WorldWideScience

Sample records for blandt patienter med

  1. Kronisk iskaemisk hjerteinsufficiens. Revaskularisering bedrer overlevelsen blandt patienter med hibernating myocardium

    DEFF Research Database (Denmark)

    Holdgaard, Paw Chr; Nielsen, Søren Steen; Wiggers, Henrik

    2007-01-01

    imaging was performed with 99mTc-sestamibi and glucose metabolism was visualized with 18F-fluorodeoxyglucose (18F-FDG) gamma camera PET. Medical records and death certificate were reviewed retrospectively. RESULTS: 50 patients were included. We found an increased survival among patients with HIB who......INTRODUCTION: Patients with ischemic heart failure and reversible dysfunctional myocardium (Hibernating myocardium, HIB) can benefit from revascularization. These patients can be selected with nuclear methods. The purpose of this study was to describe the results of the imaging procedures...... in patients tested for HIB and relate the results to the choice of treatment and cause of death. MATERIALS AND METHODS: During a 2-year period 51 patients were referred to determine the amount of HIB. This can be determined with blood flow and metabolic imaging of the heart. Resting-myocardial perfusion...

  2. En undersøgelse af livshistorier blandt patienter med skizofreni. (An examination of life stories among patients with schizophrenia)

    DEFF Research Database (Denmark)

    Holm, Tine; Bliksted, Vibeke Fuglsang; Thomsen, Dorthe Kirkegaard

    have less coherent life stories compared to healthy controls. 30 patients and 30 matched controls describe and rate up to 10 life story chapters and 3 self-defining memories (SDMs). We expect that patients will have less chronologically organized chapters and that they will rate degree of self......-continuity and causal coherence lower for both SDMs and life story chapters....

  3. En undersøgelse af livshistorier blandt patienter med skizofreni. (An examination of life stories among patients with schizophrenia)

    DEFF Research Database (Denmark)

    Holm, Tine; Bliksted, Vibeke Fuglsang; Thomsen, Dorthe Kirkegaard

    Lack of self-continuity is a defining feature in schizophrenia, which involves the experience that the past self is not meaningfully connected to the present self. Self-continuity may be established through the life story. In this study-in-progress we examine whether patients with schizophrenia...... have less coherent life stories compared to healthy controls. 30 patients and 30 matched controls describe and rate up to 10 life story chapters and 3 self-defining memories (SDMs). We expect that patients will have less chronologically organized chapters and that they will rate degree of self......-continuity and causal coherence lower for both SDMs and life story chapters....

  4. Reduktion af stress og sygefravær blandt patienter med arbejdsrelaterede belastnings- og tilpasningsreaktioner henvist til Arbejdsmedicinsk klinik

    DEFF Research Database (Denmark)

    Glasscock, David John; Carstensen, Ole; Dalgaard, Vita Ligaya Ponce

    is plagued by a number of methodological limitations. The definition of study populations is often unclear and there is a lack of studies with patients that have a clinically documented need for treatment. There is also a lack of research that evaluates interventions aimed at both the individual patient...... reactions to stress or adjustment disorders that were work related, patients were offered participation in the project, if inclusion and exclusion criteria were satisfied. Patients answered baseline questionnaires prior to initial examination. The questionnaire, which was used to measure treatment effects......, was repeated again 4 and 10 months after inclusion. Treatment effects were assessed with validated scales: Perceived stress (PSS-10), mental health (GHQ-30), sleep quality (selected items from the BNSQ), and cognitive functioning (two subscales from the CFQ). There were also items concerning sick-leave. After...

  5. Cancer blandt gigtpatienter behandlet med tumornekrosefaktor-alfa-haemmere

    DEFF Research Database (Denmark)

    Dreyer, Lene; Mellemkjaer, Lene; Hetland, Merete Lund

    2009-01-01

    INTRODUCTION: The use of anti-tumour necrosis factor (anti-TNF) therapy is increasing in the treatment of rheumatoid arthritis (RA), spondyloarthropathy, psoriasis and inflammatory bowel disease. It is being debated whether treatment of patients with rheumatic diseases with anti-TNF therapy...... is associated with an increased cancer incidence. MATERIAL AND METHODS: A descriptive study of cancer cases among 3,688 patients with rheumatic diseases who received anti-TNF therapy was performed. The patients were identified in the nationwide database DANBIO and had a total number of treatment years of 6......,092 years. All cancer cases were identified and the cancer diagnoses were subsequently confirmed by medical record review. RESULTS: A total of 30 cancers in 28 of 3,688 patients were registered in the DANBIO after initiation of anti-TNF therapy in the period from October 2000 to June 2007. Among these six...

  6. Cancer blandt gigtpatienter behandlet med tumornekrosefaktor-alfa-haemmere

    DEFF Research Database (Denmark)

    Dreyer, Lene; Mellemkjaer, Lene; Hetland, Merete Lund

    2009-01-01

    %). CONCLUSION: In our descriptive study from the nationwide database DANBIO, a total of 30 cancers were observed in 3,688 patients with rheumatic diseases within a cumulated period of treatment with anti-TNF of 6,092 years. Follow-up for anti-rheumatic and adverse effects in patients in the DANBIO database...... is associated with an increased cancer incidence. MATERIAL AND METHODS: A descriptive study of cancer cases among 3,688 patients with rheumatic diseases who received anti-TNF therapy was performed. The patients were identified in the nationwide database DANBIO and had a total number of treatment years of 6...... men and 20 women had RA, and two men had Morbus Becterew. The following cancer types were observed: malignant lymphoma 2 (7%), lung 4 (13%), plicae vocalis 2 (7%), breast 4 (13%), pancreatic 3 (10%), colorectal 2 (7%), prostate 1 (3%), malignant melanoma 3 (10%) and non-melanoma skin cancer 9 (30...

  7. Cancer blandt gigtpatienter behandlet med tumornekrosefaktor-alfa-haemmere

    DEFF Research Database (Denmark)

    Dreyer, Lene; Mellemkjaer, Lene; Hetland, Merete Lund

    2009-01-01

    The use of anti-tumour necrosis factor (anti-TNF) therapy is increasing in the treatment of rheumatoid arthritis (RA), spondyloarthropathy, psoriasis and inflammatory bowel disease. It is being debated whether treatment of patients with rheumatic diseases with anti-TNF therapy is associated...... with an increased cancer incidence....

  8. Høj selvmordsrisiko blandt psykiatriske patienter

    DEFF Research Database (Denmark)

    Nordentoft, Merete; Madsen, Trine

    2011-01-01

    Suicide rates in Denmark have declined since 1980 both in the general population and among psychiatric patients. In recent years, the number of suicides in Denmark has been rather stable with approximately 650 incidents each year. Register-based studies indicate that half of those who commit suic...... patients is previous suicide attempt. A crisis plan developed together with the patient can be helpful. Regular screening for risk of suicide should be implemented in psychiatric services....

  9. Høj selvmordsrisiko blandt psykiatriske patienter

    DEFF Research Database (Denmark)

    Nordentoft, Merete; Madsen, Trine

    2011-01-01

    Suicide rates in Denmark have declined since 1980 both in the general population and among psychiatric patients. In recent years, the number of suicides in Denmark has been rather stable with approximately 650 incidents each year. Register-based studies indicate that half of those who commit...... suicide have had at least one psychiatric admission in the past, and the risk of suicide is approximately twentyfold increased in psychiatric patients compared to the risk in the general population with only a modest variation across diagnoses. The most important risk factor for suicide among psychiatric...... patients is previous suicide attempt. A crisis plan developed together with the patient can be helpful. Regular screening for risk of suicide should be implemented in psychiatric services....

  10. Mikroalbuminuri er associeret med firedobbelt risiko for iskaemisk hjertesygdom blandt hypertensive

    DEFF Research Database (Denmark)

    Jensen, Jan Skov; Feldt-Rasmussen, Bo F; Strandgaard, Svend

    2002-01-01

    INTRODUCTION: The urinary excretion of albumin is positively correlated to the presence of ischaemic heart disease and atherosclerotic risk factors in subjects with arterial hypertension. The aim of this population-based, follow-up study of hypertensive patients was to assess the predictive impact...... in the hypertension clinic, and rigorous control of blood pressure and other modifiable atherosclerotic risk factors is to be recommended in hypertensive patients with microalbuminuria....... in a population of 2085 men and women aged 30-60 years. Exclusion criteria were ischaemic heart disease, diabetes mellitus, and renal or urinary tract disease. Untreated hypertension or borderline hypertension (a systolic blood pressure above 140 mmHg and/or a diastolic blood pressure above 90 mmHg) were found...

  11. Levetiden blandt personer med og uden hiv-infektion i Danmark 1995-2005

    DEFF Research Database (Denmark)

    Lohse, Nicolai; Hansen, Ann-Brit Eg; Pedersen, Gitte

    2007-01-01

    It has been difficult to measure the median survival of HIV-infected patients by comparing selected HIV samples and control groups. Data from the Danish HIV Cohort Study combined with the Central Registration System has made it possible to accurately compare the survival of HIV-infected persons...... and uninfected persons. In 2000 to 2005, the median remaining lifetime at age 25 years in the general population was 51 years and 39 years for HIV-infected persons without hepatitis C virus infection. In conclusion, persons with HIV infection have a good, albeit far from normal, life expectancy. Udgivelsesdato...

  12. Personalets deltagelse i forebyggelse blandt voksne patienter i almen laegepraksis

    DEFF Research Database (Denmark)

    Hansen, Dorte Gilså; K. Rasmussen, Niels; Munck, Anders P

    2008-01-01

    INTRODUCTION: Prevention of lifestyle-related diseases and related complications represent an increasing part of daily work in general practice. In relation to selected doctor and patient characteristics we analyzed 1) the practice staff's current involvement in preventive measures, and 2......) the doctors' wishes for increased involvement. MATERIALS AND METHODS: In total, 378 out of 381 general practitioners from ten counties participating in "Audit on prevention in general practice 2004" filled in a two-page questionnaire. RESULTS: Almost all (377/378) had staff employed. More than half...... of the doctors stated that the staff performed tasks in connection with weight control, vaccination of adults, blood pressure checks, lung function tests, alcohol abuse treatment and dietary counselling. A total of 72% of the doctors wished for greater staff involvement within one or more areas, especially...

  13. Implementering af ny standard for forebyggelse af delir i forhold til ældre svagelige patienter > 65 år med hoftefraktur

    DEFF Research Database (Denmark)

    Bagger, Bettan; Rehder, Bente; Pedersen, Niels

    2013-01-01

    Baggrund: Pro-hip er et inter-regionalt projekt www.prohip.eu der blandt andet har til formål at evidensbasere den rehabiliterende sygepleje til hoftepatienten i forhold til indsatsområderne; ernæring, urinretention/UVI, delir og tryksår. Delirium er et hyppigt forekommende problem blandt patienter...... standard. Intentionen er således at udvikle en evidensbaseret standard eller instruks, der har til formål at opspore tidlige symptomer på konfusion og dermed forebygge udviklingen af deliriøs tilstand hos patienten med hoftefraktur. Metode: Der er udarbejdet et systematisk review med henblik på...

  14. Med troen som fællesnævner – fællesskab blandt unge i Indre Mission

    Directory of Open Access Journals (Sweden)

    Tina Wilchen Christensen

    2010-12-01

    Full Text Available Artiklen vil belyse de mekanismer, der ligger til grund for et velfungerende fællesskab i en af Indre Missions ungdomsforeninger i Århus. Troen har på forskellige måder en central position i fællesskabet, og denne artikel vil argumentere for de unges tro som en social identitet, idet deres habitus synes at have en afgørende betydning for den og deres oplevelse af det religiøst funderede fællesskab. Artiklenvil også belyse, hvordan Biblen og dens fortællinger udgør den fortolkningsramme, som de unge er opvokset med og forstår livet igennem. Artiklen viser desuden den rolle, det kollektive samvær spiller i de unges konstruktion af Gud og egen identitet som kristen.Faith as common ground- community feeling among young evangelicals in DenmarkThe aim of this article is to demonstrate the mechanisms that underlie a youth association in the so-called Home Mission, a branch of the Evangelical Lutheran Church of Denmark. It is the result of anthropological research focusing on the sense of community among members aged between 15 and 27. In a number of ways faith plays a central role in the community, and the main argument of the article is that the young people's faith constitutes a social identity, since their habitus seems to have a decisive impact on their experience of the faith-based community. The article further demonstrates how the Bible and its narratives form the framework of interpretation with which the young people have grown up, and which, in their present life as adults, continues to mould their understanding and view of life, as well as the role that collective interaction plays in the young people's construction of God and their own identity as Christians. A core argument in the article is that faith is a socialization into a structure which results in all participants having the same frame of reference and therefore experiencing a strong feeling of community with one another within this particular wing of the Church

  15. Wind interviewet til Berlingske om den stigningen opbakning til EU blandt danskerne

    DEFF Research Database (Denmark)

    Wind, Marlene

    2017-01-01

    Professor og centerleder, Marlene Wind, var tirsdag den 11. juli interviewet til Berlingske om den stigende opbakning til EU blandt danskerne. Wind forklarer blandt andet stigningen med de igangværende Brexit forhandlinger, men også at truslen fra Rusland er med til at forstærke opbakningen til EU...

  16. Dødelighed--selvmord og naturlig død--blandt deprimerede patienter. Relationen til depressionstype

    DEFF Research Database (Denmark)

    Hansen, P E; Wang, A G; Kragh-Sørensen, P

    1994-01-01

    . The observed mortality was significantly greater than that expected. The increased mortality was essentially due to suicides and mainly found among women. Patients scored as being nonendogenously depressed had a significantly higher suicide rate than endogenously depressed patients. The excess number......A total of 219 inpatients with a DSM-III diagnosis of major depression, (150 women and 69 men), were followed prospectively for three to ten years and mortality was recorded. The patients were previous participants in psychopharmacological multicentre trials, which were carried out for the purpose...... of comparing the antidepressant effect of newer selective serotonin reuptake inhibitors (SSRI), citalopram and paroxetine, with that of the tricyclic antidepressant drug, clomipramine. Diagnostic classification according to the Newcastle-I Scale into endogenous and nonendogenous depression was performed...

  17. Pause med trombocytaggregationshaemmere hos kirurgiske patienter med kardiel stent

    DEFF Research Database (Denmark)

    Johansen, Mathias; Afshari, Arash; Kristensen, Billy

    2010-01-01

    Dual antiplatelet therapy with aspirin and clopidogrel is increasingly used for secondary prevention of cardiovascular events in patients with percutaneous coronary intervention. Anesthesiologists and surgeons are faced with the challenge of managing these patients prior to a surgical procedure...

  18. Risikostratificering af patienter med diabetes mellitus

    DEFF Research Database (Denmark)

    Qvist, Peter; Glintborg, Dorte; Andries, Alin

    2008-01-01

    with diabetes mellitus. MATERIAL AND METHODS: We included patients with diabetes from the catchment areas of four diabetes out-patient clinics in southern Denmark. Patients were risk-stratified to 3 follow-up levels (level 1 - follow-up only by their GP, level 2 - intensified follow-up by GP and/or shared care...... schemes, level 3 - follow-up only in out-patient clinics). The results were subsequently compared with the patients' actual follow-up status. RESULTS: A total of 647 patients (563 type 2 diabetes and 84 type 1 diabetes) were included from 15 GPs. Among these, 139 were stratified to level 1, 409 to level 2...

  19. Fod- og ankeltraume hos patient med diabetes

    DEFF Research Database (Denmark)

    Falborg, Bettina; Ebskov, Lars

    2009-01-01

    If confronted with a neuropathic patient with an acute foot-ankle trauma, including fracture, this patient is by definition Eichenholtz stage 0. This is of major importance for the treatment. Whereas the surgical handling of fractures does not differ from ordinary fracture treatment, the subsequent...

  20. Muskelstyrken hos patienter med fibromyalgi. Et litteraturstudie

    DEFF Research Database (Denmark)

    Dombernowsky, Tilde; Dreyer, Lene; Bartels, Else Marie

    2008-01-01

    Do patients with fibromyalgia (FM) have reduced muscular strength? We examined 22 articles and conclude from the results of these that FM patients have reduced muscular strength in their hands and quadriceps. The material also suggests generalised reduced muscular strength. However, the studies...

  1. Immunmedieret perikarditis hos patient med meningokokmeningitis

    DEFF Research Database (Denmark)

    Fuglsang Hansen, Janne; Johansen, Isik Somuncu

    2014-01-01

    Extrameningial manifestations in patients with meningococcal meningitis are rare. One of these manifestations is immune-mediated or purulent pericarditis. We present a case where a patient with meningococcal meningitis developed pericarditis on the 11th day after admission. A pericardial puncture...

  2. Ventrikulaere takyarytmier hos patienter med kardiomyopati

    DEFF Research Database (Denmark)

    Henningsen, Kristoffer; Christensen, Alex Hørby; Svendsen, Jesper Hastrup

    2008-01-01

    INTRODUCTION: The purpose of this study was to determine the number and distribution of cardiomyopathies as the aetiology of ventricular tachyarrhythmias among patients discharged from the Department of Cardiology, Rigshospitalet. MATERIALS AND METHODS: The study was a retrospective review......), 57 (45%) patients had arrhythmogenic right ventricular cardiomyopathy (ARVC) and 13 (10%) had hypertrophic cardiomyopathy (HCM). The average age was 44 years for HCM, 41 years for ARVC and 58 years for DCM. The majority of the patients were male. ICD treatment was used in 95% of the patients...... cardiology department. Implantation of an ICD device has a central position in the treatment of patients with cardiomyopathy and ventricular tachyarrythmias and is primarily used as a prophylactic treatment....

  3. Ventrikulaere takyarytmier hos patienter med kardiomyopati

    DEFF Research Database (Denmark)

    Henningsen, Kristoffer; Christensen, Alex Hørby; Svendsen, Jesper Hastrup

    2008-01-01

    INTRODUCTION: The purpose of this study was to determine the number and distribution of cardiomyopathies as the aetiology of ventricular tachyarrhythmias among patients discharged from the Department of Cardiology, Rigshospitalet. MATERIALS AND METHODS: The study was a retrospective review......), 57 (45%) patients had arrhythmogenic right ventricular cardiomyopathy (ARVC) and 13 (10%) had hypertrophic cardiomyopathy (HCM). The average age was 44 years for HCM, 41 years for ARVC and 58 years for DCM. The majority of the patients were male. ICD treatment was used in 95% of the patients...... cardiology department. Implantation of an ICD device has a central position in the treatment of patients with cardiomyopathy and ventricular tachyarrythmias and is primarily used as a prophylactic treatment. Udgivelsesdato: 2008-Jun...

  4. Fod- og ankeltraume hos patient med diabetes

    DEFF Research Database (Denmark)

    Falborg, Bettina; Ebskov, Lars

    2009-01-01

    treatment of sprains and fractures with immobilisation and a non-weight bearing period is significantly prolonged, frequently doubled, in diabetic patients. Follow-up includes frequent ambulatory controls including X-rays. If the neuroarthropathy progresses, the period of treatment is adjusted accordingly.......If confronted with a neuropathic patient with an acute foot-ankle trauma, including fracture, this patient is by definition Eichenholtz stage 0. This is of major importance for the treatment. Whereas the surgical handling of fractures does not differ from ordinary fracture treatment, the subsequent...

  5. Fod- og ankeltraume hos patient med diabetes

    DEFF Research Database (Denmark)

    Falborg, Bettina; Ebskov, Lars

    2009-01-01

    If confronted with a neuropathic patient with an acute foot-ankle trauma, including fracture, this patient is by definition Eichenholtz stage 0. This is of major importance for the treatment. Whereas the surgical handling of fractures does not differ from ordinary fracture treatment, the subsequent...... treatment of sprains and fractures with immobilisation and a non-weight bearing period is significantly prolonged, frequently doubled, in diabetic patients. Follow-up includes frequent ambulatory controls including X-rays. If the neuroarthropathy progresses, the period of treatment is adjusted accordingly...

  6. Fod- og ankeltraume hos patient med diabetes

    DEFF Research Database (Denmark)

    Falborg, Bettina; Ebskov, Lars

    2009-01-01

    If confronted with a neuropathic patient with an acute foot-ankle trauma, including fracture, this patient is by definition Eichenholtz stage 0. This is of major importance for the treatment. Whereas the surgical handling of fractures does not differ from ordinary fracture treatment, the subsequent...... treatment of sprains and fractures with immobilisation and a non-weight bearing period is significantly prolonged, frequently doubled, in diabetic patients. Follow-up includes frequent ambulatory controls including X-rays. If the neuroarthropathy progresses, the period of treatment is adjusted accordingly....

  7. Muskelstyrken hos patienter med fibromyalgi. Et litteraturstudie

    DEFF Research Database (Denmark)

    Dombernowsky, Tilde; Dreyer, Lene; Bartels, Else Marie

    2008-01-01

    Do patients with fibromyalgia (FM) have reduced muscular strength? We examined 22 articles and conclude from the results of these that FM patients have reduced muscular strength in their hands and quadriceps. The material also suggests generalised reduced muscular strength. However, the studies...... have several methodological shortcomings and future studies should be carefully designed with respect to patients as well as the control group and should be larger. To avoid CNS influence from e.g. fatigue and pain, muscular electro-stimulation may be used to ensure that the actual maximal muscular...

  8. Rehabilitering af patienter med erhvervet hjerneskade

    DEFF Research Database (Denmark)

    Rasmussen, Anne Almskou; Jørgensen, Henrik Stig; Nielsen, Jørgen Feldbæk

    2014-01-01

    the needs of patients with the most severe ABIs. Only recently rehabilitation of patients with ABI has been anchored in the medical specialty of neurology. Since then the development has taken an up-going curve. This process has been supported by The Danish Health and Medicines Authority publishing several......In Denmark the development of rehabilitation of patients with acquired brain injury (ABI) has differed from most parts of Europe. Denmark has no medical rehabilitation specialty. In 2000 two specialized hospital units were established to serve the population of 5.7 million inhabitants. They cover...... papers that highlights evidence-based organization and interventions. Current development aim to define: 1) skills of the medical doctor engaged in the rehabilitation of patients with ABI, 2) stratification to different levels of specialization at hospital and in the community, and 3) national guidelines...

  9. MBHI hos patienter med kroniske rygsmerter

    DEFF Research Database (Denmark)

    Simonsen, Erik; Kastberg, S.; Jensen, Hans Henrik

    1991-01-01

    Studied the predictive validity of the MBHI (T. Millon et al, 1982) and analyzed the differences in personality and attitudes between patients with chronic lower-back pain and patients with acute pain. Human Ss: 26 male and female adults (aged 28–60 yrs) (chronic lower-back pain); 24 male and fem...... of treatment to determine the extent of the success of the therapy. The actual success of the therapy was compared with the predictions for success based on the MBHI results. (English abstract) (PsycINFO Database Record (c) 2012 APA, all rights reserved)...

  10. Sygepleje til patienter med hepatisk encefalopati

    DEFF Research Database (Denmark)

    Ladegaard Grønkjær, Lea; Lænsø Baltzer, Rikke; Bjerg, Susanne Helle

    2014-01-01

    This article describes the nurse’s role in the treatment and care of patients with hepatic encephalopathy (HE). In order to provide a holistic care, a nurse should be aware of the triggering causes of HE and its treatment, differential diagnoses for HE and the degrees of HE severity. The article...

  11. Postoperativ morbiditet blandt alkoholmisbrugere

    DEFF Research Database (Denmark)

    Tønnesen, H; Petersen, K R; Højgaard, L

    1994-01-01

    mm2 vs 78, p Alcohol misusers had significantly longer bleeding times. Surgical stress responses, as assessed by changes in plasma cortisol and catecholamines, were higher among alcohol misusers (p ...Retrospective studies suggest increased postoperative morbidity among alcohol misusers. We have prospectively studied the risk associated with alcohol intake among patients undergoing surgery. We investigated 15 persons who required colorectal surgery and who were drinking at least five Danish...... drinks per day. These patients were matched for sex, nutrition, age, weight, cardio-pulmonary disease, diagnosis anesthesia, and surgery to 15 control persons who were consuming no more than two drinks daily. None of the patients showed signs of liver disease. The alcohol group developed more...

  12. Cancermorbiditet blandt alkoholmisbrugere

    DEFF Research Database (Denmark)

    Tønnesen, Hanne; Møller, Henrik; Andersen, Jens Richard

    1995-01-01

    , larynx, lung, pleura, and secondary cancer. The women had a significantly increased risk of cervical cancer (RR = 2.0). The men developed prostatic cancer significantly more frequently than expected (RR = 1.4). The relative risks of cancer of the stomach, pancreas, kidney and endocrine system were only......Data on the association between alcohol abuse and cancer morbidity are scarce in large cohorts of non-hospitalized alcoholic men an women. Of 18,368 alcohol abusers who entered an out-patient clinic in Copenhagen between 1954-1987, 18,307 were followed. Their cancer incidence was compared...... to that of the total Danish population. The overall morbidity of cancer was significantly increased among alcohol abusers. The men developed 1441 cancer cases (RR = 1.6), and the women 182 cases (RR = 1.5). Significantly increased incidences were found for cancer of the tongue, mouth, pharynx, oesophagus, liver...

  13. Erfaringer med akkreditering af socialt arbejde

    Directory of Open Access Journals (Sweden)

    Trine Kokholm

    2016-03-01

    med akkreditering blandt døgninstitutioner og specialskoler landet over gennem vores erfaringer med Akkreditering Danmarks kvalitetsmodel – en model som i dag anvendes af ca. 200 sociale tilbud landet over, kommunale såvel som private.

  14. Unges friluftsliv set med integrationsbriller

    DEFF Research Database (Denmark)

    Gentin, Sandra

    2010-01-01

    Det er almindelig kendt, at indvandrere ikke deltager i foreningsliv i samme omfang som etniske danskere. Det er der forsøgt rådet bod på ved at invitere unge med anden etnisk baggrund end dansk til at dyrke spejdersport i henholdsvis Varde og København NV. Tilgangen til at integrere de unge var ...... friluftsliv blandt unge etniske danskere og unge med anden etnisk baggrund....

  15. Repræsentativitet i spørgeskemaundersøgelser blandt etniske minoriteter - medborgerskabsundersøgelse

    DEFF Research Database (Denmark)

    Gorinas, Cedric; Christensen, Christiane Præstgaard

    2017-01-01

    Med udgangspunkt i medborgerskabsundersøgelsen fra 2016 har dette notat til formål at undersøge, hvad der karakteriserer de etniske grupper, som er underrepræsenterede i undersøgelsen, samt at belyse svarenes informationsgrad og foreslå metoder, som tilsigter en forbedret dataindsamling blandt et...

  16. Self-efficacy blandt apopleksipatienter

    DEFF Research Database (Denmark)

    Kristensen, Lola Qvist ,; Pallesen, Hanne

    2017-01-01

    Baggrund Flere og flere mennesker lever med følgerne af apopleksi, herunder fysiske og kognitive vanskeligheder, som begrænser mobilitet og ADL-evne. Studier har vist, at høj self-effi cacy (oplevet handlekompetence) er associeret med bedre mobilitet og ADL-evne samtidig med at det kan fremme liv...

  17. Distriktssköterskans arbete med, och erfarenhet av livsstilsförändringar hos patienter med pre-diabetes : En kvalitativ intervjustudie

    OpenAIRE

    Erlandsson, Emma; Johnson, Marit

    2016-01-01

    Syftet med denna studie var att beskriva distriktssköterskans arbete med, och erfarenhet av livsstilsförändringar hos patienter med pre-diabetes inom primärvården. Metod var en empirisk intervjustudie med en kvalitativ ansats. Åtta semistrukturerade intervjuer utfördes, intervjumaterialet analyserades utifrån Graneheim och Lundmans innehållsanalys. Resultatet visade att patienter med pre-diabetes oftast upptäcktes i samband med årskontrollen hypertoni eller då de sökte för andra besvär. Blods...

  18. Klinisk retningslinje for opsporing af angst og/eller depression hos indlagte og ambulante patienter med kronisk obstruktiv lungesygdom

    DEFF Research Database (Denmark)

    Strømstad, Grisja Vorre; Stassen, Ingelise Trosborg; Lassen Nielsen, Stine

    2015-01-01

    Formålet med den kliniske retningslinje er, at identificere screeningsredskaber der kan opspore angst og depression hos patienter med KOL, så patienter med angst og/eller depression bliver tilbudt relevant behandling....

  19. Metabolisk kontrol med insulin hos patienter med diabetes mellitus og akut myokardieinfarkt (DIGAMI 2)

    DEFF Research Database (Denmark)

    Gustafsson, Ida; Malmberg, Klas; Rydén, Lars

    2006-01-01

    Patients with diabetes have an unfavourable prognosis after an acute myocardial infarction. The DIGAMI 2 study investigated the effect of various metabolic treatment strategies in type 2 diabetic patients with acute myocardial infarction: acutely introduced, long-term insulin treatment did...

  20. Patient med myelomatose med infiltrat på røntgen af thorax

    DEFF Research Database (Denmark)

    Schoos, Ann-Marie Malby; Steentoft, Johnna; Petersen, Michael Mørk

    2010-01-01

    A 71-year-old man was referred to the lung department with pain in the right side of the chest through three months, especially when physically active. The patient presented with a tendency to shortness of breath, fatigue, low energy level and night sweats. The tentative diagnosis of pleural tumo...

  1. Reduceret cerebralt stofskifte korrelerer med MRI-forandringer og kognitiv dysfunktion hos patienter med dissemineret sklerose

    DEFF Research Database (Denmark)

    Blinkenberg, M; Rune, K; Jensen, C V

    2001-01-01

    Magnetic resonance imaging (MRI) lesion load is widely used in the clinical evaluation of patients with multiple sclerosis (MS), but little is known about the associated changes in cortical activation. For this purpose, we studied the association between the corticocerebral metabolic rate of gluc...... of glucose (CMRglc) and the MRI T2-weighted total lesion area (TLA). In addition, we investigated the correlation between cognitive and neurological disability and CMRglc....

  2. Succesfuld behandling af svær dabigatranoverdosering med idarucizumab hos en patient med nyresvigt

    DEFF Research Database (Denmark)

    Poulsen, Christina Gjerlev; Bestle, Morten; Boesby, Lene

    2017-01-01

    In the course of an uncomplicated sigmoidostomy a 63-year-old male who had severe comorbidity developed a critical bleeding due to dabigatran intoxication induced by acute kidney injury. Massive blood transfusions, tranexamic acid, Octaplex and haemodialysis were not effective. Administration of ...... of idarucizumab induced immediate clinical and paraclinical improvement. Dabigatran should be carefully administrated in patients who have any degree of renal insufficiency. Idarucizumab may be effective in severe bleeding caused by dabigatran.......In the course of an uncomplicated sigmoidostomy a 63-year-old male who had severe comorbidity developed a critical bleeding due to dabigatran intoxication induced by acute kidney injury. Massive blood transfusions, tranexamic acid, Octaplex and haemodialysis were not effective. Administration...

  3. Tværsektorielt samarbejde ved behandling af patienter med type 2-diabetes

    DEFF Research Database (Denmark)

    Munch, Lene; Røder, Michael E; Hansen, Ida H

    2018-01-01

    Hovedbudskaber • Sundhedsstyrelsen lægger vægt på tværsektorielt samarbejde omkring patienten med type 2-diabetes, men denne tankegang er dog ikke implementeret i det danske sundhedsvæsen • På organisatorisk niveau kan en stratificerings- og forløbsmodel give anvisninger til opgave- og...... udnyttelse af sundhedsvæsenets ressourcer samtidig med, at behandling af høj kvalitet fastholdes og udvikles for patienter med type 2-diabetes...

  4. Mutation of MED12 is not a frequent occurrence in prostate cancer of Korean patients

    Directory of Open Access Journals (Sweden)

    Nara Yoon

    2017-01-01

    Full Text Available Prostate cancer is one of the major health care problems, but the molecular pathogenesis has been relatively insufficiently elucidated. Recently, whole exome sequencing of prostate cancer identified recurrent mutations involving MED12 in Caucasian patients, which finding was not reproduced in one subsequent study by Sanger sequencing. Thus, we investigated mutation status of MED12 in exons 2 and 26 by Sanger sequencing in 102 radical prostatectomy cases from Korean patients. The analysis found the mutation in none of the cases. Therefore, MED12 mutation does not appear to represent a significant molecular alteration in this cohort of patients according to the analysis by the traditional "gold standard."

  5. Selvstyring af peroral antikoagulationsbehandling hos patienter med kunstige hjerteklapper

    DEFF Research Database (Denmark)

    Hasenkam, J. Michael; Kimose, H H; Grønnesby, H

    1998-01-01

    of training. No patients experienced major bleeds or thrombo-embolic events. A control group of 20 patients from our department was matched, retrospectively, to the study group. The self-managing patients were within the therapeutic INR range 78% of the study period compared to 54% for the control patients....... All self-managing patients had their median INR-value within the therapeutic range, versus only 14 in the control group. Self-management of oral anticoagulant therapy seems feasible for selected patients. Udgivelsesdato: 1998-Nov-16...

  6. Collum femoris-fraktur hos en patient med osteopetrose

    DEFF Research Database (Denmark)

    Ghasemi, Habib; Nielsen, Frank Arne Farsø; Lamm, Martin

    2015-01-01

    Osteopetrosis is a rare hereditary bone disease characterized by increased bone density. Patients with adult osteopetrosis are often diagnosed incidentally by Xray or on the presence of recurrent fractures. Internal fixations of fractures in patients with osteopetrosis are challenging due...

  7. Ustabil rygfraktur hos en patient med paranoid skizofreni

    DEFF Research Database (Denmark)

    Ydemann, Mogens

    2012-01-01

    The misdiagnosis of somatic illness in the psychiatric population can have grave consequences. Somatic symptoms are easily overseen or misinterpreted and a careful history and examination is essential when approaching this group of patients. We report a case of a patient with a history of paranoid...... schizophrenia, who had her somatic symptoms misinterpreted as being of psychiatric origin. This misinterpretation gave rise to an admission to a psychiatric ward of a patient who actually presented with an unstable spinal fracture....

  8. Bisfosfonatassocieret osteonekrose i kaeberne hos patienter med myelomatose

    DEFF Research Database (Denmark)

    Lund, Thomas; Gregersen, Henrik; Vangsted, Annette

    2009-01-01

    Bisphosphonate-associated osteonecrosis of the jaw (BON) is mainly observed in patients with multiple myeloma, and to a lesser extent in breast and prostate cancer patients receiving intravenous treatment with potent bisphosphonates. The incidence of BON increases with the duration...

  9. Behandling af kroniske sygdomme hos patienter med demens

    DEFF Research Database (Denmark)

    Pedersen, Hanne; Klinkby, Kristian Skikkild; Waldorff, Frans Borch

    2017-01-01

    Comorbidity is common in patients with dementia, and due to the nature of the dementia disease, patients with dementia have special challenges in relation to comorbidity. This article is about dementia and heart failure, chronic obstructive pulmonary disease, urinary incontinence, falls...

  10. Behandlingsresultater hos patienter med cancer i papilla Vateri

    DEFF Research Database (Denmark)

    Dahl, Sune; Bendixen, Morten; Fristrup, Claus Wilki

    2010-01-01

    Cancer of the papilla of Vater is a relatively rare disease. It is difficult to separate from other periampullary tumours at the time of diagnosis. Recent studies have shown that patients with cancer of the papilla tend survive longer than patients with pancreatic cancer and cancers of biliary...

  11. Progressiv multifokal leukoencefalopati hos en patient med myelomatose

    DEFF Research Database (Denmark)

    Willert, Cecilie Balslev; Engsig, Frederik Neess; Eskildsen, Helle Wulf

    2014-01-01

    Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disease in the central nervous system. It is caused by reactivation of John Cunningham-virus and has a grave prognosis. PML occurs most frequently in HIV-patients, but can also be seen in patients with iatrogenic immunodefic...

  12. Lavkulhydratdiæt til patienter med type 2-diabetes

    DEFF Research Database (Denmark)

    Gram-Kampmann, Eva-Marie; Olsen, Michael Hecht; Beck-Nielsen, Henning

    2016-01-01

    Recently, low-carbohydrate diets have increased in popularity as a method to achieve glycaemic control and weight loss in Type 2 diabetes patients. However, there is a lack of consistency and long-term results in existing studies on patients with Type 2 diabetes. In this review, we address current...... knowledge of low-carbohydrate diets and how they affect glycaemic control, diabetic dyslipidaemia, weight and markers of cardiovascular risk, and our aim is to aid medical practitioners in guiding patients with Type 2 diabetes who wish to try a low-carbohydrate diet in order to take control of their disease....

  13. Karakteristik, diagnostik og behandling af patienter med autoimmun hepatitis

    DEFF Research Database (Denmark)

    Ytting, Henriette; Larsen, Fin Stolze

    2012-01-01

    Autoimmune hepatitis is a relatively rare disease that may lead to rapidly progressing liver cirrhosis and even fulminant liver failure, if diagnosis and treatment is delayed or ineffective. Diagnosing the disease can be challenging, and one in five patients respond insufficiently to standard...... treatment. Patients, who are diagnosed late in the disease course or only respond partly to medical treatment, are at high risk of developing severe liver insufficiency. This article summarizes the present knowledge and evidence regarding diagnostics, therapy and disease course....

  14. Ny behandlingsstrategi for patienter med primaer, ikkeresektabel rectumcancer

    DEFF Research Database (Denmark)

    Pfeiffer, Per; Baatrup, Gunnar; Jensen, Helle Anita

    2006-01-01

    INTRODUCTION: Patients with locally advanced rectal cancer (LARC) have a poor prognosis. Preoperative radiotherapy may shrink the tumour and make subsequent resection possible. The use of modern principles of preoperative radiotherapy in combination with chemotherapy and an active surgical attitude...... increases the chance for radical surgery and cure. MATERIALS AND METHODS: A single-institution, prospective evaluation of a new treatment strategy in patients with LARC was done. RESULTS: From 1998 to 2000, 20 patients with LARC were treated with high-dose radiochemotherapy (60 Gy and chemotherapy, UFT...... of resectability should be performed at least four weeks after termination of radiotherapy. This strategy, in combination with modern surgical techniques, increases the probability of success of radical surgery and cure....

  15. Risikofaktorer for selvmord hos patienter med dissemineret sklerose

    DEFF Research Database (Denmark)

    Stenager, E N; Koch-Henriksen, N J; Stenager, E

    1997-01-01

    The purpose of the present study was to describe risk factors for suicide in patients with multiple sclerosis (MS). The study is based on available information about MS-patients identified in the Danish MS Registry with onset of disease in the period 1950-1985. In order to characterize MS suicides...... with respect to risk factors comparisons were made for male and female suicides, and for various groups of MS suicides according to disability status. The male suicides were characterized by a tendency to commit suicide in the age interval 40-49 years, the use of a violent method, previous suicidal behaviour...

  16. Telemedicinsk praehospital diagnostik og visitation af en patient med aortadissektion

    DEFF Research Database (Denmark)

    Terkelsen, Astrid Juhl; Lambrechtsen, Jess; Kaltoft, Anne

    2008-01-01

    Thoracic aortic dissection is a life-threatening emergency that must be met and surmounted immediately to increase survival. In this case, telemedicine involving ECG and GSM-based communication between the patient in the ambulance and the centre doctor was used to obtain remote pre-hospital suspi...

  17. Telemedicinsk praehospital diagnostik og visitation af en patient med aortadissektion

    DEFF Research Database (Denmark)

    Terkelsen, Astrid Juhl; Lambrechtsen, Jess; Kaltoft, Anne

    2008-01-01

    Thoracic aortic dissection is a life-threatening emergency that must be met and surmounted immediately to increase survival. In this case, telemedicine involving ECG and GSM-based communication between the patient in the ambulance and the centre doctor was used to obtain remote pre-hospital...

  18. Medicinsk behandling af patienter med primær hyperparathyroidisme

    DEFF Research Database (Denmark)

    Vestergaard, Peter; Mosekilde, Leif

    2009-01-01

    Surgery is the recommended treatment for primary hyperparathyroidism. For exceptional medical treatment, the main drugs available are cinacalcet to normalize plasma calcium, and bisphosphonates to prevent bone loss. The patients eligible for medical therapy are those who cannot be operated or whose...

  19. Udvikling af sklerodermisk krise hos patient med uerkendt sklerodermi

    DEFF Research Database (Denmark)

    Madsen, Kristine Lindhard; Hansen, Alastair; Halberg, Poul

    2014-01-01

    Less than 10% of the patients with systemic scleroderma develop renal crisis, i.e. acute renal failure and severe hypertension in most cases. Kidney biopsy shows hypertensive arteriolar changes. This complication was lethal until treatment with captopril was introduced in 1976. Since that time...

  20. Praeoperativ funktionel magnetisk resonans-billeddannelse hos patienter med hjernetumor

    DEFF Research Database (Denmark)

    Laustsen, Søren Ravn; Sørensen, Preben; Fründ, Torben

    2010-01-01

    MRI plus a three-month postoperative assessment. A total of 14 patients complied with these requirements (six men and eight women, the mean age was 39 years). fMRI raw data was collected using a three tesla magnetic resonance scanner (Signa HDx R14M5, GE Healthcare). The distance from the tumour margin...

  1. Palliativ behandling af patienter med terminal kronisk obstruktiv lungesygdom

    DEFF Research Database (Denmark)

    von Plessen, Christian; Nielsen, Thyge L; Steffensen, Ida E

    2011-01-01

    Terminal chronic obstructive pulmonary disease (COPD) and advanced cancer have similar prognosis and symptom burden. However, palliative care of patients with terminal COPD has been neglected in Denmark. We describe the symptoms of terminal COPD and suggest criteria for defining the palliative ph...

  2. Legionella pneumoni hos patienter, der er i behandling med infliximab

    DEFF Research Database (Denmark)

    Vinter, Hanne; Nielsen, Henrik Ib

    2009-01-01

    Therapy with tumour necrosis factor-alfa inhibitors is widely used in various inflammatory disorders, but adverse events from severe infections with intracellular pathogens may occur. We describe two cases of severe pulmonary legionellosis in patients treated with infliximab for Crohn's disease...

  3. High-resolution melting analysis of MED12 mutations in uterine leiomyomas in Chinese patients.

    Science.gov (United States)

    Wang, Hua; Ye, Jun; Qian, Hua; Zhou, Ruifang; Jiang, Jun; Ye, Lihua

    2015-03-01

    Somatic mutations in mediator complex subunit 12 (MED12) have emerged as a critical genetic change in the development of uterine leiomyomas. Studies, however, have focused largely on cohorts consisting of Caucasian patients. In this study, uterine leiomyomas from Chinese patients were examined for MED12 mutations. In addition, polymerase chain reaction (PCR)-based high-resolution melting analysis (HRMA) was compared with direct sequencing as a potentially more sensitive method for the detection of MED12 mutations. Tissue samples with the pathologies of uterine leiomyoma (n=181) and other endometrial diseases (n=157) were collected from Chinese patients at the Taizhou People's Hospital and Taizhou Polytechnic College (Taizhou City, China). Genomic DNA was prepared from all samples. Both PCR-based HRMA and PCR-based direct sequencing were used to detect MED12 mutations. PCR-based HRMA and direct sequencing revealed MED12 mutations in 95/181 (52.5%) and 93/181 (51.4%) uterine leiomyomas, respectively. Nearly half of these mutations (46/93) were found in a single codon, codon 131. The coincidence rate between the two methods was 98.9% (179/181) so that no statistically significant difference was evident in the application of the methodologies (χ(2)=0.011, p=0.916). In addition, MED12 mutations were identified in 1/157 (4.17%) case of other endometrial pathologies by both methods. MED12 mutations were closely associated with the development of uterine leiomyomas, as opposed to other uterine pathologies in Chinese patients, and PCR-based HRMA was found to be a reliable method for the detection of MED12 mutations.

  4. Diabetisk nefropati. Uaendret forekomst hos patienter med insulinkraevende diabetes mellitus

    DEFF Research Database (Denmark)

    Rossing, P; Rossing, K; Jacobsen, P

    1996-01-01

    Recently, a dramatic decline in the cumulative incidence of diabetic nephropathy (less than 10% after 25 years of diabetes) has been reported in IDDM patients diagnosed between 1961 and 1980. In a clinic based study we assessed recent trends in the incidence of diabetic nephropathy. All 356...... patients in whom IDDM was diagnosed before the age of 41 years between 1965 and 1979, identified in 1984 were followed to 1991 or to death. The cumulative incidence of diabetic nephropathy (urinary albumin excretion 300 mg/24 hours in two out of three consecutive samples) after 15 years of diabetes...... and in 1991 were (cumulative incidence (SE)): 18 (4)% and 35 (5)% (onset of diabetes 1965-69, n = 113), 20 (4)% and 35 (5)% (onset of diabetes 1970-74, n = 130), and 16 (5)% (onset of diabetes 1975-79, n = 113), respectively (ns). The mean (SE) haemoglobin A1c measured yearly beginning in 1984 was higher...

  5. Hurtig identifikation af patienter med neutropeni og feber bedrer prognosen

    DEFF Research Database (Denmark)

    Johansson, Sofia; Jensen, Lars Henrik

    2015-01-01

    The purpose of this article is to describe the management of febrile neutropenia in the medical emergency room. Symptoms and signs of inflammation in patients receiving chemotherapy may be blunted or absent and fever may be the only sign of severe infection. Early initiation of empirical antibiot......The purpose of this article is to describe the management of febrile neutropenia in the medical emergency room. Symptoms and signs of inflammation in patients receiving chemotherapy may be blunted or absent and fever may be the only sign of severe infection. Early initiation of empirical...... antibiotics is essential for the outcome. A beta-lactam antibiotic is the treatment of choice and the regimen should be re-evaluated frequently in absence of clinical improvement. The treating oncologist should always be involved for advice and for assuring adjustments in future chemotherapy....

  6. Praeoperativ funktionel magnetisk resonans-billeddannelse hos patienter med hjernetumor

    DEFF Research Database (Denmark)

    Laustsen, Søren Ravn; Meulengracht Sørensen, Preben; Fründ, Torben

    2010-01-01

    MRI plus a three-month postoperative assessment. A total of 14 patients complied with these requirements (six men and eight women, the mean age was 39 years). fMRI raw data was collected using a three tesla magnetic resonance scanner (Signa HDx R14M5, GE Healthcare). The distance from the tumour margin...... to fMRI activation was measured using GE-reformat version 4.2 after raw data had been postprocessed using GE BrainwavePA version 1.3.08130. The neurosurgeons valuation of fMRI in the preoperative decision-making process was obtained using a standard questionnaire. RESULTS: There was a trend...... of association between distance from tumour to eloquent functional areas and the patients' postoperative neurological outcome (Fisher's exact test: distance operate or not (42%), when deciding the surgical approach...

  7. Praeoperativ funktionel magnetisk resonans-billeddannelse hos patienter med hjernetumor

    DEFF Research Database (Denmark)

    Laustsen, Søren Ravn; Sørensen, Preben; Fründ, Torben

    2010-01-01

    MRI plus a three-month postoperative assessment. A total of 14 patients complied with these requirements (six men and eight women, the mean age was 39 years). fMRI raw data was collected using a three tesla magnetic resonance scanner (Signa HDx R14M5, GE Healthcare). The distance from the tumour margin...... to fMRI activation was measured using GE-reformat version 4.2 after raw data had been postprocessed using GE BrainwavePA version 1.3.08130. The neurosurgeons valuation of fMRI in the preoperative decision-making process was obtained using a standard questionnaire. RESULTS: There was a trend...... of association between distance from tumour to eloquent functional areas and the patients' postoperative neurological outcome (Fisher's exact test: distance operate or not (42%), when deciding the surgical approach (50...

  8. Dyb venetrombose i penis hos patient med malign sygdom

    DEFF Research Database (Denmark)

    Ghasemi, Habib; Ajan, Rullah

    2014-01-01

    Thrombosis of the deep penile venous system in a patient with a malignant disease Thrombosis of the deep penile venous system is extremely rare and must be clearly distinguished from superficial thrombosis because it may cause serious clinical complications. We present a 76-year-old man with thro...... with thrombosis of the vena dorsalis penis profunda three months after being diagnosed with disse­m­­inated non-small cell lung cancer. Total remission of the thrombosis was achieved with daily subcutaneous injections with heparin for four weeks....

  9. Clinical safety of magnetic resonance imaging in patients with implanted SynchroMed EL infusion pumps

    Energy Technology Data Exchange (ETDEWEB)

    Diehn, Felix E.; Wood, Christopher P.; Watson, Robert E.; Hunt, Christopher H. [Mayo Clinic, Department of Radiology, Rochester, MN (United States); Mauck, William D. [Mayo Clinic, Department of Anesthesiology, Rochester, MN (United States); Burke, Michelle M. [Mayo Clinic, Department of Psychiatry and Psychology, Rochester, MN (United States)

    2011-02-15

    Patients with implanted SynchroMed spinal infusion pumps (Medtronic, Inc., Minneapolis, MN) routinely undergo magnetic resonance imaging at our institution. In August 2008, Medtronic issued an urgent medical device correction report regarding several pumps. Because of the rare potential ''for a delay in the return of proper drug infusion'' and ''for a delay in the logging of motor stall events,'' ''a patient's pump must be interrogated after MRI exposure in order to confirm proper pump functionality.'' This is particularly important in patients receiving intrathecal baclofen, for whom a delay in return of proper pump infusion could lead to life-threatening baclofen withdrawal syndrome. The objective of this report is to present our experience and protocol of performing magnetic resonance imaging in patients with implanted SynchroMed EL pumps. We retrospectively reviewed records of 86 patients with implanted SynchroMed EL spinal infusion pumps who underwent 112 examinations on 1.5-T magnetic resonance imaging scanners from September 1, 1998 to July 7, 2004. No SynchroMed EL pumps were damaged by magnetic resonance imaging, and the programmable settings remained unchanged in all patients. Our data suggest that SynchroMed EL pump malfunction is indeed rare after routine clinical 1.5-T magnetic resonance imaging examinations. However, based on the Medtronic correction report, we perform pump interrogation before and after imaging. (orig.)

  10. Clinical safety of magnetic resonance imaging in patients with implanted SynchroMed EL infusion pumps

    International Nuclear Information System (INIS)

    Diehn, Felix E.; Wood, Christopher P.; Watson, Robert E.; Hunt, Christopher H.; Mauck, William D.; Burke, Michelle M.

    2011-01-01

    Patients with implanted SynchroMed spinal infusion pumps (Medtronic, Inc., Minneapolis, MN) routinely undergo magnetic resonance imaging at our institution. In August 2008, Medtronic issued an urgent medical device correction report regarding several pumps. Because of the rare potential ''for a delay in the return of proper drug infusion'' and ''for a delay in the logging of motor stall events,'' ''a patient's pump must be interrogated after MRI exposure in order to confirm proper pump functionality.'' This is particularly important in patients receiving intrathecal baclofen, for whom a delay in return of proper pump infusion could lead to life-threatening baclofen withdrawal syndrome. The objective of this report is to present our experience and protocol of performing magnetic resonance imaging in patients with implanted SynchroMed EL pumps. We retrospectively reviewed records of 86 patients with implanted SynchroMed EL spinal infusion pumps who underwent 112 examinations on 1.5-T magnetic resonance imaging scanners from September 1, 1998 to July 7, 2004. No SynchroMed EL pumps were damaged by magnetic resonance imaging, and the programmable settings remained unchanged in all patients. Our data suggest that SynchroMed EL pump malfunction is indeed rare after routine clinical 1.5-T magnetic resonance imaging examinations. However, based on the Medtronic correction report, we perform pump interrogation before and after imaging. (orig.)

  11. Praeoperativ funktionel magnetisk resonans-billeddannelse hos patienter med hjernetumor

    DEFF Research Database (Denmark)

    Laustsen, Søren Ravn; Sørensen, Preben; Fründ, Torben

    2010-01-01

    deficits by means of a standardised method for measurement of distance. A second purpose was to investigate the influence of preoperative fMRI on the neurosurgical decision-making process. MATERIAL AND METHODS: Retrospective study of 25 patients. The inclusion criteria were surgery or biopsy after f...... to fMRI activation was measured using GE-reformat version 4.2 after raw data had been postprocessed using GE BrainwavePA version 1.3.08130. The neurosurgeons valuation of fMRI in the preoperative decision-making process was obtained using a standard questionnaire. RESULTS: There was a trend......INTRODUCTION: Functional Magnetic Resonance Imaging (fMRI) allows important functions in the brain cortex to be mapped noninvasively. The purpose with this work was to investigate a possible correlation between the distance from the tumour margin to fMRI activity and postoperative neurological...

  12. Flyttemønstre, indkomster og formuer blandt ældre personer og husholdninger

    DEFF Research Database (Denmark)

    Skak, Morten; Bloze, Gintautas

    for 85-årige kvinder er steget fra knap 6 år til noget over 6 år (+½ år). Udviklingen i forskellige sundhedsindika-torer er ikke entydig, men der er en klar forbedring af almentilstan-den og et fald i andelen med diabetes og for højt blodtryk blandt de yngre pensionister. Frekvensen for ambulante...... behandlinger og ind-læggelser på sygehuse er dog samtidig stigende for alle pensionister, og det samme gælder besøg hos tandlæger, kiropraktorer, fysio- og fodterapeuter. Efter et fald frem til sidste halvdel af 1990’erne er erhvervsfrekvensen blandt de ældre igen stigende. I 2011 var knap 10 procent af de...... påvirkede af udviklingen i ejen-domsværdierne og har således udvist fald siden boligprisernes top i 2007, men ligger dog stadig over niveauet ved indgangen til nullerne. Skævheden i formuefordelingen, der er betydelig mere udtalt end for indkomsterne, er ligeledes steget. Generelt vokser de ældres formuer...

  13. Increasing Medication Possession at Discharge for Patients With Asthma: The Meds-in-Hand Project.

    Science.gov (United States)

    Hatoun, Jonathan; Bair-Merritt, Megan; Cabral, Howard; Moses, James

    2016-03-01

    Many patients recently discharged from an asthma admission do not fill discharge prescriptions. If unable to adhere to a discharge plan, patients with asthma are at risk for re-presentation to care. We sought to increase the proportion of patients discharged from an asthma admission in possession of their medications (meds in hand) from a baseline of 0% to >75%. A multidisciplinary improvement team performed 3 plan-do-study-act cycles over 2 years and, using a statistical process control chart, tracked the proportion of patients admitted with asthma discharged with meds in hand as the primary outcome. An exploratory, retrospective analysis of insurance data was conducted with a convenience sample of Medicaid-insured patients, comparing postdischarge utilization between patients discharged with meds in hand and usual care. Generalized estimating equations accounted for nonindependence in the data. Changes to the discharge process culminated in the development of a discharge medication delivery service. Outpatient pharmacist delivery of discharge medications to patient rooms achieved the project aim of 75% of patients discharged with meds in hand. In a subset of patients for whom all insurance claims were available, those discharged with meds in hand had lower odds of all-cause re-presentation to the emergency department within 30 days of discharge, compared with patients discharged with usual care (odds ratio, 0.22; 95% confidence interval, 0.05-0.99). Our initiative led to several discharge process improvements, including the creation of a medication delivery service that increased the proportion of patients discharged in possession of their medications and may have decreased unplanned visits after discharge. Copyright © 2016 by the American Academy of Pediatrics.

  14. Djur i omvårdnaden av patienter med ångest : en litteraturstudie

    OpenAIRE

    Lindgren, My; Nielsen, Anna

    2013-01-01

    Bakgrund: Antalet patienter med ångest ökar och orsakar ofta ett lidande för patienten. Sjuksköterskan har omvårdnadsansvar att lindra detta lidande. Olika djurterapier förekommer i vården för att behandla olika besvär, till exempel Animal Assisted Activity (AAA) och Animal Assisted Therapy (AAT). Syfte: Syftet med studien var att undersöka vilken påverkan djur har på patienters ångest. Metod: Studien har genomförts som en litteraturstudie baserad på kvantitativa studier(n=12). Resultat: I s...

  15. Crowdsourcing Diagnosis for Patients With Undiagnosed Illnesses: An Evaluation of CrowdMed.

    Science.gov (United States)

    Meyer, Ashley N D; Longhurst, Christopher A; Singh, Hardeep

    2016-01-14

    Despite visits to multiple physicians, many patients remain undiagnosed. A new online program, CrowdMed, aims to leverage the "wisdom of the crowd" by giving patients an opportunity to submit their cases and interact with case solvers to obtain diagnostic possibilities. To describe CrowdMed and provide an independent assessment of its impact. Patients submit their cases online to CrowdMed and case solvers sign up to help diagnose patients. Case solvers attempt to solve patients' diagnostic dilemmas and often have an interactive online discussion with patients, including an exchange of additional diagnostic details. At the end, patients receive detailed reports containing diagnostic suggestions to discuss with their physicians and fill out surveys about their outcomes. We independently analyzed data collected from cases between May 2013 and April 2015 to determine patient and case solver characteristics and case outcomes. During the study period, 397 cases were completed. These patients previously visited a median of 5 physicians, incurred a median of US $10,000 in medical expenses, spent a median of 50 hours researching their illnesses online, and had symptoms for a median of 2.6 years. During this period, 357 active case solvers participated, of which 37.9% (132/348) were male and 58.3% (208/357) worked or studied in the medical industry. About half (50.9%, 202/397) of patients were likely to recommend CrowdMed to a friend, 59.6% (233/391) reported that the process gave insights that led them closer to the correct diagnoses, 57% (52/92) reported estimated decreases in medical expenses, and 38% (29/77) reported estimated improvement in school or work productivity. Some patients with undiagnosed illnesses reported receiving helpful guidance from crowdsourcing their diagnoses during their difficult diagnostic journeys. However, further development and use of crowdsourcing methods to facilitate diagnosis requires long-term evaluation as well as validation to account

  16. Hur patienter med obotlig cancer upplever palliativ omvårdnad

    OpenAIRE

    Pereira, Cecilia; Ek, Teresia

    2011-01-01

    Bakgrund: Det beräknas att nästan var tredje person i Sverige kommer att få en cancerdiagnos i framtiden. Ungefär 40 % utav cancerfallen går inte att bota. Det finns en ökad förståelse för att den palliativa omvårdnaden är viktig för att fullända obotligt sjuka patienters välbefinnande. Syfte: Syftet med litteraturstudien var att beskriva hur patienter med obotlig cancer upplever palliativ omvårdnad. Metod: Studien har genomförts som en allmän litteraturstudie. Litteraturstudien baserades på ...

  17. Pardannelse blandt etniske minoriteter i Danmark

    DEFF Research Database (Denmark)

    Schmidt, Garbi; Jakobsen, Vibeke

    Hvor meget indflydelse har de etniske minoritetsunge i Danmark på, hvem de skal giftes med? I hvilken udstrækning forekommer der tvangsægteskaber? Og hvad er de unges - og deres forældres - holdninger til kærlighedsægteskabet? Denne undersøgelse viser, at etniske minoritetsunge ikke adskiller sig...

  18. Selvmonitorering af blodglukose og sygdomsforståelse hos patienter med insulinbehandlet diabetes. Sammenhaeng med metabolisk regulation

    DEFF Research Database (Denmark)

    Wengler, K; Matzen, L E; Sindrup, S

    1989-01-01

    values and planned reduced activity. No connection was observed between the form of treatment, level of regulation or whether the patients undertook self-monitoring and the number of hospital contacts on account of hypoglycaemia or hyperglycaemia. Metabolic regulation was not satisfactory despite self......A questionnaire investigation was undertaken to register the extent to which 212 insulin-treated diabetic patients undertook home measurements of blood glucose and the consequences which they drew from these measurements. This was compared with the metabolic regulation estimated by HbA1c....... The average HbA1c-value was 8.0%. Only 13% had HbA1c-values within the reference range for non-diabetic persons. 85% of the patients undertook self-monitoring of blood glucose. In 47.6% insulin was administered once or twice daily, 42.5% were treated with multiple injections and 9.9% employed insulin pumps...

  19. Langtidsbehandling med spinal cord-stimulation hos en patient med kronisk regionalt smertesyndrom type 1 og fantomsmerter efter amputation

    DEFF Research Database (Denmark)

    Enggaard, Thomas Peter; Scherer, Christian; Nikolajsen, Lone

    2008-01-01

    The development of stump and phantom pain after limb amputation in patients with complex regional pain syndrome (CRPS) is very frequent. Stump pain is typically recurred CRPS and the possibilities for effective pharmacological pain relief are often limited. Spinal cord stimulation (SCS) has a well...

  20. Hindringer for friluftsliv blandt ældre

    DEFF Research Database (Denmark)

    Hansen-Møller, Jette

    2010-01-01

    Frygt for personlig sikkerhed er den største hindring for et aktivt friluftsliv - tæt fulgt af mangel på nogen, at følges med og dårligt helbred - viser internationele undersøgelser. Sådanne hindringer kan forstærkes af fysiske barrierer som lang afstand eller mangel på offentlig transport til...

  1. Omgivningens betydelse för patienter med Alzheimers sjukdom : med inriktning på musik - En litteraturstudie

    OpenAIRE

    Lenander, Sara; Sancraian, Victoria

    2008-01-01

    Background: Alzheimer’s disease belongs to the largest group of dementia and stands for the half of those 37 millions persons whom are affected of dementia in the entire world. Alzheimer’s disease affects the patients with changes on their behaviour. It is important as a nurse to prevent that the symptoms increase. Music is very important for all people and it has been used in many different contexts. In order to use music in the care as an alternative to other shapes of treatments, it is ver...

  2. Patient-Provider Teamwork via Cooperative Note Taking on Tele-Board MED.

    Science.gov (United States)

    Perlich, Anja; Meinel, Christoph

    2016-01-01

    There is significant, unexploited potential to improve the patients' engagement in psychotherapy treatment through technology use. We develop Tele-Board MED (TBM), a digital tool to support documentation and patient-provider collaboration in medical encounters. Our objective is the evaluation of TBM's practical effects on patient-provider relationships and patient empowerment in the domain of talk-based mental health interventions. We tested TBM in individual therapy sessions at a psychiatric ward using action research methods. The qualitative results in form of therapist observations and patient stories show an increased acceptance of diagnoses and patient-therapist bonding. We compare the observed effects to patient-provider relationship and patient empowerment models. We can conclude that the functions of TBM - namely that notes are shared and cooperatively taken with the patient, that diagnostics and treatment procedures are depicted via visuals and in plain language, and that patients get a copy of their file - lead to increased patient engagement and an improved collaboration, communication and integration in consultations.

  3. Organisk demens blandt tandteknikere. En tvaersnitundersøgelse af tandteknikere med optikere som kontrolgruppe

    DEFF Research Database (Denmark)

    Prescott, E; Steendahl, Ulla; Damsgaard, M T

    1989-01-01

    The preparation methyl metacrylate (MMA) an organic solvent which is employed inter alii in the production of prostheses, is regarded as neurotoxic. With the object of illustrating to what extent dental technicians have symptoms compatible with organic dementia as compared with a control group, a...... after very slight exposure. Revision of the occupational environment of dental technicians, including the current hygienic limits for MMA, is recommended.......The preparation methyl metacrylate (MMA) an organic solvent which is employed inter alii in the production of prostheses, is regarded as neurotoxic. With the object of illustrating to what extent dental technicians have symptoms compatible with organic dementia as compared with a control group......, a cross-sectional questionnaire investigation was undertaken in a population consisting of 256 dental technicians and 160 opticians, all of whom were professionally active. The percentage replies for the two groups were 88 and 85 respectively. The two groups do not differ from one another as regards...

  4. Organisk demens blandt tandteknikere. En tvaersnitundersøgelse af tandteknikere med optikere som kontrolgruppe

    DEFF Research Database (Denmark)

    Prescott, E; Steendahl, Ulla; Damsgaard, M T

    1989-01-01

    The preparation methyl metacrylate (MMA) an organic solvent which is employed inter alii in the production of prostheses, is regarded as neurotoxic. With the object of illustrating to what extent dental technicians have symptoms compatible with organic dementia as compared with a control group...... of information and selection bias are discussed and it is concluded that this investigation confirms the hypothesis that symptoms compatible with organic dementia are commoner among dental technicians. The results raise the suspicion that MMA may cause acute and chronic damage to the central nervous system, even...... after very slight exposure. Revision of the occupational environment of dental technicians, including the current hygienic limits for MMA, is recommended....

  5. Organisk demens blandt tandteknikere. En tvaersnitundersøgelse af tandteknikere med optikere som kontrolgruppe

    DEFF Research Database (Denmark)

    Prescott, E; Steendahl, Ulla; Damsgaard, M T

    1989-01-01

    The preparation methyl metacrylate (MMA) an organic solvent which is employed inter alii in the production of prostheses, is regarded as neurotoxic. With the object of illustrating to what extent dental technicians have symptoms compatible with organic dementia as compared with a control group, a...... after very slight exposure. Revision of the occupational environment of dental technicians, including the current hygienic limits for MMA, is recommended....

  6. Kliniske retningslinjer for træning af aerob kapacitet og muskelstyrke til patienter med reumatoid artrit

    DEFF Research Database (Denmark)

    Larsen, Birgit Tine; Læssøe, Uffe; Kjær, Thomas

    Baggrund: Patienter med reumatoid artrit har en forhøjet risiko for udviklingen af cardio-vaskulære lidelser (CVD) ogtidlig død. Inflammation, smerter og generel træthed resulterer i nedsat muskelstyrke og lavt fysiskfunktions- og aktivitetsniveau hos mange af disse patienter, hvilket yderligere...... forstærker denne risiko. Formål: Gennem effektiv og sikker træning at øge RA patienters aerob kapacitet og muskel styrke for dermed atlette patienternes daglige aktiviteter. Patienter: Voksne patienter (> 18 år) med diagnosen reumatoid artrit ifølge ARA eller ACR/EULAR kriterierne,funktionsklasserne I, II og...... reumatoid artrit. Kortvarig landbaseret højintensitets træning af aerob kapacitet og muskelstyrke bør overvejes itræningen af patienter med reumatoid artrit. Længerevarende landbaseret højintensitets træning af aerob kapacitet og muskelstyrke bør overvejes itræningen af patienter med reumatoid artrit...

  7. Patient and staff exposure to glutaraldehyde from KeyMed Auto-Disinfector endoscope washing machine.

    Science.gov (United States)

    Lynch, D A; Parnell, P; Porter, C; Axon, A T

    1994-05-01

    Activated glutaraldehyde (2%) is the recommended agent for disinfection of endoscopic equipment. Exposure to the disinfectant is associated with side-effects and guidelines have been set to avoid these complications. Endoscope washing machines are used to provide automated high level disinfection of endoscopes as well as reduce exposure to the irritant aldehyde. We report a design fault in an endoscope washing machine which results in patients and staff being exposed to activated glutaraldehyde. The Auto-Disinfector (KeyMed) comprises a washing chamber supplied by three separate reservoirs (detergent, disinfectant, and rinse water) via a common channel. After the first cycle endoscopes are processed using previously used detergent and rinse water. Rinse water glutaraldehyde concentrations were measured in four machines during routine endoscopy lists on at least two occasions and showed a progressive rise in glutaraldehyde concentration up to 0.1% after two to six cycles. This results in staff being exposed to glutaraldehyde present on the processed instrument and the disinfectant being pumped from the internal channels of the endoscope into direct contact with the gastrointestinal mucosa during endoscopy at concentrations of 200-1000 ppm. The present atmospheric limit for glutaraldehyde is 0.2 ppm. Skin and mucosal irritation occur at concentrations of 0.3 ppm and severe synovitis in experimental animals at 100 pm. Tongue swelling and bloody diarrhoea with characteristic mucosal histological changes have been reported in patients exposed to activated glutaraldehyde on inadequately rinsed equipment. To reduce this problem the rinse water should be changed after every cycle and the endoscope should be dried thoroughly before use.

  8. Hvordan begrunder undervisere deres praksis? Et interviewstudie med undervisere fra to fagmiljøer

    Directory of Open Access Journals (Sweden)

    Anna Bager-Elsborg

    2017-03-01

    Full Text Available Formålet med denne artikel er at belyse de rationaler og begrundelser, der farver universitetsunderviseres valg af undervisningsmetoder. Med afsæt i blandt andet social praksisteori undersøges begrundelser for undervisning i interview foretaget med 17 undervisere i to forskellige fagmiljøer på et dansk universitet. Forfatteren finder, at der på trods af ligheder i metoder er meget stor forskel på de begrundelser og værdier, der ligger til grund for undervisningen, og at disse begrundelser og værdier er hentet i fagdisciplinerne.

  9. Paclitaxels farmakogenomik hos patienter med kræft i æggestokken

    DEFF Research Database (Denmark)

    Bergmann, Troels Korshøj; Mirza, Mansoor Raza; Andersen, Charlotte Brasch

    (fx ABCB1, CYP2C8, CYP3A4, SLCO1B3) korrelerer med farmakokinetik, toksicitet og effekt.  Design: Datasættet består af toksicitetsregistreringer, overlevelses-data og paclitaxelkoncentrationsbestemmelser i plasma (ende-punkter) og af SNP genotypning. Genotypen er uafhængigt og tilfældigt distribueret...

  10. Hjemtagning af dialysebehandling til grønlandske patienter med kronisk nyresvigt

    DEFF Research Database (Denmark)

    Kronborg, Christian; Kjær, Trine; Bech, Mickael

    en periode på 10 år forventes at medføre ekstraomkostninger på ca. 13,9 millioner kroner sammenlignet med at lade patienterne behandle som nu på Rigshospitalet i København. Det vil altså sige en gennemsnitlig ekstraomkostning på ca. 4 millioner kroner om året. Estimatet er dog påvirkeligt at flere...

  11. Advancing PubMed?

    DEFF Research Database (Denmark)

    Wildgaard, Lorna Elizabeth; Lund, Haakon

    2016-01-01

    Purpose Systematic reviews of biomedical literature are used to inform patient treatment. Yet the acquisition of relevant literature is proving increasingly challenging due to the large volume of information that needs to be searched, filtered and collocated. There is a need to improve...... the efficiency of biomedical literature searches. PubMed remains the primary resource for biomedical literature, and as PubMed makes the Medline data and Entrez PubMed Programming utilities freely available, any developer can produce alternative tools to search the database. The authors question if PubMed still...... 11 aspects. A systematic search in PubMed was used as study control. Findings The 16 tools limited rather than advanced the sorting, filtering, and export functionality required in a systematic search. The reproducibility of the searches in these sources was reduced. The study shows that Pub...

  12. Passion og (dis)engagement blandt unge i udskolingen

    DEFF Research Database (Denmark)

    Rasmussen, Maj Sofie

    (skateboarding, dans, basketball, musik og kunst & håndværk) som sit pædagogiske, ideologiske og organisatoriske omdrejningspunkt... Formålet med projektet er desuden at give et forskningsmæssigt bidrag til den aktuelle uddannelsespolitiske debat om reorganisering af udskolingen med henblik på at skabe øget...

  13. Produktudvikling og afsætningsøkonomisk forskning: Hvad har det med hinanden at gøre?

    DEFF Research Database (Denmark)

    Harmsen, Hanne

    2000-01-01

    Lad det være sagt med det samme. Produktudvikling er ikke et afsætningsøkonomisk kerneområde, hverken forsknings- eller undervisningsmæssigt på samme måde som eksempelvis forbrugeradfærd, reklameforskning eller industriel købsadfærd. Det skyldes blandt andet, at det er en ung forskningsretning, der...

  14. Udredning og behandling af osteoporose hos patienter med kronisk obstruktiv lungesygdom

    DEFF Research Database (Denmark)

    Eiken, Pia Agnete; Brask-Lindemann, Dorte; Vestbo, Jørgen

    2012-01-01

    Patients with chronic obstructive pulmonary disease have a high risk of osteoporosis and fractures. We present an algorithm for the prevention and treatment of osteoporosis in patients with chronic obstructive pulmonary disease....

  15. Selvmord hos patienter med apopleksi. En epidemiologisk undersøgelse

    DEFF Research Database (Denmark)

    Stenager, E N; Madsen, C; Stenager, E

    1999-01-01

    patients was increased compared to the background population, i.e. the total population of the County of Funen. The patients were followed for causes of death until end of 1989. Standard Mortality Ratios for suicide standardized for age and sex in male and female stroke patients were calculated. A total......, to improve the care of patients suffering from the impairment of a stroke. This is a continuous process, and studies are needed in order to decide how this is best done....

  16. Antibiotikumprofylakse ved tandbehandling hos patienter med hofte- eller knaeledsalloplastik er sjaeldent nødvendig

    DEFF Research Database (Denmark)

    Jørgensen, Peter Holmberg; Fuursted, Kurt; Holmstrup, Palle

    2010-01-01

    A review of the literature with respect to whether antibiotic prophylaxis should be recommended in relation to dental treatment of patients with hip or knee joint prosthesis. We find no evidence for such a general recommendation. As neutropenic patients and patients with rheumatoid arthritis...

  17. Antibiotikaresistens blandt kliniske bakterieisolater fra hunde og katte i 2013 og 2014

    DEFF Research Database (Denmark)

    Damborg, Peter Panduro

    2015-01-01

    . generationscefalosporin (indikator for extendedspektrumbeta-laktamase, ESBL) dog signifikant fra 1,7 % i 2013 til 3,8 % i 2014. Modsat faldt forekomsten af oxacillinresistente Staphylococcus pseudintermedius (indikator formethicillinresistente stammer, MRSP) fra 4,7 % i 2013 til3,0 % i 2014. Blandt begge disse vigtige...

  18. Præsentation af symptomer i almen praksis hos patienter med cancer

    DEFF Research Database (Denmark)

    Nielsen, Tine Nørgaard; Hansen, Rikke Pilegaard; Vedsted, Peter

    2010-01-01

    and prostate cancer presented diagnosis-specific symptoms (change in bowel habits, cough and bladder dysfunction) as well as more non-specific symptoms (pain, weight loss and fatigue). The GPs interpreted the symptoms as alarm symptoms in 49%, as general symptoms in 24% and as non-cancer specific symptoms...... was 3,208 corresponding to 1.7 reported symptoms per patient. The majority (57.6%) of patients presented only one symptom. Symptoms varied with the type of cancer. Patients with breast cancer and malignant melanoma mainly presented with diagnosis-specific symptoms. Patients with colorectal, lung......INTRODUCTION: For the majority of cancer patients, the diagnostic investigations begin in general practice. The aim of the study was to investigate for which symptoms cancer patients consulted their general practitioner (GP). MATERIAL AND METHODS: All newly diagnosed cancer patients and their GPs...

  19. Behandling af højt blodtryk hos patienter med akut apopleksi

    DEFF Research Database (Denmark)

    Olsen, T S; Jørgensen, H S; Garde, E

    1995-01-01

    The study was performed to investigate how often reduction of high blood pressure (> or = 220 mmHg systolic and or > or = 120 mmHg diastolic) was attempted in patients with acute stroke or transient ischemic attacks (TIA). Of 1351 consecutive patients with acute stroke or TIA 119 had high blood...... encephalopathy. It is concluded that reduction of high blood pressure in patients with stroke or TIA is attempted too often. As autoregulation is commonly impaired in acute stroke, reduction of systemic blood pressure may enhance ischaemic tissue damage. Reduction of blood pressure in acute stroke should...... pressure on admission. In 15 patients the stroke was so severe that treatment was not considered. In the remaining 104 patients reduction of the blood pressure was attempted in 28 (27%); in 23 patients immediately following admission. None of the patients had symptoms or signs of hypertensive...

  20. Antibiotikumprofylakse ved tandbehandling hos patienter med hofte- eller knaeledsalloplastik er sjaeldent nødvendig

    DEFF Research Database (Denmark)

    Jørgensen, Peter Holmberg; Fuursted, Kurt; Holmstrup, Palle

    2010-01-01

    A review of the literature with respect to whether antibiotic prophylaxis should be recommended in relation to dental treatment of patients with hip or knee joint prosthesis. We find no evidence for such a general recommendation. As neutropenic patients and patients with rheumatoid arthritis are ...... are generally more prone to develop periprosthetic infections it can be considered in these cases to give prophylactic antibiotics before more extensive dental treatments....

  1. Antibiotikumprofylakse ved tandbehandling hos patienter med hofte- eller knaeledsalloplastik er sjaeldent nødvendig

    DEFF Research Database (Denmark)

    Jørgensen, Peter Holmberg; Fuursted, Kurt; Holmstrup, Palle

    2010-01-01

    A review of the literature with respect to whether antibiotic prophylaxis should be recommended in relation to dental treatment of patients with hip or knee joint prosthesis. We find no evidence for such a general recommendation. As neutropenic patients and patients with rheumatoid arthritis...... are generally more prone to develop periprosthetic infections it can be considered in these cases to give prophylactic antibiotics before more extensive dental treatments....

  2. Effekten af cellebehandling hos patienter med kronisk iskæmisk hjertesygdom

    DEFF Research Database (Denmark)

    Mathiasen, Anders Bruun; Ali Qayyum, Abbas; Kastrup, Jens

    2015-01-01

    The present Cochrane review included 23 studies randomized placebo-controlled clinical trials with a total of 1,255 patients. The effect of autologous cell therapy versus placebo was examined on left ventricular ejection fraction (LVEF), adverse effects and mortality in patients with chronic isch...

  3. Sodium-glucose cotransporter (SGLT)-2-inhibitorer til patienter med type 2-diabetes

    DEFF Research Database (Denmark)

    Røder, Michael Einar; Storgaard, Heidi; Rungby, Jørgen

    2016-01-01

    problem. Extremely rare cases of ketoacidosis are reported, mostly in patients with Type 1 diabetes. One SGLT-2i, empagliflozin, has been shown to reduce cardiovascular mortality and progression of kidney disease in patients with Type 2 diabetes and cardiovascular disease. Outcome trials for other SGLT-2i...

  4. "Det er mit hjerte, det drejer sig om" - Eksistentielle overvejelser hos patienter med atrieflimren

    DEFF Research Database (Denmark)

    Lien Hansen, Maria; Christiansen, Anette Wendelboe; Kappel, Nanna

    2013-01-01

    Atrial fibrillation is the most common heart rhythm disturbance, and 50,000 Danes are living with this disease. Studies show reduced quality of life, including increased tendency to anxiety in the patient group. However, there are no studies dealing with anxiety in patients with atrial fibrillati...... hospitalisation. Instead they are alone with their thoughts and anxiety....

  5. Sikkerhed af magnetisk resonans-skanning hos patienter med pacemaker og implanterbar defibrillator

    DEFF Research Database (Denmark)

    Al-Sabagh, Kifah Hekmat; Christensen, Britta Ege; Thøgersen, Anna Margrethe

    2010-01-01

    INTRODUCTION: The presence of a cardiac implantable device is ICD considered an absolute contraindication to magnetic resonance imaging (MRI). The purpose of this study was to evaluate the safety of performing MRI in patients with cardiac pacemakers and ICDs that had a compelling clinical need...... for MRI examination. MATERIAL AND METHODS: During a period of nine years we have included 65 patients with cardiac devices (60 pacemakers and five ICDs) who underwent a total of 73 MRI examinations at 1.5 T. All pacemakers were reprogrammed before MRI to asynchronous mode to avoid MRI-induced inhibition...... safely in 63 patients. Inhibition of pacemaker output was observed in one patient and induction of ventricular fibrillation was observed in another with ICD. A significant increase in PCT was rare and only detected in 1% of all electrodes. CONCLUSION: MRI can be performed safely in patients...

  6. Cortical atrophy rates in Alzheimer's patients and subjects with mild cognitive impairment from the AddNeuroMed data collection

    DEFF Research Database (Denmark)

    Eskildsen, Simon Fristed; Westman, Eric; Gwadry-Sridhar, Femida

    2010-01-01

    Background: The AddNeuroMed project is a multi-centre European project which aims to identify biomarkers in Alzheimer's disease (AD). In this study we measured the rate of cortical atrophy in AD patients, subjects with mild cognitive impairment (MCI), and healthy controls (HC) using MRI. Methods...... higher atrophy rates in the left and right occipital lobes compared to HC at three months follow-up (p accelerated atrophy...... rates can be found in AD patients compared to HC and MCI. Even three months after baseline accelerated atrophy can be observed in AD compared to HC, however, the results indicate that three months is too short a period to distinguish the atrophy rates in AD and MCI. The results suggest that atrophy...

  7. Dansk Kolinesterase Kartotek udreder patienter med forlænget paralyse efter suxamethon og mivacurium

    DEFF Research Database (Denmark)

    Eskildsen, Katrine Zwicky; Gätke, Mona Ring

    2015-01-01

    The Danish Cholinesterase Research Unit (DCRU) is a nationwide unit for patients carrying mutations in the butyrylcholinesterase enzyme (BChE). BChE hydrolyzes the neuromuscular blocking drugs succinylcholine and mivacurium. Patients with mutations in the butyrylcholinesterase gene are at risk of...... of experiencing a prolonged effect of the drugs, such as weakness or paralysis for hours. In order to diagnose the referred patients correctly, DCRU combines results such as BChE activity, genotyping, pedigree and clinical reactions to succinylcholine or mivacurium....

  8. Dansk Kolinesterase Kartotek udreder patienter med forlænget paralyse efter suxamethon og mivacurium

    DEFF Research Database (Denmark)

    Eskildsen, Katrine Zwicky; Gätke, Mona Ring

    2014-01-01

    The Danish Cholinesterase Research Unit (DCRU) is a nationwide unit for patients carrying mutations in the butyrylcholinesterase enzyme (BChE). BChE hydrolyzes the neuromuscular blocking drugs succinylcholine and mivacurium. Patients with mutations in the butyrylcholinesterase gene are at risk of...... of experiencing a prolonged effect of the drugs, such as weakness or paralysis for hours. In order to diagnose the referred patients correctly, DCRU combines results such as BChE activity, genotyping, pedigree and clinical reactions to succinylcholine or mivacurium....

  9. Karotinaemi hos patient med excessivt betakarotinfødeindtag og dysreguleret diabetes mellitus

    DEFF Research Database (Denmark)

    Mikkelsen, Carsten Sauer; Mikkelsen, Dorthe Bisgaard; Lindegaard, Hanne Merete

    2009-01-01

    A case of carotinaemia in a patient with excessive beta-carotene food-intake, diabetes mellitus and physiological amenorrhea is reported. The patient developed yellow discolouration in the palms and the soles of her feet. Blood samples showed a significantly increased lever of serum beta......-carotene, but normal vitamine A value and liver enzymes. The patient reported an excessive intake of carrots (approximately 1 kg per day). The status of physiological amenorrhoea and dysregulated diabetes mellitus may have deteriorated the yellow discolouration of the skin. Udgivelsesdato: 2009-Jan-26...

  10. Effekten af Ginkgo biloba-ekstrakt hos patienter med claudicatio intermittens

    DEFF Research Database (Denmark)

    Drabaek, H; Petersen, J R; Wïnberg, N

    1996-01-01

    Eighteen patients with stable intermittent claudication were randomized in a double blind cross-over study comparing the effects of the Ginkgo biloba extract GB-8 at a dose of 120 mg o.d. with placebo. All patients were treated for three months with the active extract and three months with placebo...... and the inability to remember were both reduced, when comparing results during active treatment to placebo. Short-term memory did not change significantly. In conclusion, our study has shown that treatment with the Ginkgo biloba extract GB-8 improves some cognitive functions in elderly patients with moderate...

  11. Mannanbindende lektin og mortalitet hos patienter med type 2-diabetes--sekundaerpublikation

    DEFF Research Database (Denmark)

    Hansen, Troels Krarup; Gall, Mari-Anne; Tarnow, Lise

    2009-01-01

    We evaluated the relationship between serum mannose-binding lectin (MBL) and mortality and incident albuminuria in 326 patients with type 2 diabetes mellitus (T2DM). During 15 years of follow-up, 169 patients died. In a multivariate analysis, MBL was a significant risk factor for death from any...... cause and added to the predictive power of CRP. Normoalbuminuric patients with both high MBL and high C-reactive protein (CRP) levels had a significantly increased risk of developing albuminuria. We conclude that MBL alone or in combination with CRP can provide prognostic information on mortality...

  12. Praeoperativt delay hos patienter med perforeret ulcus: en klinisk audit fra Det Nationale Indikatorprojekt

    DEFF Research Database (Denmark)

    Møller, Morten Hylander; Nørgård, Bente Mertz; Mehnert, Frank

    2009-01-01

    size, this audit suggests that long preoperative delay in patients with peptic ulcer perforation is associated with factors related to both the internal organisation of the healthcare system, the patient's pathological picture, and the quality of diagnosis and treatment given. Udgivelsesdato: 2009-Nov......INTRODUCTION: Mortality following perforated peptic ulcer in Denmark is nearly 30%. Delayed surgery is a prognostic factor, but only half of the patients are operated within six hours of perforation - a predefined quality of care criterion in The Danish National Indicator Project. A clinical audit...... was conducted to investigate possible reasons. MATERIAL AND METHODS: All patients (n = 89) surgically treated for peptic ulcer perforation in six university hospitals in Denmark over a period of one year were included. The association between a number of predefined variables related to the internal organisation...

  13. Polyglykonat- eller polyglykolsyresutur hos patienter med forventet haemmet sårheling

    DEFF Research Database (Denmark)

    Osther, P J; Gjøde, P; Mortensen, B B

    1997-01-01

    A randomized study of abdominal fascial closure using interrupted polyglyconate and polyglycolic acid sutures after laparotomy was carried out in 204 consecutive patients with suspected impaired wound healing. There were no statistically significant differences between the two sutures with regard...... and incisional hernia after laparotomy in patients with suspected impaired wound healing but the incidence of wound infection may be reduced compared with that of multifilament polyglycolic acid suture. Udgivelsesdato: 1997-Feb-17...... to development of fascial disruption and incisional hernia. Wound infection demanding surgical intervention was found in 7% of patients with polyglyconate sutures and in 16% of those with polyglycolic acid sutures (p = 0.04). Monofilament polyglyconate suture does not reduce the incidence of fascial disruption...

  14. Praeoperativt delay hos patienter med perforeret ulcus: en klinisk audit fra Det Nationale Indikatorprojekt

    DEFF Research Database (Denmark)

    Møller, Morten Hylander; Nørgård, Bente Mertz; Mehnert, Frank

    2009-01-01

    INTRODUCTION: Mortality following perforated peptic ulcer in Denmark is nearly 30%. Delayed surgery is a prognostic factor, but only half of the patients are operated within six hours of perforation - a predefined quality of care criterion in The Danish National Indicator Project. A clinical audit...... in hospital perforation (adjusted relative risk (RR) 1.87; 95% confidence interval (CI) 0.86-4.05), 2) no classical clinical symptoms of ulcer perforation (adjusted RR with peritonism 0.32; 95% CI 0.14-0.73), 3) first physician attendance later than median time, i.e. > 25 minutes after debut (adjusted RR 2...... size, this audit suggests that long preoperative delay in patients with peptic ulcer perforation is associated with factors related to both the internal organisation of the healthcare system, the patient's pathological picture, and the quality of diagnosis and treatment given. Udgivelsesdato: 2009-Nov...

  15. Cerebralt aspergillom hos patient med immundefekt og follikulært lymfom

    DEFF Research Database (Denmark)

    Lorentzen, Kristian; Talibi, Monica Nicole; Hansen, Per Boye

    2014-01-01

    We present a case of central nervous system aspergillosis in an immunocompromised 69-year-old male with a history of chemotherapeutic treatment for follicular lymphoma. The patient presented with aphasia, apraxia and confusion. An MRI of the central nervous system and Aspergillus antigen in the s......We present a case of central nervous system aspergillosis in an immunocompromised 69-year-old male with a history of chemotherapeutic treatment for follicular lymphoma. The patient presented with aphasia, apraxia and confusion. An MRI of the central nervous system and Aspergillus antigen...

  16. Cerebralt aspergillom hos patient med immundefekt og follikulært lymfom

    DEFF Research Database (Denmark)

    Lorentzen, Kristian; Talibi, Monica Nicole; Hansen, Per Boye

    2014-01-01

    We present a case of central nervous system aspergillosis in an immunocompromised 69-year-old male with a history of chemotherapeutic treatment for follicular lymphoma. The patient presented with aphasia, apraxia and confusion. An MRI of the central nervous system and Aspergillus antigen in the s...... in the spinal fluid was suggestive for this invasive fungal infection. Despite treatment with voriconazole the patient succumbed to the infection. A rise in rare, severe infectious complications as presented is expected due to increasing dose-intensity of chemotherapy....

  17. Praeoperativt delay hos patienter med perforeret ulcus: en klinisk audit fra Det Nationale Indikatorprojekt

    DEFF Research Database (Denmark)

    Møller, Morten Hylander; Nørgård, Bente Mertz; Mehnert, Frank

    2009-01-01

    of health care, the patient's pathological picture and the quality of treatment given, and a preoperative delay of at least 6 hours was examined using modified Poisson regression analyses. RESULTS: The following variables were associated with a preoperative delay = 6 hours: 1) out of hospital versus...... was conducted to investigate possible reasons. MATERIAL AND METHODS: All patients (n = 89) surgically treated for peptic ulcer perforation in six university hospitals in Denmark over a period of one year were included. The association between a number of predefined variables related to the internal organisation...

  18. Overvægtige patienter med astma har dårligere astmakontrol

    DEFF Research Database (Denmark)

    Sivapalan, Pradeesh; Lange, Peter; Ulrik, Charlotte Suppli

    2015-01-01

    Current literature indicates that asthma is more prevalent among obese individuals. In addition, studies have shown that higher body mass index (BMI), particularly BMI ≥ 30 kg/m2, is associated with poorer asthma control and asthma-related quality of life. Furthermore, growing evidence suggests...... that obese patients with asthma respond less favourably to inhaled corticosteroids compared to non-obese patients. Moreover, longitudinal studies indicate that weight reduction improves asthma control. Therefore, preventing and treating obesity should be an integrated part of asthma management....

  19. Intensiveret multifaktoriel intervention hos patienter med type 2-diabetes mellitus og mikroalbuminuri

    DEFF Research Database (Denmark)

    Gaede, P H; Jepsen, P V; Parving, H H

    1999-01-01

    of behaviour modification, pharmacological therapy targeting hyperglycaemia, hypertension, dyslipidaemia, and microalbuminuria. The primary endpoint was development of nephropathy. Secondary endpoints were incidence or progression of diabetic retinopathy and neuropathy. Patients were followed for 3.8 years....... The intensive group had significantly lower rates of progression to hephropathy (odds ratio 0.27 [95% CI 0.10-0.75]), progression of retinopathy (0.45 (0.21-0.95]), and progression of autonomic neuropathy (0.32 [0.12-0.78]). In conclusion, intensified multifactorial intervention in patients with type 2 diabetic...

  20. Øget forekomst af depression hos patienter med hepatitis C-infektion

    DEFF Research Database (Denmark)

    Hjerrild, Simon; Renvillard, Signe Groth; Leutscher, Peter Derek Christian

    2010-01-01

    neuroinfection. Evidence to support that former intravenous drug abuse increases the risk of depression is lacking. It is particularly important to diagnose and treat depression in HCV patients as it constitutes a relative contraindication to antiviral treatment and may jeopardize therapeutic outcome.......The prevalence of depression is increased in patients with chronic hepatitis C virus (HCV) infection. Several aetiological mechanisms are thought to be involved, e.g. premorbid psychiatric disease, genetic disposition to affective disorders, socio-economic factors, stigmatization and possibly HCV...

  1. Patienter med debuterende psykose skal ikke skannes rutinemæssigt

    DEFF Research Database (Denmark)

    Ebdrup, Bjørn H; Lublin, Henrik Kai Francis; Akeson, Per

    2011-01-01

    In this systematic review of the literature, we reviewed the evidence for maintaining the current recommendation that a routine CT scan should be performed in first-episode psychotic patients (Danish National Board of Health). We identified eight papers comprising 625 CT and 214 MRI scans....... The share of potentially causal brain abnormalities was 0.8% with CT and 3.3% with MRI, but the findings had limited clinical consequences. We concluded that there is no evidence in support of performing routine CT scans of first-episode psychotic patients. If intracranial pathology is suspected clinically......, an MRI scan should be performed....

  2. Sikkerhed af magnetisk resonans-skanning hos patienter med pacemaker og implanterbar defibrillator

    DEFF Research Database (Denmark)

    Al-Sabagh, Kifah Hekmat; Christensen, Britta Ege; Thøgersen, Anna Margrethe

    2010-01-01

    INTRODUCTION: The presence of a cardiac implantable device is ICD considered an absolute contraindication to magnetic resonance imaging (MRI). The purpose of this study was to evaluate the safety of performing MRI in patients with cardiac pacemakers and ICDs that had a compelling clinical need fo...

  3. Sikkerhed af magnetisk resonans-skanning hos patienter med pacemaker og implanterbar defibrillator

    DEFF Research Database (Denmark)

    Al-Sabagh, Kifah Hekmat; Christensen, Britta Ege; Thøgersen, Anna Margrethe

    2010-01-01

    The presence of a cardiac implantable device is ICD considered an absolute contraindication to magnetic resonance imaging (MRI). The purpose of this study was to evaluate the safety of performing MRI in patients with cardiac pacemakers and ICDs that had a compelling clinical need for MRI examinat...

  4. Psykiatriloven forhindrer ikke alvorlige selvmordsforsøg hos patienter med skizofreni

    DEFF Research Database (Denmark)

    Day Poulsen, Henrik

    2012-01-01

    The Danish Mental Health Act does not prevent serious suicide attempts in patients with severe schizophrenia and a lack of compliance to medication. A case in which outpatient involuntary treatment could have prevented a very serious suicidal attempt is presented. In Denmark, outpatient involuntary...

  5. Transkateter-aortaklapimplantation hos patienter med svær aortaklapstenose

    DEFF Research Database (Denmark)

    Bjerre Thygesen, Julie; Loh, Poay Huan; Franzen, Olaf

    2012-01-01

    and relatively few serious associated complications. TAVI is now an established treatment for severe aortic stenosis in patients who have prohibitive or high surgical risk; and the treatment has proven to yield symptomatic and prognostic benefits. Innovations and advances continue in this field....

  6. Udredning og behandling af osteoporose hos patienter med prostatacancer uden knoglemetastaser

    DEFF Research Database (Denmark)

    Eiken, Pia A; Langdahl, Bente Lomholt; Eiken, Frederik L

    2011-01-01

    The prevention of cancer treatment-induced bone loss in patients with prostate cancer due to gonadotropin-releasing hormone (GnRH)-agonist, GnRH-antagonist and orchidectomi therapy has a high priority. We present an algorithm for the prevention and treatment of osteoporosis during treatment of non...

  7. Forebyggelse af skeletrelaterede hændelser hos patienter med knoglemetastaser ved solide tumorer

    DEFF Research Database (Denmark)

    Kamby, Claus; Tarp, Simon; Mellemgaard, Anders

    2014-01-01

    This article is based on a systematic literature search and meta-analyses of clinical data regarding effects of bisphosphonates (BP) and denosumab (DS) on preventing skeletal related events (SRE) in patients with bone metastases from solid tumours. Although there are pharmacological differences b...

  8. Ny glukosestyret pumpe til stram glukosekontrol hos patient med diabetes under graviditet

    DEFF Research Database (Denmark)

    Pilemann-Lyberg, Sascha; Solis, Anette Bratt; Mathiesen, Elisabeth R

    2014-01-01

    Continuous glucose monitoring enables innovative insulin pumps to stop infusion of insulin at selected blood glucose thresholds. We present the first and successful Danish clinical case using this device, a Medtronics Veo insulin pump, in a patient with numerous cases of severe hypoglycaemia during...... earlier pregnancies. During this treatment insulin infusion was frequently stopped and severe hypoglycaemia prevented in the remaining part of pregnancy....

  9. Cowdens syndrom diagnosticeret hos patienter med store hoveder, falske vorter og struma

    DEFF Research Database (Denmark)

    Skytte, Anne-Bine; Bojesen, Anders; Bygum, Anette

    2014-01-01

    Cowden syndrome is a rare autosomal dominant syndrome with a predisposition to cancer. We present a case of Cowden syndrome in a mother and her son, who were diagnosed with palmoplantar hyperkeratosis, macrocephaly and goitre. Early diagnosis is a challenge as the patients present with a variety...

  10. Udredning og behandling af osteoporose hos patienter med prostatacancer uden knoglemetastaser

    DEFF Research Database (Denmark)

    Eiken, Pia Agnete; Langdahl, Bente Lomholt; Eiken, Frederik L

    2011-01-01

    The prevention of cancer treatment-induced bone loss in patients with prostate cancer due to gonadotropin-releasing hormone (GnRH)-agonist, GnRH-antagonist and orchidectomi therapy has a high priority. We present an algorithm for the prevention and treatment of osteoporosis during treatment of no...

  11. Medicinsk behandling af osteoporose hos patienter med moderat til svaert nedsat nyrefunktion

    DEFF Research Database (Denmark)

    Eiken, Pia A; Vestergaard, Peter

    2012-01-01

    Both chronic kidney disease and osteoporosis are frequent conditions in the general population. Most drugs for treating osteoporosis seem safe in terms of affecting renal function for patients with mildly to moderate decreased renal function. There are very few data on the efficacy (reduction in ...

  12. Rehabilitering og palliation af patienter med svær KOL bør integreres

    DEFF Research Database (Denmark)

    Ringbæk, Thomas; Wilcke, Jon Torgny Rostrup

    2013-01-01

    Treatment elements of rehabilitation and palliative care are described in relation to the main clinical manifestations of severe and very severe chronic obstructive pulmonary disease (COPD). With increasing loss of function the need for multidisciplinary effort increases. Physiotherapy...... especially for patients with frequent exacerbations....

  13. Hjertepakken forkorter udredningsforløbet for patienter med iskæmisk hjertesygdom

    DEFF Research Database (Denmark)

    Andersen, Nikolaj Stevnbak; Jensen, Jesper Møller; Sejr-Knudsen, Anne

    2011-01-01

    to have no need for further testing at the first examination, 32% were referred to coronary angiography, 33% to coronary CT angiography, 7% to myocardial perfusion imaging and 8% to exercise testing. 88% of patients achieved a diagnosis within 21 days from the first clinical examination....

  14. Ny glukosestyret pumpe til stram glukosekontrol hos patient med diabetes under graviditet

    DEFF Research Database (Denmark)

    Pilemann-Lyberg, Sascha; Solis, Anette Bratt; Mathiesen, Elisabeth R

    2014-01-01

    Continuous glucose monitoring enables innovative insulin pumps to stop infusion of insulin at selected blood glucose thresholds. We present the first and successful Danish clinical case using this device, a Medtronics Veo insulin pump, in a patient with numerous cases of severe hypoglycaemia duri...

  15. Telemedicinsk praehospital diagnostik og visitation af en patient med akut lungeemboli

    DEFF Research Database (Denmark)

    Terkelsen, Astrid J.; Nielsen-Kudsk, Jens Erik; Andersen, Henning Rud

    2008-01-01

    Mortality in untreated pulmonary embolism is high and short-term outcome depends on a timely diagnosis. In this case telemedicine involving 12-lead ECG and GSM-based communication between the patient in the ambulance and the telemedical staff resulted in remote pre-hospital suspicion of acute...

  16. Praeoperativt delay hos patienter med perforeret ulcus: en klinisk audit fra Det Nationale Indikatorprojekt

    DEFF Research Database (Denmark)

    Møller, Morten Hylander; Nørgård, Bente Mertz; Mehnert, Frank

    2009-01-01

    Mortality following perforated peptic ulcer in Denmark is nearly 30%. Delayed surgery is a prognostic factor, but only half of the patients are operated within six hours of perforation - a predefined quality of care criterion in The Danish National Indicator Project. A clinical audit was conducted...

  17. 50-års-registerefterundersøgelse af 112 patienter med klassisk neurosediagnose

    DEFF Research Database (Denmark)

    Jepsen, Peter Winning; Juel, Knud; Bech, Per

    2007-01-01

    INTRODUCTION: The study is a register follow-up on a group of patients with a diagnosis of neurosis according to the Danish psychiatric/psychoanalytical tradition. The study group consists of the 'hospital material' used by the late Erling Jacobsen, M.D., in his doctoral thesis of 1965. MATERIALS...

  18. Padma-28, et urtepraeparat, øger gangdistancen hos patienter med claudicatio intermittens

    DEFF Research Database (Denmark)

    Drabaek, H; Mehlsen, J; Petersen, J R

    1994-01-01

    Thirty-six patients with stable intermittent claudication were randomized in a doubleblind study either to treatment with two tablets of Padma-28 twice daily (containing 340 mg dried herbal mixture composed according to an ancient lamaistic prescription) or placebo for four months. Effect...

  19. Immunmodulerende effekt af LongoVital hos patienter med recidiverende aftøs stomatit. 2

    DEFF Research Database (Denmark)

    Pedersen, A; Klausen, B; Hougen, H P

    1991-01-01

    LongoVital (LV) (DK. reg. no. 5178/75) is a herbal-based tablet enriched with recommended doses of vitamins. Peripheral lymphocyte subsets: T-helper/CD4 (OKT4+) and T-suppressor/cytotoxic/CD8 (OKT8+) were studied quantitatively in 31 otherwise healthy patients with minor recurrent aphthous...

  20. Zygomycosis (mucormycosis) hos patienter med malign hæmatologisk lidelse

    DEFF Research Database (Denmark)

    Jensen, Eva Magrethe Precht; Clemmensen, Stine; Bjørndal, Kristine

    2011-01-01

    Zygomycosis is an invasive and increasingly emerging life-threatening infection. Diabetes is the most common risk factor; however, zygomycosis has increased among patients with haematologic malignancy, which is now the second most common risk factor with an incidence of 16%. Rapid diagnosis and t...

  1. Faktorer af betydning for tidlig og sen indlaeggelse af patienter med apopleksi og transitorisk cerebral iskaemi

    DEFF Research Database (Denmark)

    Rasmussen, Berit H; Germer, Ulla; Kammersgaard, Lars Peter

    2003-01-01

    predictors of early admission. DISCUSSION: Patients with stroke or TIA in a Danish metropolitan area arrive at hospital a median of 2.6 hours after the stroke. Admission by ambulance after calling emergency was associated with the shortest onset to admission time. Udgivelsesdato: 2003-Jan-13...

  2. Effekten af Ginkgo biloba-ekstrakt hos patienter med claudicatio intermittens

    DEFF Research Database (Denmark)

    Drabaek, H; Petersen, J R; Wïnberg, N

    1996-01-01

    and the inability to remember were both reduced, when comparing results during active treatment to placebo. Short-term memory did not change significantly. In conclusion, our study has shown that treatment with the Ginkgo biloba extract GB-8 improves some cognitive functions in elderly patients with moderate...

  3. Answers to questions posed during daily patient care are more likely to be answered by UpToDate than PubMed.

    Science.gov (United States)

    Hoogendam, Arjen; Stalenhoef, Anton F H; Robbé, Pieter F de Vries; Overbeke, A John P M

    2008-10-03

    UpToDate and PubMed are popular sources for medical information. Data regarding the efficiency of PubMed and UpToDate in daily medical care are lacking. The purpose of this observational study was to describe the percentage of answers retrieved by these information sources, comparing search results with regard to different medical topics and the time spent searching for an answer. A total of 40 residents and 30 internists in internal medicine working in an academic medical center searched PubMed and UpToDate using an observation portal during daily medical care. The information source used for searching and the time needed to find an answer to the question were recorded by the portal. Information was provided by searchers regarding the topic of the question, the situation that triggered the question, and whether an answer was found. We analyzed 1305 patient-related questions sent to PubMed and/or UpToDate between October 1, 2005 and March 31, 2007 using our portal. A complete answer was found in 594/1125 (53%) questions sent to PubMed or UpToDate. A partial or full answer was obtained in 729/883 (83%) UpToDate searches and 152/242 (63%) PubMed searches (P UpToDate answered more questions than PubMed on all major medical topics, but a significant difference was detected only when the question was related to etiology (P UpToDate and 291 seconds (SD 7) for PubMed. Specialists and residents in internal medicine generally use less than 5 minutes to answer patient-related questions in daily care. More questions are answered using UpToDate than PubMed on all major medical topics.

  4. Effekten af Ginkgo biloba-ekstrakt hos patienter med claudicatio intermittens

    DEFF Research Database (Denmark)

    Drabaek, H; Petersen, J R; Wïnberg, N

    1996-01-01

    Eighteen patients with stable intermittent claudication were randomized in a double blind cross-over study comparing the effects of the Ginkgo biloba extract GB-8 at a dose of 120 mg o.d. with placebo. All patients were treated for three months with the active extract and three months with placebo....... The effects of treatment on arterial insufficiency were quantified by measurements of systemic and peripheral systolic blood pressures, and pain-free and maximal walking distances on a tread-mill. Questionnaires based on visual analogue scales were used to quantify the severity of leg pain, impairment...... of concentration, and inability to remember. Short-term memory was objectively assessed. We did not find any significant changes in either peripheral blood pressures, walking distances or the severity of leg pain. Systemic blood pressure was reduced both by placebo and GB-8. The impairment of concentration...

  5. Herpes simplex-virus type 1 påvist hos patient med herpes zoster

    DEFF Research Database (Denmark)

    Danielsen, Patricia Louise; Schønning, Kristian; Larsen, Helle Kiellberg

    2012-01-01

    In this case report we present an otherwise healthy 63 year-old male patient with herpes zoster corresponding to the 2nd left branch of the trigeminal nerve. Real time-polymerase chain reaction analyses were positive for both herpes simplex virus (HSV) type 1 and varicella zoster virus (VZV......). The most probable explanation is that this reflects asymptomatic, latent expression of HSV-1 in a herpes zoster patient with no clinical relevance. Another hypothesis is that reactivation of a neurotropic herpes virus can reactivate another neurotropic virus if both types are present in the same ganglion....... If co-infection with HSV/VZV is suspected the treatment regimen for herpes zoster will sufficiently treat a possible HSV infection also....

  6. Praeoperativt delay hos patienter med perforeret ulcus: en klinisk audit fra Det Nationale Indikatorprojekt

    DEFF Research Database (Denmark)

    Møller, Morten Hylander; Nørgård, Bente Mertz; Mehnert, Frank

    2009-01-01

    INTRODUCTION: Mortality following perforated peptic ulcer in Denmark is nearly 30%. Delayed surgery is a prognostic factor, but only half of the patients are operated within six hours of perforation - a predefined quality of care criterion in The Danish National Indicator Project. A clinical audit...... of health care, the patient's pathological picture and the quality of treatment given, and a preoperative delay of at least 6 hours was examined using modified Poisson regression analyses. RESULTS: The following variables were associated with a preoperative delay = 6 hours: 1) out of hospital versus...... in hospital perforation (adjusted relative risk (RR) 1.87; 95% confidence interval (CI) 0.86-4.05), 2) no classical clinical symptoms of ulcer perforation (adjusted RR with peritonism 0.32; 95% CI 0.14-0.73), 3) first physician attendance later than median time, i.e. > 25 minutes after debut (adjusted RR 2...

  7. Praeoperativt delay hos patienter med perforeret ulcus: en klinisk audit fra Det Nationale Indikatorprojekt

    DEFF Research Database (Denmark)

    Møller, Morten Hylander; Nørgård, Bente Mertz; Mehnert, Frank

    2009-01-01

    was conducted to investigate possible reasons. MATERIAL AND METHODS: All patients (n = 89) surgically treated for peptic ulcer perforation in six university hospitals in Denmark over a period of one year were included. The association between a number of predefined variables related to the internal organisation...... of health care, the patient's pathological picture and the quality of treatment given, and a preoperative delay of at least 6 hours was examined using modified Poisson regression analyses. RESULTS: The following variables were associated with a preoperative delay = 6 hours: 1) out of hospital versus...... in hospital perforation (adjusted relative risk (RR) 1.87; 95% confidence interval (CI) 0.86-4.05), 2) no classical clinical symptoms of ulcer perforation (adjusted RR with peritonism 0.32; 95% CI 0.14-0.73), 3) first physician attendance later than median time, i.e. > 25 minutes after debut (adjusted RR 2...

  8. Præoperativ funktionel magnetisk resonans-billeddannelse hos patienter med hjernetumor

    DEFF Research Database (Denmark)

    Laustsen, Søren Ravn; Sørensen, Preben; Fründ, Torben

    2010-01-01

    MRI plus a three-month postoperative assessment. A total of 14 patients complied with these requirements (six men and eight women, the mean age was 39 years). fMRI raw data was collected using a three tesla magnetic resonance scanner (Signa HDx R14M5, GE Healthcare). The distance from the tumour margin...... to fMRI activation was measured using GE-reformat version 4.2 after raw data had been postprocessed using GE BrainwavePA version 1.3.08130. The neurosurgeons valuation of fMRI in the preoperative decision-making process was obtained using a standard questionnaire. RESULTS: There was a trend...... of association between distance from tumour to eloquent functional areas and the patients' postoperative neurological outcome (Fisher's exact test: distance operate or not (42%), when deciding the surgical approach...

  9. Organisation af behandling og opfølgning af patienter med type 2-diabetes

    DEFF Research Database (Denmark)

    Drivsholm, Thomas Bo; Snorgaard, Ole

    2012-01-01

    The organization of treatment and control of type 2 diabetic patients in Denmark has undergone a major development within the last decade. From being based on local hospital guidelines, treatment and control have moved towards a more organized collaboration between primary and secondary care based...... on common national guidelines. Quality indicators from primary and secondary care are collected routinely, and gradually an increasingly precise depiction is documented in the National Indicator Project....

  10. Anæstesi til patienter med kroniske sår

    DEFF Research Database (Denmark)

    Hjort, Mathias; Hyllested, Mette; Jørgensen, Bo

    2015-01-01

    Perioperative management of chronic wounds demands a multidisciplinary approach. Severe co-morbidities leave these patients prone to post-operative complications. To optimize wound healing, minimally invasive methods, both surgical and anaesthesiological, are applied. Ultrasound-guided peripheral...... nerveblocks (PNB) are an ideal anaesthesia method for wound revisions, amputations and split skin transplantations. The implementation of PNB allows continued anticoagulant treatment, provides post-operative analgesia, lowers opioid consumption and facilitates mobilization....

  11. Effekten af Ginkgo biloba-ekstrakt hos patienter med claudicatio intermittens

    DEFF Research Database (Denmark)

    Drabaek, H; Petersen, J R; Wïnberg, N

    1996-01-01

    of concentration, and inability to remember. Short-term memory was objectively assessed. We did not find any significant changes in either peripheral blood pressures, walking distances or the severity of leg pain. Systemic blood pressure was reduced both by placebo and GB-8. The impairment of concentration...... and the inability to remember were both reduced, when comparing results during active treatment to placebo. Short-term memory did not change significantly. In conclusion, our study has shown that treatment with the Ginkgo biloba extract GB-8 improves some cognitive functions in elderly patients with moderate...

  12. Molekylaere mekanismer bag den immunologiske reaktion mod gluten hos patienter med cøliaki

    DEFF Research Database (Denmark)

    Nielsen, Christian; Husby, Steffen; Lillevang, Søren T

    2003-01-01

    Coeliac disease is a complex inflammatory disorder of the small intestine, induced by dietary gluten in genetically susceptible individuals. Recently, the nature of gluten-derived peptides recognized by gut-derived T cells from patients has been elucidated. It has further been established...... that the binding of such peptides to HLA-DQ2 and DQ8 molecules is enhanced following the modification of the peptides by the ubiquitous enzyme tissue transglutaminase. This knowledge has allowed the establishment of a molecular basis for the well-known association between coeliac disease and the expression...... of these HLA-molecules. This article summarizes the latest progress in coeliac disease molecular biology....

  13. Transkateter-aortaklapimplantation hos patienter med svær aortaklapstenose

    DEFF Research Database (Denmark)

    Bjerre Thygesen, Julie; Loh, Poay Huan; Franzen, Olaf

    2012-01-01

    In the late 1980's, Denmark was the birthplace for the concept of transcatheter valve implantation. In 2002, the first successful transcatheter aortic valve implantation (TAVI) was performed in humans. TAVI has matured beyond the learning-curve period with a high overall procedural success rate...... and relatively few serious associated complications. TAVI is now an established treatment for severe aortic stenosis in patients who have prohibitive or high surgical risk; and the treatment has proven to yield symptomatic and prognostic benefits. Innovations and advances continue in this field....

  14. Antithyroideaantistof hos to patienter med subakut dementiel udvikling, ataksi og myoklonus

    DEFF Research Database (Denmark)

    Kondziella, Daniel; Hansen, Klaus; Gonzalez, Teresa

    2012-01-01

    Hashimoto encephalitis (HE) is a steroid-responsive autoimmune encephalitis with anti-thyroid antibodies; Creutzfeldt-Jakob disease (CJD) is a prion disease. Both disorders can have a similar clinical presentation. Two women, 67 and 63 year-old, with subacute dementia, ataxia, myoclonus...... and positive antithyroid antibodies were given oral steroids. Whereas one progressively declined and had histopathologically proven CJD, the other made a complete recovery and was diagnosed with HE. Anti-thyroid antibodies can occur in CJD, but when present in a patient with subacute dementia, ataxia...

  15. Sikkerhed af magnetisk resonans-skanning hos patienter med pacemaker og implanterbar defibrillator

    DEFF Research Database (Denmark)

    Al-Sabagh, Kifah Hekmat; Christensen, Britta Ege; Thøgersen, Anna Margrethe

    2010-01-01

    INTRODUCTION: The presence of a cardiac implantable device is ICD considered an absolute contraindication to magnetic resonance imaging (MRI). The purpose of this study was to evaluate the safety of performing MRI in patients with cardiac pacemakers and ICDs that had a compelling clinical need...... or to sense only mode to avoid MRI-induced competitive pacing and potential pro-arrhythmia. All devices were interrogated immediately before and after the MRI examination, which included measurement of sensitivity, pacing capture threshold (PCT) and lead impedance. RESULTS: MRI examinations were completed...

  16. Burned-out seminom-lymfeknudemetastasepå halsen hos en patient med radikalt behandlet cancer coli

    DEFF Research Database (Denmark)

    Juul, Marie Louise; Rasmussen, Eva Rye

    2017-01-01

    and at the neck. A core needle biopsy from the lymph node at the neck contained malignant cells, but not from colon cancer. The lymph node was extirpated, and pathological analysis proved it to be a metastasis from a testicular seminoma. A burned-out seminoma was subsequently found in the patient's right testicle.......The incidence of metastases to the neck in testicular cancer is 4-15%, and in 5% of these cases the metastasis is the only symptom. We present a 57-year-old asymptomatic male, who had previously been treated for colon cancer. A routine PET-CT showed enlarged lymph nodes in the retroperitoneum...

  17. Talaromyces marneffei-fungæmi i patient fra Thailand med nydiagnosticeret hiv

    DEFF Research Database (Denmark)

    Nørredam, Marie; Porskrog, Anders; Ocias, Lukas Frans

    2017-01-01

    Talaromyces marneffei is a dimorphic fungus, which may cause life-threatening opportunistic infections in immuno-compromised individuals. A 25-year-old woman from Thailand was admitted with fever, shortness of breath, cough, and weight loss. The symptoms had persisted for three weeks. The patient...... had a stopover in Copenhagen on her way to Thailand from Greenland. A thoracic X-ray showed bilateral interstitial changes. Examinations showed positive HIV-test with a CD4-count of 21/microlitre. Moreover, fungaemia with T. marneffei was detected by cultivation. Highly active antiretroviral therapy...

  18. Et Patientperspektivistisk Studie i Brug af Alternativ Behandling hos Danske Patienter med Diabetes

    DEFF Research Database (Denmark)

    Gerbild, Helle Nygaard

    2008-01-01

    prevalence in use of CAM, which is generally rather low, especially the CAM used specifically for diabetes. The objective of this paper is to develop concepts to understand patients having experiences and positions of diabetes in their use of CAM. Methods: This qualitative study its inspiration from grounded...... treatment, and this to a relatively low degree. Analyses show that they do not have the strength to follow the conventional recommendations and the alternative self-care management (CAM) at the same time, which may contribute to the understanding of diabetic non-CAM positions. Some of the established...... clients, however, are positioned as user of both complementary and alternative medicine and conventional treatments, such as biological, homeopathic, and traditional Chinese medicine. The main factors that drive them to this are the aim, the hope, the belief, and knowledge how to cure diabetes. Conclusion...

  19. Antithyroideaantistof hos to patienter med subakut dementiel udvikling, ataksi og myoklonus

    DEFF Research Database (Denmark)

    Kondziella, Daniel; Hansen, Klaus; Gonzalez, Teresa

    2012-01-01

    Hashimoto encephalitis (HE) is a steroid-responsive autoimmune encephalitis with anti-thyroid antibodies; Creutzfeldt-Jakob disease (CJD) is a prion disease. Both disorders can have a similar clinical presentation. Two women, 67 and 63 year-old, with subacute dementia, ataxia, myoclonus and posit......Hashimoto encephalitis (HE) is a steroid-responsive autoimmune encephalitis with anti-thyroid antibodies; Creutzfeldt-Jakob disease (CJD) is a prion disease. Both disorders can have a similar clinical presentation. Two women, 67 and 63 year-old, with subacute dementia, ataxia, myoclonus...... and positive antithyroid antibodies were given oral steroids. Whereas one progressively declined and had histopathologically proven CJD, the other made a complete recovery and was diagnosed with HE. Anti-thyroid antibodies can occur in CJD, but when present in a patient with subacute dementia, ataxia...

  20. Risikofaktorer for selvmordsforsøg blandt børn og unge

    DEFF Research Database (Denmark)

    Christoffersen, Mogens

    Danske undersøgelser viser, at der er en markant overhyppighed af selvmordsforsøg og selvmordsovervejelser blandt unge, der har været udsat for vold, incest og seksuelle overgreb fra de nærmeste. Et tydeligt kendetegn har også været, at de unge har ønsket at flytte hjemmefra tidligt, at de har haft...

  1. Pengespil blandt unge i Danmark 2007-2016

    DEFF Research Database (Denmark)

    Fridberg, Torben; Birkelund, Jesper Fels

    2016-01-01

    unge, der i 2007 havde en risikabel spilleadfærd. Undersøgelsen viser, at selv om udbuddet af pengespil er blevet større, så spiller færre unge om penge i 2016 end i 2007. Den viser desuden, at der ikke er flere unge, der er i risiko for at få problemer med pengespil. Undersøgelsen er finansieret af...

  2. Interview med professor Paul du Gay om bureaukratiets værdi

    DEFF Research Database (Denmark)

    Pors, Anja Svejgaard

    2013-01-01

    Paul du Gay er sociolog og globaliseringsprofessor ved Institut for Organisation på Copenhagen Business School. I hans forskning interesserer han sig blandt andet for bureaukratiet som styreform. Gennem årtier har bureaukratiet været genstand for omfattende kritik for dets langsommelighed......, inhumanitet og manglende fleksibilitet. Paul du Gay har taget til genmæle og forsvarer bureaukratiet som en styreform, der understøtter demokrati. I arbejdet med administration som praksis og faglighed har vi interviewet Paul du Gay om nogle af de centrale pointer i denne forskning. Samtalen kredser om...

  3. Blogs - Læringsfællesskab med rum til refleksion

    DEFF Research Database (Denmark)

    Danbjørg, Dorthe Boe; Clemensen, Jane; Hansen, Pernille Stenkil

    2018-01-01

    Anvendelse af blogs i læringssituationer kan give studerende mulighed for at reflektere i fællesskab. Derfor blev blogs afprøvet blandt universitetsstuderende med det formål at undersøge, hvordan studerende oplever anvendelsen af blogmediet, samt undersøge hvilke former for refleksion, som blogs...... kan understøtte. Undersøgelsen var baseret på en sociokulturel forståelse af læring, hvor læring ses som en proces, der konstrueres gennem interaktioner. Blogs blev afprøvet som en del af et undervisningsforløb for 24 studerende. Blogindlæggene blev analyseret mhp at identificere refleksionsniveauet...... uklarhed over opgaven og usikkerhed på hvordan blogmediet anvendes. Endelig kan anvendelsen af blogs i læringssituationer udfordre de gængse opfattelser af læring, hvilket kan skabe forvirring hos de studerende....

  4. Peer til peer i arbejdet med udsatte mennesker

    DEFF Research Database (Denmark)

    Ahlmark, Nanna; Norrhäll, Oskar; Jensen, Pernille Hartvig

    Statens Institut for Folkesundhed, Syddansk Universitet har fået til opdrag at lave en formativ procesevaluering af Københavns Kommunes projekt Mænd i København. Projektet omhandler udvikling og implementering af en peer til peer indsats med henblik på at forbedre sundhed og trivsel blandt udsatte...... mænd i risiko for at udvikle type 2 diabetes. En del af evalueringsopdraget har været at tilvejebringe viden om relevant litteratur om peer-metoder. I denne forbindelse er dette notat udarbejdet til Københavns Kommunes Forebyggelsescenter Nørrebro af evaluerings-teamet, som består af forsker, Nanna...... Ahlmark, adjunkt ved Aalborg Universitet Camilla Dindler, praktikant og specialestuderende Oskar Norrhäll og specialestuderende Pernille Hartvig Jensen. Notatet er en sammenfatning af udvalgt forskningslitteratur og rapporter om peer til peer-relaterede projekter målrettet udsatte grupper i forbindelse...

  5. "Sikker sex" blandt hiv-smittede heteroseksuelle par

    DEFF Research Database (Denmark)

    Weis, N M; Skinnes, L; Vesterdal, B

    1999-01-01

    To investigate the use of condoms ("safe sex") as prevention of transmission with human immuno deficiency virus (hiv) among heterosexual couples, 57 hiv-positive heterosexual patients and their partners if there was one interviewed. Forty-three of the 57 patients were heterosexually infected. Five...... out of 30 patients involved in a relationship (defined as living together for at least three months) used condoms inconsistently. One of these couples was still discordant. Of the remaining 27 patients without steady partners two used condoms inconsistently. The patients expressed great satisfaction...... at being given the possibility of talking about problems regarding hiv-transmission and sexuality. In conclusion a discrepancy was found between knowledge about transmission of hiv and the use of condoms among heterosexual couples. Udgivelsesdato: 1999-Jun-14...

  6. "Sikker sex" blandt hiv-smittede heteroseksuelle par

    DEFF Research Database (Denmark)

    Weis, N M; Skinnes, L; Vesterdal, B

    1999-01-01

    To investigate the use of condoms ("safe sex") as prevention of transmission with human immuno deficiency virus (hiv) among heterosexual couples, 57 hiv-positive heterosexual patients and their partners if there was one interviewed. Forty-three of the 57 patients were heterosexually infected. Fiv...... at being given the possibility of talking about problems regarding hiv-transmission and sexuality. In conclusion a discrepancy was found between knowledge about transmission of hiv and the use of condoms among heterosexual couples. Udgivelsesdato: 1999-Jun-14......To investigate the use of condoms ("safe sex") as prevention of transmission with human immuno deficiency virus (hiv) among heterosexual couples, 57 hiv-positive heterosexual patients and their partners if there was one interviewed. Forty-three of the 57 patients were heterosexually infected. Five...... out of 30 patients involved in a relationship (defined as living together for at least three months) used condoms inconsistently. One of these couples was still discordant. Of the remaining 27 patients without steady partners two used condoms inconsistently. The patients expressed great satisfaction...

  7. MedSun Reports

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Medical Product Safety Network (MedSun) is an adverse event reporting program launched in 2002. The primary goal for MedSun is to work collaboratively with the...

  8. "Sikker sex" blandt hiv-smittede heteroseksuelle par

    DEFF Research Database (Denmark)

    Weis, N M; Skinnes, L; Vesterdal, B

    1999-01-01

    To investigate the use of condoms ("safe sex") as prevention of transmission with human immuno deficiency virus (hiv) among heterosexual couples, 57 hiv-positive heterosexual patients and their partners if there was one interviewed. Forty-three of the 57 patients were heterosexually infected. Fiv...... at being given the possibility of talking about problems regarding hiv-transmission and sexuality. In conclusion a discrepancy was found between knowledge about transmission of hiv and the use of condoms among heterosexual couples. Udgivelsesdato: 1999-Jun-14......To investigate the use of condoms ("safe sex") as prevention of transmission with human immuno deficiency virus (hiv) among heterosexual couples, 57 hiv-positive heterosexual patients and their partners if there was one interviewed. Forty-three of the 57 patients were heterosexually infected. Five...

  9. Kritik med objektets forrang

    DEFF Research Database (Denmark)

    Liebst, Lasse Suonperä; Stamer, Naja Buono

    2010-01-01

    Nærværende artikel vil i lyset af den idealistiske epistemologis fremtrædende position i sociologien foreslå, at et fremadrettet brud med denne idealisme kan ske med en tilbagevenden til Theodor W. Adornos negative dialektik. Det frugtbare ved denne særegne dialektik er, hvordan den med en tildel...

  10. Handicap som risikofaktor? Et udviklingspsykopatologisk perspektiv på børn med handicap

    DEFF Research Database (Denmark)

    Dammeyer, Jesper Herup; Bøttcher, Louise

    2010-01-01

    Børn med handicap er generelt i større risiko for at udvikle psykopatologi. Men risikoen for fejludvikling er ikke enkelt forbundet med graden af handicappet. F.eks. oplever børn med hørehandicap næsten fire gange så hyppigt psykosociale vanskeligheder sammenlignet med hørende børn, men det er ikke...... psykopatologi etableres. I artiklen vil vi præsentere en almen model til forståelse af mennesker med handicap og deres udviklingsmuligheder – en handicappsykologisk udviklingsmodel ud fra et dialektisk kultur-historisk perspektiv (Vygotsky, (1924-31) 1993). Ved hjælp af empiriske studier vil vi eksemplificere...... forskellige typiske udviklingsmæssige problemer, der ofte opstår blandt børn med forskellige typer af handicap. At studere børn med handicap og deres psykiske udvikling kan være et vigtigt forskningsmæssigt vindue til at forstå udviklingspsykopatologi generelt....

  11. "Sikker sex" blandt hiv-smittede heteroseksuelle par

    DEFF Research Database (Denmark)

    Weis, N M; Skinnes, L; Vesterdal, B

    1999-01-01

    To investigate the use of condoms ("safe sex") as prevention of transmission with human immuno deficiency virus (hiv) among heterosexual couples, 57 hiv-positive heterosexual patients and their partners if there was one interviewed. Forty-three of the 57 patients were heterosexually infected. Five...... at being given the possibility of talking about problems regarding hiv-transmission and sexuality. In conclusion a discrepancy was found between knowledge about transmission of hiv and the use of condoms among heterosexual couples. Udgivelsesdato: 1999-Jun-14...

  12. Combining two large MRI data sets (AddNeuroMed and ADNI) using multivariate data analysis to distinguish between patients with Alzheimer's disease and healthy controls

    DEFF Research Database (Denmark)

    Westman, Eric; Simmons, Andrew; Muehlboeck, J.-Sebastian

    2010-01-01

    and the high resolution sagital 3D T1w MP-RAGE datasets used for image analysis. Regional segmentation of the brain was carried out using the multi-scale ANIMAL image analysis technique (Automated Non-linear Image Matching and Anatomical Labeling). Cortical thickness measurements were performed using CLASP......NeuroMed cohort as a training set and validating the model with the ADNI cohort resulted in a sensitivity of 78% and specificity of 87%. All three models created showed very similar results. Examples of important variables for discriminating between AD and CTL included temporal lobe grey matter volume, total CSF...... volume and mean cortical thickness. Conclusions: Multivariate data analysis is a powerful tool for distinguishing between different patient groups. The AddNeuroMed, ADNI and combined cohorts showed similar patterns of atrophy and the predictive power was very similar. This demonstrates that the methods...

  13. Nursing identity and patient-centredness in scholarly health services research: a computational text analysis of PubMed abstracts 1986-2013.

    Science.gov (United States)

    Bell, Erica; Campbell, Steve; Goldberg, Lynette R

    2015-01-22

    The most important and contested element of nursing identity may be the patient-centredness of nursing, though this concept is not well-treated in the nursing identity literature. More conceptually-based mapping of nursing identity constructs are needed to help nurses shape their identity. The field of computational text analytics offers new opportunities to scrutinise how growing disciplines such as health services research construct nursing identity. This paper maps the conceptual content of scholarly health services research in PubMed as it relates to the patient-centeredness of nursing. Computational text analytics software was used to analyse all health services abstracts in the database PubMed since 1986. Abstracts were treated as indicative of the content of health services research. The database PubMed was searched for all research papers using the term "service" or "services" in the abstract or keywords for the period 01/01/1986 to 30/06/2013. A total of 234,926 abstracts were obtained. Leximancer software was used in 1) mapping of 4,144,458 instances of 107 concepts; 2) analysis of 106 paired concept co-occurrences for the nursing concept; and 3) sentiment analysis of the nursing concept versus patient, family and community concepts, and clinical concepts. Nursing is constructed within quality assurance or service implementation or workforce development concepts. It is relatively disconnected from patient, family or community care concepts. For those who agree that patient-centredness should be a part of nursing identity in practice, this study suggests that there is a need for development of health services research into both the nature of the caring construct in nursing identity and its expression in practice. More fundamentally, the study raises questions about whether health services research cultures even value the politically popular idea of nurses as patient-centred caregivers and whether they should.

  14. Deriving common comorbidity indices from the MedDRA classification and exploring their performance on key outcomes in patients with rheumatoid arthritis.

    Science.gov (United States)

    Putrik, Polina; Ramiro, Sofia; Lie, Elisabeth; Michaud, Kaleb; Kvamme, Maria K; Keszei, Andras P; Kvien, Tore K; Uhlig, Till; Boonen, Annelies

    2018-03-01

    To develop algorithms for calculating the Rheumatic Diseases Comorbidity Index (RDCI), Charlson-Deyo Index (CDI) and Functional Comorbidity Index (FCI) from the Medical Dictionary for Regulatory Activities (MedDRA), and to assess how these MedDRA-derived indices predict clinical outcomes, utility and health resource utilization (HRU). Two independent researchers linked the preferred terms of the MedDRA classification into the conditions included in the RDCI, the CDI and the FCI. Next, using data from the Norwegian Register-DMARD study (a register of patients with inflammatory joint diseases treated with DMARDs), the explanatory value of these indices was studied in models adjusted for age, gender and DAS28. Model fit statistics were compared in generalized estimating equation (prediction of outcome over time) models using as outcomes: modified HAQ, HAQ, physical and mental component summary of SF-36, SF6D and non-RA related HRU. Among 4126 patients with RA [72% female, mean (s.d.) age 56 (14) years], median (interquartile range) of RDCI at baseline was 0.0 (1.0) [range 0-6], CDI 0.0 (0.0) [0-7] and FCI 0.0 (1.0) [0-6]. All the comorbidity indices were associated with each outcome, and differences in their performance were moderate. The RDCI and FCI performed better on clinical outcomes: modified HAQ and HAQ, hospitalization, physical and mental component summary, and SF6D. Any non-RA related HRU was best predicted by RDCI followed by CDI. An algorithm is now available to compute three commonly used comorbidity indices from MedDRA classification. Indices performed comparably well in predicting a variety of outcomes, with the CDI performing slightly worse when predicting outcomes reflecting functioning and health. © The Author 2017. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  15. Hverdagslivet som uformel omsorgsudøver med en partner med Parkinsons sygdom, – en interviewundersøgelse af kvinders erfaringer med omsorg og livskvalitet

    DEFF Research Database (Denmark)

    Hounsgaard, Lise; Pedersen, B.; Wagner, L.

    2012-01-01

    Formål: At undersøge de levede erfaringer for kvindelige partnere til hjemmeboende patienter med Parkinsons sygdom. Baggrund: Det er kendt, at hverdagslivet med en partner med Parkinsons sygdom indebærer radikale omvæltninger i familien, især for den kvindelige partner. Metode: En fænomenologisk......-hermeneutisk metode blev anvendt. I 2008 gennemførtes interview med kvindelige partnere (N = 10) til hjemmeboende patienter med Parkinsons sygdom. Den franske filosof Ricoeurs teori om fortolkning blev anvendt i analysen af data. Konklusion: Undersøgelsen viste, at livet sammen med en partner med Parkinsons sygdom...

  16. Morgenmadsvaner og overvægt blandt danske skolebørn: hvilken rolle spiller socialgruppe?

    DEFF Research Database (Denmark)

    Fossar Fabritius, Kirstine; Rasmussen, Mette

    2008-01-01

    Introduktion: Forekomsten af overvægt blandt børn og unge er stigende, og i mange industrialiserede lande er overvægt mest udbredt i lave socioøkonomiske grupper. Man har i flere studier påvist, at lav morgenmadsfrekvens øger risikoen for overvægt. Det er dog ukendt, om sammenhængen er ens i alle...... skoleelever i et tilfældigt udsnit af landets skoler i 2002. Deltagerprocenten var 89,3, n = 4.824. Undersøgelsen er det sjette danske bidrag til det internationale forskningsprojekt Health Behaviour in School-aged Children. Socioøkonomisk position blev bestemt ved familiesocialgruppe og morgenmadsfrekvens...

  17. Processeringsoptimering med Canons software

    DEFF Research Database (Denmark)

    Precht, Helle

    2009-01-01

    . Muligheder i software optimering blev studeret i relation til optimal billedkvalitet og kontrol optagelser, for at undersøge om det var muligt at acceptere diagnostisk billedkvalitet og derved tage afsæt i ALARA. Metode og materialer Et kvantitativt eksperimentelt studie baseret på forsøg med teknisk og...... humant fantom. CD Rad fantom anvendes som teknisk fantom, hvor billederne blev analyseret med CD Rad software, og resultatet var en objektiv IQF værdi. Det humane fantom var et lamme pelvis med femur, der via NRPB’ er sammenlignelig med absorptionen ved et femårigt barn. De humane forsøgsbilleder blev...

  18. Virtuelt skrivebord med open office

    DEFF Research Database (Denmark)

    Nielsen, Kurt Gammelgaard

    2009-01-01

    SDUs erfaringer med projektet Port 22: en virtuel platform med Open Office som kontorpakke til studerende.......SDUs erfaringer med projektet Port 22: en virtuel platform med Open Office som kontorpakke til studerende....

  19. Radiojodbehandling af recidiverende hypertyreose hos patienter som tidligere er behandlet for diffus toksisk struma med subtotal strumektomi

    DEFF Research Database (Denmark)

    Vestergaard, H; Laurberg, P

    1993-01-01

    Radioiodine therapy is often employed for treatment of patients with relapse of hyperthyroidism due to Graves' disease, after previous thyroid surgery. Little is known about the outcome of this treatment compared to patients with no previous surgery. A total of 20 patients, who had received...

  20. At leve med osteoporose

    DEFF Research Database (Denmark)

    Hansen, Carrinna; Abrahamsen, Bo; Konradsen, Hanne

    Baggrund: Livet med kronisk sygdom, heriblandt osteoporose, giver anledning til verdensomspændende udfordringer. Osteoporose er ofte en usynlig tilstand før knoglebrud opstår, det er anslået, at hver tredje kvinde og en af fire mænd over 50 år i Europa vil opleve disse typer af knoglebrud og det...... med betydelig sygelighed og dødelighed til følge. At leve med en kronisk tilstand påvirker ofte menneskets livssituation, både specifikt, emotionelt og eksistentielt, hvordan dette opleves er individuelt og det er endnu uklart hvordan osteoporose påvirker den enkeltes livssituation. Formål: At opnå en...... dybere forståelse af livet med osteoporose ved at undersøge ny-diagnosticerede kvinders erfaringer med at leve med osteoporose når medicinsk behandling med henblik på frakturforebyggelse var ordineret. Metode: Et kvalitativt studie med en fænomenologisk-hermeneutisk tilgang, samt et longitudinelt design...

  1. Fremlæggelse af projekt med Epworth søvnighedsskema, opgørelse af data fra 2009-2014: "Prevalence of excessive daytime sleepiness in patients treated with orthognathic surgery"

    DEFF Research Database (Denmark)

    Linderup, Mette Werner

    Fremlæggelse af projekt med Epworth søvnighedsskema, opgørelse af data fra 2009-2014: "Prevalence of excessive daytime sleepiness in patients treated with orthognathic surgery"......Fremlæggelse af projekt med Epworth søvnighedsskema, opgørelse af data fra 2009-2014: "Prevalence of excessive daytime sleepiness in patients treated with orthognathic surgery"...

  2. UL-vejledt anlæggelse af fødeepidural hos patient med torakolumbal skoliose

    DEFF Research Database (Denmark)

    Piosik, Zofia Maria; Helbo-Hansen, Søren; Sprehn, Michael

    2015-01-01

    Providing epidural analgesia in patients with scoliosis may be challenging. We describe ultrasound-guided insertion of an epidural catheter for labour analgesia and a following caesarean section in a patient with a thoracolumbar scoliosis. A well-functioning epidural catheter was easily inserted...... on the first attempt without any need for redirections of the epidural needle. Use of ultrasound imaging to guide epidural needle insertion site and trajectory can be a valuable tool in managing patients with scoliosis....

  3. Medicinsk vs. kirurgisk behandling af svært overvægtige patienter med type 2-diabetes

    DEFF Research Database (Denmark)

    Svane, Maria Saur; Bojsen-Møller, Kirstine Nyvold; Madsbad, Sten

    2016-01-01

    Bariatric surgery induces large and sustainable weight loss in obese patients and improves glycaemic control in patients with Type 2 diabetes. Eleven randomized controlled trials have shown superior glycaemic outcomes after bariatric procedures vs. medical therapy/intensive lifestyle interventions...... in obese patients with Type 2 diabetes. Furthermore, many patients experience remission of Type 2 diabetes after surgery but relapse may occur during follow-up. Data from observational studies show reduced incidence of micro- and macrovascular complications in addition to reduced cardiovascular and total...... mortality after surgery....

  4. Effekten af cellebehandling hos patienter med kronisk iskæmisk hjertesygdom--en gennemgang af et Cochranereview

    DEFF Research Database (Denmark)

    Mathiasen, Anders Bruun; Qayyum, Abbas Ali; Kastrup, Jens

    2015-01-01

    The present Cochrane review included 23 studies randomized placebo-controlled clinical trials with a total of 1,255 patients. The effect of autologous cell therapy versus placebo was examined on left ventricular ejection fraction (LVEF), adverse effects and mortality in patients with chronic isch...

  5. Cytomegalovirus-associeret hæmofagocytosesyndrom og akut nyresvigt hos en patient med kronisk lymfatisk leukæmi

    DEFF Research Database (Denmark)

    Broe, Julie; Lauritzen, Anne Falensteen; Hansen, Per Boye

    2014-01-01

    with haemophagocytic syndrome. The serology was compatible with acute Cytomegalovirus infection. The patient received therapy with ganciclovir, prednisolone and gamma globulin, and the acute renal failure was treated with haemodialysis. The patient responded well to the treatment and was discharged after a month...

  6. Determination of intact parathormone in patients with disorders of calcium metabolism. Maaling av intakt parathormon hos pasienter med kalsiumforstyrrelser

    Energy Technology Data Exchange (ETDEWEB)

    Birkeland, K.I.; Falch, J.A.; Haug, E. (Aker Sykehus, Oslo (Norway)); Gautvik, K.M. (Oslo Univ. (Norway). Inst. for Biokjemi); Gjestvang, F.T. (Vest-Agder Central Hospital, Kristiansand (Norway)); Holst, N. (Tromsoe Regional Hospital (Norway))

    1991-06-01

    The authors have used an immunoradiometric assay (IRMA) to measure intact parathormone (PTH). The serum-levels of PTH followed a log-normal distribution in a population of 85 healthy post-meno-pausal women, with a geometric mean of 1.9 pmol/l and a range of 0.8 to 6.1 pmol/l. The correlation between measurements performed using the IRMA and a radioimmunoassay which measured the C-terminal portion of the PTH molecule was 0.85. It was only the IRMA, however, that could measure subnormal values. Two of 27 patients with primary hyperparathyroidism had PTH-values in the upper reference interval. The rest of the patients had elevated levels. Patient with hypercalcemia due to malignancy had subnormal or low normal PTH values. Half of the patients with hypoparathyroidism had PTH below the limit of detection. 16 refs., 6 figs., 3 tabs.

  7. Med-E-Tel

    National Research Council Canada - National Science Library

    Lievens, Frank; Jordanova, Malina

    2006-01-01

    .... The Med-e-Tel 2006 conference program covered over 130 presentations on topics such as homecare and health management, healthcare challenges, tele-education, eHealth in developing countries, telecardiology...

  8. Slut med skuffeprojekter

    DEFF Research Database (Denmark)

    Holm, Lisbeth; Pedersen, Preben Ulrich; Scheel, Linda Schumann

    2003-01-01

    En etårig tværfaglig uddannelse i projektledelse og evidensbaseret praksis for sundhedspersonale med mellemlange uddannelser har allerede medført konkrete ændringer i klinisk praksis til gavn for patienterne....

  9. PubMed

    CERN Document Server

    PubMed is the National Library of Medicine's search service that provides access to over 10 million citations in MEDLINE, PreMEDLINE, and other related databases, with links to participating online journals.

  10. PubMed

    Data.gov (United States)

    U.S. Department of Health & Human Services — PubMed comprises more than 26 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to...

  11. DailyMed

    Data.gov (United States)

    U.S. Department of Health & Human Services — DailyMed provides high quality information about marketed drugs. This information includes FDA labels (package inserts). This Web site provides health information...

  12. Med-E-Tel

    National Research Council Canada - National Science Library

    Lievens, Frank; Jordanova, Malina

    2006-01-01

    ..., and more. The Med-e-Tel 2006 exhibition showcased products and technologies in the areas of medication compliance, home telehealth and vital sign monitoring, clinical software, electronic medical records...

  13. Personer med handicap

    DEFF Research Database (Denmark)

    Larsen, Brian; Jonassen, Anders Bruun; Høgelund, Jan

    væsentligt i perioden frem til 2006. Det især personer med nedsat hørelse, som er kommet i beskæftigelse. Undersøgelsen er finansieret af Arbejdsmarkedskommissionen. Den bygger på oplysninger om personer med handicap, som havde en målt funktionsnedsættelse i 1995, og personer uden et handicap i 1995. Disse...

  14. Leg med vision

    DEFF Research Database (Denmark)

    Munk, Mette; Bertelsen, Katrine

    2011-01-01

    Bogen henvender sig primært til det pædagogiske personale med målgruppen daginstitutioner. Bogen skal stimulere arbejdet med at gøre bevægelse til en integreret del af kulturen i daginstitutioner - at få det pædagogiske personale til - at sætte ord på og spørgsmålstegn ved deres pædagogiske bevæg...

  15. Cytomegalovirus-associeret hæmofagocytosesyndrom og akut nyresvigt hos en patient med kronisk lymfatisk leukæmi

    DEFF Research Database (Denmark)

    Broe, Julie; Lauritzen, Anne Falensteen; Hansen, Per Boye

    2014-01-01

    with haemophagocytic syndrome. The serology was compatible with acute Cytomegalovirus infection. The patient received therapy with ganciclovir, prednisolone and gamma globulin, and the acute renal failure was treated with haemodialysis. The patient responded well to the treatment and was discharged after a month......A 60-year-old man with chronic lymphocytic leukaemia was admitted to our department with fever and hepatospleno-megaly. Laboratory findings revealed hyperferritinaemia of 40,300 microgram/l and both liver and renal dysfunction. A bone marrow biopsy showed haemophagocytosis consistent...... with normal lever and renal function....

  16. Der mangler undersøgelser af effekten af psykologbehandling til patienter med kræft og depression

    DEFF Research Database (Denmark)

    Johnsen, Anna Thit; Ross, Lone; Guldin, Mai-Britt

    2016-01-01

    Depression is a well-known co-morbidity of cancer. A possible intervention for depression is psychological treatment defined as psychotherapy provided by a psychologist. In this narrative review we investigated the effect of psychological treatment on depression for patients with cancer. Six...... Cochrane reviews of 38 studies investigating psychological or psychosocial interventions were reviewed. One of the 38 studies could not be assessed. None of the included studies investigated psychological treatment for patients who were diagnosed with depression or included because of depression symptoms....

  17. Forebyggelse af infektioner hos patienter, der har kronisk inflammatorisk tarmsygdom og er i behandling med TNF-hæmmere

    DEFF Research Database (Denmark)

    Risager Christensen, Katrine; Steenholdt, Casper

    2014-01-01

    suppression of the immune system. National and international guidelines recommend screening and vaccination for selected infectious agents prior to anti-TNF initiation as well as during ongoing anti-TNF therapy. This review focuses on current available recommendations and discusses physicians’ and patients......Prevention of infections in patients with inflammatory bowel disease during TNF inhibitor treatment Treatment of inflammatory bowel disease with anti-tumour necrosis factor (TNF)-alpha biopharmaceuticals is generally well tolerated, but increases the risk of infections due to globally induced...

  18. Personer med handicap

    DEFF Research Database (Denmark)

    Amilon, Anna; Larsen, Lena Bech; Østergaard, Stine Vernstrøm

    Danmark har været omfattet af FN’s handicapkonvention siden 2009. I tråd med konventionen har den danske handicappolitik til hensigt at skabe lige muligheder for mennesker med handicap og den øvrige befolkning. Denne undersøgelse belyser, i hvilket omfang dette sigte er opfyldt for mennesker med...... handicap i 2016, sammenholdt med den øvrige voksne befolkning. Undersøgelsen sætter fokus på forhold omkring uddannelse, beskæftigelse, forsørgelse, livskvalitet og sundhed, deltagelse og tilgængelighed samt sagsbehandling og diskrimination. Rapporten giver på den måde et bredt billede af, dels hvordan...... forholdene er for mennesker med handicap i 2016, og dels hvordan forholdene har udviklet sig siden den første undersøgelsesrunde i 2012. Undersøgelsen viser, at der er store forskelle på mennesker med og uden handicap, også når det gælder helt fundamentale områder for velfærdssamfundet så som uddannelse og...

  19. Muskelbiopsier hos patienter med fibromyalgi. En undersøgelse baseret på lys- og elektronmikroskopi

    DEFF Research Database (Denmark)

    Drewes, A M; Andreasen, A; Schrøder, H D

    1994-01-01

    of muscle disease. Nevertheless, we subjected biopsies from nine of the patients and five other controls for further ultrastructural evaluations and demonstrated pathologic findings e.g. empty sleeves of basement membrane, many lipofuscin bodies and other degenerative changes. We conclude...

  20. Med handicap i vuggestuen

    DEFF Research Database (Denmark)

    Bendix-Olsen, Kurt

    2017-01-01

    Artiklen udforsker det deltagelsesmæssige råderum, som vuggestuebørn med handicap har i hverdagens inklusionspraksis i ressourcebørnehuse. Ressourcebørnehusenes inklusionsarrangementer er i fokus med henblik på at undersøge, på hvilke måder børn med handicap deltager i hverdagen og får erfaringer...... med og mulighed for at udvikle rådighed. Artiklen fremanalyserer, at inklusionsarrangementer tilvejebringes gennem tre væsensforskellige organiseringer af pædagogisk praksis, der hver på sin måde tilbyder børn med handicap særlige deltagelsesbetingelser: 1) Et kapacitetsfokuseret arrangement 2) Et...... rummende omsorgsarrangement 3) Et repertoireskabende arrangement. De to førstnævnte arrangementer peger på, at handicap er knyttet til binære forståelser af børns behov som almene eller særlige. Hvor de professionelle i det kapacitetsfokuserede arrangement vægtlægger udvikling af barnets kropsfunktioner og...

  1. 3D gait analysis of lower extremity muscle group power in healthy subjects and subacute stroke patients, and task-specific gait interventions in early stroke rehabilitation

    DEFF Research Database (Denmark)

    Brincks, John

    2010-01-01

    Denne ph.d. afhandling omhandler 3D ganganalyse af raske og apopleksipatienter. Formålet med afhandlingen var at estimere referenceværdier for power i et udvalg af underekstremitetens muskelgrupper, samt at estimere ændringer i muskelgruppers power, når ganghastigheden øges blandt raske og apople...

  2. Redefining the MED13L syndrome.

    Science.gov (United States)

    Adegbola, Abidemi; Musante, Luciana; Callewaert, Bert; Maciel, Patricia; Hu, Hao; Isidor, Bertrand; Picker-Minh, Sylvie; Le Caignec, Cedric; Delle Chiaie, Barbara; Vanakker, Olivier; Menten, Björn; Dheedene, Annelies; Bockaert, Nele; Roelens, Filip; Decaestecker, Karin; Silva, João; Soares, Gabriela; Lopes, Fátima; Najmabadi, Hossein; Kahrizi, Kimia; Cox, Gerald F; Angus, Steven P; Staropoli, John F; Fischer, Ute; Suckow, Vanessa; Bartsch, Oliver; Chess, Andrew; Ropers, Hans-Hilger; Wienker, Thomas F; Hübner, Christoph; Kaindl, Angela M; Kalscheuer, Vera M

    2015-10-01

    Congenital cardiac and neurodevelopmental deficits have been recently linked to the mediator complex subunit 13-like protein MED13L, a subunit of the CDK8-associated mediator complex that functions in transcriptional regulation through DNA-binding transcription factors and RNA polymerase II. Heterozygous MED13L variants cause transposition of the great arteries and intellectual disability (ID). Here, we report eight patients with predominantly novel MED13L variants who lack such complex congenital heart malformations. Rather, they depict a syndromic form of ID characterized by facial dysmorphism, ID, speech impairment, motor developmental delay with muscular hypotonia and behavioral difficulties. We thereby define a novel syndrome and significantly broaden the clinical spectrum associated with MED13L variants. A prominent feature of the MED13L neurocognitive presentation is profound language impairment, often in combination with articulatory deficits.

  3. MED COMMITTEE STRUCTURE

    Science.gov (United States)

    It is beneficial to share good Diversity-related practices with other NHEERL Divisions. Sharing of this information will help MED showcase the many activities that are in place for Diversity that we are using to help us become a level 4 organization.

  4. Professionalisme med innovativt potentiale

    DEFF Research Database (Denmark)

    Nielsen, Inger Marie

    To teoretiske sværvægtere bliver koblet sammen i Inger Marie Larsen-Nielsen arbejdspapir om professionalisme med innovativt potentiale. De to teoretikere er læringsteoretikeren John Dewey og socialpsykologen Georg Herbert Mead, som er sat sammen i en teoretisk forståelsesramme omkring professionel...

  5. Answers to questions posed during daily patient care are more likely to be answered by UpToDate than PubMed.

    NARCIS (Netherlands)

    Hoogendam, A.; Stalenhoef, A.F.H.; Vries Robbe, P.F. de; Overbeke, A.J.P.M.

    2008-01-01

    BACKGROUND: UpToDate and PubMed are popular sources for medical information. Data regarding the efficiency of PubMed and UpToDate in daily medical care are lacking. OBJECTIVE: The purpose of this observational study was to describe the percentage of answers retrieved by these information sources,

  6. Letter to the Editor: Orthostatic Reactivity in Patients with Ischemic Stroke in the Chronic Period. OA Maced J Med Sci. http://dx.doi.org/10.3889/oamjms.2015.090

    OpenAIRE

    Vasileva, Danche

    2015-01-01

    I am writing you about our publication Orthostatic Reactivity in Patients with Ischemic Stroke in the Chronic Period, published OnlineFirst in OA Maced J Med Sci on August 01, 2015 [1]. Tables and Figures are not adequate for this publication, because they are from the previously published paper Orthostatic Reactivity in Patients with Diabetic Neuropathy. OA Maced J Med Sci. 2014 Jun 15; 2(2):244-248 [2]. I am sending you correct Tables and Figures and ask you to correct them, if poss...

  7. Kontrol af patienter med levertraumer

    DEFF Research Database (Denmark)

    Osterballe, Lene; Helgstrand, Frederik; Hillingsø, Jens

    2014-01-01

    Development of a hepatic pseudoaneurysm (HPA) is a well-known, yet rare complication after liver trauma. We found 135 cases reported in the literature since 1965. Ruptured HPAs may have severe consequences with sudden massive haemorrhage and death. A clear strategy towards diagnosis and management...... of HPA post liver trauma is needed and outlined in this paper. We recommend early detection and definitive treatment before enlargement and rupture....

  8. Akupunktur til patienten med kvalme og opkastning i forbindelse med kemoterapi - er der evidens for dette?

    DEFF Research Database (Denmark)

    Pedersen, Birgith; Sørensen, Lene Bundgaard; Stricker, Lisbeth

    2008-01-01

      Patienter, der får kemoterapi med højemetogene stoffer lider stadig af kvalme og opkastning trods understøttende behandling med moderne antieemtika som 5HT3-antagonister eksempelvis ondansetron. Akupunkturstimulation anvendes for flere lidelser i sundhedsvæsenet og det undersøges om der er evid...

  9. Stjerneroller med stort K

    DEFF Research Database (Denmark)

    Redvall, Eva Novrup

    2017-01-01

    Der er langt mellem de spændende roller til kvinder over 40 i amerikansk film og tv. Det har flere kvindelige filmstjerner før og nu arbejdet aktivt på at ændre ved at søsætte egne projekter. To vellykkede eksempler på det kan for tiden ses på HBO i 'Big Little Lies' med Reese Witherspoon og Nico...

  10. Farlig sex med engle

    DEFF Research Database (Denmark)

    Mejrup, Kristian

    2013-01-01

    De fleste af os tænker ikke på engle som kønnede væsner med en seksualitet, og selv om vi er i stand til at acceptere engle i alle mulige afskygninger, fra juletræets tyksakker i glitrende guld til frygtindgydende skikkelser i de bibelske skrifter, så er vi tilbøjelig til at ignorere spørgsmålet ...

  11. At lede med latter

    DEFF Research Database (Denmark)

    Møller, Mette

    2014-01-01

    "Det sagde hun også i går!" Platte vitser, der lægger op til den karakteristiske 'bodom-tchi'-trommelyd, behøver ikke være lederens eneste forsøg på at udvise humoristisk sans på talerstolen. For humor kan være meget andet og gøre meget mere for lederen end at score billige point med en spontan s...

  12. Monitorering af fysisk aktivitetsniveau (MOAN) hos indlagte patienter på geriatrisk afdeling - forsøgsprotokol

    DEFF Research Database (Denmark)

    Villumsen, Morten; Jørgensen, Martin Grønbech; Andreasen, Jane

    genvinder disse igen.(1) Der er desuden god dokumentation for at også ældre patienter med demens kan forbedre funktionsniveau ved træning.(2) Særligt styrketræning af underekstremiteterne med høj intensitet, har vist sig at være effektivt. Hvilket blandt andet har kunnet registreres med ”Timed up and go...... udskrivelse? 2. At undersøge hvilken betydning tiden stående/gående har for ændringen i Barthel Index under indlæggelsen. Metode: Undersøgelsen gennemføres som et observationssstudie af aktivitetsniveau fra indlæggelse til udskrivelse for patienter indlagt på geriatrisk afdeling Aalborg sygehus. Timed up...... and Go (TUG), rejse-sætte sig testen og Barthel score registreres for alle patienter ved indlæggelse og udskrivelse. Øvrige oplysninger vedrørende alder, køn, vægt, højde, demens, depression, årsag til indlæggelse, boligform, og pårørende indhentes fra journalen. Primær outcome for undersøgelsen er den...

  13. "MedTRIS" (Medical Triage and Registration Informatics System): A Web-based Client Server System for the Registration of Patients Being Treated in First Aid Posts at Public Events and Mass Gatherings.

    Science.gov (United States)

    Gogaert, Stefan; Vande Veegaete, Axel; Scholliers, Annelies; Vandekerckhove, Philippe

    2016-10-01

    First aid (FA) services are provisioned on-site as a preventive measure at most public events. In Flanders, Belgium, the Belgian Red Cross-Flanders (BRCF) is the major provider of these FA services with volunteers being deployed at approximately 10,000 public events annually. The BRCF has systematically registered information on the patients being treated in FA posts at major events and mass gatherings during the last 10 years. This information has been collected in a web-based client server system called "MedTRIS" (Medical Triage and Registration Informatics System). MedTRIS contains data on more than 200,000 patients at 335 mass events. This report describes the MedTRIS architecture, the data collected, and how the system operates in the field. This database consolidates different types of information with regards to FA interventions in a standardized way for a variety of public events. MedTRIS allows close monitoring in "real time" of the situation at mass gatherings and immediate intervention, when necessary; allows more accurate prediction of resources needed; allows to validate conceptual and predictive models for medical resources at (mass) public events; and can contribute to the definition of a standardized minimum data set (MDS) for mass-gathering health research and evaluation. Gogaert S , Vande veegaete A , Scholliers A , Vandekerckhove P . "MedTRIS" (Medical Triage and Registration Informatics System): a web-based client server system for the registration of patients being treated in first aid posts at public events and mass gatherings. Prehosp Disaster Med. 2016;31(5):557-562.

  14. Fra inaktiv til regelmæssig motionsløber - en kvalitativ interviewundersøgelse af succesfuld adfærdsændring blandt motionsløbere

    DEFF Research Database (Denmark)

    Løite, Vibeke Brinkmann; Lund-Cramer, Pernille

    2014-01-01

    er baseret på filosofisk-hermeneutisk fortolkning af individuelle, semi-strukturerede interviews. Ti informanter blev selekteret strategisk blandt deltagere i forskningsprojektet DANO-RUN (7 mænd, 3 kvinder, gennemsnitsalder 41,5 år). Interviewguiden blev udarbejdet med afsæt i Theory of Planned...... Behavior (TPB) og The Transtheoretical Model (TTM). Efterfølgende kodning og analyse af interviewene blev udført i analysesoftwaren NVivo 10. Resultater: TPB: Informanterne oplevede en erfaringsbaseret ændring i affective beliefs knyttet til løbeadfærden, som medvirkede til, at intentionen for at løbe...... of change anvendtes i størst omfang på action stage, hvorimod behavioral processes of change primært anvendtes på maintenance stage. Informanterne tillagde alle forpligtigelsen overfor DANO-RUN at have afgørende motiverende betydning. Konklusion: Denne undersøgelse viste, at individuelle faktorer i form af...

  15. ALKOHOL MED MLADOSTNIKI

    OpenAIRE

    Blazinšek, Valentina

    2011-01-01

    Uporaba alkohola je ena od oblik tveganega vedenja, s katero mladostnik išče razumevanje in odobravanje predvsem v družbi lastne generacije. Uporablja jo zlasti pod vplivom pritiskov z dveh strani: sveta odraslih in sveta vrstnikov, v katerem pogosto veljajo drugačna pravila, vrednote, oblike vedenja in komuniciranja, kot jih zapovedujejo odrasli. Zato je poseganje po alkoholu problem, ki mu veliko držav posveča posebno pozornost. Med številnimi zdravstvenimi problemi, ki tako ali drugače pri...

  16. Undernäring hos äldre patienter med höftfraktur: orsaker och omvårdnadsåtgärder : En litteraturöversikt

    OpenAIRE

    Stridbo, Andreas; Karlsson-Goth, Amanda

    2013-01-01

    Syfte: Syftet med denna litteraturöversikt var att beskriva orsaker till undernäring hos äldre patienter med höftfraktur i det postoperativa skedet, samt vilka omvårdnadsåtgärder som kan användas för att förebygga undernäring. Metod: Studien genomfördes som en litteraturöversikt och artiklarna söktes via databaserna PubMed och CINAHL. 15 artiklar hittades och ligger till grund för resultatet. 14 av dessa var av kvantitativ ansats och en var kvalitativ. Resultat: Orsaker till undernäring posto...

  17. Giver specifik fodtræning og indlæg en yderligere effekt sammenlignet med et standard knæfokuseret træningsforløb for patienter med patellofemoral smertesyndrom?

    DEFF Research Database (Denmark)

    Mølgaard, Carsten; Andreasen, Jane; Christensen, Marianne

    tilstrækkelig evidens for en overbevisende effekt af fod- og knæortoser i behandlingen af PFPS patienter. Formål: At undersøge om en kombination af specifik fodtræning og indlæg kan forbedre effekten af et standard træningsregime i behandlingen af patellofemorale smerte syndrom (PFPS). Materiale og metode...

  18. MedPAC Data Book

    Data.gov (United States)

    U.S. Department of Health & Human Services — MedPACs Data Book is the result of discussions with congressional staff members regarding ways that MedPAC can better support them. Some of the information it...

  19. Povezave med razjedo zaradi pritiska in ohranjanjem integritete kože pacienta v intenzivni zdravstveni obravnavi: literature review: pregled literature: Relations between pressure ulcer and patient skin integrity maintenance in intensive care:

    OpenAIRE

    Emeđi, Dragica; Skela-Savič, Brigita

    2015-01-01

    Introduction: The research aims to demonstrate the multidimensional needs and potential high-risk factors for developing pressure ulcer in adult patients in the intensive care. Methods: The analysis and synthesis of the evidence review from the EMERALD, CINAHL, PubMed, and ProQuest database were employed in the research. The search terms used were: "quality of care", "pressure ulcer", "prevention and treatment of pressure ulcers", "skin integrity critical care patients". The filtering search ...

  20. Alvorlige personskader ved færdselsuheld med indregistrerede motorkøretøjer blandt indbyggere i Odense Kommune 1990-1999

    DEFF Research Database (Denmark)

    Faergemann, Christian; Larsen, Lars Binderup

    2002-01-01

    INTRODUCTION: Since 1990, the number of persons treated at the Odense University Hospital for injuries following road traffic with registered motor vehicles has increased. In this study we wanted to examine if the increase included an increase in more severe injuries. MATERIAL AND METHODS......: The study included all inhabitants in the Municipality of Odense treated at the Odense University Hospital for more severe injuries (MAIS > or = 3) following road traffic accidents as drivers or passengers in registered motor vehicles during the period January 1st 1990 to December 31st 1999. RESULTS: 241...... severe injuries following road traffic accidents with registered motor vehicles was constant during the period. Accidents involving young men and single accidents were dominating. Prophylactic measures should be aimed at this type of road users....

  1. Rygevaner blandt 11-15 årige i 1988. Undersøgelse af rygevaner og deres sammenhaeng med sociale baggrundsfaktorer, helbred, trivsel og socialt netvaerk

    DEFF Research Database (Denmark)

    Holstein, B E; Ito, H; Due, P

    1990-01-01

    A total of 1,671 schoolchildren aged 11, 13 and 15 years answered an anonymous questionnaire in 1988 on their social backgrounds, social networks, health, life satisfaction and health behaviour. The proportions who had tried to smoke were 24%, 51%, and 66% in the three age groups; the proportions...

  2. Rygevaner blandt 11-15 årige i 1988. Undersøgelse af rygevaner og deres sammenhaeng med sociale baggrundsfaktorer, helbred, trivsel og socialt netvaerk

    DEFF Research Database (Denmark)

    Holstein, B E; Ito, H; Due, P

    1990-01-01

    A total of 1,671 schoolchildren aged 11, 13 and 15 years answered an anonymous questionnaire in 1988 on their social backgrounds, social networks, health, life satisfaction and health behaviour. The proportions who had tried to smoke were 24%, 51%, and 66% in the three age groups; the proportions...... and by the number of smokers at home. Smoking was associated with poor health, fatigue, school tiredness, school performance below the average, frequent contacts with friends outside school and at night, difficulties in discussion with parents, ease in discussions with friends, and with having close friends...

  3. Dødelighed--selvmord og naturlig død--blandt deprimerede patienter. Relationen til depressionstype

    DEFF Research Database (Denmark)

    Hansen, P E; Wang, A G; Kragh-Sørensen, P

    1994-01-01

    of comparing the antidepressant effect of newer selective serotonin reuptake inhibitors (SSRI), citalopram and paroxetine, with that of the tricyclic antidepressant drug, clomipramine. Diagnostic classification according to the Newcastle-I Scale into endogenous and nonendogenous depression was performed...... of suicides in the nonendogenous group largely occurred within the first year of observation. No association was found between response to the antidepressant treatment in the trial and the suicide risk during the first three years of observation. Udgivelsesdato: 1994-Nov-28...

  4. Psykosocial støtte til pårørende til patienter med primær malign hjerne-tumor i et palliativt forløb

    DEFF Research Database (Denmark)

    Fuhlendorff, Britta

    og belastende at være pårørende til et menneske med hjernetumor. Dette stiller krav til de sundhedsprofessionelle om at kunne støtte og afhjælpe denne belastning for at leve op til WHO’s målsætning for den palliative indsats: ”at fremme livskvaliteten hos patienter og familier, som står over for de...

  5. A marvel of precision: MedAustron

    CERN Multimedia

    Anaïs Schaeffer

    2013-01-01

    MedAustron, which is currently being built in Austria, will be one of the most advanced centres for ion beam therapy and research in Europe. It is based on the same design as the Italian National Centre for Oncological Hadrontherapy (CNAO), which in turn is based on the CERN-led Proton Ion Medical Machine Study (PIMMS). MedAustron should welcome its first patient at the end of 2015.   Layout of the MedAustron accelerator complex.  With three ion-sources, a linac, a synchrotron and four irradiation rooms (see picture), MedAustron is a huge accelerator complex. Among other equipment, it comprises 300 magnets of 30 different types, all designed at CERN but produced at different sites: “We are working with five main suppliers from Europe and Russia,” explains Thomas Zickler, leader of the MedAustron magnet group. “All the magnets come to CERN to undergo a series of strict acceptance tests.” From the interfaces, to the electrical insulation, the co...

  6. Værdier med mening

    DEFF Research Database (Denmark)

    Gørtz, Kim

    Bogen handler om at frigøre arbejdet med værdier fra tekniske og pragmatiske operationer - og tilsigter herved at øge forståelsen for hvilke grundlæggende fejl, udfordringer og faldgruber, der typisk forekommer i forbindelse med værdiarbejdet, personligt såvel som organisatorisk....

  7. Measurement properties of the Danish version of the Illness Perception Questionnaire

    DEFF Research Database (Denmark)

    Hvidberg, Line; Flytkjaer Jensen, Line; Fischer Pedersen A, A

    2014-01-01

    symptomer. En konfirmatorisk faktoranalyse viste, at den danske modificerede version af IPQ-R ikke var fuldstændig kompatibel med den originale faktorstruktur. Ved hjælp af en eksplorativ faktoranalyse fandtes dog en faktorstruktur, der lignede den originale. Konklusionen blev, at den modificerede udgave af...... IPQ-R kan anvendes til at undersøge symptomforestillinger blandt danske patienter med tarmkræft, dog skal blandt andet skalaerne omhandlende kontrol anvendes med forbehold....

  8. Mikrokimærisme og kræft blandt kvinder

    DEFF Research Database (Denmark)

    Hansen, Katrine Pedersbæk; Kamper-Jørgensen, Mads

    2017-01-01

    Ifølge græsk mytologi var Kimære en uhyrlig hybridmellem en løvinde, en slange og en ged. I moderne videnskab betegner en kimære en organisme, der består af celler eller organer med forskelligt ophav. Mikrokimærisme betegner en tilstand, hvor der i en vært eksisterer små mængder af celler, som...

  9. Behandling med implanterbar defibrillator

    DEFF Research Database (Denmark)

    Roseva-Nielsen, Natasha G; Svendsen, Jesper Hastrup

    2003-01-01

    About 20 years ago the first patient received an implantable cardioverter defibrillator (ICD), and since then the number of implants have increased dramatically. The ICD can terminate ventricular fibrillation and ventricular tachycardia. Studies of secondary prophylaxis show that ICD treatment can...

  10. Trikuspidalklapendocarditis med pneumokokker

    DEFF Research Database (Denmark)

    Rasmussen, S; Talleruphuus, U; Wandall, Johan

    1995-01-01

    Endocarditis caused by pneumococci is a rare disease and cases that only affect the tricuspid valve represent less than 1% of all cases of endocarditis. A case presenting with a primary pneumonia and septicaemia is described. Due to persistent fever and the occurrence of a cardiac murmur...... echocardiography was done and demonstrated vegetations on the tricuspid valve. The course was complicated with septic pulmonary emboli before the patient recovered. Endocarditis with pneumococci may occur as a complication to a primary pneumonia and underestimation of the frequency with which it occurs...

  11. CAM on PubMed

    Science.gov (United States)

    ... PubMed provides access to citations from the MEDLINE database and additional life science journals. It also includes links to many full-text articles at journal Web sites and other related Web resources. Sample Searches ...

  12. Further confirmation of the MED13L haploinsufficiency syndrome

    NARCIS (Netherlands)

    van Haelst, M.M.; Monroe, G.R.; Duran, K.J.; van Binsbergen, E.; Breur, J.M.P.J.; Giltay, J.C.; van Haaften, G.W.

    MED13L haploinsufficiency syndrome has been described in two patients and is characterized by moderate intellectual disability (ID), conotruncal heart defects, facial abnormalities and hypotonia. Missense mutations in MED13L are linked to transposition of the great arteries and non-syndromal

  13. Training health care teams in intercultural communication and patient safety

    DEFF Research Database (Denmark)

    Odgaard, Eva; Pedersen, Lise

    2017-01-01

    Patientsikkerhed gennem effektiv kommunikation Patientsikkerhed i sundhedsvæsnet afhænger blandt andre faktorer af effektiv kommunikation mellem personale og patienter og mellem sundhedspersonale indbyrdes. Effektiv kommunikation udfordres i situationer, hvor der opstår kulturelle og eller...

  14. Nyretransplantation med levende donor

    DEFF Research Database (Denmark)

    Kamper, A L; Løkkegaard, H; Rasmussen, F

    2000-01-01

    In recent years transplantation from living donors has accounted for 25-30% of all kidney transplants in Denmark corresponding to 40-45 per year. Most of these living donors are parents or siblings, although internationally an increasing number are unrelated donors. Donor nephrectomy is associate...... in cadaver transplantation. The ethical and psychological aspects related to transplantation from a living donor are complex and need to be carefully evaluated when this treatment is offered to the patients.......In recent years transplantation from living donors has accounted for 25-30% of all kidney transplants in Denmark corresponding to 40-45 per year. Most of these living donors are parents or siblings, although internationally an increasing number are unrelated donors. Donor nephrectomy is associated...... with only few complications. The long-term outcome for kidney donors is good without increase in mortality or risk for development of hypertension and renal failure; proteinuria may be seen. Living kidney transplantation is the optimal treatment of end-stage renal disease with better graft survival than...

  15. Opbygning af alliance. Musikterapi med en teenagepige fra børnepsykiatrien med diagnosen infantil autisme

    Directory of Open Access Journals (Sweden)

    Inge Nygaard Pedersen

    2003-03-01

    Full Text Available Denne artikel er et forsøg på at bringe læseren med ind i atmosfæren, i oplevelsen og overvejelserne i forbindelse med opstart på et musikterapiforløb med en patient, som er meget svær at få kontakt med. Den er skrevet i et detaljerigt praksisnært sprog og har på én gang til for mål at starte på dokumentation af musikterapeutisk arbejde i børnepsykiatrien på musikterapiklinikken,APS og at formidle de mange facetter i et allianceopbyggende arbejde med en meget kontaktsvag patient. Artiklen beskriver prøveforløb og første del af et behandlingsforløb og er bygget op, således at praksisbeskrivelser fra enkelte sessioner efterfølges af teoretiske overvejelser over klinisk praksis. Beskrivelsen af prøveforløbet danner samtidig udgangspunkt for en artikel af min kollega Ulla Holck, hvori hun diskuterer musikterapiens appel og virkefelt ud fra et interaktionsteoretisk perspektiv.

  16. Med det sociale som designmateriale

    DEFF Research Database (Denmark)

    Brandt, Eva; Binder, Thomas

    2016-01-01

    Samarbejde, samskabelse og social nysgerrighed er i dag en præmis for den nyskabende designer. Det sociale er det nye designmateriale som unge designere giver sig i kast med når f.eks. Emmy Linde samarbejder med plejehjemsbeboere, deres pårørende, plejepersonale og fysioterapeuter for at designe...... inviterer til aktivitet og ’wayfinding’ gradvist tog form gennem afprøvning og dialog. Denne designpraksis kaldes ’kollaborativ design’ eller i kort form ’codesign’. Men hvad er godt design med ’det sociale’ som designmateriale? Og hvad er vedkommende samtidsdesign når designere og designstuderende slipper...... de faste holdepunkter i studiokulturen og den kanon for dansk design som mange ser det som en vigtig opgave at være kurator for? Det er nogle af de spørgsmål som kapitlet kredse om....

  17. To tilfælde af takotsubo-kardiomyopati hos patienter behandlet med høje doser inhalerede beta-2-agonister

    DEFF Research Database (Denmark)

    Thomsen, Camilla Fjord; Jeppesen, Jørgen Lykke; Stride, Nis Ottesen

    2016-01-01

    Takotsubo cardiomyopathy (TCM) is characterised by reversible left ventricular dysfunction in patients presenting with acute coronary syndrome (ACS). TCM is considered multifactorial, and the repetitive exposure to inhaled beta-2-agonists has been suspected to induce TCM in predisposed individuals....... We report two cases of TCM in female patients presenting with ACS both exposed to inhaled beta-2-agonists. Eccocardiography revealed apical ballooning and reduced left ventricular function. Coronary angiography was with no significant stenosis. Both patients recovered by anticongestive treatment....

  18. Ud at se med Erasmus

    DEFF Research Database (Denmark)

    Frandsen, Pernille

    2009-01-01

    Få lidt luft under vingerne, kom ud at møde udenlandske kolleger og se, hvordan man også kan lave uddannelsesbibliotek. Med begejstring fortæller tre bibliotekarer om deres oplevelser i det store udland – alt sammen finansieret af Erasmus.......Få lidt luft under vingerne, kom ud at møde udenlandske kolleger og se, hvordan man også kan lave uddannelsesbibliotek. Med begejstring fortæller tre bibliotekarer om deres oplevelser i det store udland – alt sammen finansieret af Erasmus....

  19. Implementation of a web-based tool for patient medication self-management: the Medication Self-titration Evaluation Programme (Med-STEP for blood pressure control

    Directory of Open Access Journals (Sweden)

    Richard W Grant

    2013-12-01

    Full Text Available Background Informatics tools may help support hypertension management.Objective To design, implement and evaluate a web-based system for patient anti-hypertensive medication self-titration.Methods Study stages included: six focus groups (50 patients to identify barriers/facilitators to patient medication self-titration, software design informed by qualitative analysis of focus group responses and a six-month single-arm pilot study (20 patients to assess implementation feasibility.Results Focus groups emphasised patient need to feel confident that their own primary care providers were directly involved and approved of the titration protocol. Physicians required 3.3 ± 2.8 minutes/patient to create individualised six-step medication pathways for once-monthly blood pressure evaluations. Pilot participants (mean age of 51.5 ± 11 years, 45% women, mean baseline blood pressure 139/84 ± 12.2/7.5 mmHg had five medication increases, two non-adherence self-reports, 52months not requiring medication changes, 24 skipped months and 17 months with no evaluations due to technical issues. Four pilot patients dropped out before study completion. From baseline to study completion, blood pressure decreased among the 16 patients remaining in the study (8.0/4.7 mmHg, p = 0.03 for both systolic and diastolic pressures.Conclusions Lessons learned included the benefit of qualitative patient analysis prior to system development and the feasibility of physicians designing individual treatment pathways. Any potential clinical benefits were offset by technical problems, the tendency for patients to skip their monthly self-evaluations and drop outs. To be more widely adopted such systems must effectively generalise to a wider range of patients and be integrated into clinical workflow.

  20. Førtidspension til patienter med syndromesygdomme. En registerundersøgelse på basis of oplysninger fra Den Sociale Ankestyrelse

    DEFF Research Database (Denmark)

    Stenager, Elsebeth N; Svendsen, Morten Aagren; Stenager, Egon

    2003-01-01

    the incidence of patients granted disability retirement pension with the diagnoses whiplash, fibromyalgia, chronic pain disorder, chronic fatigue syndromee, chronic strain syndromee, and pelvic syndromee. 2) To estimate changes in the level of pension granted to patients with syndromee diagnosis. 3) To compare...

  1. Recidiverende tilfælde af spinocellulær karcinom i necrobiosis lipoidica-sår hos en patient med diabetes

    DEFF Research Database (Denmark)

    Kolovics, Judit; Mattes, Liuba Penova; Andersen, Klaus Ejner

    2015-01-01

    The development of squamous cell carcinoma in chronic and/or non-healing ulcers associated with necrobiosis lipoidica (NL) is rare, but should be considered in diabetic patients. NL is a non-infectious granulomatous degenerative skin disease. The prevalence of NL in diabetic patients is estimated...

  2. The diagnosis of thymoma and thymic atrophy in patients with myasthenia gravis; Dignostikk av tymom og thymusatrofi hos pasienter med myasthenia gravis

    Energy Technology Data Exchange (ETDEWEB)

    Sund, K.K.; Skeie, G.O.; Gilhus, N.E.; Aarli, J.A.; Varhaug, J.E. [Haukeland Sykehus, Bergen (Norway)

    1997-11-01

    The authors have compared clinical, immunological and radiological data in 20 patients with myasthenia gravis and thymoma and in 21 patients with myasthenia gravis and thymic atrophy. The median age at onset was 54 years in the thymoma group and 63 years in the thymic atrophy group. The severity of the disease was similar in the two groups, and there was no significant difference in the concentration of acetylcholine receptor antibodies. CA antibodies were demonstrated in 17/20 thymoma patients and in 6/21 with thymic atrophy, while 19/20 thymoma patients had antibodies to titin, compared with 9/21 among those with thymic atrophy. The diagnosis and treatment of patients with myasthenia gravis is based upon an evaluation of clinical, immunological and radiological data. 28 refs., 2 tabs.

  3. Informationsledelse med mindset-map

    DEFF Research Database (Denmark)

    Brodersen, Lars

    i ring og skaber splid frem for samarbejde, og om indholdet er opstået på tilfældigheder. Med informationsledelse får du kompetencer til at skabe meningsfuld information ved at holde brugerfokus hele vejen gennem projektet og reducere kompleksiteten, hvad enten du skal bage kage, bygge motorveje...

  4. Fotofilm om musikterapi med flygtninge

    DEFF Research Database (Denmark)

    Lindvang, Charlotte

    2016-01-01

    mennesker fra andre kulturer. Musikken er et universelt sprog og musik kan derfor være et mødested. Musikterapi i forbindelse med voksne traumatiserede flygtninge giver god mening, fordi musikken giver mulighed for at regulere den stress som sidder i krop og sind. Flygtningebørn kan have svært ved at udtale...

  5. Identifiering av upplevelse av smärta hos patienter med cancer som får palliativ vård : en litteraturstudie

    OpenAIRE

    Ax, Anna-Karin; Johansson, Erica

    2006-01-01

    One third of all Swedish people will suffer in cancer. Pain is a common symptom in cancer patients. The pain is subjective and includes several dimensions. The dimensions of pain are the physical, psychological, social and spiritual. This is a literature review and the aim with this study was to identify the pain experience in patients with cancer receiving palliative care. Nineteen articles were analysed. The result shows that the physical pain was experienced as chronicle or episodic pain. ...

  6. Recidiverende tilfælde af spinocellulær karcinom i necrobiosis lipoidica-sår hos en patient med diabetes

    DEFF Research Database (Denmark)

    Kolovics, Judit; Mattes, Liuba Penova; Andersen, Klaus Ejner

    2015-01-01

    The development of squamous cell carcinoma in chronic and/or non-healing ulcers associated with necrobiosis lipoidica (NL) is rare, but should be considered in diabetic patients. NL is a non-infectious granulomatous degenerative skin disease. The prevalence of NL in diabetic patients is estimated...... to 0,3-1,2%. Awareness of malignant transformation potential within a plaque of NL is crucial for early diagnosis and easy radical treatment. A case from our outpatient diabetes clinic is presented....

  7. Medicinudløst hudkløe, sår og blærer hos tre patienter med pseudoporfyri

    DEFF Research Database (Denmark)

    Þorsteinsdóttir, Sunna; Velander, Marie Juul; Bygum, Anette

    2015-01-01

    Pseudoporphyria cutanea tarda is a well described bullous skin disorder which resembles porphyria cutanea tarda. However, the levels of porphyrins in plasma, urine and faeces are normal. We present three cases of patients with classical symptoms of pseudoporhyria. Two of the patients developed ps...... pseudoporphyria after the combination of intensive sunbathing and medications well known to cause pseudoporphyria. The third case received haemodialysis and furosemide....

  8. Medicinudløst hudkløe, sår og blærer hos tre patienter med pseudoporfyri

    DEFF Research Database (Denmark)

    Thorsteinsdóttir, Sunna; Velander, Marie Juul; Bygum, Anette

    2015-01-01

    Pseudoporphyria cutanea tarda is a well described bullous skin disorder which resembles porphyria cutanea tarda. However, the levels of porphyrins in plasma, urine and faeces are normal. We present three cases of patients with classical symptoms of pseudoporphyria. Two of the patients developed p...... pseudoporphyria after the combination of intensive sunbathing and medications well known to cause pseudoporphyria. The third case received haemodialysis and furosemide....

  9. Juvenil polypose-syndrom og hereditær hæmoragisk telangiektasi hos en patient med SMAD4-mutation

    DEFF Research Database (Denmark)

    Jelsig, Anne Marie; Tørring, Pernille Mathiesen; Wikman, Friedrik

    2014-01-01

    Germ line mutations in SMAD4 can cause both juvenile polyposis syndrome and hereditary haemorrhagic telangiectasia syndrome. In this case we present a 37-year-old man with a frameshift mutation in SMAD4. The patient had multiple polyps in the gastrointestinal tract and was diagnosed with colon ca...... cancer at the age of 21 and gastro-oesophageal junction cancer at the age of 37. Furthermore the patient had telangiectasias and recurrent epistaxis....

  10. Usikkert om vægtreducerende kost påvirker risikoen for tidlig død hos patienter med hypertension--en gennemgang af et Cochranereview

    DEFF Research Database (Denmark)

    Køster-Rasmussen, Rasmus; Simonsen, Mette Kildevæld; de Fine Olivarius, Niels

    2012-01-01

    The Cochrane review "Long-term effects of weight-reducing diets in hypertensive patients" fails to evaluate the primary outcomes of mortality and morbidity. It is uncertain whether weight loss in general reduces the risk of cardiovascular disease and death as the relation between intentional weight...

  11. Præhospital behandling af svært tilskadekomne patienter med fokus på damage control-kirurgi

    DEFF Research Database (Denmark)

    Sørensen, Anne Marie; Larsen, Claus Falck; Steinmetz, Jacob

    2011-01-01

    The majority of patients undergoing damage control surgery initially receive prehospital treatment. Bleeding causes 40% of trauma deaths, half of which happen in the prehospital setting. Future research and improved treatment before hospital admission should focus on control of the bleeding, avoi...

  12. Præhospital behandling af svært tilskadekomne patienter med fokus på damage control-kirurgi

    DEFF Research Database (Denmark)

    Sørensen, Anne Marie; Larsen, Claus Falck; Steinmetz, Jacob

    2011-01-01

    The majority of patients undergoing damage control surgery initially receive prehospital treatment. Bleeding causes 40% of trauma deaths, half of which happen in the prehospital setting. Future research and improved treatment before hospital admission should focus on control of the bleeding...

  13. Hyppige samtaler kan måske hjælpe ved svært nedsat adhærens hos belastede patienter med hiv

    DEFF Research Database (Denmark)

    Barfod, Toke Seierøe; Bergstedt, Winnie

    2013-01-01

    This pilot study investigates the feasibility and effect of an intervention based on coaching and directly observed therapy (DOT), aimed at patients who are HIV-positive and have massive adherence problems and treatment failure. Participants were followed six months with coaching, homework and DOT...

  14. Mekanisk kredsløbsstøtte ved hjælp af cirkulationspumpe anlagt gennem vena subclavia hos en patient med akut hjertesvigt

    DEFF Research Database (Denmark)

    Hansen, Lars Nikolaj; Fabrin, Anja; Jensen, Marianne Kjær

    2014-01-01

    A 65-year-old female patient suffered biventricular failure due to severe lymphoid myocarditis. Mechanical circulatory support was established with peripheral arterial-venous extracorporeal membrane oxygenation (AV-ECMO). The left ventricle was relieved by subclavian Impella 5.0. AV-ECMO was wean...

  15. Med Kingo på dybt vand

    DEFF Research Database (Denmark)

    Arndal, Lars Stubbe

    2014-01-01

    Tag med digteren Thomas Kingo ud på dybt vand i selskab med lektor og mag.art. Lars Arndal, der kaster nye perspektiver på Kingos forlisdigt Hierte-Suk. Arndal kommer hermed også med et bud på, hvordan man som lærer kan invitere eleverne med på opdagelse i digtet...

  16. Fang CO2 med Aminosyrer

    DEFF Research Database (Denmark)

    Lerche, Benedicte Mai

    2010-01-01

    Med såkaldte “carbon capture-teknikker” er det muligt at rense røgen fra kulfyrede kraftværker, således at den er næsten helt fri for drivhusgassen CO2. Kunsten er at gøre processen tilstrækkeligt billig. Et lovende fangstredskab i denne proces er aminosyrer.......Med såkaldte “carbon capture-teknikker” er det muligt at rense røgen fra kulfyrede kraftværker, således at den er næsten helt fri for drivhusgassen CO2. Kunsten er at gøre processen tilstrækkeligt billig. Et lovende fangstredskab i denne proces er aminosyrer....

  17. Pædagogers samarbejde med lærerne

    DEFF Research Database (Denmark)

    Gulløv, Cristina Daniela

    2017-01-01

    på spil, og de prøver at finde ud af, hvordan de kan være loyale over for deres faglighed. For det andet rejses der et spørgsmål om hvordan pædagoger agerer inklusionsagenter i skolen, samt hvordan dette arbejde formes af eksisterende praksisideologier blandt lærere og pædagoger. I denne sammenhæng...

  18. Samhørighed, interaktion og vidensdeling blandt studerende - Erfaringer fra et ikt-pædagogisk udviklingsprojekt

    DEFF Research Database (Denmark)

    Davidsen, Jacob; Ryberg, Thomas

    2016-01-01

    af Facebook og Moodle, som skulle give de studerende oplevelser og erfaringer med, hvordan de kan bruge og finde inspiration i hinandens arbejde ved at deltage i et online fællesskab sammen med underviserne. Projektet viser, at underviserne spiller en central rolle i udviklingen af online...... at studerende i vid udstrækning anvender sociale netværkssteder, såsom Facebook, i forbindelse med deres studieliv til faglige, men i særdeleshed sociale aktiviteter. Det betyder, at vi som undervisere har et begrænset indblik i, hvad de studerende kommunikerer om og har af problemstillinger i deres studieliv......, hvilket er problematisk i forhold til at udvikle et fagligt fællesskab og forankringspunkt. Det skyldes endvidere, at brugen af det institutionelle system Moodle er begrænset til envejskommunikation fra underviser til studerende. Formålet med udviklingsprojektet var således at skabe et tredje rum imellem...

  19. Prevalence of sexual desire and satisfaction among patients with screen-detected diabetes and impact of intensive multifactorial treatment

    DEFF Research Database (Denmark)

    Pedersen, Mette Bjerggaard; Giraldi, Annamaria; Kristensen, Ellids

    2015-01-01

    Seksuallivet er vigtigt for vores livskvalitet. Blandt mænd og kvinder, der har haft type 2 diabetes i lang tid, er seksuelle problemer hyppige. I ADDITION-studiet om tidlig opsporing og intensiv behandling af type 2-diabetes i almen praksis blev patienterne stillet forskellige spørgsmål om deres...... seksualitet ved 5-års opfølgningsundersøgelsen. Disse spørgsmål dannede baggrund for vores undersøgelse, som viser, at seksuelle problemer også er hyppige blandt mænd og kvinder med diabetes opdaget tidligt i deres sygdomsforløb. Omkring halvdelen af kvinderne og en fjerdedel af mændene i studiet oplevede...

  20. Musikalsk leg med formgivning, timing og vitalitetsformer

    DEFF Research Database (Denmark)

    Holck, Ulla

    2015-01-01

    Ifølge de Udviklingsorienterede Social-Pragmatiske Interventionsformer til børn med Autisme Spektrum Forstyrrelse er en legende indfaldsvinkel, hvor man følger barnets lead, den mest effektive til at engagere yngre børn med autisme eller børn med svær autisme i et gensidigt samspil. Artiklen...

  1. Langtidsforsøg med totrinsforgasseren "Viking"

    DEFF Research Database (Denmark)

    Henriksen, Ulrik Birk; Ahrenfeldt, Jesper; Bentzen, Jens Dall

    Projektets formål har været at få erfaringer med langtidsdrift, samt at løbende forbedre anlæggets komponenter i takt med de indvundne driftserfaringer. Status for Vikingforgasseren ved projektets afslutning er: • En række komponenter er løbende forbedret med henblik på driftssikkerhed, levetid, ...

  2. Lærere arbejder med landskabsdannelse

    DEFF Research Database (Denmark)

    2012-01-01

    Valg af materiale/medie/form: YOUtube videoklip. Valg af arbejdsform: Lærere der er igang med at afprøve praktisk undersøgende arbejde med danske landskabsformer. Begrundelse for valg af materiale/medie/form/arbejdsform: Ultrakort videoklip valgt så 1) lærerne kan dele med kolleger, 2) øvrige...

  3. Kendskab til humant papillomvirus-relateret sygdom blandt kvinder i almen praksis

    DEFF Research Database (Denmark)

    Petersen, Lone Kjeld; Vaesel, Hanne; Brønsgaard, Poul Hede

    2009-01-01

    75% of the adult population has or will become infected by one or more HPV serotypes. The purpose of the study was to investigate the level of knowledge of the cause of cervical cancer, cervical dysplasia and condylomas among women seen in Danish general practice, and to investigate the women......-39 years were included in the study. Only 1.2% of the women correctly stated HPV as the cause of cervical cancer and 0.7% stated HPV as the cause of condylomas. In all, 96.2% thought that general practitioners should actively inform their patients of prophylactic initiatives such as vaccination against...... cervical cancer. Among all women, 96.4% considered HPV-vaccination. CONCLUSION: In this population, knowledge about the cause of cervical cancer and condylomas was limited. There was a clear wish - and expectation - to be actively informed on prophylactic initiatives by the general practitioner...

  4. Diagnostisk udfordring hos patienter med infiltrerende tarmendometriose

    DEFF Research Database (Denmark)

    Sloth, Sigurd Beier; Seyer-Hansen, Mikkel

    2014-01-01

    A considerable proportion of women with endometriosis have intestinal involvement of the endometriosis. Intestinal endometriosis (IE) often results in abdominal pain and thus mimics the symptoms of other bowel diseases, including colon cancer. As a consequence, some women with IE are initially...

  5. Mundhulens mikroflora hos patienter med marginal parodontitis

    DEFF Research Database (Denmark)

    Larsen, Tove; Fiehn, Nils-Erik

    2011-01-01

    ikke dyrkes. Viden om samspillet mellem bakterierne i plakken, som er en biofilm, er ligeledes under hastig udvikling. Dette betyder, at vi i de kommende år løbende må revidere vores forståelse af marginal parodontitis’ mikrobiologi. I nærværende oversigtsartikel præsenteres den eksisterende viden...

  6. Mundhulens mikroflora hos patienter med marginal parodontitis

    DEFF Research Database (Denmark)

    Larsen, Tove; Fiehn, Nils-Erik

    2011-01-01

    Viden om marginal parodontitis’ mikrobiologi tog for alvor fart for ca. 40 år siden. Den tidlige viden var baseret på mikroskopiske og dyrkningsmæssige undersøgelser af den subgingivale plak. Anvendelsen af de nyere molekylærbiologiske metoder har betydet, at vor viden om de ætiologiske faktorer ...

  7. Tur-samspil i musikterapi med børn med svære kommunikationsvanskeligheder

    DEFF Research Database (Denmark)

    Holck, Ulla

    2006-01-01

    præcisering af de træk ved barnets deltagelse i tur-samspillet, som kan indgå i musikterapeutisk assessment af samspil med kommunikationssvage børn. Klinisk tager artiklen udgangspunkt i musikterapeutisk samspil med børn med betydelige funktionsnedsættelser, herunder børn med autisme. Artiklens indhold...

  8. Behandling af hydatidose med albendazol

    DEFF Research Database (Denmark)

    Magnussen, P; Gelletlie, R; Bygbjerg, Ib Christian

    1989-01-01

    Eight patients with hydatidosis treated with albendazol in daily doses of 10 mg/kg daily in courses of 28 days (4-6 courses) were analysed. The patients came from Morocco, Spain, Turkey and Yugoslavia. Seven patients had a cyst (or cysts) in the liver and one had also cysts in the kidneys. One...

  9. Organisk demens blandt tandteknikere

    DEFF Research Database (Denmark)

    Prescott, E; Steendahl, Ulla; Damsgaard, M T

    1989-01-01

    The preparation methylmethacrylate (MMA) an organic solvent which is employed inter alii in the production of prostheses, is regarded as neurotoxic. With the object of illustrating to what extent dental technicians have symptoms compatible with organic dementia as compared with a control group, a...... after very slight exposure. Revision of the occupational environment of dental technicians, including the current hygienic limits for MMA, is recommended.......The preparation methylmethacrylate (MMA) an organic solvent which is employed inter alii in the production of prostheses, is regarded as neurotoxic. With the object of illustrating to what extent dental technicians have symptoms compatible with organic dementia as compared with a control group......, a cross-sectional questionnaire investigation was undertaken in a population consisting of 256 dental technicians and 160 opticians, all of whom were professionally active. The percentage replies for the two group were 88 and 85 respectively. The two groups do not differ from one another as regards...

  10. Organisk demens blandt tandteknikere

    DEFF Research Database (Denmark)

    Prescott, E; Steendahl, Ulla; Damsgaard, M T

    1989-01-01

    The preparation methylmethacrylate (MMA) an organic solvent which is employed inter alii in the production of prostheses, is regarded as neurotoxic. With the object of illustrating to what extent dental technicians have symptoms compatible with organic dementia as compared with a control group...... of information and selection bias are discussed and it is concluded that this investigation confirms the hypothesis that symptoms compatible with organic dementia are commoner among dental technicians. The results raise the suspicion that MMA may cause acute and chronic damage to the central nervous system, even...... after very slight exposure. Revision of the occupational environment of dental technicians, including the current hygienic limits for MMA, is recommended....

  11. Pengespil blandt unge

    DEFF Research Database (Denmark)

    Nielsen, Connie; Heidemann, Julie

    -screeningsinstrument. SFI har tidligere på vegne af Spillemyndigheden under Skatteministeriet (Skat) undersøgt spillemønstret og omfanget af spilleproblemer for voksne i alderen 18-74 år. Til denne undersøgelse har SFI-Survey interviewet 3.814 unge i alderen 12 til 17 år pr. telefon i juli/august 2007. De unge blev...

  12. Bedømmelse af undervisningskompetencer på baggrund af undervisningsportfolio i forbindelse med stillingsansøgninger

    DEFF Research Database (Denmark)

    Kobayashi, Sofie; Christiansen, Frederik V; Rump, Camilla Østerberg

    Formålet er at diskutere undervisningsportfolio og relevante bedømmelseskriterier, for at udveksle erfaringer blandt universiteter og øge kendskab til variation i krav og problematikker ifm bedømmelse....

  13. Politiske diskussioner med familie og venner

    DEFF Research Database (Denmark)

    Levinsen, Klaus; Yndigegn, Carsten

    2016-01-01

    Unge mennesker diskuterer gerne politik med familie og venner, men de er tilbøjelige til at undgå at diskutere politik med personer, der har andre holdninger end dem selv – både når det drejer sig om deres familiemedlemmer, venner og kærester.......Unge mennesker diskuterer gerne politik med familie og venner, men de er tilbøjelige til at undgå at diskutere politik med personer, der har andre holdninger end dem selv – både når det drejer sig om deres familiemedlemmer, venner og kærester....

  14. Hva er det med Irma?

    Directory of Open Access Journals (Sweden)

    Anne Beate Reinertsen

    2016-10-01

    Full Text Available Abstract: This article is about formative quality assessment in a posthuman or newmaterial perspective; embodied knowledges.  Theory and method are written together in immanence to envision complexity.  The aim and scope of the article is to follow the flow of events Irma produces opening up for affirmative poetical critique praxis. Quality is forwarded as an intensity and force in a moment only.  The moment is therefore the only structure of the text, as moving quality. The intention and inner logic of the text is therefore designed to work against fixed definitions and conceptualizations of what quality and quality assessment is.  This way I hope to show what posthuman and newmaterial approaches can contribute with to build cultures of innovation in which quality is assessed and produces again and again. They put differences to work and open up for creating moments of educational justice. Sammendrag: Artikkelen handler om kvalitetsvurdering i et nymaterielt perspektiv: Kroppslig kunnskap og viten. Teori og metode skrives sammen i immanent samtidighet for å gi et bilde på kompleksitet. Både hensikt og mål med artikkelen er å følge den flyten som Irma som hendelse eller event produserer, for å åpne opp potensialitet for en bekreftende eller affirmativ poetiserende kritikkpraksis og en ny forståelse av- og vurdering for kvalitet. Kvalitet skrives fram som en hendelse, intensitet eller kraft i et øyeblikk. Øyeblikket er derfor tekstens eneste og bærende struktur, som kvalitet i bevegelse. Tekstens indre logikk har slik til hensikt å motvirke forsøk på å skape definerte, faste eller bestemte oppfatninger av hva kvalitet er og hvordan kvalitet kan vurderes. På denne måten håper jeg å vise hva nymaterielle perspektiver kan gjøre for å bygge kulturer for innovasjon hvor kvalitet vurderes og produseres igjen og igjen. De setter forskjellighet i bevegelse og åpner opp for å skape rettferdige utdanningsøyeblikk.

  15. Multiple Epiphyseal Dysplasia (MED: A Rare Type of Skeletal Dysplasia

    Directory of Open Access Journals (Sweden)

    Mohammad Imnul Islam

    2012-06-01

    Full Text Available Multiple epiphyseal dysplasia (MED is a congenital disorder of skeletal development that primarily affects the ends of long bones, causing progressive joint and bone inflammation and short stature. Mutations in several genes are responsible for pathogenesis of this disease. We are reporting a case of MED who presented with the complaints of multiple swelling of the joints which was associated with pain during movement for last seven years. The patient had flexion deformity of all the affected joints along with restriction of movement. These were associated with kyphosis, pectus carnitum, knock-knee and short stature. Radiological findings were suggestive of MED. Counseling was done with the parents regarding the etiology, progression and outcome of the disease.DOI: http://dx.doi.org/10.3329/bsmmuj.v5i1.11025 BSMMU J 2012; 5(1:57-60 

  16. Specifik mutation med nålestiksoperation

    DEFF Research Database (Denmark)

    Holme, Inger; Wendt, Toni; Brinch-Pedersen, Henrik

    2014-01-01

    Mutanter af byg er vigtige i forskningen og benyttes også, når der forædles nye sorter til dyrkning. Hidtil har det kun været muligt at inducere mutationer tilfældige steder i genomet. Med helt ny teknologi benyttes proteiner med betegnelsen TALENs til at inducere mutationer i helt specifikke...

  17. Automation med pneumatiske servodrev - status og fremtid

    DEFF Research Database (Denmark)

    Sørensen, Paul Haase

    1996-01-01

    Der er råd for problemer med ulineariteter. Med de nyeste metoder kan der lineære driftsområde udvides. Men pneumatikkomponenter skal være af høj kvalitet, når positionering skal være nøjagtig....

  18. Samhørighed, interaktion og vidensdeling blandt studerende - erfaringer fra et IKT-pædagogisk udviklingsprojekt

    Directory of Open Access Journals (Sweden)

    Jacob Davidsen

    2016-10-01

    Full Text Available I artiklen beskriver vi erfaringer fra et projekt på Aalborg Universitet (AAU, hvor forfatterne designede et forløb med Google+ communities for at skabe øget samhørighed, interaktion og vidensdeling mellem studerende på 1. semester på studiet Kommunikation og Digitale Medier (KDM. Studier viser, at studerende i vid udstrækning anvender sociale netværkssteder, såsom Facebook, i forbindelse med deres studieliv til faglige, men i særdeleshed sociale aktiviteter. Det betyder, at vi som undervisere har et begrænset indblik i, hvad de studerende kommunikerer om og har af problemstillinger i deres studieliv, hvilket er problematisk i forhold til at udvikle et fagligt fællesskab og forankringspunkt. Det skyldes endvidere, at brugen af det institutionelle system Moodle er begrænset til envejskommunikation fra underviser til studerende. Formålet med udviklingsprojektet var således at skabe et tredje rum imellem Facebook og Moodle, som skulle give de studerende oplevelser og erfaringer med, hvordan de kan bruge og finde inspiration i hinandens arbejde ved at deltage i et online-fællesskab sammen med underviserne. Projektet viser, at underviserne spiller en central rolle i udviklingen af online-fællesskabet, men samtidig, at nogle af forløbets aktiviteter har haft positiv indflydelse på de studerendes samhørighed, interaktion og vidensdeling gennem forløbet. In this paper, we share experiences from a project at Aalborg University (AAU, in which the authors designed a course using Google + Communities for the first semester of the Communication and Digital Media programme. In this programme Google + Communities was used to nurture both an academic and social community among the students, through encouraging interaction and knowledge sharing. Studies show that students prefer to use Facebook for academic and social purposes. As a consequence, teachers have minimal insight into the challenges facing students, which is problematic when

  19. Musikterapi med børn med fysiske og psykiske funktionsnedsættelser

    DEFF Research Database (Denmark)

    Holck, Ulla

    2014-01-01

    Indledning: I Danmark er der en lang tradition for musikterapeutisk arbejde med børn med fysiske og psykiske funktionsnedsættelser, og herunder børn med autismespektrumforstyrrelser. De ældste casebeskrivelser stammer fra 1940’erne, og op gennem 50’erne, 60’erne og 70’erne kombinerede pionerermed...

  20. Evaluering af ordning med psykologbehandling af personer med let til moderat depression

    DEFF Research Database (Denmark)

    Fjeldsted, Rita; Christensen, Kaj Sparle

    tidligere evaluering af forsøgsordning af psykologbehandling af depression i perioden 2005-06. 18.419 personer i alderen 18-37 år blev henvist til psykolog i den undersøgte ordning i perioden 1.2.2009 – 31.1.2010, svarende til en henvisningshyppighed på 1,6 % af baggrundsbefolkningen i samme aldersgruppe...... samme niveau som fandtes i evalueringen fra 2007. Remissionsraten for personer med depression ved behandlingsstart er 87 % målt med MDI. Patienters selvrapporterede effekt er 95 %. I opfølgningsgruppen har 89 % ingen depression 3 år efter afsluttet behandling, 56 % har oplevet mindst én ny...... for begge køn, og der ses et fald på 40 % for kvinder og 70 % for mænd over de givne 3 år. Tidsperspektivet er for denne gruppe mere relevant for overordnet vurdering, men der savnes en sammenligningsgruppe. Ifølge spørgeskemadata øges andelen af personer, der er i arbejde, selvforsørgelse eller på SU fra...

  1. Death, dying and informatics: misrepresenting religion on MedLine.

    Science.gov (United States)

    Rodríguez Del Pozo, Pablo; Fins, Joseph J

    2005-07-01

    The globalization of medical science carries for doctors worldwide a correlative duty to deepen their understanding of patients' cultural contexts and religious backgrounds, in order to satisfy each as a unique individual. To become better informed, practitioners may turn to MedLine, but it is unclear whether the information found there is an accurate representation of culture and religion. To test MedLine's representation of this field, we chose the topic of death and dying in the three major monotheistic religions. We searched MedLine using PubMed in order to retrieve and thematically analyze full-length scholarly journal papers or case reports dealing with religious traditions and end-of-life care. Our search consisted of a string of words that included the most common denominations of the three religions, the standard heading terms used by the National Reference Center for Bioethics Literature (NRCBL), and the Medical Subject Headings (MeSH) used by the National Library of Medicine. Eligible articles were limited to English-language papers with an abstract. We found that while a bibliographic search in MedLine on this topic produced instant results and some valuable literature, the aggregate reflected a selection bias. American writers were over-represented given the global prevalence of these religious traditions. Denominationally affiliated authors predominated in representing the Christian traditions. The Islamic tradition was under-represented. MedLine's capability to identify the most current, reliable and accurate information about purely scientific topics should not be assumed to be the same case when considering the interface of religion, culture and end-of-life care.

  2. Death, dying and informatics: misrepresenting religion on MedLine

    Directory of Open Access Journals (Sweden)

    Fins Joseph J

    2005-07-01

    Full Text Available Abstract Background The globalization of medical science carries for doctors worldwide a correlative duty to deepen their understanding of patients' cultural contexts and religious backgrounds, in order to satisfy each as a unique individual. To become better informed, practitioners may turn to MedLine, but it is unclear whether the information found there is an accurate representation of culture and religion. To test MedLine's representation of this field, we chose the topic of death and dying in the three major monotheistic religions. Methods We searched MedLine using PubMed in order to retrieve and thematically analyze full-length scholarly journal papers or case reports dealing with religious traditions and end-of-life care. Our search consisted of a string of words that included the most common denominations of the three religions, the standard heading terms used by the National Reference Center for Bioethics Literature (NRCBL, and the Medical Subject Headings (MeSH used by the National Library of Medicine. Eligible articles were limited to English-language papers with an abstract. Results We found that while a bibliographic search in MedLine on this topic produced instant results and some valuable literature, the aggregate reflected a selection bias. American writers were over-represented given the global prevalence of these religious traditions. Denominationally affiliated authors predominated in representing the Christian traditions. The Islamic tradition was under-represented. Conclusion MedLine's capability to identify the most current, reliable and accurate information about purely scientific topics should not be assumed to be the same case when considering the interface of religion, culture and end-of-life care.

  3. Pneumocystepneumoni ved behandling med infliximab

    DEFF Research Database (Denmark)

    Josephson, Maria Eklund; Kristensen, Lena Hagelskjaer; Andersen, Vibeke

    2008-01-01

    The treatment of ulcerative colitis has improved since the appearance of Tumor Necrosis Factor (TNF)-alpha inhibitors. However, the use of TNF-alpha inhibitors increases the risk of opportunistic infections. We describe two cases of Pneumocystis jiroveci pneumonia during infliximab therapy...... for active ulcerative colitis. They were successfully treated with sulfametoxazole/trimetroprim. High awareness of P. jiroveci pneumonia in patients who develop pulmonary symptoms with hypoxia during TNF-alpha modulator therapy is recommended....

  4. Kardiovaskulaer regeneration med mesenkymale stamceller

    DEFF Research Database (Denmark)

    Mathiasen, Anders Bruun; Sørensen, Mandana Haack; Jørgensen, Erik

    2010-01-01

    a multipotent differentiation capacity. Clinical MSC studies on patients with ischaemic heart disease have shown improved left ventricular function and perfusion and also a reduction in infarct size and symptoms. In this short review we provide a status on MSC regenerative treatment in cardiovascular disease.......Treatment with stem cells with a regenerative potential is a new form of therapy that is being studied intensively. Mesenchymal stem cells or stromal cells (MSC) are a promising source of stem cells for regenerative therapy. MSC are easy to isolate and culture, expand in vitro and have...

  5. Radiografi med patienten i centrum?

    DEFF Research Database (Denmark)

    Møller, Louise

    2016-01-01

    This dissertations aim is to look, how radiography is performed so the patient is in center in radiological examinations, as the Danish definition of radiography prescribes. The method used in the project is an ANT analysis of actors present and of how radiography is performed in practice, combined...... whit an analysis based on Foucault’s theory of power, to answer why the examinations are build of these particular actions. This project argues that there is no center in radiography in the simple sense but instead several centers are present formed by actions and all actors must contribute...

  6. Kardiovaskulaer regeneration med mesenkymale stamceller

    DEFF Research Database (Denmark)

    Mathiasen, Anders Bruun; Sørensen, Mandana Haack; Jørgensen, Erik

    2010-01-01

    Treatment with stem cells with a regenerative potential is a new form of therapy that is being studied intensively. Mesenchymal stem cells or stromal cells (MSC) are a promising source of stem cells for regenerative therapy. MSC are easy to isolate and culture, expand in vitro and have...... a multipotent differentiation capacity. Clinical MSC studies on patients with ischaemic heart disease have shown improved left ventricular function and perfusion and also a reduction in infarct size and symptoms. In this short review we provide a status on MSC regenerative treatment in cardiovascular disease....

  7. Bliv klogere på Mycoplasma bovis - Beslægtethed blandt de danske stammer: Afsløret

    DEFF Research Database (Denmark)

    Kokotovic, Branko

    .bovis) som oftest findes i forbindelse med mastitis, lunge- og ledbetændelse. Tidligere undersøgelser har rapporteret M. bovis forbundet med op til 52 % af mastitis tilfælde (1) og op til 36 % af kalvedødeligheden på grund af luftvejsinfektioner (2, 3). Der findes ikke præcise, nyere beregninger over...... konsekvenser af M. bovis relateret sygdomme, men det anses, at infektionen hvert år globalt set pålægger en økonomisk byrde til kvægbruget i en multimillion skala (3). M. bovis blev for første gang påvist i Danmark i 1981 og gennem 1980’erne har bakterien forårsaget store udbrud af mastitis (4, 5). I de...... følgende årtier blev bakterien isoleret sporadisk fra mange forskellige kvægbesætninger, men på trods en tilsyneladende stigende forekomst i 1990’erne (6), blev der ikke registret omfattende sundhedsmæssige problemer som følge af M. bovis smitte. Siden 2011 er M. bovis dog kommet i fokus igen på grund af...

  8. Personer med fysiske handicap og psykiske lidelser

    DEFF Research Database (Denmark)

    Larsen, Malene Rode; Larsen, Mona

    2018-01-01

    Det er velkendt, at personer med fysiske handicap i større omfang er i beskæftigelse end personer med psykiske lidelser. Formålet med dette notat er at forøge den eksisterende viden om, hvorfor der er forskel på de to gruppers beskæftigelsesomfang. Vi undersøger, om forskelle mellem de to grupper......, hvad angår en række målbare personkarakteristika og deres sammenhæng med gruppernes beskæftigelsessandsynlighed, spiller en rolle i denne forbindelse. De undersøgte personkarakteristika er: a) personforhold som fx alder, etnisk oprindelse, uddannelse og sværhedsgrad af handicap, b) personlighedstræk...

  9. Fysisk rehabilitering i forbindelse med behandling af hæmatologiske sygdomme

    DEFF Research Database (Denmark)

    Høgdal, Nina; Bartels, Frederik Reith; Smith, Nicholas Simon

    2015-01-01

    I denne statusartikel vurderes det, hvorvidt det eksisterende fysioterapeutiske træningstilbud under behandling af maligne sygdomme med højdosis kemoterapi og perifer stamcellestøtte (HD-ASCT) lever op til anbefalingerne i Kræftplan III. Alle seks hospitaler i Danmark, som behandler patienter med...

  10. Food-Dependent Exercise-Induced Anaphylaxis - Kasuistik med hydrolyseret valleprotein

    DEFF Research Database (Denmark)

    Junker Christensen, Morten

    2013-01-01

    Formål / Introduktion: Patienter med Food-Dependent Exercise-Induced Anaphylaxis (FDEIA) eller løbershock kan udvikle livstruende allergiske reaktioner (anafylaksi), når de kombinere fysisk anstrengelse med samtidig indtagelse af et normalt tolereret fødeemne - oftest hvede. Hydrolysering af prot...

  11. Adoption, psykiske lidelser og kriminalitet blandt 15-27 årige. En landsomfattende sammenlignelig registerbaseret undersøgelse af adopterede og af stedbørn sammenlignet med ikke-adopterede i Danmark

    DEFF Research Database (Denmark)

    Laubjerg, Merete; Petersson, Birgit

    2010-01-01

    adopterede > 12 mdr. samt stedbørn har 3-4 gange højere risiko. Derimod er 'oprindelse' en risikofaktor for kriminalitet for internationalt adopterede og for indvandrere. Alder ved adoption, kontakt til psykiatrien og 'bor ikke hos forælder' er risiko for dom og recidiv. Drenge får i langt højere grad end...

  12. Effektelektronik - teknologi med energibesparelser og forbedret performance

    DEFF Research Database (Denmark)

    Blaabjerg, Frede

    2004-01-01

    Lige siden transistoren blev opfundet, har det altid været ønskeligt at kunne anvende en sådan til at styre store strømme/spændinger i elektriske systemer. Det er teknologisk også sket, først med tyristorer til styring af store effekter, men siden hen også med den bipolare transistor MOSFET, samt...

  13. Ud med Freud, Marx og Lacan

    DEFF Research Database (Denmark)

    Clasen, Mathias

    2009-01-01

    Det er på høje tid, at humanister løsriver sig fra deres forældede teorier. Freud, Marx og Lacan skal erstattes med evolutionspsykologi, biologi og kognitionsvidenskab.......Det er på høje tid, at humanister løsriver sig fra deres forældede teorier. Freud, Marx og Lacan skal erstattes med evolutionspsykologi, biologi og kognitionsvidenskab....

  14. Ukraine i fokus sammen med Georgien

    DEFF Research Database (Denmark)

    Fledelius, Karsten

    2017-01-01

    Der er god grund til at sammenligne Ukraine og Georgien, nu fokuslande for Danmark, og der er god grund til at støtte disse to eks-sovjetiske stater med i høj grad parallelle problemer.......Der er god grund til at sammenligne Ukraine og Georgien, nu fokuslande for Danmark, og der er god grund til at støtte disse to eks-sovjetiske stater med i høj grad parallelle problemer....

  15. Sociale indsatser til mennesker med ADHD

    DEFF Research Database (Denmark)

    Bengtsson, Steen; Alim, Winnie; Holmskov, Henriette

    Igennem de seneste år har flere og flere fået stillet diagnosen ADHD, som er en adfærdsmæssig forstyrrelse. Mennesker med ADHD har meget forskelligt støttebehov, og rapportens formål er at skabe overblik over de eksisterende sociale indsatser og tilbud til børn, unge og voksne med ADHD. Langt de...... ansvar for sociale end for terapeutiske tilbud i forhold til gruppen med ADHD. Mange voksne med ADHD beskriver, at det kræver mange ressourcer at få den fornødne støtte fra kommunen, mens forældre til børn med ADHD oplever det som nemmere at få adgang til de rette støttetilbud. Men begge grupper møder...... mange udfordringer som fx manglende koordinering og hyppige sagsbehandlerskift. Rapporten er udarbejdet i tilknytning til Servicestyrelsens projekt ’Ny og forstærket indsats til børn, unge og voksne med ADHD’ og er finansieret af Socialministeriet....

  16. MED13L-related intellectual disability: involvement of missense variants and delineation of the phenotype.

    Science.gov (United States)

    Smol, T; Petit, F; Piton, A; Keren, B; Sanlaville, D; Afenjar, A; Baker, S; Bedoukian, E C; Bhoj, E J; Bonneau, D; Boudry-Labis, E; Bouquillon, S; Boute-Benejean, O; Caumes, R; Chatron, N; Colson, C; Coubes, C; Coutton, C; Devillard, F; Dieux-Coeslier, A; Doco-Fenzy, M; Ewans, L J; Faivre, L; Fassi, E; Field, M; Fournier, C; Francannet, C; Genevieve, D; Giurgea, I; Goldenberg, A; Green, A K; Guerrot, A M; Heron, D; Isidor, B; Keena, B A; Krock, B L; Kuentz, P; Lapi, E; Le Meur, N; Lesca, G; Li, D; Marey, I; Mignot, C; Nava, C; Nesbitt, A; Nicolas, G; Roche-Lestienne, C; Roscioli, T; Satre, V; Santani, A; Stefanova, M; Steinwall Larsen, S; Saugier-Veber, P; Picker-Minh, S; Thuillier, C; Verloes, A; Vieville, G; Wenzel, M; Willems, M; Whalen, S; Zarate, Y A; Ziegler, A; Manouvrier-Hanu, S; Kalscheuer, V M; Gerard, B; Ghoumid, Jamal

    2018-03-06

    Molecular anomalies in MED13L, leading to haploinsufficiency, have been reported in patients with moderate to severe intellectual disability (ID) and distinct facial features, with or without congenital heart defects. Phenotype of the patients was referred to "MED13L haploinsufficiency syndrome." Missense variants in MED13L were already previously described to cause the MED13L-related syndrome, but only in a limited number of patients. Here we report 36 patients with MED13L molecular anomaly, recruited through an international collaboration between centers of expertise for developmental anomalies. All patients presented with intellectual disability and severe language impairment. Hypotonia, ataxia, and recognizable facial gestalt were frequent findings, but not congenital heart defects. We identified seven de novo missense variations, in addition to protein-truncating variants and intragenic deletions. Missense variants clustered in two mutation hot-spots, i.e., exons 15-17 and 25-31. We found that patients carrying missense mutations had more frequently epilepsy and showed a more severe phenotype. This study ascertains missense variations in MED13L as a cause for MED13L-related intellectual disability and improves the clinical delineation of the condition.

  17. The MED-SUV Multidisciplinary Interoperability Infrastructure

    Science.gov (United States)

    Mazzetti, Paolo; D'Auria, Luca; Reitano, Danilo; Papeschi, Fabrizio; Roncella, Roberto; Puglisi, Giuseppe; Nativi, Stefano

    2016-04-01

    In accordance with the international Supersite initiative concept, the MED-SUV (MEDiterranean SUpersite Volcanoes) European project (http://med-suv.eu/) aims to enable long-term monitoring experiment in two relevant geologically active regions of Europe prone to natural hazards: Mt. Vesuvio/Campi Flegrei and Mt. Etna. This objective requires the integration of existing components, such as monitoring systems and data bases and novel sensors for the measurements of volcanic parameters. Moreover, MED-SUV is also a direct contribution to the Global Earth Observation System of Systems (GEOSS) as one the volcano Supersites recognized by the Group on Earth Observation (GEO). To achieve its goal, MED-SUV set up an advanced e-infrastructure allowing the discovery of and access to heterogeneous data for multidisciplinary applications, and the integration with external systems like GEOSS. The MED-SUV overall infrastructure is conceived as a three layer architecture with the lower layer (Data level) including the identified relevant data sources, the mid-tier (Supersite level) including components for mediation and harmonization , and the upper tier (Global level) composed of the systems that MED-SUV must serve, such as GEOSS and possibly other global/community systems. The Data level is mostly composed of existing data sources, such as space agencies satellite data archives, the UNAVCO system, the INGV-Rome data service. They share data according to different specifications for metadata, data and service interfaces, and cannot be changed. Thus, the only relevant MED-SUV activity at this level was the creation of a MED-SUV local repository based on Web Accessible Folder (WAF) technology, deployed in the INGV site in Catania, and hosting in-situ data and products collected and generated during the project. The Supersite level is at the core of the MED-SUV architecture, since it must mediate between the disparate data sources in the layer below, and provide a harmonized view to

  18. Social indsats til borgere med erfaring fra salg af sex

    DEFF Research Database (Denmark)

    Mehlsen, Line; Amilon, Anna; Henriksen, Theresa Dyrvig

    2017-01-01

    Formålet med denne guide er at give endnu flere kommuner inspiration og vejledning til, hvordan man kan implementere og arbejde med CTI-forløb over for borgere med prostitutionserfaring. Manglende viden om borgere med prostitutionserfaringer gør det svært for kommunerne at hjælpe borgerne med de ...

  19. Retrieving clinical evidence: a comparison of PubMed and Google Scholar for quick clinical searches.

    Science.gov (United States)

    Shariff, Salimah Z; Bejaimal, Shayna Ad; Sontrop, Jessica M; Iansavichus, Arthur V; Haynes, R Brian; Weir, Matthew A; Garg, Amit X

    2013-08-15

    Physicians frequently search PubMed for information to guide patient care. More recently, Google Scholar has gained popularity as another freely accessible bibliographic database. To compare the performance of searches in PubMed and Google Scholar. We surveyed nephrologists (kidney specialists) and provided each with a unique clinical question derived from 100 renal therapy systematic reviews. Each physician provided the search terms they would type into a bibliographic database to locate evidence to answer the clinical question. We executed each of these searches in PubMed and Google Scholar and compared results for the first 40 records retrieved (equivalent to 2 default search pages in PubMed). We evaluated the recall (proportion of relevant articles found) and precision (ratio of relevant to nonrelevant articles) of the searches performed in PubMed and Google Scholar. Primary studies included in the systematic reviews served as the reference standard for relevant articles. We further documented whether relevant articles were available as free full-texts. Compared with PubMed, the average search in Google Scholar retrieved twice as many relevant articles (PubMed: 11%; Google Scholar: 22%; PGoogle Scholar: 8%; P=.07). Google Scholar provided significantly greater access to free full-text publications (PubMed: 5%; Google Scholar: 14%; PGoogle Scholar returns twice as many relevant articles as PubMed and provides greater access to free full-text articles.

  20. PubMed Medical Publications From Libya

    Directory of Open Access Journals (Sweden)

    Bakoush O

    2007-01-01

    Full Text Available Medical research and publications are the back-bone for advancing the medical field. We identified the PubMed medical publications that are affiliated with Libya to shed some light on the contribution of this country’s medical community to the PubMed database. All publications affiliated with Libya in the PubMed were counted over a five year period ending December 2006. We also used the same method to obtain data on the PubMed medical publications from Tunisia, Morocco and Yemen. Tunisia had the largest number of PubMed publications among the studied countries: 20.4 publications per million population per year and 7.2 publications per year per one billion US$ GDP. Libya had much fewer publications: 2.4 publications per million population per year and 0.4 publications per one billion US$ GDP. The citation frequency for Libyan published research was very low compared to Tunisian and Moroccan related research. Conclusion: This preliminary analysis shows that medical research output in Libya is about twenty times less than in other countries with similar backgrounds, and that it needs to be enhanced.

  1. Ti år med formidlingspligt

    DEFF Research Database (Denmark)

    Meyer, Gitte

    2014-01-01

    Jubilæet blev markeret ved et symposium - men hvor var journalisterne, og hvor var forskerne? For få uger siden lagde TV 2 hus til et symposium om videnskab, formidling, journalistik og spin. Danske Videnskabsjournalister og Akademiet for de Tekniske Videnskaber tog med arrangementet et behjertet...... initiativ. De ville gøre status efter ti år med lovfæstet formidlingspligt på universiteterne. Samtidig lagde de op til et kritisk blik på universitetsverdenens kommunikationsafdelinger...

  2. Forandringslæring med autismediagnoser?

    DEFF Research Database (Denmark)

    Gustafson, Kari Ingrid; Mørck, Line Lerche

    2013-01-01

    Rasmus’ ændringer i læring, selvforståelse og tilhørsforhold perspektiveres med andre ASF-diagnostiseredes læring udforsket bl.a. gennem gruppeinterviews i regi af Asperger-foreningen. Artiklen byder således på et alternativ i form af at forstå forandringslæring som overskridende læring, med langt større...... hvor fx Asperger-foreningen, lærere og skolebørns- og unges-fællesskaber, samt forældrene er vigtige aktører i overskridelsen af marginalisering....

  3. Hvad SKER der med drikkevandet i USA?

    DEFF Research Database (Denmark)

    Ramsay, Loren Mark

    2017-01-01

    Forskellige lande har forskellige traditioner indenfor drikkevandsbehandling. Denne beretning fra ”Water Quality Technology Conference” i USA er set med en særlig vinkel, da forfatteren er amerikansk statsborger, men har arbejdet i den danske vandbranche i mere end 25 år.......Forskellige lande har forskellige traditioner indenfor drikkevandsbehandling. Denne beretning fra ”Water Quality Technology Conference” i USA er set med en særlig vinkel, da forfatteren er amerikansk statsborger, men har arbejdet i den danske vandbranche i mere end 25 år....

  4. MedWatch, the FDA Safety Information and Adverse Event Reporting Program

    Science.gov (United States)

    ... Reporting Program MedWatch: The FDA Safety Information and Adverse Event Reporting Program Share Tweet Linkedin Pin it ... approved information that can help patients avoid serious adverse events. Potential Signals of Serious Risks/New Safety ...

  5. PubMed, Internet Grateful Med, and Ovid: a comparison of three MEDLINE Internet interfaces.

    Science.gov (United States)

    De Groote, S L

    2000-01-01

    Three MEDLINE Internet interfaces are compared: PubMed, Internet Grateful Med, and Ovid MEDLINE. Although these interfaces all search MEDLINE, significant differences exist in terms of their search interfaces, presentation of results, and special features. This paper examines these variations and explores some of the advantages and disadvantages of the three interfaces.

  6. PubMedReco: A Real-Time Recommender System for PubMed Citations.

    Science.gov (United States)

    Samuel, Hamman W; Zaïane, Osmar R

    2017-01-01

    We present a recommender system, PubMedReco, for real-time suggestions of medical articles from PubMed, a database of over 23 million medical citations. PubMedReco can recommend medical article citations while users are conversing in a synchronous communication environment such as a chat room. Normally, users would have to leave their chat interface to open a new web browser window, and formulate an appropriate search query to retrieve relevant results. PubMedReco automatically generates the search query and shows relevant citations within the same integrated user interface. PubMedReco analyzes relevant keywords associated with the conversation and uses them to search for relevant citations using the PubMed E-utilities programming interface. Our contributions include improvements to the user experience for searching PubMed from within health forums and chat rooms, and a machine learning model for identifying relevant keywords. We demonstrate the feasibility of PubMedReco using BMJ's Doc2Doc forum discussions.

  7. DynaMed Plus®: An Evidence-Based Clinical Reference Resource.

    Science.gov (United States)

    Charbonneau, Deborah H; James, LaTeesa N

    2018-01-01

    DynaMed Plus ® from EBSCO Health is an evidence-based tool that health professionals can use to inform clinical care. DynaMed Plus content undergoes a review process, and the evidence is synthesized in detailed topic overviews. A unique three-level rating scale is used to assess the quality of available evidence. Topic overviews summarize current evidence and provide recommendations to support health providers at the point-of-care. Additionally, DynaMed Plus content can be accessed via a desktop computer or mobile platforms. Given this, DynaMed Plus can be a time-saving resource for health providers. Overall, DynaMed Plus provides evidence summaries using an easy-to-read bullet format, and the resource incorporates images, clinical calculators, patient handouts, and practice guidelines in one place.

  8. Global klimaovervågning med GNSS

    DEFF Research Database (Denmark)

    Madsen, Finn Bo; Khan, Shfaqat Abbas; Nielsen, Jens Emil

    2010-01-01

    Hvornår bliver de folkerige floddeltaer i Asien ubeboelige, hvornår forsvinder Maldiverne eller som merhuset på Danmarks Vestkyst. Verdenshavene stiger i takt med at ismasserne ved polerne smelter og ledes ud i oceanerne. Et centralt spørgsmål for hele verdenssamfundet er: hvor hurtigt sker det o...

  9. Historien med stort H endte i '89

    DEFF Research Database (Denmark)

    Østergaard, Uffe

    2015-01-01

    Revolution. Uffe Østergaard, Jean Monnet professor i europæisk historie på Copenhagen Business School, tager os med op, og betragter debatten om årsagerne til, og betydningen af, Murens fald i fugleperspektiv. Hvorfor var der ingen, der havde forudset begivenhederne?...

  10. MedAustron - Austrian Hadron Therapy Centre

    CERN Document Server

    Benedikt, M; 10.1109/NSSMIC.2008.4774090

    2009-01-01

    MedAustron is a synchrotron based accelerator facility for cancer treatment with proton and carbon ion beams. In addition to the clinical application, the accelerator will also provide beams for non-clinical research, in the fields of medical radiation physics, radiation biology and experimental physics.

  11. Kørsel med spiritus og stoffer

    DEFF Research Database (Denmark)

    Bernhoft, Inger Marie; Hels, Tove; Janstrup, Kira

    2012-01-01

    Alkohol er væsentlig hyppigere til stede hos alvorligt tilskadekomne bilister end misbrugs- og lægemiddelstoffer, hvorimod forekomsten hos bilister i trafikken er ligeligt delt mellem alkohol og andre stoffer. Højeste risiko for alvorlige personskadeuheld findes hos bilister, der kører med ulovli...

  12. Musikterapi med børn med svær autisme - en litteraturgennemgang

    Directory of Open Access Journals (Sweden)

    Ulla Holck

    2003-03-01

    Full Text Available Faglitteratur om musikterapi med børn med autisme er omfattende og indeholder såvel kvalitative case-beskrivelser som kvantitative forskningsundersøgelser. I artiklen gennemgås faglitteraturen systematisk med henblik på at specifi cere musikterapiens effekt og virkemåder i forhold til denne målgruppe. Vægten ligger på børn med svær autisme, men litteratur om voksne højtfungerende personer med autisme inddrages også. Forskningslitteraturen viser, at det især er inden for områderne koncentration, visuel opmærksomhed, respons og initiativ, samt brug af stemme og tur-tagning, at musikterapi har en effekt. Case-litteraturen begrunder denne effekt med musikkens evne til at være redundant, anvendelse af imitation og responsfremmende teknikker (overraskelse etc., fælles opbyggede samspilsformer, samt det temporale-interaktive element i improvisatorisk musikterapi. Ud fra en interaktionsteoretisk indfaldsvinkel sammenkobles effekten endvidere med, at den musikalske interaktion hjælper musikterapeuten til at fastholde et dynamisk udtryk, hvilket er afgørende i forhold til en klientgruppe, der ofte giver ´flad´ eller stærkt afvigende feedback.

  13. Udvendig efterisolering af gavle med præfabrikerede komponenter

    DEFF Research Database (Denmark)

    Nørregaard, M.; Stampe, M.; Kjær, A.

    Rapporten bringer resultaterne af et demonstrationsprojekt, hvor en fritliggende gavl på hver af to ældre etageejendomme blev efterisoleret med præfabrikerede komponenter. Den ene gavl blev beklædt med komponenter af fiberbeton monteret fra stillads, den anden med store stålkassetter monteret med...... kran og lift....

  14. Om computerberegnede tommelfingerregler i forbindelse med pensionsopsparing

    DEFF Research Database (Denmark)

    Møller, Michael; Waldstrøm, Stephan

    2013-01-01

    Beslutninger i forbindelse med pension er mange og komplicerede: Hvornår og hvor meget skal spares op, hvordan skal pengene investeres, og hvilke forsikringsydelser skal købes. Obligatoriske pensionsordninger er en ”one size fits all” model, som for mange vil ramme i underkanten af det forventede...... behov. Der er behov for tommelfingerregler, der kan hjælpe alle dem, der på den ene side ikke vil nøjes med deres obligatoriske ordning men på den anden side finder beslutninger om pension of forsikring vanskelige. Modellerne kan aldrig blive perfekte. Det lader sig ikke gøre i en usikker verden. Men de...

  15. Hvad skal vi med Trump-satire?

    DEFF Research Database (Denmark)

    Møller, Mette

    2017-01-01

    Trump-satire er et stort hit, og særligt en lang række satiriske videohilsner til Trump fra lande verden over får folk til at trække på smilebåndet. Men hvorfor er det så sjovt at gøre grin med Trump, og hvad kan vi bruge den politiske humor til?......Trump-satire er et stort hit, og særligt en lang række satiriske videohilsner til Trump fra lande verden over får folk til at trække på smilebåndet. Men hvorfor er det så sjovt at gøre grin med Trump, og hvad kan vi bruge den politiske humor til?...

  16. Analys av nickel med ICP-MS

    OpenAIRE

    Wallman, Karin; Löfgren, Stefan; Sonesten, Lars; Demandt, Christian

    2009-01-01

    Vid en granskning av nickelhalter för perioden 1985-2007 upptäcktes ett nivåskifte i tidsserierna på flera stationer mellan 2001 och 2002. Skiftet visade sig bero på att prover innan 2002 inte korrigerades för kalciuminterferens, medan prover under åren 2002-2007 korrigerades. Syftet med denna rapport är att utreda om resultaten före 2002 i efterhand kan korrigeras för kalciuminterferensen. Från 2002 finns ett antal prover (N=347) med resultat som både är kalciumkorrigerade och som inte är de...

  17. Bøger med QR-lyd

    DEFF Research Database (Denmark)

    Hellensberg, Christina

    2015-01-01

    Anmeldelse af DigiRead engelsk supplerende læsning med QR-lyd. Lyd på QR-koder til bøger kræver smartphone eller tablet; devices, kun nogle elever i indskolingen har adgang til, men som er lige ved hånden for en stor del af mellemtrinnets elever. Men kvaliteten af lyden er god; rigtig god...

  18. Hvordan slipper man af med fantomsmerter?

    DEFF Research Database (Denmark)

    Gad, Ulrik Pram

    2008-01-01

    Finn Lynge ligner i Den vanskelige tango dén post-koloniale tilstand, som Grønland befinder sig i, med de smerter, som Peter Freuchen havde i sit træben. Artiklen undersøger, om nye metaforer og en ny sprogpolitik kan bruges som kur mod Grønlands fantomsmerter. Konklusionen er for det første, at ...

  19. Clinical Investigation Program, RCS MED-300 (RI).

    Science.gov (United States)

    1984-10-01

    was to be the standard of quality for medical botany until well into the medieval period. He accomplished this prodigious task while traveling as a...medical thought until late medieval times. Another little known role of animals in advancing surgery, especially gyne- cologic surgery, in the 16th...Investigation 1. Rothman T:"de Laguna’s commentaries on hallucinogenic drugs and witchcraft in Dioscorides’ materia medica." Bull Hist Med 1972, 46

  20. Inklusion i folkeskolen med musik og musikterapi

    DEFF Research Database (Denmark)

    Lindvang, Charlotte

    2014-01-01

    I denne artikel sættes der fokus på nogle af de problemer og udfordringer som knytter sig til kravet om inklusion af børn med særlige behov i den almindelige folkeskole, og der argumenteres for at styrke anvendelsen af musik i forhold til at skabe fællesskab og optimere børnenes opmærksomhed og...

  1. Sydkorea: Teknologiske tigerspring med globale udfordringer

    DEFF Research Database (Denmark)

    Brynskov, Martin

    2010-01-01

    Sydkorea har gennemgået en utrolig udvikling fra u-land til førende i-land i løbet af få årtier. Helt centralt står den teknologiske eksport af elektronik, biler og skibsbyggeri i verdenseliten. Men på trods af de mange succeser er der også udfordringer. Denne analyse viser – med aktuelle eksempl...

  2. Technical development of PubMed Interact: an improved interface for MEDLINE/PubMed searches

    OpenAIRE

    Muin, Michael; Fontelo, Paul

    2006-01-01

    Abstract Background The project aims to create an alternative search interface for MEDLINE/PubMed that may provide assistance to the novice user and added convenience to the advanced user. An earlier version of the project was the 'Slider Interface for MEDLINE/PubMed searches' (SLIM) which provided JavaScript slider bars to control search parameters. In this new version, recent developments in Web-based technologies were implemented. These changes may prove to be even more valuable in enhanci...

  3. Med sjefen på Facebook: En studie av ledere som er "venner" med sine ansatte

    OpenAIRE

    Jensen, Anita

    2014-01-01

    MR690 Masteroppgave i organisasjon og ledelse - utdanningsledelse Formålet med studien er å belyse hvordan aktiv bruk av sosiale medier, i dette tilfellet Facebook, påvirker relasjoner mellom mennesker. Hva skjer når en tar i bruk en websjanger som i utgangspunktet er umiddelbar og uformell, til jobbrelatert og mer formell kommunikasjon? Er det sjangeren eller relasjonen som endres? Søkelyset rettes mot ledere som er “venner” med sine medarbeidere, og problemstillingen er...

  4. Digital kommunikation med den offentlige sektor

    DEFF Research Database (Denmark)

    Berger, Jesper; Andersen, Kim Normann

    2013-01-01

    til. I denne undersøgelse sættes der fokus på myndighedernes besvarelse af den digitale post. Digital post blev bl.a. etableret som et alternativ til almindelig e-mail for at det offentlige kan kommunikere med borgere og virksomheder på en sikker måde, dvs. uden at uvedkommende kan få adgang til...... følsomme oplysninger. Fokus for undersøgelsen er hvordan håndterer myndighederne besvarelserne i den digitale postkasse: svarer de på digital post og e-mail, hvor hurtigt svarer de og er svarene brugbare? Undersøgelsen medtager myndighedernes besvarelse af digital post og e-mail, dels for at kunne...... sammenligne de to digitale kanaler og for at kunne sammenligne med en tidligere undersøgelse af digital kommunikation med det offentlige. Herudover er der tidligere gennemført en undersøgelse af e-mail svar og svartider i New Zealand og Australien. De danske resultater fra e-mail undersøgelsen, men ikke...

  5. Digital kommunikation med den offentlige sektor

    DEFF Research Database (Denmark)

    Berger, Jesper Bull; Andersen, Kim Normann

    digital postkasse, som borgerne kunne skrive til. I denne undersøgelse sættes der fokus på myndighedernes besvarelse af den digitale post. Digital post blev bl.a. etableret som et alternativ til almindelig e-mail for at det offentlige kan kommunikere med borgere og virksomheder på en sikker måde, dvs....... uden at uvedkommende kan få adgang til følsomme oplysninger. Fokus for undersøgelsen er hvordan håndterer myndighederne besvarelserne i den digitale postkasse: svarer de på digital post og e-mail, hvor hurtigt svarer de og er svarene brugbare? Vi har også undersøgt besvarelse af e-mail, dels...... for at kunne sammenligne de to digitale kanaler og for at kunne sammenligne med en tidligere undersøgelse af digital kommunikation med det offentlige. Herudover er der tidligere gennemført en undersøgelse af e-mail svar og svartider i New Zealand og Australien. De danske resultater fra e-mail undersøgelsen...

  6. Digital kommunikation med den offentlige sektor

    DEFF Research Database (Denmark)

    Berger, Jesper Bull; Andersen, Kim Normann

    til. I denne undersøgelse sættes der fokus på myndighedernes besvarelse af den digitale post. Digital post blev bl.a. etableret som et alternativ til almindelig e-mail for at det offentlige kan kommunikere med borgere og virksomheder på en sikker måde, dvs. uden at uvedkommende kan få adgang til...... følsomme oplysninger. Fokus for undersøgelsen er hvordan håndterer myndighederne besvarelserne i den digitale postkasse: svarer de på digital post og e-mail, hvor hurtigt svarer de og er svarene brugbare? Undersøgelsen medtager myndighedernes besvarelse af digital post og e-mail, dels for at kunne...... sammenligne de to digitale kanaler og for at kunne sammenligne med en tidligere undersøgelse af digital kommunikation med det offentlige. Herudover er der tidligere gennemført en undersøgelse af e-mail svar og svartider i New Zealand og Australien. De danske resultater fra e-mail undersøgelsen, men ikke...

  7. Samtidig iltbehandling ved anstrengelsesudløst hypoksæmi forbedrer den fysiske formåen og reducerer åndenød hos patienter med KOL

    DEFF Research Database (Denmark)

    Kjeldgaard, Peter; Ringbæk, Thomas; Lange, Peter

    2011-01-01

    Many chronic obstructive pulmonary disease patients suffer from dyspnoea and reduced physical abilities. Some of the patients exhibit desaturation during physical exercise. Few studies have examined if oxygen therapy during physical exercise can relieve symptoms and improve outcomes of pulmonary ...

  8. Samtidig iltbehandling ved anstrengelsesudløst hypoksæmi forbedrer den fysiske formåen og reducerer åndenød hos patienter med KOL

    DEFF Research Database (Denmark)

    Kjeldgaard, Peter; Ringbæk, Thomas; Lange, Peter

    2011-01-01

    Many chronic obstructive pulmonary disease patients suffer from dyspnoea and reduced physical abilities. Some of the patients exhibit desaturation during physical exercise. Few studies have examined if oxygen therapy during physical exercise can relieve symptoms and improve outcomes of pulmonary...

  9. Fortsat tuberkuloseproblemer blandt danskere og grønlændere i Danmark og behov for styrket kontrol

    DEFF Research Database (Denmark)

    Lillebæk, Troels; Andersen, Ase Bengård; Seersholm, Niels Jørgen

    2012-01-01

    Active transmission of Mycobacterium tuberculosis (Mt) continues at surprisingly high rates in Denmark. The transmission is particularly observed in specific high risk segments of the population with social problems such as homelessness, alcohol, and/or drug abuse. The patients are infected...

  10. Fortsat tuberkuloseproblemer blandt danskere og grønlændere i Danmark og behov for styrket kontrol

    DEFF Research Database (Denmark)

    Lillebæk, Troels; Andersen, Ase Bengård; Seersholm, Niels Jørgen

    2012-01-01

    Active transmission of Mycobacterium tuberculosis (Mt) continues at surprisingly high rates in Denmark. The transmission is particularly observed in specific high risk segments of the population with social problems such as homelessness, alcohol, and/or drug abuse. The patients are infected...... with the "Danish Cluster 2" Mt outbreak strain, and the transmission is attributed to delayed diagnosis. This situation demands increased focus on early tuberculosis diagnosis, control of transmission, and improved actions calls for prioritising the prevention and control of tuberculosis politically...

  11. Technical development of PubMed interact: an improved interface for MEDLINE/PubMed searches.

    Science.gov (United States)

    Muin, Michael; Fontelo, Paul

    2006-11-03

    The project aims to create an alternative search interface for MEDLINE/PubMed that may provide assistance to the novice user and added convenience to the advanced user. An earlier version of the project was the 'Slider Interface for MEDLINE/PubMed searches' (SLIM) which provided JavaScript slider bars to control search parameters. In this new version, recent developments in Web-based technologies were implemented. These changes may prove to be even more valuable in enhancing user interactivity through client-side manipulation and management of results. PubMed Interact is a Web-based MEDLINE/PubMed search application built with HTML, JavaScript and PHP. It is implemented on a Windows Server 2003 with Apache 2.0.52, PHP 4.4.1 and MySQL 4.1.18. PHP scripts provide the backend engine that connects with E-Utilities and parses XML files. JavaScript manages client-side functionalities and converts Web pages into interactive platforms using dynamic HTML (DHTML), Document Object Model (DOM) tree manipulation and Ajax methods. With PubMed Interact, users can limit searches with JavaScript slider bars, preview result counts, delete citations from the list, display and add related articles and create relevance lists. Many interactive features occur at client-side, which allow instant feedback without reloading or refreshing the page resulting in a more efficient user experience. PubMed Interact is a highly interactive Web-based search application for MEDLINE/PubMed that explores recent trends in Web technologies like DOM tree manipulation and Ajax. It may become a valuable technical development for online medical search applications.

  12. Patient med gigant umbilikalhernie præoperativt behandlet med botulintoksin A

    DEFF Research Database (Denmark)

    Jensen, Kristian Kiim; Hensler, Margaret; Arnesen, Regnar Bøge

    2017-01-01

    Surgical closure of giant abdominal wall hernia defects remains challenging. We report our initial experience with administration of botulinum toxin type A (BTA) for this approach in a 51-year-old female with a giant primary umbilical hernia and abdominal loss of domain. Four weeks prior to surge...

  13. Epstein-Barr-virus-associeret lymfom hos en patient med colitis ulcerosa i behandling med azathioprin

    DEFF Research Database (Denmark)

    Kofoed, Kristian; Kiszka-Kanowitz, Marianne; Albrectsen, Jens Mørch

    2008-01-01

    A 28 year-old man with ulcerative colitis treated for 10 years with azathioprine (AZA) returned from Central Asia with fever, swollen lymph glands, hepatosplenomegaly, and pancytopenia. He was tested positive for acute Epstein-Barr virus (EBV) infection. Before the final diagnosis of EBV...

  14. Fordeling av verdier med konkurrerende krav

    OpenAIRE

    Sæthre, Morten

    2010-01-01

    Min hensikt er å studere problemstillingen som oppstår når man må fordele begrensede ressurser mellom individer som har eksogene og konkurrerende krav. Jeg vil analytisk beskrive noen populære fordelingsmetoder som har en rekke ønskede egenskaper i denne typen problemstilling. I hovedsak vil jeg ta for meg den aksiomatiske måten å beskrive disse på. I forbindelse med denne analysen har jeg også vært delaktig i et eksperiment der deltakerne møter en analog problemstilling gje...

  15. Lineær programmering med Excel

    DEFF Research Database (Denmark)

    Lynggaard, Peter

    Publikationen giver en introduktion til faget "Lineær programmering". Formulering og løsning bygger på, at modellerne opstilles og løses i et Excel-regneark. Fremgangsmåden er forklaret trin for trin, således at hæftet kan bruges som selvstudiemateriale. Indholdsfortegnelse Generelt om styring og...... planlægning Lineær programmering Excel solveren Fortolkning af udskrifter Degeneration Excel tips Opgaver med løsninger...

  16. Didaktisk kontrakt i matematikklasserom med varierte undervisningsmetoder

    OpenAIRE

    Blaalid, Runar Televik

    2016-01-01

    Master i undervisningsvitenskap, fordypning i matematikkdidaktikk I denne masteravhandlingen undersøker jeg nærmere hvordan den didaktiske kontrakt blir uttrykt i et klasserom med to forskjellige undervisningsmetoder. Fokuset ligger på hvordan forventningene og holdningene til elevene og lærer er i et klasserom som bruker både tradisjonell matematikkundervisning og modellering. Informantene i studien er fire elever i 8.klasse og deres lærer. De blir både observert og intervjuet. Elevene bl...

  17. Manifest for en psykiatri med brugerrespekt

    DEFF Research Database (Denmark)

    Samskabelsesprojekt med psykiatribrugere og pårørende. Psykiatri Manifestet består af forskellige statements om psykiatrien som den opleves set fra brugerperspektiv, og visioner om hvor brugerne ønsker, den skal udvikle sig hen. Brugerne har reageret på Marianne Træbing Sechers invitation via hen...... hendes kontoer på Facebook, Twitter og LinkedIn, samt gennem nedenstående facebooksider og interesseorganisationer. Marianne er ansat som adjunkt på VIA University College og står for videreuddannelse, konsulentarbejde og forskning/udvikling på psykiatriområdet i tilknytning hertil....

  18. MedCast: a discussion support system for cooperative work

    Science.gov (United States)

    Moreno, Ramon A.; Lima, Vinícius; Lopes, Isidro; Gutierrez, Marco A.

    2012-02-01

    The availability of low cost Internet connections and specialized hardware, like webcams and headsets, makes possible the development of solutions for remote collaborative work. These solutions can provide advantages compared to presential meetings, such as: availability of experts on remote locations; lower price compared to presential meetings; creation of online didactic material (e.g. video-classes); richer forms of interaction between participants. These technologies are particularly interesting for continent-sized countries where typically there is a short number of skilled people in remote areas. However, the application of these technologies in medical field represents a special challenge due to the more complex requirements of this area, such as: Provide confidentiality (patient de-identification) and integrity of patient data; Guarantee availability of the system; Guarantee authenticity of data and users; Provide simple and effective user interface; Be compliant with medical standards such as DICOM and HL7. In order to satisfy those requirements a prototype called MedCast is under development whose architecture allows the integration of the Hospital Information System (HIS) with a collaborative tool in compliance with the HIPAA rules. Some of the MedCast features are: videoconferencing, chat, recording of the sessions, sharing of documents and reports and still and dynamic images presentation. Its current version allows the remote discussion of clinical cases and the remote ECG evaluation.

  19. Differential Roles of Transcriptional Mediator Complex Subunits Crsp34/Med27, Crsp150/Med14 and Trap100/Med24 During Zebrafish Retinal Development

    Science.gov (United States)

    Dürr, Katrin; Holzschuh, Jochen; Filippi, Alida; Ettl, Anne-Kathrin; Ryu, Soojin; Shepherd, Iain T.; Driever, Wolfgang

    2006-01-01

    The transcriptional mediator complex has emerged as an important component of transcriptional regulation, yet it is largely unknown whether its subunits have differential functions in development. We demonstrate that the zebrafish mutation m885 disrupts a subunit of the mediator complex, Crsp34/Med27. To explore the role of the mediator in the control of retinal differentiation, we employed two additional mutations disrupting the mediator subunits Trap100/Med24 and Crsp150/Med14. Our analysis shows that loss of Crsp34/Med27 decreases amacrine cell number, but increases the number of rod photoreceptor cells. In contrast, loss of Trap100/Med24 decreases rod photoreceptor cells. Loss of Crsp150/Med14, on the other hand, only slightly reduces dopaminergic amacrine cells, which are absent from both crsp34m885 and trap100lessen mutant embryos. Our data provide evidence for differential requirements for Crsp34/Med27 in developmental processes. In addition, our data point to divergent functions of the mediator subunits Crsp34/Med27, Trap100/Med24, and Crsp150/Med14 and, thus, suggest that subunit composition of the mediator contributes to the control of differentiation in the vertebrate CNS. PMID:16582438

  20. PubMed-EX: a web browser extension to enhance PubMed search with text mining features.

    Science.gov (United States)

    Tsai, Richard Tzong-Han; Dai, Hong-Jie; Lai, Po-Ting; Huang, Chi-Hsin

    2009-11-15

    PubMed-EX is a browser extension that marks up PubMed search results with additional text-mining information. PubMed-EX's page mark-up, which includes section categorization and gene/disease and relation mark-up, can help researchers to quickly focus on key terms and provide additional information on them. All text processing is performed server-side, freeing up user resources. PubMed-EX is freely available at http://bws.iis.sinica.edu.tw/PubMed-EX and http://iisr.cse.yzu.edu.tw:8000/PubMed-EX/.

  1. COSMO-SkyMed and GIS applications

    Science.gov (United States)

    Milillo, Pietro; Sole, Aurelia; Serio, Carmine

    2013-04-01

    Geographic Information Systems (GIS) and Remote Sensing have become key technology tools for the collection, storage and analysis of spatially referenced data. Industries that utilise these spatial technologies include agriculture, forestry, mining, market research as well as the environmental analysis . Synthetic Aperture Radar (SAR) is a coherent active sensor operating in the microwave band which exploits relative motion between antenna and target in order to obtain a finer spatial resolution in the flight direction exploiting the Doppler effect. SAR have wide applications in Remote Sensing such as cartography, surface deformation detection, forest cover mapping, urban planning, disasters monitoring , surveillance etc… The utilization of satellite remote sensing and GIS technology for this applications has proven to be a powerful and effective tool for environmental monitoring. Remote sensing techniques are often less costly and time-consuming for large geographic areas compared to conventional methods, moreover GIS technology provides a flexible environment for, analyzing and displaying digital data from various sources necessary for classification, change detection and database development. The aim of this work si to illustrate the potential of COSMO-SkyMed data and SAR applications in a GIS environment, in particular a demostration of the operational use of COSMO-SkyMed SAR data and GIS in real cases will be provided for what concern DEM validation, river basin estimation, flood mapping and landslide monitoring.

  2. Danske børn med sprogforstyrrelser

    DEFF Research Database (Denmark)

    Sundahl Olsen, Lone

    2013-01-01

    Denne afhandling sætter fokus på en gruppe af danske børn med specifikke sproglige vanskeligheder (SLI). Fælles for disse børn er, at de har en normal IQ og ingen påviste neurologiske, følelsesmæssige, sociale eller fysiske vanskeligheder; men dette til trods tilegner disse børn sig ikke sproget...... lige så problemløst og let som deres jævnaldrende kammerater. SLI er en sproglig udviklingsforstyrrelse, der kan ramme både ekspressiv og receptivt sprog. Tværsproglig forskning viser, at SLI eksisterer på tværs af forskellige sprog og er veldokumenteret for børn, der tilegner sig engelsk, tysk......, italiensk, svensk og hebræisk osv. Det specifikke udfald af SLI afviger dog fra sprog til sprog, og der er på nuværende tidspunkt ikke udført systematisk forskning, der dokumenterer det specifikke udfald af SLI for danske børn. De primære mål med denne ph.d.-afhandling var at undersøge:  Grammatiske...

  3. MedAustron board visits CERN

    CERN Multimedia

    CERN Bulletin

    On 14 October, the board of EBG MedAustron, which is overseeing the construction of Austria’s hadron therapy centre, visited CERN. The visit recognized the relationship of shared knowledge, technology and training between CERN and MedAustron.   Normal.dotm 0 0 1 17 98 cern 1 1 120 12.0 0 false 18 pt 18 pt 0 0 false false false /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin-top:0cm; mso-para-margin-right:0cm; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0cm; line-height:115%; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Times New Roman"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin;} ...

  4. Børn i familier med alkoholmisbrug

    DEFF Research Database (Denmark)

    Zobbe, Karen; Ertmann, Bo

    Pilotundersøgelsen i Græsted-Gilleleje Kommune er en empirisk undersøgelse, hvis mål er at få dokumenteret og indsamlet kvalificeret viden om en eventuel gråzone bestående af børn, der vokser op i familier med et alkoholmisbrug, uden der er iværksat kommunale støtteforanstaltninger hertil. Denne...... viden er essentiel som grundlag for en forstærket indsats, netop fordi denne gruppe børns vilkår er omgivet af barrierer og tabuer både internt i familierne, men også i relationerne til omgivelserne.Undersøgelsen dokumenterer, at der findes en gråzone af børn i familier med alkoholmisbrug, som ikke...... modtager kommunal hjælp. Pilotundersøgelsen peger også på, at organisatoriske problemstillinger har været begrænsende for iværksættelsen af tiltag over for misbrugsfamilier. Også på det holdningsmæssige plan kan der af pilotundersøgelsen udledes store forskelle i egen og andres opfattelse af, hvilke...

  5. MED23-associated refractory epilepsy successfully treated with the ketogenic diet.

    Science.gov (United States)

    Lionel, Anath C; Monfared, Nasim; Scherer, Stephen W; Marshall, Christian R; Mercimek-Mahmutoglu, Saadet

    2016-09-01

    We report a new patient with refractory epilepsy associated with a novel pathogenic homozygous MED23 variant. This 7.5-year-old boy from consanguineous parents had infantile onset global developmental delay and refractory epilepsy. He was treated with the ketogenic diet at 2.5 years of age and became seizure free on the first day. He had microcephaly and truncal hypotonia. His brain MRI showed delayed myelination and thin corpus callosum. He was enrolled in a whole exome sequencing research study, which identified a novel, homozygous, likely pathogenic (c.1937A>G; p.Gln646Arg) variant in MED23. MED23 is a regulator of energy homeostasis and glucose production. Liver-specific Med23-knockout mice showed reduced liver gluconeogenesis and lower blood glucose levels compared to control mice. This is the first patient with documented refractory epilepsy caused by a novel homozygous pathogenic variant in MED23 expanding the phenotypic spectrum. Identification of the underlying genetic defect in MED23 sheds light on the possible mechanism of complete response to the ketogenic diet in this child. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  6. Ødelæg alt muligt med et bogstav

    DEFF Research Database (Denmark)

    Konzack, Lars

    2017-01-01

    En gang imellem griber en raptus SoMe-Danmark, og så fyldes alles feed med samme slags indhold. Senest overspringshandlede vi med hashtagget #oedelaeg1filmed1bogstav - og alle mulige afledninger af det....

  7. Bygningsdele med celluloseuld og høruld

    DEFF Research Database (Denmark)

    Hansen, Ernst Jan de Place

    2001-01-01

    Resume af rapport med eksempler på bygningsdele med papir- eller hørisolering, der overholder bygningsreglementerne, udarbejdet af Dansk Brandteknisk Institut under Energistyrelsens udviklingsprogram "Miljø- og arbejdsmiljøvenlig isolering"...

  8. Metodeudvikling af hjælp til familier med børn med handicap

    DEFF Research Database (Denmark)

    Henriksen, Kirsten; Nørregård, Birgitte

    2000-01-01

    Et undersøgelses- og metodeudviklingsprojekt i relation til forældre til børn med handicap, der passer deres barn i hjemmet. Projektet var finansieret af satspuljemidler. projektet bestod af en række delprojekter, hvis resultater samt anbefalinger til Socialministeriet er samlet i denne evaluerin......Et undersøgelses- og metodeudviklingsprojekt i relation til forældre til børn med handicap, der passer deres barn i hjemmet. Projektet var finansieret af satspuljemidler. projektet bestod af en række delprojekter, hvis resultater samt anbefalinger til Socialministeriet er samlet i denne...

  9. Mindfulness som smertehåndteringsredskab for kvinder med endometriose

    DEFF Research Database (Denmark)

    Jensen, Mette Kold; Vedsted-Hansen, Hanne; Hansen, Tia G. B.

    2011-01-01

    Endometriose er en kronisk underlivssygdom med smerter og en række afledte problemer, som ikke nødvendigvis kan behandles med lægelige tiltag. Artiklen argumenterer for, at en mindfulness-baseret tilgang med fokus på smertehåndtering kan anvendes til denne klientgruppe. I vestlig terapeutisk samm...

  10. PubMed Medical Publications From Libya | Bakoush | Libyan ...

    African Journals Online (AJOL)

    Medical research and publications are the back-bone for advancing the medical field. We identified the PubMed medical publications that are affiliated with Libya to shed some light on the contribution of this country's medical community to the PubMed database. All publications affiliated with Libya in the PubMed were ...

  11. Forsøg med brobygning til EUD

    DEFF Research Database (Denmark)

    Katznelson, Noemi; Görlich, Anne; Hansen, Niels-Henrik Møller

    En evaluering af 12 projekter, som Arbejdsmarkedsstyrelsen har igangsat i samarbejde med Undervisningsministeriet. De 12 projekter har til hensigt at hjælpe unge på kontanthjælp i gang med en ordinær uddannelse. Der er tale om en midtvejsevaluering , hvorved målet med evalueringen er at give de...

  12. Samtidig iltbehandling ved anstrengelsesudløst hypoksæmi forbedrer den fysiske formåen og reducerer åndenød hos patienter med KOL

    DEFF Research Database (Denmark)

    Kjeldgaard, Peter; Ringbæk, Thomas; Lange, Peter

    2011-01-01

    Many chronic obstructive pulmonary disease patients suffer from dyspnoea and reduced physical abilities. Some of the patients exhibit desaturation during physical exercise. Few studies have examined if oxygen therapy during physical exercise can relieve symptoms and improve outcomes of pulmonary...... rehabilitation. These studies show that oxygen therapy during exercise results in significant improvement in exercise capacity. Yet it is not possible to draw a clear conclusion regarding the effects of more prolonged (weeks) treatment. The studies are in general small and of poor methodological quality....

  13. Understanding the inverse care law

    DEFF Research Database (Denmark)

    Pedersen, Anette Fischer; Vedsted, Peter

    2014-01-01

    Udbrændthed er et stigende problem blandt alment praktiserende læger i Danmark. Dette studie viser, at alment praktiserende læger med en stor andel af socialt udsatte patienter på deres liste har større risiko for at være udbrændte sammenlignet med alment praktiserende læger med en lille andel af...

  14. The MEDIATOR genes MED12 and MED13 control Arabidopsis root system configuration influencing sugar and auxin responses.

    Science.gov (United States)

    Raya-González, Javier; López-Bucio, Jesús Salvador; Prado-Rodríguez, José Carlos; Ruiz-Herrera, León Francisco; Guevara-García, Ángel Arturo; López-Bucio, José

    2017-09-01

    Arabidopsis med12 and med13 mutants exhibit shoot and root phenotypes related to an altered auxin homeostasis. Sucrose supplementation reactivates both cell division and elongation in primary roots as well as auxin-responsive and stem cell niche gene expression in these mutants. An analysis of primary root growth of WT, med12, aux1-7 and med12 aux1 single and double mutants in response to sucrose and/or N-1-naphthylphthalamic acid (NPA) placed MED12 upstream of auxin transport for the sugar modulation of root growth. The MEDIATOR (MED) complex plays diverse functions in plant development, hormone signaling and biotic and abiotic stress tolerance through coordination of transcription. Here, we performed genetic, developmental, molecular and pharmacological analyses to characterize the role of MED12 and MED13 on the configuration of root architecture and its relationship with auxin and sugar responses. Arabidopsis med12 and med13 single mutants exhibit shoot and root phenotypes consistent with altered auxin homeostasis including altered primary root growth, lateral root development, and root hair elongation. MED12 and MED13 were required for activation of cell division and elongation in primary roots, as well as auxin-responsive and stem cell niche gene expression. Remarkably, most of these mutant phenotypes were rescued by supplying sucrose to the growth medium. The growth response of primary roots of WT, med12, aux1-7 and med12 aux1 single and double mutants to sucrose and application of auxin transport inhibitor N-1-naphthylphthalamic acid (NPA) revealed the correlation of med12 phenotype with the activity of the auxin intake permease and suggests that MED12 acts upstream of AUX1 in the root growth response to sugar. These data provide compelling evidence that MEDIATOR links sugar sensing to auxin transport and distribution during root morphogenesis.

  15. MedAustron-Project overview and status

    CERN Document Server

    Benedikt, M

    2011-01-01

    MedAustron is the Austrian ion therapy and research centre, presently under construction in Wiener Neustadt, Austria. The facility is based on a synchrotron which will deliver proton beams with kinetic energies up to 250 MeV and carbon ion beams up to 400 MeV/nucleon for clinical applications. In addition to the clinical applications, the accelerator will provide beams for nonclinical research in the fields of medical radiation physics, radiation biology and experimental physics with a proton energy range extended beyond medical requirements to 800 MeV. An overview is given on the historical development of the project. The main design features of the accelerator facilities and medical facilities are presented and the actual status of the project is summarized.

  16. Små dimser med store potentialer

    DEFF Research Database (Denmark)

    Mikkelsen, Bent Egberg; Dobroczynski, Michal; Gade, Rikke

    2015-01-01

    Fødevare- og medialogiforskere på Aalborg Universitet har de seneste år udviklet og testet en række intelligente enheder. Fælles for dem er, at de er små og kan håndtere store mængder af data om forbrugernes adfærd. Et eksempel er FoodScape Tracker, som i realtid samarbejder med forbrugeren om, h......, hvad denne spiser. En anden ny enhed er Virtual Food Choice Simulator, som virtuelt kan simulere fødevareomgivelser i form af buffeter og supermarkeder uden udgifter til ombygning og fødevarer, og derved vise, hvad forbrugerne ser og ikke ser....

  17. The MedAustron Accelerator Control System

    CERN Document Server

    Gutleber, J; Marchhart, M; Torcato de Matos, C; Dedic, J; Moser, R

    2011-01-01

    This paper presents the architecture and design of the MedAustron accelerator control system. This ion therapy and research facility is currently under construction in Wr. Neustadt, Austria. The accelerator and its control system are designed at CERN. This class of machine is characterized by rich sets of configuration data, real-time reconfiguration needs and high stability requirements. The machine is operated according to a pulse-to-pulse modulation scheme. Each beam cycle is described in terms of ion type, energy, beam dimensions, intensity and spill length. The control system is based on a multi-tier architecture with the aim to achieve a clear separation between front-end devices and their controllers. In-house developments cover a main timing system, a light-weight layer to standardize operation and communication of front-end controllers, fast and slow control of power converters and a procedure programming framework for automating high-level control and data analysis tasks.

  18. Pilotstudie: skriftligt arbejde med egen studiekompetence

    DEFF Research Database (Denmark)

    Christensen, Torben Spanget

    2009-01-01

    Det internationale område (dio) er et skriftligt projektarbejde i hhx. Det radikalt nye i dio'en i forhold til traditionelt skriftligt projektarbejde er, at eleven eksplicit skal arbejde med sin egen studiekompetence. Elevens arbejde skal munde ud i en rapport, som har fire bestanddele, dels en...... tværgående forløb, studieområdet (SO), som dio'en er afslutningen på. I artiklen opstilles nogle refleksionsmodeller, som kan benyttes i alle former for fællesfaglig vejledning af eleverne og der gives et bud på nogle bedømmelseskriterier for fællesfaglige projektopgaver....

  19. PubMed had a higher sensitivity than Ovid-MEDLINE in the search for systematic reviews.

    Science.gov (United States)

    Katchamart, Wanruchada; Faulkner, Amy; Feldman, Brian; Tomlinson, George; Bombardier, Claire

    2011-07-01

    To compare the performance of Ovid-MEDLINE vs. PubMed for identifying randomized controlled trials of methotrexate (MTX) in patients with rheumatoid arthritis (RA). We created search strategies for Ovid-MEDLINE and PubMed for a systematic review of MTX in RA. Their performance was evaluated using sensitivity, precision, and number needed to read (NNR). Comparing searches in Ovid-MEDLINE vs. PubMed, PubMed retrieved more citations overall than Ovid-MEDLINE; however, of the 20 citations that met eligibility criteria for the review, Ovid-MEDLINE retrieved 17 and PubMed 18. The sensitivity was 85% for Ovid-MEDLINE vs. 90% for PubMed, whereas the precision and NNR were comparable (precision: 0.881% for Ovid-MEDLINE vs. 0.884% for PubMed and NNR: 114 for Ovid-MEDLINE vs. 113 for PubMed). In systematic reviews of RA, PubMed has higher sensitivity than Ovid-MEDLINE with comparable precision and NNR. This study highlights the importance of well-designed database-specific search strategies. Copyright © 2010 Elsevier Inc. All rights reserved.

  20. First Turkish Experience with the MicroMed DeBakey VAD®

    OpenAIRE

    Kucukaksu, Deniz Suha; Sener, Erol; Undar, Akif; Noon, George P.; Tasdemir, Oguz

    2003-01-01

    Mechanical bridging to cardiac transplantation with a ventricular assist device may be a life-saving procedure for patients with end-stage heart failure. Here we report our 3 cases of patients implanted with the MicroMed DeBakey VA® (ventricular assist device). Three male patients, aged 37, 41, and 40, had end-stage left heart failure due to idiopathic cardiomyopathy and were listed for cardiac transplantation. They had progressive hemodynamic deterioration. Although Patient 1 underwent surge...

  1. Minimal erythema response (MED to solar simulated irradiation in normal Indian skin

    Directory of Open Access Journals (Sweden)

    Mehta Rai Vandana

    2004-09-01

    Full Text Available BACKGROUND: Phototesting is an essential tool in the investigation of photodermatoses. AIMS: The main aim was to study the cutaneous response to UVR in terms of minimal erythema dose (MED to both UVA and UVB in normal Indian subjects with a solar simulator and to study the relationship of skin type to MED. METHODS: One hundred healthy volunteers not on any medication and without any history of photodermatoses were phototested using a solar simulator with whole spectrum irradiation (UVA, UVB and visible light and only visible and UVA radiation. The tested areas were marked with gentian violet and readings were taken after 24 hrs. RESULTS: Of the 100 volunteers, 48% were males and 52% were females, with a mean age of 36.6 ± 11.6 yrs. The most common skin type among Indians was type 5 (46% followed by type 4 (41%. The mean MED for UVB was 61.5 ± 17.25J/cm2. The MED for UVA could not be determined as none of the patients showed any erythema after irradiation for 45 minutes. CONCLUSIONS: As the MED is found to be low in idiopathic acquired photodermatoses, the MED in the normal population could serve as a baseline data in the investigation.

  2. Searching PubMed during a pandemic.

    Directory of Open Access Journals (Sweden)

    Ole Norgaard

    Full Text Available BACKGROUND: The 2009 influenza A(H1N1 pandemic has generated thousands of articles and news items. However, finding relevant scientific articles in such rapidly developing health crises is a major challenge which, in turn, can affect decision-makers' ability to utilise up-to-date findings and ultimately shape public health interventions. This study set out to show the impact that the inconsistent naming of the pandemic can have on retrieving relevant scientific articles in PubMed/MEDLINE. METHODOLOGY: We first formulated a PubMed search algorithm covering different names of the influenza pandemic and simulated the results that it would have retrieved from weekly searches for relevant new records during the first 10 weeks of the pandemic. To assess the impact of failing to include every term in this search, we then conducted the same searches but omitted in turn "h1n1," "swine," "influenza" and "flu" from the search string, and compared the results to those for the full string. PRINCIPAL FINDINGS: On average, our core search string identified 44.3 potentially relevant new records at the end of each week. Of these, we determined that an average of 27.8 records were relevant. When we excluded one term from the string, the percentage of records missed out of the total number of relevant records averaged 18.7% for omitting "h1n1," 13.6% for "swine," 17.5% for "influenza," and 20.6% for "flu." CONCLUSIONS: Due to inconsistent naming, while searching for scientific material about rapidly evolving situations such as the influenza A(H1N1 pandemic, there is a risk that one will miss relevant articles. To address this problem, the international scientific community should agree on nomenclature and the specific name to be used earlier, and the National Library of Medicine in the US could index potentially relevant materials faster and allow publishers to add alert tags to such materials.

  3. Dyrkning af jatropha blandt småbønder i Mozambique - En strategi til reduceret CO2-udledning og lokal udvikling?

    DEFF Research Database (Denmark)

    Rasmussen, Laura Vang

    2010-01-01

    I Cabo Delgado-regionen i det nordlige Mozambique er småbønder inden for de sidste tre år begyndt at dyrke biobrændselsafgrøden jatropha. Bønderne har plantet jatrophatræer som hække langs de eksisterende majsmarker. Da dyrkningen af jatropha anses for en strategi til at skabe lokal udvikling i...... området, ønsker bønderne imidlertid at ekspandere deres areal med jatropha.Ekspansionen af jatropha-arealet vil med al sandsynlighed ske ved, at bønderne omlægger eksisterende skovarealer til jatropha. Dette kan dog have omfattende negative konsekvenser for miljøet, idet en skovrydning vil medføre øget CO...

  4. Arbeta med rangordningsövningar

    Directory of Open Access Journals (Sweden)

    Johan Larsson

    2011-03-01

    Full Text Available Som lärare söker man alltid efter nya undervisningsformer och övningar som ger bättre förutsättningar för studenternas lärande. Ett exempel på detta är rangordningsövningar. Rangordningsövningarna bygger på variation och jämförelse. Läraren väljer vilka egenskaper som varieras och kan rikta studenternas uppmärksamhet mot just de kritiska aspekter man vill uppmärksamma. Under 2010 har vi arbetat med ett pedagogiskt projekt vid Uppsala Universitet där rangordningsövningar prövats i flera olika naturvetenskapliga ämnen. Målet har varit att introducera, utveckla och pröva rangordningsövningar på svenska, där övningarna också breddats, utvecklats och kopplats till aktuell lärandeteori. Rangordningsövningar har visat sig värdefulla inom  fysik, biologi, kemi och geologi där de visat sig fungera i flera olika studentaktiverande sammanhang, t.ex. som aktiverande moment under föreläsningar, som uppgifter under laborationer och fältövningar, under räkneövningar och vid examination. Rangordningsövningarna har också visat sig fungera som utgångspunkt för mer kvalitativa vetenskapliga resonemang.

  5. Sygemeldte og førtidspensionister med handicap

    DEFF Research Database (Denmark)

    Tørslev, Mette Kirstine; Weibel, Kristina; Høgelund, Jan

    2010-01-01

    Dette arbejdspapir belyser udvalgte jobcentermedarbejderes erfaringer med og perspektiver på beskæftigelsesindsatsen for sygedagpengemodtagere og førtidspensionister med handicap. Undersøgelsen er gennemført i tre jobcentre, hvor der er foretaget interview med sagsbehandlere, virksomhedskonsulenter...... sygedagpengemodtagere og førtidspensionister med handicap igangsat af Vidensnetværket, som er forankret i Danske Handicaporganisationer. Arbejdspapiret er udarbejdet af forskningsassistent, cand.mag. (antropologi) Mette Kristine Tørslev, forskningsassistent, cand.scient.soc. Kristina Weibel og seniorforsker, cand...

  6. Idiopatiske skolioser behandlet med Boston-korset

    DEFF Research Database (Denmark)

    Andersen, M O; Andersen, G R; Kruuse, A M

    1993-01-01

    It is well known that Boston bracing may stop progression in many patients with minor curves. One hundred and thirty-eight patients were treated with the Boston brace for idiopathic scoliosis. Age was 14.1 +/- 1.6 years at the time of bracing, and the length of time spent in the brace was 2.6 +/- 1.......0 years. The major curve at the time of bracing was 39 +/- 10 degrees, and 36 +/- 11 degrees at the time of follow-up in the patients who completed bracing. Thirty-six patients progressed, and were later fused. None of the patients with the apex of the curve between T11 and L1 required spinal fusion (p...

  7. Mars 2020 Entry, Descent and Landing Instrumentation (MEDLI2)

    Science.gov (United States)

    Bose, Deepak; Wright, Henry; White, Todd; Schoenenberger, Mark; Santos, Jose; Karlgaard, Chris; Kuhl, Chris; Oishi, TOmo; Trombetta, Dominic

    2016-01-01

    This paper will introduce Mars Entry Descent and Landing Instrumentation (MEDLI2) on NASA's Mars2020 mission. Mars2020 is a flagship NASA mission with science and technology objectives to help answer questions about possibility of life on Mars as well as to demonstrate technologies for future human expedition. Mars2020 is scheduled for launch in 2020. MEDLI2 is a suite of instruments embedded in the heatshield and backshell thermal protection systems of Mars2020 entry vehicle. The objectives of MEDLI2 are to gather critical aerodynamics, aerothermodynamics and TPS performance data during EDL phase of the mission. MEDLI2 builds up the success of MEDLI flight instrumentation on Mars Science Laboratory mission in 2012. MEDLI instrumentation suite measured surface pressure and TPS temperature on the heatshield during MSL entry into Mars. MEDLI data has since been used for unprecedented reconstruction of aerodynamic drag, vehicle attitude, in-situ atmospheric density, aerothermal heating, transition to turbulence, in-depth TPS performance and TPS ablation. [1,2] In addition to validating predictive models, MEDLI data has highlighted extra margin available in the MSL forebody TPS, which can potentially be used to reduce vehicle parasitic mass. MEDLI2 expands the scope of instrumentation by focusing on quantities of interest not addressed in MEDLI suite. The type the sensors are expanded and their layout on the TPS modified to meet these new objectives. The paper will provide key motivation and governing requirements that drive the choice and the implementation of the new sensor suite. The implementation considerations of sensor selection, qualification, and demonstration of minimal risk to the host mission will be described. The additional challenges associated with mechanical accommodation, electrical impact, data storage and retrieval for MEDLI2 system, which extends sensors to backshell will also be described.

  8. Musikterapiens appel og virkefelt. Et interaktionsteoretisk perspektiv på et prøveforløb med en teenagepige fra børnepsykiatrien med diagnosen infantil autisme

    Directory of Open Access Journals (Sweden)

    Ulla Holck

    2003-03-01

    Full Text Available Med udgangspunkt i Inge Nygaard Pedersens artikel om musikterapi med en teenagepige med diagnosen infantil autisme, diskuteres musikterapiens appel og virkefelt. Ud fra en interaktionsteoretisk vinkel fremhæves handlingsaspektet i musikterapi - og herunder balancenmellem kendt og ukendt, forventingsstrukturer samt opbygning af en fælles interaktionshistorie mellem patient og terapeut. Endelig drøftes betydningen af musiks identitetsskabende funktion for børn og unge, samt aspekter af det musikalske samspils styrke i forhold til at opbygge en terapeutisk alliance.

  9. MED, COMP, multilayered and NEIN: an overview of multiple epiphyseal dysplasia

    Energy Technology Data Exchange (ETDEWEB)

    Lachman, Ralph S. [International Skeletal Dysplasia Registry, UCLA School of Medicine, Radiological Services, Department of Pediatrics, Los Angeles, CA (United States); International Skeletal Dysplasia Registry, Los Angeles, CA (United States); Krakow, Deborah; Cohn, Daniel H.; Rimoin, David L. [International Skeletal Dysplasia Registry, UCLA School of Medicine, Radiological Services, Department of Pediatrics, Los Angeles, CA (United States)

    2005-02-01

    This overview covers the group of disorders that presents radiographically as multiple epiphyseal dysplasia (MED). The disorders include ''classic MED'' (Ribbing and Fairbank types): MED that is caused by mutations in the cartilage oligomeric matrix protein (COMP), type IX collagen, and matrilin 3 genes (MATN3); and MED with multilayered patella, brachydactyly, and clubbed feet resultant from mutations in gene defect diastrophic dysplasia (DTDST). The recently identified gene/molecular abnormalities in these disorders have made more exact identification possible in many cases, although clinical testing is not always available. However, there are specific radiographic findings that allow the accurate diagnosis to be made, thus potentially guiding which molecular defect(s) should be investigated. The modes of inheritance of these distinct MED conditions are not identical. When a specific diagnosis is made, proper genetic counseling as well as prognostication, management issues and complications can be delineated to the patient and family. This review will include the mechanics of diagnostic and molecular triage for these disorders. (orig.)

  10. C-Med 100, a hot water extract of Uncaria tomentosa, prolongs lymphocyte survival in vivo.

    Science.gov (United States)

    Akesson, Ch; Pero, R W; Ivars, F

    2003-01-01

    Water extracts of the bark of Uncaria tomentosa, a vine indigenous to South America, has been used for generations as an "immuno modulator". To understand the basis of this immuno modulatory effect we fed mice in their drinking water with C-Med 100, which is a commercially available water extract from Uncaria tomentosa. We found a dose-dependent increase in spleen cell numbers in the supplemented mice, but the proportions of B cells, T cells, NK cells, granulocytes, and memory lymphocytes were normal. However, there were no detectable changes of the lymphoid architecture of the spleen even after long-term treatment. Further, when C-Med 100 treatment was interrupted the cellularity returned to normal level within four weeks. The increased number of lymphocytes was most likely not due to increased production because C-Med 100 did not have any significant effect on precursor cells nor on the accumulation of recent thymic emigrants in the spleen. We conclude that accumulation is most likely due to prolonged cell survival, because adoptive transfer experiments demonstrated that C-Med 100 treatment significantly prolonged lymphocyte survival in peripheral lymphoid organs, without increasing their proliferation rate. Since the accumulation was reversible and without detectable pathological effects, these results suggest the use of C-Med 100 as a potential agent for clinically accelerating the recovery of patients from leukopenia.

  11. TeleMed: Wide-area, secure, collaborative object computing with Java and CORBA for healthcare

    Energy Technology Data Exchange (ETDEWEB)

    Forslund, D.W.; George, J.E.; Gavrilov, E.M.

    1998-12-31

    Distributed computing is becoming commonplace in a variety of industries with healthcare being a particularly important one for society. The authors describe the development and deployment of TeleMed in a few healthcare domains. TeleMed is a 100% Java distributed application build on CORBA and OMG standards enabling the collaboration on the treatment of chronically ill patients in a secure manner over the Internet. These standards enable other systems to work interoperably with TeleMed and provide transparent access to high performance distributed computing to the healthcare domain. The goal of wide scale integration of electronic medical records is a grand-challenge scale problem of global proportions with far-reaching social benefits.

  12. Salmonella-infektion kompliceret med akut nyreinsufficiens

    DEFF Research Database (Denmark)

    Thøgersen, Thøger; Jensen, Jørgen Erik; Jespersen, Bente

    2003-01-01

    Acute renal failure is a known complication to Salmonella gastroenteritis, and patients with chronic renal failure or impaired host defence are at increased risk. In the two presented cases there had been a few days of gastroenteritis before the hospitalisation, but the only symptoms...... at the admission were fatigue and dyspnoea. In both cases severe uraemia had developed and the patients and their physicians did not expect the episode of gastroenteritis to be the only etiology of acute renal failure. Both patients had normal renal histology and Salmonella was grown in their faeces. Subsequently...

  13. Psoriasis er associeret med type 2-diabetes

    DEFF Research Database (Denmark)

    Gyldenl�ve, Mette; Knop, Filip Krag; Vilsb�ll, Tina

    2013-01-01

    Psoriasis is a chronic inflammatory skin disease with a global prevalence of 2-3%. In recent years it has been established that patients with psoriasis carry an increased risk of type 2 diabetes, but the underlying pathophysiological mechanisms remain unclear. The association is most likely due...... to a combination of shared genes, immunoinflammatory mechanisms and a number of diabetes risk factors in patients with psoriasis. The current review summarises the evidence in the field and calls for attention on diabetes risk assessment, preventive measures and treatment in patients with psoriasis....

  14. Dysfunktionel vejrtrækning hos patienter med astma

    DEFF Research Database (Denmark)

    Andreasson, Karen Hjerrild; Skou, Søren T; Porsbjerg, Celeste

    2017-01-01

    Dysfunctional breathing (DB) is a common comorbidity in adults with incomplete asthma control. The few available large-scale, randomized studies suggest efficacy of physiotherapy on symptom burden. In this article we discuss the current evidence including the need for systematic description...... of physiotherapeutic interventions. We also describe how access to physiotherapy service for DB (with or without asthma) is highly heterogeneous in Denmark, and that there is a need for increasing awareness of physiotherapy implementation for and research in DB (with or without concomitant asthma)....

  15. Immuncheckpointantistoffer øger overlevelsen for patienter med metastatisk melanom

    DEFF Research Database (Denmark)

    Fløe, Louise Elkjær; Svane, Inge Marie; Bastholt, Lars

    2016-01-01

    The incidence of melanoma is rising and until recently, metastatic melanoma had a poor survival prognosis. Manipulation of two newly discovered immune pathways have shown impressive results. The first is treatment with anti-cytotoxic T-lymphocyte-antigen (CTLA)-4 antibody which blocks the inhibit......The incidence of melanoma is rising and until recently, metastatic melanoma had a poor survival prognosis. Manipulation of two newly discovered immune pathways have shown impressive results. The first is treatment with anti-cytotoxic T-lymphocyte-antigen (CTLA)-4 antibody which blocks...... the inhibitory receptor CTLA-4. The other is anti-programmed cell death (PD)-1 antibody which blocks the inhibitory receptor PD-1 on T-cells. Thereby, the T-cells are kept activated and able to attack cancer cells....

  16. Laktatacidose som komplikation til inhalationsbehandling hos patient med astmaeksacerbation

    DEFF Research Database (Denmark)

    Ekelund, Kim; Følsgaard, Søren Lars

    2013-01-01

    We present a case of severe lactic acidosis due to exacerbation of asthma in presence of normal tissue perfusion and oxygenation in a 35-year-old woman with poorly controlled asthma. After admission, she was treated continuously with inhalation of salbutamol (a beta-agonist) resulting in lactic...... acidosis, which was misinterpreted as treatment failure. The lactic acidosis reversed on discontinuation of the inhalation therapy. Although lactic acidosis is a rare complication to inhalation of beta-agonists, it is important for the clinicians to recognize this....

  17. Bisfosfonatassocieret osteonekrose i kaeberne hos patienter med myelomatose

    DEFF Research Database (Denmark)

    Lund, Thomas; Gregersen, Henrik; Vangsted, Annette

    2009-01-01

    of bisphosphonate therapy and with the potency of the used bisphosphonate. BON usually develops after tooth extraction or other oral surgery, and has proven difficult to treat. Optimal dental hygiene should be ensured prior to treatment initiation where possible, and once bisphosphonate treatment is instituted...

  18. Indikationer for radioimmunterapi til patienter med non-Hodgkins lymfom

    DEFF Research Database (Denmark)

    Frølund, Ulf Christian; Hansen, Per Boye

    2011-01-01

    Radioimmunotherapy is a well-known treatment for non-Hodgkin's lymphoma. (90)yttrium (Y)-ibritumomab-tiuxetan consists of a radioisotope conjugated to a monoclonal anti-cluster of differentiation 20 antibody, which is targeted against B-lymphocytes. Initially the treatment indication was relapse...... of low-grade non-Hodgkin's lymphoma. However, (90)Y-ibritumomab-tiuxetan has later been used in clinical trials in the treatment of other types of non-Hodgkin's lymphoma and prior to stem cell transplantation. Based on the literature this systematic review aims to throw light on the future possibilities...

  19. Peritoneal tuberkulose hos patient med formodet dissemineret ovariecancer

    DEFF Research Database (Denmark)

    Madsen, Lone Wulff; Neumann, Gudrun; Pedersen, Court

    2012-01-01

    imaging) supported this suspicion. Peritoneal biopsy from laparoscopy showed granulomas with central necrosis. Microscopy, culture and polymerase chain reaction from biopsy samples were negative for Mycobacterium tuberculosis. Follow-up with a CT scan after six months of full tuberculosis treatment showed...... normal conditions. Peritoneal tuberculosis is a diagnostic challenge, but should be considered in case of immigrants from high-risk areas....

  20. Ambulanceservice til patienter med akutte hjertelidelser i Danmark - en status

    DEFF Research Database (Denmark)

    Lybecker, H; Larsen, C F; Nielsen, J R

    1990-01-01

    In 1985, the Danish Board of Health published a review of the therapeutic value of heart ambulances. A report is presented here concerning the extent to which prehospital treatment of cardiac arrest recommended by the Board of Health has been intensified after publication of the review. The preho...... recovery when intensified prehospital treatment of cardiac arrest is employed. Hence legislation steps should be taken to improve pre-hospital treatment of cardiac arrest....

  1. Stressfrakturer af distale fibula hos en patient med osteoporose

    DEFF Research Database (Denmark)

    Schwartz, Frederik; Heerfordt, Ida Marie

    2014-01-01

    We report a case of an 81-year-old osteoporotic woman, who suffered stress fractures of the distal fibula on both sides within a two-year period. The risk factors for stress fractures are reviewed and the importance of a high index of suspicion for stress fractures is emphasized. When a stress fr...

  2. Bisfosfonatassocieret osteonekrose i kaeberne hos patienter med myelomatose

    DEFF Research Database (Denmark)

    Lund, Thomas; Gregersen, Henrik; Vangsted, Annette

    2009-01-01

    of bisphosphonate therapy and with the potency of the used bisphosphonate. BON usually develops after tooth extraction or other oral surgery, and has proven difficult to treat. Optimal dental hygiene should be ensured prior to treatment initiation where possible, and once bisphosphonate treatment is instituted......, oral surgery should be avoided if possible. Udgivelsesdato: 2009-Jan...

  3. Bisfosfonatassocieret osteonekrose i kaeberne hos patienter med myelomatose

    DEFF Research Database (Denmark)

    Lund, Thomas; Gregersen, Henrik; Vangsted, Annette

    2009-01-01

    of bisphosphonate therapy and with the potency of the used bisphosphonate. BON usually develops after tooth extraction or other oral surgery, and has proven difficult to treat. Optimal dental hygiene should be ensured prior to treatment initiation where possible, and once bisphosphonate treatment is instituted......, oral surgery should be avoided if possible. Udgivelsesdato: 2009-Jan-5...

  4. Paraneoplastisk pancytopeni hos en patient med uerkendt lungecancer

    DEFF Research Database (Denmark)

    Hansen, Jakob Werner; Sjö, Lene; Grønbæk, Kirsten

    2014-01-01

    Pancytopenia can be caused by lack of bone marrow function and can have different origins. A 66-year-old woman was admitted with severe sepsis, and the blood results revealed pancytopenia. A bone marrow biopsy was performed, and the primary diagnosis was hypocellular acute myeloid leukaemia with 20......% blasts, but a diagnosis of myelodysplastic syndrome (MDS) was considered. After 30 days without any chemotherapeutic treatment her peripheral blood was normalised. In the meanwhile she was diagnosed with a small cell lung cancer. In this case the MDS-like condition was caused by a paraneoplastic...

  5. Myopati hos en patient i behandling med simvastatin og fluconazol

    DEFF Research Database (Denmark)

    Pedersen, Jens Kristian; Lydolph, Magnus Christian; Somnier, Finn

    2016-01-01

    A 69-year-old female was admitted due to progressive loss of muscle strength following addition of fluconazole to long-term simvastatin treatment. Rhabdomyolysis was suspected and both drugs were discontinued. Forced diuresis was initiated together with a short course of prednisolone. After 21...

  6. CDAPubMed: a browser extension to retrieve EHR-based biomedical literature

    Directory of Open Access Journals (Sweden)

    Perez-Rey David

    2012-04-01

    Full Text Available Abstract Background Over the last few decades, the ever-increasing output of scientific publications has led to new challenges to keep up to date with the literature. In the biomedical area, this growth has introduced new requirements for professionals, e.g., physicians, who have to locate the exact papers that they need for their clinical and research work amongst a huge number of publications. Against this backdrop, novel information retrieval methods are even more necessary. While web search engines are widespread in many areas, facilitating access to all kinds of information, additional tools are required to automatically link information retrieved from these engines to specific biomedical applications. In the case of clinical environments, this also means considering aspects such as patient data security and confidentiality or structured contents, e.g., electronic health records (EHRs. In this scenario, we have developed a new tool to facilitate query building to retrieve scientific literature related to EHRs. Results We have developed CDAPubMed, an open-source web browser extension to integrate EHR features in biomedical literature retrieval approaches. Clinical users can use CDAPubMed to: (i load patient clinical documents, i.e., EHRs based on the Health Level 7-Clinical Document Architecture Standard (HL7-CDA, (ii identify relevant terms for scientific literature search in these documents, i.e., Medical Subject Headings (MeSH, automatically driven by the CDAPubMed configuration, which advanced users can optimize to adapt to each specific situation, and (iii generate and launch literature search queries to a major search engine, i.e., PubMed, to retrieve citations related to the EHR under examination. Conclusions CDAPubMed is a platform-independent tool designed to facilitate literature searching using keywords contained in specific EHRs. CDAPubMed is visually integrated, as an extension of a widespread web browser, within the standard

  7. CDAPubMed: a browser extension to retrieve EHR-based biomedical literature.

    Science.gov (United States)

    Perez-Rey, David; Jimenez-Castellanos, Ana; Garcia-Remesal, Miguel; Crespo, Jose; Maojo, Victor

    2012-04-05

    Over the last few decades, the ever-increasing output of scientific publications has led to new challenges to keep up to date with the literature. In the biomedical area, this growth has introduced new requirements for professionals, e.g., physicians, who have to locate the exact papers that they need for their clinical and research work amongst a huge number of publications. Against this backdrop, novel information retrieval methods are even more necessary. While web search engines are widespread in many areas, facilitating access to all kinds of information, additional tools are required to automatically link information retrieved from these engines to specific biomedical applications. In the case of clinical environments, this also means considering aspects such as patient data security and confidentiality or structured contents, e.g., electronic health records (EHRs). In this scenario, we have developed a new tool to facilitate query building to retrieve scientific literature related to EHRs. We have developed CDAPubMed, an open-source web browser extension to integrate EHR features in biomedical literature retrieval approaches. Clinical users can use CDAPubMed to: (i) load patient clinical documents, i.e., EHRs based on the Health Level 7-Clinical Document Architecture Standard (HL7-CDA), (ii) identify relevant terms for scientific literature search in these documents, i.e., Medical Subject Headings (MeSH), automatically driven by the CDAPubMed configuration, which advanced users can optimize to adapt to each specific situation, and (iii) generate and launch literature search queries to a major search engine, i.e., PubMed, to retrieve citations related to the EHR under examination. CDAPubMed is a platform-independent tool designed to facilitate literature searching using keywords contained in specific EHRs. CDAPubMed is visually integrated, as an extension of a widespread web browser, within the standard PubMed interface. It has been tested on a public dataset

  8. PubMed Medical Publications From Libya | Bakoush | Libyan ...

    African Journals Online (AJOL)

    We also used the same method to obtain data on the PubMed medical publications from Tunisia, Morocco and Yemen. Tunisia had the largest number of PubMed publications among the studied countries: 20.4 publications per million population per year and 7.2 publications per year per one billion US$ GDP. Libya had ...

  9. Psykomotorisk behandling og wellness til personer med demens

    DEFF Research Database (Denmark)

    Stamp, Anne Schinkel; Frausing, Kristian Park

    Rapporten evaluerer projektet Psykomotorisk behandling af personer med demens gennem fokusgruppeinterviews med deltagende studerende og personale fra deltagende centre. Samlet peges der på gavnligt udbytte for de demente beboere samt både personligt og fagligt udbytte for de deltagende studerende...

  10. Spilleregler i musikterapi med børn

    DEFF Research Database (Denmark)

    Holck, Ulla

    2005-01-01

    anvendelse af spilleregler med forskellige børneklientgrupper – alle med en vis udviklingsalder. Udover improvisation viser caseeksemplerne, at der i børnemusikterapi automatisk inddrages en række andre medier og teknikker end dem, man ser i voksenmusikterapien, hvilket bl.a. begrundes i Winnicotts...

  11. Musikterapi med kontakt- og kommunikationssvage børn

    DEFF Research Database (Denmark)

    Frederiksen, Britta Vinkler

    2009-01-01

    I artiklen beskrives, hvordan musikterapi er med til at støtte en målrettet udviklingsproces hos børn, med diagnoser som Asperger syndrom, autisme, opmærksomhedsforstyrrelser, ADHD o.lign. Musikkens kvaliteter beskrives og illustreres gennem vignetter fra terapiforløb, der alle er foregået i Klinik...

  12. Erfaringer med mobning fra barndommen og det levede liv

    DEFF Research Database (Denmark)

    Mathiassen, Charlotte; Viala, Eva Silberschmidt

    2009-01-01

    Gennem analyser af konkret levet liv med mobning i 1950érnes og 1960érnes skoleliv sættes der fokuspå menneskers erfaringer med mobning og deres position i en given historisk og sociokulturel kontekst. På den baggrund argumenteres det, at hvis man som forsker eller praktiker ikke anstrenger sig f...

  13. Professionsetik. Om etiske perspektiver i arbejdet med mennesker

    DEFF Research Database (Denmark)

    Præstegaard, Jeanette

    2013-01-01

    Boganmeldelse af Christoffersen SA (ed) Professionsetik. Om etiske perspektiver i arbejdet med mennesker [Professional ethic. About ethical perspectives in the work with human beings]. Aarhus; Forlaget Klim.......Boganmeldelse af Christoffersen SA (ed) Professionsetik. Om etiske perspektiver i arbejdet med mennesker [Professional ethic. About ethical perspectives in the work with human beings]. Aarhus; Forlaget Klim....

  14. Selvregulering og dyadisk regulering i musikterapi med demensramte

    DEFF Research Database (Denmark)

    Ridder, Hanne Mette Ochsner

    2017-01-01

    Selvregulering er tæt koblet til socialt samvær og følelsesregulering og styres af neuroaffektive processer, der har med empati og stress at gøre. Hvordan vi ældes, og om vi bevarer engagement og motivation, kan have betydning for udvikling af demens. Mennesker med demens vil opleve gradvist at få...

  15. Performance requirements of the MedAustron beam delivery system

    CERN Document Server

    AUTHOR|(CDS)2073034

    The Austrian hadron therapy center MedAustron is currently under construction with patient treatment planned to commence in 2015. Tumors will be irradiated using proton and carbon ions, for which the steeply rising Bragg curve and finite range offer a better conformity of the dose to the geometrical shape of the tumor compared to conventional photon irradiation. The current trend is to move from passive scattering toward active scanning using a narrow pencil beam in order to reach an even better dose conformation and limit the need of patient specific hardware. The quality of the deposited dose will ultimately depend on the performance of the beam delivery chain: beam profile and extraction stability of the extracted beam, accuracy and ramp rate of the scanning magnet power supplies, and precision of the beam monitors used for verifying the delivered dose. With a sharp lateral penumbra, the transverse dose fall-off can be minimized. This is of particular importance in situations where the lesion is adjace...

  16. Maksilrekonstruktion med stilket temporalislap efter maksillektomi

    DEFF Research Database (Denmark)

    Lambertsen, Karin; Bundgaard, Troels

    2009-01-01

    INTRODUCTION: Removal of the maxilla requires adequate restoration of the maxillary structure to replace form and functions, especially vocal and eating functions. A host of reconstructive options are available to restore the maxilla, most of which include free-flap reconstruction. The aim of thi...... developed oro-nasal/antral fistula, witch were later closed using local flaps. CONCLUSION: The follow-up study of the 27 patients showed a most satisfactory result evaluated objectively as well as subjectively using the EORTC questionnaire. Udgivelsesdato: 2009-Aug-17...... of the maxilla using pedicle temporalis muscle flap at the ENT department, Aarhus University Hospital. Follow-up was implemented in 2007. Twenty-seven of 28 patients alive at the time of the follow-up participated in the study. The patients were evaluated objectively as well as subjectively by answering...... the EORTC's standard questionnaire concerning quality of life and functional results. RESULTS: Few patients had complaints and these where mostly minor functional deficits. The most common complaints were slightly impaired mouth opening. One temporalis muscle flap necrotized and was removed. Three patients...

  17. Human mediator subunit MED15 promotes transcriptional activation.

    Science.gov (United States)

    Nakatsubo, Takuya; Nishitani, Saori; Kikuchi, Yuko; Iida, Satoshi; Yamada, Kana; Tanaka, Aki; Ohkuma, Yoshiaki

    2014-10-01

    In eukaryotes, the Mediator complex is an essential transcriptional cofactor of RNA polymerase II (Pol II). In humans, it contains up to 30 subunits and consists of four modules: head, middle, tail, and CDK/Cyclin. One of the subunits, MED15, is located in the tail module, and was initially identified as Gal11 in budding yeast, where it plays an essential role in the transcriptional regulation of galactose metabolism with the potent transcriptional activator Gal4. For this reason, we investigated the function of the human MED15 subunit (hMED15) in transcriptional activation. First, we measured the effect of hMED15 knockdown on cell growth in HeLa cells. The growth rate was greatly reduced. By immunostaining, we observed the colocalization of hMED15 with the general transcription factors TFIIE and TFIIH in the nucleus. We measured the effects of siRNA-mediated knockdown of hMED15 on transcriptional activation using two different transcriptional activators, VP16 and SREBP1a. Treatment with siRNAs reduced transcriptional activation, and this reduction could be rescued by overexpression of HA/Flag-tagged, wild-type hMED15. To investigate hMED15 localization, we treated human MCF-7 cells with the MDM2 inhibitor Nutlin-3, thus inducing p21 transcription. We found that hMED15 localized to both the p53 binding site and the p21 promoter region, along with TFIIE and TFIIH. These results indicate that hMED15 promotes transcriptional activation.

  18. Behandling af Tourettes syndrom med aripiprazol

    DEFF Research Database (Denmark)

    Stenstrøm, Anne Dorte; Sindø, Ingrid

    2008-01-01

    Tourette's syndrome (TS) is a motoric disorder characterised by multiple motor and vocal tics. The treatment for patients with moderate to severe TS includes antipsychotic medication. A case report is described in which a 20 year-old male had taken antipsychotic medication since the age of five......, due to TS. The initial treatment consisted of pimozide and risperidone, both of which had an unsatisfactorily efficacy on tics and side effects in the form of weight gain and sedation. The patient is now treated with aripiprazole and there is a marked reduction of tics and no side effects...

  19. Behandling med kosmetiske bløddelsfyldere

    DEFF Research Database (Denmark)

    Thyssen, Jacob Pontoppidan; Christensen, Lise H; Zachariae, Claus O C

    2007-01-01

    An increasing number of patients undergo soft-tissue augmentation. The quality depends on the applied filler substance, the compliance of the patient and the physician. Long-term adverse reactions are referred to as nodules or granulomas. Nodules following degradable gels and polyacrylamide hydro...... hydrogel are always caused by bacteria. Nodules following inert, hydrophobic silicone gel and combination gels may emerge years after the injection. They are often caused by a low-grade infection with ensuing enhanced fibrosis and treatment requires a specialist....

  20. Behandling af diabetes mellitus med biologiske laegemidler

    DEFF Research Database (Denmark)

    Larsen, Claus Morten; Mandrup-Poulsen, Thomas

    2008-01-01

    Biologic therapeutics are currently not approved for the treatment of patients with type 1 and type 2 diabetes. However, promising results from recent randomized controlled studies suggest that biologic therapeutics have therapeutic potential. This article summarizes the causal steps of the patho......Biologic therapeutics are currently not approved for the treatment of patients with type 1 and type 2 diabetes. However, promising results from recent randomized controlled studies suggest that biologic therapeutics have therapeutic potential. This article summarizes the causal steps...... of the pathogenesis of type 1 and type 2 diabetes which are targeted by biologic therapeutics and reviews the treatment results. Udgivelsesdato: 2008-Jun-9...

  1. Peritoneal tuberkulose kan diagnosticeres med laparoskopi

    DEFF Research Database (Denmark)

    Schwensen, Jakob Ferløv; Bulut, Mustafa; Nordholm-Carstensen, Andreas

    2014-01-01

    and widespread pale nodules were found throughout the peritoneum. Consequently, the patient was diagnosed with peritoneal tuberculosis. This case demonstrates that atypical manifestations of tuberculosis exist in Denmark and that laparoscopy with biopsy can be performed to obtain the diagnosis when suspecting...... peritoneal tuberculosis....

  2. Behandling af diabetes mellitus med biologiske laegemidler

    DEFF Research Database (Denmark)

    Larsen, Claus Morten; Mandrup-Poulsen, Thomas

    2008-01-01

    Biologic therapeutics are currently not approved for the treatment of patients with type 1 and type 2 diabetes. However, promising results from recent randomized controlled studies suggest that biologic therapeutics have therapeutic potential. This article summarizes the causal steps...... of the pathogenesis of type 1 and type 2 diabetes which are targeted by biologic therapeutics and reviews the treatment results. Udgivelsesdato: 2008-Jun-9...

  3. Håndtering af dagliglivet med psoriasis

    DEFF Research Database (Denmark)

    Rasmussen, Gitte Susanne

    2010-01-01

    This study investigates factors that, according to the literature, may impact psoriasis patients’ needs for patient education to support self-management in daily life. The study was carried out as an inte-grative review. This design allows for a combination of diverse methodologies and is well...

  4. Sygeplejerskeadministreret propofolsedation i forbindelse med endoskopi

    DEFF Research Database (Denmark)

    Vilmann, Peter; Hornslet, Pernille; Simmons, Hanne

    2009-01-01

    INTRODUCTION: As an increasing number of therapeutic and diagnostic procedures are performed endoscopically, the demand for sufficient sedation during endoscopy is rising. Propofol sedation administered by nurses (NAPS) has gained increasing popularity. NAPS was introduced at Gentofte Hospital...... in September 2007 after structured training at Roque Valley Surgical Center in Medford, Oregon, USA. The aim of the present study is to present our results with NAPS. MATERIAL AND METHODS: Patients referred for endoscopy were monitored with regard to blood pressure, pulse oxymetry, electrocardiography...... via a nasal tube. Short lasting manual mask ventilation was instituted in five patients. No serious events related to sedation were seen. CONCLUSIONS: NAPS seem to be a suitable method for sedation in endoscopy and should be implemented in Denmark. However, proper training is required in collaboration...

  5. Erfaringer med helsemonitorering for KOLS-pasienter

    Directory of Open Access Journals (Sweden)

    Catharina Bjørkquist

    2015-12-01

    Full Text Available This article analyzes how health monitoring by tablet computer of COPD patients can contribute to safety and coping. The aim is to document and discuss experiences from users and the project team member who is also a nurse, with the use of telecare technology. The study was qualitative, using in-depth interview and short enquetes. Results show that the users increased their understanding of their physical condition and got better control of their illness. Accordingly, they coped better and felt more secure. Their level of activity was hardly affected even though one patient argued that the monitoring helped her adapt the level of activity to her present physical condition. Based on this study, we have, however, no significant indication that health monitoring by the use of tablet computer may reduce hospitalization and readmission rates.

  6. Nyrefunktionen under behandling med angiotensinkonverterende enzymhaemmere

    DEFF Research Database (Denmark)

    Rasmussen, K; Heitmann, M; Nielsen, J I

    1995-01-01

    -inhibitors on renal haemodynamics and kidney function, which may be positive, with preservation of kidney function in diabetic and other chronic nephropathy, or negative, for example in cases with atherosclerotic stenosis of large or small renal arteries. It is concluded, that in cases of diabetic nephropathy an ACE......The use of ACE-inhibitors has increased greatly during the last years. They were first used in treating hypertension, but nowadays cardiac diseases, mainly cardiac failure, are common indications. This means that the drugs are used in the treatment of more elderly patients who often have...... generalised atherosclerosis. This means that the patients must be controlled more often after initiation of treatment, especially concerning kidney function, since treatment with ACE-inhibitors can cause pronounced changes in renal haemodynamics and kidney function. This review focuses on the effects of ACE...

  7. Lungeinfektioner med nontuberkuløse mykobakterier

    DEFF Research Database (Denmark)

    Fløe, Andreas; Hermansen, Thomas Stig; Lillebaek, Troels

    2016-01-01

    In recent decades, an increasing incidence of pulmonary infections with non-tuberculous mycobacteria has been reported, primarily affecting patients with structural lung diseases and/or immunosuppression. In Denmark, approximately 100 new cases of infection with non-tuberculous mycobacteria occur...... yearly, most commonly with Mycobacterium avium complex. Diagnosis is based on clinical, radiological and microbiological criteria. Treatment is difficult, and outcomes are often poor. Antibiotic treatment should be performed by specialists with reference to international guidelines....

  8. Behandling af ideopatisk hypereosinofilt syndrom med imatinib

    DEFF Research Database (Denmark)

    Sørensen, Anne Louise; Larsen, Herdis

    2008-01-01

    We here report a case of idiopathic hypereosinophilic syndrome with prompt response to treatment with imatinib. The patient presented with chest pain, myalgias, fatigue and weakness. Blood tests and bone marrow examination revealed striking eosinophilia. Clonal or reactive disorders were excluded...... by a wide range of diagnostic examinations. Treatment with high-dosis corticosteroids and hydroxyurea had little effect. Additional treatment with imatinib resulted in prompt symptomatic improvement and full haematological remission within five days of therapy. Udgivelsesdato: 2008-Jan-21...

  9. Til julefrokost med Bjørn & Okay

    DEFF Research Database (Denmark)

    Smith-Sivertsen, Henrik

    2012-01-01

    I denne artikel vises med udgangspunkt i en beskrivelse af et specifikt arrangement med det danske danseorkester Bjørn & Okay, hvordan man optræder inden for denne særlige musiktradition. Bjørn & Okays performative udgangspunkt er, at de, trods en status som landskendt orkester med mange hits, i ...... the audience and constantly telling them what to do. At the same time he and the other musicians actively bond with the audience, both onstage and offstage, which helps building the spirit of community, which is the clear goal of the musical performance....

  10. Do we need to change our understanding of anticipatory grief in caregivers?

    DEFF Research Database (Denmark)

    Nielsen, Mette Kjaergaard; Neergaard, Mette Asbjoern; Jensen, Anders Bonde

    2016-01-01

    Sorgsymptomer under sygdomsforløbet blandt pårørende til terminalt syge patienter har været forbundet med både forværret og forbedret sorgreaktion efter dødsfaldet. Dette systematiske review viste, at pårørende med svær grad af sorgsymptomer før patientens død har øget risiko for at udvikle alvor...

  11. Kvalitet i almen praksis?

    DEFF Research Database (Denmark)

    Lippert, Maria Laura; Dyhr, Lise

    2015-01-01

    Artiklen beskriver en undersøgelse, der afdækkede, hvad der kan ske med læge-patient-samtalen, når der i kvalitetssikringsøjemed popper små skærmbilleder op med spørgsmål på lægens PC, der præsenterer faste standarder for indhold og forløb. Konsultationer blandt læger, som anvendte og udfyldte...

  12. Visse analgetika kan med fordel anvendes transdermalt

    DEFF Research Database (Denmark)

    Jensen, Niels Martin; Holmgaard, Rikke; Nielsen, Jesper Bo

    2015-01-01

    Many patients experience acute or chronic pain. The options for treating these pain conditions are many, and particularly products for topical application are gaining ground. NSAID for topical use is a good alternative to NSAID administered orally due to less systemic side effects. Transdermally...... delivered opioids have proven to be as effective as morphine in pain management of chronic, moderate to severe pain. The steady delivery and lower risk of breakthrough pain overweigh the higher cost and risk of adverse events compared to the orally delivered opioids....

  13. Visse analgetika kan med fordel anvendes transdermalt

    DEFF Research Database (Denmark)

    Jensen, Niels Martin; Holmgaard, Rikke; Nielsen, Jesper Bo

    2015-01-01

    delivered opioids have proven to be as effective as morphine in pain management of chronic, moderate to severe pain. The steady delivery and lower risk of breakthrough pain overweigh the higher cost and risk of adverse events compared to the orally delivered opioids.......Many patients experience acute or chronic pain. The options for treating these pain conditions are many, and particularly products for topical application are gaining ground. NSAID for topical use is a good alternative to NSAID administered orally due to less systemic side effects. Transdermally...

  14. Behandlingsrefraktaert status epilepticus med letal rabdomyolyse

    DEFF Research Database (Denmark)

    Kreft, Andreas; Rasmussen, Niels; Hansen, Lars Kjaersgård

    2008-01-01

    We are reporting two cases of SE with lethal rhabdomyolysis. Both were treated according to the guidelines on antiepileptic drug management by the Danish Paediatric Society, with one and two hours' delay, respectively. Intubation and midazolam infusion were needed to control seizures. After...... approximately one day both developed severe rhabdomyolysis with progressive DIC and acute renal failure, causing death despite intensive care, including acute hemodialysis. The aim of this case report is to emphasise one of the rare but severe consequences of SE and also to suggest that patients with known...

  15. Endring i adaptiv atferd hos eldre personer med utviklingshemning - en sammenligning mellom personer med Down syndrom og personer med annen utviklingshemning

    Directory of Open Access Journals (Sweden)

    Anne Marit Bygdnes

    2012-01-01

    Materiale og metode: Undersøkelsen omfatter 87 personer med utviklingshemning som tidligere har bodd på en sentralinstitusjon. Datainnsamling skjedde ved at omsorgspersoner fylte ut ABDQ.  Resultater: Det var 24 % i utvalget som hadde nedgang i adaptiv atferd. Fortolkning: ABDQ er et hjelpemiddel til å avdekke nedgang i adaptiv atferd. Det er viktig at svikt avdekkes tidligst mulig og videreformidles til helsepersonell for utredning, diagnostisering, relevant behandling og tilrettelagte helse- og omsorgstjenester. Mange personer med utviklingshemning mestrer ikke å informere om egen helsetilstand og er avhengig av at omsorgspersonalet kan avdekke sykdom og lidelser så tidlig som mulig i sykdomsforløpet.

  16. MedWatch Safety Alerts for Human Medical Products

    Data.gov (United States)

    U.S. Department of Health & Human Services — MedWatch alerts provide timely new safety information on human drugs, medical devices, vaccines and other biologics, dietary supplements, and cosmetics. The alerts...

  17. Erfaringer med Journal Club på modul 12

    DEFF Research Database (Denmark)

    Koustrup, Pia; Røge Aagaard, Lene

    2013-01-01

    I Ortopædkirurgisk afdeling, Aarhus Universitets Hospital, har vi i samarbejde med undervisere fra VIA University College udviklet og implementeret studieaktiviteten Journal Club. Studieaktiviteten afvikles indenfor rammerne af den kliniske studiemetode ”Seminar” og den planlagte studieaktivitet ...

  18. Geograf med GIS som ledetråd

    DEFF Research Database (Denmark)

    Nielsen, Søren Zebitz

    2013-01-01

    Fra speciale om kortlægning af luft forurening med NO2 i troposfæren målt fra satellit til PhD studerende med fokus på forståelsen af menneskers bevægelsesmønstre i byer. GIS og geodata er den røde tråd der binder de brede interesser indenfor geografi en sammen for denne forskerlærling.......Fra speciale om kortlægning af luft forurening med NO2 i troposfæren målt fra satellit til PhD studerende med fokus på forståelsen af menneskers bevægelsesmønstre i byer. GIS og geodata er den røde tråd der binder de brede interesser indenfor geografi en sammen for denne forskerlærling....

  19. Hvad skal vi med Etisk Råd?

    DEFF Research Database (Denmark)

    Ploug, Thomas; Gjerris, Mickey

    2012-01-01

    Det Etiske Råd har for os at se en væsentlig rolle at spille i et åbent og demokratisk samfund som det danske. Vi skal være med til at skabe grobund for de værdidiskussioner, som skal forme fremtidens samfund. Etik er at være i dialog – ikke at kaste med mudder.......Det Etiske Råd har for os at se en væsentlig rolle at spille i et åbent og demokratisk samfund som det danske. Vi skal være med til at skabe grobund for de værdidiskussioner, som skal forme fremtidens samfund. Etik er at være i dialog – ikke at kaste med mudder....

  20. Frihet & struktur : en kvalitativ studie av skolelivskvalitet hos ungdom med Tourette syndrom

    OpenAIRE

    Siverts, Torstein

    2005-01-01

    Sammendrag. Tittel: Skolelivskvalitet hos ungdom med Tourette Syndrom Med bakgrunn i egen erfaring fra arbeid med elever med Tourette Syndrom i grunnskolen, og i studier i spesialpedagogisk teori og empiri, etterstrebes det i denne studien å utvikle økt forståelse for hva slags erfaringer fra og perspektiver på sitt skoleliv elever med denne funksjonshemmende lidelsen har. Med grunnlag i analyser av intervjuer med elever om deres erfaringer og perspektiver, har jeg prøvd å b...

  1. Pragmatisk kompetanse hos barn med leppe-, kjeve-, og/ eller ganespalte

    OpenAIRE

    Vederhus, Ole-Jacob

    2015-01-01

    Denne tverrsnittstudiens hensikt er å kartlegge den pragmatiske kompetansen og de generelle kommunikasjonsferdighetene til barn med leppe-kjeve- og/ eller ganespalte. Barna (n = 17) i alderen 5:2-6:8 år ble kartlagt ved hjelp av The Children`s Communication Checklist 2 (D. V. M. Bishop, 2003), sammenlignet med sjekklistens normeringsgruppe og signifikanstestet på tvers av spaltetypene: isolert ganespalte (n = 7), leppe-, kjevespalte (n = 2) og leppe-, kjeve-, ganespalte (...

  2. Sprog hos børn med autisme

    DEFF Research Database (Denmark)

    Brynskov, Cecilia

    2010-01-01

    Spredningen i sproglige færdigheder hos børn med autisme er enorm. Dette forhold vanskeliggør forskning inden for området, og omvendt bevirker forskningen og de valg – og ikke mindst fravalg – som autismeforskere er nødt til at foretage, at gruppen af børn med autisme kommer til at fremstå mere...

  3. Forsøg med Hi-Con altanelement

    DEFF Research Database (Denmark)

    Hansen, Lars Pilegaard

    Denne rapport beskriver forsøg udført på Laboratoriet for Bærende Konstruktioner, Aalborg Universitet med et altanelement leveret af Hi-Con Aps, Hjallerup. Forsøgene er udført i september 2002. Forsøgene omfatter en statisk prøvning, hvor altanelementet blev belastet med sandsække og nedbøjningerne...

  4. Å forske med kunsten kollaborativt i en fortellerforestillingsproduksjon

    Directory of Open Access Journals (Sweden)

    Mette Bøe Lyngstad

    2018-03-01

    Full Text Available I denne artikkelen viser forskerne, som også er fortellere, hvordan de i utviklingen av sin egen fortellerforestilling forsket med kunsten. Artikkelforfatterne forsøker å vise en selvrefleksivitet og metodologisk bevissthet gjennom hele kunstproduksjonen. De undersøker hvordan en gjennom å forske med kunsten kollaborativt kan koble historiske fakta, fiksjonsfortelling og livsfortelling i en kunstproduksjon. Forskningsartikkelen tar for seg kunstproduksjonens ulike faser som brainstormfase, innsamlingsfase, fortellertekniske fase og utforskingsfase i scenerommet.

  5. Evaluering af overensstemmelsen af body condition score og feline body mass index sammenlignet med dual energy X-ray absorptiometry hos katte

    DEFF Research Database (Denmark)

    Falkenberg, Michael; Hølmkjær, Kirsten Madsen; Cronin, Anna

    2016-01-01

    Formål: Obesitet er et stigende problem blandt katte, og der er derfor brug for nemme, billige og hurtige metoder til vurdering af kattes kropssammensætning i praksis. Indeværende studie sammenligner to klinisk applicerbare metoder: Body condition score (BCS) og feline body mass index (FBMI) mod...

  6. International plastic surgery missions: a framework for resident education using the CanMEDS competencies.

    Science.gov (United States)

    White, Colin P; Lecours, Catherine; Bortoluzzi, Patricia; Caouette-Laberge, Louise; Ying, Yvonne

    2013-10-01

    Residency education has shifted over the past decade in an attempt to graduate well-rounded physicians. There is a recognition that a physician's abilities must extend beyond medical knowledge. The Royal College of Physicians and Surgeons of Canada introduced the CanMEDS physician competency framework in 2005. The framework provides 7 areas of competencies that are aimed at providing improved patient care. These competencies are medical expert, communicator, collaborator, manager, health advocate, scholar, and professional. Teaching and evaluating many of these competencies is often challenging for residency training programs. We believe that international surgical missions provide a prime opportunity to teach and evaluate all CanMEDS' roles.Plastic surgery is a field with many different organizations involved in international surgery. Many plastic surgery training programs offer opportunities for residents to become involved in these international surgical missions. Through these trips, residents gain surgical experience, see a variety and volume of clinical cases, and have the opportunity to travel to a foreign country and experience different cultures. We believe that international plastic surgery surgical missions also provide an exceptional micro environment for the teaching of CanMEDS roles. Using examples from residents' personal experiences on international plastic surgery missions to China, Mali, and Cambodia, we describe the benefits of these missions in transferring the CanMEDS competencies to resident training.

  7. Arbejdsmiljøseminarer som et redskab til at skabe motivation, ansvarlighed og ejerskab til arbejdet omkring forebyggelse af ulykker i små-, mellemstore og store virksomheder, såvel blandt ansatte som deres ledere

    DEFF Research Database (Denmark)

    Pedersen, Louise; Kines, Pete

    2009-01-01

    af arbejdsulykker. Vellykkede arbejdsmiljøseminarer kan være en metode til skabe motivation, ansvarlighed og ejerskab samt at mindske den modstand, der kan være imod forandringerne. Med andre ord at arbejde med nogle af de processer, som kan være svære at få indblik i og overskud til at arbejde med i...

  8. Inkludering av ungdom med minoritetsbakgrunn i NIF-organisert idrett

    Directory of Open Access Journals (Sweden)

    Mari Kristin Sisjord

    2014-10-01

    Full Text Available Norges Idrettsforbund og Olympiske og Paralympiske Komité (NIF har en uttalt målsetting om en åpen og inkluderende idrett. Hvordan kommer dette til uttrykk i den praktiske virksomheten? Denne artikkelen, som bygger på data fra en undersøkelse om likestilling og mangfold i den organiserte idretten (NIF, retter søkelyset mot arbeid med inklusjon av ungdom med minoritetsbakgrunn på ulike organisasjonsnivå i NIF: særforbund, idrettskretser og idrettslag. Datamaterialet er kvalitative intervju med representanter fra ulike organisasjonsnivå. Resultatene viser at NIFs overordnede politikk i varierende grad nedfelles i særforbundenes virksomhet, i idrettskretsene og i idrettslagene. Av særforbundene skiller Fotballforbundet og Klatreforbundet seg ut som aktive pådrivere i arbeidet med inkludering. Mange idrettslag oppfattet slike spørsmål som lite aktuelle i sitt rekrutteringsområde. Representanter for lag som hadde erfaring med inkludering og rekruttering av minoritetsungdom, tilkjennega varierte erfaringer og synspunkter.

  9. TwiMed: Twitter and PubMed Comparable Corpus of Drugs, Diseases, Symptoms, and Their Relations.

    Science.gov (United States)

    Alvaro, Nestor; Miyao, Yusuke; Collier, Nigel

    2017-05-03

    Work on pharmacovigilance systems using texts from PubMed and Twitter typically target at different elements and use different annotation guidelines resulting in a scenario where there is no comparable set of documents from both Twitter and PubMed annotated in the same manner. This study aimed to provide a comparable corpus of texts from PubMed and Twitter that can be used to study drug reports from these two sources of information, allowing researchers in the area of pharmacovigilance using natural language processing (NLP) to perform experiments to better understand the similarities and differences between drug reports in Twitter and PubMed. We produced a corpus comprising 1000 tweets and 1000 PubMed sentences selected using the same strategy and annotated at entity level by the same experts (pharmacists) using the same set of guidelines. The resulting corpus, annotated by two pharmacists, comprises semantically correct annotations for a set of drugs, diseases, and symptoms. This corpus contains the annotations for 3144 entities, 2749 relations, and 5003 attributes. We present a corpus that is unique in its characteristics as this is the first corpus for pharmacovigilance curated from Twitter messages and PubMed sentences using the same data selection and annotation strategies. We believe this corpus will be of particular interest for researchers willing to compare results from pharmacovigilance systems (eg, classifiers and named entity recognition systems) when using data from Twitter and from PubMed. We hope that given the comprehensive set of drug names and the annotated entities and relations, this corpus becomes a standard resource to compare results from different pharmacovigilance studies in the area of NLP. ©Nestor Alvaro, Yusuke Miyao, Nigel Collier. Originally published in JMIR Public Health and Surveillance (http://publichealth.jmir.org), 03.05.2017.

  10. Synchronously Driven Power Converter Controller Solution for MedAustron

    CERN Document Server

    Šepetavc, Luka; Tavčar, Rok; Moser, Roland; Gutleber, Johannes

    2011-01-01

    MedAustron is an ion beam cancer therapy and research centre currently under construction in Wiener Neustadt, Austria. This facility features a synchrotron particle accelerator for light ions. Cosylab is closely working together with MedAustron on the development of a power converter controller (PCC) for the 260 deployed power converters – power supplies. Power converters deliver power to magnets used for focusing and steering particle beams. We have designed and developed software and hardware which allows integration of different types of power converters into MedAustron's control system (MACS). PCC's role is to synchronously control and monitor connected power converters. Custom real-time fibre optics link and modular front end devices have been designed for this purpose. Modular front end devices make it possible to interface with almost any type of power converter – with or without built in regulation logic. We implemented realtime mechanisms and a dedicated real-time fibre link to ...

  11. Gaps in affiliation indexing in Scopus and PubMed.

    Science.gov (United States)

    Schmidt, Cynthia M; Cox, Roxanne; Fial, Alissa V; Hartman, Teresa L; Magee, Martha L

    2016-04-01

    The authors sought to determine whether unexpected gaps existed in Scopus's author affiliation indexing of publications written by the University of Nebraska Medical Center or Nebraska Medicine (UNMC/NM) authors during 2014. First, we compared Scopus affiliation identifier search results to PubMed affiliation keyword search results. Then, we searched Scopus using affiliation keywords (UNMC, etc.) and compared the results to PubMed affiliation keyword and Scopus affiliation identifier searches. We found that Scopus's records for approximately 7% of UNMC/NM authors' publications lacked appropriate UNMC/NM author affiliation identifiers, and many journals' publishers were supplying incomplete author affiliation information to PubMed. Institutions relying on Scopus to track their impact should determine whether Scopus's affiliation identifiers will, in fact, identify all articles published by their authors and investigators.

  12. Gaps in affiliation indexing in Scopus and PubMed

    Science.gov (United States)

    Schmidt, Cynthia M.; Cox, Roxanne; Fial, Alissa V.; Hartman, Teresa L.; Magee, Martha L.

    2016-01-01

    Objective The authors sought to determine whether unexpected gaps existed in Scopus's author affiliation indexing of publications written by the University of Nebraska Medical Center or Nebraska Medicine (UNMC/NM) authors during 2014. Methods First, we compared Scopus affiliation identifier search results to PubMed affiliation keyword search results. Then, we searched Scopus using affiliation keywords (UNMC, etc.) and compared the results to PubMed affiliation keyword and Scopus affiliation identifier searches. Results We found that Scopus's records for approximately 7% of UNMC/NM authors' publications lacked appropriate UNMC/NM author affiliation identifiers, and many journals' publishers were supplying incomplete author affiliation information to PubMed. Conclusions Institutions relying on Scopus to track their impact should determine whether Scopus's affiliation identifiers will, in fact, identify all articles published by their authors and investigators. PMID:27076801

  13. Den eksterne coach - neutral eller allieret med hvem?

    DEFF Research Database (Denmark)

    Müller, Marie Isolde; Elmholdt, Claus Westergård

    2015-01-01

    Denne artikel bygger på kvalitative interviews med fire eksterne professionelle coaches fra fire forskellige danske konsulentvirksomheder, der alle har coaching som en central ydelse. Salgsmaterialet på de fire virksomheders hjemmesider fortæller, at kunderne kan forvente en række positive effekter...... af samarbejdet med en ekstern professionel coach. Ved hjælp af coaching kan du opnå en bedre ledelse, bedre trivsel, større kvalitet i løsningen af kerneopgaven, mindre stress, bedre karriere, større robusthed, bedre selvværd, mere modstandsdygtighed over for forandring, større selvforståelse og...

  14. Selvforsyning med øko-mineraler og -vitaminer

    DEFF Research Database (Denmark)

    Sehested, Jakob; Jensen, Søren Krogh; Søegaard, Karen

    2010-01-01

    Forskere ved DJF har vist, at det er muligt at opnå et tilstrækkeligt indhold af vitaminer og mineraler i foderrationen til økologiske malkekøer ved at anvende hjemmedyrkede grovfodermidler med en høj andel af mineral- og vitaminrige, grønne fodermidler. Udgivelsesdato: oktober......Forskere ved DJF har vist, at det er muligt at opnå et tilstrækkeligt indhold af vitaminer og mineraler i foderrationen til økologiske malkekøer ved at anvende hjemmedyrkede grovfodermidler med en høj andel af mineral- og vitaminrige, grønne fodermidler. Udgivelsesdato: oktober...

  15. MedDigital trends and tactics to lead into the future.

    Science.gov (United States)

    Goldstein, D E; Toth, C L

    2001-01-01

    Physician executives need to harness appropriate digital technology by understanding key trends and implementing best tactics. Being and doing MedDigital means taking back control and improving care--and, at the same time, improving efficiencies and the bottom line. This article presents seven e-trends that are shaping health care: (1) Consumers and patients are pushing doctors to go digital; (2) from Web health information to MedDigital decision support; (3) beyond managed care to custom health; (4) wireless is the way of the new world; (5) Passive web portals yield to digital destinations; (6) e-commerce means lower transaction cost; and (7) develop e-health care ROI methodologies and track results. The authors provide myriad examples of new technology that will revolutionize health care and provide both physicians and consumers with valuable interactive tools to enhance health, treatment, and decision-making.

  16. Dr. med. – obsolet? Eine Querschnittserhebung zur Wahrnehmung und Akzeptanz der medizinischen Doktorarbeit

    Directory of Open Access Journals (Sweden)

    Heun, Xenia

    2014-08-01

    Full Text Available [english] Purpose: To obtain the German Medical Degree “Dr.med.” candidates are required to write a scientific thesis which is usually accomplished during Medical school education. This extra work load for the students amongst a lack of standardization and an M.D. awarded upon graduation in other European and Anglo-Saxon countries leads repeatedly to criticism of the German system. However, a systematic survey on the perception and acceptance of the German doctoral thesis among those affected is overdue.Methods: Using an online questionnaire, medical students as well as licensed doctors were asked for the status of their medical degree, their motivation, personal benefit, time and effort, scientific output, its meaningfulness and alternatives concerning their thesis. Patients were asked, how important they value their general practitioner’s title “Dr. med.”. The resulting data were evaluated performing basic statistic analyses.Results and Conclusions: The title “Dr. med.“ does not seem to be obsolete, but there is room for improvement. The scientific output is good and only a mere 15.1% of the candidates do not publish their results at all. Moreover, while at an early stage motivation, appreciation and recognition of personal benefits from the medical degree are considered as independent aspects, they merge to a general view at later stages. The current practice is considered most meaningful by the ones who have already finished their thesis. However, there are discrepancies between the expected and the actual length as well as the type of the thesis indicating that mentoring and educational advertising need improvement. As for the patients, their educational level seems to correlate with the significance attributed to the title “Dr. med.” held by their physician.

  17. Regulatory and policy barriers to effective clinical data exchange: lessons learned from MedsInfo-ED.

    Science.gov (United States)

    Gottlieb, Lawrence K; Stone, Elliot M; Stone, Diane; Dunbrack, Lynne A; Calladine, John

    2005-01-01

    MedsInfo-ED is a proof-of-concept clinical data exchange project that uses prescription claims data to deliver patient medication history to emergency department clinicians at the point of care. This patient safety initiative, while limited in scope and scale, has been crucial in identifying numerous policy and regulatory barriers to successful clinical data exchange. The lessons learned and strategies to overcome the barriers are the focus of this paper. Through commitment and effective collaboration, MA-SHARE was able to address some of these barriers that are embedded in existing government regulations and corporate business practice.

  18. Specialiserede tilbud til borgere med handicap - efter reformen

    DEFF Research Database (Denmark)

    Bonfils, Inge Storgaard; Permin Berger, Nichlas

    Som en del af kommunalreformen fik kommunerne i 2007 det fulde ansvar for handicapområdet. AKF har i 2006-2010 undersøgt, hvilke forandringer brugere, medarbejdere og ledere på specialtilbuddene oplevede i forbindelse med reformen. Undersøgelsen viser, at brugerne kun har oplevet få eller ingen æ...

  19. Senior medical students' appraisal of CanMEDS competencies.

    NARCIS (Netherlands)

    Rademakers, J.; Rooy, N. de; Cate, O.T.J. ten

    2007-01-01

    CONTEXT: In 2003 the Dutch Central College of Medical Specialties presented guidelines for the modernisation of all medical specialty training programmes in the Netherlands. These guidelines are based to a large extent on the CanMEDS (Canadian Medical Education Directives for Specialists) 2000

  20. Javnost v parkih – med opazovanjem in delovanjem. Primer Pariza

    Directory of Open Access Journals (Sweden)

    Michèle Jolé

    2008-01-01

    Full Text Available Kako naj v načrtovanje ter izgradnjo javnih parkov in vrtov vključimo tudi družbeno dimenzijo? Oziroma natančneje, kako naj uporabnikom in urbanitom določimo vlogo v projektih javnih parkov? Naša hipoteza je, da imajo družbene vede v povezavi s krajani dve vlogi – spoznavno vlogo, ki v civilni družbi opisuje rabo in družbeno dinamiko na delovnem mestu, ter vlogo posrednika (mediatorja med prebivalci in projektanti, predstavniki gradbene industrije ter vzdrževalci parkov. Obe vlogi sta med seboj tesno povezani, in sicer zaradi velike pozornosti, posvečene lokacijam. To pa zahteva empirično obravnavo. Ta je v tem članku etnografska. Metodologijo, ki jo v Parizu uporabljajo že več let, preverjamo z različnimi ameriškimi tehnikami. V članku bomo obravnavali dva primera, in sicer parka Parc Floral de Paris in Les Jardins d’Eole. Sociologijo so vsakič uporabili drugače. Modeli, ki so jih družboslovci uporabili pri obravnavanju parkov, kažejo, da bi morali razmisliti o novi »razdelitvi nalog« med različnimi udeleženci projekta, tudi med prebivalci, ki so hkrati uporabniki in državljani.

  1. One Health – Transdisziplinarität bei ZB MED

    Directory of Open Access Journals (Sweden)

    Seidlmayer, Eva

    2017-12-01

    Full Text Available By supporting disciplinary and interdisciplinary research in the fields of medicine, health care, nutritional, environmental and agricultural sciences ZB MED enables an integrated view on human health. The poster focuses on approach as well as as the underlying concepts. Additionally, the poster presents services for transdisciplinary research in the life sciences.

  2. Værkanalyse med digitale 3D modeller

    DEFF Research Database (Denmark)

    Villaume, René Domine; Ørstrup, Finn Rude

    2006-01-01

    Projektet afprøve muligheder for Værkanalyse af danske arkitekturværker med anvendelse af digitale 3D modeller. Arkitektstuderende har i en workshop udarbejdet en 3D model af Arkitekt Vilhelm Lauritzens bygning til  Københavns Lufthavn fra 1939. Modellen er herefter videreudviklet og yderligere...

  3. 9 ikke-narkotikapolitiske faktorer med beskyttende indflydelse

    DEFF Research Database (Denmark)

    Jourdan, Michael

    2007-01-01

    Sverige er verdensmester i lav prævalens. Det kan skyldes den førte narkotikapolitik. Men det kan i følge Tim Boekhut van Solinge også skyldes ikke narkotikapolitiske faktorer med beskyttende indflydelse. 9 sådanne præsenteres byggende på bogen: 'The Swedish System - an in-depth review and analysis...

  4. PubMed Central Canada: Beyond an Open Access Repository?

    Science.gov (United States)

    Nariani, Rajiv

    2013-01-01

    PubMed Central Canada (PMC Canada) represents a partnership between the Canadian Institutes of Health Research (CIHR), the National Research Council's Canada Institute for Scientific and Technical Information (NRC-CISTI), and the National Library of Medicine of the US. The present study was done to gauge faculty awareness about the CIHR Policy on…

  5. MED1 independent activation of endogenous target genes by PPARα

    DEFF Research Database (Denmark)

    Grøntved, Lars; Bugge, Anne K.; Roeder, Robert G.

    is dispensable for PPARalpha transcriptional activity in proliferating but is necessary in confluent AML-12 cells and TRAP220 KO MEFs. Collectively this indicates that the PPARs might have adopted an alternative mediator recruitment mechanism that is dispensable of direct interaction with MED1 on endogenous...

  6. Folkeretlige problemstillinger i forbindelse med konflikten mellem Ukraine og Rusland

    DEFF Research Database (Denmark)

    Buhl, Kenneth Øhlenschlæger

    Konflikten mellem Ukraine og Rusland udgør en trussel mod den internationale retsorden og dermed også hele den europæiske orden. Med henblik på at give et grundlag for at forstå omfanget af dette aspekt af konflikten behandles her lovligheden af nogle af de handlinger, som har været konfliktens...

  7. Læreren og udfordringerne med begavede og talentfulde elever

    DEFF Research Database (Denmark)

    Nissen, Poul

    2010-01-01

    Det er nu blevet stuerent at tale om de begavede og talentfulde elever i skolen. Artiklen diskuterer, hvilke elever, der kan betegnes som "talentfulde" eller med "særlige forudsætninger", og beskriver de problemer, som denne elevgruppe kan have. Samtidig påpeger forfatteren, at der mangler forskn...

  8. Hvad skete der med arbejdstiden i Folkeskolen efter Ok13?

    DEFF Research Database (Denmark)

    Hansen, Nana Wesley

    2017-01-01

    Lovindgrebet i lærerkonflikten i 2013 ændrede fundamentalt på arbejdstiden på landets Folkeskoler. Flere kommuner har dog siden indgået lokale arbejdstidsaftaler med lærerne. En ny undersøgelse fra FAOS tegner et billede af udviklingen....

  9. Sygeplejerskers MED-indflydelse på faglig kvalitet

    DEFF Research Database (Denmark)

    Ahrenkiel, Annegrethe; Dybbroe, Betina; Sommer, Finn M.

    2008-01-01

    Artiklen diskuterer, hvordan samarbejds- og medindflydelsesudvalg (MED-udvalg) fungerer i sundhedsfeltet i forhold til diskussioner af påtrængende problemer i sygeplejerskernes arbejde. Især de problemer, der drejer sig om sammenhængen mellem kvaliteten i arbejdsmiljøet og kvaliteten i arbejdet i...

  10. Frakturerede fortænder – behandling med direkte plast

    DEFF Research Database (Denmark)

    Pallesen, Ulla; van Dijken, Jan WV

    2018-01-01

    Kompositte plastmaterialer og adhæsivteknik har gjort det muligt at restaurere frakturerede fortænder med minimal risiko for pulpale og parodontale komplikationer hos både børn og voksne. Behandlingen kan udføres umiddelbart efter traumet, hvis skaden ikke involverer parodontium eller knogle. Kla...

  11. Med hjerne og hjerte - et aktionsforskningsprojekt om demensomsorg

    DEFF Research Database (Denmark)

    Hansen, Helle Krogh; Rasmussen, Else Marie

    om værdier; individuelle interviews (8 pårørende og 3 frivillige); to kernekvalitetsundersøgelser (4 medarbejdere undersøgte kvaliteter og værdier ud fra D. Ofmans teori om kernekvaliteter); en kernekvalitetsundersøgelse i samarbejde med lederen; SWOT-analyser, udarbejdelse og analyse af...

  12. Aktiv online læring med E-tiviteter

    DEFF Research Database (Denmark)

    Schneider, Maria Viftrup

    Designe e-tiviteter i vidensøgning og dertilhørende læringsobjekter. Udvikling af didaktikken ift blended learning., med anvendelse af Gilly Salmons E-tivities model som ramme for design af studieaktiviteter. Læringsprodukter hører under læringskoncepterne Undervisningsloop, Peer assessment og...

  13. Med Wise: A theory-based program to improve older adults' communication with pharmacists about their medicines.

    Science.gov (United States)

    Martin, B A; Chewning, B A; Margolis, A R; Wilson, D A; Renken, J

    2016-01-01

    -efficacy for communicating with pharmacists. At the 3 month follow-up, participants reported increased interactions with pharmacists, with 29.2% of participants reported seeking medication reviews and 28.5% medication schedule reviews. The two-class Med Wise program showed sustained impact at 3 months on key outcomes. Further, the community partners successfully implemented the program with fidelity across 8 counties suggesting its ability to be disseminated and sustained. Future directions include expanding the program to examine wider adoption, and measuring program impact on regimen safety and health outcomes linked to increases in patient engagement. Copyright © 2015 Elsevier Inc. All rights reserved.

  14. Dialysis search filters for PubMed, Ovid MEDLINE, and Embase databases.

    Science.gov (United States)

    Iansavichus, Arthur V; Haynes, R Brian; Lee, Christopher W C; Wilczynski, Nancy L; McKibbon, Ann; Shariff, Salimah Z; Blake, Peter G; Lindsay, Robert M; Garg, Amit X

    2012-10-01

    Physicians frequently search bibliographic databases, such as MEDLINE via PubMed, for best evidence for patient care. The objective of this study was to develop and test search filters to help physicians efficiently retrieve literature related to dialysis (hemodialysis or peritoneal dialysis) from all other articles indexed in PubMed, Ovid MEDLINE, and Embase. A diagnostic test assessment framework was used to develop and test robust dialysis filters. The reference standard was a manual review of the full texts of 22,992 articles from 39 journals to determine whether each article contained dialysis information. Next, 1,623,728 unique search filters were developed, and their ability to retrieve relevant articles was evaluated. The high-performance dialysis filters consisted of up to 65 search terms in combination. These terms included the words "dialy" (truncated), "uremic," "catheters," and "renal transplant wait list." These filters reached peak sensitivities of 98.6% and specificities of 98.5%. The filters' performance remained robust in an independent validation subset of articles. These empirically derived and validated high-performance search filters should enable physicians to effectively retrieve dialysis information from PubMed, Ovid MEDLINE, and Embase.

  15. MedMon: securing medical devices through wireless monitoring and anomaly detection.

    Science.gov (United States)

    Zhang, Meng; Raghunathan, Anand; Jha, Niraj K

    2013-12-01

    Rapid advances in personal healthcare systems based on implantable and wearable medical devices promise to greatly improve the quality of diagnosis and treatment for a range of medical conditions. However, the increasing programmability and wireless connectivity of medical devices also open up opportunities for malicious attackers. Unfortunately, implantable/wearable medical devices come with extreme size and power constraints, and unique usage models, making it infeasible to simply borrow conventional security solutions such as cryptography. We propose a general framework for securing medical devices based on wireless channel monitoring and anomaly detection. Our proposal is based on a medical security monitor (MedMon) that snoops on all the radio-frequency wireless communications to/from medical devices and uses multi-layered anomaly detection to identify potentially malicious transactions. Upon detection of a malicious transaction, MedMon takes appropriate response actions, which could range from passive (notifying the user) to active (jamming the packets so that they do not reach the medical device). A key benefit of MedMon is that it is applicable to existing medical devices that are in use by patients, with no hardware or software modifications to them. Consequently, it also leads to zero power overheads on these devices. We demonstrate the feasibility of our proposal by developing a prototype implementation for an insulin delivery system using off-the-shelf components (USRP software-defined radio). We evaluate its effectiveness under several attack scenarios. Our results show that MedMon can detect virtually all naive attacks and a large fraction of more sophisticated attacks, suggesting that it is an effective approach to enhancing the security of medical devices.

  16. Præstationskultur på et dansk topgymnasium: - med afsæt 3.G-elever

    OpenAIRE

    Sørensen, Christiane Færregaard; Hasselgaard, Anne Sofie Amalie Routhe; Pedersen, Jakob Valentin Stein; Usto, Sabrina; Brodersen, Kathrine Theede

    2017-01-01

    De seneste 20 år har der på mange måder været et øget konkurrence- og præstationsfokus i det danske uddannelsessystem. Dette er blandt andet kommet til udtryk i debatter om PISA tests, akademikerledighed, ny karakterskala og bonusordninger, stress og depressionsramte 12-tals piger og optagelseskrav på ungdomsuddannelser. Konstant bliver der fra politisk side italesat vigtigheden af, at danske unge til fulde udnytter deres uddannelsesmæssige potentiale, gøres omstillingsparate og konkurrencedy...

  17. Brystrekonstruktion med m. latissimus dorsi er et godt valg hos kvinder med brystkræft

    DEFF Research Database (Denmark)

    Højvig, Jens B; Bonde, Christian T

    2015-01-01

    Breast reconstruction using autologous tissue is commonly used in breast cancer patients who have received radiation therapy. The use of a latissimus dorsi flap is a safe and viable alternative to the use of an abdominal flap. The cosmetic results are excellent but there is need for a better...... understanding of the donor-site morbidity in regard to potential loss of shoulder function. We believe that it is possible to improve the procedure through optimized surgical technique in combination with the implementation and the benefits of fast-track surgery....

  18. Brystrekonstruktion med m. latissimus dorsi er et godt valg hos kvinder med brystkræft

    DEFF Research Database (Denmark)

    Højvig, Jens B; Bonde, Christian T

    2015-01-01

    Breast reconstruction using autologous tissue is commonly used in breast cancer patients who have received radiation therapy. The use of a latissimus dorsi flap is a safe and viable alternative to the use of an abdominal flap. The cosmetic results are excellent but there is need for a better unde...... understanding of the donor-site morbidity in regard to potential loss of shoulder function. We believe that it is possible to improve the procedure through optimized surgical technique in combination with the implementation and the benefits of fast-track surgery....

  19. Subjektive gener og søvnapnø blandt personer henvist til et søvncenter. En spørgeskemaundersøgelse

    DEFF Research Database (Denmark)

    Faber, C E; Grøntved, A M

    1998-01-01

    The aim of this study was to evaluate the relation between symptoms and clinical characteristics and the frequency of increased apnoea and hypopnoea activity. The study population consisted of 135 persons referred to a sleep centre. One hundred and fifteen patients (85%) completed a questionnaire...

  20. Designing, Integrating, and Coordinating the Installation of MedAustron

    CERN Document Server

    Nicquevert, B; Benedikt, M

    2011-01-01

    "Give me a layout good enough and a building to place it, and I will install your accelerator". To paraphrase Archimedes, this is the role attributed to the Integration team in the MedAustron project. Starting with the optics layout and a building sketch, the integration work consists of a series of activities, interlinked in a complex manner. First the design and the integration of accelerator: list all items, define geometrical envelopes with interfaces, put them in position in CAD, identify conflicts and define input for design of items and of infrastructure. Then the various equipment is procured: verify and validate design data, follow-up manufacturing, fiducialize equipment and build supports. Lastly the global installation: check building and infrastructure, define survey framework, install and pre-align equipment on supports, move assemblies to their final location, survey actual position and adjust to theoretical position. The whole chain of operations from the layout to a real beam in MedAustron, i...

  1. AliBaba: PubMed as a graph.

    Science.gov (United States)

    Plake, Conrad; Schiemann, Torsten; Pankalla, Marcus; Hakenberg, Jörg; Leser, Ulf

    2006-10-01

    The biomedical literature contains a wealth of information on associations between many different types of objects, such as protein-protein interactions, gene-disease associations and subcellular locations of proteins. When searching such information using conventional search engines, e.g. PubMed, users see the data only one-abstract at a time and 'hidden' in natural language text. AliBaba is an interactive tool for graphical summarization of search results. It parses the set of abstracts that fit a PubMed query and presents extracted information on biomedical objects and their relationships as a graphical network. AliBaba extracts associations between cells, diseases, drugs, proteins, species and tissues. Several filter options allow for a more focused search. Thus, researchers can grasp complex networks described in various articles at a glance. http://alibaba.informatik.hu-berlin.de/

  2. International samhandel med økologiske fødevarer

    DEFF Research Database (Denmark)

    Vestergaard, Jens; Linneberg, Mai Skjøtt

    2003-01-01

    I daglig tale opfatter man ordene økologiske fødevarer og markedet for økologiske fødevarer som dækkende en entydig kategori. Ønsker man at forstå, hvorledes den internationale samhandel med økologiske fødevarer fungerer, skal man hurtigt glemme den opfattelse. De enkelte landes eller områders øk...

  3. MED101: a laser-plasma simulation code. User guide

    International Nuclear Information System (INIS)

    Rodgers, P.A.; Rose, S.J.; Rogoyski, A.M.

    1989-12-01

    Complete details for running the 1-D laser-plasma simulation code MED101 are given including: an explanation of the input parameters, instructions for running on the Rutherford Appleton Laboratory IBM, Atlas Centre Cray X-MP and DEC VAX, and information on three new graphics packages. The code, based on the existing MEDUSA code, is capable of simulating a wide range of laser-produced plasma experiments including the calculation of X-ray laser gain. (author)

  4. BioMedBridges: External Independent Ethics Advisors Report

    OpenAIRE

    Smee, Carol

    2016-01-01

    The BioMedBridges project better enables researchers to access a wide range of data across different disciplines and allows re-analysis of datasets, some of which will have been generated through rare, expensive or unrepeatable investigations, thereby ensuring maximum utility of these datasets and facilitating new discoveries in health research. However, the sharing of data generated through the use of human material brings about ethical challenges concerning the protection of research partic...

  5. Socialpædagogik - et arbejdsfelt med paradokser

    DEFF Research Database (Denmark)

    2013-01-01

    Artiklen er en oversat og let bearbejdet udgave af professor Hans Thiersch med titlen: Sozialpädagogik - Handeln in Widersprüchen? Artiklens elementer: 1. Socialstaten som princip og socialt arbejde 2. Koncepter for det socialpædagogiske arbejde 3. Struktur og åbenhed i det socialpædagogiske...... arbejde 4. Profession og person 5. Arbejde i institutioner, indgriben 6. Perspektivering 7. Litteratur...

  6. Er genomisk selektion en revolution af avlsarbejdet med mink?

    DEFF Research Database (Denmark)

    Berg, Peer

    2011-01-01

    Genomisk selektion udnytter, at den enkelte mink kan genotypes for tusindvis af genetiske markører. Et dyrs avlsværdi kan skønnes med ret stor sikkerhed på basis af en blod- eller hårprøve, hvor dyrets sæt af genetiske markører bestemmes. Det er altså ikke nødvendigt at registrere minkens egne eg...

  7. Grønnere skibsfart med modstandsdygtige motorer

    DEFF Research Database (Denmark)

    Lassen, Lisbeth

    2015-01-01

    hastighed. Både de nye brændstoftyper og den nedsatte hastighed giver problemer for skibsmotorerne, problemer som projektet SULCOR, Sulfuric Acid corrosion in Large Marine Diesel Engines, netop har modtaget 16 millioner kr. fra Innovationsfonden til at begynde at løse. Projektet ledes af DTU Mekanik og...... foregår i samarbejde med DTU Kemiteknik og MAN Diesel & Turbo....

  8. Clinical Investigation Program RCS-MED-300(R1).

    Science.gov (United States)

    1984-09-30

    chronically at academic tasks. This condition has been associated with low self - esteem , poor self -image, depression, and academic lag. This study is...Assay for Detection ofMicroalbuminuria...................... 245 Work Unit No. 84/08 (FY84,O) Study of the Effects of Ritalin on Self Concept of...MA, Brown JM, Brown TJ: Unexpected reversal of Gallium-67 citrate avidity in an anaerobic hepatic abscess. Clin Nucl Med 9:184, 1984. Moreno AJ

  9. Interview med 11-årige børn

    DEFF Research Database (Denmark)

    Højlund, Ole; Andersen, Dines

    grænser for, hvad de kan spørges om. Og manglende læsefærdigheder kan betyde, at de fagligt svage børn glider ud af undersøgelserne. Pilotprojektet viser, at web-baserede spørgeskemaer med lyd giver mulighed for mere repræsentative undersøgelser. Undersøgelsen viser desuden, at børn godt kan svare på...

  10. Hvad skal danske hospitaler med ungecaféer?

    DEFF Research Database (Denmark)

    Kvisgaard Knudsen, Kristina; Bregnballe, Vibeke

    at forbedre unges oplevelse af at være indlagt, er der i Danmark etableret ungecaféer. Formål: At undersøge ungecaféers betydning for indlagte unge. Metode: Fire semistrukturerede interviews er foretaget med kronisk eller alvorligt syge unge i alderen 11-19 år. De unge har besøgt Café Nexus på Aarhus...

  11. Poznavanje psihogenih disfonij med logopedi in zdravstvenimi delavci

    OpenAIRE

    Krizmancic, Nikol

    2018-01-01

    Psihogene disfonije so glasovne motnje, ki izvirajo iz psihološkega neravnovesja bolnika. Uvrščamo jih med funkcionalne glasovne motnje, saj nastopijo kljub normalnemu organskemu stanju vokalnega aparata tj. odsotnosti strukturnih poškodb in/ali nevroloških motenj. Podatkov o pogostosti psihogenih glasovnih motenj v Sloveniji nimamo. Zaradi njihovega zapletenega profila in nesistematskih terapevtskih postopkov so psihogene disfonije malo in slabo raziskovane. Magistrska naloga ugotavlja po...

  12. Digital kommunikation med den offentlige sektor: Styrelser og statslige institutioner

    DEFF Research Database (Denmark)

    Berger, Jesper Bull; Andersen, Kim Normann

    digital postkasse, som borgerne kunne skrive til. I denne undersøgelse sættes der fokus på myndighedernes besvarelse af den digitale post. Digital post blev bl.a. etableret som et alternativ til almindelig e-mail for at det offentlige kan kommunikere med borgere og virksomheder på en sikker måde, dvs....... uden at uvedkommende kan få adgang til følsomme oplysninger. Fokus for undersøgelsen er hvordan håndterer myndighederne besvarelserne i den digitale postkasse: svarer de på digital post og e-mail, hvor hurtigt svarer de og er svarene brugbare? Vi har også undersøgt besvarelse af e-mail, dels...... for at kunne sammenligne de to digitale kanaler og for at kunne sammenligne med en tidligere undersøgelse af digital kommunikation med det offentlige. Herudover er der tidligere gennemført en undersøgelse af e-mail svar og svartider i New Zealand og Australien. De danske resultater fra e-mail undersøgelsen...

  13. [Systematic literature search in PubMed : A short introduction].

    Science.gov (United States)

    Blümle, A; Lagrèze, W A; Motschall, E

    2018-03-01

    In order to identify current (and relevant) evidence for a specific clinical question within the unmanageable amount of information available, solid skills in performing a systematic literature search are essential. An efficient approach is to search a biomedical database containing relevant literature citations of study reports. The best known database is MEDLINE, which is searchable for free via the PubMed interface. In this article, we explain step by step how to perform a systematic literature search via PubMed by means of an example research question in the field of ophthalmology. First, we demonstrate how to translate the clinical problem into a well-framed and searchable research question, how to identify relevant search terms and how to conduct a text word search and a search with keywords in medical subject headings (MeSH) terms. We then show how to limit the number of search results if the search yields too many irrelevant hits and how to increase the number in the case of too few citations. Finally, we summarize all essential principles that guide a literature search via PubMed.

  14. MedRapid--medical community & business intelligence system.

    Science.gov (United States)

    Finkeissen, E; Fuchs, H; Jakob, T; Wetter, T

    2002-01-01

    currently, it takes at least 6 months for researchers to communicate their results. This delay is caused (a) by partial lacks of machine support for both representation as well as communication and (b) by media breaks during the communication process. To make an integrated communication between researchers and practitioners possible, a general structure for medical content representation has been set up. The procedure for data entry and quality management has been generalized and implemented in a web-based authoring system. The MedRapid-system supports the medical experts in entering their knowledge into a database. Here, the level of detail is still below that of current medical guidelines representation. However, the symmetric structure for an area-wide medical knowledge representation is highly retrievable and thus can quickly be communicated into daily routine for the improvement of the treatment quality. In addition, other sources like journal articles and medical guidelines can be references within the MedRapid-system and thus be communicated into daily routine. The fundamental system for the representation of medical reference knowledge (from reference works/books) itself is not sufficient for the friction-less communication amongst medical staff. Rather, the process of (a) representing medical knowledge, (b) refereeing the represented knowledge, (c) communicating the represented knowledge, and (d) retrieving the represented knowledge has to be unified. MedRapid will soon support the whole process on one server system.

  15. Identifying nurse staffing research in Medline: development and testing of empirically derived search strategies with the PubMed interface.

    Science.gov (United States)

    Simon, Michael; Hausner, Elke; Klaus, Susan F; Dunton, Nancy E

    2010-08-23

    The identification of health services research in databases such as PubMed/Medline is a cumbersome task. This task becomes even more difficult if the field of interest involves the use of diverse methods and data sources, as is the case with nurse staffing research. This type of research investigates the association between nurse staffing parameters and nursing and patient outcomes. A comprehensively developed search strategy may help identify nurse staffing research in PubMed/Medline. A set of relevant references in PubMed/Medline was identified by means of three systematic reviews. This development set was used to detect candidate free-text and MeSH terms. The frequency of these terms was compared to a random sample from PubMed/Medline in order to identify terms specific to nurse staffing research, which were then used to develop a sensitive, precise and balanced search strategy. To determine their precision, the newly developed search strategies were tested against a) the pool of relevant references extracted from the systematic reviews, b) a reference set identified from an electronic journal screening, and c) a sample from PubMed/Medline. Finally, all newly developed strategies were compared to PubMed's Health Services Research Queries (PubMed's HSR Queries). The sensitivities of the newly developed search strategies were almost 100% in all of the three test sets applied; precision ranged from 6.1% to 32.0%. PubMed's HSR queries were less sensitive (83.3% to 88.2%) than the new search strategies. Only minor differences in precision were found (5.0% to 32.0%). As with other literature on health services research, nurse staffing studies are difficult to identify in PubMed/Medline. Depending on the purpose of the search, researchers can choose between high sensitivity and retrieval of a large number of references or high precision, i.e. and an increased risk of missing relevant references, respectively. More standardized terminology (e.g. by consistent use of the

  16. Både krucifikser og figurer af Jomfru Maria blev smidt ud af kirkerne ved Reformationen

    DEFF Research Database (Denmark)

    Thomassen, Bjørn; McGuire, Brian Patrick

    2016-01-01

    Interview med dronning Margrethe om blandt andet Reformationen kalder på et par supplerende kommentarer, lyder det fra en lektor og en professor i middelalderhistorie......Interview med dronning Margrethe om blandt andet Reformationen kalder på et par supplerende kommentarer, lyder det fra en lektor og en professor i middelalderhistorie...

  17. Influenza virus vaccine live intranasal--MedImmune vaccines: CAIV-T, influenza vaccine live intranasal.

    Science.gov (United States)

    2003-01-01

    that it should be able to provide these data without conducting further clinical trials. In January 2002, Aviron submitted additional clinical and manufacturing data on FluMist to the US FDA. MedImmune received a second Complete Response Letter from the US FDA on 10 July 2002, requesting clarification and additional data relating to previously submitted information. One of the most significant issues raised by the US FDA was the exacerbated rate of asthma and wheezing in 18-35-month-old patients using FluMist. MedImmune is considering two options to address this issue; to either exclude patients with asthma and wheezing from the label, or to exclude 18- to 30-month-old patients from the proposed indication. On 26 August 2002, MedImmune reported that it had completed the submission of information requested by the US FDA for FluMist. On 17 December 2002, the US FDA's Vaccination and Related Biologicals Products Advisory Committee (VRBPAC) recommended that the FDA approve FluMist to prevent influenza in healthy children, adolescents and adults (ages 5-49 years). Even though the VRBPAC voted in favour of the product's safety in the 50- to 64-year age group, they believed that the data set on efficacy for this age group was insufficient. The committee has also recommended that head-to-head studies should be conducted comparing FluMist to the marketed trivalent inactivated vaccine. Additional clinical trials suggested by the VRBPAC were shedding studies to more clearly define the probability of transmitting the influenza vaccine virus to a high-risk patient and annual revaccination studies. On 30 January 2003, MedImmune announced that it had received a Complete Response Letter from the US FDA requesting clarification and additional information relating to data previously submitted. No additional clinical trials were requested. The company responded to the five questions contained in the letter on 7 February 2003. (ABSTRACT TRUNCATED)

  18. Comparative study of MR imaging and X-ray in Med-anemia

    International Nuclear Information System (INIS)

    Huang Zhongkui; Long Liling; Song Yingru

    2002-01-01

    Objective: To evaluate the diagnostic value of MRI and X-ray and to analyze MRI and X-ray characteristics in Med-anemia. Methods: MRI was performed in thoracic spine, lumbar spine, sacral spine, pelvis, and superior femurs in 15 patients with pathologically proved Med-anemia with T 1 WI and T 2 WI. Seven of them were examined on X-ray. Twenty volunteers were examined on MR as control group. The authors analyzed the manifestations of MRI in the Med-anemia, including abnormality of signal intensity of bone marrow, T 1 value, vertebral alteration of size and shaped, spinal cord compression due to epidural extramedullary haematopoiesis, and compared with the findings of bone on X-ray. Results: In the control group, bone marrow showed an inhomogeneous iso-signal intensity with band-shaped, triangular or motley high signal intensity in the middle or back part of the vertebra, neck of the femur on T 1 WI and a homogeneous iso-signal intensity on T 2 WI in the vertebra, pelvis, and superior femur. All cases with Med-anemia had low homogenous signal intensity in the bone marrow of the vertebra, pelvis and superior femur on T 1 WI but had no alterations on T 2 WI. The spinal cord was constricted resulting from protruding crushed vertebra with bullet-like shape in 4 cases. The soft tissue masses, confirmed as extramedullary haematopoiesis by operation, were demonstrated in 4 cases. Among 7 cases with X-ray examinations, 2 cases showed normal on X-ray but abnormal bone marrow on MRI, another 5 cases demonstrated bone alteration including osteoporosis, widening of striations, enlargement of ribs and vertebras. T 1 value showed (897.4 +- 75.43) ms in the Med- anemia group and (401.5 +- 28.1) ms in the control group with significant statistical difference (P 1 WI; (2) MRI is useful in demonstrating the space occupying lesion due to vertebral deformity, enlargement of ribs and extramedullary haematopoiesis

  19. Risk of hospitalization for heart failure in patients with type 2 diabetes newly treated with DPP-4 inhibitors or other oral glucose-lowering medications: a retrospective registry study on 127,555 patients from the Nationwide OsMed Health-DB Database.

    Science.gov (United States)

    Fadini, Gian Paolo; Avogaro, Angelo; Degli Esposti, Luca; Russo, Pierluigi; Saragoni, Stefania; Buda, Stefano; Rosano, Giuseppe; Pecorelli, Sergio; Pani, Luca

    2015-09-21

    Oral glucose-lowering medications are associated with excess risk of heart failure (HF). Given the absence of comparative data among drug classes, we performed a retrospective study in 32 Health Services of 16 Italian regions accounting for a population of 18 million individuals, to assess the association between HF risk and use of sulphonylureas, DPP-4i, and glitazones. We extracted data on patients with type 2 diabetes who initiated treatment with DPP-4i, thiazolidinediones, or sulphonylureas alone or in combination with metformin during an accrual time of 2 years. The endpoint was hospitalization for HF (HHF) occurring after the first 6 months of therapy, and the observation was extended for up to 4 years. A total of 127 555 patients were included, of whom 14.3% were on DPP-4i, 72.5% on sulphonylurea, 13.2% on thiazolidinediones, with average 70.7% being on metformin as combination therapy. Patients in the three groups differed significantly for baseline characteristics: age, sex, Charlson index, concurrent medications, and previous cardiovascular events. During an average 2.6-year follow-up, after adjusting for measured confounders, use of DPP-4i was associated with a reduced risk of HHF compared with sulphonylureas [hazard ratio (HR) 0.78; 95% confidence interval (CI) 0.62-0.97; P = 0.026]. After propensity matching, the analysis was restricted to 39 465 patients, and the use of DPP-4i was still associated with a lower risk of HHF (HR 0.70; 95% CI 0.52-0.94; P = 0.018). In a very large observational study, the use of DPP-4i was associated with a reduced risk of HHF when compared with sulphonylureas. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2015. For permissions please email: journals.permissions@oup.com.

  20. Using Support Vector Machines to Detect Therapeutically Incorrect Measurements by the MiniMed CGMS®

    Science.gov (United States)

    Bondia, Jorge; Tarín, Cristina; García-Gabin, Winston; Esteve, Eduardo; Fernández-Real, José Manuel; Ricart, Wifredo; Vehí, Josep

    2008-01-01

    Background Current continuous glucose monitors have limited accuracy mainly in the low range of glucose measurements. This lack of accuracy is a limiting factor in their clinical use and in the development of the so-called artificial pancreas. The ability to detect incorrect readings provided by continuous glucose monitors from raw data and other information supplied by the monitor itself is of utmost clinical importance. In this study, support vector machines (SVMs), a powerful statistical learning technique, were used to detect therapeutically incorrect measurements made by the Medtronic MiniMed CGMS®. Methods Twenty patients were monitored for three days (first day at the hospital and two days at home) using the MiniMed CGMS. After the third day, the monitor data were downloaded to the physician's computer. During the first 12 hours, the patients stayed in the hospital, and blood samples were taken every 15 minutes for two hours after meals and every 30 minutes otherwise. Plasma glucose measurements were interpolated using a cubic method for time synchronization with simultaneous MiniMed CGMS measurements every five minutes, obtaining a total of 2281 samples. A Gaussian SVM classifier trained on the monitor's electrical signal and glucose estimation was tuned and validated using multiple runs of k-fold cross-validation. The classes considered were Clarke error grid zones A+B and C+D+E. Results After ten runs of ten-fold cross-validation, an average specificity and sensitivity of 92.74% and 75.49%, respectively, were obtained (see Figure 4). The average correct rate was 91.67%. Conclusions Overall, the SVM performed well, in spite of the somewhat low sensitivity. The classifier was able to detect the time intervals when the monitor's glucose profile could not be trusted due to incorrect measurements. As a result, hypoglycemic episodes missed by the monitor were detected. PMID:19885238

  1. Automatic identification of high impact articles in PubMed to support clinical decision making.

    Science.gov (United States)

    Bian, Jiantao; Morid, Mohammad Amin; Jonnalagadda, Siddhartha; Luo, Gang; Del Fiol, Guilherme

    2017-09-01

    The practice of evidence-based medicine involves integrating the latest best available evidence into patient care decisions. Yet, critical barriers exist for clinicians' retrieval of evidence that is relevant for a particular patient from primary sources such as randomized controlled trials and meta-analyses. To help address those barriers, we investigated machine learning algorithms that find clinical studies with high clinical impact from PubMed®. Our machine learning algorithms use a variety of features including bibliometric features (e.g., citation count), social media attention, journal impact factors, and citation metadata. The algorithms were developed and evaluated with a gold standard composed of 502 high impact clinical studies that are referenced in 11 clinical evidence-based guidelines on the treatment of various diseases. We tested the following hypotheses: (1) our high impact classifier outperforms a state-of-the-art classifier based on citation metadata and citation terms, and PubMed's® relevance sort algorithm; and (2) the performance of our high impact classifier does not decrease significantly after removing proprietary features such as citation count. The mean top 20 precision of our high impact classifier was 34% versus 11% for the state-of-the-art classifier and 4% for PubMed's® relevance sort (p=0.009); and the performance of our high impact classifier did not decrease significantly after removing proprietary features (mean top 20 precision=34% vs. 36%; p=0.085). The high impact classifier, using features such as bibliometrics, social media attention and MEDLINE® metadata, outperformed previous approaches and is a promising alternative to identifying high impact studies for clinical decision support. Copyright © 2017 Elsevier Inc. All rights reserved.

  2. Multiple roles for Med12 in vertebrate endoderm development.

    Science.gov (United States)

    Shin, Chong Hyun; Chung, Won-Suk; Hong, Sung-Kook; Ober, Elke A; Verkade, Heather; Field, Holly A; Huisken, Jan; Stainier, Didier Y R

    2008-05-15

    In zebrafish, the endoderm originates at the blastula stage from the most marginal blastomeres. Through a series of complex morphogenetic movements and differentiation events, the endodermal germ layer gives rise to the epithelial lining of the digestive tract as well as its associated organs such as the liver, pancreas, and swim bladder. How endodermal cells differentiate into distinct cell types such as hepatocytes or endocrine and exocrine pancreatic cells remains a major question. In a forward genetic screen for genes regulating endodermal organ development, we identified mutations at the shiri locus that cause defects in the development of a number of endodermal organs including the liver and pancreas. Detailed phenotypic analyses indicate that these defects are partially due to a reduction in endodermal expression of the hairy/enhancer of split-related gene, her5, at mid to late gastrulation stages. Using the Tg(0.7her5:EGFP)(ne2067) line, we show that her5 is expressed in the endodermal precursors that populate the pharyngeal region as well as the organ-forming region. We also find that knocking down her5 recapitulates some of the endodermal phenotypes of shiri mutants, further revealing the role of her5 in endoderm development. Positional cloning reveals that shiri encodes Med12, a regulatory subunit of the transcriptional Mediator complex recently associated with two human syndromes. Additional studies indicate that Med12 modulates the ability of Casanova/Sox32 to induce sox17 expression. Thus, detailed phenotypic analyses of embryos defective in a component of the Mediator complex have revealed new insights into discrete aspects of vertebrate endoderm development, and provide possible explanations for the craniofacial and digestive system defects observed in humans with mutations in MED12.

  3. Hva med de gjenstridige dokumentene? Fagreferentrollen i spesialsamlinger

    Directory of Open Access Journals (Sweden)

    Solveig Greve

    2010-07-01

    Full Text Available Spesialsamlinger er samlinger av ”gjenstridige dokumenter”, dvs. dokumenter som er sjeldne, unika eller upubliserte og derfor ofte er fysisk bundet til eierinstitusjonen. Det er typisk at slike samlinger mangler moderne standarder for metadata og felles nasjonale katalogiseringsverktøy. Eierinstitusjonene har et kulturansvar for bevaring og tilgjengeliggjøring av disse dokumentene overfor en bredere allmennhet enn et fagbiblioteks ”primærbrukere”. Fagreferentens oppgaver vil være preget av dette. Bevaring, sikring og produksjon av digitale fulltekstdokumenter er sentralt. Det er også typisk for slike samlinger at en har en betydelig backlog. Det vil være fagreferentens oppgave å løfte fram ukjent kildemateriale, gjennom digitaliseringsprosjekter og forskning. Fagreferentens viktigste oppgaver vil da være mer rettet mot samlingspleie og formidling av egne samlinger og mindre fokus på andre institusjoners samlinger. Slik vil også undervisningen av studentene bli preget av arkivpresntasjon av innhold og forelesninger om teoretiske og praktiske forhold knyttet til å arbeide med spesielle materialtyper og mindre til utvikling av vanlig informasjonskompetanse. Denne situasjonen vil forandre seg hvis/når institusjonene blir enige om utvekslingsformater og mengden av digitale fulltekstdokumenter øker. Utfordringene for spesialsamlinger vil også være fagreferentenes utfordringer; I en stadig mer elektronisk verden, kan arbeidet med de fysiske samlingene lett bli marginalisert, selv om nettopp den tekniske utviklingen kunne løse mange problemer for de gjenstridige dokumentene. Men slik prioritering krever store ressurser, høy kompetanse, engasjement og politisk gjennomslagskraft. Kostnadene er høye, og konkurrerer budsjettmessig med galopperende elektroniske utgifter for hele biblioteket. Spesialsamlingenes fagreferenter kan bli en minoritetsstemme i bibliotekenes moderniseringsprosess, til skade for bibliotekenes totale faglige

  4. Tracking Studies of the MedAustron HEBT

    CERN Document Server

    Schönauer, H

    2014-01-01

    The design of the HEBT, the High Energy Beam Transfer line of the MedAustron Hadron Therapy Centre is based on new concepts developed in the CERN PIMMS Study of the Nineties. One of those is the ‘bar-of-charge’, a very realistic description of the particularities of the horizontal phase space distribution of the slow-extracted beams. Tracking a distribution - produced by simulation of the slow extraction - from the electrostatic septum through the modules of the transfer line gives the sometimes rather particular phase space distributions and their projections at the monitors. Knowing the theoretical phase space distributions there is helpful in the interpretation of the profiles observed.

  5. Editorial announcing PubMed indexing of Oncolytic Virotherapy

    OpenAIRE

    Farassati F

    2017-01-01

    Faris Farassati1,21Saint Luke’s Cancer Institute-Saint Luke’s Marion Bloch Neuroscience Institute, Kansas City, MO, USA; 2Midwest Biomedical Research Foundation, Kansas City, MO, USAI am delighted to announce that Oncolytic Virotherapy has been accepted for indexing with PubMed. This is an exciting first step in the life of a new life sciences journal, when the scientific quality of its articles is proven high enough to meet the National Library of Medicine’s sta...

  6. Delivery of Special Magnets for the MedAustron Project

    CERN Document Server

    Kramer, T; Barlow, R A; Barnes, MJ; Borburgh, J; Ducimetière, L; Fowler, T; Hourican, M; Mertens, V; Prost, A

    2014-01-01

    Ten different types of kickers, bumpers, and electrostatic and magnetic septa, along with certain power supplies and associated control system components, have been designed in a collaboration between CERN and MedAustron for an ion therapy centre in Wr. Neustadt (Austria). This paper focuses on the status of the special magnets work package and the improvements applied during the production. The design parameters are compared with data from measurements, hardware test and initial commissioning. The major factors contributing to the successful completion of the work package are highlighted.

  7. Denmark. Alcohol, Drugs and Tobacco Programme

    DEFF Research Database (Denmark)

    Barfod, S.; Saunders, J.; Wutzke, S.

    1998-01-01

    Artiklen omtaler de danske resultater af en spørgeskemaundersøgelse blandt praktiserende læger i 16 lande. Af de 304 besvarelser angiver 91%, at de højst behandler 2 patienter om måneden for alkoholproblemer. Læger med erfaring i alkoholbehandling, og læger, der arbejder mest, spørger oftere dere...

  8. Quince años de MedUNAB

    Directory of Open Access Journals (Sweden)

    Natalia Hérnandez Rey

    2013-08-01

    Full Text Available Para conmemorar los quince años de MedUNAB el comité estudiantil quiso escribir sobre el significado que tiene para cada uno de sus miembros pertenecer a ella. Es así como en este editorial recogemos las distintas experiencias que se han tenido, algunas de años, otras de meses. MedUNAB es una escuela editorial que hace posible que tres veces al año la comunidad académica de Latinoamérica cuente, tanto física como virtualmente, con una revista científica del área de la salud. Los miembros del comité estudiantil son seleccionados por el editor y por los integrantes con más antigüedad después de hacer un entrenamiento en el cual se aprenden las bases para el proceso editorial que va desde la recepción de los artículos, hasta cómo hacer llegar la revista a cada uno de ustedes en aulas de clase, congresos, simposios, charlas y consultorios, pasando por la evaluación de los escritos, basada en los estrictos parámetros internacionales, la búsqueda de revisores calificados, la corrección de estilo y la diagramación.

  9. MedAustron - Ion-Beam Therapy and Research Center

    International Nuclear Information System (INIS)

    Schreiner, Thomas; Seemann, Rolf

    2015-01-01

    MedAustron is a synchrotron-based light-ion beam therapy center for cancer treatment as well as for clinical and non-clinical research, currently in the commissioning phase in Wiener Neustadt, Austria. Recently, the first proton beam was transported successfully to one of the four irradiation rooms. Whilst the choice of basic machine parameters was driven by medical requirements, i.e. 60 MeV protons and 120 MeV/A to 400 MeV/A carbon ions, the accelerator complex design was also optimized to offer flexibility for research operation. The potential of the synchrotron is being exploited to increase the maximum proton energy far beyond the medical needs to up to 800 MeV, for experimental physics applications, mainly in the areas of proton scattering and detector research. The accelerator layout allows for the installation of up to four ion source-spectrometer units, to provide various ion types besides the clinical used protons and carbon ions. Besides experimental physics, the two main non-clinical research disciplines are medical radiation physics and radiation biology. To decouple research and medical operation, a dedicated irradiation room for non-clinical research was included providing the installation of different experiments. In addition, several labs have been equipped with appropriate devices for preparing and analyzing radio-biological samples. This presentation gives a status overview over the whole project and highlights the non-clinical research opportunities at MedAustron. (Author)

  10. Editorial announcing PubMed indexing of Oncolytic Virotherapy

    Directory of Open Access Journals (Sweden)

    Farassati F

    2017-02-01

    Full Text Available Faris Farassati1,21Saint Luke’s Cancer Institute-Saint Luke’s Marion Bloch Neuroscience Institute, Kansas City, MO, USA; 2Midwest Biomedical Research Foundation, Kansas City, MO, USAI am delighted to announce that Oncolytic Virotherapy has been accepted for indexing with PubMed. This is an exciting first step in the life of a new life sciences journal, when the scientific quality of its articles is proven high enough to meet the National Library of Medicine’s standards for archiving. All articles published in Oncolytic Virotherapy are available through PubMed Central (as well as Dove Medical Press and are now discoverable through National Center for Biotechnology Information (NCBI suite of databases, meaning increased exposure for our authors and their research.The field of oncolytic virotherapy has moved rapidly since the 1990s when the advent of genetic engineering renewed interest in the adaptation of viruses for cancer gene therapy.1 Publications in this field reached an all-time high in 2012,2 the same year that Oncolytic Virotherapy was launched. The journal has published high-quality reviews, case reports, and original research articles across a wide range of topics. Our most viewed article is currently “Oncolytic viral therapy for pancreatic cancer: current research and future directions”,3 while the review “Oncolytic viral therapy: targeting cancer stem cells”4 has generated the most citations.

  11. Læringslandskaber for elever med indlæringsvanskeligheder

    DEFF Research Database (Denmark)

    Szulevicz, Thomas

    Baggrund Denne afhandling består af en empirisk undersøgelse af den pædagogiske praksis på Havredal Praktiske Landbrugsskole (HPL). HPL er en mesterlæreinspireret landbrugsuddannelse for unge elever mellem 16-25 år med indlæringsvanskeligheder. HPL fungerer som et moderne landbrug, der drives af...... elever og lærere i fællesskab. Der er 38 indskrevne elever på skolen, der dyrker 140 ha jord og har en besætning på 50 sortbrogede malkekøer i løsdriftsstald, 250 søer samt 10 heste. Elevernes uddannelse og læring er struktureret omkring deres deltagelse i landbrugsaktiviteterne på skolen. HPL er...... observationerne fandt sted i forskningsprojektets første 14 måneder. Herudover er der blevet foretaget kvalitative interviews med 12 elever fra HPL. Heraf blev de 7 af eleverne interviewet à 3 omgange. 7 lærere på HPL er blevet interviewet. Endelig er der blevet foretaget to videoobservationer af en elevs...

  12. MedlinePlus FAQ: MedlinePlus and MEDLINE/PubMed

    Science.gov (United States)

    ... Question: What is the difference between MedlinePlus and MEDLINE/PubMed? To use the sharing features on this ... to latest health professional articles on your topic. MEDLINE/PubMed: Is a database of professional biomedical literature ...

  13. Searching the MEDLINE literature database through PubMed: a short guide.

    Science.gov (United States)

    Motschall, Edith; Falck-Ytter, Yngve

    2005-10-01

    The Medline database from the National Library of Medicine (NLM) contains more than 12 million bibliographic citations from over 4,600 international biomedical journals. One of the interfaces for searching Medline is PubMed, provided by the NLM for free access via the Internet (www.pubmed.gov). Also searchable with the PubMed interface are non-Medline citations, i.e. articles supplied by publishers to the NLM. Direct access to an electronic full text version is also possible if the article is available from a publisher or institution participating in Linkout (www.ncbi.nlm.nih.gov/entrez/linkout/). Some publishers provide free access to their journals. Other journals require an online license and are fee based. The following example demonstrates some of the most important search functions in PubMed. We will start out with a fast and simple approach without the use of specific searching techniques and then continue with a more sophisticated search that requires the knowledge of Medline search functions. This example will show how the application of Medline search tools and how the use of the controlled vocabulary of 'Medical Subject Headings' (MeSH) will influence the results in comparison with the fast and simple approach. Let's try to find the best evidence to answer the following question: Is a 30-year-old man with typical acid reflux symptoms for many years (gastroesophageal reflux disease, GERD) more likely to develop esophageal cancer than people without reflux symptoms? This question can be split into several components: -a patient with reflux symptoms (GERD), -esophageal cancer: etiology, risk, -study design for etiology studies: cohort studies, case-control studies.

  14. Sygemeldte og førtidspensionister med handicap: Jobcentermedarbejderes perspektiver på jobcentrenes indsats

    DEFF Research Database (Denmark)

    Høgelund, Jan; Tørslev, Mette Kirstine; Weibel, Kristina

    Denne rapport belyser udvalgte jobcentermedarbejderes syn på beskæftigelsesindsatsen over for sygedagpengemodtagere og førtidspensionister med handicap. Rapporten bygger på kvalitative interviews med medarbejdere og ledelsesrepræsentanter i tre jobcentre. Der er gennemført interview med i alt 12...

  15. Forskning i musikterapi - børn med en Autisme Spektrum Forstyrrelse

    DEFF Research Database (Denmark)

    Holck, Ulla

    2011-01-01

    Der er forskningsmæssig evidens for, at musikterapi med børn med en autisme spektrum forstyrrelse (ASF) har en signifikant effekt. Cochrane reviews påviser, at musikterapi fremmer verbal og navnlig nonverbal kommunikation hos børn med ASF. En RCT-undersøgelse viser endvidere en signifikant effekt...

  16. Med5(Nut1 and Med17(Srb4 are direct targets of mediator histone H4 tail interactions.

    Directory of Open Access Journals (Sweden)

    Zhongle Liu

    Full Text Available The Mediator complex transmits activation signals from DNA bound transcription factors to the core transcription machinery. In addition to its canonical role in transcriptional activation, recent studies have demonstrated that S. cerevisiae Mediator can interact directly with nucleosomes, and their histone tails. Mutations in Mediator subunits have shown that Mediator and certain chromatin structures mutually impact each other structurally and functionally in vivo. We have taken a UV photo cross-linking approach to further delineate the molecular basis of Mediator chromatin interactions and help determine whether the impact of certain Mediator mutants on chromatin is direct. Specifically, by using histone tail peptides substituted with an amino acid analog that is a UV activatible crosslinker, we have identified specific subunits within Mediator that participate in histone tail interactions. Using Mediator purified from mutant yeast strains we have evaluated the impact of these subunits on histone tail binding. This analysis has identified the Med5 subunit of Mediator as a target for histone tail interactions and suggests that the previously observed effect of med5 mutations on telomeric heterochromatin and silencing is direct.

  17. A comparison study on the efficacy of SpinoMed® and soft lumbar orthosis for osteoporotic vertebral fracture.

    Science.gov (United States)

    Li, Meng; Law, Sheung-wai; Cheng, Jack; Kee, Ho-man; Wong, Man Sang

    2015-08-01

    Osteoporosis is one of the major health problems in aging population and may lead to osteoporotic vertebral fracture that causes severe back pain and reduced functional independency. To compare the efficacy of SpinoMed® and soft lumbar orthosis at the subacute stage (the second and third weeks of disease onset) of the patients with osteoporotic vertebral fracture. Prospective randomized trial, pilot trial. A total of 51 female subjects aged 55 years or above with osteoporotic vertebral fracture were randomly distributed to the soft lumbar orthosis (control group, n = 24) and SpinoMed® (test group, n = 27) groups after the acute stage (the first week of disease onset). The pain level was assessed by obtaining verbally feedback in 10-point scale scoring, while functional mobility level was estimated with Functional Independence Measure-motor Scores, Elderly Mobility Scale, and Modified Functional Ambulation Category. The thoracic kyphosis angle was measured from standing X-ray on 10 out of 51 subjects. Both groups showed significant reduction in the patients' pain level and limitations of daily life (p 0.05) at the subacute stage. In this study, SpinoMed® could not provide additional treatment benefits to patients with osteoporotic vertebral fracture regarding pain relief and functional independence improvement at the subacute stage. The effects of SpinoMed® in muscle-strengthening and thoracic kyphotic angle reduction for patients with osteoporotic vertebral fracture need to be further verified in a more intensive and longer-term training program. © The International Society for Prosthetics and Orthotics 2014.

  18. Personlige livsbarrierer blandt unge i Nuuk

    DEFF Research Database (Denmark)

    Jones, Sheila; Callesen, Mette Buhl; Pedersen, Michael Mulbjerg

    2017-01-01

    I forskning knyttes psykisk trivsel typisk til internaliserende problemer såsom angst, depression og ensomhed, hvorimod eksternaliserende problemer såsom manglende selvkontrol, impulsivitet og konfliktsøgende adfaerd ofte overses. Fælles for dem er dog, at disse problemer begraenser individets...

  19. Mobning som sundhedstrussel blandt store skoleelever

    DEFF Research Database (Denmark)

    Due, Pernille; Holstein, Bjørn Evald; Jørgensen, Per Schultz

    1999-01-01

    The objective was to analyse bullying in relation to sociodemographic factors, health, well-being, and health behaviours. The study is the 1998 Danish contribution to the international WHO-coordinated study Health Behaviour in School-aged Children. It includes 5,205 11-15 year-old students from...... a random sample of 55 schools who answered a standardized questionnaire. Twenty-five percent were bullied several times during the academic year, most frequently among the youngest students, and independent of sex; 32% bullied others, boys more frequently than girls; the frequency increased with age....... Bullying was associated with low social class. Bullying varied considerably among schools. The victims had more problems as regards health, well-being and self-esteem; they smoked and drank less than others. Those who bullied others also had more problems but to a much smaller extent than the victims...

  20. "Hvem er som jeg blandt Guder?"

    DEFF Research Database (Denmark)

    Holst, Søren

    2004-01-01

    En hymne fra Dødehavsrullerne beskriver en persons opstigning til himlen, hvor den pågældende får tildelt overmenneskelig indsigt, som giver ham autoritet til at belære sine tilhængere på jorden. Hymnen analyseres, og der foretages en kritisk gennemgang af Israel Knohls bog "The Messiah Before Je...