WorldWideScience

Sample records for bk020014 pall bds

  1. El Test BDS: Posibles Limitaciones

    Directory of Open Access Journals (Sweden)

    Sanz Carnero, Basilio

    2001-01-01

    Full Text Available El test BDS (1987 ha alcanzado un nivel de uso tan elevado que ha sido primeramente publicado en 1996, y, finalmente, elevado a formar parte de uno de los test que incorpora el difundido paquete informático conocido como E-views, en particular, en el caso de la última versión (Versión 4.0. Anticipándonos a lo que esto puede suponer, pretendemos asentar con la mayor claridad y simplicidad posible, los cometidos fundamentales del test BDS. En primer lugar, pretendemos en esta nota mostrar sus fundamentos, y sus limitaciones. Apuntamos, igualmente, algún atractor no detectado por el test, así como el uso sistemático y detallado del proceso a seguir para ejecutar el test. A lo largo del trabajo se exponen algunos criterios de elección de los parámetros principales. Las conclusiones fundamentales son, por un lado, que no es un test de caos determinista, y por otro, que es un test con poder para detectar estructura no lineal, tanto determinista como estocástica. Finalmente, se dan los resultados de aplicar el test original a varios atractores caóticos suficientemente conocidos.

  2. Measurement of B(Ds -> munu)

    CERN Document Server

    Abe, K; Aihara, H; Arinstein, K; Aso, T; Aulchenko, V; Aushev, T; Aziz, T; Bahinipati, S; Bakich, A M; Balagura, V; Ban, Y; Banerjee, S; Barberio, E; Bay, A; Bedny, I; Belous, K S; Bhardwaj, V; Bitenc, U; Blyth, S; Bondar, A; Bozek, A; Bracko, M; Brodzicka, J; Browder, T E; Chang, M C; Chang, P; Chao, Y; Chen, A; Chen, K F; Chen, W T; Cheon, B G; Chiang, C C; Chistov, R; Cho, I S; Choi, S K; Choi, Y; Choi, Y K; Cole, S; Dalseno, J; Danilov, M; Das, A; Dash, M; Dragic, J; Drutskoy, A; Eidelman, S; Epifanov, D; Fratina, S; Fujii, H; Fujikawa, M; Gabyshev, N; Garmash, A; Go, A; Gokhroo, G; Goldenzweig, P; Golob, B; Grosse-Perdekamp, M; Guler, H; Ha, H; Haba, J; Hara, K; Hara, T; Hasegawa, Y; Hastings, N C; Hayasaka, K; Hayashii, H; Hazumi, M; Heffernan, D; Higuchi, T; Hinz, L; Hoedlmoser, H; Hokuue, T; Horii, Y; Hoshi, Y; Hoshina, K; Hou, S; Hou, W S; Hsiung, Y B; Hyun, H J; Igarashi, Y; Iijima, T; Ikado, K; Inami, K; Ishikawa, A; Ishino, H; Itoh, R; Iwabuchi, M; Iwasaki, M; Iwasaki, Y; Jacoby, C; Joshi, N J; Kaga, M; Kah, D H; Kaji, H; Kajiwara, S; Kakuno, H; Kang, J H; Kapusta, P; Kataoka, S U; Katayama, N; Kawai, H; Kawasaki, T; Kibayashi, A; Kichimi, H; Kim, H J; Kim, H O; Kim, J H; Kim, S K; Kim, Y J; Kinoshita, K; Korpar, S; Kozakai, Y; Krizan, P; Krokovny, P; Kumar, R; Kurihara, E; Kusaka, A; Kuzmin, A; Kwon, Y J; Lange, J S; Leder, G; Lee, J; Lee, J S; Lee, M J; Lee, S E; Lesiak, T; Li, J; Limosani, A; Lin, S W; Liu, Y; Liventsev, D; MacNaughton, J; Majumder, G; Mandl, F; Marlow, D; Matsumura, T; Matyja, A; McOnie, S; Medvedeva, T; Mikami, Y; Mitaroff, W A; Miyabayashi, K; Miyake, H; Miyata, H; Miyazaki, Y; Mizuk, R; Moloney, G R; Mori, T; Müller, J; Murakami, A; Nagamine, T; Nagasaka, Y; Nakahama, Y; Nakamura, I; Nakano, E; Nakao, M; Nakayama, H; Nakazawa, H; Natkaniec, Z; Neichi, K; Nishida, S; Nishimura, K; Nishio, Y; Nishizawa, I; Nitoh, O; Noguchi, S; Nozaki, T; Ogawa, A; Ogawa, S; Ohshima, T; Okuno, S; Olsen, S L; Ono, S; Ostrowicz, W; Ozaki, H; Pakhlov, P; Pakhlova, G; Palka, H; Park, C W; Park, H; Park, K S; Parslow, N; Peak, L S; Pernicka, M; Pestotnik, R; Peters, M; Piilonen, L E; Poluektov, A; Rorie, J; Rózanska, M; Sahoo, H; Sakai, Y; Sakaue, H; Sasao, N; Sarangi, T R; Satoyama, N; Sayeed, K; Schietinger, T; Schneider, O; Schonmeier, P; Schümann, J; Schwanda, C; Schwartz, A J; Seidl, R; Sekiya, A; Senyo, K; Sevior, M E; Shang, L; Shapkin, M; Shen, C P; Shibuya, H; Shinomiya, S; Shiu, J G; Shwartz, B; Singh, J B; Sokolov, A; Solovieva, E; Somov, A; Stanic, S; Staric, M; Stypula, J; Sugiyama, A; Sumisawa, K; Sumiyoshi, T; Suzuki, S; Suzuki, S Y; Tajima, O; Takasaki, F; Tamai, K; Tamura, N; Tanaka, M; Taniguchi, N; Taylor, G N; Teramoto, Y; Tikhomirov, I; Trabelsi, K; Tse, Y F; Tsuboyama, T; Uchida, K; Uchida, Y; Uehara, S; Ueno, K; Uglov, T; Unno, Y; Uno, S; Urquijo, P; Ushiroda, Y; Usov, Yu; Varner, G; Varvell, K E; Vervink, K; Villa, S; Vinokurova, A; Wang, C C; Wang, C H; Wang, J; Wang, M Z; Wang, P; Wang, X L; Watanabe, M; Watanabe, Y; Wedd, R; Wicht, J; Widhalm, L; Wiechczynski, J; Won, E; Yabsley, B D; Yamaguchi, A; Yamamoto, H; Yamaoka, M; Yamashita, Y; Yamauchi, M; Yuan, C Z; Yusa, Y; Zhang, C C; Zhang, L M; Zhang, Z P; Zhilich, V; Zhulanov, V; Zupanc, A; Zwahlen, N

    2007-01-01

    We present preliminary results for the branching fraction B(Ds -> munu) using a 548 fb^-1 data sample collected by the Belle experiment at the KEKB e+e- collider. The Ds momentum is determined by full reconstruction of the recoil system in events of the type e+e- -> D*sDKX, D*s -> Ds gamma where X is any number of additional pions or photons from fragmentation. The full reconstruction method provides high resolution in the neutrino momentum and thus good background separation, equivalent to that reached at experiments at the tau-charm factories such as CLEO-c or BES. We obtain the preliminary branching fraction B(Ds -> munu) = (6.44 +- 0.76 (stat) +- 0.52 (syst)) x 10^(-3), implying a Ds decay constant of f_Ds = 275 +- 16 (stat) +- 12 (syst) MeV.

  3. The ISS Sensitizing Agents Data Bank (BDS).

    Science.gov (United States)

    Brunetto, Barbara; Binetti, Roberto; Ceccarelli, Federica; Costamagna, Francesca Marina; D'Angiolini, Antonella; Fabri, Alessandra; Ferri, Maurizio; Marcello, Ida; Riva, Giovanni; Roazzi, Paolo; Trucchi, Daniela; Tinghino, Raffaella

    2008-01-01

    The Istituto Superiore Sanità has developed a data bank on sensitizing substances (Banca Dati Sensibilizzanti, BDS), available on website (www.iss.it/bdse/), sharing complete, controlled and updated information coming from different sources, such as scientific publications, international agencies and governmental or non governmental organizations. It is worthwhile that the main objective of the BDS is not the classification of sensitizing or potentially sensitizing agents within specific risk classes, but it is essentially to provide concise and non confidential information related to this endpoint. At present, the BDS includes: all the substances officially classified by European Union, (Annex I to Directive 67/548/EEC), some substances listed in I (Directive 67/548/EEC) for endpoints different than "sensitization" but indicated as sensitizers by other relevant institutions, all the substances indicated as sensitizers by relevant agencies or institutions (ACGIH, DFG), some substances indicted as sensitizers by industry and other non-governmental organizations (ETAD and HERA), all the substances regarded as "potentially sensitizing dyes" by the Commission of the European Community for the award of the eco-label to textile products, some substances for which, even in the absence of any categorization by Union, ACGIH or DFG, it is not possible to exclude a sensitizing potential on the basis of reliable documents.

  4. Contribution Analysis of BDS/GPS Combined Orbit Determination

    Science.gov (United States)

    Zhang, Qin

    2016-07-01

    BeiDou Navigation Satellite System (BDS) does not have the ability of global navigation and positioning currently. The whole tracking observation of satellite orbit and the geometry of reference station are not perfect. These situations influence the accuracy of satellite orbit determination. Based on the theory and method of dynamic orbit determination, the analytical contribution of multi-GNSS combined orbit determination to the solution precision of parameters was derived. And using the measured data, the statistical contribution of BDS/GPS combined orbit determination to the solution precision of orbit and clock error was analyzed. The results show that the contribution of combined orbit determination to the solution precision of the common parameters between different systems was significant. The solution precisions of the orbit and clock error were significantly improved except GEO satellites. The statistical contribution of BDS/GPS combined orbit determination to the precision of BDS satellite orbit, the RMS of BDS satellite clock error and the RMS of receiver clock error were 36.21%, 26.88% and 20.88% respectively. Especially, the contribution to the clock error of receivers which were in the area with few visible satellites was particularly significant. And the statistical contribution was 45.95%.

  5. The PPP Precision Analysis Based on BDS Regional Navigation System

    Directory of Open Access Journals (Sweden)

    ZHU Yongxing

    2015-04-01

    Full Text Available BeiDou navigation satellite system(BDS has opened service in most of the Asia-Pacific region, it offers the possibility to break the technological monopoly of GPS in the field of high-precision applications, so its performance of precise point positioning (PPP has been a great concern. Firstly, the constellation of BeiDou regional navigation system and BDS/GPS tracking network is introduced. Secondly, the precise ephemeris and clock offset accuracy of BeiDou satellite based on domestic tracking network is analyzed. Finally, the static and kinematic PPP accuracy is studied, and compared with the GPS. The actual measured numerical example shows that the static and kinematic PPP based on BDS can achieve centimeter-level and decimeter-level respectively, reaching the current level of GPS precise point positioning.

  6. Design method for Pall-BRB frictional damping brace system%新型Pall-BRB摩擦阻尼支撑体系设计方法

    Institute of Scientific and Technical Information of China (English)

    张纪刚; 欧进萍

    2011-01-01

    Based on the geometry nonlinearity,the hysteretic behavior of a new-typed Pall-BRB frictional damping brace system,whose braces are buckling restrained braces(BRB) instead of conventional common Pall-typed frictional damper(PFD) braces,is analyzed using ANSYS finite element software.The hysteretic behavior of Pall-BRB frictional damping brace system is compared with the common PFD brace system.The analytical results show that the buckling restrained braces can reach tension and compression,and the ultimate compression and tension strengths are almost the same,and the energy dissipation is very good.At the same time,the influence of BRB′s stiffness,slip force of the Pall-typed damper,the size of damper and the elevation angle of BRB on hysteretic of system and tension force is analyzed.The results show that the Pall-BRB brace system has better energy dissipation than original Pall brace system,the tension force of the BRBs can keep constant;the maximum tension force of BRBs has relationship with slip force of damper,and the greater the slip force of damper is,the greater the energy dissipation is,and the BRBs can act fully.Finally,a simple design method of Pall-BRB frictional damping brace system is proposed.%考虑几何非线性采用ANSYS有限元软件对一种新型Pall-BRB摩擦阻尼支撑体系(采用防屈曲支撑(BRB)代替Pall型摩擦阻尼器(PFD)的普通支撑)的滞回特性进行分析.首先进行了Pall型普通支撑体系和Pall-BRB摩擦阻尼支撑体系的滞回性能对比分析,结果表明,防屈曲支撑在拉压循环荷载作用下均能达到屈服,拉压承载力基本一致,耗能能力优于普通支撑.然后分析了防屈曲支撑刚度、Pall型阻尼器起滑摩擦力、阻尼器的大小以及防屈曲支撑与水平方向的倾角等因素对体系滞回特性以及支撑内力的影响.结果表明,Pall-

  7. Glacial Refugium of Pinus pumila (Pall.) Regel in Northeastern Siberia

    Energy Technology Data Exchange (ETDEWEB)

    Shilo, N A; Lozhkin, A V; Anderson, P M; Brown, T A; Pakhomov, A Y; Solomatkina, T B

    2007-02-10

    One of the most glowing representatives of the Kolyma flora [1], ''Pinus pumila'' (Pall.) Regel (Japanese stone pine), is a typical shrub in larch forests of the northern Okhotsk region, basins of the Kolyma and Indigirka rivers, and high-shrub tundra of the Chukchi Peninsula. It also forms a pine belt in mountains above the forest boundary, which gives way to the grass-underbrush mountain tundra and bald mountains. In the southern Chukchi Peninsula, ''Pinus pumila'' along with ''Duschekia fruticosa'' (Rupr.) Pouzar and ''Betula middendorffii'' Trautv. et C. A. Mey form trailing forests transitional between tundra and taiga [2]. Pinus pumila pollen, usually predominating in subfossil spore-and-pollen spectra of northeastern Siberia, is found as single grains or a subordinate component (up 2-3%, rarely 10%) in spectra of lacustrine deposits formed during the last glacial stage (isotope stage 2) in the Preboreal and Boreal times of the Holocene. Sometimes, its content increases to 15-22% in spectra of lacustrine deposits synchronous to the last glacial stage near the northern coast of the Sea of Okhotsk [3], evidently indicating the proximity of Japanese stone pine thickets.

  8. Discontinuities of BFKL amplitudes and the BDS ansatz

    Science.gov (United States)

    Fadin, V. S.; Fiore, R.

    2015-12-01

    We perform an examination of discontinuities of multiple production amplitudes, which are required for further development of the BFKL approach. It turns out that the discontinuities of 2 → 2 + n amplitudes obtained in the BFKL approach contradict to the BDS ansatz for amplitudes with maximal helicity violation in N = 4 supersymmetric Yang-Mills theory with large number of colors starting with n = 2. Explicit expressions for the discontinuities of the 2 → 3 and 2 → 4 amplitudes in the invariant mass of pairs of produced gluons are obtained in the planar N = 4 SYM in the next-to-leading logarithmic approximation. These expressions can be used for checking the conjectured duality between the light-like Wilson loops and the MHV amplitudes.

  9. Improving Ambiguity Resolution for Medium Baselines Using Combined GPS and BDS Dual/Triple-Frequency Observations

    Directory of Open Access Journals (Sweden)

    Wang Gao

    2015-10-01

    Full Text Available The regional constellation of the BeiDou navigation satellite system (BDS has been providing continuous positioning, navigation and timing services since 27 December 2012, covering China and the surrounding area. Real-time kinematic (RTK positioning with combined BDS and GPS observations is feasible. Besides, all satellites of BDS can transmit triple-frequency signals. Using the advantages of multi-pseudorange and carrier observations from multi-systems and multi-frequencies is expected to be of much benefit for ambiguity resolution (AR. We propose an integrated AR strategy for medium baselines by using the combined GPS and BDS dual/triple-frequency observations. In the method, firstly the extra-wide-lane (EWL ambiguities of triple-frequency system, i.e., BDS, are determined first. Then the dual-frequency WL ambiguities of BDS and GPS were resolved with the geometry-based model by using the BDS ambiguity-fixed EWL observations. After that, basic (i.e., L1/L2 or B1/B2 ambiguities of BDS and GPS are estimated together with the so-called ionosphere-constrained model, where the ambiguity-fixed WL observations are added to enhance the model strength. During both of the WL and basic AR, a partial ambiguity fixing (PAF strategy is adopted to weaken the negative influence of new-rising or low-elevation satellites. Experiments were conducted and presented, in which the GPS/BDS dual/triple-frequency data were collected in Nanjing and Zhengzhou of China, with the baseline distance varying from about 28.6 to 51.9 km. The results indicate that, compared to the single triple-frequency BDS system, the combined system can significantly enhance the AR model strength, and thus improve AR performance for medium baselines with a 75.7% reduction of initialization time on average. Besides, more accurate and stable positioning results can also be derived by using the combined GPS/BDS system.

  10. Modeling and Assessment of GPS/BDS Combined Precise Point Positioning

    Science.gov (United States)

    Chen, Junping; Wang, Jungang; Zhang, Yize; Yang, Sainan; Chen, Qian; Gong, Xiuqiang

    2016-01-01

    Precise Point Positioning (PPP) technique enables stand-alone receivers to obtain cm-level positioning accuracy. Observations from multi-GNSS systems can augment users with improved positioning accuracy, reliability and availability. In this paper, we present and evaluate the GPS/BDS combined PPP models, including the traditional model and a simplified model, where the inter-system bias (ISB) is treated in different way. To evaluate the performance of combined GPS/BDS PPP, kinematic and static PPP positions are compared to the IGS daily estimates, where 1 month GPS/BDS data of 11 IGS Multi-GNSS Experiment (MGEX) stations are used. The results indicate apparent improvement of GPS/BDS combined PPP solutions in both static and kinematic cases, where much smaller standard deviations are presented in the magnitude distribution of coordinates RMS statistics. Comparisons between the traditional and simplified combined PPP models show no difference in coordinate estimations, and the inter system biases between the GPS/BDS system are assimilated into receiver clock, ambiguities and pseudo-range residuals accordingly. PMID:27455278

  11. Modeling and Assessment of GPS/BDS Combined Precise Point Positioning.

    Science.gov (United States)

    Chen, Junping; Wang, Jungang; Zhang, Yize; Yang, Sainan; Chen, Qian; Gong, Xiuqiang

    2016-07-22

    Precise Point Positioning (PPP) technique enables stand-alone receivers to obtain cm-level positioning accuracy. Observations from multi-GNSS systems can augment users with improved positioning accuracy, reliability and availability. In this paper, we present and evaluate the GPS/BDS combined PPP models, including the traditional model and a simplified model, where the inter-system bias (ISB) is treated in different way. To evaluate the performance of combined GPS/BDS PPP, kinematic and static PPP positions are compared to the IGS daily estimates, where 1 month GPS/BDS data of 11 IGS Multi-GNSS Experiment (MGEX) stations are used. The results indicate apparent improvement of GPS/BDS combined PPP solutions in both static and kinematic cases, where much smaller standard deviations are presented in the magnitude distribution of coordinates RMS statistics. Comparisons between the traditional and simplified combined PPP models show no difference in coordinate estimations, and the inter system biases between the GPS/BDS system are assimilated into receiver clock, ambiguities and pseudo-range residuals accordingly.

  12. Modeling and Assessment of GPS/BDS Combined Precise Point Positioning.

    Science.gov (United States)

    Chen, Junping; Wang, Jungang; Zhang, Yize; Yang, Sainan; Chen, Qian; Gong, Xiuqiang

    2016-01-01

    Precise Point Positioning (PPP) technique enables stand-alone receivers to obtain cm-level positioning accuracy. Observations from multi-GNSS systems can augment users with improved positioning accuracy, reliability and availability. In this paper, we present and evaluate the GPS/BDS combined PPP models, including the traditional model and a simplified model, where the inter-system bias (ISB) is treated in different way. To evaluate the performance of combined GPS/BDS PPP, kinematic and static PPP positions are compared to the IGS daily estimates, where 1 month GPS/BDS data of 11 IGS Multi-GNSS Experiment (MGEX) stations are used. The results indicate apparent improvement of GPS/BDS combined PPP solutions in both static and kinematic cases, where much smaller standard deviations are presented in the magnitude distribution of coordinates RMS statistics. Comparisons between the traditional and simplified combined PPP models show no difference in coordinate estimations, and the inter system biases between the GPS/BDS system are assimilated into receiver clock, ambiguities and pseudo-range residuals accordingly. PMID:27455278

  13. The Proposal of a BDS Syllabus Framework to Suit Choice Based Credit System (CBCS)

    Science.gov (United States)

    Sethuraman, KR; Narayan, KA

    2016-01-01

    Introduction Higher education takes a new dimension universally in the form of choice based Credit System (CBCS). In India, the University Grants Commission (UGC) has made CBCS mandatory in all fields except for Health Profession. Not much attempts were made in designing a BDS syllabus to suit CBCS. Aim Aim of the study was to propose a model dental syllabus to fit into choice based credit system. Materials and Methods A model BDS syllabus Prototype for CBCS was designed based on the UGC guidelines for terms as well as calculations for CBCS. Engineering curriculum models from IIT and Anna University were also referred to. Results Semester based BDS syllabus was designed without changing the norms of Dental Council of India (DCI). All the must know areas of the subjects were considered as “core” areas and the desirable and nice to know areas are left for “electives” by the students. By this method, none of the subject was left out at the same time students are provided with electives to learn deeper on their topics of choice. Conclusion The existing BDS syllabus can be effectively modified by incorporating few changes based on the UGC regulations for Choice based credit system. The proposed framework gives an insight on the nature of modifications that are needed. By adopting this, BDS Course regulations can also follow CBCS without neglecting or reducing the weightage of any subject. PMID:27656467

  14. BDS/GPS Dual Systems Positioning Based on the Modified SR-UKF Algorithm.

    Science.gov (United States)

    Kong, JaeHyok; Mao, Xuchu; Li, Shaoyuan

    2016-01-01

    The Global Navigation Satellite System can provide all-day three-dimensional position and speed information. Currently, only using the single navigation system cannot satisfy the requirements of the system's reliability and integrity. In order to improve the reliability and stability of the satellite navigation system, the positioning method by BDS and GPS navigation system is presented, the measurement model and the state model are described. Furthermore, the modified square-root Unscented Kalman Filter (SR-UKF) algorithm is employed in BDS and GPS conditions, and analysis of single system/multi-system positioning has been carried out, respectively. The experimental results are compared with the traditional estimation results, which show that the proposed method can perform highly-precise positioning. Especially when the number of satellites is not adequate enough, the proposed method combine BDS and GPS systems to achieve a higher positioning precision. PMID:27153068

  15. BDS/GPS Dual Systems Positioning Based on the Modified SR-UKF Algorithm

    Science.gov (United States)

    Kong, JaeHyok; Mao, Xuchu; Li, Shaoyuan

    2016-01-01

    The Global Navigation Satellite System can provide all-day three-dimensional position and speed information. Currently, only using the single navigation system cannot satisfy the requirements of the system’s reliability and integrity. In order to improve the reliability and stability of the satellite navigation system, the positioning method by BDS and GPS navigation system is presented, the measurement model and the state model are described. Furthermore, the modified square-root Unscented Kalman Filter (SR-UKF) algorithm is employed in BDS and GPS conditions, and analysis of single system/multi-system positioning has been carried out, respectively. The experimental results are compared with the traditional estimation results, which show that the proposed method can perform highly-precise positioning. Especially when the number of satellites is not adequate enough, the proposed method combine BDS and GPS systems to achieve a higher positioning precision. PMID:27153068

  16. BDS/GPS Dual Systems Positioning Based on the Modified SR-UKF Algorithm

    Directory of Open Access Journals (Sweden)

    JaeHyok Kong

    2016-05-01

    Full Text Available The Global Navigation Satellite System can provide all-day three-dimensional position and speed information. Currently, only using the single navigation system cannot satisfy the requirements of the system’s reliability and integrity. In order to improve the reliability and stability of the satellite navigation system, the positioning method by BDS and GPS navigation system is presented, the measurement model and the state model are described. Furthermore, the modified square-root Unscented Kalman Filter (SR-UKF algorithm is employed in BDS and GPS conditions, and analysis of single system/multi-system positioning has been carried out, respectively. The experimental results are compared with the traditional estimation results, which show that the proposed method can perform highly-precise positioning. Especially when the number of satellites is not adequate enough, the proposed method combine BDS and GPS systems to achieve a higher positioning precision.

  17. BDS/GPS Dual Systems Positioning Based on the Modified SR-UKF Algorithm.

    Science.gov (United States)

    Kong, JaeHyok; Mao, Xuchu; Li, Shaoyuan

    2016-05-03

    The Global Navigation Satellite System can provide all-day three-dimensional position and speed information. Currently, only using the single navigation system cannot satisfy the requirements of the system's reliability and integrity. In order to improve the reliability and stability of the satellite navigation system, the positioning method by BDS and GPS navigation system is presented, the measurement model and the state model are described. Furthermore, the modified square-root Unscented Kalman Filter (SR-UKF) algorithm is employed in BDS and GPS conditions, and analysis of single system/multi-system positioning has been carried out, respectively. The experimental results are compared with the traditional estimation results, which show that the proposed method can perform highly-precise positioning. Especially when the number of satellites is not adequate enough, the proposed method combine BDS and GPS systems to achieve a higher positioning precision.

  18. Convergence Time and Positioning Accuracy Comparison between BDS and GPS Precise Point Positioning

    Directory of Open Access Journals (Sweden)

    ZHANG Xiaohong

    2015-03-01

    Full Text Available BDS/GPS data from MGEX were processed by TriP 2.0 software developed at Wuhan University. Both static and kinematic float PPP are tested by adopting precise satellite orbits and clocks provided by Research Center of GNSS, Wuhan University. The results show that the convergence time of BDS static PPP is about 80min while kinematic PPP is about 100min. For 3h observations, static positioning accuracy of 5 cm and kinematic positioning accuracy of 8 cm in horizontal, about 12 cm in vertical can be achieved. Similar to GPS PPP, precision in east component is worse than north. At present, BDS PPP needs longer convergence time than GPS PPP to reach an absolute positioning accuracy of cm~dm due to the lack of global tracking stations and the limited accuracy of orbit and clock products.

  19. The hexagon Wilson loop and the BDS ansatz for the six-gluon amplitude

    OpenAIRE

    Drummond, J M; Henn, J.; Korchemsky, G.P.; Sokatchev, E.

    2007-01-01

    As a test of the gluon scattering amplitude/Wilson loop duality, we evaluate the hexagonal light-like Wilson loop at two loops in N=4 super Yang-Mills theory. We compare its finite part to the Bern-Dixon-Smirnov (BDS) conjecture for the finite part of the six-gluon amplitude. We find that the two expressions have the same behavior in the collinear limit, but they differ by a non-trivial function of the three (dual) conformally invariant variables. This implies that either the BDS conjecture o...

  20. Precise orbit determination of Multi-GNSS constellation including GPS GLONASS BDS and GALIEO

    Science.gov (United States)

    Dai, Xiaolei

    2014-05-01

    In addition to the existing American global positioning system (GPS) and the Russian global navigation satellite system (GLONASS), the new generation of GNSS is emerging and developing, such as the Chinese BeiDou satellite navigation system (BDS) and the European GALILEO system. Multi-constellation is expected to contribute to more accurate and reliable positioning and navigation service. However, the application of multi-constellation challenges the traditional precise orbit determination (POD) strategy that was designed usually for single constellation. In this contribution, we exploit a more rigorous multi-constellation POD strategy for the ongoing IGS multi-GNSS experiment (MGEX) where the common parameters are identical for each system, and the frequency- and system-specified parameters are employed to account for the inter-frequency and inter-system biases. Since the authorized BDS attitude model is not yet released, different BDS attitude model are implemented and their impact on orbit accuracy are studied. The proposed POD strategy was implemented in the PANDA (Position and Navigation Data Analyst) software and can process observations from GPS, GLONASS, BDS and GALILEO together. The strategy is evaluated with the multi-constellation observations from about 90 MGEX stations and BDS observations from the BeiDou experimental tracking network (BETN) of Wuhan University (WHU). Of all the MGEX stations, 28 stations record BDS observation, and about 80 stations record GALILEO observations. All these data were processed together in our software, resulting in the multi-constellation POD solutions. We assessed the orbit accuracy for GPS and GLONASS by comparing our solutions with the IGS final orbit, and for BDS and GALILEO by overlapping our daily orbit solution. The stability of inter-frequency bias of GLONASS and inter-system biases w.r.t. GPS for GLONASS, BDS and GALILEO were investigated. At last, we carried out precise point positioning (PPP) using the multi

  1. An Accurate Method for the BDS Receiver DCB Estimation in a Regional Network

    Directory of Open Access Journals (Sweden)

    LI Xin

    2016-08-01

    Full Text Available An accurate approach for receiver differential code biases (DCB estimation is proposed with the BDS data obtained from a regional tracking network. In contrast to the conventional methods for BDS receiver DCB estimation, the proposed method does not require a complicated ionosphere model, as long as one reference station receiver DCB is known. The main idea for this method is that the ionosphere delay is highly dependent on the geometric ranges between the BDS satellite and the receiver normally. Therefore, the non-reference station receivers DCBs in this regional area can be estimated using single difference (SD with reference stations. The numerical results show that the RMS of these estimated BDS receivers DCBs errors over 30 days are about 0.3 ns. Additionally, after deduction of these estimated receivers DCBs and knowing satellites DCBs, the extractive diurnal VTEC showed a good agreement with the diurnal VTEC gained from the GIM interpolation, indicating the reliability of the estimated receivers DCBs.

  2. The BDS iGMAS RIOS station at Observatório Nacional, Rio de Janeiro

    Science.gov (United States)

    Humberto Andrei, Alexandre; Song, Shuli; Junqueira, Selma; Beauvalet, Laurene

    2016-07-01

    GNSS navigation satellites are currently being developed by all major players in the science and technology scene, to compete with the GPS system. Because their applications span many different areas, from traffic and cargo control, to geodesy and seismic monitoring, it is required to assess the coherence between the different constellations. BDS is the GNSS system currently developed in China. Its first generation of satellites consisted of 3 geostationnary satellites allowing geolocalisation in China only. In addition to these satellites, other satellites have been launched in geostationnary and geosynchronous orbits, as well as satellites orbiting with a classical GNSS semi-major axis. With these additions, the BDS system possesses 19 operating satellites, and though the system is mostly efficient for geolocalisation in Asia, the satellites are also visible in other parts of the globe. In parallel to the development of the BDS constellation, China has launched the iGMAS (International GNSS Monitoring and Assessment Service) project to develop a global tracking network of multi-GNSS geodetic receivers. One of the goals of this project is to evaluate the efficiency of the BDS constellation as well as the efficiency of the receivers developed by the Chinese laboratories. As part of the Brazilian program COSBAN leaded by the Foreign Affairs Ministry to foster up the science and technology partnership with China, materialized by the collaboration between the Shanghai Astronomical Observatory/CAS and the Observatório Nacional/MCTI, in Rio de Janeiro. Through it the RIOS-iGMAS station was installed at Observatório Nacional, where the RJEP GNSS station already operates as part of the Brazilian reference system. Thus at the Observatório Nacional can be observed satellites from any constellation with both systems of reception, leading to a direct, efficient way to compare the results obtained for each network. In this communication we focus on the determination of the

  3. SEASONAL AND AGE VARIATIONS OF BERBERINE CONTENT IN INTRODUCED BERBERIS SIBIRICA PALL.

    OpenAIRE

    Иван Васильевич Нечепуренко; Нина Ивановна Комарова; Олег Николаевич Потёмкин; Нариман Фаридович Салахутдинов

    2014-01-01

    The content of isoquinoline alkaloid berberine was studied by means of HPLC in the roots and the above-ground part of introduced Berberis sibirica Pall. of various ages collected during different periods of three vegetative seasons. The roots contain 3–5 times more berberine than the stems. The content of berberine in 7-year-old roots varies slightly during the season; its mean value was 1.10% and maximum content was found in July (1,16±0.03%). The roots of the age of 3 years contain fewer be...

  4. Analysis of Essential Oils from Flower-buds, Leaves and Stems of Filipendula palmata (Pall.) Maxim.

    Institute of Scientific and Technical Information of China (English)

    WU Yin; MENG Xiang-ying; LIU Xiao-hua; BAO Yong-li; WANG Shu-ping; LI Yu-xin

    2005-01-01

    The essential oils of the flower-buds, leaves and stems of Filipendula palmata (Pall.) Maxim. were analyzed by GC and GC-MS. Thirty-three, forty-seven and forty-seven compounds in the flower-buds, leaves and stems were identified, respectively. Methyl salicylate exists in a great amount which is up to 70. 10% in the flower-buds. Its amount is also high in other two parts. The data obtained show that it may be one of the main natural mosquito-expelling and pain-alleviating components in the three parts. The flower-buds are the main active part with the mosquito-expelling function.

  5. Color suppressed contributions to the decay modes B_{d,s} -> D_{s,d} D_{s,d}, B_{d,s} -> D_{s,d} D^*_{s,d}, and B_{d,s} -> D^*_{s,d} D^*_{s,d}

    OpenAIRE

    Eeg, Jan O.; Fajfer, Svjetlana; Prapotnik, Anita

    2005-01-01

    The amplitudes for decays of the type $B_{d,s} \\to D_{s,d} D_{s,d}$, have no factorizable contributions, while $B_{d,s} \\to D_{s,d} D^*_{s,d}$, and $B_{d,s} \\to D^*_{s,d} D^*_{s,d}$ have relatively small factorizable contributions through the annihilation mechanism. The dominant contributions to the decay amplitudes arise from chiral loop contributions and tree level amplitudes which can be obtained in terms of soft gluon emissions forming a gluon condensate. We predict that the branching rat...

  6. Performance Analysis of BDS Satellite Orbits during Eclipse Periods: Results of Satellite Laser Ranging Validation

    Directory of Open Access Journals (Sweden)

    PENG Hanbing

    2016-06-01

    Full Text Available The performance of BeiDou satellite orbits during eclipse periods is an important part of the performance analysis of BeiDou Navigation Satellite System (BDS. Accuracy evaluation of satellite orbits in ephemeris of BDS during eclipse periods can provide support for the service performance assessment. It also helps to find possible deficiencies in the orbit modeling during eclipse periods, which may further contribute to the improvements of functional models for precise orbit determination. The effects of eclipse periods on the orbits of the three types of satellites of BDS are analyzed with the satellite laser ranging (SLR observations ranging from January 2014 to July 2015. At the same time, the orbit radial accuracy of BDS broadcast and precise ephemeris are validated. The results show that, obvious orbit accuracy decrease can be observed in both broadcast and precise ephemeris for IGSO/MEO satellites during eclipse periods (especially the yaw-maneuver periods. And orbit radial errors of IGSO/MEO satellites in broadcast ephemeris reach 1.5~2.0 m, and exceed 10.0 cm for that in precise ephemeris. Performance decrease of the GEO satellite orbit during eclipse arcs can hardly be revealed by the orbit radial residual series. During non-eclipse periods, radial accuracy of IGSO/MEO and GEO satellite orbits in broadcast ephemeris are better than 0.5 m and 0.9 m respectively. The radial accuracy of IGSO/MEO satellite orbits in precise ephemeris are better than 10.0 cm and that of the GEO satellite is about 50.0 cm with a systematic bias of 40.0 cm around.

  7. Analysis and compensation for code Doppler effect of BDS II signal under high dynamics

    Science.gov (United States)

    Ouyang, Xiaofeng; Zeng, Fangling

    2016-01-01

    In high dynamic circumstances, the acquisition of BDS (BeiDou Navigation Satellite System) signal would be affected by the pseudo-code Doppler. The pseudo-code frequency shift is more prominent and complex when BOC modulation has been adopted by BDS-II, but is not yet involved in current compensation algorithm. In addition, the most frequently used code Doppler compensation algorithm is modifying the sampling rate or local bit rate, which not only increases the complexity of the acquisition and tracking, but also is barely realizable for the hardware receiver to modify the local frequency. Therefore, this paper proposes a code Doppler compensation method based on double estimator receiver, which simultaneously controls NCO delay of code tracking loop and subcarrier tracking loop to compensate for pseudo-code frequency shift. The simulation and test are implemented with BDS-II BOC signal. The test results demonstrate that the proposed algorithm can effectively compensate for pseudo-code Doppler of BOC signal and has detection probability 3dB higher than the uncompensated situation when the false alarm rate is under 0.01 and the coherent integration time is 1ms.

  8. Biological consequences of increased natural radiation background for Microtus oeconomus Pall. populations

    Energy Technology Data Exchange (ETDEWEB)

    Kudyasheva, Alevtina G. [Radioecology Department, Institute of Biology, Komi Scientific Center, Ural Division RAS, 28 Kommunisticheskaya ul., Syktyvkar 167982, Komi Republic (Russian Federation); Shishkina, Ludmila N. [Emanuel Institute of Biochemical Physics RAS, Kosygina 4, Moscow 119991 (Russian Federation); Shevchenko, Oksana G. [Radioecology Department, Institute of Biology, Komi Scientific Center, Ural Division RAS, 28 Kommunisticheskaya ul., Syktyvkar 167982, Komi Republic (Russian Federation)], E-mail: shevchenko@ib.komisc.ru; Bashlykova, Ludmila A.; Zagorskaya, Nadezhda G. [Radioecology Department, Institute of Biology, Komi Scientific Center, Ural Division RAS, 28 Kommunisticheskaya ul., Syktyvkar 167982, Komi Republic (Russian Federation)

    2007-09-15

    The results of long-term investigations (1981-1999) on the state of Microtus oeconomus Pall. (tundra vole) population, living under the increased natural radiation background for a long time (for more than 100 generations), are presented. Population density dynamics, morphophysiological parameters, state of the lipid peroxidation regulatory system in different tissues and the cytogenetic effects in bone marrow cells of animals have been analyzed. It is shown that tundra voles from the studied radioactively contaminated areas differ from those on natural radiation background area for the parameters measured. The results of this long-term investigation show that qualitatively new sub-populations of tundra vole on these areas have evolved, which are able to survive in radioactively contaminated environment.

  9. 盐地碱蓬的染色体核型分析%Karyotype analysis of Suaeda salsa (L.) Pall

    Institute of Scientific and Technical Information of China (English)

    张峰; 姚燕

    2013-01-01

    The paper originally analyzes the number of chromosomes and karyotype of Suaeda salsa (L. ) Pall. Results show that its chromosome number is 2n =18, and that its karyotype formula is K(2n) =2x = 18 = 16m +2sm. The karyotype is 1A based on the classification standard of Stebbins.%本文首次对盐地碱蓬(Suaeda salsa(L.)Pall.)的染色体数目和核型进行了分析研究.结果表明,盐地碱蓬的染色体数目2n=18,核型公式为K(2n)=18=16m +2sm.根据Stebbins的核型分类标准,盐地碱蓬的核型属1A型.

  10. Análisis de las deficiencias del test BDS en series temporales univariantes

    Directory of Open Access Journals (Sweden)

    Pedro A. Pérez Pascual

    2002-01-01

    Full Text Available El test BDS de Brock, Dechert y Scheinkman es un test asintótico que proporciona una herramienta no paramétrica para contrastar la hipótesis nula de series i.i.d., con potencia, en teoría, sobre todas las alternativas restantes (lineales y no lineales, estocásticas y deterministas. Recientemente una versión del BDS ha sido implementada en el E-views, motivo por el que la herramienta ganará difusión dentro del análisis econométrico. Desafortunadamente, con anterioridad a esta reciente implementación y aún en la actualidad, se han observado ciertas deficiencias en la potencia y tamaño del test para muestras finitas; la sensibilidad del test ante ciertos parámetros del mismo y en el modo de evaluar los resultados; etc. Estas deficiencias, y otras nuevas, son expuestas y analizadas ofreciendo explicaciones cuando esto es posible.

  11. Alkaloids of Nitraria sibirica Pall. decrease hypertension and albuminuria in angiotensin II-salt hypertension.

    Science.gov (United States)

    Bakri, Mahinur; Yi, Yang; Chen, Ling-Dan; Aisa, Haji Akber; Wang, Mong-Heng

    2014-04-01

    In traditional Chinese medicine, Nitraria sibirica Pall. (Nitrariaceae) is used to treat hypertension. This study determined the effects of the total alkaloids of the leaves of Nitraria sibirica (NSTA) on blood pressure and albuminuria in mice treated with angiotensin II and a high-salt diet (ANG/HS). Adult mice were divided into three groups: control; infused with angiotensin II and fed a diet containing 4% NaCl (ANG/HS; and ANG/HS plus injection of NSTA (1 mg·kg(-1)·d(-1), i.p.). After treatment of these regimens, daily water and food intake, kidney weight, blood pressure, urinary albumin excretion, renal concentrations of inflammatory markers, including soluble intercellular adhesion molecule-1 (sICAM-1) and monocyte chemoattractant protein-1 (MCP-1), and the expression of renal fibrosis markers were determined. Compared to the control group, the ANG/HS group had higher blood pressure and urinary albumin excretion. Treatment with NSTA in ANG/HS mice for three weeks significantly reduced blood pressure and urinary albumin excretion. ANG/HS treatment caused elevated levels of sICAM-1 and MCP-1, as well as increased fibrosis markers. Concurrent treatment with ANG/HS and NSTA attenuated the levels and expression of renal inflammatory and fibrosis markers. Treatment with NSTA effectively reduces hypertension-induced albuminuria through the reduction of renal inflammatory and fibrosis markers. PMID:24863351

  12. Relationship between Major Mineral Nutrient Elements Contents and Flower Colors of Herbaceous Peony (Paeonia Lactiflora Pall.

    Directory of Open Access Journals (Sweden)

    Chengzhong Li

    2015-02-01

    Full Text Available Herbaceous peony (Paeonia lactiflora Pall. is a famous ornamental plant with bright flowers and lush leaves. The flower petal can be used as a fragrant food additive. Understanding the mineral nutrient contents in P. lactiflora is necessary for guiding its cultivation practices as well as its use as a food additive. In this study, we investigated the mineral contents including Calcium (Ca, Potassium (K, Magnesium (Mg, Copper (Cu, iron (Fe and Zinc (Zn in petals and leaves of 20 selected herbaceous peony cultivars in four groups according to their flower colors and the relationship between major mineral nutrient elements contents and flower colors was assessed. In petals, the contents of minerals were in this order K>Ca>Mg>Fe>Zn>Cu; while in leaves were: Ca>K>Mg>Fe>Zn>Cu. Major element contents in petals and leaves among 4 cultivar groups were different at statistically significant levels. Petals in red or purple have higher amount of most major minerals than those in white or pink colors. The wide range of mineral element contents among cultivars is attributed to genotypic variations. The correlations of major mineral elements in the petals and leaves of herbaceous peony cultivars indicate that mineral ions compete for the same absorption sites. The results provided some scientific support for petal nutrition of herbaceous peony and selecting herbaceous peony flowers with dark colors for edible is feasible.

  13. The Root Extract of Gentiana macrophylla Pall. Alleviates Cardiac Apoptosis in Lupus Prone Mice.

    Directory of Open Access Journals (Sweden)

    Chih-Yang Huang

    Full Text Available The roots of the perennial herb Gentiana macrophylla Pall. (GM are known as Qinjiao, which has been used for centuries to treat systemic lupus erythematosus (SLE. However, little is known about the effects of GM on cholesterol-aggravated cardiac abnormalities in SLE, and the mechanisms thereof. This study investigates whether GM exhibits anti-apoptotic effects, focusing on the left ventricle (LV of NZB/W F1 mice fed with high-cholesterol diet. The morphology and apoptotic status of ventricular tissues were determined by microscopy and Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL assay. Levels of apoptotic biomarkers were determined by immunoblotting. The results thus obtained revealed that GM significantly reduced the cholesterol-aggravated apoptosis of LV in NZB/W F1 mice by suppressing both intrinsic and extrinsic apoptotic pathways. Additionally, GM significantly increased the cardiac insulin-like growth factors (IGF-1 survival signaling and anti-apoptotic proteins in LV tissues. Accordingly, GM is considered to be beneficial in alleviating cholesterol-aggravated cardiac damage in SLE, and therefore constitute an alternative treatment for SLE patients with cardiac abnormalities.

  14. Perception of BDS students and fresh graduates about significance of professional ethics in dentistry

    International Nuclear Information System (INIS)

    Objective: To assess the awareness level of undergraduate dentistry students as well as fresh graduates about the significance of professional ethics. Methods: The cross sectional study was conducted among the 3rd, 4th and final year male and female BDS students as well as fresh graduate Interns from the College of Dentistry, King Saud University from January to June 2011. The students were asked to give their opinion about need for applications of professional ethics in dental practice on a five point Likert Scale varying from strongly agree to strongly disagree. Minitab statistical software was used for data analysis. Results: Students at all levels considered professional ethics a very important prerequisite for dental practice with overall mean value of 4.42+-0.36. However, the responses from the senior academic levels were significantly on the higher side compared to those from the junior grades. Generally the religious teachings and spirituality was considered as one of the top most motives for practicing professional ethics in dentistry followed by reputation, financial benefits, fear of punishment and self projection, with overall mean values of 3.93+-0.58, 3.81+-0.49, 3.25+-0.94, 3.21+-1.07 and 3.16+-1.04, respectively. Conclusion: The present findings revealed that Professional Ethics is appreciated by the students as a highly significant factor for their success in dental practice as well as acquiring a good name and position in the society. (author)

  15. LHCb: Measurement of the relative yields of the decay modes $B_{d,s} \\to D^{\\pm}_{(s)}\\pi^{\\mp}$ and $B_{d,s} \\to D^{\\pm}_{(s)} K^{\\pm}$ and determination of $f_d /f_s$ for 7 TeV $pp$ collisions

    CERN Multimedia

    David, P; Morawski, P; Witek, M; Akiba, K; Serra, N; Storaci, B; Tuning, N; Williams, M; Easo, S; Carson, L; Poluektov, A

    2011-01-01

    A fit to the invariant mass distributions is used to determine the relative abundances of the four decay modes $B_{d,s} \\to D^{\\pm}_{(s)}\\pi^{\\mp}$ and $B_{d,s} \\to D^{\\pm}_{(s)} K^{\\mp}$ for $B_{d,s}$ mesons produced in 7 TeV $pp$ collisions at the LHC. From these, the relative branching fractions of the kaon modes with respect to the pion modes, and the value of $f_d /f_s$, are determined.

  16. Study of train positioning method based on BDS/GSM-R co mbination%基于 BDS/GSM-R 组合列车定位方法的研究

    Institute of Scientific and Technical Information of China (English)

    李卫东; 侯丽虹; 王友生

    2016-01-01

    针对卫星定位容易丢失信号的问题,提出北斗卫星导航技术与 GSM-R 技术相结合的定位方法。根据哈尔滨西至长春铁路线的实测数据,利用 BP 神经网络构造 BDS /GSM-R 定位信息的融合模型,采用遗传算法优化 BP 神经的权值和阈值,对比优化前和优化后的 BDS /GSM-R 组合定位方法。实验结果表明:优化后的 BP 神经网络训练结果与列车实际运行轨迹偏差更小,东向、北向、方位角定位误差的波动范围明显减小,可以保持列车定位的连续性和精确性。%Aiming at the problem that satellite positioning signal is easily lost,the positioning method that com-bine BeiDou satellite navigation technology with GSM-R technology was put forward.According to the measured data from the Harbin West railway station to Changchun,onethe BDS /GSM -R positioning information fusion model was firstly built using BP neural network structure.The BP neural weights and thresholds were optimized using genetic algorithm.Finally,the results before and after optimization of combined BDS /GSM-R positioning method was compared..The results show that the difference between the training results of BP neural network after optimization and the practical operation tracks of train is reduced.The range of error located in the east and northoriention and azimuth error are obviously decreased.This method can keep the continuity and precision of train positioning.

  17. An Enhanced Box-Wing Solar Radiation pressure model for BDS and initial results

    Science.gov (United States)

    Zhao, Qunhe; Wang, Xiaoya; Hu, Xiaogong; Guo, Rui; Shang, Lin; Tang, Chengpan; Shao, Fan

    2016-04-01

    Solar radiation pressure forces are the largest non-gravitational perturbations acting on GNSS satellites, which is difficult to be accurately modeled due to the complicated and changing satellite attitude and unknown surface material characteristics. By the end of 2015, there are more than 50 stations of the Multi-GNSS Experiment(MGEX) set-up by the IGS. The simple box-plate model relies on coarse assumptions about the dimensions and optical properties of the satellite due to lack of more detailed information. So, a physical model based on BOX-WING model is developed, which is more sophisticated and more detailed physical structure has been taken into account, then calculating pressure forces according to the geometric relations between light rays and surfaces. All the MGEX stations and IGS core stations had been processed for precise orbit determination tests with GPS and BDS observations. Calculation range covers all the two kinds of Eclipsing and non-eclipsing periods in 2015, and we adopted the un-differential observation mode and more accurate values of satellite phase centers. At first, we tried nine parameters model, and then eliminated the parameters with strong correlation between them, came into being five parameters of the model. Five parameters were estimated, such as solar scale, y-bias, three material coefficients of solar panel, x-axis and z-axis panels. Initial results showed that, in the period of yaw-steering mode, use of Enhanced ADBOXW model results in small improvement for IGSO and MEO satellites, and the Root-Mean-Square(RMS) error value of one-day arc orbit decreased by about 10%~30% except for C08 and C14. The new model mainly improved the along track acceleration, up to 30% while in the radial track was not obvious. The Satellite Laser Ranging(SLR) validation showed, however, that this model had higher prediction accuracy in the period of orbit-normal mode, compared to GFZ multi-GNSS orbit products, as well with relative post

  18. BDS Based on the Uses of the Oceans Icebergs Envisaged for the Service of Mankind%基于 BDS 利用海洋上冰山为人类服务的设想

    Institute of Scientific and Technical Information of China (English)

    郭英起; 范国敏; 刘甫斌; 毕继鑫

    2015-01-01

    The ocean iceberg although called 'Ocean killers',but if humans are able to well prepared in advance ,also can use the tip to the service of humanity .This paper ex‐pounds the ocean iceberg characteristics ,and studied the compass navigation satellite system (BDS) based on the assumption of utilization of marine an iceberg in the service of mankind . The research conclusion can also be for future construction of digital ocean to provide refer‐ence .%海洋上冰山虽然被人们称为“海洋杀手”,但是如果人类能够在远航之前做好充分的准备,亦可以利用冰山为人类服务。本文阐述了海洋上冰山的特点,而且研讨了基于北斗卫星导航系统(BDS )利用海洋上冰山为人类服务的设想。本文研讨的结论也可以为以后数字海洋的建设提供参考。

  19. Ex situ conservation of genetic resources of field elm (Ulmus minor Mill and European white elm (Ulmus laevis Pall

    Directory of Open Access Journals (Sweden)

    Aleksić Jelena

    2004-01-01

    Full Text Available Principles of the conservation of genetic resources of elms (Ulmus spp do not differ fundamentally from the general principles accepted for the conservation of genetic resources of other common Noble Hardwoods. Efficient conservation can best be achieved through appropriate combination of in situ and ex situ methods, which have distinct advantages. Besides that, ex situ conservation is employed when emergency measures are needed for rare endangered populations and when populations are too small to be managed in situ (e.g. risks of genetic drift and inbreeding. The aim of our research is ex situ conservation of genetic resources of field elm {Ulmus minor Mill and European white elm (Ulmus laevis Pall through establishment of field genebanks. Sampling was conducted in one population of field elm and one population of white elm. Plant material (buds from 8 trees of field elm and 10 trees of white elm was used for in vitro production of clones. Obtained clones will be used for establishment of field genebanks on the experimental estate of the Institute of Lowland Forestry and Environment.

  20. Performance analysis on carrier phase-based tightly-coupled GPS/BDS/INS integration in GNSS degraded and denied environments.

    Science.gov (United States)

    Han, Houzeng; Wang, Jian; Wang, Jinling; Tan, Xinglong

    2015-04-14

    The integration of Global Navigation Satellite Systems (GNSS) carrier phases with Inertial Navigation System (INS) measurements is essential to provide accurate and continuous position, velocity and attitude information, however it is necessary to fix ambiguities rapidly and reliably to obtain high accuracy navigation solutions. In this paper, we present the notion of combining the Global Positioning System (GPS), the BeiDou Navigation Satellite System (BDS) and low-cost micro-electro-mechanical sensors (MEMS) inertial systems for reliable navigation. An adaptive multipath factor-based tightly-coupled (TC) GPS/BDS/INS integration algorithm is presented and the overall performance of the integrated system is illustrated. A twenty seven states TC GPS/BDS/INS model is adopted with an extended Kalman filter (EKF), which is carried out by directly fusing ambiguity fixed double-difference (DD) carrier phase measurements with the INS predicted pseudoranges to estimate the error states. The INS-aided integer ambiguity resolution (AR) strategy is developed by using a dynamic model, a two-step estimation procedure is applied with adaptively estimated covariance matrix to further improve the AR performance. A field vehicular test was carried out to demonstrate the positioning performance of the combined system. The results show the TC GPS/BDS/INS system significantly improves the single-epoch AR reliability as compared to that of GPS/BDS-only or single satellite navigation system integrated strategy, especially for high cut-off elevations. The AR performance is also significantly improved for the combined system with adaptive covariance matrix in the presence of low elevation multipath related to the GNSS-only case. A total of fifteen simulated outage tests also show that the time to relock of the GPS/BDS signals is shortened, which improves the system availability. The results also indicate that TC integration system achieves a few centimeters accuracy in positioning based

  1. Performance Analysis on Carrier Phase-Based Tightly-Coupled GPS/BDS/INS Integration in GNSS Degraded and Denied Environments

    Directory of Open Access Journals (Sweden)

    Houzeng Han

    2015-04-01

    Full Text Available The integration of Global Navigation Satellite Systems (GNSS carrier phases with Inertial Navigation System (INS measurements is essential to provide accurate and continuous position, velocity and attitude information, however it is necessary to fix ambiguities rapidly and reliably to obtain high accuracy navigation solutions. In this paper, we present the notion of combining the Global Positioning System (GPS, the BeiDou Navigation Satellite System (BDS and low-cost micro-electro-mechanical sensors (MEMS inertial systems for reliable navigation. An adaptive multipath factor-based tightly-coupled (TC GPS/BDS/INS integration algorithm is presented and the overall performance of the integrated system is illustrated. A twenty seven states TC GPS/BDS/INS model is adopted with an extended Kalman filter (EKF, which is carried out by directly fusing ambiguity fixed double-difference (DD carrier phase measurements with the INS predicted pseudoranges to estimate the error states. The INS-aided integer ambiguity resolution (AR strategy is developed by using a dynamic model, a two-step estimation procedure is applied with adaptively estimated covariance matrix to further improve the AR performance. A field vehicular test was carried out to demonstrate the positioning performance of the combined system. The results show the TC GPS/BDS/INS system significantly improves the single-epoch AR reliability as compared to that of GPS/BDS-only or single satellite navigation system integrated strategy, especially for high cut-off elevations. The AR performance is also significantly improved for the combined system with adaptive covariance matrix in the presence of low elevation multipath related to the GNSS-only case. A total of fifteen simulated outage tests also show that the time to relock of the GPS/BDS signals is shortened, which improves the system availability. The results also indicate that TC integration system achieves a few centimeters accuracy in

  2. Performance analysis on carrier phase-based tightly-coupled GPS/BDS/INS integration in GNSS degraded and denied environments.

    Science.gov (United States)

    Han, Houzeng; Wang, Jian; Wang, Jinling; Tan, Xinglong

    2015-01-01

    The integration of Global Navigation Satellite Systems (GNSS) carrier phases with Inertial Navigation System (INS) measurements is essential to provide accurate and continuous position, velocity and attitude information, however it is necessary to fix ambiguities rapidly and reliably to obtain high accuracy navigation solutions. In this paper, we present the notion of combining the Global Positioning System (GPS), the BeiDou Navigation Satellite System (BDS) and low-cost micro-electro-mechanical sensors (MEMS) inertial systems for reliable navigation. An adaptive multipath factor-based tightly-coupled (TC) GPS/BDS/INS integration algorithm is presented and the overall performance of the integrated system is illustrated. A twenty seven states TC GPS/BDS/INS model is adopted with an extended Kalman filter (EKF), which is carried out by directly fusing ambiguity fixed double-difference (DD) carrier phase measurements with the INS predicted pseudoranges to estimate the error states. The INS-aided integer ambiguity resolution (AR) strategy is developed by using a dynamic model, a two-step estimation procedure is applied with adaptively estimated covariance matrix to further improve the AR performance. A field vehicular test was carried out to demonstrate the positioning performance of the combined system. The results show the TC GPS/BDS/INS system significantly improves the single-epoch AR reliability as compared to that of GPS/BDS-only or single satellite navigation system integrated strategy, especially for high cut-off elevations. The AR performance is also significantly improved for the combined system with adaptive covariance matrix in the presence of low elevation multipath related to the GNSS-only case. A total of fifteen simulated outage tests also show that the time to relock of the GPS/BDS signals is shortened, which improves the system availability. The results also indicate that TC integration system achieves a few centimeters accuracy in positioning based

  3. A geometry-free and ionosphere-free multipath mitigation method for BDS three-frequency ambiguity resolution

    Science.gov (United States)

    Chen, Dezhong; Ye, Shirong; Xia, Jingchao; Liu, Yanyan; Xia, Pengfei

    2016-08-01

    Because of the unknown systematic errors and special satellite constellations in the Beidou system (BDS), it is difficult to quickly and reliably determine the ambiguity over long-range baselines in continuously operating reference station (CORS) network. This study seeks to improve the effectiveness and reliability of BDS ambiguity resolution (AR) by combining the geometry-free and ionosphere-free (GFIF) combination and multipath mitigation algorithm. The GFIF combination composed with three-frequency signals is free of distance-dependent errors and can be used to determine the narrow lane ambiguity. The presence of multipath errors means that not all ambiguities can be correctly achieved by rounding the averaged GFIF ambiguity series. A multipath model of the single-differenced (SD) GFIF combination from the previous period is established for each individual satellite. This model is subtracted from the SD GFIF combination for the current day to remove the effects of multipath errors. Using three triangle networks with lengths of approximately 120, 80 and 50 km, we demonstrate that the proposed method improves the AR performance. The ambiguity averaged first fixing time is typically less than 1801 s for inclined geosynchronous orbit (IGSO) and medium earth orbit (MEO) satellites and less than 2007 s for the ˜ 42° elevation geostationary earth orbit (GEO) C02 satellite. However, it is more time consuming for the low-elevation GEO satellites C04 (˜ 18°) and C05 (˜ 28°). Kalman filtering is used to estimate the troposphere delays and two unfixed ambiguities by employing the ionosphere-free observations of all ambiguity-fixed/unfixed satellites. The experimental results show that only tens of seconds are required for AR in around 90 km baselines.

  4. Correlations Between Foliar Stable Carbon Isotope Composition and Environ-mental Factors in Desert Plant Reaumuria soongorica (Pall.) Maxim.

    Institute of Scientific and Technical Information of China (English)

    Jian-Ying MA; Tuo CHEN; Wei-Ya QIANG; Gang WANG

    2005-01-01

    Leaves of 407 individuals of Reaumuria soongorica (Pall.) Maxim. collected from the major distribution areas were measured to investigate the distribution characteristics of the stable carbon isotope in this desert plant, as well as correlations between δ13C values and environmental factors. Results showed that δ13C values in R. soongorica ranged from-22.77‰. to-29.85‰. and that the mean δ13C value (-26.52‰)was higher than a previously reported δ13C value for a different desert ecosystem. This indicates that R.soongorica belongs to the C3 photosynthetic pathway and has higher water use efficiency than other species. The correlations between δ13C values and environmental factors demonstrated that the foliar δ13C values in R. soongorica increased significantly with decreasing mean annual precipitation and mean relative humidity, and decreased with decreasing duration of sunshine and evaporation. The spatial distribution trend of δ13C values in R. soongorica was not obvious and there was no significant correlation between the δ13C values and mean annual temperature. We conclude that different distribution trends in δ13C values for R. soongorica were likely caused by stomatal limitation rather than by nutrient-related changes in photosynthetic efficiency and that precipitation played an important role in the wide distribution range of R.soongorica. This pattern of δ13C values for R. soongorica reinforced that it is a super-xerophil in terms of its adaptive strategies to a desert environment.

  5. Identification of miRNAs Responsive to Botrytis cinerea in Herbaceous Peony (Paeonia lactiflora Pall. by High-Throughput Sequencing

    Directory of Open Access Journals (Sweden)

    Daqiu Zhao

    2015-09-01

    Full Text Available Herbaceous peony (Paeonia lactiflora Pall., one of the world’s most important ornamental plants, is highly susceptible to Botrytis cinerea, and improving resistance to this pathogenic fungus is a problem yet to be solved. MicroRNAs (miRNAs play an essential role in resistance to B. cinerea, but until now, no studies have been reported concerning miRNAs induction in P. lactiflora. Here, we constructed and sequenced two small RNA (sRNA libraries from two B. cinerea-infected P. lactiflora cultivars (“Zifengyu” and “Dafugui” with significantly different levels of resistance to B. cinerea, using the Illumina HiSeq 2000 platform. From the raw reads generated, 4,592,881 and 5,809,796 sRNAs were obtained, and 280 and 306 miRNAs were identified from “Zifengyu” and “Dafugui”, respectively. A total of 237 conserved and 7 novel sequences of miRNAs were differentially expressed between the two cultivars, and we predicted and annotated their potential target genes. Subsequently, 7 differentially expressed candidate miRNAs were screened according to their target genes annotated in KEGG pathways, and the expression patterns of miRNAs and corresponding target genes were elucidated. We found that miR5254, miR165a-3p, miR3897-3p and miR6450a might be involved in the P. lactiflora response to B. cinerea infection. These results provide insight into the molecular mechanisms responsible for resistance to B. cinerea in P. lactiflora.

  6. Metabolomics coupled with multivariate data and pathway analysis on potential biomarkers in cholestasis and intervention effect of Paeonia lactiflora Pall.

    Directory of Open Access Journals (Sweden)

    Xiao eMa

    2016-02-01

    Full Text Available Background: The dried root of Paeonia lactiflora Pall. (PLP is a classical Chinese herbal medicine that has been used to treat hepatic disease for thousands of years. Our previous work suggested that PLP can be used to treat hepatitis with severe cholestasis. This study explored the mechanism by which PLP affects ANIT-induced cholestasis in rats using a metabolomics approach.Methods: The effects of PLP on serum indices (TBIL, DBIL, AST, ALT, ALP and TBA and the histopathology of the liver were analyzed. Moreover, UHPLC-Q-TOF was performed to identify the possible effect of PLP on metabolites. The pathway analysis was conducted to illustrate the pathways and network by which PLP treats cholestasis. Result: High-dose PLP remarkably down-regulated the serum indices and alleviated histological damage to the liver. Metabolomics analyses showed that the therapeutic effect of high-dose PLP is mainly associated with the regulation of several metabolites, such as glycocholic acid, taurocholic acid, glycochenodeoxycholic acid, L(D-arginine and L-tryptophan. A pathway analysis showed that the metabolites were related to bile acid secretion and amino acid metabolism. In addition, the significant changes in bile acid transporters also indicated that bile acid metabolism might be involved in the therapeutic effect of PLP on cholestasis. Moreover, a principal component analysis indicated that the metabolites in the high-dose PLP group were closer to those of the control, whereas those of the moderate dose or low-dose PLP group were closer to those of the ANIT group. This finding indicated that metabolites may be responsible for the differences between the effects of low-dose and moderate-dose PLP. Conclusions: The therapeutic effect of high-dose PLP on cholestasis is possibly related to regulation of bile acid secretion and amino acid metabolism. Moreover, these findings may help better understand the mechanisms of disease and provide a potential therapy for

  7. 棉团铁线莲中新葡萄糖基萘类成分%A New Glucopyranosyl Naphthalene from Clematis hexapetala Pall

    Institute of Scientific and Technical Information of China (English)

    董彩霞; 史社坡; 赵明波; 屠鹏飞

    2008-01-01

    目的:研究棉团铁线莲(Clematis hexapetala Pall.)的干燥根及根茎的化学成分.方法:利用溶剂提取、硅胶柱色谱和高效液相色谱等技术进行分离、纯化,根据理化性质和波谱数据鉴定化合物的结构.结果:从中分离得到1个葡萄糖基萘类化合物,鉴定为5,8-二氢-6-甲基萘-1,4-二-O-β-D-葡萄糖苷 (1).结论:该化合物为一新化合物,丰富了棉团铁线莲的化学成分.%AIM: To study the chemical constituents of the roots and rhizomes of Clematis hexapetala Pall.. METHODS: The solvent extraction, silica gel column chromatography and pre-HPLC were used to isolate and purify the constituent, and various spectroscopic analyses were used to elucidate the structure. RESULTS: A glucopyranosyl naphthalene (1) derivative, 5,8-dihydro-6-methyl-1,4- β- D -diglucopyranosyl naphthalene has (1) been isolated from this plant. CONCLUSION: This compound is a new one, and this study enriched the chemical constituents of Clematis hexapetala.

  8. Cultivating Erect Milkvetch (Astragalus adsurgens Pall.) (Leguminosae) Improved Soil Properties in Loess Hilly and Gullies in China

    Institute of Scientific and Technical Information of China (English)

    WANG Zhan-bin; WANG Qing-yi

    2013-01-01

    Erect milkvetch (Astragalus adsurgens Pall.), a leguminous grass, is a major source of fuel and forage, and has an important role in the restoration of the degraded ecosystems in central and northeastern China. The objective of this work was to investigate how erect milkvetch planting would affect the physical and chemical properties of soil in degraded arable lands. Soil samples at the depths of 0-20 and 20-40 cm were collected from erect milkvetch planting fileds at ages of 0, 1, 2 and 3 yr. Changes in soil bulk density, soil porosity, total N and P, organic matter content, available P, hydrolysable N and available K were measured. The results showed that root biomass and above-ground plant biomass were both significantly increased with plantation age. The significant increase in root nodule biomass was not observed in the first two years. However, it was significantly increased after three years. Root growth of erect milkvetch improved soil structure, and hence, decreased soil bulk density and increased soil porosity. Furthermore, the nitrogen fixation by erect milkvetch and return of erect milkvetch plant to soil increased the soil total N, hydrolysable N and organic matter content of the soil. Low concentrations of P in the soil with erect milkvetch planting could be ascribed to high plant uptakes and possibly to high sequestrations of P in plant biomass. Concentrations of K significantly increased during the first two years of erect milkvetch planting. The high accumulation of K under erect milkvetch cultivation in the first two years could partly be attributed to low plant uptake, and partly to relatively quick recycling within plant-soil systems. Three years after erect milkvetch plantingr, K accumulation at 0-20 cm soil layer was significantly lower than that from non-vegetated field sites, which could be attributed to high plant uptake. These parameters, except for soil bulk density, were all decreased with increasing soil depth. Soil total N, organic

  9. PHYSICAL REMOVAL OF CRYPTOSPORIDIUM OOCYS, E. COLI, AND BACILLUS SPORES IN DRINKING WATER: PALL CORPORATION MICROZA MICROFILTRATION 3-INCH UNIT, MODEL 4UFD40004-45; AT MANCHESTER, NEW HAMPSHIRE

    Science.gov (United States)

    Verification testing of the Pall Corporation Microza MF S;ystem equipped with a 3-inch filter module, took place between April 30 and August 9, 2000 in Manchester, NH. The source water was drawn from a canal connected to Lake Massabesic, the public reservoir that serves the Town...

  10. Uniform Design for Optimizating Regeneration Shoots Directly from Tender Leaves and Plant Regeneration System of Rhododendron chrysanthum Pall.%基于均匀设计优化牛皮杜鹃嫩叶直接再生芽苗及植株再生体系

    Institute of Scientific and Technical Information of China (English)

    李玉梅; 姜云天; 孙智慧

    2008-01-01

    [Objective] The experimental was aimed to screen the optimum regeneration shoot induction media and rooting media for tender leaves of Rhododendron chrysanthum Pall.[Method] The tender leaves of Rhododendron chrysanthum Pall were taken as explants to select the optimum bud induction media and rooting media through uniform design and the screening results were verified.[Result] The optimum media for regeneration shoot of Rhododendron chrysanthum Pall contained 1/4 MS,3.70 mg/L ZT, 0.02 mg/L IAA and 1.00 mg/L KT and its induction rate was 95.5% and the rooting media contained modified MS, 0.10 mg/L IAA and 0.07 mg/L NAA and its rooting rate was 98%. [Conclusion] Through this experiment, regeneration systems for regeneration shoot and regenerated plant from tender leaves of Rhododendron chrysanthum Pall were created successfully.

  11. 棉团铁线莲总皂甘抗肿瘤作用研究%Antitumor Activities of Total Saponins from Clematis Hexapetala Pall

    Institute of Scientific and Technical Information of China (English)

    杨林; 姚广玉; 薛鸿燕; 杨明俊

    2011-01-01

    Objective:To investigate the antitumor effect of total saponins of Clematis hexapetala Pall.Methods :The total saponins from Clematis hexapetala Pall.were prepared by ethanol extraction and macroporous resin.Its anti - tumor activity in vitro and in vivo was evaluated by MTT colorimetric assay and H22 cells - bearing mice models.Results:The results showed that the total saponins of Clematis hexapetala Pall.significantly inhibited proliferation of the human hepatoma cell lines HepG2, SMMC -7721 and the human cervical carcinoma cell Hela at the concentration of 0.1 -1mg·mL-1.The IC50 value on these three tumor cells were 0.5298mg·mL-1 ,0.2047mg·mL-1 and 0.2877mg·mL-1 respectively.In vivo, high ( 1.5 g· kg - 1 ), middle ( 0.75 g· kg - 1 ) and low (0.375 g· kg - 1 ) dose total saponins of Clematis hexapetala Pall.also significantly suppressed the tumor growth with tumor inhibition rate of 41.55% ,34.96% and 32.37%respectively.The slice through the pathological observation of tumor tissue also indicated that it has good antitumor activity.However, it can also reduce the spleen index and displays certain inhibitory action to the immune organ of tumor -bearing mice.Conclusion:The total saponins from Clematis hexapetala Pall.has a significant antitumor effect, but it also can suppress immune function of experimentals animals in vivo.%目的:研究棉团铁线莲总皂苷的体内外抗肿瘤作用.方法:采用乙醇提取、大孔树脂除糖的方法制备棉团铁线莲总皂苷,以MTT法和移植性H22实体荷瘤小鼠为模型,检测不同剂量棉团铁线莲总皂苷的体内外杭肿瘤作用.结果:当质量浓度为0.1-lmg·mL-1时,其对体外培养的3株人肿瘤细胞HepG2、SMMC-7721和Hela的增值表现出显著的抑制作用,IC50依次为0.5298mg·mL-1、0.2047mg·mL-1、0.2877mg·mL-1.体内实验表明,棉团铁线莲总皂苷高(1.5g·kg-1)、中(0.75g·kg-1)、低(0.375g·kg-1) 3剂量组也较好的抑制了荷瘤小鼠瘤块

  12. 喜盐鸢尾根中化学成分的分离与结构鉴定%Isolation and structral identification of chemical constituents from Iris.halophila Pall.root

    Institute of Scientific and Technical Information of China (English)

    李小飞; 李冠; 杨博

    2013-01-01

    Four known isoflavones 5-hydroxy-6,7,4'-trimethoxy-isoflavone( Ⅰ ) ;5,7,3'-trihydroxy-6,4',5'-trime thoxy-isoflavone ( Ⅱ ) ;5,4'-dihydroxy-6,7-methylenedioxy-isoflavone ( Ⅲ) ;5-methoxy-4'-hydroxy-6,7-methylen edioxy-isoflavone(Ⅳ)were isolated from ethylacetate extract of the ethanol extract from Iris, halophila Pall. root, the structures of the four compounds were elucidated on the basis of UV,IR,MS and NMR data and correlative documents. All compounds were first isolated from Iris, halophila Pall.%从喜盐鸢尾(Iris.halophila Pall.)根乙醇提取物的乙酸乙醇提取部位中分离得到4个异黄酮类化合物,用UV、IR、MS和NMR等技术,结合文献,确定其结构为5-羟基-6,7,4′-三甲氧基异黄酮(Ⅰ);5,7,3′-三羟基-6,4′,5′-三甲氧基异黄酮(Ⅱ);5,4′-二羟基-6,7-亚甲二氧基异黄酮(Ⅲ);5-甲氧基-4′-羟基-6,7-亚甲二氧基异黄酮(Ⅳ).这四种化合物均首次从喜盐鸢尾(Iris.halophila Pall.)中分离得到.

  13. Analysis of BDS/GPS Integrated Navigation System in Asia-Pacific Region%BDS和GPS导航系统亚太地区定位性能分析

    Institute of Scientific and Technical Information of China (English)

    雷俊科

    2015-01-01

    通过仿真在轨的北斗卫星和GPS卫星,利用STK覆盖功能分析北斗、GPS和北斗/GPS组合导航系统在亚太地区的定位性能,并比较北斗/GPS组合卫星导航系统与单系统相比的优势。仿真结果表明北斗/GPS组合卫星导航系统在亚太地区有更好的可用性,能提供更高精度的导航定位服务。%The working BDS and GPS satellites are simulated in this paper. The performance of BDS,GPS and BDS/GPS integrated navigation system is analyzed by using STK coverage tools. The result shows that BDS/GPS integrated navigation system has a better availability and it can provide more precise poisoning service.

  14. Population genetic structure and mating system in the hybrid zone between Pinus sibirica Du Tour and P. pumila (Pall. Regel at the Eastern Baikal Lake shore

    Directory of Open Access Journals (Sweden)

    E.A. Petrova

    2013-12-01

    Full Text Available Genetic structure of sympatric Pinus sibirica Du Tour and P. pumila (Pall. Regel populations and putative interspecific hybrids between them was analyzed in the Baikal Lake region (Barguzin Biosphere Natural Reserve, Davsha River basin by means of 31 allozyme loci controlling 18 enzyme systems. Several alleles at loci Adh-1, Fest-2, Lap-3, Pgi-1, Sod-3 and Skdh-1 were diagnostic for P. sibirica, while alleles typical for P. pumila were detected at loci Gdh, Got-3, Lap-3, Mdh-2, Mdh-4, Pepca, Pgi-1, Pgd-2, Pgd-3, Pgm-1 and Pgm-2. All hybrids were heterozygous for the diagnostic Skdh-2 locus. Classification into hybrids and parental species using PCA analysis of multilocus allozyme genotypes had good correspondence with diagnoses made by morphological and anatomical analyses. Approximately 27% of embryos in P. pumila seeds had P. sibirica paternal contribution, and 8% of haplotypes in effective pollen pool combined alleles typical for P. pumila and P. sibirica, and therefore were classified as pollinated by the hybrids. About 83% of embryos in seeds from the hybrids most likely originated from fertilization by P. sibirica pollen, 14% from P. pumila and 3% from hybrid trees. This result favours the view that hybrids make both male and female contributions to the reproductive output of the population and confirm the presence of backcrosses and F2 hybrids.

  15. Paeonia lactiflora Pall. protects against ANIT-induced cholestasis by activating Nrf2 via PI3K/Akt signaling pathway

    Directory of Open Access Journals (Sweden)

    Ma X

    2015-09-01

    Full Text Available Xiao Ma,1,2 Yan-ling Zhao,2 Yun Zhu,3 Zhe Chen,1,2 Jia-bo Wang,4 Rui-yu Li,1,4 Chang Chen,1,2 Shi-zhang Wei,1,2 Jian-yu Li,3 Bing Liu,5 Rui-lin Wang,3 Yong-gang Li,3 Li-fu Wang,3 Xiao-he Xiao4 1Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China; 2Department of Pharmacy, 302 Military Hospital of People’s Liberation Army, Beijing, People’s Republic of China; 3Department of Integrative Medical Center, 302 Military Hospital of People’s Liberation Army, Beijing, People’s Republic of China; 4China Military Institute of Chinese Medicine, 302 Military Hospital of People’s Liberation Army, Beijing, People’s Republic of China; 5School of Chinese Medicine, The University of Hong Kong, Hong Kong Background: Paeonia lactiflora Pall. (PLP, a traditional Chinese herbal medicine, has been used for hepatic disease treatment over thousands of years. In our previous study, PLP was shown to demonstrate therapeutic effect on hepatitis with severe cholestasis. The aim of this study was to evaluate the antioxidative effect of PLP on alpha-naphthylisothiocyanate (ANIT-induced cholestasis by activating NF-E2-related factor 2 (Nrf2 via phosphatidylinositol 3-kinase (PI3K/Akt signaling pathway. Materials and methods: Liquid chromatography-mass spectrometry (LC-MS was performed to identify the main compounds present in PLP. The mechanism of action of PLP and its therapeutic effect on cholestasis, induced by ANIT, were further investigated. Serum indices such as total bilirubin (TBIL, direct bilirubin (DBIL, aspartate aminotransferase (AST, alanine aminotransferase (ALT, alkaline phosphatase (ALP, γ-glutamyl transpeptidase (γ-GT, and total bile acid (TBA were measured, and histopathology of liver was also performed to determine the efficacy of treatment with PLP. Moreover, in order to illustrate the underlying signaling pathway, liver glutathione (GSH content and mRNA or protein levels of glutamate

  16. Digital Gene Expression Analysis to Screen Disease Resistance-Relevant Genes from Leaves of Herbaceous Peony (Paeonia lactiflora Pall. Infected by Botrytis cinerea.

    Directory of Open Access Journals (Sweden)

    Saijie Gong

    Full Text Available Herbaceous peony (Paeonia lactiflora Pall. is a well-known traditional flower in China and is widely used for landscaping and garden greening due to its high ornamental value. However, disease spots usually appear after the flowering of the plant and may result in the withering of the plant in severe cases. This study examined the disease incidence in an herbaceous peony field in the Yangzhou region, Jiangsu Province. Based on morphological characteristics and molecular data, the disease in this area was identified as a gray mold caused by Botrytis cinerea. Based on previously obtained transcriptome data, eight libraries generated from two herbaceous peony cultivars 'Zifengyu' and 'Dafugui' with different susceptibilities to the disease were then analyzed using digital gene expression profiling (DGE. Thousands of differentially expressed genes (DEGs were screened by comparing the eight samples, and these genes were annotated using the Gene ontology (GO and Kyoto encyclopedia of genes and genomes (KEGG database. The pathways related to plant-pathogen interaction, secondary metabolism synthesis and antioxidant system were concentrated, and 51, 76, and 13 disease resistance-relevant candidate genes were identified, respectively. The expression patterns of these candidate genes differed between the two cultivars: their expression of the disease-resistant cultivar 'Zifengyu' sharply increased during the early stages of infection, while it was relatively subdued in the disease-sensitive cultivar 'Dafugui'. A selection of ten candidate genes was evaluated by quantitative real-time PCR (qRT-PCR to validate the DGE data. These results revealed the transcriptional changes that took place during the interaction of herbaceous peony with B. cinerea, providing insight into the molecular mechanisms of host resistance to gray mold.

  17. Shanghai Acrobats pall on Chinese?

    Institute of Scientific and Technical Information of China (English)

    BirteZimmer

    2003-01-01

    You can feel the vibration in the air, wheneverybody is watching with tension how thesmall Chinese woman starts to climb up a swinqinq board on a desk while she is balancing a pyramid of four tablets with filled glasses ana candlesticks on her forehead. She manages this task with ease

  18. Numerical Analysis of Perturbation Forces of GPS and BDS Satellites%GPS/BDS卫星摄动力数值分析

    Institute of Scientific and Technical Information of China (English)

    宋传峰; 朱李忠; 赵忠海; 张洪文

    2016-01-01

    由精密星历利用拉格朗日插值公式求二次导数的方法计算了卫星在J2000.0惯性坐标系下的总加速度;利用现有的力模型计算了地球中心引力,地球非球形摄动力,太阳、月球和其他行星的摄动力,地球固体潮摄动力,相对论效应摄动力对GPS/BDS卫星所产生的加速度数值大小;利用G-file里的BERNE太阳光压模型参数计算了GPS卫星太阳光压摄动加速度大小;对GPS/BDS卫星所受的不同摄动力进行了数值分析,对同一摄动力对不同类型卫星的影响进行了数值分析比较。结果表明,现有力模型与GPS/BDS卫星所受的实际作用力仍有一定的差距,不同类型卫星所受摄动力有明显差异,在精密定轨的实际应用中应根据不同类型卫星建立合适的力学模型。%This paper calculated the total acceleration of the satellite in J2000.0 inertial coordinate system using the second derivative of Lagrange's interpolation formula by the precise ephemeris.Based on mechanical models, this paper computed the acceleration of GPS and BDS satellites due to the gravity of Earth's center and the perturbation forces of the Earth's non-spherical, the sun, the moon, other planets, Earth solid tide and the relativity.Using the BERNE solar pressure module parameters in G-file, this paper al-so computed the solar radiation pressure perturbation acceleration of GPS satellite.After that, we made numerical analysis and com-parison of different perturbation forces and different types of satellites.It's concluded that the difference between mechanical models and true forces of satellite is evident.It's also concluded that different types of satellite suffered significant difference in perturbation forces especially for BDS GEO satellite due to the influence of maneuver force.Therefore, in the practical application of precise orbit determination, establish a suitable mechanical model is needed.

  19. A drift line bias estimator: ARMA-based filter or calibration method, and its application in BDS/GPS-based attitude determination

    Science.gov (United States)

    Liang, Zhang; Yanqing, Hou; Jie, Wu

    2016-06-01

    The multi-antenna synchronized receiver (using a common clock) is widely applied in GNSS-based attitude determination (AD) or terrain deformations monitoring, and many other applications, since the high-accuracy single-differenced carrier phase can be used to improve the positioning or AD accuracy. Thus, the line bias (LB) parameter (fractional bias isolating) should be calibrated in the single-differenced phase equations. In the past decades, all researchers estimated the LB as a constant parameter in advance and compensated it in real time. However, the constant LB assumption is inappropriate in practical applications because of the physical length and permittivity changes of the cables, caused by the environmental temperature variation and the instability of receiver-self inner circuit transmitting delay. Considering the LB drift (or colored LB) in practical circumstances, this paper initiates a real-time estimator using auto regressive moving average-based (ARMA) prediction/whitening filter model or Moving average-based (MA) constant calibration model. In the ARMA-based filter model, four cases namely AR(1), ARMA(1, 1), AR(2) and ARMA(2, 1) are applied for the LB prediction. The real-time relative positioning model using the ARMA-based predicting LB is derived and it is theoretically proved that the positioning accuracy is better than the traditional double difference carrier phase (DDCP) model. The drifting LB is defined with a phase temperature changing rate integral function, which is a random walk process if the phase temperature changing rate is white noise, and is validated by the analysis of the AR model coefficient. The auto covariance function shows that the LB is indeed varying in time and estimating it as a constant is not safe, which is also demonstrated by the analysis on LB variation of each visible satellite during a zero and short baseline BDS/GPS experiment. Compared to the DDCP approach, in the zero-baseline experiment, the LB constant

  20. Analysis of BDS Applications to Carry out Conformity Assessment%北斗卫星导航系统应用产品开展合格评定工作的思考

    Institute of Scientific and Technical Information of China (English)

    许冬彦; 马丽娜; 王维嘉

    2015-01-01

    As well as BeiDou navigation satellite system (BDS)begin to provide Full operational Service for China and its surrounding areas formally by the end of 2012,the government also gave out policies about BDS applications,and the industry and regional application demonstration propel steadily,BDS ushers a major historical opportunity of “large-scale,community, industrialization and internationalization”.Application products based on the BDS start to put into the mass market,there are so many types of manufacturers and products but lack of brand trust,so the consumers have difficult to choose from these products,these will impede the development of BDS products in domestic and international markets.Carry out conformity as-sessment of BDS applications products will help to improve the law-abiding awareness of market players,build market order of fair competition,ensure the quality and safety of various goods and service in the market,protect consumer,guide the orderly development of the market,and promote international trade and BDS industry developed health and sustainable.In this paper, we researched the significance of BDS conformity assessment,studied needs analysis as well as domestic and overseas status of BDS conformity assessment,put forward some proposal about working mechanism to carry out conformity assessment of BDS, hoping to play a role as reference to carry out conformity assessment work of products of satellite applications.%随着北斗卫星导航系统2012年底正式提供运行服务,国家对北斗系统应用政策出台,北斗系统导航行业和区域示范应用稳步推进,北斗系统导航迎来“规模化、社会化、产业化、国际化”的重大历史机遇。合格评定作为证明执行法律和贯彻标准的一个有力手段,世界发达国家非常重视推行合格评定工作,普遍实行了产品认证及市场准入制度。开展北斗系统应用产品的合格评定有利于提高市场主体的守法意

  1. BDS thin film damage competition

    Energy Technology Data Exchange (ETDEWEB)

    Stolz, C J; Thomas, M D; Griffin, A J

    2008-10-24

    A laser damage competition was held at the 2008 Boulder Damage Symposium in order to determine the current status of thin film laser resistance within the private, academic, and government sectors. This damage competition allows a direct comparison of the current state-of-the-art of high laser resistance coatings since they are all tested using the same damage test setup and the same protocol. A normal incidence high reflector multilayer coating was selected at a wavelength of 1064 nm. The substrates were provided by the submitters. A double blind test assured sample and submitter anonymity so only a summary of the results are presented here. In addition to the laser resistance results, details of deposition processes, coating materials, and layer count will also be shared.

  2. 白血球除去フィルター(Sepacell R-500 A/Pall PL 50/100)使用による抗血小板抗体産生に及ぼす効果

    OpenAIRE

    下山, 丈人; 藤村, 吉博; 河本, 順雄; 西田, 幸世; 吉田, 英里; 水本, 保子; 八木, 秀男; 松本, 雅則; 山中, 貴世; 森井, 武志; 西川, 潔; 成田, 亘啓

    1992-01-01

    To minimize various post-transfusion complications caused by white blood cell components, Sepacell R-500 A filters (Asahi Medical) for red blood cell products and PL 50/100 filters (Pall) for platelet products to remove white blood cells were clinicallyused in a total of 46 patients with leukemia and its allied disorders, and the results were compared with those of 19 patients with whom the filters were not used. Platelet allo-antibodies, assayed by mixed passive haemagglutination (MPHA) meth...

  3. Water absorbance features of mucilage on the seeds of a desert ephemeral plant, Plantago minuta Pall., and its role in germination of the seeds under drought stress%小车前(Plantago minuta Pall.)种子表面粘液物质的吸水特性及其对种子在干旱环境中萌发的影响

    Institute of Scientific and Technical Information of China (English)

    伍晨曦; 孙羽; 冯固

    2009-01-01

    为了理解荒漠短命植物小车前(Plantago minuta Pall.)种子表面的粘液物质对种子在干旱环境中萌发的作用,在室内控制条件下研究了粘液物质的吸水保水特性、剥离粘液物质的种子(无粘液种子)和保留粘液物质的种子(粘液种子)在-1.15~-0.15 MPa不同渗透胁迫条件下的萌发状况.结果表明: (1)小车前种子表面的粘液物质干重占粘液种子干重的5.6%;在去离子水中,粘液物质可以吸收相当于其自身干重217.1倍的水分;粘液物质的存在使得小车前种子的吸水倍数由2倍增加至14倍,从而保证为种子萌发提供充足的水分;(2)干燥的粘液种子吸水2h后即达到饱和,而吸水饱和后的粘液种子在室温下晾置,经过48h后又干燥失水恢复至原重;(3)在去离子水中或低渗透胁迫(-0.33~-0.15 MPa) 条件下,粘液物质吸水作用能促进小车前种子萌发,粘液种子3d的发芽势和10d的总萌发率均显著高于无粘液种子;在高渗透胁迫(-1.15~-0.73MPa)条件下,粘液种子3d的发芽势显著低于无粘液种子的,而10d的总萌发率与无粘液种子的没有显著差别,表明粘液物质在干旱条件下可能从种子而非外界环境中吸取水分,减缓了种子萌发速率.通过上述结果可以认为小车前种子表面的粘液物质在早春干湿交替剧烈的荒漠生境中起到通过调节水分来调节种子萌发的作用,这种萌发策略大大降低了因大批种子同时萌发导致幼苗受旱甚至种群灭亡的潜在风险.

  4. Design of GPS/BDS-based positioning and tracking system for moving targets%基于GPS/BDS的移动目标定位追踪系统设计

    Institute of Scientific and Technical Information of China (English)

    张超; 顾济华

    2015-01-01

    利用GPS(全球卫星定位系统)和BDS(北斗卫星导航系统)联合定位技术,设计了一款针对移动目标的高精度定位与跟踪系统.系统主要包括移动目标通信终端、GSM网络、GIS电子地图等.其中,核心部分——移动目标通信终端硬件由ATGM331C单元、TC35I单元和STC12C5A60S2微处理器单元等构成;其软件设计主要包括:微处理器初始化、GPS/BDS解码、短信命令解码和AT命令控制等.实践测试结果表明:该系统运行稳定,且移动目标通信终端具有定位精度高、体积小、功耗低、操作简单方便等特点,应用前景广阔.%By using the combined positioning technology of global positioning system(GPS)and BeiDou navigation satellite system(BDS),a high accuracy positioning and tracking system for moving targets was designed. The system consists of commu-nication terminal of moving target,GSM network and electronic map of GIS mainly. As the key part of the whole system,the hardware of the moving target communication terminal is composed of ATGM331C module,TC35I module and STC12C5A60S2 microprocessor. The software design includes microprocessor initialization,decoding of GPS/BDS navigation information,decoding of short message service commands and the AT command control mainly. The practical testing results indicate that the system can work steadily,and the moving target communication terminal has the characteristics of high accuracy positioning,small size,low power consumption and convenient operation. The system has a broad application prospect.

  5. 白刺果实提取物的体外抑菌活性研究%In vitro antimicrobial activity of extracts from fruits of Nitraria sibirica pall.

    Institute of Scientific and Technical Information of China (English)

    张桂霞; 齐敬浩; 任旭; 陈贵林

    2012-01-01

    Evaluated the in vitro antimicrobial activity of Nitraria sibirica Pall. Fruits extracts to provide the basis for utilizating Nitraria resources and developing natural food antiseptic. Nitraria sibirica Pall. fruits were extracted with 95% ethanol,then fractionated with petroleum ether,chloroform,ethyl acetate and n-butanol respectively. The filter paper disc diffusion method was performed to determine the influence of the different extracts on the growths of 3 bacterium(Escherichia coil, Bacillus subtilis, Staphyloccocus aureus) and 4 fungus(Penici//ium sp., Rhizopus sp. ,Aspergillus niger, Saccharomyces cerevisiae ) ,and the minimal inhibitory concentrations(MICs) of ethyl acetate extracts againts the 3 kinds of bacterium were tested using the doubling dilution method.The results showed that the ethyl acetate,ethanol and chloroform extracts had antibacterial activity against the 3 kinds of bacterium. In addition ,the ethyl acetate extracts presented higher antibacterial activity than others. The MIC of ethyl acetate extract against Escherichia coil, Bacillus subtilis, Staphyloccocus aureus were 25,25, 50mg/mL. None of the extracts exhibited inhibitory activity against Fungus.%探讨白刺果实提取物的体外抑菌活性,以期为白刺果实的综合利用及天然食品防腐剂的开发提供依据。用石油醚、氯仿、乙酸乙酯和正丁醇分别对白刺果实95%乙醇提取物进行萃取,纸片法测定各萃取部分对大肠杆菌、枯草芽孢杆菌、金黄色葡萄球菌、酵母菌、青霉、根霉和黑曲霉7种常见的食源性污染菌的抑菌效果,并通过倍比稀释法测定乙酸乙酯部分对其中3种细菌的最低抑菌浓度。结果表明:白刺果实乙酸乙酯部分、乙醇部分和氯仿部分对3种供试细菌均有抑菌作用,其中乙酸乙酯部分抑菌效果最好,且乙酸乙酯部分对3种细菌的抑制强弱顺序为:枯草芽孢杆菌〉大肠杆菌〉金黄色葡萄球菌

  6. Seedling emergence and salt tolerance of Suaeda physophora Pall. under salt stress%盐胁迫下囊果碱蓬出苗状况及苗期抗盐性

    Institute of Scientific and Technical Information of China (English)

    高奔; 宋杰; 刘金萍; 史功伟; 范海; 赵可夫; 王宝山

    2009-01-01

    We investigated the effect of salinity on seedling emergence, seedling growth, ion accumulation and the rate of photosynthetic oxygen evolution of Suaeda physophora Pall. The optimum salt concentration for growth of S. physophora was about 200 mmol/L NaCl. High concentrations of NaCl (400 and 600 mmol/L) did not decrease seedling emergence, while 200 mmol/L NaCl increased it. The rate of leaf photosynthetic oxygen evolution was decreased at 400 and 600 mmol/L NaCl. Maintaining a relatively high K~+/Na~+ ratio and water content in leaves under high concentrations of NaCl may be an important mechanism for the adaptation of S. physophora to high salinity.%研究了盐胁迫对囊果碱蓬出苗、幼苗生长、离子积累以及光合放氧速率的影响.囊果碱蓬生长的最适盐浓度在200 mmol/L NaCl左右.高浓度NaCl(400 mmol/L和600 mmol/L)没有显著降低其出苗率,200 mmol/L NaCl对出苗率具有促进作用.400 mmol/L和600 mmol/L NaCl显著降低了光合放氧速率.囊果碱蓬在高浓度NaCl处理下能够维持叶片较高的K~+/Na~+ 及含水量可能是其适应高盐生境的重要机制.

  7. 理化因子对芍药花色苷呈色的影响∗%Effect of Physical and Chemical Factors on Coloring of Anthocyanins Obtained from Herbaceous Peony (Paeonia lactiflora Pall.)

    Institute of Scientific and Technical Information of China (English)

    赵大球; 郝召君; 陶俊

    2015-01-01

    研究了理化因子对芍药花色苷溶液在体外呈色的影响。结果表明:芍药花色苷溶液在黑暗、室温(20℃)等条件下表现稳定;在自然光、紫外光、蓝光、白光、低温(4℃)、氧化剂(H2O2)、还原剂(Na2SO3)、Cu2+、Mn2+、Mg2+、Zn2+、Fe2+等条件下易于降解,颜色变淡;而红光、黄光、高温(40℃、60℃)、Na+对花色苷溶液具有一定的增色作用;不同pH对芍药花色苷溶液呈色影响并不一致。研究结果可为通过理化因子来调控芍药花色奠定基础。%The effect of physical and chemical factors on the coloring of anthocyanins in herbaceous peony (Paeonia lactiflora Pall.) was investigated in this paper. The results showed that darkness and room temperature (20℃) had no effect on the stability of anthocyanins. Furthermore, natural light, ultraviolet light, blue light, white light, low temperature (4℃), oxidant (H2O2), reductant (Na2 SO3 ) , Cu2+, Mn2+, Mg2+, Zn2+and Fe2+promoted the degradation of anthocyanins. In addition, red light, yellow light, high temperature (40℃ and 60℃) and Na+had color enhancing effect on an⁃thocyanins, and different pH value had different color effect on anthocyanins. These results would lay a foundation for regulating P. lactiflora flower color by physical and chemical factors.

  8. Haridusvabadus / ajakirjast "The Freeman" tlk. Riinu Pall

    Index Scriptorium Estoniae

    2000-01-01

    Praegune haridussüsteem on vastuolus individuaalse vabaduse ja vastutuse põhimõtetega vabas ühiskonnas, hariduse kvaliteedi tõstmise asemel on süsteemis madal tase ja ebatõhus vahendite kasutamine

  9. Palle Qvist's Blog about Digital Teaching

    DEFF Research Database (Denmark)

    Qvist, Palle

    2010-01-01

    Blog created to support the first pedagogical day about e-learning arranged by the official AAU – “Pedagogical open day in Aalborg 17th of March 2010″. New articles added continuosly......Blog created to support the first pedagogical day about e-learning arranged by the official AAU – “Pedagogical open day in Aalborg 17th of March 2010″. New articles added continuosly...

  10. Comparative Study Between Effects of Smilax sieboldii Miq., Clematis chinensis Osbeck.and C.hexapetala Pall.on Non-specific Immunity%粘鱼须威灵仙棉团铁线莲对非特异性免疫的影响比较

    Institute of Scientific and Technical Information of China (English)

    石强

    2011-01-01

    Objective To compare the effects of Smilax sieboldii Miq. , Clematis chinensis Osbeck. and C. hexapetala Pall, on non-specific immunity, and further determine the feasibility of Smilax sieboldii Miq. to be used as drug.Methods The carbon granules clearance test in mice and chicken red blood cell phagocytosis test were carried out to compare the effects. Results All of Smilax sieboldii Miq. , Clematis chinensis Osbeck. and C.hexapetala Pall,inhibited the phagocytic function of monocyte-macrophage and abdominal cavity macrophage in mice, and reduced non-specific immune function.Conclusion Smilax sieboldii Miq. can be used equivalently as Clematis chinensis Osbeck. for the treatment of rheumatism.%目的 比较粘鱼须、威灵仙、棉团铁线莲对非特异性免疫的影响,为粘鱼须能否作为威灵仙入药提供科学依据.方法 选择小鼠碳粒廓清法和腹腔巨噬细胞吞噬鸡红细胞法进行比较3种药物.结果 粘鱼须、威灵仙、棉团铁线莲均能抑制小鼠单核巨噬细胞和腹腔巨噬细胞的吞噬作用,降低机体非特异性免疫反应能力.结论 粘鱼须可以作为祛风湿药威灵仙使用.

  11. 粘鱼须威灵仙和棉团铁线莲对细胞免疫与体液免疫的影响比较%Comparing Study of the Effects of Smilax sieboldii Miq., Clematis chinensis Osbeck. and C. hexapetela Pall on Cellular Immunity and Humoral Immunity

    Institute of Scientific and Technical Information of China (English)

    石强

    2011-01-01

    Objective To compare the effects of Smilax sieboldii Miq. , Clematis chinensis Osbeck. and C. hexapetela Pall on cellular and humoral immunity, and further determine the feasibility of Smilax sieboldii Miq. to be used as a drug. Methods Three cellular immune indexes including the formation rate of erythrocyte rosette, amount of T cell subsets and effects on delayed type hypersensitivity; two humoral immnue ones including the number of plaque forming cell ( PFC) and amount of serum hemolysin were compared. Results All of Smilax sieboldii Miq. , Clematis chinensis Osbeck. and C. hexapetela Pall decoction were able to inhibit the activity of T-lymphocyte and reduce the humoral immune function. Conclusion Smilax sieboldii Miq. can be used equivalently as Clematis chinensis Osbeck. for the treatment of rheumatism.%目的 比较粘鱼须、威灵仙、棉团铁线莲对细胞免疫和体液免疫的影响,为粘鱼须作为威灵仙入药提供科学依据.方法 选择影响玫瑰花环形成、T细胞亚群数量、迟发型变态反应等3个细胞免疫的指标和影响抗体形成细胞数量、血清溶血素数量等2个体液免疫的指标进行比较.结果 粘鱼须、威灵仙、棉团铁线莲均能抑制T细胞功能,降低机体细胞免疫反应能力.结论 粘鱼须可以作为祛风湿药威灵仙使用.

  12. 一种适用于 BDS/GPS 组合姿态测量的选星算法%A Satellite Selection Algorithm in BDS/GPS Combination Attitude Determination

    Institute of Scientific and Technical Information of China (English)

    王兵浩; 吕志伟; 吕金浩

    2015-01-01

    With the development of the Global Navigation Satellite System (GNSS ) , multi‐system application has became a hot spot of research .What comes with the mature of GNSS is the multiplied number of visible satellites w hich results in a more perfect structure of satellites and higher precision ,also the expanded design matrix and amount of calculation . The attitude determination based on GNSS has the advantages of low cost ,no error accumu‐lation ,weather free ,etc .Limited by the real‐time demand of attitude measuring ,a fast , reasonable algorithm of satellites selection in the GNSS attitude measurement is of great sig‐nificance .In this paper ,the author proposes an algorithm applicable to BDS/GPS combina‐tion attitude determination .This algorithm greatly reduces the amount of calculation in the process of one epoch on the premise of no too much loss of attitude measurement precision , w hich has a certain significance in the practical application .%随着GNSS系统的不断发展和完善,多卫星导航系统组合应用成为研究的热点。多系统的逐渐成熟带来的是单一历元可见卫星数量的成倍增加。卫星结构更加完善,解算精度更高,但计算量猛增。利用GNSS系统进行姿态测量具有组成简单、成本低、不受天气影响、没有误差积累等优点。受限于姿态测量的实时性要求,对观测到的卫星进行快速、合理的选择,在尽可能保证精度的前提下,满足实时性要求,对GNSS姿态测量具有重大的意义。提出了一种适用于BDS/G PS双系统组合姿态测量的选星算法,在保证姿态角测量精度较少损失的前提下,大大降低了单历元的计算量,在实际工程应用中具有一定的意义。

  13. BDS/GPS/GLONASS/GALILEO 组合卫星导航系统仿真分析%Simulation and Analysis of BDS/GPS/GLONASS/GALILEO Integrated Satellite Navigation System

    Institute of Scientific and Technical Information of China (English)

    潜成胜; 马大喜

    2013-01-01

    全球卫星定位系统因其高精度、全天候等优点而被广泛应用,但是单一导航系统容易受环境及人为干扰,导致在区域精度和连续性上有较大问题。本文对组合导航系统进行仿真,组合中国BDS、美国GPS、俄罗斯GLONASS和欧盟的GALILEO四个全球卫星导航系统,利用仿真数据对目前GPS单一系统、当前不完整组合系统、未来完整组合系统在赣州地区的几何精度衰减因子( GDOP)值、可见卫星数及导航精度进行对比分析。通过仿真结果可以发现,与单一的GPS系统相比,组合系统在可见卫星数、GDOP和导航精度上都有非常大的优势。%The Global satellite Positioning System is applied widely because of its advantages of high accuracy and all-weather operation .However ,a single satellite positioning system is more susceptible to environmental and human dis-turbance ,which causes significant problems about precision and continuity in region .In this paper ,an integrated naviga-tion system which includes the Chinese BDS ,the U.S.GPS,the Russian GLONASS and the EU’s GALILEO was applied to be simulated .And the simulated data was used to compare the current single GPS system ,the current incomplete inte-grated system and the future complete integrated system ’ s GDOP,the number of visible satellites and navigation accuracy in Ganzhou area .The simulation results reveal that the integrated navigation system is more advantage than the single GPS system in GDOP ,the number of visible satellites and navigation accuracy .

  14. Bd/s -> mu+ mu- in ATLAS

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00215268; The ATLAS collaboration

    2016-01-01

    The ATLAS Experiment has conducted a search for the rare decays of Bs and Bd into mu+mu-. 25 fb−1 of integrated luminosity of proton-proton collisions collected during LHC Run 1 were studied and new results were obtained, as presented in this talk. An upper limit is set on the Bd to mu+mu- branching ratio of BR(Bd to mu+mu-) < 4.2×10−10 at 95% confidence level. For Bs, ATLAS measurement yields the branching ratio BR(Bs to mu+mu-)=(0.9+1.1−0.8)×10−9. The result is consistent with the Standard Model expectation and other available measurements.

  15. Bd/s -> mu+ mu- in ATLAS

    CERN Document Server

    Guenther, Jaroslav; The ATLAS collaboration

    2016-01-01

    The ATLAS Experiment has conducted a search for the rare decays of Bs and Bd into mu+mu-. 25 fb−1 of integrated luminosity of proton-proton collisions collected during LHC Run 1 were studied to provide new results presented in this talk. An upper limit is set on the branching ratio BR(Bd to mu+mu-) < 4.2×10−10 at 95% confidence level. For Bs, ATLAS measurement yields the branching ratio BR(Bs to mu+mu-)=(0.9+1.1−0.8)×10−9. The result is consistent with the Standard Model expectation and other available measurements.

  16. 新疆盐生植物猪毛菜逆向运输蛋白基因SaNHX1 3'-RACE的克隆及序列分析%Clone and Sequence Analysis of 3'RACE of Antiporter Protein Gene SaNHX1 in Xinjiang Halophytes Plant Salsola collina Pall.

    Institute of Scientific and Technical Information of China (English)

    张雨良; 罗淑萍; 杨峰山; 魏岩; 袁辉; 郭长奎

    2008-01-01

    以新疆盐生植物猪毛菜( Salsola collina Pall.)为材料提取总RNA,根据 NHX1家族同源序列保守区设计1对简并引物,进行RT-PCR扩增,得到猪毛菜逆向运输蛋白基因cDNA中间一段619 bp序列.再用快速扩增cDNA 3'末端(3' RACE)方法,得到约1 000 bp 3'末端序列.将两段序列进行拼接,得到猪毛菜长为1 585 bp(GenBank登陆号为EU072932)的逆向运输蛋白基因(SaNHX1) cDNA序列,编码370个氨基酸,其编码序列、氨基酸序列与同科耐盐植物盐角草相应序列同源性为85%和87%,研究为进一步克隆猪毛菜NHX1全基因序列和研究其功能打下基础.

  17. Accountability and transparency of financial sector supervision / Pall Gunnar Palsson

    Index Scriptorium Estoniae

    Palsson, Pall Gunnar

    2001-01-01

    Finantsjärelvalve üheks oluliseks tingimuseks on läbipaistvus. Rahvusvahelise Valuutafondi poolt vastu võetud raha- ja rahanduspoliitika heade tavade koodeksist. Ülevaade Islandi finantsinspektsiooni töökorraldusest

  18. Shoot multiplication and plant regeneration in Caragana fruticosa (Pall.) Besser

    Institute of Scientific and Technical Information of China (English)

    ZHAI Xiao-jie; YANG Ling; SHEN Hai-long

    2011-01-01

    Different nutrient media can affectin vitro culturing protocols,and experimentation under varied growth conditions is valuable in plants where in vitro methods are in preliminary stages.We carried out the first in vitro propagation studies for the endangered species Caragana fruticosa (Fabaceae).We evaluated various nutrient media for their inpact on shoot elongation and axillary bud proliferation using different concentrations of 6-benzylaminopurine (BA) and α-naphthaleneacetic acid (NAA).Shoot elongation was evaluated based on adventitious shoot primary culture and subculture regeneration from Caragana seedlings.Our goal was to improve both micropropagation and regeneration in C.fruticosa.MS nutrient media was superior to 1/2MS macronutrients,DKW,QL,and WPM for shoot elongation and axillary shoot proliferation.Shoots grown on 1/2MS and WPM exhibited some chlorosis,and shoots on QL produced larger leavers than plants growing on normal medium.The shoot proliferation coefficient on MS media supplemented with 2.22 μM BA and 0.44 μM BA + 2.69 μM NAA was significantly higher than that with other treatments in the primary culture.Shoots on 2.22 μM BA showed a higher proliferation coefficient (3.17) than others in the subculture.Shoots were rooted on 1/2MS medium with the addition of different concentrations of NAA.The optimal concentration for rooting was 0.27 μM NAA (74%).Roots exhibited many stout and long root hairs.Survivl of established plantlets was 82% at 30 days after transfer to soil.Plants established in the green house showed normal growth and displayed no apparent morphological differences compared to stock plants.

  19. Pall oma väravasse? / Heidi Pruuli

    Index Scriptorium Estoniae

    Pruuli, Heidi, 1954-

    2008-01-01

    ETV peatoimetaja arvates näitavad nii Riigikogu kui ka valitsus rahvusringhäälingu vastu üles ükskõiksust ja tõrjuvust ning ta viitab litsentsimaksu kaotamisele, samal ajal kui rahvusringhäälingu tänavusi eelarvetoetusi vähendati 37 mln. krooni võrra

  20. Sotsiaaluuringud aitavad juhtida perepoliitikat / Kati Karelson, Katre Pall

    Index Scriptorium Estoniae

    Karelson, Kati

    2003-01-01

    Riiklikust perepoliitikast, selle tulemuste analüüs ja võrdlus teistes Euroopa riikides rakendatud institutsionaalsete meetmetega. Artikkel põhineb Euroopa Komisjoni 5. raamprogrammi projektina rahastatud ja aastail 2000-2003 korraldatud uuringu IPROSEC tulemustel. Skeemid. Tabel

  1. 温度、PEG处理和盐胁迫对小车前种子萌发的影响%Effects of Temperature, Stress Induced by PEG-8000 and NaCl Solutions on Seed Germination of Plantago minuta(Pall)

    Institute of Scientific and Technical Information of China (English)

    田美华; 唐安军

    2011-01-01

    本研究旨在探讨短命植物小车前(Plantago minuta Pall.)种子的休眠特性及其对温度、干旱和盐胁迫等因子的响应特点.在10、15、20、25和30℃的不同恒温条件以及每日15、25℃各12h的变温条件下,新鲜的小车前种子萌发率较低,其最高萌发率为15%.在经60d的干藏后,种子休眠被解除;已解除休眠的种子的萌发是温度依赖的,以20℃为最佳,此时萌发率为97%.解除休眠后的小车前种子萌发率随PEG-8000和NaCl溶液浓度的升高而降低.结果表明,小车前种子具初级休眠,且在长期适应环境过程中形成了独特的生态适应性;对干旱和盐胁迫有一定的耐性.进一步推知,短命植物小车前特定的休眠特点和萌发模式是其适应与进化的重要基础;此种植物在严重干旱发生早期完成生活史,是避旱型植物.%The present study aimed at investigating dormant characteristics and responses to germination temperature, drought and salt stress of Plantago minuta seeds. Freshly harvested seeds of P. Minuta did not germinate well and showed innate dormancy at broad range of constant temperatures (10, 15, 20, 25 and 30 ℃ ) and an altering temperature of 25/15 ℃ with a 12 h photoperiod. However, the dormancy was broken after 60 d dry storage at 4 ℃. Obviously, the germination was temperature-dependent and the optimum temperature was 20 ℃ with the germination of 97% in light. Also, the decrease in the final germination percentages was observed with increase in concentration of both PEG-8000 and NaCl solutions. It suggested that P. Minuta produces innate dormant seeds and develops its unique ecological adaptation although this species is able to tolerate weak salt stress and water deficiency. Based on these results above, it could be inferred that the particular dormant characteristics and germination pattern underlie its adaptation to the desert environment and evolve in the field. Moreover, P. Minuta has an

  2. BDS Thin Film UV Antireflection Laser Damage Competition

    Energy Technology Data Exchange (ETDEWEB)

    Stolz, C J

    2010-10-26

    UV antireflection coatings are a challenging coating for high power laser applications as exemplified by the use of uncoated Brewster's windows in laser cavities. In order to understand the current laser resistance of UV AR coatings in the industrial and university sectors, a double blind laser damage competition was performed. The coatings have a maximum reflectance of 0.5% at 355 nm at normal incidence. Damage testing will be performed using the raster scan method with a 7.5 ns pulse length on a single testing facility to facilitate direct comparisons. In addition to the laser resistance results, details of deposition processes and coating materials will also be shared.

  3. Summary of the BDS and MDI CLIC08 Working Group

    CERN Document Server

    Tomás, R; Ahmed, I; Ambatu, PK; Angal-Kalinin, D; Barlow, R; Baud, J P; Bolzon, B; Braun, H; Burkhardt, H; Burt, GC; Corsini, R; Dalena, B; Dexter, AC; Dolgashev, V; Elsener, K; Fernandez Hernando, JL; Gaillard, G; Geffroy, N; Jackson, F; Jeremie, A; Jones, RM; McIntosh, P; Moffeit, K; Peltier, F; Resta-López, J; Rumolo, G; Schulte, D; Seryi, A; Toader, A; Zimmermann, F

    2008-01-01

    This note summarizes the presentations held within the Beam Delivery System and Machine Detector Interface working group of the CLIC08 workshop. The written contributions have been provided by the presenters on a voluntary basis.

  4. ИЗУЧЕНИЕ КОМПОНЕНТНОГО СОСТАВА ЭФИРНЫХ МАСЕЛ ЛИСТЬЕВ CRATAEGUS SANGUINEA PALL. И ТРАВЫ CONIUM MACULATUM L. ИЗ ФЛОРЫ БАШКОРТОСТАНА

    OpenAIRE

    Трофимова, С.; Булгаков, Т.; Хасанова, С.; Кудашкина, Н.

    2013-01-01

    Исследован компонентный состав полученных методом перегонки с водяным паром эфирных масел из листьев боярышника кроваво-красного Crataegus Sanguinea Pall и травы болиголова пятнистого Conium Maculatum L. методом хромато-масс-спектрометрии. В эфирном масле листьев боярышника выявлено 44 соединения, из них идентифицировано 18. В эфирном масле травы болиголова пятнистого выявлено 29 соединений, из них идентифицировано 11. Установлено, что в составе эфирных масел листьев боярышника и травы болиго...

  5. Evaluation of the Effects of Sativex (THC BDS: CBD BDS) on Inhibition of Spasticity in a Chronic Relapsing Experimental Allergic Autoimmune Encephalomyelitis: A Model of Multiple Sclerosis

    OpenAIRE

    Hilliard, A.; Stott, C.; Wright, S; Guy, G.; Pryce, G.; Al-Izki, S.; Bolton, C; Giovannoni, G.

    2012-01-01

    This study investigated the antispasticity potential of Sativex in mice. Chronic relapsing experimental allergic encephalomyelitis was induced in adult ABH mice resulting in hind limb spasticity development. Vehicle, Sativex, and baclofen (as a positive control) were injected intravenously and the “stiffness” of limbs assessed by the resistance force against hind limb flexion. Vehicle alone caused no significant change in spasticity. Baclofen (5 mg/kg) induced approximately a 40% peak reducti...

  6. Evaluation of the Effects of Sativex (THC BDS: CBD BDS) on Inhibition of Spasticity in a Chronic Relapsing Experimental Allergic Autoimmune Encephalomyelitis: A Model of Multiple Sclerosis.

    Science.gov (United States)

    Hilliard, A; Stott, C; Wright, S; Guy, G; Pryce, G; Al-Izki, S; Bolton, C; Giovannoni, G

    2012-01-01

    This study investigated the antispasticity potential of Sativex in mice. Chronic relapsing experimental allergic encephalomyelitis was induced in adult ABH mice resulting in hind limb spasticity development. Vehicle, Sativex, and baclofen (as a positive control) were injected intravenously and the "stiffness" of limbs assessed by the resistance force against hind limb flexion. Vehicle alone caused no significant change in spasticity. Baclofen (5 mg/kg) induced approximately a 40% peak reduction in spasticity. Sativex dose dependently reduced spasticity; 5 mg/kg THC + 5 mg/kg CBD induced approximately a 20% peak reduction; 10 mg/kg THC + 10 mg/kg CBD produced approximately a 40% peak reduction in spasticity. Sativex has the potential to reduce spasticity in an experimental mouse model of multiple sclerosis (MS). Baclofen reduced spasticity and served as a positive control. Sativex (10 mg/kg) was just as effective as baclofen, providing supportive evidence for Sativex use in the treatment of spasticity in MS. PMID:22928118

  7. Adaptation mechanisms of Coluria geoides (Pall.) Ledeb. to different ecological factors

    OpenAIRE

    Tatiana V. Leonova

    2013-01-01

    Ontogenesis of each individual occurs particularly. Polyvariation of individual development determines existence of species in various ecological-coenotic conditions, is important for adaptation and provides resistance of coenopopulations.

  8. Microbial Growth on Pall-rings : A problem when upgrading biogas with the technique water absorption

    OpenAIRE

    Tynell, Åsa

    2005-01-01

    Upgradering av biogas med tekniken vattenabsorption är vanligt i Sverige. Elva biogasanläggningar med tillsammans fjorton uppgraderingsanläggningar använder sig av tekniken. Problem med igensättning av fyllkroppar i absorptionskolonnen, samt i ett fall i desorptionskolonnen är vanligt förekommande och har en negativ effekt på uppgraderingen av rågas till fordonsgas. Fem av de nio anläggningarna i denna studie har problem med mikrobiell tillväxt på fyllkropparna. Syftet med denna rapport var a...

  9. Preventing microbial growth on pall-rings when upgrading biogas using absorption with water wash

    Energy Technology Data Exchange (ETDEWEB)

    Haakansson, Anna

    2006-07-15

    For produced biogas to be usable as vehicle fuel it has to be upgraded to a higher energy content. This is accomplished by elevation of the methane concentration through removal of carbon dioxide. Absorption with water wash is the most common upgrading method used in Sweden today. The upgrading technique is based on the fact that carbon dioxide is more soluble in water than methane. Upgrading plants that utilises this method have problems with microbial growth in the system. This growth eventually leads to a stop in operation due to the gradually drop in upgrading capacity. The aim of this thesis were to evaluate the possibility to through some kind of water treatment maintain an acceptable level of growth or altogether prevent it in order to maintain an acceptable process capacity and thereby avoid the need to clean. Through collection of literature the implementation possibilities were evaluated with regard to efficiency, economic sustainability and if there would be a release of any harmful substances. In order to prevent the microbial growth in the columns the treatment should either focus on removing microorganisms or limit the accessible nutrients. For the single pass system it is concluded that the treatment should reduce the biofilm formation and be employed in an intermittent way. Among the evaluated treatments focusing on the reduction of microorganisms the addition of peracetic acid seems to be the most promising one. For the regenerating system the treatment method could focus on either one. As for the single pass system peracetic acid could be added to reduce the amount of microorganism. To reduce the amount of organic matter an advanced oxidation process could be deployed with the advantage that it also could remove the microorganisms.

  10. Wexler's Great Smoke Pall: a chemistry-climate model analysis of a singularly large emissions pulse

    Science.gov (United States)

    Field, R. D.; Voulgarakis, A.

    2011-12-01

    We model the effects of the smoke plume from what was arguably the largest forest fire in recorded history. The Chinchaga fire burned continuously during the summer of 1950 in northwestern Canada during a very dry fire season. On September 22nd, the fire made a major advance, burning an area of approximately 1400 km2. Ground and aircraft observations showed that from September 22 to 28, the smoke plume from the emissions pulse travelled over northern Canada, southward over the Great Lakes region and eastern US, across the Atlantic, and to Western Europe. Over the Great Lakes region, the plume remained thick enough to create twilight conditions in the mid-afternoon, and was estimated to have caused a 4 oC cooling at the surface. While many instances of long-range transport of wildfire emissions have been detected over the past decade, we know of no other wildfire which created such an acute effect on downward shortwave radiation at such a long distance. As a result, the fire was an important analogue event used in estimating the effects of a nuclear winter. Simulations with the nudged version of the GISS chemistry-climate model accurately capture the long-range transport pattern of the smoke emissions in the free-troposphere. The timing and location of aircraft observations of the plume over the eastern US, North Atlantic and the United Kingdom were well-matched to modeled anomalies of CO and aerosol optical depth. Further work will examine the model's ability to create twilight conditions during the day, and to provide an estimate of the consequent cooling effects at the surface from this remarkable emissions pulse.

  11. Phenolic Compounds from Halimodendron halodendron (Pall. Voss and Their Antimicrobial and Antioxidant Activities

    Directory of Open Access Journals (Sweden)

    Jihua Wang

    2012-09-01

    Full Text Available Halimodendron halodendron has been used as forage in northwestern China for a long time. Its young leaves and flowers are edible and favored by indigenous people. In this study, eleven phenolic compounds were bioassay-guided and isolated from the aerial parts of H. halodendron for the first time. They were identified by means of physicochemical and spectrometric analysis as quercetin (1, 3,5,7,8,4'-pentahydroxy-3'-methoxy flavone (2, 3-O-methylquercetin (3, 3,3'-di-O-methylquercetin (4, 3,3'-di-O-methylquercetin-7-O-β-D-glucopyranoside (5, isorhamentin-3-O-β-D-rutinoside (6, 8-O-methylretusin (7, 8-O-methylretusin-7-O-β-D-glucopyranoside (8, salicylic acid (9, p-hydroxybenzoic acid (ferulic acid (10, and 4-hydroxy-3-methoxy cinnamic acid (11. They were sorted as flavonols (1–6, soflavones (7 and 8, and phenolic acids (9–11. Among the compounds, flanools 1–4 revealed a strong antibacterial activity with minimum inhibitory concentration (MIC values of 50–150 μg/mL, and median inhibitory concentration (IC50 values of 26.8–125.1 μg/mL. The two isoflavones (7 and 8 showed moderate inhibitory activity on the test bacteria. Three phenolic acids (9, 10 and 11 showed strong antibacterial activity with IC50 values of 28.1–149.7 μg/mL. Antifungal activities of the compounds were similar to their antibacterial activities. All these phenolic compounds showed significant antimicrobial activity with a broad spectrum as well as antioxidant activity based on 1,1-diphenyl-2-picrylhydrazyl (DPPH radical scavenging and β-carotene-linoleic acid bleaching assays. In general, the flavonol aglycones with relatively low polarity exhibited stronger activities than the glycosides. The results suggest the potential of this plant as a source of functional food ingredients and provide support data for its utilization as forage as well.

  12. СРАВНИТЕЛЬНАЯ МОРФОЛОГИЧЕСКАЯ ХАРАКТЕРИСТИКА СЕВРЮГИ ( АCIPENSER STELLATUS PALL.) ИЗ ПРИРОДНОЙ И АКВАКУЛЬТУРНОЙ ПОПУЛЯЦИИ

    OpenAIRE

    Шишанова, Елена; Кавтаров, Джавад

    2015-01-01

    Морфометрические исследования являются основополагающими при начале работы по одомашниванию новых видов рыб. Цель исследований сравнить морфологическую изменчивость севрюги ( Аcipenser stellatus Pall.), выращенной в условиях замкнутого водоснабжения, и природной северо-каспийской севрюги для оценки влияния индустриальных условий выращивания на ее морфотип. Впервые проведено сравнительное исследование 103 экз. половозрелой природной северо-каспийской севрюги и 50 экз. шестилеток аквакультурной...

  13. Penguin contributions to CP phases in $B_{d,s}$ decays to charmonium

    CERN Document Server

    Frings, Philipp; Wiebusch, Martin

    2015-01-01

    The precision of the CP phases $2\\beta$ and $2\\beta_s$ determined from the mixing-induced CP asymmetries in $B_d\\to J/\\psi K_S$ and $B_s\\to J/\\psi \\phi$, respectively, is limited by the unknown long-distance contribution of a penguin diagram involving up quarks. We analyze the infrared QCD structure of this contribution and find that all soft and collinear divergences either cancel between different diagrams or factorize into matrix elements of local four-quark operators up to terms suppressed by $\\Lambda_{QCD}/m_{\\psi}$, where $m_{\\psi}$ denotes the $J/\\psi$ mass. Our results allow us to calculate the penguin-to-tree ratio $P/T$ in terms of the matrix elements of these operators and to constrain the penguin contribution to the phase $2\\beta$ as $|\\Delta \\phi_d|\\leq {0.68}^\\circ$. The penguin contribution to $2\\beta_s$ is bounded as $|\\Delta \\phi_s^{0}|\\leq {1.03}^\\circ$, $|\\Delta \\phi_s^{\\parallel}|\\leq {1.28}^\\circ$, and $|\\Delta \\phi_s^{\\perp}|\\leq {0.95}^\\circ$ for the case of longitudinal, parallel, and ...

  14. Z-mediated charge and CP asymmetries and FCNCs in $B_{d,s}$ processes

    CERN Document Server

    Chen, Chuan-Hung; Wang, Wei

    2010-01-01

    We show model-independently that the upper bound for the negative like-sign charge asymmetry $(-A^b_{s\\ell})$ is $ (3.16_{-0.48}^{+0.49})\\times 10^{-3}$ when the constraints from the $B_q-\\bar B_q$ mixings and the time-dependent CP asymmetries (CPAs) for $B_q\\to J/\\Psi M_q$ with $M_q=K,\\phi$ and $q=d,s$ are taken into account. Although the upper bound is smaller than the measured value by the D{\\O} Collaboration at Fermilab, it is still one order of magnitude larger than the standard model (SM) prediction and sensitive to new CP violating effects. To illustrate the potential large $|A^{b}_{s\\ell}|$, we show the influence of new $SU(2)_L$ singlet exotic quarks in the vector-like quark model, where the $Z$-mediated flavor changing neutral currents (FCNCs) are generated at tree level. In particular, we demonstrate that (a) the like-sign charge asymmetry could be enhanced by a factor of two in magnitude; (b) the CPA of $\\sin2\\beta^{J/\\Psi \\phi}_s$ could reach to $-15\\%$; (c) the CPA of $\\sin2\\beta_{\\phi K_S}$ cou...

  15. Study of the decays B->D_s1(2536)+ anti-D(*)

    OpenAIRE

    Aushev, T.

    2011-01-01

    We report a study of the decays B -> D_s1(2536)+ anti-D(*), where anti-D(*) is anti-D0, D- or D*-, using a sample of 657 x 10^6 B anti-B pairs collected at the Upsilon(4S) resonance with the Belle detector at the KEKB asymmetric-energy e+e- collider. The branching fractions of the decays B+ -> D_s1(2536)+ anti-D0, B0 -> D_s1(2536)+ D- and B0 -> D_s1(2536)+ D*- multiplied by that of D_s1(2536)+ -> (D*0K+ + D*+K0) are found to be (3.97+-0.85+-0.56) x 10^-4, (2.75+-0.62+-0.36) x 10^-4 and (5.01+...

  16. Effect of Calcium Sprays on Mechanical Strength and Cell Wall Fractions of Herbaceous Peony (Paeonia Lactiflora Pall. Inflorescence Stems

    Directory of Open Access Journals (Sweden)

    Jintao Ge

    2012-04-01

    Full Text Available Calcium is an essential element and imparts significant structural rigidity to the plant cell walls, which provide the main mechanical support to the entire plant. In order to increase the mechanical strength of the inflorescence stems of herbaceous peony, the stems are treated with calcium chloride. The results shows that preharvest sprays with 4% (w/v calcium chloride three times after bud emergence are the best at strengthening “Da Fugui” peonies’ stems. Calcium sprays increased the concentrations of endogenous calcium, total pectin content as well as cell wall fractions in herbaceous peonies stems, and significantly increased the contents of them in the top segment. Correlation analysis showed that the breaking force of the top segment of peonies’ stems was positively correlated with the ratio of water insoluble pectin to water soluble pectin (R = 0.673 as well as lignin contents (R = 0.926 after calcium applications.

  17. The invasion history, distribution and colour pattern forms of the harlequin ladybird beetle Harmonia axyridis (Pall. (Coleoptera, Coccinellidae in Slovakia, Central Europe

    Directory of Open Access Journals (Sweden)

    Ľubomír Panigaj

    2014-05-01

    Full Text Available The harlequin ladybird beetle Harmonia axyridis (Coleoptera, Coccinellidae has invaded and established in Slovakia. Following unintentional introduction in 2008, the spread of the alien coccinellid was very fast. By the end of 2009, it was recorded across the whole country, and by the end of 2012 it was widely distributed and common in various habitats, particularly gardens, orchards and urban areas, where it was most frequent on trees. The rate of eastward spread was approximately 200 km year-1, similar to the overall rate of spread in Europe. Between 2008 and 2012, the coccinellid was recorded in a total of 153 localities, in altitudes ranging from 98 to 1,250 m. Most records of this species were made in lowlands, hilly areas and valleys separating mountain ridges. However, it was only rarely documented in areas above 700 m a.s.l. The non-melanic colour form (f. succinea was dominant along alongitudinal transect including eight urban areas across Slovakia, with the frequency of melanic forms (f. spectabilis and f. conspicua together between 6.3 and 19.2% and a median equal to 10.5%. The invasion history and distribution of H. axyridis in Slovakia are discussed with regard to the time sequence of records, rate of spread, altitudinal distribution, anthropogenic dispersal, effective recording, proportion of melanic forms and other relevant aspects associated with the spread of this successful invader.

  18. 尼龙11/POE共混物的形态与力学性能%The Morphology and Mechanical Properties of PAll/POE Blends

    Institute of Scientific and Technical Information of China (English)

    郭云霞; 胡国胜; 李迎春; 杨云峰; 王志强

    2012-01-01

    采用动态力学分析(DMTA)和扫描电镜(SEM)等方法研究了相容剂乙烯辛烯共聚物接枝马来酸酐聚合物(POE-g-MAH)对尼龙11(PA11)共混体系力学性能及共混物形态的影响。结果表明,混合弹性体中m(POE-g-MAH)/m(POE)=2∶1时,PA11共混物的缺口冲击强度达到81.2 kJ/m^2;共混物缺口冲击强度对MAH接枝率敏感;加入混合弹性体,共混体系分子间的作用力增大,损耗峰向高温方向移动,Tg升高;PA11与POE各个共混体系的β松弛峰高显著低于纯PA11的,加入POE和POE-g-MAH可有效降低PA11的吸水性;POE-g-MAH可显著改善PA11/POE共混材料的相容性,使分散相尺寸减小,分布均匀,且材料缺口冲击强度显著增大。%The effect of maleic anhydride grafted polyolefin elastomer(POE-g-MAH) as compatilizer on the mechanical properties and morphology of polyamide 11(PA11)/POE blends was investigated using dynamic mechanical analysis(DMTA) and scanning electron microscope(SEM).The results show that when the ratio of POE-g-MAH and POE in mixed elastomer is 2:1,the notched impact strength of PA11 blends reaches 81.2 kJ/m2.The notched impact strength of blends is sensitive to MAH grafted rate.When mixed elastomer is added into PA11,the intermolecular forces of blends system increase and the loss peaks move to the high temperature which results in higher Tg.The β relaxation peak of each blends of PA11 and POE is significantly lower than that of pure PA11,which illustrates that POE and POE-g-MAH can effectively reduce water absorptivity of PA11.POE-g-MAH can improve the miscibility between PA11 and POE,decrease the particle size of dispersion phase and obviously increase the notched impact strength of these blends.

  19. Muusikamaailm : CPE Bachi käsikirjad tagasi Saksamaale. Täna uusooper Londonis. Theodorakise ooperid plaadil. David Golub lahkunud. Preemia Palle Mikkelborgile / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2001-01-01

    Ukraina nõustus tagastama Saksamaale C.P.E. Bachi muusikakäsikirjad, mis Nõukogude Liidu armee sealt II Maailmasõja ajal ära viis. Inglise Rahvusooperis lavastuvast D.Saweri ooperist "From Morning to Midnight". M.Theodorakise kolm ooperit (antiiktriloogia "Elektra", "Antigone" ja "Medeia") ilmusid seoses maestro 75. juubeliga kaheksal CD-plaadil. Lühidalt D.Golubist. Põhjamaade Nõukogu tänavuse muusikapreemia võitis P.Mikkelborg

  20. A model-independent analysis of final-state interactions in \\bar B_{d/s}^0 --> J/psi pi pi

    CERN Document Server

    Daub, J T; Kubis, B

    2015-01-01

    Exploiting $B$-meson decays for Standard Model tests and beyond requires a precise understanding of the strong final-state interactions that can be provided model-independently by means of dispersion theory. This formalism allows one to deduce the universal pion-pion final-state interactions from the accurately known $\\pi\\pi$ phase shifts and, in the scalar sector, a coupled-channel treatment with the kaon-antikaon system. In this work an analysis of the decays $\\bar B_d^0 \\to J/\\psi \\pi^+\\pi^-$ and $\\bar B_s^0 \\to J/\\psi \\pi^+\\pi^-$ is presented. We find very good agreement with the data up to 1.05 GeV with a number of parameters reduced significantly compared to a phenomenological analysis. In addition, the phases of the amplitudes are correct by construction, a crucial feature when it comes to studies of $CP$ violation in heavy-meson decays.

  1. Evaluation of tooth preparations for Class II cavities using magnification loupes among dental interns and final year BDS students in preclinical laboratory

    Directory of Open Access Journals (Sweden)

    Khyati Narula

    2015-01-01

    Conclusions: Magnifying loupes help the dental students to have better vision, thus improved dexterity with hands while preparing the tooth for restoration. However, dental students have to get adapted to the loupes for the ease of using loupes. Using loupes frequently may help them to get adapted to the loupes.

  2. Effects of Harvest Stage on Ornamental Quality of Cut Flow ers of Herbaceous Peony (Paeonia lacti f lora Pall .)%采收期对芍药切花保鲜效果的影响

    Institute of Scientific and Technical Information of China (English)

    高水平; 魏春梅; 王焰; 吕明; 范丙友

    2013-01-01

    It is one of the most critical postharvest technologies to harvest cut herbaceous peony flowers at most suitable developmental stages .Using herbaceous peony cv .‘Xishimian’ as materi-als ,the effects of developmental stages on the vase life ,the opening life ,the flower diameter ,and the fresh weight loss rate were analyzed in order to ascertain the most suitable harvest stage for herbaceous peony .The result showed that the vase life and the opening life of cut herbaceous peo-ny flowers harvested at stage Ⅱ (Unfold-petal stage) were longer than at stages Ⅲ (Changing-color stage) and Ⅳ (Soft-bud stage) .Although the flower diameters of cut flower harvested at stage Ⅱ were smaller than at stages Ⅲ and Ⅳ ,the ornamental quality was not reduced signifi-cantly .Preservation solution (2% sucrose+200 mg/L 8-HQ+1 mol/L STS) had a good effect on flower diameter and reduced the fresh weight loss rate for herbaceous peony cv .‘Xishimian’ .%适期采收是芍药切花采后保鲜的关键技术。为确定芍药切花的最适采收期,以西施面芍药为材料,研究了采收期对芍药切花的瓶插寿命、开放寿命、切花花径、鲜质量损失率的影响。结果表明,Ⅱ级(松瓣期)采收的芍药切花瓶插寿命及开放寿命均优于Ⅲ(转色期)和Ⅳ级(暄蕾期)花,尽管切花花径略小于Ⅲ和Ⅳ级花,但其观赏价值并未明显降低;保鲜液(2%蔗糖+200 m g/L 8羟基喹啉+1 mol/L硫代硫酸银)对于增大切花花径、延缓并减少切花鲜质量损失具有一定促进作用。

  3. Full sun-spay-cutting method of Rosa Davurica Pall ' twig cutting%全光雾喷法在刺玫果嫩枝扦插上的应用

    Institute of Scientific and Technical Information of China (English)

    周军方; 段进潮; 徐岩; 任跃英; 王远亮; 肖兴利; 王秀萍

    2011-01-01

    全光雾喷法扦插育苗是近几年应用较多的快速育苗技术,它具有生根快、繁殖率高的特点,是快速繁殖优良品种苗木的一条重要途径。笔者对刺玫果分别用普通扦插和全光雾喷法进行夏季嫩枝扦插试验,结果表明用浓度为2×10-5g/mL的IBA浸泡16小时处理的插穗使用全光雾插法生根率可高达96%。%Full sun-spay-cutting method is the most applied on rapid seedling technique in recent years, its characteristic takes root quickly and reproductive rate high. It is important way of good varieties 'rapid propagation. By using chemical treatments of IBA on twig cuttings under common cutting and the full sun-spay-cutting method for summer cuttings test .The results show that adopted full sun-spay-eutting method ,which was cutting stems in summer, dousing in 2×10-5g/mL IBA for 16 hours .The rooting rate could reach 96%.

  4. 叶底珠各部位中一叶荻碱和别一叶荻碱的含量测定%Content determination of securinine and allosecurinine from every section of Securinega suffruticosa(Pall.)Rehd.

    Institute of Scientific and Technical Information of China (English)

    吕海花; 李雪晴; 王冉冉; 徐凌川

    2016-01-01

    采用高效液相色谱法测定叶底珠中一叶荻碱和别一叶荻碱在各部位中的含量.结果表明,一叶获碱在各部位的质量分数w根皮>w细根>w枝干皮>w木部>w嫩叶芽(济南)>w枝叶>w根>w嫩叶芽(临沂).别一叶荻碱在各部位的质量分数w根皮>w细根>w木部>w枝干皮>w根>w嫩叶芽(临沂)>w嫩叶芽(济南)>w枝叶.本实验为叶底珠生药成分中一叶荻碱和别一叶荻碱的定性和定量测定提供了科学依据.

  5. Extraction and Separation of Vitisin D, Ampelopsin B and cis-Vitisin A from Iris lactea Pall. var. chinensis (Fisch.) Koidz by Alkaline Extraction-Acid Precipitation and High-Speed Counter-Current Chromatography.

    Science.gov (United States)

    Lv, Huanhuan; Zhou, Wenna; Wang, Xiaoyan; Wang, Zhenhua; Suo, Yourui; Wang, Honglun

    2016-01-01

    Naturally occurring oligostilbenes are receiving more attention because they exhibit several beneficial effects for health, including hepatoprotective, antitumor, anti-adipogenic, antioxidant, antiaging, anti-inflammatory, anti-microbial, antiviral, immunosuppressive and neuroprotective activities. Thus, they could be of some potentially therapeutic values for several diseases. In this study, we adopted the alkaline extraction-acid precipitation (AEAP) method for extraction of oligostilbenes from the seed kernel of Iris lactea Then, the high-speed counter-current chromatography (HSCCC) was used for preparative isolation and purification of oligostilbenes from the AEAP extracts. Finally, three oligostilbenes, namely vitisin D (73 mg), ampelopsin B (25 mg) and cis-vitisin A (16 mg), were successfully fractionated by HSCCC with a two-phase solvent system composed of n-hexane-ethyl acetate-methanol-water (2:5:3:6, v/v/v/v) from 300 mg of the AEAP extracts in ∼ 190 min. The purities of the three isolated oligostilbenes were all over 95.0% as analyzed by high performance liquid chromatography. They all were isolated from I. lacteal for the first time.The method of AEAP for the preparation of the oligostilbene-enriched crude sample was simple, and the HSCCC technique for the isolation and purification of oligostilbenes was efficient. PMID:26847919

  6. Electric energy forecast by using Arma, Nara, Polynomial and Pall models: a comparative study; Predicao de demanda de energia eletrica utilizando modelos Arma, Narma, polinomial e PLL: um estudo comparativo

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Viviane Cota; Furtado, Edgar Campos; Aguirre, Luiz Antonio [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Programa de Pos-Graduacao em Engenharia Eletrica (PGEE)]. E-mails: vivianne@cpdee.ufmg.br; edgar@cpdee.ufmg.br; aguirre@cpdee.ufmg.br; Correa, Marcelo Vieira [Centro Universitario do Leste de Minas Gerais, Coronel Fabriciano, MG (Brazil)]. E-mail: mcorrea@unilestemg.br

    2004-07-01

    This work presents a case study for the short term electric power demand prediction testing three types of mathematical models: the Aroma, the polynomial Nara, and the Local Linear Predictor - Lp already used in other case studies, with time schedule established for the prediction as 8 hours ahead. The work is stimulated by the need to obtain good predictors for the electric energy demand, as the short term load prediction is very important for the electric power enterprises. The results obtained with the studying data demonstrate most suitability of the Nam polynomial model when compared to the LLP model in the prediction of electric energy demand.

  7. 白芍多糖的制备、理化性质及抗肿瘤活性研究%Studies on Preparation, Physicochemical Properties and Antitumor Activity of Polysaccharide from the Root of Paeonia lactiflora Pall.

    Institute of Scientific and Technical Information of China (English)

    汪芸; 陶移文; 田庚元

    2013-01-01

    目的:研究中药白芍中多糖的制备、理化性质及对小鼠路易斯肺癌和S180肉瘤的抗肿瘤活性.方法:采用水提醇沉方法提取白芍中多糖(BSEP),测定其糖和糖醛酸含量、元素组成、单糖组成;同时采用小鼠路易斯肺癌足趾皮下接种模型和S180肉瘤腋皮下接种模型考察BSEP的抗肿瘤活性.结果:BSEP的提取率分别为1.56%,糖含量为80.56%,糖醛酸含量为3.33%,单糖组成分析为91.7%的葡萄糖,4.19%的半乳糖以及2.83%的阿拉伯糖.生物活性表明BSEP样品分别以200,100mg·kg-1剂量ip×10qd的治疗方案,对小鼠体内路易斯肺癌足趾接种模型的肿瘤抑制率分别为54.58%和43.33%,对小鼠S180肉瘤皮下接种模型的肿瘤抑制率分别为47.08%和38.98%.结论:BSEP是主要以葡萄糖组成,且含有少量糖醛酸的多糖,具有一定的抗肿瘤活性,对小鼠路易斯肺癌的疗效稍优于S180肉瘤模型.

  8. Hi-C Observations of Penumbral Bright Dots

    Science.gov (United States)

    Alpert, S. E.; Tiwari, S. K.; Moore, R. L.; Savage, S. L.; Winebarger, A. R.

    2014-01-01

    We use high-quality data obtained by the High Resolution Coronal Imager (Hi-C) to examine bright dots (BDs) in a sunspot's penumbra. The sizes of these BDs are on the order of 1 arcsecond (1") and are therefore hard to identify using the Atmospheric Imaging Assembly's (AIA) 0.6" pixel(exp -1) resolution. These BD become readily apparent with Hi-C's 0.1" pixel(exp -1) resolution. Tian et al. (2014) found penumbral BDs in the transition region (TR) by using the Interface Region Imaging Spectrograph (IRIS). However, only a few of their dots could be associated with any enhanced brightness in AIA channels. In this work, we examine the characteristics of the penumbral BDs observed by Hi-C in a sunspot penumbra, including their sizes, lifetimes, speeds, and intensity. We also attempt to find any association of these BDs to the IRIS BDs. There are fewer Hi-C BDs in the penumbra than seen by IRIS, though different sunspots were studied. We use 193 Angstroms Hi-C data from July 11, 2012 which observed from approximately 18:52:00 UT- 18:56:00 UT and supplement it with data from AIA's 193 Angstrom passband to see the complete lifetime of the dots that were born before and/or lasted longer than Hi- C's 5-minute observation period. We use additional AIA passbands and compare the light curves of the BDs at different temperatures to test whether the Hi-C BDs are TR BDs. We find that most Hi-C BDs show clear movement, and of those that do, they move in a radial direction, toward or away from the sunspot umbra. Single BDs interact with other BDs, combining to fade away or brighten. The BDs that do not interact with other BDs tend to move less. Many of the properties of our BDs are similar to the extreme values of the IRIS BDs, e.g., they move slower on average and their sizes and lifetimes are on the higher end of the IRIS BDs. We infer that our penumbral BDs are the large-scale end of the distribution of BDs observed by IRIS.

  9. Papers

    DEFF Research Database (Denmark)

    Thoft-Christensen, Palle

    The chapters in this Volume 7 of a series of PAPERS are based on papers published in the period 2004 - 2008 authored/co-authored by Palle Thoft-Christensen......The chapters in this Volume 7 of a series of PAPERS are based on papers published in the period 2004 - 2008 authored/co-authored by Palle Thoft-Christensen...

  10. Hi-C Observations of Sunspot Penumbral Bright Dots

    CERN Document Server

    Alpert, Shane E; Moore, Ronald L; Winebarger, Amy R; Savage, Sabrina L

    2016-01-01

    We report observations of bright dots (BDs) in a sunspot penumbra using High Resolution Coronal Imager (Hi-C) data in 193 \\AA\\ and examine their sizes, lifetimes, speeds, and intensities. The sizes of the BDs are on the order of 1\\arcsec\\ and are therefore hard to identify in the Atmospheric Imaging Assembly (AIA) 193 \\AA\\ images, which have 1.2\\arcsec\\ spatial resolution, but become readily apparent with Hi-C's five times better spatial resolution. We supplement Hi-C data with data from AIA's 193 \\AA\\ passband to see the complete lifetime of the BDs that appeared before and/or lasted longer than Hi-C's 3-minute observation period. Most Hi-C BDs show clear lateral movement along penumbral striations, toward or away from the sunspot umbra. Single BDs often interact with other BDs, combining to fade away or brighten. The BDs that do not interact with other BDs tend to have smaller displacements. These BDs are about as numerous but move slower on average than Interface Region Imaging Spectrograph (IRIS) BDs, rec...

  11. Assessment of the Contribution of BeiDou GEO, IGSO, and MEO Satellites to PPP in Asia—Pacific Region

    Directory of Open Access Journals (Sweden)

    Qile Zhao

    2015-12-01

    Full Text Available In contrast to the US Global Positioning System (GPS, the Russian Global Navigation Satellite System (GLONASS and the European Galileo, the developing Chinese BeiDou satellite navigation system (BDS consists of not only Medium Earth Orbit (MEO, but also Geostationary Orbit (GEO as well as Inclined Geosynchronous Orbit (IGSO satellites. In this study, the Precise Point Positioning (PPP and PPP with Integer Ambiguity Resolution (IAR are obtained. The contributions of these three different types of BDS satellites to PPP in Asia-Pacific region are assessed using data from selected 20 sites over more than four weeks. By using various PPP cases with different satellite combinations, in general, the largest contribution of BDS IGSO among the three kinds of BDS satellites to the reduction of convergence time and the improvement of positioning accuracy, particularly in the east direction, is identified. These PPP cases include static BDS only solutions and static/kinematic ambiguity-float and -fixed PPP with the combination of GPS and BDS. The statistical results demonstrate that the inclusion of BDS GEO and MEO satellites can improve the observation condition and result in better PPP performance as well. When combined with GPS, the contribution of BDS to the reduction of convergence time is, however, not as significant as that of GLONASS. As far as the positioning accuracy is concerned, GLONASS improves the accuracy in vertical component more than BDS does, whereas similar improvement in horizontal component can be achieved by inclusion of BDS IGSO and MEO as GLONASS.

  12. Ambiguity resolved precise point positioning with GPS and BeiDou

    Science.gov (United States)

    Pan, Li; Xiaohong, Zhang; Fei, Guo

    2016-07-01

    This paper focuses on the contribution of the global positioning system (GPS) and BeiDou navigation satellite system (BDS) observations to precise point positioning (PPP) ambiguity resolution (AR). A GPS + BDS fractional cycle bias (FCB) estimation method and a PPP AR model were developed using integrated GPS and BDS observations. For FCB estimation, the GPS + BDS combined PPP float solutions of the globally distributed IGS MGEX were first performed. When integrating GPS observations, the BDS ambiguities can be precisely estimated with less than four tracked BDS satellites. The FCBs of both GPS and BDS satellites can then be estimated from these precise ambiguities. For the GPS + BDS combined AR, one GPS and one BDS IGSO or MEO satellite were first chosen as the reference satellite for GPS and BDS, respectively, to form inner-system single-differenced ambiguities. The single-differenced GPS and BDS ambiguities were then fused by partial ambiguity resolution to increase the possibility of fixing a subset of decorrelated ambiguities with high confidence. To verify the correctness of the FCB estimation and the effectiveness of the GPS + BDS PPP AR, data recorded from about 75 IGS MGEX stations during the period of DOY 123-151 (May 3 to May 31) in 2015 were used for validation. Data were processed with three strategies: BDS-only AR, GPS-only AR and GPS + BDS AR. Numerous experimental results show that the time to first fix (TTFF) is longer than 6 h for the BDS AR in general and that the fixing rate is usually less than 35 % for both static and kinematic PPP. An average TTFF of 21.7 min and 33.6 min together with a fixing rate of 98.6 and 97.0 % in static and kinematic PPP, respectively, can be achieved for GPS-only ambiguity fixing. For the combined GPS + BDS AR, the average TTFF can be shortened to 16.9 min and 24.6 min and the fixing rate can be increased to 99.5 and 99.0 % in static and kinematic PPP, respectively. Results also show that GPS + BDS PPP AR outperforms

  13. Real-time retrieval of precipitable water vapor from GPS and BeiDou observations

    Science.gov (United States)

    Lu, Cuixian; Li, Xingxing; Nilsson, Tobias; Ning, Tong; Heinkelmann, Robert; Ge, Maorong; Glaser, Susanne; Schuh, Harald

    2015-09-01

    The rapid development of the Chinese BeiDou Navigation Satellite System (BDS) brings a promising prospect for the real-time retrieval of zenith tropospheric delays (ZTD) and precipitable water vapor (PWV), which is of great benefit for supporting the time-critical meteorological applications such as nowcasting or severe weather event monitoring. In this study, we develop a real-time ZTD/PWV processing method based on Global Positioning System (GPS) and BDS observations. The performance of ZTD and PWV derived from BDS observations using real-time precise point positioning (PPP) technique is carefully investigated. The contribution of combining BDS and GPS for ZTD/PWV retrieving is evaluated as well. GPS and BDS observations of a half-year period for 40 globally distributed stations from the International GNSS Service Multi-GNSS Experiment and BeiDou Experiment Tracking Network are processed. The results show that the real-time BDS-only ZTD series agree well with the GPS-only ZTD series in general: the RMS values are about 11-16 mm (about 2-3 mm in PWV). Furthermore, the real-time ZTD derived from GPS-only, BDS-only, and GPS/BDS combined solutions are compared with those derived from the Very Long Baseline Interferometry. The comparisons show that the BDS can contribute to real-time meteorological applications, slightly less accurately than GPS. More accurate and reliable water vapor estimates, about 1.3-1.8 mm in PWV, can be obtained if the BDS observations are combined with the GPS observations in the real-time PPP data processing. The PWV comparisons with radiosondes further confirm the performance of BDS-derived real-time PWV and the benefit of adding BDS to standard GPS processing.

  14. Evaluation of the efficiency of biofield diagnostic system in breast cancer detection using clinical study results and classifiers.

    Science.gov (United States)

    Subbhuraam, Vinitha Sree; Ng, E Y K; Kaw, G; Acharya U, Rajendra; Chong, B K

    2012-02-01

    The division of breast cancer cells results in regions of electrical depolarisation within the breast. These regions extend to the skin surface from where diagnostic information can be obtained through measurements of the skin surface electropotentials using sensors. This technique is used by the Biofield Diagnostic System (BDS) to detect the presence of malignancy. This paper evaluates the efficiency of BDS in breast cancer detection and also evaluates the use of classifiers for improving the accuracy of BDS. 182 women scheduled for either mammography or ultrasound or both tests participated in the BDS clinical study conducted at Tan Tock Seng hospital, Singapore. Using the BDS index obtained from the BDS examination and the level of suspicion score obtained from mammography/ultrasound results, the final BDS result was deciphered. BDS demonstrated high values for sensitivity (96.23%), specificity (93.80%), and accuracy (94.51%). Also, we have studied the performance of five supervised learning based classifiers (back propagation network, probabilistic neural network, linear discriminant analysis, support vector machines, and a fuzzy classifier), by feeding selected features from the collected dataset. The clinical study results show that BDS can help physicians to differentiate benign and malignant breast lesions, and thereby, aid in making better biopsy recommendations.

  15. Estimation of differential code biases for Beidou navigation system using multi-GNSS observations: How stable are the differential satellite and receiver code biases?

    Science.gov (United States)

    Xue, Junchen; Song, Shuli; Zhu, Wenyao

    2016-04-01

    Differential code biases (DCBs) are important parameters that must be estimated accurately and reliably for high-precision GNSS applications. For optimal operational service performance of the Beidou navigation system (BDS), continuous monitoring and constant quality assessment of the BDS satellite DCBs are crucial. In this study, a global ionospheric model was constructed based on a dual system BDS/GPS combination. Daily BDS DCBs were estimated together with the total electron content from 23 months' multi-GNSS observations. The stability of the resulting BDS DCB estimates was analyzed in detail. It was found that over a long period, the standard deviations (STDs) for all satellite B1-B2 DCBs were within 0.3 ns (average: 0.19 ns) and for all satellite B1-B3 DCBs, the STDs were within 0.36 ns (average: 0.22 ns). For BDS receivers, the STDs were greater than for the satellites, with most values STD between 28- and 7-day intervals was small, with a maximum not exceeding 0.06 ns. In almost all cases, the difference in BDS satellite DCBs between two consecutive days was <0.8 ns. The main conclusion is that because of the stability of the BDS DCBs, they only require occasional estimation or calibration. Furthermore, the 30-day averaged satellite DCBs can be used reliably for the most demanding BDS applications.

  16. Astrophysics of brown dwarfs; Proceedings of the Workshop, George Mason University, Fairfax, VA, Oct. 14, 15, 1985

    Science.gov (United States)

    Kafatos, Minas C. (Editor); Harrington, Robert S. (Editor); Maran, Stephen P. (Editor)

    1986-01-01

    Various reports on theoretical and observational studies of brown dwarfs (BDs) are presented. The topics considered include: astrometric detection of BDs, search for substellar companions to nearby stars using IR imaging, constraints on BD mass function from optical and IR searches, properties of stellar objects near the main sequence mass limit, search for low-mass stellar companions with the HF precision velocity technique, dynamical search for substellar objects, search for BDs in the IRAS data base, deep CCD survey for low mass stars in the disk and halo, the Berkeley search for a faint solar companion, the luminosity function for late M stars, astronomic search for IR dwarfs, and the role of the Space Telescope in the detection of BDs. Also addressed are: theoretical significance of BDs, evolution of super-Jupiters, compositional indicators in IR spectra of BDs, evolution of BDs and the evolutionary status of VB8B, the position of BDs on universal diagrams, theoretical determination of the minimum protostellar mass, Population II BDs and dark halos.

  17. Evaluation of the efficiency of biofield diagnostic system in breast cancer detection using clinical study results and classifiers.

    Science.gov (United States)

    Subbhuraam, Vinitha Sree; Ng, E Y K; Kaw, G; Acharya U, Rajendra; Chong, B K

    2012-02-01

    The division of breast cancer cells results in regions of electrical depolarisation within the breast. These regions extend to the skin surface from where diagnostic information can be obtained through measurements of the skin surface electropotentials using sensors. This technique is used by the Biofield Diagnostic System (BDS) to detect the presence of malignancy. This paper evaluates the efficiency of BDS in breast cancer detection and also evaluates the use of classifiers for improving the accuracy of BDS. 182 women scheduled for either mammography or ultrasound or both tests participated in the BDS clinical study conducted at Tan Tock Seng hospital, Singapore. Using the BDS index obtained from the BDS examination and the level of suspicion score obtained from mammography/ultrasound results, the final BDS result was deciphered. BDS demonstrated high values for sensitivity (96.23%), specificity (93.80%), and accuracy (94.51%). Also, we have studied the performance of five supervised learning based classifiers (back propagation network, probabilistic neural network, linear discriminant analysis, support vector machines, and a fuzzy classifier), by feeding selected features from the collected dataset. The clinical study results show that BDS can help physicians to differentiate benign and malignant breast lesions, and thereby, aid in making better biopsy recommendations. PMID:20703753

  18. RECYCLING RECOVERED WOOD-BASED MATERIALS. FLATNESS, MOR AND MOE OF PANELS MADE FROM RECOVERED WOODEN BASED MATERIALS

    Directory of Open Access Journals (Sweden)

    Andrea DEÁK

    2015-12-01

    Full Text Available The objective of the research was to study the mechanical properties of recovered solid wood and wood-based materials, to create new panels made of strips of recovered oak and spruce wood, particleboards and blockboards and to study their mechanical properties, feasibility and use. Flatness, MOR and MOE were determined for the solid wood and wood-based materials recovered from construction and demolition sites. Four types of experimental panels (PL1, PL2, PALL1 and PALL2 were manufactured from solid wood strips alternating with either particleboard or blockboard strips glued edge to edge. Some of their physical and mechanical properties were investigated. All new panels made from recovered materials fell within allowable limits specified in European standard requirements for panel flatness. Panels type PL2, PALL1 and PALL2 show better values for MoR and MoE parallel to the grain when compared to the respective values for the recovered wood-based materials of which they are made, but panels type PL1 show no change. Panels type PALL2 are preferable to panels type PALL1 due to better mechanical properties. Panels type PL1 and PL2 show no such differences in their structure. The results also show that these new panels can be used successfully in furniture production, provided panels type PL1, PL2 ad PALL1 do not bear loads perpendicular to the grain or receive reinforcing elements.

  19. Fluorescent microscope observation on pollination compatibility of Ground cherry[Cerasus fruticosa (Pall.)]crossing with different cherry cultivars%草原樱桃种内和种间授粉亲和性的荧光显微观察

    Institute of Scientific and Technical Information of China (English)

    杨凤军; 臧忠婧; 吴瑕

    2015-01-01

    [目的]研究草原樱桃(Prunus fruticosa)与不同樱桃远缘杂交亲和性的关系.[方法]以草原樱桃为母本,采用自交、品种间杂交、远缘杂交(毛樱桃、中国樱桃和欧洲甜樱桃),不同时间进行取样,荧光显微镜观察花粉管萌发生长状况.[结果]1)草原樱桃存在自交不亲和现象,需要品种间杂交授粉结实.2)草原樱桃与毛樱桃远缘杂交表现为配子体不亲和;草原樱桃与中国樱桃远缘杂交亲和,结实率为10%~52%;草原樱桃与欧洲甜樱桃远缘杂交表现为孢子体不亲和.[结论]草原樱桃存在自交不亲和现象,与同属的不同种樱桃远缘杂交亲和性有显著差异.

  20. Uikala prügila sai puhastusseadmed / Külli Kriis

    Index Scriptorium Estoniae

    Kriis, Külli, 1961-

    2004-01-01

    Ilmunud ka: Severnoje Poberezhje, 22. mai 2004, lk. 3. 21. mail 2004 Ida-Virumaal Uikala prügilas avatud puhastusseadmete kompleksist, mille valmistas ja paigaldas rahvusvaheline ettevõte Pall Corporation

  1. Two New Antibacterial Iridoids from Patrinia rupestris

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Two new iridoids (1 and 2) were isolated from the roots of Patrinia rupestris (Pall.) Juss.Their structures were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited strong antibacterial activities against Eschecichia coli and Staphylococcus aureus, respectively.

  2. The hidden world within plants

    NARCIS (Netherlands)

    Hardoim, Pablo R.; Overbeek, Van Leonard S.; Berg, Gabriele; Pirttilä, Anna Maria; Compant, Stéphane; Campisano, Andrea; Döring, Matthias; Sessitsch, Angela

    2015-01-01

    <p>All plants are inhabited internally by diverse microbial communities comprising bacterial, archaeal, fungal, and protistic taxa. These microorganisms showing endophytic lifestyles play crucial roles in plant development, growth, fitness, and diversification. The increasing awareness of and inform

  3. Data mining approach to evaluating the use of skin surface electropotentials for breast cancer detection.

    Science.gov (United States)

    Sree, S Vinitha; Ng, E Y K; Acharya, U Rajendra

    2010-02-01

    The Biofield Diagnostic System (BDS) uses a score formed with measured skin surface electropotentials and a prior Level Of Suspicion (LOS) value (predicted by the physician based on the patient's ultrasound or mammography results) to calculate a revised Post-BDS LOS to indicate the presence of breast cancer. The demographic details, BDS test results, and the recorded electropotential values form a potentially useful dataset, which can be further explored with data mining tools to extract important information that can be used to improve the current predictive accuracy of the device. According to the proposed data mining framework, the BDS dataset with 291 cases was first pre-processed to remove outliers and then used to select relevant and informative features for classifier development and finally to evaluate the capability of the built classifiers in detecting the presence of the disease. Two popular feature selection techniques, namely, the filter and wrapper methods, were used in parallel for feature selection. A few statistical inference based classifiers and neural networks were used for classification. The proposed technique significantly improved the BDS prediction accuracy. Also, the use of prior LOS and, hence, the Post-BDS LOS, associates a mild subjective interpretation to the current prediction methodology used by BDS. However, the feature subset selected in our analysis that gave the best accuracy did not use either of these features. This result indicates the possibility of using BDS as a better objective assessment tool for breast cancer detection.

  4. 77 FR 18270 - Acceptance Decision for the Unrestricted Use of the Former Michigan Chemical Company-Breckenridge...

    Science.gov (United States)

    2012-03-27

    ...-earth oxides at the St. Louis plant generated a dense, clay-like waste known as ``filter cake,'' which... radioactive filter cake was buried at the BDS. Burial of the filter cake at the BDS was permitted under AEC license number SMB-00833 and regulations in effect at the time. After the filter cake was buried, the...

  5. Data mining approach to evaluating the use of skin surface electropotentials for breast cancer detection.

    Science.gov (United States)

    Sree, S Vinitha; Ng, E Y K; Acharya, U Rajendra

    2010-02-01

    The Biofield Diagnostic System (BDS) uses a score formed with measured skin surface electropotentials and a prior Level Of Suspicion (LOS) value (predicted by the physician based on the patient's ultrasound or mammography results) to calculate a revised Post-BDS LOS to indicate the presence of breast cancer. The demographic details, BDS test results, and the recorded electropotential values form a potentially useful dataset, which can be further explored with data mining tools to extract important information that can be used to improve the current predictive accuracy of the device. According to the proposed data mining framework, the BDS dataset with 291 cases was first pre-processed to remove outliers and then used to select relevant and informative features for classifier development and finally to evaluate the capability of the built classifiers in detecting the presence of the disease. Two popular feature selection techniques, namely, the filter and wrapper methods, were used in parallel for feature selection. A few statistical inference based classifiers and neural networks were used for classification. The proposed technique significantly improved the BDS prediction accuracy. Also, the use of prior LOS and, hence, the Post-BDS LOS, associates a mild subjective interpretation to the current prediction methodology used by BDS. However, the feature subset selected in our analysis that gave the best accuracy did not use either of these features. This result indicates the possibility of using BDS as a better objective assessment tool for breast cancer detection. PMID:20082535

  6. Bromodomain and extra-terminal (BET) family proteins: New therapeutic targets in major diseases

    Indian Academy of Sciences (India)

    Balasundaram Padmanabhan; Shruti Mathur; Manjula Ramu; Shailesh Tripathi

    2016-06-01

    The bromodomains and extra-terminal domain (BET) family proteins recognize acetylated chromatin through their bromodomains (BDs) and helps in regulating gene expression. BDs are chromatin ‘readers’; by interacting with acetylated lysines on the histone tails, they recruit chromatin-regulating proteins on the promoter region to regulate gene expression and repression. Extensive efforts have been employed by the scientific communities worldwide, to identify and develop potential inhibitors of BET family BDs to regulate protein expression by inhibiting acetylated histone (H3/H4) interactions. Several small molecule inhibitors have been reported, which not only have high affinity, but also have high specificity to BET BDs. These developments make BET family proteins to be an important therapeutic targets, for major diseases such as cancer, neurological disorders, obesity and inflammation. Here, we review and discuss the structural biology of BET family BDs and their applications in major diseases.

  7. Assessment of precipitable water vapor derived from ground-based BeiDou observations with Precise Point Positioning approach

    Science.gov (United States)

    Li, Min; Li, Wenwen; Shi, Chuang; Zhao, Qile; Su, Xing; Qu, Lizhong; Liu, Zhizhao

    2015-01-01

    Precipitable water vapor (PWV) estimation from Global Positioning System (GPS) has been extensively studied and used for meteorological applications. However PWV estimation using the emerging BeiDou Navigation Satellite System (BDS) is very limited. In this paper the PWV estimation strategy and the evaluation of the results inferred from ground-based BDS observations using Precise Point Positioning (PPP) method are presented. BDS and GPS data from 10 stations distributed in the Asia-Pacific and West Indian Ocean regions during the year 2013 are processed using the PANDA (Position and Navigation Data Analyst) software package. The BDS-PWV and GPS-PWV are derived from the BDS-only and GPS-only observations, respectively. The PPP positioning differences between BDS-only and GPS-only show a standard deviation (STD) GPS-PWV at the HKTU station (Hong Kong, China) is compared with PWV derived from a radiosonde station (about 1 km distance) over a 6-month period. The GPS-PWV shows a good agreement with radiosonde-PWV with a bias of 0.002 mm and a STD of 2.49 mm while BDS-PWV has with a bias of -2.04 mm and STD 2.68 mm with respect to radiosonde-PWV. This indicates that the PWV estimated from the BDS can achieve similar precision as PWV from GPS. The BDS-PWV is compared to GPS-PWV at 10 stations. The mean bias and STD of their differences at 10 stations are 0.78 mm and 1.77 mm, respectively. The mean root mean square (RMS) value is 2.00 mm by considering the GPS-PWV as reference truth. This again confirms that the BDS-PWV has a good agreement with the GPS-PWV. It clearly indicates that the BDS is ready for the high precision meteorological applications in the Asia-Pacific and West Indian Ocean regions and that BDS alone can be used for PWV estimation with an accuracy comparable to GPS.

  8. Impact of salt stress on the features and activities of root system for three desert halophyte species in their seedling stage

    Institute of Scientific and Technical Information of China (English)

    YI LiangPeng; MA Jian; LI Yan

    2007-01-01

    Linkage between belowground and aboveground sections of ecological system is mainly depending on root system. But root system is the parts of plant that people less understand. The absorption function of root system is closely related to their morphology and activity. Moreover root system can interact with the environmental stress under the adverse situation, and adjust its system to take adaptation responses in morphology and physiology to strengthen its survival chance. This research is focused on three desert halophyte species of H. ammodendron (C.A.Mey.) Bge., S. physophora Pall., and S.nitraria Pall. under solution culture, to study the differences of their root system morphology and activity in the seedling stage under varying salt concentration conditions. The study results show that: A certain salt concentration can promote development of these three halophytes; but rather high salt concentration will restrain their growth, in particular inhibit the root system development. Under the same salt concentration condition, S. nitraria Pall. grows fast and accumulates the largest amount of biomass. Under relatively low salt concentration, the length of axial root and the total length of root system of these three halophyte species are all increased; and compared to the checking samples, S.physophora Pall. occupies the top place of root system growth, but the high salt concentration will restrain the increase of total root length; among them, the impact intensity on S. physophora Pall. is lighter than to H. ammodendron (C.A.Mey.) Bge. and S. nitraria Pall. is lighter; the salinity does not bring distinct influence on the average diameter of root system of these three plant species, but trends to reducing the size; under the solution culture conditions, the middle and lower parts of the axial root of H. ammodendron (C.A.Mey.) Bge. and S. physophora Pall. are rather equally distributed, but the central zone of S. nitraria Pall. root system is more significantly

  9. 5th China Satellite Navigation Conference

    CERN Document Server

    Jiao, Wenhai; Wu, Haitao; Lu, Mingquan

    2014-01-01

    China Satellite Navigation Conference (CSNC) 2014 Proceedings presents selected research papers from CSNC2014, held on 21-23 May in Nanjing, China. The theme of CSNC2014 is 'BDS Application: Innovation, Integration and Sharing'. These papers discuss the technologies and applications of the Global Navigation Satellite System (GNSS), and the latest progress made in the China BeiDou System (BDS) especially. They are divided into 9 topics to match the corresponding sessions in CSNC2014, which broadly covered key topics in GNSS. Readers can learn about the BDS and keep abreast of the latest advances in GNSS techniques and applications.  SUN Jiadong is the Chief Designer of the Compass/ BDS, and the Academician of Chinese Academy of Sciences (CAS); JIAO Wenhai is a researcher at China Satellite Navigation Office; WU Haitao is a professor at Navigation Headquarters, CAS; LU Mingquan is a professor at Department of Electronic Engineering of Tsinghua University.

  10. NCBI nr-aa BLAST: CBRC-PHAM-01-1276 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-PHAM-01-1276 sp|Q9BDS8|CCR3_MACFA RecName: Full=C-C chemokine receptor type 3; Short=C-C CKR-3; Short...=CC-CKR-3; Short=CCR-3; Short=CCR3; Short=CKR3; AltName: CD_antigen=CD193 gb|AAK25739.1| chemokine receptor CCR3 [Macaca fascicularis] Q9BDS8 0.0 97% ...

  11. Evaluation of Intervention on Voluntary Blood Donation among 1st Prof Medical and Dental Students of Index Medical College, Indore (MP), India

    OpenAIRE

    Abhishek Bachhotiya, V K Arora, Piyusha Mahashabde

    2014-01-01

    Objective: Objectives of this study was to assess KAP regarding voluntary blood donation among 1stprof MBBS & BDS students of Index Medical College, Indore and also to evaluate the intervention in making the students aware about voluntary blood donation Methods: Among 209 students (125 MBBS, 84 BDS) a questionnaire was administered followed by participants’ visit to the hospital blood donation centre where a short interactive awareness session was organized. The willingness to donate b...

  12. Factor structure and construct validity of the Behavioral Dyscontrol Scale-II.

    Science.gov (United States)

    Shura, Robert D; Rowland, Jared A; Yoash-Gantz, Ruth E

    2015-01-01

    The Behavioral Dyscontrol Scale-II (BDS-II) was developed as an improved scoring method to the original BDS, which was designed to evaluate the capacity for independent regulation of behavior and attention. The purpose of this study was to evaluate the factor structure and construct validity of the BDS-II, which had not been adequately re-examined since the development of the new scoring system. In a sample of 164 Veterans with a mean age of 35 years, exploratory factor analysis was used to evaluate BDS-II latent factor structure. Correlations and regressions were used to explore validity against 22 psychometrically sound neurocognitive measures across seven neurocognitive domains of sensation, motor output, processing speed, attention, visual-spatial reasoning, memory, and executive functions. Factor analysis found a two-factor solution for this sample which explained 41% of the variance in the model. Validity analyses found significant correlations among the BDS-II scores and all other cognitive domains except sensation and language (which was not evaluated). Hierarchical regressions revealed that PASAT performance was strongly associated with all three BDS-II scores; dominant hand Finger Tapping Test was also associated with the Total score and Factor 1, and CPT-II Commissions was also associated with Factor 2. These results suggest the BDS-II is both a general test of cerebral functioning, and a more specific test of working memory, motor output, and impulsivity. The BDS-II may therefore show utility with younger populations for measuring frontal lobe abilities and might be very sensitive to neurological injury. PMID:25650736

  13. Social Media Rhetoric of the Transnational Palestinian-led Boycott, Divestment, and Sanctions Movement

    Directory of Open Access Journals (Sweden)

    Jennifer Hitchcock

    2016-02-01

    Full Text Available This article uses rhetorical analysis to determine the effectiveness and characteristics of social media usage by the Boycott, Divestment, and Sanctions (BDS movement targeting Israel. Hundreds of local student, community, and religious groups in the United States use social media platforms such as Twitter and Facebook to promote BDS discourse and organize local BDS-related events. Even though social media platforms are important for an international movement composed of a very dispersed population, with millions of Palestinians also living under military occupation, the history of traditional media use during the First Intifada also suggests that social media are not necessary for mobilizing Palestinians at the local level. A preliminary rhetorical analysis of several BDS-related Facebook pages and Twitter accounts reveals that the BDS movement’s social media usage functions similarly in some ways to other contemporary mass movements by facilitating on-the-ground actions and delivering useful information to supporters. BDS movement social media discourse, however, does not establish the same level of emotional connection or interactivity with audiences as some other recent movements have, but these limitations can be partly explained by the unique political, material, and rhetorical constraints of the situation.

  14. Research and Realization of Deformation Monitoring Algorithm with Millimeter Level Precision Based on BeiDou Navigation Satellite System

    Directory of Open Access Journals (Sweden)

    XIAO Yugang

    2016-01-01

    Full Text Available The deformation monitoring algorithm with millimeter level precision based on BeiDou Navigation Satellite System (BDS was researched. The TurboEdit method was improved to detect small cycle slips, e.g. 1 cycle. Focusing on BDS constellation, a more efficient algorithm used to construct double-differenced observations was developed. The Bootstrap+Decision function method was utilized to improve the probability of biases fixing. Based on the improved algorithm above, a deformation monitoring software based on BDS was achieved. Afterwards, the availability of BDS in the field of deformation monitoring was analyzed in terms of satellites distribution and precision and accuracy of solutions, utilizing the observations acquired from the experimental platform. The conclusion was drawn that currently BDS is similar to GPS in terms of satellites distribution in the test area. The precision of short baselines derived from BDS is better than 1 mm for the horizontal components, better than 2 mm for the vertical components, which is still a little lower than GPS.

  15. Studies on a New Random Packing-Plum Flower Mini Ring%新一代的乱堆填料——梅花扁环

    Institute of Scientific and Technical Information of China (English)

    费维扬; 孙兰义; 郭庆丰

    2002-01-01

    The hydrodynamics and mass transfer of Plum Flower Mini Ring (PFMR), Pall Ring and Intalox Saddle were studied in a 600 mm diameter column with air-oxygen-water system over a wide range of liquid loads. It was shown fiom the experiments that PFMR had much lower resistance, larger throughput and higher mass transfer efficiency than Pall Ring and Intalox Saddle. It was clear from the comparison that existing equations could not predict the performance of packings very well at high liquid loads. Therefore, new semi-empirical equations of pressure drop, flooding gas velocity and height of transfer unit (HTU) were proposed based on the experimental data.

  16. Approaching zero: temporal effects of a restrictive antibiotic policy on hospital-acquired Clostridium difficile, extended-spectrum β-lactamase-producing coliforms and meticillin-resistant Staphylococcus aureus.

    Science.gov (United States)

    Dancer, S J; Kirkpatrick, P; Corcoran, D S; Christison, F; Farmer, D; Robertson, C

    2013-02-01

    A restrictive antibiotic policy banning routine use of ceftriaxone and ciprofloxacin was implemented in a 450-bed district general hospital following an educational campaign. Monthly consumption of nine antibiotics was monitored in defined daily doses (DDDs) per 1000 patient-occupied bed-days (1000 pt-bds) 9 months before until 16 months after policy introduction. Hospital-acquired Clostridium difficile, meticillin-resistant Staphylococcus aureus (MRSA) and extended-spectrum β-lactamase (ESBL)-producing coliform cases per month/1000 pt-bds were identified and reviewed throughout the hospital. Between the first and final 6 months of the study, average monthly consumption of ceftriaxone reduced by 95% (from 46.213 to 2.129 DDDs/1000 pt-bds) and that for ciprofloxacin by 72.5% (109.804 to 30.205 DDDs/1000 pt-bds). Over the same periods, hospital-acquisition rates for C. difficile reduced by 77% (2.398 to 0.549 cases/1000 pt-bds), for MRSA by 25% (1.187 to 0.894 cases/1000 pt-bds) and for ESBL-producing coliforms by 17% (1.480 to 1.224 cases/1000 pt-bds). Time-lag modelling confirmed significant associations between ceftriaxone and C. difficile cases at 1 month (correlation 0.83; P<0.005), and between ciprofloxacin and ESBL-producing coliform cases at 2 months (correlation 0.649; P=0.002). An audit performed 3 years after the policy showed sustained reduction in C. difficile rates (0.259 cases/1000 pt-bds), with additional decreases for MRSA (0.409 cases/1000 pt-bds) and ESBL-producing coliforms (0.809 cases/1000 pt-bds). In conclusion, banning two antibiotics resulted in an immediate and profound reduction in hospital-acquired C. difficile, with possible longer-term effects on MRSA and ESBL-producing coliform rates. Antibiotic stewardship is fundamental in the control of major hospital pathogens. PMID:23276500

  17. The disease-modifying effects of a Sativex-like combination of phytocannabinoids in mice with experimental autoimmune encephalomyelitis are preferentially due to Δ9-tetrahydrocannabinol acting through CB1 receptors.

    Science.gov (United States)

    Moreno-Martet, Miguel; Feliú, Ana; Espejo-Porras, Francisco; Mecha, Miriam; Carrillo-Salinas, Francisco J; Fernández-Ruiz, Javier; Guaza, Carmen; de Lago, Eva

    2015-11-01

    Sativex(®), an equimolecular combination of Δ(9)-tetrahydrocannabinol-botanical drug substance (Δ(9)-THC-BDS) and cannabidiol-botanical drug substance (CBD-BDS), is a licensed medicine that may be prescribed for alleviating specific symptoms of multiple sclerosis (MS) such as spasticity and pain. However, further evidence suggest that it could be also active as disease-modifying therapy given the immunomodulatory, anti-inflammatory and cytoprotective properties of their two major components. In this study, we investigated this potential in the experimental autoimmune encephalitis (EAE) model of MS in mice. We compared the effect of a Sativex-like combination of Δ(9)-THC-BDS (10 mg/kg) and CBD-BDS (10 mg/kg) with Δ(9)-THC-BDS (20 mg/kg) or CBD-BDS (20 mg/kg) administered separately by intraperitoneal administration to EAE mice. Treatments were initiated at the time that symptoms appear and continued up to the first relapse of the disease. The results show that the treatment with a Sativex-like combination significantly improved the neurological deficits typical of EAE mice, in parallel with a reduction in the number and extent of cell aggregates present in the spinal cord which derived from cell infiltration to the CNS. These effects were completely reproduced by the treatment with Δ(9)-THC-BDS alone, but not by CBD-BDS alone which only delayed the onset of the disease without improving disease progression and reducing the cell infiltrates in the spinal cord. Next, we investigated the potential targets involved in the effects of Δ(9)-THC-BDS by selectively blocking CB(1) or PPAR-γ receptors, and we found a complete reversion of neurological benefits and the reduction in cell aggregates only with rimonabant, a selective CB(1) receptor antagonist. Collectively, our data support the therapeutic potential of Sativex as a phytocannabinoid formulation capable of attenuating EAE progression, and that the active compound was Δ(9)-THC-BDS acting through CB(1

  18. Monoterpene Glycosides from the Roots of Paeonia lactiflora

    Institute of Scientific and Technical Information of China (English)

    Xiao Ling WANG; Wei JIAO; Xun LIAO; Shu Ling PENG; Li Sheng DING

    2006-01-01

    A new monoterpene glycoside, together with nine known ones, 3-O-methylpaeoniflorin,mudanpioside J, paeoniflorin, benzoylpaeoniflorin, oxypaeoniflorin, benzoyloxypaeoniflorin,oxybenzoylpaeoniflorin, albiflorin and lactiflorin, was isolated from the roots of Paeonia lactiflora Pall.. The structure of the new compound was elucidated as galloylalbiflorin by the spectroscopic evidence including ESI-MS, 1D- and 2D-NMR spectra.

  19. Väikeste ridamajade rida Kloostrimetsas = A Row of Little Row Houses in Kloostrimetsa / Urmas Oja

    Index Scriptorium Estoniae

    Oja, Urmas, 1981-2012

    2003-01-01

    Neljast ridaelamust, millest kaks on propjekteerinud Ado Eigi (Ado Eigi Arhitektuuribüroo, konstruktsioonid: Uno Pall, projekt 2002, valminud 2003), ühe Ott Kadarik ja Mihkel Tüür (COO Arhitektid, projekt 2002, valminud 2003) ning ühe arhitektuuribüroo Kosmos (valminud 2004). Sisevaade, 6 välisvaadet, 5 korruste plaani

  20. Use of “Homeopathic” Ligand-Free Palladium as Catalyst for Aryl-Aryl Coupling Reactions

    NARCIS (Netherlands)

    Alimardanov, Asaf; Schmieder-van de Vondervoort, Lizette; Vries, André H.M. de; Vries, Johannes G. de

    2004-01-01

    We have previously shown that the use of ligand-free palladium employing Pd(OAc)2 as catalyst precursor in the Heck reaction of aryl bromides is possible if low catalyst loadings, typically between 0.01 – 0.1 mol % are used. We have now tested this phenomenon, which we have dubbed “homeopathic” pall

  1. Mõtlejate mõjud ja sotsiaalne aktsionism Tallinna galeriides / Margaret Tali

    Index Scriptorium Estoniae

    Tali, Margaret

    2002-01-01

    Marko Laimre näitus "Must pall" Tallinna Kunstihoones, Liina Siibi näitus "Klips" (plakatid, videod) Hansapanga galeriis, Stuudio 22 näitus "déja vu" (graafika) Pärnu mnt. 27 galeriis, Eesti Kunstiakadeemia üliõpilaste joonistused "Tühjus ja Ruum" G-galeriis

  2. Education, Learning and Development in the Periphery

    DEFF Research Database (Denmark)

    Rasmussen, Palle

    2012-01-01

    Palle Rasmussens artikkel handler om utdannelse, læring og utvikling i utkantområder, belyst gjennom utdanningens rolle i den regionale utviklingen i Danmark. Rasmussen peker på at Danmark har et velutviklet utdanningssystem som sikrer en relativt lik fordeling av befolkningens utdanningsmulighet...

  3. Eestlaste pension kinnisvaraturu meelevallas / Anne Oja

    Index Scriptorium Estoniae

    Oja, Anne, 1970-

    2007-01-01

    Ilmunud ka: Delovõje Vedomosti 22. aug. lk. 6. Eesti pensionifondid on kinnisvarasse paigutanud umbes miljard krooni. Kinnisvarafirmade võlakirjade hind võib kujuneda madalaks. Pankade kommentaarid. Vt. samas: Tulevased pensionärid magavad rahulikult. Tabel: Pensionifondide investeeringud kinnisvarasse. Kommenteerivad: Ingmar Mattus, Kalle Palling, Karoli Hindriks, Pertti Rahnel, Andre Nõmm, Urmas Laur, Kristjan Lepik. Kommentaarid ainult eestikeelse art. juures

  4. Hydrodynamic behaviour of a gas—solid counter-current packed column at trickle flow

    NARCIS (Netherlands)

    Roes, A.W.M.; Swaaij, van W.P.M.

    1979-01-01

    Trickle flow of a more or less fluidized catalyst through a packed column is a promising new gas—solid counter-current operation. The hydrodynamic, behaviour of such a column, filled with dumped PALL rings, has been investigated, while some results have been obtained with RASCHIG rings and cylindric

  5. Eesti Energia nõukogu liikmed Jaotusvõrgu hinnatõusutaotlust kommenteerima ei kipu / Katre Pilvinski

    Index Scriptorium Estoniae

    Pilvinski, Katre

    2010-01-01

    Eesti Energia nõukogu liige Kalle Palling kommenteerib peaminister Andrus Ansipi öeldut, et Eesti Energia investeeringud tuleb üle vaadata. Nõukogu liikme Rein Kilgi sõnul tunduvad talle rünnakud Eesti Energia vastu ülekohtused

  6. Morphological and molecular characterization of Globodera populations from Oregon and Idaho

    Science.gov (United States)

    A new species of Globodera, identified from three potato fields, is described herein as Globodera pseudopallida n. sp. Morphologically, G. pseudopallida n. sp. exhibits some unique features that are not consistent between populations; but molecularly, G. pseudopallida n. sp. is distinct from G. pall...

  7. Obama and Cameron’s Ping-pong Diplomacy Show

    Institute of Scientific and Technical Information of China (English)

    李新

    2011-01-01

    They seemed like best mates. Every time one of them got a point,they did a high fiv(e击掌相庆). The men were the British Prime Minister,David Cameron, and the President of the USA, Barack Obama.The palling around(结伴玩耍)took place during Mr. Obama’s state

  8. Global exchange and accumulation of non-native plants

    NARCIS (Netherlands)

    Kleunen, Van Mark; Dawson, Wayne; Essl, Franz; Pergl, Jan; Winter, Marten; Weber, Ewald; Kreft, Holger; Weigelt, Patrick; Kartesz, John; Nishino, Misako; Antonova, Liubov A.; Barcelona, Julie F.; Cabezas, Francisco J.; Cárdenas, Dairon; Cárdenas-Toro, Juliana; Castaño, Nicolás; Chacón, Eduardo; Chatelain, Cyrille; Ebel, Aleksandr L.; Figueiredo, Estrela; Fuentes, Nicol; Groom, Quentin J.; Henderson, Lesley; Inderjit,; Kupriyanov, Andrey; Masciadri, Silvana; Meerman, Jan; Morozova, Olga; Moser, Dietmar; Nickrent, Daniel L.; Patzelt, Annette; Pelser, Pieter B.; Baptiste, María P.; Poopath, Manop; Schulze, Maria; Seebens, Hanno; Shu, Wen Sheng; Thomas, Jacob; Velayos, Mauricio; Wieringa, Jan J.; Pyšek, Petr

    2015-01-01

    <p>All around the globe, humans have greatly altered the abiotic and biotic environment with ever-increasing speed. One defining feature of the Anthropocene epoch is the erosion of biogeographical barriers by human-mediated dispersal of species into new regions, where they can naturalize and cause e

  9. Reviving ethics in sports time for physicians to act.

    Science.gov (United States)

    Pipe, A

    1998-06-01

    When will we face the fact that we're producing some really ugly, violent young men?" observed my friend, an internationally prominent basketball coach, who is given neither to hand-wringing nor to strident overstatement. His disquieting words cast a pall over an already disheartening conversation about the state of contemporary sports. PMID:20086820

  10. Study on Clematisnzans Hurica Rupr's Identification and Statographic Fingerprint Atlas%东北铁线莲的鉴别与色谱指纹图谱的研究

    Institute of Scientific and Technical Information of China (English)

    曹婷婷; 杨帆; 邢晶晶

    2011-01-01

    @@ 毛茛科铁线莲属植物约有300种.我国有108种.其中作为正品威灵仙人药的为威灵仙 Clematis chinesis Osbeck,棉团铁线莲 Clematishexapetala Pall 和东北铁线莲 Clematisnzans hurica Rupr的干燥根及根茎.

  11. Conference on Policies on Pesticide Use by Local and Regional Authorities 25th April 2006 Wageningen UR, Wageningen, The Netherlands

    NARCIS (Netherlands)

    Graugaard, S.; Jensen, K.; Melander, B.; Kempenaar, C.

    2006-01-01

    Table of Contents: 1. Inventory of policies on pesticide use by local and regional authorities in the 7 project countries (DE, DK, FI, LV, NL, SE, UK) [Palle Kristoffersen & Anne Merete Rask (DK)]; 2. Dutch policy regarding pesticide use on hard surfaces [Wilbert van Zeventer (NL)]; 3. Handling

  12. "Vaesus on disainerile parim aeg" / Masayo Ave

    Index Scriptorium Estoniae

    Ave, Masayo

    2007-01-01

    Masayo Ave oma elust Euroopas, probleemidest ja kohalike väärtuste arendamisest disainis ja sellest, et puudus paneb aju tööle. Illustratsioonidel valik tema toodetest - öövalgusti Fish Eye, täispuhutav pall-iste, laua- ja seinalamp Genesi, päevapadi Toft jt.

  13. TWAS Participating in Social Advancement --An Interview with Prof. Jacob Palis

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    "We should have the promotion of research and development in the industry, and for that scientists should be hired ... Science not only should be promoted by its intellectual challenges of understanding nature, but also should be towards applications in benefit of Society, without reservations that science would be less noble because of that." Prof. Jacob Palls.

  14. Kontseptuaalne ja liikumispõhine nüüdistants Täiskuu tantsufestivalil Soomes / Evelin Lagle

    Index Scriptorium Estoniae

    Lagle, Evelin, 1986-

    2010-01-01

    Tantsufestivalist "Täudenkuun Tanssit" (Full Moon Dance Festival). Tantsulavastustest - Tommi Kitti "Riff", Jyrki Karttuneni "Situation Room", Kenneth Kvanströmi "Destruction Song", Liisa Petti "Mabel or the Gueen of Bones", Elina Pirineni "A Friend of the Pianist", Johanna Tuukkaneni "Outstanding Performance" ja Palle Granhoj sooloetendus "(...It's a Very Big Secret...)"

  15. Epidemiology of Birth Defects Based on a Birth Defect Surveillance System from 2005 to 2014 in Hunan Province, China.

    Directory of Open Access Journals (Sweden)

    Donghua Xie

    Full Text Available To describe the epidemiology of birth defects (BDs in perinatal infants in Hunan Province, China, between 2005 and 2014.The BD surveillance data of perinatal infants (for stillbirth, dead fetus or live birth between 28 weeks of gestation and 7 days after birth were collected from 52 registered hospitals of Hunan between 2005 and 2014. The prevalence rates of BDs with 95% confidence interval (CI and crude odds ratio (ORs were calculated to examine the associations of infant gender, maternal age, and region (urban vs rural with BDs.From 2005 to 2014, there were a total of 925413 perinatal infants of which 17753 had BDs, with the average prevalence of 191.84 per 10000 PIs (perinatal infants, showing a significant uptrend. The risks of BDs are higher in urban areas versus rural areas (OR = 1.20, in male infants versus female infants (OR = 1.19, and in mothers above age 35 versus those below age 35 (OR = 1.24. The main five types of BDs are Congenital heart defects (CHD, Other malformation of external ear (OMEE, Polydactyly, Congenital malformation of kidney (CMK, and Congenital talipes equinovarus (CTE. From 2005 to 2014, the prevalence rates (per 10000 PIs of CHD and CMK increased significantly from 22.56 to 74 (OR = 3.29, 95%CI: 2.65-4.11 and from 7.61 to 14.62 (OR = 1.92, 95%CI:1.30-2.84, respectively; the prevalence rates of congenital hydrocephalus and neural tube defects (NTDs decreased significantly from 11.8 to 5.29 (OR = 0.45, 95%CI: 0.31-0.65 and from 7.87 to 1.74 (OR = 0.22, 95%CI: 0.13-0.38, respectively.The prevalence rates of specific BDs in perinatal infants in Hunan have changed in the last decade. Urban pregnant women, male perinatal infants, and mothers above age 35 present different prevalence rates of BDs. Wider use of new diagnosis technology, improving the ability of monitoring, strengthening the publicity and education are important to reduce the prevalence of BDs.

  16. A CURRICULAR PARADIGM BASED UPON VEDIC EPISTEMOLOGY: AN APPROACH TO DEVELOPING THE WHOLE PERSON

    Directory of Open Access Journals (Sweden)

    Dr. Kumar LAXMAN

    2012-10-01

    Full Text Available The Bhaktivedanta Dharma School (BDS provides quality but yet affordable holistic education to the local Indonesian community in Bali. The school’s educational orientation is inspired by the Vedic (Hindu goals of fruition of knowledge (Vedanta or the essence of the Vedic scriptures and devotion (Bhakti to God (Krishna. The curriculum integrates the best of both the eastern and western approaches to enriching young minds. The strengths of both value systems are seen to be crucial in the all-round, dynamic development of children. Not only is academic excellence emphasized but character development and awareness of the higher spiritual purpose of life are also imparted to the kids. The role of the teacher extends beyond the taught curriculum and s/he plays a vital role in the character development of the child, through his or her own personal example. This paper examines the pedagogical effectiveness of the implemented framework of holistic education at BDS based upon the perceptions and experiences of the teachers working in the school. An ethnographic approach was employed as the main research methodology with participant observation and open-ended interviewing the primary means of data collection and analysis. A total of six teachers working at BDS were interviewed in this study. The findings of the study provide deeper insights on the differences between BDS and mainstream, traditional schools in terms of their structural and curricular characteristics and the key challenges participant teachers faced in orientating to the alternative learning culture of BDS.

  17. Analysis of BeiDou Satellite Measurements with Code Multipath and Geometry-Free Ionosphere-Free Combinations.

    Science.gov (United States)

    Zhao, Qile; Wang, Guangxing; Liu, Zhizhao; Hu, Zhigang; Dai, Zhiqiang; Liu, Jingnan

    2016-01-20

    Using GNSS observable from some stations in the Asia-Pacific area, the carrier-to-noise ratio (CNR) and multipath combinations of BeiDou Navigation Satellite System (BDS), as well as their variations with time and/or elevation were investigated and compared with those of GPS and Galileo. Provided the same elevation, the CNR of B1 observables is the lowest among the three BDS frequencies, while B3 is the highest. The code multipath combinations of BDS inclined geosynchronous orbit (IGSO) and medium Earth orbit (MEO) satellites are remarkably correlated with elevation, and the systematic "V" shape trends could be eliminated through between-station-differencing or modeling correction. Daily periodicity was found in the geometry-free ionosphere-free (GFIF) combinations of both BDS geostationary Earth orbit (GEO) and IGSO satellites. The variation range of carrier phase GFIF combinations of GEO satellites is -2.0 to 2.0 cm. The periodicity of carrier phase GFIF combination could be significantly mitigated through between-station differencing. Carrier phase GFIF combinations of BDS GEO and IGSO satellites might also contain delays related to satellites. Cross-correlation suggests that the GFIF combinations' time series of some GEO satellites might vary according to their relative geometries with the sun.

  18. BANYAN. VII. A New Population of Young Substellar Candidate Members of Nearby Moving Groups from the BASS Survey

    CERN Document Server

    Gagné, Jonathan; Cruz, Kelle L; Lafrenière, David; Doyon, René; Malo, Lison; Burgasser, Adam J; Naud, Marie-Eve; Artigau, Étienne; Bouchard, Sandie; Gizis, John E; Albert, Loïc

    2015-01-01

    [Abbreviated] We present the results of a near-infrared (NIR) spectroscopic follow-up survey of 182 M4-L7 low-mass stars and brown dwarfs (BDs) from the BANYAN All-Sky Survey (BASS) for candidate members of nearby, young moving groups (YMGs). We confirm signs of low-gravity for 42 new BD discoveries with estimated masses between 8-75 $M_{Jup}$ and identify previously unrecognized signs of low gravity for 24 known BDs. This allows us to refine the fraction of low-gravity dwarfs in the high-probability BASS sample to $\\sim$82%. We use this unique sample of 66 young BDs, supplemented with 22 young BDs from the literature, to construct new empirical NIR absolute magnitude and color sequences for low-gravity BDs. We obtain a spectroscopic confirmation of low-gravity for 2MASS J14252798-3650229, which is a new $\\sim$27 $M_{Jup}$, L4 $\\gamma$ bona fide member of AB Doradus. We identify a total of 19 new low-gravity candidate members of YMGs with estimated masses below 13 $M_{Jup}$, seven of which have kinematically ...

  19. Detection of brown dwarf-like objects in the core of NGC3603

    CERN Document Server

    Spezzi, Loredana; De Marchi, Guido; Young, Erick T; Paresce, Francesco; Dopita, Michael A; Andersen, Morten; Panagia, Nino; Balick, Bruce; Bond, Howard E; Calzetti, Daniela; Carollo, C Marcella; Disney, Michael J; Frogel, Jay A; Hall, Donald N B; Holtzman, Jon A; Kimble, Randy A; McCarthy, Patrick J; O'Connell, Robert W; Saha, Abhijit; Silk, Joseph I; Trauger, John T; Walker, Alistair R; Whitmore, Bradley C; Windhorst, Rogier A

    2011-01-01

    We use near-infrared data obtained with the Wide Field Camera 3 (WFC3) on the Hubble Space Telescope to identify objects having the colors of brown dwarfs (BDs) in the field of the massive galactic cluster NGC 3603. These are identified through use of a combination of narrow and medium band filters spanning the J and H bands, and which are particularly sensitive to the presence of the 1.3-1.5{\\mu}m H2O molecular band - unique to BDs. We provide a calibration of the relationship between effective temperature and color for both field stars and for BDs. This photometric method provides effective temperatures for BDs to an accuracy of {\\pm}350K relative to spectroscopic techniques. This accuracy is shown to be not significantly affected by either stellar surface gravity or uncertainties in the interstellar extinction. We identify nine objects having effective temperature between 1700 and 2200 K, typical of BDs, observed J-band magnitudes in the range 19.5-21.5, and that are strongly clustered towards the luminous...

  20. Analysis of BeiDou Satellite Measurements with Code Multipath and Geometry-Free Ionosphere-Free Combinations

    Directory of Open Access Journals (Sweden)

    Qile Zhao

    2016-01-01

    Full Text Available Using GNSS observable from some stations in the Asia-Pacific area, the carrier-to-noise ratio (CNR and multipath combinations of BeiDou Navigation Satellite System (BDS, as well as their variations with time and/or elevation were investigated and compared with those of GPS and Galileo. Provided the same elevation, the CNR of B1 observables is the lowest among the three BDS frequencies, while B3 is the highest. The code multipath combinations of BDS inclined geosynchronous orbit (IGSO and medium Earth orbit (MEO satellites are remarkably correlated with elevation, and the systematic “V” shape trends could be eliminated through between-station-differencing or modeling correction. Daily periodicity was found in the geometry-free ionosphere-free (GFIF combinations of both BDS geostationary Earth orbit (GEO and IGSO satellites. The variation range of carrier phase GFIF combinations of GEO satellites is −2.0 to 2.0 cm. The periodicity of carrier phase GFIF combination could be significantly mitigated through between-station differencing. Carrier phase GFIF combinations of BDS GEO and IGSO satellites might also contain delays related to satellites. Cross-correlation suggests that the GFIF combinations’ time series of some GEO satellites might vary according to their relative geometries with the sun.

  1. Dielectric response and novel electromagnetic modes in three-dimensional Dirac semimetal films

    Science.gov (United States)

    Kotov, O. V.; Lozovik, Yu. E.

    2016-06-01

    Using the Kubo formalism we have calculated the local dynamic conductivity of a bulk, i.e., three-dimensional (3D), Dirac semimetal (BDS). We obtain that at frequencies lower than Fermi energy the metallic response in a BDS film manifests in the existence of surface-plasmon polaritons, but at higher frequencies the dielectric response is dominated and it occurs that a BDS film behaves as a dielectric waveguide. At this dielectric regime we predict the existence inside a BDS film of novel electromagnetic modes, a 3D analog of the transverse electric waves in graphene. We also find that the dielectric response manifests as the wide-angle passband in the mid-infrared (IR) transmission spectrum of light incident on a BDS film, which can be used for the interferenceless omnidirectional mid-IR filtering. The tuning of the Fermi level of the system allows us to switch between the metallic and the dielectric regimes and to change the frequency range of the predicted modes. This makes BDSs promising materials for photonics and plasmonics.

  2. Analysis of BeiDou Satellite Measurements with Code Multipath and Geometry-Free Ionosphere-Free Combinations

    Science.gov (United States)

    Zhao, Qile; Wang, Guangxing; Liu, Zhizhao; Hu, Zhigang; Dai, Zhiqiang; Liu, Jingnan

    2016-01-01

    Using GNSS observable from some stations in the Asia-Pacific area, the carrier-to-noise ratio (CNR) and multipath combinations of BeiDou Navigation Satellite System (BDS), as well as their variations with time and/or elevation were investigated and compared with those of GPS and Galileo. Provided the same elevation, the CNR of B1 observables is the lowest among the three BDS frequencies, while B3 is the highest. The code multipath combinations of BDS inclined geosynchronous orbit (IGSO) and medium Earth orbit (MEO) satellites are remarkably correlated with elevation, and the systematic “V” shape trends could be eliminated through between-station-differencing or modeling correction. Daily periodicity was found in the geometry-free ionosphere-free (GFIF) combinations of both BDS geostationary Earth orbit (GEO) and IGSO satellites. The variation range of carrier phase GFIF combinations of GEO satellites is −2.0 to 2.0 cm. The periodicity of carrier phase GFIF combination could be significantly mitigated through between-station differencing. Carrier phase GFIF combinations of BDS GEO and IGSO satellites might also contain delays related to satellites. Cross-correlation suggests that the GFIF combinations’ time series of some GEO satellites might vary according to their relative geometries with the sun. PMID:26805831

  3. Analysis of BeiDou Satellite Measurements with Code Multipath and Geometry-Free Ionosphere-Free Combinations.

    Science.gov (United States)

    Zhao, Qile; Wang, Guangxing; Liu, Zhizhao; Hu, Zhigang; Dai, Zhiqiang; Liu, Jingnan

    2016-01-01

    Using GNSS observable from some stations in the Asia-Pacific area, the carrier-to-noise ratio (CNR) and multipath combinations of BeiDou Navigation Satellite System (BDS), as well as their variations with time and/or elevation were investigated and compared with those of GPS and Galileo. Provided the same elevation, the CNR of B1 observables is the lowest among the three BDS frequencies, while B3 is the highest. The code multipath combinations of BDS inclined geosynchronous orbit (IGSO) and medium Earth orbit (MEO) satellites are remarkably correlated with elevation, and the systematic "V" shape trends could be eliminated through between-station-differencing or modeling correction. Daily periodicity was found in the geometry-free ionosphere-free (GFIF) combinations of both BDS geostationary Earth orbit (GEO) and IGSO satellites. The variation range of carrier phase GFIF combinations of GEO satellites is -2.0 to 2.0 cm. The periodicity of carrier phase GFIF combination could be significantly mitigated through between-station differencing. Carrier phase GFIF combinations of BDS GEO and IGSO satellites might also contain delays related to satellites. Cross-correlation suggests that the GFIF combinations' time series of some GEO satellites might vary according to their relative geometries with the sun. PMID:26805831

  4. Enhancement of dibenzothiophene biodesulfurization using {beta}-cyclodextrins in oil-to-water media

    Energy Technology Data Exchange (ETDEWEB)

    Ainhoa Caro; Pedro Leton; Eloy Garcia-Calvo; Leonardo Setti [Universidad de Alcala, Madrid (Spain). Departamento de Quimica Analitica e Ingeniera Quimica

    2007-11-15

    It has been reported that biodesulfurization (BDS) of dibenzothiophene (DBT) in oil-to-water emulsions is carried out by growing cells of the aerobic Rhodococcus erythropolis IGTS8 strain and developing the so-called 4S desulfurization pathway. On adding {beta}-cyclodextrins, it is possible to improve the BDS yields, increase the diffusion of DBT into the aqueous phase or avoid the HBP accumulation. Moreover, by using greater biocatalyst initial concentrations and adding 15 ppm of {beta}-cyclodextrin, a very high BDS yield has been observed, but the presence of mass transfer limitations and the inhibition effects were not satisfactorily avoided. The Haldane kinetic model agreed well with the experimental results obtained, and the values of the kinetic parameters were determined. Short communication. 20 refs., 2 figs., 2 tabs.

  5. Dynamics at the Polymer/Nanoparticle Interface in Poly(2-vinylpyridine)/Silica Nanocomposites.

    Energy Technology Data Exchange (ETDEWEB)

    Holt, Adam P [ORNL; Griffin, Phillip [University of Tennessee (UTK) and Oak Ridge National Laboratory (ORNL); Bocharova, Vera [ORNL; Agapov, Alexander L [ORNL; Imel, Adam E [ORNL; Dadmun, Mark D [ORNL; Sangoro, Joshua R [ORNL; Sokolov, Alexei P [ORNL

    2014-01-01

    The static and dynamic properties of poly(2-vinylpyridine)/silica nanocomposites are investigated by temperature modulated differential scanning calorimetry, broadband dielectric spectroscopy (BDS), small-angle X-ray scattering (SAXS), and transmission electron microscopy. Both BDS and SAXS detect the existence of an interfacial polymer layer on the surface of nanoparticles. The results show that whereas the calorimetric glass transition temperature varies only weakly with nanoparticle loading, the segmental mobility of the polymer interfacial layer is slower than the bulk polymer by 2 orders of magnitude. Detailed analysis of BDS and SAXS data reveal that the interfacial layer has a thickness of 4 6 nm irrespective of the nanoparticle concentration. These results demonstrate that in contrast to some recent articles on polymer nanocomposites, the interfacial polymer layer is by no means a dead layer . However, its existence might provide some explanation for controversies surrounding the dynamics of polymer nanocomposites.

  6. Improved Measurement of Absolute Hadronic Branching Fractions of the Ds+ Meson

    CERN Document Server

    Onyisi, P U E; Cinabro, D; Smith, M J; Zhou, P; Naik, P; Rademacker, J; Edwards, K W; Briere, R A; Vogel, H; Rosner, J L; Alexander, J P; Cassel, D G; Das, S; Ehrlich, R; Gibbons, L; Gray, S W; Hartill, D L; Heltsley, B K; Kreinick, D L; Kuznetsov, V E; Patterson, J R; Peterson, D; Riley, D; Ryd, A; Sadoff, A J; Shi, X; Sun, W M; Yelton, J; Rubin, P; Lowrey, N; Mehrabyan, S; Selen, M; Wiss, J; Libby, J; Kornicer, M; Mitchell, R E; Besson, D; Pedlar, T K; Cronin-Hennessy, D; Hietala, J; Dobbs, S; Metreveli, Z; Seth, K K; Tomaradze, A; Xiao, T; Powell, A; Thomas, C; Wilkinson, G; Asner, D M; Tatishvili, G; Ge, J Y; Miller, D H; Shipsey, I P J; Xin, B; Adams, G S; Napolitano, J; Ecklund, K M; Insler, J; Muramatsu, H; Pearson, L J; Thorndike, E H; Artuso, M; Blusk, S; Mountain, R; Skwarnicki, T; Stone, S; Wang, J C; Zhang, L M

    2013-01-01

    The branching fractions of Ds meson decays serve to normalize many measurements of processes involving charm quarks. Using 586 pb^-1 of e+ e- collisions recorded at a center of mass energy of 4.17 GeV, we determine absolute branching fractions for 13 Ds decays in 16 reconstructed final states with a double tag technique. In particular we make a precise measurement of the branching fraction B(Ds -> K- K+ pi+) = (5.55 +- 0.14 +- 0.13)%, where the uncertainties are statistical and systematic respectively. We find a significantly reduced value of B(Ds -> pi+ pi0 eta') compared to the world average, and our results bring the inclusively and exclusively measured values of B(Ds -> eta' X)$ into agreement. We also search for CP-violating asymmetries in Ds decays and measure the cross-section of e+ e- -> Ds* Ds at Ecm = 4.17 GeV.

  7. Folic acid and primary prevention of birth defects.

    Science.gov (United States)

    Taruscio, Domenica; Carbone, Pietro; Granata, Orietta; Baldi, Francesca; Mantovani, Alberto

    2011-01-01

    Birth defects (BDs) are an important public health problem, due to their overall incidence, occurring in 2-3% of live births in European Union. Neural tube defects (NTDs) are among major NTDs, due to their severity and relatively high incidence; in the meanwhile NTDs are also the most effectively preventable BDs to date. In particular, an adequate folic acid (FA) intake reduces both the occurrence and the recurrence of NTDs; FA is the synthetic form of folates, naturally occurring vitamins in a number of foods, especially vegetables. The daily intake of 0.4 mg of FA should be recommended to all women of childbearing age who plan to become pregnant. The Italian Network for Primary Prevention of BDs through FA Promotion has achieved a significant improvement in FA awareness and use in the periconceptional period. Nevertheless, primary prevention of BDs needs to make further progress; the Italian National Centre for Rare Diseases participates in european sureveillance of congenital anomalies (EUROCAT) Joint Action as coordinator of activities on the effectiveness of BDs prevention. Mandatory food fortification with FA has not been introduced in any European country. The health benefits of FA in reducing the risk of NTDs are undisputed; however mechanistic and animal studies suggest a relationship between high FA intakes and increased cancer promotion, while human studies are still inconsistent and inconclusive. A Working Group organized by the European Food Safety Authority pointed out significant uncertainties about fortification safety and the need for more studies; currently, FA intake from fortified foods and supplements should not exceed 1 mg/day in adults. In conclusion, based on up-to-date scientific evidence, the Italian Network strategy pivots on periconceptional supplementation integrated with promotion of healthy eating habits, support to health education, enhancing the role of women in managing life choices about their health and pregnancy and increasing

  8. The Superconducting Magnets of the ILC Beam Delivery System

    Energy Technology Data Exchange (ETDEWEB)

    Parker, B.; Anerella, M.; Escallier, J.; He, P.; Jain, A.; Marone, A.; /Brookhaven; Nosochkov, Y.; Seryi, Andrei; /SLAC

    2007-09-28

    The ILC Beam Delivery System (BDS) uses a variety of superconducting magnets to maximize luminosity and minimize background. Compact final focus quadrupoles with multifunction correction coils focus incoming beams to few nanometer spot sizes while focusing outgoing disrupted beams into a separate extraction beam line. Anti-solenoids mitigate effects from overlapping focusing and the detector solenoid field. Far from the interaction point (IP) strong octupoles help minimize IP backgrounds. A low-field but very large aperture dipole is integrated with the detector solenoid to reduce backgrounds from beamstrahlung pairs generated at the IP. Physics requirements and magnetic design solutions for the BDS superconducting magnets are reviewed in this paper.

  9. China Satellite Navigation Conference

    CERN Document Server

    Liu, Jingnan; Fan, Shiwei; Wang, Feixue

    2016-01-01

    These Proceedings present selected research papers from CSNC2016, held during 18th-20th May in Changsha, China. The theme of CSNC2016 is Smart Sensing, Smart Perception. These papers discuss the technologies and applications of the Global Navigation Satellite System (GNSS), and the latest progress made in the China BeiDou System (BDS) especially. They are divided into 12 topics to match the corresponding sessions in CSNC2016, which broadly covered key topics in GNSS. Readers can learn about the BDS and keep abreast of the latest advances in GNSS techniques and applications.

  10. Physical volcanology, geochemistry and basin evolution of the Ediacaran volcano-sedimentary succession in the Bas Draâ inlier (Ouarzazate Supergroup, Western Anti-Atlas, Morocco)

    Science.gov (United States)

    Karaoui, Brahim; Breitkreuz, Christoph; Mahmoudi, Abdelkader; Youbi, Nasrrddine

    2014-11-01

    New geologic mapping, lithofacies and granulometric analysis, and geochemistry from the volcano-sedimentary successions of the central part of the Bas Draâ inlier, Western Anti-Atlas, constrain the Ediacaran Ouarzazate Supergroup evolution during the post-collisional stage of the Pan-African orogeny. Volcanosedimentary facies analysis is the key aspect of the present contribution. We distinguished sixteen terrestrial volcanosedimentary lithofacies in the Bas Draâ succession (BDS), which reaches a total thickness of 2000 m. BDS evolution can be grouped into four units (Aouinet Aït Oussa I to IV, AO I-AO IV). The earliest volcanic activity produced rhyolitic ignimbrite sheets (AO I), which had been considered as lava flows by previous workers, and which were presumably related to caldera system(s). During AO II, a complex of high-silica andesitic and rhyolitic lavas formed, punctuated by the explosive eruption of a high-temperature silica-rich magma leading to the formation of parataxitic ignimbrite. AO III consists of basalt and andesite lava fields and small explosive, in parts phreatomagmatic volcanic vents. It is dissected by fluvial systems depositing external non-volcanic and local volcanic debris. BDS evolution terminated with the formation of a large SiO2-rich lava dome complex (AO IV), accompanied by small basalt effusive event. Volcanosedimentary facies analysis infers that the BDS evolved in a continental extensional setting developing in a low topography under humid paleoclimatic conditions. Alteration textures are dominated by a piemontite-calcite-albite-quartz (+ iron oxides) assemblage. Chemical analysis of BDS volcanic and subvolcanic rocks belongs to high-k calc-alkaline and alkali-calcic to alkaline magmatic trend typical for a post-collision setting. Trace elements spidergrams show a pattern typical for subduction-related suites of orogenic belts. REE patterns show moderate enrichment in LREE relative to flat HREE, with strong negative Eu

  11. Mindfulness and bodily distress.

    Science.gov (United States)

    Fjorback, Lone Overby

    2012-11-01

    We have created a mindfulness approach to treat patients who experience multiple, persistent, and disabling physical symptoms that cannot be explained by a well-defined medical or surgical condition. Randomized controlled trials in this area are few, and research is hampered by the lack of clear definitions. Bodily distress syndrome (BDS) or bodily stress is an empirically defined definition unifying various conditions such as fibromyalgia, chronic fatigue syndrome, and somatization disorder. In the present PhD, we explored whether patients suffering from BDS may be committed to mental training in the form of mindfulness therapy, which is a mindfulness program specifically targeted patients suffering from BDS. The theoretical model for including mindfulness training in the treatment of BDS is based on identified neurobiological impairments in these patients and the neurobiological improvements that mindfulness training may offer. BDS is a major public health issue possibly associated with the pathology of the immuno-endocrine and autonomic nervous system. BDS patients are often stigmatized, and effective treatment is rarely delivered, which leaves these patients isolated, left by themselves, vulnerable to potentially harming medical and/or alternative treatments. Accordingly, there is a need for non-harming practical tools that patients can learn to master so that they can improve the ability to take responsibility for their own health and wellbeing. Mindfulness-Based Stress Reduction (MBSR) is a group program that employs mindfulness practice to alleviate suffering associated with physical, psychosomatic, and psychiatric disorders. Mindfulness-Based Cognitive Therapy (MBCT) is designed to prevent depressive relapse. Paper I and II present systematic literature reviews only of randomized controlled trials on MBSR and MBCT. The effect of MBSR has been explored on fibromyalgia in three studies, none of them showed convincing results, but gave some indications as to

  12. Two Na+ and Cl- Hyperaccumulators of the Chenopodiaceae

    Institute of Scientific and Technical Information of China (English)

    Ke-Fu ZHAO; Hai FAN; Jie SONG; Ming-Xia SUN; Bao-Zeng WANG; Sheng-Qiang ZHANG; I. A. UNGAR

    2005-01-01

    The authors found five sodium (Na+) and chloride (Cl-) hyperaccumulating halophytes in the Temperate Desert of Xinjiang, China and studied two of them (Suaeda salsa (L.) Pall. and Kalidium folium (Pall.) Moq.). K. folium and S. salsa had a NaCl content of 32.1% and 29.8%, respectively, on a dry weight basis. X-ray microanalysis of the Na+ in the vacuole, apoplasts and cytoplasm of the two plants indicated a ratio of 7.3:5.6:1.0 in K. folium and 7.3:6.6:1.0 in S. salsa. These data show that K. folium and S. salsa both have a high Na+ and Cl-accumulating capacity, which is related to high activity oftonoplast H+-ATPase and H+-PPase.

  13. Studies on a New Random Packing-Plum Flower Mini Ring

    Institute of Scientific and Technical Information of China (English)

    费维扬; 孙兰义; 等

    2002-01-01

    The hydrodynamics and mass transfer of Plum Flower Mini Ring(PFMR),Pall Ring and Intalox Saddle were studied in a 600mm diameter column with air-oxygen-water system over a wide range of liquid loasds.It was shown from the experiments that PFMR had much lower resistance,larger throughput and higher mass transfer efficiency than Pall Ring and Intalox Saddle.It was clear from the comparison that existing equations could not predict the performance of packings very well at high liquied loads.Therefore,new semi-empirical equations of pressure drop,flooding gas velocity and height of transfer unit(HTU)were proposed based on the experimental data.

  14. The use of skin surface electropotentials for breast cancer detection--preliminary clinical trial results obtained using the biofield diagnostic system.

    Science.gov (United States)

    Sree, Subbhuraam Vinitha; Ng, E Y K; Kaw, G; U, Rajendra Acharya; Chong, B K

    2011-02-01

    The purpose of this study is to evaluate the efficiency of the Biofield Diagnostic System (BDS) as an adjunct to established diagnostic techniques such as mammography and ultrasound in differentiating benign and malignant breast lesions. The clinical trial was conducted at the Tan Tock Seng hospital, Singapore. 103 women scheduled for mammography and/or ultrasound tests participated in the study. The BDS test recorded a sensitivity of 100%, specificity of 97.6%, and an accuracy of 98.1%. The area under the ROC curve was 0.988 which was slightly lower than that of ultrasound (0.994) and slightly higher than that of mammography (0.951). The BDS test has demonstrated high sensitivity and specificity values in the studied population. The accuracy is also comparable to that of diagnostic techniques like mammography and ultrasound. Thus, it is evident that BDS can be a fast and reliable adjunct tool for getting a secondary opinion on lesions with indeterminate mammographic and sonographic results.

  15. Bodily Distress Syndrome

    DEFF Research Database (Denmark)

    Budtz-Lilly, Anna; Vestergaard, Mogens; Moth, Grete;

    2011-01-01

    , and their interpretation of the content of the contact. The patients were asked to complete questionnaires on symptom score for BDS, self evaluated health (SF-12), mental health (Symptom Check List: SCL), health anxiety (Whiteley-7), smoking, alcohol dependency (CAGE) and patient evaluation of practice (DanPEP). Results...

  16. 76 FR 19996 - Cooperative Agreement With the University of Mississippi's National Center for Natural Products...

    Science.gov (United States)

    2011-04-11

    ... and dissemination of natural products research and science and the programs developed under the... of a list of BDS and botanical ingredients, based on safety concerns, trends, and knowledge of... characterize authenticated reference materials, including raw and processed plant materials and...

  17. A Statistical Study of Brown Dwarf Companions from the SDSS-III MARVELS Survey

    Science.gov (United States)

    Grieves, Nolan; Ge, Jian; Thomas, Neil; Ma, Bo; De Lee, Nathan M.; Lee, Brian L.; Fleming, Scott W.; Sithajan, Sirinrat; Varosi, Frank; Liu, Jian; Zhao, Bo; Li, Rui; Agol, Eric; MARVELS Team

    2016-01-01

    We present 23 new Brown Dwarf (BD) candidates from the Multi-object APO Radial-Velocity Exoplanet Large-Area Survey (MARVELS) of the Sloan Digital Sky Survey III (SDSS-III). The BD candidates were selected from the processed MARVELS data using the latest University of Florida 2D pipeline, which shows significant improvement and reduction of systematic errors over the 1D pipeline results included in the SDSS Data Release 12. This sample is the largest BD yield from a single radial velocity survey. Of the 23 candidates, 18 are around main sequence stars and 5 are around giant stars. Given a giant contamination rate of ~24% for the MARVELS survey, we find a BD occurrence rate around main sequence stars of ~0.7%, which agrees with previous studies and confirms the BD desert, while the BD occurrence rate around the MARVELS giant stars is ~0.6%. Preliminary results show that our new candidates around solar type stars support a two population hypothesis, where BDs are divided at a mass of ~42.5 MJup. BDs less massive than 42.5 MJup have eccentricity distributions consistent with planet-planet scattering models, where BDs more massive than 42.5 MJup have both period and eccentricity distributions similar to that of stellar binaries. Special Brown Dwarf systems such as multiple BD systems and highly eccentric BDs will also be presented.

  18. The Open Service Signal in Space Navigation Data Comparison of the Global Positioning System and the BeiDou Navigation Satellite System

    Directory of Open Access Journals (Sweden)

    Shau-Shiun Jan

    2014-08-01

    Full Text Available More and more Global Navigation Satellite Systems (GNSSs have been developed and are in operation. Before integrating information on various GNSSs, the differences between the various systems must be studied first. This research focuses on analyzing the navigation data differences between the Chinese BeiDou Navigation Satellite System (BDS and the United States’ Global Positioning System (GPS. In addition to explaining the impact caused by these two different coordinate and time systems, this research uses an actual open service signal in space (SIS for both GPS and BDS to analyze their current system performance. Five data quality analysis (DQA mechanisms are proposed in this research to validate both systems’ SIS navigation data. These five DQAs evaluate the differences in ephemeris and almanac messages from both systems for stability and accuracy. After all of the DQAs, the different issues related to GPS and BDS satellite information are presented. Finally, based on these DQA results, this research provides suggested resolutions for the combined use of GPS and BDS for navigation and guidance.

  19. Bubble detector's evaluation for neutron field measurement in a very known source

    Energy Technology Data Exchange (ETDEWEB)

    Ramalho, Eduardo; Silva, Ademir X. da, E-mail: ademir@nuclear.ufrj.b, E-mail: jdantas@con.ufrj.b [Coordenacao dos Programas de Pos-Graduacao de Engenharia (PEN/COPPE/UFRJ), RJ (Brazil). Programa de Engenharia Nuclear; Reina, Luiz, E-mail: reina@ien.gov.b [Instituto de Engenharia Nuclear (IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil); Facure, Alessandro, E-mail: facure@cnen.gov.b [Comissao Nacional de Energia Nuclear (CNEN), Rio de Janeiro, RJ (Brazil)

    2011-07-01

    Measurements on neutron fields, mainly for dosimetric purposes, have been a major concern for ionizing radiation workers, because of the radiation protection issues. The present work aims to study the using of bubble detectors in neutron dosimetry and the Bubble Detector Spectrometer (BDS) was chosen for this task. Several experiments were performed in order to obtain spectra from such devices and their respective analysis and then they were compared to those which were obtained by other ways. An Am-Be calibration neutron source from Instituto de Radioprotecao e Dosimetria/Comissao Nacional de Energia Nuclear (IRD/CNEN) was used and its spectrum was compared to the one obtained by BDS. The possibility of the use of such devices as ambient dosimeters was also evaluated. Despite the uncertainties, especially in the lowest energy thresholds, the spectrum from BDS is in good agreement with the known ones and the use of BDS as a dosimeter demands a more detailed study due to some characteristics of the Am-Be source that produce high uncertainties in low energy thresholds. (author)

  20. The open service signal in space navigation data comparison of the Global Positioning System and the BeiDou Navigation Satellite System.

    Science.gov (United States)

    Jan, Shau-Shiun; Tao, An-Lin

    2014-08-19

    More and more Global Navigation Satellite Systems (GNSSs) have been developed and are in operation. Before integrating information on various GNSSs, the differences between the various systems must be studied first. This research focuses on analyzing the navigation data differences between the Chinese BeiDou Navigation Satellite System (BDS) and the United States' Global Positioning System (GPS). In addition to explaining the impact caused by these two different coordinate and time systems, this research uses an actual open service signal in space (SIS) for both GPS and BDS to analyze their current system performance. Five data quality analysis (DQA) mechanisms are proposed in this research to validate both systems' SIS navigation data. These five DQAs evaluate the differences in ephemeris and almanac messages from both systems for stability and accuracy. After all of the DQAs, the different issues related to GPS and BDS satellite information are presented. Finally, based on these DQA results, this research provides suggested resolutions for the combined use of GPS and BDS for navigation and guidance.

  1. Microlensing discovery of a population of very tight, very low mass binary brown dwarfs

    DEFF Research Database (Denmark)

    Choi, J.-Y.; Han, C.; Udalski, A.;

    2013-01-01

    Although many models have been proposed, the physical mechanisms responsible for the formation of low-mass brown dwarfs (BDs) are poorly understood. The multiplicity properties and minimum mass of the BD mass function provide critical empirical diagnostics of these mechanisms. We present the disc...

  2. The use of skin surface electropotentials for breast cancer detection--preliminary clinical trial results obtained using the biofield diagnostic system.

    Science.gov (United States)

    Sree, Subbhuraam Vinitha; Ng, E Y K; Kaw, G; U, Rajendra Acharya; Chong, B K

    2011-02-01

    The purpose of this study is to evaluate the efficiency of the Biofield Diagnostic System (BDS) as an adjunct to established diagnostic techniques such as mammography and ultrasound in differentiating benign and malignant breast lesions. The clinical trial was conducted at the Tan Tock Seng hospital, Singapore. 103 women scheduled for mammography and/or ultrasound tests participated in the study. The BDS test recorded a sensitivity of 100%, specificity of 97.6%, and an accuracy of 98.1%. The area under the ROC curve was 0.988 which was slightly lower than that of ultrasound (0.994) and slightly higher than that of mammography (0.951). The BDS test has demonstrated high sensitivity and specificity values in the studied population. The accuracy is also comparable to that of diagnostic techniques like mammography and ultrasound. Thus, it is evident that BDS can be a fast and reliable adjunct tool for getting a secondary opinion on lesions with indeterminate mammographic and sonographic results. PMID:20703583

  3. Clinical Implications of DSM-IV Subtyping of Bipolar Disorders in Referred Children and Adolescents

    Science.gov (United States)

    Masi, Gabriele; Perugi, Giulio; Millepiedi, Stefania; Mucci, Maria; Pari, Cinzia; Pfanner, Chiara; Berloffa, Stefano; Toni, Cristina

    2007-01-01

    Objective: According to DSM-IV, bipolar disorders (BDs) include four subtypes, BD I, BD II, cyclothymic disorder, and BD not otherwise specified (NOS). We explore the clinical implications of this subtyping in a naturalistic sample of referred youths with BD I, BD II, and BD-NOS. Method: The sample consisted of 217 patients, 135 males and 82…

  4. Relation between Brown Dwarfs and Exoplanets

    CERN Document Server

    Torres, Lauren Melissa Flor; Schröeder, Klauss-Peter; Caretta, César A; Jack, Dennis

    2016-01-01

    One of the most debated subjects in Astronomy since the discovery of exoplanets is how can we distinguish the most massive of such objects from very-low mass stars like Brown Dwarfs (BDs)? We have been looking for evidences of a difference in physical characteristics that could be related to different formation processes. Using a new diagnostic diagram that compares the baryonic gravitational potential (BGP) with the distances from their host stars, we have classified a sample of 355 well-studied exoplanets according to their possible structures. We have then compared the exoplanets to a sample of 87 confirmed BDs, identifying a range in BGP that could be common to both objects. By analyzing the mass-radius relations (MRR) of the exoplanets and BDs in those different BGP ranges, we were able to distinguish different characteristic behaviors. By comparing with models in the literature, our results suggest that BDs and massive exoplanets might have similar structures dominated by liquid metallic hydrogen (LMH).

  5. BeiDou Time Transfer With the Standard CGGTTS.

    Science.gov (United States)

    Huang, Wei; Defraigne, Pascale

    2016-07-01

    The R2CGGTTS software tool developed at the Royal Observatory of Belgium (ROB) to provide clock solutions in the standard Common GNSS Generic Time Transfer Standard (CGGTTS) has been extended to BeiDou Navigation Satellite System (BDS). The BDS includes satellites in three different orbits: 1) Medium Earth Orbit (MEO); 2) Inclined Geosynchronous Satellite Orbit (IGSO); and 3) Geostationary Earth Orbit (GEO). This paper presents first results obtained with this upgraded software, and a comparison between common view (CV) time transfer solutions obtained with either BDS, or GPS or Galileo. These preliminary results indicate that the BeiDou MEO satellites give time transfer results with a higher noise than the GPS results. This additional noise is shown to be due to some elevation-dependent delay in the BDS code measurements. Some biases were furthermore pointed out between the CV results obtained with the different BeiDou MEO satellites when the receivers used in the two stations are of different make. These biases may reach some nanoseconds, and find most probably their origin in the receiver hardware or firmware. It is shown additionally that using the BeiDou IGSO satellites and the GEO satellites, although increasing the number of observations, especially in the Asia-Pacific region, introduces a significant time transfer noise in the CV results. PMID:26766373

  6. Importance of clinical posting for awareness on bio-medical waste in medical and paramedical students

    Directory of Open Access Journals (Sweden)

    Jemil S Makadia

    2014-10-01

    Full Text Available Background: The management of health care waste is the subject of considerable concern to public health. Unscientific disposal of health care waste may lead to the transmission of communicable disease which is a risk for health care professionals. Objective: The main objective of this study was to assess the awareness in the medical and paramedical students about bio-medical waste (BMW hazards and management and to see the impact of clinical posting in knowledge regarding BMW handling. Materials and Methods: This was a cross-sectional type of study. A total of 240 subjects was enrolled, 60 each from 1 st year students of MBBS, BDS, nursing, and MLT. They were interviewed for health care waste management practices. Results: Study shows overall awareness regarding BMW in nursing and MLT students were better than MBBS and BDS students. We found that about the infection like HIV almost all the students were equally aware but awareness about hepatitis B infection was more in MBBS and BDS students and also in nursing students compared with MLT students. All the students from four groups were almost vaccinated for tetanus toxoid but only 50% students were vaccinated for hepatitis B. Conclusion: The nursing and MLT students comparatively were having better knowledge and attitude than BDS and MBBS students in many aspects. However, overall knowledge of 1 st year students from all the groups was not satisfactory and number of students those who were vaccinated for hepatitis B was also low which put them at risk.

  7. Applications of two-way satellite time and frequency transfer in the BeiDou navigation satellite system

    Science.gov (United States)

    Zhou, ShanShi; Hu, XiaoGong; Liu, Li; Guo, Rui; Zhu, LingFeng; Chang, ZhiQiao; Tang, ChengPan; Gong, XiuQiang; Li, Ran; Yu, Yang

    2016-10-01

    A two-way satellite time and frequency transfer (TWSTFT) device equipped in the BeiDou navigation satellite system (BDS) can calculate clock error between satellite and ground master clock. TWSTFT is a real-time method with high accuracy because most system errors such as orbital error, station position error, and tropospheric and ionospheric delay error can be eliminated by calculating the two-way pseudorange difference. Another method, the multi-satellite precision orbit determination (MPOD) method, can be applied to estimate satellite clock errors. By comparison with MPOD clock estimations, this paper discusses the applications of the BDS TWSTFT clock observations in satellite clock measurement, satellite clock prediction, navigation system time monitor, and satellite clock performance assessment in orbit. The results show that with TWSTFT clock observations, the accuracy of satellite clock prediction is higher than MPOD. Five continuous weeks of comparisons with three international GNSS Service (IGS) analysis centers (ACs) show that the reference time difference between BeiDou time (BDT) and golbal positoning system (GPS) time (GPST) realized IGS ACs is in the tens of nanoseconds. Applying the TWSTFT clock error observations may obtain more accurate satellite clock performance evaluation in the 104 s interval because the accuracy of the MPOD clock estimation is not sufficiently high. By comparing the BDS and GPS satellite clock performance, we found that the BDS clock stability at the 103 s interval is approximately 10-12, which is similar to the GPS IIR.

  8. X-ray emission from the young brown dwarfs of the Taurus Molecular Cloud

    CERN Document Server

    Grosso, N; Güdel, M; Guieu, S; Franciosini, E; Palla, F; Dougados, C; Monin, J L; Ménard, F; Bouvier, J; Audard, M; Telleschi, A

    2006-01-01

    The XMM-Newton Extended Survey of the TMC (XEST) is a large program designed to systematically investigate the X-ray properties of young stellar/substellar objects in the TMC. In particular, the area surveyed by 15 XMM-Newton pointings (of which three are archival observations), supplemented with one archival Chandra observation, allows us to study 17 BDs with M spectral types. Half of this sample (9 out of 17 BDs) is detected; 7 BDs are detected here for the first time in X-rays. We observed a flare from one BD. We confirm several previous findings on BD X-ray activity: a log-log relation between X-ray and bolometric luminosity for stars (with L*<10 Lsun) and BDs detected in X-rays; a shallow log-log relation between X-ray fractional luminosity and mass; a log-log relation between X-ray fractional luminosity and effective temperature; a log-log relation between X-ray surface flux and effective temperature. We find no significant log-log correlation between the X-ray fractional luminosity and EW(Halpha). A...

  9. Myalgic encephalomyelitis: International Consensus Criteria

    OpenAIRE

    Carruthers, B M; van de Sande, M I; De Meirleir, K L; Klimas, N G; Broderick, G; MITCHELL, T; Staines, D.; Powles, A C P; Speight, N; Vallings, R; Bateman, L; Baumgarten-Austrheim, B; Bell, D. S.; N. Carlo-Stella; Chia, J

    2011-01-01

    Carruthers BM, van de Sande MI, De Meirleir KL, Klimas NG, Broderick G, Mitchell T, Staines D, Powles ACP, Speight N, Vallings R, Bateman L, Baumgarten-Austrheim B, Bell DS, Carlo-Stella N, Chia J, Darragh A, Jo D, Lewis D, Light AR, Marshall-Gradisbik S, Mena I, Mikovits JA, Murovska M, Pall ML, Stevens S (Independent, Vancouver, BC, Canada; Independent, Calgary, AB, Canada; Department of Physiology and Medicine, Vrije University of Brussels, Himmunitas Foundation, Brussels, Belgium; Departm...

  10. The Leaf-Beetles (Coleoptera, Chrysomelidae) Feed On Some Weeds In Tokat Province

    OpenAIRE

    Çam, Halit; ATAY, Turgut

    2004-01-01

    This study was carried out to determine the leaf-beetles (Coleoptera, Chrysomelidae) which causes extensive damage on weeds in the vicinity of Tokat, Turkey. Total 9 taxa including 4 species of Chrysomelinae, 1 species of Clytrinae, 1 species of Criocerinae, 2 species of Alticinae and 1 species of Cassidinae were found to be destructive on different weed species. These species were; Entomoscelis adonidis (Pall.) on Sinapis arvensis L., Gastrophysa polygoni (L.) on Polygonum convolvulus L. an...

  11. Kui video võiks tappa... : noppeid Prantsuse-Balti ja Põhjamaade meediakunsti festivalilt / Anders Härm

    Index Scriptorium Estoniae

    Härm, Anders, 1977-

    1998-01-01

    Festivali 'offline@online' kuraatorid Raivo Kelomees, Tiia Johannson. Pierre Yves Clouini videotest, Palle Torssoni arvutimängul Duke Nukem 3D baseeruvast tööst. Eesti kunstnikest on Duke Nukem'it kasutanud Lennart Mänd, Mart Viljus. Kanada kuraatori Stephen Kovatsi rahvusvahelisest projektist 'Ostranenie'. Andras Solymoni, Natalia Borissova, Olli Mannerkoski töödest. Lev Manovichi püstitatud küsimusest interface'ist

  12. Is the Air Handling Capability of the Quadrox D Pump Dependent within an ECMO Circuit? An In Vitro Study

    OpenAIRE

    Gill, Martin C.; Dando, Hayden; Dittmer, John

    2010-01-01

    The occurrence of gaseous microemboli (GME) within the extracorporeal membrane oxygenation circuit is largely overlooked, as are methods to ameliorate this occurrence. We aimed to determine if the air handling capability of the Quadrox D oxygenator was dependent upon whether it was used in conjunction with a centrifugal or roller pump; and if application of a Pall air eliminating filter (AEF) would prevent circuit air introduction from intravenous infusions. Using a blood primed circuit 1 mL ...

  13. Ecological and morphological studies in the hybrid zone between Pinus sibirica and Pinus pumila

    OpenAIRE

    S.N. Goroshkevich; Popov, A. G.; G.V. Vasilieva

    2013-01-01

    In the Baikal Region, there is no phenological isolation between Siberian stone pine (P. sibirica Du Tour) and Siberian dwarf stone pine (P. pumila (Pall.) Regel) since the timing of their 'flowering' coincides. Morphologically intermediate individuals, supposedly natural hybrids,occur not very often. In the west half of Stanovoye upland area four regions were investigated: Barguzinskiy, Baikalskiy, Verchneangarskiy and the Severo-Myiskiy mountain ridges. Interspecific natural hybridization w...

  14. Comparison of anatomical characteristics of leaves and flowers of Crataegus and some species of Rosaceae family

    OpenAIRE

    V.A. Kiryanova; E.U. Babaeva

    2014-01-01

    The present work shows the results of microscopy of Crataegus sanguinea Pall. leaves with flowers (Crataegi flores cum folia), which is considered as a perspective form of medicinal raw material, and the hypothetical plant adulterants – Amelanchier ovalis Medik., Prunus subgen. Cerasus (Mill.) A. Gray, Pyrus communis L., Aronia melanocarpa (Michx.) Elliott (Rosaceae). Parts of leaves and flowers of stated plants were subjected to anatomical investigation and comparative studies. Microscopical...

  15. Gud eller Svensson : om en teori för psykos och utveckling av en behandlingsmetod

    OpenAIRE

    Edenius, Bo

    1999-01-01

    The two principal elements comprising this thesis are 1) a description of the development of a theory concerning schizophrenic psychosis and 2) an attempt to develop a treatment strategy based on this theory. The theory was developed by Palle Villemoes on the basis of the French psychoanalyst Lacan's work and may be described as an ego-structuring psychotherapy with its foundation in the castration complex. The psychosis is seen as a consequence of the child's inability, for various reasons, ...

  16. Complete robotic inspection line using PC-based control, supervision and parameterization software

    OpenAIRE

    Norberto Pires, J.; Paulo, Sérgio

    2005-01-01

    Non-flat ceramic products, like toilets and bidets, are fully inspected at the end of the production process, to search for structural, surface and functional defects. Ceramic pieces are transported to the inspection lines assembled in pallets, carried by electro-mechanical fork-lifters or automatic guided vehicles. Pallets need to be disassembled, while feeding with the inspection lines where human operators execute the inspection tasks. Also, the pieces that pass inspection need to be palle...

  17. Comercialización de semillas (variedades e híbridos) importadas de pimentón Capsicum annuum L en Colombia en el periodo enero 1990-agosto 1994

    OpenAIRE

    Lema Nuñez Rosario M.

    1996-01-01

    <p>All the companies that produce varieties of paprika are North American, and due to the strong economic force of 4 or 5, dominate the market. These oligopolies diferenciate the seeds in quality, brand and packaging and in this way restrict other new companies entering the market. Reputable brands of quality (Petoseed, Asgrow and Rogers NK) are the sole producers of hybrid seeds. The difference in price of befween the hybrid paprika seed and the Californian wonder type is substantial. ...

  18. Løkke lykkes

    DEFF Research Database (Denmark)

    Bengtsson, Mette

    2011-01-01

    Næsten alle er enige: Statsministerens nytårstale var stærk. Lars Løkke Rasmussen er ikke en mand, der normalt høster ros som den store taler, men hans nytårstale lykkes retorisk. Talen giver mindelser om Reagans slogans, Voltaires ordsprog, Krønikens Palle From – og så har den suspense. Men...

  19. Näitused kunstiakadeemias

    Index Scriptorium Estoniae

    2003-01-01

    EKA galeriis näitusel "Kirju pall" esitavad "krutskilist ökokunsti" rühmitus Puhas Rõõm, Mart Viljus, Anu Vahtra, Maris Mändel, Katrin Tees, Reimo Võsa-Tangsoo, Erki Kasemets, Raivo Hool. Aula fuajees näeb Jaak Soansi juhendamisel valminud skulptuuriosakonna õppetöid, valdavalt poliitikute skulptuurportreid. Osalevad Kristiina Järvelaid, Jelena Levtshenkova, Rene Reinumäe, Kaisa Uusoksa, Marju Vaher

  20. Accumulation of moisture and soil erosion in the territory of social vole ( Microtus socialis) settlements in the northern Caspian Lowland

    Science.gov (United States)

    Bykov, A. V.; Kolesnikov, A. V.; Kulakova, N. Yu.; Shabanova, N. P.

    2008-08-01

    In the clay semidesert of the Caspian Lowland, the surface runoff is transformed to soil runoff due to the presence of a system of social vole ( Microtus socialis Pall.) passageways in the soils that promotes the retention of soil moisture and prevents the development of soil erosion. A quantitative assessment of this process is given. We describe the mechanism of intense soil erosion arising after the disturbance of vole underground passageways responsible for the formation of specific relief elements and plant communities.

  1. Nonthyroidal illness syndrome in patients with subarachnoid hemorrhage due to intracranial aneurysm

    Directory of Open Access Journals (Sweden)

    Casulari Luiz Augusto

    2004-01-01

    Full Text Available We have previously reported that subarachnoid hemorrhage due to ruptured intracranial aneurysm (SH is associated with changes in the hormonal profile in the first 24 hours after the event. We proposed that the hormonal changes observed are due to the intense stress to which the patients are exposed. However, the thyroidal hormonal profile is indicative of the presence of a nonthyroidal illness syndrome (NTIS. In this paper, we examined whether the change in the thyroid hormone profile is compatible with a NTIS. Two groups of patients were included in the study: A 30 patients with SH (21 females and 9 males; 41.7±11.4 years and B a control group including 25 patients with benign diseases of the spine (BDS (lumbar disc hernia or stable spinal trauma (8 females and 17 males; 41.3±14.2 years. In a subgroup of eight patients of each group serum triiodothyronine (T3 and reverse T3 levels were measured. The blood samples were obtained between 8:00 and 9:00 AM. The following results were obtained: The SH group had smaller serum T3 and free T4 levels than the BDS group (p<0.05: T3 (ng/mL: SH = 58.7±1.1 and BDS = 74.5±13.9; free T4 (ng/dL: SH = 0.9±0.2 and BDS = 1.1±0.3. There was no significant difference in the serum levels of total thyroxine (T4 and thyroid-stimulating hormone (TSH between the two groups: T4 (µg/dL: SH = 6.9±1.1 and BDS = 7.4±2.1; TSH (µUI/mL: SH = 1.5±0.8 and BDS = 1.8±1,0. In the sample of eight patients of each group we had the following results: T3 (ng/mL: SH = 66.8±3.8 and BDS = 77.2±1.1 (p <0.05; reverse T3 (ng/dL: SH = 32.8±8 and BDS = 24.7±2.2 (NS; T3/ reverse T3 ratio: SH = 2.6±0.3 and BDS = 3.3±0.4 (NS. Thyreoglobulin and microsomal antibodies were not detectable, except in one patient in the SH group. In conclusion, the SH patients present serum levels of T3 and free T4 significantly lower than that of BDS patients; the thyroidal hormone profile suggests that SH patients have developed the nonthyroidal

  2. Designing and Validating Ternary Pd Alloys for Optimum Sulfur/Carbon Resistance in Hydrogen Separation and Carbon Capture Membrane Systems Using High-Throughput Combinatorial Methods

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, Amanda; Zhao, Hongbin; Hopkins, Scott

    2014-09-30

    This report summarizes the work completed under the U.S. Department of Energy Project Award No.: DE-FE0001181 titled “Designing and Validating Ternary Pd Alloys for Optimum Sulfur/Carbon Resistance in Hydrogen Separation and Carbon Capture Membrane Systems Using High-Throughput Combinatorial Methods.” The project started in October 1, 2009 and was finished September 30, 2014. Pall Corporation worked with Cornell University to sputter and test palladium-based ternary alloys onto silicon wafers to examine many alloys at once. With the specialized equipment at Georgia Institute of Technology that analyzed the wafers for adsorbed carbon and sulfur species six compositions were identified to have resistance to carbon and sulfur species. These compositions were deposited on Pall AccuSep® supports by Colorado School of Mines and then tested in simulated synthetic coal gas at the Pall Corporation. Two of the six alloys were chosen for further investigations based on their performance. Alloy reproducibility and long-term testing of PdAuAg and PdZrAu provided insight to the ability to manufacture these compositions for testing. PdAuAg is the most promising alloy found in this work based on the fabrication reproducibility and resistance to carbon and sulfur. Although PdZrAu had great initial resistance to carbon and sulfur species, the alloy composition has a very narrow range that hindered testing reproducibility.

  3. An Orally Active Cannabis Extract with High Content in Cannabidiol attenuates Chemically-induced Intestinal Inflammation and Hypermotility in the Mouse

    Science.gov (United States)

    Pagano, Ester; Capasso, Raffaele; Piscitelli, Fabiana; Romano, Barbara; Parisi, Olga A.; Finizio, Stefania; Lauritano, Anna; Marzo, Vincenzo Di; Izzo, Angelo A.; Borrelli, Francesca

    2016-01-01

    Anecdotal and scientific evidence suggests that Cannabis use may be beneficial in inflammatory bowel disease (IBD) patients. Here, we have investigated the effect of a standardized Cannabis sativa extract with high content of cannabidiol (CBD), here named CBD BDS for “CBD botanical drug substance,” on mucosal inflammation and hypermotility in mouse models of intestinal inflammation. Colitis was induced in mice by intracolonic administration of dinitrobenzenesulfonic acid (DNBS). Motility was evaluated in the experimental model of intestinal hypermotility induced by irritant croton oil. CBD BDS or pure CBD were given - either intraperitoneally or by oral gavage – after the inflammatory insult (curative protocol). The amounts of CBD in the colon, brain, and liver after the oral treatments were measured by high-performance liquid chromatography coupled to ion trap-time of flight mass spectrometry. CBD BDS, both when given intraperitoneally and by oral gavage, decreased the extent of the damage (as revealed by the decrease in the colon weight/length ratio and myeloperoxidase activity) in the DNBS model of colitis. It also reduced intestinal hypermotility (at doses lower than those required to affect transit in healthy mice) in the croton oil model of intestinal hypermotility. Under the same experimental conditions, pure CBD did not ameliorate colitis while it normalized croton oil-induced hypermotility when given intraperitoneally (in a dose-related fashion) or orally (only at one dose). In conclusion, CBD BDS, given after the inflammatory insult, attenuates injury and motility in intestinal models of inflammation. These findings sustain the rationale of combining CBD with other minor Cannabis constituents and support the clinical development of CBD BDS for IBD treatment. PMID:27757083

  4. New models and predictions for Brownian coagulation of non-interacting spheres.

    Science.gov (United States)

    Kelkar, Aniruddha V; Dong, Jiannan; Franses, Elias I; Corti, David S

    2013-01-01

    The classical steady-state Smoluchowski model for Brownian coagulation is evaluated using Brownian Dynamics Simulations (BDS) as a benchmark. The predictions of this approach compare favorably with the results of BDS only in the dilute limit, that is, for volume fractions of φ≤5×10(-4). From the solution of the more general unsteady-state diffusion equation, a new model for coagulation is developed. The resulting coagulation rate constant is time-dependent and approaches the steady-state limit only at large times. Moreover, in contrast to the Smoluchowski model, this rate constant depends on the particle size, with the transient effects becoming more significant at larger sizes. The predictions of the unsteady-state model agree well with the BDS results up to volume fractions of about φ=0.1, at which the aggregation half-time predicted by the Smoluchowski model is five times that of the BDS. A new procedure to extract the aggregation rate constant from simulation results based on this model is presented. The choice of the rate constant kernel used in the population balance equations for complete aggregation is also evaluated. Extension of the new model to a variable rate constant kernel leads to increased accuracy of the predictions, especially for φ≤5×10(-3). This size-dependence of the rate constant kernel affects particularly the predictions for initially polydisperse sphere systems. In addition, the model is extended to account in a novel way for both short-range viscous two-particle interactions and long-range many-particle Hydrodynamic Interactions (HI). Predictions including HI agree best with the BDS results. The new models presented here offer accurate and computationally less-intensive predictions of the coagulation dynamics while also accounting for hydrodynamic coupling. PMID:23036339

  5. Precise orbit determination for quad-constellation satellites at Wuhan University: strategy, result validation, and comparison

    Science.gov (United States)

    Guo, Jing; Xu, Xiaolong; Zhao, Qile; Liu, Jingnan

    2016-02-01

    This contribution summarizes the strategy used by Wuhan University (WHU) to determine precise orbit and clock products for Multi-GNSS Experiment (MGEX) of the International GNSS Service (IGS). In particular, the satellite attitude, phase center corrections, solar radiation pressure model developed and used for BDS satellites are addressed. In addition, this contribution analyzes the orbit and clock quality of the quad-constellation products from MGEX Analysis Centers (ACs) for a common time period of 1 year (2014). With IGS final GPS and GLONASS products as the reference, Multi-GNSS products of WHU (indicated by WUM) show the best agreement among these products from all MGEX ACs in both accuracy and stability. 3D Day Boundary Discontinuities (DBDs) range from 8 to 27 cm for Galileo-IOV satellites among all ACs' products, whereas WUM ones are the largest (about 26.2 cm). Among three types of BDS satellites, MEOs show the smallest DBDs from 10 to 27 cm, whereas the DBDs for all ACs products are at decimeter to meter level for GEOs and one to three decimeter for IGSOs, respectively. As to the satellite laser ranging (SLR) validation for Galileo-IOV satellites, the accuracy evaluated by SLR residuals is at the one decimeter level with the well-known systematic bias of about -5 cm for all ACs. For BDS satellites, the accuracy could reach decimeter level, one decimeter level, and centimeter level for GEOs, IGSOs, and MEOs, respectively. However, there is a noticeable bias in GEO SLR residuals. In addition, systematic errors dependent on orbit angle related to mismodeled solar radiation pressure (SRP) are present for BDS GEOs and IGSOs. The results of Multi-GNSS combined kinematic PPP demonstrate that the best accuracy of position and fastest convergence speed have been achieved using WUM products, particularly in the Up direction. Furthermore, the accuracy of static BDS only PPP degrades when the BDS IGSO and MEO satellites switches to orbit-normal orientation

  6. Implications of multi-Regge limits for the Bern-Dixon-Smirnov conjecture

    CERN Document Server

    Brower, Richard C; Schnitzer, Howard J; Tan, Chung-I

    2008-01-01

    Planar ${\\cal N} =4$ super Yang-Mills SU(N) theory is expected to exhibit string behavior, anticipated by the 't Hooft genus expansion and the $AdS/CFT$ correspondence. We examine the Bern-Dixon-Smirnov (BDS) conjecture for $n$-gluon amplitudes in the context of Regge and multi-Regge limits. The $n=4$ and $n=5$ amplitudes obey the expected Regge form, while the amplitudes for $n \\ge 6$ do not. This failure is interpreted as strong evidence that the BDS conjecture is not correct for $n \\ge 6$. Significant problems also emerge for the conjectured conformal Ward identity and/or the gluon scattering amplitude/ Wilson loop duality at strong coupling.

  7. A novel MOCVD reactor for growth of high-quality GaN-related LED layers

    Science.gov (United States)

    Hu, Shaolin; Liu, Sheng; Zhang, Zhi; Yan, Han; Gan, Zhiyin; Fang, Haisheng

    2015-04-01

    Gallium nitride (GaN), a direct bandgap semiconductor widely used in bright light-emitting diodes (LEDs), is mostly grown by metal-organic chemical vapor deposition (MOCVD) method. A good reactor design is critical for the production of high-quality GaN thin films. In this paper, we presented a novel buffered distributed spray (BDS) MOCVD reactor with vertical gas sprayers and horizontal gas inlets. Experiments based on a 36×2″ BDS reactor were conducted to examine influence of the process parameters, such as the operating pressure and the gas flow rate, on the growth efficiency and on the layer thickness uniformity. Transmission electron microscopy (TEM) and photoluminescence (PL) are further conducted to evaluate quality of the epitaxial layers and to check performance of the reactor. Results show that the proposed novel reactor is of high performance in growing high-quality thin films, including InGaN/GaN multiquantum wells (MQWs) structures.

  8. 高效液相色谱法定量测定鸵鸟油中的EPA、DPA%DETERMINATION OF EPA AND DPA IN OSTRICH OIL BY HPLC

    Institute of Scientific and Technical Information of China (English)

    杨秀芳; 闫倩茹; 伍发云

    2011-01-01

    High Performance Liquid Chromatography (HPLC) was used to identified and determine the polyunsaturated fatty acid (PUFA)of Ostrich oil. The sample was analyzed using pre-column derivation, on Hypersil BDS C18 column and assayed by 252 nm UV detector,the composing and contends of EPA ^DPA in Ostrich oil was determined well.%应用高效液相色谱(HPLC)法对鸵鸟油脂肪酸中多不饱和脂肪酸组成进行了定性定量分析.采用α-溴苯乙酮为衍生化试剂,应用Hypersil BDS C18柱,252 nm紫外检测,能很好地分析鸵鸟油脂肪酸中EPA、DPA的组成和含量.

  9. Toxicity evaluation of 2-hydroxybiphenyl and other compounds involved in studies of fossil fuels biodesulphurisation.

    Science.gov (United States)

    Alves, L; Paixão, S M

    2011-10-01

    The acute toxicity of some compounds used in fossil fuels biodesulphurisation studies, on the respiration activity, was evaluated by Gordonia alkanivorans and Rhodococcus erythropolis. Moreover, the effect of 2-hydroxybiphenyl on cell growth of both strains was also determined, using batch (chronic bioassays) and continuous cultures. The IC₅₀ values obtained showed the toxicity of all the compounds tested to both strains, specially the high toxicity of 2-HBP. These results were confirmed by the chronic toxicity data. The toxicity data sets highlight for a higher sensitivity to the toxicant by the strain presenting a lower growth rate, due to a lower cells number in contact with the toxicant. Thus, microorganisms exhibiting faster generation times could be more resistant to 2-HBP accumulation during a BDS process. The physiological response of both strains to 2-HBP pulse in a steady-state continuous culture shows their potential to be used in a future fossil fuel BDS process.

  10. BFKL Pomeron, Reggeized gluons and Bern-Dixon-Smirnov amplitudes

    Energy Technology Data Exchange (ETDEWEB)

    Bartels, J. [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik; Lipatov, L.N. [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik]|[St. Petersburg Nuclear Physics Institute (Russian Federation); Sabio Vera, A. [CERN, Geneva (Switzerland)

    2008-02-15

    After a brief review of the BFKL approach to Regge processes in QCD and in supersymmetric (SUSY) gauge theories we propose a strategy for calculating the next-to-next-to-leading order corrections to the BFKL kernel. They can be obtained in terms of various cross-sections for Reggeized gluon interactions. The corresponding amplitudes can be calculated in the framework of the effective action for high energy scattering. In the case of N=4 SUSY it is also possible to use the Bern-Dixon-Smirnov (BDS) ansatz. For this purpose the analytic properties of the BDS amplitudes at high energies are investigated, in order to verify their self-consistency. It is found that, for the number of external particles being larger than five, these amplitudes, beyond one loop, are not in agreement with the BFKL approach which predicts the existence of Regge cuts in some physical channels. (orig.)

  11. 1,25-Dihydroxyvitamin-D3 Induces Avian β-Defensin Gene Expression in Chickens

    Science.gov (United States)

    Zhang, Guolong; Ouyang, Linghua; Robinson, Kelsy; Tang, Yanqiang; Zhu, Qing; Li, Diyan; Hu, Yaodong; Liu, Yiping

    2016-01-01

    Host defense peptides (HDPs) play a critical role in innate immunity. Specific modulation of endogenous HDP synthesis by dietary compounds has been regarded as a novel approach to boost immunity and disease resistance in animal production. 1,25-dihydroxy vitamin D3 (1,25D3) is well known as a powerful HDP inducer in humans, but limited information about the effect of 1,25D3 on HDPs in poultry is available. Here, we sought to examine whether 1,25D3 could stimulate avian β-defensin (AvBD) expression in chickens. We used chicken embryo intestinal epithelial cells (CEIEPCs) and peripheral blood mononuclear cells (PBMCs) to study the effect of 1,25D3 on the expression of AvBDs. We observed that 1,25D3 is able to up-regulate the expression of several AvBDs in CEIEPCs and PBMCs, whereas it increased the amounts of AvBD4 mRNA in CEIEPCs only in the presence of lipopolysaccharide (LPS). On the other hand, LPS treatment not only inhibited the expression of CYP24A1 but also altered the expression pattern of VDR in CEIEPCs. Furthermore, AvBDs were not directly regulated by 1,25D3, as cycloheximide completely blocked 1,25D3-induced expression of AvBDs. Our observations suggest that 1,25D3 is capable of inducing AvBD gene expression and is a potential antibiotic alternative through augmentation of host innate immunity as well as disease control in chickens. PMID:27135828

  12. Alday-Maldacena duality and AdS Plateau problem

    OpenAIRE

    Morozov, A.

    2008-01-01

    A short summary of approximate approach to the study of minimal surfaces in AdS, based on solving Nambu-Goto equations iteratively. Today, after partial denunciation of the BDS conjecture, this looks like the only constructive approach to understanding the ways of its possible modification and thus to saving the Alday-Maldacena duality. Numerous open technical problems are explicitly formulated throughout the text.

  13. SELF-MEDICATION AMONG DENTAL UNDERGRADUATE STUDENTS: A GROWING CONCERN

    OpenAIRE

    Suruchi Aditya

    2013-01-01

    Background: Self-medication is an important component of self-care. Though it is widely practiced globally, very few studies have evaluated its pattern and prevalence in dental students.Aim: The study was conducted to compare pattern of self-medication practices between junior and senior dental undergraduate students.Methods: This was a cross-sectional, anonymous, descriptive study with a six month illness recall that evaluated two groups of dental students- Group I: second year BDS students...

  14. Surveying Nepal’s Sexual and Gender Minorities: An Inclusive Approach

    OpenAIRE

    Knight, Kyle

    2014-01-01

    In a recent survey of sexual and gender minorities in Nepal over 60 percent of respondents reported experiencing at least one incident of abuse or discrimination, and over one-third reported discrimination or abuse in three or more public settings. The research methodology and study was implemented through the Williams Institute and the Blue Diamond Society (BDS). The survey utilized Nepal’s inclusion of a third gender category in its national census, the first such attempt in the wo...

  15. Evaluation of immunogenicity and reactogenicity of recombinant DNA hepatitis B vaccine produced in India

    OpenAIRE

    Hussain, Zahid; Ali, Syed S.; Husain, Syed A.; Raish, Mohammad; Sharma, Deepika R; Kar, Premashis

    2005-01-01

    AIM: (1) To gain information on immune responses to an accelerated schedule of 0, 1, and 2 mo in paramedical staff and BDS students who are at an increased risk of getting hepatitis B infection and come under high risk groups. (2) To assess the efficacy and safety of Enivac-HB in different age groups, using genetically modified yeast strain Pichia pastoris, a new recombinant hepatitis B vaccine developed and manufactured in India.

  16. 1,25-Dihydroxyvitamin-D3 Induces Avian β-Defensin Gene Expression in Chickens.

    Directory of Open Access Journals (Sweden)

    Long Zhang

    Full Text Available Host defense peptides (HDPs play a critical role in innate immunity. Specific modulation of endogenous HDP synthesis by dietary compounds has been regarded as a novel approach to boost immunity and disease resistance in animal production. 1,25-dihydroxy vitamin D3 (1,25D3 is well known as a powerful HDP inducer in humans, but limited information about the effect of 1,25D3 on HDPs in poultry is available. Here, we sought to examine whether 1,25D3 could stimulate avian β-defensin (AvBD expression in chickens. We used chicken embryo intestinal epithelial cells (CEIEPCs and peripheral blood mononuclear cells (PBMCs to study the effect of 1,25D3 on the expression of AvBDs. We observed that 1,25D3 is able to up-regulate the expression of several AvBDs in CEIEPCs and PBMCs, whereas it increased the amounts of AvBD4 mRNA in CEIEPCs only in the presence of lipopolysaccharide (LPS. On the other hand, LPS treatment not only inhibited the expression of CYP24A1 but also altered the expression pattern of VDR in CEIEPCs. Furthermore, AvBDs were not directly regulated by 1,25D3, as cycloheximide completely blocked 1,25D3-induced expression of AvBDs. Our observations suggest that 1,25D3 is capable of inducing AvBD gene expression and is a potential antibiotic alternative through augmentation of host innate immunity as well as disease control in chickens.

  17. Charm and charmonium-like spectroscopy in B decays in Belle

    OpenAIRE

    Aushev, T.

    2009-01-01

    We report measurements of the branching fractions for the decays B->D_s1(2536)+ anti-D(*), where anti-D(*) is anti-D0, D- or D*-, and study of B->X(3872) K with X(3872) decaying to D*0 anti-D0 using a sample of 657 million B anti-B pairs recorded at the Upsilon(4S) resonance with the Belle detector at the KEKB asymmetric-energy e+e- collider.

  18. Simultaneous determination of related substances of oxytetracycline in pharmaceutical semi-solid form by HPLC method

    OpenAIRE

    Violeta Giugiu

    2013-01-01

    Simultaneous determination of oxytetracycline, 4-epioxytetracycline, alpha-apooxytetracycline, tetracycline, beta-apooxytetracycline on C18 columns has been accomplished using a high performance liquid chromatographic method with UV detection. Separation was achieved on a Hypersil BDS RP-C18 column with a mobile phase consisted of acetonitrile-methanol-80 mM dipotassium phosphate pH 7,5 at a flow rate of 0,7 mL min-1. Absorbance measurements were held at 254 nm.

  19. DOES INCREASING DENTAL EDUCATION IMPROVE THE ORAL HYGIENE STATUS OF DENTAL STUDENTS?

    OpenAIRE

    Purnima V.; Thilagarani; Pramod; Vidyesh Durga; Nitin; Ravishankar; Anil; Amit

    2015-01-01

    OBJECTIVES: The purpose of this study was to assess the impact of increased knowledge acquired by the dental student in preventive aspects of dental education during his curriculum on his own health attitude, oral hygiene and gingival status. METHODS: A total of 240 students pursuing the undergraduate course (B.D.S) at t he New Horizon Dental College and Research Institute, Bilaspur (Chhattisgarh) were recruited for the study and divided into 4 groups based on the ...

  20. Development of RP-HPLC for analysis of human insulin

    OpenAIRE

    Rajan D; Gowda K; Mandal U; Ganesan.M; Bose A; Sarkar A; Pal T

    2006-01-01

    The objective of the present work is to develop a simple and sensitive method for analysis of human insulin injection by using reverse-phase high performance liquid chromatography technique. A reverse-phase high performance liquid chromatography method with UV-detection at room temperature has been developed for the analysis of insulin from formulation. Hypersil BDS C-18 was used as stationary phase, and mobile phase consisted of 60 volume of 1 mmol sodium sulphate and 0.2% triethylami...

  1. Positron annihilation and relaxation dynamics from dielectric spectroscopy and nuclear magnetic resonance: Cis-trans-1,4-poly(butadiene)

    Science.gov (United States)

    Bartoš, J.; Šauša, O.; Schwartz, G. A.; Alegría, A.; Alberdi, J. M.; Arbe, A.; Krištiak, J.; Colmenero, J.

    2011-04-01

    We report a joint analysis of positron annihilation lifetime spectroscopy (PALS), dielectric spectroscopy (BDS), and nuclear magnetic resonance (NMR) on cis-trans-1,4-poly(butadiene) (c-t-1,4-PBD). Phenomenological analysis of the orthopositronium lifetime τ3 - T dependence by linear fitting reveals four characteristic PALS temperatures: T_{b1} ^G = 0{.63}T_g^{PALS}, T_g^{PALS}, T_{b1} ^L = 1.22T_g^{PALS}, and T_{b2} ^L = 1.52T_g^{PALS}. Slight bend effects in the glassy and supercooled liquid states are related to the fast or slow secondary β process, from neutron scattering, respectively, the latter being connected with the trans-isomers. In addition, the first bend effect in the supercooled liquid coincides with a deviation of the slow effective secondary βeff relaxation related to the cis-isomers from low-T Arrhenius behavior to non-Arrhenius one and correlates with the onset of the primary α process from BDS. The second plateau effect in the liquid state occurs when τ3 becomes commensurable with the structural relaxation time τα(Tb2). It is also approximately related to its crossover from non-Arrhenius to Arrhenius regime in the combined BDS and NMR data. Finally, the combined BDS and NMR structural relaxation data, when analyzed in terms of the two-order parameter (TOP) model, suggest the influence of solidlike domains on both the annihilation behavior and the local and segmental chain mobility in the supercooled liquid. All these findings indicate the influence of the dynamic heterogeneity in both the primary and secondary relaxations due to the cis-trans isomerism in c-t-1,4-PBD and their impact into the PALS response.

  2. Pattern of mRNA expression of β-defensins in basal cell carcinoma

    International Nuclear Information System (INIS)

    Although the human β-defensins hBDs today seem to have diverse functional activities in innate antimicrobial immunity, a few reports also indicated an altered expression of these antimicrobial peptides (AMPs) in tissues of cancers such as oral squamous cell carcinoma. The present work was aimed on the study of hBD gene expression in basal cell carcinoma (BCC) which is the most common cancer in humans. Twenty-two non-ulcerated BCCs (12 nodular type, 10 superficial type) have been analysed for the presence of hBD (1–3) mRNA by quantitative real-time RT-PCR. As controls, non-lesional skin specimens of BCC patients as well as samples of healthy subjects were assessed by RT-PCR. hBD-1 levels in healthy controls and non-lesional skin of BCC patients were significantly (P < 0.05) higher than the levels observed in tumour tissue. Moreover, BCCs showed significantly (P < 0.05) increased mRNA expression of hBD-2 as compared to controls. There was no significant (P > 0.05) difference between lesional mRNA levels for hBD-3 and those levels observed in controls. The mRNA expression of hBDs (1–3) found in nodular and superficial BCCs did not significantly (P > 0.05) differ. The gene expression patterns of hBD-1 and hBD-2 are for the first time shown to be significantly altered in non-ulcerated BCCs as compared to intra-individual and inter-individual controls, respectively. The present findings may indicate that beside the antimicrobial activity of AMPs, hBDs may also play a role in the pathogenesis of BCC. However, functional and immunohistological studies investigating hBDs in patients with BCC are needed to confirm our data

  3. Use of NTRIP for Optimizing the Decoding Algorithm for Real-Time Data Streams

    OpenAIRE

    Zhanke He; Wenda Tang; Xuhai Yang; Liming Wang; Jihua Liu

    2014-01-01

    As a network transmission protocol, Networked Transport of RTCM via Internet Protocol (NTRIP) is widely used in GPS and Global Orbiting Navigational Satellite System (GLONASS) Augmentation systems, such as Continuous Operational Reference System (CORS), Wide Area Augmentation System (WAAS) and Satellite Based Augmentation Systems (SBAS). With the deployment of BeiDou Navigation Satellite system(BDS) to serve the Asia-Pacific region, there are increasing needs for ground monitoring of the BeiD...

  4. Riconoscimento del profilo professionale del bibliotecario documentalista in sanità

    OpenAIRE

    Truccolo, Ivana; Vidale, Claudia; Falcetta, Anna Maria; Merighi, Roberta

    2006-01-01

    In Italy the reference institution for all librarians is AIB (Associazione Italiana Biblioteche), while AIDA, the Association for the Advanced Documentation, contributes to develop documentation diffusion and information science. The Ministry of Health also plays an important role in supporting the libraries of Biomedical Research Institutes (IRCCS). The BDS Association (Bibliotecari Documentalisti della Sanità) was founded in 2000 with the purpose of highlight the specific activities perf...

  5. On Chaotic Nature of the Emerging European Forex Markets

    OpenAIRE

    Anoop S. KUMAR; B Kamaiah

    2014-01-01

    This study attempts to analyze the presence deterministic chaos in the forex markets of select European countries namely Bulgaria, Croatia, Czech Republic, Hungary Poland, Romania, Russia, Slovakia and Slovenia. Monthly NEER data ranging from jan-1994 to Dec-2013 is used for the purpose of analysis. A two step methodology is employed where in the first step, non-linear dependence structure in the underlying time series is verified using BDS test. The results show that all the markets under st...

  6. Dealing with phraseology in business dictionaries: focus on dictionary functions – not phrases

    OpenAIRE

    Leroyer, Patrick

    2006-01-01

    The language of written business communication is characterised by the extensive use of phraseology, not only in terms of collocations and idiomatic expressions, but also of standard phrases in prototypical business genres. In any case, the phraseological information should be included in business dictionaries (in the following referred to as BDs) in accordance with the planned dictionary functions. Hence, the selection and presentation of the phraseological information should be decided by t...

  7. A homogeneous analysis of disks around brown dwarfs

    CERN Document Server

    Liu, Y; Bayo, A; Nielbock, M; Wang, H

    2015-01-01

    We re-analyzed the Herschel/PACS data of a sample of 55 brown dwarfs (BDs) and very low mass stars with spectral types ranging from M5.5 to L0. We investigated the dependence of disk structure on the mass of the central object in the substellar regime based on a homogeneous analysis of Herschel data from flux density measurements to spectral energy distribution (SED) modeling. A systematic comparison between the derived disk properties and those of sun-like stars shows that the disk flaring of BDs and very low mass stars is generally smaller than that of their higher mass counterparts, the disk mass is orders of magnitude lower than the typical value found in T Tauri stars, and the disk scale heights are comparable in both sun-like stars and BDs. We further divided our sample into an early-type brown dwarf (ETBD) group and a late-type brown dwarf (LTBD) group by using spectral type (=M8) as the border criterion. We systematically compared the modeling results from Bayesian analysis between these two groups, a...

  8. Long-term evolution of the inclined geosynchronous orbit in Beidou Navigation Satellite System

    Science.gov (United States)

    Tang, Jingshi; Hou, Xiyun; Liu, Lin

    2016-07-01

    China's Beidou Navigation Satellite System (BDS), unlike other navigation satellite systems, uses several inclined geosynchronous orbits (IGSO) to enhance the accuracy of regional or global navigation. In order to maintain a safe space environment in the vicinity of its operational orbit, it is necessary that the decommissioned satellites be well disposed of. Following up the study on the specific BDS IGSO satellites in the previous COSPAR Scientific Assembly, we now extend the study to understand the underlying dynamics and discuss the long-term evolution of such orbits from a more general perspective. In this paper, we first theoretically analyze the problem using simplified models of 1 and 2 degrees of freedoms (1-/2-dof). Then we extensively investigate the numerically propagated orbits for 200 and 1000 years, applying the results from these simplified models and seeking proper explanations for the underlying dynamics. We especially focus on the eccentricity evolution, which is a major concern regarding the collision hazard. We expect to understand the underlying dynamics governing the long-term evolution of BDS IGSO and gain helpful insight into future disposal strategies.

  9. The properties of brown dwarfs and low-mass hydrogen-burning stars formed by disc fragmentation

    CERN Document Server

    Stamatellos, Dimitris

    2008-01-01

    We suggest that a high proportion of brown dwarfs are formed by gravitational fragmentation of massive extended discs around Sun-like stars. Such discs should arise frequently, but should be observed infrequently, precisely because they fragment rapidly. By performing an ensemble of radiation-hydrodynamic simulations, we show that such discs fragment within a few thousand years, and produce mainlybrown dwarf (BDs) stars, but also planetary mass (PM) stars and very low-mass hydrogen-burning (HB) stars. Most of the the PM stars and BDs are ejected by mutual interactions. We analyse the statistical properties of these stars, and compare them with observations. After a few hundred thousand years the Sun-like primary is typically left with a close low-mass HB companion, and two much wider companions: a low-mass HB star and a BD star, or a BD-BD binary. There is a BD desert extending out to at least ~100 AU; this is because BDs tend to be formed further out than low-mass HB stars, and then they tend to be scattered...

  10. Self assembled hyaluronic acid nanoparticles as a potential carrier for targeting the inflamed intestinal mucosa.

    Science.gov (United States)

    Vafaei, Seyed Yaser; Esmaeili, Motahareh; Amini, Mohsen; Atyabi, Fatemeh; Ostad, Seyed Naser; Dinarvand, Rassoul

    2016-06-25

    To develop a nanoparticulate drug carrier for targeting of the inflamed intestinal mucosa, amphiphilic hyaluronic acid (HA) conjugates were synthesized, which could form self-assembled nanoparticles (NPs) in aqueous solution and budesonide (BDS) was loaded into the HANPs. Their particle sizes were in the range of 177 to 293nm with negative surface charge. The model of inflammatory CACO-2 cells was utilized to investigate the therapeutic potential of budesonide loaded HA nanocarriers. The highest expression of CD44 receptors was found on inflamed Caco-2 cells, as determined by flow cytometry. FITC-labeled HANPs revealed greater uptake in inflamed CACO-2 cells compared to untreated CACO-2 and CD44-negative cell lines, NIH3T3. BDS loaded HANPs displayed almost no toxicity indicating HANPs are excellent biocompatible nano-carriers. BDS loaded HANPs demonstrated higher anti-inflammatory effect on IL-8 and TNF-α secretion in inflamed cell model compared to the same dose of free drug. These results revealed the promising potential of HA nanoparticles as a targeted drug delivery system for IBD treatment. PMID:27083829

  11. New Brown Dwarfs and an Updated Initial Mass Function in Taurus

    CERN Document Server

    Luhman, K L

    2004-01-01

    I have performed a search for young low-mass stars and brown dwarfs (BDs) in 2 regions encompassing a total area of 4 deg^2 in the Taurus star-forming region, discovering 15 new members of Taurus. In addition, I present 7 new members outside of these areas from the initial stage of a survey of all of Taurus. These 22 objects exhibit spectral types of M4.5-M9.25 and masses of 0.3-0.015 M_sun according to the theoretical evolutionary models of Baraffe and Chabrier, 7 of which are likely to be BDs. Emission in H(alpha), He I, Ca II, [O I], and [S II] and excess emission in optical and near-IR bands among some of these objects suggest the presence of accretion, outflows, and circumstellar disks. The results from the 4 deg^2 survey have been combined with previous studies of Taurus to arrive at an IMF for a total area of 12.4 deg^2. As in the previous IMFs for Taurus, the updated IMF peaks at a higher mass (0.8 M_sun) than the mass functions in IC 348 and Orion (0.1-0.2 M_sun). Meanwhile, the deficit of BDs in Tau...

  12. Time evolution of ground motion-dependent depolarisation at linear colliders

    CERN Document Server

    Bailey, I; Beckmann, M; Hartin, A; Helebrant, C; Kaefer, D; List, J; Moortgat-Pick, G

    2011-01-01

    Future linear colliders plan to collide polarised beams and the planned physics reach requires knowledge of the state of polarisation as precisely as possible. The polarised beams can undergo depolarisation due to various mechanisms. In order to quantify the uncertainty due to depolarisation, spin tracking simulations in the International Linear Collider (ILC) Beam Delivery System (BDS) and at the Interaction Point (IP) have been performed. Spin tracking in the BDS was achieved using the BMAD subroutine library, and the CAIN program was used to do spin tracking through the beam-beam collision. Assuming initially aligned beamline elements in the BDS, a ground motion model was applied to obtain realistic random misalignments over various time scales. Depolarisation at the level of 0.1% occurs within a day of ground motion at a noisy site. Depolarisation at the IP also exceeds 0.1% for the nominal parameter sets for both the ILC and for the Compact Linear Collider (CLIC). Theoretical work is underway to include ...

  13. Rotational studies in the Orion Nebula Cluster: from solar mass stars to brown dwarfs

    CERN Document Server

    Rodriguez-Ledesma, Maria Victoria; Eislöffel, Jochen

    2009-01-01

    Rotational studies at a variety of ages and masses are important for constraining the angular momentum evolution of young stellar objects (YSO). Of particular interest are the very low mass (VLM) stars and brown dwarfs (BDs), because of the significant lack of known rotational periods in that mass range. We provide for the first time information on rotational periods for a large sample of young VLM stars and BDs. This extensive rotational period study in the 1 Myr old Orion Nebula Cluster (ONC) is based on a deep photometric monitoring campaign using the Wide Field Imager (WFI) camera on the ESO/MPG 2.2m telescope on La Silla, Chile. Accurate I-band photometry of 2908 stars was obtained, extending three magnitudes deeper than previous studies in the ONC. We found 487 periodic variables with estimated masses between 0.5 Msun and 0.015 Msun, 124 of which are BD candidates. This is by far the most extensive and complete rotational period data set for young VLM stars and BDs. In addition, 808 objects show non-per...

  14. Multi-wavelength Study of Transition Region Penumbral Subarcsecond Bright Dots Using IRIS and NST

    CERN Document Server

    Deng, Na; Tian, Hui; Kleint, Lucia; Liu, Chang; Xu, Yan; Wang, Haimin

    2016-01-01

    Using high-resolution transition region (TR) observations taken by the Interface Region Imaging Spectrograph (IRIS) mission, Tian et al. (2014b) revealed numerous short-lived subarcsecond bright dots (BDs) above sunspots (mostly located in the penumbrae), which indicate yet unexplained small-scale energy releases. Moreover, whether these subarcsecond TR brightenings have any signature in the lower atmosphere and how they are formed are still not fully resolved. This paper presents a multi-wavelength study of the TR penumbral BDs using a coordinated observation of a near disk-center sunspot with IRIS and the 1.6 m New Solar Telescope (NST) at the Big Bear Solar Observatory. NST provides high-resolution chromospheric and photospheric observations with narrow-band H-alpha imaging spectroscopy and broad-band TiO images, respectively, complementary to IRIS TR observations. A total of 2692 TR penumbral BDs are identified from a 37-minute time series of IRIS 1400 A slitjaw images. Their locations tend to be associat...

  15. Dealing with phraseology in business dictionaries: focus on dictionary functions – not phrases

    Directory of Open Access Journals (Sweden)

    Leroyer, Patrick

    2006-01-01

    Full Text Available The language of written business communication is characterised by the extensive use of phraseology, not only in terms of collocations and idiomatic expressions, but also of standard phrases in prototypical business genres. In any case, the phraseological information should be included in business dictionaries (in the following referred to as BDs in accordance with the planned dictionary functions. Hence, the selection and presentation of the phraseological information should be decided by the lexicographer on the basis of the user needs alone and not on the recommendations of the phraseological literature about lexicographical practice. In this paper, I will firstly explain why lexicography and phraseology, although closely associated in a large number of studies, are quite different disciplines, and how their shared interest for dictionary practice in general is based on radically different views. I will then discuss the dictionary functions of BDs and focus on a number of concepts featuring extensive phraseological solutions to show and argue that dealing with phraseology in BDs should always keep focus on dictionary functions.

  16. Effect of nutrient nitrogen on laccase production, its isozyme pattern and effluent decolorization by the fungus NIOCC No. 2a, isolated from mangrove wood

    Digital Repository Service at National Institute of Oceanography (India)

    DeSouza-Ticlo, D.; Verma, A.K.; Mathew, M.; Raghukumar, C.

    the 12 day-old cultures grown in different nitrogen sources as well as those supplemented with effluent were concentrated by ultra filtration with nanosep centriguge tubes (Pall Gellman, USA) having 3 kDa cut-off membrane at 5,000 rpm (4°C). After... of NIOCC # 2a in media with different N sources and effluents Fungal growth was best in the presence of glutamic acid as the nitrogen (N) source. When supplemented with black liquor (BL), the fungus showed enhanced growth in all the nitrogen...

  17. A straightforward methodology for designing continuous monoclonal antibody capture multi-column chromatography processes.

    Science.gov (United States)

    Gjoka, Xhorxhi; Rogler, Karl; Martino, Richard Alexander; Gantier, Rene; Schofield, Mark

    2015-10-16

    A simple process development strategy for continuous capture multi-column chromatography (MCC) is described. The approach involves a few single column breakthrough experiments, based on several simplifying observations that enable users to rapidly convert batch processes into well-designed multi-column processes. The method was validated using a BioSMB(®) (Pall Life Sciences) lab scale multi-column system and a mAb capture process employing Protein A resin. The approach enables users to optimize MCC processes based on their internal preferences and constraints without requiring any mathematical modeling expertise.

  18. A new species of Astragalus (Fabaceae from west coast of Baikal Lake (Irkutsk Oblast

    Directory of Open Access Journals (Sweden)

    N. V. Stepantsova

    2015-05-01

    Full Text Available A new species, Astragalus rytyensis Stepantsova (Fabaceae, growing on the west coast of the lake Baikal, is described. Morphological differences from related taxa – A. versicolor Pall., A. austrosibiricus Schischk., and A. inopinatus Boriss., are discussed and uncertain position of the new species in the system of the genus is emphasized which is intermediate between subg. Phaca (L. Bunge sect. Hemiphaca Bunge and subg. Cercidothrix Bunge sect. Onobrychium Bunge. Ecological and phonological features of A. rytyensis are reported and chromosome numbers of the new (2n = 6x = 48 and related species are counted.

  19. 铁线莲属威灵仙组修订(续)%A revision of Clematis sect. Clematis (Ranunculaceae) (Continued)

    Institute of Scientific and Technical Information of China (English)

    王文采

    2003-01-01

    @@ Subsection 4. Angustifoliae Tamura in Sci. Rep. Osaka Univ. 4: 55. 1955 et 16 (2): 33. 1967; M. C. Chang in Fl. Reip. Pop. Sin. 28: 156. 1980. --Sect. Flammula DC. Subsect. Angustifoliae (Tamura) Tamura in Acta Phytotax. Geobot. 16: 81. 1956 et 38: 43. 1987; M. Johnson, Klematis 603. 1997; Grey_Wils., Clematis 113. 2000. -- Sect. Angustifoliae (Tamura) Serov in Bot. Zhurn. 73 (12): 1740. 1988; Tamura in Heipko, Engler's Nat. Pflanzenfam., ed. 2, 17a (4): 383. 1995. Type: C. Hexapetala Pall.

  20. Application of fine absolute rated filters to PWR CVCS and radwaste filter duties

    International Nuclear Information System (INIS)

    Filters for PWR systems have generally been specified in terms of nominal removal ratings. Products supplied by different manufacturers against these specifications vary considerably in removal efficiency and service life. The paper describes the method used by Pall Corporation for reliable, reproducible assessment of filter performance and determination of absolute filtration ratings. The old nominal specifications are shown to be too coarse for effective removal of particle borne activity. The introduction into service of new absolute rated fine filter media with positive zeta potential is described. (author)

  1. Optimized production technology (OPT), theory of constraints (TOC) og den dertil hørende økonomistyringstankegang 'Throughput Accounting (TPA)'

    DEFF Research Database (Denmark)

    Nielsen, Steen; Hansen, Tom Albæk

    2005-01-01

    som Just-In-Time (JIT) og Life-Cycle-Costing (LCC) vil fremover kunne give inspiration til nye måder at anskue økonomistyringen på. TOC, JIT og LCC kombineres ofte, både i relation til de mere operative beslutninger, men også i relation til virksomhedens strategiledelse. Ideen er, at også de...... danske lønsomhedsmodel, udviklet af Palle Hansen og Zakken Worre, hvor fokus også er på dækningsbidrag per knap faktor. Hvor JIT er tæt knyttet til økonomistyringstankegangen - backflush accounting - er OPT og TOC knyttet til TPA....

  2. Drip Irrigation Conditions within the Scope of Mixed Deposited Salt Resistant to Salt Grass and the Changing Trend of Salt%滴灌条件下积盐范围内混种耐盐草及盐分变化趋势的研究

    Institute of Scientific and Technical Information of China (English)

    穆哈西; 赛尔江·乌尔曼别克

    2011-01-01

    以pH=7.9的水作为灌溉水源,土壤含水率、土壤密度及滴头流量不同的条件下,对土壤湿润体的变化过程进行试验,确定湿润峰及积盐范围,在积盐范围内混种盐角草和猪毛菜。测定土壤酸碱度及易溶盐离子总量的减少量,并积盐范围内混种的盐角草和猪毛菜与普通土壤中栽培的盐角草和猪毛菜的盐含量进行对比。结果表明,盐角草吸走部分Na+、Cl-离子,猪毛菜吸走土壤中的CO32-、SO42-离子,积盐范围内土深20cm处总含盐量降低了0.26g/kg。%pH=7.9 to the water as irrigation water,soil moisture,soil bulk density and drops under the condition of different head flow,moist soil body of the change process,determine the wet peak and deposited salt,salt in product range within the scope of mixed salt grass and Salsola collina pall.Angle Measuring soil ph and soluble salt ions decrease of total amount deposited salt,and within the scope of mixed salt grass and Salsola collina pall.and Angle of the cultivation common soil salt Angle grass and Salsola collina pall the salt content of the dishes were compared.The results show that,salt Angle grass attract part,making Na+ and CI-ions,Salsola collina pall salt inhibit drain on the soil of CO2-3 and SO2-4 ions,deposited salt-within 20 cm deep soil in salt content at reduced total 0.26 g/kg.

  3. Surface selective membranes for carbon dioxide separation

    Energy Technology Data Exchange (ETDEWEB)

    Luebke, D.R.; Pennline, H.W.; Myers, C.R.

    2005-09-01

    In this study, hybrid membranes have been developed for the selective separation of CO2 from mixtures containing H2. Beginning with commercially available Pall alumina membrane tubes with nominal pore diameter of 5 nm, hybrids were produced by silation with a variety of functionalities designed to facilitate the selective adsorption of CO2 onto the pore surface. The goal is to produce a membrane which can harness the power of surface diffusion to give the selectivity of polymer membranes with the permeance of inorganic membranes.

  4. 威灵仙临床新用

    Institute of Scientific and Technical Information of China (English)

    胡烈

    2001-01-01

    @@ 威灵仙为毛茛科植物威灵仙Clematis Chinensis Osbeck.棉团铁线莲C. herapetala pall.东北铁线莲C.等的根及根茎.又名:铁脚威灵仙、灵仙、黑脚威灵仙.喜生于山坡、沟边、路旁草丛中.主产于江苏、安徽、浙江等地.秋季采挖,去净茎叶,冼净泥土,晒干,或切成段晒于.生用或酒炒后用.

  5. О НОВЫХ И НАИБОЛЕЕ РЕДКИХ ВИДАХ ТАМБОВСКОЙФЛОРЫ. СООБЩЕНИЕ 4

    OpenAIRE

    Соколов, Александр; Соколова, Людмила

    2014-01-01

    В работе сообщаются сведения о новых (Astragalus pubiflorus (Pall.)) DC., Veronica persica Poir., Dipsacus strigosus Willd. ex Roem. et Schult.) и наиболее редких (Ephedra distachya L., Stipa lessingiana Trin. et Rupr., S. pulcherrima C. Koch, Rhynchospora alba (L.) Vahl, Carex humilis Leysser, Veratrum nigrum L., Anthericum ramosum L., Lilium martagon L., Ceratocarpus arenarius L., Arenaria procera Spreng., Silene sibirica (L.) Pers., Actaea spicata L., Aconitum anthora L., Clematis integrif...

  6. Are female daycare workers at greater risk of cytomegalovirus infection? A secondary data analysis of CMV seroprevalence between 2010 and 2013 in Hamburg, Germany

    Directory of Open Access Journals (Sweden)

    Stranzinger, Johanna

    2016-04-01

    Full Text Available Background: Close contact with asymptomatic children younger than three years is a risk factor for a primary cytomegalovirus (CMV infection. In pregnant women, such primary infection increases the risk of CMV-induced feto- or embryopathy. Daycare providers have therefore implemented working restrictions for pregnant daycare workers (DCWs in accordance with legislation and guidelines for maternity protection. However, little is known about the infection risk for DCWs. We therefore compared the prevalence of CMV antibodies of pregnant DCWs to that of female blood donors (BDs.Method: In a secondary data analysis, the prevalence of anti-CMV IgG among pregnant DCWs (N=509 in daycare centers (DCCs was compared to the prevalence of female first-time BDs (N=14,358 from the greater region of Hamburg, Germany. Data collection took place between 2010 and 2013. The influence of other risk factors such as age, pregnancies and place of residence was evaluated using logistic regression models. Results: The prevalence of CMV antibodies in pregnant DCWs was higher than in female BDs (54.6 vs 41.5%; OR 1.6; 95%CI 1.3–1.9. The subgroup of BDs who had given birth to at least one child and who lived in the city of Hamburg (N=2,591 had a prevalence of CMV antibodies similar to the prevalence in pregnant DCWs (53.9 vs 54.6%; OR 0.9; 95%CI 0.8–1.2. Age, pregnancy history and living in the center of Hamburg were risk factors for CMV infections.Conclusion: The comparison of pregnant DCWs to the best-matching subgroup of female first-time BDs with past pregnancies and living in the city of Hamburg does not indicate an elevated risk of CMV infection among DCWs. However, as two secondary data sets from convenience samples were used, a more detailed investigation of the risk factors other than place of residence, age and maternity was not possible. Therefore, the CMV infection risk in DCWs should be further studied by taking into consideration the potential preventive

  7. THE BIOCATALYTIC DESULFURIZATION PROJECT

    Energy Technology Data Exchange (ETDEWEB)

    Scott Collins; David Nunn

    2003-10-01

    The analysis of Petro Star diesel sulfur species is complete and a report is attached. Further analytical efforts will concentrate on characterization of diesel fuel, hydrodesulfurized to varying degrees, in order to determine sulfur species that may be problematic to hydrogen treatment and represent potential target substrates for biodesulfurization in a combined HDS-BDS process. Quotes have been received and are being considered for the partial treatment of Petro Star Inc. marine diesel fuel. Direction of research is changing slightly; economic analysis of the hyphenated--BDSHDS, BDS-CED--has shown the highest probability of success to be with a BDS-HDS process where the biodesulfurization precedes hydrodesulfurization. Thus, the microorganisms will be tailored to focus on those compounds that tend to be recalcitrant to hydrodesulfurization and decrease the severity of the hydrodesulfurization step. A separate, detailed justification for this change is being prepared. Research activities have continued in the characterization of the desulfurization enzymes from multiple sources. Genes for all DszA, -B, -C and -D enzymes (and homologs) have been cloned and expressed. Activity determinations, on a variety of substituted benzothiophene and dibenzothiophene substrates, have been carried out and continue. In addition, chemical synthesis efforts have been carried out to generate additional substrates for analytical standards and activity determinations. The generation of a GSSM mutant library of the ''Rhodococcus IGTS8 dszA'' gene has been completed and development of protocols for a high throughput screen to expand substrate specificity are nearing completion. In an effort to obtain improved hosts as biocatalyst, one hundred-thirty ''Rhodococcus'' and related strains are being evaluated for growth characteristics and other criteria deemed important for an optimal biocatalyst strain. We have also begun an effort to generate

  8. Induction and Proliferation Conditions of Onion(Allium cepa L.) Embryogenic Callus%洋葱胚性愈伤组织的诱导及增殖条件的研究

    Institute of Scientific and Technical Information of China (English)

    代月; 吴雄; 朴炫春; 霍雨猛; 缪军; 廉美兰

    2012-01-01

    [目的]探讨洋葱离体培养的最佳条件,为建立其高频再生体系及转基因研究奠定技术基础.[方法]以洋葱(Allium cepa L.)种子为外植体,对洋葱愈伤组织的诱导、胚性愈伤组织获得及增殖的培养条件进行了初步研究.[结果]不同培养基种类对愈伤组织的诱导有影响,BDS优于MS和B5培养基;当培养基中2,4-D浓度为0.5 mg,/L时种子出愈率最高;适当降低生长素浓度,添加分裂素BA能够促进胚性愈伤组织的发生,且无分化现象产生,胚性愈伤组织诱导最佳培养基为BDS+2,4-D 0.25 mg/L+BA 2.0 mg/L,增殖最佳培养基为BDS+2,4-D O.25 mg/L+BA 1.0 mg/L.[结论]该试验建立的基因转化受体系统为洋葱基因转化奠定了良好基础.%[Objective] To explore the best conditions for the in vitro culture of onion, so as to lay technical foundation for its trangenic research and the establishment of high frequency regeneration system. [ Method] With the onion seeds as explants, the induction and proliferation conditions of onion (Alliiim r.epa L. ) callus and embryogenic callus were preliminarily studied. [ Result] The types of callus produced certain impact on the induction of callus, BDS was better than MS and B5; the callus rate was the highest at the concentrations of 0. 5 mg/L 2,4-D; the appropriate reduction of auxin concentration and addition of cytokinin BA could promote the induction of enbryogenic callus without differentiation, the best embryogenic callus induction medium was BDS +2,4-D 0. 25 mg/L + BA 2.0 mg/L and the best proliferation medium was BDS + 2,4-D 0.25 mg/L + BA 1.0 mg/L. [Conclusion] Hie transgenic receptor system established in this experiment lays good foundation for the genetic transformation of onion.

  9. Specificity of germination of heteromorphic seeds in four annuals (Salsola L.) at different temperatures in the Junggar basin

    International Nuclear Information System (INIS)

    Salsola L. is a large genus of arid desert plants that are primarily distributed in the Junggar Basin, China. We analysed their ability to adapt to arid habitats by comparing differences in germination characteristics of the species and populations of Salsola affinis C. A. Mey, Salsola korshinskyi Drob., Salsola brachiata Pall. and Salsola nitraria Pall. We classified the 4 species into four types (A, B, C and D) according to seed wing and seed size, and the heteromorphic seeds were incubatedunder different temperature regimes (0/10 degree C, 5/15 degree C, 10/25 degree C and 20/35 degree C). The 4 species had the highest germination rates and germination potential at 0/1 C. Germination rates and potential decreased with increasing temperature. However, the change range of the germination rate among the four species was different. Type A and B seeds of S. affinis, S. nitraria and S. korshinskyi were dominant at all temperatures and decreased with increasing temperature. The germination rate of type C seeds was between that of type A, B and D seeds. D-type seeds had the lowest germination rate and the lowest germination potential under the four temperature regimes among the four species but the differences were not significant. The germination rates of the four types of S. brachiata seeds did not significantly change with temperature. These results suggest that Salsola spp. can germinate continuously from spring to autumn to adapt to moisture fluctuations in the desert. (author)

  10. Evaluation Of Alternative Filter Media For The Rotary Microfilter, Phase 2

    International Nuclear Information System (INIS)

    Testing was conducted at the Savannah River National Laboratory (SRNL) to investigate filter membrane performance in an effort to increase rotary microfilter (RMF) throughput. Membranes were tested in the SpinTek Filtration, Inc. Static Test Cell (STC), which permitted quick and easy testing of several different membranes. Testing consisted of 100 hours tests with two different slurry feeds, based on recommendations from the phase 1 testing. One feed contained Monosodium Titanate (MST) solids in a simulated salt solution. The other feed contained simulated sludge batch 6 (SB6) solids in a simulated salt solution. Five membranes were tested, one each from filter manufactures Pall and Porvair and three from the Oak Ridge National Laboratory (ORNL). The membrane from Pall is the current membrane used on the latest generation RMF. The Porvair membrane performed well in previous STC tests as well as one of the ORNL membranes. The other two membranes from ORNL were recently developed and not available for the previous STC test. The results indicate that the Porvair filter performed best with the MST slurry and the ORNL SVB6-1B filter performed best with the SB6 slurry. Difficulty was encountered with the ORNL filters due to their dimensional thickness, which was greater than the recommended filter thickness for the STC. The STC equipment was modified to complete the testing of the ORNL filters.

  11. Pyrolysis Oil Stabilization: Hot-Gas Filtration; Cooperative Research and Development Final Report, CRADA Number CRD-09-333

    Energy Technology Data Exchange (ETDEWEB)

    Baldwin, R.

    2012-07-01

    The hypothesis that was tested in this task was that separation of char, with its associated mineral matter from pyrolysis vapors before condensation, will lead to improved oil quality and stability with respect to storage and transportation. The metric used to evaluate stability in this case was a 10-fold reduction in the rate of increase of viscosity as determined by ASTM D445 (the accelerated aging test). The primary unit operation that was investigated for this purpose was hot-gas filtration. A custom-built heated candle filter system was fabricated by the Pall Corporation and furnished to NREL for this test campaign. This system consisted of a candle filter element in a containment vessel surrounded by heating elements on the external surface of the vessel. The filter element and housing were interfaced to NREL?s existing 0.5 MTD pyrolysis Process Development Unit (PDU). For these tests the pyrolysis reactor of the PDU was operated in the entrained-flow mode. The HGF test stand was installed on a slipstream from the PDU so that both hot-gas filtered oil and bio-oil that was not hot-gas filtered could be collected for purposes of comparison. Two filter elements from Pall were tested: (1) porous stainless steel (PSS) sintered metal powder; (2) sintered ceramic powder. An extremely sophisticated bio-oil condensation and collection system was designed and fabricated at NREL and interfaced to the filter unit.

  12. Paeonol attenuates inflammation-mediated neurotoxicity and microglial activation

    Institute of Scientific and Technical Information of China (English)

    Kyong Nyon Nam; Byung-Cheol Woo; Sang-Kwan Moon; Seong-Uk Park; Joo-young Park; Jae-Woong Hwang; Hyung-Sup Bae; Chang-Nam Ko; Eunjoo Hwang Lee

    2013-01-01

    Chronic activation of microglial cells endangers neuronal survival through the release of various proinflammatory and neurotoxic factors. The root of Paeonia lactiflora Pall has been considered useful for the treatment of various disorders in traditional oriental medicine. Paeonol, found in the root of Paeonia lactiflora Pall, has a wide range of pharmacological functions, including anti-oxidative, anti-inflammatory and neuroprotective activities. The objective of this study was to examine the efficacy of paeonol in the repression of inflammation-induced neurotoxicity and microglial cell activation. Organotypic hippocampal slice cultures and primary microglial cells from rat brain were stimulated with bacterial lipopolysaccharide. Paeonol pretreatment was performed for 30 minutes prior to lipopolysaccharide addition. Cell viability and nitrite (the production of nitric oxide), tumor necrosis factor-alpha and interleukin-1beta products were measured after lipopolysaccharide treatment. In organotypic hippocampal slice cultures, paeonol blocked lipopolysaccharide-related hippocampal cell death and inhibited the release of nitrite and interleukin-1beta. Paeonol was effective in inhibiting nitric oxide release from primary microglial cells. It also reduced the lipopolysaccharide-stimulated release of tumor necrosis factor-alpha and interleukin-1β from microglial cells. Paeonol possesses neuroprotective activity in a model of inflammation-induced neurotoxicity and reduces the release of neurotoxic and proinflammatory factors in activated microglial cells.

  13. Antimicrobial and antiradical activity of extracts obtained from leaves of three species of the genus pyrus.

    Science.gov (United States)

    Zbigniew, Sroka; Beata, Żbikowska; Kamil, Janicki; Roman, Franiczek; Barbara, Krzyżanowska; Andrzej, Dryś

    2014-08-01

    In this study, extracts were obtained from leaves of Pyrus communis L., Pyrus elaeagrifolia Pall., and Pyrus pyrifolia (Bum.) Nak. These extracts were tested for antiradical and antibacterial activity, as well as for the amount of total phenolic compounds, hydroquinone and arbutin. The antiradical activity was measured using 2,2-diphenyl-1-picrylhydrazyl radical and antibacterial activity with the disk diffusion method. The amount of phenolic compounds was determined using Folin Ciocalteu's phenol reagent, but the amount of hydroquinone and arbutin was measured with high performance liquid chromatography. The strongest antiradical activity was observed for ethyl acetate extract from leaves of P. communis L., and the lowest for the poorly soluble fraction (precipitate) from leaves of P. elaeagrifolia Pall. The highest number of antiradical units per gram of raw materials was noted for leaves of P. communis. The strongest antibacterial activity was measured for ethyl acetate extracts. The calculation of Spearman rank correlation coefficients indicated the existence of a positive correlation between contents of hydroquinone in extracts and their antibacterial activity for almost all investigated bacterial strains. The strains of fungi such as Candida albicans and Saccharomyces cerevisiae were completely resistant to the action of extracts. PMID:24621262

  14. Age, puberty, body dissatisfaction, and physical activity decline in adolescents. Results of the German Health Interview and Examination Survey (KiGGS

    Directory of Open Access Journals (Sweden)

    Finne Emily

    2011-10-01

    Full Text Available Abstract Background Physical activity (PA shows a marked decline during adolescence. Some studies have pointed to pubertal status or timing as possible PA determinants in this age group. Furthermore, it was supposed that the impact of pubertal changes on PA might be mediated by psychological variables like body dissatisfaction (BDS. Methods The 11- to 17-year-old subsample of the German Health Interview and Examination Survey (KiGGS was used (n = 6 813; 51.3% male, response rate = 66.6%. Through sex-specific sequential multinomial logistic regressions we analysed the univariate and independent associations of chronological age, absolute pubertal status, relative pubertal timing, and BDS with the frequency of PA. Results Chronological age showed a significantly negative association with PA in both sexes, independent of puberty. The odds of inactivity in contrast to nearly daily PA increased about 70% in boys and 35% in girls for each year of age, respectively. Adjusted for age and other possible confounders, inactivity was significantly less likely for boys in late pubertal stages (OR = 0.27, 95% CI = 0.09-0.78. The risk of inactivity was more than doubled in boys maturing earlier than peers in terms of relative pubertal timing (OR = 2.20, 95% CI = 1.36-3.56. No clear significant puberty effects were found in girls, but the inactivity was more likely for those with irregular menstruation (OR = 1.71, 95% CI = 1.06-2.75. BDS also contributed to the prediction of PA in both sexes. It partially mediated puberty effects in boys but not in girls. Conclusions Overall, chronological age was a far more important predictor of PA in German adolescents than absolute pubertal status or relative pubertal timing. Further possible explanatory variables like sociocultural influences, social support or increasing time requirements for education should be analysed in conjunction with chronological age in future studies.

  15. Energy storage properties in Ba{sub 0.4}Sr{sub 0.6}TiO{sub 3} ceramics with addition of semi-conductive BaO–B{sub 2}O{sub 3}–SiO{sub 2}–Na{sub 2}CO{sub 3}–K{sub 2}CO{sub 3} glass

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Tong; Jin, Li, E-mail: ljin@mail.xjtu.edu.cn; Shu, Longlong; Hu, Qingyuan; Wei, Xiaoyong, E-mail: wdy@mail.xjtu.edu.cn

    2014-12-25

    Highlights: • Semiconductive BaO–B{sub 2}O{sub 3}–SiO{sub 2}–Na{sub 2}CO{sub 3}–K{sub 2}CO{sub 3} glass was added to Ba{sub 0.4}Sr{sub 0.6}TiO{sub 3} ceramic. • Sintering temperature was lowered about 150 °C with a high relative density (∼98%). • Dielectric constant of BST glass ceramics decrease with increasing Na{sub 2}CO{sub 3} content. • BDS and energy density of BST glass ceramics increase with increasing Na{sub 2}CO{sub 3} content. - Abstract: Semi-conductive BaO–B{sub 2}O{sub 3}–SiO{sub 2}–Na{sub 2}CO{sub 3}–K{sub 2}CO{sub 3} glass additives were added to Ba{sub 0.4}Sr{sub 0.6}TiO{sub 3} (BST) ceramics to investigate its influences on the microstructure, dielectric properties, breakdown strength (BDS), and energy storage density. The sintering temperatures were lowered about 150 °C with a high relative density (∼98%). X-ray diffraction patterns of all BST glass ceramics suggest perovskite structures without any detectable secondary phase. Room temperature dielectric constant of BST glass ceramics decreases with increasing Na{sub 2}CO{sub 3} content. BDS and energy storage density of BST glass ceramics increase with increasing Na{sub 2}CO{sub 3} content, and reach their maxima of 280 kV/cm and 0.72 J/cm{sup 3} at the highest Na{sup +} and K{sup +} content. These results suggest that the BST glass ceramics could find their potential applications in energy storage capacitor devices.

  16. Evaluation of small wind turbines in distributed arrangement as sustainable wind energy option for Barbados

    International Nuclear Information System (INIS)

    The island of Barbados is 99% dependent on fossil fuel imports to satisfy its energy needs, which is unsustainable. This study proposes a 10 MW distributed wind energy scheme using micro wind turbines (WT) of horizontal (HAWT) and vertical axis (VAWT) configurations. These units are rated less than 500 W, and the scheme is hereafter referred to as mWT10. mWT10 is compared to the proposed 10 MW medium WT farm by the Barbados Light and Power Company (BL and P). The economic bottom line is the levelized cost of electricity (LCOE). The results highlight the BL and P proposal as the best economic option at BDS$0.19 per kWh, while that of both mWT10 configurations exceeds the conventional cost of BDS$0.25 by two to nine times. This is attributed to significantly higher relative installation and operational costs. However, the financial gap between mWT10 LCOE and the retail price of electricity is much smaller due to a large fuel surcharge passed on to each customer. Annual additional benefits of using wind energy include: greenhouse gas emissions savings of 6-23 kt of carbon dioxide; and anavoided fuel costs of BDS$1.5-5.3 million. The distributed mWT10 using HAWTs competes directly with the BL and P farm, however, it provides these benefits without the visual or ecological impacts of the larger machines. Conversely, VAWTs have features that favour a visually discrete and widely repeatable scheme but suffer relatively high costs. Therefore, this study illustrates the great potential of small wind turbines to be competitive with conventional wind farms, thus challenging the small wind industry to meet its potential by producing reliable and robust machines at lower cost. (author)

  17. SU-E-T-570: Management of Radiation Oncology Patients with Cochlear Implant and Other Bionic Devices in the Brain and Head and Neck Regions

    International Nuclear Information System (INIS)

    Purpose: To investigate the current status of clinical usage of cochlear implant (CI) and other bionic devices (BD) in the brain and head and neck regions (BH and N) and their management in patients during radiotherapy to ensure patient health and safety as well as optimum radiation delivery. Methods: Literature review was performed with both CIs and radiotherapy and their variants as keywords in PubMed, INSPEC and other sources. The focus was on CIs during radiotherapy, but it also included other BDs in BHȦN, such as auditory brainstem implant, bionic retinal implant, and hearing aids, among others. Results: Interactions between CIs and radiation may cause CIs malfunction. The presence of CIs may also cause suboptimum dose distribution if a treatment plan was not well designed. A few studies were performed for the hearing functions of CIs under irradiations of 4 MV and 6 MV x-rays. However, x-rays with higher energies (10 to 18 MV) broadly used in radiotherapy have not been explored. These higher energetic beams are more damaging to electronics due to strong penetrating power and also due to neutrons generated in the treatment process. Modern CIs are designed with more and more complicated integrated circuits, which may be more susceptible to radiation damage and malfunction. Therefore, careful management is important for safety and treatment outcomes. Conclusion: Although AAPM TG-34, TG-63, and TG-203 (update of TG-34, not published yet) reports may be referenced for management of CIs and other BDs in the brain and H and N regions, a site- and device-specified guideline should be developed for CIs and other BDs. Additional evaluation of CI functions under clinically relevant set-ups should also be performed to provide clinicians with better knowledge in clinical decision making

  18. Correlation Between Birth Defects and Dietary Nutrition Status in a High Incidence Area of China1

    Institute of Scientific and Technical Information of China (English)

    BAO-YUAN ZHANG; QING-SHAN ZHANG; JIN ZHAO; YU-FU QIN; XIU-FENG YANG; GONG CHEN; JU-FEN LIU; XIN-MING SONG; XIAO-YING ZHENG; TING ZHANG; LIANG-MING LIN; FANG WANG; RUO-LEI XIN; XUE GU; YU-NA HE; DONG-MEI YU; PEI-ZHEN LI

    2008-01-01

    Objective To investigate the association between birth defects and dietary nutrient intake in a high risk area of China.Methods A dietary survey was performed and serum folic acid was measured in women whose pregnancy was affected by neural tube defects(NTDs)or unaffected by any birth defects(BDs)in Zhongyang and Jiaokou Counties in Shanxi Province of China.Results The local average censureption of foods including dark green vegetables,fluits,fat and meat,and nutrient intake(e.g.energy,protein,retinol,riboflavin,vitamin E,and selenium)were lower than the national average level.In women of childbearing age,these regions,the intake of nutrients was much lower than the recommended nutrient intake(9%-77%)The case-centrel dietary nutrition smdv of women whose pregnancy was affected bv BDs(including MTDs and congenital heart defects)demonstrated that,in early pregnancy,adequate nutrition(I.e.eating meat,fresh vegetables,fruit more than once a week)was a protective factor,while eating germinated potatoes was a risk factor.The geometrical mean(p5-p95)of serum folic acid in women with NTD birth defects was 9.6 nmol/L(3.6,23.03),which was significantly lower than that in normal women(14.03 nmol/L). Conclusion Wemen of childbearing age in the two counties of Shanxi Province,Chim,have a marked insufficient intake of some nutrients,especially folic acid,zinc,vitamins A and B12.This nutrient deficiency may be an important risk factor for the high prevalence of birth defects in these regions.Therefore,adequate dietary nutrition in early pregnancy can prevent BDs.

  19. Effect of meta-carborane on segmental dynamics in a bimodal Poly(dimethylsiloxane) network

    Energy Technology Data Exchange (ETDEWEB)

    Lewicki, J; Maxwell, R S; Patel, M; Herberg, J; Swain, A C; Liggat, J; Pethrick, R

    2008-06-11

    Bimodal networks of polydimethylsiloxane (PDMS) filled with varying amounts of icosahedral meta-carborane (m-CB) have been developed and characterized by broadband dielectric spectroscopy (BDS) and static {sup 1}H Multiple Quantum Nuclear Magnetic Resonance (MQ NMR). Both BDS and MQ NMR showed evidence for a decrease in the polymer chain dynamics. BDS spectra quantified a normal-mode relaxation near 40 Hz at 40 C. The frequency maximum observed for filled samples decreased with increasing m-CB content until contents greater than 5 wt. %. The width of the relaxation spectrum increased with the addition of small quantities of filler and decreased with filler contents greater that 5 wt. %. Agglomeration effects were observed at loadings greater than 5 wt % as manifest by the onset of low frequency Maxwell-Wagner-Sillars (MWS) processes. The MQ NMR data allowed the characterization of distributions of the residual dipolar couplings, <{Omega}{sub d}> and thus in the dynamic order parameter, Sb, consistent with the bimodal network architecture expected from the synthesis protocol used. Upon addition of less than 10 wt.% m-CB filler, the mean <{Omega}{sub d}> for the longer chains increased by 46% and the width of the distribution increased by 33%. The mean <{Omega}{sub d}> for the shorter chains increased by much less, indicative of preferential dispersion of the filler particles in the long chain domains of the network structure. We conclude that the mechanism of reinforcement is likely a free volume space filling at low loadings transitioning to complex molecular filler and polymer chain interaction phenomena at higher loadings.

  20. Bilateral differences in the net joint torques during the squat exercise.

    Science.gov (United States)

    Flanagan, Sean P; Salem, George J

    2007-11-01

    Bilateral movements are common in human movement, both as exercises and as daily activities. Because the movement patterns are similar, it is often assumed that there are no bilateral differences (BDs; differences between the left and right sides) in the joint torques that are producing these movements. The aim of this investigation was to test the assumption that the joint torques are equal between the left and right lower extremities by quantifying BDs during the barbell squat. Eighteen recreationally trained men (n = 9) and women (n = 9) completed 3 sets of 3 repetitions of the squat exercise, under 4 loading conditions: 25, 50, 75, and 100% of their 3 repetition maximum, while instrumented for biomechanical analysis. The average net joint moment (ANJM) and maximum flexion angle (MFA) for the hip, knee, and ankle as well as the average vertical ground reaction force (AVGRF) and the average distance from the ankle joint center to the center of pressure (ADCOP) were calculated. Group mean and individual data were analyzed (alpha = 0.05). At each joint, there was a significant main effect for side and load, no main effect for gender, with few significant interactions. The hip ANJM was 12.4% larger on the left side, the knee ANJM was 13.2% larger on the right side, and the ankle ANJM was 16.8% larger on the left side. Differences in MFAs between sides were less than 2 degrees for all 3 joints (all p > 0.20 except for the knee at 75% [p = 0.024] and 100% [p = 0.025]), but the AVGRF and the ADCOP were 6% and 11% larger on the left side. Few subjects exhibited the pattern identified with the group mean data, and no subject exhibited nonsignificant BDs for all 3 joints. These findings suggest that joint torques should not be assumed to be equal during the squat and that few individual subjects follow the pattern exhibited by group mean data.

  1. Spin transport at the international linear collider and its impact on the measurement of polarization

    Energy Technology Data Exchange (ETDEWEB)

    Beckmann, Moritz

    2013-12-15

    At the planned International Linear Collider (ILC), the longitudinal beam polarization needs to be determined with an unprecedented precision. For that purpose, the beam delivery systems (BDS) are equipped with two laser Compton polarimeters each, which are foreseen to achieve a systematic uncertainty of {<=} 0.25 %. The polarimeters are located 1.6 km upstream and 150 m downstream of the e{sup +}e{sup -} interaction point (IP). The average luminosity-weighted longitudinal polarization P{sup lumi}{sub z}, which is the decisive quantity for the experiments, has to be determined from these measurements with the best possible precision. Therefore, a detailed understanding of the spin transport in the BDS is mandatory to estimate how precise the longitudinal polarization at the IP is known from the polarimeter measurements. The envisaged precision for the propagation of the measurement value is {<=} 0.1 %. This thesis scrutinizes the spin transport in view of the achievable precision. A detailed beamline simulation for the BDS has been developed, including the simulation of the beam-beam collisions at the IP. The following factors which might limit the achievable precision is investigated: a variation of the beam parameters, the beam alignment precision at the polarimeters and the IP, the bunch rotation at the IP, the detector magnets, the beam-beam collisions, the emission of synchrotron radiation and misalignments of the beamline elements. In absence of collisions, a precision of 0.085% on the propagation of the measured longitudinal polarization has been found achievable. This result however depends mainly on the presumed precisions for the parallel alignment of the beam at the polarimeters and for the alignment of polarization vector. In presence of collisions, the measurement at the downstream polarimeter depends strongly on the intensity of the collision and the size of the polarimeter laser spot. Therefore, a more detailed study of the laser-bunch interaction is

  2. Rat Cardiomyocytes Express a Classical Epithelial Beta-Defensin

    Directory of Open Access Journals (Sweden)

    Annika Linde

    2008-01-01

    Full Text Available Beta-defensins (BDs are classical epithelial antimicrobial peptides of immediate importance in innate host defense. Since recent studies have suggested that certain BDs are also expressed in non-traditional tissues, including whole heart homogenate and because effector molecules of innate immunity and inflammation can influence the development of certain cardiovascular disease processes, we hypothesized that BDs are produced by cardiomyocytes as a local measure of cardioprotection against danger signals. Here we report that at least one rat beta-defensin, rBD1, is expressed constitutively in cardiomyocytes specifically isolated using position-ablation-laser-microdissection (P.A.L.M. Microlaser Technologies. RT-PCR analysis showed expression of a single 318 bp transcript in adult rat heart (laser-excised cardiomyocytes and H9c2 cells (neonatal rat heart myoblasts. Moreover, the full length cDNA of rBD1 was established and translated into a putative peptide with 69 amino acid residues. The predicted amino acid sequence of the adult rat cardiac BD-1 peptide displayed 99% identity with the previously reported renal rBD1 and 88, 53, 53 and 50% identity with mouse, human, gorilla and rhesus monkey BD1 respectively. Furthermore, structural analysis of the cardiac rBD1 showed the classical six-cysteine conserved motif of the BD family with an alpha-helix and three beta-sheets. Additionally, rBD1 displayed a significantly greater number of amphoteric residues than any of the human analogs, indicating a strong pH functional dependence in the rat. We suggest that rBD1, which was initially believed to be a specific epithelium-derived peptide, may be also involved in local cardiac innate immune defense mechanisms.

  3. A Sativex®-like combination of phytocannabinoids as a disease-modifying therapy in a viral model of multiple sclerosis

    Science.gov (United States)

    Feliú, A; Moreno-Martet, M; Mecha, M; Carrillo-Salinas, F J; de Lago, E; Fernández-Ruiz, J; Guaza, C

    2015-01-01

    Background and Purpose Sativex® is an oromucosal spray, containing equivalent amounts of Δ9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD)-botanical drug substance (BDS), which has been approved for the treatment of spasticity and pain associated to multiple sclerosis (MS). In this study, we investigated whether Sativex may also serve as a disease-modifying agent in the Theiler's murine encephalomyelitis virus-induced demyelinating disease model of MS. Experimental Approach A Sativex-like combination of phytocannabinoids and each phytocannabinoid alone were administered to mice once they had established MS-like symptoms. Motor activity and the putative targets of these cannabinoids were assessed to evaluate therapeutic efficacy. The accumulation of chondroitin sulfate proteoglycans (CSPGs) and astrogliosis were assessed in the spinal cord and the effect of Sativex on CSPGs production was evaluated in astrocyte cultures. Key Results Sativex improved motor activity – reduced CNS infiltrates, microglial activity, axonal damage – and restored myelin morphology. Similarly, we found weaker vascular cell adhesion molecule-1 staining and IL-1β gene expression but an up-regulation of arginase-1. The astrogliosis and accumulation of CSPGs in the spinal cord in vehicle-infected animals were decreased by Sativex, as was the synthesis and release of CSPGs by astrocytes in culture. We found that CBD-BDS alone alleviated motor deterioration to a similar extent as Sativex, acting through PPARγ receptors whereas Δ9-THC-BDS produced weaker effects, acting through CB2 and primarily CB1 receptors. Conclusions and Implications The data support the therapeutic potential of Sativex to slow MS progression and its relevance in CNS repair. PMID:25857324

  4. SU-E-T-570: Management of Radiation Oncology Patients with Cochlear Implant and Other Bionic Devices in the Brain and Head and Neck Regions

    Energy Technology Data Exchange (ETDEWEB)

    Guo, F.Q; Chen, Z; Nath, R [Yale New Haven Hospital, New Haven, CT (United States); Yale UniversitySchool of Medicine, New Haven, CT (United States)

    2014-06-01

    Purpose: To investigate the current status of clinical usage of cochlear implant (CI) and other bionic devices (BD) in the brain and head and neck regions (BH and N) and their management in patients during radiotherapy to ensure patient health and safety as well as optimum radiation delivery. Methods: Literature review was performed with both CIs and radiotherapy and their variants as keywords in PubMed, INSPEC and other sources. The focus was on CIs during radiotherapy, but it also included other BDs in BHȦN, such as auditory brainstem implant, bionic retinal implant, and hearing aids, among others. Results: Interactions between CIs and radiation may cause CIs malfunction. The presence of CIs may also cause suboptimum dose distribution if a treatment plan was not well designed. A few studies were performed for the hearing functions of CIs under irradiations of 4 MV and 6 MV x-rays. However, x-rays with higher energies (10 to 18 MV) broadly used in radiotherapy have not been explored. These higher energetic beams are more damaging to electronics due to strong penetrating power and also due to neutrons generated in the treatment process. Modern CIs are designed with more and more complicated integrated circuits, which may be more susceptible to radiation damage and malfunction. Therefore, careful management is important for safety and treatment outcomes. Conclusion: Although AAPM TG-34, TG-63, and TG-203 (update of TG-34, not published yet) reports may be referenced for management of CIs and other BDs in the brain and H and N regions, a site- and device-specified guideline should be developed for CIs and other BDs. Additional evaluation of CI functions under clinically relevant set-ups should also be performed to provide clinicians with better knowledge in clinical decision making.

  5. Determination of the Flavonoids from Ginkgo Biloba Extract by High Performance Liquid Chromatography

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    HPLC method for analysis of the flavonoids from ginkgo biloba extract (GBE) was studied. By suitable selection of columns, symmetrical chromatographic peaks were obtained without using acidic modifier in the mobile phase, which can eliminate the time for cleaning the chromatographic system and simplify the analystic method for GBE. Experimental conditions: column: Hypersil BDS C18,5(m×4×250 mm; column temperature: 35(C; mobile phase: 46% methanol-54% water; flow rate: 0.7 mL/min; detection wavelength: 360nm.

  6. CLIC Muon Sweeper Design

    CERN Document Server

    Aloev, A; Gatignon, L; Modena, M; Pilicer, B; Tapan, I

    2016-01-01

    There are several background sources which may affect the analysis of data and detector performans at the CLIC project. One of the important background source is halo muons, which are generated along the beam delivery system (BDS), for the detector performance. In order to reduce muon background, magnetized muon sweepers have been used as a shielding material that is already described in a previous study for CLIC [1]. The realistic muon sweeper has been designed with OPERA. The design parameters of muon sweeper have also been used to estimate muon background reduction with BDSIM Monte Carlo simulation code [2, 3].

  7. Tuning of the Compact Linear Collider Beam Delivery System

    CERN Document Server

    Garcia, H; Inntjore Levinsen, Y; Latina, A; Tomas, R; Snuverink, J

    2014-01-01

    Tuning the Compact Linear Collider (CLIC) BeamDelivery System (BDS), and in particular the Final Focus (FF), is a challenging task. In simulations without misalignments, the goal is to reach 120%o f the nominal luminosity target, in order to allow for 10% loss due to static imperfections, and another 10% loss from dynamic imperfections. Various approaches have been considered to correct the magnet misalignments, including 1-1 correction, Dispersion Free Steering (DFS), and several minimization methods utilizing multipole movers. In this paper we report on the recent advancements towards a feasible tuning approach that reaches the required luminosity target.

  8. 牙周组织中β-防御素与TOLL样受体表达水平的研究%Study on the expression of human beta defensins and TOLL like receptors in the periodontal tissues

    Institute of Scientific and Technical Information of China (English)

    王芳; 张海云; 何萍; 赵玉红; 蒋静颖

    2016-01-01

    Objective To study the expression of human Bata Defensins ( hBDs) and Toll like receptors ( TLRs) in periodontal tis⁃sues and the changes of the expression level in chronic periodontitis. Methods 23 chronic periodontitis patients and 15 healthy con⁃trols were selected in the department of stomatology. The periodontal tissues were collected in the patients with chronic periodontitis and healthy controls. The expression levels of TLRs and hBDs were analyzed by real⁃time quantitative PCR and immunohistochemistry. Re⁃sults The expression levels of TLRs and hBDs in the periodontal tissues of healthy individuals and patients with chronic periodontitis were changed, but the changing trend was different. Conclusion The expression levels of hBDs and TLRs in the periodontal tissues were analyzed in this study. According to the research results, the expression level of these two kinds of endogenous immune factors in the periodontal tissues may change with the presence of periodontitis. Because of the different expression sites, it is suggested that there are interactions between these two endogenous immune factors in the process of chronic periodontitis.%目的:研究人β⁃防御素( hBDs)与Toll样受( TLRs)体这两大类免疫物质在牙周组织表达以及由于慢性牙周炎引起的表达水平变化。方法在口腔科门诊征集23例慢性牙周炎患者和15例健康对照者,分别在其进行牙周手术和拔牙手术时收集牙周组织,通过实时定量PCR和免疫组化实验分析hBDs和TLRs的表达水平变化。结果作为牙周炎相关的免疫因子, hBDs和TLRs在健康人和慢性牙周炎患者的牙周组织中的表达水平均有变化,但变化趋势有所不同。结论防御素和TLRs在牙周组织中的表达水平因为牙周炎的存在而发生一定的变化。由于表达部位不同,提示在慢性牙周炎进程中,这两大类内源性免疫因子之间也存在相互作用。

  9. Emission Rates and Optical Properties of Pollutants Emitted from a Traditional and an Improved Wood-Burning Cookstove

    Science.gov (United States)

    Kirchstetter, T.; Hadley, O. L.; Preble, C.; Gadgil, A.

    2010-12-01

    Traditional cooking methods in developing regions of the world generate gas and particle phase pollutants that endanger the lives of more than a billion people and contribute appreciably to the burden of climate-changing particles in the atmosphere. This presentation compares pollutant emissions from the traditional “three-stone fire” and an improved cookstove developed for refugees in Darfur: the Berkeley-Darfur Stove (BDS). The BDS was designed for increased fuel efficiency to decrease the risk of assault that women often face when gathering fuel wood. Reduced pollutant exposure and climate impact are potential co-benefits. Testing of these stoves at the Lawrence Berkeley National Laboratory facility includes 1-Hz measurements of concentrations of particulate matter, black carbon, carbon monoxide, and carbon dioxide; coefficients of particle light absorption and scattering; and absorption Angstrom exponent. Absorption and scattering coefficients were measured at 532 nm using a photoacoustic absorption instrument equipped with a reciprocal nephelometer. The BDS heated food faster and consumed less wood in cooking tests compared to the three-stone fire. The BDS emitted less carbon monoxide and particulate matter but comparable mass of black carbon compared to the three-stone fire for the same cooking task. Values of the absorption Angstrom exponent ranged from about 1 - 3, indicating the emission of both black carbon and light-absorbing organic carbon (i.e., brown carbon). Values of (dry) aerosol single scattering albedo were mostly in the range of 0.25 - 0.55, indicating that the emitted particles tend to absorb more light than they scatter. Our analysis considered the variability of pollutant emissions during different phases of the fire. Particulate matter emissions were highest during the first several minutes of cooking, which included igniting the wood, whereas carbon monoxide emissions were highest during the last several minutes of cooking when

  10. Determination of racecadotril by HPLC in capsules

    OpenAIRE

    Prabu S; Singh T; Joseph A; Kumar C; Shirwaikar A

    2007-01-01

    A simple, precise and rapid RP-HPLC method was developed for the determination of racecadotril in a pharmaceutical formulation using gemfibrozil as internal standard. Ratio of the peak area of analyte to internal standard was used for quantification. The chromatographic separation was carried out by using a Reverse Phase C18 column (BDS-Hypersil). The mobile phase consisting of a mixture of 20 mM phosphate buffer (pH 3.5) and acetonitrile in the ratio of (40:60) with detection at 230 nm at a ...

  11. Issues of Stability and Ground Motion in ILC

    Energy Technology Data Exchange (ETDEWEB)

    Seryi, Andrei; Hendrickson, Linda; White, Glen; /SLAC

    2006-02-03

    Stability of International Linear Collider is determined by the stability of the site, additional noises of beamline component, energy and kicker jitter, and performance of train-to-train and intratrain feedback. Stability goals in terms of the beam jitter at the end of the linac, in BDS and at the IP are discussed in this paper, and translated to stability goals for the site and for component jitter. Present status of stability studies is reviewed and feasibility of achieving the stability goals is discussed.

  12. Determination of Vitamin B12 in Vitamin B12 Compound Ointment- Ⅰ by HPLC%复方维生素B12软膏Ⅰ号中维生素B12的HPLC测定

    Institute of Scientific and Technical Information of China (English)

    杨谊; 李兵; 史学慧

    2004-01-01

    建立了HPLC法测定复方维生素B12软膏Ⅰ号中维生素B12的含量.采用Hypersll BDS C18柱,流动相为乙腈-0.05mol/L磷酸二氢钾溶液(15:85),检测波长360nm.维生素B12在0.16~0.8μg范围内线性关系良好(r=0.9995),平均回收率为98.4%,RSD为0.9%.

  13. Gasoline Biodesulfurization DE-FC07-97ID13570 FINAL REPORT; FINAL

    International Nuclear Information System (INIS)

    Nine strains were identified to grow with gasoline as sole sulfur source. Two different genes were cloned from Gordonia terrae KGB1 and tested for the ability to support gasoline BDS. The first of these, fmoA, was cloned by screening a KGB1 gene library for the ability to convert indole to indigo (a sulfur-regulated capability in KGB1). The fmoA gene was overexpressed in a gasoline tolerant strain of Pseudomonas putida PpG1 and the recombinant strain was shown to convert thiophene to a dimer of thiophene sulfoxide at rates nearly two orders of magnitude higher than KGB1 could catalyze the reaction. Despite this high activity the recombinant PpG1 was unable to demonstrate any activity against gasoline either in shake flask or in bench-scale gasoline BDS bioreactor. A second gene (toeA) was cloned from KGB1 and shown to support growth of Rhodococcus erythropolis JB55 on gasoline. The toeA gene was also identified in another gasoline strain T. wratislaviensis EMT4, and was identified as a homolog of dszA from R. erythropolis IGTS8. Expression of this gene in JB55 supported conversion of DBTO2 (the natural substrate for DszA) to HPBS, but activity against gasoline was low and BDS results were inconsistent. It appeared that activity was directed against C2- and C3-thiophenes. Efforts to increase gene expression by plasmid manipulation, by addition of flavin reductase genes, or by expression in PpG1 were unsuccessful. The DszC protein (DBT monooxygenase) from IGTS8 has very little activity against the sulfur compounds in gasoline, but a mutant enzyme with a substitution of phenylalanine for valine at position 261 was shown to have an altered substrate range. This alteration resulted in increased activity against gasoline, with activity towards mainly C3- and C4-thiophenes and benzothiophene. A mutant library of dszB was constructed by RACHITT (W. C. Coco et al., DNA shuffling method for generating highly recombined genes and evolved enzymes. 2001. Nature Biotech. 19

  14. Analytic structure of the n=7 scattering amplitude in N=4 SYM theory at multi-Regge kinematics. Conformal Regge pole contribution

    Energy Technology Data Exchange (ETDEWEB)

    Bartels, Jochen; Kormilitzin, Andrey [Hamburg Univ. (Germany). II. Inst. fuer Theoretische Physik; Lipatov, Lev [Hamburg Univ. (Germany). II. Inst. fuer Theoretische Physik; St. Petersburg Nuclear Physics Institute, St. Petersburg (Russian Federation)

    2013-11-15

    We investigate the analytic structure of the 2 {yields} 5 scattering amplitude in the planar limit of N=4 SYM in multi-Regge kinematics in all physical regions. We demonstrate the close connection between Regge pole and Regge cut contributions: in a selected class of kinematic regions (Mandelstam regions) the usual factorizing Regge pole formula develops unphysical singularities which have to be absorbed and compensated by Regge cut contributions. This leads, in the corrections to the BDS formula, to conformal invariant 'renormalized' Regge pole expressions in the remainder function. We compute these renormalized Regge poles for the 2 {yields} 5 scattering amplitude.

  15. First Observation of the Decay D_s^+ to proton anti-neutron

    CERN Document Server

    Athar, S B; Yelton, J; Rubin, P; Eisenstein, B I; Karliner, I; Mehrabyan, S; Lowrey, N; Selen, M; White, E J; Wiss, J; Mitchell, R E; Shepherd, M R; Besson, D; Pedlar, T K; Cronin-Hennessy, D; Gao, K Y; Hietala, J; Kubota, Y; Klein, T; Lang, B W; Poling, R; Scott, A W; Zweber, P; Dobbs, S; Metreveli, Z; Seth, K K; Tomaradze, A G; Libby, J; Powell, A; Wilkinson, G; Ecklund, K M; Love, W; Savinov, V; López, A; Méndez, H; Ramírez, J; Ge, J Y; Miller, D H; Shipsey, I P J; Xin, B; Adams, G S; Anderson, M; Cummings, J P; Danko, I; Hu, D; Moziak, B; Napolitano, J; He, Q; Insler, J; Muramatsu, H; Park, C S; Thorndike, E H; Yang, F; Artuso, M; Blusk, S; Khalil, S; Li, J; Mountain, R; Nisar, S; Randrianarivony, K; Sultana, N; Skwarnicki, T; Stone, S; Wang, J C; Zhang, L M; Bonvicini, G; Cinabro, D; Dubrovin, M; Lincoln, A; Naik, P; Rademacker, J; Asner, D M; Edwards, K W; Reed, J; Briere, R A; Ferguson, T; Tatishvili, G; Vogel, H; Watkins, M E; Rosner, J L; Alexander, J P; Cassel, D G; Duboscq, J E; Ehrlich, R; Fields, L; Gibbons, L; Gray, R; Gray, S W; Hartill, D L; Heltsley, B K; Hertz, D; Hunt, J M; Kandaswamy, J; Kreinick, D L; Kuznetsov, V E; Ledoux, J; Mahlke-Krüger, H; Mohapatra, D; Onyisi, P U E; Patterson, J R; Peterson, D; Riley, D; Ryd, A; Sadoff, A J; Shi, X; Stroiney, S; Sun, W M; Wilksen, T

    2008-01-01

    Using e^+e^- -> D_s^*+ D_s^- data collected near the peak D_s production energy, E_cm=4170 MeV, with the CLEO-c detector, we present the first observation of the decay D_s^+ -> proton anti-neutron. We measure a branching fraction B(D_s^+ -> p anti-n = (1.30 +- 0.36 +0.12 -0.16) x 10^-3. This is the first observation of a charmed meson decaying into a baryon-antibaryon final state.

  16. Absolute Measurement of Hadronic Branching Fractions of the D_s^+ Meson

    CERN Document Server

    Alexander, J; Cassel, D G; Duboscq, J E; Ehrlich, R; Fields, L; Gibbons, L; Gray, R; Gray, S W; Hartill, D L; Heltsley, B K; Hertz, D; Jones, C D; Kandaswamy, J; Kreinick, D L; Kuznetsov, V E; Mahlke-Krüger, H; Mohapatra, D; Onyisi, P U E; Patterson, J R; Peterson, D; Riley, D; Ryd, A; Sadoff, A J; Shi, X; Stroiney, S; Sun, W M; Wilksen, T; Athar, S B; Patel, R; Yelton, J; Rubin, P; Eisenstein, B I; Karliner, I; Mehrabyan, S; Lowrey, N; Selen, M; White, E J; Wiss, J; Mitchell, R E; Shepherd, M R; Besson, D; Pedlar, T K; Cronin-Hennessy, D; Gao, K Y; Hietala, J; Kubota, Y; Klein, T; Lang, B W; Poling, R; Scott, A W; Zweber, P; Dobbs, S; Metreveli, Z; Seth, K K; Tomaradze, A G; Libby, J; Powell, A; Wilkinson, G; Ecklund, K M; Love, W; Savinov, V; López, A; Méndez, H; Ramírez, J; Ge, J Y; Miller, D H; Sanghi, B; Shipsey, I P J; Xin, B; Adams, G S; Anderson, M; Cummings, J P; Danko, I; Hu, D; Moziak, B; Napolitano, J; He, Q; Insler, J; Muramatsu, H; Park, C S; Thorndike, E H; Yang, F; Artuso, M; Blusk, S; Khalil, S; Li, J; Mountain, R; Nisar, S; Randrianarivony, K; Sultana, N; Skwarnicki, T; Stone, S; Wang, J C; Zhang, L M; Bonvicini, G; Cinabro, D; Dubrovin, M; Lincoln, A; Rademacker, J; Asner, D M; Edwards, K W; Naik, P; Briere, R A; Ferguson, T; Tatishvili, G; Vogel, H; Watkins, M E; Rosner, J L

    2008-01-01

    The branching fractions of D_s meson decays serve to normalize many measurements of processes involving charm quarks. Using 298 /pb of e+ e- collisions recorded at a center of mass energy of 4.17 GeV, we determine absolute branching fractions for eight D_s decays with a double tag technique. In particular we determine the branching fraction B(D_s -> K- K+ pi+) = (5.50 +- 0.23 +- 0.16)%, where the uncertainties are statistical and systematic respectively. We also provide partial branching fractions for kinematic subsets of the K- K+ pi+ decay mode.

  17. Observation of Ds1(2536)+ -> D+pi-K+ and angular decomposition of Ds1(2536)+ -> D*+K0S

    CERN Document Server

    Balagura, V; Aihara, H; Arinstein, K; Aulchenko, V; Aushev, T; Bakich, A M; Barberio, E; Bay, A; Belous, K S; Bhardwaj, V; Bitenc, U; Bondar, A; Bozek, A; Bracko, M; Brodzicka, J; Browder, T E; Chang, M C; Chao, Y; Chen, A; Chen, W T; Cheon, B G; Chistov, R; Cho, I S; Choi, Y; Dalseno, J; Danilov, M; Drutskoy, A; Eidelman, S; Epifanov, D; Gabyshev, N; Garmash, A; Golob, B; Ha, H; Haba, J; Hara, T; Hastings, N C; Hayasaka, K; Hayashii, H; Hazumi, M; Heffernan, D; Hoshi, Y; Hou, W S; Hyun, H J; Inami, K; Ishikawa, A; Ishino, H; Itoh, R; Iwasaki, M; Iwasaki, Y; Kah, D H; Kaji, H; Katayama, N; Kawai, H; Kawasaki, T; Kichimi, H; Kim, H J; Kim, H O; Kim, Y J; Kinoshita, K; Korpar, S; Krizan, P; Krokovny, P; Kuo, C C; Kuzmin, A; Kwon, Y J; Lange, J S; Lee, M J; Lee, S E; Lesiak, T; Limosani, A; Lin, S W; Liu, Y; Liventsev, D; Mandl, F; McOnie, S; Medvedeva, T; Mitaroff, W A; Miyake, H; Miyata, H; Miyazaki, Y; Mizuk, R; Mohapatra, D; Moloney, G R; Nagasaka, Y; Nakano, E; Nakao, M; Nakazawa, H; Natkaniec, Z; Nishida, S; Nitoh, O; Ogawa, S; Ohshima, T; Okuno, S; Olsen, S L; Ostrowicz, W; Ozaki, H; Pakhlov, P; Pakhlova, G; Palka, H; Park, C W; Peak, L S; Pestotnik, R; Piilonen, L E; Sakai, Y; Schneider, O; Senyo, K; Shapkin, M; Shen, C P; Shibuya, H; Shiu, J G; Somov, A; Stanic, S; Staric, M; Sumiyoshi, T; Tamai, K; Tanaka, M; Taylor, G N; Teramoto, Y; Tikhomirov, I; Uehara, S; Ueno, K; Uglov, T; Unno, Y; Uno, S; Urquijo, P; Usov, Yu; Varner, G; Vervink, K; Villa, S; Vinokurova, A; Wang, C C; Wang, C H; Wang, M Z; Wang, P; Wang, X L; Watanabe, Y; Won, E; Yabsley, B D; Yamaguchi, A; Yamashita, Y; Yamauchi, M; Zhang, Z P; Zhilich, V; Zhulanov, V; Zupanc, A; Zyukova, O

    2007-01-01

    Using 462/fb of e+e- annihilation data recorded by the Belle detector, we report the first observation of the decay Ds1(2536)+ -> D+pi-K+. The ratio of branching fractions B(Ds1+ -> D+pi-K+)/B(Ds1+ -> D*+K0) is measured to be (3.27+-0.18+-0.37)%. We also study the angular distributions in the Ds1(2536)+ -> D*+K0S decay and measure the ratio of D- and S-wave amplitudes. The S-wave dominates, with a partial width of Gamma_S/Gamma_total=0.72+-0.05+-0.01.

  18. Academic advising and student support: Help-seeking behaviors among Saudi dental undergraduate students

    OpenAIRE

    Asim Al-Ansari; Maha El Tantawi; Maha AbdelSalam; Fahad Al-Harbi

    2015-01-01

    Objective: The purpose of this study was to assess the use of and satisfaction with the academic-advising and student-support systems available to undergraduate students in the College of Dentistry at the University of Dammam. In addition, the study aimed to also identify factors that explained the help-seeking behavior of students which they used to solve academic issues. Materials and methods: Students enrolled in the five-year Bachelor of Dental Surgery (BDS) program in 2012–13 and 2013...

  19. Gasoline Biodesulfurization DE-FC07-97ID13570 FINAL REPORT

    Energy Technology Data Exchange (ETDEWEB)

    Pienkos, Philip T.

    2002-01-15

    Nine strains were identified to grow with gasoline as sole sulfur source. Two different genes were cloned from Gordonia terrae KGB1 and tested for the ability to support gasoline BDS. The first of these, fmoA, was cloned by screening a KGB1 gene library for the ability to convert indole to indigo (a sulfur-regulated capability in KGB1). The fmoA gene was overexpressed in a gasoline tolerant strain of Pseudomonas putida PpG1 and the recombinant strain was shown to convert thiophene to a dimer of thiophene sulfoxide at rates nearly two orders of magnitude higher than KGB1 could catalyze the reaction. Despite this high activity the recombinant PpG1 was unable to demonstrate any activity against gasoline either in shake flask or in bench-scale gasoline BDS bioreactor. A second gene (toeA) was cloned from KGB1 and shown to support growth of Rhodococcus erythropolis JB55 on gasoline. The toeA gene was also identified in another gasoline strain T. wratislaviensis EMT4, and was identified as a homolog of dszA from R. erythropolis IGTS8. Expression of this gene in JB55 supported conversion of DBTO2 (the natural substrate for DszA) to HPBS, but activity against gasoline was low and BDS results were inconsistent. It appeared that activity was directed against C2- and C3-thiophenes. Efforts to increase gene expression by plasmid manipulation, by addition of flavin reductase genes, or by expression in PpG1 were unsuccessful. The DszC protein (DBT monooxygenase) from IGTS8 has very little activity against the sulfur compounds in gasoline, but a mutant enzyme with a substitution of phenylalanine for valine at position 261 was shown to have an altered substrate range. This alteration resulted in increased activity against gasoline, with activity towards mainly C3- and C4-thiophenes and benzothiophene. A mutant library of dszB was constructed by RACHITT (W. C. Coco et al., DNA shuffling method for generating highly recombined genes and evolved enzymes. 2001. Nature Biotech. 19

  20. "edo jal̀qkina üts̀varòkaetus ma vaelda ..." : [luuletused] / Andreas Kalkun

    Index Scriptorium Estoniae

    Kalkun, Andreas, 1977-

    2002-01-01

    Sisu: "edo jal̀qkina üts̀varòkaetus ma vaelda ..." ; "tsirguq ku kiviq no satassõ taivast aràlaq ..." ; "vahtsõq silmäq pitsitä pääluu sisse ..." ; "tõppõ tõmmat haigõst ma haarõt jal̀ki ..." ; "arsatas njago sisse aigopiteh ..." ; "rühkeq yks jumalat pallõlda jaloh ..." ; "mu süä om no süüdläne täǹtäseq kuvvõ ..." ; "halvaq haavaq häitsese veiga silmih. Eluloolisi andmeid autori kohta lk. 379

  1. Krabba : Automatisk pallkragsmontering

    OpenAIRE

    Persson, Edvin

    2012-01-01

    Företaget Goodtech Solutions AB har en prototyp av en maskin som behöver genomgå ett förbättringsarbete. Maskinen monterar automatiskt pallkragar på pall med hjälp av en robotarm. Det här arbetet fokuserar på den del av maskinen som hanterar pallkragen vid montering. Denna del kallas för krabba p.g.a. dess utseende. Målet är att genomföra förbättringsarbetet och arbetes syfte är att vara ett förbättringsunderlag för maskinen inför en framtida marknadslansering. För att montera en pallkrage lå...

  2. [Fungi isolated from diseased medicinal plants].

    Science.gov (United States)

    Sato, T; Matsuhashi, M; Iida, O

    1992-01-01

    One hundred and forty-four fungal isolates were obtained from diseased Paeonia albiflora Pall. var. trichocarpa Bung., Astragalus membranaceus Bung., Lithospermum erythrorhizon Sieb. et Zucc., Ledebouriella seseloides Wolff and Bupleurum falcatum L. which were collected in the test field of Tsukuba Medicinal Plant Research Station, National Institute of Hygienic Sciences. Most of them were identified into 15 genera containing 8 species. Fungal species presumed to be pathogens of the host plants were as follows: Cladosporium paeoniae, Pestalotia paeoniicola, Glomerella cingulata, Hainesia lythri, Guignardia sp. and Alternaria sp. from P. albiflora, Fusarium spp., Rhizoctonia spp. and Neocosmospora vasinfecta from A. membranaceus, Colletotrichum gloeosporioides from L. erythrorhizon, Rhizoctonia sp., Fusarium spp., Phoma sp. and Pyrenochaeta sp. from L. seseloides, and Fusarium sp., Alternaria alternata, Phyllosticta sp., Phoma sp., Phomopsis sp. and C. gloeosporioides from B. falcatum. Roots of B. falcatum were found to be parasitized by Meloidogyne sp. PMID:1364438

  3. Comparison of anatomical characteristics of leaves and flowers of Crataegus and some species of Rosaceae family

    Directory of Open Access Journals (Sweden)

    V.A. Kiryanova

    2014-04-01

    Full Text Available The present work shows the results of microscopy of Crataegus sanguinea Pall. leaves with flowers (Crataegi flores cum folia, which is considered as a perspective form of medicinal raw material, and the hypothetical plant adulterants – Amelanchier ovalis Medik., Prunus subgen. Cerasus (Mill. A. Gray, Pyrus communis L., Aronia melanocarpa (Michx. Elliott (Rosaceae. Parts of leaves and flowers of stated plants were subjected to anatomical investigation and comparative studies. Microscopical characteristics of leaves and flowers, which make possible to distinguish Crataegus from other species, were detected. The obtained data can be applied for the development of pharmacopoeial article “Crataegi Flores cum folia” for the XII edition of the Russian State Pharmacopoeia.

  4. Aerosol filtration with steel fiber filters

    Science.gov (United States)

    Bergman, W.; Wilson, K.; Larsen, G.; Lopez, R.

    1993-04-01

    An experimental study has been conducted of aerosol penetration through a new high efficiency steel fiber filter and filter media that was developed in cooperation with Pall Corporation. Previous studies have shown that sintered steel fiber media have significant improvements in higher filter efficiency and lower pressure drop than the previous steel filter technology based on sintered powder metal media. In the present study, measurements were made of the penetration of dioctyl sebacate (DOS) aerosols through flat sheet samples, pleated cartridge filters, and a 1000 cfm filter having 64 cartridges housed in a 2 x 2 x 1 ft. frame. The steel fiber media used in our study consists of 2 micron diameter stainless steel (316 L) fibers sintered together into sheets.

  5. Managing ADHD in Adulthood: A Meta-Synthesis of How Adults Diagnosed With ADHD Manage

    DEFF Research Database (Denmark)

    Bjerrum, Merete; Larsen, Palle; Pedersen, Preben Ulrich

    , manage to live, life impairment, social life skills, attitude, coping behaviour, academic functioning, social adjustment, interpersonal relation, family health, social support, adult 19-44 years, middle aged 45-64 years. Results Four themes emerged from the included studies: ‘Being different from others......Managing ADHD in adulthood A meta-synthesis of how adults diagnosed with ADHD manage life with the symptoms Merete Bjerrum, Associate Professor, PhD, Department of Public Health, Aarhus University, Denmark and Danish Centre for Systematic Review in Nursing; Palle Larsen, MScN, PhD-student, Deputy...... director, Danish Centre for Systematic Review in Nursing, Denmark, and Preben Ulrich Pedersen, PhD Director, Danish Centre for Systematic Review in Nursing, Denmark Background Attention Deficit-Hyperactivity Disorder (ADHD) is related to four dimensions: inattentiveness, restlessness, impulsivity...

  6. TESTING OF A FULL-SCALE ROTARY MICROFILTER FOR THE ENHANCED PROCESS FOR RADIONUCLIDES REMOVAL

    Energy Technology Data Exchange (ETDEWEB)

    Herman, D; David Stefanko, D; Michael Poirier, M; Samuel Fink, S

    2009-01-01

    Savannah River National Laboratory (SRNL) researchers are investigating and developing a rotary microfilter for solid-liquid separation applications in the Department of Energy (DOE) complex. One application involves use in the Enhanced Processes for Radionuclide Removal (EPRR) at the Savannah River Site (SRS). To assess this application, the authors performed rotary filter testing with a full-scale, 25-disk unit manufactured by SpinTek Filtration with 0.5 micron filter media manufactured by Pall Corporation. The filter includes proprietary enhancements by SRNL. The most recent enhancement is replacement of the filter's main shaft seal with a John Crane Type 28LD gas-cooled seal. The feed material was SRS Tank 8F simulated sludge blended with monosodium titanate (MST). Testing examined total insoluble solids concentrations of 0.06 wt % (126 hours of testing) and 5 wt % (82 hours of testing). The following are conclusions from this testing.

  7. 威灵仙的成分、药理活性和临床应用的研究进展

    Institute of Scientific and Technical Information of China (English)

    赵燕强; 杨立新; 张宪民; 邱明华

    2008-01-01

    本文对中药威灵仙的有关研究进行了综述.主要为威灵仙(Clematis chinensis Osbeck)、棉团铁线莲(Clematis hexapetala Pall.)和东北铁线莲(Clematis manshurica Rupr.)成分中发现的化合物.包括皂甙、黄酮、挥发油等,并对新发现的药理作用进行阐述,也说明了治疗一些疾病的机制和起作用的化合物,还对威灵仙的临床应用进行了介绍.

  8. 9种铁线莲属药用植物的比较鉴别

    Institute of Scientific and Technical Information of China (English)

    胡玉涛; 周政昆

    2002-01-01

    @@ 毛茛科铁线莲属植物约有300种,我国有108种[1].其中作为正品威灵仙入药的为威灵仙Clematis chinesis Osbeck、棉团铁线莲Clematis hexapetala Pall.和东北铁线莲Clematis manshurica Rupr.的干燥根及根茎[2].目前市场上作为威灵仙流通的药材种类较多,而且性状相似,难以区别.现对9种铁线莲属药用植物的形态进行比较、鉴别,为今后的研究提供依据.

  9. 蒙药才棉团铁线莲化学成分和药理研究进展

    Institute of Scientific and Technical Information of China (English)

    巴达日呼; 房玉良

    2009-01-01

    蒙药才棉团铁线莲clematis hexapetala pall.具有破痞,调温, "协日乌紊",止腐,消肿,止泻之功效.临床上主治寒痞,消化不良,寒性"协日乌素"病,"吾雅曼"病,黄水疮,疮疡,水肿,寒泻,祛除各种瘤的功效.所含的化学成分黄酮类、糖类、皂苷类、白头翁索、生物碱、挥发油和药理作用抗肿瘤、降血压、降糖、抑菌,抗氧化等作用.

  10. Aerobic biotrickling filtration for biogas desulfurization

    OpenAIRE

    Monzón Montebello, Andrea

    2013-01-01

    Es va gestionar l'operació d'un biofiltre percolador (BTF) durant un període total de 990 dies per a la dessulfuració d'un biogàs sintètic contenint 2,000 ppmv d'H2S (≈ 50 g S-H2S·m-3·h-1), utilitzant un material de rebliment aleatori (anelles Pall d'acer inoxidable). Després de l'optimització de l'operació a pH neutre, es va estudiar l'eliminació simultània de metilmercaptà (CH3SH) i H2S. A continuació es va executar la transició ininterrompuda des de 440 dies a pH neutre (6.0 – 6.5) a 550 d...

  11. Guiding young adults at risk

    DEFF Research Database (Denmark)

    Andreasen, Karen Egedal; Rasmussen, Palle Damkjær; Ydesen, Christian

    2016-01-01

    Karen Egedal Andreasen, Palle Rasmussen and Christian Ydesen question in their article, how to guide youth in danger of being marginalised or excluded from society in general and the labour market in particular. They analyse the guidance dimension in the youth in development project as described...... in the project and by the youths participating in the project. The project was designed to facilitate and support transition to an adult life by giving participants social support, feedback, experiences, room for reflection and feeling of acceptance and inclusion. In Denmark all social work with young people...... at risk involves guidance to “the right path”, since individual guidance seems to be the key asset in mobilizing young person’s needs and experiences. The article indicates important elements in the guidance of youth at risk, such as psychological intervention and personal support, support from...

  12. EVALUATION OF ALTERNATIVE FILTER MEDIA FOR THE ROTARY MICROFILTER

    Energy Technology Data Exchange (ETDEWEB)

    Poirier, M.; Herman, D.; Bhave, R.

    2011-09-13

    SRS is currently developing and testing several processes to treat high level radioactive liquid waste. These processes include the Integrated Salt Disposition Process (ISDP), the Salt Waste Processing Facility (SWPF), and the Small Column Ion Exchange Process (SCIX). Each of these processes has a solid-liquid separation process that limits its throughput. SRNL researchers identified and tested the rotary microfilter as a technology to increase solid-liquid separation throughput. The testing showed significant improvement in filter flux with the rotary microfilter over the baseline crossflow filter (i.e., 2.5-6.5X during scoping tests, as much as 10X in actual waste tests, and approximately 3X in pilot-scale tests). SRNL received funding from DOE EM-21, and subsequently DOE EM-31 to develop the rotary microfilter for high level radioactive service. The work has included upgrading the rotary microfilter for radioactive service, testing with simulated SRS waste streams, and testing it with simulated Hanford waste streams. While the filtration rate is better than that obtained during testing of crossflow filters, the authors believe the rotary microfilter throughput can be improved by using a better filter membrane. The rotary microfilter membrane is made of stainless steel (Pall PMM050). Previous testing, funded by DOE EM-21, showed that asymmetric filters composed of a ceramic membrane on top of a stainless steel support produced higher filter flux than 100% stainless steel symmetric filters in crossflow filter tests. In that testing, the Pall Accusep and Graver filters produced 13-21% larger filter flux than the baseline 0.1 {micro}m Mott filter. While the improvement in flux is not as dramatic as the improvement of the rotary filter over a crossflow filter, a 13-21% increase could reduce the lifetime of a 30 year process by 4-6 years, with significant cost savings. Subsequent rotary filter testing showed the Pall PMM050 stainless steel filter membrane produced

  13. Anmeldelser

    Directory of Open Access Journals (Sweden)

    Mikkel Leth Jespersen

    2010-11-01

    Full Text Available Anmeldelser af:Erik Fischer, Michael Bøgh Rasmussen, Ernst Jonas Bencard: Melchior Lorck. Bd. 1-4. Forlaget Vandkunsten, 2009.Ulrik Langen: Den afmægtige – en biografi om Christian 7. Jyllands-Postens Forlag, 2008. 542 s., ill.Palle Thilo: Orlogsbriggen Lougen, 18 kanoner, 1791-1802.Forlaget Falcon, 2009. 169 s., ill.Kjeld Hansen: Det tabte land. Den store fortælling om magten over det danske landskab. Gads Forlag, 2008. 847 s., ill.Anette Faye Jacobsen: Husbondret. Rettighedskulturer i Danmark 1750-1920. Museum Tusculanums Forlag, 2008. 574 s.Poul Ulrich Jensen: Byens plan. Vejles fysiske udvikling 1786-2007. Vejles Historie bd. 5. Vejle Kommune, 2007. 250 s., ill.Gerda Bonderup, Jørgen Mikkelsen og Lisbeth Skjernov (red.: „af yderste Vigtighed for det hele Borgersamfunds Tryghed“. Medicinalberetninger og deres anvendelsesmuligheder i historisk forskning. Kildeskriftselskabet, 2005. 491 s.

  14. Polymeric Biodegradable Stent Insertion in the Esophagus

    Directory of Open Access Journals (Sweden)

    Kai Yang

    2016-04-01

    Full Text Available Esophageal stent insertion has been used as a well-accepted and effective alternative to manage and improve the quality of life for patients diagnosed with esophageal diseases and disorders. Current stents are either permanent or temporary and are fabricated from either metal or plastic. The partially covered self-expanding metal stent (SEMS has a firm anchoring effect and prevent stent migration, however, the hyperplastic tissue reaction cause stent restenosis and make it difficult to remove. A fully covered SEMS and self-expanding plastic stent (SEPS reduced reactive hyperplasia but has a high migration rate. The main advantage that polymeric biodegradable stents (BDSs have over metal or plastic stents is that removal is not require and reduce the need for repeated stent insertion. But the slightly lower radial force of BDS may be its main shortcoming and a post-implant problem. Thus, strengthening support of BDS is a content of the research in the future. BDSs are often temporarily effective in esophageal stricture to relieve dysphagia. In the future, it can be expect that biodegradable drug-eluting stents (DES will be available to treat benign esophageal stricture, perforations or leaks with additional use as palliative modalities for treating malignant esophageal stricture, as the bridge to surgery or to maintain luminal patency during neoadjuvant chemoradiation.

  15. On-line parallel reversed phase two-dimensional liquid chromatography for high-throughput analysis of complex proteomic samples

    Institute of Scientific and Technical Information of China (English)

    WANG Zhicong; ZHANG Qinghe; LI Tong; ZHAO Zhongyi; ZHANG Weibing

    2006-01-01

    A comprehensive two-dimensional liquid chromatographic system (2D SCX/RP) is constructed with a 10-port-2-way valve using strong cation exchange chromatography (Hypersil SCX, 100 mm×4.6 mm I.D.) followed by reversed phase chromatography (Hypersil BDS C18, 15 mm×4.6 mm I.D.) to separate the complex peptides from globin peptic hydrolysate. After the sample was loaded on the SCX column, the phosphate buffer (pH 4.0) was used to elute the peptides. Then, elutes flowed through the interface and the peptides focused on the head of the trapping columns (Hypersil BDS C18, 15 mm×4.6 mm I.D.) but salt passed into the waste. After the valve was switched, the samples were flushed with a backward flow into the RP analytical column. The peptides on the SCX were eluted with 12 discontinuous steps linearly increasing salt concentrations. The peptides enriched on the trapping column were desalted and separated by the RP columns. The resolution and the resolved peaks of the 2D SCX/RP system were greatly increased and the total peak capacity reached as high as 2280.

  16. Cognitive changes after carotid artery stenting

    Energy Technology Data Exchange (ETDEWEB)

    Grunwald, I.Q.; Politi, M.; Struffert, T.; Krick, C.; Backens, M. [University of the Saarland, Department for Diagnostic and Interventional Neuroradiology, Homburg (Germany); Supprian, T.; Falkai, P.; Reith, W. [University of the Saarland, Clinic for Psychiatry and Psychotherapy, Homburg (Germany)

    2006-05-15

    We aimed to test changes in cognitive performance after carotid artery stenting (CAS). Ten patients were neuropsychologically tested at least 24 h before and 48 h after CAS. To diminish thromboembolic events, we used a proximal protection device. The following neuropsychological tests were selected: The Mini Mental State Examination (MMSE), symbol digit test and subtests of the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) battery (verbal fluency, constructional practice, word list memory and delayed recall). Affective state was determined by the Beck Depression Score (BDS). No patient suffered from depression (BDS <1) or dementia (MMSE 29.9{+-}1.5). Nine of the ten patients (P=0.12) showed increased speed in the Number Connection Test (NCT) (corresponding to trail making test). Most patients showed better or similar results concerning delayed recall (P=0.31). No change was observed in the symbol digit test, word list memory, verbal fluency or constructional practice. Better results concerning NCT and delayed recall after carotid stenting might be due to improved brain perfusion. After CAS, cognitive and memory performance seem to improve. Further studies with different time intervals and more refined testing, as well as perfusion-weighted imaging, are needed. (orig.)

  17. Global Navigation Satellite System Multipath Mitigation Using a Wave-Absorbing Shield.

    Science.gov (United States)

    Yang, Haiyan; Yang, Xuhai; Sun, Baoqi; Su, Hang

    2016-08-22

    Code multipath is an unmanaged error source in precise global navigation satellite system (GNSS) observation processing that limits GNSS positioning accuracy. A new technique for mitigating multipath by installing a wave-absorbing shield is presented in this paper. The wave-absorbing shield was designed according to a GNSS requirement of received signals and collected measurements to achieve good performance. The wave-absorbing shield was installed at the KUN1 and SHA1 sites of the international GNSS Monitoring and Assessment System (iGMAS). Code and carrier phase measurements of three constellations were collected on the dates of the respective installations plus and minus one week. Experiments were performed in which the multipath of the measurements obtained at different elevations was mitigated to different extents after applying the wave-absorbing shield. The results of an analysis and comparison show that the multipath was mitigated by approximately 17%-36% on all available frequencies of BeiDou Navigation Satellite System (BDS), Global Positioning System (GPS), and Global Navigation Satellite System (GLONASS) satellites. The three-dimensional accuracies of BDS, GPS, and GLONASS single-point positioning (SPP) were, respectively, improved by 1.07, 0.63 and 0.49 m for the KUN1 site, and by 0.72, 0.79 and 0.73 m for the SHA1 site. Results indicate that the multipath of the original observations was mitigated by using the wave-absorbing shield.

  18. IRAS 16253-2429: the First Proto-Brown Dwarf Binary Candidate Identified through Dynamics of Jets

    CERN Document Server

    Hsieh, Tien-Hao; Belloche, Arnaud; Wyrowski, Friedrich

    2016-01-01

    The formation mechanism of brown dwarfs (BDs) is one of the long-standing problems in star formation because the typical Jeans mass in molecular clouds is too large to form these substellar objects. To answer this question, it is crucial to study a BD at the embedded phase. IRAS 16253-2429 is classified as a very low luminosity object (VeLLO) with internal luminosity 0.1 Lsun. VeLLOs are believed to be very low-mass protostars or even proto-BDs. We observed the jet/outflow driven by IRAS 16253-2429 in CO (2-1), (6-5), and (7-6) using the IRAM 30 m and APEX telescopes and the SMA in order to study its dynamical features and physical properties. Our SMA map reveals two protostellar jets, indicating the existence of a proto-binary system as implied by the precessing jet detected in H2 emission. We detect a wiggling pattern in the position-velocity diagrams along the jet axes, which is likely due to the binary orbital motion. Based on this, we derive the current mass of the binary as ~0.032 Msun. Given the low en...

  19. Uncovering the Outflow Driven by the Brown Dwarf LS-RCr A1: H-alpha as a Tracer of Outflow Activity in Brown Dwarfs

    CERN Document Server

    Whelan, E T; Bacciotti, F

    2009-01-01

    It is now apparent that classical T Tauri-like outflows commonly accompany the formation of young brown dwarfs. To date two optical outflows have been discovered and results presented in this paper increase this number to three. Using spectro-astrometry the origin of the LS-RCrA 1 forbidden emission lines in a blue-shifted outflow is confirmed. The non-detection of the red-shifted component of the outflow in forbidden lines, along with evidence for some separation between low and high velocity outflow components, do not support the hypothesis that LS-RCrA 1 has an edge-on accretion disk. The key result of this analysis is the discovery of an outflow component to the H-alpha line. The H-alpha line profile has blue and red-shifted features in the wings which spectro-astrometry reveals to also originate in the outflow. The discovery that H-alpha emission in BDs can have a significant contribution from an outflow suggests the use of H-alpha line widths as a proxy of mass accretion in BDs is not clear-cut. This me...

  20. Influence of adsorbed polar molecules on the electronic transport in a composite material Li(1.1)V3O8-PMMA for lithium batteries.

    Science.gov (United States)

    Badot, J C; Ligneel, E; Dubrunfaut, O; Gaubicher, J; Guyomard, D; Lestriez, B

    2012-07-14

    The broadband dielectric spectroscopy (BDS) technique (40 to 10(10) Hz) is used here to measure the electronic transport across all observed size scales of a Li(1.1)V(3)O(8)-polymer-gel composite material for lithium batteries. Different electrical relaxations are evidenced, resulting from the polarizations at the different scales of the architecture: (i) atomic lattice (small-polaron hopping), (ii) particles, (iii) clusters of particles, and finally (iv) sample-current collector interface. A very good agreement with dc-conductivity measurements on a single macro-crystal [M. Onoda and I. Amemiya, J. Phys.: Condens. Matter, 2003, 15, 3079.] shows that the BDS technique does allow probing the bulk (intrinsic) electrical properties of a material in the form of a network of particles separated by boundaries in a composite. Moreover, this study highlights a lowering of the surface electronic conductivity of Li(1.1)V(3)O(8) particles upon adsorption of polar ethylene carbonate (EC) and propylene carbonate (PC) that trap surface polarons. This result is meaningful as EC and PC are typical constituents of a liquid electrolyte of lithium batteries. It is thus suggested that interactions between active material particles and the liquid electrolyte play a role in the electronic transport within composite electrodes used in a lithium battery.

  1. High level expression of human epithelial β-defensins (hBD-1, 2 and 3 in papillomavirus induced lesions

    Directory of Open Access Journals (Sweden)

    Chong Kong T

    2006-09-01

    Full Text Available Abstract Background Epithelial defensins including human β-defensins (hBDs and α-defensins (HDs are antimicrobial peptides that play important roles in the mucosal defense system. However, the role of defensins in papillomavirus induced epithelial lesions is unknown. Results Papilloma tissues were prospectively collected from 15 patients with recurrent respiratory papillomatosis (RRP and analyzed for defensins and chemokine IL-8 expression by quantitative, reverse-transcriptase polymerase chain reaction (RT-PCR assays. HBD-1, -2 and -3 mRNAs were detectable in papilloma samples from all RRP patients and the levels were higher than in normal oral mucosal tissues from healthy individuals. Immunohistochemical analysis showed that both hBD-1 and 2 were localized in the upper epithelial layers of papilloma tissues. Expression of hBD-2 and hBD-3 appeared to be correlated as indicated by scatter plot analysis (r = 0.837, p Conclusion Human β-defensins are upregulated in respiratory papillomas. This novel finding suggests that hBDs might contribute to innate and adaptive immune responses targeted against papillomavirus-induced epithelial lesions.

  2. 中国证券市场非线性结构的实证检验%The Empirical Test for Nonlinear Structure of China's Stock Market

    Institute of Scientific and Technical Information of China (English)

    邹裔忠

    2012-01-01

    用BDS统计量进行实证检验,找到了我国证券市场对数收益率序列存在非线性结构的证据,并且通过稳定性分析和线性过滤后的BDS统计量检验,排除了由非平稳和线性依赖产生非线性结构的可能。说明我国证券市场的非线性结构类型只能是混沌或非线性随机过程。%Through the BDS statistical test, the author discovered the evidence of the non-linear structure in the logarithmic return series of the China's stock market. And through stability analysis and the BDS statistical test after filtered linear, the author ruled out that the non-stationary and linear dependence are cause of the nonlinear structure. It is shows that the type of nonlinear structure in China's securities market only can be the chaos or nonlinear stochastic processes.

  3. AB INITIO EQUATIONS OF STATE FOR HYDROGEN (H-REOS.3) AND HELIUM (He-REOS.3) AND THEIR IMPLICATIONS FOR THE INTERIOR OF BROWN DWARFS

    Energy Technology Data Exchange (ETDEWEB)

    Becker, Andreas; Lorenzen, Winfried; Schöttler, Manuel; Redmer, Ronald [Institut für Physik, Universität Rostock, D-18051 Rostock (Germany); Fortney, Jonathan J.; Nettelmann, Nadine [Department of Astronomy and Astrophysics, University of California, Santa Cruz, CA 95064 (United States)

    2015-01-01

    We present new equations of state (EOSs) for hydrogen and helium covering a wide range of temperatures from 60 K to 10{sup 7} K and densities from 10{sup –10} g cm{sup –3} to 10{sup 3} g cm{sup –3}. They include an extended set of ab initio EOS data for the strongly correlated quantum regime with an accurate connection to data derived from other approaches for the neighboring regions. We compare linear mixing isotherms based on our EOS tables with available real mixture data. A first important astrophysical application of this new EOS data is the calculation of interior models for Jupiter and comparison with recent results. Second, mass-radius relations are calculated for Brown Dwarfs (BDs) which we compare with predictions derived from the widely used EOS of Saumon, Chabrier, and van Horn. Furthermore, we calculate interior models for typical BDs with different masses, namely, Corot-3b, Gliese-229b, and Corot-15b, and the giant planet KOI-889b. The predictions for the central pressures and densities differ by up to 10% dependent on the EOS used. Our EOS tables are made available in the supplemental material of this paper.

  4. Genetic analysis of benzothiophene biodesulfurization pathway of Gordonia terrae strain C-6.

    Directory of Open Access Journals (Sweden)

    Wei Wang

    Full Text Available Sulfur can be removed from benzothiophene (BT by some bacteria without breaking carbon-carbon bonds. However, a clear mechanism for BT desulfurization and its genetic components have not been reported in literatures so far. In this study, we used comparative transcriptomics to study differential expression of genes in Gordonia terrae C-6 cultured with BT or sodium sulfate as the sole source of sulfur. We found that 135 genes were up-regulated with BT relative to sodium sulfate as the sole sulfur source. Many of these genes encode flavin-dependent monooxygenases, alkane sulfonate monooxygenases and desulfinase, which perform similar functions to those involved in the 4S pathway of dibenzothiophene (DBT biodesulfurization. Three of the genes were found to be located in the same operon, designated bdsABC. Cell extracts of pET28a-bdsABC transfected E. coli Rosetta (DE3 converted BT to a phenolic compound, identified as o-hydroxystyrene. These results advance our understanding of enzymes involved in the BT biodesulfurization pathway.

  5. Simultaneous Removal of Thiophene and Dibenzothiophene by Immobilized Pseudomonas delafieldii R-8 cells

    Institute of Scientific and Technical Information of China (English)

    唐煌; 李强; 王泽龙; 闫道江; 邢建民

    2012-01-01

    Biodesulfurization (BDS) is a promising technology for deep desulfurization. In this work, Pseudomonas delafieldii R-8 cells are immobilized in calcium alginate beads and used for BDS of transportation fuels. It is found that thiophene and dibenzothiophene (DBT) can be simultaneously metabolized by immobilized R-8 cells. The initial sulfur content in the model oil is 300 mg·kg-1 (thiophene " DI3T= 1 " 1). After 10 h of treatment, the thiophene concentration is reduced by 40%, while DBT is reduced by 25%. The utilization rate of thiophene is faster than that of DBT. Moreover, the oil/water ratio of alginate immobilized cells is studied to reduce the water volume in desulfurization systems. Long-term recycling of BDS by alginate immobilized cells is carried out with oil/water ratio at 5 : 1. The immobilized cells are successfully reused over 15 batch cycles. In the last batch, the desulfurization activity remains at least 75% of the first batch.

  6. Executive Summary of the Workshop on Polarization and Beam Energy Measurements at the ILC

    Energy Technology Data Exchange (ETDEWEB)

    Aurand, B.; Bailey, I.; Bartels, C.; Blair, G.; Brachmann, A.; Clarke, J.; Deacon, L.; Duginov, V.; Ghalumyan, A.; Hartin, A.; Hauptman, J.; Helebrant, C.; Hesselbach, S.; Kafer, D.; List, J.; Lorenzon, W.; Lyapin, A.; Marchesini, I.; Melikian, R.; Monig, K.; Moeit, K.C.; /Bonn U. /Cockcroft Inst. Accel. Sci. Tech. /DESY /DESY, Zeuthen /Royal Holloway, U. of London /SLAC /Daresbury /Dubna, JINR /Yerevan Phys. Inst /Oxford U., JAI /Iowa State U. /Durham U., IPPP /Michigan U. /University Coll. London /Novosibirsk, IYF /Minsk, Inst. Phys. /Oregon U.

    2008-07-25

    This note summarizes the results of the 'Workshop on Polarization and Beam Energy Measurements at the ILC', held at DESY (Zeuthen) April 9-11 2008. The topics for the workshop included (1) physics requirements, (2) polarized sources and low energy polarimetry, (3) BDS polarimeters, (4) BDS energy spectrometers, and (5) physics-based measurements of beam polarization and beam energy from collider data. Discussions focused on the current ILC baseline program as described in the Reference Design Report (RDR), which includes physics runs at beam energies between 100 and 250 GeV, as well as calibration runs on the Z-pole. Electron polarization of P{sub e{sup -}} {approx}> 80% and positron polarization of P{sub e{sup +}} {approx}> 30% are part of the baseline configuration of the machine. Energy and polarization measurements for ILC options beyond the baseline, including Z-pole running and the 1 TeV energy upgrade, were also discussed.

  7. The spectrum of borderline personality disorder: a neurophysiological view.

    Science.gov (United States)

    Stone, Michael H

    2014-01-01

    Borderline Personality Disorder (BPD) has been defined as a personality disorder in all editions of DSM since 1980; namely, DSM III through V. The criteria are a mixture of symptoms and traits; the etiology, a heterogeneous array of genetic, constitutional, and environmental factors. Until recently the diagnosis relied on clinical descriptions. In the last two decades, neurophysiological data, including MRI and fMRI, have established correlates in various brain regions, particularly those involving the frontal lobes and various limbic structures, that show promise of providing a more substantial basis for diagnosis-relying primarily on (internal) brain changes, rather than on (external) clinical observation. Some of the changes in BPD consist of decreased volume in the orbitofrontal and dorsolateral prefrontal cortices and smaller volume in both the amygdala and hippocampus, though with heightened reactivity in the amygdala. Similar abnormalities have been noted in bipolar disorders (BDs) and in ADHD, both of which often accompany BPD and share certain clinical features. Persons with strong genetic predisposition to BDs can develop BPD even in the absence of adverse environmental factors; those with extreme adverse environmental factors (chiefly, early sexual molestation) can develop BPD in the absence of bipolar vulnerability. In some BPD patients, both sets of factors are present. As ideal treatment depends on careful analysis of these factors, neurophysiological testing may permit both more rational, brain-based diagnostic decisions and more appropriate therapeutic strategies.

  8. VizieR Online Data Catalog: Hydrogen and Helium EOS in brown dwarfs (Becker+, 2014)

    Science.gov (United States)

    Becker, A.; Lorenzen, W.; Fortney, J. J.; Nettelmann, N.; Schottler, M.; Redmer, R.

    2015-02-01

    We present new equations of state (EOSs) for hydrogen and helium covering a wide range of temperatures from 60K to 107K and densities from 10-10g/cm3 to 103g/cm3. They include an extended set of ab initio EOS data for the strongly correlated quantum regime with an accurate connection to data derived from other approaches for the neighboring regions. We compare linear mixing isotherms based on our EOS tables with available real mixture data. A first important astrophysical application of this new EOS data is the calculation of interior models for Jupiter and comparison with recent results. Second, mass-radius relations are calculated for Brown Dwarfs (BDs) which we compare with predictions derived from the widely used EOS of Saumon, Chabrier, and van Horn. Furthermore, we calculate interior models for typical BDs with different masses, namely, Corot-3b, Gliese-229b, and Corot-15b, and the giant planet KOI-889b. The predictions for the central pressures and densities differ by up to 10% dependent on the EOS used. (2 data files).

  9. Global Navigation Satellite System Multipath Mitigation Using a Wave-Absorbing Shield

    Directory of Open Access Journals (Sweden)

    Haiyan Yang

    2016-08-01

    Full Text Available Code multipath is an unmanaged error source in precise global navigation satellite system (GNSS observation processing that limits GNSS positioning accuracy. A new technique for mitigating multipath by installing a wave-absorbing shield is presented in this paper. The wave-absorbing shield was designed according to a GNSS requirement of received signals and collected measurements to achieve good performance. The wave-absorbing shield was installed at the KUN1 and SHA1 sites of the international GNSS Monitoring and Assessment System (iGMAS. Code and carrier phase measurements of three constellations were collected on the dates of the respective installations plus and minus one week. Experiments were performed in which the multipath of the measurements obtained at different elevations was mitigated to different extents after applying the wave-absorbing shield. The results of an analysis and comparison show that the multipath was mitigated by approximately 17%–36% on all available frequencies of BeiDou Navigation Satellite System (BDS, Global Positioning System (GPS, and Global Navigation Satellite System (GLONASS satellites. The three-dimensional accuracies of BDS, GPS, and GLONASS single-point positioning (SPP were, respectively, improved by 1.07, 0.63 and 0.49 m for the KUN1 site, and by 0.72, 0.79 and 0.73 m for the SHA1 site. Results indicate that the multipath of the original observations was mitigated by using the wave-absorbing shield.

  10. Global Navigation Satellite System Multipath Mitigation Using a Wave-Absorbing Shield.

    Science.gov (United States)

    Yang, Haiyan; Yang, Xuhai; Sun, Baoqi; Su, Hang

    2016-01-01

    Code multipath is an unmanaged error source in precise global navigation satellite system (GNSS) observation processing that limits GNSS positioning accuracy. A new technique for mitigating multipath by installing a wave-absorbing shield is presented in this paper. The wave-absorbing shield was designed according to a GNSS requirement of received signals and collected measurements to achieve good performance. The wave-absorbing shield was installed at the KUN1 and SHA1 sites of the international GNSS Monitoring and Assessment System (iGMAS). Code and carrier phase measurements of three constellations were collected on the dates of the respective installations plus and minus one week. Experiments were performed in which the multipath of the measurements obtained at different elevations was mitigated to different extents after applying the wave-absorbing shield. The results of an analysis and comparison show that the multipath was mitigated by approximately 17%-36% on all available frequencies of BeiDou Navigation Satellite System (BDS), Global Positioning System (GPS), and Global Navigation Satellite System (GLONASS) satellites. The three-dimensional accuracies of BDS, GPS, and GLONASS single-point positioning (SPP) were, respectively, improved by 1.07, 0.63 and 0.49 m for the KUN1 site, and by 0.72, 0.79 and 0.73 m for the SHA1 site. Results indicate that the multipath of the original observations was mitigated by using the wave-absorbing shield. PMID:27556466

  11. Instantaneous Real-Time Kinematic Decimeter-Level Positioning with BeiDou Triple-Frequency Signals over Medium Baselines

    Directory of Open Access Journals (Sweden)

    Xiyang He

    2015-12-01

    Full Text Available Many applications, such as marine navigation, land vehicles location, etc., require real time precise positioning under medium or long baseline conditions. In this contribution, we develop a model of real-time kinematic decimeter-level positioning with BeiDou Navigation Satellite System (BDS triple-frequency signals over medium distances. The ambiguities of two extra-wide-lane (EWL combinations are fixed first, and then a wide lane (WL combination is reformed based on the two EWL combinations for positioning. Theoretical analysis and empirical analysis is given of the ambiguity fixing rate and the positioning accuracy of the presented method. The results indicate that the ambiguity fixing rate can be up to more than 98% when using BDS medium baseline observations, which is much higher than that of dual-frequency Hatch-Melbourne-Wübbena (HMW method. As for positioning accuracy, decimeter level accuracy can be achieved with this method, which is comparable to that of carrier-smoothed code differential positioning method. Signal interruption simulation experiment indicates that the proposed method can realize fast high-precision positioning whereas the carrier-smoothed code differential positioning method needs several hundreds of seconds for obtaining high precision results. We can conclude that a relatively high accuracy and high fixing rate can be achieved for triple-frequency WL method with single-epoch observations, displaying significant advantage comparing to traditional carrier-smoothed code differential positioning method.

  12. A Pulsation Search Among Young Brown Dwarfs and Very Low Mass Stars

    CERN Document Server

    Cody, Ann Marie

    2014-01-01

    In 2005, Palla & Baraffe proposed that brown dwarfs (BDs) and very low mass stars (VLMSs; <0.1 solar masses) may be unstable to radial oscillations during the pre-main-sequence deuterium burning phase. With associated periods of 1-4 hours, this potentially new class of pulsation offers unprecedented opportunities to probe the interiors and evolution of low-mass objects in the 1-15 million year age range. Following up on reports of short-period variability in young clusters, we designed a high-cadence photometric monitoring campaign to search for deuterium-burning pulsation among a sample of 348 BDs and VLMSs in the four young clusters $\\sigma$ Orionis, Chamaeleon I, IC 348, and Upper Scorpius. In the resulting light curves we achieved sensitivity to periodic signals of amplitude several millimagnitudes, on timescales from 15 minutes to two weeks. Despite the exquisite data quality, we failed to detect any periodicities below seven hours. We conclude that D-burning pulsations are not able to grow to obs...

  13. Preconceptional Iron Intake and Gestational Diabetes Mellitus

    Science.gov (United States)

    Darling, Anne Marie; Mitchell, Allen A.; Werler, Martha M.

    2016-01-01

    Our objective was to assess the impact of preconceptional heme and non-heme iron on gestational diabetes mellitius (GDM) in the Boston University Slone Epidemiology Birth Defects Study (BDS). This retrospective cohort analysis included 7229 participants enrolled in the BDS between 1998 and 2008 who gave birth to non-malformed infants and were free of pre-existing diabetes. All data were collected through structured interviews conducted within 6 months of delivery. Calorie-adjusted and multivariable odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using logistic regression models. Preconceptional dietary heme iron was modestly associated with an elevated risk of GDM among those (multivariable OR comparing the fifth quintile to the first: 1.55; 95% CI 0.98, 2.46). Conversely, preconceptional dietary non-heme iron was associated with a decreased risk of GDM among those in the fifth quintile of intake compared to the first (multivariable OR: 0.48; 95% CI 0.28, 0.81). Women who consumed supplemental iron during preconception also had a decreased risk of GDM (multivariable OR: 0.78; 95% CI 0.60, 1.02). In conclusion, our data support a positive association between preconceptional heme iron intake and GDM and an inverse association between preconceptional non-heme iron intake from foods and preconceptional intake from supplements. PMID:27231921

  14. Noise Reduction Analysis of Radar Rainfall Using Chaotic Dynamics and Filtering Techniques

    Directory of Open Access Journals (Sweden)

    Soojun Kim

    2014-01-01

    Full Text Available The aim of this study is to evaluate the filtering techniques which can remove the noise involved in the time series. For this, Logistic series which is chaotic series and radar rainfall series are used for the evaluation of low-pass filter (LF and Kalman filter (KF. The noise is added to Logistic series by considering noise level and the noise added series is filtered by LF and KF for the noise reduction. The analysis for the evaluation of LF and KF techniques is performed by the correlation coefficient, standard error, the attractor, and the BDS statistic from chaos theory. The analysis result for Logistic series clearly showed that KF is better tool than LF for removing the noise. Also, we used the radar rainfall series for evaluating the noise reduction capabilities of LF and KF. In this case, it was difficult to distinguish which filtering technique is better way for noise reduction when the typical statistics such as correlation coefficient and standard error were used. However, when the attractor and the BDS statistic were used for evaluating LF and KF, we could clearly identify that KF is better than LF.

  15. Micropropagation of onion (Allium cepa L.) from immature inflorescences.

    Science.gov (United States)

    Marinangeli, Pablo

    2013-01-01

    In vitro plant production by direct organogenesis from immature flower heads is an ideal approach for clonal propagation of onions (Allium cepa L.). This technique ensures genetic stability, high propagation rate, and maintains donor plant of explants with an advantage over other means of in vitro regeneration. Onion micropropagation is usually applied in breeding programs, maintenance, and multiplication of cytoplasmic-male sterile lines for hybrid production, germplasm conservation, and as a tool for the application of other biotechnologies. For in vitro culture, mature onion bulbs are induced to reproductive phase by vernalization and forced to inflorescence initiation. Immature umbels are dissected from bulbs or cut directly when they appear from the pseudostem among the leaves. Disinfected inflorescences are cultivated in BDS basal medium supplemented with 30 g/L sucrose, 0.1 mg/L naphthalene acetic acid, 1 mg/L N (6)-benzyladenine, and 8 g/L agar, pH 5.5, under 16 h photoperiod white fluorescent light (PPD: 50-70 μmol/m(2)s) for 35 days. The regenerated shoot clumps are divided and subculture under the same conditions. For bulbification phase, the individual shoots are cultured in BDS basal medium containing 90 g/L sucrose, without plant growth regulators, pH 5.5, under 16 h photoperiod. Microbulbs can be directly cultivated ex vitro without acclimation. PMID:23179710

  16. Cognitive changes after carotid artery stenting

    International Nuclear Information System (INIS)

    We aimed to test changes in cognitive performance after carotid artery stenting (CAS). Ten patients were neuropsychologically tested at least 24 h before and 48 h after CAS. To diminish thromboembolic events, we used a proximal protection device. The following neuropsychological tests were selected: The Mini Mental State Examination (MMSE), symbol digit test and subtests of the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) battery (verbal fluency, constructional practice, word list memory and delayed recall). Affective state was determined by the Beck Depression Score (BDS). No patient suffered from depression (BDS <1) or dementia (MMSE 29.9±1.5). Nine of the ten patients (P=0.12) showed increased speed in the Number Connection Test (NCT) (corresponding to trail making test). Most patients showed better or similar results concerning delayed recall (P=0.31). No change was observed in the symbol digit test, word list memory, verbal fluency or constructional practice. Better results concerning NCT and delayed recall after carotid stenting might be due to improved brain perfusion. After CAS, cognitive and memory performance seem to improve. Further studies with different time intervals and more refined testing, as well as perfusion-weighted imaging, are needed. (orig.)

  17. The influence of different types of satellite exiting in system RAIM performance in BeiDou Satellite Navigation System

    Science.gov (United States)

    Wang, Shi-tai; Peng, Jun-huan

    2015-12-01

    The space constellation of BeiDou Navigation Satellite System(BDS)has three main components, Geostationary Earth Orbits (GEOs), Medium Earth Orbits (MEOs) and Inclined Geosynchronous Satellite Orbits(IGSOs).This paper selected 6 satellite respectively in three types to simulate their exiting service, and used the statistical methods to assess receiver autonomous integrity monitoring RAIM availability and fault detection FD capability of BeiDou14 Phase with 14 satellites under the circumstances. This paper assessed RAIM availability performance from satellites and constellation geometry configuration by the number of visible satellites (NVS, NVS>~5) and position dilution of precision (PDOP, PDOPMDE). The analyses of simulation results testify that the exiting of single MEO or IGSO satellite have no obvious effect on RAIM availability and error detection ability. However GEO satellite's exiting can make the number of points in where the constellation geometry is not available and maximum minimum detectable deviation and maximum minimum detectable influence significantly increase. Relative to other two satellites, GEO satellites' health have a significant impact on the RAIM performance of BDS.

  18. Management of bipolar disorders in women by nonpharmacological methods.

    Science.gov (United States)

    Naik, Sujit Kumar

    2015-07-01

    Several reasons justify the need for nonpharmacological interventions for bipolar disorder (BD) in women. This review focuses on psychosocial therapies for BDs in women. The research evidence for a wide range of psychosocial interventions for the management of BDs in women has been presented. All the interventions have some common components like targeting disease management, information regarding illness, and coping skills. There also are distinctive features like cognitive restructuring and self-rated mood charts in cognitive behavior therapy, regulation of sleep/wake cycles and daily routines in interpersonal sleep regulation therapy, and communication skill training in family treatments. Many psychosocial interventions hold promise as adjunctive therapies for bipolar patients. In India, there is a considerable dearth of literature in this area due lack of skilled staff for psychosocial interventions. Future trials need to: Clarify which populations are most likely to benefit from which strategies; identify putative mechanisms of action; systematically evaluate costs, benefits, and generalizability of effects, and record adverse effects. PMID:26330644

  19. Hints for new sources of flavour violation in meson mixing

    CERN Document Server

    Blanke, Monika

    2016-01-01

    The recent results by the Fermilab Lattice and MILC collaborations on the hadronic matrix elements entering $B_{d,s}-\\bar B_{d,s}$ mixing show a significant tension of the measured values of the mass differences $\\Delta M_{d,s}$ with their SM predictions. We review the implications of these results in the context of Constrained Minimal Flavour Violation models. In these models, the CKM elements $\\gamma$ and $|V_{ub}|/|V_{cb}|$ can be determined from $B_{d,s}-\\bar B_{d,s}$ mixing observables, yielding a prediction for $\\gamma$ below its tree-level value. Determining subsequently $|V_{cb}|$ from the measured value of either $\\Delta M_s$ or $\\varepsilon_K$ gives inconsistent results, with the tension being smallest in the Standard Model limit. This tension can be resolved if the flavour universality of new contributions to $\\Delta F = 2$ observables is broken. We briefly discuss the case of $U(2)^3$ flavour models as an illustrative example.

  20. Epithermal Neutron Activation Analysis of the Asian Herbal Plants

    International Nuclear Information System (INIS)

    Asian medicinal herbs Chrysanthemum (Spiraea aquilegifolia Pall.) and Red Sandalwood (Pterocarpus Santalinus) are widely used in folk and Ayurvedic medicine for healing and preventing some diseases. The modern medical science has proved that the Chrysanthemum (Spiraea aquilegifolia Pall.) possesses the following functions: reducing blood press, dispelling cancer cell, coronary artery's expanding and bacteriostating and Red Sandalwood (Pterocarpus Santalinus) is recommended against headache, toothache, skin diseases, vomiting and sometimes it is taken for treatment of diabetes. Species of Chrysanthemums were collected in the north-eastern and central Mongolia, and the Red Sandalwood powder was imported from India. Samples of Chrysanthemums (branches, flowers and leaves)(0.5 g) and red sandalwood powder (0.5 g) were subjected to the multi-element instrumental neutron activation analysis using epithermal neutrons (ENAA) at the IBR-2 reactor, Frank Laboratory of Neutron Physics (FLNP) JINR, Dubna. A total of 41 elements (Na, Mg, Al, Cl, K, Ca, Sc, V, Cr, Mn, Fe, Co, Ni, Zn, As, Se, Br, Rb, Sr, Zr, Mo, Cd, Cs, Ba, La, Hf, Ta, W, Sb, Au, Hg, Ce, Nd, Sm, Eu, Tb, Dy, Yb, Th, U, Lu) were determined. For the first time such a large group of elements was determined in the herbal plants used in Mongolia. The quality control of the analytical results was provided by using certified reference material Bowen Cabbage. The results obtained are compared to the ''Reference plant? data (B. Markert, 1992) and interpreted in terms of excess of such elements as Se, Cr, Ca, Fe, Ni, Mo, and rare earth elements.

  1. Is the air handling capability of the quadrox D pump dependent within an ECMO circuit? An in vitro study.

    Science.gov (United States)

    Gill, Martin C; Dando, Hayden; John, Dittmer

    2010-09-01

    The occurrence of gaseous microemboli (GME) within the extracorporeal membrane oxygenation circuit is largely overlooked, as are methods to ameliorate this occurrence. We aimed to determine if the air handling capability of the Quadrox D oxygenator was dependent upon whether it was used in conjunction with a centrifugal or roller pump; and if application of a Pall air eliminating filter (AEF) would prevent circuit air introduction from intravenous infusions. Using a blood primed circuit 1 mL of air was infused pre pump. GME were quantified post pump and post oxygenator using the EDAC Quantifier. Trials were conducted at 1 and 2 L/min flow. To prevent GME recirculation a Capiox SX18 was used in circuit with negative pressure applied to its oxygenator; an EDAC cuvette distal to this device quantified GME recirculation. Following air infusion, 3-5 minute data recordings were carried out for each trial. Separate trials were carried out for centrifugal and roller pumps, and for each flow rate. The process was then repeated following the application of the AEF to the air infusion line. More GME were detected post Quadrox D when the centrifugal pump was used in comparison to the roller pump at 1 L/min (p < .05), and 2 L/min (p = .05). A greater volume of air was detected post Quadrox D when used in conjunction with the centrifugal device at 1 L/min (p < or = .05), and 2 L/min (p < or = .05). Application of the AEF resulted in zero GME detected at any circuit location. The results of this study confirm that a greater total count and volume of GME are detected distal to the Quadrox D when used in conjunction with a Rotaflow centrifugal pump. Application of a Pall AEF to infusion and drug lines can prevent air introduction from this source.

  2. Epithermal Neutron Activation Analysis of the Asian Herbal Plants

    Science.gov (United States)

    Baljinnyam, N.; Jugder, B.; Norov, N.; Frontasyeva, M. V.; Ostrovnaya, T. M.; Pavlov, S. S.

    2011-06-01

    Asian medicinal herbs Chrysanthemum (Spiraea aquilegifolia Pall.) and Red Sandalwood (Pterocarpus Santalinus) are widely used in folk and Ayurvedic medicine for healing and preventing some diseases. The modern medical science has proved that the Chrysanthemum (Spiraea aquilegifolia Pall.) possesses the following functions: reducing blood press, dispelling cancer cell, coronary artery's expanding and bacteriostating and Red Sandalwood (Pterocarpus Santalinus) is recommended against headache, toothache, skin diseases, vomiting and sometimes it is taken for treatment of diabetes. Species of Chrysanthemums were collected in the north-eastern and central Mongolia, and the Red Sandalwood powder was imported from India. Samples of Chrysanthemums (branches, flowers and leaves) (0.5 g) and red sandalwood powder (0.5 g) were subjected to the multi-element instrumental neutron activation analysis using epithermal neutrons (ENAA) at the IBR-2 reactor, Frank Laboratory of Neutron Physics (FLNP) JINR, Dubna. A total of 41 elements (Na, Mg, Al, Cl, K, Ca, Sc, V, Cr, Mn, Fe, Co, Ni, Zn, As, Se, Br, Rb, Sr, Zr, Mo, Cd, Cs, Ba, La, Hf, Ta, W, Sb, Au, Hg, Ce, Nd, Sm, Eu, Tb, Dy, Yb, Th, U, Lu) were determined. For the first time such a large group of elements was determined in the herbal plants used in Mongolia. The quality control of the analytical results was provided by using certified reference material Bowen Cabbage. The results obtained are compared to the "Reference plant» data (B. Markert, 1992) and interpreted in terms of excess of such elements as Se, Cr, Ca, Fe, Ni, Mo, and rare earth elements.

  3. Clustering Analysis of Karyotype Resemblance-near Coefficient for 16 Species of Caragana Fabr.%16种锦鸡儿属植物核型似近系数聚类分析

    Institute of Scientific and Technical Information of China (English)

    宋芸; 乔永刚; 李祎; 吴玉香

    2011-01-01

    应用核型似近系数聚类分析方法研究我国16种锦鸡儿属植物的亲缘关系,并计算物种间的核型进化距离.结果表明:刺叶锦鸡儿(Caragana acanthophylla Kom.)与甘蒙锦鸡儿(C.opulens Kom.)间核型似近系数最大(0.9979),核型进化距离最小(0.0177),亲缘关系最近;青海锦鸡儿(C.chinghaiensis Liou f.)与中亚锦鸡儿[C.tragacanthoides (Pall.) Poir.]间核型似近系数最小(0.3127),核型进化距离最大(1.1625),亲缘关系最远;核型分类结果与形态学分类结果并不相符.%The genetic relationships among 16 species of Caragana were studied using karyotype resemblance-near coefficient and evolutionary distance among species was counted. The results showed that there were the biggest karyotype resemblance-near coefficient (X = 0. 9979) and the smallest evolutionary distance (De=0. 0177) between C. Acanthophylla Kom. And C. Opulens Kom. , indicating the closest relationship, and there was the minimum karyotype resemblance-near coefficient (X = 0. 3127) and the maximum evolutionary distance (De = 1. 1625) between C. Chinghaiensis Liou f. And C. Tragacanthoid.es (Pall. ) Poir. , indicating the most wide relationship. The results of clustering analysis did not accord with the phylogeny based on the morphology of these species. Results of this research have some scientific value in some study domains of this genus, such as resources utilization, taxonomy, and phylogeny.

  4. Clinical Evaluation of Acupuncture company with Oxiracetam in Treatment of Patients with Mild to Medium Vascular Dementia%针刺配合奥拉西坦胶囊治疗轻中度血管性痴呆的临床疗效观察

    Institute of Scientific and Technical Information of China (English)

    袁盈; 陈枫; 刘涵; 赵丽红

    2011-01-01

    目的 观察针刺配合奥拉西坦胶囊治疗轻中度血管性痴呆的临床疗效.方法 将76例轻中度血管性痴呆患者进行了临床随机对照前瞻性研究,其中38例为治疗组,采用针刺配合奥拉西坦胶囊治疗;38例为对照组,采用针刺配合尼莫地平片治疗.于治疗用药前、后第12周和第24周采用简易精神状态检查(MMSE)和Blessed - Roth痴呆量表(BDS)评定患者的认知功能、社会活动功能及日常生活能力.结果 治疗24周后,治疗组MMSE得分23.73±2.53高于对照组MMSE得分19.73±3.66;治疗组BDS得分7.12±5.07低于对照组BDS得分9.43±4.64.治疗组总有效率为86.84%,对照组总有效率为76.32%.结论 针刺配合奥拉西坦胶囊的中西医结合治疗方法,对轻中度VD患者智力状态和生活能力有明显的改善.%Objective To evaluate the effect of acupuncture company with oxiracetam in treatment of patients with mild to medium vascular dementia ( VD). Methods 76 patients with mild to medium VD were randomized by double blindness into 2 group. MMSE and BDS were employed to evaluate the effect. The subjects in the experimental group and the control were treated by acupuncture and orally administrated with oxiracetam and nimodipine respectively. Results After 24w of treatment, the MMSE scale is 23. 73 ±2. 53 to 23. 73 ±3. 66; the BDS scale is 7. 12 ±5. 07 to 9. 43 ±4. 64. The total efficient of the two group is separately 88. 84% and 76. 32%. Conclusion Acupuncture company with Oxiracetam show significant efficiency in treating mild to medium VD. It can be used extensively in clinic.

  5. Chaotic Properties of the Philippine Stock Exchange Index Returns

    Directory of Open Access Journals (Sweden)

    Jo-Hui Chen

    2015-03-01

    Full Text Available This study found evidences of chaos in the Philippine Stock Exchange Index (PSEi returns using three tests of chaotic behavior. The BDS test found that PSEi returns and ARMA residuals are not stochastic processes. With regards to the efficient market hypothesis (EMH, this paper cannot conclude the iid properties of GARCH residuals, except for the period of the Subprime Mortgage Crisis. The rescaled range (R/S analysis showed that most Hurst exponents of the PSEi returns, ARMA and GARCH residuals have chaotic tendencies and have trend-reinforcing series, but showed anti-persistence during crisis. Furthermore, the correlation dimension analyses supplemented the first two initial tests and showed that the correlation dimension does not converge to a stable value as the embedding dimension increases. Both values increased in relation with each other, further confirming that PSEi returns, ARMA and GARCH residuals are consistent with chaos.

  6. Biological Threats Detection Technologies

    International Nuclear Information System (INIS)

    Among many decisive factors, which can have the influence on the possibility of decreases the results of use biological agents should be mentioned obligatory: rapid detection and identification of biological factor used, the proper preventive treatment and the medical management. The aims of identification: to identify the factor used, to estimate the area of contamination, to evaluate the possible countermeasure efforts (antibiotics, disinfectants) and to assess the effectiveness of the decontamination efforts (decontamination of the persons, equipment, buildings, environment etc.). The objects of identification are: bacteria and bacteria's spores, viruses, toxins and genetically modified factors. The present technologies are divided into: based on PCR techniques (ABI PRISM, APSIS, BIOVERIS, RAPID), immuno (BADD, RAMP, SMART) PCR and immuno techniques (APDS, LUMINEX) and others (BDS2, LUNASCAN, MALDI). The selected technologies assigned to field conditions, mobile and stationary laboratories will be presented.(author)

  7. Investigation into biological nutrient removal from wastewater

    OpenAIRE

    Vabolienė, Giedrė; Matuzevičius, Algirdas Bronislovas

    2005-01-01

    Siekiant išvengti eutrofizacijos vandens telkiniuose, išleidžiant valytas nuotekas į uždarus ar mažai pratekančius vandens telkinius bei pakartotinai jas panaudojant kaip technologinį vandenį, būtina šalinti azotą ir fosforą. Viena iš naujausių azoto ir fosforo šalinimo technologijų – „BioBalance“ technologija pritaikyta Utenos miesto nuotekų valymo įrenginiuose. Šalinant fosforą biologiniu būdu didelės įtakos turi valomų nuotekų sudėtis, ypač svarbu žinoti BDS7/BP santykį nuotekose po mechan...

  8. Stability-indicating RP-HPLC method for simultaneous determination of gatifloxacin and flurbiprofen in binary combination

    Directory of Open Access Journals (Sweden)

    Islam Ullah Khan

    2014-04-01

    Full Text Available A stability-indicating RP-HPLC method is presented for determination of gatifloxacin and flurbiprofen in binary combination. Gatifloxacin, flurbiprofen and their degradation products were detected at 254 nm using a BDS Hypersil C8 (250 X 4.6 mm, 5 µm column and mixture of 20 mM phosphate buffer (pH 3.0 and methanol 30:70 v/v as mobile phase. Response was linear over the range of 15-105 mg mL-1 for gatifloxacin (r² > 0.998 and of 1.5-10.5 mg mL-1 for flurbiprofen (r² > 0.999. The developed method efficiently separated the analytical peaks from degradation products (peak purity index > 0.9999. The method developed can be applied successfully for determination of gatifloxacin and flurbiprofen in human serum, urine, pharmaceutical formulations, and their stability studies.

  9. Application of Modular Technology of Tightly-coupled GPS/INS%GPS/INS深组合技术及其应用

    Institute of Scientific and Technical Information of China (English)

    周坤芳; 任卓谊

    2016-01-01

    分析GPS/INS深组合结构,研究INS信息辅助GPS接收机基带环路技术,仿真研究GPS/INS深组合模式特性,其具有提高接收机动态适应能力、抗干扰能力、伪距测量精度等特性,拓展了卫星导航的应用范围.随着BDS具备亚太区域导航能力,鉴借GPS/INS深组合技术,分析BDS/INS深组合中的若干技术问题,以供相关人士研究参考.

  10. BFKL Pomeron and Bern-Dixon-Smirnov amplitudes in N=4 SUSY

    Energy Technology Data Exchange (ETDEWEB)

    Lipatov, L.N. [Petersburg Nuclear Physics Institute (Russian Federation)]|[Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik

    2008-10-15

    We review the theoretical approaches for investigations of the high energy hadron-hadron scattering in the Regge kinematics. It is demonstrated, that the gluon in QCD is reggeized and the Pomeron is a composite state of the reggeized gluons. Remarkable properties of the BFKL equation for the Pomeron wave function in QCD and supersymmetric gauge theories are outlined. Due to the AdS/CFT correspondence the BFKL Pomeron is equivalent to the reggeized graviton in the extended N=4 SUSY. The properties of the maximal transcendentality and integrability are realized in this model. The BDS multi-gluon scattering amplitudes are investigated in the Regge limit. They do not contain the Mandelstam cuts and are not valid beyond one loop. It is shown, that the hamiltonian for these composite states coincides with the hamiltonian of an integrable open Heisenberg spin chain. (orig.)

  11. High performance liquid chromatography with immobilized Ru(bpy)32+-KMn04 chemiluminescence detection and its application in metabolism of repaglinide in pig liver microsomes

    Institute of Scientific and Technical Information of China (English)

    Ai Hua Fu; Zhu Jun Zhang; Li Li Chen; Xiao Ming Zhang; Pan Xue

    2011-01-01

    A novel high performance liquid chromatography-chemiluminescence (HPLC-CL) method for investigation of in vitro metabolism of repaglinide in pig liver microsomes with microdialysis sampling technique was developed. The chromatographic separation was performed on a Hypersil BDS-C18 column with an isocratic mobile phase consisting of methanol and 0.01 mol/L KH2PO4 (pH 3.0) (volume ratio 75:25) at a flow rate of 1.0 mL/min. The detection was based on the chemiluminescence reaction of repaglinide with acidic potassium permanganate (KMnO4) and tris (2,2'-bipyridyl)ruthenium(III) (Ru(bpy)33+), which was immobilized on the cationic ion-exchange resin for obtaining high sensitivity and reducing consumption of expensive reagent.

  12. Optimization of nicotinamide and riboflavin in the biodesulfurization of dibenzothiophene using response surface methodology

    Directory of Open Access Journals (Sweden)

    Hossein Saber

    2013-01-01

    Full Text Available Introduction: Dibenzothiophene (DBT is a sulfuric compound and resistant to Hydrodesulfurization process.Rhodococcuserythropolis R1, a previously isolated bacterial strain, is capable to bioconversion of DBT to 2-hydroxybiphenyl (2-HBP.Materials and methods: The effect of nicotinamide (precursor of NAD and riboflavin (precursor of FMN on DBT biodesulfurization and growth rate by this strain was studied using Gibbs assay and turbidimeteric assay respectively. The level of cofactor precursors were optimized using response surface methodology (RSM. Results: Analyses showed that both nicotinamide and riboflavin were statistically significant and could enhance the biodesulfurization rate of DBT by induction of dsz operon. The optimum level of nicotinamide and riboflavin was obtained at 10.67 mM and 34.2 µM respectively. Discussion and conclusion: In spite of increasing in BDS, the addition of these cofactor precursors led to decreased growth rate and biomass production due to limitated effect of produced 2-HBP.

  13. Catalytic conversion of xylose and corn stalk into furfural over carbon solid acid catalyst in γ-valerolactone.

    Science.gov (United States)

    Zhang, Tingwei; Li, Wenzhi; Xu, Zhiping; Liu, Qiyu; Ma, Qiaozhi; Jameel, Hasan; Chang, Hou-min; Ma, Longlong

    2016-06-01

    A novel carbon solid acid catalyst was synthesized by the sulfonation of carbonaceous material which was prepared by carbonization of sucrose using 4-BDS as a sulfonating agent. TEM, N2 adsorption-desorption, elemental analysis, XPS and FT-IR were used to characterize the catalyst. Then, the catalyst was applied for the conversion of xylose and corn stalk into furfural in GVL. The influence of the reaction time, temperature and dosage of catalyst on xylose dehydration were also investigated. The Brønsted acid catalyst exhibited high activity in the dehydration of xylose, with a high furfural yield of 78.5% at 170°C in 30min. What's more, a 60.6% furfural yield from corn stalk was achieved in 100min at 200°C. The recyclability of the sulfonated carbon catalyst was perfect, and it could be reused for 5times without the loss of furfural yields.

  14. Pramoninės žuvininkystės tvenkinių ūkių veiklos įtaka vandens kokybei

    OpenAIRE

    Kračka, Deividas

    2014-01-01

    Baigiamajame darbe nagrinėjama keturių Lietuvos pramoninės žuvininkystės ūkių į aplinką išleidžiama tarša (tiekiamo ir išleidžiamo vandens) pagal skendinčias medžiagas, BDS7, bendrą azotą ir bendrą fosforą ir pateikiamos rekomendacijos tvenkininių ūkių vandens kokybei gerinti. Darbo objektas: paviršinis vanduo. Darbo metodai – vertinama paviršinio vandens kokybė žuvininkystės ūkiuose aukščiau ir žemiau tvenkinių (tiekiamo ir išleidžiamo vandens). Darbo rezultatai. Išanalizavus dau...

  15. Determination of related substances in lisinopril and amlodipine tablets by HPLC

    Institute of Scientific and Technical Information of China (English)

    Dao-Rui Yu; Gui-Fang Yang; Wen-Li Xiao; Jun Wang; Qi-Bing Liu

    2016-01-01

    Objective:To establish an HPLC method for determining the related substances in lisinopril and amlodipine tablets.Methods:An Inertsil Thermo BDS HYPERSIL C18 (4.6 mmí250 mm, 5 μm) column was used with the Acetonitrile-water-phosphoric acid (10:90:0.1) as mobile phase A and Acetonitrile-water-phosphoric acid (90:10:0.1) as mobile phase B by gradient elution at the detection wavelength of 215 nm. The flow rate was 1.0 mL/min and the column temperature was 30℃.Results: The separation of the impurity peak and peak was good. Besides, all the impurities could be detected effectively.Conclusions:The method is sensitive, accurate and selective. It is suitable for control the related substances in lisinopril and Amlodipine tablets.

  16. On a residual freedom of the next-to-leading BFKL eigenvalue in color adjoint representation in planar $\\mathcal{N} = 4$ SYM

    CERN Document Server

    Bondarenko, Sergey

    2016-01-01

    We discuss a residual freedom of the next-to-leading BFKL eigenvalue that originates from ambiguity in redistributing the next-to-leading~(NLO) corrections between the adjoint BFKL eigenvalue and eigenfunctions in planar $\\mathcal{N}=4$ super-Yang-Mills~(SYM) Theory. In terms of the remainder function of the Bern-Dixon-Smirnov~(BDS) amplitude this freedom is translated to reshuffling correction between the eigenvalue and the impact factors in the multi-Regge kinematics~(MRK) in the next-to-leading logarithm approximation~(NLA). We show that the modified NLO BFKL eigenvalue suggested by the authors can be introduced in the MRK expression for the remainder function by shifting the anomalous dimension in the impact factor in such a way that the two and three loop remainder function is left unchanged to the NLA accuracy.

  17. On a residual freedom of the next-to-leading BFKL eigenvalue in color adjoint representation in planar {N}=4 SYM

    Science.gov (United States)

    Bondarenko, Sergey; Prygarin, Alex

    2016-07-01

    We discuss a residual freedom of the next-to-leading BFKL eigenvalue that originates from ambiguity in redistributing the next-to-leading (NLO) corrections between the adjoint BFKL eigenvalue and eigenfunctions in planar {N}=4 super-Yang-Mills (SYM) Theory. In terms of the remainder function of the Bern-Dixon-Smirnov (BDS) amplitude this freedom is translated to reshuffling correction between the eigenvalue and the impact factors in the multi-Regge kinematics (MRK) in the next-to-leading logarithm approximation (NLA). We show that the modified NLO BFKL eigenvalue suggested by the authors in ref. [1] can be introduced in the MRK expression for the remainder function by shifting the anomalous dimension in the impact factor in such a way that the two and three loop remainder function is left unchanged to the NLA accuracy.

  18. 人参提取物中腐霉利残留的HPLC分析%Analysis of Procymidone Residues in Ginseng Extract by HPLC

    Institute of Scientific and Technical Information of China (English)

    任刚; 廖卫波; 胡志成; 易文芳; 刘荣华; 邵峰; 黄慧莲; 袁金斌

    2013-01-01

    目的:建立人参提取物中农药残留-腐霉利的HPLC含量测定方法.方法:BDS HYPERSIL C18分析色谱柱(4.6 mm × 250 mm,5 μm),流动相乙腈-水(40∶ 60),流速1.0 mL· min-1,检测波长220 nm.结果:腐霉利进样量0.001~0.6 μg与色谱峰面积呈良好线性关系(R2 =0.999 4),平均加样回收率100.0% (n=9),RSD 3.0%.结论:该法简便、准确、可靠,可用于人参提取物中腐霉利残留的含量测定.

  19. Detectability of substellar companions around white dwarfs with Gaia

    CERN Document Server

    Silvotti, Roberto; Lattanzi, Mario; Morbidelli, Roberto

    2014-01-01

    To date not a single-bona fide planet has been identified orbiting a single white dwarf. In fact we are ignorant about the final configuration of >95% of planetary systems. Theoretical models predict a gap in the final distribution of orbital periods, due to the opposite effects of stellar mass loss (planets pushed outwards) and tidal interactions (planets pushed inwards) during the RGB and the AGB stellar expansions. Over its five year primary mission, Gaia is expected to astrometrically detect the first (few tens of) WD massive planets/BDs giving first evidence that WD planets exist, at least those in wide orbits. In this article we present preliminary results of our simulations of what Gaia should be able to find in this field.

  20. Determination of free urinary cortisol in cushing's syndrome using reversed-phase high performance liquid chromatography

    Directory of Open Access Journals (Sweden)

    Eduardo Kinio Sugawara

    2010-01-01

    Full Text Available Determination of free urinary cortisol is a test of choice in the diagnosis of Cushing's syndrome. In this study, cortisol was quantified using reversed-phase high-performance liquid chromatography (RP-HPLC in urine samples previously extracted with ether and using triamcinolone acetonide as internal standard (IS. A BDS-Hypersil-C18® column, water-acetonitrile (72:28; v/v, with a flow rate of 1.0 mL/min and detection at 243 nm were used. This method showed to be both effective and efficient, with sensitivity and linearity ranging from 2.50 to 150 μg/L, and can be used in substitution to the radioimmunoassay technique within this concentration range.

  1. Thermal, structural and electrical studies of bismuth zinc borate glasses

    Science.gov (United States)

    Shanmugavelu, B.; Ravi Kanth Kumar, V. V.

    2013-06-01

    Bismuth Zinc Borate glasses with compositions xBi2O3-30ZnO-(70 - x)B2O3 (where x = 30, 35, 40 and 45 mol %) have been prepared by melt quenching method. These glasses were characterized by X-ray diffraction (XRD), Differential Thermal Analysis (DTA), Fourier Transform Infrared Spectrometer (FTIR) and Broad Band Dielectric Spectrometer (BDS). DTA and FTIR analysis reveals that Non-Bridging Oxygens (NBOs) increase with increase of bismuth content in the glass. Electrical data have been analyzed in the framework of impedance and modulus formalisms. The activation energy for dc conductivity decreases with increase of bismuth concentration. The imaginary part of modulus spectra has been fitted to non-exponential Kohlrausch-Williams-Watts (KWW) function and the value of the stretched exponent (β) is found to be almost independent of temperature but slightly dependent on composition.

  2. Determination of racecadotril by HPLC in capsules

    Directory of Open Access Journals (Sweden)

    Prabu S

    2007-01-01

    Full Text Available A simple, precise and rapid RP-HPLC method was developed for the determination of racecadotril in a pharmaceutical formulation using gemfibrozil as internal standard. Ratio of the peak area of analyte to internal standard was used for quantification. The chromatographic separation was carried out by using a Reverse Phase C18 column (BDS-Hypersil. The mobile phase consisting of a mixture of 20 mM phosphate buffer (pH 3.5 and acetonitrile in the ratio of (40:60 with detection at 230 nm at a flow rate of 1 ml/min was employed. The method was statistically validated for linearity, accuracy and precision. The elution time was 6.9 min for racecadotril and 9.8 min for gemfibrozil. The simplicity and accuracy of the proposed method ensures its use in routine quality control analysis of pharmaceutical formulations.

  3. MICROLENSING DISCOVERY OF A POPULATION OF VERY TIGHT, VERY LOW MASS BINARY BROWN DWARFS

    Energy Technology Data Exchange (ETDEWEB)

    Choi, J.-Y.; Han, C. [Department of Physics, Institute for Astrophysics, Chungbuk National University, Cheongju 371-763 (Korea, Republic of); Udalski, A. [Warsaw University Observatory, Al. Ujazdowskie 4, 00-478 Warszawa (Poland); Sumi, T. [Department of Earth and Space Science, Osaka University, Osaka 560-0043 (Japan); Gaudi, B. S.; Gould, A. [Department of Astronomy, Ohio State University, 140 West 18th Avenue, Columbus, OH 43210 (United States); Bennett, D. P. [Department of Physics, University of Notre Dame, 225 Nieuwland Science Hall, Notre Dame, IN 46556-5670 (United States); Dominik, M. [SUPA, School of Physics and Astronomy, University of St Andrews, North Haugh, St Andrews KY16 9SS (United Kingdom); Beaulieu, J.-P. [Institut dAstrophysique de Paris, UMR7095 CNRS-Universite Pierre and Marie Curie, 98 bis boulevard Arago, F-75014 Paris (France); Tsapras, Y. [Las Cumbres Observatory Global Telescope Network, 6740B Cortona Drive, Goleta, CA 93117 (United States); Bozza, V. [INFN, Sezione di Napoli, I-80126 Napoli (Italy); Abe, F.; Furusawa, K.; Itow, Y. [Solar-Terrestrial Environment Laboratory, Nagoya University, Nagoya 464-8601 (Japan); Bond, I. A.; Ling, C. H. [Institute of Information and Mathematical Sciences, Massey University, Private Bag 102-904, North Shore Mail Centre, Auckland 0745 (New Zealand); Botzler, C. S.; Freeman, M. [Department of Physics, University of Auckland, Private Bag 92-019, Auckland 1001 (New Zealand); Chote, P. [School of Chemical and Physical Sciences, Victoria University, Wellington 6140 (New Zealand); Fukui, A. [Okayama Astrophysical Observatory, National Astronomical Observatory of Japan, Asakuchi, Okayama 719-0232 (Japan); Collaboration: MOA Collaboration; OGLE Collaboration; muFUN Collaboration; MiNDSTEp Consortium; PLANET Collaboration; RoboNet Collaboration; and others

    2013-05-10

    Although many models have been proposed, the physical mechanisms responsible for the formation of low-mass brown dwarfs (BDs) are poorly understood. The multiplicity properties and minimum mass of the BD mass function provide critical empirical diagnostics of these mechanisms. We present the discovery via gravitational microlensing of two very low mass, very tight binary systems. These binaries have directly and precisely measured total system masses of 0.025 M{sub Sun} and 0.034 M{sub Sun }, and projected separations of 0.31 AU and 0.19 AU, making them the lowest-mass and tightest field BD binaries known. The discovery of a population of such binaries indicates that BD binaries can robustly form at least down to masses of {approx}0.02 M{sub Sun }. Future microlensing surveys will measure a mass-selected sample of BD binary systems, which can then be directly compared to similar samples of stellar binaries.

  4. RP-HPLC METHOD FOR SIMULTATANEOUS DETERMINATION OF IRBESARTAN, LOSARTAN, HYDRO-CHLOROTHIAZIDE AND CHLORTHALIDONE–APPLICATION TO COMMERCIALLY AVAILABLE DRUG PRODUCTS

    Directory of Open Access Journals (Sweden)

    R. A. Mhaske et al.

    2012-04-01

    Full Text Available A simple, precise and stability-indicating HPLC method was developed and validated for the simultaneous determination of anti-hypertensive drugs Irbesartan, Losartan, diuretics Hydrochlorothiazide and Chlorthalidone. The separation was achieved on Hypersil BDS (Length 250 mm × Diameter 4.6 mm Particle size 5 μm column with gradient flow. The mobile phase at a flow rate of 1.0 mL min−1 consisted of 0.05 M sodium dihydrogen phosphate buffer and acetonitrile (Gradient ratio. The UV detection was carried out at 220 nm. The method was successfully validated in accordance to ICH guidelines. Further, the validated method was applied for commercially available pharmaceutical dosage form.

  5. HPLC Method for the Determination of Tamsulosin Hydrochloride in Sustained Release Tablets

    Institute of Scientific and Technical Information of China (English)

    齐美玲; 王鹏; 耿颖姝; 顾峻岭

    2003-01-01

    The development and validation of an isocratic high performance liquid chromatographic method is described for the determination of tamsulosin hydrochloride in sustained release tablets. The determination was performed on a Diamonsil BDS C18 column with a mobile phase consisting of a mixture of acetonitrile, methanol and 0.5% phosphoric acid solution (20∶30∶50,V/V/V) at a flow rate of 1.0 mL/min. UV detection was made at 274 nm. The linear range for tamsulosin hydrochloride was 0.81-8.10 μg/mL. The mean recovery was 99.8% (SR=0.7%, n=9), and the precision was found to be 0.45% (n=9). The proposed method can be used for routine analysis of tamsulosin hydrochloride in sustained release tablets.

  6. Analytical Method Development and Validation of Related Substance Method for Bortezomib for Injection 3.5 mg/Vial by RP-HPLC Method

    Directory of Open Access Journals (Sweden)

    Utage M

    2013-04-01

    Full Text Available An accurate, precise, simple and economical High Performance Liquid Chromatographic method for therelated substance determination of Bortezomib in its lyophilized dosage form has been developed. Themethod developed is Reverse Phase High Performance Liquid Chromatographic method using HypersilBDS C18 column (Length: 150mm, Diameter: 4.6mm, Particle size: 5μ with Gradient programmed anda simple Acetonitrile, Water and Formic acid in the ratio of 30:70:0.1 (v/v/v respectively as mobilephase A and Acetonitrile, Water and Formic acid in the ratio of 80:20:0.1 (v/v/v respectively. Themethod so developed was validated in compliance with the regulatory guidelines by using welldeveloped analytical method validation tool which comprises with the analytical method validationparameters like Linearity, Accuracy, Method precision, Specificity with forced degradation, Systemsuitability, Robustness, LOD, LOQ and Ruggedness. The results obtained were well within theacceptance criteria.

  7. Experimental and casework validation of ambient temperature corrections in forensic entomology.

    Science.gov (United States)

    Johnson, Aidan P; Wallman, James F; Archer, Melanie S

    2012-01-01

    This paper expands on Archer (J Forensic Sci 49, 2004, 553), examining additional factors affecting ambient temperature correction of weather station data in forensic entomology. Sixteen hypothetical body discovery sites (BDSs) in Victoria and New South Wales (Australia), both in autumn and in summer, were compared to test whether the accuracy of correlation was affected by (i) length of correlation period; (ii) distance between BDS and weather station; and (iii) periodicity of ambient temperature measurements. The accuracy of correlations in data sets from real Victorian and NSW forensic entomology cases was also examined. Correlations increased weather data accuracy in all experiments, but significant differences in accuracy were found only between periodicity treatments. We found that a >5°C difference between average values of body in situ and correlation period weather station data was predictive of correlations that decreased the accuracy of ambient temperatures estimated using correlation. Practitioners should inspect their weather data sets for such differences.

  8. Molecular probe dynamics and free volume in organic glass-formers and their relationships to structural relaxation: 1-propanol

    International Nuclear Information System (INIS)

    A joint study of the rotational dynamics and free volume in amorphous 1-propanol (1-PrOH) as a prototypical monohydroxy alcohol by electron spin resonance (ESR) or positron annihilation lifetime spectroscopy (PALS), respectively, is reported. The dynamic parameters of the molecular spin probe 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO) and the annihilation ones of the atomic ortho-positronium (o-Ps) probe as a function of temperature are compared. A number of coincidences between various effects in the ESR and PALS responses at the corresponding characteristic ESR and PALS temperatures were found suggesting a common origin of the underlying dynamic processes that were identified using viscosity (VISC) in terms of the two-order parameter (TOP) model and broadband dielectric spectroscopy (BDS) data. (paper)

  9. Analytic properties of high energy production amplitudes in N=4 SUSY

    Energy Technology Data Exchange (ETDEWEB)

    Lipatov, L.N. [St. Petersburg Inst. of Nuclear Physics, Gatchina (Russian Federation); Hamburg Univ. (Germany). 1. Inst. fuer Theoretische Physik

    2010-08-15

    We investigate analytic properties of the six point planar amplitude in N=4 SUSY at the multi-Regge kinematics for final state particles. For inelastic processes the Steinmann relations play an important role because they give a possibility to fix the phase structure of the Regge pole and Mandelstam cut contributions. The analyticity and factorization constraints allow us to reproduce the two-loop correction to the 6- point BDS amplitude in N=4 SUSY obtained earlier in the leading logarithmic approximation with the use of the s-channel unitarity. The cut contribution has the Moebius invariant form in the transverse momentum subspace. The exponentiation hypothesis for the amplitude in the multi-Regge kinematics is also investigated in LLA. (orig.)

  10. The Genetic diversity of Bangladeshi Buffaloes

    Directory of Open Access Journals (Sweden)

    M.O. Faruque

    2010-02-01

    Full Text Available The most buffaloes in Bangladesh are indigenous in origin. There are 5 populations of buffaloes in Bangladesh. Karyotypic experiment indicated that Bangladesh East population had 48 chromosomes while other populations had 50 chromosomes. Blood protein polymorphism study revealed the existence of polymorphism for 7 loci: albumin, transferrin, hemoglobin-α, hemoglobin-β, carbonic anhydrase, alkaline phosphatase and peptidase-B. AlbX, gene for typical swamp buffalo, was detected in populations of BDE and BDS. Another gene of swamp buffalo viz., TfA was found only in the population of BDE. mtDNA study further confirmed the occurrence of haplotypes for swamp buffaloes in BDE. Swamp buffaloes are distributed in the northeastern part of Bangladesh. River buffaloes are distributed other parts of Bangladesh.

  11. Exercise dependence and the drive for muscularity in male bodybuilders, power lifters, and fitness lifters.

    Science.gov (United States)

    Hale, Bruce D; Roth, Andrew D; DeLong, Ryan E; Briggs, Michael S

    2010-06-01

    Researchers have hypothesized differences in exercise dependence and drive for muscularity between bodybuilders and power lifters, while others have not found the predicted differences. This study assessed 146 weight lifters (bodybuilders, n=59; power lifters, n=47; fitness lifters, n=40) on the Exercise Dependence Scale, Bodybuilding Dependence Scale, and the Drive for Muscularity Scale. Results showed that bodybuilders and power lifters were significantly higher than fitness lifters on EDS Total, 7 EDS scales, and the 3 BDS scales. In contrast, power lifters were found to be significantly higher on DMS Total and DMS Behavior scales than bodybuilders. The regression results suggest that exercise dependence may be directly related to the drive for muscularity.

  12. Desarrollo y evaluación de una aplicación Web estandarizada para el almacenamiento e intercambio de Historiales Clínicos Electrónicos (HCEs) en oftalmología: TeleOftalWeb

    OpenAIRE

    Torre Díez, Isabel de la

    2010-01-01

    El objetivo de la presente Tesis es el desarrollo, puesta en marcha y evaluación de la aplicación Web, TeleOftalWeb, en sus cuatro versiones, destinada al almacenamiento e intercambio de Historiales Clínicos Electrónicos (HCEs) y retinografías. Cada una de las versiones está desarrollada con diferentes modelos de bases de datos (BDs): dbXML 2.0 más MySQL 5.0, eXist 1.1.1 más MySQL, Xindice 1.2. más MySQL 5.0 y Oracle 10g. A su vez, se estudiarán los estándares de HCE más relevantes entre ello...

  13. Glassy dynamics and physical aging in fucose saccharides as studied by infrared- and broadband dielectric spectroscopy.

    Science.gov (United States)

    Kossack, Wilhelm; Adrjanowicz, Karolina; Tarnacka, Magdalena; Kipnusu, Wycliffe Kiprop; Dulski, Mateusz; Mapesa, Emmanuel Urandu; Kaminski, Kamil; Pawlus, Sebastian; Paluch, Marian; Kremer, Friedrich

    2013-12-21

    Fourier Transform Infra Red (FTIR) and Broadband Dielectric Spectroscopy (BDS) are combined to study both the intra- and inter-molecular dynamics of two isomers of glass forming fucose, far below and above the calorimetric glass transition temperature, T(g). It is shown that the various IR-active vibrations exhibit in their spectral position and oscillator strength quite different temperature dependencies, proving their specific signature in the course of densification and glass formation. The coupling between intra- and inter molecular dynamics is exemplified by distinct changes in IR active ring vibrations far above the calorimetric glass transition temperature at about 1.16T(g), where the dynamic glass transition (α relaxation) and the secondary β relaxation merge. For physically annealed samples it is demonstrated that upon aging the different moieties show characteristic features as well, proving the necessity of atomistic descriptions beyond coarse-grained models.

  14. BFKL Pomeron and Bern-Dixon-Smirnov amplitudes in N=4 SUSY

    International Nuclear Information System (INIS)

    We review the theoretical approaches for investigations of the high energy hadron-hadron scattering in the Regge kinematics. It is demonstrated, that the gluon in QCD is reggeized and the Pomeron is a composite state of the reggeized gluons. Remarkable properties of the BFKL equation for the Pomeron wave function in QCD and supersymmetric gauge theories are outlined. Due to the AdS/CFT correspondence the BFKL Pomeron is equivalent to the reggeized graviton in the extended N=4 SUSY. The properties of the maximal transcendentality and integrability are realized in this model. The BDS multi-gluon scattering amplitudes are investigated in the Regge limit. They do not contain the Mandelstam cuts and are not valid beyond one loop. It is shown, that the hamiltonian for these composite states coincides with the hamiltonian of an integrable open Heisenberg spin chain. (orig.)

  15. Simultaneous determination of cefixime trihydrate and dicloxacillin sodium in pharmaceutical dosage form by reversed-phase high-performance liquid chromatography.

    Science.gov (United States)

    Dhoka, Madhura V; Sandage, Shakuntala J; Dumbre, Snehal C

    2010-01-01

    A simple, precise, accurate, and sensitive RP-HPLC method for simultaneous determination of cefixime trihydrate and dicloxacillin sodium in combined tablet dosage form was developed and validated. Chromatographic separation of the two drugs was performed on a Purospher BDS C18 column (25 cm x 4.6 mm id, 5 microm particle size). The mobile phase methanol-0.01 M phosphate buffer (75 + 25, v/v), adjusted to pH 3 with glacial acetic acid, was delivered at a flow rate of 1.0 mL/min. Detection was performed at 227 nm. Separation was completed within 10 min. Calibration curves were linear with R2 between 0.99 to 1.0 over a concentration range of 2-10 microg/mL for cefixime trihydrate and 5-25 micromL for dicloxacillin sodium. The RSD for intraday and interday precision was < 2.0%. PMID:20480900

  16. Temperature dependence of the dielectric constant of acrylic dielectric elastomer

    Energy Technology Data Exchange (ETDEWEB)

    Sheng, Junjie; Chen, Hualing; Li, Bo; Chang, Longfei [Xi' an Jiaotong University, State Key Laboratory for Strength and Vibration of Mechanical Structures, Xi' an (China); Xi' an Jiaotong University, School of Mechanical Engineering, Xi' an (China)

    2013-02-15

    The dielectric constant is an essential electrical parameter to the achievable voltage-induced deformation of the dielectric elastomer. This paper primarily focuses on the temperature dependence of the dielectric constant (within the range of 173 K to 373 K) for the most widely used acrylic dielectric elastomer (VHB 4910). First the dielectric constant was investigated experimentally with the broadband dielectric spectrometer (BDS). Results showed that the dielectric constant first increased with temperature up to a peak value and then dropped to a relative small value. Then by analyzing the fitted curves, the Cole-Cole dispersion equation was found better to characterize the rising process before the peak values than the Debye dispersion equation, while the decrease process afterward can be well described by the simple Debye model. Finally, a mathematical model of dielectric constant of VHB 4910 was obtained from the fitted results which can be used to further probe the electromechanical stability of the dielectric elastomers. (orig.)

  17. Measurement of the Absolute Branching Fraction of D_s^+ --> tau^+ nu_tau Decay

    CERN Document Server

    Ecklund, K M; Savinov, V; López, A; Méndez, H; Ramírez, J; Ge, J Y; Miller, D H; Shipsey, I P J; Xin, B; Adams, G S; Anderson, M; Cummings, J P; Danko, I; Hu, D; Moziak, B; Napolitano, J; He, Q; Insler, J; Muramatsu, H; Park, C S; Thorndike, E H; Yang, F; Artuso, M; Blusk, S; Khalil, S; Li, J; Mountain, R; Nisar, S; Randrianarivony, K; Sultana, N; Skwarnicki, T; Stone, S; Wang, J C; Zhang, L M; Bonvicini, G; Cinabro, D; Dubrovin, M; Lincoln, A; Rademacker, J; Asner, D M; Edwards, K W; Naik, P; Reed, J; Briere, R A; Ferguson, T; Tatishvili, G; Vogel, H; Watkins, M E; Rosner, J L; Alexander, J P; Cassel, D G; Duboscq, J E; Ehrlich, R; Fields, L; Gibbons, L; Gray, R; Gray, S W; Hartill, D L; Heltsley, B K; Hertz, D; Jones, C D; Kandaswamy, J; Kreinick, D L; Kuznetsov, V E; Mahlke-Krüger, H; Mohapatra, D; Onyisi, P U E; Patterson, J R; Peterson, D; Riley, D; Ryd, A; Sadoff, A J; Shi, X; Stroiney, S; Sun, W M; Wilksen, T; Athar, S B; Patel, R; Yelton, J; Rubin, P; Eisenstein, B I; Karliner, I; Mehrabyan, S; Lowrey, N; Selen, M; White, E J; Wiss, J; Mitchell, R E; Shepherd, M R; Besson, D; Pedlar, T K; Cronin-Hennessy, D; Gao, K Y; Hietala, J; Kubota, Y; Klein, T; Lang, B W; Poling, R; Scott, A W; Zweber, P; Dobbs, S; Metreveli, Z; Seth, K K; Tomaradze, A G; Libby, J; Powell, A; Wilkinson, G

    2007-01-01

    Using a sample of tagged D_s decays collected near the D^*_s D_s peak production energy with the CLEO-c detector, we study the leptonic decay D^+_s to tau^+ nu_tau via the decay channel tau^+ to e^+ nu_e bar{nu}_tau. We measure B(D^+_s to tau^+ nu_tau) = (6.17 +- 0.71 +- 0.34) %. Combining with our measurements of D^+_s to mu^+ nu_mu and D^+_s to tau^+ nu_tau (via tau^+ to pi^+ bar{nu}_tau), we determine f_{D_s} = 274 +- 10 +- 5 MeV.

  18. Cold Brown Dwarfs with WISE: Y Dwarfs and the Field Mass Function

    Science.gov (United States)

    Kirkpatrick, J. Davy

    2012-01-01

    Why study Brown Dwarf stars? They re the lowest mass byproducts of star formation.. They provide time capsules across the age of the Galaxy.. They show what low-T(sub eff) atmospheres look like.. They may be some of our closest neighbors in space..WISE is a 40cm Earth-orbiting telescope. There are 211 stars and only 33 brown dwarfs in this volume.. This means that stars outnumber brown dwarfs by a factor of 6:1 currently.. The number of brown dwarfs will continue to increase if:: (a) more nearby Y dwarf candidates are confirmed, or (b) our distances to known Y s are overestimated, or (c) there are colder BDs invisible to WISE..

  19. THE ROLE OF STUDENT CHARACTERISTICS IN PROBLEM BASED LEARNING

    Directory of Open Access Journals (Sweden)

    Mia Damiyanti

    2006-04-01

    Full Text Available To reach the effectiveness of study, it is recommended to work on active learning method. The learning activity must be done with emphasis on the students’ characteristics. The characteristic means internal factors (cognitive entry behavior and affective entry characteristics, which are considered important as solving problems. The previous studies have shown that there is a correlation between achievement test and students’ characteristic entry behavior. At the beginning of the academic year of 2003, Faculty of Dentistry, University of Indonesia started active learning with PBL curriculum for the BDS degree. From a study about the correlation between the achievement and students’ entry behavior (previous knowledge, self concept, attitude, and anxiety during attending the test the study showed that characteristic entry behavior contributes to the student’s achievement test. The results supported the previous study.

  20. GNSS多系统基线解算中的病态性分析与评价%Analysis and valuation of ill-condition in baseline solution of GNSS multi-system

    Institute of Scientific and Technical Information of China (English)

    王胜利; 王庆; 高旺; 潘树国

    2013-01-01

    Aiming at the different situations of satellites orbital altitude and angular velocity in GNSS (global navigation satellite system) multi-system,the ill-condition in baseline solution was analyzed and evaluated combined with the analysis theory on ill-conditioned system.First,the effect of illcondition on the solution of parameters was analyzed.Then,form the viewpoint of satellites' angular velocities,the ill-condition in independent baseline solution of the GPS (global positioning system),GLONASS (global navigation satellite system) and BDS (Beidou navigation satellite system) under different baseline-length data was studied by using the condition-number method.Finally,the illcondition in multi-system integration was valuated.The experimental results show that the GLONASS satellites run fastest,so the ill-condition is the weakest and the coefficient matrix structure is the best.However,the ill-condition of the current BDS which mainly consists of high-orbit satellites is the strongest.Besides,the ill-condition in baseline solution is not related with the baseline length.For multi-system integration,the coefficient matrix structure is not obviously affected by the serious ill-condition of the BDS,which is conducive to the fast convergence of ambiguities resolution in baseline solution of the BDS.%针对各GNSS系统中不同的卫星轨道高度和运行角速度,结合病态性系统分析理论,对GNSS多系统基线解算中的病态性进行了分析和评价.首先,分析了病态性对参数求解的影响;然后,从卫星运动的角速度出发,采用条件数法对GPS,GLONASS以及北斗区域导航系统在独立解算不同长度基线中的病态性进行了对比研究;最后,对多系统融合之后模糊度解算过程中的病态性进行了评价.实验结果表明,GLONASS卫星运动的角速度最快,基线解算过程的病态性最弱,系数矩阵结构最好;以高轨卫星为主的北斗系统的病态性则最强.此外,基线解算过程

  1. Continuing professional development of dentists through distant learning: An Indira Gandhi National Open University-Dental Council of India experiment a report

    Directory of Open Access Journals (Sweden)

    Ruchika Kuba

    2014-01-01

    Full Text Available To keep themselves updated with all the advancements in the field of dentistry, dentists should involve themselves in some kind of professional development. Distance learning is the most appropriate way to serve the growing demand due to technological advancements. Indira Gandhi National Open University in collaboration with Dental Council of India (DCI developed and launched two continuing professional development programs in Endodontics (postgraduate certificate in endodontics and postgraduate certificate in oral implantology and has trained over 400 and 280 BDS dentists respectively till date. The program package consists of self-instructional material, assignments, videos and practical training. The training is conducted in premiere dental colleges and institutions recognized by DCI. The certificate is awarded after a term end examination, both in theory and practical. The pass percentages of the theory courses ranged from around 63% to 98%, and 90% of the candidates cleared the practical exam.

  2. Crystallization behavior and dielectric properties of K{sub 2}O–SrO–Nb{sub 2}O{sub 5}–B{sub 2}O{sub 3}–Al{sub 2}O{sub 3}–SiO{sub 2} glass-ceramic for energy storage

    Energy Technology Data Exchange (ETDEWEB)

    Xiao, Shi; Xiu, Shaomei; Xue, Shuangxi; Shen, Bo; Zhai, Jiwei, E-mail: apzhai@tongji.edu.cn

    2015-11-05

    A new K{sub 2}O–SrO–Nb{sub 2}O{sub 5}–B{sub 2}O{sub 3}–Al{sub 2}O{sub 3}–SiO{sub 2} (KSN-BAS) glass-ceramic system has been prepared by conventional controlled-crystallization method. The crystallization behavior and dielectric properties of the glass-ceramics were investigated. The X-ray diffraction analysis showed that the KSr{sub 2}Nb{sub 5}O{sub 15} and SrNb{sub 2}O{sub 6} phases with tungsten bronze structure were precipitated from the glass matrix, as the crystallization temperature increased, the AlNbO{sub 4} phase was observed. The microstructure observed the sizes of grains became larger and presented the grain reunion severely. The dielectric constants of all the samples exhibited excellent stability from −90 °C to 120 °C and low dielectric losses less than 0.03. A maximum dielectric constant was obtained at annealing of 900 °C. The dielectric breakdown strength (BDS) reduced as the crystallization temperature increased. A maximum BDS can attain1213.76 kV/cm and a maximum energy storage density can reach up to 4.41 J/cm{sup 3}. - Highlights: • The energy storage density of original glass-ceramic can reach to 4.41 J/cm{sup 3}. • The single phase of high dielectric constant can be found in this glass-ceramic. • The material is regarded as a linear material without any ferroelectric behavior. • The heat treatment method is used to study the new glass-ceramic system. • The paper elaborated the effect of crystallization temperature on the properties.

  3. Determination of grass enema Verbena gallic acid in by HPLC%HPLC法测定地锦草灌肠液中没食子酸的含量

    Institute of Scientific and Technical Information of China (English)

    佘永红; 周顺

    2011-01-01

    目的:建立地锦草灌肠液中没食子酸的含量测定.方法:采用HPLC法,色谱柱为BDS Hypersil C18(250 mm×4.6mm,5μm);流动相为甲醇-0.05%磷酸溶液(10∶90);流速为0.8 mL·min-1;检测波长为266 nm;柱温为室温,进样量为10 μL.结果:没食子酸在0.07116-0.49812 μg范围内呈良好的线形关系(r=0.9998),平均回收率为100.7%,RSD%为1.1%(n=6).结论:该方法简便,准确,重现性好,可用于地锦草灌肠液的质量控制.%Objective: To establish a creeper grass enema Determination of gallic acid. Methods: HPLC,column was BDS Hypersil C18(25 mmx4.6 mm,5 μm), mobile phase of methanol-0.05% phosphoric acid water(10∶90), flow rate of 0.8 mL-min-1,the detection wavelength was 266 nm, column temperature was room temperature, the injection volume was 10 μL.Results:Gallic acid in the range of 0.07116-0.49812 μg showed a good linear relationship (r=0.9998),the average recovery was100.7%,RSD% was 1.1% (n=6).Conclusion: The method is simple, accurate, reproducible, and can be used for Euphorbia humifusa enema quality control.

  4. Engineered safety in development of liquid poison injection system (shut down system-2) for 500 MWe PHWR

    International Nuclear Information System (INIS)

    Full text: The provision of shut down systems (SDS) is a mandatory requirement for safety of any nuclear reactor. The SDS shall be capable of making and holding the core adequately subcritical in the event of any anticipated operational occurrence and postulated accident conditions. The shut down function will perform as intended when its design and components are thoroughly evaluated for their reliability and effectiveness. A full scale mock up for one injection unit was designed and developed at Hall No.7, BARC. Experimental studies were carried out to qualify the design and evolve process parameters such as gas tank pressure, poison discharge rate and poison injection time. In liquid poison injection system i.e. shutdown system -2, there is no physical barrier, between the two liquids i.e. the poison and the moderator. A liquid in liquid interface, called poison moderator interface (PMI) separates these fluids. Extensive lab scale studies have been carried out on PMI movement study i.e. the interface movement due to molecular diffusion and due to process disturbances under simulated reactor condition. On the basis of lab scale results, a full-scale PMI setup has been designed and developed to generate plant data. From reactor safety consideration, the floating ball in poison tank is designed in such a way that it prevents the over pressurisation of calandria. For this purpose a non-intrusive ultrasonic ball detection system (U-BDS) has been developed. This paper covers the PMI system for 500 MWe PHWR with relevant safety aspects and describes in detail, the experimental results of PMI study. The engineered safety in design, methodology and qualification of U-BDS and its role intended in performance of SDS-2 have been also discussed in the paper

  5. Flash ionization signature in coherent cyclotron emission from brown dwarfs

    Science.gov (United States)

    Vorgul, I.; Helling, Ch.

    2016-05-01

    Brown dwarfs (BDs) form mineral clouds in their atmospheres, where charged particles can produce large-scale discharges in the form of lightning resulting in substantial sudden increase of local ionization. BDs are observed to emit cyclotron radio emission. We show that signatures of strong transient atmospheric ionization events (flash ionization) can be imprinted on a pre-existing radiation. Detection of such flash ionization events will open investigations into the ionization state and atmospheric dynamics. Such events can also result from explosion shock waves, material outbursts or (volcanic) eruptions. We present an analytical model that describes the modulation of a pre-existing electromagnetic radiation by a time-dependent (flash) conductivity that is characteristic for flash ionization events like lightning. Our conductivity model reproduces the conductivity function derived from observations of terrestrial gamma-ray flashes, and is applicable to astrophysical objects with strong temporal variations in the local ionization, as in planetary atmospheres and protoplanetary discs. We show that the field responds with a characteristic flash-shaped pulse to a conductivity flash of intermediate intensity. More powerful ionization events result in smaller variations of the initial radiation, or in its damping. We show that the characteristic damping of the response field for high-power initial radiation carries information about the ionization flash magnitude and duration. The duration of the pulse amplification or the damping is consistently shorter for larger conductivity variations and can be used to evaluate the intensity of the flash ionization. Our work suggests that cyclotron emission could be probe signals for electrification processes inside BD atmosphere.

  6. Challenges of diagnosing and managing the adolescent with heavy menstrual bleeding.

    Science.gov (United States)

    Zia, Ayesha; Rajpurkar, Madhvi

    2016-07-01

    Unpredictable, prolonged or heavy menstrual bleeding (HMB) may be expected for many adolescents soon after menarche. A decade of clinical experience and research has now established firmly that bleeding disorders (BD) are common in adolescents with HMB. Despite these advances, many questions remain, and several aspects of the diagnosis and management of BDs in adolescents are not supported by rigorous clinical trials. In this overview, four major areas will be discussed. First, we will discuss the frequency of BDs in young women with HMB. Up to 20% of older females with HMB are thought to have an underlying BD. Estimates from retrospective studies in adolescents suggest a prevalence that varies anywhere from 10 to 62%. Prospective studies with uniform hemostatic evaluation are needed to answer this question definitively. Second, we will review existing tools that help screen and diagnose adolescents with HMB with an underlying BD. Although identification of an underlying BD in older women with HMB is relatively straight forward, uncertainties remain for adolescents. Heavy menstrual bleeding in this age group may have different pathophysiological underpinnings than those in older women and may often be disregarded as anovulatory. There is an urgent need to develop novel tools, and evaluate existing diagnostic strategies in adolescents. Third, we will discuss the optimal medical management of HMB in young adolescents. As direct evidence is largely lacking, these areas are also subject to extrapolation from older women. Lastly, an important area- prediction, and management of future bleeding in those adolescents who are diagnosed with a mild BD-will be discussed. Throughout, areas of controversy and opportunities for further research are highlighted. PMID:27208978

  7. LC-MS/MS in the elucidation of an isomer of the recreational drug methylenedioxy ethylamphetamine: methylenedioxy dimethylamphetamine.

    Science.gov (United States)

    Casteele, Sofie R Vande; Bouche, Marie-Paule L; Van Bocxlaer, Jan F

    2005-09-01

    This paper describes the surplus value of a quadrupole-orthogonal acceleration TOF mass spectrometer, coupled to a liquid chromatographic separation system, for the unequivocal identification and structural elucidation of an unknown compound in the field of designer drugs. In a patient sample set (blood, tissues, vitreous humor, etc.), analyzed with a dedicated liquid chromatographic-fluorescence detection method for the determination of methylenedioxy amphetamine, methylenedioxy methamphetamine, and methylenedioxy ethylamphetamine (MDEA), a "strange" inexplicable peak appeared at a retention time not corresponding to any of our reference materials. Based on the identical excitation and emission wavelengths in detection, and a retention behavior comparable to MDEA, it was assumed that this unknown compound was an isomer of the recreational drug MDEA. With a simple and straightforward methodological crossover between LC fluorescence detection and LC-MS/MS, additional information for structural elucidation was easily obtained. Chromatographic separation was achieved on a Hypersil BDS C18 column (fluorescence detection part) and on a Hypersil BDS phenyl column (mass spectrometric detection part). MS showed that the unknown compound's molecular mass was identical to that of MDEA, and, in addition, its fragmentation pattern too proved quite similar to that of MDEA. A thorough literature overview and study of the fragmentation pattern by means of the MS/MS spectrum led to an evidence-based hypothesis of 3,4-methylenedioxy N,N-dimethylamphetamine (MDDM) being the unknown compound. To confirm this hypothesis, MDDM was synthesized and its presence in our biological sample was finally demonstrated by co-injection with alternatively synthesized MDDM and MDEA. This application shows the synergism between LC and MS in the elucidation of unknown compounds, nevertheless emphasizing the essence of chromatographic separation when dealing with isomers. PMID:16224967

  8. Data-driven Ontology Development: A Case Study at NASA's Atmospheric Science Data Center

    Science.gov (United States)

    Hertz, J.; Huffer, E.; Kusterer, J.

    2012-12-01

    Well-founded ontologies are key to enabling transformative semantic technologies and accelerating scientific research. One example is semantically enabled search and discovery, making scientific data accessible and more understandable by accurately modeling a complex domain. The ontology creation process remains a challenge for many anxious to pursue semantic technologies. The key may be that the creation process -- whether formal, community-based, automated or semi-automated -- should encompass not only a foundational core and supplemental resources but also a focus on the purpose or mission the ontology is created to support. Are there tools or processes to de-mystify, assess or enhance the resulting ontology? We suggest that comparison and analysis of a domain-focused ontology can be made using text engineering tools for information extraction, tokenizers, named entity transducers and others. The results are analyzed to ensure the ontology reflects the core purpose of the domain's mission and that the ontology integrates and describes the supporting data in the language of the domain - how the science is analyzed and discussed among all users of the data. Commonalities and relationships among domain resources describing the Clouds and Earth's Radiant Energy (CERES) Bi-Directional Scan (BDS) datasets from NASA's Atmospheric Science Data Center are compared. The domain resources include: a formal ontology created for CERES; scientific works such as papers, conference proceedings and notes; information extracted from the datasets (i.e., header metadata); and BDS scientific documentation (Algorithm Theoretical Basis Documents, collection guides, data quality summaries and others). These resources are analyzed using the open source software General Architecture for Text Engineering, a mature framework for computational tasks involving human language.

  9. Basic characterization of avian β-defensin genes in the Japanese quail, Coturnix japonica.

    Science.gov (United States)

    Ishige, Taichiro; Hara, Hiromi; Hirano, Takashi; Mannen, Hideyuki; Kono, Tomohiro; Hanzawa, Kei

    2016-03-01

    In this study, we identified a cluster of 14 avian β-defensins (AvBD; approximately 66 kbp) in the Japanese quail, Coturnix japonica. Except for AvBD12 (CjAvBD12) and -13, the CjAvBDs coding sequences exhibited greater than 78.0% similarity to the respective orthologous chicken AvBD genes (GgAvBD). The putative amino acid sequence encoded by each CjAvBD contained six cysteine residues and the GXC (X1-2) motif considered essential for the β-defensin family. Each CjAvBDs also formed a sub-group with the respective orthologous genes of various bird species in a phylogenetic tree analysis. Synteny between the CjAvBD cluster and GgAvBD cluster was confirmed. The CjAvBD cluster was mapped on the long-arm end of chromosome 3 by linkage analysis based on single nucleotide polymorphisms (SNPs) of CjAvBD1 and CjAvBD12 (approximately 46 kbp), as well as GgAvBD cluster. We also confirmed that CjAvBD1, -4, -5, -9, and -10 are transcribed in 20 tissues, including immune and digestive tissues. However, our experimental data indicated that the CjAvBD cluster lacks the AvBD3 and -7 loci, whereas the CjAvBD101α, -101β, and -101θ loci arose from gene duplication of the AvBD6 orthologous locus in the CjAvBD cluster after differentiation between Coturnix - Gallus. PMID:26338292

  10. 多频段圆极化微带天线的设计%Design of multi-band circular polarized microstrip antenna

    Institute of Scientific and Technical Information of China (English)

    王丽黎; 刘丽珍

    2014-01-01

    A multi-band circular polarized microstrip antenna for navigation satellite system is designed. To enhance the impedance bandwidth and realize right-handed circular polarization radiation,the CRLH transmission line phase shifter is used as a feed network,which also improves performance of circular polarization at the same time. The antenna has been designed to operate at the satellite navigation frequency bands including GPS, BDS-2 and GLONASS. Ansoft HFSS 13.0 software is used, and the results of the simulation show that the antenna can meet the requirements of the signals of navigation satellite system. The antenna has the characteristics of the compact, frequency bandwidth, small size, easy processing.%设计了一款应用于导航卫星系统的多频段圆极化微带天线。天线采用复合左右手传输线移相器作为馈电网络,展宽阻抗带宽并且实现了良好的右旋圆极化辐射。该天线工作在导航卫星系统GPS、BDS-2和 GLONASS 工作波段。采用 Ansoft HFSS 13.0软件仿真,仿真结果表明该天线能够满足导航卫星信号的要求。该天线具有结构紧凑、频带宽、体积小、易于加工等特点。

  11. Research and Design of Blood Detecting System Based on ARM and Operating System uC/OS-II%基于ARM和iC/OS—II血液医疗检测仪的设计与研究

    Institute of Scientific and Technical Information of China (English)

    薛俊

    2012-01-01

    本血液检测系统成功实现了系统数据的采集、批量数据存储、医学算法嵌入、人机交互、上下位机通信等各个模块,融入操作系统uC/OS-Ⅱ对模块和设备进行任务管理,协调各设备之间数据的通信和资源的有序访问。血检系统主板软件结构由简单到复杂、由层次到模块的形式来搭建骨架,依托uC/OS-Ⅱ操作系统邮箱队列机制,创造高低速数据访问模型的可容性,构建数据和软件源码的可穿插访问,最大效率地完成了系统需求。%The BDS completes all of the modules about the system data collection, bulk data storage, embedded physic computation, man-machine conversation,communication between the mother board and auxiliary machine, it uses the uC/OS-II to manage the tasks of modules or devices, completes the data communication among the different devices and makes the system resources being visited regularly. The motherboard of BDS is constructed by the software modality which is from simpleness to complexity or from structurelayers to modules, uses the Mail-box and Queue mechanism of uC/OS- II to create the compatibihty that modules can be visited by the high or low speed data. It constructs the visit that data or software can insert each other, and then completes the requirements of system efficiently.

  12. 基于时延的动态优先级调度算法%Delay-Based Dynamic Priority Queue Scheduling

    Institute of Scientific and Technical Information of China (English)

    张登银; 许扬扬; 蒋娟

    2011-01-01

    队列管理是提高网络 QoS 的一种有效方法.在基于时延的调度算法(BDS)基础上将时间片与优先级相结合,提出了一种基于时延的动态优先级调度算法(DDPQS).为了实现该算法,针对进入缓冲区的每个子队列设置一个计数器,以调整的计数器值为基准来动态的改变队列的优先级,从而达到队列调度的效果;又从研究该算法的过程中,发现其局限性,即计数器值对时间片过于敏感的问题,于是进一步采用设置阈值进行区分的方法来优化.优化前后的仿真结果表明,时延和吞吐率性能具有明显改善.%Queue management is an effective method to improve the QoS of network. Investigating queue management based on the delay scheduling (BDS), combining the time chip and priority, advances Delay-based Dynamic Priority Queue Scheduling (DDPQS) algorithm. To achieve the algorithm, sets a counter for every sub-queue entering the buffer. It dynamically adjusts the sub-queue priorities by the value of counters to achieve the effect of queue scheduling. During the research, the limitation was found that the counters are sensitive to the time chip. The paper uses threshold values to optimize the algorithm. The simulation results before and after the optimizations demonstrate that the performance of the delay and the throughput rate has significantly improved.

  13. Altered cutaneous expression of beta-defensins in dogs with atopic dermatitis.

    Science.gov (United States)

    van Damme, Catharina M M; Willemse, Ton; van Dijk, Albert; Haagsman, Henk P; Veldhuizen, Edwin J A

    2009-08-01

    Canine atopic dermatitis (AD) is a chronic allergic skin disorder with an immunopathogenesis comparable to that in humans with AD. The high frequency of recurrent infections with Staphylococcus pseudo intermedius and Malassezia pachydermatis may indicate a defective innate immune response in the skin of atopic dogs. Production of beta-defensins constitutes an important role in skin defense but information on canine beta-defensin localization and regulation is scarce. We conducted a gene-expression study of 16 canine beta-defensins (cBDs) in 11 tissues of healthy dogs, which revealed a variable expression of cBDs in different organ systems of the dog. In skin, three beta-defensins, cBD1, cBD103 and cBD107, were extensively expressed, while inconsistent expression of five other beta-defensins was detected. Using immunohistochemistry abundant expression of cBD103 peptide was detected in the epidermis, hair follicles and sebaceous glands, comparable to hBD3 expression in human skin. To examine the gene-expression of beta-defensins in atopic dogs, full thickness skin biopsy specimens (non-lesional and lesional) of 10 atopic dogs and 7 healthy dogs were examined with real-time PCR. A significant 12-fold increased expression of cBD1 was detected in lesional atopic skin compared to healthy skin, while non-lesional skin showed a 5-fold increase. Contrary to cBD1, expression of cBD103 was slightly (2-fold) downregulated in skin of atopic dogs. Gene-expression levels of S100A8, a marker for atopic dermatitis, were also highly upregulated in skin of atopic dogs, confirming the diagnostics of the skin biopsies. Taken together these results provide new evidence for a possible defect in the innate immune response of dogs with atopic dermatitis, and indicate the potential of the dog as a model for human AD. PMID:19576634

  14. Deformation effects on sub-barrier fusion cross sections in 16O+174,176Yb

    Science.gov (United States)

    Rajbongshi, Tapan; Kalita, K.; Nath, S.; Gehlot, J.; Banerjee, Tathagata; Mukul, Ish; Dubey, R.; Madhavan, N.; Lin, C. J.; Shamlath, A.; Laveen, P. V.; Shareef, M.; Kumar, Neeraj; Jisha, P.; Sharma, P.

    2016-05-01

    Background: Couplings with various reaction channels are known to enhance sub-barrier fusion cross sections by several orders in magnitude. However, a few open questions still remain. For example, the influence of higher order static deformations on sub-barrier fusion cross sections is yet to be comprehensively understood. Purpose: We study the role of hexadecapole nuclear deformation effect on sub-barrier fusion cross sections. Also, this work aims to extract hexadecapole deformation (β4) in nuclei in the lanthanide region. Method: The evaporation residue (ER) excitation functions for 16O+174,176Yb were measured at laboratory beam energies (Elab) in the range of 64.6-103.6 MeV. Measurements were carried out by employing the recoil mass spectrometer Heavy Ion Reaction Analyzer (HIRA) at IUAC, New Delhi. Fusion barrier distributions (BDs) were extracted from data. Results from the experiment were subjected to coupled-channels analysis, in which β4 was varied as a free parameter. Results: Experimental fusion cross sections at energies below the barrier expectedly showed strong enhancement compared to the predictions from the one-dimensional barrier penetration model. Data were satisfactorily reproduced after inclusion of negative β4 for both the targets in the coupled-channels calculation. Conclusions: The significant role of hexadecapole deformation was observed in the sub-barrier fusion of 16O+174,176Yb. The proposed value of β4 reproduced the measured fusion excitation function reasonably well. The BDs from these data were also extracted but no definitive conclusions could be drawn from them.

  15. Overall Design of Multi-band RF Retransmission Satellite Navigation Signals Simulator%多体制转发式卫星导航信号源的总体设计

    Institute of Scientific and Technical Information of China (English)

    许志民

    2014-01-01

    为解决机载接收机无法正常接收真实卫星导航信号的问题,提出了一种多体制转发式卫星导航信号源的总体设计方案,并分析了涉及的关键技术。采用“接收机+发射机”的原理,通过对卫星导航信号接收、解扩解调、抗干扰、频率变换、调制扩频和放大等处理,实现信号的转发。该方案支持当前全球多种主流卫星导航系统体制,例如 GPS、BDS 和 GLONASS 等信号,实际试验证明了其有效性。该技术方案还可用于导航设备研制、调试和通信导航的集成验证等特殊场景。%To solve the problem that airborne receiver cannot receive real satellite navigation signals,an o-verall design scheme of multi-band RF retransmission satellite navigation signals simulator is presented and related key techniques are analyzed. According to the principle of “a receiver+a transmitter”,the RF sig-nals of satellite are retransmitted through receiving navigation signal,de-spread-spectrum and demodula-tion,anti-interference processing,changing carrier frequency modulation and spread-spectrum amplifying. The scheme is suitable for GPS,BDS and GLONASS signals. Engineering application proves its effective-ness. The scheme can be used extensively in satellite navigation equipment development and verification of integration of communication and navigation.

  16. Expression and antimicrobial function of beta-defensin 1 in the lower urinary tract.

    Directory of Open Access Journals (Sweden)

    Brian Becknell

    Full Text Available Beta defensins (BDs are cationic peptides with antimicrobial activity that defend epithelial surfaces including the skin, gastrointestinal, and respiratory tracts. However, BD expression and function in the urinary tract are incompletely characterized. The purpose of this study was to describe Beta Defensin-1 (BD-1 expression in the lower urinary tract, regulation by cystitis, and antimicrobial activity toward uropathogenic Escherichia coli (UPEC in vivo. Human DEFB1 and orthologous mouse Defb1 mRNA are detectable in bladder and ureter homogenates, and human BD-1 protein localizes to the urothelium. To determine the relevance of BD-1 to lower urinary tract defense in vivo, we evaluated clearance of UPEC by Defb1 knockout (Defb1(-/- mice. At 6, 18, and 48 hours following transurethral UPEC inoculation, no significant differences were observed in bacterial burden in bladders or kidneys of Defb1(-/- and wild type C57BL/6 mice. In wild type mice, bladder Defb1 mRNA levels decreased as early as two hours post-infection and reached a nadir by six hours. RT-PCR profiling of BDs identified expression of Defb3 and Defb14 mRNA in murine bladder and ureter, which encode for mBD-3 and mBD-14 protein, respectively. MBD-14 protein expression was observed in bladder urothelium following UPEC infection, and both mBD-3 and mBD-14 displayed dose-dependent bactericidal activity toward UPEC in vitro. Thus, whereas mBD-1 deficiency does not alter bladder UPEC burden in vivo, we have identified mBD-3 and mBD-14 as potential mediators of mucosal immunity in the lower urinary tract.

  17. Comparing group-based acceptance and commitment therapy (ACT) with enhanced usual care for adolescents with functional somatic syndromes: a study protocol for a randomised trial

    Science.gov (United States)

    Kallesøe, Karen Hansen; Schröder, Andreas; Wicksell, Rikard K; Fink, Per; Ørnbøl, Eva; Rask, Charlotte Ulrikka

    2016-01-01

    Introduction Functional somatic syndromes (FSS) are common in adolescents, characterised by severe disability and reduced quality of life. Behavioural treatments such as acceptance and commitment therapy (ACT) has shown promising results in children and adolescents with FSS, but has focused on specific syndromes such as functional pain. The current study will compare the efficacy of group-based ACT with that of enhanced usual care (EUC) in adolescents with a range of FSS operationalised by the unifying construct of multiorgan bodily distress syndrome (BDS). Methods and analysis A total of 120 adolescents aged 15–19 and diagnosed with multiorgan BDS, of at least 12 months duration, will be assessed and randomised to either: (1) EUC: a manualised consultation with a child and adolescent psychiatrist and individualised treatment plan or (2) manualised ACT-based group therapy plus EUC. The ACT programme consists of 9 modules (ie, 27 hours) and 1 follow-up meeting (3 hours). The primary outcome is physical health, assessed by an Short Form Health Survey (SF-36) aggregate score 12 months after randomisation. Secondary outcomes include self-reported symptom severity, symptom interference, depression and anxiety, illness worry, perceived stress and global improvement; as well as objective physical activity and bodily stress response measured by heart rate variability, hair cortisol and inflammatory biomarkers. Process measures are illness perception, illness-related behaviour and psychological flexibility. Ethics and dissemination The study is conducted in accordance with Helsinki Declaration II. Approval has been obtained from the Science Ethics Committee of the Central Denmark Region and the Danish Data Protection. The results will be sought to be published according to the CONSORT statement in peer-reviewed journals. Discussion This is one of the first larger randomised clinical trials evaluating the effect of a group-based intervention for adolescents with a

  18. [Current modalities and concepts on access and use of biospecimen samples and associated data for research from human biobanks].

    Science.gov (United States)

    Siddiqui, Roman; Semler, Sebastian Claudius

    2016-03-01

    It is accepted worldwide that biospecimen and data sharing (BDS) play an essential role for the future of medical research to improve diagnostics and prognostics, e.g. by validated biomarkers. BDS is also pivotal to the development of new therapeutic treatments and for the improvement of population health. Human biobanks can generate an added value to this need by providing biospecimens and/or associated data to researchers. An inspection of several examples of epidemiological as well as clinical/disease-oriented biobanks in Germany shows that best practice procedures (BPP) that are internationally agreed on are being installed for biospecimen and/or data access. In general, fair access is aimed at requiring a written application by the requesting scientist, which is then peer-reviewed for scientific and ethical validity by the Biobank. Applied BPP take into account (i) patient education/agreement according to the informed consent model, (ii) privacy protection, (iii) intellectual property rights, the (iv) notification obligation of health-related findings (including incidental findings), the (v) use of material (MTA) and data transfer agreements (DTA) for mutual legal security, the avoidance of conflicts of interests, as well as for cost recovery/fee for service as a basis for sustainability of the biobank. BPP are rooted in the self-regulation efforts of life sciences and are supported by parent ethics committees in Germany. Central biobank registries displaying aggregated information on biospecimens stored and the research foci constitute an important tool to make biobanks that are scattered across the country visible to each other, and, can thus promote access to hitherto unknown biospecimen and data resources. PMID:26809822

  19. Effects of high protein and balanced diets on lipid profiles and inflammation biomarkers in obese and overweight women at aerobic clubs: A randomized clinical trial

    Directory of Open Access Journals (Sweden)

    Pegah Amini

    2016-01-01

    Full Text Available Background: We studied the effects of high protein (HP and balanced diets (BDs on lipid profiles, and high-sensitive C-reactive protein (hs-CRP levels in obese and overweight women. Methods: In a parallel designed randomized controlled clinical trial, 60 healthy women with body mass index ≥25 kg/m 2 , aged 20-46 years, enrolled in an 8-week investigation at aerobic clubs. They were categorized into two groups (HP and BDs, randomly. Fasting lipid profile and hs-CRP levels were evaluated at the beginning and end of the trial. We assessed dietary intake by 3-day records and also used SPSS (version 18; SPSS Inc., Chicago, IL, USA for data analyzing. Results: Fifty-six participants completed the intervention. Concentrations of low-density lipoprotein cholesterol (P < 0.001 in BD group vs. P =0.023 in HP group and high-density lipoprotein cholesterol (P < 0.001 in BD group vs. P =0.002 in HP group increased significantly in both groups. Circulating triglycerides levels increased in both intervention grows, but the change in the HP group was not significant compared with the other group (P = 0.007 in BD group vs. P =0.099 in HP group. Whereas total cholesterol concentration decreased but not significantly so (P = 0.53 in BD group vs. P =0.73 in HP group. There were marginally significant decreases in the hs-CRP levels due to both diets (P = 0.057 in BD group vs. P =0.086 in HP group; however, there were no significant differences between the groups. Conclusions: Administration of HP and BD in overweight and obese women with regular aerobic exercise showed improvement in lipid profiles and hs-CRP levels within the groups, but there were no significant differences between groups.

  20. The clinical application of cystatin C, retinol binding protein and D-dimer in preeclampsia diagnosis%子痫前期患者胱抑素C、视黄醇结合蛋白、D-二聚体检测的临床应用研究

    Institute of Scientific and Technical Information of China (English)

    王艳春; 雒雪

    2016-01-01

    目的:探讨胱抑素C(cystatin C, CysC)、视黄醇结合蛋白(retinol binding protein, RBP)、D-二聚体(D-dimer, D-D)在子痫前期患者诊断中的临床应用价值。方法选取我院220例晚期妊娠住院的子痫前期患者为研究对象,分为轻度子痫前期组120例,重度子痫前期组100例,选择同期正常孕妇100例为对照组,检测所有受试者CysC、RBP及D-D的水平,对检测结果进行统计学分析。结果轻度子痫前期组、重度子痫前期组及对照组间CysC、RBP及D-D差异均有统计学意义(P均<0.05);轻度子痫前期组、重度子痫前期组CysC、RBP及D-D检测结果均高于对照组,且差异均具有统计学意义(P均<0.05);轻度子痫前期组CysC、RBP及D-D的检测结果均高于对照组,且差异均有统计学意义(P均<0.05)。结论 CysC、RBP及D-D在子痫前期病情严重程度评估方面有重要的临床参考意义。%Objective To study the clinical application value of cystatin C (CysC), retinol binding protein(RBP) and D-dimer(D-D) in preeclampsia diagnosis. Methods 220 cases patients with preeclamp-sia in our hospital from May 2015 to February 2016 were collected , and were divided into mild preeclampsia group(120 cases), severe preeclampsia group(100 cases). 100 cases normal pregnant women at the same pe-riod were collected as control group. The CysC, RBP and D-D levels of all the subjects were all detected, and the results were analyzed statistically. Results There were statistical significance in the differences of serum CysC, RBP and D-D levels among mild preeclampsia group, severe preeclampsia group and control group (Pall<0.05). The CysC, RBP and D-D levels in mild preeclampsia group and severe preeclampsia group were all higher than that of control group, and the differences all had statistical significance(Pall<0.05). The CysC, RBP and D-D levels in severe preeclampsia group were all

  1. Impact of Drought Stress on Germination of Sophora Alopecuroides and Swainsonia Salsula Seeds%苦豆子和苦马豆种子萌发对干旱胁迫的响应特征

    Institute of Scientific and Technical Information of China (English)

    张勇; 刘义; 颜霞; 鄂利锋; 王进

    2012-01-01

    以河西走廊中部荒漠边缘的苦豆子(Sophora alopecuroides L.)和苦马豆〔Swainsonia salsula(Pall.)DC.〕为材料,采用聚乙二醇PEG-6000模拟干旱条件,在6种渗透势(-0.03,-0.10,-0.24,-0.42,-0.65,-0.94 MPa)条件下对种子萌发和幼苗生长进行了研究。研究结果显示,随着干旱胁迫程度的加剧,两种植物种子吸胀速率、发芽率、发芽指数、生活力、苗高和根长、组织饱和含水量等指标均表现出明显降低的趋势,而幼苗干重、根干重和根冠比均呈先升后降的趋势。研究表明,苦豆子和苦马豆种子在适当的干旱胁迫下可以提高其幼苗的抗旱性,有利于培育壮苗。%The effects of drought stress,simulated using polyethylene glycol(PEG-6000)(-0.03,-0.10,-0.24,-0.42,-0.65,-0.94 MPa),were investigated on the germination of the seeds and the growth the seedlings of two plant species,Sophora alopecuroides L and Swainsonia salsula(Pall.) DC.which are dominant local species on the desert edge in the middle of Hexi Corridor.The results show that with increasing stress from PEG,water absorbing rate,germination percentage,germination index,vigorousness,seedling height,root length,and saturated water content of both species decreased,whereas dry weights of seedling and root,and crown-root ratio increased and then decreased.This indicates that appropriate drought stress might improve the drought resistance and then the quality of the seedlings.Possible causes for this adaptation to drought stress by the two species were explained and discussed.

  2. Particulate hot gas stream cleanup technical issues

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-09-01

    This is the eleventh in a series of quarterly reports describing the activities performed under Contract No. DE-AC21-94MC31160. Analyses of Hot Gas Stream Cleanup (HGCU) ashes and descriptions of filter performance address aspects of filter operation that are apparently linked to the characteristics of the collected ash or the performance of the ceramic bed filter elements. Task 1 is designed to generate a data base of the key characteristics of ashes collected from operating advanced particle filters (APFS) and to relate these ash properties to the operation and performance of these filters. Task 2 concerns testing and failure analysis of ceramic filter elements. Under Task 1 during the past quarter, analyses were completed on samples obtained during a site visit to the Power Systems Development Facility (PSDF). Analyses are in progress on ash samples from the Advanced Particulate Filter (APF) at the Pressurized Fluidized-Bed Combustor (PFBC) that was in operation at Tidd and ash samples from the Pressurized Circulating Fluid Bed (PCFB) system located at Karhula, Finland. An additional analysis was performed on a particulate sample from the Transport Reactor Demonstration Unit (TRDU) located at the University of North Dakota Energy and Environmental Research Center. A manuscript and poster were prepared for presentation at the Advanced Coal-Based Power and Environmental Systems `97 Conference scheduled for July 22 - 24, 1997. A summary of recent project work covering the mechanisms responsible for ash deposit consolidation and ash bridging in APF`s collecting PFB ash was prepared and presented at FETC-MGN in early July. The material presented at that meeting is included in the manuscript prepared for the Contractor`s Conference and also in this report. Task 2 work during the past quarter included mechanical testing and microstructural examination of Schumacher FT20 and Pall 326 as- manufactured, after 540 hr in service at Karhula, and after 1166 hr in service at

  3. Decontamination of wastewater containing persistent toxic compounds by combining solar photo catalysis and biological oxidation; Depuracion de aguas contaminadas con toxicos persistentes mediante combinacion de fotocatalisis solar y oxidacion biologica

    Energy Technology Data Exchange (ETDEWEB)

    Oller Alverola, I.; Sanchez Perez, J. A.; Malato Rodriguez, S.

    2008-07-01

    in the photo-Fenton process at which toxicity had gone down. The biological reactor used in this research is a fixed-bed reactor colonized by WWTP activated sludge fixed on polypropylene PallRing supports. The combination of the photo-Fenton and biological reactor treatment of the pesticides was successful, both in batch and continuous modes, achieving a maximum treatment capacity of 16 mg COD/h L Pall Ring (overall efficiency over 90%). In a later stage of research, this methodology for combining photo-Fenton and aerobic biological degradation was successfully applied to treatment of industrial saline waste water from a pharmaceutical plant. (Author)

  4. High-Performance Palladium Based Membrane for Hydrogen Separation and Purification

    Energy Technology Data Exchange (ETDEWEB)

    Hopkins, Scott

    2012-01-31

    The mission of the DOE's Fuel Cell Technologies'Hydrogen Fuels R&D effort is to research, develop, and validate technologies for producing, storing, and delivering hydrogen in an efficient, clean, safe, reliable, and affordable manner. A key program technical milestone for hydrogen technology readiness is to produce hydrogen from diverse, domestic resources at $2.00-$3.00 per gallon of gasoline equivalent (gge) delivered, untaxed. Low-cost, high-temperature hydrogen separation membranes represent a key enabling technology for small-scale distributed hydrogen production units. Availability of such membranes with high selectivity and high permeability for hydrogen will allow their integration with hydrocarbon reforming and water gas shift reactions, potentially reducing the cost of hydrogen produced. Pd-metal-based dense membranes are known for their excellent hydrogen selectivity and permeability characteristics, however, utilization of these membranes has so far been limited to small scale niche markets for hydrogen purification primarily due to the relatively high cost of Pd-alloy tubes compared to pressure swing adsorption (PSA) units. This project was aimed at development of thin-film Pd-alloy membranes deposited on Pall Corporation's DOE-based AccuSep® porous metal tube substrates to form a composite hydrogen separation membrane for these applications. Pall's composite membrane development addressed the typical limitations of composite structures by developing robust membranes capable of withstanding thermal and mechanical stresses resulting from high temperature (400C), high pressure (400 psi steam methane reformer and 1000 psi coal) operations and thermal cycling involved in conventional hydrogen production. In addition, the Pd-alloy membrane composition was optimized to be able to offer the most stability in the typical synthesis gas environments produced by reforming of natural gas and bio-derived liquid fuels (BILI) validating the

  5. Analysis on RAPD Fingerprints and Genetic Relationship of Astragalus Hybrid%黄芪杂交种RAPD指纹图谱及其亲缘关系分析

    Institute of Scientific and Technical Information of China (English)

    高霞; 赵景峰; 何为平; 马金星; 伊风艳

    2011-01-01

    In this study, the genetic relationship between the A.membranaceus Bunge,A.adsurgens Pall.and hybrids were analyzed by using RAPD fingerprints,and coefficient of genetic similarity were also studied.The results indicated that a specific band (P3-670) and 2 specific bands (P5-680,P5-870) could be amplified from the Astragalus hybrid by primer 3 and 5.While the paternal parent (A.membranaceus Bunge) and the maternal parent (A.adsurgens Pall.) had no specific bands.Primer 4 could produce a specific band ( about 730 bp) to A.membranaceus Bunge, but the other 5 materials had no specific band.Furthermore Astragalus hybrid had a small genetic similarity to its father, while had a big one to its mother.So the genetic characters of Astragalus hybrid were mostly come from its maternal parent.%对膜荚黄芪和斜茎黄芪及其杂交种(黄芪草),利用RAPD标记进行了指纹图谱及遗传相似系数分析.结果表明.黄芪草在引物P3和P5的扩增图谱中分别具有1条和2条特异带(P3-670、P5-680、P5-870).而父本膜荚黄芪与母本斜茎黄芪无此特异带;在引物P4的扩增下膜荚黄芪具有一条730 bp左右的特异带,而其余5份材料均未出现该特异带;黄芪草与其父本膜荚黄芪遗传相似系数较小,而与母本斜茎黄芪遗传相似系数较大,其遗传偏向母本.

  6. Danggui-Shaoyao-San: New Hope for Alzheimer's Disease.

    Science.gov (United States)

    Fu, Xin; Wang, QiuHong; Wang, ZhiBin; Kuang, HaiXue; Jiang, Pinghui

    2016-08-01

    Danggui-Shaoyao-San (DSS), also called Toki-shakuyaku-san (TJ-23) or Dangguijakyak-san (DJS), is a well-known herbal formula (Angelica sinensis (Oliv.) Diels., Ligusticum chuanxiong Hort., Paeonia lactiflora pall., Poria cocos (Schw.) Wolf, Alisma orientalis (Sam.) Juzep., Atractylodes macrocephala Koidz.), which has been widely used in oriental countries for the treatment of various gynecological diseases. Recent studies show that DSS has an effect on free radical-mediated neurological diseases and exhibits anti-inflammatory and antioxidant activities and reduces cell apoptosis in the hippocampus. In addition, DSS mediates the modulation of central monoamine neurotransmitter systems and ameliorates dysfunction of the central cholinergic nervous system and scopolamine-induced decrease in ACh levels. DSS improves the function of the dopaminergic, adrenergic, and serotonergic nervous systems. Interestingly, DSS can alleviate cognitive dysfunction of Alzheimer's disease (AD) patients, suggesting that it is a useful therapeutic agent for AD. This paper reviews the mechanism of DSS for the treatment of AD. PMID:27493835

  7. The Effects of Refraction on Transit Transmission Spectroscopy: Application to Earth-like Exoplanets

    CERN Document Server

    Misra, Amit; Crisp, Dave

    2014-01-01

    We quantify the effects of refraction in transit transmission spectroscopy on spectral absorption features and on temporal variations that could be used to obtain altitude-dependent spectra for planets orbiting stars of different stellar types. We validate our model against altitude-dependent transmission spectra of the Earth from ATMOS and against lunar eclipse spectra from Palle et al. (2009). We perform detectability studies to show the potential effects of refraction on hypothetical observations of Earth analogs with the James Webb Space Telescope (JWST) Near-Infrared Spectrograph (NIRSPEC). Due to refraction, there will be a maximum tangent pressure level that can be probed during transit for each given planet-star system. We show that because of refraction, for an Earth-analog planet orbiting in the habitable zone of a Sun-like star only the top 0.3 bars of the atmosphere can be probed, leading to a decrease in the signal to noise ratio (SNR) of absorption features by 60%, while for an Earth-analog plan...

  8. Evaluation of Alternative Filter Media for the Rotary Microfilter

    International Nuclear Information System (INIS)

    The Savannah River Site is currently developing and testing several processes to treat high level radioactive liquid waste. Each of these processes has a solid-liquid separation process that limits its throughput. Savannah River National Laboratory researchers identified and tested the rotary microfilter as a technology to increase solid-liquid separation throughput. The authors believe the rotary microfilter throughput can be improved by using a better filter membrane. Previous testing showed that asymmetric filters composed of a ceramic membrane on top of a stainless steel support produced higher filter flux than 100% stainless steel symmetric filters in crossflow filter tests. Savannah River National Laboratory and Oak Ridge National Laboratory are working together to develop asymmetric ceramic-stainless steel composite filters and asymmetric 100% stainless steel filters to improve the throughput of the rotary microfilter. The Oak Ridge National Laboratory Inorganic Membrane Group fabricated samples of alternative filter membranes. In addition, Savannah River National Laboratory obtained samples of filter membranes from Pall, Porvair, and SpinTek. They tested these samples in a static test cell with feed slurries containing monosodium titanate and simulated sludge

  9. Differential Responses to Simulated Precipitation Exhibited by a Typical Shrub and a Herb Coexisted in Hunshandak Sandy Land

    Institute of Scientific and Technical Information of China (English)

    NIUShu-Li; PENGYu; JIANGGao-Ming; LIYong-Geng; GAOLei-Ming; LIUMei-Zhen; CUIHong-Xia; DINGLi

    2004-01-01

    To assess the ecophysiological responses and adaptive strategies to rainfall exhibited by different plant functional types, we compared gas exchange, leaf water potential (ψleaf) and PS photochemical efficiency (Fv/Fm) between Hedysarum fruticosum Pall. (shrub) and Salsola collina Y. L. Chang(herb) under a series of simulated rainfalls. The experiment was conducted in Hunshandak Sandy Land, North China. The values of net photosynthetic rate (Pn), transpiration rate (E), stomatal conductance (gs), Fv/Fm and ψleaf always elevated with the increasing amount of simulated rainfall. Whereas water useefficiency (WUE) maintained constant in H. fruticosum while always decreased in S.collina. Both speciesfully recovered their Pn and Fv/Fm 3d after rainfall, while gs and ψleaf recovered only within 2 d. However, the response patterns were obviously different. H.fruticosu promote its physiological traits within 5-15 mm rainfall but no further positive enhancement was noted when rainfall was larger than 15 mm. In S.collina, however, the enhancement continued with more water applied. We inferred that H.fruticosum and S.collina responded similarly to rainfall in time courses but differential to simulated precipitation change. S.collina was likely to be physiologically sensitive to instant increasing soil water, that can be regarded as a prodigal water use type; whilst H.fruticosum was a conservative water user.

  10. Theoretical considerations about a membrane process for helium purification in multichannel monoliths for high temperature nuclear reactors

    International Nuclear Information System (INIS)

    Highlights: ► Modeling and simulation of helium purification in HTR. ► Membrane separation process for helium purification. ► Microporous silica membrane on multichannel monolith support. ► Effect of thick porous support on gas separation process. ► New cascade configuration of membrane modules for optimized purification. - Abstract: In this work we present the modeling and simulation of a new membrane process for helium purification in high temperature nuclear reactors. We considered the application of multichannel porous monolith supports from Pall-Exekia, with thin, microporous layers of silica/alumina. These membranes present helium permeance values in the range of 10−10 kmol m−2 s−1 Pa−1 at 300 °C for transmembrane pressures of 1–60 bar. The Dusty Gas Model was used in order to highlight the effect of the porous support on the separation. An original new cascade configuration has been designed to reach the desired range of helium purity. Simulations showed many advantages of this configuration over those previously reported in the bibliography because there are no recycles and no intermediate compression units.

  11. Characterization of the Anti-Influenza Activity of the Chinese Herbal Plant Paeonia lactiflora

    Directory of Open Access Journals (Sweden)

    Jin-Yuan Ho

    2014-04-01

    Full Text Available Bai Shao (BS, the root of Paeonia lactiflora Pall., a common Chinese herb in many recipes used to treat viral infection and liver diseases, is recognized for its ability to nourish menstruation, its Yin convergence, and as an antiperspirant. However, the mechanism and components for its antiviral function remain to be elucidated. In this study, an ethanolic extract of BS was further partitioned into aqueous and organic parts (EAex for in vitro functional study and in vivo efficacy testing. EAex exhibited an IC50 of 0.016 ± 0.005 mg/mL against influenza virus A/WSN/33 (H1N1, with broad-spectrum inhibitory activity against different strains of human influenza A viruses, including clinical oseltamivir-resistant isolates and an H1N1pdm strain. The synthesis of both viral RNA and protein was profoundly inhibited when the cells were treated with EAex. A time-of-addition assay demonstrated that EAex exerted its antiviral activity at various stages of the virus replication cycle. We addressed its antiviral activity at virus entry and demonstrated that EAex inhibits viral hemagglutination and viral binding to and penetration into host cells. In vivo animal testing showed that 200 mg/kg/d of EAex offered significant protection against viral infection. We conclude that BS possesses antiviral activity and has the potential for development as an anti-influenza agent.

  12. HPP Boshkov Most - upgrading of the design installed capacity from 45 MW to 70 MW

    International Nuclear Information System (INIS)

    HPP Boshkov Most location will be near the town of Debar, accessible from Mavrovo-Debar road. This procject involves the tributaries that combine to make up the Mala Reka, the biggest tributary to Radika river. The watershed area is characterized as having high mountains and rich watercourses, without major settlements. The hydro system consists of: The Tresonche reservoir with 44 m high dam, with an intake to head race tunnel, also additional intakes linked by a system siphons, covered channels collect the waters from high mountains and deliver their flow to the head race tunnel. The head race tunnel ends with surge shaft and penstocks to the powerhouse. In this paper will be given differences between the Main Design prepared by HEP - Skopje in 1983, where the installed capacity is 45 MW and feasibility Study prepared by Pall C. Rizzo Ass., where installed capacity is suggested to be 70 MW, thru enlarged nominal discharge - from 14 m3/s to 22 m3/s. (Author)

  13. 连续蒸馏塔在回收糖精废液中甲醇的应用%Application of the Continuous Rectification Column in Recovering Methyl Alcohol From Saccharin Waste Liquid

    Institute of Scientific and Technical Information of China (English)

    祝新红

    2011-01-01

    介绍了连续蒸馏塔在回收糖精废液中甲醇的应用,并采用了直接蒸汽加热、蒸发式冷凝器、金属丝网填料和鲍尔环配合使用等新工艺,解决了提留段的堵塞问题,冷却时需大量循环水,电耗高等一系列问题,降低了糖精生产中的甲醇消耗,取得了良好的社会效益和经济效益.%Application of the continuous rectification column in recovering methyl alcohol from saccharin waste liquid was introduced. Some new techniques including direct steam heating, evaporative condenser, metal wire packing and pall ring were used to solve a series of problems, such as stripping section blockage, massive circulating water demand during cooling, high power consumption and so on. At the same time, the methyl alcohol consumption in the saccharin production was lowered ,and good social efficiency and economic efficiency were obtained.

  14. Laboratory and Simulated Field Bioassays to Evaluate Larvicidal Activity of Pinus densiflora Hydrodistillate, Its Constituents and Structurally Related Compounds against Aedes albopictus, Aedes aegypti and Culex pipiens pallens in Relation to Their Inhibitory Effects on Acetylcholinesterase Activity.

    Science.gov (United States)

    Lee, Dong Chan; Ahn, Young-Joon

    2013-01-01

    The toxicity of Pinus densiflora (red pine) hydrodistillate, its 19 constituents and 28 structurally related compounds against early third-instar larvae of Aedes albopictus (Ae. albopictus), Aedes aegypti (Ae. aegypti) and Culex pipiens palles (Cx. p. pallens) was examined using direct-contact bioassays. The efficacy of active compounds was further evaluated in semi-field bioassays using field-collected larval Cx. p. pallens. Results were compared with those of two synthetic larvicides, temephos and fenthion. In laboratory bioassays, Pinus densiflora hydrodistillate was found to have 24 h LC50 values of 20.33, 21.01 and 22.36 mg/L against larval Ae. albopictus, Ae. aegypti and Cx. p. pallens respectively. Among the identified compounds, thymol, δ-3-carene and (+)-limonene exhibited the highest toxicity against all three mosquito species. These active compounds were found to be nearly equally effective in field trials as well. In vitro bioassays were conducted to examine the acetylcholinesterase (AChE) inhibitory activity of 10 selected compounds. Results showed that there is a noticeable correlation between larvicidal activity and AChE inhibitory activity. In light of global efforts to find alternatives for currently used insecticides against disease vector mosquitoes, Pinus densiflora hydrodistillate and its constituents merit further research as potential mosquito larvicides.

  15. Laboratory and Simulated Field Bioassays to Evaluate Larvicidal Activity of Pinus densiflora Hydrodistillate, Its Constituents and Structurally Related Compounds against Aedes albopictus, Aedes aegypti and Culex pipiens pallens in Relation to Their Inhibitory Effects on Acetylcholinesterase Activity

    Directory of Open Access Journals (Sweden)

    Young-Joon Ahn

    2013-05-01

    Full Text Available The toxicity of Pinus densiflora (red pine hydrodistillate, its 19 constituents and 28 structurally related compounds against early third-instar larvae of Aedes albopictus (Ae. albopictus, Aedes aegypti (Ae. aegypti and Culex pipiens palles (Cx. p. pallens was examined using direct-contact bioassays. The efficacy of active compounds was further evaluated in semi-field bioassays using field-collected larval Cx. p. pallens. Results were compared with those of two synthetic larvicides, temephos and fenthion. In laboratory bioassays, Pinus densiflora hydrodistillate was found to have 24 h LC50 values of 20.33, 21.01 and 22.36 mg/L against larval Ae. albopictus, Ae. aegypti and Cx. p. pallens respectively. Among the identified compounds, thymol, δ-3-carene and (+-limonene exhibited the highest toxicity against all three mosquito species. These active compounds were found to be nearly equally effective in field trials as well. In vitro bioassays were conducted to examine the acetylcholinesterase (AChE inhibitory activity of 10 selected compounds. Results showed that there is a noticeable correlation between larvicidal activity and AChE inhibitory activity. In light of global efforts to find alternatives for currently used insecticides against disease vector mosquitoes, Pinus densiflora hydrodistillate and its constituents merit further research as potential mosquito larvicides.

  16. Laboratory and Simulated Field Bioassays to Evaluate Larvicidal Activity of Pinus densiflora Hydrodistillate, Its Constituents and Structurally Related Compounds against Aedes albopictus, Aedes aegypti and Culex pipiens pallens in Relation to Their Inhibitory Effects on Acetylcholinesterase Activity.

    Science.gov (United States)

    Lee, Dong Chan; Ahn, Young-Joon

    2013-01-01

    The toxicity of Pinus densiflora (red pine) hydrodistillate, its 19 constituents and 28 structurally related compounds against early third-instar larvae of Aedes albopictus (Ae. albopictus), Aedes aegypti (Ae. aegypti) and Culex pipiens palles (Cx. p. pallens) was examined using direct-contact bioassays. The efficacy of active compounds was further evaluated in semi-field bioassays using field-collected larval Cx. p. pallens. Results were compared with those of two synthetic larvicides, temephos and fenthion. In laboratory bioassays, Pinus densiflora hydrodistillate was found to have 24 h LC50 values of 20.33, 21.01 and 22.36 mg/L against larval Ae. albopictus, Ae. aegypti and Cx. p. pallens respectively. Among the identified compounds, thymol, δ-3-carene and (+)-limonene exhibited the highest toxicity against all three mosquito species. These active compounds were found to be nearly equally effective in field trials as well. In vitro bioassays were conducted to examine the acetylcholinesterase (AChE) inhibitory activity of 10 selected compounds. Results showed that there is a noticeable correlation between larvicidal activity and AChE inhibitory activity. In light of global efforts to find alternatives for currently used insecticides against disease vector mosquitoes, Pinus densiflora hydrodistillate and its constituents merit further research as potential mosquito larvicides. PMID:26464387

  17. Process-Costing, Job-Order-Costing, Operation Costing (også kaldet Batch Costing og Functional Costing - Når Systemtankegangen ligger til grund for økonomistyringen og dens beslutninger)

    DEFF Research Database (Denmark)

    Nielsen, Steen

    2005-01-01

    ordreregnskabet, f.eks. som dette er analyseret hos Palle Hansen og Vagn Madsen. Begrebet operational costing anvendes også, men dette dækker i realiteten over, hvordan og hvilke elementer der indgår i hele virksomhedens regnskabs-information-system. Dvs. at dette mere er et spørgsmål om, hvordan systemerne er......De tre begreber process-costing, job-order-costing, operation-costing samt functional-based costing er faktisk historiske begreber som stammer langt tilbage i økonomistyringslitteraturen, faktisk tilbage til Scientific Management bevægelsen fra 20'erne og 30'erne. Man kan derfor ikke sige, at disse...... Aktivitets-Baseret Cost Management systemerne. Det er derfor vigtigt dels at kende sin historie på området, dels at gøre sig klart, om de under visse antagelser stadig har deres berettigelse. De samme begreber har også deres pendant til de danske begreber, afdelings- eller funktionsregnskabet samt...

  18. Cloning of vacuolar H+-ATPase subunit c genes from Japanese iris, and functional characterization in yeast

    Institute of Scientific and Technical Information of China (English)

    ZHOU Ai-min; WU Duo; CHE Dai-di; LIU Shen-kui; YANG Chuan-ping; WANG Jin-gang

    2011-01-01

    Five different isoforms (IrlVHA-cl-c5) of V-ATPase subunit c(VHA-c) were cloned from a Japanese iris (Iris lactea Pall. Var. chinensisFisch. Koidz) cDNA library using degenerate primers PCR and the5'-RACE technique. The sequence analysis showed the open readingframe (ORF) of the IrlVHA-c1-c5 to be 495 bp, corresponding to a pro-tein of 164 amino acids. Among the five isoforms, IrlVHA-c1 andIrlVHA-c2 are completely homologous. The IrlVHA-c protein is localizedat the vacuolar membrane as indicated by a green fluorescent protein(GFP) marker. Its over-expression in yeast could enhance yeast toleranceto NaCl stress. These results show that there are at least five genes en-coding different isoforms of IrlVHA-c in Japanese iris and IrlVHA-c isimportant for the function of V-ATPase.

  19. Stabilization of Fast Pyrolysis Oil: Post Processing Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Elliott, Douglas C.; Lee, Suh-Jane; Hart, Todd R.

    2012-03-01

    UOP LLC, a Honeywell Company, assembled a comprehensive team for a two-year project to demonstrate innovative methods for the stabilization of pyrolysis oil in accordance with DOE Funding Opportunity Announcement (FOA) DE-PS36-08GO98018, Biomass Fast Pyrolysis Oil (Bio-oil) Stabilization. In collaboration with NREL, PNNL, the USDA Agricultural Research Service (ARS), Pall Fuels and Chemicals, and Ensyn Corporation, UOP developed solutions to the key technical challenges outlined in the FOA. The UOP team proposed a multi-track technical approach for pyrolysis oil stabilization. Conceptually, methods for pyrolysis oil stabilization can be employed during one or both of two stages: (1) during the pyrolysis process (In Process); or (2) after condensation of the resulting vapor (Post-Process). Stabilization methods fall into two distinct classes: those that modify the chemical composition of the pyrolysis oil, making it less reactive; and those that remove destabilizing components from the pyrolysis oil. During the project, the team investigated methods from both classes that were suitable for application in each stage of the pyrolysis process. The post processing stabilization effort performed at PNNL is described in this report. The effort reported here was performed under a CRADA between PNNL and UOP, which was effective on March 13, 2009, for 2 years and was subsequently modified March 8, 2011, to extend the term to December 31, 2011.

  20. Comparison of Paeoniflorin and Albiflorin on Human CYP3A4 and CYP2D6

    Directory of Open Access Journals (Sweden)

    Li-Na Gao

    2015-01-01

    Full Text Available Peony (Paeonia lactiflora Pall- is a plant medicine and a functional food ingredient with wide application for more than 2000 years. It can be coadministrated with many other drugs, composed of traditional Chinese medicine compound such as shaoyao-gancao decoction. In order to explore the efficacy and safety of peony, effects of paeoniflorin and albiflorin (the principal components of peony on cytochrome P450 (CYP 3A4 and CYP2D6 were analyzed in human hepatoma HepG2 cells and evaluated from the level of recombinant CYP enzymes in vitro. The findings indicated that albiflorin possessed stronger regulation on the mRNA expression of CYP3A4 and CYP2D6 than paeoniflorin. For the protein level of CYP3A4, albiflorin showed significant induction or inhibition with the concentration increasing from 10−7 M to 10−5 M, but no remarkable variation was observed in paeoniflorin-treated group. Enzyme activity assay implied that both paeoniflorin and albiflorin could regulate CYP3A4 and CYP2D6 with varying degrees. The results showed that albiflorin should be given more attention because it may play a vital role on the overall efficacy of peony. The whole behavior of both paeoniflorin and albiflorin should be focused on ensuring the rationality and effectiveness of clinical application.

  1. Identification of 1,2,3,4,6-Penta-O-galloyl-β-d-glucopyranoside as a Glycine N-Methyltransferase Enhancer by High-Throughput Screening of Natural Products Inhibits Hepatocellular Carcinoma.

    Science.gov (United States)

    Kant, Rajni; Yen, Chia-Hung; Lu, Chung-Kuang; Lin, Ying-Chi; Li, Jih-Heng; Chen, Yi-Ming Arthur

    2016-01-01

    Glycine N-methyltransferase (GNMT) expression is vastly downregulated in hepatocellular carcinomas (HCC). High rates of GNMT knockout mice developed HCC, while overexpression of GNMT prevented aflatoxin-induced carcinogenicity and inhibited liver cancer cell proliferation. Therefore, in this study, we aimed for the identification of a GNMT inducer for HCC therapy. We established a GNMT promoter-driven luciferase reporter assay as a drug screening platform. Screening of 324 pure compounds and 480 crude extracts from Chinese medicinal herbs resulted in the identification of Paeonia lactiflora Pall (PL) extract and the active component 1,2,3,4,6-penta-O-galloyl-β-d-glucopyranoside (PGG) as a GNMT inducer. Purified PL extract and PGG induced GNMT mRNA and protein expression in Huh7 human hepatoma cells and in xenograft tumors. PGG and PL extract had potent anti-HCC effects both in vitro and in vivo. Furthermore, PGG treatment induced apoptosis in Huh7 cells. Moreover, PGG treatment sensitized Huh7 cells to sorafenib treatment. Therefore, these results indicated that identifying a GNMT enhancer using the GNMT promoter-based assay might be a useful approach to find drugs for HCC. These data also suggested that PGG has therapeutic potential for the treatment of HCC. PMID:27153064

  2. Identification of 1,2,3,4,6-Penta-O-galloyl-β-d-glucopyranoside as a Glycine N-Methyltransferase Enhancer by High-Throughput Screening of Natural Products Inhibits Hepatocellular Carcinoma

    Directory of Open Access Journals (Sweden)

    Rajni Kant

    2016-05-01

    Full Text Available Glycine N-methyltransferase (GNMT expression is vastly downregulated in hepatocellular carcinomas (HCC. High rates of GNMT knockout mice developed HCC, while overexpression of GNMT prevented aflatoxin-induced carcinogenicity and inhibited liver cancer cell proliferation. Therefore, in this study, we aimed for the identification of a GNMT inducer for HCC therapy. We established a GNMT promoter-driven luciferase reporter assay as a drug screening platform. Screening of 324 pure compounds and 480 crude extracts from Chinese medicinal herbs resulted in the identification of Paeonia lactiflora Pall (PL extract and the active component 1,2,3,4,6-penta-O-galloyl-β-d-glucopyranoside (PGG as a GNMT inducer. Purified PL extract and PGG induced GNMT mRNA and protein expression in Huh7 human hepatoma cells and in xenograft tumors. PGG and PL extract had potent anti-HCC effects both in vitro and in vivo. Furthermore, PGG treatment induced apoptosis in Huh7 cells. Moreover, PGG treatment sensitized Huh7 cells to sorafenib treatment. Therefore, these results indicated that identifying a GNMT enhancer using the GNMT promoter-based assay might be a useful approach to find drugs for HCC. These data also suggested that PGG has therapeutic potential for the treatment of HCC.

  3. Clinical value of combined detection of different tumor markers in patients with primary liver cancer%不同肿瘤标志物联合检测对原发性肝癌诊断的临床价值

    Institute of Scientific and Technical Information of China (English)

    陈英杰

    2015-01-01

    -L-fucosidase (AFU), alpha-fetoprotein (AFP), gamma-glu-tamyl transpeptidase (GGT) and carbohydrate antigen 50 (CA50) in the three groups were compared. The ac-curacy, sensitivity and specificity of 4 kinds of tumor markers in alone and combined detection in diagnosis of primary liver cancer were analyzed. Results There were statistical significance in the differences of AFU , AFP, GGT and CA50 levels among primary liver cancer group, hepatic benign lesions group and the control group (Pall<0.05). The AFU, AFP, GGT and CA50 levels in primary liver cancer group were all higher than that of hepatic benign lesions group and control group , the AFU, AFP, GGT and CA50 levels in hepatic be-nign lesions group were all higher than that of control group, and the differences all had statistical significance (Pall<0.05). The positive rates of single index and combined detection of primary liver cancer group were all higher than that of hepatic benign lesions, and the differences all had statistical significance (Pall<0.05). The positive rate of combined detection of primary liver cancer group was significantly higher than that of single in-dex (Pall<0.05). The area under receiver operating characteristic curve of AFU, AFP, GGT, CA50 and com-bined detection in diagnosing primary liver cancer were 0.867, 0.774, 0.742, 0.704, 0.984. The diagnosis a-bility of combined detection was higher than that of single index , and the sensitivity was 94.12%, specificity was 87.50%, Youden index was 0.82. Conclusion Combined detection of AFU, AFP, GGT and CA50 can improve the accuracy of primary liver cancer diagnosing.

  4. Determination of antioxidant effects of some plant species wild growing in Turkey.

    Science.gov (United States)

    Serteser, Ahmet; Kargioğlu, Mustafa; Gök, Veli; Bağci, Yavuz; Ozcan, Mehmet Musa; Arslan, Derya

    2008-01-01

    In this study, the antioxidant activity of 50% aqueous methanol extracts of Crataegus tanacetifolia (Lam.) Pers, Crataegus bornmuelleri Zaberi, Crataegus orientalis Pall. ex M.Bieb. var. orientalis, Crataegus szovitsii Pojark, Crataegus curvisepala Lindm., Crataegus monogyna Jacq. subsp. monogyna, Crataegus monogyna Jacq.subsp. azarella (Gris.) Franco, Crataegus micophylla C.Koch, Rosa foetida Herrm., Rosa hemisphaerica J.Herrm., Rosa pulverulenta M.Bieb., Rosa canina L., Rubus discolor Weihe & Nees, Rubus canescens DC. var. canescens, Rubus sanctus Screber, Rubus caesius L., Sorbus umbellata (Desf.) Fritsch var. umbellata, Prunus avium L. (Moench.) and Prunus cerasus L. Mespilus germenica was evaluated by various antioxidant assays, including free radical scavenging, hydrogen peroxide scavenging and metal-chelating activities. The extracts of R. hemisphaerica J.Herrm., P. cerasus L. and R. canina L. showed more stronger free radical scavenging and hydrogen peroxide scavenging activities, and the extracts of R. foetida Herrm. (62.54%) and P. cerasus L. showed stronger metal-chelating activity. The results obtained in the present study indicated that the R. hemisphaerica J.Herrm., P. cerasus L. and R. canina are potential sources of natural antioxidant. These antioxidant properties depend on the concentration of the sample. PMID:19382350

  5. Performance evaluation of biofilters and biotrickling filters in odor control of n-butyric acid.

    Science.gov (United States)

    Ding, Ying; Han, Zhiying; Wu, Weixiang; Shi, Dezhi; Chen, Yingxu; Li, Wenhong

    2011-01-01

    With the rapid development of swine production in China, odor pollution associated with piggery facilities has become an increasing environmental concern. N-butyric acid (n-BA) is one of the key odor compounds selected to represent volatile fatty acids (VFAs) found in piggery facilities. In this study, two biofilters (BFs) packed with compost (BFC) or sludge (BFS) and two biotrickling filters (BTFs) packed with pall rings (BTFP) or multidimensional hollow balls (BTFM), respectively, were compared with regard to their performances in the removal of n-BA. The non-biological removal capacities of packing material of the bioreactors on a per unit volume basis were BFS>BFC>BTFM>BTFP. Maximum biological removal capacities per unit volume of packing material of the bioreactors all exceeded 9.1 kg/m(3)·d and in the order of BFC>BTFM>BFS>BTFP. Kinetic analysis as well as overall evaluation by radar graphs showed that the BTFs achieved superior removal rates to the BFs in the order of BTFM>BTFP>BFC>BFS. The biotrickling filter packed with multidimensional hollow balls could be an effective technology for VFAs removal. Results from this research provide economical and effective alternatives for odor control in piggery facilities.

  6. 中国新疆石竹属一新种%A New Species of the Genus Dianthus from Xinjiang,China

    Institute of Scientific and Technical Information of China (English)

    董连新; 杨昌友; 王明庥; 黄敏仁; 蔡友铭

    2008-01-01

    描述了在新疆阿尔泰山喀纳斯自然保护区发现的石竹科(Caryophyllaceae)石竹属(Dianthus)植物一新种--阿尔泰石竹(Dianthus altaicus L.X.Dong & C.Y.Yang),并描绘了形态图.该新种与多分枝石竹(Dianthus ramosissimus Pall)相近,区别点在于:阿尔泰石竹(新种)的花冠粉红色,花瓣菱形,边缘无锯齿,光滑无毛,基生叶线形丛生如禾草状;花粉圆球形,外壁具刺状和环状纹饰;种子呈菱形,种皮表面具瘤状突起.并简单介绍了阿尔泰石竹的生境以及该种在阿尔泰山居群的大小和保护状况.

  7. Analysis of genetic diversity and population structure of Chinese yak breeds (Bos grunniens) using microsatellite markers

    Institute of Scientific and Technical Information of China (English)

    Guixiang Zhang; Weisheng Chen; Ming Xue; Zhigang Wang; Hong Chang; Xu Han; Xinjun Liao; Donglei Wang

    2008-01-01

    Nine Chinese yak breeds (Maiwa,Tianzhu White,Qinghai Plateau,Sibu,Zhongdian,Pall,Tibetan High Mountain,Jiulong,and Xin-jiang) and Gayal were analyzed by means of 16 microsatellite markers to determine the level of genetic variation within populations,genetic relationship between populations,and population structure for each breed.A total of 206 microsatellite alleles were observed.Mean F-statistics (0.056) for 9 yak breeds indicated that 94.4% of the genetic variation was observed within yak breeds and 5.6% of the genetic variation existed amongst breeds.The Neighbor-Joining phylogenetic free was constructed based on Nei's standard genetic dis-tances and two clusters were obtained.The Gayal separated from the yaks far away and formed one cluster and 9 yak breeds were grouped together.The analysis of population structure for 9 yak breeds and the Gayal showed that they resulted in four clusters; one clus-ter includes yaks from Tibet Autonomous Region and Qinghai Province,one cluster combines Zhongdian,Maiwa,and Tianzhu White,and Jiulong and Xinjiang come into the third cluster.Pali was mainly in the first cluster (90%),Jiulong was mainly in the second cluster (87.1%),Zhongdian was primarily in the third cluster (83%),and the other yak breeds were distributed in two to three clusters.The Gayal was positively left in the fourth cluster (99.3%).

  8. Soil carbon sequestration by three perennial legume pastures is greater in deeper soil layers than in the surface soil

    Science.gov (United States)

    Guan, X.-K.; Turner, N. C.; Song, L.; Gu, Y.-J.; Wang, T.-C.; Li, F.-M.

    2016-01-01

    Soil organic carbon (SOC) plays a vital role as both a sink for and source of atmospheric carbon. Revegetation of degraded arable land in China is expected to increase soil carbon sequestration, but the role of perennial legumes on soil carbon stocks in semiarid areas has not been quantified. In this study, we assessed the effect of alfalfa (Medicago sativa L.) and two locally adapted forage legumes, bush clover (Lespedeza davurica S.) and milk vetch (Astragalus adsurgens Pall.) on the SOC concentration and SOC stock accumulated annually over a 2 m soil profile. The results showed that the concentration of SOC in the bare soil decreased slightly over the 7 years, while 7 years of legume growth substantially increased the concentration of SOC over the 0-2.0 m soil depth. Over the 7-year growth period the SOC stocks increased by 24.1, 19.9 and 14.6 Mg C ha-1 under the alfalfa, bush clover and milk vetch stands, respectively, and decreased by 4.2 Mg C ha-1 in the bare soil. The sequestration of SOC in the 1-2 m depth of the soil accounted for 79, 68 and 74 % of the SOC sequestered in the 2 m deep soil profile under alfalfa, bush clover and milk vetch, respectively. Conversion of arable land to perennial legume pasture resulted in a significant increase in SOC, particularly at soil depths below 1 m.

  9. Podavač palet svislého obráběcího centra.

    OpenAIRE

    Krenželok, Andrzej

    2010-01-01

    Předmětem této diplomové práce je návrh konstrukčního řešení přenašeče palet svislého obráběcího centra. Přenašeč slouží k manipulaci s technologickými paletami mezi odkládacími místy obráběcích center a zásobníkem palet. Díky tomuto přenašeči stroje sdílejí jednu obrobkovou základnu. Hlavní důraz je kladen nejen na funkčnost, ale také na nízkou cenu řešení. The subject of this thesis is the proposal of constructional solution for pallet changer of the vertical machining center. This palle...

  10. 塞北紫堇化学成分的研究%Research on Chemical Constituents of SaiBei ZiJin

    Institute of Scientific and Technical Information of China (English)

    李怀平; 马斌; 任松鹏; 李丽

    2015-01-01

    目的:对塞北紫堇的化学成分进行研究。方法:通过硅胶柱层析和重结晶法进行分离,根据理化性质及ID-NMR、ESI-MS等波谱方法进行结构鉴定。结果:从塞北紫堇中共分离得到5种生物碱类单体化合物,分别为:α-比枯枯灵、原阿片碱、黄紫堇明碱、β-hydrastine、β-比枯枯灵。结论:α-比枯枯灵、原阿片碱、β-hydrastine为首次从该药材分离得到。%Objective: To study chemical constituents of SaiBei ZiJin [Corydalis impatiens (pall.) Fisch.]. Methods:SaiBei ZiJin was abstracted by silica column chromatography method and recrystalization method, struc-ture identification were performed according to physicochemical property, ID-NMR, ESI-MS and other spectral methods. Results: Five alkaloid monomer compounds were extracted from SaiBei ZiJin, they were: α-bicuculline, protopine, ochotensimine,β-hydrastine andβ-bicuculline. Conclusion:α-bicuculline, protopine andβ-hydrastine are isolated from medicinal materials for the first time.

  11. Effects of Seedbed Density on Seedling Morphological Characteristics of four Broadleaved Species

    Energy Technology Data Exchange (ETDEWEB)

    Yucedag, C.; Gailing, O.

    2012-11-01

    The aim of this study was to investigate the effects of seedling spacing on morphological characteristics of one year-old Amygdalus communis L., Prunus avium L., Pyrus elaeagnifolia Pall. and Eriolobus trilobatus (Poiret) Roemer seedlings under nursery conditions. Seedlings were grown in completely randomized blocks with four replications. Seedbeds were 1.2 m wide with 5 rows each 20 cm apart. Within-row spacings were chosen as 4, 8 and 12 cm to analyze the effect of seedlings density on growth performance. Seedling spacing significantly affected root collar diameter, shoot height, tap root length and number of fine roots in A. communis and P. avium, but not in P. elaeagnifolia and E. tribolatus. Additionally wider seedling spacings resulted in larger seedlings in A. communis and P. avium. In conclusion, it would be beneficial to use wider seedling spacing in order to obtain better seedling growth in A. communis and P. avium. Larger seedlings could also provide significant advantages because of reduced cultural activities and an expected higher growth and survival rate. (Author) 27 refs.

  12. Validation testing of radioactive waste drum filter vents

    Energy Technology Data Exchange (ETDEWEB)

    Weber, L.D. [Pall Corp., Port Washington, NY (United States); Rahimi, R.S. [Pall Corp., Cortland, NY (United States); Edling, D. [Edling & Associates, Inc., Russel Springs, KY (United States)

    1997-08-01

    The minimum requirements for Drum Filter Vents (DFVs) can be met by demonstrating conformance with the Waste Isolation Pilot Plant (WIPP) Trupact II Safety Assessment Report (SAR), and conformance with U.S. Federal shipping regulations 49 CFR 178.350, DOT Spec 7A, for Type A packages. These together address a number of safety related performance parameters such as hydrogen diffusivity, flow related pressure drop, filtration efficiency and, separately, mechanical stability and the ability to prevent liquid water in-leakage. In order to make all metal DFV technology (including metallic filter medium) available to DOE sites, Pall launched a product development program to validate an all metal design to meet these requirements. Numerous problems experienced by DOE sites in the past came to light during this development program. They led us to explore enhancements to DFV design and performance testing addressing these difficulties and concerns. The result is a patented all metal DFV certified to all applicable regulatory requirements, which for the first time solves operational and health safety problems reported by DOE site personnel but not addressed by previous DFV`s. The new technology facilitates operations (such as manual, automated and semi-automated drum handling/redrumming), sampling, on-site storage, and shipping. At the same time, it upgrades filtration efficiency in configurations documented to maintain filter efficiency following mechanical stress. 2 refs., 2 figs., 10 tabs.

  13. [Use of leukocyte-filtered, cytomegalovirus-antibody negative and irradiated cellular blood products].

    Science.gov (United States)

    Solheim, B G; Albrechtsen, D H; Evensen, S A; Leivestad, T

    1990-01-10

    This paper presents both quality requirements and indications for use of leucocyte-filtered, cytomegalovirus antibody negative and irradiated cellular blood products at Rikshospitalet. Emphasis is placed on the use of standardized buffycoat depleted red cells or platelet concentrates for filtration, and the selection of leucocyte filters with high capacity and ease of bedside application. Leucocyte counts as low as 1-2 10(5) per unit are recommended after filtration in order to avoid HLA-antibody production. For bedside filtration, our choice was RC100 and PL100 (Pall) for red cells and platelets respectively. For laboratory use we prefer, for economic reasons, to use Sepacell R500 (Asahi) and Imugard IG500 (Terumo) for red cells and platelets respectively. Leucocyte-filtered blood products are considered indicated in all pre-transplant transfusions, in post-transplant HLA-sensitized patients, in other patients with febrile transfusion reactions, and in patients with an expected protracted platelet requirement. CMV antibody negative products are recommended for all immuno-deficient patients and pregnant women negative for CMV antibody. Irradiated blood products are used in the treatment of immuno-deficient patients receiving large amounts of blood, and in all severely immuno-compromised patients. In emergency situations where CMV antibody negative and/or irradiated blood products cannot be supplied, leucocyte filtration is suggested. PMID:2154061

  14. [Phytomass utilization and deposition of feces by ungulates on steppe pastures of eastern Mongolia].

    Science.gov (United States)

    Abaturov, B D; Dmitriev, I A; Jargalsaikhan, L; Omarov, K Z

    2008-01-01

    The amount of phytomass removed by a complex of livestock (horses, cattle, sheep, and goats) and wild ungulates (Mongolian gazelle Procapra gutturosa Pall.) grazing in plain and mountain pastures of eastern Mongolia has been estimated by taking account of feces deposited by these animals. The results show that at an animal density of up to 30 head/km2, the total annual amount of feces reaches 140 kg/ha (dry weight), with the greater part (up to 90 kg/ha) being deposited by horses. The contribution of Mongolian gazelles in some pastures reaches 20-40 kg/ha per year. Decomposition of feces proceeds very slowly, with the annual loss of their weight averaging only 9-12%. This is evidence for gradual accumulation of nondecomposed matter in the soil. The removal of phytomass by the complex of ungulates, calculated from the amount of feces with regard to their annual loss and forage digestibility, varies in different grazing areas from 240 to 400 kg/ha (25-60% of the total aboveground phytomass). The greatest amount of phytomass is utilized by horses, reaching 200 kg/ha (13%), and Mongolian gazelles utilize up to 86 kg/ha per year. In the growing season, ungulates remove no more than 11-16% of the total aboveground phytomass. It is concluded that the impact of total ungulate stock does not impair the productivity of vegetation in the pastures studied. PMID:18663973

  15. Efficacy of Rodent Control in Alfalfa and Wheat Crops Using Chemical and Natural Rodenticides

    Directory of Open Access Journals (Sweden)

    Suzana Đedović

    2007-01-01

    Full Text Available Biological efficacy of chemical and natural rodenticides in controlling rodents in alfalfa and wheat crops was investigated. The experiment was set up using a randomized block design with four replicates and 400 m2 plots in compliace with a standard OEPP/EPPO method. Examination was based on the average number of active holes and rodenticide efficacy was measured three, seven, 14 and 28 days after treatment. Rodent numbers were computed from the number of active holes, and rodenticide efficacy using Abbott’s formula.The appearance and arrangement of active holes indicated the presence of common vole (Microtus arvalis Pall and striped field mouse (Apodemus agrarius in the plots. The products tested demonstrated satisfactory efficacy in controlling rodents in alfalfa and wheatcrops. Products based on vitamin D3 achieved 87-90% efficacy in both crops. The efficacy of a bromadiolone-based product ranged from 84% to 90%, while a cellulose product displayed the highest variation in efficacy, ranging from 86% to 98%.

  16. Analysis of flavonoids by capillary zone electrophoresis with electrokinetic supercharging.

    Science.gov (United States)

    Zhong, Hao; Yao, Qingqiang; Breadmore, Michael C; Li, Yumei; Lu, Yuanqi

    2011-11-01

    On-line concentration via Electrokinetic Supercharging (EKS) was used to enhance the sensitivity of the capillary electrophoretic separation of the four flavonoids naringenin, hesperetin, naringin and hesperidin. Separation conditions, including the background electrolyte pH and concentration, the length and choice of terminator and the electrokinetic injection time were optimized. The optimum conditions were: a background electrolyte of 30 mM sodium tetraborate (pH 9.5) containing 5% (v/v) of methanol, electrokinetic injection of the sample (130 s, -10 kV) followed by hydrodynamic injecting of 100 mM 2-(cyclohexylamino)ethanesulfonic acid (CHES) (17 s, 0.5 psi) as terminator, and separation with -20 kV. Under these conditions the four flavonoids could be separated with a sample-to-sample time of 15 min and detection limits from 2.0 to 6.8 ng mL(-1). When compared to a conventional hydrodynamic injection the sensitivity was enhanced between 824 and 1515 times which is 7.6-16 times higher than other CE methods for the on-line concentration of flavonoids. The applicability of the developed method was demonstrated by the detection of the four flavonoids in an aqueous extract of Clematis hexapetala pall. PMID:21949941

  17. [Flower species identification and coverage estimation based on hyperspectral remote sensing data in Hulunbeier grassland].

    Science.gov (United States)

    Gai, Ying-Ying; Fan, Wen-Jie; Xu, Xi-Ru; Yan, Bin-Yan; Wang, Huan-Jiong; Liu, Yuan

    2011-10-01

    Monitoring grassland species and area real-timely and accurately is of great significance in species diversity research, as well as in sustainable development of ecosystem. Flowers have their own unique spectral characteristics. Compared with the nutrient stage, species are more easily identified by florescence. So, florescence is a critical period for identification. In the present paper, spectral differences among such flowers as Galium verum Linn., Hemerocallis citrina Baroni, Serratula centauroides Linn., Clematis hexapetala Pall., Lilium concolor var. pulchellum, Lilium pumilum and Artemisia frigida Willd. Sp. Pl. were found, along with identification methods, by analyzing canopies spectra and parametrizing characteristics. Verification results showed that when the coverage of flowers was greater than 10%, the accuracy of identification methods would be higher than 90%. On this basis, linear unmixing model was adopted to calculate the area of flowers in quadrates. Results showed that linear unmixing model was an effective method for estimating the coverage of flowers in grassland because the accuracy was about 4%. PMID:22250555

  18. Transradial arterial chemoembolization reduces complications and costs in patients with hepatocellular carcinoma

    Directory of Open Access Journals (Sweden)

    T Wu

    2015-01-01

    Full Text Available Purpose: To improve patient comfort and reduce complications, clinical benefit of a transradial approach for transcatheter arterial chemoembolization (TACE was evaluated in patients with hepatocellular carcinoma (HCC. Methods: A total of 284 patients with HCC for TACE was divided into transradial approach group (n = 126 and transfemoral approach group (n = 158. These two groups of cases were retrospectively compared with regard to complications, the procedural time, X-ray exposure time, length of hospitalization, and hospital costs. Results: There were lower incidence rates of complications including abdominal distension (42.85% vs. 87.97%, P> 0.001, vomiting (53.17% vs. 77.22%, P < 0.001, lumbago (1.59% vs. 97.46%, P < 0.001, and dysuria (0% vs. 62.03%, P < 0.001 in the transradial group as compared with the transfemoral group. The time required for catheterization and total X-ray exposure time were less in the transradial group compared with the transfemoral group (Pall < 0.001. The hospital stay time and costs required for catheterization were less in the transradial group compared with the transfemoral group (P < 0.001 and P = 0.001, respectively. In addition, hepatic angiography and TACE were completed in 100% and 99.2% cases in transfemoral and transradial groups, respectively. Conclusions: Transradial approach for TACE improves quality of life in patients with HCC by offering fewer complications and lower costs compared with transfemoral approach.

  19. Molecular characterization of RsMPK2, a C1 subgroup mitogen-activated protein kinase in the desert plant Reaumuria soongorica.

    Science.gov (United States)

    Liu, Yubing; Li, Xinrong; Tan, Huijuan; Liu, Meiling; Zhao, Xin; Wang, Jin

    2010-01-01

    Reaumuria soongorica (Pall.) Maxim. is a short woody shrub widely found in semi-arid areas of China, and can survive severe environmental stresses. To understand its potential signaling transduction pathway in stress tolerance, we investigated the participation of mitogen-activated protein kinases (MAPKs) as possible mediators of abiotic stresses. A novel MAP kinase cDNA (RsMPK2) that encodes a 374 amino acid protein was isolated from R. soongorica. RsMPK2 belongs to the C1 subgroup, which is still functionally uncharacterized compared to groups A and B; and contains all 11 of the conserved MAPK subdomains and the TEY phosphorylation motif. RsMPK2 is expressed in vegetative (root, stem, leaf and callus) and reproductive (flower) organs. The transcripts of RsMPK2 were rapidly accumulated at high levels when R. soongorica was subjected to dehydration, salinity conditions and treatment with abscisic acid or hydrogen peroxide. Growth analysis of Escherichia coli (srl::Tn10) cells transformed with pPROEXHT-RsMPK2 showed that the expression products of RsMPK2 do not act as an osmoprotectant. But, the inhibition of RsMPK2 expression by the inhibitor U0126 induced a decrease of antioxidant enzyme activity under stresses, indicating that RsMPK2 is involved in the regulation of the antioxidant defense system in the response to stress signaling. PMID:20833058

  20. Diversity of arbuscular mycorrhizal fungi associated with desert ephemerals growing under and beyond the canopies of Tamarisk shrubs

    Institute of Scientific and Technical Information of China (English)

    SHI Zhaoyong; ZHANG Liyun; FENG Gu; Christie Peter; TIAN Changyan; LI Xiaolin

    2006-01-01

    The arbuscular mycorrhizal (AM) fungal status of the four most common ephemeral plant species, Chorispora tenella (Pall.) DC., Ceratocephalus testiculatus (Crantz) Bess., Eremopyrum orientale (L.) Jaub et. Spash and Veronica campylopoda Boiss growing in an area dominated by Tamarisk shrubs (Tamarix spp.) was investigated.Samples of the four ephemerals and their rhizosphere soils were collected from underneath and beyond the canopies of the Tamarisk shrubs.Plant mycorrhizal status and soil AM fungal spore densities and community structures were analyzed and compared under and beyond the shrub canopies.The mycorrhizal colonization rates of the ephemerals and spore densities in their corresponding rhizosphere soils were significantly lower under the shrub canopies than beyond. The number of AM fungal species under the shrubs (12) was also lower than beyond the canopies (19). When soil properties in the rhizospheres of the four ephemerals were examined, available N and P and total P, organic matter content, total salt content and electrical conductivity (EC) were all higher under the canopies than beyond. In contrast, soil available K and pH showed no such trend. A total of 21 AM fungal species were isolated from rhizosphere soils of the four ephemerals. Five belonged to Acaulospora, one to Archaeospora, thirteen to Glomus and two to Paraglomus. We conclude that the canopies of Tamarix spp. exerted some influence on the AM status of the ephemerals and on the AM fungal communities and some of the properties of their rhizosphere soils.

  1. Some Physiological Responses of Chinese Iris to Salt Stress

    Institute of Scientific and Technical Information of China (English)

    BAI Wen-Bo; LI Pin-Fang; LI Bao-Guo; H. FUJIYAMA; FAN Fen-Cheng

    2008-01-01

    Chinese iris (Iris lactea Pall. Var. Chinensis (Fisch) Koidz.), a robust iridaceous plant, is widesprcad in arid and semiarid regions with high salinity. However, the mechanism of its salt tolerance is not well understood. In this study,plant growth, water status, content and distribution of inorganic ions, cell membrane permeability, and proline content of I. Lactea under salt stress were investigated using nutrient solutions with six NaCl concentrations ranging from 0 to 350 mmol L-1. The results indicated that the biomass, height, fresh weight, K+ content, and K+/Na+ and Ca2+/Na+ratios decreased with increasing NaCl stress, whereas plant water deficit and contents of Na+ and Cl- increased with increasing NaCl stress. In all salt treatments, water deficit of shoots was found to be higher than that of roots and had a positive correlation with salt concentration. When the NaCl concentration was less than 280 mmol L-1, the ion absorption selectivity ratio and the transportation selectivity ratio sharply increased with increasing NaCl stress. Under medium salt stress, I. Lactea exhibited a strong K+ selective absorption and the transportation of K+ from roots to shoots increased, whereas Na+ was not transported and was mostly retained in roots. The plants were able to maintain osmotic adjustment through the accumulation of Na+, Cl-, and proline. On the basis of its biomass production under salt stress,I. Lactea could be considered as a facultative halophyte.

  2. Application of a cholinesterase biosensor to screen for organophosphorus pesticides extracted from soil.

    Science.gov (United States)

    Kumaran, S; Morita, M

    1995-04-01

    Based on the principle of enzyme inactivation, a butyrylcholinesterase (EC 3.1.1.8.) biosensor, to determine some organophosphorus (ORP) pesticides (Fenitrothion, Diazinon, Parathion ethyl, Mevinphos and Heptenophos) in soil extracts, is presented. The enzyme was immobilized on pre-activated Pall Biodyne(TM) transfer membranes, which were physically attached to the sensitive ends of glass pH electrodes. Contact of the enzyme with pesticide samples results in specific inhibition of enzyme activity. Sensor calibration was possible by correlating the inhibition of enzyme activity (monitored by observing reduction in electrode potential changes with substrate additions) with varying concentrations of pesticide compounds in a buffer solution. A simple procedure was designed to extract ORP pesticides from spiked soil samples using a mixture of dichloromethane and acetone as the extraction solvent mixture. The sensor was successfully used to determine pesticide concentrations ranging from a low of 35 ppb (Diazinon) to 21 ppm (Fenitrothion) in soil, with resultant relative standard deviations of percentage enzyme inactivation less than 12%. The complete extraction and analytical procedure is simple, inexpensive and rapid. Mass production of the enzyme membranes and their easy attachment to the electrodes, render them disposable after a single use. The biosensor is seen as a potential analytical instrument for early warning against pesticide contaminations in soil. PMID:18966276

  3. Integrating sand control, completion decisions pay off

    Energy Technology Data Exchange (ETDEWEB)

    Renfro, K.D.; Procyk, A.

    1998-10-01

    Anadarko recently completed an open-hole, horizontal gas well in the Gulf of Mexico using completion and sand control techniques that have proven extremely successful, judging from the production numbers. The well, in the East Addition, High Island Area, about 120 miles southeast of Galveston in 341-ft waters, was completed with a Pall Stratapac Sand Control Screen without a gravel pack. The flow rate of the well is four to sic times what would have been expected from a conventional, vertical, gravel-packed well with similar conditions. The well`s peak production rate was 22.0 MMcfd, and the well produced a total of more than 2.635 bcf of gas from November 1997 to July 1998. Drawdown was calculated at less than 40 psi, and a skin factor of negative 3.5 indicates that formation damage during the completion was negligible. The full range of completion and sand control decisions came together to make this well a success.

  4. Evaluation of Alternative Filter Media for the Rotary Microfilter

    Energy Technology Data Exchange (ETDEWEB)

    Poirier, M. R.; Herman, D. T.; Bhave, R.

    2011-11-09

    The Savannah River Site is currently developing and testing several processes to treat high level radioactive liquid waste. Each of these processes has a solid-liquid separation process that limits its throughput. Savannah River National Laboratory researchers identified and tested the rotary microfilter as a technology to increase solid-liquid separation throughput. The authors believe the rotary microfilter throughput can be improved by using a better filter membrane. Previous testing showed that asymmetric filters composed of a ceramic membrane on top of a stainless steel support produced higher filter flux than 100% stainless steel symmetric filters in crossflow filter tests. Savannah River National Laboratory and Oak Ridge National Laboratory are working together to develop asymmetric ceramic ? stainless steel composite filters and asymmetric 100% stainless steel filters to improve the throughput of the rotary microfilter. The Oak Ridge National Laboratory Inorganic Membrane Group fabricated samples of alternative filter membranes. In addition, Savannah River National Laboratory obtained samples of filter membranes from Pall, Porvair, and SpinTek. They tested these samples in a static test cell with feed slurries containing monosodium titanate and simulated sludge.

  5. Structural characterisation of the polysaccharides from endemic Mongolian desert plants and their effect on the intestinal absorption of ovalbumin.

    Science.gov (United States)

    Golovchenko, Victoria V; Khramova, Daria S; Shashkov, Alexandre S; Otgonbayar, Dorjgoo; Chimidsogzol, Aria; Ovodov, Yury S

    2012-07-15

    Using successive extractions with water and 0.7% aqueous ammonium oxalate, pectic polysaccharides were isolated from the following plants growing in the arid climate of Mongolia (Gobi): saxaul Haloxylon ammodendron Maxim., rhubarb Rheum nanum Sievers, Nitraria sibirica Pall., Peganum harmala L. and almond Amygdalus mongolica Maxim. The data obtained exhibited the primary synthesis of the cell wall pectic polysaccharides but not the middle lamellae water-soluble pectins in plants growing in the dry climatic zone. Both α-(1→4)-D-galacturonan and α-(1→4)-D-galacturonan, which was substituted with methyl groups, were found to be backbone of pectins. The L-arabinofuranose residues were identified as the main components of ramified regions. The pectins from almond differed from other pectins due to a high arabinose content. The data from NMR spectroscopy and methylation analyses demonstrated that pectic polysaccharides from almond included terminal, (1→5)-, (1→3)-linked and 3,5-substituted L-arabinofuranose residues and a small terminal D-galactopyranose and 2,5- and 2,3,5-substituted L-arabinofuranose residue content. The pectic polysaccharides were found to decrease the absorption of ovalbumin (OVA) in the blood from the gut lumen. The serum OVA level was lower in mice fed with OVA mixed with the pectins compared with the control group, which was administered OVA alone. PMID:22549013

  6. Effects of Salinity on growth and osmotic regulation substances of callus induced from Reaumuria soongorica

    Science.gov (United States)

    Tan, Huijuan; Li, Xinrong; Liu, Yubing; Zhao, Xin

    2014-05-01

    Reaumuria soongorica (Pall.) Maxim is the strong xerophils plant in the northwest arid and semiarid regions in China. It plays very important roles in stabilizing sand dunes and in construction of agricultural shelter belts in north-west China.The present study aimed to evaluate the response to salinity of R. soongorica, which is more salt-resistant than other valuable shrub species used for afforestation on saline and alkaline desert, at the cellular level. To this purpose, callus was induced from shoot segments of R. soongorica on Murashige and Skoog (MS) medium supplemented with 0.2 mgL-16-benzyladenine (BA) and 2.0 mg mgL-1 2,4-Dichlorophenoxyacetic acid (2 ,4-D). The relative growth rate of callus reached a maximum in the presence of 100 mmol L-1NaCl and growth was inhibited with increasing NaCl concentrations. Examination of the changes of osmotic substances under salt stress showed that accumulation of proline, trehalose, Glycine betain and flavonoids increased with increasing salt concentrations. The results indicate that the response of the callus of R. soongorica to salt stress is similar to that of the whole plant. .

  7. Virosecurinine induces apoptosis by affecting Bcl-2 and Bax expression in human colon cancer SW480 cells.

    Science.gov (United States)

    Chen, Chuan-Rong; Xia, Yong-Hui; Yao, Shu-Yan; Zhang, Qing; Wang, Ying; Ji, Zhao-Ning

    2012-04-01

    Virosecurinine, the major alkaloid isolated from Securinega suffruticosa Pall Rehd was found to exhibit growth inhibition and cytotoxicity against huaman colon cancer SW480 cells via the microculture tetrazolium (MTT) assay. Due to its greater cytotoxic potency and selectivity towards SW480 cells, flow cytometry was used to analyze the cell cycle distribution of control and treated SW480 cells whereas Annexin V-FITC/PI flow cytometry analysis was carried out to confirm apoptosis induced by virosecurinine in SW480 cells. Apoptotic regulatory genes were determined by RT-PCR analysis. Virosecurinine was found to induce G1/S cell cycle arrest which led to predominantly apoptotic mode of cell death. Mechanistically, virosecurinine was found to up-regulated the Bax gene expression and down-regulated the Bcl-2 expression in SW480, The ratio of Bcl-2 to Bax was significantly decreased. Hence, we suggest that virosecurinine induced apoptosis in SW480 cells by affecting the expression of bcl-2 and bax. PMID:22570942

  8. Harvest season, high polluted season in East China

    International Nuclear Information System (INIS)

    East China, a major agricultural zone with a dense population, suffers from severe air pollution during June, the agricultural harvest season, every year. Crop burning emits tremendous amounts of combustion products into the atmosphere, not only rapidly degrading the local air quality but also affecting the tropospheric chemistry, threatening public health and affecting climate change. Recently, in mid-June 2012, crop fires left a thick pall of haze over East China. We evaluated the PM10, PM2.5 (particulates less than 10 and 2.5 μm in aerodynamic diameter) and BC (black carbon) emissions by analyzing detailed census data and moderate resolution imaging spectroradiometer (MODIS) remote sensing images and then simulated the consequent pollution using meteorological and dispersion models. The results show that the crop fires sweeping from the south to the north are responsible for the intensive air pollution during harvest season. It is necessary for scientists and governments to pay more attention to this issue. (letter)

  9. Styrene biofiltration in a trickle-bed reactor

    Directory of Open Access Journals (Sweden)

    V. Novak

    2008-04-01

    Full Text Available The biological treatment of styrene waste gas in a trickle-bed filter (TBF was investigated. The bioreactor consisted of a two-part glass cylinder (ID 150 mm filled with 25 mm polypropylene Pall rings serving as packing material. The bed height was 1m. Although the laboratory temperature was maintained at 22 ºC, the water temperature in the trickle-bed filter was slightly lower (about 18 ºC.The main aim of our study was to observe the effect of empty-bed residence time (EBRT on bioreactor performance at a constant pollutant concentration over an extended time period. The bioreactor was inoculated with a mixed microbial consortium isolated from a styrene-degrading biofilter that had been running for the previous two years. After three weeks of acclimation period, the bioreactor was loaded with styrene (100 mg.m-3. EBRT was in the range of 53 s to 13 s. A maximum elimination capacity (EC of 11.3 gC.m-3.h-1 was reached at an organic loading (OL rate of 18.6 gC.m-3.h-1.

  10. Depressão e qualidade de vida em pacientes com fibromialgia Depression and quality of life among patients with fibromyalgia

    Directory of Open Access Journals (Sweden)

    AMB Santos

    2006-09-01

    Full Text Available CONTEXTO: Fibromialgia é uma síndrome reumática caracterizada por dor musculoesquelética difusa e crônica, e sítios dolorosos específicos à palpação (tender points. Freqüentemente é associada à fadiga generalizada, distúrbios do sono, rigidez matinal, dispnéia, ansiedade, alterações no humor que podem evoluir para um quadro de depressão. Sendo assim, afeta negativamente a qualidade de vida das pessoas. No entanto, ainda não se sabe o poder de discriminação dos instrumentos de avaliação da depressão e qualidade de vida. O objetivo desse estudo foi avaliar a depressão e a qualidade de vida de pacientes com fibromialgia e avaliar o poder de discriminação de instrumentos relacionados a esses aspectos. MÉTODO: Para avaliar a qualidade de vida foram utilizados dois instrumentos: um específico, o Fibromyalgia Impact Questionnaire (FIQ e outro genérico, o Medical Outcomes Study 36-item Short-Form Healthy Survey (SF-36; para avaliar a depressão, a Escala de Depressão de Beck (BDS. Participaram do estudo 40 mulheres sendo 20 com fibromialgia - Grupo teste e 20 saudáveis - Grupo controle. Os três protocolos foram aplicados aos indivíduos dos dois grupos em uma única sessão de avaliação. Toda a análise estatística foi realizada utilizando-se o teste "t" Student, com significância alfa = 0,05. RESULTADOS: Houve diferença estatisticamente significante entre os grupos controle e teste em todos os questionários (pBACKGROUND: Fibromyalgia is a rheumatic syndrome characterized by widespread chronic musculoskeletal pain and specific palpable tender points. It is often associated with generalized fatigue, sleep disturbances, morning stiffness, dyspnea, anxiety and mood disturbances that may evolve into depression. Thus, such individuals' quality of life is negatively affected. However, the discriminating power of quality-of-life and depression assessment instruments is still unknown. OBJECTIVE: To assess depression and

  11. Determination of longistylin A and longistylin C in Cajanus cajan%树豆菧类化合物longistylin A和longistylin C的检测

    Institute of Scientific and Technical Information of China (English)

    王达武; 肖敏勋; 李宜融; 沈小玲; 卢元媛; 刘抗伦; 李正红; 胡英杰

    2011-01-01

    Objective: To establish quality control criteria for medicinal herb Cajanus cajan based on the determination of longistylin A and longistylin C, two bioactive and specific stilbenes of the plant Method: Longistylin A and longistylin C were obtained from the leaves of C. cajan by silica gel column chromatography and identified as marker compounds of this plant by spectroscop-ic analysis. A RP-HPLC method was established to determine the two compounds. Result; Longistylin A and longistylin C were well separated on a Thermo BDS Hypersil C18 column (4. 6 mm x250 mm, S μm) with a mobile phase methanol-water (8:2) , and showed good linearity in the range of 0. 002 88-0.057 6 μg and 0. 011 2-0. 224 μg, respectively. The average recoveries were 98. 9% and 97. 2% with RSD of 2.4% and 2. 2% for these two compounds, respectively. Conclusion: The established analysis method is simple and accurate, whicn can be used for quality control of C. cajan.%目的:建立以药物活性和专属性菧类成分longistylin A与longistylin C为评价指标的树豆(木豆)药材质量控制方法.方法:采用硅胶柱色谱分离纯化有关成分,光谱技术鉴定化学结构;反相高效液相色谱法测定指标成分的含量.结果:从树豆叶分离鉴定了2种指标成分longistylin A和longistylin C;采用Thermo BDS Hypersil C18色谱柱(4.6 mm×250 mm,5μm),以甲醇-水(80:20)为流动相可使指标成分获得良好分离;longistylin A和longistylin C分别在0.002 88~0.057 6μg和0.011 2~0.224 μg呈良好的线性关系,平均回收率分别为98.9%,97.2%,RSD分别为2.4%,2.2%.结论:建立了以树豆叶中药物活性菧类成分为指标的药物分析方法,可用于树豆(木豆)药材的质量控制.

  12. Phenology of forest-grassland transition zones in the Community Land Model

    Science.gov (United States)

    Dahlin, K.; Fisher, R. A.

    2013-12-01

    Forest-grassland transition zones (savannas, woodlands, wooded grasslands, and shrublands) are highly sensitive to climate and may already be changing due to warming, changes in precipitation patterns, and/or CO2 fertilization. Shifts between closed canopy forest and open grassland, as well as shifts in phenology, could have large impacts on the global carbon cycle, water balance, albedo, and on the humans and other animals that depend on these regions. From an earth system perspective these impacts may then feed back into the climate system and impact how, when, and where climate change occurs. Here we compare 29 years of monthly leaf area index (LAI) outputs from several offline versions of the Community Land Model (CLM), the land component of the Community Earth System Model, to LAI derived from the AVHRR NDVI3g product (LAI3g). Specifically, we focus on seasonal patterns in regions dominated by tropical broadleaved deciduous trees (T-BDT), broadleaved deciduous shrubs (BDS) and grasslands (C3 and C4) in CLM, all of which follow a 'stress deciduous' phenological algorithm. We consider and compare two versions of CLM (v. 4CN and v. 4.5BGC) to the satellite derived product. We found that both versions of CLM were able to capture seasonal variations in grasslands relatively well at the regional scale, but that the 'stress deciduous' phenology algorithm did not perform well in areas dominated by T-BDT or BDS. When we compared the performance of the models at single points we found slight improvements in CLM4.5BGC over CLM4CN, but generally that the magnitude of seasonality was too low in CLM as compared to the LAI3g satellite product. To explore the parameters within CLM that had the most leverage on seasonality of LAI, we used a Latin hypercube approach to vary values for critical soil water potential (threshold at which plants drop leaves), the critical number of days that soil water potential must be too low for leaves to drop, and the carbon allocation scheme

  13. 分子印迹固相萃取-液相色谱法测定喘息灵胶囊中盐酸克仑特罗的含量%Determination of clenbuterol hydrochloride with molecularly imprinted solid phase extraction- high performance liquid chromatography in Chuangxiling capsules

    Institute of Scientific and Technical Information of China (English)

    黄红萍; 游勇基

    2012-01-01

    目的:建立分子印迹固相萃取-高效液相色谱法测定喘息灵中盐酸克仑特罗含量.方法:采用Hypersil BDS C18 (250mm×4.6 mm,5μm)色谱柱,以0.05 moL·L-1NaH2P04(含0.005 moL·L-1PIC - B6,用磷酸调pH至4.0左右)和甲醇(60∶40)为流动相,检测波长为245 nm,流速为1.0 mL·min-1;柱温为室温.结果:盐酸克仑特罗浓度在0.4~40.0 μg·mL-1范围内呈良好线性关系(r =0.9998),盐酸克仑特罗的平均回收率为97.8%,(RSD为0.9%,n=9).结论:方法简便,分离效果好,结果准确可靠.%Objective: To establish a method for determination of clenbuterol hydrochloride in Chuanxiling with mo-lecularly imprinted solid phase extraction -high performance liquid chromatography. Methods: The analysis was carried on a Hypersil BDS C18(250 mm ×4. 6 mm,5 μm) column;The mobile phase was composed of 0. 05 moL·L-1 NaH2PO4(containing 0. 005 moL·L-1 PIC - B6,adjust the pH to 4. 0 with phosphoric acid) and methanol (60:40) ;the detection wavelength was 245 nm and the flow rate was 1. 0 mL·min-1; column temperature was at room temperature. Results: The linear range was 0. 4 - 40. 0μg·mL-1' (r = 0. 9998 ) for clenbuterol hydrochloride, the average recovery of clenbuterol hydrochloride was 97. 8% (RSD = 0. 9% , n - 9). Conclusion: This method is simple,rapid and accurate.

  14. Calorimetric and relaxation properties of xylitol-water mixtures

    Science.gov (United States)

    Elamin, Khalid; Sjöström, Johan; Jansson, Helén; Swenson, Jan

    2012-03-01

    We present the first broadband dielectric spectroscopy (BDS) and differential scanning calorimetry study of supercooled xylitol-water mixtures in the whole concentration range and in wide frequency (10-2-106 Hz) and temperature (120-365 K) ranges. The calorimetric glass transition, Tg, decreases from 247 K for pure xylitol to about 181 K at a water concentration of approximately 37 wt. %. At water concentrations in the range 29-35 wt. % a plentiful calorimetric behaviour is observed. In addition to the glass transition, almost simultaneous crystallization and melting events occurring around 230-240 K. At higher water concentrations ice is formed during cooling and the glass transition temperature increases to a steady value of about 200 K for all higher water concentrations. This Tg corresponds to an unfrozen xylitol-water solution containing 20 wt. % water. In addition to the true glass transition we also observed a glass transition-like feature at 220 K for all the ice containing samples. However, this feature is more likely due to ice dissolution [A. Inaba and O. Andersson, Thermochim. Acta, 461, 44 (2007)]. In the case of the BDS measurements the presence of water clearly has an effect on both the cooperative α-relaxation and the secondary β-relaxation. The α-relaxation shows a non-Arrhenius temperature dependence and becomes faster with increasing concentration of water. The fragility of the solutions, determined by the temperature dependence of the α-relaxation close to the dynamic glass transition, decreases with increasing water content up to about 26 wt. % water, where ice starts to form. This decrease in fragility with increasing water content is most likely caused by the increasing density of hydrogen bonds, forming a network-like structure in the deeply supercooled regime. The intensity of the secondary β-relaxation of xylitol decreases noticeably already at a water content of 2 wt. %, and at a water content above 5 wt. % it has been replaced by a

  15. Identification of a cell-penetrating peptide domain from human beta-defensin 3 and characterization of its anti-inflammatory activity

    Directory of Open Access Journals (Sweden)

    Lee JY

    2015-08-01

    Full Text Available Jue Yeon Lee,1,* Jin Sook Suh,2,* Jung Min Kim,1 Jeong Hwa Kim,1 Hyun Jung Park,1 Yoon Jeong Park,1,2 Chong Pyoung Chung1 1Central Research Institute, Nano Intelligent Biomedical Engineering Corporation (NIBEC, Chungcheongbuk-do, Republic of Korea; 2Dental Regenerative Biotechnology, Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea *These authors contributed equally to this work Abstract: Human beta-defensins (hBDs are crucial factors of intrinsic immunity that function in the immunologic response to a variety of invading enveloped viruses, bacteria, and fungi. hBDs can cause membrane depolarization and cell lysis due to their highly cationic nature. These molecules participate in antimicrobial defenses and the control of adaptive and innate immunity in every mammalian species and are produced by various cell types. The C-terminal 15-mer peptide within hBD3, designated as hBD3-3, was selected for study due to its cell- and skin-penetrating activity, which can induce anti-inflammatory activity in lipopolysaccharide-treated RAW 264.7 macrophages. hBD3-3 penetrated both the outer membrane of the cells and mouse skin within a short treatment period. Two other peptide fragments showed poorer penetration activity compared to hBD3-3. hBD3-3 inhibited the lipopolysaccharide-induced production of inducible nitric oxide synthase, nitric oxide, and secretory cytokines, such as interleukin-6 and tumor necrosis factor in a concentration-dependent manner. Moreover, hBD3-3 reduced the interstitial infiltration of polymorphonuclear leukocytes in a lung inflammation model. Further investigation also revealed that hBD3-3 downregulated nuclear factor kappa B-dependent inflammation by directly suppressing the degradation of phosphorylated-IκBα and by downregulating active nuclear factor kappa B p65. Our findings indicate that hBD3-3 may be conjugated with drugs of interest to ensure their proper translocation to

  16. 富马酸替诺福韦双特戊酯有关物质的鉴定%Identification of the related substances in tenofovir dipivoxil fumarate with hyphenated techniques

    Institute of Scientific and Technical Information of China (English)

    赵画; 宋敏; 杭太俊

    2012-01-01

    目的:采用色谱-质谱联用技术对富马酸替诺福韦双特戊酯中有关物质进行结构鉴定.方法:采用BDS Hypersil C18(250 mm×4.6 mm,5μm)色谱柱,流动相为乙腈-0.2%醋酸铵溶液,梯度洗脱,对富马酸替诺福韦双特戊酯有关物质进行分离;LC-PDA测定各有关物质的UV吸收,甲醇辅助电喷雾正离子化LC-TOF和LC-MS/MS分别测定各有关物质的精密质量和二级质谱.结果:检测到富马酸替诺福韦双特戊酯中存在多个有关物质,其中仅3个的含量在0.1%以上,并鉴定出4个主要有关物质的结构.结论:色谱-质谱联用技术能够有效地鉴定药物中的有关物质,富马酸替诺福韦双特戊酯有关物质鉴定结果对其质量控制和工艺优化提供了参考依据.%Objective:To identify the related substances in tenofovir dipivoxil fumarate by hyphenated techniques. Methods: An LC-PDA-MS/MS method was established by using acetonitrile-O. 2% ammonium acetate as the mobile phase with gradient elution on a BDS Hypersil C18 (250 mm × 4. 6 mm,5 μm) column with 0. 2 mL-min methanol aided electro-spray positive ionization. The UV spectrum, accurate molecular weight and formula, and product ion MS spectrum of each related substance was obtained by LC-PDA ,LC-TOF and LC-MS/MS,respectively. Results: Several related substances were found in tenofovir dipivoxil fumarate with only 3 of them had the area normalization content over 0. 1% , and 4 of them were identified and elucidated. Conclusion: The hyphenated LC-MS method is useful for the determination and identification of related substances in pharmaceuticals. Identification of the related compounds in tenofovir dipivoxil fumarate is valuable for its manufacturing process optimization and quality control.

  17. Measurements of fast neutrons by bubble detectors

    Energy Technology Data Exchange (ETDEWEB)

    Castillo, F.; Martinez, H. [Laboratorio de Espectroscopia, Instituto de Ciencias Fisicas, Universidad Nacional Autonoma de Mexico, Apartado Postal 48-3, 62251, Cuernavaca Morelos (Mexico); Leal, B. [Instituto de Ciencias Nucleares, Universidad Nacional Autonoma de Mexico, Apartado Postal 70-543, 04510, Ciudad Universitaria, Mexico D. F. (Mexico); Rangel, J. [Instituto de Ciencias Nucleares, Universidad Nacional Autonoma de Mexico, Apartado Postal 70-543, 04510, Ciudad Universitaria, Mexico D. F (Mexico); Reyes, P. G. [Facultad de Ciencias, Universidad Autonoma del Estado de Mexico, Instituto Literario 100, Col. Centro, 50000, Toluca Estado de Mexico (Mexico)

    2013-07-03

    Neutron bubble detectors have been studied using Am-Be and D-D neuron sources, which give limited energy information. The Bubble Detector Spectrometer (BDS) have six different energy thresholds ranging from 10 KeV to 10 Mev. The number of bubbles obtained in each measurement is related to the dose (standardized response R) equivalent neutrons through sensitivity (b / {mu}Sv) and also with the neutron flux (neutrons per unit area) through a relationship that provided by the manufacturer. Bubble detectors were used with six different answers (0.11 b/ {mu}Sv, 0093 b/{mu}Sv, 0.14 b/{mu}Sv, 0.17 b/{mu}Sv, 0051 b/{mu}Sv). To test the response of the detectors (BDS) radiate a set of six of them with different energy threshold, with a source of Am-Be, placing them at a distance of one meter from it for a few minutes. Also, exposed to dense plasma focus Fuego Nuevo II (FN-II FPD) of ICN-UNAM, apparatus which produces fusion plasma, generating neutrons by nuclear reactions of neutrons whose energy emitting is 2.45 MeV. In this case the detectors were placed at a distance of 50 cm from the pinch at 90 Degree-Sign this was done for a certain number of shots. In both cases, the standard response is reported (Dose in {mu}Sv) for each of the six detectors representing an energy range, this response is given by the expression R{sub i}= B{sub i} / S{sub i} where B{sub i} is the number of bubbles formed in each and the detector sensitivity (S{sub i}) is given for each detector in (b / {mu}Sv). Also, reported for both cases, the detected neutron flux (n cm{sup -2}), by a given ratio and the response involves both standardized R, as the average cross section sigma. The results obtained have been compared with the spectrum of Am-Be source. From these measurements it can be concluded that with a combination of bubble detectors, with different responses is possible to measure the equivalent dose in a range of 10 to 100 {mu}Sv fields mixed neutron and gamma, and pulsed generated fusion

  18. SPE- HPLC determination of pyrethroid pesticide residues in Platycodon grandiflorum%固相萃取-高效液相色谱法测定桔梗中拟除虫菊酯的农药残留

    Institute of Scientific and Technical Information of China (English)

    翁淑琴; 游勇基

    2011-01-01

    目的:建立桔梗中甲氰菊酯、高效氯氟氰菊酯、溴氰菊酯、氰戊菊酯、氯菊酯、联苯菊酯共6个拟除虫菊酯类农药残留的提取、净化及其残留量测定的方法.方法:样品运用石油醚提取,商品CARB/NH2小柱净化,乙腈-二氯甲烷(5:95)洗脱,HPLC - DAD检测.色谱条件:采用Hypersil BDS C18(250 mm ×4.6 mm,5μm)色谱柱,流动相为乙腈-水(70:30),流速1mL·min-1,检测波长230nm.结果:样品4水平添加时的6个拟除虫菊酯类化合物回收率在75.63%~107.5%范围内,RSD在2.3% ~9.9%范围内,可以满足农药残留分析的要求.结论:该方法灵敏度高,选择性强,操作简单、快速,净化效果好.可应用于桔梗药材中痕量农药残留的检测.%Objective: To develop a method for the extraction, clean - up and determination of fenpropathrin, lambda - cyhalothrin, deltamethrin, fenvalerate, permethrin and bifenthrin in Platycodon grandiflorum. Methods: Pesticide residues were extracted from samples with ligarine; Extracts were cleaned - up by CARB/NH2 column, eluted with acetonitrile -chloromethane(5: 95). Analytical screening was determined by HPLC with a diode array detector. HPLC condition:Hypersil BDS C18(250mm ×4. 6 mm,5 μm)column was adopted,the mobile phase consisted of acetonitrile - water(70: 30) at a flow rate of 1 mL · min-1 ,and the detection wavelength was 230 ran. Results; The average recoveries were in the range of 75. 63% - 107. 6% with RSD of 2. 3% - 9. 9%. The method met the requirement of pesticide residue analysis. Conclusion: The proposed method has high sensitivity, repeatability and selectivity, it is simple and fast, which can be used for the analysis of 6 pyrethroid pesticides.

  19. Magellan adaptive optics first-light observations of the exoplanet β PIC b. I. Direct imaging in the far-red optical with MagAO+VisAO and in the near-IR with NICI {sup ,}

    Energy Technology Data Exchange (ETDEWEB)

    Males, Jared R.; Close, Laird M.; Morzinski, Katie M.; Skemer, Andrew J.; Kopon, Derek; Follette, Katherine B.; Hinz, Philip M.; Rodigas, Timothy J. [Steward Observatory, University of Arizona, Tucson, AZ 85721 (United States); Wahhaj, Zahed [European Southern Observatory, Alonso de Cordova 3107, Vitacura, Casilla 19001 Santiago (Chile); Liu, Michael C.; Nielsen, Eric L.; Chun, Mark [Institute for Astronomy, University of Hawaii, 2680 Woodlawn Drive, Honolulu, HI 96822 (United States); Puglisi, Alfio; Esposito, Simone; Riccardi, Armando; Pinna, Enrico; Xompero, Marco; Briguglio, Runa [Arcetri Observatory/INAF, Largo E. Fermi 5, I-50125-Firenze (Italy); Biller, Beth A. [Institute for Astronomy, The University of Edinburgh, Royal Observatory, Blackford Hill, Edinburgh EH9 3HJ (United Kingdom); Hayward, Thomas L., E-mail: jrmales@as.arizona.edu [Gemini Observatory, Southern Operations Center, c/o AURA, Casilla 603, La Serena (Chile); and others

    2014-05-01

    We present the first ground-based CCD (λ < 1 μm) image of an extrasolar planet. Using the Magellan Adaptive Optics system's VisAO camera, we detected the extrasolar giant planet β Pictoris b in Y-short (Y{sub S} , 0.985 μm), at a separation of 0.470 ± 0.''010 and a contrast of (1.63 ± 0.49) × 10{sup –5}. This detection has a signal-to-noise ratio of 4.1 with an empirically estimated upper limit on false alarm probability of 1.0%. We also present new photometry from the Gemini Near-Infrared Coronagraphic Imager instrument on the Gemini South telescope, in CH {sub 4S,1%} (1.58 μm), K{sub S} (2.18 μm), and K {sub cont} (2.27 μm). A thorough analysis of our photometry combined with previous measurements yields an estimated near-IR spectral type of L2.5 ± 1.5, consistent with previous estimates. We estimate log (L {sub bol}/L {sub ☉}) = –3.86 ± 0.04, which is consistent with prior estimates for β Pic b and with field early-L brown dwarfs (BDs). This yields a hot-start mass estimate of 11.9 ± 0.7 M {sub Jup} for an age of 21 ± 4 Myr, with an upper limit below the deuterium burning mass. Our L {sub bol}-based hot-start estimate for temperature is T {sub eff} = 1643 ± 32 K (not including model-dependent uncertainty). Due to the large corresponding model-derived radius of R = 1.43 ± 0.02 R {sub Jup}, this T {sub eff} is ∼250 K cooler than would be expected for a field L2.5 BD. Other young, low-gravity (large-radius), ultracool dwarfs and directly imaged EGPs also have lower effective temperatures than are implied by their spectral types. However, such objects tend to be anomalously red in the near-IR compared to field BDs. In contrast, β Pic b has near-IR colors more typical of an early-L dwarf despite its lower inferred temperature.

  20. Quantification of Arbutin from Pear Blossoms by HPLC%梨花中熊果苷的高效液相色谱分析

    Institute of Scientific and Technical Information of China (English)

    李媛; 乔进春; 张玉星; 何童森; 吕明霞; 张飞; 崔同

    2012-01-01

    采用高效液相色谱法对不同时期、不同品种的梨花中熊果苷的含量进行了分析,色谱柱为Hypersil BDS C18 (4.6 mm×250 mm,5μm),流动相为甲醇:水(6:94),加入甲酸0.05%,检测波长280 nm.结果表明:熊果苷在0.01 ~5.00 μg范围内线性关系良好(r=0.9999),平均加标回收率为97.7%.不同生长期的鸭梨梨花中熊果苷的含量一般在10 mg/g以上,尤以花芽萌动期时含量最高,达到35.7 mg/g(鲜重计).不同品种的9份梨花样品中,熊果苷含量在3.5 -10.5 mg/g之间.%The contents of arbutin in pear blossoms of different periods and different varieties were detected using the HPLC method with Hypersil BDS C18 column (4.6 mm × 250 mm,5 μm), the mobile phase methanol: water (6:94, with 0.05% formic acid), and the detection wavelength 280 nm. The results showed that the calibration curve was linear in the range of 0.01 ~5.00μg (r = 0.9999) and the average recovery was 97.7%. The content of arbutin in Yali pear blossom during the florescence was above 10 mg/g (fresh weight) in most cases,especially in blossom bud germination period,reaching a maximum of 35.7 mg/g. In the nine pear blossom samples from different varieties,the contents of arbutin were range between 3.5 mg/g to 10.5 mg/g.

  1. Assessment of anxiety and depression in adolescents with acne vulgaris related to the severity of clinical features and gender

    Directory of Open Access Journals (Sweden)

    Nermina Kurtalić

    2010-11-01

    Full Text Available Objective. To determine anxiety and depression levels in adolescents with acne vulgaris in relation to clinical severity and gender. Patients and methods. Using a sectional study, the anxiety and depression level was analyzed of 90 adolescents of both sexes, aged 16 to 21 years, who were suffering from acne vulgaris. The study was conducted between February 1st 2008 and January 31st 2009 at the Dermatovenerology department of the Cantonal Hospital “Dr. Irfan Ljubijankić”, Bihac. According to the type of efflorescence, its localization and severity of clinical features, respondents were classified in three groups: the first group consisted of adolescents with mild forms of acne, the second group had moderate forms of acne and the third had severe forms of acne. Evaluation of anxiety levels in patients with acne vulgaris was made using STAI questionnaire (Spielberger’s state and trait Anxiety Inventory that consists of 20 questions about the essential characteristics of anxiety as the condition, and the level of depression was determined using the BDS-scale (Back Depression Inventory which consists of 18 items that were used by the respondents to perform self-evaluation of depression level. Results. In the study group there were 54 (60% female respondents and 36 (40% male, mean age 17.5 years (range 15.6-20.6. Of the total number of patients with acne vulgaris, nine of them or 10% (4 female and 5 male had a mild form of acne (first group, 72 of them or 80% (46 female and 26 male a moderate form of acne (second group and 9 of them or 10 % (4 female and 5 male a severe form of acne (third group (p > 0.95. 1.1% of the respondents had an exceptionally low anxiety level, 13.3% had low level, moderate 76.8% and 8.8% had a high level. 37.8% had distinct signs of depression, the risk group consisted of 44.4%, and a normal value was found in 17.7%. The values of the STAI questionnaire expressed as median (range in the first, second and third groups

  2. Rp-HPLC法测定阿莫西林、克拉维酸钾的含量%Determination of contents of amoxicillin and clavulanate potassium by Rp-HPLC

    Institute of Scientific and Technical Information of China (English)

    袁姗

    2010-01-01

    Objective To establish content determination method of amoxicillin and clavulanate potassium. Methods The parameters of detection was as followed: HPLC column: Hypersil BDS C18 (4.6× 200 mum, 5μm); mobile phase: sodium dodecylsulfate solution - acetonitrile (92:8); flow: 1.0ml/min;chromatographic temperature: 25C; detection wavelength: 220 nm; injection volume: 10 μ 1. ResultsThe linear range of clavulanate potassium was good at 4.05 - 40.48 μ g ( r = 0.9999 ) and the average recovery was 99.7% (RSD = 2.1%); The linear range of amoxicillin was good at 1.15 - 11.53 μ g( r = 0.9999 )and the average recovery was 99.6% (RSD = 0.7%). Conclusions This method is accurate and easy to use, with better recovery and higher separation. It can be used for quality control of the related preparations.%目的 建立阿莫西林/克拉维酸钾中两种主要成分的含量测定.方法 采用液相色谱法,大连依利特Hypersil BDS C18柱(4.6×200 mm,5 μ m)为色谱柱;十二烷基硫酸钠溶液-乙腈(92∶8)为流动相;流速:1.0ml/min;柱温:25℃;检测波长:220nm;进样体积:10 μl.结果 克拉维酸在4.05~40.48μg范围内线性良好(r=0.9999),平均回收率为99.7%(RSD=2.1%);阿莫西林在1.15~11.53μg范围内线性良好(r=0.9999),平均回收率为99.6%(RSD=0.7%).结论 该方法准确度高,回收率良好,分离度较高,操作简单,可作为该制剂质量控制方法.

  3. The effect of fibromyalgia syndrome to gravidity, parity and duration of breastfeeding; A prospective study from Turkey

    Science.gov (United States)

    Tulay, Koca Tuba; Emrullah, Tanrikut; Aydin, Arslan; Ciledag, Ozdemir Filiz

    2016-01-01

    Objectives: Fibromyalgia syndrome (FS) is a chronic pain disorder usually affecting women in their fertile period of life. However, the relationship between FS and pregnancy has not been studied in depth. The effect of FS on the course of pregnancy is poorly investigated in the current literature. Here we aimed to investigate the effects of FS to menarche age, gravidity, parity and duration of breastfeeding. Methods: One hundred and eighty-seven non-pregnant females attending between March 2015-June 2015, to Malatya State Hospital Physical Medicine and Rehabilitation Outpatient Clinic, were included in this prospective study. One hundred eleven (111) of them were diagnosed with FS according to the American Rheumatology Association (ACR) 2010 criteria and were defined as group 1; group 2 comprised of seventy six (76) non-pregnant healthy volunteers. All participants were asked about their menarche age, marriage age, gravidity, parity, duration of breastfeeding by conducting a basic questionnaire survey. Patients’ body mass index (BMI) were recorded. Depression parameters were evaluated by Beck Depression Scale (BDS). Results: The average age of the patients was 39.04±9.21 (FS) and 38.47±9.65 (Control) years; first menarche age was at 13.28±1.38 (FS) and 13.59±1.54 years (Control), and marriage age was 20.1±3.62 (FS) and 20.69±3.90 years (Control), respectively. No statistically significant difference was found (p=0.598) between BMI values (FS, 27.76±4.95; Control 26.90±4.56 kg/m2). The results from both groups were similar in terms of gravidity, parity, and breastfeeding duration, with no statistically significant differences (p=0.252, 0.093, 0.075, respectively). The only significant difference was found in the depression parameter. The BDS results were statistically different between the groups, found higher in FS group (p=0.000). Conclusion: FS occurs as a result of symptoms such as mood disorder, anxiety, cognitive and sleep disorders, and also

  4. Physical Activity Level of Post-menopausal Women with Low Bone Mineral Density.

    Science.gov (United States)

    Dallanezi, Glauber; Freire, Beatriz Funayama Alvarenga; Nahás, Eliana Aguiar Petri; Nahás-Neto, Jorge; Corrente, José Eduardo; Mazeto, Gláucia Maria Ferreira da Silva

    2016-05-01

    Introduction Proper physical activity is related to the prevention and the treatment of osteoporosis. Purpose To assess the level of physical activity (PA) in post-menopausal women with low bone mineral density (BMD). Methods This cross-sectional clinical study included 123 post-menopausal women. The inclusion criteria were: age of ≥ 45 years with last menses at least 12 months prior to the initiation of the study, and bone density scan (BDS) values measured over the preceding 12 months. Women with severe osteoarthritis were excluded. Women were allocated into three groups, according to BMD measured by BDS [osteoporosis (OP; 54 women), osteopenia (35 women), and normal bone density (NBD; 35 women)], and compared for general, clinical, and anthropometric data, and for PA level. The latter was assessed using the International Physical Activity Questionnaire (IPAQ), in metabolic equivalent of task (MET) units. Participants were classified as sedentary, active or very active. Quantitative variables were compared using ANOVA followed by Tukey's test. Associations between qualitative variables were tested by Chi-square (χ2) or Fisher's exact test. In order to check for differences among groups and IPAQ domains, a generalized linear model with Gamma distribution was adjusted for values in METs. Results The OP group differed from the NBD group regarding age (61.8 ± 10.1 and 52.9 ± 5.4 years), percentage of participants with self-declared white ethnicity (43.9 and 28.0%), body mass index (BMI - 25.7 ± 5.4 and 30.9 ± 5.1 kg/m(2)), and time since menopause (15.5 ± 7.5 and 5.8 ± 4.5 years). Smoking rates were higher in the OP (55.6%) and NBD groups (33.3%) than in the osteopenia group (11.1%). Within the OP group, the rate of subjects with sedentary lifestyles was higher (42.6%), and time spent sitting was greater (344.3 ± 204.8 METs) than in the groups with osteopenia (20.0% and 300.9 ± 230.6 METs) and NBD (17.7% and 303

  5. Content determination of sodium glucuronic acid for injection by HPLC%HPLC法测定注射用葡醛酸钠的含量

    Institute of Scientific and Technical Information of China (English)

    韩芸; 蔡姗英; 王雪芹

    2015-01-01

    目的:建立测定注射用葡醛酸钠中葡醛酸钠含量的高效液相色谱方法.方法:依利特 Hypersil BDS C18柱(4.6 mm×250 mm,5μm);流动相:0.25%四丁基氢氧化铵溶液(用磷酸调节pH至5.0)⁃乙腈(95∶5);流速:1.0 mL/min;检测波长:210 nm.结果:葡醛酸钠在0.25~2.01 g/L范围内线性关系良好, r=1.000,平均回收率为99.4%(n=9),定量限为0.80μg.结论:该方法灵敏、准确、专属性高,可用于注射用葡醛酸钠的质量控制.%AIM:To establish the high performance liquid chro⁃matography ( HPLC) method for quantifying the contents of sodi⁃um glucuronic acid for injection. METHODS: A Elite Hypersil BDS C18 column ( 4. 6 mm × 250 mm, 5 μm ) was used with 0.25% tetrabutyl⁃ammoium hydroxide solution ( pH adjusted to 5.0 with phosphoric acid)⁃acetonitrile (95 ∶5) as mobile phase. The flow rate was 1.0 mL/min, and detection wavelength was 210 nm. RESULTS:The calibration curve was linear ( r=1.000) in the range of 0.25~2.01 g/L for sodium glucuronic acid, with the average recovery rate being 99.4% (n=9). The LOD was 0.80μg. CONCLUSION: HPLC method is sensitive, reliable and specific, and can be used for the quality control of sodium glucu⁃ronic acid.

  6. Measurements of fast neutrons by bubble detectors

    International Nuclear Information System (INIS)

    Neutron bubble detectors have been studied using Am-Be and D-D neuron sources, which give limited energy information. The Bubble Detector Spectrometer (BDS) have six different energy thresholds ranging from 10 KeV to 10 Mev. The number of bubbles obtained in each measurement is related to the dose (standardized response R) equivalent neutrons through sensitivity (b / μSv) and also with the neutron flux (neutrons per unit area) through a relationship that provided by the manufacturer. Bubble detectors were used with six different answers (0.11 b/ μSv, 0093 b/μSv, 0.14 b/μSv, 0.17 b/μSv, 0051 b/μSv). To test the response of the detectors (BDS) radiate a set of six of them with different energy threshold, with a source of Am-Be, placing them at a distance of one meter from it for a few minutes. Also, exposed to dense plasma focus Fuego Nuevo II (FN-II FPD) of ICN-UNAM, apparatus which produces fusion plasma, generating neutrons by nuclear reactions of neutrons whose energy emitting is 2.45 MeV. In this case the detectors were placed at a distance of 50 cm from the pinch at 90° this was done for a certain number of shots. In both cases, the standard response is reported (Dose in μSv) for each of the six detectors representing an energy range, this response is given by the expression Ri= Bi / Si where Bi is the number of bubbles formed in each and the detector sensitivity (Si) is given for each detector in (b / μSv). Also, reported for both cases, the detected neutron flux (n cm−2), by a given ratio and the response involves both standardized R, as the average cross section sigma. The results obtained have been compared with the spectrum of Am-Be source. From these measurements it can be concluded that with a combination of bubble detectors, with different responses is possible to measure the equivalent dose in a range of 10 to 100 μSv fields mixed neutron and gamma, and pulsed generated fusion devices

  7. Paramagnetic oxotungsten(V) complexes containing the hydrotris(3,5-dimethylpyrazol-1-yl)borate ligand.

    Science.gov (United States)

    Sproules, Stephen; Eagle, Aston A; Taylor, Michelle K; Gable, Robert W; White, Jonathan M; Young, Charles G

    2011-05-16

    Sky-blue Tp*WOCl(2) has been synthesized from the high-yielding reaction of Tp*WO(2)Cl with boron trichloride in refluxing toluene. Dark-red Tp*WOI(2) was prepared via thermal decarbonylation followed by aerial oxidation of Tp*WI(CO)(3) in acetonitrile. From these precursors, an extensive series of mononuclear tungstenyl complexes, Tp*WOXY [X = Cl(-), Y = OPh(-), SPh(-); X = Y = OPh(-), 2-(n-propyl)phenolate (PP(-)), SPh(-), SePh(-); XY = toluene-3,4-dithiolate (tdt(2-)), quinoxaline-2,3-dithiolate (qdt(2-)), benzene-1,2-diselenolate (bds(2-)); Tp* = hydrotris(3,5-dimethylpyrazol-1-yl)borate], was prepared by metathesis with the respective alkali-metal salt of X(-)/XY(2-) or (NHEt(3))(2)(qdt). The complexes were characterized by microanalysis, mass spectrometry, electrochemistry, IR, electron paramagnetic resonance (EPR), and electronic absorption spectroscopies, and X-ray crystallography (for X = Y = OPh(-), PP(-), SPh(-); XY = bds(2-)). The six-coordinate, distorted-octahedral tungsten centers are coordinated by terminal oxo [W≡O = 1.689(6)-1.704(3) Å], tridentate Tp*, and monodentate or bidentate O/S/Se-donor ligands. Spin Hamiltonian parameters derived from the simulation of fluid-solution X-band EPR spectra revealed that the soft-donor S/Se ligand complexes had larger g values and smaller (183)W hyperfine coupling constants than the less covalent hard-donor O/Cl species. The former showed low-energy ligand-to-metal charge-transfer bands in the near-IR region of their electronic absorption spectra. These oxotungsten(V) complexes display lower reduction potentials than their molybdenum counterparts, underscoring the preference of tungsten for higher oxidation states. Furthermore, the protonation of the pyrazine nitrogen atoms of the qdt(2-) ligand has been examined by spectroelectrochemistry; the product of the one-electron reduction of [Tp*WO(qdtH)](+) revealed usually intense low-energy bands. PMID:21495687

  8. Establishment of HPLC Fingerprint of Ramulus Uncariae Cum Uncis%钩藤HPLC指纹图谱的构建

    Institute of Scientific and Technical Information of China (English)

    何昱; 黄家卫; 杨维

    2011-01-01

    OBJECTIVE: To establish the HPLC fingerprint of Ramulus Uncariae Cum Uncis, and to provide objective basis for the quality control of Ramulus Uncariae Cum Uncis based on the results of the content determination of rhynchophylline and isorhynchophylline. METHODS: The determination was performed on Hypersil BDS C18(250 mm×4.6 mm, 5 μm) column with the mobile phase consisted of methanol-0.02% triethylamine-water (gradient elution). The flow rate was 1.0 mL· min-1 and UV detection wavelength was 254 nm. RESULTS: The HPLC fingerprints of Ramulus Uncariae Cum Uncis were established according to the chromatographic data of 10 batches of samples. The results of similarity evaluation and principle component analysis (PCA)were favorable. CONCLUSION: Established fingerprint reflects the inherent character of Ramulus Uncariae Cum Uncis and can be used for the quality evaluation of it.%目的:建立钩藤药材的高效液相色谱(HPLC)指纹图谱,并结合钩藤碱和异钩藤碱的含量测定结果,为钩藤药材的质量控制提供客观依据.方法:色谱柱为依利特 Hypersil BDS C18(250 mm×4.6 mm,5μm),流动相为甲醇-含0.02%三乙胺的水(梯度洗脱),流速为1.0mL·min-1,紫外检测波长为254nm.结果:依照10个批次样品的色谱数据构建起钩藤药材的HPLC指纹图谱,相似度评价和主成分分析的结果良好.结论:所构建的指纹图谱可以反映钩藤药材的内在组成,作为其质量评价的标准.

  9. The Effects of a Brief Acceptance-based Behavior Therapy vs. Traditional Cognitive Behavior Therapy for Public Speaking Anxiety: Differential Effects on Performance and Verbal Working Memory

    Science.gov (United States)

    Glassman, Lisa Hayley

    Individuals with public speaking phobia experience fear and avoidance that can cause extreme distress, impaired speaking performance, and associated problems in psychosocial functioning. Most extant interventions for public speaking phobia focus on the reduction of anxiety and avoidance, but neglect performance. Additionally, very little is known about the relationship between verbal working memory and social performance under conditions of high anxiety. The current study compared the efficacy of two cognitive behavioral treatments, traditional Cognitive Behavioral Therapy (tCBT) and acceptance-based behavior therapy (ABBT), in enhancing public speaking performance via coping with anxiety. Verbal working memory performance, as measured by the backwards digit span (BDS), was measured to explore the relationships between treatment type, anxiety, performance, and verbal working memory. We randomized 30 individuals with high public speaking anxiety to a 90-minute ABBT or tCBT intervention. As this pilot study was underpowered, results are examined in terms of effect sizes as well as statistical significance. Assessments took place at pre and post-intervention and included self-rated and objective anxiety measurements, a behavioral assessment, ABBT and tCBT process measures, and backwards digit span verbal working memory tests. In order to examine verbal working memory during different levels of anxiety and performance pressure, we gave each participant a backwards digit span task three times during each assessment: once under calm conditions, then again while experiencing anticipatory anxiety, and finally under conditions of acute social performance anxiety in front of an audience. Participants were asked to give a video-recorded speech in front of the audience at pre- and post-intervention to examine speech performance. Results indicated that all participants experienced a very large and statistically significant decrease in anxiety (both during the speech and BDS

  10. 25-羟维生素D3在幼年特发性关节炎患儿血清中的表达水平及意义%Expression level and significance of 25-hydroxy vitamin D3 in serum of children with juvenile idiopath-ic arthritis

    Institute of Scientific and Technical Information of China (English)

    马志超; 阮和球; 黄白丽

    2016-01-01

    Objective To study the expression and significance of 25-hydroxy vitamin D3 [25(OH) D3] in serum of children with juvenile idiopathic arthritis (JIA). Methods 78 cases of JIA children and 80 cases healthy children were collected from January 2014 to June 2015 in our hospital , and the concentration of 25 (OH)D3 in serum was detected by Roche diagnostic kit. The results were analyzed statistical ly. Results There were statistical significance in the difference of 25 (OH)D3 level among different types of JIA groups and control group(P<0.05). The 25(OH)D3 level of different types of JIA groups were all lower than that of control group, and the differences all had statistical significance(Pall<0.05). There were statistical significance in the differences of 25(OH)D3 level between each two types of JIA groups(Pall<0.05). The lack rate of generalized type JIA group (77.8%) was significantly higher than the other type groups , while the normal rate of oligoartic-ular JIA (62.5%) was higher than that of the systemic JIA group (11.1%) and the polyarticular JIA group (14.3%). Conclusion JIA children exist VitD deficiency, low levels of VitD and JIA have a certain correla-tion. Detection of VitD content may contribute to the diagnosis and treatment of JIA.%目的探讨25-羟维生素D3[25-hydroxy vitamin D3,25(OH)D3]在幼年特发性关节炎(ju-venile idiopathic arthritis, JIA)患儿血清中的表达水平及意义。方法收集我院2014年1月至2015年6月确诊的JIA患儿78例以及同期健康体检儿童80例,采用罗氏诊断试剂盒检测受检儿童血清中的25(OH)D3水平,对检测结果进行统计学分析。结果不同类型JIA组及对照组儿童间血清25(OH)D3检测结果差异有统计学意义(P<0.05);所有JIA组患儿血清25(OH)D3检测结果均明显低于对照组,且差异均有统计学意义(P均<0.05);不同类型的JIA组间血清25(OH)D3检测结果两两比较,差异

  11. Differential Responses to Simulated Precipitation Exhibited by a Typical Shrub and a Herb Coexisted in Hunshandak Sandy Land%浑善达克沙地典型灌木和草本植物对模拟降雨的不同反应

    Institute of Scientific and Technical Information of China (English)

    牛书丽; 彭羽; 蒋高明; 李永庚; 高雷鸣; 刘美珍; 崔洪霞; 丁莉

    2004-01-01

    为了探讨不同生活型对瞬时降雨的适应策略,比较了浑善达克沙地常见灌木羊柴(Hedysarum fruticosum Pall.)和其共生草本植物猪毛菜(Salsola callina Y.L. Chang)在降雨解除干旱后的生理生态反应.光合速率(Pn)、蒸腾速率(E)、气孔导度(gs)、PSⅡ最大光化学效率(Fv/Fm)和叶片水势(ψleaf)均随着模拟降雨量的增加而增大;羊柴的水分利用效率(WUE)随降雨量的变化不大,而猪毛菜的WUE却随降雨量的增加一直处于下降趋势.两种植物的Pn和Fv/Fm都在雨后3 d完全恢复,而gs和ψleaf却提前1或2 d恢复,这说明气孔和非气孔因素综合限制了羊柴和猪毛菜的同化速率.两种植物对模拟降雨量的反应方式不同,15 mm的雨量就使羊柴的Pn、E和gs达到最大值,而猪毛菜却随着雨量的增加一直增大.我们认为,羊柴和猪毛菜对于模拟降雨的反应在时间上具有同步性,但对雨量的反应方式却不一致,猪毛菜对水分的利用不经济且瞬时反应,而羊柴可以被认为是节约型用水植物.%To assess the ecophysiological responses and adaptive strategies to rainfall exhibited by different plant functional types, we compared gas exchange, leaf water potential (ψleaf) and PSⅡ photochemical efficiency (Fv/Fm) between Hedysarum fruticosum Pall. (shrub) and Salsola collina Y. L. Chang (herb) under a series of simulated rainfalls. The experiment was conducted in Hunshandak Sandy Land,North China. The values of net photosynthetic rate (Pn), transpiration rate (E), stomatai conductance (gs),Fv/Fm and ψleaf always elevated with the increasing amount of simulated rainfall. Whereas water use efficiency (WUE) maintained constant in /. fruticosum while always decreased in S. collina. Both species fully recovered their Pn and Fv/Fm 3 d after rainfall, while gs and ψleaf recovered only within 2 d. However,the response patterns were obviously different.H. fruticosu promote its physiological traits within 5

  12. Efficiency of different breathing filters on peak inspiratory pressure in mechanical ventilation%不同呼吸过滤器在机械通气中对气道峰压的影响

    Institute of Scientific and Technical Information of China (English)

    李璐; 赵砚丽; 韩广彦

    2008-01-01

    Objective To comprehensively evaluate the influence on peak inspiratory pressure(PIP)in mechanical ventilation.Methods Sixty patients,aged 18-65 years old,operating time about three hours,who underwent elective abdominal surgery in general anesthesia were enrolled.All patients had no breathing system diseases and heart failure diseases.All patients were randomly divided into four groups(n=15):PALL BB 25S(P)group,DAR 352/5805(D)group,Vital signs 5702 TMP(V1)group and Vital signs 5708 HEPA(V2)group.PIP scale was recorded at five minutes before applying BF,five minutes after applying BF and the finishing time of operation.Results There was no significant difference among four groups at the different time(P>0.05).But at the t2 and t3 time,the value of PIP was higher than its former time in the same group(P<0.05).Conclusions Using breathing filter has little influence on PIP.But its change is permitted in clinical practice.%目的 综合性评价不同类型呼吸过滤器(breathing filter,BF)在机械通气中对气道峰压(peak inspiratory pressure,PIP)的影响.方法 选择择期全麻下行腹部手术患者60例,年龄18~65 岁,手术时间约3 h,既往无呼吸系统疾患及心力衰竭病史,随机分为4组(每组15例):PALL BB 25S(P)组、DAR 352/5805(D)组、Vital signs 5702 TMP(V1)组和Vital signs 5708 HEPA(V2)组,记录应用BF前5 min (t1)、应用BF后5 min(t2)及术毕即刻(t3)时的PIP值.结果 4组在同一时点比较中PIP值差异无统计学意义(P>0.05);4组组内t2与t1时刻比较以及t3与t2时刻比较PIP值升高差异均有统计学意义(P<0.05).结论 在机械通气中使用呼吸过滤器会增加一定程度的PIP,但PIP的实际测量值均在临床允许范围之内.

  13. Observation on the Therapeutic Effect of Shengmaidingxin Decoction and Digoxin in the Management of Ventricular rate of Persistent Atrial Fibrillation%生脉定心汤联合地高辛控制持续性心房颤动心室率的疗效观察

    Institute of Scientific and Technical Information of China (English)

    黄斌

    2011-01-01

    Objective: To observe the clinical efficacy and safety of shengmaidingxin decoction and digoxin in the management of ventricular tachyarrhythmia related to persistent atrial fibrillation. Methods ;66 patients with persistent atrial fibrillation received digoxin 0.25 rag / d for 1 week,Heart rate was still greater than 100 times / min in the daily light physical activity. They randomly divided into 2 groups; Control group (32 patients )received digoxin and metoprolol .Observation group( 34 received) received digoxin and shengmaidingxin decoction . Two groups were treated for 4 weeks. Ventricular rate and exercise tolerance and side effects of 2 groups were observed before and after treatment. Results; Results After treatment, there was no significant difference between the control group and the observation group in the efficacy of the management of ventricular rate (\\2 =0- 8580, P > 0. 05) .Resting heart rate,maximum heart rate after exercise,exercise duration,maximal exercise distance etc. Four indicators in 2 groups showed no significant difference (Pall > 0. 05), they were comparable. Four indicators of 2 groups were significantly improved compared with before treatment (Pall 0. 05). The adverse reaction rates of the observation group (2/34 =5.9%) was significantly lower than the control group ( 9/23 =39. 1%) (x2 = 5.8720, P < 0. 05). Conclusion; Shengmaidingxin decoction combined with digoxin could effectively control the ventricular rate in atrial fibrillation, increased exercise tolerance, and adverse reactions was few and mild.%目的:观察生脉定心汤联合地高辛控制持续性心房颤动快速心室率的疗效和安全性.方法:选择66例持续性房颤患者给予地高辛0.25mg/d治疗1周后,日常轻体力活动时心率仍大于100次/min.随机分为两组:对照组32例应用地高辛+美托洛尔口服,观察组34例应用地高辛+生脉定心汤口服,两组均治疗4周.观察两组治疗前后心室率、运动耐量及不良反应

  14. 天山北坡伊犁绢蒿荒漠不同退化阶段草地特征分析%Characteristic Analysis of Seriphidium transillense (Poljak.) Poljak. Desert Grasslands at Different Degraded Stages in the Northern Tianshan Mountains

    Institute of Scientific and Technical Information of China (English)

    刘洪来; 朱进忠; 靳瑰丽; 范燕敏; 王彩虹

    2009-01-01

    In the mid-1980s, grasslands owned by the state were contracted to families for 30 to 50 years, and then increased livestock populations imposed heavy grazing pressure on Seriphidium transillense (Poljak.) Poljak. desert grasslands. Three sites with different degradation degrees were chosen on the northern slopes in Tianshan Mountains in western China to analyze the characteristics of plant populations, soil properties, and their relationships with different degradation stages. The results demonstrate that the dominant species shifted away from S. transillense into Petrosimonia sibirica (Pall.) Bunge which adopted r-strategy to produce innumerable seeds and then formed large population and consequently protected the grassland from completely collapse. The frequency, cover, yield, and density of S. transillense gradually decreased while P. sibirica increased and the feeding value of grassland became worse along with the degradation degrees. The compositional shift towards smaller, unpalatable and more ephemeral species was indicative of grassland degradation. The degradation of grassland vegetation was not in accordance with soil degradation. The surface soil had a trend of becoming coarse with the degraded degrees; however, the soil organic matter and total nitrogen steadily increased and reached the climax in over-degradation areas where the dung accumulation was the main reason for high soil nutrient content.%对天山北坡不同退化阶段伊犁绢蒿(Seriphidium transillense (Poljak.) Poljak.)荒漠草地植被特征和土壤特性进行分析,以期为该地区的草地恢复提供理论依据.结果表明:随着草地退化程度的加剧,伊犁绢蒿荒漠的优势种逐渐被叉毛蓬(Petrosimonia sibirica (Pall.) Bunge)替代;地带性植被伊犁绢蒿的频度、盖度、生物量和密度随着草地退化程度的加剧逐渐降低,而叉毛蓬却呈相反趋势;叉毛蓬种群在扩繁时采用"r"对策,产生大量种子迅速占

  15. HPLC法同时测定酮康他索软膏中酮康唑和丙酸氯倍他索的含量%HPLC Determination of Ketoconazole and Clobetasol Propionate in Clonazole Cream

    Institute of Scientific and Technical Information of China (English)

    廖辉怡; 申放; 黄里靖

    2002-01-01

    目的:采用高效液相色谱法测定酮康他索软膏中酮康唑、丙酸氯倍他索的含量.方法:色谱柱为Hypersil BDS C18和Kromasil C18;流动相为0.02 mol*L-1磷酸氢二钠溶液-甲醇(30∶ 70),并用稀磷酸调节pH至6.9±0.1;紫外检测器,检测波长为239 nm.结果:在建立的色谱条件下,酮康唑及丙酸氯倍他索与有关杂质能有效地分离.酮康唑进样量在3.2~28.8 μg,丙酸氯倍他索在0.08~0.72 μg范围内与峰面积呈良好线性关系,相关系数依次为0.999 7,0.999 9,回收率依次为100.8%,101.3%.结论:本法精密度好,结果准确可靠.

  16. Effect of low-level laser therapy on repair of the bone compromised by radiotherapy.

    Science.gov (United States)

    Batista, Jonas D; Zanetta-Barbosa, Darceny; Cardoso, Sérgio V; Dechichi, Paula; Rocha, Flaviana S; Pagnoncelli, Rogério M

    2014-11-01

    Radiotherapy (RDT) is commonly used for cancer treatment, but high doses of ionizing radiation can directly affect healthy tissues. Positive biological effects of low-level laser therapy (LLLT) on bone repair have been demonstrated; however, this effect on surgical defects of bone previously compromised by radiotherapy has not been evaluated. The aim of this study was to investigate the influence of LLLT (λ = 830 nm) in femur repair after ionizing radiation. Twenty Wistar rats were divided into four groups: control group (GC, n = 5) creation of bone defects (BDs) only; laser group (GL), with BD and LLLT (n = 5); radiotherapy group (GR), submitted to RDT and BD (n = 5); and radiotherapy and laser group (GRL), submitted to RDT, BD, and LLLT (n = 5). GL and GRL received punctual laser application (DE = 210 J/cm(2), P = 50 mW, t = 120 s, and beam diameter of 0.04 cm(2)) immediately after surgery, with 48-h interval during 7 days. Animals were euthanized at 7 days after surgery, and bone sections were evaluated morphometrically with conventional microscopy. Bone repair was only observed in nonirradiated bone, with significant improvement in GL in comparison to GC. GR and GRL did not present any bone neoformation. The result demonstrated a positive local biostimulative effect of LLLT in normal bone. However, LLLT was not able to revert the bone metabolic damage due to ionizing radiation.

  17. On Chaotic Nature of the Emerging European Forex Markets

    Directory of Open Access Journals (Sweden)

    Anoop S Kumar

    2014-06-01

    Full Text Available This study attempts to analyze the presence deterministic chaos in the forex markets of select European countries namely Bulgaria, Croatia, Czech Republic, Hungary Poland, Romania, Russia, Slovakia and Slovenia. Monthly NEER data ranging from jan-1994 to Dec-2013 is used for the purpose of analysis. A two step methodology is employed where in the first step, non-linear dependence structure in the underlying time series is verified using BDS test. The results show that all the markets under study exhibit non-linear dependence. In the next stage, it is enquired whether this non-linear behavior is due to the presence of chaotic dynamics in the markets. This is achieved by estimating Lyapunov exponents for the time series under analysis. An EGARCH (1, 1 filter is applied to see if the non-linearity could be explained by a GARCH process. From the Lyapunov exponent values, it is found that the GARCH process is unable to explain the forex markets behavior in a satisfying manner. It is concluded that the forex markets under study exhibit deterministic chaotic behavior.

  18. Temperature constraints on the coldest brown dwarf known WISE 0855-0714

    CERN Document Server

    Beamín, J C; Bayo, A; Mužić, K; Boffin, H M J; Allard, F; Homeier, D; Minniti, D; Gromadzki, M; Kurtev, R; Lodieu, N; Martin, E L; Mendez, R A

    2014-01-01

    Context. Nearby isolated planetary mass objects are beginning to be discovered, but their individual properties are poorly constrained because their low surface temperatures and strong molecular self-absorption make them extremely faint. Aims. We aimed to detect the near infrared emission of the coldest brown dwarf (BD) found so far WISE0855$-$0714, located $\\sim$2.2 pc away, and to improve its temperature estimate (T$_{\\rm eff}$= 225-260 K) from a comparison with state of the art models of BD atmospheres. Methods. We observed the field containing WISE0855-0714 with HAWK-I at the VLT in the $Y$ band. For BDs with T$_{\\rm eff}24.4 mag at 3-$\\sigma$ level, leading to Y-[4.5]>10.5. Combining this limit with previous detections and upper limits at other wavelengths, WISE0855-0714 is confirmed as the reddest BD detected. We applied spectral energy distribution fitting with collections of models from two independent groups for extremely cool BD atmospheres leading to an effective temperature of T$_{\\rm eff}<$250...

  19. Stress Degradation Behavior of Paliperidone, an Antipsychotic Drug, and Development of Suitable Stability-Indicating RP-LC Method

    Directory of Open Access Journals (Sweden)

    Sanjay A. Jadhav

    2011-01-01

    Full Text Available A new, simple, rapid, and stability-indicating reversed phase liquid chromatographic (RP-LC method for the determination of both assay and related substances in paliperidone has been developed and validated. During the forced degradation at hydrolysis, oxidative, photolytic, and thermal stressed conditions, the degradation was observed in the oxidative and acid stress conditions. Five process-related impurities (Imp-A to Imp-E in test sample of paliperidone have been detected using newly developed RP-LC method. Among the five, Imp-C and Imp-D were found to be degrdants. Good resolution between the peaks corresponding to degradation and process-related impurities from the analyte was achieved on a Hypersil BDS C18 (250×4.6 mm, 5 μm column. The stress samples were assayed against a qualified reference standard, and the mass balance was found to be close to 99.0%. The method was validated as per ICH guideline and was found to be robust. The proposed RP-LC method was successfully applied to the analysis of commercial formulation and was found to be specific and selective.

  20. Deviation from Alday-Maldacena duality for wavy circle

    International Nuclear Information System (INIS)

    Alday-Maldacena conjecture is stated in this paper that the area AΠ of the minimal surface in AdS5 space with a boundary Π, located in Euclidean space at infinity of AdS5, coincides with a double integral DΠ along Π, the Abelian Wilson average in an auxiliary dual model. This comes from Alday and Maldacena's original proposal and the BDS conjecture on the extrapolation of the MHV amplitudes. The boundary Π is a polygon formed by momenta of n external light-like particles in N=4 SYM theory, and in a certain n=∞ limit it can be substituted by an arbitrary smooth curve (wavy circle). The Alday-Maldacena conjecture is known to be violated for n>5, when it fails to be supported by the peculiar global dual conformal invariance, however, the structure of deviations remains obscure. The case of wavy lines can appear more convenient for analysis of these deviations due to the systematic method developed in [H. Itoyama, A. Mironov, A. Morozov, Anomaly in n=∞ Alday-Maldacena duality for wavy circle, JHEP 0807 (2008) 024, (arXiv:0803.1547)] for (perturbative) evaluation of minimal areas, which is not yet available in the presence of angles at finite n. We correct a mistake in that paper and explicitly evaluate the h2h-bar2 terms, where the first deviation from the Alday-Maldacena duality arises for the wavy circle.

  1. KV1 and KV3 Potassium Channels Identified at Presynaptic Terminals of the Corticostriatal Synapses in Rat

    Science.gov (United States)

    Meneses, David; Vega, Ana V.; Torres-Cruz, Francisco Miguel; Barral, Jaime

    2016-01-01

    In the last years it has been increasingly clear that KV-channel activity modulates neurotransmitter release. The subcellular localization and composition of potassium channels are crucial to understanding its influence on neurotransmitter release. To investigate the role of KV in corticostriatal synapses modulation, we combined extracellular recording of population-spike and pharmacological blockage with specific and nonspecific blockers to identify several families of KV channels. We induced paired-pulse facilitation (PPF) and studied the changes in paired-pulse ratio (PPR) before and after the addition of specific KV blockers to determine whether particular KV subtypes were located pre- or postsynaptically. Initially, the presence of KV channels was tested by exposing brain slices to tetraethylammonium or 4-aminopyridine; in both cases we observed a decrease in PPR that was dose dependent. Further experiments with tityustoxin, margatoxin, hongotoxin, agitoxin, dendrotoxin, and BDS-I toxins all rendered a reduction in PPR. In contrast heteropodatoxin and phrixotoxin had no effect. Our results reveal that corticostriatal presynaptic KV channels have a complex stoichiometry, including heterologous combinations KV1.1, KV1.2, KV1.3, and KV1.6 isoforms, as well as KV3.4, but not KV4 channels. The variety of KV channels offers a wide spectrum of possibilities to regulate neurotransmitter release, providing fine-tuning mechanisms to modulate synaptic strength. PMID:27379187

  2. ATF2 Proposal v. 2

    CERN Document Server

    Grishanov, B I; Alabau-Pons, M; Angal-Kalinin, Deepa; Appleby, R; Araki, S; Bailey, I; Bambade, P; Bane, Karl Leopold Freitag; Barlow, R; Blair, G A; Bolzon, B; Boorman, G; Bosco, A; Brachmann, A; Braun, Hans Heinrich; Burrows, P N; Carter, J; Choi, J; Christian, Glenn B; Clarke, C; Dabiri-Khah, A; Dadoun, O; Danagulyan, S; Delerue, N; Dixit, S; Driouichi, C; Elsen E; Gao, J; Geffroy, N; Gronberg, J; Hartin, Anthony F; Hayano, H; Higashi, Y; Himel, T; Honda, Y; Howell, D; Huang, J Y; Iwashita, Y; Jenner, L; Jones, J; Jones, R; Jérémie, A; Kalinin, A; Kanazawa, K; Kang, H S; Karyotakis, Yu; Kim, E S; Kim, S; Komamiya, S; Kourevlev, German Yu; Kubo, K; Kumada, M; Kume, T; Kuriki, M; Kuroda, S; Liu, W; Logatchev, P V; Lyapin, A; Malton, S; Markiewicz, T W; Masuzawa, M; Mihara, T; Miller, D J; Molloy, S; Mtingwa, S; Naito, T; Nan-Phinney, Y; Napoly, O; Nelson, J; Okugi, T; Payet, J; Pei, G X; Pivi, M T F; Podgorny, F; Price, M; Raubenheimer, T O; Reichold, A; Ross, M; Sanuki, T; Schulte, Daniel; Seryi, R A; Solyak, N; Soo Ko In; Spencer, C M; Suehara, T; Sugahara, R; Takahashi, T; Takashi-Boogert, S; Tauchi, T; Telnov, Valery I; Tenenbaum, P G; Terunuma, N; Toge, N; Torrence, E; Urakawa, J; Urner, D; Vogel, V; Walker, N; Wang, J Q; Wendt, M; White, G; Wing, M; Wolski, A; Woodley, M; Yamaoka, H; Yokoya, K; Zimmermann, Frank

    2006-01-01

    For achieving the high luminosity required at the International Linear Collider (ILC), it is critical to focus the beams to nanometer size with the ILC Beam Delivery System (BDS), and to maintain the beam collision with a nanometer-scale stability. To establish the technologies associated with this ultra-high precision beam handling, it has been proposed to implement an ILC-like final focus optics in an extension of the existing extraction beamline of ATF at KEK. The ATF is considered to be the best platform for this exercise, since it provides an adequate ultra-low emittance electron beam in a manner dedicated to the development of ILC. The two major goals for this facility, called ATF2, are : (A) Achievement of a 37 nm beam size, and (B) control of beam position down to 2 nm level. The scientific justification for the ATF2 project and its technical design have been described in Volume 1 of the ATF2 Proposal [1]. We present here Volume 2 of the ATF2 Proposal, in which we present specifics of the construction...

  3. Long-Implosion-Time Z-pinch Experiments with Deuterium Gas-Puffs on the GIT-12 Generator

    Science.gov (United States)

    Klir, D.; Kubes, P.; Rezac, K.; Cikhardt, J.; Kravarik, J.; Shishlov, A.; Labetsky, A.; Fursov, F.; Kokshenev, V.; Kovalchuk, B.; Kurmaev, N.; Ratakhin, N.

    2012-10-01

    Experiments with deuterium triple shell gas-puffs have been carried out on the GIT-12 generator at the IHCE in Tomsk. Outer, middle, and inner nozzle diameters were 160 mm, 80 mm and 30 mm, respectively. The influence of the mass of deuterium shells on neutron emission times, neutron yields and neutron spectra was studied. The linear mass density of deuterium varied between 50 and 270 μg/cm. Gas puffs imploded onto the axis before the peak of a generator current at 700-1100 ns. The first neutron peak occurred during the stagnation. Most of the neutrons were emitted during the second neutron pulse after the development of instabilities. In lower mass gas puffs, neutron energies of up to 4.4 MeV gave the evidence of 1 MeV deuterons. The peak neutron yield from D(d,n)^3He reactions reached 3x10^11 on a current level of 2.5 MA. Secondary DT neutrons were measured by BDS-10000 bubble detectors. An average neutron yield ratio Y>10 MeV/Y2.5 MeV exceeded (6±3)x10-4. Ne-Ne-D2 and Ne-D2-D2 gas puffs produced 3 times lower neutron yields but the first neutron pulse during the stagnation was nearly the same as with D2-D2-D2 gas puffs.

  4. HPLC法测定地锦草灌肠液中苦参碱的含量%Determination of grass enema Verbena matrine in by HPLC

    Institute of Scientific and Technical Information of China (English)

    佘永红; 李璞; 周顺

    2010-01-01

    目的:建立地锦草灌肠液中苦参碱的含量测定.方法:采用HPLC法,色谱柱为BDS Hypersil C18柱,流动相为甲醇-乙腈-三乙胺-磷酸盐缓冲液,流速为1.0 mL·min-1,检测波长为220 nm,柱温为室温,进样量为20 μL.结果:苦参碱在0.3616-4.338 μg范围内呈良好的线形关系(r=0.9996),平均回收率为97.7%,RSD%为0.77%(n=6).结论:该方法简便,准确,重现性好,可用于地锦草灌肠液的质量控制.

  5. The bimodal initial mass function in the Orion Nebula Cloud

    CERN Document Server

    Drass, H; Chini, R; Bayo, A; Hackstein, M; Hoffmeister, V; Godoy, N; Vogt, N

    2016-01-01

    Due to its youth, proximity and richness the Orion Nebula Cloud (ONC) is an ideal testbed to obtain a comprehensive view on the Initial Mass Function (IMF) down to the planetary mass regime. Using the HAWK-I camera at the VLT, we have obtained an unprecedented deep and wide near-infrared JHK mosaic of the ONC (90% completeness at K~19.0mag, 22'x28). Applying the most recent isochrones and accounting for the contamination of background stars and galaxies, we find that ONC's IMF is bimodal with distinct peaks at about 0.25 and 0.025 M_sun separated by a pronounced dip at the hydrogen burning limit (0.08 M_sun), with a depth of about a factor 2-3 below the log-normal distribution. Apart from ~920 low-mass stars (M 0.005 M_sun, hence about ten times more substellar candidates than known before. The substellar IMF peak at 0.025 M_sun could be caused by BDs and IPMOs which have been ejected from multiple systems during the early star-formation process or from circumstellar disks.

  6. Development and Validation of an HPLC Method for Simultaneous Quantification of Clopidogrel Bisulfate, Its Carboxylic Acid Metabolite, and Atorvastatin in Human Plasma: Application to a Pharmacokinetic Study

    Directory of Open Access Journals (Sweden)

    Octavian Croitoru

    2015-01-01

    Full Text Available A simple, sensitive, and specific reversed phase liquid chromatographic method was developed and validated for simultaneous quantification of clopidogrel, its carboxylic acid metabolite, and atorvastatin in human serum. Plasma samples were deproteinized with acetonitrile and ibuprofen was chosen as internal standard. Chromatographic separation was performed on an BDS Hypersil C18 column (250 × 4.6 mm; 5 μm via gradient elution with mobile phase consisting of 10 mM phosphoric acid (sodium buffer solution (pH = 2.6 adjusted with 85% orthophosphoric acid : acetonitrile : methanol with flow rate of 1 mL·min−1. Detection was achieved with PDA detector at 220 nm. The method was validated in terms of linearity, sensitivity, precision, accuracy, limit of quantification, and stability tests. Calibration curves of the analytes were found to be linear in the range of 0.008–2 μg·mL−1 for clopidogrel, 0.01–4 μg·mL−1 for its carboxylic acid metabolite, and 0.005–2.5 μg·mL−1 for atorvastatin. The results of accuracy (as recovery with ibuprofen as internal standard were in the range of 96–98% for clopidogrel, 94–98% for its carboxylic acid metabolite, and 90–99% for atorvastatin, respectively.

  7. HPLC Determination of Fexofenadine in Human Plasma For Therapeutic Drug Monitoring and Pharmacokinetic Studies.

    Science.gov (United States)

    Helmy, S A; El Bedaiwy, H M

    2016-07-01

    A simple and sensitive method was developed for fexofenadine determination in human plasma by liquid chromatography with ultraviolet detection. Satisfactory separation was achieved on a Hypersil® BDS C18 column (250 × 4.6 mm, 5μm) using a mobile phase comprising 20 mm sodium dihydrogen phosphate-2 hydrate (pH adjusted to 3 with phosphoric acid)-acetonitrile at a ratio of 52:48, v/v. The elution was isocratic at ambient temperature with a flow rate of 1.0 mL/min. The UV detector was set at 215 nm for the drug and 330 nm for the internal standared (tinidazole). The total time for a chromatographic separation was ~6.5 min. Linearity was demonstrated over the concentration range 0.01-4 μg/mL. The observed within- and between-day assay precision ranged from 0.346 to 13.6%; accuracy varied between 100.4 and 111.2%. This method was successfully applied for therapeutic drug monitoring in patients treated with clinical doses of fexofenadine and for pharmacokinetic studies. Copyright © 2015 John Wiley & Sons, Ltd. PMID:26577375

  8. Undergraduate dental education in New Zealand: 2007-2009 final-year student feedback on clinical learning environments.

    Science.gov (United States)

    Anderson, Vivienne R; Rich, Alison M; Seymour, Gregory J

    2011-09-01

    Dental education is a unique form of health professional education. This is because the clinical training component largely occurs within the dental school and involves students carrying out irreversible patient interventions early in their education. Perhaps not surprisingly, previous research indicates that dental education (and particularly the clinical component) is stressful for many students. In their responses to an annual clinical learning environment survey, final-year Bachelor of Dental Surgery (BDS) students at the University of Otago have suggested that teaching staff play a key role in mitigating or compounding stressors associated with students' clinical work. In 2007-2009 questionnaire responses, students identified the kinds of staff feedback which they found constructive or unhelpful while working in patient clinic settings, described their responses to feedback received, and identified ways in which students' clinical learning experiences might be improved. This paper outlines 2007-2009 University of Otago Faculty of Dentistry clinical learning environment survey findings, and relates these to the literature on effective teaching and clinical teaching. It then describes programmatic changes and research initiatives developed in response to student feedback. PMID:21957835

  9. Neutron production in deuterium gas-puff z-pinch with outer plasma shell at current of 3 MA

    Science.gov (United States)

    Cikhardt, J.; Klir, D.; Rezac, K.; Cikhardtova, B.; Kravarik, J.; Kubes, P.; Sila, O.; Shishlov, A. V.; Cherdizov, R. K.; Frusov, F. I.; Kokshenev, V. A.; Kurmaev, N. E.; Labetsky, A. Yu.; Ratakhin, N. A.; Dudkin, G. N.; Garapatsky, A. A.; Padalko, V. N.; Varlachev, V. A.; Turek, K.; Krasa, J.

    2015-11-01

    Z-pinch experiments at the current of about 3 MA were carried out on the GIT-12 generator. The outer plasma shell of deuterium gas-puff was generated by the system of 48 plasma guns. This configuration exhibits a high efficiency of the production of DD fusion neutrons with the yield of above 1012 neutrons produced in a single shot with the duration of about 20 ns. The maximum energy of the neutrons produced in this pulse exceeded 30 MeV. The neutron radiation was measured using scintillation TOF detectors, CR-39 nuclear track detectors, bubble detectors BD-PND and BDS-10000 and by several types of nuclear activation detectors. These diagnostic tools were used to measure the anisotropy of neutron fluence and neutron energy spectra. It allows us to estimate the total number of DD neutrons, the contribution of other nuclear reactions, the amount of scattered neutrons, and other parameters of neutron production. This work was supported by the MSMT grants LH13283, LD14089.

  10. $B_{s,d}-\\bar B_{s,d}$ mixings and $b\\to q (\\ga, \\ell \\bar \\ell)$ decays in private Higgs model

    CERN Document Server

    Benbrik, Rachid; Geng, Chao-Qiang

    2009-01-01

    We study the low energy phenomena induced by the lightest charged Higgs in the private Higgs (PH) model, in which each quark flavor is associated with a Higgs doublet. We show that the couplings of the charged Higgs scalars to fermions are fixed and the unknown parameters are only the masses and mixing elements of the charged Higgs scalars. As the charged Higgs masses satisfy with $M_bB_{d,s}$ mixings and the BR for $B\\to K^* \\ell^{+} \\ell^{-}$. We illustrate that the sign of the Wilson coefficient for $B\\to X_s \\ga$ can be different from that in the standard model, while this flipped sign can be displayed by the forward-backward asymmetry of $B\\to V \\ell^{+} \\ell^{-}$ with $V$ a vector meson. We also demonstra...

  11. Beak deviations in the skull of Franciscana dolphins Pontoporia blainvillei from Argentina.

    Science.gov (United States)

    Denuncio, Pablo; Panebianco, M Victoria; Del Castillo, Daniela; Rodríguez, Diego; Cappozzo, H Luis; Bastida, Ricardo

    2016-06-15

    The Franciscana dolphin Pontoporia blainvillei is characterized by a long rostrum, a feature that is shared with the families formerly classified as river dolphins (Pontoporiidae, Platanistidae, Iniidae, Lipotidae). Although there are occasional reports on the existence of beak deformations, very little published information exists describing this process. The object of the present study was to describe and quantify the beak anomalies of Franciscana dolphins from the coastal waters of Argentina. Of 239 skulls analyzed 12% showed beak deviations (BD), affecting the premaxillary-maxillary and dentary bones to different extents. The occurrence of BD in the dentary bone represented 58%, whereas premaxillary-maxillary BDs were observed in 14% of the studied specimens, while the complete rostrum (dentary, premaxillary and maxillary) was affected in 28% of the skulls. Dorsoventral axis BD was more frequent than lateral BD (48 and 38%, respectively), and double BD was only observed in the dentary bone. Most of the BD observed in this study could be classified as mild/moderate, and we assume that it did not affect the feeding activities of individuals; however, 2 specimens (dolphin in different ways. A more detailed and thorough study of these cranial anomalies is necessary.

  12. Research RP - HPLC determination of glaucocalyxin A in rat plasma and its pharmacokinetic and excretion%RP-HPLC法测定大鼠血浆中蓝萼甲素含量与药代动力学及排泄研究

    Institute of Scientific and Technical Information of China (English)

    曹露晔; 陈子君; 李云森; 李仪奎; 马越鸣; 金若敏

    2006-01-01

    目的:研究蓝萼甲素在大鼠体内的药代动力学过程及排泄过程并建立大鼠生物样品测定的高效液相色谱方法.方法:采用液液萃取的方法从生物样品中提取出蓝萼甲素后用Hypersil BDS C18(250 mm×4.6 mm,5μm)柱进行分离,流动相为甲醇-水(45∶55).结果:蓝萼甲素在大鼠体内静脉给药后药代动力学符合二房室模型.t1/2α和t1/2β分别为4.32 min和28.56min,12 h蓝萼甲素在尿、粪便中的排泄量分别为12.8%和23.8%,在10 h内胆汁中的排泄量为35.68%.结论:此方法快捷、灵敏、简便,适合于蓝萼甲素的药代动力学研究.

  13. Knowledge and attitude regarding Ebola virus disease among medical students of Rawalpindi: A preventable threat not yet confronted

    Science.gov (United States)

    Hisam, Aliya; Rana, Mariam Nadeem; Mahmood-Ur-Rahman

    2016-01-01

    Objective: To assess the knowledge and attitude regarding Ebola virus disease (EVD) among medical students of Rawalpindi. Methods: A descriptive cross sectional study was carried out in a medical college of Rawalpindi from September 2014-November 2014. About 400 students were inducted with 77% (n=308) response rate. After taking informed verbal consent from students and administration, a pre-designed and pre-tested questionnaire was circulated among students of third, fourth and final year MBBS as well as third and fourth year BDS. The data collected was entered and analyzed using SPSS 20. Results: The response rate was 77% (308/400). About 244 (79.2%) of students had heard about EVD before. One hundred and sixty four (53.2%) of the students correctly identified that no treatment is available for EVD as yet. Also 163 (52.9%) said that no vaccine was available against the virus either. Washing hands every time after touching a patient in clinics/wards was important for 151 (49.0%) while 223 (72.4%) claimed to use proper techniques to dispose off used injections. Conclusion: Students have basic knowledge regarding EVD. However, there is deficient information regarding the diagnosis and precautionary measures required to control it. PMID:27648059

  14. Substellar Objects in Nearby Young Clusters VII: The substellar mass function revisited

    CERN Document Server

    Scholz, Aleks; Clark, Paul; Jayawardhana, Ray; Muzic, Koraljka

    2013-01-01

    The abundance of brown dwarfs (BDs) in young clusters is a diagnostic of star formation theory. Here we revisit the issue of determining the substellar initial mass function (IMF), based on a comparison between NGC1333 and IC348, two clusters in the Perseus star-forming region. We derive their mass distributions for a range of model isochrones, varying distances, extinction laws and ages, with comprehensive assessments of the uncertainties. We find that the choice of isochrone and other parameters have significant effects on the results, thus we caution against comparing IMFs obtained using different approaches. For NGC1333, we find that the star/BD ratio R is between 1.9 and 2.4, for all plausible scenarios, consistent with our previous work. For IC348, R is between 2.9 and 4.0, suggesting that previous studies have overestimated this value. Thus, the star forming process generates about 2.5-5 substellar objects per 10 stars. The derived star/BD ratios correspond to a slope of the power-law mass function of ...

  15. Expression of Immune-Related Genes of Ducks Infected with Avian Pathogenic Escherichia coli (APEC

    Directory of Open Access Journals (Sweden)

    Rong eLi

    2016-05-01

    Full Text Available Avian pathogenic Escherichia coli (APEC can cause severe disease in ducks, characterized by perihepatitis, pericarditis and airsacculitis. Although the studies of bacteria isolation and methods of detection have been reported, host immune responses to APEC infection remain unclear. In response, we systemically examined the expression of immune-related genes and bacteria distribution in APEC-infected ducks. Results demonstrated that APEC can quickly replicate in the liver, spleen and brain, with the highest bacteria content at 2 day post infection. The expression of Toll-like receptors (TLRs, avian β-defensins (AvBDs and major histocompatibility complex (MHC were tested in the liver, spleen and brain of infected ducks. TLR2, TLR4, TLR5 and TLR15 showed different expression patterns, which indicated that they all responded to APEC infection. The expression of AvBD2 was upregulated in all tested tissues during the 3 days of testing, whereas the expression of AvBD4, AvBD5, AvBD7 and AvBD9 were downregulated, and though MHC-I was upregulated on all test days, MHC-II was dramatically downregulated. Overall, our results suggest that APEC can replicate in various tissues in a short time, and the activation of host immune responses begins at onset of infection. These findings thus clarify duck immune responses to APEC infection and offer insights into its pathogenesis.

  16. Expression of Immune-Related Genes of Ducks Infected with Avian Pathogenic Escherichia coli (APEC).

    Science.gov (United States)

    Li, Rong; Li, Ning; Zhang, Jinzhou; Wang, Yao; Liu, Jiyuan; Cai, Yumei; Chai, Tongjie; Wei, Liangmeng

    2016-01-01

    Avian pathogenic Escherichia coli (APEC) can cause severe disease in ducks, characterized by perihepatitis, pericarditis, and airsacculitis. Although the studies of bacteria isolation and methods of detection have been reported, host immune responses to APEC infection remain unclear. In response, we systemically examined the expression of immune-related genes and bacteria distribution in APEC-infected ducks. Results demonstrated that APEC can quickly replicate in the liver, spleen, and brain, with the highest bacteria content at 2 days post infection. The expression of toll-like receptors (TLRs), avian β-defensins (AvBDs) and major histocompatibility complex (MHC) were tested in the liver, spleen, and brain of infected ducks. TLR2, TLR4, TLR5, and TLR15 showed different expression patterns, which indicated that they all responded to APEC infection. The expression of AvBD2 was upregulated in all tested tissues during the 3 days of testing, whereas the expression of AvBD4, AvBD5, AvBD7, and AvBD9 were downregulated, and though MHC-I was upregulated on all test days, MHC-II was dramatically downregulated. Overall, our results suggest that APEC can replicate in various tissues in a short time, and the activation of host immune responses begins at onset of infection. These findings thus clarify duck immune responses to APEC infection and offer insights into its pathogenesis. PMID:27199963

  17. Application of solid-phase extraction for determination of phenolic compounds in barrique wines.

    Science.gov (United States)

    Matejícek, D; Klejdus, B; Mikes, O; Sterbová, D; Kubán, V

    2003-09-01

    A fast, selective and sensitive chromatographic method has been developed for determination of gallic, protocatechuic, p-hydroxybenzoic, vanillic, caffeic, syringic, p-coumaric, benzoic, ferulic, sinapic, cinnamic, and ellagic acids and p-hydroxybenzaldehyde, vanillin, syringaldehyde, 2-furfural, 5-methylfurfural, and 5-methoxyfurfural. The compounds from untreated wine samples were pre-concentrated and cleaned using solid-phase extraction on RP-105 polymeric sorbent. The cartridge was conditioned with methanol and water. Co-extracted ballast substances were rinsed from the sorbent with 0.1 mol L(-1) hydrochloric acid-methanol, 1:4 (v/ v). Retained phenolic compounds were selectively eluted with diethyl ether. A linear mobile phase gradient containing 0.3% acetic acid and methanol was used for final baseline chromatographic separation on a Hypersil BDS C18 column. Limits of detection (LOD=3 s(bl)) in the range 5.2 to 181.2 microg L(-1), resolution (R) better than 1.7, and repeatability of 2.7-5.1% (RSD for real samples) were achieved. The method was applied for quantification of individual phenolic compounds in barrique wines. PMID:12923605

  18. Non-leptonic decays of $B \\to ( f_1(1285),f_1(1420) ) V$ in the perturbative QCD approach

    CERN Document Server

    Liu, Xin; Zou, Zhi-Tian

    2016-01-01

    We investigate the branching ratios, the polarization fractions, the direct CP-violating asymmetries, and the relative phases in 20 non-leptonic decay modes of $B \\to f_1 V$ within the framework of perturbative QCD approach at leading order with $f_1$ including two $^3\\!P_1$-axial-vector states $f_1(1285)$ and $f_1(1420)$. Here, $B$ denotes $B^+$, $B^0$, and $B_s^0$ mesons and $V$ stands for the lightest vector mesons $\\rho$, $K^*$, $\\omega$, and $\\phi$ , respectively. The $B_s^0 \\to f_1 V$ decays are studied theoretically for the first time in the literature. Together with the angle $\\phi_{f_1} \\approx (24^{+3.2}_{-2.7})^\\circ$ extracted from the measurement through $B_{d/s} \\to J/\\psi f_1(1285)$ modes for the $f_1(1285)-f_1(1420)$ mixing system, it is of great interest to find phenomenologically that some modes such as the tree-dominated $B^+ \\to f_1 \\rho^+$ and the penguin-dominated $B^{+,0} \\to f_1 K^{*+,0}, B_s^0 \\to f_1 \\phi$ with large branching ratios around ${\\cal O}(10^{-6})$ or even ${\\cal O}(10^{-...

  19. 反相高效液相色谱法分析化妆品用白色茶多酚%Analysis of tea leaf white polyphenols used as ingredient in cosmetics by HPLC

    Institute of Scientific and Technical Information of China (English)

    蒋永红; 曹礼群; 李五洲; 马培栋; 王建

    2004-01-01

    采用反相高效液相色谱法测定化妆品用白色茶多酚中的多种活性成分.色谱柱:Hypersil BDS C184.6×200 mm;流动相:梯度洗脱,A相为0.5%HAc水溶液与乙腈体积比为95:5,B相为甲醇与乙腈与0.5%醋酸水溶液体积比为50:30:20;流速为0.8 mL/min;检测波长为280 nm.结果表明:该方法能同时测定儿茶素没食子酸酯、表没食子儿茶素、右旋儿茶素、表没食子儿茶素没食子酸酯、表儿茶素、没食子儿茶素没食子酸酯、表儿茶素没食子酸酯和咖啡因,这8种组分的质量分数与峰面积有良好的线性关系(r=0.998 2~0.999 9),加样回收率为86.9%~106.6%(n=5).

  20. 高效液相色谱法测定酒中的赭曲霉毒素A%Determination of Ochratoxin in wine by liquid chromatography

    Institute of Scientific and Technical Information of China (English)

    许烨; 马荣山; 李军

    2006-01-01

    研究了单克隆免疫亲和柱-高效液相色谱法测定酒中赭曲霉毒素A的方法.脱气后的酒类样品用1%PEG和5%NaHCO3的水溶液稀释,然后通过Ochra Trst免疫亲和柱净化,净化液经Hypersil BDS C18柱反相色谱柱分离、荧光检测器检测、外标法定量.对添加不同含量的赭曲霉毒素A进行6次反复实验,得其平均回收率为92.8%-99.5%,RSD%<10,最低检测限为0.04ng/mL,线性范围为0.1-10ng/mL.

  1. An analytical study on the carrier-phase linear combinations for triple-frequency GNSS

    Science.gov (United States)

    Li, Jinlong; Yang, Yuanxi; He, Haibo; Guo, Hairong

    2016-08-01

    The linear combinations of multi-frequency carrier-phase measurements for Global Navigation Satellite System (GNSS) are greatly beneficial to improving the performance of ambiguity resolution (AR), cycle slip correction as well as precise positioning. In this contribution, the existing definitions of the carrier-phase linear combination are reviewed and the integer property of the resulting ambiguity of the phase linear combinations is examined. The general analytical method for solving the optimal integer linear combinations for all triple-frequency GNSS is presented. Three refined triple-frequency integer combinations solely determined by the frequency values are introduced, which are the ionosphere-free (IF) combination that the Sum of its integer coefficients equal to 0 (IFS0), the geometry-free (GF) combination that the Sum of its integer coefficients equal to 0 (GFS0) and the geometry-free and ionosphere-free (GFIF) combination. Besides, the optimal GF, IF, extra-wide lane and ionosphere-reduced integer combinations for GPS and BDS are solved exhaustively by the presented method. Their potential applications in cycle slip detection, AR as well as precise positioning are discussed. At last, a more straightforward GF and IF AR scheme than the existing method is presented based on the GFIF integer combination.

  2. Correlations in Minimal U(2)^3 models and an SO(10) SUSY GUT model facing new data

    CERN Document Server

    Girrbach, Jennifer

    2012-01-01

    Models with an approximate U(2)^3 flavour symmetry represent simple non-MFV extensions of the SM. We compare correlations of Delta F = 2 observables in CMFV and in a minimal version of U(2)^3 models, MU(2)^3, where only the minimal set of spurions for breaking the symmetry is used and where only SM operators are relevant. Due to the different treatment of the third generation MU(2)^3 models avoid the Delta M_{s,d}-|epsilon_K| correlation of CMFV which precludes to solve the S_{psi K_S}- |epsilon_K| tension present in the flavour data. While the flavour structure in K meson system is the same for CMFV and MU(2)^3 models, CP violation in B_{d,s} system can deviate in MU(2)^3 models from CMFV. We point out a triple correlation between S_{psi phi}, S_{psi K_S} and |V_{ub}| that can provide a distinction between different MU(2)^3 models. GUTs open the possibility to transfer the neutrino mixing matrix U_{PMNS} to the quark sector which leads to correlations between leptonic and hadronic observables. This is accomp...

  3. Observation of two new Ξ(b)(-) baryon resonances.

    Science.gov (United States)

    Aaij, R; Adeva, B; Adinolfi, M; Affolder, A; Ajaltouni, Z; Akar, S; Albrecht, J; Alessio, F; Alexander, M; Ali, S; Alkhazov, G; Alvarez Cartelle, P; Alves, A A; Amato, S; Amerio, S; Amhis, Y; An, L; Anderlini, L; Anderson, J; Andreassen, R; Andreotti, M; Andrews, J E; Appleby, R B; Aquines Gutierrez, O; Archilli, F; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Baalouch, M; Bachmann, S; Back, J J; Badalov, A; Baesso, C; Baldini, W; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Batozskaya, V; Battista, V; Bay, A; Beaucourt, L; Beddow, J; Bedeschi, F; Bediaga, I; Belogurov, S; Belous, K; Belyaev, I; Ben-Haim, E; Bencivenni, G; Benson, S; Benton, J; Berezhnoy, A; Bernet, R; Bertolin, A; Bettler, M-O; van Beuzekom, M; Bien, A; Bifani, S; Bird, T; Bizzeti, A; Bjørnstad, P M; Blake, T; Blanc, F; Blouw, J; Blusk, S; Bocci, V; Bondar, A; Bondar, N; Bonivento, W; Borghi, S; Borgia, A; Borsato, M; Bowcock, T J V; Bowen, E; Bozzi, C; Brett, D; Britsch, M; Britton, T; Brodzicka, J; Brook, N H; Bursche, A; Buytaert, J; Cadeddu, S; Calabrese, R; Calvi, M; Calvo Gomez, M; Campana, P; Campora Perez, D; Capriotti, L; Carbone, A; Carboni, G; Cardinale, R; Cardini, A; Carson, L; Carvalho Akiba, K; Casanova Mohr, R C M; Casse, G; Cassina, L; Castillo Garcia, L; Cattaneo, M; Cauet, Ch; Cenci, R; Charles, M; Charpentier, Ph; Chefdeville, M; Chen, S; Cheung, S-F; Chiapolini, N; Chrzaszcz, M; Cid Vidal, X; Ciezarek, G; Clarke, P E L; Clemencic, M; Cliff, H V; Closier, J; Coco, V; Cogan, J; Cogneras, E; Cogoni, V; Cojocariu, L; Collazuol, G; Collins, P; Comerma-Montells, A; Contu, A; Cook, A; Coombes, M; Coquereau, S; Corti, G; Corvo, M; Counts, I; Couturier, B; Cowan, G A; Craik, D C; Crocombe, A C; Cruz Torres, M; Cunliffe, S; Currie, R; D'Ambrosio, C; Dalseno, J; David, P; David, P N Y; Davis, A; De Bruyn, K; De Capua, S; De Cian, M; De Miranda, J M; De Paula, L; De Silva, W; De Simone, P; Dean, C-T; Decamp, D; Deckenhoff, M; Del Buono, L; Déléage, N; Derkach, D; Deschamps, O; Dettori, F; Dey, B; Di Canto, A; Di Domenico, A; Dijkstra, H; Donleavy, S; Dordei, F; Dorigo, M; Dosil Suárez, A; Dossett, D; Dovbnya, A; Dreimanis, K; Dujany, G; Dupertuis, F; Durante, P; Dzhelyadin, R; Dziurda, A; Dzyuba, A; Easo, S; Egede, U; Egorychev, V; Eidelman, S; Eisenhardt, S; Eitschberger, U; Ekelhof, R; Eklund, L; El Rifai, I; Elsasser, Ch; Ely, S; Esen, S; Evans, H-M; Evans, T; Falabella, A; Färber, C; Farinelli, C; Farley, N; Farry, S; Fay, R; Ferguson, D; Fernandez Albor, V; Ferreira Rodrigues, F; Ferro-Luzzi, M; Filippov, S; Fiore, M; Fiorini, M; Firlej, M; Fitzpatrick, C; Fiutowski, T; Fol, P; Fontana, M; Fontanelli, F; Forty, R; Francisco, O; Frank, M; Frei, C; Frosini, M; Fu, J; Furfaro, E; Gallas Torreira, A; Galli, D; Gallorini, S; Gambetta, S; Gandelman, M; Gandini, P; Gao, Y; García Pardiñas, J; Garofoli, J; Garra Tico, J; Garrido, L; Gascon, D; Gaspar, C; Gastaldi, U; Gauld, R; Gavardi, L; Gazzoni, G; Geraci, A; Gersabeck, E; Gersabeck, M; Gershon, T; Ghez, Ph; Gianelle, A; Gianì, S; Gibson, V; Giubega, L; Gligorov, V V; Göbel, C; Golubkov, D; Golutvin, A; Gomes, A; Gotti, C; Grabalosa Gándara, M; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graverini, E; Graziani, G; Grecu, A; Greening, E; Gregson, S; Griffith, P; Grillo, L; Grünberg, O; Gui, B; Gushchin, E; Guz, Yu; Gys, T; Hadjivasiliou, C; Haefeli, G; Haen, C; Haines, S C; Hall, S; Hamilton, B; Hampson, T; Han, X; Hansmann-Menzemer, S; Harnew, N; Harnew, S T; Harrison, J; He, J; Head, T; Heijne, V; Hennessy, K; Henrard, P; Henry, L; Hernando Morata, J A; van Herwijnen, E; Hess, M; Hicheur, A; Hill, D; Hoballah, M; Hombach, C; Hulsbergen, W; Hussain, N; Hutchcroft, D; Hynds, D; Idzik, M; Ilten, P; Jacobsson, R; Jaeger, A; Jalocha, J; Jans, E; Jaton, P; Jawahery, A; Jing, F; John, M; Johnson, D; Jones, C R; Joram, C; Jost, B; Jurik, N; Kandybei, S; Kanso, W; Karacson, M; Karbach, T M; Karodia, S; Kelsey, M; Kenyon, I R; Ketel, T; Khanji, B; Khurewathanakul, C; Klaver, S; Klimaszewski, K; Kochebina, O; Kolpin, M; Komarov, I; Koopman, R F; Koppenburg, P; Korolev, M; Kravchuk, L; Kreplin, K; Kreps, M; Krocker, G; Krokovny, P; Kruse, F; Kucewicz, W; Kucharczyk, M; Kudryavtsev, V; Kurek, K; Kvaratskheliya, T; La Thi, V N; Lacarrere, D; Lafferty, G; Lai, A; Lambert, D; Lambert, R W; Lanfranchi, G; Langenbruch, C; Langhans, B; Latham, T; Lazzeroni, C; Le Gac, R; van Leerdam, J; Lees, J-P; Lefèvre, R; Leflat, A; Lefrançois, J; Leroy, O; Lesiak, T; Leverington, B; Li, Y; Likhomanenko, T; Liles, M; Lindner, R; Linn, C; Lionetto, F; Liu, B; Lohn, S; Longstaff, I; Lopes, J H; Lowdon, P; Lucchesi, D; Luo, H; Lupato, A; Luppi, E; Lupton, O; Machefert, F; Machikhiliyan, I V; Maciuc, F; Maev, O; Malde, S; Malinin, A; Manca, G; Mancinelli, G; Mapelli, A; Maratas, J; Marchand, J F; Marconi, U; Marin Benito, C; Marino, P; Märki, R; Marks, J; Martellotti, G; Martinelli, M; Martinez Santos, D; Martinez Vidal, F; Martins Tostes, D; Massafferri, A; Matev, R; Mathe, Z; Matteuzzi, C; Mazurov, A; McCann, M; McCarthy, J; McNab, A; McNulty, R; McSkelly, B; Meadows, B; Meier, F; Meissner, M; Merk, M; Milanes, D A; Minard, M-N; Moggi, N; Molina Rodriguez, J; Monteil, S; Morandin, M; Morawski, P; Mordà, A; Morello, M J; Moron, J; Morris, A-B; Mountain, R; Muheim, F; Müller, K; Mussini, M; Muster, B; Naik, P; Nakada, T; Nandakumar, R; Nasteva, I; Needham, M; Neri, N; Neubert, S; Neufeld, N; Neuner, M; Nguyen, A D; Nguyen, T D; Nguyen-Mau, C; Nicol, M; Niess, V; Niet, R; Nikitin, N; Nikodem, T; Novoselov, A; O'Hanlon, D P; Oblakowska-Mucha, A; Obraztsov, V; Ogilvy, S; Okhrimenko, O; Oldeman, R; Onderwater, C J G; Orlandea, M; Otalora Goicochea, J M; Otto, A; Owen, P; Oyanguren, A; Pal, B K; Palano, A; Palombo, F; Palutan, M; Panman, J; Papanestis, A; Pappagallo, M; Pappalardo, L L; Parkes, C; Parkinson, C J; Passaleva, G; Patel, G D; Patel, M; Patrignani, C; Pearce, A; Pellegrino, A; Penso, G; Pepe Altarelli, M; Perazzini, S; Perret, P; Pescatore, L; Pesen, E; Petridis, K; Petrolini, A; Picatoste Olloqui, E; Pietrzyk, B; Pilař, T; Pinci, D; Pistone, A; Playfer, S; Plo Casasus, M; Polci, F; Poluektov, A; Polyakov, I; Polycarpo, E; Popov, A; Popov, D; Popovici, B; Potterat, C; Price, E; Price, J D; Prisciandaro, J; Pritchard, A; Prouve, C; Pugatch, V; Puig Navarro, A; Punzi, G; Qian, W; Rachwal, B; Rademacker, J H; Rakotomiaramanana, B; Rama, M; Rangel, M S; Raniuk, I; Rauschmayr, N; Raven, G; Redi, F; Reichert, S; Reid, M M; dos Reis, A C; Ricciardi, S; Richards, S; Rihl, M; Rinnert, K; Rives Molina, V; Robbe, P; Rodrigues, A B; Rodrigues, E; Rodriguez Perez, P; Roiser, S; Romanovsky, V; Romero Vidal, A; Rotondo, M; Rouvinet, J; Ruf, T; Ruiz, H; Ruiz Valls, P; Saborido Silva, J J; Sagidova, N; Sail, P; Saitta, B; Salustino Guimaraes, V; Sanchez Mayordomo, C; Sanmartin Sedes, B; Santacesaria, R; Santamarina Rios, C; Santovetti, E; Sarti, A; Satriano, C; Satta, A; Saunders, D M; Savrina, D; Schiller, M; Schindler, H; Schlupp, M; Schmelling, M; Schmidt, B; Schneider, O; Schopper, A; Schune, M-H; Schwemmer, R; Sciascia, B; Sciubba, A; Semennikov, A; Sepp, I; Serra, N; Serrano, J; Sestini, L; Seyfert, P; Shapkin, M; Shapoval, I; Shcheglov, Y; Shears, T; Shekhtman, L; Shevchenko, V; Shires, A; Silva Coutinho, R; Simi, G; Sirendi, M; Skidmore, N; Skillicorn, I; Skwarnicki, T; Smith, N A; Smith, E; Smith, E; Smith, J; Smith, M; Snoek, H; Sokoloff, M D; Soler, F J P; Soomro, F; Souza, D; Souza De Paula, B; Spaan, B; Spradlin, P; Sridharan, S; Stagni, F; Stahl, M; Stahl, S; Steinkamp, O; Stenyakin, O; Sterpka, F; Stevenson, S; Stoica, S; Stone, S; Storaci, B; Stracka, S; Straticiuc, M; Straumann, U; Stroili, R; Sun, L; Sutcliffe, W; Swientek, K; Swientek, S; Syropoulos, V; Szczekowski, M; Szczypka, P; Szumlak, T; T'Jampens, S; Teklishyn, M; Tellarini, G; Teubert, F; Thomas, C; Thomas, E; van Tilburg, J; Tisserand, V; Tobin, M; Todd, J; Tolk, S; Tomassetti, L; Tonelli, D; Topp-Joergensen, S; Torr, N; Tournefier, E; Tourneur, S; Tran, M T; Tresch, M; Trisovic, A; Tsaregorodtsev, A; Tsopelas, P; Tuning, N; Ubeda Garcia, M; Ukleja, A; Ustyuzhanin, A; Uwer, U; Vacca, C; Vagnoni, V; Valenti, G; Vallier, A; Vazquez Gomez, R; Vazquez Regueiro, P; Vázquez Sierra, C; Vecchi, S; Velthuis, J J; Veltri, M; Veneziano, G; Vesterinen, M; Viana Barbosa, J V V B; Viaud, B; Vieira, D; Vieites Diaz, M; Vilasis-Cardona, X; Vollhardt, A; Volyanskyy, D; Voong, D; Vorobyev, A; Vorobyev, V; Voss, C; de Vries, J A; Waldi, R; Wallace, C; Wallace, R; Walsh, J; Wandernoth, S; Wang, J; Ward, D R; Watson, N K; Websdale, D; Whitehead, M; Wiedner, D; Wilkinson, G; Wilkinson, M; Williams, M P; Williams, M; Wilschut, H W; Wilson, F F; Wimberley, J; Wishahi, J; Wislicki, W; Witek, M; Wormser, G; Wotton, S A; Wright, S; Wyllie, K; Xie, Y; Xing, Z; Xu, Z; Yang, Z; Yuan, X; Yushchenko, O; Zangoli, M; Zavertyaev, M; Zhang, L; Zhang, W C; Zhang, Y; Zhelezov, A; Zhokhov, A; Zhong, L

    2015-02-13

    Two structures are observed close to the kinematic threshold in the Ξ(b)(0)π(-) mass spectrum in a sample of proton-proton collision data, corresponding to an integrated luminosity of 3.0  fb(-1), recorded by the LHCb experiment. In the quark model, two baryonic resonances with quark content bds are expected in this mass region: the spin-parity J(P)=(1/2)(+) and J(P)=(3/2)(+) states, denoted Ξ(b)('-) and Ξ(b)(*-). Interpreting the structures as these resonances, we measure the mass differences and the width of the heavier state to be m(Ξ(b)('-))-m(Ξ(b)(0))-m(π(-))=3.653±0.018±0.006  MeV/c(2), m(Ξ(b)(*-))-m(Ξ(b)(0))-m(π(-))=23.96±0.12±0.06  MeV/c(2), Γ(Ξ(b)(*-))=1.65±0.31±0.10  MeV, where the first and second uncertainties are statistical and systematic, respectively. The width of the lighter state is consistent with zero, and we place an upper limit of Γ(Ξ(b)('-))<0.08  MeV at 95% confidence level. Relative production rates of these states are also reported. PMID:25723210

  4. Interaction Energy Calculations of Edge Dislocation with Point Defects in FCC Cu

    International Nuclear Information System (INIS)

    Swelling has always been a limitation for long term operating reactors. The simple Bias model has done a good job in describing swelling in electron irradiation. In order to apply it to neutron irradiation, there's the key parameter named Bias Factor (Bd), which plays an important role in the model, has to be figured out. However, the Bds fitted from experiments are not consistent with those derived from elasticity theory. The major problem lies on the fact that analytical interactions based on elasticity theory are not valid around the dislocation core region. Hence a careful work about the interaction energy map is required in order to have numerical solution of Bd. In the present work, we apply large scale of atomistic calculations with EAM potential to get the interaction energy map between Point Defects (Vacancy and dumbbell SIAs along <100> directions) and dislocation in FCC Cu, as a demonstration of general FCC based material. General properties are checked in atomistic calculation results; Comparison has been made between the elasticity results and the atomistic results. The atomistic calculation of interaction maps show reasonable profiles. And they give better description around the dislocation core region. (author)

  5. Development and validation of a reversed-phase HPLC method for separation and simultaneous determination of process-related substances of mirtazapine in bulk drugs and formulations.

    Science.gov (United States)

    Rao, R Nageswara; Raju, A Narasa

    2009-03-01

    A simple and rapid reversed-phase high-performance liquid chromatographic method has been developed for the separation and simultaneous determination of related substances of mirtazapine in bulk drugs and pharmaceutical formulations. Six impurities, including one degradation product of mirtazapine, have been separated on a BDS Hypersil (4.6 x 250 mm; particle size 5 microm) column with a mobile phase consisting of 0.3% triethylamine (pH 3.0)-acetonitrile (78:22 v/v) eluted in an isocratic mode and monitored with a photo diode array detector at 215 nm. The chromatographic behavior of all the analytes was studied under variable compositions of different solvent systems, temperatures, buffer concentrations, and pH values. The method was validated in terms of accuracy, precision, and linearity. The inter- and intra-day assay precision was found to be method was successfully applied to the analysis of commercial formulations and the recoveries of mirtazapine were in the range of 99.38-100.73% with method is useful not only for rapid evaluation of the purity of mirtazapine, but also for the simultaneous determination of related substances in bulk drugs and pharmaceutical formulations.

  6. Determination of 2-Naphthylamine-6-Sulfomethylamide and Its Impurities by High Performance Liquid Chromatography%高效液相色谱法测定2-氨基萘-6-磺酰甲胺及其杂质

    Institute of Scientific and Technical Information of China (English)

    李俊; 胡泉源; 周彩霞; 胡先明

    2000-01-01

    研究了一种同时测定2-氨基萘-6-磺酰甲胺及其杂质(2-氨基萘,2-乙酰氨基萘-6-磺酸,2-氨基萘-6-磺酸和2-乙酰氨基萘-6-磺酰甲胺)含量的高效液相色谱法.采用HypersilBDS C18色谱柱,0.2%四丁基铵高氯酸盐(TBAPC)/乙腈/36%乙酸(60:38:2,V/V/V)为流动相,柱温30℃,在流速为1 mL/min时,上述5种物质在20 min内实现了基线分离.本方法快速、准确,适用于2-氨基萘-6-磺酰甲胺生产的在线监控以及产品质量监督.

  7. NASA Bioreactor Demonstration System

    Science.gov (United States)

    2002-01-01

    Leland W. K. Chung (left), Director, Molecular Urology Therapeutics Program at the Winship Cancer Institute at Emory University, is principal investigator for the NASA bioreactor demonstration system (BDS-05). With him is Dr. Jun Shu, an assistant professor of Orthopedics Surgery from Kuming Medical University China. The NASA Bioreactor provides a low turbulence culture environment which promotes the formation of large, three-dimensional cell clusters. Due to their high level of cellular organization and specialization, samples constructed in the bioreactor more closely resemble the original tumor or tissue found in the body. The Bioreactor is rotated to provide gentle mixing of fresh and spent nutrient without inducing shear forces that would damage the cells. The work is sponsored by NASA's Office of Biological and Physical Research. The bioreactor is managed by the Biotechnology Cell Science Program at NASA's Johnson Space Center (JSC). NASA-sponsored bioreactor research has been instrumental in helping scientists to better understand normal and cancerous tissue development. In cooperation with the medical community, the bioreactor design is being used to prepare better models of human colon, prostate, breast and ovarian tumors. Cartilage, bone marrow, heart muscle, skeletal muscle, pancreatic islet cells, liver and kidney are just a few of the normal tissues being cultured in rotating bioreactors by investigators. Credit: Emory University.

  8. Preconcentration and determination of chlordiazepoxide and diazepam drugs using dispersive nanomaterial-ultrasound assisted microextraction method followed by high performance liquid chromatography.

    Science.gov (United States)

    Pebdani, A Amiri; Khodadoust, S; Talebianpoor, M S; Zargar, H R; Zarezade, V

    2016-01-01

    Benzodiazepines (BDs) are used widely in clinical practice, due to their multiple pharmacological functions. In this study a dispersive nanomaterial-ultrasound assisted- microextraction (DNUM) method followed by high performance liquid chromatography (HPLC) was used for the preconcentration and determination of chlordiazepoxide and diazepam drugs from urine and plasma samples. Various parameters such as amount of adsorbent (mg: ZnS-AC), pH and ionic strength of sample solution, vortex and ultrasonic time (min), and desorption volume (mL) were investigated by fractional factorial design (FFD) and central composite design (CCD). Regression models and desirability functions (DF) were applied to find the best experimental conditions for providing the maximum extraction recovery (ER). Under the optimal conditions a linear calibration curve were obtained in the range of 0.005-10μgmL(-1) and 0.006-10μgmL(-1) for chlordiazepoxide and diazepam, respectively. To demonstrate the analytical performance, figures of merits of the proposed method in urine and plasma spiked with chlordiazepoxide and diazepam were investigated. The limits of detection of chlordiazepoxide and diazepam in urine and plasma were ranged from 0.0012 to 0.0015μgmL(-1), respectively.

  9. Preconcentration and determination of chlordiazepoxide and diazepam drugs using dispersive nanomaterial-ultrasound assisted microextraction method followed by high performance liquid chromatography.

    Science.gov (United States)

    Pebdani, A Amiri; Khodadoust, S; Talebianpoor, M S; Zargar, H R; Zarezade, V

    2016-01-01

    Benzodiazepines (BDs) are used widely in clinical practice, due to their multiple pharmacological functions. In this study a dispersive nanomaterial-ultrasound assisted- microextraction (DNUM) method followed by high performance liquid chromatography (HPLC) was used for the preconcentration and determination of chlordiazepoxide and diazepam drugs from urine and plasma samples. Various parameters such as amount of adsorbent (mg: ZnS-AC), pH and ionic strength of sample solution, vortex and ultrasonic time (min), and desorption volume (mL) were investigated by fractional factorial design (FFD) and central composite design (CCD). Regression models and desirability functions (DF) were applied to find the best experimental conditions for providing the maximum extraction recovery (ER). Under the optimal conditions a linear calibration curve were obtained in the range of 0.005-10μgmL(-1) and 0.006-10μgmL(-1) for chlordiazepoxide and diazepam, respectively. To demonstrate the analytical performance, figures of merits of the proposed method in urine and plasma spiked with chlordiazepoxide and diazepam were investigated. The limits of detection of chlordiazepoxide and diazepam in urine and plasma were ranged from 0.0012 to 0.0015μgmL(-1), respectively. PMID:26655106

  10. Detect ground motion effects on the trajectory at ATF2

    CERN Document Server

    Rénier, Yves; Garcia, Rogelio

    2011-01-01

    The Accelerator Test Facility 2 (ATF2) commissioning group aims to demonstrate the feasibility of the Beam Delivery System (BDS) of the next linear colliders (ILC and CLIC) as well as to define and to test the tunning methods. As the design vertical beam sizes of the linear colliders are about few nanometers, the stability of the trajectory as well as the control of the aberrations are very critical. The magnet displacements induced by ground motion are large enough for CLIC to perturb the beam stability above requirements. It is planned to measure the displacement of the magnets and implement a feed-forward correcting the effects on the beam trajectory with correctors (dipoles). This article studies the possibility to detect ground motion effects on the beam trajectory at ATF2. Characteristics of the ground motion at ATF2 are presented, the effects of the magnet displacements on the beam trajectory are simulated and an algorithm predicting the induced trajectory fluctuations is evaluated. After the estimated...

  11. Development and validation of an HPLC method for analysis of etoricoxib in human plasma

    Directory of Open Access Journals (Sweden)

    Mandal U

    2006-01-01

    Full Text Available A simple high-performance liquid chromatographic method for the determination of etoricoxib in human plasma has been developed. An aliquot quantity of 1 ml plasma sample was taken and 10 ml internal standard was added and mixed. Saturated borate solution of 0.3 ml was added to it and mixed for 1 minute followed by liquid-liquid extraction with ethyl acetate. Organic layer was separated and evaporated to dryness under nitrogen atmosphere at low temperature (below 50°. Residue was reconstituted with 150 µl of mobile phase. During the whole procedure the samples were protected from light. The assay was performed on Hypersil BDS, C18 (150x4.6 mm, 5 m particle size column, using 10 milimol ammonium acetate buffer:acetonitrile = 65:35 v/v as mobile phase with ultra violet detection at 235 nm. Lower limit of detection was 10 ng/ml and lower limit of quantitation was 20 ng/ml. Maximum between-run precision was 7.94%. Mean extraction recovery was found to be 79.53 to 85.70%. Stability study showed that after three freeze-thaw cycles the loss of three quality control samples were less than 10%. Samples were stable at room temperature for 12 h and at -20° for 3 months. Before injecting onto HPLC system, the processed samples were stable for at least 8 h. The method was used to perform bioequivalence study in human.

  12. Discharge expansion in barrier discharge arrangements at low applied voltages

    International Nuclear Information System (INIS)

    This study evaluates the spatial expansion of barrier discharges (BDs) in oxygen, carbon dioxide, synthetic air, and helium at atmospheric pressure. Despite being confined in narrow gas channels, the BD plasma only partially covers the available discharge area at low applied voltages as was experimentally observed. This is important for homogeneous surface treatment. The appearance of local discharge zones in the plasma development results in a variation of the capacitive behaviour of the equivalent electric circuit as a function of the applied voltage. This transient behaviour of the apparent dielectric capacitance is therefore investigated for various discharge areas and different gas compositions. Furthermore, a semi-empirical model describing the expansion behaviour is proposed and validated by means of the obtained experimental data. The results clearly show that a three times higher voltage excess is required for oxygen-containing gases compared with helium in order to develop full plasma expansion. For the discharge areas considered, the size of the available electrode plays a minor role in the plasma expansion process.

  13. Studies on HPLC fingerprint of Ultramicro Radix scutellariae%黄芩超微饮片的HPLC指纹图谱研究

    Institute of Scientific and Technical Information of China (English)

    蔡光先; 王实强; 谢谊

    2005-01-01

    为了研究黄芩超微饮片的指纹图谱,采用色谱柱为大连依利特公司Hypersil BDS C18(4.6 mm×200 mm,5μm).流动相为甲醇-0.1%磷酸水溶液(45:55),柱温为25℃,流速为1.0mL·min-1,检测波长为280 nm,进样量为10μL.结果初步建立了黄芩超微饮片的HPLC指纹图谱,标定了6个共有指纹峰.结果表明,利用黄芩超微饮片HPLC指纹图谱可以较好地反映黄芩超微饮片的内在质量.

  14. Study on HPLC Fingerprint of Ultrafine Radix Scutellariae%黄芩超微饮片的HPLC指纹图谱研究

    Institute of Scientific and Technical Information of China (English)

    蔡光先; 王实强; 谢谊

    2005-01-01

    为了研究黄芩超微饮片的指纹图谱.采用色谱柱为大连依利特公司产品Hypersil BDS C18(4.6 mm×200 mm,5μm).流动相为甲醇-0.1%磷酸水溶液(45:55),柱温为25℃,流速为1.0 mL·min-1,检测波长为280 nm,进样量为10μL.初步建立了黄芩超微饮片的HPLC指纹图谱,标定了6个共有指纹峰.研究表明,利用黄芩超微饮片HPLC指纹图谱可以较好地反映黄芩超微饮片的内在质量.

  15. Redirected charge transport arising from diazonium grafting of carbon coated LiFePO4.

    Science.gov (United States)

    Madec, L; Seid, K A; Badot, J-C; Humbert, B; Moreau, P; Dubrunfaut, O; Lestriez, B; Guyomard, D; Gaubicher, J

    2014-11-01

    The morphological and the electrical properties of carbon coated LiFePO4 (LFPC) active material functionalized by 4-ethynylbenzene tetrafluoroboratediazonium salt were investigated. For this purpose, FTIR, Raman, XPS, High Resolution Transmission Electron Microscopy (HRTEM) and Broadband Dielectric Spectroscopy (BDS) were considered. Electronic conductivities of LFPC samples at room temperature were found to decrease in a large frequency range upon simple immersion in polar solvents and to decrease further upon functionalization. Due to their high dipole moment, strongly physisorbed molecules detected by XPS likely add barriers to electron hopping. Significant alteration of the carbon coating conductivity was only observed, however, upon functionalization. This effect is most presumably associated with an increase in the sp(3) content determined by Raman spectroscopy, which is a strong indication of the formation of a covalent bond between the organic layer and the carbon coating. In this case, the electron flux appears to be redirected and relayed by short-range (intra chain) and long-range (inter chain) electron transport through molecular oligomers anchored at the LFPC surface. The latter are controlled by tunnelling and slightly activated hopping, which enable higher conductivity at low temperature (T LiFePO4. XPS and HRTEM images allow a clear correlation of these findings with the island type oligomeric structure of grafted molecules. PMID:25234701

  16. Comparison of Active Ingredient Content of Nanwuweizi and Beiwuweizi Collected in Different Seasons Detected by HPLC-DAD

    Institute of Scientific and Technical Information of China (English)

    YAO Feng; CHEN Da-shuai

    2015-01-01

    Objective:To compare the active ingredient content of Nanwuweizi (Kadsura longepedunculata) and Beiwuweizi (Fructus Schisandrae Chinensis) collected in different seasons. Methods:Microwave-assisted extraction was applied to extract the active ingredients in Nanwuweizi and Beiwuweizi, with methanol as the solvent. High performance liquid chromatography-diode array detection (HPLC-DAD) method was used to analyze the content of each ingredient, with chromatographic conditions as follows: Brava BDS C18 column (250 mm×4.6 mm, 5 μm); column temperature: 30℃; mobile phase: water (A) - acetonitrile (B); gradient elution: 0.8 mL/min; and detection wavelength: 225 nm. Results:All ingredients waiting for detection reached their peaks within 75 min, with excellent degree of separation and higher number of theoretical plates. Standard curves were drawn, and the mean value of phase relationship of each ingredient was >0.999. The content of active ingredients in lignans of Nanwuweizi and Beiwuweizi showed tendency of increase ifrst and then decreased. In addition, all ingredients in Beiwuweizi reached their peaks in September while those in Nanwuweizi in August. Conclusion:This method can be used to detect the content of multiple ingredients in Wuweizi (Schisandra chinensis) simultaneously because it is simple in operation, precise in results and excellent in repeatability.

  17. Methodological Establishment of HPLC-DAD for Determination of 10 Active Ingredients in Wuweizi

    Directory of Open Access Journals (Sweden)

    Feng YAO

    2015-09-01

    Full Text Available Objective: To establish high performance liquid chromatography-diode array detection (HPLC-DAD method for the determination of active ingredients of multiple lignans in Nanwuweizi (Kadsura longepedunculata and Beiwuweizi (Fructus Schisandrae Chinensis so as to set up the standard for the quality control of Wuweizi (Schisandra chinensis. Methods: Brava BDS C18 column (250 mm×4.6 mm, 5 μm was applied, with detection condition as follows: column temperature: 30℃; mobile phase: water (A-acetonitrile (B; gradient elution: 0.8 mL/min and detection wavelength: 225 nm.Results: Ten ingredients in Beiwuweizi and 5 in Nanwuweizi were completely separately within 75 min. Peak area was in favorable linear relationship with concentration. In addition, the recovery rate was 96.87-103.29% and relative standard deviation (RSD was 0.68-2.09%.Conclusion: HPLC-DAD is simple and reliable with favorable repeatability, so it can be used for the determination of multiple lignans in Wuweizi.

  18. Methodological Establishment of HPLC-DAD for Determination of 10 Active Ingredients in Wuweizi

    Institute of Scientific and Technical Information of China (English)

    YAO Feng; CHEN Da-shuai

    2015-01-01

    Objective: To establish high performance liquid chromatography-diode array detection (HPLC-DAD) method for the determination of active ingredients of multiple lignans in Nanwuweizi (Kadsura longepedunculata) and Beiwuweizi (Fructus Schisandrae Chinensis) so as to set up the standard for the quality control of Wuweizi (Schisandra chinensis). Methods: Brava BDS C18 column (250 mm×4.6 mm, 5 μm) was applied, with detection condition as follows: column temperature: 30℃; mobile phase: water (A)-acetonitrile (B); gradient elution: 0.8 mL/min and detection wavelength: 225 nm. Results: Ten ingredients in Beiwuweizi and 5 in Nanwuweizi were completely separately within 75 min. Peak area was in favorable linear relationship with concentration. In addition, the recovery rate was 96.87%-103.29% and relative standard deviation (RSD) was 0.68%-2.09%. Conclusion: HPLC-DAD is simple and reliable with favorable repeatability, so it can be used for the determination of multiple lignans in Wuweizi.

  19. Comparison of Active Ingredient Content of Nanwuweizi and Beiwuweizi Collected in Different Seasons Detected by HPLC-DAD

    Directory of Open Access Journals (Sweden)

    Feng YAO

    2015-12-01

    Full Text Available Abstract Objective: To compare the active ingredient content of Nanwuweizi (Kadsura longepedunculata and Beiwuweizi (Fructus Schisandrae Chinensis collected in different seasons. Methods: Microwave-assisted extraction was applied to extract the active ingredients in Nanwuweizi and Beiwuweizi, with methanol as the solvent. High performance liquid chromatography-diode array detection ℃; mobile phase: water (A - acetonitrile (B; gradient elution: 0.8 mL/min; and detection wavelength: 225 nm. (HPLC-DAD method was used to analyze the content of each ingredient, with chromatographic conditions as follows: Brava BDS C18 column (250 mm×4.6 mm, 5 μm; column temperature: 30 Results: All ingredients waiting for detection reached their peaks within 75 min, with excellent degree of separation and higher number of theoretical plates. Standard curves were drawn, and the mean value of phase relationship of each ingredient was >0.999. The content of active ingredients in lignans of Nanwuweizi and Beiwuweizi showed tendency of increase first and then decreased. In addition, all ingredients in Beiwuweizi reached their peaks in September while those in Nanwuweizi in August. Conclusion: This method can be used to detect the content of multiple ingredients in Wuweizi (Schisandra chinensis simultaneously because it is simple in operation, precise in results and excellent in repeatability.

  20. Testing the efficiency market hypothesis for the Colombian stock market

    Directory of Open Access Journals (Sweden)

    Juan Benjamín Duarte-Duarte

    2014-01-01

    Full Text Available Uno de los supuestos básicos de los modelos de valoración de activos (CAPM y APT, es la eficiencia de los mercados. El presente trabajo busca comprobar este requisito en su forma débil, tanto al Índice General de la Bolsa de Valores de Colombia como a las acciones más representativas del mercado colombiano. Para tal fin se comprueba por diferentes métodos estadísticos que las series bursátiles no siguen el patrón de una distribución normal. Además, al indagar sobre la eficiencia del mercado colombiano, mediante los test de Rachas, BDS, LB y Bartlett, se evidencia no aleatoriedad en los principales activos financieros con excepción de Ecopetrol, mientras que para el IGBC se observa una mejora en la eficiencia del mercado del 2008 a 2010, periodo que coincide con el inicio de la crisis económica mundial.