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Sample records for bk070031 idm symphony

  1. Seismic Symphonies

    Science.gov (United States)

    Strinna, Elisa; Ferrari, Graziano

    2015-04-01

    The project started in 2008 as a sound installation, a collaboration between an artist, a barrel organ builder and a seismologist. The work differs from other attempts of sound transposition of seismic records. In this case seismic frequencies are not converted automatically into the "sound of the earthquake." However, it has been studied a musical translation system that, based on the organ tonal scale, generates a totally unexpected sequence of sounds which is intended to evoke the emotions aroused by the earthquake. The symphonies proposed in the project have somewhat peculiar origins: they in fact come to life from the translation of graphic tracks into a sound track. The graphic tracks in question are made up by copies of seismograms recorded during some earthquakes that have taken place around the world. Seismograms are translated into music by a sculpture-instrument, half a seismograph and half a barrel organ. The organ plays through holes practiced on paper. Adapting the documents to the instrument score, holes have been drilled on the waves' peaks. The organ covers about three tonal scales, starting from heavy and deep sounds it reaches up to high and jarring notes. The translation of the seismic records is based on a criterion that does match the highest sounds to larger amplitudes with lower ones to minors. Translating the seismogram in the organ score, the larger the amplitude of recorded waves, the more the seismogram covers the full tonal scale played by the barrel organ and the notes arouse an intense emotional response in the listener. Elisa Strinna's Seismic Symphonies installation becomes an unprecedented tool for emotional involvement, through which can be revived the memory of the greatest disasters of over a century of seismic history of the Earth. A bridge between art and science. Seismic Symphonies is also a symbolic inversion: the instrument of the organ is most commonly used in churches, and its sounds are derived from the heavens and

  2. Other city symphonies

    OpenAIRE

    Hielscher, Eva; Jacobs, Steven

    2015-01-01

    Catalogue description of the film program curated by Eva Hielscher and Steven Jacobs on 'Other City Symphonies' during the 2015 Pordenone Silent Film Festival, including paragraphs on individual films.

  3. Tenor bass, dr02, Central Symphony

    OpenAIRE

    Helmlinger, Aurélie

    2011-01-01

    Tenor bass, dr02, augmented, Central Symphony Steel Orchestra panyard, Government House road, Tobago( erreur dans le nom de fichier : "central_symphony_steel_tenor_bass_1_dr02" ; nom correct ="central_symphony_tenor_bass_1_dr02 " )

  4. Ventilation criteria for IDMS facility

    International Nuclear Information System (INIS)

    Both Facility Evaluation Board (FEB) reviews of the Integrated DWPF Melter System (IDMS) have identified the inconsistency of the current IDMS Process Hazards Review (PHR) versus actual IDMS practice as regards the criteria to contain air borne pollutants that may be present in the Process Room (e.g. benzene and mercury). The PHR states that a 1.0 in. wc pressure differential be maintained between the IDMS Process Room and Building 672-T. In addition, the PHR further specifies that the linear velocity through openings into the Process Room (e.g. open doors) be equal to or greater than 150 fpm. Finally, the PHR recommended that mercury vapor and benzene monitors be installed in the Process Room ventilation exhaust to alert personnel to the presence of vapors of benzene and/or mercury before entering the Process Room. This report summarizes the results of reassessment of these criteria and the specific recommendation for permanent installation of mercury and benzene vapor monitors in the vapor exhaust of the Process Room

  5. A Symphony Conducted by Brunet

    CERN Document Server

    Boykin, P Oscar; Kong, Joseph S; Lozev, Kamen M; Rezaei, Behnam A; Roychowdhury, Vwani P

    2007-01-01

    We introduce BruNet, a general P2P software framework which we use to produce the first implementation of Symphony, a 1-D Kleinberg small-world architecture. Our framework is designed to easily implement and measure different P2P protocols over different transport layers such as TCP or UDP. This paper discusses our implementation of the Symphony network, which allows each node to keep $k \\le \\log N$ shortcut connections and to route to any other node with a short average delay of $O(\\frac{1}{k}\\log^2 N)$. %This provides a continuous trade-off between node degree and routing latency. We present experimental results taken from several PlanetLab deployments of size up to 1060 nodes. These succes sful deployments represent some of the largest PlanetLab deployments of P2P overlays found in the literature, and show our implementation's robustness to massive node dynamics in a WAN environment.

  6. Audiograms of symphony orchestra musicians

    DEFF Research Database (Denmark)

    Obeling, Lise; Poulsen, Torben

    1998-01-01

    1999, which takes account of the number of years at work, the number of playing hours per week, and the average sound level in the orchestra for the instrument group. In almost all cases the measured audiograms looked better than the predictions from ISO 1999.It may be concluded from this investigation...... performed during rehearsal and during concerts in the four orchestras with a sound level meter placed in various instrument groups. At the same time a noise dose meter was used to evaluate the dose perceived by specific orchestra members.The average audiogram showed a decrease at higher frequencies similar...... that musicians cannot be expected to get pronounced hearing losses from playing in a symphony orchestra. It should be noted, though, that the data material is limited, and that the subjects have not been selected in a systematical or representative way....

  7. Cylinder supplied ammonia scrubber testing in IDMS

    International Nuclear Information System (INIS)

    This report summarizes the results of the off-line testing the Integrated DWPF Melter System (IDMS) ammonia scrubbers using ammonia supplied from cylinders. Three additional tests with ammonia are planned to verify the data collected during off-line testing. Operation of the ammonia scrubber during IDMS SRAT and SME processing will be completed during the next IDMS run. The Sludge Receipt and Adjustment Tank (SRAT) and Slurry Mix Evaporator (SME) scrubbers were successful in removing ammonia from the vapor stream to achieve ammonia vapor concentrations far below the 10 ppM vapor exit design basis. In most of the tests, the ammonia concentration in the vapor exit was lower than the detection limit of the analyzers so results are generally reported as <0.05 parts per million (ppM). During SRAT scrubber testing, the ammonia concentration was no higher than 2 ppM and during SME testing the ammonia concentration was no higher than 0.05 m

  8. Hearing ability in Danish symphony orchestra musicians

    DEFF Research Database (Denmark)

    Obeling, Lise; Poulsen, Torben

    1999-01-01

    audiograms showed no signs of hearing loss. The audiograms were also compared to the expected audiograms from ISO 1999, which takes account of the number of years at work, the number of playing hours per week, and the average sound level in the orchestra for the instrument group. In almost all cases the...... equipment placed in various instrument groups. The average audiogram showed a decrease at higher frequencies similar to an age-related hearing loss. Each audiogram was corrected for the age of the person by means of the median from ISO 7029 and the average audiogram from these age-corrected individual...... measured audiograms looked better than the predictions from ISO 1999. It may be concluded from this investigation that musicians cannot be expected to get pronounced audiometric hearing losses from playing in a symphony orchestra. It should be noted, though, that the data material is limited, and that the...

  9. Efficiency of TTAC's ORTEC IDM

    Energy Technology Data Exchange (ETDEWEB)

    Livesay, Jake [ORNL; Combs, Jason C [ORNL; Margrave, Timothy E [ORNL; Miller, Ian J [ORNL

    2012-08-01

    ORNL's Technical Testing and Analysis Center (TTAC) acquired a High Purity Germanium Detector (HPGe) from ORTEC - a variant called an Interchangeable Detection Module (IDM). This detector has excellent energy resolution as well as high intrinsic efficiency. The purpose of this report is to detail the determination of the efficiency curve of the IDM, so future measurements can quantify the (otherwise unknown) activity of sources. Without such a curve, the activity cannot be directly reported by use of the IDM alone - a separate device such as an ion chamber would be required. This builds upon the capability of TTAC. The method for determining the energy-dependent intrinsic efficiency is laid-out in this report. It's noteworthy that this basic technique can be applied to any spectroscopic radiation detector, independent of the specific type (e.g. NaI, CzT, ClYC).

  10. Early event-driven (EED) RTCP feedback for rapid IDMS

    NARCIS (Netherlands)

    Montagud, M.; Boronat, F.; Stokking, H.M.

    2013-01-01

    Inter-Destination Media Synchronization (IDMS) is essential in the emerging media consumption paradigm, which is radically evolving from passive and isolated services towards dynamic and interactive group shared experiences. This paper concentrates on improving a standardized RTP/RTCP-based solution

  11. IDMS: inert dark matter model with a complex singlet

    Science.gov (United States)

    Bonilla, Cesar; Sokolowska, Dorota; Darvishi, Neda; Diaz-Cruz, J. Lorenzo; Krawczyk, Maria

    2016-06-01

    We study an extension of the inert doublet model (IDM) that includes an extra complex singlet of the scalars fields, which we call the IDMS. In this model there are three Higgs particles, among them a SM-like Higgs particle, and the lightest neutral scalar, from the inert sector, remains a viable dark matter (DM) candidate. We assume a non-zero complex vacuum expectation value for the singlet, so that the visible sector can introduce extra sources of CP violation. We construct the scalar potential of IDMS, assuming an exact Z 2 symmetry, with the new singlet being Z 2-even, as well as a softly broken U(1) symmetry, which allows a reduced number of free parameters in the potential. In this paper we explore the foundations of the model, in particular the masses and interactions of scalar particles for a few benchmark scenarios. Constraints from collider physics, in particular from the Higgs signal observed at the Large Hadron Collider with {M}h≈ 125 {{GeV}}, as well as constraints from the DM experiments, such as relic density measurements and direct detection limits, are included in the analysis. We observe significant differences with respect to the IDM in relic density values from additional annihilation channels, interference and resonance effects due to the extended Higgs sector.

  12. A symphony of data at LHCb

    CERN Multimedia

    2008-01-01

    Like musical instruments in an orchestra, the main difficulty with the many detectors of LHCb is coaxing them into playing in harmony. On 8 February 2008, for the first time, the LHCb control room team managed to extract a symphony of data from an almost complete ensemble of LHCb detectors. The LHCb control room team examining the data read out from the LHCb detectors. General view of the LHCb detector components.Now that all the detectors of LHCb are installed in the cavern they can begin to play a tune. The week of 4 February was commissioning week for the LHCb control room, when, for the first time, data from the majority of the sub-detectors (VELO, RICH 1, RICH 2, ECAL, HCAL, MUON, L0Calo and L0DU) was read out, controlled from a single window on the main computer. Sixty electronic boards, which read out the fragments of triggered events, were used during the readout at a frequency of 100 Hz. As not all of the boards ...

  13. Multimodal Biometrics and Multilayered IDM for Secure Authentication

    Science.gov (United States)

    Rashed, Abdullah; Santos, Henrique

    In the Electronic Society (e-world) users are represented by a set of data called Digital Identity (ID), which they must use for authentication purposes. Within the e-world it is certainly risky to lose the identity and this security threat must be ranking with the highest priority, forcing a solution that provides an amenable usage of digital identity. Efficient protection of the digital identity would also encourage users to enter the digital world without worries. Security needs to provide the necessary identity management (IDM) process to mitigate that threat. This paper gives an overview of IDM and suggests a framework that can be particularly useful for a secure user authentication. The proposed model appears as a multi-layered security approach, since it tries to integrate different security technologies and multimodal biometrics tools and practices, such as police, procedures, guidelines, standards and legislation. The advantages, limitations and requirements of the proposed model are discussed.

  14. Entitlement Management: Ready to Enter the IdM Mainstream

    Science.gov (United States)

    Gebel, Gerry; Wang, Alice

    Externalizing authorization processing from business applications has been a goal for architects and developers for many years. Recent compliance demands for more granular access control and policy transparency have increased the urgency to adopt an architectural model where authorization and entitlement management are consumed as a service rather than embedded within business applications. Major software vendors, such as Microsoft, Oracle, and SAP, are making significant steps to separate IdM functionality, including entitlement management from application logic. The market has also responded with a plethora of products that provide entitlement management and authorization functionality for commercial or custom-built application environments. Finally, the Extensible Access Control Markup Language (XACML) has emerged as the consensus authorization standard being supported by a growing number of IT and application vendors. Collectively, these forces form the basis of a nascent IdM market segment referred to as entitlement management.

  15. Hearing Protection and Hearing Symptoms in Danish Symphony Orchestras

    DEFF Research Database (Denmark)

    Laitinen, Heli; Poulsen, Torben

    2006-01-01

    A study about hearing protectors, problems involving hearing protector usage, hearing problems and working surroundings of classical musicians was made in three Danish symphony orchestras. The questionnaire used in the study was based on a previous study, a study made in Sweden to rock musicians,...

  16. Automated spike preparation system for Isotope Dilution Mass Spectrometry (IDMS)

    International Nuclear Information System (INIS)

    Isotope Dilution Mass Spectrometry (IDMS) is a method frequently employed to measure dissolved, irradiated nuclear materials. A known quantity of a unique isotope of the element to be measured (referred to as the ''spike'') is added to the solution containing the analyte. The resulting solution is chemically purified then analyzed by mass spectrometry. By measuring the magnitude of the response for each isotope and the response for the ''unique spike'' then relating this to the known quantity of the ''spike'', the quantity of the nuclear material can be determined. An automated spike preparation system was developed at the Savannah River Site (SRS) to dispense spikes for use in IDMS analytical methods. Prior to this development, technicians weighed each individual spike manually to achieve the accuracy required. This procedure was time-consuming and subjected the master stock solution to evaporation. The new system employs a high precision SMI Model 300 Unipump dispenser interfaced with an electronic balance and a portable Epson HX-20 notebook computer to automate spike preparation

  17. Radiation load experiments with electronic components of the SYMPHONIE satellite

    International Nuclear Information System (INIS)

    This report surveys fundamentals, realization and results of irradiation experiments which applied to 36 different electronic components of the Symphonie satellite and which were completed at the HMI Berlin and the C.N.E.T. Lannion in the years 1972/73. In a general section the evaluation of equivalent fluencies concerning 1 MeV electrons as radiation simulating the extraterrestric particle spectra with regard to the well-known semiconductor damage mechanisms is discussed. Then the realization of irradiation testing for the Symphonie satellite is described. Three selected examples demonstrate typical failure modes of semiconductor devices under radiation stress: Finally the main experimental results are shown in a standardized manner; a survey in English is given on p. 44. (orig.)

  18. Investigation of symphony orchestra musicians' use of hearing protectors

    DEFF Research Database (Denmark)

    Poulsen, Torben; Koskinen, Heli

    2010-01-01

    that musicians are aware of the dangers of loud music, that they only use hearing protectors to some extent, and that hearing protector is sometimes used only in one ear. Musicians are concerned about their hearing and musicians that experience hearing problems use hearing protectors more frequently....... At present an investigation is performed about the use of hearing aids as hearing protectors by symphony orchestra musicians. Preliminary results from this investigation will be presented at the conference....

  19. Transformational Leadership and Group Climate : empirical Results from Symphony Orchestras

    OpenAIRE

    Boerner, Sabine; Streit, Christian von

    2005-01-01

    The study investigates the degree to which the conductor s transformational leadership style and a cooperative climate in the orchestra favorably effect the orchestra s artistic quality. The authors study the assertion that the conductor s transformational leadership style promotes the orchestra s artistic quality only if there is a cooperative climate in the orchestra. An empirical study of 208 musicians from 22 professional German symphony orchestras confirms the assumed interaction effect...

  20. Symphony of colours in the Tarantula

    Science.gov (United States)

    2004-12-01

    hi-res Size hi-res: 1058 Kb Credits: ESA/NASA, ESO and Danny LaCrue Symphony of colours in the Tarantula The Tarantula is situated 170 000 light-years away in the Large Magellanic Cloud (LMC) in the southern sky and is clearly visible to the naked eye as a large milky patch. Astronomers believe that this smallish irregular galaxy is currently going through a violent period in its life. It is orbiting around the Milky Way and has had several close encounters with it. It is believed that the interaction with the Milky Way has caused an episode of energetic star formation - part of which is visible as the Tarantula Nebula. Just above the centre of the image there is a huge cluster of very hot stars called R136. The stars in R136 are also among the most massive stars we know. R136 is also a very young cluster, its oldest stars being 'just' 5 million years old or so. Its smallest stars, however, are still forming, so astronomers observe R136 to try to understand the early stages of stellar evolution. Near the lower edge of the image we find the star cluster Hodge 301. Hodge 301 is almost 10 times older than R136. Some of the stars in Hodge 301 are so old that they have already exploded as supernovae. The shockwave from this explosion has compressed the gas in the Tarantula into the filaments and sheets that are seen around the cluster. This mosaic of the Tarantula Nebula consists of images from the NASA/ESA Hubble Space Telescope’s Wide Field and Planetary Camera 2 (WFPC2) and was created by 23 year old amateur astronomer Danny LaCrue. The image was constructed by 15 individual exposures taken through three narrow-band filters allowing light from ionised oxygen (501 nm, shown as blue), hydrogen-alpha (656 nm, shown as green) and ionised sulphur (672 nm, shown as red). The exposure time for the individual WFPC2 images vary between 800 and 2800 seconds in each filter. The Hubble data have been superimposed onto images taken through matching narrow-band filters with the

  1. Astroparticle Physics - A Joint TeVPA/ IDM Conference

    CERN Document Server

    2014-01-01

    Astroparticle Physics: a joint IDM/TeVPA event brings together two major international conference series in Astroparticle Physics:Identification of Dark Matter andTeV Particle Astrophysics. We aim to provide the stage for the most recent advances in the booming field of Astroparticle Physics, bringing to Amsterdam - a city that has recently invested a lot into this research area through initiatives like GRAPPA and the D-ITP - leading members of the scientific communities that are contributing to its success. The topics of the conference will include: Cosmic Rays Dark Matter in Cosmology Direct Dark Matter Searches Indirect Dark Matter Searches High Energy Particle Physics Neutrinos High Energy Astrophysics The conference will be held at the Tuschinski Theatre, an extraordinary landmark built in 1921 in the heart of Amsterdam in a spectacular mix of Amsterdam School, Jugendstil, Art Nouveau and Art Deco. The main auditorium, which hosts many premieres of Dutch fi...

  2. Experience of determination of plutonium and uranium contents in MOX fuel by IDMS

    International Nuclear Information System (INIS)

    In the Plutonium Fuel Center (PFC) of JNC, Isotope Dilution Mass Spectrometry (IDMS) has been used to determine Pu and U contents of nuclear materials since 1996. In MOX fabrication plant, many types of sample with wide variation of Pu/U ratio including aged Pu and process scrap should be analyzed for not only quality control purpose but also material accountancy. Because IDMS can eliminate influences of coexistence elements and has high accuracy, it is considered to be the best analytical method for MOX fabrication plant. This paper summarizes the experience of IDMS in the PFC laboratory including the preparation of Large Size Dried (LSD) spike, and also describes the evaluation of analytical error and consideration on procurement of LSD spike for IDMS

  3. Design, Development and Assessment of Control Schemes for IDMS in a Standardized RTCP-based Solution

    OpenAIRE

    Montagud Climent, Mario; Boronat, Fernando; Stokking, Hans; Cesar Garcia, Pablo Santiago

    2014-01-01

    Currently, several media sharing applications that allow social interactions between distributed users are gaining momentum. In these networked scenarios, synchronized playout between the involved participants must be provided to enable truly interactive and coherent shared media experiences. This research topic is known as Inter-Destination Media Synchronization (IDMS). This paper presents the design and development of an advanced IDMS solution, which is based on extending the capabilities o...

  4. Ammonia scrubber testing during IDMS SRAT and SME processing. Revision 1

    International Nuclear Information System (INIS)

    This report summarizes results of the Integrated DWPF (Defense Waste Processing Facility) Melter System (IDMS) ammonia scrubber testing during the PX-7 run (the 7th IDMS run with a Purex type sludge). Operation of the ammonia scrubber during IDMS Sludge Receipt and Adjustment Tank (SRAT) and Slurry Mix Evaporator (SME) processing has been completed. The ammonia scrubber was successful in removing ammonia from the vapor stream to achieve NH3 concentrations far below the 10 ppM vapor exist design basis during SRAT processing. However, during SME processing, vapor NH3 concentrations as high as 450 ppM were measured exiting the scrubber. Problems during the SRAT and SME testing were vapor bypassing the scrubber and inefficient scrubbing of the ammonia at the end of the SME cycle (50% removal efficiency; 99.9% is design basis efficiency)

  5. Accurate quantification of total chromium and its speciation form Cr(VI) in water by ICP-DRC-IDMS and HPLC/ICP-DRC-IDMS.

    Science.gov (United States)

    Markiewicz, Barbara; Komorowicz, Izabela; Barałkiewicz, Danuta

    2016-05-15

    Two analytical procedures have been developed for the determination of total chromium (TCr) and its highly toxic species, i.e. Cr(VI) in water samples using the following methods: inductively coupled plasma dynamic reaction cell isotope dilution mass spectrometry (ICP-DRC-IDMS) and high performance liquid chromatography inductively coupled plasma dynamic reaction cell isotope dilution mass spectrometry (HPLC/ICP-DRC-IDMS). Spectral interferences, predominantly occurring in chromium determination, were removed using a dynamic reaction cell (DRC). The presented procedures facilitate the quantification of trace amounts - below 1 µg L(-1) of TCr and individual Cr species - in various water matrices including drinking water and still bottled water with different mineral composition. Special attention has been paid to the adequate preparation of isotopically enriched (53)Cr(VI) standard solution in order to avoid artifacts in chromium speciation. Both procedures were fully validated as well as establishing the traceability and estimation of the uncertainty of measurement were carried out. Application of all of the above mentioned elements and of the isotope dilution technique, which provides the highest quality of metrological traceability, allowed to obtain reliable and high quality results of chromium determination in water samples. Additionally, the comparison of two methods: HPLC/ICP-DRC-MS and HPLC/ICP-DRC-IDMS for Cr(VI) determination, was submitted basing on the validation parameters. As a result, the lower values for these parameters were obtained using the second method. PMID:26992546

  6. Seismic behaviour of LMFBR reactor cores. The SYMPHONY program

    International Nuclear Information System (INIS)

    As part of a comprehensive program on the seismic behaviour of the LMFBR reactor cores, the SYMPHONY experimental program, performed at the CEA Saclay, is carried out from 1993 up to now. LMFBR reactor cores are composed of fuel assemblies and neutronic shields, immersed in sodium (the primary coolant) or water (for the experimental tests). The main objective of the seismic studies is to evaluate the assembly motions, with consequences on the reactivity and the control rod insertability, and to verify the structural integrity of the assemblies under the impact forces. The experimental program has reached its objectives. Tests have been performed in a satisfying way. Instrumentation allowed to collect displacements, accelerations, and shock forces. All the results constitute a comprehensive base of valuable and reliable data. The interpretation of the tests is based on beam models, taking into account the Fluid Structure Interaction, and the shocks between the assemblies. Theoretical results are in a quite good agreement with the experimental ones. The interpretation of the hexagonal tests in water pointed out very strong coupling between the assemblies and lead to the development of a specific Fluid Structure Interaction, taking into account not only inertial effects, but dissipative effects also. (author)

  7. Dynamic behavior of the Fast Reactor cores: the Symphony program

    International Nuclear Information System (INIS)

    A fast reactor core is schematically constituted of Fuel Assemblies and Neutronic Shields, immersed in the primary coolant (sodium) which circulates inside the assemblies. Two main physical phenomena have a strong influence on the dynamic behavior of this system: the impacts between the beams and the interactions with the fluid. The impacts between the beams limit the relative displacements. The fluid leads to “inertial effects”, with globally lower vibration frequencies, and “dissipative effects”, with higher damping. Symphony is an important research program on the seismic behaviour of the fast reactor cores, developed from 1993 to 1998 at the CEA Saclay, with both experimental and theoretical parts. The experiments are at a representative scale, with Fuel Assemblies (or FA) and Neutronic Shields (or NS). Test are made “in air” (without fluid) and “in water”, to study the influence of the fluid (the sodium). A numerical model has been built for the interpretation of the tests. The interpretation of the tests is made by using a simple and efficient numerical method, based on the Euler equations for the fluid and homogenization techniques, which yields low computational costs. Impacts between the beams are taken into account also. The gaps between the feet and the grid plate lead to high damping for the beams if the gaps are important. The fluid leads to a strong coupling between the FA and the NS in the whole core, and limits the relative displacement. (author)

  8. The Pulsar Quartet: Listening to a Galactic Symphony

    Science.gov (United States)

    Kiziltan, Bülent

    2014-06-01

    Pulsars are exotic dead stars that emit very regular radio pulses. These pulses are attributed to their regular rotation. Some pulsars are spinning fast enough that the audio equivalent waveform of their pulses fall within our hearing range. If human ears were tuned to radio waves it would have been possible to ‘hear’ these very compact stars. We produced the audio waveform of these pulsar signals and mapped them onto a frequency chart to find the corresponding musical notes. We use these ‘audible' pulsars like musical instruments in a symphony orchestra to play a full quartet. At the same time, an accompanying visual interface shows the realistic distribution of all pulsars in our own Galaxy. Pulsars shine as they play each note in the quartet with realistic brightening and subsequent dimming proportional to their rotational energies. This can serve as an educational tool at all levels to demonstrate many interesting aspects of stellar evolution and articulate an aesthetic connection of us with the cosmos. Interested in watching the light show while the Milky Way Pulsar Orchestra plays a quartet?

  9. Einstein's Symphony: A Gravitational Wave Voyage Through Space and Time

    Science.gov (United States)

    Shapiro Key, Joey; Yunes, Nico; Grimberg, Irene

    2015-01-01

    Einstein's Symphony: A Gravitational Wave Voyage Through Space and Time is a gravitational wave astronomy planetarium show in production by a collaboration of scientists, filmmakers, and artisits from the Center for Gravitational Wave Astonomy (CGWA) at the University of Texas at Brownsville (UTB) and Montana State University (MSU). The project builds on the success of the interdisciplinary Celebrating Einstein collaboration. The artists and scientists who created the A Shout Across Time original film and the Black (W)hole immersive art installation for Celebrating Einstein are teaming with the Museum of the Rockies Taylor Planetarium staff and students to create a new full dome Digistar planetarium show that will be freely and widely distributed to planetaria in the US and abroad. The show uses images and animations filmed and collected for A Shout Across Time and for Black (W)hole as well as new images and animations and a new soundtrack composed and produced by the MSU School of Music to use the full capability of planetarium sound systems. The planetarium show will be narrated with ideas drawn from the Celebrating Einstein danced lecture on gravitational waves that the collaboration produced. The combination of products, resources, and team members assembled for this project allows us to create an original planetarium show for a fraction of the cost of a typical show. In addition, STEM education materials for G6-12 students and teachers will be provided to complement and support the show. This project is supported by the Texas Space Grant Consortium (TSGC), Montana Space Grant Consortium (MSGC), and the American Physical Society (APS).

  10. Sound exposures and hearing thresholds of symphony orchestra musicians.

    Science.gov (United States)

    Royster, J D; Royster, L H; Killion, M C

    1991-06-01

    To assess the risk of noise-induced hearing loss among musicians in the Chicago Symphony Orchestra, personal dosimeters set to the 3-dB exchange rate were used to obtain 68 noise exposure measurements during rehearsals and concerts. The musicians' Leq values ranged from 79-99 dB A-weighted sound pressure level [dB(A)], with a mean of 89.9 dB(A). Based on 15 h of on-the-job exposure per week, the corresponding 8-h daily Leq (excluding off-the-job practice and playing) ranged from 75-95 dB(A) with a mean of 85.5 dB(A). Mean hearing threshold levels (HTLs) for 59 musicians were better than those for an unscreened nonindustral noise-exposed population (NINEP), and only slightly worse than the 0.50 fractile data for the ISO 7029 (1984) screened presbycusis population. However, 52.5% of individual musicians showed notched audiograms consistent with noise-induced hearing damage. Violinists and violists showed significantly poorer thresholds at 3-6 kHz in the left ear than in the right ear, consistent with the left ear's greater exposure from their instruments. After HTLs were corrected for age and sex, HTLs were found to be significantly better for both ears of musicians playing bass, cello, harp, or piano and for the right ears of violinists and violists than for their left ears or for both ears of other musicians. For 32 musicians for whom both HTLs and Leq were obtained, HTLs at 3-6 kHz were found to be correlated with the Leq measured. PMID:1918623

  11. Integrated DWPF Melter System (IDMS) campaign report: The first two noble metals operations

    International Nuclear Information System (INIS)

    The Integrated DWPF Melter System (IDMS) is designed and constructed to provide an engineering-scale representation of the DWPF melter and its associated feed preparation and off-gas systems. The facility is the first pilot-scale melter system capable of processing mercury, and flowsheet levels of halides and noble metals. In order to characterize the processing of noble metals (Pd, Rh, Ru, and Ag) on a large scale, the IDMS will be operated batchstyle for at least nine feed preparation cycles. The first two of these operations are complete. The major observation to date occurred during the second run when significant amounts of hydrogen were evolved during the feed preparation cycle. The runs were conducted between June 7, 1990 and March 8, 1991. This time period included nearly six months of ''fix-up'' time when forced air purges were installed on the SRAT MFT and other feed preparation vessels to allow continued noble metals experimentation

  12. IDM as a "Minor" Literature: The Treatment of Cultural and Musical Norms by "Intelligent Dance Music"

    Directory of Open Access Journals (Sweden)

    Ramzy Alwakeel

    2009-09-01

    Full Text Available This piece opens with a consideration of the etymology and application of the term “IDM”, before examining the treatment of normative standards by the work associated therewith. Three areas in particular will be focused upon: identity, tradition, and morphology. The discussion will be illuminated by three case studies, the first of which will consider Warp Records’ relationship to narrative; the two remaining will explore the work of Autechre and Aphex Twin with some reference to the areas outlined above. The writing of Deleuze and Guattari will inform the ideas presented, with particular focus being made upon the notions of “minority”, “deterritorialisation”, and “continuous variation”. Based upon the interaction of the wider IDM “text” with existing “constants”, and its treatment of itself, the present work will conclude with the suggestion that IDM be read as a “minor” literature.

  13. A combination of gas chromatography, combustion, and 13C/12C isotope dilution mass spectrometry (GC/C/IDMS)

    International Nuclear Information System (INIS)

    Isotope dilution mass spectrometry (IDMS) is a method of amount-of-substance measurement which offers the capabilities of a primary method. This method provides results of low uncertainty which are traceable to the SI units. It is therefore suitable for ambitious amount-of-substance measurements. It can be expected from the results of a model analysis presented here that the new GC/C/IDMS method of organic analysis is capable of providing measurement results with a higher accuracy that has been possible up to now

  14. Integrated DWPF Melter System (IDMS) campaign report: Hanford Waste Vitrification Plan (HWVP) process demonstration

    Energy Technology Data Exchange (ETDEWEB)

    Hutson, N.D.

    1992-08-10

    Vitrification facilities are being developed worldwide to convert high-level nuclear waste to a durable glass form for permanent disposal. Facilities in the United States include the Department of Energy`s Defense Waste Processing Facility (DWPF) at the Savannah River Site, the Hanford Waste Vitrification Plant (HWVP) at the Hanford Site and the West Valley Demonstration Project (WVDP) at West Valley, NY. At each of these sites, highly radioactive defense waste will be vitrified to a stable borosilicate glass. The DWPF and WVDP are near physical completion while the HWVP is in the design phase. The Integrated DWPF Melter System (IDMS) is a vitrification test facility at the Savannah River Technology Center (SRTC). It was designed and constructed to provide an engineering-scale representation of the DWPF melter and its associated feed preparation and off-gas treatment systems. Because of the similarities of the DWPF and HWVP processes, the IDMS facility has also been used to characterize the processing behavior of a reference NCAW simulant. The demonstration was undertaken specifically to determine material balances, to characterize the evolution of offgas products (especially hydrogen), to determine the effects of noble metals, and to obtain general HWVP design data. The campaign was conducted from November, 1991 to February, 1992.

  15. Integrated DWPF Melter System (IDMS) campaign report: Hanford Waste Vitrification Plan (HWVP) process demonstration

    International Nuclear Information System (INIS)

    Vitrification facilities are being developed worldwide to convert high-level nuclear waste to a durable glass form for permanent disposal. Facilities in the United States include the Department of Energy's Defense Waste Processing Facility (DWPF) at the Savannah River Site, the Hanford Waste Vitrification Plant (HWVP) at the Hanford Site and the West Valley Demonstration Project (WVDP) at West Valley, NY. At each of these sites, highly radioactive defense waste will be vitrified to a stable borosilicate glass. The DWPF and WVDP are near physical completion while the HWVP is in the design phase. The Integrated DWPF Melter System (IDMS) is a vitrification test facility at the Savannah River Technology Center (SRTC). It was designed and constructed to provide an engineering-scale representation of the DWPF melter and its associated feed preparation and off-gas treatment systems. Because of the similarities of the DWPF and HWVP processes, the IDMS facility has also been used to characterize the processing behavior of a reference NCAW simulant. The demonstration was undertaken specifically to determine material balances, to characterize the evolution of offgas products (especially hydrogen), to determine the effects of noble metals, and to obtain general HWVP design data. The campaign was conducted from November, 1991 to February, 1992

  16. A framework for using optical sensors in nanomeasuring machines over I++/DME

    International Nuclear Information System (INIS)

    This paper discusses the problem of integrating optical sensors into CMMs. First the basic concept of optical sensors is briefly introduced as well as the targeted measurement implementation standard, I++DME, and the Optical Sensor Interface Standard, which is still seldom used but is gaining acceptance. A novel generic software framework is introduced which helps to simplify the use of optical sensors in CMMs. To demonstrate the feasibility of integrating an optical sensor into a CMM, the framework has been successfully implemented around a white light interferometer, in which the sensor system is mounted in an ultra-precision CMM. The actual process control and data analysis was done using a third-party metrology application, which does not normally support either ultra-precision CMMs or optical sensors. (paper)

  17. IDMS studies on sodalite - a candidate material for nuclear waste containment

    International Nuclear Information System (INIS)

    Nuclear waste management is one of the important aspects of nuclear fuel cycle from environmental and safety considerations. Different forms of waste storage matrices are known to be applicable for different kinds of nuclear wastes. Glass bonded sodalite (GBS) (Na8(AISiO4)6Cl2), a glass-ceramic, is a promising candidate for the immobilization of the chloride waste resulting from pyrometallurgical reprocessing of nuclear fuels. Characterization of individual components is essential for the development of this waste storage material which is expected to encounter different physicochemical conditions. For this purpose, we have undertaken studies to determine the concentrations of individual components in GBS employing Isotope Dilution Mass Spectrometry (IDMS) owing to its capability to ensure precise and accurate data for multi element analysis in a matrix

  18. Innovation and Selection: Symphony Orchestras and the Construction of the Musical Canon in the United States (1879-1959)

    Science.gov (United States)

    Kremp, Pierre-Antoine

    2010-01-01

    This article analyzes the determinants of innovation and success of innovation in the field of U.S. symphony orchestras from 1879 through 1959: why did major orchestras (N = 27) innovate by introducing works of new composers to the repertoire instead of sticking to canonical pieces? Can organizational processes account for the selection and the…

  19. Computer Simulation Tests of Feedback Error Learning Controller with IDM and ISM for Functional Electrical Stimulation in Wrist Joint Control

    Directory of Open Access Journals (Sweden)

    Takashi Watanabe

    2010-01-01

    Full Text Available Feedforward controller would be useful for hybrid Functional Electrical Stimulation (FES system using powered orthotic devices. In this paper, Feedback Error Learning (FEL controller for FES (FEL-FES controller was examined using an inverse statics model (ISM with an inverse dynamics model (IDM to realize a feedforward FES controller. For FES application, the ISM was tested in learning off line using training data obtained by PID control of very slow movements. Computer simulation tests in controlling wrist joint movements showed that the ISM performed properly in positioning task and that IDM learning was improved by using the ISM showing increase of output power ratio of the feedforward controller. The simple ISM learning method and the FEL-FES controller using the ISM would be useful in controlling the musculoskeletal system that has nonlinear characteristics to electrical stimulation and therefore is expected to be useful in applying to hybrid FES system using powered orthotic device.

  20. Expression Surpassing Words: Gorecki’s Symphony No. 3, Op. 36 “Sorrowful Songs”

    Directory of Open Access Journals (Sweden)

    Alyssa K. Griffith

    2015-12-01

    Full Text Available The experience of listening to Gorecki’s Symphony no. 3, op. 36 “Sorrowful Songs” is one that is not easily forgotten. It is not only musically captivating, but also historically fascinating. After its premiere in 1977, Gorecki’s piece captivated listeners across the globe as it became a cultural phenomenon in both Europe and America. The music was a stunning success in both the Classical and popular cultures. What is it about the music that is so captivating? How did the trending, popular thoughts compare to Gorecki’s original ideas and compositional motives? What actually inspired this piece? By looking at the composition and premise of each movement, I am going to introduce how the piece was written around the theme of maternal love and separation of mother and child. The Third Symphony was heavily influenced by Gorecki’s personal past, but also by his Catholic beliefs and by Polish history. The separate texts to this three movement piece deal individually with a mother’s lament over her son’s departure, the Virgin Mary’s grief at her Son’s death, and finally the words of an incarcerated prison girl to her mother. Because of the setting from which the third text was drawn, and because of Gorecki’s Polish history and experiences in the post-holocaust world, many people have interpreted this to be a “war piece” which avenges the sufferers of the Holocaust. According to Gorecki, this piece is a lament- it expresses a profound sense of grief which, arguably, cannot accurately be expressed with words. Gorecki used his music to confront, mourn, and express his pain and the pain of many other people. By finding primary sources, such as interviews of Henryk Gorecki, and by looking at the scholarly books and journals by Luke B. Howard, Adrian Thomas, and other scholars of Polish avant-garde music, I hope to properly understand and express the intentions Gorecki wished to convey by writing The Symphony of Sorrowful Songs.

  1. Transfinite harmonization by taking the dissonance out of the quantum field symphony

    International Nuclear Information System (INIS)

    Particle physics may be likened to a magnificent symphony. Alas due to some instrumental defects, wrong reading of the notes and a lack of virtuosity of some members of the orchestra, a non-negligible number of dissonants are making it sound less than perfect. By means of the specific example of renormalization groups applied to GUT unification, the present work aims at illustrating the point we just made and showing how a simplictic transfinite adjustment of our formulas lead to harmonization and consequently considerable simplification of well known theories which goes as far as facilitating the discovery of new connections and the solution of many problems which were previously thought very hard, if at all possible, to solve

  2. Large size dry (LSD) spike isotope dilution mass spectrometry (IDMS) for input accounting of U and Pu in fuel reprocessing : a field experience

    International Nuclear Information System (INIS)

    State of the art analytical measurement instruments are used for nuclear material accounting. In the ever continuing process of strengthening the safeguards and related mechanism, the onus has now shifted towards improving the agreement between the nuclear material measurements performed by facility lab. and SAL, IAEA. A first step has been taken in this direction by SAL, IAEA in suggesting use of common (for facility and reference lab.) LSD mixed (U,Pu) spike for IDMS determination of U, Pu in input KMP tanks of spent fuel reprocessing plants. An exercise was carried out to field test the feasibility of LSD-IDMS procedure

  3. Einstein's unfinished symphony listening to the sounds of space-time

    CERN Document Server

    Bartusiak, Marcia

    2000-01-01

    A new generation of observatories, now being completed worldwide, will give astronomers not just a new window on the cosmos but a whole new sense with which to explore and experience the heavens above us. Instead of collecting light waves or radio waves, these novel instruments will allow astronomers to at last place their hands upon the fabric of space-time and feel the very rhythms of the universe. These vibrations in space-time-or gravity waves-are the last prediction of Einstein's general theory of relativity yet to be observed directly. They are his unfinished symphony, waiting nearly a century to be heard. When they finally reveal themselves to astronomers, we will for the first time be able to hear the cymbal crashes from exploding stars, tune in to the periodic drumbeats from swiftly rotating pulsars, listen to the extended chirps from the merger of two black holes, and eavesdrop on the remnant echoes from the mighty jolt of the Big Bang itself. When Einstein introduced general relativity in 1915, it ...

  4. The combined positive impact of Lean methodology and Ventana Symphony autostainer on histology lab workflow

    Directory of Open Access Journals (Sweden)

    Glass Crystal F

    2010-02-01

    Full Text Available Abstract Background Histologic samples all funnel through the H&E microtomy staining area. Here manual processes intersect with semi-automated processes creating a bottleneck. We compare alternate work processes in anatomic pathology primarily in the H&E staining work cell. Methods We established a baseline measure of H&E process impact on personnel, information management and sample flow from historical workload and production data and direct observation. We compared this to performance after implementing initial Lean process modifications, including workstation reorganization, equipment relocation and workflow levelling, and the Ventana Symphony stainer to assess the impact on productivity in the H&E staining work cell. Results Average time from gross station to assembled case decreased by 2.9 hours (12%. Total process turnaround time (TAT exclusive of processor schedule changes decreased 48 minutes/case (4%. Mean quarterly productivity increased 8.5% with the new methods. Process redesign reduced the number of manual steps from 219 to 182, a 17% reduction. Specimen travel distance was reduced from 773 ft/case to 395 ft/case (49% overall, and from 92 to 53 ft/case in the H&E cell (42% improvement. Conclusions Implementation of Lean methods in the H&E work cell of histology can result in improved productivity, improved through-put and case availability parameters including TAT.

  5. Investigation and experimental validation of the contribution of optical interconnects in the SYMPHONIE massively parallel computer

    International Nuclear Information System (INIS)

    Progress in microelectronics lead to electronic circuits which are increasingly integrated, with an operating frequency and an inputs/outputs count larger than the ones supported by printed circuit board and back-plane technologies. As a result, distributed systems with several boards cannot fully exploit the performance of integrated circuits. In synchronous parallel computers, the situation is worsen since the overall system performances rely on the efficiency of electrical interconnects between the integrated circuits which include the processing elements (PE). The study of a real parallel computer named SYMPHONIE shows for instance that the system operating frequency is far smaller than the capabilities of the microelectronics technology used for the PE implementation. Optical interconnections may cancel these limitations by providing more efficient connections between the PE. Especially, free-space optical interconnections based on vertical-cavity surface-emitting lasers (VCSEL), micro-lens and PIN photodiodes are compatible with the required features of the PE communications. Zero bias modulation of VCSEL with CMOS-compatible digital signals is studied and experimentally demonstrated. A model of the propagation of truncated gaussian beams through micro-lenses is developed. It is then used to optimise the geometry of the detection areas. A dedicated mechanical system is also proposed and implemented for integrating free-space optical interconnects in a standard electronic environment, representative of the one of parallel computer systems. A specially designed demonstrator provides the experimental validation of the above physical concepts. (author)

  6. Determination of heavy metals (Pd, Cd, Cu, Zn, Cr) in sedimentary reference materials with IDMS: Total concentration and aqua regia soluble portion

    Energy Technology Data Exchange (ETDEWEB)

    Goetz, A.; Heumann, K.G.

    1988-12-01

    The total concentration and the aqua regia soluble portion of traces of Pb, Cd, Cu, Zn, and Cr are determined with isotope dilution mass spectrometry (IDMS) in three different types of sediments using a thermal quadrupole instrument (THQ). The results are compared with those obtained by other methods during a certification project to establish these sediments (BCR 277, BCR 280, BCR 320) as standard reference materials. The IDMS (THQ) results are in good agreement with the preliminary certification values and the results of two other laboratories, which applied IDMS using magnetic sector field mass spectrometers. Significant differences between the different analytical methods were found for the total Pb concentration, which could be explained by adsorption and coprecipitation effects during the chemical pretreatment of samples. Using aqua regia instead of HF/HNO/sub 3/ for the decomposition of sediments, only 65%-95% of the total Pb and 60%-90% of the total Cr could be dissolved. On the other hand, only a small or negligible portion of Zn, Cd, and Cu could not be dissolved by aqua regia. The IDMS values for the aqua regia soluble Cr portion are significantly higher compared to the results of other methods. This can be explained by adsorption effects.

  7. New age in Serbia, Zoran Simjanović: New ideas symphony

    Directory of Open Access Journals (Sweden)

    Radović Branka

    2007-01-01

    Full Text Available ′New age′ was a trend which appeared in the music of the 1980’s, bringing a new dimension to art music in general, especially in its reception. At first its development was stimulated by technological inventions, ′the technological craze′, by new carriers of sound, simultaneously globalizing art and making it widely accessible. This new trend includes quite disparate categories. It does not distance itself from subculture, and in art music it gravitates towards cosmopolitism while being permeated with other musical trends such as pop, rock, jazz and other phenomena of show business and popular art. This trend was originally found in the large number of occult writing which flooded book markets all over the world, to which Umberto Eco gave an important base (Foucault's Pendulum and others. In his essay on the music of the eighties, Peter Niklas Wilson, one of the most significant theoreticians of this movement, researches into all elements of those novelties, not hesitating to call this art eclectic, commercial and the like. Examples of Serbian music get into such style directives. The New Ideas Symphony by film score composer Zoran Simjanović, was performed in the open air at Kalemegdan fortress in 2006, before an audience of about one thousand people. Since then the recording has often been broadcast on television and radio channels. In its combination of folklore and film models, traces of rock, pop, and jazz can also be found, in a score with all symphonic characteristics. This attempt is a fascinating item for research as well as a pleasure to be listened to.

  8. Ergonomic activity analysis of the musicians of the Symphony Orchestra of Paraná state: risk factors and workloads

    Directory of Open Access Journals (Sweden)

    Jaqueline de Lima

    2014-04-01

    Full Text Available This study aimed to investigate the risk factors present in the work activity and their impact on the health of the musicians of the Symphony Orchestra of Parana state. It is a descriptive qualitative research based on the method of Ergonomic Workplace Analysis of Francophone strand, used as a tool by occupational therapists in the health-work interface. The following procedures were performed: bibliographical survey, documental analysis of productivity data, production and quality of the task, systematic observation of the rehearsals of the Symphony Orchestra of Parana, task and workplace analysis with the application of Ergonomic Workplace Analysis (EWA and, confrontation of the data analyzed with an instrumental musician. As a result, the study showed significant deviations with reference to the standards described in Brazilian Norm 17 (Ergonomics, especially regarding individual cognitive and physical demands as well as demands related to work organization, considering each item evaluated by this analytical instrument. The action of occupational therapy was grounded on the insertion in the health and illness process, health promotion, illness prevention, and training of musicians as workers and social actors, envisioning the transformation of work situations.

  9. Prevalence and consequences of musculoskeletal symptoms in symphony orchestra musicians vary by gender: a cross-sectional study

    DEFF Research Database (Denmark)

    Paarup, Helene M.; Baelum, Jesper; Holm, Jonas W;

    2011-01-01

    , while physiotherapists and general practitioners were reported as the most consulted health care professionals concerning musculoskeletal problems. Results regarding symptoms in six anatomic regions were compared to results for a sample of the general Danish workforce. Symptoms were more frequent in...... musicians and lasted longer than in the general workforce. This applied to both genders. CONCLUSIONS: Within the last year most symphony orchestra musicians experienced musculoskeletal symptoms in the neck, back or upper extremities. The symptoms impacted on their level of function in and outside work and...... were reflected in their health behaviour. Generally women had a higher risk than men and woodwind players a lower risk than other instrumentalists. Finally, symptoms were more frequent and lasted longer in the musicians than in the general workforce....

  10. Is the Unspeakable Singable? The Ethics of Holocaust Representation and the Reception of Górecki's Symphony no.3

    Directory of Open Access Journals (Sweden)

    Alison Moore

    2011-08-01

    Full Text Available Debates about Holocaust representation have long been haunted by the idea that the enormity and intensity of human suffering in the events of World War Two are ‘unspeakable’. In many such statements the capacity for cognition and the ethical dimension of aestheticisation are blurred – the Holocaust is ‘unspeakable’ both in the sense of being impossible to imagine in its full horror, but also morally inappropriate as the subject of artistic production. But do all forms of cultural representation of the Holocaust fail in the same way as words or to the same degree, in the eyes of those who would judge their merits according the tenet of unspeakability? This paper considers one particularly renowned work Henryk Górecki’s symphony no. 3 (Symfonia pieśni żałosnych of 1976, discussing how it mediated both the global politics of Holocaust representation and the recuperation of victimhood in postcommunist Poland. Górecki claimed a subjectivity of failure in response to the challenge of representing the events of World War Two and has insisted that the symphony is not about war but about sorrow. The vocal lyrics are nonetheless profoundly thematised around war suffering, and the Second World War in particular - events he approached with a musical language of epic, pathos and redemption. In framing the subject of his work, he emphasised a Polish national suffering that both eschewed mention of specifically targeted groups of victims, and beckoned to Polish folk and catholic traditions. This article presents a new hypothesis about the success of Górecki’s work by considering it in relation to the ethical debates about Holocaust empathic response that have occurred in relation to historiographic, literary and filmic representation.

  11. Full method validation for the determination of hexachlorobenzene and hexachlorobutadiene in fish tissue by GC-IDMS.

    Science.gov (United States)

    Majoros, Laszlo I; Lava, Roberto; Ricci, Marina; Binici, Burcu; Sandor, Florian; Held, Andrea; Emons, Hendrik

    2013-11-15

    This paper summarizes the validation strategy and the results obtained for the simultaneous determination of hexachlorobenzene (HCB) and hexachlorobutadiene (HCBD) in fish tissue with a maximum of about 10% m/m fat content using a GC-IDMS technique. The method is applicable for the determination of HCB and HCBD at trace levels in different kinds of fish tissue samples in accordance with the requirements of the EU Directive 2008/105/EC establishing Environmental Quality Standard (EQS) levels for biota in aquatic ecosystems (10 ng/g for HCB and 55 ng/g for HCBD). The method validation aimed to assess performance parameters such as linearity, limit of detection/limit of quantification (LOD/LOQ), trueness, selectivity, intermediate precision, repeatability, stability of the extracts and robustness. The validation experiments have been performed by using uncontaminated fish tissue. Trueness was evaluated by using a certified reference material (NIST SRM 1947) (where applicable) and by the standard addition method. Very good linear signal-concentration curves were obtained for both analytes over the whole range of calibration. The repeatability and the intermediate precision of the method, expressed as relative standard deviation (RSD) and calculated at the EQS level, were estimated to be below 3% both for HCB and HCBD. The limits of quantification were 3.7 ng/g for HCB and 15.7 ng/g for HCBD in the fish. An uncertainty budget for the measurement of both HCB and HCBD in fish at about the EQS levels, applying the described method, has been established in the order of 10%. The analytical method and its performance characteristics take into account the requirements of EU Directive 2009/90/EC regarding the establishment of minimum performance criteria for the methods of analysis to be used in the water monitoring activity of the Water Framework Directive. Finally, the validated method was successfully tested on contaminated Silurus glanis from Ebro River (Spain). The method

  12. Influences de la symphonie concertante sur la musique de la Cour parisienne sous l'Empire et la Restauration (1800-1830

    Directory of Open Access Journals (Sweden)

    Dratwicki, Alexandre

    2003-12-01

    Full Text Available The origins of the very much appreciated "symphonie concertante" can be found in the importance of public concerts given in Paris at the end of the 18th century. The specific repertoire played at the French Court during the years 1800-1830 distinctly shows this vogue for the "symphonie concertante", for it reveals the still unknown importance of virtuosity. Considered as an musical entertainment for the pompous parties at the French Court or as an musical accompaniment for the masses given at the Imperial and Royal Chapel, this "decorative concertant syle" became an essential part of the Regime etiquette during the Napoleonic empire as well as the Restoration period. This music, perfectly incorporated into the official guidelines, will disappear as a consequence of the political events of 1830 and the arrival of a new aesthetic movement, the Romanticism.

    [fr] La vogue du concert public à Paris, à la fin du XVIIIe siècle, fut à l'origine de l'essor phénoménal que connut la symphonie concertante. Le répertoire de la musique de la Cour - entre 1800 et 1830 - est particulièrement représentatif de cette mode : il révèle une place encore insoupçonnée laissée à la virtuosité. Agrémentant les messes de la Chapelle ou les bals donnés lors de fastueuses soirées, ce « style concertant décoratif » devint un élément constitutif de l'apparat gouvernemental sous l'Empire et la Restauration. Une sorte d'académisme officiel que les événements politiques de 1830 et l'essor du romantisme musical feront définitivement disparaître.

  13. Life's Ethical Symphony

    Science.gov (United States)

    Mendus, Susan

    2008-01-01

    Most modern moral theories are impartialist in character. They perceive the demands of morality as standing in opposition to partial concerns and acting as constraints upon them. In this paper I argue that our partial concerns in general, and our love and concern for others in particular, are not ultimately at odds with the demands of morality,…

  14. Symphony no. Alcuin's Riddle.

    Science.gov (United States)

    Veeneman, Curt H.

    Alcuin, an eighth century poet, mathematician, educator and cleric, was the foremost scholar of the Carolingian Renaissance. Indeed, he was Charlemagne's antidote to illiteracy in the middle ages. He also loved riddles. One of his riddles, a, favorite of mine, presents a ferrying problem: A man has a wolf, a goat, and a bundle of cabbages. He must cross a river, but his boat is so small that he can take only one of them at a time. For obvious reasons, he cannot leave the goat with the cabbages, nor the wolf with the goat. The question is how many crossings must he make. The solution to this riddle suggested an intriguing form to me: one that is not only rounded, but has palindromic characteristics. The concept of a time-space relationship informs the large-scale design of this work. I have made the audience the "river," allowing them to hear the solution to the riddle unfold--in the midst of the action. (And once an audience member solves the riddle he will have a sense of when the music will end!) The work is scored for an orchestra on stage and 15 soloists in the audience, who span the auditorium from the stage to the rear, and function as a medium by which the music crosses the audience-river.

  15. Symphony orchestra musicians′ use of hearing protection and attenuation of custom-made hearing protectors as measured with two different real-ear attenuation at threshold methods

    Directory of Open Access Journals (Sweden)

    K H Huttunen

    2011-01-01

    Full Text Available Despite a high level of sound exposure and a fairly large selection of earplugs available, musicians have often been reported to use personal hearing protectors only seldom. For better hearing conservation, it is important to identify and eliminate the causes for the low motivation to use hearing protection. We explored the usage rate of custom-molded musician′s earplugs (ER-15 among 15 symphony orchestra musicians with a questionnaire, and measured the attenuation properties of their earplugs with a Real-Ear Attenuation at Threshold (REAT procedure in a sound field. Earplug use was found to be low, and the musicians reported that earplugs hampered listening to their own and their colleagues′ playing; earplugs affected either timbre or dynamics, or both. Additionally, several reasons related to discomfort of use were itemized, but the musicians who consistently used their earplugs did so in spite of problems with use. The REAT values obtained in sound field were relatively close to the manufacturer′s nominal specifications, being 13.7 dB, on average. In the frequency range studied (0.125-8 kHz, individual variation in REAT was, however, up to 15 dB across the measured frequencies. Fluctuation in attenuation might be related to low use of hearing protectors, and REAT measured at fixed center frequencies may be too robust a method to uncover it. We therefore tested 10 additional subjects to find out whether a sweeping signal used in Bιkιsy audiometry would bring more detailed information on earplug attenuation. Mean attenuation was found to be somewhat closer to the nominal attenuation of the ER-9 and ER-15 earplugs up to about 1 kHz, whereas REAT measurements in sound field revealed more even attenuation at frequencies between 1 and 6 kHz. No significant association was found between earplug attenuation properties and earplug use. It was concluded that support and determination to get accustomed to hearing protector use are important

  16. Gravitational Lensing: Einstein's unfinished symphony

    Science.gov (United States)

    Treu, Tommaso; Ellis, Richard S.

    2015-01-01

    Gravitational lensing - the deflection of light rays by gravitating matter - has become a major tool in the armoury of the modern cosmologist. Proposed nearly a hundred years ago as a key feature of Einstein's theory of general relativity, we trace the historical development since its verification at a solar eclipse in 1919. Einstein was apparently cautious about its practical utility and the subject lay dormant observationally for nearly 60 years. Nonetheless there has been rapid progress over the past twenty years. The technique allows astronomers to chart the distribution of dark matter on large and small scales thereby testing predictions of the standard cosmological model which assumes dark matter comprises a massive weakly-interacting particle. By measuring the distances and tracing the growth of dark matter structure over cosmic time, gravitational lensing also holds great promise in determining whether the dark energy, postulated to explain the accelerated cosmic expansion, is a vacuum energy density or a failure of general relativity on large scales. We illustrate the wide range of applications which harness the power of gravitational lensing, from searches for the earliest galaxies magnified by massive clusters to those for extrasolar planets which temporarily brighten a background star. We summarise the future prospects with dedicated ground and space-based facilities designed to exploit this remarkable physical phenomenon.

  17. Gravitational Lensing - Einstein's Unfinished Symphony

    CERN Document Server

    Treu, Tommaso

    2014-01-01

    Gravitational lensing - the deflection of light rays by gravitating matter - has become a major tool in the armoury of the modern cosmologist. Proposed nearly a hundred years ago as a key feature of Einstein's theory of General Relativity, we trace the historical development since its verification at a solar eclipse in 1919. Einstein was apparently cautious about its practical utility and the subject lay dormant observationally for nearly 60 years. Nonetheless there has been rapid progress over the past twenty years. The technique allows astronomers to chart the distribution of dark matter on large and small scales thereby testing predictions of the standard cosmological model which assumes dark matter comprises a massive weakly-interacting particle. By measuring distances and tracing the growth of dark matter structure over cosmic time, gravitational lensing also holds great promise in determining whether the dark energy, postulated to explain the accelerated cosmic expansion, is a vacuum energy density or a...

  18. Franck: Father of the Organ Symphony

    OpenAIRE

    Verdin, Joris

    2014-01-01

    New light on the performance of Frabnck's Organ Works, explained and demonstrated by Joris Verdin at the organ of Royaumont (F). Commentaries and Performance of harmonium pieces by Franck, at the Mustel 1874 harmonium d'art.

  19. The gravitational wave symphony of the Universe

    Indian Academy of Sciences (India)

    B S Sathyaprakash

    2001-04-01

    The new millennium will see the upcoming of several ground-based interferometric gravitational wave antennas. Within the next decade a space-based antenna may also begin to observe the distant Universe. These gravitational wave detectors will together operate as a network taking data continuously for several years, watching the transient and continuous phenomena occurring in the deep cores of astronomical objects and dense environs of the early Universe where gravity was extremely strong and highly nonlinear. The network will listen to the waves from rapidly spinning non-axisymmetric neutron stars, normal modes of black holes, binary black hole inspiral and merger, phase transitions in the early Universe, quantum fluctuations resulting in a characteristic background in the early Universe. The gravitational wave antennas will open a new window to observe the dark Universe unreachable via other channels of astronomical observations.

  20. Hadronic octaves: Symphony in treble clef

    International Nuclear Information System (INIS)

    Pythagoreanism, as derived from the physics of music, an artificial quantized system, involved simple ratios between integers and was conjectured by the Pythagoreans to extend to the whole of physics (the Music of the Spheres). It hit the jackpot in 1895 with Balmer's formula and has dominated XXth Century physics, with its Quantum Foundations. I review the history of Hadron Spectroscopy and my personal role in 1958-1964, i.e. (1) my 1960 discovery of SU(3) symmetry with an octet assignment for the j = (1/2) baryons (independently reached somewhat later by M. Gell-Mann), and (2) in 1961 (with H. Goldberg) my mathematical construction of a structural model which was then developed into the physical quark model by Gell-Mann and Zweig

  1. Sound Exposure of Symphony Orchestra Musicians

    DEFF Research Database (Denmark)

    Schmidt, Jesper Hvass; Pedersen, Ellen Raben; Juhl, Peter Møller;

    2011-01-01

    exposure depends significantly on the specific instrument and the repertoire played by the exposed musician. Concerts, group rehearsals and individual practice were all significant contributors to the sound exposure. The highest LAeq of 86 –98 dB was found among the brass players. High string players were......Background: Assessment of sound exposure by noise dosimetry can be challenging especially when measuring the exposure of classical orchestra musicians where sound originate from many different instruments. A new measurement method of bilateral sound exposure of classical musicians was developed and...... levels exceeding LAeq8h of 85 dB.Conclusions: Binaural recording of the individual sound exposure showed that orchestra musicians could be exposed differently to the left and right ear and that they were primarily exposed from their own instruments. Specific repertoires as well as the specific instrument...

  2. 某市交响乐团员工健康危险因素与健康相关工作效率低下相关性研究%Risk factors and health-related inefficiency in a metropolitan symphony orchestra

    Institute of Scientific and Technical Information of China (English)

    张晓方; 黄建始; 何敛; 朱烨; 张黎刚; 王颖; 邓晓倩

    2010-01-01

    目的 探讨某市交响乐团员工健康危险因素与健康相关工作效率低下是否有关联.方法 通过文献查阅和专家咨询查找,确认了12个健康危险因素并对密歇根大学的健康危险因素评估问卷进行了修改,用于某市交响乐团员131名员工的健康危险因素评估.在问卷调查的同时还对其员工进行了躯体健康检查.结果 12个健康危险因素中,压力大占69.4%,其次分别为自我感觉健康差(60.3%)、吸烟(57.0%)、身体活动少(43.8%)、血压高(38.8%)和超重/肥胖(37.2%).女性比男性(Z=-2.117,P=0.034)、年龄≤38岁的员工比年龄>38岁的员工(Z=-2.748,P=0.006)、学历大学及以上的员工比学历在大学以下的员工(Z=-2.151,P=0.032)的工作效率低下等级要高.压力大和生活满意度差与健康相关工作效率低下有关(压力大,OR=7.045,95%CI:1.627~30.507;生活满意度差,OR=7.229,95%CI:1.455~35.921).结论 健康危险因素和健康相关工作效牢低下有关联.%Objective To investigate the association between risk factors and health-related inefficiency in a symphony orchestra. Methods The modified Michigan' s Health Risk Appraisal Questionnaire was used for the assessment of health risk factors. Based on the Health Risk Factors and Work Inefficiency Questionnaire was developed for this cross-section study in 131 the symphony orchestra employees. Results Higher stress, poor self-reported health, current smoking, physical inactivity, hypertension, and over-weight/obesity was reported in 69. 4% , 60. 3% , 57.0% , 43. 8% , 38. 8% , and 37. 2% employees, respectively. Work inefficiency was more commonly seen in female (χ2 =6. 629, P = 0.010),≤38 year-old (χ2 =5. 873, P =0.016), and highly educated staff (P = 0. 032). Higher stress and life dissatisfaction were associated with work inefficiency (higher stress; OR = 7.045,95% CI; 1.627-30.507 ;life dissatisfaction: OR = 7. 229,95% CI: 1. 455-35. 921). Conclusion Health risk

  3. Examining the situation of classical guitar in symphony orchestra’s concert programmes in Turkey with respect to different variablesTürkiye’deki senfoni orkestralarının konser programlarında klasik gitarın yer alma durumunun çeşitli değişkenler açısından incelenmesi

    Directory of Open Access Journals (Sweden)

    Soner Uluocak

    2015-02-01

    Full Text Available This study was designed to investigate the situation of the classical guitar in concert programs of symphony orchestras in Turkey with respect to different variables. The sample in the research, which was carried out by survey method, is consist of the concert programs of ten symphony orchestras between the period of foundation dates and the 2013-14 concert season. In data collection process the archives of the related orchestras was searched and analysed. The gathered data analysed by frequency and percentage method. The result shows that classical guitar pieces were appeared to some extent in concert programs of the symphony orchestras in Turkey. The frequencies of the appearence of the clasical guitar pieces in the concert programs had increased through the years. This increment has gained an acceleration since 1990. The large majority of the classical guitar pieces were belonged to the 20.th century composers and the most played classical guitar piece was Concierto de Aranjuez by Rodrigo. Appearance of the Turkish pieces in the programs were very low. Until the year 2000 the great majority of the guitarists that played with the orchestras were foreigner but since 2000 Turkish guitarist were appeared mostly on stages. ÖzetBu araştırma Türkiye’de faaliyet göstermekte olan senfoni orkestralarının konser programlarında klasik gitarın yer alma durumunun çeşitli değişkenler açısından incelenmesi amacıyla yapılmıştır. Survey yöntemi kullanılarak yapılan araştırmanın örneklemini Türkiye’de faaliyet göstermekte olan kamu ve özel sektöre ait toplam on senfoni orkestrasının, kuruluş yıllarından 2013-14 konser sezonuna değin gerçekleştirdikleri konser programları oluşturmaktadır. Araştırmada verilerin toplanması aşamasında ilgili orkestraların arşivleri taranarak, kuruluş yıllarından 2013-14 konser sezonuna değin var olan konser programları incelenmiş, verilerin değerlendirilmesinde ise

  4. A virtual symphony orchestra for studies on concert hall acoustics

    OpenAIRE

    Pätynen, Jukka

    2011-01-01

    Traditionally, concert hall acoustics is evaluated by listening to live concerts, which makes a direct comparison challenging. This thesis presents new tools and methods in the domain of the room acoustics evaluation, studies, and auralization. Auralization stands for the process of rendering an existing or modeled acoustic space in a way that it can be presented to the listener as he/she was listening to a sound inside the space under study. An essential topic in this thesis is a framew...

  5. Reflections on Measuring Thinking, while Listening to Mozart's "Jupiter" Symphony.

    Science.gov (United States)

    Wasserman, Selma

    1989-01-01

    Reflects on educators' current preoccupation with assessment of higher order thinking skills. Easy-to-mark, forced-choice, pencil-and-paper tests with single numerical scores may trivialize the wonderful complexity of human capabilities. Includes 17 references. (MLH)

  6. El departamento musical Disney : las Silly Symphonies y Carl Stalling

    OpenAIRE

    Duarte del Moral, Marina

    2014-01-01

    La historia de la animación tiene un nombre propio: Walt Disney. Gracias a su experimentación en diversos campos de esta materia, Disney consigue desarrollar la animación y su universo de una forma perseverante y continua, adaptándose a los diversos cambios producidos desde el nacimiento de ésta, reinventando una y otra vez el sector y añadiendo su toque mágico a la personalidad de cada personaje y cada obra. En este camino no está solo gracias al trabajo de genios como Carl Stalling, que apo...

  7. A symphony of inner ear developmental control genes

    Directory of Open Access Journals (Sweden)

    Kraus Petra

    2010-07-01

    Full Text Available Abstract The inner ear is one of the most complex and detailed organs in the vertebrate body and provides us with the priceless ability to hear and perceive linear and angular acceleration (hence maintain balance. The development and morphogenesis of the inner ear from an ectodermal thickening into distinct auditory and vestibular components depends upon precise temporally and spatially coordinated gene expression patterns and well orchestrated signaling cascades within the otic vesicle and upon cellular movements and interactions with surrounding tissues. Gene loss of function analysis in mice has identified homeobox genes along with other transcription and secreted factors as crucial regulators of inner ear morphogenesis and development. While otic induction seems dependent upon fibroblast growth factors, morphogenesis of the otic vesicle into the distinct vestibular and auditory components appears to be clearly dependent upon the activities of a number of homeobox transcription factors. The Pax2 paired-homeobox gene is crucial for the specification of the ventral otic vesicle derived auditory structures and the Dlx5 and Dlx6 homeobox genes play a major role in specification of the dorsally derived vestibular structures. Some Micro RNAs have also been recently identified which play a crucial role in the inner ear formation.

  8. A symphony of inner ear developmental control genes.

    Science.gov (United States)

    Chatterjee, Sumantra; Kraus, Petra; Lufkin, Thomas

    2010-01-01

    The inner ear is one of the most complex and detailed organs in the vertebrate body and provides us with the priceless ability to hear and perceive linear and angular acceleration (hence maintain balance). The development and morphogenesis of the inner ear from an ectodermal thickening into distinct auditory and vestibular components depends upon precise temporally and spatially coordinated gene expression patterns and well orchestrated signaling cascades within the otic vesicle and upon cellular movements and interactions with surrounding tissues. Gene loss of function analysis in mice has identified homeobox genes along with other transcription and secreted factors as crucial regulators of inner ear morphogenesis and development. While otic induction seems dependent upon fibroblast growth factors, morphogenesis of the otic vesicle into the distinct vestibular and auditory components appears to be clearly dependent upon the activities of a number of homeobox transcription factors. The Pax2 paired-homeobox gene is crucial for the specification of the ventral otic vesicle derived auditory structures and the Dlx5 and Dlx6 homeobox genes play a major role in specification of the dorsally derived vestibular structures. Some Micro RNAs have also been recently identified which play a crucial role in the inner ear formation. PMID:20637105

  9. Distortion product otoacoustic emission fine structure of symphony orchestra musicians

    DEFF Research Database (Denmark)

    Reuter, Karen; Hammershøi, Dorte

    Otoacoustic emissions (OAE) are sounds produced by the healthy inner ear. They can be measured as low-level signals in the ear canal and are used to monitor the functioning of outer hair cells.Several studies indicate that OAE might be a more sensitive measure to detect early noise-induced hearing...... losses than puretone audiometry. The distortion product otoacoustic emission (DPOAE) fine structure is obtained when the ear is stimulated by dual tone stimuli using a high frequency resolution. It is characterized by quasi-periodic variations across frequency, as it can be observed in the hearing...

  10. Distortion product otoacoustic emission fine structure of symphony orchestra musicians

    DEFF Research Database (Denmark)

    Reuter, Karen; Hammershøi, Dorte

    2006-01-01

    Otoacoustic emissions (OAE) are sounds produced by the healthy inner ear. They can be measured as low-level signals in the ear canal and are used to monitor the functioning of outer hair cells. Many studies indicate that OAE might be a more sensitive measure to detect early noise-induced haring...... losses than pure-tone audiometry. The distortion product otoacoustic emission (DPOAE) fine structure is obtained when the ear is stiumulated by dual tone stimuli using a high frequency resolution. It is characterized by quasi-periodic variations across frequency, as it can be observed in the hearing...

  11. Cyclin B1: conductor of mitotic symphony orchestra

    Institute of Scientific and Technical Information of China (English)

    Huijuan Yu; Xuebiao Yao

    2008-01-01

    @@ The inheritance of human genome through mitosis is precisely regulated by a series of tightly orchestrated events such as chromosome condensation, biorientated spindle formation, chromosome congression, segregation and cytokinesis.

  12. The black hole symphony: probing new physics using gravitational waves.

    Science.gov (United States)

    Gair, Jonathan R

    2008-12-13

    The next decade will very likely see the birth of a new field of astronomy as we become able to directly detect gravitational waves (GWs) for the first time. The existence of GWs is one of the key predictions of Einstein's theory of general relativity, but they have eluded direct detection for the last century. This will change thanks to a new generation of laser interferometers that are already in operation or which are planned for the near future. GW observations will allow us to probe some of the most exotic and energetic events in the Universe, the mergers of black holes. We will obtain information about the systems to a precision unprecedented in astronomy, and this will revolutionize our understanding of compact astrophysical systems. Moreover, if any of the assumptions of relativity theory are incorrect, this will lead to subtle, but potentially detectable, differences in the emitted GWs. Our observations will thus provide very precise verifications of the theory in an as yet untested regime. In this paper, I will discuss what GW observations could tell us about known and (potentially) unknown physics. PMID:18812300

  13. Symphony: A Framework for Accurate and Holistic WSN Simulation

    Directory of Open Access Journals (Sweden)

    Laurynas Riliskis

    2015-02-01

    Full Text Available Research on wireless sensor networks has progressed rapidly over the last decade, and these technologies have been widely adopted for both industrial and domestic uses. Several operating systems have been developed, along with a multitude of network protocols for all layers of the communication stack. Industrial Wireless Sensor Network (WSN systems must satisfy strict criteria and are typically more complex and larger in scale than domestic systems. Together with the non-deterministic behavior of network hardware in real settings, this greatly complicates the debugging and testing of WSN functionality. To facilitate the testing, validation, and debugging of large-scale WSN systems, we have developed a simulation framework that accurately reproduces the processes that occur inside real equipment, including both hardware- and software-induced delays. The core of the framework consists of a virtualized operating system and an emulated hardware platform that is integrated with the general purpose network simulator ns-3. Our framework enables the user to adjust the real code base as would be done in real deployments and also to test the boundary effects of different hardware components on the performance of distributed applications and protocols. Additionally we have developed a clock emulator with several different skew models and a component that handles sensory data feeds. The new framework should substantially shorten WSN application development cycles.

  14. Symphony: a framework for accurate and holistic WSN simulation.

    Science.gov (United States)

    Riliskis, Laurynas; Osipov, Evgeny

    2015-01-01

    Research on wireless sensor networks has progressed rapidly over the last decade, and these technologies have been widely adopted for both industrial and domestic uses. Several operating systems have been developed, along with a multitude of network protocols for all layers of the communication stack. Industrial Wireless Sensor Network (WSN) systems must satisfy strict criteria and are typically more complex and larger in scale than domestic systems. Together with the non-deterministic behavior of network hardware in real settings, this greatly complicates the debugging and testing of WSN functionality. To facilitate the testing, validation, and debugging of large-scale WSN systems, we have developed a simulation framework that accurately reproduces the processes that occur inside real equipment, including both hardware- and software-induced delays. The core of the framework consists of a virtualized operating system and an emulated hardware platform that is integrated with the general purpose network simulator ns-3. Our framework enables the user to adjust the real code base as would be done in real deployments and also to test the boundary effects of different hardware components on the performance of distributed applications and protocols. Additionally we have developed a clock emulator with several different skew models and a component that handles sensory data feeds. The new framework should substantially shorten WSN application development cycles. PMID:25723144

  15. Design, Development and Evaluation of an Adaptive and Standardized RTCP-based IDMS Solution

    OpenAIRE

    Montagud Climent, Mario

    2015-01-01

    Nowadays, we are witnessing a transition from physical togetherness towards networked togetherness around media content. Novel forms of shared media experiences are gaining momentum, allowing geographically distributed users to concurrently consume the same media content while socially interacting (e.g., via text, audio or video chat). Relevant use cases are, for example, Social TV, networked games and multi-party conferencing. However, realizing enjoyable shared media services faces many cha...

  16. PLD-IDMS studies towards direct measurement of burn-up of nuclear fuel

    International Nuclear Information System (INIS)

    A method based on Pulsed laser deposition followed by Isotope dilution mass spectrometric method is evaluated towards the possibility of direct measurement of burn up of nuclear fuel and also to find out spatial distribution of burn-up along the pellet. The wave length dependent results show larger error with 1064 nm, compared to 532 nm laser beam. Much less error is expected with shorter wave length and shorter pulse width laser beam. Further work is being carried out in this direction

  17. bwIDM : Föderieren auch nicht-webbasierter Dienste auf Basis von SAML

    OpenAIRE

    Simon, Michael; Waldvogel, Marcel; Schober, Sven; Semaan, Saher; Nussbaumer, Martin

    2012-01-01

    Zur organisationsübergreifenden Nutzung von IT-Diensten werden Dienst- Föderationen gebildet. Dabei kann das Nutzerkonto der sogenannten Heimateinrichtung auch zum Zugriff auf nicht-lokale Dienste genutzt werden. Während die Integration webbasierter Dienste in Föderationen mit SAML und beispielsweise Shibboleth mittlerweile in vielen Anwendungsbereichen allgegenwärtig ist, fällt die Integration nicht-webbasierter IT-Dienste schwer. Existierende Ansätze, mit denen sich prinzipiell auch nicht-w...

  18. Design, development and assessment of control schemes for IDMS in a standardized RTCP-based solution

    NARCIS (Netherlands)

    Montagud, M.; Boronat, F.; Stokking, H.M.; Cesar, P.

    2014-01-01

    Currently, several media sharing applications that allow social interactions between distributed users are gaining momentum. In these networked scenarios, synchronized playout between the involved participants must be provided to enable truly interactive and coherent shared media experiences. This r

  19. Chronic obstructive pulmonary disease and glucose metabolism: a bitter sweet symphony

    Directory of Open Access Journals (Sweden)

    Mirrakhimov Aibek E

    2012-10-01

    Full Text Available Abstract Chronic obstructive pulmonary disease, metabolic syndrome and diabetes mellitus are common and underdiagnosed medical conditions. It was predicted that chronic obstructive pulmonary disease will be the third leading cause of death worldwide by 2020. The healthcare burden of this disease is even greater if we consider the significant impact of chronic obstructive pulmonary disease on the cardiovascular morbidity and mortality. Chronic obstructive pulmonary disease may be considered as a novel risk factor for new onset type 2 diabetes mellitus via multiple pathophysiological alterations such as: inflammation and oxidative stress, insulin resistance, weight gain and alterations in metabolism of adipokines. On the other hand, diabetes may act as an independent factor, negatively affecting pulmonary structure and function. Diabetes is associated with an increased risk of pulmonary infections, disease exacerbations and worsened COPD outcomes. On the top of that, coexistent OSA may increase the risk for type 2 DM in some individuals. The current scientific data necessitate a greater outlook on chronic obstructive pulmonary disease and chronic obstructive pulmonary disease may be viewed as a risk factor for the new onset type 2 diabetes mellitus. Conversely, both types of diabetes mellitus should be viewed as strong contributing factors for the development of obstructive lung disease. Such approach can potentially improve the outcomes and medical control for both conditions, and, thus, decrease the healthcare burden of these major medical problems.

  20. Dangling conversations: web-forum use by a symphony orchestra's audience members

    OpenAIRE

    O'Sullivan, Terry

    2010-01-01

    Interactive online communication forms an increasingly common adjunct to consumption of products and services, notably arts and entertainment. This paper aims to contribute to arts marketers' understanding of web-forum use by arts audience members, in order to guide thinking about the role of online interaction in their communication strategy. Rather than the participant (or non-participant) observation favoured by 'netnographic' research (Kozinets, 2002), the methodology here consists of a d...

  1. Resurrection Symphony: "El Sistema" as Ideology in Venezuela and Los Angeles

    Science.gov (United States)

    Fink, Robert

    2016-01-01

    The explosive growth of Venezuela's "El Sistema" is rewriting the agenda of musical education in the West. Many commentators from the world of classical music react to the spectacle of dedicated young colonial musicians playing European masterworks as a kind of "miracle," accepting "Sistema" founder José Antonio…

  2. Transfer method of conducting in the symphony orchestra of the Hanoi National Conservatory of Music, Vietnam

    Directory of Open Access Journals (Sweden)

    Parichat Wiang-in

    2015-11-01

    Full Text Available This is a qualitative designed and conducted with two primary research aims, which were: 1 To study the life and experiences of symphonic orchestra conductors in Hanoi, Vietnam; 2 To study the inheritance process for conductors of the symphonic orchestra in Hanoi, Vietnam. The research area for this investigation was purposively selected as the Vietnam National Academy of Music in Hanoi. The investigation began in October 2012 and was concluded in January 2014. The two key informants for this investigation were expert conductors and teachers at the academy, Dr. Nguyễn Phúc Linh and Dr. Nguyễn Thiếu Hoa. Data was collected from a combination of document analysis and field research. Tools used for data collection included interviews, participant and non-participant observation and focus group discussions. Results show that both of the key informants for this investigation were born into families of artists and had a particularly close relationship with traditional folk art. Scholarships to study abroad at the Tchaikovsky University, Russia enabled them to learn from Russian conductors and they developed the skills that have now led them to be recognized as being among the most accomplished conductors in Vietnam. The process of instruction preferred by these two academics is taught in three steps: the preparation stage, the teaching stage and the assessment and evaluation stage. The benefits of studying with Dr. Nguyễn Phúc Linh and Dr. Nguyễn Thiếu Hoa are the cumulative experiences of international conducting practices and the high standards that the two academics possess and demand.

  3. The inaudible symphony: on the detection and source identification of atmospheric infrasound

    NARCIS (Netherlands)

    Evers, L.G.

    2008-01-01

    Sound becomes inaudible if it consists of frequencies lower than 20 Hz, i.e. the human hearing threshold, and is called infrasound. Low frequency acoustic signals were first discovered after the eruption of the Krakatoa (Indonesia) in 1883. Due to its low frequency content, this infrasound traveled

  4. Hearing loss in relation to sound exposure of professional symphony orchestra musicians

    DEFF Research Database (Denmark)

    Schmidt, J. H.; Pedersen, E. R.; Paarup, H. M.;

    2014-01-01

    B compared with the 238 ears with lowest exposure. The observed hearing loss of musicians was smaller compared with the noise-induced permanent threshold shift (NIPTS) predicted from ISO1999. A remaining confounding effect of age after ISO7029 age corrections could be observed to explain the difference...... in observed and predicted NIPTS. However, the observed hearing loss difference between the left and the right ear of musicians was 2.5 dB (95% confidence interval 1.5-3.6), which was similar to the NIPTS predicted from ISO1999. Most of the musicians had better hearing at 3, 4, and 6 kHz for age than expected...

  5. A Bitter Sweet Symphony: Immune Responses to Altered O-glycan Epitopes in Cancer

    OpenAIRE

    Lenneke A.M. Cornelissen; Van Vliet, Sandra J.

    2016-01-01

    The appearance of aberrant glycans on the tumor cell surface is one of the emerging hallmarks of cancer. Glycosylation is an important post-translation modification of proteins and lipids and is strongly affected by oncogenesis. Tumor-associated glycans have been extensively characterized regarding their composition and tumor-type specific expression patterns. Nevertheless whether and how tumor-associated glycans contribute to the observed immunomodulatory actions by tumors has not been exten...

  6. THE SYMPHONY OF TULIPS IN THE POST-ACCESSION STRATEGY OF THE CITY OF PITESTI

    OpenAIRE

    Mihaela, ASANDEI; Andreea-Daniela, GANGONE

    2013-01-01

    This paper aims to analyse an identity element of the city of Pitesti, based on the results of a study that helped design the town’s post-accession strategy. Local development strategies have become essential for administrative reform in Central and Eastern European countries, ensuring the competitiveness of cities in the context of an increasing regional and international competition. Urban marketing approaches the problems of urban design and organization, as it seeks to meet the needs of a...

  7. A Bitter Sweet Symphony: Immune Responses to Altered O-glycan Epitopes in Cancer

    Science.gov (United States)

    Cornelissen, Lenneke A.M.; Van Vliet, Sandra J.

    2016-01-01

    The appearance of aberrant glycans on the tumor cell surface is one of the emerging hallmarks of cancer. Glycosylation is an important post-translation modification of proteins and lipids and is strongly affected by oncogenesis. Tumor-associated glycans have been extensively characterized regarding their composition and tumor-type specific expression patterns. Nevertheless whether and how tumor-associated glycans contribute to the observed immunomodulatory actions by tumors has not been extensively studied. Here, we provide a detailed overview of the current knowledge on how tumor-associated O-glycans affect the anti-tumor immune response, thereby focusing on truncated O-glycans present on epithelial tumors and mucins. These tumor-associated O-glycans and mucins bind a variety of lectin receptors on immune cells to facilitate the subsequently induction of tolerogenic immune responses. We, therefore, postulate that tumor-associated glycans not only support tumor growth, but also actively contribute to immune evasion. PMID:27153100

  8. Simfonija bolezni - poklicne bolezni glasbenikov: A symphony of maladies - occupational diseases in musicians:

    OpenAIRE

    Bilban, Marjan; Hojs, Nina

    2010-01-01

    Almost half of the musicians are confronted with playing-related health problems. The characteristics of an individual performer and the type of musical instrument played determine the musician's health problems. These are mainly musculosceletal ( overuse syndrome ), neurologic (entrapement neuropathies, focal dystonias), dermatologic, otolaryngologic and psychologic disorders. Other possible health problems are dental, cardiovascular, respiratory and ophtalmic. Although these health problems...

  9. Molecular symphony of tooth–jawbone morphogenesis and related disorders. Part 1: Morphogenesis

    Czech Academy of Sciences Publication Activity Database

    Matalová, Eva; Fleischmannová, Jana; Krejčí, P.; Míšek, Ivan

    2009-01-01

    Roč. 18, č. 4 (2009), 15-21. ISSN 1210-4272 R&D Projects: GA ČR GC524/08/J032 Institutional research plan: CEZ:AV0Z50450515 Keywords : odontogenesis * osteogenesis * dental disorders Subject RIV: FF - HEENT, Dentistry

  10. Molecular symphony of tooth - bone morphogenesis and related disorders, Part 2: Remodelling and defects

    Czech Academy of Sciences Publication Activity Database

    Krejčí, P.; Matalová, Eva; Fleischmannová, Jana; Míšek, Ivan

    2009-01-01

    Roč. 18, č. 5 (2009), 14-21. ISSN 1210-4272 R&D Projects: GA ČR GC524/08/J032 Institutional research plan: CEZ:AV0Z50450515 Keywords : odontogenesis * osteogenesis * dental disorders Subject RIV: FF - HEENT, Dentistry

  11. It's a bittersweet symphony: simultaneously mixed emotional responses to music with conflicting cues.

    Science.gov (United States)

    Larsen, Jeff T; Stastny, Bradley J

    2011-12-01

    Some evidence indicates that emotional reactions to music can be organized along a bipolar valence dimension ranging from pleasant states (e.g., happiness) to unpleasant states (e.g., sadness), but songs can contain some cues that elicit happiness (e.g., fast tempos) and others that elicit sadness (e.g., minor modes). Some models of emotion contend that valence is a basic building block of emotional experience, which implies that songs with conflicting cues cannot make people feel happy and sad at the same time. Other models contend that positivity and negativity are separable in experience, which implies that music with conflicting cues might elicit simultaneously mixed emotions of happiness and sadness. Hunter, Schellenberg, and Schimmack (2008) tested these possibilities by having subjects report their happiness and sadness after listening to music with conflicting cues (e.g., fast songs in minor modes) and consistent cues (e.g., fast songs in major modes). Results indicated that music with conflicting cues elicited mixed emotions, but it remains unclear whether subjects simultaneously felt happy and sad or merely vacillated between happiness and sadness. To examine these possibilities, we had subjects press one button whenever they felt happy and another button whenever they felt sad as they listened to songs with conflicting and consistent cues. Results revealed that subjects spent more time simultaneously pressing both buttons during songs with conflicting, as opposed to consistent, cues. These findings indicate that songs with conflicting cues can simultaneously elicit happiness and sadness and that positivity and negativity are separable in experience. PMID:21707144

  12. Smorgasbord or symphony? Assessing public health nutrition policies across 30 European countries using a novel framework

    OpenAIRE

    Lloyd-Williams, Ffion; Bromley, Helen; Orton, Lois; Hawkes, Corinna, ed.; Taylor-Robinson, David; O’Flaherty, Martin; McGill, Rory; Anwar, Elspeth; Hyseni, Lirije; Moonan, May; Rayner, Mike; Capewell, Simon

    2014-01-01

    Background Countries across Europe have introduced a wide variety of policies to improve nutrition. However, the sheer diversity of interventions represents a potentially bewildering smorgasbord. We aimed to map existing public health nutrition policies, and examine their perceived effectiveness, in order to inform future evidence-based diet strategies. Methods We created a public health nutrition policy database for 30 European countries . National nutrition policies were classified and assi...

  13. Symphony and cacophony in ion track etching: how to control etching results

    Czech Academy of Sciences Publication Activity Database

    Fink, Dietmar; Kiv, A.; Cruz, S. A.; Munoz, G. H.; Vacík, Jiří

    2012-01-01

    Roč. 167, č. 7 (2012), s. 527-540. ISSN 1042-0150 R&D Projects: GA AV ČR IAA200480702 Institutional support: RVO:61389005 Keywords : ion tracks * polymers * etching * diodes * resistances Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders Impact factor: 0.502, year: 2012

  14. TAHSĐN YÜCEL'S SHORT STORIES IN HIS BOOK 'MYSELF AND THE OTHER’ READING WITH THE 9th SYMPHONY OR THE CIRCUMSTANCES OF ÖTEGEÇE'S IN THE RHYTM OF 9th SYMPHONY

    Directory of Open Access Journals (Sweden)

    Ferhan AKGÜN (M.A.H.

    2009-01-01

    Full Text Available Literary works transforming in time have started toemerge in especially personal inclinations, psychologicalanalysis and universal matters; and have pushed thelimit lines lately. This limit was not only all about thecontent of the literature but also reflected towards theother fields of art. This intertextuality forms the roots ofhis short stories within “Me and the Others” by TahsinYücel, who is among the short story writers of 1950s.Tahsin Yücel expreses this in his words: “there exists arelation between the smallest and the greatest structures,between my structure and the others’. Reflecting theindividual and his inner world, departing from theindividual and giving messages to the society andhumankind, the writer endeavours to reach from localmatters to universal ones in his short stories within “Meand the Others”.

  15. Intervjuu American Wind Symphony Orchestra dirigendi Robert Austin Boudreau'ga = Interview with Mr. Robert Austin Boudreau, director of the American Wind Symphony Orchestra / Robert Austin Boudreau ; interv. Heli Ojamaa

    Index Scriptorium Estoniae

    Boudreau, Robert Austin

    2007-01-01

    11. IV 2007. a. tehtud telefoniintervjuu Robert A. Boudreau'ga, kellele arhitekt Louis I. Kahn disainis kontserdilaevad Point Counterpoint I (valmis 1961) ja Point Counterppoint II (kavandamist alustati 1966, valmis 1975). Louis I. Kahnist, koostööst arhitektiga ja laevadest. Selgitav kaaskiri arhitekt Heli Ojamaalt. Ill.: I laeva makett, II laeva joonised ja 4 värv. fotot

  16. Symphonies of urban places : Urban rhythms as traces of time in space. A study of "urban rhythms" / Filipa Matos Wunderlich

    Index Scriptorium Estoniae

    Wunderlich, Filipa Matos

    2008-01-01

    Rütmi mõistest, linna rütmidest kui igapäevase elu ja ruumirütmide tervikust, kui uuest võimalusest analüüsida linnakeskkonda, kui täiendusest traditsiooniliste linnaprobleemide lahendamisele

  17. Executive functions cannot be distinguished from general intelligence: Two variations on a single theme within a symphony of latent variance

    Directory of Open Access Journals (Sweden)

    Donald R Royall

    2014-10-01

    Full Text Available The empirical foundation of executive control function (ECF remains controversial. We have employed structural equation models (SEM to explicitly distinguish domain-specific variance in ECF performance from memory (MEM and shared cognitive performance variance, i.e., Spearman’s g. ECF does not survive adjustment for both MEM and g in a well fitting model of data obtained from non-demented older persons (N = 193. Instead, the variance in putative ECF measures is attributable only to g, and related to functional status only through a fraction of that construct (i.e., dECF. dECF is a homolog of the latent variable δ, which we have previously associated specifically with the Default Mode Network (DMN. These findings undermine the validity of ECF and its putative association with the frontal lobe. ECF may have no existence independent of general intelligence, and no functionally salient association with the frontal lobe outside of that structure’s contribution to the DMN.

  18. Priming effect and microbial diversity in ecosystem functioning and response to global change: a modeling approach using the Symphony model

    OpenAIRE

    Perveen, Nazia; Barot, Sébastien; ALVAREZ, Gaël; Klumpp, Katja; Martin, Raphaël; Herfurth, Damien; Louault, Frédérique; Fontaine, Sébastien

    2014-01-01

    Integration of the priming effect (PE) in ecosystem models is crucial to better predict the consequences of global change on ecosystem carbon (C) dynamics and its feedbacks on climate. Over the last decade, many attempts have been made to model PE in soil. However, PE has not yet been incorporated into any ecosystem models. Here we build plant-soil models to explore how PE and microbial diversity influence soil-plant interactions and ecosystem C and nitrogen (N) dynamics in response to global...

  19. Priming effect and microbial diversity in ecosystem functioning and response to global change : a modeling approach using the SYMPHONY model

    OpenAIRE

    Perveen, N.; Barot, Sébastien; Alvarez, G; Klumpp, K.; R. Martin; Rapaport, A.; Herfurth, D.; Louault, F; Fontaine, S.

    2014-01-01

    Integration of the priming effect (PE) in ecosystem models is crucial to better predict the consequences of global change on ecosystem carbon (C) dynamics and its feedbacks on climate. Over the last decade, many attempts have been made to model PE in soil. However, PE has not yet been incorporated into any ecosystem models. Here, we build plant/soil models to explore how PE and microbial diversity influence soil/plant interactions and ecosystem C and nitrogen (N) dynamics in respo...

  20. 交响乐演奏速度研究%A Study of the Tempos in the Performances of Symphonies

    Institute of Scientific and Technical Information of China (English)

    文思隆

    2004-01-01

    通过采用实验心理学的方法,对56名音乐专业和非专业的志愿者以及31位世界著名指挥家的演出录音进行的测量证明:音乐专业人员速度辨别能力明显优于普通被试;在音乐表演中,传统交响乐的主题与副题、段落之间,甚至乐句的内部都可以进行速度的变化;相对速度关系的重要性超过了作曲家规定速度的重要性;把握交响乐的演奏速度,布局是关键;设计音乐演奏速度,要顺应人的速度感受性规律.

  1. A finely tuned symphony of factors modulates the microbial food web of a freshwater reservoir in spring

    Czech Academy of Sciences Publication Activity Database

    Šimek, Karel; Nedoma, Jiří; Znachor, Petr; Kasalický, Vojtěch; Jezbera, Jan; Horňák, Karel; Seďa, Jaromír

    2014-01-01

    Roč. 59, č. 5 (2014), s. 1477-1492. ISSN 0024-3590 R&D Projects: GA ČR(CZ) GA13-00243S Institutional support: RVO:60077344 Keywords : microbial food web * freshwater reservoir * limnology Subject RIV: EE - Microbiology, Virology Impact factor: 3.794, year: 2014

  2. Precise time and frequency intercomparison between NPL, India and PTB, Federal Republic of Germany via satellite symphonie-1

    Science.gov (United States)

    Mathur, B. S.; Banerjee, P.; Sood, P. C.; Saxena, M.; Kumar, N.; Suri, A. K.

    1981-01-01

    A time and frequency intercomparison experiment conducted using Earth stations in New Delhi, India and Raisting, FRG is described. The NPL clock was placed at New Delhi Earth Station and the Raisting Clock was calibrated with PTB/Primary standard via LORAN-C and travelling clocks. The random uncertainity of time comparisons, represented by two sample Allan Variance sigma (30 seconds), was less than 10 nanoseconds. The relative frequency difference between the NPL and Raisting Clocks, SNPL, RAIS, as measured over the 44 days period was found to be -15.7 x 10 to the -13th power. The relative frequency difference between PTB Primary Standard and Raisting Clock, SPTB, RAIS, during this period, was measured to be -22.8 x 10 to the -13th power. The relative frequency difference between NPL clock and PTB Primary Standard, SNPL, PTB, thus, is +7.1 x 10 to the -13th power. The clock rate (UTC, India) of +7.1 + or - 0.5 x 10 to the -13th power, agrees well with that obtained via VLF phase measurements over one year period and with USNO travelling clock time comparisons made in September, 1980.

  3. The effect of exercise on the absorption of inhaled human insulin via the AERx(R) iDMS in people with type 1 diabetes

    DEFF Research Database (Denmark)

    Petersen, Astrid Heide; Kohler, G; Korsatko, S;

    2007-01-01

    type 1 diabetes received a dose of 0.19 units/kg inhaled human insulin followed in random order by either 1) no exercise (NOEX), or 30 min exercise starting 2) 30 min after dosing (EX30), 3) 120 min after dosing (EX120), or 4) 240 min after dosing (EX240). RESULTS - Exercise changed the shape of the...

  4. Synthèse Formelle de Modèles de Systèmes Temps Réel dans une Approche IDM

    OpenAIRE

    Lelionnais, Cédrick; Delatour, Jérôme; Brun, Matthias; Roux, Olivier Henri; Seidner, Charlotte

    2014-01-01

    International audience —The development of real-time embedded systems is quite complex because of the wide range of execution platforms and of the importance of non-functional requirements. Further-more, Model Driven Engineering is particularly suitable for han-dling the diversity of implementation targets. Therefore, several real-time embedded systems development suites leverage Model Driven Engineering by automatically generating platform-specific code from high-level design models. Such...

  5. Anomalous id="M1" xmlns="http://www.w3.org/1998/Math/MathML">tqγ Couplings in id="M2" xmlns="http://www.w3.org/1998/Math/MathML">γp Collision at the LHC

    OpenAIRE

    M. Köksal; İnan, S. C.(Department of Physics, Cumhuriyet University, 58140 Sivas, Turkey)

    2014-01-01

    We have examined the constraints on the anomalous tqγ    (q=u,c) couplings through the process pp→pγp→pWbX at the LHC by considering four forward detector acceptances: 0.0015<ξ<0.5 , 0.0015<ξ<0.15 , 0.015<ξ<0.15 , and 0.1<ξ<0.5 , where ξ=Eγ/E with Eγ and E the energies of the photon and of the incoming proton, respectively. The sensitivity bounds on the anomalous couplings have been obtained at the 95% confidence level in a model independent effective Lagrangian approa...

  6. Neural rhythmic symphony of human walking observation: Upside-down and Uncoordinated condition on cortical theta, alpha, beta and gamma oscillations.

    Directory of Open Access Journals (Sweden)

    David eZarka

    2014-09-01

    Full Text Available Biological motion observation has been recognized to produce dynamic change in sensorimotor activation according to the observed kinematics. Physical plausibility of the spatial-kinematic relationship of human movement may play a major role in the top-down processing of human motion recognition. Here, we investigated the time course of scalp activation during observation of human gait in order to extract and use it on future integrated brain-computer interface using virtual reality (VR. We analyzed event related potentials (ERP, the event related spectral perturbation (ERSP and the inter-trial coherence (ITC from high-density EEG recording during video display onset (-200 to 600 ms and the steady state visual evoked potentials (SSVEP inside the video of human walking 3D-animation in three conditions: Normal; Upside-down (inverted images; and Uncoordinated (pseudo-randomly mixed images. We found that early visual evoked response P120 was decreased in Upside-down condition. The N170 and P300b amplitudes were decreased in Uncoordinated condition. In Upside-down and Uncoordinated conditions, we found decreased alpha power and theta phase-locking. As regards gamma oscillation, power was increased during the Upside-down animation and decreased during the Uncoordinated animation. An SSVEP-like response oscillating at about 10 Hz was also described showing that the oscillating pattern is enhanced 300 ms after the heel strike event only in the Normal but not in the Upside-down condition. Our results are consistent with most of previous point-light display studies, further supporting possible use of virtual reality for neurofeedback applications.

  7. 对话与独白——论李松涛《忧患交响曲》%Dialogues and Monologues: on Li Songtao's Symphony of Hardship

    Institute of Scientific and Technical Information of China (English)

    黄平

    2009-01-01

    @@ 一、对话型诗人与独白型诗人 眉毛,是情绪的小道具 无足轻重却高高在上 对酸甜苦辣它没有发言权 --不少人恰是社会的眉毛 可诗人正相反 `他是眉侧的耳朵, 他是眉下的眼睛和嘴巴, 是接收器!是监视器!是报警器!①

  8. Muusikamaailm : Kümme aastat Rheinsbergi festivali. Birminghami Symphony Hall 10. "Tampereen Sävel". Vytautas Barkauskas 70. Alberto Erede lahkunud / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2001-01-01

    Rheinsbergi muusikafestivalist Saksamaal. Birminghami kontserdisaalist, juubelikontserdist. Koorifestivalist "Tampereen Sävel" Soomes. V. Barkauskase juubelikontserdist Vilniuses. Lühidalt A. Eredest

  9. Chemosensitivity Predicted by BluePrint 80-Gene Functional Subtype and MammaPrint in the Prospective Neoadjuvant Breast Registry Symphony Trial (NBRST)

    OpenAIRE

    Whitworth, Pat; Stork-Sloots, Lisette; de Snoo, Femke A.; Richards, Paul; Rotkis, Michael; Beatty, Jennifer; Mislowsky, Angela; Pellicane, James V.; Nguyen, Bichlien; Lee, Laura; Nash, Charles; Gittleman, Mark; Akbari, Stephanie; Beitsch, Peter D.

    2014-01-01

    Purpose The purpose of the NBRST study is to compare a multigene classifier to conventional immunohistochemistry (IHC)/fluorescence in situ hybridization (FISH) subtyping to predict chemosensitivity as defined by pathological complete response (pCR) or endocrine sensitivity as defined by partial response. Methods The study includes women with histologically proven breast cancer, who will receive neoadjuvant chemotherapy (NCT) or neoadjuvant endocrine therapy. BluePrint in combination with Mam...

  10. A Study of Transverse Momentum Distributions of Jets Produced in id="M1" xmlns="http://www.w3.org/1998/Math/MathML">p - id="M2" xmlns="http://www.w3.org/1998/Math/MathML">p , id="M3" xmlns="http://www.w3.org/1998/Math/MathML">p - id="M4" xmlns="http://www.w3.org/1998/Math/MathML">p- , id="M5" xmlns="http://www.w3.org/1998/Math/MathML">d -Au, Au-Au, and Pb-Pb Collisions at High Energies

    OpenAIRE

    Hua-Rong Wei; Fu-Hu Liu

    2015-01-01

    The transverse momentum distributions of jets produced in p - p , p - p- , d -Au, Au-Au, and Pb-Pb collisions at high energies with different selected conditions are analyzed by using a multisource thermal model. The multicomponent (mostly two-component) Erlang distribution used in our description is in good agreement with the experimental data measured by the STAR, D0, CDF II, ALICE, ATLAS, and CMS Collaborations. Related parameters are extracted from the transverse momentum distributions an...

  11. Chanting of the inner space: on symphonic and concertante works by Milorad Marinković

    OpenAIRE

    Janković-Beguš Jelena

    2015-01-01

    The opus of contemporary Serbian composer Milorad Marinković (b. 1976), which encompasses works of choral, chamber, concertante and symphony music, leans towards classical forms of artistic music, Serbian folklore music, and Serbian Orthodox church chant. This paper deals with pieces composed for larger instrumental ensembles: Herojska uvertira (Heroic Overture) for symphony orchestra, Psalmodija (Psalmody) for symphony orchestra, Koncert za klavir i orkest...

  12. Pion id="M1" xmlns="http://www.w3.org/1998/Math/MathML">pT Spectra in id="M2" xmlns="http://www.w3.org/1998/Math/MathML">p+p Collisions as a Function of id="M3" xmlns="http://www.w3.org/1998/Math/MathML">s and Event Multiplicity

    OpenAIRE

    Sett, Priyanka; Shukla, Prashant

    2014-01-01

    We study the charged pion transverse momentum (pT) spectra in p+p collisions as a function of collision energy s and event multiplicity using Tsallis distribution. This study gives an insight of the pion production process in p+p collisions. The study covers pion spectra measured in p+p collisions at SPS energies (6.27–17.27 GeV), RHIC energies (62.4 GeV and 200 GeV), and LHC energies (900 GeV, 2.76 TeV, and 7 TeV). The Tsallis parameters have been obtained and parameterized as a function of ...

  13. Introducing a new framework for using generic Information Delivery Manuals

    DEFF Research Database (Denmark)

    Mondrup, Thomas Fænø; Treldal, Niels; Karlshøj, Jan;

    2014-01-01

    to resolve this issue is based on the Information Delivery Manual (IDM). The IDMs in current use indicate that focus has mainly been on formalizing multifaceted and wide-ranging AEC/FM processes, and therefore often involve multiple use cases. Because IDMs typically describe such complex processes...

  14. 电子商务企业"定向网络营销系统"的研究%Study of Internet Directed Marketing System(IDMS) for E-Business Enterprise

    Institute of Scientific and Technical Information of China (English)

    吕军

    2001-01-01

    "定向网络营销"是"网络营销"向纵深方向的最新发展,它依托WEB数据库和eCRM(电子化客户关系管理),以全新的"一对一营销"和"持久关系营销"为理念,运用成熟的网络技术和数据库技术,解决现行"网络营销"中存在的显著问题,同时全面提升电子商务网站的网络营销管理质量.本文在大量研究国内外一流的电子商务网站的基础上,提出了基于数据挖掘的"定向网络营销系统"的系统设计模型.

  15. Convoluted id="M1" xmlns="http://www.w3.org/1998/Math/MathML">ν -Signals on 114Cd Isotope from Astrophysical and Laboratory Neutrino Sources

    OpenAIRE

    Tsakstara, Vaitsa

    2015-01-01

    At first, we evaluate scattering cross sections of low, and intermediate-energy neutrinos scattered off the 114 Cd isotope, the most abundant Cd isotope present also in the COBRA detector (CdTe and CdZnTe materials) which aims to search for double beta decay events and neutrino observations at Gran Sasso laboratory (LNGS). The coherent ν -nucleus channel addressed here is the dominant reaction channel of the neutral current ν -nucleus scattering. Our ν -nucleus cross sections (calculated with...

  16. id="M1" xmlns="http://www.w3.org/1998/Math/MathML">P-V Criticality of Conformal Anomaly Corrected AdS Black Holes

    OpenAIRE

    Liu, Wen-Biao; Mo, Jie-Xiong

    2015-01-01

    The effects of conformal anomaly on the thermodynamics of black holes are investigated in this paper from the perspective of P-V criticality of AdS black holes. Treating the cosmological constant as thermodynamic pressure, we extend the recent research to the extended phase space. Firstly, we study the P - V criticality of the uncharged AdS black holes with conformal anomaly and find that conformal anomaly does not influence whether there exists Van der Waals like critical behavior. Secondly,...

  17. Equal Area Laws and Latent Heat for id="M1" xmlns="http://www.w3.org/1998/Math/MathML">d -Dimensional RN-AdS Black Hole

    OpenAIRE

    Li-Chun Zhang; Hui-Hua Zhao; Ren Zhao; Meng-Sen Ma

    2014-01-01

    We study the equal area laws of d -dimensional RN-AdS black hole. We choose two kinds of phase diagrams, P-V and T-S . We employ the equal area laws to find an isobar which is the real two-phase coexistence line. Our calculation is much simpler to derive the critical value of the thermodynamic quantities. According to the thermodynamic quantities, we also study the latent heat of the black hole.

  18. Virial Theorem for Nonrelativistic Quantum Fields in id="M1" xmlns="http://www.w3.org/1998/Math/MathML">D Spatial Dimensions

    OpenAIRE

    Lin, Chris L.(Department of Physics, University of Houston, Houston, TX 77204-5005, USA); Ordóñez, Carlos R.

    2015-01-01

    The virial theorem for nonrelativistic complex fields in D spatial dimensions and with arbitrary many-body potential is derived, using path-integral methods and scaling arguments recently developed to analyze quantum anomalies in low-dimensional systems. The potential appearance of a Jacobian J due to a change of variables in the path-integral expression for the partition function of the system is pointed out, although in order to make contact with the literature most of the analysis deals wi...

  19. Searches for Prompt id="M1" xmlns="http://www.w3.org/1998/Math/MathML">R -Parity-Violating Supersymmetry at the LHC

    OpenAIRE

    Andreas Redelbach

    2015-01-01

    Searches for supersymmetry (SUSY) at the LHC frequently assume the conservation of R -parity in their design, optimization, and interpretation. In the case that R -parity is not conserved, constraints on SUSY particle masses tend to be weakened with respect to R -parity-conserving models. We review the current status of searches for R -parity-violating (RPV) supersymmetry models at the ATLAS and CMS experiments, limited to 8 TeV search results published or submitted for publicatio...

  20. id="M1" xmlns="http://www.w3.org/1998/Math/MathML">πe3 Form Factor id="M2" xmlns="http://www.w3.org/1998/Math/MathML">f- Near the Mass Shell

    OpenAIRE

    Krivoruchenko, M. I.

    2015-01-01

    The generalized Ward-Takahashi identity (gWTI) in the pion sector for broken isotopic symmetry is derived and used for the model-independent calculation of the longitudinal form factor f- of the πe3 vector vertex. The on-shell f- is found to be proportional to the mass difference of the pions and the difference between the vector isospin T=1 and scalar isospin T=2 pion radii. A numerical estimate of the form factor yields a value two times higher than the previous estimate from the quark mode...

  1. Spherically Symmetric Geometries in id="M1" xmlns="http://www.w3.org/1998/Math/MathML">f(T) and id="M2" xmlns="http://www.w3.org/1998/Math/MathML">f(R) Gravitational Theories

    OpenAIRE

    Gamal G. L. Nashed

    2015-01-01

    Using the well know relation between Ricci scalar, R , and torsion scalar, T , that is, R=-T-2∇αTα , we show that, for any spherically symmetric spacetime whose (i) scalar torsion vanishing, that is, T=TμναSαμν=0 or (ii) total derivative term, that is, ∇αTα with Tα is the contraction of the torsion, vanishing, or (iii) the combination of scalar torsion and total derivative term vanishing, could be solution for f(T) and f(R) gravitational theories.

  2. id="M1" xmlns="http://www.w3.org/1998/Math/MathML">BcBP, id="M2" xmlns="http://www.w3.org/1998/Math/MathML">BV Decays with the QCD Factorization Approach

    OpenAIRE

    Chang, Qin; Sun, Junfeng; Wang, Na; Yang, Yueling

    2015-01-01

    We studied the nonleptonic Bc→BP , BV decays with the QCD factorization approach. It is found that the Cabibbo favored processes of Bc→Bsπ , Bsρ , BuK- are the promising decay channels with branching ratio larger than 1%, which should be observed earlier by the LHCb collaboration.

  3. Study on the id="M1" xmlns="http://www.w3.org/1998/Math/MathML">Υ(1S) id="M2" xmlns="http://www.w3.org/1998/Math/MathML">BcM Weak Decays

    OpenAIRE

    Chang, Qin; Sun, Junfeng; Chen, Lili; Wang, Na; Huang, Jinshu; Yang, Yueling

    2015-01-01

    Motivated by the prospects of the potential Υ(1S) particle at high-luminosity heavy-flavor experiments, we studied the Υ(1S) →BcM weak decays, where M = π , ρ , K(∗) . The nonfactorizable contributions to hadronic matrix elements are taken into consideration with the QCDF approach. It is found that the CKM-favored Υ(1S) →Bcρ decay has branching ratio of O(10-10) , which might be measured promisingly by the future experiments.

  4. id="M1" xmlns="http://www.w3.org/1998/Math/MathML">Z Resonance and Associated id="M2" xmlns="http://www.w3.org/1998/Math/MathML">Zh Production at Future Higgs Boson Factory: ILC and CLIC

    OpenAIRE

    A. Gutiérrez-Rodríguez; Hernández-Ruíz, M. A.

    2015-01-01

    We study the prospects of the B-L model with an additional Z′ boson to be a Higgs boson factory at high-energy and high-luminosity linear electron positron colliders, such as the ILC and CLIC, through the Higgs-strahlung process e+e-→(Z,Z′)→Zh , including both the resonant and the nonresonant effects. We evaluate the total cross section of Zh and we calculate the total number of events for integrated luminosities of 500–2000 fb−1 and center of mass energies between 500 and 3000 GeV. We find t...

  5. Gluon Shadowing Effects on id="M1" xmlns="http://www.w3.org/1998/Math/MathML">J/ψ and id="M2" xmlns="http://www.w3.org/1998/Math/MathML">Υ Production in id="M3" xmlns="http://www.w3.org/1998/Math/MathML">p+Pb Collisions at id="M4" xmlns="http://www.w3.org/1998/Math/MathML">sNN=115  GeV and id="M5" xmlns="http://www.w3.org/1998/Math/MathML">Pb+p Collisions at id="M6" xmlns="http://www.w3.org/1998/Math/MathML">sNN=72  GeV at AFTER@LHC

    OpenAIRE

    R. Vogt

    2015-01-01

    We explore the effects of shadowing on inclusive J/ψ and Υ(1S) production at AFTER@LHC. We also present the rates as a function of pT and rapidity for p+Pb and Pb+p collisions in the proposed AFTER@LHC rapidity acceptance.

  6. Regulation of Active DNA Demethylation by a Methyl-CpG-Binding Domain Protein in Arabidopsis thaliana.

    Directory of Open Access Journals (Sweden)

    Qi Li

    2015-05-01

    Full Text Available Active DNA demethylation plays crucial roles in the regulation of gene expression in both plants and animals. In Arabidopsis thaliana, active DNA demethylation is initiated by the ROS1 subfamily of 5-methylcytosine-specific DNA glycosylases via a base excision repair mechanism. Recently, IDM1 and IDM2 were shown to be required for the recruitment of ROS1 to some of its target loci. However, the mechanism(s by which IDM1 is targeted to specific genomic loci remains to be determined. Affinity purification of IDM1- and IDM2- associating proteins demonstrated that IDM1 and IDM2 copurify together with two novel components, methyl-CpG-binding domain protein 7 (MBD7 and IDM2-like protein 1 (IDL1. IDL1 encodes an α-crystallin domain protein that shows high sequence similarity with IDM2. MBD7 interacts with IDM2 and IDL1 in vitro and in vivo and they form a protein complex associating with IDM1 in vivo. MBD7 directly binds to the target loci and is required for the H3K18 and H3K23 acetylation in planta. MBD7 dysfunction causes DNA hypermethylation and silencing of reporter genes and a subset of endogenous genes. Our results suggest that a histone acetyltransferase complex functions in active DNA demethylation and in suppression of gene silencing at some loci in Arabidopsis.

  7. 试论韩国《春香传》故事中青春与爱情的交响%A Preliminary Study into the Symphony of Youth and Love in the Korean Story Empress Chung

    Institute of Scientific and Technical Information of China (English)

    许建昆; 崔圭万

    2015-01-01

    Three versions of the Korean romance Empress Chung exist in Taiwan, namely Empress Chung in Chinese, the Shuishan edition of Guang Han Lou Ji, and a translation from the Chonju version of A Spring Festival Song by Liu Yingjiu. Considering the maturity of the story-line, Empress Chung in Chinese is the earliest version. All these versions were adapted from operas of different historical periods. However, the operas from various times evolved respectively from the performing art of Pansori. Therefore, Pansori is the true source of the opera and novel versions of Empress Chung. In stories emerged during the later periods, the academic circle focused more on the revolt against authority, the identity of the protagonist, the form of marriage and the chastity of women, while ignored the motif of dominant role of love. The paper discusses the literary genres and motif representations of various versions, and demonstrates that the core motif of Empress Chung should be an ode to youth and love.%就台湾所见韩国传奇小说《春香传》,有《汉文春香传》、水山《广寒楼记》本,以及柳应九依据全州完版本《烈女春香守节歌》的译本三种。从故事情节的成熟度而言,应以《汉文春香传》为最早。它们都是根据不同时代的戏剧形式而改编。然而,这些不同时代的戏剧,各自从盘骚里的表演艺术演化而成。所以说,盘骚里才是《春香传》戏曲与小说类型真正的源头。在越晚期发展的故事里,学界似乎强调反抗威权、主角身份、婚姻形式与女性贞节,反而忽略了爱情至上的母题。文章论述各种版本的文体类型与主题表现,证明歌咏青春与爱情才是《春香传》的核心母题。

  8. Looking for a Symphony: A Sort of Essay with a Perspective on Activity Theories and the Ontology of Psychology: Learning from Danish and Russian Experiences by Jens Mammen & Irina Mironenko.

    Science.gov (United States)

    Neumann, Asger

    2016-06-01

    As a perspective on Mammen and Miroenkos the article is reflecting on the possibility of Activity Theory being a foundation on which Psychology could be integrated. Mammen and Miroenkos point that directed activity not only is towards objects "defined as a sum of qualities, but by individual reference" is a starting point. As a specific example the phenomenon Love, as "significant object relations", is related to the concept "choice categories". It is stated that relations of affection and love can't be understood independent of history of common activity, and that this makes the concept "choice categories" central in a psychological understanding of what love is. PMID:26476531

  9. Unscrambling of Traditional Musical Culture Features in Contemporary Symphony Works%当代交响音乐作品的传统音乐文化特征解读

    Institute of Scientific and Technical Information of China (English)

    杨美嫒

    2006-01-01

    我国作曲家在同国际乐坛前卫的音乐潮流相接轨的同时并没有忘记作为一个华夏子孙应负有的弘扬中华民族优秀文化传统的责任,创作了许多具有中国传统音乐文化意蕴的作品.通过对当代一些交响音乐作品的解读,可以看到作曲家是怎样从传统文化、民间音乐、文人文化等领域中汲取养料,以体现民族精神、民族文化深刻内涵的.

  10. ECM. Kauneim heli pärast vaikust / Immo Mihkelson

    Index Scriptorium Estoniae

    Mihkelson, Immo, 1959-

    2007-01-01

    Uutest Saksa plaadifirma ECM heliplaatidest Frode Haltli "Passing Images", Roscoe Mitchell "The Transatlantic Art Ensemble Composition", Chritian Wallumrod "TRhe Zoo Is Far", Valentin Silvestrov "Symphony No. 6"

  11. Muusikamaailm / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    1999-01-01

    Sibeliuse kogutud teostest, Ashkenazy lahkumisest Lääne-Berliini Raadio Sümfooniaorkestri juurest, Natonal Symphony Orcestra kontsertidest Hiinas ja Jaapanis, Viini klassikutele orienteeritud kammerorkestri tegevusest

  12. Transverse Momentum Spectra of id="M1" xmlns="http://www.w3.org/1998/Math/MathML">KS0 and id="M2" xmlns="http://www.w3.org/1998/Math/MathML">K*0 at Midrapidity in id="M3" xmlns="http://www.w3.org/1998/Math/MathML">d + Au, Cu + Cu, and id="M4" xmlns="http://www.w3.org/1998/Math/MathML">p+p Collisions at id="M5" xmlns="http://www.w3.org/1998/Math/MathML">sNN=200  GeV

    OpenAIRE

    Bao-Chun Li; Guo-Xing Zhang; Yuan-Yuan Guo

    2015-01-01

    We analyze transverse momentum spectra of KS0 and K*0 at midrapidity in d + Au, Cu + Cu, and p+p collisions at sNN=200  GeV in the formworks of Tsallis statistics and Boltzmann statistics, respectively. Both of them can describe the transverse momentum spectra and extract the thermodynamics parameters of matter evolution in the collisions. The parameters are helpful for us to understand the thermodynamics factors of the particle production.

  13. A Human-Centred Approach to National Identity Management Systems

    OpenAIRE

    Pengiran Salleh Ab Rahaman, P. A.

    2012-01-01

    This thesis explores the concept of a human-centred Identity Management System (IDMS), and how it can be implemented by organisations. The review of the literature on previous approaches to identity (i.e. privacy, trust, and usability) reveals that claims of IDMS being ‘human-centred’ are rhetorical; in reality, organisations’ administrative convenience is prioritised over the needs of individuals who are treated as purely functional components within the IDMS ecosystem. The research conducte...

  14. Rheology enhancement for remediated PX6 melter feed

    International Nuclear Information System (INIS)

    This document is referenced in WSRC-TR-94-0556. This memorandum summarizes results of experimental work performed on the original IDMS PX6 melter feed, the remediated IDMS PX6 melter feed, and melter feeds produced in a laboratory simulation to duplicate the IDMS remediation as well as the experimental results on the caustic treatment to enhance the rheology. Characterization of the products of excess caustic addition and what steps to take if excess caustic is inadvertently added to the IDMS PX6 melter feed are also discussed

  15. Study of the id="M1" xmlns="http://www.w3.org/1998/Math/MathML">ψ(1S,2S) and id="M2" xmlns="http://www.w3.org/1998/Math/MathML">ηc(1S,2S) Weak Decays into id="M3" xmlns="http://www.w3.org/1998/Math/MathML">DM

    OpenAIRE

    Yang, Yueling; Sun, Junfeng; Huang, Jinshu; Chen, Lili; Chang, Qin

    2016-01-01

    Inspired by the recent measurements on the J/ψ(1S)→Dsρ , DuK⁎ weak decays at BESIII and the potential prospects of charmonium at high-luminosity heavy-flavor experiments, we study ψ(1S,2S) and ηc(1S,2S) weak decays into final states including one charmed meson plus one light meson, considering QCD corrections to hadronic matrix elements with QCD factorization approach. It is found that the Cabibbo-favored ψ(1S,2S)→Ds-ρ+ , Ds-π+ , D¯u0K¯⁎0 decays have large branching ratios ≳10-10 , which migh...

  16. Near-Threshold Production of id="M1" xmlns="http://www.w3.org/1998/Math/MathML">W± , id="M2" xmlns="http://www.w3.org/1998/Math/MathML">Z0 , and id="M3" xmlns="http://www.w3.org/1998/Math/MathML">H0 at a Fixed-Target Experiment at the Future Ultrahigh-Energy Proton Colliders

    OpenAIRE

    Lansberg, J. P; Mikkelsen, R.; Uggerhøj, U. I.

    2015-01-01

    We outline the opportunities to study the production of the Standard Model bosons, W± , Z0 , and H0 , at “low” energies at fixed-target experiments based on possible future ultrahigh-energy proton colliders, that is, the High-Energy LHC, the Super proton-proton Collider, and the Future Circular Collider hadron-hadron. These can be indeed made in conjunction with the proposed future colliders designed to reach up to s=100  TeV by using bent crystals to extract part of the halo of the beam whic...

  17. Rare id="M1" xmlns="http://www.w3.org/1998/Math/MathML">Bsγνν- Decay in Family Nonuniversal id="M2" xmlns="http://www.w3.org/1998/Math/MathML">Z Model

    OpenAIRE

    Şirvanlı, Berin Belma

    2015-01-01

    The rare Bs→γνν- decay with polarized photon is studied in the framework of a family nonuniversal Z′ model. The branching ratio and photon polarization asymmetry to the model parameters are calculated and compared with the Standard Model. Deviations from the Standard Model will indicate the presence of new physics.

  18. Information delivery manuals to facilitate it supported energy analysis

    DEFF Research Database (Denmark)

    Mondrup, Thomas Fænø; Karlshøj, Jan; Vestergaard, Flemming

    of information exchange and digital workflows is required. This paper presents the preliminary findings of an ongoing study aimed at developing an Information Delivery Manual (IDM) for IT supported energy analysis at concept design phase. The IDM development is based on: (1) a review of current approaches (2...

  19. Process and building information modelling in the construction industry by using information delivery manuals and model view definitions

    DEFF Research Database (Denmark)

    Karlshøj, Jan

    2012-01-01

    Part 1; and the Model View Definition (MVD) methodology developed by Buildingsmart and BLIS. The research also includes a review of concrete IDM development projects that have been developed over the last five years. Although the study has identified interest in the IDM methodology in a number of...... information and specifying exactly which objects and properties are needed for each process and which information is produced by the processes. The present study is based on reviewing the existing methodology of Information Delivery Manuals (IDM) from Buildingsmart, which also is also an ISO standard 29481....... The project-based approach is an obstacle to standardized processes and exchange requirements, which are vital elements in the methodology of making IDMs. Several of the proposed IDMs have been developed or sponsored by public clients that have a long-term perspective and the ability to push...

  20. Hermitian id="M1" xmlns="http://www.w3.org/1998/Math/MathML">(ϵ,δ) -Freudenthal-Kantor Triple Systems and Certain Applications of *-Generalized Jordan Triple Systems to Field Theory

    OpenAIRE

    Sato, Matsuo; Kamiya, Noriaki

    2014-01-01

    We define Hermitian (ϵ,δ) -Freudenthal-Kantor triple systems and prove a structure theorem. We also give some examples of triple systems that are generalizations of the u(N)⊕u(M) and sp(2N)⊕u(1) Hermitian 3-algebras. We apply a * -generalized Jordan triple system to a field theory and obtain a Chern-Simons gauge theory. We find that the novel Higgs mechanism works, where the Chern-Simons gauge theory reduces to a Yang-Mills theory in a certain limit.

  1. Spherically Symmetric Solution in (1+4)-Dimensional id="M1" xmlns="http://www.w3.org/1998/Math/MathML">f(T) Gravity Theories

    OpenAIRE

    2014-01-01

    A nondiagonal spherically symmetric tetrad field, involving four unknown functions of radial coordinate r plus an angle Φ , which is a generalization of the azimuthal angle ϕ , is applied to the field equations of (1+4)-dimensional f(T) gravity theory. A special vacuum solution with one constant of integration is derived. The physical meaning of this constant is shown to be related to the gravitational mass of the system and the associated metric represents Schwarzschild in (1+4)-dimension. T...

  2. Regularization of id="M1" xmlns="http://www.w3.org/1998/Math/MathML">f(T) Gravity Theories and Local Lorentz Transformation

    OpenAIRE

    Gamal G. L. Nashed

    2015-01-01

    We regularized the field equations of f(T) gravity theories such that the effect of local Lorentz transformation (LLT), in the case of spherical symmetry, is removed. A “general tetrad field,” with an arbitrary function of radial coordinate preserving spherical symmetry, is provided. We split that tetrad field into two matrices; the first represents a LLT, which contains an arbitrary function, and the second matrix represents a proper tetrad field which is a solution to the field equations of...

  3. New Estonian CDs / Igor Garshnek

    Index Scriptorium Estoniae

    Garšnek, Igor, 1958-

    2001-01-01

    Uutest heliplaatidest "Eesti portreed", Lepo Sumera. Film Music by Lepo Sumera, Urmas Sisask "Starry Sky Cycle", "Poeme d'amour", "Tango King Astor Piazolla", "Eduard Tubin. Complete Symphonies vol. 2", Henn Rebane "Arabesque", Eino Tamberg "Nocturne"

  4. Pop / Barbi Pilvre

    Index Scriptorium Estoniae

    Pilvre, Barbi, 1963-

    2007-01-01

    Heliplaatidest: Tokio Hotel "Zimmer 483", Air "Pocket Symphony", Mstrkrft "The Looks", Deerhoof "Friend Opportunity", 30 Seconds to Mars "A Beatiful Lie", Ferry "Dylanesque", Joss Stone "Introducing Joss Stone", Clint Mansell "The Fountain. Original soundtrack"

  5. Plaadid / Valner Valme

    Index Scriptorium Estoniae

    Valme, Valner, 1970-

    2002-01-01

    Uutest plaatidest Craig David "Slicker Than Your Avarage", Whitney Houston "Just Whitney", Christina Aguilera "Stripped", Shaggy "Lucky Day", Tolga Kashif "The Queen Symphony", Mark Knopfler "Ragpicker's Dream", Soul Milita "On The Rise", Vello Orumets "Sõbrale"

  6. Kuula. Pariisist Tokiosse, diivanilt tõusmata / Mart Juur

    Index Scriptorium Estoniae

    Juur, Mart, 1964-

    2007-01-01

    Heliplaatidest: Ozzy Osbourne "The Essential", Art Garfunkel "Some Enchanted Evening", Richard Galliano "Luz Negra", Music From Motion Picture "Dreamgirls", "Blue Note Trip Jazzanova", Mika "Life in Cartoon Motion". Prantsuse elektroonilise muusika ansamblist Air, heliplaadist "Pocket Symphony"

  7. Easing Joint Pain: Are NSAIDs Right for You?

    Medline Plus

    Full Text Available ... the other drugs, and they cost less. The dollar symbol  means the dose of that drug may ... prices for March 2013, rounded to the nearest dollar. Data provided by Symphony Health Solutions, which is ...

  8. Pop / Siim Nestor

    Index Scriptorium Estoniae

    Nestor, Siim, 1974-

    2008-01-01

    Heliplaatidest: Supergrass "Diamond Hoo Ha", Man In Maardu "Solid Symphonies", Van Der Graaf Generator "Trisector", Bon Iver "For Emma, Forever Ago", The Last Shadow Puppets "The Age Of The Understatement", Brad Mehldau Trio "Live", Mariah Carey "E=MCø"

  9. Easing Joint Pain: Are NSAIDs Right for You?

    Medline Plus

    Full Text Available ... based on a scientific review by the Oregon Health and Science University-based Drug Effectiveness Review Project. ... to the nearest dollar. Data provided by Symphony Health Solutions, which is not involved in our analysis ...

  10. Fantasievoll / Giselher Schubert

    Index Scriptorium Estoniae

    Schubert, Giselher

    2008-01-01

    Arvustus: Kristjan Järvi. Symphony Orchestra of Norrlands Opera. To the new world and beyond. Igor Stravinsky / Paul Hindemith. Diepholz (Germany) : CCn'C, 2006. Heliplaadil dirigeerib Kristjan Järvi

  11. Silja myrskyn keskellä / Petri Koskinen

    Index Scriptorium Estoniae

    Koskinen, Petri

    2007-01-01

    Silja Line tegevjuht Keijo Mehtonen kommenteerib Tallinki juhtide käitumist Silja Symphony pardal, Rootsi ametiühingu SEKO kahjutasu nõudeid, Silja ja Tallinki organisatsioonikultuuri erinevusi ja Tallinki edu põhjuseid

  12. International Marketing Plan of International Sibelius Festival 2015

    OpenAIRE

    Räty, Jessica

    2013-01-01

    The purpose of this research was to help prepare an international marketing plan for Lahti Symphony Orchestra’s International Sibelius Festival 2015. To achieve this, the research examines marketing of events and marketing planning reflecting it to classical music festivals. The research objective was to gain knowledge from marketing of classical music festivals, and based on that, to create priming international marketing plan for Lahti Symphony Orchestra’s International Sibelius Festiva...

  13. Pulsed power supply system of magnetic field coils of ion diode

    International Nuclear Information System (INIS)

    The pulsed power system of magnetic coils of an ion diode with external magnetic insulation (IDM), which ensures operation of the diode in the frequency mode, is described. Demands are formulated for the IDM magnetic field in which the electronic cloud acting as a cathode in the diode is formed as well as for storage conditions of the negative charge in the magnetic field for neutralizing the ion beam in the ion-beam drift area. The basic relationships required for engineering calculations of the IDM coils and a pulsed power system in the frequency mode are given

  14. 众语喧哗时代的平民化“交响乐”——解读电影《辛亥革命》%Symphony of Populace in a Multi-lingua Clamorous Era——An interpretation of the film Revolution of 1911

    Institute of Scientific and Technical Information of China (English)

    王淑娅

    2012-01-01

    The film "Revolution of 1911",produced to celebrate the 100th anniversary o f the revolution by the same name,has exhibited some changes in the ways tradit ionally applied in producing the theme films:ideology being weakened,the narra tive perspective being minor but significant and representative enough,and aest hetic weight being plurally balanced.All this shows that the microscopic ideolog y and historical concepts embodied in the theme films in China reveal an tendenc y of progress.%为纪念辛亥革命100周年而拍摄的电影《辛亥革命》,—改传统主旋律电影的套路,意识形态日趋淡化,叙事视角以小见大,审美权重多元均衡。这表明,我国主旋律电影其宏观意识形态和历史观点一直呈现出进步的态势。

  15. Celebrations Marking the 50th Anniversary of the China Junior Symphony Orchestra and the Young Pioneers Band Held in Beijing%永远年轻的乐团——中国少年交响乐团暨"红领巾乐队"成立50周年庆典活动在京举行

    Institute of Scientific and Technical Information of China (English)

    宋歌

    2010-01-01

    @@ 在金秋送爽的大好时节,全国人民还沉浸在建国60周年的喜庆气氛里,中央音乐学院附中中国少年交响乐团暨"红领巾乐队"迎来了50周岁的生日02009年10月15日、16日,中央音乐学院附中分别举办了中国少年交响乐团暨"红领巾乐队"成立50周年庆典音乐会和座谈会,以此来纪念和庆贺这个美好的日子.

  16. Centaure: an heterogeneous parallel architecture for computer vision

    International Nuclear Information System (INIS)

    This dissertation deals with the architecture of parallel computers dedicated to computer vision. In the first chapter, the problem to be solved is presented, as well as the architecture of the Sympati and Symphonie computers, on which this work is based. The second chapter is about the state of the art of computers and integrated processors that can execute computer vision and image processing codes. The third chapter contains a description of the architecture of Centaure. It has an heterogeneous structure: it is composed of a multiprocessor system based on Analog Devices ADSP21060 Sharc digital signal processor, and of a set of Symphonie computers working in a multi-SIMD fashion. Centaure also has a modular structure. Its basic node is composed of one Symphonie computer, tightly coupled to a Sharc thanks to a dual ported memory. The nodes of Centaure are linked together by the Sharc communication links. The last chapter deals with a performance validation of Centaure. The execution times on Symphonie and on Centaure of a benchmark which is typical of industrial vision, are presented and compared. In the first place, these results show that the basic node of Centaure allows a faster execution than Symphonie, and that increasing the size of the tested computer leads to a better speed-up with Centaure than with Symphonie. In the second place, these results validate the choice of running the low level structure of Centaure in a multi- SIMD fashion. (author)

  17. Syndrome coronarien aigu en post-partum secondaire à une dissection coronaire spontanée: à propos d'un cas

    OpenAIRE

    El Malki Berrada, Nabil; Zaimi, Achraf; Ezzouak, Abdellatif; Belhachmi, Hassan; Lagziri, Alaeeddine; Ratbi, Sara; eddine Elyounassi, Badre

    2015-01-01

    L'IDM per gravidique est une complication grave qui entraine une morbidité et une mortalité maternelle élevée. Bien que l'athérosclérose soit la cause d'IDM la plus fréquente dans la population générale, elle n'est observée que chez un tiers des femmes enceintes. Chez ces dernières, la cause la plus fréquente d'IDM était la dissection coronaire. Nous rapportons l'observation clinique d'une jeune femme de 24 ans, sans facteur de risque cardiovasculaire, qui a présenté un IDM antérieur étendu 1...

  18. An Investigation of Challenges to Online Federated Identity Management Systems

    Directory of Open Access Journals (Sweden)

    Aparajita Pandey

    2012-04-01

    Full Text Available National and global economic, governmental and social activities now rely more and more on the Internet. Online Identity Management (IdM is a crucial component of those activities. Today, organisations in both the public and private sectors vary significantly in their approaches to IdM, devising their own means for establishing, verifying, storing and using digital identities over their networks and the Internet. Thus, the lack of common policies and approaches to such Federated IdM systems creates privacy, security and productivity issues in the increasingly interconnected economies, and hampers the ability of organisations to provide users with convenient services. This paper presents the investigation and discussion of challenges faced in implementing the Federated IdM in the online system. Also, a trust-based framework is discussed in order to combat these challenges.

  19. The Electroweak Phase Transition in the Inert Doublet Model

    CERN Document Server

    Blinov, Nikita; Stefaniak, Tim

    2015-01-01

    We study the strength of a first-order electroweak phase transition in the Inert Doublet Model (IDM), where particle dark matter (DM) is comprised of the lightest neutral inert Higgs boson. We improve over previous studies in the description and treatment of the finite-temperature effective potential and of the electroweak phase transition. We focus on a set of benchmark models inspired by the key mechanisms in the IDM leading to a viable dark matter particle candidate, and illustrate how to enhance the strength of the electroweak phase transition by adjusting the masses of the yet undiscovered IDM Higgs states. We argue that across a variety of DM masses, obtaining a strong enough first-order phase transition is a generic possibility in the IDM. We find that due to direct dark matter searches and collider constraints, a sufficiently strong transition and a thermal relic density matching the universal DM abundance is possible only in the Higgs funnel regime.

  20. The electroweak phase transition in the Inert Doublet Model

    Energy Technology Data Exchange (ETDEWEB)

    Blinov, Nikita [Department of Physics, University of California Santa Cruz,1156 High St, Santa Cruz, CA 95064 (United States); Santa Cruz Institute for Particle Physics,1156 High St, Santa Cruz, CA 95064 (United States); Theory Department, TRIUMF,4004 Wesbrook Mall, Vancouver, BC V6T 2A3 (Canada); Department of Physics and Astronomy, University of British Columbia,Vancouver, BC V6T 1Z1 (Canada); Profumo, Stefano; Stefaniak, Tim [Department of Physics, University of California Santa Cruz,1156 High St, Santa Cruz, CA 95064 (United States); Santa Cruz Institute for Particle Physics,1156 High St, Santa Cruz, CA 95064 (United States)

    2015-07-21

    We study the strength of a first-order electroweak phase transition in the Inert Doublet Model (IDM), where particle dark matter (DM) is comprised of the lightest neutral inert Higgs boson. We improve over previous studies in the description and treatment of the finite-temperature effective potential and of the electroweak phase transition. We focus on a set of benchmark models inspired by the key mechanisms in the IDM leading to a viable dark matter particle candidate, and illustrate how to enhance the strength of the electroweak phase transition by adjusting the masses of the yet undiscovered IDM Higgs states. We argue that across a variety of DM masses, obtaining a strong enough first-order phase transition is a generic possibility in the IDM. We find that due to direct dark matter searches and collider constraints, a sufficiently strong transition and a thermal relic density matching the universal DM abundance is possible only in the Higgs funnel regime.

  1. Simultaneous Determination of Selected B Vitamins in the NIST SRM 3280 Multivitamin/Multielement Tablets by Liquid Chromatography Isotope Dilution Mass Spectrometry

    Science.gov (United States)

    There is increased interest in accurately assessing the total dietary intake of vitamins from all sources, including foods and dietary supplements. Isotope dilution mass spectrometry (IDMS) can be a definitive analytical method for very accurate concentration determinations. A liquid chromatographic...

  2. Morbidity and mortality amongst infants of diabetic mothers admitted into a special care baby unit in Port Harcourt, Nigeria

    Directory of Open Access Journals (Sweden)

    Onubogu Uche C

    2010-12-01

    Full Text Available Abstract Background Infants born to diabetic women have certain distinctive characteristics, including large size and high morbidity risks. The neonatal mortality rate is over five times that of infants of non diabetic mothers and is higher at all gestational ages and birth weight for gestational age (GA categories. The study aimed to determine morbidity and mortality pattern amongst infants of diabetic mothers (IDMS admitted into the Special Care Baby Unit of University of Port Harcourt Teaching Hospital. Methods This was a study of prevalence of morbidity and mortality among IDMs carried out prospectively over a two year period. All IDMs (pregestational and gestational admitted into the Unit within the period were recruited into the study. Data on delivery mode, GA, birth weight, other associated morbidities, investigation results, treatment, duration of hospital stay and outcome were collated and compared with those of infants of non diabetic mothers matched for GA and birth weight admitted within the same period. Maternal data were reviewed retrospectively. Data were analyzed using SPSS 16.0. Results Sixty percent of the IDMs were born to mothers with gestational diabetes, while 40% were born to mothers with pregestational DM. 38 (74.3% were born by Caesarian section (CS, of which 20 (52.6% were by emergency CS. There was no significant difference in emergency CS rates, when compared with controls, but non-IDMs were more likely to be delivered vaginally. The mean GA of IDMs was 37.84 weeks ± 1.88. 29 (61.7% of them were macrosomic. The commonest morbidities were Hypoglycemia (significantly higher in IDMs than non-IDMs and hyperbilirubinaemia in 30 (63.8% and 26 (57.4% respectively. There was no difference in morbidity pattern between infants of pre- gestational and gestational diabetic mothers. Mortality rate was not significantly higher in IDMs Conclusions The incidence of macrosomia in IDMs was high but high rates of emergency CS was not

  3. Influence of pH and method of crystallization on the solid physical form of indomethacin.

    Science.gov (United States)

    Dubbini, Alessandra; Censi, Roberta; Martena, Valentina; Hoti, Ela; Ricciutelli, Massimo; Malaj, Ledjan; Di Martino, Piera

    2014-10-01

    The purpose of this study was to investigate the effect of pH and method of crystallization on the solid physical form of indomethacin (IDM). IDM, a non steroidal anti-inflammatory drug poorly soluble in water, underwent two different crystallization methods: crystallization by solvent evaporation under reduced pressure at 50.0°C (method A), and crystallization by cooling of solution from 50.0 to 5.0°C (method B). In both cases, several aqueous ethanolic solutions of IDM of different pHs were prepared. pHs were adjusted by adding acidic solutions (HCl 2M) or alkali (NaOH or NH4OH 2M) to an aqueous ethanolic solution of IDM. Thus, several batches were recovered after crystallization. The chemical stability of IDM was verified through (1)H NMR and mass spectroscopy (FIA-ESI-MS), that revealed that IDM degraded in strong alkali media (pH ≥ 12). Crystals obtained under different crystallization conditions at pHs of 1.0, 4.5, 7.0, 8.0, 10.0 and chemically stable were thus characterized for crystal habit by scanning electron microscopy, for thermal behaviour by differential scanning calorimetry, and thermogravimetry, and for solid state by X-ray powder diffractometry. Under the Method A, IDM always crystallized into pure metastable alpha form when solutions were acidified or alkalized respectively with HCl and NH4OH. On the contrary, in presence of NaOH, IDM crystallized under a mixture of alpha and sodium trihydrate form, because the presence of the sodium counter ion orientates the crystallization towards the formation of the trihydrate salt. Under the method B, at pH of 1.0, IDM crystallized under the alpha form; at pH 4.5, IDM crystallized under the form alpha in presence of some nuclei of gamma form; at pH 7.0, 8.0, and 10.0 for NH4OH, IDM crystallized under the most stable polymorph gamma form, whereas in presence of NaOH, a mix of alpha, and salt forms was formed whatever the pH of the solution. PMID:25064728

  4. Accurate determination of sulfur in gasoline and related fuel samples using isotope dilution ICP-MS with direct sample injection and microwave-assisted digestion

    Energy Technology Data Exchange (ETDEWEB)

    Heilmann, Jens; Boulyga, Sergei F.; Heumann, Klaus G. [Johannes Gutenberg-University, Institute of Inorganic Chemistry and Analytical Chemistry, Mainz (Germany)

    2004-09-01

    Inductively coupled plasma isotope-dilution mass spectrometry (ICP-IDMS) with direct injection of isotope-diluted samples into the plasma, using a direct injection high-efficiency nebulizer (DIHEN), was applied for accurate sulfur determinations in sulfur-free premium gasoline, gas oil, diesel fuel, and heating oil. For direct injection a micro-emulsion consisting of the corresponding organic sample and an aqueous {sup 34}S-enriched spike solution with additions of tetrahydronaphthalene and Triton X-100, was prepared. The ICP-MS parameters were optimized with respect to high sulfur ion intensities, low mass-bias values, and high precision of {sup 32}S/{sup 34}S ratio measurements. For validation of the DIHEN-ICP-IDMS method two certified gas oil reference materials (BCR 107 and BCR 672) were analyzed. For comparison a wet-chemical ICP-IDMS method was applied with microwave-assisted digestion using decomposition of samples in a closed quartz vessel inserted into a normal microwave system. The results from both ICP-IDMS methods agree well with the certified values of the reference materials and also with each other for analyses of other samples. However, the standard deviation of DIHEN-ICP-IDMS was about a factor of two higher (5-6% RSD at concentration levels above 100 {mu}g g{sup -1}) compared with those of wet-chemical ICP-IDMS, mainly due to inhomogeneities of the micro-emulsion, which causes additional plasma instabilities. Detection limits of 4 and 18 {mu}g g{sup -1} were obtained for ICP-IDMS in connection with microwave-assisted digestion and DIHEN-ICP-IDMS, respectively, with a sulfur background of the used Milli-Q water as the main limiting factor for both methods. (orig.)

  5. Development of a multi-species method by GC-coupling with inductively coupled plasma isotope dilution mass spectrometry for the simultaneous determination of alkylated lead, mercury and tin compounds

    OpenAIRE

    Poperechna, Nataliya

    2005-01-01

    An accurate and sensitive species-specific GC-ICP-IDMS (gas chromatography inductively coupled plasma isotope dilution mass spectrometry) method for the determination of trimethyllead and a multi-species-specific GC-ICP-IDMS method for the simultaneous determination of trimethyllead, methylmercury, and butyltins in biological and environmental samples were developed. They allow the determination of corresponding elemental species down to the low ng g-1 range. The developed synthesis scheme fo...

  6. Simulation of Populations in a Time-, Age- and Duration Dependent Illness-Death Model

    OpenAIRE

    Brinks, Ralph

    2012-01-01

    Relevant events in a three state illness-death model (IDM) of a chronic disease are the diagnosis of the disease and death with or without the disease. In this article a simulation framework for populations moving in the IDM is presented. The simulation is closely related to the concept of Lexis diagrams in event history analysis. Details of the implementation and an example of a hypothetical disease are described.

  7. COMBINE 2 seminar

    DEFF Research Database (Denmark)

    Sørensen, Lars Schiøtt; Jacobsen, Kim

    1995-01-01

    A seminar about the COMBINE project was described. Further, the project was described in generel, i.e. the COMBINE´s data model (IDM), the data exchange system (DES) and the different I/O-systems included in COMBINE 2......A seminar about the COMBINE project was described. Further, the project was described in generel, i.e. the COMBINE´s data model (IDM), the data exchange system (DES) and the different I/O-systems included in COMBINE 2...

  8. Explicit Memory Performance in Infants of Diabetic Mothers at 1 Year of Age

    OpenAIRE

    DeBoer, Tracy; Wewerka, Sandi; Bauer, Patricia J.; Georgieff, Michael K.; Nelson, Charles A.

    2005-01-01

    The aim of the present research was to investigate the impact of abnormal fetal environment on explicit memory performance. Based on animal models, it was hypothesized that infants of diabetic mothers (IDMs) experience perturbations in memory performance due to exposure to multiple neurologic risk factors including: chronic hypoxia, hyperglycemia/reactive hypoglycemia, and iron deficiency. Memory performance, as measured by the elicited/deferred imitation paradigm, was compared between 13 IDM...

  9. Seeding supermassive black holes with a non-vortical dark-matter subcomponent

    OpenAIRE

    Sawicki, Ignacy; Marra, Valerio; Valkenburg, Wessel

    2013-01-01

    A perfect irrotational fluid with the equation of state of dust, Irrotational Dark Matter (IDM), is incapable of virializing and instead forms a cosmoskeleton of filaments with supermassive black holes at the joints. This stark difference from the standard cold dark matter (CDM) scenario arises because IDM must exhibit potential flow at all times, preventing shell-crossing from occurring. This scenario is applicable to general non-oscillating scalar-field theories with a small sound speed. Ou...

  10. Status of the Inert Doublet Model and the role of multileptons at the LHC

    International Nuclear Information System (INIS)

    A possible feature of the Inert Doublet Model (IDM) is to provide a dark matter candidate together with an alteration of both direct and indirect collider constraints that allow for a heavy Higgs boson. We study the IDM in light of recent results from Higgs searches at the Large Hadron Collider (LHC) in combination with dark matter direct-detection limits from the XENON experiment. We ask under what conditions the IDM can still accommodate a heavy Higgs boson. We find that IDM scenarios with a Higgs boson in the mass range 160 to 600 GeV are ruled out only when all experimental constraints are combined. For models explaining only a fraction of the DM the limits are weakened, and IDMs with a heavy Higgs are allowed. We discuss the prospects for future detection of such IDM scenarios in the four-lepton plus missing energy channel at the LHC. This signal can show up in the first year of running at √(s)=14 TeV, and we present detector-level studies for a few benchmark models. (orig.)

  11. Status of the Inert Doublet Model and the role of multileptons at the LHC

    Energy Technology Data Exchange (ETDEWEB)

    Gustafsson, Michael [Univ. Libre de Bruxelles (Belgium). Service de Physique Theorique; Rydbeck, Sara [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Lopez-Honorez, Laura [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); Lundstroem, Erik [AlbaNova Univ., Stockholm (Sweden). The Oskar Klein Centre

    2012-06-15

    A possible feature of the Inert Doublet Model (IDM) is to provide a dark matter candidate together with an alteration of both direct and indirect collider constraints that allow for a heavy Higgs boson. We study the IDM in light of recent results from Higgs searches at the Large Hadron Collider (LHC) in combination with dark matter direct-detection limits from the XENON experiment. We ask under what conditions the IDM can still accommodate a heavy Higgs boson. We find that IDM scenarios with a Higgs boson in the mass range 160 to 600 GeV are ruled out only when all experimental constraints are combined. For models explaining only a fraction of the DM the limits are weakened, and IDMs with a heavy Higgs are allowed. We discuss the prospects for future detection of such IDM scenarios in the four-lepton plus missing energy channel at the LHC. This signal can show up in the first year of running at {radical}(s)=14 TeV, and we present detector-level studies for a few benchmark models. (orig.)

  12. Evaluation of matrix effect in isotope dilution mass spectrometry based on quantitative analysis of chloramphenicol residues in milk powder

    International Nuclear Information System (INIS)

    Graphical abstract: -- Highlights: •We develop a strategy to evaluate matrix effect and its impact on the IDMS results. •Matrix effect and IDMS correction factor from different conditions are evaluated. •Ion suppression effect is observed in LLE and HLB pre-treated sample solutions. •Ion enhancement effect is found in MCX pre-treated sample solution. •IDMS correction factor in HLB and MCX solutions in three instruments is close to 1 -- Abstract: In the present study, we developed a comprehensive strategy to evaluate matrix effect (ME) and its impact on the results of isotope dilution mass spectrometry (IDMS) in analysis of chloramphenicol (CAP) residues in milk powder. Stable isotope-labeled internal standards do not always compensate ME, which brings the variation of the ratio (the peak area of analyte/the peak area of isotope). In our investigation, impact factors of this variation were studied in the extraction solution of milk powder using three mass spectrometers coupled with different ion source designs, and deuterium-labeled chloramphenicol (D5-CAP) was used as the internal standard. ME from mobile phases, sample solvents, pre-treatment methods, sample origins and instruments was evaluated, and its impact on the results of IDMS was assessed using the IDMS correction factor (θ). Our data showed that the impact of ME of mobile phase on the correction factor was significantly greater than that of sample solvent. Significant ion suppression and enhancement effects were observed in different pre-treated sample solutions. The IDMS correction factor in liquid–liquid extraction (LLE) and molecular imprinted polymer (MIP) extract with different instruments was greater or less 1.0, and the IDMS correction factor in hydrophilic lipophilic balance (HLB) and mix-mode cation exchange (MCX) extract with different instruments was all close to 1.0. To the instrument coupled with different ion source design, the impact of ME on IDMS quantitative results was

  13. Comparison of GC-ICP-MS and HPLC-ICP-MS for species-specific isotope dilution analysis of tributyltin in sediment after accelerated solvent extraction

    International Nuclear Information System (INIS)

    This study describes a direct comparison of GC and HPLC hyphenated to ICP-MS determination of tributyltin (TBT) in sediment by species-specific isotope dilution analysis (SS-IDMS). The certified reference sediment PACS-2 (NRC, Canada) and a candidate reference sediment (P-18/HIPA-1) were extracted using an accelerated solvent extraction (ASE) procedure. For comparison of GC and LC methods an older bottle of PACS-2 was used, whilst a fresh bottle was taken for demonstration of the accuracy of the methods. The data obtained show good agreement between both methods for both the PACS-2 sediment (LC-ICP-IDMS 828±87 ng g-1 TBT as Sn, GC-ICP-IDMS 848±39 ng g-1 TBT as Sn) and the P-18/ HIPA-1 sediment (LC-ICP-IDMS 78.0±9.7 ng g-1 TBT as Sn, GC-ICP-IDMS 79.2±3.8 ng g-1 TBT as Sn). The analysis by GC-ICP-IDMS offers a greater signal-to-noise ratio and hence a superior detection limit of 0.03 pg TBT as Sn, in the sediment extracts compared to HPLC-ICP-IDMS (3 pg TBT as Sn). A comparison of the uncertainties associated with both methods indicates superior precision of the GC approach. This is related to the better reproducibility of the peak integration, which affects the isotope ratio measurements used for IDMS. The accuracy of the ASE method combined with HPLC-ICP-IDMS was demonstrated during the international interlaboratory comparison P-18 organised by the Comite Consultatif pour la Quantite de Matiere (CCQM). The results obtained by GC-ICP-IDMS for a newly opened bottle of PACS-2 were 1087±77 ng g-1 Sn for DBT and 876±51 ng g-1 Sn for TBT (expanded uncertainties with a coverage factor of 2), which are in good agreement with the certified values of 1090±150 ng g-1 Sn and 980±130 ng g-1 Sn, respectively. (orig.)

  14. Comparison of GC-ICP-MS and HPLC-ICP-MS for species-specific isotope dilution analysis of tributyltin in sediment after accelerated solvent extraction

    Energy Technology Data Exchange (ETDEWEB)

    Wahlen, Raimund; Wolff-Briche, Celine [LGC Limited, Queens Road, TW11 0LY, Teddington, Middlesex (United Kingdom)

    2003-09-01

    This study describes a direct comparison of GC and HPLC hyphenated to ICP-MS determination of tributyltin (TBT) in sediment by species-specific isotope dilution analysis (SS-IDMS). The certified reference sediment PACS-2 (NRC, Canada) and a candidate reference sediment (P-18/HIPA-1) were extracted using an accelerated solvent extraction (ASE) procedure. For comparison of GC and LC methods an older bottle of PACS-2 was used, whilst a fresh bottle was taken for demonstration of the accuracy of the methods. The data obtained show good agreement between both methods for both the PACS-2 sediment (LC-ICP-IDMS 828{+-}87 ng g{sup -1} TBT as Sn, GC-ICP-IDMS 848{+-}39 ng g{sup -1} TBT as Sn) and the P-18/ HIPA-1 sediment (LC-ICP-IDMS 78.0{+-}9.7 ng g{sup -1} TBT as Sn, GC-ICP-IDMS 79.2{+-}3.8 ng g{sup -1} TBT as Sn). The analysis by GC-ICP-IDMS offers a greater signal-to-noise ratio and hence a superior detection limit of 0.03 pg TBT as Sn, in the sediment extracts compared to HPLC-ICP-IDMS (3 pg TBT as Sn). A comparison of the uncertainties associated with both methods indicates superior precision of the GC approach. This is related to the better reproducibility of the peak integration, which affects the isotope ratio measurements used for IDMS. The accuracy of the ASE method combined with HPLC-ICP-IDMS was demonstrated during the international interlaboratory comparison P-18 organised by the Comite Consultatif pour la Quantite de Matiere (CCQM). The results obtained by GC-ICP-IDMS for a newly opened bottle of PACS-2 were 1087{+-}77 ng g{sup -1} Sn for DBT and 876{+-}51 ng g{sup -1} Sn for TBT (expanded uncertainties with a coverage factor of 2), which are in good agreement with the certified values of 1090{+-}150 ng g{sup -1} Sn and 980{+-}130 ng g{sup -1} Sn, respectively. (orig.)

  15. Comparison of GC-ICP-MS and HPLC-ICP-MS for species-specific isotope dilution analysis of tributyltin in sediment after accelerated solvent extraction.

    Science.gov (United States)

    Wahlen, Raimund; Wolff-Briche, Céline

    2003-09-01

    This study describes a direct comparison of GC and HPLC hyphenated to ICP-MS determination of tributyltin (TBT) in sediment by species-specific isotope dilution analysis (SS-IDMS). The certified reference sediment PACS-2 (NRC, Canada) and a candidate reference sediment (P-18/HIPA-1) were extracted using an accelerated solvent extraction (ASE) procedure. For comparison of GC and LC methods an older bottle of PACS-2 was used, whilst a fresh bottle was taken for demonstration of the accuracy of the methods. The data obtained show good agreement between both methods for both the PACS-2 sediment (LC-ICP-IDMS 828+/-87 ng g(-1) TBT as Sn, GC-ICP-IDMS 848+/-39 ng g(-1) TBT as Sn) and the P-18/ HIPA-1 sediment (LC-ICP-IDMS 78.0+/-9.7 ng g(-1) TBT as Sn, GC-ICP-IDMS 79.2+/-3.8 ng g(-1) TBT as Sn). The analysis by GC-ICP-IDMS offers a greater signal-to-noise ratio and hence a superior detection limit of 0.03 pg TBT as Sn, in the sediment extracts compared to HPLC-ICP-IDMS (3 pg TBT as Sn). A comparison of the uncertainties associated with both methods indicates superior precision of the GC approach. This is related to the better reproducibility of the peak integration, which affects the isotope ratio measurements used for IDMS. The accuracy of the ASE method combined with HPLC-ICP-IDMS was demonstrated during the international interlaboratory comparison P-18 organised by the Comité Consultatif pour la Quantité de Matière (CCQM). The results obtained by GC-ICP-IDMS for a newly opened bottle of PACS-2 were 1087+/-77 ng g(-1) Sn for DBT and 876+/-51 ng g(-1) Sn for TBT (expanded uncertainties with a coverage factor of 2), which are in good agreement with the certified values of 1090+/-150 ng g(-1) Sn and 980+/-130 ng g(-1) Sn, respectively. PMID:12879193

  16. Evaluation of matrix effect in isotope dilution mass spectrometry based on quantitative analysis of chloramphenicol residues in milk powder

    Energy Technology Data Exchange (ETDEWEB)

    Li, Xiu Qin; Yang, Zong; Zhang, Qing He, E-mail: qhzhang204@gmail.com; Li, Hong Mei

    2014-01-07

    Graphical abstract: -- Highlights: •We develop a strategy to evaluate matrix effect and its impact on the IDMS results. •Matrix effect and IDMS correction factor from different conditions are evaluated. •Ion suppression effect is observed in LLE and HLB pre-treated sample solutions. •Ion enhancement effect is found in MCX pre-treated sample solution. •IDMS correction factor in HLB and MCX solutions in three instruments is close to 1 -- Abstract: In the present study, we developed a comprehensive strategy to evaluate matrix effect (ME) and its impact on the results of isotope dilution mass spectrometry (IDMS) in analysis of chloramphenicol (CAP) residues in milk powder. Stable isotope-labeled internal standards do not always compensate ME, which brings the variation of the ratio (the peak area of analyte/the peak area of isotope). In our investigation, impact factors of this variation were studied in the extraction solution of milk powder using three mass spectrometers coupled with different ion source designs, and deuterium-labeled chloramphenicol (D5-CAP) was used as the internal standard. ME from mobile phases, sample solvents, pre-treatment methods, sample origins and instruments was evaluated, and its impact on the results of IDMS was assessed using the IDMS correction factor (θ). Our data showed that the impact of ME of mobile phase on the correction factor was significantly greater than that of sample solvent. Significant ion suppression and enhancement effects were observed in different pre-treated sample solutions. The IDMS correction factor in liquid–liquid extraction (LLE) and molecular imprinted polymer (MIP) extract with different instruments was greater or less 1.0, and the IDMS correction factor in hydrophilic lipophilic balance (HLB) and mix-mode cation exchange (MCX) extract with different instruments was all close to 1.0. To the instrument coupled with different ion source design, the impact of ME on IDMS quantitative results was

  17. The Research of Car-Following Model Based on Real-Time Maximum Deceleration

    Directory of Open Access Journals (Sweden)

    Longhai Yang

    2015-01-01

    Full Text Available This paper is concerned with the effect of real-time maximum deceleration in car-following. The real-time maximum acceleration is estimated with vehicle dynamics. It is known that an intelligent driver model (IDM can control adaptive cruise control (ACC well. The disadvantages of IDM at high and constant speed are analyzed. A new car-following model which is applied to ACC is established accordingly to modify the desired minimum gap and structure of the IDM. We simulated the new car-following model and IDM under two different kinds of road conditions. In the first, the vehicles drive on a single road, taking dry asphalt road as the example in this paper. In the second, vehicles drive onto a different road, and this paper analyzed the situation in which vehicles drive from a dry asphalt road onto an icy road. From the simulation, we found that the new car-following model can not only ensure driving security and comfort but also control the steady driving of the vehicle with a smaller time headway than IDM.

  18. [Antibody detection after antepartal rhesus prophylaxis: normal values or sensitization].

    Science.gov (United States)

    Behrens, O; Bader, W; Holle, W; Maas, D H; Schneider, J

    1993-05-01

    Antibody screening tests were performed in 29 unsensitized pregnant women after antepartum Rh immune prophylaxis, using the indirect Coombs test (ICT) and a more sensitive ID-microtyping-system (IDM). With the ICT, anti-D antibodies were detected in 85% for at least 4 weeks and at most 8 weeks after immunisation. The maximum titer was 1:8. With the IDM, 97% showed antibodies against 'D' for at least 4 weeks and at most 11 weeks with a maximum of 1:16. The IDM titer was always 1 to 3 steps more sensitive than the ICT. After postpartum Rh immune prophylaxis, anti-D titers were again positive in many of the patients (ICT: 42%; IDM: 60%). In conclusion, it is nearly always possible to measure antibodies against 'D' after antepartum Rh immune prophylaxis and IDM was superior in comparison to ICT. However, maternal isoimmunisation to the rhesus antigen cannot be excluded for sure and patients have then to be controlled. As isoimmunisation could not be confirmed in any of our patients, postpartum Rh immune prophylaxis has to be administered even after detection of an antibody titer against 'D' after antepartum Rh prophylaxis. PMID:8514107

  19. 精品赏析

    Institute of Scientific and Technical Information of China (English)

    欧南

    2013-01-01

    费丽尔DECCA录音全集Kathleen Ferrier-The complete DECCA recordings演唱:凯瑟琳·费丽尔(Kathleen Ferrier)指挥:马尔科姆·萨金特(Malcolm Sargent)阿德里安·鲍尔特(Adrian Boult)乐队:伦敦交响乐团(London Symphony Orchestra)BBC交响乐团(BBC Symphony Orchestra)编号:478 3589(DECCA)

  20. Measuring consumers' information acquisition and decision behaviour with the computerbased information display matrix

    DEFF Research Database (Denmark)

    Aschemann-Witzel, Jessica; Hamm, U.

    2011-01-01

    The former judgement that the process-tracing method information-display-matrix (IDM) lacks external validity should be questioned in the light of technical advances and changing consumer behaviour. The new research environment offers possibilities for a close-to-realistic refinement and further...... development of the method: starting points are choice of location, increased relevance of choice, individual adjustment of task structure, simplified navigation and realistic layout. Used in multi-measurement-approaches, the IDM can provide detailed background information about consumer information behaviour...... prior to decisions reached in interviews or choice experiments. The contribution introduces to the method and its´ development, use and (dis-)advantages. Results of a survey illustrate the options for analysis and indicate that consumer behaviour in the IDM, compared to face-to-face-interviews, is less...

  1. Validation of Monte Carlo model of HPGe detector for field-station measurement of airborne radioactivity

    Science.gov (United States)

    Šolc, J.; Kovář, P.; Dryák, P.

    2016-03-01

    A Monte Carlo (MC) model of a mechanically-cooled High Purity Germanium detection system IDM-200-V™ manufactured by ORTEC® was created, optimized and validated within the scope of the Joint Research Project ENV57 ``Metrology for radiological early warning networks in Europe''. The validation was performed for a planar source homogeneously distributed on a filter placed on top of the detector end cap and for point sources positioned farther from the detector by comparing simulated full-energy peak (FEP) detection efficiencies with the ones measured with two or three different pieces of the IDM detector. True coincidence summing correction factors were applied to the measured FEP efficiencies. Relative differences of FEP efficiencies laid within 8% that is fully satisfactory for the intended use of the detectors as instruments for airborne radioactivity measurement in field-stations. The validated MC model of the IDM-200-V™ detector is now available for further MC calculations planned in the ENV57 project.

  2. Seeding supermassive black holes with a non-vortical dark-matter subcomponent

    CERN Document Server

    Sawicki, Ignacy; Valkenburg, Wessel

    2013-01-01

    A perfect irrotational fluid with the equation of state of dust, Irrotational Dark Matter (IDM), is incapable of virializing and instead forms a cosmoskeleton of filaments with supermassive black holes at the joints. This stark difference from the standard cold dark matter (CDM) scenario arises because IDM must exhibit potential flow at all times, preventing shell-crossing from occurring. This scenario is applicable to general non-oscillating scalar-field theories with a small sound speed. Our model of combined IDM and CDM components thereby provides a solution to the problem of forming the observed billion-solar-mass black holes at redshifts of six and higher. In particular, as a result of the reduced vortical flow, the growth of the black holes is expected to be more rapid at later times as compared to the standard scenario.

  3. Desarrollo de metodología analítica para la determinación de contaminantes basada en el cálculo por deconvolución de perfiles isotópicos

    OpenAIRE

    Fabregat Cabello, Neus

    2015-01-01

    El análisis por dilución isotópica y espectrometría de masas (IDMS) es reconocido como una de las técnicas más potentes para obtener resultados altamente fiables y de gran calidad metrológica en el campo de la química analítica. IDMS destaca como la forma de cuantificación más adecuada ante determinaciones realizadas en matrices de alta complejidad, siendo por ello ampliamente utilizado durante el acoplamiento de las técnicas de cromatografía a la espectrometría de masas. Además IDMS también ...

  4. Object Classification based Context Management for Identity Management in Internet of Things

    DEFF Research Database (Denmark)

    Mahalle, Parikshit N.; Prasad, Neeli R.; Prasad, Ramjee

    2013-01-01

    As computing technology is becoming more tightly coupled into dynamic and mobile world of the Internet of Things (IoT), security mechanism is more stringent, flexible and less intrusive. Scalability issue in IoT makes identity management (IdM) of ubiquitous objects more challenging, and there is ......As computing technology is becoming more tightly coupled into dynamic and mobile world of the Internet of Things (IoT), security mechanism is more stringent, flexible and less intrusive. Scalability issue in IoT makes identity management (IdM) of ubiquitous objects more challenging......, and there is a need of context-aware access control solution for IdM. Confronting uncertainty of different types of objects in IoT is not easy. This paper presents the logical framework for object classification in context aware IoT, as richer contextual information creates an impact on the access control. This paper...

  5. Determination of Trace Iron in Red Wine by Isotope Dilution Mass Spectrometry Using Multiple-Collector Inductively Coupled Plasma Mass Spectrometry

    International Nuclear Information System (INIS)

    This paper introduces determination of trace iron in red wine certified reference material by isotope dilution mass spectrometry (IDMS) method using a multiplecollector inductively coupled plasma mass spectrometry, equipped with a hexapole collision cell. The measurement procedure of iron isotopic abundance ratios was deeply researched. Reduced polyatomic ion interferences to iron isotopes ion by collision reaction using Ar and H2 gas, high precise isotopic abundance ratios were achieved. Two relative measurement methods (ICP-MS and ICP-OES) were used to analyze trace iron in red wine. The results are compared with IDMS results, which indicate that they are accordant. The uncertainty analyses include each uncertainty factor in whole experiment and the uncertainty of used certified reference material and it shows that the procedure blank is not neglectable to detect limit and precision of the method. The establishment of IDMS method for analysis of trace iron in red wine supports the certification of certified reference materials. (authors)

  6. An uncertainty budget for trace analysis by isotope-dilution ICP-MS with proper consideration of correlation

    International Nuclear Information System (INIS)

    Isotope-dilution mass spectrometry (IDMS) is considered to be a method without significant correction factors. It is also believed that this method is well understood. But unfortunately a large number of different uncertainty budgets have been published that consider different correction factors. These differences lead to conflicting combined uncertainties especially in trace analysis. It is described how the known correction factors must be considered in the uncertainty budget of values determined by IDMS combined with ICP-MS (ICP-IDMS). The corrections applied are dead time, background, interference, mass discrimination, blank correction and air buoyancy. IDMS measurements consist always of a series of isotope abundance ratio measurements and can be done according to different measurement protocols. Because the measurement protocols of IDMS are often rather sophisticated, correlations of influence quantities are difficult to identify. Therefore the measurement protocol has to be carefully considered in the specification of the measurand and a strategy is presented to properly account for these correlations. This will be exemplified for the estimation of mass fractions of platinum group elements (PGEs) and Re in the geological reference material UB-N (from CRPG-CNRS, Nancy in France) with ICP-IDMS. The PGEs with more than one isotope and the element Re are measured with on-line cation-exchange chromatography coupled to a quadrupole ICP-MS. All contents are below 10 μg kg-1. Only osmium is separated from the matrix by direct sparging of OsO4 into the plasma. This leads to transient signals for all PGEs and Re. It is possible to estimate the combined uncertainties and keep them favourably small despite the low contents, the transient signals and the sophisticated correction model. (orig.)

  7. An uncertainty budget for trace analysis by isotope-dilution ICP-MS with proper consideration of correlation

    Energy Technology Data Exchange (ETDEWEB)

    Moser, J.; Wegscheider, W.; Meisel, T.; Fellner, N. [Department of General and Analytical Chemistry, University of Leoben, 8700, Leoben (Austria)

    2003-09-01

    Isotope-dilution mass spectrometry (IDMS) is considered to be a method without significant correction factors. It is also believed that this method is well understood. But unfortunately a large number of different uncertainty budgets have been published that consider different correction factors. These differences lead to conflicting combined uncertainties especially in trace analysis. It is described how the known correction factors must be considered in the uncertainty budget of values determined by IDMS combined with ICP-MS (ICP-IDMS). The corrections applied are dead time, background, interference, mass discrimination, blank correction and air buoyancy. IDMS measurements consist always of a series of isotope abundance ratio measurements and can be done according to different measurement protocols. Because the measurement protocols of IDMS are often rather sophisticated, correlations of influence quantities are difficult to identify. Therefore the measurement protocol has to be carefully considered in the specification of the measurand and a strategy is presented to properly account for these correlations. This will be exemplified for the estimation of mass fractions of platinum group elements (PGEs) and Re in the geological reference material UB-N (from CRPG-CNRS, Nancy in France) with ICP-IDMS. The PGEs with more than one isotope and the element Re are measured with on-line cation-exchange chromatography coupled to a quadrupole ICP-MS. All contents are below 10 {mu}g kg{sup -1}. Only osmium is separated from the matrix by direct sparging of OsO{sub 4} into the plasma. This leads to transient signals for all PGEs and Re. It is possible to estimate the combined uncertainties and keep them favourably small despite the low contents, the transient signals and the sophisticated correction model. (orig.)

  8. Cord Serum Lipid Profile of Infants of Diabetic Mothers

    Directory of Open Access Journals (Sweden)

    Jasim Almusawi

    2015-12-01

    Full Text Available Background: Infants of diabetic mothers (IDM is a critical issue in pediatrics, which is regarded as a major risk factor for birth trauma, respiratory distress syndrome (RDS, birth asphyxia, transient tachypnea of the newborn (TTN and jaundice. IDM is also a risk factor for microvascular (e.g., ocular and renal complications and macrovascular complications (e.g., cerebrovascular accident, atherosclerosis and cardiovascular complications. Lipids are a heterogeneous group of hydrophobic organic molecules which can be extracted from tissues using non-polar solvents. Lipids, due to their hydrophobic property, are mainly found in membranes enclosing various cell organelles. Diabetes mellitus management with insulin (nowadays also with oral hypoglycemic medications has improved the outcomes of gestational diabetes mellitus (GDM (most infants born to diabetic mother are large for gestational age. The neonatal mortality rate in IDM is over five times higher than that of infants of non-diabetic mothers. In this study, therefore, we aimed to assess the effect of maternal diabetes on cord serum lipid profile. Methods: This prospective (case-control study was carried out on 60 infants born in Al-Zahra teaching hospital during February 2014–October 2014. The study group consisted of 30 randomly chosen IDM, and the control group comprised 30 infants who were born to healthy mothers. Results: The results of this study demonstrated that there are significant differences between IDM and infants of healthy mothers regarding lipid profile and birth weight. Conclusion: This study confirms that cord serum lipid profile (serum cholesterol, serum triglycerides and low-density lipoprotein is higher at birth in IDM. Moreover, this study shows a significant association between lipid profile and body weight.

  9. Digital Solutions for Informed Decision Making: An Academic-Community Partnership for the Development of a Prostate Cancer Decision Aid for African American Men.

    Science.gov (United States)

    Owens, Otis L; Friedman, Daniela B; Brandt, Heather M; Bernhardt, Jay M; Hébert, James R

    2016-05-01

    African American (AA) men are significantly more likely to die of prostate cancer (PrCA) than other racial groups, and there is a critical need to identify strategies for providing information about PrCA screening and the importance of informed decision making (IDM). To assess whether a computer-based IDM intervention for PrCA screening would be appropriate for AA men, this formative evaluation study examined their (1) PrCA risk and screening knowledge; (2) decision-making processes for PrCA screening; (3) usage of, attitudes toward, and access to interactive communication technologies (ICTs); and (4) perceptions regarding a future, novel, computer-based PrCA education intervention. A purposive convenience sample of 39 AA men aged 37 to 66 years in the Southeastern United States was recruited through faith-based organizations to participate in one of six 90-minute focus groups and complete a 45-item descriptive survey. Participants were generally knowledgeable about PrCA. However, few engaged in IDM with their doctor and few were informed about the associated risks and uncertainties of PrCA screening. Most participants used ICTs on a daily basis for various purposes including health information seeking. Most participants were open to a novel, computer-based intervention if the system was easy to use and its animated avatars were culturally appropriate. Because study participants had low exposure to IDM for PrCA, but frequently used ICTs, IDM interventions using ICTs (e.g., computers) hold promise for AA men and should be explored for feasibility and effectiveness. These interventions should aim to increase PrCA screening knowledge and stress the importance of participating in IDM with doctors. PMID:25563381

  10. Identity as a Service - Towards a Service-Oriented Identity Management Architecture

    OpenAIRE

    Emig, Christian; Brandt, Frank; Kreuzer, Sebastian; Abeck, Sebastian

    2007-01-01

    Service-oriented architecture (SOA) will form the basis of future information systems. Web services are a promising way to implement SOA enabling the loose coupling of functionality at service interfaces. The focus in SOA changes from traditional software systems to reusable, business-relevant services. Considering the cross-cutting concern of identity management (IdM), it is still an open issue how to construct an SOA-aware IdM architecture enabling “identity as a service” and how to loosely...

  11. An Access Control Metamodel for Web Service-Oriented Architecture

    OpenAIRE

    Emig, Christian; Brandt, Frank; Abeck, Sebastian; Biermann, Jürgen; Klarl, Heiko

    2008-01-01

    With the mutual consent to use WSDL (Web Service Description Language) to describe web service interfaces and SOAP as the basic communication protocol, the cornerstone for web service-oriented architecture (WSOA) has been established. Considering the momentum observable by the growing number of specifications in the web service domain for the indispensable cross-cutting concern of identity management (IdM) it is still an open issue how a WSOA-aware IdM architecture is built and how it is link...

  12. Determination of the rare earth elements in marine pore waters and associated sediments

    International Nuclear Information System (INIS)

    Accurate and precise determinations of natural levels of rare earth elements (R.E.E.) in sea water and pore water are highly reliant upon the size and variability of the analytical blank, the method for determining the yield, and, to a lesser extent, the inherent precision of the instrument used. Isotope dilution mass spectrometry (IDMS) together with ultra-clean room techniques has been successfully used in the determinations of rare earth elements in pore waters. Simultaneous multi-element analysis by inductively coupled plasma atomic emission spectrometry (ICP) provides an alternative to IDMS for a rapid determination of R.E.E. in sediments. (author)

  13. Identifizierung von essentiellen Genen in Salmonella typhimurium und Listeria monocytogenes durch Genom-weite Insertions-Duplikations-Mutagenese

    OpenAIRE

    Knuth, Karin

    2004-01-01

    Die in dieser Arbeit etablierte Insertions-Duplikations-Mutagenese IDM ermöglicht es, das Genom von pathogenen Bakterien zu mutagenisieren und die so generierte Mutantenbank im high-throughput-Format auf Gene zu untersuchen, die unter bestimmten Bedingungen für das infektiöse Potential oder für das Überleben dieser Keime von Bedeutung sind. Die Grundlage von IDM bildet ein konditional replizierender Vektor, in den eine Genbank des Wirtsorganismus kloniert wird und der unter nicht-permissiven ...

  14. A systematic halo-independent analysis of direct detection data within the framework of Inelastic Dark Matter

    International Nuclear Information System (INIS)

    We present a systematic halo-independent analysis of available Weakly Interacting Massive Particles (WIMP) direct detection data within the framework of Inelastic Dark Matter (IDM). We show that, when the smallest number of assumptions is made on the WIMP velocity distribution in the halo of our Galaxy, it is possible to find values of the WIMP mass and the IDM mass splitting for which compatibility between present constraints and any of the three experiments claiming to see a WIMP excess among DAMA, CDMS-Si and CRESST can be achieved

  15. Impact of Two Realistic Mobility Models for Vehicular Safety Applications

    OpenAIRE

    RAHMAN, Md. Habibur; Nasiruddin, Mohammad

    2014-01-01

    Vehicular safety applications intended for VANETs. It can be separated by inter-vehicle communication. It is needed for a vehicle can travel safety with high velocity and must interconnect quickly dependably. In this work, examined the impact of the IDM-IM and IDM-LC mobility model on AODV, AOMDV, DSDV and OLSR routing protocol using Nakagami propagation model and IEEE 802.11p MAC protocol in a particular urban scenario of Dhaka city. The periodic broadcast (PBC) agent is employed to transmit...

  16. Integrated Distribution Management System for Alabama Principal Investigator

    Energy Technology Data Exchange (ETDEWEB)

    Schatz, Joe

    2013-03-31

    Southern Company Services, under contract with the Department of Energy, along with Alabama Power, Alstom Grid (formerly AREVA T&D) and others moved the work product developed in the first phase of the Integrated Distribution Management System (IDMS) from “Proof of Concept” to true deployment through the activity described in this Final Report. This Project – Integrated Distribution Management Systems in Alabama – advanced earlier developed proof of concept activities into actual implementation and furthermore completed additional requirements to fully realize the benefits of an IDMS. These tasks include development and implementation of a Distribution System based Model that enables data access and enterprise application integration.

  17. Object Classification based Context Management for Identity Management in Internet of Things

    OpenAIRE

    Mahalle, Parikshit N.; Prasad, Neeli R.; Prasad, Ramjee

    2013-01-01

    As computing technology is becoming more tightly coupled into dynamic and mobile world of the Internet of Things (IoT), security mechanism is more stringent, flexible and less intrusive. Scalability issue in IoT makes identity management (IdM) of ubiquitous objects more challenging, and there is a need of context-aware access control solution for IdM. Confronting uncertainty of different types of objects in IoT is not easy. This paper presents the logical framework for object classification i...

  18. Kõlab õuduste sümfoonia / Kaupo Meiel

    Index Scriptorium Estoniae

    Meiel, Kaupo, 1975-

    2004-01-01

    PÖFFi Suvekino raames jõuab 11. juunil Pärnusse nn "Nosferatu tuur" ehk saksa tummfilmiklassika - Friedrich Wilhelm Murnau filmi "Nosferatu - õuduste sümfoonia" ("Nosferatu - Eine Symphonie des Grauens", 1921) ringreis koos ansambliga Kriminaalne Elevant (Kaspar Jancis, Danel Aljo, Eno Kollom, Hannes Kivi, Henry Tiisma)

  19. Nosferatu Pärnus

    Index Scriptorium Estoniae

    2004-01-01

    PÖFFi Suvekino raames algab mööda Eestit nn "Nosferatu tuur" ehk saksa tummfilmiklassika - Friedrich Wilhelm Murnau filmi "Nosferatu - õuduste sümfoonia" ("Nosferatu - Eine Symphonie des Grauens", 1921) ringreis koos ansambliga Kriminaalne Elevant (Kaspar Jancis, Danel Aljo, Eno Kollom, Hannes Kivi, Henry Tiisma)

  20. PÖFF-i suvekino : Nosferatu hirmufilmi show Katariina kirikus

    Index Scriptorium Estoniae

    2004-01-01

    PÖFFi Suvekino raames algab mööda Eestit nn "Nosferatu tuur" ehk saksa tummfilmiklassika - Friedrich Wilhelm Murnau filmi "Nosferatu - õuduste sümfoonia" ("Nosferatu - Eine Symphonie des Grauens", 1921) ringreis koos ansambliga Kriminaalne Elevant (Kaspar Jancis, Danel Aljo, Eno Kollom, Hannes Kivi, Henry Tiisma)

  1. General Agreement on Tariff and Trade Negotiations: A Computer-Based Simulation.

    Science.gov (United States)

    Manrique, Gabriel G.

    This paper recommends the use of a computer simulation about trade and tariff negotiations to reinforce and apply principles learned in undergraduate international trade courses and to provide students with an opportunity to use the advanced features of Symphony, a computer spreadsheet. This simulation is a game in which both the class and…

  2. Pilk maestro Neeme Järvi muusikalisse loometöösse / Airi Vaga

    Index Scriptorium Estoniae

    Vaga, Airi, 1940-

    2006-01-01

    kohtumisest New Jersey Symphony Orchestra mängijate ja dirigendiga 13. jaanuaril 2006 Newarkis, kus tutvustati sümfooniaorkestri 2006 - 2007. aasta programmi ning räägiti tööst Beethoveni 9. sümfoonia ettevalmistamisel kontserdiks. Tunti muret noorte muusikakasvatuse ühekülgse arengu pärast

  3. Nederlandse muziek bij Nederlandse symfonieorkesten 1945-2000

    NARCIS (Netherlands)

    Overbeeke, E.

    2012-01-01

    Symphony orchestras play a crucial role in Dutch musical life. They not only give composers the opportunity to present their music and give musicians and listeners the chance to get acquainted with new music, they also have own ideas about presenting which music in which setting. This dissertation d

  4. Things to Remember about El Sistema: A Response to "El Sistema--A Perspective for North American Music Educators" by Tricia Tunstall

    Science.gov (United States)

    Lesniak, Melissa

    2013-01-01

    Melissa Lesniak, the executive director of the Greater Miami Youth Symphony, discusses how much she enjoyed reading the responses to her "El Sistema" article and appreciates the opportunity for healthy dialogue and debate. In response, she states that there are many common goals and objectives across all music education programs that can…

  5. The Story of Carora: The Origins of El Sistema

    Science.gov (United States)

    Carlson, Alexandra

    2016-01-01

    Venezuela's youth symphony program, the Fundación Musical Simón Bolívar, commonly referred to as "El Sistema," combines musical achievement with learning important life skills through orchestral practice and performance. Although the history most commonly reported outside Venezuela is of the program's director, José Antonio Abreu,…

  6. Using Web Services for a Mobile OPAC

    Directory of Open Access Journals (Sweden)

    Denis Galvin

    2011-04-01

    Full Text Available The purpose of this paper is to discuss the creation and intended evolution of the Rice University mobile online public access catalog (OPAC. The focus of the article is on how SirsiDynix’s Symphony Web Services can be used to create a mobile OPAC.

  7. How Universal Is Beethoven?: Music, Culture, and Democracy

    Science.gov (United States)

    Whale, Mark

    2015-01-01

    Daniel Barenboim, conductor of the Arab/Israeli West-Eastern Divan Orchestra, claims that "everywhere in the world … [Beethoven's Ninth Symphony] speaks to all people." But just how universal is Beethoven? Does his music exceed cultural boundaries or is Barenboim's idea of a "utopian republic," built, in part, upon Beethoven's…

  8. World beyond Pluto

    CERN Document Server

    Marlowe, Stephen

    2014-01-01

    What happens when a hardened criminal on the run for his life gets mixed up with an all-girl symphony traveling between lesser-populated planets in a futile attempt to bring culture to their rowdy inhabitants? Well, to put it mildly, hijinks ensue. Read Stephen Marlowe's thoroughly entertaining World Beyond Pluto to find out the rest.

  9. Towards a Transcultural Theory of Democracy for Instrumental Music Education

    Science.gov (United States)

    Tan, Leonard

    2014-01-01

    At present, instrumental music education, defined in this paper as the teaching and learning of music through wind bands and symphony orchestras of Western origin, appears embattled. Among the many criticisms made against instrumental music education, critics claim that bands and orchestras exemplify an authoritarian model of teaching that does…

  10. Once More unto the Breach: Aesthetic Experience Revisited

    Science.gov (United States)

    Hansen, Forest

    2015-01-01

    Aesthetic experience as a determining factor in music appreciation has lost salience in recent years, especially in philosophy of music education. Markand Thakar, music director of the Baltimore Chamber Orchestra and Duluth Superior Symphony Orchestra and co-director of graduate conducting at Peabody Conservatory, has written a book subtitled…

  11. Pop / Priit Hõbemägi

    Index Scriptorium Estoniae

    Hõbemägi, Priit, 1957-

    2006-01-01

    Heliplaatidest: The Manhattan Transfer "The Symphony Sessions", The Magic Numbers "Those The Brokes", Electronic "Get the Message: the Best of Electronic", ...And You Will Know Us by the Trail of Dead "So Divided", Tutty Moreno "Magica", Lindsey Buckingham "Under the Skin"

  12. Ujuv saadik / Triin Ojari

    Index Scriptorium Estoniae

    Ojari, Triin, 1974-

    2010-01-01

    Kohtumisest Eestis viibinud Louis Kahni projekteeritud kontserdilaeval ringi sõitva American Wind Symphony Orchresta juhataja Robert Boudreau'ga. Laeva sünnist, tema loojast, laeva tulevikust, Eestis 2011. a. kontserttuuri tegemisest. Eesti Arhitektide Liidu ideest osta 2011. a. kultuuripealinna ürituste raames toimuva L. Kahnile pühendatud seminari puhuks tema kavandatud kontserdilaev

  13. Muusikamaailm : Tšehhi Filharmoonikud Ashkenazyga. Swansea festivali lõpetas Paavo Järvi. Steieri sügisfestivalilt. Ooperifestival Wexfordis / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    1999-01-01

    Tšehhi. Filh. Ork. kontserdireisist Inglismaale uue peadirigendi V.Ashkenazy juhatusel. Swansea sügisfestivalist Walesimaal. 23. okt. toimunud rahvusvahelisest Euroopa Ringhäälingute Liidu ooperiõhtu ülekandest Euroraadios. Uue muusika festivalist "Steirische Herbst" Austrias. Wexfordi ooperifestivalist Iirimaal/Tšehhi Filharmoonia Orkester//BBC Walesi Rahvusorkester//City of Birmingham Symphony Orchestra

  14. Valued Estonian Music CDs

    Index Scriptorium Estoniae

    2004-01-01

    2002. aastal välja antud eesti muusika heliplaatidest Artur Kapp "Symphonische Werke", Eduard Tubin "Symphonies No.9, No.10 and No.11", "Estonian Preludes", "Eesti heliloojad. Hortus Musicus", "Eesti Muusika Päevad", "Tallinn Saxophone Quartet. Estonian Contemporary Music", "Triskele. Kolga-Jaani vaimulikud rahvalaulud", "Helmekaala. Linnupuu Anne", "Modern Fox mängib Raimond Valgret",

  15. Knowledge work and communication challenges in networked enterprises

    NARCIS (Netherlands)

    Barjis, J.; Gupta, A.; Sharda, R.

    2010-01-01

    A modern enterprise is a heavily wired and networked socio-technical system where multiple components play in symphony to yield a competitive position in the ear of digital economy. While the underling communication and interaction systems facilitate knowledge workers to carry out the enterprise mis

  16. Concerts & Opera

    Index Scriptorium Estoniae

    2008-01-01

    Kristjan Järvi dirigeerimas Vienna Tonkünstler Orchestra't 16. veebr. Leedsis Town Hallis (esitusel ka Arvo Pärdi Symphony No. 3), 20. veebr. Bristolis ja 23. veebr. Basingstoke'is. Neeme Järvi dirigeerimas Royal Scottish National Orcestra't 23. veebr. Glasgowis Royal Concert Hallis ja 24. veebr. Edinburghis Queens Hallis

  17. The Art Institution in a Globalizing World

    NARCIS (Netherlands)

    Gielen, Pascal

    2010-01-01

    How do oclassicalo big art institutions (museums, the ballet, the opera, symphony orchestras) react to phenomena of globalization such as migration flows, the odenationalizationo of artistic movements, the enormous growth of the number of artists, the trend of a global cultural branding of cities, e

  18. Muusikamaailm : Wien Modern 2001. "Taanit avastamas". Malcolm Arnold 80. Halina Czerny-Stefanska lahkunud / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2001-01-01

    28.Xئ26.XI Wienis toimuvast nüüdismuusikafestivalist "Wien Modern". Birminghami Symphony Hallis korraldati kolmenädalane kontserdisari "Discover Denmark". Inglise helilooja, trompetisti ja dirigendi Malcolm Arnoldi 80. sünniaastapäevale pühendatud üritustest. Suri nimekas poola pianist Halina Czerny-Stefanska

  19. Tank 241-AY-102 Leak Assessment Supporting Documentation: Miscellaneous Reports, Letters, Memoranda, And Data

    International Nuclear Information System (INIS)

    This report contains reference materials cited in RPP-ASMT -53793, Tank 241-AY-102 Leak Assessment Report, that were obtained from the National Archives Federal Records Repository in Seattle, Washington, or from other sources including the Hanford Site's Integrated Data Management System database (IDMS)

  20. Syndrome coronarien aigu en post-partum secondaire à une dissection coronaire spontanée: à propos d'un cas

    Science.gov (United States)

    El Malki Berrada, Nabil; Zaimi, Achraf; Ezzouak, Abdellatif; Belhachmi, Hassan; Lagziri, Alaeeddine; Ratbi, Sara; eddine Elyounassi, Badre

    2015-01-01

    L'IDM per gravidique est une complication grave qui entraine une morbidité et une mortalité maternelle élevée. Bien que l'athérosclérose soit la cause d'IDM la plus fréquente dans la population générale, elle n'est observée que chez un tiers des femmes enceintes. Chez ces dernières, la cause la plus fréquente d'IDM était la dissection coronaire. Nous rapportons l'observation clinique d'une jeune femme de 24 ans, sans facteur de risque cardiovasculaire, qui a présenté un IDM antérieur étendu 15 jours après un accouchement, en rapport avec une dissection de la partie proximale de l'artère inter ventriculaire antérieure. Le traitement de cette pathologie n'est pas consensuel, et peut faire appel, selon la présentation clinique et angiographique, au traitement médical, à une revascularisation par pontage aorto-coronaire avec une résection de l'hématome de la paroi artérielle, ou à l'angioplastie transluminale. Le pronostic semble assez favorable quoique controversé. PMID:26161172

  1. Information delivery manuals to integrate building product information into design

    DEFF Research Database (Denmark)

    Berard, Ole Bengt; Karlshøj, Jan

    2011-01-01

    . Traditional business process modeling languages often fail to completely cover all four perspectives. BuildingSMART has proposed Information Delivery Manuals (IDMs) to model and re-engineer processes that address the four perspectives through a collaborative methodology in order to standardize and implement...

  2. Information delivery manuals to integrate building product information into design

    DEFF Research Database (Denmark)

    Berard, Ole Bengt; Karlshøj, Jan

    2013-01-01

    . Traditional business process modeling languages often fail to completely cover all four perspectives. BuildingSMART has proposed Information Delivery Manuals (IDMs) to model and re-engineer processes that address the four perspectives through a collaborative methodology in order to standardize and implement...

  3. RECODE: Design and baseline results of a cluster randomized trial on cost-effectiveness of integrated COPD management in primary care

    NARCIS (Netherlands)

    A.L. Kruis (Annemarije); M.R.S. Boland (Melinde); C.H. Schoonvelde (Catharina H.); W.J.J. Assendelft (Willem); M.P.M.H. Rutten-van Mölken (Maureen); J. Gussekloo (Jacobijn); A. Tsiachristas (Apostolos); N.H. Chavannes (Nicolas)

    2013-01-01

    markdownabstract__Abstract__ Background: Favorable effects of formal pulmonary rehabilitation in selected moderate to severe COPD patients are well established. Few data are available on the effects and costs of integrated disease management (IDM) programs on quality of care and health status of CO

  4. Modeling Method for Increased Precision and Scope of Directly Measurable Fluxes at a Genome-Scale

    DEFF Research Database (Denmark)

    McCloskey, Douglas; Young, Jamey D.; Xu, Sibei;

    2016-01-01

    pathways of traditional MFA models and also covers the additional pathways of purine, pyrimidine, isoprenoid, methionine, riboflavin, coenzyme A, and folate, as well as other biosynthetic pathways. When evaluating the iDM2014 using a set of measured intracellular intermediate and cofactor mass isotopomer...

  5. Analysis of Sub-picogram Plutonium by Isotope Mass Spectrometry%亚皮克量级钚的质谱分析技术

    Institute of Scientific and Technical Information of China (English)

    龙开明; 汤磊; 贾宝亭; 刘雪梅; 杨天丽; 刘钊

    2005-01-01

    By using active carbon powder as ionization enhance matter, the detect sensitivity of 239Pu ,which was 0.5 pg (1±0.15, 95% confidence level), was about 20 times that of the tradition method. The sub-picogram plutonium sample was determined quantitatively by isotope dilution mass spectrometry (IDMS).

  6. Keeping identity private

    DEFF Research Database (Denmark)

    Adjei, Joseph K.; Olesen, Henning

    2011-01-01

    attempt to understand the relationship between individuals’ intentions to disclose personal information, their actual personal information disclosure behaviours, and how these can be leveraged to develop privacy-enhancing identity management systems (IDMS) that users can trust. Legal, regu-latory and...

  7. Exploring an informed decision-making framework using in-home sensors: older adults’ perceptions

    Directory of Open Access Journals (Sweden)

    Jane Chung

    2014-03-01

    Full Text Available Background Sensor technologies are designed to assist independent living of older adults. However, it is often difficult for older adults to make an informed decision about adopting sensor technologies.Objective To explore Bruce’s framework of informed decision making (IDM for in-home use of sensor technologies in community-dwelling elders.Method The IDM framework guided development of a semi-structured interview. A theory-driven coding approach was used for analysis.Results Participants supported most of the elements of the framework, but not all aspects of each element were addressed. Perceived usefulness of technologies was identified as an area for framework extension.Conclusion This paper provides useful information for health care professionals to consider how to enhance IDM of older adults regarding the use of sensor technologies. The results also illuminate elements of the IDM framework that may be critical to facilitating independent living for older adults.

  8. 75 FR 22114 - Aluminum Extrusions from the People's Republic of China: Initiation of Countervailing Duty...

    Science.gov (United States)

    2010-04-27

    ... Rule, 62 FR 27296, 27323 (May 19, 1997)), we are setting aside a period for interested parties to raise..., 74 FR 37012 (July 27, 2009)(``KASR from the PRC''), and accompanying IDM at Comment 3. C. Tax... International Trade Administration (C-570-968) Aluminum Extrusions from the People's Republic of...

  9. The role of the IHS library in supporting a distance learning programme: a practical assignment based on the experience of the Institute for Housing and Urban Development Studies (IHS)

    NARCIS (Netherlands)

    N.J.W. Browne

    2001-01-01

    textabstractThis report is the final activity for the Integral Document Management (IDM) post-graduate course, and describes a practical assignment on what happened during a pilot project on distance learning at the Institute for Housing and Urban Development Studies (IHS). The focus is on the futur

  10. 76 FR 33194 - Pure Magnesium From the People's Republic of China: Preliminary Results of the 2009-2010...

    Science.gov (United States)

    2011-06-08

    ... Fair Value: Antidumping Duty Investigation of Pure Magnesium From the Russian Federation, 60 FR 25691... Antidumping Duty Administrative Review, 73 FR 76336 (December 16, 2008)(``Pure Magnesium 06-07''); and... FR 76336 (December 16, 2008) and accompanying IDM (``2006-2007 Pure Magnesium Review'')...

  11. 78 FR 34646 - Pure Magnesium from the People's Republic of China: Preliminary Results of 2011-2012 Antidumping...

    Science.gov (United States)

    2013-06-10

    ... Economy Antidumping Proceedings: Assessment of Antidumping Duties, 76 FR 65694, 65694-95 (October 24, 2011... and New Shipper Reviews, and Final Rescission of New Shipper Review, 65 FR 20948 (April 19, 2000), and... Fourth Antidumping Duty Administrative Review, 69 FR 54635 (September 9, 2004), and accompanying IDM...

  12. Production of highly-enriched 134Ba for a reference material for isotope dilution mass spectrometry measurements

    International Nuclear Information System (INIS)

    Isotope dilution mass spectrometry (IDMS) is an analytical technique capable of providing accurate and precise quantitation of trace isotope abundance and assay providing measurement uncertainties below 1 %. To achieve these low uncertainties, the IDMS method ideally utilizes chemically pure 'spike' solutions that consist of a single highly enriched isotope that is well-characterized relating to the abundance of companion isotopes and concentration in solution. To address a current demand for accurate 137Cs/137Ba ratio measurements for 'age' determination of radioactive 137Cs sources, Idaho National Laboratory (INL) is producing enriched 134Ba isotopes that are tobe used for IDMS spikes to accurately determine 137Ba accumulation from the decay of 137Cs. The final objective of this work it to provide a homogenous set of reference materials that the National Institute of Standards and Technology can certify as standard reference materials used for IDMS. The process that was developed at INL for the separation and isolation of Ba isotopes, chemical purification of the isotopes in solution, and the encapsulation of the materials will be described. (author)

  13. Interface Finite Elements for the Analysis of Fracture Initiation and Progression

    Science.gov (United States)

    Ambur, Damodar R. (Technical Monitor); Johnson, Eric R.

    2003-01-01

    Progressive failure analyses (PFA) are important for the prediction of residual strength and damage tolerance of vehicle structures, and to predict the energy absorbing capability of vehicle structures under crash-type loads. Typically continuum damage mechanics (CDM) and fracture mechanics (FM) are the methods used for PFA. The method of interfacial damage mechanics (IDM) is used for PFA in this research. IDM has capabilities intermediate between CDM and FM, and is used to numerically model the initiation, growth, and arrest of cracks. IDM smooths the stress singularity at the crack tip, and is easily adaptable with other nonlinearties such as plasticity and material damage. IDM is implemented by user-defined interface elements in the ABAQUS/ Standard structural analysis software package. The structural components selected to demonstrate the effectiveness PFA using interface elements are, for the most part, those with published test data. These structural components were subjected to quasi-static loading in the tests. Thus, the ABAQUS analyses are used to predict geometrically and materially nonlinear equilibrium states. Impact loading, dynamic fracture, reflected stress waves, inertia, and time dependent material behavior are not considered.

  14. Ready the Pipes

    Science.gov (United States)

    Grayson, Katherine

    2010-01-01

    If there's anyone in the academic IT arena taking seriously the possibility that campus identity management (IdM) may one day meld with consumer apps, it's Nate Klingenstein, one of the founding members of the Shibboleth Project (the open source project providing architecture and policy structures for managing single sign-on access to resources).…

  15. A Study of Multimodal Discourse in the Design of Interactive Digital Material for Language Learning

    Science.gov (United States)

    Burset, Silvia; Bosch, Emma; Pujolà, Joan-Tomàs

    2016-01-01

    This study analyses some published interactive materials for the learning of Spanish as a f?irst language and English as a Foreign Language (EFL) commonly used in primary and secondary education in Spain. The present investigation looks into the relationships between text and image on the interface of Interactive Digital Material (IDM) to develop…

  16. Tank 241-AY-102 Leak Assessment Supporting Documentation: Miscellaneous Reports, Letters, Memoranda, And Data

    Energy Technology Data Exchange (ETDEWEB)

    Engeman, J. K.; Girardot, C. L.; Harlow, D. G.; Rosenkrance, C. L.

    2012-12-20

    This report contains reference materials cited in RPP-ASMT -53793, Tank 241-AY-102 Leak Assessment Report, that were obtained from the National Archives Federal Records Repository in Seattle, Washington, or from other sources including the Hanford Site's Integrated Data Management System database (IDMS).

  17. ITER ITA newsletter. No. 20, February-March 2005

    International Nuclear Information System (INIS)

    This issue of ITER ITA (ITER transitional Arrangements) newsletter contains concise information about ITER related activities including interview on the occasion of Academician E.P. Velikhov' 70th birthday conducted by Dr. Lev Golubbchikov, former ITER Contact Person of the Russian Federation and a new document management system of ITER called IDM (ITER Document Management), which supersedes the old IDoMS

  18. Decreased prostacyclin production in the infant of the diabetic mother

    Energy Technology Data Exchange (ETDEWEB)

    Stuart, M.J.; Sunderji, S.G.; Allen, J.B.

    1981-09-01

    Maternal diabetes mellitus is recognized to be a predisposing factor to thrombosis in the neonate. In the adult with diabetes, abnormalities in the metabolism of AA by the platelet and vessel wall occur, which result in an increase in proaggregatory platelet thromboxane A2. A decrease in antiaggregatory vascular PGI2 has been demonstrated in the diabetic rat, although conclusive proof of a similar abnormality is lacking in humans. We evaluated vascular AA metabolism in 10 IDM (groups II and III comparison to 20 control neonates of gestational ages 32 to 40 weeks (group I). Mean uptakes of labeled AA into vascular tissue of both controls and IDM were similar. The conversion of (14C) AA to 6-keto-PGF1 alpha was not dependent on gestational age (r . 0.223) in the control neonates, with a mean value of 5.2% +- 1.3 (1 S.D.). A marked decrease (p less than 0.001) in 6-keto-PGF1 alpha formation to 1.7% +- 0.3 was found in the group II IDM of mothers with poor diabetic control (HbA1c . 9.3% +- 0.5). In the group III neonates whose mothers had normal HBA1c levels (6.1% +- 0.9), 6-keto-PGF1 alpha production was normal at 4.9% +- 0.8. Although no correlation between maternal fasting blood glucose and neonatal 6-keto-PGF1 alpha was demonstrable, a significant inverse correlation (r . 0.872; p less than 0.02) was observed between maternal HbA1c levels and the conversion of AA to 6-keto-PGF1 alpha in the vascular tissues of the IDM. It appear possible that abnormalities in platelet-vascular AA metabolism may play an etiologic role in the vascular complications present in some IDM.

  19. Modeling the economic impact of medication adherence in type 2 diabetes: a theoretical approach

    Directory of Open Access Journals (Sweden)

    David S Cobden

    2010-08-01

    Full Text Available David S Cobden1, Louis W Niessen2, Frans FH Rutten1, W Ken Redekop11Department of Health Policy and Management, Section of Health Economics – Medical Technology Assessment (HE-MTA, Erasmus MC, Erasmus University Rotterdam, The Netherlands; 2Department of International Health, Johns Hopkins University School of Public Health, Johns Hopkins Medical Institutions, Baltimore, MD, USAAims: While strong correlations exist between medication adherence and health economic outcomes in type 2 diabetes, current economic analyses do not adequately consider them. We propose a new approach to incorporate adherence in cost-effectiveness analysis.Methods: We describe a theoretical approach to incorporating the effect of adherence when estimating the long-term costs and effectiveness of an antidiabetic medication. This approach was applied in a Markov model which includes common diabetic health states. We compared two treatments using hypothetical patient cohorts: injectable insulin (IDM and oral (OAD medications. Two analyses were performed, one which ignored adherence (analysis 1 and one which incorporated it (analysis 2. Results from the two analyses were then compared to explore the extent to which adherence may impact incremental cost-effectiveness ratios.Results: In both analyses, IDM was more costly and more effective than OAD. When adherence was ignored, IDM generated an incremental cost-effectiveness of $12,097 per quality-adjusted life-year (QALY gained versus OAD. Incorporation of adherence resulted in a slightly higher ratio ($16,241/QALY. This increase was primarily due to better adherence with OAD than with IDM, and the higher direct medical costs for IDM.Conclusions: Incorporating medication adherence into economic analyses can meaningfully influence the estimated cost-effectiveness of type 2 diabetes treatments, and should therefore be ­considered in health care decision-making. Future work on the impact of adherence on health

  20. Decreased prostacyclin production in the infant of the diabetic mother

    International Nuclear Information System (INIS)

    Maternal diabetes mellitus is recognized to be a predisposing factor to thrombosis in the neonate. In the adult with diabetes, abnormalities in the metabolism of AA by the platelet and vessel wall occur, which result in an increase in proaggregatory platelet thromboxane A2. A decrease in antiaggregatory vascular PGI2 has been demonstrated in the diabetic rat, although conclusive proof of a similar abnormality is lacking in humans. We evaluated vascular AA metabolism in 10 IDM (groups II and III comparison to 20 control neonates of gestational ages 32 to 40 weeks (group I). Mean uptakes of labeled AA into vascular tissue of both controls and IDM were similar. The conversion of [14C] AA to 6-keto-PGF1 alpha was not dependent on gestational age (r . 0.223) in the control neonates, with a mean value of 5.2% +- 1.3 (1 S.D.). A marked decrease (p less than 0.001) in 6-keto-PGF1 alpha formation to 1.7% +- 0.3 was found in the group II IDM of mothers with poor diabetic control (HbA1c . 9.3% +- 0.5). In the group III neonates whose mothers had normal HBA1c levels (6.1% +- 0.9), 6-keto-PGF1 alpha production was normal at 4.9% +- 0.8. Although no correlation between maternal fasting blood glucose and neonatal 6-keto-PGF1 alpha was demonstrable, a significant inverse correlation (r . 0.872; p less than 0.02) was observed between maternal HbA1c levels and the conversion of AA to 6-keto-PGF1 alpha in the vascular tissues of the IDM. It appear possible that abnormalities in platelet-vascular AA metabolism may play an etiologic role in the vascular complications present in some IDM

  1. Towards Verification of Constituent Systems through Automated Proof

    DEFF Research Database (Denmark)

    Couto, Luis Diogo Monteiro Duarte; Foster, Simon; Payne, R

    2014-01-01

    This paper explores verification of constituent systems within the context of the Symphony tool platform for Systems of Systems (SoS). Our SoS modelling language, CML, supports various contractual specification elements, such as state invariants and operation preconditions, which can be used to...... specify contractual obligations on the constituent systems of a SoS. To support verification of these obligations we have developed a proof obligation generator and theorem prover plugin for Symphony. The latter uses the Isabelle/HOL theorem prover to automatically discharge the proof obligations arising...... from a CML model. Our hope is that the resulting proofs can then be used to formally verify the conformance of each constituent system, which is turn would result in a dependable SoS....

  2. Continuous pulse oximetry in the general surgical ward: Nellcor N-200 versus Nellcor N-3000

    DEFF Research Database (Denmark)

    Christensen, M; Lie, C; Rosenberg, J

    1999-01-01

    New measurement principles in pulse oximetry have been introduced to decrease the incidence of false movement alarms. Experimental studies have shown that the new Nellcor Symphony N-3000 may reduce the incidence of false alarms when monitoring during different activities. We compared the Nellcor...... Symphony N-3000 with the Nellcor N-200 pulse oximeter, when monitoring patients in the general surgical ward. Twenty-two patients were monitored during unrestricted ward activities for a total of 275 h with a N-3000 and a N-200 pulse oximeter simultaneously. Data were analysed for lack of concordance...... between the two pulse oximeters with respect to frequency of registered hypoxaemic episodes and thus the amount of time spent in the alarm state. The median number of desaturation episodes with the N-200 was 18 (range 0-511) compared with four (range 0-476) with the N-3000 (p < 0.0001). The median number...

  3. An acoustical investigation of the concert harp

    OpenAIRE

    Bell, Alexander J.

    1988-01-01

    This thesis is a report of acoustical research on the concert harp. The harp has an established place in the symphony orchestra and is reacquiring its role as a solo chamber instrument that it had before the development of the modern piano. As far as can be determined, this is the first doctoral thesis on the concert harp and serves as an introduction to the science of the instrument, The experimental methods employed- holographic interferonietry, input admittance measure...

  4. Orchestration of the Marketing Strategy under Competitive Dynamics

    OpenAIRE

    Rajagopal

    2010-01-01

    Constructing suitable marketing strategy and implementing it effectively is an art and science both like orchestration of a symphony. The discussion in this paper blends this analogy with the science of marketing demonstrating the levels of strategy development in a competitive marketplace. The paper presents the marketing-mix in contemporary context and argues that performance of a marketing firm can be maximized, when a firm develops a creative marketing strategy and achieves marketing stra...

  5. Dogmas of Understanding in Western Art Music Performance

    OpenAIRE

    Kaastra, Linda

    2015-01-01

    This paper presents an exploration of the ontological shift from musical materials (i.e. melody, harmony, rhythm, texture, timbre, register) to activities in music performance analysis. The “dogmas” extend Herbert H. Clark’s conceptual framework for the study of joint activity in language use to explore music performance in the WAM tradition. A systematic analysis of London Symphony Orchestra masterclasses examines the basic mechanisms of music making in four main areas: representation, audie...

  6. 'n Esteties-kreatiewe herinterpretasie van Pieter en die Wolf deur Sergey Prokofiëf / Elma de Kock

    OpenAIRE

    De Kock, Elma

    2015-01-01

    Peter and the Wolf (1936) is a transmedial work based on a Russian fairy tale composed and written by Sergey Prokofiev . Prokofiev’s purpose with the work was amongst others to introduce children to the instruments of the symphony orchestra. This study examines the possibility of creating a new Afrikaans versification of the text in order to introduce this work to Afrikaans-speaking children. The creative product of the research consists of a picture book and a corresponding so...

  7. Návštěvnost koncertů vážné hudby mladými posluchači

    OpenAIRE

    Žáčková, Kristýna

    2014-01-01

    This thesis is analysing attendance at classical music concerts by young people. First, therefore theoretical part is about marketing and specifics of marketing in arts. Furthermore comparison of two Prague wellknown orchestras, the Prague Symphony Orchestra and the PKF-Prague Philharmonia, and their financial and marketing situation is included. The second part which is practical is dedicated to the experiment of dependence of attandance at classical concerts on age, which was made by quanti...

  8. The Music and the Astronomy

    CERN Document Server

    Caballero, J A; Caballero, I

    2008-01-01

    What do Brian May (the Queen's lead guitarist), William Herschel and the Jupiter Symphony have in common? And a white dwarf, a piano and Lagartija Nick? At first glance, there is no connection between them, nor between the Music and the Astronomy. However, there are many revealing examples of musical Astronomy and astronomical Music. This four-page proceeding describes the sonorous poster that we showed during the VIII Scientific Meeting of the Spanish Astronomical Society.

  9. Arts Management - marketingová strategie symfonického tělesa (Filharmonie mladých Praha)

    OpenAIRE

    Fröhlich, Vojtěch

    2009-01-01

    Goal of this diploma thesis is to create a marketing strategy of the Prague Youth Philharmonic symphony orchestra including marketing concept definition, audience research and marketing communication project. The marketing strategy proceeds from internal and external SWOT analysis of the subject. Theoretical part of the thesis deals with classical marketing theory and its use in arts management praxis. It focuses on strategic marketing and its instruments.

  10. Manhattan Woody'ego Allena. Poetyka Introdukcji

    OpenAIRE

    Hendrykowski, Marek

    2013-01-01

    Marek Hendrykowski’s innovative study on the four-minute opening sequence to Manhattan analyses one of the most beautiful introductions in the history of world cinema. Its subtle simultaneous construction based on European and American traditions and key canonical texts of 20th-century art: Walther Ruttmann’s Berlin: Symphony of the City, John Dos Passos’s Manhattan Transfer and George Gershwin’s Blue Rapsody. A semiotic apparatus has been included, along with deep explanatory commentaries an...

  11. Trinity (for Expanded Orchestra)

    OpenAIRE

    Winokur, Robert Michael

    2011-01-01

    Trinity is a large-scale piece of program music for a symphony orchestra expanded to include two electric guitars (doubling on acoustic guitar), piano (doubling on Fender Rhodes Electric Piano), electric bass guitar and drumset. The main philosophical impetus for this piece is the programmatic depiction (in the manner of a tone poem) of a concept which is based on and combines archetypal characters drawn primarily from literary sources. This dissertation is titled Trinity and uses the thesi...

  12. 5. Orchestral Works

    OpenAIRE

    Omojola, Bode

    2013-01-01

    There are only a few European-type orchestras in Nigeria. The most outstanding of them are the Apostolic Faith Orchestras in Ibadan and Lagos. Because symphony orchestras are not the norm in Nigeria, composers often prefer to write works for solo instruments, chamber orchestra and choirs, which can be more easily performed; and it is not surprising that those orchestral works written are normally commissioned. Like the piano works discussed in the last chapter, the objective of fusing traditi...

  13. Erich Wolfgang Korngold. Orchestration in Opera and Film

    OpenAIRE

    2002-01-01

    In this thesis the orchestral techniques of the late romantic composer Erich Wolfgang Korngold (1897-1957) are investigated. The aim is to approach an understanding of how the composer has established the musical fabric for the symphony orchestra. This gives a further understanding of why the music sounds as it does. The procedure of this investigation is entirely based on analysis of scores in relation to the actual sound. Erich Wolfgang Korngold grew up in Vienna in the beginning of the...

  14. Can Music Save Your Life?

    Science.gov (United States)

    Edmundson, Mark

    2012-01-01

    Who hasn't at least once had the feeling of being remade through music? Who is there who does not date a new phase in life to hearing this or that symphony or song? But does music constantly provide revelation--or does it have some other effects, maybe less desirable? For those who teach, the question is especially pressing. Students tend to spend…

  15. Paddling in Music

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    The Ninth Beijing Music Festival and the Fourth Beijing International Symphony Season will be held October 2-29 in Beijing. In order to promote participation, the festival will host various types of interactive activities, making the festival a carnival for people and music fans. The Beijing Music Festival (BMF), established in 1998 and endorsed by the Ministry of Culture of China and the Beijing Municipal Government, has become one of the grandest and most significant annual cultural events in Asia and ...

  16. Uus plaat

    Index Scriptorium Estoniae

    2004-01-01

    Uutest plaatidest Barry White "Love Songs", Charizma "Life in 3D", Toto Cutugno "il treno va...", "Talkin Loud 1990-1994", Delta Goodrem "Innocent Eyes", Astrud Gilberto "Astrud For Lovers", "Groove Is In The Heart", "The Last Samurai", Patricia Kaas "Sexe & Fort", Norah Jones "Feels Like Home", LeAnn Rimes "The Best Of", "Kumad Eesti hitid 2004", Thursday "War All The Time", Damageplan "New Found Power", Deep Purplr "Purpendicular", "Trance Allstars", Joseph Haydn "Symphonies 1-104", "Takorautaa", "DJ Esko. Setti2"

  17. SEMIOTIC MOTIVES IN Y. YEVTUSHENKO’S POEM “MUM AND THE NEUTRON BOMB” Culturological Notes

    OpenAIRE

    Inna KALITA

    2014-01-01

    The article presents the analysis of some epochal symbols introduced in Y. Yevtushenko’s poem “Mum and the Neutron Bomb” (1982). Creative approaches and their realization made by the author are shown regarding the common course of the 60’s traditions which the author was outstandingly following. The variety of perspectives and the specifics of expression means allow to compare the poem with a symphony. Semiotic approach enables the analysis of symbols introduced considering the epochal co...

  18. Strawinskys Transformation des Urbanen

    OpenAIRE

    Monika Woitas

    2010-01-01

    After 1900 there were new technical inventions like cars, aeroplanes, or locomotives on the one hand, crowded streets and factories on the other, which fundamentally changed the experience of space and time. Simultaneity, motor activity, and montage replaced traditional structures and demanded new modes of perception. Linear development as known in classical drama as well as in symphony or opera appeared increasingly anachronistic. Life at its core was now kinetic and marked by machine-like ‚...

  19. Taking Up the Baton

    Institute of Scientific and Technical Information of China (English)

    ZHOU XIAOYAN

    2010-01-01

    @@ World-famous French conductor Michel Plasson,who led the Orchestre du Capitole de Toulouse for 35 years until 2003,was appointed the principal conductor of the China National Symphony Orchestra(CNSO). During his one-year term,lasson plans to present 10 concerts. Plasson made his first appearance in his new position at the National Center for the Performing Arts(NCPA)in Beijing on March 14,winning great acclaims.

  20. Goldenhar Syndrome in an Infant of Diabetic Mother

    Directory of Open Access Journals (Sweden)

    Manizheh Mostafa Gharehbaghi

    2010-03-01

    Full Text Available Background:Goldenhar syndrome (oculoauriculovertebral dysplasia is a rare congenital anomaly with unknown etiology and consists of non accidental association of hemifacial microsomia, auricular anomalies, epibulbar dermoid and vertebral anomalies. Although some malformations are more frequent in infants of diabetic mothers, developmental defects of first and second branchial arch is not a common finding in these patients. Case Presentation:We report a female case of Goldenhar syndrome in a newborn infant of a diabetic mother (IDM. Follow up of this patient after 6 months showed normal neurodevelopment and no evidence of hearing loss. She had developed epibulbar dermoid tumor in her right eye.Conclusion:It is necessary to evaluate IDM for presence of anomalies implying oculoauriculo-vertebral dysplasia.

  1. Goldenhar Syndrome in an Infant of Diabetic Mother

    Directory of Open Access Journals (Sweden)

    Manizheh Mostafa Gharehbaghi

    2010-03-01

    Full Text Available Background:Goldenhar syndrome (oculoauriculovertebral dysplasia is a rare congenital anomaly with unknown etiology and consists of non accidental association of hemifacial microsomia, auricular anomalies, epibulbar dermoid and vertebral anomalies. Although some malformations are more frequent in infants of diabetic mothers, developmental defects of first and second branchial arch is not a common finding in these patients. Case Presentation:We report a female case of Goldenhar syndrome in a newborn infant of a diabetic mother (IDM. Follow up of this patient after 6 months showed normal neurodevelopment and no evidence of hearing loss. She had developed epibulbar dermoid tumor in her right eye. Conclusion:It is necessary to evaluate IDM for presence of anomalies implying oculoauriculo-vertebral dysplasia.

  2. Telecommunications issues of intelligent database management for ground processing systems in the EOS era

    Science.gov (United States)

    Touch, Joseph D.

    1994-01-01

    Future NASA earth science missions, including the Earth Observing System (EOS), will be generating vast amounts of data that must be processed and stored at various locations around the world. Here we present a stepwise-refinement of the intelligent database management (IDM) of the distributed active archive center (DAAC - one of seven regionally-located EOSDIS archive sites) architecture, to showcase the telecommunications issues involved. We develop this architecture into a general overall design. We show that the current evolution of protocols is sufficient to support IDM at Gbps rates over large distances. We also show that network design can accommodate a flexible data ingestion storage pipeline and a user extraction and visualization engine, without interference between the two.

  3. Development of isotope dilution gamma-ray spectrometry for plutonium analysis

    Energy Technology Data Exchange (ETDEWEB)

    Li, T.K.; Parker, J.L. (Los Alamos National Lab., NM (United States)); Kuno, Y.; Sato, S.; Kurosawa, A.; Akiyama, T. (Power Reactor and Nuclear Fuel Development Corp., Tokai, Ibaraki (Japan))

    1991-01-01

    We are studying the feasibility of determining the plutonium concentration and isotopic distribution of highly radioactive, spent-fuel dissolver solutions by employing high-resolution gamma-ray spectrometry. The study involves gamma-ray plutonium isotopic analysis for both dissolver and spiked dissolver solution samples, after plutonium is eluted through an ion-exchange column and absorbed in a small resin bead bag. The spike is well characterized, dry plutonium containing {approximately}98% of {sup 239}Pu. By using measured isotopic information, the concentration of elemental plutonium in the dissolver solution can be determined. Both the plutonium concentration and the isotopic composition of the dissolver solution obtained from this study agree well with values obtained by traditional isotope dilution mass spectrometry (IDMS). Because it is rapid, easy to operate and maintain, and costs less, this new technique could be an alternative method to IDMS for input accountability and verification measurements in reprocessing plants. 7 refs., 4 figs., 4 tabs.

  4. Efficient Approach To Discover Novel Agrochemical Candidates: Intermediate Derivatization Method.

    Science.gov (United States)

    Liu, Changling; Guan, Aiying; Yang, Jindong; Chai, Baoshan; Li, Miao; Li, Huichao; Yang, Jichun; Xie, Yong

    2016-01-13

    Intensive competition of intellectual property, easy development of agrochemical resistance, and stricter regulations of environmental concerns make the successful rate for agrochemical discovery extremely lower using traditional agrochemical discovery methods. Therefore, there is an urgent need to find a novel approach to guide agrochemical discovery with high efficiency to quickly keep pace with the changing market. On the basis of these situations, here we summarize the intermediate derivatization method (IDM) between conventional methods in agrochemicals and novel ones in pharmaceuticals. This method is relatively efficient with short time in discovery phase, reduced cost, especially good innovated structure, and better performance. In this paper, we summarize and illustrate "what is the IDM" and "why to use" and "how to use" it to accelerate the discovery of new biologically active molecules, focusing on agrochemicals. Furthermore, we display several research projects in our novel agrochemical discovery programs with improved success rate under guidance of this strategy in recent years. PMID:25517210

  5. Cloud Computing: A study of cloud architecture and its patterns

    Directory of Open Access Journals (Sweden)

    Mandeep Handa,

    2015-05-01

    Full Text Available Cloud computing is a general term for anything that involves delivering hosted services over the Internet. Cloud computing is a paradigm shift following the shift from mainframe to client–server in the early 1980s. Cloud computing can be defined as accessing third party software and services on web and paying as per usage. It facilitates scalability and virtualized resources over Internet as a service providing cost effective and scalable solution to customers. Cloud computing has evolved as a disruptive technology and picked up speed with the presence of many vendors in cloud computing space. The evolution of cloud computing from numerous technological approaches and business models such as SaaS, cluster computing, high performance computing, etc., signifies that the cloud IDM can be considered as a superset of all the corresponding issues from these paradigms and many more. In this paper we will discuss Life cycle management, Cloud architecture, Pattern in Cloud IDM, Volatility of Cloud relations.

  6. Determination of Ni, Cu, Pb concentration in the freeze dried urine

    International Nuclear Information System (INIS)

    The method of determining Ni, Cu and Pb in urine with isotope dilution mass spectrometry (IDMS) is described. First, the concentrations of the enriched isotope solutions of 62Ni, 65Cu and 207Pb are determined with the standard solutions of Ni, Cu and Pb as spikes. Then, the contents of Ni, Cu and Pb in the freeze dried urine are determined by IDMS with the enriched isotope solutions as spikes. The experimental results show that the contents (ω) of Ni, Cu and Pb in the freeze dried urine are (0.309 +-0.004) x 10-6, (0.442 +- 0.013) x 10-6, (0.100 +- 0.004) x 10-6, respectively

  7. KEY COMPARISON: Final report on key comparison CCQM-K30: Determination of lead in wine

    Science.gov (United States)

    Hearn, Ruth; Santamaria-Fernandez, Rebeca; Sargent, Mike

    2008-01-01

    The CCQM-K30 key comparison was organized by the Inorganic Analysis Working Group (IAWG) of the CCQM to test the capabilities of national metrological institutes (NMIs) to measure the lead content of wine at the ~3 ng/g level. LGC designed and coordinated the study with the samples being prepared and distributed by Fundacion Chile. Eleven NMIs participated in the key comparison, nine of whom used isotope dilution, one used ICP-MS with external calibration and another used GF-AAS with external calibration. The two laboratories who did not use IDMS, subsequently reported technical difficulties and were therefore not used in the calculation of the KCRV. The agreement among the laboratories using IDMS was excellent as evidenced by the small values for both the equivalence statements (Di reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).

  8. Approach for domestic preparation of standard material (LSD spike) for isotope dilution mass spectrometry

    International Nuclear Information System (INIS)

    The accountancy analysis of the nuclear fuel material at Plutonium Fuel Development Center of JAEA is performed by isotope dilution mass spectrometry (IDMS; Isotope Dilution Mass Spectrometry). IDMS requires the standard material called LSD spike (Large Size Dried spike) which is indispensable for the accountancy in the facilities where the nuclear fuel materials are handled. Although the LSD spike and Pu source material have been supplied from foreign countries, the transportation for such materials has been getting more difficult recently. This difficulty may affect the operation of nuclear facilities in the future. Therefore, research and development of the domestic LSD spike and base material has been performed at JAEA. Certification for such standard nuclear materials including spikes produced in Japan is being studied. This report presents the current status and the future plan for the technological development. (author)

  9. NOVEL CONTEXT-AWARE CLUSTERING WITH HIERARCHICAL ADDRESSING (CCHA) FOR THE INTERNET OF THINGS (IoT)

    DEFF Research Database (Denmark)

    Mahalle, Parikshit N.; Prasad, Neeli R.; Prasad, Ramjee

    2013-01-01

    As computing technology becomes more tightly coupled into dynamic and mobile world of the Internet of Things (IoT), security mechanism becomes more stringent, less flexible and intrusive. Scalability issue in the IoT makes Identity Management (IdM) of ubiquitous things more challenging. Forming ad......-hoc network, interaction between these nomadic devices to provide seamless service extend the need of new identi-ties to the things, addressing and IdM in the IoT. New identities and identifier format to alleviate the perfor-mance issue is introduced in this paper. This paper pre-sents novel Context......-aware Clustering with Hierarchical Addressing (CCHA) scheme for the things with new identifier format. Simulation results shows that CCHA achieves better performance with less energy expendi-ture, less end-to-end delay and more throughput. Results also show that CCHA significantly reduces the failure probability...

  10. Prototype of Intrusion Detection Model using UML 5.0 and Forward Engineering

    Directory of Open Access Journals (Sweden)

    Muthaiyan MADIAJAGAN,

    2011-01-01

    Full Text Available In this paper we are using UML (Unified Modeling Language which is the blueprint language between the programmers, analysts, and designer’s for easy representation of pictures or diagrammatic notation with some textual data. Here we are using UML 5.0 to show “prototype of the Intrusion Detection Model” and by explaining it by combining various parts by drawing various UML diagrams such as Use cases and Activity diagrams and Class Diagram using which we show forward engineering using the class diagram of the IDM( Intrusion Detection Model. IDM is a device or software that works on detecting malicious activities by unauthorized users that can cause breach to the security policy within a network.

  11. Methods for implementing Building Information Modeling and Building Performance Simulation approaches

    DEFF Research Database (Denmark)

    Mondrup, Thomas Fænø

    , Engineering, Construction, and Facility Management (AEC/ FM) communication, and (b) BPS as a platform for early-stage building performance prediction. The second is to develop (a) relevant AEC/FM communication support instruments, and (b) standardized BIM and BPS execution guidelines and information exchange...... and standardized exchange formats, and in-depth preparation and training of AEC/FM project participants are given a high priority. It is essential that this preparation and training are supported by common BIM standards and execution guidelines. Thesis studies also showed that BPS approaches have the potential...... is created by selecting the specific IDM Packages required for the specific AEC/FM project. In this approach, the IDM Project Plan can help communicate the overall scope of the AEC/FM project, processes to be carried out, organizational interactions, and required information exchanges. In this thesis...

  12. Certification of mercury in acrylonitrile butadiene styrene by using isotope dilution mass spectrometry

    International Nuclear Information System (INIS)

    Under the framework of a co-certification system for the development of Certified Reference Materials (CRMs) among China, Japan and Korea, the 1st co-certification campaign of mercury in acrylonitrile butadiene styrene (ABS) for Japanese CRMs was taken. In this campaign isotope dilution mass spectrometry (IDMS) was used. First, all abundances of Hg in spike 202Hg, CRM and ABS were analyzed by MC-ICP-MS before the certification. Then the concentrations of 202Hg and Hg in ABS were determined with IDMS by Q-ICP-MS. A new procedure to reduce memory effect was used. first, dilute with 5 μg/g Au solution for 1 min; then, 5 μg/g EDTA solution for 2 min. The results accord to each other very well and this implies that the co-certification system can run swimmingly. (authors)

  13. Syntelencephaly in an infant of a diabetic mother.

    Science.gov (United States)

    Robin, N H; Ko, L M; Heeger, S; Muise, K L; Judge, N; Bangert, B A

    1996-12-30

    Here we report on an infant of a diabetic mother (IDM) with midline interhemispheric "fusion" (MIF), or syntelencephaly. This is a rare anomaly characterized by segmental failure of cleavage of the cerebral hemispheres and other brain structures in the posterior frontal and parietal regions, with a normal interhemispheric fissure anterior and posterior to the "fused" region. While there is obvious overlap with holoprosencephaly (HPE), this condition differs from HPE in that the midline "fusion" in MIF is complete but segmental, while the structural brain anomalies seen in the HPE spectrum progress smoothly in severity in a posterior to anterior "fusion." However, while it is apparent that there are key distinctions between MIF and HPE, in all likelihood they arise from a similar pathogenetic mechanisms. We therefore suggest that MIF is a distinct variant of the HPE spectrum of midline brain anomalies. Given the known increased incidence of HPE in IDMs, MIF is likely a maternal diabetes-associated malformation. PMID:8989462

  14. THE VERTICAL THERMAL STRUCTURE OF THE INDIAN OCEAN DIPOLE MODE FROM WOCE DATA

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The Dipole Mode in tropical Indian Ocean (DMI) is a newly verified independent internal mode of atmosphere-ocean system in Indian Ocean. Its surface manifestation is illustrated in detail with the aid of the historical data sets. But relatively few is known about its vertical characteristics. Here the vertical thermal structure of DMI is analyzed using the newly released WOCE GLOBAL DATA (V2.0). Attention is focused on the comparison of the abnormal upper ocean thermal structure along one section with the normal state in year 1990 respectively in two cases: in year 1994 when there was IDM but no E1 Nino and in year 1997 when there were DMI and also E1 Nino. This may shed light on the further theoretical and numerical study of IDM.

  15. Single Thing Sign On Identity Management for Internet of Things

    DEFF Research Database (Denmark)

    Zdravkova, Vanya; Mihaylov, Mihail Rumenov; Mihovska, Albena Dimitrova;

    2016-01-01

    —Within the context of heterogeneous Internet of Things (IoT) network driven by Machine-to-Machine (M2M) communications there is a need for a proper user identification and Identity Management (IdM) mechanisms which to involve all of the objects in the IoT. The paper addresses user identification...... by proposing Single Thing Sign On (STSO) IdM architecture for IoT, where the end-user is in the middle of a user-centered services ecosystem. The proposed scheme enables user recognition and services access only by identification of one of the “things” related to the user such as personal computing devices...

  16. Hydrogen generation during treatment of simulated high-level radioactive waste with formic acid

    Energy Technology Data Exchange (ETDEWEB)

    Ritter, J.A.; Zamecnik, J.R.; Hsu, C.W.

    1992-05-01

    The Integrated Defense Waste Processing Facility (DWPF) Melter System (IDMS), operated by the Savannah River Laboratory, is a one-fifth scale pilot facility used in support of the start-up and operation of the Department of Energy`s DWPF. Five IDMS runs determined the effect of the presence of noble metals in HLW sludge on the H{sub 2} generation rate during the preparation of melter feed with formic acid. Overall, the results clearly showed that H{sub 2} generation in the DWPF SRAT could, at times, exceed the lower flammable limit of H{sub 2} in air (4 vol%), depending on such factors as offgas generation and air inleakage of the DWPF vessels. Therefore, the installation of a forced air purge system and H{sub 2} monitors were recommended to the DWPF to control the generation of H{sub 2} during melter feed preparation by fuel dilution.

  17. Hydrogen generation during treatment of simulated high-level radioactive waste with formic acid

    Energy Technology Data Exchange (ETDEWEB)

    Ritter, J.A.; Zamecnik, J.R.; Hsu, C.W.

    1992-01-01

    The Integrated Defense Waste Processing Facility (DWPF) Melter System (IDMS), operated by the Savannah River Laboratory, is a one-fifth scale pilot facility used in support of the start-up and operation of the Department of Energy's DWPF. Five IDMS runs determined the effect of the presence of noble metals in HLW sludge on the H{sub 2} generation rate during the preparation of melter feed with formic acid. Overall, the results clearly showed that H{sub 2} generation in the DWPF SRAT could, at times, exceed the lower flammable limit of H{sub 2} in air (4 vol%), depending on such factors as offgas generation and air inleakage of the DWPF vessels. Therefore, the installation of a forced air purge system and H{sub 2} monitors were recommended to the DWPF to control the generation of H{sub 2} during melter feed preparation by fuel dilution.

  18. NODC Report: France

    OpenAIRE

    2000-01-01

    SISMER (Systèmes d'Informations Scientifiques pour la Mer) was created in 1990. Since 1997 it belongs to the Computer, Informatics and Marine Data (IDM) Department of the Marine Technology & Information System Directorship (TMSI) of IFREMER. It participates in the "Information Systems for Oceanography" programme of the institute key action "Major Equipment for Oceanography". As defined in its missions, it designs and operates scientific information systems and databases for national and inter...

  19. NODC Report for France

    OpenAIRE

    2003-01-01

    SISMER (Systèmes d'Informations Scientifiques pour la Mer) belongs to the Computer, Informatics and Marine Data (IDM) Department of the Marine Technology & Information System Directorship (TMSI) of IFREMER. It participates in the "Information Systems for Oceanography" programme of the institute key action "Major Equipment for Oceanography". As defined in its missions, it designs and operates scientific information systems and databases for national and international projects in the marine ...

  20. Quantification of optimal electricity cost risk reduction for a South African gold mining company

    OpenAIRE

    Van der Zee, L.F.; Pelzer, R.; Bolt, G.

    2014-01-01

    Electricity cost risks such as carbon tax, ECS and unavoidable tariff increases threaten the financial wellbeing of South African gold mines. Some of these proposed cost risks are however not enforced as yet. However, once approved, they could result in thousands of jobs being lost. The Eskom Integrated Demand Management (IDM) funding program for industrial projects has also been put on hold. With more than 97 large (367 MW total) projects already implemented on South African gold mines, thes...

  1. Multi-objective water allocation in the Alqueva Region

    OpenAIRE

    R. Fragoso; Bushenkov, V.; Marques, C. A. F.

    2010-01-01

    Alqueva dam in the Alentejo Region was developed to solve water scarcity in the South ofPortugal and to ensure pennanent availability ofwater for household and industrial consumption, irrigation, production of electric energy, ecological and environrnental purposes. Competition among some ofthese multiple water uses requires an integrated management framework. This paper uses Interactive Decision Maps (IDM) technique to explore and achieve efficient and equitable water alloc...

  2. Analysing the effect of DSM projects at South African cement factories / Johannes Paulus Spangenberg

    OpenAIRE

    Spangenberg, Johannes Paulus

    2015-01-01

    In any developing country an increasingly higher demand for electricity supply exists. South Africa experienced load shedding during late 2007 and early 2008 and again in 2014 due to a supply shortfall. New power stations are being built to increase the capacity of the national power grid. However this is a lengthy process. Demand Side Management (DSM) was adopted by Eskom’s Integrated Demand Management (IDM) division. DSM is a short-term solution to stabilise the national grid in South Af...

  3. Isotope dilution mass spectrometry for quantitative elemental analysis of powdered samples by radiofrequency pulsed glow discharge time of flight mass spectrometry.

    Science.gov (United States)

    Alvarez-Toral, Aitor; Fernandez, Beatriz; Malherbe, Julien; Claverie, Fanny; Molloy, John L; Pereiro, Rosario; Sanz-Medel, Alfredo

    2013-10-15

    In recent years particular effort is being devoted to the development of pulsed glow discharges (PGDs) for mass spectrometry because this powering operation mode could offer important ionization analytical advantages. However, the capabilities of radiofrequency (RF) PGD coupled to a time of flight mass spectrometry (ToFMS) for accurate isotope ratio measurements have not been demonstrated yet. This work is focused on investigating different time positions along the pulse profile for the accurate measurement of isotope ratios. As a result, a method has been developed for the direct and simultaneous multielement determination of trace elements in powdered geological samples by RF-PGD-ToFMS in combination with isotope dilution mass spectrometry (IDMS) as an absolute measurement method directly traceable to the International System of Units. Optimized operating conditions were 70 W of applied radiofrequency power, 250 Pa of pressure, 2 ms of pulse width and 4 ms of pulse period, being argon the plasma gas used. To homogeneously distribute the added isotopically-enriched standards, lithium borate fusion of powdered solid samples was used as sample preparation approach. In this way, Cu, Zn, Ba and Pb were successfully determined by RF-PGD-ToF(IDMS) in two NIST Standard Reference Materials (SRM 2586 and SRM 2780) representing two different matrices of geological interest (soil and rock samples). Cu, Zn, Ba and Pb concentrations determined by RF-PGD-ToF(IDMS) were well in agreement with the certified values at 95% confidence interval and precisions below 12% relative standard deviation were observed for three independent analyses. Elemental concentrations investigated were in the range of 81-5770 mg/kg, demonstrating the potential of RF-PGD-ToF(IDMS) for a sensitive, accurate and robust analysis of powdered samples. PMID:24054645

  4. The inert doublet model: a new archetype of WIMP dark matter?

    International Nuclear Information System (INIS)

    The Inert Doublet Model (IDM) is a two doublet extension of the Higgs-Brout-Englert sector of the Standard Model with a Z2 symmetry in order to prevent FCNC. If the Z2 symmetry is not spontaneously broken, the lightest neutral extra scalar is a dark matter candidate. We briefly review the phenomenology of the model, emphasizing its relevance for the issue of Electroweak Symmetry Breaking (EWSB) and the prospects for detection of dark matter

  5. Traffic-flow simulation

    OpenAIRE

    OMAHEN, ANDRAŽ

    2015-01-01

    This diploma thesis presents the behavior of program, which uses the traffic light enhanced transport network to simulate the traffic flow of vehicles that behave according to the IDM model. We upgraded the program to allow, for the given network, to optimize the traffic flow. Because of the overwhelming problem of road closures or their rearrangement, we added a graphical user interface with which a user can create or modify the road network to observe changes in traffic. The objective of...

  6. Morbidity and mortality amongst infants of diabetic mothers admitted into a special care baby unit in Port Harcourt, Nigeria

    OpenAIRE

    Onubogu Uche C; Jaja Tamunopriye; Opara Peace I

    2010-01-01

    Abstract Background Infants born to diabetic women have certain distinctive characteristics, including large size and high morbidity risks. The neonatal mortality rate is over five times that of infants of non diabetic mothers and is higher at all gestational ages and birth weight for gestational age (GA) categories. The study aimed to determine morbidity and mortality pattern amongst infants of diabetic mothers (IDMS) admitted into the Special Care Baby Unit of University of Port Harcourt Te...

  7. Instruction Design Model for Self-Paced ICT System E-Learning in an Organization

    OpenAIRE

    Ridi Ferdiana; Obert Hoseanto

    2012-01-01

    Adopting an Information Communication and Technology (ICT) system in an organization is somewhat challenging. User diversity, heavy workload, and different skill gap make the ICT adoption process slower. This research starts from a condition that a conventional ICT learning through short workshop and guidance book is not working well. This research proposes a model called ICT instruction design model (ICT-IDM). This model provides fast track learning through integration between multimedia lea...

  8. Development of a database system for mapping insertional mutations onto the mouse genome with large-scale experimental data

    OpenAIRE

    Yang, Wenwei; Jin, Ke; Xie, Xing; Li, Dongsheng; Yang, Jigang; Wang, Li; Gu, Ning; Zhong, Yang; Sun, Ling V.

    2009-01-01

    Background Insertional mutagenesis is an effective method for functional genomic studies in various organisms. It can rapidly generate easily tractable mutations. A large-scale insertional mutagenesis with the piggyBac (PB) transposon is currently performed in mice at the Institute of Developmental Biology and Molecular Medicine (IDM), Fudan University in Shanghai, China. This project is carried out via collaborations among multiple groups overseeing interconnected experimental steps and gene...

  9. Indomethacin nanocrystals prepared by different laboratory scale methods: effect on crystalline form and dissolution behavior

    Energy Technology Data Exchange (ETDEWEB)

    Martena, Valentina; Censi, Roberta [University of Camerino, School of Pharmacy (Italy); Hoti, Ela; Malaj, Ledjan [University of Tirana, Department of Pharmacy (Albania); Di Martino, Piera, E-mail: piera.dimartino@unicam.it [University of Camerino, School of Pharmacy (Italy)

    2012-12-15

    The objective of this study is to select very simple and well-known laboratory scale methods able to reduce particle size of indomethacin until the nanometric scale. The effect on the crystalline form and the dissolution behavior of the different samples was deliberately evaluated in absence of any surfactants as stabilizers. Nanocrystals of indomethacin (native crystals are in the {gamma} form) (IDM) were obtained by three laboratory scale methods: A (Batch A: crystallization by solvent evaporation in a nano-spray dryer), B (Batch B-15 and B-30: wet milling and lyophilization), and C (Batch C-20-N and C-40-N: Cryo-milling in the presence of liquid nitrogen). Nanocrystals obtained by the method A (Batch A) crystallized into a mixture of {alpha} and {gamma} polymorphic forms. IDM obtained by the two other methods remained in the {gamma} form and a different attitude to the crystallinity decrease were observed, with a more considerable decrease in crystalline degree for IDM milled for 40 min in the presence of liquid nitrogen. The intrinsic dissolution rate (IDR) revealed a higher dissolution rate for Batches A and C-40-N, due to the higher IDR of {alpha} form than {gamma} form for the Batch A, and the lower crystallinity degree for both the Batches A and C-40-N. These factors, as well as the decrease in particle size, influenced the IDM dissolution rate from the particle samples. Modifications in the solid physical state that may occur using different particle size reduction treatments have to be taken into consideration during the scale up and industrial development of new solid dosage forms.

  10. 痕量铀、钚样品中同位素比值测定

    Institute of Scientific and Technical Information of China (English)

    龙开明; 付中华; 毛欣根; 邢丕峰; 孟繁本; 贾宝亭

    2000-01-01

    The method about determination isotope ratio in lng Uranium and 100pg Plutonium samples has been developed by using IDMS with high isotope abundance spike 233U and 242Pu. The isotope ratio uncertainty in lng Uranium and 100pg Plutonium samples are about ±20%, and it was mainly contributed by isotope ratio uncertainty of blend and spike. The blend and spike contamination from natural Uranium must be care in experiments.

  11. Indomethacin nanocrystals prepared by different laboratory scale methods: effect on crystalline form and dissolution behavior

    International Nuclear Information System (INIS)

    The objective of this study is to select very simple and well-known laboratory scale methods able to reduce particle size of indomethacin until the nanometric scale. The effect on the crystalline form and the dissolution behavior of the different samples was deliberately evaluated in absence of any surfactants as stabilizers. Nanocrystals of indomethacin (native crystals are in the γ form) (IDM) were obtained by three laboratory scale methods: A (Batch A: crystallization by solvent evaporation in a nano-spray dryer), B (Batch B-15 and B-30: wet milling and lyophilization), and C (Batch C-20-N and C-40-N: Cryo-milling in the presence of liquid nitrogen). Nanocrystals obtained by the method A (Batch A) crystallized into a mixture of α and γ polymorphic forms. IDM obtained by the two other methods remained in the γ form and a different attitude to the crystallinity decrease were observed, with a more considerable decrease in crystalline degree for IDM milled for 40 min in the presence of liquid nitrogen. The intrinsic dissolution rate (IDR) revealed a higher dissolution rate for Batches A and C-40-N, due to the higher IDR of α form than γ form for the Batch A, and the lower crystallinity degree for both the Batches A and C-40-N. These factors, as well as the decrease in particle size, influenced the IDM dissolution rate from the particle samples. Modifications in the solid physical state that may occur using different particle size reduction treatments have to be taken into consideration during the scale up and industrial development of new solid dosage forms.

  12. Dissecting the genetic structure and admixture of four geographical Malay populations

    OpenAIRE

    Lian Deng; Boon-Peng Hoh; Dongsheng Lu; Woei-Yuh Saw; Rick Twee-Hee Ong; Anuradhani Kasturiratne; H Janaka de Silva; Bin Alwi Zilfalil; Norihiro Kato; Wickremasinghe, Ananda R; Yik-Ying Teo; Shuhua Xu

    2015-01-01

    The Malay people are an important ethnic composition in Southeast Asia, but their genetic make-up and population structure remain poorly studied. Here we conducted a genome-wide study of four geographical Malay populations: Peninsular Malaysian Malay (PMM), Singaporean Malay (SGM), Indonesian Malay (IDM) and Sri Lankan Malay (SLM). All the four Malay populations showed substantial admixture with multiple ancestries. We identified four major ancestral components in Malay populations: Austrones...

  13. Semantic Integration of Identity Data Repositories

    OpenAIRE

    Emig, Christian; Langer, Kim; Biermann, Jürgen; Abeck, Sebastian

    2007-01-01

    With the continuously growing number of distributed and heterogeneous IT systems there is the need for structured and efficient identity management (IdM) processes. This implies that new users are created once and then the information is distributed to all applicable software systems same as if changes on existing user objects occur. The central issue is that there is no generally ac-cepted standard for handling this information distribution because each system has its own internal representa...

  14. Security for Future Networks : a Prospective Study of AAIs

    OpenAIRE

    Aissaoui, Hassane; URIEN, Pascal; Pujolle, Guy; Joni Da Silva, Fraga; Davi Da Silva, Böger

    2013-01-01

    The future Internet will rely heavily on virtualization and cloud networking. The project Security for Future Networks proposes the design of a framework providing secure identification and authentication, secure data transfer and secure virtualized infrastructure. In this paper, we present a comparative study should examine some models and frameworks of Identity Management (IdM). Initially, we had identified OpenID, Higgins and Shibboleth frameworks as those providing facilities that are the...

  15. Development of a Spiritually Based Educational Intervention to Increase Informed Decision Making for Prostate Cancer Screening Among Church-Attending African American Men

    OpenAIRE

    Holt, Cheryl L.; Wynn, Theresa A.; Southward, Penny; Litaker, Mark S.; Jeames, Sanford; Schulz, Emily

    2009-01-01

    One way of developing culturally relevant health communication in the African American church setting is to develop spiritually based interventions, in which the health message is framed by relevant spiritual themes and scripture. In this article we describe the development of a community health advisor (CHA)-led intervention aimed at increasing informed decision making (IDM) for prostate cancer screening among church-attending African American men. Full-color print educational booklets were ...

  16. Scalar Dark Matter Candidates in Two Inert Higgs Doublet Model

    CERN Document Server

    Fortes, E C F S; Montaño, J; Pleitez, V

    2014-01-01

    We study a two scalar inert doublet model (IDMS$_3$) which is stabilized by a $S_3$ symmetry. We consider two scenarios: i) two of the scalars in each charged sector are mass degenerated due to a residual $Z_2$ symmetry, ii) there is no mass degeneracy because of the introduction of soft terms that break the $Z_2$ symmetry. We show that both scenarios provide good dark matter candidates for some range of parameters.

  17. Concurrent Systems Engineering in Aerospace: From Excel-based to Model Driven Design

    OpenAIRE

    Schumann, Holger; Wendel, Heinrich; Braukhane, Andy; Berres, Axel; Gerndt, Andreas; Schreiber, Andreas

    2010-01-01

    Concurrent engineering is a modern and very effective discipline of systems engineering. In the European space domain, the European Space Agency is the pioneer in this area and has performed early design studies for 10 years now. The Integrated Design Model (IDM) is still the state of the art in concurrent engineering software environments. It is based on Microsoft Excel, which induces several benefits and drawbacks related to concurrent engineering. The German Aerospace Center has used t...

  18. Antioxidant Enzymes and Certain Trace Elements Values in Infants of Diabetic Mothers

    International Nuclear Information System (INIS)

    Oxidative stress and accumulation of oxygen free radicals is a pathophysiological process leading to disadvantageous outcomes in diabetic pregnancies. Diabetes in pregnancy increases perinatal morbidity and mortality of both mother and her newborn. This study aimed to gain a view of antioxidant defense in the blood of infants of diabetic mothers (IDMs) and to clarify the relation among serum copper (Cu), Zinc (Zn), Selenium (Se) and antioxidant enzymes in these infants. For this reason, 25 infants of diabetic mothers (IDMs) were investigated. Twenty five newborns of healthy mothers served as a control group. Anthropometric and clinical evaluations were assessed in both groups. Laboratory investigations were performed including complete blood picture, direct and total bilirubin, serum Cu, Zn and Se. Erythrocyte superoxide dismutase (E-SOD)and erythrocyte glutathione peroxidase (E-GSHPx) were assisted. This study displayed highly significant reduction in levels of E-SOD and E-GSHPx in IDMs and in the mean serum levels of Cu, Zn and Se as compared to controls. There was a negative significant correlation between serum Zinc and blood glucose, there was a positive correlation between serum copper concentration and both gestational age and length. It also showed a significant positive correlation between GSHPx and both gestational age and Apgar 1, and a significant positive correlation between E-SOD, Apgar 1 and Apgar 5. These results proved that there is a state of oxidative stress in IDMs, therefore, their oxidant and antioxidant status should be carefully considered and appropriate management should be organized during the pregnancy and in the early postnatal period, including antioxidant and micro nutrients supplementation

  19. The development of an intelligent user interface for NASA's scientific databases

    Science.gov (United States)

    Campbell, William J.; Roelofs, Larry H.

    1986-01-01

    The National Space Science Data Center (NSSDC) has initiated an Intelligent Data Management (IDM) research effort which has as one of its components, the development of an Intelligent User Interface (IUI). The intent of the IUI effort is to develop a friendly and intelligent user interface service that is based on expert systems and natural language processing technologies. This paper presents the design concepts, development approach and evaluation of performance of a prototype Intelligent User Interface Subsystem (IUIS) supporting an operational database.

  20. Congenital Heart Diseases in the Newborns of Diabetic Mothers: an Echocardiographic Study

    OpenAIRE

    S Rahimpour; V Modarresi; Behjati, M; MA Behjati

    2011-01-01

    Introduction: Despite the discovery of insulin and current improvement in diabetics care, congenital malformations in diabetics are still more frequent than in the general population. The aim of this study was to identify congenital heart dieases (CHD) in the newborns of diabetic mothers (IDMS). Methods: In our prospective study, color doppler echocardiography was performed in 75 consecutive full- term newborns of diabetic mothers by GE Vivid3 echocardiographic device. Newborns were classifie...

  1. Nitric acid flowsheet with late wash PHA testing

    International Nuclear Information System (INIS)

    This Task Technical Plan outlines the activities to be conducted in the Integrated DWPF Melter System (IDMS) in ongoing support of the Defense Waste Processing Facility (DWPF) Chemical Process Cell (CPC) utilizing the Nitric Acid Flowsheet in the Sludge Receipt and Adjustment Tank (SRAT) and Precipitate Hydrolysis Aqueous (PHA) produced by the Late Wash Flowsheet. The IDMS facility is to be operated over a series of runs (2 to 4) using the Nitric Acid Flowsheet. The PHA will be produced with the Late Wash Flowsheet in the Precipitate Hydrolysis Experimental Facility (PHEF). All operating conditions shall simulate the expected DWPF operating conditions as closely as possible. The task objectives are to perform at least two IDMS runs with as many operating conditions as possible at nominal DWPF conditions. The major purposes of these runs are twofold: verify that the combined Late Wash and Nitric Acid flowsheets produce glass of acceptable quality without additional changes to process equipment, and determine the reproducibility of data from run to run. These runs at nominal conditions will be compared to previous runs made with PHA produced from the Late Wash flowsheet and with the Nitric Acid flowsheet in the SRAT (Purex 4 and Purex 5)

  2. Application of isotope dilution method for measuring bioavailability of organic contaminants sorbed to dissolved organic matter (DOM)

    International Nuclear Information System (INIS)

    Natural waters such as surface water and sediment porewater invariably contain dissolved organic matter (DOM). Association of strongly hydrophobic contaminants (HOCs) with DOM leads to decreased toxicity and bioavailability, but bioavailability of DOM-sorbed HOCs is difficult to measure. Current methods to estimate bioavailability of HOCs in water are based on only the freely dissolved concentration (Cfree). The ignorance of the exchangeable fraction of HOCs sorbed on DOM may result in an underestimation of the toxicity potential of HOCs to aquatic organisms. Here we explore the applicability of an isotope dilution method (IDM) to measuring the desorption fraction of DOM-sorbed pyrene and bifenthrin and determining their exchangeable pool (E) as an approximation of bioavailability. E values, expressed as percentage of the total concentration, ranged between 0.80 and 0.92% for pyrene and 0.74 and 0.85% for bifenthrin, depending primarily on the amount of chemical in the freely dissolved form. However, between 34 and 78% of the DOM-sorbed pyrene was exchangeable. This fraction ranged between 23% and 82% for bifenthrin. The ability of IDM to predict bioavailability was further shown from a significant relationship (r2 > 0.72, P < 0.0001) between E and bioaccumulation into Daphnia magna. Therefore, IDM may be used to improve the bioavailability measurement and risk assessment of HOCs in aquatic systems

  3. Gastrin-releasing peptide receptor antagonist or N-acetylcysteine combined with omeprazol protect against mitochondrial complex II inhibition in a rat model of gastritis.

    Science.gov (United States)

    Rezin, Gislaine T; Petronilho, Fabricia C; Araújo, João H; Gonçalves, Cinara L; Daufenbach, Juliana F; Cardoso, Mariane R; Roesler, Rafael; Schwartsmann, Gilberto; Dal-Pizzol, Felipe; Streck, Emilio L

    2011-03-01

    The pathophysiology of gastritis involves an imbalance between gastric acid attack and mucosal defence. In addition, the gastric mucosal injury results in adenosine triphosphate (ATP) depletion leading to mitochondrial dysfunction. Several studies have shown the association of mitochondrial disorders with gastrointestinal dysfunction. In the present study, we investigated the activity of mitochondrial respiratory chain complexes activity in the stomach of rats with gastritis induced by indomethacin (IDM) and treated with omeprazole (OM), N-acetylcysteine (NAC) and the gastrin-releasing peptide receptor (GRPR) antagonist RC-3095. Adult male Wistar rats were pre-treated for 7 days with OM, NAC, RC-3095, combination of OM plus RC-3095, OM plus NAC and water (control). The animals were then submitted to fasting for 24 hr; IDM was administered. The rats were killed 6 hr later, and the stomachs were used for evaluation of macroscopic damage and respiratory chain activity. Our results showed that complex I and IV activities were not affected by administration of IDM. On the other hand, complex II and III activities were inhibited. In addition, OM plus RC-3095 and OM plus NAC did not reverse complex II activity inhibition. However, the complex III activity inhibition was reversed only with the combined use of OM plus RC-3095 and OM plus NAC. Our results are in agreement with previous studies indicating mitochondrial dysfunction in the pathophysiology of gastrointestinal tract disease and we suggest that GRPR antagonism might be a novel therapeutic strategy in gastritis. PMID:21138529

  4. Application of isotope dilution method for measuring bioavailability of organic contaminants sorbed to dissolved organic matter (DOM)

    Energy Technology Data Exchange (ETDEWEB)

    Delgado-Moreno, Laura, E-mail: laura.delgado@eez.csic.es; Wu, Laosheng; Gan, Jay

    2015-08-15

    Natural waters such as surface water and sediment porewater invariably contain dissolved organic matter (DOM). Association of strongly hydrophobic contaminants (HOCs) with DOM leads to decreased toxicity and bioavailability, but bioavailability of DOM-sorbed HOCs is difficult to measure. Current methods to estimate bioavailability of HOCs in water are based on only the freely dissolved concentration (C{sub free}). The ignorance of the exchangeable fraction of HOCs sorbed on DOM may result in an underestimation of the toxicity potential of HOCs to aquatic organisms. Here we explore the applicability of an isotope dilution method (IDM) to measuring the desorption fraction of DOM-sorbed pyrene and bifenthrin and determining their exchangeable pool (E) as an approximation of bioavailability. E values, expressed as percentage of the total concentration, ranged between 0.80 and 0.92% for pyrene and 0.74 and 0.85% for bifenthrin, depending primarily on the amount of chemical in the freely dissolved form. However, between 34 and 78% of the DOM-sorbed pyrene was exchangeable. This fraction ranged between 23% and 82% for bifenthrin. The ability of IDM to predict bioavailability was further shown from a significant relationship (r{sup 2} > 0.72, P < 0.0001) between E and bioaccumulation into Daphnia magna. Therefore, IDM may be used to improve the bioavailability measurement and risk assessment of HOCs in aquatic systems.

  5. Isotope dilution alpha spectrometry for the determination of plutonium concentration in irradiated fuel dissolver solution : IDAS and R-IDAS

    International Nuclear Information System (INIS)

    The report presents a new technique, Isotope Dilution Alpha Spectrometry (IDAS) and Reverse Isotope Dilution Alpha Spectrometry (R-IDAS) for determining the concentration of plutonium in the irradiated fuel dissolver solution. The method exploits sup(238)Pu in IDAS and sup(239)Pu in R-IDAS as a spike and provides an alternative method to Isotope Dilution Mass Spectrometry (IDMS) which requires enriched sup(242)Pu as a spike. Depending upon the burn-up of the fuel, sup(238)Pu or sup(239)Pu is used as a spike to change the sup(238)Pu/(sup(239)Pu+sup(240)Pu)α activity ratio in the sample by a factor of 10. This change is determined by α-spectrometry on electrodeposited sources using a solid state silicon surface barrier detector coupled to a multichannel analyser. The validity of a simple method based on the geometric progression (G.P.) decrease for the far tail of the spectrum to correct for the tail contribution of sup(238)Pu peak (5.50 MeV) to the low energy sup(239)Pu + sup(240)Pu peak (5.17 MeV) is established. Results for the plutonium concentration on different irradiated fuel dissolver solutions with burn-uo ranging from J,000 to 100,000 MWD/TU are presented and compared with those obtained by IDMS. The values obtained by IDAS or R-IDAS and IDMS agree within 0.5%. (auth.)

  6. Trace analysis of U, Th and other heavy metals in high purity aluminium with isotope dilution mass spectrometry

    International Nuclear Information System (INIS)

    A method for the determination of very low concentrations of U, Th, Fe, Zn, Tl, Cd, Cu and Ag in high purity aluminium with isotope dilution mass spectrometry (IDMS) is developed using a compact and cost-efficient thermal ionization quadrupole mass spectrometer. The detection limits obtained are (in ng/g):U=0.018, Th=0.06, Fe=82, Zn=86, Tl=0.2, Cd=4, Cu=1, Ag=2.6. By this method it is possible to determine the α-emitters U and Th in aluminium down to the sub-ng/g level with good precision of 0.4-10% and 0.5-5%, respectively. The results should also be accurate because IDMS is a reliable analytical method. The dissolution of aluminium is carried out by aqua regia followed by the trace/matrix separation and the isolation of the trace elements by anion exchange chromatography (U, Th, Zn, Tl, Cd), electrodeposition (Cu, Ag) and extraction (Fe). Different aluminium samples are analysed by IDMS and the results are compared with those of other methods. (orig.)

  7. Estimates of in situ digestibility and fibrous compounds in feeds for ruminants

    Directory of Open Access Journals (Sweden)

    Frank Akiyoshi Kuwahara

    2015-08-01

    Full Text Available Current paper assesses the relationship between in situ incubation time, particle size and types of materials on estimates of indigestible fractions of dry matter (iDM and neutral detergent fiber (iNDF in cattle feed and feces. Samples of soybean meal, alfalfa and feces of cattle fed on high concentrated diets were analyzed. The samples were processed in a Wiley mill, with 0.5 and 1.5 mm porosity for food and 1.5 mm for feces, which were packed in 4 × 5 cm F57 bags (Ankon® and nonwoven fabric (100 g m-2 of two brands. The material was divided into two groups, with and without treatment with acetone, and five replications. Samples of each group were incubated in the rumen of a multiparous cow adapted to a 70:30 diet, forage:concentrate diet, for 240 hours. The iDM and iNDF levels were evaluated sequentially to interpret the percentages of undigested material. Data underwent analysis of variance (ANOVA, p < 0.05 and means were compared by Tukey’s test (p < 0.05. Material, size of particles and incubated material affected iDM and iNDF estimates.

  8. Evaluation in situ digestibility of alfalfa in different grinds and textiles

    Directory of Open Access Journals (Sweden)

    Frank Akiyoshi Kuwahara

    2016-01-01

    Full Text Available Indigestible fractions of dry matter (iDM and neutral detergent fiber (iNDF in the feed of ruminants are mainly estimated by in situ incubation time with regard to particle size and textile types. Samples of alfafa, ground into three particle sizes, were analyzed. Samples, processed in a Willey mill with 1.0; 2.0 and 3.0 mm sieve pores, were conditioned in F57 (Ankon®, nonwoven (100 g m-2 and polyester textile bags measuring 4 x 5 cm. Material was divided into 13 incubation periods and 8 replications, and incubated in the rumen of two multiparous cows adapted to a 70:30 diet, roughage:concentrate, respectively, for 288h. iDM and iNDF rates were evaluated sequentially for non-digested percentage and data underwent analysis of variance (ANOVA p < 0.05; means were compared by tukey’s test (p < 0.05. Particle size and material employed for incubation affected iDM and iFDN at the initial periods of incubation (p < 0.05.

  9. Particle interactions in three-dimensional electrical field simulated by iterative dipole moment method

    Science.gov (United States)

    Liu, Le; Xie, Chuanchuan; Chen, Bo; Wu, Jiankang

    2016-06-01

    The dielectrophoresis (DEP) interactions of a few particles in a uniform two-dimensional (2D) electrical field have well been studied by Maxwell stress tensor (MST) method. Multiple particle interactions in three-dimensional (3D) electrical field are investigated in this work using iterative dipole moment (IDM) method which is an analytic algorithm without complicated numerical computations to solve for electrical field. The interactive DEP forces of particles calculated by IDM are found to be well agreed with those of MST method and much simple to implement. Using IDM method, a series of examples of multiple particles interactions and particle chains in a 3D uniform DC electrical field is presented. Randomly distributed similar dense particles (either all positive DEP (pDEP) or all negative DEP (nDEP) particles) in 3D uniform electrical field can generally form chains in lines parallel to the electrical field, except the case that all similar particles are in a plane perpendicular to the electrical field where the particles repel each other and move away in the plane. Randomly distributed dissimilar dense particles (mixture of pDEP and nDEP particles) can form (1) chains in lines, (2) clusters in a plane or (3) 3D groups. The chains, clusters and groups are of staggered arrangements of pDEP and nDEP particles, which are perpendicular to the electrical field.

  10. Exploring the Inert Doublet Model through the dijet plus missing transverse energy channel at the LHC

    CERN Document Server

    Poulose, P; Sridhar, K

    2016-01-01

    In this study of the Inert Doublet Model (IDM), we propose that the dijet + missing transverse energy channel at the Large Hadron Collider will be an effective way of searching for the scalar particles of the IDM. This channel receives contributions from gauge boson fusion, and $t-$channel production, along with contributions from $H^+$ associated production. We find that, for $\\sqrt{s} =13$ TeV with moderate luminosity, this channel has the potential to probe the IDM in the mass range of up to about 150 GeV, complementing other leptonic channel searches. We perform the analysis including study of the Standard Model (SM) background, and optimise the selection criteria employing suitable cuts on the kinematic variables to maximise the signal significance. In a scenario with light dark matter of mass about 65 GeV, charged Higgs in the intermediate mass range of around 150 GeV could be probed with a luminosity of about 500 fb$^{-1}$, whereas higher masses around 200 and 300 GeV require about 1 and 2 ab$^{-1}$ lu...

  11. Classical scale invariance in the inert doublet model

    CERN Document Server

    Plascencia, Alexis D

    2015-01-01

    The inert doublet model (IDM) is a minimal extension of the Standard Model (SM) that can account for the dark matter in the universe. Naturalness arguments motivate us to study whether the model can be embedded into a theory with dynamically generated scales. In this work we study a classically scale invariant version of the IDM with a minimal hidden sector, which has a $U(1)_{\\text{CW}}$ gauge symmetry and a complex scalar $\\Phi$. The mass scale is generated in the hidden sector via the Coleman-Weinberg (CW) mechanism and communicated to the two Higgs doublets via portal couplings. Since the CW scalar remains light, acquires a vacuum expectation value and mixes with the SM Higgs boson, the phenomenology of this construction can be modified with respect to the traditional IDM. We analyze the impact of adding this CW scalar and the $Z'$ gauge boson on the calculation of the dark matter relic density and on the spin-independent nucleon cross section for direct detection experiments. Finally, by studying the RG ...

  12. Isotope dilution mass spectrometry

    Science.gov (United States)

    Heumann, Klaus G.

    1992-09-01

    In the past isotope dilution mass spectrometry (IDMS) has usually been applied using the formation of positive thermal ions of metals. Especially in calibrating other analytical methods and for the certification of standard reference materials this type of IDMS became a routine method. Today, the progress in this field lies in the determination of ultra trace amounts of elements, e.g. of heavy metals in Antarctic ice and in aerosols in remote areas down to the sub-pg g-1 and sub-pg m-3 levels respectively, in the analysis of uranium and thorium at concentrations of a few pg g-1 in sputter targets for the production of micro- electronic devices or in the determination of sub-picogram amounts of230Th in corals for geochemical age determinations and of226Ra in rock samples. During the last few years negative thermal ionization IDMS has become a frequently used method. The determination of very small amounts of selenium and technetium as well as of other transition metals such as vanadium, chromium, molybdenum and tungsten are important examples in this field. Also the measurement of silicon in connection with a re-determination of Avogadro's number and osmium analyses for geological age determinations by the Re/Os method are of special interest. Inductively-coupled plasma mass spectrometry is increasingly being used for multi-element analyses by the isotope dilution technique. Determinations of heavy metals in samples of marine origin are representative examples for this type of multi-element analysis by IDMS. Gas chromatography-mass spectrometry systems have also been successfully applied after chelation of metals (for example Pt determination in clinical samples) or for the determination of volatile element species in the environment, e.g. dimethyl sulfide. However, IDMS--specially at low concentration levels in the environment--seems likely to be one of the most powerful analytical methods for speciation in the future. This has been shown, up to now, for species of

  13. 血管内皮生长因子在妊娠期糖尿病产妇所分娩新生儿脐血中的表达%Expression of vascular endothelial growth factor in serum of umbilical blood from the newborns of women with gestational diabetes mellitus

    Institute of Scientific and Technical Information of China (English)

    王萍; 张巍; 陈素娟

    2009-01-01

    Objective It is to study the expression and significance of vascular endothelial growth factor(VEGF) in serum of umbilical blood from the newborns of women with gestational diabetes mellitus(GDM). Methods Radioimmunoassay(RIA) was used to measure serum VEGF level of umbilical blood from 31 newborns of women with GDM(infants of diabetes mothers , IDM group) and 30 newborns of normal pregnancy women(control group). According to blood sugar, IDM group included 18 newborns with normal blood sugar(normal blood sugar group) and 13 newborns with hypoglycemia (hypoglycemia group). The level of blood sugar of 30 cases in control group was normal. Results The VEGF level of umbilical vein blood and umbilical artery blood in IDM group was significantly higher than that in control group (P<0.01). In control group, the VEGF level in umbilical artery blood was significantly higher than that in umbilical vein blood(P<0.05). VEGF level of umbilical artery blood in IDM hypoglycemia group was significantly higher than that in control group as well as in IDM normal blood sugar group(P<0.01 and P<0.05). Conclusion The serum VEGF level of umbilical vein and artery blood from the IDM was significantly higher than that of normal pregnancy women. The VEGF level of umbilical artery blood can reflect the severity degree of damage of GDM to their newborns.%目的 探讨血管内皮生长因子(VEGF)在妊娠期糖尿病(GDM)产妇分娩的新生儿(IDM)脐静脉、脐动脉血中的表达及其意义.方法 采用放射免疫分析法检测31例妊娠期糖尿病患者分娩的新生儿(IDM组)与30例健康产妇所分娩的新生儿(对照组)脐静脉、脐动脉血VEGF水平,IDM组新生儿按其出生后血糖水平分为IDM血糖正常组(18例)和IDM低血糖组(13例),对照组30例新生儿血糖均正常.结果 IDM组脐静脉血和脐动脉血VEGF水平均显著高于对照组(P均<0.01).对照组脐动脉血VEGF水平显著高于脐静脉血水平(P<0.05).IDM低血糖

  14. Chanting of the inner space: on symphonic and concertante works by Milorad Marinković

    Directory of Open Access Journals (Sweden)

    Janković-Beguš Jelena

    2015-01-01

    Full Text Available The opus of contemporary Serbian composer Milorad Marinković (b. 1976, which encompasses works of choral, chamber, concertante and symphony music, leans towards classical forms of artistic music, Serbian folklore music, and Serbian Orthodox church chant. This paper deals with pieces composed for larger instrumental ensembles: Herojska uvertira (Heroic Overture for symphony orchestra, Psalmodija (Psalmody for symphony orchestra, Koncert za klavir i orkestar (Piano concerto and Mala opera (Little Opera for chamber ensemble (septet with prominent soloist parts of flute and clarinet. Special attention is placed on different procedures used by Marinković to accomplish wholeness and integration of the musical tissue. This paper observes these pieces as examples of religious music, having in mind the composer’s own understanding of the notion. Among common characteristics of the observed works that justify this point of view are specific single movement forms and the prominent role of main thematic materials, a cyclic principle, and programmatic elements. References to Serbian church chant observed in Marinković’s instrumental works are also discussed, especially in parallel with the analogue procedures used by Ljubica Marić (1909- 2003, one of the composer’s role models. Although Marinković’s works for instrumental ensembles do not fall into the category of spiritual music in its narrow sense (as defined by the composer himself, in this paper they are nevertheless considered as “spiritual” in a broader sense, as an expression of the composer’s desire to spiritualize his entire artistic output.

  15. Toward a New, Musical Paradigm of Place: The Port River Symphonic of Chester Schultz

    Directory of Open Access Journals (Sweden)

    Robin, Ryan

    2014-05-01

    Full Text Available In privileging music as a focus for applied ecology, the goal of this essay is to deepen perspectives on the musical representation of land in an age of complex environmental challenge. As the metaphor driving public narration of environmental crises, the notion of Earth as our home—signified by the prefix “eco”—brings with it a critical expectation for the musical academy to retreat from bland talk about a “sense of place.” Based on the premise that damaged ecologies are a matter of concern to many people, Indigenous and Settler; and building on the late Val Plumwood’s theory of “shadow” or “denied” places (Australian Humanities Review 44, 2008, the author introduces Within Our Reach: A Symphony of the Port River Soundscapes by anti-elitist South Australian composer Chester Schultz (b. 1945. Inspired by the tradition of R. Murray Schafer’s performances for outdoor sites, Schultz predicated this niche symphony on the noise-polluting defoliation of Adelaide’s “wetland wonder,” the Old Port Reach. Presented as a series of narrative soundscapes, the symphony harnesses the power of music, including popular genres, to engender a sense of local “belonging” to the Port. In an ecological subtext an Indigenous Elder sings in the re-awakening language of the Kaurna people who, in 1890, were evicted from their “nourishing terrain” (terminology after Rose, 1996 by the CSR Sugar Refinery. Schultz’s ethical musical representation of local oral, natural and industrial history generates a benchmark opus for what shadow place composition might sound like in the modern global city.

  16. Vertebrate Reproduction.

    Science.gov (United States)

    Kornbluth, Sally; Fissore, Rafael

    2015-10-01

    Vertebrate reproduction requires a myriad of precisely orchestrated events-in particular, the maternal production of oocytes, the paternal production of sperm, successful fertilization, and initiation of early embryonic cell divisions. These processes are governed by a host of signaling pathways. Protein kinase and phosphatase signaling pathways involving Mos, CDK1, RSK, and PP2A regulate meiosis during maturation of the oocyte. Steroid signals-specifically testosterone-regulate spermatogenesis, as does signaling by G-protein-coupled hormone receptors. Finally, calcium signaling is essential for both sperm motility and fertilization. Altogether, this signaling symphony ensures the production of viable offspring, offering a chance of genetic immortality. PMID:26430215

  17. 8. ‘Wilful Melancholy’ or ‘a Vigorous and Manly Optimism’?: Rosa Newmarch and the Struggle against Decadence in the British Reception of Russian Music, 1897-1917

    OpenAIRE

    Bullock, Philip Ross

    2015-01-01

    In the late 19th century, Russian music came to enjoy a particularly prominent place in orchestral concerts in London, especially in the wake of Tchaikovsky’s visit to Cambridge and London in 1893. In particular, Tchaikovsky’s Sixth Symphony (the ‘Pathétique’) soon became one of the most regularly performed works of modern symphonic music. Colourful, passionate, seductively orchestrated and with an apparent sense of narrative and drama, it rapidly came to enjoy great popularity with the growi...

  18. Questionnaire investigation of musicians’ use of hearing protectors, self reported hearing disorders and their experience of their working environment

    DEFF Research Database (Denmark)

    Laitinen, Heli; Poulsen, Torben

    2008-01-01

    , and distortion, among other hearing disorders, which can affect their work more severely than a hearing loss. This study investigated the use of hearing protectors, the prevalence of self-reported hearing disorders among musicians, and the importance of these hearing disorders to the musicians. The...... musicians at three Danish symphony orchestras were asked to complete a questionnaire on the topic. Results showed that Danish musicians are aware of the dangers of loud music, yet they rarely use hearing protectors and not always correctly; however, musicians with hearing disorders use hearing protectors...

  19. The Third Way

    OpenAIRE

    Vasic, Nebojsa

    2013-01-01

    Seks-kanals videoinstallasjon, seks projeksjoner, seks skjermer, lyd. "The Third Way, 2007-2013, a six channel video installation. This city symphony-inspired work features phantom rides filmed in Belgrade, Ljubljana, Podgorica, Sarajevo, Skopje, and Zagreb along the cities’ Main Streets named in Tito’s honor, such as Marshal Tito’s Street, Tito’s Road, etc. The work is inspired by Dziga Vertov’s legendary film The Man with the Movie Camera, in which the director through montage blends a numb...

  20. Portfolio of compositions

    OpenAIRE

    Lam, Fung

    2012-01-01

    Title of Work 1) The Turing Test – a Studio Opera (60 mins). 2) Symphony for Chamber Orchestra (25 mins). 3) Treptow – for String Orchestra (10 mins). 4) Sonata for Alto Saxophone and Piano (12 mins). 5) Symphonic Overture from John Paul Jones (13 mins). 6) Hebridean Sunset Rag – for Violin and Piano (3 mins). 7 Treptow – for String Quartet (10 mins). 8) Ping for Solo Piano (after Samuel Beckett) 8 mins. 9) Orchestral Medley from John Paul Jones (9 mins). 10) Vo...

  1. Mozarts „Krönungskonzerte“ und sein Kompositionsstil in der Sicht des Münchner Hofklaviermeisters Joseph Grätz

    OpenAIRE

    Münster, Robert

    2001-01-01

    In his treatise Gründe zur Tonsetzkunst, the composer, teacher, and theorist Grätz reflected contemporaneous traditionalism in his opinions on the music of Mozart. While he stated that some of Mozart's piano concertos, including the C major, K.246, and the D major, K.538, exemplified the concerto as a passionate discourse between a solo player and an orchestra, Grätz also criticized the second 'Coronation' concerto (F major, K.459) as too complicated and resembling a symphony with an obligato...

  2. Letter from Jaffrey, New Hampshire: business is kabooming

    OpenAIRE

    Jane Harrigan

    2002-01-01

    Begin with a glittering silver chrysanthemum, 1,000 feet wide, exploding over the Washington Monument on the Fourth of July. Proceed to Boston, where, with each cymbal crash of the "American Symphony," the pistils of giant red flowers strobe 1,000 feet above the Charles River. Take your pick of 700 other fireworks displays from Miami to Minnesota to Montreal. If you could follow a string of colored stars from all these productions back to their source, the trail would end at a tan, brick, and...

  3. “Looking on darkness which the blind do see”: the Figure of the Blind Girl in Dickens and the Dickensian

    OpenAIRE

    Orestano, Francesca

    2016-01-01

    The article focuses on the theme of blindness in Dickens’s American Notes (1842) and in The Cricket on the Hearth (1845): sight impairment is treated as a vehicle to carry the reader from landscape to inscape, staging at once truth and deception, blindness and insight. Such dramatic irony is also the leitmotif of Wilkie Collins’s Poor Miss Finch (1872) and is fully acknowledged in André Gide’s La Symphonie pastorale (1919). Finally the cinema, notably Charlie Chaplin with City Lights (1932), ...

  4. Scholarship in Cyberspace : Music Research in the Digital Age

    Directory of Open Access Journals (Sweden)

    Rothfarb Lee

    2014-12-01

    Full Text Available Digital resources for humanistic research have expanded dramatically in the last two decades. Scholars can browse libraries and archives located around the world and read digitized documents on networked computers in the comfort of their university offices and private homes. This essay identifies and discusses several electronically accessible archives and bibliographic sources in the field of music theory, and goes on to briefly describe the usefulness of digitized resources in research on the reception of composer Anton Bruckner's symphonies and music theorist Heinrich Schenker's early education.

  5. VÀinö Raition Antigone op. 23 esimerkkinÀ suomalaisesta 1920-luvun musiikin modernismista

    OpenAIRE

    Isolammi, Hanna

    2007-01-01

    VÀinö Raitio (1891 1945) is a Finnish modernist composer whose 1920 s works consist mainly of tone poems for symphony orchestra. Raitio s early compositions were relatively well received by the critics and audience until the first public performance of his three-part orchestral work Antigone op. 23 (1921 1922). The highly negative reviews of Antigone caused Raitio to become considered as a composer of obscure and difficult style. In this thesis I analyze the thematics, form, orchestrat...

  6. BALTICA IV. Plant maintenance for managing life and performance

    Energy Technology Data Exchange (ETDEWEB)

    Hietanen, S.; Auerkari, P. [eds.] [VTT Manufacturing Technology, Espoo (Finland). Operational Reliability

    1998-12-31

    BALTICA IV International Conference on Plant Maintenance Managing Life and performance held on September 7-9, 1998 on board M/S Silja Symphony on its cruise between Helsinki-Stockholm and at Aavaranta in Kirkkonummi. The BALTICA IV conference provides a forum for the transfer of technology from applied research to practice. This is one of the two volumes of the proceedings of the BALTICA IV International Conference on Plant Maintenance Managing Life and Performance. The BALTICA IV conference focuses on new technology, recent experience and applications of condition and life management, and on improvements in maintenance strategies for safe and economical operation of power plants. (orig.)

  7. Strategic Thinking of the Internet of Things and M2M Services

    Institute of Scientific and Technical Information of China (English)

    Qi Qingzhong

    2010-01-01

    @@ Editor' s Desk: The Internet of Things is an important part of the emerging high-tech industry and has been recognized as one of the important technologies for addressing global financial crisis and revitalizing the economy. Therefore, at the beginning of the new year, we are honored to have invited Mr. Samuel Qi (Qi Qingzhong), a famous Chinese communication technology expert and GM of Shanghai Symphony Telecommunications Co., Ltd., to give his views on the development strategy of the Internet of Things and Machine to Machine (M2M) Communications.

  8. Development of isotope dilution-liquid chromatography/mass spectrometry combined with standard addition techniques for the accurate determination of tocopherols in infant formula

    International Nuclear Information System (INIS)

    Graphical abstract: -- Highlights: •ID-LC/MS method showed biased results for tocopherols analysis in infant formula. •H/D exchange of deuterated tocopherols in sample preparation was the source of bias. •Standard addition (SA)-ID-LC/MS was developed as an alternative to ID-LC/MS. •Details of calculation and uncertainty evaluation of the SA-IDMS were described. •SA-ID-LC/MS showed a higher-order metrological quality as a reference method. -- Abstract: During the development of isotope dilution-liquid chromatography/mass spectrometry (ID-LC/MS) for tocopherol analysis in infant formula, biased measurement results were observed when deuterium-labeled tocopherols were used as internal standards. It turned out that the biases came from intermolecular H/D exchange and intramolecular H/D scrambling of internal standards in sample preparation processes. Degrees of H/D exchange and scrambling showed considerable dependence on sample matrix. Standard addition-isotope dilution mass spectrometry (SA-IDMS) based on LC/MS was developed in this study to overcome the shortcomings of using deuterium-labeled internal standards while the inherent advantage of isotope dilution techniques is utilized for the accurate recovery correction in sample preparation processes. Details of experimental scheme, calculation equation, and uncertainty evaluation scheme are described in this article. The proposed SA-IDMS method was applied to several infant formula samples to test its validity. The method was proven to have a higher-order metrological quality with providing very accurate and precise measurement results

  9. CURRENT STATUS OF INDIVIDUAL DOSIMETRIC MONITORING IN UKRAINE.

    Science.gov (United States)

    Chumak, V; Deniachenko, N; Makarovska, O; Mihailescu, L-C; Prykhodko, A; Voloskyi, V; Vanhavere, F

    2016-09-01

    About 50 000 workers are being occupationally exposed to radiation in Ukraine. Individual dosimetric monitoring (IDM) is provided by 77 dosimetry services and laboratories of very different scale with a number of monitored workers ranging from several persons to ∼9000. In the present work, the current status of personal dosimetry in Ukraine was studied. The First National Intercomparison (FNI) of the IDM labs was accompanied by a survey of the laboratory operation in terms of coverage, types of dosimetry provided, instrumentation and methodologies used, metrological support, data recording, etc. Totally, 34 laboratories responded to the FNI call, and 18 services with 19 different personal dosimetry systems took part in the intercomparison exercise providing 24 dosimeters each for blind irradiation to photons of 6 different qualities (ISO N-series X-rays, S-Cs and S-Co sources) in a dose range of 5-60 mSv. Performance of the dosimetry labs was evaluated according to ISO 14146 criteria of matching trumpet curves with H0 = 0.2 mSv. The test revealed that 8 of the 19 systems meet ISO 14146 criteria in full, 5 other labs show marginal performance and 6 laboratories demonstrated catastrophic quality of dosimetric results. Altogether, 18 participating labs provide dosimetric monitoring to 37 477 workers (about three-fourths of all occupationally exposed workers), usually on monthly (nuclear industry) or quarterly (rest of applications) basis. Of this number, 20 664 persons (55 %) receive completely adequate individual monitoring, and the number of personnel receiving IDM of inadequate quality counts 3054 persons. PMID:26979804

  10. Direct μ-flow injection isotope dilution ICP-MS for the determination of heavy metals in oil samples

    International Nuclear Information System (INIS)

    The determination of trace elements in oil samples and their products is of high interest as their presence significantly affects refinery processes and the environment by possible impact of their combustion products. In this context, inductively coupled plasma mass spectrometry (ICP-MS) plays an important role due to its outstanding analytical properties in the quantification of trace elements. In this work, we present the accurate and precise determination of selected heavy metals in oil samples by making use of the combination of μ-flow direct injection and isotope dilution ICP-MS (ICP-IDMS). Spike solutions of 62Ni, 97Mo, 117Sn and 206Pb were prepared in an organic solvent, mixed directly with the diluted oil samples and tested to be fit for purpose for the intended ID approach. The analysis of real samples revealed strong matrix effects affecting the ICP-MS sensitivity, but not the isotope ratio measurements, so that accurate results are obtained by ICP-IDMS. Typical relative standard deviations were about 15% for peak area and peak height measurements, whereas the isotope ratios were not significantly affected (RSD < 2%). The developed method was validated by the analysis of a metallo-organic multi-element standard (SCP-21, typically applied as a calibration standard) and the standard reference material SRM1084a (wear metals in lubricating oil). The obtained results were in excellent agreement with the certified values (recoveries between 98% and 102%), so the proposed methodology of combining μ-flow direct injection and ICP-IDMS can be regarded as a new tool for the matrix-independent, multi-element and reliable determination of trace elements in oil and related organic liquids. (orig.)

  11. Isotope dilution mass spectrometry of microelectronically relevant heavy metal traces in high-purity cobalt

    International Nuclear Information System (INIS)

    Because cobalt and its silicides are increasingly used in microelectronic devices, an isotope dilution mass spectrometric (IDMS) method has been developed for trace analysis of relevant heavy metals (U, Th, Fe, Zn, Tl, and Cd) in high-purity cobalt. The measurements of the isotope ratios were carried out with a small thermal ionization quadrupole mass spectrometer by producing positive thermal ions in a single- or double-filament ion source. For the trace/matrix separation and the isolation of the different heavy metals, anion-exchange chromatography and an extraction method for iron were applied. The detection limits obtained were (in ng/g): U = 0.007, Th = 0.017, Tl = 0.06, Cd = 1, Zn = 8, and Fe = 11, which demonstrates that the particularly critical radioactive impurities uranium and thorium could be analysed down to the low pg/g range. Three cobalt samples of different purity were analysed with concentrations ranging from about 0.1 ng/g for U and Th in an ultra high-purity material produced for microelectronic purposes, up to about 70 μg/g for Cd in a cobalt sample with declared purity of 99.8%. Because IDMS usually results in accurate analytical results, it can be used in the future for calibration of other methods like glow discharge mass spectrometry, as could be shown by analysing one cobalt sample by both methods. IDMS can also be applied for the production of urgently needed certified standard reference materials in this important field of high technology. (orig.)

  12. A framework for implementation of user-centric identity management systems

    DEFF Research Database (Denmark)

    Adjei, Joseph K.; Olesen, Henning

    2010-01-01

    -ernments in many countries are implementing identity man-agement systems (IdMS) to curtail these incidences and to offer citizens the power to exercise informational self-determination. Using concepts from technology adoption and fit-viability theo-ries as well as the laws of identity, this paper analyzes the......Users increasingly become part of electronic transactions, which take place instantaneously without direct user involvement. This leads to the risk of data manipulation, identity theft and privacy violation, and it has become a major concern for individuals and businesses around the world. Gov...

  13. A universal SI-traceable isotope dilution mass spectrometry method for protein quantitation in a matrix by tandem mass tag technology.

    Science.gov (United States)

    Li, Jiale; Wu, Liqing; Jin, Youxun; Su, Ping; Yang, Bin; Yang, Yi

    2016-05-01

    Isotope dilution mass spectrometry (IDMS), an important metrological method, is widely used for absolute quantification of peptides and proteins. IDMS employs an isotope-labeled peptide or protein as an internal standard although the use of a protein provides improved accuracy. Generally, the isotope-labeled protein is obtained by stable isotope labeling by amino acids in cell culture (SILAC) technology. However, SILAC is expensive, laborious, and time-consuming. To overcome these drawbacks, a novel universal SI-traceable IDMS method for absolute quantification of proteins in a matrix is described with human transferrin (hTRF). The hTRF and a human serum sample were labeled with different tandem mass tags (TMTs). After mixing the TMT-labeled hTRF and serum sample together followed by digestion, the peptides were separated by nano-liquid chromatography and analyzed by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS). Using the signature peptides, we calculated the ratios of reporter ions from the TMT-labeled peptides which, in turn, allowed determination of the mass fraction of hTRF. The recovery ranged from 97% to 105% with a CV of 3.9%. The LOD and LOQ were 1.71 × 10(-5) g/g and 5.69 × 10(-5) g/g of hTRF in human serum, respectively, and the relative expanded uncertainty was 4.7% with a mass fraction of 2.08 mg/g. For comparison, an enzyme-linked immunosorbent assay (ELISA) method for hTRF yielded a mass fraction of 2.03 mg/g. This method provides a starting point for establishing IDMS technology to accurately determine the mass fractions of protein biomarkers in a matrix with traceability to SI units. This technology should support the development of a metrological method useful for quantification of a wide variety of proteins. PMID:26942737

  14. Development of a reference method for speciation analysis of methylmercury in fish by HPLC-ICPMS and species specific isotope dilution

    International Nuclear Information System (INIS)

    Full text: LNE, the French National Metrology Institute, has established from many years isotope dilution applied to ICPMS to be able to certify reference materials in the fields of environmental monitoring, health and food. The present work shows the method developed for the analysis of methylmercury in fish products. The process was realized with a HPLC coupled to an ICPMS after the extraction of mercury by the use of microwave heating. Double IDMS was involved for quantification. Sources of bias were estimated to be taken into account within the uncertainty budget realized with GUM recommendations. Fresh and lyophilized CRMs were analyzed for method validation. (author)

  15. Instruction Design Model for Self-Paced ICT System E-Learning in an Organization

    Directory of Open Access Journals (Sweden)

    Ridi Ferdiana

    2012-08-01

    Full Text Available Adopting an Information Communication and Technology (ICT system in an organization is somewhat challenging. User diversity, heavy workload, and different skill gap make the ICT adoption process slower. This research starts from a condition that a conventional ICT learning through short workshop and guidance book is not working well. This research proposes a model called ICT instruction design model (ICT-IDM. This model provides fast track learning through integration between multimedia learning and self-paced hands-on E-learning. Through this case study, we discovered that the proposed model provides 27% rapid learning adoption rather than conventional learning model.

  16. Secure bindings of SAML assertions to TLS sessions

    DEFF Research Database (Denmark)

    Kohlar, Florian; Schwenk, Jörg; Jensen, Meiko;

    2010-01-01

    strengthen the Same Origin Policy of the browser by taking into account the security guarantees TLS gives. In this paper, we present a third approach which is of further interest beyond IDM protocols: we bind the SAML assertion to the TLS session that has been agreed upon between client and the service......In recent research work, two approaches to protect SAML based Federated Identity Management (FIM) against man-in-the-middle attacks have been proposed. One approach is to bind the SAML assertion and the SAML artifact to the public key contained in a TLS client certificate. Another approach is to...

  17. Cosmic acceleration without dark energy

    International Nuclear Information System (INIS)

    In this work, we investigate the global dynamics of the universe within the framework of the Interacting Dark Matter (IDM) scenario. Considering that the dark matter obeys the collisional Boltzmann equation, we can obtain analytical solutions of the global density evolution, which can accommodate an accelerated expansion, equivalent to either the quintessence or the standard Λ models. This is possible if there is a disequilibrium between the DM particle creation and annihilation processes with the former process dominating, which creates an effective source term with negative pressure. We also find realistic solutions in which the present time is located after the inflection point.

  18. Certification of Pd and Pt single spikes and application to the quantification of Pt and Pd in automotive exhaust emissions

    Science.gov (United States)

    Vogl, Jochen; Meyer, Christian; Noordmann, Janine; Rienitz, Olaf; Geilert, Sonja

    2014-05-01

    Numerous epidemiological studies show the effect of increased ambient pollution. Therefore measurement networks for air quality have been installed worldwide and legislation requires the monitoring of air pollution. Besides monitoring it is also important to be able to identify, to quantify and finally to regulate the emission of distinct sources in order to improve the quality of life. Automotive vehicles are a major source of environmental pollution especially through contaminants such as CO, NOX, SOX and hydrocarbons which derive from petrol combustion, while for example Platinum Group Elements (PGE) can be present from catalytic converters. The release of PGE into the environment, however, may be damaging in terms of public health, ecological and economic interests. In order to reliably assess the risks from PGEs, traceable and thus comparable data on the release rates of PGE from automotive catalysers are needed. As no Certified Reference Materials (CRM) are available for such samples the development of analytical procedures enabling SI-traceable results will be challenging. Therefore reference procedures for Pd and Pt in automotive exhaust emissions based on isotope dilution mass spectrometry (IDMS) have been developed and applied to specifically sampled automotive exhaust emissions. Due to the commonly known advantages, IDMS often is applied for quantification PGEs, as is the case within this work. The main reasons here are the required accuracy and the low PGE mass fractions in the sample. In order to perform IDMS analysis the analyte element must be available in an isotopically enriched form as so-called spike material or solution thereof, which is mixed with the sample. Unfortunately, no certified PGE spike solutions are available yet. To fill this gap two single PGE spikes, one 106Pd and one 194Pt spike, have been produced and characterized. The selection of the isotopes, the production of the solutions and the ampoulation will be described in this

  19. Release of ammonia from HAN-type PHA

    International Nuclear Information System (INIS)

    A preliminary design basis for ammonia scrubbers in the DWPF has been issued. This design basis is based on a theoretical model of ammonia evolution from the SRAT, SME and RCT. It is desirable to acquire actual process data on ammonia evolution prior to performing detailed design of scrubbers for DWPF. The evolution of ammonia from the SRAT and SME in the Integrated DWPF Melter System (IDMS) was investigated during the HM4 run. In this run, Precipitate Hydrolysis Aqueous (PHA), which was made in the Precipitate Hydrolysis Experimental Facility (PHEF) using the HAN (hydroxylamine nitrate) process was used, thus resulting in PHA with a high concentration of ammonium ion

  20. Estimation of rare earth elements in dominant uranium, thorium, zirconium and titanium matrix by solvent extraction using a mixture of 2-ethyl hexyl dihydrogen phosphate and bis (2-ethylhexyl) phosphate in hydrochloric acid media

    International Nuclear Information System (INIS)

    The rare earth elements (REE) form a coherent group of elements having geological significance and strategic importance. They play an important role in geochemical processes. Their distribution is influenced by both magmatism and sedimentation. In industry they are used in electronics, super magnet, superconductors and in high tech. alloys. Various instrumental methods such as flame atomic absorption spectrometry (FAAS), X- ray fluorescence spectrometry (XRFS), Instrumental neutron activation analysis (INNA). Isotopic dilution mass spectrometry (IDMS), Inductively coupled plasma atomic emission spectrometry (ICP-AES) and Inductively coupled plasma mass spectrometry (ICPMS) are used for their determination

  1. Applying strategies from libertarian paternalism to decision making for prostate specific antigen (PSA screening

    Directory of Open Access Journals (Sweden)

    Black Amanda

    2011-04-01

    Full Text Available Abstract Background Despite the recent publication of results from two randomized clinical trials, prostate specific antigen (PSA screening for prostate cancer remains a controversial issue. There is lack of agreement across studies that PSA screening significantly reduces prostate cancer mortality. In spite of these facts, the widespread use of PSA testing in the United States leads to overdetection and overtreatment of clinically indolent prostate cancer, and its associated harms of incontinence and impotence. Discussion Given the inconclusive results from clinical trials and incongruent PSA screening guidelines, the decision to screen for prostate cancer with PSA testing is an uncertain one for patients and health care providers. Screening guidelines from some health organizations recommend an informed decision making (IDM or shared decision making (SDM approach for deciding on PSA screening. These approaches aim to empower patients to choose among the available options by making them active participants in the decision making process. By increasing involvement of patients in the clinical decision-making process, IDM/SDM places more of the responsibility for a complex decision on the patient. Research suggests, however, that patients are not well-informed of the harms and benefits associated with prostate cancer screening and are also subject to an assortment of biases, emotion, fears, and irrational thought that interferes with making an informed decision. In response, the IDM/SDM approaches can be augmented with strategies from the philosophy of libertarian paternalism (LP to improve decision making. LP uses the insights of behavioural economics to help people better make better choices. Some of the main strategies of LP applicable to PSA decision making are a default decision rule, framing of decision aids, and timing of the decision. In this paper, we propose that applying strategies from libertarian paternalism can help with PSA

  2. On-line double isotope dilution laser ablation inductively coupled plasma mass spectrometry for the quantitative analysis of solid materials

    International Nuclear Information System (INIS)

    Graphical abstract: Development and validation of a new on-line double IDMS methodology to achieve an accurate, precise, and time-effective strategy for direct determination of trace elements in solid samples by LA-ICP-MS. - Highlights: • Development of a double IDMS strategy for direct solid analysis by LA-ICP-MS. • The proposed method requires the sequential analysis of the sample and a standard. • The previous characterization of the spike solution is not required in double IDMS. • Quantitative bulk analysis of Sr, Rb and Pb were performed in silicate glasses and powdered samples. • Powdered samples were analyzed as pressed pellets and glasses prepared by fusion. - Abstract: We report on the determination of trace elements in solid samples by the combination of on-line double isotope dilution and laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS). The proposed method requires the sequential analysis of the sample and a certified natural abundance standard by on-line IDMS using the same isotopically-enriched spike solution. In this way, the mass fraction of the analyte in the sample can be directly referred to the certified standard so the previous characterization of the spike solution is not required. To validate the procedure, Sr, Rb and Pb were determined in certified reference materials with different matrices, including silicate glasses (SRM 610, 612 and 614) and powdered samples (PACS-2, SRM 2710a, SRM 1944, SRM 2702 and SRM 2780). The analysis of powdered samples was carried out both by the preparation of pressed pellets and by lithium borate fusion. Experimental results for the analysis of powdered samples were in agreement with the certified values for all materials. Relative standard deviations in the range of 6–21% for pressed pellets and 3–21% for fused solids were obtained from n = 3 independent measurements. Minimal sample preparation, data treatment and consumption of the isotopically-enriched isotopes are the

  3. Classification and Unification of the Microscopic Deterministic Traffic Models with Identical Drivers

    OpenAIRE

    Yang, Bo; Monterola, Christopher

    2015-01-01

    We show that all existing deterministic microscopic traffic models with identical drivers (including both two-phase and three-phase models) can be understood as special cases from a master model by expansion around well-defined ground states. This allows two traffic models to be compared in a well-defined way. The three-phase models are characterized by the vanishing of leading orders of expansion within a certain density range, and as an example the popular intelligent driver models (IDM) is...

  4. Estimativa da incerteza de medição em análise cromatográfica: abordagem sobre a quantificação de carbamato de etila em cachaça The measurement uncertainty estimation in chromatographic analisys: approach on the quantification of ethyl carbamate in " cachaça"

    Directory of Open Access Journals (Sweden)

    Marcus Henrique Campino de la Cruz

    2010-01-01

    Full Text Available The measurement uncertainty is useful to estimate the confidence of analytical results. Nowadays, a result without the uncertainty statement cannot be considered reliable, but the scientific literature still lacks examples of the estimate of the measurement uncertainty. This paper presents a practical and reliable description of the measurement uncertainty estimation of the analytical determination of ethyl carbamate in cachaça by GC-IDMS. The isotope dilution technique (ID associated with GC-MS was used to improve the accuracy. The uncertainty estimated corresponds to 10% of the mass fraction of ethyl carbamate (115 ± 11 ng/g, which is in agreement with ppb level.

  5. Improvement of analytical activities with DA and NDA measurements in the Tokai Reprocessing Plant

    International Nuclear Information System (INIS)

    Full text: The Tokai Reprocessing Plant (TRP) as the first pilot plant in Japan started a series of operational testing for spent fuel reprocessing of light water reactor in 1977. In the meantime with over 30 years, we have developed a lot of measurement techniques to establish a precise and effective accountability analysis as well as a safeguards analysis for use in the national and international verification on nuclear materials. Isotope Dilution Mass Spectrometry (IDMS) technique for accountability analysis of the uranium and plutonium in reprocessing solutions has been demonstrated for many years at the TRP. In the IDMS analysis for input solutions, isotope dilution spikes have been provided by IAEA and utilized in common mode since 1990. Experiences by the use of this method during more than 15 years have confirmed the performance data with uncertainty level of less than 0.1%. IDMS has been also applied to accountability samples of Pu nitrate solution and high active liquid waste etc. According to type of sample we have prepared kinds of isotope dilution spikes required in each measurement optimizing appropriate contents of U and Pu. It is therefore said that high performance measurement technique using IDMS is completely established in the field of nuclear reprocessing research. Its quality of the IDMS has been also proven by intercomparison analyses. In 1994 an updated K-edge densitometer (KED) for Pu product solution was installed in the laboratory for on-site verification measurement of inspection activity by national and international inspectors. Its development and installation were carried out as a part of Japan Support Program for Agency Safeguards (JASPAS). The KED system is installed in a glove box equipped with an X-ray generator, which is different type from previously system with X-ray sources using radioactive isotopes such as Co-57 and Se-75. In order to apply the improved KED system to safeguards measurements, one of the more difficult

  6. Subjective and Physiological Responses to Music Stimuli Controlled Over Activity and Preference.

    Science.gov (United States)

    Iwanaga; Moroki

    1999-01-01

    Results of physiological responses to music are inconclusive considering results of several studies, probably due to the insufficient control of the musical stimuli. The present study aimed to examine the effects of music type and preference on subjective and physiological responses using controlled stimuli by subjects' evaluations for music activity and preference. Subjects were 47 undergraduate students selected from a pool of 145 undergraduates. Results of evaluations of music activity and music preference for musical stimuli in preliminary research determined participation in the study. The music used in this study included the 4th movement of Tchaikovsky's Symphony No. 4 as an excitative piece and the 3rd movement of Mahler's Symphony No. 6 as a sedative one. The excitative music aroused feelings of vigor and tension more than did the sedative one, while sedative music eased tension. Favorite music, regardless of music type, lowered subjective tension. Physiological responses (heart rate, respiration, and blood pressure) were greater during excitative music than during sedative music. Music preference did not, however, affect physiological responses. These results indicate that the dominant factor affecting emotional response was music type but not preference. PMID:10519843

  7. Prevalence of orthorexia nervosa among Turkish performance artists.

    Science.gov (United States)

    Aksoydan, E; Camci, N

    2009-03-01

    The aim of the study was to determine the prevalence of orthorexia nervosa among the performance artists in the State Opera and Ballet and in the Bilkent University Symphony Orchestra. The study population consisted of 39 men and 55 women for a total of 94 artists with mean age of 33 years. The ORTO-15 test was used to determine the prevalence of orthorexia nervosa. Those subjects who scored below 40 in the ORTO-15 test were classified as having orthorexia nervosa. Mean score of the participants in the ORTO-15 test was 37.9+/-4.46. A total of 56.4% of the artists involved in the research scored below 40 in the ORTO-15 test. While the highest prevalence of orthorexia nervosa was recorded among opera singers (81.8%), it was 32.1% among ballet dancers and 36.4% among symphony orchestra musicians. The differences between the three groups were statistically significant. No difference was noted between mean ORTO-15 score by baseline characteristics as gender, age, educational level, work experience, body mass index, smoking and alcohol consumption. The research group have a higher socio-economic and education level than the majority of the general public in Turkey. Additionally, being an artist in Turkey means being a role model for the general public both in terms one's physical appearance and lifestyle. These may be the reason why artists are more sensitive to this issue. PMID:19367138

  8. Ambiguity as an Essential Aesthetic Principle in Musical Listening

    DEFF Research Database (Denmark)

    Bonde, Anders

    2006-01-01

    Stravinsky’s Symphonies of Wind Instruments represents a remarkable example of discontinuity. Here, a traditional sense of continuous development is troubled by a sequence of segments, which at first sight seems non-related. However, the noticeable discontinuous gestures appear only as a superfic...... immediate listening and a sense of coherence in the subsequent musical reflection.......’, ‘interlocking’, and ‘synthesis’ (Cone, 1962: 19f), to Jonathan Kramer’s accentuation of discontinuity as a ‘profound musical experience’ with the ‘proportional lengths of moments as the one remaining principle of formal coherence’ (Kramer, 1978: 182). Though, the general attempt to reveal the music’s ‘secret...... connections’ in the ‘disguise’ of discontinuity implies an either-or viewpoint, which tends to overlook the fact that the musical progression suggests mutually contradistinctive impressions and, as such, is essentially ambiguous. Thus, in this paper it is not my intention to assert that the Symphonies in...

  9. Altered but Not Silenced: How Shostakovich Retained His Voice as an Artist despite the Demands of a Dictator

    Directory of Open Access Journals (Sweden)

    Hope R. Strayer

    2013-12-01

    Full Text Available Can music that is regulated and restrained by a dictator still be inspired? This question reveals ideology concerning how music should be created and valued. Does outside control restrict artistic integrity and autonomy? Not all composers have been free to write whatever their soul demands. People in authority have held power and control over artistic processes. Dmitri Shostakovich was a Russian composer whose work was subjected to the tastes of a tyrannical ruler and Communist party. Though Shostakovich did not compose in an environment that fostered musical exploration, his work should not be mourned but celebrated. Shostakovich was not a victim, but a victor of his music by the way he composed in the midst of the threat of denouncement. Though Shostakovich wrote music to follow the demands of others, the music was still his by the very fact that he created it; he brought it into existence and highlighted it with nuances of his being and personality as he produced each work. This research examines three critical pieces of Shostakovich’s canon to ascertain whether controlled art subjected to the whims, preferences, and objectives of others can still be inspired. Though a composer might be told what to say, it is he who chooses how to word a phrase. Shostakovich’s output, particularly the first symphony, his opera Lady Macbeth of the Mtsensk District, and fifth symphony exemplify that restrained and restricted music does not necessitate a sacrifice in artistic integrity; it can be inspired, celebrated, and worthy of study.

  10. Finding partners to play the music of regulation.

    Science.gov (United States)

    Hardison, Ross C

    2016-03-31

    In this issue of Blood, Wilson et al generate and analyze a treasure trove of epigenetic data, such as transcription factor occupancy, histone modifications, and chromatin interaction frequencies, genome-wide (ie, epigenomic data), in a cell line model of hematopoietic stem/progenitor cells (HSPCs). To appreciate the importance of these data, consider an analogy of gene expression being a song or symphony (transcripts) played by musicians (transcription factors and transcriptional machinery) reading the score encoded in the genome sequence. Previous studies revealed the positions of a few transcription factors across the genome, so we only knew about, for example, the violinists and oboists. No wonder we did not understand how the music was being generated (how expression was regulated). By mapping the sites of occupancy of many more transcription factors (now a total of 29), as well as positions of 4 histone modifications and DNase hypersensitive sites, Wilson et al reveal many more of the players and their partners. Furthermore, their data on 3-dimensional interaction frequencies of chromatin show how groups of musicians (protein complexes) come together in an orchestra to read the score and perform a symphony. PMID:27034416

  11. In Situ Generation of ArCu from CuF2 Makes Coupling of Bulky Aryl Silanes Feasible and Highly Efficient.

    Science.gov (United States)

    delPozo, Juan; Casares, Juan A; Espinet, Pablo

    2016-03-14

    A bimetallic system of Pd/CuF2 , catalytic in Pd and stoichiometric in Cu, is very efficient and selective for the coupling of fairly hindered aryl silanes with aryl, anisyl, phenylaldehyde, p-cyanophenyl, p-nitrophenyl, or pyridyl iodides of conventional size. The reaction involves the activation of the silane by Cu(II) , followed by disproportionation and transmetalation from the Cu(I) (aryl) to Pd(II) , upon which coupling takes place. Cu(III) formed during disproportionation is reduced to Cu(I) (aryl) by excess aryl silane, so that the CuF2 system is fully converted into Cu(I) (aryl) and used in the coupling. Moreover, no extra source of fluoride is needed. Interesting size selectivity towards coupling is found in competitive reactions of hindered aryl silanes. Easily accessible [PdCl2 (IDM)(AsPh3 )] (IDM = 1,3-dimethylimidazol-2-ylidene) is by far the best catalyst, and the isolated products are essentially free from As or Pd (<1 ppm). The mechanistic aspects of the process have been experimentally examined and discussed. PMID:26895353

  12. Prostaglandin E2 plays a key role in the immunosuppressive properties of adipose and bone marrow tissue-derived mesenchymal stromal cells

    Energy Technology Data Exchange (ETDEWEB)

    Yanez, Rosa, E-mail: rosamaria.yanez@ciemat.es; Oviedo, Alberto, E-mail: alberto.oviedo@ciemat.es; Aldea, Montserrat, E-mail: montserrat.aldea@ciemat.es; Bueren, Juan A., E-mail: juan.bueren@ciemat.es; Lamana, Maria L., E-mail: maruja.lamana@ciemat.es

    2010-11-15

    Mesenchymal stromal cells (MSCs) have important immunosuppressive properties, but the mechanisms and soluble factors involved in these effects remain unclear. We have studied prostaglandin-E2 (PGE2) as a possible candidate implied in adipose tissue-derived MSCs (Ad-MSCs) immunosuppressive properties over dendritic cells and T lymphocytes, compared to bone marrow derived MSCs (BM-MSCs). We found that both MSCs inhibited the maturation of myeloid-DCs and plasmocytoid-DCs. High levels of PGE2 were detected in DCs/MSCs co-cultures. Its blockade with indomethacin (IDM) allowed plasmocytoid-DCs but not myeloid-DCs maturation. Additionally, high levels of PGE2 were found in co-cultures in which Ad-MSCs or BM-MSCs inhibited activated T cells proliferation and pro-inflammatory cytokines production. PGE2 blockade by IDM preserved T lymphocytes proliferation but did not restore the pro-inflammatory cytokines secretion. However, an increased expression of transcription factors and cytokines genes involved in the Th1/Th2 differentiation pathway was detected in the T cells co-cultured with Ad-MSCs, but not with BM-MSCs. In conclusion, we propose that PGE2 is a soluble factor mediating most of the immunosuppressive effects of Ad-MSCs and BM-MSCs over p-DCs maturation and activated T lymphocytes proliferation and cytokine secretion.

  13. Prostaglandin E2 plays a key role in the immunosuppressive properties of adipose and bone marrow tissue-derived mesenchymal stromal cells

    International Nuclear Information System (INIS)

    Mesenchymal stromal cells (MSCs) have important immunosuppressive properties, but the mechanisms and soluble factors involved in these effects remain unclear. We have studied prostaglandin-E2 (PGE2) as a possible candidate implied in adipose tissue-derived MSCs (Ad-MSCs) immunosuppressive properties over dendritic cells and T lymphocytes, compared to bone marrow derived MSCs (BM-MSCs). We found that both MSCs inhibited the maturation of myeloid-DCs and plasmocytoid-DCs. High levels of PGE2 were detected in DCs/MSCs co-cultures. Its blockade with indomethacin (IDM) allowed plasmocytoid-DCs but not myeloid-DCs maturation. Additionally, high levels of PGE2 were found in co-cultures in which Ad-MSCs or BM-MSCs inhibited activated T cells proliferation and pro-inflammatory cytokines production. PGE2 blockade by IDM preserved T lymphocytes proliferation but did not restore the pro-inflammatory cytokines secretion. However, an increased expression of transcription factors and cytokines genes involved in the Th1/Th2 differentiation pathway was detected in the T cells co-cultured with Ad-MSCs, but not with BM-MSCs. In conclusion, we propose that PGE2 is a soluble factor mediating most of the immunosuppressive effects of Ad-MSCs and BM-MSCs over p-DCs maturation and activated T lymphocytes proliferation and cytokine secretion.

  14. Exposure levels for persons involved in recovery operations following the Chernobyl accident in 1986-1987 and dosimetric data verification

    International Nuclear Information System (INIS)

    It is considered the organization of individual dosimetric monitoring (IDM) within 30-km zone around Chernobyl nuclear power plant (CNPP) in 1986 for different contingents of recovery workers: the CNPP personnel, Management for Construction 605 (MC-605), military recovery workers, persons assigned to 30-km zone. It is concluded that the quality of IDM had decreased in the following series: the MC-605 personnel, the CNPP personnel, the assigned persons, and military units. The method of dosimetric data verification for recovery workers in 1986 is presented. The results obtained by this method correspond to the results of the experts' estimation. Using the theory of hybrid lognormal distribution it was obtained, in our opinion, real external dose distribution for all the recovery workers. It was estimated that 7% of recovery workers received doses more than 0.25 Gy. Also, the data on values of mean and collective doses for different contingents, as well as for all persons involved in recovery operations is presented. 14 refs., 18 figs

  15. Multi-element trace determinations in pure alkaline earth fluoride powders by high-resolution ICP-MS using wet-chemical sample preparation and laser ablation

    Energy Technology Data Exchange (ETDEWEB)

    Tibi, Markus; Heumann, Klaus G. [Institute of Inorganic Chemistry and Analytical Chemistry, Johannes Gutenberg-University Mainz, Duesbergweg 10-14, 55099, Mainz (Germany)

    2003-09-01

    Four alternative analytical procedures for the determination of ten important trace impurities (Mg, Cr, Fe, Cu, Zn, Sr, Zr, Cd, Ba, and Pb) in pure alkaline earth fluoride powders were applied using high-resolution inductively coupled plasma mass spectrometry (ICP-MS). Two procedures are based on a wet-chemical microwave digestion with boric acid and quantification by the standard addition technique and isotope dilution mass spectrometry (IDMS), respectively. In addition, analyses are also performed by laser ablation as a direct solid sampling technique applying matrix-matched external calibration as well as isotope dilution of the powdered sample. For most elements good agreement between the different methods is found. Detection limits for laser ablation vary between 0.05 ng g{sup -1} for Zr and 20 ng g{sup -1} for Mg. They are about one to two orders of magnitude lower than those of the wet-chemical procedures, which is mainly due to the high dilution factor during the sample preparation step. Advantages and restrictions of the different analytical procedures are discussed with respect to their routine applicability. Due to its relatively high accuracy, low detection limits, and time-efficiency LA-ICP-IDMS is the preferred choice if no standard reference materials are available. (orig.)

  16. Determination of heavy metal complexes with humic substances by HPLC/ICP-MS coupling using on-line isotope dilution technique

    Energy Technology Data Exchange (ETDEWEB)

    Vogl, J.; Heumann, K.G. [Johannes Gutenberg-University Mainz, Institute of Inorganic Chemistry and Analytical Chemistry, Becherweg 24, D-55099 Mainz (Germany)

    1997-10-01

    An isotope dilution mass spectrometric (IDMS) method has been developed for the simultaneous determination of the complexes of 11 heavy metals (Ag, Cd, Cu, Mo, Ni, Pb, Tl, U, W, Zn and Zr) with humic substances (HS) by coupling HPLC with ICP-MS and applying the on-line isotope dilution technique. The HPLC separation was carried out with size exclusion chromatography. This HPLC/ICP-IDMS method was applied to samples from a brown water, ground water, sewage and seepage water as well as for a sample containing isolated fulvic acids. The total contents of heavy metals and of their complexes were analyzed in these samples with detection limits in the range of 5-110 ng/L. The analysis of heavy metal/HS complexes from the different waters resulted in characteristic fingerprints of the distribution pattern of heavy metals in the separated HS fractions. A comparison between the total heavy metal concentrations and their portions bound to humic substances showed distinct differences for the various metals. Simultaneous {sup 12}C detection was used for the characterization of HS complexes not identified by UV detection and for the determination of relative DOC concentrations of chromatographic peaks. (orig.) With 4 figs., 2 tabs., 10 refs.

  17. Investigation of mercury-containing proteins by enriched stable isotopic tracer and size-exclusion chromatography hyphenated to inductively coupled plasma-isotope dilution mass spectrometry

    International Nuclear Information System (INIS)

    In order to investigate trace mercury-containing proteins in maternal rat and their offspring, a method of enriched stable isotopic tracer (196Hg and 198Hg) combined with size-exclusion chromatography (SEC) coupled to inductively coupled plasma-isotope dilution mass spectrometry (ICP-IDMS) was developed. Prior to the analysis, 196Hg- and 198Hg-enriched methylmercury was administrated to the pregnant rats. Then the mercury-containing proteins in serum and brain cytosol of the dam and pup rats were separated by size-exclusion columns and the mercury was detected by ICP-MS. The ICP-MS spectrogram of the tracing samples showed significantly elevated 196Hg and 198Hg isotopic signals compared with the natural ones, indicating that the detection sensitivity could be increased by the tracer method. The contents of mercury in chromatographic fractions of the dam and pup rat brain cytosol were quantitatively estimated by post-column reverse ID-ICP-MS. The quantitative speciation differences of mercury in brain cytosol between the dam and pup rats were observed, indicating that such studies could be useful for toxicological estimation. Additionally, the isotopic ratio measurement of 198Hg/202Hg in the tracing samples could be used to identify the artifact mercury species caused in the analytical procedure. The study demonstrates that the tracer method combined with high-performance liquid chromatography (HPLC)-ICP-IDMS could provide reliably qualitative and quantitative information on mercury-containing proteins in organisms

  18. Development of a species-specific isotope dilution GC-ICP-MS method for the determination of thiophene derivates in petroleum products.

    Science.gov (United States)

    Heilmann, Jens; Heumann, Klaus G

    2008-01-01

    A species-specific isotope dilution technique for accurate determination of sulfur species in low- and high-boiling petroleum products was developed by coupling capillary gas chromatography with quadrupole ICP-MS (GC-ICP-IDMS). For the isotope dilution step 34S-labeled thiophene, dibenzothiophene, and mixed dibenzothiophene/4-methyldibenzothiophene spike compounds were synthesized on the milligram scale from elemental 34S-enriched sulfur. Thiophene was determined in gasoline, 'sulfur-free' gasoline, and naphtha. By analyzing reference material NIST SRM 2296, the accuracy of species-specific GC-ICP-IDMS was demonstrated by an excellent agreement with the certified value. The detection limit is always limited by the background noise of the isotope chromatograms and was determined for thiophene to be 7 pg absolute, which corresponds to 7 ng sulfur/g sample under the experimental conditions used. Dibenzothiophene and 4-methyldibenzothiophene were determined in different high-boiling petroleum products like gas oil, diesel fuel, and heating oil. In this case a large concentration range from about GC-ICP-MS and GC-EI-MS experiments (EI-MS electron impact ionization mass spectrometry) the substantial influence of co-eluting hydrocarbons on the ICP-MS sulfur signal was demonstrated, which can significantly affect results obtained by external calibration but not those by the isotope dilution technique. PMID:17874080

  19. Development of a species-specific isotope dilution GC-ICP-MS method for the determination of thiophene derivates in petroleum products

    Energy Technology Data Exchange (ETDEWEB)

    Heilmann, Jens; Heumann, Klaus G. [Johannes Gutenberg-University, Institute of Inorganic Chemistry and Analytical Chemistry, Mainz (Germany)

    2008-01-15

    A species-specific isotope dilution technique for accurate determination of sulfur species in low- and high-boiling petroleum products was developed by coupling capillary gas chromatography with quadrupole ICP-MS (GC-ICP-IDMS). For the isotope dilution step {sup 34}S-labeled thiophene, dibenzothiophene, and mixed dibenzothiophene/4-methyldibenzothiophene spike compounds were synthesized on the milligram scale from elemental {sup 34}S-enriched sulfur. Thiophene was determined in gasoline, 'sulfur-free' gasoline, and naphtha. By analyzing reference material NIST SRM 2296, the accuracy of species-specific GC-ICP-IDMS was demonstrated by an excellent agreement with the certified value. The detection limit is always limited by the background noise of the isotope chromatograms and was determined for thiophene to be 7 pg absolute, which corresponds to 7 ng sulfur/g sample under the experimental conditions used. Dibenzothiophene and 4-methyldibenzothiophene were determined in different high-boiling petroleum products like gas oil, diesel fuel, and heating oil. In this case a large concentration range from about < 0.04 to more than 2,000 {mu}g g{sup -1} was covered for both sulfur species. By parallel GC-ICP-MS and GC-EI-MS experiments (EI-MS electron impact ionization mass spectrometry) the substantial influence of co-eluting hydrocarbons on the ICP-MS sulfur signal was demonstrated, which can significantly affect results obtained by external calibration but not those by the isotope dilution technique. (orig.)

  20. Determination of Polychlorinated Biphenyls in Solid Samples by Isotope Dilution Mass Spectrometry Using ³⁷Cl-Labeled Analogues.

    Science.gov (United States)

    Somoano-Blanco, Lourdes; Rodriguez-Gonzalez, Pablo; García Fonseca, Sergio; Alonso, J Ignacio Garcia

    2015-08-01

    This work describes the first application of (37)Cl-labeled compounds to isotope dilution mass spectrometry (IDMS). The synthesis of 12 (37)Cl-labeled polychlorinated biphenyls (PCBs) was carried out by the chlorination of biphenyl with isotopically enriched chlorine gas, generated by the direct oxidation of Na(37)Cl with potassium peroxymonosulfate. After an exhaustive purification due to the presence of other congeners, the concentration and the isotopic enrichment of all (37)Cl-labeled PCBs in the mixture was determined. The proposed procedure allows the simultaneous quantification of every isotope diluted PCB congener in a single gas chromatography-tandem mass spectrometry (GC-MS/MS) injection without resorting to a methodological calibration graph. The results obtained here demonstrate that the use of (37)Cl-labeled analogues provides results in agreement with the certified values of three different Certified Reference Materials (marine sediment SRM 1944, fish tissue 1947, and loamy soil CRM 962-50) and analytical figures of merit comparable to those obtained using regular IDMS procedures based on the use of commercially available (13)C-labeled analogues. PMID:26165349

  1. Performance of a HPGe System for Surface and Container Measurements - 13582

    International Nuclear Information System (INIS)

    The decommissioning of a nuclear facility or post-accident cleanup is an immense engineering effort requiring an array of specialist tools and techniques. The decommissioning and cleanup activities generate large quantities of low activity waste. For economic disposal, it is desirable to certify the waste as suitable for free release. Every container must be assayed to a sufficient degree of accuracy and sensitivity so that it may be certified to be or not to be suitable for 'free release'. In a previous work, the performance of a highly-automated system for free release of large numbers of containers was presented in which the spectroscopy hardware comprised four ORTEC Interchangeable Detector Module (IDM) mechanically cooled HPGe spectrometers in conjunction with ORTEC ISOPlus waste assay software. It was shown that the system was capable of assaying large containers to free release levels in reasonable measurement times. Not all operations have enough waste to justify an automated system or rapid assay results may be required, perhaps in a remote location. To meet this need, a new mobile system has been developed for the assay of smaller objects (drums, boxes, and surfaces) In-Situ. The system incorporates the latest generation IDM-200 and ISOPlus software and a new variant of the ISOCart hardware. This paper will describe the system and performance. (authors)

  2. A mediator embedded micro-immunosensing unit for electrochemical detection on viruses within physiological saline media

    International Nuclear Information System (INIS)

    To provide a time- and cost-saving alternative to the conventional methods for virus detection in biological media, this work presents an electrochemical micro-immunosensor based on the nickel hexacyanoferrate (NiHCF) redox mediator film coating the interdigitated microelectrodes (IDMEs). By chelation binding with no additional cross-linker, the 6xHis-tagged antibodies were immobilized on a NiHCF film. Secondly, an immunoassay response was enhanced by employing microbeads coated with 6xHis antibody. The electrochemical properties and the stability of the NiHCF film modified IDMEs were evaluated by cyclic voltammetry. The bead-induced impedance variations at the electrode film/electrolyte interface were characterized by electrochemical impedance spectroscopy and verified using FEM simulation. Experiments of virus detection were conducted through targeting the antigens of the vital infectious salmon viruses, such as infectious salmon anaemia virus, infectious pancreatic necrosis virus and salmonid alphavirus subtype 3. The micro-immunosensor exhibited detection limits as low as 10 pg ml−1 and detection sensitivities as high as 57.5 kΩ µM−1 within a physiological saline solution. Tests for multiple antigen–antibody interactions showed good detection specificity, as confirmed by ELISA. By incorporating the microfluidic network, electrochemical impedance micro-immunosensing units can be realized in a fully integrated platform for multiplex virus detection in tissue samples.

  3. Low Energy Gamma Ray Excess Confronting a Singlet Scalar Extended Inert Doublet Dark Matter Model

    CERN Document Server

    Banik, Amit Dutta

    2014-01-01

    Recent study of gamma rays originating from the region of galactic centre has confirmed an anomalous $\\gamma$-ray excess within the energy range 1-3 GeV. This can be explained as the consequence of pair annihilation of a 31-40 GeV dark matter into $b \\bar b$ with thermal annihilation cross-section $\\sigma v \\sim 1.4-2.0 \\times 10^{-26}~\\rm{cm^3/s}$. In this work we revisit the Inert Doublet Model (IDM) in order to explain this gamma ray excess. Taking the lightest inert particle (LIP) as a stable DM candidate we show that a 31-40 GeV dark matter derived from IDM will fail to satisfy experimental limits on dark matter direct detection cross-section obtained from ongoing direct detection experiments and is also inconsistent with LHC findings. We show that a singlet extended inert doublet model can easily explain the reported $\\gamma$-ray excess which is as well in agreement with Higgs search results at LHC and other observed results like DM relic density and direct detection constraints.

  4. An intercomparison experiment on isotope dilution thermal ionisation mass spectrometry using plutonium-239 spike for the determination of plutonium concentration in dissolver solution of irradiated fuel

    International Nuclear Information System (INIS)

    Determination of plutonium concentration in the dissolver solution of irradiated fuel is one of the key measurements in the nuclear fuel cycle. This report presents the results of an intercomparison experiment performed between Fuel Chemistry Division (FCD) at BARC and PREFRE, Tarapur for determining plutonium concentration in dissolver solution of irradiated fuel using 239Pu spike in isotope dilution thermal ionisation mass spectrometry (ID-TIMS). The 239Pu spike method was previously established at FCD as viable alternative to the imported enriched 242Pu or 244Pu; the spike used internationally for plutonium concentration determination by IDMS in dissolver solution of irradiated fuel. Precision and accuracy achievable for determining plutonium concentration are compared under the laboratory and the plant conditions using 239Pu spike in IDMS. For this purpose, two different dissolver solutions with 240Pu/239Pu atom ratios of about 0.3 and 0.07 corresponding, respectively, to high and low burn-up fuels, were used. The results of the intercomparison experiment demonstrate that there is no difference in the precision values obtained under the laboratory and the plant conditions; with mean precision values of better than 0.2%. Further, the plutonium concentration values determined by the two laboratories agreed within 0.3%. This exercise, therefore, demonstrates that ID-TIMS method using 239Pu spike can be used for determining plutonium concentration in dissolver solution of irradiated fuel, under the plant conditions. 7 refs., 8 tabs

  5. Modeling Method for Increased Precision and Scope of Directly Measurable Fluxes at a Genome-Scale.

    Science.gov (United States)

    McCloskey, Douglas; Young, Jamey D; Xu, Sibei; Palsson, Bernhard O; Feist, Adam M

    2016-04-01

    Metabolic flux analysis (MFA) is considered to be the gold standard for determining the intracellular flux distribution of biological systems. The majority of work using MFA has been limited to core models of metabolism due to challenges in implementing genome-scale MFA and the undesirable trade-off between increased scope and decreased precision in flux estimations. This work presents a tunable workflow for expanding the scope of MFA to the genome-scale without trade-offs in flux precision. The genome-scale MFA model presented here, iDM2014, accounts for 537 net reactions, which includes the core pathways of traditional MFA models and also covers the additional pathways of purine, pyrimidine, isoprenoid, methionine, riboflavin, coenzyme A, and folate, as well as other biosynthetic pathways. When evaluating the iDM2014 using a set of measured intracellular intermediate and cofactor mass isotopomer distributions (MIDs),1 it was found that a total of 232 net fluxes of central and peripheral metabolism could be resolved in the E. coli network. The increase in scope was shown to cover the full biosynthetic route to an expanded set of bioproduction pathways, which should facilitate applications such as the design of more complex bioprocessing strains and aid in identifying new antimicrobials. Importantly, it was found that there was no loss in precision of core fluxes when compared to a traditional core model, and additionally there was an overall increase in precision when considering all observable reactions. PMID:26981784

  6. A physiological delay in human fetal hemoglobin switching is associated with specific globin DNA hypomethylation.

    Science.gov (United States)

    Perrine, S P; Greene, M F; Cohen, R A; Faller, D V

    1988-02-01

    The human fetal-to-adult globin switch normally occurs on a fixed schedule, beginning at 32-34 weeks gestation, and recent studies have suggested an association between this developmental inactivation of the fetal (gamma) globin genes and the appearance of methylation within and around these genes. We have studied a population of infants in whom this switch does not occur before birth (infants of diabetic mothers, IDM) and examined the patterns of methylation surrounding their active gamma-globin genes, in comparison to the gamma-globin genes of age-matched controls who have switched their pattern of globin gene expression on schedule. All genomic DNA samples from infants with delays in the globin switch demonstrated extensive hypomethylation in the region of the gamma-globin genes, comparable to that found in the genomes of fetuses of less than 21 weeks gestation. DNA from the erythroid cells of infants of 32-40 weeks gestation had no detectable hypomethylation in the gamma-globin region. These findings support the concept that hypomethylation is an accurate developmental marker of globin gene switching, and suggest that globin gene expression in IDM may be arrested at an early preswitch stage. PMID:2449361

  7. The second generation intelligent user interface for the crustal dynamics data information system. [for nasa space missions

    Science.gov (United States)

    Short, Nicholas, Jr.; Wattawa, Scott L.

    1988-01-01

    For the past decade, operations and research projects that support a major portion of NASA's overall mission have experienced a dramatic increase in the volume of generated data and resultant information that is unparalleled in the history of the agency. The effect of such an increase is that most of the science and engineering disciplines are undergoing an information glut, which has occurred, not only because of the amount, but also because of the type of data being collected. This information glut is growing exponentially and is expected to grow for the foreseeable future. Consequently, it is becoming physically and intellectually impossible to identify, access, modify, and analyze the most suitable information. Thus, the dilemma arises that the amount and complexity of information has exceeded and will continue to exceed, using present information systems, the ability of all the scientists and engineers to understand and take advantage of this information. As a result of this information problem, NASA has initiated the Intelligent Data Management (IDM) project to design and develop Advanced Information Management (IDM) project to design and develop Advanced Information Management Systems (AIMS). The first effort of the Project was the prototyping of an Intelligent User Interface (IUI) to an operational scientific database using expert systems, natural language processing, and graphics technologies. An overview of the IUI formulation and development for the second phase is presented.

  8. Interaction Dynamics in AEC Global Teamwork

    Institute of Scientific and Technical Information of China (English)

    Renate Fruchter; Shubashri Swaminathan; Naohiro Matsumura; Yukio Ohsawa

    2008-01-01

    Architecture,engineering,and construction (AEC) global project teamwork is communication in-tensive and relies heavily on synchronous and asynchronous information and collaboration technologies (ICT).We explore in this paper how an asynchronous ICT,called ThinkTank,reshaped the work practice of design-construction global teams.and how the interaction with this ICT reshaped the purpose and benefits of its use.ThinkTank is a web-based asynchronous collaboration and discussion forum.We introduce the influence diffusion model (IDM) that formalizes the process of identifying the influence of people,messages,and terms mathematically.Discovering who the influence leaders in project teams are can be beneficial and critical from a corporate management perspective.since they can guide or motivate the team towards suc-cessful actions and outcomes.We present the ThinkTank-IDM integrated system and its validation with a testbed of 53 AEC global team project archived in ThinkTank over 8 years.

  9. Trueness investigation of routine creatinine assays on nine homogeneous systems in Beijing demonstrates an encouraging outcome that meets clinical requirements

    Institute of Scientific and Technical Information of China (English)

    LIU Yan; XU Guo-bin

    2010-01-01

    Background Serum creatinine (Scr) measurement plays a key role in glomerular filtration rate estimation (eGFR),chronic kidney disease (CKD) diagnosis as well as CKD treatment. However, the test results of Scr from different laboratories vary significantly. In order to get comparable results, the European in vitro diagnostic (IVD) directive requires traceability to reference methods and materials. The purpose of this study was to verify the effect of traceability implementation by investigating the trueness of creatinine measurement on nine homogenous systems in Beijing. Methods Commutable frozen human serum reference material, National Institute of Standards & Technology (NIST) Standard Reference Material (SRM) 967, was used to verify the trueness of Scr measurement results from nine homogeneous analytical systems of seven companies which are the most widely used systems in Beijing's third-grade hospitals. The methods referred to the Jaffe's and Enzymatic methods. Results from nine routine measurement systems were assessed using two criteria: biological variability and Clinical Laboratory Improvement Amendments' 88 (CLIA' 88).We simulated a series of broken lines representing the limits of SD and bias that would produce a relative increase (or decrease) of 10% and 20% in the measurement error when estimating GFR (MEeGFR) using the isotope dilution mass spectrometry (IDMS)-traceable Modification of Diet in Renal Disease (MDRD) Study equation. Results of the College of American Pathologists (CAP) 2008-B LN24 Survey were compared with our investigation results. Results Compared with the total error criteria of biological variability, Ortho (traceable to IDMS) met the minimum acceptable criteria; Roche (Jaffe), Roche (Enzymatic), Shino and Daiichi met the desirable criteria at level Ⅰ. At level Ⅱ, Ortho (traceable to gas chromatography/isotope dilution mass spectrometry, GC/IDMS), Dade Behring and Beckman (traceable to rate Jaffe) met the minimum acceptable

  10. Alterações pulmonares em um modelo de diabetes mellitus em ratos: o efeito da terapia antioxidante Lung alterations in a rat model of diabetes mellitus: effects of antioxidant therapy

    Directory of Open Access Journals (Sweden)

    Luiz Alberto Forgiarini Junior

    2010-10-01

    -only (without DM but treated with SOD; IDM-only (with streptozotocininduced DM but untreated; and IDM+SOD (with streptozotocin-induced DM, treated with SOD. The animals were evaluated over a 60-day period, day 0 being defined as the day on which the streptozotocin-injected animals presented glycemia > 250 mg/dL. The SOD was administered for the last 7 days of that period. At the end of the study period, samples of lung tissue were collected for histopathological analysis, evaluation of tissue oxidative stress, and assessment of DNA damage. RESULTS: There were no significant differences among the groups regarding DNA damage. In the IDM-only group, there was a significant increase in the extracellular matrix and significantly greater hyperplasia of the capillary endothelium than in the SOD-only and control groups. In addition, there were significant changes in type II pneumocytes and macrophages, suggesting an inflammatory process, in the IDM-only group. However, in the IDM+SOD group, there was a reduction in the extracellular matrix, as well as normalization of the capillary endothelium and of the type II pneumocytes. CONCLUSIONS: Exogenous SOD can reverse changes in the lungs of animals with induced DM.

  11. Bamboo and Wood in Musical Instruments

    Science.gov (United States)

    Wegst, Ulrike G. K.

    2008-08-01

    Over centuries and millennia, our ancestors worldwide found the most appropriate materials for increasingly complex acoustical applications. In the temperate climate of Europe, where the instruments of the Western symphony orchestra were developed and perfected, instrument makers still primarily take advantage of the unique property combination and the aesthetic appeal of wood. In all other continents, one material dominates and is frequently chosen for the manufacture of wind, string, and percussion instruments: the grass bamboo. Here, we review from a materials science perspective bamboo's and wood's unique and highly optimized structure and properties. Using material property charts plotting acoustic properties such as the speed of sound, the characteristic impedance, the sound radiation coefficient, and the loss coefficient against one another, we analyze and explain why bamboo and specific wood species are ideally suited for the manufacture of xylophone bars and chimes, flutes and organs, violins and zithers, violin bows, and even strings.

  12. Sweet Melodies: Combining the Talents and Knowledge of Music Therapy and Elite Musicianship

    Directory of Open Access Journals (Sweden)

    Helen Shoemark

    2009-07-01

    Full Text Available This article reports on a collaborative short-term project between the Melbourne Symphony Orchestra and the Music Therapy team at The Royal Children's Hospital, Melbourne to provide live music on the Neonatal ward of the hospital. The focus was for the music therapists and musicians to develop their understanding and capability to provide live music in an environment for medically fragile patients. To extend the benefit of this experience, guidelines for future musicians were also produced. The guidelines were created through a process of narratives and discussions which were transcribed, and subjected to a thematic analysis. Mid and final review meetings for the whole team encouraged discussion about the emerging themes and final collation of guidelines. The guidelines were intended to offer guidance for new Arts in Health programs or for solo musicians volunteering in a hospital without such a program.

  13. MR-guided laser-induced thermotherapy with a cooled power laser system: a case report of a patient with a recurrent carcinoid metastasis in the breast

    Energy Technology Data Exchange (ETDEWEB)

    Vogl, Thomas J.; Mack, Martin G.; Straub, Ralf; Eichler, Katrin; Zangos, Stephan; Engelmann, Kerstin; Hochmuth, Kathrin; Ballenberger, Sabine; Jacobi, Volkmar; Diebold, Thomas [Institute of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Johann Wolfgang Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt/Main (Germany)

    2002-07-01

    We report a case of a 52-year-old woman with a palpable recurrent metastasis of a neuroendocrine carcinoma to the upper outer quadrant of the right breast. For the treatment of this lesion, MR-guided laser-induced thermotherapy was performed with a cooled power laser system (Nd:YAG-Laser). An open 0.2-T MR unit was used for the monitoring of the laser energy delivery to the breast; thus, a thermosensitive fast low-angle shot 2D sequence for MR thermometry was used, so the ablation of the tumor and the increase of laser-induced necrosis could be interactively visualized with the repetitive use of this sequence. The postinterventional MR control exams 1 day and 4 months after laser-induced thermotherapy at the 1.5-T MR unit (Magnetom Symphony Quantum, Siemens, Erlangen, Germany) verified the complete ablation of the tumor without any signs of residual or relapsing tumor. (orig.)

  14. Recent multi-purpose hall designs in Denmark with physically variable acoustics

    DEFF Research Database (Denmark)

    Gade, Anders Christian

    1999-01-01

    This paper describes two recent Danish multi-purpose hall designs, in which acoustic variability has been accomplished in different ways: through variable absorption and variable volume, respectively. The different approaches were chosen in order to insure that not only reverberation time (T......) and so clarity (C), but also the strength parameter (G) could be varied in a favorable direction in view of the prescribed uses of the halls. The hall with variable absorption is the assembly hall in the new extension to the Royal Library in Copenhagen to open in fall 1999. This hall will seat 600 people...... and be used for chamber music concerts, symphony orchestra rehearsals, and amplified speech. For the latter two functions, a reduction in G along with reduction in T was considered favorable. The hall with variable volume is the recently opened Esbjerg Musikhus seating 1100 and equipped with a full stage...

  15. The Myth of the IMF

    Science.gov (United States)

    Melnick, J.

    2009-11-01

    The Myth of Science is the idea that complex phenomena in Nature can be reduced to a set of equations based on the fundamental laws of physics. The Myth of the IMF is the notion that the observed distribution of stellar masses at birth (the IMF) can and must be explained by any successful theory of star formation. In this contribution I argue that the IMF is the result of the complex evolution of the interstellar medium in galaxies, and that as such the IMF preserves very little information, if any, about the detailed physics of star formation. Trying to infer the physics of star formation from the IMF is like trying to understand the personality of Beethoven from the power-spectrum of the Ninth Symphony!

  16. THE MYTH OF THE IMF

    Directory of Open Access Journals (Sweden)

    J. Melnick

    2009-01-01

    Full Text Available The Myth of Science is the idea that complex phenomena in Nature can be reduced to a set of equations based on the fundamental laws of physics. The Myth of the IMF is the notion that the observed distribution of stellar masses at birth (the IMF can and must be explained by any successful theory of star formation. In this contribution I argue that the IMF is the result of the complex evolution of the interstellar medium in galaxies, and that as such the IMF preserves very little information, if any, about the detailed physics of star formation. Trying to infer the physics of star formation from the IMF is like trying to understand the personality of Beethoven from the power-spectrum of the Ninth Symphony!

  17. From modernism to socialist realism in four years: Myaskovsky and Asafyev

    Directory of Open Access Journals (Sweden)

    Frolova-Walker Marina

    2003-01-01

    Full Text Available Two outstanding personalities of the Soviet musical life in the 1920's, the composer Nikolay Myaskovsky and the musicologist Boris Asafyev, both exponents of modernism, made volte-faces towards traditionalism at the beginning of the next decade. Myaskovsky's Symphony no. 12 (1931 and Asafyev's ballet The Flames of Paris (1932 became models for Socialist Realism in music. The letters exchanged between the two men testify to the formers uneasiness at the great success of those of his works he considered not valuable enough, whereas the latter was quite satisfied with his new career as composer. The examples of Myaskovsky and Asafyev show that early Soviet modernists made their move away from avant-garde creativity well before they faced any real danger from the bureaucracy.

  18. [The final year of Gustav Mahler].

    Science.gov (United States)

    von der Lippe, A

    1993-12-10

    "I am three times without a country; a Bohemian among Austrians, an Austrian among Germans, and a Jew among all the peoples of the world". This famous quotation is typical of Gustav Mahler (1860-1911) and reflects his difficult and stormy life. His rheumatic mitral valve disease, diagnosed in 1907, was probably asymptomatic until recurrent throat infections put an end to his life. At the time of his death Mahler was at the peak of his career as a conductor, with 90 concerts scheduled for the 1910-11 season. He had completed his 9th and begun his 10th symphony, but would his real task as a composer have survived the serious domestic crisis and threatened his artistic life? "My time will come" said Mahler, and by this he meant the acknowledgement of his music. But this took a long time. Today Mahler's music is played all over the world. Without doubt he is "eternal among the great". PMID:8278964

  19. Interstitial cells of Cajal, the Maestro in health and disease

    Directory of Open Access Journals (Sweden)

    Randa M Mostafa, Yasser M Moustafa, Hosam Hamdy

    2010-07-01

    Full Text Available Interstitial cells of Cajal (ICC are important players in the symphony of gut motility. They have a very significant physiological role orchestrating the normal peristaltic activity of the digestive system. They are the pacemaker cells in gastrointestinal (GI muscles. Absence, reduction in number or altered integrity of the ICC network may have a dramatic effect on GI system motility. More understanding of ICC physiology will foster advances in physiology of gut motility which will help in a future breakthrough in the pharmacological interventions to restore normal motor function of GI tract. This mini review describes what is known about the physiologic function and role of ICCs in GI system motility and in a variety of GI system motility disorders.

  20. Sing to Jahweh!... Cursed be the day on which I was born! A paradoxical harmony in Jeremiah 20:7-18

    Directory of Open Access Journals (Sweden)

    L. C. Bezuidenhout

    1990-01-01

    Full Text Available The paradoxical juxtaposition of the statements ‘Sing to Jahweh!... Cursed be the day on which I was born!’ in Jeremiah 20:13 and 20:14 creates a tension which can be avoided if these two verses are isolated from each other by way of redaction criticism. In this article, the possibility and even appropriateness of respecting the relationship between these verses is explored. The segment 7-12 is regarded as a double lament. The segments 13 and 14-18 constitute two contrasting conclusions. This segmentation coincides with time-honoured divisions of the text. Verses 7-18 can be defined as an integral unit where an ironic symphony is created by a central metaphor of procreation and counterpointed radial metaphors of sexual abuse and childbirth.

  1. Millikan Lecture 2009: Physics for all: From special needs to Olympiads

    Science.gov (United States)

    Eisenkraft, Arthur

    2010-04-01

    Can "all" students learn "real" physics? Physics First and Physics for All have become a success story for thousands of students in urban, suburban, and rural districts. At the same time, the International Physics Olympiad and other competitions have raised the expectation of what the most motivated students can achieve. Many physics educators are exploring ways to set higher goals for our most gifted students while also providing physics instruction to students previously excluded from our physics classes. Great novels and symphonies are accessible to people of different backgrounds and levels of expertise. We should develop teaching strategies that enable us to share an understanding of physics with all students because everyone deserves an opportunity to reflect on the wondrous workings of our universe.

  2. War and Peace: 200 Years of Australian-German Artistic Relations

    Directory of Open Access Journals (Sweden)

    Butler, Rex

    2015-04-01

    Full Text Available An overview of Australian-German Artistic Relations over the past two hundred years. The guns were barely silent on the Western Front when on 23 November 1918 Belgian-born Henri Verbrugghen took to the stage of the recently established NSW Conservatorium and softly tapped his baton, bringing the audience to silence. Then into this silence Verbrugghen called down the immortal opening chords of Beethoven’s Ninth Symphony, the ‘Choral’, with its celebrated fourth movement ‘Ode to Joy’, based on Schiller’s words. A difficult piece to stage because of the considerable orchestral forces required, the performance was nevertheless a triumph, and all the more so for the occasion it marked, the Allied victory over Germany. Due to the long lead time and the necessity for extensive rehearsal, its being played at the signing of peace was a coincidence, but nevertheless a very serendipitous one.

  3. Optimization of Orchestral Layouts Based on Instrument Directivity Patterns

    Science.gov (United States)

    Stroud, Nathan Paul

    The experience of hearing an exceptional symphony orchestra perform in an excel- lent concert hall can be profound and moving, causing a level of excitement not often reached for listeners. Romantic period style orchestral music, recognized for validating the use of intense emotion for aesthetic pleasure, was the last significant development in the history of the orchestra. In an age where orchestral popularity is waning, the possibil- ity of evolving the orchestral sound in our modern era exists through the combination of our current understanding of instrument directivity patterns and their interaction with architectural acoustics. With the aid of wave field synthesis (WFS), newly proposed variations on orchestral layouts are tested virtually using a 64-channel WFS array. Each layout is objectively and subjectively compared for determination of which layout could optimize the sound of the orchestra and revitalize the excitement of the performance.

  4. Urban Sound Ecologies

    DEFF Research Database (Denmark)

    Groth, Sanne Krogh; Samson, Kristine

    2013-01-01

    Within recent years, there has been a renewed focus on sound in urban environments. From sound installations in public space to sound festivals in alternative settings, we find a common interest in sound art relating to the urban environment. Artworks or interventions presented in such contexts...... share the characteristics of site specificity. However, this article will consider the artwork in a broader context by re-examining how sound installations relate to the urban environment. For that purpose, this article brings together ecology terms from acoustic ecology of the sound theories of the...... 1970s while developing them into recent definitions of ecology in urban studies. Finally, we unfold our framing of urban sound ecologies with three case analyses: a sound intervention in Berlin, a symphony for wind instruments in Copenhagen and a video walk in a former railway station in Kassel. The...

  5. Symphonic Characters in Dance Choreography%论舞蹈的“交响性”

    Institute of Scientific and Technical Information of China (English)

    邹罡

    2012-01-01

    Symphony, as a method of dance choreography, is widely used in difference dance creations. It not only helps to stress the dance rhythems, but also enlarge the tension for dance expressions.%无论是舞剧作品还是舞蹈作品,大部分舞蹈编导都会利用舞蹈音乐的“交响性”进行编舞,也有人称之为“交响编舞”。舞蹈的“交响性”既能满足和强化舞蹈节奏的需要,又能极大地拓展舞蹈抒情达意的空间,并且还能激发舞蹈的艺术生命力,调动舞蹈表演者的激情,增强舞蹈艺术的表现力。

  6. Birmingham-Britain’s Second Largest City

    Institute of Scientific and Technical Information of China (English)

    汪伦

    2009-01-01

    Surrounded by several motorways, separated by canals and with many modem shopping centres, Birmingham seems like a huge maze (迷宫). (1) Best to.set your bearings on the great Council House 19th-century buildings which is located in the heart of town. This area consists of Victoria and Chamberlain Squares, which are the most attractive architecture in the city. To the west are Centenary Square, the International Convention Centre and Symphony Hall, as well as the popular bars and cafes. To the northwest is the colourful Jewellery Quarter. In the southeast of the area are the Pallasades and Pavilions shopping centres and the City Plaza.

  7. Polarized Synchrotron Emissivities and Absorptivities for Relativistic Thermal, Power-Law, and Kappa Distribution Functions

    CERN Document Server

    Pandya, Alex; Chandra, Mani; Gammie, Charles F

    2016-01-01

    Synchrotron emission and absorption determine the observational appearance of many astronomical systems. In this paper, we describe a numerical scheme for calculating synchrotron emissivities and absorptivities in all four Stokes parameters for arbitrary gyrotropic electron distribution functions, building on earlier work by Leung, Gammie, and Noble. We use this technique to evaluate the emissivities and the absorptivities for a thermal (Maxwell-J\\"uttner), isotropic power-law, and isotropic kappa distribution function. The latter contains a power-law tail at high particle energies that smoothly merges with a thermal core at low energies, as is characteristic of observed particle spectra in collisionless plasmas. We provide fitting formulae and error bounds on the fitting formulae for use in codes that solve the radiative transfer equation. The numerical method and the fitting formulae are implemented in a compact C library called ${\\tt symphony}$. We find that: the kappa distribution has a source function th...

  8. SEMIOTIC MOTIVES IN Y. YEVTUSHENKO’S POEM “MUM AND THE NEUTRON BOMB” Culturological Notes

    Directory of Open Access Journals (Sweden)

    Inna KALITA

    2014-05-01

    Full Text Available The article presents the analysis of some epochal symbols introduced in Y. Yevtushenko’s poem “Mum and the Neutron Bomb” (1982. Creative approaches and their realization made by the author are shown regarding the common course of the 60’s traditions which the author was outstandingly following. The variety of perspectives and the specifics of expression means allow to compare the poem with a symphony. Semiotic approach enables the analysis of symbols introduced considering the epochal connections and the author’s creative self-realization, it also helps to stress the common and the particular from the different perception aspects (1 creation time – the 20th century: reading time the 20th century and (2 creation time – the 20th century: reading time the 21st century.

  9. Celebrating Einstein

    Science.gov (United States)

    Shapiro Key, Joey; Yunes, Nicolas

    2013-04-01

    The Gravity Group at Montana State University (MSU) hosted Celebrating Einstein, a free public arts and multimedia event celebrating Einstein and his ideas in Bozeman, Montana April 2-6, 2013. The products of our efforts are now available to any party interested in hosting a similar event. Celebrating Einstein is a truly interdisciplinary effort including art, film, dance, music, physics, history, and education. Events included a black hole immersive art installation, a series of public talks by physicists, and Einstein lessons in the public schools leading up to a live free public multimedia performance including a professional dance company, a live interview with a renowned physicist, and an original score composed for the MSU student symphony to be performed with an original film produced by the Science and Natural History film program at MSU. This project is funded by the Montana Space Grant Consortium, Montana State University, and the National Science Foundation.

  10. Online calculation of the decay heat of assemblies at the Fast Flux Test Facility

    International Nuclear Information System (INIS)

    The Fast Flux Test Facility (FFTF) is utilized by the US Department of Energy and the international community as a fast reactor research tool. Its use includes, among other things, the irradiation testing of nuclear reactor fuels and materials required for the development of commercial liquid metal reactors. The decay heat rate of assemblies irradiated in the FFTF is an important parameter in establishing the transportation, examination, and storage of irradiated assemblies. The decay heat program which is maintained on a Cray super computer along with a Symphony speadsheet program running on a personal computer (PC) were created to accommodate this need. This unique synthesis provides a method of combing the capabilities of a mainframe computer with those of a PC

  11. HEALTH CARE ECONOMICS IN ROMANIA--DYNAMICS AND EVOLUTION.

    Science.gov (United States)

    Tamba, B I; Azoicăi, Doina; Druguş, Daniela

    2016-01-01

    Health economics refers to the analysis of medical institutions considering their economic and social efficacy, but also the regularity and the relationships that govern the phenomena and the processes from the field of health with the final purpose of achieving better results with the minimum of resources; it represents the study of health price in its complexity. The economics of the population's health needs and in particular the health needs in case of the poor groups of the population, consider health to be the main component of global human vulnerability. Health economics tries to change the simple interpretation of health price and disease cost into a wider consideration of a system administration similar to educational and social economics and the study of health in the context of the multiple specializations of the macro economy of the national group, as it is an instrument in the country's great economics symphony. PMID:27125091

  12. Introduction

    DEFF Research Database (Denmark)

    Steijn, Arthur; Ion Wille, Jakob

    2013-01-01

    In the spring of 2013 students from the Royal Danish Academy of Fine Arts, School of Design and Malmö University were engaged in programs part of the EU project, Musical Experience Design. The EU project is seeking development of innovative experiences within the context of live classical music...... concerts. Three cultural institutions in the Øresund region, Malmö Symphony Orchestra, The Royal Danish Theatre, and Copenhagen Phil, are functioning as laboratories for developing and testing new concepts. Concept development in the project focuses mainly on artistic and technological productions and...... products, as well as sustainable business models. The main concern of the two educational programs was to examine the live format of symphonic music and create visual and/or interaction design that in one way or the other would enrich the experience of the live concert. The key question of the program at...

  13. Can ensemble condition in a hall be improved and measured?

    DEFF Research Database (Denmark)

    Gade, Anders Christian

    1988-01-01

    In collaboration with the Danish Broadcasting Corporation an extensive series of experiments has been carried out in The Danish Radio Concert Hall with the practical purpose of trying to improve the ensemble conditions on the platform for the resident symphony orchestra. First, a series of...... ceiling reflectors; and (c) changing the position of the orchestra on the platform. These variables were then tested in full scale experiments in the hall including subjective evaluation by the orchestra in order to verify their effects under practical conditions. New objective parameters, which showed...... very high correlations with the subjective data, also made it possible to compare the improvements with conditions as recently measured in famous European Halls. Besides providing the needed results, the experiments also shed some light on how musicians change their criteria for judging acoustic...

  14. Beethoven's deafness, the defiance of a genius

    Directory of Open Access Journals (Sweden)

    Bento, Ricardo Ferreira

    2009-09-01

    Full Text Available Introduction: Ludwig van Beethoven, one of the greatest composers in History, was tormented for his whole life by a progressive deafness without definitive diagnosis. Many authors published studies about the etiologic possibilities of the deafness of the music genius with different explanations about his auditory loss. In this work, the author discusses the implications of Beethoven's progressive deafness to the creation of his word, as well as etiologic assumptions of his disease. Would Beethoven have had the same ingeniousness he showed in his symphonies if he did not have hypacusis and tinnitus? What is the influence of his deafness on his work and life? Could he have had a more precise diagnosis and specially a treatment nowadays? Would we have the brilliant composer if he had deafness today? We surely could not have!

  15. Auralization of an orchestra using multichannel and multisource technique (A)

    DEFF Research Database (Denmark)

    Vigeant, Michelle C.; Wang, Lily M.; Rindel, Jens Holger

    2006-01-01

    were obtained for every orchestral part of two symphonies at the Technical University of Denmark. Five-channel auralizations were then created for each instrument, located at its typical position on-stage in a concert hall, by convolving five impulse responses from sources that each represent......, illustrating the perceived changes in realism, source width and depth, and source separation between the output of this full orchestral mix of multichannel auralizations and other auralization methods, including the following: (i) a mix of single-channel auralizations from each instrument, and auralizations...... made with a single channel orchestral anechoic recording using (ii) a surface source and (iii) a single omni-directional source. [Work supported by the National Science Foundation.]...

  16. Sirocco - Fukushima Forecast Description

    International Nuclear Information System (INIS)

    SYMPHONIE-NH is the non-hydrostatic ocean model following the Boussinesq hydrostatic SYMPHONIE-2010 model developed by the Sirocco system team (CNRS and Toulouse University). Both are using an Arakawa type finite difference method for the C grid. The R and D team generally gives priority to a physically based approach of modelling (global conservation of the mechanical energy, consistency of pressure and density, accuracy of the bottom pressure torque,...) that tends to favour low order and robust numerical schemes. Most of the physical and numerical options (Non-Hydrostatic, free surface, generalised coordinates combined to an ALE method,...) are particularly suitable for the coastal area. At the request of the International Atomic Energy Agency (IAEA, March 14, 2011), SIROCCO is delivering every day a real time 6-day forecast bulletin of the dispersion in seawater of radionuclides emitted by the Fukushima nuclear plant. The simulations are based on the S2010.18 release of the 3D SIROCCO ocean circulation model. The system is operational since March 24 and the bulletin is available on an 'open-access' basis since March 28. The model uses a stretched horizontal grid with a variable horizontal resolution: from 600 m x 600 m at the nearest grid point from Fukushima, to 5 km x 5 km offshore. The initial fields (T, S, U, V, SSH) and the lateral open boundary conditions are provided by the Mercator PSY4V1R3 system (one field per day, horizontal resolution 1/12 deg. x 1/12 deg.). At the sea surface, the ocean model is forced by the meteorological fluxes delivered every 3 hours by ECMWF.i The tidal forcing at the lateral open boundaries is provided by the T-UGO model, implemented for this purpose by the SIROCCO team on the Japanese Pacific coast. Some details are given on the methodology: Bathymetry, Initialization and large scale forcing, Tides, Atmospheric forcing, Forecast protocol, and Scenario for radioactive tracers

  17. Outreach for Families and Girls- Astronomy at Outdoor Concerts and at Super Bowl or Halloween Star Parties

    Science.gov (United States)

    Lubowich, Donald A.

    2011-05-01

    Bring telescope to where the people are! Music and Astronomy Under the Stars (MAUS) is a NASA-funded as astronomy outreach program at community parks and music festivals (1000 - 25,000 people/event). While there have been many astronomy outreach activities and telescope observations at sidewalks and parks, this program targets a different audience - music lovers who are attending concerts in community parks or festivals. These music lovers who may not have visited science museums, planetariums, or star parties are exposed to telescope observations and astronomy information with no additional travel costs. MAUS includes solar observing, telescope observations including a live imaging system, an astronomical video, astronomy banners/posters, and hands-on activities. MAUS increased awareness, engagement, and interest in astronomy at classical, pop, rock, and ethnic music concerts. Since 2009 over 50,000 people have participated in these outreach activities including a significant number of families and young girls. In addition to concerts in local Long Island parks, there were MUAS events at Tanglewood (summer home of the Boston Symphony Orchestra), Jazz in Central Park, and Astronomy Night on the National Mall (co-sponsored by the White House Office of Science and Technology Policy). In 2011 MUAS will be expanded to include Ravinia (summer home of the Chicago Symphony Orchestra), the Newport Folk Festival, and the Bethel Woods Center for the Arts (site of the 1969 Woodstock festival). According to our survey results, music lovers became more informed about astronomy. Expanding Hofstra University's successful outreach programs, I propose the creation of a National Halloween Stars event targeting children and a National Super Bowl Star Party targeting girls, women, and the 2/3 of Americans who do not watch the Super Bowl. This can be combined with astronomers or amateur astronomers bringing telescopes to Super Bowl parties for football fans to stargaze during

  18. Cinétique de la troponine Ic et valeurs seuils pour le diagnostic d'infarctus du myocarde après chirurgie cardiaque sous circulation extracorporelle

    Science.gov (United States)

    Kallel, Samy; Jarraya, Anwar; Ellouze, Maged; Frikha, Imed; Karoui, Abbdelhamid

    2012-01-01

    Introduction L'objectif de ce travail était d’étudier la cinétique de la Troponine Ic (TnIc) après chirurgie cardiaque sous circulation extracorporelle (CEC) et établir des valeurs seuils de TnIc pour le diagnostic d'infarctus du myocarde (IDM) post opératoire. Il s'agissait d'une étude prospective type cohorte observationnelle. Méthodes Nous avons inclus 37 patients âgés de plus de 18 ans proposés pour chirurgie valvulaire ou pontage aorto coronarien sous CEC. Nous avons suivi la cinétique de TnIc par des dosages immunoenzymatique sur mini-vidas® avant et après la CEC, à H4 et H12 postopératoire puis tous les jours les 4 premiers jours. Le cutoff pour le diagnostic d'IDM post opératoire a été défini comme la valeur moyenne de troponine + deux déviations standards des patients indemnes de complications cardiaques. Résultats Les valeurs de TnIc en préopératoire étaient toutes inférieures au seuil de détection de la méthode de dosage (<0,01µg/l). Les valeurs de TnIc augmentent en postopératoire immédiat pour atteindre un maximum à H4 puis diminuent progressivement pour se normaliser après 4 à 5 jours. Les valeurs seuils ont été déterminées pour H0, H4,H12, H24, H48, H72, H96 et ont été respectivement 1.36, 2.58, 3.1, 3.23, 2.13, 1.53, 1.17 pour la chirurgie coronaire et 3.75, 5.39, 4.22, 3.41, 1.65, 1.3 1.19 pour la chirurgie valvulaire. Conclusion La connaissance de la cinétique de TnIc lors de chirurgie cardiaque non compliquée et la fixation de valeur seuil ou Cutoff permet aux cliniciens de distinguer entre dommage myocardique secondaire à la chirurgie et IDM. PMID:23396754

  19. Pharmaceuticals, hormones and bisphenol A in untreated source and finished drinking water in Ontario, Canada - Occurrence and treatment efficiency

    Energy Technology Data Exchange (ETDEWEB)

    Kleywegt, Sonya; Pileggi, Vince [Standards Development Branch, Ontario Ministry of the Environment, 40 St. Clair Avenue West, Toronto, Ontario, M4V 1M2 (Canada); Yang, Paul, E-mail: paul.yang@ontario.ca [Laboratory Services Branch, Ontario Ministry of the Environment, 125 Resources Road, Etobicoke, Ontario, M9P 3V6 (Canada); Hao Chunyan; Zhao Xiaoming [Laboratory Services Branch, Ontario Ministry of the Environment, 125 Resources Road, Etobicoke, Ontario, M9P 3V6 (Canada); Rocks, Carline [Environmental Monitoring and Reporting Branch, Ontario Ministry of the Environment, 125 Resources Road, Etobicoke, Ontario, M9P 3V6 (Canada); Thach, Serei [Laboratory Services Branch, Ontario Ministry of the Environment, 125 Resources Road, Etobicoke, Ontario, M9P 3V6 (Canada); Cheung, Patrick; Whitehead, Brian [Environmental Monitoring and Reporting Branch, Ontario Ministry of the Environment, 125 Resources Road, Etobicoke, Ontario, M9P 3V6 (Canada)

    2011-03-15

    The Ontario Ministry of the Environment (MOE) conducted a survey in 2006 on emerging organic contaminants (EOCs) which included pharmaceuticals, hormones and bisphenol A (BPA). The survey collected 258 samples over a 16 month period from selected source waters and 17 drinking water systems (DWSs), and analyzed them for 48 EOCs using liquid chromatography-tandem mass spectrometry (LC-MS/MS) and isotope dilution mass spectrometry (IDMS) for the highest precision and accuracy of analytical data possible. 27 of the 48 target EOCs were detected in source water, finished drinking water, or both. DWSs using river and lake source water accounted for > 90% detections. Of the 27 EOCs found, we also reported the first detection of two antibiotics roxithromycin and enrofloxacin in environmental samples. The most frequently detected compounds ({>=} 10%) in finished drinking water were carbamazepine (CBZ), gemfibrozil (GFB), ibuprofen (IBU), and BPA; with their concentrations accurately determined by using IDMS and calculated to be 4 to 10 times lower than those measured in the source water. Comparison of plant specific data allowed us to determine removal efficiency (RE) of these four most frequently detected compounds in Ontario DWSs. The RE of CBZ was determined to be from 71 to 93% for DWSs using granulated activated carbon (GAC); and was 75% for DWSs using GAC followed by ultraviolet irradiation (UV). The observed RE of GFB was between 44 and 55% in DWSs using GAC and increased to 82% when GAC was followed by UV. The use of GAC or GAC followed by UV provided an RE improvement of BPA from 80 to 99%. These detected concentration levels are well below the predicted no effect concentration or total allowable concentration reported in the literature. Additional targeted, site specific comparative research is required to fully assess the effectiveness of Ontario DWSs to remove particular compounds of concern. - Research Highlights: {yields} Occurrence and typical range of 45

  20. Pharmaceuticals, hormones and bisphenol A in untreated source and finished drinking water in Ontario, Canada - Occurrence and treatment efficiency

    International Nuclear Information System (INIS)

    The Ontario Ministry of the Environment (MOE) conducted a survey in 2006 on emerging organic contaminants (EOCs) which included pharmaceuticals, hormones and bisphenol A (BPA). The survey collected 258 samples over a 16 month period from selected source waters and 17 drinking water systems (DWSs), and analyzed them for 48 EOCs using liquid chromatography-tandem mass spectrometry (LC-MS/MS) and isotope dilution mass spectrometry (IDMS) for the highest precision and accuracy of analytical data possible. 27 of the 48 target EOCs were detected in source water, finished drinking water, or both. DWSs using river and lake source water accounted for > 90% detections. Of the 27 EOCs found, we also reported the first detection of two antibiotics roxithromycin and enrofloxacin in environmental samples. The most frequently detected compounds (≥ 10%) in finished drinking water were carbamazepine (CBZ), gemfibrozil (GFB), ibuprofen (IBU), and BPA; with their concentrations accurately determined by using IDMS and calculated to be 4 to 10 times lower than those measured in the source water. Comparison of plant specific data allowed us to determine removal efficiency (RE) of these four most frequently detected compounds in Ontario DWSs. The RE of CBZ was determined to be from 71 to 93% for DWSs using granulated activated carbon (GAC); and was 75% for DWSs using GAC followed by ultraviolet irradiation (UV). The observed RE of GFB was between 44 and 55% in DWSs using GAC and increased to 82% when GAC was followed by UV. The use of GAC or GAC followed by UV provided an RE improvement of BPA from 80 to 99%. These detected concentration levels are well below the predicted no effect concentration or total allowable concentration reported in the literature. Additional targeted, site specific comparative research is required to fully assess the effectiveness of Ontario DWSs to remove particular compounds of concern. - Research Highlights: → Occurrence and typical range of 45 selected

  1. 关联信息在社交网络中传播的竞争模型%Modeling Cooperation and Competition of Information Diffusion in Online Social Network

    Institute of Scientific and Technical Information of China (English)

    王云驰; 邓倩妮

    2015-01-01

    In Online Social Networks(OSNs) multiple contagions not only propagate through the network but also interact with each other at the same time. In order to understand the diffusion process of contagions it is necessary to study how different contagions interact. Most of prior work considered individual contagions as independent and thus spreading in isolation. In this paper, an analo-gy is made between OSNs and biology systems. The interaction among contagions could be regarded as the competing among spe-cies. An Interaction Diffusion Model(IDM) is proposed, which is based on the classic reaction diffusion equation in dynamic biology systems to describe and predict the interactions among multiple contagions. Two real datasets collected from Github are used to tes-tify the predicting performance of the IDM model. Experimental results show that IDM model outperforms the compared models at predicting accuracy.%在社交网络(OSNs)中,各个信息不仅独立通过网络传播,而是在传播的过程中彼此进行交互。为了理解社交网络中相关联信息的扩散过程,需要研究不同的信息在传播过程中是如何交互的。目前,大部分的研究都认为不同信息的传播过程之间相互独立。将社交网络和具有食物链的生态系统进行了类比,信息之间的相互作用可以被视为物种之间的竞争,基于经典的动态生态系统的反应扩散模型,建立起了IDM模型。从Github上收集了两个真实的数据集,并通过实验结果证明了:相对于Lotka-Volterra模型模型,IDM模型具有更优秀的预测性能。

  2. Isotope dilution mass spectrometry as the primary method of measurement for the amount of matter. Application to cadmium determination in biological materials and comparison with instrumental neutron activation analysis

    International Nuclear Information System (INIS)

    A primary method of measurement as defined by the Consultative Committee on the Quantity of Matter (Comite Consultatif pour la Quantite de Matiere, CCQM) of the International Bureau of Weights and Measurements (Bureau International des Poids et Mesures, BIPM), is one whose measurement process is perfectly known, has valid theoretical foundations and is fully described and answers to an equation that relates what is measured with what is intended to be measured without any significant empirical correction factors. It is also a method that has insignificant systematic errors, where only magnitudes from the International System of Units (SI) are used and where, preferably, the uncertainties are small ones. They are, therefore, procedures that do not need instrumental calibration. The absolute methods of measurement allow a chain of traceability to be formed between the result obtained and the magnitude of the SI assigned to what is measured. So the results are said to be traceable to the SI. One of the methods that meets these requirements and is recognized as the primary method by the CCQM is Isotope Dilution Mass Spectrometry (IDMS). Through a project of Technical Cooperation with the International Atomic Energy Agency in the area of Chemical Metrology, the CCHEN obtained training in CIEMAT, Spain, in IDMS and its applications to the analysis of biological samples. This work describes the first experience carried out entirely in Chilean laboratories, applying IDMS to the determination of cadmium in the biological reference materials Oyster Tissue 15566-A from the NIST, United States, Dogfish Liver, DOLT-2 from the NRC-CNRC, Canada and Poplar Leaves GBW07604 from the NRCC, China. The samples were traced with an isotope enriched spike 111Cd and then shaken to obtain the isotopic exchange. Once dissolved, the isotopic relationship 111Cd/114Cd was determined in the samples using mass spectrometry with plasma source. These results were compared with those obtained using

  3. COOPERATIVE LAND REUSE PROGRAM

    Energy Technology Data Exchange (ETDEWEB)

    Unknown

    1999-07-30

    The objective of this study was to determine what financial return, if any, DOE would realize if they invest solely in removal of the asbestos from these three Hanford steam plants and the associated large bore distribution piping at the site. Once the asbestos was removed the strategy was to bring in companies that specialize in salvage and material re-use and have them remove, at no cost to DOE, the plants and the associated large bore piping. The salvage companies we contacted had said that if they didn't have to remove asbestos, they may be able to realize enough value from these plants to offset their demolition and/or dismantling cost. The results were not what we expected but they do offer DOE some favorable financial alternatives to their present approach. The study concluded that there was very little salvage and/or re-use value remaining in the steam plant material that could be used to offset the demolition and/or dismantling cost. The notable exception to this is the removal of the 24 inch steam piping that runs from 200E to 200W areas (see IDM executive summary under Dismantling cost). It is estimated that the re-use value of the 24-inch piping would more than pay for the dismantling cost of this piping. On a more favorable note, it does appear as though the cost of conventional demolition can be reduced by a factor of 3 to 5 if the asbestos is removed first and the demolition is performed using competitive and commercial practices. Both estimates in this study are similar except that IDM did not include floor slab removal nor remove the same quantity of piping. This is why we are using a range of 3 to 5 as a reduction factor. The IDM estimate (using union labor) for demolition after removal of asbestos was approximately $1.5M versus $10.0M for accomplishing the work using Hanford practices and rates.

  4. Sextant. Une infrastructure de données géographiques marines et littorales

    OpenAIRE

    Satra Le Bris, Catherine; Conquet, Florence; Meillon, Julien; Quimbert, Erwann; Treguer, Mickael

    2015-01-01

    Aux niveaux national et européen, en mode opérationnel ou recherche, des produits de données d'observations sont développés afin de qualifier, packager et synthétiser de façon homogène les données marines à destination des utilisateurs en aval des centres de données. L’unité IDM d’Ifremer a développé une infrastructure de données géographiques marines et littorales, appelée Sextant (http://sextant.ifremer.fr), qui permet de documenter, diffuser et promouvoir ces produits, à destination de...

  5. Secondary Uses of Personal Identity Information: Policies, Technologies and Regulatory Framework

    DEFF Research Database (Denmark)

    Adjei, Joseph K.; Olesen, Henning

    Although personal identity information must primarily be used for protecting and promoting the physical needs of individuals, it has also become central to the business models of the digital age due to its use for other secondary purposes, resulting in various innovative identity management (Id......M) solutions in OECD countries. Nonetheless, developing countries have still not been able to address basic identification challenges such as civil registration, real-time credentials verifications, etc. This paper discusses a means of communicating identity-related concepts to policy-makers, technologists......, credential issuers and other stakeholders by addressing core issues relating to secondary use of personal information. The results of a stakeholder workshop in Ghana on secondary use of personal information are presented by stating the core issues and recommendations. We propose the adaptation and...

  6. Performance de agências bancárias: aplicando DEA a múltiplas perspectivas do desempenho

    Directory of Open Access Journals (Sweden)

    Marcelo Alvaro da Silva Macedo

    2009-01-01

    Full Text Available In this article, will be applied the DEA methodology in the balanced perspective indicators (equal weights of the Balanced Scorecard (BSC, in order to defi ne effi cient and ineffi cient units. For this, we analyze 38 retail segment agencies, of a single national institution, which is ranked as one of the largest Brazilian banks. The results show the Multicriterial Performance Index - IDM, which represents the consolidated index of multicriterial performance of each agencies under analysis, considering the fi nancial, the operational, the customer and the staff performance perspectives. We can see, yet, at the 10 % level of signifi cance, that the performance is related to the size of agencies, because the average multicriterial performance of 10 major agencies is higher than the 10 smaller agencies. This refl ects the scale economies that exist in the operations of agencies.

  7. Congestion Reduction Using Ad hoc Message Dissemination in Vehicular Networks

    CERN Document Server

    Hewer, Thomas D

    2008-01-01

    Vehicle-to-vehicle communications can be used effectively for intelligent transport systems (ITS) and location-aware services. The ability to disseminate information in an ad-hoc fashion allows pertinent information to propagate faster through the network. In the realm of ITS, the ability to spread warning information faster and further is of great advantage to the receivers of this information. In this paper we propose and present a message-dissemination procedure that uses vehicular wireless protocols for influencing traffic flow, reducing congestion in road networks. The computational experiments presented in this paper show how an intelligent driver model (IDM) and car-following model can be adapted to 'react' to the reception of information. This model also presents the advantages of coupling together traffic modelling tools and network simulation tools.

  8. Ammonium generation during SRAT cycle

    International Nuclear Information System (INIS)

    During the IDMS noble-metal demonstration runs ammonium nitrate deposition was found in the vessel vent system of the feed preparation area. In the bench-scale experiments of studying the hydrogen generation during the sludge treatment cycle, ammonium ion production was also monitored. It was found that: During a simulation of the DWPF Cold Chemical Runs SRAT cycle no detectable amount of ammonium ions was generated when treating a non-noble-metal containing sludge simulant according to the nitric acid flowsheet. Ammonium ions were generated during the SRAT-SME cycle when treating the noble-metal containing sludge with either formic acid or nitric acid/late-washing PHA. This is due to the reaction between formic acid and nitrate catalyzed by the noble metals in the sludge simulant. Ammonium ion production closely followed the hydrogen evolution from the catalytic decomposition of formic acid. This report summarizes the results of the production of ammonia during the SRAT cycle

  9. Errors of DWPF frit analysis: Final report

    International Nuclear Information System (INIS)

    Glass frit will be a major raw material for the operation of the Defense Waste Processing Facility. The frit will be controlled by certificate of conformance and a confirmatory analysis from a commercial analytical laboratory. The following effort provides additional quantitative information on the variability of frit chemical analyses at two commercial laboratories. Identical samples of IDMS Frit 202 were chemically analyzed at two commercial laboratories and at three different times over a period of four months. The SRL-ADS analyses, after correction with the reference standard and normalization, provided confirmatory information, but did not detect the low silica level in one of the frit samples. A methodology utilizing elliptical limits for confirming the certificate of conformance or confirmatory analysis was introduced and recommended for use when the analysis values are close but not within the specification limits. It was also suggested that the lithia specification limits might be reduced as long as CELS is used to confirm the analysis

  10. Cinétique de la troponine Ic et valeurs seuils pour le diagnostic d'infarctus du myocarde après chirurgie cardiaque sous circulation extracorporelle

    OpenAIRE

    Kallel, Samy; Jarraya, Anwar; Ellouze, Maged; Frikha, Imed; Karoui, Abbdelhamid

    2012-01-01

    Introduction L'objectif de ce travail était d’étudier la cinétique de la Troponine Ic (TnIc) après chirurgie cardiaque sous circulation extracorporelle (CEC) et établir des valeurs seuils de TnIc pour le diagnostic d'infarctus du myocarde (IDM) post opératoire. Il s'agissait d'une étude prospective type cohorte observationnelle. Méthodes Nous avons inclus 37 patients âgés de plus de 18 ans proposés pour chirurgie valvulaire ou pontage aorto coronarien sous CEC. Nous avons suivi la cinétique d...

  11. Approaches to the ISO/IEC 17025 accreditation for Pu and U accountancy analysis

    International Nuclear Information System (INIS)

    The quality control section of Plutonium Fuel Development Center (PFDC) of Japan Atomic Energy Agency has been analyzing isotopic compositions by Mass Spectrometry as well as content by Isotope Dilution Mass Spectrometry (IDMS) of plutonium and uranium in nuclear materials. Along with establishing and managing the quality assurance system, ensuring the reliability of the analysis data is important. PFDC has been establishing the quality management system with ISO9001. ISO9001 consists of management requirements for quality system of organizations. While ISO/IEC 17025 consists of technical requirements for the competence of testing and calibration laboratories in addition to the management requirements. The quality control section addressed technical improvement to improve further reliability of analysis quality and we have accredited for ISO/IEC 17025 of isotopic compositions and content of plutonium and uranium in nuclear materials in March 2010. In this presentation, we report our approaches to the ISO/IEC 17025 accreditation and operation status. (author)

  12. Inline monitoring of laser processing: new industrial results with the low coherence interferometry sensor approach

    Science.gov (United States)

    Kogel-Hollacher, Markus; Schoenleber, Martin; Bautze, Thibault; Moser, Rüdiger; Strebel, Matthias

    2016-03-01

    The introduction of inline coherent imaging technologies as a sensor for the laser materials processing is accompanied by the integration into several applications. One of these is the measurement of the depth of the vapor capillary for laser welding applications, now allowing to keep record of the welding depth with an accuracy of micrometers and a sub millisecond temporal resolution. The broader achievement is the closed-loop control of the welding depth that was not available in industrial environments till now due to the lack of an adequate sensor. Further use includes the acquisition of 3D images around the laser process itself, allowing for coaxial integration of pre- and post-process sensors. These applications are demonstrated by using the In-Process Depth Meter (IDM).

  13. The cloud storage service bwSync&Share at KIT

    CERN Document Server

    CERN. Geneva

    2014-01-01

    The Karlsruhe Institute of Technology introduced the bwSync&Share collaboration service in January 2014. The service is an on-premise alternative to existing public cloud storage solutions for students and scientists in the German state of Baden-Württemberg, which allows the synchronization and sharing of documents between multiple devices and users. The service is based on the commercial software PowerFolder and is deployed on a virtual environment to support high reliability and scalability for potential 450,000 users. The integration of the state-wide federated identity management system (bwIDM) and a centralized helpdesk portal allows the service to be used by all academic institutions in the state of Baden-Württemberg. Since starting, approximately 15 organizations and 8,000 users joined the service. The talk gives an overview of related challenges, technical and organizational requirements, current architecture and future development plans.

  14. Pre-concentration and determination of amitriptyline residues in waste water by ionic liquid based immersed droplet microextraction and HPLC

    Institute of Scientific and Technical Information of China (English)

    M.T. Hamed Mosavian; Z. Es'haghi; N. Razavi; S. Banihashemi

    2012-01-01

    This paper describes a new approach for the determination of amitriptyline in wastewater by ionic liquid based immersed droplet microextraction (IL-IDME) prior to highperformance liquid chromatography with ultraviolet detection. 1-Hexyl-3-methylimidazolium hexafluorophosphate ([C6MIM][PF6]) was used as an ionic liquid. Various factors that affect extraction, such as volume of ionic liquid, stirring rate, extraction time, pH of the aqueous solution and salting effect, were optimized. The optimal conditions were as follows: microextraction time, 10 min; stirring rate, 720 rpm; pH, 11; ionic drop volume, 100 uL; and no sodium chloride addition. In quantitative experiments the method showed linearity in a range from 0.01 to 10 ug/mL, a limit of detection of 0.004 ug/mL and an excellent pre-concentration factor (PF) of 1100. Finally, the method was successfully applied to the determination of amitriptyline in the hospital wastewater samples.

  15. Improvement of the interfacial Dzyaloshinskii-Moriya interaction by introducing a Ta buffer layer

    International Nuclear Information System (INIS)

    We report systematic measurements of the interfacial Dzyaloshinskii-Moriya interaction (iDMI) by employing Brillouin light scattering in Pt/Co/AlOx and Ta/Pt/Co/AlOx structures. By introducing a tantalum buffer layer, the saturation magnetization and the interfacial perpendicular magnetic anisotropy are significantly improved due to the better interface between heavy metal and ferromagnetic layer. From the frequency shift between Stokes- and anti-Stokes spin-waves, we successively obtain considerably larger iDM energy densities (Dmax = 1.65 ± 0.13 mJ/m2 at tCo = 1.35 nm) upon adding the Ta buffer layer, despite the nominally identical interface materials. Moreover, the energy density shows an inverse proportionality with the Co layer thickness, which is the critical clue that the observed iDMI is indeed originating from the interface between the Pt and Co layers

  16. Trace element speciation in the environment

    International Nuclear Information System (INIS)

    The production of methylated heavy metal species in the ocean was reviewed and shown to be correlated with biological parameters demonstrating them to be of biogenic origin. Methods for the determination of the species were discussed. The potential for the use of isotopic spiking either in 'species specific' or 'non-species specific' formats was identified as a valuable tool in the struggle for accuracy, specificity and precision in speciation analysis. The value of using a size exclusion chromatographic method in conjunction with non-species specific spiking IDMS was highlighted with an example illustrating the molecular mass fractions associated with halogenated species from a humic sample. Additional recommendations that the Agency might wish to consider when evaluating its potential role as a service to Member States engaged in speciation activities are also given

  17. CASE REPORT OF BECKWITH-WIEDEMANN SYNDROME

    Directory of Open Access Journals (Sweden)

    Ravikanth

    2014-06-01

    Full Text Available In 1963 Beckwith presented a report on the first patient with extreme cytomegaly of adrenal cortex, hyperplasia of kidneys as well as pancreas and Leydig cell hyperplasia. Wiedemann completed description of the new syndrome by adding umbilical hernia and macroglossia. The diagnosis is made based on the clinical signs of omphalocele. [7] or some other umbilical deformity, macroglossia. [8] congenital asymmetry, visceromegaly (liver, pancreas, and kidneys. Newborn with macrosomia, macroglossia first differential diagnosis are infant of diabetic mother, congenital hypothyroidism etc. IDM can be identified easily with history of maternal diabetes. So congenital hypothyroidism is next common diagnosis and will be treated as hypothyroidism. If TSH, T3 and T4 are not clearly indicative of congenital hypothyroidism next consider the Beckwith Wiedemann syndrome in differential diagnosis of large for gestational age.

  18. Perturbation and Stability Analysis of the Multi-Anticipative Intelligent Driver Model

    Science.gov (United States)

    Chen, Xi-Qun; Xie, Wei-Jun; Shi, Jing; Shi, Qi-Xin

    This paper discusses three kinds of IDM car-following models that consider both the multi-anticipative behaviors and the reaction delays of drivers. Here, the multi-anticipation comes from two ways: (1) the driver is capable of evaluating the dynamics of several preceding vehicles, and (2) the autonomous vehicles can obtain the velocity and distance information of several preceding vehicles via inter-vehicle communications. In this paper, we study the stability of homogeneous traffic flow. The linear stability analysis indicates that the stable region will generally be enlarged by the multi-anticipative behaviors and reduced by the reaction delays. The temporal amplification and the spatial divergence of velocities for local perturbation are also studied, where the results further prove this conclusion. Simulation results also show that the multi-anticipative behaviors near the bottleneck will lead to a quicker backwards propagation of oscillations.

  19. The determination of trace technetium-99 in soil samples by negative thermal ionization mass spectrometry and isotope dilution method

    International Nuclear Information System (INIS)

    The Isotope Dilution Mass Spectrometry technology of measuring 99Tc using 97Tc as the spike was developed. The chemical separation procedure of Tc is established, the recovery rate was more than 70% for the overall process. 97 Te was prepared by irradiation of natural Ruthenium metal, then was calibrated by IDMS with 99Tc standard material as the spike. Based on MgCl2 + Ba (OH)2 as the loading reagent, the Negative Thermal Ionization Mass Spectrometry of Technetium was established. which detection sensitivity was pg/g. Then, 99Tc in the soil samples was quantitatively determined by Negative Thermal Ionization Mass Spectrometry and Isotope Dilution Method. The combined standard un- certainty was better than 3%. (authors)

  20. Quantification of four artificial sweeteners in Finnish surface waters with isotope-dilution mass spectrometry.

    Science.gov (United States)

    Perkola, Noora; Sainio, Pirjo

    2014-01-01

    The artificial sweeteners sucralose (SCL), acesulfame (ACS), saccharin (SAC), and cyclamate (CYC) have been detected in environmental waters in Europe and North America. Higher environmental levels are expected in view of the increasing consumption of these food additives. In this study, an isotope-dilution mass spectrometry (IDMS) LC-MS/MS method was developed and validated for quantifying the four artificial sweeteners in boreal lakes (n = 3) and rivers (n = 12). The highest concentrations of ACS, SAC, CYC and SCL were 9,600, 490, 210 and 1000 ng/L, respectively. ACS and SAC were detected in all studied samples, and CYC and SCL in 98% and 56% of the samples. Seasonal trends of ACS and SAC were observed in some rivers. ACS and SCL concentrations in rivers correlated linearly with population equivalents of the wastewater treatment plants in the catchment areas, whereas SAC and CYC concentrations depend more on the source. PMID:24100049

  1. Direct calibration of GC/MS systems using SRM (Standard Reference Material) gas cylinders. Project report, January 1984-August 1985

    International Nuclear Information System (INIS)

    A cryogenic trapping system has been developed for use in calibrating GC/MS systems for the analysis of volatile organic compounds. This system provides for direct Standard Reference Material (SRM) traceability on data generated on gaseous samples. The cryogenic trap is a coil of stainless steel tubing immersed in a cryogen to trap and preconcentrate organic species present in a gaseous sample. The trap also contains a heated injection port for the addition of isotopically labeled compounds for use in isotope dilution measurements. The first part of this research is concerned with the development of IDMS as an independent method for the quantification of analytes in gaseous samples to be used as standards. Results are presented for the determination of bromobenzene in nitrogen at nominal concentrations of 1 and 25 ppb. In the second part of the research, a calibration curve method was developed for using these standards in auditing the performance of GC/MS systems

  2. Sustained effects of integrated COPD management on health status and exercise capacity in primary care patients

    Directory of Open Access Journals (Sweden)

    Annemarije L Kruis

    2010-11-01

    Full Text Available Annemarije L Kruis1, Joan van Adrichem2, Magda R Erkelens2, Huub Scheepers3, Hans in ’t Veen4, Jean WM Muris5, Niels H Chavannes11Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, 2Physiotherapy Center De Beweging, Rotterdam, 3Well-being Medical Center, Bocholtz-Simpelveld, 4Department of Pulmonary Diseases, Sint Franciscus Gasthuis, Rotterdam, 5Department of General Practice, Maastricht University Medical Center, The NetherlandsBackground: Chronic obstructive pulmonary disease (COPD constitutes a growing health care problem worldwide. Integrated disease management (IDM of mild to moderate COPD patients has been demonstrated to improve exercise capacity and health status after one year, but long-term results are currently lacking in primary care.Methods: Long-term data from the Bocholtz study, a controlled clinical trial comparing the effects of IDM versus usual care on health status in 106 primary care COPD patients during 24 months of follow-up, were analyzed using the Clinical COPD Questionnaire (CCQ. In addition, the Kroonluchter IDM implementation program has treated 216 primary care patients with mild to moderate COPD since 2006. Longitudinal six-minute walking distance (6MWD results for patients reaching 24 months of follow-up were analyzed using paired-sample t-tests. In prespecified subgroup analyses, the differential effects of baseline CCQ score, Medical Research Council (MRC dyspnea score, and 6MWD were investigated.Results: In the Bocholtz study, subjects were of mean age 64 years, with an average postbronchodilator forced expiratory volume in one second (FEV1 of 63% predicted and an FEV1/forced vital capacity (FVC ratio of 0.56. No significant differences existed between groups at baseline. CCQ improved significantly and in a clinically relevant manner by 0.4 points over 24 months; effect sizes were doubled in patients with CCQ > 1 at baseline and tripled in patients with MRC dyspnea score

  3. Insulin inhalation: NN 1998.

    Science.gov (United States)

    2004-01-01

    Aradigm Corporation has developed an inhaled form of insulin using its proprietary AERx drug delivery system. The system uses liquid insulin that is converted into an aerosol containing very small particles (1-3 micro in diameter), and an electronic device suitable for either the rapid transfer of molecules of insulin into the bloodstream or localised delivery within the lung. The AERx insulin Diabetes Management System (iDMS), AERx iDMS, instructs the user on breathing technique to achieve the best results. Aradigm Corporation and Novo Nordisk have signed an agreement to jointly develop a pulmonary delivery system for insulin [AERx iDMS, NN 1998]. Under the terms of the agreement, Novo Nordisk has exclusive rights for worldwide marketing of any products resulting from the development programme. Aradigm Corporation will initially manufacture the product covered by the agreement, and in return will receive a share of the overall gross profits from Novo Nordisk's sales. Novo Nordisk will cover all development costs incurred by Aradigm Corporation while both parties will co-fund final development of the AERx device. Both companies will explore the possibilities of the AERx platform to deliver other compounds for the regulation of blood glucose levels. Additionally, the agreement gives Novo Nordisk an option to develop the technology for delivery of agents outside the diabetes area. In April 2001, Aradigm Corporation received a milestone payment from Novo Nordisk related to the completion of certain clinical and product development stages of the AERx drug delivery system. Profil, a CRO in Germany, is cooperating with Aradigm and Novo Nordisk in the development of inhaled insulin. Aradigm and Novo Nordisk initiated a pivotal phase III study with inhaled insulin formulation in September 2002. This 24-month, 300-patient trial is evaluating inhaled insulin in comparison with insulin aspart. Both medications will be given three times daily before meals in addition to basal

  4. Production of Inert Scalars at the $e^+ e^-$ Linear Colliders

    CERN Document Server

    Hashemi, Majid; Najjari, Saereh; Żarnecki, Aleksander F

    2015-01-01

    We investigate the phenomenology of the charged and neutral scalars in Inert Doublet Model (IDM) at future $e^+ e^-$ linear colliders with center of mass energies of 0.5 to 1 TeV and integrated luminosity of 500 $fb^{-1}$. The analysis covers two processes, i.e. $e^{+}e^{-} \\rightarrow H^{+}H^{-}$ and $e^{+}e^{-}\\rightarrow AH$, and consists of a phenomenological signal selection as well as dark matter mass measurement. Several benchmark points are studied with focus on $H^{\\pm} \\rightarrow W^{\\pm}H$ and $A \\rightarrow ZH$ decays. It is concluded that the signal should be well observable in different final states and by combining information from different channels the dark matter mass should also be measurable with a reasonable precision.

  5. Non-parametric Bayesian graph models reveal community structure in resting state fMRI

    DEFF Research Database (Denmark)

    Andersen, Kasper Winther; Madsen, Kristoffer H.; Siebner, Hartwig Roman;

    2014-01-01

    Modeling of resting state functional magnetic resonance imaging (rs-fMRI) data using network models is of increasing interest. It is often desirable to group nodes into clusters to interpret the communication patterns between nodes. In this study we consider three different nonparametric Bayesian...... models for node clustering in complex networks. In particular, we test their ability to predict unseen data and their ability to reproduce clustering across datasets. The three generative models considered are the Infinite Relational Model (IRM), Bayesian Community Detection (BCD), and the Infinite...... Diagonal Model (IDM). The models define probabilities of generating links within and between clusters and the difference between the models lies in the restrictions they impose upon the between-cluster link probabilities. IRM is the most flexible model with no restrictions on the probabilities of links...

  6. Further development of IDGS: Isotope dilution gamma-ray spectrometry

    International Nuclear Information System (INIS)

    The isotope dilution gamma-ray spectrometry (IDGS) technique for determining the plutonium concentration and isotopic composition of highly radioactive spent-fuel dissolver solutions has been further developed. Both the sample preparation and the analysis have been improved. The plutonium isotopic analysis is based on high-resolution, low-energy gamma-ray spectrometry. The plutonium concentration in the dissolver solutions then is calculated from the measured isotopic differences among the spike, the dissolver solution, and the spiked dissolver solution. Plutonium concentrations and isotopic compositions of dissolver solutions analyzed from this study agree well with those obtained by traditional isotope dilution mass spectrometry (IDMS) and are consistent with the first IDGS experimental result. With the current detector efficiency, sample size, and a 100-min count time, the estimated precision is ∼0.5% for 239Pu and 240Pu isotopic analyses and ∼1% for the plutonium concentration analysis. 5 refs., 2 figs., 7 tabs

  7. Brain Network Modelling

    DEFF Research Database (Denmark)

    Andersen, Kasper Winther

    Three main topics are presented in this thesis. The first and largest topic concerns network modelling of functional Magnetic Resonance Imaging (fMRI) and Diffusion Weighted Imaging (DWI). In particular nonparametric Bayesian methods are used to model brain networks derived from resting state f...... for their ability to reproduce node clustering and predict unseen data. Comparing the models on whole brain networks, BCD and IRM showed better reproducibility and predictability than IDM, suggesting that resting state networks exhibit community structure. This also points to the importance of using models, which...... allow for complex interactions between all pairs of clusters. In addition, it is demonstrated how the IRM can be used for segmenting brain structures into functionally coherent clusters. A new nonparametric Bayesian network model is presented. The model builds upon the IRM and can be used to infer...

  8. Identity Management Framework for Internet of Things

    DEFF Research Database (Denmark)

    Mahalle, Parikshit N.

    -configuring capability and is termed as Internet of Things (IoT). The vision of IoT is to connect every object with computing, communication and sensing ability to the Internet. IoT contains varied range of devices from RFID tags, sensor nodes to the even shoes. Thus, IoT enable nomadic collaboration and communication...... between users and devices, between devices themselves and devices to services. Due to rapid technological advancements in the wireless communications, information coming from uncountable applications and services converged on user devices, communication infrastructure and the Internet are integral part...... that are public can be part of the personal space of multiple users at the same time. Secure interaction in and with IoT, secure data management and exchange, authentication, distributed access control and IdM of the devices are the main challenges. The work carried out in the scope of this thesis addresses...

  9. Special Issue: Planar Fully-Depleted SOI technology

    Science.gov (United States)

    Allibert, F.; Hiramoto, T.; Nguyen, B. Y.

    2016-03-01

    We are in the era of mobile computing with smart handheld devices and remote data storage "in the cloud," with devices that are almost always on and driven by needs of high data transmission rate, instant access/connection and long battery life. With all the ambitious requirements for better performance with lower power consumption, the SoC solution must also be cost-effective in order to capture the large, highly-competitive consumer mobile and wearable markets. The Fully-Depleted SOI device/circuit is a unique option that can satisfy all these requirements and has made tremendous progress in development for various applications and adoption by foundries, integrated device manufacturers (IDM), and fabless companies in the last 3 years.

  10. CP violating scalar Dark Matter

    CERN Document Server

    Cordero-Cid, A; Keus, V; King, S F; Moretti, S; Rojas, D; Sokołowska, D

    2016-01-01

    We study an extension of the Standard Model (SM) in which two copies of the SM scalar $SU(2)$ doublet which do not acquire a Vacuum Expectation Value (VEV), and hence are \\textit{inert}, are added to the scalar sector. We allow for CP-violation in the \\textit{inert} sector, where the lightest \\textit{inert} state is protected from decaying to SM particles through the conservation of a $Z_2$ symmetry. The lightest neutral particle from the \\textit{inert} sector, which has a mixed CP-charge due to CP-violation, is hence a Dark Matter (DM) candidate. We discuss the new regions of DM relic density opened up by CP-violation, and compare our results to the CP-conserving limit and the Inert Doublet Model (IDM). We constrain the parameter space of the CP-violating model using recent results from the Large Hadron Collider (LHC) and DM direct and indirect detection experiments.

  11. Present status of quality control on MOX fuel fabrication in JNC

    International Nuclear Information System (INIS)

    Japan Nuclear Cycle Development Institute (JNC has developed MOX fuels for Advanced Thermal Reactor FUGEN and Fast Reactors JOYO and MONJU for these 30 years. The total amount of MOX fuels fabricated in JNC reached to be 157 tons as of the end of March 1999. No fuel pin failure has been found in the fuels loaded in these reactors. This result shows that the fabrication technology of MOX has been established and the quality control has also been done adequately in the fabrication process. This paper describes the basic concept and associated procedures of quality control related to MOX fuel fabrication in JNC high-lighting the key procedures of quality control in MOX fuel fabrication, measurements of plutonium enriched zone, determination of plutonium concentration, and the advanced method of visual inspection for the surface appearance of the products. The homogeneity of plutonium and uranium is one of key properties from the viewpoint of local heating in reactor operation and dissolubility in reprocessing. Thus plutonium enriched zone (Pu spot) should be detected with an adequate method. The alpha autoradiography has been used to identify the characteristics of the zone. The procedure of alpha autoradiography is established and is successfully applied to the MOX fabrication process. The determination of plutonium concentration is also one of key properties for quality control. JNC has gained the experience relating to Titration, Coulometry, and Isotope Dilution Mass Spectrometry (IDMS) which are known as determination method. IDMS has been used for the determination of plutonium concentration in MOX fabricated in JNC. The advanced method for the visual inspection of the surface appearance of the product. has been developed and demonstrated. The method utilizing the VTR is considered to be well harmonized with fully automated MOX fuel fabrication process. (author)

  12. An electrochemical biosensor for rapid detection of E. coli O157:H7 with highly efficient bi-functional glucose oxidase-polydopamine nanocomposites and Prussian blue modified screen-printed interdigitated electrodes.

    Science.gov (United States)

    Xu, Meng; Wang, Ronghui; Li, Yanbin

    2016-09-21

    The presence of pathogenic bacteria in foods has always been a great threat to the wellbeing of people and the revenue of food manufacturers. Therefore, the demand for advanced detection methods that can sensitively and rapidly detect these pathogens has been of great importance. This study reports an electrochemical biosensor for rapid detection of E. coli O157:H7 with the integration of bifunctional glucose oxidase (GOx)-polydopamine (PDA) based polymeric nanocomposites (PMNCs) and Prussian blue (PB) modified screen-printed interdigitated microelectrodes (SP-IDMEs). The core-shell magnetic beads (MBs)-GOx@PDA PMNCs were first synthesized by the self-polymerization of dopamine (DA). Gold nanoparticles (AuNPs) were dispersed on the surface of PMNCs through biochemical synthesis to achieve further highly efficient adsorption of antibodies (ABs) and GOx. The final product ABs/GOxext/AuNPs/MBs-GOx@PDA PMNCs served as the carrier to separate target bacteria from food matrices as well as the amplifier for electrochemical measurement. The unbound PMNCs were separated by a filtration step and transferred into glucose solution to allow the enzymatic reaction to occur. The change of the current response was measured with an electrochemical detector using PB-modified SP-IDMEs. The constructed biosensor has been proven to be able to detect E. coli O157:H7 with the detection limit of 10(2) cfu ml(-1). The bifunctional PMNCs contain a high load of enzyme and can optimally utilize the binding sites on bacterial cells, which efficiently amplify the signals for measurement. The biosensor in this study exhibited good specificity, reproducibility, and stability and is expected to have a great impact on applications in the detection of foodborne pathogens. PMID:27358917

  13. Optimal distributed computing resources for mask synthesis and tape-out in production environment: an economic analysis

    Science.gov (United States)

    Cork, Chris; Chacko, Manoj; Levi, Shimon

    2005-11-01

    At the deep Subwavelength process nodes, the use of the aggressive optical proximity correction (OPC) and resolution enhancement techniques (RET) is fostering an exponential increase in output database size causing the CPU time required for mask tape-out to increase significantly. This sets up challenging scenarios for integrated device manufacturers (IDMs), and Foundries. For integrated device manufacturers (IDMs), this can impact the time-to-market for their products where even a few days delay could have a huge commercial impact and loss of market window opportunity. For foundries, a shorter turnaround time provides a competitive advantage in their demanding market, too slow could mean customers looking elsewhere for these services; while a fast turnaround may even command a higher price. With FAB turnaround for a CMOS process around 20-30 days, a delay of several days in mask tapeout would contribute a significant fraction to the total time to deliver prototypes. Unlike silicon processing, masks tape-out time can be decreased by applying a combination of extra computing resources and enhancements in the OPC tool like Fracture Friendly OPC (FFOPC) . Mask tape-out groups are taking advantage of the ever-decreasing hardware cost and increasing power of commodity processors. The significant distributability inherent in some commercial Mask Synthesis software can be leveraged to address this critical business issue. Different implementations have different fractions of the code that cannot be parallelized and this affects the efficiency with which it scales, as is described by Amdahl's law. Very few are efficient enough to allow the effective use of 100's of processors, enabling run times to drop from days to only minutes. What follows is a cost aware methodology to quantify the scalability of this class of software, and thus act as a guide to estimating the optimal investment in terms of hardware and software licenses.

  14. Poker Face of Inelastic Dark Matter: Prospects at Upcoming Direct Detection Experiments

    Energy Technology Data Exchange (ETDEWEB)

    Alves, Daniele S.M.; Lisanti, Mariangela; /SLAC /Stanford U., Phys. Dept.; Wacker, Jay G.; /SLAC

    2011-08-12

    The XENON100 and CRESST experiments will directly test the inelastic dark matter explanation for DAMA's 8.9{sigma} anomaly. This article discusses how predictions for direct detection experiments depend on uncertainties in quenching factor measurements, the dark matter interaction with the Standard Model and the halo velocity distribution. When these uncertainties are accounted for, an order of magnitude variation is found in the number of expected events at CRESST and XENON100. The process of testing the DAMA anomaly highlights many of the challenges inherent to direct detection experiments. In addition to determining the properties of the unknown dark matter particle, direct detection experiments must also consider the unknown flux of the incident dark matter, as well as uncertainties in converting a signal from one target nucleus to another. The predictions for both the CRESST 2009 run and XENON100 2010 run show an order of magnitude uncertainty. The nuclear form factor for {sup 184}W, when combined with additional theoretical and experimental uncertainties, will likely prevent CRESST from refuting the iDM hypothesis with an exposure of {Omicron}(100 kg-d) in a model-independent manner. XENON100, on the other hand, will be able to make a definitive statement about a spin-independent, inelastically scattering dark matter candidate. Still, the CRESST 2009 data can potentially confirm iDM for a large range of parameter space. In case of a positive signal, the combined data from CRESST and XENON100 will start probing the properties of the Milky Way DM profile and the interaction of the SM with the dark matter.

  15. Rapid detection of Escherichia coli O157:H7 and Salmonella Typhimurium in foods using an electrochemical immunosensor based on screen-printed interdigitated microelectrode and immunomagnetic separation.

    Science.gov (United States)

    Xu, Meng; Wang, Ronghui; Li, Yanbin

    2016-02-01

    Foodborne pathogens have continuously been a serious food safety issue and there is a growing demand for a rapid and sensitive method to screen the pathogens for on-line or in-field applications. Therefore, an impedimetric immunosensor based on the use of magnetic beads (MBs) for separation and a screen-printed interdigitated microelectrode (SP-IDME) for measurement was studied for the rapid detection of Escherichia coli O157:H7 and Salmonella Typhimurium in foods. Streptavidin coated MBs were functionalized with corresponding biotinylated antibodies (Ab) to capture the target bacteria. The glucose oxidase (GOx)-Ab conjugates were employed to label the MBs-Ab-cell complexes. The yielded MBs-Ab-cell-Ab-GOx biomass was mixed with the glucose solution to trigger an enzymatic reaction which produced gluconic acid. This increased the ion strength of the solution, thus decreasing the impedance of the solution measured on the SP-IDME. Our results showed that the immunosensor was capable of specifically detecting E. coli O157:H7 and S. Typhimurium within the range of 10(2)-10(6) cfu ml(-1) in the pure culture samples. E. coli O157:H7 in ground beef and S. Typhimurium in chicken rinse water were also examined. The limits of detection (LODs) for the two bacteria in foods were 2.05×10(3) cfu g(-1) and 1.04×10(3) cfu ml(-1), respectively. This immunosensor required only a bare electrode to measure the impedance changes, and no surficial modification on the electrode was needed. It was low-cost, reproducible, easy-to-operate, and easy-to-preserve. All these merits demonstrated this immunosensor has great potential for the rapid and on-site detection of pathogenic bacteria in foods. PMID:26653441

  16. A virtual environment for modeling and testing sensemaking with multisensor information

    Science.gov (United States)

    Nicholson, Denise; Bartlett, Kathleen; Hoppenfeld, Robert; Nolan, Margaret; Schatz, Sae

    2014-05-01

    Given today's challenging Irregular Warfare, members of small infantry units must be able to function as highly sensitized perceivers throughout large operational areas. Improved Situation Awareness (SA) in rapidly changing fields of operation may also save lives of law enforcement personnel and first responders. Critical competencies for these individuals include sociocultural sensemaking, the ability to assess a situation through the perception of essential salient environmental and behavioral cues, and intuitive sensemaking, which allows experts to act with the utmost agility. Intuitive sensemaking and intuitive decision making (IDM), which involve processing information at a subconscious level, have been cited as playing a critical role in saving lives and enabling mission success. This paper discusses the development of a virtual environment for modeling, analysis and human-in-the-loop testing of perception, sensemaking, intuitive sensemaking, decision making (DM), and IDM performance, using state-of-the-art scene simulation and modeled imagery from multi-source systems, under the "Intuition and Implicit Learning" Basic Research Challenge (I2BRC) sponsored by the Office of Naval Research (ONR). We present results from our human systems engineering approach including 1) development of requirements and test metrics for individual and integrated system components, 2) the system architecture design 3) images of the prototype virtual environment testing system and 4) a discussion of the system's current and future testing capabilities. In particular, we examine an Enhanced Interaction Suite testbed to model, test, and analyze the impact of advances in sensor spatial, and temporal resolution to a user's intuitive sensemaking and decision making capabilities.

  17. Development of an accurate, sensitive, and robust isotope dilution laser ablation ICP-MS method for simultaneous multi-element analysis (chlorine, sulfur, and heavy metals) in coal samples

    International Nuclear Information System (INIS)

    A method for the direct multi-element determination of Cl, S, Hg, Pb, Cd, U, Br, Cr, Cu, Fe, and Zn in powdered coal samples has been developed by applying inductively coupled plasma isotope dilution mass spectrometry (ICP-IDMS) with laser-assisted introduction into the plasma. A sector-field ICP-MS with a mass resolution of 4,000 and a high-ablation rate laser ablation system provided significantly better sensitivity, detection limits, and accuracy compared to a conventional laser ablation system coupled with a quadrupole ICP-MS. The sensitivity ranges from about 590 cps for 35Cl+ to more than 6 x 105 cps for 238U+ for 1 μg of trace element per gram of coal sample. Detection limits vary from 450 ng g-1 for chlorine and 18 ng g-1 for sulfur to 9.5 pg g-1 for mercury and 0.3 pg g-1 for uranium. Analyses of minor and trace elements in four certified reference materials (BCR-180 Gas Coal, BCR-331 Steam Coal, SRM 1632c Trace Elements in Coal, SRM 1635 Trace Elements in Coal) yielded good agreement of usually not more than 5% deviation from the certified values and precisions of less than 10% relative standard deviation for most elements. Higher relative standard deviations were found for particular elements such as Hg and Cd caused by inhomogeneities due to associations of these elements within micro-inclusions in coal which was demonstrated for Hg in SRM 1635, SRM 1632c, and another standard reference material (SRM 2682b, Sulfur and Mercury in Coal). The developed LA-ICP-IDMS method with its simple sample pretreatment opens the possibility for accurate, fast, and highly sensitive determinations of environmentally critical contaminants in coal as well as of trace impurities in similar sample materials like graphite powder and activated charcoal on a routine basis. (orig.)

  18. Dark matter direct detection with non-Maxwellian velocity structure

    International Nuclear Information System (INIS)

    The velocity distribution function of dark matter particles is expected to show significant departures from a Maxwell-Boltzmann distribution. This can have profound effects on the predicted dark matter - nucleon scattering rates in direct detection experiments, especially for dark matter models in which the scattering is sensitive to the high velocity tail of the distribution, such as inelastic dark matter (iDM) or light (few GeV) dark matter (LDM), and for experiments that require high energy recoil events, such as many directionally sensitive experiments. Here we determine the velocity distribution functions from two of the highest resolution numerical simulations of Galactic dark matter structure (Via Lactea II and GHALO), and study the effects for these scenarios. For directional detection, we find that the observed departures from Maxwell-Boltzmann increase the contrast of the signal and change the typical direction of incoming DM particles. For iDM, the expected signals at direct detection experiments are changed dramatically: the annual modulation can be enhanced by more than a factor two, and the relative rates of DAMA compared to CDMS can change by an order of magnitude, while those compared to CRESST can change by a factor of two. The spectrum of the signal can also change dramatically, with many features arising due to substructure. For LDM the spectral effects are smaller, but changes do arise that improve the compatibility with existing experiments. We find that the phase of the modulation can depend upon energy, which would help discriminate against background should it be found

  19. Precise and accurate determination of plutonium by controlled-potential coulometry and its uncertainty evaluation

    International Nuclear Information System (INIS)

    Precise and accurate analysis of plutonium is necessary for material control and safeguards in nuclear facilities. In this study, controlled-potential coulometry, which yields absolute results and high precision, was applied to the determination of plutonium for achieving the highest level of accuracy. The measurement cell and electrodes of our coulometry system were optimized following ISO12183:2005, and the calibration of the coulometer was performed using NIST (National Institute of Standards and Technology, U.S.) certified equipments. The influences of fluoride which was used to dissolve a Pu metal and of nitrite which arise from the decomposition of nitrate were eliminated by adding sulfuric acid and amidosulfuric acid to the sample. Also, hydrogen peroxide was added to the sample to reduce Pu(VI) to Pu(IV). A plutonium sample prepared from a Pu metal (NBL CRM126) was measured according to the procedure optimized in this study. As a result, the measured value agreed well with the certified value. The relative standard deviation was 0.05% (n=17). For spike preparation of isotope dilution mass spectrometry (IDMS), a plutonium solution was prepared from MOX powder stored in Japan Atomic Energy Agency. The plutonium content in the prepared solution was characterized by coulometry. As a result, the plutonium concentration of 15.5995 mgPu/g was obtained. The uncertainty was calculated following the ISO/BIPM Guide to the Expression of Uncertainties in Measurements. The expanded uncertainty was ±0.0036 mgPu/g with confidence interval of 95%. The results obtained by coulometry were also in good agreement with those obtained by IDMS. Thus the proposed coulometry method was successfully applied for the determination of plutonium at the highest level of precision and accuracy. (author)

  20. Extending i-line capabilities through variance characterization and tool enhancement

    Science.gov (United States)

    Miller, Dan; Salinas, Adrian; Peterson, Joel; Vickers, David; Williams, Dan

    2006-03-01

    Continuous economic pressures have moved a large percent of integrated device manufacturing (IDM) operations either overseas or to foundry operations over the last 10 years. These pressures have left the IDM fabs in the U.S. with required COO improvements in order to maintain operations domestically. While the assets of many of these factories are at a very favorable point in the depreciation life cycle, the equipment and processes are constrained to the quality of the equipment in its original state and the degradation over its installed life. With the objective to enhance output and improve process performance, this factory and their primary lithography process tool supplier have been able to extend the usable life of the existing process tools, increase the output of the tool base, and improve the distribution of the CDs on the product produced. Texas Instruments Incorporated lead an investigation with the POLARIS ® Systems & Services business of FSI International to determine the sources of variance in the i-line processing of a wide array of IC device types. Data from the sources of variance were investigated such as PEB temp, PEB delay time, develop recipe, develop time, and develop programming. While PEB processes are a primary driver of acid catalyzed resists, the develop mode is shown in this work to have an overwhelming impact on the wafer to wafer and across wafer CD performance of these i-line processes. These changes have been able to improve the wafer to wafer CD distribution by more than 80 %, and the within wafer CD distribution by more than 50 % while enabling a greater than 50 % increase in lithography cluster throughput. The paper will discuss the contribution from each of the sources of variance and their importance in overall system performance.

  1. Development of a candidate certified reference material of cypermethrin in green tea

    International Nuclear Information System (INIS)

    Highlights: ► A cypermethrin CRM in green tea was developed. ► Using two isotope dilution mass spectrometry techniques for characterization. ► Certified value of 148 μg kg−1 with expanded uncertainty of ±9.2%. ► Support quality assurance of pesticide residue analysis in tea to testing. - Abstract: This paper presents the preparation of a candidate certified reference material (CRM) of cypermethrin in green tea, GLHK-11-01a according to the requirements of ISO Guide 34 and 35. Certification of the material was performed using a newly developed isotope dilution mass spectrometry (IDMS) approach, with gas chromatography high resolution mass spectrometry (GC–HRMS) and gas chromatography–tandem mass spectrometry (GC–MS/MS). Statistical analysis (one-way ANOVA) showed excellent agreement of the analytical data sets generated from the two mass spectrometric detections. The characterization methods have also been satisfactorily applied in an Asia-Pacific Metrology Program (APMP) interlaboratory comparison study. Both the GC–HRIDMS and GC–IDMS/MS methods proved to be sufficiently reliable and accurate for certification purpose. The certified value of cypermethrin in dry mass fraction was 148 μg kg−1 and the associated expanded uncertainty was 14 μg kg−1. The uncertainty budget was evaluated from sample in homogeneity, long-term and short-term stability and variability in the characterization procedure. GLHK-11-01a is primarily developed to support the local and wider testing community on need basis in quality assurance work and in seeking accreditation.

  2. [Mental disease in two classical music composers].

    Science.gov (United States)

    Rempelakos, L; Poulakou-Rebelakou, E; Ploumpidis, D

    2012-01-01

    A study οn two neglected classical music composers suffering a not syphilitic mental disease, is attempted here, syphilis of the central nervous system being frequent in that time. A brief overview on the psychiatric ailments of many great composers reveals suicide attempts and more or less severe depression following external events. The issue of a possible relationship between mental disease and (musical) creativity can be discussed, as mood swings and a certain tendency to melancholia are frequent features of a talented brain (a fact that can also be detected in their works). The first case presented here is Hans Rott from Austria, the beloved student of Anton Bruckner, who was considered to be at least equal to his famous classmate Gustav Mahler. The great expectations of his teacher and his friends suddenly came to an end, when he suffered a crisis of schizophrenia and was hospitalized in an insane asylum in Lower Austria. The tragic psychiatric adventure of the young musician lasted almost four years. He was diagnosed as a case of "hallucinatory insanity" and "persecution mania" by the medical staff, before dying of tuberculosis, aged only 26, and having completed only one symphony and several smaller works. His name came again on surface only a century after his death, when in 1989 his Symphony in E Major was discovered and premiered with great success, permitting to its creator a posthumous recognition, among Bruckner and Mahler. The second case of mental illness is that of the Armenian Komitas Vardapet. He was an orphan who grew up in theological schools and became a monk and later a priest, though he spent some years in Berlin in order to develop his musical skills. He is considered to be an authority of Armenian ecclesiastic music, introducing polyphony in the Armenian Church's music and collecting numerous traditional songs from all parts of Armenia. In 1915, during the Armenian genocide he was deported, tortured but finally saved, due to interventions

  3. Métamorphoses de l’intrigue musicale (XIXe-XXe siècles Metamorphoses of Musical Plot (18th-20th Centuries

    Directory of Open Access Journals (Sweden)

    Márta Grabócz

    2012-01-01

    Full Text Available L’auteur définit d’abord le cadre narratologique, celui de la narratologie classique, dans le but d’explorer la narrativité en musique. Elle fournit six types de définition en fonction de leur pertinence dans l’analyse musicale. Dans le but de créer une possible correspondance entre la séquence narrative et les sections d’une œuvre musicale, l’auteur introduit la notion de « signification musicale » et ses termes utilisés en musicologie (« topiques » ou « intonations ». Concernant leur mode d’organisation dans une forme musicale, quelques modèles sémiotiques ou narratologiques sont évoqués. Le IIIe chapitre offre les définitions « classiques » de l’intrigue, suivies de deux exemples musicaux : une sonate de Kuhnau (1700 et un mouvement lent d’une symphonie de Mozart (Andante de K. 504 dite de « Prague ». La IVe partie de l’article introduit les définitions « post-classiques » de l’intrigue, en les illustrant avec un exemple de Beethoven (Ouverture Leonore N° 3, op.72A, pour illustrer le suspense et la Vallée d’Obermann de Liszt (pour illustrer le cas d’intrigue appelé « curiosité »..The author defines at first the narratological frame, that of classical narratology, in the aim to explore musical narrativity. She provides six types of definition according to their pertinence in musical analysis. In order to create a possible correspondence between the narrative sequence and the sections of a musical piece, the author introduces the notion of “musical signification” and their terms used in musicology : the category of “topic” and that of “intonation”. As to their modes of organization within a musical form, some semiotic and narrative models are mentioned, those used by different musicologists. The part III provides “classical” definitions of the plot, followed by two musical examples (a “Biblical sonata” by Kuhnau from 1700 and the Andante of the symphony K.504 of Mozart

  4. Bringing Astronomy Directly to People Who Do Not Come to Star Parties, Science Museums, or Science Festivals

    Science.gov (United States)

    Lubowich, Donald A.

    2013-01-01

    My successful programs have included telescope observations, hands-on activities, and edible astronomy demonstrations for: outdoor concerts or music festivals; the National Mall; churches, synagogues, seminaries, or clergy conferences; the Ronald McDonald House of Long Island (New Hyde Park, NY), the Winthrop University Hospital Children’s Medical Center (Mineola, NY); the Fresh Air Fund summer camps; a Halloween star party with costumed kids looking through telescopes; a Super Bowl Star Party; the World Science Festival (NYC); the Princeton University Science and Engineering Expo; the USA Science and Engineering Festival; and the NYC Columbus Day Parade. These outreach activities have reached thousands of people including many young girls. Information was also provided about local science museums, citizen science projects, astronomy educational sites, and astronomy clubs to encourage learning after these events. In 2010 I created Astronomy Night on the National Mall (co-sponsored the White House Office of Science and Technology Policy) with the participation of astronomy clubs, Chandra X-Ray Center, STScI, NASA, NOAO, NSF and the National Air and Space Museum. Since 2009 my NASA-funded Music and Astronomy Under the Stars (MAUS) program has brought astronomy to 50,000 music lovers who attended the Central Park Jazz, Newport Folk, Tanglewood, or Ravinia music festivals or classical, folk, rock, pop, opera, or county-western concerts in local parks assisted by astronomy clubs. MAUS is an evening, nighttime, and cloudy weather traveling astronomy program combining solar, optical, and radio telescope observations; a live image projection system; large outdoor posters and banners; videos; and hands-on activities before and after the concerts or at intermission. Yo-Yo-Ma and the Chicago Symphony or Boston Symphony Orchestras, the McCoy Tyner Quartet with Ravi Coltrane, Esperanza Spalding, the Stanley Clarke Band, Phish, Blood Sweat and Tears, Deep Purple, Patti Smith

  5. Sustainable agriculture. Practice in progress; Duurzame landbouw. De praktijk onderweg

    Energy Technology Data Exchange (ETDEWEB)

    Cino, B.J.

    2004-07-01

    In the booklet 'Een routekaart naar duurzame landbouw: wegen en kruispunten' (A roadmap to sustainable agriculture: roads and crossings) a line of thought is elaborated which could guide the quest for sustainable agriculture. The present study is meant to test this line of thought for its practical use. Starting-point was the idea that practitioners have already started their own quest for sustainable agriculture and that their experiences would offer food for thought. Two cases have been studied, the environmental co-operatives VEL and VANLA and the Innovatieplatform Duurzame Meierij (IDM, platform for a sustainable Meierij). In the aforementioned roadmap five dimensions are identified: why, what, where, how much and how. The present study has focused on the 'how': how do practitioners strive for sustainable agriculture. VEL and VANLA strive for a more environmentally friendly dairy farming that actively integrates nature conservation and landscape management. Ecological and economical sustainability should go hand in hand and the relationship with the other stakeholders in the area is thought to be important. Obstacles in the quest for sustainability, according to VEL and VANLA, are mainly found at the level of policy and its implementation, in the present knowledge system and in the remuneration for sustainable farm management. The IDM strives for a sustainable Meierij (Duurzame Meierij), with a focus on the rural areas. The platform checks projects using a model developed by Telos (Brabants Centre for Sustainability Issues) and in which three forms of capital are central: ecological, social-cultural and economical. Obstacles in the quest for sustainability, according to IDM, are mainly found at the level of policy and its implementation, in the price setting for sustainable products and in the perception and attitude regarding sustainability amongst urbanites, consumers and the different stakeholders of the area. Both cases are challenging

  6. Estimating a realistic procedural blank for the determination of Fe in seawater by isotope dilution: a fundamental analytical issue

    International Nuclear Information System (INIS)

    It is well known that direct analysis of seawater by means of inductively coupled plasma mass spectrometry (ICP-MS) is hardly possible because of the salt load in the samples. Determination of the element content at ultra-trace level in open-ocean water requires a separation from the matrix associated to significant concentration factors. For iron, an isotope dilution ICP-MS method was proposed based on a multiple steps protocol, including a co-precipitation with magnesium hydroxide after ammonia loading and consecutive dissolution with hydrochloric acid. To be able to measure the iron content in the low pg g-1 range a correct assessment of the analytical procedural blank is of crucial importance. Not only this blank must be low, but also realistic (i.e. based on the complete analytical sequence applied to real iron free seawater) and reproducible. This is particularly difficult considering the ubiquity of iron and the complexity of the seawater matrix and, despite years of experiments and publications, this remains a fundamental analytical challenge and a great source of complexity for the realisation of reliable profiles of dissolved iron data. The present study considers different approaches we developed to assess, in a realistic way, the procedural blank of the IDMS method proposed by Wu and Boyle. These authors use ∼4%-sample volume for their procedural blank determination, and the results presented are rather convincing. However, down-sizing by a factor of ∼25 the sample volume, which minimizes sample-tube contact and lab ware contribution to the blank, can easily lead to changes in the analytical protocol, and thus to non-realistic procedural blank values. Instead, our investigations aimed at reproducing the full set of experimental steps involved in the determination of iron in seawater by IDMS at the nM level or below. Our results are evaluated in the light of those claimed by Wu and Boyle. The ICP-MS measurements were performed by means of a single

  7. A novel quantification strategy of transferrin and albumin in human serum by species-unspecific isotope dilution laser ablation inductively coupled plasma mass spectrometry (ICP-MS)

    International Nuclear Information System (INIS)

    Highlights: • Species-unspecific ID-PAGE-LA-ICP-MS was used to quantify Alb and Tf in human serum. • Addition methods of species-unspecific 34S spike were evaluated. • Isotope change conditions were investigated to reach satisfactory “isotope equilibration”. • Human serum CRM (ERM-DA470k/IFCC) was used to validate the new arrangements. • The developed method offers potential for accurate quantification of protein by ID-PAGE-LA-ICP-MS. - Abstract: Species-specific (SS) isotope dilution analysis with gel electrophoresis (GE)-laser ablation (LA)-ICP-MS is a promising technique for the quantification of particular metal-binding proteins in biological samples. However, unavailable isotopically enriched spike and metal losses in GE separation are main limitations for SS-isotope dilution PAGE-LA-ICP-MS. In this study, we report for the first time the absolute quantification of transferrin (Tf) and albumin (Alb) in human serum by non-denaturing (native) GE combined with species-unspecific isotope dilution mass spectrometry (IDMS). In order to achieve a homogeneous distribution of both protein and isotope-enriched spike (simulated isotope equilibration), immersing the protein strips with 34S spike solution after gel electrophoresis was demonstrated to be an effective way of spike addition. Furthermore, effects of immersion time and 34S spike concentration were investigated to obtain optimal conditions of the post-electrophoresis isotope dilution method. The relative mass of spike and ablated sample (msp/msam) in IDMS equation was calculated by standard Tf and Alb proteins, which could be applied to the quantification of Tf and Alb in ERM-DA470k/IFCC for method confirmation. The results were in agreement with the certified value with good precision and small uncertainty (1.5–3%). In this method, species-specific spike protein is not necessary and the integrity of the heteroatom-protein could be maintained in sample preparation process. Moreover, the

  8. A radioimmunoassay for erythropoietin: serum levels in normal human subjects and patients with hemopoietic disorders

    Energy Technology Data Exchange (ETDEWEB)

    Rege, A.B.; Brookins, J.; Fisher, J.W.

    1982-12-01

    An RIA for Ep has been developed that is highly sensitive and specific. A homogeneous Ep preparation was labeled with /sup 125/I by the chloramine-T method to a specific activity of 90 to 136 ..mu..Ci/..mu..g and immunoreactivity of 80%. Ep antiserum, which was produced to a human urinary Ep preparation (80 U/mg of protein), was adsorbed with normal human urinary and serum proteins without any loss in sensitivity of the RIA to increase the specificity of the assay. A good correlation was seen between the RIA and the exhypoxic polycythemic mouse assay (corr. coef. 0.967; slope 1.05 and ''y'' intercept 0.75). Ep titers in sera from 175 hematologically normal human subjects exhibited a normal frequency distribution and ranged between 5.8 and 36.6 mU/ml with a mean of 14.9 +/- 4.7 (S.D.) and median of 14.3. Serum Ep titers were markedly elevated in seven patients with aplastic anemia and one patient with pure red cell aplasia (1350 to 20,640 mU/ml) and were lower than normal in two patients with polycythemia vera (8.1 and 9.4 mU/ml). The serum Ep titers in a prenephrectomy patient with chronic glomerulonephritis (31.1 mU/ml) decreased to below normal levels (9.04 mU/ml) after nephrectomy. The cord serum erythropoietin titers in 10 IDM (90.82 +/- 134.1 (S.D.) mu/ml) returned to values within the normal range (13.86 +/- 5.55) on day 3 after birth, suggesting the utility of the RIA in elucidating the role of hypoxia and/or insulin in increased erythropoiesis in IDM. The serum Ep titers in patients with anemias and polycythemias were compared to those of normal human subjects and agreed well with pathophysiologic mechanisms of these hemopoietic disorders, confirming the validity of the RIA.

  9. A radioimmunoassay for erythropoietin: serum levels in normal human subjects and patients with hemopoietic disorders

    Energy Technology Data Exchange (ETDEWEB)

    Rege, A.B.; Brookins, J.; Fisher, J.W.

    1982-12-01

    An RIA for Ep has been developed that is highly sensitive and specific. A homogeneous Ep preparation was labeled with /sup 125/I by the chloramine-T method to a specific activity of 90 to 136 micro Ci/microgram and immunoreactivity of 80%. Ep antiserum, which was produced to a human urinary Ep preparation (80 U/mg of protein), was adsorbed with normal human urinary and serum proteins without any loss in sensitivity of the RIA to increase the specificity of the assay. A good correlation was seen between the RIA and the exhypoxic polycythemic mouse assay (corr. coef. 0.967; slope 1.05 and y intercept 0.75). Ep titers in sera from 175 hematologically normal human subjects exhibited a normal frequency distribution and ranged between 5.8 and 36.6 mU/ml with a mean of 14.9 +/- 4.7 (S.D.) and median of 14.3 Serum Ep titers were markedly elevated in seven patients with aplastic anemia and one patient with pure red cell aplasia (1350 to 20,640 mU/ml) and were lower than normal in two patients with polycythemia vera (8.1 and 9.4 mU/ml). The serum Ep titers in a prenephrectomy patient with chronic glomerulonephritis (32.1 mU/ml) decreased to below normal levels (9.04 mU/ml) after nephrectomy. The cord serum erythropoietin titers in 10 IDM (90.82 +/- 134.1 (S.D.) mu/ml) returned to values within the normal range (13.86 +/- 5.55) on day 3 after birth, suggesting the utility of the RIA in elucidating the role of hypoxia and/or insulin in increased erythropoiesis in IDM. The serum Ep titers in patients with anemias and polycythemias were compared to those of normal human subjects and agreed well with pathophysiologic mechanisms of these hemopoietic disorders, confirming the validity of the RIA.

  10. Development of an accurate, sensitive, and robust isotope dilution laser ablation ICP-MS method for simultaneous multi-element analysis (chlorine, sulfur, and heavy metals) in coal samples

    Energy Technology Data Exchange (ETDEWEB)

    Boulyga, Sergei F. [University of Natural Resources and Applied Life Sciences, Department of Chemistry, Division of Analytical Chemistry-VIRIS Laboratory, Vienna (Austria); Johannes Gutenberg-University, Institute of Inorganic Chemistry and Analytical Chemistry, Mainz (Germany); Heilmann, Jens; Heumann, Klaus G. [Johannes Gutenberg-University, Institute of Inorganic Chemistry and Analytical Chemistry, Mainz (Germany); Prohaska, Thomas [University of Natural Resources and Applied Life Sciences, Department of Chemistry, Division of Analytical Chemistry-VIRIS Laboratory, Vienna (Austria)

    2007-10-15

    A method for the direct multi-element determination of Cl, S, Hg, Pb, Cd, U, Br, Cr, Cu, Fe, and Zn in powdered coal samples has been developed by applying inductively coupled plasma isotope dilution mass spectrometry (ICP-IDMS) with laser-assisted introduction into the plasma. A sector-field ICP-MS with a mass resolution of 4,000 and a high-ablation rate laser ablation system provided significantly better sensitivity, detection limits, and accuracy compared to a conventional laser ablation system coupled with a quadrupole ICP-MS. The sensitivity ranges from about 590 cps for {sup 35}Cl{sup +} to more than 6 x 10{sup 5} cps for {sup 238}U{sup +} for 1 {mu}g of trace element per gram of coal sample. Detection limits vary from 450 ng g{sup -1} for chlorine and 18 ng g{sup -1} for sulfur to 9.5 pg g{sup -1} for mercury and 0.3 pg g{sup -1} for uranium. Analyses of minor and trace elements in four certified reference materials (BCR-180 Gas Coal, BCR-331 Steam Coal, SRM 1632c Trace Elements in Coal, SRM 1635 Trace Elements in Coal) yielded good agreement of usually not more than 5% deviation from the certified values and precisions of less than 10% relative standard deviation for most elements. Higher relative standard deviations were found for particular elements such as Hg and Cd caused by inhomogeneities due to associations of these elements within micro-inclusions in coal which was demonstrated for Hg in SRM 1635, SRM 1632c, and another standard reference material (SRM 2682b, Sulfur and Mercury in Coal). The developed LA-ICP-IDMS method with its simple sample pretreatment opens the possibility for accurate, fast, and highly sensitive determinations of environmentally critical contaminants in coal as well as of trace impurities in similar sample materials like graphite powder and activated charcoal on a routine basis. (orig.)

  11. Evaluation of the combined measurement uncertainty in isotope dilution by MC-ICP-MS

    Energy Technology Data Exchange (ETDEWEB)

    Fortunato, G.; Wunderli, S. [Metrology in Chemistry, Swiss Federal Laboratories for Materials Testing and Research (EMPA), Lerchenfeldstrasse 5, 9014 St. Gallen (Switzerland)

    2003-09-01

    The combination of metrological weighing, the measurement of isotope amount ratios by a multicollector inductively coupled plasma mass spectrometer (MC-ICP-MS) and the use of high-purity reference materials are the cornerstones to achieve improved results for the amount content of lead in wine by the reversed isotope dilution technique. Isotope dilution mass spectrometry (IDMS) and reversed IDMS have the potential to be a so-called primary method, with which close comparability and well-stated combined measurement uncertainties can be obtained. This work describes the detailed uncertainty budget determination using the ISO-GUM approach. The traces of lead in wine were separated from the matrix by ion exchange chromatography after HNO{sub 3}/H{sub 2}O{sub 2} microwave digestion. The thallium isotope amount ratio (n({sup 205}Tl)/n({sup 203}Tl)) was used to correct for mass discrimination using an exponential model approach. The corrected lead isotope amount ratio n({sup 206}Pb)/n({sup 208}Pb) for the isotopic standard SRM 981 measured in our laboratory was compared with ratio values considered to be the least uncertain. The result has been compared in a so-called pilot study ''lead in wine'' organised by the CCQM (Comite Consultatif pour la Quantite de Matiere, BIPM, Paris; the highest measurement authority for analytical chemical measurements). The result for the lead amount content k(Pb) and the corresponding expanded uncertainty U given by our laboratory was:k(Pb)=1.329 x 10-10mol g-1 (amount content of lead in wine)U[k(Pb)]=1.0 x 10-12mol g-1 (expanded uncertainty U=k x uc, k=2) The uncertainty of the main influence parameter of the combined measurement uncertainty was determined to be the isotope amount ratio R{sub 206,B} of the blend between the enriched spike and the sample. (orig.)

  12. Simultaneous multi-species determination of trimethyllead, monomethylmercury and three butyltin compounds by species-specific isotope dilution GC-ICP-MS in biological samples.

    Science.gov (United States)

    Poperechna, Nataliya; Heumann, Klaus G

    2005-09-01

    An accurate and sensitive multi-species species-specific isotope dilution GC-ICP-MS method was developed for the simultaneous determination of trimethyllead (Me3Pb+), monomethylmercury (MeHg+) and the three butyltin species Bu3Sn+, Bu2Sn2+, and BuSn3+ in biological samples. The method was validated by three biological reference materials (CRM 477, mussel tissue certified for butyltins; CRM 463, tuna fish certified for MeHg+; DORM 2, dogfish muscle certified for MeHg+). Under certain conditions, and with minor modifications of the sample pretreatment procedure, this method could also be transferred to environmental samples such as sediments, as demonstrated by analyzing sediment reference material BCR 646 (freshwater sediment, certified for butyltins). The detection limits of the multi-species GC-ICP-IDMS method for biological samples were 1.4 ng g(-1) for MeHg+, 0.06 ng g(-1) for Me3Pb+, 0.3 ng g(-1) for BuSn3+ and Bu3Sn+, and 1.2 ng g(-1) for Bu2Sn2+. Because of the high relevance of these heavy metal alkyl species to the quality assurance of seafood, the method was also applied to corresponding samples purchased from a supermarket. The methylated lead fraction in these samples, correlated to total lead, varied over a broad range (from 0.01% to 7.6%). On the other hand, the MeHg+ fraction was much higher, normally in the range of 80-100%. Considering that we may expect tighter legislative limitations on MeHg+ levels in seafood in the future, we found the highest methylmercury contents (up to 10.6 microg g(-1)) in two shark samples, an animal which is at the end of the marine food chain, whereas MeHg+ contents of less than 0.2 microg g(-1) were found in most other seafood samples; these results correlate with the idea that MeHg+ is usually of biological origin in the marine environment. The concentration of butyltins and the fraction of the total tin content that is from butyltins strongly depend on possible contamination, due to the exclusively anthropogenic

  13. T2 mapping in patellar chondromalacia

    Energy Technology Data Exchange (ETDEWEB)

    Ruiz Santiago, Fernando, E-mail: ferusan12@gmail.com [Department of Radiology, Traumatology Hospital, University Hospital Virgen de las Nieves, Granada (Spain); Pozuelo Calvo, Rocío [Department of Rehabilitation and Physical therapy, Traumatology Hospital, University Hospital Virgen de las Nieves, Granada (Spain); Almansa López, Julio [Department of Physic, University Hospital Virgen de las Nieves, Granada (Spain); Guzmán Álvarez, Luis; Castellano García, María del Mar [Department of Radiology, Traumatology Hospital, University Hospital Virgen de las Nieves, Granada (Spain)

    2014-06-15

    Objective: To study the correlation between the T2 relaxation times of the patellar cartilage and morphological MRI findings of chondromalacia. Methods: This prospective study comprises 50 patients, 27 men and 23 women suffering of anterior knee pain (mean age: 29.7, SD 8.3 years; range: 16–45 years). MRI of 97 knees were performed in these patients at 1.5 T magnet including sagittal T1, coronal intermediate, axial intermediate fat sat and T2 mapping. Chondromalacia was assessed using a modified version of Noyes classification. The relaxation time, T2, was studied segmenting the full thickness of the patellar cartilage in 12 areas: 4 proximal (external facet–proximal–lateral (EPL), external facet–proximal–central (EPC), internal facet–proximal–central (IPC), internal facet–proximal–medial (IPM), 4 in the middle section (external facet–middle–lateral (EML), external facet–middle–central (EMC), internal facet–middle–central (IMC), internal facet–middle–medial (IMM) and 4 distal (external facet–distal–lateral (EDL), external facet–distal–central (EDC), internal facet–distal–central (IDC), internal facet–distal–medial (IDM). Results: T2 values showed a significant increase in mild chondromalacia regarding normal cartilage in most of the cartilage areas (p < 0.05), except in the internal distal facet (IDC and IDM), EPC, EDL, and IMM. Severe chondromalacia was characterized by a fall of T2 relaxation times with loss of statistical significant differences in comparison with normal cartilage, except in EMC and IMC, where similar values as mild chondromalacia were maintained (p < 0.05). Conclusions: Steepest increase in T2 values of patellar cartilage occurs in early stages of patellar cartilage degeneration. Progression of morphologic changes of chondromalacia to more severe degrees is associated to a new drop of T2 relaxation times approaching basal values in most of the areas of the patellar cartilage, except in the

  14. Isotope dilution quantification of ultratrace gamma-glutamyl-Se-methylselenocysteine species using HPLC with enhanced ICP-MS detection by ultrasonic nebulisation or carbon-loaded plasma.

    Science.gov (United States)

    Goenaga Infante, Heidi; Ovejero Bendito, María del Carmen; Cámara, Carmen; Evans, Linda; Hearn, Ruth; Moesgaard, Sven

    2008-04-01

    A method for the accurate determination of ultratrace selenium species of relevance to cancer research, such as gamma-glutamyl-Se-methylselenocysteine (gamma-glutamyl-SeMC), using species-specific double isotope dilution analysis (IDA) with HPLC-ICP-MS is reported for the first time. The (77)Se-enriched gamma-glutamyl-SeMC spike was produced in-house by collecting the fraction at the retention time of the gamma-glutamyl-SeMC peak from a chromatographed aqueous extract of (77)Se-enriched yeast, pooling the collected fractions and freeze-drying the homogenate. The Se content of this spike was characterised using reverse isotope dilution mass spectrometry (IDMS) and the isotopic composition of this spike was checked prior to quantification of the natural abundance dipeptide species in garlic using speciated IDA. The extraction of the gamma-glutamyl-SeMC species in water was performed in a sonication bath for 2 h after adding an appropriate quantity of (77)Se-enriched gamma-glutamyl-SeMC to 50 mg of garlic to give optimal (78)Se/(77)Se and (82)Se/(77)Se ratios of 1.5 and 0.6, respectively. The effect of ultrasonic nebulisation, in comparison with the loading of the ICP with carbon (through the addition of methane gas on-line), on the detection of Se associated with gamma-glutamyl-SeMC using collision/reaction cell ICP-MS with hydrogen as collision gas was investigated. Sensitivity enhancements of approximately fourfold and twofold were achieved using USN and methane mixed plasma, respectively, in comparison with conventional nebulisation and conventional Ar ICP-MS. However, an approximately twofold improvement in the detection limit was achieved using both approaches (42 ng kg(-1) for (78)Se using peak height measurements). The use of species-specific IDMS enabled quantification of the dipeptide species at ng g(-1) levels (603 ng g(-1) Se) in the complex food matrix with a relative standard deviation (RSD, n = 4) of 4.5%, which was approximately half that obtained

  15. A novel quantification strategy of transferrin and albumin in human serum by species-unspecific isotope dilution laser ablation inductively coupled plasma mass spectrometry (ICP-MS)

    Energy Technology Data Exchange (ETDEWEB)

    Feng, Liuxing, E-mail: fenglx@nim.ac.cn; Zhang, Dan; Wang, Jun; Shen, Dairui; Li, Hongmei

    2015-07-16

    Highlights: • Species-unspecific ID-PAGE-LA-ICP-MS was used to quantify Alb and Tf in human serum. • Addition methods of species-unspecific {sup 34}S spike were evaluated. • Isotope change conditions were investigated to reach satisfactory “isotope equilibration”. • Human serum CRM (ERM-DA470k/IFCC) was used to validate the new arrangements. • The developed method offers potential for accurate quantification of protein by ID-PAGE-LA-ICP-MS. - Abstract: Species-specific (SS) isotope dilution analysis with gel electrophoresis (GE)-laser ablation (LA)-ICP-MS is a promising technique for the quantification of particular metal-binding proteins in biological samples. However, unavailable isotopically enriched spike and metal losses in GE separation are main limitations for SS-isotope dilution PAGE-LA-ICP-MS. In this study, we report for the first time the absolute quantification of transferrin (Tf) and albumin (Alb) in human serum by non-denaturing (native) GE combined with species-unspecific isotope dilution mass spectrometry (IDMS). In order to achieve a homogeneous distribution of both protein and isotope-enriched spike (simulated isotope equilibration), immersing the protein strips with {sup 34}S spike solution after gel electrophoresis was demonstrated to be an effective way of spike addition. Furthermore, effects of immersion time and {sup 34}S spike concentration were investigated to obtain optimal conditions of the post-electrophoresis isotope dilution method. The relative mass of spike and ablated sample (m{sub sp}/m{sub sam}) in IDMS equation was calculated by standard Tf and Alb proteins, which could be applied to the quantification of Tf and Alb in ERM-DA470k/IFCC for method confirmation. The results were in agreement with the certified value with good precision and small uncertainty (1.5–3%). In this method, species-specific spike protein is not necessary and the integrity of the heteroatom-protein could be maintained in sample preparation

  16. Avaliação do vício de "tempo longo" de indicadores internos em ensaio de digestão com ruminantes Evaluation of internal markers long term bias in a digestion assay with ruminants

    Directory of Open Access Journals (Sweden)

    E. Detmann

    2007-02-01

    Full Text Available Realizou-se um ensaio de digestão com 20 ovinos machos, castrados, para avaliar o viés de "tempo longo" (VTL dos indicadores internos: matéria seca indigestível (MSi e fibra em detergente neutro (FDNi e ácido (FDAi indigestíveis. O experimento, com duração de 19 dias, foi implementado em delineamento em blocos completos casualizados, com cinco tratamentos (rações concentradas e quatro blocos. As dietas utilizadas, formuladas para serem isoprotéicas (10% de proteína bruta, apresentaram 60% de feno de capim-coastcross e 40% de concentrado, constituído por milho grão, farelo de soja e casca de café, em diferentes proporções: 0; 6,25; 12,5; 18,75; e 25%. A concentração dos indicadores foi estimada em amostras de alimentos, sobras e fezes, por procedimento de incubação ruminal in situ, durante 144 horas. A relação entre consumo e excreção dos indicadores foi realizada pelo ajustamento de modelo de regressão linear simples, de forma independente dos efeitos fixos de tratamentos e blocos. Verificou-se recuperação completa dos indicadores MSi e FDNi (P>0,30, o que indica ausência de VTL. Observou-se VTL de +25,45 g/dia para a FDAi (PLong term bias (LTB of internal markers indigestible dry matter (iDM, and indigestible neutral (iNDF and acid (iADF detergent fiber in a digestion assay with ruminants was evaluated. Twenty castrated male ovines were managed in metabolic crates. A completely randomized block design with five treatments (concentrate rations and four blocks was used. Diets were isonitrogenous diets (10% of crude protein were formulated to containing 60% of coastcross hay and 40% of concentrate, in dry matter basis. The concentrates were based on corn grain, soybean meal and coffee hulls, in different levels (0, 6.25, 12.5, 18.75, and 25%, as fed-basis. The markers contents in feeds, orts, and feces were estimated by a 144 hours in situ rumen incubation procedure. The relationship between markers intake and fecal

  17. Determination of trace rare earth elements in gadolinium aluminate by inductively coupled plasma time of flight mass spectrometry

    International Nuclear Information System (INIS)

    An analytical methodology was developed for the precise quantification of ten trace rare earth elements (REEs), namely, La, Ce, Pr, Nd, Sm, Eu, Tb, Dy, Ho, and Tm, in gadolinium aluminate (GdAlO3) employing an ultrasonic nebulizer (USN)-desolvating device based inductively coupled plasma mass spectrometry (ICP-MS). A microwave digestion procedure was optimized for digesting 100 mg of the refractory oxide using a mixture of sulphuric acid (H2SO4), phosphoric acid (H3PO4) and water (H2O) with 1400 W power, 10 min ramp and 60 min hold time. An USN-desolvating sample introduction system was employed to enhance analyte sensitivities by minimizing their oxide ion formation in the plasma. Studies on the effect of various matrix concentrations on the analyte intensities revealed that precise quantification of the analytes was possible with matrix level of 250 mg L−1. The possibility of using indium as an internal standard was explored and applied to correct for matrix effect and variation in analyte sensitivity under plasma operating conditions. Individual oxide ion formation yields were determined in matrix matched solution and employed for correcting polyatomic interferences of light REE (LREE) oxide ions on the intensities of middle and heavy rare earth elements (MREEs and HREEs). Recoveries of ≥ 90% were achieved for the analytes employing standard addition technique. Three real samples were analyzed for traces of REEs by the proposed method and cross validated for Eu and Nd by isotope dilution mass spectrometry (IDMS). The results show no significant difference in the values at 95% confidence level. The expanded uncertainty (coverage factor 1σ) in the determination of trace REEs in the samples were found to be between 3 and 8%. The instrument detection limits (IDLs) and the method detection limits (MDLs) for the ten REEs lie in the ranges 1–5 ng L−1 and 7–64 μg kg−1 respectively. - Highlights: • A mixture of H2SO4, H3PO4 and H2O was optimized for

  18. DFM for maskmaking: design-aware flexible mask-defect analysis

    Science.gov (United States)

    Driessen, Frank A. J. M.; Westra, J.; Scheffer, M.; Kawakami, K.; Tsujimoto, E.; Yamaji, M.; Kawashima, T.; Hayashi, N.

    2007-10-01

    We present a novel software system that combines design intent as known by EDA designers with defect inspection results from the maskshop to analyze the severity of defects on photomasks. The software -named Takumi Design- Driven Defect Analyzer (TK-D3A)- analyzes defects by combining actions in the image domain with actions in the design domain and outputs amongst others flexible mask-repair decisions in production formats used by the maskshop. Furthermore, TK-D3A outputs clips of layout (GDS/OASIS) that can be viewed with its graphical user interface for easy review of the defects and associated repair decisions. As inputs the system uses reticle defect-inspection data (text and images) and the respective multi-layer design layouts with the definitions of criticalities. The system does not require confidential design data from IDM, Fabless Design House, or Foundry to be sent to the maskshop and it also has minimal impact on the maskshop's mode of operation. The output of TK-D3A is designed to realize value to the maskshop and its customers in the forms of: 1) improved yield, 2) reduction of delivery times of masks to customers, and 3) enhanced utilization of the maskshop's installed tool base. The system was qualified together with a major IDM on a large set of production reticles in the 90 and beyond-65 nm technology nodes of which results will be presented that show the benefits for maskmaking. The accuracy in detecting defects is extremely high. We show the system's capability to analyze defects well below the pixel resolution of all inspection tools used, as well as the capability to extract multiple types of transmission defects. All of these defects are analyzed design-criticality-aware by TK-D3A, resulting in a large fraction of defects that do not need to be repaired because they are located in non-critical or less-critical parts of the layout, or, more importantly, turn out to be repairable or negligible despite of originally being classified as

  19. KEY COMPARISON: Key comparison CCQM-K60: Total selenium and selenomethionine in selenised wheat flour

    Science.gov (United States)

    Goenaga Infante, Heidi; Sargent, Mike

    2010-01-01

    Key comparison CCQM-K60 was performed to assess the analytical capabilities of national metrology institutes (NMIs) to accurately quantitate the mass fraction of selenomethionine (SeMet) and total selenium (at low mg kg-1 levels) in selenised wheat flour. It was organized by the Inorganic Analysis Working Group (IAWG) of the Comité Consultatif pour la Quantité de Matière (CCQM) as a follow-up key comparison to the previous pilot study CCQM-P86 on selenised yeast tablets. LGC Limited (Teddington, UK) and the Institute for National Measurement Standards, National Research Council Canada (NRCC, Ottawa, Canada) acted as the coordinating laboratories. CCQM-K60 was organized in parallel with a pilot study (CCQM-P86.1) involving not only NMIs but also expert laboratories worldwide, thus enabling them to assess their capabilities, discover problems and learn how to modify analytical procedures accordingly. Nine results for total Se and four results for SeMet were reported by the participant NMIs. Methods used for sample preparation were microwave assisted acid digestion for total Se and multiple-step enzymatic hydrolysis and hydrolysis with methanesulfonic acid for SeMet. For total Se, detection techniques included inductively coupled plasma mass spectrometry (ICP-MS) with external calibration, standard additions or isotope dilution analysis (IDMS); instrumental neutron activation analysis (INAA); and graphite furnace atomic absorption spectrometry (GFAAS) with external calibration. For determination of SeMet in the wheat flour sample, the four NMIs relied upon measurements using species-specific IDMS (using 76Se-enriched SeMet) with HPLC-ICP-MS. Eight of the nine participating NMIs reported results for total Se within 3.5% deviation from the key comparison reference value (KCRV). For SeMet, the four participating NMIs reported results within 3.2% deviation from the KCRV. This shows that the performance of the majority of the CCQM-K60 participants was very good

  20. Lagrangian model of zooplankton dispersion: numerical schemes comparisons and parameter sensitivity tests

    Institute of Scientific and Technical Information of China (English)

    QIU Zhongfeng; Andrea M. DOGLIOLI; HE Yijun; Francois CARLOTTI

    2011-01-01

    This paper presents two comparisons or tests for a Lagrangian model of zooplankton dispersion: numerical schemes and time steps. Firstly, we compared three numerical schemes using idealized circulations. Results show that the precisions of the advanced Adams-Bashfold-Moulton (ABM) method and the Runge-Kutta (RK) method were in the same order and both were much higher than that of the Euler method. Furthermore, the advanced ABM method is more efficient than the RK method in computational memory requirements and time consumption. We therefore chose the advanced ABM method as the Lagrangian particle-tracking algorithm. Secondly, we performed a sensitivity test for time steps, using outputs of the hydrodynamic model, Symphonie. Results show that the time step choices depend on the fluid response time that is related to the spatial resolution of velocity fields. The method introduced by Oliveira et al. in 2002 is suitable for choosing time steps of Lagrangian particle-tracking models, at least when only considering advection.

  1. A multimodal behavioral approach to performance anxiety.

    Science.gov (United States)

    Lazarus, Arnold A; Abramovitz, Arnold

    2004-08-01

    Cognitive-behavior therapy (CBT) stresses a trimodal assessment framework (affect, behavior, and cognition [ABC]), whereas the multimodal approach assesses seven discrete but interactive components--behavior, affect, sensation, imagery, cognition, interpersonal relationships, and drugs/biological factors (BASIC I.D.). Only complex or recalcitrant cases call for the entire seven-pronged range of multimodal interventions. Various case illustrations are offered as examples of how a clinician might proceed when confronted with problems that fall under the general heading of performance anxiety. The main example is of a violinist in a symphony orchestra whose career was in serious jeopardy because of his extreme fear of performing in public. He responded very well to a focused but elaborate desensitization procedure. The hierarchy that was eventually constructed contained many dimensions and subhierarchies featuring interlocking elements that evoked his anxiety. In addition to imaginal systematic desensitization, sessions were devoted to his actual performance in the clinical setting. As a homework assignment, he found it helpful to listen to a long-playing record of an actual rehearsal and to play along with the world-renowned orchestra and conductor. The subsequent disclosure by the client of an important sexual problem was dealt with concomitantly by using a fairly conventional counseling procedure. Therapy required 20 sessions over a 3-month period. PMID:15241811

  2. Off the beaten track: Freud, sound and music. Statement of a problem and some historico-critical notes.

    Science.gov (United States)

    Baralea, Francesco; Minazzi, Vera

    2008-10-01

    The authors note that the element of sound and music has no place in the model of mental functioning bequeathed to us by Freud, which is dominated by the visual and the representational. They consider the reasons for this exclusion and its consequences, and ask whether the simple biographical explanation offered by Freud himself is acceptable. This contribution reconstructs the historical and cultural background to that exclusion, cites some relevant emblematic passages, and discusses Freud's position on music and on the aesthetic experience in general. Particular attention is devoted to the relationship between Freud and Lipps, which is important both for the originality of Lipps's thinking in the turn-of-the-century debate and for his ideas on the musical aspects of the foundations of psychic life, at which Freud 'stopped', as he himself wrote. Moreover, the shade of Lipps accompanied Freud throughout his scientific career from 1898 to 1938. Like all foundations, that of psychoanalysis was shaped by a system of inclusions and exclusions. The exclusion of the element of sound and music is understandable in view of the cultural background to the development of the concepts of the representational unconscious and infantile sexuality. While the consequences have been far reaching, the knowledge accumulated since that exclusion enables us to resume, albeit on a different basis, the composition of the 'unfinished symphony' of the relationship between psychoanalysis and music. PMID:19127875

  3. When Stars Attack! Live Radioactivities as Geological Signatures of Nearby Supernova Explosions

    Science.gov (United States)

    Fields, Brian D.

    2007-05-01

    The lifespans of the most massive stars are a symphony of the fundamental forces, culminating in a spectacular and violent supernova explosion. While these events are awesome to observe, they can take a more sinister shade when they occur closer to home, because an explosion inside a certain "minimum safe distance" would pose a grave threat to life on Earth. We will discuss these cosmic insults to life, and ways to determine whether a supernova occurred nearby over the course of the Earth's existence. We will then present recent evidence that a star exploded near the Earth about 3 million years ago. Radioactive iron-60 atoms have been found in ancient samples of deep-ocean material, and are likely to be debris from this explosion. Recent data confirm this radioactive signal, and for the first time allow sea sediments to be used as a telescope, probing the nuclear reactions that power exploding stars. Furthermore, an explosion so close to Earth was probably a "near-miss," which emitted intense and possibly harmful radiation. The resulting environmental damage may even have led to extinction of species which were the most vulnerable to this radiation.

  4. “纯音乐”的历史内涵%The Historical Connotation of“Absolute Music”

    Institute of Scientific and Technical Information of China (English)

    孙胜华

    2016-01-01

    纯音乐是19世纪重要的音乐命题,常常作为标题音乐对立面而存在。它既与音乐史学现象特别是纯器乐交响曲的发展紧密联系,又关乎此时的音乐美学潮流,尤其体现在瓦格纳和汉斯立克的美学思想中。文章从美学和史学结合的角度试图揭示纯音乐的历史实质,以期进一步认知和评估其历史价值。%The absolute music is an important musical proposition in 19th-centu-ry, and it is frequently existed as the opposite of the programme music. It is not only closely linked to the development of music historical phenomenon especially purely instrumental symphony, but also related to the trend of music aesthetics at that time, particularly reflected in the Wagner and Hanslick’s aesthetic thoughts. From the per-spective of combination aesthetics with history, this paper tried to reveal the histori-cal essence of absolute music, in order to further cognitive and evaluate its historical value.

  5. Concert halls with strong and lateral sound increase the emotional impact of orchestra music.

    Science.gov (United States)

    Pätynen, Jukka; Lokki, Tapio

    2016-03-01

    An audience's auditory experience during a thrilling and emotive live symphony concert is an intertwined combination of the music and the acoustic response of the concert hall. Music in itself is known to elicit emotional pleasure, and at best, listening to music may evoke concrete psychophysiological responses. Certain concert halls have gained a reputation for superior acoustics, but despite the continuous research by a multitude of objective and subjective studies on room acoustics, the fundamental reason for the appreciation of some concert halls remains elusive. This study demonstrates that room acoustic effects contribute to the overall emotional experience of a musical performance. In two listening tests, the subjects listen to identical orchestra performances rendered in the acoustics of several concert halls. The emotional excitation during listening is measured in the first experiment, and in the second test, the subjects assess the experienced subjective impact by paired comparisons. The results showed that the sound of some traditional rectangular halls provides greater psychophysiological responses and subjective impact. These findings provide a quintessential explanation for these halls' success and reveal the overall significance of room acoustics for emotional experience in music performance. PMID:27036257

  6. Diagnostic utility and feasibility on MR virtual endoscopy for hepato-biliary-pancreatic diseases

    International Nuclear Information System (INIS)

    This paper describes examinations to evaluate diagnostic utility and feasibility of MR virtual endoscopy (VE) in the hepato-biliary-pancreatic field. Images are obtained by Siemens Magnetom Symphony Maestro class 1.5T with the prospective acquisition correction-3D-turbo-spin echo (TSE) method under conditions of TR 1,380 ms-TE 395 ms, slice thickness 1 mm and matrix 256 x 256 (1 x 1 x 1 mm) and by procession station of Siemens Leonardo, to compare 2D-HASTE and -RARE images. Examined are optimal MRCP (MR cholangio-pancreatography) imaging, luminal VE imaging with phantom, clinical application of VE with MRI/MRCP, and utility of MR-VE in laparoscopic cholecystectomy. Subjects are images from patients with cholelithiasis (36 cases), cholangiocarcinoma (6), pancreatitis (4), cholangitic cyst (2), and others (2). The bile duct is imaged by VE at 81.4% (cystic), 97.7% (bilateral hepatic) and 88.4% (intrahepatic), and the bifurcating portion at cystic duct in 25 cases of cholecystectomy, at 52.0% by conventional MR/MRCP and 92.0% by 3D-TSE-MR/MRCP+VE. Thus the last method made it possible to evaluate anatomy of the duct system before operation for increasing its safety. (T.I.)

  7. Hans von Bülow: creativity and neurological disease in a famous pianist and conductor.

    Science.gov (United States)

    Wöhrle, Johannes C; Haas, Frithjof

    2007-01-01

    Hans von Bülow (1830-1894) was a conductor and pianist of worldwide reputation and founder of many stylistic interpretations of classic and romantic symphonies. The close friendship with Richard Wagner, but not the enthusiastic admiration of his dramatic musical opus, ended abruptly when Hans von Bülow became aware of the betrayal of his wife Cosima and Richard Wagner. Hans von Bülow reported symptoms and signs of neurological disease in many letters that were kept and edited by his second wife Marie. For decades he suffered from chronic neuralgiforme headaches, which were caused by a tumor of the cervical radicular nerves. At the age of 45 years, he suddenly developed a motorsensory deficit in the right arm and hand and a contralateral facial deficit, suggestive of brainstem infarction. He recovered and celebrated even greater successes as a musician, although phases of major depression also interfered with his professional life. In the last, phase of his life, he experienced the consequences of generalized atherosclerosis and cerebral microangiopathy. It was a second cerebrovascular accident of the brainstem that caused his death, only 10 months after his last concert performance. Although his death occurred in Egypt, an autopsy was performed by Professor Ludwig Edinger and the results will be presented. PMID:17495513

  8. Reassessing the Gravity’s Rainbow Pynchon Wiki: a new research paradigm?

    Directory of Open Access Journals (Sweden)

    Simon Peter Rowberry

    2012-07-01

    Full Text Available Since the 'Against the Day 'Wiki launched in October 2006, the Pynchon Wiki collection has received over twenty thousand edits, making it one of the largest, dedicated literary reference Wikis. One can now view and add annotations to all seven of Pynchon’s novels – only 'Slow Learner 'and his non-fiction remain 'sans 'Wiki -, and a loose community of over four hundred contributors have done so. This paper will assess the importance of the 'Gravity’s Rainbow 'Wiki in transforming understanding and interpretation through asking four different questions: does the Wiki count as a disruptive force in the Pynchon interpretive industry, who contributes to the Wiki, what types of contribution they make, and how do they exploit the hypertextual features on offer through the MediaWiki package. I will suggest that the Pynchon Wiki does not fully depart from old media forms of interpretation and remains fragmented in both community, resembling a symphony of soloists, and potential connections. This is a version of Web 2.0 synthesizing both Darcy DiNucci’s original dystopian vision of fragmentation (DiNucci and Tim O’Reilly’s utopian idea of harnessing ‘collective intelligence’ (O’Reilly.

  9. Reassessing the Gravity’s Rainbow Pynchon Wiki: a new research paradigm?

    Directory of Open Access Journals (Sweden)

    Simon Peter Rowberry

    2012-07-01

    Full Text Available Since the Against the Day Wiki launched in October 2006, the Pynchon Wiki collection has received over twenty thousand edits, making it one of the largest, dedicated literary reference Wikis. One can now view and add annotations to all seven of Pynchon’s novels – only Slow Learner and his non-fiction remain sans Wiki -, and a loose community of over four hundred contributors have done so. This paper will assess the importance of the Gravity’s Rainbow Wiki in transforming understanding and interpretation through asking four different questions: does the Wiki count as a disruptive force in the Pynchon interpretive industry, who contributes to the Wiki, what types of contribution they make, and how do they exploit the hypertextual features on offer through the MediaWiki package. I will suggest that the Pynchon Wiki does not fully depart from old media forms of interpretation and remains fragmented in both community, resembling a symphony of soloists, and potential connections. This is a version of Web 2.0 synthesizing both Darcy DiNucci’s original dystopian vision of fragmentation (DiNucci and Tim O’Reilly’s utopian idea of harnessing ‘collective intelligence’ (O’Reilly.

  10. Polarized Synchrotron Emissivities and Absorptivities for Relativistic Thermal, Power-law, and Kappa Distribution Functions

    Science.gov (United States)

    Pandya, Alex; Zhang, Zhaowei; Chandra, Mani; Gammie, Charles F.

    2016-05-01

    Synchrotron emission and absorption determine the observational appearances of many astronomical systems. In this paper, we describe a numerical scheme for calculating synchrotron emissivities and absorptivities in all four Stokes parameters for arbitrary gyrotropic electron distribution functions, building on earlier work by Leung, Gammie, and Noble. We use this technique to evaluate the emissivities and the absorptivities for a thermal (Maxwell–Jüttner), isotropic power-law, and an isotropic kappa distribution function. The latter contains a power-law tail at high particle energies that smoothly merges with a thermal core at low energies, as is characteristic of observed particle spectra in collisionless plasmas. We provide fitting formulae and error bounds on the fitting formulae for use in codes that solve the radiative transfer equation. The numerical method and the fitting formulae are implemented in a compact C library called symphony. We find that the kappa distribution has a source function that is indistinguishable from a thermal spectrum at low frequency and transitions to the characteristic self-absorbed synchrotron spectrum, \\propto {ν }5/2, at high frequency; the linear polarization fraction for a thermal spectrum is near unity at high frequency; and all distributions produce O(10%) circular polarization at low frequency for lines of sight sufficiently close to the magnetic field vector.

  11. On the road to obesity: Television viewing increases intake of high-density foods.

    Science.gov (United States)

    Blass, Elliott M; Anderson, Daniel R; Kirkorian, Heather L; Pempek, Tiffany A; Price, Iris; Koleini, Melanie F

    2006-07-30

    Television viewing (TVV) has been linked with obesity, possibly through increased sedentary behavior and/or through increased ingestion during TVV. The proposition that TVV causes increased feeding, however, has not been subjected to experimental verification until recently. Our objective was to determine if the amount eaten of two familiar, palatable, high-density foods (pizza and macaroni and cheese) was increased during a 30-min meal when watching TV. In a within-subjects design, one group of undergraduates (n = 10) ate pizza while watching a TV show of their choice for one session and when listening to a symphony during the other session. A second group of undergraduates (n = 10) ate macaroni and cheese (M&C). TVV increased caloric intake by 36% (one slice on average) for pizza and by 71% for M&C. Eating patterns also differed between conditions. Although the length of time to eat a slice of pizza remained stable between viewing conditions, the amount of time before starting another slice was shorter during TVV. In contrast, M&C was eaten at a faster rate and for a longer period of time during TVV. Thus, watching television increases the amount eaten of high-density, palatable, familiar foods and may constitute one vector contributing to the current obesity crisis. PMID:16822530

  12. The elegant universe. Superstrings, hidden dimensions, and the search for the world formula

    International Nuclear Information System (INIS)

    Brian Greene, physicists and author of bestsellers, presents in this impressive three-part documentation one of the most exciting ideas, which human mind ever has thought - the longly searched ''theory of all'', the so-called world formula. Even Albert Einstein searched for decades of his live for this formula - and falled. Scientists of our time now believe to have solved the puzzle of the world formula - with the string theory. The fundamental idea of the string theory is fascinating. All in our world, from the smallest atoms up to the mostly distant galaxies, consists of unimaginably small energy fathoms, the strings. And it are the different vibrations of the string, which determine all matter and energy - the universe, a grandious cosmic symphony. Brian Greene is one of the leading string theoreticians. The documentation is based on his homonymous bestseller. Nobody else could present this theme such easily and with so much humor. In the USA the program was awarded with the Peabody Award, the ''Oscar'' for documentations

  13. 《瑞士游记》钢琴音乐的文学完美性%Lester's “Travels in Switzerland” Piano Music Literature Perfect Interpretation

    Institute of Scientific and Technical Information of China (English)

    邵红红

    2012-01-01

    文章以李斯特的钢琴作品《瑞士游记》为例进行分析,根据音乐作品中的民族性以及宗教影响来分析钢琴音乐对文学作品的诠释,并分别从诗歌的标题形式、宣叙性主题和诗意化的个性旋律三方面入手,剖析文学作品在钢琴音乐中的演绎过程,促进听众对李斯特作品的理解。%Folanci. Lester in nineteenth Century is the famous pianist, in his piano works the achieve- ments of his career up to the peak, the first symphonic poem, poetry content and emotion expression in symphonic music, to further expand and deepen the connotation of the later symphony, music creation pro- duced bigger effect. The piano works of Lester "travels in Switzerland" as an example, according to the music in the ethnic and religious influences to the analysis of piano music works of literature interpreta- tion, and separately from the title of the poem form of recitative, theme and poetic personality theme three aspects, analysis of literary works in piano music deductive process, promote the audience knowledge of Lester's works.

  14. 柴可夫斯基艺术歌曲中的艺术特征分析%Analysis of the artistic characteristics of Tchaikovsky's art songs

    Institute of Scientific and Technical Information of China (English)

    张涛

    2013-01-01

      柴可夫斯基一生的成就以歌剧、芭蕾舞剧和交响乐最为突出,艺术歌曲虽然不是很多,但依然是俄罗斯音乐史上不朽的经典。本文从音乐与自然的结合、音乐与性格、音乐与诗词、音乐与钢琴伴奏四个方面,对柴可夫斯基斯基艺术歌曲的艺术特征进行了分析。%Tchaikovsky lifetime achievement in opera, ballet and symphony most prominent art song, though not a lot, but still enduring classics in the history of Russian music. In this paper, the combination of music and nature, music and personality, music and poetry, music and piano accompaniment four aspects, Tchaikovsky Chomsky Lieder artistic characteristics were analyzed.

  15. Gala Concert for the 50th Anniversary of CERN

    CERN Multimedia

    2004-01-01

    The CERN 50th Anniversary celebrations will wrap up with music on 18 December with a Gala Concert by the Philharmonic Orchestra of London in Victoria Hall, Geneva. The orchestra will be directed by Tommaso Placidi, a young talented conductor, and will also enjoy the presence of Maxim Vengerov as first violin. This evening is organised by Mrs Suzanne Hurter, with the support of private companies as well as of the city and the canton of Geneva. The concert will begin with the Overture of Wagner's Flying Dutchman. Maxim Vengerov will then interpret Beethoven's Concert for violin and orchestra. The second part of the concert will be devoted to Tschaikovsky's Fourth Symphony. Tickets cost between 35CHF and 140 CHF according to the seat. People working at CERN will have a 10% discount. You may buy your tickets at the Kiosque FK inside the building Pfister Meubles in Meyrin (ch de Rianbosson 5-9) and get your discount by showing your CERN card. Find out more about the seats available, go to the Resaplus Ticket Book...

  16. 猪O型FMDV主要抗原表位多肽的合成与鉴定%Synthesis and Identification of Key Protective Antigen Peptides of Foot-and-mouth Disease Virus

    Institute of Scientific and Technical Information of China (English)

    杨苏珍; 赵冬; 郅玉宝; 邓瑞广; 张改平

    2014-01-01

    为筛选口蹄疫病毒表位抗原,使用Symphony 12通道多肽合成仪,采用Fmoc固相合成原理,合成5条O型FMDV抗原表位肽.Quattro Micro液-质联用仪分析多肽分子的结构特性,分析结果表明,在误差允许的范围内所检测的结果与理论值相符,5条多肽均通过质谱检测.通过SMCC双功能偶联剂将多肽偶联于BSA载体蛋白,以Dot-blot和间接ELISA法检测这5条与BSA偶联得多肽与O型FMDV阳性血清的结合能力,结果显示,中和表位Pep1、Pep2、Pep3能特异性结合O型FMDV感染血清和免疫血清,为抗FMDV中和表位单克隆抗体的制备和FMDV抗体检测试纸条方法的建立奠定基础.

  17. The role of estradiol in male reproductive function.

    Science.gov (United States)

    Schulster, Michael; Bernie, Aaron M; Ramasamy, Ranjith

    2016-01-01

    Traditionally, testosterone and estrogen have been considered to be male and female sex hormones, respectively. However, estradiol, the predominant form of estrogen, also plays a critical role in male sexual function. Estradiol in men is essential for modulating libido, erectile function, and spermatogenesis. Estrogen receptors, as well as aromatase, the enzyme that converts testosterone to estrogen, are abundant in brain, penis, and testis, organs important for sexual function. In the brain, estradiol synthesis is increased in areas related to sexual arousal. In addition, in the penis, estrogen receptors are found throughout the corpus cavernosum with high concentration around neurovascular bundles. Low testosterone and elevated estrogen increase the incidence of erectile dysfunction independently of one another. In the testes, spermatogenesis is modulated at every level by estrogen, starting with the hypothalamus-pituitary-gonadal axis, followed by the Leydig, Sertoli, and germ cells, and finishing with the ductal epithelium, epididymis, and mature sperm. Regulation of testicular cells by estradiol shows both an inhibitory and a stimulatory influence, indicating an intricate symphony of dose-dependent and temporally sensitive modulation. Our goal in this review is to elucidate the overall contribution of estradiol to male sexual function by looking at the hormone's effects on erectile function, spermatogenesis, and libido. PMID:26908066

  18. Whole-body MRA on a rolling table platform (AngioSURF)

    International Nuclear Information System (INIS)

    Purpose: Development of a technique for whole-body MR angiography based on a rolling table platform and integration of a surface coil. Material and Methods: The developed rolling table platform AngioSURF (System for Unlimited Rolling Field-of-view) with integrated surface coil can be mounted on top of the original patient table of a Siemens Symphony System. Data acquisition was performed with a standard body array surface coil. The system was tested on three volunteers and one patient with angiographically documented vascular pathology. Data acquisition was performed with a 3D-FLASH-sequence (TR/TE 2,1/0,7 ms, flip angle: 20 , FOV 40x40 cm, 80 partitions, matrix 512x420 with zero interpolation). Five data sets were collected in immediate succession during continuous injection of a paramagnetic contrast agent. Time of acquisition per data set was 10 seconds. Table repositioning was performed manually within 3 seconds. Thus, the total acquisition time amounted to 72 seconds. Results: No problems with handling occurred in any of the four cases. The excellent image quality enables detailed assessment of the displayed vascular territories. Conclusions: The rolling table platform with integrated surface coil (AngioSURF) allows diagnostic display of the arterial vascular system from supraaortic vessels to the distal trifurcation arteries in only 72 seconds. (orig.)

  19. Disentangling preference ratings of concert hall acoustics using subjective sensory profiles.

    Science.gov (United States)

    Lokki, Tapio; Pätynen, Jukka; Kuusinen, Antti; Tervo, Sakari

    2012-11-01

    Subjective evaluation of acoustics was studied by recording nine concert halls with a simulated symphony orchestra on a seat 12 m from the orchestra. The recorded music was spatially reproduced for subjective listening tests and individual vocabulary profiling. In addition, the preferences of the assessors and objective parameters were gathered. The results show that concert halls were discriminated using perceptual characteristics, such as Envelopment/Loudness, Reverberance, Bassiness, Proximity, Definition, and Clarity. With these perceptual dimensions the preference ratings can be explained. Seventeen assessors were divided into two groups based on their preferences. The first group preferred concert halls with relatively intimate sound, in which it is quite easy to hear individual instruments and melody lines. In contrast, the second group preferred a louder and more reverberant sound with good envelopment and strong bass. Even though all halls were recorded exactly at the same distance, the preference is best explained with subjective Proximity and with Bassiness, Envelopment, and Loudness to some extent. Neither the preferences nor the subjective ratings could be fully explained by objective parameters (ISO3382-1:2009), although some correlations were found. PMID:23145600

  20. Value of Dual Energy Computed Tomography for detection of myocardial iron deposition in Thalassaemia patients: Initial experience

    Energy Technology Data Exchange (ETDEWEB)

    Hazirolan, Tuncay; Akpinar, Burcu [Hacettepe University Medical School, Department of Radiology, Ankara (Turkey); Unal, Sule; Guemruek, Fatma [Hacettepe University Medical School, Department of Pediatrics, Ankara (Turkey); Haliloglu, Mithat [Hacettepe University Medical School, Department of Radiology, Ankara (Turkey); Alibek, Sedat [Hacettepe University Medical School, Department of Radiology, Ankara (Turkey); Radiology Institute, University of Erlangen/Nurnberg, 91054 Erlangen (Germany)], E-mail: sedat.alibek@uk-erlangen.de

    2008-12-15

    Purpose: The aim of our study was to compare the value of cardiac DECT (cDECT) for detection of myocardial iron deposition to T2*w cardiac MRI (cMRI). Material and methods: Nineteen patients with clinical history of Thalassaemia underwent T2*-weighted cardiac MRI (cMRI) with a 1.5 T MR scanner (MAGNETOM Symphony, Siemens Medical Solutions, Erlangen, Germany) and cardiac dual energy CT (cDECT) with a DSCT scanner (SOMATOM Definition, Siemens Medical Solutions, Erlangen, Germany) on the same day. HU values obtained from cDECT scans and T2*-values from cMRI were statistically correlated to calculate significance levels. Table times were measured for both cDECT and cMRI and compared. Patients were asked to grade their subjective comfort during the examination. Results: In all patients cDECT scans were successfully acquired. HU values of septal muscle correlated strongly with T2*-values, whereas no correlation was found for paraspinal muscle. Table time was significantly shorter for cDECT compared to cMRI (mean: 3.7 min vs. 11.2 min) and subjective patient comfort was rated comfortable for cDECT and average to poor for cMRI. Mean radiation dose was 0.71 mSv. Conclusion: cDECT scans seem to be possible for evaluation of myocardial iron load in pediatric Thalassaemia patients.

  1. Value of Dual Energy Computed Tomography for detection of myocardial iron deposition in Thalassaemia patients: Initial experience

    International Nuclear Information System (INIS)

    Purpose: The aim of our study was to compare the value of cardiac DECT (cDECT) for detection of myocardial iron deposition to T2*w cardiac MRI (cMRI). Material and methods: Nineteen patients with clinical history of Thalassaemia underwent T2*-weighted cardiac MRI (cMRI) with a 1.5 T MR scanner (MAGNETOM Symphony, Siemens Medical Solutions, Erlangen, Germany) and cardiac dual energy CT (cDECT) with a DSCT scanner (SOMATOM Definition, Siemens Medical Solutions, Erlangen, Germany) on the same day. HU values obtained from cDECT scans and T2*-values from cMRI were statistically correlated to calculate significance levels. Table times were measured for both cDECT and cMRI and compared. Patients were asked to grade their subjective comfort during the examination. Results: In all patients cDECT scans were successfully acquired. HU values of septal muscle correlated strongly with T2*-values, whereas no correlation was found for paraspinal muscle. Table time was significantly shorter for cDECT compared to cMRI (mean: 3.7 min vs. 11.2 min) and subjective patient comfort was rated comfortable for cDECT and average to poor for cMRI. Mean radiation dose was 0.71 mSv. Conclusion: cDECT scans seem to be possible for evaluation of myocardial iron load in pediatric Thalassaemia patients

  2. Bringing Astronomy Directly to New Audiences (50,000 People) at Outdoor Concerts and Music Festivals

    Science.gov (United States)

    Lubowich, D.

    2014-07-01

    My NASA-funded Music and Astronomy Under the Stars (MAUS) has brought astronomy to 50,000 music lovers at the National Mall (co-sponsor OSTP); Central Park Jazz, Newport Folk, Ravinia, or Tanglewood music festivals; and classical, folk, pop/rock, opera, Caribbean, or county-western concerts in parks assisted by astronomy clubs (55 events since 2009). Yo-Yo-Ma, the Chicago and Boston Symphony Orchestras, Ravi Coltrane, Esperanza Spalding, Phish, Blood Sweat and Tears, Deep Purple, Tony Orlando, and Wilco performed at these events. MAUS combines solar, optical, and radio telescope observations; large posters/banners (From the Earth to the Universe; Visions of the Universe); videos; hands-on activities (Night Sky Network; Harvard-Smithsonian CfA); imaging with a cell phone mount; and hand-outs (info on science museums, astronomy clubs, and citizen science) before and after the concerts or at intermission. MAUS reached underserved groups and attracted large enthusiastic crowds. Many young children participated in this family learning experience-often the first time they looked through a telescope. Outcomes: While < 50% of the participants took part in a science museum or activity in the past year (survey result), they found MAUS enjoyable and understandable; learned about astronomy; wanted to learn more; and increased their interest in science (ave. rating 3.6/4). Taking science directly to people is effective in promoting science education!

  3. Hawaiian Starlight: Sharing the Beauty of the Hawaiian Skies

    Science.gov (United States)

    Cuillandre, J. C.

    Canada-France-Hawaii Telescope Corp. The summit of Mauna Kea (14,000 feet) offers the best viewing of the Cosmos in the northern hemisphere, and the film "Hawaiian Starlight" delivers a pure esthetic experience from the mountain into the Universe. Seven years in the making, this cinematic symphony reveals the spectacular beauty of the mountain and its connection to the Cosmos through the magical influence of time-lapse cinematography scored exclusively (no narration) with the awe-inspiring, critically acclaimed, Halo music by Martin O'Donnell and Michael Salvatori. Daytime and nighttime landscapes and skyscapes alternate with stunning true color images of the Universe captured by an observatory on Mauna Kea, all free of any computer generated imagery. An extended segment of the film will be presented at the Advanced Maui Optical and Space Surveillance Technologies Conference to celebrate the international year of Astronomy 2009, a global effort initiated by the IAU (International Astronomical Union) and UNESCO (United Nations Educational, Scientific and Cultural Organization) to help the citizens of the world rediscover their place in the Universe through the day- and night-time sky, and thereby engage a personal sense of wonder and discovery. Hawaiian Starlight is true to this commitment. The inspiration and technology of the film will be shortly presented by the film's director.

  4. MR Imaging in Diagnosis of Pelvic Floor Descent: Supine versus Sitting Position

    Directory of Open Access Journals (Sweden)

    Francesca Iacobellis

    2016-01-01

    Full Text Available Introduction. Functional disorders of the pelvic floor represent have a significant impact on the quality of life. The advent of open-configuration systems allowed for the evaluation of defecation with MR imaging in sitting position. The purpose of the present study is to compare the results of static and dynamic pelvic MR performed in supine position versus sitting position, using a new MR prototype machine, in the diagnosis of pelvic floor descent. Materials and Methods. Thirty-one patients with pelvic floor disorders were enrolled, and underwent MR Defecography in supine position with 1.5 T closed magnet (MAGNETOM Symphony, Siemens, Germany and in sitting position with a 0.25-Tesla open magnet system (G-Scan ESAOTE, Italy. Results. In rest and squeezing phases, positions of bladder, vagina, and ARJ were significantly different when the patient was imaged in supine versus sitting position. In the defecation phase, a significant difference for the bladder and vagina position was detected between the two exams whereas a significant difference for the ARJ was not found. A statistically significant difference exists when the pelvic floor descent is evaluated in sitting versus supine position. Conclusion. Our results show that MR Defecography in sitting position may represent a useful tool to correctly diagnose and grade the pelvic organ descent.

  5. MR Imaging in Diagnosis of Pelvic Floor Descent: Supine versus Sitting Position

    Science.gov (United States)

    Renzi, Adolfo; Monaco, Luigi; Serra, Nicola; Feragalli, Beatrice; Iacomino, Aniello; Brunese, Luca; Cappabianca, Salvatore

    2016-01-01

    Introduction. Functional disorders of the pelvic floor represent have a significant impact on the quality of life. The advent of open-configuration systems allowed for the evaluation of defecation with MR imaging in sitting position. The purpose of the present study is to compare the results of static and dynamic pelvic MR performed in supine position versus sitting position, using a new MR prototype machine, in the diagnosis of pelvic floor descent. Materials and Methods. Thirty-one patients with pelvic floor disorders were enrolled, and underwent MR Defecography in supine position with 1.5 T closed magnet (MAGNETOM Symphony, Siemens, Germany) and in sitting position with a 0.25-Tesla open magnet system (G-Scan ESAOTE, Italy). Results. In rest and squeezing phases, positions of bladder, vagina, and ARJ were significantly different when the patient was imaged in supine versus sitting position. In the defecation phase, a significant difference for the bladder and vagina position was detected between the two exams whereas a significant difference for the ARJ was not found. A statistically significant difference exists when the pelvic floor descent is evaluated in sitting versus supine position. Conclusion. Our results show that MR Defecography in sitting position may represent a useful tool to correctly diagnose and grade the pelvic organ descent. PMID:26880893

  6. Concert halls with strong lateral reflections enhance musical dynamics.

    Science.gov (United States)

    Pätynen, Jukka; Tervo, Sakari; Robinson, Philip W; Lokki, Tapio

    2014-03-25

    One of the most thrilling cultural experiences is to hear live symphony-orchestra music build up from a whispering passage to a monumental fortissimo. The impact of such a crescendo has been thought to depend only on the musicians' skill, but here we show that interactions between the concert-hall acoustics and listeners' hearing also play a major role in musical dynamics. These interactions contribute to the shoebox-type concert hall's established success, but little prior research has been devoted to dynamic expression in this three-part transmission chain as a complete system. More forceful orchestral playing disproportionately excites high frequency harmonics more than those near the note's fundamental. This effect results in not only more sound energy, but also a different tone color. The concert hall transmits this sound, and the room geometry defines from which directions acoustic reflections arrive at the listener. Binaural directional hearing emphasizes high frequencies more when sound arrives from the sides of the head rather than from the median plane. Simultaneously, these same frequencies are emphasized by higher orchestral-playing dynamics. When the room geometry provides reflections from these directions, the perceived dynamic range is enhanced. Current room-acoustic evaluation methods assume linear behavior and thus neglect this effect. The hypothesis presented here is that the auditory excitation by reflections is emphasized with an orchestra forte most in concert halls with strong lateral reflections. The enhanced dynamic range provides an explanation for the success of rectangularly shaped concert-hall geometry. PMID:24591584

  7. Agent based models for testing city evacuation strategies under a flood event as strategy to reduce flood risk

    Science.gov (United States)

    Medina, Neiler; Sanchez, Arlex; Nokolic, Igor; Vojinovic, Zoran

    2016-04-01

    This research explores the uses of Agent Based Models (ABM) and its potential to test large scale evacuation strategies in coastal cities at risk from flood events due to extreme hydro-meteorological events with the final purpose of disaster risk reduction by decreasing human's exposure to the hazard. The first part of the paper corresponds to the theory used to build the models such as: Complex adaptive systems (CAS) and the principles and uses of ABM in this field. The first section outlines the pros and cons of using AMB to test city evacuation strategies at medium and large scale. The second part of the paper focuses on the central theory used to build the ABM, specifically the psychological and behavioral model as well as the framework used in this research, specifically the PECS reference model is cover in this section. The last part of this section covers the main attributes or characteristics of human beings used to described the agents. The third part of the paper shows the methodology used to build and implement the ABM model using Repast-Symphony as an open source agent-based modelling and simulation platform. The preliminary results for the first implementation in a region of the island of Sint-Maarten a Dutch Caribbean island are presented and discussed in the fourth section of paper. The results obtained so far, are promising for a further development of the model and its implementation and testing in a full scale city

  8. Physics For All -- yes, it's real physics

    Science.gov (United States)

    Eisenkraft, Arthur

    2012-02-01

    Can ``all'' students learn ``real'' physics? We want to provide instruction to a wider segment of the population including those students who will not go into STEM (Science, Technology, Engineering, Math) careers. We also want to maintain the integrity of physics, challenge all students, and not compromise the rigor of our courses. Accomplishing this requires a research guided approach to instruction, curriculum and assessment. Physics First and Physics for All have become a success story for thousands of students in urban, suburban, and rural districts. At the same time, the International Physics Olympiad and other competitions have raised the expectation of what the most motivated students can achieve. Many physics educators are exploring ways to set higher goals for our most gifted students while also providing physics instruction to students previously excluded from our physics classes. Many of the same issues that K-12 educators are struggling with are equally important to the college community as colleges try to educate both future physicists and an educated citizenry. Great novels and symphonies are accessible to people of different backgrounds and levels of expertise. We should develop strategies that enable us to share an understanding of physics with all students because everyone deserves an opportunity to reflect on the wondrous workings of our universe.

  9. Celebrating 24 years of Public Outreach of Science and Engineering in Portland Oregon

    Science.gov (United States)

    Bristol, Terry

    2012-02-01

    There have been several core strategies in our highly successful 24-year Science, Technology and Society outreach program. However, the strategy for each season is also dynamic, requiring innovation and novel coalitions. As Bob Dylan put it so succinctly, ``He not busy being born is busy dying.'' Public outreach programs - as the Chautauquas of the past - should be positioned in the cultural milieu along with the opera, symphony and theatre. Support for the enterprise needs to be a broad and diverse coalition, based ideally on the creative formation of win-win relationship. You want people to see your success as their success: ``Together we can enhance the intellectual environment in ways that none of us could do alone.'' Being multi-disciplinary presents challenges but has considerable advantages. For instance, enlightened managers of established organizations recognize the value of exposing their employees to a diversity of problem solving approaches. Instead of inviting speakers for one large lecture we now invite them to be Resident Scholars for two-three days and develop a range of additional smaller public engagements. Science and engineering topics must be relevant - placed in the broader Science, Technology and Society framework. We avoid ``gee-whiz'' in favor of what stimulates reflection on who we are, where we came from, and our role in the universe. I will briefly review how we have survived and thrived and, finally, what I see as future trends and opportunities.

  10. Differential diagnosis of benign and malignant breast lesions by combination of enhanced dynamic MRI and diffusion weighted MRI. Examination by ROC analysis

    International Nuclear Information System (INIS)

    A highly improved differential diagnosis of benign and malignant breast lesions by combination of MR-spectroscopy and enhanced dynamic (ED) MRI has been reported but the former imaging requires as long as 12-20 min. The present examination is performed to know whether combination of ED MRI and diffusion weighted (DW) MRI which is done within 40-100 sec, can also have the high diagnostic accuracy. Objects are 226 lesion images of 219 women of the average age of 54.3 y, whose histopathological observation is conducted on tissues obtained by surgery or biopsy after imaging. MRI machine is Siemens 1.5 T Symphony with the coil specific for mammary gland and imaging is done in the order of short inversion time inversion recovery (STIR), DW, and ED with gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA). Images are evaluated by 2 experts according to breast imaging reporting and data system (BI-RADS) MRI of American College of Radiology; detectability, by reference to pathological findings; and differential, by ROC (receiver operating characteristics) analysis (ROCFIT program) and Mc-Nemar test. Pathological diagnosis gives 196 malignant and 30 benign lesions. DW MRI is found to be only subsidiary for differential examination of malignant and benign lesions. (R.T.)

  11. Urban sound ecologies

    Directory of Open Access Journals (Sweden)

    Sanne Krogh Groth

    2013-12-01

    Full Text Available Within recent years, there has been a renewed focus on sound in urban environments. From sound installations in public space to sound festivals in alternative settings, we find a common interest in sound art relating to the urban environment. Artworks or interventions presented in such contexts share the characteristics of site specificity. However, this article will consider the artwork in a broader context by re-examining how sound installations relate to the urban environment. For that purpose, this article brings together ecology terms from acoustic ecology of the sound theories of the 1970s while developing them into recent definitions of ecology in urban studies. Finally, we unfold our framing of urban sound ecologies with three case analyses: a sound intervention in Berlin, a symphony for wind instruments in Copenhagen and a video walk in a former railway station in Kassel. The article concludes that the ways in which recent sound installations work with urban ecologies vary. While two of the examples blend into the urban environment, the other transfers the concert format and its mode of listening to urban space. Last, and in accordance with recent soundscape research, we point to how artists working with new information and media technologies create inventive ways of inserting sound and image into urban environments.

  12. VLAD DRACULA, THE PRINCE OF TERROR – THE UNDYING MONSTER, EVER RECALLED SINCE 1897 AS AN IMMINENT PRESENCE OF UNDYING FEAR IN FICTION AND FILM

    Directory of Open Access Journals (Sweden)

    K.Rizwana Sultana

    2014-10-01

    Full Text Available The story of Count Dracula remains a fascination for every one irrespective of age and place. Ever since the publication of Dracula as a novel by Bram Stoker in 1897, it led to tremendous translations in to films, adaptation as children’s comic, plays, short story and what not. It is true to say that a literary work of worth with stands the passage of time. Not only the novel of Bram Stoker but the story of the Count Dracula which is also regarded a legend has conquered the world of vampire stories; where Dracula is termed as the King of the vampire world. Though an associate of Satan, at times Dracula finds a place for a romantic hero too. Dracula has enjoyed enormous popularity since its publication and has spawned an extraordinary vampire subculture in the second half of the 20th century. More than 200 films have been made that feature Count Dracula. At the centre of this subculture is the legend of Transylvania, which has become almost synonymous with vampires. The present paper is an attempt to discuss how Dracula was represented in the novel and some film versions of the same. The films focused at are F.W.Murnu’s Nosferatu, the Symphony of Horror (1922, Dracula (1931 and Bram Stoker’s Dracula 1992 and Bram Stoker’s Dracula (1992.

  13. Preoperative rectal cancer staging with phased-array MR

    International Nuclear Information System (INIS)

    We retrospectively reviewed magnetic resonance (MR) images of 96 patients with diagnosis of rectal cancer to evaluate tumour stage (T stage), involvement of mesorectal fascia (MRF), and nodal metastasis (N stage). Our gold standard was histopathology. All studies were performed with 1.5-T MR system (Symphony; Siemens Medical System, Erlangen, Germany) by using a phased-array coil. Our population was subdivided into two groups: the first one, formed by patients at T1-T2-T3, N0, M0 stage, whose underwent MR before surgery; the second group included patients at Tx N1 M0 and T3-T4 Nx M0 stage, whose underwent preoperative MR before neoadjuvant chemoradiation therapy and again 4-6 wks after the end of the treatment for the re-staging of disease. Our gold standard was histopathology. MR showed 81% overall agreement with histological findings for T and N stage prediction; for T stage, this rate increased up to 95% for pts of group I (48/96), while for group II (48/96) it decreased to 75%. Preoperative MR prediction of histologically involved MRF resulted very accurate (sensitivity 100%; specificity 100%) also after chemoradiation (sensitivity 100%; specificity 67%). Phased-array MRI was able to clearly estimate the entire mesorectal fat and surrounding pelvic structures resulting the ideal technique for local preoperative rectal cancer staging

  14. 胶片上的缪斯——歌剧电影指南(二)

    Institute of Scientific and Technical Information of China (English)

    司马勤(Ken Smith); 李正欣(译)

    2011-01-01

    时间过得真快,我还在猜想《华尔街时报》记者海蒂·威尔松(Heidi Waleson)发表《在大屏幕看歌剧》这篇文章所提及"在电影院看歌剧是令人惊讶的新颖商机"的真正意义。她针对的,应该是"商机"这两字吧。无可否认,大都会歌剧院的现场高清转播,早就被公认为划时代的壮举。今天,在交响空间(Symphony Space),一个位于纽约上西城(Upper WestSide)的社区文化中心,你可购票欣赏多个欧洲歌剧院转播的演出,比如米兰的斯卡拉,还有伦敦皇家歌剧院。这些歌剧院都借鉴大都会的模式,把现场演出(或者现场录像)摆上大银幕,让这门艺术更大众化。你吃不吃爆米花,是你的选择。

  15. Astronomy in Brazilian music and poetry

    Science.gov (United States)

    de Freitas Mourão, Ronaldo Rogério

    2011-06-01

    The rôle of astronomy in the Brazilian cultural diversity -though little known world- has been enormous. Thus, the different forms of popular music and erudite, find musical compositions and lyrics inspired by the stars, the eclipses in rare phenomena such as the transit of Venus in front of the sun in 1882, the appearance of Halley's Comet in 1910, in the Big Bang theory. Even in the carnival parades of the blocks at the beginning of the century astronomy was present. More recently, the parade of 1997, the samba school Unidos do Viradouro, under the direction of Joãozinho Trinta, offered a new picture of the first moments of the creation of the universe to join in the white and dark in the components of their school, the idea of matter and anti-matter that reigned in the early moments of the creation of the universe in an explosion of joy. Examples in classical music include Dawn of Carlos Gomes and Carta Celeste by Almeida Prado. Unlike The Planets by Gustav Holst -who between 1914 and 1916 composed a symphonical tribute to the solar system based on astrology- Almeida Prado composed a symphony that is not limited to the world of planets, penetrating the deep cosmos of galaxies. Using various resources of the technique for the piano on the clusters and static movements, violent conflicts between the records of super acute and serious instrument, harpejos cross, etc . . .

  16. Listening to the acoustics in concert halls

    Science.gov (United States)

    Beranek, Leo L.; Griesinger, David

    2001-05-01

    How does acoustics affect the symphonic music performed in a concert hall? The lecture begins with an illustrated discussion of the architectural features that influence the acoustics. Boston Symphony Hall, which was built in 1900 when only one facet of architectural design was known, now rates as one of the world's great halls. How this occurred will be presented. Music is composed with some acoustical environment in mind and this varies with time from the Baroque to the Romantic to the Modern musical period. Conductors vary their interpretation according to the hall they are in. Well-traveled listeners and music critics have favorite halls. The lecture then presents a list of 58 halls rank ordered according to their acoustical quality based on interviews of music critics and conductors. Modern acoustical measurements made in these halls are compared with their rankings. Music recordings will be presented that demonstrate how halls sound that have different measured acoustical parameters. Photographs of a number of recently built halls are shown as examples of how these known acoustical factors have been incorporated into architectural design.

  17. Strawinskys Transformation des Urbanen

    Directory of Open Access Journals (Sweden)

    Monika Woitas

    2010-09-01

    Full Text Available After 1900 there were new technical inventions like cars, aeroplanes, or locomotives on the one hand, crowded streets and factories on the other, which fundamentally changed the experience of space and time. Simultaneity, motor activity, and montage replaced traditional structures and demanded new modes of perception. Linear development as known in classical drama as well as in symphony or opera appeared increasingly anachronistic. Life at its core was now kinetic and marked by machine-like ‚steely‘ rhythms. In the stage works of Igor Stravinsky these changes are transformed into a musical and scenic language: music is no longer merely sound, it is also and always motoric action; construction and montage are the main principles of this ‚new music‘; the development of themes is replaced by sequences of sound images. The present paper follows these transformations of urban life from Petrouchka (1911 to Le Sacre du Printemps (1913, Les Noces (1914-23, and finally Histoire du Soldat (1918.

  18. 金钟盛会华彩献礼--评“第十届中国音乐金钟奖开幕式音乐会”兼及“国家级音乐表演实验教学示范中心”之观察%Review of“The Opening Concert of the 10th Chinese Golden Bell Award for Music”and Observed“National Music Performance and Experimental Teaching Demonstration Center (MPETDC)”

    Institute of Scientific and Technical Information of China (English)

    刘夜

    2016-01-01

    “The Opening Concert of the 10th Chinese Golden Bell Award for Music”performed by Wuhan Conservatory of Music (WCM) in Guangzhou Opera House on the evening of November 18, 2015. This paper reviewed and observed the concert, ex-pounded“a group of generous Hubei local original music”,“the individual version of Erhu and symphony Horse Race and Spring Water of Er Quan Reflect the Moon”,“lively music dialogue between China and foreign”, as well as the platform of artistic practice of WCM, the“National Music Performance and Experimental Teaching Dem-onstration Center (MPETDC).%武汉音乐学院承办演出的“第十届中国音乐金钟奖开幕式音乐会”,于2015年11月18日晚在广州大剧院上演。文章分别从音乐会中“一组厚重的湖北本土原创音乐”、“《赛马》《二泉映月》独特的二胡与交响乐版本”、“生动的中外音乐对话”兼及该院艺术实践的亮丽平台“国家级音乐表演实验教学示范中心”展开评述与观察。

  19. My Experience In the Cherished Class of Bredel%布伦德尔给我上的宝贵一课

    Institute of Scientific and Technical Information of China (English)

    肖荻

    2006-01-01

    今年五月,我在英国第二大城市——伯明翰角逐Symphonv hall Prize.这是每年一度的混合器乐比赛,竞争很激烈,冠军除得到奖金外还可获得在Symphony hall开独奏会的机会,那是个可容纳3000人的非常漂亮的音乐厅,也是世界杰出艺术大师们献岂的舞台、经过几轮混战,我赢来了最终的胜利,6月21日.作为获奖者我有幸以嘉宾的身份参加了布伦德尔(A.Brendel)先生在该音乐厅举行的音乐会,并在著名乐评家、Symphonv hall剧院经理约翰·詹金斯(Lydon Jenkins)先生的热心引荐下得列了和大师会面的机会.

  20. Gadolinium-enhanced MR angiography of the lower extremity arteries with an automated table-feed technique

    International Nuclear Information System (INIS)

    Purpose: To evaluate contrast enhanced magnetic resonance angiography (ceMRA) with an automated table-feed technique in patients with arterio-occlusive disease for imaging of the pelvic and peripheral arteries. Methods: Twenty-two patients underwent three-dimensional gadolinium-enhanced MR angio-graphy in a three-step automatic table-feed technique on a Magnetom Symphony operating at 1.5 Tesla. Maximum intensity projection images (MIP) were generated from the subtracted and original studies. Image quality and venous contrast were evaluated by two groups of observers. 304 vessels (17 patients) were compared with DSA as the standard of reference. Results: All examinations were performed without any technical problems. Diagnostic quality of the MIP of subtracted data sets was superior to that of the unsubtracted images. Venous overlay was 61% in the lower leg. In a total of 599 observations, a sensitivity of 96% (95%, 82%) and a specificity of 87% (88%, 99%) were high compared to DSA in the detection of significant stenoses ≥50% (≥75%, occlusions). Interobserver correlation was good (linear correlation 0.9). Conclusion: Stepping-table digital subtraction contrast enhanced MRA is a promising technique in the diagnosis of peripheral arterio-occlusive disease. (orig.)