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Sample records for blastomyces dermatitidis including

  1. Red Fox as Sentinel for Blastomyces dermatitidis, Ontario, Canada

    Science.gov (United States)

    Campbell, G. Douglas; Oesterle, Paul T.; Shirose, Lenny; McEwen, Beverly; Jardine, Claire M.

    2016-01-01

    Blastomyces dermatitidis, a fungus that can cause fatal infection in humans and other mammals, is not readily recoverable from soil, its environmental reservoir. Because of the red fox’s widespread distribution, susceptibility to B. dermatitidis, close association with soil, and well-defined home ranges, this animal has potential utility as a sentinel for this fungus. PMID:27314650

  2. Red Fox as Sentinel for Blastomyces dermatitidis, Ontario, Canada.

    Science.gov (United States)

    Nemeth, Nicole M; Campbell, G Douglas; Oesterle, Paul T; Shirose, Lenny; McEwen, Beverly; Jardine, Claire M

    2016-07-01

    Blastomyces dermatitidis, a fungus that can cause fatal infection in humans and other mammals, is not readily recoverable from soil, its environmental reservoir. Because of the red fox's widespread distribution, susceptibility to B. dermatitidis, close association with soil, and well-defined home ranges, this animal has potential utility as a sentinel for this fungus. PMID:27314650

  3. Detection of two Blastomyces dermatitidis serotypes by exoantigen analysis.

    OpenAIRE

    Kaufman, L.; Standard, P G; Weeks, R J; Padhye, A A

    1983-01-01

    We evaluated the diagnostic value of antibody to Blastomyces dermatitidis A precipitin arcs for identifying B. dermatitidis cultures by the exoantigen technique with 88 isolates from the United States and Canada, 12 from Africa, and 1 each from India and Israel. In addition, we studied 190 mycelial-form isolates of other fungi which could be confused antigenically or morphologically with B. dermatitidis. Antigen extracts from all of the North American isolates, the Indian and Israeli isolates...

  4. Effective method for the heat inactivation of Blastomyces dermatitidis.

    Science.gov (United States)

    Brown, Elizabeth M; McTaggart, Lisa R; Low, Donald E; Richardson, Susan E

    2014-10-01

    Manipulation of Blastomyces dermatitidis requires the use of containment level 3 (CL3) practices. However, access to CL3 laboratories is limited and working conditions are restrictive. We describe the validation of a "heat-killing" method to inactivate B. dermatitidis, thus allowing cellular material to be removed from the CL3 laboratory for subsequent DNA isolation that is suitable for genetic applications. PMID:25049039

  5. Ecologic Niche Modeling of Blastomyces dermatitidis in Wisconsin

    OpenAIRE

    Reed, Kurt D.; Meece, Jennifer K.; Archer, John R.; Peterson, A. Townsend

    2008-01-01

    Background Blastomycosis is a potentially fatal mycosis that is acquired by inhaling infectious spores of Blastomyces dermatitidis present in the environment. The ecology of this pathogen is poorly understood, in part because it has been extremely difficult to identify the niche(s) it occupies based on culture isolation of the organism from environmental samples. Methodology/Principal Findings We investigated the ecology of blastomycosis by performing maximum entropy modeling of exposure site...

  6. Identification of the Mating-Type (MAT) Locus That Controls Sexual Reproduction of Blastomyces dermatitidis

    OpenAIRE

    Li, Wenjun; Sullivan, Thomas D.; Walton, Eric; Averette, Anna Floyd; Sakthikumar, Sharadha; Cuomo, Christina A.; Klein, Bruce S.; Heitman, Joseph

    2013-01-01

    Blastomyces dermatitidis is a dimorphic fungal pathogen that primarily causes blastomycosis in the midwestern and northern United States and Canada. While the genes controlling sexual development have been known for a long time, the genes controlling sexual reproduction of B. dermatitidis (teleomorph, Ajellomyces dermatitidis) are unknown. We identified the mating-type (MAT) locus in the B. dermatitidis genome by comparative genomic approaches. The B. dermatitidis MAT locus resembles those of...

  7. Ecologic niche modeling of Blastomyces dermatitidis in Wisconsin.

    Directory of Open Access Journals (Sweden)

    Kurt D Reed

    Full Text Available BACKGROUND: Blastomycosis is a potentially fatal mycosis that is acquired by inhaling infectious spores of Blastomyces dermatitidis present in the environment. The ecology of this pathogen is poorly understood, in part because it has been extremely difficult to identify the niche(s it occupies based on culture isolation of the organism from environmental samples. METHODOLOGY/PRINCIPAL FINDINGS: We investigated the ecology of blastomycosis by performing maximum entropy modeling of exposure sites from 156 cases of human and canine blastomycosis to provide a regional-scale perspective of the geographic and ecologic distribution of B. dermatitidis in Wisconsin. Based on analysis with climatic, topographic, surface reflectance and other environmental variables, we predicted that ecologic conditions favorable for maintaining the fungus in nature occur predominantly within northern counties and counties along the western shoreline of Lake Michigan. Areas of highest predicted occurrence were often in proximity to waterways, especially in northcentral Wisconsin, where incidence of infection is highest. Ecologic conditions suitable for B. dermatitidis are present in urban and rural environments, and may differ at the extremes of distribution of the species in the state. CONCLUSIONS/SIGNIFICANCE: Our results provide a framework for a more informed search for specific environmental factors modulating B. dermatitidis occurrence and transmission and will be useful for improving public health awareness of relative exposure risks.

  8. Activation, binding, and processing of complement component 3 (C3) by Blastomyces dermatitidis.

    OpenAIRE

    Zhang, M X; B. Klein(Ghent University, Ghent, Belgium)

    1997-01-01

    Complement plays a key role in phagocyte recognition and killing of Blastomyces dermatitidis, but little is known about how complement components interact with the yeast. We report the characteristics of activation, binding, and processing of C3 by B. dermatitidis. In pooled normal human serum (NHS), deposition of C3 on the yeast was detectable within 2 min, whereas in NHS containing MgEGTA, deposition was delayed by 6 min, indicating that the yeast activates C3 by both classical and alternat...

  9. Phylogeographic Analysis of Blastomyces dermatitidis and Blastomyces gilchristii Reveals an Association with North American Freshwater Drainage Basins.

    Science.gov (United States)

    McTaggart, Lisa R; Brown, Elizabeth M; Richardson, Susan E

    2016-01-01

    Blastomyces dermatitidis and Blastomyces gilchristii are dimorphic fungal pathogens that cause serious pulmonary and systemic infections in humans. Although their natural habitat is in the environment, little is known about their specific ecologic niche(s). Here, we analyzed 25 microsatellite loci from 169 strains collected from various regions throughout their known endemic range in North America, representing the largest and most geographically diverse collection of isolates studied to date. Genetic analysis of multilocus microsatellite data divided the strains into four populations of B. dermatitidis and four populations of B. gilchristii. B. dermatitidis isolates were recovered from areas throughout North America, while the B. gilchristii strains were restricted to Canada and some northern US states. Furthermore, the populations of both species were associated with major freshwater drainage basins. The four B. dermatitidis populations were partitioned among (1) the Nelson River drainage basin, (2) the St. Lawrence River and northeast Atlantic Ocean Seaboard drainage basins, (3) the Mississippi River System drainage basin, and (4) the Gulf of Mexico Seaboard and southeast Atlantic Ocean Seaboard drainage basins. A similar partitioning of the B. gilchristii populations was observed among the more northerly drainage basins only. These associations suggest that the ecologic niche where the sexual reproduction, growth, and dispersal of B. dermatitidis and B. gilchristii occur is intimately linked to freshwater systems. For most populations, sexual reproduction was rare enough to produce significant linkage disequilibrium among loci but frequent enough that mating-type idiomorphic ratios were not skewed from 1:1. Furthermore, the evolutionary divergence of B. dermatitidis and B. gilchristii was estimated at 1.9 MYA during the Pleistocene epoch. We suggest that repeated glaciations during the Pleistocene period and resulting biotic refugia may have provided the

  10. Phylogeographic Analysis of Blastomyces dermatitidis and Blastomyces gilchristii Reveals an Association with North American Freshwater Drainage Basins

    Science.gov (United States)

    McTaggart, Lisa R.; Brown, Elizabeth M.; Richardson, Susan E.

    2016-01-01

    Blastomyces dermatitidis and Blastomyces gilchristii are dimorphic fungal pathogens that cause serious pulmonary and systemic infections in humans. Although their natural habitat is in the environment, little is known about their specific ecologic niche(s). Here, we analyzed 25 microsatellite loci from 169 strains collected from various regions throughout their known endemic range in North America, representing the largest and most geographically diverse collection of isolates studied to date. Genetic analysis of multilocus microsatellite data divided the strains into four populations of B. dermatitidis and four populations of B. gilchristii. B. dermatitidis isolates were recovered from areas throughout North America, while the B. gilchristii strains were restricted to Canada and some northern US states. Furthermore, the populations of both species were associated with major freshwater drainage basins. The four B. dermatitidis populations were partitioned among (1) the Nelson River drainage basin, (2) the St. Lawrence River and northeast Atlantic Ocean Seaboard drainage basins, (3) the Mississippi River System drainage basin, and (4) the Gulf of Mexico Seaboard and southeast Atlantic Ocean Seaboard drainage basins. A similar partitioning of the B. gilchristii populations was observed among the more northerly drainage basins only. These associations suggest that the ecologic niche where the sexual reproduction, growth, and dispersal of B. dermatitidis and B. gilchristii occur is intimately linked to freshwater systems. For most populations, sexual reproduction was rare enough to produce significant linkage disequilibrium among loci but frequent enough that mating-type idiomorphic ratios were not skewed from 1:1. Furthermore, the evolutionary divergence of B. dermatitidis and B. gilchristii was estimated at 1.9 MYA during the Pleistocene epoch. We suggest that repeated glaciations during the Pleistocene period and resulting biotic refugia may have provided the

  11. Production and characterization of a hybridoma-derived antibody to Blastomyces dermatitidis.

    OpenAIRE

    Young, K D; Larsh, H W

    1982-01-01

    A hybridoma cell line was isolated which produced monoclonal antibody to one protein component of a yeast-phase cytoplasmic antigenic complex of Blastomyces dermatitidis. The immunoglobulin M antibody product was characterized by immunodiffusion, autoradiography of polyacrylamide gels, and cellulose acetate electrophoresis. By attaching the antibody to an affinity gel, one major protein band was identified by polyacrylamide gel electrophoresis as the antigen for which the antibody was specific.

  12. Population Genetic Structure of Clinical and Environmental Isolates of Blastomyces dermatitidis, Based on 27 Polymorphic Microsatellite Markers ▿ †

    OpenAIRE

    Meece, Jennifer K.; Anderson, Jennifer L.; Fisher, Matthew C; Henk, Daniel A.; Sloss, Brian L; Reed, Kurt D.

    2011-01-01

    Blastomyces dermatitidis, a thermally dimorphic fungus, is the etiologic agent of North American blastomycosis. Clinical presentation is varied, ranging from silent infections to fulminant respiratory disease and dissemination to skin and other sites. Exploration of the population genetic structure of B. dermatitidis would improve our knowledge regarding variation in virulence phenotypes, geographic distribution, and difference in host specificity. The objective of this study was to develop a...

  13. Novel Role for Albumin in Innate Immunity: Serum Albumin Inhibits the Growth of Blastomyces dermatitidis Yeast Form In Vitro

    OpenAIRE

    Giles, Steven; Czuprynski, Charles

    2003-01-01

    In this study we found that serum inhibitory activity against Blastomyces dermatitidis was principally mediated by albumin. This was confirmed in experiments using albumin from several mammalian species. Analbuminemic rat serum did not inhibit B. dermatitidis growth in vivo; however, the addition of albumin restored inhibitory activity. Inhibitory activity does not require albumin domain III and appears to involve binding of a low-molecular-weight yeast-derived growth factor.

  14. Phylogenetic analysis reveals a cryptic species Blastomyces gilchristii, sp. nov. within the human pathogenic fungus Blastomyces dermatitidis.

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    Elizabeth M Brown

    Full Text Available BACKGROUND: Analysis of the population genetic structure of microbial species is of fundamental importance to many scientific disciplines because it can identify cryptic species, reveal reproductive mode, and elucidate processes that contribute to pathogen evolution. Here, we examined the population genetic structure and geographic differentiation of the sexual, dimorphic fungus Blastomyces dermatitidis, the causative agent of blastomycosis. METHODOLOGY/PRINCIPAL FINDINGS: Criteria for Genealogical Concordance Phylogenetic Species Recognition (GCPSR applied to seven nuclear loci (arf6, chs2, drk1, fads, pyrF, tub1, and its-2 from 78 clinical and environmental isolates identified two previously unrecognized phylogenetic species. Four of seven single gene phylogenies examined (chs2, drk1, pyrF, and its-2 supported the separation of Phylogenetic Species 1 (PS1 and Phylogenetic Species 2 (PS2 which were also well differentiated in the concatenated chs2-drk1-fads-pyrF-tub1-arf6-its2 genealogy with all isolates falling into one of two evolutionarily independent lineages. Phylogenetic species were genetically distinct with interspecific divergence 4-fold greater than intraspecific divergence and a high Fst value (0.772, P<0.001 indicative of restricted gene flow between PS1 and PS2. Whereas panmixia expected of a single freely recombining population was not observed, recombination was detected when PS1 and PS2 were assessed separately, suggesting reproductive isolation. Random mating among PS1 isolates, which were distributed across North America, was only detected after partitioning isolates into six geographic regions. The PS2 population, found predominantly in the hyper-endemic regions of northwestern Ontario, Wisconsin, and Minnesota, contained a substantial clonal component with random mating detected only among unique genotypes in the population. CONCLUSIONS/SIGNIFICANCE: These analyses provide evidence for a genetically divergent clade within

  15. Mannose Receptor Is Required for Optimal Induction of Vaccine-Induced T-Helper Type 17 Cells and Resistance to Blastomyces dermatitidis Infection.

    Science.gov (United States)

    Wang, Huafeng; LeBert, Vanessa; Li, Mengyi; Lerksuthirat, Tassanee; Galles, Kevin; Klein, Bruce; Wüthrich, Marcel

    2016-06-01

    We investigated how innate sensing by the mannose receptor (MR) influences the development of antifungal immunity. We demonstrate that MR senses mannan on the surface of attenuated Blastomyces dermatitidis vaccine yeast and that MR(-/-) mice demonstrate impaired vaccine immunity against lethal experimental blastomycosis, compared with wild-type control mice. Using naive Blastomyces-specific transgenic CD4(+) T cells, we found that MR regulates differentiation of naive T cells into T-helper type 17 (Th17) effector cells, which are essential in vaccine immunity against systemic dimorphic fungi. Thus, MR regulates differentiation of Th17 cells and is required to induce vaccine immunity against lethal pulmonary blastomycosis. PMID:26931447

  16. Isolation, purification, and radiolabeling of a novel 120-kD surface protein on Blastomyces dermatitidis yeasts to detect antibody in infected patients.

    OpenAIRE

    Klein, B S; Jones, J M

    1990-01-01

    No well-defined Blastomyces-specific antigens are currently available. We used sodium dodecyl sulfate-polyacrylamide gel electrophoresis and immunoblotting to identify immunologically active molecules in the cell wall of B. dermatitidis. A major immunoreactive 120-kD protein (WI-1) was present in all five strains studied and comprised 5% of the protein in the cell wall extract obtained after freezing and thawing yeast cells. WI-1 was recognized by serum from all 10 patients with blastomycosis...

  17. Isolation, purification, and radiolabeling of a novel 120-kD surface protein on Blastomyces dermatitidis yeasts to detect antibody in infected patients

    International Nuclear Information System (INIS)

    No well-defined Blastomyces-specific antigens are currently available. We used sodium dodecyl sulfate-polyacrylamide gel electrophoresis and immunoblotting to identify immunologically active molecules in the cell wall of B. dermatitidis. A major immunoreactive 120-kD protein (WI-1) was present in all five strains studied and comprised 5% of the protein in the cell wall extract obtained after freezing and thawing yeast cells. WI-1 was recognized by serum from all 10 patients with blastomycosis but by none of those from 5 patients with histoplasmosis. It was purified by electroelution, radiolabeled with 125I, and incorporated into a radioimmunoassay (RIA) for serodiagnosis of blastomycosis. Antibody to WI-1 was detected in 58 (85%) of 68 patients with blastomycosis (geometric mean titer, 1:2,981), in two (3%) of 73 patients with histoplasmosis, coccidioidomycosis, sporotrichosis, or candidiasis (titers, 1:86 and 1:91) and in none of 44 healthy persons. WI-1 was shown to be a surface molecule abundant on B. dermatitidis yeasts that were indirectly stained with serum from a rabbit immunized with WI-1. Approximately 0.93 pg of WI-1 or 4.7 x 10(6) WI-1 molecules were found on the surface of an individual yeast using an antigen-inhibition RIA; none was found on Histoplasma capsulatum or Candida albicans yeasts. We conclude that WI-1 is a novel, immunologically active surface molecule on the invasive form of B. dermatitidis and that WI-1 can be used to reliably detect antibody and study the immunopathogenesis of blastomycosis

  18. Isolation, purification, and radiolabeling of a novel 120-kD surface protein on Blastomyces dermatitidis yeasts to detect antibody in infected patients.

    Science.gov (United States)

    Klein, B S; Jones, J M

    1990-01-01

    No well-defined Blastomyces-specific antigens are currently available. We used sodium dodecyl sulfate-polyacrylamide gel electrophoresis and immunoblotting to identify immunologically active molecules in the cell wall of B. dermatitidis. A major immunoreactive 120-kD protein (WI-1) was present in all five strains studied and comprised 5% of the protein in the cell wall extract obtained after freezing and thawing yeast cells. WI-1 was recognized by serum from all 10 patients with blastomycosis but by none of those from 5 patients with histoplasmosis. It was purified by electroelution, radiolabeled with 125I, and incorporated into a radioimmunoassay (RIA) for serodiagnosis of blastomycosis. Antibody to WI-1 was detected in 58 (85%) of 68 patients with blastomycosis (geometric mean titer, 1:2,981), in two (3%) of 73 patients with histoplasmosis, coccidioidomycosis, sporotrichosis, or candidiasis (titers, 1:86 and 1:91) and in none of 44 healthy persons. WI-1 was shown to be a surface molecule abundant on B. dermatitidis yeasts that were indirectly stained with serum from a rabbit immunized with WI-1. Approximately 0.93 pg of WI-1 or 4.7 x 10(6) WI-1 molecules were found on the surface of an individual yeast using an antigen-inhibition RIA; none was found on Histoplasma capsulatum or Candida albicans yeasts. We conclude that WI-1 is a novel, immunologically active surface molecule on the invasive form of B. dermatitidis and that WI-1 can be used to reliably detect antibody and study the immunopathogenesis of blastomycosis. PMID:2295693

  19. Isolation, purification, and radiolabeling of a novel 120-kD surface protein on Blastomyces dermatitidis yeasts to detect antibody in infected patients

    Energy Technology Data Exchange (ETDEWEB)

    Klein, B.S.; Jones, J.M.

    1990-01-01

    No well-defined Blastomyces-specific antigens are currently available. We used sodium dodecyl sulfate-polyacrylamide gel electrophoresis and immunoblotting to identify immunologically active molecules in the cell wall of B. dermatitidis. A major immunoreactive 120-kD protein (WI-1) was present in all five strains studied and comprised 5% of the protein in the cell wall extract obtained after freezing and thawing yeast cells. WI-1 was recognized by serum from all 10 patients with blastomycosis but by none of those from 5 patients with histoplasmosis. It was purified by electroelution, radiolabeled with 125I, and incorporated into a radioimmunoassay (RIA) for serodiagnosis of blastomycosis. Antibody to WI-1 was detected in 58 (85%) of 68 patients with blastomycosis (geometric mean titer, 1:2,981), in two (3%) of 73 patients with histoplasmosis, coccidioidomycosis, sporotrichosis, or candidiasis (titers, 1:86 and 1:91) and in none of 44 healthy persons. WI-1 was shown to be a surface molecule abundant on B. dermatitidis yeasts that were indirectly stained with serum from a rabbit immunized with WI-1. Approximately 0.93 pg of WI-1 or 4.7 x 10(6) WI-1 molecules were found on the surface of an individual yeast using an antigen-inhibition RIA; none was found on Histoplasma capsulatum or Candida albicans yeasts. We conclude that WI-1 is a novel, immunologically active surface molecule on the invasive form of B. dermatitidis and that WI-1 can be used to reliably detect antibody and study the immunopathogenesis of blastomycosis.

  20. The Dynamic Genome and Transcriptome of the Human Fungal Pathogen Blastomyces and Close Relative Emmonsia.

    Directory of Open Access Journals (Sweden)

    José F Muñoz

    2015-10-01

    Full Text Available Three closely related thermally dimorphic pathogens are causal agents of major fungal diseases affecting humans in the Americas: blastomycosis, histoplasmosis and paracoccidioidomycosis. Here we report the genome sequence and analysis of four strains of the etiological agent of blastomycosis, Blastomyces, and two species of the related genus Emmonsia, typically pathogens of small mammals. Compared to related species, Blastomyces genomes are highly expanded, with long, often sharply demarcated tracts of low GC-content sequence. These GC-poor isochore-like regions are enriched for gypsy elements, are variable in total size between isolates, and are least expanded in the avirulent B. dermatitidis strain ER-3 as compared with the virulent B. gilchristii strain SLH14081. The lack of similar regions in related species suggests these isochore-like regions originated recently in the ancestor of the Blastomyces lineage. While gene content is highly conserved between Blastomyces and related fungi, we identified changes in copy number of genes potentially involved in host interaction, including proteases and characterized antigens. In addition, we studied gene expression changes of B. dermatitidis during the interaction of the infectious yeast form with macrophages and in a mouse model. Both experiments highlight a strong antioxidant defense response in Blastomyces, and upregulation of dioxygenases in vivo suggests that dioxide produced by antioxidants may be further utilized for amino acid metabolism. We identify a number of functional categories upregulated exclusively in vivo, such as secreted proteins, zinc acquisition proteins, and cysteine and tryptophan metabolism, which may include critical virulence factors missed before in in vitro studies. Across the dimorphic fungi, loss of certain zinc acquisition genes and differences in amino acid metabolism suggest unique adaptations of Blastomyces to its host environment. These results reveal the dynamics

  1. Blastomyces: Why Be Dimorphic?

    OpenAIRE

    Baumgardner, Dennis J.

    2016-01-01

    In introducing the infectious disease focus for this edition of the Journal of Patient-Centered Research and Reviews, the author describes the unsolved mysteries surrounding the dimorphic fungus Blastomyces and the related pathogenesis of pulmonary blastomycosis.

  2. Pigmentsynthese bei Exophiala dermatitidis : Einfluss auf Phagozytose und Oxidative Burst

    OpenAIRE

    Heidrich, Franziska Miriam

    2010-01-01

    Indolderivate wurden von der Arbeitsgruppe um Prof. Mayser 1998 erstmals bei der Hefe Malassezia furfur beschrieben, bei der sie vermutlich in einem klinischen Zusammenhang mit der Hautkrankheit Pityriasis versicolor stehen. Im Jahr 2006 konnten Nies et al. solche Indolderivate erstmals bei Exophiala dermatitidis nachweisen. Ziel der vorliegenden Arbeit war die vergleichende Untersuchung der Pigmentspektren verschiedener Stämme von Exophiala dermatitidis und ihre Überprüfung au...

  3. Analyses of black fungi by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS): species-level identification of clinical isolates of Exophiala dermatitidis.

    Science.gov (United States)

    Kondori, Nahid; Erhard, Marcel; Welinder-Olsson, Christina; Groenewald, Marizeth; Verkley, Gerard; Moore, Edward R B

    2015-01-01

    Conventional mycological identifications based on the recognition of morphological characteristics can be problematic. A relatively new methodology applicable for the identification of microorganisms is based on the exploitation of taxon- specific mass patterns recorded from abundant cell proteins directly from whole-cell preparations, using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). This study reports the application of MALDI-TOF MS for the differentiation and identifications of black yeasts, isolated from the respiratory tracts of patients with cystic fibrosis (CF). Initial phenotypic and DNA sequence-based analyses identified these isolates to be Exophiala dermatitidis. The type strains of E. dermatitidis (CBS 207.35(T)) and other species of Exophiala were included in the MALDI-TOF MS analyses to establish the references for comparing the mass spectra of the clinical isolates of Exophiala. MALDI-TOF MS analyses exhibited extremely close relationships among the clinical isolates and with the spectra generated from the type strain of E. dermatitidis. The relationships observed between the E. dermatitidis strains from the MALDI-TOF MS profiling analyses were supported by DNA sequence-based analyses of the rRNA ITS1 and ITS2 regions. These data demonstrated the applicability of MALDI-TOF MS as a reliable, rapid and cost-effective method for the identification of isolates of E. dermatitidis and other clinically relevant fungi and yeasts that typically are difficult to identify by conventional methods. PMID:25790495

  4. Effect of Melanin and Carotenoids of Exophiala (Wangiella) dermatitidis on Phagocytosis, Oxidative Burst, and Killing by Human Neutrophils

    OpenAIRE

    Schnitzler, Norbert; Peltroche-Llacsahuanga, Heidrun; Bestier, Nicole; Zündorf, Josef; Lütticken, Rudolf; Haase, Gerhard

    1999-01-01

    The black yeast Exophiala (Wangiella) dermatitidis is an increasingly recognized pathogen and a leading cause of severe pheohyphomycosis. Melanin is thought to contribute to the virulence of E. dermatitidis. Whereas the synthesis and the redox properties of melanin have been studied intensively, the influence of melanin and carotenoids on the phagocytosis, the oxidative burst, and the killing of E. dermatitidis by human neutrophils has not been studied. To study their effects on these phenome...

  5. Ulcération due to Exophiala dermatitidis

    OpenAIRE

    Gérard, C; Duchesne, Bernard; Hayette, Marie-Pierre; Lavalleye, B.; Marechal-Courtois, C.

    1998-01-01

    Les auteurs présentent un cas d'ulcère cornéen à Exophiala dermatitidis. Ce cas permet d'envisager la classification des mycoses cornéennes ainsi que leur fréquences. L'histoire clinique et l'aspect biomicroscopique permettent de mettre en évidence les critères diagnostiques des infections mycotiques. L'intérêt et la techique des prélèvements seront discutés. l'analyse anatomopathologique après greffe de cornée confirme le diagnostic et nous rappelle la place essentielle de cet examen trop so...

  6. Abhängigkeit der Phagozytose, des Oxidativen Bursts und des Killings durch neutrophile Granulozyten von Melanin und Carotenoiden bei Exophiala dermatitidis

    OpenAIRE

    Schauerte, Nicole Andrea

    2004-01-01

    The black melanized yeast Exophiala dermatitidis is a potentially pathogenic fungus frequently isolated from patients suffering from phaeohyphomycosis. Whereas the synthesis and the redox properties of melanin have been studied intensively, the influence of melanin and carotenoids on the phagocytosis, the oxidative burst and the killing of Exophiala dermatitidis by human neutrophils has not been studied. Using a combination of flow cytometrie, epifluorescence interference contrast microscopy ...

  7. Protein functional analysis data in support of comparative proteomics of the pathogenic black yeast Exophiala dermatitidis under different temperature conditions

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    Donatella Tesei

    2015-12-01

    Full Text Available In the current study a comparative proteomic approach was used to investigate the response of the human pathogen black yeast Exophiala dermatitidis toward temperature treatment. Protein functional analysis – based on cellular process GO terms – was performed on the 32 temperature-responsive identified proteins. The bioinformatics analyses and data presented here provided novel insights into the cellular pathways at the base of the fungus temperature tolerance. A detailed analysis and interpretation of the data can be found in “Proteome of tolerance fine-tuning in the human pathogen black yeast Exophiala dermatitidis” by Tesei et al. (2015 [1].

  8. Vaccine-induced protection against 3 systemic mycoses endemic to North America requires Th17 cells in mice

    OpenAIRE

    Wüthrich, Marcel; Gern, Benjamin; Hung, Chiung Yu; Ersland, Karen; Rocco, Nicole; Pick-Jacobs, John; Galles, Kevin; Filutowicz, Hanna; Warner, Thomas; Evans, Michael; Cole, Garry; Klein, Bruce

    2016-01-01

    Worldwide rates of systemic fungal infections, including three of the major pathogens responsible for such infections in North America (Coccidioides posadasii, Histoplasma capsulatum, and Blastomyces dermatitidis), have soared recently, spurring interest in developing vaccines. The development of Th1 cells is believed to be crucial for protective immunity against pathogenic fungi, whereas the role of Th17 cells is vigorously debated. In models of primary fungal infection, some studies have sh...

  9. Epidemiology and management of invasive fungal infections in immunocompromised hosts

    OpenAIRE

    Leenders, Alexander

    1999-01-01

    textabstractFungal infections in man usually are divided into three categories based upon their major pathophysiological characteristics: superficial and cutaneous, subcutaneous and, systemic infections. The last category consists of two separate entities. First there are the so called "endemic mycoses" caused by dimorphic fungi including Coccidioides immiiis, Paracoccidioides brasiliensis, Histoplasma capsula tum and Blastomyces dermatitidis which occur in patients who live in, or have trave...

  10. Comparative Phylogenomics of Pathogenic and Nonpathogenic Species

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    Emily Whiston; Taylor, John W.

    2016-01-01

    The Ascomycete Onygenales order embraces a diverse group of mammalian pathogens, including the yeast-forming dimorphic fungal pathogens Histoplasma capsulatum, Paracoccidioides spp. and Blastomyces dermatitidis, the dermatophytes Microsporum spp. and Trichopyton spp., the spherule-forming dimorphic fungal pathogens in the genus Coccidioides, and many nonpathogens. Although genomes for all of the aforementioned pathogenic species are available, only one nonpathogen had been sequenced. Here, we...

  11. Adaptation of the black yeast Wangiella dermatitidis to ionizing radiation: molecular and cellular mechanisms.

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    Kelly L Robertson

    Full Text Available Observations of enhanced growth of melanized fungi under low-dose ionizing radiation in the laboratory and in the damaged Chernobyl nuclear reactor suggest they have adapted the ability to survive or even benefit from exposure to ionizing radiation. However, the cellular and molecular mechanism of fungal responses to such radiation remains poorly understood. Using the black yeast Wangiella dermatitidis as a model, we confirmed that ionizing radiation enhanced cell growth by increasing cell division and cell size. Using RNA-seq technology, we compared the transcriptomic profiles of the wild type and the melanin-deficient wdpks1 mutant under irradiation and non-irradiation conditions. It was found that more than 3000 genes were differentially expressed when these two strains were constantly exposed to a low dose of ionizing radiation and that half were regulated at least two fold in either direction. Functional analysis indicated that many genes for amino acid and carbohydrate metabolism and cell cycle progression were down-regulated and that a number of antioxidant genes and genes affecting membrane fluidity were up-regulated in both irradiated strains. However, the expression of ribosomal biogenesis genes was significantly up-regulated in the irradiated wild-type strain but not in the irradiated wdpks1 mutant, implying that melanin might help to contribute radiation energy for protein translation. Furthermore, we demonstrated that long-term exposure to low doses of radiation significantly increased survivability of both the wild-type and the wdpks1 mutant, which was correlated with reduced levels of reactive oxygen species (ROS, increased production of carotenoid and induced expression of genes encoding translesion DNA synthesis. Our results represent the first functional genomic study of how melanized fungal cells respond to low dose ionizing radiation and provide clues for the identification of biological processes, molecular pathways and

  12. New Biosynthetic Step in the Melanin Pathway of Wangiella (Exophiala) dermatitidis: Evidence for 2-Acetyl-1,3,6,8-Tetrahydroxynaphthalene as a Novel Precursor

    Science.gov (United States)

    The predominant cell wall melanin of Wangiella dermatitidis, a black fungal pathogen of humans, is synthesized from 1,8-dihydroxynaphthalene (D2HN). An early precursor, 1,3,6,8-tetrahydroxynaphthalene (T4HN), in the pathway leading to D2HN is reportedly produced as a pentaketide directly by an iter...

  13. Systemic Blastomycosis Diagnosed by Prostate Needle Biopsy

    OpenAIRE

    Neal, Peter M.; Nikolai, Anne

    2008-01-01

    A healthy 51-year-old man presented with a 1-month history of lower urinary tract irritative symptoms. Urinalysis was suggestive of infection, and the patient was treated with multiple antibiotics without relief of symptoms.A urological exam demonstrated abnormal induration of the prostate gland. Biopsy of the prostate gland revealed Blastomyces dermatitidis. In areas where Blastomyces dermatitidis is endemic, clinicians should be aware of the presence of this fungus and possible sites of inf...

  14. Outcomes of persons with blastomycosis involving the central nervous system.

    Science.gov (United States)

    Bush, Jonathan W; Wuerz, Terry; Embil, John M; Del Bigio, Marc R; McDonald, Patrick J; Krawitz, Sherry

    2013-06-01

    Blastomyces dermatitidis is a dimorphic fungus which is potentially life-threatening if central nervous system (CNS) dissemination occurs. Sixteen patients with proven or probable CNS blastomycosis are presented. Median duration of symptoms was 90 days; headache and focal neurologic deficit were the most common presenting symptoms. Magnetic resonance imaging (MRI) consistently demonstrated an abnormality, compared to 58% of computed tomography scans. Tissue culture yielded the pathogen in 71% of histology-confirmed cases. All patients who completed treatment of an amphotericin B formulation and extended azole-based therapy did not relapse. Initial nonspecific symptoms lead to delayed diagnosis of CNS blastomycosis. A high index of suspicion is necessary if there is history of contact with an area where B. dermatitidis is endemic. Diagnostic tests should include MRI followed by biopsy for tissue culture and pathology. Optimal treatment utilizes a lipid-based amphotericin B preparation with an extended course of voriconazole. PMID:23566338

  15. Effects of disrupting the polyketide synthase gene WdPKS1 in Wangiella [Exophiala] dermatitidis on melanin production and resistance to killing by antifungal compounds, enzymatic degradation, and extremes in temperature

    Directory of Open Access Journals (Sweden)

    Mandal Piyali

    2006-06-01

    Full Text Available Abstract Background Wangiella dermatitidis is a human pathogenic fungus that is an etiologic agent of phaeohyphomycosis. W. dermatitidis produces a black pigment that has been identified as a dihydroxynaphthalene melanin and the production of this pigment is associated with its virulence. Cell wall pigmentation in W. dermatitidis depends on the WdPKS1 gene, which encodes a polyketide synthase required for generating the key precursor for dihydroxynaphthalene melanin biosynthesis. Results We analyzed the effects of disrupting WdPKS1 on dihydroxynaphthalene melanin production and resistance to antifungal compounds. Transmission electron microscopy revealed that wdpks1Δ-1 yeast had thinner cell walls that lacked an electron-opaque layer compared to wild-type cells. However, digestion of the wdpks1Δ-1 yeast revealed small black particles that were consistent with a melanin-like compound, because they were acid-resistant, reacted with melanin-binding antibody, and demonstrated a free radical signature by electron spin resonance analysis. Despite lacking the WdPKS1 gene, the mutant yeast were capable of catalyzing the formation of melanin from L-3,4-dihyroxyphenylalanine. The wdpks1Δ-1 cells were significantly more susceptible to killing by voriconazole, amphotericin B, NP-1 [a microbicidal peptide], heat and cold, and lysing enzymes than the heavily melanized parental or complemented strains. Conclusion In summary, W. dermatitidis makes WdPKS-dependent and -independent melanins, and the WdPKS1-dependent deposition of melanin in the cell wall confers protection against antifungal agents and environmental stresses. The biological role of the WdPKS-independent melanin remains unclear.

  16. Systemic blastomycosis in a horse.

    Science.gov (United States)

    Wilson, Julia H; Olson, Erik J; Haugen, Edward W; Hunt, Luanne M; Johnson, Jennifer L; Hayden, David W

    2006-11-01

    Progressive multisystemic disease caused by Blastomyces dermatitidis was diagnosed in a 17-year-old Quarter horse broodmare. The mare had been treated unsuccessfully with antibiotics for mastitis 3 months postpartum. The disease progressed to exudative cutaneous lesions affecting the ventrum, pectoral region, and limbs accompanied by weight loss across several months. Yeast bodies were observed in swabs of the cutaneous exudate, suggesting a clinical diagnosis of blastomycosis. Following referral, pleural effusion, cavitated lung lesions, and hyperproteinemia were identified, and the mare was euthanized because of poor prognosis. Necropsy revealed extensive pyogranulomas in the mammary gland, skin, subcutaneous tissues, and lungs, accompanied by thrombi in major blood vessels of the lungs and hind limbs. Histologically, pyogranulomatous inflammation was evident in many tissues, and fungal organisms were seen in sections of mammary gland, skin, subcutis, pericardium, and lung. Blastomyces dermatitidis was cultured from mammary tissue, lungs, lymph node, and an inguinal abscess. Although blastomycosis is endemic in the area of origin of the mare in northwestern Wisconsin, the disease is extremely rare in horses and hence easily misdiagnosed. Unique features of this case included the extent of mammary gland involvement and the presence of thrombi in multiple sites. PMID:17121096

  17. C-type lectin receptors differentially induce Th17 cells and vaccine immunity to the endemic mycosis of North America

    OpenAIRE

    Wang, Huafeng; LeBert, Vanessa; Hung, Chiung Yu; Galles, Kevin; Saijo, Shinobu; Lin, Xin; Cole, Garry T.; Bruce S Klein; Wüthrich, Marcel

    2014-01-01

    Vaccine immunity to the endemic mycoses of North America requires Th17 cells, but the pattern recognition receptors and signaling pathways that drive these protective responses have not been defined. We show that C-type lectin receptors (CLRs) exert divergent contributions to the development of anti-fungal Th17 cells and vaccine resistance against Blastomyces dermatitidis, Histoplasma capsulatum and Coccidioides posadasii. Acquired immunity to B. dermatitidis requires Dectin-2, whereas vaccin...

  18. Computed Tomographic Scan Evaluation of Pulmonary Blastomycosis

    Directory of Open Access Journals (Sweden)

    Suzanne Ronald

    2009-01-01

    Full Text Available BACKGROUND: Blastomycosis is an uncommon granulomatous pulmonary and extrapulmonary infectious disease caused by the thermally dimorphic fungus Blastomyces dermatitidis. Diagnosis may be delayed or difficult because of varied presentation. The characteristics of blastomycosis on computed tomographic (CT scan of the chest are not well characterized.

  19. Thoracic and abdominal blastomycosis in a horse.

    Science.gov (United States)

    Toribio, R E; Kohn, C W; Lawrence, A E; Hardy, J; Hutt, J A

    1999-05-01

    A 5-year-old Quarter Horse mare was examined because of lethargy, fever, and weight loss of 1 month's duration. Thoracic auscultation revealed decreased lung sounds cranioventrally. Thoracic ultrasonography revealed bilateral anechoic areas with hyperechoic strands, consistent with pleural effusion and fibrin tags. A large amount of free fluid was evident during abdominal ultrasonography. Abnormalities included anemia, hyperproteinemia, hyperglobulinemia, hyperfibrinogenemia, and hypoalbuminemia. Thoracic radiography revealed alveolar infiltrates in the cranial and caudoventral lung fields. A cavitary mass, consistent with an abscess, could be seen caudodorsal to the crura of the diaphragm. Ultrasonographic evaluation of this area revealed a hypoechoic mass with septations. Bilateral thoracocentesis was performed. Bacterial culture of the pleural fluid did not yield growth, but Blastomyces dermatitidis was isolated from pleural fluid, abdominal fluid, and an aspirate of the abscess. The mare was euthanatized, and a diagnosis of thoracic and abdominal blastomycosis was confirmed at necropsy. PMID:10319179

  20. Calnexin induces expansion of antigen-specific CD4(+) T cells that confer immunity to fungal ascomycetes via conserved epitopes.

    Science.gov (United States)

    Wüthrich, Marcel; Brandhorst, Tristan T; Sullivan, Thomas D; Filutowicz, Hanna; Sterkel, Alana; Stewart, Douglas; Li, Mengyi; Lerksuthirat, Tassanee; LeBert, Vanessa; Shen, Zu Ting; Ostroff, Gary; Deepe, George S; Hung, Chiung Yu; Cole, Garry; Walter, Jennifer A; Jenkins, Marc K; Klein, Bruce

    2015-04-01

    Fungal infections remain a threat due to the lack of broad-spectrum fungal vaccines and protective antigens. Recent studies showed that attenuated Blastomyces dermatitidis confers protection via T cell recognition of an unknown but conserved antigen. Using transgenic CD4(+) T cells recognizing this antigen, we identify an amino acid determinant within the chaperone calnexin that is conserved across diverse fungal ascomycetes. Calnexin, typically an ER protein, also localizes to the surface of yeast, hyphae, and spores. T cell epitope mapping unveiled a 13-residue sequence conserved across Ascomycota. Infection with divergent ascomycetes, including dimorphic fungi, opportunistic molds, and the agent causing white nose syndrome in bats, induces expansion of calnexin-specific CD4(+) T cells. Vaccine delivery of calnexin in glucan particles induces fungal antigen-specific CD4(+) T cell expansion and resistance to lethal challenge with multiple fungal pathogens. Thus, the immunogenicity and conservation of calnexin make this fungal protein a promising vaccine target. PMID:25800545

  1. Virulence Factors IN Fungi OF Systemic Mycoses

    OpenAIRE

    Kurokawa, Cilmery Suemi; Sugizaki, Maria Fátima; PERAÇOLI Maria Terezinha Serrão

    1998-01-01

    Pathogenic fungi that cause systemic mycoses retain several factors which allow their growth in adverse conditions provided by the host, leading to the establishment of the parasitic relationship and contributing to disease development. These factors are known as virulence factors which favor the infection process and the pathogenesis of the mycoses. The present study evaluates the virulence factors of pathogenic fungi such as Blastomyces dermatitidis, Coccidioides immitis, Cryptococcus neofo...

  2. Optical modulator including grapene

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Ming; Yin, Xiaobo; Zhang, Xiang

    2016-06-07

    The present invention provides for a one or more layer graphene optical modulator. In a first exemplary embodiment the optical modulator includes an optical waveguide, a nanoscale oxide spacer adjacent to a working region of the waveguide, and a monolayer graphene sheet adjacent to the spacer. In a second exemplary embodiment, the optical modulator includes at least one pair of active media, where the pair includes an oxide spacer, a first monolayer graphene sheet adjacent to a first side of the spacer, and a second monolayer graphene sheet adjacent to a second side of the spacer, and at least one optical waveguide adjacent to the pair.

  3. A few shared up-regulated genes may influence conidia to yeast transformation in dimorphic fungal pathogens.

    Science.gov (United States)

    Kirkland, Theo N

    2016-08-01

    The small number of fungi that commonly cause disease in normal people share the capacity to grow as mycelia in the soil at 25°C and as yeast (or spherules) in mammals at 37°C. This remarkable conversion has long been a topic of interest in medical mycology. The conidia to yeast conversion has been studied by transcription profiling in several fungal species, including Histoplasma capsulatum, Paracoccidioides brasiliensis, Coccidioides spp., Blastomyces dermatitidis, and Talaromyces marneffei One limitation of transcriptional profiling is determining which genes are involved in the process of conversion to yeast as opposed to a result of conversion to yeast. If there are genes that are up-regulated in the yeast phase of more than one dimorphic, pathogenic fungus they might be required for conversion to yeast (or spherules). To address this issue, 24 up-regulated genes common to Coccidioides spp spherules and H. capsulatum yeasts were identified. Four homologs of these genes were also found in P. brasiliensis, B. dermatitidis or T. marneffei genes that were up-regulated in yeast. 4-hydroxyphenylpurvate dioxygenase, a gene involved in tyrosine metabolism and melanin synthesis that has been shown to be required for yeast conversion, is conserved and up-regulated in yeast in all five species. Another up-regulated gene that is conserved in all five species is a MFS sugar porter. These results suggest that a minority of up-regulated yeast (or spherule) genes are conserved across species and raises the possibility that conserved up-regulated genes may be of special interest for differentiation of mycelium into yeast. PMID:27118798

  4. Analytic device including nanostructures

    KAUST Repository

    Di, Fabrizio, E.

    2015-07-02

    A device for detecting an analyte in a sample comprising: an array including a plurality of pixels, each pixel including a nanochain comprising: a first nanostructure, a second nanostructure, and a third nanostructure, wherein size of the first nanostructure is larger than that of the second nanostructure, and size of the second nanostructure is larger than that of the third nanostructure, and wherein the first nanostructure, the second nanostructure, and the third nanostructure are positioned on a substrate such that when the nanochain is excited by an energy, an optical field between the second nanostructure and the third nanostructure is stronger than an optical field between the first nanostructure and the second nanostructure, wherein the array is configured to receive a sample; and a detector arranged to collect spectral data from a plurality of pixels of the array.

  5. Posaconazole: An Update of Its Clinical Use

    Directory of Open Access Journals (Sweden)

    Simon Leung

    2015-10-01

    Full Text Available Posaconazole (PCZ is a relatively new addition to the azole antifungals. It has fungicidal activities against Aspergillus fumigatus, Blastomyces dermatitidis, selected Candida species, Crytopcoccus neoformans, and Trichosporon. PCZ also has fungistatic activities against Candida, Coccidioides, selected Fusarium spp., Histoplasma, Scedosporium and Zygomycetes. In addition, combining the drug with caspofungin or amphotericin B results in a synergistic interaction against A. fumigatus, C. glabrata and C. neoformans. The absorption of PCZ suspension is enhanced when given with food, nutritional supplements, and carbonated beverages. Oral administration of PCZ in divided doses also increases its bioavailability. PCZ has a large volume of distribution and is highly protein bound (>95%. The main elimination route of PCZ is fecal. PCZ is an inhibitor of the CYP3A4 enzyme; therefore, monitoring for drug-drug interactions is warranted with other CYP3A4 substrates/inhibitors/inducers. The most common adverse effects include headache, fatigue, nausea, vomiting and elevated hepatic enzymes. PCZ, with its unique antifungal activities, expands the azole class of antifungal agents. Because of its limit in formulation, PCZ oral suspension is recommended in immunocompromised patients with functional gastrointestinaltracts who fail conventional antifungal therapies or who are suspected to have a breakthrough fungal infection. However, a delayed-release tablet formulation and intravenous (IV injection became available in 2014, expanding the use of PCZ in other patient populations, including individuals who are unable to take oral formulations.

  6. Blastomycosis Presenting as Multiple Splenic Abscesses: Case Report and Review of the Literature

    Directory of Open Access Journals (Sweden)

    Sami Al-Nassar

    2010-01-01

    Full Text Available A 31-year-old Canadian Aboriginal man from northwestern Ontario presented with left upper quadrant pain and a tender left upper quadrant mass. Evaluation with a computed tomography scan showed multiple lesions within the spleen, a collection between the splenic tip and splenic flexure of the colon, and several small adrenal lesions. Computed tomographic-guided needle biopsy showed necrotizing granulomatous inflammation and multinucleated giant cells. Gomori’s methenamine silver stain showed broad-based budding yeast consistent with Blastomyces dermatitidis. Abdominal symptoms resolved after two months of oral itraconazole. Multiple splenic abscesses are a rare presentation of blastomycosis and should be considered in the differential diagnosis of left upper quadrant abdominal pain in a patient with a history of travel or residence in a region endemic for B dermatitidis.

  7. Agents of endemic mycoses

    OpenAIRE

    Matos, Tadeja

    2015-01-01

    Med najpomembnejše povzročitelje endemskih mikoz, za katerimi zbolevajo tudi zdravi posamezniki z normalnim imunskim odgovorom, sodijo Histoplasma capsulatum, Blastomyces dermatitidis, Paracoccidioides brasiliensis in Coccidioides immitis. Za vse naštete glive je značilen temperaturni dimorfizem. Najdemo jih na omejenih geografskih področjih sveta in za okužbamiz njimi zbolevajo ljudje, ki stalno ali začasno živijo na teh področjih. Ker je naravna ekološ ka niša večine povzročiteljev endemski...

  8. Tc17 Cells Mediate Vaccine Immunity against Lethal Fungal Pneumonia in Immune Deficient Hosts Lacking CD4+ T Cells

    OpenAIRE

    Som Gowda Nanjappa; Erika Heninger; Marcel Wüthrich; David Joseph Gasper; Bruce S Klein

    2012-01-01

    Vaccines may help reduce the growing incidence of fungal infections in immune-suppressed patients. We have found that, even in the absence of CD4(+) T-cell help, vaccine-induced CD8(+) T cells persist and confer resistance against Blastomyces dermatitidis and Histoplasma capsulatum. Type 1 cytokines contribute to that resistance, but they also are dispensable. Although the role of T helper 17 cells in immunity to fungi is debated, IL-17 producing CD8(+) T cells (Tc17 cells) have not been inve...

  9. Associação da rifampicina à anfotericina B no tratamento da paracoccidioidomicose: resultados em três pacientes tratados Association of Amphotericin B and Rifampicin in the treatment of paracoccidioidomycosis. Report of efficacy in three cases

    Directory of Open Access Journals (Sweden)

    Bodo Wanke

    1984-08-01

    Full Text Available Trabalhos experimentais demonstraram que a anfotericina B, desorganizando funcionalmente a membrana celular fúngica, permite a penetração da rifampicina no citoplasma e sua conseqüente ação contra Histoplasma capsulatum, Blastomyces dermatitidis e Candida albicans. Com metade das doses habituais' de anfotericina B associada à rifampicina conseguem-se melhores resultados do que com a anfotericina B isoladamente em doses plenas. Os Autores discutem as possíveis aplicações desta associação no tratamento da paracoccidioidomi-cose e apresentam 3 casos desta micose em que a inatividade clínica e micológica só foi obtida após o emprego combinado destas drogas.Experimental data have shown that low concentration of amphotericin B disrupts of the fungal cellular membranes, enhancing entrance of rifampicin into citoplasm, where it acts specifically as an antifungal agent against Histoplasma capsulatum, Blastomyces dermatitidis and Candida albicans. Amphotericin B in half dosage combined with rifampicin is more effective than when used alone in full dosage. The Authors discuss the possible indications of this association in the therapy of paracoccidioidomycosis, and report its efficacy in three cases of this disease only controlled after its use.

  10. Biodiversity conservation including uncharismatic species

    DEFF Research Database (Denmark)

    Muñoz, Joaquin

    2007-01-01

    (Chapron 2006; Schwartz 2006), and the main threats to biodiversity (including invasive species) (Bawa 2006). I suggest, however, that these articles do not really deal with biodiversity. Rather, they all focus on a few obviously charismatic groups (mammals, birds, some plants, fishes, human culture......). Mammals and birds have traditionally been proposed as umbrella or flagship species (‘‘species that needs such large tracts of habitat that saving it will automatically save many other species’’––Simberloff 1998), to identify areas suitable as nature reserves (Kerr 1997; Sergio et al. 2005)....

  11. Theory including future not excluded

    DEFF Research Database (Denmark)

    Nagao, K.; Nielsen, H.B.

    2013-01-01

    We study a complex action theory (CAT) whose path runs over not only past but also future. We show that, if we regard a matrix element defined in terms of the future state at time T and the past state at time TA as an expectation value in the CAT, then we are allowed to have the Heisenberg equation......, Ehrenfest's theorem, and the conserved probability current density. In addition,we showthat the expectation value at the present time t of a future-included theory for large T - t and large t - T corresponds to that of a future-not-included theory with a proper inner product for large t - T. Hence, the CAT...... with future explicitly present in the formalism and influencing in principle the past is not excluded phenomenologically, because the effects are argued to be very small in the present era. Furthermore, we explicitly derive the Hamiltonian for the future state via a path integral, and confirm that it...

  12. Families classification including multiopposition asteroids

    Science.gov (United States)

    Milani, Andrea; Spoto, Federica; Knežević, Zoran; Novaković, Bojan; Tsirvoulis, Georgios

    2016-01-01

    In this paper we present the results of our new classification of asteroid families, upgraded by using catalog with > 500,000 asteroids. We discuss the outcome of the most recent update of the family list and of their membership. We found enough evidence to perform 9 mergers of the previously independent families. By introducing an improved method of estimation of the expected family growth in the less populous regions (e.g. at high inclination) we were able to reliably decide on rejection of one tiny group as a probable statistical fluke. Thus we reduced our current list to 115 families. We also present newly determined ages for 6 families, including complex 135 and 221, improving also our understanding of the dynamical vs. collisional families relationship. We conclude with some recommendations for the future work and for the family name problem.

  13. In Search for Equilibrium: Immunosuppression Versus Opportunistic Infection.

    Science.gov (United States)

    Yousuf, Tariq; Kramer, Jason; Kopiec, Adam; Jones, Brody; Iskandar, Joy; Ahmad, Khansa; Keshmiri, Hesam; Dia, Muhyaldeen

    2016-02-01

    Post-transplant immunosuppression is necessary to prevent organ rejection. Immunosuppression itself can introduce complications arising from opportunistic infections. We present a case of disseminated blastomycosis manifested only as a skin lesion in an asymptomatic patient post-orthotopic heart transplantation. A 64-year-old female who had recently undergone orthotopic heart transplant for end-stage ischemic cardiomyopathy presented for a scheduled routine cardiac biopsy. The patient had no current complaints other than a crusted plaque noticed at her nasal tip. It initially manifested 6 months after surgery as a pimple that she repeatedly tried to manipulate resulting in redness and crust formation. Her immunosuppressive and prophylactic medications included: mycophenolate, tacrolimus, prednisone, bactrim, acyclovir, valganciclovir, pyrimethamine/sulfadiazine, and fluconazole. On physical examination, she was flushed, with a large and exquisitely tender crusted necrotic lesion involving almost the entire half of the nose anteriorly, the left forehead and right side of the neck. She had decreased air entry over the right lung field as well. A computed tomography (CT) image of the chest was ordered to investigate this concerning physical exam finding in the post-transplant state of this patient on immunosuppressive therapy. Chest CT revealed bilateral nodular pulmonary infiltrates with confluence in the posterior right upper lobe. Blood cultures for aerobic and anerobic organisms were negative. Both excisional biopsy of the nasal cutaneous ulcer and bronchial biopsy demonstrated numerous fungal yeast forms morphologically consistent with Blastomyces. Cultures of both specimens grew Blastomyces dermatitidis, with methicillin-resistant Staphylococcus aureus (MRSA) superinfection of the nose. She received 14 days of intravenous (IV) amphotericin B for disseminated blastomycosis and 7 days of IV vancomycin for MRSA. Her symptoms and cutaneous lesions improved and she

  14. Brake assembly including torque monitor

    International Nuclear Information System (INIS)

    This patent describes a brake assembly for selectively braking rotation of an input shaft extending from a control rod drive having a longitudinal centerline axis, the shaft being rotatable for selectively inserting and withdrawing a control rod in a nuclear reactor vessel. It comprises a stationary base; an annular bearing mounted to the base; a brake mounted to the bearing; a backing plate mounted to the bearing; a first braking pad fixedly joined to the backing plate; a rotor disc fixedly connected to the input shaft and disposed adjacent to the first pad; a second braking pad disposed adjacent to the rotor disc; and means for selectively clamping the first and second pads against the rotor disc for braking the input shaft; means for torsionally restraining the brake including: a pin extending outwardly from the backing plate toward the base; and a spring extending from the base to the pin and generally perpendicular to the centerline axis; and means for monitoring the angle for monitoring braking torque capability of the brake

  15. FungalRV: adhesin prediction and immunoinformatics portal for human fungal pathogens

    Directory of Open Access Journals (Sweden)

    Ramachandran Srinivasan

    2011-04-01

    Full Text Available Abstract Background The availability of sequence data of human pathogenic fungi generates opportunities to develop Bioinformatics tools and resources for vaccine development towards benefitting at-risk patients. Description We have developed a fungal adhesin predictor and an immunoinformatics database with predicted adhesins. Based on literature search and domain analysis, we prepared a positive dataset comprising adhesin protein sequences from human fungal pathogens Candida albicans, Candida glabrata, Aspergillus fumigatus, Coccidioides immitis, Coccidioides posadasii, Histoplasma capsulatum, Blastomyces dermatitidis, Pneumocystis carinii, Pneumocystis jirovecii and Paracoccidioides brasiliensis. The negative dataset consisted of proteins with high probability to function intracellularly. We have used 3945 compositional properties including frequencies of mono, doublet, triplet, and multiplets of amino acids and hydrophobic properties as input features of protein sequences to Support Vector Machine. Best classifiers were identified through an exhaustive search of 588 parameters and meeting the criteria of best Mathews Correlation Coefficient and lowest coefficient of variation among the 3 fold cross validation datasets. The "FungalRV adhesin predictor" was built on three models whose average Mathews Correlation Coefficient was in the range 0.89-0.90 and its coefficient of variation across three fold cross validation datasets in the range 1.2% - 2.74% at threshold score of 0. We obtained an overall MCC value of 0.8702 considering all 8 pathogens, namely, C. albicans, C. glabrata, A. fumigatus, B. dermatitidis, C. immitis, C. posadasii, H. capsulatum and P. brasiliensis thus showing high sensitivity and specificity at a threshold of 0.511. In case of P. brasiliensis the algorithm achieved a sensitivity of 66.67%. A total of 307 fungal adhesins and adhesin like proteins were predicted from the entire proteomes of eight human pathogenic fungal

  16. Static, Lightweight Includes Resolution for PHP

    NARCIS (Netherlands)

    Hills, M.A.; Klint, P.; Vinju, J.J.

    2014-01-01

    Dynamic languages include a number of features that are challenging to model properly in static analysis tools. In PHP, one of these features is the include expression, where an arbitrary expression provides the path of the file to include at runtime. In this paper we present two complementary analy

  17. Article Including Environmental Barrier Coating System

    Science.gov (United States)

    Lee, Kang N. (Inventor)

    2015-01-01

    An enhanced environmental barrier coating for a silicon containing substrate. The enhanced barrier coating may include a bond coat doped with at least one of an alkali metal oxide and an alkali earth metal oxide. The enhanced barrier coating may include a composite mullite bond coat including BSAS and another distinct second phase oxide applied over said surface.

  18. Composite Pressure Vessel Including Crack Arresting Barrier

    Science.gov (United States)

    DeLay, Thomas K. (Inventor)

    2013-01-01

    A pressure vessel includes a ported fitting having an annular flange formed on an end thereof and a tank that envelopes the annular flange. A crack arresting barrier is bonded to and forming a lining of the tank within the outer surface thereof. The crack arresting barrier includes a cured resin having a post-curing ductility rating of at least approximately 60% through the cured resin, and further includes randomly-oriented fibers positioned in and throughout the cured resin.

  19. 28 CFR 20.32 - Includable offenses.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Includable offenses. 20.32 Section 20.32 Judicial Administration DEPARTMENT OF JUSTICE CRIMINAL JUSTICE INFORMATION SYSTEMS Federal Systems and Exchange of Criminal History Record Information § 20.32 Includable offenses. (a) Criminal history...

  20. Probable Pulmonary Blastomycosis in a Wild Coyote (Canis latrans

    Directory of Open Access Journals (Sweden)

    Luis E. Rodríguez-Tovar

    2015-01-01

    Full Text Available A female coyote (Canis latrans was fatally injured by a vehicle on a road in San Luis Potosi, Mexico. Because of deteriorating clinical signs, the animal was euthanized. Postmortem examination of the lungs showed numerous small multifocal white nodules (0.5–1 cm diameter disseminated throughout. Histopathologic examination revealed multifocal coalescing granulomas with abundant macrophages, numerous neutrophils, fibroblasts, plasma cells, and lymphocytes. Abundant intracellular and extracellular thick-walled, refractile, spherical yeasts (10–15 μm were observed within the granulomas. The yeasts were intensely PAS-positive, with granular protoplasm. Broad-based single budding yeasts were occasionally present. Based on the microscopic findings of the pulmonary lesions and the morphological features of the organism, a diagnosis of chronic pyogranulomatous pneumonia caused by Blastomyces dermatitidis was made. To our knowledge, the case described herein is the first report of pulmonary blastomycosis in a wild coyote.

  1. Lymphocyte transformation in presumed ocular histoplasmosis

    International Nuclear Information System (INIS)

    Lymphocytes from individuals with inactive macular disciform lesions of presumed ocular histoplasmosis challenged with three histoplasmin antigens incorporated tritiated thymidine at a significantly higher rate than histoplasmin-stimulated lymphocytes of matched control and peripheral scar groups. This finding is consistent with the etiologic association of the disciform ocular syndrome and previous systemic infection with Histoplasma capsulatum. The disciform group had a higher mean response than the other two groups to pokeweed mitogen but not to phytohemagglutinin and had higher mean counts per minute to the specific antigens Toxoplasma gondii, Blastomyces dermatitidis, Cryptococcus neoformans, Mycobacterium tuberculosis, M battery, and M gaus, but not to Candida albicans. These data would suggest that individuals with the disciform lesion of presumed ocular histoplasmosis have a hyperreactive cellular immune response; this response may play an important role in the development of the disciform

  2. Virulence Factors IN Fungi OF Systemic Mycoses

    Directory of Open Access Journals (Sweden)

    KUROKAWA Cilmery Suemi

    1998-01-01

    Full Text Available Pathogenic fungi that cause systemic mycoses retain several factors which allow their growth in adverse conditions provided by the host, leading to the establishment of the parasitic relationship and contributing to disease development. These factors are known as virulence factors which favor the infection process and the pathogenesis of the mycoses. The present study evaluates the virulence factors of pathogenic fungi such as Blastomyces dermatitidis, Coccidioides immitis, Cryptococcus neoformans, Histoplasma capsulatum and Paracoccidioides brasiliensis in terms of thermotolerance, dimorphism, capsule or cell wall components as well as enzyme production. Virulence factors favor fungal adhesion, colonization, dissemination and the ability to survive in hostile environments and elude the immune response mechanisms of the host. Both the virulence factors presented by different fungi and the defense mechanisms provided by the host require action and interaction of complex processes whose knowledge allows a better understanding of the pathogenesis of systemic mycoses.

  3. Haemophilus influenzae Disease (Including Hib) Symptoms

    Science.gov (United States)

    ... is considered invasive. Symptoms of pneumonia usually include: Fever and chills Cough Shortness of breath or difficulty breathing Sweating ... the blood. It can cause symptoms such as: Fever and chills Excessive tiredness Pain in the belly Nausea with ...

  4. What Does Long-Term Care Include?

    Medline Plus

    Full Text Available Video: "What Does Long-Term Care Include?" Long-term care involves a variety of services designed to meet a person's health or personal care needs during a short or long period of ...

  5. Births and deaths including fetal deaths

    Data.gov (United States)

    U.S. Department of Health & Human Services — Access to a variety of United States birth and death files including fetal deaths: Birth Files, 1968-2009; 1995-2005; Fetal death file, 1982-2005; Mortality files,...

  6. Include Passive Solar in Your Renovations.

    Science.gov (United States)

    Bender, Gerald F.; Probasco, Jack F.

    1981-01-01

    A checklist covers potential energy saving modifications in a building scheduled for renovation, and includes suggestions for room utilization, landscaping, and building envelope, solar control, and active system modifications. (Author)

  7. Including Indigenous Minorities in Decision-Making

    DEFF Research Database (Denmark)

    Pristed Nielsen, Helene

    Based on theories of public sphere participation and deliberative democracy, this book presents empirical results from a study of experiences with including Aboriginal and Maori groups in political decision-making in respectively Western Australia and New Zealand......Based on theories of public sphere participation and deliberative democracy, this book presents empirical results from a study of experiences with including Aboriginal and Maori groups in political decision-making in respectively Western Australia and New Zealand...

  8. Including excitons in semiconductor solar cell modelling

    OpenAIRE

    Burgelman, Marc; Minnaert, Ben

    2005-01-01

    Excitons are marginally important in classical semiconductor device physics, and their treatment is not included in standard solar cell modelling. However, in organic semiconductors and solar cells, the role of excitons is essential, as the primary effect of light absorption is exciton generation, and free electrons and holes are created by exciton dissociation. First steps to include excitons in solar cell modelling were presented by Green 1996 and Zhang 1998. Their model was restricted to a...

  9. Gas storage materials, including hydrogen storage materials

    Science.gov (United States)

    Mohtadi, Rana F; Wicks, George G; Heung, Leung K; Nakamura, Kenji

    2013-02-19

    A material for the storage and release of gases comprises a plurality of hollow elements, each hollow element comprising a porous wall enclosing an interior cavity, the interior cavity including structures of a solid-state storage material. In particular examples, the storage material is a hydrogen storage material such as a solid state hydride. An improved method for forming such materials includes the solution diffusion of a storage material solution through a porous wall of a hollow element into an interior cavity.

  10. Transmission line including support means with barriers

    Science.gov (United States)

    Cookson, Alan H.

    1982-01-01

    A gas insulated transmission line includes an elongated outer sheath, a plurality of inner conductors disposed within and extending along the outer sheath, and an insulating gas which electrically insulates the inner conductors from the outer sheath. A support insulator insulatably supports the inner conductors within the outer sheath, with the support insulator comprising a main body portion including a plurality of legs extending to the outer sheath, and barrier portions which extend between the legs. The barrier portions have openings therein adjacent the main body portion through which the inner conductors extend.

  11. Electric Power Monthly, August 1990. [Glossary included

    Energy Technology Data Exchange (ETDEWEB)

    1990-11-29

    The Electric Power Monthly (EPM) presents monthly summaries of electric utility statistics at the national, Census division, and State level. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. Data includes generation by energy source (coal, oil, gas, hydroelectric, and nuclear); generation by region; consumption of fossil fuels for power generation; sales of electric power, cost data; and unusual occurrences. A glossary is included.

  12. 42 CFR 409.10 - Included services.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Included services. 409.10 Section 409.10 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM HOSPITAL INSURANCE BENEFITS Inpatient Hospital Services and Inpatient Critical Access Hospital...

  13. Photoactive devices including porphyrinoids with coordinating additives

    Energy Technology Data Exchange (ETDEWEB)

    Forrest, Stephen R; Zimmerman, Jeramy; Yu, Eric K; Thompson, Mark E; Trinh, Cong; Whited, Matthew; Diev, Vlacheslav

    2015-05-12

    Coordinating additives are included in porphyrinoid-based materials to promote intermolecular organization and improve one or more photoelectric characteristics of the materials. The coordinating additives are selected from fullerene compounds and organic compounds having free electron pairs. Combinations of different coordinating additives can be used to tailor the characteristic properties of such porphyrinoid-based materials, including porphyrin oligomers. Bidentate ligands are one type of coordinating additive that can form coordination bonds with a central metal ion of two different porphyrinoid compounds to promote porphyrinoid alignment and/or pi-stacking. The coordinating additives can shift the absorption spectrum of a photoactive material toward higher wavelengths, increase the external quantum efficiency of the material, or both.

  14. Including knowledge creation & enabling in risk management

    OpenAIRE

    Hop, Eirik

    2015-01-01

    As a contribution to Statoil Technical Efficiency Programme (STEP), has the thesis looked at how to improve the risk management process in Statoil ASA. Through theoretical research was the primary research question created: “How can knowledge creation & enabling improve our understanding of risk management?” To create a theoretical foundation, the thesis looked at principles, methods, and models for the adequate assessment and management of risk. This includes a new perspective on ri...

  15. Rotor assembly including superconducting magnetic coil

    Science.gov (United States)

    Snitchler, Gregory L.; Gamble, Bruce B.; Voccio, John P.

    2003-01-01

    Superconducting coils and methods of manufacture include a superconductor tape wound concentrically about and disposed along an axis of the coil to define an opening having a dimension which gradually decreases, in the direction along the axis, from a first end to a second end of the coil. Each turn of the superconductor tape has a broad surface maintained substantially parallel to the axis of the coil.

  16. Including heavy flavour production in PDF fits

    OpenAIRE

    A.M. Cooper-Sarkar

    2007-01-01

    AT HERA heavy quarks may contribute up to 30% of the structure function $F_2$. The introduction of heavy quarks requires an extension of the DGLAP formalism. The effect of using different heavy flavour number schemes, and different approaches to the running of $\\alpha_s$, are compared using the ZEUS PDF fit formalism. The potential of including charm data in the fit is explored, using $D^*$ double differential cross-sections rather than the inclusive quantity $F_2^{c\\bar{c}}$.

  17. Model for safety reports including descriptive examples

    International Nuclear Information System (INIS)

    Several safety reports will be produced in the process of planning and constructing the system for disposal of high-level radioactive waste in Sweden. The present report gives a model, with detailed examples, of how these reports should be organized and what steps they should include. In the near future safety reports will deal with the encapsulation plant and the repository. Later reports will treat operation of the handling systems and the repository

  18. Electric power monthly, September 1990. [Glossary included

    Energy Technology Data Exchange (ETDEWEB)

    1990-12-17

    The purpose of this report is to provide energy decision makers with accurate and timely information that may be used in forming various perspectives on electric issues. The power plants considered include coal, petroleum, natural gas, hydroelectric, and nuclear power plants. Data are presented for power generation, fuel consumption, fuel receipts and cost, sales of electricity, and unusual occurrences at power plants. Data are compared at the national, Census division, and state levels. 4 figs., 52 tabs. (CK)

  19. The surgery of peripheral nerves (including tumors)

    DEFF Research Database (Denmark)

    Fugleholm, Kåre

    2013-01-01

    Surgical pathology of the peripheral nervous system includes traumatic injury, entrapment syndromes, and tumors. The recent significant advances in the understanding of the pathophysiology and cellular biology of peripheral nerve degeneration and regeneration has yet to be translated into improved...... nervous system response to injury are prerequisite to obtain the best possible outcome. Surgery continues to be the primary treatment modality for peripheral nerve tumors and advances in adjuvant oncological treatment has improved outcome after malignant peripheral nerve tumors. The present chapter...

  20. A kicked quantum system including the continuum

    International Nuclear Information System (INIS)

    The behaviour of a quantum particle in a separable one-term potential with three-dimensional form factor is investigated under the influence of an external force which alters the potential strength periodically or quasiperiodically. The unperturbed system possesses one bound state and a continuum of scattering states which has treated almost analytically. First numerical results, fully including the emission channel, indicate, for certain parameter combinations with commensurate or incommensurate frequency ratios, either a regular or an irregular dynamical behaviour of the system. 17 refs.; 3 figs

  1. Aerosol simulation including chemical and nuclear reactions

    Energy Technology Data Exchange (ETDEWEB)

    Marwil, E.S.; Lemmon, E.C.

    1985-01-01

    The numerical simulation of aerosol transport, including the effects of chemical and nuclear reactions presents a challenging dynamic accounting problem. Particles of different sizes agglomerate and settle out due to various mechanisms, such as diffusion, diffusiophoresis, thermophoresis, gravitational settling, turbulent acceleration, and centrifugal acceleration. Particles also change size, due to the condensation and evaporation of materials on the particle. Heterogeneous chemical reactions occur at the interface between a particle and the suspending medium, or a surface and the gas in the aerosol. Homogeneous chemical reactions occur within the aersol suspending medium, within a particle, and on a surface. These reactions may include a phase change. Nuclear reactions occur in all locations. These spontaneous transmutations from one element form to another occur at greatly varying rates and may result in phase or chemical changes which complicate the accounting process. This paper presents an approach for inclusion of these effects on the transport of aerosols. The accounting system is very complex and results in a large set of stiff ordinary differential equations (ODEs). The techniques for numerical solution of these ODEs require special attention to achieve their solution in an efficient and affordable manner. 4 refs.

  2. Blastomycosis in Northwestern Ontario, 2004 to 2014

    Directory of Open Access Journals (Sweden)

    Daniel Dalcin

    2015-01-01

    Full Text Available Blastomycosis is an invasive fungal disease caused by Blastomyces dermatitidis and the recently discovered Blastomyces gilchristii. The medical charts of 64 patients with confirmed cases of blastomycosis in northwestern Ontario during a 10-year period (2004 to 2014 were retrospectively reviewed. The number of patients diagnosed with blastomycosis in Ontario was observed to have increased substantially compared with before 1990, when blastomycosis was removed from the list of reportable diseases. Aboriginals were observed to be disproportionately represented in the patient population. Of the patients whose smoking status was known, 71.4% had a history of smoking. 59.4% of patients had underlying comorbidities and a higher comorbidity rate was observed among Aboriginal patients. The case-fatality rate from direct complications of blastomycosis disease was calculated to be 20.3%; this case-fatality rate is the highest ever to be reported in Canada and more than double that of previously published Canadian studies. The clinical characteristics of 64 patients diagnosed with blastomycosis are summarized.

  3. The endemic mimic: blastomycosis an illness often misdiagnosed.

    Science.gov (United States)

    Bradsher, Robert W

    2014-01-01

    One of the endemic fungi, Blastomyces dermatitidis, can cause epidemics of infection with multiple persons involved in a point source outbreak but more commonly causes sporadic cases of infection within the areas of endemicity. Blastomycosis can present as an acute pneumonia which is often misdiagnosed as acute pneumococcal pneumonia or the infection may present as a chronic pneumonia along with weight loss, night sweats, hemoptysis, and a lung mass suggesting tuberculosis or carcinoma of the lung. Extrapulmonary infection with B. dermatitidis is protean with many different manifestations. Most commonly, skin or subcutaneous lesions are found with either a verrucous or warty appearance or in an ulcerative form. Cases have been misidentified as keratoacanthoma, pyoderma gangrenosum, carcinoma, or as Weber-Christian panniculitis if there are nodular subcutaneous lesions. Essentially any site or organ can have lesions of disseminated blastomycosis. In our series, cases of laryngeal carcinoma, adrenal insufficiency, thyroid nodules, granulomatous hypercalcemia, abnormal mammograms thought to represent breast carcinoma, otitis media with cranial extension, immune thrombocytopenic purpura, and hemolytic anemia of unknown cause have been misdiagnosed and blastomycosis subsequently identified as the cause. This infection causes manifestations which mimic many other more commonly diagnosed conditions and must always be considered by clinicians practicing in the endemic region. PMID:25125734

  4. Investigation of anti-WI-1 adhesin antibody-mediated protection in experimental pulmonary blastomycosis.

    Science.gov (United States)

    Wüthrich, M; Klein, B S

    2000-05-01

    Infection with Blastomyces dermatitidis elicits strong antibody responses to the surface adhesin WI-1. The antibodies are directed chiefly against the adhesive domain, a 25-amino-acid repeat. Tandem-repeat-specific monoclonal antibodies (mAbs) were studied for their opsonic activity in vitro and their capacity to adoptively transfer protection in murine experimental blastomycosis. mAbs to WI-1 enhanced binding and entry of B. dermatitidis yeasts into J774. 16 cells but did not enhance killing or growth inhibition of the yeast. Passive transfer of 8 mAbs to WI-1 into 3 different inbred strains of mice also did not improve the course of experimental infection and sometimes worsened it. mu-deficient mice were more resistant to experimental blastomycosis than were intact littermates, and passive transfer of the mAbs into these mice did not protect them against experimental infection. Thus, antibody to WI-1 does not appear to improve the outcome of murine blastomycosis and may enhance the infection. PMID:10823774

  5. C-type lectin receptors differentially induce th17 cells and vaccine immunity to the endemic mycosis of North America.

    Science.gov (United States)

    Wang, Huafeng; LeBert, Vanessa; Hung, Chiung Yu; Galles, Kevin; Saijo, Shinobu; Lin, Xin; Cole, Garry T; Klein, Bruce S; Wüthrich, Marcel

    2014-02-01

    Vaccine immunity to the endemic mycoses of North America requires Th17 cells, but the pattern recognition receptors and signaling pathways that drive these protective responses have not been defined. We show that C-type lectin receptors exert divergent contributions to the development of antifungal Th17 cells and vaccine resistance against Blastomyces dermatitidis, Histoplasma capsulatum, and Coccidioides posadasii. Acquired immunity to B. dermatitidis requires Dectin-2, whereas vaccination against H. capsulatum and C. posadasii infection depends on innate sensing by Dectin-1 and Dectin-2, but not Mincle. Tracking Ag-specific T cells in vivo established that the Card9 signaling pathway acts indispensably and exclusively on differentiation of Th17 cells, while leaving intact their activation, proliferation, survival, and migration. Whereas Card9 signaling is essential, C-type lectin receptors offer distinct and divergent contributions to vaccine immunity against these endemic fungal pathogens. Our work provides new insight into innate immune mechanisms that drive vaccine immunity and Th17 cells. PMID:24391211

  6. ACCREDITATION FOR TECHNICAL ABILITIES INCLUDING COMPUTER SKILLS

    Directory of Open Access Journals (Sweden)

    Halit Hami OZ

    2013-01-01

    Full Text Available Sector Skills are defined by state-sponsored, employer-led organizations that cover specific economic sectors in the European Union and other countries in the world to reduce skills gaps and shortages, improve productivity, boost the skills of their sector workforces and improve learning supply. The accreditation and registration systems used by professional bodies raise the profile of the profession. In many countries including the European Union, professional associations are beginning to accept practice-based accreditation, generally as an alternative to their mainstream systems. Besides studying the certain agencies in the European Union for assessing/accreditating practical abilities , Accreditation for practical abilities of Information Communication Technology and Business Management/Language domains developed by Accreditation Council for Practical abilities are also studied in detail as an example to establish a similar agency in Turkey.

  7. Including electronic effects in damage cascade simulations

    International Nuclear Information System (INIS)

    A method for including the effects of electronic losses and electron-phonon coupling in radiation damage simulations has been developed and implemented for 10 keV cascades in Fe. The MD simulations are coupled to a continuum model for the electronic energy and energy lost by the atoms, due to electronic friction and electron-phonon coupling, is gained by electronic system. Electronic energy transport is described by the heat diffusion equation and energy is returned to the lattice via a stochastic force. Thus the temperature of the atomic system is controlled by a Langevin thermostat at the local electronic temperature, which varies with time and space. The results of simulations with this inhomogeneous thermostat are compared with those of homogeneous (constant temperature) thermostat simulations for a range of electron-phonon coupling strengths. The residual defect concentration was found to have a non-monotonic variation with coupling strength.

  8. Input parameters and scenarios, including economic inputs

    DEFF Research Database (Denmark)

    Boklund, Anette; Hisham Beshara Halasa, Tariq

    2012-01-01

    place, a receiving herd needed to be found. The distance, in which the receiving herd should be found, was calculated from movement data for animals and from data from trucks and abattoirs for movements to slaughter and milk tankers. For persons visiting herds, we used a combination of expert opinions......Geographical locations of the farms are the core in these models. We used geographical data, number of animals and specification of herd types for the 50,853 herds in the Danish Husbandry Register (CHR) in 2007. For each herd, the daily probability of moving animals, to another herd or to the......, disease was simulated to spread via direct contacts (movements of animals), indirect contacts (trucks and persons) and local spread (mice, birds, airborne spread in limited distances). Furthermore, in some scenarios airborne spread was included. For all contact types, when a contact was simulated to take...

  9. Critical point anomalies include expansion shock waves

    Energy Technology Data Exchange (ETDEWEB)

    Nannan, N. R., E-mail: ryan.nannan@uvs.edu [Mechanical Engineering Discipline, Anton de Kom University of Suriname, Leysweg 86, PO Box 9212, Paramaribo, Suriname and Process and Energy Department, Delft University of Technology, Leeghwaterstraat 44, 2628 CA Delft (Netherlands); Guardone, A., E-mail: alberto.guardone@polimi.it [Department of Aerospace Science and Technology, Politecnico di Milano, Via La Masa 34, 20156 Milano (Italy); Colonna, P., E-mail: p.colonna@tudelft.nl [Propulsion and Power, Delft University of Technology, Kluyverweg 1, 2629 HS Delft (Netherlands)

    2014-02-15

    From first-principle fluid dynamics, complemented by a rigorous state equation accounting for critical anomalies, we discovered that expansion shock waves may occur in the vicinity of the liquid-vapor critical point in the two-phase region. Due to universality of near-critical thermodynamics, the result is valid for any common pure fluid in which molecular interactions are only short-range, namely, for so-called 3-dimensional Ising-like systems, and under the assumption of thermodynamic equilibrium. In addition to rarefaction shock waves, diverse non-classical effects are admissible, including composite compressive shock-fan-shock waves, due to the change of sign of the fundamental derivative of gasdynamics.

  10. Critical point anomalies include expansion shock waves

    International Nuclear Information System (INIS)

    From first-principle fluid dynamics, complemented by a rigorous state equation accounting for critical anomalies, we discovered that expansion shock waves may occur in the vicinity of the liquid-vapor critical point in the two-phase region. Due to universality of near-critical thermodynamics, the result is valid for any common pure fluid in which molecular interactions are only short-range, namely, for so-called 3-dimensional Ising-like systems, and under the assumption of thermodynamic equilibrium. In addition to rarefaction shock waves, diverse non-classical effects are admissible, including composite compressive shock-fan-shock waves, due to the change of sign of the fundamental derivative of gasdynamics

  11. AMS at the ANU including biomedical applications

    Energy Technology Data Exchange (ETDEWEB)

    Fifield, L.K.; Allan, G.L.; Cresswell, R.G.; Ophel, T.R. [Australian National Univ., Canberra, ACT (Australia); King, S.J.; Day, J.P. [Manchester Univ. (United Kingdom). Dept. of Chemistry

    1993-12-31

    An extensive accelerator mass spectrometry program has been conducted on the 14UD accelerator at the Australian National University since 1986. In the two years since the previous conference, the research program has expanded significantly to include biomedical applications of {sup 26}Al and studies of landform evolution using isotopes produced in situ in surface rocks by cosmic ray bombardment. The system is now used for the measurement of {sup 10}Be, {sup 14}C, {sup 26}Al, {sup 36}Cl, {sup 59}Ni and {sup 129}I, and research is being undertaken in hydrology, environmental geochemistry, archaeology and biomedicine. On the technical side, a new test system has permitted the successful off-line development of a high-intensity ion source. A new injection line to the 14UD has been established and the new source is now in position and providing beams to the accelerator. 4 refs.

  12. CERN Technical Training: LABVIEW courses include RADE

    CERN Multimedia

    HR Department

    2009-01-01

    The contents of the "LabView Basic I" and "LabView Intermediate II" courses have recently been changed to include, respectively, an introduction to and expert training in the Rapid Application Development Environment (RADE). RADE is a LabView-based application developed at CERN to integrate LabView in the accelerator and experiment control infrastructure. It is a suitable solution to developing expert tools, machine development analysis and independent test facilities. The course names have also been changed to "LabVIEW Basics I with RADE Introduction" and "LabVIEW Intermediate II with Advanced RADE Application". " LabVIEW Basics I with RADE Introduction" is designed for: Users preparing to develop applications using LabVIEW, or NI Developer Suite; users and technical managers evaluating LabVIEW or NI Developer Suite in purchasing decisions; users pursuing the Certified LabVIEW Developer certification. The course prepares participants to develop test and measurement, da...

  13. CERN Technical Training: LABVIEW courses include RADE

    CERN Multimedia

    HR Department

    2009-01-01

    The contents of the "LabView Basic I" and "LabView Intermediate II" courses have recently been changed to include, respectively, an introduction to and expert training in the Rapid Application Development Environment (RADE). RADE is a LabView-based application developed at CERN to integrate LabView in the accelerator and experiment control infrastructure. It is a suitable solution to developing expert tools, machine development analysis and independent test facilities. The course names have also been changed to "LabVIEW Basics I with RADE Introduction" and "LabVIEW Intermediate II with Advanced RADE Application". " LabVIEW Basics I with RADE Introduction" is designed for: Users preparing to develop applications using LabVIEW, or NI Developer Suite; users and technical managers evaluating LabVIEW or NI Developer Suite in purchasing decisions; users pursuing the Certified LabVIEW Developer certification. The course pr...

  14. CLIC expands to include the Southern Hemisphere

    CERN Multimedia

    Roberto Cantoni

    2010-01-01

    Australia has recently joined the CLIC collaboration: the enlargement will bring new expertise and resources to the project, and is especially welcome in the wake of CERN budget redistributions following the recent adoption of the Medium Term Plan.   The countries involved in CLIC collaboration With the signing of a Memorandum of Understanding on 26 August 2010, the ACAS network (Australian Collaboration for Accelerator Science) became the 40th member of in the multilateral CLIC collaboration making Australia the 22nd country to join the collaboration. “The new MoU was signed by the ACAS network, which includes the Australian Synchrotron and the University of Melbourne”, explains Jean-Pierre Delahaye, CLIC Study Leader. “Thanks to their expertise, the Australian institutes will contribute greatly to the CLIC damping rings and the two-beam test modules." Institutes from any country wishing to join the CLIC collaboration are invited to assume responsibility o...

  15. CERN Technical Training: LABVIEW courses include RADE

    CERN Multimedia

    HR Department

    2009-01-01

    The contents of "LabView Basic I" and "LabView Intermediate II" trainings have been recently changed to include, respectively, an introduction and an expert training on the Rapid Application Development Environment (RADE). RADE is a LabView-based application developed at CERN to integrate LabView in the accelerator and experiment control infrastructure. It is a suitable solution to develop expert tools, machine development analysis and independent test facilities. The course names have also been changed to "LabVIEW Basics I with RADE Introduction" and "LabVIEW Intermediate II with Advanced RADE Application". " LabVIEW Basics I with RADE Introduction" is designed for: Users preparing to develop applications using LabVIEW, or NI Developer Suite; users and technical managers evaluating LabVIEW or NI Developer Suite in purchasing decisions; users pursuing the Certified LabVIEW Developer certification. The course prepare...

  16. Extending Newtonian Dynamics to Include Stochastic Processes

    Science.gov (United States)

    Zak, Michail

    2009-01-01

    A paper presents further results of continuing research reported in several previous NASA Tech Briefs articles, the two most recent being Stochastic Representations of Chaos Using Terminal Attractors (NPO-41519), [Vol. 30, No. 5 (May 2006), page 57] and Physical Principle for Generation of Randomness (NPO-43822) [Vol. 33, No. 5 (May 2009), page 56]. This research focuses upon a mathematical formalism for describing post-instability motions of a dynamical system characterized by exponential divergences of trajectories leading to chaos (including turbulence as a form of chaos). The formalism involves fictitious control forces that couple the equations of motion of the system with a Liouville equation that describes the evolution of the probability density of errors in initial conditions. These stabilizing forces create a powerful terminal attractor in probability space that corresponds to occurrence of a target trajectory with probability one. The effect in configuration space (ordinary three-dimensional space as commonly perceived) is to suppress exponential divergences of neighboring trajectories without affecting the target trajectory. As a result, the post-instability motion is represented by a set of functions describing the evolution of such statistical quantities as expectations and higher moments, and this representation is stable.

  17. Alternating phase focussing including space charge

    International Nuclear Information System (INIS)

    Longitudinal stability can be obtained in a non-relativistic drift tube accelerator by traversing each gap as the rf accelerating field rises. However, the rising accelerating field leads to a transverse defocusing force which is usually overcome by magnetic focussing inside the drift tubes. The radio frequency quadrupole is one way of providing simultaneous longitudinal and transverse focusing without the use of magnets. One can also avoid the use of magnets by traversing alternate gaps between drift tubes as the field is rising and falling, thus providing an alternation of focussing and defocusing forces in both the longitudinal and transverse directions. The stable longitudinal phase space area is quite small, but recent efforts suggest that alternating phase focussing (APF) may permit low velocity acceleration of currents in the 100-300 ma range. This paper presents a study of the parameter space and a test of crude analytic predictions by adapting the code PARMILA, which includes space charge, to APF. 6 refs., 3 figs

  18. Langevin simulations of QCD, including fermions

    International Nuclear Information System (INIS)

    We encounter critical slow down in updating when xi/a -> infinite and in matrix inversion (needed to include fermions) when msub(q)a -> 0. A simulation that purports to solve QCD numerically will encounter these limits, so to face the challenge in the title of this workshop, we must cure the disease of critical slow down. Physically, this critical slow down is due to the reluctance of changes at short distances to propagate to large distances. Numerically, the stability of an algorithm at short wavelengths requires a (moderately) small step size; critical slow down occurs when the effective long wavelength step size becomes tiny. The remedy for this disease is an algorithm that propagates signals quickly throughout the system; i.e. one whose effective step size is not reduced for the long wavelength conponents of the fields. (Here the effective ''step size'' is essentially an inverse decorrelation time.) To do so one must resolve various wavelengths of the system and modify the dynamics (in CPU time) of the simulation so that all modes evolve at roughly the same rate. This can be achieved by introducing Fourier transforms. I show how to implement Fourier acceleration for Langevin updating and for conjugate gradient matrix inversion. The crucial feature of these algorithms that lends them to Fourier acceleration is that they update the lattice globally; hence the Fourier transforms are computed once per sweep rather than once per hit. (orig./HSI)

  19. SEEPAGE MODEL FOR PA INCLUDING DRIFT COLLAPSE

    Energy Technology Data Exchange (ETDEWEB)

    C. Tsang

    2004-09-22

    The purpose of this report is to document the predictions and analyses performed using the seepage model for performance assessment (SMPA) for both the Topopah Spring middle nonlithophysal (Tptpmn) and lower lithophysal (Tptpll) lithostratigraphic units at Yucca Mountain, Nevada. Look-up tables of seepage flow rates into a drift (and their uncertainty) are generated by performing numerical simulations with the seepage model for many combinations of the three most important seepage-relevant parameters: the fracture permeability, the capillary-strength parameter 1/a, and the percolation flux. The percolation flux values chosen take into account flow focusing effects, which are evaluated based on a flow-focusing model. Moreover, multiple realizations of the underlying stochastic permeability field are conducted. Selected sensitivity studies are performed, including the effects of an alternative drift geometry representing a partially collapsed drift from an independent drift-degradation analysis (BSC 2004 [DIRS 166107]). The intended purpose of the seepage model is to provide results of drift-scale seepage rates under a series of parameters and scenarios in support of the Total System Performance Assessment for License Application (TSPA-LA). The SMPA is intended for the evaluation of drift-scale seepage rates under the full range of parameter values for three parameters found to be key (fracture permeability, the van Genuchten 1/a parameter, and percolation flux) and drift degradation shape scenarios in support of the TSPA-LA during the period of compliance for postclosure performance [Technical Work Plan for: Performance Assessment Unsaturated Zone (BSC 2002 [DIRS 160819], Section I-4-2-1)]. The flow-focusing model in the Topopah Spring welded (TSw) unit is intended to provide an estimate of flow focusing factors (FFFs) that (1) bridge the gap between the mountain-scale and drift-scale models, and (2) account for variability in local percolation flux due to

  20. Including lifestyle medicine in undergraduate medical curricula

    Directory of Open Access Journals (Sweden)

    Edward Phillips

    2015-02-01

    Full Text Available Purpose: Currently, there is no model to integrate the discipline of lifestyle medicine (LM into undergraduate medical education. Furthermore, there are no guidelines, validated assessment tools, or evaluation or implementation plans in place. Background: The World Health Organization predicts that by 2020, two-thirds of disease worldwide will be the result of poor lifestyle choices. Fewer than 50% of US primary care physicians routinely provide specific guidance on nutrition, physical activity, or weight control. Methods: We are establishing a plan to integrate LM into medical school education in collaboration with the investing stakeholders, including medical school deans and students, medical curriculum developers and researchers, medical societies, governing bodies, and policy institutes. Three planning and strategy meetings are being held to address key areas of focus – with a particular interest in nutrition, physical activity, student self-care, and behavior change – to develop specific implementation guidelines and landmarks. Results: After the first two meetings, the proposed areas of focus were determined to be: 1 supporting of deans and key personnel, 2 creation of federal and state policy commitments, 3 use of assessment as a driver of LM, 4 provision of high-quality evidence-based curricular material on an easily navigated site, and 5 engaging student interest. Implementation strategies for each focus area will be addressed in an upcoming planning meeting in early 2015. Conclusion: This initiative is expected to have important public health implications by efficiently promoting the prevention and treatment of non-communicable chronic disease with a scalable and sustainable model to educate physicians in training and practice.

  1. Compact Radar Transceiver with Included Calibration

    Science.gov (United States)

    McLinden, Matthew; Rincon, Rafael

    2013-01-01

    The Digital Beamforming Synthetic Aperture Radar (DBSAR) is an eight-channel phased array radar system that employs solid-state radar transceivers, a microstrip patch antenna, and a reconfigurable waveform generator and processor unit. The original DBSAR transceiver design utilizes connectorized electronic components that tend to be physically large and heavy. To achieve increased functionality in a smaller volume, PCB (printed circuit board) transceivers were designed to replace the large connectorized transceivers. One of the most challenging problems designing the transceivers in a PCB format was achieving proper performance in the calibration path. For a radar loop-back calibration path, a portion of the transmit signal is coupled out of the antenna feed and fed back into the receiver. This is achieved using passive components for stability and repeatability. Some signal also leaks through the receive path. As these two signal paths are correlated via an unpredictable phase, the leakage through the receive path during transmit must be 30 dB below the calibration path. For DBSAR s design, this requirement called for a 100-dB isolation in the receiver path during transmit. A total of 16 solid-state L-band transceivers on a PCB format were designed. The transceivers include frequency conversion stages, T/R switching, and a calibration path capable of measuring the transmit power-receiver gain product during transmit for pulse-by-pulse calibration or matched filtering. In particular, this calibration path achieves 100-dB isolation between the transmitted signal and the low-noise amplifier through the use of a switching network and a section of physical walls achieving attenuation of radiated leakage. The transceivers were designed in microstrip PCBs with lumped elements and individually packaged components for compactness. Each transceiver was designed on a single PCB with a custom enclosure providing interior walls and compartments to isolate transceiver

  2. Ocean storage, including costs and risks

    International Nuclear Information System (INIS)

    The long-term effectiveness of ocean storage will have to be based on theoretical understanding and models as there is no way to perform experiments on the required time and space scales for outgassing estimation. Based on observations of tracer behavior, the ventilation time of deep water has been revealed. Calibrated and constrained by these results, most of the OGCMs tell us that CO2 injected into the thermohaline circulation would not come back to the atmosphere in more than several hundred years. There are two types of concepts of ocean storage: one is a lake type concept to keep the CO2 at the ocean floor or a depression site as long as possible, and the other is to inject CO2 into the deep waters so that it is dispersed as quickly as possible. The technological concepts so far for implementation with minimum environmental impacts are much elaborated based on laboratory and computer experiments incorporating the key understanding of the CO2 clathrate properties attained in this decade. The frequently addressed concern of this technology includes the ecological modification of the ocean system. But even in the business-as-usual release of CO2 into the atmosphere, some modification might be foreseen in the deep ocean environment and could be inevitable not caused by the climate change but by the direct influence of the increase in the CO2 concentration in deep waters in future. We cannot stop the CO2 invasion into the deep ocean due to the existing of the excess CO2 in the atmosphere. Whichever release method is used, carbon dioxide we are releasing to the atmosphere now will find its way into the deep oceans. Hence, the right scientific question is whether there exist additional risks to the deep sea environment associated with this technology. If we accept the target of a stabilization level of the atmospheric concentration of CO2, our generation's commitment to the CO2 futures anyway extends to the modification of the deep sea environment induced by the

  3. An Integrated Biochemistry Laboratory, Including Molecular Modeling

    Science.gov (United States)

    Hall, Adele J. Wolfson Mona L.; Branham, Thomas R.

    1996-11-01

    The dilemma of designing an advanced undergraduate laboratory lies in the desire to teach and reinforce basic principles and techniques while at the same time exposing students to the excitement of research. We report here on a one-semester, project-based biochemistry laboratory that combines the best features of a cookbook approach (high success rate, achievement of defined goals) with those of an investigative, discovery-based approach (student involvement in the experimental design, excitement of real research). Individual modules may be selected and combined to meet the needs of different courses and different institutions. The central theme of this lab is protein purification and design. This laboratory accompanies the first semester of biochemistry (Structure and Function of Macromolecules, a course taken mainly by junior and senior chemistry and biological chemistry majors). The protein chosen as the object of study is the enzyme lysozyme, which is utilized in all projects. It is suitable for a student lab because it is easily and inexpensively obtained from egg white and is extremely stable, and its high isoelectric point (pI = 11) allows for efficient separation from other proteins by ion-exchange chromatography. Furthermore, a literature search conducted by the resourceful student reveals a wealth of information, since lysozyme has been the subject of numerous studies. It was the first enzyme whose structure was determined by crystallography (1). Hendrickson et al. (2) have previously described an intensive one-month laboratory course centered around lysozyme, although their emphasis is on protein stability rather than purification and engineering. Lysozyme continues to be the focus of much exciting new work on protein folding and dynamics, structure and activity (3 - 5). This lab course includes the following features: (i) reinforcement of basic techniques, such as preparation of buffers, simple enzyme kinetics, and absorption spectroscopy; (ii

  4. Ionic liquids, electrolyte solutions including the ionic liquids, and energy storage devices including the ionic liquids

    Energy Technology Data Exchange (ETDEWEB)

    Gering, Kevin L.; Harrup, Mason K.; Rollins, Harry W.

    2015-12-08

    An ionic liquid including a phosphazene compound that has a plurality of phosphorus-nitrogen units and at least one pendant group bonded to each phosphorus atom of the plurality of phosphorus-nitrogen units. One pendant group of the at least one pendant group comprises a positively charged pendant group. Additional embodiments of ionic liquids are disclosed, as are electrolyte solutions and energy storage devices including the embodiments of the ionic liquid.

  5. Comparative genomics allowed the identification of drug targets against human fungal pathogens

    Directory of Open Access Journals (Sweden)

    Martins Natalia F

    2011-01-01

    Full Text Available Abstract Background The prevalence of invasive fungal infections (IFIs has increased steadily worldwide in the last few decades. Particularly, there has been a global rise in the number of infections among immunosuppressed people. These patients present severe clinical forms of the infections, which are commonly fatal, and they are more susceptible to opportunistic fungal infections than non-immunocompromised people. IFIs have historically been associated with high morbidity and mortality, partly because of the limitations of available antifungal therapies, including side effects, toxicities, drug interactions and antifungal resistance. Thus, the search for alternative therapies and/or the development of more specific drugs is a challenge that needs to be met. Genomics has created new ways of examining genes, which open new strategies for drug development and control of human diseases. Results In silico analyses and manual mining selected initially 57 potential drug targets, based on 55 genes experimentally confirmed as essential for Candida albicans or Aspergillus fumigatus and other 2 genes (kre2 and erg6 relevant for fungal survival within the host. Orthologs for those 57 potential targets were also identified in eight human fungal pathogens (C. albicans, A. fumigatus, Blastomyces dermatitidis, Paracoccidioides brasiliensis, Paracoccidioides lutzii, Coccidioides immitis, Cryptococcus neoformans and Histoplasma capsulatum. Of those, 10 genes were present in all pathogenic fungi analyzed and absent in the human genome. We focused on four candidates: trr1 that encodes for thioredoxin reductase, rim8 that encodes for a protein involved in the proteolytic activation of a transcriptional factor in response to alkaline pH, kre2 that encodes for α-1,2-mannosyltransferase and erg6 that encodes for Δ(24-sterol C-methyltransferase. Conclusions Our data show that the comparative genomics analysis of eight fungal pathogens enabled the identification of

  6. Correspondence between future-included and future-not-included theories

    CERN Document Server

    Nagao, Keiichi

    2013-01-01

    We briefly review the correspondence principle proposed in our previous paper, which claims that if we regard a matrix element defined in terms of the future state at time $T_B$ and the past state at time $T_A$ as an expectation value in the complex action theory whose path runs over not only past but also future, the expectation value at the present time $t$ of a future-included theory for large $T_B-t$ and large $t-T_A$ corresponds to that of a future-not-included theory with a proper inner product for large $t-T_A$. This correspondence principle suggests that the future-included theory is not excluded phenomenologically.

  7. Launch Lock Assemblies Including Axial Gap Amplification Devices and Spacecraft Isolation Systems Including the Same

    Science.gov (United States)

    Barber, Tim Daniel (Inventor); Hindle, Timothy (Inventor); Young, Ken (Inventor); Davis, Torey (Inventor)

    2014-01-01

    Embodiments of a launch lock assembly are provided, as are embodiments of a spacecraft isolation system including one or more launch lock assemblies. In one embodiment, the launch lock assembly includes first and second mount pieces, a releasable clamp device, and an axial gap amplification device. The releasable clamp device normally maintains the first and second mount pieces in clamped engagement; and, when actuated, releases the first and second mount pieces from clamped engagement to allow relative axial motion there between. The axial gap amplification device normally residing in a blocking position wherein the gap amplification device obstructs relative axial motion between the first and second mount pieces. The axial gap amplification device moves into a non-blocking position when the first and second mount pieces are released from clamped engagement to increase the range of axial motion between the first and second mount pieces.

  8. Synthese von Melanin und Pityriacitrin bei Exophiala dermatitidis : ein Vergleich zweier UV-protektiver Substanzen

    OpenAIRE

    Juncu, Christian Gheorghe

    2007-01-01

    Durch Zugabe von Tryptophan als alleiniger Stickstoffquelle zu einem Minimalagar konnten Mayser et al. den Hefepilz M. furfur zur Bildung von Pigmenten und Fluorochromen anregen. Es wurde eine neuartige chemische Verbindung isoliert und erstmalig beschrieben, welche einen komplexen UV-Filter darstellt. Das Indolderivat mit der Summenformel C20H13N30 wurde Pityriacitrin genannt (Mayser et al. 1998; Mayser et al. 2002). Nachdem phylogenetisch weit entfernte Pilze ebenfalls zur Pigmentprodukti...

  9. Faults of Europe including Turkey (flt4_2l)

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This coverage includes arcs that describe faults found in the surface outcrops of bedrock of Europe including Turkey (Albania, Andorra, Austria, Belgium, Bosnia and...

  10. Should Relational Aggression Be Included in DSM-V?

    Science.gov (United States)

    Keenan, Kate; Coyne, Claire; Lahey, Benjamin B.

    2008-01-01

    The study examines whether relational aggression should be included in DSM-V disruptive behavior disorders. The results conclude that some additional information is gathered from assessing relational aggression but not enough to be included in DSM-V.

  11. Partially ionized plasmas including the third symposium on uranium plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Krishnan, M. [ed.

    1976-09-01

    Separate abstracts are included for 28 papers on electrically generated plasmas, fission generated plasmas, nuclear pumped lasers, gaseous fuel reactor research, and applications. Five papers have been previously abstracted and included in ERA.

  12. 20 CFR 220.114 - Evaluation of symptoms, including pain.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Evaluation of symptoms, including pain. 220... RETIREMENT ACT DETERMINING DISABILITY Medical Considerations § 220.114 Evaluation of symptoms, including pain...'s symptoms, including pain, and the extent to which the claimant's symptoms can reasonably...

  13. Microfluidic devices and methods including porous polymer monoliths

    Energy Technology Data Exchange (ETDEWEB)

    Hatch, Anson V.; Sommer, Gregory j.; Singh, Anup K.; Wang, Ying-Chih; Abhyankar, Vinay

    2015-12-01

    Microfluidic devices and methods including porous polymer monoliths are described. Polymerization techniques may be used to generate porous polymer monoliths having pores defined by a liquid component of a fluid mixture. The fluid mixture may contain iniferters and the resulting porous polymer monolith may include surfaces terminated with iniferter species. Capture molecules may then be grafted to the monolith pores.

  14. Solar Energy Education. Reader, Part II. Sun story. [Includes glossary

    Energy Technology Data Exchange (ETDEWEB)

    1981-05-01

    Magazine articles which focus on the subject of solar energy are presented. The booklet prepared is the second of a four part series of the Solar Energy Reader. Excerpts from the magazines include the history of solar energy, mythology and tales, and selected poetry on the sun. A glossary of energy related terms is included. (BCS)

  15. 7 CFR 1437.303 - Aquaculture, including ornamental fish.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Aquaculture, including ornamental fish. 1437.303... ASSISTANCE PROGRAM Determining Coverage Using Value § 1437.303 Aquaculture, including ornamental fish. (a... humans; and (3) Ornamental fish propagated and reared in an aquatic medium. (b) The aquacultural...

  16. Including Siblings in the Treatment of Child Sexual Abuse.

    Science.gov (United States)

    Baker, Juanita N.; Tanis, Heyley J.; Rice, Jennifer B.

    2001-01-01

    Describes the necessity of including siblings in the treatment of victims of child sexual abuse. Theoretical and practical reasons to include siblings in treatment are discussed. Case examples using a particular intervention approach and results of client satisfaction surveys are described. (Contains 18 references.) (GCP)

  17. 20 CFR 404.1312 - World War II service included.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false World War II service included. 404.1312... DISABILITY INSURANCE (1950- ) Wage Credits for Veterans and Members of the Uniformed Services World War II Veterans § 404.1312 World War II service included. Your service was in the active service of the...

  18. 31 CFR 103.51 - Dollars as including foreign currency.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Dollars as including foreign currency... RECORDKEEPING AND REPORTING OF CURRENCY AND FOREIGN TRANSACTIONS General Provisions § 103.51 Dollars as including foreign currency. Wherever in this part an amount is stated in dollars, it shall be deemed to...

  19. 26 CFR 1.1013-1 - Property included in inventory.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Property included in inventory. 1.1013-1 Section... inventory. The basis of property required to be included in inventory is the last inventory value of such property in the hands of the taxpayer. The requirements with respect to the valuation of an inventory...

  20. Microfluidic devices and methods including porous polymer monoliths

    Science.gov (United States)

    Hatch, Anson V; Sommer, Gregory J; Singh, Anup K; Wang, Ying-Chih; Abhyankar, Vinay V

    2014-04-22

    Microfluidic devices and methods including porous polymer monoliths are described. Polymerization techniques may be used to generate porous polymer monoliths having pores defined by a liquid component of a fluid mixture. The fluid mixture may contain iniferters and the resulting porous polymer monolith may include surfaces terminated with iniferter species. Capture molecules may then be grafted to the monolith pores.

  1. Making Way and Making Sense: Including Newcomers in Interaction

    Science.gov (United States)

    Pillet-Shore, Danielle

    2010-01-01

    In our everyday interactions as they unfold in real time, how do we do including? This article examines a specific set of interactional moments when the potential to be included (or not) recurs: when a newcomer arrives to some social scene where two or more already-present persons are actively engaged in some activity and that newcomer displays…

  2. Articles which include chevron film cooling holes, and related processes

    Energy Technology Data Exchange (ETDEWEB)

    Bunker, Ronald Scott; Lacy, Benjamin Paul

    2014-12-09

    An article is described, including an inner surface which can be exposed to a first fluid; an inlet; and an outer surface spaced from the inner surface, which can be exposed to a hotter second fluid. The article further includes at least one row or other pattern of passage holes. Each passage hole includes an inlet bore extending through the substrate from the inlet at the inner surface to a passage hole-exit proximate to the outer surface, with the inlet bore terminating in a chevron outlet adjacent the hole-exit. The chevron outlet includes a pair of wing troughs having a common surface region between them. The common surface region includes a valley which is adjacent the hole-exit; and a plateau adjacent the valley. The article can be an airfoil. Related methods for preparing the passage holes are also described.

  3. Stages of Plasma Cell Neoplasms (Including Multiple Myeloma)

    Science.gov (United States)

    ... Treatment Health Professional Plasma Cell Neoplasms Treatment Research Plasma Cell Neoplasms (Including Multiple Myeloma) Treatment (PDQ®)–Patient Version General Information About Plasma Cell Neoplasms Go to Health Professional Version Key ...

  4. Treatment Options for Plasma Cell Neoplasms (Including Multiple Myeloma)

    Science.gov (United States)

    ... Treatment Health Professional Plasma Cell Neoplasms Treatment Research Plasma Cell Neoplasms (Including Multiple Myeloma) Treatment (PDQ®)–Patient Version General Information About Plasma Cell Neoplasms Go to Health Professional Version Key ...

  5. Chronic Obstructive Pulmonary Disease (COPD) Includes: Chronic Bronchitis and Emphysema

    Science.gov (United States)

    ... Obstructive Pulmonary Disease (COPD) Includes: Chronic Bronchitis and Emphysema Recommend on Facebook Tweet Share Compartir Data are ... of adults who have ever been diagnosed with emphysema: 3.4 million Percent of adults who have ...

  6. Pets: Your Plan Should Include All Family Members

    Science.gov (United States)

    ... Emergencies › Pets Pets Your Plan Should Include All Family Members The best way to protect your household ... About Us Latest News Search for Jobs Military Families Disaster Relief International Services National Celebrity Cabinet Mission & ...

  7. Prototype solar heating and cooling systems, including potable hot water

    Science.gov (United States)

    Bloomquist, D.; Oonk, R. L.

    1977-01-01

    Progress made in the development, delivery, and support of two prototype solar heating and cooling systems including potable hot water is reported. The system consists of the following subsystems: collector, auxiliary heating, potable hot water, storage, control, transport, and government-furnished site data acquisition. A comparison of the proposed Solaron Heat Pump and Solar Desiccant Heating and Cooling Systems, installation drawings, data on the Akron House at Akron, Ohio, and other program activities are included.

  8. Including patients’ perspectives in patient information leaflets: A polyocular approach

    DEFF Research Database (Denmark)

    Fage-Butler, Antoinette Mary

    2013-01-01

    asymmetries. The paper contributes theoretically in its innovative use of perspectivist theory in relation to text, and in identifying that the insights of polyocularity could valuably inform a new health communication paradigm, as current health communication paradigms do not fully recognize patients......Existing research reveals that patients’ perspectives are missing from mandatory patient information leaflets (PILs). At the same time, there is overwhelming consensus that they should be included in this genre, and a corresponding need for potential approaches to tackle this problem. This paper......’ perspectives. Apart from its theoretical contributions, the paper includes guidelines to support the production of PILs where patients’ perspectives are included. The guidelines are informed by practices that have characterised previous polyocular communication events, as well as research into how to maximize...

  9. Multidisciplinary treatment for advanced and recurrent breast cancer including brachytherapy

    Energy Technology Data Exchange (ETDEWEB)

    Tsukiyama, Iwao; Ohno, Tatsuya (Tochigi Cancer Center, Utsunomiya (Japan). Hospital); Takizawa, Yoshikazu; Ikeda, Hiroshi; Egawa, Sunao; Ogino, Takashi

    1994-06-01

    Between 1986 and 1992, 10 patients (12 lesions) of advanced breast cancer were treated with multidisciplinary treatment including brachytherapy. The lesions treated included 5 primary breast tumors, 3 metastatic lesions in the contra lateral breast, 2 recurrences after external beam irradiation, 1 metastasis to the axillary lymph node and 1 metastasis to the upper arm skin. The interstitial irradiation techniques used were [sup 192]Ir low dose-rate irradiation for 5 lesions and high dose-rate for 7 lesions (including 3 with mould irradiation). External hyperthermia as performed for 6 lesions and interstitial hyperthermia were performed for 4 lesions. The local response was CR for 3 lesions, PRa for 8 lesions, PRb for 1 lesion with the local response rate being 100%. Excellent local control could be achieved by combination external and interstitial irradiation, indicating that radiotherapy is definitely useful for the treatment of advanced breast cancer. (author).

  10. Pediatric deformity treatment update, including 3D correction concepts%Pediatric deformity treatment update,including 3D correction concepts

    Institute of Scientific and Technical Information of China (English)

    Randal R. Betz; Patrick J. Cahill; Joshua M. Pahys; Amer F. Samdani

    2011-01-01

    The purpose of this article is to highlight some of the new developments in the treatment of adolescent idiopathic scoliosis,including 3D correction of deformity,posterior and minimally invasive surgery,and fusionless strategies.

  11. Tunable cavity resonator including a plurality of MEMS beams

    Energy Technology Data Exchange (ETDEWEB)

    Peroulis, Dimitrios; Fruehling, Adam; Small, Joshua Azariah; Liu, Xiaoguang; Irshad, Wasim; Arif, Muhammad Shoaib

    2015-10-20

    A tunable cavity resonator includes a substrate, a cap structure, and a tuning assembly. The cap structure extends from the substrate, and at least one of the substrate and the cap structure defines a resonator cavity. The tuning assembly is positioned at least partially within the resonator cavity. The tuning assembly includes a plurality of fixed-fixed MEMS beams configured for controllable movement relative to the substrate between an activated position and a deactivated position in order to tune a resonant frequency of the tunable cavity resonator.

  12. Solar Energy Education. Renewable energy: a background text. [Includes glossary

    Energy Technology Data Exchange (ETDEWEB)

    1985-01-01

    Some of the most common forms of renewable energy are presented in this textbook for students. The topics include solar energy, wind power hydroelectric power, biomass ocean thermal energy, and tidal and geothermal energy. The main emphasis of the text is on the sun and the solar energy that it yields. Discussions on the sun's composition and the relationship between the earth, sun and atmosphere are provided. Insolation, active and passive solar systems, and solar collectors are the subtopics included under solar energy. (BCS)

  13. EC6 safety enhancement - including impact of Fukushima lessons learned

    International Nuclear Information System (INIS)

    The Enhanced CANDU® 6 (EC6) is the new Generation III CANDU reactor design that meets the most up to date regulatory requirements and customer expectations. EC6 builds on the proven high performance design such as the Qinshan CANDU 6 units and has made improvements to safety and operational performance, and has incorporated extensive operational feedback including Fukushima. The Fukushima Dai-ichi March 11, 2011 event has demonstrated the importance of defence-in-depth considerations for beyond-design basis events, including severe accidents. The EC6 design is based on the defence-in-depth principles and provides further design features that address the lessons learned from Fukushima. (author)

  14. Theory of nanorod antenna resonances including end-reflection phase

    Science.gov (United States)

    Su, Wei; Li, Xiangyin; Bornemann, Jens; Gordon, Reuven

    2015-04-01

    We present a fully analytic theory for nanorod resonances including the phase of reflection from the rounded ends using a transmission line approach. It combines the circuit theory response of spherical nanoparticles with standard transmission line theory using the Sommerfeld wave dispersion. The approach agrees well with comprehensive numerical calculations.

  15. Everglades National Park Including Biscayne National Park. Activity Book.

    Science.gov (United States)

    Ruehrwein, Dick

    Intended to help elementary school children learn about the resources of the Everglades and Biscayne National Parks, this activity book includes information, puzzles, games, and quizzes. The booklet deals with concepts related to: (1) the seasons; (2) fire ecology; (3) water; (4) fish; (5) mammals; (6) mosquitos; (7) birds; (8) venomous snakes;…

  16. A Reactive Behavior Agent: Including Emotions into a Video Game

    Directory of Open Access Journals (Sweden)

    A. L. Laureano-Cruces

    2012-10-01

    Full Text Available Why we have emotions and how they influence human behavior are two questions we constantly ask ourselves.According to researchers in the field, there are two kinds of information that the person receives to make a decision.This information is integrated to generate a whole. One comes from ourselves it is proprioceptive and refers toemotions; the other one is external, it comes from the environment. Thus, emotions are immersed in different areas ofa person’s life, including social, functional, and cognitive aspects. It has an important role in the decision-makingprocess. It is on this last point that this paper focuses its approach, which consists of including a cognitive structure ofemotions in a reactive behavior in order to enrich behavior, including the information generated through internalevaluation of the external physical stimuli. Our work is based on the OCC theory (named after the name of its authors:Ortony, Collins and Clore. This theory proposes that a decision-making process is affected through differentperspectives: a goals and events, b agents and their actions, and c objects and their capacity for attraction. Thecase study is situated within a scenario that represents an approach that seeks to include a module of emotions withinthe design of the architecture of a videogame.

  17. Assessing the Doctoral Thesis When It Includes Published Work

    Science.gov (United States)

    Sharmini, Sharon; Spronken-Smith, Rachel; Golding, Clinton; Harland, Tony

    2015-01-01

    In this article we explore how examiners assess a thesis that includes published work. An online survey was used to gather data on approaches to assessing publication-based theses (PBTs). The respondents were 62 supervisors who had experience examining PBTs across a range of disciplines at a research-intensive university in New Zealand. Nearly…

  18. Including Religion in American History: Some Notes on Student Resistance.

    Science.gov (United States)

    Talbert, Kevin M.; Romanowski, Michael H.

    2002-01-01

    Focuses on the importance of teaching religion in U.S. history courses. Discusses problems that teachers encounter when teaching religion, addresses the issue of students resisting learning about religion in the history classroom, and explores how teachers can reduce this resistance. Includes references. (CMK)

  19. Mixture including hydrogen and hydrocarbon having pressure-temperature stability

    Science.gov (United States)

    Mao, Wendy L. (Inventor); Mao, Ho-Kwang (Inventor)

    2009-01-01

    The invention relates to a method of storing hydrogen that employs a mixture of hydrogen and a hydrocarbon that can both be used as fuel. In one embodiment, the method involves maintaining a mixture including hydrogen and a hydrocarbon in the solid state at ambient pressure and a temperature in excess of about 10 K.

  20. Computer aided design of reentrant coaxial filters including coaxial excitation

    NARCIS (Netherlands)

    Boria, V.; Gerini, G.; Guglielmi, M.

    1999-01-01

    An advanced EM based CAD tool is used for the detailed characterisation of a family of reentrant coaxial waveguide filters. The EM analysis includes the effects of tuning screws and of the input/output coaxial excitation. The software is essentially used as an efficient replacement for the tradition

  1. Interviewing Objects: Including Educational Technologies as Qualitative Research Participants

    Science.gov (United States)

    Adams, Catherine A.; Thompson, Terrie Lynn

    2011-01-01

    This article argues the importance of including significant technologies-in-use as key qualitative research participants when studying today's digitally enhanced learning environments. We gather a set of eight heuristics to assist qualitative researchers in "interviewing" technologies-in-use (or other relevant objects), drawing on concrete…

  2. LTRACK: Beam-transport calculation including wakefield effects

    International Nuclear Information System (INIS)

    LTRACK is a first-order beam-transport code that includes wakefield effects up to quadrupole modes. This paper will introduce the readers to this computer code by describing the history, the method of calculations, and a brief summary of the input/output information. Future plans for the code will also be described

  3. Including Parents in School Governance: Rhetoric or Reality

    Science.gov (United States)

    Ng, Shun Wing

    2013-01-01

    Purpose: The purpose of this paper is to report a qualitative study exploring how parents have been included in school governance in Hong Kong and in what ways their roles have been evolving in state education. Design/methodology/approach: The qualitative method was adopted in this exploratory study, the findings of which help provide insights for…

  4. Prototype solar heating and cooling systems including potable hot water

    Science.gov (United States)

    1978-01-01

    Progress is reviewed in the development, delivery, and support of two prototype solar heating and cooling systems including potable hot water. The system consisted of the following subsystems: collector, auxiliary heating, potable hot water, storage, control, transport, and government-furnished site data acquisition.

  5. Including Non-Traditional Instrumentation in Undergraduate Environmental Chemistry Courses

    Science.gov (United States)

    Jenkins, J. David; Orvis, Jessica N.; Smith, C. Jimmy; Manley, Citabria; Rice, Jeanette K. 2

    2004-01-01

    Non-traditional instrumentation was obtained for Georgia Southern undergraduates to attain fundamental environmental education through unique laboratory experiences. In this context, the method for including a direct mercury analyzer into both major and non-major environmental laboratories is reported.

  6. Payment Services for Global Online Systems Including Internet.

    Science.gov (United States)

    Seebeck, Bill; And Others

    1995-01-01

    A panel of four conference presenters address issues related to paying for services provided through online systems. Discussion includes the following topics: metering devices; electronic/digital cash; working within existing banking/credit card structures; provision of payment mechanisms in countries without extensive credit card usage; and…

  7. Testing Intelligently Includes Double-Checking Wechsler IQ Scores

    Science.gov (United States)

    Kuentzel, Jeffrey G.; Hetterscheidt, Lesley A.; Barnett, Douglas

    2011-01-01

    The rigors of standardized testing make for numerous opportunities for examiner error, including simple computational mistakes in scoring. Although experts recommend that test scoring be double-checked, the extent to which independent double-checking would reduce scoring errors is not known. A double-checking procedure was established at a…

  8. Novel model for wine fermentation including the yeast dying phase

    OpenAIRE

    Borzì, Alfio; Merger, Juri; Müller, Jonas; Rosch, Achim; Schenk, Christina; Schmidt, Dominik; Schmidt, Stephan; Schulz, Volker; Velten, Kai; von Wallbrunn, Christian; Zänglein, Michael

    2014-01-01

    This paper presents a novel model for wine fermentation including a death phase for yeast and the influence of oxygen on the process. A model for the inclusion of the yeast dying phase is derived and compared to a model taken from the literature. The modeling ability of the several models is analyzed by comparing their simulation results.

  9. Including investment risk in large-scale power market models

    DEFF Research Database (Denmark)

    Lemming, Jørgen Kjærgaard; Meibom, P.

    2003-01-01

    Long-term energy market models can be used to examine investments in production technologies, however, with market liberalisation it is crucial that such models include investment risks and investor behaviour. This paper analyses how the effect of investment risk on production technology selection...... can be included in large-scale partial equilibrium models of the power market. The analyses are divided into a part about risk measures appropriate for power market investors and a more technical part about the combination of a risk-adjustment model and a partial-equilibrium model. To illustrate the...... analyses quantitatively, a framework based on an iterative interaction between the equilibrium model and a separate risk-adjustment module was constructed. To illustrate the features of the proposed modelling approach we examined how uncertainty in demand and variable costs affects the optimal choice of...

  10. XFEL OSCILLATOR SIMULATION INCLUDING ANGLE-DEPENDENT CRYSTAL REFLECTIVITY

    International Nuclear Information System (INIS)

    The oscillator package within the GINGER FEL simulation code has now been extended to include angle-dependent reflectivity properties of Bragg crystals. Previously, the package was modified to include frequencydependent reflectivity in order to model x-ray FEL oscillators from start-up from shot noise through to saturation. We present a summary of the algorithms used for modeling the crystal reflectivity and radiation propagation outside the undulator, discussing various numerical issues relevant to the domain of high Fresnel number and efficient Hankel transforms. We give some sample XFEL-O simulation results obtained with the angle-dependent reflectivity model, with particular attention directed to the longitudinal and transverse coherence of the radiation output.

  11. Tissue-Specific Effects of Bariatric Surgery Including Mitochondrial Function

    Directory of Open Access Journals (Sweden)

    Simon N. Dankel

    2011-01-01

    Full Text Available A better understanding of the molecular links between obesity and disease is potentially of great benefit for society. In this paper we discuss proposed mechanisms whereby bariatric surgery improves metabolic health, including acute effects on glucose metabolism and long-term effects on metabolic tissues (adipose tissue, skeletal muscle, and liver and mitochondrial function. More short-term randomized controlled trials should be performed that include simultaneous measurement of metabolic parameters in different tissues, such as tissue gene expression, protein profile, and lipid content. By directly comparing different surgical procedures using a wider array of metabolic parameters, one may further unravel the mechanisms of aberrant metabolic regulation in obesity and related disorders.

  12. Improving the strength of amalgams by including steel fibers

    International Nuclear Information System (INIS)

    Highlights: ► A room temperature liquid Ga–In alloy was successfully substituted for mercury. ► Physically sound amalgams with included steel fibers can be made. ► A small volume fraction inclusion of fibers increased strength by ∼20%. - Abstract: Mercury amalgams, due to their material properties, are widely and successfully used in dental practice. They are, however, also well recognized as having poor tensile strength. With the possibility of expanding amalgam applications it is demonstrated that tensile strength can be increased some 20% by including a small amount of steel fibers. Furthermore, it is shown that mercury can be replaced with a room temperature liquid gallium–indium alloy. Processing, microstructures, and mechanical test results of these novel amalgams are presented and discussed in view of means to further improve their properties.

  13. Improving the strength of amalgams by including steel fibers

    Energy Technology Data Exchange (ETDEWEB)

    Cochran, Calvin T. [Hendrix College, Conway, AR 72032 (United States); Van Hoose, James R. [Siemens, Orlando, FL 32826 (United States); McGill, Preston B. [Marshall Space Flight Center, EM20, Huntsville, AL 35812 (United States); Grugel, Richard N., E-mail: richard.n.grugel@nasa.gov [Marshall Space Flight Center, EM30, Huntsville, AL 35812 (United States)

    2012-05-30

    Highlights: Black-Right-Pointing-Pointer A room temperature liquid Ga-In alloy was successfully substituted for mercury. Black-Right-Pointing-Pointer Physically sound amalgams with included steel fibers can be made. Black-Right-Pointing-Pointer A small volume fraction inclusion of fibers increased strength by {approx}20%. - Abstract: Mercury amalgams, due to their material properties, are widely and successfully used in dental practice. They are, however, also well recognized as having poor tensile strength. With the possibility of expanding amalgam applications it is demonstrated that tensile strength can be increased some 20% by including a small amount of steel fibers. Furthermore, it is shown that mercury can be replaced with a room temperature liquid gallium-indium alloy. Processing, microstructures, and mechanical test results of these novel amalgams are presented and discussed in view of means to further improve their properties.

  14. The bispectrum of cosmic string temperature fluctuations including recombination effects

    CERN Document Server

    Regan, Donough

    2015-01-01

    We calculate the cosmic microwave background temperature bispectrum from cosmic strings, for the first time including the contributions from the last scattering surface, using a well-established Gaussian model for the string energy-momentum correlation functions, and a simplified model for the cosmic fluid. We check our approximation for the integrated Sachs-Wolfe (ISW) contribution against the bispectrum obtained from the full sky map of the cosmic string ISW signal used by the Planck team, obtaining good agreement. We validate our model for the last scattering surface contribution by comparing the predicted temperature power spectrum with that obtained from a full Boltzmann code treatment applied to the Unconnected Segment Model of a string network. We find that including the last scattering contribution has only a small impact on the upper limit on the string tension resulting from the bispectrum at Planck resolutions, and argue that the bispectrum is unlikely to be competitive with the power spectrum at a...

  15. Topology of dynamical lattice configurations including results from overlap fermions

    CERN Document Server

    Bruckmann, Falk; Gruber, Florian; Lippert, Thomas; Schäfer, Andreas

    2011-01-01

    We investigate how the topological charge density in lattice QCD simulations is affected by violations of chiral symmetry caused by the fermion action. To this end we compare lattice configurations generated with a number of different actions including first configurations generated with exact overlap quarks. We visualize the topological profiles after mild smearing. In the topological charge correlator we measure the size of the positive core, which is known to vanish in the continuum limit. To leading order we find the core size to scale linearly with the lattice spacing with the same coefficient for all actions, even including quenched simulations. In the subleading term the different actions vary over a range of about 10%. Our findings suggest that non-chiral lattice actions at current lattice spacings do not differ much for observables related to topology, both among themselves and compared to overlap fermions.

  16. Management of radioactive waste from reprocessing including disposal aspects

    International Nuclear Information System (INIS)

    Based on a hypothetical scenario including a reactor park of 20 GWe consisting of Pressurised-Water-Reactors with a resulting annual production of 600 tonnes of heavy metal of spent fuel, all aspects of management of resulting wastes are studied. Waste streams from reprocessing include gaseous and liquid effluents, and a number of solid conditioned waste types. Disposal of waste is supposed to be performed either in a near-surface engineered repository, as long as the content of alpha-emitting radionuclides is low enough, and in a deep geological granite formation. After having estimated quantities, cost and radiological consequences, the sensitivity of results to modification in reactor park size, burn-up and the introduction of mixed-oxide fuel (MOX) is evaluated

  17. The Physics of Semiconductors An Introduction Including Devices and Nanophysics

    CERN Document Server

    Grundmann, Marius

    2006-01-01

    The Physics of Semiconductors provides material for a comprehensive upper-level-undergrauate and graduate course on the subject, guiding readers to the point where they can choose a special topic and begin supervised research. The textbook provides a balance between essential aspects of solid-state and semiconductor physics, on the one hand, and the principles of various semiconductor devices and their applications in electronic and photonic devices, on the other. It highlights many practical aspects of semiconductors such as alloys, strain, heterostructures, nanostructures, that are necessary in modern semiconductor research but typically omitted in textbooks. For the interested reader some additional advanced topics are included, such as Bragg mirrors, resonators, polarized and magnetic semiconductors are included. Also supplied are explicit formulas for many results, to support better understanding. The Physics of Semiconductors requires little or no prior knowledge of solid-state physics and evolved from ...

  18. Survey of state legislative programs that include passive solar energy

    Energy Technology Data Exchange (ETDEWEB)

    Weiss, S

    1979-06-01

    This report surveys and evaluates state-level solar-incentive programs, including passive solar energy. The range of programs examined focuses on financial and legal incentives designed to speed the implementation of solar heating, cooling, and hot water systems. They have been evaluated by probing the wording of the incentive legislation and by interviewing state program administrators in each state to determine: (1) the extent, if any, of passive inclusion in solar-incentive programs, and (2) the level of success that various implementation techniques have achieved for encouraging passive solar designs as opposed to the more-commonly-understood active systems. Because no states have initiated incentive legislation designed exclusively to encourage passive solar techniques, it has been essential to determine whether legislative programs explicitly or implicitly include passive solar or if they explicitly exclude it.

  19. Microfluidic System Simulation Including the Electro-Viscous Effect

    Science.gov (United States)

    Rojas, Eileen; Chen, C. P.; Majumdar, Alok

    2007-01-01

    This paper describes a practical approach using a general purpose lumped-parameter computer program, GFSSP (Generalized Fluid System Simulation Program) for calculating flow distribution in a network of micro-channels including electro-viscous effects due to the existence of electrical double layer (EDL). In this study, an empirical formulation for calculating an effective viscosity of ionic solutions based on dimensional analysis is described to account for surface charge and bulk fluid conductivity, which give rise to electro-viscous effect in microfluidics network. Two dimensional slit micro flow data was used to determine the model coefficients. Geometry effect is then included through a Poiseuille number correlation in GFSSP. The bi-power model was used to calculate flow distribution of isotropically etched straight channel and T-junction microflows involving ionic solutions. Performance of the proposed model is assessed against experimental test data.

  20. Optimization of pipe networks including pumps by simulated annealing

    OpenAIRE

    Costa A.L.H.; Medeiros J.L.; Pessoa F.L.P.

    2000-01-01

    The objective of this work is to present an application of the simulated annealing method for the optimal design of pipe networks including pumps. Although its importance, the optimization of pumped networks did not receive great attention in the literature. The proposed search scheme explores the discrete space of the decision variables: pipe diameters and pump sizes. The behavior of the pumps is describe through the characteristic curve, generating more realistic solutions. In order to demo...

  1. Mix design of bituminous materials including reclaimed asphalt pavement

    OpenAIRE

    Dubois, Vincent; De La Roche, Chantal

    2008-01-01

    Reclaimed asphalt, obtained by milling of asphalt road layers can be re-used at once or stored. In the case of storage, an heterogeneity issue may occur when several types of materials, with different origins are mixed. At the scale of a storage zone or a stock pile, composition and properties of the reclaimed asphalts will be different, including variations of the final material properties, constraints for the stock manager, and the necessary adaptation of the manufacturing process. The recl...

  2. DILIGENT - Preliminary training plan (includes training support environment) - M9

    OpenAIRE

    Castelli, Donatella; Manieri, Andrea; Stein, Adeheit; Niederee, Claudia; Schek, Hans-J?rg; Schuldt, Heiko

    2005-01-01

    This report presents the plans for the DILIGENT intra-project, inter-project and external training activities. It describes the initial strategic and operational plans for each of these types of training (D4.1.2). The report includes a textual description of the training support environment (D4.1.1). For the intra-project training which started at Month 6, it also reports some of the already completed activities.

  3. Stochastic modelling of two-phase flows including phase change

    International Nuclear Information System (INIS)

    Stochastic modelling has already been developed and applied for single-phase flows and incompressible two-phase flows. In this article, we propose an extension of this modelling approach to two-phase flows including phase change (e.g. for steam-water flows). Two aspects are emphasised: a stochastic model accounting for phase transition and a modelling constraint which arises from volume conservation. To illustrate the whole approach, some remarks are eventually proposed for two-fluid models. (authors)

  4. Include medical ethics in the Research Excellence Framework

    OpenAIRE

    Kong, W.M.; Vernon, B.; Boyd, K; Gillon, R; Farsides, B; Stirrat, G

    2011-01-01

    The Research Excellence Framework of the Higher Education Funding Council for England is taking place in 2013, its three key elements being outputs (65% of the profile), impact (20%), and “quality of the research environment” (15%). Impact will be assessed using case studies that “may include any social, economic or cultural impact or benefit beyond academia that has taken place during the assessment period.”1 Medical ethics in the UK still does not have its own cognate ...

  5. Compendium of practices for including children in family sessions

    OpenAIRE

    Carr, Alan.

    2002-01-01

    The approach to involving children in family counselling described here is based on three principles. First, at an ethical level children have a right to participate in the process of solving problems of living which they and their families face. Second, at a pragmatic level counselling has a better chance of success if those involved in the problem, including children, participate in the solution. Third, at a theoretical level, methods of engaging children in counselling must be based on an ...

  6. Budgetary Effects of Including the CEC into Dynamic Modulation

    OpenAIRE

    Banse, Martin; Grethe, Harald

    2002-01-01

    The EU Commission suggests to exclude CEC from the dynamic modulation mechanism, being part of the MTR package. This article looks at the distributional aspects of including the CEC into dynamic modulation. Under the current accession proposal the CEC would account for only 18% of the rural development budget by 2006. If modulation would be realised with the CEC being excluded this share would drop to 14% by 2010. According to the criteria proposed by the Commission for the distribution of th...

  7. Should LSP Dictionaries. also Include Professional Jargon and Slang?

    OpenAIRE

    Rosemarie Gläser

    2011-01-01

    Abstract: The paper discusses the question whether an LSP dictionary should take the sociolinguistic stratification of the entire speech community in a particular domain of activity into consideration, and as a consequence, also encompass vocabulary on the lower stylistic levels, such as professional jargon and occupational slang in addition to technical terminology and nomenclature. The author's contention is that by including such vocabulary, an LSP dictionary will be more comprehe...

  8. Production, control and utilization of radioisotopes including radiopharmaceuticals

    International Nuclear Information System (INIS)

    From April 29th to May 5th, 1984 27 participants from 21 developing countries stayed within an IAEA Study Tour ('Production, Control and Utilization of Radioisotopes including Radiopharmaceuticals') in the GDR. In the CINR, Rossendorf the reactor, the cyclotron, the technological centre as well as the animal test laboratory were visited. The participants were made familiar by 10 papers with the development, production and control of radiopharmaceuticals in the CINR, Rossendorf. (author)

  9. Towards a general framework for including noise impacts in LCA

    OpenAIRE

    Cucurachi, Stefano; Heijungs, Reinout; Ohlau, Katrin

    2012-01-01

    Purpose Several damages have been associated with the exposure of human beings to noise. These include auditory effects, i.e., hearing impairment, but also non-auditory physiological ones such as hypertension and ischemic heart disease, or psychological ones such as annoyance, depression, sleep disturbance, limited performance of cognitive tasks or inadequate cognitive development. Noise can also interfere with intended activities, both in daytime and nighttime. ISO 14'040 also indicated the ...

  10. THE EFFECTS OF INCLUDING BANKRUPTCY ON DYNAMIC INVESTMENT DECISIONS

    OpenAIRE

    Frank S. Novak; Schnitkey, Gary D.

    1994-01-01

    This article evaluates the effects of including the costs of bankruptcy in a dynamic model of off-farm investment decisions using a stochastic dynamic programming (SDP) model which incorporates the stochastic dynamic nature of investment returns and the interrelationships between financial structure and investment decisions. Our results suggest that in the presence of bankruptcy, optimal investment decisions are affected by financial structure and financial market conditions. Ignoring bankrup...

  11. Search for BSM physics including dark matter at ATLAS

    CERN Document Server

    Ju, Xiangyang; The ATLAS collaboration

    2016-01-01

    The increased centre-of-mass energy of the proton-proton collisions of the LHC run 2 gives a unique opportunity to extend the sensitivity to the production of particles not foreseen by the Standard Model. This talk summarises recent ATLAS results on BSM searches. Although the focus is on searches for production of DM particles, results include searches for heavy resonances in many final states and for production of supersymmetric particles.

  12. New chemical evolution analytical solutions including environment effects

    CERN Document Server

    Spitoni, E

    2015-01-01

    In the last years, more and more interest has been devoted to analytical solutions, including inflow and outflow, to study the metallicity enrichment in galaxies. In this framework, we assume a star formation rate which follows a linear Schmidt law, and we present new analytical solutions for the evolution of the metallicity (Z) in galaxies. In particular, we take into account environmental effects including primordial and enriched gas infall, outflow, different star formation efficiencies, and galactic fountains. The enriched infall is included to take into account galaxy-galaxy interactions. Our main results can be summarized as: i) when a linear Schmidt law of star formation is assumed, the resulting time evolution of the metallicity Z is the same either for a closed-box model or for an outflow model. ii) The mass-metallicity relation for galaxies which suffer a chemically enriched infall, originating from another evolved galaxy with no pre-enriched gas, is shifted down in parallel at lower Z values, if co...

  13. Modeling heart rate variability including the effect of sleep stages

    Science.gov (United States)

    Soliński, Mateusz; Gierałtowski, Jan; Żebrowski, Jan

    2016-02-01

    We propose a model for heart rate variability (HRV) of a healthy individual during sleep with the assumption that the heart rate variability is predominantly a random process. Autonomic nervous system activity has different properties during different sleep stages, and this affects many physiological systems including the cardiovascular system. Different properties of HRV can be observed during each particular sleep stage. We believe that taking into account the sleep architecture is crucial for modeling the human nighttime HRV. The stochastic model of HRV introduced by Kantelhardt et al. was used as the initial starting point. We studied the statistical properties of sleep in healthy adults, analyzing 30 polysomnographic recordings, which provided realistic information about sleep architecture. Next, we generated synthetic hypnograms and included them in the modeling of nighttime RR interval series. The results of standard HRV linear analysis and of nonlinear analysis (Shannon entropy, Poincaré plots, and multiscale multifractal analysis) show that—in comparison with real data—the HRV signals obtained from our model have very similar properties, in particular including the multifractal characteristics at different time scales. The model described in this paper is discussed in the context of normal sleep. However, its construction is such that it should allow to model heart rate variability in sleep disorders. This possibility is briefly discussed.

  14. Transport Phenomena in Thin Rotating Liquid Films Including: Nucleate Boiling

    Science.gov (United States)

    Faghri, Amir

    2005-01-01

    In this grant, experimental, numerical and analytical studies of heat transfer in a thin liquid film flowing over a rotating disk have been conducted. Heat transfer coefficients were measured experimentally in a rotating disk heat transfer apparatus where the disk was heated from below with electrical resistance heaters. The heat transfer measurements were supplemented by experimental characterization of the liquid film thickness using a novel laser based technique. The heat transfer measurements show that the disk rotation plays an important role on enhancement of heat transfer primarily through the thinning of the liquid film. Experiments covered both momentum and rotation dominated regimes of the flow and heat transfer in this apparatus. Heat transfer measurements have been extended to include evaporation and nucleate boiling and these experiments are continuing in our laboratory. Empirical correlations have also been developed to provide useful information for design of compact high efficiency heat transfer devices. The experimental work has been supplemented by numerical and analytical analyses of the same problem. Both numerical and analytical results have been found to agree reasonably well with the experimental results on liquid film thickness and heat transfer Coefficients/Nusselt numbers. The numerical simulations include the free surface liquid film flow and heat transfer under disk rotation including the conjugate effects. The analytical analysis utilizes an integral boundary layer approach from which

  15. Multi-processor including data flow accelerator module

    Science.gov (United States)

    Davidson, George S.; Pierce, Paul E.

    1990-01-01

    An accelerator module for a data flow computer includes an intelligent memory. The module is added to a multiprocessor arrangement and uses a shared tagged memory architecture in the data flow computer. The intelligent memory module assigns locations for holding data values in correspondence with arcs leading to a node in a data dependency graph. Each primitive computation is associated with a corresponding memory cell, including a number of slots for operands needed to execute a primitive computation, a primitive identifying pointer, and linking slots for distributing the result of the cell computation to other cells requiring that result as an operand. Circuitry is provided for utilizing tag bits to determine automatically when all operands required by a processor are available and for scheduling the primitive for execution in a queue. Each memory cell of the module may be associated with any of the primitives, and the particular primitive to be executed by the processor associated with the cell is identified by providing an index, such as the cell number for the primitive, to the primitive lookup table of starting addresses. The module thus serves to perform functions previously performed by a number of sections of data flow architectures and coexists with conventional shared memory therein. A multiprocessing system including the module operates in a hybrid mode, wherein the same processing modules are used to perform some processing in a sequential mode, under immediate control of an operating system, while performing other processing in a data flow mode.

  16. The COG database: an updated version includes eukaryotes

    Directory of Open Access Journals (Sweden)

    Sverdlov Alexander V

    2003-09-01

    Full Text Available Abstract Background The availability of multiple, essentially complete genome sequences of prokaryotes and eukaryotes spurred both the demand and the opportunity for the construction of an evolutionary classification of genes from these genomes. Such a classification system based on orthologous relationships between genes appears to be a natural framework for comparative genomics and should facilitate both functional annotation of genomes and large-scale evolutionary studies. Results We describe here a major update of the previously developed system for delineation of Clusters of Orthologous Groups of proteins (COGs from the sequenced genomes of prokaryotes and unicellular eukaryotes and the construction of clusters of predicted orthologs for 7 eukaryotic genomes, which we named KOGs after eukaryotic orthologous groups. The COG collection currently consists of 138,458 proteins, which form 4873 COGs and comprise 75% of the 185,505 (predicted proteins encoded in 66 genomes of unicellular organisms. The eukaryotic orthologous groups (KOGs include proteins from 7 eukaryotic genomes: three animals (the nematode Caenorhabditis elegans, the fruit fly Drosophila melanogaster and Homo sapiens, one plant, Arabidopsis thaliana, two fungi (Saccharomyces cerevisiae and Schizosaccharomyces pombe, and the intracellular microsporidian parasite Encephalitozoon cuniculi. The current KOG set consists of 4852 clusters of orthologs, which include 59,838 proteins, or ~54% of the analyzed eukaryotic 110,655 gene products. Compared to the coverage of the prokaryotic genomes with COGs, a considerably smaller fraction of eukaryotic genes could be included into the KOGs; addition of new eukaryotic genomes is expected to result in substantial increase in the coverage of eukaryotic genomes with KOGs. Examination of the phyletic patterns of KOGs reveals a conserved core represented in all analyzed species and consisting of ~20% of the KOG set. This conserved portion of the

  17. 77 FR 9969 - Clow Water Systems Company Including On-Site Leased Workers From Carol Harris Stafffing Including...

    Science.gov (United States)

    2012-02-21

    ... on December 29, 2011(76 FR 81988). At the request of the State agency, the Department reviewed the... Employment and Training Administration Clow Water Systems Company Including On-Site Leased Workers From Carol... leased workers from Carol Harris Staffing, Coshocton, Ohio. The workers are engaged in activities...

  18. Developing HYDMN code to include the transient of MNSR

    International Nuclear Information System (INIS)

    A description of the programs added to HYDMN code (a code for thermal-hydraulic steady state of MNSR) to include the transient of the same MNSR is presented. The code asks the initial conditions for the power (in k W) and the cold initial core inlet temperature (in degrees centigrade). A time-dependent study of the coolant inlet and outlet temperature, its speed, pool and tank temperatures is done for MNSR in general and for the Syrian MNSR in particular. The study solves the differential equations taken from reference (1) by using some numerical methods found in reference (3). The code becomes this way independent of any external information source. (Author)

  19. The action principle for generalized fluid motion including gyroviscosity

    CERN Document Server

    Lingam, M

    2014-01-01

    A general set of fluid equations that allow for energy-conserving momentum transport by gyroscopic motion of fluid elements is obtained. The equations are produced by a class of action principles that yield a large subset of the known fluid and magnetofluid models, including gyroviscosity. Analysis of the action principle yields broad, model-independent results regarding the conservation laws of energy and linear and angular momenta. The formalism is illustrated by studying fluid models with intrinsic angular momentum that may appear in the contexts of condensed matter, biological, and other areas of physics.

  20. The action principle for generalized fluid motion including gyroviscosity

    Science.gov (United States)

    Lingam, M.; Morrison, P. J.

    2014-11-01

    A general set of fluid equations that allow for energy-conserving momentum transport by gyroscopic motion of fluid elements is obtained. The equations are produced by a class of action principles that yield a large subset of the known fluid and magnetofluid models, including gyroviscosity. Analysis of the action principle yields broad, model-independent results regarding the conservation laws of energy and linear and angular momenta. The formalism is illustrated by studying fluid models with intrinsic angular momentum that may appear in the contexts of condensed matter, biological, and other areas of physics.

  1. Composite material including nanocrystals and methods of making

    Science.gov (United States)

    Bawendi, Moungi G.; Sundar, Vikram C.

    2010-04-06

    Temperature-sensing compositions can include an inorganic material, such as a semiconductor nanocrystal. The nanocrystal can be a dependable and accurate indicator of temperature. The intensity of emission of the nanocrystal varies with temperature and can be highly sensitive to surface temperature. The nanocrystals can be processed with a binder to form a matrix, which can be varied by altering the chemical nature of the surface of the nanocrystal. A nanocrystal with a compatibilizing outer layer can be incorporated into a coating formulation and retain its temperature sensitive emissive properties.

  2. Collective Atomic Recoil Lasing Including Friction and Diffusion Effects

    CERN Document Server

    Robb, G R M; Ferraro, A; Bonifacio, R; Courteille, P W; Zimmermann, C; Courteille, Ph.W.

    2003-01-01

    We extend the Collective Atomic Recoil Lasing (CARL) model including the effects of friction and diffusion forces acting on the atoms due to the presence of optical molasses fields. The results from this model are consistent with those from a recent experiment by Kruse et al. [Phys. Rev. Lett. 91, 183601 (2003)]. In particular, we obtain a threshold condition above which collective backscattering occurs. Using a nonlinear analysis we show that the backscattered field and the bunching evolve to a steady-state, in contrast to the non-stationary behaviour of the standard CARL model. For a proper choice of the parameters, this steady-state can be superfluorescent.

  3. Composite armor, armor system and vehicle including armor system

    Science.gov (United States)

    Chu, Henry S.; Jones, Warren F.; Lacy, Jeffrey M.; Thinnes, Gary L.

    2013-01-01

    Composite armor panels are disclosed. Each panel comprises a plurality of functional layers comprising at least an outermost layer, an intermediate layer and a base layer. An armor system incorporating armor panels is also disclosed. Armor panels are mounted on carriages movably secured to adjacent rails of a rail system. Each panel may be moved on its associated rail and into partially overlapping relationship with another panel on an adjacent rail for protection against incoming ordnance from various directions. The rail system may be configured as at least a part of a ring, and be disposed about a hatch on a vehicle. Vehicles including an armor system are also disclosed.

  4. Quasilocal density functional theory for nuclei including pairing correlations

    International Nuclear Information System (INIS)

    We propose first a generalization of the Density Functional Theory leading to single-particle equations of motion with a quasilocal mean-field operator containing a position-dependent effective mass and a spin-orbit potential. Ground-state properties of doubly magic nuclei are obtained within this framework using the Gogny D1S force and compared with the exact Hartree-Fock values. Next, extend the Density Functional Theory to include pairing correlations without formal violation of the particle-number condition. This theory, which is nonlocal, is simplified by a suitable quasilocal reduction. Some calculations to show the ability of this theory are presented. (author)

  5. Constraints on Dark Energy Models Including Gamma Ray Bursts

    OpenAIRE

    Li, Hong; SU, MENG; Fan, Zuhui; Dai, Zigao; Zhang, Xinmin

    2006-01-01

    In this paper we analyze the constraints on the property of dark energy from cosmological observations. Together with SNe Ia Gold sample, WMAP, SDSS and 2dFGRS data, we include 69 long Gamma-Ray Bursts (GRBs) data in our study and perform global fitting using Markov Chain Monte Carlo (MCMC) technique. Dark energy perturbations are explicitly considered. We pay particular attention to the time evolution of the equation of state of dark energy parameterized as $w_{DE}=w_0+w_a(1-a)$ with $a$ the...

  6. How to include farmers in the emission trading system?

    DEFF Research Database (Denmark)

    Svendsen, Gert Tinggaard

    2011-01-01

    The EU has committed itself to an ambitious 20 % reduction of greenhouse gases (GHG) by 2020 compared to the 1990 emissions level. Moreover, the EU goal beyond 2012 is to strengthen, expand and improve climate change initiatives. Therefore, there is a strong need to consider more carefully how to...... integrate as many sectors as possible in these efforts. Farmers, however, do not trade GHG under the Kyoto agreement. The idea of including farmers in a national emission trading system has been launched in Australia but it has not yet been applied to the EU....

  7. Extended 1D Method for Coherent Synchrotron Radiation including Shielding

    CERN Document Server

    Sagan, David; Mayes, Christopher; Sae-Ueng, Udom

    2008-01-01

    Coherent Synchrotron Radiation can severely limit the performance of accelerators designed for high brightness and short bunch length. Examples include light sources based on ERLs or FELs, and bunch compressors for linear colliders. In order to better simulate Coherent Synchrotron Radiation, the established 1-dimensional formalism is extended to work at lower energies, at shorter bunch lengths, and for an arbitrary configuration of multiple bends. Wide vacuum chambers are simulated by means of vertical image charges. This formalism has been implemented in the general beam dynamics code "Bmad" and its results are here compared to analytical approximations, to numerical solutions of the Maxwell equations, and to the simulation code "elegant".

  8. Visió general de la discussió sobre les àrees d’exclusió del projecte INCLUD-ED General overview of the discussion on exclusion areas in the INCLUD-ED project Visión general de la discusión sobre las áreas de exclusión del proyecto INCLUD-ED

    OpenAIRE

    Carme García; Itxaso Tellado; Tiziana Chiappelli

    2010-01-01

    En aquest article es discuteixen les aportacions que es fan des del projecte INCLUD-ED: Strategies for inclusion and social cohesion from education in Europe sobre la relació que es pot establir entre l’exclusió/inclusió educativa i l’exclusió/inclusió en quatre àrees de la societat: ocupació, habitatge, salut i participació social i política. En particular, es reflexiona sobre els efectes que té tant l’exclusió, com formes de superar-la i promoure la inclusió, en les situacions que han d’afr...

  9. Thyroid cancer development in Chernobyl including new additional results

    International Nuclear Information System (INIS)

    Full text: We have been studying the etiology of thyroid cancer development among the exposed people in Hiroshima. In 1993, we have proposed the hypothesis of oncology model of thyroid cancer development in children following the nuclear power plant accident in Chernobyl, and then related studies has been done in Chernobyl and also in Hiroshima. Following findings are included. Urinary iodine level was lower in Chernobyl than in Hiroshima. Stimulation of ret oncogene in thyroid cancer tissues, and appearance of nuclear abnormalities of thyroid follicular cells were found higher rate among the exposed people. Sensitivity of TSH-receptor in thyroid tissues (TSH-R mRNA expression) was higher while young. Synergistic effect of TSH-R mRNA and ER mRNA expressions were found in both of normal tissues and cancer tissues in thyroid, but it was more apparent in cancer tissues. These findings gave the additional proofs on the hypothesis of thyroid cancer development in Chernobyl. Including these results, we like to present the importance of thyroid for the health of the exposed people in Chernobyl

  10. Chronic lymphocytic leukemia: a clinical review including Korean cohorts

    Science.gov (United States)

    Jeon, Young-Woo; Cho, Seok-Goo

    2016-01-01

    Only 5th decade ago, chronic lymphocytic leukemia (CLL) was only recognized as disease group of presenting features like peripheral lymphocytosis, organomegaly including of splenomegaly. As understanding of disease biology and molecular diagnostic tools are getting improved gradually, characterization of variation in CLL’s clinical courses was facilitated, resulting in better risk stratification and targeted treatments. Consequently multiple new targeted agents have been used in treatment of CLL, it makes improved clinical outcome. Rituximab containing chemoimmunotherapy (combination of rituximab, fludarabine, and cyclophosphamide) have shown better overall response rate and progression-free survival on fit patients’ group in front-line setting, result in standard first-line therapeutic option for CLL. Furthermore, after introducing that the B-cell receptor is crucial for the evolution and progression of CLL, emerging treatments targeting highly activated surface antigens and oncogenic signaling pathways have been associated with several successes in recent decades. These include new anti-CD 20 monoclonal antibody (obinutuzumab), the bruton tyrosine kinase inhibitor (ibrutinib), the phosphatidylinositol 3-kinase inhibitor (idelalisib), and B-cell CLL/lymphoma 2 inhibitor (ABT-199 and ABT-263). So, we discuss not only general pathophysiology of CLL, but also rapidly advancing treatment strategies that are being studied or approved for treatment of CLL. PMID:27044858

  11. Chemical Compatibility Testing Final Report Including Test Plans and Procedures

    International Nuclear Information System (INIS)

    This report provides an independent assessment of information on mixed waste streams, chemical compatibility information on polymers, and standard test methods for polymer properties. It includes a technology review of mixed low-level waste (LLW) streams and material compatibilities, validation for the plan to test the compatibility of simulated mixed wastes with potential seal and liner materials, and the test plan itself. Potential packaging materials were reviewed and evaluated for compatibility with expected hazardous wastes. The chemical and physical property measurements required for testing container materials were determined. Test methodologies for evaluating compatibility were collected and reviewed for applicability. A test plan to meet US Department of Energy and Environmental Protection Agency requirements was developed. The expected wastes were compared with the chemical resistances of polymers, the top-ranking polymers were selected for testing, and the most applicable test methods for candidate seal and liner materials were determined. Five recommended solutions to simulate mixed LLW streams are described. The test plan includes descriptions of test materials, test procedures, data collection protocols, safety and environmental considerations, and quality assurance procedures. The recommended order of testing to be conducted is specified

  12. Community Assessment Tool for Public Health Emergencies Including Pandemic Influenza

    Energy Technology Data Exchange (ETDEWEB)

    ORAU' s Oak Ridge Institute for Science Education (HCTT-CHE)

    2011-04-14

    The Community Assessment Tool (CAT) for Public Health Emergencies Including Pandemic Influenza (hereafter referred to as the CAT) was developed as a result of feedback received from several communities. These communities participated in workshops focused on influenza pandemic planning and response. The 2008 through 2011 workshops were sponsored by the Centers for Disease Control and Prevention (CDC). Feedback during those workshops indicated the need for a tool that a community can use to assess its readiness for a disaster - readiness from a total healthcare perspective, not just hospitals, but the whole healthcare system. The CAT intends to do just that - help strengthen existing preparedness plans by allowing the healthcare system and other agencies to work together during an influenza pandemic. It helps reveal each core agency partners (sectors) capabilities and resources, and highlights cases of the same vendors being used for resource supplies (e.g., personal protective equipment [PPE] and oxygen) by the partners (e.g., public health departments, clinics, or hospitals). The CAT also addresses gaps in the community's capabilities or potential shortages in resources. This tool has been reviewed by a variety of key subject matter experts from federal, state, and local agencies and organizations. It also has been piloted with various communities that consist of different population sizes, to include large urban to small rural communities.

  13. Control rod calibration including the rod coupling effect

    International Nuclear Information System (INIS)

    In a reactor containing more than one control rod, which includes all reactors licensed in the United States, there will be a 'coupling' or 'shadowing' of control rod flux at the location of a control rod as a result of the flux depression caused by another control rod. It was decided to investigate this phenomenon further, and eventually to put calibration table data or formulae in a small computer in the control room, so once could insert the positions of the three control rods and receive the excess reactivity without referring to separate tables. For this to be accomplished, a 'three control- rod reactivity function' would be used which would include the flux coupling between the rods. The function is design and measured data was fitted into it to determine the calibration constants. The input data for fitting the trial functions consisted of 254 data points, each consisting of the position of the reg, shim, and transient rods, and the total excess reactivity. (About 200 of these points were 'critical balance points', that is the rod positions for which reactor was critical, and the remainder were determined by positive period measurements.) Although this may be unrealistic from a physical viewpoint, the function derived gave a very accurate recalculation of the input data, and thus would faithfully give the excess reactivity for any possible combination of the locations of the three control rods. The next step, incorporation of the three-rod function into the minicomputer, will be pursued in the summer and fall of 1984

  14. Evaluation of FEMA-440 for including soil-structure interaction

    Institute of Scientific and Technical Information of China (English)

    Khoshnoudian F.; Behmanesh I.

    2010-01-01

    Replacing the entire soil-structure system with a fixed base oscillator to consider the effect of soil-structure interaction (SSI) is a common analysis method in seismic design. This technique has been included in design procedures such as NEHRP, ASCE, etc. By defining an equivalent fundamental period and damping ratio that can modify the response of the structure. However, recent studies indicate that the effects of SSI should be reconsidered when a structure undergoes a nonlinear displacement demand. In recent documents on Nonlinear Static Procedures (NSPs), FEMA-440 (2005), a modified damping ratio of the replacement oscillator was proposed by introducing the ductility of the soil-structure system obtained from pushover analysis. In this paper, the damping defined in FEMA-440 to include the soil-structure interaction effect is evaluated, and the accuracy of the Coefficiem Method given in FEMA-440 and the Equivalent Linearization Method is studied. Although the improvements for Nonlinear Static Procedures (NSPs) in FEMA-440 are achieved for a fixed base SDOF structure, the soil effects are not perfectly obtained. Furthermore, the damping definition of a soil-structure system is extended to structures to consider bilinear behavior.

  15. Proposal to Include Electrical Energy in the Industrial Return Statistics

    CERN Document Server

    2003-01-01

    At its 108th session on the 20 June 1997, the Council approved the Report of the Finance Committee Working Group on the Review of CERN Purchasing Policy and Procedures. Among other topics, the report recommended the inclusion of utility supplies in the calculation of the return statistics as soon as the relevant markets were deregulated, without reaching a consensus on the exact method of calculation. At its 296th meeting on the 18 June 2003, the Finance Committee approved a proposal to award a contract for the supply of electrical energy (CERN/FC/4693). The purpose of the proposal in this document is to clarify the way electrical energy will be included in future calculations of the return statistics. The Finance Committee is invited: 1. to agree that the full cost to CERN of electrical energy (excluding the cost of transport) be included in the Industrial Service return statistics; 2. to recommend that the Council approves the corresponding amendment to the Financial Rules set out in section 2 of this docum...

  16. Chronic lymphocytic leukemia: a clinical review including Korean cohorts.

    Science.gov (United States)

    Jeon, Young-Woo; Cho, Seok-Goo

    2016-05-01

    Only 5th decade ago, chronic lymphocytic leukemia (CLL) was only recognized as disease group of presenting features like peripheral lymphocytosis, organomegaly including of splenomegaly. As understanding of disease biology and molecular diagnostic tools are getting improved gradually, characterization of variation in CLL's clinical courses was facilitated, resulting in better risk stratification and targeted treatments. Consequently multiple new targeted agents have been used in treatment of CLL, it makes improved clinical outcome. Rituximab containing chemoimmunotherapy (combination of rituximab, fludarabine, and cyclophosphamide) have shown better overall response rate and progression-free survival on fit patients' group in front-line setting, result in standard first-line therapeutic option for CLL. Furthermore, after introducing that the B-cell receptor is crucial for the evolution and progression of CLL, emerging treatments targeting highly activated surface antigens and oncogenic signaling pathways have been associated with several successes in recent decades. These include new anti-CD 20 monoclonal antibody (obinutuzumab), the bruton tyrosine kinase inhibitor (ibrutinib), the phosphatidylinositol 3-kinase inhibitor (idelalisib), and B-cell CLL/lymphoma 2 inhibitor (ABT-199 and ABT-263). So, we discuss not only general pathophysiology of CLL, but also rapidly advancing treatment strategies that are being studied or approved for treatment of CLL. PMID:27044858

  17. Kabuki syndrome: expanding the phenotype to include microphthalmia and anophthalmia.

    Science.gov (United States)

    McVeigh, Terri P; Banka, Siddharth; Reardon, William

    2015-10-01

    Kabuki syndrome is a rare genetic malformation syndrome that is characterized by distinct facies, structural defects and intellectual disability. Kabuki syndrome may be caused by mutations in one of two histone methyltransferase genes: KMT2D and KDM6A. We describe a male child of nonconsanguineous Irish parents presenting with multiple malformations, including bilateral extreme microphthalmia; cleft palate; congenital diaphragmatic hernia; duplex kidney; as well as facial features of Kabuki syndrome, including interrupted eyebrows and lower lid ectropion. A de-novo germline mutation in KMT2D was identified. Whole-exome sequencing failed to reveal mutations in any of the known microphthalmia/anopthalmia genes. We also identified four other patients with Kabuki syndrome and microphthalmia. We postulate that Kabuki syndrome may produce this type of ocular phenotype as a result of extensive interaction between KMT2D, WAR complex proteins and PAXIP1. Children presenting with microphthalmia/anophthalmia should be examined closely for other signs of Kabuki syndrome, especially at an age where the facial gestalt might be less readily appreciable. PMID:26049589

  18. Case studies: Former centrally planned economics, including the Russian Federation

    International Nuclear Information System (INIS)

    The current conditions at former uranium mining sites in the Russian Federation are a direct consequence of the Soviet era operation of uranium mines without effective management of the environmental and social aspects of production and without remediation of contaminated areas, much less planning and design for remediation and long term containment of wastes. Mining operations without environmental protection or closure plans were the normal operating approach in the USA and other western countries but the resulting problems were being recognized in the 1960s and most of the legacy sites have since been cleaned up. Similar operating conditions without effective pollution control and closure concepts prevailed at uranium sites in other centrally planned economies such as the Central Asian Republics, East Germany, Czechoslovakia and Hungary prior to 1990. Currently, many mining areas in eastern and western European countries, including Spain, Hungary and the Czech Republic, have instituted effective remediation standards at major mining sites, including programmes applicable to existing as well as new uranium and other metal mines. These programmes are in areas in which long and active mining traditions provide a set of strong working models for effective environmental controls for current and proposed mines in the Russian Federation and other countries in transition from centrally planned economies. Several community surveys document hundreds of homes with radiation levels as much as 10 to 20 times the level requiring remedial action under international standards acknowledged by Russian investigators. The mining districts of southeastern Chita, (the Russian Federation) including Baley (thorium contamination) and others, reported high indoor radiation areas such as Krasnokamensk and Nerchinsk, which are among the first population exposures to these worldwide problems identified in the Russian Federation. Effective national and international attention to the severity

  19. Visió general de la discussió sobre les àrees d’exclusió del projecte INCLUD-ED General overview of the discussion on exclusion areas in the INCLUD-ED project Visión general de la discusión sobre las áreas de exclusión del proyecto INCLUD-ED

    Directory of Open Access Journals (Sweden)

    Carme García

    2010-01-01

    Full Text Available En aquest article es discuteixen les aportacions que es fan des del projecte INCLUD-ED: Strategies for inclusion and social cohesion from education in Europe sobre la relació que es pot establir entre l’exclusió/inclusió educativa i l’exclusió/inclusió en quatre àrees de la societat: ocupació, habitatge, salut i participació social i política. En particular, es reflexiona sobre els efectes que té tant l’exclusió, com formes de superar-la i promoure la inclusió, en les situacions que han d’afrontar les persones que pertanyen a algun dels cinc grups vulnerables que es defineixen en el projecte INCLUD-ED. Es presenta una visió general de l’estat de la qüestió sobre les investigacions i anàlisis de les àrees d’exclusió. Conclou amb unes breus reflexions sobre com superar les situacions d’exclusió i quines alternatives d’actuació s’obren des de l’àmbit educatiu. ____________________________________________ Dans cet article, nous discutons les contributions que fait le projet INCLUD-ED sur la relation que l’on peut établir entre l’exclusion/inclusion éducative et l’exclusion/inclusion dans quatre domaines de la société : emploi, logement, santé et participation sociale et politique. En particulier, nous réfléchissons sur les effets de l’exclusion ainsi que sur les manières de la dépasser et de promouvoir l’inclusion dans les situations que doivent affronter les individus appartenant à l’un des cinq groupes vulnérables qui sont définis dans le projet INCLUD-ED. Nous présentons une vision générale de l’état de la question sur les recherches et les analyses des domaines d’exclusion. L'article conclut avec de brèves réflexions sur la manière de dépasser les situations d’exclusion et sur les alternatives d’intervention qui s’ouvrent dans le domaine éducatif.In this paper, we discuss the contributions of the INCLUD-ED project to the relationship that can be established

  20. Modeling potentiometric measurements in topological insulators including parallel channels

    Science.gov (United States)

    Hong, Seokmin; Diep, Vinh; Datta, Supriyo; Chen, Yong P.

    2012-08-01

    The discovery of spin-polarized states at the surface of three-dimensional topological insulators (TI) like Bi2Te3 and Bi2Se3 motivates intense interests in possible electrical measurements demonstrating unique signatures of these unusual states. Here we show that a three-terminal potentiometric set-up can be used to probe them by measuring the voltage change of a detecting magnet upon reversing its magnetization. We present numerical results using a nonequilibrium Green's function (NEGF)-based model to show the corresponding signal quantitatively in various transport regimes. We then provide an analytical expression for the resistance (the measured voltage difference divided by an applied current) that agrees with NEGF results well in both ballistic and diffusive limits. This expression is applicable to TI surface states, two-dimensional electrons with Rashba spin-split bands, and any combination of multiple channels, including bulk parallel states in TI, which makes it useful in analyzing experimental results.

  1. Extensions of MAD Version 8 to Include Beam Acceleration

    International Nuclear Information System (INIS)

    In this paper, the authors describe modifications to MAD version 8.23 to include linear accelerator cavities and beam acceleration. An additional energy variable has been added which is modified as the beam passes through LCAV elements (linear accelerator cavities) and can be used as a constraint in matching commands. The calculation of the beta functions and phase advance is consistent with that in other codes that treat acceleration such as TRANSPORT or DIMAD. These modifications allow this version of MAD to be used for the design and modeling of linacs and the authors present examples from the Next Linear Collider design as well as a muon acceleration complex. The code is available from CERN or SLAC

  2. Property transfer assessments should include radon gas testing

    International Nuclear Information System (INIS)

    There are two emerging influences that will require radon gas testing as part of many property transfers and most environmental assessments. These requirements come from lending regulators and state legislatures and affect single family, multifamily, and commercial properties. Fannie Mae and others have developed environmental investigation guidelines for protection from long term legal liabilities in the purchase of environmentally contaminated real estate. These guidelines include radon gas testing for many properties. Several states have enacted laws that require environmental disclosure forms be prepared to ensure that the parties involved in certain real estate transactions are aware of the environmental liabilities that may come with the transfer of property. Indiana has recently enacted legislation that would require the disclosure of the presence of radon gas on many commercial real estate transactions. With more banks and state governments following this trend, radon gas testing should be performed during all property transfers and environmental assessments to protect the parties involved from any long term legal liabilities

  3. Modeling Electric Double-Layers Including Chemical Reaction Effects

    DEFF Research Database (Denmark)

    Paz-Garcia, Juan Manuel; Johannesson, Björn; Ottosen, Lisbeth M.;

    2014-01-01

    A physicochemical and numerical model for the transient formation of an electric double-layer between an electrolyte and a chemically-active flat surface is presented, based on a finite elements integration of the nonlinear Nernst-Planck-Poisson model including chemical reactions. The model works...... for symmetric and asymmetric multi-species electrolytes and is not limited to a range of surface potentials. Numerical simulations are presented, for the case of a CaCO3 electrolyte solution in contact with a surface with rate-controlled protonation/deprotonation reactions. The surface charge and...... potential are determined by the surface reactions, and therefore they depends on the bulk solution composition and concentration...

  4. Molecular phylogeny of coronaviruses including human SARS-CoV

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Phylogenetic tree of coronaviruses (CoVs) including the human SARS-associated virus is reconstructed from complete genomes by using our newly developed K- string composition approach. The relation of the human SARS-CoV to other coronaviruses, i.e. the rooting of the tree is suggested by choosing an appropriate outgroup. SARS-CoV makes a separate group closer but still distant from G2 (CoVs in mammalian host). The relation between different isolates of the human SARS virus is inferred by first constructing an ultrametric distance matrix from counting sequence variations in the genomes. The resulting tree is consistent with clinic relations between the SARS-CoV isolates. In addition to a larger variety of coronavirus genomes these results provide phylogenetic knowledge based on independent novel methodology as compared to recent phylogenetic studies on SARS-CoV.

  5. Numerical modelling of coal spontaneous combustion with moisture included

    Energy Technology Data Exchange (ETDEWEB)

    Arisoy, A. [Istanbul Technical University, Istanbul (Turkey). Mechanical Engineering Faculty

    2005-07-01

    A mathematical model for spontaneous combustion of coal with moisture included is presented. The one-dimensional unsteady state model consists of conservation equations for oxygen, water vapour and inherent moisture of coal and energy for both gaseous and solid phases. A first order Arrhenius reaction rate for oxidation under both pore diffusion and chemically controlled reaction regime is considered. The rate of evaporation or condensation is also considered as a function of temperature of coal, water content of coal and gas streams. The equation of the model is solved numerically by the finite difference technique. Influences of different parameters on the process of spontaneous combustion can be examined by using this model. Also the model can be used to simulate full-scale storage conditions. 4 refs., 5 figs., 1 tab.

  6. OPAL Central Detector (Including vertex, jet and Z chambers)

    CERN Multimedia

    OPAL was one of the four experiments installed at the LEP particle accelerator from 1989 - 2000. OPAL's central tracking system consists of (in order of increasing radius) a silicon microvertex detector, a vertex detector, a jet chamber, and z-chambers. All the tracking detectors work by observing the ionization of atoms by charged particles passing by: when the atoms are ionized, electrons are knocked out of their atomic orbitals, and are then able to move freely in the detector. These ionization electrons are detected in the different parts of the tracking system. (This piece includes the vertex, jet and Z chambers) In the picture above, the central detector is the piece being removed to the right.

  7. Modeling of Electric Double-Layers Including Chemical Reaction Effects

    International Nuclear Information System (INIS)

    A physicochemical and numerical model for the transient formation of an electric double-layer between an electrolyte and a chemically-active flat surface is presented, based on a finite elements integration of the nonlinear Nernst-Planck-Poisson model including chemical reactions. The model works for symmetric and asymmetric multi-species electrolytes and is not limited to a range of surface potentials. Numerical simulations are presented, for the case of a CaCO3 electrolyte solution in contact with a surface with rate-controlled protonation/deprotonation reactions. The surface charge and potential are determined by the surface reactions, and therefore they depend on the bulk solution composition and concentration

  8. PASCAL for engineers: A course including OMEGASOFT PASCAL for microcomputers

    International Nuclear Information System (INIS)

    These are the notes of a PASCAL course for controls engineers at CERN. The course starts with 'Standard Pascal' and includes OMEGASOFT Pascal, a powerful extension of Pascal towards real-time and systems applications. It demonstrates how a language such as Pascal, with adequate extensions for systems programming and embedded microprocessor-driven systems, can substantially increase the productivity of programmers and the reliability of their products. Also enhanced will be the legibility of the programs and their maintainability, since programming in Pascal automatically leads to autodocumentation. Simple examples show how OMEGASOFT-PASCAL can be used for efficient programming of embedded systems for real-time data acquisition and control using the MC6809 microprocessor. (orig.)

  9. Actuator assembly including a single axis of rotation locking member

    Science.gov (United States)

    Quitmeyer, James N.; Benson, Dwayne M.; Geck, Kellan P.

    2009-12-08

    An actuator assembly including an actuator housing assembly and a single axis of rotation locking member fixedly attached to a portion of the actuator housing assembly and an external mounting structure. The single axis of rotation locking member restricting rotational movement of the actuator housing assembly about at least one axis. The single axis of rotation locking member is coupled at a first end to the actuator housing assembly about a Y axis and at a 90.degree. angle to an X and Z axis providing rotation of the actuator housing assembly about the Y axis. The single axis of rotation locking member is coupled at a second end to a mounting structure, and more particularly a mounting pin, about an X axis and at a 90.degree. angle to a Y and Z axis providing rotation of the actuator housing assembly about the X axis. The actuator assembly is thereby restricted from rotation about the Z axis.

  10. Configuration based Collisional-Radiative Model including configuration interaction

    Science.gov (United States)

    Busquet, Michel

    2007-11-01

    Atomic levels mixing through Configuration Interaction (CI) yields important effects. It transfers oscillator strengthes from allowed lines to forbidden lines, and produces strong shift and broadening of line arrays, although the total emissivity is almost insensitive to CI, being proportional to the average wave number. However for hi Z material, like Xe or Sn (potential xuv-ray source for micro-lithography), a non-LTE calculation accounting for all relevant levels wiill be untractable with billions of states. The model we constructed, CAVCRM (caf'e-crème), is a non-LTE C.R.M. where states are configurations but it includes C.I. to give full richness of spectral quantities, using the latest version of the HULLAC-v9 suite of codes and our newly developped algorithm for large set of states with as many as 50,000 states [1]. [1] M.Klapisch et al, this conference

  11. A Case for Including Transactions in OpenMP

    Energy Technology Data Exchange (ETDEWEB)

    Wong, M; Bihari, B L; de Supinski, B R; Wu, P; Michael, M; Liu, Y; Chen, W

    2010-01-25

    Transactional Memory (TM) has received significant attention recently as a mechanism to reduce the complexity of shared memory programming. We explore the potential of TM to improve OpenMP applications. We combine a software TM (STM) system to support transactions with an OpenMP implementation to start thread teams and provide task and loop-level parallelization. We apply this system to two application scenarios that reflect realistic TM use cases. Our results with this system demonstrate that even with the relatively high overheads of STM, transactions can outperform OpenMP critical sections by 10%. Overall, our study demonstrates that extending OpenMP to include transactions would ease programming effort while allowing improved performance.

  12. Relativistic bound state approach to fundamental forces including gravitation

    Directory of Open Access Journals (Sweden)

    Morsch H.P.

    2012-06-01

    Full Text Available To describe the structure of particle bound states of nature, a relativistic bound state formalism is presented, which requires a Lagrangian including scalar coupling of two boson fields. The underlying mechanisms are quite complex and require an interplay of overlapping boson fields and fermion-antifermion production. This gives rise to two potentials, a boson-exchange potential and one identified with the long sought confinement potential in hadrons. With minimal requirements, two elementary massless fermions (quantons - with and without charge - and one gauge boson, hadrons and leptons but also atoms and gravitational systems are described by bound states with electric and magnetic coupling between the charges and spins of quantons. No need is found for colour, Higgs-coupling and supersymmetry.

  13. Ball Screw Actuator Including an Axial Soft Stop

    Science.gov (United States)

    Wingett, Paul T. (Inventor); Forrest, Steven Talbert (Inventor); Abel, Steve (Inventor); Woessner, George (Inventor); Hanlon, Casey (Inventor)

    2016-01-01

    An actuator includes an actuator housing, a ball screw, and an axial soft stop assembly. The ball screw extends through the actuator housing and has a first end and a second end. The ball screw is coupled to receive a drive force and is configured, upon receipt of the drive force, to selectively move in a retract direction and an extend direction. The axial soft stop assembly is disposed within the actuator housing. The axial soft stop assembly is configured to be selectively engaged by the ball screw and, upon being engaged thereby, to translate, with compliance, a predetermined distance in the extend direction, and to prevent further movement of the ball screw upon translating the predetermined distance.

  14. Ball Screw Actuator Including a Stop with an Integral Guide

    Science.gov (United States)

    Wingett, Paul T. (Inventor); Perek, John (Inventor); Geck, Kellan (Inventor)

    2015-01-01

    An actuator includes a housing assembly, a ball nut, a ball screw, and a ball screw stop. The ball nut is rotationally mounted in the housing assembly, is adapted to receive an input torque, and is configured, upon receipt thereof, to rotate and supply a drive force. The ball screw is mounted within the housing assembly and extends through the ball nut. The ball screw has a first end and a second end, and is coupled to receive the drive force from the ball nut. The ball screw is configured, upon receipt of the drive force, to selectively translate between a stow position and a deploy position. The ball screw stop is mounted on the ball screw to translate therewith and is configured to at selectively engage the housing assembly while the ball screw is translating, and engage the ball nut when the ball screw is in the deploy position.

  15. Ball Screw Actuator Including a Compliant Ball Screw Stop

    Science.gov (United States)

    Wingett, Paul T. (Inventor); Hanlon, Casey (Inventor)

    2015-01-01

    An actuator includes a ball nut, a ball screw, and a ball screw stop. The ball nut is adapted to receive an input torque and in response rotates and supplies a drive force. The ball screw extends through the ball nut and has a first end and a second end. The ball screw receives the drive force from the ball nut and in response selectively translates between a retract position and a extend position. The ball screw stop is mounted on the ball screw proximate the first end to translate therewith. The ball screw stop engages the ball nut when the ball screw is in the extend position, translates, with compliance, a predetermined distance toward the first end upon engaging the ball nut, and prevents further rotation of the ball screw upon translating the predetermined distance.

  16. Time-dependent accident sequences including human actions

    International Nuclear Information System (INIS)

    During an accident, transitions between plant states can occur due to operator intervention and the failure of systems while running. The latter cause of transition is much less likely than the first, which includes errors of commission and omission as well as recovery of lost functions. A methodology has been developed to model these transitions in the time domain. As an example, it is applied to the analysis of Three-Mile-Island-type accidents. Statistical evidence is collected and used in assessing the frequency of stuck-open power-operated relief valves at Babcock and Wilcox plants as well as the frequency of misdiagnosis. Statistical data are also used in modeling the timing of operator actions during the accident, i.e., turning off and on the high-pressure injection system and closing the block valves

  17. Thermodynamic analysis of a Stirling engine including regenerator dead volume

    Energy Technology Data Exchange (ETDEWEB)

    Puech, Pascal; Tishkova, Victoria [Universite de Toulouse, UPS, CNRS, CEMES, 29 rue Jeanne Marvig, F-31055 Toulouse (France)

    2011-02-15

    This paper provides a theoretical investigation on the thermodynamic analysis of a Stirling engine with linear and sinusoidal variations of the volume. The regenerator in a Stirling engine is an internal heat exchanger allowing to reach high efficiency. We used an isothermal model to analyse the net work and the heat stored in the regenerator during a complete cycle. We show that the engine efficiency with perfect regeneration doesn't depend on the regenerator dead volume but this dead volume strongly amplifies the imperfect regeneration effect. An analytical expression to estimate the improvement due to the regenerator has been proposed including the combined effects of dead volume and imperfect regeneration. This could be used at the very preliminary stage of the engine design process. (author)

  18. Hydraulic engine valve actuation system including independent feedback control

    Science.gov (United States)

    Marriott, Craig D

    2013-06-04

    A hydraulic valve actuation assembly may include a housing, a piston, a supply control valve, a closing control valve, and an opening control valve. The housing may define a first fluid chamber, a second fluid chamber, and a third fluid chamber. The piston may be axially secured to an engine valve and located within the first, second and third fluid chambers. The supply control valve may control a hydraulic fluid supply to the piston. The closing control valve may be located between the supply control valve and the second fluid chamber and may control fluid flow from the second fluid chamber to the supply control valve. The opening control valve may be located between the supply control valve and the second fluid chamber and may control fluid flow from the supply control valve to the second fluid chamber.

  19. The Physics of Semiconductors An Introduction Including Nanophysics and Applications

    CERN Document Server

    Grundmann, Marius

    2010-01-01

    The Physics of Semiconductors contains ample material for a comprehensive upper-level undergraduate or beginning graduate course, guiding readers to the point where they can choose a special topic and begin supervised research. The textbook provides a balance between essential aspects of solid-state and semiconductor physics, on the one hand, and the principles of various semiconductor devices and their applications in electronic and photonic devices, on the other. It highlights many practical aspects of semiconductors such as alloys, strain, heterostructures, nanostructures, that are necessary in modern semiconductor research but typically omitted in textbooks. Coverage also includes additional advanced topics, such as Bragg mirrors, resonators, polarized and magnetic semiconductors. The text derives explicit formulas for many results to support better understanding of the topics. The Physics of Semiconductors requires little or no prior knowledge of solid-state physics and evolved from a highly regarded two...

  20. Traversing Cosmological Singularities, Complete Journeys Through Spacetime Including Antigravity

    CERN Document Server

    Bars, Itzhak

    2012-01-01

    A unique description of the Big Crunch-Big Bang transition is given at the classical gravity level, along with a complete set of homogeneous, isotropic, analytic solutions in scalar-tensor cosmology, with radiation and curvature. All solutions repeat cyclically; they have been obtained by using conformal gauge symmetry (Weyl symmetry) as a powerful tool in cosmology, and more generally in gravity. The significance of the Big Crunch-Big Bang transition is that it provides a model independent analytic resolution of the singularity, as an unambiguous and unavoidable solution of the equations at the classical gravitational physics level. It is controlled only by geometry (including anisotropy) and only very general features of matter coupled to gravity, such as kinetic energy of a scalar field, and radiation due to all forms of relativistic matter. This analytic resolution of the singularity is due to an attractor mechanism created by the leading terms in the cosmological equation. It is unique, and it is unavoid...

  1. Recent progress and advances in iterative software (including parallel aspects)

    Energy Technology Data Exchange (ETDEWEB)

    Carey, G.; Young, D.M.; Kincaid, D. [and others

    1994-12-31

    The purpose of the workshop is to provide a forum for discussion of the current state of iterative software packages. Of particular interest is software for large scale engineering and scientific applications, especially for distributed parallel systems. However, the authors will also review the state of software development for conventional architectures. This workshop will complement the other proposed workshops on iterative BLAS kernels and applications. The format for the workshop is as follows: To provide some structure, there will be brief presentations, each of less than five minutes duration and dealing with specific facets of the subject. These will be designed to focus the discussion and to stimulate an exchange with the participants. Issues to be covered include: The evolution of iterative packages, current state of the art, the parallel computing challenge, applications viewpoint, standards, and future directions and open problems.

  2. Cellular automata simulation of traffic including cars and bicycles

    Science.gov (United States)

    Vasic, Jelena; Ruskin, Heather J.

    2012-04-01

    As 'greening' of all aspects of human activity becomes mainstream, transportation science is also increasingly focused around sustainability. Modal co-existence between motorised and non-motorised traffic on urban networks is, in this context, of particular interest for traffic flow modelling. The main modelling problems here are posed by the heterogeneity of vehicles, including size and dynamics, and by the complex interactions at intersections. Herein we address these with a novel technique, based on one-dimensional cellular automata components, for modelling network infrastructure and its occupancy by vehicles. We use this modelling approach, together with a corresponding vehicle behaviour model, to simulate combined car and bicycle traffic for two elemental scenarios-examples of components that would be used in the building of an arbitrary network. Results of simulations performed on these scenarios, (i) a stretch of road and (ii) an intersection causing conflict between cars and bicycles sharing a lane, are presented and analysed.

  3. The physics of semiconductors an introduction including nanophysics and applications

    CERN Document Server

    Grundmann, Marius

    2016-01-01

    The 3rd edition of this successful textbook contains ample material for a comprehensive upper-level undergraduate or beginning graduate course, guiding readers to the point where they can choose a special topic and begin supervised research. The textbook provides a balance between essential aspects of solid-state and semiconductor physics, on the one hand, and the principles of various semiconductor devices and their applications in electronic and photonic devices, on the other. It highlights many practical aspects of semiconductors such as alloys, strain, heterostructures, nanostructures, that are necessary in modern semiconductor research but typically omitted in textbooks. Coverage also includes additional advanced topics, such as Bragg mirrors, resonators, polarized and magnetic semiconductors, nanowires, quantum dots, multi-junction solar cells, thin film transistors, carbon-based nanostructures and transparent conductive oxides. The text derives explicit formulas for many results to support better under...

  4. The action principle for generalized fluid motion including gyroviscosity

    International Nuclear Information System (INIS)

    Highlights: • Method for constructing action principles for a diverse class of fluids with gyroscopic momentum transport is described. • General criteria for the conservation of momentum and angular momentum via Noether's theorem are obtained. • Fluids with intrinsic angular momentum are built as an illustration of the method. - Abstract: A general set of fluid equations that allow for energy-conserving momentum transport by gyroscopic motion of fluid elements is obtained. The equations are produced by a class of action principles that yield a large subset of the known fluid and magnetofluid models, including gyroviscosity. Analysis of the action principle yields broad, model-independent results regarding the conservation laws of energy and linear and angular momenta. The formalism is illustrated by studying fluid models with intrinsic angular momentum that may appear in the contexts of condensed matter, biological, and other areas of physics

  5. CHIONANTHUS (OLEACEAE IN SULAWESI, INDONESIA, INCLUDING THREE NEW SPECIES

    Directory of Open Access Journals (Sweden)

    RUTH KIEW

    2016-01-01

    Full Text Available KIEW, R. 2015. Chionanthus (Oleaceae in Sulawesi, Indonesia, including three new species. Reinwardtia 14(2: 287 ‒295. ― The genus Chionanthus (Oleaceae in Sulawesi is revised. Nine species are described of which C. kostermansiiKiew, C. sordidus Kiew and C. sulawesicus Kiew are new species. Four species are endemic, C. celebicus Koord., C.sordidus, C. stenurus (Merr. Kiew and C. sulawesicus. The geographic range of C. cordulatus Koord. extends to Borneoand Mollucas, while C. kostermansii also occurs in Sumbawa and Flores, and the range of C. rupicolus (Lingelsh.Kiew extends to Sumbawa, Mollucas, New Guinea and the Bismarck Archipelago. Chionanthus polygamus (Roxb.Kiew and C. ramiflorus Roxb. are both widespread species, the former from Sumatra to New Guinea and the latter fromcontinental Asia to the Solomon Islands. A key to identify the species is provided. Chionanthus gigantifolius Koord.remains incompletely known.

  6. Neutrinos from Cosmic Accelerators including Magnetic Field and Flavor Effects

    Directory of Open Access Journals (Sweden)

    Walter Winter

    2012-01-01

    Full Text Available We review the particle physics ingredients affecting the normalization, shape, and flavor composition of astrophysical neutrinos fluxes, such as different production modes, magnetic field effects on the secondaries (muons, pions, and kaons, and flavor mixing, where we focus on pγ interactions. We also discuss the interplay with neutrino propagation and detection, including the possibility to detect flavor and its application in particle physics, and the use of the Glashow resonance to discriminate pγ from pp interactions in the source. We illustrate the implications on fluxes and flavor composition with two different models: (1 the target photon spectrum is dominated by synchrotron emission of coaccelerated electrons and (2 the target photon spectrum follows the observed photon spectrum of gamma-ray bursts. In the latter case, the multimessenger extrapolation from the gamma-ray fluence to the expected neutrino flux is highlighted.

  7. Improving Planck calibration by including frequency-dependent relativistic corrections

    CERN Document Server

    Quartin, Miguel

    2015-01-01

    The Planck satellite detectors are calibrated in the 2015 release using the "orbital dipole", which is the time-dependent dipole generated by the Doppler effect due to the motion of the satellite around the Sun. Such an effect has also relativistic time-dependent corrections of relative magnitude 10^(-3), due to coupling with the "solar dipole" (the motion of the Sun compared to the CMB rest frame), which are included in the data calibration by the Planck collaboration. We point out that such corrections are subject to a frequency-dependent multiplicative factor. This factor differs from unity especially at the highest frequencies, relevant for the HFI instrument. Since currently Planck calibration errors are dominated by systematics, to the point that polarization data is currently unreliable at large scales, such a correction can in principle be highly relevant for future data releases.

  8. Goldilocks Models of Higher-Dimensional Inflation (including modulus stabilization)

    CERN Document Server

    Burgess, C P; Hayman, Peter; Patil, Subodh P

    2016-01-01

    We explore the mechanics of inflation in simplified extra-dimensional models involving an inflaton interacting with the Einstein-Maxwell system in two extra dimensions. The models are Goldilocks-like in that they are just complicated enough to include a mechanism to stabilize the extra-dimensional size, yet simple enough to solve the full 6D field equations using basic tools. The solutions are not limited to the effective 4D regime with H m_KK, but when they do standard 4D fluctuation calculations need not apply. When in a 4D regime the solutions predict eta ~ 0 hence n_s ~ 0.96 and r ~ 0.096 and so are ruled out if tensor modes remain unseen. Analysis of general parameters is difficult without a full 6D fluctuation calculation.

  9. Fuel cell repeater unit including frame and separator plate

    Science.gov (United States)

    Yamanis, Jean; Hawkes, Justin R; Chiapetta, Jr., Louis; Bird, Connie E; Sun, Ellen Y; Croteau, Paul F

    2013-11-05

    An example fuel cell repeater includes a separator plate and a frame establishing at least a portion of a flow path that is operative to communicate fuel to or from at least one fuel cell held by the frame relative to the separator plate. The flow path has a perimeter and any fuel within the perimeter flow across the at least one fuel cell in a first direction. The separator plate, the frame, or both establish at least one conduit positioned outside the flow path perimeter. The conduit is outside of the flow path perimeter and is configured to direct flow in a second, different direction. The conduit is fluidly coupled with the flow path.

  10. Loan Products Included in the Offer of Commercial Banks

    Directory of Open Access Journals (Sweden)

    Vasile Dedu

    2009-04-01

    Full Text Available A bank loan is the main form of economical credit. It is for corporate activities – for medium and big companies and for retail activities – for small companies and individuals. The conditions for credit mainly depend on the quality of customers, it means their ability to perform a profitable activity and to be able to pay back the credits. For reasons which are mainly connected to marketing, bank practice has developed a large range of credit names, trying to emphasize some of the parts of the products or to take profit of some competition advantages in relation with customers’ products. We are trying to include the offer of bank loans in a typology which takes into account the law, the bank field rules and the main technical features of the offered products.

  11. SIMS analysis of insulating multilayer including silicon nitride

    International Nuclear Information System (INIS)

    We developed a new sample preparation method for thick insulating samples in secondary ion mass spectrometry (SIMS) analyses. In power semiconductor devices, impurity analyses in passivation layers and sealing resins are very important. SIMS analyses are suitable for this purpose, but in SIMS analysis of insulating samples, charging up would be a serious problem. Previous methods are not efficient enough to avoid the charging up of thick insulating sample, such as passivation layers. In this new technique of sample preparation, we made trenches by a FIB Ga beam, and filled them up with Pt. Including these Pt lines into the raster area, the charge of the sample can flow away through these lines during SIMS analysis. We applied this method to SiN/Si samples and confirmed that embedded Pt lines were effective for preventing the charging up

  12. Leach method including means to protect ion exchange resin

    International Nuclear Information System (INIS)

    A method for recovering uranium and/or related values which include means for protecting ion-exchange resins in the recovery operation from oxidative degradation due to contact with hydrogen peroxide. A guard chamber is positioned in the elution circuit so that barren eluant, after it is stripped of its uranium and/or related values by treatment with hydrogen peroxide, will flow through the chamber. The guard chamber contains catalytic material, e.g. activated carbon, which decomposes hydrogen peroxide upon contact into water and oxygen. The barren eluant, after it passes through the catalytic material, is used to make up fresh eluant for reuse in the recovery method without the risk of the fresh eluant causing oxidative degradation of the resins

  13. Terrorism cover in France for property damage including nuclear risks

    International Nuclear Information System (INIS)

    The obligation to include terrorism cover in all Property Damage policies issued on the French Market is ruled by an Act of 1986 and introduced under Section R 126-2 of the French Code of Insurance. This section stipulates that Property Damage policies must provide cover for damage resulting from acts of terrorism, with the same deductible and the same limit than that of the other damage covered in the policy. Soon after the dramatic events of September 11, 2001 in the United States and although reinsurers worldwide restricted their offer of capacities, French insurers recognized that they had to maintain this global cover for the benefit of their insurers. After difficult discussions between insurers, reinsurers, brokers, risk managers and representatives of the State, the creation of a new Pool, backed with a State guarantee, was decided in less than three months. Effective January 1, 2002 and called Gestion d'Assurance et de Reassurance des Risques Attentats et Actes de Terrorisme (GAREAT), the Pool offers a multiple layers stop-loss cover for Property Damage only, i.e. excluding TPL policies. Considering that nuclear risks should be treated in the same way as other industrial risks, it was decided that they would be covered by GAREAT as well. In the meantime, by a Decree of December 28, 2001 modifying Section R 126-2, a special provision, aiming at reducing the limit and thus the price of this cover, was introduced in the Code. The purpose of this paper is to expose the present situation applying through GAREAT and, after two years of operation to discuss future developments, including other sources of capacity for the coverage of acts of terrorism in nuclear risks insurance.(author)

  14. Including a learner with physical disabilities: stressful for teachers?

    Directory of Open Access Journals (Sweden)

    I. Eloff

    2002-08-01

    Full Text Available Learners with physical disabilities have been entering mainstream schools for some years now. Whereas early research on inclusive education necessitated a strong focus on the needs of the learners, there has also been a recent interest in the role of the teachers in inclusive education. By adopting constructivism as the paradigm for inquiry a study was undertaken to establish the stress factors for teachers who have to include a learner with a physical disability in their mainstream classes. The rationale for the study is threefold: i Learners with physical disabilities are entering mainstream schools increasingly, ii it is often assumed that inclusive education is too stressful for teachers to cope with, and iii related research has shown that increased contact with individuals with disabilities has a positive effect on attitudes towards individuals with disabilities. In accordance with the dialectical methodology of constructivism, the Teacher Stress and Coping Questionnaire and in-depth interviews were utilised to establish the stress factors and the extent of the stress factors that may be present. The aim of the constructivist inquiry process is to promote understanding and reconstruction. In this article the quantitative results indicate overall low or non-existent levels of stress in teachers who have to include a learner with a physical disability, and the results therefore contribute to our understanding of this situation. The qualitative results reconstruct the meanings that these teachers attach to the inclusion of a learner with a physical disability and reveal some albeit limited concerns about the communication processes between parents and teachers and a perceived lack of pre-service training.

  15. Metal ions affecting the gastrointestinal system including the liver.

    Science.gov (United States)

    Naughton, Declan P; Nepusz, Tamás; Petroczi, Andrea

    2011-01-01

    In the present context, metal ions can be categorized into several classes including those that are essential for life and those that have no known biological function and thus can be considered only as potentially hazardous. Many complexities arise with regard to metal toxicity and there is a paucity of studies relating to many metals which are frequent components of the diet. For many people ingestion of mineral supplements is considered a risk-free health choice despite growing evidence to the contrary. Numerous approaches have been developed to assess risk associated with ingestion of metal ions. These include straightforward estimation of safe limits such as oral reference dose which are often based on data derived from animal experiments. More convoluted approaches such as the Target Hazard Quotient involve assessment of hazard with frequent exposure over long durations such as a lifetime. The latter calculation also affords facile consideration of the effects of many metals together. In many cases, rigorous data are unavailable, hence, large factors of uncertainty are employed to relate risk to humans. Owing to the nature of metal toxicity, data pertaining to the gastrointestinal tract and liver are often acquired from diseases of metal homeostasis or episodes of considerable metal overload. Whilst these studies provide evidence for mechanisms of metal-induced toxicity such as enhancing oxidative stress, extrapolation of these results to healthy individuals or patients with chronic inflammatory diseases is not straightforward. In summary, the diverse nature of metals and their effects on human tissues along with a paucity of studies on the full range of their effects, warrant further in-depth studies on the association of metals to ageing, chronic inflammatory diseases, and cancer. PMID:21473378

  16. Epithelioid Schwannomas: An Analysis of 58 Cases Including Atypical Variants.

    Science.gov (United States)

    Hart, Jesse; Gardner, Jerad M; Edgar, Mark; Weiss, Sharon W

    2016-05-01

    The histologic features and outcome of 58 cases of epithelioid schwannoma were studied to determine the significance of atypical histologic features. Cases were retrieved from personal consultation files from 1999 to 2013. Patients (31 male and 26 female patients) ranged in age from 14 to 80 years (median, 38 y). Two patients had schwannomatosis 1. Tumors developed in the dermis/subcutis (n=56) or muscle (n=2) of the upper extremity (34.5%), lower extremity (34.5%), thorax/abdomen/back (18%), and less common anatomic locations including the scalp, neck, lip, and breast. They ranged in size from 0.25 to 4.5 cm (median, 2.0 cm). Typically circumscribed and surrounded by a perineurium, they comprised single or small groups of epithelioid schwann cells with a moderate amphophilic cytoplasm and occasional nuclear pseudoinclusions. Stroma varied from myxoid to hyalinized, often with thick-walled vessels (55 cases). Mitotic rate ranged from 0 to 9 mitoses/10 high-power field (HPF) (2.37 mm) in the most active areas (mean, 2 to 3 mitoses/10 HPFs). Thirteen cases (22%) were "atypical," defined by a high mitotic rate (≥3 mitoses per 10 HPFs) and nuclear size variation (≥3:1). All (56/56) expressed S100 protein; type IV collagen invested groups or individual cells (16/17). Melanoma markers were negative, except for melan A (1 case). Follow-up in 39 patients (median, 78 mo; range, 6 to 174 mo) indicated that 31 (79%) were alive without disease (including 9/13 atypical cases; median, 78 mo), 7 (18%) were alive with unknown status, and 1 patient had died of unrelated causes. One tumor recurred, but none metastasized. Epithelioid schwannomas, even those with atypical features, are benign and do not constitute a histologic continuum with epithelioid malignant peripheral nerve sheath tumors, which typically occur in deep soft tissues and have more anaplastic features. PMID:26752543

  17. Core training in surgery: what does it need to include?

    Science.gov (United States)

    Potts, John R

    2006-12-01

    Core training for surgeons in any surgical specialty should include education in the relevant basic science knowledge, training in fundamental diagnostic skills, the development of surgical technical skills and considerable experience in patient care. However, for a number of reasons it is no longer acceptable to guide such training based only on such broad goals, not the least of which is the advent of resident duty-hour limitations that make it unrealistic to expect residents to simply acquire, by random observation and participation, all of the important elements of their future practices. Rather, it is necessary to provide a curriculum of learning opportunities specifically structured to allow them to gain the requisite knowledge and skills. Thus, the curriculum for the core surgical training of future vascular surgeons should be based on a very specific learning objectives, stating what information is to be learned or what action is to be done, under what conditions they are to be performed, and what criteria will be used to ascertain the acquisition of the necessary knowledge or skill. Next, the best methods of instruction, including reading materials, lectures, and exposure to specific surgical procedures must be defined and the appropriate instructional materials identified, selecting the best of existing materials or, if necessary, creating them. Finally, the residents' acquisition of knowledge and skills must be assessed. Previously this occurred through a loose combination of performance evaluations from clinical rotations, faculty group discussions, and annual in-training exams culminated in the American Board of Surgery certification process. Now evaluation must relate to specific educational objectives. This is all a daunting task currently being undertaken by vascular surgery program directors, albeit with input from the Residency Review Committee and the Vascular Surgery Board of the American Board of Surgery. Eventually, overall surgical curriculum

  18. Solving the high energy evolution equation including running coupling corrections

    International Nuclear Information System (INIS)

    We study the solution of the nonlinear Balitsky-Kovchegov evolution equation with the recently calculated running coupling corrections [I. I. Balitsky, Phys. Rev. D 75, 014001 (2007). and Y. Kovchegov and H. Weigert, Nucl. Phys. A784, 188 (2007).]. Performing a numerical solution we confirm the earlier result of Albacete et al. [Phys. Rev. D 71, 014003 (2005).] (obtained by exploring several possible scales for the running coupling) that the high energy evolution with the running coupling leads to a universal scaling behavior for the dipole-nucleus scattering amplitude, which is independent of the initial conditions. It is important to stress that the running coupling corrections calculated recently significantly change the shape of the scaling function as compared to the fixed coupling case, in particular, leading to a considerable increase in the anomalous dimension and to a slow-down of the evolution with rapidity. We then concentrate on elucidating the differences between the two recent calculations of the running coupling corrections. We explain that the difference is due to an extra contribution to the evolution kernel, referred to as the subtraction term, which arises when running coupling corrections are included. These subtraction terms were neglected in both recent calculations. We evaluate numerically the subtraction terms for both calculations, and demonstrate that when the subtraction terms are added back to the evolution kernels obtained in the two works the resulting dipole amplitudes agree with each other. We then use the complete running coupling kernel including the subtraction term to find the numerical solution of the resulting full nonlinear evolution equation with the running coupling corrections. Again the scaling regime is recovered at very large rapidity with the scaling function unaltered by the subtraction term

  19. Strategies for replacement of obsolete equipment, including reverse engineering

    International Nuclear Information System (INIS)

    The presentation shall detail the challenges facing nuclear power plants with the replacement of obsolete equipment and the strategies used to overcome those challenges. The presentation will outline the common equipment types which are either obsolete or are becoming obsolete, with a focus on safety related components. The four options of the obsolete equipment replacement philosophy will be presented with replacement examples from each of the options shown for discussion purposes. Detailed examples from each of the four obsolete equipment replacement options of, (1) commercially available equivalent component, (2) modification of a commercial available component, (3) reverse engineering of the original component and finally (4) design changes using a new component, shall be presented to evaluate the advantages and disadvantages of each option. The presentation will include the technical challenges, cost and schedule concerns for each of the four options. Emphasis will be placed on the technological challenges associated with replacing old and obsolete equipment. The following is a bullet list of the challenges which will be discussed: 1) Missing, misleading or no information on the original component. 2) Acquiring information from the original equipment manufacturer and the plant. 3) Using a sample component for the replacement evaluation and or reverse engineering. 4) Reverse engineering old equipment with newly available discrete components. The presentation will include the equivalency documentation using the EPRI guidelines when replacing an original component with a different yet form, fit and functional equivalent component. The presentation will conclude with a discussion of the advantages and disadvantages of the replacement of the obsolete component with a form, fit and functional equivalent component vs. the replacement of the original component with a new component with today's technology. (author)

  20. Strategies for replacement of obsolete equipment - including reverse engineering

    International Nuclear Information System (INIS)

    The presentation shall detail the challenges facing nuclear power plants with the replacement of obsolete equipment and the strategies used to overcome those challenges. The presentation will outline the common equipment types which are either obsolete or are becoming obsolete, with a focus on safety related components. The four options of the obsolete equipment replacement philosophy will be presented with replacement examples from each of the options shown for discussion purposes. Detailed examples from each of the four obsolete equipment replacement options of: commercially available equivalent component; modification of a commercial available component; reverse engineering of the original component; and finally, design changes using a new component, shall be presented to evaluate the advantages and disadvantages of each option. The presentation will include the technical challenges, cost and schedule concerns for each of the four options. Emphasis will be placed on the technological challenges associated with replacing old and obsolete equipment. The following is a bullet list of the challenges which will be discussed: Missing, misleading or no information on the original component; Acquiring information from the original equipment manufacturer and the plant; Using a sample component for the replacement evaluation and or reverse engineering; and Reverse engineering old equipment with newly available discrete components. The presentation will include the equivalency documentation using the EPRI guidelines when replacing an original component with a different yet form, fit and functional equivalent component. The presentation will conclude with a discussion of the advantages and disadvantages of the replacement of the obsolete component with a form, fit and functional equivalent component vs. the replacement of the original component with a new component with today's technology. (author)

  1. Designing monitoring programs for chemicals of emerging concern in potable reuse ⋯ What to include and what not to include?

    KAUST Repository

    Drewes, Jorg

    2012-11-01

    This study discussed a proposed process to prioritize chemicals for reclaimed water monitoring programs, selection of analytical methods required for their quantification, toxicological relevance of chemicals of emerging concern regarding human health, and related issues. Given that thousands of chemicals are potentially present in reclaimed water and that information about those chemicals is rapidly evolving, a transparent, science-based framework was developed to guide prioritization of which compounds of emerging concern (CECs) should be included in reclaimed water monitoring programs. The recommended framework includes four steps: (1) compile environmental concentrations (e.g., measured environmental concentration or MEC) of CECs in the source water for reuse projects; (2) develop a monitoring trigger level (MTL) for each of these compounds (or groups thereof) based on toxicological relevance; (3) compare the environmental concentration (e.g., MEC) to the MTL; CECs with a MEC/MTL ratio greater than 1 should be prioritized for monitoring, compounds with a ratio less than \\'1\\' should only be considered if they represent viable treatment process performance indicators; and (4) screen the priority list to ensure that a commercially available robust analytical method is available for that compound. © IWA Publishing 2013.

  2. Seabrook Station Level 2 PRA Update to Include Accident Management

    International Nuclear Information System (INIS)

    A ground-breaking study was recently completed as part of the Seabrook Level 2 PRA update. This study updates the post-core damage phenomena to be consistent with the most recent information and includes accident management activities that should be modeled in the Level 2 PRA. Overall, the result is a Level 2 PRA that fully meets the requirements of the ASME PRA Standard with respect to modeling accident management in the LERF assessment and NRC requirements in Regulatory Guide 1.174 for considering late containment failures. This technical paper deals only with the incorporation of operator actions into the Level 2 PRA based on a comprehensive study of the Seabrook Station accident response procedures and guidance. The paper describes the process used to identify the key operator actions that can influence the Level 2 PRA results and the development of success criteria for these key operator actions. This addresses a key requirement of the ASME PRA Standard for considering SAMG. An important benefit of this assessment was the identification of Seabrook specific accident management insights that can be fed back into the Seabrook Station accident management procedures and guidance or the training provided to plant personnel for these procedures and guidance. (authors)

  3. ERA's Open Rotor Studies Including Shielding for Noise Reduction

    Science.gov (United States)

    Van Zante, Dale; Thomas, Russell

    2012-01-01

    The Open Rotor is a modern version of the UnDucted Fan (UDF) that was flight tested in the late 1980's through a partnership between NASA and General Electric (GE). Tests were conducted in the 9' x 15' Low Speed Wind Tunnel and the 8' x 6' Supersonic Wind Tunnel starting in late 2009 and completed in early 2012. Aerodynamic and acoustic data were obtained for takeoff, approach and cruise simulations. GE was the primary partner, but other organizations were involved such as Boeing and Airbus who provided additional hardware for fuselage simulations. This test campaign provided the acoustic and performance characteristics for modern open rotor blades designs." NASA and GE conducted joint systems analysis to evaluate how well new blade designs would perform on a B737 class aircraft, and compared the results to an advanced higher bypass ratio turbofan." Acoustic shielding experiments were performed at NASA GRC and Boeing LSAF facilities to provide data for noise estimates of unconventional aircraft configurations with Open Rotor propulsion systems." The work was sponsored by NASA's aeronautics programs, including the Subsonic Fixed Wing (SFW) and the Environmentally Responsible Aviation (ERA) projects."

  4. Developing standard transmission system for radiology reporting including key images

    International Nuclear Information System (INIS)

    Development of hospital information system and Picture Archiving Communication System is not new in the medical field, and the development of internet and information technology are also universal. In the course of such development, however, it is hard to share medical information without a refined standard format. Especially in the department of radiology, the role of PACS has become very important in interchanging information with other disparate hospital information systems. A specific system needs to be developed that radiological reports are archived into a database efficiently. This includes sharing of medical images. A model is suggested in this study in which an internal system is developed where radiologists store necessary images and transmit them is the standard international clinical format, Clinical Document Architecture, and share the information with hospitals. CDA document generator was made to generate a new file format and separate the existing storage system from the new system. This was to ensure the access to required data in XML documents. The model presented in this study added a process where crucial images in reading are inserted in the CDA radiological report generator. Therefore, this study suggests a storage and transmission model for CDA documents, which is different from the existing DICOM SR. Radiological reports could be better shared, when the application function for inserting images and the analysis of standard clinical terms are completed

  5. Polycrystalline-Diamond MEMS Biosensors Including Neural Microelectrode-Arrays

    Directory of Open Access Journals (Sweden)

    Donna H. Wang

    2011-08-01

    Full Text Available Diamond is a material of interest due to its unique combination of properties, including its chemical inertness and biocompatibility. Polycrystalline diamond (poly-C has been used in experimental biosensors that utilize electrochemical methods and antigen-antibody binding for the detection of biological molecules. Boron-doped poly-C electrodes have been found to be very advantageous for electrochemical applications due to their large potential window, low background current and noise, and low detection limits (as low as 500 fM. The biocompatibility of poly-C is found to be comparable, or superior to, other materials commonly used for implants, such as titanium and 316 stainless steel. We have developed a diamond-based, neural microelectrode-array (MEA, due to the desirability of poly-C as a biosensor. These diamond probes have been used for in vivo electrical recording and in vitro electrochemical detection. Poly-C electrodes have been used for electrical recording of neural activity. In vitro studies indicate that the diamond probe can detect norepinephrine at a 5 nM level. We propose a combination of diamond micro-machining and surface functionalization for manufacturing diamond pathogen-microsensors.

  6. Advocacy for women's health should include lesbian health.

    Science.gov (United States)

    O'Hanlan, Katherine A; Dibble, Suzanne L; Hagan, H Jennifer J; Davids, Rachel

    2004-03-01

    Although research confirms that homosexuality is a normal expression of human sexuality, established scientific studies are often not reflected in laws and judicial opinions for lesbians with regard to employment, taxation, pensions, disability, healthcare, immigration, military service, marriage, custody, and adoption. The expression of homosexual attraction or behavior is sometimes met by disdain or violence. Psychological and epidemiological research confirms that the public discriminatory attitudes and second-class legal status cause physical, emotional, and financial harm to lesbians, their families, and their children. Some lesbians experience discrimination in healthcare and avoid routine primary healthcare. To decrease the harm, and improve the health of lesbians, medical institutions can include sexual orientation and gender identity in their nondiscrimination policies and offer domestic partner coverage in employment benefits. Our specialty societies should review current laws and judicial opinions and advocate for change. Further, specialty societies can effect change by issuing policy statements about issues of orientation and by writing orientation/identity curricula for public schools, colleges, and postcollegiate education to improve their accuracy, reduce sexually transmitted diseases, delay sexual activity, and reduce morbidity from homophobic violence. PMID:15072737

  7. A Reformed CDM - including new mechanisms for sustainable development

    Energy Technology Data Exchange (ETDEWEB)

    Holm Olsen, K.; Fenhann, J.

    2009-07-01

    The annual CD4CDM Perspectives Series features a topic of pivotal importance to the global carbon market. The series seeks to communicate the diverse insights and visions of leading actors in the carbon market to better inform the decisions of professionals and policymakers in developing countries. The second theme of the series focuses on how the CDM can be reformed in a post-2012 climate regime, including new mechanism for sustainable development. Seventeen contributors from the private sector, Designated National Authorities, the Executive Board, research, and development agencies present their perspective on meeting challenges such as the unequal regional distribution of CDM projects, concerns about environmental integrity and technology transfer, complex governance procedures, and questions about the CDM's contribution to sustainable development. The new ideas and solutions to these challenges proposed by the authors in this edition of Perspectives have been solicited to help professionals and policy makers make the best decisions in the lead-up to COP 15 in Copenhagen and beyond. (au)

  8. A design of a computer complex including vector processors

    International Nuclear Information System (INIS)

    We, members of the Computing Center, Japan Atomic Energy Research Institute have been engaged for these six years in the research of adaptability of vector processing to large-scale nuclear codes. The research has been done in collaboration with researchers and engineers of JAERI and a computer manufacturer. In this research, forty large-scale nuclear codes were investigated from the viewpoint of vectorization. Among them, twenty-six codes were actually vectorized and executed. As the results of the investigation, it is now estimated that about seventy percents of nuclear codes and seventy percents of our total amount of CPU time of JAERI are highly vectorizable. Based on the data obtained by the investigation, (1)currently vectorizable CPU time, (2)necessary number of vector processors, (3)necessary manpower for vectorization of nuclear codes, (4)computing speed, memory size, number of parallel 1/0 paths, size and speed of 1/0 buffer of vector processor suitable for our applications, (5)necessary software and operational policy for use of vector processors are discussed, and finally (6)a computer complex including vector processors is presented in this report. (author)

  9. Interim performance criteria for photovoltaic energy systems. [Glossary included

    Energy Technology Data Exchange (ETDEWEB)

    DeBlasio, R.; Forman, S.; Hogan, S.; Nuss, G.; Post, H.; Ross, R.; Schafft, H.

    1980-12-01

    This document is a response to the Photovoltaic Research, Development, and Demonstration Act of 1978 (P.L. 95-590) which required the generation of performance criteria for photovoltaic energy systems. Since the document is evolutionary and will be updated, the term interim is used. More than 50 experts in the photovoltaic field have contributed in the writing and review of the 179 performance criteria listed in this document. The performance criteria address characteristics of present-day photovoltaic systems that are of interest to manufacturers, government agencies, purchasers, and all others interested in various aspects of photovoltaic system performance and safety. The performance criteria apply to the system as a whole and to its possible subsystems: array, power conditioning, monitor and control, storage, cabling, and power distribution. They are further categorized according to the following performance attributes: electrical, thermal, mechanical/structural, safety, durability/reliability, installation/operation/maintenance, and building/site. Each criterion contains a statement of expected performance (nonprescriptive), a method of evaluation, and a commentary with further information or justification. Over 50 references for background information are also given. A glossary with definitions relevant to photovoltaic systems and a section on test methods are presented in the appendices. Twenty test methods are included to measure performance characteristics of the subsystem elements. These test methods and other parts of the document will be expanded or revised as future experience and needs dictate.

  10. Including test errors in evaluating surveillance test intervals

    International Nuclear Information System (INIS)

    To evaluate the risk impact of surveillance requirements defined in Technical Specifications, both the beneficial and negative effects of surveillance should be considered. The negative effect of surveillance testing can be caused by test errors, e.g., human errors of omission or commission including potential for common cause failures. As a consequence of the negative effect, the performance of periodic testing can have adverse impact on safety. This paper defines the various negative effects of surveillance testing from a risk perspective, and then presents a methodology to quantify the negative risk impact, i.e., the risk penalty or risk increase caused by the test. The paper presents a PRA-based method to evaluate the negative risk impact due to test-caused plant transients and a method based on a test-caused equipment degradation model and PRA to assess the negative risk impact associated with equipment wear-out. Also described in the paper are illustrative applications of the methods to specific surveillance tests conducted at boiling water reactors (BWRs) such as the tests of main steam isolation valves (MSIVs), turbine overspeed protection system, and diesel generators. Evaluation results of the risk effectiveness of the tests are presented along with the insights from the sensitivity analysis of the risk impact versus test interval

  11. Progress Towards an LES Wall Model Including Unresolved Roughness

    Science.gov (United States)

    Craft, Kyle; Redman, Andrew; Aikens, Kurt

    2015-11-01

    Wall models used in large eddy simulations (LES) are often based on theories for hydraulically smooth walls. While this is reasonable for many applications, there are also many where the impact of surface roughness is important. A previously developed wall model has been used primarily for jet engine aeroacoustics. However, jet simulations have not accurately captured thick initial shear layers found in some experimental data. This may partly be due to nozzle wall roughness used in the experiments to promote turbulent boundary layers. As a result, the wall model is extended to include the effects of unresolved wall roughness through appropriate alterations to the log-law. The methodology is tested for incompressible flat plate boundary layers with different surface roughness. Correct trends are noted for the impact of surface roughness on the velocity profile. However, velocity deficit profiles and the Reynolds stresses do not collapse as well as expected. Possible reasons for the discrepancies as well as future work will be presented. This work used the Extreme Science and Engineering Discovery Environment (XSEDE), which is supported by National Science Foundation grant number ACI-1053575. Computational resources on TACC Stampede were provided under XSEDE allocation ENG150001.

  12. Dynamics of magnetosphere-ionosphere coupling including turbulent transport

    Science.gov (United States)

    Lysak, R. L.; Dum, C. T.

    1983-01-01

    The dynamics of magnetosphere-ionosphere coupling has been investigated by means of a two-dimensional two-fluid MHD model including anomalous resistivity. When field-aligned current is generated on auroral field lines, the disturbance propagates toward the ionosphere in the form of a kinetic Alfven wave. When the current exceeds a critical value, microscopic turbulence is produced, which modifies the propagation of the Alfven wave. This process is modeled by a nonlinear collision frequency, which increases with the excess of the drift velocity over the critical value. The system evolves toward an electrostatic structure, with the perpendicular electric field having a shorter scale than the field-aligned current. The approach to a steady state is strongly dependent on the presence or absence of the turbulence and on the boundary conditions imposed in the generator. As current is increased or scale size is decreased, the turbulent region reflects and absorbs most of the Alfven wave energy, decoupling the generator from the ionosphere.

  13. Radiation and nuclear safety included in the environmental health programme

    International Nuclear Information System (INIS)

    Finland is currently preparing a national environmental health programme, the objective of which is to chart the main environmental health problems in Finland, to identify means for securing a healthy environment, and to draw up a practical action programme for preventing and rectifying problems pertaining to environmental health. Radiation and nuclear safety form an essential part of preventive health care. The action programme is based on decisions and programmes approved at the WHO Conference on the Environment and Health, held in Helsinki in June 1994. In addition to the state of the Finnish environment and the health of the Finnish population, the programme addresses the relevant international issues, in particular in areas adjacent to Finland. The Committee on Environmental Health is expected to complete its work by the end of the year. A wide range of representatives from various branches of administration have contributed to the preparation of the programme. Besides physical, biological and chemical factors, the environmental factors affecting health also include the physical environment and the psychological, social and aesthetic features of the environment. Similarly, environmental factors that have an impact on the health of present or future generations, on the essential preconditions of life and on the quality of life are investigated. The serious risk to nature caused by human actions is also considered as a potential risk to human health. (orig.)

  14. Understanding type 2 diabetes: including the family member's perspective.

    LENUS (Irish Health Repository)

    White, Patricia

    2012-02-01

    PURPOSE: The purpose of this study was to examine the relationship between psychological and social factors and diabetes outcomes in people with type 2 diabetes and their family members. METHODS: A total of 153 patients with type 2 diabetes were assessed at a diabetes outpatient clinic and postal questionnaires were sent to nominated family members. The measures examined were diabetes knowledge, social support, well-being, and illness perceptions. RESULTS: When compared with those with diabetes, family members reported lower positive well-being and lower levels of satisfaction with support. They also perceived diabetes as a more cyclical illness, which was controlled more by treatment than by the individual. Family members also reported that the person with diabetes was more emotionally distressed and knew more about diabetes than the patient had actually reported himself or herself. There were no differences between the family members of those in good or poor glycaemic control. CONCLUSIONS: This study reinforces the importance of understanding social context and illness beliefs in diabetes management. It also highlights the potential for including family members in discussions and education about diabetes management.

  15. Advanced methodology for generation expansion planning including interconnected systems

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, M.; Yokoyama, R.; Yasuda, K. [Tokyo Metropolitan Univ. (Japan); Sasaki, H. [Hiroshima Univ. (Japan); Ogimoto, K. [Electric Power Development Co. Ltd., Tokyo (Japan)

    1994-12-31

    This paper reviews advanced methodology for generation expansion planning including interconnected systems developed in Japan, putting focus on flexibility and efficiency in a practical application. First, criteria for evaluating flexibility of generation planning considering uncertainties are introduced. Secondly, the flexible generation mix problem is formulated as a multi-objective optimization with more than two objective functions. The multi-objective optimization problem is then transformed into a single objective problem by using the weighting method, to obtain the Pareto optimal solution, and solved by a dynamics programming technique. Thirdly, a new approach for electric generation expansion planning of interconnected systems is presented, based on the Benders Decomposition technique. That is, large scale generation problem constituted by the general economic load dispatch problem, and several sub problems which are composed of smaller scale isolated system generation expansion plans. Finally, the generation expansion plan solved by an artificial neural network is presented. In conclusion, the advantages and disadvantages of this method from the viewpoint of flexibility and applicability to practical generation expansion planning are presented. (author) 29 refs., 10 figs., 4 tabs.

  16. Improving the Accuracy of Stamping Analyses Including Springback Deformations

    Science.gov (United States)

    Firat, Mehmet; Karadeniz, Erdal; Yenice, Mustafa; Kaya, Mesut

    2013-02-01

    An accurate prediction of sheet metal deformation including springback is one of the main issues in an efficient finite element (FE) simulation in automotive and stamping industries. Considering tooling design for newer class of high-strength steels, in particular, this requirement became an important aspect for springback compensation practices today. The sheet deformation modeling accounting Bauschinger effect is considered to be a key factor affecting the accuracy of FE simulations in this context. In this article, a rate-independent cyclic plasticity model is presented and implemented into LS-Dyna software for an accurate modeling of sheet metal deformation in stamping simulations. The proposed model uses Hill's orthotropic yield surface in the description of yield loci of planar and transversely anisotropic sheets. The strain-hardening behavior is calculated based on an additive backstress form of the nonlinear kinematic hardening rule. The proposed model is applied in stamping simulations of a dual-phase steel automotive part, and comparisons are presented in terms of part strain and thickness distributions calculated with isotropic plasticity and the proposed model. It is observed that both models produce similar plastic strain and thickness distributions; however, there appeared to be considerable differences in computed springback deformations. Part shapes computed with both plasticity models were evaluated with surface scanning of manufactured parts. A comparison of FE computed geometries with manufactured parts proved the improved performance of proposed model over isotropic plasticity for this particular stamping application.

  17. Validation of CFD for containment jet flows including condensation

    International Nuclear Information System (INIS)

    The advanced validation of a CFD code for containment applications requires the investigation of water steam in the different flow types like jets or buoyant plumes. This paper addresses therefore the simulation of two 'HYJET' experiments from the former Battelle Model Containment by CFX. These experiments involve jet releases into the multi-compartment geometry of the test facility accompanied by condensation of steam at walls and in the bulk gas. In both experiments mixtures of helium and steam are injected. Helium is used to simulate hydrogen. One experiment represents a fast jet whereas in the second test a slow helium-steam release is investigated. CFX was earlier extended by bulk and wall condensation models and is able to model all relevant phenomena observed during the experiments. The paper focuses on the simulation of the two experiments employing an identical model set-up. This provides information on how well a wider range of flowing conditions in case of a full containment simulation can be covered. Some aspects related to numerical and modelling uncertainties of CFD calculations are included in the paper by investigating different turbulence models together with the modelling errors of the differencing schemes applied. (authors)

  18. Constraints on Dark Energy Models Including Gamma Ray Bursts

    CERN Document Server

    Li, H; Fan, Z; Dai, Z; Zhang, X; Li, Hong; Su, Meng; Fan, Zuhui; Dai, Zigao; Zhang, Xinmin

    2008-01-01

    In this paper we analyze the constraints on the property of dark energy from cosmological observations. We include 52 long Gamma-Ray Bursts (GRBs) data in our study. Together with SNe Ia Gold sample, WMAP, SDSS and 2dFGRS data, we perform global fitting using Markov Chain Monte Carlo (MCMC) technique. Dark energy perturbations are explicitly considered. We pay particular attention to the time evolution of the equation of state of dark energy parameterized as w_{DE}=w_o+w_a(1-a) with a the scale factor of the universe, emphasizing the complementarity of high redshift GRBs to other cosmological probes. It is found that the constraints on dark energy become stringent by taking into account high redshift GRBs, especially for w_a, which delineates the evolution of dark energy. The best fitting dark energy model has w_0=-1.09 and w_a=0.89. The cosmological constant with w_0=-1 and w_a=0 is well within 2\\sigma range.

  19. Efficient Algorithms for Electrostatic Interactions Including Dielectric Contrasts

    Directory of Open Access Journals (Sweden)

    Christian Holm

    2013-10-01

    Full Text Available Coarse-grained models of soft matter are usually combined with implicit solvent models that take the electrostatic polarizability into account via a dielectric background. In biophysical or nanoscale simulations that include water, this constant can vary greatly within the system. Performing molecular dynamics or other simulations that need to compute exact electrostatic interactions between charges in those systems is computationally demanding. We review here several algorithms developed by us that perform exactly this task. For planar dielectric surfaces in partial periodic boundary conditions, the arising image charges can be either treated with the MMM2D algorithm in a very efficient and accurate way or with the electrostatic layer correction term, which enables the user to use his favorite 3D periodic Coulomb solver. Arbitrarily-shaped interfaces can be dealt with using induced surface charges with the induced charge calculation (ICC* algorithm. Finally, the local electrostatics algorithm, MEMD(Maxwell Equations Molecular Dynamics, even allows one to employ a smoothly varying dielectric constant in the systems. We introduce the concepts of these three algorithms and an extension for the inclusion of boundaries that are to be held fixed at a constant potential (metal conditions. For each method, we present a showcase application to highlight the importance of dielectric interfaces.

  20. Teachers’ Perceptions of Including Children with Autism in a Preschool

    Directory of Open Access Journals (Sweden)

    Nornadia Mohamad Razali

    2013-08-01

    Full Text Available Inclusive education supports the vision of the United Nations (UN in upholding the fundamental rights of children with special needs towards education. In Malaysia, the Persons with Disabilities Act 2008 recognized the rights of children and persons with disabilities in regards to education. However, the implementation of inclusive education for children with autism in Malaysia has been problematic, especially in preschool. Therefore, this study investigated teachers' perceptions of including children with autism in a mainstream preschool. The objectives of this study were: 1 to determine the attitudes of teachers towards inclusive education 2 to identify the knowledge and skills of pre-school teachers regarding inclusive education 3 to identify the barriers and challenges in implementing inclusive education in pre-school 4 to investigate the reasons behind the non-acceptance of preschool teachers on having children with autism in their classes. Data were collected using a structured interview. Three pre-school teachers in Selangor agreed to participate in this study. The interviews were transcribed text verbatim and information was analyzed by identifying relevant themes. The findings showed that the teachers were not prepared to teach children with autism in their class because they did not know the characteristics of children with autism and did not understand the importance of inclusive education. In conclusion, the practice of inclusive education in pre-school is yet to be implemented successfully due to some constraints experienced by teachers and lack of support in the environment.

  1. Regulation of filamentation in the human fungal pathogen Candida tropicalis.

    Science.gov (United States)

    Zhang, Qiuyu; Tao, Li; Guan, Guobo; Yue, Huizhen; Liang, Weihong; Cao, Chengjun; Dai, Yu; Huang, Guanghua

    2016-02-01

    The yeast-filament transition is essential for the virulence of a variety of fungi that are pathogenic to humans. N-acetylglucosamine (GlcNAc) is a potent inducer of filamentation in Candida albicans and thermally dimorphic fungi such as Histoplasma capsulatum and Blastomyces dermatitidis. However, GlcNAc suppresses rather than promotes filamentation in Candida tropicalis, a fungal species that is closely related to C. albicans. Despite the intensive study in C. albicans, the regulatory mechanism of filamentation is poorly understood. In this study, we demonstrate that the cAMP signaling pathway plays a central role in the regulation of filamentation in C. tropicalis. By screening an overexpression library of 156 transcription factors, we have identified approximately 40 regulators of filamentous growth. Although most of the regulators (e.g., Tec1, Gat2, Nrg1, Sfl1, Sfl2 and Ash1) demonstrate a conserved role in the regulation of filamentation, similar to their homologues in C. albicans or Saccharomyces cerevisiae, a number of transcription factors (e.g., Wor1, Bcr1, Stp4, Efh1, Csr1 and Zcf17) play a specific role in C. tropicalis. Our findings indicate that multiple interconnected signaling pathways are involved in the regulation of filamentation in C. tropicalis. These mechanisms have conserved and divergent features among different Candida species. PMID:26466925

  2. Isolation of Aureimonas altamirensis, a Brucella canis-like bacterium, from an edematous canine testicle.

    Science.gov (United States)

    Reilly, Thomas J; Calcutt, Michael J; Wennerdahl, Laura A; Williams, Fred; Evans, Tim J; Ganjam, Irene K; Bowman, Jesse W; Fales, William H

    2014-11-01

    Microbiological and histological analysis of a sample from a swollen testicle of a 2-year-old Border Collie dog revealed a mixed infection of the fungus Blastomyces dermatitidis and the Gram-negative bacterium Aureimonas altamirensis. When subjected to an automated microbial identification system, the latter isolate was provisionally identified as Psychrobacter phenylpyruvicus, but the organism shared several biochemical features with Brucella canis and exhibited agglutination, albeit weakly, with anti-B. canis antiserum. Unequivocal identification of the organism was only achieved by 16S ribosomal RNA gene sequencing, ultimately establishing the identity as A. altamirensis. Since its first description in 2006, this organism has been isolated infrequently from human clinical samples, but, to the authors' knowledge, has not been reported from a veterinary clinical sample. While of unknown clinical significance with respect to the pathology observed for the polymicrobial infection described herein, it highlights the critical importance to unambiguously identify the microbe for diagnostic, epidemiological, infection control, and public health purposes. PMID:25292192

  3. Olkiluoto surface hydrological modelling: Update 2012 including salt transport modelling

    Energy Technology Data Exchange (ETDEWEB)

    Karvonen, T. [WaterHope, Helsinki (Finland)

    2013-11-15

    Posiva Oy is responsible for implementing a final disposal program for spent nuclear fuel of its owners Teollisuuden Voima Oyj and Fortum Power and Heat Oy. The spent nuclear fuel is planned to be disposed at a depth of about 400-450 meters in the crystalline bedrock at the Olkiluoto site. Leakages located at or close to spent fuel repository may give rise to the upconing of deep highly saline groundwater and this is a concern with regard to the performance of the tunnel backfill material after the closure of the tunnels. Therefore a salt transport sub-model was added to the Olkiluoto surface hydrological model (SHYD). The other improvements include update of the particle tracking algorithm and possibility to estimate the influence of open drillholes in a case where overpressure in inflatable packers decreases causing a hydraulic short-circuit between hydrogeological zones HZ19 and HZ20 along the drillhole. Four new hydrogeological zones HZ056, HZ146, BFZ100 and HZ039 were added to the model. In addition, zones HZ20A and HZ20B intersect with each other in the new structure model, which influences salinity upconing caused by leakages in shafts. The aim of the modelling of long-term influence of ONKALO, shafts and repository tunnels provide computational results that can be used to suggest limits for allowed leakages. The model input data included all the existing leakages into ONKALO (35-38 l/min) and shafts in the present day conditions. The influence of shafts was computed using eight different values for total shaft leakage: 5, 11, 20, 30, 40, 50, 60 and 70 l/min. The selection of the leakage criteria for shafts was influenced by the fact that upconing of saline water increases TDS-values close to the repository areas although HZ20B does not intersect any deposition tunnels. The total limit for all leakages was suggested to be 120 l/min. The limit for HZ20 zones was proposed to be 40 l/min: about 5 l/min the present day leakages to access tunnel, 25 l/min from

  4. Olkiluoto surface hydrological modelling: Update 2012 including salt transport modelling

    International Nuclear Information System (INIS)

    Posiva Oy is responsible for implementing a final disposal program for spent nuclear fuel of its owners Teollisuuden Voima Oyj and Fortum Power and Heat Oy. The spent nuclear fuel is planned to be disposed at a depth of about 400-450 meters in the crystalline bedrock at the Olkiluoto site. Leakages located at or close to spent fuel repository may give rise to the upconing of deep highly saline groundwater and this is a concern with regard to the performance of the tunnel backfill material after the closure of the tunnels. Therefore a salt transport sub-model was added to the Olkiluoto surface hydrological model (SHYD). The other improvements include update of the particle tracking algorithm and possibility to estimate the influence of open drillholes in a case where overpressure in inflatable packers decreases causing a hydraulic short-circuit between hydrogeological zones HZ19 and HZ20 along the drillhole. Four new hydrogeological zones HZ056, HZ146, BFZ100 and HZ039 were added to the model. In addition, zones HZ20A and HZ20B intersect with each other in the new structure model, which influences salinity upconing caused by leakages in shafts. The aim of the modelling of long-term influence of ONKALO, shafts and repository tunnels provide computational results that can be used to suggest limits for allowed leakages. The model input data included all the existing leakages into ONKALO (35-38 l/min) and shafts in the present day conditions. The influence of shafts was computed using eight different values for total shaft leakage: 5, 11, 20, 30, 40, 50, 60 and 70 l/min. The selection of the leakage criteria for shafts was influenced by the fact that upconing of saline water increases TDS-values close to the repository areas although HZ20B does not intersect any deposition tunnels. The total limit for all leakages was suggested to be 120 l/min. The limit for HZ20 zones was proposed to be 40 l/min: about 5 l/min the present day leakages to access tunnel, 25 l/min from

  5. Energy loss in a partonic transport model including bremsstrahlung processes

    International Nuclear Information System (INIS)

    A detailed investigation of the energy loss of gluons that traverse a thermal gluonic medium simulated within the perturbative QCD-based transport model BAMPS (a Boltzmann approach to multiparton scatterings) is presented in the first part of this work. For simplicity the medium response is neglected in these calculations. The energy loss from purely elastic interactions is compared with the case where radiative processes are consistently included based on the matrix element by Gunion and Bertsch. From this comparison, gluon multiplication processes gg→ggg are found to be the dominant source of energy loss within the approach employed here. The consequences for the quenching of gluons with high transverse momentum in fully dynamic simulations of Au+Au collisions at the BNL Relativistic Heavy Ion Collider (RHIC) energy of √(s)=200A GeV are discussed in the second major part of this work. The results for central collisions as discussed in a previous publication are revisited, and first results on the nuclear modification factor RAA for noncentral Au+Au collisions are presented. They show a decreased quenching compared to central collisions while retaining the same shape. The investigation of the elliptic flow v2 is extended up to nonthermal transverse momenta of 10 GeV, exhibiting a maximum v2 at roughly 4 to 5 GeV and a subsequent decrease. Finally the sensitivity of the aforementioned results on the specific implementation of the effective modeling of the Landau-Pomeranchuk-Migdal (LPM) effect via a formation-time-based cutoff is explored.

  6. Identification of astrocytoma associated genes including cell surface markers

    International Nuclear Information System (INIS)

    Despite intense effort the treatment options for the invasive astrocytic tumors are still limited to surgery and radiation therapy, with chemotherapy showing little or no increase in survival. The generation of Serial Analysis of Gene Expression (SAGE) profiles is expected to aid in the identification of astrocytoma-associated genes and highly expressed cell surface genes as molecular therapeutic targets. SAGE tag counts can be easily added to public expression databases and quickly disseminated to research efforts worldwide. We generated and analyzed the SAGE transcription profiles of 25 primary grade II, III and IV astrocytomas [1]. These profiles were produced as part of the Cancer Genome Anatomy Project's SAGE Genie [2], and were used in an in silico search for candidate therapeutic targets by comparing astrocytoma to normal brain transcription. Real-time PCR and immunohistochemistry were used for the validation of selected candidate target genes in 2 independent sets of primary tumors. A restricted set of tumor-associated genes was identified for each grade that included genes not previously associated with astrocytomas (e.g. VCAM1, SMOC1, and thymidylate synthetase), with a high percentage of cell surface genes. Two genes with available antibodies, Aquaporin 1 and Topoisomerase 2A, showed protein expression consistent with transcript level predictions. This survey of transcription in malignant and normal brain tissues reveals a small subset of human genes that are activated in malignant astrocytomas. In addition to providing insights into pathway biology, we have revealed and quantified expression for a significant portion of cell surface and extra-cellular astrocytoma genes

  7. Community Assessment Tool for Public Health Emergencies Including Pandemic Influenza

    Energy Technology Data Exchange (ETDEWEB)

    HCTT-CHE

    2011-04-14

    The Community Assessment Tool (CAT) for Public Health Emergencies Including Pandemic Influenza (hereafter referred to as the CAT) was developed as a result of feedback received from several communities. These communities participated in workshops focused on influenza pandemic planning and response. The 2008 through 2011 workshops were sponsored by the Centers for Disease Control and Prevention (CDC). Feedback during those workshops indicated the need for a tool that a community can use to assess its readiness for a disaster—readiness from a total healthcare perspective, not just hospitals, but the whole healthcare system. The CAT intends to do just that—help strengthen existing preparedness plans by allowing the healthcare system and other agencies to work together during an influenza pandemic. It helps reveal each core agency partners' (sectors) capabilities and resources, and highlights cases of the same vendors being used for resource supplies (e.g., personal protective equipment [PPE] and oxygen) by the partners (e.g., public health departments, clinics, or hospitals). The CAT also addresses gaps in the community's capabilities or potential shortages in resources. While the purpose of the CAT is to further prepare the community for an influenza pandemic, its framework is an extension of the traditional all-hazards approach to planning and preparedness. As such, the information gathered by the tool is useful in preparation for most widespread public health emergencies. This tool is primarily intended for use by those involved in healthcare emergency preparedness (e.g., community planners, community disaster preparedness coordinators, 9-1-1 directors, hospital emergency preparedness coordinators). It is divided into sections based on the core agency partners, which may be involved in the community's influenza pandemic influenza response.

  8. Identification of astrocytoma associated genes including cell surface markers

    Directory of Open Access Journals (Sweden)

    Eberhart Charles G

    2004-07-01

    Full Text Available Abstract Background Despite intense effort the treatment options for the invasive astrocytic tumors are still limited to surgery and radiation therapy, with chemotherapy showing little or no increase in survival. The generation of Serial Analysis of Gene Expression (SAGE profiles is expected to aid in the identification of astrocytoma-associated genes and highly expressed cell surface genes as molecular therapeutic targets. SAGE tag counts can be easily added to public expression databases and quickly disseminated to research efforts worldwide. Methods We generated and analyzed the SAGE transcription profiles of 25 primary grade II, III and IV astrocytomas 1. These profiles were produced as part of the Cancer Genome Anatomy Project's SAGE Genie 2, and were used in an in silico search for candidate therapeutic targets by comparing astrocytoma to normal brain transcription. Real-time PCR and immunohistochemistry were used for the validation of selected candidate target genes in 2 independent sets of primary tumors. Results A restricted set of tumor-associated genes was identified for each grade that included genes not previously associated with astrocytomas (e.g. VCAM1, SMOC1, and thymidylate synthetase, with a high percentage of cell surface genes. Two genes with available antibodies, Aquaporin 1 and Topoisomerase 2A, showed protein expression consistent with transcript level predictions. Conclusions This survey of transcription in malignant and normal brain tissues reveals a small subset of human genes that are activated in malignant astrocytomas. In addition to providing insights into pathway biology, we have revealed and quantified expression for a significant portion of cell surface and extra-cellular astrocytoma genes.

  9. Kinetic models of gene expression including non-coding RNAs

    Energy Technology Data Exchange (ETDEWEB)

    Zhdanov, Vladimir P., E-mail: zhdanov@catalysis.r

    2011-03-15

    In cells, genes are transcribed into mRNAs, and the latter are translated into proteins. Due to the feedbacks between these processes, the kinetics of gene expression may be complex even in the simplest genetic networks. The corresponding models have already been reviewed in the literature. A new avenue in this field is related to the recognition that the conventional scenario of gene expression is fully applicable only to prokaryotes whose genomes consist of tightly packed protein-coding sequences. In eukaryotic cells, in contrast, such sequences are relatively rare, and the rest of the genome includes numerous transcript units representing non-coding RNAs (ncRNAs). During the past decade, it has become clear that such RNAs play a crucial role in gene expression and accordingly influence a multitude of cellular processes both in the normal state and during diseases. The numerous biological functions of ncRNAs are based primarily on their abilities to silence genes via pairing with a target mRNA and subsequently preventing its translation or facilitating degradation of the mRNA-ncRNA complex. Many other abilities of ncRNAs have been discovered as well. Our review is focused on the available kinetic models describing the mRNA, ncRNA and protein interplay. In particular, we systematically present the simplest models without kinetic feedbacks, models containing feedbacks and predicting bistability and oscillations in simple genetic networks, and models describing the effect of ncRNAs on complex genetic networks. Mathematically, the presentation is based primarily on temporal mean-field kinetic equations. The stochastic and spatio-temporal effects are also briefly discussed.

  10. Kinetic models of gene expression including non-coding RNAs

    Science.gov (United States)

    Zhdanov, Vladimir P.

    2011-03-01

    In cells, genes are transcribed into mRNAs, and the latter are translated into proteins. Due to the feedbacks between these processes, the kinetics of gene expression may be complex even in the simplest genetic networks. The corresponding models have already been reviewed in the literature. A new avenue in this field is related to the recognition that the conventional scenario of gene expression is fully applicable only to prokaryotes whose genomes consist of tightly packed protein-coding sequences. In eukaryotic cells, in contrast, such sequences are relatively rare, and the rest of the genome includes numerous transcript units representing non-coding RNAs (ncRNAs). During the past decade, it has become clear that such RNAs play a crucial role in gene expression and accordingly influence a multitude of cellular processes both in the normal state and during diseases. The numerous biological functions of ncRNAs are based primarily on their abilities to silence genes via pairing with a target mRNA and subsequently preventing its translation or facilitating degradation of the mRNA-ncRNA complex. Many other abilities of ncRNAs have been discovered as well. Our review is focused on the available kinetic models describing the mRNA, ncRNA and protein interplay. In particular, we systematically present the simplest models without kinetic feedbacks, models containing feedbacks and predicting bistability and oscillations in simple genetic networks, and models describing the effect of ncRNAs on complex genetic networks. Mathematically, the presentation is based primarily on temporal mean-field kinetic equations. The stochastic and spatio-temporal effects are also briefly discussed.

  11. Kinetic models of gene expression including non-coding RNAs

    International Nuclear Information System (INIS)

    In cells, genes are transcribed into mRNAs, and the latter are translated into proteins. Due to the feedbacks between these processes, the kinetics of gene expression may be complex even in the simplest genetic networks. The corresponding models have already been reviewed in the literature. A new avenue in this field is related to the recognition that the conventional scenario of gene expression is fully applicable only to prokaryotes whose genomes consist of tightly packed protein-coding sequences. In eukaryotic cells, in contrast, such sequences are relatively rare, and the rest of the genome includes numerous transcript units representing non-coding RNAs (ncRNAs). During the past decade, it has become clear that such RNAs play a crucial role in gene expression and accordingly influence a multitude of cellular processes both in the normal state and during diseases. The numerous biological functions of ncRNAs are based primarily on their abilities to silence genes via pairing with a target mRNA and subsequently preventing its translation or facilitating degradation of the mRNA-ncRNA complex. Many other abilities of ncRNAs have been discovered as well. Our review is focused on the available kinetic models describing the mRNA, ncRNA and protein interplay. In particular, we systematically present the simplest models without kinetic feedbacks, models containing feedbacks and predicting bistability and oscillations in simple genetic networks, and models describing the effect of ncRNAs on complex genetic networks. Mathematically, the presentation is based primarily on temporal mean-field kinetic equations. The stochastic and spatio-temporal effects are also briefly discussed.

  12. Do pigeons prefer alternatives that include near-hit outcomes?

    Science.gov (United States)

    Stagner, Jessica P; Case, Jacob P; Sticklen, Mary F; Duncan, Amanda K; Zentall, Thomas R

    2015-07-01

    Pigeons show suboptimal choice on a gambling-like task similar to that shown by humans. Humans also show a preference for gambles in which there are near hits (losses that come close to winning). In the present research, we asked if pigeons would show a preference for alternatives with near-hit-like trials. In Experiment 1, we included an alternative that presented a near hit, in which a stimulus associated with reinforcement (a presumed conditioned reinforcer) changed to a stimulus associated with the absence of reinforcement (a presumed conditioned inhibitor). The pigeons tended to avoid this alternative. In Experiment 2, we varied the duration of the presumed conditioned reinforcer (2 vs. 8 s) that changed to a presumed conditioned inhibitor (8 vs. 2 s) and found that the longer the conditioned reinforcer was presented, the more the pigeons avoided it. In Experiment 3, the near-hit alternative involved an ambiguous stimulus for 8 s that changed to a presumed conditioned reinforcer (or a presumed conditioned inhibitor) for 2 s, but the pigeons still avoided it. In Experiment 4, we controlled for the duration of the conditioned reinforcer by presenting it first for 2 s followed by the ambiguous stimulus for 8 s. Once again, the pigeons avoided the alternative with the near-hit trials. In all 4 experiments, the pigeons tended to avoid alternatives that provided near-hit-like trials. We concluded that humans may be attracted to near-hit trials because near-hit trials give them the illusion of control, whereas this does not appear to be a factor for pigeons. PMID:26167775

  13. Deformable registration of multi-modal data including rigid structures

    International Nuclear Information System (INIS)

    Multi-modality imaging studies are becoming more widely utilized in the analysis of medical data. Anatomical data from CT and MRI are useful for analyzing or further processing functional data from techniques such as PET and SPECT. When data are not acquired simultaneously, even when these data are acquired on a dual-imaging device using the same bed, motion can occur that requires registration between the reconstructed image volumes. As the human torso can allow non-rigid motion, this type of motion should be estimated and corrected. We report a deformation registration technique that utilizes rigid registration for bony structures, while allowing elastic transformation of soft tissue to more accurately register the entire image volume. The technique is applied to the registration of CT and MR images of the lumbar spine. First a global rigid registration is performed to approximately align features. Bony structures are then segmented from the CT data using semi-automated process, and bounding boxes for each vertebra are established. Each CT subvolume is then individually registered to the MRI data using a piece-wise rigid registration algorithm and a mutual information image similarity measure. The resulting set of rigid transformations allows for accurate registration of the parts of the CT and MRI data representing the vertebrae, but not the adjacent soft tissue. To align the soft tissue, a smoothly-varying deformation is computed using a thin platespline(TPS) algorithm. The TPS technique requires a sparse set of landmarks that are to be brought into correspondence. These landmarks are automatically obtained from the segmented data using simple edge-detection techniques and random sampling from the edge candidates. A smoothness parameter is also included in the TPS formulation for characterization of the stiffness of the soft tissue. Estimation of an appropriate stiffness factor is obtained iteratively by using the mutual information cost function on the result

  14. Three-dimensional inversion of CSAMT data including topography

    Science.gov (United States)

    Lin, C.; Tan, H.; Tong, T.; Zeng, W.

    2013-12-01

    CSAMT is widely used in geothermal prospecting, mineral and petroleum exploration, environmental geophysics and geological engineering. However, few data are collected on the flat surface in the field CSAMT work. Most of CSAMT data are collected in the presence of strong topography either at the source position or in the survey area. Large interpretation errors may occur in CSAMT surveys if field distortions caused by the surface topography are not considered. Therefore, the CSAMT inversion should consider the topographic effect. In this work we develop a 3D inversion algorithm for inverting CSAMT data with topography using conjugate gradient inversion method. In the 3D forward problem, the total electric and magnetic fields is separated into their primary and secondary components to calculate the response from the 3D model with irregular topography. 3D rectangular grid with stair-stepped ground-air interface is used to approximate topography. The primary electric and magnetic field can be calculated by one-dimensional modeling, using the altitude of the highest point of the topography as the altitude of the flat surface. The secondary electric and magnetic field can be calculated using the staggered-grid finite difference method. Then, the apparent resistivity and phase response can be obtained by Cagniard equation. In the 3D inversion problem, conjugate gradient method is used to invert the CSAMT apparent resistivity and phase data including topography. The background resistivity is a constant value and the anomalous resistivity is used as the inversion parameter. Only the anomalous resistivity under the surface topography is updated in the inversion. Results from the synthetic tests show the validity and stability of the inversion algorithm.

  15. Monitoring of tritium-contaminated surfaces, including skin

    International Nuclear Information System (INIS)

    We have examined various commercially available tritium surface contamination monitors along with different swipe media and techniques for direct and indirect (swipe) monitoring of contaminated surfaces, including skin. None of the methods or instruments evaluated were more sensitive than the swipe and liquid scintillation counting (LSC) method. Swipe measurements with open-window proportional counters were, in general, less than half as sensitive as LSC, but have the advantages of having the results available almost immediately, and no sample preparation is required. The Nuclear Measurement Corporation's PC-55 is the most suitable instrument we tested for the analysis of routine swipe measurement. The PC-55 was about one third as sensitive as LSC when used with Ontario Hydro filter paper swipe media. Surface contamination measurement results can be obtained within minutes using the PC-55, compared to hours using LSC. The selection of swipe media for use with proportional counter-based instruments is critical. A medium that is electrically insulating can develop an electrostatic charge on its surface; this may alter the field gradient in the detector and may adversely influence the results. Although the PC-55 is sufficiently sensitive and very convenient, operational experience with the instrument is needed before recommending that it replace current LSC methods. The PC-55's susceptibility to internal tritium contamination may limit its practical usefulness. Because of the complexity of using live animals to evaluate direct and indirect methods for assessing skin contamination, pig skin was investigated as a possible substitute. We concluded that, for the first few hours post-exposure, pig skin mimics the kinetics of animal skin that has contacted a tritium-contaminated surface. (author). 30 refs., 1 tab., 7 figs

  16. Deformable registration of multi-modal data including rigid structures

    Energy Technology Data Exchange (ETDEWEB)

    Huesman, Ronald H.; Klein, Gregory J.; Kimdon, Joey A.; Kuo, Chaincy; Majumdar, Sharmila

    2003-05-02

    Multi-modality imaging studies are becoming more widely utilized in the analysis of medical data. Anatomical data from CT and MRI are useful for analyzing or further processing functional data from techniques such as PET and SPECT. When data are not acquired simultaneously, even when these data are acquired on a dual-imaging device using the same bed, motion can occur that requires registration between the reconstructed image volumes. As the human torso can allow non-rigid motion, this type of motion should be estimated and corrected. We report a deformation registration technique that utilizes rigid registration for bony structures, while allowing elastic transformation of soft tissue to more accurately register the entire image volume. The technique is applied to the registration of CT and MR images of the lumbar spine. First a global rigid registration is performed to approximately align features. Bony structures are then segmented from the CT data using semi-automated process, and bounding boxes for each vertebra are established. Each CT subvolume is then individually registered to the MRI data using a piece-wise rigid registration algorithm and a mutual information image similarity measure. The resulting set of rigid transformations allows for accurate registration of the parts of the CT and MRI data representing the vertebrae, but not the adjacent soft tissue. To align the soft tissue, a smoothly-varying deformation is computed using a thin platespline(TPS) algorithm. The TPS technique requires a sparse set of landmarks that are to be brought into correspondence. These landmarks are automatically obtained from the segmented data using simple edge-detection techniques and random sampling from the edge candidates. A smoothness parameter is also included in the TPS formulation for characterization of the stiffness of the soft tissue. Estimation of an appropriate stiffness factor is obtained iteratively by using the mutual information cost function on the result

  17. How Might Industry Governance Be Broadened To Include Nonproliferation

    International Nuclear Information System (INIS)

    Broadening industry governance to support nonproliferation could provide significant new leverage in preventing the spread/diversion of nuclear, radiological, or dual-use material or technology that could be used in making a nuclear or radiological weapon. Industry is defined broadly to include (1) the nuclear industry, (2) dual-use industries, and (3) radioactive source manufacturers and selected radioactive source-user industries worldwide. This paper describes how industry can be an important first line of defense in detecting and thwarting proliferation, such as an illicit trade network or an insider theft case, by complementing and strengthening existing governmental efforts. For example, the dual-use industry can play a critical role by providing export, import, or security control information that would allow a government or the International Atomic Energy Agency (IAEA) to integrate this information with safeguards, export, import, and physical protection information it has to create a more complete picture of the potential for proliferation. Because industry is closest to users of the goods and technology that could be illicitly diverted throughout the supply chain, industry information can potentially be more timely and accurate than other sources of information. Industry is in an ideal position to help ensure that such illicit activities are detected. This role could be performed more effectively if companies worked together within a particular industry to promote nonproliferation by implementing an industry-wide self-regulation program. Performance measures could be used to ensure their materials and technologies are secure throughout the supply chain and that customers are legitimately using and/or maintaining oversight of these items. Nonproliferation is the overarching driver that industry needs to consider in adopting and implementing a self-regulation approach. A few foreign companies have begun such an approach to date; it is believed that

  18. Including collisions in gyrokinetic tokamak and stellarator simulations

    Energy Technology Data Exchange (ETDEWEB)

    Kauffmann, Karla

    2012-04-10

    ITGs and TEMs in a tokamak configuration. The results show that collisions reduce the growth rate of slab ITGs in cylinder geometry, whereas they do not affect ITGs in a tokamak, which are mainly curvature-driven. However it is important to note that the pitch-angle scattering operator does not conserve momentum, which is most critical in the parallel direction. Therefore, the damping found in a cylinder could be the consequence of this missing feature and not a physical result [Dimits and Cohen 1994]. Nonetheless, the results are useful to determine whether the instability is mainly being driven by a slab or toroidal ITG mode. EUTERPE also has the feature of including kinetic electrons, which made simulations of TEMs with collisions possible. The combination of collisions and kinetic electrons made the numerical calculations extremely time-consuming, since the time step had to be small enough to resolve the fast electron motion. In contrast to the ITG results, it was observed that collisions are extremely important for TEMs in a tokamak, and in some special cases, depending on whether they were mainly driven by density or temperature gradients, collisions could even suppress the mode (in agreement with [Angioni et al. 2005, Connor et al. 2006]). In the case of stellarators it was found that ITGs are highly dependent on the device configuration. For LHD it was shown that collisions slightly reduce the growth rate of the instability, but for Wendelstein 7-X they do not affect it and the growth rate showed a similar trend with collisionality to that of the tokamak case. Collisions also tend to make the ballooning structure of the modes less pronounced.

  19. Should LSP Dictionaries. also Include Professional Jargon and Slang?

    Directory of Open Access Journals (Sweden)

    Rosemarie Gläser

    2011-10-01

    Full Text Available

    Abstract: The paper discusses the question whether an LSP dictionary should take the sociolinguistic stratification of the entire speech community in a particular domain of activity into consideration, and as a consequence, also encompass vocabulary on the lower stylistic levels, such as professional jargon and occupational slang in addition to technical terminology and nomenclature. The author's contention is that by including such vocabulary, an LSP dictionary will be more comprehensive and closer to the communicative reality. Moreover. it will meet the more specific requirements of translators and interpreters. To substantiate this claim, the author examined two monolingual English dictionaries and five bilingual English-German (German-English dictionaries published between 1973 and 2000, which have successfully incorporated professional jargon and slang. The subject areas covered range from law, economics, accountancy and business administration to geology, geophysics, geotectonics, and to automotive engineering. Some lexicographers have used style markers or usage labels (such as informal, colloquial, slang, vulgar, umgangssprach/ ich, fdrmlich, gelwben, finance, motoring, press for vocabulary bearing stylistic or expressive connotations. As a rule, these style markers have only been given to key words of the source language so that they may be inferred for the target language equivalent. Ideally, as one dictionary author has proved, style markers should also be attached to target language equivalents. However, an LSP lexicographer must be aware of the fact that informal and slang words may be short-lived and be substituted by other colloquial and colourful words from oral communication - and that slang words may gradually lose their connotations and become stylistically neutral words and even terms.

    Keywords: LSP DICTIONARY, TECHNICAL TERM, ITEM OF NOMENCLATURE, TRIVIAL (POPULAR NAME, PROFESSIONAL JARGON, OCCUPATIONAL SLANG, TRADE

  20. Technical aspects of innovative nuclear systems including reliability and safety

    International Nuclear Information System (INIS)

    more cost-effective. The 'User' in the IAEA terminology is a wide range meaning. It includes investors, designers/engineers, Utilities, Regulatory Bodies, and Consumers of nuclear power industry useful products. Therefore, there are some contradictions within this society. The Licensing Authorities play specific role as spokesman of community common requirements. Therefore they might become a key persons in search of optimum relationship among all requirements and criteria. 6. The representatives of Licensing Authorities together with Designers, Engineering Organizations, Manufacturers, Economists and Ecologists should participate in discussions of innovative technology proposals just at the earliest possible stages. It will allow them to make their recommendations at the benefit of those technologies that are worth to be further developed. It is assumed expedient to discuss two topics, namely: International co-operation of Licensing Authorities that might facilitate improvement of 'licensing infrastructure' and licensing activity at international level and; Producing of mutually acceptable fundamental principles and approaches as well as, probably, unified standards to be applied to innovative technologies at the international level. The representatives of developing countries - upon the forecast, they will be the main consumers of nuclear technologies of the current century - would become the direct participants of such a co-operation. 7. Careful study of proposals on future nuclear technologies shows that they are allocated, mainly, in the frame of already well known and investigated systems. While having the advantage of high reliability of evaluations, such Projects have predetermined limits of improvement of economical performances and safety. Such Projects could not allow to find a solution for the contradiction that is: to make the new nuclear technology much more safe and, at the same time, more economically competitive rather than the conventional power

  1. 78 FR 1247 - Certain Electronic Devices, Including Wireless Communication Devices, Tablet Computers, Media...

    Science.gov (United States)

    2013-01-08

    ... COMMISSION Certain Electronic Devices, Including Wireless Communication Devices, Tablet Computers, Media... United States after importation of certain electronic devices, including wireless communication devices... importation of certain electronic devices, including wireless communication devices, tablet computers,...

  2. 77 FR 18860 - Certain Consumer Electronics, Including Mobile Phones and Tablets; Notice of Receipt of Complaint...

    Science.gov (United States)

    2012-03-28

    ... COMMISSION Certain Consumer Electronics, Including Mobile Phones and Tablets; Notice of Receipt of Complaint... complaint entitled Certain Consumer Electronics, Including Mobile Phones and Tablets, DN 2885; the... importation of certain consumer electronics, including mobile phones and tablets. The complaint names...

  3. Composite materials and bodies including silicon carbide and titanium diboride and methods of forming same

    Science.gov (United States)

    Lillo, Thomas M.; Chu, Henry S.; Harrison, William M.; Bailey, Derek

    2013-01-22

    Methods of forming composite materials include coating particles of titanium dioxide with a substance including boron (e.g., boron carbide) and a substance including carbon, and reacting the titanium dioxide with the substance including boron and the substance including carbon to form titanium diboride. The methods may be used to form ceramic composite bodies and materials, such as, for example, a ceramic composite body or material including silicon carbide and titanium diboride. Such bodies and materials may be used as armor bodies and armor materials. Such methods may include forming a green body and sintering the green body to a desirable final density. Green bodies formed in accordance with such methods may include particles comprising titanium dioxide and a coating at least partially covering exterior surfaces thereof, the coating comprising a substance including boron (e.g., boron carbide) and a substance including carbon.

  4. Momentum relation and classical limit in the future-not-included complex action theory

    CERN Document Server

    Nagao, Keiichi

    2013-01-01

    Studying the time development of the expectation value in the future-not-included complex action theory we point out that the momentum relation (relation analogous to $p=\\frac{\\partial L}{\\partial \\dot{q}}$), which was derived via Feynman path integral and was shown to be right in the future-included theory in our previous papers, is not valid in the future-not-included theory. We provide the correct momentum relation in the future-not-included theory, and argue that the future-not-included classical theory is described by a certain real action. In addition we provide another way to understand the time development of the future-not-included theory by utilizing the future-included theory. Furthermore, applying the method used in our previous paper to the future-not-included theory properly by introducing a formal Lagrangian, we derive the correct momentum relation in the future-not-included theory.

  5. 76 FR 36154 - In the Matter of Certain Equipment for Communications Networks, Including Switches, Routers...

    Science.gov (United States)

    2011-06-21

    ... COMMISSION In the Matter of Certain Equipment for Communications Networks, Including Switches, Routers... United States after importation of certain equipment for communications networks, including switches... importation, or the sale within the United States after importation of certain equipment for...

  6. 76 FR 41525 - Hewlett Packard Global Parts Supply Chain, Global Product Life Cycles Management Unit Including...

    Science.gov (United States)

    2011-07-14

    ... Parts Supply Chain, Global Product Life Cycles Management Unit, including teleworkers reporting to... Chain, Global Product Life Cycles Management Unit, including teleworkers reporting to Houston, Texas... Employment and Training Administration Hewlett Packard Global Parts Supply Chain, Global Product Life...

  7. 78 FR 38361 - Certain Portable Electronic Communications Devices, Including Mobile Phones and Components...

    Science.gov (United States)

    2013-06-26

    ... COMMISSION Certain Portable Electronic Communications Devices, Including Mobile Phones and Components Thereof... States after importation of certain portable electronic ] communications devices, including mobile phones... information concerning the Commission may also be obtained by accessing its internet server at...

  8. Geologic provinces of Europe including Turkey, 2000 (prv4_2l)

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This coverage includes arcs, polygons and polygon labels that describe U.S. Geological Survey defined geologic provinces of Europe including Turkey. (Albania,...

  9. 77 FR 70464 - Certain Electronic Devices, Including Wireless Communication Devices, Portable Music and Data...

    Science.gov (United States)

    2012-11-26

    ... COMMISSION Certain Electronic Devices, Including Wireless Communication Devices, Portable Music and Data... Telecommunications America, LLC of Richardson, Texas (collectively, ``Samsung''). 76 FR 45860 (Aug. 1, 2011). The... importation of certain electronic devices, including wireless communication devices, portable music and...

  10. 77 FR 60720 - Certain Electronic Devices, Including Wireless Commmunication Devices, Portable Music and Data...

    Science.gov (United States)

    2012-10-04

    ... From the Federal Register Online via the Government Publishing Office INTERNATIONAL TRADE COMMISSION Certain Electronic Devices, Including Wireless Commmunication Devices, Portable Music and Data... infringing electronic devices, including wireless communication devices, portable music and data...

  11. 78 FR 16865 - Certain Electronic Devices, Including Wireless Communication Devices, Portable Music and Data...

    Science.gov (United States)

    2013-03-19

    ... COMMISSION Certain Electronic Devices, Including Wireless Communication Devices, Portable Music and Data... America, LLC of Richardson, Texas (collectively, ``Samsung''). 76 FR 45860 (Aug. 1, 2011). The complaint... importation of certain electronic devices, including wireless communication devices, portable music and...

  12. Generalized Geology of Europe including Turkey (geo4_2l)

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This coverage includes arcs, polygons, and polygon labels that describe the generalized geologic age of surface outcrops of bedrock of Europe including Turkey...

  13. 17 CFR 232.104 - Unofficial PDF copies included in an electronic submission.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Unofficial PDF copies included... Filing Requirements § 232.104 Unofficial PDF copies included in an electronic submission. (a) An... (§ 249.101 of this chapter) or a Form D (§ 239.500 of this chapter), may include one unofficial PDF...

  14. 45 CFR 233.53 - Support and maintenance assistance (including home energy assistance) in AFDC.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Support and maintenance assistance (including home... § 233.53 Support and maintenance assistance (including home energy assistance) in AFDC. (a) General. At State option, certain support and maintenance assistance (including home energy assistance) may...

  15. 12 CFR 516.55 - What information must I include in my public notice?

    Science.gov (United States)

    2010-01-01

    ... APPLICATION PROCESSING PROCEDURES Publication Requirements § 516.55 What information must I include in my public notice? Your public notice must include the following: (a) Your name and address. (b) The type of... 12 Banks and Banking 5 2010-01-01 2010-01-01 false What information must I include in my...

  16. 7 CFR 1755.98 - List of telecommunications specifications included in other 7 CFR parts.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false List of telecommunications specifications included in other 7 CFR parts. 1755.98 Section 1755.98 Agriculture Regulations of the Department of Agriculture... included in other 7 CFR parts. The following specifications are included throughout 7 CFR chapter...

  17. 20 CFR 416.929 - How we evaluate symptoms, including pain.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false How we evaluate symptoms, including pain. 416....929 How we evaluate symptoms, including pain. (a) General. In determining whether you are disabled, we consider all your symptoms, including pain, and the extent to which your symptoms can reasonably...

  18. 20 CFR 404.1529 - How we evaluate symptoms, including pain.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false How we evaluate symptoms, including pain. 404... evaluate symptoms, including pain. (a) General. In determining whether you are disabled, we consider all your symptoms, including pain, and the extent to which your symptoms can reasonably be accepted...

  19. 21 CFR 111.260 - What must the batch record include?

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What must the batch record include? 111.260... for the Batch Production Record § 111.260 What must the batch record include? The batch production record must include the following: (a) The batch, lot, or control number: (1) Of the finished batch...

  20. 15 CFR 754.3 - Petroleum products not including crude oil.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Petroleum products not including crude... SUPPLY CONTROLS § 754.3 Petroleum products not including crude oil. (a) License requirement. As indicated... required to all destinations, including Canada, for the export of petroleum products, excluding crude...

  1. 30 CFR 250.110 - What must I include in my welding plan?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What must I include in my welding plan? 250.110... must I include in my welding plan? You must include all of the following in the Welding Plan that you... qualified personnel weld; (c) Practices and procedures for safe welding that address: (1) Welding...

  2. A conserved dimorphism-regulating histidine kinase controls the dimorphic switching in Paracoccidioides brasiliensis.

    Science.gov (United States)

    Chaves, Alison F A; Navarro, Marina V; Castilho, Daniele G; Calado, Juliana C P; Conceição, Palloma M; Batista, Wagner L

    2016-08-01

    Paracoccidioides brasiliensis and P. lutzii, thermally dimorphic fungi, are the causative agents of paracoccidioidomycosis (PCM). Paracoccidioides infection occurs when conidia or mycelium fragments are inhaled by the host, which causes the Paracoccidioides cells to transition to the yeast form. The development of disease requires conidia inside the host alveoli to differentiate into yeast cells in a temperature-dependent manner. We describe the presence of a two-component signal transduction system in P. brasiliensis, which we investigated by expression analysis of a hypothetical protein gene (PADG_07579) that showed high similarity with the dimorphism-regulating histidine kinase (DRK1) gene of Blastomyces dermatitidis and Histoplasma capsulatum This gene was sensitive to environmental redox changes, which was demonstrated by a dose-dependent decrease in transcript levels after peroxide stimulation and a subtler decrease in transcript levels after NO stimulation. Furthermore, the higher PbDRK1 levels after treatment with increasing NaCl concentrations suggest that this histidine kinase can play a role as osmosensing. In the mycelium-yeast (M→Y) transition, PbDRK1 mRNA expression increased 14-fold after 24 h incubation at 37°C, consistent with similar observations in other virulent fungi. These results demonstrate that the PbDRK1 gene is differentially expressed during the dimorphic M→Y transition. Finally, when P. brasiliensis mycelium cells were exposed to a histidine kinase inhibitor and incubated at 37°C, there was a delay in the dimorphic M→Y transition, suggesting that histidine kinases could be targets of interest for PCM therapy. PMID:27268997

  3. Tc17 cells mediate vaccine immunity against lethal fungal pneumonia in immune deficient hosts lacking CD4+ T cells.

    Directory of Open Access Journals (Sweden)

    Som Gowda Nanjappa

    Full Text Available Vaccines may help reduce the growing incidence of fungal infections in immune-suppressed patients. We have found that, even in the absence of CD4(+ T-cell help, vaccine-induced CD8(+ T cells persist and confer resistance against Blastomyces dermatitidis and Histoplasma capsulatum. Type 1 cytokines contribute to that resistance, but they also are dispensable. Although the role of T helper 17 cells in immunity to fungi is debated, IL-17 producing CD8(+ T cells (Tc17 cells have not been investigated. Here, we show that Tc17 cells are indispensable in antifungal vaccine immunity in hosts lacking CD4(+ T cells. Tc17 cells are induced upon vaccination, recruited to the lung on pulmonary infection, and act non-redundantly in mediating protection in a manner that requires neutrophils. Tc17 cells did not influence type I immunity, nor did the lack of IL-12 signaling augment Tc17 cells, indicating a distinct lineage and function. IL-6 was required for Tc17 differentiation and immunity, but IL-1R1 and Dectin-1 signaling was unexpectedly dispensable. Tc17 cells expressed surface CXCR3 and CCR6, but only the latter was essential in recruitment to the lung. Although IL-17 producing T cells are believed to be short-lived, effector Tc17 cells expressed low levels of KLRG1 and high levels of the transcription factor TCF-1, predicting their long-term survival and stem-cell like behavior. Our work has implications for designing vaccines against fungal infections in immune suppressed patients.

  4. The involuntary excluder effect: those included by an excluder are seen as exclusive themselves.

    Science.gov (United States)

    Critcher, Clayton R; Zayas, Vivian

    2014-09-01

    People are highly vigilant for and alarmed by social exclusion. Previous research has focused largely on the emotional and motivational consequences of being unambiguously excluded by others. The present research instead examines how people make sense of a more ambiguous dynamic, 1-person exclusion--situations in which one person (the excluder) excludes someone (the rejected) while including someone else (the included). Using different methodological paradigms, converging outcome measures, and complementary comparison standards, 5 studies present evidence of an involuntary excluder effect: Social perceivers are quick to see included persons as though they are excluders themselves. Included individuals are seen as belonging to an exclusive alliance with the excluder, as liking the excluder more than the rejected, and as likely to perpetuate future exclusion against the rejected. Behavioral evidence reinforced these findings: The included was approached with caution and suspicion. Notably, such perceptions of the included as an excluder were drawn by the rejected themselves and outside observers alike, did not reflect the attitudes and intentions of included persons or those who simulated 1-person exclusion from the vantage point of the included, applied specifically to the included (but not someone who simply witnessed the rejected's rejection), and arose as a consequence of intentional acts of exclusion (and thus, not just because 2 individuals shared an exclusive experience). Consistencies with and contributions to literatures on balance theory, minimal groups, group entitativity, and the ostracism detection system literatures are discussed. PMID:25133726

  5. 75 FR 26793 - Fypon, Ltd., Parkersburg, WV, Including Workers Whose Unemployment Insurance, (UI) Wages Are Paid...

    Science.gov (United States)

    2010-05-12

    ... Federal Register on March 5, 2010 (75 FR 10321). At the request of the state, the Department reviewed the... Employment and Training Administration Fypon, Ltd., Parkersburg, WV, Including Workers Whose Unemployment... Leased Workers From Job1 USA, Including Workers Whose Unemployment Insurance, (UI) Wages Are Paid...

  6. 25 CFR 30.115 - Which students' performance data must be included for purposes of AYP?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Which students' performance data must be included for... EDUCATION ADEQUATE YEARLY PROGRESS Assessing Adequate Yearly Progress § 30.115 Which students' performance data must be included for purposes of AYP? The performance data of all students assessed pursuant...

  7. 49 CFR 174.204 - Tank car delivery of gases, including cryogenic liquids.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Tank car delivery of gases, including cryogenic... CARRIAGE BY RAIL Detailed Requirements for Class 2 (Gases) Materials § 174.204 Tank car delivery of gases, including cryogenic liquids. (a) A tank car containing Class 2 (gases) material may not be unloaded...

  8. 42 CFR 493.941 - Hematology (including routine hematology and coagulation).

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Hematology (including routine hematology and....941 Hematology (including routine hematology and coagulation). (a) Program content and frequency of challenge. To be approved for proficiency testing for hematology, a program must provide a minimum of...

  9. 77 FR 21996 - Certain Equipment for Communications Networks, Including Switches, Routers, Gateways, Bridges...

    Science.gov (United States)

    2012-04-12

    ... COMMISSION Certain Equipment for Communications Networks, Including Switches, Routers, Gateways, Bridges... States after importation of certain equipment for communications networks, including switches, routers...,633,966; and 5,841,360. 76 FR 36154-55 (June 21, 2011). The Notice of Investigation named...

  10. Cascade Controller Including Back-stepping for Hydraulic-Mechanical Systems

    DEFF Research Database (Denmark)

    Choux, Martin; Hovland, Geir; Blanke, Mogens

    Development of a cascade controller structure including adaptive backstepping for a nonlinear hydraulic-mechanical system is considered in this paper where a dynamic friction (LuGre) model is included to obtain the necessary accuracy. The paper compares the performance of two variants of an...

  11. 12 CFR 563b.105 - What information must I include in my business plan?

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false What information must I include in my business plan? 563b.105 Section 563b.105 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE... expectations, and industry norms, by the final year of the business plan. You must include three years...

  12. 75 FR 20860 - Certain Display Devices, Including Digital Televisions and Monitors; Notice of Investigation

    Science.gov (United States)

    2010-04-21

    ... COMMISSION Certain Display Devices, Including Digital Televisions and Monitors; Notice of Investigation... devices, including digital televisions and monitors by reason of infringement of certain claims of U.S... terminal on 202-205-1810. Persons with mobility impairments who will need special assistance in...

  13. Least-Squares Camera Calibration Including Lens Distortion and Automatic Editing of Calibration Points

    Science.gov (United States)

    Gennery, D. B.

    1998-01-01

    A method is described for calibrating cameras including radial lens distortion, by using known points such as those measured from a calibration fixture. The distortion terms are relative to the optical axis, which is included in the model so that it does not have to be orthogonal to the image sensor plane.

  14. 77 FR 13131 - Proposed Collection: Comment Request Post-Award Reporting Requirements Including New Research...

    Science.gov (United States)

    2012-03-05

    ... represents a consolidation of post-award reporting requirements under the PRA, and includes the new Research... HUMAN SERVICES National Institutes of Health Proposed Collection: Comment Request Post-Award Reporting Requirements Including New Research Performance Progress Report Collection SUMMARY: In compliance with...

  15. 25 CFR 1000.162 - What is included in a self-governance compact?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false What is included in a self-governance compact? 1000.162...-DETERMINATION AND EDUCATION ACT Negotiation Process for Annual Funding Agreements Negotiating A Self-Governance Compact § 1000.162 What is included in a self-governance compact? A model format for...

  16. 75 FR 11922 - Apria Healthcare, Including On-Site Leased Workers From Corestaff, Ultimate Staffing (Roth...

    Science.gov (United States)

    2010-03-12

    ... Employment and Training Administration Apria Healthcare, Including On-Site Leased Workers From Corestaff... Healthcare, including on-site leased workers from Corestaff, Cromwell, Connecticut. The notice was published in the Federal Register on January 25, 2010 (75 FR 3938). At the request of the State agency,...

  17. 26 CFR 48.4216(a)-1 - Charges to be included in sale price.

    Science.gov (United States)

    2010-04-01

    ... sales promotion programs, or otherwise. With respect to the rules relating to exclusion (in the case of... 26 Internal Revenue 16 2010-04-01 2010-04-01 true Charges to be included in sale price. 48.4216(a... to Manufacturers Taxes § 48.4216(a)-1 Charges to be included in sale price. (a) In general....

  18. 7 CFR 981.441 - Credit for market promotion activities, including paid advertising.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Credit for market promotion activities, including paid... promotion activities, including paid advertising. (a) In order for a handler to receive credit for his/her... each activity shall be to promote the sale, consumption or use of California almonds, and...

  19. 40 CFR 60.2630 - What should I include in my waste management plan?

    Science.gov (United States)

    2010-07-01

    ... or Before November 30, 1999 Model Rule-Waste Management Plan § 60.2630 What should I include in my waste management plan? A waste management plan must include consideration of the reduction or separation... of recyclable materials. The plan must identify any additional waste management measures, and...

  20. 40 CFR 60.3012 - What should I include in my waste management plan?

    Science.gov (United States)

    2010-07-01

    ..., 2004 Model Rule-Waste Management Plan § 60.3012 What should I include in my waste management plan? A waste management plan must include consideration of the reduction or separation of waste-stream elements.... The plan must identify any additional waste management measures and implement those measures...

  1. 7 CFR 330.302 - Domestic movements of earth (including soil), stone, etc.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false Domestic movements of earth (including soil), stone...; GENERAL; PLANT PESTS; SOIL, STONE, AND QUARRY PRODUCTS; GARBAGE Movement of Soil, Stone, And Quarry Products § 330.302 Domestic movements of earth (including soil), stone, etc. The interstate movement...

  2. 20 CFR 404.1322 - Post-World War II service included.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Post-World War II service included. 404.1322... II Veterans § 404.1322 Post-World War II service included. Your service was in the active service of the United States during the post-World War II period if you were in the— (a) Air Force, Army,...

  3. 77 FR 62265 - Long Elevator & Machine Company, Inc., Including Workers Whose Wages Were Reported Through Kone...

    Science.gov (United States)

    2012-10-12

    ... June 6, 2012 (77 FR 33490). The workers' firm was engaged in activities related to the supply of... Employment and Training Administration Long Elevator & Machine Company, Inc., Including Workers Whose Wages... Reconsideration for workers and former workers of Long Elevator & Machine Company, Inc., including workers...

  4. 38 CFR 17.255 - Applications for grants for programs which include construction projects.

    Science.gov (United States)

    2010-07-01

    ... specifications for the construction project, and where applicable, sufficient explanations of technical... for programs which include construction projects. 17.255 Section 17.255 Pensions, Bonuses, and... Applications for grants for programs which include construction projects. In addition to the documents...

  5. 42 CFR 137.327 - May multiple projects be included in a single construction project agreement?

    Science.gov (United States)

    2010-10-01

    ... construction project agreement? 137.327 Section 137.327 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF...-GOVERNANCE Construction Project Assumption Process § 137.327 May multiple projects be included in a single construction project agreement? Yes, a Self-Governance Tribe may include multiple projects in a...

  6. 76 FR 13663 - Celestica, Including On-Site Leased Workers From Adecco, Aerotek, Purchasing Professionals...

    Science.gov (United States)

    2011-03-14

    ... 3, 2009, applicable to workers of Celestica, including on-site leased workers from Adecco, Aerotek and Purchasing Professionals. The notice was published in the Federal Register on March 3, 2009 (74 FR... Employment and Training Administration Celestica, Including On-Site Leased Workers From Adecco,...

  7. 42 CFR 137.42 - What Tribal shares may be included in a funding agreement?

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false What Tribal shares may be included in a funding agreement? 137.42 Section 137.42 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN... Agreements § 137.42 What Tribal shares may be included in a funding agreement? All Tribal shares...

  8. Innovations in Teaching: How Novice Teaching Assistants Include LGBTQ Topics in the Writing Classroom

    Science.gov (United States)

    Jaekel, Kathryn S.

    2016-01-01

    This article examines how three novice graduate teaching assistants included lesbian, gay, bisexual, transgender, and queer topics in their first-year writing classrooms. Findings suggest that inclusion of these topics can be successfully done through attention to identity in the classroom, including current-day events, and structuring classroom…

  9. 10 CFR 719.10 - What information must be included in the legal management plan?

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false What information must be included in the legal management plan? 719.10 Section 719.10 Energy DEPARTMENT OF ENERGY CONTRACTOR LEGAL MANAGEMENT REQUIREMENTS Legal Management Plan § 719.10 What information must be included in the legal management plan? The legal...

  10. 78 FR 54487 - Abbott Laboratories; Diagnostic-Hematology; Including On-Site Leased Workers From Manpower...

    Science.gov (United States)

    2013-09-04

    ... Employment and Training Administration Abbott Laboratories; Diagnostic--Hematology; Including On-Site Leased... on-site at the Santa Clara, California location of Abbott Laboratories, Diagnostic--Hematology... International, reporting to Abbott Laboratories, Diagnostic--Hematology division, including on-site...

  11. 75 FR 69469 - LSI Corporation, 1110 American Parkway, Including On-Site Leased Workers From Spinnaker...

    Science.gov (United States)

    2010-11-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR Employment and Training Administration LSI Corporation, 1110 American Parkway, Including On-Site Leased Workers From Spinnaker, Allentown, PA; LSI Corporation, 555 Union Boulevard, Including On-Site Leased Workers From Spinnaker, Allentown, PA;...

  12. An Initial Look at the Quality of Life of Malaysian Families That Include Children with Disabilities

    Science.gov (United States)

    Clark, M.; Brown, R.; Karrapaya, R.

    2012-01-01

    Background: While there is a growing body of literature in the quality of life of families that include children with disabilities, the majority of research has been conducted in western countries. The present study provides an initial exploration of the quality of life of Malaysian families that include children with developmental/intellectual…

  13. 78 FR 47410 - Certain Wireless Devices, Including Mobile Phones and Tablets Institution of Investigation

    Science.gov (United States)

    2013-08-05

    ... COMMISSION Certain Wireless Devices, Including Mobile Phones and Tablets Institution of Investigation AGENCY... Tariff Act of 1930, as amended, 19 U.S.C. 1337, on behalf of Pragmatus Mobile, ] LLC of Alexandria... within the United States after importation of certain wireless devices, including mobile phones...

  14. 78 FR 40171 - Certain Wireless Devices, Including Mobile Phones and Tablets; Notice Of Receipt of Complaint...

    Science.gov (United States)

    2013-07-03

    ... COMMISSION Certain Wireless Devices, Including Mobile Phones and Tablets; Notice Of Receipt of Complaint... complaint entitled Certain Wireless Devices, Including Mobile Phones and Tablets, DN 2964; the Commission is... Commission's Rules of Practice and Procedure filed on behalf of Pragmatus Mobile, LLC on June 27, 2013....

  15. 47 CFR 15.115 - TV interface devices, including cable system terminal devices.

    Science.gov (United States)

    2010-10-01

    .... For all other TV interface devices, the wires or coaxial cables used to couple the output signals to... 47 Telecommunication 1 2010-10-01 2010-10-01 false TV interface devices, including cable system... FREQUENCY DEVICES Unintentional Radiators § 15.115 TV interface devices, including cable system...

  16. 41 CFR 105-68.220 - Are any procurement contracts included as covered transactions?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Are any procurement contracts included as covered transactions? 105-68.220 Section 105-68.220 Public Contracts and Property...) Covered Transactions § 105-68.220 Are any procurement contracts included as covered transactions?...

  17. 75 FR 28295 - Cummins Filtration, Including On-Site Leased Workers From Manpower and Spherion Staffing...

    Science.gov (United States)

    2010-05-20

    ... workers of Cummins Filtration, including on-site leased workers from Manpower, Lake Mills, Iowa. The notice was published in the Federal Register on December 11, 2009 (74 FR 65798). At the request of the... Employment and Training Administration Cummins Filtration, Including On-Site Leased Workers From Manpower...

  18. 25 CFR 20.401 - What is included under Services to Children, Elderly, and Families?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What is included under Services to Children, Elderly, and... FINANCIAL ASSISTANCE AND SOCIAL SERVICES PROGRAMS Services to Children, Elderly, and Families § 20.401 What is included under Services to Children, Elderly, and Families? Services to Children, Elderly,...

  19. 75 FR 4583 - In the Matter of: Certain Electronic Devices, Including Mobile Phones, Portable Music Players...

    Science.gov (United States)

    2010-01-28

    ... COMMISSION In the Matter of: Certain Electronic Devices, Including Mobile Phones, Portable Music Players, and... electronic devices, including mobile phones, portable music players, and computers, by reason of infringement... mobile phones, portable music players, or computers that infringe one or more of claims 1-12 of...

  20. 20 CFR 410.450 - Death due to pneumoconiosis, including statutory presumption.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Death due to pneumoconiosis, including... Death Due to Pneumoconiosis § 410.450 Death due to pneumoconiosis, including statutory presumption... at the time of his death, or whose death is determined to have been due to pneumoconiosis....

  1. 7 CFR 319.56-20 - Apples and pears from Australia (including Tasmania) and New Zealand.

    Science.gov (United States)

    2010-01-01

    ...) and New Zealand. 319.56-20 Section 319.56-20 Agriculture Regulations of the Department of Agriculture... Fruits and Vegetables § 319.56-20 Apples and pears from Australia (including Tasmania) and New Zealand. Apples and pears from Australia (including Tasmania) and New Zealand may be imported only in...

  2. 40 CFR 262.105 - What must be included in the laboratory environmental management plan?

    Science.gov (United States)

    2010-07-01

    ... laboratory environmental management plan? 262.105 Section 262.105 Protection of Environment ENVIRONMENTAL... University Laboratories XL Project-Laboratory Environmental Management Standard § 262.105 What must be included in the laboratory environmental management plan? (a) Each University must include...

  3. Family Living/Including Sex Education 1985-86. OEA Evaluation Report.

    Science.gov (United States)

    Guerrero, Frank; And Others

    The 1985-86 implementation of the comprehensive, sequenced curriculum called Family Living Including Sex Education Program in the New York City public schools is evaluated in this document. Curriculum content includes human growth and development, family relationships, friendship, reproduction, decision-making, child sexual abuse, and acquired…

  4. 49 CFR 238.209 - Forward end structure of locomotives, including cab cars and MU locomotives.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Forward end structure of locomotives, including... SAFETY STANDARDS Specific Requirements for Tier I Passenger Equipment § 238.209 Forward end structure of locomotives, including cab cars and MU locomotives. (a)(1) The skin covering the forward-facing end of...

  5. 34 CFR 263.4 - What training costs may a Professional Development program include?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false What training costs may a Professional Development... GRANT PROGRAMS Professional Development Program § 263.4 What training costs may a Professional Development program include? (a) A Professional Development program may include, as training costs,...

  6. 45 CFR 1308.11 - Eligibility criteria: Hearing impairment including deafness.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Eligibility criteria: Hearing impairment including deafness. 1308.11 Section 1308.11 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE... impairment including deafness. (a) A child is classified as deaf if a hearing impairment exists which is...

  7. 77 FR 24514 - Certain Consumer Electronics, Including Mobile Phones and Tablets; Institution of Investigation...

    Science.gov (United States)

    2012-04-24

    ... COMMISSION Certain Consumer Electronics, Including Mobile Phones and Tablets; Institution of Investigation... consumer electronics, including mobile phones and tablets, by reason of infringement of certain claims of U... importation, or the sale within the United States after importation of certain consumer electronics,...

  8. 78 FR 48468 - Delphi Corporation, Electronics and Safety Division, Including On-Site Leased Workers From...

    Science.gov (United States)

    2013-08-08

    ... determination was published in the Federal Register on June 10, 2013 (Volume 78 FR Pages 34672-34674). At the... Employment and Training Administration Delphi Corporation, Electronics and Safety Division, Including On-Site... to workers of Delphi Corporation, Electronics and Safety Division, including on-site leased...

  9. 29 CFR 779.259 - What is included in annual gross volume.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false What is included in annual gross volume. 779.259 Section... Coverage Annual Gross Volume of Sales Made Or Business Done § 779.259 What is included in annual gross volume. (a) The annual gross volume of sales made or business done of an enterprise consists of its...

  10. Systems and strippable coatings for decontaminating structures that include porous material

    Energy Technology Data Exchange (ETDEWEB)

    Fox, Robert V. (Idaho Falls, ID); Avci, Recep (Bozeman, MT); Groenewold, Gary S. (Idaho Falls, ID)

    2011-12-06

    Methods of removing contaminant matter from porous materials include applying a polymer material to a contaminated surface, irradiating the contaminated surface to cause redistribution of contaminant matter, and removing at least a portion of the polymer material from the surface. Systems for decontaminating a contaminated structure comprising porous material include a radiation device configured to emit electromagnetic radiation toward a surface of a structure, and at least one spray device configured to apply a capture material onto the surface of the structure. Polymer materials that can be used in such methods and systems include polyphosphazine-based polymer materials having polyphosphazine backbone segments and side chain groups that include selected functional groups. The selected functional groups may include iminos, oximes, carboxylates, sulfonates, .beta.-diketones, phosphine sulfides, phosphates, phosphites, phosphonates, phosphinates, phosphine oxides, monothio phosphinic acids, and dithio phosphinic acids.

  11. Methods of using structures including catalytic materials disposed within porous zeolite materials to synthesize hydrocarbons

    Science.gov (United States)

    Rollins, Harry W.; Petkovic, Lucia M.; Ginosar, Daniel M.

    2011-02-01

    Catalytic structures include a catalytic material disposed within a zeolite material. The catalytic material may be capable of catalyzing a formation of methanol from carbon monoxide and/or carbon dioxide, and the zeolite material may be capable of catalyzing a formation of hydrocarbon molecules from methanol. The catalytic material may include copper and zinc oxide. The zeolite material may include a first plurality of pores substantially defined by a crystal structure of the zeolite material and a second plurality of pores dispersed throughout the zeolite material. Systems for synthesizing hydrocarbon molecules also include catalytic structures. Methods for synthesizing hydrocarbon molecules include contacting hydrogen and at least one of carbon monoxide and carbon dioxide with such catalytic structures. Catalytic structures are fabricated by forming a zeolite material at least partially around a template structure, removing the template structure, and introducing a catalytic material into the zeolite material.

  12. New Nuclear Materials Including Non Metallic Fuel Elements. Vol. I. Proceedings of the Conference on New Nuclear Materials Technology, Including Non Metallic Fuel Elements

    International Nuclear Information System (INIS)

    One of the major aims of the International Atomic Energy Agency in furthering the peaceful uses of atomic energy is to encourage the development of economical nuclear power. Certainly, one of the more obvious methods of producing economical nuclear power is the development of economical fuels that can be used at high temperatures for long periods of time, and which have sufficient strength and integrity to operate under these conditions without permitting the release of fission products. In addition it is desirable that after irradiation these new fuels be economically reprocessed to reduce further the cost of the fuel cycle. As nuclear power becomes more and more competitive with conventional power the interest in new and more efficient higher-temperature fuels naturally increases rapidly. For these reasons, the Agency organized a Conference on New Nuclear Materials Technology, Including Non-Metallic Fuel Elements, which was held from 1 to 5 July 1963 at the International Hotel, Prague, with the assistance and co-operation of the Government of the Czechoslovak Socialist Republic. A total of 151 scientists attended, from 23 countries and 4 international organizations. The participants heard and discussed more than 60 scientific papers

  13. Jet engine nozzle exit configurations, including projections oriented relative to pylons, and associated systems and methods

    Science.gov (United States)

    Mengle, Vinod G. (Inventor); Thomas, Russell H. (Inventor)

    2012-01-01

    Nozzle exit configurations and associated systems and methods are disclosed. An aircraft system in accordance with one embodiment includes a jet engine exhaust nozzle having an internal flow surface and an exit aperture, with the exit aperture having a perimeter that includes multiple projections extending in an aft direction. Aft portions of individual neighboring projections are spaced apart from each other by a gap, and a geometric feature of the multiple can change in a monotonic manner along at least a portion of the perimeter. Projections near a support pylon and/or associated heat shield can have particular configurations, including greater flow immersion than other projections.

  14. Electrical machines and assemblies including a yokeless stator with modular lamination stacks

    Science.gov (United States)

    Qu, Ronghai; Jansen, Patrick Lee; Bagepalli, Bharat Sampathkumar; Carl, Jr., Ralph James; Gadre, Aniruddha Dattatraya; Lopez, Fulton Jose

    2010-04-06

    An electrical machine includes a rotor with an inner rotor portion and an outer rotor portion, and a double-sided yokeless stator. The yokeless stator includes modular lamination stacks and is configured for radial magnetic flux flow. The double-sided yokeless stator is concentrically disposed between the inner rotor portion and the outer rotor portion of the electrical machine. Examples of particularly useful embodiments for the electrical machine include wind turbine generators, ship propulsion motors, switch reluctance machines and double-sided synchronous machines.

  15. Turbomachine combustor nozzle including a monolithic nozzle component and method of forming the same

    Energy Technology Data Exchange (ETDEWEB)

    Stoia, Lucas John; Melton, Patrick Benedict; Johnson, Thomas Edward; Stevenson, Christian Xavier; Vanselow, John Drake; Westmoreland, James Harold

    2016-02-23

    A turbomachine combustor nozzle includes a monolithic nozzle component having a plate element and a plurality of nozzle elements. Each of the plurality of nozzle elements includes a first end extending from the plate element to a second end. The plate element and plurality of nozzle elements are formed as a unitary component. A plate member is joined with the nozzle component. The plate member includes an outer edge that defines first and second surfaces and a plurality of openings extending between the first and second surfaces. The plurality of openings are configured and disposed to register with and receive the second end of corresponding ones of the plurality of nozzle elements.

  16. New Nuclear Materials Including Non Metallic Fuel Elements. Vol. II. Proceedings of the Conference on New Nuclear Materials Technology, Including Non Metallic Fuel Elements

    International Nuclear Information System (INIS)

    One of the major aims of the International Atomic Energy Agency in furthering the peaceful uses of atomic energy is to encourage the development of economical nuclear power. Certainly, one of the more obvious methods of producing economical nuclear power is the development of economical fuels that can be used at high temperatures for long periods of time, and which have sufficient strength and integrity to operate under these conditions without permitting the release of fission products. In addition it is desirable that after irradiation these new fuels be economically reprocessed to reduce further the cost of the fuel cycle. As nuclear power becomes more and more competitive with conventional power the interest in new and more efficient higher-temperature fuels naturally increases rapidly. For these reasons, the Agency organized a Conference on New Nuclear Materials Technology, Including Non-Metallic Fuel Elements, which was held from 1 to 5 July 1963 at the International Hotel, Prague, with the assistance and co-operation of the Government of the Czechoslovak Socialist Republic. A total of 151 scientists attended, from 23 countries and 4 international organizations. The participants heard and discussed more than 60 scientific papers. The Agency wishes to thank the scientists who attended this Conference for their papers and for many spirited discussions that truly mark a successful meeting. The Agency wishes also to record its gratitude for the assistance and generous hospitality accorded the Conference, the participants and the Agency's staff by the Government of the Czechoslovak Socialist Republic and by the people of Prague. The scientific information contained in these Proceedings should help to quicken the pace of progress in the fabrication of new and m ore economical fuels, and it is hoped that these proceedings will be found useful to all workers in this and related fields

  17. 78 FR 8435 - Importation of Fresh Citrus Fruit From Uruguay, Including Citrus Hybrids and Fortunella

    Science.gov (United States)

    2013-02-06

    ... Animal and Plant Health Inspection Service 7 CFR Part 319 RIN 0579-AD59 Importation of Fresh Citrus Fruit From Uruguay, Including Citrus Hybrids and Fortunella spp., Into the Continental United States AGENCY.... australis. \\2\\...

  18. CT and MRI of the skull base, including the cranial nerves

    International Nuclear Information System (INIS)

    Some considerations about nuclear magnetic resonance and computerized tomography, essential for examining skull base lesions are treated here, including the cranial nerves. Neoplasms such as meningiomas, adenomas, chordomas, chondrosarcomas and others tumors are also cited, mentioning some commentaries. (author)

  19. 75 FR 20387 - Contech Castings, LLC, Including Workers Whose Unemployment Insurance (UI) Wages Are Reported...

    Science.gov (United States)

    2010-04-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR Employment and Training Administration Contech Castings, LLC, Including Workers Whose Unemployment Insurance... subject firm had their wages reported under a separate unemployment insurance (UI) tax account under...

  20. 75 FR 22630 - Vital Signs Minnesota, Inc., Including Workers Whose Unemployment Insurance (UI) Wages Are Paid...

    Science.gov (United States)

    2010-04-29

    ... FR 59253). At the request of the State, the Department reviewed the certification for workers of the... Employment and Training Administration Vital Signs Minnesota, Inc., Including Workers Whose Unemployment... separate unemployment insurance (UI) tax account under the name Biomedical Dynamics...

  1. Study on specific enthalpy of ice including solute in aqueous solution

    Energy Technology Data Exchange (ETDEWEB)

    Kumano, Hiroyuki; Hirata, Tetsuo; Izumi, Yasuyuki [Department of Mechanical Systems Engineering, Shinshu University, 4-17-1 Wakasato, Nagano 380-8553 (Japan)

    2010-05-15

    Effects of solute included in a sample on the specific enthalpy of ice are investigated experimentally. In the experiments, ice including the solute was made from an aqueous solution, and the specific enthalpy was measured by melting the ice in the aqueous solution. Moreover, a physical model of the ice including the solute is proposed. As a result, when the concentration of the aqueous solution is set at a value equivalent to the concentration of the sample, the specific enthalpy of the sample increases with the concentration of the sample. The measurement results and the calculated values agree well, and it was found that the method for calculating the specific enthalpy of the sample is valid. Moreover, when the concentration of the aqueous solution is higher than that of the ice including the solute, it was found the calculation method for the specific enthalpy of the sample is appropriate. (author)

  2. Electrode assemblies, plasma apparatuses and systems including electrode assemblies, and methods for generating plasma

    Science.gov (United States)

    Kong, Peter C; Grandy, Jon D; Detering, Brent A; Zuck, Larry D

    2013-09-17

    Electrode assemblies for plasma reactors include a structure or device for constraining an arc endpoint to a selected area or region on an electrode. In some embodiments, the structure or device may comprise one or more insulating members covering a portion of an electrode. In additional embodiments, the structure or device may provide a magnetic field configured to control a location of an arc endpoint on the electrode. Plasma generating modules, apparatus, and systems include such electrode assemblies. Methods for generating a plasma include covering at least a portion of a surface of an electrode with an electrically insulating member to constrain a location of an arc endpoint on the electrode. Additional methods for generating a plasma include generating a magnetic field to constrain a location of an arc endpoint on an electrode.

  3. IPM strategies and their dilemmas including an introduction to www.Eurowheat.org

    DEFF Research Database (Denmark)

    Jørgensen, Lise Nistrup; Hovmøller, Mogens Støvring; Hansen, Jens Grønbech;

    2014-01-01

    Information about disease management in winter wheat (Triticum aestiva) in eight European countries was collated and analysed by scientists and extension workers within a European Network for Durable Exploitation (ENDURE). This included information about specific disease thresholds, decision...

  4. 30 CFR 250.415 - What must my casing and cementing programs include?

    Science.gov (United States)

    2010-07-01

    ... effect, proper anchorage, and well control. (e) A statement of how you evaluated the best practices included in API RP 65, Recommended Practice for Cementing Shallow Water Flow Zones in Deep Water...

  5. 78 FR 21879 - Improving 9-1-1 Reliability; Reliability and Continuity of Communications Networks, Including...

    Science.gov (United States)

    2013-04-12

    ... From the Federal Register Online via the Government Publishing Office FEDERAL COMMUNICATIONS COMMISSION 47 CFR Chapter I Improving 9-1-1 Reliability; Reliability and Continuity of Communications Networks, Including Broadband Technologies AGENCY: Federal Communications Commission. ACTION: Notice...

  6. Differential two-body compound nuclear cross section, including the width-fluctuation corrections

    Energy Technology Data Exchange (ETDEWEB)

    Brown, D. [Brookhaven National Lab. (BNL), Upton, NY (United States). NNDC; Herman, M. [Brookhaven National Lab. (BNL), Upton, NY (United States). NNDC

    2014-09-02

    We figure out the compound angular differential cross sections, following mainly Fröbrich and Lipperheide, but with the angular momentum couplings that make sense for optical model work. We include the width-fluctuation correction along with calculations.

  7. 40 CFR 62.14740 - What must I include in the deviation report?

    Science.gov (United States)

    2010-07-01

    ... POLLUTANTS Federal Plan Requirements for Commercial and Industrial Solid Waste Incineration Units That... include in the deviation report? In each report required under § 62.14735, for any pollutant or...

  8. 77 FR 59985 - Healthcare Corporation of America (HCA), HCA Mountain Division Including Workers Whose Wages Were...

    Science.gov (United States)

    2012-10-01

    ... Employment and Training Administration Healthcare Corporation of America (HCA), HCA Mountain Division... of Healthcare Corporation of America (HCA), HCA Mountain Division, Cottonwood Heights, Utah (subject... follows: All workers of Healthcare Corporation of America (HCA), HCA Mountain Division, including...

  9. Computers in the University's Curriculum: The Theoretical Arguments for Including Computers in Telecommunications.

    Science.gov (United States)

    Eastman, Susan T.

    1984-01-01

    Argues that the telecommunications field has specific computer applications; therefore courses on how to use computer programs for audience analysis, station accounting, newswriting, etc., should be included in the telecommunications curriculum. (PD)

  10. Aids to Navigation for US waters, including territories, as of April 2015

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Structures intended to assist a navigator to determine position or safe course, or to warn of dangers or obstructions to navigation. This dataset includes lights,...

  11. U.S. Coastal Lidar Elevation Data - Including the Great Lakes and Territories, 1996 - present

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The NOAA Coastal Services Center manages and distributes lidar data for the coastal United States, including territorial possessions via the Digital Coast Data...

  12. 78 FR 34132 - Certain Portable Electronic Communications Devices, Including Mobile Phones and Components...

    Science.gov (United States)

    2013-06-06

    ... published a notice (78 FR 12892, May 31, 2013) of receipt of complaint entitled Certain Portable Electronic... From the Federal Register Online via the Government Publishing Office INTERNATIONAL TRADE COMMISSION Certain Portable Electronic Communications Devices, Including Mobile Phones and Components...

  13. 77 FR 4368 - Abbott Laboratories, Diagnostics Division, Including On-Site Leased Workers From Manpower...

    Science.gov (United States)

    2012-01-27

    ... Employment and Training Administration Abbott Laboratories, Diagnostics Division, Including On-Site Leased... for Worker Adjustment Assistance on February 24, 2011, applicable to workers of Abbott Laboratories... location of Abbott Laboratories, Diagnostics Division. The Department has determined that these...

  14. 40 CFR 60.2958 - What must I include in the deviation report?

    Science.gov (United States)

    2010-07-01

    ... Qualification Recordkeeping and Reporting § 60.2958 What must I include in the deviation report? In each report... incidents (other than downtime associated with zero, span, and other routine calibration checks)....

  15. Map Service Showing Geology, Oil and Gas Fields, and Geologic Provinces of Europe including Turkey

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This digitally compiled map includes geology, oil and gas fields, and geologic provinces of Europe. The oil and gas map is part of a worldwide series released on...

  16. 36 CFR 51.5 - What information will the prospectus include?

    Science.gov (United States)

    2010-07-01

    ..., include, but are not limited to the following: (1) The minimum acceptable franchise fee or other forms of... out by department for the three most recent years; franchise fees charged under the current...

  17. 78 FR 34669 - Certain Electronic Devices, Including Wireless Communication Devices, Portable Music and Data...

    Science.gov (United States)

    2013-06-10

    ... COMMISSION Certain Electronic Devices, Including Wireless Communication Devices, Portable Music and Data..., California (``Apple''), from importing wireless communication devices, portable music and data processing... Telecommunications America, LLC of Richardson, Texas (collectively, ``Samsung''). 76 FR 45860 (Aug. 1, 2011)....

  18. 78 FR 69878 - First Advantage Corporation, Including On-Site Leased Workers From Tapfin, Staffworks, Aerotek...

    Science.gov (United States)

    2013-11-21

    ... Employment and Training Administration First Advantage Corporation, Including On-Site Leased Workers From... Staffing, St. Petersburg, Florida; First Advantage Corporation, Charlotte, North Carolina, First Advantage Corporation, Bolingbrook, Illinois; First Advantage Corporation, Dallas, Texas; First Advantage...

  19. 77 FR 3793 - Certain Liquid Crystal Display Devices, Including Monitors, Televisions, and Modules, and...

    Science.gov (United States)

    2012-01-25

    ... From the Federal Register Online via the Government Publishing Office INTERNATIONAL TRADE COMMISSION Certain Liquid Crystal Display Devices, Including Monitors, Televisions, and Modules, and Components Thereof; Request for Statements on the Public Interest AGENCY: U.S. International Trade...

  20. 76 FR 23812 - Reliability and Continuity of Communications Networks, Including Broadband Technologies; Effects...

    Science.gov (United States)

    2011-04-28

    ... Documents in Rulemaking Proceedings, 63 FR 24121 (1998). Electronic Filers: Comments may be filed... COMMISSION Reliability and Continuity of Communications Networks, Including Broadband Technologies; Effects on Broadband Communications Networks of Damage or Failure of Network Equipment or Severe...

  1. Eleven leaflets for patients and visitors on healthcare associated infections - including accessible formats

    OpenAIRE

    Public Health Agency

    2015-01-01

    The following suite of nine leaflets for patients and visitors to healthcare settings include information on healthcare associated infections, C. difficile, MRSA, norovirus, scabies, ESBL resistant bacteria, multi-drug resistant bacteria and laundry and hand hygiene guidance.

  2. Multi-Objective Dynamic Economic Dispatch of Microgrid Systems Including Vehicle-to-Grid

    OpenAIRE

    Haitao Liu; Yu Ji; Huaidong Zhuang; Hongbin Wu

    2015-01-01

    Based on the characteristics of electric vehicles (EVs), this paper establishes the load models of EVs under the autonomous charging mode and the coordinated charging and discharging mode. Integrating the EVs into a microgrid system which includes wind turbines (WTs), photovoltaic arrays (PVs), diesel engines (DEs), fuel cells (FCs) and a storage battery (BS), this paper establishes multi-objective economic dispatch models of a microgrid, including the lowest operating cost, the least carbon ...

  3. High-Resolution Panchromatic Spectral Models of Galaxies including Photoionisation and Dust

    OpenAIRE

    Jonsson, Patrik; Groves, Brent; Cox, T. J.

    2009-01-01

    An updated version of the dust radiation transfer code Sunrise, including models for star-forming regions and a self-consistent calculation of the spatially dependent dust and PAH emission, is presented. Given a hydrodynamic simulation of a galaxy, this model can calculate a realistic 2-dimensional ultraviolet--submillimeter spectral energy distribution of the galaxy, including emission lines from HII regions, from any viewpoint. To model the emission from star-forming regions, the MAPPINGSII...

  4. DSM-V: modifying the postpartum-onset specifier to include hypomania

    OpenAIRE

    Sharma, Verinder; Burt, Vivien K.

    2010-01-01

    By failing to include it under the rubric of the postpartum-onset specifier, Diagnostic and Statistical Manual of Mental Disorders (DSM)-IV-TR has ignored the clinical reality that childbirth is a potent trigger of hypomania. Given the serious and occasionally tragic consequences of misdiagnosis of bipolar II depression as unipolar depression in the postpartum period, it is argued that DSM-V should consider modifying the postpartum-onset specifier to include episodes of hypomania.

  5. Assumptions for Including Organic Food in the Gastronomic Offering of Istrian Agritourism

    OpenAIRE

    Pavlo Ružić; Ivana Medica

    2009-01-01

    The authors of this research analyze assumptions to including organic food in the gastronomic offering of Istrians agritourism. They assume that gastronomic offering of Istrian agritourism that includes organic food would be more acceptable and competitive on the tourist market. The authors analyzed their assumptions using surveys conducted in 2007 and 2008 on tourists in Istra to learn whether they prefer organic food, does organic food match modern tourist trends, and are they willing to pa...

  6. Nonlocal photopolymerization kinetics including multiple termination mechanisms and dark reactions. Part I. Modeling

    OpenAIRE

    Gleeson, M. R.; Sheridan, John T.

    2009-01-01

    The photochemical processes present during free-radical-based holographic grating formation are examined. A kinetic model is presented, which includes, in a more nearly complete and physically realistic way, most of the major photochemical and nonlocal photopolymerization-driven diffusion effects. These effects include: (i) nonsteady-state kinetics (ii) spatially and temporally nonlocal polymer chain growth (iii) time varying photon absorption (iv) diffusion controlled viscosity effects (v) m...

  7. Circular geodesics and accretion disk in the spacetime of a black hole including global monopole

    International Nuclear Information System (INIS)

    We study circular time-like geodesics in the spacetime of a black hole including global monopole. We show that when the range of parameter changed the properties of the circular geodesics and the radiation of accretion disks are different. It follows that the properties of the accretion disk around black hole including global monopole can be different from that of a disk around Schwarzschild black hole

  8. Assumptions for Including Organic Food in the Gastronomic Offering of Istrian Agritourism

    Directory of Open Access Journals (Sweden)

    Pavlo Ružić

    2009-01-01

    Full Text Available The authors of this research analyze assumptions to including organic food in the gastronomic offering of Istrians agritourism. They assume that gastronomic offering of Istrian agritourism that includes organic food would be more acceptable and competitive on the tourist market. The authors analyzed their assumptions using surveys conducted in 2007 and 2008 on tourists in Istra to learn whether they prefer organic food, does organic food match modern tourist trends, and are they willing to pay more for it.

  9. Social-pragmatic skills of deaf and hard of hearing preschool children (included in kindergarden)

    OpenAIRE

    Vidmar, Barbara

    2015-01-01

    Since more and more children with special needs are included in preschool programs, educators are more often in contact with deaf and partially deaf children. They have to provide optimal conditions for their development. The graduate thesis titled Sociopragmatic skills of hearing, deaf and partially deaf preschool children included in the kindergarten is focused on possible differences in sociopragmatic skills of the hearing and the deaf and partially deaf children. It consists of a theoreti...

  10. DSM-V: modifying the postpartum-onset specifier to include hypomania

    OpenAIRE

    Sharma, Verinder; Burt, Vivien K.

    2011-01-01

    By failing to include it under the rubric of the postpartum-onset specifier, Diagnostic and Statistical Manual of Mental Disorders (DSM)-IV-TR has ignored the clinical reality that childbirth is a potent trigger of hypomania. Given the serious and occasionally tragic consequences of misdiagnosis of bipolar II depression as unipolar depression in the postpartum period, it is argued that DSM-V should consider modifying the postpartum-onset specifier to include episodes of hypomania.

  11. Anàlisi de la dimensió de gènere en el marc del projecte INCLUD-ED per a desenvolupar pràctiques educatives inclusives Analysis of gender aspects in the framework of the INCLUD-ED project to develop inclusive educational practices Análisis de la dimensión de género en el marco del proyecto INCLUD-ED para desarrollar prácticas educativas inclusivas

    Directory of Open Access Journals (Sweden)

    Patricia Melgar

    2010-01-01

    ésultats académiquesVarious aspects, including gender, must be considered to boost the inclusivity of education. The risk of social exclusion may increase when gender is combined with other factors such as the cultural group, age or low socioeconomic level. Some studies have shown that there has been a significant improvement in girls’ academic results, which are better than those of boys in certain areas. However, the contribution of such studies is limited, as they describe the situation without examining its causes in-depth. This has led to new debates in the scientific community. The power relationships between the genders and the transmission traditional models of masculinity and femininity that can still be found in some school practices today have an impact on academic results.La promoción de la dimensión integradora de la educación debe contemplar las diferentes perspectivas, entre ellas la de género. El riesgo de exclusión social puede aumentar cuando la dimensión de género se combina con otras dimensiones como el grupo cultural, la edad o el bajo nivel socioeconómico. Algunos estudios indican que se ha producido una mejora significativa en los resultados académicos de las niñas, superando incluso los resultados de los niños en determinadas áreas. No obstante, las contribuciones aportadas son limitadas ya que describen la situación sin profundizar en las causas que llevan a esta situación. Ello ha reabierto recientemente nuevos debates en el marco de la comunidad científica. Las relaciones de poder entre género, así como la transmisión de modelos tradicionales de masculinidad y feminidad, que todavía se pueden observar hoy en día en algunas prácticas en las escuelas, tienen un impacto en los resultados académicos.

  12. The impact of onlooking and including bystander behaviour on judgments and emotions regarding peer exclusion.

    Science.gov (United States)

    Malti, Tina; Strohmeier, Dagmar; Killen, Melanie

    2015-09-01

    We investigated judgments and emotions in contexts of social exclusion that varied as a function of bystander behaviour (N = 173, 12- and 16-year-olds). Adolescents responded to film vignettes depicting a target excluded by a group with no bystanders, onlooking bystanders, or bystanders who included the target. Adolescents were asked to judge the behaviour and attribute emotions to the excluding group, the excluded target, and the bystanders. Younger adolescents judged the behaviour of the excluding group as more wrong than older adolescents when there were no bystanders present, indicating that the presence of bystanders was viewed as lessening the negative outcome of exclusion by the younger group. Yet, bystanders play a positive role only when they are includers, not when they are silent observers. This distinction was revealed by the findings that adolescents rated the behaviour of onlooking bystanders as more wrong compared with the behaviour of including bystanders. Moreover, all adolescents justified the inclusive behaviour more frequently with empathy than the onlooking behaviour. Adolescents also anticipated more empathy to including bystanders than to onlooking bystanders, as well as anticipated more guilt to onlooking bystanders than including bystanders. The findings are discussed in light of the role of group norms and group processes regarding bystanders' roles in social exclusion peer encounters. PMID:25953459

  13. Isospin mixing within relativistic mean-field models including the delta meson

    International Nuclear Information System (INIS)

    Full text: We investigate isospin mixing effects in the asymmetry as obtained in parity-violating electron scattering for selected spherical nuclei ranging from 4He to 208Pb. The scattering analysis is developed within plane and distorted wave Born approximations (PWBA and DWBA) accounting for nucleon form factors, which are given by the Galster parametrization. We use Walecka's Model (QHD), including the σ, ω, ρ and δ mesons as well as the electromagnetic interaction. The ρ meson effects are specially interesting once it should add a contribution for isospin mixing together with the electromagnetic and meson fields. Our model includes Lagrangians with non-linear terms as well as Lagrangians including density dependent couplings. The model is solved in a Hartree approximation with spherical symmetry using a self-consistent calculation by means of an expansion of the nuclear wave functions and potentials in an harmonic oscillator basis. For each kind of Lagrangian we use two different parametrizations, one including the ρ meson and another in which it is not included. In this way, the effects of the inclusion of that meson can be inferred. For non-linear Lagrangians, the NL3 and NLδparameter sets are used. For Lagrangians with density dependent couplings, the TW and a reparametrization of the DDHδ, modified to better reproduce the main nuclear properties, are used. (author)

  14. Processing negative valence of word pairs that include a positive word.

    Science.gov (United States)

    Itkes, Oksana; Mashal, Nira

    2016-09-01

    Previous research has suggested that cognitive performance is interrupted by negative relative to neutral or positive stimuli. We examined whether negative valence affects performance at the word or phrase level. Participants performed a semantic decision task on word pairs that included either a negative or a positive target word. In Experiment 1, the valence of the target word was congruent with the overall valence conveyed by the word pair (e.g., fat kid). As expected, response times were slower in the negative condition relative to the positive condition. Experiment 2 included target words that were incongruent with the overall valence of the word pair (e.g., fat salary). Response times were longer for word pairs whose overall valence was negative relative to positive, even though these word pairs included a positive word. Our findings support the Cognitive Primacy Hypothesis, according to which emotional valence is extracted after conceptual processing is complete. PMID:26008637

  15. Alcohol intake and colorectal cancer: a comparison of approaches for including repeated measures of alcohol consumption

    DEFF Research Database (Denmark)

    Thygesen, Lau Caspar; Wu, Kana; Grønbaek, Morten;

    2008-01-01

    BACKGROUND: In numerous studies, alcohol intake has been found to be positively associated with colorectal cancer risk. However, the majority of studies included only one exposure measurement, which may bias the results if long-term intake is relevant.METHODS: We compared different approaches for...... including repeated measures of alcohol intake among 47,432 US men enrolled in the Health Professionals Follow-up Study. Questionnaires including questions on alcohol intake had been completed in 1986, 1990, 1994, and 1998. The outcome was incident colorectal cancer during follow-up from 1986 to 2002.RESULTS......: During follow-up, 868 members of the cohort experienced colorectal cancer. Baseline, updated, and cumulative average alcohol intakes were positively associated with colorectal cancer, with only minor differences among the approaches. These results support moderately increased risk for intake >30 g/d and...

  16. Force measuring valve assemblies, systems including such valve assemblies and related methods

    Science.gov (United States)

    DeWall, Kevin George; Garcia, Humberto Enrique; McKellar, Michael George

    2012-04-17

    Methods of evaluating a fluid condition may include stroking a valve member and measuring a force acting on the valve member during the stroke. Methods of evaluating a fluid condition may include measuring a force acting on a valve member in the presence of fluid flow over a period of time and evaluating at least one of the frequency of changes in the measured force over the period of time and the magnitude of the changes in the measured force over the period of time to identify the presence of an anomaly in a fluid flow and, optionally, its estimated location. Methods of evaluating a valve condition may include directing a fluid flow through a valve while stroking a valve member, measuring a force acting on the valve member during the stroke, and comparing the measured force to a reference force. Valve assemblies and related systems are also disclosed.

  17. Fusion rules for the logarithmic $N=1$ superconformal minimal models II: including the Ramond sector

    CERN Document Server

    Canagasabey, Michael

    2015-01-01

    The Virasoro logarithmic minimal models were intensively studied by several groups over the last ten years with much attention paid to the fusion rules and the structures of the indecomposable representations that fusion generates. The analogous study of the fusion rules of the $N=1$ superconformal logarithmic minimal models was initiated in arXiv:1504.03155 as a continuum counterpart to the lattice explorations of arXiv:1312.6763. These works restricted fusion considerations to Neveu-Schwarz representations. Here, this is extended to include the Ramond sector. Technical advances that make this possible include a fermionic Verlinde formula applicable to logarithmic conformal field theories and a twisted version of the fusion algorithm of Nahm and Gaberdiel-Kausch. The results include the first construction and detailed analysis of logarithmic structures in the Ramond sector.

  18. EXACT SOLUTIONS FOR NONLINEAR TRANSIENT FLOW MODEL INCLUDING A QUADRATIC GRADIENT TERM

    Institute of Scientific and Technical Information of China (English)

    曹绪龙; 同登科; 王瑞和

    2004-01-01

    The models of the nonlinear radial flow for the infinite and finite reservoirs including a quadratic gradient term were presented. The exact solution was given in real space for flow equation including quadratic gradiet term for both constant-rate and constant pressure production cases in an infinite system by using generalized Weber transform. Analytical solutions for flow equation including quadratic gradient term were also obtained by using the Hankel transform for a finite circular reservoir case. Both closed and constant pressure outer boundary conditions are considered. Moreover, both constant rate and constant pressure inner boundary conditions are considered. The difference between the nonlinear pressure solution and linear pressure solution is analyzed. The difference may be reached about 8% in the long time. The effect of the quadratic gradient term in the large time well test is considered.

  19. Adolescent judgments and reasoning about the failure to include peers with social disabilities.

    Science.gov (United States)

    Bottema-Beutel, Kristen; Li, Zhushan

    2015-06-01

    Adolescents with autism spectrum disorder often do not have access to crucial peer social activities. This study examines how typically developing adolescents evaluate decisions not to include a peer based on disability status, and the justifications they apply to these decisions. A clinical interview methodology was used to elicit judgments and justifications across four contexts. We found adolescents are more likely to judge the failure to include as acceptable in personal as compared to public contexts. Using logistic regression, we found that adolescents are more likely to provide moral justifications as to why failure to include is acceptable in a classroom as compared to home, lab group, and soccer practice contexts. Implications for intervention are also discussed. PMID:25575622

  20. Cleanup and treatment of radioactively contaminated land including areas near nuclear facilities. A selected bibliography

    International Nuclear Information System (INIS)

    This annotated bibliography of 337 references summarizes the literature published on the cleanup and treatment of radioactively contaminated land. Specifically, this bibliography focuses on literature concerned with the methods of cleanup and treatment being applied - chemical, physical, or vegetative stabilization; the types of equipment being used; and the influence of climatic conditions on the method selected for use. The emphasis in such literature is placed on hazardous site cleanup efforts that have been completed as well as those that are in progress and are being planned. Appendix A includes 135 additional references to literature identified but not included in the bibliography because of time and funding constraints. Appendix B consists of a table that identifies the cleanup and treatment research conducted at specific sites. All of the information included in this bibliography is stored in a computerized form that is readily available upon request

  1. Coupled flexural-torsional vibration band gap in periodic beam including warping effect

    Institute of Scientific and Technical Information of China (English)

    Fang Jian-Yu; Yu Dian-Long; Han Xiao-Yun; Cai Li

    2009-01-01

    The propagation of coupled flexural-torsional vibration in the periodic beam including warping effect is investigated with the transfer matrix theory.The band structures of the periodic beam,both including warping effect and ignoring warping effect,are obtained.The frequency response function of the finite periodic beams is simulated with finite element method,which shows large vibration attenuation in the frequency range of the gap as expected.The effect of warping stiffness on the band structure is studied and it is concluded that substantial error can be produced in high frequency range if the effect is ignored.The result including warping effect agrees quite well with the simulated result.

  2. U.S. Geological Survey budget would increase but includes targeted cuts to some key programs

    Science.gov (United States)

    Showstack, Randy

    2012-03-01

    The Obama administration's proposed budget for the U.S. Geological Survey (USGS) for fiscal year (FY) 2013 is 1.1 billion, 34.5 million (3.2%) above the Agency's 2012 enacted level. The budget includes 73.2 million in targeted increases but also has 49.5 million in proposed reductions, including cuts to some water and minerals programs and other areas. Funding for the budget was prioritized to maintain programs that are legislatively mandated, that are important for protecting lives and human property, and that are among the Obama administration's key emphases. These include research and development, which the administration believes will help end the economic recession, USGS director Marcia McNutt said at a 14 February briefing.

  3. Improvement of prediction ability for genomic selection of dairy cattle by including dominance effects.

    Directory of Open Access Journals (Sweden)

    Chuanyu Sun

    Full Text Available Dominance may be an important source of non-additive genetic variance for many traits of dairy cattle. However, nearly all prediction models for dairy cattle have included only additive effects because of the limited number of cows with both genotypes and phenotypes. The role of dominance in the Holstein and Jersey breeds was investigated for eight traits: milk, fat, and protein yields; productive life; daughter pregnancy rate; somatic cell score; fat percent and protein percent. Additive and dominance variance components were estimated and then used to estimate additive and dominance effects of single nucleotide polymorphisms (SNPs. The predictive abilities of three models with both additive and dominance effects and a model with additive effects only were assessed using ten-fold cross-validation. One procedure estimated dominance values, and another estimated dominance deviations; calculation of the dominance relationship matrix was different for the two methods. The third approach enlarged the dataset by including cows with genotype probabilities derived using genotyped ancestors. For yield traits, dominance variance accounted for 5 and 7% of total variance for Holsteins and Jerseys, respectively; using dominance deviations resulted in smaller dominance and larger additive variance estimates. For non-yield traits, dominance variances were very small for both breeds. For yield traits, including additive and dominance effects fit the data better than including only additive effects; average correlations between estimated genetic effects and phenotypes showed that prediction accuracy increased when both effects rather than just additive effects were included. No corresponding gains in prediction ability were found for non-yield traits. Including cows with derived genotype probabilities from genotyped ancestors did not improve prediction accuracy. The largest additive effects were located on chromosome 14 near DGAT1 for yield traits for both

  4. A note on communicating between information systems based on including degrees

    CERN Document Server

    Zhu, Ping

    2010-01-01

    In order to study the communication between information systems, Gong and Xiao [Z. Gong and Z. Xiao, Communicating between information systems based on including degrees, International Journal of General Systems 39 (2010) 189--206] proposed the concept of general relation mappings based on including degrees. Some properties and the extension for fuzzy information systems of the general relation mappings have been investigated there. In this paper, we point out by counterexamples that several assertions (Lemma 3.1, Lemma 3.2, Theorem 4.1, and Theorem 4.3) in the aforementioned work are not true in general.

  5. An approach to include soil carbon changes in life cycle assessments

    DEFF Research Database (Denmark)

    Petersen, Bjørn Molt; Knudsen, Marie Trydeman; Hermansen, John Erik;

    2013-01-01

    to estimate carbon sequestration to be included in LCA is suggested and applied to two examples where the inclusion of carbon sequestration is especially relevant: 1) Bioenergy: removal of straw from a Danish soil for energy purposes and 2) Organic versus conventional farming: comparative study of...... soybean production in China. The suggested approach considers the time of the soil CO2 emissions for the LCA by including the Bern Carbon Cycle Model. Time perspectives of 20, 100 and 200 years are used and a soil depth of 0–100 cm is considered. The application of the suggested method showed that the...

  6. First-order symmetrizable hyperbolic formulations of Einstein's equations including lapse and shift as dynamical fields

    International Nuclear Information System (INIS)

    First-order hyperbolic systems are promising as a basis for numerical integration of Einstein's equations. In previous work, the lapse and shift have typically not been considered part of the hyperbolic system and have been prescribed independently. This can be expensive computationally, especially if the prescription involves solving elliptic equations. Therefore, including the lapse and shift in the hyperbolic system could be advantageous for numerical work. In this paper, two first-order symmetrizable hyperbolic systems are presented that include the lapse and shift as dynamical fields and have only physical characteristic speeds

  7. Health aspects of disaster preparedness and response--panel session 2: seismic risks including tsunamis.

    Science.gov (United States)

    2006-01-01

    This Panel Session consisted of five country reports (India, Indonesia, Maldives, Thailand, and Nepal) and the common issues identified during the Panel discussions relative to seismic events in the Southeast Asia Region. Important issues identified included the needs for: (1) a legal framework upon which to base preparedness and response; (2) coordination between the many organizations involved; (3) early warning systems within and between countries; (4) command and control; (5) access to resources including logistics; (6) strengthening the health infrastructure; (7) professionalizing the field of disaster medicine and management; (8) management of communications and information; (9) management of dead bodies; and (10) mental health of the survivors and health workers. PMID:17297912

  8. Consideration of Including Male Circumcision in the Indonesian HIV Prevention Strategy

    Directory of Open Access Journals (Sweden)

    IN Sutarsa

    2015-04-01

    Full Text Available Introduction HIV/AIDS is an emerging threat to population health. Globally, 33.4 million people were estimated to be living with HIV in 2008 including 2.1 million children.1,2 The total number of new cases was estimated to be 2.7 million people (including 430,000 children and HIV/AIDS related death was estimated to be 2.0 million in 2008.1 Sustainable prevention measures followed by care, support and treatment program is vital to reduce the incidence and prevalence of HIV/AIDS.

  9. Deliverable 4.2: Methodology for including specific biological effects and pathogen aspects into LCA

    DEFF Research Database (Denmark)

    Larsen, Henrik Fred; Olsen, Stig Irving; Hauschild, Michael Zwicky;

    2009-01-01

    methodology is presented here. Furthermore, special issues related to waste water have been addressed by including novel development on LCIA methodology for possible impact from pathogens and whole effluent toxicity. Special focus is also allocated to micropollutants with specific toxic mode of action (i....... 1997, Hauschild and Wenzel 1998) for which the impact assessment on toxicity is PNEC based. However, in order to include the newest development on especially best available practice as regards ecotoxicity a new revised and updated EDIP 200X LCIA methodology has been developed. A first draft of this...

  10. Sighting optics including an optical element having a first focal length and a second focal length

    Science.gov (United States)

    Crandall, David Lynn

    2011-08-01

    One embodiment of sighting optics according to the teachings provided herein may include a front sight and a rear sight positioned in spaced-apart relation. The rear sight includes an optical element having a first focal length and a second focal length. The first focal length is selected so that it is about equal to a distance separating the optical element and the front sight and the second focal length is selected so that it is about equal to a target distance. The optical element thus brings into simultaneous focus, for a user, images of the front sight and the target.

  11. Including 'positive handling strategies' within training in behaviour management: the 'Team-Teach' approach

    OpenAIRE

    Hayden, Carol; S. Pike

    2005-01-01

    This article reports on aspects of an evaluation of ‘Team-Teach’ - a ‘whole setting holistic’ approach to behaviour management in a range of child-care environments. A distinctive feature of Team-Teach is that it includes both training in de-escalation skills and physical interventions, known as ‘positive handling strategies’. The approach is clearly structured and calibrated against level of risk. It includes accreditation and re-accreditation of trainers. Findings from four case study educa...

  12. Environmental radioactivity in the North Atlantic region including the Faroe Islands and Greenland. 1990 and 1991

    International Nuclear Information System (INIS)

    Measurements of fallout radioactivity in the North Atlantic region including Faroe Islands and Greenland are reported. Strontium-90, cesium-137 and cesium-134 were determined in samples of precipitation, sea water, vegetation, various foodstuffs (including milk in the Faroes), and drinking water. Estimates are given of the mean contents of 90Sr and 137Cs in human diet in the Faroes and Greenland in 1990 and 1991. 99Tc data on marine samples, in particular sea water from the Greenland Sea, are reported. (au) (77 tabs., 46 ills., 8 refs.)

  13. Nonlocal photopolymerization kinetics including multiple termination mechanisms and dark reactions. Part I. Modeling

    Energy Technology Data Exchange (ETDEWEB)

    Gleeson, Michael R.; Sheridan, John T. [UCD School of Electrical, Electronic and Mechanical Engineering, UCD Optoelectronic Research Centre, and The SFI-Strategic Research Cluster in Solar Energy Conversion, College of Engineering, Mathematical and Physical Sciences, University College Dublin, Belfield, Dublin 4 (Ireland)

    2009-09-15

    The photochemical processes present during free-radical-based holographic grating formation are examined. A kinetic model is presented, which includes, in a more nearly complete and physically realistic way, most of the major photochemical and nonlocal photopolymerization-driven diffusion effects. These effects include: (i) non-steady-state kinetics (ii) spatially and temporally nonlocal polymer chain growth (iii) time varying photon absorption (iv) diffusion controlled viscosity effects (v) multiple termination mechanisms, and (vi) inhibition. The convergence of the predictions of the resulting model is then examined. Comparisons with experimental results are carried out in Part II of this series of papers [J. Opt. Soc. Am. B 26, 1746 (2009)].

  14. Nonlocal photopolymerization kinetics including multiple termination mechanisms and dark reactions. Part I. Modeling

    International Nuclear Information System (INIS)

    The photochemical processes present during free-radical-based holographic grating formation are examined. A kinetic model is presented, which includes, in a more nearly complete and physically realistic way, most of the major photochemical and nonlocal photopolymerization-driven diffusion effects. These effects include: (i) non-steady-state kinetics (ii) spatially and temporally nonlocal polymer chain growth (iii) time varying photon absorption (iv) diffusion controlled viscosity effects (v) multiple termination mechanisms, and (vi) inhibition. The convergence of the predictions of the resulting model is then examined. Comparisons with experimental results are carried out in Part II of this series of papers [J. Opt. Soc. Am. B 26, 1746 (2009)].

  15. Environmental radioactivity in the North Atlantic region including the Faroe Islands and Greenland

    International Nuclear Information System (INIS)

    Measurements of fallout radioactivity in the North Atlantic region including the Faroe Islands and Greenland are reported. Strontium-90, cesium-137 and cesium-134 were determined in samples of precipitation, sea water, vegetation, various foodstuffs (including milk in the Faroes), and drinking water. Estimates are given of the mean contents of 90Sr and 137Cs in human diet in the Faroes and Greenland in 1988 and 1989. 99Tc data on marine samples, in particular sea water from the Greenland Sea, are reported. (au) (91 taps., 51 ills., 7 refs.)

  16. Environmental radioactivity in the North Atlantic region including the Faroe Islands and Greenland. 1986

    International Nuclear Information System (INIS)

    Measurements of fallout radioactivity in the North Atlantic region including the Faroe Islands and Greenland are reported. Strontium-90 and cesium-137 were determined in samples of precipitation, sea water, vegetation, various foodstuffs (including milk in the Fareos) and drinking water. Estimates are given of the mean contents of 90Sr and 137Cs in human diet in the Faroes and Greenland in 1986. A few 99Tc data on marine samples are reported. Data on plutonium and americium in sediments and biota collected at Thule in 1984 are presented. (author)

  17. Environmental radioactivity in the North Atlantic region including the Faroe Islands and Greenland. 1987

    International Nuclear Information System (INIS)

    Measurements of fallout radioactivity in the North Atlantic region including the Faroe Islands and Greenland are reported. Strontium-90, cesium-137 and cesium-134 were determined in samples of precipitation, sea water, vegetation, various foodstuffs (including milk in the Faroes), and drinking water. Estimates are given of the mean contents of 90Sr and 137Cs in human diet in the Faroes and Greenland in 1987. 99Tc data on marine samples are reported. Data on plutonium and americium in sediments and biota collected at Thule in 1984 are presented. (author) 102 tabs., 35 ills., 15 refs

  18. Environmental radioactivity in the North Atlantic region including the Faroe Islands and Greenland. 1992 and 1993

    International Nuclear Information System (INIS)

    Measurements of fallout radioactivity in the North Atlantic region including Faroe Islands and Greenland are reported. Strontium-90, caesium-137 and caesium-134 were determined in samples of precipitation, sea water, vegetation, various foodstuffs (including milk in the Faroes), and drinking water. Estimates are given on the mean contents of 90Sr and 137Cs in human diet in the Faroes and Greenland in 1992 and 1993. Pu-239,240 data from a Canadian sediment-sampling at Thule in 1991 are reported. (au) 126 tabs., 63 ills., 17 refs

  19. Including the Z in an Effective Field Theory for dark matter at the LHC

    OpenAIRE

    Davidson, Sacha

    2014-01-01

    An Effective Field Theory for dark matter at a TeV-scale hadron collider should include contact interactions of dark matter with the partons, the Higgs and the Z . This note estimates the impact of including dark matter- Z interactions on the complementarity of spin dependent direct detection and LHC monojet searches for dark matter. The effect of the Z is small, because it interacts with quarks via small electroweak couplings, and the contact interaction self-consistency condition C /Λ 2  

  20. [Examples of textual research on gynecological literature included in Yong le da dian (Yongle's Great Canon)].

    Science.gov (United States)

    Zhang, Xue-dan; Zhang, Ru-qing

    2010-07-01

    Yongle's Great Canon is a series of books to be read exclusively by the emperors of the Ming Dynasty, so all of the books included are from many rare books collected in Wen Yuan Ge of early Ming Dynasty. These rare books, ranging from Song, Jin, and Yuan Dynasties or from folk sources preserve the original appearance of the ancient books almost without any changes. From a philological viewpoint, the gynecological books included in Yong le da dian are studied, proof-read and checked for its lost texts and different texts. This can serve as a basis for the reprinting and re-publishing of ancient TCM books. PMID:21122346

  1. 77 FR 15665 - Cellular Service, Including Changes in Licensing of Unserved Area; Interim Restrictions and...

    Science.gov (United States)

    2012-03-16

    ... the first time included mandatory coverage of geography (rather than population). In our proposed... of all areas or population centers in a geographic-based license. 33. We also seek comment on whether... bidding. Disputes over existing CGSA boundaries and the distribution of the remaining Unserved Area...

  2. 12 CFR 573.6 - Information to be included in privacy notices.

    Science.gov (United States)

    2010-01-01

    ... examples to illustrate the types of third parties in each category. (i) Financial service providers; (ii) Non-financial companies; and (iii) Others. (4) Disclosures under exception for service providers and... OF CONSUMER FINANCIAL INFORMATION Privacy and Opt Out Notices § 573.6 Information to be included...

  3. 50 CFR 15.33 - Species included in the approved list.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 1 2010-10-01 2010-10-01 false Species included in the approved list. 15.33 Section 15.33 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE.... Poephila cincta Parson finch. Poephila guttata Zebra finch. Poephila personata Masked finch....

  4. Ab initio calculation of the bcc Fe-Al phase diagram including magnetic interactions

    Energy Technology Data Exchange (ETDEWEB)

    Gonzales-Ormeno, Pablo Guillermo [Facultad de Ciencias Naturales y Matematica, Universidad Nacional Federico Villarreal, Calle San Marcos 351, Pueblo Libre, Lima (Peru); Departamento de Fisica dos Materiais e Mecanica, Instituto de Fisica da Universidade de Sao Paulo, CP 66318, CEP 05315-970 Sao Paulo-SP (Brazil); Computational Materials Science Lab., Departamento de Engenharia Metalurgica e de Materiais, Escola Politecnica da Universidade de Sao Paulo, Av. Prof. Mello Moraes, 2463, CEP 05508-900 Sao Paulo-SP (Brazil); Petrilli, Helena Maria [Departamento de Fisica dos Materiais e Mecanica, Instituto de Fisica da Universidade de Sao Paulo, CP 66318, CEP 05315-970 Sao Paulo-SP (Brazil)]. E-mail: hmpetril@macbeth.if.usp.br; Schoen, Claudio Geraldo [Computational Materials Science Lab., Departamento de Engenharia Metalurgica e de Materiais, Escola Politecnica da Universidade de Sao Paulo, Av. Prof. Mello Moraes, 2463, CEP 05508-900 Sao Paulo-SP (Brazil)]. E-mail: schoen@usp.br

    2006-04-15

    metastable phase diagram of the body-centered cubic-based ordering equilibria in the Fe-Al system has been calculated by the cluster expansion method, through the combination of the full potential-linear augmented plane wave and cluster variation methods. The results are discussed with reference to the effect of including the spin polarizations of Fe in the thermodynamic model.

  5. 75 FR 34170 - Circuit Science, Inc., Including Workers Whose Unemployment Insurance (UI) Wages Are Reported...

    Science.gov (United States)

    2010-06-16

    ... (75 FR 3929). At the request of the state, the Department reviewed the certification for workers of... Employment and Training Administration Circuit Science, Inc., Including Workers Whose Unemployment Insurance... subject firm had their wages reported under a separated unemployment insurance (UI) tax account under...

  6. 78 FR 39773 - Monta Vista Software, LLC, a Subsidiary of Cavium, Inc., Including Workers Whose Unemployment...

    Science.gov (United States)

    2013-07-02

    ... in the Federal Register on April 30, 2013 (78 FR 25306). At the request of the State agency, the... Workers Whose Unemployment Insurance (UI) Wages are Reported Through Trinet HR Corporation, Arlington, Texas; Monta Vista Software, LLC, a Subsidiary of Cavium, Inc., Including Workers Whose...

  7. 75 FR 43557 - Wire Products Company, Inc., Including Workers Whose Unemployment Insurance (UI) Wages Are Paid...

    Science.gov (United States)

    2010-07-26

    ... Register on May 28, 2010 (75 FR 30067). At the request of a company official, the Department reviewed the... Employment and Training Administration Wire Products Company, Inc., Including Workers Whose Unemployment... unemployment insurance (UI) tax account under the name Globe Pipe Hanger Products, Inc. Based on these...

  8. 77 FR 3500 - Hugo Boss Cleveland, Inc., Including Workers Whose Unemployment Insurance (UI) Wages Are Paid...

    Science.gov (United States)

    2012-01-24

    ... Cleveland, Inc., Brooklyn, Ohio. The notice was published in the Federal Register on May 5, 2010 (75 FR... Employment and Training Administration Hugo Boss Cleveland, Inc., Including Workers Whose Unemployment... location of Hugo Boss Cleveland, Inc. had their wages reported under a separate unemployment insurance...

  9. 75 FR 22846 - Norgren Automation Solutions, Including Workers Whose Unemployment Insurance (UI) Wages Are Paid...

    Science.gov (United States)

    2010-04-30

    ... published in the Federal Register on March 5, 2010 (75 FR 10320). At the request of the state, the... Employment and Training Administration Norgren Automation Solutions, Including Workers Whose Unemployment... under a separated unemployment insurance (UI) tax account under the name Syron Engineering....

  10. 76 FR 27366 - Blue Heron Paper Company, Including Workers Whose Unemployment Insurance (UI) Wages Are Paid...

    Science.gov (United States)

    2011-05-11

    ... 16, 2010 (75 FR 34174). At the request of the State agency, the Department reviewed the certification... Employment and Training Administration Blue Heron Paper Company, Including Workers Whose Unemployment... reported under a separated unemployment insurance (UI) tax account under the name Barrett Business...

  11. 77 FR 33490 - Long Elevator & Machine Company, Inc., Including Workers Whose Unemployment Insurance (UI) Wages...

    Science.gov (United States)

    2012-06-06

    ... was published in the Federal Register on April 10, 2012 (77 FR 21590). The subject firm is engaged in... Unemployment Insurance (UI) Wages Were Reported Through Kone, Inc., Riverton, IL; Notice of Affirmative...., including workers whose unemployment insurance (UI) wages were reported through KONE Inc.,...

  12. A Kantorovich-Stancu Type Generalization of Szasz Operators including Brenke Type Polynomials

    Directory of Open Access Journals (Sweden)

    Rabia Aktaş

    2013-01-01

    Full Text Available We introduce a Kantorovich-Stancu type modification of a generalization of Szasz operators defined by means of the Brenke type polynomials and obtain approximation properties of these operators. Also, we give a Voronovskaya type theorem for Kantorovich-Stancu type operators including Gould-Hopper polynomials.

  13. 77 FR 27078 - Certain Electronic Devices, Including Mobile Phones and Tablet Computers, and Components Thereof...

    Science.gov (United States)

    2012-05-08

    ...Notice is hereby given that the U.S. International Trade Commission has received a complaint entitled Certain Electronic Devices, Including Mobile Phones and Tablet Computers, and Components Thereof, DN 2896; the Commission is soliciting comments on any public interest issues raised by the complaint or complainant's filing under the Commission's Rules of Practice and...

  14. Morbidity, including fatal morbidity, throughout life in men entering adult life as obese

    DEFF Research Database (Denmark)

    Zimmermann, Esther; Holst, Claus; Sørensen, Thorkild I A

    2011-01-01

    The association between obesity in adults and excess morbidity and mortality is well established, but the health impact throughout adult life of being obese in early adulthood needs elucidation. We investigated somatic morbidity, including fatal morbidity, throughout adulthood in men starting adult...... life as obese....

  15. Selection Component Analysis of Natural Polymorphisms using Population Samples Including Mother-Offspring Combinations, II

    DEFF Research Database (Denmark)

    Jarmer, Hanne Østergaard; Christiansen, Freddy Bugge

    1981-01-01

    Population samples including mother-offspring combinations provide information on the selection components: zygotic selection, sexual selection, gametic seletion and fecundity selection, on the mating pattern, and on the deviation from linkage equilibrium among the loci studied. The theory for the...

  16. Updating RIGs: Including the Systematic Influence of Online Study on Student Evaluation of Teaching

    Science.gov (United States)

    Palmer, Stuart; Smith, Calvin

    2013-01-01

    Based on student evaluation of teaching (SET) ratings from 1,432 units of study over a period of a year, representing 74,490 individual sets of ratings, and including a significant number of units offered in wholly online mode, we confirm the significant influence of class size, year level, and discipline area on at least some SET ratings. We also…

  17. Impact of supersonic and subsonic aircraft on ozone: Including heterogeneous chemical reaction mechanisms

    Science.gov (United States)

    Kinnison, Douglas E.; Wuebbles, Donald J.

    1994-01-01

    Preliminary calculations suggest that heterogeneous reactions are important in calculating the impact on ozone from emissions of trace gases from aircraft fleets. In this study, three heterogeneous chemical processes that occur on background sulfuric acid aerosols are included and their effects on O3, NO(x), Cl(x), HCl, N2O5, ClONO2 are calculated.

  18. Including alternative resources in state renewable portfolio standards: Current design and implementation experience

    International Nuclear Information System (INIS)

    As of October 2012, 29 states, the District of Columbia, and Puerto Rico have instituted a renewable portfolio standard (RPS). Each state policy is unique, varying in percentage targets, timetables, and eligible resources. Increasingly, new RPS polices have included alternative resources. Alternative resources have included energy efficiency, thermal resources, and, to a lesser extent, non-renewables. This paper examines state experience with implementing renewable portfolio standards that include energy efficiency, thermal resources, and non-renewable energy and explores compliance experience, costs, and how states evaluate, measure, and verify energy efficiency and convert thermal energy. It aims to gain insights from the experience of states for possible federal clean energy policy as well as to share experience and lessons for state RPS implementation. - Highlights: • Increasingly, new RPS policies have included alternative resources. • Nearly all states provide a separate tier or cap on the quantity of eligible alternative resources. • Where allowed, non-renewables and energy efficiency are being heavily utilized

  19. Towards optimal education including self-regulated learning in technology-enhanced preschools and primary schools

    NARCIS (Netherlands)

    Mooij, Ton; Dijkstra, Elma; Walraven, Amber; Kirschner, Paul A.

    2014-01-01

    At the start of preschool, four-year-old pupils differ in their development, including the capacity to self-regulate their playing and learning. In preschool and primary school, educational processes are generally adapted to the mean age of the pupils in class. The same may apply to ICT-based pupil-

  20. 77 FR 6463 - Revisions to Labeling Requirements for Blood and Blood Components, Including Source Plasma...

    Science.gov (United States)

    2012-02-08

    ... 20993-0002, (301) 796-9148. SUPPLEMENTARY INFORMATION: In the FR Doc. 2011-33554, appearing on page 7 in the Federal Register of Tuesday, January 3, 2012 (77 FR 7), the following correction is made: 1. On... Requirements for Blood and Blood Components, Including Source Plasma; Correction AGENCY: Food and...

  1. Equations of motion for a rotor blade, including gravity, pitch action and rotor speed variations

    DEFF Research Database (Denmark)

    Kallesøe, Bjarne Skovmose

    2007-01-01

    This paper extends Hodges-Dowell's partial differential equations of blade motion, by including the effects from gravity, pitch action and varying rotor speed. New equations describing the pitch action and rotor speeds are also derived. The physical interpretation of the individual terms in the...

  2. 45 CFR 1308.13 - Eligibility criteria: Visual impairment including blindness.

    Science.gov (United States)

    2010-10-01

    ... blindness. 1308.13 Section 1308.13 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE... impairment including blindness. (a) A child is classified as visually impaired when visual impairment, with.... A child is visually impaired if: (1) The vision loss meets the definition of legal blindness in...

  3. 76 FR 81986 - Honeywell International, Inc., Automation and Control Solutions Division, Including On-Site...

    Science.gov (United States)

    2011-12-29

    ..., 2010 (75 FR 49531). The notice was amended on December 7, 2010 to include several on-site leased worker firms. The amended notice was published in the Federal Register on December 13, 2010 (75 FR 77664-77665... Employment and Training Administration Honeywell International, Inc., Automation and Control...

  4. Including Indigenous Knowledges and Pedagogies in Science-Based Environmental Education Programs

    Science.gov (United States)

    Sutherland, Dawn; Swayze, Natalie

    2012-01-01

    In exploring ways to respectfully include Indigenous Knowledges and pedagogies within environmental education programs, the challenge is to ensure strategies used will meaningfully support learning while reflecting local cultural traditions, languages, beliefs, and perspectives. In this paper, key components for science-based environmental…

  5. AAEC report titles-cumulation 1956-1975 including author and KWIC indexes

    International Nuclear Information System (INIS)

    This publication lists all unclassified technical reports issued by the AAEC Research Establishment since 1956. It supersedes the List of Report Publications dated April 1974 and is the final cumulation of reports published between 1956 and December 1975. Future editions will list reports published from January 1976. An alphabetical author index and a KWIC index to the titles are included. (author)

  6. 76 FR 4724 - Emerson Transportation Division, a Division of Emerson Electric, Including Workers Located...

    Science.gov (United States)

    2011-01-26

    ... Transportation Division, a division of Emerson Electric, Bridgeton, Missouri. The notice was published in the Federal Register on December 16, 2010 (75 FR 75701). At the request of a State of Arkansas agent, the... Division lived throughout the United States, including Arkansas, but report to the Bridgeton,...

  7. 30 CFR 250.527 - What must I include in my casing pressure request?

    Science.gov (United States)

    2010-07-01

    ... following information must be included in the casing pressure request: (a) API number; (b) Lease number; (c... and the calculated daily production rate during last well test (oil, gas, basic sediment, and water... (dry tree, hybrid, or subsea); (n) Date of diagnostic test; (o) Well schematic; (p) Water depth;...

  8. 77 FR 27691 - Oil and Gas; Well Stimulation, Including Hydraulic Fracturing, on Federal and Indian Lands

    Science.gov (United States)

    2012-05-11

    ... practice and American Petroleum Institute (API) recommendations for handling completion fluids (including hydraulic fracturing fluids) (see Section 6.1.6 of API Recommended Practice 51R, Environmental Protection... a growing practice in recent years. Public awareness of fracturing has grown as new...

  9. HERWIG 6 an event generator for Hadron Emission Reactions With Interfering Gluons (including supersymmetric processes)

    CERN Document Server

    Corcella, Gennaro; Marchesini, G; Moretti, S; Odagiri, K; Richardson, Peter; Seymour, Michael H; Webber, Bryan R

    2001-01-01

    HERWIG is a general-purpose Monte Carlo event generator, which includes the simulation of hard lepton-lepton, lepton-hadron and hadron-hadron scattering and soft hadron-hadron collisions in one package. It uses the parton-shower approach for initial- and final-state QCD radiation, including colour coherence effects and azimuthal correlations both within and between jets. This article updates the description of HERWIG published in 1992, emphasising the new features incorporated since then. These include, in particular, the matching of first-order matrix elements with parton showers, a more correct treatment of heavy quark decays, and a wide range of new processes, including many predicted by the Minimal Supersymmetric Standard Model, with the option of R-parity violation. At the same time we offer a brief review of the physics underlying HERWIG together with details of the input and control parameters and the output data, to provide a self-contained guide for prospective users of the program.

  10. 40 CFR 1051.205 - What must I include in my application?

    Science.gov (United States)

    2010-07-01

    ... to provide additional information to evaluate your application. (a) Describe the engine family's specifications and other basic parameters of the vehicle's design and emission controls. List the fuel type on... we specify in 40 CFR part 1065. (h) Identify the engine family's useful life. (i) Include...

  11. 40 CFR 1039.205 - What must I include in my application?

    Science.gov (United States)

    2010-07-01

    .... List the fuel type on which your engines are designed to operate (for example, ultra low-sulfur diesel... your tests were valid under the requirements of this part and 40 CFR part 1065. (2) Report measured CO2... parts of the CFR, and the Clean Air Act. (x) Include good-faith estimates of U.S.-directed...

  12. 40 CFR 1045.205 - What must I include in my application?

    Science.gov (United States)

    2010-07-01

    .... List the fuel type on which your engines are designed to operate (for example, all-season gasoline... parameters on in-use engines to settings outside your intended physically adjustable ranges. (s) Describe how... 40 Protection of Environment 32 2010-07-01 2010-07-01 false What must I include in my...

  13. 21 CFR 200.10 - Contract facilities (including consulting laboratories) utilized as extramural facilities by...

    Science.gov (United States)

    2010-04-01

    ... laboratories) utilized as extramural facilities by pharmaceutical manufacturers. 200.10 Section 200.10 Food and... GENERAL General Provisions § 200.10 Contract facilities (including consulting laboratories) utilized as...) The Food and Drug Administration is aware that many manufacturers of pharmaceutical products...

  14. Membrane for distillation including nanostructures, methods of making membranes, and methods of desalination and separation

    KAUST Repository

    Lai, Zhiping

    2016-01-21

    In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure provide membranes, methods of making the membrane, systems including the membrane, methods of separation, methods of desalination, and the like.

  15. 29 CFR 2570.35 - Information to be included in applications for individual exemptions only.

    Science.gov (United States)

    2010-07-01

    ... exemptions only. 2570.35 Section 2570.35 Labor Regulations Relating to Labor (Continued) EMPLOYEE BENEFITS... be included in applications for individual exemptions only. (a) Except as provided in paragraph (c... consummated or will be consummated only if the exemption is granted; (14) If the exemption transaction...

  16. 76 FR 34271 - Hewlett Packard, Global Parts Supply Chain, Global Product Life Cycles Management Unit, Including...

    Science.gov (United States)

    2011-06-13

    ... workers of Hewlett Packard, Global Parts Supply Chain, Global Product Life Cycles Management Unit... Employment and Training Administration Hewlett Packard, Global Parts Supply Chain, Global Product Life Cycles... Supply Chain Group, including leased workers from QFlex, North America Logistics and UPS...

  17. Sensorless Speed Control including zero speed of Non Salient PM Synchronous Drives

    DEFF Research Database (Denmark)

    Rasmussen, Henrik

    2005-01-01

    including the rotor speed. Assuming motor parameters known the design achieves stability with guaranteed region of attraction even at zero speed. The control method is made robust at zero and low speed by changing the direct vector current component to a value different from zero. In order to verify the...

  18. Global simulations of Minkowski space-time including space-like infinity

    CERN Document Server

    Doulis, Georgios

    2016-01-01

    In this work, we study linearised gravitational fields on the entire Minkowski space-time including space-like infinity. The generalised conformal field equations linearised about a Minkowski background are utilised for this purpose. In principle, this conformal representation of Einstein's equations can be used to carry out global simulations of Minkowski space-time. We investigate thoroughly this possibility.

  19. Optimal design of power system stabilizer for power systems including doubly fed induction generator wind turbines

    International Nuclear Information System (INIS)

    This paper presents an evolutionary algorithm-based approach for optimal design of power system stabilizer (PSS) for multi-machine power systems that include doubly fed induction generator wind turbines. The proposed evolutionary algorithm is an improved particle swarm optimization named chaotic particle swarm optimization with passive congregation (CPSO-PC) applied for finding the optimal settings of PSS parameters. Two different eigenvalue-based objectives are combined as the objective function for the optimization problem of tuning PSS parameters. The first objective function comprises the damping factor of lightly damped electro-mechanical modes and the second one includes the damping ratio of these modes. The effectiveness of the proposed method to design PSS for the power systems including DFIG (Doubly Fed Induction Generator) is extensively demonstrated through eigenvalue analysis and time-domain simulations and also by comparing its simulation results with the results of other heuristic optimization approaches. - Highlights: • A new optimization model for design of PSS in power systems including DFIG is proposed. • A detailed and realistic modeling of DFIG is presented. • A new evolutionary algorithm is suggested for solving the optimization problem of designing PSS

  20. 21 CFR 111.210 - What must the master manufacturing record include?

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What must the master manufacturing record include... SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION CURRENT GOOD MANUFACTURING PRACTICE IN MANUFACTURING...: Requirements for the Master Manufacturing Record § 111.210 What must the master manufacturing record...

  1. Including Adulthood in Music Education Perspectives and Policy: A Lifespan View

    Science.gov (United States)

    Myers, David E.

    2012-01-01

    Music learning among adults is witnessing rapid escalation as an important area of research and practice among music education professionals. In contrast to the years encompassed by childhood and adolescence, a significant challenge in teaching adults is that average life expectancies in developed countries include some 55 to 65 years beyond age…

  2. 75 FR 34172 - Lordstown Seating Systems, a Subsidiary of Magna Seating, Including Workers Whose Unemployment...

    Science.gov (United States)

    2010-06-16

    ... notice was published in the Federal Register on May 5, 2010 (75 FR 24751). At the request of the state... Employment and Training Administration Lordstown Seating Systems, a Subsidiary of Magna Seating, Including Workers Whose Unemployment Insurance (UI) Wages Are Reported Through Intier Automotive Seatings of...

  3. Including dietary fiber and resistant starch to increase satiety and reduce aggression in gestating sows

    Science.gov (United States)

    The swine industry is under a great deal of pressure to return sows to group housing. However, aggression during mixing of pregnant sows impacts sow welfare and productivity. The aim of this study was to increase satiety and reduce aggression by including dietary fiber and fermentable carbohydrate. ...

  4. Tornadoes: Nature's Most Violent Storms. A Preparedness Guide Including Safety Information for Schools.

    Science.gov (United States)

    American National Red Cross, Washington, DC.

    This preparedness guide explains and describes tornadoes, and includes safety information for schools. A tornado is defined as a violently rotating column of air extending from a thunderstorm to the ground. The guide explains the cause of tornadoes, provides diagrams of how they form, describes variations of tornadoes, and classifies tornadoes by…

  5. 78 FR 8587 - Thomson Reuters, Finance Operations & Technology Division, Including On-Site Leased Workers From...

    Science.gov (United States)

    2013-02-06

    ... was published in the Federal Register on August 16, 2012 (77 FR 49459). At the request of the State... Employment and Training Administration Thomson Reuters, Finance Operations & Technology Division, Including... Worker Adjustment Assistance on August 2, 2012, applicable to workers of Thomson Reuters,...

  6. 27 CFR 53.91 - Charges to be included in sale price.

    Science.gov (United States)

    2010-04-01

    ... or display of the article, for sales promotion programs, or otherwise. With respect to the rules... sale price. 53.91 Section 53.91 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND... AMMUNITION Special Provisions Applicable to Manufacturers Taxes § 53.91 Charges to be included in sale...

  7. 78 FR 12358 - UBS Financial Services, Inc., Wealth Management Americas Operations, Including On-Site Leased...

    Science.gov (United States)

    2013-02-22

    ... Employment and Training Administration UBS Financial Services, Inc., Wealth Management Americas Operations..., applicable to workers of UBS Financial Services, Inc., Wealth Management Americas Operations (UBS), Weehawken... Department's certification is to include all leased workers on-site at UBS Financial Services, Inc.,...

  8. 75 FR 47631 - Douglas Battery Manufacturing Co., Currently Known as Lexington Road Properties, Inc., Including...

    Science.gov (United States)

    2010-08-06

    ... notice was published in the Federal Register February 16, 2010 (75 FR 7036). At the request of the State... Employment and Training Administration Douglas Battery Manufacturing Co., Currently Known as Lexington Road... January 6, 2010, applicable to workers of Douglas Battery Manufacturing Co., including on-site...

  9. 26 CFR 1.856-0 - Revenue Act of 1978 amendments not included.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 9 2010-04-01 2010-04-01 false Revenue Act of 1978 amendments not included. 1.856-0 Section 1.856-0 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Real Estate Investment Trusts § 1.856-0 Revenue Act of...

  10. 15 CFR 9.3 - Appliances and equipment included in program.

    Science.gov (United States)

    2010-01-01

    ..., clothes dryers, kitchen ranges and ovens, water heaters, comfort heating equipment, and television... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Appliances and equipment included in... VOLUNTARY LABELING PROGRAM FOR HOUSEHOLD APPLIANCES AND EQUIPMENT TO EFFECT ENERGY CONSERVATION §...

  11. 33 CFR 148.105 - What must I include in my application?

    Science.gov (United States)

    2010-07-01

    ... the cost of removing all of the deepwater port marine components, including pipelines that lie beneath..., for night detection. (r) Information on dedicated fixed offshore components. (1) A description and... measuring, leak detection, emergency shutdown, and the alarm system. (7) The personnel capacity of...

  12. 76 FR 24051 - In the Matter of Certain Electronic Devices, Including Mobile Phones, Mobile Tablets, Portable...

    Science.gov (United States)

    2011-04-29

    ... Music Players, and Computers, and Components Thereof; Notice of Institution of Investigation AGENCY: U.S... tablets, portable music players, and computers, and components thereof by reason of infringement of... importation of certain electronic devices, including mobile phones, mobile tablets, portable music...

  13. 75 FR 10317 - DHL Global Forwarding, A Subsidiary of DP DHL, Finance and Accounting Divisions, Including...

    Science.gov (United States)

    2010-03-05

    ... (TA-W-70,857D). The notice was published in the Federal Register on February 16, 2010 (75 FR 7033-7034... Employment and Training Administration DHL Global Forwarding, A Subsidiary of DP DHL, Finance and Accounting... Global Forwarding, A Subsidiary of DP DHL, Finance and Accounting Divisions, Including Workers...

  14. Including Adults with Intellectual Disabilities in Research: Scientists' Perceptions of Risks and Protections

    Science.gov (United States)

    McDonald, Katherine E.; Kidney, Colleen A.; Nelms, Sandra L.; Parker, Michael R.; Kimmel, Ali; Keys, Christopher B.

    2009-01-01

    Social and cognitive characteristics of adults with intellectual disabilities (ID) place them at risk for inappropriate inclusion in or exclusion from research participation. As we grapple with how to include adults with ID in research in order to secure their right to contribute to scientific advancements and be positioned to derive benefit from…

  15. 42 CFR 137.329 - What environmental considerations must be included in the construction project agreement?

    Science.gov (United States)

    2010-10-01

    ... in the construction project agreement? 137.329 Section 137.329 Public Health PUBLIC HEALTH SERVICE... SELF-GOVERNANCE Construction Project Assumption Process § 137.329 What environmental considerations must be included in the construction project agreement? The construction project agreement must...

  16. 40 CFR 725.155 - Information to be included in the MCAN.

    Science.gov (United States)

    2010-07-01

    ... SUBSTANCES CONTROL ACT REPORTING REQUIREMENTS AND REVIEW PROCESSES FOR MICROORGANISMS Microbial Commercial... estimate may be by weight or volume and should include an estimation of viability (i.e., viable cells per... commercial or consumer use. (h) Worker exposure and environmental release. (1) For sites controlled by...

  17. Solar Energy Education. Industrial arts: teacher's guide. Field test edition. [Includes glossary

    Energy Technology Data Exchange (ETDEWEB)

    1981-05-01

    An instructional aid is presented which integrates the subject of solar energy into the classroom study of industrial arts. This guide for teachers was produced in addition to the student activities book for industrial arts by the USDOE Solar Energy Education. A glossary of solar energy terms is included. (BCS)

  18. 78 FR 49764 - Certain Portable Electronic Communications Devices, Including Mobile Phones and Components...

    Science.gov (United States)

    2013-08-15

    ... `650 patent''); and 8,363,824. 78 FR 38362 (Jun. 26, 2013). The respondents are HTC Corporation of... COMMISSION Certain Portable Electronic Communications Devices, Including Mobile Phones and Components Thereof... server at http://www.usitc.gov . The public record for this investigation may be viewed on the...

  19. Furan and Alkylated Furans in Heat Processed Food, Including Home Cooked Products

    DEFF Research Database (Denmark)

    Fromberg, Arvid; Mariotti, Maria S.; Pedreschi, Franco;

    2014-01-01

    carbohydrates. Interestingly, breakfast cereals, dry bread products, and dried fruit products including raisins, plums and bananas contained furan at levels up to 387 mu g/kg. Furan was also found in the dry ingredients of cookies and bread, and in snacks such as crisps and popcorn. The 2-alkylfurans, 2...

  20. Cost and benefit including value of life, health and environmental damage measured in time units

    DEFF Research Database (Denmark)

    Ditlevsen, Ove Dalager; Friis-Hansen, Peter

    2009-01-01

    Key elements of the authors' work on money equivalent time allocation to costs and benefits in risk analysis are put together as an entity. This includes the data supported dimensionless analysis of an equilibrium relation between total population work time and gross domestic product leading to t...

  1. A revision of the genus Osmoxylon (Araliaceae) in Palau, including two new species.

    Science.gov (United States)

    Costion, Craig M; Plunkett, Gregory M

    2016-01-01

    Osmoxylon Miq. (Araliaceae) is revised for Palau, Micronesia including descriptions of two new taxa Osmoxylon leidichii Costion, sp. nov. and Osmoxylon ngardokense Costion, sp. nov. Full descriptions are provided for all four Palau species, along with diagnostic field keys. PMID:26884705

  2. Thermoelectric material including conformal oxide layers and method of making the same using atomic layer deposition

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Jung Young; Ahn, Dongjoon; Salvador, James R.; Meisner, Gregory P.

    2016-06-07

    A thermoelectric material includes a substrate particle and a plurality of conformal oxide layers formed on the substrate particle. The plurality of conformal oxide layers has a total oxide layer thickness ranging from about 2 nm to about 20 nm. The thermoelectric material excludes oxide nanoparticles. A method of making the thermoelectric material is also disclosed herein.

  3. 78 FR 18457 - Definition of Form I-94 To Include Electronic Format

    Science.gov (United States)

    2013-03-27

    ... statistical purposes, including use by the DOC Office of Travel and Tourism Industries to collect monthly... Tourism Organization recommendation for reporting arrivals to all countries. Current Paper Form I-94...-94 at Airports and Seaports The Form I-94 was established prior to advances in technology and...

  4. 12 CFR 516.20 - What information must I include in my draft business plan?

    Science.gov (United States)

    2010-01-01

    ... business plan? 516.20 Section 516.20 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE... What information must I include in my draft business plan? If you must submit a draft business plan... described in the savings association's draft business plan; and (d) Demonstrate how applicable...

  5. 78 FR 56737 - Certain Portable Electronic Communications Devices, Including Mobile Phones and Components...

    Science.gov (United States)

    2013-09-13

    ... `211 patent''); 7,187,945; 8,140,650 (``the `650 patent''); and 8,363,824. 78 FR 38362 (Jun. 26, 2013... investigation with respect to three of the six patents, namely the `189, `211 and `650 patents. 78 FR 49764 (Aug... COMMISSION Certain Portable Electronic Communications Devices, Including Mobile Phones and Components...

  6. 31 CFR 20.215 - What must I include in my drug-free awareness program?

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false What must I include in my drug-free awareness program? 20.215 Section 20.215 Money and Finance: Treasury Office of the Secretary of the Treasury...-free awareness program to inform employees about— (a) The dangers of drug abuse in the workplace;...

  7. Comparison of different methods to include recycling in LCAs of aluminium cans and disposable polystyrene cups

    NARCIS (Netherlands)

    Harst-Wintraecken, van der Eugenie; Potting, José; Kroeze, Carolien

    2016-01-01

    Many methods have been reported and used to include recycling in life cycle assessments (LCAs). This paper evaluates six widely used methods: three substitution methods (i.e. substitution based on equal quality, a correction factor, and alternative material), allocation based on the number of rec

  8. Modification of TOUGH2 to Include the Dusty Gas Model for Gas Diffusion; TOPICAL

    International Nuclear Information System (INIS)

    The GEO-SEQ Project is investigating methods for geological sequestration of CO(sub 2). This project, which is directed by LBNL and includes a number of other industrial, university, and national laboratory partners, is evaluating computer simulation methods including TOUGH2 for this problem. The TOUGH2 code, which is a widely used code for flow and transport in porous and fractured media, includes simplified methods for gas diffusion based on a direct application of Fick's law. As shown by Webb (1998) and others, the Dusty Gas Model (DGM) is better than Fick's Law for modeling gas-phase diffusion in porous media. In order to improve gas-phase diffusion modeling for the GEO-SEQ Project, the EOS7R module in the TOUGH2 code has been modified to include the Dusty Gas Model as documented in this report. In addition, the liquid diffusion model has been changed from a mass-based formulation to a mole-based model. Modifications for separate and coupled diffusion in the gas and liquid phases have also been completed. The results from the DGM are compared to the Fick's law behavior for TCE and PCE diffusion across a capillary fringe. The differences are small due to the relatively high permeability (k= 10(sup -11) m(sup 2)) of the problem and the small mole fraction of the gases. Additional comparisons for lower permeabilities and higher mole fractions may be useful

  9. 78 FR 26847 - Including Specific Pavement Types in Federal-aid Highway Traffic Noise Analyses

    Science.gov (United States)

    2013-05-08

    ... Federal Highway Administration Including Specific Pavement Types in Federal-aid Highway Traffic Noise... types used in Federal-aid highway traffic noise analyses. Current highway traffic noise analyses rely on... (OGAC), and Portland cement concrete (PCC). Prediction of future noise levels is based on the...

  10. 34 CFR 366.43 - What must be included in the Director's final written decision?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false What must be included in the Director's final written decision? 366.43 Section 366.43 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION CENTERS...

  11. 34 CFR 86.100 - What must the IHE's drug prevention program include?

    Science.gov (United States)

    2010-07-01

    ... in writing to each employee, and to each student who is taking one or more classes for any type of academic credit except for continuing education units, regardless of the length of the student's program of... those sanctions, up to and including expulsion or termination of employment and referral for...

  12. Including Antenna Models in Microwave Imaging for Breast-Cancer Screening

    DEFF Research Database (Denmark)

    Rubæk, Tonny; Meincke, Peter

    2006-01-01

    Microwave imaging is emerging as a tool for screening for breast cancer, but the lack of methods for including the characteristics of the antennas of the imaging systems in the imaging algorithms limits their performance. In this paper, a method for incorporating the full antenna characteristics...

  13. Pilot's Guide to an Airline Career, Including Sample Pre-Employment Tests.

    Science.gov (United States)

    Traylor, W.L.

    Occupational information for persons considering a career as an airline pilot includes a detailed description of the pilot's duties and material concerning preparation for occupational entry and determining the relative merits of available jobs. The book consists of four parts: Part I, The Job, provides an overview of a pilot's duties in his daily…

  14. 76 FR 76434 - Certain Integrated Circuits, Chipsets, and Products Containing Same Including Televisions...

    Science.gov (United States)

    2011-12-07

    ...Notice is hereby given that the U.S. International Trade Commission has received a complaint entitled In Re Certain Integrated Circuits, Chipsets, And Products Containing Same including Televisions, DN 2860; the Commission is soliciting comments on any public interest issues raised by the...

  15. Three- and Four-Body Scattering Calculations including the Coulomb Force

    OpenAIRE

    Deltuva, A

    2009-01-01

    The method of screening and renormalization for including the Coulomb interaction in the framework of momentum-space integral equations is applied to the three- and four-body nuclear reactions. The Coulomb effect on the observables and the ability of the present nuclear potential models to describe the experimental data is discussed.

  16. 20 CFR 410.410 - Total disability due to pneumoconiosis, including statutory presumption.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Total disability due to pneumoconiosis... Death Due to Pneumoconiosis § 410.410 Total disability due to pneumoconiosis, including statutory... pneumoconiosis arising out of employment in one or more of the Nation's coal mines,” and to the...

  17. 20 CFR 410.416 - Determining origin of pneumoconiosis, including statutory presumption.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Determining origin of pneumoconiosis... Death Due to Pneumoconiosis § 410.416 Determining origin of pneumoconiosis, including statutory... suffered from pneumoconiosis, it will be presumed, in the absence of persuasive evidence to the...

  18. Modification of a fire drought index for tropical wetland ecosystems by including water table depth

    NARCIS (Netherlands)

    Taufik, Muh; Setiawan, B.I.; Lanen, van H.A.J.

    2015-01-01

    In this paper, we discuss how an existing empirical drought index, i.e. the Keetch-Byram Drought Index (KBDI) that is commonly used for assessing forest fire danger, has been adjusted and modified for improved use in tropical wetland ecosystems. The improvement included: (i) adjustment of the dro

  19. 30 CFR 285.810 - What must I include in my Safety Management System?

    Science.gov (United States)

    2010-07-01

    ... System? 285.810 Section 285.810 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR..., COPs and GAPs Safety Management Systems § 285.810 What must I include in my Safety Management System? You must submit a description of the Safety Management System you will use with your COP...

  20. 29 CFR 780.116 - Commodities included by reference to the Agricultural Marketing Act.

    Science.gov (United States)

    2010-07-01

    ... Marketing Act. 780.116 Section 780.116 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR... Commodities § 780.116 Commodities included by reference to the Agricultural Marketing Act. (a) Section 3(f... defined as agricultural commodities in section 15(g) of the Agricultural Marketing Act, as amended (12...