Sample records for biotechnology operations support

  1. Cellular Biotechnology Operations Support Systems-Fluid Dynamics Investigation (CBOSS-FDI) (United States)


    Aboard the International Space Station (ISS), the Tissue Culture Module (TCM) is the stationary bioreactor vessel in which cell cultures grow. However, for the Cellular Biotechnology Operations Support Systems-Fluid Dynamics Investigation (CBOSS-FDI), color polystyrene beads are used to measure the effectiveness of various mixing procedures. Uniform mixing is a crucial component of CBOSS experiments involving the immune response of human lymphoid cell suspensions. In this picture, the beads are trapped in the injection port shortly after injection. Swirls of beads indicate, event to the naked eye, the contents of the TCM are not fully mixed. The beads are similar in size and density to human lymphoid cells. The goal is to develop procedures that are both convenient for the flight crew and are optimal in providing uniform and reproducible mixing of all components, including cells. The average bead density in a well mixed TCM will be uniform, with no bubbles, and it will be measured using the absorption of light

  2. Forest biotechnology advances to support global bioeconomy

    Directory of Open Access Journals (Sweden)

    Antoine Harfouche


    Full Text Available The world is shifting to an innovation economy and forest biotechnology can play a major role in the bio-economy by providing farmers, producers, and consumers with tools that can better advance this transition. First-generation or conventional biofuels are primarily produced from food crops and are therefore limited in their ability to meet challenges for petroleum-product substitution and climate change mitigation, and to overcome the food-versus-fuel dilemma. In the longer term, forest lignocellulosic biomass will provide a unique renewable resource for large-scale production of bioenergy, biofuels and bio-products. These second-generation or advanced biofuels and bio-products have also the potential to avoid many of the issues facing the first-generation biofuels, particularly the competition concerning land and water used for food production. To expand the range of natural biological resources the rapidly evolving tools of biotechnology can ameliorate the conversion process, lower the conversion costs and also enhance target yield of forest biomass feedstock and the product of interest. Therefore, linking forest biotechnology with industrial biotechnology presents a promising approach to convert woody lignocellulosic biomass into biofuels and bio-products. Major advances and applications of forest biotechnology that are being achieved to competitively position forest biomass feedstocks with corn and other food crops are outlined. Finally, recommendations for future work are discussed.

  3. Supporting Biotechnology Regulatory Policy Processes in Southeast ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Biotechnology innovations or bio-innovations can provide solutions to problems associated with food security, poverty and environmental degradation. Innovations such as genetically engineered (GE) crops can increase food production and minimize (or totally obviate) the need for chemical fertilizers and pesticides.

  4. Forest biotechnology advances to support global bioeconomy


    Antoine Harfouche; Sacha Khoury; Francesco Fabbrini; Giuseppe Scarascia Mugnozza


    The world is shifting to an innovation economy and forest biotechnology can play a major role in the bio-economy by providing farmers, producers, and consumers with tools that can better advance this transition. First-generation or conventional biofuels are primarily produced from food crops and are therefore limited in their ability to meet challenges for petroleum-product substitution and climate change mitigation, and to overcome the food-versus-fuel dilemma. In the longer term, forest lig...

  5. Biotechnology

    International Nuclear Information System (INIS)

    Lewanika, Mbikusita Mwananyanda


    The article sets out to explain in simple terms the main concepts of Biotechnology beginning with traditional biotechnology to modern biotechnology. It outlines fundamentals of Recombinant Deoxyribonucleic Acid (DNA), Genetically Modified Organisms (GMOs) and Genetic Engineering. The article offers a discussion of the benefits, disadvantages and the general public and policy concerns regarding genetically modified organisms

  6. Non clinical research at CENTIS supporting biotechnological and pharmaceutical industry

    International Nuclear Information System (INIS)

    Hernandez Gonzalez, Ignacio


    Drugs production is a highly demanding industry because the rigor of legislations and guidelines. Standards are applied to manufacturing facilities and also to research and development stage. Our national biotechnological industry is developing and producing important medications for diseases like cancer, some of them in the national and international market. Isotopes Centre is an institution supporting such development by means of a work platform to carry out researches in the field of pharmacokinetic and biodistribution in experimental models. Accumulated experience allows us to contribute to research and development of different kind of molecules as pharmaceuticals, specially the biotechnological ones. We are evolving in direction to new technologies and methodologies more suitable to current standards. Radiolabeling is still a convenient choice considering present and new imaging technologies to investigate distribution and kinetic in living subjects. With the techniques we have and the ones to incorporate in a near future, new and more demanding investigations will be affordable. (author)

  7. Biotechnology

    Energy Technology Data Exchange (ETDEWEB)



    The guidelines of the Biotechnology Program are research and development aiming to develop and manufacture products of pharmaceutical interest. This Program has two main research areas, namely Pituitary Hormones and Biopharmaceuticals. The first one comprises a group with a long experience on Recombinant Human Pituitary Hormone synthesis, purification and characterization. The Biopharmaceutical area is dedicated to the research of isolation, structural analysis and biological activities in different biological system of macromolecules. The Animal Laboratory Division of IPEN is responsible for the breeding and production of small laboratory animal.

  8. Biotechnology

    Energy Technology Data Exchange (ETDEWEB)



    The guidelines of the Biotechnology Program are research and development aiming at developing and manufacturing products of pharmaceutical interest. This Program has two main research areas, namely Pituitary Hormones and Biopharmaceuticals. The first one comprises a group with a long experience on Recombinant Human Pituitary Hormone synthesis, purification and characterization. Up to now they have worked mostly with human growth hormone (hGH), human prolactin (hPRL), human thyrotropin (hTSH), human follicle stimulating hormone (hFSH) and human luteotropin (hLH), with a particular emphasis on glycoprotein carbohydrate structures. An important research line is devoted to Growth Hormone Gene Therapy, working mostly on animal models: immunocompetent and immunodeficient-dwarf mice. For several years this development has been based on ex vivo grafting of transduced keratinocytes, while more recently very promising results have been obtained with the injections and electroporation of naked plasmid DNA. Besides research, they have also activities in the Biotechnological Production and Downstream Processing of the same recombinant hormones, which are produced in both E. coli and mammalian cells and in the development of joint-ventures with the National Industry. The biological effects of radiation on cells are also studied, specially concerning the administration of {sup 131}I together with thyroid-stimulating hormone in thyroid cancer. The Biopharmaceutical area is dedicated to the research of isolation, structural analysis and biological activities in different biological systems of macromolecules. These macromolecules are peptides or proteins, either native or recombinant with medical or pharmaceutical interest. During this period new proteins related to serine protease activity, breast cancer development and angiogenesis were described. The effects of ionizing radiation on macromolecules have also been investigated to detoxify animal venoms in order to improve antigens

  9. Biotechnology

    International Nuclear Information System (INIS)


    The guidelines of the Biotechnology Program are research and development aiming at developing and manufacturing products of pharmaceutical interest. This Program has two main research areas, namely Pituitary Hormones and Biopharmaceuticals. The first one comprises a group with a long experience on Recombinant Human Pituitary Hormone synthesis, purification and characterization. Up to now they have worked mostly with human growth hormone (hGH), human prolactin (hPRL), human thyrotropin (hTSH), human follicle stimulating hormone (hFSH) and human luteotropin (hLH), with a particular emphasis on glycoprotein carbohydrate structures. An important research line is devoted to Growth Hormone Gene Therapy, working mostly on animal models: immunocompetent and immunodeficient-dwarf mice. For several years this development has been based on ex vivo grafting of transduced keratinocytes, while more recently very promising results have been obtained with the injections and electroporation of naked plasmid DNA. Besides research, they have also activities in the Biotechnological Production and Downstream Processing of the same recombinant hormones, which are produced in both E. coli and mammalian cells and in the development of joint-ventures with the National Industry. The biological effects of radiation on cells are also studied, specially concerning the administration of 131 I together with thyroid-stimulating hormone in thyroid cancer. The Biopharmaceutical area is dedicated to the research of isolation, structural analysis and biological activities in different biological systems of macromolecules. These macromolecules are peptides or proteins, either native or recombinant with medical or pharmaceutical interest. During this period new proteins related to serine protease activity, breast cancer development and angiogenesis were described. The effects of ionizing radiation on macromolecules have also been investigated to detoxify animal venoms in order to improve antigens for

  10. Underground mining operation supports

    Energy Technology Data Exchange (ETDEWEB)

    Khusid, M.B.; Kozel, A.M.


    Underground mining operation supports include the supporting layer surrounded by a cylindrical jacket of cemented rock. To decrease the loss of support material due to the decreasing rock pressure on the supporting layer, the cylindrical jacket of cemented rock has an uncemented layer inside, dividing it into 2 concentric cylindrical parts.

  11. Near universal support for covalent immobilisation of enzymes for biotechnology

    International Nuclear Information System (INIS)

    Elnashar, M.M.; Millner, P.A.; Gibson, T.D.


    Carrageenan [1], natural polymer, has been modified to be used as a universal/near universal support to immobilise enzymes, where the gel remained stable at 70 degree C for 24 h at a wide range of buffers and ph s and its mechanical strength was 400% greater than the unmodified gel. The new matrix successfully immobilised covalently eight commercially used enzymes including hydrolases, Upases, oxidoreductases, proteases and dehydrogenases. It also acted as a self buffering system in case of hydrolases and stopped enzyme's product inhibition. The apparent Km values of immobilised enzymes were found in many cases to be much less than those of the free enzymes. Another interesting correlation was observed where the great lowering of the apparent Km with immobilised enzymes was directly proportional to the substrate molecular weight. In economic terms, the new matrix is at least two orders of magnitude cheaper than supports such as Eupergit C

  12. 78 FR 72572 - Operational Contract Support (United States)


    ... 0790-AI48 Operational Contract Support AGENCY: Department of Defense (DoD). ACTION: Final rule. SUMMARY... contract support (OCS), including OCS program management, contract support integration, and integration of..., Director, Operational Contract Support Policy, Office of the Deputy Assistance Secretary of Defense...

  13. Operating-system support for distributed multimedia

    NARCIS (Netherlands)

    Mullender, Sape J.; Leslie, Ian M.; McAuley, Derek


    Multimedia applications place new demands upon processors, networks and operating systems. While some network designers, through ATM for example, have considered revolutionary approaches to supporting multimedia, the same cannot be said for operating systems designers. Most work is evolutionary in

  14. The DIAMOND Model of Peace Support Operations

    National Research Council Canada - National Science Library

    Bailey, Peter


    DIAMOND (Diplomatic And Military Operations in a Non-warfighting Domain) is a high-level stochastic simulation developed at Dstl as a key centerpiece within the Peace Support Operations (PSO) 'modelling jigsaw...

  15. Operating-System Support for Distributed Multimedia

    NARCIS (Netherlands)

    Mullender, Sape J.; Leslie, Ian M.; McAuley, Derek


    Multimedia applications place new demands upon processors, networks and operating systems. While some network designers, through ATM for example, have considered revolutionary approaches to supporting multimedia, the same cannot be said for operating systems designers. Most work is evolutionary in

  16. Manufacturers' support to plant operation

    International Nuclear Information System (INIS)

    Kuschel, D.


    For more than 30 years now, safety and availablity of German nuclear power plants has been a common interest of the plant owners and the manufacturing company KWU. This longstanding collaboration for a common goal has created a safety culture unprecented in other countries, and a partnership worth to be continued. Due to the nuclear power phaseout policy, the priority today is on maintaining and safeguarding economically efficient operation of existing power plants. KWU have been adapting their business strategy to the change in the market, and are prepared to stick to this line. Thus KWU and plant operators see to it that the acquired competence in nuclear power plant technology will remain to be concentrated in the hands of the manufacturers. Continuing the partnership in this field, and encouraged by the placement of orders for the future EPR and the SWR 1000, KWU and plant operators will be in the position to offer a sound option for future decisions about construction of new nuclear power plants in Germany. (orig.) [de

  17. Latin-American Co-operation in Biotechnology Programme: Industrial penicillin amidase for 6 amino penicillanic acid production

    Directory of Open Access Journals (Sweden)

    Dolly Montoya C.


    Full Text Available This work evaluates technological and economic transference related to the Production of Penicillin Amidase for use in 6 Amine Penicillanic acid (6-APA Production Project, wich is a part of the United Nations1 Regional Biotechnology Programme for Latin America and the Caribbean. This paper analyses the evolution of international cooperation by looking at the project's development. The methodology used includes analysis of: the project's development; participant and budgetary goals; results; copyright; project conditions; and sale of biocatalyst and 6-APA. All technical objectives were achieved; international co-operation, as well as co-operation between Industry and University were successful. Technological transference to the pilot plant was effective; many students involved in the project were simultaneously taking M.Sc. and Ph.D's courses. Nevertheless, neither the technology necessary for the biocatalyst's manufacture nor the biocatalyst itself were used. Analysis of the project has provided some orientation concerning those internal and external problems which arose during the development and sale of biotechnology in our countries and has tried to propose some alternatives for taking advantage of international co-operation.

  18. Development of JRR-4 operation support system

    International Nuclear Information System (INIS)

    Takahashi, Hiroki; Yamamoto, Kazuyoshi; Yoritsune, Tsutomu; Arai, Nobuyoshi; Birumachi, Takashi


    The Japan Research Reactor No.4 (JRR-4) is a light water moderated and cooled, graphite reflected, pool-type reactor with the thermal output of 3500 kW. In February 1996, a work on core modification from high-enriched fuels to low-enriched ones was started and the work on modification was completed in May 1998. As a part of the work, Operation Support System (OSS) was adopted for the purpose of reducing load of operator, preventing operator's error and supplying operation data to users. In this paper, JRR-4 Operation Support System's configuration, characteristics and development process are described. OSS consists mainly of a workstation (WS), μXL and Personal Computer (PC). WS is used for collection of operation data. μXL is used for cooling system control and PC is used for operators' support. All of the program applications used in WS, μXL and PC are designed to make sure of high flexibility for the demands on modification from operators and new operation modes. The result of adopting this system, the consolidation monitoring, automation of part of reactor operation and data management were realized. In addition, the cooling control system was compacted. (author)

  19. Aggregate assessments support improved operational decision making

    International Nuclear Information System (INIS)

    Bauer, R.


    At Darlington Nuclear aggregate assessment of plant conditions is carried out in support of Operational Decision Making. This paper discusses how aggregate assessments have been applied to Operator Workarounds leading to improved prioritisation and alignment of work programs in different departments. As well, aggregate assessment of plant and human performance factors has been carried out to identify criteria which support conservative decision making in the main control room during unit transients. (author)

  20. Operator support system for nuclear power plants

    International Nuclear Information System (INIS)

    Mori, Nobuyuki; Tai, Ichiro; Sudo, Osamu; Naito, Norio.


    The nuclear power generation in Japan maintains the high capacity factor, and its proportion taken in the total generated electric power exceeded 1/4, thus it has become the indispensable energy source. Recently moreover, the nuclear power plants which are harmonious with operators and easy to operate are demanded. For realizing this, the technical development such as the heightening of operation watching performance, the adoption of automation, and the improvement of various man-machine systems for reducing the burden of operators has been advanced by utilizing electronic techniques. In this paper, the trend of the man-machine systems in nuclear power plants, the positioning of operation support system, the support in the aspects of information, action and knowledge, the example of a new central control board, the operation support system using a computer, an operation support expert system and the problems hereafter are described. As the development of the man-machine system in nuclear power plants, the upgrading from a present new central control board system PODIA through A-PODIA, in which the operational function to deal with various phenomena arising in plants and safety control function are added, to 1-PODIA, in which knowledge engineering technology is adopted, is expected. (Kako, I.)

  1. Supporting CANDU operators-CANDU owners group

    International Nuclear Information System (INIS)

    Collingwood, B.R.


    The CANDU Owners Group (COG) was formed in 1984 by the Canadian CANDU owning utilities and Atomic Energy of Canada limited (AECL). Participation was subsequently extended to all CANDU owners world-wide. The mandate of the COG organization is to provide a framework for co-operation, mutual assistance and exchange of information for the successful support, development, operation, maintenance and economics of CANDU nuclear electric generating stations. To meet these objectives COG established co-operative programs in two areas: 1. Station Support. 2. Research and Development. In addition, joint projects are administered by COG on a case by case basis where CANDU owners can benefit from sharing of costs

  2. Operator Support System for Pressurized Water Reactor

    International Nuclear Information System (INIS)

    Wei Renjie; Shen Shifei


    Operator Support System for Pressurized Water Reactor (OSSPWR) has been developed under the sponsorship of IAEA from August 1994. The project is being carried out by the Department of Engineering Physics, Tsinghua University, Beijing, China. The Design concepts of the operator support functions have been established. The prototype systems of OSSPWR has been developed as well. The primary goal of the project is to create an advanced operator support system by applying new technologies such as artificial intelligence (AI) techniques, advanced communication technologies, etc. Recently, the advanced man-machine interface for nuclear power plant operators has been developed. It is connected to the modern computer systems and utilizes new high performance graphic displays. (author). 6 refs, 4 figs

  3. Requirements by the operator of supporting systems

    International Nuclear Information System (INIS)

    Grimm, E.; Lot, L.


    Requirements by the nuclear power station operator on computer support orient themselves to the various operating situations which can arise in the plant. Event-oriented or system-oriented methods of handling determine the type of support by the computer. Pure plant information in situations with few events, an intelligent alarm system in situations with many events and a guide by means of pre-prepared procedures are an aspect of the operator requirements of computer solutions. These are the themes dealt with in this paper. A further theme is the support of the operator by the ergonomics of the control room in the areas of working place, lighting, air conditioning and acoustics. (author) 4 figs

  4. AECL's support to operating plants world wide

    International Nuclear Information System (INIS)

    Azeez, S.; Kakaria, B.K.; Hinchley, E.M.


    Through their operating records, CANDU reactors have established themselves as a successful and cost-effective source of electricity in Canada and abroad. They have proven to be safe, reliable and economical. A variety of factors have contributed to the enviable CANDU record, such as a sound design based on proven principles supported by effective development programs, along with dedicated plant owners committed to excellence in safely maintaining and operating their plants. Atomic Energy of Canada Limited (AECL), the CANDU designer, has continuously maintained a close relationship with owners/operators of the plants in Canada, Argentina, Romania and South Korea. AECL and the plant operators have all benefited from this strengthening relationship by sharing experience and information. CANDU plant operators have been required to respond decisively to the economic realities of downward cost pressures and deregulation. Operating, Maintenance and Administration (OM and A) costs are being given a new focus as plant owners review each cost element to improve the economic returns from their investments. Amongst the three main OM and A constituents, plant maintenance costs are the most variable and have the largest influence on effective plant operations. The correlation between effective plant maintenance and high capacity factors shows clearly the importance of proactive maintenance planning to reduce the frequency and duration of forced plant outages and their negative impacts on plant economics. This paper describes the management processes and organizational structures m AECL that support plant operations and maintenance in operating CANDU plants with cost effective products and services. (author)

  5. The Biotechnology Facility for International Space Station (United States)

    Goodwin, Thomas; Lundquist, Charles; Hurlbert, Katy; Tuxhorn, Jennifer


    The primary mission of the Cellular Biotechnology Program is to advance microgravity as a tool in basic and applied cell biology. The microgravity environment can be used to study fundamental principles of cell biology and to achieve specific applications such as tissue engineering. The Biotechnology Facility (BTF) will provide a state-of-the-art facility to perform cellular biotechnology research onboard the International Space Station (ISS). The BTF will support continuous operation, which will allow performance of long-duration experiments and will significantly increase the on-orbit science throughput. With the BTF, dedicated ground support, and a community of investigators, the goals of the Cellular Biotechnology Program at Johnson Space Center are to: Support approximately 400 typical investigator experiments during the nominal design life of BTF (10 years). Support a steady increase in investigations per year, starting with stationary bioreactor experiments and adding rotating bioreactor experiments at a later date. Support at least 80% of all new cellular biotechnology investigations selected through the NASA Research Announcement (NRA) process. Modular components - to allow sequential and continuous experiment operations without cross-contamination Increased cold storage capability (+4 C, -80 C, -180 C). Storage of frozen cell culture inoculum - to allow sequential investigations. Storage of post-experiment samples - for return of high quality samples. Increased number of cell cultures per investigation, with replicates - to provide sufficient number of samples for data analysis and publication of results in peer-reviewed scientific journals.

  6. Towards Intelligent Operator Interfaces in Support of Autonomous UVS Operations (United States)


    Expressiveness: of all relevant actions to be performed by real, simulated or robotic forces. Intended to generate ATO, or to express the NATO 5...operator intervention to support other automation management strategies (e.g. takeover to manual control for Time-Sensitive Targeting and subsequent

  7. Technical support for nuclear power operations

    International Nuclear Information System (INIS)


    This report prepared by the group of senior experts from nuclear operating organizations in Member states, addresses the problem of improving the operating performance of nuclear power plants. Safe and reliable operation is essential for strengthening the viability of nuclear power in the increasingly competitive market of electric power. Basic principles and requirements concerning technical procedures and developed practices are discussed. Report reflects the best current international practices and presents those management initiatives that go beyond the mandated regulatory compliance and could lead to enhancement od operational safety and improved plant performance. By correlating experiences and presenting collective effective practices it is meant to assist nuclear power plant managers in achieving improvement in operation through the contribution of effective technical support

  8. 76 FR 81807 - Operational Contract Support (United States)


    ... Forces Overseas During Declared War and in Contingency Operations,'' dated March 10, 2008 (see http://www... Defense Acquisition University to offer education for all contingency contracting personnel. (9... oversight of training and education of non-acquisition, non-contracting personnel identified to support OCS...

  9. Operator support systems activities at EPRI

    International Nuclear Information System (INIS)

    Naser, J.A.


    The integration of operator support systems supports the nuclear power plant goals of improved availability and reliability, enhanced safety, reduced operations and maintenance costs, and improved productivity. Two major aspects which supports this integration are discussed in this paper. The first is the plant communications and computing architecture which provides the infrastructure that allows the integration to exist in a easy to implement manner. Open systems concepts are utilized to guarantee interoperability of systems and interchangeability of equipment. The second is the EPRI Plant-Window System which supplies the interface between the human and the plant systems. It implements common human-machine interfaces amongst systems and supports the implementation of diagnostic and decision aids. Work in both of these areas is being done as part of the EPRI Instrumentation and Control Upgrade Program. A number of operator support systems have been developed and are in various stages of implementation, testing and utilization. Two of these, the RWCU and the EOPTS, are described here. 5 refs, 14 figs


    Energy Technology Data Exchange (ETDEWEB)

    Thomas A. Ulrich; Roger Lew; Ronald L. Boring; Ken Thomas


    A computerized operator support system (COSS) is proposed for use in nuclear power plants to assist control room operators in addressing time-critical plant upsets. A COSS is a collection of technologies to assist operators in monitoring overall plant performance and making timely, informed decisions on appropriate control actions for the projected plant condition. A prototype COSS was developed in order to demonstrate the concept and provide a test bed for further research. The prototype is based on four underlying elements consisting of a digital alarm system, computer-based procedures, piping and instrumentation diagram system representations, and a recommender module for mitigation actions. The initial version of the prototype is now operational at the Idaho National Laboratory using the Human System Simulation Laboratory.

  11. MSFC Technical Support Team in the Huntsville Support Operations Center (United States)


    NASA and Hubble Space Telescope (HST) contractor employees monitor their data screens in the Huntsville Support Operations Center during a recent HST mission simulation at the Marshall Space Flight Center (MSFC) in Huntsville, Alabama. The Center will have a major role in the launch, deployment, and checkout of the HST in April 1990. The technicians will monitor telescope telemetry, tracking several thousand engineering measurements to determine the ongoing status of the HST and to confirm whether the telescope has responded properly to ground commands sent from the control center at the Goddard Space Flight Center (GSFC). With the information they receive, they can identify problems if they arise. Also, they will use their in-depth knowledge of the telescope and its systems to analyze problems and recommend ways to resolve them. Thirdly, they will evaluate HST performance to determine its true capabilities and project its future performance. Huntsville Support Operations Center will p

  12. Intelligence system for reactor operator informational support

    International Nuclear Information System (INIS)

    Prangishvili, I.V.; Pashchenko, F.F.; Saprykin, E.M.


    Problems related to creation and introduction at NPP of highly efficient and reliable systems for monitoring and control of working processes and intelligence-endowed systems of operator informational support (ISOIS) are considered. The main units included in ISOIS are considered. The main units included in ISOIS are described. The unit of current state monitoring provides information for the operator, which is necessary under concrete conditions for the process monitoring and control, so as to avoid emergencies and affers a program of actions in a dialogue mode for the operator. The identification unit is designed for the obtaining of assessed values of process parameters (neutron fields, temperatures, pressures) and basic equipment (reactivity coefficients, fuel rod weights, time of delay). The prediction unit evaluates the behaviour of process parameters and process state in various situations. 9 refs

  13. IGENPRO knowledge-based operator support system

    International Nuclear Information System (INIS)

    Morman, J. A.


    Research and development is being performed on the knowledge-based IGENPRO operator support package for plant transient diagnostics and management to provide operator assistance during off-normal plant transient conditions. A generic thermal-hydraulic (T-H) first-principles approach is being implemented using automated reasoning, artificial neural networks and fuzzy logic to produce a generic T-H system-independent/plant-independent package. The IGENPRO package has a modular structure composed of three modules: the transient trend analysis module PROTREN, the process diagnostics module PRODIAG and the process management module PROMANA. Cooperative research and development work has focused on the PRODIAG diagnostic module of the IGENPRO package and the operator training matrix of transients used at the Braidwood Pressurized Water Reactor station. Promising simulator testing results with PRODIAG have been obtained for the Braidwood Chemical and Volume Control System (CVCS), and the Component Cooling Water System. Initial CVCS test results have also been obtained for the PROTREN module. The PROMANA effort also involves the CVCS. Future work will be focused on the long-term, slow and mild degradation transients where diagnoses of incipient T-H component failure prior to forced outage events is required. This will enhance the capability of the IGENPRO system as a predictive maintenance tool for plant staff and operator support

  14. Cultural intelligence support for military operations

    Energy Technology Data Exchange (ETDEWEB)

    Guthormsen, Amy M. [Los Alamos National Laboratory; MacKerrow, Edward P [Los Alamos National Laboratory; Merritt, Terence M [Los Alamos National Laboratory; Morgart, Ruth E [INTERNATIONAL ATOMIC ENERGY


    It has long been recognized that military success relies on knowledge of the enemy. In the context of standard warfare, adequate knowledge of the enemy may be gained by analyzing observable, measurable data. In the context of modern counterinsurgency operations and the global war on terror, the task of predicting the behavior of the enemy is vastly more complex and difficult. Without an understanding of the ways individuals in the host nation interpret and react to events, no amount of objective information can provide the insight required to accurately predict behavior. US military doctrine has begun to recognize the importance of the many ways that local culture can affect operation success. Increasingly military decision makers use cultural information in the service of operation planning, and troops are provided with pre-deployment cultural training. However, no amount of training can cover the breadth and depth of potentially useful cultural information, and no amount of careful planning can avoid the need to adapt as situations develop. Therefore, a critical challenge is to provide useful tools to US personnel in their efforts to collect, analyze, and utilize cultural information. Essential functions for cultural support tools include the following: (1) to narrow down a broad range of available data and focus the user's attention on context-relevant information, (2) to present cultural information in an easily understood form, (3) to prompt the user to seek relevant information in the environment, (4) to synthesize information, and (5) to predict outcomes based on possible courses of operation. In this paper, we begin by reviewing the ways in which military operations can benefit from cultural intelligence. We then discuss frameworks for analyzing cultural information in the context of a military operation. We conclude with a demonstration of our current efforts to develop a tool that meets the aforementioned functional challenges.

  15. A Computuerized Operator Support System Prototype

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, Ken [Idaho National Lab. (INL), Idaho Falls, ID (United States); Boring, Ronald [Idaho National Lab. (INL), Idaho Falls, ID (United States); Lew, Roger [Idaho National Lab. (INL), Idaho Falls, ID (United States); Ulrich, Tom [Idaho National Lab. (INL), Idaho Falls, ID (United States); Villim, Richard [Idaho National Lab. (INL), Idaho Falls, ID (United States)


    A report was published by the Idaho National Laboratory in September of 2012, entitled Design to Achieve Fault Tolerance and Resilience, which described the benefits of automating operator actions for transients. The report identified situations in which providing additional automation in lieu of operator actions would be advantageous. It recognized that managing certain plant upsets is sometimes limited by the operator’s ability to quickly diagnose the fault and to take the needed actions in the time available. Undoubtedly, technology is underutilized in the nuclear power industry for operator assistance during plant faults and operating transients. In contrast, other industry sectors have amply demonstrated that various forms of operator advisory systems can enhance operator performance while maintaining the role and responsibility of the operator as the independent and ultimate decision-maker. A computerized operator support system (COSS) is proposed for use in nuclear power plants to assist control room operators in addressing time-critical plant upsets. A COSS is a collection of technologies to assist operators in monitoring overall plant performance and making timely, informed decisions on appropriate control actions for the projected plant condition. The COSS does not supplant the role of the operator, but rather provides rapid assessments, computations, and recommendations to reduce workload and augment operator judgment and decision-making during fast-moving, complex events. This project proposes a general model for a control room COSS that addresses a sequence of general tasks required to manage any plant upset: detection, validation, diagnosis, recommendation, monitoring, and recovery. The model serves as a framework for assembling a set of technologies that can be interrelated to assist with each of these tasks. A prototype COSS has been developed in order to demonstrate the concept and provide a test bed for further research. The prototype is based

  16. A Computuerized Operator Support System Prototype

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, Ken [Idaho National Lab. (INL), Idaho Falls, ID (United States); Boring, Ronald [Idaho National Lab. (INL), Idaho Falls, ID (United States); Lew, Roger [Idaho National Lab. (INL), Idaho Falls, ID (United States); Ulrich, Tom [Idaho National Lab. (INL), Idaho Falls, ID (United States); Villim, Richard [Idaho National Lab. (INL), Idaho Falls, ID (United States)


    A report was published by the Idaho National Laboratory in September of 2012, entitled Design to Achieve Fault Tolerance and Resilience, which described the benefits of automating operator actions for transients. The report identified situations in which providing additional automation in lieu of operator actions would be advantageous. It recognized that managing certain plant upsets is sometimes limited by the operator’s ability to quickly diagnose the fault and to take the needed actions in the time available. Undoubtedly, technology is underutilized in the nuclear power industry for operator assistance during plant faults and operating transients. In contrast, other industry sectors have amply demonstrated that various forms of operator advisory systems can enhance operator performance while maintaining the role and responsibility of the operator as the independent and ultimate decision-maker. A computerized operator support system (COSS) is proposed for use in nuclear power plants to assist control room operators in addressing time-critical plant upsets. A COSS is a collection of technologies to assist operators in monitoring overall plant performance and making timely, informed decisions on appropriate control actions for the projected plant condition. The COSS does not supplant the role of the operator, but rather provides rapid assessments, computations, and recommendations to reduce workload and augment operator judgment and decision-making during fast-moving, complex events. This project proposes a general model for a control room COSS that addresses a sequence of general tasks required to manage any plant upset: detection, validation, diagnosis, recommendation, monitoring, and recovery. The model serves as a framework for assembling a set of technologies that can be interrelated to assist with each of these tasks. A prototype COSS has been developed in order to demonstrate the concept and provide a test bed for further research. The prototype is based

  17. Operator support system using computational intelligence techniques

    International Nuclear Information System (INIS)

    Bueno, Elaine Inacio; Pereira, Iraci Martinez


    Computational Intelligence Systems have been widely applied in Monitoring and Fault Detection Systems in several processes and in different kinds of applications. These systems use interdependent components ordered in modules. It is a typical behavior of such systems to ensure early detection and diagnosis of faults. Monitoring and Fault Detection Techniques can be divided into two categories: estimative and pattern recognition methods. The estimative methods use a mathematical model, which describes the process behavior. The pattern recognition methods use a database to describe the process. In this work, an operator support system using Computational Intelligence Techniques was developed. This system will show the information obtained by different CI techniques in order to help operators to take decision in real time and guide them in the fault diagnosis before the normal alarm limits are reached. (author)

  18. An intelligent ground operator support system (United States)

    Goerlach, Thomas; Ohlendorf, Gerhard; Plassmeier, Frank; Bruege, Uwe


    This paper presents first results of the project 'Technologien fuer die intelligente Kontrolle von Raumfahrzeugen' (TIKON). The TIKON objective was the demonstration of feasibility and profit of the application of artificial intelligence in the space business. For that purpose a prototype system has been developed and implemented for the operation support of the Roentgen Satellite (ROSAT), a scientific spacecraft designed to perform the first all-sky survey with a high-resolution X-ray telescope and to investigate the emission of specific celestial sources. The prototype integrates a scheduler and a diagnosis tool both based on artificial intelligence techniques. The user interface is menu driven and provides synoptic displays for the visualization of the system status. The prototype has been used and tested in parallel to an already existing operational system.

  19. Operator support system using computational intelligence techniques

    Energy Technology Data Exchange (ETDEWEB)

    Bueno, Elaine Inacio, E-mail: [Instituto Federal de Educacao, Ciencia e Tecnologia de Sao Paulo (IFSP), Sao Paulo, SP (Brazil); Pereira, Iraci Martinez, E-mail: [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)


    Computational Intelligence Systems have been widely applied in Monitoring and Fault Detection Systems in several processes and in different kinds of applications. These systems use interdependent components ordered in modules. It is a typical behavior of such systems to ensure early detection and diagnosis of faults. Monitoring and Fault Detection Techniques can be divided into two categories: estimative and pattern recognition methods. The estimative methods use a mathematical model, which describes the process behavior. The pattern recognition methods use a database to describe the process. In this work, an operator support system using Computational Intelligence Techniques was developed. This system will show the information obtained by different CI techniques in order to help operators to take decision in real time and guide them in the fault diagnosis before the normal alarm limits are reached. (author)

  20. Operations Plan for Support Network Development

    Energy Technology Data Exchange (ETDEWEB)



    This report describes the operational processes and strategies that are building a support network for the National Security Technology Incubator (NSTI) program. The NSTI program currently is under development as part of the National Security Preparedness Project (NSPP), funded by Department of Energy (DOE)/National Nuclear Security Administration (NNSA) Grant No. DE FG52-07NA28084. Although the NSTI program offers a wide array of in-house business services, there are a certain number of services that will be provided by entities outside of Arrowhead Center. This report identifies the steps needed to develop an appropriate support network. The Arrowhead Center is working with external service providers and key stakeholders to establish feasible referral and implementation mechanics offering NSTI program participants the most comprehensive incubation services possible.

  1. How to guide - transit operations decision support systems (TODSS). (United States)


    Transit Operations Decision Support Systems (TODSS) are decision support systems designed to support dispatchers in real-time bus operations : management in response to incidents, special events, and other changing conditions in order to restore serv...

  2. Technical and operational feasibility of psychrophilic anaerobic digestion biotechnology for processing ammonia-rich waste

    International Nuclear Information System (INIS)

    Massé, Daniel I.; Rajagopal, Rajinikanth; Singh, Gursharan


    Highlights: • Long-term anaerobic digestion (AD) process at high-ammonia (>5 gN/L) is limited. • PADSBR technology was validated to treat N-rich waste with 8.2 ± 0.3 gNH 3 -N/L. • Excess ammonia (8.2 gN/L) did not affect the digestion process with no inhibition. • VFA, an indicator for process stability, did not accumulate in PADSBR. • Biomass acclimation in PADSBR ensured a high-stabilization of the AD process. - Abstract: Ammonia nitrogen plays a critical role in the performance and stability of anaerobic digestion (AD) of ammonia rich wastes like animal manure. Nevertheless, inhibition due to high ammonia remains an acute limitation in AD process. A successful long-term operation of AD process at high ammonia (>5 gN/L) is limited. This study focused on validating technical feasibility of psychrophilic AD in sequencing batch reactor (PADSBR) to treat swine manure spiked with NH 4 Cl up to 8.2 ± 0.3 gN/L, as a representative of N-rich waste. CODt, CODs, VS removals of 86 ± 3, 82 ± 2 and 73 ± 3% were attained at an OLR of 3 gCOD/L.d, respectively. High-ammonia had no effect on methane yields (0.23 ± 0.04 L CH 4 /gTCOD fed ) and comparable to that of control reactors, which fed with raw swine manure alone (5.5 gN/L). Longer solids/hydraulic retention times in PADSBRs enhanced biomass acclimation even at high-ammonia. Thus VFA, an indicator for process stability, did not accumulate in PADSBR. Further investigation is essential to establish the maximum concentrations of TKN and free ammonia that the PADSBR can sustain

  3. ARAC's operational support of the Cassini launch (United States)

    Pace, John C.; Baskett, Ronald L.


    The Atmospheric Release Advisory Capability (ARAC) program at the Lawrence Livermore National Laboratory (LLNL) was the U.S. Department of Energy atmospheric modeling resource used for the contingency of potential radiological releases during the launch of the Cassini mission. The ARAC Center at LLNL forecasted detailed weather conditions and delivered consequence assessments for potential accident scenarios to NASA before and during launch operations. A key aspect of ARAC's support was to acquire a variety of meteorological data for use in both forecast and real-time model calculations. ARAC acquired electronically two types of real-time observed meteorological data: 1) the full set of on-site towers and profilers via the Cape Canaveral Air Station (CCAS) Meteorological Interactive Data Display System (MIDDS), and 2) routine regional airport observations (delivered to the ARAC Center from the Air Force Weather Agency). We also used two forecasted data sources: 1) the U.S. Air Force 45th Weather Squadron at CCAS forecasted soundings for launch time, and 2) the Navy Operational Regional Atmospheric Prediction System (NORAPS) prognostic model which ARAC ran over the Cape. The NORAPS runs produced detailed 24-hr forecasts of 3-D wind fields. ARAC used default radiological accident source terms involving the potential destruction of Cassini's Radioisotope Thermoelectric Generators (RTGs) during 3 phases: 1) before the launch, 2) during the first 5 sec after ignition, and 3) from 5 to 143 sec after ignition. ARAC successfully developed and delivered dose and deposition plots at 24 hours, 3 hours, and 30 minutes before each of the launch windows.

  4. Medical Operations Support for ISS Operations - The Role of the BME Operations Team Leads (United States)

    Janney, Rob; Sabatier, Veronica


    This slide presentation reviews the role of the biomedical flight controllers (BMEs), and BME Operations Team Leads (OTLs) in providing medical support for personnel on the International Space Station. This presentation will concentrate on role of the BME OTLs, who provide the integration function across the integration function across all Crew Health Care System (CHeCS) disciplines for operational products and medical procedures.

  5. Agent-Supported Mission Operations Teamwork (United States)

    Malin, Jane T.


    This slide presentation reviews the development of software agents to support of mission operations teamwork. The goals of the work was to make automation by agents easy to use, supervise and direct, manage information and communication to decrease distraction, interruptions, workload and errors, reduce mission impact of off-nominal situations and increase morale and decrease turnover. The accomplishments or the project are: 1. Collaborative agents - mixed initiative and creation of instructions for mediating agent 2. Methods for prototyping, evaluating and evolving socio-technical systems 3. Technology infusion: teamwork tools in mISSIons 4. Demonstrations in simulation testbed An example of the use of agent is given, the use of an agent to monitor a N2 tank leak. An incomplete instruction to the agent is handled with mediating assistants, or Intelligent Briefing and Response Assistant (IBRA). The IBRA Engine also watches data stream for triggers and executes Act-Whenever actions. There is also a Briefing and Response Instruction (BRI) which is easy for a discipline specialist to create through a BRI editor.

  6. Overcoming Information Operations Legal Limitations in Support of Domestic Operations (United States)


    Katrina Update Brief, 24 2200Z SEP 05. US Army Corps of Engineers (USACE). USACE Operations Center ( UOC ) Update Brief, 23 0900 September 2005...USA CGSC, July,2006. US Army Corps of Engineers (USACE). USACE Operations Center ( UOC ) Update Brief, 23 0900 September 2005. USCENTCOM J3

  7. Biotechnology bibliographies

    Energy Technology Data Exchange (ETDEWEB)

    Beaudette, L.A.; McCready, R.G.L.


    This bibliography consists of articles and scientific papers on biotechnology in areas in which BIOMINET is currently involved. The reports are categorized in four areas: 1) acid mine drainage (coals and metals) and bioadsorption of metals; 2) solution mining; 3) metabolism and physiology of Thiobacillus and other microorganisms; and 4) bacterial leaching of metals.

  8. Operating experience insights supporting ageing assessments

    International Nuclear Information System (INIS)

    Nitoi, M.


    Be effective in ageing management means looking at the right aspects, with the right techniques, and one of the most effective tool which could be used for that purpose is the analysis of operating experience. The paper has as objective to perform a review of available operating experience, with the aim to provide a better picture about the impact of ageing effects. The IAEA International Reporting System and NRC Licensee Event Reports were chosen as reference databases, both databases being internationally recognized as important sources of information about events occurrences in the nuclear power plants. The ageing related events identified in the selected time window were analyzed in detail, and the contributions of each major degradation mechanisms that have induced the ageing related events (specific to each defined group of components) was represented and discussed. The paper demonstrates the possibility to use operating experience insights in highlighting the ageing effects. (authors)

  9. A diagnosis system for plant operation support

    International Nuclear Information System (INIS)

    Sundheimer, S.; Lorenzetti, J.; Lamana, C.


    The present article describes a diagnosis system for abnormal power plant events. The design is modular and uses a shell written in C languaje and a knowledge basis that can be changed easily. At present the system works with a reduced knowledge for primary and secondery leacks. The mitigation procedure is being written with the help of operation staff

  10. Operating System Support for Mobile Interactive Applications (United States)


    Arpaci, and David E. Culler . Effective distributed scheduling of parallel workloads. In Proceedings of the Joint International Con- ference on Measurement... Jonathan Walpole. A feedback-driven proportion allocator for real-rate scheduling. In Proceedings of the 3rd Symposium on Operating Systems Design and



    Bradut-Vasile BOLOS; Hesham MAGD


    In this paper we attempt to model a moudaraba inspired financing system for SME support, especially for start-ups, using public funding as high-risk investments instead of grants. The model obtained suggests such an approach may prove to be more efficient, but further research is required.

  12. Supporting plant operation through computer-based procedures

    International Nuclear Information System (INIS)

    Martinez, Victor; Medrano, Javier; Mendez, Julio


    Digital Systems are becoming more important in controlling and monitoring nuclear power plant operations. The capabilities of these systems provide additional functions as well as support operators in making decisions and avoiding errors. Regarding Operation Support Systems, an important way of taking advantage of these features is using computer-based procedures (CBPs) tools that enhance the plant operation. Integrating digital systems in analogue controls at nuclear power plants in operation becomes an extra challenge, in contrast to the integration of Digital Control Systems in new nuclear power plants. Considering the potential advantages of using this technology, Tecnatom has designed and developed a CBP platform taking currently operating nuclear power plants as its design basis. The result is a powerful tool which combines the advantages of CBPs and the conventional analogue control systems minimizing negative effects during plant operation and integrating operation aid-systems to support operators. (authors)

  13. Avian Biotechnology. (United States)

    Nakamura, Yoshiaki


    Primordial germ cells (PGCs) generate new individuals through differentiation, maturation and fertilization. This means that the manipulation of PGCs is directly linked to the manipulation of individuals, making PGCs attractive target cells in the animal biotechnology field. A unique biological property of avian PGCs is that they circulate temporarily in the vasculature during early development, and this allows us to access and manipulate avian germ lines. Following the development of a technique for transplantation, PGCs have become central to avian biotechnology, in contrast to the use of embryo manipulation and subsequent transfer to foster mothers, as in mammalian biotechnology. Today, avian PGC transplantation combined with recent advanced manipulation techniques, including cell purification, cryopreservation, depletion, and long-term culture in vitro, have enabled the establishment of genetically modified poultry lines and ex-situ conservation of poultry genetic resources. This chapter introduces the principles, history, and procedures of producing avian germline chimeras by transplantation of PGCs, and the current status of avian germline modification as well as germplasm cryopreservation. Other fundamental avian reproductive technologies are described, including artificial insemination and embryo culture, and perspectives of industrial applications in agriculture and pharmacy are considered, including poultry productivity improvement, egg modification, disease resistance impairment and poultry gene "pharming" as well as gene banking.

  14. Performance Support Tools for Space Medical Operations (United States)

    Byrne, Vicky E.; Schmidt, Josef; Barshi, Immanuel


    The early Constellation space missions are expected to have medical capabilities very similar to those currently on the Space Shuttle and International Space Station (ISS). For Crew Exploration Vehicle (CEV) missions to ISS, medical equipment will be located on ISS, and carried into CEV in the event of an emergency. Flight Surgeons (FS) on the ground in Mission Control will be expected to direct the Crew Medical Officer (CMO) during medical situations. If there is a loss of signal and the crew is unable to communicate with the ground, a CMO would be expected to carry out medical procedures without the aid of a FS. In these situations, performance support tools can be used to reduce errors and time to perform emergency medical tasks. Human factors personnel at Johnson Space Center have recently investigated medical performance support tools for CMOs on-orbit, and FSs on the ground. This area of research involved the feasibility of Just-in-time (JIT) training techniques and concepts for real-time medical procedures. In Phase 1, preliminary feasibility data was gathered for two types of prototype display technologies: a hand-held PDA, and a Head Mounted Display (HMD). The PDA and HMD were compared while performing a simulated medical procedure using ISS flight-like medical equipment. Based on the outcome of Phase 1, including data on user preferences, further testing was completed using the PDA only. Phase 2 explored a wrist-mounted PDA, and compared it to a paper cue card. For each phase, time to complete procedures, errors, and user satisfaction were captured. Information needed by the FS during ISS mission support, especially for an emergency situation (e.g. fire onboard ISS), may be located in many different places around the FS s console. A performance support tool prototype is being developed to address this issue by bringing all of the relevant information together in one place. The tool is designed to include procedures and other information needed by a FS

  15. Computerized systems of NPP operators support. (Psychological problems)

    International Nuclear Information System (INIS)

    Mashin, V.A.


    Operator psychological problems arising in the work with NPP operators support computerized systems (OSCS) are considered. The conclusion is made that the OSCS intellectual application will bring the operator into dangerous dependence on his computerized assistant. To avoid this danger it is necessary by creation of the OSCS to divide specially the tasks areas of the operator and OSCS in order to assure the active role of the operator in the NPP control

  16. Development of operation support system for MOX fuel production line

    International Nuclear Information System (INIS)

    Gunji, Yasutoshi; Fujiwara, Shigeo; Iso, Hidetoshi; Suzuki, Yoshihiro; Shishido, Toshio


    Plutonium Fuel Production Facility (PFPF) FBR line started production of MOX fuels for 'JOYO' MK-II in October 1988. The production campaign for 'Monju' initial core fuel followed that for 'Joyo'. Control of this line is mainly computerized to allow remote operation. According to our test run experiences the automated plant, requires the higher judgement ability of operator when a problem arises. We need the plant which can be operated by even unskilled operator, on the technical level equal to that of skilled operator. This requirement will be satisfied by introduction of new support system into applying Artificial Intelligence technology based on operating experience. Now we have developed some operation support systems taking main aim at high efficiency of production for example, the optimum operation control system the failure diagnosis system and the production planning support system. (author)

  17. Technical and organizational support for the operator

    International Nuclear Information System (INIS)

    Harrison, J.R.; Prescott, W.


    The requirement for staff and facilities on- and off-site to provide technical support to the plant personnel in normal and under accident conditions has been highlighted over the past 18 months as part of the post-TMI investigations. In the Central Electricity Generating Board (CEGB) considerable attention has always been paid to these requirements but naturally the experience of TMI has led to a review of the existing arrangements to determine whether any improvements and modifications were advisable. Similarly, the CEGB has always paid particular attention to the development of an appropriate emergency plant covering both the on-site damage control activities and off-site evacuation procedures consistent with the demography of the particular site being considered. An important aspect of gaining confidence in the potential success of the emergency plan is the regular practice and exercising of individual parts of the plan and its totality, and full attention is given also to these aspects. The paper reviews in some detail the ways in which the CEGB has met the requirements for the different aspects enumerated above, and will trace the approaches which have developed in the training and practices in respect of accident procedures. (author)

  18. Logistics Operations Management Center: Maintenance Support Baseline (LOMC-MSB) (United States)

    Kurrus, R.; Stump, F.


    The Logistics Operations Management Center Maintenance Support Baseline is defined. A historical record of systems, applied to and deleted from, designs in support of future management and/or technical analysis is provided. All Flight elements, Ground Support Equipment, Facility Systems and Equipment and Test Support Equipment for which LOMC has responsibilities at Kennedy Space Center and other locations are listed. International Space Station Alpha Program documentation is supplemented. The responsibility of the Space Station Launch Site Support Office is established.

  19. State responses to biotechnology. (United States)

    Harris, Rebecca C


    This article reviews biotechnology legislation in the 50 states for 11 policy areas spanning 1990-2010, an era of immense growth in biotechnology, genetic knowledge, and significant policy development. Policies regarding health insurance, life insurance, long-term care insurance, DNA data bank collection, biotech research protection, biotech promotion and support, employment discrimination, genetic counselor licensing, human cloning, and genetic privacy each represent major policy responses arising from biotechnology and coinciding with key areas of state regulation (insurance, criminal justice, economic development, labor law, health and safety, privacy, and property rights). This analysis seeks to answer three questions regarding biotechnology legislation at the state level: who is acting (policy adoption), when is policy adopted (policy timing), and what is policy doing (policy content). Theoretical concerns examine state ideology (conservative or liberal), policy type (economic or moral), and the role of external events (federal law, news events, etc.) on state policy adoption. Findings suggest ideological patterns in adoption, timing, and content of biotech policy. Findings also suggest economic policies tend to be more uniform in content than moral policies, and findings also document a clear link between federal policy development, external events, and state policy response.

  20. IAEA activity on operator support systems in nuclear power plants

    International Nuclear Information System (INIS)

    Dounaev, V.; Fujita, Y.; Juslin, K.; Haugset, K.; Lux, I.; Naser, J.


    Various operator support systems for nuclear power plants are already operational or under development in the IAEA Member States. Operator support systems are based on intelligent data processing and, in addition to plant operation, they are also becoming more important for safety. A key feature of operator support systems is their availability to restructure data to increase its relevance for a given situation. This can improve the user's ability to identify plant mode, system state, and component state and to identify and diagnose faults. Operator support systems can also assist the user in planning and implementing corrective actions to improve the nuclear power plant's availability and safety. In September 1991, the IAEA Committee for Contractual Scientific Services approved the Co-ordinated Research Programme (CRP) on ''Operator Support Systems in Nuclear Power Plants'' in the framework of the Project ''Man-Machine Interface Studies''. The main objective of this programme is to provide guidance and technology transfer for the development and implementation of operator support systems. This includes the experience with human-machine interfaces and closely related issues such as instrumentation and control, the use of computers in nuclear power plants, and operator qualification. (author)

  1. Operator Support System Design forthe Operation of RSG-GAS Research Reactor (United States)

    Santoso, S.; Situmorang, J.; Bakhri, S.; Subekti, M.; Sunaryo, G. R.


    The components of RSG-GAS main control room are facing the problem of material ageing and technology obsolescence as well, and therefore the need for modernization and refurbishment are essential. The modernization in control room can be applied on the operator support system which bears the function in providing information for assisting the operator in conducting diagnosis and actions. The research purpose is to design an operator support system for RSG-GAS control room. The design was developed based on the operator requirement in conducting task operation scenarios and the reactor operation characteristics. These scenarios include power operation, low power operation and shutdown/scram reactor. The operator support system design is presented in a single computer display which contains structure and support system elements e.g. operation procedure, status of safety related components and operational requirements, operation limit condition of parameters, alarm information, and prognosis function. The prototype was developed using LabView software and consisted of components structure and features of the operator support system. Information of each component in the operator support system need to be completed before it can be applied and integrated in the RSG-GAS main control room.

  2. Review of Operation and Maintenance Support Systems for Research Reactors

    International Nuclear Information System (INIS)

    Jin, Kyungho; Heo, Gyunyoung; Park, Jaekwan


    Operation support systems do not directly control the plant but it can aid decision making itself by obtaining and analyzing large amounts of data. Recently, the demand of research reactor is growing and the need for operation support systems is increasing, but it has not been applied for research reactors. This study analyzes operation and maintenance support systems of NPPs and suggests appropriate systems for research reactors based on analysis. In this paper, operation support systems for research reactors are suggested by comparing with those of power reactors. Currently, research reactors do not cover special systems in order to improve safety and operability in comparison with power reactors. Therefore we expect to improve worth to use by introducing appropriate systems for research reactors. In further research, we will develop an appropriate system such as applications or tools that can be applied to the research reactor

  3. Computerized operator support system for the JMTR: ARGUS

    International Nuclear Information System (INIS)

    Oyamada, R.; Yamamoto, K.; Ishii, Y.; Sekine, N.; Nemoto, N.


    ARGUS is computerized operator support system developed for the JMTR Function keybords, alphanumic keybords, and colour display terminals serve as comminication interface between ARGUS and operating personnel. ARGUS serves the following purposes; 1) data logging, 2) early abnormality detection, 3) presenting relevant and concentrated information to the operators to support their accurate judgment in case of abnormality occurrence, 4) save of time-historical data for diagnostics, and 5) data base necessary for JMTR operation and maintenance. ARGUS has been implemented on a VAX-11/750 with mos memories of 7.25 MB. (author)

  4. Using Commercial Aviation Information Systems in Operational Support Airlift Decision Support Systems

    National Research Council Canada - National Science Library

    Kubik, Charles


    .... Decision Support Systems (DSS) can help manage these networks by attempting to create optimized scheduling solutions for routing aircraft, crews and logistical support needed to successfully operate in this new environment...

  5. Urban Combat Service Support Operations: The Shoulders of Atlas

    National Research Council Canada - National Science Library

    Glenn, Russell


    ... U.S. Army combat service support (CSS) community can prepare itself to meet them. The authors conclude that CSS operations, like other ground force undertakings, need not undergo fundamental changes simply because the environment is urban...

  6. The concept of information support system for operational personnel of operating NPPs

    International Nuclear Information System (INIS)

    Dunaev, V.G.; Golovanov, V.V.


    The paper has been prepared on the materials of the concept developed by the order of ''Rosenergoatom'' concern. In the present paper the main definitions, the principal objectives and functions of the operator support system (OSS) are stated, a brief analysis of operation features of some existing operator information systems is presented, the main trends of development of operator information support system are given, the way and the sequence for implementation of the systems for operating NPPs are reviewed. In this proposed concept in the first place are considered the information support systems for the operators of the power unit main control rooms, however, the presented principles may be applied while designing information support systems for operators of other control rooms of NPP. 4 refs

  7. Editorial: Biotechnology Journal brings more than biotechnology. (United States)

    Jungbauer, Alois; Lee, Sang Yup


    Biotechnology Journal always brings the state-of-the-art biotechnologies to our readers. Different from other topical issues, this issue of Biotechnology Journal is complied with a series of exiting reviews and research articles from spontaneous submissions, again, addressing society's actual problems and needs. The progress is a real testimony how biotechnology contributes to achievements in healthcare, better utilization of resources, and a bio-based economy. Copyright © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Editorial: Biotechnology Journal's diverse coverage of biotechnology. (United States)

    Wink, Michael


    This issue of Biotechnology Journal is a regular issue edited by Prof. Michael Wink. The issue covers all the major focus areas of the journal, including medical biotechnology, synthetic biology, and novel biotechnological methods. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  9. Development of lung cancer CT screening operating support system (United States)

    Ishigaki, Rikuta; Hanai, Kozou; Suzuki, Masahiro; Kawata, Yoshiki; Niki, Noboru; Eguchi, Kenji; Kakinuma, Ryutaro; Moriyama, Noriyuki


    In Japan, lung cancer death ranks first among men and third among women. Lung cancer death is increasing yearly, thus early detection and treatment are needed. For this reason, CT screening for lung cancer has been introduced. The CT screening services are roughly divided into three sections: office, radiology and diagnosis sections. These operations have been performed through paper-based or a combination of paper-based and an existing electronic health recording system. This paper describes an operating support system for lung cancer CT screening in order to make the screening services efficient. This operating support system is developed on the basis of 1) analysis of operating processes, 2) digitalization of operating information, and 3) visualization of operating information. The utilization of the system is evaluated through an actual application and users' survey questionnaire obtained from CT screening centers.

  10. Supporting Operational Data Assimilation Capabilities to the Research Community (United States)

    Shao, H.; Hu, M.; Stark, D. R.; Zhou, C.; Beck, J.; Ge, G.


    The Developmental Testbed Center (DTC), in partnership with the National Centers for Environmental Prediction (NCEP) and other operational and research institutions, provides operational data assimilation capabilities to the research community and helps transition research advances to operations. The primary data assimilation system supported currently by the DTC is the Gridpoint Statistical Interpolation (GSI) system and the National Oceanic and Atmospheric Administration (NOAA) Ensemble Kalman Filter (EnKF) system. GSI is a variational based system being used for daily operations at NOAA, NCEP, the National Aeronautics and Space Administration, and other operational agencies. Recently, GSI has evolved into a four-dimensional EnVar system. Since 2009, the DTC has been releasing the GSI code to the research community annually and providing user support. In addition to GSI, the DTC, in 2015, began supporting the ensemble based EnKF data assimilation system. EnKF shares the observation operator with GSI and therefore, just as GSI, can assimilate both conventional and non-conventional data (e.g., satellite radiance). Currently, EnKF is being implemented as part of the GSI based hybrid EnVar system for NCEP Global Forecast System operations. This paper will summarize the current code management and support framework for these two systems. Following that is a description of available community services and facilities. Also presented is the pathway for researchers to contribute their development to the daily operations of these data assimilation systems.

  11. An intelligent operator support system for Dynamic positioning

    NARCIS (Netherlands)

    Diggelen, J. van; Broek, J. van den; Schraagen, J.M.C.; Waa, J.S. van der


    This paper proposes a human-centered approach to Dynamic Positioning systems which combines multiple technologies in an intelligent operator support system (IOSS). IOSS allows the operator to be roaming and do other tasks in quiet conditions. When conditions become more demanding, the IOSS calls the

  12. An intelligent operator support system for dynamic positioning

    NARCIS (Netherlands)

    Diggelen, J. van; Broek, J. van den; Schraagen, J.M.C.; Waa, J.S. van der


    This paper proposes a human-centered approach to Dynamic Position-ing systems which combines multiple technologies in an intelligent operator sup-port system (IOSS). IOSS allows the operator to be roaming and do other tasks in quiet conditions. When conditions become more demanding, the IOSS calls

  13. SCOPE : an intelligent maintenance system for supporting crew operations

    NARCIS (Netherlands)

    Bos, A.; Breebaart, L.; Neerincx, M.A.; Wolff, M.


    This paper describes an intelligent maintenance system for Supporting Crew OPErations (SCOPE). SCOPE supports the astronauts onboard the ISS and helps them to maximize the availability of complex payload systems. SCOPE detects system failures, guides the isolation of the root causes of failure, and

  14. Real time operational support in young stock rearing

    NARCIS (Netherlands)

    Ipema, A.H.; Mol, de R.M.; Hogewerf, P.H.; Prins, Bram; Sijbrandij, Fedde; Winden, R.P.J.; Hanenberg, M.J.A.; Jorritsma, R.


    The aim of the Dutch Smart Dairy Farming project is to develop decision support models for operational support in farm management. This project started in 2012 and involves collaboration between several institutions and companies in the dairy chain. The project has three focus areas: animal health,

  15. Remote operation and maintenance support services for nuclear power plants

    International Nuclear Information System (INIS)

    Yamamoto, Hiroki; Higuma, Koji; Shimizu, Shunichi; Sakuma, Masatake; Sonoda, Yukio; Kanemoto, Shigeru


    Toshiba Corporation constructed e-Toshiba Operating Plant Service (e-TOPS TM ) system and began remote operation and maintenance support service for nuclear power plants. The service put into practice remote operation and maintenance by harmony of information technologies such as internet and mobile, and nuclear power measurement/diagnostic technologies and security techniques. Outline of e-TOPS TM , remote-control service, -inspection system, -diagnostic service and technologies support service are explained. Construction, objects and application effects of e-TOPS TM , remote diagnostic system using image treatment techniques, construction of device record card control system are illustrated. (S.Y.)

  16. Supporting Control Room Operators in Highly Automated Future Power Networks

    DEFF Research Database (Denmark)

    Chen, Minjiang; Catterson, Victoria; Syed, Mazheruddin


    Operating power systems is an extremely challenging task, not least because power systems have become highly interconnected, as well as the range of network issues that can occur. It is therefore a necessity to develop decision support systems and visualisation that can effectively support the hu...... the human operators for decisionmaking in the complex and dynamic environment of future highly automated power system. This paper aims to investigate the decision support functions associated with frequency deviation events for the proposed Web of Cells concept....

  17. Expert system for operational personnel support during power unit operation control in regulation range

    International Nuclear Information System (INIS)

    Yanitskij, V.A.


    The problems met when developing the systems for NPP operator support in the process of power unit operation are considered. The expert system for NPP personnel intelligent support combining the properties belonging to the artificial intelligence systems including selection of the analysis method taking into account the concrete technological situation and capability of application of algothmic calculations of the equipment characteristics using the information accumulated during the system development, erection and operation is described

  18. Levels of medical support for United Nations peacekeeping operations. (United States)

    Seet, B


    It is important to standardize the classification of medical units in United Nations (U.N.) peacekeeping operations to ensure that they meet operational requirements and to facilitate planning and administration. It further ensures interoperability between medical facilities from different countries. The U.N. Department of Peacekeeping Operations has adopted a four-level medical support organization, with the classification level of a unit largely determined by its treatment capability and capacity. Planning and allocation of medical resources depend largely on the peacekeeping mandate, the type of peacekeeping operation, existing medical infrastructure, geographical factors, and assessed medical threats. A summary of medical units currently deployed in U.N. peacekeeping missions is presented. This should promote understanding of the U.N. medical support concept and assist national military organizations in the planning for such operations.

  19. Biotechnology's foreign policy. (United States)

    Feldbaum, Carl


    From its inception, biotechnology has been a uniquely international enterprise. An American and an Englishman working together elucidated the structure of DNA almost 50 years ago; more recently, the Human Genome Project linked researchers around the world, from the Baylor College of Medicine in Houston to the Beijing Human Genome Center. Today our industry's researchers hail from African villages and Manhattan high rises; from Munich and Melbourne; from London, Ontario, and London, England; from Scotland and Nova Scotia--New Scotland; from Calcutta and Calgary. But in the beginning, the infrastructure that supported these efforts--intellectual property, venture capital, streamlined technology transfer--was less widely dispersed and the world's brightest biotech researchers clustered in only half a dozen scientific Meccas. Previous technological revolutions have spread around the world. Following in their footsteps, biotechnology's global diaspora seems inevitable, especially since governments are promoting it. But as our science and business emigrate from early strongholds in the United States, Canada and Europe across oceans and borders and into new cultures, international tensions over biotechnology continue to grow. In just the last few years, controversies have rolled over R&D spending priorities, genetic patents, bioprospecting, transgenic agriculture and drug pricing. My premise today is that our industry needs to formulate its first foreign policy, one which is cognizant of the miserable judgments and mistakes of other industries--and avoids them.

  20. A framework for operator support systems for CANDU

    International Nuclear Information System (INIS)

    Lupton, L.R.; Lipsett, J.J.; Shah, R.R.


    The size and complexity of nuclear power plants has increased significantly in the last 20 years. There is a general agreement that both plant safety and availability can be enhanced by providing the operator with more operational support if that can be cone without overloading him/her with unnecessary information. Recent advances in computer technology provide opportunities for implementing operator support systems that are significantly different from the ones based on the more conventional technologies used in plant control rooms. In particular, artificial intelligence (AI) and the related technologies will play a major role in the development of innovative methods for information processing and presentation. Our approach to these technologies is that they must be integrated into the overall management and control philosophy of the plant and are not to be treated as vehicles to implement point solutions. The underlying philosophy behind this approach and the design objectives and goals for the CANDU 3 control centre are discussed in this paper. Operator support systems will integrate into the overall controll philosophy by complementing the operator. There is also a role for such systems in assisting the operator be a 'situation manager' organizing, managing and planning the running of the plant. Four support systems that invorporate the underlying philosophy are described

  1. A framework for operator support systems for CANDU

    International Nuclear Information System (INIS)

    Lupton, L.R.; Lipsett, J.J.; Shah, R.R.


    The size and complexity of nuclear power plants has increased significantly in the last 20 years. There is a general agreement that both plant safety and availability can be enhanced by providing the operator with more operational support if than can be done without overloading him/her with unnecessary information. Recent advances in computer technology provide opportunities for implementing operator support systems that are significantly different from the ones based on the more conventional technologies used in plant control rooms. In particular, artificial intelligence and the related technologies will play a major role in the development of innovative methods for information processing and presentation. Our approach to these technologies is that they must be integrated into the overall management and control philosophy of the plant and are not to be treated as vehicles to implement point solutions. The underlying philosophy behind this approach and the design objectives and goals for the CANDU 3 control centre are discussed in this paper. Operator support systems will integrate into the overall control philosophy by complementing the operator. There is also a role for such systems in assisting the operator to be a situation manager, organizing, managing and planning the running of the plant. Four support systems that incorporate the underlying philosophy are described

  2. Computerized Operator Support System – Phase II Development

    Energy Technology Data Exchange (ETDEWEB)

    Ulrich, Thomas A.; Boring, Ronald L.; Lew, Roger T.; Thomas, Kenneth D.


    A computerized operator support system (COSS) prototype for nuclear control room process control is proposed and discussed. The COSS aids operators in addressing rapid plant upsets that would otherwise result in the shutdown of the power plant and interrupt electrical power generation, representing significant costs to the owning utility. In its current stage of development the prototype demonstrates four advanced functions operators can use to more efficiently monitor and control the plant. These advanced functions consist of: (1) a synthesized and intuitive high level overview display of system components and interrelations, (2) an enthalpy-based mathematical chemical and volume control system (CVCS) model to detect and diagnose component failures, (3) recommended strategies to mitigate component failure effects and return the plant back to pre-fault status, and (4) computer-based procedures to walk the operator through the recommended mitigation actions. The COSS was demonstrated to a group of operators and their feedback was collected. The operators responded positively to the COSS capabilities and features and indicated the system would be an effective operator aid. The operators also suggested several additional features and capabilities for the next iteration of development. Future versions of the COSS prototype will include additional plant systems, flexible computer-based procedure presentation formats, and support for simultaneous component fault diagnosis and dual fault synergistic mitigation action strategies to more efficiently arrest any plant upsets.

  3. Control, Operator Support and Safety System of PVC-reactors

    Directory of Open Access Journals (Sweden)

    Jens I. Ytreeide


    Full Text Available In modern petrochemical plants the corporate and societal demands to plant safety and minimum environmental effects are high. These demands rise high performance requirements to the technical systems, specially the process control and safety systems including an effective operator support system with fault detection capability. The systems must have high reliability also against erroneous operations which may cause shutdown situations or quality deviations.

  4. Artificial intelligence program in a computer application supporting reactor operations

    International Nuclear Information System (INIS)

    Stratton, R.C.; Town, G.G.


    Improving nuclear reactor power plant operability is an ever-present concern for the nuclear industry. The definition of plant operability involves a complex interaction of the ideas of reliability, safety, and efficiency. This paper presents observations concerning the issues involved and the benefits derived from the implementation of a computer application which combines traditional computer applications with artificial intelligence (AI) methodologies. A system, the Component Configuration Control System (CCCS), is being installed to support nuclear reactor operations at the Experimental Breeder Reactor II

  5. Spatial Diversity of Biotechnology Centres in Germany

    Directory of Open Access Journals (Sweden)

    Dorocki Sławomir


    Full Text Available Biotechnology is considered one of the key advanced technology sectors of the future. Its development is conditional on basic research in technologically advanced research institutes and appropriately qualified human resources. The optimum environment stimulating the development of biotechnology is that of production centres having joint industrial and R&D operations.

  6. A Framework to Support the Fusion of Operation and Planning

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Yousu; Etingov, Pavel V.; Fitzhenry, Erin B.; Sharma, Poorva; Nguyen, Tony B.; Makarov, Yuri V.; Rice, Mark J.; Allwardt, Craig H.; Widergren, Steven E.


    The management of the nation’s power system has progressed to the point where the boundary lines between operations and planning are becoming blurred. The dynamic behavior of smart grid technologies brings pressures of incorporating the predictive capability from planning to enhance operations. These needs are requiring a smoother, better integrated interplay between the functional roles of planning and operations. This paper presents a framework to support the fusion of operation and planning. A case study of predicting the intra-hour deficiency in generation capability and ramping capacity and presenting the outputs to operators was conducted. The study shows the benefits of the fusion and the effectiveness of the framework. All the function blocks used in the study were built upon GridOPTICS Software System (GOSS), a software system middleware platform that facilitates deployment of new applications for the future power grid.

  7. Simulating Sustainment for an Unmanned Logistics System Concept of Operation in Support of Distributed Operations (United States)


    SUSTAINMENT FOR AN UNMANNED LOGISTICS SYSTEM CONCEPT OF OPERATION IN SUPPORT OF DISTRIBUTED OPERATIONS by Elle M. Ekman June 2017 Thesis...REPORT DATE June 2017 3. REPORT TYPE AND DATES COVERED Master’s thesis 4. TITLE AND SUBTITLE SIMULATING SUSTAINMENT FOR AN UNMANNED LOGISTICS SYSTEM... logistics always seeks to remain responsive, flexible, and sustainable to successfully support highly maneuverable units dispersed over large

  8. Research on operation support system for nuclear power plants

    International Nuclear Information System (INIS)

    Wakabayashi, Jiro


    Nuclear power plants are the typical, complex, large scale engineering system, and at the time of accidents, there is the possibility to extend disasters to wide range beyond borders, therefore, it is the feature that the requirement for their reliability and safety is much severe as compared with other engineering systems. The fact that human errors become the major cause of large accidents is in common in large scale engineering systems, and the development of the operation support system for preventing it has become an important research subject. Also the research on design support system and maintenance support system is in progress to prevent human errors. Operation support system is composed of diagnostic system, operation guide system, man-machine interface and knowledge data base, and throughout these, the research on the human errors arising in the process of human decision making becomes the basis. Rasmussen's model for decision making, the classification of human errors and the reliability analysis for men, the factors affecting human errors, the acquisition of knowledge, the compilation and management of knowledge data base, the diagnostic system, operation guide system and man-machine interface are described. (K.I.)

  9. Schrodinger operators with delta-interactions supported on conical surfaces

    Czech Academy of Sciences Publication Activity Database

    Behrndt, J.; Exner, Pavel; Lotoreichik, V.


    Roč. 47, č. 35 (2014), s. 355202 ISSN 1751-8113 R&D Projects: GA ČR(CZ) GA14-06818S; GA MŠk 7AMB13AT010 Institutional support: RVO:61389005 Keywords : Schrödinger operator * delta potential * infinite discrete spectrum Subject RIV: BE - Theoretical Physics Impact factor: 1.583, year: 2014

  10. Co-ordinating humanitarian operations in peace support missions

    NARCIS (Netherlands)

    Rietjens, S.J.H.; Voordijk, Johannes T.; de Boer, S.J.


    Purpose – This paper seeks to contribute to a more effective co-ordination of humanitarian operations by military and civilian organizations involved in a peace support mission in response to a complex emergency. Design/methodology/approach – The information processing view, in particular

  11. The South African Military and Peace Support Operations ...

    African Journals Online (AJOL)


    May 4, 1996 ... The South African Military and Peace Support. Operations: Responding to the Challenges and. Preparing for Engagement. DR T.G. NEETHLING. Centre for Military Studies, University of Stellenbosch. Suid-Afrika het in die afgelope tyd om meer as een rede toenemend by politiek- diplomatieke ...

  12. Task analysis and decision support requirements for Dynamic Positioning operators

    NARCIS (Netherlands)

    Hueting, T.F.; Rypkema, J.A.


    The present research was conducted as part of the Early Research Program Human Enhancement in the domain of Adaptive Maritime Automation, which strives to develop knowledge regarding the support of operators based on adaptively automated systems. To apply the developed knowledge about adaptive

  13. Integrated training support system for PWR operator training simulator

    International Nuclear Information System (INIS)

    Sakaguchi, Junichi; Komatsu, Yasuki


    The importance of operator training using operator training simulator has been recognized intensively. Since 1986, we have been developing and providing many PWR simulators in Japan. We also have developed some training support systems connected with the simulator and the integrated training support system to improve training effect and to reduce instructor's workload. This paper describes the concept and the effect of the integrated training support system and of the following sub-systems. We have PES (Performance Enhancement System) that evaluates training performance automatically by analyzing many plant parameters and operation data. It can reduce the deviation of training performance evaluation between instructors. PEL (Parameter and Event data Logging system), that is the subset of PES, has some data-logging functions. And we also have TPES (Team Performance Enhancement System) that is used aiming to improve trainees' ability for communication between operators. Trainee can have conversation with virtual trainees that TPES plays automatically. After that, TPES automatically display some advice to be improved. RVD (Reactor coolant system Visual Display) displays the distributed hydraulic-thermal condition of the reactor coolant system in real-time graphically. It can make trainees understand the inside plant condition in more detail. These sub-systems have been used in a training center and have contributed the improvement of operator training and have gained in popularity. (author)

  14. Support Operators Method for the Diffusion Equation in Multiple Materials

    Energy Technology Data Exchange (ETDEWEB)

    Winters, Andrew R. [Los Alamos National Laboratory; Shashkov, Mikhail J. [Los Alamos National Laboratory


    A second-order finite difference scheme for the solution of the diffusion equation on non-uniform meshes is implemented. The method allows the heat conductivity to be discontinuous. The algorithm is formulated on a one dimensional mesh and is derived using the support operators method. A key component of the derivation is that the discrete analog of the flux operator is constructed to be the negative adjoint of the discrete divergence, in an inner product that is a discrete analog of the continuum inner product. The resultant discrete operators in the fully discretized diffusion equation are symmetric and positive definite. The algorithm is generalized to operate on meshes with cells which have mixed material properties. A mechanism to recover intermediate temperature values in mixed cells using a limited linear reconstruction is introduced. The implementation of the algorithm is verified and the linear reconstruction mechanism is compared to previous results for obtaining new material temperatures.

  15. Telescience testbed: Operational support functions for biomedical experiments (United States)

    Yamashita, Masamichi; Watanabe, Satoru; Shoji, Takatoshi; Clarke, Andrew H.; Suzuki, Hiroyuki; Yanagihara, Dai

    A telescience testbed was conducted to study the methodology of space biomedicine with simulated constraints imposed on space experiments. An experimental subject selected for this testbedding was an elaborate surgery of animals and electrophysiological measurements conducted by an operator onboard. The standing potential in the ampulla of the pigeon's semicircular canal was measured during gravitational and caloric stimulation. A principal investigator, isolated from the operation site, participated in the experiment interactively by telecommunication links. Reliability analysis was applied to the whole layers of experimentation, including design of experimental objectives and operational procedures. Engineering and technological aspects of telescience are discussed in terms of reliability to assure quality of science. Feasibility of robotics was examined for supportive functions to reduce the workload of the onboard operator.

  16. Decision Support Systems for Launch and Range Operations Using Jess (United States)

    Thirumalainambi, Rajkumar


    The virtual test bed for launch and range operations developed at NASA Ames Research Center consists of various independent expert systems advising on weather effects, toxic gas dispersions and human health risk assessment during space-flight operations. An individual dedicated server supports each expert system and the master system gather information from the dedicated servers to support the launch decision-making process. Since the test bed is based on the web system, reducing network traffic and optimizing the knowledge base is critical to its success of real-time or near real-time operations. Jess, a fast rule engine and powerful scripting environment developed at Sandia National Laboratory has been adopted to build the expert systems providing robustness and scalability. Jess also supports XML representation of knowledge base with forward and backward chaining inference mechanism. Facts added - to working memory during run-time operations facilitates analyses of multiple scenarios. Knowledge base can be distributed with one inference engine performing the inference process. This paper discusses details of the knowledge base and inference engine using Jess for a launch and range virtual test bed.

  17. Biotechnology organizations in action

    DEFF Research Database (Denmark)

    Norus, Jesper

    This volume analyzes the dynamics and interactive processes among the players (individuals, institutions, and organizations/firms) that have constituted and legitimized the development of the biotechnology industries. The unit of analysis is small entrepreneurial firms developing biotechnological...

  18. Biotechnological applications of bacterial cellulases

    Czech Academy of Sciences Publication Activity Database

    Menéndez, E.; García-Fraile, Paula; Rivas, R.


    Roč. 2, č. 3 (2015), s. 163-182 ISSN 2306-5354 R&D Projects: GA MŠk(CZ) EE2.3.30.0003 Institutional support: RVO:61388971 Keywords : Biotechnological applications * Bacterial cellulases * Cellulose degradation Subject RIV: EE - Microbiology, Virology

  19. Patenting Biotechnological Inventions in Europe

    Directory of Open Access Journals (Sweden)

    Peter Raspor


    Full Text Available The patent system has been able to provide the protection for the achievements of different technologies and in that way it has supported further development and growth of the industry where those achievements were implemented. Modern technologies like information technology and biotechnology with genetic engineering that appeared in the 70s have overgrown the frames of the existing patent system because of their exponential development during the last thirty years. Industry that invests a huge amount of money in these technologies, especially in the field of biotechnology, where the results are very uncertain, has started to claim changes in the patent system.

  20. Cross support overview and operations concept for future space missions (United States)

    Stallings, William; Kaufeler, Jean-Francois


    Ground networks must respond to the requirements of future missions, which include smaller sizes, tighter budgets, increased numbers, and shorter development schedules. The Consultative Committee for Space Data Systems (CCSDS) is meeting these challenges by developing a general cross support concept, reference model, and service specifications for Space Link Extension services for space missions involving cross support among Space Agencies. This paper identifies and bounds the problem, describes the need to extend Space Link services, gives an overview of the operations concept, and introduces complimentary CCSDS work on standardizing Space Link Extension services.

  1. Argentina's operator support systems in nuclear power plants

    International Nuclear Information System (INIS)

    Goldstein, M.; Palamidessi, H.


    The development of operator support systems for nuclear power plants started in Argentina a few years ago. Four systems are at present deployed or under development. The participation of utility personnel in the co-ordinated research program has helped in revising the current experience and in selecting and specifying the systems to be developed and the resources needed for their implementation. Main efforts will be aimed to the selection of those systems that can be more easily implemented, to improve the data retrieval and handling, to develop diverse supplies of software products and to promote the understanding of support systems among the potential end users. (author). 12 refs

  2. Instrumentation and control activities at the Electric Power Research Institute to support operator support systems

    International Nuclear Information System (INIS)

    Naser, J.


    Most nuclear power plants in the United States continue to operate with analog instrumentation and control (I and C) technology designed 20 to 40 years ago. This equipment is approaching or exceeding its life expectancy, resulting in increasing maintenance efforts to sustain system performance. Decreasing availability of replacement parts and the accelerating deterioration of the infrastructure of manufacturers that support analog technology exacerbate obsolescence problems and resultant operation and maintenance (O and M) cost increases. Modern digital technology holds a significant potential to improve the safety, cost-effectiveness, productivity, and, therefore, competitiveness of nuclear power plants. Operator support systems provide the tools to help achieve this potential. Reliable, integrated information is a critical element for protecting the utility's capital investment and increasing availability, reliability, and productivity. Integrated operator support systems with integrated information can perform more effectively to increase productivity, to enhance safety, and to reduce O and M costs. The plant communications and computing architecture is the infrastructure needed to allow the implementation of I and C systems and associated operator support systems in an integrated manner. Current technology for distributed digital systems, plant process computers, and plant communications and computing networks support the integration of systems and information. (author). 16 refs

  3. A Study on the Operator Decision Support for Feed-and-Bleed Operation

    International Nuclear Information System (INIS)

    Kim, Bo Gyung; Kim, Sang Ho; Kang, Hyun Gook; Yoon, Ho Joon


    In the case of a combined accident that includes a failure of the secondary cooling system, it is difficult for operators to recognize the necessity of an feed and bleed (F and B) operation because a lot of parameters and alarms should be checked before a decision, and operators may spend a considerable amount of time arriving at the entry for a proper emergency operating procedure that contains the procedure for an F and B operation. Therefore, a clear identification of the success boundary of an F and B operation would help operators in their decision-making when a combined accident that includes a secondary cooling system failure occurs. This study will provide a useful guideline for the initiation of an F and B operation for operators. Cooling the RCS after a scram is one of the most important safety functions for preventing core damage. To support the operator in decision making whether to initiate the F and B operation, plant conditions requiring the initiation of an F and B operation were identified. Plant conditions are affected by the steam generator inventory, RCS inventory, core inventory, and safety injection availability. The combination of accident types, component availabilities, and the initiation time of an F and B operation affect the success of the F and B operation. Operators need clear information about the RCS condition when the steam generators, the RCS's main residual heat removal mechanism, become unavailable. When this happens, the initiation of an F and B operation becomes necessary. As the number of the state increases, the necessity of an F and B operation increases. Especially, the operator should initiate an F and B operation when the RCS condition enters State 3 for Type 1 incidents or State 3-2 for Type 2 incidents. The results of this study may be useful in providing information regarding the necessity and effects of an F and B operation in a quantitative manner. In particular, in the case of a combined accident including a

  4. Study on supporting system for operator's comprehensive understanding

    International Nuclear Information System (INIS)

    Yoshikawa, Shinji


    Power Reactor and Nuclear Fuel Development Corp. has participated in the development of a system to support the process of operator's plant understanding by the use of information processing techniques such as artificial intelligence since 1994. Analysis and model formation of the process leading to operator's comprehensive understanding of plant (mental model) are undertaken attempting to determine the basic structure of the mental model available for the description of knowledge using the precedent survey and to observe how to utilize operator's own knowledge. After consideration of the way by which plant operators utilize their physical knowledges and the knowledges of physical observation in practice, a basic structure composed of 3 components a qualitative causal network, a hierarchical function model and 3 links joining the two was proposed for the mental model. A questionnaire survey on operator's statements was made and the contents were assigned in several categories for objective analysis. An unified form usable to make a data base was established. Further, we have a plan to develop the first proto-type system to promote operator's understanding by 1998. (M.N.)

  5. Use of safety analysis results to support process operation

    International Nuclear Information System (INIS)

    Karvonen, I.; Heino, P.


    Safety and risk analysis carried out during the design phase of a process plant produces useful knowledge about the behavior and the disturbances of the system. This knowledge, however, often remains to the designer though it would be of benefit to the operators and supervisors of the process plant, too. In Technical Research Centre of Finland a project has been started to plan and construct a prototype of an information system to make use of the analysis knowledge during the operation phase. The project belongs to a Nordic KRM project (Knowledge Based Risk Management System). The information system is planned to base on safety and risk analysis carried out during the design phase and completed with operational experience. The safety analysis includes knowledge about potential disturbances, their causes and consequences in the form of Hazard and Operability Study, faut trees and/or event trees. During the operation disturbances can however, occur, which are not included in the safety analysis, or the causes or consequences of which have been incompletely identified. Thus the information system must also have an interface for the documentation of the operational knowledge missing from the analysis results. The main tasks off the system when supporting the management of a disturbance are to identify it (or the most important of the coexistent ones) from the stored knowledge and to present it in a proper form (for example as a deviation graph). The information system may also be used to transfer knowledge from one shift to another and to train process personnel

  6. Decision Support Functions for the Retail Operations Management System. (United States)


    compatible microcomputer, that would deny the benefit of these decision support functions to the fleet for years. The ROM System enhancements were designed... denied access to the Stock Record Master Maintenance function (PF 1 on the ROM Master Menu). By pressing the ENTER key, the user will be returned to screen...message 222006Z NOV 93. 6. COMNAYSUPSYSCOM WASHINGTON DC. Retail Operations Management (ROM) Certification. Naval message 222146Z MAR 94. 7. Cosgrove

  7. Support system for loop device operator. Analysis of technological processes

    International Nuclear Information System (INIS)

    Yakovlev, V.V.; Mozhaev, A.A.; Lyadin, A.V.


    The paper presents the results obtained from the analysis of controlling the loops of a research reactor. A method of optimized interaction of the operator and hardware of the control system by computeraided identification of the cause of regime violation is considered. The equipment diagnostics based on use of the expert system methods and tuzzy algorithms enables to propose a support system for application in new generation of loops

  8. RTEMS Centre - Support and Maintenance Centre to RTEMS Operating System (United States)

    Silva, H.; Constantino, A.; Freitas, D.; Coutinho, M.; Faustino, S.; Mota, M.; Colaço, P.; Sousa, J.; Dias, L.; Damjanovic, B.; Zulianello, M.; Rufino, J.


    RTEMS CENTRE - Support and Maintenance Centre to RTEMS Operating System is a joint ESA/Portuguese Task Force initiative to develop a support and maintenance centre to the Real-Time Executive for Multiprocessor Systems (RTEMS). This paper gives a high level visibility of the progress, the results obtained and the future work in the RTEMS CENTRE [6] and in the RTEMS Improvement [7] projects. RTEMS CENTRE started officially in November 2006, with the RTEMS version. A full analysis of RTEMS operating system was produced. The architecture was analysed in terms of conceptual, organizational and operational concepts. The original objectives [1] of the centre were primarily to create and maintain technical expertise and competences in this RTOS, to develop a website to provide the European Space Community an entry point for obtaining support (, to design, develop, maintain and integrate some RTEMS support tools (Timeline Tool, Configuration and Management Tools), to maintain flight libraries and Board Support Packages, to develop a strong relationship with the World RTEMS Community and finally to produce some considerations in ARINC-653, DO-178B and ECSS E-40 standards. RTEMS Improvement is the continuation of the RTEMS CENTRE. Currently the RTEMS, version 4.8.0, is being facilitated for a future qualification. In this work, the validation material is being produced following the Galileo Software Standards Development Assurance Level B [5]. RTEMS is being completely tested, errors analysed, dead and deactivated code removed and tests produced to achieve 100% statement and decision coverage of source code [2]. The SW to exploit the LEON Memory Management Unit (MMU) hardware will be also added. A brief description of the expected implementations will be given.

  9. The design of intelligent support systems for nuclear reactor operators

    International Nuclear Information System (INIS)

    Bernard, J.A.


    This paper identifies factors relevant to the design of intelligent support systems and their use for the provision of real-time diagnostic information. As such, it constitutes a followup to the state-of-the-art review that was previously published by Bernard and Washio on the utilization of expert systems within the nuclear industry. Some major differences between intelligent-support tools and conventional expert systems are enumerated. In summary, conventional expert systems that encode experimental knowledge in production rules are not suitable vehicle for the creation of operator support systems. The principal difficulty is the need for real-time operation. This in turn means that intelligent support systems will have knowledge bases derived from temporally accurate plant models, inference engines that permit revisions in the search process to accommodate revised data, and man-machine interfaces that do not require any human input. Such systems will be heavily instrumented, and the associated knowledge bases will require a hierarchical organization to emulate human approaches to analysis

  10. Aquatic modules for bioregenerative life support systems based on the C.E.B.A.S. biotechnology (United States)

    Bluem, Volker; Paris, Frank


    Most concepts for bioregenerative life support systems are based on edible higher land plants which create some problems with growth and seed generation under space conditions. Animal protein production is mostly neglected because of the tremendous waste management problems with tetrapods under reduced weightlessness. Therefore, the "Closed Equilibrated Biological Aquatic System" (C.E.B.A.S.) was developed which represents an artificial aquatic ecosystem containing aquatic organisms which are adpated at all to "near weightlessness conditions" (fishes Xiphophorus helleri, water snails Biomphalaria glabrata, ammonia oxidizing bacteria and the rootless non-gravitropic edible water plant Ceratophyllum demersum). Basically the C.E.B.A.S. consists of 4 subsystems: a ZOOLOGICASL COMPONENT (animal aquarium), a BOTANICAL COMPONENT (aquatic plant bioreactor), a MICROBIAL COMPONENT (bacteria filter) and an ELECTRONICAL COMPONENT (data acquisition and control unit). Superficially, the function principle appears simple: the plants convert light energy into chemical energy via photosynthesis thus producing biomass and oxygen. The animals and microorganisms use the oxygen for respiration and produce the carbon dioxide which is essential for plant photosynthesis. The ammonia ions excreted by the animals are converted by the bacteria to nitrite and then to nitrate ions which serve as a nitrogen source for the plants. Other essential ions derive from biological degradation of animal waste products and dead organic matter. The C.E.B.A.S. exists in 2 basic versions: the original C.E.B.A.S. with a volume of 150 liters and a self-sustaining standing time of more than 13 month and the so-called C.E.B.A.S. MINI MODULE with a volume of about 8.5 liters. In the latter there is no closed food loop by reasons of available space so that animal food has to be provided via an automated feeder. This device was flown already successfully on the STS-89 and STS-90 spaceshuttle missions and the

  11. The effects of Operation Rescue on pro-life support. (United States)

    Ansuini, C G; Fiddler-woite, J; Woitaszek, R S


    Operation Rescue is a militant anti-abortion group. The organization conveys its position against abortion by targeting a city in which it will mount speeches, rallies, pickets, and media barrages. Operation Rescue held activities in Greater Buffalo, New York, in 1992. The authors investigated the effect of the anti-abortion campaign upon a sample of non-activist university undergraduate students and the anti-abortion cause in general. 114 male and 195 female students of the State University of New York College at Buffalo participated. 60% were younger than age 22 years and 17% were 46 years of age or older. 87% were sexually active, but only 18% were married. 11% reported having an abortion themselves or dating someone who had. 150 subjects were surveyed each spring for three years with regard to their abortion-related attitudes and behaviors. 18% of the participants identified themselves as pro-life in 1991, 22% in 1992, and 12% in 1993, the year after the Operation Rescue campaign. 70% identified themselves as pro-choice in 1991, 60% in 1992, and 57% in 1993. The percentage of respondents reporting that they would not have an abortion themselves, but support a woman's right to free choice with regard to abortion steadily increased from 11% in 1991 to 19% in 1992 and 30% in 1993. In general, support for the anti-abortion camp increased during protest activities, but decreased overall over the long term. The campaign had a particularly negative effect upon males.

  12. Making Risk Models Operational for Situational Awareness and Decision Support

    Energy Technology Data Exchange (ETDEWEB)

    Paulson, Patrick R.; Coles, Garill A.; Shoemaker, Steven V.


    Modernization of nuclear power operations control systems, in particular the move to digital control systems, creates an opportunity to modernize existing legacy infrastructure and extend plant life. We describe here decision support tools that allow the assessment of different facets of risk and support the optimization of available resources to reduce risk as plants are upgraded and maintained. This methodology could become an integrated part of the design review process and a part of the operations management systems. The methodology can be applied to the design of new reactors such as small nuclear reactors (SMR), and be helpful in assessing the risks of different configurations of the reactors. Our tool provides a low cost evaluation of alternative configurations and provides an expanded safety analysis by considering scenarios while early in the implementation cycle where cost impacts can be minimized. The effects of failures can be modeled and thoroughly vetted to understand their potential impact on risk. The process and tools presented here allow for an integrated assessment of risk by supporting traditional defense in depth approaches while taking into consideration the insertion of new digital instrument and control systems.

  13. Portable Operating Systems for Network Computers: Distributed Operating Systems Support for Group Communications. (United States)


    Modula-2 MICROS/ MICRONET " (5) William S. Holmes, May 1983, "Version and Source Code Support Environment" (6) Michael J. Palumbo. May 1983, "Stand...Dist. Comp. Sys., Denver, CO, May 1985, 386- 393. 7. A. van Tilborg and L. D. Wittie, "Operating Systems for the Micronet Network Computer", IEEE Micro

  14. Pre-operative nutrition support in patients undergoing gastrointestinal surgery. (United States)

    Burden, Sorrel; Todd, Chris; Hill, James; Lal, Simon


    Post-operative management in gastrointestinal (GI) surgery is becoming well established with 'Enhanced Recovery After Surgery' protocols starting 24 hours prior to surgery with carbohydrate loading and early oral or enteral feeding given to patients the first day following surgery. However, whether or not nutritional intervention should be initiated earlier in the preoperative period remains unclear. Poor pre-operative nutritional status has been linked consistently to an increase in post-operative complications and poorer surgical outcome. To review the literature on preoperative nutritional support in patients undergoing gastrointestinal surgery (GI). The searches were initially run in March 2011 and subsequently updated in February 2012. Databases including all EBM Reviews (Cochrane DSR, ACP Journal Club, DARE, CCTR, CMR, HTA and NHSEED) MEDLINE, EMBASE, AMED, British Nursing Index Archive using OvidSP were included and a search was run on each database separately after which duplicates were excluded. The inclusion criteria were randomised controlled trials that evaluated pre-operative nutritional support in GI surgical participants using a nutritional formula delivered by a parenteral, enteral or oral route. The primary outcomes included post-operative complications and length of hospital stay. Two observers screened the abstracts for inclusion in the review and performed data extraction. Bias was assessed for each of the included studies using the bias assessment tables in the Cochrane Software Review Manager (version 5.1, Cochrane Collaboration). The trials were analysed using risk ratios with Mantel-Haenszel in fixed effects methods displayed with heterogeneity. Meta-analyses were undertaken on trials evaluating immune enhancing (IE) nutrition, standard oral supplements, enteral and parenteral nutrition (PN) which were administered pre-operatively.Study characteristics were summarised in tables. Dichotomous and ratio data were entered into meta-analyses for

  15. JOYO operation support system 'JOYCAT' based on intelligent alarm handling

    International Nuclear Information System (INIS)

    Tamaoki, Tetsuo; Yamamoto, Hiroki; Sato, Masuo; Yoshida, Megumu; Kaneko, Tomoko; Terunuma, Seiichi; Takatsuto, Hiroshi; Morimoto, Makoto.


    An operation support system for the experimental fast reactor 'JOYO' was developed based on an intelligent alarm-handling. A specific feature of this system, called JOYCAT (JOYO Consulting and Analyzing Tool), is in its sequential processing structure that a uniform treatment by using design knowledge base is firstly applied for all activated alarms, and an exceptional treatment by using heuristic knowledge base is then applied only for the former results. This enables us to achieve real-time and flexible alarm-handling. The first alarm-handling determines the candidates of causal alarms, important alarms with which the operator should firstly cope, through identifying the cause-consequence relations among alarms based on the design knowledge base in which importance and activating conditions are described for each of 640 alarms in a frame format. The second alarm-handling makes the final judgement with the candidates by using the heuristic knowledge base described as production rules. Then, operation manuals concerning the most important alarms are displayed to operators. JOYCAT has been in commission since September of 1990, after a wide scope of validation tests by using an on-site full-scope training simulator. (author)

  16. The Initial Development of a Computerized Operator Support System

    Energy Technology Data Exchange (ETDEWEB)

    Roger Lew; Ronald L Boring; Thomas A Ulrich; Ken Thomas


    A computerized operator support system (COSS) is a collection of resilient software technologies to assist operators in monitoring overall nuclear power plant performance and making timely, informed decisions on appropriate control actions for the projected plant condition. The COSS provides rapid assessments, computations, and recommendations to reduce workload and augment operator judgment and decision-making during fast- moving, complex events. A prototype COSS for a chemical volume control system at a nuclear power plant has been developed in order to demonstrate the concept and provide a test bed for further research. The development process identified four underlying elements necessary for the prototype, which consist of a digital alarm system, computer-based procedures, piping and instrumentation diagram system representations, and a recommender module for mitigation actions. An operational prototype resides at the Idaho National Laboratory (INL) using the U.S. Department of Energy’s (DOE) Light Water Reactor Sustainability (LWRS) Human Systems Simulation Laboratory (HSSL). Several human-machine interface (HMI) considerations are identified and incorporated in the prototype during this initial round of development.

  17. Licensing Support Experience of the BN-600 Operation

    International Nuclear Information System (INIS)

    Khrennikov, N.; Sintsov, A.


    License procedure - Main principle: • All works, including fatigue tests of new types of fuel, are carried out at the unit 3 Beloyarsk nuclear power plants with the BN-600 reactor with the justification of the regulatory body. • Justification procedure is standard for all power units and independent from the reactor types. • The regulatory body and independent experts or technical support organizations, which can be involved in this work by the regulatory body, review SAR, operational manuals and other operator documents. • Safety requirements (i.e. Federal rules and codes). The project and design documents shall meet safety requirements. • The technical and organizational measures for safety guarantee shall meet well-known results of the research investigations or shall be experimental validate

  18. Design and operation of the emergency support center, CAE

    International Nuclear Information System (INIS)

    Caro, R. J.; Lopez Trillo, E.


    The enhancements developed in Spain in the area of Emergency Management, as consequence of the accident at the Fukushima Dai-Ichi NPP in 2011, included the definition of new emergency response centers; Alternative Center for Emergency Management (CAGE) on each NPP and the Emergency Support Center (CAE), shared by all NPPs. This article summarizes the main features and operation activities undertaken since the establishment of the new CAE, centralized, external to the NPPs shared by all Spanish plants and managed by Tecnatom. (Author)

  19. Decision support for simulation-based operation planning (United States)

    Schubert, Johan; Hörling, Pontus


    In this paper, we develop methods for analyzing large amounts of data from a military ground combat simulation system. Through a series of processes, we focus the big data set on situations that correspond to important questions and show advantageous outcomes. The result is a decision support methodology that provides commanders with results that answer specific questions of interest, such as what the consequences for the Blue side are in various Red scenarios or what a particular Blue force can withstand. This approach is a step toward taking the traditional data farming methodology from its analytical view into a prescriptive operation planning context and a decision making mode.

  20. Total connectivity speeds research and support of field operations

    International Nuclear Information System (INIS)

    Himes, R.E.; Frost, K.I.; Henry, S.R.; Funkhouser, J.D.


    This paper reports that research and field support roles in the oilfield service industry have become increasingly complex in the last 15 years. Experimental apparatus are more dependent on the data-acquisition and processing capabilities of computers as the amount of data generated increases. Therefore, the need to network these computers for data transport has significantly increased. The type of network system selected depends on the goals to be achieved. Incorporation of existing equipment, communication between systems of different architectures, and future expandability are only a few of the necessary attributes. With these in mind, a computer network system was designed and is being implemented. The system combines local- and wide-area networks (LAN's or WAN's) of different protocols to acquire, process, and transport information worldwide. The result is faster development of new products and quicker response in support of field operations

  1. Development of NPP Monitoring and Operation Support Technology

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jung Woon; Park, Jae Chang; Lee, Yong Hee [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)] (and others)


    During the first stage (2001.7.1-2004.6.30), we developed general human factors design guidelines VDU-based workstations, PMAS alarm display design guidelines, PMAS SPADES display design guidelines, and the revision of KHNP HFE guidelines (HF-010), which have been applied to domestic NPP designs. We also supported other KNICS projects by performing RPS COM design reviews, development of RPS COM Style Guide, and a review of CEDMCS cabinet operator module display design. We developed the ADIOS prototype, NPP performance analysis systems for YGN No.1, 2 plants and Kori No. 2 plant, alarm cause tracking systems for Kori No. 2 plant and OPR1000, and signal fault detection and diagnosis methods for deaerators and steam generators. During the second stage(2004.7.1-2008.4.30), we supported other KNICS projects by reviewing RPS COM display designs three times, developing ESF-CCS COM style guides and reviewing ESF-CCS COM display design, reviewing CRCS LOM and PCS MTP display designs, and developing requirements for DCS GUI components. We also developed integrated style guide for I and C cabinet operator module display designs. In cooperative research with KOPEC-AE, we developed basic technologies for advanced HSI design including task analysis methods, an information and control requirements database, display design criteria, a HSI prototype with its evaluation, and methods for human factors engineering verification and validation.

  2. Computer based aids for operator support in nuclear power plants

    International Nuclear Information System (INIS)


    In the framework of the Agency's programme on nuclear safety a survey was carried out based on a questionnaire to collect information on computer based aids for operator support in nuclear power plants in Member States. The intention was to put together a state-of-the-art report where different systems under development or already implemented would be described. This activity was also supported by an INSAG (International Nuclear Safety Advisory Group) recommendation. Two consultant's meetings were convened and their work is reflected in the two sections of the technical document. The first section, produced during the first meeting, is devoted to provide some general background material on the overall usability of Computerized Operator Decision Aids (CODAs), their advantages and shortcomings. During this first meeting, the first draft of the questionnaire was also produced. The second section presents the evaluation of the 40 questionnaires received from 11 Member States and comprises a short description of each system and some statistical and comparative observations. The ultimate goal of this activity was to inform Member States, particularly those who are considering implementation of a CODA, on the status of related developments elsewhere. 8 refs, 10 figs, 4 tabs

  3. Radiological Operations Support Specialist (ROSS) Pilot Course Summary and Recommendations

    Energy Technology Data Exchange (ETDEWEB)

    Alai, M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Askin, A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Buddemeier, B. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wogan, L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Doshi, P. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Tai, L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)


    In support of the Department of Homeland Security / Science and Technology Directorate’s (DHS/S&T) creation of a new position called the Radiological Operations Support Specialist (ROSS), Lawrence Livermore National Laboratory (LLNL) in Sub-task 1.1 and 1.2 has assisted in the development of the ROSS skills, knowledge, and abilities (SKAs); identified potentially relevant training; cross-mapped the training to the SKAs; and identified gaps in the training related to the SKAs, as well as their respective level of training knowledge - current versus desired. In the follow on task, Sub-task 1.3, a 5 day ROSS Pilot Training course was developed to fill the priority gaps identified in Sub-Task 1.2. Additionally, in Sub-Task 1.5, LLNL has performed a gap analysis of electronic tools, handbooks, and job-aides currently available to the ROSS and developed recommendations for additional and next generation tools to ensure the operational effectiveness of the ROSS position. This document summarizes the feedback received from the instructors and pilot course observers on what worked in the course and what could be improved as well as an assessment of the Pre- and Post-Test administered to the students.

  4. Development of NPP Monitoring and Operation Support Technology

    International Nuclear Information System (INIS)

    Lee, Jung Woon; Park, Jae Chang; Lee, Yong Hee


    During the first stage (2001.7.1-2004.6.30), we developed general human factors design guidelines VDU-based workstations, PMAS alarm display design guidelines, PMAS SPADES display design guidelines, and the revision of KHNP HFE guidelines (HF-010), which have been applied to domestic NPP designs. We also supported other KNICS projects by performing RPS COM design reviews, development of RPS COM Style Guide, and a review of CEDMCS cabinet operator module display design. We developed the ADIOS prototype, NPP performance analysis systems for YGN No.1, 2 plants and Kori No. 2 plant, alarm cause tracking systems for Kori No. 2 plant and OPR1000, and signal fault detection and diagnosis methods for deaerators and steam generators. During the second stage(2004.7.1-2008.4.30), we supported other KNICS projects by reviewing RPS COM display designs three times, developing ESF-CCS COM style guides and reviewing ESF-CCS COM display design, reviewing CRCS LOM and PCS MTP display designs, and developing requirements for DCS GUI components. We also developed integrated style guide for I and C cabinet operator module display designs. In cooperative research with KOPEC-AE, we developed basic technologies for advanced HSI design including task analysis methods, an information and control requirements database, display design criteria, a HSI prototype with its evaluation, and methods for human factors engineering verification and validation

  5. Ensemble Streamflow Forecast Improvements in NYC's Operations Support Tool (United States)

    Wang, L.; Weiss, W. J.; Porter, J.; Schaake, J. C.; Day, G. N.; Sheer, D. P.


    Like most other water supply utilities, New York City's Department of Environmental Protection (DEP) has operational challenges associated with drought and wet weather events. During drought conditions, DEP must maintain water supply reliability to 9 million customers as well as meet environmental release requirements downstream of its reservoirs. During and after wet weather events, DEP must maintain turbidity compliance in its unfiltered Catskill and Delaware reservoir systems and minimize spills to mitigate downstream flooding. Proactive reservoir management - such as release restrictions to prepare for a drought or preventative drawdown in advance of a large storm - can alleviate negative impacts associated with extreme events. It is important for water managers to understand the risks associated with proactive operations so unintended consequences such as endangering water supply reliability with excessive drawdown prior to a storm event are minimized. Probabilistic hydrologic forecasts are a critical tool in quantifying these risks and allow water managers to make more informed operational decisions. DEP has recently completed development of an Operations Support Tool (OST) that integrates ensemble streamflow forecasts, real-time observations, and a reservoir system operations model into a user-friendly graphical interface that allows its water managers to take robust and defensible proactive measures in the face of challenging system conditions. Since initial development of OST was first presented at the 2011 AGU Fall Meeting, significant improvements have been made to the forecast system. First, the monthly AR1 forecasts ('Hirsch method') were upgraded with a generalized linear model (GLM) utilizing historical daily correlations ('Extended Hirsch method' or 'eHirsch'). The development of eHirsch forecasts improved predictive skill over the Hirsch method in the first week to a month from the forecast date and produced more realistic hydrographs on the tail

  6. Decision Support System for Reservoir Management and Operation in Africa (United States)

    Navar, D. A.


    Africa is currently experiencing a surge in dam construction for flood control, water supply and hydropower production, but ineffective reservoir management has caused problems in the region, such as water shortages, flooding and loss of potential hydropower generation. Our research aims to remedy ineffective reservoir management by developing a novel Decision Support System(DSS) to equip water managers with a technical planning tool based on the state of the art in hydrological sciences. The DSS incorporates a climate forecast model, a hydraulic model of the watershed, and an optimization model to effectively plan for the operation of a system of cascade large-scale reservoirs for hydropower production, while treating water supply and flood control as constraints. Our team will use the newly constructed hydropower plants in the Omo Gibe basin of Ethiopia as the test case. Using the basic HIDROTERM software developed in Brazil, the General Algebraic Modeling System (GAMS) utilizes a combination of linear programing (LP) and non-linear programming (NLP) in conjunction with real time hydrologic and energy demand data to optimize the monthly and daily operations of the reservoir system. We compare the DSS model results with the current reservoir operating policy used by the water managers of that region. We also hope the DSS will eliminate the current dangers associated with the mismanagement of large scale water resources projects in Africa.

  7. CRISP. Dependable ICT Support of Power Grid Operations

    International Nuclear Information System (INIS)

    Gustavsson, R.; Mellstrand, P.; Tornqvist, B.; Akkermans, H.


    This deliverable D2.4 Dependable ICT support 0f Power Grid Operations is a link between deliverable D1.6 Information security models and their economics and planned activities in WP III, that is, Implementation, Experiments and Tests. Background CRISP material includes deliverables of D2.2 Design document and multi-agent simulation tool for distributed demand-supply matching and D2.3 Design document and simulation tool for diagnostics of high-DG power networks. Furthermore there are links between this document and the deliverable D1.7 Report on distributed network architectures and D1.8 Reports on case study simulations and results. In short, this document specifies and extends the general background on security models and dependability models of deliverable D1.6 with CRISP specific material of D2.2 and D2.4 towards the experiments and tests of WP III. The focus of this deliverable is on dependable ICT support of power grid operation. By recasting the three CRISP experiments into three Scenarios in Chapter 2 we claim that we have a good description of benefits and challenges related to future virtual utilities. Among the challenges are securing trustworthy operation from a technical operation side (avoid disturbances such as blackouts) as wee as from a user-centric business point of view (value added power related services). Our investigation on proper means to safeguard operations of future virtual utilities begins with an assessment of lessons learned from recent (2003) big blackouts worldwide in Chapter 3. We propose an accident diagnosis and repair model (STAMP in Section 3.2) suitable for the complex socio-technical system we envisage for future cell-based virtual utilities. From this analysis and the background material from deliverable D1.6 Information security models and their economics, we then reassess the dependability concerns related to the CRISP related scenarios of Chapter 2. The deliverable provides some novel ideas and models that we claim are

  8. Transit Operations Decision Support System (TODSS) core requirements evaluation and update recommendations. (United States)


    Transit Operations Decision Support Systems (TODSS) are systems designed to support dispatchers and others in real-time operations : management in response to incidents, special events, and other changing conditions in order to improve operating spee...

  9. Autonomous mobile robotic system for supporting counterterrorist and surveillance operations (United States)

    Adamczyk, Marek; Bulandra, Kazimierz; Moczulski, Wojciech


    Contemporary research on mobile robots concerns applications to counterterrorist and surveillance operations. The goal is to develop systems that are capable of supporting the police and special forces by carrying out such operations. The paper deals with a dedicated robotic system for surveillance of large objects such as airports, factories, military bases, and many others. The goal is to trace unauthorised persons who try to enter to the guarded area, document the intrusion and report it to the surveillance centre, and then warn the intruder by sound messages and eventually subdue him/her by stunning through acoustic effect of great power. The system consists of several parts. An armoured four-wheeled robot assures required mobility of the system. The robot is equipped with a set of sensors including 3D mapping system, IR and video cameras, and microphones. It communicates with the central control station (CCS) by means of a wideband wireless encrypted system. A control system of the robot can operate autonomously, and under remote control. In the autonomous mode the robot follows the path planned by the CCS. Once an intruder has been detected, the robot can adopt its plan to allow tracking him/her. Furthermore, special procedures of treatment of the intruder are applied including warning about the breach of the border of the protected area, and incapacitation of an appropriately selected very loud sound until a patrol of guards arrives. Once getting stuck the robot can contact the operator who can remotely solve the problem the robot is faced with.

  10. 2001 Industry Studies: Biotechnology

    National Research Council Canada - National Science Library


    .... The applications of biotechnology, such as medicine, agribusiness, forensics, informatics and the defense sector, offer many benefits, but also bring some risk, requiring public policy decisions...

  11. An Overview on Indian Patents on Biotechnology. (United States)

    Mallick, Anusaya; Chandra Santra, Subhas; Samal, Alok Chandra


    The application of biotechnology is a potential tool for mitigating the present and future fooding and clothing demands in developing countries like India. The commercialization of biotechnological products might benefiting the poor`s in developing countries are unlikely to be developed. Biotechnology has the potential to provide a wide range of products and the existing production skills in the industrial, pharmaceuticals and the agricultural sector. Ownership of the intellectual property rights is the key factors in determining the success of any technological invention, which was introduced in the market. It provides the means for technological progress to continue of the industry of the country. The new plans, animal varieties, new methods of treatments, new crops producing food articles as such are the inventions of biotechnology. Biotechnology is the result of the application of human intelligence and knowledge to the biological processes. Most of the tools of biotechnology have been developed, by companies, governments, research in- stitutes and universities in developed nations. These human intellectual efforts deserve protection. India is a developing country with advance biotechnology based segments of pharmaceutical and agricultural industries. The Trade Related Intellectual Property Rights (TRIPS) is not likely to have a significant impact on incentives for innovation creation in the biotechnology sectors. In the recent years, the world has seen the biotechnology sector as one of greatest investment area through the Patent Law and will giving huge profit in future. The Research and Development in the field of biotechnology should be encouraged for explor- ing new tools and improve the biological systems for interest of the common people. Priority should be given to generation, evaluation, protection and effective commercial utilization of tangible products of intellectual property in agriculture and pharmaceuticals. To support the future growth and

  12. Progress towards the 'Golden Age' of biotechnology. (United States)

    Gartland, K M A; Bruschi, F; Dundar, M; Gahan, P B; Viola Magni, M p; Akbarova, Y


    Biotechnology uses substances, materials or extracts derived from living cells, employing 22 million Europeans in a € 1.5 Tn endeavour, being the premier global economic growth opportunity this century. Significant advances have been made in red biotechnology using pharmaceutically and medically relevant applications, green biotechnology developing agricultural and environmental tools and white biotechnology serving industrial scale uses, frequently as process feedstocks. Red biotechnology has delivered dramatic improvements in controlling human disease, from antibiotics to overcome bacterial infections to anti-HIV/AIDS pharmaceuticals such as azidothymidine (AZT), anti-malarial compounds and novel vaccines saving millions of lives. Green biotechnology has dramatically increased food production through Agrobacterium and biolistic genetic modifications for the development of 'Golden Rice', pathogen resistant crops expressing crystal toxin genes, drought resistance and cold tolerance to extend growth range. The burgeoning area of white biotechnology has delivered bio-plastics, low temperature enzyme detergents and a host of feedstock materials for industrial processes such as modified starches, without which our everyday lives would be much more complex. Biotechnological applications can bridge these categories, by modifying energy crops properties, or analysing circulating nucleic acid elements, bringing benefits for all, through increased food production, supporting climate change adaptation and the low carbon economy, or novel diagnostics impacting on personalized medicine and genetic disease. Cross-cutting technologies such as PCR, novel sequencing tools, bioinformatics, transcriptomics and epigenetics are in the vanguard of biotechnological progress leading to an ever-increasing breadth of applications. Biotechnology will deliver solutions to unimagined problems, providing food security, health and well-being to mankind for centuries to come. Copyright © 2013

  13. Wireless networks of opportunity in support of secure field operations (United States)

    Stehle, Roy H.; Lewis, Mark


    Under funding from the Defense Advanced Research Projects Agency (DARPA) for joint military and law enforcement technologies, demonstrations of secure information transfer in support of law enforcement and military operations other than war, using wireless and wired technology, were held in September 1996 at several locations in the United States. In this paper, the network architecture, protocols, and equipment supporting the demonstration's scenarios are presented, together with initial results, including lessons learned and desired system enhancements. Wireless networks of opportunity encompassed in-building (wireless-LAN), campus-wide (Metricom Inc.), metropolitan (AMPS cellular, CDPD), and national (one- and two-way satellite) systems. Evolving DARPA-sponsored packet radio technology was incorporated. All data was encrypted, using multilevel information system security initiative (MISSI)FORTEZZA technology, for carriage over unsecured and unclassified commercial networks. The identification and authentication process inherent in the security system permitted logging for database accesses and provided an audit trail useful in evidence gathering. Wireless and wireline communications support, to and between modeled crisis management centers, was demonstrated. Mechanisms for the guarded transport of data through the secret-high military tactical Internet were included, to support joint law enforcement and crisis management missions. A secure World Wide Web (WWW) browser forms the primary, user-friendly interface for information retrieval and submission. The WWW pages were structured to be sensitive to the bandwidth, error rate, and cost of the communications medium in use (e.g., the use of and resolution for graphical data). Both still and motion compressed video were demonstrated, along with secure voice transmission from laptop computers in the field. Issues of network bandwidth, airtime costs, and deployment status are discussed.

  14. Spacelab Operations Support Room Space Engineering Support Team in the SL POCC During the IML-1 (United States)


    The primary payload for Space Shuttle Mission STS-42, launched January 22, 1992, was the International Microgravity Laboratory-1 (IML-1), a pressurized manned Spacelab module. The goal of IML-1 was to explore in depth the complex effects of weightlessness of living organisms and materials processing. Around-the-clock research was performed on the human nervous system's adaptation to low gravity and effects of microgravity on other life forms such as shrimp eggs, lentil seedlings, fruit fly eggs, and bacteria. Materials processing experiments were also conducted, including crystal growth from a variety of substances such as enzymes, mercury iodide, and a virus. The Huntsville Operations Support Center (HOSC) Spacelab Payload Operations Control Center (SL POCC) at the Marshall Space Flight Center (MSFC) was the air/ground communication channel used between the astronauts and ground control teams during the Spacelab missions. Featured is the Spacelab Operations Support Room Space Engineering Support team in the SL POCC during STS-42, IML-1 mission.

  15. Biotechnology essay competition: biotechnology and sustainable food practices. (United States)

    Peng, Judy; Schoeb, Helena; Lee, Gina


    Biotechnology Journal announces our second biotechnology essay competition with the theme "biotechnology and sustainable food practices", open to all undergraduate students. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. Psychological Support Operations and the ISS One-Year Mission (United States)

    Beven, G.; Vander Ark, S. T.; Holland, A. W.


    Since NASA began human presence on the International Space Station (ISS) in November 1998, crews have spent two to seven months onboard. In March 2015 NASA and Russia embarked on a new era of ISS utilization, with two of their crewmembers conducting a one-year mission onboard ISS. The mission has been useful for both research and mission operations to better understand the human, technological, mission management and staffing challenges that may be faced on missions beyond Low Earth Orbit. The work completed during the first 42 ISS missions provided the basis for the pre-flight, in-flight and post-flight work completed by NASA's Space Medicine Operations Division, while our Russian colleagues provided valuable insights from their long-duration mission experiences with missions lasting 10-14 months, which predated the ISS era. Space Medicine's Behavioral Health and Performance Group (BHP) provided pre-flight training, evaluation, and preparation as well as in-flight psychological support for the NASA crewmember. While the BHP team collaboratively planned for this mission with the help of all ISS international partners within the Human Behavior and Performance Working Group to leverage their collective expertise, the US and Russian BHP personnel were responsible for their respective crewmembers. The presentation will summarize the lessons and experience gained within the areas identified by this Working Group as being of primary importance for a one-year mission.

  17. Object and operation supported maintenance for mining equipment

    Directory of Open Access Journals (Sweden)

    Walter Bartelmus


    Full Text Available The paper aroused in answer to discussion in Mining Magazine (MM September 2011 and July/August 2013. The paper shows that discussion given in the MM issue July/August 2013 does not fulfill expectations expressed in MM issue 2011. The presented paper is the review on maintenance that is based on condition monitoring as tool for detection of faults and failure prevention. Fault and failure are regarded as inevitable during the machine operation as the process of wear and the process of degradation. The question is, if one can influence the wear and degradation process, using condition monitoring. The paper will present technology (in reference to cited papers which demonstrates that the use of the proper method can influence the wear and machine degradation process, using proper condition monitoring techniques and knowing scenarios of wear and degradation process, the maintenance can be rationalized. The presented paper shows possible improvements which are needed to fulfill expectations expressed in MM September 2011 and they are not taken into consideration in MM July/August 3013. These improvements can be fulfilling on the bases of object and operation supported maintenance.

  18. Use of Earth Observing Satellites for Operational Hazard Support (United States)

    Wood, H. M.; Lauritson, L.

    The National Oceanic and Atmospheric Administration (NOAA) relies on Earth observing satellite data to carry out its operational mission to monitor, predict, and assess changes in the Earth's atmosphere, land, and oceans. NOAA's National Environmental Satellite, Data, and Information Service (NESDIS) uses satellite data to help lessen the impacts of natural and man-made disasters due to tropical cyclones, flash floods, heavy snowstorms, volcanic ash clouds (for aviation safety), sea ice (for shipping safety), and harmful algal blooms. Communications systems on NOAA satellites are used to support search and rescue and to relay data from data collection platforms to a variety of users. NOAA's Geostationary (GOES) and Polar (POES) Operational Environmental Satellites are used in conjunction with other satellites to support NOAA's operational mission. While NOAA's National Hurricane Center is responsible for predicting tropical cyclones affecting the U.S. mainland, NESDIS continuously monitors the tropics world wide, relaying valuable satellite interpretations of tropical systems strength and position to users throughout the world. Text messages are sent every six hours for tropical cyclones in the Western Pacific, South Pacific, and Indian Oceans. To support the monitoring, prediction, and assessment of flash floods and winter storms, NESDIS sends out text messages alerting U.S. weather forecast offices whenever NOAA satellite imagery indicates the occurrence of heavy rain or snow. NESDIS also produces a 24-hour rainfall composite graphic image covering those areas affected by heavy precipitation. The International Civil Aviation Organization (ICAO) and other aviation concerns recognized the need to keep aviators informed of volcanic hazards. To that end, nine Volcanic Ash Advisory Centers (VAAC's) were created to monitor volcanic ash plumes within their assigned airspace. NESDIS hosts one of the VAAC's. Although the NESDIS VAAC's primary responsibility is the

  19. Nigerian Journal of Biotechnology

    African Journals Online (AJOL)

    Nigerian Journal of Biotechnology is a publisher of multidisciplinary peer-reviews original research works and critical reviews on interdisciplinary studies in Biotechnology, Agriculture, Food and Environment interface; and is published twice a year. It serves scientists in the field of Agriculture, Food science and Technology; ...

  20. Biotechnology in China

    National Research Council Canada - National Science Library

    Hamer, Dean H; Kung, Shain-dow


    ... and Shain-dow Kung Center for Agricultural Biotechnology Maryland Biotechnology Institute Department of Botany University of Maryland College Park, Maryland Committee on Scholarly Communication with the People's Republic of China National Academy of Sciences National Academy Press Washington, DC 1989 i Copyrightthe cannot be not from bo...

  1. Local DER Driven Grid Support by Coordinated Operation of Devices

    International Nuclear Information System (INIS)

    Warmer, C.J.; Kamphuis, I.G.


    In the traditional operation of electricity networks the system operator has a number of ancillary services available for preservation of system balance. These services are called upon near real-time, after the planning phase. Ancillary services consist of regulating power, reserve capacity and emergency capacity, each with their own characteristics. Regulating power is deployed via load frequency control. Reserve capacity is used to release regulating power and can be called upon to maintain a balance or to counterbalance or resolve transmission restrictions. Both are traded at the Dutch energy market under an auction model with a single buyer (TenneT). Emergency capacity is rewarded on the basis of accessibility/availability within 15 minutes. In local electricity networks neither planning nor ancillary services exist. Planning is done by aggregation into large customer groups. For ancillary services one relies on the system operation as sketched above. In local electricity networks with a large share of distributed generation the costs of keeping the electricity system reliable and stable will increase further and technical problems may arise. The European SmartGrids initiative responds to these challenges in their strategic research agenda. One of the issues addressed in this agenda is the changing role of the distribution grid in which users get a more active role. One opportunity is the introduction of ancillary-type services at the distribution level, utilizing different types of producing and consuming devices in the local network, in order to make the total system more dependable. Distributed generation has a number of characteristics that are similar to characteristics of consumption. Part of it is intermittent / variable, although to a large extent predictable (PV, wind versus lighting, electronic devices). Another part is task-driven (micro-CHP versus electrical heating). Yet another part is controllable or shiftable in time. And storage can behave both

  2. Mobile Operator Supports Refugees and Disabled in Georgia

    Directory of Open Access Journals (Sweden)

    Zviad KIRTAVA


    Full Text Available Collapse of USSR and declaration of independence by Georgia was followed by ethnic conflicts provoked by Russia, and de-facto loosing of South Ossetia and Abkhazia, with about 300,000 internally displaced persons (IDPs. New wave of tens of thousands IDPs - mainly from South Ossetia and Shida Kartli - have emerged since recent Russian occupation of Georgian territories in August 2008. Refugees, considering their economical and psycho-social problems, are needy for communication as cell phones often remain a main hope for establishing contacts and new social networking. One of the major mobile operator (MO – Geocell introduced during 4 months special tariff for refugees - 0, 09 GEL (0,044€ per min –70% reduction of basic rate. Around 56% of refugees have used that emergency relief measure. MO also helps deaf-mute persons by providing special SMS rate - 0, 02 GEL (1/3 of usual and supporting computer center where it educates such disabled with future employment prospects (7 persons – at MO office.

  3. Operator support and diagnostic reasoning in an industrial process

    Energy Technology Data Exchange (ETDEWEB)

    Aaker, O.


    Efficient use of energy in production plants requires that the various processes are well controlled. The main focus of this doctoral thesis is on detection of errors and malfunctions using analytical redundancy and on state estimation using an open loop nonlinear model. A ``residual`` is present if a system does not behave as expected, or if a certain rule is violated. ``Reasoning`` is the action of finding process malfunctions based on observed residuals. The thesis applies a new formalism for comparing diagnostic reasoning methods both in terms of what knowledge is used and how it is used, and suggests a formal model of what is known about the process. The formalism is used to illustrate the difference between diagnostic reasoning based on physically interconnected process units and streams, and reasoning about goals and functions for finding a diagnosis. As an example of application, results and experiences from a test implementation using an open loop model for operator support in a complex fertilizer factory are reported. 108 refs., 61 figs., 37 tabs.

  4. Decision support system for the operating room rescheduling problem. (United States)

    van Essen, J Theresia; Hurink, Johann L; Hartholt, Woutske; van den Akker, Bernd J


    Due to surgery duration variability and arrivals of emergency surgeries, the planned Operating Room (OR) schedule is disrupted throughout the day which may lead to a change in the start time of the elective surgeries. These changes may result in undesirable situations for patients, wards or other involved departments, and therefore, the OR schedule has to be adjusted. In this paper, we develop a decision support system (DSS) which assists the OR manager in this decision by providing the three best adjusted OR schedules. The system considers the preferences of all involved stakeholders and only evaluates the OR schedules that satisfy the imposed resource constraints. The decision rules used for this system are based on a thorough analysis of the OR rescheduling problem. We model this problem as an Integer Linear Program (ILP) which objective is to minimize the deviation from the preferences of the considered stakeholders. By applying this ILP to instances from practice, we determined that the given preferences mainly lead to (i) shifting a surgery and (ii) scheduling a break between two surgeries. By using these changes in the DSS, the performed simulation study shows that less surgeries are canceled and patients and wards are more satisfied, but also that the perceived workload of several departments increases to compensate this. The system can also be used to judge the acceptability of a proposed initial OR schedule.

  5. Stress and Psychological Support in Modern Military Operations (Stress et aide psychologique dans les operations militaires modernes)

    National Research Council Canada - National Science Library


    NATO Task Group HFM-081/RTG on "Stress and Psychological Support in Modern Military Operations" has produced, in the form of a Military Leaders Guide, a series of guidelines for psychological support...

  6. Modern Biotechnology in China (United States)

    Wang, Qing-Zhao; Zhao, Xue-Ming

    In recent years, with the booming economy, the Chinese government has increased its financial input to biotechnology research, which has led to remarkable achievements by China in modern biotechnology. As one of the key parts of modern biotechnology, industrial biotechnology will be crucial for China's sustainable development in this century. This review presents an overview of Chinese industrial biotechnology in last 10 years. Modern biotechnology had been classified into metabolic engineering and systems biology framework. Metabolic engineering is a field of broad fundamental and practical concept so we integrated the related technology achievements into the real practices of many metabolic engineering cases, such as biobased products production, environmental control and others. Now metabolic engineering is developing towards the systems level. Chinese researchers have also embraced this concept and have contributed invaluable things in genomics, transcriptomics, proteomics and related bioinformatics. A series of advanced laboratories or centers were established which will represent Chinese modern biotechnology development in the near future. At the end of this review, metabolic network research advances have also been mentioned.

  7. Transit Operations Decision Support System (TODSS) core requirements prototype development case study and lessons learned. (United States)


    Transit Operations Decision Support Systems (TODSS) are systems designed to support dispatchers and others in real-time operations : management in response to incidents, special events, and other changing conditions. As part of a joint Federal Transi...

  8. Panel 6 -- Contracting for Support of Military Operations

    National Research Council Canada - National Science Library

    Greenfield, Victoria; Dunn, Richard L; Parsons, Jeffrey P


    .... The conflicts include the American Revolution, the Mexican-American war, the Civil War, World War I, World War II, the Korean War, the Vietnam War, the Balkans, Operation Desert Storm, and Operation Iraqi Freedom. Dr...

  9. A computerized operator support system for BWR power plant during normal and abnormal conditions

    International Nuclear Information System (INIS)

    Monta, K.; Sato, N.; Tsunoyama, S.; Sekimizu, K.; Mori, N.


    A computerized operator support system for BWR was developed based on the operators tasks which are divided into problem solving and controlling. Problem solving comprises fault managing and planning tasks. One of the operator supports for the problem solving is the automatic diagnostic support. However, the operator supports for controlling tasks are still important, e.g. to support its rule memory and rule execution. In the system presented here, operator supports are considered for both of these two categories. In the paper two subsystems for the latter are mainly described. (author)

  10. Numerical Model Metrics Tools in Support of Navy Operations (United States)

    Dykes, J. D.; Fanguy, P.


    Increasing demands of accurate ocean forecasts that are relevant to the Navy mission decision makers demand tools that quickly provide relevant numerical model metrics to the forecasters. Increasing modelling capabilities with ever-higher resolution domains including coupled and ensemble systems as well as the increasing volume of observations and other data sources to which to compare the model output requires more tools for the forecaster to enable doing more with less. These data can be appropriately handled in a geographic information system (GIS) fused together to provide useful information and analyses, and ultimately a better understanding how the pertinent model performs based on ground truth.. Oceanographic measurements like surface elevation, profiles of temperature and salinity, and wave height can all be incorporated into a set of layers correlated to geographic information such as bathymetry and topography. In addition, an automated system that runs concurrently with the models on high performance machines matches routinely available observations to modelled values to form a database of matchups with which statistics can be calculated and displayed, to facilitate validation of forecast state and derived variables. ArcMAP, developed by Environmental Systems Research Institute, is a GIS application used by the Naval Research Laboratory (NRL) and naval operational meteorological and oceanographic centers to analyse the environment in support of a range of Navy missions. For example, acoustic propagation in the ocean is described with a three-dimensional analysis of sound speed that depends on profiles of temperature, pressure and salinity predicted by the Navy Coastal Ocean Model. The data and model output must include geo-referencing information suitable for accurately placing the data within the ArcMAP framework. NRL has developed tools that facilitate merging these geophysical data and their analyses, including intercomparisons between model

  11. Application of modern technology for fieldwork support in network operations

    International Nuclear Information System (INIS)

    Eggen, Arnt Ove; Langdal, Bjoern Inge


    Demands for rational and efficient operation and management in several business sectors such as power-, oil- and gas industry, telecommunication, water and multi-utility has lead to big changes for personnel in charge of managing the infrastructure and for the field-workers. Contractors providing services for the large power network companies do not have the local knowledge about construction projects, and there are increased demands on efficiency related to completion, documentation and reporting. This implies a need for transmission of knowledge and experiences between office and the field, and support for fieldwork in the form of applications using various technological possibilities. Field solutions that have well-developed technical and organisational properties will make administration of the infrastructure more efficient, and raise the quality of the work. The choice of mobile service will always be a compromise between several different wishes and needs. The properties of hardware, software and communication options will often influence possible choices in the respective fields. As an important step in testing of hardware, software and communication, some prototypes have been developed for Pocket Pc. The prototypes 'Befaring' and 'HelikopterBefaring' have been chosen because they contain many of the elements that are important in a mobile solution. In addition a prototype for internet applications has been developed ('HelikopterBefaringMottak') and a Windows application ('HelikopterBefaringPresentasjon') in order to visualise the received and managed information sent from the mobile units. The technological development both in software, hardware, GPS and mobile telephones is extremely rapid, and the first mobile solutions with Pocket Pc, mobile telephone and GPS in one integrated unit is already on the market (ml)

  12. Operation and safety decision-making support expert system in NPP

    International Nuclear Information System (INIS)

    Wei Yanhui; Su Desong; Chen Weihua; Zhang Jianbo


    The article first reviewed three operation support systems currently used in NPP: real-time information surveillance system, important equipment surveillance system and plant process control and monitoring system, then presents the structure and function of three expert support sub-systems (intelligent alarm monitoring system, computer-based operating procedure support system, safety information expert decision support system). Finally the article discussed the meaning of a kind of operation decision making support system. (authors)

  13. Traditional Chinese Biotechnology (United States)

    Xu, Yan; Wang, Dong; Fan, Wen Lai; Mu, Xiao Qing; Chen, Jian

    The earliest industrial biotechnology originated in ancient China and developed into a vibrant industry in traditional Chinese liquor, rice wine, soy sauce, and vinegar. It is now a significant component of the Chinese economy valued annually at about 150 billion RMB. Although the production methods had existed and remained basically unchanged for centuries, modern developments in biotechnology and related fields in the last decades have greatly impacted on these industries and led to numerous technological innovations. In this chapter, the main biochemical processes and related technological innovations in traditional Chinese biotechnology are illustrated with recent advances in functional microbiology, microbial ecology, solid-state fermentation, enzymology, chemistry of impact flavor compounds, and improvements made to relevant traditional industrial facilities. Recent biotechnological advances in making Chinese liquor, rice wine, soy sauce, and vinegar are reviewed.



    Hossain, Ferdaus; Onyango, Benjamin M.; Adelaja, Adesoji O.; Schilling, Brian J.; Hallman, William K.


    Significant divergence exists in public opinions about biotechnology. Although there is broad support for plant biotechnology for health benefits, opinions differ on the issue of animal genetics for pure economic benefits. While some are opposed to it, many are undecided about genetically modified foods. Considerable skepticism exists about scientists, corporations and government which have negative influence on public acceptance of food biotechnology. Consumers' personal attributes have sign...

  15. Fungal biodiversity to biotechnology. (United States)

    Chambergo, Felipe S; Valencia, Estela Y


    Fungal habitats include soil, water, and extreme environments. With around 100,000 fungus species already described, it is estimated that 5.1 million fungus species exist on our planet, making fungi one of the largest and most diverse kingdoms of eukaryotes. Fungi show remarkable metabolic features due to a sophisticated genomic network and are important for the production of biotechnological compounds that greatly impact our society in many ways. In this review, we present the current state of knowledge on fungal biodiversity, with special emphasis on filamentous fungi and the most recent discoveries in the field of identification and production of biotechnological compounds. More than 250 fungus species have been studied to produce these biotechnological compounds. This review focuses on three of the branches generally accepted in biotechnological applications, which have been identified by a color code: red, green, and white for pharmaceutical, agricultural, and industrial biotechnology, respectively. We also discuss future prospects for the use of filamentous fungi in biotechnology application.


    Directory of Open Access Journals (Sweden)

    John I. Bruce


    Full Text Available Biotechnology as a science includes various aspects of the management and manipulation of biological systems. Recent advances in immunology, molecular biology, cell culture and other associated areas provide an opportunity for scientists to move biology out of the laboratory and into the realms of society. This has many implications which mankind on a whole may not be prepared to cope with at this time. This new capability has been referred to as "Biotechnology". Biotechnology has also been defined as "the integrated use of biochemistry, microbiology, and chemical engineering in order to achieve the capacities of microbes and culture cells". Genetic engineering which includes gene splicing and recombinant DNA-cloning is an example of a recent offshoot of biotechnology. Because of the advent of biotechnology, one can now think of the prospect of engineering tomorrows vaccines. In the past, vaccine development has been laborious and in many instances an unrewarding task. After years of effort only a handful of safe, effective vaccines have emerged. In the biotechnology arena, new methodologies and strategies for immunizing humans and domestic animals against infectious diseases are providing new hope for discovering successful vaccines. While most of the effort in the past has focused on viral vaccine development, attention is now being directed towards vaccines for protection against parasitic diseases. Currently, considerable effort is being made to develop vaccines for malaria, coccidiosis (in fowl, cholera, malaria, schistosomiasis and trypanosomiasis among others.

  17. Medical Equipment Used to Support Operations in Southwest Asia (United States)


    Microbiology Psychiatry/Mental Health Pediatrics Radiology* Prosthesis Trauma Surgery (General, Orthopedic, Urologic, Obstetrics and Gynecology...because they lacked Class VIII supply systems integration. (The Class VIII medical commodity group includes pharmaceutical, medical-surgical, dental ...Scanners Chemistry Analyzers C-Arms Hematology Analyzers Fluid Warmers Lab Analyzers Operating Room Lights Dental Operating Units Dental Compressors

  18. GNSS Wristwatch Device for Networked Operations Supporting Location Based Services

    National Research Council Canada - National Science Library

    Brown, Alison; Brown, Peter K


    .... It includes a low-power GPS sensor, a flash memory, and a ZigBee wireless data link. The design of the device was selected to minimize the power drain to allow operation for extended periods of time...

  19. Vietnam 1963-1973: Ten Years of Operational Contract Support (United States)


    determine which contractors operate within the market.29 This study uses the framework of the microeconomic phenomenon of monopsony to explain the...increases. Third, when the size of the military decreases, then the dependence on PMCs increases. In order to 27Edwin Mansfield, Microeconomics ...operates in an imbalanced market where the U.S. Government becomes the sole buyer on the demand side. This is a microeconomic phenomenon known as

  20. Operationally Responsive Spacelift: Supporting a Seven-Day Launch Schedule (United States)


    release; distribution is unlimited 12b. DISTRIBUTION CODE A 13. ABSTRACT (maximum 200 words) In 2001, the Air Force issued AFSPC 001-01...14. SUBJECT TERMS Operationally Responsive Space 15. NUMBER OF PAGES 81 16. PRICE CODE 17. SECURITY CLASSIFICATION OF REPORT...Joe Nemeth , both government servants at Vandenberg AFB, for being willing to dig up range operations documents that were not available on the

  1. Weather Information Services supporting Civilian UAS Operations, Phase I (United States)

    National Aeronautics and Space Administration — We build a system that supports the weather information needs of Unmanned Aircraft Systems (UAS) planning to fly in the National Airspace System (NAS). This weather...

  2. Commercialization of animal biotechnology. (United States)

    Faber, D C; Molina, J A; Ohlrichs, C L; Vander Zwaag, D F; Ferré, L B


    Commercialization of animal biotechnology is a wide-ranging topic for discussion. In this paper, we will attempt to review embryo transfer (ET) and related technologies that relate to food-producing mammals. A brief review of the history of advances in biotechnology will provide a glimpse to present and future applications. Commercialization of animal biotechnology is presently taking two pathways. The first application involves the use of animals for biomedical purposes. Very few companies have developed all of the core competencies and intellectual properties to complete the bridge from lab bench to product. The second pathway of application is for the production of animals used for food. Artificial insemination (AI), embryo transfer, in vitro fertilization (IVF), cloning, transgenics, and genomics all are components of the toolbox for present and future applications. Individually, these are powerful tools capable of providing significant improvements in productivity. Combinations of these technologies coupled with information systems and data analysis, will provide even more significant change in the next decade. Any strategies for the commercial application of animal biotechnology must include a careful review of regulatory and social concerns. Careful review of industry infrastructure is also important. Our colleagues in plant biotechnology have helped highlight some of these pitfalls and provide us with a retrospective review. In summary, today we have core competencies that provide a wealth of opportunities for the members of this society, commercial companies, producers, and the general population. Successful commercialization will benefit all of the above stakeholders. Copyright 2002 Elsevier Science Inc.

  3. Operating System Support for High-Performance Solid State Drives

    DEFF Research Database (Denmark)

    Bjørling, Matias

    of the operating system in reducing the gap, and enabling new forms of communication and even co-design between applications and high-performance SSDs. More specifically, we studied the storage layers within the Linux kernel. We explore the following issues: (i) what are the limitations of the legacy block...... a form of application-SSD co-design? What are the impacts on operating system design? (v) What would it take to provide quality of service for applications requiring millions of I/O per second? The dissertation consists of six publications covering these issues. Two of the main contributions...

  4. 101st Sustainment Brigade Supports Operation United Assistance (United States)


    Petty, and Maj. Benjamin Polanco Jr. Capt. Shawn Palmer, a biochemist with the 1st Area Medical Laboratory from Aberdeen Proving Ground, Maryland...I order- ing cycle that resulted in predictable, sustainable, and timely delivery of rations. Operational rations were also stored in a warehouse

  5. Biotechnological production of vanillin. (United States)

    Priefert, H; Rabenhorst, J; Steinbüchel, A


    Vanillin is one of the most important aromatic flavor compounds used in foods, beverages, perfumes, and pharmaceuticals and is produced on a scale of more than 10 thousand tons per year by the industry through chemical synthesis. Alternative biotechnology-based approaches for the production are based on bioconversion of lignin, phenolic stilbenes, isoeugenol, eugenol, ferulic acid, or aromatic amino acids, and on de novo biosynthesis, applying fungi, bacteria, plant cells, or genetically engineered microorganisms. Here, the different biosynthesis routes involved in biotechnological vanillin production are discussed.

  6. Agave biotechnology: an overview. (United States)

    Nava-Cruz, Naivy Y; Medina-Morales, Miguel A; Martinez, José L; Rodriguez, R; Aguilar, Cristóbal N


    Agaves are plants of importance both in Mexican culture and economy and in other Latin-American countries. Mexico is reported to be the place of Agave origin, where today, scientists are looking for different industrial applications without compromising its sustainability and preserving the environment. To make it possible, a deep knowledge of all aspects involved in production process, agro-ecological management and plant biochemistry and physiology is required. Agave biotechnology research has been focusing on bio-fuels, beverages, foods, fibers, saponins among others. In this review, we present the advances and challenges of Agave biotechnology.

  7. Colloids in Biotechnology

    CERN Document Server

    Fanun, Monzer


    Colloids have come a long way from when Thomas Graham coined the term colloid to describe 'pseudo solutions'. This book enables scientists to close the gap between extensive research and translation into commercial options in biomedicine and biotechnology. It covers biosurfactants and surface properties, phase behavior, and orientational change of surfactant mixtures with peptides at the interface. It also covers adsorption of polymers and biopolymers on the surface and interface, discusses colloidal nanoparticles and their use in biotechnology, and delves into bioadhesion and microencapsulati

  8. Sleep Supports Inhibitory Operant Conditioning Memory in "Aplysia" (United States)

    Vorster, Albrecht P. A.; Born, Jan


    Sleep supports memory consolidation as shown in mammals and invertebrates such as bees and "Drosophila." Here, we show that sleep's memory function is preserved in "Aplysia californica" with an even simpler nervous system. Animals performed on an inhibitory conditioning task ("learning that a food is inedible") three…

  9. Making Risk Models Operational for Situational Awareness and Decision Support

    International Nuclear Information System (INIS)

    Paulson, P.R.; Coles, G.; Shoemaker, S.


    We present CARIM, a decision support tool to aid in the evaluation of plans for converting control systems to digital instruments. The model provides the capability to optimize planning and resource allocation to reduce risk from multiple safety and economic perspectives. (author)

  10. Supporting Marine Corps Enhanced Company Operations : a quantitative analysis


    Hinkson, Daniel S.


    Approved for public release; distribution is unlimited This research explores the capability requirements for the employment of a Marine Rifle Company organized to conduct Enhanced Company Operations (ECO). It uses a simulation model, built in an agent-based simulation tool called MANA, to evaluate the logistical impact of ECO on a Marine Expeditionary Unit (MEU). ECO involves reorganizing and augmenting the traditional rifle company in a manner that contributes to "enhanced" command and ...

  11. Soldier Cognitive Processes: Supporting Teleoperated Ground Vehicle Operations (United States)


    equipment items. Capitalizing on requirements and ideas of military units, deployed in combat and facing complex reconnaissance, security, and...operator so they remember to apply it to the robot. Another example is recognizing an IED. A Soldier might already know about telltale signs of...employ the ground robotic vehicle imposes a cognitive load on top of other military skills, perceptual decision-making skills, and communication

  12. Expeditionary Logistics: How the Marine Corps Supports Its Expeditionary Operations (United States)


    services with regard to expeditionary operations (Kundra, Brown, & Donaldson, 2014). An exhaustive search of professional and trade journals provided...Marines then deployed to the Nation of Vietnam for the next big conflict. Both Korea and Vietnam greatly changed the way the U.S. Marine Corps...stock for exercise African Lion . 43 Figure 11. MPF Offload (from The mission of the MEB evolved over time from transportation

  13. Disclosing Biology Teachers' Beliefs about Biotechnology and Biotechnology Education (United States)

    Fonseca, Maria Joao; Costa, Patricio; Lencastre, Leonor; Tavares, Fernando


    Teachers have been shown to frequently avoid addressing biotechnology topics. Aiming to understand the extent to which teachers' scarce engagement in biotechnology teaching is influenced by their beliefs and/or by extrinsic constraints, such as practical limitations, this study evaluates biology teachers' beliefs about biotechnology and…

  14. Concepts in Biotechnology An Affordable Overview of Biotechnology ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 2; Issue 9. Concepts in Biotechnology An Affordable Overview of Biotechnology Through Self Study ... Author Affiliations. Narayan S Punekar1. Molecular Enzymology Group, Biotechnology Centre, Indian Institute of Technology, Mumbai 400 076, India.

  15. Antagonistic effect of alkaloids and saponins on bioactivity in the quinine tree (Rauvolfia caffra sond.): further evidence to support biotechnology in traditional medicinal plants. (United States)

    Milugo, Trizah K; Omosa, Leonida K; Ochanda, James O; Owuor, Bethwell O; Wamunyokoli, Fred A; Oyugi, Julius O; Ochieng, Joel W


    The Quinine tree (Rauvolfia caffra) is used as a medicinal plant among traditional communities in many countries to manage tumors and other diseases associated with oxidative stress. To validate indigenous knowledge and possibly position this herb for technology uptake and utilization, we established the level of antioxidant activity in R. caffra, and probed for the presence of associated phytochemicals. Antioxidant activity was determined on 1,1-diphenyl-2-picrylhydrazyl (DPPH) while major phytochemicals were identified by multiple tests on methanol fractions. R. caffra showed promise as a cure, with antioxidant activity comparable to the commercially used drug quercetin (R. caffra = 79.7% ±1.9; quercetin = 82.6% ± 2.0). However, we found two phytochemicals with possible antagonistic effect: co-occurrence of alkaloids and saponins significantly reduced antioxidant activity (alkaloids only = 63%; alkaloids plus saponins = 15%; steroids, terpenoids and cardiac glycosides = 82%), thus alkaloids and saponins should be exclusive to each other in drug formulations. Antagonistic relationship among phytochemicals would affect the efficacy of crude extracts as used in traditional medicine. Unlike in herbal medicine, use of modern biotechnology in extraction, purification and design of optimal combinations will ensure efficient drug formulations with optimum bioactivity and minimum toxicity. Metabolic pathway engineering under a controlled environment may optimize availability of desired compounds.

  16. Forces for Good? British Military Masculinities on Peace Support Operations


    Duncanson, Claire


    This thesis is situated at the intersection of Feminist International Relations, Critical Security Studies and Gender Studies. It takes as its starting point – and offers a challenge to – the feminist contention that soldiers cannot be peacekeepers due to hegemonic constructions of military masculinity associated with the skills and practices of combat. It problematises this assumption by investigating whether involvement in the practices of conflict resolution on Peace Support...

  17. Evaluating Combat Service Support Transformation for the Contemporary Operating Environment (United States)


    Generation IV/V enhanced thermal /image intensification night vision devices worn by every member on the convoy enable their night driving. His company...units did not have the stockage level of spare parts that they needed for the “march up” on hand. The Prescribed Load Lists (PLL/unit level) and...Authorized Stockage Lists (ASL/direct support level) were insufficient for the amount of use (both hours and miles) on the tracked and tactical wheeled

  18. National Center for Biotechnology Information (United States)

    ... to NCBI Sign Out NCBI National Center for Biotechnology Information Search database All Databases Assembly Biocollections BioProject ... Search Welcome to NCBI The National Center for Biotechnology Information advances science and health by providing access ...

  19. Modern Advances to the Modular Fly-Away Kit (MFLAK) to Support Maritime Interdiction Operations

    National Research Council Canada - National Science Library

    Cross, Eric C


    This thesis will test the performance of an end-to-end network solution designed to augment Maritime Interdiction Operations that support boarding parties and their near real time communications with supporting agencies...

  20. Operating System Support for Shared Hardware Data Structures (United States)


    processor with DDR -200 RAM had a memory latency around 52 CPU cycles. Five years ago, a 4 GHz processor with DDR2-800 RAM had a memory latency around 220...LIFO: last-in, first-out LRU: least recently used OS: operating system PAA: priority-aware assignment RAM : random-access memory RC: random-access memory ( RAM )—such as SPM—that are the same size. To implement insert, the HWDS stores the key in the CAM at an available location, and

  1. Wood production, wood technology, and biotechnological impacts.



    In the year 2001, Prof. Dr. Ursula Kües was appointed at the Faculty of Forest Sciences and Forest Ecology of the Georg-August-University Göttingen to the chair Molecular Wood Biotechnology endowed by the Deutsche Bundesstiftung Umwelt (DBU). Her group studies higher fungi in basic and applied research. Research foci are on mushroom development and on fungal enzymes degrading wood and their applications in wood biotechnology. This book has been edited to thank the DBU for all support given to...

  2. Biotechnological advances in Lilium

    NARCIS (Netherlands)

    Bakhshaie, Mehdi; Khosravi, Solmaz; Azadi, Pejman; Bagheri, Hedayat; Tuyl, van Jaap M.


    Modern powerful techniques in plant biotechnology have been developed in lilies (Lilium spp., Liliaceae) to propagate, improve and make new phenotypes. Reliable in vitro culture methods are available to multiply lilies rapidly and shorten breeding programs. Lilium is also an ideal model plant to

  3. TSCA Biotechnology Notifications Status (United States)

    This Notifications Table lists only those submissions received under the Biotechnology Regulation, beginning in 1998. From the Table, you can link to a brief summary of select submission and, in many cases, to a fact sheet on the decision reached by OPPT.

  4. Biotechnology of trees: Chestnut (United States)

    C.D. Nelson; W.A. Powell; S.A. Merkle; J.E. Carlson; F.V. Hebard; N Islam-Faridi; M.E. Staton; L. Georgi


    Biotechnology has been practiced on chestnuts (Castanea spp.) for many decades, including vegetative propagation, controlled crossing followed by testing and selection, genetic and cytogenetic mapping, genetic modifi cation, and gene and genome sequencing. Vegetative propagation methods have ranged from grafting and rooting to somatic embryogenesis, often in...

  5. Biotechnology in weed control (United States)

    Biotechnology can be used to enhance the management of weeds in several ways. Crops have been made resistant to herbicides by inserting transgenes that impart herbicide resistance into the plant genome. Glyphosate and glufosinate-resistant crops are commercialized in North America and crops made res...

  6. African Journal of Biotechnology

    African Journals Online (AJOL)

    The African Journal of Biotechnology (AJB), a new broad-based journal, was founded on two key tenets: To publish the most exciting research in all areas of applied biochemistry, industrial microbiology, molecular biology, genomics and proteomics, food and agricultural technologies, and metabolic engineering. Secondly ...

  7. Biotechnology: interferon patent contested. (United States)

    Earl, C; Beardsley, T

    Biogen, a biotechnology company based in Cambridge, Mass., and Geneva, Switzerland, has been notified by the European Patent Office that it will receive a product patent for its alpha interferon synthesized by recombinant DNA technology. Genentech, a San Francisco company which claims priority for producing mature interferon, is planning a vigorous appeal of the decision.

  8. Biotechnology and Innovation Systems

    International Development Research Centre (IDRC) Digital Library (Canada)

    His main research activities are connected to science and technology policies and national and local systems of innovation in less developed countries. ...... of the Brazilian productive structure in energy-related areas – bio-fuels, oil, and so on – biotechnology research has started to target energy-related activities. However ...

  9. Biotechnological Innovations in Aquaculture

    Directory of Open Access Journals (Sweden)

    Mangesh M. Bhosale


    Full Text Available Aquaculture is gaining commendable importance to meet the required protein source for ever increasing human population. The aquaculture industry is currently facing problems on developing economically viable production systems by reducing the impact on environment. Sustainable and enhanced fish production from aquaculture may be better achieved through application of recent biotechnological innovations. Utilisation of transgenic technology has led to production of fishes with faster growth rate with disease resistance. The full advantage of this technology could not be achieved due to concern of acceptance for Genetically Modified Organisms (GMOs. The biotechnological intervention in developing plant based feed ingredient in place of fish meal which contain high phosphorus is of prime area of attention for fish feed industry. The replacement of fish meal will also reduce fish feed cost to a greater extent. Year round fish seed production of carps through various biotechnological interventions is also need of the hour. This paper discusses technical, environmental and managerial considerations regarding the use of these biotechnological tools in aquaculture along with the advantages of research application and its commercialization.

  10. Biotechnologies and Human Dignity (United States)

    Sweet, William; Masciulli, Joseph


    In this article, the authors review some contemporary cases where biotechnologies have been employed, where they have had global implications, and where there has been considerable debate. The authors argue that the concept of dignity, which lies at the center of such documents as the 2005 Universal Declaration on Bioethics and Human Rights, the…

  11. Medical Biotechnology: Problems and Prospects in Bangladesh

    Directory of Open Access Journals (Sweden)

    Shaikh Mizan


    Full Text Available Biotechnology is the knowledge and techniques of developing and using biological systems for deriving special products and services. The age-old technology took a new turn with the advent of recombinant DNA techniques, and boosted by the development of other molecular biological techniques, cell culture techniques and bioinformatics. Medical biotechnology is the major thrust area of biotechnology. It has brought revolutions in medicine – quick methods for diagnosing diseases, generation of new drugs and vaccines, completely novel approach of treatment are only a few to mention. The industrial and financial bulk of the industry mushroomed very rapidly in the last three decades, led by the USA and western advanced nations. Asian countries like China, India, South Korea, Taiwan and Singapore joined late, but advancing forward in a big way. In all the Asian countries governments supported the initiatives of the expert and entrepreneur community, and invested heavily in its development. Bangladesh has got great potential in developing biotechnology and reaping its fruits. However, lack of commitment and patriotism, and too much corruption and irresponsibility in political and bureaucratic establishment are the major hindrance to the development of biotechnology in Bangladesh.

  12. Employing Special Operations Forces to Conduct Deception in Support of Shaping and Decisive Operations

    National Research Council Canada - National Science Library

    LeMire, Guy


    .... The increased demand for intelligence, information superiority, as well as the increased need for operational security to conduct successful deception also present a significant challenge to military planners...

  13. Eifel field operation campaign supporting Moon Mars and NEO exploration (United States)

    Kamps, Oscar; Foing, Bernard H.; Offringa, Marloes


    As follow-up on the 2009 Eifel field campaign new field tests with our ExoGeoLab lander were conducted in November 2015 and February 2016. The two phase campaign was used to test the usability of a mock-up lander as test bench for experiments and its remote control in a Moon, Mars analogue environment. In a real mission such a lander could be used in a robotic or manned mission as scientific tool for scientists on Earth to do preliminary study on in-situ collected rocks. This could be useful for example for a sample return mission where scientists on Earth can determine if sample is interesting enough for a more detailed study. The prototype lander is one of the components of the ExoGeoLab project from ESA and ILEWG. Several student projects have prepared the lander for a geological field campaign in lunar and Martian analogue terrain. The lander can be divided in three sections which are used to store several components of the lander. The lower compartment can be used to store a rover or used as laboratory. The middle compartment is used for the lander computer(s), spectrometers and the associated cables. The top plate is used for a telescope which in our case is used to observe the environment around the lander and to guide astronauts during their EVA. As closest volcanic are there is chosen to do the Eifel area, Germany. Several stages of volcanism from Devon till Quaternary resulted in a variation of rocks which is analogue to volcanic rocks from Moon, Mars and other near Earth objects. Several topics we would like to test were pre-defined. Functional tests and demo were performed at European astronaut centre prior to the campaign. The latest updates with respect to the remote control were tested. The pressurised transport vehicle was equipped as remote base for (scientific) support during the campaign. The new instrument set-up were tested and some spectra were measured on collected rocks. The telescope was used to study the environment around the lander

  14. Development of a computerized operator support system for BWR power plant

    International Nuclear Information System (INIS)

    Monta, K.; Sekimizu, K.; Sato, N.; Araki, T.; Mori, N.


    A computerized operator support system for BWR power plant has been developed since 1980 supported by the Japanese government. The main functions of the systems are post trip operational guidance, disturbance analysis, standby system management, operational margin monitoring and control rod operational guidance. The former two functions aim at protection against incidents during operation of nuclear power plants and the latter three functions aim at their prevention. As the final stage of the development, these functions are combined with the plant supervision function and are organized as an advanced man-machine interface for BWR power plant. During the above process, operator task analyses are performed to enable synthesis of these support functions for right fit to operator tasks and to realize a hierarchical structure for CRT displays for right fit to operators cognitive needs. (author)

  15. Sleep supports inhibitory operant conditioning memory inAplysia. (United States)

    Vorster, Albrecht P A; Born, Jan


    Sleep supports memory consolidation as shown in mammals and invertebrates such as bees and Drosophila. Here, we show that sleep's memory function is preserved in Aplysia californica with an even simpler nervous system. Animals performed on an inhibitory conditioning task ("learning that a food is inedible") three times, at Training, Retrieval 1, and Retrieval 2, with 17-h intervals between tests. Compared with Wake animals, remaining awake between Training and Retrieval 1, Sleep animals with undisturbed post-training sleep, performed significantly better at Retrieval 1 and 2. Control experiments testing retrieval only after ∼34 h, confirmed the consolidating effect of sleep occurring within 17 h after training. © 2017 Vorster and Born; Published by Cold Spring Harbor Laboratory Press.

  16. Development and application of visual support module for remote operator in 3D virtual environment

    International Nuclear Information System (INIS)

    Choi, Kyung Hyun; Cho, Soo Jeong; Yang, Kyung Boo; Bae, Chang Hyun


    In this research, the 3D graphic environment was developed for remote operation, and included the visual support module. The real operation environment was built by employing a experiment robot, and also the identical virtual model was developed. The well-designed virtual models can be used to retrieve the necessary conditions for developing the devices and processes. The integration of 3D virtual models, the experimental operation environment, and the visual support module was used for evaluating the operation efficiency and accuracy by applying different methods such as only monitor image and with visual support module

  17. Emergency Support Function 15: Communication Synchronization during Defense Support of Civil Authorities Operations (United States)


    reconnaissance; detection and monitoring; communications support; aerial reconnaissance; marijuana eradication; linguist support; air and 9/11.34 The public health information management structure, Medical Electronic Disease Surveillance and Intelligence System (MEDSIS), divides...known harm. Additionally, there will not be any compensation or other forms of benefits provided to me for my participation. The only benefit for me

  18. Biotechnology System Facility: Risk Mitigation on Mir (United States)

    Gonda, Steve R., III; Galloway, Steve R.


    NASA is working with its international partners to develop space vehicles and facilities that will give researchers the opportunity to conduct scientific investigations in space. As part of this activity, NASA's Biotechnology Cell Science Program (BCSP) at the Johnson Space Center (JSC) is developing a world-class biotechnology laboratory facility for the International Space Station (ISS). This report describes the BCSP, including the role of the BTS. We identify the purpose and objectives of the BTS and a detailed description of BTS facility design and operational concept, BTS facility and experiment-specific hardware, and scientific investigations conducted in the facility. We identify the objectives, methods, and results of risk mitigation investigations of the effects of microgravity and cosmic radiation on the BTS data acquisition and control system. These results may apply to many other space experiments that use commercial, terrestrial-based data acquisition technology. Another focal point is a description of the end-to-end process of integrating and operating biotechnology experiments on a variety of space vehicles. The identification of lessons learned that can be applied to future biotechnology experiments is an overall theme of the report. We include a brief summary of the science results, but this is not the focus of the report. The report provides some discussion on the successful 130-day tissue engineering experiment performed in BTS on Mir and describes a seminal gene array investigation that identified a set of unique genes that are activated in space.

  19. Collection of Operating and Support Data from Weapon System Support Contracts (United States)


    Major Associate Contractors or Subcontractors: General Electric (engines) Honeywell (auxiliary power unit) Smiths (stores management system...Aircraft Industries Moto Guzzi (engine) Scope of Effort: Northrop Grumman provides comprehensive contractor logistics support for the Hunter UAV, which

  20. Environmental Biotechnology in China (United States)

    Liu, Shuang Jiang; Liu, Lei; Chaudhry, Muhammad Tausif; Wang, Lei; Chen, Ying Guang; Zhou, Qi; Liu, He; Chen, Jian

    Environmental biotechnology has emerged as an important measure to tackle the environmental pollution as China experiences great economic success. Over the past decade, much emphasis has been paid to the following fields in environmental biotechnology: microbial degradation of toxic and organic chemicals, bio-treatment of wastewater, waste recycling. The Chinese researchers have done a lot of work to understand the natural degradation processes for organic and toxic compounds and finally to clean these compounds from polluted environments. For the treatment of wastewater, many new processes were proposed and optimized to meet the more strict effluent standards in China. Finally, more and more attention has been paid to the reuse of discharged wastes. In this chapter we review the development in the above fields.

  1. Biotechnology for renewable chemicals

    DEFF Research Database (Denmark)

    Borodina, Irina; Kildegaard, Kanchana Rueksomtawin; Jensen, Niels Bjerg


    The majority of the industrial organic chemicals are derived from fossil sources. With the oil and gas resources becoming limiting, biotechnology offers a sustainable alternative for production ofchemicals from renewable feedstocks. Yeast is an attractive cell factory forsustainable production...... for the production of non-native 3-hydroxypropionic acid (3HP).3HP can be chemically dehydrated into acrylic acid and thus can serve as a biosustainable building block for acrylate-based products (diapers, acrylic paints, acrylic polymers, etc.)...

  2. Biotechnology in maize breeding

    Directory of Open Access Journals (Sweden)

    Mladenović-Drinić Snežana


    Full Text Available Maize is one of the most important economic crops and the best studied and most tractable genetic system among monocots. The development of biotechnology has led to a great increase in our knowledge of maize genetics and understanding of the structure and behaviour of maize genomes. Conventional breeding practices can now be complemented by a number of new and powerful techniques. Some of these often referred to as molecular methods, enable scientists to see the layout of the entire genome of any organism and to select plants with preferred characteristics by "reading" at the molecular level, saving precious time and resources. DNA markers have provided valuable tools in various analyses ranging from phylogenetic analysis to the positional cloning of genes. Application of molecular markers for genetic studies of maize include: assessment of genetic variability and characterization of germ plasm, identification and fingerprinting of genotypes, estimation of genetic distance, detection of monogamic and quantitative trait loci, marker assisted selection, identification of sequence of useful candidate genes, etc. The development of high-density molecular maps which has been facilitated by PCR-based markers, have made the mapping and tagging of almost any trait possible and serve as bases for marker assisted selection. Sequencing of maize genomes would help to elucidate gene function, gene regulation and their expression. Modern biotechnology also includes an array of tools for introducing or deieting a particular gene or genes to produce plants with novel traits. Development of informatics and biotechnology are resulted in bioinformatic as well as in expansion of microarrey technique. Modern biotechnologies could complement and improve the efficiency of traditional selection and breeding techniques to enhance agricultural productivity.


    Directory of Open Access Journals (Sweden)

    S. I. Artiukhova


    Full Text Available Summary. The article presents data on the development of technology and qualitative research, bio-products «Healing-1». One of the promising directions in food biotechnology is the development of new integrated starter-based consortia of microorganisms, which have higher activity compared with cultures prepared using pure cultures. So it was interesting studies on the development of new biotechnology and bio-based microbial consortium of lactic acid bacteria. Based on the analysis of biotechnological properties of native cultures created a new consortium of microorganisms containing lactic acid streptococci and bacilli, allowing the maximum extent possible to implement the physiological, biochemical and technological potential of microorganisms. Scientifically substantiated and experimentally developed a new biotechnology production of bioproducts «Healing-1», obtained on the basis of microbial consortium with broad spectrum antimicrobial activity. Experimentally investigated quality parameters of organic food «Healing-1» using a new microbial consortium as freshly prepared and during storage. Found that antagonistic activity of microflora bio «Healing-1» with respect to pathogenic and conditionally pathogenic bacteria, as well as its resistance to substances in the gastrointestinal tract of man is more pronounced compared to bioproducts obtained using a separate starter, members of the microbial consortium. It should be noted a more pronounced synthesis of exopolysaccharides in bioproduct «Healing-1», which leads to increased viscosity of the system and improves the consistency of bio. New bioproducts have good organoleptic characteristics and contain a high number of viable cells of lactic acid bacteria. High stability and survival of lactic acid bacteria during storage. In the study of attacked proteins bioproducts digestive proteinases «in vitro» found that the fermentation of milk microbial consortium increases the digestibility

  4. Theoretical and Experimental Impact Analysis of Decision Support Systems for Advanced MCR Operators

    International Nuclear Information System (INIS)

    Lee, Seung Jun; Seong, Poong Hyun


    Human error is recognized as one of the main causes of nuclear power plant (NPP) accidents, and there have been efforts to reduce and prevent human errors by developing various operator support systems. Before adapting these support systems to actual NPPs, it is necessary to validate their reliability and to evaluate their effect on operator performance. Particularly for safety-critical systems such as NPPs, the validation and evaluation of support systems is as important as the design of good systems. Such evaluations may be carried out through a theoretical modelling or experimentation. The objective of this study is to investigate the effects of decision support systems on operator performance by both theoretical and experimental methods. The target system is an integrated decision support system including four decision support sub-systems. In the results of both the theoretical and experimental evaluations, the decision support systems revealed positive effects, and several trends were observed. (authors)

  5. Safety parameter display system: an operator support system for enhancement of safety in Indian PHWRs

    International Nuclear Information System (INIS)

    Subramaniam, K.; Biswas, T.


    Ensuring operational safety in nuclear power plants is important as operator errors are observed to contribute significantly to the occurrence of accidents. Computerized operator support systems, which process and structure information, can help operators during both normal and transient conditions, and thereby enhance safety and aid effective response to emergency conditions. An important operator aid being developed and described in this paper, is the safety parameter display system (SPDS). The SPDS is an event-independent, symptom-based operator aid for safety monitoring. Knowledge-based systems can provide operators with an improved quality of information. An information processing model of a knowledge based operator support system (KBOSS) developed for emergency conditions using an expert system shell is also presented. The paper concludes with a discussion of the design issues involved in the use of a knowledge based systems for real time safety monitoring and fault diagnosis. (author). 8 refs., 4 figs., 1 tab

  6. Practicing environmental biotechnology

    Directory of Open Access Journals (Sweden)

    Bruce E.Rittmann


    Full Text Available Environmental biotechnology involves ″managing microbial communities to provide services to society″.Its success comes from partnering with prokaryotic microorganisms,whose wideranging metabolic capabilities can be harnessed to destroy pollutants and to generate renewable materials.Partnering with microorganisms requires that we understand them well,and important advances in molecular microbial ecology,analytical chemistry,and mathematical modeling are making it possible to look inside the black box of microbial communities.Also crucial is translating the understanding to biotechnological processes that ″work for the microorganisms so that they work for us″.Successful translation demands novel reactor designs,application of advanced materials,and partnering with practitioners and users.The Swette Center for Environmental Biotechnology,founded in at Arizona State University in 2005,brings together the science and engineering tools in an interdisciplinary environment.The Center emphasizes teamwork and collaborations with research and practice partners around the world.Three new technologies illustrate how the Center applies these principles to ″work for the microorganisms″:the H2-based membrane biofilm reactor (MBfR for reducing many oxidized contaminants in water,the microbial electrochemical cells (MXCs for converting organic wastes into renewable products,and Intimately Coupled PhotoBioCatalysis (ICPBC to detoxify very difficult to biodegrade organic pollutants.

  7. Biotechnology in soybean breeding

    Directory of Open Access Journals (Sweden)

    Sudarić Aleksandra


    Full Text Available Biotechnology can be defined broadly as a set of tools that allows scientists to genetically characterize or improve living organisms. Several emerging technologies, such as molecular characterization and genetic transformation, are already being used extensively for the purpose of plant improvement. Other emerging sciences, including genomics and proteomics, are also starting to impact plant improvement. Tools provided by biotechnology will not replace classical breeding methods, but rather will help provide new discoveries and contribute to improved nutritional value and yield enhancement through greater resistance to disease, herbicides and abiotic factors. In soybeans, biotechnology has and will continue to play a valuable role in public and private soybean breeding programs. Based on the availability and combination of conventional and molecular technologies, a substantial increase in the rate of genetic gain for economically important soybean traits can be predicted in the next decade. In this paper, a short review of technologies for molecular markers analysis in soybean is given as well as achievements in the area of genetic transformation in soybean.

  8. Cost and Operational Effectiveness Analysis of Aiternative Force Structures for Fulfillment of the United States Marine Corps Operational Support Airlift and Search and Rescue Missions

    National Research Council Canada - National Science Library

    Chase, Eric


    This thesis provides a preliminary cost and operational effectiveness analysis of alternative force structures for the United States Marine Corps operational support airlift and search and rescue missions...

  9. Knowledge-based support for design and operational use of human-machine interfaces

    International Nuclear Information System (INIS)

    Johannsen, G.


    The possibilities for knowledge support of different human user classes, namely operators, operational engineers and designers of human-machine interfaces, are discussed. Several human-machine interface functionalities are briefly explained. The paper deals with such questions as which type of knowledge is needed for design and operation, how to represent it, where to get it from, how to process it, and how to consider and use it. The relationships between design and operational use are thereby emphasised. (author)

  10. Construction Biotechnology: a new area of biotechnological research and applications. (United States)

    Stabnikov, Viktor; Ivanov, Volodymyr; Chu, Jian


    A new scientific and engineering discipline, Construction Biotechnology, is developing exponentially during the last decade. The major directions of this discipline are selection of microorganisms and development of the microbially-mediated construction processes and biotechnologies for the production of construction biomaterials. The products of construction biotechnologies are low cost, sustainable, and environmentally friendly microbial biocements and biogrouts for the construction ground improvement. The microbial polysaccharides are used as admixtures for cement. Microbially produced biodegradable bioplastics can be used for the temporarily constructions. The bioagents that are used in construction biotechnologies are either pure or enrichment cultures of microorganisms or activated indigenous microorganisms of soil. The applications of microorganisms in the construction processes are bioaggregation, biocementation, bioclogging, and biodesaturation of soil. The biotechnologically produced construction materials and the microbially-mediated construction technologies have a lot of advantages in comparison with the conventional construction materials and processes. Proper practical implementations of construction biotechnologies could give significant economic and environmental benefits.

  11. Biotechnology worldwide and the 'European Biotechnology Thematic Network' Association (EBTNA). (United States)

    Bruschi, F; Dundar, M; Gahan, P B; Gartland, K; Szente, M; Viola-Magni, M P; Akbarova, Y


    The European Biotechnology Congress 2011 held under the auspices of the European Biotechnology Thematic Network Association (EBTNA) in conjunction with the Turkish Medical Genetics Association brings together a broad spectrum of biotechnologists from around the world. The subsequent abstracts indicate the manner in which biotechnology has permeated all aspects of research from the basic sciences through to small and medium enterprises and major industries. The brief statements before the presentation of the abstracts aim to introduce not only Biotechnology in general and its importance around the world, but also the European Biotechnology Thematic Network Association and its aims especially within the framework of education and ethics in biotechnology. Copyright © 2011 Elsevier Ltd. All rights reserved.

  12. "Othering" agricultural biotechnology: Slovenian media representation of agricultural biotechnology. (United States)

    Zajc, Jožica; Erjavec, Karmen


    While studies on media representations of agricultural biotechnology mostly analyse media texts, this work is intended to fill a research gap with an analysis of journalistic interpretations of media representations. The purpose of this project was to determine how news media represent agricultural biotechnology and how journalists interpret their own representations. A content and critical discourse analysis of news texts published in the Slovenian media over two years and in-depth interviews with their authors were conducted. News texts results suggest that most of the news posts were "othering" biotechnology and biotechnologists: biotechnology as a science and individual scientists are represented as "they," who are socially irresponsible, ignorant, arrogant, and "our" enemies who produce unnatural processes and work for biotechnology companies, whose greed is destroying people, animals, and the environment. Most journalists consider these representations to be objective because they have published the biotechnologists' opinions, despite their own negative attitudes towards biotechnology.

  13. Biotechnology: reality or dream

    Directory of Open Access Journals (Sweden)

    Konstantinov Kosana


    Full Text Available The development of molecular biology and molecular genetics, especially of the recombinant DNA technology enabled improvement of experimental methods that provide manipulation within a cell-free system, such as cell and tissue cultures. Such methods resulted in the development of different new technologies with specific properties in relation to the conventional definitions. According to PERSLEY and lantin (2000 the following components are essential for the contemporary biotechnology: (i genomics - a molecular characterization of all genes and gene products of an organism (ii bioinformatics - the assembly of data from genomic analysis into accessible forms; (iii transformation - the introduction of genes controlling a trait of interest into a genome of a desired organism (micro organisms, plants, animal systems. By the application of cotemporary biotechnology new methods in the field of diagnostic are developed such as rapid and more accurate identification of the presence and absence of genes in the genome of the organism of interest (identification of pathogens prenatal diagnostics, molecular markers assisted breeding for plants, etc. The traits of an organism are determined by its genetic material, i.e. by a molecule of deoxyribonucleic acid (DNA. watson and crick (1953 were the first scientists to describe the structure of DNA as a double-stranded helix. Higher organisms contain a set of linear DNA molecules - chromosomes and a full set of chromosomes of an organism is a genome. Each genome is divided into a series of functional units, i.e. genes. The traits of an organism depend on genes, but their expression depends not only on genes but also on many other factors, including whether a gene, controlling the trait, expresses, specific cells in which it expresses and specially the mode by which the gene and its product interact with the environment. A special aspect within the application of biotechnology occurs as an interaction of a

  14. Present status and practical insufficiencies of operator support systems for nuclear power plant. Proposal of an innovative methodology of supporting operators

    International Nuclear Information System (INIS)

    Takano, Kenichi; Sasou, Kunihide


    Intensive literature survey has been done on present status of the Operator Support Systems (OSSs) developed for Nuclear Power Plants (NPPs). As a result, it was clarified that there were some technical insufficiencies on supporting operators' assessment of current situation when his encountering an anomaly occurred at NPPs. To overcome the insufficiencies, newly developed 'Mental Model' methodology recognized as a 'Cognitive Simulator' and used in the operator behavior model 'SYBORG', seemed to be applicable. Consequently, it could be evaluated that this methodology had a technical potential to cover the present insufficiencies and also contribute to ideal systems positively. As the OSSs were developed intensively around 1990, their advancement to practical uses came to a standstill because of their less innovation in methodology. They could be classified roughly to supporting tasks, operational procedure domains, cognitive functions and possible plant transient routes, whose merits and demerits were summarized. And, it was suggested that they had functional insufficiencies in advising operations associated with possible scenarios of anticipated plant revolution. By using newly developed SYBORG, the mental model methodology could make a distinct prediction of near future plant revolution in coping with anomalies form the beginning of the events. (G.K.)

  15. Information Operations - Analysis Support and Capability Requirements (Operations d'information - Soutien a l'analyse et exigences de capacites) (CD-ROM)

    National Research Council Canada - National Science Library


    ...: The focus of the study "Information Operations - Analysis Support and Capability Requirements" undertaken by the RTO Task Group SAS-057 was to provide recommendations to improve analysis support...

  16. Biotechnology and bioeconomy in China. (United States)

    Li, Qing; Zhao, Qinghua; Hu, Yihong; Wang, Hongguang


    From the review of the achievements and advantages in the development of biotechnology (BT) and bioindustry in China, it is clear that the bioeconomy would provide a tremendous opportunity for China to develop sustainably or even surpass a few developed countries. A long-term vision has been made to guide the research and development and industrialization of BT in China. This review detailed the strategies, targets, priorities, and key technologies in each stage. Furthermore, the reviewers expatiated on the establishment of the favorable policies, the foundation of the professional groups, the establishment of the advanced laboratories or centers, the investment mechanisms, the development and evaluation of biosafety, the encouragement and support for the international collaborations and exchanges, and the establishment of the general organizational structure.

  17. Hardware enabled performance counters with support for operating system context switching (United States)

    Salapura, Valentina; Wisniewski, Robert W.


    A device for supporting hardware enabled performance counters with support for context switching include a plurality of performance counters operable to collect information associated with one or more computer system related activities, a first register operable to store a memory address, a second register operable to store a mode indication, and a state machine operable to read the second register and cause the plurality of performance counters to copy the information to memory area indicated by the memory address based on the mode indication.

  18. Development of OSSA(Operation Service Support Agreement) Simulator and Site Acceptance Test

    Energy Technology Data Exchange (ETDEWEB)

    Park, DaeSeung; Ahn, Sung-Jin; Lee, Jong-Beom [KHNP CRI, Daejeon (Korea, Republic of)


    Building the nuclear power plant is on the schedule, remaining question is who could operate the NPP after the construction is finished. OSSA is known as Operation Service Support Agreement, it is the contract between KHNP(Korea Hydro and Nuclear Power Co.,) and ENEC(Emirates Nuclear Energy Corporation) for United Arab Emirates Nuclear Power Plant operations support. The contract is mostly about the safety and reliability operations and as well as of the training of UAE operators to have better experiences. UAE operators needed to be trained and tested before they come to UAE for operate the NPP. The OSSA simulator was built because operator shall not make any mistakes even if the plant is not yet constructed. Simulator Training is a key for getting experiences without operating the actual plant, because the nuclear power plant never used as the test in real situations. Operators’ requirement is to have more than 2 years at site experiences and also they have to be trained 5 to 8 months of the training. The experience such as the site acceptance test will lead the future nuclear industry to meet the global standard and to lead the safety of the NPP. Under the OSSA agreement 400 KHNP experts will support the operations. Most of the operators were trained at the OSSA simulator which is most reliable simulator that can demonstrate satisfactory performance for the simulator.

  19. Controls Over Operating System and Security Software Supporting the Defense Finance and Accounting Service

    National Research Council Canada - National Science Library

    McKinney, Terry


    This is the final in a series of three audits of management controls over the operating systems and security software used by the information processing centers that support the Defense Finance and Accounting Centers (DFAS...

  20. Opportunities for energy conservation through biotechnology

    Energy Technology Data Exchange (ETDEWEB)

    Young, J.K.; Griffin, E.A.; Russell, J.A.


    The purpose of this study is to identify and quantify potential energy savings available through the development and application of biotechnologies. This information is required in support of ECUT research planning efforts as an aid in identifying promising areas needing further consideration and development. It is also intended as background information for a companion ECUT study being conducted by the National Academy of Science to evaluate the use of bioprocessing methods to conserve energy. Several studies have been conducted recently to assess the status and implications of the development of biotechnology. The Office of Technology Assessment (OTA) considered institutional, economic, and scientific problems and barriers. The National Science Foundation sponsored a study to examine regulatory needs for this new and expanding technology. Somewhat in contrast to these studies, this report covers principally the technical issues. It should be emphasized that the practicality of many developments in biotechnology is not evaluated solely on the basis of energy considerations. Bioprocesses must often compete with well-established coal, petroleum, and natural gas technologies. A complete evaluation of the technical, economical, and ecological impacts of the large-scale applications discussed in this report is not possible within the scope of this study. Instead, this report assesses the potential of biotechnology to save energy so that research into all aspects of implementation will be stimulated for those industries with significant energy savings potential. 92 references, 6 figures, 24 tables.

  1. Biotechnology and Consumer Decision-Making. (United States)

    Sax, Joanna K

    Society is facing major challenges in climate change, health care and overall quality of life. Scientific advances to address these areas continue to grow, with overwhelming evidence that the application of highly tested forms of biotechnology is safe and effective. Despite scientific consensus in these areas, consumers appear reluctant to support their use. Research that helps to understand consumer decision-making and the public’s resistance to biotechnologies such as vaccines, fluoridated water programs and genetically engineered food, will provide great social value. This article is forward-thinking in that it suggests that important research in behavioral decision-making, specifically affect and ambiguity, can be used to help consumers make informed choices about major applications of biotechnology. This article highlights some of the most controversial examples: vaccinations, genetically engineered food, rbST treated dairy cows, fluoridated water, and embryonic stem cell research. In many of these areas, consumers perceive the risks as high, but the experts calculate the risks as low. Four major thematic approaches are proposed to create a roadmap for policymakers to consider for policy design and implementation in controversial areas of biotechnology. This article articulates future directions for studies that implement decision-making research to allow consumers to appropriately assign risk to their options and make informed decisions.

  2. Field Artillery And Fire Support At The Operational Level: An Analysis Of Operation Desert Storm and Operation Iraqi Freedom (United States)


    MacArthur’s 1950 Campaign in North Korea,” Historical Perspectives of the Operational Art (Washington, DC: US Army Center of Military History , 2010...Baathist regime. 7 Mary Kaldor, New and Old Wars: Organized Violence in a Global Era, 3d ed...Army, 2002), 12. 20 R. Ernest Dupuy and Trevor N. Dupuy, The Harper Encyclopedia of Military History : From 3500 BC to the Present, 4th Ed. (New York

  3. Computerized operator support system with new man-machine interface for BWR power plants

    International Nuclear Information System (INIS)

    Monta, K.; Naito, N.; Sugawara, M.; Sato, N.; Mori, N.; Tai, I.; Fukumoto, A.; Tsuchida, M.


    Improvement of the man-machine interface of nuclear power plants is an important contribution to the further enhancement of operational safety. In addition, recent advances in computer technology seem to offer the greatest opportunity to date for achieving improvement in the man-machine interface. The development of a computerized operator support system for BWRs has been undertaken since 1980 with the support of the Japanese Government. The conceptual design of this system is based on the role of the operators. The main functions are standby system management, disturbance analysis and post-trip operational guidance. The objective of the standby system management is to monitor the standby status of the engineered safety feature during normal operation to assure its proper functioning at the onset of emergency situations. The disturbance analysis system detects disturbances in the plant in their early stages and informs the plant operators about, for example, the cause of the disturbances, the plant status and possible propagations. Consequently, operators can take corrective actions to prevent unnecessary plant shutdown. The objective of the post trip operational guide is to support operators in diagnosis and corrective action after a plant trip. Its functions are to monitor the performance of the engineered safety feature, to identify the plant status and to guide the appropriate corrective action to achieve safe plant shutdown. The information from the computerized operator support system is supplied to operators through a colour CRT operator console. The authors have evaluated the performance of various new man-machine interfacing tools and proposed a new operator console design. A prototype system has been developed and verification/validation is proceeding with a BWR plant simulator. (author)


    Directory of Open Access Journals (Sweden)

    Z. Jurković


    Full Text Available Research studies in the area of biotechnologies in fruit growing started at the Agricultural Institute Osijek in 2006 with the establishment of the first experimental in vitro laboratory for micropropagation. The laboratory started an active research related to the Project "Biotechnological methods in fruit tree identification, selection and propagation" Project is part of program "Preservation and revitalization of grape and fruit autochthonous cultivars". The goal of this research is to determine genetic differences between autochthonous and introduced cultivars of cherry as well as cultivars and types of sour cherry, to find and optimize a method for fast recovery of clonal material. A great number of cherry cultivars and types within the population of cv. Oblacinska sour cherry exists in Croatia. A survey with the purpose of selecting autochthonous cultivars for further selection has been done in previous research. Differences have been found in a number of important agronomic traits within the populations of cv. Oblačinska sour cherry. Autochthonous cherry cultivars are suspected to be synonyms of known old cultivars which were introduced randomly and have been naturalized under a local name. Identification and description of cultivars and types of fruits is based on special visible properties which were measurable or notable. In this approach difficulties arise from the effect of non-genetic factors on expression of certain traits. Genetic-physiological problem of S allele autoincompatibility exists within cherry cultivars. Therefore it is necessary to put different cultivars in the plantation to pollinate each other. Apart form the fast and certain sort identification independent of environmental factors, biotechnological methods based on PCR enable faster virus detection compared with classical serologic methods and indexing and cover a wider range of plant pathogens including those undetectable by other methods. Thermotherapy and

  5. A Systems Approach to Architecting a Mission Package for LCS Support of Amphibious Operations (United States)


    ESG expeditionary strike group F2T2EA find, fix, track, target, engage, and assess FAA functional area analysis FLIR forward-looking infrared FO...engagement capability. The LCS operating in support of a CSG or expeditionary strike group ( ESG ), or as part of a surface action group (SAG), will...Module 15 2. Anti-Submarine Warfare Mission Package Operating in direct support of a CSG or ESG , or as part of a forward-deployed group, the LCS

  6. Novel oscillatory flow reactors for biotechnological applications


    Reis, N.


    Tese de Doutoramento em Engenharia Química e Biológica This thesis explores the biotechnological applications of two novel scale-down oscillatory flow reactors (OFRs). A micro-bioreactor (working mostly in batch) and a continuous meso-reactor systems were developed based on a 4.4 mm internal diameter tube with smooth periodic constrictions (SPC), both operating under oscillatory flow mixing (OFM). The first part is dedicated to the flow characterisation in the novel SPC geom...

  7. Decision support systems for transportation system management and operations (TSM&O). (United States)


    There is a need for the development of tools and methods to support off-line and real-time : planning and operation decisions associated with the Transportation System Management and : Operations (TSM&O) program. The goal of this proposed project is ...

  8. A decision support system for quayside operations in a container terminal

    NARCIS (Netherlands)

    Ursavas, Evrim


    This paper proposes a decision support system for optimizing operations on the quayside of a container terminal. Due to the existence of multiple parties involved in the decision making processes within port operations, it is essential to pay attention to each parties' concerns and demands which by

  9. Analysis characteristics determination of electrohydraulic control system operation to reduce the operation time of a powered roof support (United States)

    Szurgacz, Dawid


    The article discusses basic functions of a powered roof support in a longwall unit. The support function is to provide safety by protecting mine workings against uncontrolled falling of rocks. The subject of the research includes the measures to shorten the time of roof support shifting. The roof support is adapted to transfer, in hazard conditions of rock mass tremors, dynamic loads caused by mining exploitation. The article presents preliminary research results on the time reduction of the unit advance to increase the extraction process and thus reduce operating costs. Conducted stand tests showed the ability to increase the flow for 3/2-way valve cartridges. The level of fluid flowing through the cartridges is adequate to control individual actuators.

  10. On the article of V. A. Mashin 'Computerized systems of NPP operators support. (Psychological problems)'

    International Nuclear Information System (INIS)

    Prushinskij, B.Ya.


    Basic aspects of V.A. Mashin's article on NPP operator support computerized systems and problems of man-machine interrelation are analyzed. Sharing in the significant degree Mashin's point of view the author of this article considers that the most important aspects of this problem consist in dividing the responsibility for NPP safe operation between all participants of the NPP creation and operation and in the area of practical experience in assuring control functions reliability

  11. Concepts in Biotechnology An Affordable Overview of Biotechnology ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 2; Issue 9. Concepts in Biotechnology An Affordable Overview of Biotechnology Through Self Study and Open Learning Graduates. Narayan S Punekar. Book Review Volume 2 Issue 9 September 1997 pp 77-78 ...

  12. Operator support system for power unit control in abnormal modes of operation

    International Nuclear Information System (INIS)

    Kurka, J.


    I and C system technology, partly Soviet and partly Czechoslovakian, used on the NPP Dukovany units represents the control technology standard of late 70-ties and it becomes the weak part of the whole system. The modernization of the system, therefore, is necessary and it is already in preparation. The specification of both the scope and the depth of upgrading/replacement is being carried out within the framework of the PHARE program. The second phase of the program aimed at the final specifications of requirements on new I and C system is in progress. The output will serve as detailed specification for bid invitation for control system supplier. Parallely, the preparation of specification for WWER-440 full-scope plant simulator for operator training is in progress as well. In the case of two units with WWER-1000 MW reactors, the completion of construction of which was even threaten for a certain period of time, essential changes have taken place in the design of both the I and C systems and the reactor core. 7 figs

  13. Workflow Driven Decision Support Systems : A case of an intra-operative visualization system for surgeons

    NARCIS (Netherlands)

    Jalote-Parmar, A.


    Inadequate visualization during Minimally Invasive Surgeries (MIS) has led several technology research labs to develop decision support systems such as Intra-operative Visualization Systems (IVS). IVS focuses on providing surgeons with real-time imaging support to improve task visualization and

  14. Self-Operated Auditory Prompting Systems: Creating and Using Them to Support Students with Disabilities (United States)

    Savage, Melissa N.


    Some students with disabilities develop a dependence on others for support and can benefit from self-management strategies to increase independence. Self-operated auditory prompting systems are an effective self-management intervention used to increase independence for students with disabilities while continuing to provide the support that they…

  15. Human Behavior and Performance Support for ISS Operations and Astronaut Selections: NASA Operational Psychology for Six-Crew Operations (United States)

    VanderArk, Steve; Sipes, Walter; Holland, Albert; Cockrell, Gabrielle


    The Behavioral Health and Performance group at NASA Johnson Space Center provides psychological support services and behavioral health monitoring for ISS astronauts and their families. The ISS began as an austere outpost with minimal comforts of home and minimal communication capabilities with family, friends, and colleagues outside of the Mission Control Center. Since 1998, the work of international partners involved in the Space Flight Human Behavior and Performance Working Group has prepared high-level requirements for behavioral monitoring and support. The "buffet" of services from which crewmembers can choose has increased substantially. Through the process of development, implementation, reviewing effectiveness and modifying as needed, the NASA and Wyle team have proven successful in managing the psychological health and well being of the crews and families with which they work. Increasing the crew size from three to six brought additional challenges. For the first time, all partners had to collaborate at the planning and implementation level, and the U.S. served as mentor to extrapolate their experiences to the others. Parity in available resources, upmass, and stowage had to be worked out. Steady progress was made in improving off-hours living and making provisions for new technologies within a system that has difficulty moving quickly on certifications. In some respect, the BHP support team fell victim to its previous successes. With increasing numbers of crewmembers in training, requests to engage our services spiraled upward. With finite people and funds, a cap had to placed on many services to ensure that parity could be maintained. The evolution of NASA BHP services as the ISS progressed from three- to six-crew composition will be reviewed, and future challenges that may be encountered as the ISS matures in its assembly-complete state will be discussed.

  16. Development of biotechnology in India. (United States)

    Ghose, T K; Bisaria, V S


    India has embarked upon a very ambitious program in biotechnology with a view to harnessing its available human and unlimited biodiversity resources. It has mainly been a government sponsored effort with very little private industry participation in investment. The Department of Biotechnology (DBT) established under the Ministry of Science and Technology in 1986 was the major instrument of action to bring together most talents, material resources, and budgetary provisions. It began sponsoring research in molecular biology, agricultural and medical sciences, plant and animal tissue culture, biofertilizers and biopesticides, environment, human genetics, microbial technology, and bioprocess engineering, etc. The establishment of a number of world class bioscience research institutes and provision of large research grants to some existing universities helped in developing specialized centres of biotechnology. Besides DBT, the Department of Science & Technology (DST), also under the Ministry of S&T, sponsors research at universities working in the basic areas of life sciences. Ministry of Education's most pioneering effort was instrumental in the creation of Biochemical Engineering Research Centre at IIT Delhi with substantial assistance from the Swiss Federal Institute of Technology, Zurich, Switzerland to make available state-of-the-art infrastructure for education, training, and research in biochemical engineering and biotechnology in 1974. This initiative catalysed biotechnology training and research at many institutions a few years later. With a brief introduction, the major thrust areas of biotechnology development in India have been reviewed in this India Paper which include education and training, agricultural biotechnology, biofertilizers and biopesticides, tissue culture for tree and woody species, medicinal and aromatic plants, biodiversity conservation and environment, vaccine development, animal, aquaculture, seri and food biotechnology, microbial

  17. Biotechnology Towards Energy Crops. (United States)

    Margaritopoulou, Theoni; Roka, Loukia; Alexopoulou, Efi; Christou, Myrsini; Rigas, Stamatis; Haralampidis, Kosmas; Milioni, Dimitra


    New crops are gradually establishing along with cultivation systems to reduce reliance on depleting fossil fuel reserves and sustain better adaptation to climate change. These biological assets could be efficiently exploited as bioenergy feedstocks. Bioenergy crops are versatile renewable sources with the potential to alternatively contribute on a daily basis towards the coverage of modern society's energy demands. Biotechnology may facilitate the breeding of elite energy crop genotypes, better suited for bio-processing and subsequent use that will improve efficiency, further reduce costs, and enhance the environmental benefits of biofuels. Innovative molecular techniques may improve a broad range of important features including biomass yield, product quality and resistance to biotic factors like pests or microbial diseases or environmental cues such as drought, salinity, freezing injury or heat shock. The current review intends to assess the capacity of biotechnological applications to develop a beneficial bioenergy pipeline extending from feedstock development to sustainable biofuel production and provide examples of the current state of the art on future energy crops.

  18. Forest biotechnology and environment

    Energy Technology Data Exchange (ETDEWEB)

    Kopriva, S.; Rennenberg, H. [Freiburg Univ. (Germany). Inst. fuer Forstbotanik und Baumphysiologie


    Forest biotechnology is a relatively young area of applied plant molecular biology that presently concentrates on (i) manipulation of lignin content and composition, (ii) pathogen-, pesticide-, and stress resistance, and (iii) improvement of growth. Transgenic trees have a great potential also in other areas of applied and environmental research, e.g. in the production of phytochemicals and in phytoremediation of polluted soils. To implement the use of biotechnology for these and other purposes improvement of the acceptance in public of genetic engineering general, and the application of transgenic technologies to trees species in particular, is essential. (orig.) [German] Bei der forstlichen Biotechnologie handelt es sich um ein vergleichsweise junges Gebiet der angewandten pflanzlichen Molekularbiologie, das sich derzeit auf folgende Fragestellungen konzentriert: (a) Manipulation des Ligningehalts und der Lignin-Zusammensetzung; (b) Verbesserung der Resistenz gegenueber Pathogenen, Pestiziden und verschiedenen Formen von Stress; (c) Verbesserung des Wachstums. Transgene Baeume haben darueber hinaus ein grosses Potential fuer andere Gebiete der angewandten Forschung und der Umweltforschung, so z.B. fuer die Produktion pflanzlicher Naturstoffe und die Phytosanierung belasteter Boeden. Um die Verwendung biotechnologischer Verfahren fuer diese und andere Zwecke zu implementieren, ist es dringend erforderlich, die Akzeptanz von 'genetic engineering' im allgemeinen und den Einsatz von Technologien zur Herstellung transgener Baeume im besonderen in der Oeffentlichkeit zu verbessern. (orig.)

  19. How can developing countries harness biotechnology to improve health?

    Directory of Open Access Journals (Sweden)

    Persad Deepa L


    Full Text Available Abstract Background The benefits of genomics and biotechnology are concentrated primarily in the industrialized world, while their potential to combat neglected diseases in the developing world has been largely untapped. Without building developing world biotechnology capacity to address local health needs, this disparity will only intensify. To assess the potential of genomics to address health needs in the developing world, the McLaughlin-Rotman Centre for Global Health, along with local partners, organized five courses on Genomics and Public Health Policy in the developing world. The overall objective of the courses was to collectively explore how to best harness genomics to improve health in each region. This article presents and analyzes the recommendations from all five courses. Discussion In this paper we analyze recommendations from 232 developing world experts from 58 countries who sought to answer how best to harness biotechnology to improve health in their regions. We divide their recommendations into four categories: science; finance; ethics, society and culture; and politics. Summary The Courses' recommendations can be summarized across the four categories listed above: Science - Collaborate through national, regional, and international networks - Survey and build capacity based on proven models through education, training, and needs assessments Finance - Develop regulatory and intellectual property frameworks for commercialization of biotechnology - Enhance funding and affordability of biotechnology - Improve the academic-industry interface and the role of small and medium enterprise Ethics, Society, Culture - Develop public engagement strategies to inform and educate the public about developments in genomics and biotechnology - Develop capacity to address ethical, social and cultural issues - Improve accessibility and equity Politics - Strengthen understanding, leadership and support at the political level for biotechnology

  20. A decision support system for identifying abnormal operating procedures in a nuclear power plant

    International Nuclear Information System (INIS)

    Hsieh, Min-Han; Hwang, Sheue-Ling; Liu, Kang-Hong; Liang, Sheau-Farn Max; Chuang, Chang-Fu


    Highlights: ► A decision support system has been constructed and verified. ► The operator's decision-making time was decreased by about 25%. ► The accuracy was increased by about 18%. ► The system prevents overlooking important information. ► Fewer erroneous solutions were implemented, and the mental workload was reduced. - Abstract: In order to prevent safety hazards that can result from inappropriate decisions made by the operators of a nuclear power plant (NPP), this study was undertaken to develop a decision support system to reduce the complexity of the decision-making process by aiding operators’ cognitive activities, integrating unusual symptoms, and identifying the most suitable abnormal operating procedure (AOP) for operators. The study was conducted from the perspective of human factors engineering in order to compare the process that operators originally used to select an AOP with a process that included a support system for AOP identification. The results of the study indicated that the existence of a support system reduces errors by quickly suggesting likely AOPs. With such a support system in place, there were clear improvements in human performance, i.e., decision-making time decreased by about 25%, and the accuracy of the operators’ decisions, judged by the successful resolution of specific problems, increased by about 18%. In addition, there were fewer erroneous solutions implemented, and the mental workload was reduced. Hence, the decision support system is proposed as a training tool in identifying AOPs in the main control room (MCR).

  1. Biotechnology, genetic conservation and sustainable use of ...

    African Journals Online (AJOL)

    ... agriculture, silviculture, horticulture, environment and other important issues. This paper reviews some biotechnological tools that could be harnessed in promoting conservation and sustainable use of bioresources. Key words: Bioresources, genetic conservation, biotechnology. African Journal of Biotechnology Vol. 2 (12) ...

  2. Fostering biotechnology entrepreneurship in developing countries

    African Journals Online (AJOL)


    the growing science base, biotechnology companies can successfully be located and thrive in these countries. The rewards which can flow from the successful exploitation of research should encourage investment in biotechnological activities. Key words: Entrepreneur, biotechnology, investment. INTRODUCTION.

  3. Department of Biotechnology | Women in Science | Initiatives ...

    Indian Academy of Sciences (India)

    Department of Biotechnology. Department of Biotechnology Awards; National Woman Bioscientist Awards; Biotech Product & Process Development & Commercialization Awards; Awardees of National Bioscience Awards for Career Development. Department of Biotechnology Awardees. Year: 2012 Innovative Young ...

  4. Environmental biotechnology: concepts and applications

    National Research Council Canada - National Science Library

    Winter, Josef; Jördening, Hans-Joachim


    ... for the - development of new and environmentally improved production technologies with less purified substrates and generation of fewer by-products - bioproducts as non-toxic matters, mostly recyclable. Some impressive studies on industrial applications of biotechnology are published in two OECD reports, which summarized, that biotechnology has the potential o...

  5. A Case for Teaching Biotechnology (United States)

    Lazaros, Edward; Embree, Caleb


    Biotechnology is an innovative field that is consistently growing in popularity. It is important that students are taught about this technology at an early age, so they are motivated to join the field, or at least motivated to become informed citizens and consumers (Gonzalez, et al, 2013). An increase in biotechnology knowledge can result in an…

  6. Teachers' Concerns about Biotechnology Education (United States)

    Borgerding, Lisa A.; Sadler, Troy D.; Koroly, Mary Jo


    The impacts of biotechnology are found in nearly all sectors of society from health care and food products to environmental issues and energy sources. Despite the significance of biotechnology within the sciences, it has not become a prominent trend in science education. In this study, we seek to more fully identify biology teachers' concerns…

  7. Preface: Biocatalysis and Agricultural Biotechnology (United States)

    This book was assembled with the intent of bringing together current advances and in-depth reviews of biocatalysis and agricultural biotechnology with emphasis on bio-based products and agricultural biotechnology. Recent energy and food crises point out the importance of bio-based products from ren...

  8. Biotechnology Outlines for Classroom Use. (United States)

    Paolella, Mary Jane


    Presents a course outline for the study of biotechnology at the high school or college level. The outline includes definitions, a history, and the vocabulary of biotechnology. Presents a science experiment to analyze the effects of restriction enzymes on DNA. (MDH)

  9. A logic flowgraph-based concept for decision support and management of nuclear plant operation

    International Nuclear Information System (INIS)

    Guarro, S.B.


    The architecture of an automated decision support system for nuclear plant operators is presented and discussed. The system is based on the use of 'logic flowgraph' process models and is designed in a hierarchical fashion. Its functionality spans from 'function oriented' plant status and alternative success path information displayed to the plant operators at its higher access levels to 'process oriented' diagnostic and recovery information deduced and displayed at its lowest. The design basis for this architecture is the 'defense in depth' plant safety concept. The decision support system goal is to provide plant operators, in the presence of an unforeseen transient, with the best and safest alternative between plant stabilization after shutdown and recovery of normal operation based on early diagnosis. Examples of the system capability to interpret and diagnose abnormal plant conditions and of the information that it can supply to the operators at its three access levels are presented and discussed. (author)

  10. Agenda 21: biotechnology at the United Nations Conference on Environment and Development. (United States)

    Taylhardat, A R; Zilinskas, R A


    Preparation has yet to be completed for the 1992 Earth Summit, UN Conference on Environment and Development (UNCED), in Rio de Janeiro, Brazil. Nonetheless, it has been planned as a forum in which recommendations will be made to governments and international organizations on how to alleviate environmental damage caused by human activities and how to prevent future damage without retarding development in the Third World. It will declare basic principles for national and individual conduct regarding environmental preservation and sustainable development; adopt international conventions to protect biodiversity and manage climatic change; lay out Agenda 21 activities as specified by UNCED; provide an agenda to help Third World governments manage environmental matters; and provide an agenda for improving the transfer of technology to developing countries. Where biotechnology is concerned, scientists and policy makers in developing countries have shown their interest. Limited resources and capabilities, however, constrain their abilities to engage in serious research and development. International organizations such as the UN Industrial Development Organization (UNIDO) may help UNCED and developing countries with biotechnology. Since 1986, UNIDO has held the International Centre for Genetic Engineering and Biotechnology (ICGEB) as a special project. The ICGEB conducts research and development (R&D) on high priority topics in developing countries; trains scientific and technical personnel from member countries in advanced biotechnology techniques; helps member countries implement and operate ICGEB-affiliated R&D and training centers; and manages an information exchange for internationally affiliated centers. To maximize the potential of biotechnology to help Third World nations clear their environments of pollutants while safely exploiting natural resources, organizations should promote full use of available training resources; promote biosafety and the dissemination of

  11. Egyptian Journal of Biotechnology: Journal Sponsorship

    African Journals Online (AJOL)

    Egyptian Journal of Biotechnology: Journal Sponsorship. Journal Home > About the Journal > Egyptian Journal of Biotechnology: Journal Sponsorship. Log in or Register to get access to full text downloads.

  12. Nigerian Journal of Biotechnology: Journal Sponsorship

    African Journals Online (AJOL)

    Nigerian Journal of Biotechnology: Journal Sponsorship. Journal Home > About the Journal > Nigerian Journal of Biotechnology: Journal Sponsorship. Log in or Register to get access to full text downloads.

  13. Biotechnological advances in Lilium. (United States)

    Bakhshaie, Mehdi; Khosravi, Solmaz; Azadi, Pejman; Bagheri, Hedayat; van Tuyl, Jaap M


    Modern powerful techniques in plant biotechnology have been developed in lilies (Lilium spp., Liliaceae) to propagate, improve and make new phenotypes. Reliable in vitro culture methods are available to multiply lilies rapidly and shorten breeding programs. Lilium is also an ideal model plant to study in vitro pollination and embryo rescue methods. Although lilies are recalcitrant to genetic manipulation, superior genotypes are developed with improved flower colour and form, disease resistance and year round forcing ability. Different DNA molecular markers have been developed for rapid indirect selection, genetic diversity evaluation, mutation detection and construction of Lilium linkage map. Some disease resistance-QTLs are already mapped on the Lilium linkage map. This review presents latest information on in vitro propagation, genetic engineering and molecular advances made in lily.

  14. Knowledge and Attitudes Towards Biotechnology of Elementary Education Preservice Teachers: The first Spanish experience (United States)

    Casanoves, Marina; González, Ángel; Salvadó, Zoel; Haro, Juan; Novo, Maite


    Due to the important impact that biotechnology has on current Western societies, well-informed critical citizens are needed. People prepared to make conscious decisions about aspects of biotechnology that relate to their own lives. Teachers play a central role in all education systems. Thus, the biotechnological literacy of preservice teachers is an important consideration as they will become an influential collective as future teachers of the next generation of children. The attitudes toward science (and biotechnology) that teachers have affect their behavior and influence the way they implement their daily practice of science teaching in school. This study analyzes the attitudes and knowledge of Spanish preservice teachers toward biotechnology. We designed a new survey instrument that was completed by 407 university students who were taking official degree programs in preschool and primary education. Our results point out that although they are aware of biotechnology applications, topics concerning the structure of DNA, management of genetic information inside the cell, genetically modified organism technology and the use of microorganisms as biotechnological tools were not correctly answered. According to our attitude analysis, Spanish preservice teachers could be defined as opponents of genetically modified product acquisition, supporters of biotechnology for medical purposes and highly interested in increasing their knowledge about biotechnology and other scientific advances. Our results show a positive correlation between better knowledge and more positive attitudes toward biotechnology. A Spanish preservice teacher with positive attitudes toward biotechnology tends to be a student with a strong biology background who scored good marks in our knowledge test.

  15. Diversity and consensus as key concepts for design of intelligent operator support system

    International Nuclear Information System (INIS)

    Kitamura, M.; Furukawa, H.; Sakuma, M.; Washio, T.


    A general framework and guiding principles for development of intelligent operator support system in nuclear plants are proposed in this paper. The main principle is to provide advisory information to the operators through consensus of multiple agents each of which can conduct operational decision- making by focusing on mutually dissimilar symptoms obtained from the plant. The applicability and credibility of the operator support system are expected to be significantly improved by implementing the proposed scheme. An efficient procedure for diversifying the symptom descriptions was developed together with a method for autonomous consensus formation among the agents. A prototype system was developed for the subtask of fault diagnosis by emulating multiple neural networks as the diagnostic agents. The advantage of the proposed methodology over the conventional ones was clearly demonstrated through numerical evaluations simulating anomalies in a pressurized water reactor. (author)

  16. Final report on evaluation of cyclocraft support of oil and gas operations in wetland areas

    Energy Technology Data Exchange (ETDEWEB)

    Eggington, W.J.; Stevens, P.M.; John, C.J.; Harder, B.J.; Lindstedt, D.M.


    The cyclocraft is a proven hybrid aircraft, capable of VTOL, lifting heavy and bulky loads, highly controllable, having high safety characteristics and low operating costs. Mission Research Corporation (MRC), under Department of Energy sponsorship, is evaluating the potential use of cyclocraft in the transport of drill rigs, mud, pipes and other materials and equipment, in a cost effective and environmentally safe manner, to support oil and gas drilling, production, and transportation operations in wetland areas. Based upon the results of an earlier parametric study, a cyclocraft design, having a payload capacity of 45 tons and designated H.1 Cyclocraft, was selected for further study, including the preparation of a preliminary design and a development plan, and the determination of operating costs. This report contains all of the results derived from the program to evaluate the use of cyclocraft in the support of oil and gas drilling and production operations in wetland areas.

  17. Emerging Agricultural Biotechnologies for Sustainable Agriculture and Food Security. (United States)

    Anderson, Jennifer A; Gipmans, Martijn; Hurst, Susan; Layton, Raymond; Nehra, Narender; Pickett, John; Shah, Dilip M; Souza, Thiago Lívio P O; Tripathi, Leena


    As global populations continue to increase, agricultural productivity will be challenged to keep pace without overtaxing important environmental resources. A dynamic and integrated approach will be required to solve global food insecurity and position agriculture on a trajectory toward sustainability. Genetically modified (GM) crops enhanced through modern biotechnology represent an important set of tools that can promote sustainable agriculture and improve food security. Several emerging biotechnology approaches were discussed in a recent symposium organized at the 13th IUPAC International Congress of Pesticide Chemistry meeting in San Francisco, CA, USA. This paper summarizes the innovative research and several of the new and emerging technologies within the field of agricultural biotechnology that were presented during the symposium. This discussion highlights how agricultural biotechnology fits within the context of sustainable agriculture and improved food security and can be used in support of further development and adoption of beneficial GM crops.

  18. PUREX environmental radiological surveillance - preoperational and operational support program conducted by Pacific Northwest Laboratory

    International Nuclear Information System (INIS)

    Sula, M.J.; Price, K.R.


    This report describes the radiological environmental sampling program that is being conducted at the US Department of Energy's (DOE) Hanford Site in support of resumed operation of the PUREX fuel processing plant. The report also summarizes preoperational radiological environmental data collected to date. The activities described herein are part of the ongoing Hanford Environmental Surveillance Program, operated by the Pacific Northwest Laboratory (PNL) for the DOE

  19. MIO Cortex: Memory Mechanisms for Operator-Expert Networked Decision Support (United States)


    knowledge in such networked DSS: – social or organizational memory as exemplified by reach back to subject matter experts – software encoded knowledge...MIO Cortex: Memory Mechanisms for Operator-Expert Networked Decision Support Dr. Alex Bordetsky, Professor Steven Mullins, PhD student 19 Jun...DATE JUN 2013 2. REPORT TYPE 3. DATES COVERED 00-00-2013 to 00-00-2013 4. TITLE AND SUBTITLE MIO Cortex: Memory Mechanisms for Operator-Expert

  20. Novel operational approaches to support medical countmeasure response to radiological or nerve agent events

    International Nuclear Information System (INIS)

    Withcomb, R.; Adams, S.


    Presentation will highlight two unique operational approaches developed by CDC to support the US Governments rapid medical countermeasure response to radiological and nerve agent exposures. Specifically new CDC's DTPA Forward Placement Project and CHEMPACK program will be discussed and contrasted as will the planning efforts necessary to develop an optimized operational approach and integrate each of these countermeasures into a rapid medical response program whose success is dependent on collaboration of both National and local authorities.(author)

  1. A framework for synthesizing the United States Code in support of cyberspace operations


    Stonehouse, Joshua C.


    Approved for public release; distribution is unlimited In recent years, federal agencies and organizations have witnessed their jurisdictions converge in a number of areas that support U.S. national security. For operations that rely heavily upon information technology, the complexity associated with clarifying statutory authority has been met with inconsistent responses. Attempts to comprehend the technological implications of these operations has been accompanied by a shift in seeing the...

  2. Industrial hygiene support of underground operations at the Nevada Test Site

    International Nuclear Information System (INIS)

    Porter, P.F.


    The Industrial Hygiene Section of the Health Protection Department provides industrial hygiene support of underground operations at the Nevada Test Site. This report describes support operations and summarizes the industrial hygiene data collected from July 31, 1989 through June 30, 1991. Air quality data were collected by means of personnel sampling by active and passive techniques using various kinds of industrial hygiene instrumentation and through localized and general area monitoring. The data collected were used to evaluate underground air quality and quantity requirements; evaluate worker exposures to a variety of air contaminants; determine the applicability and effectiveness of personal protective equipment

  3. Issues regarding the design and acceptance of intelligent support systems for reactor operators

    International Nuclear Information System (INIS)

    Bernard, J.A.


    In this paper, factors relevant to the design and acceptance of intelligent support systems for the operation of nuclear power plants are enumerated and discussed. The central premise is that conventional expert systems which encode experiential knowledge in production rules are not a suitable vehicle for the creation of practical operator support systems. The principal difficulty is the need for real-time operation. This in turn means that intelligent support systems will have knowledge bases derived from temporally accurate plant models, inference engines that permit revisions in the search process so as to accommodate revised or new data, and man-machine interfaces that do not require any human input. Such systems will have to be heavily instrumented and the associated knowledge bases will require a hierarchical organization so as to emulate human approaches to analysis. Issues related to operator acceptance of intelligent support tools are then reviewed. Possible applications are described and the relative merits of the machine- and human-centered approaches to the implementation of intelligent support systems are enumerated. The paper concludes with a plea for additional experimental evaluations

  4. Operator decision support system for integrated wastewater management including wastewater treatment plants and receiving water bodies. (United States)

    Kim, Minsoo; Kim, Yejin; Kim, Hyosoo; Piao, Wenhua; Kim, Changwon


    An operator decision support system (ODSS) is proposed to support operators of wastewater treatment plants (WWTPs) in making appropriate decisions. This system accounts for water quality (WQ) variations in WWTP influent and effluent and in the receiving water body (RWB). The proposed system is comprised of two diagnosis modules, three prediction modules, and a scenario-based supporting module (SSM). In the diagnosis modules, the WQs of the influent and effluent WWTP and of the RWB are assessed via multivariate analysis. Three prediction modules based on the k-nearest neighbors (k-NN) method, activated sludge model no. 2d (ASM2d) model, and QUAL2E model are used to forecast WQs for 3 days in advance. To compare various operating alternatives, SSM is applied to test various predetermined operating conditions in terms of overall oxygen transfer coefficient (Kla), waste sludge flow rate (Qw), return sludge flow rate (Qr), and internal recycle flow rate (Qir). In the case of unacceptable total phosphorus (TP), SSM provides appropriate information for the chemical treatment. The constructed ODSS was tested using data collected from Geumho River, which was the RWB, and S WWTP in Daegu City, South Korea. The results demonstrate the capability of the proposed ODSS to provide WWTP operators with more objective qualitative and quantitative assessments of WWTP and RWB WQs. Moreover, the current study shows that ODSS, using data collected from the study area, can be used to identify operational alternatives through SSM at an integrated urban wastewater management level.

  5. Bioceres: AG Biotechnology from Argentina

    Directory of Open Access Journals (Sweden)

    Roberto Feeney


    Full Text Available In this case we present a business decision-making situation in which the CEO of an Argentine Ag Biotech company, Bioceres, has to decide the best way to commercialize a new drought-tolerant transgenic technology. The company was founded by twenty three farmers, who shared a common dream that Argentina could become a benchmark in the development of Ag biotechnology. The case has strategic and financial implications, as well as decision-making situation involving a joint venture with an American biotechnology company. It also introduces to discussion the business models of Ag biotechnology companies in developing countries.


    Directory of Open Access Journals (Sweden)

    Irina Ramona PECINGINĂ


    Full Text Available Biotechnology is the integral application of biological and engineering sciences for the technological use of living organisms, biologically active acellular structures and molecular analogues for the production of goods and services.The role of biotechnology is very important in the food industry; this is a biotechnology because agro-food raw materials are biological products and therefore their conservation until consumption, fresh or industrialization involves the control of the enzymatic activity of the vegetal and animal tissues or of the microflora contamination.

  7. Care Management In The Family Health Support Core: Technologies Operated In The Professional Dimension


    José Maria Ximenes Guimarães; Gerlane Holanda de Freitas; Aretha Feitosa de Araújo; Maria Claudia de Freitas Lima; Élcio Basílio Pereira Machado; Cleide Carneiro; Maria Elidiana de Araújo Gomes; Fernando Luiz Affonso Fonseca; Maria do Socorro Sousa; Myrla Alves de Oliveira; Tatyane Oliveira Rebouças; Eduardo Carvalho de Souza; Ana Maria Araújo Salomão


    Introduction: The Centre for Health Support Family - NASF has a innovative character with potential to concretize change in the organization of services and in care practices, supporting and expanding the solvability of the actions of the teams of the Family Health Strategy - FHS. To this end, it must operationalize technologies, arrangements and care management devices. Objective: To describe the care management technologies, particularly in the professional dimension, operated by the t...

  8. Approximation of Schrodinger operators with delta-interactions supported on hypersurfaces

    Czech Academy of Sciences Publication Activity Database

    Behrndt, J.; Exner, Pavel; Holzmann, M.; Lotoreichik, Vladimir


    Roč. 290, 8-9 (2017), s. 1215-1248 ISSN 0025-584X R&D Projects: GA ČR(CZ) GA14-06818S Institutional support: RVO:61389005 Keywords : Schrodinger operators * delta-interactions supported on hypersurfaces * approximation by scaled regular potentials * norm resolvent convergence * spectral convergence Subject RIV: BE - Theoretical Physics OBOR OECD: Pure mathematics Impact factor: 0.742, year: 2016

  9. Development strategies on an integrated operator decision aid support system for nuclear power plants

    International Nuclear Information System (INIS)

    Ki Sig Kang; Han Gon Kim; Soon Heung Chang; Jeong, Hee Kyo; Park, S.D.


    The development strategies on an integrated operator decision aid support (IODAS) system are discussed by focusing attention on the importance of the operator's role for nuclear power plants. The IODAS is under development to support the operator's decision making process and to enhance the safety of a nuclear power plant by providing the plant operators with timely and proper guideline during abnormal and emergency conditions. The IODAS has capabilities for the signal validation/management, the alarm processing, the failure diagnosis using abnormal operating procedures, and the dynamic tracking of emergency operating procedures using function restoration guidelines and optimal recovery guidelines with a series of complex logic steps covering a broad spectrum of event sequences. The proposed system is being implemented on a SUN-4/75 Workstation using C and Quintus TM prolog language. For verification studies a full-scope real-time simulator is being used. Test results show that the IODAS is capable of diagnosing a plant failure quickly and of providing an operator guideline with fast response time. After verification, the IODAS will be installed in the main control room of the unit one nuclear power plant at Yeoung Gwang

  10. A knowledge based operator support system for emergency conditions in nuclear power plants

    International Nuclear Information System (INIS)

    Venkatesh Babu, C.; Subramanium, K.


    The control centres of the operating Indian nuclear power plants contain a large number of indicators and controls spread over many panels. In the event of onset of an emergency condition, there results a profusion of information, both numeric and symbolic. The operator may succumb to an information and cognitive overload that may be compounded by a lack of knowledge. The failure to apply knowledge and reasoning to solve an operational problem can lead to human error, which has been a major contributing factor in nuclear accidents. From the viewpoint of Artificial Intelligence, human error occurs if the operational problem requires computing resources that exceed human capabilities. The application of Artificial Intelligence, particularly expert systems, to nuclear power plant control room activities has considerable potential to reduce operator error and improve safety and reliability. The purpose of this paper is to discuss an investigative study of the feasibility of developing an operator support system incorporating Artificial Intelligence techniques. An information processing model of such a system, herein designated as Knowledge Based Operator Support System - KBOSS, employing expert systems technology, has been developed. The features of this system are described, and issues involved in its development are discussed. (author). 2 refs., 5 figs., 1 tab

  11. Supporting Biotechnology Regulatory Policy Processes in Southeast ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The idea is to maximize the benefits and minimize the risks of GE crops by strengthening the institutions and organizations involved in their adoption, thereby ... The project will also help build the capacity of research partners, including junior researchers, graduate students and policymakers, in the countries involved.

  12. Operator models for delivering municipal solid waste management services in developing countries: Part B: Decision support. (United States)

    Soós, Reka; Whiteman, Andrew D; Wilson, David C; Briciu, Cosmin; Nürnberger, Sofia; Oelz, Barbara; Gunsilius, Ellen; Schwehn, Ekkehard


    This is the second of two papers reporting the results of a major study considering 'operator models' for municipal solid waste management (MSWM) in emerging and developing countries. Part A documents the evidence base, while Part B presents a four-step decision support system for selecting an appropriate operator model in a particular local situation. Step 1 focuses on understanding local problems and framework conditions; Step 2 on formulating and prioritising local objectives; and Step 3 on assessing capacities and conditions, and thus identifying strengths and weaknesses, which underpin selection of the operator model. Step 4A addresses three generic questions, including public versus private operation, inter-municipal co-operation and integration of services. For steps 1-4A, checklists have been developed as decision support tools. Step 4B helps choose locally appropriate models from an evidence-based set of 42 common operator models ( coms); decision support tools here are a detailed catalogue of the coms, setting out advantages and disadvantages of each, and a decision-making flowchart. The decision-making process is iterative, repeating steps 2-4 as required. The advantages of a more formal process include avoiding pre-selection of a particular com known to and favoured by one decision maker, and also its assistance in identifying the possible weaknesses and aspects to consider in the selection and design of operator models. To make the best of whichever operator models are selected, key issues which need to be addressed include the capacity of the public authority as 'client', management in general and financial management in particular.

  13. Public attitude towards modern biotechnology | Amin | African ...

    African Journals Online (AJOL)

    This article reviews the literature related to the main idea of the study, rooting from the definition of biotechnology, global status of commercialized biotechnology products, and global and local public attitudes towards modern biotechnology and past models for attitude towards modern biotechnology. The first section of the ...

  14. Proceedings of the International Symposium on Biotechnology

    International Nuclear Information System (INIS)


    This is a book of abstracts of oral communications and posters that were presented during the International Symposium on Biotechnology that was held in Sfax, Tunisia from May 4th to 8th, 2008. The following themes were covered : - Biotechnology for animal and human health and biopharmaceuticals; - Microbial and environmental biotechnology; - Agricultural, Food and marine biotechnology

  15. MORS Workshop. Operations Analysis Support to Network Centric Operations. Held in McLean, VA on 27-29 January 2004

    National Research Council Canada - National Science Library

    Ross-Witkowski, Corrina


    As Network Centric Operations (NCO) are being developed, the analytic community is being called upon to support the military services with assessments of needs and capability gaps to support decisions concerning options...

  16. Improvements of MMI and operator support systems at the Leningrad NPP

    International Nuclear Information System (INIS)

    Rakitin, I.D.; Malkin, S.D.; Shalia, V.V.; Fedorov, E.M.; Koudiakov, M.M.; Stebenev, A.S.


    A practical need of MMI up-grade and inclusion of new Operator Support Systems is of utmost importance for the existing NPPs under the new safety related Russian and International demands, requirements and regulations. The given paper describes RandD work for RBMK-type reactors with using full scope simulator features. But its main results could be well implemented for other reactor types as well. Significant efforts to up-grade safety of RBMK and implement a set of additional Safety Support Systems are provided by the Russian Project Design Institutes and by the International Organizations and Communities. But these projects have been mostly developed without a proper verification and validation against the real plant operation modes and real Control Room circumstances, and with no justification of an operating crew demands and expectations. That unfavorable situation should be successfully changed by now with using the Training Support Center (TSC) created at the Leningrad NPP. It incorporates the full-scope and analytical simulators working in parallel with the prototypes of the expert and interactive systems to provide a new scope of RandD work. The development and adjustment of two state-of-the-art Operators' Support Systems with using the Simulators are described in the Paper. These systems have been developed by the joint RRC KI and LNPP team. (author)

  17. Identification of Decision Support Concepts for the Planning of Air Force Immediate Contingencies Operations (United States)


    Cognitive Ergonomics, Madeira , Portugal. * # North American Treaty Organisation (NATO) (2006). Tool for the Operational Planning, Force...User Interaction to Inform Information- Fusion-Driven Decision Support, presented at the European Conference on Cognitive Ergonomics, Madeira , Portugal...Ergonomics, Madeira , Portugal. Pages: 4. Context: This paper intends to extend current paradigms of user driven Information Fusion (IF) by

  18. 007 to the Rescue – Cognitive Fit of Operations Research and Agent-based Decision Support

    NARCIS (Netherlands)

    Krauth, Elfriede I.; van Hillegersberg, Jos; van de Velde, Steef L.


    Adoption rates of traditional Operations Research (OR) based decision support systems (DSS) suffer from perceived complexity of the underlying model and its detrimental effect on user-friendliness. The mental effort required to understand abstract models can hinder adoption. This barrier may seem

  19. Liquid phase methanol LaPorte process development unit: Modification, operation, and support studies

    Energy Technology Data Exchange (ETDEWEB)


    This report consists of Detailed Data Acquisition Sheets for Runs E-6 and E-7 for Task 2.2 of the Modification, Operation, and Support Studies of the Liquid Phase Methanol Laporte Process Development Unit. (Task 2.2: Alternate Catalyst Run E-6 and Catalyst Activity Maintenance Run E-7).

  20. Towards fault-tolerant decision support systems for ship operator guidance

    DEFF Research Database (Denmark)

    Nielsen, Ulrik Dam; Lajic, Zoran; Jensen, Jørgen Juncher


    Fault detection and isolation are very important elements in the design of fault-tolerant decision support systems for ship operator guidance. This study outlines remedies that can be applied for fault diagnosis, when the ship responses are assumed to be linear in the wave excitation. A novel num...

  1. 38 CFR 61.80 - General operation requirements for supportive housing and service centers. (United States)


    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false General operation requirements for supportive housing and service centers. 61.80 Section 61.80 Pensions, Bonuses, and Veterans... assuring safety from fire; (10) All food preparation areas must contain suitable space and equipment to...

  2. Enhanced Situational Awareness and Decision Support for Operators of Future Distributed Power Network Architectures

    DEFF Research Database (Denmark)

    Zaher, Ammar S. A. E.; Catterson, V. M.; Syed, M. H.


    . The control room visualisation and decision support functionality for aiding the operator in restoring the frequency to its target value will be considered. The analysis takes place within the Web-ofCells framework, adopted to deal with power system control through a web of subsystems, called cells, which...

  3. Strong Coupling Asymptotics for a Singular Schrodinger Operator with an Interaction Supported by an Open Arc

    Czech Academy of Sciences Publication Activity Database

    Exner, Pavel; Pankrashkin, K.


    Roč. 39, č. 2 (2014), s. 193-212 ISSN 0360-5302 R&D Projects: GA ČR GAP203/11/0701 Institutional support: RVO:61389005 Keywords : Eigenvalue * Schrödinger operator * singular interaction * strong coupling * 35Q40 * 35P15 * 35J10 Subject RIV: BE - Theoretical Physics Impact factor: 1.013, year: 2014

  4. Improving Command and Control in the Mexican Army and Air Force to Support Land Operations (United States)


    Facilities and Policy FLIR Forward Looking Infrared System FMF Fleet Marine Force FM Field Manual GDP Gross Domestic Product GPS Global market , this thesis will attempt to present optimal solutions to improve Command and Control in support of land operations. Significance of...researched manuals and public documents was considered employing criteria that meets validity, reliability, practicability, suitability and

  5. Year-Round Education: Impact on Support Services, Transportation, Operation, Facilities, and Maintenance. (United States)

    Bradford, James C., Jr.

    This paper presents a case for the implementation of year-round education, arguing that education needs to effectively and efficiently utilize school facilities. The paper focuses on the cost of implementing and operating year-round schools--the impact on support services, transportation, facilities, and maintenance. Data are based on a review of…

  6. Canadian Forces in Joint Fires Support - Human Factors Analysis: Coalition Operations (United States)


    Errors - misinterpretations  Exposure to phonetic pronunciations of STANAG terms and brevity words.  Support voice communications with text...brevity terms, English ) is not sufficient in itself to eliminate language issues which delay timelines, a common understanding of the intended meaning...confusion in coalition operations: (1) differences in the actual language spoken (for example, German vs. English ); (2) differences in the military

  7. Recipe-Based Engineering and Operator Support for Flexible Configuration of High-Mix Assembly

    NARCIS (Netherlands)

    Verhoosel, J.P.C.; Bekkum, M.A. van


    Nowadays, manufacturers must be increasingly flexible to quickly produce a high mix of on-demand, customer-specific, low volume product types. This requires flexible assembly lines with operators that are well-supported in their constantly changing assembly task, while producing high-quality,

  8. Organized network for supporting the amateur-scientist co-operation in Finland (United States)

    Mäkelä, V.; Haukka, H.; Oksanen, A.; Hentunen, V.-P.


    PROAM network is a working group of Ursa Astronomical Association [1] for supporting Finnish amateur astronomers participating to co-operation projects between professional and amateur astronomers. The network relays the information on projects, maintains professional contacts and arranges training on technical skills for research work.

  9. Does the United States’ Strategic Mobility Program Support the Needs of Operational Commanders (United States)


    engineering and humanitarian relief missions conducted by USSOUTHCOM in Cnetral American and the Carribean . 70 Ibid. 25 vessels with two berths of...Does the United States’ Strategic Mobility Program Support the Needs of Operational Commanders? A Monograph by MAJ Erik E. Hilberg United...per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and

  10. Thermal-Hydraulic Analysis Tasks for ANAV NPPs in Support of Plant Operation and Control

    Directory of Open Access Journals (Sweden)

    L. Batet


    Full Text Available Thermal-hydraulic analysis tasks aimed at supporting plant operation and control of nuclear power plants are an important issue for the Asociación Nuclear Ascó-Vandellòs (ANAV. ANAV is the consortium that runs the Ascó power plants (2 units and the Vandellòs-II power plant. The reactors are Westinghouse-design, 3-loop PWRs with an approximate electrical power of 1000 MW. The Technical University of Catalonia (UPC thermal-hydraulic analysis team has jointly worked together with ANAV engineers at different levels in the analysis and improvement of these reactors. This article is an illustration of the usefulness of computational analysis for operational support. The contents presented were operational between 1985 and 2001 and subsequently changed slightly following various organizational adjustments. The paper has two different parts. In the first part, it describes the specific aspects of thermal-hydraulic analysis tasks related to operation and control and, in the second part, it briefly presents the results of three examples of analyses that were performed. All the presented examples are related to actual situations in which the scenarios were studied by analysts using thermal-hydraulic codes and prepared nodalizations. The paper also includes a qualitative evaluation of the benefits obtained by ANAV through thermal-hydraulic analyses aimed at supporting operation and plant control.

  11. Environmental biotechnology for sustainability. (United States)

    Verstraete, W


    In the post-industrial society, waste management is integrated in the concepts of responsibility, reliability and continuity. Therefore industry and public office are obliged to implement the concepts of structured environmental management systems more and more strictly. The endpoints are dependent on the type of wastes and on the priorities set by society. They will with time evolve towards more restriction of all kinds of emissions. This will require increasing inputs of labour, information technology and energy into waste treatment and overall waste management. Particularly for aqueous and gaseous wastes that are not contained, continuously improving treatment with maximum re-use and minimum dissipation in the ecosphere will be the trend of the future. Moreover, the public in general and the individual citizen in particular will request to have (bio)assays to monitor regularly and autonomously the quality of his environment. Such advanced waste management requires considerable energy input. It thus may come in conflict with current concerns about CO2-emissions and the Kyoto agreements. Innovative approaches to combine waste management and the International Climate Change Partnership (ICCP) directives, for instance by implementing biological carbon sequestration, are therefore warranted. Biotechnology has a major role to play particularly in terms of advanced treatment down to ng/l-levels and in terms of validating the quality of the environment by means of powerful and intelligent bio-monitoring devices.

  12. Key points in biotechnological patents to be exploited. (United States)

    García, Alfredo Mateos; López-Moya, José Rafael; Ramos, Patricia


    Patents in some biotechnological fields are controversial. Despite this fact, the number of patent applications increases every year. Total revenues in the global biotechnology market are expected to increase in the middle term. Nowadays, the bioeconomy is an important socio-economic area, which is reflected in the number of firms dedicated to or using biotechnology. The exploitation of biotechnological patents is an essential task in the management of intellectual capital. This paper explains the multiplicity of factors that influence the exploitation of biotechnological patents; specifically, the internal and external key points of patents exploitation. The external determining factors for patents are: (i) the market need for biotechnological products and services, (ii) the importance of the freedom to operate analysis before entering the market, and (iii) efficiency in prosecution by Patent Offices. This paper primarily focuses on the internal determining factors, more particularly, the characteristics that the patent's owner must take into consideration in order to have a strong, broad subject-matter in the granted patent. The experimentation needed to obtain an adequate scope of the subject- matter in the claims is a critical issue in the exploitation of a patent or patent application.

  13. A development framework for artificial intelligence based distributed operations support systems (United States)

    Adler, Richard M.; Cottman, Bruce H.


    Advanced automation is required to reduce costly human operations support requirements for complex space-based and ground control systems. Existing knowledge based technologies have been used successfully to automate individual operations tasks. Considerably less progress has been made in integrating and coordinating multiple operations applications for unified intelligent support systems. To fill this gap, SOCIAL, a tool set for developing Distributed Artificial Intelligence (DAI) systems is being constructed. SOCIAL consists of three primary language based components defining: models of interprocess communication across heterogeneous platforms; models for interprocess coordination, concurrency control, and fault management; and for accessing heterogeneous information resources. DAI applications subsystems, either new or existing, will access these distributed services non-intrusively, via high-level message-based protocols. SOCIAL will reduce the complexity of distributed communications, control, and integration, enabling developers to concentrate on the design and functionality of the target DAI system itself.

  14. Report on task 4.1.3. - Survey of anticipated functional requirement for operator support systems

    International Nuclear Information System (INIS)

    Silvani, V.


    This is a preliminary report summarizing some topics related to the surveillance activity on anticipated functional requirements of the Operator Support Systems (OSS's) in NPP's. Additional information are expected will be available by analyzing the questionnaire. Functionalities examined are those referring to system functions, user's needs, technology trend, standard status. For practical purposes this document is divided in two main sections: the first section presents a summary of major OSS requirements and related problems as derived from the existing literature; the second section presents a study of OSS to be used to support the operator training presently under development in ENEA. Finally, appendix 2 reports a summary of major functions performed by the OSS's presently in operation or under development in laboratories. Refs, 1 tab

  15. Deployed Analyst History Report, Volume 2. Analytic Support to Combat Operations in the Philippines (2011-2014) (United States)


    Center for Army Analysis Deployed Analyst History Report Volume II Analytic Support to Combat Operations in the Philippines (2011-2014) DECEMBER...Joint Special Operations Task Force – Philippines for Operation ENDURING FREEDOM – Philippines . In early 2011, 1st Special Forces Group (Airborne...reached out to the Center for Army Analysis for assistance in assessing operations conducted in support of Operation ENDURING FREEDOM – Philippines

  16. Analysis of Classroom Debating Strategies in the Field of Biotechnology. (United States)

    Simonneaux, Laurence


    Presents a method for analyzing the didactic strategies put forward to develop students' argumentation skills in biotechnology. Considers five supporting examples and focuses successively on the social characteristics at play and the procedures. Attempts to produce analytical tools to support designers and users of teaching materials in making…

  17. Towards artificial intelligence based diesel engine performance control under varying operating conditions using support vector regression

    Directory of Open Access Journals (Sweden)

    Naradasu Kumar Ravi


    Full Text Available Diesel engine designers are constantly on the look-out for performance enhancement through efficient control of operating parameters. In this paper, the concept of an intelligent engine control system is proposed that seeks to ensure optimized performance under varying operating conditions. The concept is based on arriving at the optimum engine operating parameters to ensure the desired output in terms of efficiency. In addition, a Support Vector Machines based prediction model has been developed to predict the engine performance under varying operating conditions. Experiments were carried out at varying loads, compression ratios and amounts of exhaust gas recirculation using a variable compression ratio diesel engine for data acquisition. It was observed that the SVM model was able to predict the engine performance accurately.

  18. Structural and functional design of WWTP operation decision support system with a case study. (United States)

    Xu, J; Shi, H C; Ke, X Y


    This paper developes the WWTP operation decision support system (ODSS) to simulate the dynamic behavior of the WWTP treatment process based on ASMs (activated sludge models) and WWTP experiential knowledge. The novel structure and functions of ODSS can offer more flexible and general instructions to the WWTP operations. The three independent sub-systems, namely expert system, simulation system and training system, can cooperate to achieve many more functions such as operation alert, fault diagnosis, process simulation and so forth. The expert system based on the dynamic simulation, an essential part of WWTP ODSS, has been proved to be feasible and effective by the implementation at Fang Zhuang WWTP. Our results indicated that the WWTP ODSS has significant potential for improving plant performance and reducing treatment costs by assisting the operators at the decision-making level.

  19. Development and implementation of computerized operator support systems in nuclear installations

    International Nuclear Information System (INIS)


    This report has been prepared to address the development and implementation of computerized operator support systems (COSS) in nuclear installations. The requirements of operators in information management and job performance in a control room environment are discussed. These requirements, which must be agreed to by the operators, provide a focus for the developers of COSS for implementation in an operational environment. The design methodology presents good practice approaches derived from the experience gained and the lessons learned during actual development of the COSS. The team concept, pilot study and structured step by step phases of software development and implementation should help COSS developers to achieve the level of quality and reliability required. 8 figs, 1 tab

  20. Supporting Real-Time Operations and Execution through Timeline and Scheduling Aids (United States)

    Marquez, Jessica J.; Pyrzak, Guy; Hashemi, Sam; Ahmed, Samia; McMillin, Kevin Edward; Medwid, Joseph Daniel; Chen, Diana; Hurtle, Esten


    Since 2003, the NASA Ames Research Center has been actively involved in researching and advancing the state-of-the-art of planning and scheduling tools for NASA mission operations. Our planning toolkit SPIFe (Scheduling and Planning Interface for Exploration) has supported a variety of missions and field tests, scheduling activities for Mars rovers as well as crew on-board International Space Station and NASA earth analogs. The scheduled plan is the integration of all the activities for the day/s. In turn, the agents (rovers, landers, spaceships, crew) execute from this schedule while the mission support team members (e.g., flight controllers) follow the schedule during execution. Over the last couple of years, our team has begun to research and validate methods that will better support users during realtime operations and execution of scheduled activities. Our team utilizes human-computer interaction principles to research user needs, identify workflow processes, prototype software aids, and user test these. This paper discusses three specific prototypes developed and user tested to support real-time operations: Score Mobile, Playbook, and Mobile Assistant for Task Execution (MATE).

  1. The experiences from implementing decision support technology to address water management plans in an operational environment

    Energy Technology Data Exchange (ETDEWEB)

    McArdle, S. [4DM Inc., Toronto, ON (Canada); Tonkin, C. [Ontario Power Generation Inc., Toronto, ON (Canada)


    This presentation described Ontario Power Generation's experience in implementing a decision support tool to enable water management plans for its operations through technology solutions. All hydroelectric producers in Ontario are required to make water management plans in order to maintain water levels and flows in their operating regions. This regulation was created in response to environmental concerns as well as to changes in the electricity market and growth of residential and cottage property near water bodies. In order to keep informed and to address compliance issues, operators and managers need situation awareness information to balance operational decisions. The online Adaptive Water Management System (AWMS) decision support tool was recently adopted by Ontario Power Generation to provide information needed to address the requirements of Water Management Plans. The AWMS provides users with information on water levels and flows; the ability to implement, modify, and manage daily instructions at the facilities; track conditions in the watershed; and, provide a status of compliance. The tool was developed by 4DM Inc. in collaboration with Ottawa St. Lawrence Plant Group for the Madawaska River Watershed Management, a model partnership between operator, regulator and Public Advisory Committee to develop a water management plan.

  2. Innovative Tools for Water Quality/Quantity Management: New York City's Operations Support Tool (United States)

    Wang, L.; Schaake, J. C.; Day, G. N.; Porter, J.; Sheer, D. P.; Pyke, G.


    The New York City Department of Environmental Protection (DEP) manages New York City's water supply, which is comprised of over 20 reservoirs and supplies more than 1 billion gallons of water per day to over 9 million customers. Recently, DEP has initiated design of an Operations Support Tool (OST), a state-of-the-art decision support system to provide computational and predictive support for water supply operations and planning. This presentation describes the technical structure of OST, including the underlying water supply and water quality models, data sources and database management, reservoir inflow forecasts, and the functionalities required to meet the needs of a diverse group of end users. OST is a major upgrade of DEP's current water supply - water quality model, developed to evaluate alternatives for controlling turbidity in NYC's Catskill reservoirs. While the current model relies on historical hydrologic and meteorological data, OST can be driven by forecasted future conditions. It will receive a variety of near-real-time data from a number of sources. OST will support two major types of simulations: long-term, for evaluating policy or infrastructure changes over an extended period of time; and short-term "position analysis" (PA) simulations, consisting of multiple short simulations, all starting from the same initial conditions. Typically, the starting conditions for a PA run will represent those for the current day and traces of forecasted hydrology will drive the model for the duration of the simulation period. The result of these simulations will be a distribution of future system states based on system operating rules and the range of input ensemble streamflow predictions. DEP managers will analyze the output distributions and make operation decisions using risk-based metrics such as probability of refill. Currently, in the developmental stages of OST, forecasts are based on antecedent hydrologic conditions and are statistical in nature. The

  3. Concept of Operations for Integrated Intelligent Flight Deck Displays and Decision Support Technologies (United States)

    Bailey, Randall E.; Prinzel, Lawrence J.; Kramer, Lynda J.; Young, Steve D.


    The document describes a Concept of Operations for Flight Deck Display and Decision Support technologies which may help enable emerging Next Generation Air Transportation System capabilities while also maintaining, or improving upon, flight safety. This concept of operations is used as the driving function within a spiral program of research, development, test, and evaluation for the Integrated Intelligent Flight Deck (IIFD) project. As such, the concept will be updated at each cycle within the spiral to reflect the latest research results and emerging developments

  4. The Externally Supported Ross Operation: Early Outcomes and Intermediate Follow-Up. (United States)

    Jacobsen, Roni M; Earing, Michael G; Hill, Garick D; Barnes, Michael; Mitchell, Michael E; Woods, Ronald K; Tweddell, James S


    The externally supported Ross (supported Ross), consisting of a Dacron (DuPont, Wilmington, DE) graft to support the neoaortic root, has been used in adolescent and adult patients to prevent neoaortic dilatation. Outcomes after the supported Ross technique were compared with the Ross procedure using the standard aortic root replacement technique (standard Ross). This was a retrospective analysis of 36 adolescent and young adult patients who underwent the Ross procedure between 1992 and 2013. The outcomes of supported Ross procedures in 26 patients were compared with the Ross procedure in 10 patients. End points included survival, neoaortic root dilatation, development of neoaortic regurgitation, and the need for reintervention. The median age at operation was 14 years (range, 11 to 31 years), and indications for the operation were mixed lesions (47%), followed by aortic regurgitation (42%) and stenosis (11%). There were no early deaths. The mean follow-up was 2.2 years (range, 1 to 11 years). At the 1-year (p = 0.01) and 3-year (p Ross cohort had a smaller neoaortic root z-score. Neither cohort had a large number of patients with significant neoaortic regurgitation, with 1 patient in the supported cohort compared with 3 patients in the standard cohort. Overall, 4 patients (40%) in the standard Ross cohort had required reintervention, including 3 directed at the neoaortic root. One patient in the supported Ross cohort required early reintervention for revision of the right coronary artery. At intermediate follow-up, patients who underwent the supported Ross technique were less likely to have neoaortic root dilatation compared with patients who underwent a standard Ross procedure. Further studies are needed to evaluate the long-term durability of this technique, particularly in regards to the development of significant aortic regurgitation, the rate of reintervention, and application to younger and smaller patients. Copyright © 2015 The Society of Thoracic Surgeons

  5. Agent-based paradigm for integration of interactive cable television operations and business support systems (United States)

    Wattawa, Scott


    Offering interactive services and data in a hybrid fiber/coax cable system requires the coordination of a host of operations and business support systems. New service offerings and network growth and evolution create never-ending changes in the network infrastructure. Agent-based enterprise models provide a flexible mechanism for systems integration of service and support systems. Agent models also provide a mechanism to decouple interactive services from network architecture. By using the Java programming language, agents may be made safe, portable, and intelligent. This paper investigates the application of the Object Management Group's Common Object Request Brokering Architecture to the integration of a multiple services metropolitan area network.

  6. Project CHECO Southeast Asia Report. Psychological Operations: Air Support in SEA, June 1968-May 1971 (United States)


    from Flight A, 9th SOS at Da Nang flew a Chieu Hoi3 leaflet dropping mission, this chart illustrates the chain of instructional command and guidance...123 Candlestick Flare missionsI flown by the 606th SOS of the 56th Special Operations Wing at Nakhon Phanom, Thailand. The 606th SOS normally 1968. Both types 3of aircraft supported leaflet drops over the Trail. The C-123s flew psychological leaflet drops as an add-on to their Candlestick

  7. Biotechnological Processes in Microbial Amylase Production

    Directory of Open Access Journals (Sweden)

    Subash C. B. Gopinath


    Full Text Available Amylase is an important and indispensable enzyme that plays a pivotal role in the field of biotechnology. It is produced mainly from microbial sources and is used in many industries. Industrial sectors with top-down and bottom-up approaches are currently focusing on improving microbial amylase production levels by implementing bioengineering technologies. The further support of energy consumption studies, such as those on thermodynamics, pinch technology, and environment-friendly technologies, has hastened the large-scale production of the enzyme. Herein, the importance of microbial (bacteria and fungi amylase is discussed along with its production methods from the laboratory to industrial scales.

  8. Hungarian national report on activities related to operator support systems for nuclear power plants

    International Nuclear Information System (INIS)

    Adorjan, F.; Lux, I.; Vegh, J.; Vegh, E.


    According to the summary report of the Co-ordinated Research Meeting on ''Operator Support Systems in Nuclear Power Plants'', 13-16 October 1992, the national reports shall cover the following topics: General summary of the national activity; description of the results in the framework of the CRP; overview of the OSS related recent national activity. Accordingly, in the first section we give an overview of the operator support systems developed in Hungary. The second section summarizes the data collected in order to comply with the Tasks 4.1.1 and 4.1.2 of the CRP. In the third section we summarize the most recent works pertaining to the development and application of OSS at nuclear power plants

  9. Proposal for the award of a contract for industrial support for logistics and stores operations

    CERN Document Server


    This document concerns the award of a contract for industrial support for logistics and stores operations. Following a market survey carried out among 59 firms in ten Member States, a call for tenders (IT-2401/SPL/Revised) was sent on 11 March 1999 to five firms and four consortia in five Member States. By the closing date, CERN had received eight tenders from five Member States. The Finance Committee is invited to agree to the negotiation of a contract with the consortium ISS GEBÄUDESERVICE (DE) - ISS SERVISYSTEM (CH) the lowest bidder complying with the specification, for industrial support for logistics and stores operations over a period of three years, starting on 1st January 2000, for a total amount of 3 830 000 Swiss francs, not subject to revision. The contract will include an option for two one-year extensions beyond the initial three-year period.

  10. An information offering system for operation support based on plant functional structure

    International Nuclear Information System (INIS)

    Ohga, Yukiharu; Seki, Hiroshi


    A plant information offering system was proposed to support operators in their selection and confirmation of the required information for plant operation under transient conditions in nuclear power plants. The system features include an automatic selection method for information and a dialog input method. The former selects plant information in response to plant status changes and operators' demands. The selection is performed based on the knowledge and data as structured by the plant functional structure; i.e. a means-ends abstraction hierarchy model. In the latter, both speech and CRT touch inputs are transformed into words in Japanese to realize an arbitrary input mode combination. The words are analyzed as a sentence before transforming them into a demand for related programs. A prototype system was evaluated using a BWR simulator, assuming abnormal transients such as loss of feedwater. The contents of the offered information were checked based on emergency operation guidelines. It was confirmed that appropriate information items are automatically selected in real time. Answers are generated in reply to the operators' demands. They include information added to reflect the plant conditions. As for dialog, simple and quick input is realized by combining speech and CRT touch according to the operating situation. (author)

  11. Extended Operation Testing of Stirling Convertors in Support of Stirling Radioisotope Power System Development (United States)

    Lewandowski, Edward J.; Schreiber, Jeffrey G.; Wilson, Scott D.; Oriti, Salvatore M.; Cornell, Peggy; Schifer, Nicholas


    100 We class Stirling convertors began extended operation testing at NASA Glenn Research Center (GRC) in 2003 with a pair of Technology Demonstration Convertors (TDCs) operating in air. Currently, the number of convertors on extended operation test has grown to 12, including both TDCs and Advanced Stirling Convertors (ASCs) operating both in air and in thermal vacuum. Additional convertors and an electrically heated radioisotope generator will be put on test in the near future. This testing has provided data to support life and reliability estimates and the quality improvements and design changes that have been made to the convertor. The convertors operated 24/7 at the nominal amplitude and power levels. Performance data were recorded on an hourly basis. Techniques to monitor the convertors for change in internal operation included gas analysis, vibration measurements, and acoustic emission measurements. This data provided a baseline for future comparison. This paper summarizes the results of over 145,000 hr of TDC testing and 40,000 hr of ASC testing and discusses trends in the data. Data shows the importance of improved materials, hermetic sealing, and quality processes in maintaining convertor performance over long life.

  12. Strategic management of biotechnology agents. (United States)

    Huber, S L


    The use of biologic response modifiers to demonstrate a value-driven approach to strategic management by pharmacists is described. To participate in decisions on the use of technology in their institutions, pharmacists must practice strategic management. This process includes environmental scanning, analysis of clinical and pharmacoeconomic data, and development of clinical management approaches. It is ideal for analyzing biologic response modifiers such as filgrastim and sargramostim. Emphasis must be placed on maximizing the fit among the products, the institution, and the health care environment. Pharmacists will find plentiful opportunities for clinical management with biotechnology agents. Practitioners who specialize in determining the total cost of care by using pharmacoeconomic methods are needed, as are practitioners trained to monitor the complicated biotechnology agents. Also, the institution needs to forecast accurately the impact of emerging biotechnology agents. If pharmacists can develop and control clinical, pharmacoeconomic, and reimbursement information databases for biotechnology agents, the pharmacy profession will be in a strong position to meet the challenges of biotechnology and realize the inherent opportunities.

  13. Spectral Theory for Schrodinger Operators with delta-Interactions Supported on Curves in R-3

    Czech Academy of Sciences Publication Activity Database

    Behrndt, J.; Frank, R. L.; Kuhn, C.; Lotoreichik, Vladimir; Rohleder, J.


    Roč. 18, č. 4 (2017), s. 1305-1347 ISSN 1424-0637 R&D Projects: GA ČR(CZ) GA14-06818S Institutional support: RVO:61389005 Keywords : spectral theory * scattering theory * self-adjoint Schrodinger operators Subject RIV: BE - Theoretical Physics OBOR OECD: Atomic, molecular and chemical physics (physics of atoms and molecules including collision, interaction with radiation, magnetic resonances, Mössbauer effect) Impact factor: 1.599, year: 2016

  14. Man-mashine communication improvements in computerized operator support system by new technologies

    International Nuclear Information System (INIS)

    Tai, I.; Seki, E.; Fukumoto, A.; Mori, N.; Tsuchida, M.; Itoh, J.; Tanaka, K.


    Improvement of the man-machine interface performance is under way as Computerized Operator Support System for nuclear power plants in Japan. This paper describes several improved points in the design of man-mashine interface, especially on the console, based on the evaluation of the conventional design and by taking into account the performance test results of new man-machine interfacing tools. (author)

  15. The use of operating experience data for supporting the completeness of system models

    International Nuclear Information System (INIS)

    Kalfsbeek, H.W.


    This paper describes the use of the Abnormal Occurrences Reporting System (AORS) of the Commission of the European Communities for PRA/PSA's of nuclear power plants, in particular during the modelisation phase of such study. The AORS contains homogenised information on safety related events from various countries, covering about 780 reactor years of operation. A semi-automatic procedure is presented for retrieving the observed paths leading (potentially) to a pre-specified top event, e.g. the failure of an emergency system. This procedure is based on the feature that renders the AORS a unique system among the international safety related event databases, namely the storage of causal sequences extracted from each event report. It supports the PSA analyst in improving the degree of completeness of the system-, subsystem- and component models, system interactions and operator behaviour models by exploiting efficiently the large amount of operating experience available to date. (orig./HSCH)

  16. Deployable Network Operations Center (DNOC): A Collaborative Technology Infostructure Designed to Support Tactical Sensor-Decision Maker Network Operations

    National Research Council Canada - National Science Library

    Johnson, Shawn E


    .... The increasing use of expeditionary and special operations forces operating in ad hoc, dynamic, and tactical environments poses a need for an adaptable, flexible, and responsive Deployable Network Operations Center (DNOC...

  17. The Application of Operational Art to Health Service Support: A Case Study of the Korean and Vietnam Wars (United States)


    The Application of Operational Art to Health Service Support: A Case Study of the Korean and Vietnam Wars A Monograph by MAJ Brian M. Downs...of Operational Art to Health Service Support: A Case Study of the Korean and Vietnam Wars 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM...HSS operations during the opening six months of the Korean War , contrasted with the stable HSS operations in the Vietnam War , would provide insight

  18. Intelligence, Surveillance, and Reconnaissance Support to Humanitarian Relief Operations within the United States: Where Everyone is in Charge

    National Research Council Canada - National Science Library

    Sovada, Jennifer P


    ... the leadership of the military, federal government, and state governments since Hurricane Katrina. These organizations have deemed ISR support essential to conducting timely, effective, and responsive relief operations...

  19. Development of a dynamic operation permission system to support operations in an anomalous situation of PWR plants

    International Nuclear Information System (INIS)

    Gofuku, Akio; Nishio, Takuya; Ohi, Tadashi; Ito, Koji


    This paper describes a proto-type dynamic operation permission system to avoid commission errors of operators. The system lies between CRT-based operation panels and plant control systems and checks an operation by operators if it follows typical operation procedure described in operation manuals and it has suitable effects on plant condition. The applicability of the proto-type system is demonstrated through the application to the recovery operations of a steam generator tube rupture accident of a three-loop pressurized water reactor plant

  20. The impact of industrial biotechnology. (United States)

    Soetaert, Wim; Vandamme, Erick


    In this review, the impact of industrial (or "white") biotechnology can have on our society and economy is discussed. An overview is given of industrial biotechnology and its applications in a number of product categories ranging from food ingredients, vitamins, bio-colorants, solvents, plastics and biofuels. The use of fossil resources is compared with renewable resources as the preferred feedstock for industrial biotechnology. A brief discussion is also given of the expected changes in society and technology, ranging from the shift in the supply of resources, the growing need for efficiency and sustainability of the production systems, changing consumer perception and behaviour and changing agricultural systems and practices. Many of these changes are expected to speed up the transition from a fossil-based to a bio-based economy and society.

  1. Developing a Logistics Data Process for Support Equipment for NASA Ground Operations (United States)

    Chakrabarti, Suman


    The United States NASA Space Shuttle has long been considered an extremely capable yet relatively expensive rocket. A great part of the roughly US $500 million per launch expense was the support footprint: refurbishment and maintenance of the space shuttle system, together with the long list of resources required to support it, including personnel, tools, facilities, transport and support equipment. NASA determined to make its next rocket system with a smaller logistics footprint, and thereby more cost-effective and quicker turnaround. The logical solution was to adopt a standard Logistics Support Analysis (LSA) process based on GEIA-STD-0007 which is the successor of MIL-STD-1388-2B widely used by U.S., NATO, and other world military services and industries. This approach is unprecedented at NASA: it is the first time a major program of programs, Project Constellation, is factoring logistics and supportability into design at many levels. This paper will focus on one of those levels NASA ground support equipment for the next generation of NASA rockets and on building a Logistics Support Analysis Record (LSAR) for developing and documenting a support solution and inventory of resources for. This LSAR is actually a standards-based database, containing analyses of the time and tools, personnel, facilities and support equipment required to assemble and integrate the stages and umbilicals of a rocket. This paper will cover building this database from scratch: including creating and importing a hierarchical bill of materials (BOM) from legacy data; identifying line-replaceable units (LRUs) of a given piece of equipment; analyzing reliability and maintainability of said LRUs; and therefore making an assessment back to design whether the support solution for a piece of equipment is too much work, i.e., too resource-intensive. If one must replace or inspect an LRU too much, perhaps a modification of

  2. Is biotechnology the new alchemy? (United States)

    Kirkham, Georgiana


    In this article I examine similarities between the science and ethics of biotechnology on the one hand, and those of alchemy on the other, and show that the understanding of nature and naturalness upon which many contemporary ethical responses to biotechnology are predicated is, in fact, significantly similar to the understanding of nature that was the foundation of the practice of alchemy. In doing so I demonstrate that the ethical issues and social responses that are currently arising from advances in the field of biotechnology are interestingly similar to those that arose in reaction to the practice and prevalence of alchemy from its inception in Europe in the mid-twelfth century until at least the early modern period. I argue that a proper conception of the ethical issues and a sensible interpretation of the power and the promise of the science of biotechnology are most likely if we understand such attitudes to nature, and to the ethical issues surrounding technological and scientific developments, in terms of an historical and cultural continuum. That is, we should regard biotechnology as merely the latest in a string of technological and scientific developments rather than, as is often alleged, as something entirely new, requiring its own special ethical response. Finally, I suggest that examining the parallels between the ethical issues generated by alchemy and by biotechnology show us that such issues are best situated and discussed within a framework of virtue ethics, as it allows us to think seriously about the relationship between art and nature and the proper role of humans in relation to their technology.

  3. Sitaxsentan (ICOS-Texas Biotechnology). (United States)

    Wu-Wong, J R


    ICOS-Texas Biotechnology is developing the endothelin A (ETA) receptor antagonist, sitaxsentan, for the potential treatment of pulmonary hypertension, congestive heart failure (CHF), chronic obstructive pulmonary disease and subarachnoid hemorrhage [205713], [302200]. The compound is in phase IIa trials as an iv formulation for CHF and has completed phase I safety trials as an oral formulation [272071]. Phase II/III trials for pulmonary hypertension are planned for the first quarter of 2001 [3945711]. In June 2000, ICOS and Texas Biotechnology established a joint venture to develop and commercialize endothelin antagonists [370007]. US-05591761 was issued to Texas in January 1997, covering TBC-11251 and several related isomers [2309301.

  4. Environmental Biotechnology Research Lab (United States)

    Federal Laboratory Consortium — This laboratory supports aspects of the life cycle mission for ARDEC by investigating the performance of new treatment technologies to destroy waste streams from the...

  5. States of uncertainty: governing the empire of biotechnology. (United States)

    Forbes, Ian


    The biotechnological revolution presents states and governments with a set of challenges that they have difficulty meeting. Part of the problem is associated with common perceptions of the speed, volume and the radical uncertainty of the new developments. Globalisation is also implicated, especially in relation to the development of the knowledge economy and the role of multinational actors. This in turn contributes to the apparent decline in the confidence of the public that national governments will be effective in addressing mounting concern about the dangers inherent in new techniques and products. Under these circumstances, 'normal' governance begins to look more like 'failure' governance. This article asks whether the effects of the biotechnological revolution on governance can adequately be explained by the critique of imperialism proposed by Michael Hardt and Antonio Negri, and whether the state is in danger of becoming implicated in sponsorship of modernist schemes to improve the human condition of the kind analysed by James E Scott. Biotechnology does appear to have imperial qualities, while there are strong reasons for states to see biotechnology as a feasible and desirable set of developments. For some critics of biotechnology, like Francis Fukuyama, this is a lethal combination, and the powers of the state should be used to stop biotechnological development. Others, by contrast and more pragmatically, propose a check on what the state will support by the application of precautionary principles. The article concludes that the association between the biotechnology empire and the state, combined with the inescapable duty of the state to be the risk manager of last resort, alerts us to the complexities of uncertainty at the same time as it renders a merely restrictive precautionary approach impracticable.

  6. Usefulness of a device for body support during operations performed while standing. (United States)

    Ito, Kiyoshi; Horiuchi, Tetsuyoshi; Seguchi, Tatsuya; Hongo, Kazuhiro


    During microsurgical procedures, manipulations are often performed using a foot switch while the surgeon stands on one foot. This position can easily result in body axis instability and greater musculoskeletal loading. To support the surgeon's posture, we have developed a tool called the "Surgeon's Body Support Device." The objective of this study was to determine the efficacy of this device by analyzing surgeons' kinematics and musculoskeletal loading during simulated operations undertaken while standing. Fourteen surgeons volunteered to perform simulations of surgery while standing. To analyze motion kinetics and musculoskeletal loading with and without this device, a three-axis accelerometer and surface electromyography (SEMG) sensors were attached to the subjects. Compared with not using the supportive device, the axis of the surgeon's body was significantly more stable when the support device was used (P = .001). The evenness of motion also tended to be superior when the device was utilized (P = .009). Simulations performed using the device significantly reduced the musculoskeletal loading on the ventral side of the left foot by 70 % compared with simulations performed not using the device (P = .001). Data from SEMG sensor placed on the right hand, which performs the surgical manipulations, indicated that simulations performed using the device generated approximately 10 % of the musculoskeletal load generated when the device was not used (P = .001). The Surgeon's Body Support Device appears to improve maneuverability and reduce musculoskeletal loading during simulated surgical procedures undertaken while standing.

  7. Biotechnology developments in Uganda and associated challenges ...

    African Journals Online (AJOL)

    ... biotechnology programmes and strengthening interactions among the actors both locally and internationally; integrating biotechnology into institutional programmes and regulatory instruments; putting in place technology management policies and developing capacities for their implementation; encouraging private sector ...

  8. Applied thermodynamics: A new frontier for biotechnology

    DEFF Research Database (Denmark)

    Mollerup, Jørgen


    The scientific career of one of the most outstanding scientists in molecular thermodynamics, Professor John M. Prausnitz at Berkeley, reflects the change in the agenda of molecular thermodynamics, from hydrocarbon chemistry to biotechnology. To make thermodynamics a frontier for biotechnology...

  9. Modernizing the Regulatory System for Biotechnology Products (United States)

    This Web page describes the continuing effort to modernize the federal regulatory system for biotechnology products as well as clarify various roles of EPA, FDA and USDA in evaluating new biotechnology products.

  10. Biotechnology and industrial ecology: new challenges for a ...

    African Journals Online (AJOL)

    One of the strategies proposed to mitigate climate change is to lower dependency on fossil fuels by substituting renewable biomass. This strategy has several co-benefits for human health and the environment because it supports investments in agricultural biotechnology while reducing the adverse health impacts of ...

  11. Great expectations: The state of biotechnology research and ...

    African Journals Online (AJOL)

    As biotechnology industries are knowledge-intensive, Research and Experimental Development (R and D) are key drivers of growth. Governments and businesses have an interest in creating an environment that stimulates R and D and the commercialisation thereof. Discourse relating to the best means to support ...

  12. Estimation of the laser cutting operating cost by support vector regression methodology (United States)

    Jović, Srđan; Radović, Aleksandar; Šarkoćević, Živče; Petković, Dalibor; Alizamir, Meysam


    Laser cutting is a popular manufacturing process utilized to cut various types of materials economically. The operating cost is affected by laser power, cutting speed, assist gas pressure, nozzle diameter and focus point position as well as the workpiece material. In this article, the process factors investigated were: laser power, cutting speed, air pressure and focal point position. The aim of this work is to relate the operating cost to the process parameters mentioned above. CO2 laser cutting of stainless steel of medical grade AISI316L has been investigated. The main goal was to analyze the operating cost through the laser power, cutting speed, air pressure, focal point position and material thickness. Since the laser operating cost is a complex, non-linear task, soft computing optimization algorithms can be used. Intelligent soft computing scheme support vector regression (SVR) was implemented. The performance of the proposed estimator was confirmed with the simulation results. The SVR results are then compared with artificial neural network and genetic programing. According to the results, a greater improvement in estimation accuracy can be achieved through the SVR compared to other soft computing methodologies. The new optimization methods benefit from the soft computing capabilities of global optimization and multiobjective optimization rather than choosing a starting point by trial and error and combining multiple criteria into a single criterion.

  13. Transportation-Driven Mars Surface Operations Supporting an Evolvable Mars Campaign (United States)

    Toups, Larry; Brown, Kendall; Hoffman, Stephen J.


    This paper describes the results of a study evaluating options for supporting a series of human missions to a single Mars surface destination. In this scenario the infrastructure emplaced during previous visits to this site is leveraged in following missions. The goal of this single site approach to Mars surface infrastructure is to enable "Steady State" operations by at least 4 crew for up to 500 sols at this site. These characteristics, along with the transportation system used to deliver crew and equipment to and from Mars, are collectively known as the Evolvable Mars Campaign (EMC). Information in this paper is presented in the sequence in which it was accomplished. First, a logical buildup sequence of surface infrastructure was developed to achieve the desired "Steady State" operations on the Mars surface. This was based on a concept of operations that met objectives of the EMC. Second, infrastructure capabilities were identified to carry out this concept of operations. Third, systems (in the form of conceptual elements) were identified to provide these capabilities. This included top-level mass, power and volume estimates for these elements. Fourth, the results were then used in analyses to evaluate three options (18t, 27t, and 40t landed mass) of Mars Lander delivery capability to the surface. Finally, Mars arrival mass estimates were generated based upon the entry, descent, and landing requirements for inclusion in separate assessments of in-space transportation capabilities for the EMC.


    Directory of Open Access Journals (Sweden)

    L. P. Buchatsky


    Full Text Available The latest progress in biotechnology on fish aquaculture and different modern methods of investigations for increasing of fish productivity in aquaculture are analyzed. Except for the applied aspect, the use of modern biotechnological methods of investigations opens new possibilities for fundamental researches of sex-determining mechanisms, polyploidy, distant hybridization, and developmental biology of bony fishes. Review contains examples of utilizing modern biotechnology methods to obtain transgenic fishes with accelerated growth and for designing surrogate fishes. Methods for receiving unisexual shoals of salmon and sturgeon female fishes with the view of obtaining a large quantity of caviar, as well as receiving sterile (triploid fishes are analyzed. Great attention is given to androgenesis, particularly to disperm one, in connection with the problem of conserving rare and vanishing fish species using only sperm genetic material. Examples how distant hybrids may be obtained with the use of disperm androgenesis and alkylated DNA are given. Methods of obtaining fish primordium germ cells, recent developments in cultivation of fish stem cells and their use in biotechnology, as well as ones of transplantation of oogonium and spermatogonium to obtain surrogate fishes. The examples of successful experiments on spermatogonial xenotransplantation and characteristic of antifreezing fish proteins and also the prospect of their practical usage are given.

  15. The Development of Plant Biotechnology. (United States)

    Torrey, John G.


    Examines major lines of thought leading to what is meant by plant biotechnology, namely, the application of existing techniques of plant organ, tissue, and cell culture, plant molecular biology, and genetic engineering to the improvement of plants and of plant productivity for the benefit of man. (JN)

  16. The Future of Plant Biotechnology (United States)

    Plant biotechnology has been wildly successful and has literally transformed plant agriculture. There are still undulating concerns about safety and sustainability that critics demand to be addressed. In that light, there are some biotechnoloogies that are being developed that might not only improve...

  17. Acinetobacter: environmental and biotechnological applications ...

    African Journals Online (AJOL)

    Among microbial communities involved in different ecosystems such as soil, freshwater, wastewater and solid wastes, several strains belonging to the genus of Acinetobacter have been attracting growing interest from medical, environmental and a biotechnological point of view. Bacteria of this genus are known to be ...

  18. Biological Constraints in Algal Biotechnology

    Czech Academy of Sciences Publication Activity Database

    Torzillo, G.; Pushparaj, B.; Masojídek, Jiří; Vonshak, A.


    Roč. 8, - (2003), s. 338-348 ISSN 0006-3592 R&D Projects: GA MŠk LN00A141 Institutional research plan: CEZ:MSM 123100001 Keywords : outdoor cultures * photobioreactors * oxygen stress Subject RIV: EI - Biotechnology ; Bionics Impact factor: 2.173, year: 2003

  19. Re-Framing Biotechnology Regulation. (United States)

    Peck, Alison

    Biotechnology is about to spill the banks of federal regulation. New genetic engineering techniques like CRISPR-Cas9 promise revolutionary breakthroughs in medicine, agriculture, and public health—but those techniques would not be regulated under the terms of the Coordinated Framework for Regulation of Biotechnology. This revolutionary moment in biotechnology offers an opportunity to correct the flaws in the framework, which was hastily patched together at the advent of the technology. The framework has never captured all relevant technologies, has never satisfied the public that risk is being effectively managed, and has never been accessible to small companies and publicly-funded labs that increasingly are positioned to make radical, life-saving innovations. This Article offers a proposal for new legislation that would reshape biotechnology regulation to better meet these goals. Key reforms include tying regulation to risk rather than technology category; consolidating agency review; capturing distinct regulatory expertise through inter-agency consultations; creating a clearinghouse to help guide applicants and disseminate information; setting up more comprehensive monitoring of environmental effects; and providing federal leadership to fill key data gaps and address socio-economic impacts.

  20. Ethical perception of modern biotechnology

    African Journals Online (AJOL)



    Sep 30, 2011 ... ensure food security and to boost the country's economy. (Latifah et al., 2007). Successful development and commercialisation of modern biotechnology products in. *Corresponding author. E-mail:, Tel: + 603-. 89216907. Fax: +603-89252976. Abbreviations: GMOs, Genetically modified ...

  1. Seminar on Nano-biotechnology

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 13; Issue 12. Seminar on Nano-biotechnology. Information and Announcements Volume 13 Issue 12 December 2008 pp 1191-1191. Fulltext. Click here to view fulltext PDF. Permanent link: ...

  2. Biotechnological sulphide removal with oxygen

    NARCIS (Netherlands)

    Buisman, C.


    This thesis deals with the development of a new process for biotechnological sulphide removal from wastewater, in which it is attempted to convert sulphide into elemental sulphur by colourless sulphur bacteria. The toxicity, corrosive properties, unpleasant odor and high oxygen demand of sulphide

  3. Retinal blood vessel segmentation using line operators and support vector classification. (United States)

    Ricci, Elisa; Perfetti, Renzo


    In the framework of computer-aided diagnosis of eye diseases, retinal vessel segmentation based on line operators is proposed. A line detector, previously used in mammography, is applied to the green channel of the retinal image. It is based on the evaluation of the average grey level along lines of fixed length passing through the target pixel at different orientations. Two segmentation methods are considered. The first uses the basic line detector whose response is thresholded to obtain unsupervised pixel classification. As a further development, we employ two orthogonal line detectors along with the grey level of the target pixel to construct a feature vector for supervised classification using a support vector machine. The effectiveness of both methods is demonstrated through receiver operating characteristic analysis on two publicly available databases of color fundus images.

  4. Operational knowledge management: identification of knowledge objects, operation methods, and goals and means for the support function

    NARCIS (Netherlands)

    Wijnhoven, Alphonsus B.J.M.


    Though much has been written about knowledge management, this field has not been described extensively from an operational management perspective. Consequently, knowledge management seems difficult to implement at the operational levels of the organisations. To solve this problem, the abstract

  5. [Importance of reproductive biotechnology in cattle in Europe]. (United States)

    Wrenzycki, C; Stinshoff, H


    Reproductive biotechnology has manifold applications and includes a great innovation potential in livestock. Due to the global changes the new findings and techniques can aid to meet the future challenges. The use of biotechnology in animal production can guarantee enough high quality food for the whole population. Genetic resources of animals can be preserved via sperm and embryo banking. Early diagnosis of hereditary defects, generation of offspring with predetermined sex and the avoidance of animal transports for breeding employing shipment of frozen embryos will improve animal welfare. A special application is the use of animal models for human assisted reproductive technologies. Therefore, not only in Germany research related to the methodologies in reproductive biotechnology and their improvement need to be supported.

  6. Surgical support for low-intensity conflict, limited warfare, and special operations. (United States)

    Rush, Robert M


    Low-intensity conflicts and special operations present a wide range of injury scenarios for military and civilian surgeons alike. Harsh environments, difficult and high-risk missions, long lines of communication, and isolated locations are but some of the factors that create challenge in providing care for patients in this category. Often surgeons and other medical personnel are faced with many additional medical and nonmedical tasks outside their usual expertise because of the small number of support personnel and medical footprints brought forward in these missions.

  7. Operating and Support Costs and Affordability of a 324 Ship Naval Battle Force (United States)


    Procurement (otherwise known as Investment) • Operating and Support (O&S) • Disposal As seen in a typical life cycle cost structure for a ship...deliveries of one ship, extensions of others, or simply the rearrangement of classification of ships within the battle force can all greatly impact...b2 b3 b4 b5 CVN-68 9.39277E-27 0.999031097 18841399.38 0.9997 1.01 Man Pwr 3.03901E-11 0.935288857 -10,572,406,323.83 5293066.75 52603.22 Fuel

  8. Method of Choosing the Information Technology System Supporting Management of the Military Aircraft Operation

    Directory of Open Access Journals (Sweden)

    Barszcz Piotr


    Full Text Available The paper presents a method of choosing the information technology system, the task of which is to support the management process of the military aircraft operation. The proposed method is based on surveys conducted among direct users of IT systems used in aviation of the Polish Armed Forces. The analysis of results of the surveys was conducted using statistical methods. The paper was completed with practical conclusions related to further usefulness of the individual information technology systems. In the future, they can be extremely useful in the process of selecting the best solutions and integration of the information technology systems

  9. Computer-aided acquisition and logistics support (CALS): Concept of Operations for Depot Maintenance

    Energy Technology Data Exchange (ETDEWEB)

    Bourgeois, N.C.; Greer, D.K.


    This CALS Concept of Operations for Depot Maintenance provides the foundation strategy and the near term tactical plan for CALS implementation in the depot maintenance environment. The user requirements enumerated and the overarching architecture outlined serve as the primary framework for implementation planning. The seamless integration of depot maintenance business processes and supporting information systems with the emerging global CALS environment will be critical to the efficient realization of depot user's information requirements, and as, such will be a fundamental theme in depot implementations.

  10. Clinical Space Medicine Products as Developed by the Medical Operations Support Team (MOST) (United States)

    Polk, James D.; Doerr, Harold K.; Hurst, Victor W., IV; Schmid, Josef


    Medical Operations Support Team (MOST) is introducing/integrating teaching practices associated with high fidelity human patient simulation into the NASA culture, in particular, into medical training sessions and medical procedure evaluations. Current/Future Products iclude: a) Development of Sub-optimal Airway Protocols for the International Space Station (ISS) using the ILMA; b) Clinical Core Competency Training for NASA Flight Surgeons (FS); c) Post-Soyuz Landing Clinical Training for NASA FS; d) Experimental Integrated Training for Astronaut Crew Medical Officers and NASA FS; and e) Private Clinical Refresher Training.

  11. Office of Naval Research (ONR) Support for R/V Point Sur Ship Operations (United States)


    4th Floor "San Jose, CA 95112 8. PERFORMING ORGANIZATION REPORT NUMBER N/A 9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES...include area code) (831) 771-4402 Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std. 239.18 201 b0 U50^ : bAN Jü U NIV E ’ January 8...Landing Marine Laboratories (MLML] Marine Operations 7539 Sandholdt Road Moss Landing, CA 95039 Document Title: Office of Naval Research (ONR) Support

  12. Building a normative decision support system for clinical and operational risk management in hemodialysis. (United States)

    Cornalba, Chiara; Bellazzi, Roberto G; Bellazzi, Riccardo


    This paper describes the design and implementation of a decision support system for risk management in hemodialysis (HD) departments. The proposed system exploits a domain ontology to formalize the problem as a Bayesian network. It also relies on a software tool, able to automatically collect HD data, to learn the network conditional probabilities. By merging prior knowledge and the available data, the system allows to estimate risk profiles both for patients and HD departments. The risk management process is completed by an influence diagram that enables scenario analysis to choose the optimal decisions that mitigate a patient's risk. The methods and design of the decision support tool are described in detail, and the derived decision model is presented. Examples and case studies are also shown. The tool is one of the few examples of normative system explicitly conceived to manage operational and clinical risks in health care environments.

  13. Biotechnology: Challenge for the food industry

    Directory of Open Access Journals (Sweden)

    Popov Stevan


    Full Text Available According to the broadest definition, biotechnology is the use of living matter (plants, animals and microorganisms in industry, environment protection, medicine and agriculture. Biotechnology takes a key position in the field of food processing during thousands of years. Last about fifty years brought dynamical development of knowledges in the natural sciences especially in domain of genetics and manipulation of genes. Biotechnology for which active role in the on-coming times could be foreseen, not only with respect of R&D, but also in general technological development represents scope of priority in the USA and in European Union (EU as well. It is accepted that the results achieved in biotechnology oversize scientific domain and find their entrance into economics, legislation, quality of life and even of politics. Corresponding with the definition of biotechnology as "the integration of natural sciences and engineering in the application of microorganisms, cells, their components and molecular analogues in production (General assembly of the European federation for Biotechnology, 1989 European Commission (1999 adopted the biotechnological taxonomy, i.e. fields and sub-fields of biotechnology. R&D activities in this domain are oriented to eight fields and branched through them. Fields of biotechnology (EC, 1999 are: 1 Plant biotechnology (agricultural cultivars, trees, bushes etc; 2 Animal biotechnology; 3 Biotechnology in environment protection; 4 Industrial biotechnology (food, feed, paper, textile, pharmaceutical and chemical productions; 5 Industrial biotechnology (production of cells and research of cells - producers of food and of other commodities; 6 Development of humane and veterinarian diagnostics (therapeutical systems 7 Development of the basic biotechnology, and 8 Nontechnical domains of biotechnology. In concordance with some judgments, in the World exist about 4000 biotechnological companies. World market of biotechnological

  14. Operation and maintenance manual for the temporary septic holding tank at the 100-D remedial action support facility. Revision 1

    International Nuclear Information System (INIS)

    Kelty, G.G.


    This manual provides detailed information for the operation and maintenance of the sanitary wastewater holding system at the 100-D Remedial Action Support Facility located in the 100-DR-1 Operable Unit of the Hanford Site. This document describes operations, including the type and frequency of required maintenance, and system failure response procedures

  15. Operation and maintenance manual for the temporary septic holding tank at the 100-D remedial action support facility. Revision 2

    International Nuclear Information System (INIS)

    Kelty, G.G.


    This manual was prepared to provide detailed information for the operation and maintenance of the sanitary wastewater holding system at the 100-D Remedial Action Support Facility located in the 100-DR-1 Operable Unit at the Hanford Site. This document describes operations, including the type and frequency of required maintenance, and system failure response procedures

  16. Doubling and do-support in verbal fronting: Towards a typology of repair operations

    Directory of Open Access Journals (Sweden)

    Johannes Hein


    Full Text Available Most known languages seem to follow the intuitive and economical implication that if they show a repair such as verb doubling or 'do'-support when just the verb is fronted, they also show that same repair when the verb is fronted together with its internal argument(s (provided that the language has both types of fronting. In this paper, I present data from Asante Twi, where the verb is doubled in the former case but there is 'do'-support in the latter instead. I argue that the attested patterns can be accounted for under the Copy Theory of Movement by introducing different orders of the operations Chain Reduction (CR and head movement (HM at PF (analogous to what Schoorlemmer 2012 proposed for Chain Reduction and Local Dislocation. CR either bleeds HM giving rise to consistent 'do'-support (as in German or counterbleeds it leading to consistent verb doubling (as in Hebrew. The Asante Twi pattern is a result of the interaction of the bleeding order with Ā-head movement, where the bleeding effect of the order is neutralised by the inability of Ā-head movement to form chains, which is rooted in the Chain Uniformity Condition (Chomsky 1995. The account provides a unified minimalist analysis of verb doubling and 'do'-support in verbal fronting, which derives all attested patterns but correctly precludes the derivation of the unattested reverse Asante Twi pattern.

  17. Space Biotechnology and Commercial Applications University of Florida (United States)

    Phillips, Winfred; Evanich, Peggy L.


    The Space Biotechnology and Commercial Applications grant was funded by NASA's Kennedy Space Center in FY 2002 to provide dedicated biotechnology and agricultural research focused on the regeneration of space flight environments with direct parallels in Earth-based applications for solving problems in the environment, advances in agricultural science, and other human support issues amenable to targeted biotechnology solutions. This grant had three project areas, each with multiple tasks. They are: 1) Space Agriculture and Biotechnology Research and Education, 2) Integrated Smart Nanosensors for Space Biotechnology Applications, and 3) Commercial Applications. The Space Agriculture and Biotechnology Research and Education (SABRE) Center emphasized the fundamental biology of organisms involved in space flight applications, including those involved in advanced life support environments because of their critical role in the long-term exploration of space. The SABRE Center supports research at the University of Florida and at the Space Life Sciences Laboratory (SLSL) at the Kennedy Space Center. The Integrated Smart Nanosensors for Space Biotechnology Applications component focused on developing and applying sensor technologies to space environments and agricultural systems. The research activities in nanosensors were coordinated with the SABRE portions of this grant and with the research sponsored by the NASA Environmental Systems Commercial Space Technology Center located in the Department of Environmental Engineering Sciences. Initial sensor efforts have focused on air and water quality monitoring essential to humans for living and working permanently in space, an important goal identified in NASA's strategic plan. The closed environment of a spacecraft or planetary base accentuates cause and effect relationships and environmental impacts. The limited available air and water resources emphasize the need for reuse, recycling, and system monitoring. It is essential to

  18. Model based decision support system of operating settings for MMAT nozzles

    Directory of Open Access Journals (Sweden)

    Fritz Bradley Keith


    Full Text Available Droplet size, which is affected by nozzle type, nozzle setups and operation, and spray solution, is one of the most critical factors influencing spray performance, environment pollution, food safety, and must be considered as part of any application scenario. Characterizing spray nozzles can be a timely and expensive proposition if the entire operational space (all combinations of spray pressure and orifice size, what influence flow rate is to be evaluated. This research proposes a structured, experimental design that allows for the development of computational models for droplet size based on any combination of a nozzle’s potential operational settings. The developed droplet size determination model can be used as Decision Support System (DSS for precise selection of sprayer working parameters to adapt to local field scenarios. Five nozzle types (designs were evaluated across their complete range of orifice size (flow rate* and spray pressures using a response surface experimental design. Several of the models showed high level fits of the modeled to the measured data while several did not as a result of the lack of significant effect from either orifice size (flow rate* or spray pressure. The computational models were integrated into a spreadsheet based user interface for ease of use. The proposed experimental design provides for efficient nozzle evaluations and development of computational models that allow for the determination of droplet size spectrum and spraying classification for any combination of a given nozzle’s operating settings. The proposed DSS will allow for the ready assessment and modification of a sprayers performance based on the operational settings, to ensure the application is made following recommendations in plant protection products (PPP labels.

  19. Concentrating solar power plant investment and operation decisions under different price and support mechanisms

    International Nuclear Information System (INIS)

    Kost, Christoph; Flath, Christoph M.; Möst, Dominik


    The dispatch opportunities provided by storage-enhanced Concentrating Solar Power (CSP) plants have direct implications on the investment decisions as not only nameplate capacity but also the storage capacity and the solar multiple play a crucial role for the viability of the plant investment. By integrating additional technical aspects and operation strategies, this paper extends the optimization model proposed by Madaeni et al., How Thermal Energy Storage Enhances the Economic Viability of Concentrating Solar Power. Using a mixed integer maximization approach the paper yields both the optimal layout decision and the operation of CSP plants. Subsequently, the economic value of CSP storage is analyzed via energy modeling of a Spanish plant location under the respective wholesale market prices as well as the local feed-in tariff. The analysis shows that investment incentives for CSP plants with storage need to appropriately account for the interdependency between the price incentives and the plant operating strategy. As the resulting revenue characteristics influence the optimal size of solar field and storage differing operating strategies also give rise to differing optimal plant layouts. Most noteworthy, the current Spanish support scheme offers only limited incentives for larger thermal storage capacity. - Highlights: • Dispatch opportunities of CSP have direct implications on both investment and operational decisions. • Valuation approach with a single mixed integer maximization problem. • Profitability of CSP plants under the premium feed-in tariff in Spain was assessed. • Layout decision and storage size are influenced by remuneration scheme. • Discuss alternative remuneration schemes for “dispatchable” RE technologies

  20. Biotechnological production of vanillin using immobilized enzymes. (United States)

    Furuya, Toshiki; Kuroiwa, Mari; Kino, Kuniki


    Vanillin is an important and popular plant flavor, but the amount of this compound available from plant sources is very limited. Biotechnological methods have high potential for vanillin production as an alternative to extraction from plant sources. Here, we report a new approach using immobilized enzymes for the production of vanillin. The recently discovered oxygenase Cso2 has coenzyme-independent catalytic activity for the conversion of isoeugenol and 4-vinylguaiacol to vanillin. Immobilization of Cso2 on Sepabeads EC-EA anion-exchange carrier conferred enhanced operational stability enabling repetitive use. This immobilized Cso2 catalyst allowed 6.8mg yield of vanillin from isoeugenol through ten reaction cycles at a 1mL scale. The coenzyme-independent decarboxylase Fdc, which has catalytic activity for the conversion of ferulic acid to 4-vinylguaiacol, was also immobilized on Sepabeads EC-EA. We demonstrated that the immobilized Fdc and Cso2 enabled the cascade synthesis of vanillin from ferulic acid via 4-vinylguaiacol with repetitive use of the catalysts. This study is the first example of biotechnological production of vanillin using immobilized enzymes, a process that provides new possibilities for vanillin production. Copyright © 2016 Elsevier B.V. All rights reserved.

  1. A logic flowgraph based concept for decision support and management of nuclear plant operation

    International Nuclear Information System (INIS)

    Guarro, S.B.


    In the US the evolution of automated decision support tools for plant operators has spanned from ''event-oriented'' diagnostic systems to ''symptom-oriented'' computer-based emergency operating procedures. A problem common to both kind of systems is in the initial level of effort required for development of the associated models and software. In the following we will discuss some of the general issues that arise in the development and application of these decision-support systems. We will also propose and discuss an approach founded on the application of an event diagnosis and plant stabilization philosophy. This approach is based on the use of logic flowgraph process-oriented models - arranged in a modular architecture and developed with the aid of an expert-system model builder - as a possible means of achieving the development of an automated and integrated plant management system. This approach should allow the developer to achieve a high process recovery and management capability with a focused and controlled expenditure of development time and resources

  2. The role of science in support of operational decision-making during oil spills

    International Nuclear Information System (INIS)

    Walker, A.H.; Robinson, J.H.


    The potential for environmental damage is the principal rationale for responding to oil spills in the United States, and most other countries. Numerous factors influence response decisions regarding containment, cleanup and treatment operations. Important influences which drive how decisions will be made include politics, economics, environmental concerns, public relations, and aesthetics. A common misperceptions that scientific information cannot be generated on a real-time basis, that is, that scientific studies generally require more time to conduct than the spill response time frame permits. This paper discusses how to organize a scientific program in support of operational decision-making during oil spills, using NOAA's Scientific Support Team as an illustrative example. The paper also describes various types of scientific activities, including use of types of off-the-shelf technology and instrumentation, which can be conducted at the time of a spill, such as those implemented during the EXXON VALDEZ. Lastly, the paper provides guidance on how to generate and mange valid scientific information in ways that are relevant to timely response decision-making

  3. The design and validation of advanced operator support systems for a role in plant safety

    International Nuclear Information System (INIS)

    Hughes, G.


    Advanced operator support systems have the potential of making a significant contribution to plant safety. This note reviews the different support functions required, the specification of performance criteria and possible approaches for system validation. The importance of the different functions that can be provided is related to the stage of the accident sequence. Also, because of the restricted reliability of any single system, subdivision of the systems is suggested in order to make the maximum contribution at a number of sequential stages. In this way it should be possible to make a significant claim for reduced operator error over the full accident progression, from incipient fault to disaster. The use of performance criteria currently associated with the classification of safety-grade trip systems (e.g. detection failure probability) would seem to provide a sound basis for validation. The validation of systems is seen as a significant task which will rely on the use of design and training-simulator data together with specific plant measurements. Expert systems appear to present particular problems for validation. (author)

  4. Development and evaluation of a movie-centric multimedia system for supporting operation and maintenance 'K-SHOW'

    International Nuclear Information System (INIS)

    Kage, Yoshiko; Kubono, Norimitsu


    The fact that operators in the power plants and the power networks needed On the Job Training (OJT) opportunities and adequate materials was one of the most important factors that improved human performance. In this research, we have developed, 'Movie-centric Multimedia System', or 'K-SHOW', for supporting operation and maintenance in order to improve their skills and knowledge. Operators could author the movies with texts, symbols, and so forth interactively and flexibly and could view it on the CRT screen. Operators could learn expert' know-how and check the operations before working actual operation. Operators rated this system as a highly useful tool of transfer for supporting operation and maintenance in their workplaces. (author)

  5. The costly benefits of opposing agricultural biotechnology. (United States)

    Apel, Andrew


    Rigorous application of a simple definition of what constitutes opposition to agricultural biotechnology readily encompasses a wide array of key players in national and international systems of food production, distribution and governance. Even though the sum of political and financial benefits of opposing agricultural biotechnology appears vastly to outweigh the benefits which accrue to providers of agricultural biotechnology, technology providers actually benefit from this opposition. If these barriers to biotechnology were removed, subsistence farmers still would not represent a lucrative market for improved seed. The sum of all interests involved ensures that subsistence farmers are systematically denied access to agricultural biotechnology. Copyright © 2010 Elsevier B.V. All rights reserved.

  6. Unattended network operations technology assessment study. Technical support for defining advanced satellite systems concepts (United States)

    Price, Kent M.; Holdridge, Mark; Odubiyi, Jide; Jaworski, Allan; Morgan, Herbert K.


    The results are summarized of an unattended network operations technology assessment study for the Space Exploration Initiative (SEI). The scope of the work included: (1) identified possible enhancements due to the proposed Mars communications network; (2) identified network operations on Mars; (3) performed a technology assessment of possible supporting technologies based on current and future approaches to network operations; and (4) developed a plan for the testing and development of these technologies. The most important results obtained are as follows: (1) addition of a third Mars Relay Satellite (MRS) and MRS cross link capabilities will enhance the network's fault tolerance capabilities through improved connectivity; (2) network functions can be divided into the six basic ISO network functional groups; (3) distributed artificial intelligence technologies will augment more traditional network management technologies to form the technological infrastructure of a virtually unattended network; and (4) a great effort is required to bring the current network technology levels for manned space communications up to the level needed for an automated fault tolerance Mars communications network.

  7. The systems integration operations/logistics model as a decision-support tool

    International Nuclear Information System (INIS)

    Miller, C.; Vogel, L.W.; Joy, D.S.


    Congress has enacted legislation specifying Yucca Mountain, Nevada, for characterization as the candidate site for the disposal of spent fuel and high-level wastes and has authorized a monitored retrievable storage (MRS) facility if one is warranted. Nevertheless, the exact configuration of the facilities making up the Federal Waste Management System (FWMS) was not specified. This has left the Office of Civilian Radioactive Waste Management (OCRWM) the responsibility for assuring the design of a safe and reliable disposal system. In order to assist in the analysis of potential configuration alternatives, operating strategies, and other factors for the FWMS and its various elements, a decision-support tool known as the systems integration operations/logistics model (SOLMOD) was developed. SOLMOD is a discrete event simulation model that emulates the movement and interaction of equipment and radioactive waste as it is processed through the FWMS - from pickup at reactor pools to emplacement. The model can be used to measure the impacts of different operating schedules and rules, system configurations, and equipment and other resource availabilities on the performance of processes comprising the FWMS and how these factors combine to determine overall system performance. SOLMOD can assist in identifying bottlenecks and can be used to assess capacity utilization of specific equipment and staff as well as overall system resilience

  8. Contracting out Support Services in Future Expeditionary Operations: Learning from the Afghan Experience

    Directory of Open Access Journals (Sweden)

    Christopher Kinsey


    Full Text Available As with the US led Coalition war in Iraq, the war in Afghanistan has seen an unprecedented number of private contractors being utilised in support of military operations in the country. In the case of the United States government for example, over half of its personnel in Afghanistan and Iraq are contract employees, while the same figure in the UK stands at 30 per cent and is set to increase in the coming years. This level of contractor involvement in the ‘War on Terror’ is not inconsequential. Indeed, their contribution to military operations is so large they are now able to influence NATO’s counter-insurgency operations and thus its overall strategy for fighting the Taliban and Al-Qaeda. Importantly, such involvement can be both beneficial and/or detrimental. This article first sets out to explore how NATO came to rely on so many contractors in Afghanistan and the risks this involves for the ‘War on Terror’.

  9. Operational data products to support phenological research and applications at local to continental scales (United States)

    Weltzin, J. F.


    Phenological data from a variety of platforms - across a range of spatial and temporal scales - are required to support research, natural resource management, and policy- and decision-making in a changing world. Observational and modeled phenological data, especially when integrated with associated biophysical data (e.g., climate, land-use/land-cover, hydrology) has great potential to provide multi-faceted information critical to decision support systems, vulnerability and risk assessments, change detection applications, and early-warning and forecasting systems for natural and modified ecosystems. The USA National Phenology Network (USA-NPN; is a national-scale science and monitoring initiative focused on understanding the drivers and feedback effects of phenological variation in changing environments. The Network maintains a centralized database of over 10M ground-based observations of plants and animals for 1954-present, and leverages these data to produce operational data products for use by a variety of audiences, including researchers and resource managers. This presentation highlights our operational data products, including the tools, maps, and services that facilitate discovery, accessibility and usability of integrated phenological information. We describe (1) the data download tool, a customizable GUI that provides geospatially referenced raw, bounded or summarized organismal and climatological data and associated metadata (including calendars, time-series curves, and XY graphs), (2) the visualization tool, which provides opportunities to explore, visualize and export or download both organismal and modeled (gridded) products at daily time-steps and relatively fine spatial resolutions ( 2.5 km to 4 km) for the period 1980 to 6 days into the future, and (3) web services that enable custom query and download of map, feature and cover services in a variety of standard formats. These operational products facilitate scaling of integrated

  10. An Evolutionary Complex Systems Decision-Support Tool for the Management of Operations

    International Nuclear Information System (INIS)

    Baldwin, J S; Allen, P M; Ridgway, K


    This research aimed to add both to the development of complex systems thinking in the subject area of Operations and Production Management and to the limited number of applications of computational models and simulations from the science of complex systems. The latter potentially offer helpful decision-support tools for operations and production managers. A mechanical engineering firm was used as a case study where a combined qualitative and quantitative methodological approach was employed to extract the required data from four senior managers. Company performance measures as well as firm technologies, practices and policies, and their relation and interaction with one another, were elicited. The data were subjected to an evolutionary complex systems model resulting in a series of simulations. The findings included both reassuring and some unexpected results. The simulation based on the CEO's opinions led the most cohesive and synergistic collection of practices describing the firm, closely followed by the Marketing and R and D Managers. The Manufacturing Manager's responses led to the most extreme evolutionary trajectory where the integrity of the entire firm came into question particularly when considering how employees were utilised. By drawing directly from the opinions and views of managers rather than from logical 'if-then' rules and averaged mathematical representations of agents that characterise agent-based and other self-organisational models, this work builds on previous applications by capturing a micro-level description of diversity and a learning effect that has been problematical not only in terms of theory but also in application. This approach can be used as a decision-support tool for operations and other managers providing a forum with which to explore a) the strengths, weaknesses and consequences of different decision-making capacities within the firm; b) the introduction of new manufacturing technologies, practices and policies; and, c) the

  11. An Evolutionary Complex Systems Decision-Support Tool for the Management of Operations (United States)

    Baldwin, J. S.; Allen, P. M.; Ridgway, K.


    This research aimed to add both to the development of complex systems thinking in the subject area of Operations and Production Management and to the limited number of applications of computational models and simulations from the science of complex systems. The latter potentially offer helpful decision-support tools for operations and production managers. A mechanical engineering firm was used as a case study where a combined qualitative and quantitative methodological approach was employed to extract the required data from four senior managers. Company performance measures as well as firm technologies, practices and policies, and their relation and interaction with one another, were elicited. The data were subjected to an evolutionary complex systems model resulting in a series of simulations. The findings included both reassuring and some unexpected results. The simulation based on the CEO's opinions led the most cohesive and synergistic collection of practices describing the firm, closely followed by the Marketing and R&D Managers. The Manufacturing Manager's responses led to the most extreme evolutionary trajectory where the integrity of the entire firm came into question particularly when considering how employees were utilised. By drawing directly from the opinions and views of managers rather than from logical 'if-then' rules and averaged mathematical representations of agents that characterise agent-based and other self-organisational models, this work builds on previous applications by capturing a micro-level description of diversity and a learning effect that has been problematical not only in terms of theory but also in application. This approach can be used as a decision-support tool for operations and other managers providing a forum with which to explore a) the strengths, weaknesses and consequences of different decision-making capacities within the firm; b) the introduction of new manufacturing technologies, practices and policies; and, c) the

  12. The rise (and decline?) of biotechnology. (United States)

    Kinch, Michael S


    Since the 1970s, biotechnology has been a key innovator in drug development. An analysis of FDA-approved therapeutics demonstrates pharmaceutical companies outpace biotechs in terms of new approvals but biotechnology companies are now responsible for earlier-stage activities (patents, INDs or clinical development). The number of biotechnology organizations that contributed to an FDA approval began declining in the 2000s and is at a level not seen since the 1980s. Whereas early biotechnology companies had a decade from first approval until acquisition, the average acquisition of a biotechnology company now occurs months before their first FDA approval. The number of hybrid organizations that arise when pharmaceutical companies acquire biotechnology is likewise declining, raising questions about the sustainability of biotechnology. Copyright © 2014 Elsevier Ltd. All rights reserved.

  13. The role of casein in supporting the operation of surface bound kinesin

    Directory of Open Access Journals (Sweden)

    Hancock William O


    Full Text Available Abstract Microtubules and associated motor proteins such as kinesin are envisioned for applications such as bioseparation and molecular sorting to powering hybrid synthetic mechanical devices. One of the challenges in realizing such systems is retaining motor functionality on device surfaces. Kinesin motors adsorbed onto glass surfaces lose their functionality or ability to interact with microtubules if not adsorbed with other supporting proteins. Casein, a milk protein, is commonly used in microtubule motility assays to preserve kinesin functionality. However, the mechanism responsible for this preservation of motor function is unknown. To study casein and kinesin interaction, a series of microtubule motility assays were performed where whole milk casein, or its αs1 and αs2, β or κ subunits, were introduced or omitted at various steps of the motility assay. In addition, a series of epifluorescence and total internal reflection microscopy (TIRF experiments were conducted where fluorescently labeled casein was introduced at various steps of the motility assay to assess casein-casein and casein-glass binding dynamics. From these experiments it is concluded that casein forms a bi-layer which supports the operation of kinesin. The first tightly bound layer of casein mainly performs the function of anchoring the kinesin while the second more loosely bound layer of casein positions the head domain of the kinesin to more optimally interact with microtubules. Studies on individual casein subunits indicate that β casein was most effective in supporting kinesin functionality while κ casein was found to be least effective.

  14. Aerodynamic journal bearing with a flexible, damped support operating at 7.2 million DN (United States)

    Waumans, Tobias; Peirs, Jan; Al-Bender, Farid; Reynaerts, Dominiek


    This paper reports on the design, development and experimental validation of an aerodynamic journal bearing with a flexible, damped support operating at speeds up to 1.2 million rpm (= 7.2 million DN). In terms of the DN-number, this achievement represents to our knowledge a record for an air bearing of the self-acting type. Stabilization by means of a flexible, damped support therefore proves to be a promising solution to the dynamic stability problem of high-speed gas bearings. In order to select the support parameters in an optimal way, a stability study is performed leading to the formulation of a series of dimensionless design guidelines. The proposed implementation, which makes use of elastomeric O-rings in combination with a tunable squeeze-film damper, is discussed in detail. A method for the manufacturing of miniature bearing bushes with a wave-shaped film height profile is outlined. Experiments up to 683 280 rpm are performed with an air-driven turbine and up to 1203 000 rpm with a helium-driven turbine. Deceleration experiments are conducted in order to obtain an estimation of the frictional losses of the system.

  15. Review of computational fluid dynamics applications in biotechnology processes. (United States)

    Sharma, C; Malhotra, D; Rathore, A S


    Computational fluid dynamics (CFD) is well established as a tool of choice for solving problems that involve one or more of the following phenomena: flow of fluids, heat transfer,mass transfer, and chemical reaction. Unit operations that are commonly utilized in biotechnology processes are often complex and as such would greatly benefit from application of CFD. The thirst for deeper process and product understanding that has arisen out of initiatives such as quality by design provides further impetus toward usefulness of CFD for problems that may otherwise require extensive experimentation. Not surprisingly, there has been increasing interest in applying CFD toward a variety of applications in biotechnology processing in the last decade. In this article, we will review applications in the major unit operations involved with processing of biotechnology products. These include fermentation,centrifugation, chromatography, ultrafiltration, microfiltration, and freeze drying. We feel that the future applications of CFD in biotechnology processing will focus on establishing CFD as a tool of choice for providing process understanding that can be then used to guide more efficient and effective experimentation. This article puts special emphasis on the work done in the last 10 years. © 2011 American Institute of Chemical Engineers

  16. Human Factors and Technical Considerations for a Computerized Operator Support System Prototype

    Energy Technology Data Exchange (ETDEWEB)

    Ulrich, Thomas Anthony [Idaho National Lab. (INL), Idaho Falls, ID (United States); Lew, Roger Thomas [Idaho National Lab. (INL), Idaho Falls, ID (United States); Medema, Heather Dawne [Idaho National Lab. (INL), Idaho Falls, ID (United States); Boring, Ronald Laurids [Idaho National Lab. (INL), Idaho Falls, ID (United States); Thomas, Kenneth David [Idaho National Lab. (INL), Idaho Falls, ID (United States)


    A prototype computerized operator support system (COSS) has been developed in order to demonstrate the concept and provide a test bed for further research. The prototype is based on four underlying elements consisting of a digital alarm system, computer-based procedures, PI&D system representations, and a recommender module for mitigation actions. At this point, the prototype simulates an interface to a sensor validation module and a fault diagnosis module. These two modules will be fully integrated in the next version of the prototype. The initial version of the prototype is now operational at the Idaho National Laboratory using the U.S. Department of Energy’s Light Water Reactor Sustainability (LWRS) Human Systems Simulation Laboratory (HSSL). The HSSL is a full-scope, full-scale glass top simulator capable of simulating existing and future nuclear power plant main control rooms. The COSS is interfaced to the Generic Pressurized Water Reactor (gPWR) simulator with industry-typical control board layouts. The glass top panels display realistic images of the control boards that can be operated by touch gestures. A section of the simulated control board was dedicated to the COSS human-system interface (HSI), which resulted in a seamless integration of the COSS into the normal control room environment. A COSS demonstration scenario has been developed for the prototype involving the Chemical & Volume Control System (CVCS) of the PWR simulator. It involves a primary coolant leak outside of containment that would require tripping the reactor if not mitigated in a very short timeframe. The COSS prototype presents a series of operator screens that provide the needed information and soft controls to successfully mitigate the event.

  17. Verification of Ensemble Forecasts for the New York City Operations Support Tool (United States)

    Day, G.; Schaake, J. C.; Thiemann, M.; Draijer, S.; Wang, L.


    The New York City water supply system operated by the Department of Environmental Protection (DEP) serves nine million people. It covers 2,000 square miles of portions of the Catskill, Delaware, and Croton watersheds, and it includes nineteen reservoirs and three controlled lakes. DEP is developing an Operations Support Tool (OST) to support its water supply operations and planning activities. OST includes historical and real-time data, a model of the water supply system complete with operating rules, and lake water quality models developed to evaluate alternatives for managing turbidity in the New York City Catskill reservoirs. OST will enable DEP to manage turbidity in its unfiltered system while satisfying its primary objective of meeting the City's water supply needs, in addition to considering secondary objectives of maintaining ecological flows, supporting fishery and recreation releases, and mitigating downstream flood peaks. The current version of OST relies on statistical forecasts of flows in the system based on recent observed flows. To improve short-term decision making, plans are being made to transition to National Weather Service (NWS) ensemble forecasts based on hydrologic models that account for short-term weather forecast skill, longer-term climate information, as well as the hydrologic state of the watersheds and recent observed flows. To ensure that the ensemble forecasts are unbiased and that the ensemble spread reflects the actual uncertainty of the forecasts, a statistical model has been developed to post-process the NWS ensemble forecasts to account for hydrologic model error as well as any inherent bias and uncertainty in initial model states, meteorological data and forecasts. The post-processor is designed to produce adjusted ensemble forecasts that are consistent with the DEP historical flow sequences that were used to develop the system operating rules. A set of historical hindcasts that is representative of the real-time ensemble

  18. Agriculture and bio-technology

    Energy Technology Data Exchange (ETDEWEB)

    Yamaguchi, Hikoyuki


    The Japanese agriculture is going to be influenced by bio-technology. New style of production will be introduced through the entrance of other type of enterprises causing considerable change in agricultural fields. Bio-technology is a technology which utmost utilizes the functions of the living organism. Its practical target is to manifestate a new function by deliberately endowing it to an organism. Major technique is gene manipulation, tissue culture and utilization of microorganism and cells as well as the utilization of the biomass resources and a production means in the vegetable plant using nutricious solution. This report especially describes the following matters. Recombinant DNA (Super mouse, etc). Cell fusion (Monoclonal antigen, etc). Nucleus transplantation. Chromosome manipulation (Creation of tripoloid, etc). tissue culture (Growing of virus-free seedling, etc). Production of useful substances. Biomass (Forestry, Ocean, Livestock). (2 figs, 3 tabs, 12 refs)

  19. New challenges in microalgae biotechnology. (United States)

    Valverde, Federico; Romero-Campero, Francisco J; León, Rosa; Guerrero, Miguel G; Serrano, Aurelio


    Photosynthetic protists, also called microalgae, have been systematically studied for more than a century. However, only recently broad biotechnological applications have fostered a novel wave of research on their potentialities as sustainable resources of renewable energy as well as valuable industrial and agro-food products. At the recent VII European Congress of Protistology held in Seville, three outstanding examples of different research strategies on microalgae with biotechnological implications were presented, which suggested that integrative approaches will produce very significant advances in this field in the next future. In any case, intense research and the application of systems biology and genetic engineering techniques are absolutely essential to reach the full potential of microalgae as cell-factories of bio-based products and, therefore, could contribute significantly to solve the problems of biosustainability and energy shortage. Copyright © 2016 Elsevier GmbH. All rights reserved.

  20. ASUD2- decision support system on Dnieper reservoirs operations taking into account environmental priorities (United States)

    Iritz, L.; Zheleznyak, M.; Dvorzhak, A.; Nesterov, A.; Zaslavsky, A.


    On the European continent the Dnieper is the third largest river basin (509000 The Ukrainian part of the drainage basin is 291 400 The cascade of 6 reservoirs, that have capacity from 2.5 to 18 comprises the entire reach of Dnieper River in Ukraine, redistributes the water regime in time. As a result, 17-18 cub. km water can be used, 50% for hydropower production, 30% for agriculture and up to 18% for municipal water supply. The water stress, the pollution load, the insufficient technical conditions require a lot of effort in the water management development. In order to achieve optimal use of water recourses in the Dnieper River basin, it is essential to develop strategies both for the long-term perspective (planning) as well as for the short-term perspective (operation). The Dnieper River basin must be seen as complex of the natural water resources, as well as the human system (water use, social and economic intercourse). In the frame of the project, supported by the Swedish International Development Cooperation Agency (SIDA) the software tool ASUD2 is developed to support reservoir operations provided by the State Committee of Ukraine on Water Management and by the Joint River Commission. ASUD2 includes multicriteria optimization engine that drives the reservoir water balamce models and box models of water quality. A system of supplementary (off-line) tools support more detailed analyses of the water quality parameters of largest reservoirs (Kachovka and Kremechug). The models AQUATOX and WASP ( in the developed 3-D version) are used for these purposes. The Integrated Database IDB-ASUD2 supplies the information such as state of the all reservoirs, hydrological observations and predictions, water demands, measured water quality parameters. ASUD2 is able to give the following information on an operational basis. : - recommended dynamics of the water elevation during the water allocation planning period in all reservoirs calculated on the

  1. [Biotechnological aspects in "loco" larvae]. (United States)

    Inestrosa, N C; Labarca, R; Perelman, A; Campos, E O; Araneda, R; González, M; Brandan, E; Sánchez, J P; González-Plaza, R


    The biology of planktotrophic larvae of Concholepas concholepas is the main bottleneck towards developing biotechnologies to rear this muricid. Data concerning planktonic larvae development, diets and environmental signals triggering larval settlement and recruitment is scarce. We have begun the study of the molecular and cell biology of embryos, larvae and recruits having as a final goal, the development of appropriate biotechnologies to rear this gastropod. First, an inverse ratio between BuChE and AChE enzyme activities was established. This ratio may be a precise developmental marker for this species. Second, for the first time a phosphoinositide related regulatory pathway is reported in a muricid, opening a new approach to the biotechnological management of larvae. Third, the relation between sulfate in sea water and larval motility was studied. Concentrations below 125 microM sulfate decreases larval motility. The sulfate is incorporated in proteoglycans which participate in different developmental phenomena. Lastly, a genomic Concholepas concholepas DNA sequence, similar to that of a human growth hormone probe was detected. This is very interesting since growth factors are key molecules during development, growth and are involved in food conversion rates in fish and also, in a variety of marine invertebrates.

  2. Interface of nuclear and biotechnologies

    International Nuclear Information System (INIS)

    Castro Diaz-Balart, F.


    Addressing nuclear and biotechnologies in the International Year of Physics should begin by highlighting the important role that this science has played in the development of both branches of science and technologies. The first as a direct consequence of the Theory of Relativity, the further was considerably influenced by Schroedinger's remarks that there must be a code of some kind that allowed molecules in cells to carry information, making a connection between genes and proteins. Both, like any highly technical endeavor, have also in common that the use of technologies demands a vast accumulation of knowledge, i.e. volumes of scientific research, engineering analysis, strict regulatory controls and a huge amount of information combined with a complex assortment of people with the required educational background, expertise and skills to master it. This presentation briefly explores the ways in which nuclear technology has been used in the last decades of the 20th century in the field of biomedicine applications, which includes the use of radiation to obtain accurate images as well as in diagnosis and therapy. The paper looks at the present prospects of some nuclear methods and instrumentation in the so-called Red biotechnology and its genetically engineered therapeutic agents and diagnostic tests as well as some related perspectives in the field of bioinformatics. As an example of biotechnology being successfully applied to health problems in developing countries the presentation gives an outlook of relevant Cuban achievements in this field. (author)

  3. Artificial Intelligence (AI), Operations Research (OR), and Decision Support Systems (DSS): A conceptual framework (United States)

    Parnell, Gregory S.; Rowell, William F.; Valusek, John R.


    In recent years there has been increasing interest in applying the computer based problem solving techniques of Artificial Intelligence (AI), Operations Research (OR), and Decision Support Systems (DSS) to analyze extremely complex problems. A conceptual framework is developed for successfully integrating these three techniques. First, the fields of AI, OR, and DSS are defined and the relationships among the three fields are explored. Next, a comprehensive adaptive design methodology for AI and OR modeling within the context of a DSS is described. These observations are made: (1) the solution of extremely complex knowledge problems with ill-defined, changing requirements can benefit greatly from the use of the adaptive design process, (2) the field of DSS provides the focus on the decision making process essential for tailoring solutions to these complex problems, (3) the characteristics of AI, OR, and DSS tools appears to be converging rapidly, and (4) there is a growing need for an interdisciplinary AI/OR/DSS education.

  4. System analysis for the Huntsville Operation Support Center distributed computer system (United States)

    Ingels, F. M.


    A simulation model of the NASA Huntsville Operational Support Center (HOSC) was developed. This simulation model emulates the HYPERchannel Local Area Network (LAN) that ties together the various computers of HOSC. The HOSC system is a large installation of mainframe computers such as the Perkin Elmer 3200 series and the Dec VAX series. A series of six simulation exercises of the HOSC model is described using data sets provided by NASA. The analytical analysis of the ETHERNET LAN and the video terminals (VTs) distribution system are presented. An interface analysis of the smart terminal network model which allows the data flow requirements due to VTs on the ETHERNET LAN to be estimated, is presented.

  5. System analysis for the Huntsville Operational Support Center distributed computer system (United States)

    Ingels, F. M.; Mauldin, J.


    The Huntsville Operations Support Center (HOSC) is a distributed computer system used to provide real time data acquisition, analysis and display during NASA space missions and to perform simulation and study activities during non-mission times. The primary purpose is to provide a HOSC system simulation model that is used to investigate the effects of various HOSC system configurations. Such a model would be valuable in planning the future growth of HOSC and in ascertaining the effects of data rate variations, update table broadcasting and smart display terminal data requirements on the HOSC HYPERchannel network system. A simulation model was developed in PASCAL and results of the simulation model for various system configuraions were obtained. A tutorial of the model is presented and the results of simulation runs are presented. Some very high data rate situations were simulated to observe the effects of the HYPERchannel switch over from contention to priority mode under high channel loading.

  6. Transportation system modeling and simulation in support of logistics and operations

    International Nuclear Information System (INIS)

    Yoshimura, R.H.; Kjeldgaard, E.A.; Turnquist, M.A.; List, G.F.


    Effective management of DOE's transportation operations requires better data than are currently available, a more integrated management structure for making transportation decisions, and decision support tools to provide needed analysis capabilities. This paper describes a vision of an advanced logistics management system for DOE, and the rationale for developing improved modeling and simulation capability as an integral part of that system. The authors illustrate useful types of models through four examples, addressing issues of transportation package allocation, fleet sizing, routing/scheduling, and emergency responder location. The overall vision for the advanced logistics management system, and the specific examples of potential capabilities, provide the basis for a conclusion that such a system would meet a critical DOE need in the area of radioactive material and waste transportation

  7. Transportation system modeling and simulation in support of logistics and operations

    International Nuclear Information System (INIS)

    Yoshimura, R.H.; Kjeldgaard, E.A.; Turnquist, M.A.; List, G.F.


    Effective management of DOE's transportation operations requires better data than are currently available, a more integrated management structure for making transportation decisions, and decision support tools to provide needed analysis capabilities. This paper describes a vision of an advanced logistics management system for DOE, and the rationale for developing improved modeling and simulation capability as an integral part of that system. We illustrate useful types of models through four examples, addressing issues of transportation package allocation, fleet sizing, routing/Scheduling, and emergency responder location. The overall vision for the advanced logistics management system, and the specific examples of potential capabilities, provide the basis for a conclusion that such a system would meet a critical DOE need in the area of radioactive material and waste transportation. (authors)

  8. Validating cognitive support for operators of complex human-machine systems

    International Nuclear Information System (INIS)

    O'Hara, J.; Wachtel, J.


    Modem nuclear power plants (NPPs) are complex systems whose performance is the result of an intricate interaction of human and system control. A complex system may be defined as one which supports a dynamic process involving a large number of elements that interact in many different ways. Safety is addressed through defense-in-depth design and preplanning; i.e., designers consider the types of failures that are most likely to occur and those of high consequence, and design their solutions in advance. However, complex interactions and their failure modes cannot always be anticipated by the designer and may be unfamiliar to plant personnel. These situations may pose cognitive demands on plant personnel, both individually and as a crew. Other factors may contribute to the cognitive challenges of NPP operation as well, including hierarchal processes, dynamic pace, system redundancy and reliability, and conflicting objectives. These factors are discussed in this paper

  9. Establishing a group of endpoints to support collective operations without specifying unique identifiers for any endpoints (United States)

    Archer, Charles J.; Blocksom, Michael A.; Ratterman, Joseph D.; Smith, Brian E.; Xue, Hanghon


    A parallel computer executes a number of tasks, each task includes a number of endpoints and the endpoints are configured to support collective operations. In such a parallel computer, establishing a group of endpoints receiving a user specification of a set of endpoints included in a global collection of endpoints, where the user specification defines the set in accordance with a predefined virtual representation of the endpoints, the predefined virtual representation is a data structure setting forth an organization of tasks and endpoints included in the global collection of endpoints and the user specification defines the set of endpoints without a user specification of a particular endpoint; and defining a group of endpoints in dependence upon the predefined virtual representation of the endpoints and the user specification.

  10. Low-energy beam transport studies supporting the spallation neutron source 1-MW beam operation. (United States)

    Han, B X; Kalvas, T; Tarvainen, O; Welton, R F; Murray, S N; Pennisi, T R; Santana, M; Stockli, M P


    The H(-) injector consisting of a cesium enhanced RF-driven ion source and a 2-lens electrostatic low-energy beam transport (LEBT) system supports the spallation neutron source 1 MW beam operation with ∼38 mA beam current in the linac at 60 Hz with a pulse length of up to ∼1.0 ms. In this work, two important issues associated with the low-energy beam transport are discussed: (1) inconsistent dependence of the post-radio frequency quadrupole accelerator beam current on the ion source tilt angle and (2) high power beam losses on the LEBT electrodes under some off-nominal conditions compromising their reliability.

  11. Proposal for the award of an industrial support contract for operation of the CERN telephone system

    CERN Document Server


    This document concerns the award of an industrial support contract for operation of the CERN telephone system. Following a market survey carried out among 22 firms in eight Member States, a call for tenders (IT-2655/ST) was sent on 27 August 1999 to three firms and two consortia in four Member States. By the closing date, CERN had received three tenders from one firm and two consortia in three Member States. The Finance Committee is invited to agree to the negotiation of a contract with the consortium MERROW (UK) ? DCS (CH) the lowest bidder, for an initial period of three years from 1st January 2000, for a total amount not exceeding 850 000 Swiss francs, not subject to revision until 31 December 2000. The contract will include an option for two one-year extensions beyond the initial three-year period.

  12. Computer systems in the operation, maintenance and technical support of Loviisa NPS

    International Nuclear Information System (INIS)

    Tiitinen, M.


    A description is given of how the Loviisa nuclear power plant has utilized computers in many ways in the operation, maintenance, technical support and in other functions at the plant. The evolution of the computer system can be divided into the following phases: plant commissioning (1975-80), maintenance systems development (1981-84), second generation systems take-over (1985-90) and workstation client/server systems and PC's proliferation (1991->). A short description is given of the main systems at the Loviisa plant using computers, i.e. process computer systems, the plant information system, training simulator, vibration monitoring, laboratory computer systems, PC and workstation applications. (Z.S.) 4 refs

  13. Rapid Operational Access and Maneuver Support (ROAMS) Platform for Improved Military Logistics Lines of Communication and Operational Vessel Routing (United States)


    Platform for Improved Military Logistics Lines of Communication and Operational Vessel Routing by Drew Loney, Kimberly Pevey, Jennifer McAlpin...classified into two types of activities: logistics and operational. Logistics activities are concerned with the establishment of lines of communication...obstacles such as shoals, reefs, and wreckage. The qualitative nature of the military logistics planning process causes direct comparison of LOC to be

  14. DART: Tools and Support for Ensemble Data Assimilation Research, Operations, and Education (United States)

    Anderson, J. L.; Raeder, K.; Hoar, T. J.; Collins, N.; Kershaw, H.; Romine, G. S.; Liu, H.; Mizzi, A. P.; Lei, L.; Chatterjee, A.; Karspeck, A. R.; Pedatella, N. M.


    The Data Assimilation Research Testbed (DART) is a community facility for ensemble data assimilation developed and supported by the National Center for Atmospheric Research. DART provides a comprehensive suite of software, documentation, examples and tutorials that can be used for ensemble data assimilation research, operations, and education. Scientists and software engineers from the Data Assimilation Research Section at NCAR are available to actively support DART users who want to use existing DART products or develop their own new applications. Current DART users range from university professors teaching data assimilation, to individual graduate students working with simple models, through national laboratories doing operational prediction with large state-of-the-art models. DART runs efficiently on many computational platforms ranging from laptops through thousands of cores on the newest supercomputers. This poster focuses on recent developments for coupled data assimilation with DART and NCAR's Community Earth System Model. DART interfaces to the Community Atmosphere Model (CAM), the Parallel Ocean Program (POP) and the Community Land Model (CLM) can now be used to do multiple component data assimilation with the fully-coupled CESM prediction model. The software innovations required to enable this are described. The latest results for ensemble assimilation experiments with each of the component models are presented along with initial comparisons to corresponding assimilations with the coupled model. A newly developed DART interface to the Whole Atmosphere Community Climate Model (WACCM) is now available. An overview of results of the relative value of assimilating tropospheric and middle atmosphere observations in WACCM is presented. DART is also used with many other types of geophysical models. Highlights of the latest results using DART with the Weather Research and Forecasting (WRF) model for springtime weather over the central United States are also

  15. An intellectual property sharing initiative in agricultural biotechnology: development of broadly accessible technologies for plant transformation. (United States)

    Chi-Ham, Cecilia L; Boettiger, Sara; Figueroa-Balderas, Rosa; Bird, Sara; Geoola, Josef N; Zamora, Pablo; Alandete-Saez, Monica; Bennett, Alan B


    The Public Intellectual Property Resource for Agriculture (PIPRA) was founded in 2004 by the Rockefeller Foundation in response to concerns that public investments in agricultural biotechnology benefiting developing countries were facing delays, high transaction costs and lack of access to important technologies due to intellectual property right (IPR) issues. From its inception, PIPRA has worked broadly to support a wide range of research in the public sector, in specialty and minor acreage crops as well as crops important to food security in developing countries. In this paper, we review PIPRA's work, discussing the failures, successes, and lessons learned during its years of operation. To address public sector's limited freedom-to-operate, or legal access to third-party rights, in the area of plant transformation, we describe PIPRA's patent 'pool' approach to develop open-access technologies for plant transformation which consolidate patent and tangible property rights in marker-free vector systems. The plant transformation system has been licensed and deployed for both commercial and humanitarian applications in the United States (US) and Africa, respectively. © 2012 The Authors. Plant Biotechnology Journal © 2012 Society for Experimental Biology, Association of Applied Biologists and Blackwell Publishing Ltd.

  16. Supporting MMT and Magellan Infrared Spectrograph: From Operations to a Science Ready Data Archive (United States)

    Chilingarian, I.; Moran, S.; Brown, W.; Conroy, M.; Fabricant, D.; Kurtz, M.; Matthews, A.; McLeod, B.; Roll, J.; Tokarz, S.


    The Telescope Data Center at Smithsonian Astrophysical Observatory supports observations and data flow from the optical telescopes of the Harvard-Smithsonian Center for Astrophysics. With a limited amount of manpower, we handle the entire process from instrument operations to the data archiving and scientific reduction, which allows us to avoid many of the difficulties other data centers encounter arising from the incompatibility of on the instrument and data processing sides. We use telescope control software and data reduction pipelines developed inside our unit which also helps us to ensure the consistency of data products at different stages of processing. Presently we are working on a data archive solution using PostgreSQL and GAVO DaCHS which will allow us to: (1) distribute the raw data to PIs on a timescale of days from observations; (2) feed the data reduction pipelines automatically; (3) distribute reduced science ready data to the PIs; (4) provide access to raw and processed data products using Virtual Observatory interfaces such as ObsTAP, SIAP, SSAP after the proprietary period of the data has expired; (5) maintain a searchable record of all astronomical sources observed by the instruments, along with a catalog of basic observing conditions and telescope/instrument status associated with each exposure. I will present the data archive prototypes for the MMIRS multi-object spectrograph. Our operations model can be scaled up and adopted by large optical observatories.

  17. Co-ordinated research programme on operator support systems in nuclear power plants. Working material

    International Nuclear Information System (INIS)


    In September 1991 the Co-ordinated Research Programme (CRP) on ''Operator Support Systems (OSSs) in Nuclear Power Plants'' was approved in the framework of the Project ''Man-Machine Interface Studies''. The main objective of the programme is to provide guidance and technology transfer in the development and implementation of OSSs. This includes the experience with man-machine interfaces and closely related issues such as control and instrumentation, the use of computers, and operator qualification. The first Co-ordinated Research Meeting held in Vienna, 13-16 October 1992, prepared a summary report which defined the tasks and the responsibilities of the CRP participants. A time schedule and future actions were also agreed upon at this meeting. The second meeting was held in Budapest, Hungary, from 5 to 8 October 1993 and was sponsored by the KFKI Atomic Energy Research Institute. The meeting reviewed the progress of the tasks defined by the first meeting, considered reports on national activities in the subject area, and agreed on time schedule and future actions. The present volume contains: (1) report prepared by the CRP meeting, (2) reports presented by the national delegates, and (3) CRP background and working plan. Refs, figs and tabs

  18. Functional Fault Model Development Process to Support Design Analysis and Operational Assessment (United States)

    Melcher, Kevin J.; Maul, William A.; Hemminger, Joseph A.


    A functional fault model (FFM) is an abstract representation of the failure space of a given system. As such, it simulates the propagation of failure effects along paths between the origin of the system failure modes and points within the system capable of observing the failure effects. As a result, FFMs may be used to diagnose the presence of failures in the modeled system. FFMs necessarily contain a significant amount of information about the design, operations, and failure modes and effects. One of the important benefits of FFMs is that they may be qualitative, rather than quantitative and, as a result, may be implemented early in the design process when there is more potential to positively impact the system design. FFMs may therefore be developed and matured throughout the monitored system's design process and may subsequently be used to provide real-time diagnostic assessments that support system operations. This paper provides an overview of a generalized NASA process that is being used to develop and apply FFMs. FFM technology has been evolving for more than 25 years. The FFM development process presented in this paper was refined during NASA's Ares I, Space Launch System, and Ground Systems Development and Operations programs (i.e., from about 2007 to the present). Process refinement took place as new modeling, analysis, and verification tools were created to enhance FFM capabilities. In this paper, standard elements of a model development process (i.e., knowledge acquisition, conceptual design, implementation & verification, and application) are described within the context of FFMs. Further, newer tools and analytical capabilities that may benefit the broader systems engineering process are identified and briefly described. The discussion is intended as a high-level guide for future FFM modelers.

  19. Strategies and Decision Support Systems for Integrating Variable Energy Resources in Control Centers for Reliable Grid Operations. Executive Summary

    Energy Technology Data Exchange (ETDEWEB)

    Jones, Lawrence E. [Alstom Grid, Inc., Washington, DC (United States)


    This is the executive summary for a report that provides findings from the field regarding the best ways in which to guide operational strategies, business processes and control room tools to support the integration of renewable energy into electrical grids.

  20. Strategies and Decision Support Systems for Integrating Variable Energy Resources in Control Centers for Reliable Grid Operations

    Energy Technology Data Exchange (ETDEWEB)

    Jones, Lawrence E. [Alstom Grid Inc., Washington, DC (United States)


    This report provides findings from the field regarding the best ways in which to guide operational strategies, business processes and control room tools to support the integration of renewable energy into electrical grids.

  1. Artificial intelligent decision support for low-cost launch vehicle integrated mission operations (United States)

    Szatkowski, Gerard P.; Schultz, Roger


    The feasibility, benefits, and risks associated with Artificial Intelligence (AI) Expert Systems applied to low cost space expendable launch vehicle systems are reviewed. This study is in support of the joint USAF/NASA effort to define the next generation of a heavy-lift Advanced Launch System (ALS) which will provide economical and routine access to space. The significant technical goals of the ALS program include: a 10 fold reduction in cost per pound to orbit, launch processing in under 3 weeks, and higher reliability and safety standards than current expendables. Knowledge-based system techniques are being explored for the purpose of automating decision support processes in onboard and ground systems for pre-launch checkout and in-flight operations. Issues such as: satisfying real-time requirements, providing safety validation, hardware and Data Base Management System (DBMS) interfacing, system synergistic effects, human interfaces, and ease of maintainability, have an effect on the viability of expert systems as a useful tool.

  2. Performance of Single Electrode-Supported Cells Operating in the Electrolysis Mode

    Energy Technology Data Exchange (ETDEWEB)

    J. E. O' Brien; G. K. Housley; D. G. Milobar


    An experimental study is under way to assess the performance of electrode-supported solid-oxide cells operating in the steam electrolysis mode for hydrogen production over a temperature range of 800 to 900ºC. Results presented in this paper were obtained from single cells, with an active area of 16 cm2 per cell. The electrolysis cells are electrode-supported, with yttria-stabilized zirconia (YSZ) electrolytes (~10 µm thick), nickel-YSZ steam/hydrogen electrodes (~1400 µm thick), and manganite (LSM) air-side electrodes. The experiments were performed over a range of steam inlet mole fractions (0.1 – 0.6), gas flow rates, and current densities (0 to 0.6 A/cm2). Steam consumption rates associated with electrolysis were measured directly using inlet and outlet dewpoint instrumentation. On a molar basis, the steam consumption rate is equal to the hydrogen production rate. Cell performance was evaluated by performing DC potential sweeps at 800, 850, and 900°C. The voltage-current characteristics are presented, along with values of area-specific resistance as a function of current density. Long-term cell performance is also assessed to evaluate cell degradation. Details of the custom single-cell test apparatus developed for these experiments are also presented.

  3. Care Management In The Family Health Support Core: Technologies Operated In The Professional Dimension

    Directory of Open Access Journals (Sweden)

    José Maria Ximenes Guimarães


    Full Text Available Introduction: The Centre for Health Support Family - NASF has a innovative character with potential to concretize change in the organization of services and in care practices, supporting and expanding the solvability of the actions of the teams of the Family Health Strategy - FHS. To this end, it must operationalize technologies, arrangements and care management devices. Objective: To describe the care management technologies, particularly in the professional dimension, operated by the teams of the Support Centre for Family Health, in its dialogue with the Health Strategy. Methods: case study with a qualitative approach, with the 12 professionals from a NASF team of Maracanaú, Ceará, Brazil. Focal group was performed. The empirical material was analysed based on the content analysis. Results: there is evidence of a proposal for production of integral care based on the use of technologies as host, bond, autonomy and accountability. The user approach is based on the principles of the extended clinic. However, there are difficulties related to the regulation of access, the construction of bonds, the construction of therapeutic projects and intersectional articulation. Final thoughts: it appears necessary to overcome the challenges, strengthen mechanisms for coordination and for negotiation of labour, as well as rethinking the NASF linking logic to a seemingly high number of FHS teams complicates the organization of work processes, building of agendas, weakens the bonds with the users and even the solvency.

  4. Application of biofilm bioreactors in white biotechnology. (United States)

    Muffler, K; Lakatos, M; Schlegel, C; Strieth, D; Kuhne, S; Ulber, R


    The production of valuable compounds in industrial biotechnology is commonly done by cultivation of suspended cells or use of (immobilized) enzymes rather than using microorganisms in an immobilized state. Within the field of wastewater as well as odor treatment the application of immobilized cells is a proven technique. The cells are entrapped in a matrix of extracellular polymeric compounds produced by themselves. The surface-associated agglomerate of encapsulated cells is termed biofilm. In comparison to common immobilization techniques, toxic effects of compounds used for cell entrapment may be neglected. Although the economic impact of biofilm processes used for the production of valuable compounds is negligible, many prospective approaches were examined in the laboratory and on a pilot scale. This review gives an overview of biofilm reactors applied to the production of valuable compounds. Moreover, the characteristics of the utilized materials are discussed with respect to support of surface-attached microbial growth.

  5. Isolation and Purification of Biotechnological Products (United States)

    Hubbuch, Jürgen; Kula, Maria-Regina


    The production of modern pharma proteins is one of the most rapid growing fields in biotechnology. The overall development and production is a complex task ranging from strain development and cultivation to the purification and formulation of the drug. Downstream processing, however, still accounts for the major part of production costs. This is mainly due to the high demands on purity and thus safety of the final product and results in processes with a sequence of typically more than 10 unit operations. Consequently, even if each process step would operate at near optimal yield, a very significant amount of product would be lost. The majority of unit operations applied in downstream processing have a long history in the field of chemical and process engineering; nevertheless, mathematical descriptions of the respective processes and the economical large-scale production of modern pharmaceutical products are hampered by the complexity of the biological feedstock, especially the high molecular weight and limited stability of proteins. In order to develop new operational steps as well as a successful overall process, it is thus a necessary prerequisite to develop a deeper understanding of the thermodynamics and physics behind the applied processes as well as the implications for the product.

  6. Maintaining a Local Data Integration System in Support of Weather Forecast Operations (United States)

    Watson, Leela R.; Blottman, Peter F.; Sharp, David W.; Hoeth, Brian


    Since 2000, both the National Weather Service in Melbourne, FL (NWS MLB) and the Spaceflight Meteorology Group (SMG) have used a local data integration system (LDIS) as part of their forecast and warning operations. Each has benefited from 3-dimensional analyses that are delivered to forecasters every 15 minutes across the peninsula of Florida. The intent is to generate products that enhance short-range weather forecasts issued in support of NWS MLB and SMG operational requirements within East Central Florida. The current LDIS uses the Advanced Regional Prediction System (ARPS) Data Analysis System (ADAS) package as its core, which integrates a wide variety of national, regional, and local observational data sets. It assimilates all available real-time data within its domain and is run at a finer spatial and temporal resolution than current national- or regional-scale analysis packages. As such, it provides local forecasters with a more comprehensive and complete understanding of evolving fine-scale weather features. Recent efforts have been undertaken to update the LDIS through the formal tasking process of NASA's Applied Meteorology Unit. The goals include upgrading LDIS with the latest version of ADAS, incorporating new sources of observational data, and making adjustments to shell scripts written to govern the system. A series of scripts run a complete modeling system consisting of the preprocessing step, the main model integration, and the post-processing step. The preprocessing step prepares the terrain, surface characteristics data sets, and the objective analysis for model initialization. Data ingested through ADAS include (but are not limited to) Level II Weather Surveillance Radar- 1988 Doppler (WSR-88D) data from six Florida radars, Geostationary Operational Environmental Satellites (GOES) visible and infrared satellite imagery, surface and upper air observations throughout Florida from NOAA's Earth System Research Laboratory/Global Systems Division

  7. Enhancing network centric operations doctrine to support civil military cooperation in disaster management

    NARCIS (Netherlands)

    Wolbers, J.J.; Beeres, R.; Bakx, G.; de Waard, E.; Rietjens, S.


    Network Centric Operations is a promising command doctrine in both military operations and during civil disaster management. As both sectors started intensifying their joint operational capacity through civil-military collaboration, it becomes increasingly relevant to address the different command

  8. The development and validation of the biotechnology problem-solving skills assessment for community college biotechnology students (United States)

    Lavoie, Bethann

    As the biotechnology industry grows rapidly, it requires increasing numbers of biotechnicians with problem-solving skills and technical knowledge, yet a college-level, work-related and completely validated assessment measuring biotechnology problem solving skills does not exist in test banks or the problem-based learning literature. The purpose of this study was to develop and validate two parallel forms of an instrument that measures the biotechnology problem-solving skills of students enrolled in community college biotechnology programs. The Biotechnology Problem-Solving Skills Assessment is a 17-item, written, short-answer test containing work-related biotechnology problems in five short problem analysis cases and one integrated performance memo. The assessment validation process answered research questions about the reliability of scores on the assessment, its usefulness and authenticity, and the extent to which scores on the assessment support inferences about students' biotechnology problem-solving skills on the job. The assessment evolved through three testing phases: preliminary, pilot, and field testing. In each round of testing the assessment was administered, and students and experts were interviewed. Additionally during the field test with 115 students and 11 experts, three raters scored 10 student assessments, and two expert biotechnicians rated 10 student assessments. The assessment scores were reliable (alpha = 0.81 for form A and 0.69 for form B). The assessment was viewed as authentic and useful for giving students feedback, as an instructional tool, and as a possible interviewing tool. Student scores on the assessment correlated positively with a proxy measure of on the job problem-solving performance, employer ratings of student assessment answers (rho = 0.746, p = 0.013). Experts validated the biotechnology and problem-solving content on the assessment. Intra- and inter-rater reliabilities were reasonable (intrarater, rho = 0.94, 0.91, and 0

  9. Introduction of the computer-based operation training tools in classrooms to support simulator training

    International Nuclear Information System (INIS)

    Noji, K.; Suzuki, K.; Kobayashi, A.


    Operation training with full-scope simulators is effective to improve trainees operation competency. To obtain more effective results of simulator training, roles of the ''classroom operation training'' closely cooperated to simulator training are important. The ''classroom operation training'' is aimed at pre- and post-studies for operation knowledge related to operation training using full-scope simulators. We have been developing computer-based operation training tools which are used in classroom training sessions. As the first step, we developed the Simulator Training Replay System. This is an aiding tool in the classroom used to enhance trainees operation performance. This system can synchronously replay plant behavior on CRT display with operators action on a video monitor in the simulator training sessions. This system is used to review plant behavior - trainees response after simulator training sessions and to understand plant behavior - operation procedure before operation training. (author)

  10. Biotechnology information service of the GDR

    International Nuclear Information System (INIS)

    Poetzsch, E.


    The paper gives a survey of the biotechnology information in the GDR and describes the establishment of the Biotechnology Information Service of the GDR (BioInfo GDR). BioInfo GDR is a referral database and is to provide information on information sources available in the GDR, and on institutions working in the various fields of biotechnology in the GDR. In addition, some general problems of the building and use of databases are discussed. (author). 8 refs

  11. Cancer Biotechnology | Center for Cancer Research (United States)

    Biotechnology advances continue to underscore the need to educate NCI fellows in new methodologies. The Cancer Biotechnology course will be held on the NCI-Frederick campus on January 29, 2016 (Bldg. 549, Main Auditorium) and the course will be repeated on the Bethesda campus on February 9, 2016 (Natcher Balcony C). The latest advances in DNA, protein and image analysis will be presented. Clinical and postdoctoral fellows who want to learn about new biotechnology advances are encouraged to attend this course.

  12. Editorial: Latest methods and advances in biotechnology. (United States)

    Lee, Sang Yup; Jungbauer, Alois


    The latest "Biotech Methods and Advances" special issue of Biotechnology Journal continues the BTJ tradition of featuring the latest breakthroughs in biotechnology. The special issue is edited by our Editors-in-Chief, Prof. Sang Yup Lee and Prof. Alois Jungbauer and covers a wide array of topics in biotechnology, including the perennial favorite workhorses of the biotech industry, Chinese hamster ovary (CHO) cell and Escherichia coli. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. Biotechnology: Challenge for the food industry


    Popov Stevan


    According to the broadest definition, biotechnology is the use of living matter (plants, animals and microorganisms) in industry, environment protection, medicine and agriculture. Biotechnology takes a key position in the field of food processing during thousands of years. Last about fifty years brought dynamical development of knowledges in the natural sciences especially in domain of genetics and manipulation of genes. Biotechnology for which active role in the on-coming times could be fore...

  14. Past, Present, and Future Industrial Biotechnology in China (United States)

    Li, Zhenjiang; Ji, Xiaojun; Kan, Suli; Qiao, Hongqun; Jiang, Min; Lu, Dingqiang; Wang, Jun; Huang, He; Jia, Honghua; Ouyuang, Pingkai; Ying, Hanjie

    Fossil resources, i.e. concentrated carbon from biomass, have been irrecoverably exhausted through modern industrial civilization in the last two hundred years. Serious consequences including crises in resources, environment and energy, as well as the pressing need for direct and indirect exploitation of solar energy, pose challenges to the science and technology community of today. Bioenergy, bulk chemicals, and biomaterials could be produced from renewable biomass in a biorefinery via biocatalysis. These sustainable industries will match the global mass cycle, creating a new form of civilization with new industries and agriculture driven by solar energy. Industrial biotechnology is the dynamo of a bioeconomy, leading to a new protocol for production of energy, bulk chemicals, and materials. This new mode of innovation will place the industry at center stage supported by universities and research institutes. Creativity in industrial biotechnology will be promoted and China will successfully follow the road to green modernization. China's rapid economic development and its traditional capacity in fermentation will place it in an advantageous position in the industrial biotechnology revolution. The development and current status of industrial biotechnology in China are summarized herein.

  15. Past, present, and future industrial biotechnology in China. (United States)

    Li, Zhenjiang; Ji, Xiaojun; Kan, Suli; Qiao, Hongqun; Jiang, Min; Lu, Dingqiang; Wang, Jun; Huang, He; Jia, Honghua; Ouyuang, Pingkai; Ying, Hanjie


    Fossil resources, i.e. concentrated carbon from biomass, have been irrecoverably exhausted through modern industrial civilization in the last two hundred years. Serious consequences including crises in resources, environment and energy, as well as the pressing need for direct and indirect exploitation of solar energy, pose challenges to the science and technology community of today. Bioenergy, bulk chemicals, and biomaterials could be produced from renewable biomass in a biorefinery via biocatalysis. These sustainable industries will match the global mass cycle, creating a new form of civilization with new industries and agriculture driven by solar energy. Industrial biotechnology is the dynamo of a bioeconomy, leading to a new protocol for production of energy, bulk chemicals, and materials. This new mode of innovation will place the industry at center stage supported by universities and research institutes. Creativity in industrial biotechnology will be promoted and China will successfully follow the road to green modernization. China's rapid economic development and its traditional capacity in fermentation will place it in an advantageous position in the industrial biotechnology revolution. The development and current status of industrial biotechnology in China are summarized herein.

  16. Spectralon BRDF and DHR Measurements in Support of Satellite Instruments Operating Through Shortwave Infrared (United States)

    Georgiev, Georgi T.; Butler, James J.; Thome, Kurt; Cooksey, Catherine; Ding, Leibo


    Satellite instruments operating in the reflective solar wavelength region require accurate and precise determination of the Bidirectional Reflectance Distribution Functions (BRDFs) of the laboratory and flight diffusers used in their pre-flight and on-orbit calibrations. This paper advances that initial work and presents a comparison of spectral Bidirectional Reflectance Distribution Function (BRDF) and Directional Hemispherical Reflectance (DHR) of Spectralon*, a common material for laboratory and onorbit flight diffusers. A new measurement setup for BRDF measurements from 900 nm to 2500 nm located at NASA Goddard Space Flight Center (GSFC) is described. The GSFC setup employs an extended indium gallium arsenide detector, bandpass filters, and a supercontinuum light source. Comparisons of the GSFC BRDF measurements in the ShortWave InfraRed (SWIR) with those made by the NIST Spectral Trifunction Automated Reference Reflectometer (STARR) are presented. The Spectralon sample used in this study was 2 inch diameter, 99% white pressed and sintered Polytetrafluoroethylene (PTFE) target. The NASA/NIST BRDF comparison measurements were made at an incident angle of 0 deg and viewing angle of 45 deg. Additional BRDF data not compared to NIST were measured at additional incident and viewing angle geometries and are not presented here The total combined uncertainty for the measurement of BRDF in the SWIR range made by the GSFC scatterometer is less than 1% (k=1). This study is in support of the calibration of the Joint Polar Satellite System (JPSS) Radiation Budget Instrument (RBI) and Visible Infrared Imaging Radiometer Suite (VIIRS) of and other current and future NASA remote sensing missions operating across the reflected solar wavelength region.

  17. Spring 2008 Industry Study: Biotechnology Industry

    National Research Council Canada - National Science Library

    Anttonen, John; Darnauer, Trish; Douglas, Tim; Ferrari, John; Zimdahl, Jennifer; Hall, Ian M; King, William; Klotzsche, Carl; Miller, Doug; Packard, Doug; Renegar, Mike; Rimback, Ed; Rogers, Gordon; Schnedar, Chris; Sekulovski, Zoran


    Defined broadly as the manipulation of genetic material in living organisms or the derivatives thereof, biotechnology represents a veritable gold mine of possibilities for improving the human condition...

  18. Leningrad NPP full scope simulator upgrade for PPC HMI improvement and operator support systems development and testing

    International Nuclear Information System (INIS)


    The Project Objective was further development of Training Support Center (TSC) created at the Leningrad NPP (LNPP, Sosnovy Bor, Russia) which incorporates full-scope and analytical simulators to provide plant's DCS HMI and OSS improvement. The Project also gave possibilities of development, adjusting and testing of any new or up-graded Operators' Support System before its installation at the reference unit. Upgraded Simulators ensure the modeling of a wide range of accidents and transients and provide with special software and ETHERNET data process communications with the Operator Support Systems prototypes. RRC 'Kurchatov Institute' and LNPP team has implemented the Project jointly

  19. Dredging Operations Technical Support Program. A Framework for Assessing the Need for Seasonal Restrictions on Dredging and Disposal Operations (United States)


    Table 8). Interpretation of this literature, however, is limited by the lack of standardization among experiments and differing experimental protocols...401. Trueman, E. R., and Foster-Smith, R. L. 1976. "The Mechanisms of Burrowing of Sipunculus nudus ," Journal of Zoology, London, Vol 179, pp 373-386...AND DISPOSAL OPERATIONS by Mark W. LaSalle, Douglas G. Clarke __Environmental Laboratory DEPARTMENT OF THE ARMY giWaterways Experiment Station, Corps

  20. UPC Scaling-up methodology for Deterministic Safety Assessment and Support to Plant Operation

    Energy Technology Data Exchange (ETDEWEB)

    Martínez-Quiroga, V.; Reventós, F.; Batet, Il.


    Best Estimate codes along with necessary nodalizations are widely used tools in nuclear engineering for both Deterministic Safety Assessment (DSA) and Support to Plant Operation and Control. In this framework, the application of quality assurance procedures in both codes and nodalizations becomes an essential step prior any significant study. Along these lines the present paper introduces the UPC SCUP, a systematic methodology based on the extrapolation of the Integral Test Facilities (ITF) post-test simulations by means of scaling analyses. In that sense, SCUP fulfills a gap in current nodalization qualification procedures, the related with the validation of NPP nodalizations for Design Basis Accidents conditions. Three are the pillars that support SCUP: judicial selection of the experimental transients, full confidence in the quality of the ITF simulations, and simplicity in justifying discrepancies that appear between ITF and NPP counterpart transients. The techniques that are presented include the socalled Kv scaled calculations as well as the use of two new approaches, ”Hybrid nodalizations” and ”Scaled-up nodalizations”. These last two methods have revealed themselves to be very helpful in producing the required qualification and in promoting further improvements in nodalization. The study of both LSTF and PKL counterpart tests have allowed to qualify the methodology by the comparison with experimental data. Post-test simulations at different sizes allowed to define which phenomena could be well reproduced by system codes and which not, in this way also establishing the basis for the extrapolation to an NPP scaled calculation. Furthermore, the application of the UPC SCUP methodology demonstrated that selected phenomena can be scaled-up and explained between counterpart simulations by carefully considering the differences in scale and design. (Author)

  1. Analysis of operator support method based on intelligent dynamic interlock in lead-cooled fast reactor simulator

    International Nuclear Information System (INIS)

    Xu, Peng; Wang, Jianye; Yang, Minghan; Wang, Weitian; Bai, Yunqing; Song, Yong


    Highlights: • We development an operator support method based on intelligent dynamic interlock. • We offer an integrated aid system to reduce the working strength of operators. • The method can help operators avoid dangerous, irreversible operation. • This method can be used in the fusion research reactor in the further. - Abstract: In nuclear systems, operators have to carry out corrective actions when abnormal situations occur. However, operators might make mistakes under pressure. In order to avoid serious consequences of the human errors, a new method for operators support based on intelligent dynamic interlock was proposed. The new method based on full digital instrumentation and control system, contains real-time alarm analysis process, decision support process and automatic safety interlock process. Once abnormal conditions occur, necessary safety interlock parameter based on analysis of real-time alarm and decision support process can be loaded into human-machine interfaces and controllers automatically, and avoid human errors effectively. Furthermore, the new method can make recommendations for further use and development of this technique in nuclear power plant or fusion research reactor.

  2. Biotechnological uses of archaeal extremozymes. (United States)

    Eichler, J


    Archaea have developed a variety of molecular strategies to survive the often harsh environments in which they exist. Although the rules that allow archaeal enzymes to fulfill their catalytic functions under extremes of salinity, temperature or pressure are not completely understood, the stability of these extremophilic enzymes, or extremozymes, in the face of adverse conditions has led to their use in a variety of biotechnological applications in which such tolerances are advantageous. In the following, examples of commercially important archaeal extremozymes are presented, potentially useful archaeal extremozyme sources are identified and solutions to obstacles currently hindering wider use of archaeal extremozymes are discussed.

  3. Biotechnology, Industry Study, Spring 2009 (United States)

    2009-01-01 12 In 2007, the US share of world production was 42.6% for corn, 32.0% for soybeans , 9.3% for wheat, and 1.5...for rice. Of global exports, the US accounted for 64.5% for corn, 39.4% for soybeans , 32.1% for wheat, and 9.7% for rice. Jim Monke, CRS Report...papers.cfm?abstract_id=1321054 28 Monsanto Company, "Conversations About Plant Biotechnology," April 25, 2009, gmo /asp

  4. Infusing Authentic Inquiry into Biotechnology (United States)

    Hanegan, Nikki L.; Bigler, Amber


    Societal benefit depends on the general public's understandings of biotechnology (Betsch in World J Microbiol Biotechnol 12:439-443, 1996; Dawson and Cowan in Int J Sci Educ 25(1):57-69, 2003; Schiller in Business Review: Federal Reserve Bank of Philadelphia (Fourth Quarter), 2002; Smith and Emmeluth in Am Biol Teach 64(2):93-99, 2002). A National Science Foundation funded survey of high school biology teachers reported that hands-on biotechnology education exists in advanced high school biology in the United States, but is non-existent in mainstream biology coursework (Micklos et al. in Biotechnology labs in American high schools, 1998). The majority of pre-service teacher content preparation courses do not teach students appropriate content knowledge through the process of inquiry. A broad continuum exists when discussing inquiry-oriented student investigations (Hanegan et al. in School Sci Math J 109(2):110-134, 2009). Depending on the amount of structure in teacher lessons, inquiries can often be categorized as guided or open. The lesson can be further categorized as simple or authentic (Chinn and Malhotra in Sci Educ 86(2):175-218, 2002). Although authentic inquiries provide the best opportunities for cognitive development and scientific reasoning, guided and simple inquiries are more often employed in the classroom (Crawford in J Res Sci Teach 37(9):916-937, 2000; NRC in Inquiry and the national science education standards: a guide for teaching and learning, 2000). For the purposes of this study we defined inquiry as "authentic" if original research problems were resolved (Hanegan et al. in School Sci Math J 109(2):110-134, 2009; Chinn and Malhotra in Sci Educ 86(2):175-218, 2002; Roth in Authentic school science: knowing and learning in open-inquiry science laboratories, 1995). The research question to guide this study through naturalistic inquiry research methods was: How will participants express whether or not an authentic inquiry experience enhanced

  5. Biotechnology in petroleum recovery. The microbial EOR

    Energy Technology Data Exchange (ETDEWEB)

    Sen, Ramkrishna [Department of Biotechnology, Indian Institute of Technology (IIT), Kharagpur, West Bengal 721302 (India)


    Biotechnology has played a significant role in enhancing crude oil recovery from the depleted oil reservoirs to solve stagnant petroleum production, after a three-stage recovery process employing mechanical, physical and chemical methods. Biotechnologically enhanced oil recovery processes, known as microbial enhanced oil recovery (MEOR), involve stimulating indigenous reservoir microbes or injecting specially selected consortia of natural bacteria into the reservoir to produce specific metabolic events that lead to improved oil recovery. This also involves flooding with oil recovery agents produced ex situ by industrial or pilot scale fermentation. This paper essentially reviews the operating mechanisms and the progress made in enhanced oil recovery through the use of microbes and their metabolic products. Improvement in oil recovery by injecting solvents and gases or by energizing the reservoir microflora to produce them in situ for carbonate rock dissolution and reservoir re-pressurization has been enunciated. The role of biosurfactants in oil mobilization through emulsification and that of biopolymers for selective plugging of oil-depleted zones and for biofilm formation have been delineated. The spoil sport played by sulfate-reducing bacteria (SRB) in MEOR has also been briefly reviewed. The importance of mathematical models used in predicting the applicability of an MEOR strategy and the microbial growth and transport has been qualitatively discussed. The results of some laboratory studies and worldwide field trials applying ex situ and in situ MEOR technologies were compiled and interpreted. However, the potential of the MEOR technologies has not been fully realized due to poor yield of the useful microbial metabolic products, growth inhibition by accumulated toxic metabolites and longer time of incubation. A complete evaluation and assessment of MEOR from an engineering standpoint based on economics, applicability and performance is required to further

  6. Anaerobic biotechnological approaches for production of liquid energy carriers from biomass

    DEFF Research Database (Denmark)

    Karakashev, Dimitar Borisov; Thomsen, Anne Belinda; Angelidaki, Irini


    In recent years, increasing attention has been paid to the use of renewable biomass for energy production. Anaerobic biotechnological approaches for production of liquid energy carriers (ethanol and a mixture of acetone, butanol and ethanol) from biomass can be employed to decrease environmental...... is determined by substrates and microbial communities available as well as the operating conditions applied. In this review, we evaluate the recent biotechnological approaches employed in ethanol and ABE fermentation. Practical applicability of different technologies is discussed taking into account...

  7. Female Genital Mutilation as a Concern for Special Operations and Tactical Emergency Medical Support Medics. (United States)

    Wittich, Arthur C

    Female genital mutilation (FGM), frequently called female genital cutting or female circumcision, is the intentional disfigurement of the external genitalia in young girls and women for the purpose of reducing libido and ensuring premarital virginity. This traditional, nontherapeutic procedure to suppress libido and prevent sexual intercourse before marriage has been pervasive in Northern Africa, the Middle East, and the Arabian peninsula for over 2,500 years. FGM permanently destroys the genital anatomy while frequently causing multiple and serious complications. The International Federation of Gynecology and Obstetrics proposed a classification system of FGM according to the specific genital anatomy removed and the extensiveness of genital disfigurement. Although it has been ruled illegal in most countries, FGM continues to be performed worldwide. With African, Asian, and Middle Eastern immigration to the United States and Europe, western countries are experiencing FGM in regions where these immigrants have concentrated. As deployments of Special Operations Forces (SOF) increase to regions in which FGM is pervasive, and as African, Asian, and Middle Eastern immigration to the United States increases, SOF and Tactical Emergency Medical Support (TEMS) medics will necessarily be called upon to evaluate and treat complications resulting from FGM. The purpose of this article is to educate SOF/TEMS medical personnel about the history, geographic regions, classification of procedures, complications, and medical treatment of patients with FGM. 2017.

  8. Evaluation of Pushback Decision-Support Tool Concept for Charlotte Douglas International Airport Ramp Operations (United States)

    Hayashi, Miwa; Hoang, Ty; Jung, Yoon C.; Malik, Waqar; Lee, Hanbong; Dulchinos, Victoria L.


    This paper proposes a new departure pushback decision-support tool (DST) for airport ramp-tower controllers. It is based on NASA's Spot and Runway Departure Advisor (SARDA) collaborative decision-making concept, except with the modification that the gate releases now are controlled by tactical pushback (or gate-hold) advisories instead of strategic pre-assignments of target pushback times to individual departure flights. The proposed ramp DST relies on data exchange with the airport traffic control tower (ATCT) to coordinate pushbacks with the ATCT's flow-management intentions under current operational constraints, such as Traffic Management Initiative constraints. Airlines would benefit in reduced taxi delay and fuel burn. The concept was evaluated in a human-in-the-loop simulation experiment with current ramp-tower controllers at the Charlotte Douglas International Airport as participants. The results showed that the tool helped reduce taxi time by one minute per flight and overall departure flight fuel consumption by 10-12% without reducing runway throughput. Expect Departure Clearance Time (EDCT) conformance also was improved when advisories were provided. These benefits were attained without increasing the ramp-tower controllers' workload. Additionally, the advisories reduced the ATCT controllers' workload.

  9. Rational selection of alternative, environmentally compatible surfactants for biotechnological production of pharmaceuticals--a step toward green biotechnology. (United States)

    Straub, Jürg Oliver; Shearer, Russel; Studer, Martin


    The biotechnological production of pharmaceutical active substances needs ancillary substances. Surfactants are used at the end of the cell culture as a protection against potential viral or bacterial contamination and to lyse the producing cells for isolation and purification of the products. To find a replacement for a surfactant that had raised environmental concern, environmentally relevant data for potential alternatives were searched for in the literature. Significant data gaps were filled with additional tests: biodegradability, algal growth inhibition, acute daphnid immobilization and chronic daphnid reproduction toxicity, acute fish toxicity, and activated sludge respiration inhibition. The results were used to model removal in the wastewater treatment plants (WWTPs) serving 3 biotechnological production sites in the Roche Group. Predicted environmental concentrations (PECs) were calculated using realistic amounts of surfactants and site-specific wastewater fluxes, modeled removals for the WWTPs and dilution factors by the respective receiving waters. Predicted no-effect concentrations (PNECs) were derived for WWTPs and for both fresh and marine receiving waters as the treated wastewater of 1 production site is discharged into a coastal water. This resulted in a spreadsheet showing PECs, PNECs, and PEC ÷ PNEC risk characterization ratios for the WWTPs and receiving waters for all investigated surfactants and all 3 sites. This spreadsheet now serves as a selection support for the biotechnological developers. This risk-based prioritization of surfactants is a step toward green biotechnological production. © 2014 SETAC.

  10. Students' Knowledge of, and Attitudes towards Biotechnology Revisited, 1995-2014: Changes in Agriculture Biotechnology but Not in Medical Biotechnology (United States)

    Chen, Shao-Yen; Chu, Yih-Ru; Lin, Chen-Yung; Chiang, Tzen-Yuh


    Modern biotechnology is one of the most important scientific and technological revolutions in the 21st century, with an increasing and measurable impact on society. Development of biotechnology curriculum has become important to high school bioscience classrooms. This study has monitored high school students in Taiwan on their knowledge of and…

  11. Food biotechnology: benefits and concerns. (United States)

    Falk, Michael C; Chassy, Bruce M; Harlander, Susan K; Hoban, Thomas J; McGloughlin, Martina N; Akhlaghi, Amin R


    Recent advances in agricultural biotechnology have highlighted the need for experimental evidence and sound scientific judgment to assess the benefits and risks to society. Nutrition scientists and other animal biologists need a balanced understanding of the issues to participate in this assessment. To date most modifications to crop plants have benefited producers. Crops have been engineered to decrease pesticide and herbicide usage, protect against stressors, enhance yields and extend shelf life. Beyond the environmental benefits of decreased pesticide and herbicide application, consumers stand to benefit by development of food crops with increased nutritional value, medicinal properties, enhanced taste and esthetic appeal. There remains concern that these benefits come with a cost to the environment or increased risk to the consumer. Most U.S. consumers are not aware of the extent that genetically modified foods have entered the marketplace. Consumer awareness of biotechnology seems to have increased over the last decade, yet most consumers remain confused over the science. Concern over the impact on the safety of the food supply remains low in the United States, but is substantially elevated in Europe. Before a genetically engineered crop is introduced into commerce it must pass regulatory scrutiny by as many as four different federal regulatory bodies to ensure a safe food supply and minimize the risk to the environment. Key areas for more research are evaluation of the nutritional benefits of new crops, further investigation of the environmental impact, and development of better techniques to identify and track genetically engineered products.

  12. Biotechnology for Solar System Exploration (United States)

    Steele, A.; Maule, J.; Toporski, J.; Parro-Garcia, V.; Briones, C.; Schweitzer, M.; McKay, D.

    With the advent of a new era of astrobiology missions in the exploration of the solar system and the search for evidence of life elsewhere, we present a new approach to this goal, the integration of biotechnology. We have reviewed the current list of biotechnology techniques, which are applicable to miniaturization, automatization and integration into a combined flight platform. Amongst the techniques reviewed are- The uses of antibodies- Fluorescent detection strategies- Protein and DNA chip technology- Surface plasmon resonance and its relation to other techniques- Micro electronic machining (MEMS where applicable to biologicalsystems)- nanotechnology (e.g. molecular motors)- Lab-on-a-chip technology (including PCR)- Mass spectrometry (i.e. MALDI-TOF)- Fluid handling and extraction technologies- Chemical Force Microscopy (CFM)- Raman Spectroscopy We have begun to integrate this knowledge into a single flight instrument approach for the sole purpose of combining several mutually confirming tests for life, organic and/or microbial contamination, as well as prebiotic and abiotic organic chemicals. We will present several innovative designs for new instrumentation including pro- engineering design drawings of a protein chip reader for space flight and fluid handling strategies. We will also review the use of suitable extraction methodologies for use on different solar system bodies.

  13. Marine Extremophiles: A Source of Hydrolases for Biotechnological Applications


    Dalmaso, Gabriel Zamith Leal; Ferreira, Davis; Vermelho, Alane Beatriz


    The marine environment covers almost three quarters of the planet and is where evolution took its first steps. Extremophile microorganisms are found in several extreme marine environments, such as hydrothermal vents, hot springs, salty lakes and deep-sea floors. The ability of these microorganisms to support extremes of temperature, salinity and pressure demonstrates their great potential for biotechnological processes. Hydrolases including amylases, cellulases, peptidases and lipases from hy...

  14. Undergraduate Biotechnology Students' Views of Science Communication (United States)

    Edmondston, Joanne Elisabeth; Dawson, Vaille; Schibeci, Renato


    Despite rapid growth of the biotechnology industry worldwide, a number of public concerns about the application of biotechnology and its regulation remain. In response to these concerns, greater emphasis has been placed on promoting biotechnologists' public engagement. As tertiary science degree programmes form the foundation of the biotechnology…

  15. South-South Collaboration in Health Biotechnology

    International Development Research Centre (IDRC) Digital Library (Canada)

    To map entrepreneurial collaboration we conducted a brief survey on collaborations of health biotechnology/pharmaceutical firms in developing nations. The survey was sent to firms in five developing countries that have been identified as having relatively strong health biotechnology sectors, Brazil, China, Cuba, India and ...

  16. Biotechnology - The role of perceptions of consumers

    Directory of Open Access Journals (Sweden)

    P. Van Heerden


    Full Text Available The development of Biotechnology is aimed at creating improved products. Without the acceptance of biotechnology enhancements by consumers, the development of new products will be hampered. Consumers in different countries perceive genetic engineering differently. In this article the views of foreign and local consumers are investigated.

  17. Biotechnology issues in four Malaysian mainstream newspapers ...

    African Journals Online (AJOL)

    Biotechnology has been identified as the new engine of growth for the transformation of Malaysia into a developed nation by 2020. The objective of this paper is to analyze the impact of National Policy on biotechnology on media reporting in four Malaysian newspapers. Towards this end, a content analysis of four Malaysian ...

  18. Assessment of technology generating institutions in biotechnology ...

    African Journals Online (AJOL)

    Assessment of technology generating institutions in biotechnology innovation system of South-Eastern Nigeria. ... Results of the study revealed that some of the institutions have been involved in biotechnology research for the past two decades but have only significantly invested on bio-processing (58.8%) and cell and ...

  19. Some limitations of the biotechnological revolution | Onyia ...

    African Journals Online (AJOL)

    The objective of this paper is to challenge and possibly change the notion that biotechnology alone is the magic wand that brings solution to all of agriculture's pitfalls, by clarifying misconceptions concerning these underlying assumptions. The article reviews some of the highlights of modern plant biotechnology and ...

  20. Journal of Tropical Microbiology and Biotechnology

    African Journals Online (AJOL)

    The Journal of Tropical Microbiology and Biotechnology (JTMB) formerly Journal of Tropical Microbiology gives preeminence to the central role of modern biotechnology and microorganisms as tools and targets in current research, which is largely multidisciplinary. JTMB covers a broad range of topics, such as disease ...

  1. Assessment of technology generating institutions in biotechnology ...

    African Journals Online (AJOL)



    May 18, 2009 ... farmers on the potentials of biotechnology for food security is expedient. Key words: Biotechnology, innovation system, ... security, increases in agricultural productivity is required. Furthermore, Bunders et al. (1996) had earlier ..... This may be as a result of “publish or perish” syndrome in the universities.

  2. Biotechnology and species development in aquaculture | Ayoola ...

    African Journals Online (AJOL)

    The use of biotechnology in various aspects of human endeavour have obviously created a great impact but not without some risks. Not withstanding, there is still the need for its adoption as more of the already adopted biotechnologies are being improved upon with lesser demerits. Aquaculture is not also left out in the ...

  3. Biotechnology in plant nutrient management for agricultural ...

    African Journals Online (AJOL)

    The potential benefits of biotechnology are extraordinary and traverse sectors like agriculture, environment, health, industry, bio-informatics, and human resource development. In agriculture, biotechnology research has helped to improve the understanding of diseases, to improve the diagnosis and treatment of diseases, ...

  4. Agricultural biotechnology research and development in Ethiopia ...

    African Journals Online (AJOL)

    Ethiopia is an agrarian country that can have enormous benefit from the applications of biotechnology for increasing its agricultural productivity. The country is at initial stages of research and development in agricultural biotechnology with scattered efforts underway in various public institutions. Research efforts and ...

  5. Comparative genomics of biotechnologically important yeasts

    NARCIS (Netherlands)

    Riley, Robert; Haridas, Sajeet; Wolfe, Kenneth H; Lopes, Mariana R; Hittinger, Chris Todd; Göker, Markus; Salamov, Asaf A; Wisecaver, Jennifer H; Long, Tanya M; Calvey, Christopher H; Aerts, Andrea L; Barry, Kerrie W; Choi, Cindy; Clum, Alicia; Coughlan, Aisling Y; Deshpande, Shweta; Douglass, Alexander P; Hanson, Sara J; Klenk, Hans-Peter; LaButti, Kurt M; Lapidus, Alla; Lindquist, Erika A; Lipzen, Anna M; Meier-Kolthoff, Jan P; Ohm, Robin A; Otillar, Robert P; Pangilinan, Jasmyn L; Peng, Yi; Rokas, Antonis; Rosa, Carlos A; Scheuner, Carmen; Sibirny, Andriy A; Slot, Jason C; Stielow, J Benjamin; Sun, Hui; Kurtzman, Cletus P; Blackwell, Meredith; Grigoriev, Igor V; Jeffries, Thomas W


    Ascomycete yeasts are metabolically diverse, with great potential for biotechnology. Here, we report the comparative genome analysis of 29 taxonomically and biotechnologically important yeasts, including 16 newly sequenced. We identify a genetic code change, CUG-Ala, in Pachysolen tannophilus in the

  6. Biotechnology in Aquaculture: Prospects and Challenges | Edun ...

    African Journals Online (AJOL)

    Increased public demands for fish and dwindling natural marine habitats have encouraged scientists to study ways that biotechnology can increase the production of fish and shellfish. Biotechnology allows scientists to identify and combine traits in fish and shellfish to increase productivity and improve quality. This article ...

  7. Biotechnology Education and the Internet. ERIC Digest. (United States)

    Lee, Thomas

    The world of modern biotechnology is based on recent developments in molecular biology, especially those in genetic engineering. Since this is a relatively new and rapidly advancing field of study, there are few traditional sources of information and activities. This digest highlights biotechnology resources including those that can be found on…

  8. The current biotechnology outlook in Malaysia

    Directory of Open Access Journals (Sweden)

    Khairiah Salwa MOKHTAR


    Full Text Available Blessed with extremely rich biodiversity, Malaysia is all geared up to explore new high technology to utilize the advantage it possesses whilst to protect its environment. Biotechnology has been identified as an appropriate driver that can deliver economic gains through research and development, improvement of food security, creation of entrepreneurial opportunities for industrial growth, health and environmental sustainability. This paper attempts to address the evolution of biotechnology institutions and the stumbling blocks in developing the Malaysian biotechnology industry. This paper identifies three main impediments in the current Malaysian biotechnology, namely lack of skilled human capital; weak industrial base; and lack of commercialization effort. Besides, a set of strategies are discussed with aim to further improve and strengthen the Malaysian biotechnology industry. In general, the arguments are presented by mapping out the symbiotic relationship between data from elite interviews, archival data and observations.

  9. Termites as targets and models for biotechnology. (United States)

    Scharf, Michael E


    Termites have many unique evolutionary adaptations associated with their eusocial lifestyles. Recent omics research has created a wealth of new information in numerous areas of termite biology (e.g., caste polyphenism, lignocellulose digestion, and microbial symbiosis) with wide-ranging applications in diverse biotechnological niches. Termite biotechnology falls into two categories: (a) termite-targeted biotechnology for pest management purposes, and (b) termite-modeled biotechnology for use in various industrial applications. The first category includes several candidate termiticidal modes of action such as RNA interference, digestive inhibition, pathogen enhancement, antimicrobials, endocrine disruption, and primer pheromone mimicry. In the second category, termite digestomes are deep resources for host and symbiont lignocellulases and other enzymes with applications in a variety of biomass, industrial, and processing applications. Moving forward, one of the most important approaches for accelerating advances in both termite-targeted and termite-modeled biotechnology will be to consider host and symbiont together as a single functional unit.

  10. Supporting the Co-operative Organisation of Rational Energy Use (SCORE). Bulgaria Country Document

    International Nuclear Information System (INIS)


    SCORE stands for Supporting the Co-operative Organisation of Rational Energy Use. It aims at assisting the social transformation in the Central and Eastern European countries by creating self-supporting structures that are able to stimulate the efficient use of energy in end-user sectors. This document aims at presenting an in-depth institutional analysis of the energy efficiency situation in Bulgaria, including the current situation with regard to energy supply, consumption and environmental aspects, as well as an analysis of energy efficiency policies, instruments and organisations. Also, the document identifies problems related to energy efficiency in Bulgaria and indicates the areas of actions for an integrated SCORE programme in Bulgaria. The input for this process was provided by a survey among the main actors in the field, consisting of a questionnaire and interviews and a review of available information. The results were discussed in a workshop attended by the main stakeholders. The main characteristics of the Bulgarian energy sector are summarised in chapter 2. They indicate a high dependency on imported resources, a low quality of domestic fuels, a relatively high energy intensity of production and a low efficiency at supply and demand side with consider able potential for improvement. The restructuring of the sector has started but the process is far from completed. In the main towns heat is mainly supplied by district heating generated partly in co-generation plants. Gas distribution for public and residential buildings is quickly developing. In Chapter 3 the existing policies and actors are described and a 'roadmap' for energy efficiency actors is given. This provides the basis for defining the priorities for energy efficiency improvements presented in Chapter 4, by analysing the tools, policy instruments and organisations. Barriers and priority actions were defined in relation to the national policy level, the institutional structure, financial and

  11. Combination of artificial intelligence and procedural language programs in a computer application system supporting nuclear reactor operations

    International Nuclear Information System (INIS)

    Town, G.G.; Stratton, R.C.


    A computer application system is described which provides nuclear reactor power plant operators with an improved decision support system. This system combines traditional computer applications such as graphics display with artificial intelligence methodologies such as reasoning and diagnosis so as to improve plant operability. This paper discusses the issues, and a solution, involved with the system integration of applications developed using traditional and artificial intelligence languages

  12. Operating the Cross Spectral Metric Algorithm with Limited Secondary Data Support

    National Research Council Canada - National Science Library

    Hale, Todd


    ...) techniques is secondary data support for the covariance matrix estimate. Reed has shown the required secondary data support to achieve performance within 3 db of optimal SINR is approximately twice the Degrees Of Freedom (DOF) used...

  13. Towards a Risk-based Decision Support for Offshore Wind Turbine Installation and Operation & Maintenance

    DEFF Research Database (Denmark)

    Gintautas, Tomas; Sørensen, John Dalsgaard; Vatne, Sigrid Ringdalen


    Costs of operation & maintenance, assembly, transport and installation of offshore wind turbines contribute significantly to the total cost of offshore wind farm. These operations are mostly carried out by specific ships that have to be hired for the operational phase and for duration of installa......Costs of operation & maintenance, assembly, transport and installation of offshore wind turbines contribute significantly to the total cost of offshore wind farm. These operations are mostly carried out by specific ships that have to be hired for the operational phase and for duration...... weather window predictions, potentially reducing cost of offshore wind energy. This paper presents a novel approach to weather window estimation using ensemble weather forecasts and statistical analysis of simulated installation equipment response....

  14. New technologies in agricultural biotechnology

    Directory of Open Access Journals (Sweden)

    Andras Szekacs


    Full Text Available Technologies that emerged during the last decade as new tools occasionally represent fundamentally new means of genome modification, which, in addition to the scientific novelty, faces legislators with new challenge by giving a new meaning to both the biochemical/molecular biological and legal meaning to genetically modified organisms (GMOs. Emerging plant genetic technologies are categorized as zinc finger nuclease (ZFN technology; oligonucleotide directed mutagenesis; cisgenesis and intragenesis; RNA-dependent DNA methylation by RNA interference; grafting on GM rootstock; reverse breeding; agro-infiltration; and synthetic genomics. Although all these methods apply biotechnology processes to create new plant varieties, it debated whether all result in GMOs according to the current legal definition. Official risk assessment of these technologies is a task of outstanding weight of the authority.

  15. Flashing light in microalgae biotechnology. (United States)

    Abu-Ghosh, Said; Fixler, Dror; Dubinsky, Zvy; Iluz, David


    Flashing light can enhance photosynthesis and improve the quality and quantity of microalgal biomass, as it can increase the products of interest by magnitudes. Therefore, the integration of flashing light effect into microalgal cultivation systems should be considered. However, microalgae require a balanced mix of the light/dark cycle for higher growth rates, and respond to light intensity differently according to the pigments acquired or lost during the growth. This review highlights recently published results on flashing light effect on microalgae and its applications in biotechnology, as well as the recently developed bioreactors designed to fulfill this effect. It also discusses how this knowledge can be applied in selecting the optimal light frequencies and intensities with specific technical properties for increasing biomass production and/or the yield of the chemicals of interest by microalgae belonging to different genera. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. DNA polymerases and biotechnological applications. (United States)

    Aschenbrenner, Joos; Marx, Andreas


    A multitude of biotechnological techniques used in basic research as well as in clinical diagnostics on an everyday basis depend on DNA polymerases and their intrinsic capability to replicate DNA strands with astoundingly high fidelity. Applications with fundamental importance to modern molecular biology, including the polymerase chain reaction and DNA sequencing, would not be feasible without the advances made in characterizing these enzymes over the course of the last 60 years. Nonetheless, the still growing application scope of DNA polymerases necessitates the identification of novel enzymes with tailor-made properties. In the recent past, DNA polymerases optimized for diverse PCR and sequencing applications as well as enzymes that accept a variety of unnatural substrates for the synthesis and reverse transcription of modified nucleic acids have been developed. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Biotechnology and bioforensics new trends

    CERN Document Server

    Kumar, Amit


    This Brief covers broad areas of Applied Biology specifically into the domains of Biotechnology/Biomedicine and Forensic Science. Chapters included here would also explain the role of bioinformatics in protein and gene characterization, modeling of the protein structure, survey related to the chromosomal effect on Human Disorders like Diabetes and Cardiac Problems. This Brief is full of Innovative Literature like Use of Microbes in Electricity Production, Brain connection to Type 2 Diabetes etc. Interesting issues in Forensic biology and the aspects of Bioforensics like STR profiling of exhumed bones makes this brief truly useful and informative for Researchers. It also includes the advancements and new ideologies in understanding crop improvements & crop quality. This Brief witnesses Innovative Research related to the Bio and Agri software development too which are capable of accelerating Insilico biological data analysis.

  18. Training for Success: Intelligence Training in Support of Humanitarian Assistance Operations (United States)


    not have accomplished this thesis or even advanced far enough in my career to be afforded the opportunity to attend the esteemed Army Command FHA operations by participation in Operation United Assistance. Scope and Delimitations The scope and delimitations are self -imposed boundaries...challenge identified was the need to conduct training exercises to develop relationships and refine processes prior to an actual FHA operation (Keen 2010

  19. Drugs obtained by biotechnology processing

    Directory of Open Access Journals (Sweden)

    Hugo Almeida


    Full Text Available In recent years, the number of drugs of biotechnological origin available for many different diseases has increased exponentially, including different types of cancer, diabetes mellitus, infectious diseases (e.g. AIDS Virus / HIV as well as cardiovascular, neurological, respiratory, and autoimmune diseases, among others. The pharmaceutical industry has used different technologies to obtain new and promising active ingredients, as exemplified by the fermentation technique, recombinant DNA technique and the hybridoma technique. The expiry of the patents of the first drugs of biotechnological origin and the consequent emergence of biosimilar products, have posed various questions to health authorities worldwide regarding the definition, framework, and requirements for authorization to market such products.Nos últimos anos, tem aumentado exponencialmente o número de fármacos de origem biotecnológica ao dispor das mais diversas patologias, entre elas destacam-se, os diferentes tipos de cancêr, as doenças infecciosas (ex. vírus AIDS/HIV, as doenças autoimunes, as doenças cardiovasculares, a Diabetes Mellitus, as doenças neurológicas, as doenças respiratórias, entre outras. A indústria farmacêutica tem recorrido a diferentes tecnologias para a obtenção de novos e promissores princípios ativos, como são exemplo a fermentação, a técnica de DNA Recombinante, a técnica de hidridoma, entre outras. A queda das patentes dos primeiros fármacos de origem biotecnológica e o consequente aparecimento dos produtos biossimilares têm colocado diferentes questões às autoridades de saúde mundiais, sobre a definição, enquadramento e exigências para a autorização de entrada no mercado deste tipo de produtos.

  20. Optimization of Combat Logistics Force Required to Support Major Combat Operations

    National Research Council Canada - National Science Library

    Morse, Troy C


    Military requirements development involves operational commanders conducting analyses of a variety of combat scenarios to assess force structure and material requirements to meet their military objectives...

  1. Blending the Battlefield: An Analysis of Using Private Military Companies To Support Military Operations In Iraq

    National Research Council Canada - National Science Library

    Gallup, Heather L


    .... Key factors contributing to the growth include declines in military budgets, reductions in active duty end-strength, increases in operational deployments, advancements in weapon system technology...

  2. Expert system. Based advisory system for the operator's mental activities support

    International Nuclear Information System (INIS)

    Gieci, A.; Macko, J.; Mosny, J.


    The operator's mental activity is the most important part of his work. A processing of a large amount of the information by the operator is possible only if he/she possesses appropriate cognitive skills. To facilitate the novice's acquisition of the experienced operator's cognitive skills of the decision-making process a special type of the expert system was developed. The cognitive engineering's models and problem-solving methodology constitutes the basis of this expert system. The article gives an account of the prototype of the mentioned expert system developed to aid the whole mental activity of the nuclear power plant operator during his decision-making process. (author)

  3. Final Report: Northern Virginia Community College Training for Biotechnology Workers

    Energy Technology Data Exchange (ETDEWEB)

    Weiss, Johanna V


    The intent of this project was to expand Northern Virginia Community College's capability to offer training to support the Biotechnology Industry in the northern Virginia region. The general goal of this project was to create a College Biotechnology Program; specific goals of the project were to a) design curricula/courses to prepare students to become entry-level lab technicians, b) redesign and equip lab space to better suit the needs of the program, c) develop partnerships with the local industry through outreach and the formation on an advisory board, d) recruit students into the program, and e) provide instructional support for local high school teachers. At the end of the grant period, NOVA has successfully created two new curricula in biotechnology: an Associate of Applied Science (A.A.S.) in Biotechnology (initiated in Fall 2008) and a Career Studies Certificate for Biotechnology Lab Technicians (to be initiated in Fall 2010). These curricula were designed with advice from an external advisory committee which is comprised of representatives from industry, transfer institutions and high school administrators. To date, almost all courses have been designed and piloted; the equipment needed for the courses and the initial supplies were paid for by the grant as was the re-modeling of some lab space to be used for the biotech courses. In order to market the program, the NOVA Biotech Program has also established relationships with the local high schools. Presentations were given at several local high schools and on-site workshops were held for high school students and teachers. As a result, close to 1000 students have attended program open houses, presentations within the high schools, or workshops held in the summer. Over 100 teachers have received information and/or training in biotechnology. These outreach efforts as well as high quality curricula have started to attract a number of students to the program – for example, there are currently 70 students

  4. Operational multi-sensor design for forest carbon monitoring to support REDD+ in Kalimantan, Indonesia (United States)

    Braswell, B. H.; Hagen, S. C.; Harris, N.; Saatchi, S. S.


    Parties to the United Nations Framework Convention on Climate Change (UNFCCC) have been requested to establish robust and transparent national forest monitoring systems (NFMS) that use a combination of remote sensing and ground-based forest carbon inventory approaches to estimate anthropogenic forest-related greenhouse gas emissions and removals, reducing uncertainties as far as possible. A country's NFMS should also be used for data collection to inform the assessment of national or subnational forest reference emission levels and/or forest reference levels (RELs/RLs). In this way, the NFMS forms the link between historical assessments and current/future assessments, enabling consistency in the data and information to support the implementation of REDD+ activities in countries. The creation of a reliable, transparent, and comprehensive NFMS is currently limited by a dearth of relevant data that are accurate, low-cost, and spatially resolved at subnational scales. We are developing, evaluating, and validating several critical components of an NFMS in Kalimantan, Indonesia, focusing on the use of LiDAR and radar imagery for improved carbon stock and forest degradation information. Our goal is to evaluate sensor and platform tradeoffs systematically against in situ investments, as well as provide detailed tracking and characterization of uncertainty in a cost-benefit framework. Kalimantan is an ideal area to evaluate the use of remote sensing methods because measuring forest carbon stocks and their human caused changes with a high degree of certainty in areas of dense tropical forests has proven to be difficult. While the proposed NFMS components are being developed at the subnational scale for Kalimantan, we are targeting these methods for applicability across broader geographies and for implementation at various scales. Our intention is for this research to advance the state of the art of Measuring, Reporting, and Verification (MRV) system methodologies in ways

  5. Synthetic biology: regulating industry uses of new biotechnologies. (United States)

    Erickson, Brent; Singh, Rina; Winters, Paul


    In our view, synthetic biology is an extension of the continuum of genetic science that has been used safely for more than 40 years by the biotechnology industry in the development of commercial products. Examples of synthetic biology use by biotechnology companies illustrate the potential to substantially reduce research and development time and to increase speed to market. Improvements in the speed and cost of DNA synthesis are enabling scientists to design modified bacterial chromosomes that can be used in the production of renewable chemicals, biofuels, bioproducts, renewable specialty chemicals, pharmaceutical intermediates, fine chemicals, food ingredients, and health care products. Regulatory options should support innovation and commercial development of new products while protecting the public from potential harms.

  6. The Use of Special Operations Forces in Support of American Strategic Security Strategies (United States)


    efforts. Throughout the final decades of the 20th century, Colombia was a hotbed for drugs and violence punctuated by the operations of Pablo Emilio... Escobar , the drug lord in charge of the infamous Medellín Cartel. Following limited success in counter-narcotic operations during the early 1990s

  7. Army Support of Military Cyberspace Operations: Joint Contexts and Global Escalation Implications (United States)


    Alexander as well as its cur- rent operations led by Admiral Michael Rog - ers. Also, it assesses the command’s mission to direct operations, defend...Questions for Vice Admiral Michael S. Rog - ers, USN Nominee for Commander, United States Cyber Com- mand,” Washington, DC: U.S. Senate, March 11


    NARCIS (Netherlands)



    The concept of the kernel, i.e. the time critical part of a real-time operating system, and its dedicated co-processor, especially tailored for embedded applications, are presented. The co-processor acts as a system controller and operates in conjunction with one or more conventional processors in

  9. Monitoring and operational support on nuclear power plants using an artificial intelligence system

    Energy Technology Data Exchange (ETDEWEB)

    Bianchi, Paulo H.; Baptista Filho, Benedito D., E-mail:, E-mail: bdbfilho@ipen.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)


    The monitoring task in nuclear power plants is of crucial importance with respect to safety and efficient operation. The operators have a wide range of variables to observe and analyze; the quantity of variables and their behavior determine the time they have to take correct decisions. The complexity of such aspects in a nuclear power plant influences both, the plant operational efficiency and the general safety issues. This paper describes an experimental system developed by the authors which aims to assist the operators of nuclear power plants to take quick and safe decisions. The system maps the status of plant and helps the operators to make quick judgments by using artificial intelligence methods. The method makes use of a small set of monitored variables and presents a map of the plant status in a friendly manner. This system uses an architecture that has multiple self-organizing maps to perform these tasks. (author)

  10. Monitoring and operational support on nuclear power plants using an artificial intelligence system

    International Nuclear Information System (INIS)

    Bianchi, Paulo H.; Baptista Filho, Benedito D.


    The monitoring task in nuclear power plants is of crucial importance with respect to safety and efficient operation. The operators have a wide range of variables to observe and analyze; the quantity of variables and their behavior determine the time they have to take correct decisions. The complexity of such aspects in a nuclear power plant influences both, the plant operational efficiency and the general safety issues. This paper describes an experimental system developed by the authors which aims to assist the operators of nuclear power plants to take quick and safe decisions. The system maps the status of plant and helps the operators to make quick judgments by using artificial intelligence methods. The method makes use of a small set of monitored variables and presents a map of the plant status in a friendly manner. This system uses an architecture that has multiple self-organizing maps to perform these tasks. (author)

  11. Real Option in Biotechnological Firms Valuation. An Empirical Analysis of European Firms.

    Directory of Open Access Journals (Sweden)

    Gracia Rubio Martín


    Full Text Available Firms’ intangible assets are becoming more and more relevant in the different areas within the financial discipline. Its management, its quantification and its valuation nowadays constitute one of the main challenges which economy and business try to face. Through this paper we will evaluate some models based on the real options theory in order to estimate the intangible assets value of certain firms, specifically I+D biotechnological firms projects. With this aim, and after deep research on biotechnological industry, we will establish the parameters regarding one model which can be considered as a quantitative valuation method that we apply to a sample of biotechnological European companies. The results obtained through the empirical analysis are promising and they support the use of the real options theory to evaluate biotechnological firms.

  12. Worldwide C-17 Availability to Support 82nd Airborne Operations from Fort Bragg/Pope Field (United States)


    and LTC Jason W. Condrey of Army Forces Command for their support and input throughout the project. We must also thank Army Forces Command for its...Improvement Program kt knots LIMS -EV Logistics, Installations, Mission Support-Enterprise View nm nautical miles PMC partially mission capable USAF...Mission Support-Enterprise View ( LIMS -EV) that give the location and status of the C-17 fleet. Chapter 4 analyzes the model output focused on a heatmap of

  13. Six years of operating experience of the United States' deep geologic disposal site with long-term community support

    International Nuclear Information System (INIS)

    Piper, L.


    This document presents in a series of transparencies the history of the Waste Isolation Pilot Plant (WIPP) facility of the US-DOE, the WIPP repository characteristics, regulatory framework, transportation system and approved shipping routes, the WIPP disposal operations since March 1999, the communities involved, the safety aspects, the community support and positive impact. (J.S.)

  14. Frontiers in biomedical engineering and biotechnology. (United States)

    Liu, Feng; Goodarzi, Ali; Wang, Haifeng; Stasiak, Joanna; Sun, Jianbo; Zhou, Yu


    The 2nd International Conference on Biomedical Engineering and Biotechnology (iCBEB 2013), held in Wuhan on 11–13 October 2013, is an annual conference that aims at providing an opportunity for international and national researchers and practitioners to present the most recent advances and future challenges in the fields of Biomedical Information, Biomedical Engineering and Biotechnology. The papers published by this issue are selected from this conference, which witnesses the frontier in the field of Biomedical Engineering and Biotechnology, which particularly has helped improving the level of clinical diagnosis in medical work.

  15. Supporting the Secure Halting of User Sessions and Processes in the Linux Operating System

    National Research Council Canada - National Science Library

    Brock, Jerome


    .... Only when a session must be reactivated are its processes returned to a runnable state. This thesis presents an approach for adding this "secure halting" functionality to the Linux operating system...

  16. Zouerate 1978: Supporting Air Operations, an Army Team Amidst France's African Strategy

    National Research Council Canada - National Science Library

    Voute, Philippe


    .... To help this country, in 1977-1978, France carried out operation Lamantin. It consisted of surveillance and attack aircraft stationed in Senegal, and small Army teams deployed in Mauritanian garrisons...

  17. Coming in From the Cold ... War: Defense Humint Services Support to Military Operations Other Than War

    National Research Council Canada - National Science Library

    Becker, David


    ...) and theater commander in chiefs (CINCs) in military operations other than war (MOOTW). The examination included a study into the recent history of military HUMINT, and the Department of Defense's (DoD's...

  18. Locating Portable Stations to Support the Operation of Bike Sharing Systems (United States)


    Redistributing bikes has been a major challenge for the daily operation of bike sharing system around the world. Existing literature explore solution strategies that rely on pick-up-and-delivery routing as well as user incentivization approaches. The...

  19. Analysis of rock mass dynamic impact influence on the operation of a powered roof support control system (United States)

    Szurgacz, Dawid; Brodny, Jaroław


    A powered roof support is a machine responsible for protection of an underground excavation against deformation generated by rock mass. In the case of dynamic impact of rock mass, the proper level of protection is hard to achieve. Therefore, the units of the roof support and its components are subject to detailed tests aimed at acquiring greater reliability, efficiency and efficacy. In the course of such test, however, it is not always possible to foresee values of load that may occur in actual conditions. The article presents a case of a dynamic load impacting the powered roof support during a high-energy tremor in an underground hard coal mine. The authors discuss the method for selecting powered roof support units proper for specific forecasted load conditions. The method takes into account the construction of the support and mining and geological conditions of an excavation. Moreover, the paper includes tests carried out on hydraulic legs and yield valves which were responsible for additional yielding of the support. Real loads impacting the support unit during tremors are analysed. The results indicated that the real registered values of the load were significantly greater than the forecasted values. The analysis results of roof support operation during dynamic impact generated by the rock mass (real life conditions) prompted the authors to develop a set of recommendations for manufacturers and users of powered roof supports. These include, inter alia, the need for innovative solutions for testing hydraulic section systems.

  20. Conduct and Support of Amphibious Operations from United States Submarines in World War II (United States)


    operate at fleet speeds in advance of a battle fleet, the Navy‘s General Board determined that endurance and habitability were more important for long...Pacific operations addressed in this monograph. Source: Modified from West Point Atlas. atlases /ww2%20pacific...Task Force. Source: Modified from West Point Atlas. atlases /ww2%20europe/EuropeanTheaterGIF/WWIIEuro

  1. Operator support systems in NPPs. Summary of the activities in the period 1993-1995

    International Nuclear Information System (INIS)

    Silvani, V.


    The report presents an overview of major activities performed in ENEA and ANPA in the period 1993-1995 related to CRP subject. Being in Italy the Nuclear Power Plant not in operation since 1987, studied and research under development related to the CRP subject make reference to technological themes such as the methods to improve the software quality in critical application and the methods to improve the operator training. (author). 5 refs

  2. Simple Automatic File Exchange (SAFE) to Support Low-Cost Spacecraft Operation via the Internet (United States)

    Baker, Paul; Repaci, Max; Sames, David


    Various issues associated with Simple Automatic File Exchange (SAFE) are presented in viewgraph form. Specific topics include: 1) Packet telemetry, Internet IP networks and cost reduction; 2) Basic functions and technical features of SAFE; 3) Project goals, including low-cost satellite transmission to data centers to be distributed via an Internet; 4) Operations with a replicated file protocol; 5) File exchange operation; 6) Ground stations as gateways; 7) Lessons learned from demonstrations and tests with SAFE; and 8) Feedback and future initiatives.

  3. Designer cell signal processing circuits for biotechnology. (United States)

    Bradley, Robert W; Wang, Baojun


    Microorganisms are able to respond effectively to diverse signals from their environment and internal metabolism owing to their inherent sophisticated information processing capacity. A central aim of synthetic biology is to control and reprogramme the signal processing pathways within living cells so as to realise repurposed, beneficial applications ranging from disease diagnosis and environmental sensing to chemical bioproduction. To date most examples of synthetic biological signal processing have been built based on digital information flow, though analogue computing is being developed to cope with more complex operations and larger sets of variables. Great progress has been made in expanding the categories of characterised biological components that can be used for cellular signal manipulation, thereby allowing synthetic biologists to more rationally programme increasingly complex behaviours into living cells. Here we present a current overview of the components and strategies that exist for designer cell signal processing and decision making, discuss how these have been implemented in prototype systems for therapeutic, environmental, and industrial biotechnological applications, and examine emerging challenges in this promising field. Copyright © 2015 The Authors. Published by Elsevier B.V. All rights reserved.

  4. A Path to Operating System and Runtime Support for Extreme Scale Tools

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Barton P; Roth, Philip; DelSignore, John


    In this project, we cast distributed resource access as operations on files in a global name space and developed a common, scalable solution for group operations on distributed processes and files. The resulting solution enables tool and middleware developers to quickly create new scalable software or easily improve the scalability of existing software. The cornerstone of the project was the design of a new programming idiom called group file operations that eliminates iterative behavior when a single process must apply the same set of file operations to a group of related files. To demonstrate our novel and scalable ideas for group file operations and global name space composition, we developed a group file system called TBON-FS that leverages a tree-based overlay network (TBON), specifically MRNet, for logarithmic communication and distributed data aggregation. We also developed proc++, a new synthetic file system co-designed for use in scalable group file operations. Over the course of the project, we evaluated the utility and performance of group file operations, global name space composition, TBON-FS, and proc++ in three case studies. The first study focused on the ease in using group file operations and TBON-FS to quickly develop several new scalable tools for distributed system administration and monitoring. The second study evaluated the integration of group file operation and TBON-FS within the Ganglia Distributed Monitoring System to improve its scalability for clusters. The final study involved the integration of group file operations, TBON-FS, and proc++ within TotalView, the widely-used parallel debugger. For this project, the work of the Oak Ridge National Laboratory (ORNL) team occurred primarily in two directions: bringing the MRNet tree-based overlay network (TBON) implementation to the Cray XT platform, and investigating techniques for predicting the performance of MRNet topologies on such systems. Rogue Wave Software (RWS), formerly Total

  5. Nuclear piping and pipe support design and operability relating to loadings and small bore piping

    International Nuclear Information System (INIS)

    Stout, D.H.; Tubbs, J.M.; Callaway, W.O.; Tang, H.T.; Van Duyne, D.A.


    The present nuclear piping system design practices for loadings, multiple support design and small bore piping evaluation are overly conservative. The paper discusses the results developed for realistic definitions of loadings and loading combinations with methodology for combining loads under various conditions for supports and multiple support design. The paper also discusses a simplified method developed for performing deadweight and thermal evaluations of small bore piping systems. Although the simplified method is oriented towards the qualification of piping in older plants, this approach is applicable to plants designed to any edition of the ASME Section III or B31.1 piping codes

  6. Applying Multi-Class Support Vector Machines for performance assessment of shipping operations: The case of tanker vessels

    DEFF Research Database (Denmark)

    Pagoropoulos, Aris; Møller, Anders H.; McAloone, Tim C.


    of feature selection algorithms. Afterwards, a model based on Multi- Class Support Vector Machines (SVM) was constructed and the efficacy of the approach is shown through the application of a test set. The results demonstrate the importance and benefits of machine learning algorithms in driving energy......Energy efficient operations are a key competitive advantage for modern shipping companies. During the operation of the vessel, improvements in energy use can be achieved by not only by technical upgrades, but also through behavioural changes in the way the crew on board is operating the vessels....... Identifying the potential of behavioural savings can be challenging, due to the inherent difficulty in analysing the data and operationalizing energy efficiency within the dynamic operating environment of the vessels. This article proposes a supervised learning model for identifying the presence of energy...

  7. Real Vegan Cheese and the Artistic Critique of Biotechnology

    Directory of Open Access Journals (Sweden)

    Rebecca Wilbanks


    Full Text Available Drawing on the case study of Real Vegan Cheese (RVC, a synthetic biology project housed in a community lab or “biohackerspace,” I argue that biohacking performs an “artistic critique” of the bioeconomy. Following Boltanski and Chiapello’s use of the term, the “artistic critique” pits values of autonomy and creativity against a view of capitalist production as standardized and alienating, represented (in the case of biotechnology by Monsanto’s monoculture GMOs. In this way, biohacking is depicted as liberating biotechnology from the constraints of corporate and academic institutions. Through the use of design fiction and a playful aesthetic, projects such as RVC demonstrate a more legitimate––with respect to the values of the artistic critique––mode of production for a new generation of biotechnology products, one that is portrayed as driven primarily by ethical and aesthetic values rather than the profit motive. This analysis highlights the role that aesthetic and affective strategies play in advancing particular sociotechnical visions, and the way that biohacking projects operate in symbiosis with incumbent institutions even as they define themselves in opposition to them. Finally, it suggests that biohacking has certain limitations when considered as a form of public engagement with science.

  8. [The past 30 years of Chinese Journal of Biotechnology]. (United States)

    Jiang, Ning


    This review addresses the association of "Chinese Journal of Biotechnology" and the development of biotechnology in China in the past 30 years. Topics include relevant awards and industrialization, development of the biotechnology discipline, and well know scientists in biotechnology, as well as perspectives on the journal.

  9. Biotechnology, nanotechnology, and pharmacogenomics and pharmaceutical compounding, Part 1. (United States)

    Allen, Loyd V


    The world of pharmaceuticals is changing rapidly as biotechnology continues to grow and nanotechnology appears on the horizon. Biotechnology is gaining in importance in extemporaneous pharmaceutical compounding, and nanotechnology and pharmacogenomics could drastically change the practice of pharmacy. This article discusses biotechnology and the factors to consider when compounding biotechnology drugs.

  10. Cognitive Works Aids for C2 Planning: Actionable Information to Support Operational Decision Making

    National Research Council Canada - National Science Library

    Wampler, Jeffrey; Whitaker, Randall; Roth, Emilie; Scott, Ronald; Stilson, Mona; Thomas-Meyers, Gina


    .... This paper describes a design for a global mission planning C2 work aid. The discussion describes a cognitive based design approach to developing work aids called Work Centered Support Systems (WCSS...

  11. MODIS-Based Products for Operational Decision Support Systems, Phase I (United States)

    National Aeronautics and Space Administration — SMH Consulting proposes to develop a web-based decision support system to assist in Rapid Assessment, Monitoring, and Management (RAMM-DSS) on a regional scale. SMH...

  12. Decision Support Tool and Simulation Testbed for Airborne Spacing and Merging in Super Dense Operations Project (United States)

    National Aeronautics and Space Administration — The key innovation in this effort is the development of a decision support tool and simulation testbed for Airborne Spacing and Merging (ASM). We focus on concepts...

  13. Operational constraints and hydrologic variability limit hydropower in supporting wind integration (United States)

    Fernandez, Alisha R.; Blumsack, Seth A.; Reed, Patrick M.


    Climate change mitigation will require rapid adoption of low-carbon energy resources. The integration of large-scale wind energy in the United States (US) will require controllable assets to balance the variability of wind energy production. Previous work has identified hydropower as an advantageous asset, due to its flexibility and low-carbon emissions production. While many dams currently provide energy and environmental services in the US and globally, we find that multi-use hydropower facilities would face significant policy conflicts if asked to store and release water to accommodate wind integration. Specifically, we develop a model simulating hydroelectric operational decisions when the electric facility is able to provide wind integration services through a mechanism that we term ‘flex reserves’. We use Kerr Dam in North Carolina as a case study, simulating operations under two alternative reservoir policies, one reflecting current policies and the other regulating flow levels to promote downstream ecosystem conservation. Even under perfect information and significant pricing incentives, Kerr Dam faces operational conflicts when providing any substantial levels of flex reserves while also maintaining releases consistent with other river management requirements. These operational conflicts are severely exacerbated during periods of drought. Increase of payments for flex reserves does not resolve these operational and policy conflicts.

  14. Integration of computerized operation support systems on a nuclear power plant environment

    International Nuclear Information System (INIS)

    Jaime, Guilherme D.G.; Almeida, Jose C.S.; Oliveira, Mauro V.


    Automation of certain tasks in a Nuclear Power Plant (NPP) control room is expected to result in reduced operators' mental workload, which may induce other benefits such as enhanced situation awareness and improved system performance. The final goal should be higher level of operational safety. Thus, recent works are increasingly assessing automation. The LABIHS compact NPP simulator, though, still operates under strictly manual printed hard-copy procedures, despite of the fact that the simulator incorporates several advancements in design of digitalized Human-Interfaces (HSIs). This work presents the development, implementation and integration of selected components to achieve increased level of computerized/automated operation of the LABIHS compact NPP simulator. Specifically, we discuss three components: (I) Automatic Plant Mode Detection, (II) Automatic Alarm Filtering, and (III) Computerized Procedures. Each one of these components has to be carefully designed/integrated so that one can avoid the undesired effects of some known implementations of automated systems on NPP, such as the reduction in the operator's system awareness, an increase in monitoring workload, and the degradation in manual skills, which could lead to automation-induced system failures. (author)

  15. A three-level support method for smooth switching of the micro-grid operation model (United States)

    Zong, Yuanyang; Gong, Dongliang; Zhang, Jianzhou; Liu, Bin; Wang, Yun


    Smooth switching of micro-grid between the grid-connected operation mode and off-grid operation mode is one of the key technologies to ensure it runs flexible and efficiently. The basic control strategy and the switching principle of micro-grid are analyzed in this paper. The reasons for the fluctuations of the voltage and the frequency in the switching process are analyzed from views of power balance and control strategy, and the operation mode switching strategy has been improved targeted. From the three aspects of controller’s current inner loop reference signal, voltage outer loop control strategy optimization and micro-grid energy balance management, a three-level security strategy for smooth switching of micro-grid operation mode is proposed. From the three aspects of controller’s current inner loop reference signal tracking, voltage outer loop control strategy optimization and micro-grid energy balance management, a three-level strategy for smooth switching of micro-grid operation mode is proposed. At last, it is proved by simulation that the proposed control strategy can make the switching process smooth and stable, the fluctuation problem of the voltage and frequency has been effectively improved.

  16. Operational constraints and hydrologic variability limit hydropower in supporting wind integration

    International Nuclear Information System (INIS)

    Fernandez, Alisha R; Blumsack, Seth A; Reed, Patrick M


    Climate change mitigation will require rapid adoption of low-carbon energy resources. The integration of large-scale wind energy in the United States (US) will require controllable assets to balance the variability of wind energy production. Previous work has identified hydropower as an advantageous asset, due to its flexibility and low-carbon emissions production. While many dams currently provide energy and environmental services in the US and globally, we find that multi-use hydropower facilities would face significant policy conflicts if asked to store and release water to accommodate wind integration. Specifically, we develop a model simulating hydroelectric operational decisions when the electric facility is able to provide wind integration services through a mechanism that we term ‘flex reserves’. We use Kerr Dam in North Carolina as a case study, simulating operations under two alternative reservoir policies, one reflecting current policies and the other regulating flow levels to promote downstream ecosystem conservation. Even under perfect information and significant pricing incentives, Kerr Dam faces operational conflicts when providing any substantial levels of flex reserves while also maintaining releases consistent with other river management requirements. These operational conflicts are severely exacerbated during periods of drought. Increase of payments for flex reserves does not resolve these operational and policy conflicts. (letter)

  17. High flux operation of microstrip gas chambers on glass and plastic supports

    International Nuclear Information System (INIS)

    Bouclier, R.; Florent, J.J.; Gaudaen, J.; Millon, G.; Pasta, A.; Ropelewski, L.; Sauli, F.; Shekhtman, L.I.


    Recent observations on microstrip gas chambers realized on various glass and plastic supports are presented in this paper. Short term measurements indicate a rate capability up to and above 5x10 5 counts/s mm 2 . A long term exposure to radiation shows however gain modifications, dependent on the resistivity of the chamber substrate; a choice of low resistivity supports minimizes this effect. (orig.)

  18. Biotechnology Education: A Multiple Instructional Strategies Approach. (United States)

    Dunham, Trey; Wells, John; White, Karissa


    Provides a rationale for inclusion of biotechnology in technology education. Describes an instructional strategy that uses behaviorist, cognitive, and constructivist learning theories in two activities involving photobioreactors and bovine somatotropin (growth hormone). (Contains 39 references.) (SK)

  19. Application of biotechnology to improve livestock products

    Directory of Open Access Journals (Sweden)

    Swati Gupta

    Full Text Available Biotechnological achievements of recent years have emerged as powerful tool to improve quality attributes of livestock products including milk and meat products. Biotechnological approaches can be employed for improving productivity, economy, physicochemical and nutritional attributes of a wide range of livestock products. The target areas of biotechnological research in the field of livestock products can be envisaged as production of high yielding food animal, improvement in quality of their products, enhanced production of natural food grade preservatives, efficient byproduct utilization and so forth. Many of the biotechnological techniques can be explored in the area of quality assurance programmes, which would be of great help to produce livestock products of assured quality and public health safety. [Vet World 2012; 5(10.000: 634-638

  20. Mechatronics design principles for biotechnology product development. (United States)

    Mandenius, Carl-Fredrik; Björkman, Mats


    Traditionally, biotechnology design has focused on the manufacture of chemicals and biologics. Still, a majority of biotechnology products that appear on the market today is the result of mechanical-electric (mechatronic) construction. For these, the biological components play decisive roles in the design solution; the biological entities are either integral parts of the design, or are transformed by the mechatronic system. This article explains how the development and production engineering design principles used for typical mechanical products can be adapted to the demands of biotechnology products, and how electronics, mechanics and biology can be integrated more successfully. We discuss three emerging areas of biotechnology in which mechatronic design principles can apply: stem cell manufacture, artificial organs, and bioreactors. Copyright 2010 Elsevier Ltd. All rights reserved.