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Sample records for bk020014 pall bds

  1. Precise Positioning of BDS, BDS/GPS: Implications for Tsunami Early Warning in South China Sea

    Directory of Open Access Journals (Sweden)

    Kejie Chen

    2015-11-01

    Full Text Available Global Positioning System (GPS has been proved to be a powerful tool for measuring co-seismic ground displacements with an application to seismic source inversion. Whereas most of the tsunamis are triggered by large earthquakes, GPS can contribute to the tsunami early warning system (TEWS by helping to obtain tsunami source parameters in near real-time. Toward the end of 2012, the second phase of the BeiDou Navigation Satellite System (BDS constellation was accomplished, and BDS has been providing regional positioning service since then. Numerical results indicate that precision of BDS nowadays is equivalent to that of the GPS. Compared with a single Global Satellite Navigation System (GNSS, combined BDS/GPS real-time processing can improve accuracy and especially reliability of retrieved co-seismic displacements. In the present study, we investigate the potential of BDS to serve for the early warning system of tsunamis in the South China Sea region. To facilitate early warnings of tsunamis and forecasting capabilities in this region, we propose to distribute an array of BDS-stations along the Luzon Island (Philippines. By simulating an earthquake with Mw = 8 at the Manila trench as an example, we demonstrate that such an array will be able to detect earthquake parameters in real time with a high degree of accuracy and, hence, contribute to the fast and reliable tsunami early warning system in this region.

  2. Measurement of B(Ds -> munu)

    CERN Document Server

    Abe, K; Aihara, H; Arinstein, K; Aso, T; Aulchenko, V; Aushev, T; Aziz, T; Bahinipati, S; Bakich, A M; Balagura, V; Ban, Y; Banerjee, S; Barberio, E; Bay, A; Bedny, I; Belous, K S; Bhardwaj, V; Bitenc, U; Blyth, S; Bondar, A; Bozek, A; Bracko, M; Brodzicka, J; Browder, T E; Chang, M C; Chang, P; Chao, Y; Chen, A; Chen, K F; Chen, W T; Cheon, B G; Chiang, C C; Chistov, R; Cho, I S; Choi, S K; Choi, Y; Choi, Y K; Cole, S; Dalseno, J; Danilov, M; Das, A; Dash, M; Dragic, J; Drutskoy, A; Eidelman, S; Epifanov, D; Fratina, S; Fujii, H; Fujikawa, M; Gabyshev, N; Garmash, A; Go, A; Gokhroo, G; Goldenzweig, P; Golob, B; Grosse-Perdekamp, M; Guler, H; Ha, H; Haba, J; Hara, K; Hara, T; Hasegawa, Y; Hastings, N C; Hayasaka, K; Hayashii, H; Hazumi, M; Heffernan, D; Higuchi, T; Hinz, L; Hoedlmoser, H; Hokuue, T; Horii, Y; Hoshi, Y; Hoshina, K; Hou, S; Hou, W S; Hsiung, Y B; Hyun, H J; Igarashi, Y; Iijima, T; Ikado, K; Inami, K; Ishikawa, A; Ishino, H; Itoh, R; Iwabuchi, M; Iwasaki, M; Iwasaki, Y; Jacoby, C; Joshi, N J; Kaga, M; Kah, D H; Kaji, H; Kajiwara, S; Kakuno, H; Kang, J H; Kapusta, P; Kataoka, S U; Katayama, N; Kawai, H; Kawasaki, T; Kibayashi, A; Kichimi, H; Kim, H J; Kim, H O; Kim, J H; Kim, S K; Kim, Y J; Kinoshita, K; Korpar, S; Kozakai, Y; Krizan, P; Krokovny, P; Kumar, R; Kurihara, E; Kusaka, A; Kuzmin, A; Kwon, Y J; Lange, J S; Leder, G; Lee, J; Lee, J S; Lee, M J; Lee, S E; Lesiak, T; Li, J; Limosani, A; Lin, S W; Liu, Y; Liventsev, D; MacNaughton, J; Majumder, G; Mandl, F; Marlow, D; Matsumura, T; Matyja, A; McOnie, S; Medvedeva, T; Mikami, Y; Mitaroff, W A; Miyabayashi, K; Miyake, H; Miyata, H; Miyazaki, Y; Mizuk, R; Moloney, G R; Mori, T; Müller, J; Murakami, A; Nagamine, T; Nagasaka, Y; Nakahama, Y; Nakamura, I; Nakano, E; Nakao, M; Nakayama, H; Nakazawa, H; Natkaniec, Z; Neichi, K; Nishida, S; Nishimura, K; Nishio, Y; Nishizawa, I; Nitoh, O; Noguchi, S; Nozaki, T; Ogawa, A; Ogawa, S; Ohshima, T; Okuno, S; Olsen, S L; Ono, S; Ostrowicz, W; Ozaki, H; Pakhlov, P; Pakhlova, G; Palka, H; Park, C W; Park, H; Park, K S; Parslow, N; Peak, L S; Pernicka, M; Pestotnik, R; Peters, M; Piilonen, L E; Poluektov, A; Rorie, J; Rózanska, M; Sahoo, H; Sakai, Y; Sakaue, H; Sasao, N; Sarangi, T R; Satoyama, N; Sayeed, K; Schietinger, T; Schneider, O; Schonmeier, P; Schümann, J; Schwanda, C; Schwartz, A J; Seidl, R; Sekiya, A; Senyo, K; Sevior, M E; Shang, L; Shapkin, M; Shen, C P; Shibuya, H; Shinomiya, S; Shiu, J G; Shwartz, B; Singh, J B; Sokolov, A; Solovieva, E; Somov, A; Stanic, S; Staric, M; Stypula, J; Sugiyama, A; Sumisawa, K; Sumiyoshi, T; Suzuki, S; Suzuki, S Y; Tajima, O; Takasaki, F; Tamai, K; Tamura, N; Tanaka, M; Taniguchi, N; Taylor, G N; Teramoto, Y; Tikhomirov, I; Trabelsi, K; Tse, Y F; Tsuboyama, T; Uchida, K; Uchida, Y; Uehara, S; Ueno, K; Uglov, T; Unno, Y; Uno, S; Urquijo, P; Ushiroda, Y; Usov, Yu; Varner, G; Varvell, K E; Vervink, K; Villa, S; Vinokurova, A; Wang, C C; Wang, C H; Wang, J; Wang, M Z; Wang, P; Wang, X L; Watanabe, M; Watanabe, Y; Wedd, R; Wicht, J; Widhalm, L; Wiechczynski, J; Won, E; Yabsley, B D; Yamaguchi, A; Yamamoto, H; Yamaoka, M; Yamashita, Y; Yamauchi, M; Yuan, C Z; Yusa, Y; Zhang, C C; Zhang, L M; Zhang, Z P; Zhilich, V; Zhulanov, V; Zupanc, A; Zwahlen, N

    2007-01-01

    We present preliminary results for the branching fraction B(Ds -> munu) using a 548 fb^-1 data sample collected by the Belle experiment at the KEKB e+e- collider. The Ds momentum is determined by full reconstruction of the recoil system in events of the type e+e- -> D*sDKX, D*s -> Ds gamma where X is any number of additional pions or photons from fragmentation. The full reconstruction method provides high resolution in the neutrino momentum and thus good background separation, equivalent to that reached at experiments at the tau-charm factories such as CLEO-c or BES. We obtain the preliminary branching fraction B(Ds -> munu) = (6.44 +- 0.76 (stat) +- 0.52 (syst)) x 10^(-3), implying a Ds decay constant of f_Ds = 275 +- 16 (stat) +- 12 (syst) MeV.

  3. The ISS Sensitizing Agents Data Bank (BDS)

    International Nuclear Information System (INIS)

    The Istituto Superiore Sanita has developed a data bank on sensitizing substances (Banca Dati Sensibilizzanti, BDS), available on website (www.iss.it/bdse/), sharing complete, controlled and updated information coming from different sources, such as scientific publications, international agencies and governmental or non governmental organizations. It is worthwhile that the main objective of the BDS is not the classification of sensitizing or potentially sensitizing agents within specific risk classes, but it is essentially to provide concise and non confidential information related to this endpoint. At present, the BDS includes: all the substances officially classified by European Union, (Annex I to Directive 67/548/EEC), some substances listed in Annex I (Directive 67/548/EEC) for endpoints different than sensitization but indicated as sensitizers by other relevant institutions, all the substances indicated as sensitizers by relevant agencies or institutions (AC GIH, DFG), some substances indicated as sensitizers by industry and other non-governmental organizations (ETA D and HERA), all the substances regarded as potentially sensitizing dyes by the Commission of the European Community for the award of the Community eco-label to textile products, some substances for which, even in the absence of any categorization by European Union, AC GIH or DFG, it is not possible to exclude a sensitizing potential on the basis of reliable documents

  4. The PPP Precision Analysis Based on BDS Regional Navigation System

    Directory of Open Access Journals (Sweden)

    ZHU Yongxing

    2015-04-01

    Full Text Available BeiDou navigation satellite system(BDS has opened service in most of the Asia-Pacific region, it offers the possibility to break the technological monopoly of GPS in the field of high-precision applications, so its performance of precise point positioning (PPP has been a great concern. Firstly, the constellation of BeiDou regional navigation system and BDS/GPS tracking network is introduced. Secondly, the precise ephemeris and clock offset accuracy of BeiDou satellite based on domestic tracking network is analyzed. Finally, the static and kinematic PPP accuracy is studied, and compared with the GPS. The actual measured numerical example shows that the static and kinematic PPP based on BDS can achieve centimeter-level and decimeter-level respectively, reaching the current level of GPS precise point positioning.

  5. The PPP Precision Analysis Based on BDS Regional Navigation System

    OpenAIRE

    Zhu, Yongxing; FENG Laiping; Jia, Xiaolin; Zhang, Qinghua; RUAN Rengui

    2015-01-01

    BeiDou navigation satellite system(BDS) has opened service in most of the Asia-Pacific region, it offers the possibility to break the technological monopoly of GPS in the field of high-precision applications, so its performance of precise point positioning (PPP) has been a great concern. Firstly, the constellation of BeiDou regional navigation system and BDS/GPS tracking network is introduced. Secondly, the precise ephemeris and clock offset accuracy of BeiDou satellite based on domestic trac...

  6. Mapping continental-scale biomass burning and smoke palls from the space shuttle

    Science.gov (United States)

    Lulla, Kamlesh; Helfert, Michael

    1992-01-01

    Space shuttle photographs have been used to map the areal extent of Amazonian smoke palls associated with biomass burning. Areas covered with smoke have increased from approximately 300,000 sq km to continental-size smoke palls of approximately 3,000,000 sq km. The smoke palls interpreted from the STS-48 data indicate that this phenomenon is persistent. Astronaut observations of such dynamic and vital environmental phenomena indicate the possibility of intergrating the earth observation capabilities of all space platforms in future modeling of the earth's dynamic processes.

  7. An enhanced algorithm to estimate BDS satellite's differential code biases

    Science.gov (United States)

    Shi, Chuang; Fan, Lei; Li, Min; Liu, Zhizhao; Gu, Shengfeng; Zhong, Shiming; Song, Weiwei

    2016-02-01

    This paper proposes an enhanced algorithm to estimate the differential code biases (DCB) on three frequencies of the BeiDou Navigation Satellite System (BDS) satellites. By forming ionospheric observables derived from uncombined precise point positioning and geometry-free linear combination of phase-smoothed range, satellite DCBs are determined together with ionospheric delay that is modeled at each individual station. Specifically, the DCB and ionospheric delay are estimated in a weighted least-squares estimator by considering the precision of ionospheric observables, and a misclosure constraint for different types of satellite DCBs is introduced. This algorithm was tested by GNSS data collected in November and December 2013 from 29 stations of Multi-GNSS Experiment (MGEX) and BeiDou Experimental Tracking Stations. Results show that the proposed algorithm is able to precisely estimate BDS satellite DCBs, where the mean value of day-to-day scattering is about 0.19 ns and the RMS of the difference with respect to MGEX DCB products is about 0.24 ns. In order to make comparison, an existing algorithm based on IGG: Institute of Geodesy and Geophysics, China (IGGDCB), is also used to process the same dataset. Results show that, the DCB difference between results from the enhanced algorithm and the DCB products from Center for Orbit Determination in Europe (CODE) and MGEX is reduced in average by 46 % for GPS satellites and 14 % for BDS satellites, when compared with DCB difference between the results of IGGDCB algorithm and the DCB products from CODE and MGEX. In addition, we find the day-to-day scattering of BDS IGSO satellites is obviously lower than that of GEO and MEO satellites, and a significant bias exists in daily DCB values of GEO satellites comparing with MGEX DCB product. This proposed algorithm also provides a new approach to estimate the satellite DCBs of multiple GNSS systems.

  8. Glacial Refugium of Pinus pumila (Pall.) Regel in Northeastern Siberia

    Energy Technology Data Exchange (ETDEWEB)

    Shilo, N A; Lozhkin, A V; Anderson, P M; Brown, T A; Pakhomov, A Y; Solomatkina, T B

    2007-02-10

    One of the most glowing representatives of the Kolyma flora [1], ''Pinus pumila'' (Pall.) Regel (Japanese stone pine), is a typical shrub in larch forests of the northern Okhotsk region, basins of the Kolyma and Indigirka rivers, and high-shrub tundra of the Chukchi Peninsula. It also forms a pine belt in mountains above the forest boundary, which gives way to the grass-underbrush mountain tundra and bald mountains. In the southern Chukchi Peninsula, ''Pinus pumila'' along with ''Duschekia fruticosa'' (Rupr.) Pouzar and ''Betula middendorffii'' Trautv. et C. A. Mey form trailing forests transitional between tundra and taiga [2]. Pinus pumila pollen, usually predominating in subfossil spore-and-pollen spectra of northeastern Siberia, is found as single grains or a subordinate component (up 2-3%, rarely 10%) in spectra of lacustrine deposits formed during the last glacial stage (isotope stage 2) in the Preboreal and Boreal times of the Holocene. Sometimes, its content increases to 15-22% in spectra of lacustrine deposits synchronous to the last glacial stage near the northern coast of the Sea of Okhotsk [3], evidently indicating the proximity of Japanese stone pine thickets.

  9. A Good Neighborhood for Cells: Bioreactor Demonstration System (BDS-05)

    Science.gov (United States)

    Chung, Leland W. K.; Goodwin, Thomas J. (Technical Monitor)

    2002-01-01

    Good neighborhoods help you grow. As with a city, the lives of a cell are governed by its neighborhood connections Connections that do not work are implicated in a range of diseases. One of those connections - between prostate cancer and bone cells - will be studied on STS-107 using the Bioreactor Demonstration System (BDS-05). To improve the prospects for finding novel therapies, and to identify biomarkers that predict disease progression, scientists need tissue models that behave the same as metastatic or spreading cancer. This is one of several NASA-sponsored lines of cell science research that use the microgravity environment of orbit in an attempt to grow lifelike tissue models for health research. As cells replicate, they "self associate" to form a complex matrix of collagens, proteins, fibers, and other structures. This highly evolved microenvironment tells each cell who is next door, how it should grow arid into what shapes, and how to respond to bacteria, wounds, and other stimuli. Studying these mechanisms outside the body is difficult because cells do not easily self-associate outside a natural environment. Most cell cultures produce thin, flat specimens that offer limited insight into how cells work together. Ironically, growing cell cultures in the microgravity of space produces cell assemblies that more closely resemble what is found in bodies on Earth. NASA's Bioreactor comprises a miniature life support system and a rotating vessel containing cell specimens in a nutrient medium. Orbital BDS experiments that cultured colon and prostate cancers have been highly promising.

  10. Discontinuities of BFKL amplitudes and the BDS ansatz

    Science.gov (United States)

    Fadin, V. S.; Fiore, R.

    2015-12-01

    We perform an examination of discontinuities of multiple production amplitudes, which are required for further development of the BFKL approach. It turns out that the discontinuities of 2 → 2 + n amplitudes obtained in the BFKL approach contradict to the BDS ansatz for amplitudes with maximal helicity violation in N = 4 supersymmetric Yang-Mills theory with large number of colors starting with n = 2. Explicit expressions for the discontinuities of the 2 → 3 and 2 → 4 amplitudes in the invariant mass of pairs of produced gluons are obtained in the planar N = 4 SYM in the next-to-leading logarithmic approximation. These expressions can be used for checking the conjectured duality between the light-like Wilson loops and the MHV amplitudes.

  11. Improving Ambiguity Resolution for Medium Baselines Using Combined GPS and BDS Dual/Triple-Frequency Observations

    Directory of Open Access Journals (Sweden)

    Wang Gao

    2015-10-01

    Full Text Available The regional constellation of the BeiDou navigation satellite system (BDS has been providing continuous positioning, navigation and timing services since 27 December 2012, covering China and the surrounding area. Real-time kinematic (RTK positioning with combined BDS and GPS observations is feasible. Besides, all satellites of BDS can transmit triple-frequency signals. Using the advantages of multi-pseudorange and carrier observations from multi-systems and multi-frequencies is expected to be of much benefit for ambiguity resolution (AR. We propose an integrated AR strategy for medium baselines by using the combined GPS and BDS dual/triple-frequency observations. In the method, firstly the extra-wide-lane (EWL ambiguities of triple-frequency system, i.e., BDS, are determined first. Then the dual-frequency WL ambiguities of BDS and GPS were resolved with the geometry-based model by using the BDS ambiguity-fixed EWL observations. After that, basic (i.e., L1/L2 or B1/B2 ambiguities of BDS and GPS are estimated together with the so-called ionosphere-constrained model, where the ambiguity-fixed WL observations are added to enhance the model strength. During both of the WL and basic AR, a partial ambiguity fixing (PAF strategy is adopted to weaken the negative influence of new-rising or low-elevation satellites. Experiments were conducted and presented, in which the GPS/BDS dual/triple-frequency data were collected in Nanjing and Zhengzhou of China, with the baseline distance varying from about 28.6 to 51.9 km. The results indicate that, compared to the single triple-frequency BDS system, the combined system can significantly enhance the AR model strength, and thus improve AR performance for medium baselines with a 75.7% reduction of initialization time on average. Besides, more accurate and stable positioning results can also be derived by using the combined GPS/BDS system.

  12. Mapping continental-scale biomass burning and smoke palls over the Amazon basin as observed from the Space Shuttle

    Science.gov (United States)

    Helfert, Michael R.; Lulla, Kamlesh P.

    1990-01-01

    Space Shuttle and Skylab-3 photography has been used to map the areal extent of Amazonian smoke palls associated with biomass burning (1973-1988). Areas covered with smoke have increased from approximately 300,000 sq km in 1973 to continental-size smoke palls measuring approximately 3,000,000 sq km in 1985 and 1988. Mapping of these smoke palls has been accomplished using space photography mainly acquired during Space Shuttle missions. Astronaut observations of such dynamic and vital environmental phenomena indicate the possibility of integrating the earth observation capabilities of all space platforms in future Global Change research.

  13. Smoke palls induced by Kuwaiti oilfield fires mapped from Space Shuttle imagery

    Science.gov (United States)

    Lulla, Kamlesh P.; Helfert, Michael R.

    1991-01-01

    Consideration is given to initial observations on the Kuwaiti oilfield fires and the spatial and areal extent of these smoke palls as viewed from the Space Shuttle flights during April/May 1991. It is concluded that one of the early lessons learned from Kuwaiti oilfield fires is that the presence of intelligent observers on orbit is of great value for acquiring data and confirm/deny events.

  14. The hair of the common hare (Lepus europaeus Pall.) and of the common vole (Microtus arvalis Pall.) as indicator of the environmental pollution

    International Nuclear Information System (INIS)

    Hairs of common hare (Lepus europaeus Pall.) and of common vole (Microtus arvalis Pall.) living in immission zones were investigated by INAA. Both the hare and the vole are almost exclusively herbivores; they consume relatively large amounts of contaminated food and reflect reliably the contamination degree of the respective ecosystem. The use of free-living animals for assessing environmental quality may complete effectively the information obtained by the examination of population. Though free-living animals lead a rather different way of existence it has been found that analyses of their hairs correlate very well with analyses of human hair. It may be expected that the changes in concentrations of heavy metals will manifest themselves earlier in animals than in men because the animals are strictly tied to local food sources. The hair samples of hares contained increased concentrations of Sm, La, Au, As, Se, Cr, Sc, Fe, Ce, Th and Co. The hairs of voles showed increased concentrations of Sm, La, Zn, As, Se, Cr, Sc, Fe, Sb, Ce, Cs and Co. A marked trend towards cumulation in hair was observed for the following elements: As, Se, Sc and Fe. The increase of their concentrations in the hairs of animals from the immission regions amounted to as much as 103%. (author)

  15. Convergence Time and Positioning Accuracy Comparison between BDS and GPS Precise Point Positioning

    Directory of Open Access Journals (Sweden)

    ZHANG Xiaohong

    2015-03-01

    Full Text Available BDS/GPS data from MGEX were processed by TriP 2.0 software developed at Wuhan University. Both static and kinematic float PPP are tested by adopting precise satellite orbits and clocks provided by Research Center of GNSS, Wuhan University. The results show that the convergence time of BDS static PPP is about 80min while kinematic PPP is about 100min. For 3h observations, static positioning accuracy of 5 cm and kinematic positioning accuracy of 8 cm in horizontal, about 12 cm in vertical can be achieved. Similar to GPS PPP, precision in east component is worse than north. At present, BDS PPP needs longer convergence time than GPS PPP to reach an absolute positioning accuracy of cm~dm due to the lack of global tracking stations and the limited accuracy of orbit and clock products.

  16. BDS/GPS Dual Systems Positioning Based on the Modified SR-UKF Algorithm

    Directory of Open Access Journals (Sweden)

    JaeHyok Kong

    2016-05-01

    Full Text Available The Global Navigation Satellite System can provide all-day three-dimensional position and speed information. Currently, only using the single navigation system cannot satisfy the requirements of the system’s reliability and integrity. In order to improve the reliability and stability of the satellite navigation system, the positioning method by BDS and GPS navigation system is presented, the measurement model and the state model are described. Furthermore, the modified square-root Unscented Kalman Filter (SR-UKF algorithm is employed in BDS and GPS conditions, and analysis of single system/multi-system positioning has been carried out, respectively. The experimental results are compared with the traditional estimation results, which show that the proposed method can perform highly-precise positioning. Especially when the number of satellites is not adequate enough, the proposed method combine BDS and GPS systems to achieve a higher positioning precision.

  17. The hexagon Wilson loop and the BDS ansatz for the six-gluon amplitude

    OpenAIRE

    Drummond, J M; Henn, J.; Korchemsky, G.P.; Sokatchev, E.

    2007-01-01

    As a test of the gluon scattering amplitude/Wilson loop duality, we evaluate the hexagonal light-like Wilson loop at two loops in N=4 super Yang-Mills theory. We compare its finite part to the Bern-Dixon-Smirnov (BDS) conjecture for the finite part of the six-gluon amplitude. We find that the two expressions have the same behavior in the collinear limit, but they differ by a non-trivial function of the three (dual) conformally invariant variables. This implies that either the BDS conjecture o...

  18. Estimating the yaw-attitude of BDS IGSO and MEO satellites

    Science.gov (United States)

    Dai, Xiaolei; Ge, Maorong; Lou, Yidong; Shi, Chuang; Wickert, Jens; Schuh, Harald

    2015-10-01

    Precise knowledge and consistent modeling of the yaw-attitude of GNSS satellites are essential for high-precision data processing and applications. As the exact attitude control mechanism for the satellites of the BeiDou Satellite Navigation System (BDS) is not yet released, the reverse kinematic precise point positioning (PPP) method was applied in our study. However, we confirm that the recent precise orbit determination (POD) processing for GPS satellites could not provide suitable products for estimating BDS attitude using the reverse PPP because of the special attitude control switching between the nominal and the orbit-normal mode. In our study, we propose a modified processing schema for studying the attitude behavior of the BDS satellites. In this approach, the observations of the satellites during and after attitude switch are excluded in the POD processing, so that the estimates, which are needed in the reverse PPP, are not contaminated by the inaccurate initial attitude mode. The modified process is validated by experimental data sets and the attitude yaw-angles of the BDS IGSO and MEO satellites are estimated with an accuracy of better than . Furthermore, the results confirm that the switch is executed when the Sun elevation is about and the actual orientation is very close to its target one. Based on the estimated yaw-angles, a preliminary attitude switch model was established and reintroduced into the POD, yielding to a substantial improvement in the orbit overlap RMS.

  19. An Accurate Method for the BDS Receiver DCB Estimation in a Regional Network

    Directory of Open Access Journals (Sweden)

    LI Xin

    2016-08-01

    Full Text Available An accurate approach for receiver differential code biases (DCB estimation is proposed with the BDS data obtained from a regional tracking network. In contrast to the conventional methods for BDS receiver DCB estimation, the proposed method does not require a complicated ionosphere model, as long as one reference station receiver DCB is known. The main idea for this method is that the ionosphere delay is highly dependent on the geometric ranges between the BDS satellite and the receiver normally. Therefore, the non-reference station receivers DCBs in this regional area can be estimated using single difference (SD with reference stations. The numerical results show that the RMS of these estimated BDS receivers DCBs errors over 30 days are about 0.3 ns. Additionally, after deduction of these estimated receivers DCBs and knowing satellites DCBs, the extractive diurnal VTEC showed a good agreement with the diurnal VTEC gained from the GIM interpolation, indicating the reliability of the estimated receivers DCBs.

  20. Sensitivity requirements of assisted BDS and GPS in specification 3GPP TS 36.171

    Science.gov (United States)

    Jin, Xiaoxi; Chen, Xin; Ying, Rendong; Yang, Genke

    2016-01-01

    With the needs of growing location-based service, a more high-performance satellite positioning technology - assisted global navigation satellite system (A-GNSS assisted-GNSS) becomes a new hotspot in area of navigation and positioning. Now, 3GPP has already provided supports for GPS, Galileo, GLONASS and QZSS, SBAS, so standardization work of introduction BDS into 3GPP organization is very imperative. In this paper, we first analysis the performance of GPS L1 C/A with assistant information, then by taking into account the difference between BDS and GPS, including the unique nature of GEO/NGEO satellites' navigation message data length and format, we design the sensitivity requirements of BDS B1 following A-GPS. The results between A-GPS and A-BDS of typical sensitivity test cases are shown in this paper, which show that the suggested sensitivity requirements satisfy the minimum performance requirements under technical specification of 3GPP TS 36.171.

  1. The BDS iGMAS RIOS station at Observatório Nacional, Rio de Janeiro

    Science.gov (United States)

    Humberto Andrei, Alexandre; Song, Shuli; Junqueira, Selma; Beauvalet, Laurene

    2016-07-01

    GNSS navigation satellites are currently being developed by all major players in the science and technology scene, to compete with the GPS system. Because their applications span many different areas, from traffic and cargo control, to geodesy and seismic monitoring, it is required to assess the coherence between the different constellations. BDS is the GNSS system currently developed in China. Its first generation of satellites consisted of 3 geostationnary satellites allowing geolocalisation in China only. In addition to these satellites, other satellites have been launched in geostationnary and geosynchronous orbits, as well as satellites orbiting with a classical GNSS semi-major axis. With these additions, the BDS system possesses 19 operating satellites, and though the system is mostly efficient for geolocalisation in Asia, the satellites are also visible in other parts of the globe. In parallel to the development of the BDS constellation, China has launched the iGMAS (International GNSS Monitoring and Assessment Service) project to develop a global tracking network of multi-GNSS geodetic receivers. One of the goals of this project is to evaluate the efficiency of the BDS constellation as well as the efficiency of the receivers developed by the Chinese laboratories. As part of the Brazilian program COSBAN leaded by the Foreign Affairs Ministry to foster up the science and technology partnership with China, materialized by the collaboration between the Shanghai Astronomical Observatory/CAS and the Observatório Nacional/MCTI, in Rio de Janeiro. Through it the RIOS-iGMAS station was installed at Observatório Nacional, where the RJEP GNSS station already operates as part of the Brazilian reference system. Thus at the Observatório Nacional can be observed satellites from any constellation with both systems of reception, leading to a direct, efficient way to compare the results obtained for each network. In this communication we focus on the determination of the

  2. SEASONAL AND AGE VARIATIONS OF BERBERINE CONTENT IN INTRODUCED BERBERIS SIBIRICA PALL.

    OpenAIRE

    Иван Васильевич Нечепуренко; Нина Ивановна Комарова; Олег Николаевич Потёмкин; Нариман Фаридович Салахутдинов

    2014-01-01

    The content of isoquinoline alkaloid berberine was studied by means of HPLC in the roots and the above-ground part of introduced Berberis sibirica Pall. of various ages collected during different periods of three vegetative seasons. The roots contain 3–5 times more berberine than the stems. The content of berberine in 7-year-old roots varies slightly during the season; its mean value was 1.10% and maximum content was found in July (1,16±0.03%). The roots of the age of 3 years contain fewer be...

  3. Analysis of Essential Oils from Flower-buds, Leaves and Stems of Filipendula palmata (Pall.) Maxim.

    Institute of Scientific and Technical Information of China (English)

    WU Yin; MENG Xiang-ying; LIU Xiao-hua; BAO Yong-li; WANG Shu-ping; LI Yu-xin

    2005-01-01

    The essential oils of the flower-buds, leaves and stems of Filipendula palmata (Pall.) Maxim. were analyzed by GC and GC-MS. Thirty-three, forty-seven and forty-seven compounds in the flower-buds, leaves and stems were identified, respectively. Methyl salicylate exists in a great amount which is up to 70. 10% in the flower-buds. Its amount is also high in other two parts. The data obtained show that it may be one of the main natural mosquito-expelling and pain-alleviating components in the three parts. The flower-buds are the main active part with the mosquito-expelling function.

  4. Color suppressed contributions to the decay modes B_{d,s} -> D_{s,d} D_{s,d}, B_{d,s} -> D_{s,d} D^*_{s,d}, and B_{d,s} -> D^*_{s,d} D^*_{s,d}

    OpenAIRE

    Eeg, Jan O.; Fajfer, Svjetlana; Prapotnik, Anita

    2005-01-01

    The amplitudes for decays of the type $B_{d,s} \\to D_{s,d} D_{s,d}$, have no factorizable contributions, while $B_{d,s} \\to D_{s,d} D^*_{s,d}$, and $B_{d,s} \\to D^*_{s,d} D^*_{s,d}$ have relatively small factorizable contributions through the annihilation mechanism. The dominant contributions to the decay amplitudes arise from chiral loop contributions and tree level amplitudes which can be obtained in terms of soft gluon emissions forming a gluon condensate. We predict that the branching rat...

  5. BDS/GPS Dual Systems Positioning Based on the Modified SR-UKF Algorithm

    OpenAIRE

    JaeHyok Kong; Xuchu Mao; Shaoyuan Li

    2016-01-01

    The Global Navigation Satellite System can provide all-day three-dimensional position and speed information. Currently, only using the single navigation system cannot satisfy the requirements of the system’s reliability and integrity. In order to improve the reliability and stability of the satellite navigation system, the positioning method by BDS and GPS navigation system is presented, the measurement model and the state model are described. Furthermore, the modified square-root Unscented K...

  6. Performance Analysis of BDS Satellite Orbits during Eclipse Periods: Results of Satellite Laser Ranging Validation

    Directory of Open Access Journals (Sweden)

    PENG Hanbing

    2016-06-01

    Full Text Available The performance of BeiDou satellite orbits during eclipse periods is an important part of the performance analysis of BeiDou Navigation Satellite System (BDS. Accuracy evaluation of satellite orbits in ephemeris of BDS during eclipse periods can provide support for the service performance assessment. It also helps to find possible deficiencies in the orbit modeling during eclipse periods, which may further contribute to the improvements of functional models for precise orbit determination. The effects of eclipse periods on the orbits of the three types of satellites of BDS are analyzed with the satellite laser ranging (SLR observations ranging from January 2014 to July 2015. At the same time, the orbit radial accuracy of BDS broadcast and precise ephemeris are validated. The results show that, obvious orbit accuracy decrease can be observed in both broadcast and precise ephemeris for IGSO/MEO satellites during eclipse periods (especially the yaw-maneuver periods. And orbit radial errors of IGSO/MEO satellites in broadcast ephemeris reach 1.5~2.0 m, and exceed 10.0 cm for that in precise ephemeris. Performance decrease of the GEO satellite orbit during eclipse arcs can hardly be revealed by the orbit radial residual series. During non-eclipse periods, radial accuracy of IGSO/MEO and GEO satellite orbits in broadcast ephemeris are better than 0.5 m and 0.9 m respectively. The radial accuracy of IGSO/MEO satellite orbits in precise ephemeris are better than 10.0 cm and that of the GEO satellite is about 50.0 cm with a systematic bias of 40.0 cm around.

  7. Analysis and compensation for code Doppler effect of BDS II signal under high dynamics

    Science.gov (United States)

    Ouyang, Xiaofeng; Zeng, Fangling

    2016-01-01

    In high dynamic circumstances, the acquisition of BDS (BeiDou Navigation Satellite System) signal would be affected by the pseudo-code Doppler. The pseudo-code frequency shift is more prominent and complex when BOC modulation has been adopted by BDS-II, but is not yet involved in current compensation algorithm. In addition, the most frequently used code Doppler compensation algorithm is modifying the sampling rate or local bit rate, which not only increases the complexity of the acquisition and tracking, but also is barely realizable for the hardware receiver to modify the local frequency. Therefore, this paper proposes a code Doppler compensation method based on double estimator receiver, which simultaneously controls NCO delay of code tracking loop and subcarrier tracking loop to compensate for pseudo-code frequency shift. The simulation and test are implemented with BDS-II BOC signal. The test results demonstrate that the proposed algorithm can effectively compensate for pseudo-code Doppler of BOC signal and has detection probability 3dB higher than the uncompensated situation when the false alarm rate is under 0.01 and the coherent integration time is 1ms.

  8. Tusen och en pall : Formgivning med ett mervärde

    OpenAIRE

    Snellman, Anna

    2013-01-01

    Som examensarbete har jag i samarbete med en åländsk textilhantverkare utvecklat och tillverkat en liten serie sittmöbler. Denna serie består av en pall och en bänk som båda har det där lilla extra. I detta fall en textil som främjar den sociala utvecklingen i Indien, som handvävs på Åland och som i framtiden förhoppningsvis förgyller de finska folkhemmen. Både de teoretiska och praktiska delarna i arbetet fokuserar på etisk design. Jag disponerar arbetet på ett sätt som först behandlar olika...

  9. Biological consequences of increased natural radiation background for Microtus oeconomus Pall. populations

    Energy Technology Data Exchange (ETDEWEB)

    Kudyasheva, Alevtina G. [Radioecology Department, Institute of Biology, Komi Scientific Center, Ural Division RAS, 28 Kommunisticheskaya ul., Syktyvkar 167982, Komi Republic (Russian Federation); Shishkina, Ludmila N. [Emanuel Institute of Biochemical Physics RAS, Kosygina 4, Moscow 119991 (Russian Federation); Shevchenko, Oksana G. [Radioecology Department, Institute of Biology, Komi Scientific Center, Ural Division RAS, 28 Kommunisticheskaya ul., Syktyvkar 167982, Komi Republic (Russian Federation)], E-mail: shevchenko@ib.komisc.ru; Bashlykova, Ludmila A.; Zagorskaya, Nadezhda G. [Radioecology Department, Institute of Biology, Komi Scientific Center, Ural Division RAS, 28 Kommunisticheskaya ul., Syktyvkar 167982, Komi Republic (Russian Federation)

    2007-09-15

    The results of long-term investigations (1981-1999) on the state of Microtus oeconomus Pall. (tundra vole) population, living under the increased natural radiation background for a long time (for more than 100 generations), are presented. Population density dynamics, morphophysiological parameters, state of the lipid peroxidation regulatory system in different tissues and the cytogenetic effects in bone marrow cells of animals have been analyzed. It is shown that tundra voles from the studied radioactively contaminated areas differ from those on natural radiation background area for the parameters measured. The results of this long-term investigation show that qualitatively new sub-populations of tundra vole on these areas have evolved, which are able to survive in radioactively contaminated environment.

  10. 盐地碱蓬的染色体核型分析%Karyotype analysis of Suaeda salsa (L.) Pall

    Institute of Scientific and Technical Information of China (English)

    张峰; 姚燕

    2013-01-01

    The paper originally analyzes the number of chromosomes and karyotype of Suaeda salsa (L. ) Pall. Results show that its chromosome number is 2n =18, and that its karyotype formula is K(2n) =2x = 18 = 16m +2sm. The karyotype is 1A based on the classification standard of Stebbins.%本文首次对盐地碱蓬(Suaeda salsa(L.)Pall.)的染色体数目和核型进行了分析研究.结果表明,盐地碱蓬的染色体数目2n=18,核型公式为K(2n)=18=16m +2sm.根据Stebbins的核型分类标准,盐地碱蓬的核型属1A型.

  11. Análisis de las deficiencias del test BDS en series temporales univariantes

    Directory of Open Access Journals (Sweden)

    Pedro A. Pérez Pascual

    2002-01-01

    Full Text Available El test BDS de Brock, Dechert y Scheinkman es un test asintótico que proporciona una herramienta no paramétrica para contrastar la hipótesis nula de series i.i.d., con potencia, en teoría, sobre todas las alternativas restantes (lineales y no lineales, estocásticas y deterministas. Recientemente una versión del BDS ha sido implementada en el E-views, motivo por el que la herramienta ganará difusión dentro del análisis econométrico. Desafortunadamente, con anterioridad a esta reciente implementación y aún en la actualidad, se han observado ciertas deficiencias en la potencia y tamaño del test para muestras finitas; la sensibilidad del test ante ciertos parámetros del mismo y en el modo de evaluar los resultados; etc. Estas deficiencias, y otras nuevas, son expuestas y analizadas ofreciendo explicaciones cuando esto es posible.

  12. Alkaloids of Nitraria sibirica Pall. decrease hypertension and albuminuria in angiotensin II-salt hypertension.

    Science.gov (United States)

    Bakri, Mahinur; Yi, Yang; Chen, Ling-Dan; Aisa, Haji Akber; Wang, Mong-Heng

    2014-04-01

    In traditional Chinese medicine, Nitraria sibirica Pall. (Nitrariaceae) is used to treat hypertension. This study determined the effects of the total alkaloids of the leaves of Nitraria sibirica (NSTA) on blood pressure and albuminuria in mice treated with angiotensin II and a high-salt diet (ANG/HS). Adult mice were divided into three groups: control; infused with angiotensin II and fed a diet containing 4% NaCl (ANG/HS; and ANG/HS plus injection of NSTA (1 mg·kg(-1)·d(-1), i.p.). After treatment of these regimens, daily water and food intake, kidney weight, blood pressure, urinary albumin excretion, renal concentrations of inflammatory markers, including soluble intercellular adhesion molecule-1 (sICAM-1) and monocyte chemoattractant protein-1 (MCP-1), and the expression of renal fibrosis markers were determined. Compared to the control group, the ANG/HS group had higher blood pressure and urinary albumin excretion. Treatment with NSTA in ANG/HS mice for three weeks significantly reduced blood pressure and urinary albumin excretion. ANG/HS treatment caused elevated levels of sICAM-1 and MCP-1, as well as increased fibrosis markers. Concurrent treatment with ANG/HS and NSTA attenuated the levels and expression of renal inflammatory and fibrosis markers. Treatment with NSTA effectively reduces hypertension-induced albuminuria through the reduction of renal inflammatory and fibrosis markers. PMID:24863351

  13. Relationship between Major Mineral Nutrient Elements Contents and Flower Colors of Herbaceous Peony (Paeonia Lactiflora Pall.

    Directory of Open Access Journals (Sweden)

    Chengzhong Li

    2015-02-01

    Full Text Available Herbaceous peony (Paeonia lactiflora Pall. is a famous ornamental plant with bright flowers and lush leaves. The flower petal can be used as a fragrant food additive. Understanding the mineral nutrient contents in P. lactiflora is necessary for guiding its cultivation practices as well as its use as a food additive. In this study, we investigated the mineral contents including Calcium (Ca, Potassium (K, Magnesium (Mg, Copper (Cu, iron (Fe and Zinc (Zn in petals and leaves of 20 selected herbaceous peony cultivars in four groups according to their flower colors and the relationship between major mineral nutrient elements contents and flower colors was assessed. In petals, the contents of minerals were in this order K>Ca>Mg>Fe>Zn>Cu; while in leaves were: Ca>K>Mg>Fe>Zn>Cu. Major element contents in petals and leaves among 4 cultivar groups were different at statistically significant levels. Petals in red or purple have higher amount of most major minerals than those in white or pink colors. The wide range of mineral element contents among cultivars is attributed to genotypic variations. The correlations of major mineral elements in the petals and leaves of herbaceous peony cultivars indicate that mineral ions compete for the same absorption sites. The results provided some scientific support for petal nutrition of herbaceous peony and selecting herbaceous peony flowers with dark colors for edible is feasible.

  14. The Root Extract of Gentiana macrophylla Pall. Alleviates Cardiac Apoptosis in Lupus Prone Mice.

    Directory of Open Access Journals (Sweden)

    Chih-Yang Huang

    Full Text Available The roots of the perennial herb Gentiana macrophylla Pall. (GM are known as Qinjiao, which has been used for centuries to treat systemic lupus erythematosus (SLE. However, little is known about the effects of GM on cholesterol-aggravated cardiac abnormalities in SLE, and the mechanisms thereof. This study investigates whether GM exhibits anti-apoptotic effects, focusing on the left ventricle (LV of NZB/W F1 mice fed with high-cholesterol diet. The morphology and apoptotic status of ventricular tissues were determined by microscopy and Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL assay. Levels of apoptotic biomarkers were determined by immunoblotting. The results thus obtained revealed that GM significantly reduced the cholesterol-aggravated apoptosis of LV in NZB/W F1 mice by suppressing both intrinsic and extrinsic apoptotic pathways. Additionally, GM significantly increased the cardiac insulin-like growth factors (IGF-1 survival signaling and anti-apoptotic proteins in LV tissues. Accordingly, GM is considered to be beneficial in alleviating cholesterol-aggravated cardiac damage in SLE, and therefore constitute an alternative treatment for SLE patients with cardiac abnormalities.

  15. Study of Charmless Bd,s0 → h+h'-π0 decays in LHCb

    International Nuclear Information System (INIS)

    This thesis work is about the identification of charmless three-body decays of neutral B mesons with a π0 in the final state (Bd,s0 → h+h'-π0) through the analysis of a 1.0 fb-1 data sample collected in 2011 by the LHCb experiment at the LHC. Those modes are sensitive to CKM parameters and allow to test Standard Model predictions related to CP violation. Some of them, such as Bs0 → K-π+π0 and Bs0 → K+K-π0, have not been observed previously. This is the first analysis with energetic π0 in LHCb. To evaluate the detector performance for π0, D*+ → D0 (→ K-π+π0)π+ decays have been selected. This provides a clean and high statistics sample of neutral pions used to study their energy calibration as well as the effectiveness of the π0/γ separation tool of the experiment. Radiative decays are indeed the most dangerous backgrounds for the study of Bd,s0 → h+h'-π0 modes. To select Bd,s0 → h+h'-π0 events, a dedicated trigger algorithm has been implemented. It complements the standard online selections and significantly improves the efficiency. Offline, obvious backgrounds, mainly from charm decays, are rejected applying simple criteria. The sample is then further purified using a multivariate classifier. At last, information from the ring imaging Cherenkov detectors allows to separate π+π-π0, K±π±π0 and K+K-π0 final states. A simultaneous fit of the reconstructed B mass spectra in the three sub-samples is used to extract the signal yields. It accounts for the different backgrounds remaining as well as for the signal cross-feeds from one sub-sample to the other. The B0 → π+π-π0, B0 → K+π-π0 and Bs0 → K+K-π0 contributions are clearly established. This is the first observation of the Bs0 → K+K-π0 decay mode. (author)

  16. CAC AND BDS FOR MAXIMIZING THE CAPACITY OF ENHANCED 3G NETWORK

    Directory of Open Access Journals (Sweden)

    Er. SONIA JINDAL,

    2010-10-01

    Full Text Available The crucial issues in cellular network for service provider is to provide the guaranteed quality of service (QoS, minimizing the dropping rate (DR for handoff calls, blocking rate (BR for new calls and most important is to increasing the capacity of network . This paper purposes two concepts in WCDMA network i.e call admissioncontrol (CAC by considering distance of the cell as a deciding factor in order to minimize BR and DR .Our work is useful in the case when call can not transfer to lightly loaded cell as done in load balancing with cell breathing concept and blocked due to non availability of bandwidth then bandwidth degradation scheme (BDS is used to increase the capacity of a cell/overall network and also to assign priority to the handoff calls over new call.

  17. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT PHYSICAL REMOVAL OF CRYPTOSPORIDIUM OOCYSTS AND GIARDIA CYSTS IN DRINKING WATER PALL CORPORATION WPM-1 MICROFILTRATION SYSTEM AT PITTSBURGH, PA - NSF 00/09/EPADW395

    Science.gov (United States)

    Verification testing of the Pall Corporation WPM-1 Microfiltration Pilot System was conducted from February 3 to March 5, 1999. The Pall WPM-1 membrane is a hollow fiber type microfiltration membrane made of polyvinylidenefluoride (PVDF). It has a 0.1 micrometer ( m) nominal por...

  18. Identification of miRNAs Responsive to Botrytis cinerea in Herbaceous Peony (Paeonia lactiflora Pall.) by High-Throughput Sequencing

    OpenAIRE

    Daqiu Zhao; Saijie Gong; Zhaojun Hao; Jun Tao

    2015-01-01

    Herbaceous peony (Paeonia lactiflora Pall.), one of the world’s most important ornamental plants, is highly susceptible to Botrytis cinerea, and improving resistance to this pathogenic fungus is a problem yet to be solved. MicroRNAs (miRNAs) play an essential role in resistance to B. cinerea, but until now, no studies have been reported concerning miRNAs induction in P. lactiflora. Here, we constructed and sequenced two small RNA (sRNA) libraries from two B. cinerea-infected P. lactiflora cul...

  19. Perception of BDS students and fresh graduates about significance of professional ethics in dentistry

    International Nuclear Information System (INIS)

    Objective: To assess the awareness level of undergraduate dentistry students as well as fresh graduates about the significance of professional ethics. Methods: The cross sectional study was conducted among the 3rd, 4th and final year male and female BDS students as well as fresh graduate Interns from the College of Dentistry, King Saud University from January to June 2011. The students were asked to give their opinion about need for applications of professional ethics in dental practice on a five point Likert Scale varying from strongly agree to strongly disagree. Minitab statistical software was used for data analysis. Results: Students at all levels considered professional ethics a very important prerequisite for dental practice with overall mean value of 4.42+-0.36. However, the responses from the senior academic levels were significantly on the higher side compared to those from the junior grades. Generally the religious teachings and spirituality was considered as one of the top most motives for practicing professional ethics in dentistry followed by reputation, financial benefits, fear of punishment and self projection, with overall mean values of 3.93+-0.58, 3.81+-0.49, 3.25+-0.94, 3.21+-1.07 and 3.16+-1.04, respectively. Conclusion: The present findings revealed that Professional Ethics is appreciated by the students as a highly significant factor for their success in dental practice as well as acquiring a good name and position in the society. (author)

  20. LHCb: Measurement of the relative yields of the decay modes $B_{d,s} \\to D^{\\pm}_{(s)}\\pi^{\\mp}$ and $B_{d,s} \\to D^{\\pm}_{(s)} K^{\\pm}$ and determination of $f_d /f_s$ for 7 TeV $pp$ collisions

    CERN Multimedia

    David, P; Morawski, P; Witek, M; Akiba, K; Serra, N; Storaci, B; Tuning, N; Williams, M; Easo, S; Carson, L; Poluektov, A

    2011-01-01

    A fit to the invariant mass distributions is used to determine the relative abundances of the four decay modes $B_{d,s} \\to D^{\\pm}_{(s)}\\pi^{\\mp}$ and $B_{d,s} \\to D^{\\pm}_{(s)} K^{\\mp}$ for $B_{d,s}$ mesons produced in 7 TeV $pp$ collisions at the LHC. From these, the relative branching fractions of the kaon modes with respect to the pion modes, and the value of $f_d /f_s$, are determined.

  1. Study of train positioning method based on BDS/GSM-R co mbination%基于 BDS/GSM-R 组合列车定位方法的研究

    Institute of Scientific and Technical Information of China (English)

    李卫东; 侯丽虹; 王友生

    2016-01-01

    针对卫星定位容易丢失信号的问题,提出北斗卫星导航技术与 GSM-R 技术相结合的定位方法。根据哈尔滨西至长春铁路线的实测数据,利用 BP 神经网络构造 BDS /GSM-R 定位信息的融合模型,采用遗传算法优化 BP 神经的权值和阈值,对比优化前和优化后的 BDS /GSM-R 组合定位方法。实验结果表明:优化后的 BP 神经网络训练结果与列车实际运行轨迹偏差更小,东向、北向、方位角定位误差的波动范围明显减小,可以保持列车定位的连续性和精确性。%Aiming at the problem that satellite positioning signal is easily lost,the positioning method that com-bine BeiDou satellite navigation technology with GSM-R technology was put forward.According to the measured data from the Harbin West railway station to Changchun,onethe BDS /GSM -R positioning information fusion model was firstly built using BP neural network structure.The BP neural weights and thresholds were optimized using genetic algorithm.Finally,the results before and after optimization of combined BDS /GSM-R positioning method was compared..The results show that the difference between the training results of BP neural network after optimization and the practical operation tracks of train is reduced.The range of error located in the east and northoriention and azimuth error are obviously decreased.This method can keep the continuity and precision of train positioning.

  2. An Enhanced Box-Wing Solar Radiation pressure model for BDS and initial results

    Science.gov (United States)

    Zhao, Qunhe; Wang, Xiaoya; Hu, Xiaogong; Guo, Rui; Shang, Lin; Tang, Chengpan; Shao, Fan

    2016-04-01

    Solar radiation pressure forces are the largest non-gravitational perturbations acting on GNSS satellites, which is difficult to be accurately modeled due to the complicated and changing satellite attitude and unknown surface material characteristics. By the end of 2015, there are more than 50 stations of the Multi-GNSS Experiment(MGEX) set-up by the IGS. The simple box-plate model relies on coarse assumptions about the dimensions and optical properties of the satellite due to lack of more detailed information. So, a physical model based on BOX-WING model is developed, which is more sophisticated and more detailed physical structure has been taken into account, then calculating pressure forces according to the geometric relations between light rays and surfaces. All the MGEX stations and IGS core stations had been processed for precise orbit determination tests with GPS and BDS observations. Calculation range covers all the two kinds of Eclipsing and non-eclipsing periods in 2015, and we adopted the un-differential observation mode and more accurate values of satellite phase centers. At first, we tried nine parameters model, and then eliminated the parameters with strong correlation between them, came into being five parameters of the model. Five parameters were estimated, such as solar scale, y-bias, three material coefficients of solar panel, x-axis and z-axis panels. Initial results showed that, in the period of yaw-steering mode, use of Enhanced ADBOXW model results in small improvement for IGSO and MEO satellites, and the Root-Mean-Square(RMS) error value of one-day arc orbit decreased by about 10%~30% except for C08 and C14. The new model mainly improved the along track acceleration, up to 30% while in the radial track was not obvious. The Satellite Laser Ranging(SLR) validation showed, however, that this model had higher prediction accuracy in the period of orbit-normal mode, compared to GFZ multi-GNSS orbit products, as well with relative post

  3. Performance Analysis on Carrier Phase-Based Tightly-Coupled GPS/BDS/INS Integration in GNSS Degraded and Denied Environments

    Directory of Open Access Journals (Sweden)

    Houzeng Han

    2015-04-01

    Full Text Available The integration of Global Navigation Satellite Systems (GNSS carrier phases with Inertial Navigation System (INS measurements is essential to provide accurate and continuous position, velocity and attitude information, however it is necessary to fix ambiguities rapidly and reliably to obtain high accuracy navigation solutions. In this paper, we present the notion of combining the Global Positioning System (GPS, the BeiDou Navigation Satellite System (BDS and low-cost micro-electro-mechanical sensors (MEMS inertial systems for reliable navigation. An adaptive multipath factor-based tightly-coupled (TC GPS/BDS/INS integration algorithm is presented and the overall performance of the integrated system is illustrated. A twenty seven states TC GPS/BDS/INS model is adopted with an extended Kalman filter (EKF, which is carried out by directly fusing ambiguity fixed double-difference (DD carrier phase measurements with the INS predicted pseudoranges to estimate the error states. The INS-aided integer ambiguity resolution (AR strategy is developed by using a dynamic model, a two-step estimation procedure is applied with adaptively estimated covariance matrix to further improve the AR performance. A field vehicular test was carried out to demonstrate the positioning performance of the combined system. The results show the TC GPS/BDS/INS system significantly improves the single-epoch AR reliability as compared to that of GPS/BDS-only or single satellite navigation system integrated strategy, especially for high cut-off elevations. The AR performance is also significantly improved for the combined system with adaptive covariance matrix in the presence of low elevation multipath related to the GNSS-only case. A total of fifteen simulated outage tests also show that the time to relock of the GPS/BDS signals is shortened, which improves the system availability. The results also indicate that TC integration system achieves a few centimeters accuracy in

  4. A geometry-free and ionosphere-free multipath mitigation method for BDS three-frequency ambiguity resolution

    Science.gov (United States)

    Chen, Dezhong; Ye, Shirong; Xia, Jingchao; Liu, Yanyan; Xia, Pengfei

    2016-04-01

    Because of the unknown systematic errors and special satellite constellations in the Beidou system (BDS), it is difficult to quickly and reliably determine the ambiguity over long-range baselines in continuously operating reference station (CORS) network. This study seeks to improve the effectiveness and reliability of BDS ambiguity resolution (AR) by combining the geometry-free and ionosphere-free (GFIF) combination and multipath mitigation algorithm. The GFIF combination composed with three-frequency signals is free of distance-dependent errors and can be used to determine the narrow lane ambiguity. The presence of multipath errors means that not all ambiguities can be correctly achieved by rounding the averaged GFIF ambiguity series. A multipath model of the single-differenced (SD) GFIF combination from the previous period is established for each individual satellite. This model is subtracted from the SD GFIF combination for the current day to remove the effects of multipath errors. Using three triangle networks with lengths of approximately 120, 80 and 50 km, we demonstrate that the proposed method improves the AR performance. The ambiguity averaged first fixing time is typically less than 1801 s for inclined geosynchronous orbit (IGSO) and medium earth orbit (MEO) satellites and less than 2007 s for the ˜ 42° elevation geostationary earth orbit (GEO) C02 satellite. However, it is more time consuming for the low-elevation GEO satellites C04 (˜ 18°) and C05 (˜ 28°). Kalman filtering is used to estimate the troposphere delays and two unfixed ambiguities by employing the ionosphere-free observations of all ambiguity-fixed/unfixed satellites. The experimental results show that only tens of seconds are required for AR in around 90 km baselines.

  5. A geometry-free and ionosphere-free multipath mitigation method for BDS three-frequency ambiguity resolution

    Science.gov (United States)

    Chen, Dezhong; Ye, Shirong; Xia, Jingchao; Liu, Yanyan; Xia, Pengfei

    2016-08-01

    Because of the unknown systematic errors and special satellite constellations in the Beidou system (BDS), it is difficult to quickly and reliably determine the ambiguity over long-range baselines in continuously operating reference station (CORS) network. This study seeks to improve the effectiveness and reliability of BDS ambiguity resolution (AR) by combining the geometry-free and ionosphere-free (GFIF) combination and multipath mitigation algorithm. The GFIF combination composed with three-frequency signals is free of distance-dependent errors and can be used to determine the narrow lane ambiguity. The presence of multipath errors means that not all ambiguities can be correctly achieved by rounding the averaged GFIF ambiguity series. A multipath model of the single-differenced (SD) GFIF combination from the previous period is established for each individual satellite. This model is subtracted from the SD GFIF combination for the current day to remove the effects of multipath errors. Using three triangle networks with lengths of approximately 120, 80 and 50 km, we demonstrate that the proposed method improves the AR performance. The ambiguity averaged first fixing time is typically less than 1801 s for inclined geosynchronous orbit (IGSO) and medium earth orbit (MEO) satellites and less than 2007 s for the ˜ 42° elevation geostationary earth orbit (GEO) C02 satellite. However, it is more time consuming for the low-elevation GEO satellites C04 (˜ 18°) and C05 (˜ 28°). Kalman filtering is used to estimate the troposphere delays and two unfixed ambiguities by employing the ionosphere-free observations of all ambiguity-fixed/unfixed satellites. The experimental results show that only tens of seconds are required for AR in around 90 km baselines.

  6. Identification of miRNAs Responsive to Botrytis cinerea in Herbaceous Peony (Paeonia lactiflora Pall. by High-Throughput Sequencing

    Directory of Open Access Journals (Sweden)

    Daqiu Zhao

    2015-09-01

    Full Text Available Herbaceous peony (Paeonia lactiflora Pall., one of the world’s most important ornamental plants, is highly susceptible to Botrytis cinerea, and improving resistance to this pathogenic fungus is a problem yet to be solved. MicroRNAs (miRNAs play an essential role in resistance to B. cinerea, but until now, no studies have been reported concerning miRNAs induction in P. lactiflora. Here, we constructed and sequenced two small RNA (sRNA libraries from two B. cinerea-infected P. lactiflora cultivars (“Zifengyu” and “Dafugui” with significantly different levels of resistance to B. cinerea, using the Illumina HiSeq 2000 platform. From the raw reads generated, 4,592,881 and 5,809,796 sRNAs were obtained, and 280 and 306 miRNAs were identified from “Zifengyu” and “Dafugui”, respectively. A total of 237 conserved and 7 novel sequences of miRNAs were differentially expressed between the two cultivars, and we predicted and annotated their potential target genes. Subsequently, 7 differentially expressed candidate miRNAs were screened according to their target genes annotated in KEGG pathways, and the expression patterns of miRNAs and corresponding target genes were elucidated. We found that miR5254, miR165a-3p, miR3897-3p and miR6450a might be involved in the P. lactiflora response to B. cinerea infection. These results provide insight into the molecular mechanisms responsible for resistance to B. cinerea in P. lactiflora.

  7. Correlations Between Foliar Stable Carbon Isotope Composition and Environ-mental Factors in Desert Plant Reaumuria soongorica (Pall.) Maxim.

    Institute of Scientific and Technical Information of China (English)

    Jian-Ying MA; Tuo CHEN; Wei-Ya QIANG; Gang WANG

    2005-01-01

    Leaves of 407 individuals of Reaumuria soongorica (Pall.) Maxim. collected from the major distribution areas were measured to investigate the distribution characteristics of the stable carbon isotope in this desert plant, as well as correlations between δ13C values and environmental factors. Results showed that δ13C values in R. soongorica ranged from-22.77‰. to-29.85‰. and that the mean δ13C value (-26.52‰)was higher than a previously reported δ13C value for a different desert ecosystem. This indicates that R.soongorica belongs to the C3 photosynthetic pathway and has higher water use efficiency than other species. The correlations between δ13C values and environmental factors demonstrated that the foliar δ13C values in R. soongorica increased significantly with decreasing mean annual precipitation and mean relative humidity, and decreased with decreasing duration of sunshine and evaporation. The spatial distribution trend of δ13C values in R. soongorica was not obvious and there was no significant correlation between the δ13C values and mean annual temperature. We conclude that different distribution trends in δ13C values for R. soongorica were likely caused by stomatal limitation rather than by nutrient-related changes in photosynthetic efficiency and that precipitation played an important role in the wide distribution range of R.soongorica. This pattern of δ13C values for R. soongorica reinforced that it is a super-xerophil in terms of its adaptive strategies to a desert environment.

  8. Identification of miRNAs Responsive to Botrytis cinerea in Herbaceous Peony (Paeonia lactiflora Pall.) by High-Throughput Sequencing.

    Science.gov (United States)

    Zhao, Daqiu; Gong, Saijie; Hao, Zhaojun; Tao, Jun

    2015-01-01

    Herbaceous peony (Paeonia lactiflora Pall.), one of the world's most important ornamental plants, is highly susceptible to Botrytis cinerea, and improving resistance to this pathogenic fungus is a problem yet to be solved. MicroRNAs (miRNAs) play an essential role in resistance to B. cinerea, but until now, no studies have been reported concerning miRNAs induction in P. lactiflora. Here, we constructed and sequenced two small RNA (sRNA) libraries from two B. cinerea-infected P. lactiflora cultivars ("Zifengyu" and "Dafugui") with significantly different levels of resistance to B. cinerea, using the Illumina HiSeq 2000 platform. From the raw reads generated, 4,592,881 and 5,809,796 sRNAs were obtained, and 280 and 306 miRNAs were identified from "Zifengyu" and "Dafugui", respectively. A total of 237 conserved and 7 novel sequences of miRNAs were differentially expressed between the two cultivars, and we predicted and annotated their potential target genes. Subsequently, 7 differentially expressed candidate miRNAs were screened according to their target genes annotated in KEGG pathways, and the expression patterns of miRNAs and corresponding target genes were elucidated. We found that miR5254, miR165a-3p, miR3897-3p and miR6450a might be involved in the P. lactiflora response to B. cinerea infection. These results provide insight into the molecular mechanisms responsible for resistance to B. cinerea in P. lactiflora. PMID:26393656

  9. 棉团铁线莲中新葡萄糖基萘类成分%A New Glucopyranosyl Naphthalene from Clematis hexapetala Pall

    Institute of Scientific and Technical Information of China (English)

    董彩霞; 史社坡; 赵明波; 屠鹏飞

    2008-01-01

    目的:研究棉团铁线莲(Clematis hexapetala Pall.)的干燥根及根茎的化学成分.方法:利用溶剂提取、硅胶柱色谱和高效液相色谱等技术进行分离、纯化,根据理化性质和波谱数据鉴定化合物的结构.结果:从中分离得到1个葡萄糖基萘类化合物,鉴定为5,8-二氢-6-甲基萘-1,4-二-O-β-D-葡萄糖苷 (1).结论:该化合物为一新化合物,丰富了棉团铁线莲的化学成分.%AIM: To study the chemical constituents of the roots and rhizomes of Clematis hexapetala Pall.. METHODS: The solvent extraction, silica gel column chromatography and pre-HPLC were used to isolate and purify the constituent, and various spectroscopic analyses were used to elucidate the structure. RESULTS: A glucopyranosyl naphthalene (1) derivative, 5,8-dihydro-6-methyl-1,4- β- D -diglucopyranosyl naphthalene has (1) been isolated from this plant. CONCLUSION: This compound is a new one, and this study enriched the chemical constituents of Clematis hexapetala.

  10. Single-frequency, dual-GNSS versus dual-frequency, single-GNSS: a low-cost and high-grade receivers GPS-BDS RTK analysis

    Science.gov (United States)

    Odolinski, Robert; Teunissen, Peter J. G.

    2016-06-01

    The concept of single-frequency, dual-system (SF-DS) real-time kinematic (RTK) positioning has become feasible since, for instance, the Chinese BeiDou Navigation Satellite System (BDS) has become operational in the Asia-Pacific region. The goal of the present contribution is to investigate the single-epoch RTK performance of such a dual-system and compare it to a dual-frequency, single-system (DF-SS). As the SF-DS we investigate the L1 GPS + B1 BDS model, and for DF-SS we take L1, L2 GPS and B1, B2 BDS, respectively. Two different locations in the Asia-Pacific region are analysed with varying visibility of the BDS constellation, namely Perth in Australia and Dunedin in New Zealand. To emphasize the benefits of such a model we also look into using low-cost ublox single-frequency receivers and compare such SF-DS RTK performance to that of a DF-SS, based on much more expensive survey-grade receivers. In this contribution a formal and empirical analysis is given. It will be shown that with the SF-DS higher elevation cut-off angles than the conventional 10° or 15° can be used. The experiment with low-cost receivers for the SF-DS reveals (for the first time) that it has the potential to achieve comparable ambiguity resolution performance to that of a DF-SS (L1, L2 GPS), based on the survey-grade receivers.

  11. PHYSICAL REMOVAL OF CRYPTOSPORIDIUM OOCYS, E. COLI, AND BACILLUS SPORES IN DRINKING WATER: PALL CORPORATION MICROZA MICROFILTRATION 3-INCH UNIT, MODEL 4UFD40004-45; AT MANCHESTER, NEW HAMPSHIRE

    Science.gov (United States)

    Verification testing of the Pall Corporation Microza MF S;ystem equipped with a 3-inch filter module, took place between April 30 and August 9, 2000 in Manchester, NH. The source water was drawn from a canal connected to Lake Massabesic, the public reservoir that serves the Town...

  12. 棉团铁线莲总皂甘抗肿瘤作用研究%Antitumor Activities of Total Saponins from Clematis Hexapetala Pall

    Institute of Scientific and Technical Information of China (English)

    杨林; 姚广玉; 薛鸿燕; 杨明俊

    2011-01-01

    Objective:To investigate the antitumor effect of total saponins of Clematis hexapetala Pall.Methods :The total saponins from Clematis hexapetala Pall.were prepared by ethanol extraction and macroporous resin.Its anti - tumor activity in vitro and in vivo was evaluated by MTT colorimetric assay and H22 cells - bearing mice models.Results:The results showed that the total saponins of Clematis hexapetala Pall.significantly inhibited proliferation of the human hepatoma cell lines HepG2, SMMC -7721 and the human cervical carcinoma cell Hela at the concentration of 0.1 -1mg·mL-1.The IC50 value on these three tumor cells were 0.5298mg·mL-1 ,0.2047mg·mL-1 and 0.2877mg·mL-1 respectively.In vivo, high ( 1.5 g· kg - 1 ), middle ( 0.75 g· kg - 1 ) and low (0.375 g· kg - 1 ) dose total saponins of Clematis hexapetala Pall.also significantly suppressed the tumor growth with tumor inhibition rate of 41.55% ,34.96% and 32.37%respectively.The slice through the pathological observation of tumor tissue also indicated that it has good antitumor activity.However, it can also reduce the spleen index and displays certain inhibitory action to the immune organ of tumor -bearing mice.Conclusion:The total saponins from Clematis hexapetala Pall.has a significant antitumor effect, but it also can suppress immune function of experimentals animals in vivo.%目的:研究棉团铁线莲总皂苷的体内外抗肿瘤作用.方法:采用乙醇提取、大孔树脂除糖的方法制备棉团铁线莲总皂苷,以MTT法和移植性H22实体荷瘤小鼠为模型,检测不同剂量棉团铁线莲总皂苷的体内外杭肿瘤作用.结果:当质量浓度为0.1-lmg·mL-1时,其对体外培养的3株人肿瘤细胞HepG2、SMMC-7721和Hela的增值表现出显著的抑制作用,IC50依次为0.5298mg·mL-1、0.2047mg·mL-1、0.2877mg·mL-1.体内实验表明,棉团铁线莲总皂苷高(1.5g·kg-1)、中(0.75g·kg-1)、低(0.375g·kg-1) 3剂量组也较好的抑制了荷瘤小鼠瘤块

  13. 喜盐鸢尾根中化学成分的分离与结构鉴定%Isolation and structral identification of chemical constituents from Iris.halophila Pall.root

    Institute of Scientific and Technical Information of China (English)

    李小飞; 李冠; 杨博

    2013-01-01

    Four known isoflavones 5-hydroxy-6,7,4'-trimethoxy-isoflavone( Ⅰ ) ;5,7,3'-trihydroxy-6,4',5'-trime thoxy-isoflavone ( Ⅱ ) ;5,4'-dihydroxy-6,7-methylenedioxy-isoflavone ( Ⅲ) ;5-methoxy-4'-hydroxy-6,7-methylen edioxy-isoflavone(Ⅳ)were isolated from ethylacetate extract of the ethanol extract from Iris, halophila Pall. root, the structures of the four compounds were elucidated on the basis of UV,IR,MS and NMR data and correlative documents. All compounds were first isolated from Iris, halophila Pall.%从喜盐鸢尾(Iris.halophila Pall.)根乙醇提取物的乙酸乙醇提取部位中分离得到4个异黄酮类化合物,用UV、IR、MS和NMR等技术,结合文献,确定其结构为5-羟基-6,7,4′-三甲氧基异黄酮(Ⅰ);5,7,3′-三羟基-6,4′,5′-三甲氧基异黄酮(Ⅱ);5,4′-二羟基-6,7-亚甲二氧基异黄酮(Ⅲ);5-甲氧基-4′-羟基-6,7-亚甲二氧基异黄酮(Ⅳ).这四种化合物均首次从喜盐鸢尾(Iris.halophila Pall.)中分离得到.

  14. Population genetic structure and mating system in the hybrid zone between Pinus sibirica Du Tour and P. pumila (Pall. Regel at the Eastern Baikal Lake shore

    Directory of Open Access Journals (Sweden)

    E.A. Petrova

    2013-12-01

    Full Text Available Genetic structure of sympatric Pinus sibirica Du Tour and P. pumila (Pall. Regel populations and putative interspecific hybrids between them was analyzed in the Baikal Lake region (Barguzin Biosphere Natural Reserve, Davsha River basin by means of 31 allozyme loci controlling 18 enzyme systems. Several alleles at loci Adh-1, Fest-2, Lap-3, Pgi-1, Sod-3 and Skdh-1 were diagnostic for P. sibirica, while alleles typical for P. pumila were detected at loci Gdh, Got-3, Lap-3, Mdh-2, Mdh-4, Pepca, Pgi-1, Pgd-2, Pgd-3, Pgm-1 and Pgm-2. All hybrids were heterozygous for the diagnostic Skdh-2 locus. Classification into hybrids and parental species using PCA analysis of multilocus allozyme genotypes had good correspondence with diagnoses made by morphological and anatomical analyses. Approximately 27% of embryos in P. pumila seeds had P. sibirica paternal contribution, and 8% of haplotypes in effective pollen pool combined alleles typical for P. pumila and P. sibirica, and therefore were classified as pollinated by the hybrids. About 83% of embryos in seeds from the hybrids most likely originated from fertilization by P. sibirica pollen, 14% from P. pumila and 3% from hybrid trees. This result favours the view that hybrids make both male and female contributions to the reproductive output of the population and confirm the presence of backcrosses and F2 hybrids.

  15. Paeonia lactiflora Pall. protects against ANIT-induced cholestasis by activating Nrf2 via PI3K/Akt signaling pathway

    Directory of Open Access Journals (Sweden)

    Ma X

    2015-09-01

    Full Text Available Xiao Ma,1,2 Yan-ling Zhao,2 Yun Zhu,3 Zhe Chen,1,2 Jia-bo Wang,4 Rui-yu Li,1,4 Chang Chen,1,2 Shi-zhang Wei,1,2 Jian-yu Li,3 Bing Liu,5 Rui-lin Wang,3 Yong-gang Li,3 Li-fu Wang,3 Xiao-he Xiao4 1Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China; 2Department of Pharmacy, 302 Military Hospital of People’s Liberation Army, Beijing, People’s Republic of China; 3Department of Integrative Medical Center, 302 Military Hospital of People’s Liberation Army, Beijing, People’s Republic of China; 4China Military Institute of Chinese Medicine, 302 Military Hospital of People’s Liberation Army, Beijing, People’s Republic of China; 5School of Chinese Medicine, The University of Hong Kong, Hong Kong Background: Paeonia lactiflora Pall. (PLP, a traditional Chinese herbal medicine, has been used for hepatic disease treatment over thousands of years. In our previous study, PLP was shown to demonstrate therapeutic effect on hepatitis with severe cholestasis. The aim of this study was to evaluate the antioxidative effect of PLP on alpha-naphthylisothiocyanate (ANIT-induced cholestasis by activating NF-E2-related factor 2 (Nrf2 via phosphatidylinositol 3-kinase (PI3K/Akt signaling pathway. Materials and methods: Liquid chromatography-mass spectrometry (LC-MS was performed to identify the main compounds present in PLP. The mechanism of action of PLP and its therapeutic effect on cholestasis, induced by ANIT, were further investigated. Serum indices such as total bilirubin (TBIL, direct bilirubin (DBIL, aspartate aminotransferase (AST, alanine aminotransferase (ALT, alkaline phosphatase (ALP, γ-glutamyl transpeptidase (γ-GT, and total bile acid (TBA were measured, and histopathology of liver was also performed to determine the efficacy of treatment with PLP. Moreover, in order to illustrate the underlying signaling pathway, liver glutathione (GSH content and mRNA or protein levels of glutamate

  16. Digital Gene Expression Analysis to Screen Disease Resistance-Relevant Genes from Leaves of Herbaceous Peony (Paeonia lactiflora Pall. Infected by Botrytis cinerea.

    Directory of Open Access Journals (Sweden)

    Saijie Gong

    Full Text Available Herbaceous peony (Paeonia lactiflora Pall. is a well-known traditional flower in China and is widely used for landscaping and garden greening due to its high ornamental value. However, disease spots usually appear after the flowering of the plant and may result in the withering of the plant in severe cases. This study examined the disease incidence in an herbaceous peony field in the Yangzhou region, Jiangsu Province. Based on morphological characteristics and molecular data, the disease in this area was identified as a gray mold caused by Botrytis cinerea. Based on previously obtained transcriptome data, eight libraries generated from two herbaceous peony cultivars 'Zifengyu' and 'Dafugui' with different susceptibilities to the disease were then analyzed using digital gene expression profiling (DGE. Thousands of differentially expressed genes (DEGs were screened by comparing the eight samples, and these genes were annotated using the Gene ontology (GO and Kyoto encyclopedia of genes and genomes (KEGG database. The pathways related to plant-pathogen interaction, secondary metabolism synthesis and antioxidant system were concentrated, and 51, 76, and 13 disease resistance-relevant candidate genes were identified, respectively. The expression patterns of these candidate genes differed between the two cultivars: their expression of the disease-resistant cultivar 'Zifengyu' sharply increased during the early stages of infection, while it was relatively subdued in the disease-sensitive cultivar 'Dafugui'. A selection of ten candidate genes was evaluated by quantitative real-time PCR (qRT-PCR to validate the DGE data. These results revealed the transcriptional changes that took place during the interaction of herbaceous peony with B. cinerea, providing insight into the molecular mechanisms of host resistance to gray mold.

  17. Shanghai Acrobats pall on Chinese?

    Institute of Scientific and Technical Information of China (English)

    BirteZimmer

    2003-01-01

    You can feel the vibration in the air, wheneverybody is watching with tension how thesmall Chinese woman starts to climb up a swinqinq board on a desk while she is balancing a pyramid of four tablets with filled glasses ana candlesticks on her forehead. She manages this task with ease

  18. Numerical Analysis of Perturbation Forces of GPS and BDS Satellites%GPS/BDS卫星摄动力数值分析

    Institute of Scientific and Technical Information of China (English)

    宋传峰; 朱李忠; 赵忠海; 张洪文

    2016-01-01

    由精密星历利用拉格朗日插值公式求二次导数的方法计算了卫星在J2000.0惯性坐标系下的总加速度;利用现有的力模型计算了地球中心引力,地球非球形摄动力,太阳、月球和其他行星的摄动力,地球固体潮摄动力,相对论效应摄动力对GPS/BDS卫星所产生的加速度数值大小;利用G-file里的BERNE太阳光压模型参数计算了GPS卫星太阳光压摄动加速度大小;对GPS/BDS卫星所受的不同摄动力进行了数值分析,对同一摄动力对不同类型卫星的影响进行了数值分析比较。结果表明,现有力模型与GPS/BDS卫星所受的实际作用力仍有一定的差距,不同类型卫星所受摄动力有明显差异,在精密定轨的实际应用中应根据不同类型卫星建立合适的力学模型。%This paper calculated the total acceleration of the satellite in J2000.0 inertial coordinate system using the second derivative of Lagrange's interpolation formula by the precise ephemeris.Based on mechanical models, this paper computed the acceleration of GPS and BDS satellites due to the gravity of Earth's center and the perturbation forces of the Earth's non-spherical, the sun, the moon, other planets, Earth solid tide and the relativity.Using the BERNE solar pressure module parameters in G-file, this paper al-so computed the solar radiation pressure perturbation acceleration of GPS satellite.After that, we made numerical analysis and com-parison of different perturbation forces and different types of satellites.It's concluded that the difference between mechanical models and true forces of satellite is evident.It's also concluded that different types of satellite suffered significant difference in perturbation forces especially for BDS GEO satellite due to the influence of maneuver force.Therefore, in the practical application of precise orbit determination, establish a suitable mechanical model is needed.

  19. A drift line bias estimator: ARMA-based filter or calibration method, and its application in BDS/GPS-based attitude determination

    Science.gov (United States)

    Liang, Zhang; Yanqing, Hou; Jie, Wu

    2016-06-01

    The multi-antenna synchronized receiver (using a common clock) is widely applied in GNSS-based attitude determination (AD) or terrain deformations monitoring, and many other applications, since the high-accuracy single-differenced carrier phase can be used to improve the positioning or AD accuracy. Thus, the line bias (LB) parameter (fractional bias isolating) should be calibrated in the single-differenced phase equations. In the past decades, all researchers estimated the LB as a constant parameter in advance and compensated it in real time. However, the constant LB assumption is inappropriate in practical applications because of the physical length and permittivity changes of the cables, caused by the environmental temperature variation and the instability of receiver-self inner circuit transmitting delay. Considering the LB drift (or colored LB) in practical circumstances, this paper initiates a real-time estimator using auto regressive moving average-based (ARMA) prediction/whitening filter model or Moving average-based (MA) constant calibration model. In the ARMA-based filter model, four cases namely AR(1), ARMA(1, 1), AR(2) and ARMA(2, 1) are applied for the LB prediction. The real-time relative positioning model using the ARMA-based predicting LB is derived and it is theoretically proved that the positioning accuracy is better than the traditional double difference carrier phase (DDCP) model. The drifting LB is defined with a phase temperature changing rate integral function, which is a random walk process if the phase temperature changing rate is white noise, and is validated by the analysis of the AR model coefficient. The auto covariance function shows that the LB is indeed varying in time and estimating it as a constant is not safe, which is also demonstrated by the analysis on LB variation of each visible satellite during a zero and short baseline BDS/GPS experiment. Compared to the DDCP approach, in the zero-baseline experiment, the LB constant

  20. BDS thin film damage competition

    Energy Technology Data Exchange (ETDEWEB)

    Stolz, C J; Thomas, M D; Griffin, A J

    2008-10-24

    A laser damage competition was held at the 2008 Boulder Damage Symposium in order to determine the current status of thin film laser resistance within the private, academic, and government sectors. This damage competition allows a direct comparison of the current state-of-the-art of high laser resistance coatings since they are all tested using the same damage test setup and the same protocol. A normal incidence high reflector multilayer coating was selected at a wavelength of 1064 nm. The substrates were provided by the submitters. A double blind test assured sample and submitter anonymity so only a summary of the results are presented here. In addition to the laser resistance results, details of deposition processes, coating materials, and layer count will also be shared.

  1. 白血球除去フィルター(Sepacell R-500 A/Pall PL 50/100)使用による抗血小板抗体産生に及ぼす効果

    OpenAIRE

    下山, 丈人; 藤村, 吉博; 河本, 順雄; 西田, 幸世; 吉田, 英里; 水本, 保子; 八木, 秀男; 松本, 雅則; 山中, 貴世; 森井, 武志; 西川, 潔; 成田, 亘啓

    1992-01-01

    To minimize various post-transfusion complications caused by white blood cell components, Sepacell R-500 A filters (Asahi Medical) for red blood cell products and PL 50/100 filters (Pall) for platelet products to remove white blood cells were clinicallyused in a total of 46 patients with leukemia and its allied disorders, and the results were compared with those of 19 patients with whom the filters were not used. Platelet allo-antibodies, assayed by mixed passive haemagglutination (MPHA) meth...

  2. Design of GPS/BDS-based positioning and tracking system for moving targets%基于GPS/BDS的移动目标定位追踪系统设计

    Institute of Scientific and Technical Information of China (English)

    张超; 顾济华

    2015-01-01

    利用GPS(全球卫星定位系统)和BDS(北斗卫星导航系统)联合定位技术,设计了一款针对移动目标的高精度定位与跟踪系统.系统主要包括移动目标通信终端、GSM网络、GIS电子地图等.其中,核心部分——移动目标通信终端硬件由ATGM331C单元、TC35I单元和STC12C5A60S2微处理器单元等构成;其软件设计主要包括:微处理器初始化、GPS/BDS解码、短信命令解码和AT命令控制等.实践测试结果表明:该系统运行稳定,且移动目标通信终端具有定位精度高、体积小、功耗低、操作简单方便等特点,应用前景广阔.%By using the combined positioning technology of global positioning system(GPS)and BeiDou navigation satellite system(BDS),a high accuracy positioning and tracking system for moving targets was designed. The system consists of commu-nication terminal of moving target,GSM network and electronic map of GIS mainly. As the key part of the whole system,the hardware of the moving target communication terminal is composed of ATGM331C module,TC35I module and STC12C5A60S2 microprocessor. The software design includes microprocessor initialization,decoding of GPS/BDS navigation information,decoding of short message service commands and the AT command control mainly. The practical testing results indicate that the system can work steadily,and the moving target communication terminal has the characteristics of high accuracy positioning,small size,low power consumption and convenient operation. The system has a broad application prospect.

  3. Seedling emergence and salt tolerance of Suaeda physophora Pall. under salt stress%盐胁迫下囊果碱蓬出苗状况及苗期抗盐性

    Institute of Scientific and Technical Information of China (English)

    高奔; 宋杰; 刘金萍; 史功伟; 范海; 赵可夫; 王宝山

    2009-01-01

    We investigated the effect of salinity on seedling emergence, seedling growth, ion accumulation and the rate of photosynthetic oxygen evolution of Suaeda physophora Pall. The optimum salt concentration for growth of S. physophora was about 200 mmol/L NaCl. High concentrations of NaCl (400 and 600 mmol/L) did not decrease seedling emergence, while 200 mmol/L NaCl increased it. The rate of leaf photosynthetic oxygen evolution was decreased at 400 and 600 mmol/L NaCl. Maintaining a relatively high K~+/Na~+ ratio and water content in leaves under high concentrations of NaCl may be an important mechanism for the adaptation of S. physophora to high salinity.%研究了盐胁迫对囊果碱蓬出苗、幼苗生长、离子积累以及光合放氧速率的影响.囊果碱蓬生长的最适盐浓度在200 mmol/L NaCl左右.高浓度NaCl(400 mmol/L和600 mmol/L)没有显著降低其出苗率,200 mmol/L NaCl对出苗率具有促进作用.400 mmol/L和600 mmol/L NaCl显著降低了光合放氧速率.囊果碱蓬在高浓度NaCl处理下能够维持叶片较高的K~+/Na~+ 及含水量可能是其适应高盐生境的重要机制.

  4. Haridusvabadus / ajakirjast "The Freeman" tlk. Riinu Pall

    Index Scriptorium Estoniae

    2000-01-01

    Praegune haridussüsteem on vastuolus individuaalse vabaduse ja vastutuse põhimõtetega vabas ühiskonnas, hariduse kvaliteedi tõstmise asemel on süsteemis madal tase ja ebatõhus vahendite kasutamine

  5. Comparative Study Between Effects of Smilax sieboldii Miq., Clematis chinensis Osbeck.and C.hexapetala Pall.on Non-specific Immunity%粘鱼须威灵仙棉团铁线莲对非特异性免疫的影响比较

    Institute of Scientific and Technical Information of China (English)

    石强

    2011-01-01

    Objective To compare the effects of Smilax sieboldii Miq. , Clematis chinensis Osbeck. and C. hexapetala Pall, on non-specific immunity, and further determine the feasibility of Smilax sieboldii Miq. to be used as drug.Methods The carbon granules clearance test in mice and chicken red blood cell phagocytosis test were carried out to compare the effects. Results All of Smilax sieboldii Miq. , Clematis chinensis Osbeck. and C.hexapetala Pall,inhibited the phagocytic function of monocyte-macrophage and abdominal cavity macrophage in mice, and reduced non-specific immune function.Conclusion Smilax sieboldii Miq. can be used equivalently as Clematis chinensis Osbeck. for the treatment of rheumatism.%目的 比较粘鱼须、威灵仙、棉团铁线莲对非特异性免疫的影响,为粘鱼须能否作为威灵仙入药提供科学依据.方法 选择小鼠碳粒廓清法和腹腔巨噬细胞吞噬鸡红细胞法进行比较3种药物.结果 粘鱼须、威灵仙、棉团铁线莲均能抑制小鼠单核巨噬细胞和腹腔巨噬细胞的吞噬作用,降低机体非特异性免疫反应能力.结论 粘鱼须可以作为祛风湿药威灵仙使用.

  6. 粘鱼须威灵仙和棉团铁线莲对细胞免疫与体液免疫的影响比较%Comparing Study of the Effects of Smilax sieboldii Miq., Clematis chinensis Osbeck. and C. hexapetela Pall on Cellular Immunity and Humoral Immunity

    Institute of Scientific and Technical Information of China (English)

    石强

    2011-01-01

    Objective To compare the effects of Smilax sieboldii Miq. , Clematis chinensis Osbeck. and C. hexapetela Pall on cellular and humoral immunity, and further determine the feasibility of Smilax sieboldii Miq. to be used as a drug. Methods Three cellular immune indexes including the formation rate of erythrocyte rosette, amount of T cell subsets and effects on delayed type hypersensitivity; two humoral immnue ones including the number of plaque forming cell ( PFC) and amount of serum hemolysin were compared. Results All of Smilax sieboldii Miq. , Clematis chinensis Osbeck. and C. hexapetela Pall decoction were able to inhibit the activity of T-lymphocyte and reduce the humoral immune function. Conclusion Smilax sieboldii Miq. can be used equivalently as Clematis chinensis Osbeck. for the treatment of rheumatism.%目的 比较粘鱼须、威灵仙、棉团铁线莲对细胞免疫和体液免疫的影响,为粘鱼须作为威灵仙入药提供科学依据.方法 选择影响玫瑰花环形成、T细胞亚群数量、迟发型变态反应等3个细胞免疫的指标和影响抗体形成细胞数量、血清溶血素数量等2个体液免疫的指标进行比较.结果 粘鱼须、威灵仙、棉团铁线莲均能抑制T细胞功能,降低机体细胞免疫反应能力.结论 粘鱼须可以作为祛风湿药威灵仙使用.

  7. Bd/s -> mu+ mu- in ATLAS

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00215268; The ATLAS collaboration

    2016-01-01

    The ATLAS Experiment has conducted a search for the rare decays of Bs and Bd into mu+mu-. 25 fb−1 of integrated luminosity of proton-proton collisions collected during LHC Run 1 were studied and new results were obtained, as presented in this talk. An upper limit is set on the Bd to mu+mu- branching ratio of BR(Bd to mu+mu-) < 4.2×10−10 at 95% confidence level. For Bs, ATLAS measurement yields the branching ratio BR(Bs to mu+mu-)=(0.9+1.1−0.8)×10−9. The result is consistent with the Standard Model expectation and other available measurements.

  8. Bd/s -> mu+ mu- in ATLAS

    CERN Document Server

    Guenther, Jaroslav; The ATLAS collaboration

    2016-01-01

    The ATLAS Experiment has conducted a search for the rare decays of Bs and Bd into mu+mu-. 25 fb−1 of integrated luminosity of proton-proton collisions collected during LHC Run 1 were studied to provide new results presented in this talk. An upper limit is set on the branching ratio BR(Bd to mu+mu-) < 4.2×10−10 at 95% confidence level. For Bs, ATLAS measurement yields the branching ratio BR(Bs to mu+mu-)=(0.9+1.1−0.8)×10−9. The result is consistent with the Standard Model expectation and other available measurements.

  9. 新疆盐生植物猪毛菜逆向运输蛋白基因SaNHX1 3'-RACE的克隆及序列分析%Clone and Sequence Analysis of 3'RACE of Antiporter Protein Gene SaNHX1 in Xinjiang Halophytes Plant Salsola collina Pall.

    Institute of Scientific and Technical Information of China (English)

    张雨良; 罗淑萍; 杨峰山; 魏岩; 袁辉; 郭长奎

    2008-01-01

    以新疆盐生植物猪毛菜( Salsola collina Pall.)为材料提取总RNA,根据 NHX1家族同源序列保守区设计1对简并引物,进行RT-PCR扩增,得到猪毛菜逆向运输蛋白基因cDNA中间一段619 bp序列.再用快速扩增cDNA 3'末端(3' RACE)方法,得到约1 000 bp 3'末端序列.将两段序列进行拼接,得到猪毛菜长为1 585 bp(GenBank登陆号为EU072932)的逆向运输蛋白基因(SaNHX1) cDNA序列,编码370个氨基酸,其编码序列、氨基酸序列与同科耐盐植物盐角草相应序列同源性为85%和87%,研究为进一步克隆猪毛菜NHX1全基因序列和研究其功能打下基础.

  10. Shoot multiplication and plant regeneration in Caragana fruticosa (Pall.) Besser

    Institute of Scientific and Technical Information of China (English)

    ZHAI Xiao-jie; YANG Ling; SHEN Hai-long

    2011-01-01

    Different nutrient media can affectin vitro culturing protocols,and experimentation under varied growth conditions is valuable in plants where in vitro methods are in preliminary stages.We carried out the first in vitro propagation studies for the endangered species Caragana fruticosa (Fabaceae).We evaluated various nutrient media for their inpact on shoot elongation and axillary bud proliferation using different concentrations of 6-benzylaminopurine (BA) and α-naphthaleneacetic acid (NAA).Shoot elongation was evaluated based on adventitious shoot primary culture and subculture regeneration from Caragana seedlings.Our goal was to improve both micropropagation and regeneration in C.fruticosa.MS nutrient media was superior to 1/2MS macronutrients,DKW,QL,and WPM for shoot elongation and axillary shoot proliferation.Shoots grown on 1/2MS and WPM exhibited some chlorosis,and shoots on QL produced larger leavers than plants growing on normal medium.The shoot proliferation coefficient on MS media supplemented with 2.22 μM BA and 0.44 μM BA + 2.69 μM NAA was significantly higher than that with other treatments in the primary culture.Shoots on 2.22 μM BA showed a higher proliferation coefficient (3.17) than others in the subculture.Shoots were rooted on 1/2MS medium with the addition of different concentrations of NAA.The optimal concentration for rooting was 0.27 μM NAA (74%).Roots exhibited many stout and long root hairs.Survivl of established plantlets was 82% at 30 days after transfer to soil.Plants established in the green house showed normal growth and displayed no apparent morphological differences compared to stock plants.

  11. Accountability and transparency of financial sector supervision / Pall Gunnar Palsson

    Index Scriptorium Estoniae

    Palsson, Pall Gunnar

    2001-01-01

    Finantsjärelvalve üheks oluliseks tingimuseks on läbipaistvus. Rahvusvahelise Valuutafondi poolt vastu võetud raha- ja rahanduspoliitika heade tavade koodeksist. Ülevaade Islandi finantsinspektsiooni töökorraldusest

  12. Sotsiaaluuringud aitavad juhtida perepoliitikat / Kati Karelson, Katre Pall

    Index Scriptorium Estoniae

    Karelson, Kati

    2003-01-01

    Riiklikust perepoliitikast, selle tulemuste analüüs ja võrdlus teistes Euroopa riikides rakendatud institutsionaalsete meetmetega. Artikkel põhineb Euroopa Komisjoni 5. raamprogrammi projektina rahastatud ja aastail 2000-2003 korraldatud uuringu IPROSEC tulemustel. Skeemid. Tabel

  13. BDS Thin Film UV Antireflection Laser Damage Competition

    Energy Technology Data Exchange (ETDEWEB)

    Stolz, C J

    2010-10-26

    UV antireflection coatings are a challenging coating for high power laser applications as exemplified by the use of uncoated Brewster's windows in laser cavities. In order to understand the current laser resistance of UV AR coatings in the industrial and university sectors, a double blind laser damage competition was performed. The coatings have a maximum reflectance of 0.5% at 355 nm at normal incidence. Damage testing will be performed using the raster scan method with a 7.5 ns pulse length on a single testing facility to facilitate direct comparisons. In addition to the laser resistance results, details of deposition processes and coating materials will also be shared.

  14. Summary of the BDS and MDI CLIC08 Working Group

    CERN Document Server

    Tomás, R; Ahmed, I; Ambatu, PK; Angal-Kalinin, D; Barlow, R; Baud, J P; Bolzon, B; Braun, H; Burkhardt, H; Burt, GC; Corsini, R; Dalena, B; Dexter, AC; Dolgashev, V; Elsener, K; Fernandez Hernando, JL; Gaillard, G; Geffroy, N; Jackson, F; Jeremie, A; Jones, RM; McIntosh, P; Moffeit, K; Peltier, F; Resta-López, J; Rumolo, G; Schulte, D; Seryi, A; Toader, A; Zimmermann, F

    2008-01-01

    This note summarizes the presentations held within the Beam Delivery System and Machine Detector Interface working group of the CLIC08 workshop. The written contributions have been provided by the presenters on a voluntary basis.

  15. ИЗУЧЕНИЕ КОМПОНЕНТНОГО СОСТАВА ЭФИРНЫХ МАСЕЛ ЛИСТЬЕВ CRATAEGUS SANGUINEA PALL. И ТРАВЫ CONIUM MACULATUM L. ИЗ ФЛОРЫ БАШКОРТОСТАНА

    OpenAIRE

    Трофимова, С.; Булгаков, Т.; Хасанова, С.; Кудашкина, Н.

    2013-01-01

    Исследован компонентный состав полученных методом перегонки с водяным паром эфирных масел из листьев боярышника кроваво-красного Crataegus Sanguinea Pall и травы болиголова пятнистого Conium Maculatum L. методом хромато-масс-спектрометрии. В эфирном масле листьев боярышника выявлено 44 соединения, из них идентифицировано 18. В эфирном масле травы болиголова пятнистого выявлено 29 соединений, из них идентифицировано 11. Установлено, что в составе эфирных масел листьев боярышника и травы болиго...

  16. Evaluation of the Effects of Sativex (THC BDS: CBD BDS) on Inhibition of Spasticity in a Chronic Relapsing Experimental Allergic Autoimmune Encephalomyelitis: A Model of Multiple Sclerosis

    OpenAIRE

    Hilliard, A.; Stott, C.; Wright, S; Guy, G.; Pryce, G.; Al-Izki, S.; Bolton, C; Giovannoni, G.

    2012-01-01

    This study investigated the antispasticity potential of Sativex in mice. Chronic relapsing experimental allergic encephalomyelitis was induced in adult ABH mice resulting in hind limb spasticity development. Vehicle, Sativex, and baclofen (as a positive control) were injected intravenously and the “stiffness” of limbs assessed by the resistance force against hind limb flexion. Vehicle alone caused no significant change in spasticity. Baclofen (5 mg/kg) induced approximately a 40% peak reducti...

  17. Evaluation of the Effects of Sativex (THC BDS: CBD BDS) on Inhibition of Spasticity in a Chronic Relapsing Experimental Allergic Autoimmune Encephalomyelitis: A Model of Multiple Sclerosis.

    Science.gov (United States)

    Hilliard, A; Stott, C; Wright, S; Guy, G; Pryce, G; Al-Izki, S; Bolton, C; Giovannoni, G

    2012-01-01

    This study investigated the antispasticity potential of Sativex in mice. Chronic relapsing experimental allergic encephalomyelitis was induced in adult ABH mice resulting in hind limb spasticity development. Vehicle, Sativex, and baclofen (as a positive control) were injected intravenously and the "stiffness" of limbs assessed by the resistance force against hind limb flexion. Vehicle alone caused no significant change in spasticity. Baclofen (5 mg/kg) induced approximately a 40% peak reduction in spasticity. Sativex dose dependently reduced spasticity; 5 mg/kg THC + 5 mg/kg CBD induced approximately a 20% peak reduction; 10 mg/kg THC + 10 mg/kg CBD produced approximately a 40% peak reduction in spasticity. Sativex has the potential to reduce spasticity in an experimental mouse model of multiple sclerosis (MS). Baclofen reduced spasticity and served as a positive control. Sativex (10 mg/kg) was just as effective as baclofen, providing supportive evidence for Sativex use in the treatment of spasticity in MS. PMID:22928118

  18. Preventing microbial growth on pall-rings when upgrading biogas using absorption with water wash

    Energy Technology Data Exchange (ETDEWEB)

    Haakansson, Anna

    2006-07-15

    For produced biogas to be usable as vehicle fuel it has to be upgraded to a higher energy content. This is accomplished by elevation of the methane concentration through removal of carbon dioxide. Absorption with water wash is the most common upgrading method used in Sweden today. The upgrading technique is based on the fact that carbon dioxide is more soluble in water than methane. Upgrading plants that utilises this method have problems with microbial growth in the system. This growth eventually leads to a stop in operation due to the gradually drop in upgrading capacity. The aim of this thesis were to evaluate the possibility to through some kind of water treatment maintain an acceptable level of growth or altogether prevent it in order to maintain an acceptable process capacity and thereby avoid the need to clean. Through collection of literature the implementation possibilities were evaluated with regard to efficiency, economic sustainability and if there would be a release of any harmful substances. In order to prevent the microbial growth in the columns the treatment should either focus on removing microorganisms or limit the accessible nutrients. For the single pass system it is concluded that the treatment should reduce the biofilm formation and be employed in an intermittent way. Among the evaluated treatments focusing on the reduction of microorganisms the addition of peracetic acid seems to be the most promising one. For the regenerating system the treatment method could focus on either one. As for the single pass system peracetic acid could be added to reduce the amount of microorganism. To reduce the amount of organic matter an advanced oxidation process could be deployed with the advantage that it also could remove the microorganisms.

  19. Adaptation mechanisms of Coluria geoides (Pall.) Ledeb. to different ecological factors

    OpenAIRE

    Tatiana V. Leonova

    2013-01-01

    Ontogenesis of each individual occurs particularly. Polyvariation of individual development determines existence of species in various ecological-coenotic conditions, is important for adaptation and provides resistance of coenopopulations.

  20. Phenolic Compounds from Halimodendron halodendron (Pall. Voss and Their Antimicrobial and Antioxidant Activities

    Directory of Open Access Journals (Sweden)

    Jihua Wang

    2012-09-01

    Full Text Available Halimodendron halodendron has been used as forage in northwestern China for a long time. Its young leaves and flowers are edible and favored by indigenous people. In this study, eleven phenolic compounds were bioassay-guided and isolated from the aerial parts of H. halodendron for the first time. They were identified by means of physicochemical and spectrometric analysis as quercetin (1, 3,5,7,8,4'-pentahydroxy-3'-methoxy flavone (2, 3-O-methylquercetin (3, 3,3'-di-O-methylquercetin (4, 3,3'-di-O-methylquercetin-7-O-β-D-glucopyranoside (5, isorhamentin-3-O-β-D-rutinoside (6, 8-O-methylretusin (7, 8-O-methylretusin-7-O-β-D-glucopyranoside (8, salicylic acid (9, p-hydroxybenzoic acid (ferulic acid (10, and 4-hydroxy-3-methoxy cinnamic acid (11. They were sorted as flavonols (1–6, soflavones (7 and 8, and phenolic acids (9–11. Among the compounds, flanools 1–4 revealed a strong antibacterial activity with minimum inhibitory concentration (MIC values of 50–150 μg/mL, and median inhibitory concentration (IC50 values of 26.8–125.1 μg/mL. The two isoflavones (7 and 8 showed moderate inhibitory activity on the test bacteria. Three phenolic acids (9, 10 and 11 showed strong antibacterial activity with IC50 values of 28.1–149.7 μg/mL. Antifungal activities of the compounds were similar to their antibacterial activities. All these phenolic compounds showed significant antimicrobial activity with a broad spectrum as well as antioxidant activity based on 1,1-diphenyl-2-picrylhydrazyl (DPPH radical scavenging and β-carotene-linoleic acid bleaching assays. In general, the flavonol aglycones with relatively low polarity exhibited stronger activities than the glycosides. The results suggest the potential of this plant as a source of functional food ingredients and provide support data for its utilization as forage as well.

  1. Microbial Growth on Pall-rings : A problem when upgrading biogas with the technique water absorption

    OpenAIRE

    Tynell, Åsa

    2005-01-01

    Upgradering av biogas med tekniken vattenabsorption är vanligt i Sverige. Elva biogasanläggningar med tillsammans fjorton uppgraderingsanläggningar använder sig av tekniken. Problem med igensättning av fyllkroppar i absorptionskolonnen, samt i ett fall i desorptionskolonnen är vanligt förekommande och har en negativ effekt på uppgraderingen av rågas till fordonsgas. Fem av de nio anläggningarna i denna studie har problem med mikrobiell tillväxt på fyllkropparna. Syftet med denna rapport var a...

  2. Preventing Microbial Growth on pall-rings when upgrading biogas using absorption with water wash

    OpenAIRE

    Håkansson, Anna

    2006-01-01

    For produced biogas to be usable as vehicle fuel it has to be upgraded to a higher energy content. This is accomplished by elevation of the methane concentration through removal of carbon dioxide. Absorption with water wash is the most common upgrading method used in Sweden today. The upgrading technique is based on the fact that carbon dioxide is more soluble in water than methane. Upgrading plants that utilises this method have problems with microbial growth in the system. This growth event...

  3. СРАВНИТЕЛЬНАЯ МОРФОЛОГИЧЕСКАЯ ХАРАКТЕРИСТИКА СЕВРЮГИ ( АCIPENSER STELLATUS PALL.) ИЗ ПРИРОДНОЙ И АКВАКУЛЬТУРНОЙ ПОПУЛЯЦИИ

    OpenAIRE

    Шишанова, Елена; Кавтаров, Джавад

    2015-01-01

    Морфометрические исследования являются основополагающими при начале работы по одомашниванию новых видов рыб. Цель исследований сравнить морфологическую изменчивость севрюги ( Аcipenser stellatus Pall.), выращенной в условиях замкнутого водоснабжения, и природной северо-каспийской севрюги для оценки влияния индустриальных условий выращивания на ее морфотип. Впервые проведено сравнительное исследование 103 экз. половозрелой природной северо-каспийской севрюги и 50 экз. шестилеток аквакультурной...

  4. Penguin Contributions to CP Phases in B(d,s) Decays to Charmonium.

    Science.gov (United States)

    Frings, Philipp; Nierste, Ulrich; Wiebusch, Martin

    2015-08-01

    The precision of the CP phases 2β and 2β(s) determined from the mixing-induced CP asymmetries in B(d)→J/ψK(S) and B(s)→J/ψϕ, respectively, is limited by the unknown long-distance contribution of a penguin diagram involving up quarks. The penguin contribution is expected to be comparable in size to the precision of the LHCb and Belle II experiments and, therefore, limits the sensitivity of the measured quantities to new physics. We analyze the infrared QCD structure of this contribution and find that all soft and collinear divergences either cancel between different diagrams or factorize into matrix elements of local four-quark operators up to terms suppressed by Λ(QCD)/m(ψ), where m(ψ) denotes the J/ψ mass. Our results, which are based on an operator product expansion, allow us to calculate the penguin-to-tree ratio P/T in terms of the matrix elements of these operators and to constrain the penguin contribution to the phase 2β as |Δϕ(d)|≤0.68°. The penguin contribution to 2β(s) is bounded as |Δϕ(s)(0)|≤0.97°, |Δϕ(s)(∥)|≤1.22°, and |Δϕ(s)(⊥)|≤0.99° for the case of longitudinal, parallel, and perpendicular ϕ and J/ψ polarizations, respectively. Further, we place bounds on |Δϕ(d)| for B(d)→ψ(2S)K(S) and the polarization amplitudes in B(d)→J/ψK(*). In our approach, it is further possible to constrain P/T for decays in which P/T is Cabibbo unsuppressed, and we derive upper limits on the penguin contribution to the mixing-induced CP asymmetries in B(d)→J/ψπ(0), B(d)→J/ψρ(0), B(s)→J/ψK(S), and B(s)→J/ψK(*). For all studied decay modes, we also constrain the sizes of the direct CP asymmetries. PMID:26296109

  5. Study of the decays B->D_s1(2536)+ anti-D(*)

    OpenAIRE

    Aushev, T.

    2011-01-01

    We report a study of the decays B -> D_s1(2536)+ anti-D(*), where anti-D(*) is anti-D0, D- or D*-, using a sample of 657 x 10^6 B anti-B pairs collected at the Upsilon(4S) resonance with the Belle detector at the KEKB asymmetric-energy e+e- collider. The branching fractions of the decays B+ -> D_s1(2536)+ anti-D0, B0 -> D_s1(2536)+ D- and B0 -> D_s1(2536)+ D*- multiplied by that of D_s1(2536)+ -> (D*0K+ + D*+K0) are found to be (3.97+-0.85+-0.56) x 10^-4, (2.75+-0.62+-0.36) x 10^-4 and (5.01+...

  6. Study of Pure Annihilation Decays B_{d,s} \\to D^{0} \\bar D^{0}

    CERN Document Server

    Li, Ying

    2007-01-01

    With heavy quark limit and hierarchy approximation $\\lambda_{QCD}\\ll m_D\\ll m_B$, we analyze the $B\\to D^0\\bar D^0$ and $B_s\\to D^0\\bar D^0$ decays, which occur purely via annihilation type diagrams. As a roughly estimation, we calculate their branching ratios and CP asymmetries in Perturbative QCD approach. The branching ratio of $B\\to D^0\\bar D^0$ is about $3.8\\times10^{-5}$ that is just below the latest experimental upper limit. The branching ratio of $B_s\\to D^0\\bar D^0$ is about $6.8\\times10^{-4}$, which could be measured in LHC-b. From the calculation, it could be found that this branching ratio is not sensitive to the weak phase angle $\\gamma$. In these two decay modes, there exist CP asymmetries because of interference between weak and strong interaction. However, these asymmetries are too small to be measured easily.

  7. Effect of Calcium Sprays on Mechanical Strength and Cell Wall Fractions of Herbaceous Peony (Paeonia Lactiflora Pall. Inflorescence Stems

    Directory of Open Access Journals (Sweden)

    Jintao Ge

    2012-04-01

    Full Text Available Calcium is an essential element and imparts significant structural rigidity to the plant cell walls, which provide the main mechanical support to the entire plant. In order to increase the mechanical strength of the inflorescence stems of herbaceous peony, the stems are treated with calcium chloride. The results shows that preharvest sprays with 4% (w/v calcium chloride three times after bud emergence are the best at strengthening “Da Fugui” peonies’ stems. Calcium sprays increased the concentrations of endogenous calcium, total pectin content as well as cell wall fractions in herbaceous peonies stems, and significantly increased the contents of them in the top segment. Correlation analysis showed that the breaking force of the top segment of peonies’ stems was positively correlated with the ratio of water insoluble pectin to water soluble pectin (R = 0.673 as well as lignin contents (R = 0.926 after calcium applications.

  8. Edgar Allan Poe’s "The Pall of the House of Usher" - the Theme of the Physical Power of Words

    OpenAIRE

    Maszewski, Zbigniew

    1987-01-01

    Zadanie pt. „Digitalizacja i udostępnienie w Cyfrowym Repozytorium Uniwersytetu Łódzkiego kolekcji czasopism naukowych wydawanych przez Uniwersytet Łódzki” nr 885/P-DUN/2014 dofinansowane zostało ze środków MNiSW w ramach działalności upowszechniającej naukę

  9. The invasion history, distribution and colour pattern forms of the harlequin ladybird beetle Harmonia axyridis (Pall. (Coleoptera, Coccinellidae in Slovakia, Central Europe

    Directory of Open Access Journals (Sweden)

    Ľubomír Panigaj

    2014-05-01

    Full Text Available The harlequin ladybird beetle Harmonia axyridis (Coleoptera, Coccinellidae has invaded and established in Slovakia. Following unintentional introduction in 2008, the spread of the alien coccinellid was very fast. By the end of 2009, it was recorded across the whole country, and by the end of 2012 it was widely distributed and common in various habitats, particularly gardens, orchards and urban areas, where it was most frequent on trees. The rate of eastward spread was approximately 200 km year-1, similar to the overall rate of spread in Europe. Between 2008 and 2012, the coccinellid was recorded in a total of 153 localities, in altitudes ranging from 98 to 1,250 m. Most records of this species were made in lowlands, hilly areas and valleys separating mountain ridges. However, it was only rarely documented in areas above 700 m a.s.l. The non-melanic colour form (f. succinea was dominant along alongitudinal transect including eight urban areas across Slovakia, with the frequency of melanic forms (f. spectabilis and f. conspicua together between 6.3 and 19.2% and a median equal to 10.5%. The invasion history and distribution of H. axyridis in Slovakia are discussed with regard to the time sequence of records, rate of spread, altitudinal distribution, anthropogenic dispersal, effective recording, proportion of melanic forms and other relevant aspects associated with the spread of this successful invader.

  10. The comparative characteristic of sensitivity of daphnia (Daphnia magna Str.) and hydra (Hydra attenuata Pall.) to the action of Pb and Cd ions

    International Nuclear Information System (INIS)

    The influence of lead and cadmium ions on Daphnia magna and Hydra attenuata in acute experiments is investigated. Toxicants' influence caused a mortality of Daphnia magna and morphological changes in Hydra attenuata. The toxic influence of cadmium was revealed greater than that of lead. A level of the toxic effect is directly proportional to the concentration and time of toxicants' actions. In comparison with Hydra attenuata, the toxic effect on Daphnia magna is revealed much earlier, which testifies to their greater sensitivity

  11. The invasion history, distribution and colour pattern forms of the harlequin ladybird beetle Harmonia axyridis (Pall.) (Coleoptera, Coccinellidae) in Slovakia, Central Europe

    Czech Academy of Sciences Publication Activity Database

    Panigaj, L.; Zach, P.; Honěk, A.; Nedvěd, Oldřich; Kulfan, J.; Martínková, Z.; Selyemová, D.; Viglášová, S.; Roy, H. E.

    -, č. 412 (2014), s. 89-102. ISSN 1313-2989 Grant ostatní: Slovak Research and Development Agency(SK) APVV 0200/11; Grant Agency of Ministry of Education and SAS(SK) 1/1025/12; Grant Agency of Ministry of Education and SAS(SK) 2/0035/13; Grant Agency of Ministry of Education and SAS(SK) 2/0157/11; Mze ČR(CZ) QH82047; MŠMT ČR(CZ) 7AMB12SK141; EU COST(CZ) TD1209 Institutional support: RVO:60077344 Keywords : alien * altitude * colour morphs Subject RIV: EH - Ecology, Behaviour Impact factor: 0.933, year: 2014 http://europepmc.org/articles/PMC4042697;jsessionid=aEQnuIZkqJpBc2xpenqy.0

  12. Muusikamaailm : CPE Bachi käsikirjad tagasi Saksamaale. Täna uusooper Londonis. Theodorakise ooperid plaadil. David Golub lahkunud. Preemia Palle Mikkelborgile / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2001-01-01

    Ukraina nõustus tagastama Saksamaale C.P.E. Bachi muusikakäsikirjad, mis Nõukogude Liidu armee sealt II Maailmasõja ajal ära viis. Inglise Rahvusooperis lavastuvast D.Saweri ooperist "From Morning to Midnight". M.Theodorakise kolm ooperit (antiiktriloogia "Elektra", "Antigone" ja "Medeia") ilmusid seoses maestro 75. juubeliga kaheksal CD-plaadil. Lühidalt D.Golubist. Põhjamaade Nõukogu tänavuse muusikapreemia võitis P.Mikkelborg

  13. Evaluation of tooth preparations for Class II cavities using magnification loupes among dental interns and final year BDS students in preclinical laboratory

    Directory of Open Access Journals (Sweden)

    Khyati Narula

    2015-01-01

    Conclusions: Magnifying loupes help the dental students to have better vision, thus improved dexterity with hands while preparing the tooth for restoration. However, dental students have to get adapted to the loupes for the ease of using loupes. Using loupes frequently may help them to get adapted to the loupes.

  14. Electric energy forecast by using Arma, Nara, Polynomial and Pall models: a comparative study; Predicao de demanda de energia eletrica utilizando modelos Arma, Narma, polinomial e PLL: um estudo comparativo

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Viviane Cota; Furtado, Edgar Campos; Aguirre, Luiz Antonio [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Programa de Pos-Graduacao em Engenharia Eletrica (PGEE)]. E-mails: vivianne@cpdee.ufmg.br; edgar@cpdee.ufmg.br; aguirre@cpdee.ufmg.br; Correa, Marcelo Vieira [Centro Universitario do Leste de Minas Gerais, Coronel Fabriciano, MG (Brazil)]. E-mail: mcorrea@unilestemg.br

    2004-07-01

    This work presents a case study for the short term electric power demand prediction testing three types of mathematical models: the Aroma, the polynomial Nara, and the Local Linear Predictor - Lp already used in other case studies, with time schedule established for the prediction as 8 hours ahead. The work is stimulated by the need to obtain good predictors for the electric energy demand, as the short term load prediction is very important for the electric power enterprises. The results obtained with the studying data demonstrate most suitability of the Nam polynomial model when compared to the LLP model in the prediction of electric energy demand.

  15. Full sun-spay-cutting method of Rosa Davurica Pall ' twig cutting%全光雾喷法在刺玫果嫩枝扦插上的应用

    Institute of Scientific and Technical Information of China (English)

    周军方; 段进潮; 徐岩; 任跃英; 王远亮; 肖兴利; 王秀萍

    2011-01-01

    全光雾喷法扦插育苗是近几年应用较多的快速育苗技术,它具有生根快、繁殖率高的特点,是快速繁殖优良品种苗木的一条重要途径。笔者对刺玫果分别用普通扦插和全光雾喷法进行夏季嫩枝扦插试验,结果表明用浓度为2×10-5g/mL的IBA浸泡16小时处理的插穗使用全光雾插法生根率可高达96%。%Full sun-spay-cutting method is the most applied on rapid seedling technique in recent years, its characteristic takes root quickly and reproductive rate high. It is important way of good varieties 'rapid propagation. By using chemical treatments of IBA on twig cuttings under common cutting and the full sun-spay-cutting method for summer cuttings test .The results show that adopted full sun-spay-eutting method ,which was cutting stems in summer, dousing in 2×10-5g/mL IBA for 16 hours .The rooting rate could reach 96%.

  16. Extraction and Separation of Vitisin D, Ampelopsin B and cis-Vitisin A from Iris lactea Pall. var. chinensis (Fisch.) Koidz by Alkaline Extraction-Acid Precipitation and High-Speed Counter-Current Chromatography.

    Science.gov (United States)

    Lv, Huanhuan; Zhou, Wenna; Wang, Xiaoyan; Wang, Zhenhua; Suo, Yourui; Wang, Honglun

    2016-01-01

    Naturally occurring oligostilbenes are receiving more attention because they exhibit several beneficial effects for health, including hepatoprotective, antitumor, anti-adipogenic, antioxidant, antiaging, anti-inflammatory, anti-microbial, antiviral, immunosuppressive and neuroprotective activities. Thus, they could be of some potentially therapeutic values for several diseases. In this study, we adopted the alkaline extraction-acid precipitation (AEAP) method for extraction of oligostilbenes from the seed kernel of Iris lactea Then, the high-speed counter-current chromatography (HSCCC) was used for preparative isolation and purification of oligostilbenes from the AEAP extracts. Finally, three oligostilbenes, namely vitisin D (73 mg), ampelopsin B (25 mg) and cis-vitisin A (16 mg), were successfully fractionated by HSCCC with a two-phase solvent system composed of n-hexane-ethyl acetate-methanol-water (2:5:3:6, v/v/v/v) from 300 mg of the AEAP extracts in ∼ 190 min. The purities of the three isolated oligostilbenes were all over 95.0% as analyzed by high performance liquid chromatography. They all were isolated from I. lacteal for the first time.The method of AEAP for the preparation of the oligostilbene-enriched crude sample was simple, and the HSCCC technique for the isolation and purification of oligostilbenes was efficient. PMID:26847919

  17. 白芍多糖的制备、理化性质及抗肿瘤活性研究%Studies on Preparation, Physicochemical Properties and Antitumor Activity of Polysaccharide from the Root of Paeonia lactiflora Pall.

    Institute of Scientific and Technical Information of China (English)

    汪芸; 陶移文; 田庚元

    2013-01-01

    目的:研究中药白芍中多糖的制备、理化性质及对小鼠路易斯肺癌和S180肉瘤的抗肿瘤活性.方法:采用水提醇沉方法提取白芍中多糖(BSEP),测定其糖和糖醛酸含量、元素组成、单糖组成;同时采用小鼠路易斯肺癌足趾皮下接种模型和S180肉瘤腋皮下接种模型考察BSEP的抗肿瘤活性.结果:BSEP的提取率分别为1.56%,糖含量为80.56%,糖醛酸含量为3.33%,单糖组成分析为91.7%的葡萄糖,4.19%的半乳糖以及2.83%的阿拉伯糖.生物活性表明BSEP样品分别以200,100mg·kg-1剂量ip×10qd的治疗方案,对小鼠体内路易斯肺癌足趾接种模型的肿瘤抑制率分别为54.58%和43.33%,对小鼠S180肉瘤皮下接种模型的肿瘤抑制率分别为47.08%和38.98%.结论:BSEP是主要以葡萄糖组成,且含有少量糖醛酸的多糖,具有一定的抗肿瘤活性,对小鼠路易斯肺癌的疗效稍优于S180肉瘤模型.

  18. Muğla-Fethiye Yöresinde Doğal Yayılış Yapan Crataegus orientalis Pall. ex M.Bieb. Taksonlarının Uçucu Bileşenlerinin Belirlenmesi

    Directory of Open Access Journals (Sweden)

    Sevgin ÖZDERİN

    2015-03-01

    Full Text Available In this study, volatile components of C. orientalis subsp. orientalis and C. orientalis subsp. szovitsii which are belonging an important howthorn taxa for Turkey, was determined. Leaf and flower samples of plant taxa were collected from Muğla-Fethiye in 2012 and dried in room temperature for determining to volatile contents of howthorn taxa and these contents were determined by GC-MS As result of analyses, totally 53 volatile components belonging to C. orientalis subsp. orientalis and C. orientalis subsp. szovitsii taxa were determined. According to GC-MS results, most effective components were determined as 2-Hexenal (38,55%, 3-Hexenol (13,98%, Capronaldehyde (6,81% for C. orientalis subsp. orientalis and Propyl methyl ketone (26.60%, Butyraldehyde(9,37%, 2-Hexenal (6,55% in case C. orientalis subsp. szovitsii

  19. Leachables evaluation for bulk drug substance.

    Science.gov (United States)

    Tsui, Victor; Somma, Maria S; Zitzner, Linda A

    2009-01-01

    This study describes a comprehensive analytical approach for evaluating potential leachables from product-contacting material surfaces in the manufacture of bulk drug substance (BDS) for use in parenteral products. A qualitative step-by-step evaluation of the process stream for the production, purification, and storage of the BDS was performed. The product-contact equipment surfaces were then grouped based on their materials of construction and prioritized according to the potential risk of contributing leachables to the BDS. Based on this evaluation, 13 potential leachable species were identified and classified either as volatile organic compounds (VOCs), semi-volatile organic compounds (SVOCs), anions, cations, or trace metals. The BDS was first screened for the presence of VOCs, SVOCs, anions, cations, and trace metals using analytical methods that were qualified for their application with the BDS. Thirteen potential leachables were then spiked in the BDS and in the water for injection for spike-recovery studies. The analysis of the BDS for potential leachables showed that the potential impurities were not present in the BDS except for a trace amount of silicon, and that the residual solvent concentrations were lower than the recommended limits established by the International Committee on Harmonisation. The spike-recovery studies confirmed that the analytical methods could effectively determine the leachable compounds in the BDS. Moreover, the 13 contaminants did not form a complex with the protein in the BDS and did not represent a potential risk to the BDS's safety and stability. PMID:19634355

  20. Papers

    DEFF Research Database (Denmark)

    Thoft-Christensen, Palle

    The chapters in this Volume 7 of a series of PAPERS are based on papers published in the period 2004 - 2008 authored/co-authored by Palle Thoft-Christensen......The chapters in this Volume 7 of a series of PAPERS are based on papers published in the period 2004 - 2008 authored/co-authored by Palle Thoft-Christensen...

  1. Assessment of the Contribution of BeiDou GEO, IGSO, and MEO Satellites to PPP in Asia—Pacific Region

    Directory of Open Access Journals (Sweden)

    Qile Zhao

    2015-12-01

    Full Text Available In contrast to the US Global Positioning System (GPS, the Russian Global Navigation Satellite System (GLONASS and the European Galileo, the developing Chinese BeiDou satellite navigation system (BDS consists of not only Medium Earth Orbit (MEO, but also Geostationary Orbit (GEO as well as Inclined Geosynchronous Orbit (IGSO satellites. In this study, the Precise Point Positioning (PPP and PPP with Integer Ambiguity Resolution (IAR are obtained. The contributions of these three different types of BDS satellites to PPP in Asia-Pacific region are assessed using data from selected 20 sites over more than four weeks. By using various PPP cases with different satellite combinations, in general, the largest contribution of BDS IGSO among the three kinds of BDS satellites to the reduction of convergence time and the improvement of positioning accuracy, particularly in the east direction, is identified. These PPP cases include static BDS only solutions and static/kinematic ambiguity-float and -fixed PPP with the combination of GPS and BDS. The statistical results demonstrate that the inclusion of BDS GEO and MEO satellites can improve the observation condition and result in better PPP performance as well. When combined with GPS, the contribution of BDS to the reduction of convergence time is, however, not as significant as that of GLONASS. As far as the positioning accuracy is concerned, GLONASS improves the accuracy in vertical component more than BDS does, whereas similar improvement in horizontal component can be achieved by inclusion of BDS IGSO and MEO as GLONASS.

  2. Assessment of the Contribution of BeiDou GEO, IGSO, and MEO Satellites to PPP in Asia–Pacific Region

    Science.gov (United States)

    Zhao, Qile; Wang, Chen; Guo, Jing; Liu, Xianglin

    2015-01-01

    In contrast to the US Global Positioning System (GPS), the Russian Global Navigation Satellite System (GLONASS) and the European Galileo, the developing Chinese BeiDou satellite navigation system (BDS) consists of not only Medium Earth Orbit (MEO), but also Geostationary Orbit (GEO) as well as Inclined Geosynchronous Orbit (IGSO) satellites. In this study, the Precise Point Positioning (PPP) and PPP with Integer Ambiguity Resolution (IAR) are obtained. The contributions of these three different types of BDS satellites to PPP in Asia–Pacific region are assessed using data from selected 20 sites over more than four weeks. By using various PPP cases with different satellite combinations, in general, the largest contribution of BDS IGSO among the three kinds of BDS satellites to the reduction of convergence time and the improvement of positioning accuracy, particularly in the east direction, is identified. These PPP cases include static BDS only solutions and static/kinematic ambiguity-float and -fixed PPP with the combination of GPS and BDS. The statistical results demonstrate that the inclusion of BDS GEO and MEO satellites can improve the observation condition and result in better PPP performance as well. When combined with GPS, the contribution of BDS to the reduction of convergence time is, however, not as significant as that of GLONASS. As far as the positioning accuracy is concerned, GLONASS improves the accuracy in vertical component more than BDS does, whereas similar improvement in horizontal component can be achieved by inclusion of BDS IGSO and MEO as GLONASS. PMID:26633406

  3. Assessment of BeiDou differential code bias variations from multi-GNSS network observations

    Science.gov (United States)

    Jin, S. G.; Jin, R.; Li, D.

    2016-02-01

    The differential code bias (DCB) of global navigation satellite systems (GNSSs) affects precise ionospheric modeling and applications. In this paper, daily DCBs of the BeiDou Navigation Satellite System (BDS) are estimated and investigated from 2-year multi-GNSS network observations (2013-2014) based on global ionospheric maps (GIMs) from the Center for Orbit Determination in Europe (CODE), which are compared with Global Positioning System (GPS) results. The DCB of BDS satellites is a little less stable than GPS solutions, especially for geostationary Earth orbit (GEO) satellites. The BDS GEO observations decrease the precision of inclined geosynchronous satellite orbit (IGSO) and medium Earth orbit (MEO) DCB estimations. The RMS of BDS satellites DCB decreases to about 0.2 ns when we remove BDS GEO observations. Zero-mean condition effects are not the dominant factor for the higher RMS of BDS satellites DCB. Although there are no obvious secular variations in the DCB time series, sub-nanosecond variations are visible for both BDS and GPS satellites DCBs during 2013-2014. For satellites in the same orbital plane, their DCB variations have similar characteristics. In addition, variations in receivers DCB in the same region are found with a similar pattern between BDS and GPS. These variations in both GPS and BDS DCBs are mainly related to the estimated error from ionospheric variability, while the BDS DCB intrinsic variation is in sub-nanoseconds.

  4. Hi-C Observations of Sunspot Penumbral Bright Dots

    CERN Document Server

    Alpert, Shane E; Moore, Ronald L; Winebarger, Amy R; Savage, Sabrina L

    2016-01-01

    We report observations of bright dots (BDs) in a sunspot penumbra using High Resolution Coronal Imager (Hi-C) data in 193 \\AA\\ and examine their sizes, lifetimes, speeds, and intensities. The sizes of the BDs are on the order of 1\\arcsec\\ and are therefore hard to identify in the Atmospheric Imaging Assembly (AIA) 193 \\AA\\ images, which have 1.2\\arcsec\\ spatial resolution, but become readily apparent with Hi-C's five times better spatial resolution. We supplement Hi-C data with data from AIA's 193 \\AA\\ passband to see the complete lifetime of the BDs that appeared before and/or lasted longer than Hi-C's 3-minute observation period. Most Hi-C BDs show clear lateral movement along penumbral striations, toward or away from the sunspot umbra. Single BDs often interact with other BDs, combining to fade away or brighten. The BDs that do not interact with other BDs tend to have smaller displacements. These BDs are about as numerous but move slower on average than Interface Region Imaging Spectrograph (IRIS) BDs, rec...

  5. Ambiguity resolved precise point positioning with GPS and BeiDou

    Science.gov (United States)

    Pan, Li; Xiaohong, Zhang; Fei, Guo

    2016-07-01

    This paper focuses on the contribution of the global positioning system (GPS) and BeiDou navigation satellite system (BDS) observations to precise point positioning (PPP) ambiguity resolution (AR). A GPS + BDS fractional cycle bias (FCB) estimation method and a PPP AR model were developed using integrated GPS and BDS observations. For FCB estimation, the GPS + BDS combined PPP float solutions of the globally distributed IGS MGEX were first performed. When integrating GPS observations, the BDS ambiguities can be precisely estimated with less than four tracked BDS satellites. The FCBs of both GPS and BDS satellites can then be estimated from these precise ambiguities. For the GPS + BDS combined AR, one GPS and one BDS IGSO or MEO satellite were first chosen as the reference satellite for GPS and BDS, respectively, to form inner-system single-differenced ambiguities. The single-differenced GPS and BDS ambiguities were then fused by partial ambiguity resolution to increase the possibility of fixing a subset of decorrelated ambiguities with high confidence. To verify the correctness of the FCB estimation and the effectiveness of the GPS + BDS PPP AR, data recorded from about 75 IGS MGEX stations during the period of DOY 123-151 (May 3 to May 31) in 2015 were used for validation. Data were processed with three strategies: BDS-only AR, GPS-only AR and GPS + BDS AR. Numerous experimental results show that the time to first fix (TTFF) is longer than 6 h for the BDS AR in general and that the fixing rate is usually less than 35 % for both static and kinematic PPP. An average TTFF of 21.7 min and 33.6 min together with a fixing rate of 98.6 and 97.0 % in static and kinematic PPP, respectively, can be achieved for GPS-only ambiguity fixing. For the combined GPS + BDS AR, the average TTFF can be shortened to 16.9 min and 24.6 min and the fixing rate can be increased to 99.5 and 99.0 % in static and kinematic PPP, respectively. Results also show that GPS + BDS PPP AR outperforms

  6. Optimization of low sulfur carob pulp liquor as carbon source for fossil fuels biodesulfurization

    OpenAIRE

    Silva, Tiago P.; Paixão, Susana M.; Teixeira, A. V.; Roseiro, J. Carlos; Alves, Luís Manuel

    2013-01-01

    Background:Biodesulfurization (BDS) is a complementary technology to hydrodesulfurization since it allows the removal of recalcitrant sulfur compounds present in fossil fuels. The cost of culture medium to produce the biocatalysts is still one limitation for BDS application. Carob pulp, as an alternative carbon source, can reduce this cost. However, the presence of sulfates is critical, since BDS is inhibited at very low concentrations. Thus, the goal of this work was to optimize the process ...

  7. Real-time retrieval of precipitable water vapor from GPS and BeiDou observations

    Science.gov (United States)

    Lu, Cuixian; Li, Xingxing; Nilsson, Tobias; Ning, Tong; Heinkelmann, Robert; Ge, Maorong; Glaser, Susanne; Schuh, Harald

    2015-09-01

    The rapid development of the Chinese BeiDou Navigation Satellite System (BDS) brings a promising prospect for the real-time retrieval of zenith tropospheric delays (ZTD) and precipitable water vapor (PWV), which is of great benefit for supporting the time-critical meteorological applications such as nowcasting or severe weather event monitoring. In this study, we develop a real-time ZTD/PWV processing method based on Global Positioning System (GPS) and BDS observations. The performance of ZTD and PWV derived from BDS observations using real-time precise point positioning (PPP) technique is carefully investigated. The contribution of combining BDS and GPS for ZTD/PWV retrieving is evaluated as well. GPS and BDS observations of a half-year period for 40 globally distributed stations from the International GNSS Service Multi-GNSS Experiment and BeiDou Experiment Tracking Network are processed. The results show that the real-time BDS-only ZTD series agree well with the GPS-only ZTD series in general: the RMS values are about 11-16 mm (about 2-3 mm in PWV). Furthermore, the real-time ZTD derived from GPS-only, BDS-only, and GPS/BDS combined solutions are compared with those derived from the Very Long Baseline Interferometry. The comparisons show that the BDS can contribute to real-time meteorological applications, slightly less accurately than GPS. More accurate and reliable water vapor estimates, about 1.3-1.8 mm in PWV, can be obtained if the BDS observations are combined with the GPS observations in the real-time PPP data processing. The PWV comparisons with radiosondes further confirm the performance of BDS-derived real-time PWV and the benefit of adding BDS to standard GPS processing.

  8. Exploring the Mechanism of Biocatalyst Inhibition in Microbial Desulfurization

    OpenAIRE

    Abin-Fuentes, Andres; Mohamed, Magdy El-Said; Wang, Daniel I. C.; Kristala L. J. Prather

    2013-01-01

    Microbial desulfurization, or biodesulfurization (BDS), of fuels is a promising technology because it can desulfurize compounds that are recalcitrant to the current standard technology in the oil industry. One of the obstacles to the commercialization of BDS is the reduction in biocatalyst activity concomitant with the accumulation of the end product, 2-hydroxybiphenyl (HBP), during the process. BDS experiments were performed by incubating Rhodococcus erythropolis IGTS8 resting-cell suspensio...

  9. Evaluation of the efficiency of biofield diagnostic system in breast cancer detection using clinical study results and classifiers.

    Science.gov (United States)

    Subbhuraam, Vinitha Sree; Ng, E Y K; Kaw, G; Acharya U, Rajendra; Chong, B K

    2012-02-01

    The division of breast cancer cells results in regions of electrical depolarisation within the breast. These regions extend to the skin surface from where diagnostic information can be obtained through measurements of the skin surface electropotentials using sensors. This technique is used by the Biofield Diagnostic System (BDS) to detect the presence of malignancy. This paper evaluates the efficiency of BDS in breast cancer detection and also evaluates the use of classifiers for improving the accuracy of BDS. 182 women scheduled for either mammography or ultrasound or both tests participated in the BDS clinical study conducted at Tan Tock Seng hospital, Singapore. Using the BDS index obtained from the BDS examination and the level of suspicion score obtained from mammography/ultrasound results, the final BDS result was deciphered. BDS demonstrated high values for sensitivity (96.23%), specificity (93.80%), and accuracy (94.51%). Also, we have studied the performance of five supervised learning based classifiers (back propagation network, probabilistic neural network, linear discriminant analysis, support vector machines, and a fuzzy classifier), by feeding selected features from the collected dataset. The clinical study results show that BDS can help physicians to differentiate benign and malignant breast lesions, and thereby, aid in making better biopsy recommendations. PMID:20703753

  10. Business training markets for small enterprises in developing countries : what do we know so far about the potential?

    OpenAIRE

    Suzuki, Akiko

    2002-01-01

    Examines potential markets for "private training" or training services offered on a commercial basis. Discusses the role that private sector actors can play through Business Development Services (BDS).

  11. Uikala prügila sai puhastusseadmed / Külli Kriis

    Index Scriptorium Estoniae

    Kriis, Külli, 1961-

    2004-01-01

    Ilmunud ka: Severnoje Poberezhje, 22. mai 2004, lk. 3. 21. mail 2004 Ida-Virumaal Uikala prügilas avatud puhastusseadmete kompleksist, mille valmistas ja paigaldas rahvusvaheline ettevõte Pall Corporation

  12. Endotoxin removal by end-line filters.

    OpenAIRE

    Vanhaecke, E; De Muynck, C; Remon, J P; Colardyn, F

    1989-01-01

    Four commonly used end-line filters, one with a charge-modified hydrophilic nylon filter (ELD96; Pall Biomedical Ltd., Portsmouth, United Kingdom), one with an unmodified nylon filter (FAE020; Pall Biomedical), and two with hydrophilic cellulose ester filters (Ivex-HP, Millipore Corp., Bedford, Mass.; Sterifix, Braun-Gelman, Brussels, Belgium), were evaluated for their endotoxin-removing capacity in saline and 5% glucose. Natural endotoxins derived from Escherichia coli 8739 and the lipopolys...

  13. Data mining approach to evaluating the use of skin surface electropotentials for breast cancer detection.

    Science.gov (United States)

    Sree, S Vinitha; Ng, E Y K; Acharya, U Rajendra

    2010-02-01

    The Biofield Diagnostic System (BDS) uses a score formed with measured skin surface electropotentials and a prior Level Of Suspicion (LOS) value (predicted by the physician based on the patient's ultrasound or mammography results) to calculate a revised Post-BDS LOS to indicate the presence of breast cancer. The demographic details, BDS test results, and the recorded electropotential values form a potentially useful dataset, which can be further explored with data mining tools to extract important information that can be used to improve the current predictive accuracy of the device. According to the proposed data mining framework, the BDS dataset with 291 cases was first pre-processed to remove outliers and then used to select relevant and informative features for classifier development and finally to evaluate the capability of the built classifiers in detecting the presence of the disease. Two popular feature selection techniques, namely, the filter and wrapper methods, were used in parallel for feature selection. A few statistical inference based classifiers and neural networks were used for classification. The proposed technique significantly improved the BDS prediction accuracy. Also, the use of prior LOS and, hence, the Post-BDS LOS, associates a mild subjective interpretation to the current prediction methodology used by BDS. However, the feature subset selected in our analysis that gave the best accuracy did not use either of these features. This result indicates the possibility of using BDS as a better objective assessment tool for breast cancer detection. PMID:20082535

  14. The Prevalence of Middle Eastern Extremist Ideologies among Some Canadian Offenders

    Science.gov (United States)

    Loza, Wagdy

    2010-01-01

    The Belief Diversity Scale (BDS) was administered to 89 male Canadian offenders of different religious backgrounds. The BDS is a 33-item, six-subscale instrument designed to quantitatively measure the religious attitudes, beliefs, and ideologies of Middle Eastern extremists on risk areas described in the literature. Results indicated that the…

  15. Bromodomain and extra-terminal (BET) family proteins: New therapeutic targets in major diseases

    Indian Academy of Sciences (India)

    Balasundaram Padmanabhan; Shruti Mathur; Manjula Ramu; Shailesh Tripathi

    2016-06-01

    The bromodomains and extra-terminal domain (BET) family proteins recognize acetylated chromatin through their bromodomains (BDs) and helps in regulating gene expression. BDs are chromatin ‘readers’; by interacting with acetylated lysines on the histone tails, they recruit chromatin-regulating proteins on the promoter region to regulate gene expression and repression. Extensive efforts have been employed by the scientific communities worldwide, to identify and develop potential inhibitors of BET family BDs to regulate protein expression by inhibiting acetylated histone (H3/H4) interactions. Several small molecule inhibitors have been reported, which not only have high affinity, but also have high specificity to BET BDs. These developments make BET family proteins to be an important therapeutic targets, for major diseases such as cancer, neurological disorders, obesity and inflammation. Here, we review and discuss the structural biology of BET family BDs and their applications in major diseases.

  16. Estimation of differential code biases for Beidou navigation system using multi-GNSS observations: How stable are the differential satellite and receiver code biases?

    Science.gov (United States)

    Xue, Junchen; Song, Shuli; Zhu, Wenyao

    2016-04-01

    Differential code biases (DCBs) are important parameters that must be estimated accurately and reliably for high-precision GNSS applications. For optimal operational service performance of the Beidou navigation system (BDS), continuous monitoring and constant quality assessment of the BDS satellite DCBs are crucial. In this study, a global ionospheric model was constructed based on a dual system BDS/GPS combination. Daily BDS DCBs were estimated together with the total electron content from 23 months' multi-GNSS observations. The stability of the resulting BDS DCB estimates was analyzed in detail. It was found that over a long period, the standard deviations (STDs) for all satellite B1-B2 DCBs were within 0.3 ns (average: 0.19 ns) and for all satellite B1-B3 DCBs, the STDs were within 0.36 ns (average: 0.22 ns). For BDS receivers, the STDs were greater than for the satellites, with most values <2 ns. The DCBs of different receiver families are different. Comparison of the statistics of the short-term stability of satellite DCBs over different time intervals revealed that the difference in STD between 28- and 7-day intervals was small, with a maximum not exceeding 0.06 ns. In almost all cases, the difference in BDS satellite DCBs between two consecutive days was <0.8 ns. The main conclusion is that because of the stability of the BDS DCBs, they only require occasional estimation or calibration. Furthermore, the 30-day averaged satellite DCBs can be used reliably for the most demanding BDS applications.

  17. Assessment of precipitable water vapor derived from ground-based BeiDou observations with Precise Point Positioning approach

    Science.gov (United States)

    Li, Min; Li, Wenwen; Shi, Chuang; Zhao, Qile; Su, Xing; Qu, Lizhong; Liu, Zhizhao

    2015-01-01

    Precipitable water vapor (PWV) estimation from Global Positioning System (GPS) has been extensively studied and used for meteorological applications. However PWV estimation using the emerging BeiDou Navigation Satellite System (BDS) is very limited. In this paper the PWV estimation strategy and the evaluation of the results inferred from ground-based BDS observations using Precise Point Positioning (PPP) method are presented. BDS and GPS data from 10 stations distributed in the Asia-Pacific and West Indian Ocean regions during the year 2013 are processed using the PANDA (Position and Navigation Data Analyst) software package. The BDS-PWV and GPS-PWV are derived from the BDS-only and GPS-only observations, respectively. The PPP positioning differences between BDS-only and GPS-only show a standard deviation (STD) GPS-PWV at the HKTU station (Hong Kong, China) is compared with PWV derived from a radiosonde station (about 1 km distance) over a 6-month period. The GPS-PWV shows a good agreement with radiosonde-PWV with a bias of 0.002 mm and a STD of 2.49 mm while BDS-PWV has with a bias of -2.04 mm and STD 2.68 mm with respect to radiosonde-PWV. This indicates that the PWV estimated from the BDS can achieve similar precision as PWV from GPS. The BDS-PWV is compared to GPS-PWV at 10 stations. The mean bias and STD of their differences at 10 stations are 0.78 mm and 1.77 mm, respectively. The mean root mean square (RMS) value is 2.00 mm by considering the GPS-PWV as reference truth. This again confirms that the BDS-PWV has a good agreement with the GPS-PWV. It clearly indicates that the BDS is ready for the high precision meteorological applications in the Asia-Pacific and West Indian Ocean regions and that BDS alone can be used for PWV estimation with an accuracy comparable to GPS.

  18. Bodily Distress Syndrome

    DEFF Research Database (Denmark)

    Budtz-Lilly, Anna; Vestergaard, Mogens; Moth, Grete;

    2011-01-01

    : We will present data on the prevalence of BDS in a primary care population as well as the characteristics of patients with BDS. Characterization will include age, gender, severity of BDS, self evaluated health, health anxiety and mental health. Conclusion: Results from this study will make precise...... and clinically relevant contributions to the development of diagnostic classification for primary care patients who are poorly described in the present classification systems. Results from this study will help GPs diagnose patients with functional disorders and thereby provide the opportunity for...

  19. Impact of salt stress on the features and activities of root system for three desert halophyte species in their seedling stage

    Institute of Scientific and Technical Information of China (English)

    YI LiangPeng; MA Jian; LI Yan

    2007-01-01

    Linkage between belowground and aboveground sections of ecological system is mainly depending on root system. But root system is the parts of plant that people less understand. The absorption function of root system is closely related to their morphology and activity. Moreover root system can interact with the environmental stress under the adverse situation, and adjust its system to take adaptation responses in morphology and physiology to strengthen its survival chance. This research is focused on three desert halophyte species of H. ammodendron (C.A.Mey.) Bge., S. physophora Pall., and S.nitraria Pall. under solution culture, to study the differences of their root system morphology and activity in the seedling stage under varying salt concentration conditions. The study results show that: A certain salt concentration can promote development of these three halophytes; but rather high salt concentration will restrain their growth, in particular inhibit the root system development. Under the same salt concentration condition, S. nitraria Pall. grows fast and accumulates the largest amount of biomass. Under relatively low salt concentration, the length of axial root and the total length of root system of these three halophyte species are all increased; and compared to the checking samples, S.physophora Pall. occupies the top place of root system growth, but the high salt concentration will restrain the increase of total root length; among them, the impact intensity on S. physophora Pall. is lighter than to H. ammodendron (C.A.Mey.) Bge. and S. nitraria Pall. is lighter; the salinity does not bring distinct influence on the average diameter of root system of these three plant species, but trends to reducing the size; under the solution culture conditions, the middle and lower parts of the axial root of H. ammodendron (C.A.Mey.) Bge. and S. physophora Pall. are rather equally distributed, but the central zone of S. nitraria Pall. root system is more significantly

  20. 5th China Satellite Navigation Conference

    CERN Document Server

    Jiao, Wenhai; Wu, Haitao; Lu, Mingquan

    2014-01-01

    China Satellite Navigation Conference (CSNC) 2014 Proceedings presents selected research papers from CSNC2014, held on 21-23 May in Nanjing, China. The theme of CSNC2014 is 'BDS Application: Innovation, Integration and Sharing'. These papers discuss the technologies and applications of the Global Navigation Satellite System (GNSS), and the latest progress made in the China BeiDou System (BDS) especially. They are divided into 9 topics to match the corresponding sessions in CSNC2014, which broadly covered key topics in GNSS. Readers can learn about the BDS and keep abreast of the latest advances in GNSS techniques and applications.  SUN Jiadong is the Chief Designer of the Compass/ BDS, and the Academician of Chinese Academy of Sciences (CAS); JIAO Wenhai is a researcher at China Satellite Navigation Office; WU Haitao is a professor at Navigation Headquarters, CAS; LU Mingquan is a professor at Department of Electronic Engineering of Tsinghua University.

  1. Substitution patterns are GC-biased in divergent sequences across the metazoans.

    Science.gov (United States)

    Capra, John A; Pollard, Katherine S

    2011-01-01

    The fastest-evolving regions in the human and chimpanzee genomes show a remarkable excess of weak (A,T) to strong (G,C) nucleotide substitutions since divergence from their common ancestor. We investigated the phylogenetic extent and possible causes of this weak to strong (W → S) bias in divergent sequences (BDS) using recently sequenced genomes and recombination maps from eight trios of eukaryotic species. To quantify evidence for BDS, we inferred substitution histories using an efficient maximum likelihood approach with a context-dependent evolutionary model. We then annotated all lineage-specific substitutions in terms of W → S bias and density on the chromosomes. Finally, we used the inferred substitutions to calculate a BDS score-a log odds ratio between substitution type and density-and assessed its statistical significance with Fisher's exact test. Applying this approach, we found significant BDS in the coding and noncoding sequence of human, mouse, dog, stickleback, fruit fly, and worm. We also observed a significant lack of W → S BDS in chicken and yeast. The BDS score varies between species and across the chromosomes within each species. It is most strongly correlated with different genomic features in different species, but a strong correlation with recombination rates is found in several species. Our results demonstrate that a W → S substitution bias in fast-evolving sequences is a widespread phenomenon. The patterns of BDS observed suggest that a recombination-associated process, such as GC-biased gene conversion, is involved in the production of the bias in many species, but the strength of the BDS likely depends on many factors, including genome stability, variability in recombination rate over time and across the genome, the frequency of meiosis, and the amount of outcrossing in each species. PMID:21670083

  2. Substitution Patterns Are GC-Biased in Divergent Sequences across the Metazoans

    OpenAIRE

    Capra, John A.; Katherine S Pollard

    2011-01-01

    The fastest-evolving regions in the human and chimpanzee genomes show a remarkable excess of weak (A,T) to strong (G,C) nucleotide substitutions since divergence from their common ancestor. We investigated the phylogenetic extent and possible causes of this weak to strong (W→S) bias in divergent sequences (BDS) using recently sequenced genomes and recombination maps from eight trios of eukaryotic species. To quantify evidence for BDS, we inferred substitution histories using an efficient maxi...

  3. Evaluation of Intervention on Voluntary Blood Donation among 1st Prof Medical and Dental Students of Index Medical College, Indore (MP), India

    OpenAIRE

    Abhishek Bachhotiya, V K Arora, Piyusha Mahashabde

    2014-01-01

    Objective: Objectives of this study was to assess KAP regarding voluntary blood donation among 1stprof MBBS & BDS students of Index Medical College, Indore and also to evaluate the intervention in making the students aware about voluntary blood donation Methods: Among 209 students (125 MBBS, 84 BDS) a questionnaire was administered followed by participants’ visit to the hospital blood donation centre where a short interactive awareness session was organized. The willingness to donate b...

  4. An investigation of dielectric barrier discharge in Ar and Ar/NH3 mixture using cross-correlation spectroscopy

    OpenAIRE

    Kloc, P; Wagner, H-E; Trunec, D; Navrátil, Z; Fedoseev, G

    2010-01-01

    Abstract Dielectric barrier discharges (BDs) are known to operate in two distinctive modes. Filamentary mode of DB is characterized by large number of short lasting spatially bounded microdischarges. This type of discharge is typical for most cases of BDs at atmospheric pressure. Under some specific conditions another form of BD may arise. In this mode plasma covers uniformly the whole electrode area. This mode is usually referred to as diffuse or homogeneous mode of BD. This work presents...

  5. The World Modeler : the nexus between Janus and Battlefield Distributed Simulation-Developmental

    OpenAIRE

    Johnson, Matthew A.

    1994-01-01

    The United States Army has two disparate combat models; Janus and Battlefield Distributed Simulation-Developmental (BDS-D). Both facilitate training, tactical development and weapons analysis. The major problem addressed by this research is that entities existing in the Janus Combat Modeler cannot interact with entities in BDS-D. If interaction is made possible, it would produce a synergy between the combined models, each model bringing advantages to the other. The approach taken was first to...

  6. DETECTION OF BROWN DWARF LIKE OBJECTS IN THE CORE OF NGC 3603

    International Nuclear Information System (INIS)

    We used near-infrared data obtained with the Wide Field Camera 3 on the Hubble Space Telescope to identify objects having the colors of brown dwarfs (BDs) in the field of the massive galactic cluster NGC 3603. These are identified through a combination of narrow- and medium-band filters which span the J and H bands and are particularly sensitive to the presence of the 1.3-1.5 μm H2O molecular band unique to BDs. We provide a calibration of the relationship between effective temperature and color for both field stars and BDs. This photometric method provides effective temperatures for BDs to an accuracy of ±350 K relative to spectroscopic techniques. This accuracy is shown to be not significantly affected by either stellar surface gravity or uncertainties in the interstellar extinction. We identify nine objects having effective temperatures between 1700 and 2200 K, typical of BDs, observed J-band magnitudes in the range 19.5-21.5, and that are strongly clustered toward the luminous core of NGC 3603. However, if these are located at the distance of the cluster, they are far too luminous to be normal BDs. We argue that it is unlikely that these objects are either artifacts of our data set, normal field BDs/M-type giants, or extragalactic contaminants and, therefore, might represent a new class of stars having the effective temperatures of BDs but with luminosities of more massive stars. We explore the interesting scenario in which these objects would be normal stars that have recently tidally ingested a hot Jupiter, the remnants of which are providing a short-lived extended photosphere to the central star. In this case, we would expect them to show the signature of fast rotation.

  7. Factor structure and construct validity of the Behavioral Dyscontrol Scale-II.

    Science.gov (United States)

    Shura, Robert D; Rowland, Jared A; Yoash-Gantz, Ruth E

    2015-01-01

    The Behavioral Dyscontrol Scale-II (BDS-II) was developed as an improved scoring method to the original BDS, which was designed to evaluate the capacity for independent regulation of behavior and attention. The purpose of this study was to evaluate the factor structure and construct validity of the BDS-II, which had not been adequately re-examined since the development of the new scoring system. In a sample of 164 Veterans with a mean age of 35 years, exploratory factor analysis was used to evaluate BDS-II latent factor structure. Correlations and regressions were used to explore validity against 22 psychometrically sound neurocognitive measures across seven neurocognitive domains of sensation, motor output, processing speed, attention, visual-spatial reasoning, memory, and executive functions. Factor analysis found a two-factor solution for this sample which explained 41% of the variance in the model. Validity analyses found significant correlations among the BDS-II scores and all other cognitive domains except sensation and language (which was not evaluated). Hierarchical regressions revealed that PASAT performance was strongly associated with all three BDS-II scores; dominant hand Finger Tapping Test was also associated with the Total score and Factor 1, and CPT-II Commissions was also associated with Factor 2. These results suggest the BDS-II is both a general test of cerebral functioning, and a more specific test of working memory, motor output, and impulsivity. The BDS-II may therefore show utility with younger populations for measuring frontal lobe abilities and might be very sensitive to neurological injury. PMID:25650736

  8. Management of bipolar disorders in women by nonpharmacological methods

    OpenAIRE

    Naik, Sujit Kumar

    2015-01-01

    Several reasons justify the need for nonpharmacological interventions for bipolar disorder (BD) in women. This review focuses on psychosocial therapies for BDs in women. The research evidence for a wide range of psychosocial interventions for the management of BDs in women has been presented. All the interventions have some common components like targeting disease management, information regarding illness, and coping skills. There also are distinctive features like cognitive restructuring and...

  9. Research and Realization of Deformation Monitoring Algorithm with Millimeter Level Precision Based on BeiDou Navigation Satellite System

    Directory of Open Access Journals (Sweden)

    XIAO Yugang

    2016-01-01

    Full Text Available The deformation monitoring algorithm with millimeter level precision based on BeiDou Navigation Satellite System (BDS was researched. The TurboEdit method was improved to detect small cycle slips, e.g. 1 cycle. Focusing on BDS constellation, a more efficient algorithm used to construct double-differenced observations was developed. The Bootstrap+Decision function method was utilized to improve the probability of biases fixing. Based on the improved algorithm above, a deformation monitoring software based on BDS was achieved. Afterwards, the availability of BDS in the field of deformation monitoring was analyzed in terms of satellites distribution and precision and accuracy of solutions, utilizing the observations acquired from the experimental platform. The conclusion was drawn that currently BDS is similar to GPS in terms of satellites distribution in the test area. The precision of short baselines derived from BDS is better than 1 mm for the horizontal components, better than 2 mm for the vertical components, which is still a little lower than GPS.

  10. Blowing-machine representation of various meteorological situations for the study of rejection into the atmosphere

    International Nuclear Information System (INIS)

    A stratified blowing-machine has been built making it possible to introduce into the tests a vertical temperature gradient. The similitude conditions have been examined. The development tests have made it possible to observe and to film the shape of the smoke pall emitted by a chimney in different cases. Stationary waves have been obtained in steady state conditions and the cross-section of the pall has also been studied. It appears that certain diffusion studies justify the use of a stratified blowing-machine. (author)

  11. Modelling of the Earth's transmission spectrum in the framework of one-slab model

    OpenAIRE

    Pavlenko Ya V.; Polinovskyi G.; Martin E.L.

    2013-01-01

    We discuss the possibility of using the transmission spectrum of the Earth in the measurements of the molecules abundance ratios. We use optical and near infrared transmission spectrum of the Earth obtained during observations of a lunar eclipse in 2008 by Enric Palle and others (E. Pallé et al., 2009). This task is interesting in terms of estimation of the chemical composition of the Earth-like planets around other stars during their transits. We use one-slab model approach for modelling tra...

  12. The disease-modifying effects of a Sativex-like combination of phytocannabinoids in mice with experimental autoimmune encephalomyelitis are preferentially due to Δ9-tetrahydrocannabinol acting through CB1 receptors.

    Science.gov (United States)

    Moreno-Martet, Miguel; Feliú, Ana; Espejo-Porras, Francisco; Mecha, Miriam; Carrillo-Salinas, Francisco J; Fernández-Ruiz, Javier; Guaza, Carmen; de Lago, Eva

    2015-11-01

    Sativex(®), an equimolecular combination of Δ(9)-tetrahydrocannabinol-botanical drug substance (Δ(9)-THC-BDS) and cannabidiol-botanical drug substance (CBD-BDS), is a licensed medicine that may be prescribed for alleviating specific symptoms of multiple sclerosis (MS) such as spasticity and pain. However, further evidence suggest that it could be also active as disease-modifying therapy given the immunomodulatory, anti-inflammatory and cytoprotective properties of their two major components. In this study, we investigated this potential in the experimental autoimmune encephalitis (EAE) model of MS in mice. We compared the effect of a Sativex-like combination of Δ(9)-THC-BDS (10 mg/kg) and CBD-BDS (10 mg/kg) with Δ(9)-THC-BDS (20 mg/kg) or CBD-BDS (20 mg/kg) administered separately by intraperitoneal administration to EAE mice. Treatments were initiated at the time that symptoms appear and continued up to the first relapse of the disease. The results show that the treatment with a Sativex-like combination significantly improved the neurological deficits typical of EAE mice, in parallel with a reduction in the number and extent of cell aggregates present in the spinal cord which derived from cell infiltration to the CNS. These effects were completely reproduced by the treatment with Δ(9)-THC-BDS alone, but not by CBD-BDS alone which only delayed the onset of the disease without improving disease progression and reducing the cell infiltrates in the spinal cord. Next, we investigated the potential targets involved in the effects of Δ(9)-THC-BDS by selectively blocking CB(1) or PPAR-γ receptors, and we found a complete reversion of neurological benefits and the reduction in cell aggregates only with rimonabant, a selective CB(1) receptor antagonist. Collectively, our data support the therapeutic potential of Sativex as a phytocannabinoid formulation capable of attenuating EAE progression, and that the active compound was Δ(9)-THC-BDS acting through CB(1

  13. Approaching zero: temporal effects of a restrictive antibiotic policy on hospital-acquired Clostridium difficile, extended-spectrum β-lactamase-producing coliforms and meticillin-resistant Staphylococcus aureus.

    Science.gov (United States)

    Dancer, S J; Kirkpatrick, P; Corcoran, D S; Christison, F; Farmer, D; Robertson, C

    2013-02-01

    A restrictive antibiotic policy banning routine use of ceftriaxone and ciprofloxacin was implemented in a 450-bed district general hospital following an educational campaign. Monthly consumption of nine antibiotics was monitored in defined daily doses (DDDs) per 1000 patient-occupied bed-days (1000 pt-bds) 9 months before until 16 months after policy introduction. Hospital-acquired Clostridium difficile, meticillin-resistant Staphylococcus aureus (MRSA) and extended-spectrum β-lactamase (ESBL)-producing coliform cases per month/1000 pt-bds were identified and reviewed throughout the hospital. Between the first and final 6 months of the study, average monthly consumption of ceftriaxone reduced by 95% (from 46.213 to 2.129 DDDs/1000 pt-bds) and that for ciprofloxacin by 72.5% (109.804 to 30.205 DDDs/1000 pt-bds). Over the same periods, hospital-acquisition rates for C. difficile reduced by 77% (2.398 to 0.549 cases/1000 pt-bds), for MRSA by 25% (1.187 to 0.894 cases/1000 pt-bds) and for ESBL-producing coliforms by 17% (1.480 to 1.224 cases/1000 pt-bds). Time-lag modelling confirmed significant associations between ceftriaxone and C. difficile cases at 1 month (correlation 0.83; P<0.005), and between ciprofloxacin and ESBL-producing coliform cases at 2 months (correlation 0.649; P=0.002). An audit performed 3 years after the policy showed sustained reduction in C. difficile rates (0.259 cases/1000 pt-bds), with additional decreases for MRSA (0.409 cases/1000 pt-bds) and ESBL-producing coliforms (0.809 cases/1000 pt-bds). In conclusion, banning two antibiotics resulted in an immediate and profound reduction in hospital-acquired C. difficile, with possible longer-term effects on MRSA and ESBL-producing coliform rates. Antibiotic stewardship is fundamental in the control of major hospital pathogens. PMID:23276500

  14. Microbial phytase addition resulted in a greater increase in phosphorus digestibility in dry-fed compared with liquid-fed non-heat-treated wheat-barley-maize diets for pigs.

    Science.gov (United States)

    Blaabjerg, K; Thomassen, A-M; Poulsen, H D

    2015-02-01

    The objective was to evaluate the effect of microbial phytase (1250 FTU/kg diet with 88% dry matter (DM)) on apparent total tract digestibility (ATTD) of phosphorus (P) in pigs fed a dry or soaked diet. Twenty-four pigs (65±3 kg) from six litters were used. Pigs were housed in metabolism crates and fed one of four diets for 12 days; 5 days for adaptation and 7 days for total, but separate collection of feces and urine. The basal diet was composed of wheat, barley, maize, soybean meal and no mineral phosphate. Dietary treatments were: basal dry-fed diet (BDD), BDD with microbial phytase (BDD+phy), BDD soaked for 24 h at 20°C before feeding (BDS) and BDS with microbial phytase (BDS+phy). Supplementation of microbial phytase increased ATTD of DM and crude protein (N×6.25) by 2 and 3 percentage units (Pwheat and barley phytases during soaking. On the other hand, soaking of BDS+phy did not increase ATTD of P significantly compared with BDD+phy despite that 76% of the phytate in BDS+phy was degraded before feeding. In conclusion, soaking of BDS containing solely plant phytase provided a great potential for increasing ATTD of P. However, this potential was not present when microbial phytase (1250 FTU/kg diet) was supplemented, most likely because soaking of BDS+phy for 24 h at 20°C did not result in a complete degradation of phytate before feeding. PMID:25245085

  15. Eestlaste pension kinnisvaraturu meelevallas / Anne Oja

    Index Scriptorium Estoniae

    Oja, Anne, 1970-

    2007-01-01

    Ilmunud ka: Delovõje Vedomosti 22. aug. lk. 6. Eesti pensionifondid on kinnisvarasse paigutanud umbes miljard krooni. Kinnisvarafirmade võlakirjade hind võib kujuneda madalaks. Pankade kommentaarid. Vt. samas: Tulevased pensionärid magavad rahulikult. Tabel: Pensionifondide investeeringud kinnisvarasse. Kommenteerivad: Ingmar Mattus, Kalle Palling, Karoli Hindriks, Pertti Rahnel, Andre Nõmm, Urmas Laur, Kristjan Lepik. Kommentaarid ainult eestikeelse art. juures

  16. Väikeste ridamajade rida Kloostrimetsas = A Row of Little Row Houses in Kloostrimetsa / Urmas Oja

    Index Scriptorium Estoniae

    Oja, Urmas, 1981-2012

    2003-01-01

    Neljast ridaelamust, millest kaks on propjekteerinud Ado Eigi (Ado Eigi Arhitektuuribüroo, konstruktsioonid: Uno Pall, projekt 2002, valminud 2003), ühe Ott Kadarik ja Mihkel Tüür (COO Arhitektid, projekt 2002, valminud 2003) ning ühe arhitektuuribüroo Kosmos (valminud 2004). Sisevaade, 6 välisvaadet, 5 korruste plaani

  17. Eesti Energia nõukogu liikmed Jaotusvõrgu hinnatõusutaotlust kommenteerima ei kipu / Katre Pilvinski

    Index Scriptorium Estoniae

    Pilvinski, Katre

    2010-01-01

    Eesti Energia nõukogu liige Kalle Palling kommenteerib peaminister Andrus Ansipi öeldut, et Eesti Energia investeeringud tuleb üle vaadata. Nõukogu liikme Rein Kilgi sõnul tunduvad talle rünnakud Eesti Energia vastu ülekohtused

  18. Mõtlejate mõjud ja sotsiaalne aktsionism Tallinna galeriides / Margaret Tali

    Index Scriptorium Estoniae

    Tali, Margaret

    2002-01-01

    Marko Laimre näitus "Must pall" Tallinna Kunstihoones, Liina Siibi näitus "Klips" (plakatid, videod) Hansapanga galeriis, Stuudio 22 näitus "déja vu" (graafika) Pärnu mnt. 27 galeriis, Eesti Kunstiakadeemia üliõpilaste joonistused "Tühjus ja Ruum" G-galeriis

  19. TWAS Participating in Social Advancement --An Interview with Prof. Jacob Palis

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    "We should have the promotion of research and development in the industry, and for that scientists should be hired ... Science not only should be promoted by its intellectual challenges of understanding nature, but also should be towards applications in benefit of Society, without reservations that science would be less noble because of that." Prof. Jacob Palls.

  20. Morphological and molecular characterization of Globodera populations from Oregon and Idaho

    Science.gov (United States)

    A new species of Globodera, identified from three potato fields, is described herein as Globodera pseudopallida n. sp. Morphologically, G. pseudopallida n. sp. exhibits some unique features that are not consistent between populations; but molecularly, G. pseudopallida n. sp. is distinct from G. pall...

  1. Kontseptuaalne ja liikumispõhine nüüdistants Täiskuu tantsufestivalil Soomes / Evelin Lagle

    Index Scriptorium Estoniae

    Lagle, Evelin, 1986-

    2010-01-01

    Tantsufestivalist "Täudenkuun Tanssit" (Full Moon Dance Festival). Tantsulavastustest - Tommi Kitti "Riff", Jyrki Karttuneni "Situation Room", Kenneth Kvanströmi "Destruction Song", Liisa Petti "Mabel or the Gueen of Bones", Elina Pirineni "A Friend of the Pianist", Johanna Tuukkaneni "Outstanding Performance" ja Palle Granhoj sooloetendus "(...It's a Very Big Secret...)"

  2. Education, Learning and Development in the Periphery

    DEFF Research Database (Denmark)

    Rasmussen, Palle

    2012-01-01

    Palle Rasmussens artikkel handler om utdannelse, læring og utvikling i utkantområder, belyst gjennom utdanningens rolle i den regionale utviklingen i Danmark. Rasmussen peker på at Danmark har et velutviklet utdanningssystem som sikrer en relativt lik fordeling av befolkningens utdanningsmulighet...

  3. Study on Clematisnzans Hurica Rupr's Identification and Statographic Fingerprint Atlas%东北铁线莲的鉴别与色谱指纹图谱的研究

    Institute of Scientific and Technical Information of China (English)

    曹婷婷; 杨帆; 邢晶晶

    2011-01-01

    @@ 毛茛科铁线莲属植物约有300种.我国有108种.其中作为正品威灵仙人药的为威灵仙 Clematis chinesis Osbeck,棉团铁线莲 Clematishexapetala Pall 和东北铁线莲 Clematisnzans hurica Rupr的干燥根及根茎.

  4. Obama and Cameron’s Ping-pong Diplomacy Show

    Institute of Scientific and Technical Information of China (English)

    李新

    2011-01-01

    They seemed like best mates. Every time one of them got a point,they did a high fiv(e击掌相庆). The men were the British Prime Minister,David Cameron, and the President of the USA, Barack Obama.The palling around(结伴玩耍)took place during Mr. Obama’s state

  5. Hydrodynamic behaviour of a gas—solid counter-current packed column at trickle flow

    NARCIS (Netherlands)

    Roes, A.W.M.; Swaaij, van W.P.M.

    1979-01-01

    Trickle flow of a more or less fluidized catalyst through a packed column is a promising new gas—solid counter-current operation. The hydrodynamic, behaviour of such a column, filled with dumped PALL rings, has been investigated, while some results have been obtained with RASCHIG rings and cylindric

  6. "Vaesus on disainerile parim aeg" / Masayo Ave

    Index Scriptorium Estoniae

    Ave, Masayo

    2007-01-01

    Masayo Ave oma elust Euroopas, probleemidest ja kohalike väärtuste arendamisest disainis ja sellest, et puudus paneb aju tööle. Illustratsioonidel valik tema toodetest - öövalgusti Fish Eye, täispuhutav pall-iste, laua- ja seinalamp Genesi, päevapadi Toft jt.

  7. ВЛИЯНИЕ НАНОПОРОШКОВ ОКСИДОВ МЕТАЛЛОВ НА УСПЕХ ПРОХОЖДЕНИЯ ЛИЧИНОЧНЫХ СТАДИЙ РАЗВИТИЯ ОЗЕРНОЙ ЛЯГУШКОЙ (RANA RIDIBUNDA PALL.)

    OpenAIRE

    Шиян, Анна

    2011-01-01

    В статье рассмотрено влияние четырех оксидов нанометаллов на головастиков озерной лягушки в чистой воде и в сточных водах сахарного завода низких концентраций. Выявлено протекторное действие трех нанометаллов, характеризующееся увеличением темпов роста и снижением смертности у головастиков в сточной воде сахарных заводов...

  8. Detection of brown dwarf-like objects in the core of NGC3603

    CERN Document Server

    Spezzi, Loredana; De Marchi, Guido; Young, Erick T; Paresce, Francesco; Dopita, Michael A; Andersen, Morten; Panagia, Nino; Balick, Bruce; Bond, Howard E; Calzetti, Daniela; Carollo, C Marcella; Disney, Michael J; Frogel, Jay A; Hall, Donald N B; Holtzman, Jon A; Kimble, Randy A; McCarthy, Patrick J; O'Connell, Robert W; Saha, Abhijit; Silk, Joseph I; Trauger, John T; Walker, Alistair R; Whitmore, Bradley C; Windhorst, Rogier A

    2011-01-01

    We use near-infrared data obtained with the Wide Field Camera 3 (WFC3) on the Hubble Space Telescope to identify objects having the colors of brown dwarfs (BDs) in the field of the massive galactic cluster NGC 3603. These are identified through use of a combination of narrow and medium band filters spanning the J and H bands, and which are particularly sensitive to the presence of the 1.3-1.5{\\mu}m H2O molecular band - unique to BDs. We provide a calibration of the relationship between effective temperature and color for both field stars and for BDs. This photometric method provides effective temperatures for BDs to an accuracy of {\\pm}350K relative to spectroscopic techniques. This accuracy is shown to be not significantly affected by either stellar surface gravity or uncertainties in the interstellar extinction. We identify nine objects having effective temperature between 1700 and 2200 K, typical of BDs, observed J-band magnitudes in the range 19.5-21.5, and that are strongly clustered towards the luminous...

  9. A CURRICULAR PARADIGM BASED UPON VEDIC EPISTEMOLOGY: AN APPROACH TO DEVELOPING THE WHOLE PERSON

    Directory of Open Access Journals (Sweden)

    Dr. Kumar LAXMAN

    2012-10-01

    Full Text Available The Bhaktivedanta Dharma School (BDS provides quality but yet affordable holistic education to the local Indonesian community in Bali. The school’s educational orientation is inspired by the Vedic (Hindu goals of fruition of knowledge (Vedanta or the essence of the Vedic scriptures and devotion (Bhakti to God (Krishna. The curriculum integrates the best of both the eastern and western approaches to enriching young minds. The strengths of both value systems are seen to be crucial in the all-round, dynamic development of children. Not only is academic excellence emphasized but character development and awareness of the higher spiritual purpose of life are also imparted to the kids. The role of the teacher extends beyond the taught curriculum and s/he plays a vital role in the character development of the child, through his or her own personal example. This paper examines the pedagogical effectiveness of the implemented framework of holistic education at BDS based upon the perceptions and experiences of the teachers working in the school. An ethnographic approach was employed as the main research methodology with participant observation and open-ended interviewing the primary means of data collection and analysis. A total of six teachers working at BDS were interviewed in this study. The findings of the study provide deeper insights on the differences between BDS and mainstream, traditional schools in terms of their structural and curricular characteristics and the key challenges participant teachers faced in orientating to the alternative learning culture of BDS.

  10. Impact of tracking station distribution structure on BeiDou satellite orbit determination

    Science.gov (United States)

    Zhang, Rui; Zhang, Qin; Huang, Guanwen; Wang, Le; Qu, Wei

    2015-11-01

    The racking station distribution structure plays an important role in GNSS satellite orbit determination. Due to the current satellite distribution of the BeiDou satellite navigation system (BDS), the problem how to construct a reasonable distribution of tracking stations to obtain BDS satellite orbits with high precision has become a highly imperative issue. Based on the theory of dynamic orbit determination, two different station distributions were analyzed to study their impact on BDS precise and real-time orbit determination. Subsequently, the impact of Satellite Position Dilution of Precision (SPDOP) values on orbit determination was analyzed. Finally, an improved scheme for the tracking station distribution was designed based on the original scheme. The numerical results show that the SPDOP value can be used to evaluate the contribution of the tracking stations distribution on the BDS IGSO and MEO satellites orbit determination. In addition, the tracking stations which focus on the Asia-Pacific region play a key role in current BDS orbit determination.

  11. BANYAN. VII. A New Population of Young Substellar Candidate Members of Nearby Moving Groups from the BASS Survey

    CERN Document Server

    Gagné, Jonathan; Cruz, Kelle L; Lafrenière, David; Doyon, René; Malo, Lison; Burgasser, Adam J; Naud, Marie-Eve; Artigau, Étienne; Bouchard, Sandie; Gizis, John E; Albert, Loïc

    2015-01-01

    [Abbreviated] We present the results of a near-infrared (NIR) spectroscopic follow-up survey of 182 M4-L7 low-mass stars and brown dwarfs (BDs) from the BANYAN All-Sky Survey (BASS) for candidate members of nearby, young moving groups (YMGs). We confirm signs of low-gravity for 42 new BD discoveries with estimated masses between 8-75 $M_{Jup}$ and identify previously unrecognized signs of low gravity for 24 known BDs. This allows us to refine the fraction of low-gravity dwarfs in the high-probability BASS sample to $\\sim$82%. We use this unique sample of 66 young BDs, supplemented with 22 young BDs from the literature, to construct new empirical NIR absolute magnitude and color sequences for low-gravity BDs. We obtain a spectroscopic confirmation of low-gravity for 2MASS J14252798-3650229, which is a new $\\sim$27 $M_{Jup}$, L4 $\\gamma$ bona fide member of AB Doradus. We identify a total of 19 new low-gravity candidate members of YMGs with estimated masses below 13 $M_{Jup}$, seven of which have kinematically ...

  12. HABITABLE PLANETS ECLIPSING BROWN DWARFS: STRATEGIES FOR DETECTION AND CHARACTERIZATION

    Energy Technology Data Exchange (ETDEWEB)

    Belu, Adrian R.; Selsis, Franck; Raymond, Sean N.; Bolmont, Emeline [Universite de Bordeaux, LAB, UMR 5804, F-33270, Floirac (France); Palle, Enric [Instituto de Astrofisica de Canarias, E-38205 La Laguna (Spain); Street, Rachel [Las Cumbres Observatory Global Telescope Network, 6740 Cortona Drive, Suite 102, Goleta, CA 93117 (United States); Sahu, D. K.; Anupama, G. C. [Indian Institute of Astrophysics, Koramangala, Bangalore 560034 (India); Von Braun, Kaspar [NASA Exoplanet Science Institute, California Institute of Technology, MC 100-22, Pasadena, CA 91125 (United States); Figueira, Pedro [Centro de Astrofisica, Universidade do Porto, Rua das Estrelas, 4150-762 Porto (Portugal); Ribas, Ignasi, E-mail: belu@obs.u-bordeaux1.fr [Institut de Ciencies de l' Espai (CSIC-IEEC), Campus UAB, Facultat de Ciencies, Torre C5, parell, 2a pl., E-08193 Bellaterra (Spain)

    2013-05-10

    Given the very close proximity of their habitable zones, brown dwarfs (BDs) represent high-value targets in the search for nearby transiting habitable planets that may be suitable for follow-up occultation spectroscopy. In this paper, we develop search strategies to find habitable planets transiting BDs depending on their maximum habitable orbital period (P{sub HZ{sub out}}). Habitable planets with P{sub HZ{sub out}} shorter than the useful duration of a night (e.g., 8-10 hr) can be screened with 100% completeness from a single location and in a single night (near-IR). More luminous BDs require continuous monitoring for longer duration, e.g., from space or from a longitude-distributed network (one test scheduling achieved three telescopes, 13.5 contiguous hours). Using a simulated survey of the 21 closest known BDs (within 7 pc) we find that the probability of detecting at least one transiting habitable planet is between 4.5{sup +5.6}{sub -1.4}% and 56{sup +31}{sub -13}%, depending on our assumptions. We calculate that BDs within 5-10 pc are characterizable for potential biosignatures with a 6.5 m space telescope using {approx}1% of a five-year mission's lifetime spread over a contiguous segment only one-fifth to one-tenth of this duration.

  13. Analysis of BeiDou Satellite Measurements with Code Multipath and Geometry-Free Ionosphere-Free Combinations

    Directory of Open Access Journals (Sweden)

    Qile Zhao

    2016-01-01

    Full Text Available Using GNSS observable from some stations in the Asia-Pacific area, the carrier-to-noise ratio (CNR and multipath combinations of BeiDou Navigation Satellite System (BDS, as well as their variations with time and/or elevation were investigated and compared with those of GPS and Galileo. Provided the same elevation, the CNR of B1 observables is the lowest among the three BDS frequencies, while B3 is the highest. The code multipath combinations of BDS inclined geosynchronous orbit (IGSO and medium Earth orbit (MEO satellites are remarkably correlated with elevation, and the systematic “V” shape trends could be eliminated through between-station-differencing or modeling correction. Daily periodicity was found in the geometry-free ionosphere-free (GFIF combinations of both BDS geostationary Earth orbit (GEO and IGSO satellites. The variation range of carrier phase GFIF combinations of GEO satellites is −2.0 to 2.0 cm. The periodicity of carrier phase GFIF combination could be significantly mitigated through between-station differencing. Carrier phase GFIF combinations of BDS GEO and IGSO satellites might also contain delays related to satellites. Cross-correlation suggests that the GFIF combinations’ time series of some GEO satellites might vary according to their relative geometries with the sun.

  14. Dielectric response and novel electromagnetic modes in three-dimensional Dirac semimetal films

    Science.gov (United States)

    Kotov, O. V.; Lozovik, Yu. E.

    2016-06-01

    Using the Kubo formalism we have calculated the local dynamic conductivity of a bulk, i.e., three-dimensional (3D), Dirac semimetal (BDS). We obtain that at frequencies lower than Fermi energy the metallic response in a BDS film manifests in the existence of surface-plasmon polaritons, but at higher frequencies the dielectric response is dominated and it occurs that a BDS film behaves as a dielectric waveguide. At this dielectric regime we predict the existence inside a BDS film of novel electromagnetic modes, a 3D analog of the transverse electric waves in graphene. We also find that the dielectric response manifests as the wide-angle passband in the mid-infrared (IR) transmission spectrum of light incident on a BDS film, which can be used for the interferenceless omnidirectional mid-IR filtering. The tuning of the Fermi level of the system allows us to switch between the metallic and the dielectric regimes and to change the frequency range of the predicted modes. This makes BDSs promising materials for photonics and plasmonics.

  15. Analysis of BeiDou Satellite Measurements with Code Multipath and Geometry-Free Ionosphere-Free Combinations

    Science.gov (United States)

    Zhao, Qile; Wang, Guangxing; Liu, Zhizhao; Hu, Zhigang; Dai, Zhiqiang; Liu, Jingnan

    2016-01-01

    Using GNSS observable from some stations in the Asia-Pacific area, the carrier-to-noise ratio (CNR) and multipath combinations of BeiDou Navigation Satellite System (BDS), as well as their variations with time and/or elevation were investigated and compared with those of GPS and Galileo. Provided the same elevation, the CNR of B1 observables is the lowest among the three BDS frequencies, while B3 is the highest. The code multipath combinations of BDS inclined geosynchronous orbit (IGSO) and medium Earth orbit (MEO) satellites are remarkably correlated with elevation, and the systematic “V” shape trends could be eliminated through between-station-differencing or modeling correction. Daily periodicity was found in the geometry-free ionosphere-free (GFIF) combinations of both BDS geostationary Earth orbit (GEO) and IGSO satellites. The variation range of carrier phase GFIF combinations of GEO satellites is −2.0 to 2.0 cm. The periodicity of carrier phase GFIF combination could be significantly mitigated through between-station differencing. Carrier phase GFIF combinations of BDS GEO and IGSO satellites might also contain delays related to satellites. Cross-correlation suggests that the GFIF combinations’ time series of some GEO satellites might vary according to their relative geometries with the sun. PMID:26805831

  16. Analysis of BeiDou Satellite Measurements with Code Multipath and Geometry-Free Ionosphere-Free Combinations.

    Science.gov (United States)

    Zhao, Qile; Wang, Guangxing; Liu, Zhizhao; Hu, Zhigang; Dai, Zhiqiang; Liu, Jingnan

    2016-01-01

    Using GNSS observable from some stations in the Asia-Pacific area, the carrier-to-noise ratio (CNR) and multipath combinations of BeiDou Navigation Satellite System (BDS), as well as their variations with time and/or elevation were investigated and compared with those of GPS and Galileo. Provided the same elevation, the CNR of B1 observables is the lowest among the three BDS frequencies, while B3 is the highest. The code multipath combinations of BDS inclined geosynchronous orbit (IGSO) and medium Earth orbit (MEO) satellites are remarkably correlated with elevation, and the systematic "V" shape trends could be eliminated through between-station-differencing or modeling correction. Daily periodicity was found in the geometry-free ionosphere-free (GFIF) combinations of both BDS geostationary Earth orbit (GEO) and IGSO satellites. The variation range of carrier phase GFIF combinations of GEO satellites is -2.0 to 2.0 cm. The periodicity of carrier phase GFIF combination could be significantly mitigated through between-station differencing. Carrier phase GFIF combinations of BDS GEO and IGSO satellites might also contain delays related to satellites. Cross-correlation suggests that the GFIF combinations' time series of some GEO satellites might vary according to their relative geometries with the sun. PMID:26805831

  17. Dynamics at the Polymer/Nanoparticle Interface in Poly(2-vinylpyridine)/Silica Nanocomposites.

    Energy Technology Data Exchange (ETDEWEB)

    Holt, Adam P [ORNL; Griffin, Phillip [University of Tennessee (UTK) and Oak Ridge National Laboratory (ORNL); Bocharova, Vera [ORNL; Agapov, Alexander L [ORNL; Imel, Adam E [ORNL; Dadmun, Mark D [ORNL; Sangoro, Joshua R [ORNL; Sokolov, Alexei P [ORNL

    2014-01-01

    The static and dynamic properties of poly(2-vinylpyridine)/silica nanocomposites are investigated by temperature modulated differential scanning calorimetry, broadband dielectric spectroscopy (BDS), small-angle X-ray scattering (SAXS), and transmission electron microscopy. Both BDS and SAXS detect the existence of an interfacial polymer layer on the surface of nanoparticles. The results show that whereas the calorimetric glass transition temperature varies only weakly with nanoparticle loading, the segmental mobility of the polymer interfacial layer is slower than the bulk polymer by 2 orders of magnitude. Detailed analysis of BDS and SAXS data reveal that the interfacial layer has a thickness of 4 6 nm irrespective of the nanoparticle concentration. These results demonstrate that in contrast to some recent articles on polymer nanocomposites, the interfacial polymer layer is by no means a dead layer . However, its existence might provide some explanation for controversies surrounding the dynamics of polymer nanocomposites.

  18. Improved Measurement of Absolute Hadronic Branching Fractions of the Ds+ Meson

    CERN Document Server

    Onyisi, P U E; Cinabro, D; Smith, M J; Zhou, P; Naik, P; Rademacker, J; Edwards, K W; Briere, R A; Vogel, H; Rosner, J L; Alexander, J P; Cassel, D G; Das, S; Ehrlich, R; Gibbons, L; Gray, S W; Hartill, D L; Heltsley, B K; Kreinick, D L; Kuznetsov, V E; Patterson, J R; Peterson, D; Riley, D; Ryd, A; Sadoff, A J; Shi, X; Sun, W M; Yelton, J; Rubin, P; Lowrey, N; Mehrabyan, S; Selen, M; Wiss, J; Libby, J; Kornicer, M; Mitchell, R E; Besson, D; Pedlar, T K; Cronin-Hennessy, D; Hietala, J; Dobbs, S; Metreveli, Z; Seth, K K; Tomaradze, A; Xiao, T; Powell, A; Thomas, C; Wilkinson, G; Asner, D M; Tatishvili, G; Ge, J Y; Miller, D H; Shipsey, I P J; Xin, B; Adams, G S; Napolitano, J; Ecklund, K M; Insler, J; Muramatsu, H; Pearson, L J; Thorndike, E H; Artuso, M; Blusk, S; Mountain, R; Skwarnicki, T; Stone, S; Wang, J C; Zhang, L M

    2013-01-01

    The branching fractions of Ds meson decays serve to normalize many measurements of processes involving charm quarks. Using 586 pb^-1 of e+ e- collisions recorded at a center of mass energy of 4.17 GeV, we determine absolute branching fractions for 13 Ds decays in 16 reconstructed final states with a double tag technique. In particular we make a precise measurement of the branching fraction B(Ds -> K- K+ pi+) = (5.55 +- 0.14 +- 0.13)%, where the uncertainties are statistical and systematic respectively. We find a significantly reduced value of B(Ds -> pi+ pi0 eta') compared to the world average, and our results bring the inclusively and exclusively measured values of B(Ds -> eta' X)$ into agreement. We also search for CP-violating asymmetries in Ds decays and measure the cross-section of e+ e- -> Ds* Ds at Ecm = 4.17 GeV.

  19. A CONCEPTUAL TRAJECTORY MULTIDIMENSIONAL MODEL: AN APPLICATION TO PUBLIC TRANSPORTATION

    Directory of Open Access Journals (Sweden)

    FRANCISCO MORENO

    2011-01-01

    Full Text Available Actualmente, gracias a tecnologías como los sistemas de posicionamiento global y dispositivos móviles provistos de sensores, se puede recopilar una gran cantidad de datos sobre objetos móviles, e.g., datos relacionados con la trayectoria seguida por estos objetos. Por otra parte, las Bodegas de Datos (BDs, usualmente modeladas mediante una vista multidimensional de los datos, son bases de datos especializadas para ayudar en la toma de decisiones. Desafortunadamente, las BDs convencionales ofrecen poco soporte para la gestión de trayectorias. Aunque existen algunas propuestas que tratan con BDs de trayectorias, ninguna de ellas se enfoca en su modelamiento conceptual multidimensional. En este artículo se extiende un modelo conceptual multidimensional espacial donde se incorporan las trayectorias como conceptos de primera clase. Con el fi n de mostrar la conveniencia de la propuesta, se presenta un ejemplo relacionado con transporte público.

  20. Folic acid and primary prevention of birth defects.

    Science.gov (United States)

    Taruscio, Domenica; Carbone, Pietro; Granata, Orietta; Baldi, Francesca; Mantovani, Alberto

    2011-01-01

    Birth defects (BDs) are an important public health problem, due to their overall incidence, occurring in 2-3% of live births in European Union. Neural tube defects (NTDs) are among major NTDs, due to their severity and relatively high incidence; in the meanwhile NTDs are also the most effectively preventable BDs to date. In particular, an adequate folic acid (FA) intake reduces both the occurrence and the recurrence of NTDs; FA is the synthetic form of folates, naturally occurring vitamins in a number of foods, especially vegetables. The daily intake of 0.4 mg of FA should be recommended to all women of childbearing age who plan to become pregnant. The Italian Network for Primary Prevention of BDs through FA Promotion has achieved a significant improvement in FA awareness and use in the periconceptional period. Nevertheless, primary prevention of BDs needs to make further progress; the Italian National Centre for Rare Diseases participates in european sureveillance of congenital anomalies (EUROCAT) Joint Action as coordinator of activities on the effectiveness of BDs prevention. Mandatory food fortification with FA has not been introduced in any European country. The health benefits of FA in reducing the risk of NTDs are undisputed; however mechanistic and animal studies suggest a relationship between high FA intakes and increased cancer promotion, while human studies are still inconsistent and inconclusive. A Working Group organized by the European Food Safety Authority pointed out significant uncertainties about fortification safety and the need for more studies; currently, FA intake from fortified foods and supplements should not exceed 1 mg/day in adults. In conclusion, based on up-to-date scientific evidence, the Italian Network strategy pivots on periconceptional supplementation integrated with promotion of healthy eating habits, support to health education, enhancing the role of women in managing life choices about their health and pregnancy and increasing

  1. ILC Beam delivery WG summary: Optics, collimation and background

    Energy Technology Data Exchange (ETDEWEB)

    Angal-Kalinin, D.; Jackson, F.; /Daresbury; Mokhov, N.V.; /Fermilab; Kuroda, S.; /KEK, Tsukuba; Seryi, A.A.; /SLAC

    2006-07-01

    The paper summarizes the work of the Beam Delivery working group (WG4) at Snowmass 2005 workshop, focusing on status of optics, layout, collimation and detector background. The strawman layout with two interaction regions was recommended at the first ILC workshop at KEK in November 2004. Two crossing-angle designs were included in this layout. The design of the ILC BDS has evolved since the first ILC workshop. The progress on the BDS design including the collimation system, and extraction line design have been reviewed and the design issues were discussed during the WG4 sessions at the Snowmass, and are described in this paper.

  2. Beam Delivery WG Summary: Optics, Collimation & Background

    Energy Technology Data Exchange (ETDEWEB)

    Angal-Kalinin, D.; Jackson, F.; /Daresbury; Mokhov, N.V.; /Fermilab; Kuroda, S.; /KEK, Tsukuba; Seryi, A.A.; /SLAC

    2006-01-20

    The presented paper partially summarizes the work of the Beam Delivery working group (WG4) at Snowmass, concentrating on status of optics, layout, collimation, and background. The strawman layout with 2 interaction regions was recommended at the first ILC workshop at KEK in November 2004. Two crossing-angle designs were included in this layout. The design of the ILC BDS has evolved since the first ILC workshop. The progress on the BDS design and extraction line design has been reviewed and the design issues were discussed during the optics and layout session at the Snowmass.

  3. Dalitz plot analysis and branching fraction measurement of D+ and Ds+ -> pi+pi-pi+

    OpenAIRE

    Bediaga, Ignacio

    2000-01-01

    Fermilab fixed target experiment E791 obtained a sample of $1172 \\pm 61$ events of $D^+ \\to \\pi^- \\pi^+ \\pi^+$ and 848 $\\pm 44$ events of $D_s^+ \\to \\pi^- \\pi^+ \\pi^+$ decays. We find respectively $B (D^+ \\to \\pi^- \\pi^+ \\pi^+) / B (D^+ \\to K^- \\pi^+ \\pi^+) = 0.0311 \\pm 0.0018 ^ {+0.0016}_{-0.0026}$ and $B(D_s^+ \\to \\pi^+ \\pi^- \\pi^+) / B(D_s^+ \\to \\phi \\pi^+) = 0.245 \\pm 0.028^{+0.019}_{-0.012}$. Using a coherent amplitude analysis to fit the Dalitz plot of the $D^+ \\to \\pi^- \\pi^+ \\pi^+$ de...

  4. China Satellite Navigation Conference

    CERN Document Server

    Liu, Jingnan; Fan, Shiwei; Wang, Feixue

    2016-01-01

    These Proceedings present selected research papers from CSNC2016, held during 18th-20th May in Changsha, China. The theme of CSNC2016 is Smart Sensing, Smart Perception. These papers discuss the technologies and applications of the Global Navigation Satellite System (GNSS), and the latest progress made in the China BeiDou System (BDS) especially. They are divided into 12 topics to match the corresponding sessions in CSNC2016, which broadly covered key topics in GNSS. Readers can learn about the BDS and keep abreast of the latest advances in GNSS techniques and applications.

  5. Physical volcanology, geochemistry and basin evolution of the Ediacaran volcano-sedimentary succession in the Bas Draâ inlier (Ouarzazate Supergroup, Western Anti-Atlas, Morocco)

    Science.gov (United States)

    Karaoui, Brahim; Breitkreuz, Christoph; Mahmoudi, Abdelkader; Youbi, Nasrrddine

    2014-11-01

    New geologic mapping, lithofacies and granulometric analysis, and geochemistry from the volcano-sedimentary successions of the central part of the Bas Draâ inlier, Western Anti-Atlas, constrain the Ediacaran Ouarzazate Supergroup evolution during the post-collisional stage of the Pan-African orogeny. Volcanosedimentary facies analysis is the key aspect of the present contribution. We distinguished sixteen terrestrial volcanosedimentary lithofacies in the Bas Draâ succession (BDS), which reaches a total thickness of 2000 m. BDS evolution can be grouped into four units (Aouinet Aït Oussa I to IV, AO I-AO IV). The earliest volcanic activity produced rhyolitic ignimbrite sheets (AO I), which had been considered as lava flows by previous workers, and which were presumably related to caldera system(s). During AO II, a complex of high-silica andesitic and rhyolitic lavas formed, punctuated by the explosive eruption of a high-temperature silica-rich magma leading to the formation of parataxitic ignimbrite. AO III consists of basalt and andesite lava fields and small explosive, in parts phreatomagmatic volcanic vents. It is dissected by fluvial systems depositing external non-volcanic and local volcanic debris. BDS evolution terminated with the formation of a large SiO2-rich lava dome complex (AO IV), accompanied by small basalt effusive event. Volcanosedimentary facies analysis infers that the BDS evolved in a continental extensional setting developing in a low topography under humid paleoclimatic conditions. Alteration textures are dominated by a piemontite-calcite-albite-quartz (+ iron oxides) assemblage. Chemical analysis of BDS volcanic and subvolcanic rocks belongs to high-k calc-alkaline and alkali-calcic to alkaline magmatic trend typical for a post-collision setting. Trace elements spidergrams show a pattern typical for subduction-related suites of orogenic belts. REE patterns show moderate enrichment in LREE relative to flat HREE, with strong negative Eu

  6. Two Na+ and Cl- Hyperaccumulators of the Chenopodiaceae

    Institute of Scientific and Technical Information of China (English)

    Ke-Fu ZHAO; Hai FAN; Jie SONG; Ming-Xia SUN; Bao-Zeng WANG; Sheng-Qiang ZHANG; I. A. UNGAR

    2005-01-01

    The authors found five sodium (Na+) and chloride (Cl-) hyperaccumulating halophytes in the Temperate Desert of Xinjiang, China and studied two of them (Suaeda salsa (L.) Pall. and Kalidium folium (Pall.) Moq.). K. folium and S. salsa had a NaCl content of 32.1% and 29.8%, respectively, on a dry weight basis. X-ray microanalysis of the Na+ in the vacuole, apoplasts and cytoplasm of the two plants indicated a ratio of 7.3:5.6:1.0 in K. folium and 7.3:6.6:1.0 in S. salsa. These data show that K. folium and S. salsa both have a high Na+ and Cl-accumulating capacity, which is related to high activity oftonoplast H+-ATPase and H+-PPase.

  7. Myalgic encephalomyelitis: International Consensus Criteria

    OpenAIRE

    Carruthers, B M; van de Sande, M I; De Meirleir, K L; Klimas, N G; Broderick, G; MITCHELL, T; Staines, D.; Powles, A C P; Speight, N; Vallings, R; Bateman, L; Baumgarten-Austrheim, B; Bell, D. S.; N. Carlo-Stella; Chia, J

    2011-01-01

    Carruthers BM, van de Sande MI, De Meirleir KL, Klimas NG, Broderick G, Mitchell T, Staines D, Powles ACP, Speight N, Vallings R, Bateman L, Baumgarten-Austrheim B, Bell DS, Carlo-Stella N, Chia J, Darragh A, Jo D, Lewis D, Light AR, Marshall-Gradisbik S, Mena I, Mikovits JA, Murovska M, Pall ML, Stevens S (Independent, Vancouver, BC, Canada; Independent, Calgary, AB, Canada; Department of Physiology and Medicine, Vrije University of Brussels, Himmunitas Foundation, Brussels, Belgium; Departm...

  8. Kui video võiks tappa... : noppeid Prantsuse-Balti ja Põhjamaade meediakunsti festivalilt / Anders Härm

    Index Scriptorium Estoniae

    Härm, Anders, 1977-

    1998-01-01

    Festivali 'offline@online' kuraatorid Raivo Kelomees, Tiia Johannson. Pierre Yves Clouini videotest, Palle Torssoni arvutimängul Duke Nukem 3D baseeruvast tööst. Eesti kunstnikest on Duke Nukem'it kasutanud Lennart Mänd, Mart Viljus. Kanada kuraatori Stephen Kovatsi rahvusvahelisest projektist 'Ostranenie'. Andras Solymoni, Natalia Borissova, Olli Mannerkoski töödest. Lev Manovichi püstitatud küsimusest interface'ist

  9. Is the Air Handling Capability of the Quadrox D Pump Dependent within an ECMO Circuit? An In Vitro Study

    OpenAIRE

    Gill, Martin C.; Dando, Hayden; Dittmer, John

    2010-01-01

    The occurrence of gaseous microemboli (GME) within the extracorporeal membrane oxygenation circuit is largely overlooked, as are methods to ameliorate this occurrence. We aimed to determine if the air handling capability of the Quadrox D oxygenator was dependent upon whether it was used in conjunction with a centrifugal or roller pump; and if application of a Pall air eliminating filter (AEF) would prevent circuit air introduction from intravenous infusions. Using a blood primed circuit 1 mL ...

  10. Ecological and morphological studies in the hybrid zone between Pinus sibirica and Pinus pumila

    OpenAIRE

    S.N. Goroshkevich; Popov, A. G.; G.V. Vasilieva

    2013-01-01

    In the Baikal Region, there is no phenological isolation between Siberian stone pine (P. sibirica Du Tour) and Siberian dwarf stone pine (P. pumila (Pall.) Regel) since the timing of their 'flowering' coincides. Morphologically intermediate individuals, supposedly natural hybrids,occur not very often. In the west half of Stanovoye upland area four regions were investigated: Barguzinskiy, Baikalskiy, Verchneangarskiy and the Severo-Myiskiy mountain ridges. Interspecific natural hybridization w...

  11. Näitused kunstiakadeemias

    Index Scriptorium Estoniae

    2003-01-01

    EKA galeriis näitusel "Kirju pall" esitavad "krutskilist ökokunsti" rühmitus Puhas Rõõm, Mart Viljus, Anu Vahtra, Maris Mändel, Katrin Tees, Reimo Võsa-Tangsoo, Erki Kasemets, Raivo Hool. Aula fuajees näeb Jaak Soansi juhendamisel valminud skulptuuriosakonna õppetöid, valdavalt poliitikute skulptuurportreid. Osalevad Kristiina Järvelaid, Jelena Levtshenkova, Rene Reinumäe, Kaisa Uusoksa, Marju Vaher

  12. Effects of Yoga training on Personality of school students

    OpenAIRE

    Jayanti Semwal; Ruchi Juyal; Surekha Kishore; S D Kandpal

    2014-01-01

    Background: Personality is not only the physical and mental aspect but also the behaviour or adjustment to the surroundings of an individual. It develops gradually from the childhood –adulthood & may affect or gets influenced by various factors like genetic, social and environmental. Adolescent period is the best time to shape & determine ones destiny. We can channelize their energy in a right direction to make them a responsible human being. Yoga is one intervention mentioned by Pall...

  13. What matters most for end-of-life care? Perspectives from community-based palliative care providers and administrators

    OpenAIRE

    Mistry, Bina; Bainbridge, Daryl; Bryant, Deanna; Tan Toyofuku, Sue; Seow, Hsien

    2015-01-01

    Objectives There has been little research conducted to understand the essential meaning of quality, community-based, end-of-life (EOL) care, despite the expansion of these services. The purpose of this study was to define what matters most for EOL care from the perspective of a diverse range of palliative care providers in the community who have daily encounters with death and dying. Methods We used interviews to explore the perceptions of providers and administrators from 14 specialised pall...

  14. Complete robotic inspection line using PC-based control, supervision and parameterization software

    OpenAIRE

    Norberto Pires, J.; Paulo, Sérgio

    2005-01-01

    Non-flat ceramic products, like toilets and bidets, are fully inspected at the end of the production process, to search for structural, surface and functional defects. Ceramic pieces are transported to the inspection lines assembled in pallets, carried by electro-mechanical fork-lifters or automatic guided vehicles. Pallets need to be disassembled, while feeding with the inspection lines where human operators execute the inspection tasks. Also, the pieces that pass inspection need to be palle...

  15. Comercialización de semillas (variedades e híbridos) importadas de pimentón Capsicum annuum L en Colombia en el periodo enero 1990-agosto 1994

    OpenAIRE

    Lema Nuñez Rosario M.

    1996-01-01

    <p>All the companies that produce varieties of paprika are North American, and due to the strong economic force of 4 or 5, dominate the market. These oligopolies diferenciate the seeds in quality, brand and packaging and in this way restrict other new companies entering the market. Reputable brands of quality (Petoseed, Asgrow and Rogers NK) are the sole producers of hybrid seeds. The difference in price of befween the hybrid paprika seed and the Californian wonder type is substantial. ...

  16. Seed Protein Variations of Salicornia L. and Allied Taxa in Turkey

    OpenAIRE

    A.E. Yaprak; YURDAKULOL, E

    2007-01-01

    Electrophoretic seed protein patterns of a number of accessions of Salicornia europaea L. sl., S. prostrata Palas, S. fragilis P.W. Ball and Tutin, Sarcocornia fruticosa (L.) A. J. Scott, Sarcocornia perennis (Miller.) A. J. Scott, Arthrocnemum glaucum (Del.) Ung.-Sternb., Microcnemum coralloides (Loscos and Pardo) subsp. anatolicum Wagenitz and Halocnemum strobilaceum (Pall.) Bieb. were electrophoretically analysed on SDS-PAGE. In total 48 different bands were identified. The obtained data h...

  17. The Leaf-Beetles (Coleoptera, Chrysomelidae) Feed On Some Weeds In Tokat Province

    OpenAIRE

    Çam, Halit; ATAY, Turgut

    2004-01-01

    This study was carried out to determine the leaf-beetles (Coleoptera, Chrysomelidae) which causes extensive damage on weeds in the vicinity of Tokat, Turkey. Total 9 taxa including 4 species of Chrysomelinae, 1 species of Clytrinae, 1 species of Criocerinae, 2 species of Alticinae and 1 species of Cassidinae were found to be destructive on different weed species. These species were; Entomoscelis adonidis (Pall.) on Sinapis arvensis L., Gastrophysa polygoni (L.) on Polygonum convolvulus L. an...

  18. Løkke lykkes

    DEFF Research Database (Denmark)

    Bengtsson, Mette

    2011-01-01

    Næsten alle er enige: Statsministerens nytårstale var stærk. Lars Løkke Rasmussen er ikke en mand, der normalt høster ros som den store taler, men hans nytårstale lykkes retorisk. Talen giver mindelser om Reagans slogans, Voltaires ordsprog, Krønikens Palle From – og så har den suspense. Men...

  19. Accumulation of moisture and soil erosion in the territory of social vole ( Microtus socialis) settlements in the northern Caspian Lowland

    Science.gov (United States)

    Bykov, A. V.; Kolesnikov, A. V.; Kulakova, N. Yu.; Shabanova, N. P.

    2008-08-01

    In the clay semidesert of the Caspian Lowland, the surface runoff is transformed to soil runoff due to the presence of a system of social vole ( Microtus socialis Pall.) passageways in the soils that promotes the retention of soil moisture and prevents the development of soil erosion. A quantitative assessment of this process is given. We describe the mechanism of intense soil erosion arising after the disturbance of vole underground passageways responsible for the formation of specific relief elements and plant communities.

  20. Cellular Metabolic Network Analysis: Discovering Important Reactions in Treponema pallidum

    OpenAIRE

    Xueying Chen; Min Zhao; Hong Qu

    2015-01-01

    T. pallidum, the syphilis-causing pathogen, performs very differently in metabolism compared with other bacterial pathogens. The desire for safe and effective vaccine of syphilis requests identification of important steps in T. pallidum's metabolism. Here, we apply Flux Balance Analysis to represent the reactions quantitatively. Thus, it is possible to cluster all reactions in T. pallidum. By calculating minimal cut sets and analyzing topological structure for the metabolic network of T. pall...

  1. Comparison of anatomical characteristics of leaves and flowers of Crataegus and some species of Rosaceae family

    OpenAIRE

    V.A. Kiryanova; E.U. Babaeva

    2014-01-01

    The present work shows the results of microscopy of Crataegus sanguinea Pall. leaves with flowers (Crataegi flores cum folia), which is considered as a perspective form of medicinal raw material, and the hypothetical plant adulterants – Amelanchier ovalis Medik., Prunus subgen. Cerasus (Mill.) A. Gray, Pyrus communis L., Aronia melanocarpa (Michx.) Elliott (Rosaceae). Parts of leaves and flowers of stated plants were subjected to anatomical investigation and comparative studies. Microscopical...

  2. Sequence Classification: 894022 [TMBETA-GENOME[Archive

    Lifescience Database Archive (English)

    Full Text Available Non-TMB Non-TMH Non-TMB Non-TMB Non-TMB Non-TMB >gi|6324409|ref|NP_014478.1| Bacterially-derived ... sulfatase required for use ... of alkyl- and aryl-sulfates as sulfur sources; Bds ...

  3. Clinical Implications of DSM-IV Subtyping of Bipolar Disorders in Referred Children and Adolescents

    Science.gov (United States)

    Masi, Gabriele; Perugi, Giulio; Millepiedi, Stefania; Mucci, Maria; Pari, Cinzia; Pfanner, Chiara; Berloffa, Stefano; Toni, Cristina

    2007-01-01

    Objective: According to DSM-IV, bipolar disorders (BDs) include four subtypes, BD I, BD II, cyclothymic disorder, and BD not otherwise specified (NOS). We explore the clinical implications of this subtyping in a naturalistic sample of referred youths with BD I, BD II, and BD-NOS. Method: The sample consisted of 217 patients, 135 males and 82…

  4. Relation between Brown Dwarfs and Exoplanets

    CERN Document Server

    Torres, Lauren Melissa Flor; Schröeder, Klauss-Peter; Caretta, César A; Jack, Dennis

    2016-01-01

    One of the most debated subjects in Astronomy since the discovery of exoplanets is how can we distinguish the most massive of such objects from very-low mass stars like Brown Dwarfs (BDs)? We have been looking for evidences of a difference in physical characteristics that could be related to different formation processes. Using a new diagnostic diagram that compares the baryonic gravitational potential (BGP) with the distances from their host stars, we have classified a sample of 355 well-studied exoplanets according to their possible structures. We have then compared the exoplanets to a sample of 87 confirmed BDs, identifying a range in BGP that could be common to both objects. By analyzing the mass-radius relations (MRR) of the exoplanets and BDs in those different BGP ranges, we were able to distinguish different characteristic behaviors. By comparing with models in the literature, our results suggest that BDs and massive exoplanets might have similar structures dominated by liquid metallic hydrogen (LMH).

  5. The use of skin surface electropotentials for breast cancer detection--preliminary clinical trial results obtained using the biofield diagnostic system.

    Science.gov (United States)

    Sree, Subbhuraam Vinitha; Ng, E Y K; Kaw, G; U, Rajendra Acharya; Chong, B K

    2011-02-01

    The purpose of this study is to evaluate the efficiency of the Biofield Diagnostic System (BDS) as an adjunct to established diagnostic techniques such as mammography and ultrasound in differentiating benign and malignant breast lesions. The clinical trial was conducted at the Tan Tock Seng hospital, Singapore. 103 women scheduled for mammography and/or ultrasound tests participated in the study. The BDS test recorded a sensitivity of 100%, specificity of 97.6%, and an accuracy of 98.1%. The area under the ROC curve was 0.988 which was slightly lower than that of ultrasound (0.994) and slightly higher than that of mammography (0.951). The BDS test has demonstrated high sensitivity and specificity values in the studied population. The accuracy is also comparable to that of diagnostic techniques like mammography and ultrasound. Thus, it is evident that BDS can be a fast and reliable adjunct tool for getting a secondary opinion on lesions with indeterminate mammographic and sonographic results. PMID:20703583

  6. Bubble detector's evaluation for neutron field measurement in a very known source

    Energy Technology Data Exchange (ETDEWEB)

    Ramalho, Eduardo; Silva, Ademir X. da, E-mail: ademir@nuclear.ufrj.b, E-mail: jdantas@con.ufrj.b [Coordenacao dos Programas de Pos-Graduacao de Engenharia (PEN/COPPE/UFRJ), RJ (Brazil). Programa de Engenharia Nuclear; Reina, Luiz, E-mail: reina@ien.gov.b [Instituto de Engenharia Nuclear (IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil); Facure, Alessandro, E-mail: facure@cnen.gov.b [Comissao Nacional de Energia Nuclear (CNEN), Rio de Janeiro, RJ (Brazil)

    2011-07-01

    Measurements on neutron fields, mainly for dosimetric purposes, have been a major concern for ionizing radiation workers, because of the radiation protection issues. The present work aims to study the using of bubble detectors in neutron dosimetry and the Bubble Detector Spectrometer (BDS) was chosen for this task. Several experiments were performed in order to obtain spectra from such devices and their respective analysis and then they were compared to those which were obtained by other ways. An Am-Be calibration neutron source from Instituto de Radioprotecao e Dosimetria/Comissao Nacional de Energia Nuclear (IRD/CNEN) was used and its spectrum was compared to the one obtained by BDS. The possibility of the use of such devices as ambient dosimeters was also evaluated. Despite the uncertainties, especially in the lowest energy thresholds, the spectrum from BDS is in good agreement with the known ones and the use of BDS as a dosimeter demands a more detailed study due to some characteristics of the Am-Be source that produce high uncertainties in low energy thresholds. (author)

  7. The birds of the Republic of Colombia: (Segunda entrega: Accipitridae - Picidae

    Directory of Open Access Journals (Sweden)

    Meyer de Schauensee Rodolphe

    1949-10-01

    Full Text Available Figures given in parentheses are wing measurements from Swann's Monogr. Bds. Prey. Those which do not appear in parentheses are from other published sources, or in most cases they are extreme measurements taken from Colombian specimens by Professor Dugand.

  8. BeiDou Time Transfer With the Standard CGGTTS.

    Science.gov (United States)

    Huang, Wei; Defraigne, Pascale

    2016-07-01

    The R2CGGTTS software tool developed at the Royal Observatory of Belgium (ROB) to provide clock solutions in the standard Common GNSS Generic Time Transfer Standard (CGGTTS) has been extended to BeiDou Navigation Satellite System (BDS). The BDS includes satellites in three different orbits: 1) Medium Earth Orbit (MEO); 2) Inclined Geosynchronous Satellite Orbit (IGSO); and 3) Geostationary Earth Orbit (GEO). This paper presents first results obtained with this upgraded software, and a comparison between common view (CV) time transfer solutions obtained with either BDS, or GPS or Galileo. These preliminary results indicate that the BeiDou MEO satellites give time transfer results with a higher noise than the GPS results. This additional noise is shown to be due to some elevation-dependent delay in the BDS code measurements. Some biases were furthermore pointed out between the CV results obtained with the different BeiDou MEO satellites when the receivers used in the two stations are of different make. These biases may reach some nanoseconds, and find most probably their origin in the receiver hardware or firmware. It is shown additionally that using the BeiDou IGSO satellites and the GEO satellites, although increasing the number of observations, especially in the Asia-Pacific region, introduces a significant time transfer noise in the CV results. PMID:26766373

  9. Importance of clinical posting for awareness on bio-medical waste in medical and paramedical students

    Directory of Open Access Journals (Sweden)

    Jemil S Makadia

    2014-10-01

    Full Text Available Background: The management of health care waste is the subject of considerable concern to public health. Unscientific disposal of health care waste may lead to the transmission of communicable disease which is a risk for health care professionals. Objective: The main objective of this study was to assess the awareness in the medical and paramedical students about bio-medical waste (BMW hazards and management and to see the impact of clinical posting in knowledge regarding BMW handling. Materials and Methods: This was a cross-sectional type of study. A total of 240 subjects was enrolled, 60 each from 1 st year students of MBBS, BDS, nursing, and MLT. They were interviewed for health care waste management practices. Results: Study shows overall awareness regarding BMW in nursing and MLT students were better than MBBS and BDS students. We found that about the infection like HIV almost all the students were equally aware but awareness about hepatitis B infection was more in MBBS and BDS students and also in nursing students compared with MLT students. All the students from four groups were almost vaccinated for tetanus toxoid but only 50% students were vaccinated for hepatitis B. Conclusion: The nursing and MLT students comparatively were having better knowledge and attitude than BDS and MBBS students in many aspects. However, overall knowledge of 1 st year students from all the groups was not satisfactory and number of students those who were vaccinated for hepatitis B was also low which put them at risk.

  10. Early-Life Stress Perturbs Key Cellular Programs in the Developing Mouse Hippocampus.

    Science.gov (United States)

    Wei, Lan; Hao, Jin; Lacher, Richard K; Abbott, Thomas; Chung, Lisa; Colangelo, Christopher M; Kaffman, Arie

    2015-01-01

    Conflicting reports are available with regard to the effects of childhood abuse and neglect on hippocampal function in children. While earlier imaging studies and some animal work have suggested that the effects of early-life stress (ELS) manifest only in adulthood, more recent studies have documented impaired hippocampal function in maltreated children and adolescents. Additional work using animal modes is needed to clarify the effects of ELS on hippocampal development. In this regard, genomic, proteomic, and molecular tools uniquely available in the mouse make it a particularly attractive model system to study this issue. However, very little work has been done so far to characterize the effects of ELS on hippocampal development in the mouse. To address this issue, we examined the effects of brief daily separation (BDS), a mouse model of ELS that impairs hippocampal-dependent memory in adulthood, on hippocampal development in 28-day-old juvenile mice. This age was chosen because it corresponds to the developmental period in which human imaging studies have revealed abnormal hippocampal development in maltreated children. Exposure to BDS caused a significant decrease in the total protein content of synaptosomes harvested from the hippocampus of 28-day-old male and female mice, suggesting that BDS impairs normal synaptic development in the juvenile hippocampus. Using a novel liquid chromatography multiple reaction monitoring mass spectrometry (LC-MRM) assay, we found decreased expression of many synaptic proteins, as well as proteins involved in axonal growth, myelination, and mitochondrial activity. Golgi staining in 28-day-old BDS mice showed an increase in the number of immature and abnormally shaped spines and a decrease in the number of mature spines in CA1 neurons, consistent with defects in synaptic maturation and synaptic pruning at this age. In 14-day-old pups, BDS deceased the expression of proteins involved in axonal growth and myelination, but did not

  11. Designing and Validating Ternary Pd Alloys for Optimum Sulfur/Carbon Resistance in Hydrogen Separation and Carbon Capture Membrane Systems Using High-Throughput Combinatorial Methods

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, Amanda; Zhao, Hongbin; Hopkins, Scott

    2014-09-30

    This report summarizes the work completed under the U.S. Department of Energy Project Award No.: DE-FE0001181 titled “Designing and Validating Ternary Pd Alloys for Optimum Sulfur/Carbon Resistance in Hydrogen Separation and Carbon Capture Membrane Systems Using High-Throughput Combinatorial Methods.” The project started in October 1, 2009 and was finished September 30, 2014. Pall Corporation worked with Cornell University to sputter and test palladium-based ternary alloys onto silicon wafers to examine many alloys at once. With the specialized equipment at Georgia Institute of Technology that analyzed the wafers for adsorbed carbon and sulfur species six compositions were identified to have resistance to carbon and sulfur species. These compositions were deposited on Pall AccuSep® supports by Colorado School of Mines and then tested in simulated synthetic coal gas at the Pall Corporation. Two of the six alloys were chosen for further investigations based on their performance. Alloy reproducibility and long-term testing of PdAuAg and PdZrAu provided insight to the ability to manufacture these compositions for testing. PdAuAg is the most promising alloy found in this work based on the fabrication reproducibility and resistance to carbon and sulfur. Although PdZrAu had great initial resistance to carbon and sulfur species, the alloy composition has a very narrow range that hindered testing reproducibility.

  12. Profile Septa cut out condensate crud

    International Nuclear Information System (INIS)

    Secondary side corrosion is a major factor leading to steam generator tube plugging. Large quantities of steam generator sludge can harden, prolonging system maintenance during an outage. However, eliminating the ingress of solids to the PWR steam generators can reduce the need for sludge lancing and increase the life of the steam generator tubes. The Pall Corporation has developed an improved filter demineralizer septum for retrofitting traditional yarn-wound elements without having to modify hardware. In November 1990, operators at Turkey Point installed 496 2in x 70in Pall's Profile Septa in one of the four filter demineralizer vessels on unit 3. After installation of the Profile Septa, samples of filter influent and effluent were taken and analyzed over a one-month period - these showed a particulate removal rate of 96-99%. Contaminant analysis by Pall Corporation identified the vast majority of particulates to be iron oxides. This is as was expected, since Turkey Point has titanium condenser tubes which reduce the source of copper oxides. The success of Profile Septa at Turkey Point has encouraged the other utilities to look at using the septa at their own plants. The cost for these retrofits would be recouped through savings in maintenance costs, due to faster steam generator lancing (fewer solids), reduced radiation exposure and, ultimately, longer steam generator life. (author)

  13. New models and predictions for Brownian coagulation of non-interacting spheres.

    Science.gov (United States)

    Kelkar, Aniruddha V; Dong, Jiannan; Franses, Elias I; Corti, David S

    2013-01-01

    The classical steady-state Smoluchowski model for Brownian coagulation is evaluated using Brownian Dynamics Simulations (BDS) as a benchmark. The predictions of this approach compare favorably with the results of BDS only in the dilute limit, that is, for volume fractions of φ≤5×10(-4). From the solution of the more general unsteady-state diffusion equation, a new model for coagulation is developed. The resulting coagulation rate constant is time-dependent and approaches the steady-state limit only at large times. Moreover, in contrast to the Smoluchowski model, this rate constant depends on the particle size, with the transient effects becoming more significant at larger sizes. The predictions of the unsteady-state model agree well with the BDS results up to volume fractions of about φ=0.1, at which the aggregation half-time predicted by the Smoluchowski model is five times that of the BDS. A new procedure to extract the aggregation rate constant from simulation results based on this model is presented. The choice of the rate constant kernel used in the population balance equations for complete aggregation is also evaluated. Extension of the new model to a variable rate constant kernel leads to increased accuracy of the predictions, especially for φ≤5×10(-3). This size-dependence of the rate constant kernel affects particularly the predictions for initially polydisperse sphere systems. In addition, the model is extended to account in a novel way for both short-range viscous two-particle interactions and long-range many-particle Hydrodynamic Interactions (HI). Predictions including HI agree best with the BDS results. The new models presented here offer accurate and computationally less-intensive predictions of the coagulation dynamics while also accounting for hydrodynamic coupling. PMID:23036339

  14. Intracellular targeting of mercaptoundecahydrododecaborate (BSH) to malignant glioma by transferrin-PEG liposomes for boron neutron capture therapy (BNCT)

    International Nuclear Information System (INIS)

    Malignant glioma is one of the most difficult tumor to control with usual therapies. In our institute, we select boron neutron capture therapy (BNCT) as an adjuvant radiation therapy after surgical resection. This therapy requires the selective delivery of high concentration of 10B to malignant tumor tissue. In this study, we focused on a tumor-targeting 10B delivery system (BDS) for BNCT that uses transferrin-conjugated polyethylene-glycol liposome encapsulating BSH (TF-PEG liposome-BSH) and compared 10B uptake of the tumor among BSH, PEG liposome-BSH and TF-PEG liposome-BSH. In vitro, we analyzed 10B concentration of the cultured human U87Δ glioma cells incubated in medium containing 20 μg 10B/ml derived from each BDS by inductively coupled plasma atomic emission spectrometry (ICP-AES). In vivo, human U87Δ glioma-bearing nude mice were administered with each BDS (35mg 10B/kg) intravenously. We analyzed 10B concentration of tumor, normal brain and blood by ICP-AES. The TF-PEG liposome-BSH showed higher absolute concentration more than the other BDS. Moreover, TF-PEG liposome-BSH decreased 10B concentration in blood and normal tissue while it maintained high 10B concentration in tumor tissue for a couple of days. This showed the TF-PEG liposome-BSH caused the selective delivery of high concentration of 10B to malignant tumor tissue. The TF-PEG liposome-BSH is more potent BDS for BNCT to obtain absolute high 10B concentration and good contrast between tumor and normal tissue than BSH and PEG liposome-BSH. (author)

  15. Precise orbit determination for quad-constellation satellites at Wuhan University: strategy, result validation, and comparison

    Science.gov (United States)

    Guo, Jing; Xu, Xiaolong; Zhao, Qile; Liu, Jingnan

    2016-02-01

    This contribution summarizes the strategy used by Wuhan University (WHU) to determine precise orbit and clock products for Multi-GNSS Experiment (MGEX) of the International GNSS Service (IGS). In particular, the satellite attitude, phase center corrections, solar radiation pressure model developed and used for BDS satellites are addressed. In addition, this contribution analyzes the orbit and clock quality of the quad-constellation products from MGEX Analysis Centers (ACs) for a common time period of 1 year (2014). With IGS final GPS and GLONASS products as the reference, Multi-GNSS products of WHU (indicated by WUM) show the best agreement among these products from all MGEX ACs in both accuracy and stability. 3D Day Boundary Discontinuities (DBDs) range from 8 to 27 cm for Galileo-IOV satellites among all ACs' products, whereas WUM ones are the largest (about 26.2 cm). Among three types of BDS satellites, MEOs show the smallest DBDs from 10 to 27 cm, whereas the DBDs for all ACs products are at decimeter to meter level for GEOs and one to three decimeter for IGSOs, respectively. As to the satellite laser ranging (SLR) validation for Galileo-IOV satellites, the accuracy evaluated by SLR residuals is at the one decimeter level with the well-known systematic bias of about -5 cm for all ACs. For BDS satellites, the accuracy could reach decimeter level, one decimeter level, and centimeter level for GEOs, IGSOs, and MEOs, respectively. However, there is a noticeable bias in GEO SLR residuals. In addition, systematic errors dependent on orbit angle related to mismodeled solar radiation pressure (SRP) are present for BDS GEOs and IGSOs. The results of Multi-GNSS combined kinematic PPP demonstrate that the best accuracy of position and fastest convergence speed have been achieved using WUM products, particularly in the Up direction. Furthermore, the accuracy of static BDS only PPP degrades when the BDS IGSO and MEO satellites switches to orbit-normal orientation

  16. Executive summary of the workshop on polarisation and beam energy measurement at the ILC

    International Nuclear Information System (INIS)

    This note summarizes the results of the ''Workshop on Polarisation and Beam Energy Measurements at the ILC'', held at DESY (Zeuthen) April 9-11 2008. The topics for the workshop included (i) physics requirements, (ii) polarised sources and low energy polarimetry, (iii) BDS polarimeters, (iv) BDS energy spectrometers, and (v) physics-based measurements of beam polarisation and beam energy from collider data. Discussions focused on the current ILC baseline programme as described in the Reference Design Report (RDR), which includes physics runs at beam energies between 100 and 250 GeV, as well as calibration runs on the Z-pole. Electron polarisation of Pe- >or similar 80% and positron polarisation of Pe+ >or similar 30% are part of the baseline configuration of the machine. Energy and polarisation measurements for ILC options beyond the baseline, including Z-pole running and the 1 TeV energy upgrade, were also discussed. (orig.)

  17. Biocatalytic desulfurization of diesel oil in an air-lift reactor with immobilized Gordonia nitida CYKS1 cells.

    Science.gov (United States)

    Lee, In Su; Bae, Hee-Sung; Ryu, Hee Wook; Cho, Kyung-Suk; Chang, Yong Keun

    2005-01-01

    A new type of air-lift reactor with immobilized Gordonia nitida CYKS1 cells on a fibrous support was designed and used for the biocatalytic desulfurization (BDS) of diesel oil. Its performance was evaluated at different phase ratios of the oil to the aqueous medium (or oil phase fractions) and different sucrose concentrations. When the reaction mixture contained 10% diesel oil (v/v), 61-67% of sulfur was removed as the sulfur content decreased from 202-250 to 76-90 mg L(-1) in 72 h. The sulfur content did not decrease any further because the remaining sulfur compounds were recalcitrant to BDS. During the desulfurization, the strain CYKS1 consumed hydrocarbons in the diesel oil, mainly n-alkanes with 10-26 carbons, as carbon source even though an easily available carbon source, sucrose, was supplied. PMID:15932256

  18. MHV amplitudes for 3→3 gluon scattering in Regge limit

    International Nuclear Information System (INIS)

    We calculate corrections to the BDS formula for the six-particle planar MHV amplitude for the gluon transition 3 → 3 in the multi-Regge kinematics for the physical region, in which the Regge pole ansatz is not valid. The remainder function at two loops is obtained by an analytic continuation of the expression derived by Goncharov, Spradlin, Vergu and Volovich to the kinematic region described by the Mandelstam singularity exchange in the crossing channel. It contains both the imaginary and real contributions being in agreement with the BFKL predictions. The real part of the three loop expression is found from a dispersion-like all-loop formula for the remainder function in the multi-Regge kinematics derived by one of the authors. We also make a prediction for the all-loop real part of the remainder function multiplied by the BDS phase, which can be accessible through calculations in the regime of the strong coupling constant. (orig.)

  19. Monitoring Network and Interfacial Healing Processes by Broadband Dielectric Spectroscopy: A Case Study on Natural Rubber.

    Science.gov (United States)

    Hernández, M; Grande, A M; van der Zwaag, S; García, S J

    2016-04-27

    Broadband dielectric spectroscopy (BDS) is introduced as a new and powerful technique to monitor network and macroscale damage healing in an elastomer. For the proof of concept, a partially cured sulfur-cured natural rubber (NR) containing reversible disulfides as the healing moiety was employed. The forms of damage healed and monitored were an invisible damage in the rubber network due to multiple straining and an imposed macroscopic crack. The relaxation times of pristine, damaged, and healed samples were determined and fitted to the Havriliak-Negami equation to obtain the characteristic polymer parameters. It is shown that seemingly full mechanical healing occurred regardless the type of damage, while BDS demonstrates that the polymer architecture in the healed material differs from that in the original one. These results represent a step forward in the understanding of damage and healing processes in intrinsic self-healing polymer systems with prospective applications such as coatings, tires, seals, and gaskets. PMID:27057588

  20. AcEST: BP920194 [AcEST

    Lifescience Database Archive (English)

    Full Text Available 165 >sp|O62618|MK14A_DROME Mitogen-activated protein kinase 14A OS=Drosophila melanogaster GN=Mpk2 PE=1 SV=1... OS=Brad... 33 5.5 tr|A5BDS4|A5BDS4_VITVI Putative uncharacterized protein OS=Vitis... 33 7.2 tr|B6QHF4|B6QHF4_PENMA 60S ribosome bio...T Sbjct: 595 RSPIEYIKLLT 605 >tr|B6QHF4|B6QHF4_PENMA 60S ribosome biogenesis protein Mak11, putative OS=Peni...rot sp_hit_id Q6AJ23 Definition sp|Q6AJ23|SYC_DESPS Cysteinyl-tRNA synthetase OS=Desulfotalea psychrophila Align length 74 Score (bi...ller, and David J. Lipman (1997), Gapped BLAST and PSI-BLAST: a new generation of protein database search prog

  1. Barium titanate nanocomposite capacitor FY09 year end report.

    Energy Technology Data Exchange (ETDEWEB)

    Stevens, Tyler E.; DiAntonio, Christopher Brian; Yang, Pin; Chavez, Tom P.; Winter, Michael R.; Monson, Todd C.; Roesler, Alexander William; Fellows, Benjamin D.

    2009-11-01

    This late start RTBF project started the development of barium titanate (BTO)/glass nanocomposite capacitors for future and emerging energy storage applications. The long term goal of this work is to decrease the size, weight, and cost of ceramic capacitors while increasing their reliability. Ceramic-based nanocomposites have the potential to yield materials with enhanced permittivity, breakdown strength (BDS), and reduced strain, which can increase the energy density of capacitors and increase their shot life. Composites of BTO in glass will limit grain growth during device fabrication (preserving nanoparticle grain size and enhanced properties), resulting in devices with improved density, permittivity, BDS, and shot life. BTO will eliminate the issues associated with Pb toxicity and volatility as well as the variation in energy storage vs. temperature of PZT based devices. During the last six months of FY09 this work focused on developing syntheses for BTO nanoparticles and firing profiles for sintering BTO/glass composite capacitors.

  2. Measurement of Ds+ to mu+ nu and the Decay constant f_Ds

    CERN Document Server

    Artuso, M; Butt, J; Li, J; Menaa, N; Mountain, R; Nisar, S; Randrianarivony, K; Redjimi, R; Sia, R; Skwarnicki, T; Stone, S; Wang, J C; Zhang, K; Csorna, S E; Bonvicini, G; Cinabro, D; Dubrovin, M; Lincoln, A; Asner, D M; Edwards, K W; Briere, R A; Brock, I; Chen, J; Ferguson, T; Tatishvili, G T; Vogel, H; Watkins, M E; Rosner, J L; Adam, N E; Alexander, J P; Berkelman, K; Cassel, D G; Duboscq, J E; Ecklund, K M; Ehrlich, R; Fields, L; Gibbons, L; Gray, R; Gray, S W; Hartill, D L; Heltsley, B K; Hertz, D; Jones, C D; Kandaswamy, J; Kreinick, D L; Kuznetsov, V E; Mahlke-Krüger, H; Onyisi, P U E; Patterson, J R; Peterson, D; Pivarski, J; Riley, D; Ryd, A; Sadoff, A J; Schwarthoff, H; Shi, X; Stroiney, S; Sun, W M; Wilksen, T; Weinberger, M; Athar, S B; Patel, R; Potlia, V; Yelton, J; Rubin, P; Cawlfield, C; Eisenstein, B I; Karliner, I; Kim, D; Lowrey, N; Naik, P; Sedlack, C; Selen, M; White, E J; Wiss, J; Shepherd, M R; Besson, D; Pedlar, T K; Cronin-Hennessy, D; Gao, K Y; Gong, D T; Hietala, J; Kubota, Y; Klein, T; Lang, B W; Poling, R; Scott, A W; Smith, A; Zweber, P; Dobbs, S; Metreveli, Z V; Seth, K K; Tomaradze, A G; Ernst, J; Severini, H; Dytman, S A; Love, W; Savinov, V; Aquines, O; Li, Z; López, A; Mehrabyan, S S; Méndez, H; Ramírez, J; Huang, G S; Miller, D H; Pavlunin, V; Sanghi, B; Shipsey, I P J; Xin, B; Adams, G S; Anderson, M; Cummings, J P; Danko, I; Napolitano, J; He, Q; Insler, J; Muramatsu, H; Park, C S; Thorndike, E H; Yang, F; Coan, T E; Gao, Y S; Liu, F

    2007-01-01

    We examine e+e- to Ds- Ds*+ or Ds-* Ds+ collisions at 4170 MeV using the CLEO-c detector in order to measure the decay constant f_Ds+. We use the Ds+ to ell+ nu channel, where the ell+ designates either a mu+ or a tau+. Analyzing both modes simultaneously, we determine B(D_s^+ to mu+ nu)= (0.657 +- 0.090 +- 0.028)%, B(D_s^+ to tau+ nu)= (7.1 +- 1.4 +- 0.3)%, and extract f_Ds+ = 282 +- 16 +- 7 MeV. Combining with our previous determination of B(D+ to mu+ nu), we find that the ratio f_Ds+/f_D+ = 1.27 +- 0.12 +- 0.03. (All new results here are preliminary.) We compare with current theoretical estimates.

  3. A novel MOCVD reactor for growth of high-quality GaN-related LED layers

    Science.gov (United States)

    Hu, Shaolin; Liu, Sheng; Zhang, Zhi; Yan, Han; Gan, Zhiyin; Fang, Haisheng

    2015-04-01

    Gallium nitride (GaN), a direct bandgap semiconductor widely used in bright light-emitting diodes (LEDs), is mostly grown by metal-organic chemical vapor deposition (MOCVD) method. A good reactor design is critical for the production of high-quality GaN thin films. In this paper, we presented a novel buffered distributed spray (BDS) MOCVD reactor with vertical gas sprayers and horizontal gas inlets. Experiments based on a 36×2″ BDS reactor were conducted to examine influence of the process parameters, such as the operating pressure and the gas flow rate, on the growth efficiency and on the layer thickness uniformity. Transmission electron microscopy (TEM) and photoluminescence (PL) are further conducted to evaluate quality of the epitaxial layers and to check performance of the reactor. Results show that the proposed novel reactor is of high performance in growing high-quality thin films, including InGaN/GaN multiquantum wells (MQWs) structures.

  4. BFKL Pomeron, Reggeized gluons and Bern-Dixon-Smirnov amplitudes

    Energy Technology Data Exchange (ETDEWEB)

    Bartels, J. [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik; Lipatov, L.N. [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik]|[St. Petersburg Nuclear Physics Institute (Russian Federation); Sabio Vera, A. [CERN, Geneva (Switzerland)

    2008-02-15

    After a brief review of the BFKL approach to Regge processes in QCD and in supersymmetric (SUSY) gauge theories we propose a strategy for calculating the next-to-next-to-leading order corrections to the BFKL kernel. They can be obtained in terms of various cross-sections for Reggeized gluon interactions. The corresponding amplitudes can be calculated in the framework of the effective action for high energy scattering. In the case of N=4 SUSY it is also possible to use the Bern-Dixon-Smirnov (BDS) ansatz. For this purpose the analytic properties of the BDS amplitudes at high energies are investigated, in order to verify their self-consistency. It is found that, for the number of external particles being larger than five, these amplitudes, beyond one loop, are not in agreement with the BFKL approach which predicts the existence of Regge cuts in some physical channels. (orig.)

  5. Detecting Chaos from Agricultural Product Price Time Series

    OpenAIRE

    Xin Su; Yi Wang; Shengsen Duan; Junhai Ma

    2014-01-01

    Analysis of the characteristics of agricultural product price volatility and trend forecasting are necessary to formulate and implement agricultural price control policies. Taking wholesale cabbage prices as an example, a multiple test methodology has been adopted to identify the nonlinearity, fractality, and chaos of the data. The approaches used include the R/S analysis, the BDS test, the power spectra, the recurrence plot, the largest Lyapunov exponent, the Kolmogorov entropy, and the corr...

  6. DOES INCREASING DENTAL EDUCATION IMPROVE THE ORAL HYGIENE STATUS OF DENTAL STUDENTS?

    OpenAIRE

    Purnima V.; Thilagarani; Pramod; Vidyesh Durga; Nitin; Ravishankar; Anil; Amit

    2015-01-01

    OBJECTIVES: The purpose of this study was to assess the impact of increased knowledge acquired by the dental student in preventive aspects of dental education during his curriculum on his own health attitude, oral hygiene and gingival status. METHODS: A total of 240 students pursuing the undergraduate course (B.D.S) at t he New Horizon Dental College and Research Institute, Bilaspur (Chhattisgarh) were recruited for the study and divided into 4 groups based on the ...

  7. Pattern of mRNA expression of β-defensins in basal cell carcinoma

    International Nuclear Information System (INIS)

    Although the human β-defensins hBDs today seem to have diverse functional activities in innate antimicrobial immunity, a few reports also indicated an altered expression of these antimicrobial peptides (AMPs) in tissues of cancers such as oral squamous cell carcinoma. The present work was aimed on the study of hBD gene expression in basal cell carcinoma (BCC) which is the most common cancer in humans. Twenty-two non-ulcerated BCCs (12 nodular type, 10 superficial type) have been analysed for the presence of hBD (1–3) mRNA by quantitative real-time RT-PCR. As controls, non-lesional skin specimens of BCC patients as well as samples of healthy subjects were assessed by RT-PCR. hBD-1 levels in healthy controls and non-lesional skin of BCC patients were significantly (P < 0.05) higher than the levels observed in tumour tissue. Moreover, BCCs showed significantly (P < 0.05) increased mRNA expression of hBD-2 as compared to controls. There was no significant (P > 0.05) difference between lesional mRNA levels for hBD-3 and those levels observed in controls. The mRNA expression of hBDs (1–3) found in nodular and superficial BCCs did not significantly (P > 0.05) differ. The gene expression patterns of hBD-1 and hBD-2 are for the first time shown to be significantly altered in non-ulcerated BCCs as compared to intra-individual and inter-individual controls, respectively. The present findings may indicate that beside the antimicrobial activity of AMPs, hBDs may also play a role in the pathogenesis of BCC. However, functional and immunohistological studies investigating hBDs in patients with BCC are needed to confirm our data

  8. Using $B_{d}^{0}$, $B_{s}^{0}$ Decays at Hadronic B-Factories to Determine CP Angles $\\alpha$ and $\\beta$

    CERN Document Server

    Kim, C S

    1999-01-01

    At the first PPPP workshop, I gave a review talk on physics of B and CP-phases. In my talk, I explained DRG method and our extension to extract CP angles $\\alpha$ and $\\gamma$ from measurements of the decay rates of $B_{d,s}^0 discrete ambiguities are removed, fewer assumptions are necessary, and the method works even if all strong phases vanish. I also talked on several other topics.

  9. Expression and Antimicrobial Function of Beta-Defensin 1 in the Lower Urinary Tract

    OpenAIRE

    Becknell, Brian; Spencer, John David; Carpenter, Ashley R.; Chen, Xi; Singh, Aspinder; Ploeger, Suzanne; Kline, Jennifer; Ellsworth, Patrick; Li, Birong; Proksch, Ehrhardt; Schwaderer, Andrew L.; Hains, David S.; Justice, Sheryl S.; McHugh, Kirk M.

    2013-01-01

    Beta defensins (BDs) are cationic peptides with antimicrobial activity that defend epithelial surfaces including the skin, gastrointestinal, and respiratory tracts. However, BD expression and function in the urinary tract are incompletely characterized. The purpose of this study was to describe Beta Defensin-1 (BD-1) expression in the lower urinary tract, regulation by cystitis, and antimicrobial activity toward uropathogenic Escherichia coli (UPEC) in vivo. Human DEFB1 and orthologous mouse ...

  10. Alday-Maldacena duality and AdS Plateau problem

    OpenAIRE

    Morozov, A.

    2008-01-01

    A short summary of approximate approach to the study of minimal surfaces in AdS, based on solving Nambu-Goto equations iteratively. Today, after partial denunciation of the BDS conjecture, this looks like the only constructive approach to understanding the ways of its possible modification and thus to saving the Alday-Maldacena duality. Numerous open technical problems are explicitly formulated throughout the text.

  11. SELF-MEDICATION AMONG DENTAL UNDERGRADUATE STUDENTS: A GROWING CONCERN

    OpenAIRE

    Suruchi Aditya

    2013-01-01

    Background: Self-medication is an important component of self-care. Though it is widely practiced globally, very few studies have evaluated its pattern and prevalence in dental students.Aim: The study was conducted to compare pattern of self-medication practices between junior and senior dental undergraduate students.Methods: This was a cross-sectional, anonymous, descriptive study with a six month illness recall that evaluated two groups of dental students- Group I: second year BDS students...

  12. Development of RP-HPLC for analysis of human insulin

    OpenAIRE

    Rajan D; Gowda K; Mandal U; Ganesan.M; Bose A; Sarkar A; Pal T

    2006-01-01

    The objective of the present work is to develop a simple and sensitive method for analysis of human insulin injection by using reverse-phase high performance liquid chromatography technique. A reverse-phase high performance liquid chromatography method with UV-detection at room temperature has been developed for the analysis of insulin from formulation. Hypersil BDS C-18 was used as stationary phase, and mobile phase consisted of 60 volume of 1 mmol sodium sulphate and 0.2% triethylami...

  13. Surveying Nepal’s Sexual and Gender Minorities: An Inclusive Approach

    OpenAIRE

    Knight, Kyle

    2014-01-01

    In a recent survey of sexual and gender minorities in Nepal over 60 percent of respondents reported experiencing at least one incident of abuse or discrimination, and over one-third reported discrimination or abuse in three or more public settings. The research methodology and study was implemented through the Williams Institute and the Blue Diamond Society (BDS). The survey utilized Nepal’s inclusion of a third gender category in its national census, the first such attempt in the wo...

  14. Charm and charmonium-like spectroscopy in B decays in Belle

    OpenAIRE

    Aushev, T.

    2009-01-01

    We report measurements of the branching fractions for the decays B->D_s1(2536)+ anti-D(*), where anti-D(*) is anti-D0, D- or D*-, and study of B->X(3872) K with X(3872) decaying to D*0 anti-D0 using a sample of 657 million B anti-B pairs recorded at the Upsilon(4S) resonance with the Belle detector at the KEKB asymmetric-energy e+e- collider.

  15. Simultaneous determination of related substances of oxytetracycline in pharmaceutical semi-solid form by HPLC method

    OpenAIRE

    Violeta Giugiu

    2013-01-01

    Simultaneous determination of oxytetracycline, 4-epioxytetracycline, alpha-apooxytetracycline, tetracycline, beta-apooxytetracycline on C18 columns has been accomplished using a high performance liquid chromatographic method with UV detection. Separation was achieved on a Hypersil BDS RP-C18 column with a mobile phase consisted of acetonitrile-methanol-80 mM dipotassium phosphate pH 7,5 at a flow rate of 0,7 mL min-1. Absorbance measurements were held at 254 nm.

  16. On Chaotic Nature of the Emerging European Forex Markets

    OpenAIRE

    Anoop S. KUMAR; B Kamaiah

    2014-01-01

    This study attempts to analyze the presence deterministic chaos in the forex markets of select European countries namely Bulgaria, Croatia, Czech Republic, Hungary Poland, Romania, Russia, Slovakia and Slovenia. Monthly NEER data ranging from jan-1994 to Dec-2013 is used for the purpose of analysis. A two step methodology is employed where in the first step, non-linear dependence structure in the underlying time series is verified using BDS test. The results show that all the markets under st...

  17. Evaluation of immunogenicity and reactogenicity of recombinant DNA hepatitis B vaccine produced in India

    OpenAIRE

    Hussain, Zahid; Ali, Syed S.; Husain, Syed A.; Raish, Mohammad; Sharma, Deepika R; Kar, Premashis

    2005-01-01

    AIM: (1) To gain information on immune responses to an accelerated schedule of 0, 1, and 2 mo in paramedical staff and BDS students who are at an increased risk of getting hepatitis B infection and come under high risk groups. (2) To assess the efficacy and safety of Enivac-HB in different age groups, using genetically modified yeast strain Pichia pastoris, a new recombinant hepatitis B vaccine developed and manufactured in India.

  18. Dealing with phraseology in business dictionaries: focus on dictionary functions – not phrases

    OpenAIRE

    Leroyer, Patrick

    2006-01-01

    The language of written business communication is characterised by the extensive use of phraseology, not only in terms of collocations and idiomatic expressions, but also of standard phrases in prototypical business genres. In any case, the phraseological information should be included in business dictionaries (in the following referred to as BDs) in accordance with the planned dictionary functions. Hence, the selection and presentation of the phraseological information should be decided by t...

  19. 1,25-Dihydroxyvitamin-D3 Induces Avian β-Defensin Gene Expression in Chickens.

    Directory of Open Access Journals (Sweden)

    Long Zhang

    Full Text Available Host defense peptides (HDPs play a critical role in innate immunity. Specific modulation of endogenous HDP synthesis by dietary compounds has been regarded as a novel approach to boost immunity and disease resistance in animal production. 1,25-dihydroxy vitamin D3 (1,25D3 is well known as a powerful HDP inducer in humans, but limited information about the effect of 1,25D3 on HDPs in poultry is available. Here, we sought to examine whether 1,25D3 could stimulate avian β-defensin (AvBD expression in chickens. We used chicken embryo intestinal epithelial cells (CEIEPCs and peripheral blood mononuclear cells (PBMCs to study the effect of 1,25D3 on the expression of AvBDs. We observed that 1,25D3 is able to up-regulate the expression of several AvBDs in CEIEPCs and PBMCs, whereas it increased the amounts of AvBD4 mRNA in CEIEPCs only in the presence of lipopolysaccharide (LPS. On the other hand, LPS treatment not only inhibited the expression of CYP24A1 but also altered the expression pattern of VDR in CEIEPCs. Furthermore, AvBDs were not directly regulated by 1,25D3, as cycloheximide completely blocked 1,25D3-induced expression of AvBDs. Our observations suggest that 1,25D3 is capable of inducing AvBD gene expression and is a potential antibiotic alternative through augmentation of host innate immunity as well as disease control in chickens.

  20. 1,25-Dihydroxyvitamin-D3 Induces Avian β-Defensin Gene Expression in Chickens

    Science.gov (United States)

    Zhang, Guolong; Ouyang, Linghua; Robinson, Kelsy; Tang, Yanqiang; Zhu, Qing; Li, Diyan; Hu, Yaodong; Liu, Yiping

    2016-01-01

    Host defense peptides (HDPs) play a critical role in innate immunity. Specific modulation of endogenous HDP synthesis by dietary compounds has been regarded as a novel approach to boost immunity and disease resistance in animal production. 1,25-dihydroxy vitamin D3 (1,25D3) is well known as a powerful HDP inducer in humans, but limited information about the effect of 1,25D3 on HDPs in poultry is available. Here, we sought to examine whether 1,25D3 could stimulate avian β-defensin (AvBD) expression in chickens. We used chicken embryo intestinal epithelial cells (CEIEPCs) and peripheral blood mononuclear cells (PBMCs) to study the effect of 1,25D3 on the expression of AvBDs. We observed that 1,25D3 is able to up-regulate the expression of several AvBDs in CEIEPCs and PBMCs, whereas it increased the amounts of AvBD4 mRNA in CEIEPCs only in the presence of lipopolysaccharide (LPS). On the other hand, LPS treatment not only inhibited the expression of CYP24A1 but also altered the expression pattern of VDR in CEIEPCs. Furthermore, AvBDs were not directly regulated by 1,25D3, as cycloheximide completely blocked 1,25D3-induced expression of AvBDs. Our observations suggest that 1,25D3 is capable of inducing AvBD gene expression and is a potential antibiotic alternative through augmentation of host innate immunity as well as disease control in chickens. PMID:27135828

  1. Ability of Gordonia alkanivorans strain 1B for enhanced desulfurization of dibenzothiophene and its derivatives using fructose as carbon source

    OpenAIRE

    Alves, Luís Manuel; Silva, Tiago P.; A. S. Fernandes; Paixão, Susana M.

    2014-01-01

    In order to keep up the strict sulfur limits on fossil fuels and their derivatives, refineries commonly use a desulfurization method, which combines high temperatures and pressures with molecular hydrogen known as hydrodesulfurization (HDS). However, the effectiveness of HDS to desulfurize recalcitrant organic aromatic compounds such as dibenzothiophene (DBT) or its derivatives is low. Biodesulfurization (BDS) has been described as a promising complementary technique to HDS. Using microor...

  2. Overcoming the Challenges of BeiDou Receiver Implementation

    Directory of Open Access Journals (Sweden)

    Mohammad Zahidul H. Bhuiyan

    2014-11-01

    Full Text Available Global Navigation Satellite System (GNSS-based positioning is experiencing rapid changes. The existing GPS and the GLONASS systems are being modernized to better serve the current challenging applications under harsh signal conditions. These modernizations include increasing the number of transmission frequencies and changes to the signal components. In addition, the Chinese BeiDou Navigation Satellite system (BDS and the European Galileo are currently under development for global operation. Therefore, in view of these new upcoming systems the research and development of GNSS receivers has been experiencing a new upsurge. In this article, the authors discuss the main functionalities of a GNSS receiver in view of BDS. While describing the main functionalities of a software-defined BeiDou receiver, the authors also highlight the similarities and differences between the signal characteristics of the BeiDou B1 open service signal and the legacy GPS L1 C/A signal, as in general they both exhibit similar characteristics. In addition, the authors implement a novel acquisition technique for long coherent integration in the presence of NH code modulation in BeiDou D1 signal. Furthermore, a simple phase-preserved coherent integration based acquisition scheme is implemented for BeiDou GEO satellite acquisition. Apart from the above BeiDou-specific implementations, a novel Carrier-to-Noise-density ratio estimation technique is also implemented in the software receiver, which does not necessarily require bit synchronization prior to estimation. Finally, the authors present a BeiDou-only position fix with the implemented software-defined BeiDou receiver considering all three satellite constellations from BDS. In addition, a true multi-GNSS position fix with GPS and BDS systems is also presented while comparing their performances for a static stand-alone code phase-based positioning.

  3. The role of in process qualification in quality improvement of the haemonetics MCS plus leucodepleted platelet concentrate.

    Science.gov (United States)

    Seghatchian, J; Beard, M; Krailadsiri, P

    2000-06-01

    With the implementation of universal leucodepletion in UK all leucodepletion processes have gone through a standard process qualification and quality improvement. The Haemonetics MCS system is a well established automated platelet collection system for the production of double dose leucoreduced platelet concentrate (WBC approximately 70x10(6)/dose). Recently an automated post collection filtration harness system has been introduced (MCS plus LDP) in which platelets are filtered, using an in-line PALL polyester filter (LRFH6 PALL) to reduce the WBC level to below 5x10(6) WBC/dose. This system passed our Phase I evaluation process based on 20-40 runs. However, some changes in the final volume of the products were needed to conform to national guidelines. Large scale trials using the new volume adjusted protocol revealed occasional failure in the leucocyte content. Therefore, 100% testing had to be implemented on all products. A national evaluation was carried out to determine whether changing the filter to a more efficacious one, the LRFXL (PALL) or slowing the filtration flow rate can influence the overall outcome. To reduce donor variability, known donor population were used with identical apheresis conditions. A more consistent and systematic drop in leucocyte content was observed by reducing the flow rate whereas a similar failure (i.e. 1-3%) rate was found both in controls and LRFXL when using the standard head pressure, which is recommended by the manufacturer. A similar failure rate was found using three different low leucocyte counting technologies (Nageotte, flow cytometry and Imagn 2000). It is recommended that a process qualification/validation program should be implemented when even a small modification in the collection system is introduced. PMID:10831919

  4. Multi-wavelength Study of Transition Region Penumbral Subarcsecond Bright Dots Using IRIS and NST

    CERN Document Server

    Deng, Na; Tian, Hui; Kleint, Lucia; Liu, Chang; Xu, Yan; Wang, Haimin

    2016-01-01

    Using high-resolution transition region (TR) observations taken by the Interface Region Imaging Spectrograph (IRIS) mission, Tian et al. (2014b) revealed numerous short-lived subarcsecond bright dots (BDs) above sunspots (mostly located in the penumbrae), which indicate yet unexplained small-scale energy releases. Moreover, whether these subarcsecond TR brightenings have any signature in the lower atmosphere and how they are formed are still not fully resolved. This paper presents a multi-wavelength study of the TR penumbral BDs using a coordinated observation of a near disk-center sunspot with IRIS and the 1.6 m New Solar Telescope (NST) at the Big Bear Solar Observatory. NST provides high-resolution chromospheric and photospheric observations with narrow-band H-alpha imaging spectroscopy and broad-band TiO images, respectively, complementary to IRIS TR observations. A total of 2692 TR penumbral BDs are identified from a 37-minute time series of IRIS 1400 A slitjaw images. Their locations tend to be associat...

  5. Time evolution of ground motion-dependent depolarisation at linear colliders

    CERN Document Server

    Bailey, I; Beckmann, M; Hartin, A; Helebrant, C; Kaefer, D; List, J; Moortgat-Pick, G

    2011-01-01

    Future linear colliders plan to collide polarised beams and the planned physics reach requires knowledge of the state of polarisation as precisely as possible. The polarised beams can undergo depolarisation due to various mechanisms. In order to quantify the uncertainty due to depolarisation, spin tracking simulations in the International Linear Collider (ILC) Beam Delivery System (BDS) and at the Interaction Point (IP) have been performed. Spin tracking in the BDS was achieved using the BMAD subroutine library, and the CAIN program was used to do spin tracking through the beam-beam collision. Assuming initially aligned beamline elements in the BDS, a ground motion model was applied to obtain realistic random misalignments over various time scales. Depolarisation at the level of 0.1% occurs within a day of ground motion at a noisy site. Depolarisation at the IP also exceeds 0.1% for the nominal parameter sets for both the ILC and for the Compact Linear Collider (CLIC). Theoretical work is underway to include ...

  6. The properties of brown dwarfs and low-mass hydrogen-burning stars formed by disc fragmentation

    CERN Document Server

    Stamatellos, Dimitris

    2008-01-01

    We suggest that a high proportion of brown dwarfs are formed by gravitational fragmentation of massive extended discs around Sun-like stars. Such discs should arise frequently, but should be observed infrequently, precisely because they fragment rapidly. By performing an ensemble of radiation-hydrodynamic simulations, we show that such discs fragment within a few thousand years, and produce mainlybrown dwarf (BDs) stars, but also planetary mass (PM) stars and very low-mass hydrogen-burning (HB) stars. Most of the the PM stars and BDs are ejected by mutual interactions. We analyse the statistical properties of these stars, and compare them with observations. After a few hundred thousand years the Sun-like primary is typically left with a close low-mass HB companion, and two much wider companions: a low-mass HB star and a BD star, or a BD-BD binary. There is a BD desert extending out to at least ~100 AU; this is because BDs tend to be formed further out than low-mass HB stars, and then they tend to be scattered...

  7. Long-term evolution of the inclined geosynchronous orbit in Beidou Navigation Satellite System

    Science.gov (United States)

    Tang, Jingshi; Hou, Xiyun; Liu, Lin

    2016-07-01

    China's Beidou Navigation Satellite System (BDS), unlike other navigation satellite systems, uses several inclined geosynchronous orbits (IGSO) to enhance the accuracy of regional or global navigation. In order to maintain a safe space environment in the vicinity of its operational orbit, it is necessary that the decommissioned satellites be well disposed of. Following up the study on the specific BDS IGSO satellites in the previous COSPAR Scientific Assembly, we now extend the study to understand the underlying dynamics and discuss the long-term evolution of such orbits from a more general perspective. In this paper, we first theoretically analyze the problem using simplified models of 1 and 2 degrees of freedoms (1-/2-dof). Then we extensively investigate the numerically propagated orbits for 200 and 1000 years, applying the results from these simplified models and seeking proper explanations for the underlying dynamics. We especially focus on the eccentricity evolution, which is a major concern regarding the collision hazard. We expect to understand the underlying dynamics governing the long-term evolution of BDS IGSO and gain helpful insight into future disposal strategies.

  8. Self assembled hyaluronic acid nanoparticles as a potential carrier for targeting the inflamed intestinal mucosa.

    Science.gov (United States)

    Vafaei, Seyed Yaser; Esmaeili, Motahareh; Amini, Mohsen; Atyabi, Fatemeh; Ostad, Seyed Naser; Dinarvand, Rassoul

    2016-06-25

    To develop a nanoparticulate drug carrier for targeting of the inflamed intestinal mucosa, amphiphilic hyaluronic acid (HA) conjugates were synthesized, which could form self-assembled nanoparticles (NPs) in aqueous solution and budesonide (BDS) was loaded into the HANPs. Their particle sizes were in the range of 177 to 293nm with negative surface charge. The model of inflammatory CACO-2 cells was utilized to investigate the therapeutic potential of budesonide loaded HA nanocarriers. The highest expression of CD44 receptors was found on inflamed Caco-2 cells, as determined by flow cytometry. FITC-labeled HANPs revealed greater uptake in inflamed CACO-2 cells compared to untreated CACO-2 and CD44-negative cell lines, NIH3T3. BDS loaded HANPs displayed almost no toxicity indicating HANPs are excellent biocompatible nano-carriers. BDS loaded HANPs demonstrated higher anti-inflammatory effect on IL-8 and TNF-α secretion in inflamed cell model compared to the same dose of free drug. These results revealed the promising potential of HA nanoparticles as a targeted drug delivery system for IBD treatment. PMID:27083829

  9. Nonthyroidal illness syndrome in patients with subarachnoid hemorrhage due to intracranial aneurysm Sindrome da doença não tiroideana em pacientes com hemorragia subaracnoidea devida a aneurisma cerebral

    Directory of Open Access Journals (Sweden)

    Luiz Augusto Casulari

    2004-03-01

    Full Text Available We have previously reported that subarachnoid hemorrhage due to ruptured intracranial aneurysm (SH is associated with changes in the hormonal profile in the first 24 hours after the event. We proposed that the hormonal changes observed are due to the intense stress to which the patients are exposed. However, the thyroidal hormonal profile is indicative of the presence of a nonthyroidal illness syndrome (NTIS. In this paper, we examined whether the change in the thyroid hormone profile is compatible with a NTIS. Two groups of patients were included in the study: A 30 patients with SH (21 females and 9 males; 41.7±11.4 years and B a control group including 25 patients with benign diseases of the spine (BDS (lumbar disc hernia or stable spinal trauma (8 females and 17 males; 41.3±14.2 years. In a subgroup of eight patients of each group serum triiodothyronine (T3 and reverse T3 levels were measured. The blood samples were obtained between 8:00 and 9:00 AM. The following results were obtained: The SH group had smaller serum T3 and free T4 levels than the BDS group (pNós apresentamos previamente que a hemorragia subaracnoidea devido à ruptura de aneurisma intracraniano (SH está associada com alterações no perfil hormonal nas primeiras 24 horas após o evento. Nós propusemos que as alterações hormonais observadas são devidas ao intenso estresse ao qual os pacientes estão expostos. Contudo, o perfil hormonal tireoidiano é indicativo da presença da síndrome da doença não tireoidiana (NTIS. Neste trabalho, examinamos se as alterações no perfil dos hormônios tireoidianos são compatíveis com a NTIS. Dois grupos de pacientes foram incluídos no estudo: A 30 pacientes com SH (21 mulheres e 9 homens; 41,7±11,4 anos e B um grupo controle incluindo 25 pacientes com doenças benignas da coluna (BDS (hérnia de disco lombar ou estável trauma da coluna (8 mulheres e 17 homens; 41,3±14,2 anos. Em um subgrupo de oito pacientes de cada grupo

  10. Estimating zenith tropospheric delays from BeiDou navigation satellite system observations.

    Science.gov (United States)

    Xu, Aigong; Xu, Zongqiu; Ge, Maorong; Xu, Xinchao; Zhu, Huizhong; Sui, Xin

    2013-01-01

    The GNSS derived Zenith Tropospheric Delay (ZTD) plays today a very critical role in meteorological study and weather forecasts, as ZTDs of thousands of GNSS stations are operationally assimilated into numerical weather prediction models. Recently, the Chinese BeiDou Navigation Satellite System (BDS) was officially announced to provide operational services around China and its neighborhood and it was demonstrated to be very promising for precise navigation and positioning. In this contribution, we concentrate on estimating ZTD using BDS observations to assess its capacity for troposphere remote sensing. A local network which is about 250 km from Beijing and comprised of six stations equipped with GPS- and BDS-capable receivers is utilized. Data from 5 to 8 November 2012 collected on the network is processed in network mode using precise orbits and in Precise Point Positioning mode using precise orbits and clocks. The precise orbits and clocks are generated from a tracking network with most of the stations in China and several stations around the world. The derived ZTDs are compared with that estimated from GPS data using the final products of the International GNSS Service (IGS). The comparison shows that the bias and the standard deviation of the ZTD differences are about 2 mm and 5 mm, respectively, which are very close to the differences of GPS ZTD estimated using different software packages. PMID:23552104

  11. Estimating Zenith Tropospheric Delays from BeiDou Navigation Satellite System Observations

    Directory of Open Access Journals (Sweden)

    Xin Sui

    2013-04-01

    Full Text Available The GNSS derived Zenith Tropospheric Delay (ZTD plays today a very critical role in meteorological study and weather forecasts, as ZTDs of thousands of GNSS stations are operationally assimilated into numerical weather prediction models. Recently, the Chinese BeiDou Navigation Satellite System (BDS was officially announced to provide operational services around China and its neighborhood and it was demonstrated to be very promising for precise navigation and positioning. In this contribution, we concentrate on estimating ZTD using BDS observations to assess its capacity for troposphere remote sensing. A local network which is about 250 km from Beijing and comprised of six stations equipped with GPS- and BDS-capable receivers is utilized. Data from 5 to 8 November 2012 collected on the network is processed in network mode using precise orbits and in Precise Point Positioning mode using precise orbits and clocks. The precise orbits and clocks are generated from a tracking network with most of the stations in China and several stations around the world. The derived ZTDs are compared with that estimated from GPS data using the final products of the International GNSS Service (IGS. The comparison shows that the bias and the standard deviation of the ZTD differences are about 2 mm and 5 mm, respectively, which are very close to the differences of GPS ZTD estimated using different software packages.

  12. New Brown Dwarfs and an Updated Initial Mass Function in Taurus

    CERN Document Server

    Luhman, K L

    2004-01-01

    I have performed a search for young low-mass stars and brown dwarfs (BDs) in 2 regions encompassing a total area of 4 deg^2 in the Taurus star-forming region, discovering 15 new members of Taurus. In addition, I present 7 new members outside of these areas from the initial stage of a survey of all of Taurus. These 22 objects exhibit spectral types of M4.5-M9.25 and masses of 0.3-0.015 M_sun according to the theoretical evolutionary models of Baraffe and Chabrier, 7 of which are likely to be BDs. Emission in H(alpha), He I, Ca II, [O I], and [S II] and excess emission in optical and near-IR bands among some of these objects suggest the presence of accretion, outflows, and circumstellar disks. The results from the 4 deg^2 survey have been combined with previous studies of Taurus to arrive at an IMF for a total area of 12.4 deg^2. As in the previous IMFs for Taurus, the updated IMF peaks at a higher mass (0.8 M_sun) than the mass functions in IC 348 and Orion (0.1-0.2 M_sun). Meanwhile, the deficit of BDs in Tau...

  13. Dealing with phraseology in business dictionaries: focus on dictionary functions – not phrases

    Directory of Open Access Journals (Sweden)

    Leroyer, Patrick

    2006-01-01

    Full Text Available The language of written business communication is characterised by the extensive use of phraseology, not only in terms of collocations and idiomatic expressions, but also of standard phrases in prototypical business genres. In any case, the phraseological information should be included in business dictionaries (in the following referred to as BDs in accordance with the planned dictionary functions. Hence, the selection and presentation of the phraseological information should be decided by the lexicographer on the basis of the user needs alone and not on the recommendations of the phraseological literature about lexicographical practice. In this paper, I will firstly explain why lexicography and phraseology, although closely associated in a large number of studies, are quite different disciplines, and how their shared interest for dictionary practice in general is based on radically different views. I will then discuss the dictionary functions of BDs and focus on a number of concepts featuring extensive phraseological solutions to show and argue that dealing with phraseology in BDs should always keep focus on dictionary functions.

  14. Vergleichende Studien des Pinus-Krummholzes in den japanischen und europäischen Alpen

    OpenAIRE

    Wilmanns, Otti; Bogenrieder, Arno; Nakamura, Yukito

    1985-01-01

    Die Formation des von Nadelhölzern beherrschten Krummholzes ist sowohl in den japanischen als auch in den europäischen Alpen landschaftsprägend entwickelt; die beiden Ausbildungen werden hier vergleichend-autökologisch und vergleichend-pflanzensoziologisch betrachtet. Schlüsselart des (Nadel-) Krummholzes ist in Japan Pinus pumila (Pall.) Regel, in Europa Pinus mugo Turra. P. pumila unterscheidet sich bei an sich gleichem Wuchs durch die Fähigkeit, an älteren Ästen Nebenwurzeln und damit Poly...

  15. Un problema de intertextualidad en poesía helenística

    OpenAIRE

    Montes Cala, José Guillermo

    1995-01-01

    En este artículo el autor ofrece un nuevo análisis comparado de Call. Lav. Pall. 18-23 y Theoc. 18.22-31, dos pasajes de poesía helenística con obvias coincidencias léxicas, con el propósito de discutir los argumentos de Bulloch en favor de que en el Himno 5 Calímaco conscientemente imita a Teócrito para sugerirnos que Atena es de hecho tan bella y exquisita como lo es Helena en el Id. 18.

  16. Fighting the waterborne menace.

    Science.gov (United States)

    Baillie, Jonathan

    2010-03-01

    Although only around 400 cases are reported annually to the U.K.'s Health Protection Agency (HPA), climate change, and thus warmer cold water supplies entering hospitals, the bacterium's apparent ability to mutate, and the considerable challenge of properly monitoring, and successfully identifying and addressing, all potential infection sources on a large hospital estate mean an increasing risk of hospital patients acquiring the potentially deadly waterborne infection, Legionnaires' disease. This was the warning from a top U.K. microbiologist at a recent "waterborne infection masterclass" organised by specialist water filtration product supplier Pall Medical in Antwerp. Jonathan Baillie reports. PMID:20364631

  17. Application of fine absolute rated filters to PWR CVCS and radwaste filter duties

    International Nuclear Information System (INIS)

    Filters for PWR systems have generally been specified in terms of nominal removal ratings. Products supplied by different manufacturers against these specifications vary considerably in removal efficiency and service life. The paper describes the method used by Pall Corporation for reliable, reproducible assessment of filter performance and determination of absolute filtration ratings. The old nominal specifications are shown to be too coarse for effective removal of particle borne activity. The introduction into service of new absolute rated fine filter media with positive zeta potential is described. (author)

  18. Drip Irrigation Conditions within the Scope of Mixed Deposited Salt Resistant to Salt Grass and the Changing Trend of Salt%滴灌条件下积盐范围内混种耐盐草及盐分变化趋势的研究

    Institute of Scientific and Technical Information of China (English)

    穆哈西; 赛尔江·乌尔曼别克

    2011-01-01

    以pH=7.9的水作为灌溉水源,土壤含水率、土壤密度及滴头流量不同的条件下,对土壤湿润体的变化过程进行试验,确定湿润峰及积盐范围,在积盐范围内混种盐角草和猪毛菜。测定土壤酸碱度及易溶盐离子总量的减少量,并积盐范围内混种的盐角草和猪毛菜与普通土壤中栽培的盐角草和猪毛菜的盐含量进行对比。结果表明,盐角草吸走部分Na+、Cl-离子,猪毛菜吸走土壤中的CO32-、SO42-离子,积盐范围内土深20cm处总含盐量降低了0.26g/kg。%pH=7.9 to the water as irrigation water,soil moisture,soil bulk density and drops under the condition of different head flow,moist soil body of the change process,determine the wet peak and deposited salt,salt in product range within the scope of mixed salt grass and Salsola collina pall.Angle Measuring soil ph and soluble salt ions decrease of total amount deposited salt,and within the scope of mixed salt grass and Salsola collina pall.and Angle of the cultivation common soil salt Angle grass and Salsola collina pall the salt content of the dishes were compared.The results show that,salt Angle grass attract part,making Na+ and CI-ions,Salsola collina pall salt inhibit drain on the soil of CO2-3 and SO2-4 ions,deposited salt-within 20 cm deep soil in salt content at reduced total 0.26 g/kg.

  19. Earth observations during Space Shuttle flight STS-26: Discovery's mission to earth - September 29-October 3, 1988

    Science.gov (United States)

    Wood, C. A.; Helfert, M. R.; Lulla, K. P.; Covey, R. O.

    1989-01-01

    During the late September-early October, 1988 flight of the Space Shuttle Discovery, astronauts took 1505 photographs of earth using handheld cameras. The resulting pictures provide an overview, not available from any other source, of dynamic environmental phenomena on five continents. The Discovery photographs show that: (1) atmospheric clarity has improved in the Northern Hemisphere, (2) widespread burning of natural vegetation throughout the Southern Hemisphere continues to generate immense smoke palls and extensive sedimentation in rivers and estuaries, and (3) although the drought in Africa was partially relieved by heavy rains in autumn, 1988, Lakes Chad and Nasser are at the lowest levels ever seen from space.

  20. 铁线莲属威灵仙组修订(续)%A revision of Clematis sect. Clematis (Ranunculaceae) (Continued)

    Institute of Scientific and Technical Information of China (English)

    王文采

    2003-01-01

    @@ Subsection 4. Angustifoliae Tamura in Sci. Rep. Osaka Univ. 4: 55. 1955 et 16 (2): 33. 1967; M. C. Chang in Fl. Reip. Pop. Sin. 28: 156. 1980. --Sect. Flammula DC. Subsect. Angustifoliae (Tamura) Tamura in Acta Phytotax. Geobot. 16: 81. 1956 et 38: 43. 1987; M. Johnson, Klematis 603. 1997; Grey_Wils., Clematis 113. 2000. -- Sect. Angustifoliae (Tamura) Serov in Bot. Zhurn. 73 (12): 1740. 1988; Tamura in Heipko, Engler's Nat. Pflanzenfam., ed. 2, 17a (4): 383. 1995. Type: C. Hexapetala Pall.

  1. 威灵仙临床新用

    Institute of Scientific and Technical Information of China (English)

    胡烈

    2001-01-01

    @@ 威灵仙为毛茛科植物威灵仙Clematis Chinensis Osbeck.棉团铁线莲C. herapetala pall.东北铁线莲C.等的根及根茎.又名:铁脚威灵仙、灵仙、黑脚威灵仙.喜生于山坡、沟边、路旁草丛中.主产于江苏、安徽、浙江等地.秋季采挖,去净茎叶,冼净泥土,晒干,或切成段晒于.生用或酒炒后用.

  2. О НОВЫХ И НАИБОЛЕЕ РЕДКИХ ВИДАХ ТАМБОВСКОЙФЛОРЫ. СООБЩЕНИЕ 4

    OpenAIRE

    Соколов, Александр; Соколова, Людмила

    2014-01-01

    В работе сообщаются сведения о новых (Astragalus pubiflorus (Pall.)) DC., Veronica persica Poir., Dipsacus strigosus Willd. ex Roem. et Schult.) и наиболее редких (Ephedra distachya L., Stipa lessingiana Trin. et Rupr., S. pulcherrima C. Koch, Rhynchospora alba (L.) Vahl, Carex humilis Leysser, Veratrum nigrum L., Anthericum ramosum L., Lilium martagon L., Ceratocarpus arenarius L., Arenaria procera Spreng., Silene sibirica (L.) Pers., Actaea spicata L., Aconitum anthora L., Clematis integrif...

  3. Aerobic desulfurization of biogas by acidic biotrickling filtration in a randomly packed reactor

    OpenAIRE

    Montebello, Andrea M.; Mora Garrido, Mabel; López de León, Luís Rafael; Bezerra, Tercia; Gamisans Noguera, Javier; Lafuente Sancho, Francisco Javier; Baeza Labat, Mireia; Gabriel Buguña, David

    2014-01-01

    Biotrickling filters for biogas desulfurization still must prove their stability and robustness in the long run under extreme conditions. Long-term desulfurization of high loads of H2S under acidic pH was studied in a lab-scale aerobic biotrickling filter packed with metallic Pall rings. Reference operating conditions at steady-state corresponded to an empty bed residence time (EBRT) of 130s, H2S loading rate of 52gS-H2Sm-3h-1 and pH 2.50-2.75. The EBRT reduction showed that the critical EBRT...

  4. Surface selective membranes for carbon dioxide separation

    Energy Technology Data Exchange (ETDEWEB)

    Luebke, D.R.; Pennline, H.W.; Myers, C.R.

    2005-09-01

    In this study, hybrid membranes have been developed for the selective separation of CO2 from mixtures containing H2. Beginning with commercially available Pall alumina membrane tubes with nominal pore diameter of 5 nm, hybrids were produced by silation with a variety of functionalities designed to facilitate the selective adsorption of CO2 onto the pore surface. The goal is to produce a membrane which can harness the power of surface diffusion to give the selectivity of polymer membranes with the permeance of inorganic membranes.

  5. Are female daycare workers at greater risk of cytomegalovirus infection? A secondary data analysis of CMV seroprevalence between 2010 and 2013 in Hamburg, Germany

    Directory of Open Access Journals (Sweden)

    Stranzinger, Johanna

    2016-04-01

    Full Text Available Background: Close contact with asymptomatic children younger than three years is a risk factor for a primary cytomegalovirus (CMV infection. In pregnant women, such primary infection increases the risk of CMV-induced feto- or embryopathy. Daycare providers have therefore implemented working restrictions for pregnant daycare workers (DCWs in accordance with legislation and guidelines for maternity protection. However, little is known about the infection risk for DCWs. We therefore compared the prevalence of CMV antibodies of pregnant DCWs to that of female blood donors (BDs.Method: In a secondary data analysis, the prevalence of anti-CMV IgG among pregnant DCWs (N=509 in daycare centers (DCCs was compared to the prevalence of female first-time BDs (N=14,358 from the greater region of Hamburg, Germany. Data collection took place between 2010 and 2013. The influence of other risk factors such as age, pregnancies and place of residence was evaluated using logistic regression models. Results: The prevalence of CMV antibodies in pregnant DCWs was higher than in female BDs (54.6 vs 41.5%; OR 1.6; 95%CI 1.3–1.9. The subgroup of BDs who had given birth to at least one child and who lived in the city of Hamburg (N=2,591 had a prevalence of CMV antibodies similar to the prevalence in pregnant DCWs (53.9 vs 54.6%; OR 0.9; 95%CI 0.8–1.2. Age, pregnancy history and living in the center of Hamburg were risk factors for CMV infections.Conclusion: The comparison of pregnant DCWs to the best-matching subgroup of female first-time BDs with past pregnancies and living in the city of Hamburg does not indicate an elevated risk of CMV infection among DCWs. However, as two secondary data sets from convenience samples were used, a more detailed investigation of the risk factors other than place of residence, age and maternity was not possible. Therefore, the CMV infection risk in DCWs should be further studied by taking into consideration the potential preventive

  6. Are female daycare workers at greater risk of cytomegalovirus infection? A secondary data analysis of CMV seroprevalence between 2010 and 2013 in Hamburg, Germany

    Science.gov (United States)

    Stranzinger, Johanna; Kozak, Agnessa; Schilgen, Benjamin; Paris, Diana; Nießen, Thomas; Schmidt, Lutz; Wille, Andreas; Wagner, Norbert L.; Nienhaus, Albert

    2016-01-01

    Background: Close contact with asymptomatic children younger than three years is a risk factor for a primary cytomegalovirus (CMV) infection. In pregnant women, such primary infection increases the risk of CMV-induced feto- or embryopathy. Daycare providers have therefore implemented working restrictions for pregnant daycare workers (DCWs) in accordance with legislation and guidelines for maternity protection. However, little is known about the infection risk for DCWs. We therefore compared the prevalence of CMV antibodies of pregnant DCWs to that of female blood donors (BDs). Method: In a secondary data analysis, the prevalence of anti-CMV IgG among pregnant DCWs (N=509) in daycare centers (DCCs) was compared to the prevalence of female first-time BDs (N=14,358) from the greater region of Hamburg, Germany. Data collection took place between 2010 and 2013. The influence of other risk factors such as age, pregnancies and place of residence was evaluated using logistic regression models. Results: The prevalence of CMV antibodies in pregnant DCWs was higher than in female BDs (54.6 vs 41.5%; OR 1.6; 95%CI 1.3–1.9). The subgroup of BDs who had given birth to at least one child and who lived in the city of Hamburg (N=2,591) had a prevalence of CMV antibodies similar to the prevalence in pregnant DCWs (53.9 vs 54.6%; OR 0.9; 95%CI 0.8–1.2). Age, pregnancy history and living in the center of Hamburg were risk factors for CMV infections. Conclusion: The comparison of pregnant DCWs to the best-matching subgroup of female first-time BDs with past pregnancies and living in the city of Hamburg does not indicate an elevated risk of CMV infection among DCWs. However, as two secondary data sets from convenience samples were used, a more detailed investigation of the risk factors other than place of residence, age and maternity was not possible. Therefore, the CMV infection risk in DCWs should be further studied by taking into consideration the potential preventive effect of

  7. Induction and Proliferation Conditions of Onion(Allium cepa L.) Embryogenic Callus%洋葱胚性愈伤组织的诱导及增殖条件的研究

    Institute of Scientific and Technical Information of China (English)

    代月; 吴雄; 朴炫春; 霍雨猛; 缪军; 廉美兰

    2012-01-01

    [目的]探讨洋葱离体培养的最佳条件,为建立其高频再生体系及转基因研究奠定技术基础.[方法]以洋葱(Allium cepa L.)种子为外植体,对洋葱愈伤组织的诱导、胚性愈伤组织获得及增殖的培养条件进行了初步研究.[结果]不同培养基种类对愈伤组织的诱导有影响,BDS优于MS和B5培养基;当培养基中2,4-D浓度为0.5 mg,/L时种子出愈率最高;适当降低生长素浓度,添加分裂素BA能够促进胚性愈伤组织的发生,且无分化现象产生,胚性愈伤组织诱导最佳培养基为BDS+2,4-D 0.25 mg/L+BA 2.0 mg/L,增殖最佳培养基为BDS+2,4-D O.25 mg/L+BA 1.0 mg/L.[结论]该试验建立的基因转化受体系统为洋葱基因转化奠定了良好基础.%[Objective] To explore the best conditions for the in vitro culture of onion, so as to lay technical foundation for its trangenic research and the establishment of high frequency regeneration system. [ Method] With the onion seeds as explants, the induction and proliferation conditions of onion (Alliiim r.epa L. ) callus and embryogenic callus were preliminarily studied. [ Result] The types of callus produced certain impact on the induction of callus, BDS was better than MS and B5; the callus rate was the highest at the concentrations of 0. 5 mg/L 2,4-D; the appropriate reduction of auxin concentration and addition of cytokinin BA could promote the induction of enbryogenic callus without differentiation, the best embryogenic callus induction medium was BDS +2,4-D 0. 25 mg/L + BA 2.0 mg/L and the best proliferation medium was BDS + 2,4-D 0.25 mg/L + BA 1.0 mg/L. [Conclusion] Hie transgenic receptor system established in this experiment lays good foundation for the genetic transformation of onion.

  8. BANYAN. VII. A New Population of Young Substellar Candidate Members of Nearby Moving Groups from the BASS Survey

    Science.gov (United States)

    Gagné, Jonathan; Faherty, Jacqueline K.; Cruz, Kelle L.; Lafreniére, David; Doyon, René; Malo, Lison; Burgasser, Adam J.; Naud, Marie-Eve; Artigau, Étienne; Bouchard, Sandie; Gizis, John E.; Albert, Loïc

    2015-08-01

    We present the results of a near-infrared (NIR) spectroscopic follow-up survey of 182 M4-L7 low-mass stars and brown dwarfs (BDs) from the BANYAN All-Sky Survey (BASS) for candidate members of nearby, young moving groups (YMGs). We confirm signs of low gravity for 42 new BD discoveries with estimated masses between 8 and 75 {M}{Jup} and identify previously unrecognized signs of low gravity for 24 known BDs. We refine the fraction of low-gravity dwarfs in the high-probability BASS sample to ˜82%. We use this unique sample of 66 young BDs, supplemented with 22 young BDs from the literature, to construct new empirical NIR absolute magnitude and color sequences for low-gravity BDs. We show that low-resolution NIR spectroscopy alone cannot differentiate between the ages of YMGs younger than ˜120 Myr, and that the BT-Settl atmosphere models do not reproduce well the dust clouds in field or low-gravity L-type dwarfs. We obtain a spectroscopic confirmation of low gravity for 2MASS J14252798-3650229, which is a new ˜27 {M}{Jup}, L4 γ bona fide member of AB Doradus. We identify a total of 19 new low-gravity candidate members of YMGs with estimated masses below 13 {M}{Jup}, 7 of which have kinematically estimated distances within 40 pc. These objects will be valuable benchmarks for a detailed atmospheric characterization of planetary-mass objects with the next generation of instruments. We find 16 strong candidate members of the Tucana-Horologium association with estimated masses between 12.5 and 14 {M}{Jup}, a regime where our study was particularly sensitive. This would indicate that for this association there is at least one isolated object in this mass range for every {17.5}-5.0+6.6 main-sequence stellar member, a number significantly higher than expected based on standard log-normal initial mass function, however, in the absence of radial velocity and parallax measurements for all of them, it is likely that this over-density is caused by a number of young interlopers

  9. PROTOPLANETARY DISK MASSES FROM STARS TO BROWN DWARFS

    Energy Technology Data Exchange (ETDEWEB)

    Mohanty, Subhanjoy; Mortlock, Daniel [Imperial College London, 1010 Blackett Lab, Prince Consort Rd., London SW7 2AZ (United Kingdom); Greaves, Jane [SUPA, Physics and Astronomy, University of St. Andrews, North Haugh, St. Andrews, Fife KY16 9SS (United Kingdom); Pascucci, Ilaria; Apai, Daniel [Department of Planetary Sciences and Lunar and Planetary Laboratory, University of Arizona, Tucson AZ 85721 (United States); Scholz, Aleks [School of Cosmic Physics, Dublin Institute for Advanced Studies, 31 Fitzwilliam Place, Dublin 2 (Ireland); Thompson, Mark [Centre for Astrophysics Research, University of Hertfordshire, College Lane, Hatfield AL10 9AB (United Kingdom); Lodato, Giuseppe [Dipartimento di Fisica, Universita Degli Studi di Milano, Via Celoria 16, I-20133 Milano (Italy); Looper, Dagny, E-mail: s.mohanty@imperial.ac.uk [Institute for Astronomy, University of Hawaii, 2680 Woodlawn Dr., Honolulu, HI 96822 (United States)

    2013-08-20

    We present SCUBA-2 850 {mu}m observations of seven very low mass stars (VLMS) and brown dwarfs (BDs). Three are in Taurus and four in the TW Hydrae Association (TWA), and all are classical T Tauri (cTT) analogs. We detect two of the three Taurus disks (one only marginally), but none of the TWA ones. For standard grains in cTT disks, our 3{sigma} limits correspond to a dust mass of 1.2 M{sub Circled-Plus} in Taurus and a mere 0.2 M{sub Circled-Plus} in the TWA (3-10 Multiplication-Sign deeper than previous work). We combine our data with other submillimeter/millimeter (sub-mm/mm) surveys of Taurus, {rho} Oph, and the TWA to investigate the trends in disk mass and grain growth during the cTT phase. Assuming a gas-to-dust mass ratio of 100:1 and fiducial surface density and temperature profiles guided by current data, we find the following. (1) The minimum disk outer radius required to explain the upper envelope of sub-mm/mm fluxes is {approx}100 AU for intermediate-mass stars, solar types, and VLMS, and {approx}20 AU for BDs. (2) While the upper envelope of apparent disk masses increases with M{sub *} from BDs to VLMS to solar-type stars, no such increase is observed from solar-type to intermediate-mass stars. We propose this is due to enhanced photoevaporation around intermediate stellar masses. (3) Many of the disks around Taurus and {rho} Oph intermediate-mass and solar-type stars evince an opacity index of {beta} {approx} 0-1, indicating significant grain growth. Of the only four VLMS/BDs in these regions with multi-wavelength measurements, three are consistent with considerable grain growth, though optically thick disks are not ruled out. (4) For the TWA VLMS (TWA 30A and B), combining our 850 {mu}m fluxes with the known accretion rates and ages suggests substantial grain growth by 10 Myr, comparable to that in the previously studied TWA cTTs Hen 3-600A and TW Hya. The degree of grain growth in the TWA BDs (2M1207A and SSPM1102) remains largely unknown. (5) A

  10. Specificity of germination of heteromorphic seeds in four annuals (Salsola L.) at different temperatures in the Junggar basin

    International Nuclear Information System (INIS)

    Salsola L. is a large genus of arid desert plants that are primarily distributed in the Junggar Basin, China. We analysed their ability to adapt to arid habitats by comparing differences in germination characteristics of the species and populations of Salsola affinis C. A. Mey, Salsola korshinskyi Drob., Salsola brachiata Pall. and Salsola nitraria Pall. We classified the 4 species into four types (A, B, C and D) according to seed wing and seed size, and the heteromorphic seeds were incubatedunder different temperature regimes (0/10 degree C, 5/15 degree C, 10/25 degree C and 20/35 degree C). The 4 species had the highest germination rates and germination potential at 0/1 C. Germination rates and potential decreased with increasing temperature. However, the change range of the germination rate among the four species was different. Type A and B seeds of S. affinis, S. nitraria and S. korshinskyi were dominant at all temperatures and decreased with increasing temperature. The germination rate of type C seeds was between that of type A, B and D seeds. D-type seeds had the lowest germination rate and the lowest germination potential under the four temperature regimes among the four species but the differences were not significant. The germination rates of the four types of S. brachiata seeds did not significantly change with temperature. These results suggest that Salsola spp. can germinate continuously from spring to autumn to adapt to moisture fluctuations in the desert. (author)

  11. Evaluation Of Alternative Filter Media For The Rotary Microfilter, Phase 2

    International Nuclear Information System (INIS)

    Testing was conducted at the Savannah River National Laboratory (SRNL) to investigate filter membrane performance in an effort to increase rotary microfilter (RMF) throughput. Membranes were tested in the SpinTek Filtration, Inc. Static Test Cell (STC), which permitted quick and easy testing of several different membranes. Testing consisted of 100 hours tests with two different slurry feeds, based on recommendations from the phase 1 testing. One feed contained Monosodium Titanate (MST) solids in a simulated salt solution. The other feed contained simulated sludge batch 6 (SB6) solids in a simulated salt solution. Five membranes were tested, one each from filter manufactures Pall and Porvair and three from the Oak Ridge National Laboratory (ORNL). The membrane from Pall is the current membrane used on the latest generation RMF. The Porvair membrane performed well in previous STC tests as well as one of the ORNL membranes. The other two membranes from ORNL were recently developed and not available for the previous STC test. The results indicate that the Porvair filter performed best with the MST slurry and the ORNL SVB6-1B filter performed best with the SB6 slurry. Difficulty was encountered with the ORNL filters due to their dimensional thickness, which was greater than the recommended filter thickness for the STC. The STC equipment was modified to complete the testing of the ORNL filters.

  12. Pyrolysis Oil Stabilization: Hot-Gas Filtration; Cooperative Research and Development Final Report, CRADA Number CRD-09-333

    Energy Technology Data Exchange (ETDEWEB)

    Baldwin, R.

    2012-07-01

    The hypothesis that was tested in this task was that separation of char, with its associated mineral matter from pyrolysis vapors before condensation, will lead to improved oil quality and stability with respect to storage and transportation. The metric used to evaluate stability in this case was a 10-fold reduction in the rate of increase of viscosity as determined by ASTM D445 (the accelerated aging test). The primary unit operation that was investigated for this purpose was hot-gas filtration. A custom-built heated candle filter system was fabricated by the Pall Corporation and furnished to NREL for this test campaign. This system consisted of a candle filter element in a containment vessel surrounded by heating elements on the external surface of the vessel. The filter element and housing were interfaced to NREL?s existing 0.5 MTD pyrolysis Process Development Unit (PDU). For these tests the pyrolysis reactor of the PDU was operated in the entrained-flow mode. The HGF test stand was installed on a slipstream from the PDU so that both hot-gas filtered oil and bio-oil that was not hot-gas filtered could be collected for purposes of comparison. Two filter elements from Pall were tested: (1) porous stainless steel (PSS) sintered metal powder; (2) sintered ceramic powder. An extremely sophisticated bio-oil condensation and collection system was designed and fabricated at NREL and interfaced to the filter unit.

  13. Operational aspects, pH transition and microbial shifts of a H2S desulfurizing biotrickling filter with random packing material.

    Science.gov (United States)

    Montebello, Andrea M; Bezerra, Tercia; Rovira, Roger; Rago, Laura; Lafuente, Javier; Gamisans, Xavier; Campoy, Susana; Baeza, Mireia; Gabriel, David

    2013-11-01

    Pall rings, a common random packing material, were used in the biotrickling filtration of biogas with high H2S. Assessment of 600d of operation covered the reactor start-up, the operation at neutral pH and the transition from neutral to acid pH. During the start-up period, operational parameters such as the aeration rate and the trickling liquid velocity were optimized. During the steady-state operation at neutral pH, the performance of the random packing material was investigated by reducing the gas contact time at both constant and increasing H2S loads. The random packing material showed similar elimination capacities and removal efficiencies in comparison with previous studies with a structured packing material, indicating that Pall rings are suitable for biogas desulfurization in biotrickling filters. The diversity of Eubacteria and the structure of the community were investigated before and after the pH transition using the bacterial tag-encoded FLX amplicon pyrosequencing. The pH transition to acid pH drastically reduced the microbial diversity and produced a progressive specialization of the sulfur-oxidizing bacteria community without any detrimental effect on the overall desulfurizing capacity of the reactor. During acidic pH operation, a persistent accumulation of elemental sulfur was found. PMID:24041568

  14. Response to the comment on: “Soon, W., and Legates, D.R., solar irradiance modulation of equator-to-pole (Arctic) temperature gradients: empirical evidence for climate variation on multi-decadal timescales. Journal of Atmospheric and solar-terrestrial physics, 93, (2013) 45-56” by F. Meunier and A. H. Reis

    Science.gov (United States)

    Soon, Willie; Legates, David R.

    2015-06-01

    We thank Meunier and Reis (hereafter as MR) for their comments on our paper. We, however, do not see the relevance of their alternative interpretation to our original results and believe this reflects their confusion regarding our conclusions rather than a discussion on physical mechanisms. In the context of this quote, note that even Pallé et al. (2009:3)admitted that “while the deseasonalized CERES data has a small year to year variability (Fig. 2 of Pallé et al., 2009), the Earthshine data seem to present overly large interannual anomalies, along with a large size of the error bars associated to the yearly means [which] is mostly due to sampling issues, as Earthshine measurements are taken from a single station.”To put this in a different way, the relatively short duration of Earthshine or satellite-borne measurements of global albedo is unable to provide the necessary information on how this important quantity may vary on multi-decadal timescales as studies by Soon and Legates (2013). We note that efforts to 'reconstruct' Earth albedo over a 120-to-130 year period have been discussed by Zavalishin (2014) but we stress that such research requires non-independent information regarding surface temperatures and some unproven assumptions about the thermal inertia of the hydrosphere.

  15. Antimicrobial and antiradical activity of extracts obtained from leaves of three species of the genus pyrus.

    Science.gov (United States)

    Zbigniew, Sroka; Beata, Żbikowska; Kamil, Janicki; Roman, Franiczek; Barbara, Krzyżanowska; Andrzej, Dryś

    2014-08-01

    In this study, extracts were obtained from leaves of Pyrus communis L., Pyrus elaeagrifolia Pall., and Pyrus pyrifolia (Bum.) Nak. These extracts were tested for antiradical and antibacterial activity, as well as for the amount of total phenolic compounds, hydroquinone and arbutin. The antiradical activity was measured using 2,2-diphenyl-1-picrylhydrazyl radical and antibacterial activity with the disk diffusion method. The amount of phenolic compounds was determined using Folin Ciocalteu's phenol reagent, but the amount of hydroquinone and arbutin was measured with high performance liquid chromatography. The strongest antiradical activity was observed for ethyl acetate extract from leaves of P. communis L., and the lowest for the poorly soluble fraction (precipitate) from leaves of P. elaeagrifolia Pall. The highest number of antiradical units per gram of raw materials was noted for leaves of P. communis. The strongest antibacterial activity was measured for ethyl acetate extracts. The calculation of Spearman rank correlation coefficients indicated the existence of a positive correlation between contents of hydroquinone in extracts and their antibacterial activity for almost all investigated bacterial strains. The strains of fungi such as Candida albicans and Saccharomyces cerevisiae were completely resistant to the action of extracts. PMID:24621262

  16. Indication of environmental pollution by means of INAA of the hair of some free living mammals

    International Nuclear Information System (INIS)

    Hair samples collected from free living mammals common hare (Lepus europaeus Pall.), common vole (Microtus arvallis Pall.) and wood mouse (Apodemus sylvaticus L.) have been subjected to instrumental neutron activation analysis (NAA). 18 elements (As,Au,Br,Ce,Co,Cr,Cu,Fe,Hg,K,La,Na,Sb,Sc,Se,Sm,Th,Zn) have been determined in each hair sample. Animal hair samples from areas polluted by thermal power plants burning coal, were taken and compared with hair samples from the animals living in relatively non-polluted control areas. The results show that animal hair samples from areas with higher level of pollution contain usually higher concentrations of toxic and essential elements such as As, Co, Cr, Fe and Se. Muride rodents can be used for more detailed monitoring of environmental exposure than hare. Moreover, hair of common vole shows usually higher levels of contamination as compared with wood mouse, which could be explained by different compositions of feed. Animal hair has been shown to be a rather sensitive indicator of environmental exposure and INAA has proved to be a suitable analytical tool for this purpose. (author)

  17. Improving radwaste processing efficiency at Peach Bottom

    International Nuclear Information System (INIS)

    Two 1100MWe BWRs are located at the Peach Bottom site. These units share a liquid radwaste processing system that consists of precoated filters followed by deep bed demineralizers. Radwaste is segregated and treated in two separate systems; one for floor drain wastes and one for equipment drain wastes (waste collector). The filters are of the precoat type, and were originally outfitted with wedgewire elements. The Pall Rigimesh Septa installed last year at Peach Bottom are constructed of a sintered stainless steel, computer-optimized, multi-layer wire mesh composite. Pall starts with a very fine woven wire mesh and adds non-flow-restricting drainage layers and sinters in a high temperature vacuum furnace which bonds all wires at their points of contact. The result is an extremely strong septum with a fixed pore structure of uniform shape and distribution. The pore structure is fixed and unchanging, even in the face of increasing forward flow differential pressure or in backwash. The new elements at Peach Bottom were direct replacements; no hardware modifications were necessary. The Rigimesh Septa have now been in service since November 1990 without any element failure or resin leakage. Eliminating the need to replace damaged septa and to dispose of and purchase resin is expected to save Philadelphia Electric $90 000 in the first year alone. Additional savings that have not been quantified include the maintenance costs associated with element changeout, and the associated reduction in radiation exposure. (author)

  18. A Sativex®-like combination of phytocannabinoids as a disease-modifying therapy in a viral model of multiple sclerosis

    Science.gov (United States)

    Feliú, A; Moreno-Martet, M; Mecha, M; Carrillo-Salinas, F J; de Lago, E; Fernández-Ruiz, J; Guaza, C

    2015-01-01

    Background and Purpose Sativex® is an oromucosal spray, containing equivalent amounts of Δ9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD)-botanical drug substance (BDS), which has been approved for the treatment of spasticity and pain associated to multiple sclerosis (MS). In this study, we investigated whether Sativex may also serve as a disease-modifying agent in the Theiler's murine encephalomyelitis virus-induced demyelinating disease model of MS. Experimental Approach A Sativex-like combination of phytocannabinoids and each phytocannabinoid alone were administered to mice once they had established MS-like symptoms. Motor activity and the putative targets of these cannabinoids were assessed to evaluate therapeutic efficacy. The accumulation of chondroitin sulfate proteoglycans (CSPGs) and astrogliosis were assessed in the spinal cord and the effect of Sativex on CSPGs production was evaluated in astrocyte cultures. Key Results Sativex improved motor activity – reduced CNS infiltrates, microglial activity, axonal damage – and restored myelin morphology. Similarly, we found weaker vascular cell adhesion molecule-1 staining and IL-1β gene expression but an up-regulation of arginase-1. The astrogliosis and accumulation of CSPGs in the spinal cord in vehicle-infected animals were decreased by Sativex, as was the synthesis and release of CSPGs by astrocytes in culture. We found that CBD-BDS alone alleviated motor deterioration to a similar extent as Sativex, acting through PPARγ receptors whereas Δ9-THC-BDS produced weaker effects, acting through CB2 and primarily CB1 receptors. Conclusions and Implications The data support the therapeutic potential of Sativex to slow MS progression and its relevance in CNS repair. PMID:25857324

  19. Correlation Between Birth Defects and Dietary Nutrition Status in a High Incidence Area of China1

    Institute of Scientific and Technical Information of China (English)

    BAO-YUAN ZHANG; QING-SHAN ZHANG; JIN ZHAO; YU-FU QIN; XIU-FENG YANG; GONG CHEN; JU-FEN LIU; XIN-MING SONG; XIAO-YING ZHENG; TING ZHANG; LIANG-MING LIN; FANG WANG; RUO-LEI XIN; XUE GU; YU-NA HE; DONG-MEI YU; PEI-ZHEN LI

    2008-01-01

    Objective To investigate the association between birth defects and dietary nutrient intake in a high risk area of China.Methods A dietary survey was performed and serum folic acid was measured in women whose pregnancy was affected by neural tube defects(NTDs)or unaffected by any birth defects(BDs)in Zhongyang and Jiaokou Counties in Shanxi Province of China.Results The local average censureption of foods including dark green vegetables,fluits,fat and meat,and nutrient intake(e.g.energy,protein,retinol,riboflavin,vitamin E,and selenium)were lower than the national average level.In women of childbearing age,these regions,the intake of nutrients was much lower than the recommended nutrient intake(9%-77%)The case-centrel dietary nutrition smdv of women whose pregnancy was affected bv BDs(including MTDs and congenital heart defects)demonstrated that,in early pregnancy,adequate nutrition(I.e.eating meat,fresh vegetables,fruit more than once a week)was a protective factor,while eating germinated potatoes was a risk factor.The geometrical mean(p5-p95)of serum folic acid in women with NTD birth defects was 9.6 nmol/L(3.6,23.03),which was significantly lower than that in normal women(14.03 nmol/L). Conclusion Wemen of childbearing age in the two counties of Shanxi Province,Chim,have a marked insufficient intake of some nutrients,especially folic acid,zinc,vitamins A and B12.This nutrient deficiency may be an important risk factor for the high prevalence of birth defects in these regions.Therefore,adequate dietary nutrition in early pregnancy can prevent BDs.

  20. SU-E-T-570: Management of Radiation Oncology Patients with Cochlear Implant and Other Bionic Devices in the Brain and Head and Neck Regions

    Energy Technology Data Exchange (ETDEWEB)

    Guo, F.Q; Chen, Z; Nath, R [Yale New Haven Hospital, New Haven, CT (United States); Yale UniversitySchool of Medicine, New Haven, CT (United States)

    2014-06-01

    Purpose: To investigate the current status of clinical usage of cochlear implant (CI) and other bionic devices (BD) in the brain and head and neck regions (BH and N) and their management in patients during radiotherapy to ensure patient health and safety as well as optimum radiation delivery. Methods: Literature review was performed with both CIs and radiotherapy and their variants as keywords in PubMed, INSPEC and other sources. The focus was on CIs during radiotherapy, but it also included other BDs in BHȦN, such as auditory brainstem implant, bionic retinal implant, and hearing aids, among others. Results: Interactions between CIs and radiation may cause CIs malfunction. The presence of CIs may also cause suboptimum dose distribution if a treatment plan was not well designed. A few studies were performed for the hearing functions of CIs under irradiations of 4 MV and 6 MV x-rays. However, x-rays with higher energies (10 to 18 MV) broadly used in radiotherapy have not been explored. These higher energetic beams are more damaging to electronics due to strong penetrating power and also due to neutrons generated in the treatment process. Modern CIs are designed with more and more complicated integrated circuits, which may be more susceptible to radiation damage and malfunction. Therefore, careful management is important for safety and treatment outcomes. Conclusion: Although AAPM TG-34, TG-63, and TG-203 (update of TG-34, not published yet) reports may be referenced for management of CIs and other BDs in the brain and H and N regions, a site- and device-specified guideline should be developed for CIs and other BDs. Additional evaluation of CI functions under clinically relevant set-ups should also be performed to provide clinicians with better knowledge in clinical decision making.

  1. SU-E-T-570: Management of Radiation Oncology Patients with Cochlear Implant and Other Bionic Devices in the Brain and Head and Neck Regions

    International Nuclear Information System (INIS)

    Purpose: To investigate the current status of clinical usage of cochlear implant (CI) and other bionic devices (BD) in the brain and head and neck regions (BH and N) and their management in patients during radiotherapy to ensure patient health and safety as well as optimum radiation delivery. Methods: Literature review was performed with both CIs and radiotherapy and their variants as keywords in PubMed, INSPEC and other sources. The focus was on CIs during radiotherapy, but it also included other BDs in BHȦN, such as auditory brainstem implant, bionic retinal implant, and hearing aids, among others. Results: Interactions between CIs and radiation may cause CIs malfunction. The presence of CIs may also cause suboptimum dose distribution if a treatment plan was not well designed. A few studies were performed for the hearing functions of CIs under irradiations of 4 MV and 6 MV x-rays. However, x-rays with higher energies (10 to 18 MV) broadly used in radiotherapy have not been explored. These higher energetic beams are more damaging to electronics due to strong penetrating power and also due to neutrons generated in the treatment process. Modern CIs are designed with more and more complicated integrated circuits, which may be more susceptible to radiation damage and malfunction. Therefore, careful management is important for safety and treatment outcomes. Conclusion: Although AAPM TG-34, TG-63, and TG-203 (update of TG-34, not published yet) reports may be referenced for management of CIs and other BDs in the brain and H and N regions, a site- and device-specified guideline should be developed for CIs and other BDs. Additional evaluation of CI functions under clinically relevant set-ups should also be performed to provide clinicians with better knowledge in clinical decision making

  2. Energy storage properties in Ba{sub 0.4}Sr{sub 0.6}TiO{sub 3} ceramics with addition of semi-conductive BaO–B{sub 2}O{sub 3}–SiO{sub 2}–Na{sub 2}CO{sub 3}–K{sub 2}CO{sub 3} glass

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Tong; Jin, Li, E-mail: ljin@mail.xjtu.edu.cn; Shu, Longlong; Hu, Qingyuan; Wei, Xiaoyong, E-mail: wdy@mail.xjtu.edu.cn

    2014-12-25

    Highlights: • Semiconductive BaO–B{sub 2}O{sub 3}–SiO{sub 2}–Na{sub 2}CO{sub 3}–K{sub 2}CO{sub 3} glass was added to Ba{sub 0.4}Sr{sub 0.6}TiO{sub 3} ceramic. • Sintering temperature was lowered about 150 °C with a high relative density (∼98%). • Dielectric constant of BST glass ceramics decrease with increasing Na{sub 2}CO{sub 3} content. • BDS and energy density of BST glass ceramics increase with increasing Na{sub 2}CO{sub 3} content. - Abstract: Semi-conductive BaO–B{sub 2}O{sub 3}–SiO{sub 2}–Na{sub 2}CO{sub 3}–K{sub 2}CO{sub 3} glass additives were added to Ba{sub 0.4}Sr{sub 0.6}TiO{sub 3} (BST) ceramics to investigate its influences on the microstructure, dielectric properties, breakdown strength (BDS), and energy storage density. The sintering temperatures were lowered about 150 °C with a high relative density (∼98%). X-ray diffraction patterns of all BST glass ceramics suggest perovskite structures without any detectable secondary phase. Room temperature dielectric constant of BST glass ceramics decreases with increasing Na{sub 2}CO{sub 3} content. BDS and energy storage density of BST glass ceramics increase with increasing Na{sub 2}CO{sub 3} content, and reach their maxima of 280 kV/cm and 0.72 J/cm{sup 3} at the highest Na{sup +} and K{sup +} content. These results suggest that the BST glass ceramics could find their potential applications in energy storage capacitor devices.

  3. Spin transport at the international linear collider and its impact on the measurement of polarization

    Energy Technology Data Exchange (ETDEWEB)

    Beckmann, Moritz

    2013-12-15

    At the planned International Linear Collider (ILC), the longitudinal beam polarization needs to be determined with an unprecedented precision. For that purpose, the beam delivery systems (BDS) are equipped with two laser Compton polarimeters each, which are foreseen to achieve a systematic uncertainty of {<=} 0.25 %. The polarimeters are located 1.6 km upstream and 150 m downstream of the e{sup +}e{sup -} interaction point (IP). The average luminosity-weighted longitudinal polarization P{sup lumi}{sub z}, which is the decisive quantity for the experiments, has to be determined from these measurements with the best possible precision. Therefore, a detailed understanding of the spin transport in the BDS is mandatory to estimate how precise the longitudinal polarization at the IP is known from the polarimeter measurements. The envisaged precision for the propagation of the measurement value is {<=} 0.1 %. This thesis scrutinizes the spin transport in view of the achievable precision. A detailed beamline simulation for the BDS has been developed, including the simulation of the beam-beam collisions at the IP. The following factors which might limit the achievable precision is investigated: a variation of the beam parameters, the beam alignment precision at the polarimeters and the IP, the bunch rotation at the IP, the detector magnets, the beam-beam collisions, the emission of synchrotron radiation and misalignments of the beamline elements. In absence of collisions, a precision of 0.085% on the propagation of the measured longitudinal polarization has been found achievable. This result however depends mainly on the presumed precisions for the parallel alignment of the beam at the polarimeters and for the alignment of polarization vector. In presence of collisions, the measurement at the downstream polarimeter depends strongly on the intensity of the collision and the size of the polarimeter laser spot. Therefore, a more detailed study of the laser-bunch interaction is

  4. Evaluation of small wind turbines in distributed arrangement as sustainable wind energy option for Barbados

    International Nuclear Information System (INIS)

    The island of Barbados is 99% dependent on fossil fuel imports to satisfy its energy needs, which is unsustainable. This study proposes a 10 MW distributed wind energy scheme using micro wind turbines (WT) of horizontal (HAWT) and vertical axis (VAWT) configurations. These units are rated less than 500 W, and the scheme is hereafter referred to as mWT10. mWT10 is compared to the proposed 10 MW medium WT farm by the Barbados Light and Power Company (BL and P). The economic bottom line is the levelized cost of electricity (LCOE). The results highlight the BL and P proposal as the best economic option at BDS$0.19 per kWh, while that of both mWT10 configurations exceeds the conventional cost of BDS$0.25 by two to nine times. This is attributed to significantly higher relative installation and operational costs. However, the financial gap between mWT10 LCOE and the retail price of electricity is much smaller due to a large fuel surcharge passed on to each customer. Annual additional benefits of using wind energy include: greenhouse gas emissions savings of 6-23 kt of carbon dioxide; and anavoided fuel costs of BDS$1.5-5.3 million. The distributed mWT10 using HAWTs competes directly with the BL and P farm, however, it provides these benefits without the visual or ecological impacts of the larger machines. Conversely, VAWTs have features that favour a visually discrete and widely repeatable scheme but suffer relatively high costs. Therefore, this study illustrates the great potential of small wind turbines to be competitive with conventional wind farms, thus challenging the small wind industry to meet its potential by producing reliable and robust machines at lower cost. (author)

  5. A HERSCHEL SURVEY OF COLD DUST IN DISKS AROUND BROWN DWARFS AND LOW-MASS STARS

    International Nuclear Information System (INIS)

    We report the complete photometric results from our Herschel study which is the first comprehensive program to search for far-infrared emission from cold dust around young brown dwarfs (BDs). We surveyed 50 fields containing 51 known or suspected BDs and very low mass stars that have evidence of circumstellar disks based on Spitzer photometry and/or spectroscopy. The objects with known spectral types range from M3 to M9.5. Four of the candidates were subsequently identified as extragalactic objects. Of the remaining 47 we have successfully detected 36 at 70 μm and 14 at 160 μm with signal-to-noise ratio (S/N) greater than 3, as well as several additional possible detections with low S/N. The objects exhibit a range of [24]-[70] μm colors suggesting a range in mass and/or structure of the outer disk. We present modeling of the spectral energy distributions of the sample and discuss trends visible in the data. Using two Monte Carlo radiative transfer codes we investigate disk masses and geometry. We find a very wide range in modeled total disk masses from less than 10–6 M☉ up to 10–3 M☉ with a median disk mass of the order of 3 × 10–5 M☉, suggesting that the median ratio of disk mass to central object mass may be lower than for T Tauri stars. The disk scale heights and flaring angles, however, cover a range consistent with those seen around T Tauri stars. The host clouds in which the young BDs and low-mass stars are located span a range in estimated age from ∼1-3 Myr to ∼10 Myr and represent a variety of star-forming environments. No obvious dependence on cloud location or age is seen in the disk properties, though the statistical significance of this conclusion is not strong.

  6. Awareness of Consumer Protection Act among the dental fraternity in India

    Directory of Open Access Journals (Sweden)

    Lingam Amara Swapna

    2016-01-01

    Full Text Available Background: The medical and dental professionals have been included in the Consumer Protection Act (CPA to shield the patients in case of any unethical treatment given by the doctor. Though there is ample literature regarding the CPA and its importance, insufficient data is available from the Indian subcontinent regarding the awareness of dentists in India and the problems faced by them in clinical practice. Thus, there is a need to know the awareness of the dental fraternity in India and their knowledge about CPA. Objective: To evaluate the knowledge, awareness, and practices regarding the CPA among dental professionals in India. Materials and Methods: In a cross-sectional study, a total of 467 dental professionals (198 males, 269 females comprising (117 Bachelor of Dental Surgery (BDS practitioners, (114 Master of Dental Surgery (MDS practitioners, (104 interns, and (79 postgraduate (PG students were surveyed using a self-administered structured electronic questionnaire. The questionnaire comprised 20 questions about the awareness of CPA and whether these professionals were following the recommendations of CPA. Chi-square test was used to know the significance. Results: The CPA awareness scores were significantly higher among MDS practitioners when compared with those of BDS practitioners, interns, and postgraduates. Almost 66% of the participants found the taking of written consent to be time-consuming. Nearly 70% and 69.3% of the BDS and MDS practitioners, respectively, were updating the medical ethics. Conclusion: Considering the present scenario, a better understanding of CPA is necessary for dentists in order to be on the safer side and an educational program would be helpful to increase the knowledge and confidence of dentists in any medical legal jurisprudence to avoid any litigation.

  7. Rat Cardiomyocytes Express a Classical Epithelial Beta-Defensin

    Directory of Open Access Journals (Sweden)

    Annika Linde

    2008-01-01

    Full Text Available Beta-defensins (BDs are classical epithelial antimicrobial peptides of immediate importance in innate host defense. Since recent studies have suggested that certain BDs are also expressed in non-traditional tissues, including whole heart homogenate and because effector molecules of innate immunity and inflammation can influence the development of certain cardiovascular disease processes, we hypothesized that BDs are produced by cardiomyocytes as a local measure of cardioprotection against danger signals. Here we report that at least one rat beta-defensin, rBD1, is expressed constitutively in cardiomyocytes specifically isolated using position-ablation-laser-microdissection (P.A.L.M. Microlaser Technologies. RT-PCR analysis showed expression of a single 318 bp transcript in adult rat heart (laser-excised cardiomyocytes and H9c2 cells (neonatal rat heart myoblasts. Moreover, the full length cDNA of rBD1 was established and translated into a putative peptide with 69 amino acid residues. The predicted amino acid sequence of the adult rat cardiac BD-1 peptide displayed 99% identity with the previously reported renal rBD1 and 88, 53, 53 and 50% identity with mouse, human, gorilla and rhesus monkey BD1 respectively. Furthermore, structural analysis of the cardiac rBD1 showed the classical six-cysteine conserved motif of the BD family with an alpha-helix and three beta-sheets. Additionally, rBD1 displayed a significantly greater number of amphoteric residues than any of the human analogs, indicating a strong pH functional dependence in the rat. We suggest that rBD1, which was initially believed to be a specific epithelium-derived peptide, may be also involved in local cardiac innate immune defense mechanisms.

  8. Age, puberty, body dissatisfaction, and physical activity decline in adolescents. Results of the German Health Interview and Examination Survey (KiGGS

    Directory of Open Access Journals (Sweden)

    Finne Emily

    2011-10-01

    Full Text Available Abstract Background Physical activity (PA shows a marked decline during adolescence. Some studies have pointed to pubertal status or timing as possible PA determinants in this age group. Furthermore, it was supposed that the impact of pubertal changes on PA might be mediated by psychological variables like body dissatisfaction (BDS. Methods The 11- to 17-year-old subsample of the German Health Interview and Examination Survey (KiGGS was used (n = 6 813; 51.3% male, response rate = 66.6%. Through sex-specific sequential multinomial logistic regressions we analysed the univariate and independent associations of chronological age, absolute pubertal status, relative pubertal timing, and BDS with the frequency of PA. Results Chronological age showed a significantly negative association with PA in both sexes, independent of puberty. The odds of inactivity in contrast to nearly daily PA increased about 70% in boys and 35% in girls for each year of age, respectively. Adjusted for age and other possible confounders, inactivity was significantly less likely for boys in late pubertal stages (OR = 0.27, 95% CI = 0.09-0.78. The risk of inactivity was more than doubled in boys maturing earlier than peers in terms of relative pubertal timing (OR = 2.20, 95% CI = 1.36-3.56. No clear significant puberty effects were found in girls, but the inactivity was more likely for those with irregular menstruation (OR = 1.71, 95% CI = 1.06-2.75. BDS also contributed to the prediction of PA in both sexes. It partially mediated puberty effects in boys but not in girls. Conclusions Overall, chronological age was a far more important predictor of PA in German adolescents than absolute pubertal status or relative pubertal timing. Further possible explanatory variables like sociocultural influences, social support or increasing time requirements for education should be analysed in conjunction with chronological age in future studies.

  9. Effect of meta-carborane on segmental dynamics in a bimodal Poly(dimethylsiloxane) network

    Energy Technology Data Exchange (ETDEWEB)

    Lewicki, J; Maxwell, R S; Patel, M; Herberg, J; Swain, A C; Liggat, J; Pethrick, R

    2008-06-11

    Bimodal networks of polydimethylsiloxane (PDMS) filled with varying amounts of icosahedral meta-carborane (m-CB) have been developed and characterized by broadband dielectric spectroscopy (BDS) and static {sup 1}H Multiple Quantum Nuclear Magnetic Resonance (MQ NMR). Both BDS and MQ NMR showed evidence for a decrease in the polymer chain dynamics. BDS spectra quantified a normal-mode relaxation near 40 Hz at 40 C. The frequency maximum observed for filled samples decreased with increasing m-CB content until contents greater than 5 wt. %. The width of the relaxation spectrum increased with the addition of small quantities of filler and decreased with filler contents greater that 5 wt. %. Agglomeration effects were observed at loadings greater than 5 wt % as manifest by the onset of low frequency Maxwell-Wagner-Sillars (MWS) processes. The MQ NMR data allowed the characterization of distributions of the residual dipolar couplings, <{Omega}{sub d}> and thus in the dynamic order parameter, Sb, consistent with the bimodal network architecture expected from the synthesis protocol used. Upon addition of less than 10 wt.% m-CB filler, the mean <{Omega}{sub d}> for the longer chains increased by 46% and the width of the distribution increased by 33%. The mean <{Omega}{sub d}> for the shorter chains increased by much less, indicative of preferential dispersion of the filler particles in the long chain domains of the network structure. We conclude that the mechanism of reinforcement is likely a free volume space filling at low loadings transitioning to complex molecular filler and polymer chain interaction phenomena at higher loadings.

  10. Evaluation of small wind turbines in distributed arrangement as sustainable wind energy option for Barbados

    Energy Technology Data Exchange (ETDEWEB)

    Bishop, Justin D.K.; Amaratunga, Gehan A.J. [University of Cambridge, Department of Engineering, 9 JJ Thomson Avenue, Cambridge CB3 0FA, England (United Kingdom)

    2008-06-15

    The island of Barbados is 99% dependent on fossil fuel imports to satisfy its energy needs, which is unsustainable. This study proposes a 10 MW distributed wind energy scheme using micro wind turbines (WT) of horizontal (HAWT) and vertical axis (VAWT) configurations. These units are rated less than 500 W, and the scheme is hereafter referred to as mWT10. mWT10 is compared to the proposed 10 MW medium WT farm by the Barbados Light and Power Company (BL and P). The economic bottom line is the levelized cost of electricity (LCOE). The results highlight the BL and P proposal as the best economic option at BDS$0.19 per kWh, while that of both mWT10 configurations exceeds the conventional cost of BDS$0.25 by two to nine times. This is attributed to significantly higher relative installation and operational costs. However, the financial gap between mWT10 LCOE and the retail price of electricity is much smaller due to a large fuel surcharge passed on to each customer. Annual additional benefits of using wind energy include: greenhouse gas emissions savings of 6-23 kt of carbon dioxide; and anavoided fuel costs of BDS$1.5-5.3 million. The distributed mWT10 using HAWTs competes directly with the BL and P farm, however, it provides these benefits without the visual or ecological impacts of the larger machines. Conversely, VAWTs have features that favour a visually discrete and widely repeatable scheme but suffer relatively high costs. Therefore, this study illustrates the great potential of small wind turbines to be competitive with conventional wind farms, thus challenging the small wind industry to meet its potential by producing reliable and robust machines at lower cost. (author)

  11. Production and characterization of a novel yeast extracellular invertase activity towards improved dibenzothiophene biodesulfurization

    OpenAIRE

    Arez, B. F.; Alves, Luís Manuel; Paixão, Susana M.

    2014-01-01

    The main goal of this work was the production and characterization of a novel invertase activity from Zygosaccharomyces bailii strain Talf1 for further application to biodesulfurization (BDS) in order to expand the exploitable alternative carbon sources to renewable sucrose-rich feedstock. The maximum invertase activity (163 U ml.1) was achieved after 7 days of Z. bailii strain Talf1 cultivation at pH 5.5–6.0, 25 °C, and 150 rpm in Yeast Malt Broth with 25 % Jerusalem artichoke pulp as in...

  12. Issues of Stability and Ground Motion in ILC

    Energy Technology Data Exchange (ETDEWEB)

    Seryi, Andrei; Hendrickson, Linda; White, Glen; /SLAC

    2006-02-03

    Stability of International Linear Collider is determined by the stability of the site, additional noises of beamline component, energy and kicker jitter, and performance of train-to-train and intratrain feedback. Stability goals in terms of the beam jitter at the end of the linac, in BDS and at the IP are discussed in this paper, and translated to stability goals for the site and for component jitter. Present status of stability studies is reviewed and feasibility of achieving the stability goals is discussed.

  13. Determination of Vitamin B12 in Vitamin B12 Compound Ointment- Ⅰ by HPLC%复方维生素B12软膏Ⅰ号中维生素B12的HPLC测定

    Institute of Scientific and Technical Information of China (English)

    杨谊; 李兵; 史学慧

    2004-01-01

    建立了HPLC法测定复方维生素B12软膏Ⅰ号中维生素B12的含量.采用Hypersll BDS C18柱,流动相为乙腈-0.05mol/L磷酸二氢钾溶液(15:85),检测波长360nm.维生素B12在0.16~0.8μg范围内线性关系良好(r=0.9995),平均回收率为98.4%,RSD为0.9%.

  14. Analytic structure of the n=7 scattering amplitude in N=4 SYM theory at multi-Regge kinematics. Conformal Regge pole contribution

    Energy Technology Data Exchange (ETDEWEB)

    Bartels, Jochen; Kormilitzin, Andrey [Hamburg Univ. (Germany). II. Inst. fuer Theoretische Physik; Lipatov, Lev [Hamburg Univ. (Germany). II. Inst. fuer Theoretische Physik; St. Petersburg Nuclear Physics Institute, St. Petersburg (Russian Federation)

    2013-11-15

    We investigate the analytic structure of the 2 {yields} 5 scattering amplitude in the planar limit of N=4 SYM in multi-Regge kinematics in all physical regions. We demonstrate the close connection between Regge pole and Regge cut contributions: in a selected class of kinematic regions (Mandelstam regions) the usual factorizing Regge pole formula develops unphysical singularities which have to be absorbed and compensated by Regge cut contributions. This leads, in the corrections to the BDS formula, to conformal invariant 'renormalized' Regge pole expressions in the remainder function. We compute these renormalized Regge poles for the 2 {yields} 5 scattering amplitude.

  15. Development and Validation of a Stability-Indicating Assay of Etofenamate by RP-HPLC and Characterization of Degradation Products

    OpenAIRE

    Peraman, Ramalingam; Nayakanti, Devanna; Dugga, Hari Hara Theja; Kodikonda, Sudhakara

    2013-01-01

    A validated stability-indicating RP-HPLC method for etofenamate (ETF) was developed by separating its degradation products on a C18 (250 mm × 4.6 mm 5 μm) Qualisil BDS column using a phosphate buffer (pH-adjusted to 6.0 with orthophosphoric acid) and methanol in the ratio of 20:80 % v/v as the mobile phase at a flow rate of 1.0 mL/min. The column effluents were monitored by a photodiode array detector set at 286 nm. The method was validated in terms of specificity, linearity, accuracy, precis...

  16. Gasoline Biodesulfurization DE-FC07-97ID13570 FINAL REPORT; FINAL

    International Nuclear Information System (INIS)

    Nine strains were identified to grow with gasoline as sole sulfur source. Two different genes were cloned from Gordonia terrae KGB1 and tested for the ability to support gasoline BDS. The first of these, fmoA, was cloned by screening a KGB1 gene library for the ability to convert indole to indigo (a sulfur-regulated capability in KGB1). The fmoA gene was overexpressed in a gasoline tolerant strain of Pseudomonas putida PpG1 and the recombinant strain was shown to convert thiophene to a dimer of thiophene sulfoxide at rates nearly two orders of magnitude higher than KGB1 could catalyze the reaction. Despite this high activity the recombinant PpG1 was unable to demonstrate any activity against gasoline either in shake flask or in bench-scale gasoline BDS bioreactor. A second gene (toeA) was cloned from KGB1 and shown to support growth of Rhodococcus erythropolis JB55 on gasoline. The toeA gene was also identified in another gasoline strain T. wratislaviensis EMT4, and was identified as a homolog of dszA from R. erythropolis IGTS8. Expression of this gene in JB55 supported conversion of DBTO2 (the natural substrate for DszA) to HPBS, but activity against gasoline was low and BDS results were inconsistent. It appeared that activity was directed against C2- and C3-thiophenes. Efforts to increase gene expression by plasmid manipulation, by addition of flavin reductase genes, or by expression in PpG1 were unsuccessful. The DszC protein (DBT monooxygenase) from IGTS8 has very little activity against the sulfur compounds in gasoline, but a mutant enzyme with a substitution of phenylalanine for valine at position 261 was shown to have an altered substrate range. This alteration resulted in increased activity against gasoline, with activity towards mainly C3- and C4-thiophenes and benzothiophene. A mutant library of dszB was constructed by RACHITT (W. C. Coco et al., DNA shuffling method for generating highly recombined genes and evolved enzymes. 2001. Nature Biotech. 19

  17. Development of a Stability-Indicating RP-HPLC Method for the Determination of Rupatadine and its Degradation Products in Solid Oral Dosage Form

    OpenAIRE

    Trivedi, Harshal Kanubhai; Mukesh C. Patel

    2012-01-01

    A simple, sensitive, and reproducible reversed-phase high-performance liquid chromatography (RP-HPLC) method, coupled with a photodiode array detector, was developed for the determination of rupatadine (RUPA) and its related substances in pharmaceutical dosage forms. Chromatographic separation was achieved on the Hypersil BDS (150 x 4.6 mm, 5 μm) column with a mobile phase containing a gradient mixture of a buffer (acetate buffer pH-6.0) and solvent (methanol). The eluted compounds were monit...

  18. Electrophysical behavior of ion-conductive organic-inorganic polymer system based on aliphatic epoxy resin and salt of lithium perchlorate

    OpenAIRE

    Matkovska, Liubov; Iurzhenko, Maksym; Mamunya, Yevgen; Matkovska, Olga; Demchenko, Valeriy; Lebedev, Eugene; Boiteux, Gisele; Serghei, Anatoli

    2014-01-01

    Abstract In the present work, ion-conductive hybrid organic-inorganic polymers based on epoxy oligomer of diglycide aliphatic ester of polyethylene glycol (DEG) and lithium perchlorate (LiClO4) were synthesized. The effect of LiClO4 content on the electrophysical properties of epoxy polymers has been studied by differential scanning calorimetry (DSC) and broadband dielectric spectroscopy (BDS). The effect of LiClO4 content on the structure has been studied by wide-angle X-ray scattering (WAXS...

  19. Tuning of the Compact Linear Collider Beam Delivery System

    CERN Document Server

    Garcia, H; Inntjore Levinsen, Y; Latina, A; Tomas, R; Snuverink, J

    2014-01-01

    Tuning the Compact Linear Collider (CLIC) BeamDelivery System (BDS), and in particular the Final Focus (FF), is a challenging task. In simulations without misalignments, the goal is to reach 120%o f the nominal luminosity target, in order to allow for 10% loss due to static imperfections, and another 10% loss from dynamic imperfections. Various approaches have been considered to correct the magnet misalignments, including 1-1 correction, Dispersion Free Steering (DFS), and several minimization methods utilizing multipole movers. In this paper we report on the recent advancements towards a feasible tuning approach that reaches the required luminosity target.

  20. Emission Rates and Optical Properties of Pollutants Emitted from a Traditional and an Improved Wood-Burning Cookstove

    Science.gov (United States)

    Kirchstetter, T.; Hadley, O. L.; Preble, C.; Gadgil, A.

    2010-12-01

    Traditional cooking methods in developing regions of the world generate gas and particle phase pollutants that endanger the lives of more than a billion people and contribute appreciably to the burden of climate-changing particles in the atmosphere. This presentation compares pollutant emissions from the traditional “three-stone fire” and an improved cookstove developed for refugees in Darfur: the Berkeley-Darfur Stove (BDS). The BDS was designed for increased fuel efficiency to decrease the risk of assault that women often face when gathering fuel wood. Reduced pollutant exposure and climate impact are potential co-benefits. Testing of these stoves at the Lawrence Berkeley National Laboratory facility includes 1-Hz measurements of concentrations of particulate matter, black carbon, carbon monoxide, and carbon dioxide; coefficients of particle light absorption and scattering; and absorption Angstrom exponent. Absorption and scattering coefficients were measured at 532 nm using a photoacoustic absorption instrument equipped with a reciprocal nephelometer. The BDS heated food faster and consumed less wood in cooking tests compared to the three-stone fire. The BDS emitted less carbon monoxide and particulate matter but comparable mass of black carbon compared to the three-stone fire for the same cooking task. Values of the absorption Angstrom exponent ranged from about 1 - 3, indicating the emission of both black carbon and light-absorbing organic carbon (i.e., brown carbon). Values of (dry) aerosol single scattering albedo were mostly in the range of 0.25 - 0.55, indicating that the emitted particles tend to absorb more light than they scatter. Our analysis considered the variability of pollutant emissions during different phases of the fire. Particulate matter emissions were highest during the first several minutes of cooking, which included igniting the wood, whereas carbon monoxide emissions were highest during the last several minutes of cooking when

  1. Determination of racecadotril by HPLC in capsules

    OpenAIRE

    Prabu S; Singh T; Joseph A; Kumar C; Shirwaikar A

    2007-01-01

    A simple, precise and rapid RP-HPLC method was developed for the determination of racecadotril in a pharmaceutical formulation using gemfibrozil as internal standard. Ratio of the peak area of analyte to internal standard was used for quantification. The chromatographic separation was carried out by using a Reverse Phase C18 column (BDS-Hypersil). The mobile phase consisting of a mixture of 20 mM phosphate buffer (pH 3.5) and acetonitrile in the ratio of (40:60) with detection at 230 nm at a ...

  2. Determination of the Flavonoids from Ginkgo Biloba Extract by High Performance Liquid Chromatography

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    HPLC method for analysis of the flavonoids from ginkgo biloba extract (GBE) was studied. By suitable selection of columns, symmetrical chromatographic peaks were obtained without using acidic modifier in the mobile phase, which can eliminate the time for cleaning the chromatographic system and simplify the analystic method for GBE. Experimental conditions: column: Hypersil BDS C18,5(m×4×250 mm; column temperature: 35(C; mobile phase: 46% methanol-54% water; flow rate: 0.7 mL/min; detection wavelength: 360nm.

  3. Academic advising and student support: Help-seeking behaviors among Saudi dental undergraduate students

    OpenAIRE

    Asim Al-Ansari; Maha El Tantawi; Maha AbdelSalam; Fahad Al-Harbi

    2015-01-01

    Objective: The purpose of this study was to assess the use of and satisfaction with the academic-advising and student-support systems available to undergraduate students in the College of Dentistry at the University of Dammam. In addition, the study aimed to also identify factors that explained the help-seeking behavior of students which they used to solve academic issues. Materials and methods: Students enrolled in the five-year Bachelor of Dental Surgery (BDS) program in 2012–13 and 2013...

  4. The Multi-source Synchronization System of Power System

    Directory of Open Access Journals (Sweden)

    Gangjun Gong

    2013-09-01

    Full Text Available Since the power system frequency and time synchronization network are networking alone, which brings a lot of system synchronization, reliability and security issues, this article will merge frequency synchronization network and time synchronization network into one to set up the synchronization system of power grid. In this paper, we present a new generation of power synchronization network program with BDS and GPS timing as the cure. Meanwhile, it presents a three-level power system synchronized demonstration network which is consist of provincial power grid, municipal power grid and substations. And Iin the end, we conduct some research on related technologies of this program.

  5. Gasoline Biodesulfurization DE-FC07-97ID13570 FINAL REPORT

    Energy Technology Data Exchange (ETDEWEB)

    Pienkos, Philip T.

    2002-01-15

    Nine strains were identified to grow with gasoline as sole sulfur source. Two different genes were cloned from Gordonia terrae KGB1 and tested for the ability to support gasoline BDS. The first of these, fmoA, was cloned by screening a KGB1 gene library for the ability to convert indole to indigo (a sulfur-regulated capability in KGB1). The fmoA gene was overexpressed in a gasoline tolerant strain of Pseudomonas putida PpG1 and the recombinant strain was shown to convert thiophene to a dimer of thiophene sulfoxide at rates nearly two orders of magnitude higher than KGB1 could catalyze the reaction. Despite this high activity the recombinant PpG1 was unable to demonstrate any activity against gasoline either in shake flask or in bench-scale gasoline BDS bioreactor. A second gene (toeA) was cloned from KGB1 and shown to support growth of Rhodococcus erythropolis JB55 on gasoline. The toeA gene was also identified in another gasoline strain T. wratislaviensis EMT4, and was identified as a homolog of dszA from R. erythropolis IGTS8. Expression of this gene in JB55 supported conversion of DBTO2 (the natural substrate for DszA) to HPBS, but activity against gasoline was low and BDS results were inconsistent. It appeared that activity was directed against C2- and C3-thiophenes. Efforts to increase gene expression by plasmid manipulation, by addition of flavin reductase genes, or by expression in PpG1 were unsuccessful. The DszC protein (DBT monooxygenase) from IGTS8 has very little activity against the sulfur compounds in gasoline, but a mutant enzyme with a substitution of phenylalanine for valine at position 261 was shown to have an altered substrate range. This alteration resulted in increased activity against gasoline, with activity towards mainly C3- and C4-thiophenes and benzothiophene. A mutant library of dszB was constructed by RACHITT (W. C. Coco et al., DNA shuffling method for generating highly recombined genes and evolved enzymes. 2001. Nature Biotech. 19

  6. Observation of Ds1(2536)+ -> D+pi-K+ and angular decomposition of Ds1(2536)+ -> D*+K0S

    CERN Document Server

    Balagura, V; Aihara, H; Arinstein, K; Aulchenko, V; Aushev, T; Bakich, A M; Barberio, E; Bay, A; Belous, K S; Bhardwaj, V; Bitenc, U; Bondar, A; Bozek, A; Bracko, M; Brodzicka, J; Browder, T E; Chang, M C; Chao, Y; Chen, A; Chen, W T; Cheon, B G; Chistov, R; Cho, I S; Choi, Y; Dalseno, J; Danilov, M; Drutskoy, A; Eidelman, S; Epifanov, D; Gabyshev, N; Garmash, A; Golob, B; Ha, H; Haba, J; Hara, T; Hastings, N C; Hayasaka, K; Hayashii, H; Hazumi, M; Heffernan, D; Hoshi, Y; Hou, W S; Hyun, H J; Inami, K; Ishikawa, A; Ishino, H; Itoh, R; Iwasaki, M; Iwasaki, Y; Kah, D H; Kaji, H; Katayama, N; Kawai, H; Kawasaki, T; Kichimi, H; Kim, H J; Kim, H O; Kim, Y J; Kinoshita, K; Korpar, S; Krizan, P; Krokovny, P; Kuo, C C; Kuzmin, A; Kwon, Y J; Lange, J S; Lee, M J; Lee, S E; Lesiak, T; Limosani, A; Lin, S W; Liu, Y; Liventsev, D; Mandl, F; McOnie, S; Medvedeva, T; Mitaroff, W A; Miyake, H; Miyata, H; Miyazaki, Y; Mizuk, R; Mohapatra, D; Moloney, G R; Nagasaka, Y; Nakano, E; Nakao, M; Nakazawa, H; Natkaniec, Z; Nishida, S; Nitoh, O; Ogawa, S; Ohshima, T; Okuno, S; Olsen, S L; Ostrowicz, W; Ozaki, H; Pakhlov, P; Pakhlova, G; Palka, H; Park, C W; Peak, L S; Pestotnik, R; Piilonen, L E; Sakai, Y; Schneider, O; Senyo, K; Shapkin, M; Shen, C P; Shibuya, H; Shiu, J G; Somov, A; Stanic, S; Staric, M; Sumiyoshi, T; Tamai, K; Tanaka, M; Taylor, G N; Teramoto, Y; Tikhomirov, I; Uehara, S; Ueno, K; Uglov, T; Unno, Y; Uno, S; Urquijo, P; Usov, Yu; Varner, G; Vervink, K; Villa, S; Vinokurova, A; Wang, C C; Wang, C H; Wang, M Z; Wang, P; Wang, X L; Watanabe, Y; Won, E; Yabsley, B D; Yamaguchi, A; Yamashita, Y; Yamauchi, M; Zhang, Z P; Zhilich, V; Zhulanov, V; Zupanc, A; Zyukova, O

    2007-01-01

    Using 462/fb of e+e- annihilation data recorded by the Belle detector, we report the first observation of the decay Ds1(2536)+ -> D+pi-K+. The ratio of branching fractions B(Ds1+ -> D+pi-K+)/B(Ds1+ -> D*+K0) is measured to be (3.27+-0.18+-0.37)%. We also study the angular distributions in the Ds1(2536)+ -> D*+K0S decay and measure the ratio of D- and S-wave amplitudes. The S-wave dominates, with a partial width of Gamma_S/Gamma_total=0.72+-0.05+-0.01.

  7. First Observation of the Decay D_s^+ to proton anti-neutron

    CERN Document Server

    Athar, S B; Yelton, J; Rubin, P; Eisenstein, B I; Karliner, I; Mehrabyan, S; Lowrey, N; Selen, M; White, E J; Wiss, J; Mitchell, R E; Shepherd, M R; Besson, D; Pedlar, T K; Cronin-Hennessy, D; Gao, K Y; Hietala, J; Kubota, Y; Klein, T; Lang, B W; Poling, R; Scott, A W; Zweber, P; Dobbs, S; Metreveli, Z; Seth, K K; Tomaradze, A G; Libby, J; Powell, A; Wilkinson, G; Ecklund, K M; Love, W; Savinov, V; López, A; Méndez, H; Ramírez, J; Ge, J Y; Miller, D H; Shipsey, I P J; Xin, B; Adams, G S; Anderson, M; Cummings, J P; Danko, I; Hu, D; Moziak, B; Napolitano, J; He, Q; Insler, J; Muramatsu, H; Park, C S; Thorndike, E H; Yang, F; Artuso, M; Blusk, S; Khalil, S; Li, J; Mountain, R; Nisar, S; Randrianarivony, K; Sultana, N; Skwarnicki, T; Stone, S; Wang, J C; Zhang, L M; Bonvicini, G; Cinabro, D; Dubrovin, M; Lincoln, A; Naik, P; Rademacker, J; Asner, D M; Edwards, K W; Reed, J; Briere, R A; Ferguson, T; Tatishvili, G; Vogel, H; Watkins, M E; Rosner, J L; Alexander, J P; Cassel, D G; Duboscq, J E; Ehrlich, R; Fields, L; Gibbons, L; Gray, R; Gray, S W; Hartill, D L; Heltsley, B K; Hertz, D; Hunt, J M; Kandaswamy, J; Kreinick, D L; Kuznetsov, V E; Ledoux, J; Mahlke-Krüger, H; Mohapatra, D; Onyisi, P U E; Patterson, J R; Peterson, D; Riley, D; Ryd, A; Sadoff, A J; Shi, X; Stroiney, S; Sun, W M; Wilksen, T

    2008-01-01

    Using e^+e^- -> D_s^*+ D_s^- data collected near the peak D_s production energy, E_cm=4170 MeV, with the CLEO-c detector, we present the first observation of the decay D_s^+ -> proton anti-neutron. We measure a branching fraction B(D_s^+ -> p anti-n = (1.30 +- 0.36 +0.12 -0.16) x 10^-3. This is the first observation of a charmed meson decaying into a baryon-antibaryon final state.

  8. Absolute Measurement of Hadronic Branching Fractions of the D_s^+ Meson

    CERN Document Server

    Alexander, J; Cassel, D G; Duboscq, J E; Ehrlich, R; Fields, L; Gibbons, L; Gray, R; Gray, S W; Hartill, D L; Heltsley, B K; Hertz, D; Jones, C D; Kandaswamy, J; Kreinick, D L; Kuznetsov, V E; Mahlke-Krüger, H; Mohapatra, D; Onyisi, P U E; Patterson, J R; Peterson, D; Riley, D; Ryd, A; Sadoff, A J; Shi, X; Stroiney, S; Sun, W M; Wilksen, T; Athar, S B; Patel, R; Yelton, J; Rubin, P; Eisenstein, B I; Karliner, I; Mehrabyan, S; Lowrey, N; Selen, M; White, E J; Wiss, J; Mitchell, R E; Shepherd, M R; Besson, D; Pedlar, T K; Cronin-Hennessy, D; Gao, K Y; Hietala, J; Kubota, Y; Klein, T; Lang, B W; Poling, R; Scott, A W; Zweber, P; Dobbs, S; Metreveli, Z; Seth, K K; Tomaradze, A G; Libby, J; Powell, A; Wilkinson, G; Ecklund, K M; Love, W; Savinov, V; López, A; Méndez, H; Ramírez, J; Ge, J Y; Miller, D H; Sanghi, B; Shipsey, I P J; Xin, B; Adams, G S; Anderson, M; Cummings, J P; Danko, I; Hu, D; Moziak, B; Napolitano, J; He, Q; Insler, J; Muramatsu, H; Park, C S; Thorndike, E H; Yang, F; Artuso, M; Blusk, S; Khalil, S; Li, J; Mountain, R; Nisar, S; Randrianarivony, K; Sultana, N; Skwarnicki, T; Stone, S; Wang, J C; Zhang, L M; Bonvicini, G; Cinabro, D; Dubrovin, M; Lincoln, A; Rademacker, J; Asner, D M; Edwards, K W; Naik, P; Briere, R A; Ferguson, T; Tatishvili, G; Vogel, H; Watkins, M E; Rosner, J L

    2008-01-01

    The branching fractions of D_s meson decays serve to normalize many measurements of processes involving charm quarks. Using 298 /pb of e+ e- collisions recorded at a center of mass energy of 4.17 GeV, we determine absolute branching fractions for eight D_s decays with a double tag technique. In particular we determine the branching fraction B(D_s -> K- K+ pi+) = (5.50 +- 0.23 +- 0.16)%, where the uncertainties are statistical and systematic respectively. We also provide partial branching fractions for kinematic subsets of the K- K+ pi+ decay mode.

  9. Total cross sections of beauty and charmed mesons on protons

    International Nuclear Information System (INIS)

    Using a simple scaling law we predict the values of the total cross sections σ(B±p), σBd,s0, σ(bar Bd,s0P), σ(Dd,s±P), σ(D0p), σ(bar D0p) from known total Kp cross sections. We assume that mesons with the same light valence quark, q, and differing only by their heavy valence quark content, Q, have total cross sections on protons which scale as the inverse of the nth power of the reduced mass of the meson. We predict that σ(Q bar q)p > σ(bar Qq)p

  10. CLIC Muon Sweeper Design

    CERN Document Server

    Aloev, A; Gatignon, L; Modena, M; Pilicer, B; Tapan, I

    2016-01-01

    There are several background sources which may affect the analysis of data and detector performans at the CLIC project. One of the important background source is halo muons, which are generated along the beam delivery system (BDS), for the detector performance. In order to reduce muon background, magnetized muon sweepers have been used as a shielding material that is already described in a previous study for CLIC [1]. The realistic muon sweeper has been designed with OPERA. The design parameters of muon sweeper have also been used to estimate muon background reduction with BDSIM Monte Carlo simulation code [2, 3].

  11. Comparison of anatomical characteristics of leaves and flowers of Crataegus and some species of Rosaceae family

    Directory of Open Access Journals (Sweden)

    V.A. Kiryanova

    2014-04-01

    Full Text Available The present work shows the results of microscopy of Crataegus sanguinea Pall. leaves with flowers (Crataegi flores cum folia, which is considered as a perspective form of medicinal raw material, and the hypothetical plant adulterants – Amelanchier ovalis Medik., Prunus subgen. Cerasus (Mill. A. Gray, Pyrus communis L., Aronia melanocarpa (Michx. Elliott (Rosaceae. Parts of leaves and flowers of stated plants were subjected to anatomical investigation and comparative studies. Microscopical characteristics of leaves and flowers, which make possible to distinguish Crataegus from other species, were detected. The obtained data can be applied for the development of pharmacopoeial article “Crataegi Flores cum folia” for the XII edition of the Russian State Pharmacopoeia.

  12. [Fungi isolated from diseased medicinal plants].

    Science.gov (United States)

    Sato, T; Matsuhashi, M; Iida, O

    1992-01-01

    One hundred and forty-four fungal isolates were obtained from diseased Paeonia albiflora Pall. var. trichocarpa Bung., Astragalus membranaceus Bung., Lithospermum erythrorhizon Sieb. et Zucc., Ledebouriella seseloides Wolff and Bupleurum falcatum L. which were collected in the test field of Tsukuba Medicinal Plant Research Station, National Institute of Hygienic Sciences. Most of them were identified into 15 genera containing 8 species. Fungal species presumed to be pathogens of the host plants were as follows: Cladosporium paeoniae, Pestalotia paeoniicola, Glomerella cingulata, Hainesia lythri, Guignardia sp. and Alternaria sp. from P. albiflora, Fusarium spp., Rhizoctonia spp. and Neocosmospora vasinfecta from A. membranaceus, Colletotrichum gloeosporioides from L. erythrorhizon, Rhizoctonia sp., Fusarium spp., Phoma sp. and Pyrenochaeta sp. from L. seseloides, and Fusarium sp., Alternaria alternata, Phyllosticta sp., Phoma sp., Phomopsis sp. and C. gloeosporioides from B. falcatum. Roots of B. falcatum were found to be parasitized by Meloidogyne sp. PMID:1364438

  13. The Effects of Zebra Mussels (Dreissena polymorpha) on the Foraging Success of Eurasian Perch (Perca fluviatilis) and Ruffe (Gymnocephalus cernuus)

    Science.gov (United States)

    Dieterich, Axel; Mörtl, Martin; Eckmann, Reiner

    2004-07-01

    Complex habitat structures can influence the foraging success of fish. Competition for food between fish species can therefore depend on the competitors' abilities to cope with structural complexity. In laboratory experiments, we comparatively assessed effects of zebra mussels (Dreissena polymorpha Pall.) on the foraging success of Eurasian perch (Perca fluviatilis L.) and ruffe (Gymnocephalus cernuus (L.)). In single-species and mixed-species experiments, the fish were fed caddisfly larvae (Tinodes waeneri (L.)) over complex (mussel-covered stones) and less-complex (bare stones) substrates. With intraspecific competition, food consumption by perch and ruffe decreased significantly when the complex substrate was used. With interspecific competition, food consumption by perch and ruffe did not change with substrate complexity, but perch clearly out-competed ruffe on both substrates. Zebra mussel beds provide a refuge for macrozoobenthos against predation by ruffe and probably also by perch. (

  14. 威灵仙的成分、药理活性和临床应用的研究进展

    Institute of Scientific and Technical Information of China (English)

    赵燕强; 杨立新; 张宪民; 邱明华

    2008-01-01

    本文对中药威灵仙的有关研究进行了综述.主要为威灵仙(Clematis chinensis Osbeck)、棉团铁线莲(Clematis hexapetala Pall.)和东北铁线莲(Clematis manshurica Rupr.)成分中发现的化合物.包括皂甙、黄酮、挥发油等,并对新发现的药理作用进行阐述,也说明了治疗一些疾病的机制和起作用的化合物,还对威灵仙的临床应用进行了介绍.

  15. 9种铁线莲属药用植物的比较鉴别

    Institute of Scientific and Technical Information of China (English)

    胡玉涛; 周政昆

    2002-01-01

    @@ 毛茛科铁线莲属植物约有300种,我国有108种[1].其中作为正品威灵仙入药的为威灵仙Clematis chinesis Osbeck、棉团铁线莲Clematis hexapetala Pall.和东北铁线莲Clematis manshurica Rupr.的干燥根及根茎[2].目前市场上作为威灵仙流通的药材种类较多,而且性状相似,难以区别.现对9种铁线莲属药用植物的形态进行比较、鉴别,为今后的研究提供依据.

  16. 蒙药才棉团铁线莲化学成分和药理研究进展

    Institute of Scientific and Technical Information of China (English)

    巴达日呼; 房玉良

    2009-01-01

    蒙药才棉团铁线莲clematis hexapetala pall.具有破痞,调温, "协日乌紊",止腐,消肿,止泻之功效.临床上主治寒痞,消化不良,寒性"协日乌素"病,"吾雅曼"病,黄水疮,疮疡,水肿,寒泻,祛除各种瘤的功效.所含的化学成分黄酮类、糖类、皂苷类、白头翁索、生物碱、挥发油和药理作用抗肿瘤、降血压、降糖、抑菌,抗氧化等作用.

  17. Aerobic biotrickling filtration for biogas desulfurization

    OpenAIRE

    Monzón Montebello, Andrea

    2013-01-01

    Es va gestionar l'operació d'un biofiltre percolador (BTF) durant un període total de 990 dies per a la dessulfuració d'un biogàs sintètic contenint 2,000 ppmv d’H2S (≈ 50 g S-H2S·m-3·h-1), utilitzant un material de rebliment aleatori (anelles Pall d'acer inoxidable). Després de l'optimització de l'operació a pH neutre, es va estudiar l'eliminació simultània de metilmercaptà (CH3SH) i H2S. A continuació es va executar la transició ininterrompuda des de 440 dies a pH neutre (6.0 – 6.5) a 550 d...

  18. "edo jal̀qkina üts̀varòkaetus ma vaelda ..." : [luuletused] / Andreas Kalkun

    Index Scriptorium Estoniae

    Kalkun, Andreas, 1977-

    2002-01-01

    Sisu: "edo jal̀qkina üts̀varòkaetus ma vaelda ..." ; "tsirguq ku kiviq no satassõ taivast aràlaq ..." ; "vahtsõq silmäq pitsitä pääluu sisse ..." ; "tõppõ tõmmat haigõst ma haarõt jal̀ki ..." ; "arsatas njago sisse aigopiteh ..." ; "rühkeq yks jumalat pallõlda jaloh ..." ; "mu süä om no süüdläne täǹtäseq kuvvõ ..." ; "halvaq haavaq häitsese veiga silmih. Eluloolisi andmeid autori kohta lk. 379

  19. Anmeldelser

    Directory of Open Access Journals (Sweden)

    Mikkel Leth Jespersen

    2010-11-01

    Full Text Available Anmeldelser af:Erik Fischer, Michael Bøgh Rasmussen, Ernst Jonas Bencard: Melchior Lorck. Bd. 1-4. Forlaget Vandkunsten, 2009.Ulrik Langen: Den afmægtige – en biografi om Christian 7. Jyllands-Postens Forlag, 2008. 542 s., ill.Palle Thilo: Orlogsbriggen Lougen, 18 kanoner, 1791-1802.Forlaget Falcon, 2009. 169 s., ill.Kjeld Hansen: Det tabte land. Den store fortælling om magten over det danske landskab. Gads Forlag, 2008. 847 s., ill.Anette Faye Jacobsen: Husbondret. Rettighedskulturer i Danmark 1750-1920. Museum Tusculanums Forlag, 2008. 574 s.Poul Ulrich Jensen: Byens plan. Vejles fysiske udvikling 1786-2007. Vejles Historie bd. 5. Vejle Kommune, 2007. 250 s., ill.Gerda Bonderup, Jørgen Mikkelsen og Lisbeth Skjernov (red.: „af yderste Vigtighed for det hele Borgersamfunds Tryghed“. Medicinalberetninger og deres anvendelsesmuligheder i historisk forskning. Kildeskriftselskabet, 2005. 491 s.

  20. Testing Of A Full-Scale Rotary Microfilter For The Enhanced Process For Radionuclides Removal

    International Nuclear Information System (INIS)

    Savannah River National Laboratory (SRNL) researchers are investigating and developing a rotary microfilter for solid-liquid separation applications in the Department of Energy (DOE) complex. One application involves use in the Enhanced Processes for Radionuclide Removal (EPRR) at the Savannah River Site (SRS). To assess this application, the authors performed rotary filter testing with a full-scale, 25-disk unit manufactured by SpinTek Filtration with 0.5 micron filter media manufactured by Pall Corporation. The filter includes proprietary enhancements by SRNL. The most recent enhancement is replacement of the filter's main shaft seal with a John Crane Type 28LD gas-cooled seal. The feed material was SRS Tank 8F simulated sludge blended with monosodium titanate (MST). Testing examined total insoluble solids concentrations of 0.06 wt % (126 hours of testing) and 5 wt % (82 hours of testing). The following are conclusions from this testing.

  1. Krabba : Automatisk pallkragsmontering

    OpenAIRE

    Persson, Edvin

    2012-01-01

    Företaget Goodtech Solutions AB har en prototyp av en maskin som behöver genomgå ett förbättringsarbete. Maskinen monterar automatiskt pallkragar på pall med hjälp av en robotarm. Det här arbetet fokuserar på den del av maskinen som hanterar pallkragen vid montering. Denna del kallas för krabba p.g.a. dess utseende. Målet är att genomföra förbättringsarbetet och arbetes syfte är att vara ett förbättringsunderlag för maskinen inför en framtida marknadslansering. För att montera en pallkrage lå...

  2. Optimized production technology (OPT), theory of constraints (TOC) og den dertil hørende økonomistyringstankegang 'Throughput Accounting (TPA)'

    DEFF Research Database (Denmark)

    Nielsen, Steen; Hansen, Tom Albæk

    2005-01-01

    Kombinationen af økonomistyring med forskellige andre funktionsområder, f.eks., indkøb, produktion, afsætning, adfærd etc., er et vigtigt område, og udgør efterhånden en del af det pensum, som repræsenteres i diverse lærebøger indenfor cost management accounting. OPT, TOC, TPA, samt også modeller...... danske lønsomhedsmodel, udviklet af Palle Hansen og Zakken Worre, hvor fokus også er på dækningsbidrag per knap faktor. Hvor JIT er tæt knyttet til økonomistyringstankegangen - backflush accounting - er OPT og TOC knyttet til TPA....

  3. Implementing Environmental Management Accounting: Status and Challenges

    DEFF Research Database (Denmark)

    Table of contents Preface. 1. Environmental Management Accounting: Innovation or Managerial Fad?; Pall Rikhardsson, Martin Bennett, Jan Jaap Bouma and Stefan Schaltegger. Section 1 Progress. 2. Challenges for Environmental Management Accounting; Roger L. Burritt 3. Current Trends in Environmental......: Visualizing the Policy Challenges of Environmental Management Accounting; Dick Osborn. Section 2 Exploring EMA implementation issues. 6. Environmental Performance and the Quality of Corporate Environmental Reports: The Role of Environmental Management Accounting; Marcus Wagner. 7. Environmental Risk...... Management and Environmental Management Accounting - Developing Linkages; Roger L. Burritt. 8. Using Software Systems to Support Environmental Accounting Instruments; Claus Lang, Daniel Heubach and Thoms Loew. 9. Applications of an Environmental Modelling System in the Graphics Industry and Road Haulage...

  4. TESTING OF A FULL-SCALE ROTARY MICROFILTER FOR THE ENHANCED PROCESS FOR RADIONUCLIDES REMOVAL

    Energy Technology Data Exchange (ETDEWEB)

    Herman, D; David Stefanko, D; Michael Poirier, M; Samuel Fink, S

    2009-01-01

    Savannah River National Laboratory (SRNL) researchers are investigating and developing a rotary microfilter for solid-liquid separation applications in the Department of Energy (DOE) complex. One application involves use in the Enhanced Processes for Radionuclide Removal (EPRR) at the Savannah River Site (SRS). To assess this application, the authors performed rotary filter testing with a full-scale, 25-disk unit manufactured by SpinTek Filtration with 0.5 micron filter media manufactured by Pall Corporation. The filter includes proprietary enhancements by SRNL. The most recent enhancement is replacement of the filter's main shaft seal with a John Crane Type 28LD gas-cooled seal. The feed material was SRS Tank 8F simulated sludge blended with monosodium titanate (MST). Testing examined total insoluble solids concentrations of 0.06 wt % (126 hours of testing) and 5 wt % (82 hours of testing). The following are conclusions from this testing.

  5. Epithermal Neutron Activation Analysis of the Asian Herbal Plants

    Science.gov (United States)

    Baljinnyam, N.; Jugder, B.; Norov, N.; Frontasyeva, M. V.; Ostrovnaya, T. M.; Pavlov, S. S.

    2011-06-01

    Asian medicinal herbs Chrysanthemum (Spiraea aquilegifolia Pall.) and Red Sandalwood (Pterocarpus Santalinus) are widely used in folk and Ayurvedic medicine for healing and preventing some diseases. The modern medical science has proved that the Chrysanthemum (Spiraea aquilegifolia Pall.) possesses the following functions: reducing blood press, dispelling cancer cell, coronary artery's expanding and bacteriostating and Red Sandalwood (Pterocarpus Santalinus) is recommended against headache, toothache, skin diseases, vomiting and sometimes it is taken for treatment of diabetes. Species of Chrysanthemums were collected in the north-eastern and central Mongolia, and the Red Sandalwood powder was imported from India. Samples of Chrysanthemums (branches, flowers and leaves) (0.5 g) and red sandalwood powder (0.5 g) were subjected to the multi-element instrumental neutron activation analysis using epithermal neutrons (ENAA) at the IBR-2 reactor, Frank Laboratory of Neutron Physics (FLNP) JINR, Dubna. A total of 41 elements (Na, Mg, Al, Cl, K, Ca, Sc, V, Cr, Mn, Fe, Co, Ni, Zn, As, Se, Br, Rb, Sr, Zr, Mo, Cd, Cs, Ba, La, Hf, Ta, W, Sb, Au, Hg, Ce, Nd, Sm, Eu, Tb, Dy, Yb, Th, U, Lu) were determined. For the first time such a large group of elements was determined in the herbal plants used in Mongolia. The quality control of the analytical results was provided by using certified reference material Bowen Cabbage. The results obtained are compared to the "Reference plant» data (B. Markert, 1992) and interpreted in terms of excess of such elements as Se, Cr, Ca, Fe, Ni, Mo, and rare earth elements.

  6. The extension of the combined particle-/pipe-model for the pressure drop of gasflow in packings with the tortuosity factor; Die Erweiterung des kombinierten Teilchen-/Rohr-Modells fuer den Druckabfall in gasdurchstroemten Packungen mit dem Wegfaktor

    Energy Technology Data Exchange (ETDEWEB)

    Stein, W.A.

    1998-07-01

    In an introduction the development is demonstrated for the packing columns with (a) dumped packing, (b) fluidisable packing and (c) structured packing. To calculate the pressure drop of any packing the theoretically developed particle-/pipe-model for sphere packing is extended with an adjusting parameter. For this the tortuosity factor {mu} is used. It is the quotient of the mean length of the streaming way and the shortest length of the streaming way, the height of the packing. For the dumped packing with the Raschig-ring the greatest tortuosity factor {mu}{approx}2,0 was found; for the newer packing elements the tortuosity factor diminishes from {mu}{approx}1,7 for the Pall-ring to {mu}=1,384 for Super-ring. For the fluidisable packing with the hollow sphere according to the assumptions {mu}=1,0 is valid. The smallest tortuosity factor {mu}=0,933 was found for the structured packing Mellapak. The new model is demonstrated to be universally applicable. (orig.) [Deutsch] Einleitend wird die Entwicklung skizziert bei den Packungs-Kolonnen mit (a) geschuetteter Packung, (b) wirbelfaehiger Packung und (c) geordneter Packung. Zum Erfassen des Druckabfalls beliebiger Packungen wird das theoretisch begruendete Teilchen-/Rohr-Modell fuer Kugel-Packungen erweitert mit einem Anpassungsparameter. Dazu wird der Wegfaktor {mu} herangezogen. Dies ist das Verhaeltnis der mittleren Laenge des Stroemungsweges zur kuerzest moeglichen Laenge des Stroemungsweges, der Packungshoehe. Fuer die gechuettete Packung mit dem Raschig-Ring wurde der groesste Wegfaktor {mu}{approx}2,0 ermittelt; bei den neueren Fuellkoerpern nimmt der Wegfaktor von {mu}{approx}1,7 fuer den Pall-Ring auf {mu}=1,384 fuer den Super-Ring ab. Bei der wirbelfaehigen Packung mit der Hohlkugel gilt voraussetzungsgemaess {mu}=1,0. Der Kleinstwert {mu}=0,933 ergab sich fuer die geordnete Packung Mellapak. Das neue Modell erweist sich als allgemein anwendbar. (orig.)

  7. Epithermal Neutron Activation Analysis of the Asian Herbal Plants

    International Nuclear Information System (INIS)

    Asian medicinal herbs Chrysanthemum (Spiraea aquilegifolia Pall.) and Red Sandalwood (Pterocarpus Santalinus) are widely used in folk and Ayurvedic medicine for healing and preventing some diseases. The modern medical science has proved that the Chrysanthemum (Spiraea aquilegifolia Pall.) possesses the following functions: reducing blood press, dispelling cancer cell, coronary artery's expanding and bacteriostating and Red Sandalwood (Pterocarpus Santalinus) is recommended against headache, toothache, skin diseases, vomiting and sometimes it is taken for treatment of diabetes. Species of Chrysanthemums were collected in the north-eastern and central Mongolia, and the Red Sandalwood powder was imported from India. Samples of Chrysanthemums (branches, flowers and leaves)(0.5 g) and red sandalwood powder (0.5 g) were subjected to the multi-element instrumental neutron activation analysis using epithermal neutrons (ENAA) at the IBR-2 reactor, Frank Laboratory of Neutron Physics (FLNP) JINR, Dubna. A total of 41 elements (Na, Mg, Al, Cl, K, Ca, Sc, V, Cr, Mn, Fe, Co, Ni, Zn, As, Se, Br, Rb, Sr, Zr, Mo, Cd, Cs, Ba, La, Hf, Ta, W, Sb, Au, Hg, Ce, Nd, Sm, Eu, Tb, Dy, Yb, Th, U, Lu) were determined. For the first time such a large group of elements was determined in the herbal plants used in Mongolia. The quality control of the analytical results was provided by using certified reference material Bowen Cabbage. The results obtained are compared to the ''Reference plant? data (B. Markert, 1992) and interpreted in terms of excess of such elements as Se, Cr, Ca, Fe, Ni, Mo, and rare earth elements.

  8. Clustering Analysis of Karyotype Resemblance-near Coefficient for 16 Species of Caragana Fabr.%16种锦鸡儿属植物核型似近系数聚类分析

    Institute of Scientific and Technical Information of China (English)

    宋芸; 乔永刚; 李祎; 吴玉香

    2011-01-01

    应用核型似近系数聚类分析方法研究我国16种锦鸡儿属植物的亲缘关系,并计算物种间的核型进化距离.结果表明:刺叶锦鸡儿(Caragana acanthophylla Kom.)与甘蒙锦鸡儿(C.opulens Kom.)间核型似近系数最大(0.9979),核型进化距离最小(0.0177),亲缘关系最近;青海锦鸡儿(C.chinghaiensis Liou f.)与中亚锦鸡儿[C.tragacanthoides (Pall.) Poir.]间核型似近系数最小(0.3127),核型进化距离最大(1.1625),亲缘关系最远;核型分类结果与形态学分类结果并不相符.%The genetic relationships among 16 species of Caragana were studied using karyotype resemblance-near coefficient and evolutionary distance among species was counted. The results showed that there were the biggest karyotype resemblance-near coefficient (X = 0. 9979) and the smallest evolutionary distance (De=0. 0177) between C. Acanthophylla Kom. And C. Opulens Kom. , indicating the closest relationship, and there was the minimum karyotype resemblance-near coefficient (X = 0. 3127) and the maximum evolutionary distance (De = 1. 1625) between C. Chinghaiensis Liou f. And C. Tragacanthoid.es (Pall. ) Poir. , indicating the most wide relationship. The results of clustering analysis did not accord with the phylogeny based on the morphology of these species. Results of this research have some scientific value in some study domains of this genus, such as resources utilization, taxonomy, and phylogeny.

  9. Proposing a Laser Based Beam Size Monitor for the Future Linear Collider

    International Nuclear Information System (INIS)

    Compton scattering techniques for the measurement of the transverse beam size of particle beams at future linear colliders (FLC) are proposed. At several locations of the beam delivery system (BDS) of the FLC, beam spot sizes ranging from several hundreds to a few micrometers have to be measured. This is necessary to verify beam optics, to obtain the transverse beam emittance, and to achieve the highest possible luminosity. The large demagnification of the beam in the BDS and the high beam power puts extreme conditions on any measuring device. With conventional techniques at their operational limit in FLC scenarios, new methods for the detection of the transverse beam size have to be developed. For this laser based techniques are proposed capable of measuring high power beams with sizes in the micrometer range. In this paper general aspects and critical issues of a generic device are outlined and specific solutions proposed. Plans to install a laser wire experiment at an accelerator test facility are presented

  10. 中国证券市场非线性结构的实证检验%The Empirical Test for Nonlinear Structure of China's Stock Market

    Institute of Scientific and Technical Information of China (English)

    邹裔忠

    2012-01-01

    用BDS统计量进行实证检验,找到了我国证券市场对数收益率序列存在非线性结构的证据,并且通过稳定性分析和线性过滤后的BDS统计量检验,排除了由非平稳和线性依赖产生非线性结构的可能。说明我国证券市场的非线性结构类型只能是混沌或非线性随机过程。%Through the BDS statistical test, the author discovered the evidence of the non-linear structure in the logarithmic return series of the China's stock market. And through stability analysis and the BDS statistical test after filtered linear, the author ruled out that the non-stationary and linear dependence are cause of the nonlinear structure. It is shows that the type of nonlinear structure in China's securities market only can be the chaos or nonlinear stochastic processes.

  11. AB INITIO EQUATIONS OF STATE FOR HYDROGEN (H-REOS.3) AND HELIUM (He-REOS.3) AND THEIR IMPLICATIONS FOR THE INTERIOR OF BROWN DWARFS

    Energy Technology Data Exchange (ETDEWEB)

    Becker, Andreas; Lorenzen, Winfried; Schöttler, Manuel; Redmer, Ronald [Institut für Physik, Universität Rostock, D-18051 Rostock (Germany); Fortney, Jonathan J.; Nettelmann, Nadine [Department of Astronomy and Astrophysics, University of California, Santa Cruz, CA 95064 (United States)

    2015-01-01

    We present new equations of state (EOSs) for hydrogen and helium covering a wide range of temperatures from 60 K to 10{sup 7} K and densities from 10{sup –10} g cm{sup –3} to 10{sup 3} g cm{sup –3}. They include an extended set of ab initio EOS data for the strongly correlated quantum regime with an accurate connection to data derived from other approaches for the neighboring regions. We compare linear mixing isotherms based on our EOS tables with available real mixture data. A first important astrophysical application of this new EOS data is the calculation of interior models for Jupiter and comparison with recent results. Second, mass-radius relations are calculated for Brown Dwarfs (BDs) which we compare with predictions derived from the widely used EOS of Saumon, Chabrier, and van Horn. Furthermore, we calculate interior models for typical BDs with different masses, namely, Corot-3b, Gliese-229b, and Corot-15b, and the giant planet KOI-889b. The predictions for the central pressures and densities differ by up to 10% dependent on the EOS used. Our EOS tables are made available in the supplemental material of this paper.

  12. Polymeric Biodegradable Stent Insertion in the Esophagus

    Directory of Open Access Journals (Sweden)

    Kai Yang

    2016-04-01

    Full Text Available Esophageal stent insertion has been used as a well-accepted and effective alternative to manage and improve the quality of life for patients diagnosed with esophageal diseases and disorders. Current stents are either permanent or temporary and are fabricated from either metal or plastic. The partially covered self-expanding metal stent (SEMS has a firm anchoring effect and prevent stent migration, however, the hyperplastic tissue reaction cause stent restenosis and make it difficult to remove. A fully covered SEMS and self-expanding plastic stent (SEPS reduced reactive hyperplasia but has a high migration rate. The main advantage that polymeric biodegradable stents (BDSs have over metal or plastic stents is that removal is not require and reduce the need for repeated stent insertion. But the slightly lower radial force of BDS may be its main shortcoming and a post-implant problem. Thus, strengthening support of BDS is a content of the research in the future. BDSs are often temporarily effective in esophageal stricture to relieve dysphagia. In the future, it can be expect that biodegradable drug-eluting stents (DES will be available to treat benign esophageal stricture, perforations or leaks with additional use as palliative modalities for treating malignant esophageal stricture, as the bridge to surgery or to maintain luminal patency during neoadjuvant chemoradiation.

  13. Study On Application Of Molecular Techniques (RAPD-PCR And RAMP-PCR) To Detect Mutation In Rice Breeding

    International Nuclear Information System (INIS)

    The project was carried out in 2007 with the purpose of consideration for using the two simple and inexpensive molecular techniques to estimate changes in DNA of rice mutant after gamma irradiation. Three rice cultivars: Basmati370, Tam Thom (TT1), IR64 and three gamma irradiated mutants BDS, TDS and VND 95-20 respectively, were used. Suitable DNA extraction procedure was obtained. PCR optimization was conducted on three important factors including: amount of MgCl2, DNA concentration and annealing temperature. 2.5 mM of MgCl2 for RAPD-PCR and 3.75 mM for RAMP-PCR were found the best. 40 ng DNA provided a good amplification for RAMP-PCR; this figure was 50 ng for RAPD-PCR. Annealing temperatures were determined at 36 oC for RAPD primer and at 55±3 oC for Microsatellite primer. Final results showed that, both RAPD-PCR and RAMP-PCR could detect changes in DNA of rice mutants after gamma irradiation compared to their parents. Percentage of DNA changes determined by RAPD-PCR and RAMP-PCR on Basmati370 and its mutant BDS were 11.49% and 21.2% respectively; These on TT1 and TDS were 8.98% and 15.4%; and on IR64 and VND 95-20 were 3.45% and 4.95%. (author)

  14. Executive Summary of the Workshop on Polarization and Beam Energy Measurements at the ILC

    Energy Technology Data Exchange (ETDEWEB)

    Aurand, B.; Bailey, I.; Bartels, C.; Blair, G.; Brachmann, A.; Clarke, J.; Deacon, L.; Duginov, V.; Ghalumyan, A.; Hartin, A.; Hauptman, J.; Helebrant, C.; Hesselbach, S.; Kafer, D.; List, J.; Lorenzon, W.; Lyapin, A.; Marchesini, I.; Melikian, R.; Monig, K.; Moeit, K.C.; /Bonn U. /Cockcroft Inst. Accel. Sci. Tech. /DESY /DESY, Zeuthen /Royal Holloway, U. of London /SLAC /Daresbury /Dubna, JINR /Yerevan Phys. Inst /Oxford U., JAI /Iowa State U. /Durham U., IPPP /Michigan U. /University Coll. London /Novosibirsk, IYF /Minsk, Inst. Phys. /Oregon U.

    2008-07-25

    This note summarizes the results of the 'Workshop on Polarization and Beam Energy Measurements at the ILC', held at DESY (Zeuthen) April 9-11 2008. The topics for the workshop included (1) physics requirements, (2) polarized sources and low energy polarimetry, (3) BDS polarimeters, (4) BDS energy spectrometers, and (5) physics-based measurements of beam polarization and beam energy from collider data. Discussions focused on the current ILC baseline program as described in the Reference Design Report (RDR), which includes physics runs at beam energies between 100 and 250 GeV, as well as calibration runs on the Z-pole. Electron polarization of P{sub e{sup -}} {approx}> 80% and positron polarization of P{sub e{sup +}} {approx}> 30% are part of the baseline configuration of the machine. Energy and polarization measurements for ILC options beyond the baseline, including Z-pole running and the 1 TeV energy upgrade, were also discussed.

  15. THE FIRST ULTRA-COOL BROWN DWARF DISCOVERED BY THE WIDE-FIELD INFRARED SURVEY EXPLORER

    International Nuclear Information System (INIS)

    We report the discovery of the first new ultra-cool brown dwarf (BDs) found with the Wide-field Infrared Survey Explorer (WISE). The object's preliminary designation is WISEPC J045853.90+643451.9. Follow-up spectroscopy with the LUCIFER instrument on the Large Binocular Telescope indicates that it is a very late-type T dwarf with a spectral type approximately equal to T9. Fits to an IRTF/SpeX 0.8-2.5 μm spectrum to the model atmospheres of Marley and Saumon indicate an effective temperature of approximately 600 K as well as the presence of vertical mixing in its atmosphere. The new BD is easily detected by WISE, with a signal-to-noise ratio of ∼36 at 4.6 μm. Current estimates place it at a distance of 6-10 pc. This object represents the first in what will likely be hundreds of nearby BDs found by WISE that will be suitable for follow-up observations, including those with the James Webb Space Telescope. One of the two primary scientific goals of the WISE mission is to find the coolest, closest stars to our Sun; the discovery of this new BD proves that WISE is capable of fulfilling this objective.

  16. The First Ultra-cool Brown Dwarf Discovered by the Wide-field Infrared Survey Explorer

    Science.gov (United States)

    Mainzer, A.; Cushing, Michael C.; Skrutskie, M.; Gelino, C. R.; Kirkpatrick, J. Davy; Jarrett, T.; Masci, F.; Marley, Mark S.; Saumon, D.; Wright, E.; Beaton, R.; Dietrich, M.; Eisenhardt, P.; Garnavich, P.; Kuhn, O.; Leisawitz, D.; Marsh, K.; McLean, I.; Padgett, D.; Rueff, K.

    2011-01-01

    We report the discovery of the first new ultra-cool brown dwarf (BDs) found with the Wide-field Infrared Survey Explorer (WISE). The object's preliminary designation is WISEPC J045853.90+643451.9. Follow-up spectroscopy with the LUCIFER instrument on the Large Binocular Telescope indicates that it is a very late-type T dwarf with a spectral type approximately equal to T9. Fits to an IRTF/SpeX 0.8-2.5 μm spectrum to the model atmospheres of Marley and Saumon indicate an effective temperature of approximately 600 K as well as the presence of vertical mixing in its atmosphere. The new BD is easily detected by WISE, with a signal-to-noise ratio of ~36 at 4.6 μm. Current estimates place it at a distance of 6-10 pc. This object represents the first in what will likely be hundreds of nearby BDs found by WISE that will be suitable for follow-up observations, including those with the James Webb Space Telescope. One of the two primary scientific goals of the WISE mission is to find the coolest, closest stars to our Sun; the discovery of this new BD proves that WISE is capable of fulfilling this objective.

  17. Preconceptional Iron Intake and Gestational Diabetes Mellitus

    Science.gov (United States)

    Darling, Anne Marie; Mitchell, Allen A.; Werler, Martha M.

    2016-01-01

    Our objective was to assess the impact of preconceptional heme and non-heme iron on gestational diabetes mellitius (GDM) in the Boston University Slone Epidemiology Birth Defects Study (BDS). This retrospective cohort analysis included 7229 participants enrolled in the BDS between 1998 and 2008 who gave birth to non-malformed infants and were free of pre-existing diabetes. All data were collected through structured interviews conducted within 6 months of delivery. Calorie-adjusted and multivariable odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using logistic regression models. Preconceptional dietary heme iron was modestly associated with an elevated risk of GDM among those (multivariable OR comparing the fifth quintile to the first: 1.55; 95% CI 0.98, 2.46). Conversely, preconceptional dietary non-heme iron was associated with a decreased risk of GDM among those in the fifth quintile of intake compared to the first (multivariable OR: 0.48; 95% CI 0.28, 0.81). Women who consumed supplemental iron during preconception also had a decreased risk of GDM (multivariable OR: 0.78; 95% CI 0.60, 1.02). In conclusion, our data support a positive association between preconceptional heme iron intake and GDM and an inverse association between preconceptional non-heme iron intake from foods and preconceptional intake from supplements. PMID:27231921

  18. Noise Reduction Analysis of Radar Rainfall Using Chaotic Dynamics and Filtering Techniques

    Directory of Open Access Journals (Sweden)

    Soojun Kim

    2014-01-01

    Full Text Available The aim of this study is to evaluate the filtering techniques which can remove the noise involved in the time series. For this, Logistic series which is chaotic series and radar rainfall series are used for the evaluation of low-pass filter (LF and Kalman filter (KF. The noise is added to Logistic series by considering noise level and the noise added series is filtered by LF and KF for the noise reduction. The analysis for the evaluation of LF and KF techniques is performed by the correlation coefficient, standard error, the attractor, and the BDS statistic from chaos theory. The analysis result for Logistic series clearly showed that KF is better tool than LF for removing the noise. Also, we used the radar rainfall series for evaluating the noise reduction capabilities of LF and KF. In this case, it was difficult to distinguish which filtering technique is better way for noise reduction when the typical statistics such as correlation coefficient and standard error were used. However, when the attractor and the BDS statistic were used for evaluating LF and KF, we could clearly identify that KF is better than LF.

  19. Selection of mesophilic microorganisms with biodesulfuration capacity

    International Nuclear Information System (INIS)

    The development of bio desulfurization (BDS) processes for hydrocarbons requires fast and reliable methods for the screening of microorganisms. This work shows the results of the screening process for indigenous Colombian strains with a BDS potential capacity. The main criteria for the screening were the qualitative and quantitative determination of 2-hydroxybiphenyl (2-HBP) as the typical metabolite of the 4S specific pathway. Microorganisms were cultured by two methodologies, A and B, using DBT as the model compound. The quantitative determination of metabolites was made by HPLC. Thirteen strains were evaluated, including the strain Rhodococcus rhodocrous IGTS8, by methods A and B. In method A, the inoculum was exposed to DBT since the beginning of the culture. Method B, employed two stages: (i) Growth period under limiting sulfur conditions, (ii) Transforming period, in which the pre-grown inoculum was exposed to the organic sulfur substrate. The culture of mesophilic microorganisms isolated by method B, served to find a mechanism for the organic sulfur metabolism, and the evaluation of the sulfur removal capability of five indigenous strains. In the cultures of these strains, 2- hydroxybiphenyl (2-HBP) was detected as a byproduct of DBT metabolism, both qualitatively and quantitatively

  20. Micropropagation of onion (Allium cepa L.) from immature inflorescences.

    Science.gov (United States)

    Marinangeli, Pablo

    2013-01-01

    In vitro plant production by direct organogenesis from immature flower heads is an ideal approach for clonal propagation of onions (Allium cepa L.). This technique ensures genetic stability, high propagation rate, and maintains donor plant of explants with an advantage over other means of in vitro regeneration. Onion micropropagation is usually applied in breeding programs, maintenance, and multiplication of cytoplasmic-male sterile lines for hybrid production, germplasm conservation, and as a tool for the application of other biotechnologies. For in vitro culture, mature onion bulbs are induced to reproductive phase by vernalization and forced to inflorescence initiation. Immature umbels are dissected from bulbs or cut directly when they appear from the pseudostem among the leaves. Disinfected inflorescences are cultivated in BDS basal medium supplemented with 30 g/L sucrose, 0.1 mg/L naphthalene acetic acid, 1 mg/L N (6)-benzyladenine, and 8 g/L agar, pH 5.5, under 16 h photoperiod white fluorescent light (PPD: 50-70 μmol/m(2)s) for 35 days. The regenerated shoot clumps are divided and subculture under the same conditions. For bulbification phase, the individual shoots are cultured in BDS basal medium containing 90 g/L sucrose, without plant growth regulators, pH 5.5, under 16 h photoperiod. Microbulbs can be directly cultivated ex vitro without acclimation. PMID:23179710

  1. Hints for new sources of flavour violation in meson mixing

    CERN Document Server

    Blanke, Monika

    2016-01-01

    The recent results by the Fermilab Lattice and MILC collaborations on the hadronic matrix elements entering $B_{d,s}-\\bar B_{d,s}$ mixing show a significant tension of the measured values of the mass differences $\\Delta M_{d,s}$ with their SM predictions. We review the implications of these results in the context of Constrained Minimal Flavour Violation models. In these models, the CKM elements $\\gamma$ and $|V_{ub}|/|V_{cb}|$ can be determined from $B_{d,s}-\\bar B_{d,s}$ mixing observables, yielding a prediction for $\\gamma$ below its tree-level value. Determining subsequently $|V_{cb}|$ from the measured value of either $\\Delta M_s$ or $\\varepsilon_K$ gives inconsistent results, with the tension being smallest in the Standard Model limit. This tension can be resolved if the flavour universality of new contributions to $\\Delta F = 2$ observables is broken. We briefly discuss the case of $U(2)^3$ flavour models as an illustrative example.

  2. Cognitive changes after carotid artery stenting

    Energy Technology Data Exchange (ETDEWEB)

    Grunwald, I.Q.; Politi, M.; Struffert, T.; Krick, C.; Backens, M. [University of the Saarland, Department for Diagnostic and Interventional Neuroradiology, Homburg (Germany); Supprian, T.; Falkai, P.; Reith, W. [University of the Saarland, Clinic for Psychiatry and Psychotherapy, Homburg (Germany)

    2006-05-15

    We aimed to test changes in cognitive performance after carotid artery stenting (CAS). Ten patients were neuropsychologically tested at least 24 h before and 48 h after CAS. To diminish thromboembolic events, we used a proximal protection device. The following neuropsychological tests were selected: The Mini Mental State Examination (MMSE), symbol digit test and subtests of the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) battery (verbal fluency, constructional practice, word list memory and delayed recall). Affective state was determined by the Beck Depression Score (BDS). No patient suffered from depression (BDS <1) or dementia (MMSE 29.9{+-}1.5). Nine of the ten patients (P=0.12) showed increased speed in the Number Connection Test (NCT) (corresponding to trail making test). Most patients showed better or similar results concerning delayed recall (P=0.31). No change was observed in the symbol digit test, word list memory, verbal fluency or constructional practice. Better results concerning NCT and delayed recall after carotid stenting might be due to improved brain perfusion. After CAS, cognitive and memory performance seem to improve. Further studies with different time intervals and more refined testing, as well as perfusion-weighted imaging, are needed. (orig.)

  3. High Breakdown Strength, Multilayer Ceramics for Compact Pulsed Power Applications

    Energy Technology Data Exchange (ETDEWEB)

    Gilmore, B.; Huebner, W.; Krogh, M.L.; Lundstrom, J.M.; Pate, R.C.; Rinehart, L.F.; Schultz, B.C.; Zhang, S.C.

    1999-07-20

    Advanced ceramics are being developed for use in large area, high voltage devices in order to achieve high specific energy densities (>10 6 J/m 3 ) and physical size reduction. Initial materials based on slip cast TiO2 exhibited a high bulk breakdown strength (BDS >300 kV/cm) and high permittivity with low dispersion (e�100). However, strong area and thickness dependencies were noted. To increase the BDS, multilayer dielectric compositions are being developed based on glass/TiO2 composites. The addition of glass increases the density (�99.8% theoretical), forms a continuous grain boundary phase, and also allows the use of high temperature processes to change the physical shape of the dielectric. The permittivity can also be manipulated since the volume fraction and connectivity of the glassy phase can be readily shifted. Results from this study on bulk breakdown of TiO2 multilayer structures with an area of 2cm 2 and 0.1cm thickness have measured 650 kV/cm. Furthermore, a strong dependence of breakdown strength and permittivity has been observed and correlated with microstructure and the glass composition. This paper presents the interactive effects of manipulation of these variables.

  4. Constraints on the binary properties of mid- to late T dwarfs from Hubble space telescope WFC3 observations

    Energy Technology Data Exchange (ETDEWEB)

    Aberasturi, M.; Solano, E. [Centro de Astrobiología (INTA-CSIC), Departamento de Astrofísica, P.O. Box 78, E-28691 Villanueva de la Cañada, Madrid (Spain); Burgasser, A. J. [Center for Astrophysics and Space Science, University of California San Diego, La Jolla, CA 92093 (United States); Mora, A. [ESA–ESAC, Gaia SOC. P.O. Box 78, E-28691 Villanueva de la Cañada, Madrid (Spain); Martín, E. L. [Centro de Astrobiología (INTA-CSIC), Departamento de Astrofísica. Carretera de Ajalvir km 4, E-28550 Torrejín de Ardoz, Madrid (Spain); Reid, I. N. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Looper, D. [Institute for Astronomy, University of Hawaii, 2680 Woodlawn Drive, Honolulu, HI 96822 (United States)

    2014-12-01

    We used Hubble Space Telescope/Wide Field Camera 3 (WFC3) observations of a sample of 26 nearby (≤20 pc) mid- to late T dwarfs to search for cooler companions and measure the multiplicity statistics of brown dwarfs (BDs). Tightly separated companions were searched for using a double point-spread-function-fitting algorithm. We also compared our detection limits based on simulations to other prior T5+ BD binary programs. No new wide or tight companions were identified, which is consistent with the number of known T5+ binary systems and the resolution limits of WFC3. We use our results to add new constraints to the binary fraction (BF) of T-type BDs. Modeling selection effects and adopting previously derived separation and mass ratio distributions, we find an upper limit total BF of <16% and <25% assuming power law and flat mass ratio distributions, respectively, which are consistent with previous results. We also characterize a handful of targets around the L/T transition.

  5. Preconceptional Iron Intake and Gestational Diabetes Mellitus.

    Science.gov (United States)

    Darling, Anne Marie; Mitchell, Allen A; Werler, Martha M

    2016-01-01

    Our objective was to assess the impact of preconceptional heme and non-heme iron on gestational diabetes mellitius (GDM) in the Boston University Slone Epidemiology Birth Defects Study (BDS). This retrospective cohort analysis included 7229 participants enrolled in the BDS between 1998 and 2008 who gave birth to non-malformed infants and were free of pre-existing diabetes. All data were collected through structured interviews conducted within 6 months of delivery. Calorie-adjusted and multivariable odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using logistic regression models. Preconceptional dietary heme iron was modestly associated with an elevated risk of GDM among those (multivariable OR comparing the fifth quintile to the first: 1.55; 95% CI 0.98, 2.46). Conversely, preconceptional dietary non-heme iron was associated with a decreased risk of GDM among those in the fifth quintile of intake compared to the first (multivariable OR: 0.48; 95% CI 0.28, 0.81). Women who consumed supplemental iron during preconception also had a decreased risk of GDM (multivariable OR: 0.78; 95% CI 0.60, 1.02). In conclusion, our data support a positive association between preconceptional heme iron intake and GDM and an inverse association between preconceptional non-heme iron intake from foods and preconceptional intake from supplements. PMID:27231921

  6. IRAS 16253-2429: the First Proto-Brown Dwarf Binary Candidate Identified through Dynamics of Jets

    CERN Document Server

    Hsieh, Tien-Hao; Belloche, Arnaud; Wyrowski, Friedrich

    2016-01-01

    The formation mechanism of brown dwarfs (BDs) is one of the long-standing problems in star formation because the typical Jeans mass in molecular clouds is too large to form these substellar objects. To answer this question, it is crucial to study a BD at the embedded phase. IRAS 16253-2429 is classified as a very low luminosity object (VeLLO) with internal luminosity 0.1 Lsun. VeLLOs are believed to be very low-mass protostars or even proto-BDs. We observed the jet/outflow driven by IRAS 16253-2429 in CO (2-1), (6-5), and (7-6) using the IRAM 30 m and APEX telescopes and the SMA in order to study its dynamical features and physical properties. Our SMA map reveals two protostellar jets, indicating the existence of a proto-binary system as implied by the precessing jet detected in H2 emission. We detect a wiggling pattern in the position-velocity diagrams along the jet axes, which is likely due to the binary orbital motion. Based on this, we derive the current mass of the binary as ~0.032 Msun. Given the low en...

  7. The influence of different types of satellite exiting in system RAIM performance in BeiDou Satellite Navigation System

    Science.gov (United States)

    Wang, Shi-tai; Peng, Jun-huan

    2015-12-01

    The space constellation of BeiDou Navigation Satellite System(BDS)has three main components, Geostationary Earth Orbits (GEOs), Medium Earth Orbits (MEOs) and Inclined Geosynchronous Satellite Orbits(IGSOs).This paper selected 6 satellite respectively in three types to simulate their exiting service, and used the statistical methods to assess receiver autonomous integrity monitoring RAIM availability and fault detection FD capability of BeiDou14 Phase with 14 satellites under the circumstances. This paper assessed RAIM availability performance from satellites and constellation geometry configuration by the number of visible satellites (NVS, NVS>~5) and position dilution of precision (PDOP, PDOPMDE). The analyses of simulation results testify that the exiting of single MEO or IGSO satellite have no obvious effect on RAIM availability and error detection ability. However GEO satellite's exiting can make the number of points in where the constellation geometry is not available and maximum minimum detectable deviation and maximum minimum detectable influence significantly increase. Relative to other two satellites, GEO satellites' health have a significant impact on the RAIM performance of BDS.

  8. Cognitive changes after carotid artery stenting

    International Nuclear Information System (INIS)

    We aimed to test changes in cognitive performance after carotid artery stenting (CAS). Ten patients were neuropsychologically tested at least 24 h before and 48 h after CAS. To diminish thromboembolic events, we used a proximal protection device. The following neuropsychological tests were selected: The Mini Mental State Examination (MMSE), symbol digit test and subtests of the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) battery (verbal fluency, constructional practice, word list memory and delayed recall). Affective state was determined by the Beck Depression Score (BDS). No patient suffered from depression (BDS <1) or dementia (MMSE 29.9±1.5). Nine of the ten patients (P=0.12) showed increased speed in the Number Connection Test (NCT) (corresponding to trail making test). Most patients showed better or similar results concerning delayed recall (P=0.31). No change was observed in the symbol digit test, word list memory, verbal fluency or constructional practice. Better results concerning NCT and delayed recall after carotid stenting might be due to improved brain perfusion. After CAS, cognitive and memory performance seem to improve. Further studies with different time intervals and more refined testing, as well as perfusion-weighted imaging, are needed. (orig.)

  9. High level expression of human epithelial β-defensins (hBD-1, 2 and 3 in papillomavirus induced lesions

    Directory of Open Access Journals (Sweden)

    Chong Kong T

    2006-09-01

    Full Text Available Abstract Background Epithelial defensins including human β-defensins (hBDs and α-defensins (HDs are antimicrobial peptides that play important roles in the mucosal defense system. However, the role of defensins in papillomavirus induced epithelial lesions is unknown. Results Papilloma tissues were prospectively collected from 15 patients with recurrent respiratory papillomatosis (RRP and analyzed for defensins and chemokine IL-8 expression by quantitative, reverse-transcriptase polymerase chain reaction (RT-PCR assays. HBD-1, -2 and -3 mRNAs were detectable in papilloma samples from all RRP patients and the levels were higher than in normal oral mucosal tissues from healthy individuals. Immunohistochemical analysis showed that both hBD-1 and 2 were localized in the upper epithelial layers of papilloma tissues. Expression of hBD-2 and hBD-3 appeared to be correlated as indicated by scatter plot analysis (r = 0.837, p Conclusion Human β-defensins are upregulated in respiratory papillomas. This novel finding suggests that hBDs might contribute to innate and adaptive immune responses targeted against papillomavirus-induced epithelial lesions.

  10. Genetic analysis of benzothiophene biodesulfurization pathway of Gordonia terrae strain C-6.

    Directory of Open Access Journals (Sweden)

    Wei Wang

    Full Text Available Sulfur can be removed from benzothiophene (BT by some bacteria without breaking carbon-carbon bonds. However, a clear mechanism for BT desulfurization and its genetic components have not been reported in literatures so far. In this study, we used comparative transcriptomics to study differential expression of genes in Gordonia terrae C-6 cultured with BT or sodium sulfate as the sole source of sulfur. We found that 135 genes were up-regulated with BT relative to sodium sulfate as the sole sulfur source. Many of these genes encode flavin-dependent monooxygenases, alkane sulfonate monooxygenases and desulfinase, which perform similar functions to those involved in the 4S pathway of dibenzothiophene (DBT biodesulfurization. Three of the genes were found to be located in the same operon, designated bdsABC. Cell extracts of pET28a-bdsABC transfected E. coli Rosetta (DE3 converted BT to a phenolic compound, identified as o-hydroxystyrene. These results advance our understanding of enzymes involved in the BT biodesulfurization pathway.

  11. Constraints on the binary properties of mid- to late T dwarfs from Hubble space telescope WFC3 observations

    International Nuclear Information System (INIS)

    We used Hubble Space Telescope/Wide Field Camera 3 (WFC3) observations of a sample of 26 nearby (≤20 pc) mid- to late T dwarfs to search for cooler companions and measure the multiplicity statistics of brown dwarfs (BDs). Tightly separated companions were searched for using a double point-spread-function-fitting algorithm. We also compared our detection limits based on simulations to other prior T5+ BD binary programs. No new wide or tight companions were identified, which is consistent with the number of known T5+ binary systems and the resolution limits of WFC3. We use our results to add new constraints to the binary fraction (BF) of T-type BDs. Modeling selection effects and adopting previously derived separation and mass ratio distributions, we find an upper limit total BF of <16% and <25% assuming power law and flat mass ratio distributions, respectively, which are consistent with previous results. We also characterize a handful of targets around the L/T transition.

  12. AB INITIO EQUATIONS OF STATE FOR HYDROGEN (H-REOS.3) AND HELIUM (He-REOS.3) AND THEIR IMPLICATIONS FOR THE INTERIOR OF BROWN DWARFS

    International Nuclear Information System (INIS)

    We present new equations of state (EOSs) for hydrogen and helium covering a wide range of temperatures from 60 K to 107 K and densities from 10–10 g cm–3 to 103 g cm–3. They include an extended set of ab initio EOS data for the strongly correlated quantum regime with an accurate connection to data derived from other approaches for the neighboring regions. We compare linear mixing isotherms based on our EOS tables with available real mixture data. A first important astrophysical application of this new EOS data is the calculation of interior models for Jupiter and comparison with recent results. Second, mass-radius relations are calculated for Brown Dwarfs (BDs) which we compare with predictions derived from the widely used EOS of Saumon, Chabrier, and van Horn. Furthermore, we calculate interior models for typical BDs with different masses, namely, Corot-3b, Gliese-229b, and Corot-15b, and the giant planet KOI-889b. The predictions for the central pressures and densities differ by up to 10% dependent on the EOS used. Our EOS tables are made available in the supplemental material of this paper

  13. Management of bipolar disorders in women by nonpharmacological methods.

    Science.gov (United States)

    Naik, Sujit Kumar

    2015-07-01

    Several reasons justify the need for nonpharmacological interventions for bipolar disorder (BD) in women. This review focuses on psychosocial therapies for BDs in women. The research evidence for a wide range of psychosocial interventions for the management of BDs in women has been presented. All the interventions have some common components like targeting disease management, information regarding illness, and coping skills. There also are distinctive features like cognitive restructuring and self-rated mood charts in cognitive behavior therapy, regulation of sleep/wake cycles and daily routines in interpersonal sleep regulation therapy, and communication skill training in family treatments. Many psychosocial interventions hold promise as adjunctive therapies for bipolar patients. In India, there is a considerable dearth of literature in this area due lack of skilled staff for psychosocial interventions. Future trials need to: Clarify which populations are most likely to benefit from which strategies; identify putative mechanisms of action; systematically evaluate costs, benefits, and generalizability of effects, and record adverse effects. PMID:26330644

  14. BeiDou phase bias estimation and its application in precise point positioning with triple-frequency observable

    Science.gov (United States)

    Gu, Shengfeng; Lou, Yidong; Shi, Chuang; Liu, Jingnan

    2015-10-01

    At present, the BeiDou system (BDS) enables the practical application of triple-frequency observable in the Asia-Pacific region, of many possible benefits from the additional signal; this study focuses on exploiting the contribution of zero difference (ZD) ambiguity resolution (AR) to the precise point positioning (PPP). A general modeling strategy for multi-frequency PPP AR is presented, in which, the least squares ambiguity decorrelation adjustment (LAMBDA) method is employed in ambiguity fixing based on the full variance-covariance ambiguity matrix generated from the raw data processing model. Because of the reliable fixing of BDS L1 ambiguity faces more difficulty, the LAMBDA method with partial ambiguity fixing is proposed to enable the independent and instantaneous resolution of extra wide-lane (EWL) and wide-lane (WL). This mechanism of sequential ambiguity fixing is demonstrated for resolving ZD satellite phase bias and performing triple-frequency PPP AR with two reference station networks with a typical baseline of up to 400 and 800 km, respectively. Tests show that about of the EWL and WL phase bias of BDS has a consistency of better than 0.1 cycle, and this value decreases to 80 % for L1 phase bias for Experiment I, while all the solutions of Experiment II have a similar RMS of about 0.12 cycles. In addition, the repeatability of the daily mean phase bias agree to 0.093 cycles and 0.095 cycles for EWL and WL on average, which is much smaller than 0.20 cycles of L1. To assess the improvement of fixed PPP brought by applying the third frequency signal as well as the above phase bias, various ambiguity fixing strategy are considered in the numerical demonstration. It is shown that the impact of the additional signal is almost negligible when only float solution involved. It is also shown that by fixing EWL and WL together, as opposed to the single ambiguity fixing, will leads to an improvement in PPP accuracy by about on average. Attributed to the efficient

  15. The VLT/NaCo large program to probe the occurrence of exoplanets and brown dwarfs at wide orbits . III. The frequency of brown dwarfs and giant planets as companions to solar-type stars

    Science.gov (United States)

    Reggiani, M.; Meyer, M. R.; Chauvin, G.; Vigan, A.; Quanz, S. P.; Biller, B.; Bonavita, M.; Desidera, S.; Delorme, P.; Hagelberg, J.; Maire, A.-L.; Boccaletti, A.; Beuzit, J.-L.; Buenzli, E.; Carson, J.; Covino, E.; Feldt, M.; Girard, J.; Gratton, R.; Henning, T.; Kasper, M.; Lagrange, A.-M.; Mesa, D.; Messina, S.; Montagnier, G.; Mordasini, C.; Mouillet, D.; Schlieder, J. E.; Segransan, D.; Thalmann, C.; Zurlo, A.

    2016-02-01

    Context. In recent years there have been many attempts to characterize the occurrence and distribution of stellar, brown dwarf (BD), and planetary-mass companions to solar-type stars with the aim of constraining formation mechanisms. From radial velocity observations a dearth of companions with masses between 10-40 MJupiter has been noticed at close separations, suggesting the possibility of a distinct formation mechanism for objects above and below this range. Aims: We present a model for the substellar companion mass function (CMF). This model consists of the superposition of the planet and BD companion mass distributions, assuming that we can extrapolate the radial velocity measured CMF for planets to larger separations and the stellar companion mass-ratio distribution over all separations into the BD mass regime. By using both the results of the VLT/NaCo large program (NaCo-LP) and the complementary archive datasets, which probe the occurrence of planets and BDs on wide orbits around solar-type stars, we place some constraints on the planet and BD distributions. Methods: We developed a Monte Carlo simulation tool to predict the outcome of a given survey, depending on the shape of the orbital parameter distributions (mass, semimajor axis, eccentricity, and inclination). Comparing the predictions with the results of the observations, we calculate the likelihood of different models and which models can be ruled out. Results: Current observations are consistent with the proposed model for the CMF, as long as a sufficiently small outer truncation radius (≲100 AU) is introduced for the planet separation distribution. Some regions of parameter space can be excluded by the observations. Conclusions: We conclude that the results of the direct imaging surveys searching for substellar companions around Sun-like stars are consistent with a combined substellar mass spectrum of planets and BDs. This mass distribution has a minimum between 10 and 50 MJupiter, in agreement

  16. Edge and core dynamics in harness

    International Nuclear Information System (INIS)

    Resistive kink oscillations in tokamak plasmas are usually treated as core localized events, yet there there are several mechanisms by which they may interact with the edge dynamics. This suggests that we may regulate edge oscillatory behaviour, or ELMs, by harnessing the natural or contrived sawtooth period and amplitude. In this work I investigate core-edge oscillatory entrainment through direct propagation of heat pulses, inductive coupling, and global higher order resonance effects. In the core of auxiliary heated tokamak plasmas the ineluctable rhythm of slow buildup and rapid conversion of potential energy governs electron and heat radial transport. The growth phase of the sawtooth is accompanied by significant reconnection, then during the collapse the temperature and density in the core fall dramatically. There is evidence from experiments in reversed field pinch devices that ensuing energy fluxes can affect flow shear and confinement at the edge. The basis for this study is the dynamical (BDS) model for edge plasma behavior that was derived from electrostatic resistive MHD equations. The BDS model reflects the major qualitative features of edge dynamics that have been observed, such as L-H transitions and associated ELMs, hysteresis, and spontaneous reversal of poloidal shear flow. Under poorly dissipative conditions the transient behavior of the model can exhibit period-doubling, blue-sky, homoclinic, and other exotic bifurcations. Thus we might ask questions such as: Is it possible to mode-lock the edge dynamics to the core sawteeth? Can we induce, or prevent, a change in direction of shear flow? What about MHD effects? Is core-edge communication one way or is there some feedback? In the simplest prototype for coupled core-edge dynamics I model the sawtooth crash as a periodic power input to the edge potential energy reservoir. This is effected by coupling the BDS model to the dynamical system u = u(1 - u2 - x2) - ωsx, x = x(1-u2 -x2) + ωsu, which has

  17. Investigation into biological nutrient removal from wastewater

    OpenAIRE

    Vabolienė, Giedrė; Matuzevičius, Algirdas Bronislovas

    2005-01-01

    Siekiant išvengti eutrofizacijos vandens telkiniuose, išleidžiant valytas nuotekas į uždarus ar mažai pratekančius vandens telkinius bei pakartotinai jas panaudojant kaip technologinį vandenį, būtina šalinti azotą ir fosforą. Viena iš naujausių azoto ir fosforo šalinimo technologijų – „BioBalance“ technologija pritaikyta Utenos miesto nuotekų valymo įrenginiuose. Šalinant fosforą biologiniu būdu didelės įtakos turi valomų nuotekų sudėtis, ypač svarbu žinoti BDS7/BP santykį nuotekose po mechan...

  18. Chaotic Properties of the Philippine Stock Exchange Index Returns

    Directory of Open Access Journals (Sweden)

    Jo-Hui Chen

    2015-03-01

    Full Text Available This study found evidences of chaos in the Philippine Stock Exchange Index (PSEi returns using three tests of chaotic behavior. The BDS test found that PSEi returns and ARMA residuals are not stochastic processes. With regards to the efficient market hypothesis (EMH, this paper cannot conclude the iid properties of GARCH residuals, except for the period of the Subprime Mortgage Crisis. The rescaled range (R/S analysis showed that most Hurst exponents of the PSEi returns, ARMA and GARCH residuals have chaotic tendencies and have trend-reinforcing series, but showed anti-persistence during crisis. Furthermore, the correlation dimension analyses supplemented the first two initial tests and showed that the correlation dimension does not converge to a stable value as the embedding dimension increases. Both values increased in relation with each other, further confirming that PSEi returns, ARMA and GARCH residuals are consistent with chaos.

  19. BFKL Pomeron and Bern-Dixon-Smirnov amplitudes in N=4 SUSY

    Energy Technology Data Exchange (ETDEWEB)

    Lipatov, L.N. [Petersburg Nuclear Physics Institute (Russian Federation)]|[Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik

    2008-10-15

    We review the theoretical approaches for investigations of the high energy hadron-hadron scattering in the Regge kinematics. It is demonstrated, that the gluon in QCD is reggeized and the Pomeron is a composite state of the reggeized gluons. Remarkable properties of the BFKL equation for the Pomeron wave function in QCD and supersymmetric gauge theories are outlined. Due to the AdS/CFT correspondence the BFKL Pomeron is equivalent to the reggeized graviton in the extended N=4 SUSY. The properties of the maximal transcendentality and integrability are realized in this model. The BDS multi-gluon scattering amplitudes are investigated in the Regge limit. They do not contain the Mandelstam cuts and are not valid beyond one loop. It is shown, that the hamiltonian for these composite states coincides with the hamiltonian of an integrable open Heisenberg spin chain. (orig.)

  20. THE ROLE OF STUDENT CHARACTERISTICS IN PROBLEM BASED LEARNING

    Directory of Open Access Journals (Sweden)

    Mia Damiyanti

    2006-04-01

    Full Text Available To reach the effectiveness of study, it is recommended to work on active learning method. The learning activity must be done with emphasis on the students’ characteristics. The characteristic means internal factors (cognitive entry behavior and affective entry characteristics, which are considered important as solving problems. The previous studies have shown that there is a correlation between achievement test and students’ characteristic entry behavior. At the beginning of the academic year of 2003, Faculty of Dentistry, University of Indonesia started active learning with PBL curriculum for the BDS degree. From a study about the correlation between the achievement and students’ entry behavior (previous knowledge, self concept, attitude, and anxiety during attending the test the study showed that characteristic entry behavior contributes to the student’s achievement test. The results supported the previous study.

  1. Determination of related substances in lisinopril and amlodipine tablets by HPLC

    Institute of Scientific and Technical Information of China (English)

    Dao-Rui Yu; Gui-Fang Yang; Wen-Li Xiao; Jun Wang; Qi-Bing Liu

    2016-01-01

    Objective:To establish an HPLC method for determining the related substances in lisinopril and amlodipine tablets.Methods:An Inertsil Thermo BDS HYPERSIL C18 (4.6 mmí250 mm, 5 μm) column was used with the Acetonitrile-water-phosphoric acid (10:90:0.1) as mobile phase A and Acetonitrile-water-phosphoric acid (90:10:0.1) as mobile phase B by gradient elution at the detection wavelength of 215 nm. The flow rate was 1.0 mL/min and the column temperature was 30℃.Results: The separation of the impurity peak and peak was good. Besides, all the impurities could be detected effectively.Conclusions:The method is sensitive, accurate and selective. It is suitable for control the related substances in lisinopril and Amlodipine tablets.

  2. Effect of annealing time, weight pressure and cobalt doping on the electrical and magnetic behavior of barium titanate

    Science.gov (United States)

    Samuvel, K.; Ramachandran, K.

    2016-05-01

    BaTi0.5CO0.5O3 (BTCO) nanoparticles were prepared by the solid state reaction technique using different starting materials and the microstructure examined by XRD, FESEM, BDS and VSM. X-ray diffraction and electron diffraction patterns showed that the nanoparticles were the tetragonal BTCO phase. The BTCO nanoparticles prepared from the starting materials of as prepared titanium-oxide, Cobalt -oxide and barium carbonate have spherical grain morphology, an average size of 65 nm and a fairly narrow size distribution. The nano-scale presence and the formation of the tetragonal perovskite phase as well as the crystallinity were detected using the mentioned techniques. Dielectric properties of the samples were measured at different frequencies. Broadband dielectric spectroscopy is applied to investigate the electrical properties of disordered perovskite-like ceramics in a wide temperature range. The doped BTCO samples exhibited low loss factor at 1 kHz and 1 MHz frequencies respectively.

  3. Optimization of nicotinamide and riboflavin in the biodesulfurization of dibenzothiophene using response surface methodology

    Directory of Open Access Journals (Sweden)

    Hossein Saber

    2013-01-01

    Full Text Available Introduction: Dibenzothiophene (DBT is a sulfuric compound and resistant to Hydrodesulfurization process.Rhodococcuserythropolis R1, a previously isolated bacterial strain, is capable to bioconversion of DBT to 2-hydroxybiphenyl (2-HBP.Materials and methods: The effect of nicotinamide (precursor of NAD and riboflavin (precursor of FMN on DBT biodesulfurization and growth rate by this strain was studied using Gibbs assay and turbidimeteric assay respectively. The level of cofactor precursors were optimized using response surface methodology (RSM. Results: Analyses showed that both nicotinamide and riboflavin were statistically significant and could enhance the biodesulfurization rate of DBT by induction of dsz operon. The optimum level of nicotinamide and riboflavin was obtained at 10.67 mM and 34.2 µM respectively. Discussion and conclusion: In spite of increasing in BDS, the addition of these cofactor precursors led to decreased growth rate and biomass production due to limitated effect of produced 2-HBP.

  4. Desarrollo y evaluación de una aplicación Web estandarizada para el almacenamiento e intercambio de Historiales Clínicos Electrónicos (HCEs) en oftalmología: TeleOftalWeb

    OpenAIRE

    Torre Díez, Isabel de la

    2010-01-01

    El objetivo de la presente Tesis es el desarrollo, puesta en marcha y evaluación de la aplicación Web, TeleOftalWeb, en sus cuatro versiones, destinada al almacenamiento e intercambio de Historiales Clínicos Electrónicos (HCEs) y retinografías. Cada una de las versiones está desarrollada con diferentes modelos de bases de datos (BDs): dbXML 2.0 más MySQL 5.0, eXist 1.1.1 más MySQL, Xindice 1.2. más MySQL 5.0 y Oracle 10g. A su vez, se estudiarán los estándares de HCE más relevantes entre ello...

  5. Analytic properties of high energy production amplitudes in N=4 SUSY

    Energy Technology Data Exchange (ETDEWEB)

    Lipatov, L.N. [St. Petersburg Inst. of Nuclear Physics, Gatchina (Russian Federation); Hamburg Univ. (Germany). 1. Inst. fuer Theoretische Physik

    2010-08-15

    We investigate analytic properties of the six point planar amplitude in N=4 SUSY at the multi-Regge kinematics for final state particles. For inelastic processes the Steinmann relations play an important role because they give a possibility to fix the phase structure of the Regge pole and Mandelstam cut contributions. The analyticity and factorization constraints allow us to reproduce the two-loop correction to the 6- point BDS amplitude in N=4 SUSY obtained earlier in the leading logarithmic approximation with the use of the s-channel unitarity. The cut contribution has the Moebius invariant form in the transverse momentum subspace. The exponentiation hypothesis for the amplitude in the multi-Regge kinematics is also investigated in LLA. (orig.)

  6. The Genetic diversity of Bangladeshi Buffaloes

    Directory of Open Access Journals (Sweden)

    M.O. Faruque

    2010-02-01

    Full Text Available The most buffaloes in Bangladesh are indigenous in origin. There are 5 populations of buffaloes in Bangladesh. Karyotypic experiment indicated that Bangladesh East population had 48 chromosomes while other populations had 50 chromosomes. Blood protein polymorphism study revealed the existence of polymorphism for 7 loci: albumin, transferrin, hemoglobin-α, hemoglobin-β, carbonic anhydrase, alkaline phosphatase and peptidase-B. AlbX, gene for typical swamp buffalo, was detected in populations of BDE and BDS. Another gene of swamp buffalo viz., TfA was found only in the population of BDE. mtDNA study further confirmed the occurrence of haplotypes for swamp buffaloes in BDE. Swamp buffaloes are distributed in the northeastern part of Bangladesh. River buffaloes are distributed other parts of Bangladesh.

  7. Molecular probe dynamics and free volume in organic glass-formers and their relationships to structural relaxation: 1-propanol

    International Nuclear Information System (INIS)

    A joint study of the rotational dynamics and free volume in amorphous 1-propanol (1-PrOH) as a prototypical monohydroxy alcohol by electron spin resonance (ESR) or positron annihilation lifetime spectroscopy (PALS), respectively, is reported. The dynamic parameters of the molecular spin probe 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO) and the annihilation ones of the atomic ortho-positronium (o-Ps) probe as a function of temperature are compared. A number of coincidences between various effects in the ESR and PALS responses at the corresponding characteristic ESR and PALS temperatures were found suggesting a common origin of the underlying dynamic processes that were identified using viscosity (VISC) in terms of the two-order parameter (TOP) model and broadband dielectric spectroscopy (BDS) data. (paper)

  8. High performance liquid chromatography with immobilized Ru(bpy)32+-KMn04 chemiluminescence detection and its application in metabolism of repaglinide in pig liver microsomes

    Institute of Scientific and Technical Information of China (English)

    Ai Hua Fu; Zhu Jun Zhang; Li Li Chen; Xiao Ming Zhang; Pan Xue

    2011-01-01

    A novel high performance liquid chromatography-chemiluminescence (HPLC-CL) method for investigation of in vitro metabolism of repaglinide in pig liver microsomes with microdialysis sampling technique was developed. The chromatographic separation was performed on a Hypersil BDS-C18 column with an isocratic mobile phase consisting of methanol and 0.01 mol/L KH2PO4 (pH 3.0) (volume ratio 75:25) at a flow rate of 1.0 mL/min. The detection was based on the chemiluminescence reaction of repaglinide with acidic potassium permanganate (KMnO4) and tris (2,2'-bipyridyl)ruthenium(III) (Ru(bpy)33+), which was immobilized on the cationic ion-exchange resin for obtaining high sensitivity and reducing consumption of expensive reagent.

  9. Detectability of substellar companions around white dwarfs with Gaia

    CERN Document Server

    Silvotti, Roberto; Lattanzi, Mario; Morbidelli, Roberto

    2014-01-01

    To date not a single-bona fide planet has been identified orbiting a single white dwarf. In fact we are ignorant about the final configuration of >95% of planetary systems. Theoretical models predict a gap in the final distribution of orbital periods, due to the opposite effects of stellar mass loss (planets pushed outwards) and tidal interactions (planets pushed inwards) during the RGB and the AGB stellar expansions. Over its five year primary mission, Gaia is expected to astrometrically detect the first (few tens of) WD massive planets/BDs giving first evidence that WD planets exist, at least those in wide orbits. In this article we present preliminary results of our simulations of what Gaia should be able to find in this field.

  10. RP-HPLC METHOD FOR SIMULTATANEOUS DETERMINATION OF IRBESARTAN, LOSARTAN, HYDRO-CHLOROTHIAZIDE AND CHLORTHALIDONE–APPLICATION TO COMMERCIALLY AVAILABLE DRUG PRODUCTS

    Directory of Open Access Journals (Sweden)

    R. A. Mhaske et al.

    2012-04-01

    Full Text Available A simple, precise and stability-indicating HPLC method was developed and validated for the simultaneous determination of anti-hypertensive drugs Irbesartan, Losartan, diuretics Hydrochlorothiazide and Chlorthalidone. The separation was achieved on Hypersil BDS (Length 250 mm × Diameter 4.6 mm Particle size 5 μm column with gradient flow. The mobile phase at a flow rate of 1.0 mL min−1 consisted of 0.05 M sodium dihydrogen phosphate buffer and acetonitrile (Gradient ratio. The UV detection was carried out at 220 nm. The method was successfully validated in accordance to ICH guidelines. Further, the validated method was applied for commercially available pharmaceutical dosage form.

  11. Temperature dependence of the dielectric constant of acrylic dielectric elastomer

    Energy Technology Data Exchange (ETDEWEB)

    Sheng, Junjie; Chen, Hualing; Li, Bo; Chang, Longfei [Xi' an Jiaotong University, State Key Laboratory for Strength and Vibration of Mechanical Structures, Xi' an (China); Xi' an Jiaotong University, School of Mechanical Engineering, Xi' an (China)

    2013-02-15

    The dielectric constant is an essential electrical parameter to the achievable voltage-induced deformation of the dielectric elastomer. This paper primarily focuses on the temperature dependence of the dielectric constant (within the range of 173 K to 373 K) for the most widely used acrylic dielectric elastomer (VHB 4910). First the dielectric constant was investigated experimentally with the broadband dielectric spectrometer (BDS). Results showed that the dielectric constant first increased with temperature up to a peak value and then dropped to a relative small value. Then by analyzing the fitted curves, the Cole-Cole dispersion equation was found better to characterize the rising process before the peak values than the Debye dispersion equation, while the decrease process afterward can be well described by the simple Debye model. Finally, a mathematical model of dielectric constant of VHB 4910 was obtained from the fitted results which can be used to further probe the electromechanical stability of the dielectric elastomers. (orig.)

  12. Comparison of the rat and mouse cell lines commercially available for CALUX bioassays

    Energy Technology Data Exchange (ETDEWEB)

    Goeyens, L.; Windal, I.; Wouwe, N. van [Institute of Public Health, Brussels (Belgium); Scippo, M.L.; Eppe, G.; Pauw, E. de; Maghin-Rogister, G. [Liege Univ. (Belgium)

    2004-09-15

    CALUX (Chemical-activated luciferase gene expression) is nowadays more and more widely used, both for the control of the norms applied to the food chain and to environmental contamination evaluation. In that purpose, two cell lines are commercially available: one rat cell line, commercialized by Bio Detection System (BDS, The Netherlands) and one mouse cell line, commercialized by Xenobiotic Detection System (XDS, USA). Both suppliers propose different clean-up methods and a slightly different method in the preparation, dosage and reading of the plates. Until now, almost no comparison of the cell lines has been performed, or the comparison includes many variables (extraction, purification, method of preparation, dosage and reading of the plate) so that it is difficult to evaluate which variables are mainly responsible of the observed differences. The objective of the research presented here is to perform a direct comparison of the 2 cell lines, and evaluate which variables can be responsible of the discrepancy observed between the results.

  13. MICROLENSING DISCOVERY OF A POPULATION OF VERY TIGHT, VERY LOW MASS BINARY BROWN DWARFS

    International Nuclear Information System (INIS)

    Although many models have been proposed, the physical mechanisms responsible for the formation of low-mass brown dwarfs (BDs) are poorly understood. The multiplicity properties and minimum mass of the BD mass function provide critical empirical diagnostics of these mechanisms. We present the discovery via gravitational microlensing of two very low mass, very tight binary systems. These binaries have directly and precisely measured total system masses of 0.025 M☉ and 0.034 M☉, and projected separations of 0.31 AU and 0.19 AU, making them the lowest-mass and tightest field BD binaries known. The discovery of a population of such binaries indicates that BD binaries can robustly form at least down to masses of ∼0.02 M☉. Future microlensing surveys will measure a mass-selected sample of BD binary systems, which can then be directly compared to similar samples of stellar binaries.

  14. Application of Modular Technology of Tightly-coupled GPS/INS%GPS/INS深组合技术及其应用

    Institute of Scientific and Technical Information of China (English)

    周坤芳; 任卓谊

    2016-01-01

    分析GPS/INS深组合结构,研究INS信息辅助GPS接收机基带环路技术,仿真研究GPS/INS深组合模式特性,其具有提高接收机动态适应能力、抗干扰能力、伪距测量精度等特性,拓展了卫星导航的应用范围.随着BDS具备亚太区域导航能力,鉴借GPS/INS深组合技术,分析BDS/INS深组合中的若干技术问题,以供相关人士研究参考.

  15. Stability-indicating RP-HPLC method for simultaneous determination of gatifloxacin and flurbiprofen in binary combination

    Directory of Open Access Journals (Sweden)

    Islam Ullah Khan

    2014-04-01

    Full Text Available A stability-indicating RP-HPLC method is presented for determination of gatifloxacin and flurbiprofen in binary combination. Gatifloxacin, flurbiprofen and their degradation products were detected at 254 nm using a BDS Hypersil C8 (250 X 4.6 mm, 5 µm column and mixture of 20 mM phosphate buffer (pH 3.0 and methanol 30:70 v/v as mobile phase. Response was linear over the range of 15-105 mg mL-1 for gatifloxacin (r² > 0.998 and of 1.5-10.5 mg mL-1 for flurbiprofen (r² > 0.999. The developed method efficiently separated the analytical peaks from degradation products (peak purity index > 0.9999. The method developed can be applied successfully for determination of gatifloxacin and flurbiprofen in human serum, urine, pharmaceutical formulations, and their stability studies.

  16. Continuing professional development of dentists through distant learning: An Indira Gandhi National Open University-Dental Council of India experiment a report

    Directory of Open Access Journals (Sweden)

    Ruchika Kuba

    2014-01-01

    Full Text Available To keep themselves updated with all the advancements in the field of dentistry, dentists should involve themselves in some kind of professional development. Distance learning is the most appropriate way to serve the growing demand due to technological advancements. Indira Gandhi National Open University in collaboration with Dental Council of India (DCI developed and launched two continuing professional development programs in Endodontics (postgraduate certificate in endodontics and postgraduate certificate in oral implantology and has trained over 400 and 280 BDS dentists respectively till date. The program package consists of self-instructional material, assignments, videos and practical training. The training is conducted in premiere dental colleges and institutions recognized by DCI. The certificate is awarded after a term end examination, both in theory and practical. The pass percentages of the theory courses ranged from around 63% to 98%, and 90% of the candidates cleared the practical exam.

  17. Some Notes on Interoperability of GNSS

    Directory of Open Access Journals (Sweden)

    YANG Yuanxi

    2016-03-01

    Full Text Available Compatibility and interoperability of GNSS are the hot research issues in international satellite navigation field. It is a requirement for integrated multi GNSS navigation and positioning. The basic concepts of the compatibility and interoperability are introduced and the trend of the interoperability among the GNSS providers is discussed. The status and problems of the frequency interoperability of GPS, BeiDou(BDS, GLONASS and Galileo are analyzed. It is pointed that the frequency interoperability problems will affect the manufacturers and multi GNSS users. The influences of the interoperability problems of the reference coordinate systems are not only resulted from the definitions and realizations of the reference coordinate systems but also from the maintenance and update strategies of the reference systems. The effects of the time datum interoperability and corresponding resolving strategies are also discussed. The influences of the interoperability problems of GNSS are summarized.

  18. Determination of racecadotril by HPLC in capsules

    Directory of Open Access Journals (Sweden)

    Prabu S

    2007-01-01

    Full Text Available A simple, precise and rapid RP-HPLC method was developed for the determination of racecadotril in a pharmaceutical formulation using gemfibrozil as internal standard. Ratio of the peak area of analyte to internal standard was used for quantification. The chromatographic separation was carried out by using a Reverse Phase C18 column (BDS-Hypersil. The mobile phase consisting of a mixture of 20 mM phosphate buffer (pH 3.5 and acetonitrile in the ratio of (40:60 with detection at 230 nm at a flow rate of 1 ml/min was employed. The method was statistically validated for linearity, accuracy and precision. The elution time was 6.9 min for racecadotril and 9.8 min for gemfibrozil. The simplicity and accuracy of the proposed method ensures its use in routine quality control analysis of pharmaceutical formulations.

  19. Thermo-mechanical Analysis of the CLIC Post-Linac Energy Collimators

    CERN Document Server

    Resta-Lopez, J; Latina, A

    2012-01-01

    The post-linac energy collimation system of the Compact Linear Collider (CLIC) has been designed for passive protection of the Beam Delivery System (BDS) against miss-steered beams due to failure modes in the main linac. In this paper, a thermo-mechanical analysis of the CLIC energy collimators is presented. This study is based on simulations using the codes FLUKA and ANSYS when an entire bunch train hits the collimators. Different failure mode scenarios in the main linac are considered. The aim is to improve the collimator in order to make a reliable and robust design so that survives without damage the impact of a full bunch train in case of likely events generating energy errors.

  20. Flow-induced scission of macromolecules

    Science.gov (United States)

    Sim, H.

    2005-11-01

    Mechanical scission of long chain synthetic and bio- polymers in strong flows is pertinent to applications ranging from genomics to polymer-induced turbulent drag reduction. Experiments generally differentiate between two types of fracture mechanisms in extensional flows depending on whether the polymer experiences a steady (e.g. cross slot flow) or transient (e.g. contraction flow) field. Theories based on ``mid-point scission hypothesis'' as well as computer simulations using bead-spring models that use ad hoc energy-based criteria have been used to explain experimental observations. We present the results of a study that for the first time couples Brownian Dynamics Simulation (BDS) using bead-rod (Kramers) chains with a novel algorithm for the determination of scission events which themselves are stochastic processes. Flexible lambda-phage DNA is selected as a model molecule. We will discuss effect of molecular weight (MW), flow type and hydrodynamic interactions on chain scission and the MW distribution.

  1. New titrimetric method for oxygen to metal ratio in uranium oxide powders

    International Nuclear Information System (INIS)

    O/U ratio is of high importance to both U3O8 and UO2 powders for different reasons. In UO2 powder it is a guiding parameter for sintering process where as for U3O8, it indicates efficiency of ammonium di-uranate (ADU) to U3O8 conversion process. In the present method for O/U determination, UO2 and U3O8 powders are dissolved in 4.5 M sulphuric acid and little HF by heating on hot plate. Subsequently, optimized quantity of phosphoric acid is added on cooling, for getting sharp end point. The resultant solution is titrated with standard potassium dichromate using barium diphenylamine sulphonate (BDS) as an indicator. The expanded uncertainties calculated for UO2 and U3O8 powders are ±0.004 and ±0.006 O/U ratio units respectively at 95 % confidence level. (author)

  2. Cold Brown Dwarfs with WISE: Y Dwarfs and the Field Mass Function

    Science.gov (United States)

    Kirkpatrick, J. Davy

    2012-01-01

    Why study Brown Dwarf stars? They re the lowest mass byproducts of star formation.. They provide time capsules across the age of the Galaxy.. They show what low-T(sub eff) atmospheres look like.. They may be some of our closest neighbors in space..WISE is a 40cm Earth-orbiting telescope. There are 211 stars and only 33 brown dwarfs in this volume.. This means that stars outnumber brown dwarfs by a factor of 6:1 currently.. The number of brown dwarfs will continue to increase if:: (a) more nearby Y dwarf candidates are confirmed, or (b) our distances to known Y s are overestimated, or (c) there are colder BDs invisible to WISE..

  3. Measurement of the Absolute Branching Fraction of D_s^+ --> tau^+ nu_tau Decay

    CERN Document Server

    Ecklund, K M; Savinov, V; López, A; Méndez, H; Ramírez, J; Ge, J Y; Miller, D H; Shipsey, I P J; Xin, B; Adams, G S; Anderson, M; Cummings, J P; Danko, I; Hu, D; Moziak, B; Napolitano, J; He, Q; Insler, J; Muramatsu, H; Park, C S; Thorndike, E H; Yang, F; Artuso, M; Blusk, S; Khalil, S; Li, J; Mountain, R; Nisar, S; Randrianarivony, K; Sultana, N; Skwarnicki, T; Stone, S; Wang, J C; Zhang, L M; Bonvicini, G; Cinabro, D; Dubrovin, M; Lincoln, A; Rademacker, J; Asner, D M; Edwards, K W; Naik, P; Reed, J; Briere, R A; Ferguson, T; Tatishvili, G; Vogel, H; Watkins, M E; Rosner, J L; Alexander, J P; Cassel, D G; Duboscq, J E; Ehrlich, R; Fields, L; Gibbons, L; Gray, R; Gray, S W; Hartill, D L; Heltsley, B K; Hertz, D; Jones, C D; Kandaswamy, J; Kreinick, D L; Kuznetsov, V E; Mahlke-Krüger, H; Mohapatra, D; Onyisi, P U E; Patterson, J R; Peterson, D; Riley, D; Ryd, A; Sadoff, A J; Shi, X; Stroiney, S; Sun, W M; Wilksen, T; Athar, S B; Patel, R; Yelton, J; Rubin, P; Eisenstein, B I; Karliner, I; Mehrabyan, S; Lowrey, N; Selen, M; White, E J; Wiss, J; Mitchell, R E; Shepherd, M R; Besson, D; Pedlar, T K; Cronin-Hennessy, D; Gao, K Y; Hietala, J; Kubota, Y; Klein, T; Lang, B W; Poling, R; Scott, A W; Zweber, P; Dobbs, S; Metreveli, Z; Seth, K K; Tomaradze, A G; Libby, J; Powell, A; Wilkinson, G

    2007-01-01

    Using a sample of tagged D_s decays collected near the D^*_s D_s peak production energy with the CLEO-c detector, we study the leptonic decay D^+_s to tau^+ nu_tau via the decay channel tau^+ to e^+ nu_e bar{nu}_tau. We measure B(D^+_s to tau^+ nu_tau) = (6.17 +- 0.71 +- 0.34) %. Combining with our measurements of D^+_s to mu^+ nu_mu and D^+_s to tau^+ nu_tau (via tau^+ to pi^+ bar{nu}_tau), we determine f_{D_s} = 274 +- 10 +- 5 MeV.

  4. Are oil markets chaotic? A non-linear dynamic analysis

    International Nuclear Information System (INIS)

    The analysis of products' price behaviour continues to be an important empirical issue. This study contributes to the current literature on price dynamics of products by examining for the presence of chaos and non-linear dynamics in daily oil products for the Rotterdam and Mediterranean petroleum markets. Previous studies using only one invariant, such as the correlation dimension may not effectively determine the chaotic structure of the underlying time series. To obtain better information on the time series structure, a framework is developed, where both invariant and non-invariant quantities were also examined. In this paper various invariants for detecting a chaotic time series were analysed along with the associated Brock's theorem and Eckman-Ruelle condition, to return series for the prices of oil products. An additional non-invariant quantity, the BDS statistic, was also examined. The correlation dimension, entropies and Lyapunov exponents show strong evidence of chaos in a number of oil products considered. 30 refs

  5. BFKL Pomeron and Bern-Dixon-Smirnov amplitudes in N=4 SUSY

    International Nuclear Information System (INIS)

    We review the theoretical approaches for investigations of the high energy hadron-hadron scattering in the Regge kinematics. It is demonstrated, that the gluon in QCD is reggeized and the Pomeron is a composite state of the reggeized gluons. Remarkable properties of the BFKL equation for the Pomeron wave function in QCD and supersymmetric gauge theories are outlined. Due to the AdS/CFT correspondence the BFKL Pomeron is equivalent to the reggeized graviton in the extended N=4 SUSY. The properties of the maximal transcendentality and integrability are realized in this model. The BDS multi-gluon scattering amplitudes are investigated in the Regge limit. They do not contain the Mandelstam cuts and are not valid beyond one loop. It is shown, that the hamiltonian for these composite states coincides with the hamiltonian of an integrable open Heisenberg spin chain. (orig.)

  6. Simultaneous determination of cefixime trihydrate and dicloxacillin sodium in pharmaceutical dosage form by reversed-phase high-performance liquid chromatography.

    Science.gov (United States)

    Dhoka, Madhura V; Sandage, Shakuntala J; Dumbre, Snehal C

    2010-01-01

    A simple, precise, accurate, and sensitive RP-HPLC method for simultaneous determination of cefixime trihydrate and dicloxacillin sodium in combined tablet dosage form was developed and validated. Chromatographic separation of the two drugs was performed on a Purospher BDS C18 column (25 cm x 4.6 mm id, 5 microm particle size). The mobile phase methanol-0.01 M phosphate buffer (75 + 25, v/v), adjusted to pH 3 with glacial acetic acid, was delivered at a flow rate of 1.0 mL/min. Detection was performed at 227 nm. Separation was completed within 10 min. Calibration curves were linear with R2 between 0.99 to 1.0 over a concentration range of 2-10 microg/mL for cefixime trihydrate and 5-25 micromL for dicloxacillin sodium. The RSD for intraday and interday precision was < 2.0%. PMID:20480900

  7. Catalytic conversion of xylose and corn stalk into furfural over carbon solid acid catalyst in γ-valerolactone.

    Science.gov (United States)

    Zhang, Tingwei; Li, Wenzhi; Xu, Zhiping; Liu, Qiyu; Ma, Qiaozhi; Jameel, Hasan; Chang, Hou-Min; Ma, Longlong

    2016-06-01

    A novel carbon solid acid catalyst was synthesized by the sulfonation of carbonaceous material which was prepared by carbonization of sucrose using 4-BDS as a sulfonating agent. TEM, N2 adsorption-desorption, elemental analysis, XPS and FT-IR were used to characterize the catalyst. Then, the catalyst was applied for the conversion of xylose and corn stalk into furfural in GVL. The influence of the reaction time, temperature and dosage of catalyst on xylose dehydration were also investigated. The Brønsted acid catalyst exhibited high activity in the dehydration of xylose, with a high furfural yield of 78.5% at 170°C in 30min. What's more, a 60.6% furfural yield from corn stalk was achieved in 100min at 200°C. The recyclability of the sulfonated carbon catalyst was perfect, and it could be reused for 5times without the loss of furfural yields. PMID:26967333

  8. 人参提取物中腐霉利残留的HPLC分析%Analysis of Procymidone Residues in Ginseng Extract by HPLC

    Institute of Scientific and Technical Information of China (English)

    任刚; 廖卫波; 胡志成; 易文芳; 刘荣华; 邵峰; 黄慧莲; 袁金斌

    2013-01-01

    目的:建立人参提取物中农药残留-腐霉利的HPLC含量测定方法.方法:BDS HYPERSIL C18分析色谱柱(4.6 mm × 250 mm,5 μm),流动相乙腈-水(40∶ 60),流速1.0 mL· min-1,检测波长220 nm.结果:腐霉利进样量0.001~0.6 μg与色谱峰面积呈良好线性关系(R2 =0.999 4),平均加样回收率100.0% (n=9),RSD 3.0%.结论:该法简便、准确、可靠,可用于人参提取物中腐霉利残留的含量测定.

  9. On a residual freedom of the next-to-leading BFKL eigenvalue in color adjoint representation in planar $\\mathcal{N} = 4$ SYM

    CERN Document Server

    Bondarenko, Sergey

    2016-01-01

    We discuss a residual freedom of the next-to-leading BFKL eigenvalue that originates from ambiguity in redistributing the next-to-leading~(NLO) corrections between the adjoint BFKL eigenvalue and eigenfunctions in planar $\\mathcal{N}=4$ super-Yang-Mills~(SYM) Theory. In terms of the remainder function of the Bern-Dixon-Smirnov~(BDS) amplitude this freedom is translated to reshuffling correction between the eigenvalue and the impact factors in the multi-Regge kinematics~(MRK) in the next-to-leading logarithm approximation~(NLA). We show that the modified NLO BFKL eigenvalue suggested by the authors can be introduced in the MRK expression for the remainder function by shifting the anomalous dimension in the impact factor in such a way that the two and three loop remainder function is left unchanged to the NLA accuracy.

  10. Analytical Method Development and Validation of Related Substance Method for Bortezomib for Injection 3.5 mg/Vial by RP-HPLC Method

    Directory of Open Access Journals (Sweden)

    Utage M

    2013-04-01

    Full Text Available An accurate, precise, simple and economical High Performance Liquid Chromatographic method for therelated substance determination of Bortezomib in its lyophilized dosage form has been developed. Themethod developed is Reverse Phase High Performance Liquid Chromatographic method using HypersilBDS C18 column (Length: 150mm, Diameter: 4.6mm, Particle size: 5μ with Gradient programmed anda simple Acetonitrile, Water and Formic acid in the ratio of 30:70:0.1 (v/v/v respectively as mobilephase A and Acetonitrile, Water and Formic acid in the ratio of 80:20:0.1 (v/v/v respectively. Themethod so developed was validated in compliance with the regulatory guidelines by using welldeveloped analytical method validation tool which comprises with the analytical method validationparameters like Linearity, Accuracy, Method precision, Specificity with forced degradation, Systemsuitability, Robustness, LOD, LOQ and Ruggedness. The results obtained were well within theacceptance criteria.

  11. HPLC Method for the Determination of Tamsulosin Hydrochloride in Sustained Release Tablets

    Institute of Scientific and Technical Information of China (English)

    齐美玲; 王鹏; 耿颖姝; 顾峻岭

    2003-01-01

    The development and validation of an isocratic high performance liquid chromatographic method is described for the determination of tamsulosin hydrochloride in sustained release tablets. The determination was performed on a Diamonsil BDS C18 column with a mobile phase consisting of a mixture of acetonitrile, methanol and 0.5% phosphoric acid solution (20∶30∶50,V/V/V) at a flow rate of 1.0 mL/min. UV detection was made at 274 nm. The linear range for tamsulosin hydrochloride was 0.81-8.10 μg/mL. The mean recovery was 99.8% (SR=0.7%, n=9), and the precision was found to be 0.45% (n=9). The proposed method can be used for routine analysis of tamsulosin hydrochloride in sustained release tablets.

  12. Quelles sont les rôles de l'infirmière dans l'accompagnement à moyen terme d'une personne adulte ayant eu un AVC ?

    OpenAIRE

    Schouller, Léane; Ali, Fartun; Muriset, Tifany; Guye, Anne-Lise

    2016-01-01

    Problématique : Difficulté pour les infirmières et les différents professionnels de la santé de reconnaître et définir la place de l’infirmière dans un service de réadaptation. Objectifs : Définir le rôle de l’infirmière au sein d’une équipe interdisciplinaire dans un service de réadaptation et trouver les interventions spécifiques qu’elles peuvent mettre en place afin d’améliorer la qualité de la prise en charge du BDS. Concepts abordés : Les concepts abordés dans ce travail sont l’AVC, l’in...

  13. Effect of consanguinity on birth defects in Saudi women; results from a nested case-control study

    DEFF Research Database (Denmark)

    Majeed-Saidan, Muhammad Ali; Ammari, Amer N; AlHashem, Amal M;

    2015-01-01

    : This case and control study was nested within a 3-year prospective cohort study to examine patterns of fetal and neonatal malformations in Saudi women at Prince Sultan Military Medical City (PSMMC), Riyadh -Saudi Arabia. Consanguineous marriages were defined as marriages with first or second cousins......BACKGROUND: The role of consanguinity in the etiology of structural birth defects outside of chromosomal and inherited disorders has always been debated. We studied the independent role of consanguinity on birth defects in Saudi women with a high prevalence of consanguineous marriages. METHODS...... consanguinity prevalence for all included women was 49.6%. The consanguinity among babies with major Birth Defects (BDs) was 54.5% and 45.2% for controls (P < 0.0002). The prevalence of major birth defects was 41.1 per 1000 total births. Univariate analysis showed that consanguinity had a statistically...

  14. Biological Threats Detection Technologies

    International Nuclear Information System (INIS)

    Among many decisive factors, which can have the influence on the possibility of decreases the results of use biological agents should be mentioned obligatory: rapid detection and identification of biological factor used, the proper preventive treatment and the medical management. The aims of identification: to identify the factor used, to estimate the area of contamination, to evaluate the possible countermeasure efforts (antibiotics, disinfectants) and to assess the effectiveness of the decontamination efforts (decontamination of the persons, equipment, buildings, environment etc.). The objects of identification are: bacteria and bacteria's spores, viruses, toxins and genetically modified factors. The present technologies are divided into: based on PCR techniques (ABI PRISM, APSIS, BIOVERIS, RAPID), immuno (BADD, RAMP, SMART) PCR and immuno techniques (APDS, LUMINEX) and others (BDS2, LUNASCAN, MALDI). The selected technologies assigned to field conditions, mobile and stationary laboratories will be presented.(author)

  15. Thermal, structural and electrical studies of bismuth zinc borate glasses

    Science.gov (United States)

    Shanmugavelu, B.; Ravi Kanth Kumar, V. V.

    2013-06-01

    Bismuth Zinc Borate glasses with compositions xBi2O3-30ZnO-(70 - x)B2O3 (where x = 30, 35, 40 and 45 mol %) have been prepared by melt quenching method. These glasses were characterized by X-ray diffraction (XRD), Differential Thermal Analysis (DTA), Fourier Transform Infrared Spectrometer (FTIR) and Broad Band Dielectric Spectrometer (BDS). DTA and FTIR analysis reveals that Non-Bridging Oxygens (NBOs) increase with increase of bismuth content in the glass. Electrical data have been analyzed in the framework of impedance and modulus formalisms. The activation energy for dc conductivity decreases with increase of bismuth concentration. The imaginary part of modulus spectra has been fitted to non-exponential Kohlrausch-Williams-Watts (KWW) function and the value of the stretched exponent (β) is found to be almost independent of temperature but slightly dependent on composition.

  16. Determination of grass enema Verbena gallic acid in by HPLC%HPLC法测定地锦草灌肠液中没食子酸的含量

    Institute of Scientific and Technical Information of China (English)

    佘永红; 周顺

    2011-01-01

    目的:建立地锦草灌肠液中没食子酸的含量测定.方法:采用HPLC法,色谱柱为BDS Hypersil C18(250 mm×4.6mm,5μm);流动相为甲醇-0.05%磷酸溶液(10∶90);流速为0.8 mL·min-1;检测波长为266 nm;柱温为室温,进样量为10 μL.结果:没食子酸在0.07116-0.49812 μg范围内呈良好的线形关系(r=0.9998),平均回收率为100.7%,RSD%为1.1%(n=6).结论:该方法简便,准确,重现性好,可用于地锦草灌肠液的质量控制.%Objective: To establish a creeper grass enema Determination of gallic acid. Methods: HPLC,column was BDS Hypersil C18(25 mmx4.6 mm,5 μm), mobile phase of methanol-0.05% phosphoric acid water(10∶90), flow rate of 0.8 mL-min-1,the detection wavelength was 266 nm, column temperature was room temperature, the injection volume was 10 μL.Results:Gallic acid in the range of 0.07116-0.49812 μg showed a good linear relationship (r=0.9998),the average recovery was100.7%,RSD% was 1.1% (n=6).Conclusion: The method is simple, accurate, reproducible, and can be used for Euphorbia humifusa enema quality control.

  17. Engineered safety in development of liquid poison injection system (shut down system-2) for 500 MWe PHWR

    International Nuclear Information System (INIS)

    Full text: The provision of shut down systems (SDS) is a mandatory requirement for safety of any nuclear reactor. The SDS shall be capable of making and holding the core adequately subcritical in the event of any anticipated operational occurrence and postulated accident conditions. The shut down function will perform as intended when its design and components are thoroughly evaluated for their reliability and effectiveness. A full scale mock up for one injection unit was designed and developed at Hall No.7, BARC. Experimental studies were carried out to qualify the design and evolve process parameters such as gas tank pressure, poison discharge rate and poison injection time. In liquid poison injection system i.e. shutdown system -2, there is no physical barrier, between the two liquids i.e. the poison and the moderator. A liquid in liquid interface, called poison moderator interface (PMI) separates these fluids. Extensive lab scale studies have been carried out on PMI movement study i.e. the interface movement due to molecular diffusion and due to process disturbances under simulated reactor condition. On the basis of lab scale results, a full-scale PMI setup has been designed and developed to generate plant data. From reactor safety consideration, the floating ball in poison tank is designed in such a way that it prevents the over pressurisation of calandria. For this purpose a non-intrusive ultrasonic ball detection system (U-BDS) has been developed. This paper covers the PMI system for 500 MWe PHWR with relevant safety aspects and describes in detail, the experimental results of PMI study. The engineered safety in design, methodology and qualification of U-BDS and its role intended in performance of SDS-2 have been also discussed in the paper

  18. Crystallization behavior and dielectric properties of K{sub 2}O–SrO–Nb{sub 2}O{sub 5}–B{sub 2}O{sub 3}–Al{sub 2}O{sub 3}–SiO{sub 2} glass-ceramic for energy storage

    Energy Technology Data Exchange (ETDEWEB)

    Xiao, Shi; Xiu, Shaomei; Xue, Shuangxi; Shen, Bo; Zhai, Jiwei, E-mail: apzhai@tongji.edu.cn

    2015-11-05

    A new K{sub 2}O–SrO–Nb{sub 2}O{sub 5}–B{sub 2}O{sub 3}–Al{sub 2}O{sub 3}–SiO{sub 2} (KSN-BAS) glass-ceramic system has been prepared by conventional controlled-crystallization method. The crystallization behavior and dielectric properties of the glass-ceramics were investigated. The X-ray diffraction analysis showed that the KSr{sub 2}Nb{sub 5}O{sub 15} and SrNb{sub 2}O{sub 6} phases with tungsten bronze structure were precipitated from the glass matrix, as the crystallization temperature increased, the AlNbO{sub 4} phase was observed. The microstructure observed the sizes of grains became larger and presented the grain reunion severely. The dielectric constants of all the samples exhibited excellent stability from −90 °C to 120 °C and low dielectric losses less than 0.03. A maximum dielectric constant was obtained at annealing of 900 °C. The dielectric breakdown strength (BDS) reduced as the crystallization temperature increased. A maximum BDS can attain1213.76 kV/cm and a maximum energy storage density can reach up to 4.41 J/cm{sup 3}. - Highlights: • The energy storage density of original glass-ceramic can reach to 4.41 J/cm{sup 3}. • The single phase of high dielectric constant can be found in this glass-ceramic. • The material is regarded as a linear material without any ferroelectric behavior. • The heat treatment method is used to study the new glass-ceramic system. • The paper elaborated the effect of crystallization temperature on the properties.

  19. Influence of oxygen transfer on Pseudomonas putida effects on growth rate and biodesulfurization capacity.

    Science.gov (United States)

    Escobar, S; Rodriguez, A; Gomez, E; Alcon, A; Santos, V E; Garcia-Ochoa, Felix

    2016-04-01

    The growth rate and desulfurization capacity accumulated by the cells during the growth of Pseudomonas putida KTH2 under different oxygen transfer conditions in a stirred and sparged tank bioreactor have been studied. Hydrodynamic conditions were changed using different agitation conditions. During the culture, several magnitudes associated to growth, such as the specific growth rate, the dissolved oxygen concentration and the carbon source consumption have been measured. Experimental results indicate that cultures are influenced by the fluid dynamic conditions into the bioreactor. An increase in the stirrer speed from 400 to 700 rpm has a positive influence on the cell growth rate. Nevertheless, the increase of agitation from 700 to 2000 rpm hardly has any influence on the growth rate. The effect of fluid dynamics on the cells development of the biodesulfurization (BDS) capacity of the cells during growth is different. The activities of the intracellular enzymes involved in the 4S pathway change with dissolved oxygen concentration. The enzyme activities have been evaluated in cells at several growth time and different hydrodynamic conditions. An increase of the agitation from 100 to 300 rpm has a positive influence on the development of the overall BDS capacity of the cells during growth. This capacity shows a decrease for higher stirrer speeds and the activity of the enzymes monooxygenases DszC and DszA decreases dramatically. The highest value of the activity of DszB enzyme was obtained with cells cultured at 100 rpm, while this activity decreases when the stirrer speed was increased higher than this value. PMID:26762940

  20. Flash ionization signature in coherent cyclotron emission from brown dwarfs

    Science.gov (United States)

    Vorgul, I.; Helling, Ch.

    2016-05-01

    Brown dwarfs (BDs) form mineral clouds in their atmospheres, where charged particles can produce large-scale discharges in the form of lightning resulting in substantial sudden increase of local ionization. BDs are observed to emit cyclotron radio emission. We show that signatures of strong transient atmospheric ionization events (flash ionization) can be imprinted on a pre-existing radiation. Detection of such flash ionization events will open investigations into the ionization state and atmospheric dynamics. Such events can also result from explosion shock waves, material outbursts or (volcanic) eruptions. We present an analytical model that describes the modulation of a pre-existing electromagnetic radiation by a time-dependent (flash) conductivity that is characteristic for flash ionization events like lightning. Our conductivity model reproduces the conductivity function derived from observations of terrestrial gamma-ray flashes, and is applicable to astrophysical objects with strong temporal variations in the local ionization, as in planetary atmospheres and protoplanetary discs. We show that the field responds with a characteristic flash-shaped pulse to a conductivity flash of intermediate intensity. More powerful ionization events result in smaller variations of the initial radiation, or in its damping. We show that the characteristic damping of the response field for high-power initial radiation carries information about the ionization flash magnitude and duration. The duration of the pulse amplification or the damping is consistently shorter for larger conductivity variations and can be used to evaluate the intensity of the flash ionization. Our work suggests that cyclotron emission could be probe signals for electrification processes inside BD atmosphere.

  1. Effect of Media on Gynogenesis Induction in Leek (allium ampeloprasum L. Breeding Materials

    Directory of Open Access Journals (Sweden)

    A. KASKA

    2014-06-01

    Full Text Available Leek (Allium ampeloprasum L. is one of the economically important members of the genus Allium (family:Alliaceae. It is a self-compatible, outbreeding, tetraploid (2n=4X= 32 crop species that is very difficult to improve through traditional breeding strategies. Entegration of doubled haploid (DH techniques such as gynogenesis into the leek breeding programs may speed up the variety development. In order to optimize a gynogenesis induction protocol for leek, we carried out experiments by culturing immature flower buds on various tissue culture media. Among the media tested, BDS and MS-based media with various combinations of plant growth regulators provided gynogenic embryos. Frequencies of gynogenic plantlet development were generally low and plantlets were obtained from almost all media included in the experiments. A total of 48 gynogenic plants were produced from approximately 30 thousand immature flower buds from six donor materials included in the experiments. In the DNA amount measurements performed with flow cytometry, it was found that gynogenic A. ampeloprasum plants were mostly diploid (55.56 % and the others were tetraploid (44.44 %. Diploid and tetraploid gynogenic plants were transferred to in vivo for further evaluation and grown in a greenhouse to produce selfed seed. Our studies with leek and several other Alliums indicate that gynogenesis induction frequencies are generally low due to genotypic effect. In order to obtain sufficient numbers of gynogenic lines from leek breeding populations, high numbers of immature flowers should be cultured on gynogenesis induction media. We suggest use of large size flower buds collected several days prior to anthesis while establishing gynogenesis induction cultures in leek. BDS medium that is commonly used in onion gynogenesis studies can also be used for the production of gynogenic leek lines.

  2. Expression and antimicrobial function of beta-defensin 1 in the lower urinary tract.

    Directory of Open Access Journals (Sweden)

    Brian Becknell

    Full Text Available Beta defensins (BDs are cationic peptides with antimicrobial activity that defend epithelial surfaces including the skin, gastrointestinal, and respiratory tracts. However, BD expression and function in the urinary tract are incompletely characterized. The purpose of this study was to describe Beta Defensin-1 (BD-1 expression in the lower urinary tract, regulation by cystitis, and antimicrobial activity toward uropathogenic Escherichia coli (UPEC in vivo. Human DEFB1 and orthologous mouse Defb1 mRNA are detectable in bladder and ureter homogenates, and human BD-1 protein localizes to the urothelium. To determine the relevance of BD-1 to lower urinary tract defense in vivo, we evaluated clearance of UPEC by Defb1 knockout (Defb1(-/- mice. At 6, 18, and 48 hours following transurethral UPEC inoculation, no significant differences were observed in bacterial burden in bladders or kidneys of Defb1(-/- and wild type C57BL/6 mice. In wild type mice, bladder Defb1 mRNA levels decreased as early as two hours post-infection and reached a nadir by six hours. RT-PCR profiling of BDs identified expression of Defb3 and Defb14 mRNA in murine bladder and ureter, which encode for mBD-3 and mBD-14 protein, respectively. MBD-14 protein expression was observed in bladder urothelium following UPEC infection, and both mBD-3 and mBD-14 displayed dose-dependent bactericidal activity toward UPEC in vitro. Thus, whereas mBD-1 deficiency does not alter bladder UPEC burden in vivo, we have identified mBD-3 and mBD-14 as potential mediators of mucosal immunity in the lower urinary tract.

  3. Challenges of diagnosing and managing the adolescent with heavy menstrual bleeding.

    Science.gov (United States)

    Zia, Ayesha; Rajpurkar, Madhvi

    2016-07-01

    Unpredictable, prolonged or heavy menstrual bleeding (HMB) may be expected for many adolescents soon after menarche. A decade of clinical experience and research has now established firmly that bleeding disorders (BD) are common in adolescents with HMB. Despite these advances, many questions remain, and several aspects of the diagnosis and management of BDs in adolescents are not supported by rigorous clinical trials. In this overview, four major areas will be discussed. First, we will discuss the frequency of BDs in young women with HMB. Up to 20% of older females with HMB are thought to have an underlying BD. Estimates from retrospective studies in adolescents suggest a prevalence that varies anywhere from 10 to 62%. Prospective studies with uniform hemostatic evaluation are needed to answer this question definitively. Second, we will review existing tools that help screen and diagnose adolescents with HMB with an underlying BD. Although identification of an underlying BD in older women with HMB is relatively straight forward, uncertainties remain for adolescents. Heavy menstrual bleeding in this age group may have different pathophysiological underpinnings than those in older women and may often be disregarded as anovulatory. There is an urgent need to develop novel tools, and evaluate existing diagnostic strategies in adolescents. Third, we will discuss the optimal medical management of HMB in young adolescents. As direct evidence is largely lacking, these areas are also subject to extrapolation from older women. Lastly, an important area- prediction, and management of future bleeding in those adolescents who are diagnosed with a mild BD-will be discussed. Throughout, areas of controversy and opportunities for further research are highlighted. PMID:27208978

  4. Psychiatric Disorders and TRP Channels: Focus on Psychotropic Drugs.

    Science.gov (United States)

    Nazıroğlu, Mustafa; Demirdaş, Arif

    2015-01-01

    Psychiatric and neurological disorders are mostly associated with the changes in neural calcium ion signaling pathways required for activity-triggered cellular events. One calcium channel family is the TRP cation channel family, which contains seven subfamilies. Results of recent papers have discovered that calcium ion influx through TRP channels is important. We discuss the latest advances in calcium ion influx through TRP channels in the etiology of psychiatric disorders. Activation of TRPC4, TRPC5, and TRPV1 cation channels in the etiology of psychiatric disorders such as anxiety, fear-associated responses, and depression modulate calcium ion influx. Evidence substantiates that anandamide and its analog (methanandamide) induce an anxiolytic-like effect via CB1 receptors and TRPV1 channels. Intracellular calcium influx induced by oxidative stress has an significant role in the etiology of bipolar disorders (BDs), and studies recently reported the important role of TRP channels such as TRPC3, TRPM2, and TRPV1 in converting oxidant or nitrogen radical signaling to cytosolic calcium ion homeostasis in BDs. The TRPV1 channel also plays a function in morphine tolerance and hyperalgesia. Among psychotropic drugs, amitriptyline and capsazepine seem to have protective effects on psychiatric disorders via the TRP channels. Some drugs such as cocaine and methamphetamine also seem to have an important role in alcohol addiction and substance abuse via activation of the TRPV1 channel. Thus, we explore the relationships between the etiology of psychiatric disorders and TRP channel-regulated mechanisms. Investigation of the TRP channels in psychiatric disorders holds the promise of the development of new drug treatments. PMID:26411768

  5. An investigation of dielectric barrier discharge in Ar and Ar/NH{sub 3} mixture using cross-correlation spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Kloc, P; Trunec, D; Navratil, Z [Department of Physical Electronics, Faculty of Science, Masaryk University, Kotlarska 2, 611 37 Brno (Czech Republic); Wagner, H-E [Institute of Physics, University of Greifswald, F.-Hausdorff-Str 6., 17489 Greifswald (Germany); Fedoseev, G, E-mail: kloc@physics.muni.c [Department of Material Science, Moscow State University of Design and Technology, Sadovnicheskaya str. 33, 117997 Moscow (Russian Federation)

    2010-09-01

    Dielectric barrier discharges (BDs) are known to operate in two distinctive modes. The filamentary mode of BD is characterized by a large number of short lasting spatially bounded microdischarges. This type of discharge is typical for most cases of BDs at atmospheric pressure. Under some specific conditions another form of BD may arise. In this mode plasma uniformly covers the whole electrode area. This mode is usually referred to as the diffuse or homogeneous mode of BD. This work presents studies of the filamentary mode of BD in argon and its transition to the diffuse mode by ammonia addition. The discharges were investigated by means of cross-correlation spectroscopy. Particularly, the influence of electrode shape, discharge gap and the influence of ammonia admixture on discharge development were studied. The measurement offers results with high temporal and spatial resolution which are useful for comparison with results of numerical models. The obtained results include the electrical current measurement of discharge in several ammonia admixtures to argon. The diffuse discharge appeared at ammonia admixture above 3 vol%. The observed propagation of streamer in discharge in pure argon for two different electrode configurations is presented. When compared with discharge in pure argon the streamer velocity is decreased for 0.1 vol% ammonia admixture. With increasing ammonia concentration the streamer velocity increases again. The behaviour of presented impurities was observed and the results are included in this report. The basic model of the discharge kinetic is included. For reduced electric field below 10 Td the electron drift is much higher in argon-ammonia mixture than in pure argon.

  6. Orbit determination and prediction for Beidou GEO satellites at the time of the spring/autumn equinox

    Science.gov (United States)

    Li, XiaoJie; Zhou, JianHua; Hu, XiaoGong; Liu, Li; Guo, Rui; Zhou, ShanShi

    2015-08-01

    Geostationary (GEO) satellites form an indispensable component of the constellation of Beidou navigation system (BDS). The ephemerides, or predicted orbits of these GEO satellites(GEOs), are broadcast to positioning, navigation, and timing users. User equivalent ranging error (UERE) based on broadcast message is better than 1.5 m (root formal errors: RMS) for GEO satellites. However, monitoring of UERE indicates that the orbital prediction precision is significantly degraded when the Sun is close to the Earth's equatorial plane (or near spring or autumn Equinox). Error source analysis shows that the complicated solar radiation pressure on satellite buses and the simple box-wing model maybe the major contributor to the deterioration of orbital precision. With the aid of BDS' two-way frequency and time transfer between the GEOs and Beidou time (BDT, that is maintained at the master control station), we propose a new orbit determination strategy, namely three-step approach of the multi-satellite precise orbit determination (MPOD). Pseudo-range (carrier phase) data are transformed to geometric range (biased geometric range) data without clock offsets; and reasonable empirical acceleration parameters are estimated along with orbital elements to account for the error in solar radiation pressure modeling. Experiments with Beidou data show that using the proposed approach, the GEOs' UERE when near the autumn Equinox of 2012 can be improved to 1.3 m from 2.5 m (RMS), and the probability of user equivalent range error (UERE)<2.0 m can be improved from 50% to above 85%.

  7. Data-driven Ontology Development: A Case Study at NASA's Atmospheric Science Data Center

    Science.gov (United States)

    Hertz, J.; Huffer, E.; Kusterer, J.

    2012-12-01

    Well-founded ontologies are key to enabling transformative semantic technologies and accelerating scientific research. One example is semantically enabled search and discovery, making scientific data accessible and more understandable by accurately modeling a complex domain. The ontology creation process remains a challenge for many anxious to pursue semantic technologies. The key may be that the creation process -- whether formal, community-based, automated or semi-automated -- should encompass not only a foundational core and supplemental resources but also a focus on the purpose or mission the ontology is created to support. Are there tools or processes to de-mystify, assess or enhance the resulting ontology? We suggest that comparison and analysis of a domain-focused ontology can be made using text engineering tools for information extraction, tokenizers, named entity transducers and others. The results are analyzed to ensure the ontology reflects the core purpose of the domain's mission and that the ontology integrates and describes the supporting data in the language of the domain - how the science is analyzed and discussed among all users of the data. Commonalities and relationships among domain resources describing the Clouds and Earth's Radiant Energy (CERES) Bi-Directional Scan (BDS) datasets from NASA's Atmospheric Science Data Center are compared. The domain resources include: a formal ontology created for CERES; scientific works such as papers, conference proceedings and notes; information extracted from the datasets (i.e., header metadata); and BDS scientific documentation (Algorithm Theoretical Basis Documents, collection guides, data quality summaries and others). These resources are analyzed using the open source software General Architecture for Text Engineering, a mature framework for computational tasks involving human language.

  8. Basic characterization of avian β-defensin genes in the Japanese quail, Coturnix japonica.

    Science.gov (United States)

    Ishige, Taichiro; Hara, Hiromi; Hirano, Takashi; Mannen, Hideyuki; Kono, Tomohiro; Hanzawa, Kei

    2016-03-01

    In this study, we identified a cluster of 14 avian β-defensins (AvBD; approximately 66 kbp) in the Japanese quail, Coturnix japonica. Except for AvBD12 (CjAvBD12) and -13, the CjAvBDs coding sequences exhibited greater than 78.0% similarity to the respective orthologous chicken AvBD genes (GgAvBD). The putative amino acid sequence encoded by each CjAvBD contained six cysteine residues and the GXC (X1-2) motif considered essential for the β-defensin family. Each CjAvBDs also formed a sub-group with the respective orthologous genes of various bird species in a phylogenetic tree analysis. Synteny between the CjAvBD cluster and GgAvBD cluster was confirmed. The CjAvBD cluster was mapped on the long-arm end of chromosome 3 by linkage analysis based on single nucleotide polymorphisms (SNPs) of CjAvBD1 and CjAvBD12 (approximately 46 kbp), as well as GgAvBD cluster. We also confirmed that CjAvBD1, -4, -5, -9, and -10 are transcribed in 20 tissues, including immune and digestive tissues. However, our experimental data indicated that the CjAvBD cluster lacks the AvBD3 and -7 loci, whereas the CjAvBD101α, -101β, and -101θ loci arose from gene duplication of the AvBD6 orthologous locus in the CjAvBD cluster after differentiation between Coturnix - Gallus. PMID:26338292

  9. 多频段圆极化微带天线的设计%Design of multi-band circular polarized microstrip antenna

    Institute of Scientific and Technical Information of China (English)

    王丽黎; 刘丽珍

    2014-01-01

    A multi-band circular polarized microstrip antenna for navigation satellite system is designed. To enhance the impedance bandwidth and realize right-handed circular polarization radiation,the CRLH transmission line phase shifter is used as a feed network,which also improves performance of circular polarization at the same time. The antenna has been designed to operate at the satellite navigation frequency bands including GPS, BDS-2 and GLONASS. Ansoft HFSS 13.0 software is used, and the results of the simulation show that the antenna can meet the requirements of the signals of navigation satellite system. The antenna has the characteristics of the compact, frequency bandwidth, small size, easy processing.%设计了一款应用于导航卫星系统的多频段圆极化微带天线。天线采用复合左右手传输线移相器作为馈电网络,展宽阻抗带宽并且实现了良好的右旋圆极化辐射。该天线工作在导航卫星系统GPS、BDS-2和 GLONASS 工作波段。采用 Ansoft HFSS 13.0软件仿真,仿真结果表明该天线能够满足导航卫星信号的要求。该天线具有结构紧凑、频带宽、体积小、易于加工等特点。

  10. [Current modalities and concepts on access and use of biospecimen samples and associated data for research from human biobanks].

    Science.gov (United States)

    Siddiqui, Roman; Semler, Sebastian Claudius

    2016-03-01

    It is accepted worldwide that biospecimen and data sharing (BDS) play an essential role for the future of medical research to improve diagnostics and prognostics, e.g. by validated biomarkers. BDS is also pivotal to the development of new therapeutic treatments and for the improvement of population health. Human biobanks can generate an added value to this need by providing biospecimens and/or associated data to researchers. An inspection of several examples of epidemiological as well as clinical/disease-oriented biobanks in Germany shows that best practice procedures (BPP) that are internationally agreed on are being installed for biospecimen and/or data access. In general, fair access is aimed at requiring a written application by the requesting scientist, which is then peer-reviewed for scientific and ethical validity by the Biobank. Applied BPP take into account (i) patient education/agreement according to the informed consent model, (ii) privacy protection, (iii) intellectual property rights, the (iv) notification obligation of health-related findings (including incidental findings), the (v) use of material (MTA) and data transfer agreements (DTA) for mutual legal security, the avoidance of conflicts of interests, as well as for cost recovery/fee for service as a basis for sustainability of the biobank. BPP are rooted in the self-regulation efforts of life sciences and are supported by parent ethics committees in Germany. Central biobank registries displaying aggregated information on biospecimens stored and the research foci constitute an important tool to make biobanks that are scattered across the country visible to each other, and, can thus promote access to hitherto unknown biospecimen and data resources. PMID:26809822

  11. Preliminary validation of the refractivity from the new radio occultation sounder GNOS/FY-3C

    Science.gov (United States)

    Liao, Mi; Zhang, Peng; Yang, Guang-Lin; Bi, Yan-Meng; Liu, Yan; Bai, Wei-Hua; Meng, Xiang-Guang; Du, Qi-Fei; Sun, Yue-Qiang

    2016-03-01

    As a new member of the space-based radio occultation sounders, the GNOS (Global Navigation Satellite System Occultation Sounder) mounted on Fengyun-3C (FY-3C) has been carrying out atmospheric sounding since 23 September 2013. GNOS takes approximately 800 daily measurements using GPS (Global Positioning System) and Chinese BDS (BeiDou navigation satellite) signals. In this work, the atmospheric refractivity profiles from GNOS were compared with the ones obtained from the co-located ECMWF (European Centre for Medium-Range Weather Forecasts) reanalysis. The mean bias of the refractivity obtained through GNOS GPS (BDS) was found to be approximately -0.09 % (-0.04 %) from the near surface to up to 46 km. While the average standard deviation was approximately 1.81 % (1.26 %), it was as low as 0.75 % (0.53 %) in the range of 5-25 km, where best sounding results are usually achieved. Further, COSMIC (Constellation Observing System for Meteorology, Ionosphere and Climate) and MetOp/ GRAS (GNSS Receiver for Atmospheric Sounding) radio occultation data were compared with the ECMWF reanalysis; the results thus obtained could be used as reference data for GNOS. Our results showed that GNOS/FY-3C meets the design requirements in terms of accuracy and precision of the sounder. It possesses a sounding capability similar to COSMIC and MetOp/GRAS in the vertical range of 0-30 km, though it needs further improvement above 30 km. Overall, it provides a new data source for the global numerical weather prediction (NWP) community.

  12. Deformation effects on sub-barrier fusion cross sections in 16O+174,176Yb

    Science.gov (United States)

    Rajbongshi, Tapan; Kalita, K.; Nath, S.; Gehlot, J.; Banerjee, Tathagata; Mukul, Ish; Dubey, R.; Madhavan, N.; Lin, C. J.; Shamlath, A.; Laveen, P. V.; Shareef, M.; Kumar, Neeraj; Jisha, P.; Sharma, P.

    2016-05-01

    Background: Couplings with various reaction channels are known to enhance sub-barrier fusion cross sections by several orders in magnitude. However, a few open questions still remain. For example, the influence of higher order static deformations on sub-barrier fusion cross sections is yet to be comprehensively understood. Purpose: We study the role of hexadecapole nuclear deformation effect on sub-barrier fusion cross sections. Also, this work aims to extract hexadecapole deformation (β4) in nuclei in the lanthanide region. Method: The evaporation residue (ER) excitation functions for 16O+174,176Yb were measured at laboratory beam energies (Elab) in the range of 64.6-103.6 MeV. Measurements were carried out by employing the recoil mass spectrometer Heavy Ion Reaction Analyzer (HIRA) at IUAC, New Delhi. Fusion barrier distributions (BDs) were extracted from data. Results from the experiment were subjected to coupled-channels analysis, in which β4 was varied as a free parameter. Results: Experimental fusion cross sections at energies below the barrier expectedly showed strong enhancement compared to the predictions from the one-dimensional barrier penetration model. Data were satisfactorily reproduced after inclusion of negative β4 for both the targets in the coupled-channels calculation. Conclusions: The significant role of hexadecapole deformation was observed in the sub-barrier fusion of 16O+174,176Yb. The proposed value of β4 reproduced the measured fusion excitation function reasonably well. The BDs from these data were also extracted but no definitive conclusions could be drawn from them.

  13. A modified EPA Method 1623 that uses tangential flow hollow-fiber ultrafiltration and heat dissociation steps to detect waterborne Cryptosporidium and Giardia spp.

    Science.gov (United States)

    Rhodes, Eric R; Villegas, Leah Fohl; Shaw, Nancy J; Miller, Carrie; Villegas, Eric N

    2012-01-01

    Cryptosporidium and Giardia species are two of the most prevalent protozoa that cause waterborne diarrheal disease outbreaks worldwide. To better characterize the prevalence of these pathogens, EPA Method 1623 was developed and used to monitor levels of these organisms in US drinking water supplies (12). The method has three main parts; the first is the sample concentration in which at least 10 L of raw surface water is filtered. The organisms and trapped debris are then eluted from the filter and centrifuged to further concentrate the sample. The second part of the method uses an immunomagnetic separation procedure where the concentrated water sample is applied to immunomagnetic beads that specifically bind to the Cryptosporidium oocysts and Giardia cysts allowing for specific removal of the parasites from the concentrated debris. These (oo)cysts are then detached from the magnetic beads by an acid dissociation procedure. The final part of the method is the immunofluorescence staining and enumeration where (oo)cysts are applied to a slide, stained, and enumerated by microscopy. Method 1623 has four listed sample concentration systems to capture Cryptosporidium oocysts and Giardia cysts in water: Envirochek filters (Pall Corporation, Ann Arbor, MI), Envirochek HV filters (Pall Corporation), Filta-Max filters (IDEXX, Westbrook, MA), or Continuous Flow Centrifugation (Haemonetics, Braintree, MA). However, Cryptosporidium and Giardia (oo)cyst recoveries have varied greatly depending on the source water matrix and filters used(1,14). A new tangential flow hollow-fiber ultrafiltration (HFUF) system has recently been shown to be more efficient and more robust at recovering Cryptosporidium oocysts and Giardia cysts from various water matrices; moreover, it is less expensive than other capsule filter options and can concentrate multiple pathogens simultaneously(1-3,5-8,10,11). In addition, previous studies by Hill and colleagues demonstrated that the HFUF significantly

  14. High-Performance Palladium Based Membrane for Hydrogen Separation and Purification

    Energy Technology Data Exchange (ETDEWEB)

    Hopkins, Scott

    2012-01-31

    The mission of the DOE's Fuel Cell Technologies'Hydrogen Fuels R&D effort is to research, develop, and validate technologies for producing, storing, and delivering hydrogen in an efficient, clean, safe, reliable, and affordable manner. A key program technical milestone for hydrogen technology readiness is to produce hydrogen from diverse, domestic resources at $2.00-$3.00 per gallon of gasoline equivalent (gge) delivered, untaxed. Low-cost, high-temperature hydrogen separation membranes represent a key enabling technology for small-scale distributed hydrogen production units. Availability of such membranes with high selectivity and high permeability for hydrogen will allow their integration with hydrocarbon reforming and water gas shift reactions, potentially reducing the cost of hydrogen produced. Pd-metal-based dense membranes are known for their excellent hydrogen selectivity and permeability characteristics, however, utilization of these membranes has so far been limited to small scale niche markets for hydrogen purification primarily due to the relatively high cost of Pd-alloy tubes compared to pressure swing adsorption (PSA) units. This project was aimed at development of thin-film Pd-alloy membranes deposited on Pall Corporation's DOE-based AccuSep® porous metal tube substrates to form a composite hydrogen separation membrane for these applications. Pall's composite membrane development addressed the typical limitations of composite structures by developing robust membranes capable of withstanding thermal and mechanical stresses resulting from high temperature (400C), high pressure (400 psi steam methane reformer and 1000 psi coal) operations and thermal cycling involved in conventional hydrogen production. In addition, the Pd-alloy membrane composition was optimized to be able to offer the most stability in the typical synthesis gas environments produced by reforming of natural gas and bio-derived liquid fuels (BILI) validating the

  15. Decontamination of wastewater containing persistent toxic compounds by combining solar photo catalysis and biological oxidation; Depuracion de aguas contaminadas con toxicos persistentes mediante combinacion de fotocatalisis solar y oxidacion biologica

    Energy Technology Data Exchange (ETDEWEB)

    Oller Alverola, I.; Sanchez Perez, J. A.; Malato Rodriguez, S.

    2008-07-01

    in the photo-Fenton process at which toxicity had gone down. The biological reactor used in this research is a fixed-bed reactor colonized by WWTP activated sludge fixed on polypropylene PallRing supports. The combination of the photo-Fenton and biological reactor treatment of the pesticides was successful, both in batch and continuous modes, achieving a maximum treatment capacity of 16 mg COD/h L Pall Ring (overall efficiency over 90%). In a later stage of research, this methodology for combining photo-Fenton and aerobic biological degradation was successfully applied to treatment of industrial saline waste water from a pharmaceutical plant. (Author)

  16. Particulate hot gas stream cleanup technical issues

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-09-01

    This is the eleventh in a series of quarterly reports describing the activities performed under Contract No. DE-AC21-94MC31160. Analyses of Hot Gas Stream Cleanup (HGCU) ashes and descriptions of filter performance address aspects of filter operation that are apparently linked to the characteristics of the collected ash or the performance of the ceramic bed filter elements. Task 1 is designed to generate a data base of the key characteristics of ashes collected from operating advanced particle filters (APFS) and to relate these ash properties to the operation and performance of these filters. Task 2 concerns testing and failure analysis of ceramic filter elements. Under Task 1 during the past quarter, analyses were completed on samples obtained during a site visit to the Power Systems Development Facility (PSDF). Analyses are in progress on ash samples from the Advanced Particulate Filter (APF) at the Pressurized Fluidized-Bed Combustor (PFBC) that was in operation at Tidd and ash samples from the Pressurized Circulating Fluid Bed (PCFB) system located at Karhula, Finland. An additional analysis was performed on a particulate sample from the Transport Reactor Demonstration Unit (TRDU) located at the University of North Dakota Energy and Environmental Research Center. A manuscript and poster were prepared for presentation at the Advanced Coal-Based Power and Environmental Systems `97 Conference scheduled for July 22 - 24, 1997. A summary of recent project work covering the mechanisms responsible for ash deposit consolidation and ash bridging in APF`s collecting PFB ash was prepared and presented at FETC-MGN in early July. The material presented at that meeting is included in the manuscript prepared for the Contractor`s Conference and also in this report. Task 2 work during the past quarter included mechanical testing and microstructural examination of Schumacher FT20 and Pall 326 as- manufactured, after 540 hr in service at Karhula, and after 1166 hr in service at

  17. Evaluation of Alternative Filter Media for the Rotary Microfilter

    International Nuclear Information System (INIS)

    The Savannah River Site is currently developing and testing several processes to treat high level radioactive liquid waste. Each of these processes has a solid-liquid separation process that limits its throughput. Savannah River National Laboratory researchers identified and tested the rotary microfilter as a technology to increase solid-liquid separation throughput. The authors believe the rotary microfilter throughput can be improved by using a better filter membrane. Previous testing showed that asymmetric filters composed of a ceramic membrane on top of a stainless steel support produced higher filter flux than 100% stainless steel symmetric filters in crossflow filter tests. Savannah River National Laboratory and Oak Ridge National Laboratory are working together to develop asymmetric ceramic-stainless steel composite filters and asymmetric 100% stainless steel filters to improve the throughput of the rotary microfilter. The Oak Ridge National Laboratory Inorganic Membrane Group fabricated samples of alternative filter membranes. In addition, Savannah River National Laboratory obtained samples of filter membranes from Pall, Porvair, and SpinTek. They tested these samples in a static test cell with feed slurries containing monosodium titanate and simulated sludge

  18. Quantitative Proteomics Analysis of Herbaceous Peony in Response to Paclobutrazol Inhibition of Lateral Branching

    Directory of Open Access Journals (Sweden)

    Daqiu Zhao

    2015-10-01

    Full Text Available Herbaceous peony (Paeonia lactiflora Pall. is an emerging high-grade cut flower worldwide, which is usually used in wedding bouquets and known as the “wedding flower”. However, abundant lateral branches appear frequently in some excellent cultivars, and a lack of a method to remove Paeonia lactiflora lateral branches other than inefficient artificial methods is an obstacle for improving the quality of its cut flowers. In this study, paclobutrazol (PBZ application was found to inhibit the growth of lateral branches in Paeonia lactiflora for the first time, including 96.82% decreased lateral bud number per branch, 77.79% and 42.31% decreased length and diameter of lateral branches, respectively, declined cell wall materials and changed microstructures. Subsequently, isobaric tag for relative and absolute quantitation (iTRAQ technology was used for quantitative proteomics analysis of lateral branches under PBZ application and control. The results indicated that 178 differentially expressed proteins (DEPs successfully obtained, 98 DEPs were up-regulated and 80 DEPs were down-regulated. Thereafter, 34 candidate DEPs associated with the inhibited growth of lateral branches were screened according to their function and classification. These PBZ-stress responsive candidate DEPs were involved in eight biological processes, which played a very important role in the growth and development of lateral branches together with the response to PBZ stress. These results provide a better understanding of the molecular theoretical basis for removing Paeonia lactiflora lateral branches using PBZ application.

  19. Danggui-Shaoyao-San: New Hope for Alzheimer's Disease.

    Science.gov (United States)

    Fu, Xin; Wang, QiuHong; Wang, ZhiBin; Kuang, HaiXue; Jiang, Pinghui

    2016-08-01

    Danggui-Shaoyao-San (DSS), also called Toki-shakuyaku-san (TJ-23) or Dangguijakyak-san (DJS), is a well-known herbal formula (Angelica sinensis (Oliv.) Diels., Ligusticum chuanxiong Hort., Paeonia lactiflora pall., Poria cocos (Schw.) Wolf, Alisma orientalis (Sam.) Juzep., Atractylodes macrocephala Koidz.), which has been widely used in oriental countries for the treatment of various gynecological diseases. Recent studies show that DSS has an effect on free radical-mediated neurological diseases and exhibits anti-inflammatory and antioxidant activities and reduces cell apoptosis in the hippocampus. In addition, DSS mediates the modulation of central monoamine neurotransmitter systems and ameliorates dysfunction of the central cholinergic nervous system and scopolamine-induced decrease in ACh levels. DSS improves the function of the dopaminergic, adrenergic, and serotonergic nervous systems. Interestingly, DSS can alleviate cognitive dysfunction of Alzheimer's disease (AD) patients, suggesting that it is a useful therapeutic agent for AD. This paper reviews the mechanism of DSS for the treatment of AD. PMID:27493835

  20. The Effects of Refraction on Transit Transmission Spectroscopy: Application to Earth-like Exoplanets

    CERN Document Server

    Misra, Amit; Crisp, Dave

    2014-01-01

    We quantify the effects of refraction in transit transmission spectroscopy on spectral absorption features and on temporal variations that could be used to obtain altitude-dependent spectra for planets orbiting stars of different stellar types. We validate our model against altitude-dependent transmission spectra of the Earth from ATMOS and against lunar eclipse spectra from Palle et al. (2009). We perform detectability studies to show the potential effects of refraction on hypothetical observations of Earth analogs with the James Webb Space Telescope (JWST) Near-Infrared Spectrograph (NIRSPEC). Due to refraction, there will be a maximum tangent pressure level that can be probed during transit for each given planet-star system. We show that because of refraction, for an Earth-analog planet orbiting in the habitable zone of a Sun-like star only the top 0.3 bars of the atmosphere can be probed, leading to a decrease in the signal to noise ratio (SNR) of absorption features by 60%, while for an Earth-analog plan...

  1. Evaluation of Alternative Filter Media for the Rotary Microfilter

    Energy Technology Data Exchange (ETDEWEB)

    Poirier, M. R.; Herman, D. T.; Bhave, R.

    2011-11-09

    The Savannah River Site is currently developing and testing several processes to treat high level radioactive liquid waste. Each of these processes has a solid-liquid separation process that limits its throughput. Savannah River National Laboratory researchers identified and tested the rotary microfilter as a technology to increase solid-liquid separation throughput. The authors believe the rotary microfilter throughput can be improved by using a better filter membrane. Previous testing showed that asymmetric filters composed of a ceramic membrane on top of a stainless steel support produced higher filter flux than 100% stainless steel symmetric filters in crossflow filter tests. Savannah River National Laboratory and Oak Ridge National Laboratory are working together to develop asymmetric ceramic ? stainless steel composite filters and asymmetric 100% stainless steel filters to improve the throughput of the rotary microfilter. The Oak Ridge National Laboratory Inorganic Membrane Group fabricated samples of alternative filter membranes. In addition, Savannah River National Laboratory obtained samples of filter membranes from Pall, Porvair, and SpinTek. They tested these samples in a static test cell with feed slurries containing monosodium titanate and simulated sludge.

  2. Theoretical considerations about a membrane process for helium purification in multichannel monoliths for high temperature nuclear reactors

    International Nuclear Information System (INIS)

    Highlights: ► Modeling and simulation of helium purification in HTR. ► Membrane separation process for helium purification. ► Microporous silica membrane on multichannel monolith support. ► Effect of thick porous support on gas separation process. ► New cascade configuration of membrane modules for optimized purification. - Abstract: In this work we present the modeling and simulation of a new membrane process for helium purification in high temperature nuclear reactors. We considered the application of multichannel porous monolith supports from Pall-Exekia, with thin, microporous layers of silica/alumina. These membranes present helium permeance values in the range of 10−10 kmol m−2 s−1 Pa−1 at 300 °C for transmembrane pressures of 1–60 bar. The Dusty Gas Model was used in order to highlight the effect of the porous support on the separation. An original new cascade configuration has been designed to reach the desired range of helium purity. Simulations showed many advantages of this configuration over those previously reported in the bibliography because there are no recycles and no intermediate compression units.

  3. Efficacy of Rodent Control in Alfalfa and Wheat Crops Using Chemical and Natural Rodenticides

    Directory of Open Access Journals (Sweden)

    Suzana Đedović

    2007-01-01

    Full Text Available Biological efficacy of chemical and natural rodenticides in controlling rodents in alfalfa and wheat crops was investigated. The experiment was set up using a randomized block design with four replicates and 400 m2 plots in compliace with a standard OEPP/EPPO method. Examination was based on the average number of active holes and rodenticide efficacy was measured three, seven, 14 and 28 days after treatment. Rodent numbers were computed from the number of active holes, and rodenticide efficacy using Abbott’s formula.The appearance and arrangement of active holes indicated the presence of common vole (Microtus arvalis Pall and striped field mouse (Apodemus agrarius in the plots. The products tested demonstrated satisfactory efficacy in controlling rodents in alfalfa and wheatcrops. Products based on vitamin D3 achieved 87-90% efficacy in both crops. The efficacy of a bromadiolone-based product ranged from 84% to 90%, while a cellulose product displayed the highest variation in efficacy, ranging from 86% to 98%.

  4. Plant uptake and transport of 241Am

    International Nuclear Information System (INIS)

    We conducted several experiments with 241Am to obtain a more complete understanding of how this transuranium element is absorbed and transported in plants. In a plant species (Tamarix pentandra Pall.) that has salt glands in the leaves excreting NaCl and other ions, 241Am was not pumped through these glands. Cyanide, which forms complexes with any metals, when applied to a calcareous soil, greatly increased the transport of 241Am into stems and leaves of bush bean plants. Radioactive cyanide (14C) was also transported to leaves and stems. When radish was grown in both calcareous and noncalcareous soils, 241Am appeared to be fixed on the peel so firmly that it was resistant to removal by HNO3 washing. The chelating agent DTPA induced increased transport of 241Am to leaves and into the fleshy roots of the radish. Data for Golden Cross hybrid corn grown in solution culture showed at least seven times as much 241Am transport to the xylem exudatields are corrected by recovery of added tracers

  5. Identification of 1,2,3,4,6-Penta-O-galloyl-β-d-glucopyranoside as a Glycine N-Methyltransferase Enhancer by High-Throughput Screening of Natural Products Inhibits Hepatocellular Carcinoma.

    Science.gov (United States)

    Kant, Rajni; Yen, Chia-Hung; Lu, Chung-Kuang; Lin, Ying-Chi; Li, Jih-Heng; Chen, Yi-Ming Arthur

    2016-01-01

    Glycine N-methyltransferase (GNMT) expression is vastly downregulated in hepatocellular carcinomas (HCC). High rates of GNMT knockout mice developed HCC, while overexpression of GNMT prevented aflatoxin-induced carcinogenicity and inhibited liver cancer cell proliferation. Therefore, in this study, we aimed for the identification of a GNMT inducer for HCC therapy. We established a GNMT promoter-driven luciferase reporter assay as a drug screening platform. Screening of 324 pure compounds and 480 crude extracts from Chinese medicinal herbs resulted in the identification of Paeonia lactiflora Pall (PL) extract and the active component 1,2,3,4,6-penta-O-galloyl-β-d-glucopyranoside (PGG) as a GNMT inducer. Purified PL extract and PGG induced GNMT mRNA and protein expression in Huh7 human hepatoma cells and in xenograft tumors. PGG and PL extract had potent anti-HCC effects both in vitro and in vivo. Furthermore, PGG treatment induced apoptosis in Huh7 cells. Moreover, PGG treatment sensitized Huh7 cells to sorafenib treatment. Therefore, these results indicated that identifying a GNMT enhancer using the GNMT promoter-based assay might be a useful approach to find drugs for HCC. These data also suggested that PGG has therapeutic potential for the treatment of HCC. PMID:27153064

  6. Identification of 1,2,3,4,6-Penta-O-galloyl-β-d-glucopyranoside as a Glycine N-Methyltransferase Enhancer by High-Throughput Screening of Natural Products Inhibits Hepatocellular Carcinoma

    Directory of Open Access Journals (Sweden)

    Rajni Kant

    2016-05-01

    Full Text Available Glycine N-methyltransferase (GNMT expression is vastly downregulated in hepatocellular carcinomas (HCC. High rates of GNMT knockout mice developed HCC, while overexpression of GNMT prevented aflatoxin-induced carcinogenicity and inhibited liver cancer cell proliferation. Therefore, in this study, we aimed for the identification of a GNMT inducer for HCC therapy. We established a GNMT promoter-driven luciferase reporter assay as a drug screening platform. Screening of 324 pure compounds and 480 crude extracts from Chinese medicinal herbs resulted in the identification of Paeonia lactiflora Pall (PL extract and the active component 1,2,3,4,6-penta-O-galloyl-β-d-glucopyranoside (PGG as a GNMT inducer. Purified PL extract and PGG induced GNMT mRNA and protein expression in Huh7 human hepatoma cells and in xenograft tumors. PGG and PL extract had potent anti-HCC effects both in vitro and in vivo. Furthermore, PGG treatment induced apoptosis in Huh7 cells. Moreover, PGG treatment sensitized Huh7 cells to sorafenib treatment. Therefore, these results indicated that identifying a GNMT enhancer using the GNMT promoter-based assay might be a useful approach to find drugs for HCC. These data also suggested that PGG has therapeutic potential for the treatment of HCC.

  7. Comparison of Paeoniflorin and Albiflorin on Human CYP3A4 and CYP2D6

    Directory of Open Access Journals (Sweden)

    Li-Na Gao

    2015-01-01

    Full Text Available Peony (Paeonia lactiflora Pall- is a plant medicine and a functional food ingredient with wide application for more than 2000 years. It can be coadministrated with many other drugs, composed of traditional Chinese medicine compound such as shaoyao-gancao decoction. In order to explore the efficacy and safety of peony, effects of paeoniflorin and albiflorin (the principal components of peony on cytochrome P450 (CYP 3A4 and CYP2D6 were analyzed in human hepatoma HepG2 cells and evaluated from the level of recombinant CYP enzymes in vitro. The findings indicated that albiflorin possessed stronger regulation on the mRNA expression of CYP3A4 and CYP2D6 than paeoniflorin. For the protein level of CYP3A4, albiflorin showed significant induction or inhibition with the concentration increasing from 10−7 M to 10−5 M, but no remarkable variation was observed in paeoniflorin-treated group. Enzyme activity assay implied that both paeoniflorin and albiflorin could regulate CYP3A4 and CYP2D6 with varying degrees. The results showed that albiflorin should be given more attention because it may play a vital role on the overall efficacy of peony. The whole behavior of both paeoniflorin and albiflorin should be focused on ensuring the rationality and effectiveness of clinical application.

  8. Soil carbon sequestration by three perennial legume pastures is greater in deeper soil layers than in the surface soil

    Science.gov (United States)

    Guan, X.-K.; Turner, N. C.; Song, L.; Gu, Y.-J.; Wang, T.-C.; Li, F.-M.

    2016-01-01

    Soil organic carbon (SOC) plays a vital role as both a sink for and source of atmospheric carbon. Revegetation of degraded arable land in China is expected to increase soil carbon sequestration, but the role of perennial legumes on soil carbon stocks in semiarid areas has not been quantified. In this study, we assessed the effect of alfalfa (Medicago sativa L.) and two locally adapted forage legumes, bush clover (Lespedeza davurica S.) and milk vetch (Astragalus adsurgens Pall.) on the SOC concentration and SOC stock accumulated annually over a 2 m soil profile. The results showed that the concentration of SOC in the bare soil decreased slightly over the 7 years, while 7 years of legume growth substantially increased the concentration of SOC over the 0-2.0 m soil depth. Over the 7-year growth period the SOC stocks increased by 24.1, 19.9 and 14.6 Mg C ha-1 under the alfalfa, bush clover and milk vetch stands, respectively, and decreased by 4.2 Mg C ha-1 in the bare soil. The sequestration of SOC in the 1-2 m depth of the soil accounted for 79, 68 and 74 % of the SOC sequestered in the 2 m deep soil profile under alfalfa, bush clover and milk vetch, respectively. Conversion of arable land to perennial legume pasture resulted in a significant increase in SOC, particularly at soil depths below 1 m.

  9. Podavač palet svislého obráběcího centra.

    OpenAIRE

    Krenželok, Andrzej

    2010-01-01

    Předmětem této diplomové práce je návrh konstrukčního řešení přenašeče palet svislého obráběcího centra. Přenašeč slouží k manipulaci s technologickými paletami mezi odkládacími místy obráběcích center a zásobníkem palet. Díky tomuto přenašeči stroje sdílejí jednu obrobkovou základnu. Hlavní důraz je kladen nejen na funkčnost, ale také na nízkou cenu řešení. The subject of this thesis is the proposal of constructional solution for pallet changer of the vertical machining center. This palle...

  10. Laboratory and Simulated Field Bioassays to Evaluate Larvicidal Activity of Pinus densiflora Hydrodistillate, Its Constituents and Structurally Related Compounds against Aedes albopictus, Aedes aegypti and Culex pipiens pallens in Relation to Their Inhibitory Effects on Acetylcholinesterase Activity.

    Science.gov (United States)

    Lee, Dong Chan; Ahn, Young-Joon

    2013-01-01

    The toxicity of Pinus densiflora (red pine) hydrodistillate, its 19 constituents and 28 structurally related compounds against early third-instar larvae of Aedes albopictus (Ae. albopictus), Aedes aegypti (Ae. aegypti) and Culex pipiens palles (Cx. p. pallens) was examined using direct-contact bioassays. The efficacy of active compounds was further evaluated in semi-field bioassays using field-collected larval Cx. p. pallens. Results were compared with those of two synthetic larvicides, temephos and fenthion. In laboratory bioassays, Pinus densiflora hydrodistillate was found to have 24 h LC50 values of 20.33, 21.01 and 22.36 mg/L against larval Ae. albopictus, Ae. aegypti and Cx. p. pallens respectively. Among the identified compounds, thymol, δ-3-carene and (+)-limonene exhibited the highest toxicity against all three mosquito species. These active compounds were found to be nearly equally effective in field trials as well. In vitro bioassays were conducted to examine the acetylcholinesterase (AChE) inhibitory activity of 10 selected compounds. Results showed that there is a noticeable correlation between larvicidal activity and AChE inhibitory activity. In light of global efforts to find alternatives for currently used insecticides against disease vector mosquitoes, Pinus densiflora hydrodistillate and its constituents merit further research as potential mosquito larvicides. PMID:26464387

  11. Laboratory and Simulated Field Bioassays to Evaluate Larvicidal Activity of Pinus densiflora Hydrodistillate, Its Constituents and Structurally Related Compounds against Aedes albopictus, Aedes aegypti and Culex pipiens pallens in Relation to Their Inhibitory Effects on Acetylcholinesterase Activity

    Directory of Open Access Journals (Sweden)

    Young-Joon Ahn

    2013-05-01

    Full Text Available The toxicity of Pinus densiflora (red pine hydrodistillate, its 19 constituents and 28 structurally related compounds against early third-instar larvae of Aedes albopictus (Ae. albopictus, Aedes aegypti (Ae. aegypti and Culex pipiens palles (Cx. p. pallens was examined using direct-contact bioassays. The efficacy of active compounds was further evaluated in semi-field bioassays using field-collected larval Cx. p. pallens. Results were compared with those of two synthetic larvicides, temephos and fenthion. In laboratory bioassays, Pinus densiflora hydrodistillate was found to have 24 h LC50 values of 20.33, 21.01 and 22.36 mg/L against larval Ae. albopictus, Ae. aegypti and Cx. p. pallens respectively. Among the identified compounds, thymol, δ-3-carene and (+-limonene exhibited the highest toxicity against all three mosquito species. These active compounds were found to be nearly equally effective in field trials as well. In vitro bioassays were conducted to examine the acetylcholinesterase (AChE inhibitory activity of 10 selected compounds. Results showed that there is a noticeable correlation between larvicidal activity and AChE inhibitory activity. In light of global efforts to find alternatives for currently used insecticides against disease vector mosquitoes, Pinus densiflora hydrodistillate and its constituents merit further research as potential mosquito larvicides.

  12. Cloning of vacuolar H+-ATPase subunit c genes from Japanese iris, and functional characterization in yeast

    Institute of Scientific and Technical Information of China (English)

    ZHOU Ai-min; WU Duo; CHE Dai-di; LIU Shen-kui; YANG Chuan-ping; WANG Jin-gang

    2011-01-01

    Five different isoforms (IrlVHA-cl-c5) of V-ATPase subunit c(VHA-c) were cloned from a Japanese iris (Iris lactea Pall. Var. chinensisFisch. Koidz) cDNA library using degenerate primers PCR and the5'-RACE technique. The sequence analysis showed the open readingframe (ORF) of the IrlVHA-c1-c5 to be 495 bp, corresponding to a pro-tein of 164 amino acids. Among the five isoforms, IrlVHA-c1 andIrlVHA-c2 are completely homologous. The IrlVHA-c protein is localizedat the vacuolar membrane as indicated by a green fluorescent protein(GFP) marker. Its over-expression in yeast could enhance yeast toleranceto NaCl stress. These results show that there are at least five genes en-coding different isoforms of IrlVHA-c in Japanese iris and IrlVHA-c isimportant for the function of V-ATPase.

  13. [Use of leukocyte-filtered, cytomegalovirus-antibody negative and irradiated cellular blood products].

    Science.gov (United States)

    Solheim, B G; Albrechtsen, D H; Evensen, S A; Leivestad, T

    1990-01-10

    This paper presents both quality requirements and indications for use of leucocyte-filtered, cytomegalovirus antibody negative and irradiated cellular blood products at Rikshospitalet. Emphasis is placed on the use of standardized buffycoat depleted red cells or platelet concentrates for filtration, and the selection of leucocyte filters with high capacity and ease of bedside application. Leucocyte counts as low as 1-2 10(5) per unit are recommended after filtration in order to avoid HLA-antibody production. For bedside filtration, our choice was RC100 and PL100 (Pall) for red cells and platelets respectively. For laboratory use we prefer, for economic reasons, to use Sepacell R500 (Asahi) and Imugard IG500 (Terumo) for red cells and platelets respectively. Leucocyte-filtered blood products are considered indicated in all pre-transplant transfusions, in post-transplant HLA-sensitized patients, in other patients with febrile transfusion reactions, and in patients with an expected protracted platelet requirement. CMV antibody negative products are recommended for all immuno-deficient patients and pregnant women negative for CMV antibody. Irradiated blood products are used in the treatment of immuno-deficient patients receiving large amounts of blood, and in all severely immuno-compromised patients. In emergency situations where CMV antibody negative and/or irradiated blood products cannot be supplied, leucocyte filtration is suggested. PMID:2154061

  14. Effects of Seedbed Density on Seedling Morphological Characteristics of four Broadleaved Species

    Energy Technology Data Exchange (ETDEWEB)

    Yucedag, C.; Gailing, O.

    2012-11-01

    The aim of this study was to investigate the effects of seedling spacing on morphological characteristics of one year-old Amygdalus communis L., Prunus avium L., Pyrus elaeagnifolia Pall. and Eriolobus trilobatus (Poiret) Roemer seedlings under nursery conditions. Seedlings were grown in completely randomized blocks with four replications. Seedbeds were 1.2 m wide with 5 rows each 20 cm apart. Within-row spacings were chosen as 4, 8 and 12 cm to analyze the effect of seedlings density on growth performance. Seedling spacing significantly affected root collar diameter, shoot height, tap root length and number of fine roots in A. communis and P. avium, but not in P. elaeagnifolia and E. tribolatus. Additionally wider seedling spacings resulted in larger seedlings in A. communis and P. avium. In conclusion, it would be beneficial to use wider seedling spacing in order to obtain better seedling growth in A. communis and P. avium. Larger seedlings could also provide significant advantages because of reduced cultural activities and an expected higher growth and survival rate. (Author) 27 refs.

  15. Validation testing of radioactive waste drum filter vents

    Energy Technology Data Exchange (ETDEWEB)

    Weber, L.D. [Pall Corp., Port Washington, NY (United States); Rahimi, R.S. [Pall Corp., Cortland, NY (United States); Edling, D. [Edling & Associates, Inc., Russel Springs, KY (United States)

    1997-08-01

    The minimum requirements for Drum Filter Vents (DFVs) can be met by demonstrating conformance with the Waste Isolation Pilot Plant (WIPP) Trupact II Safety Assessment Report (SAR), and conformance with U.S. Federal shipping regulations 49 CFR 178.350, DOT Spec 7A, for Type A packages. These together address a number of safety related performance parameters such as hydrogen diffusivity, flow related pressure drop, filtration efficiency and, separately, mechanical stability and the ability to prevent liquid water in-leakage. In order to make all metal DFV technology (including metallic filter medium) available to DOE sites, Pall launched a product development program to validate an all metal design to meet these requirements. Numerous problems experienced by DOE sites in the past came to light during this development program. They led us to explore enhancements to DFV design and performance testing addressing these difficulties and concerns. The result is a patented all metal DFV certified to all applicable regulatory requirements, which for the first time solves operational and health safety problems reported by DOE site personnel but not addressed by previous DFV`s. The new technology facilitates operations (such as manual, automated and semi-automated drum handling/redrumming), sampling, on-site storage, and shipping. At the same time, it upgrades filtration efficiency in configurations documented to maintain filter efficiency following mechanical stress. 2 refs., 2 figs., 10 tabs.

  16. Analysis of flavonoids by capillary zone electrophoresis with electrokinetic supercharging.

    Science.gov (United States)

    Zhong, Hao; Yao, Qingqiang; Breadmore, Michael C; Li, Yumei; Lu, Yuanqi

    2011-11-01

    On-line concentration via Electrokinetic Supercharging (EKS) was used to enhance the sensitivity of the capillary electrophoretic separation of the four flavonoids naringenin, hesperetin, naringin and hesperidin. Separation conditions, including the background electrolyte pH and concentration, the length and choice of terminator and the electrokinetic injection time were optimized. The optimum conditions were: a background electrolyte of 30 mM sodium tetraborate (pH 9.5) containing 5% (v/v) of methanol, electrokinetic injection of the sample (130 s, -10 kV) followed by hydrodynamic injecting of 100 mM 2-(cyclohexylamino)ethanesulfonic acid (CHES) (17 s, 0.5 psi) as terminator, and separation with -20 kV. Under these conditions the four flavonoids could be separated with a sample-to-sample time of 15 min and detection limits from 2.0 to 6.8 ng mL(-1). When compared to a conventional hydrodynamic injection the sensitivity was enhanced between 824 and 1515 times which is 7.6-16 times higher than other CE methods for the on-line concentration of flavonoids. The applicability of the developed method was demonstrated by the detection of the four flavonoids in an aqueous extract of Clematis hexapetala pall. PMID:21949941

  17. [Flower species identification and coverage estimation based on hyperspectral remote sensing data in Hulunbeier grassland].

    Science.gov (United States)

    Gai, Ying-Ying; Fan, Wen-Jie; Xu, Xi-Ru; Yan, Bin-Yan; Wang, Huan-Jiong; Liu, Yuan

    2011-10-01

    Monitoring grassland species and area real-timely and accurately is of great significance in species diversity research, as well as in sustainable development of ecosystem. Flowers have their own unique spectral characteristics. Compared with the nutrient stage, species are more easily identified by florescence. So, florescence is a critical period for identification. In the present paper, spectral differences among such flowers as Galium verum Linn., Hemerocallis citrina Baroni, Serratula centauroides Linn., Clematis hexapetala Pall., Lilium concolor var. pulchellum, Lilium pumilum and Artemisia frigida Willd. Sp. Pl. were found, along with identification methods, by analyzing canopies spectra and parametrizing characteristics. Verification results showed that when the coverage of flowers was greater than 10%, the accuracy of identification methods would be higher than 90%. On this basis, linear unmixing model was adopted to calculate the area of flowers in quadrates. Results showed that linear unmixing model was an effective method for estimating the coverage of flowers in grassland because the accuracy was about 4%. PMID:22250555

  18. Aerobic desulfurization of biogas by acidic biotrickling filtration in a randomly packed reactor.

    Science.gov (United States)

    Montebello, Andrea M; Mora, Mabel; López, Luis R; Bezerra, Tercia; Gamisans, Xavier; Lafuente, Javier; Baeza, Mireia; Gabriel, David

    2014-09-15

    Biotrickling filters for biogas desulfurization still must prove their stability and robustness in the long run under extreme conditions. Long-term desulfurization of high loads of H2S under acidic pH was studied in a lab-scale aerobic biotrickling filter packed with metallic Pall rings. Reference operating conditions at steady-state corresponded to an empty bed residence time (EBRT) of 130s, H2S loading rate of 52gS-H2Sm(-3)h(-1) and pH 2.50-2.75. The EBRT reduction showed that the critical EBRT was 75s and the maximum EC 100gS-H2Sm(-3)h(-1). Stepwise increases of the inlet H2S concentration up to 10,000 ppmv lead to a maximum EC of 220gS-H2Sm(-3)h(-1). The H2S removal profile along the filter bed indicated that the first third of the filter bed was responsible for 70-80% of the total H2S removal. The oxidation rate of solid sulfur accumulated inside the bioreactor during periodical H2S starvation episodes was verified under acidic operating conditions. The performance under acidic pH was comparable to that under neutral pH in terms of H2S removal capacity. However, bioleaching of the metallic packing used as support and chemical precipitation of sulfide/sulfur salts occurred. PMID:25151242

  19. Process-Costing, Job-Order-Costing, Operation Costing (også kaldet Batch Costing og Functional Costing - Når Systemtankegangen ligger til grund for økonomistyringen og dens beslutninger)

    DEFF Research Database (Denmark)

    Nielsen, Steen

    2005-01-01

    De tre begreber process-costing, job-order-costing, operation-costing samt functional-based costing er faktisk historiske begreber som stammer langt tilbage i økonomistyringslitteraturen, faktisk tilbage til Scientific Management bevægelsen fra 20'erne og 30'erne. Man kan derfor ikke sige, at disse...... Aktivitets-Baseret Cost Management systemerne. Det er derfor vigtigt dels at kende sin historie på området, dels at gøre sig klart, om de under visse antagelser stadig har deres berettigelse. De samme begreber har også deres pendant til de danske begreber, afdelings- eller funktionsregnskabet samt...... ordreregnskabet, f.eks. som dette er analyseret hos Palle Hansen og Vagn Madsen. Begrebet operational costing anvendes også, men dette dækker i realiteten over, hvordan og hvilke elementer der indgår i hele virksomhedens regnskabs-information-system. Dvs. at dette mere er et spørgsmål om, hvordan systemerne er...

  20. Diversity of arbuscular mycorrhizal fungi associated with desert ephemerals growing under and beyond the canopies of Tamarisk shrubs

    Institute of Scientific and Technical Information of China (English)

    SHI Zhaoyong; ZHANG Liyun; FENG Gu; Christie Peter; TIAN Changyan; LI Xiaolin

    2006-01-01

    The arbuscular mycorrhizal (AM) fungal status of the four most common ephemeral plant species, Chorispora tenella (Pall.) DC., Ceratocephalus testiculatus (Crantz) Bess., Eremopyrum orientale (L.) Jaub et. Spash and Veronica campylopoda Boiss growing in an area dominated by Tamarisk shrubs (Tamarix spp.) was investigated.Samples of the four ephemerals and their rhizosphere soils were collected from underneath and beyond the canopies of the Tamarisk shrubs.Plant mycorrhizal status and soil AM fungal spore densities and community structures were analyzed and compared under and beyond the shrub canopies.The mycorrhizal colonization rates of the ephemerals and spore densities in their corresponding rhizosphere soils were significantly lower under the shrub canopies than beyond. The number of AM fungal species under the shrubs (12) was also lower than beyond the canopies (19). When soil properties in the rhizospheres of the four ephemerals were examined, available N and P and total P, organic matter content, total salt content and electrical conductivity (EC) were all higher under the canopies than beyond. In contrast, soil available K and pH showed no such trend. A total of 21 AM fungal species were isolated from rhizosphere soils of the four ephemerals. Five belonged to Acaulospora, one to Archaeospora, thirteen to Glomus and two to Paraglomus. We conclude that the canopies of Tamarix spp. exerted some influence on the AM status of the ephemerals and on the AM fungal communities and some of the properties of their rhizosphere soils.

  1. Molecular characterization of RsMPK2, a C1 subgroup mitogen-activated protein kinase in the desert plant Reaumuria soongorica.

    Science.gov (United States)

    Liu, Yubing; Li, Xinrong; Tan, Huijuan; Liu, Meiling; Zhao, Xin; Wang, Jin

    2010-01-01

    Reaumuria soongorica (Pall.) Maxim. is a short woody shrub widely found in semi-arid areas of China, and can survive severe environmental stresses. To understand its potential signaling transduction pathway in stress tolerance, we investigated the participation of mitogen-activated protein kinases (MAPKs) as possible mediators of abiotic stresses. A novel MAP kinase cDNA (RsMPK2) that encodes a 374 amino acid protein was isolated from R. soongorica. RsMPK2 belongs to the C1 subgroup, which is still functionally uncharacterized compared to groups A and B; and contains all 11 of the conserved MAPK subdomains and the TEY phosphorylation motif. RsMPK2 is expressed in vegetative (root, stem, leaf and callus) and reproductive (flower) organs. The transcripts of RsMPK2 were rapidly accumulated at high levels when R. soongorica was subjected to dehydration, salinity conditions and treatment with abscisic acid or hydrogen peroxide. Growth analysis of Escherichia coli (srl::Tn10) cells transformed with pPROEXHT-RsMPK2 showed that the expression products of RsMPK2 do not act as an osmoprotectant. But, the inhibition of RsMPK2 expression by the inhibitor U0126 induced a decrease of antioxidant enzyme activity under stresses, indicating that RsMPK2 is involved in the regulation of the antioxidant defense system in the response to stress signaling. PMID:20833058

  2. Integrating sand control, completion decisions pay off

    Energy Technology Data Exchange (ETDEWEB)

    Renfro, K.D.; Procyk, A.

    1998-10-01

    Anadarko recently completed an open-hole, horizontal gas well in the Gulf of Mexico using completion and sand control techniques that have proven extremely successful, judging from the production numbers. The well, in the East Addition, High Island Area, about 120 miles southeast of Galveston in 341-ft waters, was completed with a Pall Stratapac Sand Control Screen without a gravel pack. The flow rate of the well is four to sic times what would have been expected from a conventional, vertical, gravel-packed well with similar conditions. The well`s peak production rate was 22.0 MMcfd, and the well produced a total of more than 2.635 bcf of gas from November 1997 to July 1998. Drawdown was calculated at less than 40 psi, and a skin factor of negative 3.5 indicates that formation damage during the completion was negligible. The full range of completion and sand control decisions came together to make this well a success.

  3. ВИДЫ РОДОВ БОЯРЫШНИК ( CRATAEGUS L., ROSACEAE) И ЯСЕНЬ ( FRAXINUS L., OLEACEAE) В Г. ПЕРМИ

    OpenAIRE

    МОЛГАНОВА НАТАЛЬЯ АЛЕКСАНДРОВНА; ОВЕСНОВ СЕРГЕЙ АЛЕКСАНДРОВИЧ

    2015-01-01

    В литературных источниках приводилось для г. Перми по 4 вида из родов Crataegus L. ( Rosaceae ) и Fraxinus L. ( Oleaceae ). При изучении видового состава этих родов было подтверждено произрастание 2 видов рода Crataegus ( C. sanguinea Pall., C. maximowiczii Schneid.) и 3 видов рода Fraxinus ( F. pennsylvanica Marshall., F. americana L. и F. lanceolata Borkh.). В роде Crataegus обнаружено 5 видов ( C. chrysocarpa Asche, C. сhlorocarpa Lenne et C. Koch, C. chlorosarca Maxim., C. douglasii Lindl...

  4. Determination of antioxidant effects of some plant species wild growing in Turkey.

    Science.gov (United States)

    Serteser, Ahmet; Kargioğlu, Mustafa; Gök, Veli; Bağci, Yavuz; Ozcan, Mehmet Musa; Arslan, Derya

    2008-01-01

    In this study, the antioxidant activity of 50% aqueous methanol extracts of Crataegus tanacetifolia (Lam.) Pers, Crataegus bornmuelleri Zaberi, Crataegus orientalis Pall. ex M.Bieb. var. orientalis, Crataegus szovitsii Pojark, Crataegus curvisepala Lindm., Crataegus monogyna Jacq. subsp. monogyna, Crataegus monogyna Jacq.subsp. azarella (Gris.) Franco, Crataegus micophylla C.Koch, Rosa foetida Herrm., Rosa hemisphaerica J.Herrm., Rosa pulverulenta M.Bieb., Rosa canina L., Rubus discolor Weihe & Nees, Rubus canescens DC. var. canescens, Rubus sanctus Screber, Rubus caesius L., Sorbus umbellata (Desf.) Fritsch var. umbellata, Prunus avium L. (Moench.) and Prunus cerasus L. Mespilus germenica was evaluated by various antioxidant assays, including free radical scavenging, hydrogen peroxide scavenging and metal-chelating activities. The extracts of R. hemisphaerica J.Herrm., P. cerasus L. and R. canina L. showed more stronger free radical scavenging and hydrogen peroxide scavenging activities, and the extracts of R. foetida Herrm. (62.54%) and P. cerasus L. showed stronger metal-chelating activity. The results obtained in the present study indicated that the R. hemisphaerica J.Herrm., P. cerasus L. and R. canina are potential sources of natural antioxidant. These antioxidant properties depend on the concentration of the sample. PMID:19382350

  5. Validation testing of radioactive waste drum filter vents

    International Nuclear Information System (INIS)

    The minimum requirements for Drum Filter Vents (DFVs) can be met by demonstrating conformance with the Waste Isolation Pilot Plant (WIPP) Trupact II Safety Assessment Report (SAR), and conformance with U.S. Federal shipping regulations 49 CFR 178.350, DOT Spec 7A, for Type A packages. These together address a number of safety related performance parameters such as hydrogen diffusivity, flow related pressure drop, filtration efficiency and, separately, mechanical stability and the ability to prevent liquid water in-leakage. In order to make all metal DFV technology (including metallic filter medium) available to DOE sites, Pall launched a product development program to validate an all metal design to meet these requirements. Numerous problems experienced by DOE sites in the past came to light during this development program. They led us to explore enhancements to DFV design and performance testing addressing these difficulties and concerns. The result is a patented all metal DFV certified to all applicable regulatory requirements, which for the first time solves operational and health safety problems reported by DOE site personnel but not addressed by previous DFV's. The new technology facilitates operations (such as manual, automated and semi-automated drum handling/redrumming), sampling, on-site storage, and shipping. At the same time, it upgrades filtration efficiency in configurations documented to maintain filter efficiency following mechanical stress. 2 refs., 2 figs., 10 tabs

  6. Characterization of the Anti-Influenza Activity of the Chinese Herbal Plant Paeonia lactiflora

    Directory of Open Access Journals (Sweden)

    Jin-Yuan Ho

    2014-04-01

    Full Text Available Bai Shao (BS, the root of Paeonia lactiflora Pall., a common Chinese herb in many recipes used to treat viral infection and liver diseases, is recognized for its ability to nourish menstruation, its Yin convergence, and as an antiperspirant. However, the mechanism and components for its antiviral function remain to be elucidated. In this study, an ethanolic extract of BS was further partitioned into aqueous and organic parts (EAex for in vitro functional study and in vivo efficacy testing. EAex exhibited an IC50 of 0.016 ± 0.005 mg/mL against influenza virus A/WSN/33 (H1N1, with broad-spectrum inhibitory activity against different strains of human influenza A viruses, including clinical oseltamivir-resistant isolates and an H1N1pdm strain. The synthesis of both viral RNA and protein was profoundly inhibited when the cells were treated with EAex. A time-of-addition assay demonstrated that EAex exerted its antiviral activity at various stages of the virus replication cycle. We addressed its antiviral activity at virus entry and demonstrated that EAex inhibits viral hemagglutination and viral binding to and penetration into host cells. In vivo animal testing showed that 200 mg/kg/d of EAex offered significant protection against viral infection. We conclude that BS possesses antiviral activity and has the potential for development as an anti-influenza agent.

  7. Differential Responses to Simulated Precipitation Exhibited by a Typical Shrub and a Herb Coexisted in Hunshandak Sandy Land

    Institute of Scientific and Technical Information of China (English)

    NIUShu-Li; PENGYu; JIANGGao-Ming; LIYong-Geng; GAOLei-Ming; LIUMei-Zhen; CUIHong-Xia; DINGLi

    2004-01-01

    To assess the ecophysiological responses and adaptive strategies to rainfall exhibited by different plant functional types, we compared gas exchange, leaf water potential (ψleaf) and PS photochemical efficiency (Fv/Fm) between Hedysarum fruticosum Pall. (shrub) and Salsola collina Y. L. Chang(herb) under a series of simulated rainfalls. The experiment was conducted in Hunshandak Sandy Land, North China. The values of net photosynthetic rate (Pn), transpiration rate (E), stomatal conductance (gs), Fv/Fm and ψleaf always elevated with the increasing amount of simulated rainfall. Whereas water useefficiency (WUE) maintained constant in H. fruticosum while always decreased in S.collina. Both speciesfully recovered their Pn and Fv/Fm 3d after rainfall, while gs and ψleaf recovered only within 2 d. However, the response patterns were obviously different. H.fruticosu promote its physiological traits within 5-15 mm rainfall but no further positive enhancement was noted when rainfall was larger than 15 mm. In S.collina, however, the enhancement continued with more water applied. We inferred that H.fruticosum and S.collina responded similarly to rainfall in time courses but differential to simulated precipitation change. S.collina was likely to be physiologically sensitive to instant increasing soil water, that can be regarded as a prodigal water use type; whilst H.fruticosum was a conservative water user.

  8. Structural characterisation of the polysaccharides from endemic Mongolian desert plants and their effect on the intestinal absorption of ovalbumin.

    Science.gov (United States)

    Golovchenko, Victoria V; Khramova, Daria S; Shashkov, Alexandre S; Otgonbayar, Dorjgoo; Chimidsogzol, Aria; Ovodov, Yury S

    2012-07-15

    Using successive extractions with water and 0.7% aqueous ammonium oxalate, pectic polysaccharides were isolated from the following plants growing in the arid climate of Mongolia (Gobi): saxaul Haloxylon ammodendron Maxim., rhubarb Rheum nanum Sievers, Nitraria sibirica Pall., Peganum harmala L. and almond Amygdalus mongolica Maxim. The data obtained exhibited the primary synthesis of the cell wall pectic polysaccharides but not the middle lamellae water-soluble pectins in plants growing in the dry climatic zone. Both α-(1→4)-D-galacturonan and α-(1→4)-D-galacturonan, which was substituted with methyl groups, were found to be backbone of pectins. The L-arabinofuranose residues were identified as the main components of ramified regions. The pectins from almond differed from other pectins due to a high arabinose content. The data from NMR spectroscopy and methylation analyses demonstrated that pectic polysaccharides from almond included terminal, (1→5)-, (1→3)-linked and 3,5-substituted L-arabinofuranose residues and a small terminal D-galactopyranose and 2,5- and 2,3,5-substituted L-arabinofuranose residue content. The pectic polysaccharides were found to decrease the absorption of ovalbumin (OVA) in the blood from the gut lumen. The serum OVA level was lower in mice fed with OVA mixed with the pectins compared with the control group, which was administered OVA alone. PMID:22549013

  9. Stabilization of Fast Pyrolysis Oil: Post Processing Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Elliott, Douglas C.; Lee, Suh-Jane; Hart, Todd R.

    2012-03-01

    UOP LLC, a Honeywell Company, assembled a comprehensive team for a two-year project to demonstrate innovative methods for the stabilization of pyrolysis oil in accordance with DOE Funding Opportunity Announcement (FOA) DE-PS36-08GO98018, Biomass Fast Pyrolysis Oil (Bio-oil) Stabilization. In collaboration with NREL, PNNL, the USDA Agricultural Research Service (ARS), Pall Fuels and Chemicals, and Ensyn Corporation, UOP developed solutions to the key technical challenges outlined in the FOA. The UOP team proposed a multi-track technical approach for pyrolysis oil stabilization. Conceptually, methods for pyrolysis oil stabilization can be employed during one or both of two stages: (1) during the pyrolysis process (In Process); or (2) after condensation of the resulting vapor (Post-Process). Stabilization methods fall into two distinct classes: those that modify the chemical composition of the pyrolysis oil, making it less reactive; and those that remove destabilizing components from the pyrolysis oil. During the project, the team investigated methods from both classes that were suitable for application in each stage of the pyrolysis process. The post processing stabilization effort performed at PNNL is described in this report. The effort reported here was performed under a CRADA between PNNL and UOP, which was effective on March 13, 2009, for 2 years and was subsequently modified March 8, 2011, to extend the term to December 31, 2011.

  10. Styrene biofiltration in a trickle-bed reactor

    Directory of Open Access Journals (Sweden)

    V. Novak

    2008-04-01

    Full Text Available The biological treatment of styrene waste gas in a trickle-bed filter (TBF was investigated. The bioreactor consisted of a two-part glass cylinder (ID 150 mm filled with 25 mm polypropylene Pall rings serving as packing material. The bed height was 1m. Although the laboratory temperature was maintained at 22 ºC, the water temperature in the trickle-bed filter was slightly lower (about 18 ºC.The main aim of our study was to observe the effect of empty-bed residence time (EBRT on bioreactor performance at a constant pollutant concentration over an extended time period. The bioreactor was inoculated with a mixed microbial consortium isolated from a styrene-degrading biofilter that had been running for the previous two years. After three weeks of acclimation period, the bioreactor was loaded with styrene (100 mg.m-3. EBRT was in the range of 53 s to 13 s. A maximum elimination capacity (EC of 11.3 gC.m-3.h-1 was reached at an organic loading (OL rate of 18.6 gC.m-3.h-1.

  11. HPP Boshkov Most - upgrading of the design installed capacity from 45 MW to 70 MW

    International Nuclear Information System (INIS)

    HPP Boshkov Most location will be near the town of Debar, accessible from Mavrovo-Debar road. This procject involves the tributaries that combine to make up the Mala Reka, the biggest tributary to Radika river. The watershed area is characterized as having high mountains and rich watercourses, without major settlements. The hydro system consists of: The Tresonche reservoir with 44 m high dam, with an intake to head race tunnel, also additional intakes linked by a system siphons, covered channels collect the waters from high mountains and deliver their flow to the head race tunnel. The head race tunnel ends with surge shaft and penstocks to the powerhouse. In this paper will be given differences between the Main Design prepared by HEP - Skopje in 1983, where the installed capacity is 45 MW and feasibility Study prepared by Pall C. Rizzo Ass., where installed capacity is suggested to be 70 MW, thru enlarged nominal discharge - from 14 m3/s to 22 m3/s. (Author)

  12. Harvest season, high polluted season in East China

    International Nuclear Information System (INIS)

    East China, a major agricultural zone with a dense population, suffers from severe air pollution during June, the agricultural harvest season, every year. Crop burning emits tremendous amounts of combustion products into the atmosphere, not only rapidly degrading the local air quality but also affecting the tropospheric chemistry, threatening public health and affecting climate change. Recently, in mid-June 2012, crop fires left a thick pall of haze over East China. We evaluated the PM10, PM2.5 (particulates less than 10 and 2.5 μm in aerodynamic diameter) and BC (black carbon) emissions by analyzing detailed census data and moderate resolution imaging spectroradiometer (MODIS) remote sensing images and then simulated the consequent pollution using meteorological and dispersion models. The results show that the crop fires sweeping from the south to the north are responsible for the intensive air pollution during harvest season. It is necessary for scientists and governments to pay more attention to this issue. (letter)

  13. Are oxygen isotopes of sulfate a useful tool for the quantification of sulfate reduction in a BTEX contaminated aquifer?

    International Nuclear Information System (INIS)

    were analyzed for the content of dissolved sulfate and sulfide as well as for the isotopic composition of sulfate (δ34S, δ18O) and sulfide (δ34S). The isotopic composition of sulfur in sulfate and sulfide from laboratory and groundwater samples are shown. In both cases, the typical correlation between the fraction of the residual sulfate and the δ34S-SO4 proves the occurrence of BSR. The average enrichment factors for 34S were calculated from logarithmic fits of the respective data sets using a Rayleigh equation. While the experimental enrichment factor between SO4 and S2- was -23.4 per mille, a slightly smaller value of -17.5 per mille was observed for field samples. Both values are consistent with previously reported data. δ34S-S2- values obtained during the laboratory experiments are in accordance with the expected values for the given enrichment factor in a system that is characterized by the accumulation of a product reservoir. For groundwater samples the measured δ34S-S2- values do neither match the expected values for an accumulating product reservoir nor the values expected for an open system with H2S-loss. As shown, no correlation exists between the fraction of the residual sulfate and the δ18O-SO4. The absence of the typical 18O-enrichment can be caused either by the interference of the kinetic isotope effect with an approaching isotopic equilibrium between oxygen in sulfate and water or by the superimposition of BSR by the bacterial disproportionation of S0 to SO4 and H2S (BDS). A general lack of an oxygen isotope effect, e.g. due to the high load of organic contaminants, can be ruled out, since a significant oxygen isotope shift of more than 5 per mille between the initial sulfate and the sulfate in the microcosm experiments was observed. The oxygen isotopes of sulfate in groundwater samples show a much different behavior. A strong correlation exists between the fraction of the residual sulfate and the measured δ18O-SO4. However, this correlation is

  14. Are oxygen isotopes of sulfate a useful tool for the quantification of sulfate reduction in a BTEX contaminated aquifer?

    International Nuclear Information System (INIS)

    samples were analyzed for the content of dissolved sulfate and sulfide as well as for the isotopic composition of sulfate (δ34S, δ18O) and sulfide (δ34S). The isotopic composition of sulfur in sulfate and sulfide from laboratory and groundwater samples are shown, respectively. In both cases, the typical correlation between the fraction of the residual sulfate and the (δ34S-SO4 proves the occurrence of BSR. The average enrichment factors for 34S were calculated from logarithmic fits of the respective data sets using a Rayleigh equation. While the experimental enrichment factor between SO4 and S2- was -23.4 per mille, a slightly smaller value of -17.5 per mille was observed for field samples. Both values are consistent with previously reported data. δ34S-S2- values obtained during the laboratory experiments are in accordance with the expected values for the given enrichment factor in a system that is characterized by the accumulation of a product reservoir. For groundwater samples the measured δ34S-S2- values do neither match the expected values for an accumulating product reservoir nor the values expected for an open system with H2S-loss. As shown, no correlation exists between the fraction of the residual sulfate and the δ18O-SO4. The absence of the typical 18O-enrichment can be caused either by the interference of the kinetic isotope effect with an approaching isotopic equilibrium between oxygen in sulfate and water or by the superimposition of BSR by the bacterial disproportionation of S0 to SO4 and H2S (BDS). A general lack of an oxygen isotope effect, e.g. due to the high load of organic contaminants, can be ruled out, since a significant oxygen isotope shift of more than 5 per mille between the initial sulfate and the sulfate in the microcosm experiments was observed. The oxygen isotopes of sulfate in groundwater samples show a much different behaviour. A strong correlation exists between the fraction of the residual sulfate and the measured δ18O-SO4. However

  15. Depressão e qualidade de vida em pacientes com fibromialgia Depression and quality of life among patients with fibromyalgia

    Directory of Open Access Journals (Sweden)

    AMB Santos

    2006-09-01

    Full Text Available CONTEXTO: Fibromialgia é uma síndrome reumática caracterizada por dor musculoesquelética difusa e crônica, e sítios dolorosos específicos à palpação (tender points. Freqüentemente é associada à fadiga generalizada, distúrbios do sono, rigidez matinal, dispnéia, ansiedade, alterações no humor que podem evoluir para um quadro de depressão. Sendo assim, afeta negativamente a qualidade de vida das pessoas. No entanto, ainda não se sabe o poder de discriminação dos instrumentos de avaliação da depressão e qualidade de vida. O objetivo desse estudo foi avaliar a depressão e a qualidade de vida de pacientes com fibromialgia e avaliar o poder de discriminação de instrumentos relacionados a esses aspectos. MÉTODO: Para avaliar a qualidade de vida foram utilizados dois instrumentos: um específico, o Fibromyalgia Impact Questionnaire (FIQ e outro genérico, o Medical Outcomes Study 36-item Short-Form Healthy Survey (SF-36; para avaliar a depressão, a Escala de Depressão de Beck (BDS. Participaram do estudo 40 mulheres sendo 20 com fibromialgia - Grupo teste e 20 saudáveis - Grupo controle. Os três protocolos foram aplicados aos indivíduos dos dois grupos em uma única sessão de avaliação. Toda a análise estatística foi realizada utilizando-se o teste "t" Student, com significância alfa = 0,05. RESULTADOS: Houve diferença estatisticamente significante entre os grupos controle e teste em todos os questionários (pBACKGROUND: Fibromyalgia is a rheumatic syndrome characterized by widespread chronic musculoskeletal pain and specific palpable tender points. It is often associated with generalized fatigue, sleep disturbances, morning stiffness, dyspnea, anxiety and mood disturbances that may evolve into depression. Thus, such individuals' quality of life is negatively affected. However, the discriminating power of quality-of-life and depression assessment instruments is still unknown. OBJECTIVE: To assess depression and

  16. Identification of a cell-penetrating peptide domain from human beta-defensin 3 and characterization of its anti-inflammatory activity

    Directory of Open Access Journals (Sweden)

    Lee JY

    2015-08-01

    Full Text Available Jue Yeon Lee,1,* Jin Sook Suh,2,* Jung Min Kim,1 Jeong Hwa Kim,1 Hyun Jung Park,1 Yoon Jeong Park,1,2 Chong Pyoung Chung1 1Central Research Institute, Nano Intelligent Biomedical Engineering Corporation (NIBEC, Chungcheongbuk-do, Republic of Korea; 2Dental Regenerative Biotechnology, Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea *These authors contributed equally to this work Abstract: Human beta-defensins (hBDs are crucial factors of intrinsic immunity that function in the immunologic response to a variety of invading enveloped viruses, bacteria, and fungi. hBDs can cause membrane depolarization and cell lysis due to their highly cationic nature. These molecules participate in antimicrobial defenses and the control of adaptive and innate immunity in every mammalian species and are produced by various cell types. The C-terminal 15-mer peptide within hBD3, designated as hBD3-3, was selected for study due to its cell- and skin-penetrating activity, which can induce anti-inflammatory activity in lipopolysaccharide-treated RAW 264.7 macrophages. hBD3-3 penetrated both the outer membrane of the cells and mouse skin within a short treatment period. Two other peptide fragments showed poorer penetration activity compared to hBD3-3. hBD3-3 inhibited the lipopolysaccharide-induced production of inducible nitric oxide synthase, nitric oxide, and secretory cytokines, such as interleukin-6 and tumor necrosis factor in a concentration-dependent manner. Moreover, hBD3-3 reduced the interstitial infiltration of polymorphonuclear leukocytes in a lung inflammation model. Further investigation also revealed that hBD3-3 downregulated nuclear factor kappa B-dependent inflammation by directly suppressing the degradation of phosphorylated-IκBα and by downregulating active nuclear factor kappa B p65. Our findings indicate that hBD3-3 may be conjugated with drugs of interest to ensure their proper translocation to

  17. Phenology of forest-grassland transition zones in the Community Land Model

    Science.gov (United States)

    Dahlin, K.; Fisher, R. A.

    2013-12-01

    Forest-grassland transition zones (savannas, woodlands, wooded grasslands, and shrublands) are highly sensitive to climate and may already be changing due to warming, changes in precipitation patterns, and/or CO2 fertilization. Shifts between closed canopy forest and open grassland, as well as shifts in phenology, could have large impacts on the global carbon cycle, water balance, albedo, and on the humans and other animals that depend on these regions. From an earth system perspective these impacts may then feed back into the climate system and impact how, when, and where climate change occurs. Here we compare 29 years of monthly leaf area index (LAI) outputs from several offline versions of the Community Land Model (CLM), the land component of the Community Earth System Model, to LAI derived from the AVHRR NDVI3g product (LAI3g). Specifically, we focus on seasonal patterns in regions dominated by tropical broadleaved deciduous trees (T-BDT), broadleaved deciduous shrubs (BDS) and grasslands (C3 and C4) in CLM, all of which follow a 'stress deciduous' phenological algorithm. We consider and compare two versions of CLM (v. 4CN and v. 4.5BGC) to the satellite derived product. We found that both versions of CLM were able to capture seasonal variations in grasslands relatively well at the regional scale, but that the 'stress deciduous' phenology algorithm did not perform well in areas dominated by T-BDT or BDS. When we compared the performance of the models at single points we found slight improvements in CLM4.5BGC over CLM4CN, but generally that the magnitude of seasonality was too low in CLM as compared to the LAI3g satellite product. To explore the parameters within CLM that had the most leverage on seasonality of LAI, we used a Latin hypercube approach to vary values for critical soil water potential (threshold at which plants drop leaves), the critical number of days that soil water potential must be too low for leaves to drop, and the carbon allocation scheme

  18. 分子印迹固相萃取-液相色谱法测定喘息灵胶囊中盐酸克仑特罗的含量%Determination of clenbuterol hydrochloride with molecularly imprinted solid phase extraction- high performance liquid chromatography in Chuangxiling capsules

    Institute of Scientific and Technical Information of China (English)

    黄红萍; 游勇基

    2012-01-01

    目的:建立分子印迹固相萃取-高效液相色谱法测定喘息灵中盐酸克仑特罗含量.方法:采用Hypersil BDS C18 (250mm×4.6 mm,5μm)色谱柱,以0.05 moL·L-1NaH2P04(含0.005 moL·L-1PIC - B6,用磷酸调pH至4.0左右)和甲醇(60∶40)为流动相,检测波长为245 nm,流速为1.0 mL·min-1;柱温为室温.结果:盐酸克仑特罗浓度在0.4~40.0 μg·mL-1范围内呈良好线性关系(r =0.9998),盐酸克仑特罗的平均回收率为97.8%,(RSD为0.9%,n=9).结论:方法简便,分离效果好,结果准确可靠.%Objective: To establish a method for determination of clenbuterol hydrochloride in Chuanxiling with mo-lecularly imprinted solid phase extraction -high performance liquid chromatography. Methods: The analysis was carried on a Hypersil BDS C18(250 mm ×4. 6 mm,5 μm) column;The mobile phase was composed of 0. 05 moL·L-1 NaH2PO4(containing 0. 005 moL·L-1 PIC - B6,adjust the pH to 4. 0 with phosphoric acid) and methanol (60:40) ;the detection wavelength was 245 nm and the flow rate was 1. 0 mL·min-1; column temperature was at room temperature. Results: The linear range was 0. 4 - 40. 0μg·mL-1' (r = 0. 9998 ) for clenbuterol hydrochloride, the average recovery of clenbuterol hydrochloride was 97. 8% (RSD = 0. 9% , n - 9). Conclusion: This method is simple,rapid and accurate.

  19. Assessment of anxiety and depression in adolescents with acne vulgaris related to the severity of clinical features and gender

    Directory of Open Access Journals (Sweden)

    Nermina Kurtalić

    2010-11-01

    Full Text Available Objective. To determine anxiety and depression levels in adolescents with acne vulgaris in relation to clinical severity and gender. Patients and methods. Using a sectional study, the anxiety and depression level was analyzed of 90 adolescents of both sexes, aged 16 to 21 years, who were suffering from acne vulgaris. The study was conducted between February 1st 2008 and January 31st 2009 at the Dermatovenerology department of the Cantonal Hospital “Dr. Irfan Ljubijankić”, Bihac. According to the type of efflorescence, its localization and severity of clinical features, respondents were classified in three groups: the first group consisted of adolescents with mild forms of acne, the second group had moderate forms of acne and the third had severe forms of acne. Evaluation of anxiety levels in patients with acne vulgaris was made using STAI questionnaire (Spielberger’s state and trait Anxiety Inventory that consists of 20 questions about the essential characteristics of anxiety as the condition, and the level of depression was determined using the BDS-scale (Back Depression Inventory which consists of 18 items that were used by the respondents to perform self-evaluation of depression level. Results. In the study group there were 54 (60% female respondents and 36 (40% male, mean age 17.5 years (range 15.6-20.6. Of the total number of patients with acne vulgaris, nine of them or 10% (4 female and 5 male had a mild form of acne (first group, 72 of them or 80% (46 female and 26 male a moderate form of acne (second group and 9 of them or 10 % (4 female and 5 male a severe form of acne (third group (p > 0.95. 1.1% of the respondents had an exceptionally low anxiety level, 13.3% had low level, moderate 76.8% and 8.8% had a high level. 37.8% had distinct signs of depression, the risk group consisted of 44.4%, and a normal value was found in 17.7%. The values of the STAI questionnaire expressed as median (range in the first, second and third groups

  20. Magellan adaptive optics first-light observations of the exoplanet β PIC b. I. Direct imaging in the far-red optical with MagAO+VisAO and in the near-IR with NICI ,

    International Nuclear Information System (INIS)

    We present the first ground-based CCD (λ < 1 μm) image of an extrasolar planet. Using the Magellan Adaptive Optics system's VisAO camera, we detected the extrasolar giant planet β Pictoris b in Y-short (YS , 0.985 μm), at a separation of 0.470 ± 0.''010 and a contrast of (1.63 ± 0.49) × 10–5. This detection has a signal-to-noise ratio of 4.1 with an empirically estimated upper limit on false alarm probability of 1.0%. We also present new photometry from the Gemini Near-Infrared Coronagraphic Imager instrument on the Gemini South telescope, in CH 4S,1% (1.58 μm), KS (2.18 μm), and K cont (2.27 μm). A thorough analysis of our photometry combined with previous measurements yields an estimated near-IR spectral type of L2.5 ± 1.5, consistent with previous estimates. We estimate log (L bol/L ☉) = –3.86 ± 0.04, which is consistent with prior estimates for β Pic b and with field early-L brown dwarfs (BDs). This yields a hot-start mass estimate of 11.9 ± 0.7 M Jup for an age of 21 ± 4 Myr, with an upper limit below the deuterium burning mass. Our L bol-based hot-start estimate for temperature is T eff = 1643 ± 32 K (not including model-dependent uncertainty). Due to the large corresponding model-derived radius of R = 1.43 ± 0.02 R Jup, this T eff is ∼250 K cooler than would be expected for a field L2.5 BD. Other young, low-gravity (large-radius), ultracool dwarfs and directly imaged EGPs also have lower effective temperatures than are implied by their spectral types. However, such objects tend to be anomalously red in the near-IR compared to field BDs. In contrast, β Pic b has near-IR colors more typical of an early-L dwarf despite its lower inferred temperature.

  1. Quantification of Arbutin from Pear Blossoms by HPLC%梨花中熊果苷的高效液相色谱分析

    Institute of Scientific and Technical Information of China (English)

    李媛; 乔进春; 张玉星; 何童森; 吕明霞; 张飞; 崔同

    2012-01-01

    采用高效液相色谱法对不同时期、不同品种的梨花中熊果苷的含量进行了分析,色谱柱为Hypersil BDS C18 (4.6 mm×250 mm,5μm),流动相为甲醇:水(6:94),加入甲酸0.05%,检测波长280 nm.结果表明:熊果苷在0.01 ~5.00 μg范围内线性关系良好(r=0.9999),平均加标回收率为97.7%.不同生长期的鸭梨梨花中熊果苷的含量一般在10 mg/g以上,尤以花芽萌动期时含量最高,达到35.7 mg/g(鲜重计).不同品种的9份梨花样品中,熊果苷含量在3.5 -10.5 mg/g之间.%The contents of arbutin in pear blossoms of different periods and different varieties were detected using the HPLC method with Hypersil BDS C18 column (4.6 mm × 250 mm,5 μm), the mobile phase methanol: water (6:94, with 0.05% formic acid), and the detection wavelength 280 nm. The results showed that the calibration curve was linear in the range of 0.01 ~5.00μg (r = 0.9999) and the average recovery was 97.7%. The content of arbutin in Yali pear blossom during the florescence was above 10 mg/g (fresh weight) in most cases,especially in blossom bud germination period,reaching a maximum of 35.7 mg/g. In the nine pear blossom samples from different varieties,the contents of arbutin were range between 3.5 mg/g to 10.5 mg/g.

  2. Establishment of HPLC Fingerprint of Ramulus Uncariae Cum Uncis%钩藤HPLC指纹图谱的构建

    Institute of Scientific and Technical Information of China (English)

    何昱; 黄家卫; 杨维

    2011-01-01

    OBJECTIVE: To establish the HPLC fingerprint of Ramulus Uncariae Cum Uncis, and to provide objective basis for the quality control of Ramulus Uncariae Cum Uncis based on the results of the content determination of rhynchophylline and isorhynchophylline. METHODS: The determination was performed on Hypersil BDS C18(250 mm×4.6 mm, 5 μm) column with the mobile phase consisted of methanol-0.02% triethylamine-water (gradient elution). The flow rate was 1.0 mL· min-1 and UV detection wavelength was 254 nm. RESULTS: The HPLC fingerprints of Ramulus Uncariae Cum Uncis were established according to the chromatographic data of 10 batches of samples. The results of similarity evaluation and principle component analysis (PCA)were favorable. CONCLUSION: Established fingerprint reflects the inherent character of Ramulus Uncariae Cum Uncis and can be used for the quality evaluation of it.%目的:建立钩藤药材的高效液相色谱(HPLC)指纹图谱,并结合钩藤碱和异钩藤碱的含量测定结果,为钩藤药材的质量控制提供客观依据.方法:色谱柱为依利特 Hypersil BDS C18(250 mm×4.6 mm,5μm),流动相为甲醇-含0.02%三乙胺的水(梯度洗脱),流速为1.0mL·min-1,紫外检测波长为254nm.结果:依照10个批次样品的色谱数据构建起钩藤药材的HPLC指纹图谱,相似度评价和主成分分析的结果良好.结论:所构建的指纹图谱可以反映钩藤药材的内在组成,作为其质量评价的标准.

  3. The Effects of a Brief Acceptance-based Behavior Therapy vs. Traditional Cognitive Behavior Therapy for Public Speaking Anxiety: Differential Effects on Performance and Verbal Working Memory

    Science.gov (United States)

    Glassman, Lisa Hayley

    Individuals with public speaking phobia experience fear and avoidance that can cause extreme distress, impaired speaking performance, and associated problems in psychosocial functioning. Most extant interventions for public speaking phobia focus on the reduction of anxiety and avoidance, but neglect performance. Additionally, very little is known about the relationship between verbal working memory and social performance under conditions of high anxiety. The current study compared the efficacy of two cognitive behavioral treatments, traditional Cognitive Behavioral Therapy (tCBT) and acceptance-based behavior therapy (ABBT), in enhancing public speaking performance via coping with anxiety. Verbal working memory performance, as measured by the backwards digit span (BDS), was measured to explore the relationships between treatment type, anxiety, performance, and verbal working memory. We randomized 30 individuals with high public speaking anxiety to a 90-minute ABBT or tCBT intervention. As this pilot study was underpowered, results are examined in terms of effect sizes as well as statistical significance. Assessments took place at pre and post-intervention and included self-rated and objective anxiety measurements, a behavioral assessment, ABBT and tCBT process measures, and backwards digit span verbal working memory tests. In order to examine verbal working memory during different levels of anxiety and performance pressure, we gave each participant a backwards digit span task three times during each assessment: once under calm conditions, then again while experiencing anticipatory anxiety, and finally under conditions of acute social performance anxiety in front of an audience. Participants were asked to give a video-recorded speech in front of the audience at pre- and post-intervention to examine speech performance. Results indicated that all participants experienced a very large and statistically significant decrease in anxiety (both during the speech and BDS

  4. Calorimetric and relaxation properties of xylitol-water mixtures

    Science.gov (United States)

    Elamin, Khalid; Sjöström, Johan; Jansson, Helén; Swenson, Jan

    2012-03-01

    We present the first broadband dielectric spectroscopy (BDS) and differential scanning calorimetry study of supercooled xylitol-water mixtures in the whole concentration range and in wide frequency (10-2-106 Hz) and temperature (120-365 K) ranges. The calorimetric glass transition, Tg, decreases from 247 K for pure xylitol to about 181 K at a water concentration of approximately 37 wt. %. At water concentrations in the range 29-35 wt. % a plentiful calorimetric behaviour is observed. In addition to the glass transition, almost simultaneous crystallization and melting events occurring around 230-240 K. At higher water concentrations ice is formed during cooling and the glass transition temperature increases to a steady value of about 200 K for all higher water concentrations. This Tg corresponds to an unfrozen xylitol-water solution containing 20 wt. % water. In addition to the true glass transition we also observed a glass transition-like feature at 220 K for all the ice containing samples. However, this feature is more likely due to ice dissolution [A. Inaba and O. Andersson, Thermochim. Acta, 461, 44 (2007)]. In the case of the BDS measurements the presence of water clearly has an effect on both the cooperative α-relaxation and the secondary β-relaxation. The α-relaxation shows a non-Arrhenius temperature dependence and becomes faster with increasing concentration of water. The fragility of the solutions, determined by the temperature dependence of the α-relaxation close to the dynamic glass transition, decreases with increasing water content up to about 26 wt. % water, where ice starts to form. This decrease in fragility with increasing water content is most likely caused by the increasing density of hydrogen bonds, forming a network-like structure in the deeply supercooled regime. The intensity of the secondary β-relaxation of xylitol decreases noticeably already at a water content of 2 wt. %, and at a water content above 5 wt. % it has been replaced by a

  5. Physical Activity Level of Post-menopausal Women with Low Bone Mineral Density.

    Science.gov (United States)

    Dallanezi, Glauber; Freire, Beatriz Funayama Alvarenga; Nahás, Eliana Aguiar Petri; Nahás-Neto, Jorge; Corrente, José Eduardo; Mazeto, Gláucia Maria Ferreira da Silva

    2016-05-01

    Introduction Proper physical activity is related to the prevention and the treatment of osteoporosis. Purpose To assess the level of physical activity (PA) in post-menopausal women with low bone mineral density (BMD). Methods This cross-sectional clinical study included 123 post-menopausal women. The inclusion criteria were: age of ≥ 45 years with last menses at least 12 months prior to the initiation of the study, and bone density scan (BDS) values measured over the preceding 12 months. Women with severe osteoarthritis were excluded. Women were allocated into three groups, according to BMD measured by BDS [osteoporosis (OP; 54 women), osteopenia (35 women), and normal bone density (NBD; 35 women)], and compared for general, clinical, and anthropometric data, and for PA level. The latter was assessed using the International Physical Activity Questionnaire (IPAQ), in metabolic equivalent of task (MET) units. Participants were classified as sedentary, active or very active. Quantitative variables were compared using ANOVA followed by Tukey's test. Associations between qualitative variables were tested by Chi-square (χ2) or Fisher's exact test. In order to check for differences among groups and IPAQ domains, a generalized linear model with Gamma distribution was adjusted for values in METs. Results The OP group differed from the NBD group regarding age (61.8 ± 10.1 and 52.9 ± 5.4 years), percentage of participants with self-declared white ethnicity (43.9 and 28.0%), body mass index (BMI - 25.7 ± 5.4 and 30.9 ± 5.1 kg/m(2)), and time since menopause (15.5 ± 7.5 and 5.8 ± 4.5 years). Smoking rates were higher in the OP (55.6%) and NBD groups (33.3%) than in the osteopenia group (11.1%). Within the OP group, the rate of subjects with sedentary lifestyles was higher (42.6%), and time spent sitting was greater (344.3 ± 204.8 METs) than in the groups with osteopenia (20.0% and 300.9 ± 230.6 METs) and NBD (17.7% and 303

  6. Measurements of fast neutrons by bubble detectors

    International Nuclear Information System (INIS)

    Neutron bubble detectors have been studied using Am-Be and D-D neuron sources, which give limited energy information. The Bubble Detector Spectrometer (BDS) have six different energy thresholds ranging from 10 KeV to 10 Mev. The number of bubbles obtained in each measurement is related to the dose (standardized response R) equivalent neutrons through sensitivity (b / μSv) and also with the neutron flux (neutrons per unit area) through a relationship that provided by the manufacturer. Bubble detectors were used with six different answers (0.11 b/ μSv, 0093 b/μSv, 0.14 b/μSv, 0.17 b/μSv, 0051 b/μSv). To test the response of the detectors (BDS) radiate a set of six of them with different energy threshold, with a source of Am-Be, placing them at a distance of one meter from it for a few minutes. Also, exposed to dense plasma focus Fuego Nuevo II (FN-II FPD) of ICN-UNAM, apparatus which produces fusion plasma, generating neutrons by nuclear reactions of neutrons whose energy emitting is 2.45 MeV. In this case the detectors were placed at a distance of 50 cm from the pinch at 90° this was done for a certain number of shots. In both cases, the standard response is reported (Dose in μSv) for each of the six detectors representing an energy range, this response is given by the expression Ri= Bi / Si where Bi is the number of bubbles formed in each and the detector sensitivity (Si) is given for each detector in (b / μSv). Also, reported for both cases, the detected neutron flux (n cm−2), by a given ratio and the response involves both standardized R, as the average cross section sigma. The results obtained have been compared with the spectrum of Am-Be source. From these measurements it can be concluded that with a combination of bubble detectors, with different responses is possible to measure the equivalent dose in a range of 10 to 100 μSv fields mixed neutron and gamma, and pulsed generated fusion devices

  7. SPE- HPLC determination of pyrethroid pesticide residues in Platycodon grandiflorum%固相萃取-高效液相色谱法测定桔梗中拟除虫菊酯的农药残留

    Institute of Scientific and Technical Information of China (English)

    翁淑琴; 游勇基

    2011-01-01

    目的:建立桔梗中甲氰菊酯、高效氯氟氰菊酯、溴氰菊酯、氰戊菊酯、氯菊酯、联苯菊酯共6个拟除虫菊酯类农药残留的提取、净化及其残留量测定的方法.方法:样品运用石油醚提取,商品CARB/NH2小柱净化,乙腈-二氯甲烷(5:95)洗脱,HPLC - DAD检测.色谱条件:采用Hypersil BDS C18(250 mm ×4.6 mm,5μm)色谱柱,流动相为乙腈-水(70:30),流速1mL·min-1,检测波长230nm.结果:样品4水平添加时的6个拟除虫菊酯类化合物回收率在75.63%~107.5%范围内,RSD在2.3% ~9.9%范围内,可以满足农药残留分析的要求.结论:该方法灵敏度高,选择性强,操作简单、快速,净化效果好.可应用于桔梗药材中痕量农药残留的检测.%Objective: To develop a method for the extraction, clean - up and determination of fenpropathrin, lambda - cyhalothrin, deltamethrin, fenvalerate, permethrin and bifenthrin in Platycodon grandiflorum. Methods: Pesticide residues were extracted from samples with ligarine; Extracts were cleaned - up by CARB/NH2 column, eluted with acetonitrile -chloromethane(5: 95). Analytical screening was determined by HPLC with a diode array detector. HPLC condition:Hypersil BDS C18(250mm ×4. 6 mm,5 μm)column was adopted,the mobile phase consisted of acetonitrile - water(70: 30) at a flow rate of 1 mL · min-1 ,and the detection wavelength was 230 ran. Results; The average recoveries were in the range of 75. 63% - 107. 6% with RSD of 2. 3% - 9. 9%. The method met the requirement of pesticide residue analysis. Conclusion: The proposed method has high sensitivity, repeatability and selectivity, it is simple and fast, which can be used for the analysis of 6 pyrethroid pesticides.

  8. Magellan adaptive optics first-light observations of the exoplanet β PIC b. I. Direct imaging in the far-red optical with MagAO+VisAO and in the near-IR with NICI {sup ,}

    Energy Technology Data Exchange (ETDEWEB)

    Males, Jared R.; Close, Laird M.; Morzinski, Katie M.; Skemer, Andrew J.; Kopon, Derek; Follette, Katherine B.; Hinz, Philip M.; Rodigas, Timothy J. [Steward Observatory, University of Arizona, Tucson, AZ 85721 (United States); Wahhaj, Zahed [European Southern Observatory, Alonso de Cordova 3107, Vitacura, Casilla 19001 Santiago (Chile); Liu, Michael C.; Nielsen, Eric L.; Chun, Mark [Institute for Astronomy, University of Hawaii, 2680 Woodlawn Drive, Honolulu, HI 96822 (United States); Puglisi, Alfio; Esposito, Simone; Riccardi, Armando; Pinna, Enrico; Xompero, Marco; Briguglio, Runa [Arcetri Observatory/INAF, Largo E. Fermi 5, I-50125-Firenze (Italy); Biller, Beth A. [Institute for Astronomy, The University of Edinburgh, Royal Observatory, Blackford Hill, Edinburgh EH9 3HJ (United Kingdom); Hayward, Thomas L., E-mail: jrmales@as.arizona.edu [Gemini Observatory, Southern Operations Center, c/o AURA, Casilla 603, La Serena (Chile); and others

    2014-05-01

    We present the first ground-based CCD (λ < 1 μm) image of an extrasolar planet. Using the Magellan Adaptive Optics system's VisAO camera, we detected the extrasolar giant planet β Pictoris b in Y-short (Y{sub S} , 0.985 μm), at a separation of 0.470 ± 0.''010 and a contrast of (1.63 ± 0.49) × 10{sup –5}. This detection has a signal-to-noise ratio of 4.1 with an empirically estimated upper limit on false alarm probability of 1.0%. We also present new photometry from the Gemini Near-Infrared Coronagraphic Imager instrument on the Gemini South telescope, in CH {sub 4S,1%} (1.58 μm), K{sub S} (2.18 μm), and K {sub cont} (2.27 μm). A thorough analysis of our photometry combined with previous measurements yields an estimated near-IR spectral type of L2.5 ± 1.5, consistent with previous estimates. We estimate log (L {sub bol}/L {sub ☉}) = –3.86 ± 0.04, which is consistent with prior estimates for β Pic b and with field early-L brown dwarfs (BDs). This yields a hot-start mass estimate of 11.9 ± 0.7 M {sub Jup} for an age of 21 ± 4 Myr, with an upper limit below the deuterium burning mass. Our L {sub bol}-based hot-start estimate for temperature is T {sub eff} = 1643 ± 32 K (not including model-dependent uncertainty). Due to the large corresponding model-derived radius of R = 1.43 ± 0.02 R {sub Jup}, this T {sub eff} is ∼250 K cooler than would be expected for a field L2.5 BD. Other young, low-gravity (large-radius), ultracool dwarfs and directly imaged EGPs also have lower effective temperatures than are implied by their spectral types. However, such objects tend to be anomalously red in the near-IR compared to field BDs. In contrast, β Pic b has near-IR colors more typical of an early-L dwarf despite its lower inferred temperature.

  9. Efficiency of different breathing filters on peak inspiratory pressure in mechanical ventilation%不同呼吸过滤器在机械通气中对气道峰压的影响

    Institute of Scientific and Technical Information of China (English)

    李璐; 赵砚丽; 韩广彦

    2008-01-01

    Objective To comprehensively evaluate the influence on peak inspiratory pressure(PIP)in mechanical ventilation.Methods Sixty patients,aged 18-65 years old,operating time about three hours,who underwent elective abdominal surgery in general anesthesia were enrolled.All patients had no breathing system diseases and heart failure diseases.All patients were randomly divided into four groups(n=15):PALL BB 25S(P)group,DAR 352/5805(D)group,Vital signs 5702 TMP(V1)group and Vital signs 5708 HEPA(V2)group.PIP scale was recorded at five minutes before applying BF,five minutes after applying BF and the finishing time of operation.Results There was no significant difference among four groups at the different time(P>0.05).But at the t2 and t3 time,the value of PIP was higher than its former time in the same group(P<0.05).Conclusions Using breathing filter has little influence on PIP.But its change is permitted in clinical practice.%目的 综合性评价不同类型呼吸过滤器(breathing filter,BF)在机械通气中对气道峰压(peak inspiratory pressure,PIP)的影响.方法 选择择期全麻下行腹部手术患者60例,年龄18~65 岁,手术时间约3 h,既往无呼吸系统疾患及心力衰竭病史,随机分为4组(每组15例):PALL BB 25S(P)组、DAR 352/5805(D)组、Vital signs 5702 TMP(V1)组和Vital signs 5708 HEPA(V2)组,记录应用BF前5 min (t1)、应用BF后5 min(t2)及术毕即刻(t3)时的PIP值.结果 4组在同一时点比较中PIP值差异无统计学意义(P>0.05);4组组内t2与t1时刻比较以及t3与t2时刻比较PIP值升高差异均有统计学意义(P<0.05).结论 在机械通气中使用呼吸过滤器会增加一定程度的PIP,但PIP的实际测量值均在临床允许范围之内.

  10. Differential Responses to Simulated Precipitation Exhibited by a Typical Shrub and a Herb Coexisted in Hunshandak Sandy Land%浑善达克沙地典型灌木和草本植物对模拟降雨的不同反应

    Institute of Scientific and Technical Information of China (English)

    牛书丽; 彭羽; 蒋高明; 李永庚; 高雷鸣; 刘美珍; 崔洪霞; 丁莉

    2004-01-01

    为了探讨不同生活型对瞬时降雨的适应策略,比较了浑善达克沙地常见灌木羊柴(Hedysarum fruticosum Pall.)和其共生草本植物猪毛菜(Salsola callina Y.L. Chang)在降雨解除干旱后的生理生态反应.光合速率(Pn)、蒸腾速率(E)、气孔导度(gs)、PSⅡ最大光化学效率(Fv/Fm)和叶片水势(ψleaf)均随着模拟降雨量的增加而增大;羊柴的水分利用效率(WUE)随降雨量的变化不大,而猪毛菜的WUE却随降雨量的增加一直处于下降趋势.两种植物的Pn和Fv/Fm都在雨后3 d完全恢复,而gs和ψleaf却提前1或2 d恢复,这说明气孔和非气孔因素综合限制了羊柴和猪毛菜的同化速率.两种植物对模拟降雨量的反应方式不同,15 mm的雨量就使羊柴的Pn、E和gs达到最大值,而猪毛菜却随着雨量的增加一直增大.我们认为,羊柴和猪毛菜对于模拟降雨的反应在时间上具有同步性,但对雨量的反应方式却不一致,猪毛菜对水分的利用不经济且瞬时反应,而羊柴可以被认为是节约型用水植物.%To assess the ecophysiological responses and adaptive strategies to rainfall exhibited by different plant functional types, we compared gas exchange, leaf water potential (ψleaf) and PSⅡ photochemical efficiency (Fv/Fm) between Hedysarum fruticosum Pall. (shrub) and Salsola collina Y. L. Chang (herb) under a series of simulated rainfalls. The experiment was conducted in Hunshandak Sandy Land,North China. The values of net photosynthetic rate (Pn), transpiration rate (E), stomatai conductance (gs),Fv/Fm and ψleaf always elevated with the increasing amount of simulated rainfall. Whereas water use efficiency (WUE) maintained constant in /. fruticosum while always decreased in S. collina. Both species fully recovered their Pn and Fv/Fm 3 d after rainfall, while gs and ψleaf recovered only within 2 d. However,the response patterns were obviously different.H. fruticosu promote its physiological traits within 5

  11. Distribution of natural disturbance due to wave and tidal bed currents around the UK

    Science.gov (United States)

    Bricheno, Lucy M.; Wolf, Judith; Aldridge, John

    2015-10-01

    The UK continental shelf experiences large tidal ranges and winter storm events, which can both generate strong near-bed currents. The regular tidal bottom currents from tides plus wind driven 'benthic storms' (dominated by wave-driven oscillatory currents in shallow water) are a major source of disturbance to benthic communities, particularly in shallow waters. We aim to identify and map the relative impact of the tides and storm events on the shallower parts of the North West European continental shelf. A 10-year simulation of waves, tides and surges on the continental shelf was performed. The shelf model was validated against current meter observations and the Centre for Environmental, Fisheries and Aquaculture Science (CEFAS) network of SmartBuoys. Next, the model performance was assessed against seabed lander data from two sites in the Southern North Sea; one in deep water and another shallow water site at Sea Palling, and a third in Liverpool Bay. Both waves and currents are well simulated at the offshore Southern North Sea site. A large storm event was also well captured, though the model tends to underpredict bottom orbital velocity. Poorer results were achieved at the Sea Palling site, thought to be due to an overly deep model water depth, and missing wave-current interactions. In Liverpool Bay tides were well modelled and good correlations (average R2=0.89) are observed for significant wave height, with acceptable values (average R2=0.79) for bottom orbital velocity. Using the full 10-year dataset, return periods can be calculated for extreme waves and currents. Mapping these return periods presents a spatial picture of extreme bed disturbance, highlighting the importance of rare wave disturbances (e.g. with a return period of 1 in 10 years). Annual maximum currents change little in their magnitude and distribution from year to year, with mean speeds around 0.04 m s-1, and maximums exceeding 3 m s-1. Wave conditions however are widely variable throughout

  12. Preliminary field evaluation of high efficiency steel filters

    International Nuclear Information System (INIS)

    The authors have conducted an evaluation of two high efficiency steel filters in the exhaust of an uranium oxide grit blaster at the Y-12 Plant in Oak Ridge Tennessee. The filters were installed in a specially designed filter housing with a reverse air-pulse cleaning system for automatically cleaning the filters in-place. Previous tests conducted on the same filters and housing at LLNL under controlled conditions using Arizona road dust showed good cleanability with reverse air pulses. Two high efficiency steel filters, containing 64 pleated cartridge elements housed in the standard 2' x 2' x l' HEPA frame, were evaluated in the filter test housing using a 1,000 cfm slip stream containing a high concentration of depleted uranium oxide dust. One filter had the pleated cartridges manufactured to the authors specifications by the Pall Corporation and the other by Memtec Corporation. Test results showed both filters had a rapid increase in pressure drop with time, and reverse air pulses could not decrease the pressure drop. The authors suspected moisture accumulation in the filters was the problem since there were heavy rains during the evaluations, and the pressure drop of the Memtec filter decreased dramatically after passing clean, dry air through the filter and after the filter sat idle for one week. Subsequent laboratory tests on a single filter cartridge confirmed that water accumulation in the filter was responsible for the increase in filter pressure drop and the inability to lower the pressure drop by reverse air pulses. No effort was made to identify the source of the water accumulation and correct the problem because the available funds were exhausted

  13. The effects of refraction on transit transmission spectroscopy: application to Earth-like exoplanets

    Energy Technology Data Exchange (ETDEWEB)

    Misra, Amit; Meadows, Victoria [Astronomy Department, University of Washington, Box 351580, Seattle, WA 98195 (United States); Crisp, Dave, E-mail: amit0@astro.washington.edu [NAI Virtual Planetary Laboratory, Seattle, WA (United States)

    2014-09-01

    We quantify the effects of refraction in transit transmission spectroscopy on spectral absorption features and on temporal variations that could be used to obtain altitude-dependent spectra for planets orbiting stars of different stellar types. We validate our model against altitude-dependent transmission spectra of the Earth from ATMOS and against lunar eclipse spectra from Pallé et al. We perform detectability studies to show the potential effects of refraction on hypothetical observations of Earth analogs with the James Webb Space Telescope NIRSPEC. Due to refraction, there will be a maximum tangent pressure level that can be probed during transit for each given planet-star system. We show that because of refraction, for an Earth-analog planet orbiting in the habitable zone of a Sun-like star only the top 0.3 bars of the atmosphere can be probed, leading to a decrease in the signal-to-noise ratio (S/N) of absorption features by 60%, while for an Earth-analog planet orbiting in the habitable zone of an M5V star it is possible to probe almost the entire atmosphere with minimal decreases in S/N. We also show that refraction can result in temporal variations in the transit transmission spectrum which may provide a way to obtain altitude-dependent spectra of exoplanet atmospheres. Additionally, the variations prior to ingress and subsequent to egress provide a way to probe pressures greater than the maximum tangent pressure that can be probed during transit. Therefore, probing the maximum range of atmospheric altitudes, and in particular the near-surface environment of an Earth-analog exoplanet, will require looking at out-of-transit refracted light in addition to the in-transit spectrum.

  14. Preliminary field evaluation of high efficiency steel filters

    International Nuclear Information System (INIS)

    We have conducted an evaluation of two high efficiency steel filters in the exhaust of an uranium oxide grit blaster at the Y-12 Plant in Oak Ridge Tennessee. The filters were installed in a specially designed filter housing with a reverse air-pulse cleaning system for automatically cleaning the filters in-place. Previous tests conducted on the same filters and housing at LLNL under controlled conditions using Arizona road dust showed good cleanability with reverse air pulses. Two high efficiency steel filters, containing 64 pleated cartridge elements housed in the standard 2' x 2' x 1' HEPA frame, were evaluated in the filter test housing using a 1,000 cfm slip stream containing a high concentration of depleted uranium oxide dust. One filter had the pleated cartridges manufactured to our specifications by the Pall Corporation and the other by Memtec Corporation. Test results showed both filters had a rapid increase in pressure drop with time, and reverse air pulses could not decrease the pressure drop. We suspected moisture accumulation in the filters was the problem since there were heavy rains during the evaluations, and the pressure drop of the Memtec filter decreased dramatically after passing clean, dry air through the filter and after the filter sat idle for one week. Subsequent laboratory tests on a single filter cartridge confirmed that water accumulation in the filter was responsible for the increase in filter pressure drop and the inability to lower the pressure drop by reverse air pulses. No effort was made to identify the source of the water accumulation and correct the problem because the available funds were exhausted

  15. Estimation of thyroid gland state of voles natural populations from increased radioactive background territories

    International Nuclear Information System (INIS)

    Investigation of effects caused in biological objects by chronic low-intensity radiation in their natural habitats is one of the most important problems of modern radioecology. The aim of our work - complex estimation of state of thyroid gland of voles inhabiting increased radioactive background territories. We investigated tundra voles (Microtus oeconomus Pall.) that were sampled at different stages of population cycle from the experimental and the control sites in the Uhta region of the Komi Republic, Russia. Experimental site contamination resulted from commercial extraction od radium between the 1930's and 1950's. Irradiation exposure dose at the site was 50-2000 mR/h (at the control site 10-15 mR/h). Complex estimation of thyroid was made by histological, morpho-metrical, radioimmunological and cytogenetic methods. Results showed high sensitivity of thyroid gland of tundra voles from chronically irradiated natural populations. We found reliable changes in morphological features of thyroid, in the level of thyroidal hormones and increased frequency of cells with micro-nucleuses in animals sampled from the experimental site as compared with the control ones. It was also showed, that chronic exposure of ionizing irradiation at the same range of absorbed doses can cause different effects in animals depending on sex, age and the stage of population cycle. This confirms the need of including these biological factors to analysis of low doses effects in the natural populations during radioecological studies. Investigations were supported by RFBR grants No. 13-04-01750? and No. 13-04-90351-RBUa. Document available in abstract form only. (authors)

  16. Root distribution of three co-occurring desert shrubs and their physiological response to precipitation

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Root distribution of three desert shrubs,Tamarix ramosissima Ledeb.,Haloxylon ammodendron(C.A.Mey.) Bunge and Reaumuria soongorica(Pall.) Maxim.was investigated under co-occurring conditions using a method for excavating the whole root system.Assimilation shoot water potential and transpiration rates were monitored during the wet-dry cycle.Leaf-specific apparent hydraulic conductance and the index of water stress impact for the three species were calculated from shoot water potential and transpiration rate.The results showed that,along the soil profile,the root system of T.ramosissima mainly distributed at 50 to 310 cm interval,with an average total absorbing root-surface area of 30,249.2 cm2 per plant;the root system of H.ammodendraom distributed at 0 to 250 cm interval with an average total absorbing root-surface area of 12,847.3 cm2 per plant;the root system of R.soongorica distributed at 0-80 cm interval,with an average total absorbing root-surface area of 361.8 cm2.The root distribution shows the following:T.ramosissima uses groundwater as its main water source;H.ammodendraom uses both groundwater and rainwater;and R.soongorica uses rainwater only.During the wet-dry cycle,the hydraulic parameters of T.ramosissima showed no responses to precipitation.R.soongorica responded most significantly,and the responses of H.ammodendraom were intermediate.In conclusion,the plant response to rain events is closely related to their root distribution and plant water-use strategy.

  17. Protective mechanism of desiccation tolerance in Reaumuria soongorica: Leaf abscission and sucrose accumulation in the stem

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Reaumuria soongorica (Pall.) Maxim., a perennial semi-shrub, is widely found in semi-arid areas in northwestern China and can survive severe desiccation of its vegetative organs. In order to study the protective mechanism of desiccation tolerance in R. soongorica, diurnal patterns of net photosynthetic rate (Pn), water use efficiency (WUE) and chlorophyll fluorescence parameters of Photosystem II (PSII), and sugar content in the source leaf and stem were investigated in 6-year-old plants during progressive soil drought imposed by the cessation of watering. The results showed that R. soongorica was char-acterized by very low leaf water potential, high WUE, photosynthesis and high accumulation of sucrose in the stem and leaf abscission under desiccation. The maximum Pn increased at first and then de-clined during drought, but intrinsic WUE increased remarkably in the morning with increasing drought stress. The maximal photochemical efficiency of PSII (Fv/Fm) and the quantum efficiency of noncyclic electric transport of PSII(ΦPSII) decreased significantly under water stress and exhibited an obvious phenomenon of photoinhibition at noon. Drought stressed plants maintained a higher capacity of dis-sipation of the excitation energy (measured as NPQ) with the increasing intensity of stress. Conditions of progressive drought promoted sucrose and starch accumulation in the stems but not in the leaves. However, when leaf water potential was less than –21.3 MPa, the plant leaves died and then abscised. But the stem photosynthesis remained and, afterward the plants entered the dormant state. Upon re-watering, the shoots reactivated and the plants developed new leaves. Therefore, R. soongorica has the ability to reduce water loss through leaf abscission and maintain the vigor of the stem cells to survive desiccation.

  18. Protective mechanism of desiccation tolerance in Reaumuria soongorica: Leaf abscission and sucrose accumulation in the stem

    Institute of Scientific and Technical Information of China (English)

    LIU YuBing; ZHANG TengGuo; LI XingRong; WANG Gang

    2007-01-01

    Reaumuria soongorica (Pall.) Maxim., a perennial semi-shrub, is widely found in semi-arid areas in northwestern China and can survive severe desiccation of its vegetative organs. In order to study the protective mechanism of desiccation tolerance in R. Soongorica, diurnal patterns of net photosynthetic rate (Pn), water use efficiency (WUE) and chlorophyll fluorescence parameters of Photosystem II (PSII), and sugar content in the source leaf and stem were investigated in 6-year-old plants during progressive soil drought imposed by the cessation of watering. The results showed that R. Soongorica was characterized by very low leaf water potential, high WUE, photosynthesis and high accumulation of sucrose in the stem and leaf abscission under desiccation. The maximum Pn increased at first and then declined during drought, but intrinsic WUE increased remarkably in the morning with increasing drought stress. The maximal photochemical efficiency of PSII (Fv/Fm) and the quantum efficiency of noncyclic electric transport of PSII(Φpsii) decreased significantly under water stress and exhibited an obvious phenomenon of photoinhibition at noon. Drought stressed plants maintained a higher capacity of dissipation of the excitation energy (measured as NPQ) with the increasing intensity of stress. Conditions of progressive drought promoted sucrose and starch accumulation in the stems but not in the leaves. However, when leaf water potential was less than -21.3 Mpa, the plant leaves died and then abscised. But the stem photosynthesis remained and, afterward the plants entered the dormant state. Upon rewatering, the shoots reactivated and the plants developed new leaves. Therefore, R. Soongorica has the ability to reduce water loss through leaf abscission and maintain the vigor of the stem cells to survive desiccation.

  19. Aerobic desulfurization of biogas by acidic biotrickling filtration in a randomly packed reactor

    International Nuclear Information System (INIS)

    Highlights: • Desulfurization of high loads of H2S is feasible by acidic biotrickling filtration. • Robustness of the process is demonstrated in the long-term (550 d). • Biosulfur to sulfate oxidation under H2S starvation was successfully performed. • Lower sulfate production found at acidic pH compared to that at neutral pH. • Plastic material is recommended for long-term acidic biotrickling filtration. - Abstract: Biotrickling filters for biogas desulfurization still must prove their stability and robustness in the long run under extreme conditions. Long-term desulfurization of high loads of H2S under acidic pH was studied in a lab-scale aerobic biotrickling filter packed with metallic Pall rings. Reference operating conditions at steady-state corresponded to an empty bed residence time (EBRT) of 130 s, H2S loading rate of 52 g S–H2S m−3 h−1 and pH 2.50–2.75. The EBRT reduction showed that the critical EBRT was 75 s and the maximum EC 100 g S–H2S m−3 h−1. Stepwise increases of the inlet H2S concentration up to 10,000 ppmv lead to a maximum EC of 220 g S–H2S m−3 h−1. The H2S removal profile along the filter bed indicated that the first third of the filter bed was responsible for 70–80% of the total H2S removal. The oxidation rate of solid sulfur accumulated inside the bioreactor during periodical H2S starvation episodes was verified under acidic operating conditions. The performance under acidic pH was comparable to that under neutral pH in terms of H2S removal capacity. However, bioleaching of the metallic packing used as support and chemical precipitation of sulfide/sulfur salts occurred

  20. Actitud del estudiante de ingeniería hacia sus errores en el aprendizaje de la matemática

    Directory of Open Access Journals (Sweden)

    Lissette Franchi Boscán

    2011-09-01

    Full Text Available Bajo cualquier esquema de enseñanza-aprendizaje de la matemática, cuando al alumno se le señalan errores en su trabajo, puede, en general, adoptar tres tipos de actitud: una actitud negativa, bajo la cual el alumno considera que sus errores son sencillamente un síntoma de su fracaso; una actitud neutra o indiferente ante sus errores; o una actitud positiva, considerándolos como un medio para aprender y planteándose como reto el superarlos. Este artículo muestra una investigación que abordó el estudio de actitudes vinculadas al proceso de aprendizaje de la matemática. Su objetivo fue describir la actitud que el estudiante de ingeniería de la Uni- versidad del Zulia exhibe frente a sus errores cuando aprende matemática. La sus tentación teórica se baso en Brousseau (2001, Briñol et al. (2007 y los autores Pallí y Martínez (2004. Se utilizó una escala AEAM (Actitud hacia el Error del Alumno de Matemática, tipo Likert con 6 alternativas de respuesta que consta de 36 ítems, en su segunda versión, actualizada por los autores. El instrumento fue validado mediante juicio de expertos y se determinó que era de alta confiabilidad, con un alpha de Cronbach de 0.9073. Se concluyó que los participantes, en su mayoría, mostraron una actitud moderadamente positiva hacia sus errores, que al no estar ubicada en el extremo positivo deseable refleja una actitud débil que no garantiza una conducta adecuada hacia los errores, pero que sin embargo es sus ceptible de ser mejorada hacia una actitud francamente positiva.

  1. Identification of differentially expressed genes in leaf of Reaumuria soongorica under PEG-induced drought stress by digital gene expression profiling.

    Science.gov (United States)

    Liu, Yubing; Liu, Meiling; Li, Xinrong; Cao, Bo; Ma, Xiaofei

    2014-01-01

    Reaumuria soongorica (Pall.) Maxim., a resurrection semi-shrub, is a typical constructive and dominant species in desert ecosystems in northwestern China. However, the gene expression characteristics of R. soongorica under drought stress have not been elucidated. Digital gene expression analysis was performed using Illumina technique to investigate differentially expressed genes (DEGs) between control and PEG-treated samples of R. soongorica. A total of 212,338 and 211,052 distinct tags were detected in the control and PEG-treated libraries, respectively. A total of 1,325 genes were identified as DEGs, 379 (28.6%) of which were up-regulated and 946 (71.4%) were down-regulated in response to drought stress. Functional annotation analysis identified numerous drought-inducible genes with various functions in response to drought stress. A number of regulatory proteins, functional proteins, and proteins induced by other stress factors in R. soongorica were identified. Alteration in the regulatory proteins (transcription factors and protein kinase) may be involved in signal transduction. Functional proteins, including flavonoid biosynthetic proteins, late embryogenesis abundant (LEA) proteins, small heat shock proteins (sHSP), and aquaporin and proline transporter may play protective roles in response to drought stress. Flavonoids, LEA proteins and sHSP function as reactive oxygen species scavenger or molecular chaperone. Aquaporin and proline transporters regulate the distribution of water and proline throughout the whole plant. The tolerance ability of R. soongorica may be gained through effective signal transduction and enhanced protection of functional proteins to reestablish cellular homeostasis. DEGs obtained in this study may provide useful insights to help further understand the drought-tolerant mechanism of R. soongorica. PMID:24736242

  2. Identification of differentially expressed genes in leaf of Reaumuria soongorica under PEG-induced drought stress by digital gene expression profiling.

    Directory of Open Access Journals (Sweden)

    Yubing Liu

    Full Text Available Reaumuria soongorica (Pall. Maxim., a resurrection semi-shrub, is a typical constructive and dominant species in desert ecosystems in northwestern China. However, the gene expression characteristics of R. soongorica under drought stress have not been elucidated. Digital gene expression analysis was performed using Illumina technique to investigate differentially expressed genes (DEGs between control and PEG-treated samples of R. soongorica. A total of 212,338 and 211,052 distinct tags were detected in the control and PEG-treated libraries, respectively. A total of 1,325 genes were identified as DEGs, 379 (28.6% of which were up-regulated and 946 (71.4% were down-regulated in response to drought stress. Functional annotation analysis identified numerous drought-inducible genes with various functions in response to drought stress. A number of regulatory proteins, functional proteins, and proteins induced by other stress factors in R. soongorica were identified. Alteration in the regulatory proteins (transcription factors and protein kinase may be involved in signal transduction. Functional proteins, including flavonoid biosynthetic proteins, late embryogenesis abundant (LEA proteins, small heat shock proteins (sHSP, and aquaporin and proline transporter may play protective roles in response to drought stress. Flavonoids, LEA proteins and sHSP function as reactive oxygen species scavenger or molecular chaperone. Aquaporin and proline transporters regulate the distribution of water and proline throughout the whole plant. The tolerance ability of R. soongorica may be gained through effective signal transduction and enhanced protection of functional proteins to reestablish cellular homeostasis. DEGs obtained in this study may provide useful insights to help further understand the drought-tolerant mechanism of R. soongorica.

  3. Preliminary field evaluation of high efficiency steel filters

    Energy Technology Data Exchange (ETDEWEB)

    Bergman, W.; Larsen, G.; Lopez, R. [Lawrence Livermore National Laboratory, CA (United States)] [and others

    1995-02-01

    We have conducted an evaluation of two high efficiency steel filters in the exhaust of an uranium oxide grit blaster at the Y-12 Plant in Oak Ridge Tennessee. The filters were installed in a specially designed filter housing with a reverse air-pulse cleaning system for automatically cleaning the filters in-place. Previous tests conducted on the same filters and housing at LLNL under controlled conditions using Arizona road dust showed good cleanability with reverse air pulses. Two high efficiency steel filters, containing 64 pleated cartridge elements housed in the standard 2` x 2` x 1` HEPA frame, were evaluated in the filter test housing using a 1,000 cfm slip stream containing a high concentration of depleted uranium oxide dust. One filter had the pleated cartridges manufactured to our specifications by the Pall Corporation and the other by Memtec Corporation. Test results showed both filters had a rapid increase in pressure drop with time, and reverse air pulses could not decrease the pressure drop. We suspected moisture accumulation in the filters was the problem since there were heavy rains during the evaluations, and the pressure drop of the Memtec filter decreased dramatically after passing clean, dry air through the filter and after the filter sat idle for one week. Subsequent laboratory tests on a single filter cartridge confirmed that water accumulation in the filter was responsible for the increase in filter pressure drop and the inability to lower the pressure drop by reverse air pulses. No effort was made to identify the source of the water accumulation and correct the problem because the available funds were exhausted.

  4. Effect of Traditional Chinese Medicine Complex for diabetes (TCM-D™ on experimentally induced diabetic mice

    Directory of Open Access Journals (Sweden)

    Donald Koh Fook Chen

    2013-03-01

    Full Text Available Background: We previously evaluated the biochemicalchanges induced by the local product TCM fordiabetes (TCM-D™ on blood glucose levels and otherbiochemical changes in normal mice fed orally with therecommended human dose (30 ml/kg daily and tentimes this dose for eight weeks. TCM-D™ is an aqueousextract of the roots of Trichosanthes kirilowii Maxim,Paeonia lactiflora Pall, Glycyrrhiza uranlensis Fisch. andPanax ginseng Meyer (red combined at the dry weightproportions of 36%, 28%, 18% and 18% respectively.The study showed that at these dosages the bloodglucose levels as well as the body weights in treated micewere significantly reduced when compared with pretreatmentvalues and control animals. The present studyevaluated the effect of the extract in a mouse model ofType 1 diabetes mellitus.Methods: TCM-D™ extract was prepared as a 10xconcentrate and given orally at 0.3 ml/100 g and1.5 ml/100 g to mice which were experimentallyinduced diabetic with intraperitoneal injections ofstreptozotocin (5 mg/100g in sodium citrate (pH 4.5.Control diabetic mice were dosed with extract diluent(distilled water.Results: At the doses studied the compound did notshow any significant lowering of the glucose levels in amouse model of Type 1 diabetes. There were significantincreases in the alanine aminotransferase (ALT andcreatinine levels which were most likely due to thetreatment with the compound. There were no significantchanges in the aspartate aminotransferase (AST andblood urea levels due to the treatment. Neither wasthere any significant effect on the weight of the treatedanimals due to the treatment.Conclusions: It is concluded that TCM-D™ did nothave any significant blood glucose lowering effect onstreptozotocin induced diabetic mice when fed orally at1-5 times the recommended human dose. Further workis needed to determine if the extract has any significanteffect in a mouse model with Type 2 diabetes mellitus.

  5. Soil carbon sequestration by three perennial legume pastures is greater in deeper soil layers than in the surface soil

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    X.-K. Guan

    2015-07-01

    Full Text Available Soil organic carbon (SOC plays a vital role as both a sink for and source of atmospheric carbon. Revegetation of degraded arable land in China is expected to increase soil carbon sequestration, but the role of perennial legumes on soil carbon stocks in semiarid areas has not been quantified. In this study, we assessed the effect of alfalfa (Medicago sativa L. and two locally adapted forage legumes, bush clover (Lespedeza davurica S. and milk vetch (Astragalus adsurgens Pall. on the SOC concentration and SOC stock accumulated annually over a 2 m soil profile, and to estimate the long-term potential for SOC sequestration in the soil under the three forage legumes. The results showed that the concentration of SOC of the bare soil decreased slightly over the 7 years, while 7 years of legume growth substantially increased the concentration of SOC over the 0–2.0 m soil depth measured. Over the 7 year growth period the SOC stocks increased by 24.1, 19.9 and 14.6 Mg C ha−1 under the alfalfa, bush clover and milk vetch stands, respectively, and decreased by 4.2 Mg C ha−1 under bare soil. The sequestration of SOC in the 1–2 m depth of soil accounted for 79, 68 and 74 % of SOC sequestered through the upper 2 m of soil under alfalfa, bush clover and milk vetch, respectively. Conversion of arable land to perennial legume pasture resulted in a significant increase in SOC, particularly at soil depths below 1 m.

  6. The phenology of flowering and fluctuations of airborne pollen concentrations of selected trees in Poznań, 2003-2004

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    Alicja Stach

    2012-12-01

    Full Text Available The aim of the study was to describe the relationships between the flowering phase of selected tree species, whose pollen is known to be allergenic, and fluctuations in the pollen in the air, and to use results obtained for making allergological forecasts. Studies were conducted of five tree taxa: Populus, Ulmus, Salix, Aesculus, and Tilia, in the years 2003-2004. Aeropalinological analyses concerned the above mentioned genera, while in phenological studies specific species were investigated, i.e. the most common representatives of a given genus found in Poland, that is Populus wilsonii, Ulmus laevis Pall. C. K.Schneid., Salix caprea L., Aesculus hippocastanum L. and Tilia cordata Mill. Aerobiological monitoring was performed using a the volumetric method and phenological observations of flowering phases were made according to the Łukasiewicz method. While observing the emergence of individual phenological symptoms and measurements of the concentration of pollen of the investigated taxa in the air of Poznań, a distinct acceleration was observed in 2004, a year that was characterized by a milder winter. This applied not only to the species blooming in early spring, but also to the later ones. Pollen grains of the investigated taxa, except for Aesculus, appeared earlier in aeropalinological observations than the macroscopically observed beginning of flowering in selected trees. Apart from a poplar, the end of flowering in the other trees occurred each year earlier than would follow from the aerobiological observations. This may be explained by the abundance of species within a taxon, and the effect of medium - and long-distance transport.

  7. The effect of natural and planted forest stands on soil fertility in the Hyrcanian region, Iran

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    RAZIYEH RAFEIE JAHED

    2014-10-01

    Full Text Available Rafeie Jahed R, Hosseini SM, Kooch Y. 2014. The effect of natural and planted forest stands on soil fertility in the Hyrcanian region, Iran. Biodiversitas 15: 206-214. In the present work, we studied the effect of natural and planted forest stands on soil fertility in the Hyrcanian region of northern Iran. Natural forest stands (including Acer velutinum Bioss., Zelkova carpinifolia (Pall, Parrotia persica (DC. C.A.Mey, Quercus castaneifolia C.A. Mey., Carpinus betulus L, Mixed planted stand (including Acer velutinum, Ulmus carpinifolia G. Suckow Quercus castaneifolia C.A. Mey, Carpinus betulus L., Tilia begonifolia Scop. Subsp. caucasia (Rupr. Loria; maple (Acer velutinum Bioss plantation, pine (Pinus taeda L. plantation and also clear-cut region (control were considered in this research. Soil samples were collected at two different depths, i.e., 0-15 and 15-30 cm, and characterized with respect to organic carbon (C, total nitrogen (N, available nutrient elements (P, K, Ca and Mg; pH and soil texture. The results showed that the highest amount of total N was found in mixed plantation. The highest amount of available P was detected in maple plantation and pine plantation had the highest available K and organic C than other treatments. The highest and the lowest available Ca and Mg were found in natural forest and control area, respectively. In addition, it was observed that nutrients accumulate in upper layers of the soil. Hardwood stands have been more successful than the conifers stands, so this should be considered in the sustainable management of forests.

  8. Invasive Ponto-Caspian hydrozoan Cordylophora caspia (hydrozoa: Cnidaria) in southern Baltic coastal lakes

    Science.gov (United States)

    Obolewski, Krystian; Jarosiewicz, Anna; Ożgo, Małgorzata

    2015-12-01

    Cordylophora caspia Pall. is a highly invasive Ponto-Caspian colonial hydroid with a worldwide distribution. It is a biofouling organism colonizing industrial water installations and causing serious economic problems. Here, we give the first report of its occurrence in southern Baltic coastal lakes, and analyze its distribution in relation to environmental factors and likely colonization routes. Samples were collected from the stalks of Phragmites australis at the total of 102 sites in 15 lakes and lagoons. The species was most numerous in lagoons, i.e. ß-oligohaline water bodies with a surface hydrological connection with the sea, where it reached mean densities of 1200-4800 hydranths m-2. In regression tree analysis, chloride concentration, followed by pH, were the strongest explanatory variables for its occurrence, with highest densities observed at chloride concentration above 1.18 g Cl L-1 and pH 8.05-9.26. At pH 5.77-8.04 higher densities were observed at temperatures above 20.3 °C. Generally, within the range of parameters observed in our study, high densities of C. caspia were associated with high chloride concentration, pH, temperature and electrical conductivity values. The species was also present in freshwater lakes; these colonies may have the highest capacity for future invasions of such habitats. Within lakes, high densities were observed at canals connecting these water bodies with the sea, and at sites close to the inflow of rivers. This distribution pattern can facilitate its further spread into inland waters.

  9. Content of sodium ions in the tissues of Crimean flora halophytes depending on the varying degree of salinity

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    S. N. Kabuzenko

    2015-03-01

    Full Text Available The quantitative content and distribution in organs and tissue compartments of Na+ ions in halophytes Suaeda prostrata Pall., Salicornia perennans Willd., Artemisia santonica L. growing in the areas with chloride-sulfate type of salinization of soil in the vicinity of the Sasyk salt lake (Northwest Crimea has been determined. It was found that for S. perennans and S. prostrata euhalophytes the strategy of translocation of Na+ ions to the organs of the aerial part with increasing NaCl concentration in the medium was typical. In this case, the content of Na+ ions in the cell sap of the above-ground parts of plants significantly increases which is more pronounced in S. perennans. Increasing concentrations of NaCl in the medium contribute to 0.50–0.75% improvement in plant growth indicators and protein content increase in vegetative organs. A positive correlation between the content of Na+ and biomass accumulation in organs of euhalophytes is shown. Glycohalophyte A. santonica is characterized by localization of Na+ ions predominantly in the root tissues. The highest content of Na+ ions in the above-ground organs of euhalophytes growing in natural conditions was observed in the phase of active vegetative growth and budding, therefore, it is recommended to mow their aerial organs at these stages of ontogenesis for the purpose of soil desalinization. It is concluded that absorption of Na+, as a strategy of adaptation of halophytes to salinity, not only helps to reduce water potential in cells and plants in general, but also activates anabolism, which directly correlates with their salt tolerance.

  10. A meta-analysis of bevacizumab combined with chemotherapy in the treatment of ovarian cancer

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    T S Wang

    2014-01-01

    Full Text Available Introduction: Angiogenesis plays an important role in the biology of ovarian cancer. The clinical efficacy and side effects of bevacizumab, the vascular endothelial growth factor inhibitor, on survival and toxicity in women with this ovarian cancer, was not conclusive. We performed this systematic review and meta-analysis in order to clarify the efficacy of bevacizumab combined with chemotherapy in the treatment of ovarian cancer. Materials and Methods: We searched the electronic database of MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials and CNKI for clinical controlled trials of comparing bevacizumab combined with chemotherapy and chemotherapy alone in the treatment of ovarian cancer. The primary outcomes of eligible studies included median progression-free survival (PFS, overall survival (OS, and toxicities such as enterobrosis, hypertension, albuminuria, congestive heart failure (CHF, neutrophils, thrombosis, and bleeding. The Hazard ratio (HR and relative risk were used for the meta-analysis and were expressed with 95% confidence intervals (CIs. All the statistical analyses were carried out by  Stata 11.0 software (http://www.stata.com; Stata Corporation, College Station, TX, USA. Results: We included 5 studies with 1798 cases in the bevacizumab combined with the chemotherapy group and 1810 subjects in the chemotherapy alone group. The pooled results showed that bevacizumab + chemotherapy compared with chemotherapy alone can significant prolong the median PFS (HR, 0.64; 95% CI, 0.46-0.82; P 0.05; the toxicity analysis showed that the enterobrosis, hypertension, albuminuria, neutrophils, thrombosis, and bleeding were significantly increased in the bevacizumab + chemotherapy group compared with chemotherapy alone (Pall 0.05. Conclusion: Bevacizumab combined with chemotherapy prolonged the median PFS in patients with ovarian cancer but also increase the risk of developing enterobrosis, hypertension, albuminuria, neutrophils

  11. Book Reviews

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    Redactie KITLV

    1971-04-01

    Full Text Available - A.H.N. Verwey, A.J. Bernet Kempers, Borobudur: Mysteriegebeuren in steen, Verval en restauratie, Oudjavaans volksleven. Servire, Wassenaar 1970. 224 blz., 280 afb. - Graham W. Irwin, Anthony Reid, The contest for North Sumatra. Atjeh, the Netherlands and Britain 1858-1898. Kuala Lumpur and London: University of Malaya Press and Oxford University Press, 1969. 333 p., 8 plates, maps. - John Bastin, Fernand Mendes Pinto, The voyages and adventures of Fernand Mendez Pinto: Translated into English by H. Cogan 1635. Dawsons of Pall Mall. The Colonial History Series, General Editor, D.H. Simpson. London, 1969. Pages xiv + 318. - R. Roolvink, Yahya Ismail, Satu kajian mengenai karya2 Ahmad Talu. Dewan Bahasa dan Pustaka, Kuala Lumpur, 1970. XIV + 82 pp. - Harry Aveling, Umar Junus, Perkembangan puisi Melayu moden. Dewan Bahasa dan Pustaka, Kuala Lumpur 1970. XIV + 161 pp. - A.F. Ros, Clifford Geertz, Islam observed: Religious development in Morocco and Indonesia. Yale University Press, New Haven and London 1968. XII en 136 blz. - Go Gien Tjwan, Joseph-John Nevadomsky, The Chinese in Southeast Asia. A selected and annotated bibliography of publications in Western languages 1960-1970. Occasional Paper No. 6 of the Center for South and Southeast Asia Studies, University of California, Berkeley, California, 1970, 119 p., Alice Li (eds. - F.G. Bailey, S. Arasaratnam, Indians in Malaysia and Singapore. Oxford University Press for Institute of Race Relations, London 1970. 241 pp. - A.F. Marks, G.J. Kruijer, Cuba; Voorbeeld en uitdaging. Polak en Van Gennep, Amsterdam, 1968. 146 bladzijden; met foto’s. - ,

  12. 分光光度法测定威灵仙中总皂苷的含量%Content of Saponin in Chinese Clematis Root Detected by Absorption Spectrometry

    Institute of Scientific and Technical Information of China (English)

    万德光; 裴瑾; 唐远; 范刚

    2007-01-01

    目的:测定威灵仙药材中总皂苷含量,建立威灵仙药材质量控制方法.方法:以三萜皂苷元齐墩果酸为对照,采用分光光度法.结果:齐墩果酸在0.0024,0.0480 mg/mL内线形关系良好(r=0.9998),平均回收率为95.51%,RSD=1.01%,测得威灵仙Clematis chinensis 中总皂苷含量为12.71%,东北铁线莲Clematis Terniflora var.mandshurica(Rupr)Ohwi.中总皂苷含量为9.21%,棉团铁线莲Clematis hexapetala Pall.中总皂苷含量为17.06%,其伪品菊科植物显脉旋复花Inula nervosa Wall.中总皂苷含量为4.95%,同属混淆品植物锥花铁线莲Clematis Panjculata Thunb.中总皂苷含量为2.24%.结论:本方法简便、准确、重现性好,可以将总皂苷含量做为威灵仙药材的质量控制指标,且表明正品威灵仙药材中总皂苷含量均比其伪品和混淆品的高.

  13. The Progress of Peoniflorin Therapy on Post-traumatic Stress Disorder%芍药苷治疗创伤后应激障碍的研究进展

    Institute of Scientific and Technical Information of China (English)

    何立雄; 杨凡; 梅强

    2011-01-01

    Post-traumatic stress disorder(PTSD ) is a common, recurrent chronic mental disorder which ocrurs in military who suffers from sudden events ,leading to a high frequency of suicide and funtional impairment. As there is much misunderstanding on PTSD, more difficulties are encountered in the treatment. Lately, there are many new discoveries in neurobiology, including peoniflorin monomer's distinguished effect on anti-depression, anti-anxiety and neural protection. It is verv likely that the symptoms will be completely relieved or mostly eliminated and the functional rehabilitation is in the horizon. Paeonia lactiflora pall has a wide application prospect in anti-PTSD field, and the exploration of the effective components and the development of a highly effective preparation with low side-effects and great clinical significance is expected.%创伤后应激障碍(PTSD)是军人应对突发事件后常见、反复发作的慢性精神障碍,有较高的自杀率与功能损害.由于人们对PTSD有很多误解,所以治疗存在较多困难.近年来,PTSD在神经生物学方面有了更多新发现,芍药苷单体成分具有显著的抗抑郁、抗焦虑和神经保护作用,临床症状完全缓解或大部分消除及功能康复是可期待的.芍药在抗PTSD方面有着广阔的应用前景,有希望将芍药及其有效成分开发成临床效果显著、低毒高效、药效持久的抗PTSD制剂.

  14. Effects of Inflorescence Stem Structure and Cell Wall Components on the Mechanical Strength of Inflorescence Stem in Herbaceous Peony

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    Qingping Geng

    2012-04-01

    Full Text Available Herbaceous peony (Paeonia lactiflora Pall. is a traditional famous flower, but its poor inflorescence stem quality seriously constrains the development of the cut flower. Mechanical strength is an important characteristic of stems, which not only affects plant lodging, but also plays an important role in stem bend or break. In this paper, the mechanical strength, morphological indices and microstructure of P. lactiflora development inflorescence stems were measured and observed. The results showed that the mechanical strength of inflorescence stems gradually increased, and that the diameter of inflorescence stem was a direct indicator in estimating mechanical strength. Simultaneously, with the development of inflorescence stem, the number of vascular bundles increased, the vascular bundle was arranged more densely, the sclerenchyma cell wall thickened, and the proportion of vascular bundle and pith also increased. On this basis, cellulose and lignin contents were determined, PlCesA3, PlCesA6 and PlCCoAOMT were isolated and their expression patterns were examined including PlPAL. The results showed that cellulose was not strictly correlated with the mechanical strength of inflorescence stem, and lignin had a significant impact on it. In addition, PlCesA3 and PlCesA6 were not key members in cellulose synthesis of P. lactiflora and their functions were also different, but PlPAL and PlCCoAOMT regulated the lignin synthesis of P. lactiflora. These data indicated that PlPAL and PlCCoAOMT could be applied to improve the mechanical strength of P. lactiflora inflorescence stem in genetic engineering.

  15. Rapid Propagation of Sweet and Sour Cherry Rootstocks

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    Dušica DORIĆ

    2014-12-01

    Full Text Available The paper presents a protocol for micropropagation of Prunus sp. rootstocks included in the sweet and sour cherry breeding program. Germplasm diversity for rootstock breeding derives from natural populations, where conditions and biological vectors for systematic infection with viral diseases are constantly present. The establishment of aseptic culture depends primarily on the explant type, as all selections were collected from natural habitat. For nearly all investigated selections, dormant buds were the favored source, due to enabling rosette initiation in more than 58% cases. In P. cerasus L. selections, 100% contamination was noted when shoot tips were used as an explant source. Significant influence of the double-phase medium on the number and height of multiplied shoots was observed in the standard cherry rootstock, ‘Gisela 6’. For P. fruticosa Pall., selection ‘SV1’ and ‘SV2’, and P. cerasus ‘D6’ selection, the double-phase medium also had a significant effect on the height of multiplied shoots, when compared to solid DKW (Driver and Kuniyuki Walnut medium. Genetic variability of selections within the investigated species resulted in variable plant rooting success. Adding Fe-EDDHA (Ethylenediamine di-2-hydroxy-phenyl acetate ferric in the 200 mg l-1 concentration to the rooting medium significantly enhanced the percentage of rooted plants. The highest rooting percentage was noted for ‘Gisela 6’ and ‘D6’ genotype at 1 mg l-1 IBA (indole-3-butyric acid, while 0.8 mg l-1 was the optimum concentration for P. mahaleb L. ‘M1’ selection. P. fruticosa genotypes required significantly higher IBA concentration for rooting (2.5 and 3.5 mg l-1.

  16. Sedimentary record of polycyclic aromatic hydrocarbons in Lake Erhai,Southwest China

    Institute of Scientific and Technical Information of China (English)

    Jianyang Guo; Zhang Liang; Haiqing Liao; Zhi Tang; Xiaoli Zhao; Fengchang Wu

    2011-01-01

    The temporal distribution of polycyclic aromatic hydrocarbons (PAHs) was investigated in a sediment core from Lake Erhal in Southwest China using gas-chromatography/mass spectrometry (GC/MS) method.The total organic carbon (TOC) normalized total PAHs concentrations (sum of US Environmental Protection Agency proposed 16 priority PAHs) ranged from 31.9 to 269 μg/g dry weight (dw),and were characterized by a slowly increasing stage in the deeper sediments and a sharp increasing stage in the upper sediments.The PAHs in the sediments were dominated by low molecular weight (LMW) PAHs,suggesting that the primary source of PAHs was low- and moderate temperature combustion processes.However,both the significant increase in high molecular weight (HMW) PAHs in the upper sediments and the vertical profile of diagnostic ratios pointed out a change in the sources of PAHs from low-temperature combustion to high-temperature combustion.The ecotoxicological assessment based on consensus-based sediment quality guidelines implied that potential adverse biological impacts were possible for benzo(ghi)perylenelene and most LMW PAHs.In addition,the total BaP equivalent quotient of seven carcinogenic polycyclic aromatic hydrocarbons (BaA,CHr,BbF,BkF,BaP,DBA and INP) was 106.1 ng/g,according to the toxic equivalency factors.Although there was no great biological impact associated with the HMW PAlls,great attention should be paid to these PAH components based on their rapid increase in the upper sediments.

  17. Trends in market share of leading cigarette brands in the USA: national survey on drug use and health 2002–2013

    Science.gov (United States)

    Sharma, Anushree; Fix, Brian V; Delnevo, Cristine; Cummings, K Michael; O'Connor, Richard J

    2016-01-01

    Objectives The main objective of this study is to examine trends in market share for leading cigarette brands, both before (2002–2008) and after (2009–2013) Food and Drug Administration (FDA) regulation of tobacco products. Design Data come from the annual National Survey on Drug Use and Health from 2002 through 2013. Descriptive statistics, cross tabulations, and logistic regression were employed. Data were weighted to the US population and adjusted for cigarette consumption. Our analysis is restricted to 164 343 current cigarette smokers who were at least 12 years of age or older, had smoked at least one cigarette in the 30 days prior to the survey, and reported a usual cigarette brand at the time of the survey. Results Over 12 years, 14 brands comprised over 77% of the cigarette market. Marlboro consistently held over 38% of the market. Newport held the second highest market share, and increased from 7.2% in 2002 to 10.9% by 2013. Market share of Pall Mall grew by over 400% (1.7% in 2002 vs 8.9% in 2013), likely aided by the 2009 Federal excise tax increase. No clear associations of changes in market share with the implementation of FDA's regulatory authority over tobacco in 2009 were noted. Conclusions Tracking market share trends offers clues about brand marketing changing preferences of consumers. Rapidly growing cigarette brands should be monitored to determine if specific marketing practices or design changes are drivers, as these could represent public health concerns. Monitoring trends in cigarette market share could inform regulatory decision-making efforts related to marketing and advertising. PMID:26826144

  18. Estimation of thyroid gland state of voles natural populations from increased radioactive background territories

    Energy Technology Data Exchange (ETDEWEB)

    Raskosha, O.; Ermakova, O.; Kaneva, A. [Institute of Biology of Komi Scientific Center, Ural Division of Russian Academy of Science (Russian Federation)

    2014-07-01

    Investigation of effects caused in biological objects by chronic low-intensity radiation in their natural habitats is one of the most important problems of modern radioecology. The aim of our work - complex estimation of state of thyroid gland of voles inhabiting increased radioactive background territories. We investigated tundra voles (Microtus oeconomus Pall.) that were sampled at different stages of population cycle from the experimental and the control sites in the Uhta region of the Komi Republic, Russia. Experimental site contamination resulted from commercial extraction od radium between the 1930's and 1950's. Irradiation exposure dose at the site was 50-2000 mR/h (at the control site 10-15 mR/h). Complex estimation of thyroid was made by histological, morpho-metrical, radioimmunological and cytogenetic methods. Results showed high sensitivity of thyroid gland of tundra voles from chronically irradiated natural populations. We found reliable changes in morphological features of thyroid, in the level of thyroidal hormones and increased frequency of cells with micro-nucleuses in animals sampled from the experimental site as compared with the control ones. It was also showed, that chronic exposure of ionizing irradiation at the same range of absorbed doses can cause different effects in animals depending on sex, age and the stage of population cycle. This confirms the need of including these biological factors to analysis of low doses effects in the natural populations during radioecological studies. Investigations were supported by RFBR grants No. 13-04-01750? and No. 13-04-90351-RBUa. Document available in abstract form only. (authors)

  19. On Chaotic Nature of the Emerging European Forex Markets

    Directory of Open Access Journals (Sweden)

    Anoop S Kumar

    2014-06-01

    Full Text Available This study attempts to analyze the presence deterministic chaos in the forex markets of select European countries namely Bulgaria, Croatia, Czech Republic, Hungary Poland, Romania, Russia, Slovakia and Slovenia. Monthly NEER data ranging from jan-1994 to Dec-2013 is used for the purpose of analysis. A two step methodology is employed where in the first step, non-linear dependence structure in the underlying time series is verified using BDS test. The results show that all the markets under study exhibit non-linear dependence. In the next stage, it is enquired whether this non-linear behavior is due to the presence of chaotic dynamics in the markets. This is achieved by estimating Lyapunov exponents for the time series under analysis. An EGARCH (1, 1 filter is applied to see if the non-linearity could be explained by a GARCH process. From the Lyapunov exponent values, it is found that the GARCH process is unable to explain the forex markets behavior in a satisfying manner. It is concluded that the forex markets under study exhibit deterministic chaotic behavior.

  20. Molecular dynamics of amorphous pharmaceutical fenofibrate studied by broadband dielectric spectroscopy$

    Institute of Scientific and Technical Information of China (English)

    U. Sailaja; M. Shahin Thayyil; N.S. Krishna Kumar; G. Govindaraj

    2016-01-01

    Fenofibrate is mainly used to reduce cholesterol level in patients at risk of cardiovascular disease. Thermal transition study with the help of differential scanning calorimetry (DSC) shows that the aforesaid active pharmaceutical ingredient (API) is a good glass former. Based on our DSC study, the molecular dynamics of this API has been carried out by broadband dielectric spectroscopy (BDS) covering wide temperature and frequency ranges. Dielectric measurements of amorphous fenofibrate were per-formed after its vitrification by fast cooling from a few degrees above the melting point (Tm ¼ 354.11 K) to deep glassy state. The sample does not show any crystallization tendency during cooling and reaches the glassy state. The temperature dependence of the structural relaxation has been fitted by single Vogel–Fulcher–Tamman (VFT) equation. From VFT fit, glass transition temperature (Tg) was estimated as 250.56 K and fragility (m) was determined as 94.02. This drug is classified as a fragile glass former. Deviations of experimental data from Kohlrausch–Williams–Watts (KWW) fits on high-frequency flank of α-peak indicate the presence of an excess wing in fenofibrate. Based on Ngai's coupling model, we identified the excess wing as true Johari–Goldstein (JG) process. Below the glass transition temperature one can clearly see a secondary relaxation (γ) with an activation energy of 32.67 kJ/mol.

  1. DOES INCREASING DENTAL EDUCATION IMPROVE THE ORAL HYGIENE STATUS OF DENTAL STUDENTS?

    Directory of Open Access Journals (Sweden)

    Purnima V.

    2015-06-01

    Full Text Available OBJECTIVES: The purpose of this study was to assess the impact of increased knowledge acquired by the dental student in preventive aspects of dental education during his curriculum on his own health attitude, oral hygiene and gingival status. METHODS: A total of 240 students pursuing the undergraduate course (B.D.S at t he New Horizon Dental College and Research Institute, Bilaspur (Chhattisgarh were recruited for the study and divided into 4 groups based on the year of study. All participants answered a self - administered questionnaire and then this reported oral health behavior was compared to the actual clinical situation using the clinical parameters of Plaque Index, Gingival Index and Oral Hygiene Index simplified. RESULTS: The dental attitude became more positive and improved with each advancing year of education. Th ere was a statistically significant decrease in the CPI score (P=0.04 and OHI - S score (P=0.01 with each advancing year of education but plaque score was insignificant (P=0.06. Females showed better dental care than their male counterparts. CONCLUSION: T he oral health attitude and behavior of the dental students improved with increasing level of dental education. Preventive courses providing apt information on proper techniques of plaque control must be included in the first and second year curriculum of the dental students.

  2. Temperature constraints on the coldest brown dwarf known WISE 0855-0714

    CERN Document Server

    Beamín, J C; Bayo, A; Mužić, K; Boffin, H M J; Allard, F; Homeier, D; Minniti, D; Gromadzki, M; Kurtev, R; Lodieu, N; Martin, E L; Mendez, R A

    2014-01-01

    Context. Nearby isolated planetary mass objects are beginning to be discovered, but their individual properties are poorly constrained because their low surface temperatures and strong molecular self-absorption make them extremely faint. Aims. We aimed to detect the near infrared emission of the coldest brown dwarf (BD) found so far WISE0855$-$0714, located $\\sim$2.2 pc away, and to improve its temperature estimate (T$_{\\rm eff}$= 225-260 K) from a comparison with state of the art models of BD atmospheres. Methods. We observed the field containing WISE0855-0714 with HAWK-I at the VLT in the $Y$ band. For BDs with T$_{\\rm eff}24.4 mag at 3-$\\sigma$ level, leading to Y-[4.5]>10.5. Combining this limit with previous detections and upper limits at other wavelengths, WISE0855-0714 is confirmed as the reddest BD detected. We applied spectral energy distribution fitting with collections of models from two independent groups for extremely cool BD atmospheres leading to an effective temperature of T$_{\\rm eff}<$250...

  3. Study on high temperature design methodology of heat-resistant materials for GEN-IV systems

    Energy Technology Data Exchange (ETDEWEB)

    Ryu, Woo Seog; Kim, D. W.; Kim, S. H.; Kim, W. G.; Kim, J. H.; Park, D. G.; Yoon, J. H.; Lee, H. Y.; Hing, J. H

    2005-08-15

    Analysis of the existing high temperature design and assessment codes such as US(ASME-NH,Draft Code Case for Alloy 617), France(RCC-MR), UK(R5), Japan(BDS/DDS/FDS) for Gen IV reactor structure has been carried out. In addition the scope and fields for research and development is needed in the future have been defined. For assessing the high temperature creep cracks, time dependent fracture mechanics (TDFM) parameters of the C and Ct were analyzed. The creep propagation data were obtained from the creep crack growth tests for type 316LN stainless steels, and creep crack growth testing machine for Gen-IV system up to 950 .deg. C was set up. Damage mechanism and causes for creep-fatigue were investigated. The difference between prediction creep-fatigue life and experimental life were investigated. Material properties for analysis creep-fatigue damage were recommended. The assessment procedure (Draft) on creep-fatigue crack initiation has been developed based on the technical appendix A16 of French RCC-MR code. Ultrasonic wave signal against creep ruptured specimens of type 316LN stainless steel was obtained. It was identified that creep damage can be evaluated by ultrasonic method. The NDT techniques evaluated include Barkhausen noise, magnetic hysteresis parameters, positron annihilation, X-ray diffraction and small angle neutron scattering. Experimental procedure and evaluation method of material integrity were developed through the fracture toughness test of Cr-Mo steel.

  4. Neutron production in deuterium gas-puff z-pinch with outer plasma shell at current of 3 MA

    Science.gov (United States)

    Cikhardt, J.; Klir, D.; Rezac, K.; Cikhardtova, B.; Kravarik, J.; Kubes, P.; Sila, O.; Shishlov, A. V.; Cherdizov, R. K.; Frusov, F. I.; Kokshenev, V. A.; Kurmaev, N. E.; Labetsky, A. Yu.; Ratakhin, N. A.; Dudkin, G. N.; Garapatsky, A. A.; Padalko, V. N.; Varlachev, V. A.; Turek, K.; Krasa, J.

    2015-11-01

    Z-pinch experiments at the current of about 3 MA were carried out on the GIT-12 generator. The outer plasma shell of deuterium gas-puff was generated by the system of 48 plasma guns. This configuration exhibits a high efficiency of the production of DD fusion neutrons with the yield of above 1012 neutrons produced in a single shot with the duration of about 20 ns. The maximum energy of the neutrons produced in this pulse exceeded 30 MeV. The neutron radiation was measured using scintillation TOF detectors, CR-39 nuclear track detectors, bubble detectors BD-PND and BDS-10000 and by several types of nuclear activation detectors. These diagnostic tools were used to measure the anisotropy of neutron fluence and neutron energy spectra. It allows us to estimate the total number of DD neutrons, the contribution of other nuclear reactions, the amount of scattered neutrons, and other parameters of neutron production. This work was supported by the MSMT grants LH13283, LD14089.

  5. Long-Implosion-Time Z-pinch Experiments with Deuterium Gas-Puffs on the GIT-12 Generator

    Science.gov (United States)

    Klir, D.; Kubes, P.; Rezac, K.; Cikhardt, J.; Kravarik, J.; Shishlov, A.; Labetsky, A.; Fursov, F.; Kokshenev, V.; Kovalchuk, B.; Kurmaev, N.; Ratakhin, N.

    2012-10-01

    Experiments with deuterium triple shell gas-puffs have been carried out on the GIT-12 generator at the IHCE in Tomsk. Outer, middle, and inner nozzle diameters were 160 mm, 80 mm and 30 mm, respectively. The influence of the mass of deuterium shells on neutron emission times, neutron yields and neutron spectra was studied. The linear mass density of deuterium varied between 50 and 270 μg/cm. Gas puffs imploded onto the axis before the peak of a generator current at 700-1100 ns. The first neutron peak occurred during the stagnation. Most of the neutrons were emitted during the second neutron pulse after the development of instabilities. In lower mass gas puffs, neutron energies of up to 4.4 MeV gave the evidence of 1 MeV deuterons. The peak neutron yield from D(d,n)^3He reactions reached 3x10^11 on a current level of 2.5 MA. Secondary DT neutrons were measured by BDS-10000 bubble detectors. An average neutron yield ratio Y>10 MeV/Y2.5 MeV exceeded (6±3)x10-4. Ne-Ne-D2 and Ne-D2-D2 gas puffs produced 3 times lower neutron yields but the first neutron pulse during the stagnation was nearly the same as with D2-D2-D2 gas puffs.

  6. HPLC法测定地锦草灌肠液中苦参碱的含量%Determination of grass enema Verbena matrine in by HPLC

    Institute of Scientific and Technical Information of China (English)

    佘永红; 李璞; 周顺

    2010-01-01

    目的:建立地锦草灌肠液中苦参碱的含量测定.方法:采用HPLC法,色谱柱为BDS Hypersil C18柱,流动相为甲醇-乙腈-三乙胺-磷酸盐缓冲液,流速为1.0 mL·min-1,检测波长为220 nm,柱温为室温,进样量为20 μL.结果:苦参碱在0.3616-4.338 μg范围内呈良好的线形关系(r=0.9996),平均回收率为97.7%,RSD%为0.77%(n=6).结论:该方法简便,准确,重现性好,可用于地锦草灌肠液的质量控制.

  7. HPLC Determination of Fexofenadine in Human Plasma For Therapeutic Drug Monitoring and Pharmacokinetic Studies.

    Science.gov (United States)

    Helmy, S A; El Bedaiwy, H M

    2016-07-01

    A simple and sensitive method was developed for fexofenadine determination in human plasma by liquid chromatography with ultraviolet detection. Satisfactory separation was achieved on a Hypersil® BDS C18 column (250 × 4.6 mm, 5μm) using a mobile phase comprising 20 mm sodium dihydrogen phosphate-2 hydrate (pH adjusted to 3 with phosphoric acid)-acetonitrile at a ratio of 52:48, v/v. The elution was isocratic at ambient temperature with a flow rate of 1.0 mL/min. The UV detector was set at 215 nm for the drug and 330 nm for the internal standared (tinidazole). The total time for a chromatographic separation was ~6.5 min. Linearity was demonstrated over the concentration range 0.01-4 μg/mL. The observed within- and between-day assay precision ranged from 0.346 to 13.6%; accuracy varied between 100.4 and 111.2%. This method was successfully applied for therapeutic drug monitoring in patients treated with clinical doses of fexofenadine and for pharmacokinetic studies. Copyright © 2015 John Wiley & Sons, Ltd. PMID:26577375

  8. Development and Validation of an HPLC Method for Simultaneous Quantification of Clopidogrel Bisulfate, Its Carboxylic Acid Metabolite, and Atorvastatin in Human Plasma: Application to a Pharmacokinetic Study

    Directory of Open Access Journals (Sweden)

    Octavian Croitoru

    2015-01-01

    Full Text Available A simple, sensitive, and specific reversed phase liquid chromatographic method was developed and validated for simultaneous quantification of clopidogrel, its carboxylic acid metabolite, and atorvastatin in human serum. Plasma samples were deproteinized with acetonitrile and ibuprofen was chosen as internal standard. Chromatographic separation was performed on an BDS Hypersil C18 column (250 × 4.6 mm; 5 μm via gradient elution with mobile phase consisting of 10 mM phosphoric acid (sodium buffer solution (pH = 2.6 adjusted with 85% orthophosphoric acid : acetonitrile : methanol with flow rate of 1 mL·min−1. Detection was achieved with PDA detector at 220 nm. The method was validated in terms of linearity, sensitivity, precision, accuracy, limit of quantification, and stability tests. Calibration curves of the analytes were found to be linear in the range of 0.008–2 μg·mL−1 for clopidogrel, 0.01–4 μg·mL−1 for its carboxylic acid metabolite, and 0.005–2.5 μg·mL−1 for atorvastatin. The results of accuracy (as recovery with ibuprofen as internal standard were in the range of 96–98% for clopidogrel, 94–98% for its carboxylic acid metabolite, and 90–99% for atorvastatin, respectively.

  9. Non-leptonic decays of $B \\to ( f_1(1285),f_1(1420) ) V$ in the perturbative QCD approach

    CERN Document Server

    Liu, Xin; Zou, Zhi-Tian

    2016-01-01

    We investigate the branching ratios, the polarization fractions, the direct CP-violating asymmetries, and the relative phases in 20 non-leptonic decay modes of $B \\to f_1 V$ within the framework of perturbative QCD approach at leading order with $f_1$ including two $^3\\!P_1$-axial-vector states $f_1(1285)$ and $f_1(1420)$. Here, $B$ denotes $B^+$, $B^0$, and $B_s^0$ mesons and $V$ stands for the lightest vector mesons $\\rho$, $K^*$, $\\omega$, and $\\phi$ , respectively. The $B_s^0 \\to f_1 V$ decays are studied theoretically for the first time in the literature. Together with the angle $\\phi_{f_1} \\approx (24^{+3.2}_{-2.7})^\\circ$ extracted from the measurement through $B_{d/s} \\to J/\\psi f_1(1285)$ modes for the $f_1(1285)-f_1(1420)$ mixing system, it is of great interest to find phenomenologically that some modes such as the tree-dominated $B^+ \\to f_1 \\rho^+$ and the penguin-dominated $B^{+,0} \\to f_1 K^{*+,0}, B_s^0 \\to f_1 \\phi$ with large branching ratios around ${\\cal O}(10^{-6})$ or even ${\\cal O}(10^{-...

  10. Content determination of benzyl glucosinolate and anti-cancer activity of its hydrolysis product inCarica papaya L.

    Institute of Scientific and Technical Information of China (English)

    Ze-You Li; Yong Wang; Wen-Tao Shen; Peng Zhou

    2012-01-01

    Objective:To determine the content of benzyl glucosinolate(BG)in the pulp and the seed and investigate the anti-cancer activity of its hydrolysis product inCarica papaya L.Methods:Determination ofBG was performed on an HypersilBDS C18 column at the wavelength of214 nm with0.1% trifluoroacetic acid (TFA)aqueous solution (A) and 0.1%TFA acetonitrile (B)as the mobile phase. In vitro activity test was adopted with cultured human lung cancerH69 cellin vitro to investigate the inhibition rate of cell proliferation of benzyl isothiocyanate(BITC)againstH69 cell.Results: The pulp has more BG before the maturation of papaya and it nearly disappeared after papaya matured, while the seed containsBG at every stage. Activity test demonstrated that the a higher concentration ofBITC would have better inhibition rate of cell proliferation onH69 cell, and the IC50 was6.5 μmol/L.Conclusions:BG also can be produced in the pulp of papaya and it will be stored in the seed after the fruit has been matured. The hydrolysis product ofBG has certain cancer-prevention anti-cancer activities for human.

  11. Molecular dynamics of amorphous pharmaceutical fenofibrate studied by broadband dielectric spectroscopy

    Directory of Open Access Journals (Sweden)

    U. Sailaja

    2016-06-01

    Full Text Available Fenofibrate is mainly used to reduce cholesterol level in patients at risk of cardiovascular disease. Thermal transition study with the help of differential scanning calorimetry (DSC shows that the aforesaid active pharmaceutical ingredient (API is a good glass former. Based on our DSC study, the molecular dynamics of this API has been carried out by broadband dielectric spectroscopy (BDS covering wide temperature and frequency ranges. Dielectric measurements of amorphous fenofibrate were performed after its vitrification by fast cooling from a few degrees above the melting point (Tm=354.11 K to deep glassy state. The sample does not show any crystallization tendency during cooling and reaches the glassy state. The temperature dependence of the structural relaxation has been fitted by single Vogel–Fulcher–Tamman (VFT equation. From VFT fit, glass transition temperature (Tg was estimated as 250.56 K and fragility (m was determined as 94.02. This drug is classified as a fragile glass former. Deviations of experimental data from Kohlrausch–Williams–Watts (KWW fits on high-frequency flank of α-peak indicate the presence of an excess wing in fenofibrate. Based on Ngai׳s coupling model, we identified the excess wing as true Johari–Goldstein (JG process. Below the glass transition temperature one can clearly see a secondary relaxation (γ with an activation energy of 32.67 kJ/mol.

  12. Validated Stability-indicating High-performance Liquid Chromatographic Method for Estimation of Degradation Behaviour of Eberconazole Nitrate and Mometasone Furoate in Cream Formulation

    Directory of Open Access Journals (Sweden)

    N Sharma

    2013-01-01

    Full Text Available The objective of current investigation was to study the degradation behaviour of eberconazole nitrate and mometasone furoate under different International Conference on harmonisation recommended stress condition using reverse phase high performance liquid chromatographic method and to establish validated stability-indicating high performance liquid chromatographic method to determine purity of eberconazole nitrate and mometasone furoate in presence of its impurities, forced degradation products and placebo in pharmaceutical dosage forms. The method was developed using Hypersil BDS, C18, 150Χ4.6 mm, 5 μ as stationary phase with mobile phase containing a gradient mixture of solvent A and B. 0.01 M phosphate buffer with 0.1% triethyl amine, adjusted pH 7.0 with phosphoric acid was used as buffer. Buffer pH 7.0 was used as solvent A and methanol:acetonitrile in 150:850 v/v ratios were used as solvent B. The eluted compounds were monitored at 240 nm. The run time was 50 min. The developed method was validated as per international conference on harmonization guidelines with respect to specificity, linearity, limit of detection, limit of quantification, accuracy, precision and robustness.

  13. The bimodal initial mass function in the Orion Nebula Cloud

    CERN Document Server

    Drass, H; Chini, R; Bayo, A; Hackstein, M; Hoffmeister, V; Godoy, N; Vogt, N

    2016-01-01

    Due to its youth, proximity and richness the Orion Nebula Cloud (ONC) is an ideal testbed to obtain a comprehensive view on the Initial Mass Function (IMF) down to the planetary mass regime. Using the HAWK-I camera at the VLT, we have obtained an unprecedented deep and wide near-infrared JHK mosaic of the ONC (90% completeness at K~19.0mag, 22'x28). Applying the most recent isochrones and accounting for the contamination of background stars and galaxies, we find that ONC's IMF is bimodal with distinct peaks at about 0.25 and 0.025 M_sun separated by a pronounced dip at the hydrogen burning limit (0.08 M_sun), with a depth of about a factor 2-3 below the log-normal distribution. Apart from ~920 low-mass stars (M 0.005 M_sun, hence about ten times more substellar candidates than known before. The substellar IMF peak at 0.025 M_sun could be caused by BDs and IPMOs which have been ejected from multiple systems during the early star-formation process or from circumstellar disks.

  14. Validation of extraction, clean-up and DR CALUX {sup registered} bioanalysis. Pt. I. Feedingstuff

    Energy Technology Data Exchange (ETDEWEB)

    Besselink, H.; Jonas, A.; Brouwer, B. [BioDetection Systems BV (BDS), Amsterdam (Netherlands); Pijnappels, M.; Swinkels, A. [Masterlab BV, Boxmeer (Netherlands)

    2004-09-15

    Feed safety is a high priority issue for the feed sector as it directly impacts at the beginning of the food-chain. Currently stringent EU limit values are in force for dioxins in feedingstuffs for animal and public health protection. Biodetection Systems BV's (BDS) DR CALUX {sup registered} bioassay is a cost-effective and rapid method to measure low levels of dioxins and dioxin-like compounds in various matrices. The use of bioassays for monitoring dioxins in feed allows the (pre)-selection of samples suspected of being contaminated above limit values with dioxins. To permit bioassays to be used for screening feedingstuffs for the presence of dioxins and related compounds, the EU has laid down general requirements for the determination of dioxins and dioxin-like PCBs in feedingstuffs and specific requirements for cell-based bioassays. To ensure reliability the DR CALUX {sup registered} bioassay, validated methods for extraction and DR CALUX {sup registered} analysis are necessary. Within the framework of the development of DR CALUX {sup registered} analysis methods, extraction and clean-up methods for 13 feedingstuffs were evaluated, selected and validated. In this paper we present the results of this substantive multi-matrix feedingstuffs validation study.

  15. Substellar Objects in Nearby Young Clusters VII: The substellar mass function revisited

    CERN Document Server

    Scholz, Aleks; Clark, Paul; Jayawardhana, Ray; Muzic, Koraljka

    2013-01-01

    The abundance of brown dwarfs (BDs) in young clusters is a diagnostic of star formation theory. Here we revisit the issue of determining the substellar initial mass function (IMF), based on a comparison between NGC1333 and IC348, two clusters in the Perseus star-forming region. We derive their mass distributions for a range of model isochrones, varying distances, extinction laws and ages, with comprehensive assessments of the uncertainties. We find that the choice of isochrone and other parameters have significant effects on the results, thus we caution against comparing IMFs obtained using different approaches. For NGC1333, we find that the star/BD ratio R is between 1.9 and 2.4, for all plausible scenarios, consistent with our previous work. For IC348, R is between 2.9 and 4.0, suggesting that previous studies have overestimated this value. Thus, the star forming process generates about 2.5-5 substellar objects per 10 stars. The derived star/BD ratios correspond to a slope of the power-law mass function of ...

  16. Research RP - HPLC determination of glaucocalyxin A in rat plasma and its pharmacokinetic and excretion%RP-HPLC法测定大鼠血浆中蓝萼甲素含量与药代动力学及排泄研究

    Institute of Scientific and Technical Information of China (English)

    曹露晔; 陈子君; 李云森; 李仪奎; 马越鸣; 金若敏

    2006-01-01

    目的:研究蓝萼甲素在大鼠体内的药代动力学过程及排泄过程并建立大鼠生物样品测定的高效液相色谱方法.方法:采用液液萃取的方法从生物样品中提取出蓝萼甲素后用Hypersil BDS C18(250 mm×4.6 mm,5μm)柱进行分离,流动相为甲醇-水(45∶55).结果:蓝萼甲素在大鼠体内静脉给药后药代动力学符合二房室模型.t1/2α和t1/2β分别为4.32 min和28.56min,12 h蓝萼甲素在尿、粪便中的排泄量分别为12.8%和23.8%,在10 h内胆汁中的排泄量为35.68%.结论:此方法快捷、灵敏、简便,适合于蓝萼甲素的药代动力学研究.

  17. Correlations in Minimal U(2)^3 models and an SO(10) SUSY GUT model facing new data

    CERN Document Server

    Girrbach, Jennifer

    2012-01-01

    Models with an approximate U(2)^3 flavour symmetry represent simple non-MFV extensions of the SM. We compare correlations of Delta F = 2 observables in CMFV and in a minimal version of U(2)^3 models, MU(2)^3, where only the minimal set of spurions for breaking the symmetry is used and where only SM operators are relevant. Due to the different treatment of the third generation MU(2)^3 models avoid the Delta M_{s,d}-|epsilon_K| correlation of CMFV which precludes to solve the S_{psi K_S}- |epsilon_K| tension present in the flavour data. While the flavour structure in K meson system is the same for CMFV and MU(2)^3 models, CP violation in B_{d,s} system can deviate in MU(2)^3 models from CMFV. We point out a triple correlation between S_{psi phi}, S_{psi K_S} and |V_{ub}| that can provide a distinction between different MU(2)^3 models. GUTs open the possibility to transfer the neutrino mixing matrix U_{PMNS} to the quark sector which leads to correlations between leptonic and hadronic observables. This is accomp...

  18. Development and Validation of New RP-HPLC Method for Simultaneous Determination of Methyl and Propyl Parabens with Levetiracetam in Pure Form and Pharmaceutical Formulation

    Directory of Open Access Journals (Sweden)

    Soad S. Abd El-Hay

    2016-01-01

    Full Text Available A simple and robust high-performance liquid chromatography (HPLC method is described for the assay for levetiracetam (LTC, methyl paraben (MHB, and propyl paraben (PHB either in their pure form or in commercial Levepsy® syrup. The method is selective and stability indicating and all chromatographic conditions were studied to obtain adequate separation of LTC, MHB, and PHB from their degradation products and from excipients. The HPLC separation was carried out on a RP C18 Hypersil BDS analytical column (150 mm × 4.6 mm ID using gradient elution system. The mobile phase flow rate was 1.5 mLmin−1 and the column temperature was kept at 40°C. Complete separation of the studied components was obtained within a cycle time of 8 min. LTC, MHB, and PHB were eluted at 1.56, 5.86, and 7.85 min, respectively. Detection was carried out at 240 nm using a dual wavelength detector. The method has been validated for linearity, accuracy, precision, specificity, limit of detection, limit of quantitation, robustness, and ruggedness. The proposed method was successfully applied for the determination of LTC in the presence of parabens in Levepsy syrup.

  19. Application of solid-phase extraction for determination of phenolic compounds in barrique wines.

    Science.gov (United States)

    Matejícek, D; Klejdus, B; Mikes, O; Sterbová, D; Kubán, V

    2003-09-01

    A fast, selective and sensitive chromatographic method has been developed for determination of gallic, protocatechuic, p-hydroxybenzoic, vanillic, caffeic, syringic, p-coumaric, benzoic, ferulic, sinapic, cinnamic, and ellagic acids and p-hydroxybenzaldehyde, vanillin, syringaldehyde, 2-furfural, 5-methylfurfural, and 5-methoxyfurfural. The compounds from untreated wine samples were pre-concentrated and cleaned using solid-phase extraction on RP-105 polymeric sorbent. The cartridge was conditioned with methanol and water. Co-extracted ballast substances were rinsed from the sorbent with 0.1 mol L(-1) hydrochloric acid-methanol, 1:4 (v/ v). Retained phenolic compounds were selectively eluted with diethyl ether. A linear mobile phase gradient containing 0.3% acetic acid and methanol was used for final baseline chromatographic separation on a Hypersil BDS C18 column. Limits of detection (LOD=3 s(bl)) in the range 5.2 to 181.2 microg L(-1), resolution (R) better than 1.7, and repeatability of 2.7-5.1% (RSD for real samples) were achieved. The method was applied for quantification of individual phenolic compounds in barrique wines. PMID:12923605

  20. Development and Validation of a Stability-Indicating Assay of Etofenamate by RP-HPLC and Characterization of Degradation Products.

    Science.gov (United States)

    Peraman, Ramalingam; Nayakanti, Devanna; Dugga, Hari Hara Theja; Kodikonda, Sudhakara

    2013-12-01

    A validated stability-indicating RP-HPLC method for etofenamate (ETF) was developed by separating its degradation products on a C18 (250 mm × 4.6 mm 5 μm) Qualisil BDS column using a phosphate buffer (pH-adjusted to 6.0 with orthophosphoric acid) and methanol in the ratio of 20:80 % v/v as the mobile phase at a flow rate of 1.0 mL/min. The column effluents were monitored by a photodiode array detector set at 286 nm. The method was validated in terms of specificity, linearity, accuracy, precision, detection limit, quantification limit, and robustness. Forced degradation of etofenamate was carried out under acidic, basic, thermal, photo, and peroxide conditions and the major degradation products of acidic and basic degradation were isolated and characterized by (1)H-NMR, (13)C-NMR, and mass spectral studies. The mass balance of the method varied between 92-99%. PMID:24482770