promoter. Furthermore, we confirmed previous reports that the BLIMP1β promoter is hypomethylated in DLBCL cell lines and show for the first time that BLIMP1β is hypomethylated in the Hodgkin/Reed-Sternberg (HRS cells of HL. Our results provide evidence in support of a role for BLIMP1β in the pathogenesis of EBV-associated B cell lymphomas.

  5. Two-Stage Winch for Kites and Tethered Balloons or Blimps

    Science.gov (United States)

    Miles, Ted; Bland, Geoff

    2011-01-01

    A winch system provides a method for launch and recovery capabilities for kites and tethered blimps or balloons. Low power consumption is a key objective, as well as low weight for portability. This is accomplished by decoupling the tether-line storage and wind ing/ unwinding functions, and providing tailored and efficient mechanisms for each. The components of this system include rotational power input devices such as electric motors or other apparatus, line winding/unwinding reel(s), line storage reel(s), and independent drive trains. Power is applied to the wind/unwind reels to transport the tether line. Power is also applied to a line storage reel, from either the wind/unwind power source, the wind/unwind reel itself, or separate power source. The speeds of the two reels are synchronized, but not dependent on each other. This is accomplished via clutch mechanisms, variable transmissions, or independent motor controls. The speed of the storage reel is modulated as the effective diameter of the reel changes with line accumulation.

  6. A molecular threshold for effector CD8(+) T cell differentiation controlled by transcription factors Blimp-1 and T-bet.

    Science.gov (United States)

    Xin, Annie; Masson, Frederick; Liao, Yang; Preston, Simon; Guan, Tianxia; Gloury, Renee; Olshansky, Moshe; Lin, Jian-Xin; Li, Peng; Speed, Terence P; Smyth, Gordon K; Ernst, Matthias; Leonard, Warren J; Pellegrini, Marc; Kaech, Susan M; Nutt, Stephen L; Shi, Wei; Belz, Gabrielle T; Kallies, Axel

    2016-04-01

    T cell responses are guided by cytokines that induce transcriptional regulators, which ultimately control differentiation of effector and memory T cells. However, it is unknown how the activities of these molecular regulators are coordinated and integrated during the differentiation process. Using genetic approaches and transcriptional profiling of antigen-specific CD8(+) T cells, we reveal a common program of effector differentiation that is regulated by IL-2 and IL-12 signaling and the combined activities of the transcriptional regulators Blimp-1 and T-bet. The loss of both T-bet and Blimp-1 leads to abrogated cytotoxic function and ectopic IL-17 production in CD8(+) T cells. Overall, our data reveal two major overlapping pathways of effector differentiation governed by the availability of Blimp-1 and T-bet and suggest a model for cytokine-induced transcriptional changes that combine, quantitatively and qualitatively, to promote robust effector CD8(+) T cell differentiation.

  7. Low cost tooling material and process for graphite and Kevlar composites

    Science.gov (United States)

    Childs, William I.

    1987-01-01

    An Extruded Sheet Tooling Compound (ESTC) was developed for use in quickly building low cost molds for fabricating composites. The ESTC is a very highly mineral-filled resin system formed into a 6 mm thick sheet. The sheet is laid on the pattern, vacuum (bag) is applied to remove air from the pattern surface, and the assembly is heat cured. The formed ESTC is then backed and/or framed and ready for use. The cured ESTC exhibits low coefficient of thermal expansion and maintains strength at temperatures of 180 to 200 C. Tools were made and used successfully for: Compression molding of high strength epoxy sheet molding compound, stamping of aluminum, resin transfer molding of polyester, and liquid resin molding of polyester. Several variations of ESTC can be made for specific requirements. Higher thermal conductivity can be achieved by using an aluminum particle filler. Room temperature gel is possible to allow use of foam patterns.

  8. OOTW COST TOOLS

    Energy Technology Data Exchange (ETDEWEB)

    HARTLEY, D.S.III; PACKARD, S.L.

    1998-09-01

    This document reports the results of a study of cost tools to support the analysis of Operations Other Than War (OOTW). It recommends the continued development of the Department of Defense (DoD) Contingency Operational Support Tool (COST) as the basic cost analysis tool for 00TWS. It also recommends modifications to be included in future versions of COST and the development of an 00TW mission planning tool to supply valid input for costing.

  9. Decreased Bcl-6 and increased Blimp-1 in the peritoneal cavity of patients with endometriosis.

    Science.gov (United States)

    Yeol, S G; Won, Y S; Kim, Y I; Lee, J W; Choi, Y J; Park, D C

    2015-01-01

    The authors investigated the expression patterns of interleukin (IL)-lβ and tumor necrosis factor (TNF)-α, cytokines associated with peritoneal inflammatory reactions, and of B cell leukemia lymphoma (Bcl)-6 and B lymphocyte inducer of maturation program (Blimp)-1, transcriptional factors associated with immunoglobulin (Ig) production; the concentrations of Igs, and their correlation, in patients with and without endometriosis. The authors analyzed the peritoneal fluid of 98 patients, 46 with endometriosis, and 52 with benign tumors. IL-1 and TNF-α mRNAs and IgG and IgA concentrations were higher in the endometriosis group, but the differences were not statistically significant. However, Bcl-6 mRNA level was significantly lower and Blimp-1 mRNA level was significantly higher in the endometriosis group with significant correlations among transcriptional factors, Igs, and cytokines (p Peritoneal immune responses in patients with endometriosis may be due to increased IgG and IgA concentrations, as well as to changes in expression of proinflammatory cytokines and transcriptional factors.

  10. low-cost apparatus from locally available materials for teaching

    African Journals Online (AJOL)

    unesco

    twofold: i) to design and produce appropriate low cost apparatus from locally .... How are the low-cost and manufactured apparatus compared in terms of cost and efficiency? ... BASIC TOOLS FOR THE LOW COST APPARATUS PRODUCTION.

  11. Improving Balance in TBI Using a Low-Cost Customized Virtual Reality Rehabilitation Tool

    Science.gov (United States)

    2016-10-01

    quality of life , and cognitive function. This design will allow us to assess the efficacy of IQ as a customizable balance treatment in TBI, and to...VANJHCS.  As  such,  we  have   explored  additional  avenues  and  are   working  closely  with  the  dedicated...AWARD NUMBER: W81XWH-14-2-0150 TITLE: Improving Balance in TBI Using a Low-Cost Customized Virtual Reality Rehabilitation Tool PRINCIPAL

  12. IL-33 inhibits RANKL-induced osteoclast formation through the regulation of Blimp-1 and IRF-8 expression

    Energy Technology Data Exchange (ETDEWEB)

    Kiyomiya, Hiroyasu [Division of Infections and Molecular Biology, Department of Health Promotion, Kyushu Dental University, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu, Fukuoka 803-8580 (Japan); Division of Oral and Maxillofacial Surgery, Department of Science of Physical Functions, Kyushu Dental University, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu, Fukuoka 803-8580 (Japan); Ariyoshi, Wataru; Okinaga, Toshinori [Division of Infections and Molecular Biology, Department of Health Promotion, Kyushu Dental University, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu, Fukuoka 803-8580 (Japan); Kaneuji, Takeshi [Division of Oral Medicine, Department of Science of Physical Functions, Kyushu Dental University, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu, Fukuoka 803-8580 (Japan); Mitsugi, Sho [Division of Oral and Maxillofacial Surgery, Department of Science of Physical Functions, Kyushu Dental University, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu, Fukuoka 803-8580 (Japan); Sakurai, Takuma [Division of Infections and Molecular Biology, Department of Health Promotion, Kyushu Dental University, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu, Fukuoka 803-8580 (Japan); Division of Oral and Maxillofacial Surgery, Department of Science of Physical Functions, Kyushu Dental University, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu, Fukuoka 803-8580 (Japan); Habu, Manabu [Division of Oral and Maxillofacial Surgery, Department of Science of Physical Functions, Kyushu Dental University, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu, Fukuoka 803-8580 (Japan); Yoshioka, Izumi [Division of Oral Medicine, Department of Science of Physical Functions, Kyushu Dental University, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu, Fukuoka 803-8580 (Japan); Tominaga, Kazuhiro [Division of Oral and Maxillofacial Surgery, Department of Science of Physical Functions, Kyushu Dental University, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu, Fukuoka 803-8580 (Japan); and others

    2015-05-01

    Interleukin (IL)-33 is a recently discovered proinflammatory cytokine that belongs to the IL-1 family. Several studies have reported that IL-33 inhibits osteoclast differentiation. However, the mechanism of IL-33 regulation of osteoclastogenesis remains unclear. In the present study, we examined the effect of IL-33 on osteoclast formation in vitro. IL-33 suppressed osteoclast formation in both mouse bone marrow cells and monocyte/macrophage cell line RAW264.7 cells induced by receptor activator of NF-κB ligand (RANKL) and/or macrophage stimulating factor (M-CSF). IL-33 also inhibited the expression of RANKL-induced nuclear factor of activated T-cell cytoplasmic 1 (NFATc1), thereby decreasing the expression of osteoclastogenesis-related marker genes, including Cathepsin K, Osteoclast stimulatory transmembrane protein (Oc-stamp) and Tartrate-resistant acid phosphatase (Trap). Blockage of IL-33-ST2 binding suppressed the IL-33-mediated inhibition of NFATc1. RANKL-induced B-lymphocyte-induced maturation protein-1 (Blimp-1) expression was also suppressed by IL-33, which was followed by the stimulation of anti-osteoclastic genes such as interferon regulatory factor-8 (IRF-8). These results suggest that IL-33-ST2 interactions down-regulate both RANKL-induced NFATc1 activation and osteoclast differentiation via the regulation of Blimp-1 and IRF-8 expression. - Highlights: • IL-33 inhibits RANKL-induced osteoclast formation. • IL-33 has inhibitory effect on the RANKL-induced NFATc1 expression. • IL-33-induced NFATc1 suppression depends on the regulation of Blimp-1 and IRF-8.

  13. IL-33 inhibits RANKL-induced osteoclast formation through the regulation of Blimp-1 and IRF-8 expression

    International Nuclear Information System (INIS)

    Kiyomiya, Hiroyasu; Ariyoshi, Wataru; Okinaga, Toshinori; Kaneuji, Takeshi; Mitsugi, Sho; Sakurai, Takuma; Habu, Manabu; Yoshioka, Izumi; Tominaga, Kazuhiro

    2015-01-01

    Interleukin (IL)-33 is a recently discovered proinflammatory cytokine that belongs to the IL-1 family. Several studies have reported that IL-33 inhibits osteoclast differentiation. However, the mechanism of IL-33 regulation of osteoclastogenesis remains unclear. In the present study, we examined the effect of IL-33 on osteoclast formation in vitro. IL-33 suppressed osteoclast formation in both mouse bone marrow cells and monocyte/macrophage cell line RAW264.7 cells induced by receptor activator of NF-κB ligand (RANKL) and/or macrophage stimulating factor (M-CSF). IL-33 also inhibited the expression of RANKL-induced nuclear factor of activated T-cell cytoplasmic 1 (NFATc1), thereby decreasing the expression of osteoclastogenesis-related marker genes, including Cathepsin K, Osteoclast stimulatory transmembrane protein (Oc-stamp) and Tartrate-resistant acid phosphatase (Trap). Blockage of IL-33-ST2 binding suppressed the IL-33-mediated inhibition of NFATc1. RANKL-induced B-lymphocyte-induced maturation protein-1 (Blimp-1) expression was also suppressed by IL-33, which was followed by the stimulation of anti-osteoclastic genes such as interferon regulatory factor-8 (IRF-8). These results suggest that IL-33-ST2 interactions down-regulate both RANKL-induced NFATc1 activation and osteoclast differentiation via the regulation of Blimp-1 and IRF-8 expression. - Highlights: • IL-33 inhibits RANKL-induced osteoclast formation. • IL-33 has inhibitory effect on the RANKL-induced NFATc1 expression. • IL-33-induced NFATc1 suppression depends on the regulation of Blimp-1 and IRF-8

  14. High Thermal Conductivity and High Wear Resistance Tool Steels for cost-effective Hot Stamping Tools

    Science.gov (United States)

    Valls, I.; Hamasaiid, A.; Padré, A.

    2017-09-01

    In hot stamping/press hardening, in addition to its shaping function, the tool controls the cycle time, the quality of the stamped components through determining the cooling rate of the stamped blank, the production costs and the feasibility frontier for stamping a given component. During the stamping, heat is extracted from the stamped blank and transported through the tool to the cooling medium in the cooling lines. Hence, the tools’ thermal properties determine the cooling rate of the blank, the heat transport mechanism, stamping times and temperature distribution. The tool’s surface resistance to adhesive and abrasive wear is also an important cost factor, as it determines the tool durability and maintenance costs. Wear is influenced by many tool material parameters, such as the microstructure, composition, hardness level and distribution of strengthening phases, as well as the tool’s working temperature. A decade ago, Rovalma developed a hot work tool steel for hot stamping that features a thermal conductivity of more than double that of any conventional hot work tool steel. Since that time, many complimentary grades have been developed in order to provide tailored material solutions as a function of the production volume, degree of blank cooling and wear resistance requirements, tool geometries, tool manufacturing method, type and thickness of the blank material, etc. Recently, Rovalma has developed a new generation of high thermal conductivity, high wear resistance tool steel grades that enable the manufacture of cost effective tools for hot stamping to increase process productivity and reduce tool manufacturing costs and lead times. Both of these novel grades feature high wear resistance and high thermal conductivity to enhance tool durability and cut cycle times in the production process of hot stamped components. Furthermore, one of these new grades reduces tool manufacturing costs through low tool material cost and hardening through readily

  15. A biological timer in the fat body comprising Blimp-1, βFtz-f1 and Shade regulates pupation timing in Drosophila melanogaster.

    Science.gov (United States)

    Akagi, Kazutaka; Sarhan, Moustafa; Sultan, Abdel-Rahman S; Nishida, Haruka; Koie, Azusa; Nakayama, Takumi; Ueda, Hitoshi

    2016-07-01

    During the development of multicellular organisms, many events occur with precise timing. In Drosophila melanogaster, pupation occurs about 12 h after puparium formation and its timing is believed to be determined by the release of a steroid hormone, ecdysone (E), from the prothoracic gland. Here, we demonstrate that the ecdysone-20-monooxygenase Shade determines pupation timing by converting E to 20-hydroxyecdysone (20E) in the fat body, which is the organ that senses nutritional status. The timing of shade expression is determined by its transcriptional activator βFtz-f1. The βftz-f1 gene is activated after a decline in the expression of its transcriptional repressor Blimp-1, which is temporally expressed around puparium formation in response to a high titer of 20E. The expression level and stability of Blimp-1 is critical for the precise timing of pupation. Thus, we propose that Blimp-1 molecules function like sand in an hourglass in this precise developmental timer system. Furthermore, our data suggest that a biological advantage results from both the use of a transcriptional repressor for time determination and the association of developmental timing with nutritional status of the organism. © 2016. Published by The Company of Biologists Ltd.

  16. Gold nanoparticles regulate the blimp1/pax5 pathway and enhance antibody secretion in B-cells

    International Nuclear Information System (INIS)

    Lee, Chia-Hui; Syu, Shih-Han; Steven Huang, G; Chen, Yu-Shiun; Chen, Wen Liang; Hussain, Saber M; Aleksandrovich Onischuk, Andrei

    2014-01-01

    Nanoparticles are potential threats to human health and the environment; however, their medical applications as drug carriers targeting cancer cells bring hope to contemporary cancer therapy. As a model drug carrier, gold nanoparticles (GNPs) have been investigated extensively for in vivo toxicity. The effect of GNPs on the immune system, however, has rarely been examined. Antibody-secreting cells were treated with GNPs with diameters ranging from 2 to 50 nm. The GNPs enhanced IgG secretion in a size-dependent manner, with a peak of efficacy at 10 nm. The immune-stimulatory effect reached a maximum at 12 h after treatment but returned to control levels 24 h after treatment. This enhancing effect was validated ex vivo using B-cells isolated from mouse spleen. Evidence from RT-PCR and western blot experiments indicates that GNP-treatment upregulated B-lymphocyte-induced maturation protein 1 (blimp1) and downregulated paired box 5 (pax5). Immunostaining for blimp1 and pax5 in B-cells confirmed that the GNPs stimulated IgG secretion through the blimp1/pax5 pathway. The immunization of mice using peptide-conjugated GNPs indicated that the GNPs were capable of enhancing humoral immunity in a size-dependent manner. This effect was consistent with the bio-distribution of the GNPs in mouse spleen. In conclusion, in vitro, ex vivo, and in vivo evidence supports our hypothesis that GNPs enhance humoral immunity in mouse. The effect on the immune system should be taken into account if nanoparticles are used as carriers for drug delivery. In addition to their toxicity, the immune-stimulatory activity of nanoparticles could play an important role in human health and could have an environmental impact. (paper)

  17. Low cost, low tech SNP genotyping tools for resource-limited areas: Plague in Madagascar as a model.

    Directory of Open Access Journals (Sweden)

    Cedar L Mitchell

    2017-12-01

    Full Text Available Genetic analysis of pathogenic organisms is a useful tool for linking human cases together and/or to potential environmental sources. The resulting data can also provide information on evolutionary patterns within a targeted species and phenotypic traits. However, the instruments often used to generate genotyping data, such as single nucleotide polymorphisms (SNPs, can be expensive and sometimes require advanced technologies to implement. This places many genotyping tools out of reach for laboratories that do not specialize in genetic studies and/or lack the requisite financial and technological resources. To address this issue, we developed a low cost and low tech genotyping system, termed agarose-MAMA, which combines traditional PCR and agarose gel electrophoresis to target phylogenetically informative SNPs.To demonstrate the utility of this approach for generating genotype data in a resource-constrained area (Madagascar, we designed an agarose-MAMA system targeting previously characterized SNPs within Yersinia pestis, the causative agent of plague. We then used this system to genetically type pathogenic strains of Y. pestis in a Malagasy laboratory not specialized in genetic studies, the Institut Pasteur de Madagascar (IPM. We conducted rigorous assay performance validations to assess potential variation introduced by differing research facilities, reagents, and personnel and found no difference in SNP genotyping results. These agarose-MAMA PCR assays are currently employed as an investigative tool at IPM, providing Malagasy researchers a means to improve the value of their plague epidemiological investigations by linking outbreaks to potential sources through genetic characterization of isolates and to improve understanding of disease ecology that may contribute to a long-term control effort.The success of our study demonstrates that the SNP-based genotyping capacity of laboratories in developing countries can be expanded with manageable

  18. Low cost, low tech SNP genotyping tools for resource-limited areas: Plague in Madagascar as a model.

    Science.gov (United States)

    Mitchell, Cedar L; Andrianaivoarimanana, Voahangy; Colman, Rebecca E; Busch, Joseph; Hornstra-O'Neill, Heidie; Keim, Paul S; Wagner, David M; Rajerison, Minoarisoa; Birdsell, Dawn N

    2017-12-01

    Genetic analysis of pathogenic organisms is a useful tool for linking human cases together and/or to potential environmental sources. The resulting data can also provide information on evolutionary patterns within a targeted species and phenotypic traits. However, the instruments often used to generate genotyping data, such as single nucleotide polymorphisms (SNPs), can be expensive and sometimes require advanced technologies to implement. This places many genotyping tools out of reach for laboratories that do not specialize in genetic studies and/or lack the requisite financial and technological resources. To address this issue, we developed a low cost and low tech genotyping system, termed agarose-MAMA, which combines traditional PCR and agarose gel electrophoresis to target phylogenetically informative SNPs. To demonstrate the utility of this approach for generating genotype data in a resource-constrained area (Madagascar), we designed an agarose-MAMA system targeting previously characterized SNPs within Yersinia pestis, the causative agent of plague. We then used this system to genetically type pathogenic strains of Y. pestis in a Malagasy laboratory not specialized in genetic studies, the Institut Pasteur de Madagascar (IPM). We conducted rigorous assay performance validations to assess potential variation introduced by differing research facilities, reagents, and personnel and found no difference in SNP genotyping results. These agarose-MAMA PCR assays are currently employed as an investigative tool at IPM, providing Malagasy researchers a means to improve the value of their plague epidemiological investigations by linking outbreaks to potential sources through genetic characterization of isolates and to improve understanding of disease ecology that may contribute to a long-term control effort. The success of our study demonstrates that the SNP-based genotyping capacity of laboratories in developing countries can be expanded with manageable financial cost for

  19. Control Strategy Tool (CoST)

    Data.gov (United States)

    U.S. Environmental Protection Agency — The EPA Control Strategy Tool (CoST) is a software tool for projecting potential future control scenarios, their effects on emissions and estimated costs. This tool...

  20. Low-cost Tools for Aerial Video Geolocation and Air Traffic Analysis for Delay Reduction Using Google Earth

    Science.gov (United States)

    Zetterlind, V.; Pledgie, S.

    2009-12-01

    Low-cost, low-latency, robust geolocation and display of aerial video is a common need for a wide range of earth observing as well as emergency response and security applications. While hardware costs for aerial video collection systems, GPS, and inertial sensors have been decreasing, software costs for geolocation algorithms and reference imagery/DTED remain expensive and highly proprietary. As part of a Federal Small Business Innovative Research project, MosaicATM and EarthNC, Inc have developed a simple geolocation system based on the Google Earth API and Google's 'built-in' DTED and reference imagery libraries. This system geolocates aerial video based on platform and camera position, attitude, and field-of-view metadata using geometric photogrammetric principles of ray-intersection with DTED. Geolocated video can be directly rectified and viewed in the Google Earth API during processing. Work is underway to extend our geolocation code to NASA World Wind for additional flexibility and a fully open-source platform. In addition to our airborne remote sensing work, MosaicATM has developed the Surface Operations Data Analysis and Adaptation (SODAA) tool, funded by NASA Ames, which supports analysis of airport surface operations to optimize aircraft movements and reduce fuel burn and delays. As part of SODAA, MosaicATM and EarthNC, Inc have developed powerful tools to display national airspace data and time-animated 3D flight tracks in Google Earth for 4D analysis. The SODAA tool can convert raw format flight track data, FAA National Flight Data (NFD), and FAA 'Adaptation' airport surface data to a spatial database representation and then to Google Earth KML. The SODAA client provides users with a simple graphical interface through which to generate queries with a wide range of predefined and custom filters, plot results, and export for playback in Google Earth in conjunction with NFD and Adaptation overlays.

  1. Loss of PRDM1/BLIMP-1 function contributes to poor prognosis of activated B-cell-like diffuse large B-cell lymphoma

    DEFF Research Database (Denmark)

    Xia, Yi; Xu-Monette, Z Y; Tzankov, A

    2017-01-01

    PRDM1/BLIMP-1, a master regulator of plasma-cell differentiation, is frequently inactivated in activated B-cell-like (ABC) diffuse large B-cell lymphoma (DLBCL) patients. Little is known about its genetic aberrations and relevant clinical implications. A large series of patients with de novo DLBC...

  2. Low-cost computer mouse for the elderly or disabled in Taiwan.

    Science.gov (United States)

    Chen, C-C; Chen, W-L; Chen, B-N; Shih, Y-Y; Lai, J-S; Chen, Y-L

    2014-01-01

    A mouse is an important communication interface between a human and a computer, but it is still difficult to use for the elderly or disabled. To develop a low-cost computer mouse auxiliary tool. The principal structure of the low-cost mouse auxiliary tool is the IR (infrared ray) array module and the Wii icon sensor module, which combine with reflective tape and the SQL Server database. This has several benefits including cheap hardware cost, fluent control, prompt response, adaptive adjustment and portability. Also, it carries the game module with the function of training and evaluation; to the trainee, it is really helpful to upgrade the sensitivity of consciousness/sense and the centralization of attention. The intervention phase/maintenance phase, with regard to clicking accuracy and use of time, p value (p< 0.05) reach the level of significance. The development of the low cost adaptive computer mouse auxiliary tool was completed during the study and was also verified as having the characteristics of low cost, easy operation and the adaptability. To patients with physical disabilities, if they have independent control action parts of their limbs, the mouse auxiliary tool is suitable for them to use, i.e. the user only needs to paste the reflective tape by the independent control action parts of the body to operate the mouse auxiliary tool.

  3. Spreadsheet tool for estimating noise reduction costs

    International Nuclear Information System (INIS)

    Frank, L.; Senden, V.; Leszczynski, Y.

    2009-01-01

    The Northeast Capital Industrial Association (NCIA) represents industry in Alberta's industrial heartland. The organization is in the process of developing a regional noise management plan (RNMP) for their member companies. The RNMP includes the development of a noise reduction cost spreadsheet tool to conduct reviews of practical noise control treatments available for individual plant equipment, inclusive of ranges of noise attenuation achievable, which produces a budgetary prediction of the installed cost of practical noise control treatments. This paper discussed the noise reduction cost spreadsheet tool, with particular reference to noise control best practices approaches and spreadsheet tool development such as prerequisite, assembling data required, approach, and unit pricing database. Use and optimization of the noise reduction cost spreadsheet tool was also discussed. It was concluded that the noise reduction cost spreadsheet tool is an easy interactive tool to estimate implementation costs related to different strategies and options of noise control mitigating measures and was very helpful in gaining insight for noise control planning purposes. 2 tabs.

  4. Low-Cost Air Quality Monitoring Tools: From Research to Practice (A Workshop Summary

    Directory of Open Access Journals (Sweden)

    Andrea L. Clements

    2017-10-01

    Full Text Available In May 2017, a two-day workshop was held in Los Angeles (California, U.S.A. to gather practitioners who work with low-cost sensors used to make air quality measurements. The community of practice included individuals from academia, industry, non-profit groups, community-based organizations, and regulatory agencies. The group gathered to share knowledge developed from a variety of pilot projects in hopes of advancing the collective knowledge about how best to use low-cost air quality sensors. Panel discussion topics included: (1 best practices for deployment and calibration of low-cost sensor systems, (2 data standardization efforts and database design, (3 advances in sensor calibration, data management, and data analysis and visualization, and (4 lessons learned from research/community partnerships to encourage purposeful use of sensors and create change/action. Panel discussions summarized knowledge advances and project successes while also highlighting the questions, unresolved issues, and technological limitations that still remain within the low-cost air quality sensor arena.

  5. Hot forming and quenching pilot process development for low cost and low environmental impact manufacturing.

    Science.gov (United States)

    Hall, Roger W.; Foster, Alistair; Herrmann Praturlon, Anja

    2017-09-01

    The Hot Forming and in-tool Quenching (HFQ®) process is a proven technique to enable complex shaped stampings to be manufactured from high strength aluminium. Its widespread uptake for high volume production will be maximised if it is able to wholly amortise the additional investment cost of this process compared to conventional deep drawing techniques. This paper discusses the use of three techniques to guide some of the development decisions taken during upscaling of the HFQ® process. Modelling of Process timing, Cost and Life-cycle impact were found to be effective tools to identify where development budget could be focused in order to be able to manufacture low cost panels of different sizes from many different alloys in a sustainable way. The results confirm that raw material cost, panel trimming, and artificial ageing were some of the highest contributing factors to final component cost. Additionally, heat treatment and lubricant removal stages played a significant role in the overall life-cycle assessment of the final products. These findings confirmed development priorities as novel furnace design, fast artificial ageing and low-cost alloy development.

  6. The Locus of Tool-Transformation Costs

    Science.gov (United States)

    Kunde, Wilfried; Pfister, Roland; Janczyk, Markus

    2012-01-01

    Transformations of hand movements by tools such as levers or electronic input devices can invoke performance costs compared to untransformed movements. This study investigated by means of the Psychological Refractory Period (PRP) paradigm at which stage of information processing such tool-transformation costs arise. We used an inversion…

  7. The Stabilization of Position and Attitude for a Blimp by a Switching Controller

    Directory of Open Access Journals (Sweden)

    Yoshikazu Nakamura

    2017-03-01

    Full Text Available In recent years, the development of unmanned air vehicles aiming at vegetation observation, information gathering of a disaster site, etc. is increasing. Among them, airships are attractive because of good energy efficiency and it is possible to be employed for a long time cruise. Especially, small airships called “blimp” have been developing to make the management easy. Although most of existing airships employ control methods by combining propellers and rudders, such a control approach has the problem that the maneuverability is deteriorated if their traveling speed is slow because the airflow received by rudders is weakened. In this research, “X4-Blimp” is proposed as a blimp controlled by only four propellers without any rudders, and it is controlled by a switching controller.

  8. iTunes song-gifting is a low-cost, efficient recruitment tool to engage high-risk MSM in internet research.

    Science.gov (United States)

    Holland, Christine M; Ritchie, Natalie D; Du Bois, Steve N

    2015-10-01

    This brief report describes methodology and results of a novel, efficient, and low-cost recruitment tool to engage high-risk MSM in online research. We developed an incentivization protocol using iTunes song-gifting to encourage participation of high-risk MSM in an Internet-based survey of HIV status, childhood sexual abuse, and adult behavior and functioning. Our recruitment methodology yielded 489 participants in 4.5 months at a total incentive cost of $1.43USD per participant. The sample comprised a critically high-risk group of MSM, including 71.0 % who reported recent condomless anal intercourse. We offer a "how-to" guide to aid future investigators in using iTunes song-gifting incentives.

  9. Low cost drip irrigation in Burkina Faso : unravelling actors, networks and practices

    NARCIS (Netherlands)

    Wanvoeke, M.J.V.

    2015-01-01

    Title: Low cost drip irrigation in Burkina Faso: Unravelling Actors, Networks and Practices

    In Burkina Faso, there is a lot of enthusiasm about Low Cost Drip Irrigation (LCDI) as a tool to irrigate vegetables, and thus improve food security,

  10. Pathways of low carbon transition at the lowest cost. Pathways of low carbon transition in France at the lowest cost - Dynamics and average abatement costs (MACC)

    International Nuclear Information System (INIS)

    Perrissin Fabert, Baptiste; Foussard, Alexis

    2016-11-01

    The objective to divide greenhouse gas emissions in France by a factor four by 2050 implies the mobilisation at the lowest cost of the whole set of known sources of reduction of emissions in all economic sectors. In this context, this report is based on a methodology (D-CAM in French for dynamics - average abatement costs, MACC in English for Medium Abatement Cost Curves) which relies on a theoretical business-as-usual scenario, on a database on the potential, rate of development, and cost of mobilizable sources, and on a dynamic model of cost minimisation. The MACC tool is used to explore, for each sector, scenarios of de-carbonation which allow objectives of reduction of greenhouse gas emissions to be reached at different time horizons. An aggregated approach of this tool modifies the distribution of efforts of emission reduction between sectors with respect to a sector-based approach. Thus, a macro-assessment of low carbon transition does not reveal any obvious over-cost with respect to the business-as-usual scenario. A second document is a Power Point presentation which contains the same information, curves and graphs

  11. Development and analysis of a low-cost screening tool to identify and classify hearing loss in children: a proposal for developing countries

    Directory of Open Access Journals (Sweden)

    Alessandra Giannella Samelli

    2011-01-01

    Full Text Available OBJECTIVE: A lack of attention has been given to hearing health in primary care in developing countries. A strategy involving low-cost screening tools may fill the current gap in hearing health care provided to children. Therefore, it is necessary to establish and adopt lower-cost procedures that are accessible to underserved areas that lack other physical or human resources that would enable the identification of groups at risk for hearing loss. The aim of this study was to develop and analyze the efficacy of a low-cost screening tool to identify and classify hearing loss in children. METHODS: A total of 214 2-to-10 year-old children participated in this study. The study was conducted by providing a questionnaire to the parents and comparing the answers with the results of a complete audiological assessment. Receiver operating characteristic (ROC curves were constructed, and discriminant analysis techniques were used to classify each child based on the total score. RESULTS: We found conductive hearing loss in 39.3% of children, sensorineural hearing loss in 7.4% and normal hearing in 53.3%. The discriminant analysis technique provided the following classification rule for the total score on the questionnaire: 0 to 4 points - normal hearing; 5 to 7 points - conductive hearing loss; over 7 points - sensorineural hearing loss. CONCLUSION: Our results suggest that the questionnaire could be used as a screening tool to classify children with normal hearing or hearing loss and according to the type of hearing loss based on the total questionnaire score

  12. Development of low-friction and wear-resistant surfaces for low-cost Al hot stamping tools

    Directory of Open Access Journals (Sweden)

    Dong Y.

    2015-01-01

    Full Text Available In this study, advanced surfaces and coatings have been developed using plasma thermochemical treatment, PVD coating, electroless Ni-BN plating and duplex surface engineering to produce low-friction and wear-resistant surfaces for cast iron stamping tools. Their microstructural and nano-mechanical properties were systematically analysed and the tribological behaviour of these new surfaces and coatings were evaluated. The experimental results have shown that under dry sliding condition, the tribological behaviour of aluminium differed great from that of steel regardless of the counterpart material. Highly reactive aluminium had a strong tendency to solder with tool surfaces during dry sliding. However, the lubricity of gray cast irons can be significantly improved by Ni-BN and DLC coatings. The coefficient of friction reduced from about 0.5 for untreated cast irons to about 0.2 sliding against aluminium. Duplex treatment combining plasma nitrocarburising with low-friction coatings showed superior durability than both DLC and Ni-BN coatings.

  13. Low-cost, low-weight CNG cylinder development. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Richards, Mark E.; Melford, K.; Wong, J.; Gambone, L.

    1999-09-01

    This program was established to develop and commercialize new high-strength steel-lined, composite hoop-wrapped compressed natural gas (CNG) cylinders for vehicular applications. As much as 70% of the cost of natural gas vehicles can be related to on-board natural gas storage costs. The cost and weight targets for this program represent significant savings in each characteristic when compared to comparable containers available at the initiation of the program. The program objectives were to optimize specific weight and cost goals, yielding CNG cylinders with dimensions that should, allowing for minor modifications, satisfy several vehicle market segments. The optimization process encompassed material, design, and process improvement. In optimizing the CNG cylinder design, due consideration was given to safety aspects relative to national, international, and vehicle manufacturer cylinder standards and requirements. The report details the design and development effort, encompassing plant modifications, material selection, design issues, tooling development, prototype development, and prototype testing. Extenuating circumstances prevented the immediate commercialization of the cylinder designs, though significant progress was made towards improving the cost and performance of CNG cylinders. A new low-cost fiber was successfully employed while the weight target was met and the cost target was missed by less than seven percent.

  14. Towards open-source, low-cost haptics for surgery simulation.

    Science.gov (United States)

    Suwelack, Stefan; Sander, Christian; Schill, Julian; Serf, Manuel; Danz, Marcel; Asfour, Tamim; Burger, Wolfgang; Dillmann, Rüdiger; Speidel, Stefanie

    2014-01-01

    In minimally invasive surgery (MIS), virtual reality (VR) training systems have become a promising education tool. However, the adoption of these systems in research and clinical settings is still limited by the high costs of dedicated haptics hardware for MIS. In this paper, we present ongoing research towards an open-source, low-cost haptic interface for MIS simulation. We demonstrate the basic mechanical design of the device, the sensor setup as well as its software integration.

  15. Treatment Cost Analysis Tool (TCAT) for estimating costs of outpatient treatment services.

    Science.gov (United States)

    Flynn, Patrick M; Broome, Kirk M; Beaston-Blaakman, Aaron; Knight, Danica K; Horgan, Constance M; Shepard, Donald S

    2009-02-01

    A Microsoft Excel-based workbook designed for research analysts to use in a national study was retooled for treatment program directors and financial officers to allocate, analyze, and estimate outpatient treatment costs in the U.S. This instrument can also be used as a planning and management tool to optimize resources and forecast the impact of future changes in staffing, client flow, program design, and other resources. The Treatment Cost Analysis Tool (TCAT) automatically provides feedback and generates summaries and charts using comparative data from a national sample of non-methadone outpatient providers. TCAT is being used by program staff to capture and allocate both economic and accounting costs, and outpatient service costs are reported for a sample of 70 programs. Costs for an episode of treatment in regular, intensive, and mixed types of outpatient treatment were $882, $1310, and $1381 respectively (based on 20% trimmed means and 2006 dollars). An hour of counseling cost $64 in regular, $85 intensive, and $86 mixed. Group counseling hourly costs per client were $8, $11, and $10 respectively for regular, intensive, and mixed. Future directions include use of a web-based interview version, much like some of the commercially available tax preparation software tools, and extensions for use in other modalities of treatment.

  16. Towards low cost, efficient and stable organic photovoltaic modules

    Energy Technology Data Exchange (ETDEWEB)

    Andriessen, R. [Holst Centre - Solliance, PO Box 8550, 5605 KN Eindhoven (Netherlands); Kroon, J.M. [ECN - Solliance, Petten (Netherlands); Aernouts, T. [Imec, Solliance, Kapeldreef 75, B-3001 Leuven (Belgium); Janssen, R. [Eindhoven University of Technology, Solliance, Eindhoven (Netherlands)

    2012-09-15

    This article describes how the Solliance Organic PhotoVoltaics (OPV) shared research Program addresses efficiency, lifetime and production costs for (near) future OPV applications. The balance of these three parameters depends of the envisaged application, but at the end, OPV should be able to compete somehow with Si PV in the future. Efficiency improvements are realized by developing new materials, by exploring and optimizing new device structures and novel interconnection technologies. Lifetime improvements are realized by using stabilized device stacks and materials and by applying high end flexible barriers. Production cost control is done by using a home made Cost of Ownership tool which guides towards the use of low-cost materials and processes.

  17. Software for optimizing the cost of forming tools; Kosten fuer Umformwerkzeuge softwaretechnisch durchgehend im Griff

    Energy Technology Data Exchange (ETDEWEB)

    Fries, Daniel [Autoform Engineering GmbH, Zuerich (Switzerland)

    2009-08-31

    In spite of some major technical challenges, market prices of tools are that low that it may be cheaper to buy a ready-made tool on the world market than to buy the raw material for it. An example of the Daimler AG shows, however, that tool cost calculation may still be economically interesting in the car manufacturing and component manufacturing industry. (orig.)

  18. The ABCs of Activity-Based Costing: A Cost Containment and Reallocation Tool.

    Science.gov (United States)

    Turk, Frederick J.

    1992-01-01

    This article describes activity-based costing (ABC) and how this tool may help management understand the costs of major activities and identify possible alternatives. Also discussed are the traditional costing systems used by higher education and ways of applying ABC to higher education. (GLR)

  19. Rugged, Low Cost, Environmental Sensors for a Turbulent World

    Science.gov (United States)

    Schulz, B.; Sandell, C. T.; Wickert, A. D.

    2017-12-01

    Ongoing scientific research and resource management require a diverse range of high-quality and low-cost sensors to maximize the number and type of measurements that can be obtained. To accomplish this, we have developed a series of diversified sensors for common environmental applications. The TP-DownHole is an ultra-compact temperature and pressure sensor designed for use in CMT (Continuous Multi-channel Tubing) multi-level wells. Its 1 mm water depth resolution, 30 cm altitude resolution, and rugged design make it ideal for both water level measurements and monitoring barometric pressure and associated temperature changes. The TP-DownHole sensor has also been incorporated into a self-contained, fully independent data recorder for extreme and remote environments. This device (the TP-Solo) is based around the TP-DownHole design, but has self-contained power and data storage and is designed to collect data independently for up to 6 months (logging at once an hour), creating a specialized tool for extreme environment data collection. To gather spectral information, we have also developed a very low cost photodiode-based Lux sensor to measure spectral irradiance; while this does not measure the entire solar radiation spectrum, simple modeling to rescale the remainder of the solar spectrum makes this a cost-effective alternative to a thermopile pyranometer. Lastly, we have developed an instrumentation amplifier which is designed to interface a wide range of sensitive instruments to common data logging systems, such as thermopile pyranometers, thermocouples, and many other analog output sensors. These three instruments are the first in a diverse family aimed to give researchers a set of powerful and low-cost tools for environmental instrumentation.

  20. A software toolkit for implementing low-cost virtual reality training systems

    International Nuclear Information System (INIS)

    Louka, Michael N.

    1999-04-01

    VR is a powerful technology for implementing training systems but better tools are needed to achieve wider usage and acceptance for desktop computer-based training applications. A need has been identified for a software tool kit to support the efficient implementation of well-structured desktop VR training systems. A powerful toolkit for implementing scalable low-cost VR training applications is described in this report (author) (ml)

  1. Low-cost inertial measurement unit.

    Energy Technology Data Exchange (ETDEWEB)

    Deyle, Travis Jay

    2005-03-01

    Sandia National Laboratories performs many expensive tests using inertial measurement units (IMUs)--systems that use accelerometers, gyroscopes, and other sensors to measure flight dynamics in three dimensions. For the purpose of this report, the metrics used to evaluate an IMU are cost, size, performance, resolution, upgradeability and testing. The cost of a precision IMU is very high and can cost hundreds of thousands of dollars. Thus the goals and results of this project are as follows: (1) Examine the data flow in an IMU and determine a generic IMU design. (2) Discuss a high cost IMU implementation and its theoretically achievable results. (3) Discuss design modifications that would save money for suited applications. (4) Design and implement a low cost IMU and discuss its theoretically achievable results. (5) Test the low cost IMU and compare theoretical results with empirical results. (6) Construct a more streamlined printed circuit board design reducing noise, increasing capabilities, and constructing a self-contained unit. Using these results, we can compare a high cost IMU versus a low cost IMU using the metrics from above. Further, we can examine and suggest situations where a low cost IMU could be used instead of a high cost IMU for saving cost, size, or both.

  2. An Overview Of Tool For Response Action Cost Estimating (TRACE)

    International Nuclear Information System (INIS)

    Ferries, S.R.; Klink, K.L.; Ostapkowicz, B.

    2012-01-01

    Tools and techniques that provide improved performance and reduced costs are important to government programs, particularly in current times. An opportunity for improvement was identified for preparation of cost estimates used to support the evaluation of response action alternatives. As a result, CH2M HILL Plateau Remediation Company has developed Tool for Response Action Cost Estimating (TRACE). TRACE is a multi-page Microsoft Excel(reg s ign) workbook developed to introduce efficiencies into the timely and consistent production of cost estimates for response action alternatives. This tool combines costs derived from extensive site-specific runs of commercially available remediation cost models with site-specific and estimator-researched and derived costs, providing the best estimating sources available. TRACE also provides for common quantity and key parameter links across multiple alternatives, maximizing ease of updating estimates and performing sensitivity analyses, and ensuring consistency.

  3. Sensing of the atmospheric variation using Low Cost GNSS Receiver

    Science.gov (United States)

    Bramanto, Brian; Gumilar, Irwan; Sidiq, Teguh P.; Kuntjoro, Wedyanto; Tampubolon, Daniel A.

    2018-05-01

    As the GNSS signals transmitted through the atmosphere, they are delayed by interference of TEC (Total Electron Content) in the ionosphere and water vapor in the troposphere. By using inverse-problem, name GNSS Meteorology, those parameters can be obtained precisely and several researches has approved and supported that method. However, the geodetic GNSS receivers are relatively high cost (30,000 to 70,000 each) to be established on a regular and uniform network. This research aims to investigate the potential use of low cost GNSS receiver (less than 2,000) to observe the atmospheric dynamic both in ionosphere and troposphere. Results indicated that low cost GNSS receiver is a promising tools to sensing the atmospheric dynamic, however, further processing is needed to enhance the data quality. It is found that both of ionosphere and troposphere dynamic has diurnal periodic component.

  4. Low-Cost National Media-Based Surveillance System for Public Health Events, Bangladesh

    Science.gov (United States)

    Ao, Trong T.; Rahman, Mahmudur; Haque, Farhana; Chakraborty, Apurba; Hossain, M. Jahangir; Haider, Sabbir; Alamgir, A.S.M.; Sobel, Jeremy; Luby, Stephen P.

    2016-01-01

    We assessed a media-based public health surveillance system in Bangladesh during 2010–2011. The system is a highly effective, low-cost, locally appropriate, and sustainable outbreak detection tool that could be used in other low-income, resource-poor settings to meet the capacity for surveillance outlined in the International Health Regulations 2005. PMID:26981877

  5. Low-cost risk reduction strategy for small workplaces: how can we spread good practices?

    Science.gov (United States)

    Kogi, K

    2006-01-01

    Recent advances in health risk reduction approaches are examined based on inter-country networking experiences. A noteworthy progress is the wider application of low-cost improvements to risk reduction particularly in small enterprises and agriculture in both industrially developing and developed countries. This is helped by the readiness of managers and workers to implement these improvements despite many constraints. Typical improvements include mobile racks, simple workstation changes, screening hazards, better welfare facilities and teamwork arrangements. In view of the complex circumstances of work-related health risks, it is important to know whether a low-cost strategy can advance risk reduction practices effectively and what support measures are necessary. It is confirmed that the strategy can overcome related constraints through its advantages. Main advantages lie in (a) the facilitation of improved practices in multiple technical areas, (b) the strengthening of realistic stepwise risk reduction, and (c) the enhanced multiplier effects through training of local trainers. Action-oriented risk assessment tools, such as action checklists and low-cost improvement guides, can encourage risk-reducing measures adjusted to each local situation. It is suggested to spread the low-cost risk reduction strategy for improving small workplaces in diversified settings with the support of these locally tailored tools.

  6. Laser Pointers: Low-Cost, Low-Tech Innovative, Interactive Instruction Tool

    Science.gov (United States)

    Zdravkovska, Nevenka; Cech, Maureen; Beygo, Pinar; Kackley, Bob

    2010-01-01

    This paper discusses the use of laser pointers at the Engineering and Physical Sciences Library, University of Maryland, College Park, as a personal response system (PRS) tool to encourage student engagement in and interactivity with one-shot, lecture-based information literacy sessions. Unlike more sophisticated personal response systems like…

  7. Open-Source 3-D Platform for Low-Cost Scientific Instrument Ecosystem.

    Science.gov (United States)

    Zhang, C; Wijnen, B; Pearce, J M

    2016-08-01

    The combination of open-source software and hardware provides technically feasible methods to create low-cost, highly customized scientific research equipment. Open-source 3-D printers have proven useful for fabricating scientific tools. Here the capabilities of an open-source 3-D printer are expanded to become a highly flexible scientific platform. An automated low-cost 3-D motion control platform is presented that has the capacity to perform scientific applications, including (1) 3-D printing of scientific hardware; (2) laboratory auto-stirring, measuring, and probing; (3) automated fluid handling; and (4) shaking and mixing. The open-source 3-D platform not only facilities routine research while radically reducing the cost, but also inspires the creation of a diverse array of custom instruments that can be shared and replicated digitally throughout the world to drive down the cost of research and education further. © 2016 Society for Laboratory Automation and Screening.

  8. Validation of an effective, low cost, Free/open access 3D-printed stethoscope

    Science.gov (United States)

    Pavlosky, Alexander; Glauche, Jennifer; Chambers, Spencer; Al-Alawi, Mahmoud; Yanev, Kliment

    2018-01-01

    The modern acoustic stethoscope is a useful clinical tool used to detect subtle, pathological changes in cardiac, pulmonary and vascular sounds. Currently, brand-name stethoscopes are expensive despite limited innovations in design or fabrication in recent decades. Consequently, the high cost of high quality, brand name models serves as a barrier to clinicians practicing in various settings, especially in low- and middle-income countries. In this publication, we describe the design and validation of a low-cost open-access (Free/Libre) 3D-printed stethoscope which is comparable to the Littmann Cardiology III for use in low-access clinics. PMID:29538426

  9. Low Cost ZigBee Protocol Based Laboratory Platforms

    Directory of Open Access Journals (Sweden)

    Alvaro Romero-Acero

    2013-11-01

    Full Text Available This paper presents a low cost wireless communication platform, based on the ZigBee protocol. It is designed with the purpose to strengthen the use of information technology in the classroom. Guides laboratory practices are focused on developing undergraduate engineering students to the area of telecommunications. The platform structure is composed of: Labs custom designed, web tools embedded wireless communication system for data acquisition in real time, and the Human Machine Interface (HMI, which records analog data and digital. 

  10. Hidden costs of low-cost screening mammography

    International Nuclear Information System (INIS)

    Cyrlak, D.

    1987-01-01

    Twenty-two hundred women in Orange County, California, took part in a low-cost mammography screening project sponsored by the American Cancer Society and the KCBS-TV. Patients were followed up by telephone and questioned about actual costs incurred as a result of screening mammography, including costs of repeated and follow-up mammograms, US examinations and surgical consultations. The total number of biopsies, cancers found, and the costs involved were investigated. The authors' results suggest that particularly in centers with a high positive call rate, the cost of screening mammograms accounts for only a small proportion of the medical costs

  11. Rapid and Low-cost Prototyping of Medical Devices Using 3D Printed Molds for Liquid Injection Molding

    Science.gov (United States)

    Chung, Philip; Heller, J. Alex; Etemadi, Mozziyar; Ottoson, Paige E.; Liu, Jonathan A.; Rand, Larry; Roy, Shuvo

    2014-01-01

    Biologically inert elastomers such as silicone are favorable materials for medical device fabrication, but forming and curing these elastomers using traditional liquid injection molding processes can be an expensive process due to tooling and equipment costs. As a result, it has traditionally been impractical to use liquid injection molding for low-cost, rapid prototyping applications. We have devised a method for rapid and low-cost production of liquid elastomer injection molded devices that utilizes fused deposition modeling 3D printers for mold design and a modified desiccator as an injection system. Low costs and rapid turnaround time in this technique lower the barrier to iteratively designing and prototyping complex elastomer devices. Furthermore, CAD models developed in this process can be later adapted for metal mold tooling design, enabling an easy transition to a traditional injection molding process. We have used this technique to manufacture intravaginal probes involving complex geometries, as well as overmolding over metal parts, using tools commonly available within an academic research laboratory. However, this technique can be easily adapted to create liquid injection molded devices for many other applications. PMID:24998993

  12. Lives Saved Tool (LiST) costing: a module to examine costs and prioritize interventions.

    Science.gov (United States)

    Bollinger, Lori A; Sanders, Rachel; Winfrey, William; Adesina, Adebiyi

    2017-11-07

    Achieving the Sustainable Development Goals will require careful allocation of resources in order to achieve the highest impact. The Lives Saved Tool (LiST) has been used widely to calculate the impact of maternal, neonatal and child health (MNCH) interventions for program planning and multi-country estimation in several Lancet Series commissions. As use of the LiST model increases, many have expressed a desire to cost interventions within the model, in order to support budgeting and prioritization of interventions by countries. A limited LiST costing module was introduced several years ago, but with gaps in cost types. Updates to inputs have now been added to make the module fully functional for a range of uses. This paper builds on previous work that developed an initial version of the LiST costing module to provide costs for MNCH interventions using an ingredients-based costing approach. Here, we update in 2016 the previous econometric estimates from 2013 with newly-available data and also include above-facility level costs such as program management. The updated econometric estimates inform percentages of intervention-level costs for some direct costs and indirect costs. These estimates add to existing values for direct cost requirements for items such as drugs and supplies and required provider time which were already available in LiST Costing. Results generated by the LiST costing module include costs for each intervention, as well as disaggregated costs by intervention including drug and supply costs, labor costs, other recurrent costs, capital costs, and above-service delivery costs. These results can be combined with mortality estimates to support prioritization of interventions by countries. The LiST costing module provides an option for countries to identify resource requirements for scaling up a maternal, neonatal, and child health program, and to examine the financial impact of different resource allocation strategies. It can be a useful tool for

  13. Lives Saved Tool (LiST costing: a module to examine costs and prioritize interventions

    Directory of Open Access Journals (Sweden)

    Lori A. Bollinger

    2017-11-01

    Full Text Available Abstract Background Achieving the Sustainable Development Goals will require careful allocation of resources in order to achieve the highest impact. The Lives Saved Tool (LiST has been used widely to calculate the impact of maternal, neonatal and child health (MNCH interventions for program planning and multi-country estimation in several Lancet Series commissions. As use of the LiST model increases, many have expressed a desire to cost interventions within the model, in order to support budgeting and prioritization of interventions by countries. A limited LiST costing module was introduced several years ago, but with gaps in cost types. Updates to inputs have now been added to make the module fully functional for a range of uses. Methods This paper builds on previous work that developed an initial version of the LiST costing module to provide costs for MNCH interventions using an ingredients-based costing approach. Here, we update in 2016 the previous econometric estimates from 2013 with newly-available data and also include above-facility level costs such as program management. The updated econometric estimates inform percentages of intervention-level costs for some direct costs and indirect costs. These estimates add to existing values for direct cost requirements for items such as drugs and supplies and required provider time which were already available in LiST Costing. Results Results generated by the LiST costing module include costs for each intervention, as well as disaggregated costs by intervention including drug and supply costs, labor costs, other recurrent costs, capital costs, and above-service delivery costs. These results can be combined with mortality estimates to support prioritization of interventions by countries. Conclusions The LiST costing module provides an option for countries to identify resource requirements for scaling up a maternal, neonatal, and child health program, and to examine the financial impact of different

  14. Informed public choices for low-carbon electricity portfolios using a computer decision tool.

    Science.gov (United States)

    Mayer, Lauren A Fleishman; Bruine de Bruin, Wändi; Morgan, M Granger

    2014-04-01

    Reducing CO2 emissions from the electricity sector will likely require policies that encourage the widespread deployment of a diverse mix of low-carbon electricity generation technologies. Public discourse informs such policies. To make informed decisions and to productively engage in public discourse, citizens need to understand the trade-offs between electricity technologies proposed for widespread deployment. Building on previous paper-and-pencil studies, we developed a computer tool that aimed to help nonexperts make informed decisions about the challenges faced in achieving a low-carbon energy future. We report on an initial usability study of this interactive computer tool. After providing participants with comparative and balanced information about 10 electricity technologies, we asked them to design a low-carbon electricity portfolio. Participants used the interactive computer tool, which constrained portfolio designs to be realistic and yield low CO2 emissions. As they changed their portfolios, the tool updated information about projected CO2 emissions, electricity costs, and specific environmental impacts. As in the previous paper-and-pencil studies, most participants designed diverse portfolios that included energy efficiency, nuclear, coal with carbon capture and sequestration, natural gas, and wind. Our results suggest that participants understood the tool and used it consistently. The tool may be downloaded from http://cedmcenter.org/tools-for-cedm/informing-the-public-about-low-carbon-technologies/ .

  15. Low-cost high purity production

    Science.gov (United States)

    Kapur, V. K.

    1978-01-01

    Economical process produces high-purity silicon crystals suitable for use in solar cells. Reaction is strongly exothermic and can be initiated at relatively low temperature, making it potentially suitable for development into low-cost commercial process. Important advantages include exothermic character and comparatively low process temperatures. These could lead to significant savings in equipment and energy costs.

  16. How to Mobilize your Library at Low Cost

    Directory of Open Access Journals (Sweden)

    Marta Abarca Villoldo

    2012-09-01

    tools are available free of charge. In other words, these are low-cost tools that offer high returns to the user.

  17. An Evaluation of the Automated Cost Estimating Integrated Tools (ACEIT) System

    Science.gov (United States)

    1989-09-01

    C~4p DTIC S ELECTE fl JAN12 19 .1R ~OF S%. B -U AN EVALUATION OF THE AUTOMATED COST ESTIMATING INTEGRATED TOOLS ( ACEIT ) SYSTEM THESIS Caroline L...Ohio go 91 022 AFIT/GCA/LSQ/89S-5 AN EVALUATION OF THE AUTOMATED COST ESTIMATING INTEGRATED TOOLS ( ACEIT ) SYSTEM THESIS Caroline L. Hanson Major, USAF...Department of Defense. AFIT/GCA/LSQ/89S-5 AN EVALUATION OF THE AUTOMATED COST ESTIMATING INTEGRATED TOOLS ( ACEIT ) SYSTEM THESIS Presented to the

  18. Costing Tool for International Cancer Registries

    Centers for Disease Control (CDC) Podcasts

    2016-11-21

    A health economist at CDC talks about a new tool for estimating how much it costs to run cancer registries in developing countries.  Created: 11/21/2016 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 11/21/2016.

  19. A low-cost, modular, microwave-linked, color TV inspection system

    International Nuclear Information System (INIS)

    Panda, N.C.

    1991-01-01

    This paper reports that many custom-built radiation-shielded CCTV inspection systems for nuclear facilities are available in the market. This author, however, could find no reference to units using low-cost nodular technology for wireless transmission and control of color CCTV signals in radiation environments. The system that was developed is a process control observation tool geared toward identifying locations ad volumes of accumulated in-cell solids. It also performs remote integrity assessments of tanks and pipe routings that are required by regulatory agencies. System highlights are: microwave transmission of video and control signals, low cost, low maintenance, and modular design. Use of standard components enables easy exchange of modules. Microwave transmission resolved the complications of a wired system while increasing reliability and safety. The video image is created by the remote in-cell color TV camera and transmitted by microwave out of the cell to TV monitors at consoles in non-radiation zones

  20. Investigation of Low Cost Sensor-Based Leak Detection System for Fence Line Applications

    Science.gov (United States)

    With recent technological advances, low-cost time-resolved sensors may become effective tools to support time-integrated passive sampling strategies by helping to decipher origin of emissions in real-time. As part of the Petroleum Refinery Risk and Technology Review, New Source ...

  1. Pointo - a Low Cost Solution to Point Cloud Processing

    Science.gov (United States)

    Houshiar, H.; Winkler, S.

    2017-11-01

    With advance in technology access to data especially 3D point cloud data becomes more and more an everyday task. 3D point clouds are usually captured with very expensive tools such as 3D laser scanners or very time consuming methods such as photogrammetry. Most of the available softwares for 3D point cloud processing are designed for experts and specialists in this field and are usually very large software packages containing variety of methods and tools. This results in softwares that are usually very expensive to acquire and also very difficult to use. Difficulty of use is caused by complicated user interfaces that is required to accommodate a large list of features. The aim of these complex softwares is to provide a powerful tool for a specific group of specialist. However they are not necessary required by the majority of the up coming average users of point clouds. In addition to complexity and high costs of these softwares they generally rely on expensive and modern hardware and only compatible with one specific operating system. Many point cloud customers are not point cloud processing experts or willing to spend the high acquisition costs of these expensive softwares and hardwares. In this paper we introduce a solution for low cost point cloud processing. Our approach is designed to accommodate the needs of the average point cloud user. To reduce the cost and complexity of software our approach focuses on one functionality at a time in contrast with most available softwares and tools that aim to solve as many problems as possible at the same time. Our simple and user oriented design improve the user experience and empower us to optimize our methods for creation of an efficient software. In this paper we introduce Pointo family as a series of connected softwares to provide easy to use tools with simple design for different point cloud processing requirements. PointoVIEWER and PointoCAD are introduced as the first components of the Pointo family to provide a

  2. J3Gen: A PRNG for Low-Cost Passive RFID

    Directory of Open Access Journals (Sweden)

    Jordi Herrera-Joancomartí

    2013-03-01

    Full Text Available Pseudorandom number generation (PRNG is the main security tool in low-cost passive radio-frequency identification (RFID technologies, such as EPC Gen2. We present a lightweight PRNG design for low-cost passive RFID tags, named J3Gen. J3Gen is based on a linear feedback shift register (LFSR configured with multiple feedback polynomials. The polynomials are alternated during the generation of sequences via a physical source of randomness. J3Gen successfully handles the inherent linearity of LFSR based PRNGs and satisfies the statistical requirements imposed by the EPC Gen2 standard. A hardware implementation of J3Gen is presented and evaluated with regard to different design parameters, defining the key-equivalence security and nonlinearity of the design. The results of a SPICE simulation confirm the power-consumption suitability of the proposal.

  3. Vector Production in an Academic Environment: A Tool to Assess Production Costs

    Science.gov (United States)

    Boeke, Aaron; Doumas, Patrick; Reeves, Lilith; McClurg, Kyle; Bischof, Daniela; Sego, Lina; Auberry, Alisha; Tatikonda, Mohan

    2013-01-01

    Abstract Generating gene and cell therapy products under good manufacturing practices is a complex process. When determining the cost of these products, researchers must consider the large number of supplies used for manufacturing and the personnel and facility costs to generate vector and maintain a cleanroom facility. To facilitate cost estimates, the Indiana University Vector Production Facility teamed with the Indiana University Kelley School of Business to develop a costing tool that, in turn, provides pricing. The tool is designed in Microsoft Excel and is customizable to meet the needs of other core facilities. It is available from the National Gene Vector Biorepository. The tool allows cost determinations using three different costing methods and was developed in an effort to meet the A21 circular requirements for U.S. core facilities performing work for federally funded projects. The costing tool analysis reveals that the cost of vector production does not have a linear relationship with batch size. For example, increasing the production from 9 to18 liters of a retroviral vector product increases total costs a modest 1.2-fold rather than doubling in total cost. The analysis discussed in this article will help core facilities and investigators plan a cost-effective strategy for gene and cell therapy production. PMID:23360377

  4. A Low-Cost Sensing System for Cooperative Air Quality Monitoring in Urban Areas

    Directory of Open Access Journals (Sweden)

    Simone Brienza

    2015-05-01

    Full Text Available Air quality in urban areas is a very important topic as it closely affects the health of citizens. Recent studies highlight that the exposure to polluted air can increase the incidence of diseases and deteriorate the quality of life. Hence, it is necessary to develop tools for real-time air quality monitoring, so as to allow appropriate and timely decisions. In this paper, we present uSense, a low-cost cooperative monitoring tool that allows knowing, in real-time, the concentrations of polluting gases in various areas of the city. Specifically, users monitor the areas of their interest by deploying low-cost and low-power sensor nodes. In addition, they can share the collected data following a social networking approach. uSense has been tested through an in-field experimentation performed in different areas of a city. The obtained results are in line with those provided by the local environmental control authority and show that uSense can be profitably used for air quality monitoring.

  5. Estimating costs of care for meningitis infections in low- and middle-income countries.

    Science.gov (United States)

    Portnoy, Allison; Jit, Mark; Lauer, Jeremy; Blommaert, Adriaan; Ozawa, Sachiko; Stack, Meghan; Murray, Jillian; Hutubessy, Raymond

    2015-05-07

    Meningitis infections are often associated with high mortality and risk of sequelae. The costs of treatment and care for meningitis are a great burden on health care systems, particularly in resource-limited settings. The objective of this study is to review data on the costs of care for meningitis in low- and middle-income countries, as well as to show how results could be extrapolated to countries without sound data. We conducted a systematic review of the literature from six databases to identify studies examining the cost of care in low- and middle-income countries for all age groups with suspected, probable, or confirmed meningitis. We extracted data on treatment costs and sequelae by infectious agent and/or pathogen, where possible. Using multiple regression analysis, a relationship between hospital costs and associated determinants was investigated in order to predict costs in countries with missing data. This relationship was used to predict treatment costs for all 144 low- and middle-income countries. The methodology of conducting a systematic review, extrapolating, and setting up a standard database can be used as a tool to inform cost-effectiveness analyses in situations where cost of care data are poor. Both acute and long-term costs of meningitis could be extrapolated to countries without reliable data. Although only bacterial causes of meningitis can be vaccine-preventable, a better understanding of the treatment costs for meningitis is crucial for low- and middle-income countries to assess the cost-effectiveness of proposed interventions in their country. This cost information will be important as inputs in future cost-effectiveness studies, particularly for vaccines. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. Cost analysis and estimating tools and techniques

    CERN Document Server

    Nussbaum, Daniel

    1990-01-01

    Changes in production processes reflect the technological advances permeat­ ing our products and services. U. S. industry is modernizing and automating. In parallel, direct labor is fading as the primary cost driver while engineering and technology related cost elements loom ever larger. Traditional, labor-based ap­ proaches to estimating costs are losing their relevance. Old methods require aug­ mentation with new estimating tools and techniques that capture the emerging environment. This volume represents one of many responses to this challenge by the cost analysis profession. The Institute of Cost Analysis (lCA) is dedicated to improving the effective­ ness of cost and price analysis and enhancing the professional competence of its members. We encourage and promote exchange of research findings and appli­ cations between the academic community and cost professionals in industry and government. The 1990 National Meeting in Los Angeles, jointly spo~sored by ICA and the National Estimating Society (NES),...

  7. Low cost solar air heater

    International Nuclear Information System (INIS)

    Gill, R.S.; Singh, Sukhmeet; Singh, Parm Pal

    2012-01-01

    Highlights: ► Single glazed low cost solar air heater is more efficient during summer while double glazed is better in winter. ► For the same initial investment, low cost solar air heaters collect more energy than packed bed solar air heater. ► During off season low cost solar air heater can be stored inside as it is light in weight. - Abstract: Two low cost solar air heaters viz. single glazed and double glazed were designed, fabricated and tested. Thermocole, ultraviolet stabilised plastic sheet, etc. were used for fabrication to reduce the fabrication cost. These were tested simultaneously at no load and with load both in summer and winter seasons along with packed bed solar air heater using iron chips for absorption of radiation. The initial costs of single glazed and double glazed are 22.8% and 26.8% of the initial cost of packed bed solar air heater of the same aperture area. It was found that on a given day at no load, the maximum stagnation temperatures of single glazed and double glazed solar air heater were 43.5 °C and 62.5 °C respectively. The efficiencies of single glazed, double glazed and packed bed solar air heaters corresponding to flow rate of 0.02 m 3 /s-m 2 were 30.29%, 45.05% and 71.68% respectively in winter season. The collector efficiency factor, heat removal factor based on air outlet temperature and air inlet temperature for three solar air heaters were also determined.

  8. No CostLow Cost Compressed Air System Optimization in Industry

    Science.gov (United States)

    Dharma, A.; Budiarsa, N.; Watiniasih, N.; Antara, N. G.

    2018-04-01

    Energy conservation is a systematic, integrated of effort, in order to preserve energy sources and improve energy utilization efficiency. Utilization of energy in efficient manner without reducing the energy usage it must. Energy conservation efforts are applied at all stages of utilization, from utilization of energy resources to final, using efficient technology, and cultivating an energy-efficient lifestyle. The most common way is to promote energy efficiency in the industry on end use and overcome barriers to achieve such efficiency by using system energy optimization programs. The facts show that energy saving efforts in the process usually only focus on replacing tools and not an overall system improvement effort. In this research, a framework of sustainable energy reduction work in companies that have or have not implemented energy management system (EnMS) will be conducted a systematic technical approach in evaluating accurately a compressed-air system and potential optimization through observation, measurement and verification environmental conditions and processes, then processing the physical quantities of systems such as air flow, pressure and electrical power energy at any given time measured using comparative analysis methods in this industry, to provide the potential savings of energy saving is greater than the component approach, with no cost to the lowest cost (no cost - low cost). The process of evaluating energy utilization and energy saving opportunities will provide recommendations for increasing efficiency in the industry and reducing CO2 emissions and improving environmental quality.

  9. Additively Manufactured Low Cost Upper Stage Combustion Chamber

    Science.gov (United States)

    Protz, Christopher; Cooper, Ken; Ellis, David; Fikes, John; Jones, Zachary; Kim, Tony; Medina, Cory; Taminger, Karen; Willingham, Derek

    2016-01-01

    Over the past two years NASA's Low Cost Upper Stage Propulsion (LCUSP) project has developed Additive Manufacturing (AM) technologies and design tools aimed at reducing the costs and manufacturing time of regeneratively cooled rocket engine components. High pressure/high temperature combustion chambers and nozzles must be regeneratively cooled to survive their operating environment, causing their design fabrication to be costly and time consuming due to the number of individual steps and different processes required. Under LCUSP, AM technologies in Sintered Laser Melting (SLM) GRCop-84 and Electron Beam Freeform Fabrication (EBF3) Inconel 625 have been significantly advanced, allowing the team to successfully fabricate a 25k-class regenerative chamber. Estimates of the costs and schedule of future builds indicate cost reductions and significant schedule reductions will be enabled by this technology. Characterization of the microstructural and mechanical properties of the SLM-produced GRCop-84, EBF3 Inconel 625 and the interface layer between the two has been performed and indicates the properties will meet the design requirements. The LCUSP chamber is to be tested with a previously demonstrated SLM injector in order to advance the Technology Readiness Level (TRL) and demonstrate the capability of the application of these processes. NASA is advancing these technologies to reduce cost and schedule for future engine applications and commercial needs.

  10. Water Level Loggers as a Low-Cost Tool for Monitoring of Stormwater Control Measures

    Directory of Open Access Journals (Sweden)

    Laura Toran

    2016-08-01

    Full Text Available Stormwater control measures (SCMs are a key component of watershed health in urbanized areas. SCMs are used to increase infiltration and reduce discharge to streams or storm sewer systems during rain events. Monitoring is important for the evaluation of design and causes of failure in SCMs. However, the expense of monitoring means it is not always included in stormwater control planning. This study shows how low-cost water level loggers can be used to answer certain questions about SCM performance. Five case studies are presented that use water level loggers to evaluate the overflow of basins, compare a traditional stormpipe trench with an infiltration trench, monitor timing of blue roof storage, show the effects of retrofitting a basin, and provide long term performance data. Water level loggers can be used to answer questions about the timing and location of stormwater overflows, which helps to evaluate the effectiveness of SCMs. More expensive monitoring and modeling can be used as a follow up if needed to more thoroughly assess a site. Nonetheless, low-cost monitoring can be a first step in identifying sites that need improvement or additional monitoring.

  11. Diagnosis of cattle diseases endemic to sub-Saharan Africa: evaluating a low cost decision support tool in use by veterinary personnel.

    Directory of Open Access Journals (Sweden)

    Mark C Eisler

    Full Text Available BACKGROUND: Diagnosis is key to control and prevention of livestock diseases. In areas of sub-Saharan Africa where private practitioners rarely replace Government veterinary services reduced in effectiveness by structural adjustment programmes, those who remain lack resources for diagnosis and might benefit from decision support. METHODOLOGY/PRINCIPAL FINDINGS: We evaluated whether a low-cost diagnostic decision support tool would lead to changes in clinical diagnostic practice by fifteen veterinary and animal health officers undertaking primary animal healthcare in Uganda. The eight diseases covered by the tool included 98% of all bovine diagnoses made before or after its introduction. It may therefore inform proportional morbidity in the area; breed, age and geographic location effects were consistent with current epidemiological understanding. Trypanosomosis, theileriosis, anaplasmosis, and parasitic gastroenteritis were the most common conditions among 713 bovine clinical cases diagnosed prior to introduction of the tool. Thereafter, in 747 bovine clinical cases estimated proportional morbidity of fasciolosis doubled, while theileriosis and parasitic gastroenteritis were diagnosed less commonly and the average number of clinical signs increased from 3.5 to 4.9 per case, with 28% of cases reporting six or more signs compared to 3% beforehand. Anaemia/pallor, weakness and staring coat contributed most to this increase, approximately doubling in number and were recorded in over half of all cases. Finally, although lack of a gold standard hindered objective assessment of whether the tool improved the reliability of diagnosis, informative concordance and misclassification matrices yielded useful insights into its role in the diagnostic process. CONCLUSIONS/SIGNIFICANCE: The diagnostic decision support tool covered the majority of diagnoses made before or after its introduction, leading to a significant increase in the number of clinical signs

  12. Air Traffic Management Cost Assessment Tool, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — The Robust Analytics Air Traffic Management Cost Assessment Tool (ACAT) provides the comprehensive capability to analyze the impacts of NASA air traffic management...

  13. A Cost Simulation Tool for Estimating the Cost of Operating Government Owned and Operated Ships

    Science.gov (United States)

    1994-09-01

    Horngren , C.T., Foster, G., Datar, S.M., Cost Accounting : A Management Emphasis, Prentice-Hall, Englewood Cliffs, NJ, 1994 IBM Corporation, A Graphical...4. TITLE AND SUBTITLE A COST SIMULATION TOOL FOR 5. FUNDING NUMBERS ESTIMATING THE COST OF OPERATING GOVERNMENT OWNED AND OPERATED SHIPS 6. AUTHOR( S ...normally does not present a problem to the accounting department. The final category, the cost of operating the government owned and operated ships is

  14. Low energy, low cost, efficient CO{sub 2} capture

    Energy Technology Data Exchange (ETDEWEB)

    Michael C. Trachtenberg; Lihong Bao; David A. Smith; Remy Dumortier [Carbozyme, Inc., Monmouth Junction, NJ (United States)

    2006-07-01

    This paper discusses the development and some characteristics of a new, enzyme-based, contained liquid membrane contactor to capture CO{sub 2}. The enzyme carbonic anhydrase catalyzes the removal of CO{sub 2} while the membrane contactor increases the surface area to allow the reduction of the size of the system. The modular system design is easily scaled to any required size reducing the investment costs. The system captures CO{sub 2} at a low energy and low cost promising to be a cost effective technology for CO{sub 2} capture. 5 refs., 7 figs.

  15. A Cost-Effectiveness Tool for Informing Policies on Zika Virus Control.

    Directory of Open Access Journals (Sweden)

    Jorge A Alfaro-Murillo

    2016-05-01

    Full Text Available As Zika virus continues to spread, decisions regarding resource allocations to control the outbreak underscore the need for a tool to weigh policies according to their cost and the health burden they could avert. For example, to combat the current Zika outbreak the US President requested the allocation of $1.8 billion from Congress in February 2016.Illustrated through an interactive tool, we evaluated how the number of Zika cases averted, the period during pregnancy in which Zika infection poses a risk of microcephaly, and probabilities of microcephaly and Guillain-Barré Syndrome (GBS impact the cost at which an intervention is cost-effective. From Northeast Brazilian microcephaly incidence data, we estimated the probability of microcephaly in infants born to Zika-infected women (0.49% to 2.10%. We also estimated the probability of GBS arising from Zika infections in Brazil (0.02% to 0.06% and Colombia (0.08%. We calculated that each microcephaly and GBS case incurs the loss of 29.95 DALYs and 1.25 DALYs per case, as well as direct medical costs for Latin America and the Caribbean of $91,102 and $28,818, respectively. We demonstrated the utility of our cost-effectiveness tool with examples evaluating funding commitments by Costa Rica and Brazil, the US presidential proposal, and the novel approach of genetically modified mosquitoes. Our analyses indicate that the commitments and the proposal are likely to be cost-effective, whereas the cost-effectiveness of genetically modified mosquitoes depends on the country of implementation.Current estimates from our tool suggest that the health burden from microcephaly and GBS warrants substantial expenditures focused on Zika virus control. Our results justify the funding committed in Costa Rica and Brazil and many aspects of the budget outlined in the US president's proposal. As data continue to be collected, new parameter estimates can be customized in real-time within our user-friendly tool to provide

  16. Low-cost carriers fare competition effect

    NARCIS (Netherlands)

    Carmona Benitez, R.B.; Lodewijks, G.

    2010-01-01

    This paper examines the effects that low-cost carriers (LCC’s) produce when entering new routes operated only by full-service carriers (FSC’s) and routes operated by low-cost carriers in competition with full-service carriers. A mathematical model has been developed to determine what routes should

  17. Low-Cost Spectral Sensor Development Description.

    Energy Technology Data Exchange (ETDEWEB)

    Armijo, Kenneth Miguel; Yellowhair, Julius

    2014-11-01

    Solar spectral data for all parts of the US is limited due in part to the high cost of commercial spectrometers. Solar spectral information is necessary for accurate photovoltaic (PV) performance forecasting, especially for large utility-scale PV installations. A low-cost solar spectral sensor would address the obstacles and needs. In this report, a novel low-cost, discrete- band sensor device, comprised of five narrow-band sensors, is described. The hardware is comprised of commercial-off-the-shelf components to keep the cost low. Data processing algorithms were developed and are being refined for robustness. PV module short-circuit current ( I sc ) prediction methods were developed based on interaction-terms regression methodology and spectrum reconstruction methodology for computing I sc . The results suggest the computed spectrum using the reconstruction method agreed well with the measured spectrum from the wide-band spectrometer (RMS error of 38.2 W/m 2 -nm). Further analysis of computed I sc found a close correspondence of 0.05 A RMS error. The goal is for ubiquitous adoption of the low-cost spectral sensor in solar PV and other applications such as weather forecasting.

  18. Experiences from implementing a low cost configurator

    DEFF Research Database (Denmark)

    Svensson, Carsten

    2002-01-01

    of the cost of producing the specifications needed for production. Not only are the specifications becoming more complex, but also at the same time the inquiry to order ration is falling. This motivates the search for tools that can help to streamline the specification system and thereby reduce the cost...

  19. Developing a low-cost open-source CTD for research and outreach

    Science.gov (United States)

    Thaler, A. D.; Sturdivant, K.

    2013-12-01

    Developing a low-cost open-source CTD for research and outreach Andrew David Thaler and Kersey Sturdivant Conductivity, temperature, and depth (CTD). With these three measurements, marine scientists can unlock ocean patterns hidden beneath the waves. The ocean is not uniform, it its filled with swirling eddies, temperature boundaries, layers of high and low salinity, changing densities, and many other physical characteristics. To reveal these patterns, oceanographers use a tool called the CTD. A CTD is found on almost every major research vessel. Rare is the scientific expedition-whether it be coastal work in shallow estuaries or journeys to the deepest ocean trenches-that doesn't begin with the humble CTD cast. The CTD is not cheap. Commercial CTD's start at more the 5,000 and can climb as high as 25,000 or more. We believe that the prohibitive cost of a CTD is an unacceptable barrier to open science. The price tag excludes individuals and groups who lack research grants or significant private funds from conducting oceanographic research. We want to make this tool-the workhorse of oceanographic research-available to anyone with an interest in the oceans. The OpenCTD is a low-cost, open-source CTD suitable for both educators and scientists. The platform is built using readily available parts and is powered by an Arduino-based microcontroller. Our goal is to create a device that is accurate enough to be used for scientific research and can be constructed for less than $200. Source codes, circuit diagrams, and building plans will be freely available. The final instrument will be effective to 200 meters depth. Why 200 meters? For many coastal regions, 200 meters of water depth covers the majority of the ocean that is accessible by small boat. The OpenCTD is targeted to people working in this niche, where entire research projects can be conducted for less than the cost of a commercial CTD. However, the Open CTD is scalable, and anyone with the inclination can adapt our

  20. Scale models: A proven cost-effective tool for outage planning

    Energy Technology Data Exchange (ETDEWEB)

    Lee, R. [Commonwealth Edison Co., Morris, IL (United States); Segroves, R. [Sargent & Lundy, Chicago, IL (United States)

    1995-03-01

    As generation costs for operating nuclear stations have risen, more nuclear utilities have initiated efforts to improve cost effectiveness. Nuclear plant owners are also being challenged with lower radiation exposure limits and new revised radiation protection related regulations (10 CFR 20), which places further stress on their budgets. As source term reduction activities continue to lower radiation fields, reducing the amount of time spent in radiation fields becomes one of the most cost-effective ways of reducing radiation exposure. An effective approach for minimizing time spent in radiation areas is to use a physical scale model for worker orientation planning and monitoring maintenance, modifications, and outage activities. To meet the challenge of continued reduction in the annual cumulative radiation exposures, new cost-effective tools are required. One field-tested and proven tool is the physical scale model.

  1. Low-cost electron-gun pulser for table-top maser experiments

    Science.gov (United States)

    Grinberg, V.; Jerby, E.; Shahadi, A.

    1995-04-01

    A simple 10 kV electron-gun pulser for small-scale maser experiments is presented. This low-cost pulser has operated successfully in various table-top cyclotron-resonance maser (CRM) and free-electron maser (FEM) experiments. It consists of a low-voltage capacitor bank, an SCR control circuit and a transformer bank (car ignition coils) connected directly to the e-gun. The pulser produces a current of 3 A at 10 kV voltage in a Gaussian like shape of 1 ms pulse width. The voltage sweep during the pulse provides a useful tool to locate resonances of CRM and FEM interactions. Analytical expressions for the pulser design and experimental measurements are presented.

  2. Development of the oil spill response cost-effectiveness analytical tool

    International Nuclear Information System (INIS)

    Etkin, D.S.; Welch, J.

    2005-01-01

    Decision-making during oil spill response operations or contingency planning requires balancing the need to remove as much oil as possible from the environment with the desire to minimize the impact of response operations on the environment they are intended to protect. This paper discussed the creation of a computer tool developed to help in planning and decision-making during response operations. The Oil Spill Response Cost-Effectiveness Analytical Tool (OSRCEAT) was developed to compare the costs of response with the benefits of response in both hypothetical and actual oil spills. The computer-based analytical tool can assist responders and contingency planners in decision-making processes as well as act as a basis of discussion in the evaluation of response options. Using inputs on spill parameters, location and response options, OSRCEAT can calculate response cost, costs of environmental and socioeconomic impacts of the oil spill and response impacts. Oil damages without any response are contrasted to oil damages with response, with expected improvements. Response damages are subtracted from the difference in damages with and without response in order to derive a more accurate response benefit. An OSRCEAT user can test various response options to compare potential benefits in order to maximize response benefit. OSRCEAT is best used to compare and contrast the relative benefits and costs of various response options. 50 refs., 19 tabs., 2 figs

  3. Strategies to fight low-cost rivals.

    Science.gov (United States)

    Kumar, Nirmalya

    2006-12-01

    Companies find it challenging and yet strangely reassuring to take on opponents whose strategies, strengths, and weaknesses resemble their own. Their obsession with familiar rivals, however, has blinded them to threats from disruptive, low-cost competitors. Successful price warriors, such as the German retailer Aldi, are changing the nature of competition by employing several tactics: focusing on just one or a few consumer segments, delivering the basic product or providing one benefit better than rivals do, and backing low prices with superefficient operations. Ignoring cutprice rivals is a mistake because they eventually force companies to vacate entire market segments. Price wars are not the answer, either: Slashing prices usually lowers profits for incumbents without driving the low-cost entrants out of business. Companies take various approaches to competing against cut-price players. Some differentiate their products--a strategy that works only in certain circumstances. Others launch low-cost businesses of their own, as many airlines did in the 1990s--a so-called dual strategy that succeeds only if companies can generate synergies between the existing businesses and the new ventures, as the financial service providers HSBC and ING did. Without synergies, corporations are better off trying to transform themselves into low-cost players, a difficult feat that Ryanair accomplished in the 1990s, or into solution providers. There will always be room for both low-cost and value-added players. How much room each will have depends not only on the industry and customers' preferences, but also on the strategies traditional businesses deploy.

  4. Digital Preservation Tools for Repository Managers 2: institutional and lifecycle preservation costs

    OpenAIRE

    Hitchcock, Steve; Beagrie, Neil; Hole, Brian

    2010-01-01

    The 5-module JISC KeepIt course on Digital Preservation Tools for Repository Managers was designed by repository managers. Each module consists of a mix of short presentations and hands-on exercises to learn about the basics and gain practice with each of the tools covered. Module 2 covers lifecycle costs for managing digital objects, based on the LIFE approach, and institutional costs. Tools include Keeping Research Data Safe (KRDS) a model, method and survey for assessing the institutional ...

  5. Low Cost Benefit Suggestions.

    Science.gov (United States)

    Doyel, Hoyt W.; McMillan, John D.

    1980-01-01

    Outlines eight low-cost employee benefits and summarizes their relative advantages. The eight include a stock ownership program, a sick leave pool, flexible working hours, production incentives, and group purchase plans. (IRT)

  6. Low Cost, Low Power, High Sensitivity Magnetometer

    Science.gov (United States)

    2008-12-01

    which are used to measure the small magnetic signals from brain. Other types of vector magnetometers are fluxgate , coil based, and magnetoresistance...concentrator with the magnetometer currently used in Army multimodal sensor systems, the Brown fluxgate . One sees the MEMS fluxgate magnetometer is...Guedes, A.; et al., 2008: Hybrid - LOW COST, LOW POWER, HIGH SENSITIVITY MAGNETOMETER A.S. Edelstein*, James E. Burnette, Greg A. Fischer, M.G

  7. Low-cost satellite mechanical design and construction

    Science.gov (United States)

    Boisjolie-Gair, Nathaniel; Straub, Jeremy

    2017-05-01

    This paper presents a discussion of techniques for low-cost design and construction of a CubeSat mechanical structure that can serve as a basis for academic programs and a starting point for government, military and commercial large-scale sensing networks, where the cost of each node must be minimized to facilitate system affordability and lower the cost and associated risk of losing any node. Spacecraft Design plays a large role in manufacturability. An intentionally simplified mechanical design is presented which reduces machining costs, as compared to more intricate designs that were considered. Several fabrication approaches are evaluated relative to the low-cost goal.

  8. Review of hardware cost estimation methods, models and tools applied to early phases of space mission planning

    Science.gov (United States)

    Trivailo, O.; Sippel, M.; Şekercioğlu, Y. A.

    2012-08-01

    of an estimate, and techniques and/or methods to attain representative and justifiable cost estimates are consequently discussed. Ultimately, the aim of the paper is to establish a baseline for development of a non-commercial, low cost, transparent cost estimation methodology to be applied during very early program research phases at a complete vehicle system level, for largely unprecedented manned launch vehicles in the future. This paper takes the first step to achieving this through the identification, analysis and understanding of established, existing techniques, models, tools and resources relevant within the space sector.

  9. Using Low-Cost Off-the-Shelf Components for the Development of an On-Orbit CubeSat Centrifuge Laboratory

    Science.gov (United States)

    Lightholder, J.; Polak, A.; Gadau, F.; Thoesen, A.; Thangavelautham, J.; Asphaug, E.

    2015-01-01

    An orbital centrifuge laboratory designed for studying accretion experiments and surface dynamics of asteroids can be a low-cost technology development tool that minimize technology risk associated with landing, surface mobility and manipulation.

  10. Low cost light-sheet microscopy for whole brain imaging

    Science.gov (United States)

    Kumar, Manish; Nasenbeny, Jordan; Kozorovitskiy, Yevgenia

    2018-02-01

    Light-sheet microscopy has evolved as an indispensable tool in imaging biological samples. It can image 3D samples at fast speed, with high-resolution optical sectioning, and with reduced photobleaching effects. These properties make light-sheet microscopy ideal for imaging fluorophores in a variety of biological samples and organisms, e.g. zebrafish, drosophila, cleared mouse brains, etc. While most commercial turnkey light-sheet systems are expensive, the existing lower cost implementations, e.g. OpenSPIM, are focused on achieving high-resolution imaging of small samples or organisms like zebrafish. In this work, we substantially reduce the cost of light-sheet microscope system while targeting to image much larger samples, i.e. cleared mouse brains, at single-cell resolution. The expensive components of a lightsheet system - excitation laser, water-immersion objectives, and translation stage - are replaced with an incoherent laser diode, dry objectives, and a custom-built Arduino-controlled translation stage. A low-cost CUBIC protocol is used to clear fixed mouse brain samples. The open-source platforms of μManager and Fiji support image acquisition, processing, and visualization. Our system can easily be extended to multi-color light-sheet microscopy.

  11. A Web-based cost-effective training tool with possible application to brain injury rehabilitation.

    Science.gov (United States)

    Wang, Peijun; Kreutzer, Ina Anna; Bjärnemo, Robert; Davies, Roy C

    2004-06-01

    Virtual reality (VR) has provoked enormous interest in the medical community. In particular, VR offers therapists new approaches for improving rehabilitation effects. However, most of these VR assistant tools are not very portable, extensible or economical. Due to the vast amount of 3D data, they are not suitable for Internet transfer. Furthermore, in order to run these VR systems smoothly, special hardware devices are needed. As a result, existing VR assistant tools tend to be available in hospitals but not in patients' homes. To overcome these disadvantages, as a case study, this paper proposes a Web-based Virtual Ticket Machine, called WBVTM, using VRML [VRML Consortium, The Virtual Reality Modeling Language: International Standard ISO/IEC DIS 14772-1, 1997, available at ], Java and EAI (External Authoring Interface) [Silicon Graphics, Inc., The External Authoring Interface (EAI), available at ], to help people with acquired brain injury (ABI) to relearn basic living skills at home at a low cost. As these technologies are open standard and feature usability on the Internet, WBVTM achieves the goals of portability, easy accessibility and cost-effectiveness.

  12. A case study using the United Republic of Tanzania: costing nationwide HPV vaccine delivery using the WHO Cervical Cancer Prevention and Control Costing Tool

    Directory of Open Access Journals (Sweden)

    Hutubessy Raymond

    2012-11-01

    Full Text Available Abstract Background The purpose, methods, data sources and assumptions behind the World Health Organization (WHO Cervical Cancer Prevention and Control Costing (C4P tool that was developed to assist low- and middle-income countries (LMICs with planning and costing their nationwide human papillomavirus (HPV vaccination program are presented. Tanzania is presented as a case study where the WHO C4P tool was used to cost and plan the roll-out of HPV vaccines nationwide as part of the national comprehensive cervical cancer prevention and control strategy. Methods The WHO C4P tool focuses on estimating the incremental costs to the health system of vaccinating adolescent girls through school-, health facility- and/or outreach-based strategies. No costs to the user (school girls, parents or caregivers are included. Both financial (or costs to the Ministry of Health and economic costs are estimated. The cost components for service delivery include training, vaccination (health personnel time and transport, stationery for tally sheets and vaccination cards, and so on, social mobilization/IEC (information, education and communication, supervision, and monitoring and evaluation (M&E. The costs of all the resources used for HPV vaccination are totaled and shown with and without the estimated cost of the vaccine. The total cost is also divided by the number of doses administered and number of fully immunized girls (FIGs to estimate the cost per dose and cost per FIG. Results Over five years (2011 to 2015, the cost of establishing an HPV vaccine program that delivers three doses of vaccine to girls at schools via phased national introduction (three regions in year 1, ten regions in year 2 and all 26 regions in years 3 to 5 in Tanzania is estimated to be US$9.2 million (excluding vaccine costs and US$31.5 million (with vaccine assuming a vaccine price of US$5 (GAVI 2011, formerly the Global Alliance for Vaccines and Immunizations. This is equivalent to a

  13. Low Cost Integrated Navigation System for Unmanned Vessel

    Directory of Open Access Journals (Sweden)

    Yang Changsong

    2017-11-01

    Full Text Available Large errors of low-cost MEMS inertial measurement unit (MIMU lead to huge navigation errors, even wrong navigation information. An integrated navigation system for unmanned vessel is proposed. It consists of a low-cost MIMU and Doppler velocity sonar (DVS. This paper presents an integrated navigation method, to improve the performance of navigation system. The integrated navigation system is tested using simulation and semi-physical simulation experiments, whose results show that attitude, velocity and position accuracy has improved awfully, giving exactly accurate navigation results. By means of the combination of low-cost MIMU and DVS, the proposed system is able to overcome fast drift problems of the low cost IMU.

  14. A reliable, compact and low-cost Michelson wavemeter for laser wavelength measurement

    International Nuclear Information System (INIS)

    Fox, P.J.; Scholten, R.E.; Walkiewicz, M.R.; Drullinger, R.E.

    1998-01-01

    We describe the construction and operation of a simple, compact and cost effective Michelson wavemeter with picometer accuracy. The low cost of the device means that it can form the basis of an undergraduate laboratory experiment, yet it is sufficiently reliable and accurate that it has become an important tool in our research laboratory, where it is regularly used to tune lasers to atomic transitions. The usefulness and accuracy of the wavemeter is demonstrated by tuning two separate extended cavity diode lasers to achieve two-step excitation of the Rb 5 2 D state, observed by detecting 420 nm blue fluorescence from the 5 2 D → 6 2 P → 5 2 S decay path. (authors)

  15. Additive Manufacturing of Low Cost Upper Stage Propulsion Components

    Science.gov (United States)

    Protz, Christopher; Bowman, Randy; Cooper, Ken; Fikes, John; Taminger, Karen; Wright, Belinda

    2014-01-01

    NASA is currently developing Additive Manufacturing (AM) technologies and design tools aimed at reducing the costs and manufacturing time of regeneratively cooled rocket engine components. These Low Cost Upper Stage Propulsion (LCUSP) tasks are funded through NASA's Game Changing Development Program in the Space Technology Mission Directorate. The LCUSP project will develop a copper alloy additive manufacturing design process and develop and optimize the Electron Beam Freeform Fabrication (EBF3) manufacturing process to direct deposit a nickel alloy structural jacket and manifolds onto an SLM manufactured GRCop chamber and Ni-alloy nozzle. In order to develop these processes, the project will characterize both the microstructural and mechanical properties of the SLMproduced GRCop-84, and will explore and document novel design techniques specific to AM combustion devices components. These manufacturing technologies will be used to build a 25K-class regenerative chamber and nozzle (to be used with tested DMLS injectors) that will be tested individually and as a system in hot fire tests to demonstrate the applicability of the technologies. These tasks are expected to bring costs and manufacturing time down as spacecraft propulsion systems typically comprise more than 70% of the total vehicle cost and account for a significant portion of the development schedule. Additionally, high pressure/high temperature combustion chambers and nozzles must be regeneratively cooled to survive their operating environment, causing their design to be time consuming and costly to build. LCUSP presents an opportunity to develop and demonstrate a process that can infuse these technologies into industry, build competition, and drive down costs of future engines.

  16. Review of quality assessment tools for family planning programmes in low- and middle-income countries.

    Science.gov (United States)

    Sprockett, Andrea

    2017-03-01

    Measuring and tracking the quality of healthcare is a critical part of improving service delivery, clinic efficiency and health outcomes. However, no standardized or widely accepted tool exists to assess the quality of clinic-based family planning services in low- and middle-income countries. The objective of this literature review was to identify widely used public domain quality assessment tools with existing or potential application in clinic-based family planning programmes. Using PubMed, PopLine, Google Scholar and Google, key terms such as ‘quality assessment tool’, ‘quality assessment method’, ‘quality measurement’, ‘LMIC’, ‘developing country’, ‘family planning’ and ‘reproductive health’ were searched for articles, identifying 20 relevant tools. Tools were assessed to determine the type of quality components assessed, divided into structure and process components, level of application (national or facility), health service domain that can be assessed by the tool, cost and current use of the tool. Tools were also assessed for shortcomings based on application in a low- and middle-income clinic-based family planning programme, including personnel required, re-assessment frequency, assessment of structure, process and outcome quality, comparability of data over time and across facilities and ability to benchmark clinic results to a national benchmark. No tools met all criteria, indicating a critical gap in quality assessment for low- and middle-income family planning programmes. To achieve Universal Health Coverage, agreed on in the Sustainable Development Goals and to improve system-wide healthcare quality, we must develop and widely adopt a standardized quality assessment tool.

  17. Recreational-Grade Sidescan Sonar: Transforming a Low-Cost Leisure Gadget into a High Resolution Riverbed Remote Sensing Tool

    Science.gov (United States)

    Hamill, D. D.; Buscombe, D.; Wheaton, J. M.; Wilcock, P. R.

    2016-12-01

    The size and spatial organization of bed material, bed texture, is a fundamental physical attribute of lotic ecosystems. Traditional methods to map bed texture (such as physical samples and underwater video) are limited by low spatial coverage, and poor precision in positioning. Recreational grade sidescan sonar systems now offer the possibility of imaging submerged riverbed sediments at coverages and resolutions sufficient to identify subtle changes in bed texture, in any navigable body of water, with minimal cost, expertise in sonar, or logistical effort, thereby facilitating the democratization of acoustic imaging of benthic environments, to support ecohydrological studies in shallow water, not subject to the rigors of hydrographic standards, nor the preserve of hydroacoustic expertise and proprietary hydrographic industry software. We investigate the possibility of using recreational grade sidescan sonar for sedimentary change detection using a case study of repeat sidescan imaging of mixed sand-gravel-rock riverbeds in a debris-fan dominated canyon river, at a coverage and resolution that meets the objectives of studies of the effects of changing bed substrates on salmonid spawning. A repeat substrate mapping analysis on data collected between 2012 and 2015 on the Colorado River in Glen, Marble, and Grand Canyons will be presented. A detailed method has been developed to interpret and analyze non-survey-grade sidescan sonar data, encoded within an open source software tool developed by the authors. An automated technique to quantify bed texture directly from sidescan sonar imagery is tested against bed sediment observations from underwater video and multibeam sonar. Predictive relationships between known bed sediment observations and bed texture metrics could provide an objective means to quantify bed textures and to relate changes in bed texture to biological components of an aquatic ecosystem, at high temporal frequency, and with minimal logistical effort

  18. A low cost indoor localization system for mobile robot experimental setup

    Science.gov (United States)

    Adinandra, S.; Syarif, A.

    2018-04-01

    Indoor localization becomes one of the most important part in mobile robot system One fundamental requirement is to provide an easy-to-use and practical localization system for real-time experiments. In this paper we propose a combination of a recent open source virtual reality (VR) tools, a simple MATLAB code and a low cost USB webcam as an indoor mobile robot localization system Using the VR tools as a server and MATLAB as a client, the proposed solution can cover up to 1.6 [m] × 3.2 [m] with the measurement position accuracy up to 1.2 [cm]. The system is insensitive to light, easy to move and can be quickly set up. A series of successful real-time experiments with three different mobile robot types has been conducted.

  19. Open source software and low cost sensors for teaching UAV science

    Science.gov (United States)

    Kefauver, S. C.; Sanchez-Bragado, R.; El-Haddad, G.; Araus, J. L.

    2016-12-01

    Drones, also known as UASs (unmanned aerial systems), UAVs (Unmanned Aerial Vehicles) or RPAS (Remotely piloted aircraft systems), are both useful advanced scientific platforms and recreational toys that are appealing to younger generations. As such, they can make for excellent education tools as well as low-cost scientific research project alternatives. However, the process of taking pretty pictures to remote sensing science can be daunting if one is presented with only expensive software and sensor options. There are a number of open-source tools and low cost platform and sensor options available that can provide excellent scientific research results, and, by often requiring more user-involvement than commercial software and sensors, provide even greater educational benefits. Scale-invariant feature transform (SIFT) algorithm implementations, such as the Microsoft Image Composite Editor (ICE), which can create quality 2D image mosaics with some motion and terrain adjustments and VisualSFM (Structure from Motion), which can provide full image mosaicking with movement and orthorectification capacities. RGB image quantification using alternate color space transforms, such as the BreedPix indices, can be calculated via plugins in the open-source software Fiji (http://fiji.sc/Fiji; http://github.com/george-haddad/CIMMYT). Recent analyses of aerial images from UAVs over different vegetation types and environments have shown RGB metrics can outperform more costly commercial sensors. Specifically, Hue-based pixel counts, the Triangle Greenness Index (TGI), and the Normalized Green Red Difference Index (NGRDI) consistently outperformed NDVI in estimating abiotic and biotic stress impacts on crop health. Also, simple kits are available for NDVI camera conversions. Furthermore, suggestions for multivariate analyses of the different RGB indices in the "R program for statistical computing", such as classification and regression trees can allow for a more approachable

  20. Minim typing--a rapid and low cost MLST based typing tool for Klebsiella pneumoniae.

    Science.gov (United States)

    Andersson, Patiyan; Tong, Steven Y C; Bell, Jan M; Turnidge, John D; Giffard, Philip M

    2012-01-01

    Here we report a single nucleotide polymorphism (SNP) based genotyping method for Klebsiella pneumoniae utilising high-resolution melting (HRM) analysis of fragments within the multilocus sequence typing (MLST) loci. The approach is termed mini-MLST or Minim typing and it has previously been applied to Streptococcus pyogenes, Staphylococcus aureus and Enterococcus faecium. Six SNPs were derived from concatenated MLST sequences on the basis of maximisation of the Simpsons Index of Diversity (D). DNA fragments incorporating these SNPs and predicted to be suitable for HRM analysis were designed. Using the assumption that HRM alleles are defined by G+C content, Minim typing using six fragments was predicted to provide a D = 0.979 against known STs. The method was tested against 202 K. pneumoniae using a blinded approach in which the MLST analyses were performed after the HRM analyses. The HRM-based alleles were indeed in accordance with G+C content, and the Minim typing identified known STs and flagged new STs. The tonB MLST locus was determined to be very diverse, and the two Minim fragments located herein contribute greatly to the resolving power. However these fragments are refractory to amplification in a minority of isolates. Therefore, we assessed the performance of two additional formats: one using only the four fragments located outside the tonB gene (D = 0.929), and the other using HRM data from these four fragments in conjunction with sequencing of the tonB MLST fragment (D = 0.995). The HRM assays were developed on the Rotorgene 6000, and the method was shown to also be robust on the LightCycler 480, allowing a 384-well high through-put format. The assay provides rapid, robust and low-cost typing with fully portable results that can directly be related to current MLST data. Minim typing in combination with molecular screening for antibiotic resistance markers can be a powerful surveillance tool kit.

  1. Minim typing--a rapid and low cost MLST based typing tool for Klebsiella pneumoniae.

    Directory of Open Access Journals (Sweden)

    Patiyan Andersson

    Full Text Available Here we report a single nucleotide polymorphism (SNP based genotyping method for Klebsiella pneumoniae utilising high-resolution melting (HRM analysis of fragments within the multilocus sequence typing (MLST loci. The approach is termed mini-MLST or Minim typing and it has previously been applied to Streptococcus pyogenes, Staphylococcus aureus and Enterococcus faecium. Six SNPs were derived from concatenated MLST sequences on the basis of maximisation of the Simpsons Index of Diversity (D. DNA fragments incorporating these SNPs and predicted to be suitable for HRM analysis were designed. Using the assumption that HRM alleles are defined by G+C content, Minim typing using six fragments was predicted to provide a D = 0.979 against known STs. The method was tested against 202 K. pneumoniae using a blinded approach in which the MLST analyses were performed after the HRM analyses. The HRM-based alleles were indeed in accordance with G+C content, and the Minim typing identified known STs and flagged new STs. The tonB MLST locus was determined to be very diverse, and the two Minim fragments located herein contribute greatly to the resolving power. However these fragments are refractory to amplification in a minority of isolates. Therefore, we assessed the performance of two additional formats: one using only the four fragments located outside the tonB gene (D = 0.929, and the other using HRM data from these four fragments in conjunction with sequencing of the tonB MLST fragment (D = 0.995. The HRM assays were developed on the Rotorgene 6000, and the method was shown to also be robust on the LightCycler 480, allowing a 384-well high through-put format. The assay provides rapid, robust and low-cost typing with fully portable results that can directly be related to current MLST data. Minim typing in combination with molecular screening for antibiotic resistance markers can be a powerful surveillance tool kit.

  2. Survey and Classification of Large Woody Debris (LWD in Streams Using Generated Low-Cost Geomatic Products

    Directory of Open Access Journals (Sweden)

    Damian Ortega-Terol

    2014-11-01

    Full Text Available Water authorities are required to have a survey of large woody debris (LWD in river channels and to manage this aspect of the stream habitat, making decisions on removing, positioning or leaving LWD in a natural state. The main objective of this study is to develop a new methodology that assists in decision making for sustainable management of river channels by using generated low-cost, geomatic products to detect LWD. The use of low-cost photogrammetry based on the use of economical, conventional, non-metric digital cameras mounted on low-cost aircrafts, together with the use of the latest computational vision techniques and open-source geomatic tools, provides useful geomatic products. The proposed methodology, compared with conventional photogrammetry or other traditional methods, led to a cost savings of up to 45%. This work presents several contributions for the area of free and open source software related to Geographic Information System (FOSSGIS applications to LWD management in streams, while developing a QGIS [1] plugin that characterizes the risk from the automatic calculation of geometrical parameters.

  3. Identifying Autism with a Brief and Low-Cost Screening Instrument--OERA: Construct Validity, Invariance Testing, and Agreement between Judges

    Science.gov (United States)

    Paula, Cristiane S.; Cunha, Graccielle Rodrigues; Bordini, Daniela; Brunoni, Decio; Moya, Ana Claudia; Bosa, Cleonice Alves; Mari, Jair J.; Cogo-Moreira, Hugo

    2018-01-01

    Simple and low-cost observational-tools to detect symptoms of Autism Spectrum Disorder (ASD) are still necessary. The OERA is a new assessment tool to screen children eliciting observable behaviors with no substantial knowledge on ASD required. The sample was 99 children aged 3-10: 76 with ASD and 23 without ASD (11/23 had intellectual…

  4. Development of a simple estimation tool for LMFBR construction cost

    International Nuclear Information System (INIS)

    Yoshida, Kazuo; Kinoshita, Izumi

    1999-01-01

    A simple tool for estimating the construction costs of liquid-metal-cooled fast breeder reactors (LMFBRs), 'Simple Cost' was developed in this study. Simple Cost is based on a new estimation formula that can reduce the amount of design data required to estimate construction costs. Consequently, Simple cost can be used to estimate the construction costs of innovative LMFBR concepts for which detailed design has not been carried out. The results of test calculation show that Simple Cost provides cost estimations equivalent to those obtained with conventional methods within the range of plant power from 325 to 1500 MWe. Sensitivity analyses for typical design parameters were conducted using Simple Cost. The effects of four major parameters - reactor vessel diameter, core outlet temperature, sodium handling area and number of secondary loops - on the construction costs of LMFBRs were evaluated quantitatively. The results show that the reduction of sodium handling area is particularly effective in reducing construction costs. (author)

  5. A low-cost colorimeter.

    Science.gov (United States)

    Jones, N B; Riley, C; Sheya, M S; Hosseinmardi, M M

    1984-01-01

    A need for a colorimeter with low capital and maintenance costs has been suggested for countries with foreign exchange problems and no local medical instrumentation industry. This paper puts forward a design for such a device based on a domestic light-bulb, photographic filters and photovoltaic cells. The principle of the design is the use of a balancing technique involving twin light paths for test solution and reference solution and an electronic bridge circuit. It is shown that proper selection of the components will allow the cost objectives to be met and also provide acceptable linearity, precision, accuracy and repeatability.

  6. Assessment of a Low-Cost Ultrasound Pericardiocentesis Model

    Directory of Open Access Journals (Sweden)

    Marco Campo dell'Orto

    2013-01-01

    Full Text Available Introduction. The use of ultrasound during resuscitation is emphasized in the latest European resuscitation council guidelines of 2013 to identify treatable conditions such as pericardial tamponade. The recommended standard treatment of tamponade in various guidelines is pericardiocentesis. As ultrasound guidance lowers the complication rates and increases the patient’s safety, pericardiocentesis should be performed under ultrasound guidance. Acute care physicians actually need to train emergency pericardiocentesis. Methods. We describe in detail a pericardiocentesis ultrasound model, using materials at a cost of about 60 euros. During training courses of focused echocardiography n=67, participants tested the phantom and completed a 16-item questionnaire, assessing the model using a visual analogue scale (VAS. Results. Eleven of fourteen questions were answered with a mean VAS score higher than 60% and thus regarded as showing the strengths of the model. Unrealistically outer appearance and heart shape were rated as weakness of the model. A total mean VAS score of all questions of 63% showed that participants gained confidence for further interventions. Conclusions. Our low-cost pericardiocentesis model, which can be easily constructed, may serve as an effective training tool of ultrasound-guided pericardiocentesis for acute and critical care physicians.

  7. Assessment of a Low-Cost Ultrasound Pericardiocentesis Model

    Science.gov (United States)

    Campo dell'Orto, Marco; Hempel, Dorothea; Starzetz, Agnieszka; Seibel, Armin; Hannemann, Ulf; Walcher, Felix; Breitkreutz, Raoul

    2013-01-01

    Introduction. The use of ultrasound during resuscitation is emphasized in the latest European resuscitation council guidelines of 2013 to identify treatable conditions such as pericardial tamponade. The recommended standard treatment of tamponade in various guidelines is pericardiocentesis. As ultrasound guidance lowers the complication rates and increases the patient's safety, pericardiocentesis should be performed under ultrasound guidance. Acute care physicians actually need to train emergency pericardiocentesis. Methods. We describe in detail a pericardiocentesis ultrasound model, using materials at a cost of about 60 euros. During training courses of focused echocardiography n = 67, participants tested the phantom and completed a 16-item questionnaire, assessing the model using a visual analogue scale (VAS). Results. Eleven of fourteen questions were answered with a mean VAS score higher than 60% and thus regarded as showing the strengths of the model. Unrealistically outer appearance and heart shape were rated as weakness of the model. A total mean VAS score of all questions of 63% showed that participants gained confidence for further interventions. Conclusions. Our low-cost pericardiocentesis model, which can be easily constructed, may serve as an effective training tool of ultrasound-guided pericardiocentesis for acute and critical care physicians. PMID:24288616

  8. Low Cost/Low Noise Variable Pitch Ducted Fan, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — ACI proposes a design for a Propulsor (Low Cost/Low Noise Variable Pitch Ducted Fan) that has wide application in all sectors of Aviation. Propulsor hardware of this...

  9. Low-Cost Servomotor Driver for PFM Control.

    Science.gov (United States)

    Aragon-Jurado, David; Morgado-Estevez, Arturo; Perez-Peña, Fernando

    2017-12-31

    Servomotors have already been around for some decades and they are extremely popular among roboticists due to their simple control technique, reliability and low-cost. They are usually controlled by using Pulse Width Modulation (PWM) and this paper aims to keep the idea of simplicity and low-cost, while introducing a new control technique: Pulse Frequency Modulation (PFM). The objective of this paper is to focus on our development of a low-cost servomotor controller which will allow the research community to use them with PFM. A low-cost commercial servomotor is used as the base system for the development: a small PCB that fits inside the case and allocates all the electronic components to control the motor has been designed to replace the original. The potentiometer is retained as the feedback sensor and a microcontroller is responsible for controlling the position of the motor. The paper compares the performance of a PWM and a PFM controlled servomotor. The comparison shows that the servomotor with our controller achieves a faster mechanism for switching targets and a lower latency. This controller can be used with neuromorphic systems to remove the conversion from events to PWM.

  10. Low profile, low cost, new geometry integrated inductors

    DEFF Research Database (Denmark)

    Ouyang, Ziwei; Thomsen, Ole Cornelius; Andersen, Michael A. E.

    2011-01-01

    windings with well-defined thickness. Many advantages and disadvantages are described in depth. In this work, inverse coupling and direct coupling in the new geometry integrated inductors have been analyzed. Coupling characteristic caused by a special saturation behavior has been emphasis. And also...... variable inductors caused by the special saturation behavior may be utilized in some applications. The new integrated inductors make it possible to build low-profile, low-cost, flexibility DC/DC converters, and it can be extensively designed for the low-voltage and high-current required by the modern...

  11. Kick Detection at the Bit: Early Detection via Low Cost Monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Tost, Brian [National Energy Technology Lab. (NETL), Albany, OR (United States). Oak Ridge Inst. for Science and Education (ORISE); Rose, Kelly [National Energy Technology Lab. (NETL), Albany, OR (United States); Aminzadeh, Fred [Univ. of Southern California, Los Angeles, CA (United States). Dept. of Petroleum Engineering; Ante, Magdalene A. [Univ. of Southern California, Los Angeles, CA (United States). Dept. of Petroleum Engineering; Huerta, Nicolas [National Energy Technology Lab. (NETL), Albany, OR (United States)

    2016-06-07

    Formation fluid influxes (i.e. kicks) pose persistent challenges and operational costs during drilling operations. Implications of kicks range in scale but cumulatively result in substantial costs that affect drilling safety, environment, schedule, and infrastructure. Early kick detection presents a low-cost, easily adopted solution for avoiding well control challenges associated with kicks near the bit. Borehole geophysical tools used during the drilling process as part of the logging-while-drilling (LWD) and measurement-while-drilling (MWD) provide the advantage of offering real-time downhole data. LWD/MWD collect data on both the annulus and borehole wall. The annular data are normally treated as background, and are filtered out to isolate the formation measurements. Because kicks will change the local physical properties of annular fluids, bottom-hole measurements are among the first indicators that a formation fluid has invaded the wellbore. This report describes and validates a technique for using the annular portion of LWD/MWD data to facilitate early kick detection using first order principles. The detection technique leverages data from standard and cost-effective technologies that are typically implemented during well drilling, such as MWD/LWD data in combination with mud-pulse telemetry for data transmission.

  12. Arduino: a low-cost multipurpose lab equipment.

    Science.gov (United States)

    D'Ausilio, Alessandro

    2012-06-01

    Typical experiments in psychological and neurophysiological settings often require the accurate control of multiple input and output signals. These signals are often generated or recorded via computer software and/or external dedicated hardware. Dedicated hardware is usually very expensive and requires additional software to control its behavior. In the present article, I present some accuracy tests on a low-cost and open-source I/O board (Arduino family) that may be useful in many lab environments. One of the strengths of Arduinos is the possibility they afford to load the experimental script on the board's memory and let it run without interfacing with computers or external software, thus granting complete independence, portability, and accuracy. Furthermore, a large community has arisen around the Arduino idea and offers many hardware add-ons and hundreds of free scripts for different projects. Accuracy tests show that Arduino boards may be an inexpensive tool for many psychological and neurophysiological labs.

  13. The high cost of low-acuity ICU outliers.

    Science.gov (United States)

    Dahl, Deborah; Wojtal, Greg G; Breslow, Michael J; Holl, Randy; Huguez, Debra; Stone, David; Korpi, Gloria

    2012-01-01

    Direct variable costs were determined on each hospital day for all patients with an intensive care unit (ICU) stay in four Phoenix-area hospital ICUs. Average daily direct variable cost in the four ICUs ranged from $1,436 to $1,759 and represented 69.4 percent and 45.7 percent of total hospital stay cost for medical and surgical patients, respectively. Daily ICU cost and length of stay (LOS) were higher in patients with higher ICU admission acuity of illness as measured by the APACHE risk prediction methodology; 16.2 percent of patients had an ICU stay in excess of six days, and these LOS outliers accounted for 56.7 percent of total ICU cost. While higher-acuity patients were more likely to be ICU LOS outliers, 11.1 percent of low-risk patients were outliers. The low-risk group included 69.4 percent of the ICU population and accounted for 47 percent of all LOS outliers. Low-risk LOS outliers accounted for 25.3 percent of ICU cost and incurred fivefold higher hospital stay costs and mortality rates. These data suggest that severity of illness is an important determinant of daily resource consumption and LOS, regardless of whether the patient arrives in the ICU with high acuity or develops complications that increase acuity. The finding that a substantial number of long-stay patients come into the ICU with low acuity and deteriorate after ICU admission is not widely recognized and represents an important opportunity to improve patient outcomes and lower costs. ICUs should consider adding low-risk LOS data to their quality and financial performance reports.

  14. Low-cost in vitro fertilization: current insights

    Directory of Open Access Journals (Sweden)

    Teoh PJ

    2014-08-01

    Full Text Available Pek Joo Teoh, Abha MaheshwariAberdeen Fertility Centre, Aberdeen Maternity Hospital, University of Aberdeen, Aberdeen, UKAbstract: Despite the development of in vitro fertilization (IVF more than 30 years ago, the cost of treatment remains high. Furthermore, over the years, more sophisticated technologies and expensive medications have been introduced, making IVF increasingly inaccessible despite the increasing need. Globally, the option to undergo IVF is only available to a privileged few. In recent years, there has been growing interest in exploring strategies to reduce the cost of IVF treatment, which would allow the service to be provided in low-resource settings. In this review, we explore the various ways in which the cost of this treatment can be reduced.Keywords: IVF, low-cost, accessible, developing world

  15. The System Cost Model: A tool for life cycle cost and risk analysis

    International Nuclear Information System (INIS)

    Hsu, K.; Lundeen, A.; Shropshire, D.; Sherick, M.

    1996-01-01

    In May of 1994, Lockheed Idaho Technologies Company (LITCO) in Idaho Falls, Idaho and subcontractors began development of the System Cost Model (SCM) application. The SCM estimates life cycle costs of the entire US Department of Energy (DOE) complex for designing; constructing; operating; and decommissioning treatment, storage, and disposal (TSD) facilities for mixed low-level, low-level, and transuranic waste. The SCM uses parametric cost functions to estimate life cycle costs for various treatment, storage, and disposal modules which reflect planned and existing waste management facilities at DOE installations. In addition, SCM can model new TSD facilities based on capacity needs over the program life cycle. The user can provide input data (default data is included in the SCM) including the volume and nature of waste to be managed, the time period over which the waste is to be managed, and the configuration of the waste management complex (i.e., where each installation's generated waste will be treated, stored, and disposed). Then the SCM uses parametric cost equations to estimate the costs of pre-operations (designing), construction, operations and maintenance, and decommissioning these waste management facilities. The SCM also provides transportation costs for DOE wastes. Transportation costs are provided for truck and rail and include transport of contact-handled, remote-handled, and alpha (transuranic) wastes. A complement to the SCM is the System Cost Model-Risk (SCM-R) model, which provides relative Environmental, Safety, and Health (ES and H) risk information. A relative ES and H risk basis has been developed and applied by LITCO at the INEL. The risk basis is now being automated in the SCM-R to facilitate rapid risk analysis of system alternatives. The added risk functionality will allow combined cost and risk evaluation of EM alternatives

  16. Key issues for low-cost FGD installations

    Energy Technology Data Exchange (ETDEWEB)

    DePriest, W.; Mazurek, J.M. [Sargent & Lundy LLC, Chicago, IL (United States)

    1995-12-01

    This paper will discuss various methods for installing low-cost FGD systems. The paper will include a discussion of various types of FGD systems available, both wet and dry, and will compare the relative cost of each type. Important design issues, such as use of spare equipment, materials of construction, etc. will be presented. An overview of various low-cost construction techniques (i.e., modularization) will be included. This paper will draw heavily from Sargent & Lundy`s database of past and current FGD projects together with information we gathered for several Electric Power Research Institute (EPRI) studies on the subject.

  17. Low-cost automatic activity data recording system

    Directory of Open Access Journals (Sweden)

    Moraes M.F.D.

    1997-01-01

    Full Text Available We describe a low-cost, high quality device capable of monitoring indirect activity by detecting touch-release events on a conducting surface, i.e., the animal's cage cover. In addition to the detecting sensor itself, the system includes an IBM PC interface for prompt data storage. The hardware/software design, while serving for other purposes, is used to record the circadian activity rhythm pattern of rats with time in an automated computerized fashion using minimal cost computer equipment (IBM PC XT. Once the sensor detects a touch-release action of the rat in the upper portion of the cage, the interface sends a command to the PC which records the time (hours-minutes-seconds when the activity occurred. As a result, the computer builds up several files (one per detector/sensor containing a time list of all recorded events. Data can be visualized in terms of actograms, indicating the number of detections per hour, and analyzed by mathematical tools such as Fast Fourier Transform (FFT or cosinor. In order to demonstrate method validation, an experiment was conducted on 8 Wistar rats under 12/12-h light/dark cycle conditions (lights on at 7:00 a.m.. Results show a biological validation of the method since it detected the presence of circadian activity rhythm patterns in the behavior of the rats

  18. Uncertainty in air quality observations using low-cost sensors

    Science.gov (United States)

    Castell, Nuria; Dauge, Franck R.; Dongol, Rozina; Vogt, Matthias; Schneider, Philipp

    2016-04-01

    due to changes in the environmental conditions. Currently there is a lack of testing to ensure adequate sensor performance prior to marketing such instruments. Even when manufacturers provide detailed specification sheets, there is little guarantee that the specifications can actually be met in real-world conditions. Data quality is a pertinent concern, especially when citizens are collecting and interpreting the data by themselves. Poor or unknown data quality can lead to incorrect or inappropriate decisions. We present the experiences gained within the EU project CITI-SENSE, where low-cost sensors are one of the tools employed to empower citizens in air quality issues.

  19. Low cost design of microprocessor EDAC circuit

    International Nuclear Information System (INIS)

    Hao Li; Yu Lixin; Peng Heping; Zhuang Wei

    2015-01-01

    An optimization method of error detection and correction (EDAC) circuit design is proposed. The method involves selecting or constructing EDAC codes of low cost hardware, associated with operation scheduling implementation based on 2-input XOR gates structure, and two actions for reducing hardware cells, which can reduce the delay penalties and area costs of the EDAC circuit effectively. The 32-bit EDAC circuit hardware implementation is selected to make a prototype, based on the 180 nm process. The delay penalties and area costs of the EDAC circuit are evaluated. Results show that the time penalty and area cost of the EDAC circuitries are affected with different parity-check matrices and different hardware implementation for the EDAC codes with the same capability of correction and detection code. This method can be used as a guide for low-cost radiation-hardened microprocessor EDAC circuit design and for more advanced technologies. (paper)

  20. Cost Based Value Stream Mapping as a Sustainable Construction Tool for Underground Pipeline Construction Projects

    Directory of Open Access Journals (Sweden)

    Murat Gunduz

    2017-11-01

    Full Text Available This paper deals with application of Value Stream Mapping (VSM as a sustainable construction tool on a real construction project of installation of underground pipelines. VSM was adapted to reduce the high percentage of non-value-added activities and time wastes during each construction stage and the paper searched for an effective way to consider the cost for studied construction of underground pipeline. This paper is unique in its way that it adopts cost implementation of VSM to improve the productivity in underground pipeline projects. The data was observed and collected from site during construction, indicating the cycle time, value added and non-value added of each construction stage. The current state was built based on these details. This was an eye-opening exercise and a process management tool as a trigger for improvement. After the current state assessment, a future state is attempted by Value Stream Mapping tool balancing the resources using a Line of Balance (LOB technique. Moreover, a sustainable cost estimation model was developed during current state and future state to calculate the cost of underground pipeline construction. The result shows a cost reduction of 20.8% between current and future states. This reflects the importance of the cost based Value Stream Mapping in construction as a sustainable measurement tool. This new tool could be utilized in construction industry to add the sustainability and effective cost management.

  1. Toward a low-cost gait analysis system for clinical and free-living assessment.

    Science.gov (United States)

    Ladha, Cassim; Del Din, Silvia; Nazarpour, Kianoush; Hickey, Aodhan; Morris, Rosie; Catt, Michael; Rochester, Lynn; Godfrey, Alan

    2016-08-01

    Gait is an important clinical assessment tool since changes in gait may reflect changes in general health. Measurement of gait is a complex process which has been restricted to bespoke clinical facilities until recently. The use of inexpensive wearable technologies is an attractive alternative and offers the potential to assess gait in any environment. In this paper we present the development of a low cost analysis gait system built using entirely open source components. The system is used to capture spatio-temporal gait characteristics derived from an existing conceptual model, sensitive to ageing and neurodegenerative pathology (e.g. Parkinson's disease). We demonstrate the system is suitable for use in a clinical unit and will lead to pragmatic use in a free-living (home) environment. The system consists of a wearable (tri-axial accelerometer and gyroscope) with a Raspberry Pi module for data storage and analysis. This forms ongoing work to develop gait as a low cost diagnostic in modern healthcare.

  2. Optimal Vehicle Design Using the Integrated System and Cost Modeling Tool Suite

    Science.gov (United States)

    2010-08-01

    Space Vehicle Costing ( ACEIT ) • New Small Sat Model Development & Production Cost O&M Cost Module  Radiation Exposure  Radiation Detector Response...Reliability OML Availability Risk l l Tools CEA, SRM Model, POST, ACEIT , Inflation Model, Rotor Blade Des, Microsoft Project, ATSV, S/1-iABP...space STK, SOAP – Specific mission • Space Vehicle Design (SMAD) • Space Vehicle Propulsion • Orbit Propagation • Space Vehicle Costing ( ACEIT ) • New

  3. Bioinformatics tools for development of fast and cost effective simple ...

    African Journals Online (AJOL)

    Bioinformatics tools for development of fast and cost effective simple sequence repeat ... comparative mapping and exploration of functional genetic diversity in the ... Already, a number of computer programs have been implemented that aim at ...

  4. A tool for evaluating the potential for cost-effective outcomes measurement

    Directory of Open Access Journals (Sweden)

    Somasekhar MM

    2012-04-01

    Full Text Available Melinda M Somasekhar1, Alfred Bove2, Chris Rausch1, James Degnan3, Cathy T King1, Arnold Meyer11The Albert J Finestone, MD, Office for Continuing Medical Education, 2Section of Cardiology, Temple University School of Medicine, Philadelphia, PA, USA; 3Measurement and Research Center, Temple University, Philadelphia, PA, USAAbstract: Cost related to higher-level outcomes measurement is often very high. However, the cost burden is felt even more by smaller, less well-funded continuing medical education (CME programs. It is possible to overcome financial and participant-related barriers to measuring Level 6 outcomes, which are patient health outcomes. The Temple University School of Medicine’s Office for Continuing Medical Education developed a sequential tool for attaining cost-effective outcomes measurement for determining the likelihood of a CME intervention to produce significant changes in physician performance. The appropriate selection of the CME topic and specific practice change indictors drive this tool. This tool walks providers through a simple YES or NO decision-making list that guides them toward an accurate prediction of potential programmatic outcomes. Factors considered during the decision-making process include whether: (a the intended change(s will have a substantial impact on current practice; (b the intended practice change(s are well supported by clinical data, specialty organization/government recommendations, expert opinion, etc; (c the potential change(s affects a large population; (d external factors, such as system pressures, media pressures, financial pressures, patient pressures, safety pressures, etc, are driving this intended change in performance; (e there is a strong motivation on the part of physicians to implement the intended change(s; and (f the intended change(s is relatively easy to implement within any system of practice. If each of these questions can be responded to positively, there is a higher likelihood

  5. A Low-Cost Computer-Controlled Arduino-Based Educational Laboratory System for Teaching the Fundamentals of Photovoltaic Cells

    Science.gov (United States)

    Zachariadou, K.; Yiasemides, K.; Trougkakos, N.

    2012-01-01

    We present a low-cost, fully computer-controlled, Arduino-based, educational laboratory (SolarInsight) to be used in undergraduate university courses concerned with electrical engineering and physics. The major goal of the system is to provide students with the necessary instrumentation, software tools and methodology in order to learn fundamental…

  6. A Low-Cost Data Acquisition System for Automobile Dynamics Applications.

    Science.gov (United States)

    González, Alejandro; Olazagoitia, José Luis; Vinolas, Jordi

    2018-01-27

    This project addresses the need for the implementation of low-cost acquisition technology in the field of vehicle engineering: the design, development, manufacture, and verification of a low-cost Arduino-based data acquisition platform to be used in <80 Hz data acquisition in vehicle dynamics, using low-cost accelerometers. In addition to this, a comparative study is carried out of professional vibration acquisition technologies and low-cost systems, obtaining optimum results for low- and medium-frequency operations with an error of 2.19% on road tests. It is therefore concluded that these technologies are applicable to the automobile industry, thereby allowing the project costs to be reduced and thus facilitating access to this kind of research that requires limited resources.

  7. ``Low-cost Electronic nose evaluated on Thai-herb of Northern-Thailand samples using multivariate analysis methods''

    Science.gov (United States)

    na ayudhaya, Paisarn Daungjak; Klinbumrung, Arrak; Jaroensutasinee, Krisanadej; Pratontep, Sirapat; Kerdcharoen, Teerakiat

    2009-05-01

    In case of species of natural and aromatic plant originated from the northern Thailand, sensory characteristics, especially odours, have unique identifiers of herbs. The instruments sensory analysis have performed by several of differential of sensing, so call `electronic nose', to be a significantly and rapidly for chemometrics. The signal responses of the low cost electronic nose were evaluated by principal component analysis (PCA). The aims of this paper evaluated various of Thai-herbs grown in Northern of Thailand as data preprocessing tools of the Low-cost electronic nose (enNU-PYO1). The essential oil groups of Thai herbs such as Garlic, Lemongrass, Shallot (potato onion), Onion, Zanthoxylum limonella (Dennst.) Alston (Thai name is Makaen), and Kaffir lime leaf were compared volatilized from selected fresh herbs. Principal component analysis of the original sensor responses did clearly distinguish either all samples. In all cases more than 97% for cross-validated group were classified correctly. The results demonstrated that it was possible to develop in a model to construct a low-cost electronic nose to provide measurement of odoriferous herbs.

  8. A Virtual Tool for Minimum Cost Design of a Wind Turbine Tower with Ring Stiffeners

    Directory of Open Access Journals (Sweden)

    Fatih Karpat

    2013-07-01

    Full Text Available Currently, renewable energy resources are becoming more important to reduce greenhouse gas emissions and increase energy efficiency. Researchers have focused on all components of wind turbines to increase reliability and minimize cost. In this paper, a procedure including a cost analysis method and a particle swarm optimization algorithm has been presented to efficiently design low cost steel wind turbine towers. A virtual tool is developed in MATLAB for the cost optimization of wind turbine steel towers with ring stiffeners using a particle swarm optimization algorithm. A wind turbine tower optimization problem in the literature is solved using the developed computer program. In the optimization procedure the optimization results match very well with the optimization results obtained previously. The wall thickness of the shell segments and the dimensions of the ring stiffeners are selected as the design variables, and the limits of the local buckling for the flat ring stiffeners, the local shell buckling limit, the panel ring buckling limit and the limitation of the frequency are considered the design constraints. Numerical examples are presented to understand the impacts of the design variables on the total cost of the wind turbine tower.

  9. High-Efficient Low-Cost Photovoltaics Recent Developments

    CERN Document Server

    Petrova-Koch, Vesselinka; Goetzberger, Adolf

    2009-01-01

    A bird's-eye view of the development and problems of recent photovoltaic cells and systems and prospects for Si feedstock is presented. High-efficient low-cost PV modules, making use of novel efficient solar cells (based on c-Si or III-V materials), and low cost solar concentrators are in the focus of this book. Recent developments of organic photovoltaics, which is expected to overcome its difficulties and to enter the market soon, are also included.

  10. Minim Typing – A Rapid and Low Cost MLST Based Typing Tool for Klebsiella pneumoniae

    Science.gov (United States)

    Andersson, Patiyan; Tong, Steven Y. C.; Bell, Jan M.; Turnidge, John D.; Giffard, Philip M.

    2012-01-01

    Here we report a single nucleotide polymorphism (SNP) based genotyping method for Klebsiella pneumoniae utilising high-resolution melting (HRM) analysis of fragments within the multilocus sequence typing (MLST) loci. The approach is termed mini-MLST or Minim typing and it has previously been applied to Streptococcus pyogenes, Staphylococcus aureus and Enterococcus faecium. Six SNPs were derived from concatenated MLST sequences on the basis of maximisation of the Simpsons Index of Diversity (D). DNA fragments incorporating these SNPs and predicted to be suitable for HRM analysis were designed. Using the assumption that HRM alleles are defined by G+C content, Minim typing using six fragments was predicted to provide a D = 0.979 against known STs. The method was tested against 202 K. pneumoniae using a blinded approach in which the MLST analyses were performed after the HRM analyses. The HRM-based alleles were indeed in accordance with G+C content, and the Minim typing identified known STs and flagged new STs. The tonB MLST locus was determined to be very diverse, and the two Minim fragments located herein contribute greatly to the resolving power. However these fragments are refractory to amplification in a minority of isolates. Therefore, we assessed the performance of two additional formats: one using only the four fragments located outside the tonB gene (D = 0.929), and the other using HRM data from these four fragments in conjunction with sequencing of the tonB MLST fragment (D = 0.995). The HRM assays were developed on the Rotorgene 6000, and the method was shown to also be robust on the LightCycler 480, allowing a 384-well high through-put format. The assay provides rapid, robust and low-cost typing with fully portable results that can directly be related to current MLST data. Minim typing in combination with molecular screening for antibiotic resistance markers can be a powerful surveillance tool kit. PMID:22428067

  11. COSTMODL - AN AUTOMATED SOFTWARE DEVELOPMENT COST ESTIMATION TOOL

    Science.gov (United States)

    Roush, G. B.

    1994-01-01

    The cost of developing computer software consumes an increasing portion of many organizations' budgets. As this trend continues, the capability to estimate the effort and schedule required to develop a candidate software product becomes increasingly important. COSTMODL is an automated software development estimation tool which fulfills this need. Assimilating COSTMODL to any organization's particular environment can yield significant reduction in the risk of cost overruns and failed projects. This user-customization capability is unmatched by any other available estimation tool. COSTMODL accepts a description of a software product to be developed and computes estimates of the effort required to produce it, the calendar schedule required, and the distribution of effort and staffing as a function of the defined set of development life-cycle phases. This is accomplished by the five cost estimation algorithms incorporated into COSTMODL: the NASA-developed KISS model; the Basic, Intermediate, and Ada COCOMO models; and the Incremental Development model. This choice affords the user the ability to handle project complexities ranging from small, relatively simple projects to very large projects. Unique to COSTMODL is the ability to redefine the life-cycle phases of development and the capability to display a graphic representation of the optimum organizational structure required to develop the subject project, along with required staffing levels and skills. The program is menu-driven and mouse sensitive with an extensive context-sensitive help system that makes it possible for a new user to easily install and operate the program and to learn the fundamentals of cost estimation without having prior training or separate documentation. The implementation of these functions, along with the customization feature, into one program makes COSTMODL unique within the industry. COSTMODL was written for IBM PC compatibles, and it requires Turbo Pascal 5.0 or later and Turbo

  12. Development of hybrid lifecycle cost estimating tool (HLCET) for manufacturing influenced design tradeoff

    Science.gov (United States)

    Sirirojvisuth, Apinut

    In complex aerospace system design, making an effective design decision requires multidisciplinary knowledge from both product and process perspectives. Integrating manufacturing considerations into the design process is most valuable during the early design stages since designers have more freedom to integrate new ideas when changes are relatively inexpensive in terms of time and effort. Several metrics related to manufacturability are cost, time, and manufacturing readiness level (MRL). Yet, there is a lack of structured methodology that quantifies how changes in the design decisions impact these metrics. As a result, a new set of integrated cost analysis tools are proposed in this study to quantify the impacts. Equally important is the capability to integrate this new cost tool into the existing design methodologies without sacrificing agility and flexibility required during the early design phases. To demonstrate the applicability of this concept, a ModelCenter environment is used to develop software architecture that represents Integrated Product and Process Development (IPPD) methodology used in several aerospace systems designs. The environment seamlessly integrates product and process analysis tools and makes effective transition from one design phase to the other while retaining knowledge gained a priori. Then, an advanced cost estimating tool called Hybrid Lifecycle Cost Estimating Tool (HLCET), a hybrid combination of weight-, process-, and activity-based estimating techniques, is integrated with the design framework. A new weight-based lifecycle cost model is created based on Tailored Cost Model (TCM) equations [3]. This lifecycle cost tool estimates the program cost based on vehicle component weights and programmatic assumptions. Additional high fidelity cost tools like process-based and activity-based cost analysis methods can be used to modify the baseline TCM result as more knowledge is accumulated over design iterations. Therefore, with this

  13. Optical incremental rotary encoder in low-cost-design; Optischer inkrementaler Drehgeber in Low-Cost-Bauweise

    Energy Technology Data Exchange (ETDEWEB)

    Hopp, David; Pruss, Christof; Osten, Wolfgang [Stuttgart Univ. (Germany). Inst. fuer Technische Optik; Seybold, Jonathan; Mayer, Volker [Hans-Schickard-Gesellschaft, Stuttgart (DE). Inst. fuer Mikroaufbautechnik (IMAT); Kueck, Heinz [Hans-Schickard-Gesellschaft, Stuttgart (DE). Inst. fuer Mikroaufbautechnik (IMAT); Stuttgart Univ. (Germany). Inst. fuer Zeitmesstechnik, Fein- und Mikrotechnik

    2010-07-01

    We have developed a new concept for low-cost optical encoders to come up to meet the increasing demand for inexpensive rotary sensors. The principal idea is to use a micro patterned plastic disc with metal coating, as it is used for Compact Discs or DVDs. Such encoder discs can be manufactured by an efficient injection compression moulding process. With this well established technique it is possible to achieve highly precise micro patterns while running a cost effective process for high volume production. (orig.)

  14. Evaluation of a low-cost, 3D-printed model for bronchoscopy training.

    Science.gov (United States)

    Parotto, Matteo; Jiansen, Joshua Qua; AboTaiban, Ahmed; Ioukhova, Svetlana; Agzamov, Alisher; Cooper, Richard; O'Leary, Gerald; Meineri, Massimiliano

    2017-01-01

    Flexible bronchoscopy is a fundamental procedure in anaesthesia and critical care medicine. Although learning this procedure is a complex task, the use of simulation-based training provides significant advantages, such as enhanced patient safety. Access to bronchoscopy simulators may be limited in low-resource settings. We have developed a low-cost 3D-printed bronchoscopy training model. A parametric airway model was obtained from an online medical model repository and fabricated using a low-cost 3D printer. The participating physicians had no prior bronchoscopy experience. Participants received a 30-minute lecture on flexible bronchoscopy and were administered a 15-item pre-test questionnaire on bronchoscopy. Afterwards, participants were instructed to perform a series of predetermined bronchoscopy tasks on the 3D printed simulator on 4 consecutive occasions. The time needed to perform the tasks and the quality of task performance (identification of bronchial anatomy, technique, dexterity, lack of trauma) were recorded. Upon completion of the simulator tests, participants were administered the 15-item questionnaire (post-test) once again. Participant satisfaction data on the perceived usefulness and accuracy of the 3D model were collected. A statistical analysis was performed using the t-test. Data are reported as mean values (± standard deviation). The time needed to complete all tasks was 152.9 ± 71.5 sec on the 1st attempt vs. 98.7 ± 40.3 sec on the 4th attempt (P = 0.03). Likewise, the quality of performance score improved from 8.3 ± 6.7 to 18.2 ± 2.5 (P 3D-printed model for bronchoscopy training. This model improved trainee performance and may represent a valid, low-cost bronchoscopy training tool.

  15. Development of low-cost digital subtraction angiography system

    International Nuclear Information System (INIS)

    Ando, Yutaka; Kobayashi, Takeshi; Imai, Yutaka; Yagishita, Akira; Kunieda, Etsuo.

    1983-01-01

    We developed a simple and low-cost DSA system. This system consists of a conventional fluoroscopic equipment for the GI tract and a mini-computer (GAMMA-11) which are connected each other with a video-disc recorder. The uniqueness of our system are 1. low-cost, 2. low-radiation dose, 3. off-line processing, 4. flexibility of software. The analysis of the time-density curve and image processing will bring us a more usefull information than DSA alone. (author)

  16. Design Of A Low Cost Anthropomorphic Robot Hand For Industrial Applications

    Science.gov (United States)

    Allen, P.; Raleigh, B.

    2009-11-01

    Autonomous grasping systems using anthropomorphic robotic end effectors have many applications, and the potential of such devices has inspired researchers to develop many types of grasping systems over the past 30 years. Their research has yielded significant advances in end effector dexterity and functionality. However, due to the cost and complexity associated with such devices, their role has been largely confined to that of being research tools in laboratories. Industry, by contrast, has largely opted for simple, single task, devices. This paper presents a novel low cost anthropomorphic robotic end effector, and in particular the design characteristics that make it more applicable to industrial application. The design brief was (i) to be broadly similar to the human hand in terms of size and performance (ii) be low cost (less than €5000 for the system) and (iii) to provide sufficient performance to allow use in industrial applications. Consisting of three fingers and an opposing thumb, the robotic hand developed has a total of 12 automated degrees of freedom. Another 4 degrees of freedom can be set manually. The specific design of the fingers and thumb, together with the drive arrangement utilizing synchronous belts, yields a simplified kinematics solution for the control of movement. The modular nature of the design is extended also to the palm, which can be easily modified to produce different overall work envelopes for the hand. The drive system and grasping strategies are also detailed.

  17. Cost-effective cloud computing: a case study using the comparative genomics tool, roundup.

    Science.gov (United States)

    Kudtarkar, Parul; Deluca, Todd F; Fusaro, Vincent A; Tonellato, Peter J; Wall, Dennis P

    2010-12-22

    Comparative genomics resources, such as ortholog detection tools and repositories are rapidly increasing in scale and complexity. Cloud computing is an emerging technological paradigm that enables researchers to dynamically build a dedicated virtual cluster and may represent a valuable alternative for large computational tools in bioinformatics. In the present manuscript, we optimize the computation of a large-scale comparative genomics resource-Roundup-using cloud computing, describe the proper operating principles required to achieve computational efficiency on the cloud, and detail important procedures for improving cost-effectiveness to ensure maximal computation at minimal costs. Utilizing the comparative genomics tool, Roundup, as a case study, we computed orthologs among 902 fully sequenced genomes on Amazon's Elastic Compute Cloud. For managing the ortholog processes, we designed a strategy to deploy the web service, Elastic MapReduce, and maximize the use of the cloud while simultaneously minimizing costs. Specifically, we created a model to estimate cloud runtime based on the size and complexity of the genomes being compared that determines in advance the optimal order of the jobs to be submitted. We computed orthologous relationships for 245,323 genome-to-genome comparisons on Amazon's computing cloud, a computation that required just over 200 hours and cost $8,000 USD, at least 40% less than expected under a strategy in which genome comparisons were submitted to the cloud randomly with respect to runtime. Our cost savings projections were based on a model that not only demonstrates the optimal strategy for deploying RSD to the cloud, but also finds the optimal cluster size to minimize waste and maximize usage. Our cost-reduction model is readily adaptable for other comparative genomics tools and potentially of significant benefit to labs seeking to take advantage of the cloud as an alternative to local computing infrastructure.

  18. A precise goniometer/tensiometer using a low cost single-board computer

    Science.gov (United States)

    Favier, Benoit; Chamakos, Nikolaos T.; Papathanasiou, Athanasios G.

    2017-12-01

    Measuring the surface tension and the Young contact angle of a droplet is extremely important for many industrial applications. Here, considering the booming interest for small and cheap but precise experimental instruments, we have constructed a low-cost contact angle goniometer/tensiometer, based on a single-board computer (Raspberry Pi). The device runs an axisymmetric drop shape analysis (ADSA) algorithm written in Python. The code, here named DropToolKit, was developed in-house. We initially present the mathematical framework of our algorithm and then we validate our software tool against other well-established ADSA packages, including the commercial ramé-hart DROPimage Advanced as well as the DropAnalysis plugin in ImageJ. After successfully testing for various combinations of liquids and solid surfaces, we concluded that our prototype device would be highly beneficial for industrial applications as well as for scientific research in wetting phenomena compared to the commercial solutions.

  19. Implementation of a low-cost mobile devices to support medical diagnosis.

    Science.gov (United States)

    García Sánchez, Carlos; Botella Juan, Guillermo; Ayuso Márquez, Fermín; González Rodríguez, Diego; Prieto-Matías, Manuel; Tirado Fernández, Francisco

    2013-01-01

    Medical imaging has become an absolutely essential diagnostic tool for clinical practices; at present, pathologies can be detected with an earliness never before known. Its use has not only been relegated to the field of radiology but also, increasingly, to computer-based imaging processes prior to surgery. Motion analysis, in particular, plays an important role in analyzing activities or behaviors of live objects in medicine. This short paper presents several low-cost hardware implementation approaches for the new generation of tablets and/or smartphones for estimating motion compensation and segmentation in medical images. These systems have been optimized for breast cancer diagnosis using magnetic resonance imaging technology with several advantages over traditional X-ray mammography, for example, obtaining patient information during a short period. This paper also addresses the challenge of offering a medical tool that runs on widespread portable devices, both on tablets and/or smartphones to aid in patient diagnostics.

  20. Implementation of a Low-Cost Mobile Devices to Support Medical Diagnosis

    Directory of Open Access Journals (Sweden)

    Carlos García Sánchez

    2013-01-01

    Full Text Available Medical imaging has become an absolutely essential diagnostic tool for clinical practices; at present, pathologies can be detected with an earliness never before known. Its use has not only been relegated to the field of radiology but also, increasingly, to computer-based imaging processes prior to surgery. Motion analysis, in particular, plays an important role in analyzing activities or behaviors of live objects in medicine. This short paper presents several low-cost hardware implementation approaches for the new generation of tablets and/or smartphones for estimating motion compensation and segmentation in medical images. These systems have been optimized for breast cancer diagnosis using magnetic resonance imaging technology with several advantages over traditional X-ray mammography, for example, obtaining patient information during a short period. This paper also addresses the challenge of offering a medical tool that runs on widespread portable devices, both on tablets and/or smartphones to aid in patient diagnostics.

  1. Transgenic Plants as Low-Cost Platform for Chemotherapeutic Drugs Screening

    Directory of Open Access Journals (Sweden)

    Daniele Vergara

    2015-01-01

    Full Text Available In this work we explored the possibility of using genetically modified Arabidopsis thaliana plants as a rapid and low-cost screening tool for evaluating human anticancer drugs action and efficacy. Here, four different inhibitors with a validated anticancer effect in humans and distinct mechanism of action were screened in the plant model for their ability to interfere with the cytoskeletal and endomembrane networks. We used plants expressing a green fluorescent protein (GFP tagged microtubule-protein (TUA6-GFP, and three soluble GFPs differently sorted to reside in the endoplasmic reticulum (GFPKDEL or to accumulate in the vacuole through a COPII dependent (AleuGFP or independent (GFPChi mechanism. Our results demonstrated that drugs tested alone or in combination differentially influenced the monitored cellular processes including cytoskeletal organization and endomembrane trafficking. In conclusion, we demonstrated that A. thaliana plants are sensitive to the action of human chemotherapeutics and can be used for preliminary screening of drugs efficacy. The cost-effective subcellular imaging in plant cell may contribute to better clarify drugs subcellular targets and their anticancer effects.

  2. Organizing for low cost space operations - Status and plans

    Science.gov (United States)

    Lee, C.

    1976-01-01

    Design features of the Space Transportation System (vehicle reuse, low cost expendable components, simple payload interfaces, standard support systems) must be matched by economical operational methods to achieve low operating and payload costs. Users will be responsible for their own payloads and will be charged according to the services they require. Efficient use of manpower, simple documentation, simplified test, checkout, and flight planning are firm goals, together with flexibility for quick response to varying user needs. Status of the Shuttle hardware, plans for establishing low cost procedures, and the policy for user charges are discussed.

  3. A Proposal for Automatic Fruit Harvesting by Combining a Low Cost Stereovision Camera and a Robotic Arm

    Science.gov (United States)

    Font, Davinia; Pallejà, Tomàs; Tresanchez, Marcel; Runcan, David; Moreno, Javier; Martínez, Dani; Teixidó, Mercè; Palacín, Jordi

    2014-01-01

    This paper proposes the development of an automatic fruit harvesting system by combining a low cost stereovision camera and a robotic arm placed in the gripper tool. The stereovision camera is used to estimate the size, distance and position of the fruits whereas the robotic arm is used to mechanically pickup the fruits. The low cost stereovision system has been tested in laboratory conditions with a reference small object, an apple and a pear at 10 different intermediate distances from the camera. The average distance error was from 4% to 5%, and the average diameter error was up to 30% in the case of a small object and in a range from 2% to 6% in the case of a pear and an apple. The stereovision system has been attached to the gripper tool in order to obtain relative distance, orientation and size of the fruit. The harvesting stage requires the initial fruit location, the computation of the inverse kinematics of the robotic arm in order to place the gripper tool in front of the fruit, and a final pickup approach by iteratively adjusting the vertical and horizontal position of the gripper tool in a closed visual loop. The complete system has been tested in controlled laboratory conditions with uniform illumination applied to the fruits. As a future work, this system will be tested and improved in conventional outdoor farming conditions. PMID:24984059

  4. A Proposal for Automatic Fruit Harvesting by Combining a Low Cost Stereovision Camera and a Robotic Arm

    Directory of Open Access Journals (Sweden)

    Davinia Font

    2014-06-01

    Full Text Available This paper proposes the development of an automatic fruit harvesting system by combining a low cost stereovision camera and a robotic arm placed in the gripper tool. The stereovision camera is used to estimate the size, distance and position of the fruits whereas the robotic arm is used to mechanically pickup the fruits. The low cost stereovision system has been tested in laboratory conditions with a reference small object, an apple and a pear at 10 different intermediate distances from the camera. The average distance error was from 4% to 5%, and the average diameter error was up to 30% in the case of a small object and in a range from 2% to 6% in the case of a pear and an apple. The stereovision system has been attached to the gripper tool in order to obtain relative distance, orientation and size of the fruit. The harvesting stage requires the initial fruit location, the computation of the inverse kinematics of the robotic arm in order to place the gripper tool in front of the fruit, and a final pickup approach by iteratively adjusting the vertical and horizontal position of the gripper tool in a closed visual loop. The complete system has been tested in controlled laboratory conditions with uniform illumination applied to the fruits. As a future work, this system will be tested and improved in conventional outdoor farming conditions.

  5. Low-cost uncooled VOx infrared camera development

    Science.gov (United States)

    Li, Chuan; Han, C. J.; Skidmore, George D.; Cook, Grady; Kubala, Kenny; Bates, Robert; Temple, Dorota; Lannon, John; Hilton, Allan; Glukh, Konstantin; Hardy, Busbee

    2013-06-01

    The DRS Tamarisk® 320 camera, introduced in 2011, is a low cost commercial camera based on the 17 µm pixel pitch 320×240 VOx microbolometer technology. A higher resolution 17 µm pixel pitch 640×480 Tamarisk®640 has also been developed and is now in production serving the commercial markets. Recently, under the DARPA sponsored Low Cost Thermal Imager-Manufacturing (LCTI-M) program and internal project, DRS is leading a team of industrial experts from FiveFocal, RTI International and MEMSCAP to develop a small form factor uncooled infrared camera for the military and commercial markets. The objective of the DARPA LCTI-M program is to develop a low SWaP camera (costs less than US $500 based on a 10,000 units per month production rate. To meet this challenge, DRS is developing several innovative technologies including a small pixel pitch 640×512 VOx uncooled detector, an advanced digital ROIC and low power miniature camera electronics. In addition, DRS and its partners are developing innovative manufacturing processes to reduce production cycle time and costs including wafer scale optic and vacuum packaging manufacturing and a 3-dimensional integrated camera assembly. This paper provides an overview of the DRS Tamarisk® project and LCTI-M related uncooled technology development activities. Highlights of recent progress and challenges will also be discussed. It should be noted that BAE Systems and Raytheon Vision Systems are also participants of the DARPA LCTI-M program.

  6. Process Design and Costing of Bioethanol Technology: A Tool for Determining the Status and Direction of Research and Development.

    Science.gov (United States)

    Wooley; Ruth; Glassner; Sheehan

    1999-10-01

    Bioethanol is a fuel-grade ethanol made from trees, grasses, and waste materials. It represents a sustainable substitute for gasoline in today's passenger cars. Modeling and design of processes for making bioethanol are critical tools used in the U.S. Department of Energy's bioethanol research and development program. We use such analysis to guide new directions for research and to help us understand the level at which and the time when bioethanol will achieve commercial success. This paper provides an update on our latest estimates for current and projected costs of bioethanol. These estimates are the result of very sophisticated modeling and costing efforts undertaken in the program over the past few years. Bioethanol could cost anywhere from $1.16 to $1.44 per gallon, depending on the technology and the availability of low cost feedstocks for conversion to ethanol. While this cost range opens the door to fuel blending opportunities, in which ethanol can be used, for example, to improve the octane rating of gasoline, it is not currently competitive with gasoline as a bulk fuel. Research strategies and goals described in this paper have been translated into cost savings for ethanol. Our analysis of these goals shows that the cost of ethanol could drop by 40 cents per gallon over the next ten years by taking advantage of exciting new tools in biotechnology that will improve yield and performance in the conversion process.

  7. Decision-Making Tool for Cost-Efficient and Environmentally Friendly Wood Mobilisation

    OpenAIRE

    Matevž Triplat; Peter Prislan; Nike Krajnc

    2015-01-01

    Background and Purpose: With development of forest management technologies, the efficiency of wood production was significantly improved, and thus the impact on forests has changed as well. The article presents a practical decision-making tool for selection of most suitable harvesting system, considering given terrain as well as expected soil conditions on harvesting sites. The decision-making tool should support cost-efficient and environmentally friendly mobilisation of wood. Materials a...

  8. Wireless, low-cost, FPGA-based miniature gamma ray spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Becker, E.M., E-mail: beckere@engr.orst.edu; Farsoni, A.T.

    2014-10-11

    A compact, low-cost, wireless gamma-ray spectrometer is a tool sought by a number of different organizations in the field of radiation detection. Such a device has applications in emergency response, battlefield assessment, and personal dosimetry. A prototype device fitting this description has been constructed in the Advanced Radiation Instrumentation Laboratory at Oregon State University. The prototype uses a CsI(Tl) scintillator coupled to a solid-state photomultiplier and a 40 MHz, 12-bit, FPGA-based digital pulse processor to measure gamma radiation, and is able to be accessed wirelessly by mobile phone. The prototype device consumes roughly 420 mW, weighs about 28 g (not including battery), and measures 2.54×3.81 cm{sup 2}. The prototype device is able to achieve 5.9% FWHM energy resolution at 662 keV.

  9. Costs of mixed low-level waste stabilization options

    International Nuclear Information System (INIS)

    Schwinkendorf, W.E.; Cooley, C.R.

    1998-01-01

    Selection of final waste forms to be used for disposal of DOE's mixed low-level waste (MLLW) depends on the waste form characteristics and total life cycle cost. In this paper the various cost factors associated with production and disposal of the final waste form are discussed and combined to develop life-cycle costs associated with several waste stabilization options. Cost factors used in this paper are based on a series of treatment system studies in which cost and mass balance analyses were performed for several mixed low-level waste treatment systems and various waste stabilization methods including vitrification, grout, phosphate bonded ceramic and polymer. Major cost elements include waste form production, final waste form volume, unit disposal cost, and system availability. Production of grout costs less than the production of a vitrified waste form if each treatment process has equal operating time (availability) each year; however, because of the lower volume of a high temperature slag, certification and handling costs and disposal costs of the final waste form are less. Both the total treatment cost and life cycle costs are higher for a system producing grout than for a system producing high temperature slag, assuming equal system availability. The treatment costs decrease with increasing availability regardless of the waste form produced. If the availability of a system producing grout is sufficiently greater than a system producing slag, then the cost of treatment for the grout system will be less than the cost for the slag system, and the life cycle cost (including disposal) may be less depending on the unit disposal cost. Treatment and disposal costs will determine the return on investment in improved system availability

  10. A low cost, adaptive mixed reality system for home-based stroke rehabilitation.

    Science.gov (United States)

    Chen, Yinpeng; Baran, Michael; Sundaram, Hari; Rikakis, Thanassis

    2011-01-01

    This paper presents a novel, low-cost, real-time adaptive multimedia environment for home-based upper extremity rehabilitation of stroke survivors. The primary goal of this system is to provide an interactive tool with which the stroke survivor can sustain gains achieved within the clinical phase of therapy and increase the opportunity for functional recovery. This home-based mediated system has low cost sensing, off the shelf components for the auditory and visual feedback, and remote monitoring capability. The system is designed to continue active learning by reducing dependency on real-time feedback and focusing on summary feedback after a single task and sequences of tasks. To increase system effectiveness through customization, we use data from the training strategy developed by the therapist at the clinic for each stroke survivor to drive automated system adaptation at the home. The adaptation includes changing training focus, selecting proper feedback coupling both in real-time and in summary, and constructing appropriate dialogues with the stroke survivor to promote more efficient use of the system. This system also allows the therapist to review participant's progress and adjust the training strategy weekly.

  11. The SimSpay-Student Perceptions of a Low-Cost Build-It-Yourself Model for Novice Training of Surgical Skills in Canine Ovariohysterectomy

    DEFF Research Database (Denmark)

    Langebæk, Rikke; Toft, Nils; Eriksen, Thomas

    2015-01-01

    -type scale, students were asked to rate their perceived levels of competence, confidence, and anatomic knowledge before and after SimSpay training. Results demonstrate a strongly significant (p perceived levels...... of competence, confidence, and anatomic knowledge, the low-fidelity Sim Spay is a useful, low-cost learning tool for teaching ovariohysterectomy....

  12. A tool for evaluating the potential for cost-effective outcomes measurement.

    Science.gov (United States)

    Somasekhar, Melinda M; Bove, Alfred; Rausch, Chris; Degnan, James; King, Cathy T; Meyer, Arnold

    2012-01-01

    Cost related to higher-level outcomes measurement is often very high. However, the cost burden is felt even more by smaller, less well-funded continuing medical education (CME) programs. It is possible to overcome financial and participant-related barriers to measuring Level 6 outcomes, which are patient health outcomes. The Temple University School of Medicine's Office for Continuing Medical Education developed a sequential tool for attaining cost-effective outcomes measurement for determining the likelihood of a CME intervention to produce significant changes in physician performance. The appropriate selection of the CME topic and specific practice change indictors drive this tool. This tool walks providers through a simple YES or NO decision-making list that guides them toward an accurate prediction of potential programmatic outcomes. Factors considered during the decision-making process include whether: (a) the intended change(s) will have a substantial impact on current practice; (b) the intended practice change(s) are well supported by clinical data, specialty organization/government recommendations, expert opinion, etc; (c) the potential change(s) affects a large population; (d) external factors, such as system pressures, media pressures, financial pressures, patient pressures, safety pressures, etc, are driving this intended change in performance; (e) there is a strong motivation on the part of physicians to implement the intended change(s); and (f) the intended change(s) is relatively easy to implement within any system of practice. If each of these questions can be responded to positively, there is a higher likelihood that the intended practice-related change(s) will occur. Such change can be measured using a simpler and less costly methodology.

  13. Low Cost and Flexible UAV Deployment of Sensors

    DEFF Research Database (Denmark)

    Sørensen, Lars Yndal; Jacobsen, Lars Toft; Hansen, John Paulin

    2017-01-01

    -collection needs. The main contribution is the extensible architecture for modularized airborne sensor deployment and real-time data visualisation. Our open-source Android application provides data collection, flight path definition and map tools. Total cost of the system is below 800 dollars. The flexibility...

  14. PET in tumor imaging: research only or a cost effective clinical tool?

    International Nuclear Information System (INIS)

    Wahl, R.L.

    1997-01-01

    PET imaging has for many years been a versatile tool for non-invasive imaging of neuro-physiology and, indeed, whole body physiology. Quantitative PET imaging of trace amounts of radioactivity is scientifically elegant and can be very complex. This lecture focuses on whether and where this test is clinically useful. Because of the research tradition, PET imaging has been perceived as an 'expensive' test, as it costs more per scan than CT and MRI scans at most institutions. Such a superficial analysis is incorrect, however, as it is increasingly recognized that imaging costs, which in some circumstances will be increased by the use of PET, are only a relatively small component of patient care costs. Thus, PET may raise imaging costs and the number of imaging procedures in some settings, though PET may reduce imaging test numbers in other settings. However, the analysis must focus on the total costs of patient management. Analyses focused on total patient care costs, including cost of hospitalization and cost surgery as well as imaging costs, have shown that PET can substantially reduce total patient care costs in several settings. This is achieved by providing a more accurate diagnosis, and thus having fewer instances of an incorrect diagnosis resulting in subsequent inappropriate surgery or investigations. Several institutions have shown scenarios in which PET for tumor imaging is cost effective. While the specific results of the analyses vary based on disease prevalence and cost input values for each procedure, as well as the projected performance of PET, the similar results showing total care cost savings in the management of several common cancers, strongly supports the rational for the use of PET in cancer management. In addition, promising clinical results are forthcoming in several other illnesses, suggesting PET will have broader utility than these uses, alone. Thus, while PET is an 'expensive' imaging procedure and has considerable utility as a research

  15. Improving Power System Modeling. A Tool to Link Capacity Expansion and Production Cost Models

    Energy Technology Data Exchange (ETDEWEB)

    Diakov, Victor [National Renewable Energy Lab. (NREL), Golden, CO (United States); Cole, Wesley [National Renewable Energy Lab. (NREL), Golden, CO (United States); Sullivan, Patrick [National Renewable Energy Lab. (NREL), Golden, CO (United States); Brinkman, Gregory [National Renewable Energy Lab. (NREL), Golden, CO (United States); Margolis, Robert [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2015-11-01

    Capacity expansion models (CEM) provide a high-level long-term view at the prospects of the evolving power system. In simulating the possibilities of long-term capacity expansion, it is important to maintain the viability of power system operation in the short-term (daily, hourly and sub-hourly) scales. Production-cost models (PCM) simulate routine power system operation on these shorter time scales using detailed load, transmission and generation fleet data by minimizing production costs and following reliability requirements. When based on CEM 'predictions' about generating unit retirements and buildup, PCM provide more detailed simulation for the short-term system operation and, consequently, may confirm the validity of capacity expansion predictions. Further, production cost model simulations of a system that is based on capacity expansion model solution are 'evolutionary' sound: the generator mix is the result of logical sequence of unit retirement and buildup resulting from policy and incentives. The above has motivated us to bridge CEM with PCM by building a capacity expansion - to - production cost model Linking Tool (CEPCoLT). The Linking Tool is built to onset capacity expansion model prescriptions onto production cost model inputs. NREL's ReEDS and Energy Examplar's PLEXOS are the capacity expansion and the production cost models, respectively. Via the Linking Tool, PLEXOS provides details of operation for the regionally-defined ReEDS scenarios.

  16. A low cost, customizable turbidostat for use in synthetic circuit characterization.

    Science.gov (United States)

    Takahashi, Chris N; Miller, Aaron W; Ekness, Felix; Dunham, Maitreya J; Klavins, Eric

    2015-01-16

    Engineered biological circuits are often disturbed by a variety of environmental factors. In batch culture, where the majority of synthetic circuit characterization occurs, environmental conditions vary as the culture matures. Turbidostats are powerful characterization tools that provide static culture environments; however, they are often expensive, especially when purchased in custom configurations, and are difficult to design and construct in a lab. Here, we present a low cost, open source multiplexed turbidostat that can be manufactured and used with minimal experience in electrical or software engineering. We demonstrate the utility of this system to profile synthetic circuit behavior in S. cerevisiae. We also demonstrate the flexibility of the design by showing that a fluorometer can be easily integrated.

  17. AIRQino, a low-cost air quality mobile platform

    Science.gov (United States)

    Zaldei, Alessandro; Vagnoli, Carolina; Di Lonardo, Sara; Gioli, Beniamino; Gualtieri, Giovanni; Toscano, Piero; Martelli, Francesca; Matese, Alessandro

    2015-04-01

    Recent air quality regulations (Directive 2008/50/EC) enforce the transition from point-based monitoring networks to new tools that must be capable of mapping and forecasting air quality on the totality of land area, and therefore the totality of citizens. This implies new technologies such as models and additional indicative measurements, are needed in addition to accurate fixed air quality monitoring stations, that until now have been taken as reference by local administrators for the enforcement of various mitigation strategies. However, due to their sporadic spatial distribution, they cannot describe the highly resolved spatial pollutant variations within cities. Integrating additional indicative measurements may provide adequate information on the spatial distribution of the ambient air quality, also allowing for a reduction of the required minimum number of fixed sampling points, whose high cost and complex maintenance still remain a crucial concern for local administrators. New low-cost and small size sensors are becoming available, that could be employed in air quality monitoring including mobile applications. However, accurate assessment of their accuracy and performance both in controlled and real monitoring conditions is crucially needed. Quantifying sensor response is a significant challenge due to the sensitivity to ambient temperature and humidity and the cross-sensitivity to others pollutant species. This study reports the development of an Arduino compatible electronic board (AIRQino) which integrates a series of low-cost metal oxide and NDIR sensors for air quality monitoring, with sensors to measure air temperature, relative humidity, noise, solar radiation and vertical acceleration. A comparative assessment was made for CO2, CO, NO2, CH4, O3, VOCs concentrations, temperature and relative humidity. A controlled climatic chamber study (-80°C / +80°C) was performed to verify temperature and humidity interference using reference gas cylinders and

  18. Adaptation of the Tool to Estimate Patient Costs Questionnaire into Indonesian Context for Tuberculosis-affected Households

    Directory of Open Access Journals (Sweden)

    Ahmad Fuady

    2018-04-01

    Full Text Available Background: Indonesia is the second-highest country for tuberculosis (TB incidence worldwide. Hence, it urgently requires improvements and innovations beyond the strategies that are currently being implemented throughout the country. One fundamental step in monitoring its progress is by preparing a validated tool to measure total patient costs and catastrophic total costs. The World Health Organization (WHO recommends using a version of the generic questionnaire that has been adapted to the local cultural context in order to interpret findings correctly. This study is aimed to adapt the Tool to Estimate Patient Costs questionnaire into the Indonesian context, which measures total costs and catastrophic total costs for tuberculosis-affected households. Methods: the tool was adapted using best-practice guidelines. On the basis of a pre-test performed in a previous study (referred to as Phase 1 Study, we refined the adaptation process by comparing it with the generic tool introduced by the WHO. We also held an expert committee review and performed pre-testing by interviewing 30 TB patients. After pre-testing, the tool was provided with complete explanation sheets for finalization. Results: seventy-two major changes were made during the adaptation process including changing the answer choices to match the Indonesian context, refining the flow of questions, deleting questions, changing some words and restoring original questions that had been changed in Phase 1 Study. Participants indicated that most questions were clear and easy to understand. To address recall difficulties by the participants, we made some adaptations to obtain data that might be missing, such as tracking data to medical records, developing a proxy of costs and guiding interviewers to ask for a specific value when participants were uncertain about the estimated market value of property they had sold. Conclusion: the adapted Tool to Estimate Patient Costs in Bahasa Indonesia is

  19. Adaptation of the Tool to Estimate Patient Costs Questionnaire into Indonesian Context for Tuberculosis-affected Households.

    Science.gov (United States)

    Fuady, Ahmad; Houweling, Tanja A; Mansyur, Muchtaruddin; Richardus, Jan H

    2018-01-01

    Indonesia is the second-highest country for tuberculosis (TB) incidence worldwide. Hence, it urgently requires improvements and innovations beyond the strategies that are currently being implemented throughout the country. One fundamental step in monitoring its progress is by preparing a validated tool to measure total patient costs and catastrophic total costs. The World Health Organization (WHO) recommends using a version of the generic questionnaire that has been adapted to the local cultural context in order to interpret findings correctly. This study is aimed to adapt the Tool to Estimate Patient Costs questionnaire into the Indonesian context, which measures total costs and catastrophic total costs for tuberculosis-affected households. the tool was adapted using best-practice guidelines. On the basis of a pre-test performed in a previous study (referred to as Phase 1 Study), we refined the adaptation process by comparing it with the generic tool introduced by the WHO. We also held an expert committee review and performed pre-testing by interviewing 30 TB patients. After pre-testing, the tool was provided with complete explanation sheets for finalization. seventy-two major changes were made during the adaptation process including changing the answer choices to match the Indonesian context, refining the flow of questions, deleting questions, changing some words and restoring original questions that had been changed in Phase 1 Study. Participants indicated that most questions were clear and easy to understand. To address recall difficulties by the participants, we made some adaptations to obtain data that might be missing, such as tracking data to medical records, developing a proxy of costs and guiding interviewers to ask for a specific value when participants were uncertain about the estimated market value of property they had sold. the adapted Tool to Estimate Patient Costs in Bahasa Indonesia is comprehensive and ready for use in future studies on TB

  20. Hanford River Protection Project Life cycle Cost Modeling Tool to Enhance Mission Planning - 13396

    International Nuclear Information System (INIS)

    Dunford, Gary; Williams, David; Smith, Rick

    2013-01-01

    The Life cycle Cost Model (LCM) Tool is an overall systems model that incorporates budget, and schedule impacts for the entire life cycle of the River Protection Project (RPP) mission, and is replacing the Hanford Tank Waste Operations Simulator (HTWOS) model as the foundation of the RPP system planning process. Currently, the DOE frequently requests HTWOS simulations of alternative technical and programmatic strategies for completing the RPP mission. Analysis of technical and programmatic changes can be performed with HTWOS; however, life cycle costs and schedules were previously generated by manual transfer of time-based data from HTWOS to Primavera P6. The LCM Tool automates the preparation of life cycle costs and schedules and is needed to provide timely turnaround capability for RPP mission alternative analyses. LCM is the simulation component of the LCM Tool. The simulation component is a replacement of the HTWOS model with new capability to support life cycle cost modeling. It is currently deployed in G22, but has been designed to work in any full object-oriented language with an extensive feature set focused on networking and cross-platform compatibility. The LCM retains existing HTWOS functionality needed to support system planning and alternatives studies going forward. In addition, it incorporates new functionality, coding improvements that streamline programming and model maintenance, and capability to input/export data to/from the LCM using the LCM Database (LCMDB). The LCM Cost/Schedule (LCMCS) contains cost and schedule data and logic. The LCMCS is used to generate life cycle costs and schedules for waste retrieval and processing scenarios. It uses time-based output data from the LCM to produce the logic ties in Primavera P6 necessary for shifting activities. The LCM Tool is evolving to address the needs of decision makers who want to understand the broad spectrum of risks facing complex organizations like DOE-RPP to understand how near

  1. Hanford River Protection Project Life cycle Cost Modeling Tool to Enhance Mission Planning - 13396

    Energy Technology Data Exchange (ETDEWEB)

    Dunford, Gary [AEM Consulting, LLC, 1201 Jadwin Avenue, Richland, WA 99352 (United States); Williams, David [WIT, Inc., 11173 Oak Fern Court, San Diego, CA 92131 (United States); Smith, Rick [Knowledge Systems Design, Inc., 13595 Quaker Hill Cross Rd, Nevada City, CA 95959 (United States)

    2013-07-01

    The Life cycle Cost Model (LCM) Tool is an overall systems model that incorporates budget, and schedule impacts for the entire life cycle of the River Protection Project (RPP) mission, and is replacing the Hanford Tank Waste Operations Simulator (HTWOS) model as the foundation of the RPP system planning process. Currently, the DOE frequently requests HTWOS simulations of alternative technical and programmatic strategies for completing the RPP mission. Analysis of technical and programmatic changes can be performed with HTWOS; however, life cycle costs and schedules were previously generated by manual transfer of time-based data from HTWOS to Primavera P6. The LCM Tool automates the preparation of life cycle costs and schedules and is needed to provide timely turnaround capability for RPP mission alternative analyses. LCM is the simulation component of the LCM Tool. The simulation component is a replacement of the HTWOS model with new capability to support life cycle cost modeling. It is currently deployed in G22, but has been designed to work in any full object-oriented language with an extensive feature set focused on networking and cross-platform compatibility. The LCM retains existing HTWOS functionality needed to support system planning and alternatives studies going forward. In addition, it incorporates new functionality, coding improvements that streamline programming and model maintenance, and capability to input/export data to/from the LCM using the LCM Database (LCMDB). The LCM Cost/Schedule (LCMCS) contains cost and schedule data and logic. The LCMCS is used to generate life cycle costs and schedules for waste retrieval and processing scenarios. It uses time-based output data from the LCM to produce the logic ties in Primavera P6 necessary for shifting activities. The LCM Tool is evolving to address the needs of decision makers who want to understand the broad spectrum of risks facing complex organizations like DOE-RPP to understand how near

  2. Efficacy of Low-Cost PC-Based Aviation Training Devices

    Directory of Open Access Journals (Sweden)

    Savern l Reweti

    2017-03-01

    Full Text Available Aim/Purpose: The aim of this study was to explore whether a full cost flight training device (FTD was significantly better for simulator training than a low cost PC-Based Aviation Training Device (PCATD. Background: A quasi-transfer study was undertaken to ascertain whether a Civil Aviation Authority certified Flight Training Device (FTD was more effective at improving pilot proficiency in the performance of a standard VFR traffic pattern (Overhead Rejoin Procedure than a customised low cost PCATD. Methodology: In this quasi-transfer study, a high fidelity FTD rather than an aircraft was used to test both training and transfer tasks. Ninety-three pilots were recruited to participate in the study. Contribution: The use of PCATDs is now well established for pilot training, especially for Instrument Flight Rules (IFR skills training. However, little substantive research has been undertaken to examine their efficacy for VFR training. Findings: There was no evidence of a pre-test/post-test difference in VFR task perfor-mance between participants trained on the PCATD and the FTD, when post tested on the FTD. The use of both PCATD and FTD demonstrated signifi-cant improvements in VFR task performance compared to a control group that received no PCATD or FTD training. Recommendations for Practitioners\t: We discuss the possibility that low cost PCATDs may be a viable alternative for flight schools wishing to use a flight simulator but not able to afford a FTD. Recommendation for Researchers: We discuss the introduction of improved low cost technologies that allow PCATDs to be used more effectively for training in VFR procedures. The development and testing of new technologies requires more research. Impact on Society: Flight training schools operate in a difficult economic environment with continued increases in the cost of aircraft maintenance, compliance costs, and aviation fuel. The increased utilisation of low cost PCATD’s especially for VFR

  3. State distributed PV policies: Can low cost (to government) policies have a market impact?

    International Nuclear Information System (INIS)

    Krasko, Vitaliy A.; Doris, Elizabeth

    2013-01-01

    This analysis examines the use of state policy as a tool to support the development of distributed generation photovoltaic (PV) markets. The focus is on low-cost market opening policies instead of various forms of government subsidies aimed at reducing installation costs. The ideas tested in this work are: (1) low-cost market opening policies can be effective in facilitating PV market growth without subsidizing projects, and (2) policies can be made more effective if states and localities stage their enactment in a particular order. The policies selected for evaluation emerge from a policy stacking theory outlined in Doris (2012), NREL/CP-7A30-54801, Golden, CO: National Renewable Energy Laboratory. A cross-section econometric analysis that takes into account the quality of interconnection standards, net metering standards, Renewable Portfolio Standards (RPS), RPS set-asides, and a non-policy determinant (population) explains about 70% of the variation in newly installed PV capacity across states and indicates that all of the selected policies are significant. Nonparametric statistical tests confirm the regression results. Qualitative evidence is also presented indicating that effective policy ordering starts with improving interconnection standards, closely followed by improvements in net metering standards, and eventually strengthened by the enactment of an RPS and set-asides. - Highlights: • Impacts of low cost market opening policies on PV capacity are evaluated. • Impact of a strategic policy enactment sequence is evaluated. • Effective interconnection, net metering, RPS, and set-asides increase PV capacity. • Effective ordering is market preparation, then creation, then expansion policies

  4. Quantification of bovine leukemia virus proviral DNA using a low-cost real-time polymerase chain reaction.

    Science.gov (United States)

    Petersen, M I; Alvarez, I; Trono, K G; Jaworski, J P

    2018-04-11

    The detection of bovine leukemia virus (BLV) proviral DNA is an important tool to address whether an animal is infected with BLV. Compared with serological assays, real-time PCR accounts for greater sensitivity and can serve as a confirmatory test for the clarification of inconclusive or discordant serological test results. However, the high cost related to real-time PCR assays has limited their systematic inclusion in BLV surveillance and eradication programs. The aim of the present study was to validate a low-cost quantitative real-time PCR. Interestingly, by using SYBR Green detection dye, we were able to reduce the cost of a single reaction by a factor of 5 compared with most common assays based on the use of fluorogenic probes (i.e., TaqMan technology). This approach allowed a highly sensitive and specific detection and quantification of BLV proviral DNA from purified peripheral blood leukocytes and a milk matrix. Due to its simplicity and low cost, our in-house BLV SYBR quantitative real-time PCR might be used either as a screening or as a confirmatory test in BLV control programs. Copyright © 2018 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  5. Reliability Assessment for Low-cost Unmanned Aerial Vehicles

    Science.gov (United States)

    Freeman, Paul Michael

    Existing low-cost unmanned aerospace systems are unreliable, and engineers must blend reliability analysis with fault-tolerant control in novel ways. This dissertation introduces the University of Minnesota unmanned aerial vehicle flight research platform, a comprehensive simulation and flight test facility for reliability and fault-tolerance research. An industry-standard reliability assessment technique, the failure modes and effects analysis, is performed for an unmanned aircraft. Particular attention is afforded to the control surface and servo-actuation subsystem. Maintaining effector health is essential for safe flight; failures may lead to loss of control incidents. Failure likelihood, severity, and risk are qualitatively assessed for several effector failure modes. Design changes are recommended to improve aircraft reliability based on this analysis. Most notably, the control surfaces are split, providing independent actuation and dual-redundancy. The simulation models for control surface aerodynamic effects are updated to reflect the split surfaces using a first-principles geometric analysis. The failure modes and effects analysis is extended by using a high-fidelity nonlinear aircraft simulation. A trim state discovery is performed to identify the achievable steady, wings-level flight envelope of the healthy and damaged vehicle. Tolerance of elevator actuator failures is studied using familiar tools from linear systems analysis. This analysis reveals significant inherent performance limitations for candidate adaptive/reconfigurable control algorithms used for the vehicle. Moreover, it demonstrates how these tools can be applied in a design feedback loop to make safety-critical unmanned systems more reliable. Control surface impairments that do occur must be quickly and accurately detected. This dissertation also considers fault detection and identification for an unmanned aerial vehicle using model-based and model-free approaches and applies those

  6. Nutritionally Optimized, Culturally Acceptable, Cost-Minimized Diets for Low Income Ghanaian Families Using Linear Programming.

    Science.gov (United States)

    Nykänen, Esa-Pekka A; Dunning, Hanna E; Aryeetey, Richmond N O; Robertson, Aileen; Parlesak, Alexandr

    2018-04-07

    The Ghanaian population suffers from a double burden of malnutrition. Cost of food is considered a barrier to achieving a health-promoting diet. Food prices were collected in major cities and in rural areas in southern Ghana. Linear programming (LP) was used to calculate nutritionally optimized diets (food baskets (FBs)) for a low-income Ghanaian family of four that fulfilled energy and nutrient recommendations in both rural and urban settings. Calculations included implementing cultural acceptability for families living in extreme and moderate poverty (food budget under USD 1.9 and 3.1 per day respectively). Energy-appropriate FBs minimized for cost, following Food Balance Sheets (FBS), lacked key micronutrients such as iodine, vitamin B12 and iron for the mothers. Nutritionally adequate FBs were achieved in all settings when optimizing for a diet cheaper than USD 3.1. However, when delimiting cost to USD 1.9 in rural areas, wild foods had to be included in order to meet nutritional adequacy. Optimization suggested to reduce roots, tubers and fruits and to increase cereals, vegetables and oil-bearing crops compared with FBS. LP is a useful tool to design culturally acceptable diets at minimum cost for low-income Ghanaian families to help advise national authorities how to overcome the double burden of malnutrition.

  7. Low-cost, highly transparent flexible low-e coating film to enable electrochromic windows with increased energy savings

    Energy Technology Data Exchange (ETDEWEB)

    Berland, Brian [ITN Energy Systems, Inc., Littleton, CO (United States); Hollingsworth, Russell [ITN Energy Systems, Inc., Littleton, CO (United States)

    2015-03-31

    Five Quads of energy are lost through windows annually in the U.S. Low-e coatings are increasingly employed to reduce the wasted energy. Most commonly, the low-e coating is an oxide material applied directly to the glass at high temperature. With over 100,000,000 existing homes, a retrofit product is crucial to achieve widespread energy savings. Low-e films, i.e. coatings on polymeric substrates, are now also available to meet this need. However, the traditional oxide materials and process is incompatible with low temperature plastics. Alternate high performing low-e films typically incorporate materials that limit visible transmission to 35% or less. Further, the cost is high. The objective of this award was to develop a retrofit, integrated low-e/electrochromic window film to dramatically reduce energy lost through windows. While field testing of state-of-the-art electrochromic (EC) windows show the energy savings are maximized if a low-e coating is used in conjunction with the EC, available low-e films have a low visible transmission (~70% or less) that limits the achievable clear state and therefore, appearance and energy savings potential. Comprehensive energy savings models were completed at Lawrence Berkeley National Lab (LBNL). A parametric approach was used to project energy usage for windows with a large range of low-e properties across all U.S. climate zones, without limiting the study to materials that had already been produced commercially or made in a lab. The model enables projection of energy savings for low-e films as well as integrated low-e/EC products. This project developed a novel low-e film, optimized for compatibility with EC windows, using low temperature, high deposition rate processes for the growth of low-e coatings on plastic films by microwave plasma enhanced chemical vapor deposition. Silica films with good density and optical properties were demonstrated at deposition rates as high as 130Å/sec. A simple bi-layer low-e stack of

  8. A Low-Cost Data Acquisition System for Automobile Dynamics Applications

    Science.gov (United States)

    González, Alejandro; Vinolas, Jordi

    2018-01-01

    This project addresses the need for the implementation of low-cost acquisition technology in the field of vehicle engineering: the design, development, manufacture, and verification of a low-cost Arduino-based data acquisition platform to be used in project costs to be reduced and thus facilitating access to this kind of research that requires limited resources. PMID:29382039

  9. Cost effectiveness of pediatric pneumococcal conjugate vaccines: a comparative assessment of decision-making tools.

    Science.gov (United States)

    Chaiyakunapruk, Nathorn; Somkrua, Ratchadaporn; Hutubessy, Raymond; Henao, Ana Maria; Hombach, Joachim; Melegaro, Alessia; Edmunds, John W; Beutels, Philippe

    2011-05-12

    Several decision support tools have been developed to aid policymaking regarding the adoption of pneumococcal conjugate vaccine (PCV) into national pediatric immunization programs. The lack of critical appraisal of these tools makes it difficult for decision makers to understand and choose between them. With the aim to guide policymakers on their optimal use, we compared publicly available decision-making tools in relation to their methods, influential parameters and results. The World Health Organization (WHO) requested access to several publicly available cost-effectiveness (CE) tools for PCV from both public and private provenance. All tools were critically assessed according to the WHO's guide for economic evaluations of immunization programs. Key attributes and characteristics were compared and a series of sensitivity analyses was performed to determine the main drivers of the results. The results were compared based on a standardized set of input parameters and assumptions. Three cost-effectiveness modeling tools were provided, including two cohort-based (Pan-American Health Organization (PAHO) ProVac Initiative TriVac, and PneumoADIP) and one population-based model (GlaxoSmithKline's SUPREMES). They all compared the introduction of PCV into national pediatric immunization program with no PCV use. The models were different in terms of model attributes, structure, and data requirement, but captured a similar range of diseases. Herd effects were estimated using different approaches in each model. The main driving parameters were vaccine efficacy against pneumococcal pneumonia, vaccine price, vaccine coverage, serotype coverage and disease burden. With a standardized set of input parameters developed for cohort modeling, TriVac and PneumoADIP produced similar incremental costs and health outcomes, and incremental cost-effectiveness ratios. Vaccine cost (dose price and number of doses), vaccine efficacy and epidemiology of critical endpoint (for example

  10. Low-cost distributed solar-thermal-electric power generation

    Science.gov (United States)

    Der Minassians, Artin; Aschenbach, Konrad H.; Sanders, Seth R.

    2004-01-01

    Due to their high relative cost, solar electric energy systems have yet to be exploited on a widespread basis. It is believed in the energy community that a technology similar to photovoltaic (PV), but offered at about $1/W would lead to widespread deployment at residential and commercial sites. This paper addresses the investigation and feasibility study of a low-cost solar thermal electricity generation technology, suitable for distributed deployment. Specifically, we discuss a system based on nonimaging solar concentrators, integrated with free-piston Stirling engine devices incorporating integrated electric generation. We target concentrator-collector operation at moderate temperatures, in the range of 125°C to 150°C. This temperature is consistent with use of optical concentrators with concentration ratios on the order of 1-2. These low ratio concentrators admit wide angles of radiation acceptance and are thus compatible with no diurnal tracking, and no or only a few seasonal adjustments. Thus, costs and reliability hazards associated with tracking hardware systems are avoided. Further, we note that in the intended application, there is no shortage of incident solar energy, but rather it is the capital cost of the solar-electric system that is most precious. Thus, we outline a strategy for exploiting solar resources in a cost constrained manner. The paper outlines design issues, and a specific design for an appropriately dimensioned free-piston Stirling engine. Only standard low-cost materials and manufacturing methods are required to realize such a machine.

  11. Low-cost solar array structure development

    Science.gov (United States)

    Wilson, A. H.

    1981-06-01

    Early studies of flat-plate arrays have projected costs on the order of $50/square meter for installed array support structures. This report describes an optimized low-cost frame-truss structure that is estimated to cost below $25/square meter, including all markups, shipping an installation. The structure utilizes a planar frame made of members formed from light-gauge galvanized steel sheet and is supposed in the field by treated-wood trusses that are partially buried in trenches. The buried trusses use the overburden soil to carry uplift wind loads and thus to obviate reinforced-concrete foundations. Details of the concept, including design rationale, fabrication and assembly experience, structural testing and fabrication drawings are included.

  12. A Low-Cost, Precision Hydrometer for Classroom Use.

    Science.gov (United States)

    Murphy, Michael D.

    1983-01-01

    Describes a low cost hydrometer which can be assembled by students using stock laboratory items with a total retail cost of 17 cents. Includes list of required materials (with supplies) and experimental results on the instrument's accuracy. (JM)

  13. Low-Cost Precursors to Novel Hydrogen Storage Materials

    International Nuclear Information System (INIS)

    Linehan, Suzanne W.; Chin, Arthur A.; Allen, Nathan T.; Butterick, Robert; Kendall, Nathan T.; Klawiter, I. Leo; Lipiecki, Francis J.; Millar, Dean M.; Molzahn, David C.; November, Samuel J.; Jain, Puja; Nadeau, Sara; Mancroni, Scott

    2010-01-01

    -guided R and D approach, which involved the rapid down-selection of a large number of options (chemical pathways to NaBH 4 ) to a smaller, more manageable number. The research began by conducting an extensive review of the technical and patent literature to identify all possible options. The down-selection was based on evaluation of the options against a set of metrics, and to a large extent occurred before experimentation was initiated. Given the vast amount of literature and patents that has evolved over the years, this approach helped to focus efforts and resources on the options with the highest technical and commercial probability of success. Additionally, a detailed engineering analysis methodology was developed for conducting the cost and energy-efficiency calculations. The methodology utilized a number of inputs and tools (Aspen PEA(trademark), FCHTool, and H2A). The down-selection of chemical pathways to NaBH 4 identified three options that were subsequently pursued experimentally. Metal reduction of borate was investigated in Dow's laboratories, research on electrochemical routes to NaBH 4 was conducted at Pennsylvania State University, and Idaho National Laboratory researchers examined various carbothermal routes for producing NaBH 4 from borate. The electrochemical and carbothermal studies did not yield sufficiently positive results. However, NaBH 4 was produced in high yields and purities by an aluminum-based metal reduction pathway. Solid-solid reactive milling, slurry milling, and solution-phase approaches to metal reduction were investigated, and while both reactive milling and solution-phase routes point to fully recyclable processes, the scale-up of reactive milling processes to produce NaBH 4 is expected to be difficult. Alternatively, a low-cost solution-phase approach to NaBH 4 has been identified that is based on conventional process unit operations and should be amenable to scale-up. Numerous advances in AB synthesis have been made in recent years to

  14. Low-cost safety enhancements for stop-controlled and signalized intersections

    Science.gov (United States)

    2009-05-01

    The purpose of this document is to present information on suggested effective, low-cost intersection countermeasures developed using intersection safety research results and input from an intersection safety expert panel. These low-cost countermeasur...

  15. Testing low cost anaerobic digestion (AD) systems

    Science.gov (United States)

    To evaluate the potential for low technology and low cost digesters for small dairies, BARC and researchers from the University of Maryland installed six modified Taiwanese-model field-scale (FS) digesters near the original dairy manure digester. The FS units receive the same post-separated liquid ...

  16. Technology for low cost solid rocket boosters.

    Science.gov (United States)

    Ciepluch, C.

    1971-01-01

    A review of low cost large solid rocket motors developed at the Lewis Research Center is given. An estimate is made of the total cost reduction obtainable by incorporating this new technology package into the rocket motor design. The propellant, case material, insulation, nozzle ablatives, and thrust vector control are discussed. The effect of the new technology on motor cost is calculated for a typical expandable 260-in. booster application. Included in the cost analysis is the influence of motor performance variations due to specific impulse and weight changes. It is found for this application that motor costs may be reduced by up to 30% and that the economic attractiveness of future large solid rocket motors will be improved when the new technology is implemented.

  17. Design, evaluation, and fabrication of low-cost composite blades for intermediate-size wind turbines

    Science.gov (United States)

    Weingart, O.

    1981-01-01

    Low cost approaches for production of 60 ft long glass fiber/resin composite rotor blades for the MOD-OA wind turbine were identified and evaluated. The most cost-effective configuration was selected for detailed design. Subelement and subscale specimens were fabricated for testing to confirm physical and mechanical properties of the composite blade materials, to develop and evaluate blade fabrication techniques and processes, and to confirm the structural adequacy of the root end joint. Full-scale blade tooling was constructed and a partial blade for tool and process tryout was built. Then two full scale blades were fabricated and delivered to NASA-LeRC for installation on a MOD-OA wind turbine at Clayton, New Mexico for operational testing. Each blade was 60 ft. long with 4.5 ft. chord at root end and 2575 lbs weight including metal hub adapter. The selected blade configuration was a three cell design constructed using a resin impregnated glass fiber tape winding process that allows rapid wrapping of primarily axially oriented fibers onto a tapered mandrel, with tapered wall thickness. The ring winder/transverse filament tape process combination was used for the first time on this program to produce entire rotor blade structures. This approach permitted the complete blade to be wound on stationary mandrels, an improvement which alleviated some of the tooling and process problems encountered on previous composite blade programs.

  18. Activity-Based Costing: A Cost Management Tool.

    Science.gov (United States)

    Turk, Frederick J.

    1993-01-01

    In college and university administration, overhead costs are often charged to programs indiscriminately, whereas the support activities that underlie those costs remain unanalyzed. It is time for institutions to decrease ineffective use of resources. Activity-based management attributes costs more accurately and can improve efficiency. (MSE)

  19. Low Cost Processing of Commingled Thermoplastic Composites

    Science.gov (United States)

    Chiasson, Matthew Lee

    A low cost vacuum consolidation process has been investigated for use with commingled thermoplastic matrix composites. In particular, the vacuum consolidation behaviour of commingled polypropylene/glass fibre and commingled nylon/carbon fibre precursors were studied. Laminates were consolidated in a convection oven under vacuum pressure. During processing, the consolidation of the laminate packs was measured by use of non-contact eddy current sensors. The consolidation curves are then used to tune an empirical consolidation model. The overall quality of the resulting laminates is also discussed. Dynamic mechanical analysis, differential scanning calorimetry and mechanical tensile testing were also performed in order to determine the effects of varying processing parameters on the physical and mechanical properties of the laminates. Through this analysis, it was determined that the nylon/carbon fibre blend was not suitable for vacuum consolidation, while the polypropylene/glass fibre blend is a viable option for vacuum consolidation. The ultimate goal of this work is to provide a foundation from which low cost unmanned aerial vehicle (UAV) components can be designed and manufactured from thermoplastic matrix composites using a low cost processing technique as an alternative to traditional thermoset composite materials.

  20. Multi-photon microscopy with a low-cost and highly efficient Cr:LiCAF laser

    Science.gov (United States)

    Sakadić, Sava; Demirbas, Umit; Mempel, Thorsten R.; Moore, Anna; Ruvinskaya, Svetlana; Boas, David A.; Sennaroglu, Alphan; Kartner, Franz X.; Fujimoto, James G.

    2009-01-01

    Multi-photon microscopy (MPM) is a powerful tool for biomedical imaging, enabling molecular contrast and integrated structural and functional imaging on the cellular and subcellular level. However, the cost and complexity of femtosecond laser sources that are required in MPM are significant hurdles to widespread adoption of this important imaging modality. In this work, we describe femtosecond diode pumped Cr:LiCAF laser technology as a low cost alternative to femtosecond Ti:Sapphire lasers for MPM. Using single mode pump diodes which cost only $150 each, a diode pumped Cr:LiCAF laser generates ~70-fs duration, 1.8-nJ pulses at ~800 nm wavelengths, with a repetition rate of 100 MHz and average output power of 180 mW. Representative examples of MPM imaging in neuroscience, immunology, endocrinology and cancer research using Cr:LiCAF laser technology are presented. These studies demonstrate the potential of this laser source for use in a broad range of MPM applications. PMID:19065223

  1. Artificial intelligent decision support for low-cost launch vehicle integrated mission operations

    Science.gov (United States)

    Szatkowski, Gerard P.; Schultz, Roger

    1988-01-01

    The feasibility, benefits, and risks associated with Artificial Intelligence (AI) Expert Systems applied to low cost space expendable launch vehicle systems are reviewed. This study is in support of the joint USAF/NASA effort to define the next generation of a heavy-lift Advanced Launch System (ALS) which will provide economical and routine access to space. The significant technical goals of the ALS program include: a 10 fold reduction in cost per pound to orbit, launch processing in under 3 weeks, and higher reliability and safety standards than current expendables. Knowledge-based system techniques are being explored for the purpose of automating decision support processes in onboard and ground systems for pre-launch checkout and in-flight operations. Issues such as: satisfying real-time requirements, providing safety validation, hardware and Data Base Management System (DBMS) interfacing, system synergistic effects, human interfaces, and ease of maintainability, have an effect on the viability of expert systems as a useful tool.

  2. Hybrid” airlines – Generating value between low-cost and traditional

    Directory of Open Access Journals (Sweden)

    Stoenescu Cristina

    2017-07-01

    Full Text Available Over the last years, the rise of low-cost airlines has determined significant changes in the airline industry and has shaped the evolution of the existing business models. Low-cost airlines started by offering basic services at very low prices; traditional airlines responded by equally cutting costs and reinventing the services offered, with an orientation towards braking down the fare and implementing add-ons, in order to become cost-efficient. As traditional airlines developed strategies to become competitive in this new environment, low-cost airlines started focusing on new ways of enhancing passenger experience and attracting new market segments. As a result, the fragmentation of the market segments addressed by low cost carriers and traditional airlines became less obvious and the characteristics of both business models started to blend at all levels (airline operation, distribution channels, loyalty programs, fleet selection. Thus, this new competition became the foundation of the development of a new „hybrid” carrier, between the low-cost and the traditional models. This article investigates the characteristics of the newly created business model, both from a theoretical perspective and by analysing several case studies. A particular attention will be granted to the evolution of the Romanian carrier Blue Air towards the “hybrid” model. The article focuses on determining the position of the “hybrid” airline in a market with carriers situated along both sides of this business model: lower cost vs. “better” experience and raises the question on how value can be generated in this context. Another aspect tackled is the understanding of the new segmentation of the market, as a consequence of the development of the new business model. In order to achieve this purpose, a survey has been conducted, aiming to mark out the travel preferences of the passengers travelling through the Henri Coandă International Airport.

  3. Contrast in low-cost operational concepts for orbiting satellites

    Science.gov (United States)

    Walyus, Keith D.; Reis, James; Bradley, Arthur J.

    2002-12-01

    Older spacecraft missions, especially those in low Earth orbit with telemetry intensive requirements, required round-the-clock control center staffing. The state of technology relied on control center personnel to continually examine data, make decisions, resolve anomalies, and file reports. Hubble Space Telescope (HST) is a prime example of this description. Technological advancements in hardware and software over the last decade have yielded increases in productivity and operational efficiency, which result in lower cost. The re-engineering effort of HST, which has recently concluded, utilized emerging technology to reduce cost and increase productivity. New missions, of which NASA's Transition Region and Coronal Explorer Satellite (TRACE) is an example, have benefited from recent technological advancements and are more cost-effective than when HST was first launched. During its launch (1998) and early orbit phase, the TRACE Flight Operations Team (FOT) employed continually staffed operations. Yet once the mission entered its nominal phase, the FOT reduced their staffing to standard weekday business hours. Operations were still conducted at night and during the weekends, but these operations occurred autonomously without compromising their high standards for data collections. For the HST, which launched in 1990, reduced cost operations will employ a different operational concept, when the spacecraft enters its low-cost phase after its final servicing mission in 2004. Primarily due to the spacecraft"s design, the HST Project has determined that single-shift operations will introduce unacceptable risks for the amount of dollars saved. More importantly, significant cost-savings can still be achieved by changing the operational concept for the FOT, while still maintaining round-the-clock staffing. It"s important to note that the low-cost solutions obtained for one satellite may not be applicable for other satellites. This paper will contrast the differences between

  4. Single-Phase Hybrid Switched Reluctance Motor for Low-Power Low-Cost Applications

    DEFF Research Database (Denmark)

    Lu, Kaiyuan; Rasmussen, Peter Omand; Jakobsen, Uffe

    2011-01-01

    This paper presents a new single-phase, Hybrid Switched Reluctance (HSR) motor for low-cost, low-power, pump or fan drive systems. Its single-phase configuration allows use of a simple converter to reduce the system cost. Cheap ferrite magnets are used and arranged in a special flux concentration...... manner to increase effectively the torque density and efficiency of this machine. The efficiency of this machine is comparable to the efficiency of a traditional permanent magnet machine in the similar power range. The cogging torque, due to the existence of the permanent magnetic field, is beneficially...

  5. A complete low cost radon detection system

    International Nuclear Information System (INIS)

    Bayrak, A.; Barlas, E.; Emirhan, E.; Kutlu, Ç.; Ozben, C.S.

    2013-01-01

    Monitoring the 222 Rn activity through the 1200 km long Northern Anatolian fault line, for the purpose of earthquake precursory, requires large number of cost effective radon detectors. We have designed, produced and successfully tested a low cost radon detection system (a radon monitor). In the detector circuit of this monitor, First Sensor PS100-7-CER-2 windowless PIN photodiode and a custom made transempedence/shaping amplifier were used. In order to collect the naturally ionized radon progeny to the surface of the PIN photodiode, a potential of 3500 V was applied between the conductive hemi-spherical shell and the PIN photodiode. In addition to the count rate of the radon progeny, absolute pressure, humidity and temperature were logged during the measurements. A GSM modem was integrated to the system for transferring the measurements from the remote locations to the data process center. - Author-Highlights: • Low cost radon detection. • Integrated GSM modem for early warning of radon anomalies. • Radon detection in environment

  6. Evaluation of a proposal for reliable low-cost grid power with 100% wind, water, and solar.

    Science.gov (United States)

    Clack, Christopher T M; Qvist, Staffan A; Apt, Jay; Bazilian, Morgan; Brandt, Adam R; Caldeira, Ken; Davis, Steven J; Diakov, Victor; Handschy, Mark A; Hines, Paul D H; Jaramillo, Paulina; Kammen, Daniel M; Long, Jane C S; Morgan, M Granger; Reed, Adam; Sivaram, Varun; Sweeney, James; Tynan, George R; Victor, David G; Weyant, John P; Whitacre, Jay F

    2017-06-27

    A number of analyses, meta-analyses, and assessments, including those performed by the Intergovernmental Panel on Climate Change, the National Oceanic and Atmospheric Administration, the National Renewable Energy Laboratory, and the International Energy Agency, have concluded that deployment of a diverse portfolio of clean energy technologies makes a transition to a low-carbon-emission energy system both more feasible and less costly than other pathways. In contrast, Jacobson et al. [Jacobson MZ, Delucchi MA, Cameron MA, Frew BA (2015) Proc Natl Acad Sci USA 112(49):15060-15065] argue that it is feasible to provide "low-cost solutions to the grid reliability problem with 100% penetration of WWS [wind, water and solar power] across all energy sectors in the continental United States between 2050 and 2055", with only electricity and hydrogen as energy carriers. In this paper, we evaluate that study and find significant shortcomings in the analysis. In particular, we point out that this work used invalid modeling tools, contained modeling errors, and made implausible and inadequately supported assumptions. Policy makers should treat with caution any visions of a rapid, reliable, and low-cost transition to entire energy systems that relies almost exclusively on wind, solar, and hydroelectric power.

  7. Cost-effective treatment of low-risk carcinoma not invading bladder muscle.

    Science.gov (United States)

    Green, David A; Rink, Michael; Cha, Eugene K; Xylinas, Evanguelos; Chughtai, Bilal; Scherr, Douglas S; Shariat, Shahrokh F; Lee, Richard K

    2013-03-01

    Study Type - Therapy (cost effectiveness analysis) Level of Evidence 2a What's known on the subject? and What does the study add? Bladder cancer is one of the costliest malignancies to treat throughout the life of a patient. The most cost-effective management for low-risk non-muscle-invasive bladder cancer is not known. The current study shows that employing cystoscopic office fulguration for low-risk appearing bladder cancer recurrences can materially impact the cost-effectiveness of therapy. In a follow-up protocol where office fulguration is routinely employed for low-risk bladder cancers, peri-operative intravesical chemotherapy may not provide any additional cost-effectiveness benefit. To examine the cost-effectiveness of fulguration vs transurethral resection of bladder tumour (TURBT) with and without perioperative intravesical chemotherapy (PIC) for managing low-risk carcinoma not invading bladder muscle (NMIBC). Low-risk NMIBC carries a low progression rate, lending support to the use of office-based fulguration for small recurrences rather than traditional TURBT. A Markov state transition model was created to simulate treatment of NMIBC with vs without PIC, with recurrence treated by formal TURBT vs treatment with fulguration. Costing data were obtained from the Medicare Resource Based Relative Value Scale. Data regarding the success of PIC were obtained from the peer-reviewed literature, as were corresponding utilities for bladder cancer-related procedures. Sensitivity analyses were performed. At 5-year follow-up, a strategy of fulguration without PIC was the most cost-effective (mean cost-effectiveness = US $654.8/quality-adjusted life year), despite a lower recurrence rate with PIC. Both fulguration strategies dominated each TURBT strategy. Sensitivity analysis showed that fulguration without PIC dominated all other strategies when the recurrence rate after PIC was increased to ≥14.2% per year. Similarly, the cost-effectiveness of TURBT becomes more

  8. Retention payoff-based cost per day open regression equations: Application in a user-friendly decision support tool for investment analysis of automated estrus detection technologies.

    Science.gov (United States)

    Dolecheck, K A; Heersche, G; Bewley, J M

    2016-12-01

    Assessing the economic implications of investing in automated estrus detection (AED) technologies can be overwhelming for dairy producers. The objectives of this study were to develop new regression equations for estimating the cost per day open (DO) and to apply the results to create a user-friendly, partial budget, decision support tool for investment analysis of AED technologies. In the resulting decision support tool, the end user can adjust herd-specific inputs regarding general management, current reproductive management strategies, and the proposed AED system. Outputs include expected DO, reproductive cull rate, net present value, and payback period for the proposed AED system. Utility of the decision support tool was demonstrated with an example dairy herd created using data from DairyMetrics (Dairy Records Management Systems, Raleigh, NC), Food and Agricultural Policy Research Institute (Columbia, MO), and published literature. Resulting herd size, rolling herd average milk production, milk price, and feed cost were 323 cows, 10,758kg, $0.41/kg, and $0.20/kg of dry matter, respectively. Automated estrus detection technologies with 2 levels of initial system cost (low: $5,000 vs. high: $10,000), tag price (low: $50 vs. high: $100), and estrus detection rate (low: 60% vs. high: 80%) were compared over a 7-yr investment period. Four scenarios were considered in a demonstration of the investment analysis tool: (1) a herd using 100% visual observation for estrus detection before adopting 100% AED, (2) a herd using 100% visual observation before adopting 75% AED and 25% visual observation, (3) a herd using 100% timed artificial insemination (TAI) before adopting 100% AED, and (4) a herd using 100% TAI before adopting 75% AED and 25% TAI. Net present value in scenarios 1 and 2 was always positive, indicating a positive investment situation. Net present value in scenarios 3 and 4 was always positive in combinations using a $50 tag price, and in scenario 4, the $5

  9. What linear programming contributes: world food programme experience with the "cost of the diet" tool.

    Science.gov (United States)

    Frega, Romeo; Lanfranco, Jose Guerra; De Greve, Sam; Bernardini, Sara; Geniez, Perrine; Grede, Nils; Bloem, Martin; de Pee, Saskia

    2012-09-01

    Linear programming has been used for analyzing children's complementary feeding diets, for optimizing nutrient adequacy of dietary recommendations for a population, and for estimating the economic value of fortified foods. To describe and apply a linear programming tool ("Cost of the Diet") with data from Mozambique to determine what could be cost-effective fortification strategies. Based on locally assessed average household dietary needs, seasonal market prices of available food products, and food composition data, the tool estimates the lowest-cost diet that meets almost all nutrient needs. The results were compared with expenditure data from Mozambique to establish the affordability of this diet by quintiles of the population. Three different applications were illustrated: identifying likely "limiting nutrients," comparing cost effectiveness of different fortification interventions at the household level, and assessing economic access to nutritious foods. The analysis identified iron, vitamin B2, and pantothenic acid as "limiting nutrients." Under the Mozambique conditions, vegetable oil was estimated as a more cost-efficient vehicle for vitamin A fortification than sugar; maize flour may also be an effective vehicle to provide other constraining micronutrients. Multiple micronutrient fortification of maize flour could reduce the cost of the "lowest-cost nutritious diet" by 18%, but even this diet can be afforded by only 20% of the Mozambican population. Within the context of fortification, linear programming can be a useful tool for identifying likely nutrient inadequacies, for comparing fortification options in terms of cost effectiveness, and for illustrating the potential benefit of fortification for improving household access to a nutritious diet.

  10. Preliminary Tests of a New Low-Cost Photogrammetric System

    Science.gov (United States)

    Santise, M.; Thoeni, K.; Roncella, R.; Sloan, S. W.; Giacomini, A.

    2017-11-01

    This paper presents preliminary tests of a new low-cost photogrammetric system for 4D modelling of large scale areas for civil engineering applications. The system consists of five stand-alone units. Each of the units is composed of a Raspberry Pi 2 Model B (RPi2B) single board computer connected to a PiCamera Module V2 (8 MP) and is powered by a 10 W solar panel. The acquisition of the images is performed automatically using Python scripts and the OpenCV library. Images are recorded at different times during the day and automatically uploaded onto a FTP server from where they can be accessed for processing. Preliminary tests and outcomes of the system are discussed in detail. The focus is on the performance assessment of the low-cost sensor and the quality evaluation of the digital surface models generated by the low-cost photogrammetric systems in the field under real test conditions. Two different test cases were set up in order to calibrate the low-cost photogrammetric system and to assess its performance. First comparisons with a TLS model show a good agreement.

  11. PRELIMINARY TESTS OF A NEW LOW-COST PHOTOGRAMMETRIC SYSTEM

    Directory of Open Access Journals (Sweden)

    M. Santise

    2017-11-01

    Full Text Available This paper presents preliminary tests of a new low-cost photogrammetric system for 4D modelling of large scale areas for civil engineering applications. The system consists of five stand-alone units. Each of the units is composed of a Raspberry Pi 2 Model B (RPi2B single board computer connected to a PiCamera Module V2 (8 MP and is powered by a 10 W solar panel. The acquisition of the images is performed automatically using Python scripts and the OpenCV library. Images are recorded at different times during the day and automatically uploaded onto a FTP server from where they can be accessed for processing. Preliminary tests and outcomes of the system are discussed in detail. The focus is on the performance assessment of the low-cost sensor and the quality evaluation of the digital surface models generated by the low-cost photogrammetric systems in the field under real test conditions. Two different test cases were set up in order to calibrate the low-cost photogrammetric system and to assess its performance. First comparisons with a TLS model show a good agreement.

  12. Low cost thermal solar collector

    International Nuclear Information System (INIS)

    Abugderah, M. M.; Schneider, E. L.; Tontini, M. V.

    2006-01-01

    Solar energy is a good alternative in the economy of the electric energy mainly for the water heating. However, the solar heaters used demand a high initial investment, becoming the warm water from solar energy inaccessible to a large part of the society. Thus, a low cost solar heater was developed, constructed and tested in the chemical engineering department of West Parana State University-Unioeste. This equipment consists of 300 cans, divided in 30 columns of 10 cans each, all painted in black to enhance the obsorption of the solar radiation. The columns are connected to a pipe of pvc of 8 liters with 0.085m of external diameter. The equipment is capable to heat 120 liters of water in temperatures around 60 degree centigrade. The heater is insolated in its inferior part with cardboard and aluminum, covered with a transparent plastic in its superior. The system still counts with a insulated thermal reservoir, which can conserve the water in temperatures adjusted for the night non-solar days domestic use. The advantage of the constructed is it low cost material. The results are given an graphical tabular from showing acceptable efficiencies.(Autho

  13. Low cost nuclear data printer

    International Nuclear Information System (INIS)

    Punnachiya, S.; Aungkultewaraksa, S.; Pengphol, S.

    1988-01-01

    The data printer is essential for nuclear radiation measuring system. A low cost nuclear data printer is developed from an electronic printing calculator. It can transfer the counting data from scaler and printout. The basic concept is that the BCD data is transferred and converted to decimal data sequentially by the interfacing circuit. After the counting time is ended, each digit is transferred to the printing calculator by data bus, digit by digit, until all the data are transferred and printed out. The low cost nuclear data printer consists of a CASIO model HR-8 electronic printing calculator and a printer interface model either NT 2602 or NT 2603 which are designed for printing out 6 digit data from the counter/timer CANBERRA model 1772. In this research the NT 2602 interface is designed only to transfer and printing out data. While the NT 2603 interface is designed to transfer, print out and average data. The NT 2603 can average from 2 to 9 sets of counting data. This data interfacing technique can be applied to work with all scientific instruments having readout as digital display and all kinds of electronic printing calculator

  14. Thin film silicon modules: contributions to low cost industrial production

    Energy Technology Data Exchange (ETDEWEB)

    Shah, A. [Universite de Neuchatel, Neuchatel (Switzerland)

    2005-07-01

    This final report for the Swiss Federal Office of Energy (SFOE) discusses the research work done during the two-year period 2003-04 at the Thin-Film Solar Cell Laboratory of the Institute of Microtechnology (IMT) at the University of Neuchatel in Switzerland. The transition from fundamental research work to concrete industrialisation issues, and changes within the research staff are discussed. The main results of the work done are presented, including basic techniques for the production of p-i-n solar cells on glass, new technologies for the deposition of n-i-p cells on low-cost flexible substrates and the optimisation of zinc oxide deposition methods. The key role played by substrate chemistry and roughness in the nucleation and growth of micro-crystalline silicon layers is looked at and diagnostic tools for the analysis of micro-crystalline solar cells are discussed.

  15. LCX: Proposal for a low-cost commercial transport

    Science.gov (United States)

    Hartman, Troy; Hayatdavoudi, Maziar; Hettinga, Joel; Hooper, Matt; Nguyen, Phong

    1994-01-01

    The LCX has been developed in response to a request for proposal for an aircraft with 153 passenger capacity and a range of 3000 nautical miles. The goals of the LCX are to provide an aircraft which will achieve the stated mission requirements at the lowest cost possible, both for the manufacturer and the operator. Low cost in this request is defined as short and long term profitability. To achieve this objective, modern technologies attributing to low-cost operation without greatly increasing the cost of manufacturing were employed. These technologies include hybrid laminar flow control and the use of developing new manufacturing processes and philosophies. The LCX will provide a competitive alternative to the use of the Airbus A319/320/321 and the Boeing 737 series of aircraft. The LCX has a maximum weight of 150,000 lb. carried by a wing of 1140 ft(exp 2) and an aspect ratio of 10. The selling price of the LCX is 31 million in 1994 US dollars.

  16. Low cost open data acquisition system for biomedical applications

    Science.gov (United States)

    Zabolotny, Wojciech M.; Laniewski-Wollk, Przemyslaw; Zaworski, Wojciech

    2005-09-01

    In the biomedical applications it is often necessary to collect measurement data from different devices. It is relatively easy, if the devices are equipped with a MIB or Ethernet interface, however often they feature only the asynchronous serial link, and sometimes the measured values are available only as the analog signals. The system presented in the paper is a low cost alternative to commercially available data acquisition systems. The hardware and software architecture of the system is fully open, so it is possible to customize it for particular needs. The presented system offers various possibilities to connect it to the computer based data processing unit - e.g. using the USB or Ethernet ports. Both interfaces allow also to use many such systems in parallel to increase amount of serial and analog inputs. The open source software used in the system makes possible to process the acquired data with standard tools like MATLAB, Scilab or Octave, or with a dedicated, user supplied application.

  17. Design Tools for Cost-Effective Implementation of Planetary Protection Requirements

    Science.gov (United States)

    Hamlin, Louise; Belz, Andrea; Evans, Michael; Kastner, Jason; Satter, Celeste; Spry, Andy

    2006-01-01

    Since the Viking missions to Mars in the 1970s, accounting for the costs associated with planetary protection implementation has not been done systematically during early project formulation phases, leading to unanticipated costs during subsequent implementation phases of flight projects. The simultaneous development of more stringent planetary protection requirements, resulting from new knowledge about the limits of life on Earth, together with current plans to conduct life-detection experiments on a number of different solar system target bodies motivates a systematic approach to integrating planetary protection requirements and mission design. A current development effort at NASA's Jet Propulsion Laboratory is aimed at integrating planetary protection requirements more fully into the early phases of mission architecture formulation and at developing tools to more rigorously predict associated cost and schedule impacts of architecture options chosen to meet planetary protection requirements.

  18. High-precision and low-cost vibration generator for low-frequency calibration system

    Science.gov (United States)

    Li, Rui-Jun; Lei, Ying-Jun; Zhang, Lian-Sheng; Chang, Zhen-Xin; Fan, Kuang-Chao; Cheng, Zhen-Ying; Hu, Peng-Hao

    2018-03-01

    Low-frequency vibration is one of the harmful factors that affect the accuracy of micro-/nano-measuring machines because its amplitude is significantly small and it is very difficult to avoid. In this paper, a low-cost and high-precision vibration generator was developed to calibrate an optical accelerometer, which is self-designed to detect low-frequency vibration. A piezoelectric actuator is used as vibration exciter, a leaf spring made of beryllium copper is used as an elastic component, and a high-resolution, low-thermal-drift eddy current sensor is applied to investigate the vibrator’s performance. Experimental results demonstrate that the vibration generator can achieve steady output displacement with frequency range from 0.6 Hz to 50 Hz, an analytical displacement resolution of 3.1 nm and an acceleration range from 3.72 mm s-2 to 1935.41 mm s-2 with a relative standard deviation less than 1.79%. The effectiveness of the high-precision and low-cost vibration generator was verified by calibrating our optical accelerometer.

  19. Low-cost in vitro fertilization: current insights

    Science.gov (United States)

    Teoh, Pek Joo; Maheshwari, Abha

    2014-01-01

    Despite the development of in vitro fertilization (IVF) more than 30 years ago, the cost of treatment remains high. Furthermore, over the years, more sophisticated technologies and expensive medications have been introduced, making IVF increasingly inaccessible despite the increasing need. Globally, the option to undergo IVF is only available to a privileged few. In recent years, there has been growing interest in exploring strategies to reduce the cost of IVF treatment, which would allow the service to be provided in low-resource settings. In this review, we explore the various ways in which the cost of this treatment can be reduced. PMID:25187741

  20. THE MARKETING MIX FOR LOW COST HEALTHCARE

    OpenAIRE

    Julie George; Dr. Manita D. Shah

    2017-01-01

    The Indian health care industry has a history of dealing with poor doctor-patient ratio, shortage of medical professionals, poor health infrastructure, and low expenditure on healthcare information technology; steep out of pocket spending (OOP), low health insurance coverage, inadequate government spending, poor access to health care facilities and social stigma related to diseases. The unique mindset and ability for frugality has successfully been applied in offering low cost healthcare of u...

  1. Low-cost encapsulation materials for terrestrial solar cell modules

    Science.gov (United States)

    Cuddihy, E. F.; Baum, B.; Willis, P.

    1979-01-01

    The paper presents the findings of material surveys intended to identify low cost materials which could be functional as encapsulants (by 1986) for terrestrial solar cell modules. Economic analyses have indicated that in order to meet the low cost goal of $2.70 per sq m, some or all of the following material technologies must be developed or advanced: (1) UV screening outer covers; (2) elastomeric acrylics; (3) weatherproofing and waterproofing of structural wood and paper products; (4) transparent UV stabilizers for the UV-sensitive transparent pottants; and (5) cost-effective utilization of silicone and fluorocarbon materials.

  2. Cost Effective Recovery of Low-TDS Frac Flowback Water for Re-use

    Energy Technology Data Exchange (ETDEWEB)

    Claire Henderson; Harish Acharya; Hope Matis; Hareesh Kommepalli; Brian Moore; Hua Wang

    2011-03-31

    disposal costs and regulations, a parametric value assessment tool was created to assess the economic attractiveness of a given flowback recovery process relative to conventional disposal for any combination of anticipated flowback TDS and local disposal cost. It is concluded that membrane systems in combination with appropriate pretreatment technologies can provide cost-effective recovery of low-TDS flow-back water for either beneficial reuse or safe surface discharge.

  3. DryCardTM — A Low-Cost Dryness Indicator for Dried Products

    Directory of Open Access Journals (Sweden)

    James F. Thompson

    2017-10-01

    Full Text Available Mycotoxin contamination of food and feed is a significant health hazard in humid areas of the world. Fungal development can be halted if the water activity of dried products is kept below 0.65. This preliminary study evaluates the color response and response time of a low-cost humidity indicator that estimates water activity. The DryCardTM has a consistent color response to relative humidity and its response time is fast enough to be used in practical situations for estimating water activity. The card comes with use instructions and it can be reused many times. It is a crucial tool to assist smallholder farmers and traders in ensuring their crops have been adequately dried.

  4. Guideposts for Low Carbon Finance

    International Nuclear Information System (INIS)

    Pizer, Billy

    2015-01-01

    The author proposes four guideposts for efficient low carbon finance: remove subsidies for high-carbon technologies, improve the cost-effectiveness of low-carbon subsidies, encourage private sector innovation and maintain transparent public policy tools that support cost-benefit accounting

  5. Investment opportunity : the FPL low-cost solar dry kiln

    Science.gov (United States)

    George B. Harpole

    1988-01-01

    Two equations are presented that may be used to estimate a maximum investment limit and working capital requirements for the FPL low-cost solar dry kiln systems. The equations require data for drying cycle time, green lumber cost, and kiln-dried lumber costs. Results are intended to provide a preliminary estimate.

  6. Ignoring the sacroiliac joint in chronic low back pain is costly

    Directory of Open Access Journals (Sweden)

    Polly DW

    2016-01-01

    Full Text Available David W Polly,1,2 Daniel Cher3 1Department of Orthopedic Surgery, 2Department of Neurosurgery, University of Minnesota, Minneapolis, MN, 3SI-BONE, Inc., San Jose, CA, USA Background: Increasing evidence supports minimally invasive sacroiliac joint (SIJ fusion as a safe and effective treatment for SIJ dysfunction. Failure to include the SIJ in the diagnostic evaluation of low back pain could result in unnecessary health care expenses. Design: Decision analytic cost model. Methods: A decision analytic model calculating 2-year direct health care costs in patients with chronic low back pain considering lumbar fusion surgery was used. Results: The strategy of including the SIJ in the preoperative diagnostic workup of chronic low back pain saves an expected US$3,100 per patient over 2 years. Cost savings were robust to reasonable ranges for costs and probabilities, such as the probability of diagnosis and the probability of successful surgical treatment. Conclusion: Including the SIJ as part of the diagnostic strategy in preoperative patients with chronic low back pain is likely to be cost saving in the short term. Keywords: chronic low back pain, lumbar fusion, sacroiliac joint pain, sacroiliac joint fusion, healthcare costs, decision modeling

  7. Observing Fluorescent Probes in Living Cells using a Low-Cost LED Flashlight Retrofitted to a Common Vintage Light Microscope

    Directory of Open Access Journals (Sweden)

    G. A. Babbitt

    2013-03-01

    Full Text Available While the application of molecular biological techniques based upon fluorescent probes has rapidly expanded over recent decades, the equipment cost of fluorescent microscopy has largely prevented its adoption in the college and high school classroom. We offer a simple solution to this problem by describing in detail how to build with simple tools, a fluorescent microscope using a common brand of colored LED flashlights and second-hand components of vintage Nikon microscopes. This extremely low cost solution is qualitatively compared to an expensive modern Zeiss system.

  8. A Study of the dimensional accuracy obtained by low cost 3D printing for possible application in medicine

    Science.gov (United States)

    Kitsakis, K.; Alabey, P.; Kechagias, J.; Vaxevanidis, N.

    2016-11-01

    Low cost 3D printing' is a terminology that referred to the fused filament fabrication (FFF) technique, which constructs physical prototypes, by depositing material layer by layer using a thermal nozzle head. Nowadays, 3D printing is widely used in medical applications such as tissue engineering as well as supporting tool in diagnosis and treatment in Neurosurgery, Orthopedic and Dental-Cranio-Maxillo-Facial surgery. 3D CAD medical models are usually obtained by MRI or CT scans and then are sent to a 3D printer for physical model creation. The present paper is focused on a brief overview of benefits and limitations of 3D printing applications in the field of medicine as well as on a dimensional accuracy study of low-cost 3D printing technique.

  9. Design of low cost glaucoma screening

    NARCIS (Netherlands)

    Niessen, A. G.; Langerhorst, C. T.; Geijssen, H. C.; Greve, E. L.

    1997-01-01

    In 1991 the Netherlands Glaucoma Patient Association organized a glaucoma screening survey. This survey was designed to evaluate the effectiveness of a low cost screening setting. During a screening period of 8 days, 1259 subjects over the age of 49 years were examined by a team of

  10. Calculating Optimum sowing factor: A tool to evaluate sowing strategies and minimize seedling production cost

    Science.gov (United States)

    Eric van Steenis

    2013-01-01

    This paper illustrates how to use an excel spreadsheet as a decision-making tool to determine optimum sowing factor to minimize seedling production cost. Factors incorporated into the spreadsheet calculations include germination percentage, seeder accuracy, cost per seed, cavities per block, costs of handling, thinning, and transplanting labor, and more. In addition to...

  11. Low-Cost IoT: A Holistic Approach

    Directory of Open Access Journals (Sweden)

    Augusto Ciuffoletti

    2018-05-01

    Full Text Available The key factors for a successful smart-city project are its initial cost and its scalability. The initial cost depends on several inter-related aspects that cannot be designed and optimized separately. After the pilot deployment, scaling-up takes place only if the cost remains affordable: an initial financial support may induce dependencies from technologies that become unsustainable in the long period. In addition, the initial adoption of an emerging technology that fails to affirm may jeopardize investment return. This paper investigates a smart-village use case, the success of which strongly depends on the initial cost and scalability, exploring a low-cost way for Internet of Things (IoT. We propose a simple conceptual framework for cost evaluation, and we verify its effectiveness with an exhaustive use case: a prototype sensor designed and tested with its surrounding eco-system. Using experimental results, we can estimate both performance and cost for a pilot system made of fifty sensors deployed in an urban area. We show that such cost grows linearly with system size, taking advantage of widely adopted technologies. The code and the design of the prototype are available, so that all steps are reproducible.

  12. Low-Cost Precursors to Novel Hydrogen Storage Materials

    Energy Technology Data Exchange (ETDEWEB)

    Suzanne W. Linehan; Arthur A. Chin; Nathan T. Allen; Robert Butterick; Nathan T. Kendall; I. Leo Klawiter; Francis J. Lipiecki; Dean M. Millar; David C. Molzahn; Samuel J. November; Puja Jain; Sara Nadeau; Scott Mancroni

    2010-12-31

    project utilized an engineering-guided R&D approach, which involved the rapid down-selection of a large number of options (chemical pathways to NaBH{sub 4}) to a smaller, more manageable number. The research began by conducting an extensive review of the technical and patent literature to identify all possible options. The down-selection was based on evaluation of the options against a set of metrics, and to a large extent occurred before experimentation was initiated. Given the vast amount of literature and patents that has evolved over the years, this approach helped to focus efforts and resources on the options with the highest technical and commercial probability of success. Additionally, a detailed engineering analysis methodology was developed for conducting the cost and energy-efficiency calculations. The methodology utilized a number of inputs and tools (Aspen PEA{trademark}, FCHTool, and H2A). The down-selection of chemical pathways to NaBH{sub 4} identified three options that were subsequently pursued experimentally. Metal reduction of borate was investigated in Dow's laboratories, research on electrochemical routes to NaBH{sub 4} was conducted at Pennsylvania State University, and Idaho National Laboratory researchers examined various carbothermal routes for producing NaBH{sub 4} from borate. The electrochemical and carbothermal studies did not yield sufficiently positive results. However, NaBH{sub 4} was produced in high yields and purities by an aluminum-based metal reduction pathway. Solid-solid reactive milling, slurry milling, and solution-phase approaches to metal reduction were investigated, and while both reactive milling and solution-phase routes point to fully recyclable processes, the scale-up of reactive milling processes to produce NaBH{sub 4} is expected to be difficult. Alternatively, a low-cost solution-phase approach to NaBH{sub 4} has been identified that is based on conventional process unit operations and should be amenable to scale

  13. Teaching basic life support: a prospective randomized study on low-cost training strategies in secondary schools.

    Science.gov (United States)

    Van Raemdonck, Veerle; Monsieurs, Koenraad G; Aerenhouts, Dirk; De Martelaer, Kristine

    2014-08-01

    Cardiopulmonary resuscitation (CPR) training at school is recommended. Limited school resources prevent implementation. The learning efficacy of low-cost training strategies is unknown. To evaluate the efficacy of different CPR learning strategies using low-cost didactic tools. Children (n=593, 15-16 years) were randomized to four training conditions: (1) manikin+teacher instruction (control group), (2) manikin+video instruction, (3) foam dice+plastic bag+peer training+teacher instruction, and (4) foam dice+plastic bag+peer training+video instruction. After a 50 min training, a 3 min CPR test on a manikin was performed using SkillReporting Software (Laerdal, Norway), and repeated after 6 months. The data of children without previous CPR training were analysed. Analysis of variance and the χ-test assessed differences between groups. Complete data sets were available for 165 pupils. Initially, group 3 scored lower on the mean ventilation volume (Pbasics of CPR can be taught with alternative equipment if manikins are not available.

  14. Directions of organisational and low-cost energy saving of engineering enterprises

    Directory of Open Access Journals (Sweden)

    Dzhedzhula Viacheslav V.

    2014-01-01

    Full Text Available The article analyses directions of energy saving of industrial enterprises. Taking into account the tendency to continuous growth of cost of energy resources, introduction of measures that would allow reduction of energy consumption of enterprises is an urgent task. One of the most important obstacles in the process of introduction of energy efficient solutions are fund limits and low awareness of owners and managers of industrial enterprises. The article offers a new classification of energy saving measures: apart from traditional expense and organisation measures it introduces the low-cost measures notion. It offers to consider low-cost those measures that are realised by the enterprise by means of own funds, moreover, their repayment term is not more than one year. It offers analytical expression for identification of annual funds saving from introduction of low-cost measures. It considers the process of identification of saving of funds from introduction of some of the main low-cost measures in detail: replacement of lighting units, balancing of ventilation networks and elimination of water leakages from pipelines and water supply equipment. Based on the analysis of bibliography information the article provides a list of main measures on energy saving, which could be referred to the low-cost ones. The proposed approaches would allow paying more attention to practical aspects of realisation of the concept of energy saving in the industry.

  15. Validity and reliability of a low-cost digital dynamometer for measuring isometric strength of lower limb.

    Science.gov (United States)

    Romero-Franco, Natalia; Jiménez-Reyes, Pedro; Montaño-Munuera, Juan A

    2017-11-01

    Lower limb isometric strength is a key parameter to monitor the training process or recognise muscle weakness and injury risk. However, valid and reliable methods to evaluate it often require high-cost tools. The aim of this study was to analyse the concurrent validity and reliability of a low-cost digital dynamometer for measuring isometric strength in lower limb. Eleven physically active and healthy participants performed maximal isometric strength for: flexion and extension of ankle, flexion and extension of knee, flexion, extension, adduction, abduction, internal and external rotation of hip. Data obtained by the digital dynamometer were compared with the isokinetic dynamometer to examine its concurrent validity. Data obtained by the digital dynamometer from 2 different evaluators and 2 different sessions were compared to examine its inter-rater and intra-rater reliability. Intra-class correlation (ICC) for validity was excellent in every movement (ICC > 0.9). Intra and inter-tester reliability was excellent for all the movements assessed (ICC > 0.75). The low-cost digital dynamometer demonstrated strong concurrent validity and excellent intra and inter-tester reliability for assessing isometric strength in the main lower limb movements.

  16. Heap: a highly sensitive and accurate SNP detection tool for low-coverage high-throughput sequencing data

    KAUST Repository

    Kobayashi, Masaaki

    2017-04-20

    Recent availability of large-scale genomic resources enables us to conduct so called genome-wide association studies (GWAS) and genomic prediction (GP) studies, particularly with next-generation sequencing (NGS) data. The effectiveness of GWAS and GP depends on not only their mathematical models, but the quality and quantity of variants employed in the analysis. In NGS single nucleotide polymorphism (SNP) calling, conventional tools ideally require more reads for higher SNP sensitivity and accuracy. In this study, we aimed to develop a tool, Heap, that enables robustly sensitive and accurate calling of SNPs, particularly with a low coverage NGS data, which must be aligned to the reference genome sequences in advance. To reduce false positive SNPs, Heap determines genotypes and calls SNPs at each site except for sites at the both ends of reads or containing a minor allele supported by only one read. Performance comparison with existing tools showed that Heap achieved the highest F-scores with low coverage (7X) restriction-site associated DNA sequencing reads of sorghum and rice individuals. This will facilitate cost-effective GWAS and GP studies in this NGS era. Code and documentation of Heap are freely available from https://github.com/meiji-bioinf/heap (29 March 2017, date last accessed) and our web site (http://bioinf.mind.meiji.ac.jp/lab/en/tools.html (29 March 2017, date last accessed)).

  17. Low cost submarine robot

    Directory of Open Access Journals (Sweden)

    Ponlachart Chotikarn

    2010-10-01

    Full Text Available A submarine robot is a semi-autonomous submarine robot used mainly for marine environmental research. We aim todevelop a low cost, semi-autonomous submarine robot which is able to travel underwater. The robot’s structure was designedand patented using a novel idea of the diving system employing a volume adjustment mechanism to vary the robot’s density.A light weight, flexibility and small structure provided by PVC can be used to construct the torpedo-liked shape robot.Hydraulic seal and O-ring rubbers are used to prevent water leaking. This robot is controlled by a wired communicationsystem.

  18. Usability of Low-Cost Android Data Collection System for Community-Based Participatory Research.

    Science.gov (United States)

    Salihu, Hamisu M; Salinas-Miranda, Abraham; Turner, DeAnne; King, Lindsey; Paothong, Arnut; Austin, Deborah; Berry, Estrellita Lo

    2016-01-01

    Android tablet computers can be valuable tools for data collection, but their usability has not been evaluated in community-based participatory research (CBPR). This article examines the usability of a low-cost bilingual touchscreen computerized survey system using Android tablets, piloted with a sample of 201 community residents in Tampa, Florida, from November 2013 to March 2014. Needs assessment questions were designed with the droidSURVEY software, and deployed using Android tablet computers. In addition, participants were asked questions about system usability. The mean system usability was 77.57 ± 17.66 (range, 0-100). The mean completion time for taking the 63 survey questions in the needs assessment was 23.11 ± 9.62 minutes. The survey completion rate was optimal (100%), with only 6.34% missingness per variable. We found no sociodemographic differences in usability scores. Our findings indicate that Android tablets could serve as useful tools in CBPR studies.

  19. Low Cost, High-Throughput 3-D Pulmonary Imager Using Hyperpolarized Contrast Agents and Low-Field MRI

    Science.gov (United States)

    2017-10-01

    greater gas polarizations and production amounts/ throughputs- benefiting in particular from the advent of com- pact, high-power, relatively low- cost ...Award Number: W81XWH-15-1-0271 TITLE: Low- Cost , High-Throughput 3-D Pulmonary Imager Using Hyperpolarized Contrast Agents and Low-Field MRI...DISTRIBUTION STATEMENT: Approved for Public Release; Distribution Unlimited The views, opinions and/or findings contained in this report are those of the

  20. Fast and low-cost method for VBES bathymetry generation in coastal areas

    Science.gov (United States)

    Sánchez-Carnero, N.; Aceña, S.; Rodríguez-Pérez, D.; Couñago, E.; Fraile, P.; Freire, J.

    2012-12-01

    Sea floor topography is key information in coastal area management. Nowadays, LiDAR and multibeam technologies provide accurate bathymetries in those areas; however these methodologies are yet too expensive for small customers (fishermen associations, small research groups) willing to keep a periodic surveillance of environmental resources. In this paper, we analyse a simple methodology for vertical beam echosounder (VBES) bathymetric data acquisition and postprocessing, using low-cost means and free customizable tools such as ECOSONS and gvSIG (that is compared with industry standard ArcGIS). Echosounder data was filtered, resampled and, interpolated (using kriging or radial basis functions). Moreover, the presented methodology includes two data correction processes: Monte Carlo simulation, used to reduce GPS errors, and manually applied bathymetric line transformations, both improving the obtained results. As an example, we present the bathymetry of the Ría de Cedeira (Galicia, NW Spain), a good testbed area for coastal bathymetry methodologies given its extension and rich topography. The statistical analysis, performed by direct ground-truthing, rendered an upper bound of 1.7 m error, at 95% confidence level, and 0.7 m r.m.s. (cross-validation provided 30 cm and 25 cm, respectively). The methodology presented is fast and easy to implement, accurate outside transects (accuracy can be estimated), and can be used as a low-cost periodical monitoring method.

  1. Sliver Solar Cells: High-Efficiency, Low-Cost PV Technology

    Directory of Open Access Journals (Sweden)

    Evan Franklin

    2007-01-01

    Full Text Available Sliver cells are thin, single-crystal silicon solar cells fabricated using standard fabrication technology. Sliver modules, composed of several thousand individual Sliver cells, can be efficient, low-cost, bifacial, transparent, flexible, shadow tolerant, and lightweight. Compared with current PV technology, mature Sliver technology will need 10% of the pure silicon and fewer than 5% of the wafer starts per MW of factory output. This paper deals with two distinct challenges related to Sliver cell and Sliver module production: providing a mature and robust Sliver cell fabrication method which produces a high yield of highly efficient Sliver cells, and which is suitable for transfer to industry; and, handling, electrically interconnecting, and encapsulating billions of sliver cells at low cost. Sliver cells with efficiencies of 20% have been fabricated at ANU using a reliable, optimised processing sequence, while low-cost encapsulation methods have been demonstrated using a submodule technique.

  2. Alternative affinity tools: more attractive than antibodies?

    NARCIS (Netherlands)

    Ruigrok, V.J.B.; Levisson, M.; Eppink, M.H.M.; Smidt, H.; Oost, van der J.

    2011-01-01

    Antibodies are the most successful affinity tools used today, in both fundamental and applied research (diagnostics, purification and therapeutics). Nonetheless, antibodies do have their limitations, including high production costs and low stability. Alternative affinity tools based on nucleic acids

  3. Web-based Tool Identifies and Quantifies Potential Cost Savings Measures at the Hanford Site

    International Nuclear Information System (INIS)

    Renevitz, Marisa J.; Peschong, Jon C.; Charboneau, Briant L.; Simpson, Brett C.

    2014-01-01

    The Technical Improvement system is an approachable web-based tool that is available to Hanford DOE staff, site contractors, and general support service contractors as part of the baseline optimization effort underway at the Hanford Site. Finding and implementing technical improvements are a large part of DOE's cost savings efforts. The Technical Improvement dashboard is a key tool for brainstorming and monitoring the progress of submitted baseline optimization and potential cost/schedule efficiencies. The dashboard is accessible to users over the Hanford Local Area Network (HLAN) and provides a highly visual and straightforward status to management on the ideas provided, alleviating the need for resource intensive weekly and monthly reviews

  4. Automated packaging platform for low-cost high-performance optical components manufacturing

    Science.gov (United States)

    Ku, Robert T.

    2004-05-01

    Delivering high performance integrated optical components at low cost is critical to the continuing recovery and growth of the optical communications industry. In today's market, network equipment vendors need to provide their customers with new solutions that reduce operating expenses and enable new revenue generating IP services. They must depend on the availability of highly integrated optical modules exhibiting high performance, small package size, low power consumption, and most importantly, low cost. The cost of typical optical system hardware is dominated by linecards that are in turn cost-dominated by transmitters and receivers or transceivers and transponders. Cost effective packaging of optical components in these small size modules is becoming the biggest challenge to be addressed. For many traditional component suppliers in our industry, the combination of small size, high performance, and low cost appears to be in conflict and not feasible with conventional product design concepts and labor intensive manual assembly and test. With the advent of photonic integration, there are a variety of materials, optics, substrates, active/passive devices, and mechanical/RF piece parts to manage in manufacturing to achieve high performance at low cost. The use of automation has been demonstrated to surpass manual operation in cost (even with very low labor cost) as well as product uniformity and quality. In this paper, we will discuss the value of using an automated packaging platform.for the assembly and test of high performance active components, such as 2.5Gb/s and 10 Gb/s sources and receivers. Low cost, high performance manufacturing can best be achieved by leveraging a flexible packaging platform to address a multitude of laser and detector devices, integration of electronics and handle various package bodies and fiber configurations. This paper describes the operation and results of working robotic assemblers in the manufacture of a Laser Optical Subassembly

  5. Low Cost Vision Based Personal Mobile Mapping System

    Science.gov (United States)

    Amami, M. M.; Smith, M. J.; Kokkas, N.

    2014-03-01

    Mobile mapping systems (MMS) can be used for several purposes, such as transportation, highway infrastructure mapping and GIS data collecting. However, the acceptance of these systems is not wide spread and their use is still limited due the high cost and dependency on the Global Navigation Satellite System (GNSS). A low cost vision based personal MMS has been produced with an aim to overcome these limitations. The system has been designed to depend mainly on cameras and use of low cost GNSS and inertial sensors to provide a bundle adjustment solution with initial values. The system has the potential to be used indoor and outdoor. The system has been tested indoors and outdoors with different GPS coverage, surrounded features, and narrow and curvy paths. Tests show that the system is able to work in such environments providing 3D coordinates of better than 10 cm accuracy.

  6. Low Cost Vision Based Personal Mobile Mapping System

    Directory of Open Access Journals (Sweden)

    M. M. Amami

    2014-03-01

    Full Text Available Mobile mapping systems (MMS can be used for several purposes, such as transportation, highway infrastructure mapping and GIS data collecting. However, the acceptance of these systems is not wide spread and their use is still limited due the high cost and dependency on the Global Navigation Satellite System (GNSS. A low cost vision based personal MMS has been produced with an aim to overcome these limitations. The system has been designed to depend mainly on cameras and use of low cost GNSS and inertial sensors to provide a bundle adjustment solution with initial values. The system has the potential to be used indoor and outdoor. The system has been tested indoors and outdoors with different GPS coverage, surrounded features, and narrow and curvy paths. Tests show that the system is able to work in such environments providing 3D coordinates of better than 10 cm accuracy.

  7. Low-Cost, High-Throughput 3-D Pulmonary Imager Using Hyperpolarized Contrast Agents and Low-Field MRI

    Science.gov (United States)

    2017-10-01

    low- cost and high-throughput was a key element proposed for this project, which we believe will be of significant benefit to the patients suffering...Award Number: W81XWH-15-1-0272 TITLE: Low- Cost , High-Throughput 3-D Pulmonary Imager Using Hyperpolarized Contrast Agents and Low-Field MRI...STATEMENT: Approved for Public Release; Distribution Unlimited The views, opinions and/or findings contained in this report are those of the author(s

  8. Cost effective interventions for the prevention of cardiovascular disease in low and middle income countries: a systematic review.

    Science.gov (United States)

    Shroufi, Amir; Chowdhury, Rajiv; Anchala, Raghupathy; Stevens, Sarah; Blanco, Patricia; Han, Tha; Niessen, Louis; Franco, Oscar H

    2013-03-28

    While there is good evidence to show that behavioural and lifestyle interventions can reduce cardiovascular disease risk factors in affluent settings, less evidence exists in lower income settings.This study systematically assesses the evidence on cost-effectiveness for preventive cardiovascular interventions in low and middle-income settings. Systematic review of economic evaluations on interventions for prevention of cardiovascular disease. PubMed, Web of Knowledge, Scopus and Embase, Opensigle, the Cochrane database, Business Source Complete, the NHS Economic Evaluations Database, reference lists and email contact with experts. we included economic evaluations conducted in adults, reporting the effect of interventions to prevent cardiovascular disease in low and middle income countries as defined by the World Bank. The primary outcome was a change in cardiovascular disease occurrence including coronary heart disease, heart failure and stroke. After selection of the studies, data were extracted by two independent investigators using a previously constructed tool and quality was evaluated using Drummond's quality assessment score. From 9731 search results we found 16 studies, which presented economic outcomes for interventions to prevent cardiovascular disease in low and middle income settings, with most of these reporting positive cost effectiveness results.When the same interventions were evaluated across settings, within and between papers, the likelihood of an intervention being judged cost effective was generally lower in regions with lowest gross national income. While population based interventions were in most cases more cost effective, cost effectiveness estimates for individual pharmacological interventions were overall based upon a stronger evidence base. While more studies of cardiovascular preventive interventions are needed in low and mid income settings, the available high-level of evidence supports a wide range of interventions for the prevention

  9. Designing a Low-Cost Multifunctional Infant Incubator.

    Science.gov (United States)

    Tran, Kevin; Gibson, Aaron; Wong, Don; Tilahun, Dagmawi; Selock, Nicholas; Good, Theresa; Ram, Geetha; Tolosa, Leah; Tolosa, Michael; Kostov, Yordan; Woo, Hyung Chul; Frizzell, Michael; Fulda, Victor; Gopinath, Ramya; Prasad, J Shashidhara; Sudarshan, Hanumappa; Venkatesan, Arunkumar; Kumar, V Sashi; Shylaja, N; Rao, Govind

    2014-06-01

    Every year, an unacceptably large number of infant deaths occur in developing nations, with premature birth and asphyxia being two of the leading causes. A well-regulated thermal environment is critical for neonatal survival. Advanced incubators currently exist, but they are far too expensive to meet the needs of developing nations. We are developing a thermodynamically advanced low-cost incubator suitable for operation in a low-resource environment. Our design features three innovations: (1) a disposable baby chamber to reduce infant mortality due to nosocomial infections, (2) a passive cooling mechanism using low-cost heat pipes and evaporative cooling from locally found clay pots, and (3) insulated panels and a thermal bank consisting of water that effectively preserve and store heat. We developed a prototype incubator and visited and presented our design to our partnership hospital site in Mysore, India. After obtaining feedback, we have determined realistic, nontrivial design requirements and constraints in order to develop a new prototype incubator for clinical trials in hospitals in India. © 2014 Society for Laboratory Automation and Screening.

  10. CONSTRUCTION AND VALIDATION OF LOW COST LAPAROSCOPIC SIMULATOR USING ANDROID SMARTPHONE AND POP CAST AND A LAPTOP.

    Science.gov (United States)

    Vyas, A; Goel, G

    2017-09-01

    Minimal invasive surgery training requires a lot of practice and for this purpose innovative tools are needed to develop methods for practice and training skills outside the operating room. Commercially available devices are readily available but cost effectiveness and availability are major limiting factors in resource limited setting. We present an innovative and cost effective laparoscopic simulator which can be easily manufactured and used for practice of laparoscopic surgery. Using a free android application, such as IP webcam we can relay video to laptop without the use of any cables and uniquely we use the flash of a camera as the light source and a selfie stick for movement of the camera. Use of this type of setup can help to reduce cost of simulated learning in low income countries and makes laparoscopic training facilities readily available. Copyright© Authors.

  11. Analysis on Occupants’ Satisfaction for Safety Performance Assessment in Low Cost Housing

    Directory of Open Access Journals (Sweden)

    Husin Husrul Nizam

    2014-01-01

    Full Text Available The delivery performance of the low cost housing is questioned since the occupants are prone towards safety hazards in the housing complex, such as structural instability and falling building fragments. Without defining the occupants’ requirements for the development of low cost housing, the prevailing safety factors are hard to be determined. This paper explores the rationale of safety performance assessment in the low cost housing by considering the occupants’ participation to achieve a better safety provision during occupancy period. Questionnaire survey was distributed to 380 occupants of the low cost housing in Kuala Lumpur and Selangor, Malaysia. The result shows that 80.8% of the respondents had expressed their dissatisfaction with the safety performance of the lift. By referring to the mode of ranking level, the most significant aspect rated by the respondents is Building Safety Features, with 51.6% respondents. The attained aspects can be fundamental parameters which can be considered in the future development of low cost housing.

  12. Waste Management Facilities cost information for low-level waste

    Energy Technology Data Exchange (ETDEWEB)

    Shropshire, D.; Sherick, M.; Biadgi, C.

    1995-06-01

    This report contains preconceptual designs and planning level life-cycle cost estimates for managing low-level waste. The report`s information on treatment, storage, and disposal modules can be integrated to develop total life-cycle costs for various waste management options. A procedure to guide the US Department of Energy and its contractor personnel in the use of cost estimation data is also summarized in this report.

  13. AUTOMATED LOW-COST PHOTOGRAMMETRY FOR FLEXIBLE STRUCTURE MONITORING

    Directory of Open Access Journals (Sweden)

    C. H. Wang

    2012-07-01

    Full Text Available Structural monitoring requires instruments which can provide high precision and accuracy, reliable measurements at good temporal resolution and rapid processing speeds. Long-term campaigns and flexible structures are regarded as two of the most challenging subjects in monitoring engineering structures. Long-term monitoring in civil engineering is generally considered to be labourintensive and financially expensive and it can take significant effort to arrange the necessary human resources, transportation and equipment maintenance. When dealing with flexible structure monitoring, it is of paramount importance that any monitoring equipment used is able to carry out rapid sampling. Low cost, automated, photogrammetric techniques therefore have the potential to become routinely viable for monitoring non-rigid structures. This research aims to provide a photogrammetric solution for long-term flexible structural monitoring purposes. The automated approach was achieved using low-cost imaging devices (mobile phones to replace traditional image acquisition stations and substantially reduce the equipment costs. A self-programmed software package was developed to deal with the hardware-software integration and system operation. In order to evaluate the performance of this low-cost monitoring system, a shaking table experiment was undertaken. Different network configurations and target sizes were used to determine the best configuration. A large quantity of image data was captured by four DSLR cameras and four mobile phone cameras respectively. These image data were processed using photogrammetric techniques to calculate the final results for the system evaluation.

  14. Low cost balancing unit design

    Science.gov (United States)

    Golembiovsky, Matej; Dedek, Jan; Slanina, Zdenek

    2017-06-01

    This article deals with the design of a low-cost balancing system which consist of battery balancing units, accumulator pack units and coordinator unit with interface for higher level of battery management system. This solution allows decentralized mode of operation and the aim of this work is implementation of controlling and diagnostic mechanism into an electric scooter project realized at Technical university of Ostrava. In todays world which now fully enjoys the prime of electromobility, off-grid battery systems and other, it is important to seek the optimal balance between functionality and the economy side of BMS that being electronics which deals with secondary cells of batery packs. There were numerous sophisticated, but not too practical BMS models in the past, such as centralized system or standalone balance modules of individual cells. This article aims at development of standalone balance modules which are able to communicate with the coordinator, adjust their parameters and ensure their cells safety in case of a communication failure. With the current worldwide cutting cost trend in mind, the emphasis was put on the lowest price possible for individual component. The article is divided into two major categories, the first one being desing of power electronics with emphasis on quality, safety (cooling) and also cost. The second part describes development of a communication interface with reliability and cost in mind. The article contains numerous graphs from practical measurements. The outcome of the work and its possible future is defined in the conclusion.

  15. Construction of a low-cost luximeter

    Science.gov (United States)

    Pedroso, L. S.; de Macedo, J. A.; de Araújo, M. S. T.; Voelzke, M. R.

    2016-04-01

    This paper proposes the construction of an electronic instrument called digital luximeter, combining simplicity and low cost, making it simpler and cheaper than those on the market. Its construction tends to facilitate dissemination and access to this type of measuring instrument between high school teachers and educational institutions, making it ideal to be a science lab.

  16. INTEGRATION OF COST MODELS AND PROCESS SIMULATION TOOLS FOR OPTIMUM COMPOSITE MANUFACTURING PROCESS

    Energy Technology Data Exchange (ETDEWEB)

    Pack, Seongchan [General Motors; Wilson, Daniel [General Motors; Aitharaju, Venkat [General Motors; Kia, Hamid [General Motors; Yu, Hang [ESI, Group.; Doroudian, Mark [ESI Group

    2017-09-05

    Manufacturing cost of resin transfer molded composite parts is significantly influenced by the cycle time, which is strongly related to the time for both filling and curing of the resin in the mold. The time for filling can be optimized by various injection strategies, and by suitably reducing the length of the resin flow distance during the injection. The curing time can be reduced by the usage of faster curing resins, but it requires a high pressure injection equipment, which is capital intensive. Predictive manufacturing simulation tools that are being developed recently for composite materials are able to provide various scenarios of processing conditions virtually well in advance of manufacturing the parts. In the present study, we integrate the cost models with process simulation tools to study the influence of various parameters such as injection strategies, injection pressure, compression control to minimize high pressure injection, resin curing rate, and demold time on the manufacturing cost as affected by the annual part volume. A representative automotive component was selected for the study and the results are presented in this paper

  17. Cost-effectiveness evaluation of an RCT in rehabilitation after lumbar spinal fusion: a low-cost, behavioural approach is cost-effective over individual exercise therapy

    DEFF Research Database (Denmark)

    Søgaard, Rikke; Laurberg, Ida; Christensen, Finn B

    2008-01-01

    Recently, Christensen et al. reported the clinical effects of a low-cost rehabilitation program equally efficient to a relatively intensive program of individual, physiotherapist-guided exercise therapy. Yet, the low-cost approach is not fully supported as an optimal strategy until a full......-scale economic evaluation, including extra-hospital effects such as service utilization in the primary health care sector and return-to-work, is conducted. The objective of this study was to conduct such evaluation i.e. investigate the cost-effectiveness of (1) a low-cost rehabilitation regimen...... with a behavioural element and (2) a regimen of individual exercise therapy, both in comparison with usual practice, from a health economic, societal perspective. Study design was a cost-effectiveness evaluation of an RCT with a 2-year follow-up. Ninety patients having had posterolateral or circumferential fusion...

  18. System identification of a small low-cost unmanned aerial vehicle using flight data from low-cost sensors

    Science.gov (United States)

    Hoffer, Nathan Von

    Remote sensing has traditionally been done with satellites and manned aircraft. While. these methods can yield useful scientificc data, satellites and manned aircraft have limitations in data frequency, process time, and real time re-tasking. Small low-cost unmanned aerial vehicles (UAVs) provide greater possibilities for personal scientic research than traditional remote sensing platforms. Precision aerial data requires an accurate vehicle dynamics model for controller development, robust flight characteristics, and fault tolerance. One method of developing a model is system identification (system ID). In this thesis system ID of a small low-cost fixed-wing T-tail UAV is conducted. The linerized longitudinal equations of motion are derived from first principles. Foundations of Recursive Least Squares (RLS) are presented along with RLS with an Error Filtering Online Learning scheme (EFOL). Sensors, data collection, data consistency checking, and data processing are described. Batch least squares (BLS) and BLS with EFOL are used to identify aerodynamic coecoefficients of the UAV. Results of these two methods with flight data are discussed.

  19. Technical considerations for designing low-cost, long-wave infrared objectives

    Science.gov (United States)

    Desroches, Gerard; Dalzell, Kristy; Robitaille, Blaise

    2014-06-01

    With the growth of uncooled infrared imaging in the consumer market, the balance between cost implications and performance criteria in the objective lens must be examined carefully. The increased availability of consumer-grade, long-wave infrared cameras is related to a decrease in military usage but it is also due to the decreasing costs of the cameras themselves. This has also driven up demand for low-cost, long-wave objectives that can resolve smaller pixels while maintaining high performance. Smaller pixels are traditionally associated with high cost objectives because of higher resolution requirements but, with careful consideration of all the requirements and proper selection of materials, costs can be moderated. This paper examines the cost/performance trade-off implications associated with optical and mechanical requirements of long-wave infrared objectives. Optical performance, f-number, field of view, distortion, focus range and thermal range all affect the cost of the objective. Because raw lens material cost is often the most expensive item in the construction, selection of the material as well as the shape of the lens while maintaining acceptable performance and cost targets were explored. As a result of these considerations, a low-cost, lightweight, well-performing objective was successfully designed, manufactured and tested.

  20. MOCA: A Low-Power, Low-Cost Motion Capture System Based on Integrated Accelerometers

    Directory of Open Access Journals (Sweden)

    Elisabetta Farella

    2007-01-01

    Full Text Available Human-computer interaction (HCI and virtual reality applications pose the challenge of enabling real-time interfaces for natural interaction. Gesture recognition based on body-mounted accelerometers has been proposed as a viable solution to translate patterns of movements that are associated with user commands, thus substituting point-and-click methods or other cumbersome input devices. On the other hand, cost and power constraints make the implementation of a natural and efficient interface suitable for consumer applications a critical task. Even though several gesture recognition solutions exist, their use in HCI context has been poorly characterized. For this reason, in this paper, we consider a low-cost/low-power wearable motion tracking system based on integrated accelerometers called motion capture with accelerometers (MOCA that we evaluated for navigation in virtual spaces. Recognition is based on a geometric algorithm that enables efficient and robust detection of rotational movements. Our objective is to demonstrate that such a low-cost and a low-power implementation is suitable for HCI applications. To this purpose, we characterized the system from both a quantitative point of view and a qualitative point of view. First, we performed static and dynamic assessment of movement recognition accuracy. Second, we evaluated the effectiveness of user experience using a 3D game application as a test bed.

  1. Design of a low-cost hybrid powertrain with large fuel savings

    NARCIS (Netherlands)

    Berkel, van K.; Romers, L.H.J.; Vroemen, B.G.; Hofman, T.; Steinbuch, M.

    2010-01-01

    This paper presents a new design of a low-cost hybrid powertrain with large fuel savings. The hybrid powertrain contains only low-cost mechanical components, such as a flywheel module and a continuously variable transmission (CVT). Noelectrical motor/generator or battery is used. Based on

  2. Providing strong Security and high privacy in low-cost RFID networks

    DEFF Research Database (Denmark)

    David, Mathieu; Prasad, Neeli R.

    2009-01-01

    Since the dissemination of Radio Frequency IDentification (RFID) tags is getting larger and larger, the requirement for strong security and privacy is also increasing. Low-cost and ultra-low-cost tags are being implemented on everyday products, and their limited resources constraints the security...

  3. Low-cost production of solar-cell panels

    Science.gov (United States)

    Bickler, D. B.; Gallagher, B. D.; Sanchez, L. E.

    1980-01-01

    Large-scale production model combines most modern manufacturing techniques to produce silicon-solar-cell panels of low costs by 1982. Model proposes facility capable of operating around the clock with annual production capacity of 20 W of solar cell panels.

  4. Sensorless control of low-cost single-phase hybrid switched reluctance motor drive

    DEFF Research Database (Denmark)

    Jakobsen, Uffe; Lu, Kaiyuan; Rasmussen, Peter Omand

    2013-01-01

    This paper presents a sensorless-controlled, low-cost, low-power, variable-speed drive system suitable for fan and pump applications. The main advantages of this drive system are the low system cost, simple converter structure, and simple but robust sensorless control technique. The drive motor...... is a special Hybrid Switched Reluctance Motor (HSRM). The proposed sensorless control method utilizes beneficially the stator side permanent magnet field and its performance is motor parameter independent. The unique low-cost drive system solution, simple and robust sensorless control features of this drive...

  5. Sensorless Control of Low-cost Single-phase Hybrid Switched Reluctance Motor Drive

    DEFF Research Database (Denmark)

    Jakobsen, Uffe; Lu, Kaiyuan; Rasmussen, Peter Omand

    2015-01-01

    This paper presents a sensorless-controlled, low-cost, low-power, and variable-speed drive system suitable for fan and pump applications. The main advantages of this drive system are the low system cost, simple converter structure, and simple but robust sensorless control technique. The drive motor...... is a special hybrid switched reluctance motor. The proposed sensorless control method beneficially utilizes the stator side PM field and its performance is motor parameter independent. The unique low-cost drive system solution, simple and robust sensorless control features of this drive system, is demonstrated...

  6. Cost-effective and low-technology options for simulation and training in neonatology.

    Science.gov (United States)

    Bruno, Christie J; Glass, Kristen M

    2016-11-01

    The purpose of this review is to explore low-cost options for simulation and training in neonatology. Numerous cost-effective options exist for simulation and training in neonatology. Lower cost options are available for teaching clinical skills and procedural training in neonatal intubation, chest tube insertion, and pericardiocentesis, among others. Cost-effective, low-cost options for simulation-based education can be developed and shared in order to optimize the neonatal simulation training experience. Copyright © 2016 Elsevier Inc. All rights reserved.

  7. A low-cost touchscreen operant chamber using a Raspberry Pi™.

    Science.gov (United States)

    O'Leary, James D; O'Leary, Olivia F; Cryan, John F; Nolan, Yvonne M

    2018-03-08

    The development of a touchscreen platform for rodent testing has allowed new methods for cognitive testing that have been back-translated from clinical assessment tools to preclinical animal models. This platform for cognitive assessment in animals is comparable to human neuropsychological tests such as those employed by the Cambridge Neuropsychological Test Automated Battery, and thus has several advantages compared to the standard maze apparatuses typically employed in rodent behavioral testing, such as the Morris water maze. These include improved translation of preclinical models, as well as high throughput and the automation of animal testing. However, these systems are relatively expensive, which can impede progress for researchers with limited resources. Here we describe a low-cost touchscreen operant chamber based on the single-board computer, Raspberry Pi TM , which is capable of performing tasks similar to those supported by current state-of-the-art systems. This system provides an affordable alternative for cognitive testing in a touchscreen operant paradigm for researchers with limited funding.

  8. Low Cost Night Vision System for Intruder Detection

    Science.gov (United States)

    Ng, Liang S.; Yusoff, Wan Azhar Wan; R, Dhinesh; Sak, J. S.

    2016-02-01

    The growth in production of Android devices has resulted in greater functionalities as well as lower costs. This has made previously more expensive systems such as night vision affordable for more businesses and end users. We designed and implemented robust and low cost night vision systems based on red-green-blue (RGB) colour histogram for a static camera as well as a camera on an unmanned aerial vehicle (UAV), using OpenCV library on Intel compatible notebook computers, running Ubuntu Linux operating system, with less than 8GB of RAM. They were tested against human intruders under low light conditions (indoor, outdoor, night time) and were shown to have successfully detected the intruders.

  9. Development of Innovative Technology to Provide Low-Cost Surface Atmospheric Observations

    Science.gov (United States)

    Kucera, Paul; Steinson, Martin

    2016-04-01

    Accurate and reliable real-time monitoring and dissemination of observations of surface weather conditions is critical for a variety of societal applications. Applications that provide local and regional information about temperature, precipitation, moisture, and winds, for example, are important for agriculture, water resource monitoring, health, and monitoring of hazard weather conditions. In many regions in Africa (and other global locations), surface weather stations are sparsely located and/or of poor quality. Existing stations have often been sited incorrectly, not well-maintained, and have limited communications established at the site for real-time monitoring. The US National Weather Service (NWS) International Activities Office (IAO) in partnership with University Corporation for Atmospheric Research (UCAR)/National Center for Atmospheric Research (NCAR) and funded by the United States Agency for International Development (USAID) Office of Foreign Disaster Assistance (OFDA) has started an initiative to develop and deploy low-cost weather instrumentation in sparsely observed regions of the world. The goal is to provide observations for environmental monitoring, and early warning alert systems that can be deployed at weather services in developing countries. Instrumentation is being designed using innovative new technologies such as 3D printers, Raspberry Pi computing systems, and wireless communications. The initial effort is focused on designing a surface network using GIS-based tools, deploying an initial network in Zambia, and providing training to Zambia Meteorological Department (ZMD) staff. The presentation will provide an overview of the project concepts, design of the low cost instrumentation, and initial experiences deploying a surface network deployment in Zambia.

  10. Mars Relay Satellite: Key to Enabling Low-Cost Exploration Missions

    Science.gov (United States)

    Hastrup, R.; Cesarone, R.; Miller, A.

    1993-01-01

    Recently, there has been increasing evidence of a renewed focus on Mars exploration both by NASA and the international community. The thrust of this renewed interest appears to be manifesting itself in numerous low-cost missions employing small, light weight elements, which utilize advanced technologies including integrated microelectronics. A formidable problem facing these low-cost missions is communications with Earth. Providing adequate direct-link performance has very significant impacts on spacecraft power, pointing, mass and overall complexity. Additionally, for elements at or near the surface of Mars, there are serious connectivity constraints, especially at higher latitudes, which lose view of Earth for up to many months at a time. This paper will discuss the role a Mars relay satellite can play in enabling and enhancing low-cost missions to Mars...

  11. A low-cost, high-resolution, video-rate imaging optical radar

    Energy Technology Data Exchange (ETDEWEB)

    Sackos, J.T.; Nellums, R.O.; Lebien, S.M.; Diegert, C.F. [Sandia National Labs., Albuquerque, NM (United States); Grantham, J.W.; Monson, T. [Air Force Research Lab., Eglin AFB, FL (United States)

    1998-04-01

    Sandia National Laboratories has developed a unique type of portable low-cost range imaging optical radar (laser radar or LADAR). This innovative sensor is comprised of an active floodlight scene illuminator and an image intensified CCD camera receiver. It is a solid-state device (no moving parts) that offers significant size, performance, reliability, and simplicity advantages over other types of 3-D imaging sensors. This unique flash LADAR is based on low cost, commercially available hardware, and is well suited for many government and commercial uses. This paper presents an update of Sandia`s development of the Scannerless Range Imager technology and applications, and discusses the progress that has been made in evolving the sensor into a compact, low, cost, high-resolution, video rate Laser Dynamic Range Imager.

  12. The value of Standards and Labelling: an international cost-benefit analysis tool for Standards and Labelling programs with results for Central American countries

    International Nuclear Information System (INIS)

    Buskirk, Robert D. Van; McNeil, Michael A.; Letschert, Virginie E.

    2005-01-01

    We describe a cost-benefit spreadsheet analysis tool that provides an evaluation of the net impacts of an appliance standards and labelling (SandL) program. The tool is designed to provide a rough estimate at very low cost to local analysts, while allowing for a more accurate evaluation when detailed local data are available. The methodology takes a bottom-up engineering approach, beginning with appliance-specific engineering parameters relating efficiency improvement and incremental costs associated with specific design technologies. Efficiency improvement afforded by each potential policy option is combined with local appliance use patterns to estimate average annual energy consumption for each appliance. This information is combined with appliance lifetime data and local energy prices to provide a life cycle cost impact assessment at the household level. In addition to household level impacts, the analysis tool forecasts future appliance sales, in order to calculate potential energy savings, consumer financial impacts and carbon emissions reductions at the national level. In order to demonstrate the features of the policy model employed, this poster presents a regional analysis based on the most recent publicly available appliance data. In particular, a set of developing countries in Central America were chosen as an example. Taken as a whole, the Central American results demonstrate the general level of benefit which could be afforded in these countries. Comparison between the countries reveals the key parameters determining the benefit a given country can expect from a standards program

  13. A Low-Cost, High-Precision Navigator, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — Toyon Research Corporation proposes to develop and demonstrate a prototype low-cost precision navigation system using commercial-grade gyroscopes and accelerometers....

  14. Low-cost amplifier for alpha detection with photodiode

    Energy Technology Data Exchange (ETDEWEB)

    Domienikan, Cláudio; Costa, Priscila; Genezini, Frederico A.; Zahn, Guilherme S., E-mail: clanikan@ipen.br, E-mail: pcosta@ipen.br, E-mail: fredzini@ipen.br, E-mail: gzahn@ipen.br [Instituto de Pesquisas Energéticas e Nucleares (IPEN/CNEN-SP), São Paulo, SP (Brazil)

    2017-07-01

    A low-cost amplifier for Hamamatsu S3590-09 PIN photodiode to be used in alpha detection is presented. This amplifier consists basically of two circuits: a pulse preamplifier and a shaper-driver. The PIN photodiode is reverse-biased and connected to a charge preamplifier input. Incident alpha particles generate a small current pulse in the photodiode. The integrating circuit of the low noise preamplifier transforms current pulse into a voltage pulse with amplitude proportional to the charge carried by the current pulse. The shaper-driver consists of a differentiator and an integrator and is responsible for filtering and further amplifying the preamplifier signal, generating a NIM-compatible energy pulse. The performance of the set photodiode-amplifier was successively tested through the use of a {sup 243}Am radioactive source. The low-cost photodiode amplifier was designed and constructed at IPEN - CNEN/SP using national components and expertise. (author)

  15. APPLICATION AND DEVELOPMENT OF APPROPRIATE TOOLS AND TECHNOLOGIES FOR COST-EFFECTIVE CARBON

    Energy Technology Data Exchange (ETDEWEB)

    Bill Stanley; Sandra Brown; Ellen Hawes; Zoe Kant; Miguel Calmon; Patrick Gonzalez; Brad Kreps; Gilberto Tiepolo

    2003-09-01

    The Nature Conservancy is participating in a Cooperative Agreement with the Department of Energy (DOE) National Energy Technology Laboratory (NETL) to explore the compatibility of carbon sequestration in terrestrial ecosystems and the conservation of biodiversity. The title of the research project is ''Application and Development of Appropriate Tools and Technologies for Cost-Effective Carbon Sequestration''. The objectives of the project are to: (1) improve carbon offset estimates produced in both the planning and implementation phases of projects; (2) build valid and standardized approaches to estimate project carbon benefits at a reasonable cost; and (3) lay the groundwork for implementing cost-effective projects, providing new testing ground for biodiversity protection and restoration projects that store additional atmospheric carbon. This Technical Progress Report discusses preliminary results of the six specific tasks that The Nature Conservancy is undertaking to answer research needs while facilitating the development of real projects with measurable greenhouse gas impacts. The research described in this report occurred between July 1, 2002 and June 30, 2003. The specific tasks discussed include: Task 1: carbon inventory advancements; Task 2: advanced videography testing; Task 3: baseline method development; Task 4: third-party technical advisory panel meetings; Task 5: new project feasibility studies; and Task 6: development of new project software screening tool.

  16. Fundamental understanding and development of low-cost, high-efficiency silicon solar cells

    Energy Technology Data Exchange (ETDEWEB)

    ROHATGI,A.; NARASIMHA,S.; MOSCHER,J.; EBONG,A.; KAMRA,S.; KRYGOWSKI,T.; DOSHI,P.; RISTOW,A.; YELUNDUR,V.; RUBY,DOUGLAS S.

    2000-05-01

    The overall objectives of this program are (1) to develop rapid and low-cost processes for manufacturing that can improve yield, throughput, and performance of silicon photovoltaic devices, (2) to design and fabricate high-efficiency solar cells on promising low-cost materials, and (3) to improve the fundamental understanding of advanced photovoltaic devices. Several rapid and potentially low-cost technologies are described in this report that were developed and applied toward the fabrication of high-efficiency silicon solar cells.

  17. Application of Low-Cost Fixed-Wing UAV for Inland Lakes Shoreline Investigation

    Science.gov (United States)

    Templin, Tomasz; Popielarczyk, Dariusz; Kosecki, Rafał

    2017-10-01

    One of the most important factors that influences the performance of geomorphologic parameters on urban lakes is the water level. It fluctuates periodically, causing shoreline changes. It is especially significant for typical environmental studies like bathymetric surveys, morphometric parameters calculation, sediment depth changes, thermal structure, water quality monitoring, etc. In most reservoirs, it can be obtained from digitized historical maps or plans or directly measured using the instruments such as: geodetic total station, GNSS receivers, UAV with different sensors, satellite and aerial photos, terrestrial and airborne light detection and ranging, or others. Today one of the most popular measuring platforms, increasingly applied in many applications is UAV. Unmanned aerial system can be a cheap, easy to use, on-demand technology for gathering remote sensing data. Our study presents a reliable methodology for shallow lake shoreline investigation with the use of a low-cost fixed-wing UAV system. The research was implemented on a small, eutrophic urban inland reservoir located in the northern part of Poland—Lake Suskie. The geodetic TS, and RTK/GNSS measurements, hydroacoustic soundings and experimental aerial mapping were conducted by the authors in 2012-2015. The article specifically describes the UAV system used for experimental measurements, the obtained results and the accuracy analysis. Final conclusions demonstrate that even a low-cost fixed-wing UAV can provide an excellent tool for accurately surveying a shallow lake shoreline and generate valuable geoinformation data collected definitely faster than when traditional geodetic methods are employed.

  18. Producing optical (contact) lenses by a novel low cost process

    Science.gov (United States)

    Skipper, Richard S.; Spencer, Ian D.

    2005-09-01

    The rapid and impressive growth of China has been achieved on the back of highly labour intensive industries, often in manufacturing, and at the cost of companies and jobs in Europe and America. Approaches that worked well in the 1990's to reduce production costs in the developed countries are no longer effective when confronted with the low labour costs of China and India. We have looked at contact lenses as a product that has become highly available to consumers here but as an industry that has reduced costs by moving to low labour cost countries. The question to be answered was, "Do we have the skill to still make the product in the UK, and can we make it cheap enough to export to China?" if we do not, then contact lens manufacture will move to China sooner or later. The challenge to enter the markets of the BRIC (Brazil, Russia, India and China) countries is extremely exciting as here is the new money, high growth and here is a product that sells to those with disposable incomes. To succeed we knew we had to be radical in our approach; the radical step was very simple: to devise a process in which each step added value to the customer and not cost to the product. The presentation examines the processes used by the major producers and how, by applying good manufacturing practice sound scientific principles to them, the opportunity to design a new low cost patented process was identified.

  19. Low-cost wireless voltage & current grid monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Hines, Jacqueline [SenSanna Inc., Arnold, MD (United States)

    2016-12-31

    This report describes the development and demonstration of a novel low-cost wireless power distribution line monitoring system. This system measures voltage, current, and relative phase on power lines of up to 35 kV-class. The line units operate without any batteries, and without harvesting energy from the power line. Thus, data on grid condition is provided even in outage conditions, when line current is zero. This enhances worker safety by detecting the presence of voltage and current that may appear from stray sources on nominally isolated lines. Availability of low-cost power line monitoring systems will enable widespread monitoring of the distribution grid. Real-time data on local grid operating conditions will enable grid operators to optimize grid operation, implement grid automation, and understand the impact of solar and other distributed sources on grid stability. The latter will enable utilities to implement eneygy storage and control systems to enable greater penetration of solar into the grid.

  20. A Low Cost Single Chip VDL Compatible Transceiver ASIC

    Science.gov (United States)

    Becker, Robert

    2004-01-01

    Recent trends in commercial communications system components have focussed almost exclusively on cellular telephone technology. As many of the traditional sources of receiver components have discontinued non-cellular telephone products, the designers of avionics and other low volume radio applications find themselves increasingly unable to find highly integrated components. This is particularly true for low power, low cost applications which cannot afford the lavish current consumption of the software defined radio approach increasingly taken by certified device manufacturers. In this paper, we describe a low power transceiver chip targeting applications from low VHF to low UHF frequencies typical of avionics systems. The chip encompasses a selectable single or double conversion design for the receiver and a low power IF upconversion transmitter. All local oscillators are synthesized and integrated into the chip. An on-chip I-Q modulator and demodulator provide baseband modulation and demodulation capability allowing the use of low power, fixed point signal processing components for signal demodulation. The goal of this program is to demonstrate a low cost VDL mode-3 transceiver using this chip to receive text weather information sent using 4-slot TDMA with no support for voice. The data will be sent from an experimental ground station. This work is funded by NASA Glenn Research Center.

  1. Prosthetic design directives: Low-cost hands within reach.

    Science.gov (United States)

    Jones, G K; Rosendo, A; Stopforth, R

    2017-07-01

    Although three million people around the world suffer from the lack of one or both upper limbs 80% of this number is located within developing countries. While prosthetic prices soar with technology 3D printing and low cost electronics present a sensible solution for those that cannot afford expensive prosthetics. The electronic and control design of a low-cost prosthetic hand, the Touch Hand II, is discussed. This paper shows that sensorless techniques can be used to reduce design complexities, costs, and provide easier access to the electronics. A closing and opening finite state machine (COFSM) was developed to handle the actuated digit joint control state and a supervisory switching control scheme, used for speed and grip strength control. Three torque and speed settings were created to be preset for specific grasps. The hand was able to replicate ten frequently used grasps and grip some common objects. Future work is necessary to enable a user to control it with myoelectric signals (MESs) and to solve operational problems related to electromagnetic interference (EMI).

  2. Digital Image Quantitative Evaluations for Low Cost Film Digitizers Height Determination

    International Nuclear Information System (INIS)

    Khairul Anuar Mohd Salleh; Arshad Yassin; Ahmad Nasir Yusof; Noorhazleena Azaman

    2016-01-01

    Non Destructive Testing (NDT) technology contributes significant improvement to the quality of industrial products, and the integrity of equipment and plants. Introduction of powerful computers and reliable imaging technology has had significant impact on the traditional nuclear based NDT technology. Demand for faster, reliable, low cost, and flexible technology is rapidly increased. With the growing demand for more efficient digital archiving, digital image analysis, and reporting results with a low cost technology, one cannot deny the importance of having another cheaper solution. This project will apply fundamental principle of image digitization to be used in building up a low cost film digitization solution. The height of the film digitization was carefully determined by examining each digital images produced. Three (3) repetitive quantitative evaluations (Modulation Transfer Function [MTF], Characteristic Transfer Curve [CTC], and Contrast to Noise Ratio [CNR]) were performed at different condition to assist with the determination of the low cost film digitizers height. All 3 evaluations were successfully applied and the most appropriate height was successfully determined. (author)

  3. Synthesis and characterization of low cost magnetorheological (MR) fluids

    Science.gov (United States)

    Sukhwani, V. K.; Hirani, H.

    2007-04-01

    Magnetorheological fluids have great potential for engineering applications due to their variable rheological behavior. These fluids find applications in dampers, brakes, shock absorbers, and engine mounts. However their relatively high cost (approximately US600 per liter) limits their wide usage. Most commonly used magnetic material "Carbonyl iron" cost more than 90% of the MR fluid cost. Therefore for commercial viability of these fluids there is need of alternative economical magnetic material. In the present work synthesis of MR fluid has been attempted with objective to produce low cost MR fluid with high sedimentation stability and greater yield stress. In order to reduce the cost, economical electrolytic Iron powder (US 10 per Kg) has been used. Iron powder of relatively larger size (300 Mesh) has been ball milled to reduce their size to few microns (1 to 10 microns). Three different compositions have been prepared and compared for MR effect produced and stability. All have same base fluid (Synthetic oil) and same magnetic phase i.e. Iron particles but they have different additives. First preparation involves organic additives Polydimethylsiloxane (PDMS) and Stearic acid. Other two preparations involve use of two environmental friendly low-priced green additives guar gum (US 2 per Kg) and xanthan gum (US 12 per Kg) respectively. Magnetic properties of Iron particles have been measured by Vibrating Sample Magnetometer (VSM). Morphology of Iron particles and additives guar gum and xanthan gum has been examined by Scanning Electron Microscopy (SEM) and Particles Size Distribution (PSD) has been determined using Particle size analyzer. Microscopic images of particles, MH plots and stability of synthesized MR fluids have been reported. The prepared low cost MR fluids showed promising performance and can be effectively used for engineering applications demanding controllability in operations.

  4. Design of a Low-cost Oil Spill Tracking Buoy

    Science.gov (United States)

    Zhao, Y.; Hu, X.; Yu, F.; Dong, S.; Chen, G.

    2017-12-01

    As the rapid development of oil exploitation and transportation, oil spill accidents, such as Prestige oil spill, Gulf of Mexico oil spill accident and so on, happened frequently in recent years which would result in long-term damage to the environment and human life. It would be helpful for rescue operation if we can locate the oil slick diffusion area in real time. Equipped with GNSS system, current tracking buoys(CTB), such as Lagrangian drifting buoy, Surface Velocity Program (SVP) drifter, iSLDMB (Iridium self locating datum marker buoy) and Argosphere buoy, have been used as oil tracking buoy in oil slick observation and as validation tools for oil spill simulation. However, surface wind could affect the movement of oil slick, which couldn't be reflected by CTB, thus the oil spill tracking performance is limited. Here, we proposed an novel oil spill tracking buoy (OSTB) which has a low cost of less than $140 and is equipped with Beidou positioning module and sails to track oil slick. Based on hydrodynamic equilibrium model and ocean dynamic analysis, the wind sails and water sails are designed to be adjustable according to different marine conditions to improve tracking efficiency. Quick release device is designed to assure easy deployment from air or ship. Sea experiment was carried out in Jiaozhou Bay, Northern China. OSTB, SVP, iSLDMB, Argosphere buoy and a piece of oil-simulated rubber sheet were deployed at the same time. Meanwhile, oil spill simulation model GNOME (general NOAA operational modeling environment) was configured with the wind and current field, which were collected by an unmanned surface vehicle (USV) mounted with acoustic Doppler current profilers (ADCP) and wind speed and direction sensors. Experimental results show that the OSTB has better relevance with rubber sheet and GNOME simulation results, which validate the oil tracking ability of OSTB. With low cost and easy deployment, OSTB provides an effective way for oil spill numerical

  5. Low-Cost Experimentation for the Study of Droplet Microfluidics

    Science.gov (United States)

    Bardin, David; Lee, Abraham P.

    2014-01-01

    The continued growth of microfluidics into industry settings in areas such as point-of-care diagnostics and targeted therapeutics necessitates a workforce trained in microfluidic technologies and experimental methods. Laboratory courses for students at the university and high school levels will require cost-effective in-class demonstrations that instruct in chip design, fabrication, and experimentation at the microscale. We present a hand-operated pressure pumping system to form monodisperse picoliter to nanoliter droplet streams at low cost, and a series of exercises aimed at instructing in the specific art of droplet formation. Using this setup, the student is able to generate and observe the modes of droplet formation in flow-focusing devices, and the effect of device dimensions on the characteristics of formed droplets. Lastly, at ultra-low cost we demonstrate large plug formation in a T-junction using coffee stirrers as a master mold substitute. Our method reduces the cost of experimentation to enable intuitive instruction in droplet formation, with additional implications for creating droplets in the field or at point-of-care. PMID:25133595

  6. Low-cost evacuated-tube solar collector. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Beecher, D. T.

    1981-02-10

    A prototype design for an evacuated tube air cooled solar collector module has been completed. A product cost study, based on the production of 60,000 of the prototype modules per year (approx. 1,000,000 square feet annually), estimates that the module as shipped would have a cost at inventory of $7.09 to $7.40 per square foot of aperture. Computer programs were developed to predict the optical and thermal performance of the module. Antireflective coatings (porous aluminum oxide) which could be formed by spraying or dipping were demonstrated but degraded more rapidly when exposed to a high humidity ambient than acid etched films. A selective black chromium oxide multi-layered graded film was vapor deposited which had an absorptivity of about 0.9 and an emissivity of 0.03. When the film was heated to temperatures of 400/sup 0/C in a gettered vacuum for as little as 24 hours, however, irreversible changes took place both between and within coating layers which resulted in ..cap alpha.. decreasing to about 0.73 and epsilon increasing to 0.14. The product cost studies indicate that module design changes are warranted to reduce product cost prior to tooling for production.

  7. International Assistance for Low-Emission Development Planning: Coordinated Low Emissions Assistance Network (CLEAN) Inventory of Activities and Tools--Preliminary Trends

    Energy Technology Data Exchange (ETDEWEB)

    Cox, S.; Benioff, R.

    2011-05-01

    The Coordinated Low Emissions Assistance Network (CLEAN) is a voluntary network of international practitioners supporting low-emission planning in developing countries. The network seeks to improve quality of support through sharing project information, tools, best practices and lessons, and by fostering harmonized assistance. CLEAN has developed an inventory to track and analyze international technical support and tools for low-carbon planning activities in developing countries. This paper presents a preliminary analysis of the inventory to help identify trends in assistance activities and tools available to support developing countries with low-emission planning.

  8. Application of low-cost methodologies for mobile phone app development.

    Science.gov (United States)

    Zhang, Melvyn; Cheow, Enquan; Ho, Cyrus Sh; Ng, Beng Yeong; Ho, Roger; Cheok, Christopher Cheng Soon

    2014-12-09

    The usage of mobile phones and mobile phone apps in the recent decade has indeed become more prevalent. Previous research has highlighted a method of using just the Internet browser and a text editor to create an app, but this does not eliminate the challenges faced by clinicians. More recently, two methodologies of app development have been shared, but there has not been any disclosures pertaining to the costs involved. In addition, limitations such as the distribution and dissemination of the apps have not been addressed. The aims of this research article are to: (1) highlight a low-cost methodology that clinicians without technical knowledge could use to develop educational apps; (2) clarify the respective costs involved in the process of development; (3) illustrate how limitations pertaining to dissemination could be addressed; and (4) to report initial utilization data of the apps and to share initial users' self-rated perception of the apps. In this study, we will present two techniques of how to create a mobile app using two of the well-established online mobile app building websites. The costs of development are specified and the methodology of dissemination of the apps will be shared. The application of the low-cost methodologies in the creation of the "Mastering Psychiatry" app for undergraduates and "Déjà vu" app for postgraduates will be discussed. A questionnaire survey has been administered to undergraduate students collating their perceptions towards the app. For the Mastering Psychiatry app, a cumulative total of 722 users have used the mobile app since inception, based on our analytics. For the Déjà vu app, there has been a cumulative total of 154 downloads since inception. The utilization data demonstrated the receptiveness towards these apps, and this is reinforced by the positive perceptions undergraduate students (n=185) had towards the low-cost self-developed apps. This is one of the few studies that have demonstrated the low-cost

  9. Implementing a low-cost web-based clinical trial management system for community studies: a case study.

    Science.gov (United States)

    Geyer, John; Myers, Kathleen; Vander Stoep, Ann; McCarty, Carolyn; Palmer, Nancy; DeSalvo, Amy

    2011-10-01

    Clinical trials with multiple intervention locations and a single research coordinating center can be logistically difficult to implement. Increasingly, web-based systems are used to provide clinical trial support with many commercial, open source, and proprietary systems in use. New web-based tools are available which can be customized without programming expertise to deliver web-based clinical trial management and data collection functions. To demonstrate the feasibility of utilizing low-cost configurable applications to create a customized web-based data collection and study management system for a five intervention site randomized clinical trial establishing the efficacy of providing evidence-based treatment via teleconferencing to children with attention-deficit hyperactivity disorder. The sites are small communities that would not usually be included in traditional randomized trials. A major goal was to develop database that participants could access from computers in their home communities for direct data entry. Discussed is the selection process leading to the identification and utilization of a cost-effective and user-friendly set of tools capable of customization for data collection and study management tasks. An online assessment collection application, template-based web portal creation application, and web-accessible Access 2007 database were selected and customized to provide the following features: schedule appointments, administer and monitor online secure assessments, issue subject incentives, and securely transmit electronic documents between sites. Each tool was configured by users with limited programming expertise. As of June 2011, the system has successfully been used with 125 participants in 5 communities, who have completed 536 sets of assessment questionnaires, 8 community therapists, and 11 research staff at the research coordinating center. Total automation of processes is not possible with the current set of tools as each is loosely

  10. Low-Cost Propellant Launch From a Tethered Balloon

    Science.gov (United States)

    Wilcox, Brian

    2006-01-01

    A document presents a concept for relatively inexpensive delivery of propellant to a large fuel depot in low orbit around the Earth, for use in rockets destined for higher orbits, the Moon, and for remote planets. The propellant is expected to be at least 85 percent of the mass needed in low Earth orbit to support the NASA Exploration Vision. The concept calls for the use of many small ( 10 ton) spin-stabilized, multistage, solid-fuel rockets to each deliver 250 kg of propellant. Each rocket would be winched up to a balloon tethered above most of the atmospheric mass (optimal altitude 26 2 km). There, the rocket would be aimed slightly above the horizon, spun, dropped, and fired at a time chosen so that the rocket would arrive in orbit near the depot. Small thrusters on the payload (powered, for example, by boil-off gases from cryogenic propellants that make up the payload) would precess the spinning rocket, using data from a low-cost inertial sensor to correct for small aerodynamic and solid rocket nozzle misalignment torques on the spinning rocket; would manage the angle of attack and the final orbit insertion burn; and would be fired on command from the depot in response to observations of the trajectory of the payload so as to make small corrections to bring the payload into a rendezvous orbit and despin it for capture by the depot. The system is low-cost because the small rockets can be mass-produced using the same techniques as those to produce automobiles and low-cost munitions, and one or more can be launched from a U.S. territory on the equator (Baker or Jarvis Islands in the mid-Pacific) to the fuel depot on each orbit (every 90 minutes, e.g., any multiple of 6,000 per year).

  11. Computational Sensing Using Low-Cost and Mobile Plasmonic Readers Designed by Machine Learning

    KAUST Repository

    Ballard, Zachary S.

    2017-01-27

    Plasmonic sensors have been used for a wide range of biological and chemical sensing applications. Emerging nanofabrication techniques have enabled these sensors to be cost-effectively mass manufactured onto various types of substrates. To accompany these advances, major improvements in sensor read-out devices must also be achieved to fully realize the broad impact of plasmonic nanosensors. Here, we propose a machine learning framework which can be used to design low-cost and mobile multispectral plasmonic readers that do not use traditionally employed bulky and expensive stabilized light sources or high-resolution spectrometers. By training a feature selection model over a large set of fabricated plasmonic nanosensors, we select the optimal set of illumination light-emitting diodes needed to create a minimum-error refractive index prediction model, which statistically takes into account the varied spectral responses and fabrication-induced variability of a given sensor design. This computational sensing approach was experimentally validated using a modular mobile plasmonic reader. We tested different plasmonic sensors with hexagonal and square periodicity nanohole arrays and revealed that the optimal illumination bands differ from those that are “intuitively” selected based on the spectral features of the sensor, e.g., transmission peaks or valleys. This framework provides a universal tool for the plasmonics community to design low-cost and mobile multispectral readers, helping the translation of nanosensing technologies to various emerging applications such as wearable sensing, personalized medicine, and point-of-care diagnostics. Beyond plasmonics, other types of sensors that operate based on spectral changes can broadly benefit from this approach, including e.g., aptamer-enabled nanoparticle assays and graphene-based sensors, among others.

  12. Development of a low cost, low temperature cryocooler using the Gifford McMahon cycle

    Science.gov (United States)

    Ramanayaka, A.; Mani, R.

    2008-03-01

    Although Helium is the second most abundant element, its concentration in the earth's atmosphere is fairly low and constant, as the portion that escapes from the atmosphere is replace by new emission. Historically, Helium was extracted as a byproduct of natural gas production, and stored in gas fields in a National Helium Reserve, in an attempt to conserve this interesting element. National policy has changed and the cost of liquid Helium has increased rapidly in the recent past. These new circumstances have created new interest in alternative eco-friendly methods to realizing and maintaining low temperatures in the laboratory. There have been number of successful attempts at making low temperature closed cycle Helium refrigerators by modifying an existing closed cycle system, and usually the regenerator has been replaced in order to achieve the desired results. Here, we discus our attempt to fabricate a low cost, low temperature closed cycle Helium refrigerator starting from a 15K Gifford McMahon system. We reexamine the barriers to realizing lower temperature here and our attempts at overcoming them.

  13. Design for Six Sigma: Approach for reliability and low-cost manufacturing.

    Directory of Open Access Journals (Sweden)

    Jesus Gerardo Cruz Alvarez

    2012-07-01

    Full Text Available The aim of this study is to discuss new product development based on a traditional stage-gate process and to examine how new product development [NPD] tools, such as lean design for Six Sigma, can accelerate the achievement of the main goals of NPD: reliable product quality, cost-effective implementation, and desired time-to-market. These new tools must be incorporated into a new approach to NPD based on the Advanced Product and Quality Planning methodology.

  14. Low-Cost Resonant Cavity Raman Gas Probe for Multi-Gas Detection

    Science.gov (United States)

    Thorstensen, J.; Haugholt, K. H.; Ferber, A.; Bakke, K. A. H.; Tschudi, J.

    2014-12-01

    Raman based gas sensing can be attractive in several industrial applications, due to its multi-gas sensing capabilities and its ability to detect O_2 and N_2. In this article, we have built a Raman gas probe, based on low-cost components, which has shown an estimated detection limit of 0.5 % for 30 second measurements of N_2 and O_2. While this detection limit is higher than that of commercially available equipment, our estimated component cost is approximately one tenth of the price of commercially available equipment. The use of a resonant Fabry-Pérot cavity increases the scattered signal, and hence the sensitivity, by a factor of 50. The cavity is kept in resonance using a piezo-actuated mirror and a photodiode in a feedback loop. The system described in this article was made with minimum-cost components to demonstrate the low-cost principle. However, it is possible to decrease the detection limit using a higher-powered (but still low-cost) laser and improving the collection optics. By applying these improvements, the detection limit and estimated measurement precision will be sufficient for e.g. the monitoring of input gases in combustion processes, such as e.g. (bio-)gas power plants. In these processes, knowledge about gas compositions with 0.1 % (absolute) precision can help regulate and optimize process conditions. The system has the potential to provide a low-cost, industrial Raman sensor that is optimized for specific gas-detection applications.

  15. Pathology economic model tool: a novel approach to workflow and budget cost analysis in an anatomic pathology laboratory.

    Science.gov (United States)

    Muirhead, David; Aoun, Patricia; Powell, Michael; Juncker, Flemming; Mollerup, Jens

    2010-08-01

    The need for higher efficiency, maximum quality, and faster turnaround time is a continuous focus for anatomic pathology laboratories and drives changes in work scheduling, instrumentation, and management control systems. To determine the costs of generating routine, special, and immunohistochemical microscopic slides in a large, academic anatomic pathology laboratory using a top-down approach. The Pathology Economic Model Tool was used to analyze workflow processes at The Nebraska Medical Center's anatomic pathology laboratory. Data from the analysis were used to generate complete cost estimates, which included not only materials, consumables, and instrumentation but also specific labor and overhead components for each of the laboratory's subareas. The cost data generated by the Pathology Economic Model Tool were compared with the cost estimates generated using relative value units. Despite the use of automated systems for different processes, the workflow in the laboratory was found to be relatively labor intensive. The effect of labor and overhead on per-slide costs was significantly underestimated by traditional relative-value unit calculations when compared with the Pathology Economic Model Tool. Specific workflow defects with significant contributions to the cost per slide were identified. The cost of providing routine, special, and immunohistochemical slides may be significantly underestimated by traditional methods that rely on relative value units. Furthermore, a comprehensive analysis may identify specific workflow processes requiring improvement.

  16. Satellite-aided survey sampling and implementation in low- and middle-income contexts: a low-cost/low-tech alternative.

    Science.gov (United States)

    Haenssgen, Marco J

    2015-01-01

    The increasing availability of online maps, satellite imagery, and digital technology can ease common constraints of survey sampling in low- and middle-income countries. However, existing approaches require specialised software and user skills, professional GPS equipment, and/or commercial data sources; they tend to neglect spatial sampling considerations when using satellite maps; and they continue to face implementation challenges analogous to conventional survey implementation methods. This paper presents an alternative way of utilising satellite maps and digital aides that aims to address these challenges. The case studies of two rural household surveys in Rajasthan (India) and Gansu (China) compare conventional survey sampling and implementation techniques with the use of online map services such as Google, Bing, and HERE maps. Modern yet basic digital technology can be integrated into the processes of preparing, implementing, and monitoring a rural household survey. Satellite-aided systematic random sampling enhanced the spatial representativeness of the village samples and entailed savings of approximately £4000 compared to conventional household listing, while reducing the duration of the main survey by at least 25 %. This low-cost/low-tech satellite-aided survey sampling approach can be useful for student researchers and resource-constrained research projects operating in low- and middle-income contexts with high survey implementation costs. While achieving transparent and efficient survey implementation at low costs, researchers aiming to adopt a similar process should be aware of the locational, technical, and logistical requirements as well as the methodological challenges of this strategy.

  17. Cultural Heritage Recording Utilising Low-Cost Closerange Photogrammetry

    Directory of Open Access Journals (Sweden)

    Melanie Kirchhöfer

    2011-12-01

    Full Text Available Cultural heritage is under a constant threat of damage or even destruction and comprehensive and accurate recording is necessary to attenuate the risk of losing heritage or serve as basis for reconstruction. Cost effective and easy to use methods are required to record cultural heritage, particularly during a world recession, and close-range photogrammetry has proven potential in this area. Off-the-shelf digital cameras can be used to rapidly acquire data at low cost, allowing non-experts to become involved. Exterior orientation of the camera during exposure ideally needs to be established for every image, traditionally requiring known coordinated target points. Establishing these points is time consuming and costly and using targets can be often undesirable on sensitive sites. MEMS-based sensors can assist in overcoming this problem by providing small-size and low-cost means to directly determine exterior orientation for close-range photogrammetry. This paper describes development of an image-based recording system, comprising an off-the-shelf digital SLR camera, a MEMS-based 3D orientation sensor and a GPS antenna. All system components were assembled in a compact and rigid frame that allows calibration of rotational and positional offsets between the components. The project involves collaboration between English Heritage and Loughborough University and the intention is to assess the system’s achievable accuracy and practicability in a heritage recording environment. Tests were conducted at Loughborough University and a case study at St. Catherine’s Oratory on the Isle of Wight, UK. These demonstrate that the data recorded by the system can indeed meet the accuracy requirements for heritage recording at medium accuracy (1-4cm, with either a single or even no control points. As the recording system has been configured with a focus on low-cost and easy-to-use components, it is believed to be suitable for heritage recording by non

  18. Innovative approach for low-cost quick-access small payload missions

    Science.gov (United States)

    Friis, Jan W., Jr.

    2000-11-01

    A significant part of the burgeoning commercial space industry is placing an unprecedented number of satellites into low earth orbit for a variety of new applications and services. By some estimates the commercial space industry now exceeds that of government space activities. Yet the two markets remain largely separate, with each deploying dedicated satellites and infrastructure for their respective missions. One commercial space firm, Final Analysis, has created a new program wherein either government, scientific or new technology payloads can be integrated on a commercial spacecraft on commercial satellites for a variety of mission scenarios at a fraction of the cost of a dedicated mission. NASA has recognized the advantage of this approach, and has awarded the Quick Ride program to provide frequent, low cost flight opportunities for small independent payloads aboard the Final Analysis constellation, and investigators are rapidly developing science programs that conform to the proposed payload accommodations envelope. Missions that were not feasible using dedicated launches are now receiving approval under the lower cost Quick Ride approach. Final Analysis has dedicated ten out of its thirty-eight satellites in support of the Quick Ride efforts. The benefit of this type of space access extend beyond NASA science programs. Commercial space firms can now gain valuable flight heritage for new technology and satellite product offerings. Further, emerging international space programs can now place a payload in orbit enabling the country to allocate its resources against the payload and mission requirements rather htan increased launch costs of a dedicated spacecraft. Finally, the low cost nature provides University-based research educational opportunities previously out of the reach of most space-related budgets. This paper will describe the motivation, benefits, technical features, and program costs of the Final Analysis secondary payload program. Payloads can be

  19. Sequential Low Cost Interventions Double Hand Hygiene Rates ...

    African Journals Online (AJOL)

    Sequential Low Cost Interventions Double Hand Hygiene Rates Among Medical Teams in a Resource Limited Setting. Results of a Hand Hygiene Quality Improvement Project Conducted At University Teaching Hospital of Kigali (Chuk), Kigali, Rwanda.

  20. Low-cost, locally available shelters in Pakistan

    Directory of Open Access Journals (Sweden)

    Ammarah Mubarak

    2017-06-01

    Full Text Available Flooding in 2010 affected 18 million people in Pakistan. With declining donor funds and flooding again in 2011 and 2012, the humanitarian community required low-cost solutions that could be scaled up to meet both the immediate and the transitional needs of large populations in differing geographical areas.

  1. A high-performance, low-cost, leading edge discriminator

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics; Volume 65; Issue 2 ... commercial discriminators. A low-cost discriminator is an essential requirement of the GRAPES-3 experiment where a large number of discriminator channels are used.

  2. Results from evaluations of models and cost-effectiveness tools to support introduction decisions for new vaccines need critical appraisal

    Directory of Open Access Journals (Sweden)

    Moorthy Vasee

    2011-05-01

    Full Text Available Abstract The World Health Organization (WHO recommends that the cost-effectiveness (CE of introducing new vaccines be considered before such a programme is implemented. However, in low- and middle-income countries (LMICs, it is often challenging to perform and interpret the results of model-based economic appraisals of vaccines that benefit from locally relevant data. As a result, WHO embarked on a series of consultations to assess economic analytical tools to support vaccine introduction decisions for pneumococcal, rotavirus and human papillomavirus vaccines. The objectives of these assessments are to provide decision makers with a menu of existing CE tools for vaccines and their characteristics rather than to endorse the use of a single tool. The outcome will provide policy makers in LMICs with information about the feasibility of applying these models to inform their own decision making. We argue that if models and CE analyses are used to inform decisions, they ought to be critically appraised beforehand, including a transparent evaluation of their structure, assumptions and data sources (in isolation or in comparison to similar tools, so that decision makers can use them while being fully aware of their robustness and limitations.

  3. Quantifying the properties of low-cost powder metallurgy titanium alloys

    International Nuclear Information System (INIS)

    Bolzoni, L.; Ruiz-Navas, E.M.; Gordo, E.

    2017-01-01

    The extensive industrial employment of titanium is hindered by its high production costs where reduction of these costs can be achieved using cheap alloying elements and appropriate alternative processing techniques. In this work the feasibility of the production of low-cost titanium alloys is addressed by adding steel to pure titanium and processing the alloys by powder metallurgy. In particular, a spherical 4140 LCH steel powder commonly used in metal injection moulding is blended with irregular hydride-dehydride Ti. The new low-cost alloys are cold uniaxially pressed and sintered under high vacuum and show comparable properties to other wrought-equivalent and powder metallurgy titanium alloys. Differential thermal analysis and X-ray diffraction analyses confirm that Ti can tolerate the employment of iron as primary alloying element without forming detrimental TiFe-based intermetallic phases. Thus, the newly designed α+β alloys could be used for cheaper non-critical components.

  4. Quantifying the properties of low-cost powder metallurgy titanium alloys

    Energy Technology Data Exchange (ETDEWEB)

    Bolzoni, L., E-mail: bolzoni.leandro@gmail.com [WaiCAM (Waikato Centre for Advanced Materials), The University of Waikato, Private Bag 3105, 3240 Hamilton (New Zealand); Ruiz-Navas, E.M.; Gordo, E. [Department of Materials Science and Engineering, University Carlos III of Madrid, Avda. de la Universidad, 30, 28911 Leganés, Madrid (Spain)

    2017-02-27

    The extensive industrial employment of titanium is hindered by its high production costs where reduction of these costs can be achieved using cheap alloying elements and appropriate alternative processing techniques. In this work the feasibility of the production of low-cost titanium alloys is addressed by adding steel to pure titanium and processing the alloys by powder metallurgy. In particular, a spherical 4140 LCH steel powder commonly used in metal injection moulding is blended with irregular hydride-dehydride Ti. The new low-cost alloys are cold uniaxially pressed and sintered under high vacuum and show comparable properties to other wrought-equivalent and powder metallurgy titanium alloys. Differential thermal analysis and X-ray diffraction analyses confirm that Ti can tolerate the employment of iron as primary alloying element without forming detrimental TiFe-based intermetallic phases. Thus, the newly designed α+β alloys could be used for cheaper non-critical components.

  5. development of low-cost educational materials for chemistry

    African Journals Online (AJOL)

    unesco

    development of low-cost Chemistry materials from locally available materials. It finally lists the ... According to the World Bank discussion paper (3) large investments have been made to improve the .... official language in Ethiopia) and English.

  6. Commercial Motion Sensor Based Low-Cost and Convenient Interactive Treadmill

    Directory of Open Access Journals (Sweden)

    Jonghyun Kim

    2015-09-01

    Full Text Available Interactive treadmills were developed to improve the simulation of overground walking when compared to conventional treadmills. However, currently available interactive treadmills are expensive and inconvenient, which limits their use. We propose a low-cost and convenient version of the interactive treadmill that does not require expensive equipment and a complicated setup. As a substitute for high-cost sensors, such as motion capture systems, a low-cost motion sensor was used to recognize the subject’s intention for speed changing. Moreover, the sensor enables the subject to make a convenient and safe stop using gesture recognition. For further cost reduction, the novel interactive treadmill was based on an inexpensive treadmill platform and a novel high-level speed control scheme was applied to maximize performance for simulating overground walking. Pilot tests with ten healthy subjects were conducted and results demonstrated that the proposed treadmill achieves similar performance to a typical, costly, interactive treadmill that contains a motion capture system and an instrumented treadmill, while providing a convenient and safe method for stopping.

  7. State estimation and control for low-cost unmanned aerial vehicles

    CERN Document Server

    Hajiyev, Chingiz; Yenal Vural, Sıtkı

    2015-01-01

    This book discusses state estimation and control procedures for a low-cost unmanned aerial vehicle (UAV). The authors consider the use of robust adaptive Kalman filter algorithms and demonstrate their advantages over the optimal Kalman filter in the context of the difficult and varied environments in which UAVs may be employed. Fault detection and isolation (FDI) and data fusion for UAV air-data systems are also investigated, and control algorithms, including the classical, optimal, and fuzzy controllers, are given for the UAV. The performance of different control methods is investigated and the results compared. State Estimation and Control of Low-Cost Unmanned Aerial Vehicles covers all the important issues for designing a guidance, navigation and control (GNC) system of a low-cost UAV. It proposes significant new approaches that can be exploited by GNC system designers in the future and also reviews the current literature. The state estimation, control and FDI methods are illustrated by examples and MATLAB...

  8. Multi-robot system using low-cost infrared sensors

    Directory of Open Access Journals (Sweden)

    Anubhav Kakkar

    2013-03-01

    Full Text Available This paper presents a proposed set of the novel technique, methods, and algorithm for simultaneous path planning, area exploration, area retrieval, obstacle avoidance, object detection, and object retrieval   autonomously by a multi-robot system. The proposed methods and algorithms are built considering the use of low cost infrared sensors with the ultimate function of efficiently exploring the given unknown area and simultaneously identifying desired objects by analyzing the physical characteristics of several of the objects that come across during exploration. In this paper, we have explained the scenario by building a coordinative multi-robot system consisting of two autonomously operated robots equipped with low-cost and low-range infrared sensors to perform the assigned task by analyzing some of the sudden changes in their environment. Along with identifying and retrieving the desired object, the proposed methodology also provide an inclusive analysis of the area being explored. The novelties presented in the paper may significantly provide a cost-effective solution to the problem of area exploration and finding a known object in an unknown environment by demonstrating an innovative approach of using the infrared sensors instead of high cost long range sensors and cameras. Additionally, the methodology provides a speedy and uncomplicated method of traversing a complicated arena while performing all the necessary and inter-related tasks of avoiding the obstacles, analyzing the area as well as objects, and reconstructing the area using all these information collected and interpreted for an unknown environment. The methods and algorithms proposed are simulated over a complex arena to depict the operations and manually tested over a physical environment which provided 78% correct results with respect to various complex parameters set randomly.

  9. Low-cost near-infrared imaging device for inspection of historical manuscripts

    International Nuclear Information System (INIS)

    Mohd Ashhar Khalid

    2004-01-01

    Near-infrared (NIR) or sometimes called black light is a waveform beyond visible light and it is not detectable by human eyes. However electronic sensors such as the type used in digital cameras are able to detect signals in the infrared band. To avoid distortion in the pictures obtained near-infrared is blocked by optical filters inserted in digital cameras. By carrying out minor modification allowing near-infrared signal to be imaged while blocking the visible signal, the camera is turned into a low-cost NIR imaging instrument. NIR imaging can be a useful tool in historical manuscript study or restoration. A few applications have been successfully demonstrated in laboratory experiment using the instrument available in MINT. However, due to unavailability of historical items, easily available texts and paintings are used in the demonstrations. This paper reports achievements of early work on the application of digital camera in the detection of damaged prints or writings. (Author)

  10. The Vertical-Tube Solar Collector: A Low-Cost Design Suitable for Temperate High-Latitude Locations

    Directory of Open Access Journals (Sweden)

    Luis Juanicó

    2014-01-01

    Full Text Available A new low-cost solar collector based on thick (4.5′′ vertical tubes related to the previous design based on long 1.5′′ plastic hoses connected directly between water-grid supply and consumption is presented. This novel design could noticeably improve its performance for temperate locations mid and high latitudes, as was demonstrated by dynamic thermal modeling. This tool has been useful for understanding the particular characteristics of this kind of water-pond collector and besides, for noticeably improving its performance by optimizing its parameters, like tube diameter and number of glazing layers. By this way, the optimized design could fully satisfy the household demand up to midnight along the whole year for Buenos Aires (35°S and during summers (remaining as a useful preheater for the whole year for Ushuaia (55°S. Besides, its high simplicity makes it available for user’s own construction, costing down 50 dollars for a single-family unit.

  11. Low-cost universal stereoscopic virtual reality interfaces

    Science.gov (United States)

    Starks, Michael R.

    1993-09-01

    Low cost stereoscopic virtual reality hardware interfacing with nearly any computer and stereoscopic software running on any PC is described. Both are user configurable for serial or parallel ports. Stereo modeling, rendering, and interaction via gloves or 6D mice are provided. Low cost LCD Visors and external interfaces represent a breakthrough in convenience and price/performance. A complete system with software, Visor, interface and Power Glove is under $DOL500. StereoDrivers will interface with any system giving video sync (e.g., G of RGB). PC3D will access any standard serial port, while PCVR works with serial or parallel ports and glove devices. Model RF Visors detect magnetic fields and require no connection to the system. PGSI is a microprocessor control for the Power Glove and Visors. All interfaces will operate to 120 Hz with Model G Visors. The SpaceStations are demultiplexing, field doubling devices which convert field sequential video or graphics for stereo display with dual video projection or dual LCD SpaceHelmets.

  12. Low-cost metamaterial-on-paper chemical sensor.

    Science.gov (United States)

    Sadeqi, Aydin; Nejad, Hojatollah Rezaei; Sonkusale, Sameer

    2017-07-10

    We present a disposable low cost paper-based metamaterial for sensing liquids based on their dielectric properties. The sensor is based on resonance shift due to the change in the effective capacitance of each resonator in the metamaterial array. Key novelty in the design is the implementation of metamaterial on low cost and ubiquitous paper substrate. This metamaterial-on-paper sensor is fabricated in a totally cleanroom-free process using wax printing and screen printing. Wax patterning of paper enables creation of microfluidic channels such that liquid analytes can be delivered to each metamaterial unit cell for sensing. Screen printing is used to implement disc shaped resonator unit cells. We demonstrate sensing of liquids: Oil, methanol, glycerol and water each showing an average resonance frequency shift of 1.12 (9.6%), 4.12 (35.4%), 8.76 (75.3%) and 11.63 GHz (100%) around the center frequency of around 94 GHz respectively. Being label-free, this approach can be expanded to sense other liquids based on their dielectric constants.

  13. Low-Cost Phase Change Material for Building Envelopes

    Energy Technology Data Exchange (ETDEWEB)

    Abhari, Ramin [Renewable Energy Group

    2015-08-06

    A low-cost PCM process consisting of conversion of fats and oils to PCM-range paraffins, and subsequent “encapsulation” of the paraffin using conventional plastic compounding/pelletizing equipment was demonstrated. The PCM pellets produced were field-tested in a building envelope application. This involved combining the PCM pellets with cellulose insulation, whereby 33% reduction in peak heat flux and 12% reduction in heat gain was observed (average summertime performance). The selling price of the PCM pellets produced according to this low-cost process is expected to be in the $1.50-$3.00/lb range, compared to current encapsulated PCM price of about $7.00/lb. Whole-building simulations using corresponding PCM thermal analysis data suggest a payback time of 8 to 16 years (at current energy prices) for an attic insulation retrofit project in the Phoenix climate area.

  14. Low-cost digital GPS receiver with software carrier detection

    Science.gov (United States)

    Wolf, M. H.

    1988-08-01

    The satellite navigation system global positioning system (GPS) will play a major role in the field of navigation. It will be able to compete with all previously existing radio navigation systems. Low-cost receivers will be built for a number of civilian users, such as general aviation, sea and land navigation. To permit production at low cost for the civil market, a new technique for a C/A (course and acquisition) code receiver has been developed. All the signal detecting and processing is carried out with the digital signal processing software in a Texas Instruments TMS 320C10. The advantage of this method is that complex functions can be effected in a computer program instead of in analog or digital circuits. This reduces the costs of the parts used in the receiver and also avoids calibration. Taken together, these two features greatly reduce the price of a navigation set. This paper discusses the underlying principles leading to this new receiver.

  15. End-user perspective of low-cost sensors for outdoor air pollution monitoring.

    Science.gov (United States)

    Rai, Aakash C; Kumar, Prashant; Pilla, Francesco; Skouloudis, Andreas N; Di Sabatino, Silvana; Ratti, Carlo; Yasar, Ansar; Rickerby, David

    2017-12-31

    Low-cost sensor technology can potentially revolutionise the area of air pollution monitoring by providing high-density spatiotemporal pollution data. Such data can be utilised for supplementing traditional pollution monitoring, improving exposure estimates, and raising community awareness about air pollution. However, data quality remains a major concern that hinders the widespread adoption of low-cost sensor technology. Unreliable data may mislead unsuspecting users and potentially lead to alarming consequences such as reporting acceptable air pollutant levels when they are above the limits deemed safe for human health. This article provides scientific guidance to the end-users for effectively deploying low-cost sensors for monitoring air pollution and people's exposure, while ensuring reasonable data quality. We review the performance characteristics of several low-cost particle and gas monitoring sensors and provide recommendations to end-users for making proper sensor selection by summarizing the capabilities and limitations of such sensors. The challenges, best practices, and future outlook for effectively deploying low-cost sensors, and maintaining data quality are also discussed. For data quality assurance, a two-stage sensor calibration process is recommended, which includes laboratory calibration under controlled conditions by the manufacturer supplemented with routine calibration checks performed by the end-user under final deployment conditions. For large sensor networks where routine calibration checks are impractical, statistical techniques for data quality assurance should be utilised. Further advancements and adoption of sophisticated mathematical and statistical techniques for sensor calibration, fault detection, and data quality assurance can indeed help to realise the promised benefits of a low-cost air pollution sensor network. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. A Vehicle Steering Recognition System Based on Low-Cost Smartphone Sensors

    Directory of Open Access Journals (Sweden)

    Xinhua Liu

    2017-03-01

    Full Text Available Recognizing how a vehicle is steered and then alerting drivers in real time is of utmost importance to the vehicle and driver’s safety, since fatal accidents are often caused by dangerous vehicle maneuvers, such as rapid turns, fast lane-changes, etc. Existing solutions using video or in-vehicle sensors have been employed to identify dangerous vehicle maneuvers, but these methods are subject to the effects of the environmental elements or the hardware is very costly. In the mobile computing era, smartphones have become key tools to develop innovative mobile context-aware systems. In this paper, we present a recognition system for dangerous vehicle steering based on the low-cost sensors found in a smartphone: i.e., the gyroscope and the accelerometer. To identify vehicle steering maneuvers, we focus on the vehicle’s angular velocity, which is characterized by gyroscope data from a smartphone mounted in the vehicle. Three steering maneuvers including turns, lane-changes and U-turns are defined, and a vehicle angular velocity matching algorithm based on Fast Dynamic Time Warping (FastDTW is adopted to recognize the vehicle steering. The results of extensive experiments show that the average accuracy rate of the presented recognition reaches 95%, which implies that the proposed smartphone-based method is suitable for recognizing dangerous vehicle steering maneuvers.

  17. Smartfactory, a modular, low cost productivity monitoring system

    CSIR Research Space (South Africa)

    Bosscha, PA

    2010-07-01

    Full Text Available lack of objectivity and plain incorrect data entries. In aid of the SMMEs the Smartfactory system offers a low-cost modular monitoring solution capable of implementation in a step by step fashion with little training required in installation...

  18. GCP 1.0: A Tool for Cost Management in Micro and Small Textile Manufacturing Companies in Bucaramanga

    Directory of Open Access Journals (Sweden)

    Ofelia Gómez Niño

    2015-11-01

    Full Text Available This article presents the results of a diagnostic study in which 52 textile manufacturing companies were observed in Bucaramanga to characterize the needs of these productive units. Based on the results, three strategic options were formulated to improve performance: a To consolidate the productive system by tools that facilitate production processes, b to strengthen cost structure by designing systems and tools; and c to share technological initiatives, knowledge and experience to improve resource management. From this perspective, the second phase of the research was oriented to develop the software GCP 1.0 for micro and small companies of children’s confection in Bucaramanga, a production cost information system that would facilitate cost management and the fixation of sale prices.

  19. Inkjet-Printed Electrodes on A4 Paper Substrates for Low-Cost, Disposable, and Flexible Asymmetric Supercapacitors.

    Science.gov (United States)

    Sundriyal, Poonam; Bhattacharya, Shantanu

    2017-11-08

    Printed electronics is widely gaining much attention for compact and high-performance energy-storage devices because of the advancement of flexible electronics. The development of a low-cost current collector, selection, and utilization of the proper material deposition tool and improvement of the device energy density are major challenges for the existing flexible supercapacitors. In this paper, we have reported an inkjet-printed solid-state asymmetric supercapacitor on commercial A4 paper using a low-cost desktop printer (EPSON L130). The physical properties of all inks have been carefully optimized so that the developed inks are within the printable range, i.e., Fromm number of 4 electrode, and another such structure is printed with activated carbon ink to form a negative electrode. A combination of both of these electrodes is outlaid by fabricating an asymmetric supercapacitor. The assembled asymmetric supercapacitor with poly(vinyl alcohol) (PVA)-LiCl gel electrolyte shows a stable potential window of 0-2.0 V and exhibits outstanding flexibility, good cyclic stability, high rate capability, and high energy density. The fabricated paper-substrate-based flexible asymmetric supercapacitor also displays an excellent electrochemical performances, e.g., a maximum areal capacitance of 1.586 F/cm 2 (1023 F/g) at a current density of 4 mA/cm 2 , highest energy density of 22 mWh/cm 3 at a power density of 0.099 W/cm 3 , a capacity retention of 89.6% even after 9000 charge-discharge cycles, and a low charge-transfer resistance of 2.3 Ω. So, utilization of inkjet printing for the development of paper-based flexible electronics has a strong potential for embedding into the next generation low-cost, compact, and wearable energy-storage devices and other printed electronic applications.

  20. Low cost sic coated erosion resistant graphite

    International Nuclear Information System (INIS)

    Zafar, M.F.; Nicholls, J.R.

    2007-01-01

    The development of materials with unique and improved properties using low cost processes is essential to increase performance and reduce cost of the solid rocket motors. Specifically advancements are needed for boost phase nozzle. As these motors operate at very high pressure and temperatures, the nozzle must survive high thermal stresses with minimal erosion to maintain performance. Currently three material choices are being exploited; which are refractory metals, graphite and carbon-carbon composites. Of these three materials graphite is the most attractive choice because of its low cost, light weight, and easy forming. However graphite is prone to erosion, both chemical and mechanical, which may affect the ballistic conditions and mechanical properties of the nozzle. To minimize this erosion high density graphite is usually preferred; which is again very expensive. Another technique used to minimize the erosion is Pyrolytic Graphite (PG) coating inside the nozzle. However PG coating is prone to cracking and spallation along with very cumbersome deposition process. Another possible methodology to avoid this erosion is to convert the inside surface of the rocket nozzle to Silicon Carbide (SiC), which is very erosion resistant and have much better thermal stability compared to graphite and even PG. Due to its functionally gradient nature such a layer will be very adherent and resistant to spallation. The current research is focused on synthesizing, characterizing and oxidation testing of such a converted SiC layer on commercial grade graphite. (author)

  1. Palliative and low cost radiotherapy in developing countries

    International Nuclear Information System (INIS)

    Allen, Barry; Hussein, S.M.A.

    2011-01-01

    Full text: The International Agency for Research on Cancer predicts that cancer incidence in developing countries will increase dramatically in the first two decades of this millennium. Already some 80% of cancer patients in developing countries present with incurable disease. In many cases pain is a severe problem and palliation is needed to improve quality of life as well as extending survival. This paper will consider the physical and clinical aspects of palliative radiotherapy (PRT), choice of radiation modality, alternative approaches to imaging and therapy and cost-benefit considerations. The potential benefits of a dedicated palliative care centre include lower cost and therefore more centres, enabling more patients access to regional palliative care. Simple curative treatments could also be managed. Co60 radiotherapy has important advantages in developing countries, because of the higher initial cost of a linear accelerator, as well as the need for reliable power supply and the level of skill required by linac technicians and physicists. The beam characteristics of both Co60 units and low energy linacs are compared and both are found to be acceptable for palliation. The role of palliative and low cost radiotherapy in Bangladesh is reviewed. The concept of telemedicine is also discussed, using mobile phones and internet communication to allow rural clinics to receive support from specialists based in the cities, to send images for remote diagnosis and remote dose planning for radiotherapy.

  2. How Europe's Low-Cost Carriers Sidestepped Traditional Carriers' Competitive Advantages

    DEFF Research Database (Denmark)

    Hvass, Kristian Anders

    -cost airlines were more successful and had a greater initial impact in their early years than their U.S. compatriots. This paper will attempt to highlight some of the differences between the two markets and explain why European low-cost airlines had more advantages following their market deregulation...

  3. Hydrocarbons - In the era of low-cost oil

    International Nuclear Information System (INIS)

    Dupin, Ludovic; Delamarche, Myrtille; Cognasse, Olivier; De Jaegher, Thibaut; Fleitour, Gaelle

    2015-01-01

    A set of articles addresses the current context of low cost oil and steep drop in oil prices. Graphs illustrate the evolution of oil prices, of supply and demand, of exploitation costs. This drop is partly due to the high level of production in Russia, Iraq and USA. This context results in drastic reductions of investments by companies involved in the oil sector, and therefore in job reduction, and in reduction of service costs. These reductions impact actors of the seismic analysis sector. Other consequences are more positive for consumers and refiners, and a trend towards diversification and consolidation for operators. The chairman of Technip answers some questions on Technip activities, situation and strategy. The case of the petrochemical sector is also addressed

  4. Prototyping low-cost and flexible vehicle diagnostic systems

    Directory of Open Access Journals (Sweden)

    Marisol GARCÍA-VALLS

    2016-12-01

    Full Text Available Diagnostic systems are software and hardware-based equipment that interoperate with an external monitored system. Traditionally, they have been expensive equipment running test algorithms to monitor physical properties of, e.g., vehicles, or civil infrastructure equipment, among others. As computer hardware is increasingly powerful (whereas its cost and size is decreasing and communication software becomes easier to program and more run-time efficient, new scenarios are enabled that yield to lower cost monitoring solutions. This paper presents a low cost approach towards the development of a diagnostic systems relying on a modular component-based approach and running on a resource limited embedded computer. Results on a prototype implementation are shown that validate the presented design, its flexibility, performance, and communication latency.

  5. Air Muscle Actuated Low Cost Humanoid Hand

    Directory of Open Access Journals (Sweden)

    Peter Scarfe

    2008-11-01

    Full Text Available The control of humanoid robot hands has historically been expensive due to the cost of precision actuators. This paper presents the design and implementation of a low-cost air muscle actuated humanoid hand developed at Curtin University of Technology. This hand offers 10 individually controllable degrees of freedom ranging from the elbow to the fingers, with overall control handled through a computer GUI. The hand is actuated through 20 McKibben-style air muscles, each supplied by a pneumatic pressure-balancing valve that allows for proportional control to be achieved with simple and inexpensive components. The hand was successfully able to perform a number of human-equivalent tasks, such as grasping and relocating objects.

  6. Air Muscle Actuated Low Cost Humanoid Hand

    Directory of Open Access Journals (Sweden)

    Peter Scarfe

    2006-06-01

    Full Text Available The control of humanoid robot hands has historically been expensive due to the cost of precision actuators. This paper presents the design and implementation of a low-cost air muscle actuated humanoid hand developed at Curtin University of Technology. This hand offers 10 individually controllable degrees of freedom ranging from the elbow to the fingers, with overall control handled through a computer GUI. The hand is actuated through 20 McKibben-style air muscles, each supplied by a pneumatic pressure-balancing valve that allows for proportional control to be achieved with simple and inexpensive components. The hand was successfully able to perform a number of human-equivalent tasks, such as grasping and relocating objects.

  7. Clean utilization of low-rank coals for low-cost power generation

    International Nuclear Information System (INIS)

    Sondreal, E.A.

    1992-01-01

    Despite the unique utilization problems of low-rank coals, the ten US steam electric plants having the lowest operating cost in 1990 were all fueled on either lignite or subbituminous coal. Ash deposition problems, which have been a major barrier to sustaining high load on US boilers burning high-sodium low-rank coals, have been substantially reduced by improvements in coal selection, boiler design, on-line cleaning, operating conditions, and additives. Advantages of low-rank coals in advanced systems are their noncaking behavior when heated, their high reactivity allowing more complete reaction at lower temperatures, and the low sulfur content of selected deposits. The principal barrier issues are the high-temperature behavior of ash and volatile alkali derived from the coal-bound sodium found in some low-rank coals. Successful upgrading of low-rank coals requires that the product be both stable and suitable for end use in conventional and advanced systems. Coal-water fuel produced by hydrothermal processing of high-moisture low-rank coal meets these criteria, whereas most dry products from drying or carbonizing in hot gas tend to create dust and spontaneous ignition problems unless coated, agglomerated, briquetted, or afforded special handling

  8. Alternative ceramic circuit constructions for low cost, high reliability applications

    International Nuclear Information System (INIS)

    Modes, Ch.; O'Neil, M.

    1997-01-01

    The growth in the use of hybrid circuit technology has recently been challenged by recent advances in low cost laminate technology, as well as the continued integration of functions into IC's. Size reduction of hybrid 'packages' has turned out to be a means to extend the useful life of this technology. The suppliers of thick film materials technology have responded to this challenge by developing a number of technology options to reduce circuit size, increase density, and reduce overall cost, while maintaining or increasing reliability. This paper provides an overview of the processes that have been developed, and, in many cases are used widely to produce low cost, reliable microcircuits. Comparisons of each of these circuit fabrication processes are made with a discussion of advantages and disadvantages of each technology. (author)

  9. Low-cost Volumetric Ultrasound by Augmentation of 2D Systems: Design and Prototype.

    Science.gov (United States)

    Herickhoff, Carl D; Morgan, Matthew R; Broder, Joshua S; Dahl, Jeremy J

    2018-01-01

    Conventional two-dimensional (2D) ultrasound imaging is a powerful diagnostic tool in the hands of an experienced user, yet 2D ultrasound remains clinically underutilized and inherently incomplete, with output being very operator dependent. Volumetric ultrasound systems can more fully capture a three-dimensional (3D) region of interest, but current 3D systems require specialized transducers, are prohibitively expensive for many clinical departments, and do not register image orientation with respect to the patient; these systems are designed to provide improved workflow rather than operator independence. This work investigates whether it is possible to add volumetric 3D imaging capability to existing 2D ultrasound systems at minimal cost, providing a practical means of reducing operator dependence in ultrasound. In this paper, we present a low-cost method to make 2D ultrasound systems capable of quality volumetric image acquisition: we present the general system design and image acquisition method, including the use of a probe-mounted orientation sensor, a simple probe fixture prototype, and an offline volume reconstruction technique. We demonstrate initial results of the method, implemented using a Verasonics Vantage research scanner.

  10. Algolcam: Low Cost Sky Scanning with Modern Technology

    Science.gov (United States)

    Connors, Martin; Bolton, Dempsey; Doktor, Ian

    2016-01-01

    Low cost DSLR cameras running under computer control offer good sensitivity, high resolution, small size, and the convenience of digital image handling. Recent developments in small single board computers have pushed the performance to cost and size ratio to unprecedented values, with the further advantage of very low power consumption. Yet a third technological development is motor control electronics which is easily integrated with the computer to make an automated mount, which in our case is custom built, but with similar mounts available commercially. Testing of such a system under a clear plastic dome at our auroral observatory was so successful that we have developed a weatherproof housing allowing use during the long, cold, and clear winter nights at northerly latitudes in Canada. The main advantage of this housing should be improved image quality as compared to operation through clear plastic. We have improved the driving software to include the ability to self-calibrate pointing through the web API of astrometry.net, and data can be reduced automatically through command line use of the Muniwin program. The mount offers slew in declination and RA, and tracking at sidereal or other rates in RA. Our previous tests with a Nikon D5100 with standard lenses in the focal length range 50-200 mm, operating at f/4 to f/5, allowed detection of 12th magnitude stars with 30 second exposure under very dark skies. At 85 mm focal length, a field of 15° by 10° is imaged with 4928 by 3264 color pixels, and we have adopted an 85 mm fixed focal length f/1.4 lens (as used by Project Panoptes), which we expect will give a limited magnitude approaching 15. With a large field of view, deep limiting magnitude, low cost, and ease of construction and use, we feel that the Algolcam offers great possibilities in monitoring and finding changes in the sky. We have already applied it to variable star light curves, and with a suitable pipeline for detection of moving or varying objects

  11. Development of low-cost high-performance multispectral camera system at Banpil

    Science.gov (United States)

    Oduor, Patrick; Mizuno, Genki; Olah, Robert; Dutta, Achyut K.

    2014-05-01

    Banpil Photonics (Banpil) has developed a low-cost high-performance multispectral camera system for Visible to Short- Wave Infrared (VIS-SWIR) imaging for the most demanding high-sensitivity and high-speed military, commercial and industrial applications. The 640x512 pixel InGaAs uncooled camera system is designed to provide a compact, smallform factor to within a cubic inch, high sensitivity needing less than 100 electrons, high dynamic range exceeding 190 dB, high-frame rates greater than 1000 frames per second (FPS) at full resolution, and low power consumption below 1W. This is practically all the feature benefits highly desirable in military imaging applications to expand deployment to every warfighter, while also maintaining a low-cost structure demanded for scaling into commercial markets. This paper describes Banpil's development of the camera system including the features of the image sensor with an innovation integrating advanced digital electronics functionality, which has made the confluence of high-performance capabilities on the same imaging platform practical at low cost. It discusses the strategies employed including innovations of the key components (e.g. focal plane array (FPA) and Read-Out Integrated Circuitry (ROIC)) within our control while maintaining a fabless model, and strategic collaboration with partners to attain additional cost reductions on optics, electronics, and packaging. We highlight the challenges and potential opportunities for further cost reductions to achieve a goal of a sub-$1000 uncooled high-performance camera system. Finally, a brief overview of emerging military, commercial and industrial applications that will benefit from this high performance imaging system and their forecast cost structure is presented.

  12. Draw your assay: Fabrication of low-cost paper-based diagnostic and multi-well test zones by drawing on a paper.

    Science.gov (United States)

    Oyola-Reynoso, Stephanie; Heim, Andrew P; Halbertsma-Black, Julian; Zhao, C; Tevis, Ian D; Çınar, Simge; Cademartiri, Rebecca; Liu, Xinyu; Bloch, Jean-Francis; Thuo, Martin M

    2015-11-01

    Interest in low-cost diagnostic devices has recently gained attention, in part due to the rising cost of healthcare and the need to serve populations in resource-limited settings. A major challenge in the development of such devices is the need for hydrophobic barriers to contain polar bio-fluid analytes. Key approaches in lowering the cost in diagnostics have centered on (i) development of low-cost fabrication techniques/processes, (ii) use of affordable materials, or, (iii) minimizing the need for high-tech tools. This communication describes a simple, low-cost, adaptable, and portable method for patterning paper and subsequent use of the patterned paper in diagnostic tests. Our approach generates hydrophobic regions using a ball-point pen filled with a hydrophobizing molecule suspended in a solvent carrier. An empty ball-point pen was filled with a solution of trichloro perfluoroalkyl silane in hexanes (or hexadecane), and the pen used to draw lines on Whatman® chromatography 1 paper. The drawn regions defined the test zones since the trichloro silane reacts with the paper to give a hydrophobic barrier. The formation of the hydrophobic barriers is reaction kinetic and diffusion-limited, ensuring well defined narrow barriers. We performed colorimetric glucose assays and enzyme-linked immuno-sorbent assay (ELISA) using the created test zones. To demonstrate the versatility of this approach, we fabricated multiple devices on a single piece of paper and demonstrated the reproducibility of assays on these devices. The overall cost of devices fabricated by drawing are relatively lower (

  13. MESA - A new approach to low cost scientific spacecraft

    Science.gov (United States)

    Keyes, G. W.; Case, C. M.

    1982-09-01

    Today, the greatest obstacle to science and exploration in space is its cost. The present investigation is concerned with approaches for reducing this cost. Trends in the scientific spacecraft market are examined, and a description is presented for the MESA space platform concept. The cost drivers are considered, taking into account planning, technical aspects, and business factors. It is pointed out that the primary function of the MESA concept is to provide a satellite system at the lowest possible price. In order to reach this goal an attempt is made to benefit from all of the considered cost drivers. It is to be tried to work with the customer early in the mission analysis stage in order to assist in finding the right compromise between mission cost and return. A three phase contractual arrangement is recommended for MESA platforms. The phases are related to mission feasibility, specification definition, and design and development. Modular kit design promotes flexibility at low cost.

  14. A Rapid and Low-Cost PCR Thermal Cycler for Low Resource Settings.

    Directory of Open Access Journals (Sweden)

    Grace Wong

    Full Text Available Many modern molecular diagnostic assays targeting nucleic acids are typically confined to developed countries or to the national reference laboratories of developing-world countries. The ability to make technologies for the rapid diagnosis of infectious diseases broadly available in a portable, low-cost format would mark a revolutionary step forward in global health. Many molecular assays are also developed based on polymerase chain reactions (PCR, which require thermal cyclers that are relatively heavy (>20 pounds and need continuous electrical power. The temperature ramping speed of most economical thermal cyclers are relatively slow (2 to 3 °C/s so a polymerase chain reaction can take 1 to 2 hours. Most of all, these thermal cyclers are still too expensive ($2k to $4k for low-resource setting uses.In this article, we demonstrate the development of a low-cost and rapid water bath based thermal cycler that does not require active temperature control or continuous power supply during PCR. This unit costs $130 to build using commercial off-the-shelf items. The use of two or three vacuum-insulated stainless-steel Thermos food jars containing heated water (for denaturation and annealing/extension steps and a layer of oil on top of the water allow for significantly stabilized temperatures for PCR to take place. Using an Arduino-based microcontroller, we automate the "archaic" method of hand-transferring PCR tubes between water baths.We demonstrate that this innovative unit can deliver high speed PCR (17 s per PCR cycle with the potential to go beyond the 1,522 bp long amplicons tested in this study and can amplify from templates down to at least 20 copies per reaction. The unit also accepts regular PCR tubes and glass capillary tubes. The PCR efficiency of our thermal cycler is not different from other commercial thermal cyclers. When combined with a rapid nucleic acid detection approach, the thermos thermal cycler (TTC can enable on-site molecular

  15. THE APPLICATION AND DEVELOPMENT OF APPROPRIATE TOOLS AND TECHNOLOGIES FOR COST-EFFECTIVE CARBON SEQUESTRATION

    Energy Technology Data Exchange (ETDEWEB)

    Bill Stanley; Sandra Brown; Ellen Hawes; Zoe Kant; Miguel Calmon; Gilberto Tiepolo

    2002-09-01

    The Nature Conservancy is participating in a Cooperative Agreement with the Department of Energy (DOE) National Energy Technology Laboratory (NETL) to explore the compatibility of carbon sequestration in terrestrial ecosystems and the conservation of biodiversity. The title of the research projects is ''Application and Development of Appropriate Tools and Technologies for Cost-Effective Carbon Sequestration''. The objectives of the project are to: (1) improve carbon offset estimates produced in both the planning and implementation phases of projects; (2) build valid and standardized approaches to estimate project carbon benefits at a reasonable cost; and (3) lay the groundwork for implementing cost-effective projects, providing new testing ground for biodiversity protection and restoration projects that store additional atmospheric carbon. This Technical Progress Report discusses preliminary results of the six specific tasks that The Nature Conservancy is undertaking to answer research needs while facilitating the development of real projects with measurable greenhouse gas impacts. The specific tasks discussed include: Task 1: carbon inventory advancements; Task 2: advanced videography testing; Task 3: baseline method development; Task 4: third-party technical advisory panel meetings; Task 5: new project feasibility studies; and Task 6: development of new project software screening tool.

  16. Tools for Economic Analysis of Patient Management Interventions in Heart Failure Cost-Effectiveness Model: A Web-based program designed to evaluate the cost-effectiveness of disease management programs in heart failure.

    Science.gov (United States)

    Reed, Shelby D; Neilson, Matthew P; Gardner, Matthew; Li, Yanhong; Briggs, Andrew H; Polsky, Daniel E; Graham, Felicia L; Bowers, Margaret T; Paul, Sara C; Granger, Bradi B; Schulman, Kevin A; Whellan, David J; Riegel, Barbara; Levy, Wayne C

    2015-11-01

    Heart failure disease management programs can influence medical resource use and quality-adjusted survival. Because projecting long-term costs and survival is challenging, a consistent and valid approach to extrapolating short-term outcomes would be valuable. We developed the Tools for Economic Analysis of Patient Management Interventions in Heart Failure Cost-Effectiveness Model, a Web-based simulation tool designed to integrate data on demographic, clinical, and laboratory characteristics; use of evidence-based medications; and costs to generate predicted outcomes. Survival projections are based on a modified Seattle Heart Failure Model. Projections of resource use and quality of life are modeled using relationships with time-varying Seattle Heart Failure Model scores. The model can be used to evaluate parallel-group and single-cohort study designs and hypothetical programs. Simulations consist of 10,000 pairs of virtual cohorts used to generate estimates of resource use, costs, survival, and incremental cost-effectiveness ratios from user inputs. The model demonstrated acceptable internal and external validity in replicating resource use, costs, and survival estimates from 3 clinical trials. Simulations to evaluate the cost-effectiveness of heart failure disease management programs across 3 scenarios demonstrate how the model can be used to design a program in which short-term improvements in functioning and use of evidence-based treatments are sufficient to demonstrate good long-term value to the health care system. The Tools for Economic Analysis of Patient Management Interventions in Heart Failure Cost-Effectiveness Model provides researchers and providers with a tool for conducting long-term cost-effectiveness analyses of disease management programs in heart failure. Copyright © 2015 Elsevier Inc. All rights reserved.

  17. The Cost-Effectiveness of Low-Cost Essential Antihypertensive Medicines for Hypertension Control in China: A Modelling Study.

    Directory of Open Access Journals (Sweden)

    Dongfeng Gu

    2015-08-01

    Full Text Available Hypertension is China's leading cardiovascular disease risk factor. Improved hypertension control in China would result in result in enormous health gains in the world's largest population. A computer simulation model projected the cost-effectiveness of hypertension treatment in Chinese adults, assuming a range of essential medicines list drug costs.The Cardiovascular Disease Policy Model-China, a Markov-style computer simulation model, simulated hypertension screening, essential medicines program implementation, hypertension control program administration, drug treatment and monitoring costs, disease-related costs, and quality-adjusted life years (QALYs gained by preventing cardiovascular disease or lost because of drug side effects in untreated hypertensive adults aged 35-84 y over 2015-2025. Cost-effectiveness was assessed in cardiovascular disease patients (secondary prevention and for two blood pressure ranges in primary prevention (stage one, 140-159/90-99 mm Hg; stage two, ≥160/≥100 mm Hg. Treatment of isolated systolic hypertension and combined systolic and diastolic hypertension were modeled as a reduction in systolic blood pressure; treatment of isolated diastolic hypertension was modeled as a reduction in diastolic blood pressure. One-way and probabilistic sensitivity analyses explored ranges of antihypertensive drug effectiveness and costs, monitoring frequency, medication adherence, side effect severity, background hypertension prevalence, antihypertensive medication treatment, case fatality, incidence and prevalence, and cardiovascular disease treatment costs. Median antihypertensive costs from Shanghai and Yunnan province were entered into the model in order to estimate the effects of very low and high drug prices. Incremental cost-effectiveness ratios less than the per capita gross domestic product of China (11,900 international dollars [Int$] in 2015 were considered cost-effective. Treating hypertensive adults with prior

  18. Cost effective tools for soil organic carbon monitoring

    Science.gov (United States)

    Shepherd, Keith; Aynekulu, Ermias

    2013-04-01

    There is increasing demand for data on soil properties at fine spatial resolution to support management and planning decisions. Measurement of soil organic carbon has attracted much interest because (i) soil organic carbon is widely cited as a useful indicator of soil condition and (ii) of the importance of soil carbon in the global carbon cycle and climate mitigation strategies. However in considering soil measurement designs there has been insufficient attention given to careful analysis of the specific decisions that the measurements are meant to support and on what measurements have high information value for decision-making. As a result, much measurement effort may be wasted or focused on the wrong variables. A cost-effective measurement is one that reduces risk in decisions and does not cost more than the societal returns to additional evidence. A key uncertainty in measuring soil carbon as a soil condition indicator is what constitutes a good or bad level of carbon on a given soil. A measure of soil organic carbon concentration may have limited value for informing management decisions without the additional information required to interpret it, and so expending further efforts on improving measurements to increase precision may then have no value to improving the decision. Measuring soil carbon stock changes for carbon trading purposes requires high levels of measurement precision but there is still large uncertainty on whether the costs of measurement exceed the benefits. Since the largest cost component in soil monitoring is often travel to the field and physically sampling soils, it is generally cost-effective to meet multiple objectives by analysing a number of properties on a soil sample. Diffuse reflectance infrared spectroscopy is playing a key role in allowing multiple soil properties to be determined rapidly and at low cost. The method provides estimation of multiple soil properties (e.g. soil carbon, texture and mineralogy) in one measurement

  19. Feasibility of a low-cost hearing screening in rural Indiana

    Directory of Open Access Journals (Sweden)

    Khalid M. Khan

    2017-09-01

    Full Text Available Abstract Background Hearing loss remains a neglected public health issue in the rural and agricultural communities in the United States and therefore, promotion of a low-cost hearing screening may be important for these underserved populations. The major objectives of our study were to assess feasibility of a low-cost telephone-administered hearing test in rural Indiana and to identify the challenges, barriers and viable implementation strategies associated with this test. Also, we evaluated whether a focus group session could change the hearing health attitude of rural residents. Methods We recruited 126 adults from six rural Indiana counties who participated in study activities in the following order: 1 a pre-focus group demographic, knowledge and attitude survey, 2 a focus group for discussing the feasibility of a telephone-administered hearing screening, 3 a post focus group attitude survey and 4 hearing was screened using an audiometer and self-assessment scale. These activities generated both qualitative and quantitative data, which were subsequently analyzed. Results Hearing impairment was perceived as an important public health issue. Many participants expressed interests to try the low-cost National Hearing Test (NHT. However, participants recommended NHT to be facilitated by community organizations to provide access to landline phones. The focus group turned out to be an excellent awareness building activity producing significant improvement in hearing health attitudes. Comparison of self and audiometric evaluations indicated underestimation of hearing handicap in our rural study population. Conclusions The study results underscore the urgent need for an effective strategy to promote low-cost hearing screening in rural US communities.

  20. CAIRSENSE-Atlanta Low Cost Sensor Evaluation Versus Reference Monitors

    Data.gov (United States)

    U.S. Environmental Protection Agency — Short time interval comparisons of low cost sensor response and corresponding Federal Reference or Federal Equivalent Monitors at an NCOR site located in proximity...

  1. Low-Cost Monitoring System of Sensors for Evaluating Dynamic Solicitations of Semitrailer Structure

    Directory of Open Access Journals (Sweden)

    Pablo Luque

    2016-01-01

    Full Text Available Analysis of the fatigue life of a semitrailer structure necessitates identification of the loads and dynamic solicitations in the structure. These forces can be introduced in computer simulation software (multibody + finite element for analysing the response of different design solutions to them. These numerical models must be validated and some parameters need to be measured directly in a field test with real vehicles under various driving conditions. In this study, a low-cost monitoring system is developed for application to a real fleet of semitrailers. According to the definition of the numerical model, the guidance of a virtual vehicle is defined by the three-dimensional kinematics of the kingpin. For characterisation of these movements, a monitoring system having a low-cost inertial measurement unit (IMU and global positioning system (GPS antennas is developed with different configurations to enable analysis of the best cost-benefit (result accuracy solution, and an extended Kalman filter (EKF that characterises the kinematic guidance of the kingpin is proposed. A semitrailer was equipped with the experimental low-cost monitoring system and high-precision sensors (IMU, GPS in order to validate the results obtained by the experimental low-cost monitoring system and the inertial-extended Kalman filter developed. The validated system has applicability in the low-cost monitoring of a fleet of real vehicles.

  2. Clinical and cost effectiveness evaluation of low friction and shear garments.

    Science.gov (United States)

    Smith, G; Ingram, A

    2010-12-01

    To determine the effectiveness of Parafricta low-friction garments in reducing the incidence and prevalence of pressure ulceration and to evaluate the curative aspects of these products on pre-existing skin breakdown within a hospital setting. Patients with a Waterlow score of >15 and who were unable to reposition independently were offered the low-friction undergarments and bootees. A total of 650 patient cases were initially reviewed. Of these, 204 met the criteria for use of the products in the 3 months prior to the start of the evaluation (cohort 1) and 165 patients met the criteria during the period when the garments were used (cohort 2). Data collected included pressure ulcer incidence, location, grading, and outcome of ulcer on discharge. Locally derived costs for length of stay, wound dressings, pressure-redistributing mattresses and additional cost of the low-friction garments were applied to build a cost-effectiveness model. In patients at risk of skin breakdown there was a statistically significant reduction in the number of patients who developed pressure ulcers following use of the low-friction garments in cohort 2 when compared with cohort 1 (16% reduction; p = 0.0286). In addition, the number of patients who were ulcer free on admission but who developed ulcers and then improved or completely healed before discharge was also statistically significant (41% increase; p = 0.0065) when cohort 2 was compared with cohort 1. Fewer patients admitted with ulcers deteriorated when using the low-friction garments (21% reduction; p = 0.0012). The costs, which were calculated by comparing patient throughput for these patients, suggest that the savings associated with preventing skin breakdown outweighed the cost of the products used (base case model indicated a saving of over £63,000 per 100 at risk patients). The results support the conclusion that low-friction garment products have a role to play in the prevention of skin breakdown, and appear to be both

  3. Cost-effectiveness analysis of main diagnosis tools in women with overactive bladder. Clinical history, micturition diary and urodynamic study.

    Science.gov (United States)

    López-Fando, L; Carracedo, D; Jiménez, M; Gómez de Vicente, J M; Martínez, L; Gómez-Cañizo, C; Gómez, V; Burgos, F J

    2015-01-01

    The aim of the present clinical research is to analyze, in the light of the best scientific evidence, the performance and the cost of the main diagnostic tools for overactive bladder (OAB). It is an exploratory transversal study in which 199 women diagnosed of OAB between 2006 and 2008 were selected and underwent to following prospective analyses: physical examination, urine analysis, micturition diary (MD) and urodynamic study (UDS). A percentage of 80% was assumed as highly sensitive and a diagnostic difference among tests of 10% would be considered clinically relevant. Tests' sensitivity for diagnosis of OAB was statistically established by two ways: isolated and combined. Besides, the direct and indirect costs of these tests performance were conducted. Cost-effectiveness study of clinical history (CH), MD and US for the diagnosis of OAB was performed. Overall sensitivity for OAB diagnosis is low for the 3 tests used in isolated way, whilst the combination of any two tests shows good overall sensitivity. The combination of CH and MD has appeared as the most cost-effective alternative to OAB diagnosis. For OAB diagnosis, CH-DM combination shows the same sensitivity than the association of either of them with the UDS, but unlike to these, it shows the lowest cost. Copyright © 2013 AEU. Publicado por Elsevier España, S.L.U. All rights reserved.

  4. Capital cost: high and low sulfur coal plants-1200 MWe. [High sulfur coal

    Energy Technology Data Exchange (ETDEWEB)

    1977-01-01

    This Commercial Electric Power Cost Study for 1200 MWe (Nominal) high and low sulfur coal plants consists of three volumes. The high sulfur coal plant is described in Volumes I and II, while Volume III describes the low sulfur coal plant. The design basis and cost estimate for the 1232 MWe high sulfur coal plant is presented in Volume I, and the drawings, equipment list and site description are contained in Volume II. The reference design includes a lime flue gas desulfurization system. A regenerative sulfur dioxide removal system using magnesium oxide is also presented as an alternate in Section 7 Volume II. The design basis, drawings and summary cost estimate for a 1243 MWe low sulfur coal plant are presented in Volume III. This information was developed by redesigning the high sulfur coal plant for burning low sulfur sub-bituminous coal. These coal plants utilize a mechanical draft (wet) cooling tower system for condenser heat removal. Costs of alternate cooling systems are provided in Report No. 7 in this series of studies of costs of commercial electrical power plants.

  5. An overview of recent progress using low-cost and cost-effective composite materials and processes to produce SSC magnet coils and associated non-metallic parts

    International Nuclear Information System (INIS)

    Morena, J.

    1992-01-01

    Thermoplastic and thermoset polymer systems have been used in high-energy physics applications throughout the world for many years. Like other industries and industrial communities, the materials and processes requirements of these polymers have recently taken on new meanings. New accelerators and other machines are pushing all material parameters beyond limits. New polymeric and composite materials are being developed, invented, and formulated, as is new process and application equipment. This is a decade of change. Composite materials are being chosen for performance characteristics and cost-effective processing as well. The information that follows will note some of the recent progress in the development of composite materials and processes for producing low-cost and cost-effective, high-quality, non-metallic composite components for use in SSC magnets and in other accelerators. The materials and methods for making composite molds, tools, and structural parts for magnet coils and other components are demonstrated. New, unique, and innovative approaches for processing thermoset polymers are presented. The formulated polymer systems are used to form semi and structural insulators, spacers, supports, coil end parts, blocks, housings, adhesives, and other composite applications

  6. New security features and their impact on low-cost note readers

    Science.gov (United States)

    Bernardini, Ronald R.

    2004-06-01

    Banknote security features are evolving and changing. New features are constantly being developed and slowly being incorporated into banknotes. The assumption is that these features make the notes more secure for everyone; but do they? This paper looks at some of the features incorporated in today's banknotes and how (or if) they add security to banknotes processed by low cost banknote readers. The sensing technology used in low cost note readers has changed somewhat in the last few years but the industry is still faced by the cost constraints of a very competitive market. Some of the new note features require high-resolution image capture, complex optical measurements or expensive emission/detection devices. Paper watermarks, digital watermarks, OVI, Holograms, Stokes conversion, IR and magnetic features are examined, as well as the technologies used and the relative cost/benefit developed for these note features.

  7. Low cost earthquake resistant ferrocement small house

    International Nuclear Information System (INIS)

    Saleem, M.A.; Ashraf, M.; Ashraf, M.

    2008-01-01

    The greatest humanitarian challenge faced even today after one year of Kashmir Hazara earthquake is that of providing shelter. Currently on the globe one in seven people live in a slum or refugee camp. The earthquake of October 2005 resulted in a great loss of life and property. This research work is mainly focused on developing a design of small size, low cost and earthquake resistant house. Ferrocement panels are recommended as the main structural elements with lightweight truss roofing system. Earthquake resistance is ensured by analyzing the structure on ETABS for a seismic activity of zone 4. The behavior of structure is found satisfactory under the earthquake loading. An estimate of cost is also presented which shows that it is an economical solution. (author)

  8. High Efficiency, Low Cost Scintillators for PET

    International Nuclear Information System (INIS)

    Kanai Shah

    2007-01-01

    Inorganic scintillation detectors coupled to PMTs are an important element of medical imaging applications such as positron emission tomography (PET). Performance as well as cost of these systems is limited by the properties of the scintillation detectors available at present. The Phase I project was aimed at demonstrating the feasibility of producing high performance scintillators using a low cost fabrication approach. Samples of these scintillators were produced and their performance was evaluated. Overall, the Phase I effort was very successful. The Phase II project will be aimed at advancing the new scintillation technology for PET. Large samples of the new scintillators will be produced and their performance will be evaluated. PET modules based on the new scintillators will also be built and characterized

  9. Application and Development of Appropriate Tools and Technologies for Cost-Effective Carbon Sequestration

    Energy Technology Data Exchange (ETDEWEB)

    Bill Stanley; Sandra Brown; Patrick Gonzalez; Brent Sohngen; Neil Sampson; Mark Anderson; Miguel Calmon; Sean Grimland; Ellen Hawes; Zoe Kant; Dan Morse; Sarah Woodhouse Murdock; Arlene Olivero; Tim Pearson; Sarah Walker; Jon Winsten; Chris Zganjar

    2006-09-30

    The Nature Conservancy is participating in a Cooperative Agreement with the Department of Energy (DOE) National Energy Technology Laboratory (NETL) to explore the compatibility of carbon sequestration in terrestrial ecosystems and the conservation of biodiversity. The title of the research project is ''Application and Development of Appropriate Tools and Technologies for Cost-Effective Carbon Sequestration''. The objectives of the project are to: (1) improve carbon offset estimates produced in both the planning and implementation phases of projects; (2) build valid and standardized approaches to estimate project carbon benefits at a reasonable cost; and (3) lay the groundwork for implementing cost-effective projects, providing new testing ground for biodiversity protection and restoration projects that store additional atmospheric carbon. This Technical Progress Report discusses preliminary results of the six specific tasks that The Nature Conservancy is undertaking to answer research needs while facilitating the development of real projects with measurable greenhouse gas reductions. The research described in this report occurred between April 1st and July 30th 2006. The specific tasks discussed include: Task 1: carbon inventory advancements; Task 2: emerging technologies for remote sensing of terrestrial carbon; Task 3: baseline method development; Task 4: third-party technical advisory panel meetings; Task 5: new project feasibility studies; and Task 6: development of new project software screening tool.

  10. Application and Development of Appropriate Tools and Technologies for Cost-Effective Carbon Sequestration

    Energy Technology Data Exchange (ETDEWEB)

    Bill Stanley; Patrick Gonzalez; Sandra Brown; Jenny Henman; Zoe Kant; Sarah Woodhouse Murdock; Neil Sampson; Gilberto Tiepolo; Tim Pearson; Sarah Walker; Miguel Calmon

    2006-01-01

    The Nature Conservancy is participating in a Cooperative Agreement with the Department of Energy (DOE) National Energy Technology Laboratory (NETL) to explore the compatibility of carbon sequestration in terrestrial ecosystems and the conservation of biodiversity. The title of the research project is ''Application and Development of Appropriate Tools and Technologies for Cost-Effective Carbon Sequestration''. The objectives of the project are to: (1) improve carbon offset estimates produced in both the planning and implementation phases of projects; (2) build valid and standardized approaches to estimate project carbon benefits at a reasonable cost; and (3) lay the groundwork for implementing cost-effective projects, providing new testing ground for biodiversity protection and restoration projects that store additional atmospheric carbon. This Technical Progress Report discusses preliminary results of the six specific tasks that The Nature Conservancy is undertaking to answer research needs while facilitating the development of real projects with measurable greenhouse gas reductions. The research described in this report occurred between April 1st , 2005 and June 30th, 2005. The specific tasks discussed include: Task 1: carbon inventory advancements; Task 2: emerging technologies for remote sensing of terrestrial carbon; Task 3: baseline method development; Task 4: third-party technical advisory panel meetings; Task 5: new project feasibility studies; and Task 6: development of new project software screening tool.

  11. Application and Development of Appropriate Tools and Technologies for Cost-Effective Carbon Sequestration

    Energy Technology Data Exchange (ETDEWEB)

    Bill Stanley; Patrick Gonzalez; Sandra Brown; Jenny Henman; Sarah Woodhouse Murdock; Neil Sampson; Tim Pearson; Sarah Walker; Zoe Kant; Miguel Calmon

    2006-04-01

    The Nature Conservancy is participating in a Cooperative Agreement with the Department of Energy (DOE) National Energy Technology Laboratory (NETL) to explore the compatibility of carbon sequestration in terrestrial ecosystems and the conservation of biodiversity. The title of the research project is ''Application and Development of Appropriate Tools and Technologies for Cost-Effective Carbon Sequestration''. The objectives of the project are to: (1) improve carbon offset estimates produced in both the planning and implementation phases of projects; (2) build valid and standardized approaches to estimate project carbon benefits at a reasonable cost; and (3) lay the groundwork for implementing cost-effective projects, providing new testing ground for biodiversity protection and restoration projects that store additional atmospheric carbon. This Technical Progress Report discusses preliminary results of the six specific tasks that The Nature Conservancy is undertaking to answer research needs while facilitating the development of real projects with measurable greenhouse gas reductions. The research described in this report occurred between January 1st and March 31st 2006. The specific tasks discussed include: Task 1: carbon inventory advancements; Task 2: emerging technologies for remote sensing of terrestrial carbon; Task 3: baseline method development; Task 4: third-party technical advisory panel meetings; Task 5: new project feasibility studies; and Task 6: development of new project software screening tool.

  12. Application and Development of Appropriate Tools and Technologies for Cost-Effective Carbon Sequestration

    Energy Technology Data Exchange (ETDEWEB)

    Bill Stanley; Sandra Brown; Patrick Gonzalez; Brent Sohngen; Neil Sampson; Mark Anderson; Miguel Calmon; Sean Grimland; Zoe Kant; Dan Morse; Sarah Woodhouse Murdock; Arlene Olivero; Tim Pearson; Sarah Walker; Jon Winsten; Chris Zganjar

    2007-03-31

    The Nature Conservancy is participating in a Cooperative Agreement with the Department of Energy (DOE) National Energy Technology Laboratory (NETL) to explore the compatibility of carbon sequestration in terrestrial ecosystems and the conservation of biodiversity. The title of the research project is ''Application and Development of Appropriate Tools and Technologies for Cost-Effective Carbon Sequestration''. The objectives of the project are to: (1) improve carbon offset estimates produced in both the planning and implementation phases of projects; (2) build valid and standardized approaches to estimate project carbon benefits at a reasonable cost; and (3) lay the groundwork for implementing cost-effective projects, providing new testing ground for biodiversity protection and restoration projects that store additional atmospheric carbon. This Technical Progress Report discusses preliminary results of the six specific tasks that The Nature Conservancy is undertaking to answer research needs while facilitating the development of real projects with measurable greenhouse gas reductions. The research described in this report occurred between January 1st and March 31st 2007. The specific tasks discussed include: Task 1--carbon inventory advancements; Task 2--emerging technologies for remote sensing of terrestrial carbon; Task 3--baseline method development; Task 4--third-party technical advisory panel meetings; Task 5--new project feasibility studies; and Task 6--development of new project software screening tool.

  13. Application and Development of Appropriate Tools and Technologies for Cost-Effective Carbon Sequestration

    Energy Technology Data Exchange (ETDEWEB)

    Bill Stanley; Patrick Gonzalez; Sandra Brown; Sarah Woodhouse Murdock; Jenny Henman; Zoe Kant; Gilberto Tiepolo; Tim Pearson; Neil Sampson; Miguel Calmon

    2005-10-01

    The Nature Conservancy is participating in a Cooperative Agreement with the Department of Energy (DOE) National Energy Technology Laboratory (NETL) to explore the compatibility of carbon sequestration in terrestrial ecosystems and the conservation of biodiversity. The title of the research project is ''Application and Development of Appropriate Tools and Technologies for Cost-Effective Carbon Sequestration''. The objectives of the project are to: (1) improve carbon offset estimates produced in both the planning and implementation phases of projects; (2) build valid and standardized approaches to estimate project carbon benefits at a reasonable cost; and (3) lay the groundwork for implementing cost-effective projects, providing new testing ground for biodiversity protection and restoration projects that store additional atmospheric carbon. This Technical Progress Report discusses preliminary results of the six specific tasks that The Nature Conservancy is undertaking to answer research needs while facilitating the development of real projects with measurable greenhouse gas reductions. The research described in this report occurred between April 1st , 2005 and June 30th, 2005. The specific tasks discussed include: Task 1: carbon inventory advancements; Task 2: emerging technologies for remote sensing of terrestrial carbon; Task 3: baseline method development; Task 4: third-party technical advisory panel meetings; Task 5: new project feasibility studies; and Task 6: development of new project software screening tool.

  14. Application and Development of Appropriate Tools and Technologies for Cost-Effective Carbon Sequestration

    Energy Technology Data Exchange (ETDEWEB)

    Bill Stanley; Sandra Brown; Patrick Gonzalez; Zoe Kant; Gilberto Tiepolo; Wilber Sabido; Ellen Hawes; Jenny Henman; Miguel Calmon; Michael Ebinger

    2004-07-10

    The Nature Conservancy is participating in a Cooperative Agreement with the Department of Energy (DOE) National Energy Technology Laboratory (NETL) to explore the compatibility of carbon sequestration in terrestrial ecosystems and the conservation of biodiversity. The title of the research project is ''Application and Development of Appropriate Tools and Technologies for Cost-Effective Carbon Sequestration''. The objectives of the project are to: (1) improve carbon offset estimates produced in both the planning and implementation phases of projects; (2) build valid and standardized approaches to estimate project carbon benefits at a reasonable cost; and (3) lay the groundwork for implementing cost-effective projects, providing new testing ground for biodiversity protection and restoration projects that store additional atmospheric carbon. This Technical Progress Report discusses preliminary results of the six specific tasks that The Nature Conservancy is undertaking to answer research needs while facilitating the development of real projects with measurable greenhouse gas impacts. The research described in this report occurred between July 1, 2002 and June 30, 2003. The specific tasks discussed include: Task 1: carbon inventory advancements; Task 2: remote sensing for carbon analysis; Task 3: baseline method development; Task 4: third-party technical advisory panel meetings; Task 5: new project feasibility studies; and Task 6: development of new project software screening tool.

  15. Microinsurance: innovations in low-cost health insurance.

    Science.gov (United States)

    Dror, David M; Radermacher, Ralf; Khadilkar, Shrikant B; Schout, Petra; Hay, François-Xavier; Singh, Arbind; Koren, Ruth

    2009-01-01

    Microinsurance--low-cost health insurance based on a community, cooperative, or mutual and self-help arrangements-can provide financial protection for poor households and improve access to health care. However, low benefit caps and a low share of premiums paid as benefits--both designed to keep these arrangements in business--perversely limited these schemes' ability to extend coverage, offer financial protection, and retain members. We studied three schemes in India, two of which are member-operated and one a commercial scheme, using household surveys of insured and uninsured households and interviews with managers. All three enrolled poor households and raised their use of hospital services, as intended. Financial exposure was greatest, and protection was least, in the commercial scheme, which imposed the lowest caps on benefits and where income was the lowest.

  16. IMPLEMENTATION AND TESTING OF LOW COST UAV PLATFORM FOR ORTHOPHOTO IMAGING

    Directory of Open Access Journals (Sweden)

    D. Brucas

    2013-08-01

    Full Text Available Implementation of Unmanned Aerial Vehicles for civilian applications is rapidly increasing. Technologies which were expensive and available only for military use have recently spread on civilian market. There is a vast number of low cost open source components and systems for implementation on UAVs available. Using of low cost hobby and open source components ensures considerable decrease of UAV price, though in some cases compromising its reliability. In Space Science and Technology Institute (SSTI in collaboration with Vilnius Gediminas Technical University (VGTU researches have been performed in field of constructing and implementation of small UAVs composed of low cost open source components (and own developments. Most obvious and simple implementation of such UAVs – orthophoto imaging with data download and processing after the flight. The construction, implementation of UAVs, flight experience, data processing and data implementation will be further covered in the paper and presentation.

  17. Implementation and Testing of Low Cost Uav Platform for Orthophoto Imaging

    Science.gov (United States)

    Brucas, D.; Suziedelyte-Visockiene, J.; Ragauskas, U.; Berteska, E.; Rudinskas, D.

    2013-08-01

    Implementation of Unmanned Aerial Vehicles for civilian applications is rapidly increasing. Technologies which were expensive and available only for military use have recently spread on civilian market. There is a vast number of low cost open source components and systems for implementation on UAVs available. Using of low cost hobby and open source components ensures considerable decrease of UAV price, though in some cases compromising its reliability. In Space Science and Technology Institute (SSTI) in collaboration with Vilnius Gediminas Technical University (VGTU) researches have been performed in field of constructing and implementation of small UAVs composed of low cost open source components (and own developments). Most obvious and simple implementation of such UAVs - orthophoto imaging with data download and processing after the flight. The construction, implementation of UAVs, flight experience, data processing and data implementation will be further covered in the paper and presentation.

  18. Comparison of costs for alternative mixed low-level waste treatment systems

    International Nuclear Information System (INIS)

    Schwinkendorf, W.E.; Harvego, L.; Cooley, C.R.; Biagi, C.

    1996-01-01

    Total life cycle costs (TLCCs), including disposal costs, of thermal, nonthermal and enhanced nonthermal systems were evaluated to guide future research and development programs for the treatment of mixed low-level waste (MLLW) consisting of RCRA hazardous and low-level radioactive wastes. In these studies, nonthermal systems are defined as those systems that process waste at temperatures less than 350 C. Preconceptual designs and costs were developed for thirty systems with a capacity (2,927 lbs/hr) to treat the DOE MLLW stored inventor y(approximately 236 million pounds) in 20 years in a single, centralized facility. A limited comparison of the studies' results is presented in this paper. Sensitivity of treatment costs with respect to treatment capacity, number of treatment facilities, and system availability were also determined. The major cost element is operations and maintenance (O and M), which is 50 to 60% of the TLCC for both thermal and nonthermal systems. Energy costs constitute a small fraction (< 1%) of the TLCCs. Equipment cost is only 3 to 5% of the treatment cost. Evaluation of subsystem costs demonstrate that receiving and preparation is the highest cost subsystem at about 25 to 30% of the TLCC for both thermal and nonthermal systems. These studies found no cost incentives to use nonthermal or hybrid (combined nonthermal treatment with stabilization by vitrification) systems in place of thermal systems. However, there may be other incentives including fewer air emissions and less local objection to a treatment facility. Building multiple treatment facilities to treat the same total mass of waste as a single facility would increase the total treatment cost significantly, and improved system availability decreases unit treatment costs by 17% to 30%

  19. Low-cost digital counting interface for fermentation gas measurement

    Energy Technology Data Exchange (ETDEWEB)

    Erdman, M.D.; Deluiche, S.R.

    1985-05-01

    Laboratory- and pilot-scale volumetric measurement of fermentation gas can be readily determined with a standard wet-test gas meter. The initial cost of the meter, however, is quite prohibitive for experimental work and researchers have searched for other means of quantifying gas production. Techniques using calibrated floating gas holders, liquid displacement, flexible membranes, and conventional gas meters have been reported. Many of these methods lack a high degree of accuracy for small gas volumes. Residential gas meters such as those manufactured by Singer company, and others appear well suited for this application as long as a relatively dry gas is passed through the meter and a method is developed to subdivide the meter scale and record the results. The objective of this report was to construct a low cost, accurate, digital counting interface for concurrent operation with a low cost bellows-type gas meter. Although initially constructed for use in gas measurement studies, the interface can be used in other applications where digital output or computer interfacing are desired. 2 references.

  20. Silicon web process development. [for low cost solar cells

    Science.gov (United States)

    Duncan, C. S.; Hopkins, R. H.; Seidensticker, R. G.; Mchugh, J. P.; Hill, F. E.; Heimlich, M. E.; Driggers, J. M.

    1979-01-01

    Silicon dendritic web, a single crystal ribbon shaped during growth by crystallographic forces and surface tension (rather than dies), is a highly promising base material for efficient low cost solar cells. The form of the product smooth, flexible strips 100 to 200 microns thick, conserves expensive silicon and facilitates automation of crystal growth and the subsequent manufacturing of solar cells. These characteristics, coupled with the highest demonstrated ribbon solar cell efficiency-15.5%-make silicon web a leading candidate to achieve, or better, the 1986 Low Cost Solar Array (LSA) Project cost objective of 50 cents per peak watt of photovoltaic output power. The main objective of the Web Program, technology development to significantly increase web output rate, and to show the feasibility for simultaneous melt replenishment and growth, have largely been accomplished. Recently, web output rates of 23.6 sq cm/min, nearly three times the 8 sq cm/min maximum rate of a year ago, were achieved. Webs 4 cm wide or greater were grown on a number of occassions.

  1. Low-cost non-fluorinated membranes for fuel cells

    CSIR Research Space (South Africa)

    Luo, H

    2010-08-31

    Full Text Available the driver of the next growth wave of the world’s economy. A proton conductive membrane is the core of the polymer electrolyte membrane fuel cell (PEMFC). Presently, Nafion® membranes are widely used in PEMFC. However, the high cost, low operation temperature...

  2. Low Cost Rapid Response Spacecraft, (LCRRS): A Research Project in Low Cost Spacecraft Design and Fabrication in a Rapid Prototyping Environment

    Science.gov (United States)

    Spremo, Stevan; Bregman, Jesse; Dallara, Christopher D.; Ghassemieh, Shakib M.; Hanratty, James; Jackson, Evan; Kitts, Christopher; Klupar, Pete; Lindsay, Michael; Ignacio, Mas; hide

    2009-01-01

    The Low Cost Rapid Response Spacecraft (LCRRS) is an ongoing research development project at NASA Ames Research Center (ARC), Moffett Field, California. The prototype spacecraft, called Cost Optimized Test for Spacecraft Avionics and Technologies (COTSAT) is the first of what could potentially be a series of rapidly produced low-cost satellites. COTSAT has a target launch date of March 2009 on a SpaceX Falcon 9 launch vehicle. The LCRRS research system design incorporates use of COTS (Commercial Off The Shelf), MOTS (Modified Off The Shelf), and GOTS (Government Off The Shelf) hardware for a remote sensing satellite. The design concept was baselined to support a 0.5 meter Ritchey-Chretien telescope payload. This telescope and camera system is expected to achieve 1.5 meter/pixel resolution. The COTSAT team is investigating the possibility of building a fully functional spacecraft for $500,000 parts and $2,000,000 labor. Cost is dramatically reduced by using a sealed container, housing the bus and payload subsystems. Some electrical and RF designs were improved/upgraded from GeneSat-1 heritage systems. The project began in January 2007 and has yielded two functional test platforms. It is expected that a flight-qualified unit will be finished in December 2008. Flight quality controls are in place on the parts and materials used in this development with the aim of using them to finish a proto-flight satellite. For LEO missions the team is targeting a mission class requiring a minimum of six months lifetime or more. The system architecture incorporates several design features required by high reliability missions. This allows for a true skunk works environment to rapidly progress toward a flight design. Engineering and fabrication is primarily done in-house at NASA Ames with flight certifications on materials. The team currently employs seven Full Time Equivalent employees. The success of COTSATs small team in this effort can be attributed to highly cross trained

  3. A strategy for low cost development of incremental oil in legacy reservoirs

    Science.gov (United States)

    Attanasi, E.D.

    2016-01-01

    The precipitous decline in oil prices during 2015 has forced operators to search for ways to develop low-cost and low-risk oil reserves. This study examines strategies to low cost development of legacy reservoirs, particularly those which have already implemented a carbon dioxide enhanced oil recovery (CO2 EOR) program. Initially the study examines the occurrence and nature of the distribution of the oil resources that are targets for miscible and near-miscible CO2 EOR programs. The analysis then examines determinants of technical recovery through the analysis of representative clastic and carbonate reservoirs. The economic analysis focusses on delineating the dominant components of investment and operational costs. The concluding sections describe options to maximize the value of assets that the operator of such a legacy reservoir may have that include incremental expansion within the same producing zone and to producing zones that are laterally or stratigraphically near main producing zones. The analysis identified the CO2 recycle plant as the dominant investment cost item and purchased CO2 and liquids management as a dominant operational cost items. Strategies to utilize recycle plants for processing CO2 from multiple producing zones and multiple reservoir units can significantly reduce costs. Industrial sources for CO2 should be investigated as a possibly less costly way of meeting EOR requirements. Implementation of tapered water alternating gas injection schemes can partially mitigate increases in fluid lifting costs.

  4. Design of Low Cost, Highly Adsorbent Activated Carbon Fibers

    National Research Council Canada - National Science Library

    Mangun, Christian

    2003-01-01

    .... EKOS has developed a novel activated carbon fiber - (ACF) that combines the low cost and durability of GAC with tailored pore size and pore surface chemistry for improved defense against chemical agents...

  5. Investigation of a new low cost and low consumption single poly-silicon memory

    Directory of Open Access Journals (Sweden)

    Patrick Calenzo

    2010-10-01

    Full Text Available In this paper is presented an investigation on a new low cost and voltage consumption single poly-silicon memory cell for passive RFID (Radio Frequency IDentificationapplications. This structure is low cost due to its single poly-silicon design. This memory cell has two particularities : the first one is that no deported capacitor is necessary to program this cell which allows to reduce the structure size to 1.1μm². The second one is the way the cell is erased. A Zener diode is used to generate carriers in order to be injected into the floating gate. This Zener diode is one of the key points for the functionality that has to be validated with some electrical trials. These trials permit to integrate and use the Zener diodes measured in simulations of the complete memory cell. This is done to validate the best candidate between the Zener diodes used for the cell and highlight the efficiency in consumption and rapidity to erase the cell. Besides, the writing and the reading cases are simulated in order to show the low consumption required by the cell during these phases.

  6. Low cost sonoluminescence experiment in pressurized water

    Science.gov (United States)

    Bernal, L.; Insabella, M.; Bilbao, L.

    2012-06-01

    We present a low cost design for demostration and mesurements of light emmision from a sonoluminescence experiment. Using presurized water introduced in an acrylic cylinder and one piezoelectric from an ultrasonic cleaner, we are able to generate cavitacion zones with emission of light. The use of argon to pressurize the water improves the emission an the light can be seen at naked eye in a softlit ambient.

  7. Low cost sonoluminescence experiment in pressurized water

    Energy Technology Data Exchange (ETDEWEB)

    Bernal, L; Insabella, M [LADOP, University of Mar del Plata (Argentina); Bilbao, L [INFIP, University of Buenos Aires and CONICET (Argentina)

    2012-06-19

    We present a low cost design for demostration and mesurements of light emission from a sonoluminescence experiment. Using pressurized water introduced in an acrylic cylinder and one piezoelectric from an ultrasonic cleaner, we are able to generate cavitacion zones with emission of light. The use of argon to pressurize the water improves the emission an the light can be seen at naked eye in a softlit ambient.

  8. Low cost sonoluminescence experiment in pressurized water

    International Nuclear Information System (INIS)

    Bernal, L; Insabella, M; Bilbao, L

    2012-01-01

    We present a low cost design for demostration and mesurements of light emission from a sonoluminescence experiment. Using pressurized water introduced in an acrylic cylinder and one piezoelectric from an ultrasonic cleaner, we are able to generate cavitacion zones with emission of light. The use of argon to pressurize the water improves the emission an the light can be seen at naked eye in a softlit ambient.

  9. Low-cost interferometric TDM technology for dynamic sensing applications

    Science.gov (United States)

    Bush, Jeff; Cekorich, Allen

    2004-12-01

    A low-cost design approach for Time Division Multiplexed (TDM) fiber-optic interferometric interrogation of multi-channel sensor arrays is presented. This paper describes the evolutionary design process of the subject design. First, the requisite elements of interferometric interrogation are defined for a single channel sensor. The concept is then extended to multi-channel sensor interrogation implementing a TDM multiplex scheme where "traditional" design elements are utilized. The cost of the traditional TDM interrogator is investigated and concluded to be too high for entry into many markets. A new design approach is presented which significantly reduces the cost for TDM interrogation. This new approach, in accordance with the cost objectives, shows promise to bring this technology to within the threshold of commercial acceptance for a wide range of distributed fiber sensing applications.

  10. Low-cost far infrared bolometer camera for automotive use

    Science.gov (United States)

    Vieider, Christian; Wissmar, Stanley; Ericsson, Per; Halldin, Urban; Niklaus, Frank; Stemme, Göran; Källhammer, Jan-Erik; Pettersson, Håkan; Eriksson, Dick; Jakobsen, Henrik; Kvisterøy, Terje; Franks, John; VanNylen, Jan; Vercammen, Hans; VanHulsel, Annick

    2007-04-01

    A new low-cost long-wavelength infrared bolometer camera system is under development. It is designed for use with an automatic vision algorithm system as a sensor to detect vulnerable road users in traffic. Looking 15 m in front of the vehicle it can in case of an unavoidable impact activate a brake assist system or other deployable protection system. To achieve our cost target below €100 for the sensor system we evaluate the required performance and can reduce the sensitivity to 150 mK and pixel resolution to 80 x 30. We address all the main cost drivers as sensor size and production yield along with vacuum packaging, optical components and large volume manufacturing technologies. The detector array is based on a new type of high performance thermistor material. Very thin Si/SiGe single crystal multi-layers are grown epitaxially. Due to the resulting valence barriers a high temperature coefficient of resistance is achieved (3.3%/K). Simultaneously, the high quality crystalline material provides very low 1/f-noise characteristics and uniform material properties. The thermistor material is transferred from the original substrate wafer to the read-out circuit using adhesive wafer bonding and subsequent thinning. Bolometer arrays can then be fabricated using industry standard MEMS process and materials. The inherently good detector performance allows us to reduce the vacuum requirement and we can implement wafer level vacuum packaging technology used in established automotive sensor fabrication. The optical design is reduced to a single lens camera. We develop a low cost molding process using a novel chalcogenide glass (GASIR®3) and integrate anti-reflective and anti-erosion properties using diamond like carbon coating.

  11. Low-Cost Production of Photonic Bandgap Materials Through Bubbling

    National Research Council Canada - National Science Library

    O'Brien, Daniel J; Wetzel, Eric D

    2007-01-01

    .... This report proposes a simple low-cost method for PBGM production. A device has been constructed that produces micrometer-sized, monodisperse bubbles that can be assembled into a crystal lattice by surface tension...

  12. Selecting and Ranking Cost Research Projects

    Science.gov (United States)

    1993-09-01

    Model (STACM) Enhancements Automated Cost Estimating Integrated Tools ( ACEIT ) Libraries BM/C 3 GEP Engineering and Cost BM/C 3 EP Engineering and Cost...50K NOM VHI 0.02635481 STACM ENHANCEMENTS NOM អK NOM VHI 0.02468682 ACEIT LIBRARIES VHI 50-IOOK HI VHI 0.06357704 GEP ENGRG. & COST VHI 100-150K VHl...0.02505922 SCATS LOW អK NOM VIII 0.02468682 PICES SUPPORT NOM 50-100K NOM VlIl 0.02455186 ACEIT SUPPORT VIII 50-100K VHI VHI 0.08208244 GUARDIAN

  13. Low Cost Digital Vibration Meter.

    Science.gov (United States)

    Payne, W Vance; Geist, Jon

    2007-01-01

    This report describes the development of a low cost, digital Micro Electro Mechanical System (MEMS) vibration meter that reports an approximation to the RMS acceleration of the vibration to which the vibration meter is subjected. The major mechanical element of this vibration meter is a cantilever beam, which is on the order of 500 µm in length, with a piezoresistor deposited at its base. Vibration of the device in the plane perpendicular to the cantilever beam causes it to bend, which produces a measurable change in the resistance of a piezoresistor. These changes in resistance along with a unique signal-processing scheme are used to determine an approximation to the RMS acceleration sensed by the device.

  14. A high-performance, low-cost, leading edge discriminator

    Indian Academy of Sciences (India)

    Abstract. A high-performance, low-cost, leading edge discriminator has been designed with a timing performance comparable to state-of-the-art, commercially available discrim- inators. A timing error of 16 ps is achieved under ideal operating conditions. Under more realistic operating conditions the discriminator displays a ...

  15. Low-cost high-quality crystalline germanium based flexible devices

    KAUST Repository

    Nassar, Joanna M.

    2014-06-16

    High performance flexible electronics promise innovative future technology for various interactive applications for the pursuit of low-cost, light-weight, and multi-functional devices. Thus, here we show a complementary metal oxide semiconductor (CMOS) compatible fabrication of flexible metal-oxide-semiconductor capacitors (MOSCAPs) with high-κ/metal gate stack, using a physical vapor deposition (PVD) cost-effective technique to obtain a high-quality Ge channel. We report outstanding bending radius ~1.25 mm and semi-transparency of 30%.

  16. Low-cost high-quality crystalline germanium based flexible devices

    KAUST Repository

    Nassar, Joanna M.; Hussain, Aftab M.; Rojas, Jhonathan Prieto; Hussain, Muhammad Mustafa

    2014-01-01

    High performance flexible electronics promise innovative future technology for various interactive applications for the pursuit of low-cost, light-weight, and multi-functional devices. Thus, here we show a complementary metal oxide semiconductor (CMOS) compatible fabrication of flexible metal-oxide-semiconductor capacitors (MOSCAPs) with high-κ/metal gate stack, using a physical vapor deposition (PVD) cost-effective technique to obtain a high-quality Ge channel. We report outstanding bending radius ~1.25 mm and semi-transparency of 30%.

  17. Using Low Cost Environmental Sensors in Geoscience Education

    Science.gov (United States)

    Leeman, J.; Ammon, C. J.; Anandakrishnan, S.

    2014-12-01

    Advances in process technology have drastically reduced the cost of manufacturing almost every type of sensor and micro-controller, putting low-to-mid grade sensor technology in the reach of educators and hobbyists. We demonstrate how a low cost magnetometer and an Arduino micro-controller can be used in education. Students can easily connect the sensor to the Arduino and collect three-component magnetic field data. Experiments can easily be turned into long-term monitoring projects by connecting sensors to the internet and providing an Internet-of-Things interface to store and to display the data in near-real time. Low-cost sensors are generally much noisier than their research grade counterparts, but can still provide an opportunity for students to learn about fundamental concepts such as signal quality, sampling, averaging, and filtering and to gain hands-on, concrete experience with observations. Sensors can be placed at different locations and compared both qualitatively and quantitatively. For example, with an inexpensive magnetometer, students can examine diurnal magnetic field variations and look for magnetic storms. Magnetic field orientation can be calculated and compared to the predicted geomagnetic field orientation at a given location. Data can be stored in simple text files to facilitate analysis with any convenient package. We illustrate the idea using Python notebooks, allowing students to explore the data interactively and to learn the basic principles of programming and reproducible research. Using an Arduino encourages students to interact with open-source data collection hardware and to experiment with ways to quickly, cheaply, and effectively measure the environment. Analysis of these data can lead to a deeper understanding of both geoscience and data processing.

  18. Development of a Low Cost MQL Setup for Turning Operations

    Directory of Open Access Journals (Sweden)

    Islam Sumaiya

    2017-01-01

    Full Text Available In this study, the effect of MQL application on the tool wear, surface roughness and chip formation in turning Aluminum alloy 6061 is investigated. Experiments were carried out by plain turning of an Aluminum bar with varying depth of cut, cutting speeds (spindle speed and cutting environments (Dry, Wet and MQL. A newly designed, cost efficient and portable MQL setup was developed for this study. For each experimental trial, five passes were carried out in order to promote the formation of tool wear. After each pass, the tool surface was examined under a microscope and the surface roughness was measured using a stylus based surface tester. The extent of tool wear from each pass is measured by using ImageJ software. Chips were collected after the five passes and were physically examined. The newly designed MQL delivery system was successful in delivering a fine mist of lubricant at the cutting point. MQL lubrication provided lower surface roughness and tool wear values compared to wet and dry conditions due to effective temperature reduction and improved lubrication penetration of cutting zones, as well as better chip flushing. Chip formed under MQL conditions had reduced chip thickness due to reduced temperatures. MQL was found to have the greatest positive impact on tool wear and surface roughness parameters based on ANOVA results.

  19. Production low cost plastic scintillator by using commercial polystyrene

    International Nuclear Information System (INIS)

    2011-01-01

    Plastic Scintillators can be described as solid materials which contain organic fluorescent compounds dissolved within a polymer matrix. Transparent plastics commonly used for light scintillation are Polystyrene (or PS, poly-vinyl-benzene) and polyvinyl-toluene (or PVT, poly-methyl-styron). By changing the composition of plastic Scintillators some features such as light yield, radiation hardening, decay time etc. can be controlled. Plastic scintillation detectors have been used in nuclear and high energy physics for many decades. Among their benefits are fast response, ease of manufacture and versatility. Their main drawbacks are radiation resistance and cost. Many research projects have concentrated on improving the fundamental properties of plastic scintillators, but little attention has focussed on their cost and easier manufacturing techniques. First plastic Scintillators were produced in 1950's. Activities for production of low cost Scintillators accelerated in second half of 1970's. In 1975 acrylic based Plexipop Scintillator was developed. Despite its low cost, since its structure was not aromatic the light yield of Plexipop was about one quarter of classical Scintillators. Problems arising from slow response time and weak mechanical properties in scintillators developed, has not been solved until 1980. Within the last decade extrusion method became very popular in preparation of low cost and high quality plastic scintillators. In this activity, preliminary studies for low cost plastic scintillator production by using commercial polystyrene pellets and extrusion plus compression method were aimed. For this purpose, PS blocks consist of commercial fluorescent dopant were prepared in June 2008 by use of the extruder and pres in SANAEM. Molds suitable for accoupling to extruder were designed and manufactured and optimum production parameters such as extrusion temperature profile, extrusion rate and moulding pressure were obtained hence, PS Scintillator Blocks

  20. Indoor Temperatures in Low Cost Housing in Johannesburg, South Africa

    Directory of Open Access Journals (Sweden)

    Nisha Naicker

    2017-11-01

    Full Text Available Ambient and indoor temperature affects thermal comfort and human health. In a changing climate with a predicted change in temperature extremes, understanding indoor temperatures, both hot and cold, of different housing types is important. This study aimed to assess the hourly, daily and monthly variation in indoor temperatures in different housing types, namely formal houses, informal houses, flats, government-built low-cost houses and old, apartheid era low-cost housing, in five impoverished urban communities in Johannesburg, South Africa. During the cross-sectional survey of the Health, Environment and Development study data loggers were installed in 100 homes (20 per suburb from February to May 2014. Indoor temperature and relative humidity were recorded on an hourly basis. Ambient outdoor temperatures were obtained from the nearest weather station. Indoor and outdoor temperature and relative humidity levels were compared; and an inter-comparison between the different housing types were also made. Apparent temperature was calculated to assess indoor thermal comfort. Data from 59 retrieved loggers showed a significant difference in monthly mean indoor temperature between the five different housing types (p < 0.0001. Low cost government-built houses and informal settlement houses had the greatest variation in temperature and experienced temperatures between 4 and 5 °C warmer than outdoor temperatures. Housing types occupied by poor communities experienced indoor temperature fluctuations often greater than that observed for ambient temperatures. Families living in government-built low-cost and informally-constructed homes are the most at risk for indoor temperature extremes. These types of housing should be prioritised for interventions aimed at assisting families to cope with extreme temperatures, gaining optimal thermal comfort and preventing temperature-related health effects.

  1. Sources and Transportation of Bulk, Low-Cost Lunar Simulant Materials

    Science.gov (United States)

    Rickman, D. L.

    2013-01-01

    Marshall Space Flight Center (MSFC) has built the Lunar Surface Testbed using 200 tons of volcanic cinder and ash from the same source used for the simulant series JSC-1. This Technical Memorandum examines the alternatives examined for transportation and source. The cost of low-cost lunar simulant is driven by the cost of transportation, which is controlled by distance and, to a lesser extent, quantity. Metabasalts in the eastern United States were evaluated due to their proximity to MSFC. Volcanic cinder deposits in New Mexico, Colorado, and Arizona were recognized as preferred sources. In addition to having fewer green, secondary minerals, they contain vesicular glass, both of which are desirable. Transportation costs were more than 90% of the total procurement costs for the simulant material.

  2. Comprehensive low-cost reliability centered maintenance. Final report

    International Nuclear Information System (INIS)

    Rotton, S.J.; Dozier, I.J.; Thow, R.

    1995-09-01

    Reliability Centered Maintenance (RCM) is a maintenance optimization approach that all electric utilities can apply to power plant systems. The Electric Power Research Institute and PECO Energy Company jointly sponsored this Comprehensive Low-Cost Reliability Centered Maintenance project to demonstrate that the standard RCM methodology could be streamlined to reduce the cost of analysis while maintaining a high quality product. EPRI's previous investigation of streamlined RCM methods being pioneered in the nuclear industry indicated that PECO Energy could expect to optimize its maintenance program at reduced cost by carefully controlling the scope without sacrificing documentation or technical quality. Using the insights obtained from these previous studies, three methods were defined in this project and were demonstrated in a large scale application to 60 systems at both the Limerick Generating Station and the Peach Bottom Atomic Power Station

  3. Low-cost, smartphone based frequency doubling technology visual field testing using virtual reality (Conference Presentation)

    Science.gov (United States)

    Alawa, Karam A.; Sayed, Mohamed; Arboleda, Alejandro; Durkee, Heather A.; Aguilar, Mariela C.; Lee, Richard K.

    2017-02-01

    Glaucoma is the leading cause of irreversible blindness worldwide. Due to its wide prevalence, effective screening tools are necessary. The purpose of this project is to design and evaluate a system that enables portable, cost effective, smartphone based visual field screening based on frequency doubling technology. The system is comprised of an Android smartphone to display frequency doubling stimuli and handle processing, a Bluetooth remote for user input, and a virtual reality headset to simulate the exam. The LG Nexus 5 smartphone and BoboVR Z3 virtual reality headset were used for their screen size and lens configuration, respectively. The system is capable of running the C-20, N-30, 24-2, and 30-2 testing patterns. Unlike the existing system, the smartphone FDT tests both eyes concurrently by showing the same background to both eyes but only displaying the stimulus to one eye at a time. Both the Humphrey Zeiss FDT and the smartphone FDT were tested on five subjects without a history of ocular disease with the C-20 testing pattern. The smartphone FDT successfully produced frequency doubling stimuli at the correct spatial and temporal frequency. Subjects could not tell which eye was being tested. All five subjects preferred the smartphone FDT to the Humphrey Zeiss FDT due to comfort and ease of use. The smartphone FDT is a low-cost, portable visual field screening device that can be used as a screening tool for glaucoma.

  4. A Low-Cost Fluorescent Sensor for pCO2 Measurements

    Directory of Open Access Journals (Sweden)

    Xudong Ge

    2014-04-01

    Full Text Available Global warming is believed to be caused by increasing amounts of greenhouse gases (mostly CO2 discharged into the environment by human activity. In addition to an increase in environmental temperature, an increased CO2 level has also led to ocean acidification. Ocean acidification and rising temperatures have disrupted the water’s ecological balance, killing off some plant and animal species, while encouraging the overgrowth of others. To minimize the effect of global warming on local ecosystem, there is a strong need to implement ocean observing systems to monitor the effects of anthropogenic CO2 and the impacts thereof on ocean biological productivity. Here, we describe the development of a low-cost fluorescent sensor for pCO2 measurements. The detector was exclusively assembled with low-cost optics and electronics, so that it would be affordable enough to be deployed in great numbers. The system has several novel features, such as an ideal 90° separation between excitation and emission, a beam combiner, a reference photodetector, etc. Initial tests showed that the system was stable and could achieve a high resolution despite the low cost.

  5. Application of low-cost adsorbents for dye removal--a review.

    Science.gov (United States)

    Gupta, V K; Suhas

    2009-06-01

    Dyes are an important class of pollutants, and can even be identified by the human eye. Disposal of dyes in precious water resources must be avoided, however, and for that various treatment technologies are in use. Among various methods adsorption occupies a prominent place in dye removal. The growing demand for efficient and low-cost treatment methods and the importance of adsorption has given rise to low-cost alternative adsorbents (LCAs). This review highlights and provides an overview of these LCAs comprising natural, industrial as well as synthetic materials/wastes and their application for dyes removal. In addition, various other methods used for dye removal from water and wastewater are also complied in brief. From a comprehensive literature review, it was found that some LCAs, in addition to having wide availability, have fast kinetics and appreciable adsorption capacities too. Advantages and disadvantages of adsorbents, favourable conditions for particular adsorbate-adsorbent systems, and adsorption capacities of various low-cost adsorbents and commercial activated carbons as available in the literature are presented. Conclusions have been drawn from the literature reviewed, and suggestions for future research are proposed.

  6. Examining the Influence of Cost Concern and Awareness of Low-cost Health Care on Cancer Screening among the Medically Underserved.

    Science.gov (United States)

    Best, Alicia L; Strane, Alcha; Christie, Omari; Bynum, Shalanda; Wiltshire, Jaqueline

    2017-01-01

    African Americans suffer a greater burden of mortality from breast, cervical, and colorectal cancers than other groups in the United States. Early detection through timely screening can improve survival outcomes; however, cost is frequently reported as a barrier to screening. Federally qualified health centers (FQHCs) provide preventive and primary care to underserved populations regardless of ability to pay, positioning them to improve cancer screening rates. The purpose of this study was to examine the influence of concern about health care cost (cost concern) and awareness of low-cost health care (awareness) on cancer screening among 236 African Americans within an FQHC service area using self-report surveys. Multiple logistic regression indicated that awareness was positively associated with cervical and colorectal cancer screening, while cost concern was negatively associated with mammography screening. Results indicate that improving awareness and understanding of low-cost health care could increase cancer screening among underserved African Americans.

  7. End-user perspective of low-cost sensors for outdoor air pollution monitoring

    OpenAIRE

    Rai, Aakash C.; Kumar, Prashant; Pilla, Francesco; Skouloudis, Andreas N.; Di Sabatino, Silvana; Ratti, Carlo; Yasar, Ansar; Rickerby, David

    2017-01-01

    Low-cost sensor technology can potentially revolutionise the area of air pollution monitoring by providing high-density spatiotemporal pollution data. Such data can be utilised for supplementing traditional pollution monitoring, improving exposure estimates, and raising community awareness about air pollution. However, data quality remains a major concern that hinders the widespread adoption of low-cost sensor technology. Unreliable data may mislead unsuspecting users and potentially lead to ...

  8. Epidemiological and Economic Impact of Monovalent and Pentavalent Rotavirus Vaccines in Low and Middle Income Countries: A Cost-effectiveness Modeling Analysis.

    Science.gov (United States)

    Paternina-Caicedo, Angel; De la Hoz-Restrepo, Fernando; Alvis-Guzmán, Nelson

    2015-07-01

    The competing choices of vaccination with either RV1 or RV5, the potential budget impact of vaccines on the EPI with different prices and new evidence make important an updated analysis for health decision makers in each country. The objective of this study is to assess cost-effectiveness of the monovalent and pentavalent rotavirus vaccines and impact on children deaths, inpatient and outpatient visits in 116 low and middle income countries that represent approximately 99% of rotavirus mortality. A decision tree model followed hypothetical cohorts of children from birth up to 5 years of age for each country in 2010. Inputs were gathered from international databases and previous research on incidence and effectiveness of monovalent and pentavalent vaccines. Costs were expressed in 2010 international dollars. Outcomes were reported in terms of cost per disability-adjusted life-year averted, comparing no vaccination with either monovalent or pentavalent mass introduction. Vaccine price was assumed fixed for all world low-income and middle-income countries. Around 292,000 deaths, 3.34 million inpatient cases and 23.09 million outpatient cases would occur with no vaccination. In the base-case scenario, monovalent vaccination would prevent 54.7% of inpatient cases and 45.4% of deaths. Pentavalent vaccination would prevent 51.4% of inpatient cases and 41.1% of deaths. The vaccine was cost-effective in all world countries in the base-case scenario for both vaccines. Cost per disability-adjusted life-year averted in all selected countries was I$372 for monovalent, and I$453 for pentavalent vaccination. Rotavirus vaccine is cost-effective in most analyzed countries. Despite cost-effectiveness analysis is a useful tool for decision making in middle-income countries, for low-income countries health decision makers should also assess the impact of introducing either vaccine on local resources and budget impact analysis of vaccination.

  9. Low-Cost High-Performance MRI

    Science.gov (United States)

    Sarracanie, Mathieu; Lapierre, Cristen D.; Salameh, Najat; Waddington, David E. J.; Witzel, Thomas; Rosen, Matthew S.

    2015-10-01

    Magnetic Resonance Imaging (MRI) is unparalleled in its ability to visualize anatomical structure and function non-invasively with high spatial and temporal resolution. Yet to overcome the low sensitivity inherent in inductive detection of weakly polarized nuclear spins, the vast majority of clinical MRI scanners employ superconducting magnets producing very high magnetic fields. Commonly found at 1.5-3 tesla (T), these powerful magnets are massive and have very strict infrastructure demands that preclude operation in many environments. MRI scanners are costly to purchase, site, and maintain, with the purchase price approaching $1 M per tesla (T) of magnetic field. We present here a remarkably simple, non-cryogenic approach to high-performance human MRI at ultra-low magnetic field, whereby modern under-sampling strategies are combined with fully-refocused dynamic spin control using steady-state free precession techniques. At 6.5 mT (more than 450 times lower than clinical MRI scanners) we demonstrate (2.5 × 3.5 × 8.5) mm3 imaging resolution in the living human brain using a simple, open-geometry electromagnet, with 3D image acquisition over the entire brain in 6 minutes. We contend that these practical ultra-low magnetic field implementations of MRI (standards for affordable (<$50,000) and robust portable devices.

  10. Low cost bare-plate solar air collector

    Science.gov (United States)

    Maag, W. L.; Wenzler, C. J.; Rom, F. E.; Vanarsdale, D. R.

    1980-09-01

    A low cost, bare plate solar collector for preheating ambient air was developed. This type of solar heating system would be applicable for preheating ventilation air for public buildings or other commercial and industrial ventilation requirements. Two prototype collectors were designed, fabricated and installed into an instrumented test system. Tests were conducted for a period of five months. Results of the tests showed consistent operating efficiencies of 60 percent or greater with air preheat temperature uses up to 20 degrees for one of the prototypes. The economic analyses indicated that this type of solar system was economically viable. For the materials of construction and the type of fabrication and installation perceived, costs for the bare plate solar collector are attainable. Applications for preheating ventilation air for schools were evaluated and judged to be economically viable.

  11. Ultra-low-power and ultra-low-cost short-range wireless receivers in nanoscale CMOS

    CERN Document Server

    Lin, Zhicheng; Martins, Rui Paulo

    2016-01-01

    This book provides readers with a description of state-of-the-art techniques to be used for ultra-low-power (ULP) and ultra-low-cost (ULC), short-range wireless receivers. Readers will learn what is required to deploy these receivers in short-range wireless sensor networks, which are proliferating widely to serve the internet of things (IoT) for “smart cities.” The authors address key challenges involved with the technology and the typical tradeoffs between ULP and ULC. Three design examples with advanced circuit techniques are described in order to address these trade-offs, which specially focus on cost minimization. These three techniques enable respectively, cascading of radio frequency (RF) and baseband (BB) circuits under an ultra-low-voltage (ULV) supply, cascoding of RF and BB circuits in current domain for current reuse, and a novel function-reuse receiver architecture, suitable for ULV and multi-band ULP applications such as the sub-GHz ZigBee. ·         Summarizes the state-of-the-art i...

  12. A low-cost electrically pulsed shower detector

    CERN Document Server

    Conversi, M; Gentile, S; Nardi, M

    1976-01-01

    A sampling total absorption detector characterized by an extremely low cost and providing also identification of particle tracks has been developed. Preliminary results on the performance of a model with 14 radiation lengths, exposed to electrons of energies E up to 4 GeV, show that this instrument can measure the primary electron energy with an accuracy (r.m.s.) $\\Delta E/E= \\pm(12 $%) / $\\sqrt E$ (E in GeV).

  13. Towards a Low-Cost Quadrotor Research Platform

    Science.gov (United States)

    2010-03-01

    FIGURES Figure 1. Quadrotor schematic showing rotor direction of rotation (From [2])................3 Figure 2. Toy quadrotor: Walkera UFO (from...Some examples are the Walkera UFO #5, Walkera UFO #8, Dragonfly, and Alien Air Jump Jet. Figure 2. Toy quadrotor: Walkera UFO (from Walkera...the X- UFO made by Silverlit Electronics used small mechanical gyros. These were relatively cheap due to low-cost labor, but suffered from mechanical

  14. IQ-Station: A Low Cost Portable Immersive Environment

    Energy Technology Data Exchange (ETDEWEB)

    Eric Whiting; Patrick O' Leary; William Sherman; Eric Wernert

    2010-11-01

    The emergence of inexpensive 3D TV’s, affordable input and rendering hardware and open-source software has created a yeasty atmosphere for the development of low-cost immersive environments (IE). A low cost IE system, or IQ-station, fashioned from commercial off the shelf technology (COTS), coupled with a targeted immersive application can be a viable laboratory instrument for enhancing scientific workflow for exploration and analysis. The use of an IQ-station in a laboratory setting also has the potential of quickening the adoption of a more sophisticated immersive environment as a critical enabler in modern scientific and engineering workflows. Prior work in immersive environments generally required either a head mounted display (HMD) system or a large projector-based implementation both of which have limitations in terms of cost, usability, or space requirements. The solution presented here provides an alternative platform providing a reasonable immersive experience that addresses those limitations. Our work brings together the needed hardware and software to create a fully integrated immersive display and interface system that can be readily deployed in laboratories and common workspaces. By doing so, it is now feasible for immersive technologies to be included in researchers’ day-to-day workflows. The IQ-Station sets the stage for much wider adoption of immersive environments outside the small communities of virtual reality centers.

  15. A low cost rapid prototype platform for a three phase PFC rectifier application

    DEFF Research Database (Denmark)

    Haase, Frerk; Kouchaki, Alireza; Nymand, Morten

    2015-01-01

    In this paper the design and development of a low cost rapid prototype platform for a Three Phase PFC rectifier application is presented. The active rectifier consists of a SiC-MOSFET based PWM converter and a low cost rapid prototype platform for simulating and implementing the digital control...

  16. Electrochemistry-based approaches to low cost, high sensitivity, automated, multiplexed protein immunoassays for cancer diagnostics.

    Science.gov (United States)

    Dixit, Chandra K; Kadimisetty, Karteek; Otieno, Brunah A; Tang, Chi; Malla, Spundana; Krause, Colleen E; Rusling, James F

    2016-01-21

    Early detection and reliable diagnostics are keys to effectively design cancer therapies with better prognoses. The simultaneous detection of panels of biomarker proteins holds great promise as a general tool for reliable cancer diagnostics. A major challenge in designing such a panel is to decide upon a coherent group of biomarkers which have higher specificity for a given type of cancer. The second big challenge is to develop test devices to measure these biomarkers quantitatively with high sensitivity and specificity, such that there are no interferences from the complex serum or tissue matrices. Lastly, integrating all these tests into a technology that does not require exclusive training to operate, and can be used at point-of-care (POC) is another potential bottleneck in futuristic cancer diagnostics. In this article, we review electrochemistry-based tools and technologies developed and/or used in our laboratories to construct low-cost microfluidic protein arrays for the highly sensitive detection of a panel of cancer-specific biomarkers with high specificity which at the same time has the potential to be translated into POC applications.

  17. Regional Energy Planning Tool for Renewable Integrated Low-Energy District Heating Systems

    DEFF Research Database (Denmark)

    Tol, Hakan; Dincer, Ibrahim; Svendsen, Svend

    2013-01-01

    Low-energy district heating systems, operating at low temperature of 55 °C as supply and 25°C as return, can be the energy solution as being the prevailing heating infrastructure in urban areas, considering future energy schemesaiming at increased exploitation of renewable energy sources together...... with low-energy houses in focus with intensified energy efficiency measures. Employing low-temperature operation allows the ease to exploit not only any type of heat source but also low-grade sources, i.e., renewable and industrial waste heat, which would otherwise be lost. In this chapter, a regional...... energy planning tool is described considered with various energy conversion systems based on renewable energy sources to be supplied to an integrated energy infrastructure involving a low-energy district heating, a district cooling, and an electricity grid. The developed tool is performed for two case...

  18. Fast-track, low-cost construction starts with the owner

    International Nuclear Information System (INIS)

    Smock, R.

    1992-01-01

    As we approach the threshold of a new round of ordering of base load generating capacity after a 15-year hiatus, power pant owners are taking a long, hard look at construction. The last round of base load construction was plagued with construction cost overruns and delays. Billions of dollars in cost overruns, many attributable to construction delays, were not allowed to be placed in utilities' rate bases. Those problems will not be tolerated in the next round. During the past few years the construction climate has changed. Non-utility power producers have demonstrated and ability to build small power plants-including many steam plants burning solid fuels-quickly and at surprisingly low costs. In this paper the cost-plus approach traditionally taken by more utilities, who will lead in the base-load construction phase, is being seriously questioned

  19. Automated Low-Cost Smartphone-Based Lateral Flow Saliva Test Reader for Drugs-of-Abuse Detection

    Directory of Open Access Journals (Sweden)

    Adrian Carrio

    2015-11-01

    Full Text Available Lateral flow assay tests are nowadays becoming powerful, low-cost diagnostic tools. Obtaining a result is usually subject to visual interpretation of colored areas on the test by a human operator, introducing subjectivity and the possibility of errors in the extraction of the results. While automated test readers providing a result-consistent solution are widely available, they usually lack portability. In this paper, we present a smartphone-based automated reader for drug-of-abuse lateral flow assay tests, consisting of an inexpensive light box and a smartphone device. Test images captured with the smartphone camera are processed in the device using computer vision and machine learning techniques to perform automatic extraction of the results. A deep validation of the system has been carried out showing the high accuracy of the system. The proposed approach, applicable to any line-based or color-based lateral flow test in the market, effectively reduces the manufacturing costs of the reader and makes it portable and massively available while providing accurate, reliable results.

  20. Automated Low-Cost Smartphone-Based Lateral Flow Saliva Test Reader for Drugs-of-Abuse Detection.

    Science.gov (United States)

    Carrio, Adrian; Sampedro, Carlos; Sanchez-Lopez, Jose Luis; Pimienta, Miguel; Campoy, Pascual

    2015-11-24

    Lateral flow assay tests are nowadays becoming powerful, low-cost diagnostic tools. Obtaining a result is usually subject to visual interpretation of colored areas on the test by a human operator, introducing subjectivity and the possibility of errors in the extraction of the results. While automated test readers providing a result-consistent solution are widely available, they usually lack portability. In this paper, we present a smartphone-based automated reader for drug-of-abuse lateral flow assay tests, consisting of an inexpensive light box and a smartphone device. Test images captured with the smartphone camera are processed in the device using computer vision and machine learning techniques to perform automatic extraction of the results. A deep validation of the system has been carried out showing the high accuracy of the system. The proposed approach, applicable to any line-based or color-based lateral flow test in the market, effectively reduces the manufacturing costs of the reader and makes it portable and massively available while providing accurate, reliable results.

  1. Low-cost storage options for solar hydrogen systems for remote area power supply

    International Nuclear Information System (INIS)

    Suhaib Muhammad Ali; John Andrews

    2006-01-01

    Equipment for storing hydrogen gas under pressure typically accounts for a significant proportion of the total capital cost of solar-hydrogen systems for remote area power supply (RAPS). RAPS remain a potential early market for renewable energy - hydrogen systems because of the relatively high costs of conventional energy sources in remote regions. In the present paper the storage requirements of PV-based solar-hydrogen RAPS systems employing PEM electrolysers and fuel cells to meet a range of typical remote area daily and annual demand profiles are investigated using a spread sheet-based simulation model. It is found that as the costs of storage are lowered the requirement for longer-term storage from summer to winter is increased with consequent potential gains in the overall economics of the solar-hydrogen system. In many remote applications, there is ample space for hydrogen storages with relatively large volumes. Hence it may be most cost-effective to store hydrogen at low to medium pressures achievable by using PEM electrolysers directly to generate the hydrogen at the pressures required, without a requirement for separate electrically-driven compressors. The latter add to system costs while requiring significant parasitic electricity consumption. Experimental investigations into a number of low-cost storage options including plastic tanks and low-to-medium pressure metal and composite cylinders are reported. On the basis of these findings, the economics of solar-hydrogen RAPS systems employing large-volume low-cost storage are investigated. (authors)

  2. Activity-based costing methodology as tool for costing in hematopathology laboratory.

    Science.gov (United States)

    Gujral, Sumeet; Dongre, Kanchan; Bhindare, Sonal; Subramanian, P G; Narayan, Hkv; Mahajan, Asim; Batura, Rekha; Hingnekar, Chitra; Chabbria, Meenu; Nair, C N

    2010-01-01

    Cost analysis in laboratories represents a necessary phase in their scientific progression. To calculate indirect cost and thus total cost per sample of various tests at Hematopathology laboratory (HPL). Activity-based costing (ABC) method is used to calculate per cost test of the hematopathology laboratory. Information is collected from registers, purchase orders, annual maintenance contracts (AMCs), payrolls, account books, hospital bills and registers along with informal interviews with hospital staff. Cost per test decreases as total number of samples increases. Maximum annual expense at the HPL is on reagents and consumables followed by manpower. Cost per test is higher for specialized tests which interpret morphological or flow data and are done by a pathologist. Despite several limitations and assumptions, this was an attempt to understand how the resources are consumed in a large size government-run laboratory. The rate structure needs to be revised for most of the tests, mainly for complete blood counts (CBC), bone marrow examination, coagulation tests and Immunophenotyping. This costing exercise is laboratory specific and each laboratory needs to do its own costing. Such an exercise may help a laboratory redesign its costing structure or at least understand the economics involved in the laboratory management.

  3. Low-cost evacuated-tube solar collector appendices. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Beecher, D.T.

    1980-05-31

    A low cost solar heat energy collector module and array has been designed using the evacuated tube, selective absorber, air cooled concept. Glass tubing as used in fluorescent lamps with automatic sealing methods is a key feature of the evacuated tube design. A molded fiber glass concentrating reflector panel and sheet metal header assembly are proposed. Major design problems involved included the cost of materials and labor, thermal expansion and distortion problems, high stagnation and operating temperatures, isolation, thermal efficiency, sealing, joining, air pressure drop, and weight of the preassembled module. A cost of less than $5 per active square foot of collecting surface has been estimated for materials and labor of the module and its mounting frame.

  4. Cost of common low back pain and lumbar radiculopathy in rheumatologic consultation in Lomé.

    Science.gov (United States)

    Fianyo, Eyram; Oniankitan, Owonayo; Tagbor Komi, C; Kakpovi, Kodjo; Houzou, Prénam; Koffi-Tessio Viwalé, E S; Mijiyawa, Moustafa

    2017-03-01

    The cost of low back pain was the subject of few studies in black Africa. To assess the cost of common low back pain and lumbar radiculopathy in Lomé. A six months study was realised in the rheumatologic department of CHU Sylvanus Olympio. 103 consecutive patients suffering from a common low back pain or lumbar radiculopathy were included. To assess direct, indirect and non-financial costs they were questioned about their expense during the year. Financial cost of common low back pain and lumbar radiculopathy amounted to 107.2 $ US (extremes: 5.8 and 726.1 $ US). This amount, quadruple of guaranteed minimum wage, felled under two headings: direct cost (56.3 $ US; 53% of total sum), indirect cost (50.3 $ US; 47% of total sum). Non-financial cost were: disruption in daily activities (94%), impact in emotional and sexual life (59%), impact on the family's budget (69%), abandon of family's projects (58%) or of leisure (42%). In black Africa top priority is given to the fight against infectious diseases those cause an important mortality. But common low back pain and lumbar radiculopathy, those have social and economic impact, should be given more attention.

  5. Two novel approaches used to produce biodiesel from low-cost feedstocks

    Energy Technology Data Exchange (ETDEWEB)

    Fan, X.; Chen, F. [Clemson Univ., SC (United States). Dept. of Food Science and Human Nutrition; Wang, X. [Clemson Univ., SC (United States). Dept. of Genetics and Biochemistry

    2010-07-01

    The cost of feedstock has a significant effect of the economic viability of biodiesel production. The paper discussed a preliminary study looking at 2 approaches used to economically produce biodiesel, one from waste cooking oil (WCO) and the other from flaked cottonseed. Ultrasound-assisted synthesis was used to produce biodiesel from WCO, and in situ transesterification was used to produce biodiesel from the flaked cottonseed. The use of WCO solves the problem of waste disposal and also generates an environmentally benign fuel while at the same time lowering the costs involved in producing biodiesel. Ultrasonification has proven to be an efficient, low-cost, energy saving means of producing biodiesel. In situ transesterification makes solvent extraction and oil cleanup prior to biodiesel synthesis unnecessary, thereby simplifying the reaction steps. Based on the results of gas chromatography and high-performance liquid chromatography tests, both approaches are feasible for the production of biodiesel from low-cost feedstock. 15 refs., 4 figs.

  6. A Low Cost and High Speed Electrical Capacitance Tomography System Design

    Directory of Open Access Journals (Sweden)

    Ruzairi ABDUL RAHIM

    2010-03-01

    Full Text Available Electrical capacitance tomography system is a system which can be used for imaging industrial multi-component processes involving non-conducting fluids in pipelines. In order to make an ECT system applicable in all kinds of industries, the cost factor of building an ECT system is essential. In this research, we focus on reducing the cost of the system while not affecting the quality of the results. In the past, most of the researches in tomography system have concentrated more on the design of the sensor, and use DAS card as the interface to the PC. This will increase the cost of the system. In this case, the cost of the data acquisition system will be needed to be taken into consideration. To develop a low cost and fast data acquisition system, a Universal Serial Bus (USB is found to be the most ideal technology. In order to further reduce the cost of the ECT system, a very low cost material, aluminium plates are used as the electrodes of the system. The information obtained in the PC will be reconstructed using iterative algorithm in order to obtain a precise image of the flow in the pipeline. The information obtained from the system will be useful for the purpose of controlling the flow in the pipeline.

  7. Reconstruction of 3D tree stem models from low-cost terrestrial laser scanner data

    Science.gov (United States)

    Kelbe, Dave; Romanczyk, Paul; van Aardt, Jan; Cawse-Nicholson, Kerry

    2013-05-01

    With the development of increasingly advanced airborne sensing systems, there is a growing need to support sensor system design, modeling, and product-algorithm development with explicit 3D structural ground truth commensurate to the scale of acquisition. Terrestrial laser scanning is one such technique which could provide this structural information. Commercial instrumentation to suit this purpose has existed for some time now, but cost can be a prohibitive barrier for some applications. As such we recently developed a unique laser scanning system from readily-available components, supporting low cost, highly portable, and rapid measurement of below-canopy 3D forest structure. Tools were developed to automatically reconstruct tree stem models as an initial step towards virtual forest scene generation. The objective of this paper is to assess the potential of this hardware/algorithm suite to reconstruct 3D stem information for a single scan of a New England hardwood forest site. Detailed tree stem structure (e.g., taper, sweep, and lean) is recovered for trees of varying diameter, species, and range from the sensor. Absolute stem diameter retrieval accuracy is 12.5%, with a 4.5% overestimation bias likely due to the LiDAR beam divergence.

  8. Activity-based costing methodology as tool for costing in hematopathology laboratory

    Directory of Open Access Journals (Sweden)

    Gujral Sumeet

    2010-01-01

    Full Text Available Background: Cost analysis in laboratories represents a necessary phase in their scientific progression. Aim: To calculate indirect cost and thus total cost per sample of various tests at Hematopathology laboratory (HPL Settings and Design: Activity-based costing (ABC method is used to calculate per cost test of the hematopathology laboratory. Material and Methods: Information is collected from registers, purchase orders, annual maintenance contracts (AMCs, payrolls, account books, hospital bills and registers along with informal interviews with hospital staff. Results: Cost per test decreases as total number of samples increases. Maximum annual expense at the HPL is on reagents and consumables followed by manpower. Cost per test is higher for specialized tests which interpret morphological or flow data and are done by a pathologist. Conclusions: Despite several limitations and assumptions, this was an attempt to understand how the resources are consumed in a large size government-run laboratory. The rate structure needs to be revised for most of the tests, mainly for complete blood counts (CBC, bone marrow examination, coagulation tests and Immunophenotyping. This costing exercise is laboratory specific and each laboratory needs to do its own costing. Such an exercise may help a laboratory redesign its costing structure or at least understand the economics involved in the laboratory management.

  9. Trends and variation in prescribing of low-priority treatments identified by NHS England: a cross-sectional study and interactive data tool in English primary care.

    Science.gov (United States)

    Walker, Alex J; Curtis, Helen J; Bacon, Seb; Croker, Richard; Goldacre, Ben

    2018-06-01

    Objectives NHS England recently announced a consultation seeking to discourage the use of treatments it considers to be low-value. We set out to produce an interactive data resource to show savings in each NHS general practice and to assess the current use of these treatments, their change in use over time, and the extent and reasons for variation in such prescribing. Design Cross-sectional analysis. Setting English primary care. Participants English general practices. Main outcome measures We determined the cost per 1000 patients for prescribing of each of 18 treatments identified by NHS England for each month from July 2012 to June 2017, and also aggregated over the most recent year to assess total cost and variation among practices. We used mixed effects linear regression to determine factors associated with cost of prescribing. Results Spend on low-value treatments was £153.5 m in the last year, across 5.8 m prescriptions (mean, £26 per prescription). Among individual treatments, liothyronine had the highest prescribing cost at £29.6 m, followed by trimipramine (£20.2 m). Over time, the overall total number of low-value prescriptions decreased, but the cost increased, although this varied greatly between treatments. Three treatment areas increased in cost and two increased in volume, all others reduced in cost and volume. Annual practice level spending varied widely (median, £2262 per thousand patients; interquartile range £1439 to £3298). Proportion of patients over 65 was strongly associated with low-value prescribing, as was Clinical Commissioning Group. Our interactive data tool was deployed to OpenPrescribing.net where monthly updated figures and graphs can be viewed. Conclusions Prescribing of low-value treatments is extensive but varies widely by treatment, geographic area and individual practice. Despite a fall in prescription numbers, the overall cost of prescribing for low-value items has risen. Prescribing behaviour is clustered by

  10. Decision-Making Tool for Cost-Efficient and Environmentally Friendly Wood Mobilisation

    Directory of Open Access Journals (Sweden)

    Matevž Triplat

    2015-06-01

    Full Text Available Background and Purpose: With development of forest management technologies, the efficiency of wood production was significantly improved, and thus the impact on forests has changed as well. The article presents a practical decision-making tool for selection of most suitable harvesting system, considering given terrain as well as expected soil conditions on harvesting sites. The decision-making tool should support cost-efficient and environmentally friendly mobilisation of wood. Materials and Methods: The presented decision-making tool is based on ground bearing capacities (relevant environmental parameter and nominal ground pressure (harvesting system characteristics. Soil and terrain (slope characteristics were taken into account for selection of the most suitable harvesting system. Three-step methodological approach was suggested, where soil and terrain conditions were defined in first step, while harvesting system were described using wood process charts (“functiogramms” in second step. In final step ecological and technological requirements were matched. Results: To exemplify the three-step methodology, a decision-making tool was prepared for the three selected harvesting systems. The proposed harvesting systems differ in technological, ecological and economic aspects, but each is limited by at least one of the aspect. Conclusions: The decision-making tool in combination with the presented wood process charts (“functiogramms” can simplify and facilitate forest production planning, although it can also be used in case of unforeseen event e.g. changing of soil moisture, machinery failure and insufficient current capacities. Considering the envisaged quantities and types of forest wooden assortments, it is possible to use the decision-making tool for a basic selection of most appropriate harvesting systems. The main idea behind the suggested three step methodological approach is that forest workers can prepare individual decision

  11. OPV for mobile applications: an evaluation of roll-to-roll processed indium and silver free polymer solar cells through analysis of life cycle, cost and layer quality using inline optical and functional inspection tools

    DEFF Research Database (Denmark)

    Espinosa Martinez, Nieves; Lenzmann, Frank O.; Ryley, Stephen

    2013-01-01

    Organic photovoltaic modules have been evaluated for their integration in mobile electronic applications such as a laser pointer. An evaluation of roll-to-roll processed indium and silver free polymer solar cells has been carried out from different perspectives: life cycle assessment, cost analysis...... and layer quality evaluation using inline optical and functional inspection tools. The polymer solar cells were fabricated in credit card sized modules by three routes, and several encapsulation alternatives have been explored, with the aim to provide the simplest but functional protection against moisture...... a low carbon footprint. From the economic perspective there is a huge reduction in the cost of the ITO- and silver-free options, reaching as low as 0.25 V for the OPV module. We used inspection tools such as a roll-to-roll inspection system to evaluate all processing steps during the fabrication...

  12. Low-cost thermo-electric infrared FPAs and their automotive applications

    Science.gov (United States)

    Hirota, Masaki; Ohta, Yoshimi; Fukuyama, Yasuhiro

    2008-04-01

    This paper describes three low-cost infrared focal plane arrays (FPAs) having a 1,536, 2,304, and 10,800 elements and experimental vehicle systems. They have a low-cost potential because each element consists of p-n polysilicon thermocouples, which allows the use of low-cost ultra-fine microfabrication technology commonly employed in the conventional semiconductor manufacturing processes. To increase the responsivity of FPA, we have developed a precisely patterned Au-black absorber that has high infrared absorptivity of more than 90%. The FPA having a 2,304 elements achieved high resposivity of 4,300 V/W. In order to reduce package cost, we developed a vacuum-sealed package integrated with a molded ZnS lens. The camera aiming the temperature measurement of a passenger cabin is compact and light weight devices that measures 45 x 45 x 30 mm and weighs 190 g. The camera achieves a noise equivalent temperature deviation (NETD) of less than 0.7°C from 0 to 40°C. In this paper, we also present a several experimental systems that use infrared cameras. One experimental system is a blind spot pedestrian warning system that employs four infrared cameras. It can detect the infrared radiation emitted from a human body and alerts the driver when a pedestrian is in a blind spot. The system can also prevent the vehicle from moving in the direction of the pedestrian. Another system uses a visible-light camera and infrared sensors to detect the presence of a pedestrian in a rear blind spot and alerts the driver. The third system is a new type of human-machine interface system that enables the driver to control the car's audio system without letting go of the steering wheel. Uncooled infrared cameras are still costly, which limits their automotive use to high-end luxury cars at present. To promote widespread use of IR imaging sensors on vehicles, we need to reduce their cost further.

  13. Low-Cost alpha Alane for Hydrogen Storage

    Energy Technology Data Exchange (ETDEWEB)

    Fabian, Tibor [Ardica Technologies, San Francisco, CA (United States); Petrie, Mark [SRI International, Menlo Park, CA (United States); Crouch-Baker, Steven [SRI International, Menlo Park, CA (United States); Fong, Henry [SRI International, Menlo Park, CA (United States)

    2017-10-10

    This project was directed towards the further development of the Savannah River National Laboratory (SRNL) lab-scale electrochemical synthesis of the hydrogen storage material alpha-alane and Ardica Technologies-SRI International (SRI) chemical downstream processes that are necessary to meet DoE cost metrics and transition alpha-alane synthesis to an industrial scale. Ardica has demonstrated the use of alpha-alane in a fuel-cell system for the U.S. Army WFC20 20W soldier power system that has successfully passed initial field trials with individual soldiers. While alpha-alane has been clearly identified as a desirable hydrogen storage material, cost-effective means for its production and regeneration on a scale of use applicable to the industry have yet to be established. We focused on three, principal development areas: 1. The construction of a comprehensive engineering techno-economic model to establish the production costs of alpha-alane by both electrochemical and chemical routes at scale. 2. The identification of critical, cost-saving design elements of the electrochemical cell and the quantification of the product yields of the primary electrochemical process. A moving particle-bed reactor design was constructed and operated. 3. The experimental quantification of the product yields of candidate downstream chemical processes necessary to produce alpha-alane to complete the most cost-effective overall manufacturing process. Our techno-economic model shows that under key assumptions most 2015 and 2020 DOE hydrogen storage system cost targets for low and medium power can be achieved using the electrochemical alane synthesis process. To meet the most aggressive 2020 storage system cost target, $1/g, our model indicates that 420 metric tons per year (MT/y) production of alpha-alane is required. Laboratory-scale experimental work demonstrated that the yields of two of the three critical component steps within the overall “electrochemical process” were

  14. Advances in low-cost long-wave infrared polymer windows

    Science.gov (United States)

    Weimer, Wayne A.; Klocek, Paul

    1999-07-01

    Recent improvements in engineered polymeric material compositions and advances in processing methodologies developed and patented at Raytheon Systems Company have produced long wave IR windows at exceptionally low costs. These UV stabilized, high strength windows incorporating subwavelength structured antireflection surfaces are enabling IR imaging systems to penetrate commercial markets and will reduce the cost of systems delivered to the military. The optical and mechanical properties of these windows will be discussed in detail with reference to the short and long-term impact on military IR imaging systems.

  15. Shore protection structures along Kerala coast-low cost alteratives

    Digital Repository Service at National Institute of Oceanography (India)

    DineshKumar, P.K.; Jasanto, P.K.; Sankaranarayanan, V.N.

    Several studies over the last two decades on low cost shore protection measures are reviewed to have an integrated profile with a point on application to the sheltered coasts of Kerala. It is emphasised that these alternative are generally...

  16. Pathways toward a low cost evacuated collector system

    Science.gov (United States)

    Hull, J. R.; Schertz, W. W.; Allen, J. W.; Ogallagher, J. J.; Winston, R.

    The goal of widespread use of solar thermal collectors will only be achieved when they are proven to be economically superior to competing energy sources. Evacuated tubular collectors appear to have the potential to achieve this goal. An advanced evacuated collector using nonimaging concentration under development at the University of Chicago and Argonne can achieve a 50% seasonal efficiency at heat delivery temperatures in excess of 170C. The same collector has an optical efficiency so that low temperature performance is also excellent. In this advanced collector design all of the critical components are enclosed in the vacuum, and the collector has an inherently long lifetime. The current cost of evacuated systems is too high, mainly because the volume of production has been too low to realize economies of mass production. It appears that certain design features of evacuated collectors can be changed (e.g., use of heat pipe absorbers) so as to introduce new system design and market strategy options that can reduce the balance of system cost.

  17. Analysis of Anterior Cervical Discectomy and Fusion Healthcare Costs via the Value-Driven Outcomes Tool.

    Science.gov (United States)

    Reese, Jared C; Karsy, Michael; Twitchell, Spencer; Bisson, Erica F

    2018-04-11

    Examining the costs of single- and multilevel anterior cervical discectomy and fusion (ACDF) is important for the identification of cost drivers and potentially reducing patient costs. A novel tool at our institution provides direct costs for the identification of potential drivers. To assess perioperative healthcare costs for patients undergoing an ACDF. Patients who underwent an elective ACDF between July 2011 and January 2017 were identified retrospectively. Factors adding to total cost were placed into subcategories to identify the most significant contributors, and potential drivers of total cost were evaluated using a multivariable linear regression model. A total of 465 patients (mean, age 53 ± 12 yr, 54% male) met the inclusion criteria for this study. The distribution of total cost was broken down into supplies/implants (39%), facility utilization (37%), physician fees (14%), pharmacy (7%), imaging (2%), and laboratory studies (1%). A multivariable linear regression analysis showed that total cost was significantly affected by the number of levels operated on, operating room time, and length of stay. Costs also showed a narrow distribution with few outliers and did not vary significantly over time. These results suggest that facility utilization and supplies/implants are the predominant cost contributors, accounting for 76% of the total cost of ACDF procedures. Efforts at lowering costs within these categories should make the most impact on providing more cost-effective care.

  18. NeuroKinect: A Novel Low-Cost 3Dvideo-EEG System for Epileptic Seizure Motion Quantification.

    Directory of Open Access Journals (Sweden)

    João Paulo Silva Cunha

    Full Text Available Epilepsy is a common neurological disorder which affects 0.5-1% of the world population. Its diagnosis relies both on Electroencephalogram (EEG findings and characteristic seizure-induced body movements--called seizure semiology. Thus, synchronous EEG and (2Dvideo recording systems (known as Video-EEG are the most accurate tools for epilepsy diagnosis. Despite the establishment of several quantitative methods for EEG analysis, seizure semiology is still analyzed by visual inspection, based on epileptologists' subjective interpretation of the movements of interest (MOIs that occur during recorded seizures. In this contribution, we present NeuroKinect, a low-cost, easy to setup and operate solution for a novel 3Dvideo-EEG system. It is based on a RGB-D sensor (Microsoft Kinect camera and performs 24/7 monitoring of an Epilepsy Monitoring Unit (EMU bed. It does not require the attachment of any reflectors or sensors to the patient's body and has a very low maintenance load. To evaluate its performance and usability, we mounted a state-of-the-art 6-camera motion-capture system and our low-cost solution over the same EMU bed. A comparative study of seizure-simulated MOIs showed an average correlation of the resulting 3D motion trajectories of 84.2%. Then, we used our system on the routine of an EMU and collected 9 different seizures where we could perform 3D kinematic analysis of 42 MOIs arising from the temporal (TLE (n = 19 and extratemporal (ETE brain regions (n = 23. The obtained results showed that movement displacement and movement extent discriminated both seizure MOI groups with statistically significant levels (mean = 0.15 m vs. 0.44 m, p<0.001; mean = 0.068 m(3 vs. 0.14 m(3, p<0.05, respectively. Furthermore, TLE MOIs were significantly shorter than ETE (mean = 23 seconds vs 35 seconds, p<0.01 and presented higher jerking levels (mean = 345 ms(-3 vs 172 ms(-3, p<0.05. Our newly implemented 3D approach is faster by 87.5% in extracting body

  19. NeuroKinect: A Novel Low-Cost 3Dvideo-EEG System for Epileptic Seizure Motion Quantification.

    Science.gov (United States)

    Cunha, João Paulo Silva; Choupina, Hugo Miguel Pereira; Rocha, Ana Patrícia; Fernandes, José Maria; Achilles, Felix; Loesch, Anna Mira; Vollmar, Christian; Hartl, Elisabeth; Noachtar, Soheyl

    2016-01-01

    Epilepsy is a common neurological disorder which affects 0.5-1% of the world population. Its diagnosis relies both on Electroencephalogram (EEG) findings and characteristic seizure-induced body movements--called seizure semiology. Thus, synchronous EEG and (2D)video recording systems (known as Video-EEG) are the most accurate tools for epilepsy diagnosis. Despite the establishment of several quantitative methods for EEG analysis, seizure semiology is still analyzed by visual inspection, based on epileptologists' subjective interpretation of the movements of interest (MOIs) that occur during recorded seizures. In this contribution, we present NeuroKinect, a low-cost, easy to setup and operate solution for a novel 3Dvideo-EEG system. It is based on a RGB-D sensor (Microsoft Kinect camera) and performs 24/7 monitoring of an Epilepsy Monitoring Unit (EMU) bed. It does not require the attachment of any reflectors or sensors to the patient's body and has a very low maintenance load. To evaluate its performance and usability, we mounted a state-of-the-art 6-camera motion-capture system and our low-cost solution over the same EMU bed. A comparative study of seizure-simulated MOIs showed an average correlation of the resulting 3D motion trajectories of 84.2%. Then, we used our system on the routine of an EMU and collected 9 different seizures where we could perform 3D kinematic analysis of 42 MOIs arising from the temporal (TLE) (n = 19) and extratemporal (ETE) brain regions (n = 23). The obtained results showed that movement displacement and movement extent discriminated both seizure MOI groups with statistically significant levels (mean = 0.15 m vs. 0.44 m, p<0.001; mean = 0.068 m(3) vs. 0.14 m(3), p<0.05, respectively). Furthermore, TLE MOIs were significantly shorter than ETE (mean = 23 seconds vs 35 seconds, p<0.01) and presented higher jerking levels (mean = 345 ms(-3) vs 172 ms(-3), p<0.05). Our newly implemented 3D approach is faster by 87.5% in extracting body

  20. A simple low cost latent fingerprint sensor based on deflectometry and WFT analysis

    Science.gov (United States)

    Dhanotia, Jitendra; Chatterjee, Amit; Bhatia, Vimal; Prakash, Shashi

    2018-02-01

    In criminal investigations, latent fingerprints are one of the most significant forms of evidence and most commonly used forensic investigation tool worldwide. The existing non-contact latent fingerprint detection systems are bulky, expensive and require environment which is shock and vibration resistant, thereby limiting their usability outside the laboratory. In this article, a compact, full field, low cost technique for profiling of fingerprints using deflectometry is proposed. Using inexpensive mobile phone screen based structured illumination, and windowed Fourier transform (WFT) based phase retrieval mechanism, the 2D and 3D phase plots reconstruct the profile information of the fingerprint. The phase information is also used to confirm a match between two fingerprints in real time. Since the proposed technique is non-interferometric, the measurements are least affected by environmental perturbations. Using the proposed technique, a portable sensor capable of field deployment has been realized.

  1. Scalable Light Module for Low-Cost, High-Efficiency Light- Emitting Diode Luminaires

    Energy Technology Data Exchange (ETDEWEB)

    Tarsa, Eric [Cree, Inc., Goleta, CA (United States)

    2015-08-31

    During this two-year program Cree developed a scalable, modular optical architecture for low-cost, high-efficacy light emitting diode (LED) luminaires. Stated simply, the goal of this architecture was to efficiently and cost-effectively convey light from LEDs (point sources) to broad luminaire surfaces (area sources). By simultaneously developing warm-white LED components and low-cost, scalable optical elements, a high system optical efficiency resulted. To meet program goals, Cree evaluated novel approaches to improve LED component efficacy at high color quality while not sacrificing LED optical efficiency relative to conventional packages. Meanwhile, efficiently coupling light from LEDs into modular optical elements, followed by optimally distributing and extracting this light, were challenges that were addressed via novel optical design coupled with frequent experimental evaluations. Minimizing luminaire bill of materials and assembly costs were two guiding principles for all design work, in the effort to achieve luminaires with significantly lower normalized cost ($/klm) than existing LED fixtures. Chief project accomplishments included the achievement of >150 lm/W warm-white LEDs having primary optics compatible with low-cost modular optical elements. In addition, a prototype Light Module optical efficiency of over 90% was measured, demonstrating the potential of this scalable architecture for ultra-high-efficacy LED luminaires. Since the project ended, Cree has continued to evaluate optical element fabrication and assembly methods in an effort to rapidly transfer this scalable, cost-effective technology to Cree production development groups. The Light Module concept is likely to make a strong contribution to the development of new cost-effective, high-efficacy luminaries, thereby accelerating widespread adoption of energy-saving SSL in the U.S.

  2. A low-cost and portable realization on fringe projection three-dimensional measurement

    Science.gov (United States)

    Xiao, Suzhi; Tao, Wei; Zhao, Hui

    2015-12-01

    Fringe projection three-dimensional measurement is widely applied in a wide range of industrial application. The traditional fringe projection system has the disadvantages of high expense, big size, and complicated calibration requirements. In this paper we introduce a low-cost and portable realization on three-dimensional measurement with Pico projector. It has the advantages of low cost, compact physical size, and flexible configuration. For the proposed fringe projection system, there is no restriction to camera and projector's relative alignment on parallelism and perpendicularity for installation. Moreover, plane-based calibration method is adopted in this paper that avoids critical requirements on calibration system such as additional gauge block or precise linear z stage. What is more, error sources existing in the proposed system are introduced in this paper. The experimental results demonstrate the feasibility of the proposed low cost and portable fringe projection system.

  3. Examining the implications of dental treatment costs for low-income families.

    Science.gov (United States)

    Snow, Patrick; McNally, Mary E

    2010-01-01

    Dental disease is concentrated among those with low socioeconomic status. Dental care is not publicly funded, and many Canadians must therefore make difficult financial choices when accessing dental care. Families who live in poverty have difficulty meeting even their most basic household needs, so dental treatment may not be affordable. The objective of this study was to understand how the cost of dental treatment affects the monthly budgets of families with low incomes. A chart review was conducted for a sample of 213 new patients examined at the Dalhousie University dental clinic over a 1-year period. Costs for proposed treatment plans were averaged. The patients" ability to pay for proposed treatment was examined in the context of various income scenarios. Two hundred and one patients were included in the final analysis. Dental treatment costs per patient averaged approximately $1600 for the year, with 42% of the planned treatment completed within the first year. The estimated monthly cost of completed treatment was $55. When the cost of a healthy diet was included in the monthly budget, it was determined that families in Nova Scotia with parents working for minimum wage and those receiving income assistance would experience a 100% shortfall for dental expenses. Low-income families in Nova Scotia were unable to afford both a nutritious diet and dental care. This is disturbing, given the links between a healthy diet and both overall health and dental health. An understanding of the significance of income shortfalls for those with low incomes, especially as they affect even basic nutritional needs, will help dental professionals to appreciate the seriousness of this issue and the difficulties that many Canadians face when trying to access basic dental care.

  4. Predictive Engineering Tools for Injection-Molded Long-Carbon-Thermoplastic Composites: Weight and Cost Analyses

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, Ba Nghiep [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Fifield, Leonard S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Gandhi, Umesh N. [Toyota Research Inst. North America, Ann Arbor, MI (United States); Mori, Steven [MAGNA Exteriors and Interiors Corporation, Aurora, ON (Canada); Wollan, Eric J. [PlastiComp, Inc., Winona, MN (United States)

    2016-08-01

    This project proposed to integrate, optimize and validate the fiber orientation and length distribution models previously developed and implemented in the Autodesk Simulation Moldflow Insight (ASMI) package for injection-molded long-carbon-fiber thermoplastic composites into a cohesive prediction capability. The current effort focused on rendering the developed models more robust and efficient for automotive industry part design to enable weight savings and cost reduction. The project goal has been achieved by optimizing the developed models, improving and integrating their implementations in ASMI, and validating them for a complex 3D LCF thermoplastic automotive part (Figure 1). Both PP and PA66 were used as resin matrices. After validating ASMI predictions for fiber orientation and fiber length for this complex part against the corresponding measured data, in collaborations with Toyota and Magna PNNL developed a method using the predictive engineering tool to assess LCF/PA66 complex part design in terms of stiffness performance. Structural three-point bending analyses of the complex part and similar parts in steel were then performed for this purpose, and the team has then demonstrated the use of stiffness-based complex part design assessment to evaluate weight savings relative to the body system target (≥ 35%) set in Table 2 of DE-FOA-0000648 (AOI #1). In addition, starting from the part-to-part analysis, the PE tools enabled an estimated weight reduction for the vehicle body system using 50 wt% LCF/PA66 parts relative to the current steel system. Also, from this analysis an estimate of the manufacturing cost including the material cost for making the equivalent part in steel has been determined and compared to the costs for making the LCF/PA66 part to determine the cost per “saved” pound.

  5. Passive low-cost inkjet-printed smart skin sensor for structural health monitoring

    KAUST Repository

    Cook, Benjamin Stassen

    2012-11-20

    Monitoring fatigue cracking of large engineering structures is a costly and time-intensive process. The authors\\' present the first low-cost inkjet-printed patch antenna sensor that can passively detect crack formation, orientation and shape by means of resonant frequency shifts in the two resonant modes of the antenna. For the first time, the effect of non-linear crack shapes on the parallel and perpendicular resonant modes of a patch antenna is quantified with simulation and measurement. This study presents a step towards fully integrated, low-cost, conformal and environmentally friendly smart skins for real-time monitoring of large structures. © The Institution of Engineering and Technology 2012.

  6. A Rapid and Low-Cost PCR Thermal Cycler for Infectious Disease Diagnostics.

    Directory of Open Access Journals (Sweden)

    Kamfai Chan

    Full Text Available The ability to make rapid diagnosis of infectious diseases broadly available in a portable, low-cost format would mark a great step forward in global health. Many molecular diagnostic assays are developed based on using thermal cyclers to carry out polymerase chain reaction (PCR and reverse-transcription PCR for DNA and RNA amplification and detection, respectively. Unfortunately, most commercial thermal cyclers are expensive and need continuous electrical power supply, so they are not suitable for uses in low-resource settings. We have previously reported a low-cost and simple approach to amplify DNA using vacuum insulated stainless steel thermoses food cans, which we have named it thermos thermal cycler or TTC. Here, we describe the use of an improved set up to enable the detection of viral RNA targets by reverse-transcription PCR (RT-PCR, thus expanding the TTC's ability to identify highly infectious, RNA virus-based diseases in low resource settings. The TTC was successful in demonstrating high-speed and sensitive detection of DNA or RNA targets of sexually transmitted diseases, HIV/AIDS, Ebola hemorrhagic fever, and dengue fever. Our innovative TTC costs less than $200 to build and has a capacity of at least eight tubes. In terms of speed, the TTC's performance exceeded that of commercial thermal cyclers tested. When coupled with low-cost endpoint detection technologies such as nucleic acid lateral-flow assay or a cell-phone-based fluorescence detector, the TTC will increase the availability of on-site molecular diagnostics in low-resource settings.

  7. Low-cost photonic sensors for carbon dioxide exchange rate measurement

    Science.gov (United States)

    Bieda, Marcin S.; Sobotka, Piotr; Lesiak, Piotr; Woliński, Tomasz R.

    2017-10-01

    Carbon dioxide (CO2) measurement has an important role in atmosphere monitoring. Usually, two types of measurements are carried out. The first one is based on gas concentration measurement while the second involves gas exchange rate measurement between earth surface and atmosphere [1]. There are several methods which allow gas concentration measurement. However, most of them require expensive instrumentation or large devices (i.e. gas chambers). In order to precisely measure either CO2 concentration or CO2 exchange rate, preferably a sensors network should be used. These sensors must have small dimensions, low power consumption, and they should be cost-effective. Therefore, this creates a great demand for a robust low-power and low-cost CO2 sensor [2,3]. As a solution, we propose a photonic sensor that can measure CO2 concentration and also can be used to measure gas exchange by using the Eddy covariance method [1].

  8. DEVELOPMENT OF A LOW COST CAMERA FOR AGING ACCELERATED POLYMERS

    Directory of Open Access Journals (Sweden)

    Carlos Henrique Duarte Felisbino

    2018-03-01

    Full Text Available The objective of this paper is to describe the design, construction and testing of a low cost chamber for accelerated aging of polymers that meets a low and high ultraviolet radiation cycle on the test specimens in accordance with ASTM G154. The methodology was based on the survey of the standards related to the tests of accelerated aging of polymers and of the existing equipment, providing the subsidies for the development of the project, which was validated by the construction and evaluation of its performance. The camera control is performed by an Arduino-based electronic system and uses commercially available components that meet project specifications. The equipment met the requirements for both the specifications and the low cost and will integrate the laboratories of the University of Mogi das Cruzes (UMC, Villa-Lobos campus, to carry out tests on polymer materials.

  9. Low cost construction technologies and materials - case study Mozambuique

    CSIR Research Space (South Africa)

    Kuchena, JC

    2009-09-01

    Full Text Available Low cost or affordable construction technologies and materials are often touted as a panacea in meeting the ever growing demand for rapid housing delivery in developing economies. Mozambique as with most of the developing world, from both historical...

  10. NetPICOmag: A low-cost networked magnetometer and its applications

    Science.gov (United States)

    Schofield, I.; Connors, M.; Russell, C. T.

    2012-03-01

    NetPICOmag (NPM) is the culmination of a design effort to build a compact, low-cost, laboratory-grade, networked magnetometer designed for remote autonomous operation, suited for research and education. NPM allows wide placement of magnetometers sensitive enough to detect auroral activity and the daily variation, and is suitable for education projects and a range of geophysical applications. The use of networked microcontrollers and GPS timing is applicable to other small instruments for field or local deployment, and an onboard data logging capability has also been demonstrated. We illustrate the value of the placement of low-cost magnetometers to increase coverage in an area through the study of a Pc 5 pulsation event which took place on September 4, 2010. By combining results with those from auroral zone magnetometers supporting the THEMIS project, we find that the phase velocity of these morning sector pulsations was northward on the ground. The event took place under very quiet solar wind conditions, and credible mapping associates it with the inner magnetosphere. Another aspect beyond increasing areal coverage is increasing density of coverage, which becomes feasible with instruments of very low cost. We examine aspects of the April 5, 2010 space weather event which are possible to deduce from closely spaced magnetometers.

  11. Low-Cost Superconducting Wire for Wind Generators: High Performance, Low Cost Superconducting Wires and Coils for High Power Wind Generators

    Energy Technology Data Exchange (ETDEWEB)

    None

    2012-01-01

    REACT Project: The University of Houston will develop a low-cost, high-current superconducting wire that could be used in high-power wind generators. Superconducting wire currently transports 600 times more electric current than a similarly sized copper wire, but is significantly more expensive. The University of Houston’s innovation is based on engineering nanoscale defects in the superconducting film. This could quadruple the current relative to today’s superconducting wires, supporting the same amount of current using 25% of the material. This would make wind generators lighter, more powerful and more efficient. The design could result in a several-fold reduction in wire costs and enable their commercial viability of high-power wind generators for use in offshore applications.

  12. A low-cost vaporization-atomization system for atomic absorption spectrometry

    International Nuclear Information System (INIS)

    Bruhn F, C.G.; Ambiado V, F.; Woerner V, R.

    1990-01-01

    A low-cost vaporization-atomization system for atomic absorption spectrometry is developed as an alternative to the use of a graphite furnace in electrothermal atomic absorption spectrometry. (Author)

  13. Rapid, low-cost, image analysis through video processing

    International Nuclear Information System (INIS)

    Levinson, R.A.; Marrs, R.W.; Grantham, D.G.

    1976-01-01

    Remote Sensing now provides the data necessary to solve many resource problems. However, many of the complex image processing and analysis functions used in analysis of remotely-sensed data are accomplished using sophisticated image analysis equipment. High cost of this equipment places many of these techniques beyond the means of most users. A new, more economical, video system capable of performing complex image analysis has now been developed. This report describes the functions, components, and operation of that system. Processing capability of the new video image analysis system includes many of the tasks previously accomplished with optical projectors and digital computers. Video capabilities include: color separation, color addition/subtraction, contrast stretch, dark level adjustment, density analysis, edge enhancement, scale matching, image mixing (addition and subtraction), image ratioing, and construction of false-color composite images. Rapid input of non-digital image data, instantaneous processing and display, relatively low initial cost, and low operating cost gives the video system a competitive advantage over digital equipment. Complex pre-processing, pattern recognition, and statistical analyses must still be handled through digital computer systems. The video system at the University of Wyoming has undergone extensive testing, comparison to other systems, and has been used successfully in practical applications ranging from analysis of x-rays and thin sections to production of color composite ratios of multispectral imagery. Potential applications are discussed including uranium exploration, petroleum exploration, tectonic studies, geologic mapping, hydrology sedimentology and petrography, anthropology, and studies on vegetation and wildlife habitat

  14. Low-cost electrodes for stable perovskite solar cells

    Science.gov (United States)

    Bastos, João P.; Manghooli, Sara; Jaysankar, Manoj; Tait, Jeffrey G.; Qiu, Weiming; Gehlhaar, Robert; De Volder, Michael; Uytterhoeven, Griet; Poortmans, Jef; Paetzold, Ulrich W.

    2017-06-01

    Cost-effective production of perovskite solar cells on an industrial scale requires the utilization of exclusively inexpensive materials. However, to date, highly efficient and stable perovskite solar cells rely on expensive gold electrodes since other metal electrodes are known to cause degradation of the devices. Finding a low-cost electrode that can replace gold and ensure both efficiency and long-term stability is essential for the success of the perovskite-based solar cell technology. In this work, we systematically compare three types of electrode materials: multi-walled carbon nanotubes (MWCNTs), alternative metals (silver, aluminum, and copper), and transparent oxides [indium tin oxide (ITO)] in terms of efficiency, stability, and cost. We show that multi-walled carbon nanotubes are the only electrode that is both more cost-effective and stable than gold. Devices with multi-walled carbon nanotube electrodes present remarkable shelf-life stability, with no decrease in the efficiency even after 180 h of storage in 77% relative humidity (RH). Furthermore, we demonstrate the potential of devices with multi-walled carbon nanotube electrodes to achieve high efficiencies. These developments are an important step forward to mass produce perovskite photovoltaics in a commercially viable way.

  15. Cost-benefit study of consumer product take-back programs using IBM's WIT reverse logistics optimization tool

    Science.gov (United States)

    Veerakamolmal, Pitipong; Lee, Yung-Joon; Fasano, J. P.; Hale, Rhea; Jacques, Mary

    2002-02-01

    In recent years, there has been increased focus by regulators, manufacturers, and consumers on the issue of product end of life management for electronics. This paper presents an overview of a conceptual study designed to examine the costs and benefits of several different Product Take Back (PTB) scenarios for used electronics equipment. The study utilized a reverse logistics supply chain model to examine the effects of several different factors in PTB programs. The model was done using the IBM supply chain optimization tool known as WIT (Watson Implosion Technology). Using the WIT tool, we were able to determine a theoretical optimal cost scenario for PTB programs. The study was designed to assist IBM internally in determining theoretical optimal Product Take Back program models and determining potential incentives for increasing participation rates.

  16. Magnet costs for the Advanced Light Source

    International Nuclear Information System (INIS)

    Tanabe, J.; Krupnick, J.; Hoyer, E.; Paterson, A.

    1993-05-01

    The Advanced Light Source (ALS) accelerator is now completed. The numerous conventional magnets required for the booster ring, the storage ring and the low and high energy transfer lines were installed during the last two years. This paper summarizes the various costs associated with the quantity fabrication of selected magnet families. These costs include the costs of prototypes, tooling, coil and core fabrication, assembly and magnetic measurements. Brief descriptions of the magnets and specialized requirements for magnetic measurements are included in order to associate the costs with the relative complexities of the various magnet systems

  17. Feasibility and economic evaluation of low-cost evaporative cooling ...

    African Journals Online (AJOL)

    Feasibility and economic evaluation of low-cost evaporative cooling system in fruit and vegetables storage. ... on fruit and vegetables quality during harvesting, transportation, storage and marketing. ... The coolers were found to be effective in maintaining micro-environmental conditions for ... AJOL African Journals Online.

  18. A low-cost potentiostat for point-of-need diagnostics

    CSIR Research Space (South Africa)

    Bezuidenhout, Petrone H

    2017-09-01

    Full Text Available The work presented details the development of a lowcost potentiostat, with the aim of creating an ink-jet printed hybrid paper-based low-cost sensing system for rapid water quality monitoring. Potentiostats exhibit high sensitivities and can be used...

  19. A Low Cost, Hybrid Approach to Data Mining, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The proposed effort will combine a low cost physical modeling approach with inductive, data-centered modeling in an aerosopace relevant context to demonstrate...

  20. Low-Weight, Durable, and Low-Cost Metal Rubber Sensor System for Ultra Long Duration Scientific Balloons, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — NanoSonic proposes to develop an innovative, low-cost, ultra low mass density, and non-intrusive sensor system for ultra long duration balloons (ULDB) that will...

  1. Low-cost silicon wafer dicing using a craft cutter

    KAUST Repository

    Fan, Yiqiang

    2014-05-20

    This paper reports a low-cost silicon wafer dicing technique using a commercial craft cutter. The 4-inch silicon wafers were scribed using a crafter cutter with a mounted diamond blade. The pre-programmed automated process can reach a minimum die feature of 3 mm by 3 mm. We performed this scribing process on the top polished surface of a silicon wafer; we also created a scribing method for the back-unpolished surface in order to protect the structures on the wafer during scribing. Compared with other wafer dicing methods, our proposed dicing technique is extremely low cost (lower than $1,000), and suitable for silicon wafer dicing in microelectromechanical or microfluidic fields, which usually have a relatively large die dimension. The proposed dicing technique is also usable for dicing multiple project wafers, a process where dies of different dimensions are diced on the same wafer.

  2. Consequent use of IT tools as a driver for cost reduction and quality improvements

    Science.gov (United States)

    Hein, Stefan; Rapp, Roberto; Feustel, Andreas

    2013-10-01

    The semiconductor industry drives a lot of efforts in the field of cost reductions and quality improvements. The consequent use of IT tools is one possibility to support these goals. With the extensions of its 150mm Fab to 200mm Robert Bosch increased the systematic use of data analysis and Advanced Process Control (APC).

  3. Cost of Mastitis in Scottish Dairy Herds with Low and High Subclinical Mastitis Problems

    OpenAIRE

    YALÇIN, Cengiz

    2000-01-01

    The aim of this study was to estimate the cost of mastitis and the contribution of each cost component of mastitis to the total mastitis induced cost in herds with low and high levels of subclinical mastitis under Scottish field conditions. It was estimated that mastitis cost £140 per cow/year to the average Scottish dairy farmer in 1996. However, this figure was as low as £69 per cow/year in herds with lower levels of subclinical mastitis, and as high as £228 cow/year in herds with high s...

  4. effect of turning parameters on metal removal and tool wear rates

    African Journals Online (AJOL)

    user

    2 SCHOOL OF AEROSPACE, TRANSPORT AND MANUFACTURING, CRANFIELD UNIV., ... AISI 1018 low carbon steel during turning operation to reduce tooling costs as a result of tool wear and achieve optimum metal ... performance of a system, part or component while ... traditional and experimental design methods of.

  5. Low-cost fabrication technologies for nanostructures: state-of-the-art and potential

    International Nuclear Information System (INIS)

    Santos, A; Deen, M J; Marsal, L F

    2015-01-01

    In the last decade, some low-cost nanofabrication technologies used in several disciplines of nanotechnology have demonstrated promising results in terms of versatility and scalability for producing innovative nanostructures. While conventional nanofabrication technologies such as photolithography are and will be an important part of nanofabrication, some low-cost nanofabrication technologies have demonstrated outstanding capabilities for large-scale production, providing high throughputs with acceptable resolution and broad versatility. Some of these nanotechnological approaches are reviewed in this article, providing information about the fundamentals, limitations and potential future developments towards nanofabrication processes capable of producing a broad range of nanostructures. Furthermore, in many cases, these low-cost nanofabrication approaches can be combined with traditional nanofabrication technologies. This combination is considered a promising way of generating innovative nanostructures suitable for a broad range of applications such as in opto-electronics, nano-electronics, photonics, sensing, biotechnology or medicine. (topical review)

  6. Suppression of Noise to Obtain a High-Performance Low-Cost Optical Encoder

    Directory of Open Access Journals (Sweden)

    Sergio Alvarez-Rodríguez

    2018-01-01

    Full Text Available Currently, commercial encoders endowed with high precision are expensive sensors, and optical low-cost designs to measure the positioning angle have undesirable levels of system noise which reduce the good performance of devices. This research is devoted to the designing of mathematical filters to suppress noise in polarized transducers, in order to obtain high accuracy, precision, and resolution, along with an adaptive maximum response speed for low-cost optical encoders. This design was proved through a prototype inside a research platform, and experimental results show an accuracy of 3.9, a precision of 26, and a resolution of 17 [arc seconds], at least for the specified working conditions, for the sensing of the angular position of a rotary polarizer. From this work has been obtained a high-performance low-cost polyphase optical encoder, which uses filtering mathematical principles potentially generalizable to other inventions.

  7. Low-cost fabrication technologies for nanostructures: state-of-the-art and potential

    Science.gov (United States)

    Santos, A.; Deen, M. J.; Marsal, L. F.

    2015-01-01

    In the last decade, some low-cost nanofabrication technologies used in several disciplines of nanotechnology have demonstrated promising results in terms of versatility and scalability for producing innovative nanostructures. While conventional nanofabrication technologies such as photolithography are and will be an important part of nanofabrication, some low-cost nanofabrication technologies have demonstrated outstanding capabilities for large-scale production, providing high throughputs with acceptable resolution and broad versatility. Some of these nanotechnological approaches are reviewed in this article, providing information about the fundamentals, limitations and potential future developments towards nanofabrication processes capable of producing a broad range of nanostructures. Furthermore, in many cases, these low-cost nanofabrication approaches can be combined with traditional nanofabrication technologies. This combination is considered a promising way of generating innovative nanostructures suitable for a broad range of applications such as in opto-electronics, nano-electronics, photonics, sensing, biotechnology or medicine.

  8. Low-input, low-cost IPM program helps manage potato psyllid

    Directory of Open Access Journals (Sweden)

    Sean M. Prager

    2016-04-01

    Full Text Available Potato psyllid is a pest of solanaceous plants throughout much of the western United States, including California, where it has increased and is now overwintering. The psyllid affects its plant hosts from direct feeding and by transmitting a plant pathogenic bacterium, Lso. Millions of dollars of damages have occurred in the U.S. potato industry, and a large acreage of crops is susceptible in California. Control is complicated because different crops have different pest complexes and susceptibilities to Lso; currently most growers use multiple pesticide applications, including broad-spectrum insecticides. Results of our field trials at South Coast Research and Extension Center indicate that the use of broad-spectrum insecticides actually increases psyllid numbers in both peppers and potatoes. We have developed a low-input IPM program, which in field trials produced encouraging results in peppers, potatoes and tomatoes compared to broad-spectrum insecticides. Economic analysis showed the low-input IPM approach was more cost effective than a standard insecticide program in tomatoes.

  9. Comparative investigations of manual action representations: evidence that chimpanzees represent the costs of potential future actions involving tools.

    Science.gov (United States)

    Frey, Scott H; Povinelli, Daniel J

    2012-01-12

    The ability to adjust one's ongoing actions in the anticipation of forthcoming task demands is considered as strong evidence for the existence of internal action representations. Studies of action selection in tool use reveal that the behaviours that we choose in the present moment differ depending on what we intend to do next. Further, they point to a specialized role for mechanisms within the human cerebellum and dominant left cerebral hemisphere in representing the likely sensory costs of intended future actions. Recently, the question of whether similar mechanisms exist in other primates has received growing, but still limited, attention. Here, we present data that bear on this issue from a species that is a natural user of tools, our nearest living relative, the chimpanzee. In experiment 1, a subset of chimpanzees showed a non-significant tendency for their grip preferences to be affected by anticipation of the demands associated with bringing a tool's baited end to their mouths. In experiment 2, chimpanzees' initial grip preferences were consistently affected by anticipation of the forthcoming movements in a task that involves using a tool to extract a food reward. The partial discrepancy between the results of these two studies is attributed to the ability to accurately represent differences between the motor costs associated with executing the two response alternatives available within each task. These findings suggest that chimpanzees are capable of accurately representing the costs of intended future actions, and using those predictions to select movements in the present even in the context of externally directed tool use.

  10. Low-cost, solution processable carbon nanotube supercapacitors and their characterization

    Science.gov (United States)

    Lehtimäki, Suvi; Tuukkanen, Sampo; Pörhönen, Juho; Moilanen, Pasi; Virtanen, Jorma; Honkanen, Mari; Lupo, Donald

    2014-06-01

    We report ecological and low-cost carbon nanotube (CNT) supercapacitors fabricated using a simple, scalable solution processing method, where the use of a highly porous and electrically conductive active material eliminates the need for a current collector. Electrodes were fabricated on a poly(ethylene terephthalate) substrate from a printable multi-wall CNT ink, where the CNTs are solubilized in water using xylan as a dispersion agent. The dispersion method facilitates a very high concentration of CNTs in the ink. Supercapacitors were assembled using a paper separator and an aqueous NaCl electrolyte and the devices were characterized with a galvanostatic discharge method defined by an industrial standard. The capacitance of the 2 cm^2 devices was 6 mF/cm^2 (2.3 F/g) and equivalent series resistance 80 Ω . Low-cost supercapacitors fabricated from safe and environmentally friendly materials have potential applications as energy storage devices in ubiquitous and autonomous intelligence as well as in disposable low-end products.

  11. Metal-free supercapacitor with aqueous electrolyte and low-cost carbon materials

    Science.gov (United States)

    Blomquist, Nicklas; Wells, Thomas; Andres, Britta; Bäckström, Joakim; Forsberg, Sven; Olin, Håkan

    2017-01-01

    Electric double-layer capacitors (EDLCs) or supercapacitors (SCs) are fast energy storage devices with high pulse efficiency and superior cyclability, which makes them useful in various applications including electronics, vehicles and grids. Aqueous SCs are considered to be more environmentally friendly than those based on organic electrolytes. Because of the corrosive nature of the aqueous environment, however, expensive electrochemically stable materials are needed for the current collectors and electrodes in aqueous SCs. This results in high costs for a given energy-storage capacity. To address this, we developed a novel low-cost aqueous SC using graphite foil as the current collector and a mix of graphene, nanographite, simple water-purification carbons and nanocellulose as electrodes. The electrodes were coated directly onto the graphite foil by using casting frames and the SCs were assembled in a pouch cell design. With this approach, we achieved a material cost reduction of greater than 90% while maintaining approximately one-half of the specific capacitance of a commercial unit, thus demonstrating that the proposed SC can be an environmentally friendly, low-cost alternative to conventional SCs.

  12. Application of automation for low cost aircraft cabin simulator

    NARCIS (Netherlands)

    Tan, C.F.; Chen, W.; Boomen, van den G.J.A.; Rauterberg, G.W.M.

    2010-01-01

    This paper presents an application of automation for low cost aircraft cabin simulator. The aircraft cabin simulator is a testbed that was designed for research on aircraft passenger comfort mprovement product. The simulator consists of an economy class section, a business class section, a lavatory

  13. Development of an improved low profile hub seal refurbishment tool

    International Nuclear Information System (INIS)

    Wagg, L.

    1997-01-01

    The hub seal area of a fuel channel feeder coupling can be exposed to oxygen in the atmosphere if protective measures are not taken during maintenance outages. Exposure to oxygen can lead to pitting of the hub seal area. Although this is a rare occurrence, the resulting possibility of the feeder coupling leakage led to the development of a feeder hub refurbishment tool. To reduce time and man-rem exposure during feeder hub seal refurbishment, an improved low profile hub seat refurbishing tool has been developed. The improved tool design will allow for quick and controlled removal of material, and the restoration of a roll-burnished finish equivalent to the original requirements. The new tool can be used in maintenance operations, with the end fitting present, as well as under retube-type circumstances, with the end fitting removed. (author)

  14. Performance Evaluation of Low Cost LoRa Modules in IoT Applications

    Science.gov (United States)

    Daud, Shuhaizar; Shi Yang, Teoh; Asmi Romli, Muhamad; Awang Ahmad, Zahari; Mahrom, Norfadila; Raof, Rafikha Aliana A.

    2018-03-01

    LoRa is a low power long range wireless communication platform that is designed as an efficient communication platform for small, low powered devices. This makes it very suitable for battery powered devices and IoT implementation. This paper evaluates some low cost LoRa modules available on the market and their suitability, energy efficiency and performance during operation. Two low cost LoRa transceiver from Semtech Industries, the SX1272 and SX1278 were tested for their power consumption and maximum transmission range. This study have evaluated the two LoRa solutions and found that the SX1278 have a better transmission range and uses lower energy compared to the SX1272 thus making it more suitable for embedded implementation as a data gateway.

  15. Performance Analysis of Low-Cost Single-Frequency GPS Receivers in Hydrographic Surveying

    Science.gov (United States)

    Elsobeiey, M.

    2017-10-01

    The International Hydrographic Organization (IHO) has issued standards that provide the minimum requirements for different types of hydrographic surveys execution to collect data to be used to compile navigational charts. Such standards are usually updated from time to time to reflect new survey techniques and practices and must be achieved to assure both surface navigation safety and marine environment protection. Hydrographic surveys can be classified to four orders namely, special order, order 1a, order 1b, and order 2. The order of hydrographic surveys to use should be determined in accordance with the importance to the safety of navigation in the surveyed area. Typically, geodetic-grade dual-frequency GPS receivers are utilized for position determination during data collection in hydrographic surveys. However, with the evolution of high-sensitivity low-cost single-frequency receivers, it is very important to evaluate the performance of such receivers. This paper investigates the performance of low-cost single-frequency GPS receivers in hydrographic surveying applications. The main objective is to examine whether low-cost single-frequency receivers fulfil the IHO standards for hydrographic surveys. It is shown that the low-cost single-frequency receivers meet the IHO horizontal accuracy for all hydrographic surveys orders at any depth. However, the single-frequency receivers meet only order 2 requirements for vertical accuracy at depth more than or equal 100 m.

  16. Low-cost multispectral imaging for remote sensing of lettuce health

    Science.gov (United States)

    Ren, David D. W.; Tripathi, Siddhant; Li, Larry K. B.

    2017-01-01

    In agricultural remote sensing, unmanned aerial vehicle (UAV) platforms offer many advantages over conventional satellite and full-scale airborne platforms. One of the most important advantages is their ability to capture high spatial resolution images (1-10 cm) on-demand and at different viewing angles. However, UAV platforms typically rely on the use of multiple cameras, which can be costly and difficult to operate. We present the development of a simple low-cost imaging system for remote sensing of crop health and demonstrate it on lettuce (Lactuca sativa) grown in Hong Kong. To identify the optimal vegetation index, we recorded images of both healthy and unhealthy lettuce, and used them as input in an expectation maximization cluster analysis with a Gaussian mixture model. Results from unsupervised and supervised clustering show that, among four widely used vegetation indices, the blue wide-dynamic range vegetation index is the most accurate. This study shows that it is readily possible to design and build a remote sensing system capable of determining the health status of lettuce at a reasonably low cost (lettuce growers.

  17. Cost effectiveness of medical devices to diagnose pre-eclampsia in low-resource settings

    Directory of Open Access Journals (Sweden)

    Zoë M. McLaren

    Full Text Available Background: Maternal mortality remains a major health challenge facing developing countries, with pre-eclampsia accounting for up to 17% of maternal deaths. Diagnosis requires skilled health providers and devices that are appropriate for low-resource settings. This study presents the first cost-effectiveness analysis of multiple medical devices used to diagnose pre-eclampsia in low- and middle-income countries (LMICs. Methods: Blood pressure and proteinuria measurement devices, identified from compendia for LMICs, were included. We developed a decision tree framework to assess the cost-effectiveness of each device using parameter values that reflect the general standard of care based on a survey of relevant literature and expert opinion. We examined the sensitivity of our results using one-way and second-order probabilistic multivariate analyses. Results: Because the disability-adjusted life years (DALYs averted for each device were very similar, the results were influenced by the per-use cost ranking. The most cost-effective device combination was a semi-automatic blood pressure measurement device and visually read urine strip test with the lowest combined per-use cost of $0.2004 and an incremental cost effectiveness ratio of $93.6 per DALY gained relative to a baseline with no access to diagnostic devices. When access to treatment is limited, it is more cost-effective to improve access to treatment than to increase testing rates or diagnostic device sensitivity. Conclusions: Our findings were not sensitive to changes in device sensitivity, however they were sensitive to changes in the testing rate and treatment rate. Furthermore, our results suggest that simple devices are more cost-effective than complex devices. The results underscore the desirability of two design features for LMICs: ease of use and accuracy without calibration. Our findings have important implications for policy makers, health economists, health care providers and

  18. Utilizing time-driven activity-based costing to understand the short- and long-term costs of treating localized, low-risk prostate cancer.

    Science.gov (United States)

    Laviana, Aaron A; Ilg, Annette M; Veruttipong, Darlene; Tan, Hung-Jui; Burke, Michael A; Niedzwiecki, Douglas R; Kupelian, Patrick A; King, Chris R; Steinberg, Michael L; Kundavaram, Chandan R; Kamrava, Mitchell; Kaplan, Alan L; Moriarity, Andrew K; Hsu, William; Margolis, Daniel J A; Hu, Jim C; Saigal, Christopher S

    2016-02-01

    Given the costs of delivering care for men with prostate cancer remain poorly described, this article reports the results of time-driven activity-based costing (TDABC) for competing treatments of low-risk prostate cancer. Process maps were developed for each phase of care from the initial urologic visit through 12 years of follow-up for robotic-assisted laparoscopic prostatectomy (RALP), cryotherapy, high-dose rate (HDR) and low-dose rate (LDR) brachytherapy, intensity-modulated radiation therapy (IMRT), stereotactic body radiation therapy (SBRT), and active surveillance (AS). The last modality incorporated both traditional transrectal ultrasound (TRUS) biopsy and multiparametric-MRI/TRUS fusion biopsy. The costs of materials, equipment, personnel, and space were calculated per unit of time and based on the relative proportion of capacity used. TDABC for each treatment was defined as the sum of its resources. Substantial cost variation was observed at 5 years, with costs ranging from $7,298 for AS to $23,565 for IMRT, and they remained consistent through 12 years of follow-up. LDR brachytherapy ($8,978) was notably cheaper than HDR brachytherapy ($11,448), and SBRT ($11,665) was notably cheaper than IMRT, with the cost savings attributable to shorter procedure times and fewer visits required for treatment. Both equipment costs and an inpatient stay ($2,306) contributed to the high cost of RALP ($16,946). Cryotherapy ($11,215) was more costly than LDR brachytherapy, largely because of increased single-use equipment costs ($6,292 vs $1,921). AS reached cost equivalence with LDR brachytherapy after 7 years of follow-up. The use of TDABC is feasible for analyzing cancer services and provides insights into cost-reduction tactics in an era focused on emphasizing value. By detailing all steps from diagnosis and treatment through 12 years of follow-up for low-risk prostate cancer, this study has demonstrated significant cost variation between competing treatments. © 2015

  19. Partial Discharge Monitoring in Power Transformers Using Low-Cost Piezoelectric Sensors.

    Science.gov (United States)

    Castro, Bruno; Clerice, Guilherme; Ramos, Caio; Andreoli, André; Baptista, Fabricio; Campos, Fernando; Ulson, José

    2016-08-10

    Power transformers are crucial in an electric power system. Failures in transformers can affect the quality and cause interruptions in the power supply. Partial discharges are a phenomenon that can cause failures in the transformers if not properly monitored. Typically, the monitoring requires high-cost corrective maintenance or even interruptions of the power system. Therefore, the development of online non-invasive monitoring systems to detect partial discharges in power transformers has great relevance since it can reduce significant maintenance costs. Although commercial acoustic emission sensors have been used to monitor partial discharges in power transformers, they still represent a significant cost. In order to overcome this drawback, this paper presents a study of the feasibility of low-cost piezoelectric sensors to identify partial discharges in mineral insulating oil of power transformers. The analysis of the feasibility of the proposed low-cost sensor is performed by its comparison with a commercial acoustic emission sensor commonly used to detect partial discharges. The comparison between the responses in the time and frequency domain of both sensors was carried out and the experimental results indicate that the proposed piezoelectric sensors have great potential in the detection of acoustic waves generated by partial discharges in insulation oil, contributing for the popularization of this noninvasive technique.

  20. Partial Discharge Monitoring in Power Transformers Using Low-Cost Piezoelectric Sensors

    Directory of Open Access Journals (Sweden)

    Bruno Castro

    2016-08-01

    Full Text Available Power transformers are crucial in an electric power system. Failures in transformers can affect the quality and cause interruptions in the power supply. Partial discharges are a phenomenon that can cause failures in the transformers if not properly monitored. Typically, the monitoring requires high-cost corrective maintenance or even interruptions of the power system. Therefore, the development of online non-invasive monitoring systems to detect partial discharges in power transformers has great relevance since it can reduce significant maintenance costs. Although commercial acoustic emission sensors have been used to monitor partial discharges in power transformers, they still represent a significant cost. In order to overcome this drawback, this paper presents a study of the feasibility of low-cost piezoelectric sensors to identify partial discharges in mineral insulating oil of power transformers. The analysis of the feasibility of the proposed low-cost sensor is performed by its comparison with a commercial acoustic emission sensor commonly used to detect partial discharges. The comparison between the responses in the time and frequency domain of both sensors was carried out and the experimental results indicate that the proposed piezoelectric sensors have great potential in the detection of acoustic waves generated by partial discharges in insulation oil, contributing for the popularization of this noninvasive technique.

  1. Cost Benefit Analysis: Cost Benefit Analysis for Human Effectiveness Research: Bioacoustic Protection

    Science.gov (United States)

    2001-07-21

    APPENDIX A. ACRONYMS ACCES Attenuating Custom Communication Earpiece System ACEIT Automated Cost estimating Integrated Tools AFSC Air Force...documented in the ACEIT cost estimating tool developed by Tecolote, Inc. The factor used was 14 percent of PMP. 1.3 System Engineering/ Program...The data source is the ASC Aeronautical Engineering Products Cost Factor Handbook which is documented in the ACEIT cost estimating tool developed

  2. Standard semiconductor packaging for high-reliability low-cost MEMS applications

    Science.gov (United States)

    Harney, Kieran P.

    2005-01-01

    Microelectronic packaging technology has evolved over the years in response to the needs of IC technology. The fundamental purpose of the package is to provide protection for the silicon chip and to provide electrical connection to the circuit board. Major change has been witnessed in packaging and today wafer level packaging technology has further revolutionized the industry. MEMS (Micro Electro Mechanical Systems) technology has created new challenges for packaging that do not exist in standard ICs. However, the fundamental objective of MEMS packaging is the same as traditional ICs, the low cost and reliable presentation of the MEMS chip to the next level interconnect. Inertial MEMS is one of the best examples of the successful commercialization of MEMS technology. The adoption of MEMS accelerometers for automotive airbag applications has created a high volume market that demands the highest reliability at low cost. The suppliers to these markets have responded by exploiting standard semiconductor packaging infrastructures. However, there are special packaging needs for MEMS that cannot be ignored. New applications for inertial MEMS devices are emerging in the consumer space that adds the imperative of small size to the need for reliability and low cost. These trends are not unique to MEMS accelerometers. For any MEMS technology to be successful the packaging must provide the basic reliability and interconnection functions, adding the least possible cost to the product. This paper will discuss the evolution of MEMS packaging in the accelerometer industry and identify the main issues that needed to be addressed to enable the successful commercialization of the technology in the automotive and consumer markets.

  3. sequential low cost interventions double hand hygiene rates among

    African Journals Online (AJOL)

    2014-02-02

    Feb 2, 2014 ... Request for reprints to: Onyema Ogbuagu, Yale University School of Medicine, Address – 135 College Street, suite 323, ... Objective: To assess the impact of multimodal low-cost interventions on hand hygiene ... system change including investment in provision ... Statistical software used was IBM SPSS.

  4. System Considerations and Challendes in 3d Mapping and Modeling Using Low-Cost Uav Systems

    Science.gov (United States)

    Lari, Z.; El-Sheimy, N.

    2015-08-01

    In the last few years, low-cost UAV systems have been acknowledged as an affordable technology for geospatial data acquisition that can meet the needs of a variety of traditional and non-traditional mapping applications. In spite of its proven potential, UAV-based mapping is still lacking in terms of what is needed for it to become an acceptable mapping tool. In other words, a well-designed system architecture that considers payload restrictions as well as the specifications of the utilized direct geo-referencing component and the imaging systems in light of the required mapping accuracy and intended application is still required. Moreover, efficient data processing workflows, which are capable of delivering the mapping products with the specified quality while considering the synergistic characteristics of the sensors onboard, the wide range of potential users who might lack deep knowledge in mapping activities, and time constraints of emerging applications, are still needed to be adopted. Therefore, the introduced challenges by having low-cost imaging and georeferencing sensors onboard UAVs with limited payload capability, the necessity of efficient data processing techniques for delivering required products for intended applications, and the diversity of potential users with insufficient mapping-related expertise needs to be fully investigated and addressed by UAV-based mapping research efforts. This paper addresses these challenges and reviews system considerations, adaptive processing techniques, and quality assurance/quality control procedures for achievement of accurate mapping products from these systems.

  5. Low-cost microcontroller platform for studying lymphatic biomechanics in vitro.

    Science.gov (United States)

    Kornuta, Jeffrey A; Nipper, Matthew E; Dixon, J Brandon

    2013-01-04

    The pumping innate to collecting lymphatic vessels routinely exposes the endothelium to oscillatory wall shear stress and other dynamic forces. However, studying the mechanical sensitivity of the lymphatic endothelium remains a difficult task due to limitations of commercial or custom systems to apply a variety of time-varying stresses in vitro. Current biomechanical in vitro testing devices are very expensive, limited in capability, or highly complex; rendering them largely inaccessible to the endothelial cell biology community. To address these shortcomings, the authors propose a reliable, low-cost platform for augmenting the capabilities of commercially available pumps to produce a wide variety of flow rate waveforms. In particular, the Arduino Uno, a microcontroller development board, is used to provide open-loop control of a digital peristaltic pump using precisely timed serial commands. In addition, the flexibility of this platform is further demonstrated through its support of a custom-built cell-straining device capable of producing oscillatory strains with varying amplitudes and frequencies. Hence, this microcontroller development board is shown to be an inexpensive, precise, and easy-to-use tool for supplementing in vitro assays to quantify the effects of biomechanical forces on lymphatic endothelial cells. Copyright © 2012 Elsevier Ltd. All rights reserved.

  6. Waste Management Facilities cost information for mixed low-level waste. Revision 1

    International Nuclear Information System (INIS)

    Shropshire, D.; Sherick, M.; Biadgi, C.

    1995-06-01

    This report contains preconceptual designs and planning level life-cycle cost estimates for managing mixed low-level waste. The report's information on treatment, storage, and disposal modules can be integrated to develop total life-cycle costs for various waste management options. A procedure to guide the US Department of Energy and its contractor personnel in the use of cost estimation data is also summarized in this report

  7. Reliable, Low-Cost, Low-Weight, Non-Hermetic Coating for MCM Applications

    Science.gov (United States)

    Jones, Eric W.; Licari, James J.

    2000-01-01

    Through an Air Force Research Laboratory sponsored STM program, reliable, low-cost, low-weight, non-hermetic coatings for multi-chip-module(MCK applications were developed. Using the combination of Sandia Laboratory ATC-01 test chips, AvanTeco's moisture sensor chips(MSC's), and silicon slices, we have shown that organic and organic/inorganic overcoatings are reliable and practical non-hermetic moisture and oxidation barriers. The use of the MSC and unpassivated ATC-01 test chips provided rapid test results and comparison of moisture barrier quality of the overcoatings. The organic coatings studied were Parylene and Cyclotene. The inorganic coatings were Al2O3 and SiO2. The choice of coating(s) is dependent on the environment that the device(s) will be exposed to. We have defined four(4) classes of environments: Class I(moderate temperature/moderate humidity). Class H(high temperature/moderate humidity). Class III(moderate temperature/high humidity). Class IV(high temperature/high humidity). By subjecting the components to adhesion, FTIR, temperature-humidity(TH), pressure cooker(PCT), and electrical tests, we have determined that it is possible to reduce failures 50-70% for organic/inorganic coated components compared to organic coated components. All materials and equipment used are readily available commercially or are standard in most semiconductor fabrication lines. It is estimated that production cost for the developed technology would range from $1-10/module, compared to $20-200 for hermetically sealed packages.

  8. Drosophila subobscura flies adapted to low lead concentration carry no fitness cost

    International Nuclear Information System (INIS)

    Kalajdzic, Predrag; Kenig, Bojan; Andjelkovic, Marko

    2015-01-01

    As a response to the long-term presence of heavy metals in the environment, populations can evolve resistance. Its maintenance may have detrimental effect on population's fitness, causing a fitness cost. Lead is one of the widely distributed elements in the environment exhibiting high toxicity on organisms. By analyzing developmental stages viability and developmental time, we evaluated fitness cost in Drosophila subobscura flies adapted to low lead concentration and control flies derived from the same wild population, as well as their hybrids. Significant changes in specific developmental stages viability were detected in both lines, as well as their hybrids, suggesting complex response to low lead concentration. The results show that a long-term exposure to low lead concentration may have a significant impact on a population's survival, especially in a changing environment conditions. - Highlights: • We analyzed fitness cost in Drosophila subobscura flies reared on lead (Pb) for 37 generations. • Two fitness components, developmental stages viability and developmental time, were analyzed. • A long-term exposure to low lead concentration exhibits a complex adaptation response in D. subobscura flies. • A long-term exposure to low lead concentration decreases viability of population in a changing environment condition. - This study suggests that wild species under a long-term exposure to low concentrations of heavy metals could be in increased risk of population reduction under changing environments

  9. Low-cost hadron colliders at Fermilab: A discussion paper

    International Nuclear Information System (INIS)

    Foster, G.W.; Malamud, E.

    1996-01-01

    New more economic approaches are required to continue the dramatic exponential rise in collider energies as represented by the well known Livingston plot. The old idea of low cost, low field iron dominated magnets in a small diameter pipe may become feasible in the next decade with dramatic recent advances in technology: (1) advanced tunneling technologies for small diameter, non human accessible tunnels, (2) accurate remote guidance systems for tunnel survey and boring machine steering, (3) high T c superconductors operating at liquid N 2 or liquid H 2 temperatures, (4) industrial applications of remote manipulation and robotics, (5) digitally multiplexed electronics to minimize cables, (6) achievement of high luminosities in p-p and p-anti P colliders. The goal of this paper is to stimulate continuing discussions on approaches to this new collider and to identify critical areas needing calculations, construction of models, proof of principle experiments, and full scale prototypes in order to determine feasibility and arrive at cost estimates

  10. A low cost PSD-based monocular motion capture system

    Science.gov (United States)

    Ryu, Young Kee; Oh, Choonsuk

    2007-10-01

    This paper describes a monocular PSD-based motion capture sensor to employ with commercial video game systems such as Microsoft's XBOX and Sony's Playstation II. The system is compact, low-cost, and only requires a one-time calibration at the factory. The system includes a PSD(Position Sensitive Detector) and active infrared (IR) LED markers that are placed on the object to be tracked. The PSD sensor is placed in the focal plane of a wide-angle lens. The micro-controller calculates the 3D position of the markers using only the measured intensity and the 2D position on the PSD. A series of experiments were performed to evaluate the performance of our prototype system. From the experimental results we see that the proposed system has the advantages of the compact size, the low cost, the easy installation, and the high frame rates to be suitable for high speed motion tracking in games.

  11. A Low Cost Sensor Controller for Health Monitoring

    Science.gov (United States)

    Birbas, M.; Petrellis, N.; Gioulekas, F.

    2015-09-01

    Aging population can benefit from health care systems that allow their health and daily life to be monitored by expert medical staff. Blood pressure, temperature measurements or more advanced tests like Electrocardiograms (ECG) can be ordered through such a healthcare system while urgent situations can be detected and alleviated on time. The results of these tests can be stored with security in a remote cloud or database. Such systems are often used to monitor non-life threatening patient health problems and their advantage in lowering the cost of the healthcare services is obvious. A low cost commercial medical sensor kit has been used in the present work, trying to improve the accuracy and stability of the sensor measurements, the power consumption, etc. This Sensor Controller communicates with a Gateway installed in the patient's residence and a tablet or smart phone used for giving instructions to the patient through a comprehensive user interface. A flexible communication protocol has been defined supporting any short or long term sensor sampling scenario. The experimental results show that it is possible to achieve low power consumption by applying apropriate sleep intervals to the Sensor Controller and by deactivating periodically some of its functionality.

  12. Free-floating epithelial micro-tissue arrays: a low cost and versatile technique.

    Science.gov (United States)

    Flood, P; Alvarez, L; Reynaud, E G

    2016-10-11

    Three-dimensional (3D) tissue models are invaluable tools that can closely reflect the in vivo physiological environment. However, they are usually difficult to develop, have a low throughput and are often costly; limiting their utility to most laboratories. The recent availability of inexpensive additive manufacturing printers and open source 3D design software offers us the possibility to easily create affordable 3D cell culture platforms. To demonstrate this, we established a simple, inexpensive and robust method for producing arrays of free-floating epithelial micro-tissues. Using a combination of 3D computer aided design and 3D printing, hydrogel micro-moulding and collagen cell encapsulation we engineered microenvironments that consistently direct the growth of micro-tissue arrays. We described the adaptability of this technique by testing several immortalised epithelial cell lines (MDCK, A549, Caco-2) and by generating branching morphology and micron to millimetre scaled micro-tissues. We established by fluorescence and electron microscopy that micro-tissues are polarised, have cell type specific differentiated phenotypes and regain native in vivo tissue qualities. Finally, using Salmonella typhimurium we show micro-tissues display a more physiologically relevant infection response compared to epithelial monolayers grown on permeable filter supports. In summary, we have developed a robust and adaptable technique for producing arrays of epithelial micro-tissues. This in vitro model has the potential to be a valuable tool for studying epithelial cell and tissue function/architecture in a physiologically relevant context.

  13. Novel Low Cost, High Reliability Wind Turbine Drivetrain

    Energy Technology Data Exchange (ETDEWEB)

    Chobot, Anthony; Das, Debarshi; Mayer, Tyler; Markey, Zach; Martinson, Tim; Reeve, Hayden; Attridge, Paul; El-Wardany, Tahany

    2012-09-13

    Clipper Windpower, in collaboration with United Technologies Research Center, the National Renewable Energy Laboratory, and Hamilton Sundstrand Corporation, developed a low-cost, deflection-compliant, reliable, and serviceable chain drive speed increaser. This chain and sprocket drivetrain design offers significant breakthroughs in the areas of cost and serviceability and addresses the key challenges of current geared and direct-drive systems. The use of gearboxes has proven to be challenging; the large torques and bending loads associated with use in large multi-MW wind applications have generally limited demonstrated lifetime to 8-10 years [1]. The large cost of gearbox replacement and the required use of large, expensive cranes can result in gearbox replacement costs on the order of $1M, representing a significant impact to overall cost of energy (COE). Direct-drive machines eliminate the gearbox, thereby targeting increased reliability and reduced life-cycle cost. However, the slow rotational speeds require very large and costly generators, which also typically have an undesirable dependence on expensive rare-earth magnet materials and large structural penalties for precise air gap control. The cost of rare-earth materials has increased 20X in the last 8 years representing a key risk to ever realizing the promised cost of energy reductions from direct-drive generators. A common challenge to both geared and direct drive architectures is a limited ability to manage input shaft deflections. The proposed Clipper drivetrain is deflection-compliant, insulating later drivetrain stages and generators from off-axis loads. The system is modular, allowing for all key parts to be removed and replaced without the use of a high capacity crane. Finally, the technology modularity allows for scalability and many possible drivetrain topologies. These benefits enable reductions in drivetrain capital cost by 10.0%, levelized replacement and O&M costs by 26.7%, and overall cost of

  14. Depleted-heterojunction colloidal quantum dot photovoltaics employing low-cost electrical contacts

    KAUST Repository

    Debnath, Ratan

    2010-01-01

    With an aim to reduce the cost of depleted-heterojunction colloidal quantum dot solar cells, we describe herein a strategy that replaces costly Au with a low-cost Ni-based Ohmic contact. The resultant devices achieve 3.5% Air Mass 1.5 power conversion efficiency. Only by incorporating a 1.2-nm-thick LiF layer between the PbS quantum dot film and Ni, we were able to prevent undesired reactions and degradation at the metal-semiconductor interface. © 2010 American Institute of Physics.

  15. Cost estimating Brayton and Stirling engines

    Science.gov (United States)

    Fortgang, H. R.

    1980-01-01

    Brayton and Stirling engines were analyzed for cost and selling price for production quantities ranging from 1000 to 400,000 units per year. Parts and components were subjected to indepth scrutiny to determine optimum manufacturing processes coupled with make or buy decisions on materials and small parts. Tooling and capital equipment costs were estimated for each detail and/or assembly. For low annual production volumes, the Brayton engine appears to have a lower cost and selling price than the Stirling Engine. As annual production quantities increase, the Stirling becomes a lower cost engine than the Brayton. Both engines could benefit cost wise if changes were made in materials, design and manufacturing process as annual production quantities increase.

  16. Ultra High Brightness/Low Cost Fiber Coupled Packaging, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — High peak power, high efficiency, high reliability lightweight, low cost QCW laser diode pump modules with up to 1000W of QCW output become possible with nLight's...

  17. Low-cost low-enthalpy geothermal heat for freshwater production: Innovative applications using thermal desalination processes

    KAUST Repository

    Bundschuh, Jochen; Ghaffour, NorEddine; Mahmoudi, Hacè ne; Goosen, Mattheus F A; Mushtaq, Shahbaz; Hoinkis, Jan

    2015-01-01

    The study is dedicated to exploring different types of low-cost low-enthalpy geothermal and their potential integration with conventional thermal-based water desalination and treatment technologies to deliver energy efficient, environmentally friendly solutions for water desalination and treatment, addressing global water crises. Our in-depth investigation through reviews of various low-enthalpy geothermal and conventional thermal-based technologies suggest that the geothermal option is superior to the solar option if low-cost geothermal heat is available because it provides a constant heat source in contrast to solar. Importantly, the stable heat source further allows up-scaling (> 1000 m3/day), which is not currently possible with solar. Solar-geothermal hybrid constellations may also be suitable in areas where both sources are available. The review also discovers that the innovative Membrane distillation (MD) process is very promising as it can be used for many different water compositions, salinity and temperature ranges. Either the geothermal water itself can be desalinated/treated or the geothermal heat can be used to heat feed water from other sources using heat exchangers. However, there are only few economic analyses for large-scale MD units and these are based on theoretical models using often uncertain assumptions resulting in a large variety of results.

  18. Low-cost low-enthalpy geothermal heat for freshwater production: Innovative applications using thermal desalination processes

    KAUST Repository

    Bundschuh, Jochen

    2015-03-01

    The study is dedicated to exploring different types of low-cost low-enthalpy geothermal and their potential integration with conventional thermal-based water desalination and treatment technologies to deliver energy efficient, environmentally friendly solutions for water desalination and treatment, addressing global water crises. Our in-depth investigation through reviews of various low-enthalpy geothermal and conventional thermal-based technologies suggest that the geothermal option is superior to the solar option if low-cost geothermal heat is available because it provides a constant heat source in contrast to solar. Importantly, the stable heat source further allows up-scaling (> 1000 m3/day), which is not currently possible with solar. Solar-geothermal hybrid constellations may also be suitable in areas where both sources are available. The review also discovers that the innovative Membrane distillation (MD) process is very promising as it can be used for many different water compositions, salinity and temperature ranges. Either the geothermal water itself can be desalinated/treated or the geothermal heat can be used to heat feed water from other sources using heat exchangers. However, there are only few economic analyses for large-scale MD units and these are based on theoretical models using often uncertain assumptions resulting in a large variety of results.

  19. A low-cost vector processor boosting compute-intensive image processing operations

    Science.gov (United States)

    Adorf, Hans-Martin

    1992-01-01

    Low-cost vector processing (VP) is within reach of everyone seriously engaged in scientific computing. The advent of affordable add-on VP-boards for standard workstations complemented by mathematical/statistical libraries is beginning to impact compute-intensive tasks such as image processing. A case in point in the restoration of distorted images from the Hubble Space Telescope. A low-cost implementation is presented of the standard Tarasko-Richardson-Lucy restoration algorithm on an Intel i860-based VP-board which is seamlessly interfaced to a commercial, interactive image processing system. First experience is reported (including some benchmarks for standalone FFT's) and some conclusions are drawn.

  20. Low Cost Advanced Thermoelectric (TE) Technology for Automotive Waste Heat Recovery

    Science.gov (United States)

    Meisner, G. P.

    2014-03-01

    Low cost, fully integrated TE generators (TEGs) to recover waste heat from vehicle exhaust will reduce transportation sector energy consumption and emissions. TEGs will be the first application of high-temperature TE materials for high-volume use and establish new industrial sectors with scaled up production capability of TEG materials and components. We will create a potential supply chain for practical automotive TEGs and identify manufacturing and assembly processes for large scale production of TEG materials and components. Our work focusses on several innovative R&D paths: (1) enhanced TE material performance by doping and compositional tuning, (2) optimized TE material fabrication and processing to reduce thermal conductivity and improve fracture strength, (3) high volume production for successful skutterudite commercialization, (4) new material, nanostructure, and nanoscale approaches to reduce thermal interface and electrical contact resistances, (5) innovative heat exchangers for high efficiency heat flows and optimum temperature profiles despite highly variable exhaust gas operating conditions, (6) new modeling and simulation tools, and (7) inexpensive materials for thermal insulation and coatings for TE encapsulation. Recent results will be presented. Supported by the U.S. DOE Vehicle Technology Program.

  1. A low cost microwave synthesis method for preparation of gold nanoparticles

    International Nuclear Information System (INIS)

    Ngo Vo Ke Thanh; Lam Quang Vinh; Nguyen Dang Giang; Huynh Thanh Dat

    2014-01-01

    The gold nanoparticles (GNPs) in 15-20 nm size range have attention for fabrication of smart sensing devices in biomedical sciences as diagnostic tools. Citrate capped GNPs are negatively charged, which can be exploited for electrostatic interactions with some positively charged biomolecules like antibody. In this study, we are developing a low-cost technique by using a common microwave system with medium power for synthesizing gold nanoparticles with using sodium citrate (Na 3 Ct) reduction in chloroauric acid (HAuCl 4 .3H 2 O). It was found that the comparing with normal thermal method, the reaction by the microwave irradiation was much faster. Besides, the effects the sodium citrate concentration and optical properties of gold nanoparticles were studied. The optical properties of gold nanoparticles suspension were characterized by using transmission electron microscopy (TEM), X-ray diffraction (XRD), and UV-Vis absorption spectroscopy (UV-Vis). Maximum absorbance wavelengths (λ max ) for gold nanoparticles are ∼ 518-524 nm with the size of 12-25 nm. The size of gold nanoparticles decreases with increasing concentration of sodium citrate. Besides, the morphology of gold nanoparticles have a spherical shape with face-centered-cubic (fcc) crystalline structure. (author)

  2. Návrh marketingové strategie low cost letecké společnosti

    OpenAIRE

    Khomutova, Sofia

    2016-01-01

    My Master thesis focuses on the design of the marketing strategy of a low-cost airline SparrowJet. The first chapter of the theoretical parts contains the required basics of theoretical information necessary to develop a marketing plan. In the second chapter is an analysis of the air transportation market with an emphasis on the low-cost segment. The final chapter of the theoretical part is dedicated to the marketing mix in the transportation. The practical part of my thesis begins with the s...

  3. Development and Performance Evaluation of a Low Cost Waste ...

    African Journals Online (AJOL)

    The design, development and performance evaluation of a low cost waste-water treatment plant had been carried out. The aim was to harness the usefulness of waste-waters from residential, institutional and commercial sources. The facultative lagoon method of waste-water treatment was adopted. Biological analysis of ...

  4. Towards low-cost gigabit wireless systems at 60 GHz

    NARCIS (Netherlands)

    Yang, Haibing

    2008-01-01

    The world-wide availability of the huge amount of license-free spectral space in the 60 GHz band provides wide room for gigabit-per-second (Gb/s) wireless applications. A commercial (read: low-cost) 60-GHz transceiver will, however, provide limited system performance due to the stringent link budget

  5. Mobile 3d Mapping with a Low-Cost Uav System

    Science.gov (United States)

    Neitzel, F.; Klonowski, J.

    2011-09-01

    In this contribution it is shown how an UAV system can be built at low costs. The components of the system, the equipment as well as the control software are presented. Furthermore an implemented programme for photogrammetric flight planning and its execution are described. The main focus of this contribution is on the generation of 3D point clouds from digital imagery. For this web services and free software solutions are presented which automatically generate 3D point clouds from arbitrary image configurations. Possibilities of georeferencing are described whereas the achieved accuracy has been determined. The presented workflow is finally used for the acquisition of 3D geodata. On the example of a landfill survey it is shown that marketable products can be derived using a low-cost UAV.

  6. Offset Printing Plate Quality Sensor on a Low-Cost Processor

    Directory of Open Access Journals (Sweden)

    Francisco Tirado

    2013-10-01

    Full Text Available The aim of this work is to develop a microprocessor-based sensor that measures the quality of the offset printing plate through the introduction of different image analysis applications. The main features of the presented system are the low cost, the low amount of power consumption, its modularity and easy integration with other industrial modules for printing plates, and its robustness against noise environments. For the sake of clarity, a viability analysis of previous software is presented through different strategies, based on dynamic histogram and Hough transform. This paper provides performance and scalability data compared with existing costly commercial devices. Furthermore, a general overview of quality control possibilities for printing plates is presented and could be useful to a system where such controls are regularly conducted.

  7. Low-Cost Ultra-High Spatial and Temporal Resolution Mapping of Intertidal Rock Platforms

    Science.gov (United States)

    Bryson, M.; Johnson-Roberson, M.; Murphy, R.

    2012-07-01

    Intertidal ecosystems have primarily been studied using field-based sampling; remote sensing offers the ability to collect data over large areas in a snapshot of time which could compliment field-based sampling methods by extrapolating them into the wider spatial and temporal context. Conventional remote sensing tools (such as satellite and aircraft imaging) provide data at relatively course, sub-meter resolutions or with limited temporal resolutions and relatively high costs for small-scale environmental science and ecology studies. In this paper, we describe a low-cost, kite-based imaging system and photogrammetric pipeline that was developed for constructing highresolution, 3D, photo-realistic terrain models of intertidal rocky shores. The processing pipeline uses automatic image feature detection and matching, structure-from-motion and photo-textured terrain surface reconstruction algorithms that require minimal human input and only a small number of ground control points and allow the use of cheap, consumer-grade digital cameras. The resulting maps combine colour and topographic information at sub-centimeter resolutions over an area of approximately 100m, thus enabling spatial properties of the intertidal environment to be determined across a hierarchy of spatial scales. Results of the system are presented for an intertidal rock platform at Cape Banks, Sydney, Australia. Potential uses of this technique include mapping of plant (micro- and macro-algae) and animal (e.g. gastropods) assemblages at multiple spatial and temporal scales.

  8. Rapid Mapping for Built Heritage at Risk Using Low-Cost and Cots Sensors. a Test in the Duomo Vecchio of San Severino Marche

    Science.gov (United States)

    Calantropio, A.; Colucci, E.; Teppati Losè, L.

    2017-11-01

    In the last years, the researchers in the field of Geomatics have focused their attention in the experimentation and validation of new methodologies and techniques, stressing especially the potential of low-cost and COTS (Commercial Off The Shelf) solutions and sensors. In particular, these tools have been used with purposes of rapid mapping in different contexts (ranging from the construction industry, environmental monitoring, mining activities, etc.). The Built Heritage, due to its intrinsic nature of endangered artefact, can largely benefit from the technological and methodological innovations in this research field. The contribute presented in this paper will highlight these main topics: the rapid mapping of the Built Heritage (in particular the one subjected to different types of risk) using low-cost and COTS solutions. Different sensors and techniques were chosen to be evaluated on a specific test site: the Duomo Vecchio of San Severino Marche (MC - Italy), that was partially affected by the earthquake swarm that hit the area of Central Italy starting from the 24th of August 2016. One of the main aims of this work is to demonstrate how low-cost and COTS sensors can contribute to the documentation of the Built Heritage for its safeguard, for damage assessment in case of disastrous events and operations of restoration and preservation.

  9. Soluble protein isolated from low cost fish and fish wastes

    OpenAIRE

    Lekshmy Nair, A.; Gopakumar, K.

    1982-01-01

    The method of preparation, composition, amino acid content, protein efficiency ratio and areas of possible application of water soluble protein isolates from low cost fish and fish wastes are discussed in detail in this communication.

  10. Measuring In-Flight Angular Motion With a Low-Cost Magnetometer

    National Research Council Canada - National Science Library

    Harkins, Thomas E; Wilson, Michael J

    2007-01-01

    A technique for obtaining pitch, yaw, and roll rates of a projectile from a single, low-cost, commercial off-the-shelf magnetometer has been developed at the Advanced Munitions Concepts Branch of the U.S...

  11. A low-cost AFM setup with an interferometer for undergraduates and secondary-school students

    International Nuclear Information System (INIS)

    Bergmann, Antje; Feigl, Daniela; Kuhn, David; Schaupp, Manuel; Quast, Günter; Busch, Kurt; Eichner, Ludwig; Schumacher, Jens

    2013-01-01

    Atomic force microscopy (AFM) is an important tool in nanotechnology. This method makes it possible to observe nanoscopic surfaces beyond the resolution of light microscopy. In order to provide undergraduate and secondary-school students with insights into this world, we have developed a very robust low-cost AFM setup with a Fabry–Perot interferometer as a detecting device. This setup is designed to be operated almost completely manually and its simplicity gives access to a profound understanding of the working principle. Our AFM is operated in a constant height mode, i.e. the topography of the sample surface is represented directly by the deflection of the cantilever. Thus, the measuring procedure can be understood even by secondary-school students; furthermore, it is the method with the lowest cost, totalling not more than 10–15 k Euros. Nevertheless, we are able to examine a large variety of sample topographies such as CD and DVD surfaces, IC structures, blood cells, butterfly wings or moth eyes. Furthermore, force–distance curves can be recorded and the tensile moduli of some materials can be evaluated. We present our setup in detail and describe its working principles. In addition, we show various experiments which have already been performed by students. (paper)

  12. Development of a Low Cost MQL Setup for Turning Operations

    OpenAIRE

    Islam Sumaiya; Khandoker Noman; Izham Mohamad; Azizi Tengku; Debnath Sujan

    2017-01-01

    In this study, the effect of MQL application on the tool wear, surface roughness and chip formation in turning Aluminum alloy 6061 is investigated. Experiments were carried out by plain turning of an Aluminum bar with varying depth of cut, cutting speeds (spindle speed) and cutting environments (Dry, Wet and MQL). A newly designed, cost efficient and portable MQL setup was developed for this study. For each experimental trial, five passes were carried out in order to promote the formation of ...

  13. Waste Management Facilities cost information for mixed low-level waste. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Shropshire, D.; Sherick, M.; Biadgi, C.

    1995-06-01

    This report contains preconceptual designs and planning level life-cycle cost estimates for managing mixed low-level waste. The report`s information on treatment, storage, and disposal modules can be integrated to develop total life-cycle costs for various waste management options. A procedure to guide the US Department of Energy and its contractor personnel in the use of cost estimation data is also summarized in this report.

  14. Comparison of low-cost and engineered materials for phosphorus removal from organic-rich surface water.

    Science.gov (United States)

    Boyer, Treavor H; Persaud, Amar; Banerjee, Poulomi; Palomino, Pedro

    2011-10-15

    Excess phosphorus (P) in lakes and rivers remains a major water quality problem on a global scale. As a result, new materials and innovative approaches to P remediation are required. Natural materials and waste byproduct materials from industrial processes have the potential to be effective materials for P removal from surface water. Advantages of natural and waste byproduct materials include their low-cost, abundant supply, and minimal preparation, especially compared with engineered materials, such as ion exchange resins and polymeric adsorbents. As a result, natural and waste byproduct materials are commonly referred to as low-cost materials. Despite the potential advantages of low-cost materials, there are critical gaps in knowledge that are preventing their effective use. In particular, there are limited data on the performance of low-cost materials in surface waters that have high concentrations of natural organic matter (NOM), and there are no systematic studies that track the changes in water chemistry following treatment with low-cost materials or compare their performance with engineered materials. Accordingly, the goal of this work was to evaluate and compare the effectiveness of low-cost and engineered materials for P removal from NOM-rich surface water. Seven low-cost materials and three engineered materials were evaluated using jar tests and mini-column experiments. The test water was a surface water that had a total P concentration of 132-250 μg P/L and a total organic carbon concentration of 15-32 mg C/L. Alum sludge, a byproduct of drinking water treatment, and a hybrid anion exchange resin loaded with nanosize iron oxide were the best performing materials in terms of selective P removal in the presence of NOM and minimum undesirable secondary changes to the water chemistry. Copyright © 2011 Elsevier Ltd. All rights reserved.

  15. A low-cost Raman spectrometer design used to study Raman ...

    Indian Academy of Sciences (India)

    Unknown

    The paper discusses the design of a low cost Raman spectrometer. ... system. We observe both the radial-breathing mode (RBM) and the tangential mode ... broadened due to the inherent tube diameter distribution present in the material.

  16. Energy Savings of Low-E Storm Windows and Panels across US Climate Zones

    Energy Technology Data Exchange (ETDEWEB)

    Culp, Thomas D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Cort, Katherine A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-10-01

    This report builds off of previous modeling work related to low-e storm windows used to create a "Database of U.S. Climate-Based Analysis for Low-E Storm Windows." This work updates similar studies using new fuel costs and examining the separate contributions of reduced air leakage and reduced coefficients of overall heat transfer and solar heat gain. In this report we examine the energy savings and cost effectiveness of low-E storm windows in residential homes across a broad range of U.S. climates, excluding the impact from infiltration reductions, which tend to vary using the National Energy Audit Tool (NEAT) and RESFEN model calculations. This report includes a summary of the results, NEAT and RESFEN background, methodology, and input assumptions, and an appendix with detailed results and assumptions by climate zone.

  17. Near net shape, low cost ceramic valves for advanced engine applications

    Energy Technology Data Exchange (ETDEWEB)

    Pidria, M.; Merlone, E.; Parussa, F. [Fiat Research Centre, Orbassano (Italy); Handelsman, J.; Gorodnev, A. [Ceracom Materials Ltd., Yavneh (Israel)

    2003-07-01

    Future gasoline and diesel engines with electro-hydraulic or electro-mechanical valve control systems require the development of lighter valves to achieve the best results in terms of increased performances, lower fuel consumption and overall efficiency. Ceramic materials can adequately satisfy the required mechanical and thermal properties, nevertheless they still lack as far as manufacturing costs are concerned. Objective of the work was the development of a low-cost forming and sintering process, to produce near-net shape ceramic valves thus requiring very low finishing operations and significantly minimizing material waste. Between available technical ceramic materials, silicon nitride has been chosen to replace conventional steels and Ni-based alloys for the exhaust valves application. The work was then devoted to (i) the selection of the best starting materials composition, taking into account the requirements of a cost effective and high volume production, (ii) the development of an innovative pressure-injection molding process to produce near-net shape parts via a thermosetting feedstock and (iii) the optimization of a proper pressure-less sintering route to obtain cost-competitive, real scale components with adequate final density and mechanical properties. (orig.)

  18. Nested Interrupt Analysis of Low Cost and High Performance Embedded Systems Using GSPN Framework

    Science.gov (United States)

    Lin, Cheng-Min

    Interrupt service routines are a key technology for embedded systems. In this paper, we introduce the standard approach for using Generalized Stochastic Petri Nets (GSPNs) as a high-level model for generating CTMC Continuous-Time Markov Chains (CTMCs) and then use Markov Reward Models (MRMs) to compute the performance for embedded systems. This framework is employed to analyze two embedded controllers with low cost and high performance, ARM7 and Cortex-M3. Cortex-M3 is designed with a tail-chaining mechanism to improve the performance of ARM7 when a nested interrupt occurs on an embedded controller. The Platform Independent Petri net Editor 2 (PIPE2) tool is used to model and evaluate the controllers in terms of power consumption and interrupt overhead performance. Using numerical results, in spite of the power consumption or interrupt overhead, Cortex-M3 performs better than ARM7.

  19. Construction Costs Assessment of Structural Systems for Low-Rise and Social Welfare Housing

    Directory of Open Access Journals (Sweden)

    Carrillo Julián

    2015-09-01

    Full Text Available A comparative analysis of the costs related to the construction of low-rise, low-cost and social welfare housing was carried out. The study included three of the most commonly used structural systems for low-rise housing in Latin America, such as the traditional system of confined masonry walls, concrete walls conventionally reinforced with welded-wire meshes and concrete walls reinforced with steel fiber. The cost comparison was carried out by budgets analysis, which were performed based on construction quantities, unit prices and particular items for each structural system. It was found in the study that, from an economic point of view, the systems of concrete walls reinforced with welded-wire meshes or steel fibers are more advantageous than confined masonry systems. In addition, the integral comparison of the three structural systems demonstrates that the industrialized system of steel fiber reinforced concrete walls allows obtaining greater advantages of cleaning and sustainability, faster construction, lower cost and a more attractive scenario for builders investing in such projects.

  20. A systematic review of the cost and cost-effectiveness of electronic discharge communications.

    Science.gov (United States)

    Sevick, Laura K; Esmail, Rosmin; Tang, Karen; Lorenzetti, Diane L; Ronksley, Paul; James, Matthew; Santana, Maria; Ghali, William A; Clement, Fiona

    2017-07-02

    The transition between acute care and community care can be a vulnerable period in a patients' treatment due to the potential for postdischarge adverse events. The vulnerability of this period has been attributed to factors related to the miscommunication between hospital-based and community-based physicians. Electronic discharge communication has been proposed as one solution to bridge this communication gap. Prior to widespread implementation of these tools, the costs and benefits should be considered. To establish the cost and cost-effectiveness of electronic discharge communications compared with traditional discharge systems for individuals who have completed care with one provider and are transitioning care to a new provider. We conducted a systematic review of the published literature, using best practices, to identify economic evaluations/cost analyses of electronic discharge communication tools. Inclusion criteria were: (1) economic analysis and (2) electronic discharge communication tool as the intervention. Quality of each article was assessed, and data were summarised using a component-based analysis. One thousand unique abstracts were identified, and 57 full-text articles were assessed for eligibility. Four studies met final inclusion criteria. These studies varied in their primary objectives, methodology, costs reported and outcomes. All of the studies were of low to good quality. Three of the studies reported a cost-effectiveness measure ranging from an incremental daily cost of decreasing average discharge note completion by 1 day of $0.331 (2003 Canadian), a cost per page per discharge letter of €9.51 and a dynamic net present value of €31.1 million for a 5-year implementation of the intervention. None of the identified studies considered clinically meaningful patient or quality outcomes. Economic analyses of electronic discharge communications are scarcely reported, and with inconsistent methodology and outcomes. Further studies are needed