WorldWideScience

Sample records for biosciences laboratory biosecurity

  1. A survey of Asian life scientists :the state of biosciences, laboratory biosecurity, and biosafety in Asia.

    Energy Technology Data Exchange (ETDEWEB)

    Gaudioso, Jennifer Marie

    2006-02-01

    Over 300 Asian life scientists were surveyed to provide insight into work with infectious agents. This report provides the reader with a more complete understanding of the current practices employed to study infectious agents by laboratories located in Asian countries--segmented by level of biotechnology sophistication. The respondents have a variety of research objectives and study over 60 different pathogens and toxins. Many of the respondents indicated that their work was hampered by lack of adequate resources and the difficulty of accessing critical resources. The survey results also demonstrate that there appears to be better awareness of laboratory biosafety issues compared to laboratory biosecurity. Perhaps not surprisingly, many of these researchers work with pathogens and toxins under less stringent laboratory biosafety and biosecurity conditions than would be typical for laboratories in the West.

  2. Auditing laboratory rodent biosecurity programs.

    Science.gov (United States)

    Porter, William P; Horn, Mandy J; Cooper, Dale M; Klein, Hilton J

    2013-10-22

    A rodent biosecurity program that includes periodic evaluation of procedures used in an institution's vivarium can be used to ensure that best practices are in place to prevent a microbial pathogen outbreak. As a result of an ongoing comprehensive biosecurity review within their North American and European production facilities, the authors developed a novel biosecurity auditing process and worksheet that could be useful in other animal care and use operations. The authors encourage other institutions to consider initiating similar audits of their biosecurity programs to protect the health of their laboratory animals. PMID:24150170

  3. Laboratory biorisk management biosafety and biosecurity

    CERN Document Server

    Salerno, Reynolds M

    2015-01-01

    Over the past two decades bioscience facilities worldwide have experienced multiple safety and security incidents, including many notable incidents at so-called ""sophisticated facilities"" in North America and Western Europe. This demonstrates that a system based solely on biosafety levels and security regulations may not be sufficient.Setting the stage for a substantively different approach for managing the risks of working with biological agents in laboratories, Laboratory Biorisk Management: Biosafety and Biosecurity introduces the concept of biorisk management-a new paradigm that encompas

  4. International biosecurity symposium : securing high consequence pathogens and toxins : symposium summary.

    Energy Technology Data Exchange (ETDEWEB)

    2004-06-01

    The National Nuclear Security Administration (NNSA) Office of Nonproliferation Policy sponsored an international biosecurity symposium at Sandia National Laboratories (SNL). The event, entitled 'Securing High Consequence Pathogens and Toxins', took place from February 1 to February 6, 2004 and was hosted by Dr. Reynolds M. Salerno, Principal Member of the Technical Staff and Program Manager of the Biosecurity program at Sandia. Over 60 bioscience and policy experts from 14 countries gathered to discuss biosecurity, a strategy aimed at preventing the theft and sabotage of dangerous pathogens and toxins from bioscience facilities. Presentations delivered during the symposium were interspersed with targeted discussions that elucidated, among other things, the need for subsequent regional workshops on biosecurity, and a desire for additional work toward developing international biosecurity guidelines.

  5. Reflective Practice: A Place in Enhancing Learning in the Undergraduate Bioscience Teaching Laboratory?

    Science.gov (United States)

    Parry, Damian; Walsh, Cathy; Larsen, Carl; Hogan, Joanne

    2012-01-01

    Bioscience employers demand graduates with better practical competence. It is our supposition that, although undesirable, student learning is assessment driven and this is leading students to simply go through the motions in the practical setting (whether field work or laboratory based). In this intervention a Critical Incident Report was…

  6. Communicating biosecurity.

    Science.gov (United States)

    Briggs, Charles L

    2011-01-01

    Shifting from risk-calculation orientations focusing on populations to preparedness perspectives that model uncertainty through scenario-based projections, biosecurity debates redefined notions of "health" and "security." Nevertheless, a key focus of biosecurity discussions--the domain labeled "communication"--has not been fundamentally rethought, even as it has expanded and professionalized. Bracketing preconceived ideas about the term's content, the article traces debates about biosecurity "communication" from the 1990s to the present, drawing on ethnography and textual analysis. Using a notion of biocommunicability, the cultural modeling of how discourse is produced, circulates, and is received, the article analyzes assumptions regarding subjects, subject-positions, objects, spatializing and temporalizing practices, scales, economies of affect, and regimes of ethics that are built into discourse about "communication." Ironically, the conviction that "communication" is of marginal importance as a focus of critical inquiry, seemingly shared by most medical anthropologists, enables these assumptions to fundamentally shape discussions of biosecurity and emergency management.

  7. Writing Activities Embedded in Bioscience Laboratory Courses to Change Students' Attitudes and Enhance Their Scientific Writing

    Science.gov (United States)

    Lee, Susan E.; Woods, Kyra J.; Tonissen, Kathryn F.

    2011-01-01

    We introduced writing activities into a project style third year undergraduate biomolecular science laboratory to assist the students to produce a final report in the form of a journal article. To encourage writing while the experimental work was proceeding, the embedded writing activities required ongoing analysis of experimental data. After…

  8. The Model Laboratory Animal and the‘Trojan Horse' in Biosecurity

    Institute of Scientific and Technical Information of China (English)

    Stephen Driver

    2003-01-01

    @@ Today's sophisticated biomedical research sometimes requires the use of laboratory animals raised in stable micronen vironments free from the microorganisms that may compromise the success of an experiment. Laboratory rodents can be obtained in one of several categories defined by the degree to which they harbour microflora, whether commensal, potentially pathogenic or pathogenic. It is now possible to specify the different species of organism that are tolerated and those that are not tolerated, In such model laboratory animals it is essential to raise and maintain them in circumstances under which microorganisms that would not be tolerated cannot enter the production system.

  9. Autonomous surveillance for biosecurity.

    Science.gov (United States)

    Jurdak, Raja; Elfes, Alberto; Kusy, Branislav; Tews, Ashley; Hu, Wen; Hernandez, Emili; Kottege, Navinda; Sikka, Pavan

    2015-04-01

    The global movement of people and goods has increased the risk of biosecurity threats and their potential to incur large economic, social, and environmental costs. Conventional manual biosecurity surveillance methods are limited by their scalability in space and time. This article focuses on autonomous surveillance systems, comprising sensor networks, robots, and intelligent algorithms, and their applicability to biosecurity threats. We discuss the spatial and temporal attributes of autonomous surveillance technologies and map them to three broad categories of biosecurity threat: (i) vector-borne diseases; (ii) plant pests; and (iii) aquatic pests. Our discussion reveals a broad range of opportunities to serve biosecurity needs through autonomous surveillance. PMID:25744760

  10. Synthetic biology and biosecurity.

    Science.gov (United States)

    Robienski, Jürgen; Simon, Jürgen

    2014-01-01

    This article discusses the conflict fields and legal questions of synthetic biology, esp. concerning biosecurity. A respective jurisprudential discussion has not taken place yet in Germany apart from few statements and recommendations. But in Germany, Europe and the USA, it is generally accepted that a broad discussion is necessary. This is esp. true for the question of biosecurity and the possible dangers arising from Synthetic Biology. PMID:25845204

  11. MENGAPA BIOSECURITY MENJADI PENTING PADA LABORATORIUM PENYAKIT INFEKSI ?

    Directory of Open Access Journals (Sweden)

    Frans X Suharyanto Halim

    2012-08-01

    Full Text Available Abstract . Laboratory biosecurity is the protection, control and accountability for valuable biological material ( VBM laboratories, in order to prevent their unauthorized access, loss, theft, misuse, diversion or intentional release. The efforts of biosecurity have capability to anticipate the potential probability of releasing biohazard agent from the laboratory, the risk assessment study in the infectious disease laboratories was an effort to know whether biosecurity measures were applied in the laboratory. The usage of modified checklist questionnaire of biosecurity for collecting data and observation was done to identify potential hazard in the infectious disease laboratories according to the conceptional framework of agent, host and environmental principal. The places of this assessment are in the five regional referral infectious disease laboratories , i.e., Universitas Islam Sumatera Utara (UISU Medan, Universitas Indonesia (UI - Jakarta, Balai Pengembangan Laboratorium Kesehatan (BPLK - Bandung, Universitas Diponegoro (UNDIP - Semarang , Universitas Hasanudin (UNHAS - Makassar, one referral hospital , i.e., Rumah Sakit Umum Daerah (RSUD - Tangerang and one national referral laboratory of Center for Biomedical and Pharmaceutical Research and Development, National Institute of Health Research and Development ( NIHRD, Ministry of Health (MOH, Jakarta. The risk assessment study was done in year 2008-2009. Physical security, personnel management and information security as components of biosecurity were not applied properly in the 7 infectious disease laboratories. Applying biosecurity in the infectious disease laboratories was very important and need to be done completely to anticipate their unauthorized access, loss, theft, misuse, diversion or intentional release.Keywords : biosecurity,   bioterrorism , infectious disease laboratory, and valuable biological materials (VBM

  12. APTASENSORS FOR BIOSECURITY APPLICATIONS

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, N; Tarasow, T; Tok, J

    2007-01-03

    Nucleic acid aptamers have found steadily increased utility and application steadily over the last decade. In particular, aptamers have been touted as a valuable complement to and in some cases replacement for antibodies due to their structural and functional robustness as well as their ease in generation and synthesis. They are thus attractive for biosecurity applications, e.g. pathogen detection, and are especially well suited since their in vitro generation process does not require infection of any host systems. Herein we provide a brief overview of the aptamers generated against biopathogens over the last few years. In addition, a few recently described detection platforms using aptamers (aptasensors) and potentially suitable for biosecurity applications will be discussed.

  13. Biosecurity's unruly spaces.

    Science.gov (United States)

    Mather, Charles; Marshall, Amy

    2011-01-01

    This paper is about the geopolitics of animal health governance. Through a biosecurity event in South Africa's pig sector we examine changes in the way the governance of disease risk is configuring intra-national spaces. Our case suggests an emerging geopolitics of animal health, one that is defined not by differences between nations but by a more complex patchwork of ‘secure’ and ‘unruly spaces’. PMID:22180920

  14. LabTrove: A Lightweight, Web Based, Laboratory “Blog” as a Route towards a Marked Up Record of Work in a Bioscience Research Laboratory

    OpenAIRE

    Milsted, Andrew J.; Hale, Jennifer R.; Frey, Jeremy G.; Cameron Neylon

    2013-01-01

    Background The electronic laboratory notebook (ELN) has the potential to replace the paper notebook with a marked-up digital record that can be searched and shared. However, it is a challenge to achieve these benefits without losing the usability and flexibility of traditional paper notebooks. We investigate a blog-based platform that addresses the issues associated with the development of a flexible system for recording scientific research. Methodology/Principal Findings We chose...

  15. Why biosecurity matters: students' knowledge of biosecurity and implications for future engagement with biosecurity initiatives

    Science.gov (United States)

    Ram, Rajesh; France, Bev; Birdsall, Sally

    2016-01-01

    Background: Research on biosecurity is important as New Zealand's agricultural export-driven economy is susceptible to biosecurity threats. Because New Zealand is reliant on the primary industries to drive its economy, bovine diseases such as foot and mouth could have a devastating effect on the economy. Purpose: Making sure that the general public are aware of the importance of maintaining biosecurity is crucial in order to protect New Zealand's economy, human health, the environment, and social and cultural values. New Zealand Year 9 students' knowledge of biosecurity was gauged as these students represented the next generation of individuals tasked to maintain biosecurity in New Zealand. Design: A qualitative approach using the interpretive mode of inquiry was used to investigate the knowledge about biosecurity with New Zealand Year 9 students. Questionnaires and interviews were the data collection tools. Sample: One hundred and seventy-one students completed a questionnaire that consisted of Likert-type questions and open-ended questions. Nine students were interviewed about their knowledge. Results: The findings showed that New Zealand Year 9 students lacked specific knowledge about unwanted plants, animals and microorganisms. These students saw illicit drug plants as unwanted plants and mainly saw possums as unwanted animals in New Zealand. Their knowledge about unwanted microorganisms in New Zealand was dominated by human-disease-causing microbes. A lack of knowledge of biosecurity issues in New Zealand was seen as the major factor in these students limited understanding of biosecurity. Conclusions: Based on these findings, it can be said that knowledge of an issue is critical in enabling individuals to develop an understanding about biosecurity. Explicit teaching of biosecurity-related curriculum topics could provide New Zealand Year 9 students with an opportunity to develop knowledge about biosecurity in New Zealand.

  16. Why Biosecurity Matters: Students' Knowledge of Biosecurity and Implications for Future Engagement with Biosecurity Initiatives

    Science.gov (United States)

    Ram, Rajesh; France, Bev; Birdsall, Sally

    2016-01-01

    Background: Research on biosecurity is important as New Zealand's agricultural export-driven economy is susceptible to biosecurity threats. Because New Zealand is reliant on the primary industries to drive its economy, bovine diseases such as foot and mouth could have a devastating effect on the economy. Purpose: Making sure that the general…

  17. Synchrotron radiation in biosciences

    Science.gov (United States)

    Marinkovic, Nebojsa S.; Gupta, Sayan; Zhan, Chenyang; Chance, Mark R.

    2005-12-01

    The Center for Synchrotron Biosciences (CSB) operates five beamlines at the National Synchrotron Light Source (NSLS). Infrared (IR) micro-spectroscopy, X-ray absorption spectroscopy, structural proteomics and macromolecular footprinting are among the major technologies available through the Center. IR micro-spectroscopy is used to examine protein-folding in the microsecond time regime, image bone, neurons, seeds and other biological tissues, as well as image samples of interest in the chemical and environmental sciences. Structural proteomics research of New York Structural Genomics Research Consortium (NYSGRC) is steadily increasing the number of solved protein structures, with a goal to solve 100-200 structures per year. To speed up the research, a high-throughput method called 'metallomics' was implemented for NYSGRC crystallographers to detect intrinsic anomalous scatterers using X-ray absorption spectroscopy. Hydroxyl radical mediated X-ray footprinting is capable of resolving folding events of RNA, at single base resolution on millisecond timescales using a synchrotron white beam. The high brightness of synchrotron source is essential for CSB projects as it permits the use of smaller sample sizes and/or concentration, and allows studies of more complicated biological systems than with conventional sources.

  18. Synchrotron radiation in biosciences

    Energy Technology Data Exchange (ETDEWEB)

    Marinkovic, Nebojsa S. [Center for Synchrotron Biosciences, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Ullman 315, Bronx, NY 10461 (United States)]. E-mail: marinkov@bnl.gov; Gupta, Sayan [Center for Synchrotron Biosciences, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Ullman 315, Bronx, NY 10461 (United States); Zhan, Chenyang [Center for Synchrotron Biosciences, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Ullman 315, Bronx, NY 10461 (United States); Chance, Mark R. [Center for Synchrotron Biosciences, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Ullman 315, Bronx, NY 10461 (United States)

    2005-12-15

    The Center for Synchrotron Biosciences (CSB) operates five beamlines at the National Synchrotron Light Source (NSLS). Infrared (IR) micro-spectroscopy, X-ray absorption spectroscopy, structural proteomics and macromolecular footprinting are among the major technologies available through the Center. IR micro-spectroscopy is used to examine protein-folding in the microsecond time regime, image bone, neurons, seeds and other biological tissues, as well as image samples of interest in the chemical and environmental sciences. Structural proteomics research of New York Structural Genomics Research Consortium (NYSGRC) is steadily increasing the number of solved protein structures, with a goal to solve 100-200 structures per year. To speed up the research, a high-throughput method called 'metallomics' was implemented for NYSGRC crystallographers to detect intrinsic anomalous scatterers using X-ray absorption spectroscopy. Hydroxyl radical mediated X-ray footprinting is capable of resolving folding events of RNA, at single base resolution on millisecond timescales using a synchrotron white beam. The high brightness of synchrotron source is essential for CSB projects as it permits the use of smaller sample sizes and/or concentration, and allows studies of more complicated biological systems than with conventional sources.

  19. Environmental Biosciences Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2007-01-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the DOE. Plans for restructuring the performance schedule of the trichloroethylene projects have been submitted to the department. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this

  20. Implementation of a personnel reliability program as a facilitator of biosafety and biosecurity culture in BSL-3 and BSL-4 laboratories.

    Science.gov (United States)

    Higgins, Jacki J; Weaver, Patrick; Fitch, J Patrick; Johnson, Barbara; Pearl, R Marene

    2013-06-01

    In late 2010, the National Biodefense Analysis and Countermeasures Center (NBACC) implemented a Personnel Reliability Program (PRP) with the goal of enabling active participation by its staff to drive and improve the biosafety and biosecurity culture at the organization. A philosophical keystone for accomplishment of NBACC's scientific mission is simultaneous excellence in operations and outreach. Its personnel reliability program builds on this approach to: (1) enable and support a culture of responsibility based on human performance principles, (2) maintain compliance with regulations, and (3) address the risk associated with the insider threat. Recently, the Code of Federal Regulations (CFR) governing use and possession of biological select agents and toxins (BSAT) was amended to require a pre-access suitability assessment and ongoing evaluation for staff accessing Tier 1 BSAT. These 2 new requirements are in addition to the already required Federal Bureau of Investigation (FBI) Security Risk Assessment (SRA). Two years prior to the release of these guidelines, NBACC developed its PRP to supplement the SRA requirement as a means to empower personnel and foster an operational environment where any and all work with BSAT is conducted in a safe, secure, and reliable manner.

  1. [Bioterrorism, parasites as potential bioterrorism agents and biosecurity studies].

    Science.gov (United States)

    Aksoy, Umit

    2006-01-01

    A variety of agents have a potential risk for being use as weapons of biological terrorism. However, the use of parasites as bioterrorism agents has not received so much attention. Parasites could contribute to the installation of fear in human population upon intentional addition to their food and water supplies. On the other hand, vector-borne parasites can also constitute risk of bioterrorism. Biosecurity issues are gaining importance as a consequence of globalization. Surveillance is critical in maintaining biosecurity and early detection of infectious disease agents is essential. In this review article, bioterrorism, the role of parasites as potential bioterrorism agents, studies on biosecurity and laboratory design for biosafety have been discussed under the light of recent literature.

  2. Adaptive approaches to biosecurity governance.

    Science.gov (United States)

    Cook, David C; Liu, Shuang; Murphy, Brendan; Lonsdale, W Mark

    2010-09-01

    This article discusses institutional changes that may facilitate an adaptive approach to biosecurity risk management where governance is viewed as a multidisciplinary, interactive experiment acknowledging uncertainty. Using the principles of adaptive governance, evolved from institutional theory, we explore how the concepts of lateral information flows, incentive alignment, and policy experimentation might shape Australia's invasive species defense mechanisms. We suggest design principles for biosecurity policies emphasizing overlapping complementary response capabilities and the sharing of invasive species risks via a polycentric system of governance. PMID:20561262

  3. ADOPTION OF BIOSECURITY MEASURES BY LAYER SMALLHOLDERS

    Directory of Open Access Journals (Sweden)

    V. S. Lestari

    2011-12-01

    Full Text Available It was indicated that layer smallholders awareness of biosecurity was low. This paper aimed to determine the level of adoption within the South Sulawesi layer smallholders of a range of standard biosecurity measures. Sidenreng Rappang (Sidrap regency was chosen as a location of the research, because it was famous as a central of layer smallholders. Total sample was 60 respondents. The sample was chosen through random sampling from two districts which were the most populous of layer smallholders, namely Baranti and Maritengae. Data were collected using structured questionnaires and depth-interview. The data were tabulated and analysed using a simple method of scoring with regard to their biosecurity status. The status of biosecurity was used to know the level of biosecurity adoption. Biosecurity status was obtained based on the adoption of biosecurity measures which consisted of 9 stages: farm inputs, traffic onto farms, distance from sources of pathogens to shed, exposure of farm, biosecurity at farm boundary, biosecurity between farm boundary and shed, biosecurity at the shed door, traffic into the shed and susceptibility of the flock. Using adoption index, this research revealed that biosecurity adoption of layer smallholders in South Sulawesi was classified into a partial adopter.

  4. Biosecurity and trade in a global market place

    International Nuclear Information System (INIS)

    Full text: International travel and free trade are modern bywords and the international movement of people, animals and livestock products seen essential for the global market place to function. Yet is this compatible with a bio-secure national environment? Governments around the world seek to manage the risk posed by infectious disease on livestock, man, the environment and the related ecosystems whilst at the same time permit free trade. Ample examples exist of these competing elements as illustrated by recent outbreaks of Avian Influenza, bluetongue, SARS and most recently in Australia, equine influenza. Whilst the recognition that some 70% of new infectious diseases in man come from animals even those diseases that affect only animals, such as Foot and Mouth disease, can have devastating effects on trade and economies. The word 'biosecurity' now encompasses most of these elements with processes being developed to identify these biosecurity risks, to mitigate or eliminate the risks and to ultimately prevent adverse biosecurity events. An added dimension to be recently considered is that of bioterrorism. The OIE or World Animal Health Organisation was established in 1924 to address the risks posed by trade in animals and their products but the biosecurity issues we now face seem well beyond the initial remit of this Organisation. The World Health Organisation has for many years provided a public health framework to address zoonotic infections but again many aspects of biosecurity goes well outside this remit. The Food and Agricultural Organisation, often in partnership with OIE and WHO have sought to provide processes for identifying and managing biosecurity but often on a disease by disease basis, or in response to disease emergency. The Joint FAO/IAEA Division has contributed much through setting standards and developing a quality assurance system for laboratories, which provides critical underpinning data. But even together is this enough to manage the

  5. Biosecurity for highly pathogenic avian influenza

    OpenAIRE

    2015-01-01

    This paper describes in detail the current situation and state of knowledge about biosecurity in relation to H5N1 HPAI, discusses species- and sector-specific issues, proposes possible options for biosecurity in important parts of the domestic poultry and captive bird sector, stresses the importance of situating biosecurity in appropriate economic and culture settings, and makes the case for the role of communication.--Publisher's description.

  6. Environmental Biosciences Program Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2009-01-30

    Current research projects have focused Environmental Biosciences Program (EBP) talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene, low-dose ionizing radiation (gamma and neutron) and alpha radiation from plutonium. Trichloroethylene research has been conducted as a joint collaborative effort with the University of Georgia. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the United States Department of Energy (DOE). Laboratory work has been completed on several trichloroethylene risk assessment projects, and these projects have been brought to a close. Plans for restructuring the performance schedule of the remaining trichloroethylene projects have been submitted to the department. A comprehensive manuscript on the scientific basis of trichloroethylene risk assessment is in preparation. Work on the low-dose radiation risk assessment projects is also progressing at a slowed rate as a result of funding uncertainties. It has been necessary to restructure the proponency and performance schedule of these projects, with the project on Low-Dose Radiation: Epidemiology Risk Models transferred to DOE Office of Science proponency under a separate funding instrument. Research on this project will continue under the provisions of the DOE Office of Science funding instrument, with progress reported in accordance with the requirements of that funding instrument. Progress on that project will no longer be reported in quarterly reports for DE-FC09-02CH11109. Following a meeting at the Savannah River Site on May 8, 2008, a plan was submitted for development of an epidemiological cohort study and prospective medical surveillance system for the assessment of disease rates among workers at the Savannah River

  7. ADOPTION OF BIOSECURITY MEASURES BY LAYER SMALLHOLDERS

    Directory of Open Access Journals (Sweden)

    V.S. Lestari

    2014-10-01

    Full Text Available It was indicated that layer smallholders awareness of biosecurity was low. This paper aimed todetermine the level of adoption within the South Sulawesi layer smallholders of a range of standardbiosecurity measures. Sidenreng Rappang (Sidrap regency was chosen as a location of the research,because it was famous as a central of layer smallholders. Total sample was 60 respondents. The samplewas chosen through random sampling from two districts which were the most populous of layersmallholders, namely Baranti and Maritengae. Data were collected using structured questionnaires anddepth-interview. The data were tabulated and analysed using a simple method of scoring with regard totheir biosecurity status. The status of biosecurity was used to know the level of biosecurity adoption.Biosecurity status was obtained based on the adoption of biosecurity measures which consisted of 9stages: farm inputs, traffic onto farms, distance from sources of pathogens to shed, exposure of farm,biosecurity at farm boundary, biosecurity between farm boundary and shed, biosecurity at the shed door,traffic into the shed and susceptibility of the flock. Using adoption index, this research revealed thatbiosecurity adoption of layer smallholders in South Sulawesi was classified into a “partial adopter”.

  8. Synthetic biology and biosecurity: challenging the "myths".

    Science.gov (United States)

    Jefferson, Catherine; Lentzos, Filippa; Marris, Claire

    2014-01-01

    Synthetic biology, a field that aims to "make biology easier to engineer," is routinely described as leading to an increase in the "dual-use" threat, i.e., the potential for the same scientific research to be "used" for peaceful purposes or "misused" for warfare or terrorism. Fears have been expressed that the "de-skilling" of biology, combined with online access to the genomic DNA sequences of pathogenic organisms and the reduction in price for DNA synthesis, will make biology increasingly accessible to people operating outside well-equipped professional research laboratories, including people with malevolent intentions. The emergence of do-it-yourself (DIY) biology communities and of the student iGEM competition has come to epitomize this supposed trend toward greater ease of access and the associated potential threat from rogue actors. In this article, we identify five "myths" that permeate discussions about synthetic biology and biosecurity, and argue that they embody misleading assumptions about both synthetic biology and bioterrorism. We demonstrate how these myths are challenged by more realistic understandings of the scientific research currently being conducted in both professional and DIY laboratories, and by an analysis of historical cases of bioterrorism. We show that the importance of tacit knowledge is commonly overlooked in the dominant narrative: the focus is on access to biological materials and digital information, rather than on human practices and institutional dimensions. As a result, public discourse on synthetic biology and biosecurity tends to portray speculative scenarios about the future as realities in the present or the near future, when this is not warranted. We suggest that these "myths" play an important role in defining synthetic biology as a "promissory" field of research and as an "emerging technology" in need of governance. PMID:25191649

  9. Biosecurity in 121 Danish sow herds

    DEFF Research Database (Denmark)

    Boklund, Anette; Mortensen, Sten; Houe, H.

    2003-01-01

    Herds are under constant risk of introducing new pathogens from different sources. In this article we describe biosecurity practices in Danish sow herds. Between December 1, 1999 and February 29, 2000, 121 sow units were interviewed regarding biosecurity on the site. The questionnaire contained 6...

  10. Biosecurity and globalising economic spaces

    Directory of Open Access Journals (Sweden)

    Charles Mather

    2012-01-01

    Full Text Available This chapter is concerned with the global regulation of animal health. Our case is a recent outbreak of avian influenza in South Africa’s ostrich industry. The analysis confirms an important theme in the emerging social sciences literature on biosecurity, i.e. the paradox of control methods that are rigid and inflexible, and diseases that are indeterminate. We also examine a second approach to the outbreak that relied on local experience and knowledge. Our chapter explores the complex ways in which globalizing economic spaces are integrated into new global regulatory regimes, with important implications for economic, social and geographical processes.

  11. Biosecurity Plan for Palmyra Atoll

    Science.gov (United States)

    Hathaway, Stacie A.; Fisher, Robert N.

    2010-01-01

    This Biosecurity Plan for Palmyra Atoll was developed for The Nature Conservancy (TNC) Palmyra Program to refine and expand goals and objectives developed through the Conservation Action Plan process. The Biosecurity Plan is one in a series of adaptive management plans designed to achieve TNC's mission toward the protection and enhancement of native wildlife and habitat. The Biosecurity Plan focuses on ecosystem security, and specifically identifies and addresses issues related to non-native and potentially invasive species. The Plan attempts to identify pathways of invasion and strategies for preventing or reducing new introductions. Overall, the Biosecurity Plan provides a framework to implement and track the progress of conservation and restoration goals related to non-native species on Palmyra Atoll. Palmyra Atoll is one of the Northern Line Islands in the Pacific Ocean southwest of the Hawai`ian Islands. It consists of many heavily vegetated islets arranged in a horseshoe pattern around four lagoons and surrounded by a coral reef. At present, Palmyra Atoll harbors various non-native or invasive species in the terrestrial and marine ecosystems. The most notable examples of terrestrial invasive species include coconut trees (Cocos nucifera) and black rats (Rattus rattus). Although it is unclear whether they are non-native, coconut trees are currently the most dominant plant across Palmyra Atoll. They compete with native plant species for space and resources, and are potentially detrimental to seabirds dependent on native vegetation. Black rats are known to predate ground-nesting seabirds and are likely responsible for the lack of burrowing seabird reproduction on Palmyra Atoll. The most notable example of a marine invasive species is the corallimorph (Rhodactis howsei). Although Rhodactis howsei is a native species, it can take advantage of human-altered habitat and significantly change the natural habitat by aggressively outcompeting native corals. Although the

  12. 76 FR 18770 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2011-04-05

    ...-202-2783 (Formerly: Forensic Toxicology Laboratory Baptist Medical Center). Clinical Reference Lab...Kline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories). Quest Diagnostics... Clinical Laboratories; SmithKline Bio-Science Laboratories). Quest Diagnostics Incorporated, 8401...

  13. 75 FR 67749 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2010-11-03

    ...-202-2783 (Formerly: Forensic Toxicology Laboratory Baptist Medical Center). Clinical Reference Lab...Kline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories). Quest Diagnostics... Clinical Laboratories; SmithKline Bio-Science Laboratories). Quest Diagnostics Incorporated, 8401...

  14. Implementing Biosecurity Education: Approaches, Resources and Programmes

    OpenAIRE

    Minehata, Masamichi; Sture, Judi; Shinomiya, Nariyoshi; Whitby, Simon

    2011-01-01

    This paper aims to present possible approaches, resources and programmes to introduce the topic of biosecurity to life scientists and engineers at the higher education level. Firstly, we summarise key findings from a number of international surveys on biosecurity education that have been carried out in the United States, Europe, Israel and the Asia–Pacific region. Secondly, we describe the development of our openly-accessible education resource, illustrating the scope and content of these mat...

  15. Environmental Biosciences First Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2003-09-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risk issues. These initiatives are consistent with the Medical University's role as a comprehensive state-supported health sciences institution and the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable the Medical University to be a national resource for the scientific investigation of environmental health issues. EBP's success in convening worldwide scientific expertise is due in part to the inherent credibility the Medical University brings to the process of addressing these complex issues. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), asbestos and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  16. Environmental Biosciences Program Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2007-07-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the DOE. Plans for restructuring the performance schedule of the trichloroethylene projects have been submitted to the department. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this

  17. Environmental Biosciences Program Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2006-10-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this cooperative agreement can be forwarded to Dr. Lawrence C. Mohr in the EBP office of the Medical University of South Carolina at (843) 792-1532.

  18. Environmental Biosciences Program Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2008-01-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the DOE. Plans for restructuring the performance schedule of the trichloroethylene projects have been submitted to the department. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  19. Protecting US cattle. The role of national biosecurity programs.

    Science.gov (United States)

    Hueston, William D; Taylor, Jared D

    2002-03-01

    The bovine practitioner has a critical role to play in promoting biosecurity at both the farm level and the national level. Successful exclusion of exotic diseases, biocontainment of endemic diseases, and emergency preparedness rest soundly on bovine practitioners as part of the national biosecurity team. Bovine practitioners must voice their opinions on the strengths and weaknesses of existing and proposed national biosecurity programs. Healthy debate about national biosecurity programs and consideration of biosecurity issues by national veterinary organizations provide valuable feedback for the continual improvement of the programs and enhance their credibility. The health and productivity of US agriculture depend on national biosecurity.

  20. Biosecurity in a global market place

    International Nuclear Information System (INIS)

    International travel and free trade are modern bywords and the international movement of people, animals and livestock products seen as essential for the global market place to function. Yet is this compatible with a national bio-secure environment? Governments around the world seek to manage the risks posed by infectious disease to livestock, man, the environment and related ecosystems whilst at the same time permitting free trade. Ample examples exist of these competing elements as illustrated by recent outbreaks of avian influenza, bluetongue, severe acute respiratory syndrome (SARS) and most recently in Australia, equine influenza. Whilst the recognition that some 70% of new infectious diseases in man come from animals, even those diseases that affect only animals such as foot and mouth disease, can have devastating effects on trade and economies. The word 'biosecurity' now encompasses most of these elements with processes being developed to identify, mitigate or eliminate these biosecurity risks, and ultimately to prevent adverse events. An added dimension to be considered recently is that of bio-terrorism. So is it time for a new global co-ordinated and collaborative approach to managing biosecurity that recognises the need to encourage not restrict, the global market place? Are there newer approaches that could encourage global trade in livestock and livestock products? One such strategy could be to consider the biosecurity risks of the commodity as opposed to the disease status of the country of origin as a more effective approach for the future. (author)

  1. Implementing Biosecurity Education: Approaches, Resources and Programmes

    Science.gov (United States)

    Minehata, Masamichi; Sture, Judi; Shinomiya, Nariyoshi; Whitby, Simon

    2016-01-01

    This paper aims to present possible approaches, resources and programmes to introduce the topic of biosecurity to life scientists and engineers at the higher education level. Firstly, we summarise key findings from a number of international surveys on biosecurity education that have been carried out in the United States, Europe, Israel and the Asia–Pacific region. Secondly, we describe the development of our openly-accessible education resource, illustrating the scope and content of these materials. Thirdly, we report on actual cases of biosecurity education that have been implemented. These include achievements in and lessons derived from the implementation of biosecurity education at the National Defense Medical College in Japan. These experiences are followed by presentation of the expert-level “Train-the-Trainer” programmes subsequently launched by the University of Bradford in the United Kingdom. These examples will help readers to understand how educators can enhance their own understanding about biosecurity issues and how they can then disseminate their knowledge through development of their own customised, relevantly-targeted and stage-tailored education programmes within their own life science communities. By providing these examples, we argue that education for life scientists, policy-makers and other stakeholders about social responsibility on dual-use issues is easily achievable and need not be expensive, time-consuming or over-burdening. We suggest that recurring classes or courses be held at appropriate times during educational programmes to accommodate the developing expertise and advancing learning stages of students. PMID:22038099

  2. Tilapia Vaccines: Important Disease Prevention, Biosecurity Tools

    Science.gov (United States)

    Minimizing the effects of disease is crucial to prevent mortality, morbidity and to promote rapid growth and optimal feed conversion of tilapia cultured in fresh, estuarine and marine waters. Vaccination, a valuable biosecurity safeguard, can protect tilapia against infectious diseases. Vaccinat...

  3. Nitrogen-15 reference book: medicine and biosciences

    International Nuclear Information System (INIS)

    A comprehensive bibliography on the application of the stable nitrogen isotope 15N in medicine, animal nutrition and physiology, biosciences, and related disciplines is presented. The literature pertaining to this paper covers the period from 1977 to 1981. The references are completed by an index of all authors and a subject index with special emphasis to the used organisms, labelled compounds, and tracer techniques, respectively. (author)

  4. The Application of Magnetic Techniques in Biosciences

    OpenAIRE

    Safarikova, M.; Safarik, I.

    2001-01-01

    The idea to use magnetic techniques in biosciences is not new, but it has enjoyed a resurgence of interest especially during the last two decades. Magnetic adsorbents, carriers and modifiers can be used for the immobilization, isolation, modification, detection, determination and removal of a variety of biologically active compounds, xenobiotics, cellular components and cells. Magnetic separation and labelling have recently found many useful and interesting applications in various areas of bi...

  5. On nonstandard finite difference schemes in biosciences

    Science.gov (United States)

    Anguelov, R.; Dumont, Y.; Lubuma, J. M.-S.

    2012-10-01

    We design, analyze and implement nonstandard finite difference (NSFD) schemes for some differential models in biosciences. The NSFD schemes are reliable in three directions. They are topologically dynamically consistent for onedimensional models. They can replicate the global asymptotic stability of the disease-free equilibrium of the MSEIR model in epidemiology whenever the basic reproduction number is less than 1. They preserve the positivity and boundedness property of solutions of advection-reaction and reaction-diffusion equations.

  6. FACTORS INFLUENCING BIOSECURITY ADOPTION ON LAYING HEN FARMERS

    Directory of Open Access Journals (Sweden)

    V.S. Lestari

    2012-12-01

    Full Text Available The present study was undertaken to identify factors that influences biosecurity adoption on laying hen farmers in Sidrap district, South Sulawesi. This district was choosen because beside it was famous as the center of laying hen farms, it was also as one of districts in South Sulawesi which suffered from Avian influenza outbreak. Total samples were 60 respondents. The samples were choosen through stratified random sampling from two subdistricts which had the most populous of layer smallholders, namely Baranti and Maritengngae. Data were obtained through observations and interviews using a questionnaire. Data were analyzed using a score based on biosecurity status. Biosecurity status was obtained based on the adoption of biosecurity measures which consisted of 9 stages: farm inputs, traffic onto farms, distance from sources of pathogens to shed, exposure of farm, biosecurity at farm boundary, biosecurity between farm boundary and shed, biosecurity at the shed door, traffic into the shed and susceptibility of the flock. Multiple regression model was employed to analyze the data. The study revealed that the adoption biosecurity were associated with gender, age, education, farming experience, farm-income, family size and social capital. These variables contributed 20% variation in biosecurity adoption of laying hen farms. However, only farm income, family size and social capital were the major factors influencing to the adoption of biosecurity (P<0.05.

  7. Developing Research Capabilities in Energy Biosciences

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Donald D

    2008-01-01

    Scientists founded the Life Sciences Research Foundation (LSRF) in 1983 as a non-profit pass through foundation that awards post doctoral fellowships in all areas of the life sciences. LSRF scientists review hundreds of applications each year from PhDs seeking support. For example this year, our 26th, we received 800 applications and our peer review committee will choose about 50 finalists who are eligible for these awards. We have no endowment so we solicit sponsors each year. The fellowships are sponsored by research oriented companies, foundations, philanthropists, the Howard Hughes Medical Institute, and other organizations who believe in the value of awarding fellowships to the best and the brightest young scientists. Our web site has a complete listing of all details about LSRF (http://www.lsrf.org/). In the late 1980s the Division of Bioscience in the Office of Basic Energy Science, a granting agency of the Department of Energy, joined this partnership. Bioscience's mandate was to support non-medical microbiology and plant sciences. LSRF received a series of 5 year grants from DOE to award fellowships to our top applicants in these fields of research. We began to support DOE-Energy Bioscience post doctoral fellows in 1989. From 1989 through 2004 when DOE funding ended our partnership awarded 41 DOE-Energy Bioscience Fellows of the Life Sciences Research Foundation. Each of these was a three year fellowship. DOE-Energy Biosciences was well matched with LSRF. Our extensive peer review screened applicants in all areas of the life sciences. Most LSRF sponsors are interested in supporting fellows who work on diseases. At the time that we began our partnership with DOE we had no sponsors willing to support plant biology and non medical microbiology. For 15 years DOE played a major role in the training of the very best young scientists in these important fields of research simply through its support of LSRF post doctoral fellows. Young scientists interested in

  8. Biosecurity and mastitis in intensive dairy production

    Directory of Open Access Journals (Sweden)

    Boboš Stanko

    2012-01-01

    Full Text Available Newly purchased animals that enter a herd with high milk production can be infected with pathogens of the mammary gland and are a potential risk of infection to the cows on the farm. This risk cannot be avoided entirely, but it can be minimized by taking biosecurity measures that should be written as a policy developed for biosecurity oversight of veterinary service: when older cows are purchased, they should be bought with complete lactations and SCC records, and bacterial examination of milk from the udder quarters must be negative for pathogens of the udder; newly purchased cows should come from herds in which the geometric mean somatic cell count is less than 200,000. The herd must have individual cow SCC recorded at least bimonthly for the previous 6 months; the herd must not have had any history of Strep. agalactiae infection in the last 2 years, the herd should be BVDV-free or vaccinated, and the herd owner must be honest and willing to provide all this information. Our country has accepted the standards for milk quality and hygienic properties that comply with EU standards. The proposed biosafety measures presented in this paper enable the determination of the health status of the herd and the biosecurity level of mastitis in commercial farming in intensive dairy production. [Projekat Ministarstva nauke Republike Srbije, br. TR-31034

  9. FACTORS INFLUENCING BIOSECURITY ADOPTION ON LAYING HEN FARMERS

    Directory of Open Access Journals (Sweden)

    V.S. Lestari

    2014-10-01

    Full Text Available The present study was undertaken to identify factors that influences biosecurity adoption on layinghen farmers in Sidrap district, South Sulawesi. This district was choosen because beside it was famousas the center of laying hen farms, it was also as one of districts in South Sulawesi which suffered fromAvian influenza outbreak. Total samples were 60 respondents. The samples were choosen throughstratified random sampling from two subdistricts which had the most populous of layer smallholders,namely Baranti and Maritengngae. Data were obtained through observations and interviews using aquestionnaire. Data were analyzed using a score based on biosecurity status. Biosecurity status wasobtained based on the adoption of biosecurity measures which consisted of 9 stages: farm inputs, trafficonto farms, distance from sources of pathogens to shed, exposure of farm, biosecurity at farm boundary,biosecurity between farm boundary and shed, biosecurity at the shed door, traffic into the shed andsusceptibility of the flock. Multiple regression model was employed to analyze the data. The studyrevealed that the adoption biosecurity were associated with gender, age, education, farming experience,farm-income, family size and social capital. These variables contributed 20% variation in biosecurityadoption of laying hen farms. However, only farm income, family size and social capital were the majorfactors influencing to the adoption of biosecurity (P<0.05.

  10. Synthetic biology and biosecurity: challenging the ‘myths’

    Directory of Open Access Journals (Sweden)

    Catherine eJefferson

    2014-08-01

    Full Text Available Synthetic biology, a field that aims to ‘make biology easier to engineer’, is routinely described as leading to an increase in the ‘dual use’ threat, i.e. the potential for the same piece of scientific research to be ‘used’ for peaceful purposes or ‘misused’ for warfare or terrorism. Fears have been expressed that the ‘de-skilling’ of biology, combined with online access to the genomic DNA sequences of pathogenic organisms and the reduction in price for DNA synthesis, will make biology increasingly accessible to people operating outside well-equipped professional research laboratories, including people with malevolent intentions. The emergence of DIY biology communities and of the student iGEM competition has come to epitomize this supposed trend towards greater ease of access and the associated potential threat from rogue actors. In this article, we identify 5 ‘myths’ that permeate discussions about synthetic biology and biosecurity, and argue that they embody misleading assumptions about both synthetic biology and bioterrorism. We demonstrate how these myths are challenged by more realistic understandings of the scientific research currently being conducted in both professional and DIY laboratories, and by an analysis of historical cases of bioterrorism. We show that the importance of tacit knowledge is commonly overlooked in the dominant narrative: the focus is on access to biological materials and digital information, rather than on human practices and institutional dimensions. As a result, public discourse on synthetic biology and biosecurity tends to portray speculative scenarios about the future as realities in the present or the near future, when this is not warranted. We suggest that these ‘myths’ play an important role in defining synthetic biology as a ‘promissory’ field of research and as an ‘emerging technology’ in need of governance.

  11. Broken biosecurity? Veterinarians' framing of biosecurity on dairy farms in England.

    Science.gov (United States)

    Shortall, Orla; Ruston, Annmarie; Green, Martin; Brennan, Marnie; Wapenaar, Wendela; Kaler, Jasmeet

    2016-09-15

    There is seen to be a need for better biosecurity - the control of disease spread on and off farm - in the dairy sector. Veterinarians play a key role in communicating and implementing biosecurity measures on farm, and little research has been carried out on how veterinarians see their own and farmers' roles in improving biosecurity. In order to help address this gap, qualitative interviews were carried out with 28 veterinarians from Royal College of Veterinary Surgeon farm accredited practices in England. The results were analysed using a social ecology framework and frame analysis to explore not only what barriers vets identified, but also how vets saw the problem of inadequate biosecurity as being located. Veterinarians' frames of biosecurity were analysed at the individual, interpersonal and contextual scales, following the social ecology framework, which see the problem in different ways with different solutions. Farmers and veterinarians were both framed by veterinarians as individualised groups lacking consistency. This means that best practice is not spread and veterinarians are finding it difficult to work as a group to move towards a "predict and prevent" model of veterinary intervention. But diversity and individualism were also framed as positive and necessary among veterinarians to the extent that they can tailor advice to individual farmers. Veterinarians saw their role in educating the farmer as not only being about giving advice to farmers, but trying to convince the farmer of their perspective and values on disease problems. Vets felt they were meeting with limited success because vets and farmers may be emphasising different framings of biosecurity. Vets emphasise the individual and interpersonal frames that disease problems are a problem on farm that can and should be controlled by individual farmers working with vets. According to vets, farmers may emphasise the contextual frame that biosecurity is largely outside of their control on dairy farms

  12. Broken biosecurity? Veterinarians' framing of biosecurity on dairy farms in England.

    Science.gov (United States)

    Shortall, Orla; Ruston, Annmarie; Green, Martin; Brennan, Marnie; Wapenaar, Wendela; Kaler, Jasmeet

    2016-09-15

    There is seen to be a need for better biosecurity - the control of disease spread on and off farm - in the dairy sector. Veterinarians play a key role in communicating and implementing biosecurity measures on farm, and little research has been carried out on how veterinarians see their own and farmers' roles in improving biosecurity. In order to help address this gap, qualitative interviews were carried out with 28 veterinarians from Royal College of Veterinary Surgeon farm accredited practices in England. The results were analysed using a social ecology framework and frame analysis to explore not only what barriers vets identified, but also how vets saw the problem of inadequate biosecurity as being located. Veterinarians' frames of biosecurity were analysed at the individual, interpersonal and contextual scales, following the social ecology framework, which see the problem in different ways with different solutions. Farmers and veterinarians were both framed by veterinarians as individualised groups lacking consistency. This means that best practice is not spread and veterinarians are finding it difficult to work as a group to move towards a "predict and prevent" model of veterinary intervention. But diversity and individualism were also framed as positive and necessary among veterinarians to the extent that they can tailor advice to individual farmers. Veterinarians saw their role in educating the farmer as not only being about giving advice to farmers, but trying to convince the farmer of their perspective and values on disease problems. Vets felt they were meeting with limited success because vets and farmers may be emphasising different framings of biosecurity. Vets emphasise the individual and interpersonal frames that disease problems are a problem on farm that can and should be controlled by individual farmers working with vets. According to vets, farmers may emphasise the contextual frame that biosecurity is largely outside of their control on dairy farms

  13. Introducing bioinformatics, the biosciences' genomic revolution

    CERN Document Server

    Zanella, Paolo

    1999-01-01

    The general audience for these lectures is mainly physicists, computer scientists, engineers or the general public wanting to know more about what’s going on in the biosciences. What’s bioinformatics and why is all this fuss being made about it ? What’s this revolution triggered by the human genome project ? Are there any results yet ? What are the problems ? What new avenues of research have been opened up ? What about the technology ? These new developments will be compared with what happened at CERN earlier in its evolution, and it is hoped that the similiraties and contrasts will stimulate new curiosity and provoke new thoughts.

  14. Environmental Biosciences Program Fourth Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.d.

    2003-04-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific program, employing a range of research initiatives to identify, study and resolve environmental health risk issues. These initiatives are consistent with the Medical University's role as a comprehensive state-supported health sciences institution and the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable the Medical University to be a national resource for the scientific investigation of environmental health issues. EBP's success in convening worldwide scientific expertise is due in part to the inherent credibility the Medical University brings to the process of addressing these complex issues.

  15. Environmental Biosciences Program Second Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2003-12-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), asbestos and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  16. Environmental Biosciences Quarterly Report, September - December, 2005

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2006-01-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  17. Environmental Biosciences Program Report for Year 2

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2005-10-15

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  18. Environmental Biosciences Program Third Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2003-01-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific program, employing a range of research initiatives to identify, study and resolve environmental health risk issues. These initiatives are consistent with the Medical University's role as a comprehensive state-supported health sciences institution and the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable the Medical University to be a national resource for the scientific investigation of environmental health issues. EBP's success in convening worldwide scientific expertise is due in part to the inherent credibility the Medical University brings to the process of addressing these complex issues.

  19. Environmental Biosciences Program Report for Year Three

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2006-07-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  20. Conference scene: Select Biosciences Epigenetics Europe 2010.

    Science.gov (United States)

    Razvi, Enal S

    2011-02-01

    The field of epigenetics is now on a geometric rise, driven in a large part by the realization that modifiers of chromatin are key regulators of biological processes in vivo. The three major classes of epigenetic effectors are DNA methylation, histone post-translational modifications (such as acetylation, methylation or phosphorylation) and small noncoding RNAs (most notably microRNAs). In this article, I report from Select Biosciences Epigenetics Europe 2010 industry conference held on 14-15 September 2010 at The Burlington Hotel, Dublin, Ireland. This industry conference was extremely well attended with a global pool of delegates representing the academic research community, biotechnology companies and pharmaceutical companies, as well as the technology/tool developers. This conference represented the current state of the epigenetics community with cancer/oncology as a key driver. In fact, it has been estimated that approximately 45% of epigenetic researchers today identify cancer/oncology as their main area of focus vis-à-vis their epigenetic research efforts. PMID:22126149

  1. Environmental Biosciences Program Fourth Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2004-06-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), asbestos and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  2. Environmental Biosciences Program Third Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2004-03-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), asbestos and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  3. Second Quarter Report Environmental Biosciences Program

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2002-10-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific program, employing a range of research initiatives to identify, study and resolve environmental health risk issues. These initiatives are consistent with the Medical University's role as a comprehensive state-supported health sciences institution and the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable the Medical University to be a national resource for the scientific investigation of environmental health issues. EBP's success in convening worldwide scientific expertise is due in part to the inherent credibility the Medical University brings to the process of addressing these complex issues.

  4. Maximum Credible Event Analysis Methods-Tools and Applications in Biosecurity Programs

    International Nuclear Information System (INIS)

    Maximum Credible Event (MCE) analyses are analogous to worst-case scenarios involving a likely mishap scenario in biotechnology bioprocessing operations, biological products testing laboratories, and biological specimen repository facilities, leading to release of particulate/aerosolized etiologic agents into the environment. The purpose of MCE analyses is to estimate the effectiveness of existing safeguards such as the engineering controls, administrative procedures and the attributes of facility design that, in combination, prevent the probability of release of potentially pathogenic or toxic material from the test facility to external environment. As part of our support to the United States Chemical Biological Defense Program, we have developed a unique set og realistic MCE worst-case scenarios for all laboratory and industrial aspects of a biological product development process. Although MCE analysis is a part of an overall facility biosafety assessment, our approach considered biosecurity related issues such as facility vulnerability, employment procedures and workers background investigations, exercise and drills involving local law enforcement and emergency response community, records and audits process, and facility biosafety and biosecurity oversight and governance issues. our standard operating procedure for tracking biological material transfer agreements and operating procedures for materials transfer, together with an integrated checklist of biosafety/biosecurity facility inspection and evaluation was to ensure compliance with all biosafety and biosecurity guidelines.The results of MCE analysis, described in terms of potential hazard of exposure for workers and immediate environment to etiologic agents from the manufacturing process, is a quasi-quantitative estimate of the nature and extent of adverse impact on the health and immediate environment at the vicinity. Etiologic agent exposure concentrations are estimated based on a Gaussian air depression

  5. Lessons on Ethical Decision Making from the Bioscience Industry

    OpenAIRE

    Novas, Carlos

    2006-01-01

    Novas discusses the implications of a new study in PLoS Medicine, in which executives and senior managers from bioscience firms were asked what their companies were doing to promote ethical behaviour.

  6. Public perceptions and preferences for environmental biosecurity in Southeast Queensland

    OpenAIRE

    Sonia Akter; Tom Kompas; Michael Ward

    2011-01-01

    The aim of the study was to understand public understanding of biosecurity and provide an estimate of the non-consumptive use and non-use benefits to be derived from enhanced biosecurity measures in the Southeast Queensland region. A public survey was conducted there during January 2011 using the choice experiment (CE) technique of nonmarket environmental valuation where 400 households were interviewed using fully structured survey questionnaire. Apart from increased household expenditure, th...

  7. Introducing Advances in Bioscience and Clinical Medicine (ABCmed)

    OpenAIRE

    Samad EJ Golzari; Kamyar Ghabili

    2013-01-01

    We are pleased to announce the launch of the Advances in Bioscience and Clinical Medicine (ABCmed), aninternational open-access, and peer-reviewed journal. Mostly intended to cover all areas of bioscience and medicine, theJournal would provide a unique venue for the scientists from all over the world to publish their scientific works. One ofthe advantages of publishing with us is the rapid yet rigorous review process which is mostly performed by ourdistinguished Editorial and Review Board mem...

  8. Environmental Biosciences Program Fourth Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2005-06-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation s need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyles (PCBs), and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this cooperative agreement can be forwarded to Dr. Lawrence C. Mohr in the EBP office of the Medical University of South Carolina at (843) 792-1532.

  9. Environmental Biosciences Program Second Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2004-12-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this cooperative agreement can be forwarded to Dr. Lawrence C. Mohr in the EBP office of the Medical University of South Carolina at (843) 792-1532.

  10. Environmental Biosciences Program Report for Year 3

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2007-04-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the DOE. Plans for restructuring the performance schedule of the trichloroethylene projects have been submitted to the department. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this

  11. Environmental Biosciences Report for Year 3

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2007-10-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the DOE. Plans for restructuring the performance schedule of the trichloroethylene projects have been submitted to the department. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk based decision-making. Questions, comments or requests for further information concerning the activities under this

  12. Biosecurity in public and private office.

    Science.gov (United States)

    Garbin, Artênio José Isper; Garbin, Cléa Adas Saliba; Arcieri, Renato Moreira; Crossato, Michel; Ferreira, Nelly Foster

    2005-06-01

    Biosecurity is currently a concern for all health-related services, including dentistry, since infection control has a relevant importance. In dental practice, health-related occupations have contact with a great number of individuals who are potentially capable to transmit pathogens. This study comprised a descriptive evaluation of the universal precaution measures for infection control adopted by dental practitioners working at public and private offices in the city of Araçatuba, SP. Data collection was performed by a quiz with questions about individual and collective protection equipments. The results showed that the use of caps was reported by 55% of the professionals working at the public sector and 90% for the private sector. The use of masks and gloves was reported by all professionals surveyed; nevertheless, glove change between patients was not reported by 40% of professionals working at the public sector. There were more flaws in public offices as to the use of protective barriers, since except for the use of gloves, gowns and masks, the frequency of use of those barriers was smaller than at private offices.

  13. Teaching and learning about bioscience ethics with undergraduates.

    Science.gov (United States)

    Van Rooy, Wilhelmina; Pollard, Irina

    2002-01-01

    Bioscience ethics acts as a practical interface between science and bioethics. It links scientific endeavour and its application into adaptive forms of bioethical consensus. Its major elements are increased understanding of biological systems, responsible use of technology, and curtailment of ethnocentric debates in tune with new scientific insights. This paper briefly describes the students' learning experience gained from the vacation unit BIOL 240, Introduction to Bioscience Ethics, as taught in biology, Macquarie University. On the basis of our evidence students were overwhelmingly positive about their learning because the unit assisted them to better face dilemmas that arise from the application of science and technology. The structure also provided active engagement with the subject matter and preferred learning environments that supported and contested their understanding of concepts relevant to bioscience and bioethics. PMID:14741947

  14. Bio-Security Proficiencies Project for Beginning Producers in 4-H

    Science.gov (United States)

    Smith, Martin H.; Meehan, Cheryl L.; Borba, John A.

    2014-01-01

    Improving bio-security practices among 4-H members who raise and show project animals is important. Bio-security measures can reduce the risk of disease spread and mitigate potential health and economic risks of disease outbreaks involving animal and zoonotic pathogens. Survey data provided statistical evidence that the Bio-Security Proficiencies…

  15. Measuring The Cost of Biosecurity at Broiler Farms

    OpenAIRE

    Sri Lestari, Veronica

    2013-01-01

    This research was conducted to know the ratio between investment and business scale in an effort to determine whether large-scale farms or small-scale farms invest more in biosecurity. Based on the results of this study, it can be concluded that the average cost of biosecurity for large and small scale broiler farm was IDR 310.7/bird and IDR 1,340/bird respectively. The higher the number of birds, the lower the cost per bird. Future work will include more variables in the economic analysis...

  16. 76 FR 24501 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2011-05-02

    ...-202-2783, (Formerly: Forensic Toxicology Laboratory Baptist Medical Center) Clinical Reference Lab...Kline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories) Quest Diagnostics Incorporated... Clinical Laboratories; SmithKline Bio-Science Laboratories) Quest Diagnostics Incorporated, 8401...

  17. 77 FR 60449 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2012-10-03

    ... Laboratory Baptist Medical Center). Clinical Reference Lab, 8433 Quivira Road, Lenexa, KS 66215-2802, 800-445...Kline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories). Quest Diagnostics... Clinical Laboratories; SmithKline Bio-Science Laboratories). Quest Diagnostics Incorporated, 8401...

  18. 78 FR 19500 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2013-04-01

    ...-202-2783, (Formerly: Forensic Toxicology Laboratory Baptist Medical Center) Clinical Reference Lab...Kline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories) Quest Diagnostics Incorporated... Clinical Laboratories; SmithKline Bio-Science Laboratories) Quest Diagnostics Incorporated, 8401...

  19. 77 FR 5037 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2012-02-01

    ..., (Formerly: Forensic Toxicology Laboratory Baptist Medical Center); Clinical Reference Lab, 8433 Quivira Road..., 800-729-6432, (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories..., (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories); Quest...

  20. 78 FR 59946 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2013-09-30

    ...). Clinical Reference Lab, 8433 Quivira Road, Lenexa, KS 66215-2802, 800- 445-6917. Doctors Laboratory, Inc..., 800-729-6432, (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories..., (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories). Quest...

  1. 77 FR 69642 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2012-11-20

    ... Laboratory Baptist Medical Center.) Clinical Reference Lab, 8433 Quivira Road, Lenexa, KS 66215-2802, 800-445...: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories.) Quest Diagnostics... Clinical Laboratories; SmithKline Bio-Science Laboratories.) Quest Diagnostics Incorporated, 8401...

  2. 76 FR 6147 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2011-02-03

    ...-202-2783. (Formerly: Forensic Toxicology Laboratory Baptist Medical Center.) Clinical Reference Lab.... (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories.) Quest Diagnostics... Clinical Laboratories; SmithKline Bio-Science Laboratories.) Quest Diagnostics Incorporated, 8401...

  3. 78 FR 66034 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2013-11-04

    ...) Clinical Reference Lab, 8433 Quivira Road, Lenexa, KS 66215-2802, 800- 445-6917 Doctors Laboratory, Inc..., 800-729-6432, (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories..., (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories) Quest...

  4. 77 FR 12862 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2012-03-02

    ... Laboratory Baptist Medical Center). Clinical Reference Lab, 8433 Quivira Road, Lenexa, KS 66215-2802, 800..., (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories). Quest Diagnostics... Clinical Laboratories; SmithKline Bio-Science Laboratories). Quest Diagnostics Incorporated, 8401...

  5. 78 FR 54903 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2013-09-06

    ...). Clinical Reference Lab, 8433 Quivira Road, Lenexa, KS 66215-2802, 800- 445-6917. Doctors Laboratory, Inc..., 800-729-6432 (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories... (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories). Quest...

  6. 77 FR 54597 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2012-09-05

    ... Laboratory Baptist Medical Center). Clinical Reference Lab, 8433 Quivira Road, Lenexa, KS 66215-2802, 800...Kline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories). Quest Diagnostics... Clinical Laboratories; SmithKline Bio-Science Laboratories). Quest Diagnostics Incorporated, 8401...

  7. Teaching Critical Appraisal to Sport & Exercise Sciences and Biosciences Students

    Science.gov (United States)

    Phillips, Anna C.

    2009-01-01

    Seminars were implemented to develop undergraduates' critical appraisal skills and their effectiveness was evaluated. Participants were 140 undergraduate students consisting of 103 students from Sport and Exercise Sciences and 37 from Biosciences. Four seminars were employed to develop and reinforce critical thinking and provide an opportunity for…

  8. Integrating anticipated nutrigenomics bioscience applications with ethical aspects

    NARCIS (Netherlands)

    Levesque, L.; Ozdemir, V.; Gremmen, B.; Godard, B.

    2008-01-01

    Nutrigenomics is a subspecialty of nutrition science which aims to understand how gene-diet interactions influence individuals' response to food, disease susceptibility, and population health. Yet ethical enquiry into this field is being outpaced by nutrigenomics bioscience. The ethical issues surro

  9. Challenges in Understanding Photosynthesis in a University Introductory Biosciences Class

    Science.gov (United States)

    Södervik, Ilona; Virtanen, Viivi; Mikkilä-Erdmann, Mirjamaija

    2015-01-01

    University students' understanding of photosynthesis was examined in a large introductory biosciences class. The focus of this study was to first examine the conceptions of photosynthesis among students in class and then to investigate how a certain type of text could enhance students' understanding of photosynthesis. The study was based on pre-…

  10. 76 FR 161 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2011-01-03

    ...-202-2783. (Formerly: Forensic Toxicology Laboratory Baptist Medical Center.) Clinical Reference Lab..., GA 30084. 800-729-6432.(Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science.... (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories.) Quest...

  11. 78 FR 72684 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2013-12-03

    ... Baptist Medical Center) Clinical Reference Lab, 8433 Quivira Road, Lenexa, KS 66215-2802, 800- 445-6917..., 800-729-6432, (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories..., (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories) Quest...

  12. 78 FR 7795 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2013-02-04

    ... Baptist Medical Center) Clinical Reference Lab, 8433 Quivira Road, Lenexa, KS 66215-2802, 800- 445-6917..., 800-729-6432, (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories..., (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories) ]...

  13. 76 FR 46309 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2011-08-02

    ...-202-2783 (Formerly: Forensic Toxicology Laboratory Baptist Medical Center) Clinical Reference Lab..., GA 30084, 800-729-6432 (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science... (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories) Quest...

  14. 78 FR 314 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2013-01-03

    ... Baptist Medical Center) ] Clinical Reference Lab, 8433 Quivira Road, Lenexa, KS 66215-2802, 800- 445-6917..., 800-729-6432, (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories..., (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories) Quest...

  15. 78 FR 14100 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2013-03-04

    ... Laboratory Baptist Medical Center) Clinical Reference Lab, 8433 Quivira Road, Lenexa, KS 66215-2802, 800- 445..., GA 30084, 800-729-6432 (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science... (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories) Quest...

  16. 76 FR 40924 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2011-07-12

    ...-202-2783 (Formerly: Forensic Toxicology Laboratory Baptist Medical Center). Clinical Reference Lab..., GA 30084, 800-729-6432 (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science... (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories). Quest...

  17. 76 FR 61110 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2011-10-03

    ...-202-2783. (Formerly: Forensic Toxicology Laboratory Baptist Medical Center.) Clinical Reference Lab..., GA 30084, 800-729-6432. (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science.... (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories.) Quest...

  18. 78 FR 46996 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2013-08-02

    ... Baptist Medical Center) Clinical Reference Lab, 8433 Quivira Road, Lenexa, KS 66215-2802, 800- 445-6917..., (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories) Quest Diagnostics... Clinical Laboratories; SmithKline Bio-Science Laboratories) Quest Diagnostics Incorporated, 8401...

  19. Assessment of collaboration and interoperability in an information management system to support bioscience research.

    Science.gov (United States)

    Myneni, Sahiti; Patel, Vimla L

    2009-01-01

    Biomedical researchers often have to work on massive, detailed, and heterogeneous datasets that raise new challenges of information management. This study reports an investigation into the nature of the problems faced by the researchers in two bioscience test laboratories when dealing with their data management applications. Data were collected using ethnographic observations, questionnaires, and semi-structured interviews. The major problems identified in working with these systems were related to data organization, publications, and collaboration. The interoperability standards were analyzed using a C(4)I framework at the level of connection, communication, consolidation, and collaboration. Such an analysis was found to be useful in judging the capabilities of data management systems at different levels of technological competency. While collaboration and system interoperability are the "must have" attributes of these biomedical scientific laboratory information management applications, usability and human interoperability are the other design concerns that must also be addressed for easy use and implementation. PMID:20351900

  20. Assessment of Collaboration and Interoperability in an Information Management System to Support Bioscience Research

    Science.gov (United States)

    Myneni, Sahiti; Patel, Vimla L.

    2009-01-01

    Biomedical researchers often have to work on massive, detailed, and heterogeneous datasets that raise new challenges of information management. This study reports an investigation into the nature of the problems faced by the researchers in two bioscience test laboratories when dealing with their data management applications. Data were collected using ethnographic observations, questionnaires, and semi-structured interviews. The major problems identified in working with these systems were related to data organization, publications, and collaboration. The interoperability standards were analyzed using a C4I framework at the level of connection, communication, consolidation, and collaboration. Such an analysis was found to be useful in judging the capabilities of data management systems at different levels of technological competency. While collaboration and system interoperability are the “must have” attributes of these biomedical scientific laboratory information management applications, usability and human interoperability are the other design concerns that must also be addressed for easy use and implementation. PMID:20351900

  1. Assessment of collaboration and interoperability in an information management system to support bioscience research.

    Science.gov (United States)

    Myneni, Sahiti; Patel, Vimla L

    2009-11-14

    Biomedical researchers often have to work on massive, detailed, and heterogeneous datasets that raise new challenges of information management. This study reports an investigation into the nature of the problems faced by the researchers in two bioscience test laboratories when dealing with their data management applications. Data were collected using ethnographic observations, questionnaires, and semi-structured interviews. The major problems identified in working with these systems were related to data organization, publications, and collaboration. The interoperability standards were analyzed using a C(4)I framework at the level of connection, communication, consolidation, and collaboration. Such an analysis was found to be useful in judging the capabilities of data management systems at different levels of technological competency. While collaboration and system interoperability are the "must have" attributes of these biomedical scientific laboratory information management applications, usability and human interoperability are the other design concerns that must also be addressed for easy use and implementation.

  2. Dispatches from the Interface of Salivary Bioscience and Neonatal Research

    OpenAIRE

    KristinVoegtline; DouglasA.Granger

    2014-01-01

    The emergence of the interdisciplinary field of salivary bioscience has created opportunity for neonatal researchers to measure multiple components of biological systems non-invasively in oral fluids. The implications are profound and potentially high impact. From a single oral fluid specimen, information can be obtained about a vast array of biological systems (e.g., endocrine, immune, autonomic nervous system) and the genetic polymorphisms related to individual differences in their function...

  3. Bioscience methodologies in physical chemistry an engineering and molecular approach

    CERN Document Server

    D'Amore, Alberto

    2013-01-01

    The field of bioscience methodologies in physical chemistry stands at the intersection of the power and generality of classical and quantum physics with the minute molecular complexity of chemistry and biology. This book provides an application of physical principles in explaining and rationalizing chemical and biological phenomena. It does not stick to the classical topics that are conventionally considered as part of physical chemistry; instead it presents principles deciphered from a modern point of view, which is the strength of this book.

  4. Fluorescence lifetime imaging in biosciences: technologies and applications

    Institute of Scientific and Technical Information of China (English)

    Raluca NIESNER; Karl-Heinz GERICKE

    2008-01-01

    The biosciences require the development of methods that allow a non-invasive and rapid investigation of biological systems. In this aspect, high-end imaging tech-niques allow intravital microscopy in real-time, providing information on a molecular basis. Far-field fluorescence imaging techniques are some of the most adequate methods for such investigations. However, there are great differences between the common fluorescence imaging techniques, i.e., wide-field, confocal one-photon and two-photon microscopy, as far as their applicability in diverse bioscientific research areas is concerned. In the first part of this work, we briefly compare these techniques. Standard methods used in the biosciences, i.e., steady-state techniques based on the analy-sis of the total fluorescence signal originating from the sam-ple, can successfully be employed in the study of cell, tissue and organ morphology as well as in monitoring the macro-scopic tissue function. However, they are mostly inadequate for the quantitative investigation of the cellular function at the molecular level. The intrinsic disadvantages of steady-state techniques are countered by using time-resolved tech-niques. Among these fluorescence lifetime imaging (FLIM) is currently the most common. Different FLIM principles as well as applications of particular relevance for the biosci-ences, especially for fast intravital studies are discussed in this work.

  5. Trypanosomes of Australian Mammals: Knowledge Gaps Regarding Transmission and Biosecurity.

    Science.gov (United States)

    Thompson, Craig K; Thompson, R C Andrew

    2015-11-01

    Trypanosomes infect humans, domestic animals, and wildlife, and are transmitted by haematophagous invertebrate vectors. Eight native trypanosome species have been described from Australian indigenous mammals, along with other unnamed isolates and genotypes. Associated difficulties relating to the confirmation of cyclical and mechanical vector candidates has hindered vector identification in Australia, with no successful experimental transmission documented for any of these native trypanosomes to indigenous mammals. We discuss pending biosecurity issues, with significant importance placed on the close phylogenetic and phenotypic relationship shared between Trypanosoma cruzi and some Australian trypanosomes. With such a dearth of information, we highlight the importance of keeping an open mind, which considers all possibilities during future investigations of vectors and their associated biosecurity issues in Australia.

  6. MPACT OF GENETIC BIOTECHNOLOGIES ON BIOSECURITY AND FOOD SAFETY

    Directory of Open Access Journals (Sweden)

    NICA-BADEA DELIA

    2014-05-01

    Full Text Available Biosecurity is a relatively new area global, being promoted by the significant results, particularly in the last 20 years, fundamental and applied research. Biotechnology is a collection of techniques that can be used in the agro-food, medical and industrial. The paper examines the potential impact of transgenic biotechnology, vulnerabilities, implications, benefits and risks, quality of life and health. Introduction into the environment, cross-border trade and use of GMOs resulting from modern biotechnology can untoward effects on the conservation and sustainable use of biological diversity, food security and safety. It is openly acknowledged that modern biotechnology has great potential to promote human welfare, in particular, to overcome the critical needs in food, agriculture and human health. Establish appropriate safety measures when using genetically modified organisms (biosecurity policy, regulatory regime, scientific and technical measures is a highly sensitive process, aiming both to maximize the benefits of modern biotechnology and to minimize potential risk

  7. IMPACT OF GENETIC BIOTECHNOLOGIES ON BIOSECURITY AND FOOD SAFETY

    OpenAIRE

    NICA-BADEA DELIA

    2014-01-01

    Biosecurity is a relatively new area global, being promoted by the significant results, particularly in the last 20 years, fundamental and applied research. Biotechnology is a collection of techniques that can be used in the agro-food, medical and industrial. The paper examines the potential impact of transgenic biotechnology, vulnerabilities, implications, benefits and risks, quality of life and health. Introduction into the environment, crossborder trade and use of GMOs resulting from moder...

  8. MPACT OF GENETIC BIOTECHNOLOGIES ON BIOSECURITY AND FOOD SAFETY

    OpenAIRE

    NICA-BADEA DELIA

    2014-01-01

    Biosecurity is a relatively new area global, being promoted by the significant results, particularly in the last 20 years, fundamental and applied research. Biotechnology is a collection of techniques that can be used in the agro-food, medical and industrial. The paper examines the potential impact of transgenic biotechnology, vulnerabilities, implications, benefits and risks, quality of life and health. Introduction into the environment, cross-border trade and use of GMOs resulti...

  9. Criminal Genomic Pragmatism: Prisoners' Representations of DNA Technology and Biosecurity

    Directory of Open Access Journals (Sweden)

    Helena Machado

    2012-01-01

    Full Text Available Background. Within the context of the use of DNA technology in crime investigation, biosecurity is perceived by different stakeholders according to their particular rationalities and interests. Very little is known about prisoners’ perceptions and assessments of the uses of DNA technology in solving crime. Aim. To propose a conceptual model that serves to analyse and interpret prisoners’ representations of DNA technology and biosecurity. Methods. A qualitative study using an interpretative approach based on 31 semi-structured tape-recorded interviews was carried out between May and September 2009, involving male inmates in three prisons located in the north of Portugal. The content analysis focused on the following topics: the meanings attributed to DNA and assessments of the risks and benefits of the uses of DNA technology and databasing in forensic applications. Results. DNA was described as a record of identity, an exceptional material, and a powerful biometric identifier. The interviewees believed that DNA can be planted to incriminate suspects. Convicted offenders argued for the need to extend the criteria for the inclusion of DNA profiles in forensic databases and to restrict the removal of profiles. Conclusions. The conceptual model entitled criminal genomic pragmatism allows for an understanding of the views of prison inmates regarding DNA technology and biosecurity.

  10. Biosecurity on Finnish cattle, pig and sheep farms - results from a questionnaire.

    Science.gov (United States)

    Sahlström, Leena; Virtanen, Terhi; Kyyrö, Jonna; Lyytikäinen, Tapani

    2014-11-01

    Biosecurity is important in order to prevent disease transmission between animals on farms as well as from farm to farm. Personal biosecurity routines such as hand washing and the use of protective clothing and footwear are measures that should be used at all farms. Other measures are for example related to purchasing new animals to the farm. A questionnaire-based survey was undertaken to study the frequency of use of different biosecurity measures on cattle, pig and sheep farms in Finland. Information about which biosecurity measures are in use is needed for contingency planning of emerging diseases or when combating endemic diseases. Knowledge about the level of biosecurity of a farm is also needed in order to assess if and where improvement is needed. Information regarding biosecurity levels may benefit future animal disease risk assessments. A total of 2242 farmers responded to the questionnaire resulting in a response rate of 45%. The implementation frequencies of different biosecurity measures are reported. The results revealed differences between species: large pig farms had a better biosecurity level than small cattle farms. There were also differences between production types such as dairy farming versus beef cattle farming, but these were not as remarkable. Sheep farming in Finland is sparse and the large number of hobby farmers keeps the biosecurity level low on sheep farms. This might represent a risk for the entire sheep farming industry. The Finnish farmers were satisfied with their on-farm biosecurity. Eighty percent of the farmers report that they were satisfied even though the biosecurity level was not particularly high. The implementation of biosecurity measures could be further improved. Even though the disease situation in Finland is good today, one must be prepared for possible epidemics of threatening diseases. PMID:25147126

  11. 77 FR 32653 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2012-06-01

    ... Baptist Medical Center). Clinical Reference Lab, 8433 Quivira Road, Lenexa, KS 66215-2802, 800- 445-6917... 30084, 800-729-6432, (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science..., (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science Laboratories). Quest...

  12. SBBN 2010: 7. Congress of the Brazilian Society of Nuclear Biosciences. Radiations in biosciences: advances and trends

    International Nuclear Information System (INIS)

    Advance and new perspectives related to the use of ionizing and no ionizing radiations in nuclear biosciences are presented. Multidisciplinary approach, including radiopharmacy, radioprotection and dosimetry, cytogenetic, biosafety, radioecology, environmental toxicology are studied. Topics of Nuclear medicine, radiotherapy and image diagnosis, such as computerized tomography, PET scan, phantoms, biomedical radiography, are reported. Use of radioisotopes, evaluation of radiation dose rates, radiation dose distribution, radiation monitoring is considered. Environmental impact of radiation are also in human beings, animals and for several purposes are analyzed. (MAC)

  13. Determinants of biosecurity behaviour of British cattle and sheep farmers-a behavioural economics analysis.

    Science.gov (United States)

    Toma, Luiza; Stott, Alistair W; Heffernan, Claire; Ringrose, Siân; Gunn, George J

    2013-03-01

    The paper analyses the impact of a priori determinants of biosecurity behaviour of farmers in Great Britain. We use a dataset collected through a stratified telephone survey of 900 cattle and sheep farmers in Great Britain (400 in England and a further 250 in Wales and Scotland respectively) which took place between 25 March 2010 and 18 June 2010. The survey was stratified by farm type, farm size and region. To test the influence of a priori determinants on biosecurity behaviour we used a behavioural economics method, structural equation modelling (SEM) with observed and latent variables. SEM is a statistical technique for testing and estimating causal relationships amongst variables, some of which may be latent using a combination of statistical data and qualitative causal assumptions. Thirteen latent variables were identified and extracted, expressing the behaviour and the underlying determining factors. The variables were: experience, economic factors, organic certification of farm, membership in a cattle/sheep health scheme, perceived usefulness of biosecurity information sources, knowledge about biosecurity measures, perceived importance of specific biosecurity strategies, perceived effect (on farm business in the past five years) of welfare/health regulation, perceived effect of severe outbreaks of animal diseases, attitudes towards livestock biosecurity, attitudes towards animal welfare, influence on decision to apply biosecurity measures and biosecurity behaviour. The SEM model applied on the Great Britain sample has an adequate fit according to the measures of absolute, incremental and parsimonious fit. The results suggest that farmers' perceived importance of specific biosecurity strategies, organic certification of farm, knowledge about biosecurity measures, attitudes towards animal welfare, perceived usefulness of biosecurity information sources, perceived effect on business during the past five years of severe outbreaks of animal diseases, membership

  14. Call for Papers-Bioscience Methods(ISSN 1925-1920)

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Bioscience Methods (BM) (ISSN 1925-1920) is a new launched, open access and peer-reviewed journal that dedicates to publish the original research papers involving in innovative technologies and novel experimental arts within the fields of biosciences.

  15. Students Turned Off by Turnitin? Perception of Plagiarism and Collusion by Undergraduate Bioscience Students

    Science.gov (United States)

    Thompsett, Andrew; Ahluwalia, Jatinder

    2010-01-01

    Research on undergraduate bioscience students and the incidence of plagiarism is still in its infancy and a key problem arises in gauging the perception of undergraduate students on plagiarism and collusion in biosciences subjects because of the lack of empirical data. The aim of this study was to provide qualitative data on the perceptions of…

  16. The biosecurity of on-farm mortality composting.

    Science.gov (United States)

    Wilkinson, K G

    2007-03-01

    Composting is a natural biological decomposition process that takes place under aerobic and thermophilic conditions. It can be used for the day-to-day management of mortalities on farms and for carcass disposal in emergency animal disease (EAD) outbreaks. In mortality composting, carcasses are placed in piles or bins together with supplemental carbon sources such as sawdust, litter, straw or wood shavings. Composting is particularly suitable for broiler-farm mortalities and litter. In the case of emergency disease outbreaks, composting can be conducted either inside or outside the poultry house following killing. Composting has been successfully employed for emergency disposal of carcasses in a few cases in North America, but research is lacking on the biosecurity of the process. Composting is a well-established pathogen reduction technology, but process management and heterogenous pile conditions pose particular challenges for validating the microbiological safety of mortality composting. This paper reviews the available information on the biosecurity of mortality composting, identifies potential sources of risk, and highlights emerging research needs. Reports to date of the use of composting in EAD outbreaks are also discussed.

  17. Negative impact of laws regarding biosecurity and bioterrorism on real diseases.

    Science.gov (United States)

    Wurtz, N; Grobusch, M P; Raoult, D

    2014-06-01

    Research on highly pathogenic microorganisms in biosafety level 3 and 4 laboratories is very important for human public health, as it provides opportunities for the development of vaccines and novel therapeutics as well as diagnostic methods to prevent epidemics. However, in recent years, after the anthrax and World Trade Center attacks in 2001 in the USA, the threat of bioterrorism has grown for both the public and the authorities. As a result, technical and physical containment measures and biosafety and biosecurity practices have been implemented in laboratories handling these dangerous pathogens. Working with selected biological agents and toxins is now highly regulated, owing to their potential to pose a threat to public health and safety, despite the fact that the anthrax attack was found to be the result of a lack of security at a US Army laboratory. Thus, these added regulations have been associated with a large amount of fruitless investment. Herein, we describe the limitations of research in these facilities, and the multiple consequences of the increased regulations. These limitations have seriously negatively impacted on the number of collaborations, the size of research projects, and, more generally, scientific research on microbial pathogens. Clearly, the actual number of known victims and fatalities caused by the intentional use of microorganisms has been negligible as compared with those caused by naturally acquired human infections.

  18. Division of Agro technology and Biosciences: Past, Present and Future

    International Nuclear Information System (INIS)

    In presenter speech, he outlined several topics regarding development of Agro technology and Biosciences Division from 31 years ago. This division started with Unit Sains Hidupan Liar under PUSPATI in 1981 and change their names to Program Isotop dan Sinaran dalam Biologi dan Pertanian under Nuclear Technology Unit (UTN) (1983). In 1990 their premise change to MINT-Tech Park. This program responsible for conducting research in agro technology using nuclear technology. Several achievements achieved by this division since established. They also succeed in mutating banana namely Novaria banana (1994), Tongkat Ali rice (1990), ground nut (2003), orchids, organic fertilizer and foliage in 2000. The vision of this division are to promote and enhance innovation and applications in nuclear technology to achieve security in food productivity, safety and quality and ecological awareness for economics competitiveness and vibrancy in agrobioindustry and community development. (author)

  19. Applications of computational tools in biosciences and medical engineering

    CERN Document Server

    Altenbach, Holm

    2015-01-01

     This book presents the latest developments and applications of computational tools related to the biosciences and medical engineering. It also reports the findings of different multi-disciplinary research projects, for example, from the areas of scaffolds and synthetic bones, implants and medical devices, and medical materials. It is also shown that the application of computational tools often requires mathematical and experimental methods. Computational tools such as the finite element methods, computer-aided design and optimization as well as visualization techniques such as computed axial tomography open up completely new research fields that combine the fields of engineering and bio/medical. Nevertheless, there are still hurdles since both directions are based on quite different ways of education. Often even the “language” can vary from discipline to discipline.

  20. Introducing Advances in Bioscience and Clinical Medicine (ABCmed

    Directory of Open Access Journals (Sweden)

    Samad EJ Golzari

    2013-07-01

    Full Text Available We are pleased to announce the launch of the Advances in Bioscience and Clinical Medicine (ABCmed, aninternational open-access, and peer-reviewed journal. Mostly intended to cover all areas of bioscience and medicine, theJournal would provide a unique venue for the scientists from all over the world to publish their scientific works. One ofthe advantages of publishing with us is the rapid yet rigorous review process which is mostly performed by ourdistinguished Editorial and Review Board members; this obviously hard-to-achieve goal would not be realized withouttheir continuous support and advice.Another distinguishing characteristic of ABCmed is the diversity of published items in each issue. The editorial team ofthe Journal has devoted separate sections to rather unknown yet interesting fields of the science for instance hypotheses,history of medicine, etc. In the first issue of ABCmed, the readers might refer to the two published hypotheseshighlighting the possible role of chamomile in the treatment of rheumatoid arthritis, and also the preventive effects oftadalafil together with nimodipine in subarachnoid hemorrhage-induced cerebral vasospasm.Letters to the Editor are one of the major sectors in the ABCmed providing not only further on the already publisheddata in the Journal, but also personal comments on the major public health concerns and medical issues. In the firstissue of the Journal, a very important cancer surgery complication is debated, introducing different strategies in the painmanagement of breast cancer patients.We hope that ABCmed will provide a basis to bring together the scientists from all over the globe with the same goal ofpromoting science.

  1. Mini-review: Assessing the drivers of ship biofouling management--aligning industry and biosecurity goals.

    Science.gov (United States)

    Davidson, Ian; Scianni, Christopher; Hewitt, Chad; Everett, Richard; Holm, Eric; Tamburri, Mario; Ruiz, Gregory

    2016-01-01

    Biofouling exerts a frictional and cost penalty on ships and is a direct cause of invasion by marine species. These negative consequences provide a unifying purpose for the maritime industry and biosecurity managers to prevent biofouling accumulation and transfer, but important gaps exist between these sectors. This mini-review examines the approach to assessments of ship biofouling among sectors (industry, biosecurity and marine science) and the implications for existing and emerging management of biofouling. The primary distinctions between industry and biosecurity in assessment of vessels biofouling revolve around the resolution of biological information collected and the specific wetted surface areas of primary concern to each sector. The morphological characteristics of biofouling and their effects on propulsion dynamics are of primary concern to industry, with an almost exclusive focus on the vertical sides and flat bottom of hulls and an emphasis on antifouling and operational performance. In contrast, the identity, biogeography, and ecology of translocated organisms is of highest concern to invasion researchers and biosecurity managers and policymakers, especially as it relates to species with known histories of invasion elsewhere. Current management practices often provide adequate, although not complete, provision for hull surfaces, but niche areas are well known to enhance biosecurity risk. As regulations to prevent invasions emerge in this arena, there is a growing opportunity for industry, biosecurity and academic stakeholders to collaborate and harmonize efforts to assess and manage biofouling of ships that should lead to more comprehensive biofouling solutions that promote industry goals while reducing biosecurity risk and greenhouse gas emissions.

  2. Horse owners' biosecurity practices following the first equine influenza outbreak in Australia.

    Science.gov (United States)

    Schemann, K; Taylor, M R; Toribio, J-A L M L; Dhand, N K

    2011-12-15

    A cross-sectional study was conducted involving 759 Australian horse owners to determine their biosecurity practices and perceptions one year after the 2007 equine influenza outbreak and to investigate the factors influencing these perceptions and practices. A web link to an online questionnaire was sent to 1224 horse owners as a follow-up to a previous study to obtain information about biosecurity perceptions and practices, impacts of the 2007 EI outbreak, demographic information and information about horse industry involvement. Ordinal logistic regression analyses were conducted to determine factors associated with poor biosecurity practices. Biosecurity compliance (low, medium, high), as determined by horse owners' responses to a 16-item question on the frequency of various biosecurity measures, was used as the outcome variable in ordinal logistic regression analyses. Variables with a univariable p-value ≤0.2 were eligible for inclusion in multivariable models built using a manual stepwise approach. Variables with a p-value models were retained in the final model. Two potential confounders - age and gender of participants - were included in the final model irrespective of their p-values. Thirty percent of the respondents had low biosecurity compliance and were performing biosecurity practices 'not very often' or 'never'. Younger people, people with two or more children, those who were not involved with horses commercially and those who had no long-term business impacts resulting from the 2007 EI outbreak were more likely to have lower biosecurity compliance. People who were not fearful of a future outbreak of equine influenza in Australia and those who thought their current hygiene and access control practices were not very effective in protecting their horses also had poor biosecurity practices. In this observational study we identified factors associated with a group of horse owners with low levels of biosecurity compliance. As this cross-sectional study

  3. Associations between biosecurity and outbreaks of canine distemper on Danish mink farms in 2012–2013

    OpenAIRE

    Gregers-Jensen, Louise; Agger, Jens Frederik; Hammer, Anne Sofie Vedsted; Andresen, Lars; Chriél, Mariann; Hagberg, Emma; Jensen, Mette Kragh; Hansen, Mette Sif; Hjulsager, Charlotte Kristiane; Struve, Tina

    2015-01-01

    Background During 8 months from July 2012 to February 2013, a major outbreak of canine distemper involving 64 mink farms occurred on the Danish peninsula of Jutland. The canine distemper outbreak was associated with exposure of farmed mink to infected wild carnivores and could represent a deficit in biosecurity on the mink farms. The aim of this study was to investigate the extent and association of specific biosecurity measures with the outbreak. The study was carried out in an epidemiologic...

  4. Improving Smallholder Farmer Biosecurity in the Mekong Region Through Change Management.

    Science.gov (United States)

    Young, J R; Evans-Kocinski, S; Bush, R D; Windsor, P A

    2015-10-01

    Transboundary animal diseases including foot-and-mouth disease and haemorrhagic septicaemia remain a major constraint for improving smallholder large ruminant productivity in the Mekong region, producing negative impacts on rural livelihoods and compromising efforts to reduce poverty and food insecurity. The traditional husbandry practices of smallholders largely exclude preventive health measures, increasing risks of disease transmission. Although significant efforts have been made to understand the social aspects of change development in agricultural production, attention to improving the adoption of biosecurity has been limited. This study reviews smallholder biosecurity risk factors identified in the peer-reviewed literature and from field research observations conducted in Cambodia and Laos during 2006-2013, considering these in the context of a change management perspective aimed at improving adoption of biosecurity measures. Motivation for change, resistance to change, knowledge management, cultural dimensions, systems theory and leadership are discussed. Due to geographical, physical and resource variability, the implementation of biosecurity interventions suitable for smallholders is not a 'one size fits all'. Smallholders should be educated in biosecurity principles and empowered to make personal decisions rather than adopt prescribed pre-defined interventions. Biosecurity interventions should be aligned with smallholder farmer motivations, preferably offering clear short-term risk management benefits that elicit interest from smallholders. Linking biosecurity and disease control with improved livestock productivity provides opportunities for sustainable improvements in livelihoods. Participatory research and extension that improves farmer knowledge and practices offers a pathway to elicit sustainable broad-scale social change. However, examples of successes need to be communicated both at the 'evidence-based level' to influence regional policy

  5. Developing and evaluating effective bioscience learning activities for nursing students.

    Science.gov (United States)

    Salvage-Jones, Judith; Hamill, Jessie; Todorovic, Michael; Barton, Matthew J; Johnston, Amy N B

    2016-07-01

    Effective engagement of nursing students in the study of biosciences remains a challenge for many tertiary institutes. In this study we attempted to implement and then evaluate a simple hands-on intervention, consisting of a series of hands-on games and puzzles, to increase nursing student engagement with core concepts and anatomical learning involved in clinical anatomy and physiology. The study used a quazi-experimental longitudinal before and after design, to explore the effect of a learning intervention on student performance. Set across three different campuses of the same University, it included 1320 first year undergraduate nursing students from 2013 to 2014 who were studying Anatomy and Physiology. Students were exposed to the interventions or not, and concomitant academic performance, weekly quiz scores, performance in fortnightly worksheets and, across the semester, exam performance were compared. The results show that while the intervention appeared to increase academic performance in students on one campus (2013) compared to the other two, this difference was not sustained into 2014 when a bigger cohort was examined. Despite significant subjective student satisfaction and enthusiasm about these learning and teaching interventions, the data does not support the capacity of these activities to enhance student academic performance. Tertiary entrance scores, being a non-native English speakers and socio-economic status all had a bigger impact on student performance than engagement with fun anatomy and physiology activities. PMID:27428695

  6. Environmental Biosciences Program Third Quarter Report, Year 2

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2005-03-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  7. Environmental Biosciences Program Quarterly Report for Year 3

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2006-04-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  8. MUSC Environmental Biosciences Program First Quarter Report May - June, 2002

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr

    2002-07-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC02-98CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific program, employing a range of research initiatives to identify, study and resolve environmental health risk issues. These initiatives are consistent with the Medical University's role as a comprehensive state-supported health sciences institution and the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable the Medical University to be a national resource for the scientific investigation of environmental health issues. EBP's success in convening worldwide scientific expertise is due in part to the inherent credibility the Medical University brings to the process of addressing these complex issues.

  9. Code of Conduct on Biosecurity for Biological Resource Centres: procedural implementation.

    Science.gov (United States)

    Rohde, Christine; Smith, David; Martin, Dunja; Fritze, Dagmar; Stalpers, Joost

    2013-07-01

    A globally applicable code of conduct specifically dedicated to biosecurity has been developed together with guidance for its procedural implementation. This is to address the regulations governing potential dual-use of biological materials, associated information and technologies, and reduce the potential for their malicious use. Scientists researching and exchanging micro-organisms have a responsibility to prevent misuse of the inherently dangerous ones, that is, those possessing characters such as pathogenicity or toxin production. The code of conduct presented here is based on best practice principles for scientists and their institutions working with biological resources with a specific focus on micro-organisms. It aims to raise awareness of regulatory needs and to protect researchers, their facilities and stakeholders. It reflects global activities in this area in response to legislation such as that in the USA, the PATRIOT Act of 2001, Uniting and Strengthening America by Providing Appropriate Tools Required to Intercept and Obstruct Terrorism Act of 2001; the Anti-Terrorism Crime and Security Act 2001 and subsequent amendments in the UK; the EU Dual-Use Regulation; and the recommendations of the Organization for Economic Co-operation and Development (OECD), under their Biological Resource Centre (BRC) Initiative at the beginning of the millennium (OECD, 2001). Two project consortia with international partners came together with experts in the field to draw up a Code of Conduct on Biosecurity for BRCs to ensure that culture collections and microbiologists in general worked in a way that met the requirements of such legislation. A BRC is the modern day culture collection that adds value to its holdings and implements common best practice in the collection and supply of strains for research and development. This code of conduct specifically addresses the work of public service culture collections and describes the issues of importance and the controls or

  10. Indonesian perceptions on the implementation of the chemical weapons convention in relation with biosecurity and biosafety

    International Nuclear Information System (INIS)

    April 29, 2007 was marked the 10 year anniversary of the Chemical Weapons Convention (CWC) entry into force and the creation of the OPCW. Many nations throughout the last year were celebrated its commemoration. Compared to the Biological Weapons Convention (BWC) which is now entering the 33rd year of its entry into force, the progress of CWC is running far beyond that convention because CWC is considered the most complete convention which is equipped with a comprehensive verification system. In contrast, up till now there is no formal verification regime to monitor compliance of the BWC. So the national legislation as well as biosafety and biosecurity procedures will be the best regime to prohibit the misuse of biological agents. To some extent, the strategy and method on implementing the provision of CWC are coincident with biosecurity and biosafety procedure due to their dual use characteristics. Concerning CWC, Indonesia which was ratified it in 30 September 1998 has always active in any multilateral meeting and as well as national activities on prohibiting the misuse of chemical weapons. Several courses have also been done in cooperation with OPCW such as Development of Response System Against Chemical Weapons, Basic Training Course for Response Team, National Industry Awareness Workshop, Advance Training for Response Team, National Emergency Response Workshop, as well as setting up 20 sets of individual protective equipment. There have already 7 inspections done by OPCW in Indonesia during 2004-2007 which proved that there were no indications of misuse of chemical processes and its facilities for hostile purposes. However, it does not mean that there is no threat from the possible misuse of chemical and biological agents due to its dual use characteristics. Learnt from Indonesian experiences, there are several constraints on implementing the CWC as well as biosafety and biosecurity. First is the different perception on the biological and chemical threats. For

  11. The main indicators of biosecurity and presence of house mouse (Mus musculus L.) in animal husbandry facilities

    OpenAIRE

    Đedović S.; Bojkovski J.; Jokić G.; Šćepović T.; Vukša M.

    2014-01-01

    Analysis of biosecurity indicators at critical control points intend to prevent undesirable infections in technological chains of production. Product quality is the basis for defining a biosecurity plan under the HACCP concept. General and specific biosecurity measures developed to prevent introductions of infective materials have been at the focus of attention in Serbia in recent years. The house mouse (Mus musculus L.) is usually accused for transferring ...

  12. Global governmentality: Biosecurity in the era of infectious diseases.

    Science.gov (United States)

    Jappah, Jlateh Vincent; Smith, Danielle Taana

    2015-01-01

    This paper uses Foucault's concept of governmentality to examine relationships between globalisation, the threat of infectious diseases and biosecurity. It draws attention to forms of calculated practices which Foucault notes as technologies of power that aim to foster positive demographic and economic trends in societies through the apparatus of security. These practices are employed at the global level with similar ambitions; hence, we adopt the term global governmentality. We discuss the applications of global governmentality by actors in the global core through the apparatus of security and (neo)liberal economic practices. We then provide examples of resistance/contestation from actors mainly in the global periphery through discussions of viral sovereignty; access to essential medicines, including HIV drugs; and health for all as a human right. We conclude that despite the core-periphery power asymmetry and competing paradigms, these developments tend to complement and/or regulate the phenomenon termed global governmentality, which is made evident by the tremendous successes in global health. PMID:25981616

  13. Measuring the costs of biosecurity on poultry farms: a case study in broiler production in Finland

    Directory of Open Access Journals (Sweden)

    Siekkinen Kirsi-Maarit

    2012-02-01

    Full Text Available Abstract Background Farm-level biosecurity provides the foundation for biosecurity along the entire production chain. Many risk management practices are constantly in place, regardless of whether there is a disease outbreak or not. Nonetheless, the farm-level costs of preventive biosecurity have rarely been assessed. We examined the costs incurred by preventive biosecurity for Finnish poultry farms. Methods We used a semi-structured phone interview and obtained results from 17 broiler producers and from 5 hatching egg producers, corresponding to about 10% of all producers in Finland. Results Our results indicate that the average cost of biosecurity is some 3.55 eurocent per bird for broiler producers (0.10 eurocent per bird per rearing day and 75.7 eurocent per bird for hatching egg producers (0.27 eurocent per bird per rearing day. For a batch of 75,000 broilers, the total cost would be €2,700. The total costs per bird are dependent on the annual number of birds: the higher the number of birds, the lower the cost per bird. This impact is primarily due to decreasing labour costs rather than direct monetary costs. Larger farms seem to utilise less labour per bird for biosecurity actions. There are also differences relating to the processor with which the producer is associated, as well as to the gender of the producer, with female producers investing more in biosecurity. Bird density was found to be positively related to the labour costs of biosecurity. This suggests that when the bird density is higher, greater labour resources need to be invested in their health and welfare and hence disease prevention. The use of coccidiostats as a preventive measure to control coccidiosis was found to have the largest cost variance between the producers, contributing to the direct costs. Conclusions The redesign of cost-sharing in animal diseases is currently ongoing in the European Union. Before we can assert how the risk should be shared or resort to the

  14. Evaluation of egg production after adoption of biosecurity strategies by backyard poultry farmers in West Bengal

    Directory of Open Access Journals (Sweden)

    I. Samanta

    2015-02-01

    Full Text Available Aim: On the basis of identified source of major bacterial infections at four agro-climatic zones in West Bengal the cost-effective biosecurity strategy was formulated for backyard poultry farmers. The aim of the present study was to assess the adoption. So, the study was aimed to detect the adoption level of the formulated biosecurity strategy to mitigate the Salmonella and Escherichia coli contamination level in the sources and its correlation with egg production in West Bengal. Materials and Methods: A questionnaire was prepared querying regarding the biosecurity measures presently followed by the farmers, if any and egg production of their birds. Subsequent to the interview the formulated biosecurity strategy was conveyed. After 3 months, the interview with the same questionnaire was conducted to the same farmers to detect their adoption level. Results: The change in practices were noted in certain parameters which differs significantly (p<0.01 or p<0.05. As a consequence, the average egg production/flock was increased in 3 months after adoption of the strategy (618.2±37.77/flock in comparison to last 3 months average before adoption of the strategy (495.3±30.00/flock which also differs significantly (p<0.01. Conclusion: The present study detected the implementation of the biosecurity strategy in backyard poultry farming in West Bengal can substantially benefit the farmers in terms of increased egg production.

  15. Automatic categorization of diverse experimental information in the bioscience literature

    Directory of Open Access Journals (Sweden)

    Fang Ruihua

    2012-01-01

    Full Text Available Abstract Background Curation of information from bioscience literature into biological knowledge databases is a crucial way of capturing experimental information in a computable form. During the biocuration process, a critical first step is to identify from all published literature the papers that contain results for a specific data type the curator is interested in annotating. This step normally requires curators to manually examine many papers to ascertain which few contain information of interest and thus, is usually time consuming. We developed an automatic method for identifying papers containing these curation data types among a large pool of published scientific papers based on the machine learning method Support Vector Machine (SVM. This classification system is completely automatic and can be readily applied to diverse experimental data types. It has been in use in production for automatic categorization of 10 different experimental datatypes in the biocuration process at WormBase for the past two years and it is in the process of being adopted in the biocuration process at FlyBase and the Saccharomyces Genome Database (SGD. We anticipate that this method can be readily adopted by various databases in the biocuration community and thereby greatly reducing time spent on an otherwise laborious and demanding task. We also developed a simple, readily automated procedure to utilize training papers of similar data types from different bodies of literature such as C. elegans and D. melanogaster to identify papers with any of these data types for a single database. This approach has great significance because for some data types, especially those of low occurrence, a single corpus often does not have enough training papers to achieve satisfactory performance. Results We successfully tested the method on ten data types from WormBase, fifteen data types from FlyBase and three data types from Mouse Genomics Informatics (MGI. It is being used in

  16. Expert Opinion on the Perceived Effectiveness and Importance of On-Farm Biosecurity Measures for Cattle and Swine Farms in Switzerland

    OpenAIRE

    Kuster, Karin; Cousin, Marie-Eve; Jemmi, Thomas; Schüpbach-Regula, Gertraud; Magouras, Ioannis

    2015-01-01

    Biosecurity is crucial for safeguarding livestock from infectious diseases. Despite the plethora of biosecurity recommendations, published scientific evidence on the effectiveness of individual biosecurity measures is limited. The objective of this study was to assess the perception of Swiss experts about the effectiveness and importance of individual on-farm biosecurity measures for cattle and swine farms (31 and 30 measures, respectively). Using a modified Delphi method, 16 Swiss livestock ...

  17. Expert Opinion on the Perceived Effectiveness and Importance of On-Farm Biosecurity Measures for Cattle and Swine Farms in Switzerland.

    OpenAIRE

    Kuster, Karin; Cousin, Marie-Eve; Jemmi, Thomas; Schüpbach, Gertraud; Magouras, Ioannis

    2015-01-01

    Biosecurity is crucial for safeguarding livestock from infectious diseases. Despite the plethora of biosecurity recommendations, published scientific evidence on the effectiveness of individual biosecurity measures is limited. The objective of this study was to assess the perception of Swiss experts about the effectiveness and importance of individual on-farm biosecurity measures for cattle and swine farms (31 and 30 measures, respectively). Using a modified Delphi method, 16 Swiss livestock ...

  18. Associations between biosecurity and outbreaks of canine distemper on Danish mink farms in 2012-2013

    DEFF Research Database (Denmark)

    Gregers-Jensen, Louise; Agger, Jens Frederik; Hammer, Anne Sofie Vedsted;

    2015-01-01

    farms, indicating that the control farms had a better biosecurity or were not equally exposed to canine distemper virus. Generally, all farms had very few specific precautions at the gate entrance in respect to human visitors as well as animals. The use of biosecurity measures was very variable in both...... case and control farms. Not using plastic boot covers, presence of dogs and cats, presence of demarcated area for changing clothes when entering and leaving the farm area and presence of hand washing facilities significantly lowered the odds of the farm having a canine distemper virus outbreak....... The results of the study indicate that consistent use of correct vaccination strategies, implementation of biosecurity measures and limiting human and animal access to the mink farm can be important factors in reducing the risk for canine distemper outbreaks....

  19. Biosecurity measures for backyard poultry in developing countries: a systematic review

    Directory of Open Access Journals (Sweden)

    Conan Anne

    2012-12-01

    Full Text Available Abstract Background Poultry represents an important sector in animal production, with backyard flocks representing a huge majority, especially in the developing countries. In these countries, villagers raise poultry to meet household food demands and as additional sources of incomes. Backyard production methods imply low biosecurity measures and high risk of infectious diseases, such as Newcastle disease or zoonosis such as Highly Pathogenic Avian Influenza (HPAI. We reviewed literature on biosecurity practices for prevention of infectious diseases, and published recommendations for backyard poultry and assessed evidence of their impact and feasibility, particularly in developing countries. Documents were sourced from the Food and Agriculture Organization (FAO website, and from Pubmed and Google databases. Results A total of 62 peer-reviewed and non-referred documents were found, most of which were published recently (after 2004 and focused on HPAI/H5N1-related biosecurity measures (64%. Recommendations addressed measures for flock management, feed and water management, poultry trade and stock change, poultry health management and the risk to humans. Only one general guideline was found for backyard poultry-related biosecurity; the other documents were drawn up for specific developing settings and only engaged their authors (e.g. consultants. These national guidelines written by consultants generated recommendations regarding measures derived from the highest standards of commercial poultry production. Although biosecurity principles of isolation and containment are described in most documents, only a few documents were found on the impact of measures in family poultry settings and none gave any evidence of their feasibility and effectiveness for backyard poultry. Conclusions Given the persistent threat posed by HPAI/H5N1 to humans in developing countries, our findings highlight the importance of encouraging applied research toward identifying

  20. Reflective Writing as a Tool for Assessing Teamwork in Bioscience: Insights into Student Performance and Understanding of Teamwork

    Science.gov (United States)

    Mayne, Lynne

    2012-01-01

    To ensure a modern bioscience curriculum that responds to the current needs of stakeholders, there is a need to embed a range of generic capabilities that enables graduates to succeed in and contribute to a rapidly changing world, as well as building strong bioscience skills and knowledge. The curriculum must also prepare students for a rapidly…

  1. Biosecurity and yield improvement technologies are strategic complements in the fight against food insecurity.

    Directory of Open Access Journals (Sweden)

    David C Cook

    Full Text Available The delivery of food security via continued crop yield improvement alone is not an effective food security strategy, and must be supported by pre- and post-border biosecurity policies to guard against perverse outcomes. In the wake of the green revolution, yield gains have been in steady decline, while post-harvest crop losses have increased as a result of insufficiently resourced and uncoordinated efforts to control spoilage throughout global transport and storage networks. This paper focuses on the role that biosecurity is set to play in future food security by preventing both pre- and post-harvest losses, thereby protecting crop yield. We model biosecurity as a food security technology that may complement conventional yield improvement policies if the gains in global farm profits are sufficient to offset the costs of implementation and maintenance. Using phytosanitary measures that slow global spread of the Ug99 strain of wheat stem rust as an example of pre-border biosecurity risk mitigation and combining it with post-border surveillance and invasive alien species control efforts, we estimate global farm profitability may be improved by over US$4.5 billion per annum.

  2. Biosecurity State in Gamecock (Gallus gallus Breeding Farms in Yacuanquer, Nariño, Colombia

    Directory of Open Access Journals (Sweden)

    Juan Manuel Astaíza Martínez

    2015-09-01

    Full Text Available The poultry industry in Colombia is sanitarily controlled and regulated; therefore, gamecock breeding farms should be regulated, but to this moment there are no studies about the biosecurity measurements implemented, which is a growing concern due to the sanitary impact this might have on the poultry industry. The goal of this work was to assess the knowledge and application of biosecurity norms in gamecock (Gallus gallus breeding farms from the Yacuanquer municipality, in Nariño, Colombia, as regulated by Resolution 3642 of August 21st of 2013, issued by the Instituto Colombiano Agropecuario. 157 breeders were surveyed, from which 88.54% does not recognize the biosecurity concept and does not control the entrance of people not related to the farm; 61.15% does not disinfect locations; 100% does not keep a pediluvium at the entrance of the farm nor do they carry out disinfection procedures for their vehicles; only 23.57% does a sanitary break inside their breeding farms and 63.7% does not put a quarantine period in place for the new specimens they acquire; 64.33% does not vaccinate and 98.09% does not have any veterinary advice. In conclusion, it was established that gamecock breeders in Yacuanquer do not know and have not implemented biosecurity measurements, which represents a risk factor for the poultry industry of the region.

  3. Design of an Integrated Team Project as Bachelor Thesis in Bioscience Engineering

    Science.gov (United States)

    Peeters, Marie-Christine; Londers, Elsje; Van der Hoeven, Wouter

    2014-01-01

    Following the decision at the KU Leuven to implement the educational concept of guided independent learning and to encourage students to participate in scientific research, the Faculty of Bioscience Engineering decided to introduce a bachelor thesis. Competencies, such as communication, scientific research and teamwork, need to be present in the…

  4. Call for Papers--Bioscience Methods (ISSN 1925-1920)

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Bioscience Methods (BM) (ISSN 1925-1920) is a new launched, open access and peer-revi- ewed journal that dedicates to publish the original research papers involving in innovative technologies and novel experimental arts within the fields ofbiosciences.

  5. Call for papers--Bioscience Methods (ISSN 1925-1920)

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Bioscience Methods (BM) (ISSN 1925-1920) is a new launched, open access and peer-reviewed journal that dedicates to publish the original research papers involving in innovative technologies and novel experimental arts within the fields ofbiosciences.

  6. Call for papers—Bioscience Methods(ISSN 1925-1920)

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Bioscience Methods(BM)(ISSN 1925-1920) is a new launched,open access and peer-reviewed journal that dedicates to publish the original research papers involving in innovative technologies and novel experimental arts within the fields ofbiosciences.

  7. Development of an Electronic Role-Play Assessment Initiative in Bioscience for Nursing Students

    Science.gov (United States)

    Craft, Judy; Ainscough, Louise

    2015-01-01

    Devising authentic assessments for subjects with large enrolments is a challenge. This study describes an electronic role-play assessment for approximately 600 first-year nursing students to learn and apply pathophysiology (bioscience) concepts to nursing practice. Students used Microsoft Office PowerPoint[R] to prepare electronic role-plays both…

  8. Review of the biosecurity in different poultry sectors to prevent highly pathogenic avian influenza in Tanzania

    International Nuclear Information System (INIS)

    Distribution of the poultry operations in Tanzania in accordance to the FAO classification system of sectors 1 - 4 has been done and a review of biosecurity in each of those production systems documented. It was found out that typical sector 1 characterised by an industrial integrated system with high level of biosecurity is non-existent in the country. Sector 2 represents high levels of commercial poultry production system with moderate to high biosecurity, which involve raising parent stock (PS) and operating Hatcheries mainly but also raise commercial poultry - layers and/or broilers.19 farms were identified to fall under this category located in Regions of Pwani (6), Dar es Salaam (6), Arusha (2), Mwanza (2), Mbeya (1), Kilimanjaro (2). Sector 3 represents farms involved in commercial poultry production of eggs and broiler production from hybrid chickens with low to minimal biosecurity and birds/products usually enter live bird markets. 25,624 small-scale commercial production farmers raising commercial layers and broilers were classified in this category. Village, peri-urban or urban backyard production with minimal biosecurity and birds/products consumed locally is classified as FAO sector 4 and included 34 million local village chickens kept by 2,992,145 smallholder households in Tanzania The objectives of the study were to identify areas of possible biosecurity risks in the production cycle in each of the poultry production sectors, with special emphasis on sectors 3 and 4 in Tanzania so as to outline strategies to minimise the occurrence of the HPAI at all levels of poultry production, distribution, processing and marketing, thereby reducing the risk of human infection by bird flu virus. The study will contribute to drawing attention of all those handling poultry and its byproducts, all along the food supply chain. The methodology of the study was basically a desktop study that involved collection of data and documents from various sources and extensive

  9. Determinants of Knowledge and Biosecurity Preventive Behaviors for Highly Pathogenic Avian Influenza Risk Among Chinese Poultry Farmers.

    Science.gov (United States)

    Cui, Bin; Liu, Zong Ping

    2016-06-01

    Biosecurity measures are the first line of defense against highly pathogenic avian influenza (HPAI) on farms. It is generally recognized that an individual's behavior can be influenced by the knowledge they possess. However, empirical study has not reported an association between poultry producers' awareness of HPAI symptoms and their actual biosecurity actions. The aim of this study is to classify knowledge items of HPAI by exploratory factor analysis (EFA) and to examine the determinants of different types of knowledge and the effect of different types of knowledge on biosecurity preventive behaviors (BPBs). The survey (n = 297) was conducted using a questionnaire to measure the level of awareness of items related to HPAI and the actual adoption of BPBs among poultry farmers in the Chinese province of Jiangsu. The EFA revealed three main types of knowledge, which were categorized as avian influenza (AI) epidemic characteristics, primary biosecurity preventive knowledge (basic biosecurity preventive knowledge against AI), and essential biosecurity preventive knowledge (crucial biosecurity preventive knowledge against infection of AI). Multivariate regression showed that only poultry farmers' awareness of essential biosecurity preventive knowledge was positively associated with their actual BPBs. Additionally, educational attainment, number of years of experience raising poultry, farming operation size, and training were associated both with BPB and most of the knowledge factors or knowledge items. Training of existing poultry farmers is probably a feasible scheme; furthermore, the training should focus on the essential biosecurity preventive knowledge. On the other hand, policy initiatives to encourage large-scale poultry farming while discouraging small-scale backyard poultry husbandry would be an effective method of improving the management standards of rural poultry farming. PMID:27309291

  10. The biosecurity status and its associations with production and management characteristics in farrow-to-finish pig herds.

    Science.gov (United States)

    Postma, M; Backhans, A; Collineau, L; Loesken, S; Sjölund, M; Belloc, C; Emanuelson, U; Grosse Beilage, E; Stärk, K D C; Dewulf, J

    2016-03-01

    Disease prevention through biosecurity measures is believed to be an important factor for improvement of the overall health status in animal production. This study aimed at assessing the levels of implementation of biosecurity measures in pig production in four European Union (EU) countries and to describe possible associations between the biosecurity level and farm and production characteristics. A cross-sectional study was conducted in 232 farrow-to-finish pig herds in Belgium, France, Germany and Sweden between December 2012 and December 2013. The biosecurity status in each of these herds was described and quantified by using the risk-based scoring tool Biocheck.UGentTM (www.biocheck.ugent.be). Production and management characteristics, obtained from the herd management system and by interviewing the farmer, were analysed for their association with the biosecurity level. A causal path was designed to study statistical associations. The results showed that there was substantial room for improvement in the biosecurity status on many pig farms. Significant differences (Page and the mortality till weaning were highly associated with the number of weaned piglets per sow per year. The negative association observed between the biosecurity level and the estimated frequency of treatment against certain clinical signs of disease as a proxy for disease incidence is consistent with the hypothesis that a higher biosecurity level results in healthier animals. These findings promote an improved biosecurity status at pig farms and are of relevance in the discussion on alternative ways to keep animals healthy with a reduced necessity of antimicrobials; Prevention is better than cure! PMID:26567800

  11. Demand for Interdisciplinary Laboratories for Physiology Research by Undergraduate Students in Biosciences and Biomedical Engineering

    Science.gov (United States)

    Clase, Kari L.; Hein, Patrick W.; Pelaez, Nancy J.

    2008-01-01

    Physiology as a discipline is uniquely positioned to engage undergraduate students in interdisciplinary research in response to the 2006-2011 National Science Foundation Strategic Plan call for innovative transformational research, which emphasizes multidisciplinary projects. To prepare undergraduates for careers that cross disciplinary…

  12. An "in silico" Bioinformatics Laboratory Manual for Bioscience Departments: "Prediction of Glycosylation Sites in Phosphoethanolamine Transferases"

    Science.gov (United States)

    Alyuruk, Hakan; Cavas, Levent

    2014-01-01

    Genomics and proteomics projects have produced a huge amount of raw biological data including DNA and protein sequences. Although these data have been stored in data banks, their evaluation is strictly dependent on bioinformatics tools. These tools have been developed by multidisciplinary experts for fast and robust analysis of biological data.…

  13. On-farm characteristics and biosecurity protocols for small-scale swine producers in eastern Australia.

    Science.gov (United States)

    Schembri, N; Hernandez-Jover, M; Toribio, J-A L M L; Holyoake, P K

    2015-01-01

    Pigs are considered high risk for the introduction and spread of foot and mouth disease (FMD) in Australia. Facilities where animals from different origins are commingled, such as saleyards, pose a high risk for disease spread. Sound on-farm management practices and biosecurity protocols are the first line of defence against a potential on-farm disease outbreak. This study evaluated the practices of 104 producers (vendors who sold pigs and purchasers of live pigs for grow-out) who traded pigs at 6 peri-urban and rural saleyards in eastern Australia. Specifically, management and on-farm biosecurity practices were assessed using an in-depth questionnaire. Univariable and multivariable logistic regression analyses were used to investigate (1) producer associations: producer type, State, motivation to keep pigs, farm type, gender, years having owned pigs, and the acquisition of formal livestock qualifications; and (2) pig associations: herd size, housing, management (husbandry and feeding) practices and biosecurity (including pig movement) practices. Backyard operations (footwear precautions (P=0.007) and ask visitors about prior pig contacts (P=0.004). Approximately 40% of backyard and small-scale producers reported not having any quarantine practices in place for incoming pigs, compared to only 9.1% among larger producers. The main reasons cited for not adopting on-farm biosecurity practices in this study included having no need on their property (43.1%) and a lack of information and support (by the industry and/or authorities; 18.5%). Up to three-quarters of all producers maintained an open breeding herd, regularly introducing new pigs to the main herd. Saleyards are an important source of income for backyard and small-scale producers as well as an important risk factor for the introduction and dissemination of endemic and emerging animal diseases. Differing management and biosecurity practices as well as the motivations of these producers keeping pigs in small

  14. Division of energy biosciences: Annual report and summaries of FY 1995 activities

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    The mission of the Division of Energy Biosciences is to support research that advances the fundamental knowledge necessary for the future development of biotechnologies related to the Department of Energy`s mission. The departmental civilian objectives include effective and efficient energy production, energy conservation, environmental restoration, and waste management. The Energy Biosciences program emphasizes research in the microbiological and plant sciences, as these understudied areas offer numerous scientific opportunities to dramatically influence environmentally sensible energy production and conservation. The research supported is focused on the basic mechanisms affecting plant productivity, conversion of biomass and other organic materials into fuels and chemicals by microbial systems, and the ability of biological systems to replace energy-intensive or pollutant-producing processes. The Division also addresses the increasing number of new opportunities arising at the interface of biology with other basic energy-related sciences such as biosynthesis of novel materials and the influence of soil organisms on geological processes.

  15. Effect of envelope material on biosecurity during emergency bovine mortality composting.

    Science.gov (United States)

    Glanville, T D; Ahn, H K; Richard, T L; Harmon, J D; Reynolds, D L; Akinc, S

    2013-02-01

    The biosecurity of composting as an emergency disposal method for cattle mortalities caused by disease was evaluated by conducting full-scale field trials begun during three different seasons and using three different envelope materials. Process biosecurity was significantly affected by the envelope material used to construct the composting matrix. Internal temperatures met USEPA Class A time/temperature criteria for pathogen reduction in 89%, 67%, and 22%, respectively of seasonal test units constructed with corn silage, straw/manure, or ground cornstalks. In trials begun in the winter, survival times of vaccine strains of avian encephalomyelitis and Newcastle disease virus were noticeably shorter in silage test units than in the other two materials, but during summer/spring trials survival times in ground cornstalk and straw/manure test units were similar to those in test units constructed with silage.

  16. The molecular biology revolution and the rise of bioscience megacentres in North America and Europe

    OpenAIRE

    Philip Cooke

    2004-01-01

    This paper focuses on 'triple helix' effects in biosciences. Scientific change can have profound socioeconomic effects. The molecular biology revolution tilted pharmaceuticals production away from its fine chemistry path dependence into microbiology and biotechnology. The key to any triple helix effects has thus shifted to universities and spinouts buttressed with burgeoning public funding, leaving 'big pharma' increasingly playing the role of licenser and marketer of bought-in therapeutic tr...

  17. Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research †

    OpenAIRE

    Carol Kilkenny; Browne, William J.; Cuthill, Innes C; Michael Emerson; Altman, Douglas G.

    2014-01-01

    In the last decade the number of bioscience journals has increased enormously, with many filling specialised niches reflecting new disciplines and technologies. The emergence of open-access journals has revolutionised the publication process, maximising the availability of research data. Nevertheless, a wealth of evidence shows that across many areas, the reporting of biomedical research is often inadequate, leading to the view that even if the science is sound, in many cases the publications...

  18. The interministerial commission on biosecurity and genetically modified organisms in Mexico

    International Nuclear Information System (INIS)

    With the development of transgenic technology related to agriculture, Mexico has taken the initiative to develop a regulatory framework to deal with issues related to risk assessment, biosecurity and biodiversity. An Interministerial Commission has been formed which oversees all aspects of genetically modified organisms (GMOs). This paper describes in detail the responsibilities of the different bodies involved in the Interministerial Commission, and discusses some of the issues related to the introduction of genetically modified maize. (author)

  19. Digitizing and Securing Archived Laboratory Notebooks

    Science.gov (United States)

    Caporizzo, Marilyn

    2008-01-01

    The Information Group at Millipore has been successfully using a digital rights management tool to secure the email distribution of archived laboratory notebooks. Millipore is a life science leader providing cutting-edge technologies, tools, and services for bioscience research and biopharmaceutical manufacturing. Consisting of four full-time…

  20. Mathematical theories in biosecurity%数学在生物安全中的应用

    Institute of Scientific and Technical Information of China (English)

    刘巾杰; 祖正虎; 许晴; 张文斗; 徐致靖; 郑涛

    2014-01-01

    用数学建模的方法对生物事件进行抽象,揭示其发生发展机制,可以使人们更深刻认识生物事件成灾规律,从而为生物事件的应急准备和有效处置提供更为精准的科学支持,对国家生物防御能力建设具有重要意义。该文概析了数学理论作为研究与分析工具在生物防御领域中的应用,展望了该领域研究发展趋势。%Modeling biosecurity events based on mathematical theories to reveal the inherent mechanism can shed light on the development of biosecurity events and offer accurate scientific support to emergency preparation and response , con-tributing much to national biodefense capability .This paper reviews the applications of mathematical theories as a research and analytic tool in biosecurity and discusses the trends of development in this field .

  1. Bioculture System: Expanding ISS Space Bioscience Capabilities for Fundamental Stem Cell Research and Commercial Applications

    Science.gov (United States)

    Blaber, Elizabeth; Dvorochkin, Natalya; Almeida, Eduardo; Fitzpatrick, Garret; Ellingson, Lance; Mitchell, Sarah; Yang, Anthony; Kosnik, Cristine; Rayl, Nicole; Cannon, Tom; Austin, Edward; Sato, Kevin

    With the recent call by the 2011 Decadal Report and the 2010 Space Biosciences Roadmap for the International Space Station (ISS) to be used as a National Laboratory for scientific research, there is now a need for new laboratory instruments on ISS to enable such research to occur. The Bioculture System supports the extended culturing of multiple cell types and microbiological specimens. It consists of a docking station that carries ten independent incubation units or ‘Cassettes’. Each Cassette contains a cooling chamber (5(°) C) for temperature sensitive solutions and samples, or long duration fluids and sample storage, as well as an incubation chamber (ambient up to 42(°) C). Each Cassette houses an independent fluidics system comprised of a biochamber, medical-grade fluid tubing, medium warming module, oxygenation module, fluid pump, and sixteen solenoid valves for automated biochamber injections of sampling. The Bioculture System provides the user with the ability to select the incubation temperature, fluid flow rate and automated biochamber sampling or injection events for each separate Cassette. Furthermore, the ISS crew can access the biochamber, media bag, and accessory bags on-orbit using the Microgravity Science Glovebox. The Bioculture System also permits initiation of cultures, subculturing, injection of compounds, and removal of samples for on-orbit processing using ISS facilities. The Bioculture System therefore provides a unique opportunity for the study of stem cells and other cell types in space. The first validation flight of the Bioculture System will be conducted on SpaceX5, consisting of 8 Cassettes and lasting for 30-37 days. During this flight we plan to culture two different mammalian cell types in bioreactors: a mouse osteocytic-like cell line, and human induced pluripotent stem cell (iPS)-derived cardiomyocytes. Specifically, the osteocytic line will enable the study of a type of cell that has been flown on the Bioculture System

  2. Development of a dedicated beam forming system for material and bioscience research with high intensity, small field electron beam of LILLYPUT 3 accelerator at Wroclaw Technology Park

    CERN Document Server

    Adrich, Przemysław; Wilk, Piotr; Chorowski, Maciej; Poliński, Jarosław; Bogdan, Piotr

    2016-01-01

    The primary use of the LILLYPUT 3 accelerator at the Nondestructive Testing Laboratory at Wroclaw Technology Park is X-ray radiography for nondestructive testing, including R&D of novel techniques for industrial and medical imaging. The scope of possible applications could be greatly extended by providing a system for irradiation with electron beam. The purpose of this work was to design such a system, especially for high dose rate, small field irradiations under cryogenic conditions for material and bioscience research. In this work, two possible solutions, based either on beam scanning or scattering and collimation, were studied and compared. It was found that under existing conditions efficiency of both systems would be comparable. The latter one was adopted due to its simplicity and much lower cost. The system design was optimized by means of detailed Monte Carlo modeling. The system is being currently fabricated at National Centre for Nuclear Research in \\'Swierk.

  3. Status and prospect of global biosecurity%当前国际生物安全形势与展望

    Institute of Scientific and Technical Information of China (English)

    郑涛; 黄培堂; 沈倍奋

    2012-01-01

    Biosecurity refers to the ability of a country to respond effectively to biological and biotechnical threats, safeguard and protect national security and interest in the era of globalization. Based on analysis of the Biological and Toxin Weapons Convention, bioterrorism, infectious diseases, biotechnology abuse and biosecurity of CM foods,this article argues that the current situation in global biosecurity as a whole tends to become severe, but biosecurity in China is becoming stable. This article recommends that China should attach importance to sustainable development of biosecurity.%生物安全是指全球化时代国家有效应对生物及生物技术因素的影响和威胁,维护和保障自身安全与利益的状态和能力.本文通过对《禁止生物武器公约》履约、生物恐怖、传染病以及生物技术谬用、转基因生物安全等的形势分析,认为总体上,国际生物安全形势趋于负面,我国生物安全形势趋于平稳,建议国家重视生物安全的可持续发展.

  4. Indirect Transmission of Influenza A Virus between Pig Populations under Two Different Biosecurity Settings.

    Directory of Open Access Journals (Sweden)

    Matt W Allerson

    Full Text Available Respiratory disease due to influenza virus is common in both human and swine populations around the world with multiple transmission routes capable of transmitting influenza virus, including indirect routes. The objective of this study was to evaluate the role of fomites in influenza A virus (IAV transmission between pig populations separated by two different biosecurity settings. Thirty-five pigs were divided into four experimental groups: 10 pigs (1 replicate were assigned to the infected group (I, 10 pigs (2 replicates of 5 pigs were assigned to the low biosecurity sentinel group (LB, 10 pigs (2 replicates of 5 pigs were assigned to the medium biosecurity sentinel group (MB, and 5 pigs (1 replicate were assigned to the negative control group (NC. Eight of 10 pigs in the infected group were inoculated with IAV and 36 hours following inoculation, personnel movement events took place in order to move potentially infectious clothing and personal protective equipment (PPE to sentinel pig rooms. Following contact with the infected group, personnel moved to the MB group after designated hygiene measures while personnel moved directly to the LB group. Nasal swabs and blood samples were collected from pigs to assess IAV infection status and fomites were sampled and tested via RRT-PCR. All experimentally inoculated pigs were infected with IAV and 11 of the 144 fomite samples collected following contact with infected pigs were low level positive for IAV genome. One replicate of each sentinel groups LB and MB became infected with IAV and all five pigs were infected over time. This study provides evidence that fomites can serve as an IAV transmission route from infected to sentinel pigs and highlights the need to focus on indirect routes as well as direct routes of transmission for IAV.

  5. Rapid identification of bio-molecules applied for detection of biosecurity agents using rolling circle amplification.

    Directory of Open Access Journals (Sweden)

    Jenny Göransson

    Full Text Available Detection and identification of pathogens in environmental samples for biosecurity applications are challenging due to the strict requirements on specificity, sensitivity and time. We have developed a concept for quick, specific and sensitive pathogen identification in environmental samples. Target identification is realized by padlock- and proximity probing, and reacted probes are amplified by RCA (rolling-circle amplification. The individual RCA products are labeled by fluorescence and enumerated by an instrument, developed for sensitive and rapid digital analysis. The concept is demonstrated by identification of simili biowarfare agents for bacteria (Escherichia coli and Pantoea agglomerans and spores (Bacillus atrophaeus released in field.

  6. Biosecurity in 116 Danish fattening swineherds: descriptive results and factor analysis

    DEFF Research Database (Denmark)

    Boklund, Anette; Alban, L.; Mortensen, Sten;

    2004-01-01

    producers purchased weaners from a market. Almost all herds (95%) received weaners from one sow herd at one time, and only one herd received from >5 sow herds in one batch. Twenty-one percent did not use an effective barrier between the loading area and the stables when delivering pigs for slaughter. Entry...... rooms (in which clothing and boots are changed) were common at the farm, and the numbers of visitors were generally low ( 3.10). A site scoring high on factor 1 was a large SPF herd, which received weaners from a single source, had biosecurity requirements for the transport vehicles, and had a high...

  7. A cross-sectional study on biosecurity practices and communication networks of poultry exhibition in Australia.

    Science.gov (United States)

    Hernández-Jover, Marta; Schemann, Kathrin; Toribio, Jenny-Ann L M L

    2013-07-01

    Poultry exhibitors are perceived to pose a biosecurity risk due to the high frequency of movements of birds and the close contact between birds at poultry shows. This cross-sectional study assessed the risks posed by poultry exhibitors in Australia using face-to-face interviews (n=46) at eight poultry shows and a postal survey. Univariable and multivariable logistic regression analyses were used to investigate associations between age, sex, location, number of birds, number of shows attended per year and distance travelled to a show, with biosecurity and communication practices. A total of 357 (29.1%) exhibitors responded to the postal survey. Among all participants (n=403), most had owned poultry for more than 15 years (71.9%), kept less than 200 birds (83.4%), mainly chicken (96.7%) and waterfowl (17.8%), and reported not having any commercial poultry operation within 5 km of their property (85.4%). Despite most exhibitors (90.8%) having at least some knowledge of biosecurity principles; some of their practices could pose a risk for disease introduction and spread. Most exhibitors kept their birds with outdoor access (87.0%) and 67.0% of exhibitors reported contact of wild birds with domestic birds being possible. Only 60% and 40.6% of exhibitors cleaned transport cages after each use and isolated birds for over two weeks, respectively, with men and exhibitors keeping more birds less likely (P=0.003) to conduct this practice. Most exhibitors (75.0%) attended more than 5 shows per year, travelling long distances (up to 1000 km) to attend a show. Although most exhibitors would source and sell their birds from and to other exhibitors and at poultry shows, some reported sourcing (15.2%) and selling (25.3%) their birds at live bird markets. In addition, contact with veterinarians was low (23.1%), with younger exhibitors and women more likely to contact a veterinarian than older exhibitors (P=0.006) and men (P=0.017). Other poultry exhibitors were reported as the most

  8. Strengthening Biosecurity in Iraq: Development of a National Biorisk Management System.

    Science.gov (United States)

    Al Jewari, Mahdi F H; Koblentz, Gregory D

    2016-01-01

    Since 2004, the Republic of Iraq has undertaken a concerted effort to comply with all of its international obligations to prevent the proliferation and the use of chemical, biological, radiological, and nuclear (CBRN) weapons. A centerpiece of this effort is Iraq's development of a National Biorisk Management System. The Iraqi National Monitoring Authority (INMA), which is responsible for CBRN security and non-proliferation in Iraq, has played a key role in establishing this system. This article provides an overview of Iraq's international non-proliferation commitments, describes the legal and organizational steps it has taken to implement these commitments, and examines current initiatives to strengthen Iraq's biosecurity. PMID:26952002

  9. National biosecurity approaches, plans and programmes in response to diseases in farmed aquatic animals: evolution, effectiveness and the way forward

    DEFF Research Database (Denmark)

    Håstein, T.; Binde, M.; Hine, M.;

    2008-01-01

    and Manual of Diagnostic Tests for Aquatic Animals serve as an excellent framework. Using examples from a few countries and selected diseases, this paper provides a general overview of the development of approaches to implementing biosecurity strategies, including those emerging in the national legislation......The rapid increase in aquaculture production and trade, and increased attention to the negative effects of disease, are becoming stimuli for developing national biosecurity strategies for farmed fisheries, for which the World Organisation for Animal Health (OIE) Aquatic Animal Health Code...

  10. An exploration of the drivers to bio-security collective action among a sample of UK cattle and sheep farmers.

    Science.gov (United States)

    Heffernan, Claire; Nielsen, Louise; Thomson, Kim; Gunn, George

    2008-11-17

    At present, collective action regarding bio-security among UK cattle and sheep farmers is rare. Despite the occurrence of catastrophic livestock diseases such as bovine spongiform encephalopathy (BSE) and foot and mouth disease (FMD), within recent decades, there are few national or local farmer-led animal health schemes. To explore the reasons for this apparent lack of interest, we utilised a socio-psychological approach to disaggregate the cognitive, emotive and contextual factors driving bio-security behaviour among cattle and sheep farmers in the United Kingdom (UK). In total, we interviewed 121 farmers in South-West England and Wales. The main analytical tools included a content, cluster and logistic regression analysis. The results of the content analysis illustrated apparent 'dissonance' between bio-security attitudes and behaviour.(1) Despite the heavy toll animal disease has taken on the agricultural economy, most study participants were dismissive of the many measures associated with bio-security. Justification for this lack of interest was largely framed in relation to the collective attribution or blame for the disease threats themselves. Indeed, epidemic diseases were largely related to external actors and agents. Reasons for outbreaks included inadequate border control, in tandem with ineffective policies and regulations. Conversely, endemic livestock disease was viewed as a problem for 'bad' farmers and not an issue for those individuals who managed their stock well. As such, there was little utility in forming groups to address what was largely perceived as an individual problem. Further, we found that attitudes toward bio-security did not appear to be influenced by any particular source of information per se. While strong negative attitudes were found toward specific sources of bio-security information, e.g. government leaflets, these appear to simply reflect widely held beliefs. In relation to actual bio-security behaviours, the logistic

  11. Division of Energy Biosciences annual report and summaries of FY 1996 activities

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-04-01

    The mission of the Division of Energy Biosciences is to support research that advances the fundamental knowledge necessary for the future development of biotechnologies related to the Department of Energy`s mission. The departmental civilian objectives include effective and efficient energy production, energy conservation, environmental restoration, and waste management. The Energy Biosciences program emphasizes research in the microbiological and plant sciences, as these understudied areas offer numerous scientific opportunities to dramatically influence environmentally sensible energy production and conservation. The research supported is focused on the basic mechanism affecting plant productivity, conversion of biomass and other organic materials into fuels and chemicals by microbial systems, and the ability of biological systems to replace energy-intensive or pollutant-producing processes. The Division also addresses the increasing number of new opportunities arising at the interface of biology with other basic energy-related sciences such as biosynthesis of novel materials and the influence of soil organisms on geological processes. This report gives summaries on 225 projects on photosynthesis, membrane or ion transport, plant metabolism and biosynthesis, carbohydrate metabolism lipid metabolism, plant growth and development, plant genetic regulation and genetic mechanisms, plant cell wall development, lignin-polysaccharide breakdown, nitrogen fixation and plant-microbial symbiosis, mechanism for plant adaptation, fermentative microbial metabolism, one and two carbon microbial metabolism, extremophilic microbes, microbial respiration, nutrition and metal metabolism, and materials biosynthesis.

  12. Biosecurity and Disinfection Controls of Poultry Microbial Pathogen Infections in Nigeria

    Directory of Open Access Journals (Sweden)

    Irene U. Chima

    2012-03-01

    Full Text Available In Nigeria, industrial poultry production occupies a place of pride among the livestock enterprises due to its rapid monetary turnover. However, Intensive poultry farming provides the optimum conditions for the concentration of disease causing pathogens and transmission. The presence of these diseases has created the need for the control of poultry pathogens in the intensive farming system. Microbiological contamination can be prevented and controlled using proper management practices and healthcare products such as disinfectants. Disinfection consists of destroying disease-producing microbes by chemical and physical means. Hygiene involves the setting up of physical barriers to restrict the access of disease causing agents to the flock and to limit the spread of infectious materials. Biosecurity on the other hand is the protection of poultry flock from any type of infectious agents, whether viral, bacterial, fungi or parasitic in nature. In many developing countries, such as Nigeria, provision for biosecurity are usually inadequate due to; outdated laws and inadequate legal infrastructure; lack of resources, budget and infrastructure for inspection and enforcement; poor cooperation between agencies; lack of technical resources and infrastructure for risk assessment, etc. Measures to enhance safety of food and good quality poultry products from farm to table are however key concerns for all stakeholders in the industry. Since Global concerns about poultry pathogen play a prime role in poultry exports and food policy decisions in international trade, Nigerian poultry farmers need proper diseases control environment in order to sustain asses to international trade.

  13. The role of plant biosecurity in preventing and controlling emerging plant virus disease epidemics.

    Science.gov (United States)

    Rodoni, B

    2009-05-01

    A number of research strategies have been initiated over the last decade to enhance plant biosecurity capacity at the pre-border, border and post-border frontiers. In preparation for emerging plant virus epidemics, diagnostic manuals for economically important plant viruses that threaten local industries have been developed and validated under local conditions. Contingency plans have also been prepared that provide guidelines to stakeholders on diagnostics, surveillance, survey strategies, epidemiology and pest risk analysis. Reference collections containing validated positive virus controls have been expanded to support a wide range of biosecurity sciences. Research has been conducted to introduce high throughput diagnostic capabilities and the design and development of advanced molecular techniques to detect virus genera. These diagnostic tools can be used by post entry quarantine agencies to detect known and unknown plant viral agents. Pre-emptive breeding strategies have also been initiated to protect plant industries if and when key exotic viruses become established in localized areas. With the emergence of free trade agreements between trading partners there is a requirement for quality assurance measures for pathogens, including viruses, which may occur in both the exporting and importing countries. These measures are required to ensure market access for the exporting country and also to minimize the risk of the establishment of a damaging virus epidemic in the importing country. PMID:19152816

  14. Backyard chicken keeping in the Greater London Urban Area: welfare status, biosecurity and disease control issues.

    Science.gov (United States)

    Karabozhilova, I; Wieland, B; Alonso, S; Salonen, L; Häsler, B

    2012-01-01

    1. The aim of the study was to collect baseline data on welfare, biosecurity and diseases of backyard chickens kept in the Greater London Urban Area (GLUA), United Kingdom (UK). 2. A total of 65 backyard chicken flock-keepers were recruited from May to July 2010 through adverts on websites, at City farms, veterinary practices and pet feed stores and surveyed by means of a questionnaire. A total of 30 responses were suitable for analysis. 3. Information on keepers' and flocks' characteristics, housing and husbandry practices and owners' knowledge of health problems in chickens and zoonotic diseases was collected. A welfare assessment protocol was developed and the flocks assessed accordingly. 4. Results showed that chickens were generally provided with living conditions that allowed them to perform their natural behaviours. 5. Most of the flock owners did not comply with the regulations of the Department for Environment, Food and Rural Affairs (Defra) on the feeding of catering waste. 6. Disease prevention measures such as vaccination and biosecurity, including limiting the access of human visitors, wild birds and rodents to the flocks were rare. 7. A lack of avian and zoonotic disease knowledge and awareness among the owners has implications for disease control and highlights the need for improved communication between owners, authorities and veterinarians. PMID:23130576

  15. Performance of a plastic-wrapped composting system for biosecure emergency disposal of disease-related swine mortalities.

    Science.gov (United States)

    Glanville, Thomas D; Ahn, Heekwon; Akdeniz, Neslihan; Crawford, Benjamin P; Koziel, Jacek A

    2016-02-01

    A passively-ventilated plastic-wrapped composting system initially developed for biosecure disposal of poultry mortalities caused by avian influenza was adapted and tested to assess its potential as an emergency disposal option for disease-related swine mortalities. Fresh air was supplied through perforated plastic tubing routed through the base of the compost pile. The combined air inlet and top vent area is ⩽∼1% of the gas exchange surface of a conventional uncovered windrow. Parameters evaluated included: (1) spatial and temporal variations in matrix moisture content (m.c.), leachate production, and matrix O2 concentrations; (2) extent of soft tissue decomposition; and (3) internal temperature and the success rate in achieving USEPA time/temperature (T) criteria for pathogen reduction. Six envelope materials (wood shavings, corn silage, ground cornstalks, ground oat straw, ground soybean straw, or ground alfalfa hay) and two initial m.c.'s (15-30% w.b. for materials stored indoors, and 45-65% w.b. to simulate materials exposed to precipitation) were tested to determine their effect on performance parameters (1-3). Results of triple-replicated field trials showed that the composting system did not accumulate moisture despite the 150kg carcass water load (65% of 225kg total carcass mass) released during decomposition. Mean compost m.c. in the carcass layer declined by ∼7 percentage points during 8-week trials, and a leachate accumulation was rare. Matrix O2 concentrations for all materials other than silage were ⩾10% using the equivalent of 2m inlet/vent spacing. In silage O2 dropped below 5% in some cases even when 0.5m inlet/vent spacing was used. Eight week soft tissue decomposition ranged from 87% in cornstalks to 72% in silage. Success rates for achievement of USEPA Class B time/temperature criteria ranged from 91% for silage to 33-57% for other materials. Companion laboratory biodegradation studies suggest that Class B success rates can be improved

  16. Swedish Farmers' Opinions about Biosecurity and Their Intention to Make Professionals Use Clean Protective Clothing When Entering the Stable.

    Science.gov (United States)

    Nöremark, Maria; Sternberg Lewerin, Susanna; Ernholm, Linda; Frössling, Jenny

    2016-01-01

    The study was part of a series of studies aiming to increase knowledge about spread and prevention of livestock diseases in Sweden. A specific biosecurity behavior, i.e., making professionals (e.g., veterinarian, repairman, livestock transporter) wear clean protective clothing when entering the stables was investigated through focus groups and a questionnaire survey. This behavior was seen as a proxy for other biosecurity behaviors. As part of questionnaire development, three focus group discussions with a total of 11 participating livestock farmers were held. The questionnaire was based on the model of Theory of Planned Behavior. Response was received from 2,081 farmers. In the focus groups, farmers expressed a willingness to provide visitors with clean protective clothing. However, some had experienced difficulties in making veterinarians use protective clothing, and mentioned a reluctance to correct their veterinarians. The participants mostly focused on diseases regulated by control programs, especially Salmonella. In parts, participants were well informed but some showed a lack of knowledge concerning routes of disease spread. They also mentioned external factors that made them deviate from biosecurity recommendations. Farmers called for biosecurity advice with focus on cost-benefit return. Among survey respondents, the intention to make visitors wear protective clothing was moderate. Analysis of underlying elements showed that a majority of farmers (88%) had a neutral attitude, i.e., they were neither in favor nor against this behavior. Measures of subjective norm indicated a varying degree of social pressure among respondents. However, the majority (63%) indicated a strong behavioral control, thus suggesting that they could make visitors use protective clothing if they wanted to. Although most farmers (84%) indicated a strong willingness to comply with the opinion of their veterinarians in biosecurity matters, 30% replied that their farm veterinarian is

  17. Expert Opinion on the Perceived Effectiveness and Importance of On-Farm Biosecurity Measures for Cattle and Swine Farms in Switzerland.

    Science.gov (United States)

    Kuster, Karin; Cousin, Marie-Eve; Jemmi, Thomas; Schüpbach-Regula, Gertraud; Magouras, Ioannis

    2015-01-01

    Biosecurity is crucial for safeguarding livestock from infectious diseases. Despite the plethora of biosecurity recommendations, published scientific evidence on the effectiveness of individual biosecurity measures is limited. The objective of this study was to assess the perception of Swiss experts about the effectiveness and importance of individual on-farm biosecurity measures for cattle and swine farms (31 and 30 measures, respectively). Using a modified Delphi method, 16 Swiss livestock disease specialists (8 for each species) were interviewed. The experts were asked to rank biosecurity measures that were written on cards, by allocating a score from 0 (lowest) to 5 (highest). Experts ranked biosecurity measures based on their importance related to Swiss legislation, feasibility, as well as the effort required for implementation and the benefit of each biosecurity measure. The experts also ranked biosecurity measures based on their effectiveness in preventing an infectious agent from entering and spreading on a farm, solely based on transmission characteristics of specific pathogens. The pathogens considered by cattle experts were those causing Bluetongue (BT), Bovine Viral Diarrhea (BVD), Foot and Mouth Disease (FMD) and Infectious Bovine Rhinotracheitis (IBR). Swine experts expressed their opinion on the pathogens causing African Swine Fever (ASF), Enzootic Pneumonia (EP), Porcine Reproductive and Respiratory Syndrome (PRRS), as well as FMD. For cattle farms, biosecurity measures that improve disease awareness of farmers were ranked as both most important and most effective. For swine farms, the most important and effective measures identified were those related to animal movements. Among all single measures evaluated, education of farmers was perceived by the experts to be the most important and effective for protecting both Swiss cattle and swine farms from disease. The findings of this study provide an important basis for recommendation to farmers and

  18. Expert Opinion on the Perceived Effectiveness and Importance of On-Farm Biosecurity Measures for Cattle and Swine Farms in Switzerland

    Science.gov (United States)

    Kuster, Karin; Cousin, Marie-Eve; Jemmi, Thomas; Schüpbach-Regula, Gertraud; Magouras, Ioannis

    2015-01-01

    Biosecurity is crucial for safeguarding livestock from infectious diseases. Despite the plethora of biosecurity recommendations, published scientific evidence on the effectiveness of individual biosecurity measures is limited. The objective of this study was to assess the perception of Swiss experts about the effectiveness and importance of individual on-farm biosecurity measures for cattle and swine farms (31 and 30 measures, respectively). Using a modified Delphi method, 16 Swiss livestock disease specialists (8 for each species) were interviewed. The experts were asked to rank biosecurity measures that were written on cards, by allocating a score from 0 (lowest) to 5 (highest). Experts ranked biosecurity measures based on their importance related to Swiss legislation, feasibility, as well as the effort required for implementation and the benefit of each biosecurity measure. The experts also ranked biosecurity measures based on their effectiveness in preventing an infectious agent from entering and spreading on a farm, solely based on transmission characteristics of specific pathogens. The pathogens considered by cattle experts were those causing Bluetongue (BT), Bovine Viral Diarrhea (BVD), Foot and Mouth Disease (FMD) and Infectious Bovine Rhinotracheitis (IBR). Swine experts expressed their opinion on the pathogens causing African Swine Fever (ASF), Enzootic Pneumonia (EP), Porcine Reproductive and Respiratory Syndrome (PRRS), as well as FMD. For cattle farms, biosecurity measures that improve disease awareness of farmers were ranked as both most important and most effective. For swine farms, the most important and effective measures identified were those related to animal movements. Among all single measures evaluated, education of farmers was perceived by the experts to be the most important and effective for protecting both Swiss cattle and swine farms from disease. The findings of this study provide an important basis for recommendation to farmers and

  19. Expert Opinion on the Perceived Effectiveness and Importance of On-Farm Biosecurity Measures for Cattle and Swine Farms in Switzerland.

    Directory of Open Access Journals (Sweden)

    Karin Kuster

    Full Text Available Biosecurity is crucial for safeguarding livestock from infectious diseases. Despite the plethora of biosecurity recommendations, published scientific evidence on the effectiveness of individual biosecurity measures is limited. The objective of this study was to assess the perception of Swiss experts about the effectiveness and importance of individual on-farm biosecurity measures for cattle and swine farms (31 and 30 measures, respectively. Using a modified Delphi method, 16 Swiss livestock disease specialists (8 for each species were interviewed. The experts were asked to rank biosecurity measures that were written on cards, by allocating a score from 0 (lowest to 5 (highest. Experts ranked biosecurity measures based on their importance related to Swiss legislation, feasibility, as well as the effort required for implementation and the benefit of each biosecurity measure. The experts also ranked biosecurity measures based on their effectiveness in preventing an infectious agent from entering and spreading on a farm, solely based on transmission characteristics of specific pathogens. The pathogens considered by cattle experts were those causing Bluetongue (BT, Bovine Viral Diarrhea (BVD, Foot and Mouth Disease (FMD and Infectious Bovine Rhinotracheitis (IBR. Swine experts expressed their opinion on the pathogens causing African Swine Fever (ASF, Enzootic Pneumonia (EP, Porcine Reproductive and Respiratory Syndrome (PRRS, as well as FMD. For cattle farms, biosecurity measures that improve disease awareness of farmers were ranked as both most important and most effective. For swine farms, the most important and effective measures identified were those related to animal movements. Among all single measures evaluated, education of farmers was perceived by the experts to be the most important and effective for protecting both Swiss cattle and swine farms from disease. The findings of this study provide an important basis for recommendation to farmers

  20. On the outside looking in: redefining the role of analytical chemistry in the biosciences.

    Science.gov (United States)

    Hare, Dominic J; New, Elizabeth J

    2016-07-12

    Biomedical research has moved on from the study of the structure of organs, cells and organelles. Today, the key questions that must be addressed to understand the body in health and disease are related to fundamental biochemistry: the distribution and speciation of chemicals, the regulation of chemical reactions, and the control of chemical environments. To see advances in this field, it is essential for analytical chemists to actively engage in this process, from beginning to end. In this Feature Article, we review the progress that has been made towards gaining an understanding of the chemistry of the body, while commenting on the intrinsic disconnect between new innovations in the field of analytical chemistry and practical application within the biosciences. We identify the challenges that prevent chemists from making a greater impact in this field, and highlight key steps for moving forward.

  1. Googling your genes: personal genomics and the discourse of citizen bioscience in the network age

    Directory of Open Access Journals (Sweden)

    Marina Levina

    2010-03-01

    Full Text Available In this essay, I argue that the rise of personal genomics is technologically, economically, and most importantly, discursively tied to the rise of network subjectivity, an imperative of which is an understanding of self as always already a subject in the network. I illustrate how personal genomics takes full advantage of social media technology and network subjectivity to advertise a new way of doing research that emphasizes collaboration between researchers and its members. Sharing one’s genetic information is considered to be an act of citizenship, precisely because it is good for the network. Here members are encouraged to think of themselves as dividuals, or nodes, in the network and their actions acquire value based on that imperative. Therefore, citizen bioscience is intricately tied, both in discourse and practices, to the growth of the network in the age of new media.

  2. Scientific Reports of Plasma Medicine and its Mechanism for Therapy in Plasma Bioscience Research Center

    Science.gov (United States)

    Choi, Eun Ha

    2015-09-01

    Scientific reports of plasma medicine and its basic mechanism for therapy will be introduced, especially, performed in Plasma Bioscience Research Center, Korea. We have investigated enhanced anticancer effect of monocytes and macrophages activated by nonthermal plasma which act as immune-modulator on these immune cells. Further, we investigated the action of the nanosecond pulsed plasma activated media (NPPAM) on the lung cancer cells and its DNA oxidation pathway. We observed OD induced apoptosis on melanocytes G361 cancer cells through DNA damage signaling cascade. We also studied DNA oxidation by extracting DNA from treated cancer cell and analyzed the effects of OD/OH/D2O2/H2O2 on protein modification and oxidation. Additionally, we attempted molecular docking approaches to check the action of D2O2 on the apoptosis related genes.

  3. On the outside looking in: redefining the role of analytical chemistry in the biosciences.

    Science.gov (United States)

    Hare, Dominic J; New, Elizabeth J

    2016-07-12

    Biomedical research has moved on from the study of the structure of organs, cells and organelles. Today, the key questions that must be addressed to understand the body in health and disease are related to fundamental biochemistry: the distribution and speciation of chemicals, the regulation of chemical reactions, and the control of chemical environments. To see advances in this field, it is essential for analytical chemists to actively engage in this process, from beginning to end. In this Feature Article, we review the progress that has been made towards gaining an understanding of the chemistry of the body, while commenting on the intrinsic disconnect between new innovations in the field of analytical chemistry and practical application within the biosciences. We identify the challenges that prevent chemists from making a greater impact in this field, and highlight key steps for moving forward. PMID:26898242

  4. Laboratory directed research and development. FY 1995 progress report

    Energy Technology Data Exchange (ETDEWEB)

    Vigil, J.; Prono, J. [comps.

    1996-03-01

    This document presents an overview of Laboratory Directed Research and Development Programs at Los Alamos. The nine technical disciplines in which research is described include materials, engineering and base technologies, plasma, fluids, and particle beams, chemistry, mathematics and computational science, atmic and molecular physics, geoscience, space science, and astrophysics, nuclear and particle physics, and biosciences. Brief descriptions are provided in the above programs.

  5. Production of Doctorates in the Biosciences, 1975-1980: An Experimental Forecast. Higher Education Panel Reports, No. 34.

    Science.gov (United States)

    Atelsek, Frank J.; Gomberg, Irene L.

    A survey was undertaken in 1976 to obtain short-term estimates of doctorate production directly from the heads of the science departments involved. These biosciences departments were surveyed in the 235 member institutions of the Higher Education Panel that grant doctorates: anatomy, biochemistry, biology, biometry/biostatistics/biomathematics,…

  6. Effect of A-Level Subject Choice and Entry Tariff on Final Degree and Level 1 Performance in Biosciences

    Science.gov (United States)

    King, Nicola C.; Aves, Stephen J.

    2012-01-01

    Following the publication of the higher education white paper increasing entry tariff and widening participation have become even more important issues for universities. This report examines the relationship between entry tariff and undergraduate achievement in Biosciences at the University of Exeter. We show that, whilst there is a significant…

  7. Use of stakeholder analysis to inform risk communication and extension strategies for improved biosecurity amongst small-scale pig producers.

    Science.gov (United States)

    Hernández-Jover, M; Gilmour, J; Schembri, N; Sysak, T; Holyoake, P K; Beilin, R; Toribio, J-A L M L

    2012-05-01

    Extension and communication needs amongst small-scale pig producers, described as pig producers with less than 100 sows, have been previously identified. These producers, who are believed to pose a biosecurity risk to commercial livestock industries, are characterized by a lack of formal networks, mistrust of authorities, poor disease reporting behaviour and motivational diversity, and reliance on other producers, veterinarians and family for pig health and production advice. This paper applies stakeholder identification and analysis tools to determine stakeholders' influence and interest on pig producers' practices. Findings can inform a risk communication process and the development of an extension framework to increase producers' engagement with industry and their compliance with biosecurity standards and legislation in Australia. The process included identification of stakeholders, their issues of concerns regarding small-scale pig producers and biosecurity and their influence and interest in each of these issues. This exercise identified the capacity of different stakeholders to influence the outcomes for each issue and assessed their success or failure to do so. The disconnection identified between the level of interest and influence suggests that government and industry need to work with the small-scale pig producers and with those who have the capacity to influence them. Successful biosecurity risk management will depend on shared responsibility and building trust amongst stakeholders. Flow-on effects may include legitimating the importance of reporting and compliance systems and the co-management of risk. Compliance of small-scale pig producers with biosecurity industry standards and legislation will reduce the risks of entry and spread of exotic diseases in Australia.

  8. Live pig markets in eastern Indonesia: Trader characteristics, biosecurity and implications for disease spread.

    Science.gov (United States)

    Leslie, Edwina E C; Geong, Maria; Abdurrahman, Muktasam; Ward, Michael P; Toribio, Jenny-Ann L M L

    2016-03-01

    Classical swine fever has been negatively impacting pig production in Nusa Tenggara Timur province in eastern Indonesia since its introduction in the 1990s, with live market trade contributing to disease spread. To understand market trader knowledge and practices regarding pig management, biosecurity, pig movements and pig health (specifically CSF), a repeated survey was conducted with pig sellers and pig buyers at 9 market sites across West Timor and the islands of Flores and Sumba. A total of 292 sellers and 281 buyers were interviewed in 2009 during two periods (rounds), a high-demand month (September) and a low-demand month (November). Information was collected via questionnaire. The majority of traders were male (sellers: 89%; buyers: 87%) with the highest level of completed education being primary school (sellers: 48%; buyers: 41%). The primary occupation of most respondents was farming: 90% of sellers and 87% of buyers were smallholder pig farmers and tended to sell their own home-raised pigs at market (52%). Pigs were sold for monetary gain either for primary (52%) or extra income (44%). Markets tended to be selected based on a good reputation (62%), a location close to residence (62%) and having the desired pig type (59%). Pig sales through markets were reported to be highest from August to October with 31% of sellers trading pigs at two or more markets. Prices at market were significantly higher on Sumba compared to West Timor and cross-bred pigs were significantly more expensive than indigenous pigs. Understanding of CSF and biosecurity was limited: 85% of sellers and 83% of buyers had no prior knowledge of CSF. Fifty-four percent of sellers reported no use of any biosecurity practices at market. Most respondents (88%) were able to recognise at least one clinical sign of a sick pig. Informal pig movements were also identified: 18% of pig buyers purchased pigs directly from other farmers. This study has provided baseline information on market trader

  9. Local poultry biosecurity risks to highly pathogenic avian influenza in Kaduna State, Nigeria.

    Science.gov (United States)

    Paul, Abdu A; Assam, Assam; Ndang, Tabe-Ntui L

    2013-01-01

    The study appraised local poultry biosecurity risks to highly pathogenic avian influenza by assessing farmers' knowledge, beliefs and poultry practices using a standard questionnaire. Farmers' knowledge on transmission and prevention was high but low on disease recognition. Radio was ineffective at informing Islamic educated farmers. Extensive knowledge on transmission and protection did not result in behavioural change as farmers engaged in risky practices of selling, eating or medicating infected poultry and not reporting poultry death. Islamic educated farmers do not believe highly pathogenic avian influenza is a serious and preventable disease. Women are more likely to self medicate when experiencing influenza-like illness. Audio-visual aids would improve avian influenza recognition while involvement of community leaders would enhance disease reporting. Outbreak of highly pathogenic avian influenza in local poultry in Nigeria would follow a similar pattern in Southeast Asia if the risk perception among farmers is not urgently articulated.

  10. 78 FR 33429 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2013-06-04

    ... Laboratory Baptist Medical Center). Clinical Reference Lab, 8433 Quivira Road, Lenexa, KS 66215-2802, 800...-631-4600/877-642-2216, (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science...). The Mandatory Guidelines were first published in the Federal Register on April 11, 1988 (53 FR...

  11. 76 FR 68201 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2011-11-03

    ....) Clinical Reference Lab, 8433 Quivira Road, Lenexa, KS 66215-2802, (800) 445-6917. Doctors Laboratory, Inc...-4600/(877) 642-2216, (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science...). The Mandatory Guidelines were first published in the Federal Register on April 11, 1988 (53 FR...

  12. 76 FR 75889 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2011-12-05

    ...). Clinical Reference Lab, 8433 Quivira Road, Lenexa, KS 66215-2802, (800) 445-6917. Doctors Laboratory, Inc...-4600/(877) 642-2216, (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science...). The Mandatory Guidelines were first published in the Federal Register on April 11, 1988 (53 FR...

  13. 77 FR 126 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2012-01-03

    ...) Clinical Reference Lab, 8433 Quivira Road, Lenexa, KS 66215-2802, (800) 445-6917. Doctors Laboratory, Inc...-4600/(877) 642-2216, (Formerly: SmithKline Beecham Clinical Laboratories; SmithKline Bio-Science...). The Mandatory Guidelines were first published in the Federal Register on April 11, 1988 (53 FR...

  14. Enhancing knowledge and awareness of biosecurity practices for control of African swine fever among smallholder pig farmers in four districts along the Kenya-Uganda border.

    Science.gov (United States)

    Nantima, Noelina; Davies, Jocelyn; Dione, Michel; Ocaido, Michael; Okoth, Edward; Mugisha, Anthony; Bishop, Richard

    2016-04-01

    A study was undertaken along the Kenya-Uganda border in four districts of Tororo and Busia (Uganda) and Busia and Teso (Kenya) to understand smallholder farmers' knowledge, practices and awareness of biosecurity measures. Information was collected by administering questionnaires to 645 randomly selected pig households in the study area. In addition, focus group discussions were carried out in 12 villages involving 248 people using a standardized list of questions. The outcome suggested that there was a very low level of awareness of biosecurity practices amongst smallholder farmers. We conclude that adoption of specific biosecurity practices by smallholder farmers is feasible but requires institutional support. There is a clear requirement for government authorities to sensitize farmers using approaches that allow active participation of farmers in the design, planning and implementation of biosecurity practices to enable enhanced adoption. PMID:26922740

  15. Laboratory-directed research and development

    International Nuclear Information System (INIS)

    This report summarizes progress from the Laboratory-Directed Research and Development (LDRD) program during fiscal year 1991. In addition to a programmatic and financial overview, the report includes progress reports from 230 individual R ampersand D projects in 9 scientific categories: atomic and molecular physics; biosciences; chemistry; engineering and base technologies; geosciences; space sciences, and astrophysics; materials sciences; mathematics and computational sciences; nuclear and particle physics; and plasmas, fluids, and particle beams

  16. Isotopes and trace elements as natal origin markers of Helicoverpa armigera--an experimental model for biosecurity pests.

    Directory of Open Access Journals (Sweden)

    Peter W Holder

    Full Text Available Protecting a nation's primary production sector and natural estate is heavily dependent on the ability to determine the risk presented by incursions of exotic insect species. Identifying the geographic origin of such biosecurity breaches can be crucial in determining this risk and directing the appropriate operational responses and eradication campaigns, as well as ascertaining incursion pathways. Reading natural abundance biogeochemical markers using mass spectrometry is a powerful tool for tracing ecological pathways as well as provenance determination of commercial products and items of forensic interest. However, application of these methods to trace insects has been underutilised to date and our understanding in this field is still in a phase of basic development. In addition, biogeochemical markers have never been considered in the atypical situation of a biosecurity incursion, where sample sizes are often small, and of unknown geographic origin and plant host. These constraints effectively confound the interpretation of the one or two isotope geo-location markers systems that are currently used, which are therefore unlikely to achieve the level of provenance resolution required in biosecurity interceptions. Here, a novel approach is taken to evaluate the potential for provenance resolution of insect samples through multiple biogeochemical markers. The international pest, Helicoverpa armigera, has been used as a model species to assess the validity of using naturally occurring δ2H, 87Sr/86Sr, 207Pb/206Pb and 208Pb/206Pb isotope ratios and trace element concentration signatures from single moth specimens for regional assignment to natal origin. None of the biogeochemical markers selected were individually able to separate moths from the different experimental regions (150-3000 km apart. Conversely, using multivariate analysis, the region of origin was correctly identified for approximately 75% of individual H. armigera samples. The

  17. Isotopes and Trace Elements as Natal Origin Markers of Helicoverpa armigera – An Experimental Model for Biosecurity Pests

    Science.gov (United States)

    Holder, Peter W.; Armstrong, Karen; Van Hale, Robert; Millet, Marc-Alban; Frew, Russell; Clough, Timothy J.; Baker, Joel A.

    2014-01-01

    Protecting a nation's primary production sector and natural estate is heavily dependent on the ability to determine the risk presented by incursions of exotic insect species. Identifying the geographic origin of such biosecurity breaches can be crucial in determining this risk and directing the appropriate operational responses and eradication campaigns, as well as ascertaining incursion pathways. Reading natural abundance biogeochemical markers using mass spectrometry is a powerful tool for tracing ecological pathways as well as provenance determination of commercial products and items of forensic interest. However, application of these methods to trace insects has been underutilised to date and our understanding in this field is still in a phase of basic development. In addition, biogeochemical markers have never been considered in the atypical situation of a biosecurity incursion, where sample sizes are often small, and of unknown geographic origin and plant host. These constraints effectively confound the interpretation of the one or two isotope geo-location markers systems that are currently used, which are therefore unlikely to achieve the level of provenance resolution required in biosecurity interceptions. Here, a novel approach is taken to evaluate the potential for provenance resolution of insect samples through multiple biogeochemical markers. The international pest, Helicoverpa armigera, has been used as a model species to assess the validity of using naturally occurring δ2H, 87Sr/86Sr, 207Pb/206Pb and 208Pb/206Pb isotope ratios and trace element concentration signatures from single moth specimens for regional assignment to natal origin. None of the biogeochemical markers selected were individually able to separate moths from the different experimental regions (150–3000 km apart). Conversely, using multivariate analysis, the region of origin was correctly identified for approximately 75% of individual H. armigera samples. The geographic resolution

  18. Assessment, Development and Implementation of Training Materials for Food Defense/Safety, Biosecurity, and Traceability within the Catfish Industry

    OpenAIRE

    Hood, Anna F.; Williams, J. Byron; Crist, Courtney

    2012-01-01

    The objective of this research and subsequent training sessions was to assess food defense in the catfish industry, promote awareness and educate catfish farmers and processors on the principles of food defense, biosecurity and traceability of agricultural commodities and ingredients used in human food production. In the catfish processing chain, preliminary investigations have indicated that there are areas throughout production, processing and distribution that are susceptible to potential ...

  19. Division of Energy Biosciences annual report and summaries of FY 1991 activities

    Energy Technology Data Exchange (ETDEWEB)

    1991-09-01

    As a component of the Department of Energy, the Energy Biosciences (EB) program of the Office of Basic Energy Sciences supports long-term research aimed at addressing energy-related problems utilizing biological systems. There are three main components of the EB program. The first, Primary Biological Energy Conversion, concentrates on research on plant and microbial photosynthesis, but also deals with plant growth control, stress reactions, and interaction with pathogens. The second, Bioconversion of Products, concentrates on utilization of the products of primary energy conversion. Specific examples include biosynthesis of potential fuels or chemicals, biodegradation of lignocellulose into potentially useful compounds, plant/microbe symbiosis, microbial methanogenesis and fermentation. The third main component of the EB program involves providing the basic research infrastructure to support future discoveries. The emphasis here is on investigation of basic genetic mechanisms, both in novel systems and extensively studied systems such as maize; development of critical databases, techniques, and instrumentation; and support of training in areas that are important but underpopulated. Brief descriptions of currently supported research projects are provided. 186 refs., 1 tab (MHB)

  20. Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

    Directory of Open Access Journals (Sweden)

    Carol Kilkenny

    2014-02-01

    Full Text Available In the last decade the number of bioscience journals has increased enormously, with many filling specialised niches reflecting new disciplines and technologies. The emergence of open-access journals has revolutionised the publication process, maximising the availability of research data. Nevertheless, a wealth of evidence shows that across many areas, the reporting of biomedical research is often inadequate, leading to the view that even if the science is sound, in many cases the publications themselves are not “fit for purpose”, meaning that incomplete reporting of relevant information effectively renders many publications of limited value as instruments to inform policy or clinical and scientific practice [1–21]. A recent review of clinical research showed that there is considerable cumulative waste of financial resources at all stages of the research process, including as a result of publications that are unusable due to poor reporting [22]. It is unlikely that this issue is confined to clinical research [2–14,16–20].

  1. Division of Energy Biosciences annual report and summaries of FY 1991 activities

    International Nuclear Information System (INIS)

    As a component of the Department of Energy, the Energy Biosciences (EB) program of the Office of Basic Energy Sciences supports long-term research aimed at addressing energy-related problems utilizing biological systems. There are three main components of the EB program. The first, Primary Biological Energy Conversion, concentrates on research on plant and microbial photosynthesis, but also deals with plant growth control, stress reactions, and interaction with pathogens. The second, Bioconversion of Products, concentrates on utilization of the products of primary energy conversion. Specific examples include biosynthesis of potential fuels or chemicals, biodegradation of lignocellulose into potentially useful compounds, plant/microbe symbiosis, microbial methanogenesis and fermentation. The third main component of the EB program involves providing the basic research infrastructure to support future discoveries. The emphasis here is on investigation of basic genetic mechanisms, both in novel systems and extensively studied systems such as maize; development of critical databases, techniques, and instrumentation; and support of training in areas that are important but underpopulated. Brief descriptions of currently supported research projects are provided. 186 refs., 1 tab

  2. Annual report and summaries of FY 1993 activities: Division of Energy Biosciences

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    The mission of the Energy Biosciences program is to generate fundamental information about plants and non-health related microorganisms that will constitute the base for new biotechnologies as well as supply information to improve usages of such organisms in their current form. The collective aims are totally consistent with the Department of Energy`s objectives of developing alternate energy sources, replacements for otherwise fossil energy derived products and providing critical fundamental information for the preservation and restoration of environmental conditions affected by energy related activities. The EB program takes full advantage of its organizational locale in the Office of Basic Energy Sciences to directly interact with such disciplines as Materials Sciences, Chemistry, Engineering and Geosciences to promote cross-disciplinary research and planning activities. One of the major specific objectives of the EB program is to probe the enormous capabilities of the specified organisms to carry out biochemical conversions. The limitation to realization of entirely new products and processes via biotechnology is the lack of basic understanding of natural processes. Such knowledge will then afford the advantage of developing procedures to the benefit of people and their society in providing new products along with providing new employment possibilities. This document consists of abstracts of projects supported in FY 1993.

  3. 生物安全是国家战略必需的生命工程%Biosecurity is a living-project essential to national strategies

    Institute of Scientific and Technical Information of China (English)

    郑涛; 田德桥; 祖正虎; 朱联辉; 黄培堂; 沈倍奋

    2014-01-01

    该文通过对生物安全主要领域形势的分析,总结了生物安全有别于传统安全的3个典型特征,提出生物安全是国家的生命工程,有足够能力保障生物安全是成熟大国、世界强国的必要条件的观点。通过分析了美国发展生物安全的国家战略特征和基本做法,指出美国已经从国家层面建立了一套能力发展目标明确、政府机构职责清晰、法规战略相互衔接的生物安全发展规划与路线图。我国生物安全建设步入到了十字路口,危机与机遇并存,亟需确立生物安全的国家战略地位。%Based on situation assessment of the core areas of biosecurity , this paper summarizes three typical features of biosecurity that make it different from traditional safety , abd proposes that biosecurity be regarded as a living-project of a country .A mature and powerful country has to possess sufficient capacity to ensure biosecurity .This study also analyzes the national biosecurity strategyies and practices of the United States ,which has established a national-level capacity building strategy and roadmap with clear objectives ,specified the responsibilities of each federal agency , and regulations linked up with strategic planning .Biosecurity in China is at the crossroads where crisis coexists with opportunity , making it urgent to establish the national biosecurity strategy .

  4. Control strategies against Campylobacter at the poultry production level: biosecurity measures, feed additives and vaccination.

    Science.gov (United States)

    Meunier, M; Guyard-Nicodème, M; Dory, D; Chemaly, M

    2016-05-01

    Campylobacteriosis is the most prevalent bacterial foodborne gastroenteritis affecting humans in the European Union, and ranks second in the United States only behind salmonellosis. In Europe, there are about nine million cases of campylobacteriosis every year, making the disease a major public health issue. Human cases are mainly caused by the zoonotic pathogen Campylobacter jejuni. The main source of contamination is handling or consumption of poultry meat. Poultry constitutes the main reservoir of Campylobacter, substantial quantities of which are found in the intestines following rapid, intense colonization. Reducing Campylobacter levels in the poultry chain would decrease the incidence of human campylobacteriosis. As primary production is a crucial step in Campylobacter poultry contamination, controlling the infection at this level could impact the following links along the food chain (slaughter, retail and consumption). This review describes the control strategies implemented during the past few decades in primary poultry production, including the most recent studies. In fact, the implementation of biosecurity and hygiene measures is described, as well as the immune strategy with passive immunization and vaccination trials and the nutritional strategy with the administration of organic and fatty acids, essential oil and plant-derived compound, probiotics, bacteriocins and bacteriophages. PMID:26541243

  5. Welfare and biosecurity standards for dairy cow and pig farms: Cattle and swine rearing conditions

    Directory of Open Access Journals (Sweden)

    Hristov Slavča

    2009-01-01

    Full Text Available In this paper the essential elements concerning cattle and swine rearing and growing conditions were given in order to establish welfare and biosecurity standards. These elements were formed according to detailed annual investigations on 11 cattle and 5 swine farms and include relevant spatial, microclimate and hygienic conditions. In order to establish welfare standards, certain spatial conditions have higher importance, such as correct construction and maintenance of beds, pens and yards, and type and quality of materials used to build beds and walls. It is necessary to enable movement of animals in stables and yards as basic physiological and ethologic needs, according to latest scientific data. Also, optimal temperature, relative humidity and air velocity insuring have to be considered, as well as quality ventilation in order to establish and preserve optimal microclimate conditions. Also, it must be pointed out that hygiene maintenance of stable surfaces and animal bodies on a regular bases is essential. Basic principles and criteria for welfare level assessment are given in this paper. According to results obtained in previous investigations, special attention is given to possibilities to correct rearing and growing conditions in cattle and swine farms in our country. .

  6. Embryo transfer: a comparative biosecurity advantage in international movements of germplasm.

    Science.gov (United States)

    Thibier, M

    2011-04-01

    This paper uses cattle as a model to provide an overview of the hazards involved in the transfer of in vivo-derived and in vitro-produced embryos. While scientific studies in recent decades have led to the identification of pathogens that may be associated with both in vivo- and in vitro-derived embryos, those studies have also been the basis of appropriate disease control measures to reduce the risks to a negligible level. These disease control measures have been identified and assessed by the International Embryo Transfer Society's (lETS) Health and Safety Advisory Committee, the expert body that advises the World Organisation for Animal Health (OIE) on matters related to the safety of embryo transfer. Through the OIE's processes for developing and adopting international standards, the disease control measures identified by the IETS have been incorporated into the Terrestrial Animal Health Code. The basic principles rely on the crucial ethical roles of the embryo collection team and embryo transfer team, under the leadership of approved veterinarians. Decades of experience, with nearly 10 million embryos transferred, have demonstrated the very significant biosecurity advantage that embryo transfer technology has when moving germplasm internationally, provided that the international standards developed by the IETS and adopted by the OIE are strictly followed. PMID:21809763

  7. A business case for on-site generation: The BD biosciences pharmingen project

    Energy Technology Data Exchange (ETDEWEB)

    Firestone, Ryan; Creighton, Charles; Bailey, Owen; Marnay, Chris; Stadler, Michael

    2003-09-01

    Deregulation is haltingly changing the United States electricity markets. The resulting uncertainty and/or rising energy costs can be hedged by generating electricity on-site and other benefits, such as use of otherwise wasted heat, can be captured. The Public Utility Regulatory Policy Act (PURPA) of 1978 first invited relatively small-scale generators ({ge} 1 MW) into the electricity market. The advent of efficient and reliable small scale and renewable equipment has spurred an industry that has, in recent years, made even smaller (business scale) electricity generation an economically viable option for some consumers. On-site energy capture and/or conversion, known as distributed energy resources (DER), offers consumers many benefits, such as economic savings and price predictability, improved reliability, control over power quality, and emissions reductions. Despite these benefits, DER adoption can be a daunting move to a customer accustomed to simply paying a monthly utility bill. San Diego is in many ways an attractive location for DER development: It has high electricity prices typical of California and a moderate climate i.e. energy loads are consistent throughout the year. Additionally, the price shock to San Diego Gas and Electric (SDG&E) customers during the summer of 2000 has interested many in alternatives to electricity price vulnerability. This report examines the business case for DER at the San Diego biotechnology supply company, BD Biosciences Pharmingen, which considered DER for a building with 200-300 kW base-load, much of which accommodates the refrigerators required to maintain chemicals. Because of the Mediterranean climate of the San Diego area and the high rate of air changes required due to on-site use of chemicals, modest space heating is required throughout the year. Employees work in the building during normal weekday business hours, and daily peak loads are typically about 500 kW.

  8. SBBN 2010: 7. Congress of the Brazilian Society of Nuclear Biosciences. Radiations in biosciences: advances and trends; SBBN 2010: 7. Congresso da Sociedade Brasileira de Biociencias Nucleares. Radiacoes em biociencias: avancos e perspectivas

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    Advance and new perspectives related to the use of ionizing and no ionizing radiations in nuclear biosciences are presented. Multidisciplinary approach, including radiopharmacy, radioprotection and dosimetry, cytogenetic, biosafety, radioecology, environmental toxicology are studied. Topics of Nuclear medicine, radiotherapy and image diagnosis, such as computerized tomography, PET scan, phantoms, biomedical radiography, are reported. Use of radioisotopes, evaluation of radiation dose rates, radiation dose distribution, radiation monitoring is considered. Environmental impact of radiation are also in human beings, animals and for several purposes are analyzed. (MAC)

  9. A Pilot Evaluation of an Online Tool Designed to Aid Development of Basic Laboratory Skills

    Science.gov (United States)

    Booth, Paula; Kebede-Westhead, Elizabeth; Heaney, Rose; Henderson-Begg, Stephanie K.

    2010-01-01

    A pilot study was conducted using a cohort of 18 students, studying for their Bioscience Masters, and carrying out project work throughout the summer. On arrival for a laboratory class the students were asked to complete a baseline confidence log and answer a knowledge quiz. The confidence log and quiz were developed from ideas suggested in Draper…

  10. A tale of three next generation sequencing platforms: comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq sequencers

    Directory of Open Access Journals (Sweden)

    Quail Michael A

    2012-07-01

    Full Text Available Abstract Background Next generation sequencing (NGS technology has revolutionized genomic and genetic research. The pace of change in this area is rapid with three major new sequencing platforms having been released in 2011: Ion Torrent’s PGM, Pacific Biosciences’ RS and the Illumina MiSeq. Here we compare the results obtained with those platforms to the performance of the Illumina HiSeq, the current market leader. In order to compare these platforms, and get sufficient coverage depth to allow meaningful analysis, we have sequenced a set of 4 microbial genomes with mean GC content ranging from 19.3 to 67.7%. Together, these represent a comprehensive range of genome content. Here we report our analysis of that sequence data in terms of coverage distribution, bias, GC distribution, variant detection and accuracy. Results Sequence generated by Ion Torrent, MiSeq and Pacific Biosciences technologies displays near perfect coverage behaviour on GC-rich, neutral and moderately AT-rich genomes, but a profound bias was observed upon sequencing the extremely AT-rich genome of Plasmodium falciparum on the PGM, resulting in no coverage for approximately 30% of the genome. We analysed the ability to call variants from each platform and found that we could call slightly more variants from Ion Torrent data compared to MiSeq data, but at the expense of a higher false positive rate. Variant calling from Pacific Biosciences data was possible but higher coverage depth was required. Context specific errors were observed in both PGM and MiSeq data, but not in that from the Pacific Biosciences platform. Conclusions All three fast turnaround sequencers evaluated here were able to generate usable sequence. However there are key differences between the quality of that data and the applications it will support.

  11. Towards a global barcode library for Lymantria (Lepidoptera: Lymantriinae tussock moths of biosecurity concern.

    Directory of Open Access Journals (Sweden)

    Jeremy R deWaard

    Full Text Available BACKGROUND: Detecting and controlling the movements of invasive species, such as insect pests, relies upon rapid and accurate species identification in order to initiate containment procedures by the appropriate authorities. Many species in the tussock moth genus Lymantria are significant forestry pests, including the gypsy moth Lymantria dispar L., and consequently have been a focus for the development of molecular diagnostic tools to assist in identifying species and source populations. In this study we expand the taxonomic and geographic coverage of the DNA barcode reference library, and further test the utility of this diagnostic method, both for species/subspecies assignment and for determination of geographic provenance of populations. METHODOLOGY/PRINCIPAL FINDINGS: Cytochrome oxidase I (COI barcodes were obtained from 518 individuals and 36 species of Lymantria, including sequences assembled and generated from previous studies, vouchered material in public collections, and intercepted specimens obtained from surveillance programs in Canada. A maximum likelihood tree was constructed, revealing high bootstrap support for 90% of species clusters. Bayesian species assignment was also tested, and resulted in correct assignment to species and subspecies in all instances. The performance of barcoding was also compared against the commonly employed NB restriction digest system (also based on COI; while the latter is informative for discriminating gypsy moth subspecies, COI barcode sequences provide greater resolution and generality by encompassing a greater number of haplotypes across all Lymantria species, none shared between species. CONCLUSIONS/SIGNIFICANCE: This study demonstrates the efficacy of DNA barcodes for diagnosing species of Lymantria and reinforces the view that the approach is an under-utilized resource with substantial potential for biosecurity and surveillance. Biomonitoring agencies currently employing the NB restriction

  12. Knowledge of poultry diseases, biosecurity and husbandry practices among stakeholders in poultry production in Kogi State, Nigeria

    Directory of Open Access Journals (Sweden)

    ON Ameji

    2012-12-01

    Full Text Available Commercial poultry production is low in Kogi State even before the advent of highly pathogenic avian influenza (HPAI H5N1 outbreak in Nigeria. The low level of poultry production has persisted long after the socio-economic impacts of HPAI had improved. A study was conducted among 94 poultry stakeholders in the state with the use of questionnaire to assess their knowledge of poultry diseases, biosecurity and poultry husbandry practices in six Local Government Areas of Kogi State. The findings showed that 60.0% of poultry production was rural while the rest were backyard (semi commercial poultry. About 64.7% of poultry kept were under extensive management with the commonest diseases seen under this management system being Newcastle disease (62.9%, Coccidiosis (52.3%, Fowl pox (46.9%, Gumboro disease (39.1% and Fowl typhoid (36.1%. Biosecurity was poor as 92.9% of respondents did not have footbath or hand wash disinfection; 70% would throw away poultry litter in the refuse dump; 12% would use the poultry litter as manure while 11% would sell out the litter. In addition, 64.7% of the poultry farmers obtained their rearing stock from the live bird market and other unknown sources while only 35.3% obtained theirs from the hatchery. The findings of this study showed that the low level of commercial poultry production in Kogi State might be due to the impacts of diseases and poor husbandry practices undertaken by the farmers. It is recommended that government should train poultry farmers on biosecurity, disease prevention and the adoption of modern husbandry practices suitable for the traditional poultry production system.

  13. 3 CFR 13486 - Executive Order 13486 of January 9, 2009. Strengthening Laboratory Biosecurity in the United States

    Science.gov (United States)

    2010-01-01

    ... Director of National Intelligence; (xii) the Director of the National Science Foundation; and (xiii) the... manner that seeks their individual advice and does not involve collective judgment or consensus advice...

  14. Biosecurity risks associated with current identification practices of producers trading live pigs at livestock sales.

    Science.gov (United States)

    Hernández-Jover, M; Schembri, N; Toribio, J-A L M L; Holyoake, P K

    2008-11-01

    Approximately 5% of pigs produced in Australia is believed to be traded at livestock sales. Interviews and focus group discussions were conducted with producers (106 and 30 producers, respectively), who traded pigs at livestock sales. The purpose of the study was to gather information on how producers identified their pigs in order to evaluate how these practices may impact the ability to trace pig movements in the event of an emergency animal disease outbreak or food safety hazard. Results were analyzed according to herd size (0 to 150 sows, 150+ sows) and location (peri-urban, regional) as prior studies suggested a higher biosecurity risk among smaller farms and due to perceptions that peri-urban farms pose additional risk. Most producers (91.5%) had less than 150 sows and a high proportion (70.8%) resided in regional areas compared with only 29.2% residing in peri-urban areas. A higher proportion of large-scale producers identified their pigs than small-scale producers. A third of small-scale producers reported not identifying breeding stock and most did not identify progeny. The most common forms of on-farm identification used were ear tags for breeding stock and ear notches for progeny. Producers identified breeding stock to assist with mating management and genetic improvement. Ear notches were used to determine the litter of origin of progeny. All large-scale producers owned a registered swine brand and used the official body tattoo for post-farm-gate identification. However, approximately 15% of small-scale producers did not own a registered swine brand, and an additional 8% did not identify their pigs post-farm-gate. Producers were satisfied with tattoos as a methodology for post-farm-gate identification of pigs and considered other methodologies cost-prohibitive. However, variations in the maintenance of the branding equipment, the type of ink used and the time of tattoo application in relation to the animal sale were highlighted during focus group

  15. Biosecurity risks associated with current identification practices of producers trading live pigs at livestock sales.

    Science.gov (United States)

    Hernández-Jover, M; Schembri, N; Toribio, J-A L M L; Holyoake, P K

    2008-11-01

    Approximately 5% of pigs produced in Australia is believed to be traded at livestock sales. Interviews and focus group discussions were conducted with producers (106 and 30 producers, respectively), who traded pigs at livestock sales. The purpose of the study was to gather information on how producers identified their pigs in order to evaluate how these practices may impact the ability to trace pig movements in the event of an emergency animal disease outbreak or food safety hazard. Results were analyzed according to herd size (0 to 150 sows, 150+ sows) and location (peri-urban, regional) as prior studies suggested a higher biosecurity risk among smaller farms and due to perceptions that peri-urban farms pose additional risk. Most producers (91.5%) had less than 150 sows and a high proportion (70.8%) resided in regional areas compared with only 29.2% residing in peri-urban areas. A higher proportion of large-scale producers identified their pigs than small-scale producers. A third of small-scale producers reported not identifying breeding stock and most did not identify progeny. The most common forms of on-farm identification used were ear tags for breeding stock and ear notches for progeny. Producers identified breeding stock to assist with mating management and genetic improvement. Ear notches were used to determine the litter of origin of progeny. All large-scale producers owned a registered swine brand and used the official body tattoo for post-farm-gate identification. However, approximately 15% of small-scale producers did not own a registered swine brand, and an additional 8% did not identify their pigs post-farm-gate. Producers were satisfied with tattoos as a methodology for post-farm-gate identification of pigs and considered other methodologies cost-prohibitive. However, variations in the maintenance of the branding equipment, the type of ink used and the time of tattoo application in relation to the animal sale were highlighted during focus group

  16. The Role Biomedical Science Laboratories Can Play in Improving Science Knowledge and Promoting First-Year Nursing Academic Success

    Science.gov (United States)

    Arneson, Pam

    2011-01-01

    The need for additional nursing and health care professionals is expected to increase dramatically over the next 20 years. With this in mind, students must have strong biomedical science knowledge to be competent in their field. Some studies have shown that participation in bioscience laboratories can enhance science knowledge. If this is true, an…

  17. Isotopes and trace elements as geo-location markers for biosecurity: determining the origin of exotic pests.

    Science.gov (United States)

    Holder, Peter W.; Armstrong, Karen; Clough, Tim; Frew, Russell; van Hale, Robert; Baker, Joel A.; Millet, Marc-Alban

    2010-05-01

    Background. The benefits of accurate point of origin discrimination in biosecurity include achieving appropriate operational responses in exotic pest eradication and post-border incursion campaigns, and identifying risk pathways. Reading natural abundance biogeochemical markers via mass spectrometry methods is a powerful tool for tracing ecological pathways and provenance determination of agricultural products and items of forensic interest. However, the application of these methods to trace insects - man's most damaging competitors - has been underutilised to date and our understanding in this field is still in a phase of basic development. Stable isotope ratio analyses using δ2H, δ13C have given spatial resolution in the monarch butterfly, single host system in eastern North America. Subsequently, the same method was employed in an attempt to determine the origin of important biosecurity pests in New Zealand. However, the results were contentious as the accuracy and limitations of the method in a biosecurity application were unknown. Further investigation has shown the value of existing invertebrate stable isotope geo-location methodology (i.e., using only two light elements) is tenuous in the biosecurity context, where the sample sizes are usually only one or two insects, and the specimens are generally polyphagous and accidentally introduced, and so from an unknown and unpredictable place, point in time and host: The spatial distribution of 2H in New Zealand may not be reliable over insect life-span time-scales; and fractional variables are un-quantified and potentially overwhelm any New Zealand signal. Further, the geo-location value of 13C is uncertain, especially for polyphagous insects. Research aims. The internationally distributed Helicoverpa armigera [Noctuidae] is being used to examine the processes fundamental to the location-to-plant-to-insect biogeochemical profile imprinting in phytophagous insects, including the turn over of elements in adult

  18. Accelerator mass spectrometry of ultra-small samples with applications in the biosciences

    Energy Technology Data Exchange (ETDEWEB)

    Salehpour, Mehran, E-mail: mehran.salehpour@physics.uu.se [Department of Physics and Astronomy, Ion Physics, PO Box 516, SE-751 20 Uppsala (Sweden); Hakansson, Karl; Possnert, Goeran [Department of Physics and Astronomy, Ion Physics, PO Box 516, SE-751 20 Uppsala (Sweden)

    2013-01-15

    An overview is presented covering the biological accelerator mass spectrometry activities at Uppsala University. The research utilizes the Uppsala University Tandem laboratory facilities, including a 5 MV Pelletron tandem accelerator and two stable isotope ratio mass spectrometers. In addition, a dedicated sample preparation laboratory for biological samples with natural activity is in use, as well as another laboratory specifically for {sup 14}C-labeled samples. A variety of ongoing projects are described and presented. Examples are: (1) Ultra-small sample AMS. We routinely analyze samples with masses in the 5-10 {mu}g C range. Data is presented regarding the sample preparation method, (2) bomb peak biological dating of ultra-small samples. A long term project is presented where purified and cell-specific DNA from various part of the human body including the heart and the brain are analyzed with the aim of extracting regeneration rate of the various human cells, (3) biological dating of various human biopsies, including atherosclerosis related plaques is presented. The average built up time of the surgically removed human carotid plaques have been measured and correlated to various data including the level of insulin in the human blood, and (4) In addition to standard microdosing type measurements using small pharmaceutical drugs, pre-clinical pharmacokinetic data from a macromolecular drug candidate are discussed.

  19. The impact of biosecurity and partial depopulation on Campylobacter prevalence in Irish broiler flocks with differing levels of hygiene and economic performance

    Directory of Open Access Journals (Sweden)

    Shaun Smith

    2016-05-01

    Full Text Available Background: Campylobacter jejuni is the leading bacterial food-borne pathogen within the European Union (EU, and poultry meat is the primary route for transmission to humans. Material and methods: This study examined the impact of partial depopulation (thinning, season, and farm performance (economic, hygiene, and biosecurity on Campylobacter prevalence in Irish broilers over a 13-month period. Ten caecal samples were taken per flock, for a total of 211 flocks from 23 farms during the duration of the study. Campylobacter was isolated and enumerated according to modified published ISO methods for veterinary samples. Biosecurity was evaluated through a questionnaire based on risk factors for Campylobacter identified in previous studies. Hygiene compliance was assessed from audit records taken over the course of 1 year. All information relating to biosecurity and hygiene was obtained directly from the processing company. This was done to ensure farmers were unaware they were being monitored for Campylobacter prevalence and prevent changes to their behaviour. Results and discussion: Farms with high performance were found to have significantly lower Campylobacter prevalence at first depopulation compared with low-performance farms across all seasons (P≤0.01. Peak Campylobacter levels were observed during the summer season at first thin in both the high- and low-performance groups. Campylobacter prevalence was found to increase to ≥85% in both high- and low-performance farms across all seasons at final depopulation, suggesting that Campylobacter was introduced during the first depopulation. On low-performance farms, four biosecurity interventions were found to significantly reduce the odds of a flock being Campylobacter positive (physical step-over barrier OR=0.17, house-specific footwear OR=0.13, absence of water body within 0.5 km OR=0.13, two or more broiler houses on a farm OR=0.16, compared with farms without these interventions. For high

  20. Life sciences payload definition and integration study. Volume 4: Appendix, costs, and data management requirements of the dedicated 30-day laboratory. [carry-on laboratory for Spacelab

    Science.gov (United States)

    1974-01-01

    The results of the updated 30-day life sciences dedicated laboratory scheduling and costing activities are documented, and the 'low cost' methodology used to establish individual equipment item costs is explained in terms of its allowances for equipment that is commerical off-the-shelf, modified commercial, and laboratory prototype; a method which significantly lowers program costs. The costs generated include estimates for non-recurring development, recurring production, and recurring operations costs. A cost for a biomedical emphasis laboratory and a Delta cost to provide a bioscience and technology laboratory were also generated. All cost reported are commensurate with the design and schedule definitions available.

  1. 1999 LDRD Laboratory Directed Research and Development

    Energy Technology Data Exchange (ETDEWEB)

    Rita Spencer; Kyle Wheeler

    2000-06-01

    This is the FY 1999 Progress Report for the Laboratory Directed Research and Development (LDRD) Program at Los Alamos National Laboratory. It gives an overview of the LDRD Program, summarizes work done on individual research projects, relates the projects to major Laboratory program sponsors, and provides an index to the principal investigators. Project summaries are grouped by their LDRD component: Competency Development, Program Development, and Individual Projects. Within each component, they are further grouped into nine technical categories: (1) materials science, (2) chemistry, (3) mathematics and computational science, (4) atomic, molecular, optical, and plasma physics, fluids, and particle beams, (5) engineering science, (6) instrumentation and diagnostics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) bioscience.

  2. Biosecurity and Vector Behaviour: Evaluating the Potential Threat Posed by Anglers and Canoeists as Pathways for the Spread of Invasive Non-Native Species and Pathogens

    Science.gov (United States)

    Anderson, Lucy G.; White, Piran C. L.; Stebbing, Paul D.; Stentiford, Grant D.; Dunn, Alison M.

    2014-01-01

    Invasive non-native species (INNS) endanger native biodiversity and are a major economic problem. The management of pathways to prevent their introduction and establishment is a key target in the Convention on Biological Diversity's Aichi biodiversity targets for 2020. Freshwater environments are particularly susceptible to invasions as they are exposed to multiple introduction pathways, including non-native fish stocking and the release of boat ballast water. Since many freshwater INNS and aquatic pathogens can survive for several days in damp environments, there is potential for transport between water catchments on the equipment used by recreational anglers and canoeists. To quantify this biosecurity risk, we conducted an online questionnaire with 960 anglers and 599 canoeists to investigate their locations of activity, equipment used, and how frequently equipment was cleaned and/or dried after use. Anglers were also asked about their use and disposal of live bait. Our results indicate that 64% of anglers and 78.5% of canoeists use their equipment/boat in more than one catchment within a fortnight, the survival time of many of the INNS and pathogens considered in this study and that 12% of anglers and 50% of canoeists do so without either cleaning or drying their kit between uses. Furthermore, 8% of anglers and 28% of canoeists had used their equipment overseas without cleaning or drying it after each use which could facilitate both the introduction and secondary spread of INNS in the UK. Our results provide a baseline against which to evaluate the effectiveness of future biosecurity awareness campaigns, and identify groups to target with biosecurity awareness information. Our results also indicate that the biosecurity practices of these groups must improve to reduce the likelihood of inadvertently spreading INNS and pathogens through these activities. PMID:24717714

  3. Real-time laboratory exercises to test contingency plans for classical swine fever: experiences from two national laboratories

    DEFF Research Database (Denmark)

    Koenen, K.; Uttenthal, Åse; Meindl-Böhmer, A.

    2007-01-01

    . It is essential that these plans are established during ‘peace-time’ and are reviewed regularly. This paper provides suggestions on how to perform laboratory exercises to test preparedness and describes the experiences of two national reference laboratories for CSF. The major lesson learnt was the importance...... contingency plans. These plans should ensure that in the event of an outbreak access to facilities, equipment, resources, trained personnel, and all other facilities needed for the rapid and efficient eradication of the outbreak is guaranteed, and that the procedures to follow are well rehearsed...... of a well-documented laboratory contingency plan. The major pitfalls encountered were shortage of space, difficulties in guaranteeing biosecurity and sufficient supplies of sterile equipment and consumables. The need for a standardised laboratory information management system, that is used by all those...

  4. Use of data mining techniques to investigate disease risk classification as a proxy for compromised biosecurity of cattle herds in Wales

    Directory of Open Access Journals (Sweden)

    Pfeiffer Dirk U

    2008-07-01

    Full Text Available Abstract Background Biosecurity is at the forefront of the fight against infectious diseases in animal populations. Few research studies have attempted to identify and quantify the effectiveness of biosecurity against disease introduction or presence in cattle farms and, when done, they have relied on the collection of on-farm data. Data on environmental, animal movement, demographic/husbandry systems and density disease determinants can be collated without requiring additional specific on-farm data collection activities, since they have already been collected for some other purposes. The aim of this study was to classify cattle herds according to their risk of disease presence as a proxy for compromised biosecurity in the cattle population of Wales in 2004 for risk-based surveillance purposes. Results Three data mining methods have been applied: logistic regression, classification trees and factor analysis. Using the cattle holding population in Wales, a holding was considered positive if at least bovine TB or one of the ten most frequently diagnosed infectious or transmissible non-notifiable diseases in England and Wales, according to the Veterinary Investigation Surveillance Report (VIDA had been diagnosed in 2004. High-risk holdings can be described as open large cattle herds located in high-density cattle areas with frequent movements off to many locations within Wales. Additional risks are associated with the holding being a dairy enterprise and with a large farming area. Conclusion This work has demonstrated the potential of mining various livestock-relevant databases to obtain generic criteria for individual cattle herd biosecurity risk classification. Despite the data and analytical constraints the described risk profiles are highly specific and present variable sensitivity depending on the model specifications. Risk profiling of farms provides a tool for designing targeted surveillance activities for endemic or emerging diseases

  5. Programmable bio-nano-chip system: a flexible point-of-care platform for bioscience and clinical measurements.

    Science.gov (United States)

    McRae, Michael P; Simmons, Glennon W; Wong, Jorge; Shadfan, Basil; Gopalkrishnan, Sanjiv; Christodoulides, Nicolaos; McDevitt, John T

    2015-10-21

    The development of integrated instrumentation for universal bioassay systems serves as a key goal for the lab-on-a-chip community. The programmable bio-nano-chip (p-BNC) system is a versatile multiplexed and multiclass chemical- and bio-sensing system for bioscience and clinical measurements. The system is comprised of two main components, a disposable cartridge and a portable analyzer. The customizable single-use plastic cartridges, which now can be manufactured in high volumes using injection molding, are designed for analytical performance, ease of use, reproducibility, and low cost. These labcard devices implement high surface area nano-structured biomarker capture elements that enable high performance signaling and are index-matched to real-world biological specimens. This detection modality, along with the convenience of on-chip fluid storage in blisters and self-contained waste, represents a standard process to digitize biological signatures at the point-of-care. A companion portable analyzer prototype has been developed to integrate fluid motivation, optical detection, and automated data analysis, and it serves as the human interface for complete assay automation. In this report, we provide a systems-level perspective of the p-BNC universal biosensing platform with an emphasis on flow control, device integration, and automation. To demonstrate the flexibility of the p-BNC, we distinguish diseased and non-case patients across three significant disease applications: prostate cancer, ovarian cancer, and acute myocardial infarction. Progress towards developing a rapid 7 minute myoglobin assay is presented using the fully automated p-BNC system.

  6. Programmable bio-nano-chip system: a flexible point-of-care platform for bioscience and clinical measurements.

    Science.gov (United States)

    McRae, Michael P; Simmons, Glennon W; Wong, Jorge; Shadfan, Basil; Gopalkrishnan, Sanjiv; Christodoulides, Nicolaos; McDevitt, John T

    2015-10-21

    The development of integrated instrumentation for universal bioassay systems serves as a key goal for the lab-on-a-chip community. The programmable bio-nano-chip (p-BNC) system is a versatile multiplexed and multiclass chemical- and bio-sensing system for bioscience and clinical measurements. The system is comprised of two main components, a disposable cartridge and a portable analyzer. The customizable single-use plastic cartridges, which now can be manufactured in high volumes using injection molding, are designed for analytical performance, ease of use, reproducibility, and low cost. These labcard devices implement high surface area nano-structured biomarker capture elements that enable high performance signaling and are index-matched to real-world biological specimens. This detection modality, along with the convenience of on-chip fluid storage in blisters and self-contained waste, represents a standard process to digitize biological signatures at the point-of-care. A companion portable analyzer prototype has been developed to integrate fluid motivation, optical detection, and automated data analysis, and it serves as the human interface for complete assay automation. In this report, we provide a systems-level perspective of the p-BNC universal biosensing platform with an emphasis on flow control, device integration, and automation. To demonstrate the flexibility of the p-BNC, we distinguish diseased and non-case patients across three significant disease applications: prostate cancer, ovarian cancer, and acute myocardial infarction. Progress towards developing a rapid 7 minute myoglobin assay is presented using the fully automated p-BNC system. PMID:26308851

  7. Laboratory design for high-performance electron microscopy

    Energy Technology Data Exchange (ETDEWEB)

    O' Keefe, Michael A.; Turner, John H.; Hetherington, Crispin J.D.; Cullis, A.G.; Carragher, Bridget; Jenkins, Ron; Milgrim, Julie; Milligan,Ronald A.; Potter, Clinton S.; Allard, Lawrence F.; Blom, Douglas A.; Degenhardt, Lynn; Sides, William H.

    2004-04-23

    Proliferation of electron microscopes with field emission guns, imaging filters and hardware spherical aberration correctors (giving higher spatial and energy resolution) has resulted in the need to construct special laboratories. As resolutions improve, transmission electron microscopes (TEMs) and scanning transmission electron microscopes (STEMs) become more sensitive to ambient conditions. State-of-the-art electron microscopes require state-of-the-art environments, and this means careful design and implementation of microscope sites, from the microscope room to the building that surrounds it. Laboratories have been constructed to house high-sensitive instruments with resolutions ranging down to sub-Angstrom levels; we present the various design philosophies used for some of these laboratories and our experiences with them. Four facilities are described: the National Center for Electron Microscopy OAM Laboratory at LBNL; the FEGTEM Facility at the University of Sheffield; the Center for Integrative Molecular Biosciences at TSRI; and the Advanced Microscopy Laboratory at ORNL.

  8. Surveillance for an outbreak of Encephalitozoon cuniculi infection in rabbits housed at a zoo and biosecurity countermeasures.

    Science.gov (United States)

    Fukui, Daisuke; Bando, Gen; Furuya, Koji; Yamaguchi, Masanori; Nakaoka, Yuji; Kosuge, Masao; Murata, Koichi

    2013-01-31

    An outbreak of encephalitozoonosis occurred in a rabbit colony at a zoo in Japan. Throughout the two years after the onset, all 42 rabbits were investigated clinically, pathologically and serologically for prevention and control of the disease. Eleven rabbits (11/42, 26.2%) showed clinical symptoms. Of 38 rabbits examined to detect specific antibodies against Encephalitozoon cuniculi, 71.1% (n=27) were found seropositive; 20 out of 30 clinically healthy rabbits (except for 8 clinical cases) were seropositive. The infection rate was 76.2% (32/42), including 5 pathologically diagnosed cases. The results of serological survey revealed that asymptomatic infection was widespread, even among clinically healthy rabbits. However, encephalitozoonosis was not found by pathological examination in any other species of animals kept in the same area within the zoo. Isolation and elimination of the rabbits with suspected infection based on the results of serological examination were carried out immediately; however, encephalitozoonosis continued to occur sporadically. Therefore, all the remaining rabbits were finally slaughtered. Then, the facility was closed, and all the equipment was disinfected. After a two-month interval, founder rabbits were introduced from encephalitozoonosis-free rabbitries for new colony formation. Since then, encephalitozoonosis has not been seen in any animals at the zoo. In this study, biosecurity countermeasures including staff education, epidemiological surveillance and application of an "all-out and all-in" system for rabbit colony establishment based on serological examination were successfully accomplished with regard to animal hygiene and public health for the eradication of E. cuniculi.

  9. 我国生物安全能力可持续发展的重点%Priorities of biosecurity capacity-building for sustainable development in China

    Institute of Scientific and Technical Information of China (English)

    郑涛; 沈倍奋; 黄培堂

    2012-01-01

    生物安全是指全球化时代国家有效应对生物及其技术因素的影响和威胁,维护和保障自身安全与利益的状态和能力.生物安全的能力建设主要包括监测、预警、鉴别、处置、恢复等方面.未来相当长时期我国生物安全能力建设应突出重点,有计划地加强针对高风险病原体的疫苗和药物基础与开发研究能力,全面加强基于建模与多种信息资源融合的风险预测与危害评估分析能力,重视加强新兴生物技术谬用的风险评估能力,确保生物安全能力的可持续发展.%Biosecurity refers to the effective response of countries to biological and biotechnical threats, safeguard and protect national security and interest in the era of globalization. Biosecurity capability building involves monitoring, early warning, identification, disposal and recovery. China should work out a long-term plan to strengthen the research and development of vaccines and drugs for high-risk pathogens, strengthen risk prediction and hazard assessment based on modeling and integration of a variety of information resources, and enhance the risk assessability of emerging biotechnology abuse to ensure the sustainable development of biosecurity capability.

  10. Laboratory-directed research and development: FY 1996 progress report

    International Nuclear Information System (INIS)

    This report summarizes the FY 1996 goals and accomplishments of Laboratory-Directed Research and Development (LDRD) projects. It gives an overview of the LDRD program, summarizes work done on individual research projects, and provides an index to the projects' principal investigators. Projects are grouped by their LDRD component: Individual Projects, Competency Development, and Program Development. Within each component, they are further divided into nine technical disciplines: (1) materials science, (2) engineering and base technologies, (3) plasmas, fluids, and particle beams, (4) chemistry, (5) mathematics and computational sciences, (6) atomic and molecular physics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) biosciences

  11. Laboratory-directed research and development: FY 1996 progress report

    Energy Technology Data Exchange (ETDEWEB)

    Vigil, J.; Prono, J. [comps.

    1997-05-01

    This report summarizes the FY 1996 goals and accomplishments of Laboratory-Directed Research and Development (LDRD) projects. It gives an overview of the LDRD program, summarizes work done on individual research projects, and provides an index to the projects` principal investigators. Projects are grouped by their LDRD component: Individual Projects, Competency Development, and Program Development. Within each component, they are further divided into nine technical disciplines: (1) materials science, (2) engineering and base technologies, (3) plasmas, fluids, and particle beams, (4) chemistry, (5) mathematics and computational sciences, (6) atomic and molecular physics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) biosciences.

  12. 实验动物与生物安全%Experimental Animals and Biosecurity

    Institute of Scientific and Technical Information of China (English)

    钱军; 孙玉成

    2011-01-01

    实验动物是从事科学研究、教学、生产、检定等的重要工具和支撑条件.随着科学技术的飞速发展,科学研究中使用的实验动物和实验用动物的种类、品系越来越多,生物安全问题已经明显地威胁到生物多样性、生态环境和人类健康.本文分析了实验动物的潜在生物安全危害,探讨了实验动物生物安全管理方面存在的问题并就应对实验动物生物安全提出了一些建议.%Experimental animals are an important tool and supporting condition for research , leaching, production, standardization. The species and strain of experimental animals used in research have been increased markedly alone with development al full speed of science and technique. But the biological diversity, ecological environment and human health have been threatened by experimental animals bio-safety issues in our country. This review analyzed the potential bio-safety hidden danger in experimental animals raising and use, investigated problems existed in experimentalanimals bio-safety control,and proposed some measures and advice to laboratory animals bio-safety.

  13. National Laboratory Planning: Developing Sustainable Biocontainment Laboratories in Limited Resource Areas.

    Science.gov (United States)

    Yeh, Kenneth B; Adams, Martin; Stamper, Paul D; Dasgupta, Debanjana; Hewson, Roger; Buck, Charles D; Richards, Allen L; Hay, John

    2016-01-01

    Strategic laboratory planning in limited resource areas is essential for addressing global health security issues. Establishing a national reference laboratory, especially one with BSL-3 or -4 biocontainment facilities, requires a heavy investment of resources, a multisectoral approach, and commitments from multiple stakeholders. We make the case for donor organizations and recipient partners to develop a comprehensive laboratory operations roadmap that addresses factors such as mission and roles, engaging national and political support, securing financial support, defining stakeholder involvement, fostering partnerships, and building trust. Successful development occurred with projects in African countries and in Azerbaijan, where strong leadership and a clear management framework have been key to success. A clearly identified and agreed management framework facilitate identifying the responsibility for developing laboratory capabilities and support services, including biosafety and biosecurity, quality assurance, equipment maintenance, supply chain establishment, staff certification and training, retention of human resources, and sustainable operating revenue. These capabilities and support services pose rate-limiting yet necessary challenges. Laboratory capabilities depend on mission and role, as determined by all stakeholders, and demonstrate the need for relevant metrics to monitor the success of the laboratory, including support for internal and external audits. Our analysis concludes that alternative frameworks for success exist for developing and implementing capabilities at regional and national levels in limited resource areas. Thus, achieving a balance for standardizing practices between local procedures and accepted international standards is a prerequisite for integrating new facilities into a country's existing public health infrastructure and into the overall international scientific community.

  14. National Laboratory Planning: Developing Sustainable Biocontainment Laboratories in Limited Resource Areas.

    Science.gov (United States)

    Yeh, Kenneth B; Adams, Martin; Stamper, Paul D; Dasgupta, Debanjana; Hewson, Roger; Buck, Charles D; Richards, Allen L; Hay, John

    2016-01-01

    Strategic laboratory planning in limited resource areas is essential for addressing global health security issues. Establishing a national reference laboratory, especially one with BSL-3 or -4 biocontainment facilities, requires a heavy investment of resources, a multisectoral approach, and commitments from multiple stakeholders. We make the case for donor organizations and recipient partners to develop a comprehensive laboratory operations roadmap that addresses factors such as mission and roles, engaging national and political support, securing financial support, defining stakeholder involvement, fostering partnerships, and building trust. Successful development occurred with projects in African countries and in Azerbaijan, where strong leadership and a clear management framework have been key to success. A clearly identified and agreed management framework facilitate identifying the responsibility for developing laboratory capabilities and support services, including biosafety and biosecurity, quality assurance, equipment maintenance, supply chain establishment, staff certification and training, retention of human resources, and sustainable operating revenue. These capabilities and support services pose rate-limiting yet necessary challenges. Laboratory capabilities depend on mission and role, as determined by all stakeholders, and demonstrate the need for relevant metrics to monitor the success of the laboratory, including support for internal and external audits. Our analysis concludes that alternative frameworks for success exist for developing and implementing capabilities at regional and national levels in limited resource areas. Thus, achieving a balance for standardizing practices between local procedures and accepted international standards is a prerequisite for integrating new facilities into a country's existing public health infrastructure and into the overall international scientific community. PMID:27559843

  15. Tutorials in mathematical biosciences

    CERN Document Server

    2008-01-01

    The book offers an easy introduction to fast growing research areas in evolution of species, population genetics, ecological models, and population dynamics. The first two chapters review the concept and methodologies of phylogenetic trees; computational schemes and illustrations are given, including applications such as tracing the origin of SARS and influenza. The third chapter introduces the reader to ecological models, including predator-prey models. This chapter includes and introduction to reaction-diffusion equations, which are used to analyze the ecological models. The next chapter reviews a broad range of ongoing research in population dynamics, including evolution of dispersal models; it also features interesting mathematical theorems and lists open problems. The final chapter deals with gene frequencies under the action of migration and selection. The book is addressed to readers at the level of grad students and researchers. A background in PDEs is provided.

  16. 55th Annual Canadian Society for Molecular Biosciences Conference on Epigenetics and Genomic Stability. Whistler, British Columbia, Canada, 14–18 March 2012.

    Science.gov (United States)

    Nelson, Christopher J; Ausió, Juan

    2012-06-01

    The 55th Annual Canadian Society for Molecular Biosciences Conference on Epigenetics and Genomic Stability in Whistler, Canada, 14-18 March 2012, brought together 31 speakers from different nationalities. The organizing committee, led by Jim Davie (Chair) at the University of Manitoba (Manitoba, Canada), consisted of several established researchers in the fields of chromatin and epigenetics from across Canada. The meeting was centered on the contribution of epigenetics to gene expression, DNA damage and repair, and the role of environmental factors. A few interesting talks on replication added some insightful information on the controversial issue of histone post-translational modifications as genuine epigenetic marks that are inherited through cell division.

  17. Laboratory capacity for diagnosis of foot-and-mouth disease in Eastern Africa: implications for the progressive control pathway

    DEFF Research Database (Denmark)

    Namatovu, Alice; Wekesa, Sabenzia Nabalayo; Tjørnehøj, Kirsten;

    2013-01-01

    at biosecurity level 3 and only three (Ethiopia, Kenya and Sudan) had identified FMD virus serotypes for all reported outbreaks. Based on their own country/region assessment, 12/13 of these countries/regions were below stage 3 of the PCP-FMD. Quarantine (77%) and vaccination (54%) were the major FMD control......%) participated in proficiency testing for FMD. Four (31%) laboratories had no quality management systems (QMS) in place and where QMS existed it was still deficient, thus, none of the laboratories had achieved accreditation for FMD diagnosis. Conclusions: This study indicates that FMD diagnostic capacity...

  18. HYDROMECHANICS LABORATORY

    Data.gov (United States)

    Federal Laboratory Consortium — Naval Academy Hydromechanics Laboratory The Naval Academy Hydromechanics Laboratory (NAHL) began operations in Rickover Hall in September 1976. The primary purpose...

  19. Biomedical laboratories: architecture and radioprotection principles

    International Nuclear Information System (INIS)

    In institutions where biological research are made and some technologies make use of radioisotope, the radiation protection is an issue of biosecurity for conceptual reasons. In the process of architectural design of Biomedical Laboratories, engineering and architecture reveal interfaces with other areas of knowledge and specific concepts. Exploring the role of architectural design in favor of personal and environmental protection in biological containment laboratories that handle non-sealed sources in research, the work discusses the triad that compose the principle of containment in health environments: best practices, protective equipment, physical facilities, with greater emphasis on the latter component. The shortcomings of the design process are reflected in construction and in use-operation and maintenance of these buildings, with direct consequences on the occupational health and safety, environmental and credibility of work processes. In this context, the importance of adoption of alternatives to improve the design process is confirmed, taking into account the early consideration of several variables involved and providing subsidies to the related laboratories . The research, conducted at FIOCRUZ - a Brazilian health institution, developed from the analysis of the participants in the architectural project, aiming at the formulation of design guidelines which could contribute to the rationalisation of this kind of building construction

  20. Laboratory directed research and development: FY 1997 progress report

    Energy Technology Data Exchange (ETDEWEB)

    Vigil, J.; Prono, J. [comps.

    1998-05-01

    This is the FY 1997 Progress Report for the Laboratory Directed Research and Development (LDRD) program at Los Alamos National Laboratory. It gives an overview of the LDRD program, summarizes work done on individual research projects, relates the projects to major Laboratory program sponsors, and provides an index to the principal investigators. Project summaries are grouped by their LDRD component: Competency Development, Program Development, and Individual Projects. Within each component, they are further grouped into nine technical categories: (1) materials science, (2) chemistry, (3) mathematics and computational science, (4) atomic and molecular physics and plasmas, fluids, and particle beams, (5) engineering science, (6) instrumentation and diagnostics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) bioscience.

  1. Laboratory Directed Research and Development FY 1998 Progress Report

    Energy Technology Data Exchange (ETDEWEB)

    John Vigil; Kyle Wheeler

    1999-04-01

    This is the FY 1998 Progress Report for the Laboratory Directed Research and Development (LDRD) Program at Los Alamos National Laboratory. It gives an overview of the LDRD Program, summarizes work done on individual research projects, relates the projects to major Laboratory program sponsors, and provides an index to the principle investigators. Project summaries are grouped by their LDRD component: Competency Development, Program Development, and Individual Projects. Within each component, they are further grouped into nine technical categories: (1) materials science, (2) chemistry, (3) mathematics and computational science, (4) atomic, molecular, optical, and plasma physics, fluids, and particle beams, (5) engineering science, (6) instrumentation and diagnostics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) bioscience.

  2. Field application of a combined pig and poultry market chain and risk pathway analysis within the Pacific Islands region as a tool for targeted disease surveillance and biosecurity.

    Science.gov (United States)

    Brioudes, Aurélie; Gummow, Bruce

    2016-07-01

    Limited resources are one of the major constraints in effective disease monitoring and control in developing countries. This paper examines the pig and poultry market chains of four targeted Pacific Island countries and territories (PICTs): Fiji, Papua New Guinea, Solomon Islands and Vanuatu and combines them with a risk pathway analysis to identify the highest risk areas (risk hotspots) and risky practices and behaviours (risk factors) of animal disease introduction and/or spread, using highly pathogenic avian influenza (HPAI) and foot-and-mouth disease (FMD) as model diseases because of their importance in the region. The results show that combining a market chain analysis with risk pathways is a practical way of communicating risk to animal health officials and improving biosecurity. It provides a participatory approach that helps officials to better understand the trading regulations in place in their country and to better evaluate their role as part of the control system. Common risk patterns were found to play a role in all four PICTs. Legal trade pathways rely essentially on preventive measures put in place in the exporting countries while no or only limited control measures are undertaken by the importing countries. Legal importations of animals and animal products are done mainly by commercial farms which then supply local smallholders. Targeting surveillance on these potential hotspots would limit the risk of introduction and spread of animal diseases within the pig and poultry industry and better rationalize use of skilled manpower. Swill feeding is identified as a common practice in the region that represents a recognized risk factor for dissemination of pathogens to susceptible species. Illegal introduction of animals and animal products is suspected, but appears restricted to small holder farms in remote areas, limiting the risk of spread of transboundary animal diseases along the market chain. Introduction of undeclared goods hidden within a legal

  3. Field application of a combined pig and poultry market chain and risk pathway analysis within the Pacific Islands region as a tool for targeted disease surveillance and biosecurity.

    Science.gov (United States)

    Brioudes, Aurélie; Gummow, Bruce

    2016-07-01

    Limited resources are one of the major constraints in effective disease monitoring and control in developing countries. This paper examines the pig and poultry market chains of four targeted Pacific Island countries and territories (PICTs): Fiji, Papua New Guinea, Solomon Islands and Vanuatu and combines them with a risk pathway analysis to identify the highest risk areas (risk hotspots) and risky practices and behaviours (risk factors) of animal disease introduction and/or spread, using highly pathogenic avian influenza (HPAI) and foot-and-mouth disease (FMD) as model diseases because of their importance in the region. The results show that combining a market chain analysis with risk pathways is a practical way of communicating risk to animal health officials and improving biosecurity. It provides a participatory approach that helps officials to better understand the trading regulations in place in their country and to better evaluate their role as part of the control system. Common risk patterns were found to play a role in all four PICTs. Legal trade pathways rely essentially on preventive measures put in place in the exporting countries while no or only limited control measures are undertaken by the importing countries. Legal importations of animals and animal products are done mainly by commercial farms which then supply local smallholders. Targeting surveillance on these potential hotspots would limit the risk of introduction and spread of animal diseases within the pig and poultry industry and better rationalize use of skilled manpower. Swill feeding is identified as a common practice in the region that represents a recognized risk factor for dissemination of pathogens to susceptible species. Illegal introduction of animals and animal products is suspected, but appears restricted to small holder farms in remote areas, limiting the risk of spread of transboundary animal diseases along the market chain. Introduction of undeclared goods hidden within a legal

  4. Implementation of ML Using Naïve Bayes Algorithm for Identifying Disease-Treatment Relation in Bio-Science Text

    Directory of Open Access Journals (Sweden)

    T.F. Michael Raj

    2013-01-01

    Full Text Available In recent years many successful machine learning applications have been developed, ranging from datamining programs to information-filtering systems that learn users' reading preferences. At the same time, there have been important advances in the theory and algorithms that can be used identify the diseases and treatment relations in a Bio-Science text. Imagine a computer learns from medical records which treatments are most effective for new diseases. Having the machine learning concept behind we have proposed a Machine Learning (ML approach based on Naïve Bayes (NB algorithm to improve the automatic disease identification in the medical field. And also we have improved text classification by using an integrated model.

  5. Biosecurity subject construction and capacity building of China%我国生物安全学科建设与能力发展

    Institute of Scientific and Technical Information of China (English)

    郑涛

    2011-01-01

    Biosecurity is defined as respond effectively to biological damage associated with various destructive factors and threats, maintain and protect national interests, security and public health in era of globalization. In the subject construction , biosecuritics is to study development mechanisms of various biological risk factors, biological hazard assessment, capacity building of prevention and response, promoting peaceful development and application of life sciences and biotechnology , maintenance and protection of national interests, security and public health. This paper put forward that the core content of biosecurity is capacity building, especially the ability of biological risk monitor and response.%总体上生物安全是指全球化时代国家有效应对与生物相关的内外各种损害性、破坏性因素的影响和威胁,维护和保障国家利益、安全和国民健康的状态和能力.在学科上,生物安全学是研究各种生物风险因素发生发展机制与危害评估、防御能力建设与应对措施,促进生命科学与生物技术和平发展与应用,维护和保障国家利益和国民健康的科学.生物安全的核心内容是生物安全能力,特别是对生物风险的认识和应对生物风险的能力.

  6. Laboratory Directed Research and Development Program FY 2006

    Energy Technology Data Exchange (ETDEWEB)

    Hansen (Ed.), Todd

    2007-03-08

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness.

  7. Laboratory Directed Research and Development FY 2000 Annual Progress Report

    Energy Technology Data Exchange (ETDEWEB)

    Los Alamos National Laboratory

    2001-05-01

    This is the FY00 Annual Progress report for the Laboratory Directed Research and Development (LDRD) Program at Los Alamos National Laboratory. It gives an overview of the LDRD Program, summarizes progress on each project conducted during FY00, characterizes the projects according to their relevance to major funding sources, and provides an index to principal investigators. Project summaries are grouped by LDRD component: Directed Research and Exploratory Research. Within each component, they are further grouped into the ten technical categories: (1) atomic, molecular, optical, and plasma physics, fluids, and beams, (2) bioscience, (3) chemistry, (4) computer science and software engineering, (5) engineering science, (6) geoscience, space science, and astrophysics, (7) instrumentation and diagnostics, (8) materials science, (9) mathematics, simulation, and modeling, and (10) nuclear and particle physics.

  8. Laboratory Directed Research and Development FY 2000

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Todd; Levy, Karin

    2001-02-27

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Annual report on Laboratory Directed Research and Development for FY2000.

  9. Laboratory Directed Research and Development FY 2000

    International Nuclear Information System (INIS)

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Annual report on Laboratory Directed Research and Development for FY2000

  10. Bioseguridad con énfasis en contaminantes biológicos en trabajadores de la salud Bio-security with emphasis in biological polluting agents in health workers

    Directory of Open Access Journals (Sweden)

    Ana Maria Ardila

    2009-12-01

    Full Text Available Los trabajadores de la salud del servicio de urgencias están expuestos frecuentemente a diferentes peligros, entre ellos a la exposición de los contaminantes biológicos. Estudio de carácter descriptivo, con el objetivo de caracterizar socio-demográficamente a los trabajadores, además de verificar el nivel de aplicación de las normas de bioseguridad, en el servicio de urgencias de una institución de salud en la ciudad de Bogota-Colombia 68.3 % de los trabajadores se encuentra vinculados mediante contrato en la modalidad de prestación de servicios, el 31.7%, esta vinculado en la modalidad de término indefinido. El 44.6% del personal no ha recibido capacitación sobre el tema de bioseguridad, un 42.4 % no aplican la técnica adecuada de lavado de manos. En relación con el aspecto de re-encapuchar las agujas, se encontró que el 31% realizan esta práctica. El 100% de los trabajadores tienen el esquema completo de la vacuna Hepatitis B, pero el mismo porcentaje no tiene medición de anticuerpos de hepatitis B. Es fundamental el suministro de elementos de protección personal y dotación de elementos y recipientes que contribuyan a la bioseguridad. Se deben realizar actividades pedagógicas para sensibilizar y crear conciencia crítica a la organización y todo el personal que labora en el área de urgencias, sobre los peligros y consecuencias a que se exponen en su lugar de trabajo.Health workers of the emergency service are frequently exposed to different dangers, among them the contact with biological polluting agents. This is a study of descriptive character, with the objective to characterize workers on social demographic aspects, and also to verify the level of application of the bio-security norms at the emergency services of a health institution in the city of Bogota, Colombia. 68,3% of the workers are with a contract in the modality of benefit of services, the 31,7%, are in the modality of indefinite term. 44,6% of the personnel

  11. Analytical Laboratories

    Data.gov (United States)

    Federal Laboratory Consortium — NETL’s analytical laboratories in Pittsburgh, PA, and Albany, OR, give researchers access to the equipment they need to thoroughly study the properties of materials...

  12. Computational Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory contains a number of commercial off-the-shelf and in-house software packages allowing for both statistical analysis as well as mathematical modeling...

  13. National laboratories

    International Nuclear Information System (INIS)

    The foundation of a 'National Laboratory' which would support a Research center in synchrotron radiation applications is proposed. The essential features of such a laboratory differing of others centers in Brazil are presented. (L.C.)

  14. Laboratory Tests

    Science.gov (United States)

    Laboratory tests check a sample of your blood, urine, or body tissues. A technician or your doctor ... compare your results to results from previous tests. Laboratory tests are often part of a routine checkup ...

  15. Pig producers' perceptions of the Influenza Pandemic H1N1/09 outbreak and its effect on their biosecurity practices in Australia.

    Science.gov (United States)

    Hernández-Jover, Marta; Taylor, Melanie; Holyoake, Patricia; Dhand, Navneet

    2012-10-01

    The Influenza Pandemic (H1N1/09) virus was first reported in humans in Mexico in April 2009 and a pandemic level was declared on 11th of June 2009 by the World Health Organization (Chan, 2009; WHO, 2009a). Public misconceptions about the transmission of H1N1/09 were caused by the inadequate naming of the disease as 'swine influenza'. This cross-sectional study was conducted at the height of the outbreak in the Australian human population and before the virus was reported in the first piggery in Australia in July 2009 (OIE, 2009b; Holyoake et al., 2011). The aims of this study were to evaluate pig producers' perceptions about the virus and the outbreak financial impact and influence on on-farm biosecurity practices. A questionnaire was designed and posted to Australian Pork Limited (APL) members (n=460), obtaining responses from 182 producers (39.6%). Pig producers had good general knowledge on potential transmission pathways for H1N1/09 between people, with direct or close contact with a sick person perceived as the most likely pathways. Changes on biosecurity practices, such as asking visitors if they had recently been overseas (27.8%) and not allowing any visitor to inspect their pigs (18.3%), were reported among respondents. In addition, approximately 40% of producers asked their employees to notify flu like symptoms, consulted a veterinarian on H1N1/09 and visited websites to seek information on H1N1/09. A higher adoption of these practices was observed among large (>100 sows) than small herds. Only 2.9% of respondents reported a reduction in pig sales during the outbreak. However, approximately one third of producers reported being financially and emotionally stressed, 38.2% were distressed about the health of their pigs and 16.7% about their own health. The most important sources of information were APL (93%), veterinarians (89%) and the state Department of Primary Industries (DPI) (75%). The first two considered the most trusted sources of information

  16. The integration of the "spirituality in medicine" curriculum into the osteopathic communication curriculum at Kansas City University of Medicine and Biosciences.

    Science.gov (United States)

    Talley, Jan A; Magie, Richard

    2014-01-01

    With grant funding from the John Templeton Spirituality and Medicine Curricular Award to the George Washington Institute for Spirituality and Health, faculty at Kansas City University of Medicine and Biosciences (KCUMB) developed the "Spirituality in Medicine" curriculum. In developing the curriculum, faculty took into consideration competencies required by the Association of American Medical Colleges and qualitative results from surveys of medical school applicants and enrolled students. Strategies for curriculum delivery included lectures, panel discussions, role-playing, and training in the use of a spirituality assessment tool. A majority of the 250 students who received the training in 2010-2011 were able to demonstrate the following competencies: (1) being sensitive to patients' spiritual and cultural needs, (2) assessing patients' and their own spiritual needs, (3) appropriately using chaplain services for patient care, and (4) understanding the effects of health disparities and ethical issues on patient care. Challenges to implementation included a reduction in chaplain availability due to the economic downturn, a lack of student exposure to direct patient care during shadowing, too little religious diversity among chaplains, and changes in assignment schedules. New competencies required by the National Board of Osteopathic Medical Examiners overlap with and help ensure sustainability of the Spirituality in Medicine curriculum. KCUMB leaders have incorporated the use of the spirituality assessment tool into other parts of the curriculum and into service experiences, and they have introduced a new elective in palliative care. Synergistic efforts by faculty leaders for this initiative were critical to the implementation of this curriculum. PMID:24280841

  17. Laboratory Building.

    Energy Technology Data Exchange (ETDEWEB)

    Herrera, Joshua M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-03-01

    This report is an analysis of the means of egress and life safety requirements for the laboratory building. The building is located at Sandia National Laboratories (SNL) in Albuquerque, NM. The report includes a prescriptive-based analysis as well as a performance-based analysis. Following the analysis are appendices which contain maps of the laboratory building used throughout the analysis. The top of all the maps is assumed to be north.

  18. Dynamics Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Dynamics Lab replicates vibration environments for every Navy platform. Testing performed includes: Flight Clearance, Component Improvement, Qualification, Life...

  19. Chemistry Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Purpose: To conduct fundamental studies of highway materials aimed at understanding both failure mechanisms and superior performance. New standard test methods are...

  20. Montlake Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The NWFSC conducts critical fisheries science research at its headquarters in Seattle, WA and at five research stations throughout Washington and Oregon. The unique...

  1. Visualization Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Evaluates and improves the operational effectiveness of existing and emerging electronic warfare systems. By analyzing and visualizing simulation results...

  2. Learning Laboratory.

    Science.gov (United States)

    Hay, Lyn; Callison, Daniel

    2000-01-01

    Considers the school library media center as an information learning laboratory. Topics include information literacy; Kuhlthau's Information Search Process model; inquiry theory and approach; discovery learning; process skills of laboratory science; the information scientist; attitudes of media specialists, teachers, and students; displays and Web…

  3. Development of a methylation marker set for forensic age estimation using analysis of public methylation data and the Agena Bioscience EpiTYPER system.

    Science.gov (United States)

    Freire-Aradas, A; Phillips, C; Mosquera-Miguel, A; Girón-Santamaría, L; Gómez-Tato, A; Casares de Cal, M; Álvarez-Dios, J; Ansede-Bermejo, J; Torres-Español, M; Schneider, P M; Pośpiech, E; Branicki, W; Carracedo, Á; Lareu, M V

    2016-09-01

    Individual age estimation has the potential to provide key information that could enhance and extend DNA intelligence tools. Following predictive tests for externally visible characteristics developed in recent years, prediction of age could guide police investigations and improve the assessment of age-related phenotype expression patterns such as hair colour changes and early onset of male pattern baldness. DNA methylation at CpG positions has emerged as the most promising DNA tests to ascertain the individual age of the donor of a biological contact trace. Although different methodologies are available to detect DNA methylation, EpiTYPER technology (Agena Bioscience, formerly Sequenom) provides useful characteristics that can be applied as a discovery tool in localized regions of the genome. In our study, a total of twenty-two candidate genomic regions, selected from the assessment of publically available data from the Illumina HumanMethylation 450 BeadChip, had a total of 177 CpG sites with informative methylation patterns that were subsequently investigated in detail. From the methylation analyses made, a novel age prediction model based on a multivariate quantile regression analysis was built using the seven highest age-correlated loci of ELOVL2, ASPA, PDE4C, FHL2, CCDC102B, C1orf132 and chr16:85395429. The detected methylation levels in these loci provide a median absolute age prediction error of ±3.07years and a percentage of prediction error relative to the age of 6.3%. We report the predictive performance of the developed model using cross validation of a carefully age-graded training set of 725 European individuals and a test set of 52 monozygotic twin pairs. The multivariate quantile regression age predictor, using the CpG sites selected in this study, has been placed in the open-access Snipper forensic classification website. PMID:27337627

  4. Lawrence Livermore National Laboratory Environmental Report 2013

    Energy Technology Data Exchange (ETDEWEB)

    Jones, H. E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Bertoldo, N. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Blake, R. G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Cerruti, S. J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Dibley, V. R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Doman, J. L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Fish, C. B. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Grayson, A. R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Heidecker, K. R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Kumamoto, G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); MacQueen, D. H. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Montemayor, W. E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Ottaway, H. L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Paterson, L. E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Revelli, M. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Rosene, C. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Terrill, A. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wegrecki, A. M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wilson, K. R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Woollett, J. S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Veseliza, R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2014-10-01

    Lawrence Livermore National Laboratory (LLNL) is a premier research laboratory that is part of the National Nuclear Security Administration (NNSA) within the U.S. Department of Energy (DOE). As a national security laboratory, LLNL is responsible for ensuring that the nation’s nuclear weapons remain safe, secure, and reliable. The Laboratory also meets other pressing national security needs, including countering the proliferation of weapons of mass destruction and strengthening homeland security, and conducting major research in atmospheric, earth, and energy sciences; bioscience and biotechnology; and engineering, basic science, and advanced technology. The Laboratory is managed and operated by Lawrence Livermore National Security, LLC (LLNS), and serves as a scientific resource to the U.S. government and a partner to industry and academia. LLNL operations have the potential to release a variety of constituents into the environment via atmospheric, surface water, and groundwater pathways. Some of the constituents, such as particles from diesel engines, are common at many types of facilities while others, such as radionuclides, are unique to research facilities like LLNL. All releases are highly regulated and carefully monitored. LLNL strives to maintain a safe, secure and efficient operational environment for its employees and neighboring communities. Experts in environment, safety and health (ES&H) support all Laboratory activities. LLNL’s radiological control program ensures that radiological exposures and releases are reduced to as low as reasonably achievable to protect the health and safety of its employees, contractors, the public, and the environment. LLNL is committed to enhancing its environmental stewardship and managing the impacts its operations may have on the environment through a formal Environmental Management System. The Laboratory encourages the public to participate in matters related to the Laboratory’s environmental impact on the

  5. Laboratory Tests

    Science.gov (United States)

    ... Medical Devices Radiation-Emitting Products Vaccines, Blood & Biologics Animal & ... or conditions. What are lab tests? Laboratory tests are medical procedures that involve testing samples of blood, urine, or other tissues or ...

  6. Problems facing biosecurity capability building in China%认清形势解决问题,加快我国生物安全能力建设步伐

    Institute of Scientific and Technical Information of China (English)

    郑涛; 黄培堂; 沈倍奋

    2014-01-01

    生物安全是国家安全的重要组成部分,是民族复兴、实现中国梦的重要保证。目前我国面临着日益严峻的生物威胁形势,生物安全能力建设存在一些亟待解决的问题,主要体现在对不同生物威胁形式的相互关系认识不清;对军民融合发展的责权利认识不清;对长期可持续发展与近期应急能力建设的平衡关系认识不清;对生物安全能力建设的多学科交叉趋势认识不清;对破解美国等西方发达国家对我国技术封锁和市场垄断的迫切性认识不清。%Biosecurity is an important component of national security and an important guarantee for national revival and the realization of China's dream.However China is facing increasingly serious biological threats .Biosecurity capability build-ing has some problem .For exanyple ,people have a vague idea about the relationship between different biological threats ,the duties and rights of civil-military integration development , the balance between sustainable development and emergency pre-vention and control capacity-building, multidisciplinary convergence of biosecurity capacity-building, and about ways to break down the technological blockade and market monopoly by the United States and other developed countries .

  7. Argonne's Laboratory computing center - 2007 annual report.

    Energy Technology Data Exchange (ETDEWEB)

    Bair, R.; Pieper, G. W.

    2008-05-28

    Argonne National Laboratory founded the Laboratory Computing Resource Center (LCRC) in the spring of 2002 to help meet pressing program needs for computational modeling, simulation, and analysis. The guiding mission is to provide critical computing resources that accelerate the development of high-performance computing expertise, applications, and computations to meet the Laboratory's challenging science and engineering missions. In September 2002 the LCRC deployed a 350-node computing cluster from Linux NetworX to address Laboratory needs for mid-range supercomputing. This cluster, named 'Jazz', achieved over a teraflop of computing power (1012 floating-point calculations per second) on standard tests, making it the Laboratory's first terascale computing system and one of the 50 fastest computers in the world at the time. Jazz was made available to early users in November 2002 while the system was undergoing development and configuration. In April 2003, Jazz was officially made available for production operation. Since then, the Jazz user community has grown steadily. By the end of fiscal year 2007, there were over 60 active projects representing a wide cross-section of Laboratory expertise, including work in biosciences, chemistry, climate, computer science, engineering applications, environmental science, geoscience, information science, materials science, mathematics, nanoscience, nuclear engineering, and physics. Most important, many projects have achieved results that would have been unobtainable without such a computing resource. The LCRC continues to foster growth in the computational science and engineering capability and quality at the Laboratory. Specific goals include expansion of the use of Jazz to new disciplines and Laboratory initiatives, teaming with Laboratory infrastructure providers to offer more scientific data management capabilities, expanding Argonne staff use of national computing facilities, and improving the scientific

  8. Laboratory Directed Research and Development FY2010 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Jackson, K J

    2011-03-22

    A premier applied-science laboratory, Lawrence Livermore National Laboratory (LLNL) has at its core a primary national security mission - to ensure the safety, security, and reliability of the nation's nuclear weapons stockpile without nuclear testing, and to prevent and counter the spread and use of weapons of mass destruction: nuclear, chemical, and biological. The Laboratory uses the scientific and engineering expertise and facilities developed for its primary mission to pursue advanced technologies to meet other important national security needs - homeland defense, military operations, and missile defense, for example - that evolve in response to emerging threats. For broader national needs, LLNL executes programs in energy security, climate change and long-term energy needs, environmental assessment and management, bioscience and technology to improve human health, and for breakthroughs in fundamental science and technology. With this multidisciplinary expertise, the Laboratory serves as a science and technology resource to the U.S. government and as a partner with industry and academia. This annual report discusses the following topics: (1) Advanced Sensors and Instrumentation; (2) Biological Sciences; (3) Chemistry; (4) Earth and Space Sciences; (5) Energy Supply and Use; (6) Engineering and Manufacturing Processes; (7) Materials Science and Technology; Mathematics and Computing Science; (8) Nuclear Science and Engineering; and (9) Physics.

  9. Education: Bioscience Education through Bioparks.

    Science.gov (United States)

    Robinson, Michael H.

    1988-01-01

    Suggests creating a biological park to stress the interrelationships between plants and animals. States that the techniques of a zoo should be applied to paleontology, anatomy, anthropology. Gives advantages of this creative concept. (RT)

  10. The interfacial bioscience grand challenge.

    Energy Technology Data Exchange (ETDEWEB)

    Lane, Pamela; Stevens, Mark Jackson; Jacobsen, Richard B.; Hong, Joohee; Ayson, Marites J.; Crozier, Paul Stewart; Wood, Nichole L.; Schoeniger, Joseph S.; Kruppa, Gary Hermann; Sale, Kenneth L.; Young, Malin M.; Faulon, Jean-Loup Michel; Burns, Alan Richard; Evans, Kervin O.; Novak, Petr

    2004-03-01

    This report is broken down into the following 3 sections: (1) Chemical Cross-linking and Mass Spectrometry Applied to Determination of Protein Structure and Dynamics; (2) Computational Modeling of Membrane Protein Structure and Dynamics; and (3) Studies of Toxin-Membrane Interactions using Single Molecule Biophysical Methods.

  11. Challenges of the Unified Health System: present status of public laboratory services in 31 cities of Minas Gerais, Brazil

    Directory of Open Access Journals (Sweden)

    Pedro Guatimosim Vidigal

    2014-04-01

    Full Text Available Introduction: Modifications in the Brazilian Unified Health System (SUS have led to a significant improvement in the national health indexes. However, some challenges still need to be faced, especially concerning SUS patients' access to high-quality laboratory support services.Objective: To evaluate the present status of laboratory services in SUS in 31 cities of Minas Gerais, Brazil, between 2008 and 2011.Material and method: This analysis was performed through data from the Information Technology Department of SUS (DATASUS and through interviews with local public health managers with structured questionnaires.Results: Among all the studied cities, 21 had their own laboratory, 90.2% of which were in precarious conditions, not meeting the requirements established by the legislation in force, and employing inappropriate procedures and techniques, in addition to using obsolete equipment. The range of available laboratory tests was limited, what demanded the services of supporting laboratories. None of the evaluated laboratories developed any systematic activity on quality management, including control of analytical quality, maintenance of laboratory equipment, calibration and performance evaluation of critical equipment, continuing education programs, and safety and biosecurity.Conclusion: The effective role of laboratory test results in medical decision is unquestionably impaired, risking the safety of SUS patients. The present work reveals the deficiencies of public laboratory services in Minas Gerais, and proposes a new management model, which is able to associate operational quality, technological development and optimization of human and material resources with higher productivity.

  12. The Role of a National Biocontainment Laboratory in Emergencies.

    Science.gov (United States)

    Le Duc, James W; Ksiazek, Thomas G

    2015-01-01

    Over a decade ago, the National Institutes of Health awarded partial support for the construction and operation of 2 National Biocontainment Laboratories, with the condition that they would be available to assist in the event of public health emergencies-although how a biocontainment facility located on an academic campus might contribute was not defined. Here we offer examples of how one of these laboratories has contributed to a coordinated response to 2 recent international public health emergencies. Essential assets for success include highly trained and experienced staff, access to reference pathogens and reagents, cutting-edge knowledge of the field, appropriate biocontainment facilities, robust biosafety and biosecurity programs, and availability of modern instrumentation. The ability to marry the strengths of academia in basic and applied research with access to appropriate biocontainment facilities while drawing on a highly skilled cadre of experienced experts has proven extremely valuable in the response to recent national emergencies and will continue to do so in the future. Areas where additional planning and preparation are needed have also been identified through these experiences.

  13. The role biomedical science laboratories can play in improving science knowledge and promoting first-year nursing academic success

    Science.gov (United States)

    Arneson, Pam

    The Role Biomedical Science Laboratories Can Play In Improving Science Knowledge and Promoting First-Year Nursing Academic Success The need for additional nursing and health care professionals is expected to increase dramatically over the next 20 years. With this in mind, students must have strong biomedical science knowledge to be competent in their field. Some studies have shown that participation in bioscience laboratories can enhance science knowledge. If this is true, an analysis of the role bioscience labs have in first-year nursing academic success is apposite. In response, this study sought to determine whether concurrent enrollment in anatomy and microbiology lecture and lab courses improved final lecture course grades. The investigation was expanded to include a comparison of first-year nursing GPA and prerequisite bioscience concurrent lecture/lab enrollment. Additionally, research has indicated that learning is affected by student perception of the course, instructor, content, and environment. To gain an insight regarding students' perspectives of laboratory courses, almost 100 students completed a 20-statement perception survey to understand how lab participation affects learning. Data analyses involved comparing anatomy and microbiology final lecture course grades between students who concurrently enrolled in the lecture and lab courses and students who completed the lecture course alone. Independent t test analyses revealed that there was no significant difference between the groups for anatomy, t(285) = .11, p = .912, but for microbiology, the lab course provided a significant educational benefit, t(256) = 4.47, p = .000. However, when concurrent prerequisite bioscience lecture/lab enrollment was compared to non-concurrent enrollment for first-year nursing GPA using independent t test analyses, no significant difference was found for South Dakota State University, t(37) = -1.57, p = .125, or for the University of South Dakota, t(38) = -0.46, p

  14. 世博期间实验室生物安全风险评估及对策%Risk Assessment and Countermeasures of Laboratory Biosafety during EXPO 2010

    Institute of Scientific and Technical Information of China (English)

    范惠莹; 李颐; 蔡明毅; 朱红梅; 胡佳青

    2011-01-01

    目的 对世博期间上海市静安区疾控实验室生物安全进行风险评估并提出对策.方法 采用澳大利亚和新西兰的风险管理标准和专家评估法,对实验室生物安全进行风险评估.结果 火灾为极高风险生物安全事件;生物样本和茵毒种丢失,茵毒种感染,地震为高风险生物安全事件;水灾,实验室人员刺伤、切割伤或擦伤为中风险生物安全事件;实验室人员皮肤、粘膜污染,生物安全柜外环境重度污染等为低风险生物安全事件.结论 针对风险水平分级采取应对和处置措施,极高和高水平风险应优先考虑,积极应对;中等水平风险则采取常态应对措施;中等和低水平风险应加强监测,一旦发现风险水平升级,则应提高应对措施和策略水平.%Objective The risk assessment and countermeasures of laboratory biosafety during EXPO 2010 in Jingan District of Shanghai. Method By using the standard of risk management of Australia and New Zealand, and the expert evaluating method, risk assessment of laboratory biosafety was made during Expo 2010 in Jingan district. Result Fire is the highest risk biosecurity event; loss of biological sample and poisonous species of bacteria, infection of toxic species, and earthquake is high -risk biosecurity event; floods, laboratory personnel stabbed, cuts or abrasions is the middle bio - security risk event; laboratory personnel skin and mucous membrane contamination, biological safety cabinets and other outside the heavily polluted environment is low biosecurity risk event. Conclusion The prevention and controlling risk of biosecurity event should be improved step by step under rules including prevention as primary, prevention and emergency treatment as equal attention, improvement of urgent management.

  15. International perspectives on mitigating laboratory biorisks.

    Energy Technology Data Exchange (ETDEWEB)

    Pinard, William J.; Salazar, Carlos A.

    2010-11-01

    The International Perspectives on Mitigating Laboratory Biorisks workshop, held at the Renaissance Polat Istanbul Hotel in Istanbul, Republic of Turkey, from October 25 to 27, 2010, sought to promote discussion between experts and stakeholders from around the world on issues related to the management of biological risk in laboratories. The event was organized by Sandia National Laboratories International Biological Threat Reduction program, on behalf of the US Department of State Biosecurity Engagement Program and the US Department of Defense Cooperative Biological Engagement Program. The workshop came about as a response to US Under Secretary of State Ellen O. Tauscher's statements in Geneva on December 9, 2009, during the Annual Meeting of the States Parties to the Biological Weapons Convention (BWC). Pursuant to those remarks, the workshop was intended to provide a forum for interested countries to share information on biorisk management training, standards, and needs. Over the course of the meeting's three days, participants discussed diverse topics such as the role of risk assessment in laboratory biorisk management, strategies for mitigating risk, measurement of performance and upkeep, international standards, training and building workforce competence, and the important role of government and regulation. The meeting concluded with affirmations of the utility of international cooperation in this sphere and recognition of positive prospects for the future. The workshop was organized as a series of short presentations by international experts on the field of biorisk management, followed by breakout sessions in which participants were divided into four groups and urged to discuss a particular topic with the aid of a facilitator and a set of guiding questions. Rapporteurs were present during the plenary session as well as breakout sessions and in particular were tasked with taking notes during discussions and reporting back to the assembled participants

  16. Identification of Epiphyas postvittana for biosecurity using DNA barcoding%利用条形码技术鉴定苹浅褐卷蛾

    Institute of Scientific and Technical Information of China (English)

    和淑琪; 查涛; 蒋小龙; 桂富荣; 陈斌; 李正跃

    2011-01-01

    Light brown apple moth (LBAM), Epiphyas postvittana, is a leafroller pest native to Australia and currently has limited distribution around the world. As a serious pest in its current distribution areas, it is well known for its polymorphism with respect to its morphology. Morphological identification of E. postvittana has been problematic which increased the risk of it esacaping detection at the border of countries that wish to regulate this pest. In this study, we sequenced the COI gene from 26 samples of E. postvittana from five populations in New Zealand. We found that the intraspecies variation of E. postvittana is less than 3 %, while interspecies variation between E. postvittana and other tortricid species available in the barcode of life database (BOLD) system is much greater than 3%. This result confirms that using barcodes for identification of E. postvittana for biosecurity purposes is practical.%苹浅褐卷蛾原产澳大利亚,目前仅分布于少数地区,是澳大利亚、新西兰及英国等国家多种经济作物上的重要害虫,苹浅褐卷蛾形态具有多态性,对其形态鉴定一直非常困难,由此也增加了该虫在口岸上的入侵风险.本研究使用DNA条形码技术(barcoding)测定了采集自新西兰5个不同地区苹浅褐卷蛾种群26个样本的细胞色素酶I(COI)序列.研究表明,苹浅褐卷蛾种内COI序列差异远小于3%,而与BOLD数据库中卷蛾科其他种类的种间差异约为7%~16%,远大于3%.该结果肯定了条形码技术能够成为口岸快速、准确鉴定苹浅褐卷蛾的有效方法.

  17. Challenges and opportunities for early-career Teaching-Focussed academics in the biosciences [v2; ref status: indexed, http://f1000r.es/5c2

    Directory of Open Access Journals (Sweden)

    Katharine Hubbard

    2015-04-01

    Full Text Available Twenty-seven percent of academics in UK Higher Education (HE are in Teaching-Focussed positions, making major contributions to undergraduate programmes in an era of high student expectations when it comes to teaching quality. However, institutional support for Teaching-Focussed academics is often limited, both in terms of peer networking and opportunities for career development. As four early-career stage Teaching-Focussed academics working in a variety of institutions, we explore what motivated our choices to make teaching our primary academic activity, and the challenges that we have faced in doing so. In addition to highlighting the need for universities to fully recognise the achievements of teaching staff, we discuss the role that the various biosciences learned societies have in supporting Teaching-Focussed academics. We identify that there is a need for the learned societies to come together and pool their expertise in this area. The fragmented nature of the Teaching-Focussed academic community means that clear sources of national support are needed in order to best enable the next generation of bioscience educators to reach their full potential.

  18. Saxton Transportation Operations Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Saxton Transportation Operations Laboratory (Saxton Laboratory) is a state-of-the-art facility for conducting transportation operations research. The laboratory...

  19. Laboratory Directed Research and Development Program FY 2001

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Todd; Levy, Karin

    2002-03-15

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. This is the annual report on Laboratory Directed Research and Development (LDRD) program for FY01.

  20. Laboratory directed research and development program FY 1999

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Todd; Levy, Karin

    2000-03-08

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. This is the annual report on Laboratory Directed Research and Development (LDRD) program for FY99.

  1. Lunar laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Keaton, P.W.; Duke, M.B.

    1986-01-01

    An international research laboratory can be established on the Moon in the early years of the 21st Century. It can be built using the transportation system now envisioned by NASA, which includes a space station for Earth orbital logistics and orbital transfer vehicles for Earth-Moon transportation. A scientific laboratory on the Moon would permit extended surface and subsurface geological exploration; long-duration experiments defining the lunar environment and its modification by surface activity; new classes of observations in astronomy; space plasma and fundamental physics experiments; and lunar resource development. The discovery of a lunar source for propellants may reduce the cost of constructing large permanent facilities in space and enhance other space programs such as Mars exploration. 29 refs.

  2. Virtual Laboratories

    CERN Document Server

    Hut, P

    2006-01-01

    At the frontier of most areas in science, computer simulations play a central role. The traditional division of natural science into experimental and theoretical investigations is now completely outdated. Instead, theory, simulation, and experimentation form three equally essential aspects, each with its own unique flavor and challenges. Yet, education in computational science is still lagging far behind, and the number of text books in this area is minuscule compared to the many text books on theoretical and experimental science. As a result, many researchers still carry out simulations in a haphazard way, without properly setting up the computational equivalent of a well equipped laboratory. The art of creating such a virtual laboratory, while providing proper extensibility and documentation, is still in its infancy. A new approach is described here, Open Knowledge, as an extension of the notion of Open Source software. Besides open source code, manuals, and primers, an open knowledge project provides simul...

  3. Laboratory investigations

    International Nuclear Information System (INIS)

    Our task is to design mined-repository systems that will adequately secure high-level nuclear waste for at least 10,000 yr and that will be mechanically stable for 50 to 100-yr periods of retrievability during which mistakes could be corrected and a valuable source of energy could be reclaimed, should national policy on the reprocessing of spent fuel ever change. The only credible path for the escape of radionuclides from the repository to the biosphere is through ground-water, and in hard rock, bulk permeability is largely governed by natural and artificial fracture systems. Catastrophic failure of an excavation in hard rock is likely to occur at the weakest links - the discontinuities in the rock mass that is perturbed first by mining and then by radiogenic heating. The laboratory can contribute precise measurements of the pertinent thermomechanical, hydrological and chemical properties and improve our understanding of the fundamental processes through careful experiments under well controlled conditions that simulate the prototype environment. Thus laboratory investigations are necessary, but they are not sufficient, for conventional sample sizes are small relative to natural defects like joints - i.e., the rock mass is not a continuum - and test durations are short compared to those that predictive modeling must take into account. Laboratory investigators can contribute substantially more useful data if they are provided facilities for testing large specimens(say one cubic meter) and for creep testing of all candidate host rocks. Even so, extrapolations of laboratory data to the field in neither space nor time are valid without the firm theoretical foundations yet to be built. Meanwhile in-situ measurements of structure-sensitive physical properties and access to direct observations of rock-mass character will be absolutely necessary

  4. Culham Laboratory

    International Nuclear Information System (INIS)

    The report contains summaries of work carried out under the following headings: fusion research experiments; U.K. contribution to the JET project; supporting studies; theoretical plasma physics, computational physics and computing; fusion reactor studies; engineering and technology; contract research; external relations; staff, finance and services. Appendices cover main characteristics of Culham fusion experiments, staff, extra-mural projects supported by Culham Laboratory, and a list of papers written by Culham staff. (U.K.)

  5. Ethics in biotechnology and biosecurity

    Directory of Open Access Journals (Sweden)

    S Jameel

    2011-01-01

    Full Text Available Great advances in technology produce unique challenges. Every technology also has a dual use, which needs to be understood and managed to extract maximum benefits for mankind and the development of civilization. The achievements of physicists in the mid-20th century resulted in the nuclear technology, which gave us the destructive power of the atomic bomb as also a source of energy. Towards the later part of the 20th century, information technology empowered us with fast, easy and cheap access to information, but also led to intrusions into our privacy. Today, biotechnology is yielding life- saving and life-enhancing advances at a fast pace. But, the same tools can also give rise to fiercely destructive forces. How do we construct a security regime for biology? What have we learnt from the management of earlier technological advances? How much information should be in the public domain? Should biology, or more broadly science, be regulated? Who should regulate it? These and many other ethical questions need to be addressed.

  6. 生物安全性的不换水对虾养殖系统%Biosecure Zero-Water Exchange Shrimp Production Systems

    Institute of Scientific and Technical Information of China (English)

    Prud.,GD

    2000-01-01

    reduced, perhaps to zero, in many instances. This paper describes research findings supporting the concept of biosecure zero-water-exchange shrimp maturation/reproduction and hatchery/growout systems.

  7. The law of biosecurity under the boarding of the discourse ethics A lei de biossegurança sob a abordagem da ética discursiva

    Directory of Open Access Journals (Sweden)

    Simone Vinhas de Oliveira

    2007-12-01

    Full Text Available The biotechnology activity indicates a perspective to social and ecosystems modifications with improvidence about the results of these alterations. This involves ethical-legal topics, therefore, denotes risks for the contemporary society. The creation of public spaces with popular participation means a procedural proposal of control the possible imposes of the biotechnological activity and intend suppress the temerity. In this way, the discoursive ethics represent a key part of a project of democratic radicalization for which they are valid and accepted norms as universal state, this will in the biotechnological development - Universal Principle. And this will, as a rational will defined by the intersubjectiv of the communicative rationality, will only follow a norm if it will be universal in the measure and all the sectors interested in the biotechnological development to participate of the speeches - Principle of the Speech. For Habermas, the grounded discoursive norms make to be valid for two topics: the knowledge of something that exist in each moment and the every one interest, and also the general will that learned, without pressure, the will of everyone. With all those fundaments, it is able to have thoughts about the effect of the Biosecurity Law - the creation of one discretionary power to regulate the biotechnology activities thought CTNBio and the absence of regulation of the CNBS. These facts are asymmetric for the actual democratic stander and make unable the process of democratic radicalization.A atividade biotecnologia indica uma perspectiva de modificação social e de ecossistemas com uma imprevisão sobre os resultados dessas alterações. Isso toca em questões ético-jurídicas, pois, denota riscos para as sociedades contemporâneas. A criação de espaços públicos de participação popular significa uma proposta procedimental de controle dos possíveis abusos da atividade biotecnológica e a pretensa coibição das

  8. Biosecurity in public and private office A biossegurança nos consultórios públicos e particulares

    Directory of Open Access Journals (Sweden)

    Artênio José Isper Garbin

    2005-06-01

    Full Text Available Biosecurity is currently a concern for all health-related services, including dentistry, since infection control has a relevant importance. In dental practice, health-related occupations have contact with a great number of individuals who are potentially capable to transmit pathogens. This study comprised a descriptive evaluation of the universal precaution measures for infection control adopted by dental practitioners working at public and private offices in the city of Araçatuba, SP. Data collection was performed by a quiz with questions about individual and collective protection equipments. The results showed that the use of caps was reported by 55% of the professionals working at the public sector and 90% for the private sector. The use of masks and gloves was reported by all professionals surveyed; nevertheless, glove change between patients was not reported by 40% of professionals working at the public sector. There were more flaws in public offices as to the use of protective barriers, since except for the use of gloves, gowns and masks, the frequency of use of those barriers was smaller than at private offices.A biossegurança, atualmente, é uma preocupação de todos os serviços relacionados à saúde, neles inclui-se a odontologia, visto que o controle de infecção é de importância relevante. Na prática odontológica, as profissões de saúde têm contato com grande número de indivíduos que podem ser potencialmente capazes de transmitir patógenos. O objetivo do presente estudo foi uma avaliação descritiva da aplicação de medidas de precaução universal para controle de infecção entre cirurgiões-dentistas que atuam em consultórios públicos e particulares do Município de Araçatuba/SP. A coleta de dados foi realizada através de questionários contendo perguntas sobre equipamento de proteção individual e coletiva. Os resultados mostram que o uso de gorro foi relatado por 55% dos profissionais que atuam no servi

  9. Rethinking and Reconstruction on Animal Welfare in Experiments of Bioscience%生命科学实验中动物福利问题的反思与重构——基于生态哲学视角

    Institute of Scientific and Technical Information of China (English)

    朱玉芳

    2011-01-01

    针对目前生命科学实验中学生排斥使用实验动物的现象,反思并分析了过度关注动物福利的原因,并在解读生态哲学思想的基础上重构了实验中动物福利问题,旨在为高校的生命科学实验的顺利进行提供启示和借鉴.%At present,according to the phenomenon that students reject experimenting on animal in experiments of bioscience.the article reflects on and analyses the reasons for paying excessive attention to animal welfare,and on the basis of interpreting ecological philosophy,it rebuild the view of animal welfare in experiment,aiming at providing enlightenment and experience for carrying on biological science experiment successfully in college.

  10. Physical Sciences Laboratory (PSL)

    Data.gov (United States)

    Federal Laboratory Consortium — PNNL's Physical Sciences Laboratory (PSL) houses 22 research laboratories for conducting a wide-range of research including catalyst formulation, chemical analysis,...

  11. Bio Engineering Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Description/History: Chemistry and biology laboratories The Bio Engineering Laboratory (BeL) is theonly full spectrum biotechnology capability within the Department...

  12. Distributed Energy Technology Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Distributed Energy Technologies Laboratory (DETL) is an extension of the power electronics testing capabilities of the Photovoltaic System Evaluation Laboratory...

  13. FOOTWEAR PERFORMANCE LABORATORY

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory provides biomechanical and physical analyses for both military and commercial footwear. The laboratory contains equipment that is integral to the us...

  14. Theme: Laboratory Facilities Improvement.

    Science.gov (United States)

    Miller, Glen M.; And Others

    1993-01-01

    Includes "Laboratory Facilities Improvement" (Miller); "Remodeling Laboratories for Agriscience Instruction" (Newman, Johnson); "Planning for Change" (Mulcahy); "Laboratory Facilities Improvement for Technology Transfer" (Harper); "Facilities for Agriscience Instruction" (Agnew et al.); "Laboratory Facility Improvement" (Boren, Dwyer); and…

  15. Biomedical laboratories: architecture and radioprotection principles; Laboratorios biomedicos: arquitetura e principios de radioprotecao

    Energy Technology Data Exchange (ETDEWEB)

    Lapa, Renata [Fundacao Inst. Oswaldo Cruz (CIBio/FIOCRUZ), Rio de Janeiro, RJ (Brazil). Comissao Interna de Biosseguranca; Salgado, Monica Santos [Universidade Federal do Rio de Janeiro (PROARQ/FAU/UFRJ), RJ (Brazil). Fac. de Arquitetura e Urbanismo. Programa de Pos-Graduacao em Arquitetura; Vieira, Valeria Michielin [Universidade Federal do Rio de Janeiro (PROARQ/FAU/UFRJ), RJ (Brazil). Fac. de Arquitetura e Urbanismo. Programa de Pos-Graduacao em Arquitetura; Fundacao Inst. Oswaldo Cruz (FIOCRUZ), Rio de Janeiro, RJ (Brazil)

    2005-07-01

    In institutions where biological research are made and some technologies make use of radioisotope, the radiation protection is an issue of biosecurity for conceptual reasons. In the process of architectural design of Biomedical Laboratories, engineering and architecture reveal interfaces with other areas of knowledge and specific concepts. Exploring the role of architectural design in favor of personal and environmental protection in biological containment laboratories that handle non-sealed sources in research, the work discusses the triad that compose the principle of containment in health environments: best practices, protective equipment, physical facilities, with greater emphasis on the latter component. The shortcomings of the design process are reflected in construction and in use-operation and maintenance of these buildings, with direct consequences on the occupational health and safety, environmental and credibility of work processes. In this context, the importance of adoption of alternatives to improve the design process is confirmed, taking into account the early consideration of several variables involved and providing subsidies to the related laboratories . The research, conducted at FIOCRUZ - a Brazilian health institution, developed from the analysis of the participants in the architectural project, aiming at the formulation of design guidelines which could contribute to the rationalisation of this kind of building construction.

  16. Laboratory Directed Research and Development FY2011 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Craig, W; Sketchley, J; Kotta, P

    2012-03-22

    A premier applied-science laboratory, Lawrence Livermore National Laboratory (LLNL) has earned the reputation as a leader in providing science and technology solutions to the most pressing national and global security problems. The LDRD Program, established by Congress at all DOE national laboratories in 1991, is LLNL's most important single resource for fostering excellent science and technology for today's needs and tomorrow's challenges. The LDRD internally directed research and development funding at LLNL enables high-risk, potentially high-payoff projects at the forefront of science and technology. The LDRD Program at Livermore serves to: (1) Support the Laboratory's missions, strategic plan, and foundational science; (2) Maintain the Laboratory's science and technology vitality; (3) Promote recruiting and retention; (4) Pursue collaborations; (5) Generate intellectual property; and (6) Strengthen the U.S. economy. Myriad LDRD projects over the years have made important contributions to every facet of the Laboratory's mission and strategic plan, including its commitment to nuclear, global, and energy and environmental security, as well as cutting-edge science and technology and engineering in high-energy-density matter, high-performance computing and simulation, materials and chemistry at the extremes, information systems, measurements and experimental science, and energy manipulation. A summary of each project was submitted by the principal investigator. Project summaries include the scope, motivation, goals, relevance to DOE/NNSA and LLNL mission areas, the technical progress achieved in FY11, and a list of publications that resulted from the research. The projects are: (1) Nuclear Threat Reduction; (2) Biosecurity; (3) High-Performance Computing and Simulation; (4) Intelligence; (5) Cybersecurity; (6) Energy Security; (7) Carbon Capture; (8) Material Properties, Theory, and Design; (9) Radiochemistry; (10) High

  17. Biossegurança e odontologia: crenças e atitudes de graduandos sobre o controle da infecção cruzada Biosecurity and dentistry: beliefs and attitudes among dental students regarding infection control

    Directory of Open Access Journals (Sweden)

    Camila Pinelli

    2011-06-01

    Full Text Available Este estudo teve o objetivo de investigar as percepções de graduandos de Odontologia sobre a fidelidade às diretrizes de biossegurança e acerca do preservar-se. Nove questões abertas, que abordaram aspectos de interesse para o tema, foram aplicadas em entrevista com 14 acadêmicos, que realizavam atendimento odontológico de pacientes da Faculdade de Odontologia de Araraquara da Unesp. Utilizou-se a metodologia de pesquisa qualitativa e a estratégia metodológica para análise das entrevistas foi a Discurso do Sujeito Coletivo (DSC. Três figuras metodológicas foram obtidas, sendo ideias-centrais, expressões-chave e o DSC propriamente dito. A análise dos discursos permitiu avaliar a fala natural da coletividade. Verificou-se a adesão dos entrevistados aos protocolos de biossegurança, embora houvesse a queixa de que, na rotina diária, as precauções fossem negligenciadas por não serem muito práticas. Entre as medidas de proteção individual e coletiva, rotineiramente utilizadas, foram apontados o uso de Equipamento de Proteção Individual (EPI e as barreiras protetoras, bem como as atividades de desinfecção e esterilização. O risco de contágio foi visto por alguns com pavor e por outros com total indiferença porque acreditavam ser algo do qual é possível de se ter controle por meio da adesão às precauções padrão. Entre as doenças de maior preocupação, a aids e as hepatites B e C foram as mais temidas. Diante do discurso obtido, salienta-se a necessidade de se aperfeiçoar as estratégias educacionais, com intuito de motivar a fiel adesão às normas de biossegurança, essenciais no trato de pacientes odontológicos.The aim of the present study was to investigate dental students' perceptions in relation to adherence to Biosecurity guidelines and self-preservation. Nine open questions that approached aspects regarding the issue were asked in interview to 14 dental students who assisted dental patients at the

  18. Bioética, violência e desigualdade: as biociências e a constituição do biopoder Bioethics, violence and inequality: the biosciences and the conquest of biopower

    Directory of Open Access Journals (Sweden)

    Hélder Boska de Moraes Sarmento

    2008-12-01

    Full Text Available A sociedade contemporânea está atravessada por contradições e paradoxos, dentre os quais vale destacar a relação entre a alta tecnologia e, a pior situação humana, a miséria. Resultado das escolhas éticas e políticas desta era tecnológica, vive-se em situações de fronteira, nas quais as biociências desempenham papel central, tanto no volume de conhecimentos gerados, como na utilização de seus resultados, que, sem controle social, ampliam desigualdades. O objetivo deste artigo é demonstrar o quanto as biociências articulam-se com o desenvolvimento científico dos países inovadores de tecnologia, criando uma nova relação de poder, violento e desigual para os que apenas a consomem, denominado de biopoder. Daí a necessidade de uma bioética crítica capaz de empreender reflexões sobre os procedimentos técnicos, os fundamentos da atividade científica, sua aplicabilidade e relação com o mercado, oportunizando uma 'ponte' na tomada de decisões para que a própria ciência não se torne um obstáculo à democracia.Contemporary society is rife with contradictions and paradoxes, among which stand out the relationship between high technology and the worst human situation, poverty. The result of ethical and political choices of this technological era, we experience frontier situations, in which the biosciences play a central role, both in the volume of knowledge generated, as well as in the use of their results which, without social control, broaden inequalities. The objective of this article is to demonstrate the degree to which the biosciences are articulated with the scientific development of the countries that innovate technologies, creating a new relationship of power, which is violent and unequal for those who only consume, denominated biopower. This creates a need for a critical bioethics that is capable of reflecting on the technical procedures, the bases of scientific activity and their applicability and relation with

  19. An undergraduate laboratory activity on molecular dynamics simulations.

    Science.gov (United States)

    Spitznagel, Benjamin; Pritchett, Paige R; Messina, Troy C; Goadrich, Mark; Rodriguez, Juan

    2016-03-01

    Vision and Change [AAAS, 2011] outlines a blueprint for modernizing biology education by addressing conceptual understanding of key concepts, such as the relationship between structure and function. The document also highlights skills necessary for student success in 21st century Biology, such as the use of modeling and simulation. Here we describe a laboratory activity that allows students to investigate the dynamic nature of protein structure and function through the use of a modeling technique known as molecular dynamics (MD). The activity takes place over two lab periods that are 3 hr each. The first lab period unpacks the basic approach behind MD simulations, beginning with the kinematic equations that all bioscience students learn in an introductory physics course. During this period students are taught rudimentary programming skills in Python while guided through simple modeling exercises that lead up to the simulation of the motion of a single atom. In the second lab period students extend concepts learned in the first period to develop skills in the use of expert MD software. Here students simulate and analyze changes in protein conformation resulting from temperature change, solvation, and phosphorylation. The article will describe how these activities can be carried out using free software packages, including Abalone and VMD/NAMD. © 2016 by The International Union of Biochemistry and Molecular Biology, 44:130-139, 2016. PMID:26751047

  20. Laboratory Directed Research and Development Program FY2004

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Todd C.

    2005-03-22

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Berkeley Lab's research and the Laboratory Directed Research and Development (LDRD) program support DOE's Strategic Goals that are codified in DOE's September 2003 Strategic Plan, with a primary focus on Advancing Scientific Understanding. For that goal, the Fiscal Year (FY) 2004 LDRD projects support every one of the eight strategies described in the plan. In addition, LDRD efforts support the goals of Investing in America's Energy Future (six of the fourteen strategies), Resolving the Environmental Legacy (four of the eight strategies), and Meeting National Security Challenges (unclassified fundamental research that supports stockpile safety and nonproliferation programs). The LDRD supports Office of Science strategic plans, including the 20 year Scientific Facilities Plan and the draft Office of Science Strategic Plan. The research also

  1. Establishing a laboratory network of influenza diagnosis in Indonesia: an experience from the avian flu (H5N1 outbreak

    Directory of Open Access Journals (Sweden)

    Setiawaty V

    2012-08-01

    Full Text Available Vivi Setiawaty, Krisna NA Pangesti, Ondri D SampurnoNational Institute of Health Research and Development, Ministry of Health, the Republic of Indonesia, Jakarta, IndonesiaAbstract: Indonesia has been part of the global influenza surveillance since the establishment of a National Influenza Center (NIC at the National Institute of Health Research and Development (NIHRD by the Indonesian Ministry of Health in 1975. When the outbreak of avian influenza A (H5N1 occurred, the NIC and US Naval Medical Research Unit 2 were the only diagnostic laboratories equipped for etiology confirmation. The large geographical area of the Republic of Indonesia poses a real challenge to provide prompt and accurate diagnosis nationally. This was the main reason to establish a laboratory network for H5N1 diagnosis in Indonesia. Currently, 44 laboratories have been included in the network capable of performing polymerase chain reaction testing for influenza A. Diagnostic equipment and standard procedures of biosafety and biosecurity of handling specimens have been adopted largely from World Health Organization recommendations.Keywords: influenza, laboratory, networking

  2. Lincoln Laboratory Grid

    Data.gov (United States)

    Federal Laboratory Consortium — The Lincoln Laboratory Grid (LLGrid) is an interactive, on-demand parallel computing system that uses a large computing cluster to enable Laboratory researchers to...

  3. NASA Space Radiation Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The NASA Space Radiation Laboratory (NSRL) at Brookhaven National Laboratory is a NASA funded facility, delivering heavy ion beams to a target area where scientists...

  4. Laboratory-acquired brucellosis

    DEFF Research Database (Denmark)

    Fabiansen, C.; Knudsen, J.D.; Lebech, A.M.

    2008-01-01

    Brucellosis is a rare disease in Denmark. We describe one case of laboratory-acquired brucellosis from an index patient to a laboratory technician following exposure to an infected blood culture in a clinical microbiology laboratory Udgivelsesdato: 2008/6/9......Brucellosis is a rare disease in Denmark. We describe one case of laboratory-acquired brucellosis from an index patient to a laboratory technician following exposure to an infected blood culture in a clinical microbiology laboratory Udgivelsesdato: 2008/6/9...

  5. Communication and computing technology in biocontainment laboratories using the NEIDL as a model.

    Science.gov (United States)

    McCall, John; Hardcastle, Kath

    2014-07-01

    The National Emerging Infectious Diseases Laboratories (NEIDL), Boston University, is a globally unique biocontainment research facility housing biosafety level 2 (BSL-2), BSL-3, and BSL-4 laboratories. Located in the BioSquare area at the University's Medical Campus, it is part of a national network of secure facilities constructed to study infectious diseases of major public health concern. The NEIDL allows for basic, translational, and clinical phases of research to be carried out in a single facility with the overall goal of accelerating understanding, treatment, and prevention of infectious diseases. The NEIDL will also act as a center of excellence providing training and education in all aspects of biocontainment research. Within every detail of NEIDL operations is a primary emphasis on safety and security. The ultramodern NEIDL has required a new approach to communications technology solutions in order to ensure safety and security and meet the needs of investigators working in this complex building. This article discusses the implementation of secure wireless networks and private cloud computing to promote operational efficiency, biosecurity, and biosafety with additional energy-saving advantages. The utilization of a dedicated data center, virtualized servers, virtualized desktop integration, multichannel secure wireless networks, and a NEIDL-dedicated Voice over Internet Protocol (VoIP) network are all discussed. PMID:24535887

  6. [Establishment of Quality Control System of Nucleic Acid Detection for Ebola Virus in Sierra Leone-China Friendship Biological Safety Laboratory].

    Science.gov (United States)

    Wang, Qin; Zhang, Yong; Nie, Kai; Wang, Huanyu; Du, Haijun; Song, Jingdong; Xiao, Kang; Lei, Wenwen; Guo, Jianqiang; Wei, Hejiang; Cai, Kun; Wang, Yanhai; Wu, Jiang; Gerald, Bangura; Kamara, Idrissa Laybohr; Liang, Mifang; Wu, Guizhen; Dong, Xiaoping

    2016-03-01

    The quality control process throughout the Ebola virus nucleic acid detection in Sierra Leone-China Friendship Biological Safety Laboratory (SLE-CHN Biosafety Lab) was described in detail, in order to comprehensively display the scientific, rigorous, accurate and efficient practice in detection of Ebola virus of first batch detection team in SLE-CHN Biosafety Lab. Firstly, the key points of laboratory quality control system was described, including the managements and organizing, quality control documents and information management, instrument, reagents and supplies, assessment, facilities design and space allocation, laboratory maintenance and biosecurity. Secondly, the application of quality control methods in the whole process of the Ebola virus detection, including before the test, during the test and after the test, was analyzed. The excellent and professional laboratory staffs, the implementation of humanized management are the cornerstone of the success; High-level biological safety protection is the premise for effective quality control and completion of Ebola virus detection tasks. And professional logistics is prerequisite for launching the laboratory diagnosis of Ebola virus. The establishment and running of SLE-CHN Biosafety Lab has landmark significance for the friendship between Sierra Leone and China, and the lab becomes the most important base for Ebola virus laboratory testing in Sierra Leone.

  7. [Establishment of Quality Control System of Nucleic Acid Detection for Ebola Virus in Sierra Leone-China Friendship Biological Safety Laboratory].

    Science.gov (United States)

    Wang, Qin; Zhang, Yong; Nie, Kai; Wang, Huanyu; Du, Haijun; Song, Jingdong; Xiao, Kang; Lei, Wenwen; Guo, Jianqiang; Wei, Hejiang; Cai, Kun; Wang, Yanhai; Wu, Jiang; Gerald, Bangura; Kamara, Idrissa Laybohr; Liang, Mifang; Wu, Guizhen; Dong, Xiaoping

    2016-03-01

    The quality control process throughout the Ebola virus nucleic acid detection in Sierra Leone-China Friendship Biological Safety Laboratory (SLE-CHN Biosafety Lab) was described in detail, in order to comprehensively display the scientific, rigorous, accurate and efficient practice in detection of Ebola virus of first batch detection team in SLE-CHN Biosafety Lab. Firstly, the key points of laboratory quality control system was described, including the managements and organizing, quality control documents and information management, instrument, reagents and supplies, assessment, facilities design and space allocation, laboratory maintenance and biosecurity. Secondly, the application of quality control methods in the whole process of the Ebola virus detection, including before the test, during the test and after the test, was analyzed. The excellent and professional laboratory staffs, the implementation of humanized management are the cornerstone of the success; High-level biological safety protection is the premise for effective quality control and completion of Ebola virus detection tasks. And professional logistics is prerequisite for launching the laboratory diagnosis of Ebola virus. The establishment and running of SLE-CHN Biosafety Lab has landmark significance for the friendship between Sierra Leone and China, and the lab becomes the most important base for Ebola virus laboratory testing in Sierra Leone. PMID:27396166

  8. Laboratory of Chemical Physics

    Data.gov (United States)

    Federal Laboratory Consortium — Current research in the Laboratory of Chemical Physics is primarily concerned with experimental, theoretical, and computational problems in the structure, dynamics,...

  9. Embedded Processor Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Embedded Processor Laboratory provides the means to design, develop, fabricate, and test embedded computers for missile guidance electronics systems in support...

  10. COGNITIVE PERFORMANCE LABORATORY

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory conducts basic and applied human research studies to characterize cognitive performance as influenced by militarily-relevant contextual and physical...

  11. Optical Remote Sensing Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Optical Remote Sensing Laboratory deploys rugged, cutting-edge electro-optical instrumentation for the collection of various event signatures, with expertise in...

  12. Intelligent Optics Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Intelligent Optics Laboratory supports sophisticated investigations on adaptive and nonlinear optics; advancedimaging and image processing; ground-to-ground and...

  13. Environmental Microbiology Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Environmental Microbiology Laboratory, located in Bldg. 644 provides a dual-gas respirometer for measurement of oxygen consumption and carbon dioxide evolution...

  14. ANALYTICAL MICROBIOLOGY LABORATORY

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory contains equipment that performs a broad array of microbiological analyses for pathogenic and spoilage microorganisms. It performs challenge studies...

  15. Neural Systems Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — As part of the Electrical and Computer Engineering Department and The Institute for System Research, the Neural Systems Laboratory studies the functionality of the...

  16. Central Laboratories Services

    Data.gov (United States)

    Federal Laboratory Consortium — The TVA Central Laboratories Services is a comprehensive technical support center, offering you a complete range of scientific, engineering, and technical services....

  17. Tactical Systems Integration Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Tactical Systems Integration Laboratory is used to design and integrate computer hardware and software and related electronic subsystems for tactical vehicles....

  18. Virtual Training Devices Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Virtual Training Devices (VTD) Laboratory at the Life Cycle Software Engineering Center, Picatinny Arsenal, provides a software testing and support environment...

  19. FOOD SAFETY TESTING LABORATORY

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory develops screening assays, tests and modifies biosensor equipment, and optimizes food safety testing protocols for the military and civilian sector...

  20. Space Weather Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Space Weather Computational Laboratory is a Unix and PC based modeling and simulation facility devoted to research analysis of naturally occurring electrically...

  1. Composites Characterization Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The purpose of the Composites Characterization Laboratory is to investigate new and/or modified matrix materials and fibers for advanced composite applications both...

  2. Rapid Prototyping Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The ARDEC Rapid Prototyping (RP) Laboratory was established in December 1992 to provide low cost RP capabilities to the ARDEC engineering community. The Stratasys,...

  3. Engineered Natural Systems Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — With its pressure vessels that simulate the pressures and temperatures found deep underground, NETL’s Engineered Natural Systems Laboratory in Pittsburgh, PA, gives...

  4. [Theme: Using Laboratories.

    Science.gov (United States)

    Pritchard, Jack; Braker, Clifton

    1982-01-01

    Pritchard discusses the opportunities for applied learning afforded by laboratories. Braker describes the evaluation of cognitive, affective, and psychomotor skills in the agricultural mechanics laboratory. (SK)

  5. Vehicle Development Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Supports the development of prototype deployment platform vehicles for offboard countermeasure systems. DESCRIPTION: The Vehicle Development Laboratory is...

  6. Fuels Processing Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — NETL’s Fuels Processing Laboratory in Morgantown, WV, provides researchers with the equipment they need to thoroughly explore the catalytic issues associated with...

  7. Thermogravimetric Analysis Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — At NETL’s Thermogravimetric Analysis Laboratory in Morgantown, WV, researchers study how chemical looping combustion (CLC) can be applied to fossil energy systems....

  8. Biossegurança em uma unidade de terapia intensiva: a percepção da equipe de enfermagem Bioseguridad en una unidad de terapia intensiva: la percepción del equipo de enfermería Biosecurity in an intensive care unit: the nursing team perception

    Directory of Open Access Journals (Sweden)

    Chistina Feitoza Correa

    2007-06-01

    relación con la importancia de adoptar e implementar las medidas de bioseguridad y posibilidades de intervención para la adopción e implementación de medidas de bioseguridad. Se ha verificado que las normas de bioseguridad deben incluir las buenas prácticas, posibilitando alcanzar un ambiente laboral sin riesgos ocupacionales.The descriptive study having a qualitative approach aimed at: describing the biosecurity measures adopted by the nursing team during the attendance on an ICU identifying the perception of the nursing team about the importance of adopting and implementing biosecurity measures during the attendance and analyzing the possibilities to the team of implementing some biosecurity measures during the attendance. The data were obtained by means of the systematic observation and interviews with semi-structured script, carried out on an ICU where 29 nurses used to work. The thematic analysis of the interviews allowed identifying three categories: biosecurity measures adopted by the nurse team; perception of this team concerning the importance of adopting and implementing the biosecurity measures and the possibilities of intervention for the adoption and implementation of the biosecurity measures. It was verified that the biosecurity rules must include the good practices, making possible to reach a labor ambience with no occupational risks.

  9. The Composition of Cockfighting Immune System and the Management Measures with Bio-security System%斗鸡免疫系统组成及生物安全体系下的管理措施

    Institute of Scientific and Technical Information of China (English)

    秦巧梅; 张清峰

    2011-01-01

    Cockfighting has many unique and excellent traits. With the development of the cockfighting breeding and exploitation,scientific feeding and management is more important for cockfighting industry. In order to further develop the valuable resource,from preventing the disease to improving the immune response. The article describes the composition of the immune system and defense mechanism for poultry, and makes a suggestion for the feeding pattern with bio-security system of cockfighting.%斗鸡具有许多优良的独特性状,随着斗鸡的选育和开发利用的不断加强,科学饲养管理是斗鸡品种保护和产业壮大的重要环节.为了进一步开发这一珍贵资源,作者从预防疾病、提高免疫应答入手,针对禽类免疫系统的组成和防御机理进行了阐述,并提出现实中生物安全体系下斗鸡的饲养模式.

  10. Energy Materials Research Laboratory (EMRL)

    Data.gov (United States)

    Federal Laboratory Consortium — The Energy Materials Research Laboratory at the Savannah River National Laboratory (SRNL) creates a cross-disciplinary laboratory facility that lends itself to the...

  11. Laboratory directed research and development program FY 2003

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Todd

    2004-03-27

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. In FY03, Berkeley Lab was authorized by DOE to establish a funding ceiling for the LDRD program of $15.0 M, which equates to about 3.2% of Berkeley Lab's FY03 projected operating and capital equipment budgets. This funding level was provided to develop new scientific ideas and opportunities and allow the Berkeley Lab Director an opportunity to initiate new directions. Budget constraints limited available resources, however, so only $10.1 M was expended for operating and $0.6 M for capital equipment (2.4% of actual Berkeley Lab FY03 costs). In FY03, scientists submitted 168 proposals, requesting over $24.2 M in operating funding. Eighty-two projects were funded, with awards ranging from $45 K to $500 K. These projects are summarized in Table 1.

  12. Aircraft Fire Protection Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Navy Aircraft Protection Laboratory provides complete test support for all Navy air vehicle fire protection systems. The facility allows for the simulation of a...

  13. Energetics Laboratory Facilities

    Data.gov (United States)

    Federal Laboratory Consortium — These energetic materials laboratories are equipped with explosion proof hoods with blow out walls for added safety, that are certified for safe handling of primary...

  14. Laboratory of Biological Modeling

    Data.gov (United States)

    Federal Laboratory Consortium — The Laboratory of Biological Modeling is defined by both its methodologies and its areas of application. We use mathematical modeling in many forms and apply it to...

  15. Laboratory Demographics Lookup Tool

    Data.gov (United States)

    U.S. Department of Health & Human Services — This website provides demographic information about laboratories, including CLIA number, facility name and address, where the laboratory testing is performed, the...

  16. Building the Korogwe Laboratory

    DEFF Research Database (Denmark)

    Knudsen, Jakob; von Seidlein, Lorenz; Richard, Jean Pierre

    2011-01-01

    An illustrated description of the building of a biomedical research laboratory in Korogwe, Tanzania.......An illustrated description of the building of a biomedical research laboratory in Korogwe, Tanzania....

  17. Geological Services Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Researchers use computed tomography (CT) scanners at NETL’s Geological Services Laboratory in Morgantown, WV, to peer into geologic core samples to determine how...

  18. Clinical Laboratory Fee Schedule

    Data.gov (United States)

    U.S. Department of Health & Human Services — Outpatient clinical laboratory services are paid based on a fee schedule in accordance with Section 1833(h) of the Social Security Act. The clinical laboratory fee...

  19. Electro-Deposition Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The electro-deposition laboratory can electro-deposit various coatings onto small test samples and bench level prototypes. This facility provides the foundation for...

  20. Protective Systems Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory is a 40 by 28 by 9 foot facility that is equipped with tools for the development of various items of control technology related to the transmission...

  1. Moriah Wind System Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Purpose: The Moriah Wind System Laboratory provides in-service support for the more than 50 U.S. Navy, U.S. Coast Guard and Military Sealift Command ships on which...

  2. Aquatic Research Laboratory (ARL)

    Data.gov (United States)

    Federal Laboratory Consortium — Columbia River and groundwater well water sources are delivered to the Aquatic Research Laboratory (ARL), where these resources are used to conduct research on fish...

  3. FLEXIBLE FOOD PACKAGING LABORATORY

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory contains equipment to fabricate and test prototype packages of many types and sizes (e.g., bags, pouches, trays, cartons, etc.). This equipment can...

  4. Mechanical Testing Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — NETL’s Mechanical Testing Laboratory in Albany, OR, helps researchers investigate materials that can withstand the heat and pressure commonly found in fossil energy...

  5. High Bay Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory is a specially constructed facility with elevated (37 feet) ceilings and an overhead catwalk, and which is dedicated to research efforts in reducing...

  6. Space Systems Laboratory (SSL)

    Data.gov (United States)

    Federal Laboratory Consortium — The Space Systems Laboratory (SSL) is part of the Aerospace Engineering Department and A. James Clark School of Engineering at the University of Maryland in College...

  7. Eficacia de las medidas de bioseguridad en el control de microorganismos asociados a endometritis porcinas: Estudio preliminar Efficacy of biosecurity measures in the control of microorganisms associated to endometritis in sows: Preliminary study

    Directory of Open Access Journals (Sweden)

    JC Gómez

    2011-01-01

    ausencia de medidas que eviten la presencia de vectores y el establecimiento de estrictos protocolos de limpieza y desinfección.Biosecurity can be defined as all the applied measurements that take as a target to minimize the sanitary risks in a stock farm, and include measurements related to the facilities and the management. The efficacy of these measurements must be reflected in a decrease of the microorganism in different productive phases. A study was carried out to evaluate if the set of applied measurements influences the microbial uterine contamination after farrowing of healthy sows. Two swine farms were been completed about biosecurity measurements was completed and a microbiological study of uterine swabs of sows after the farrowing was carried out. A total of 60 animals were studied, and 27 (45%, 95% CI [33.3%, 56.7%] resulted positive. Significant differences between production and selection and multiplication farms were detected (OR = 3.44, IC 95%, 1.135-11.047. The colonization frequency was 65% CI [51.3%, 78.6%] and 35% CI [21%, 49%] in production and selection farm, respectively (P = 0.02. A total of 66 isolates were obtained, represented mainly by Staphylococcus spp. (33.33% and Aerococcus spp. (27.27%, although other species included in the genus Streptococcus (9.09%, Enterococcus (6.06% and Pseudomonas (4.55%, as well as different fungi species were also isolated. The frequency of isolation of different microorganisms was similar in both farms, with the exception of the genus Enterococcus that was not isolated in the production farm (P = 0.01. The questionnaire showed some differences in biosecurity measures in the selection and multiplication farm when it is compared to the production farm, which together with the increased uterine microbial contamination observed in the latter leads us to propose a preliminary hypothesis about the possible risk factors associated with this process, highlighting the absence of measures to avoid the presence of vectors

  8. Experiences with Remote Laboratories

    OpenAIRE

    Andrew Nafalski; Ozdemir Gol; Zorica Nedic; Jan Machotka; José M. M. Ferreira; Ingvar Gustavsson

    2010-01-01

    The paper reports on experiences of academics and students involved in using remote engineering laboratories both when students work individually or collaboratively with others on the experiments. Positives and negatives are highlighted and are contrasted with expectations of what the remote laboratories can bring into pedagogical environments. Recommendations and conclusions follow on how to better use the remote laboratories in teaching.

  9. Laboratory Activities in Israel

    Science.gov (United States)

    Mamlok-Naaman, Rachel; Barnea, Nitza

    2012-01-01

    Laboratory activities have long had a distinctive and central role in the science curriculum, and science educators have suggested that many benefits accrue from engaging students in science laboratory activities. Many research studies have been conducted to investigate the educational effectiveness of laboratory work in science education in…

  10. Good Laboratory Practice

    Science.gov (United States)

    Hadjicostas, Evsevios

    The principles of Good Laboratory Practice (GLP) in conjunction with the principles of Total Quality Management (see chapter 6) ensure the quality and reliability of the laboratory results, which in turn help to ensure the protection of the environment and human health and safety. A step further is the accreditation of laboratories to ISO 17025 (see chapter 2) to perform specified activities.

  11. Skylab mobile laboratory

    Science.gov (United States)

    Primeaux, G. R.; Larue, M. A.

    1975-01-01

    The Skylab mobile laboratory was designed to provide the capability to obtain necessary data on the Skylab crewmen 30 days before lift-off, within 1 hour after recovery, and until preflight physiological baselines were reattained. The mobile laboratory complex consisted of six laboratories that supported cardiovascular, metabolic, nutrition and endocrinology, operational medicine, blood, and microbiology experiments; a utility package; and two shipping containers. The objectives and equipment requirements of the Skylab mobile laboratory and the data acquisition systems are discussed along with processes such as permanently mounting equipment in the individual laboratories and methods of testing and transporting the units. The operational performance, in terms of amounts of data collected, and the concept of mobile laboratories for medical and scientific experiments are evaluated. The Skylab mobile laboratory succeeded in facilitating the data collection and sample preservation associated with the three Skylab manned flights.

  12. Personalized laboratory medicine

    DEFF Research Database (Denmark)

    Pazzagli, M.; Malentacchi, F.; Mancini, I.;

    2015-01-01

    diagnostic tools and expertise and commands proper state-of-the-art knowledge about Personalized Medicine and Laboratory Medicine in Europe, the joint Working Group "Personalized Laboratory Medicine" of the EFLM and ESPT societies compiled and conducted the Questionnaire "Is Laboratory Medicine ready...... for the era of Personalized Medicine?". 48 laboratories from 18 European countries participated at this survey. The answers of the participating Laboratory Medicine professionals indicate that they are aware that Personalized Medicine can represent a new and promising health model. Whereas they are aware...... that Laboratory Medicine should play a key role to support the implementation of Personalized Medicine in the clinical settings, the participants of this survey think that the current organization of the Laboratory Medicine needs additional/relevant implementations such as: 1. New technological Facilities...

  13. Heat Flux Instrumentation Laboratory (HFIL)

    Data.gov (United States)

    Federal Laboratory Consortium — Description: The Heat Flux Instrumentation Laboratory is used to develop advanced, flexible, thin film gauge instrumentation for the Air Force Research Laboratory....

  14. Optics/Optical Diagnostics Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Optics/Optical Diagnostics Laboratory supports graduate instruction in optics, optical and laser diagnostics and electro-optics. The optics laboratory provides...

  15. 9 CFR 161.1 - Statement of purpose; performance of accredited duties in different States.

    Science.gov (United States)

    2010-01-01

    ...) Animal health emergency management; and (ix) Animal health procedures, issues, and information resources... appropriate laboratory for testing with complete and accurate paperwork. (ix) Develop appropriate biosecurity...., caudal fold test). (xv) Develop appropriate biosecurity protocols, as well as cleaning and...

  16. Head Impact Laboratory (HIL)

    Data.gov (United States)

    Federal Laboratory Consortium — The HIL uses testing devices to evaluate vehicle interior energy attenuating (EA) technologies for mitigating head injuries resulting from head impacts during mine/...

  17. Shallow Water Acoustic Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Supports experimental research where high-frequency acoustic scattering and surface vibration measurements of fluid-loaded and non-fluid-loaded structures...

  18. Materials Behavior Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The purpose is to evaluate mechanical properties of materials including metals, intermetallics, metal-matrix composites, and ceramic-matrix composites under typical...

  19. Metallurgical Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The purpose is to increase basic knowledge of metallurgical processing for controlling the microstructure and mechanical properties of metallic aerospace alloys and...

  20. Laboratory Astrophysics White Paper

    Science.gov (United States)

    Brickhouse, Nancy; Federman, Steve; Kwong, Victor; Salama, Farid; Savin, Daniel; Stancil, Phillip; Weingartner, Joe; Ziurys, Lucy

    2006-01-01

    Laboratory astrophysics and complementary theoretical calculations are the foundations of astronomical and planetary research and will remain so for many generations to come. From the level of scientific conception to that of the scientific return, it is our understanding of the underlying processes that allows us to address fundamental questions regarding the origins and evolution of galaxies, stars, planetary systems, and life in the cosmos. In this regard, laboratory astrophysics is much like detector and instrument development at NASA and NSF; these efforts are necessary for the astronomical research being funded by the agencies. The NASA Laboratory Astrophysics Workshop met at the University of Nevada, Las Vegas (UNLV) from 14-16 February, 2006 to identify the current laboratory data needed to support existing and future NASA missions and programs in the Astrophysics Division of the Science Mission Directorate (SMD). Here we refer to both laboratory and theoretical work as laboratory astrophysics unless a distinction is necessary. The format for the Workshop involved invited talks by users of laboratory data, shorter contributed talks and poster presentations by both users and providers that highlighted exciting developments in laboratory astrophysics, and breakout sessions where users and providers discussed each others' needs and limitations. We also note that the members of the Scientific Organizing Committee are users as well as providers of laboratory data. As in previous workshops, the focus was on atomic, molecular, and solid state physics.

  1. Flying Electronic Warfare Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Provides NP-3D aircraft host platforms for Effectiveness of Navy Electronic Warfare Systems (ENEWS) Program antiship missile (ASM) seeker simulators used...

  2. High Temperature Materials Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The High Temperature Materials Lab provides the Navy and industry with affordable high temperature materials for advanced propulsion systems. Asset List: Arc Melter...

  3. Free Surface Hydrodynamics Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Investigates processes and interactions at the air-sea interface, and compares measurements to numerical simulations and field data. Typical phenomena of...

  4. Biochemical Neuroscience Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This biochemistry lab is set up for protein analysis using Western blot, enzyme linked immunosorbent assays, immunohistochemistry, and bead-based immunoassays. The...

  5. Applied Neuroscience Laboratory Complex

    Data.gov (United States)

    Federal Laboratory Consortium — Located at WPAFB, Ohio, the Applied Neuroscience lab researches and develops technologies to optimize Airmen individual and team performance across all AF domains....

  6. Virtual Reality Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Performs basic and applied research in interactive 3D computer graphics, including visual analytics, virtual environments, and augmented reality (AR). The...

  7. Argonne's Laboratory Computing Resource Center : 2005 annual report.

    Energy Technology Data Exchange (ETDEWEB)

    Bair, R. B.; Coghlan, S. C; Kaushik, D. K.; Riley, K. R.; Valdes, J. V.; Pieper, G. P.

    2007-06-30

    Argonne National Laboratory founded the Laboratory Computing Resource Center in the spring of 2002 to help meet pressing program needs for computational modeling, simulation, and analysis. The guiding mission is to provide critical computing resources that accelerate the development of high-performance computing expertise, applications, and computations to meet the Laboratory's challenging science and engineering missions. The first goal of the LCRC was to deploy a mid-range supercomputing facility to support the unmet computational needs of the Laboratory. To this end, in September 2002, the Laboratory purchased a 350-node computing cluster from Linux NetworX. This cluster, named 'Jazz', achieved over a teraflop of computing power (10{sup 12} floating-point calculations per second) on standard tests, making it the Laboratory's first terascale computing system and one of the fifty fastest computers in the world at the time. Jazz was made available to early users in November 2002 while the system was undergoing development and configuration. In April 2003, Jazz was officially made available for production operation. Since then, the Jazz user community has grown steadily. By the end of fiscal year 2005, there were 62 active projects on Jazz involving over 320 scientists and engineers. These projects represent a wide cross-section of Laboratory expertise, including work in biosciences, chemistry, climate, computer science, engineering applications, environmental science, geoscience, information science, materials science, mathematics, nanoscience, nuclear engineering, and physics. Most important, many projects have achieved results that would have been unobtainable without such a computing resource. The LCRC continues to improve the computational science and engineering capability and quality at the Laboratory. Specific goals include expansion of the use of Jazz to new disciplines and Laboratory initiatives, teaming with Laboratory infrastructure

  8. Distance and virtual laboratories

    NARCIS (Netherlands)

    Bauer, P.; Fedak, V.; Hajek, V.

    2007-01-01

    The paper deals with basic philosophy and structure of a remote controlled laboratory for experimentation in Electrical Engineering. The laboratory collects experiments from fields of Power Electronics, Electrical Machines, Electro-Mechanical and Motion Control Systems. The workbenches in the real l

  9. ELECTROPNEUMATIC AUTOMATION EDUCATIONAL LABORATORY

    OpenAIRE

    Dolgorukov, S. O.; National Aviation University; Roman, B. V.; National Aviation University

    2013-01-01

    The article reflects current situation in education regarding mechatronics learning difficulties. Com-plex of laboratory test benches on electropneumatic automation are considered as a tool in advancing through technical science. Course of laboratory works developed to meet the requirement of efficient and reliable way of practical skills acquisition is regarded the simplest way for students to learn the ba-sics of mechatronics.

  10. Biotechnology Laboratory Methods.

    Science.gov (United States)

    Davis, Robert H.; Kompala, Dhinakar S.

    1989-01-01

    Describes a course entitled "Biotechnology Laboratory" which introduces a variety of laboratory methods associated with biotechnology. Describes the history, content, and seven experiments of the course. The seven experiments are selected from microbiology and molecular biology, kinetics and fermentation, and downstream processing-bioseparations.…

  11. The Virtual Robotics Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Kress, R.L.; Love, L.J.

    1999-09-01

    The growth of the Internet has provided a unique opportunity to expand research collaborations between industry, universities, and the national laboratories. The Virtual Robotics Laboratory (VRL) is an innovative program at Oak Ridge National Laboratory (ORNL) that is focusing on the issues related to collaborative research through controlled access of laboratory equipment using the World Wide Web. The VRL will provide different levels of access to selected ORNL laboratory secondary education programs. In the past, the ORNL Robotics and Process Systems Division has developed state-of-the-art robotic systems for the Army, NASA, Department of Energy, Department of Defense, as well as many other clients. After proof of concept, many of these systems sit dormant in the laboratories. This is not out of completion of all possible research topics. but from completion of contracts and generation of new programs. In the past, a number of visiting professors have used this equipment for their own research. However, this requires that the professor, and possibly his/her students, spend extended periods at the laboratory facility. In addition, only a very exclusive group of faculty can gain access to the laboratory and hardware. The VRL is a tool that enables extended collaborative efforts without regard to geographic limitations.

  12. The Virtual Robotics Laboratory

    International Nuclear Information System (INIS)

    The growth of the Internet has provided a unique opportunity to expand research collaborations between industry, universities, and the national laboratories. The Virtual Robotics Laboratory (VRL) is an innovative program at Oak Ridge National Laboratory (ORNL) that is focusing on the issues related to collaborative research through controlled access of laboratory equipment using the World Wide Web. The VRL will provide different levels of access to selected ORNL laboratory equipment to outside universities, industrial researchers, and elementary and secondary education programs. In the past, the ORNL Robotics and Process Systems Division (RPSD) has developed state-of-the-art robotic systems for the Army, NASA, Department of Energy, Department of Defense, as well as many other clients. After proof of concept, many of these systems sit dormant in the laboratories. This is not out of completion of all possible research topics, but from completion of contracts and generation of new programs. In the past, a number of visiting professors have used this equipment for their own research. However, this requires that the professor, and possibly his students, spend extended periods at the laboratory facility. In addition, only a very exclusive group of faculty can gain access to the laboratory and hardware. The VRL is a tool that enables extended collaborative efforts without regard to geographic limitations

  13. NVLAP calibration laboratory program

    Energy Technology Data Exchange (ETDEWEB)

    Cigler, J.L.

    1993-12-31

    This paper presents an overview of the progress up to April 1993 in the development of the Calibration Laboratories Accreditation Program within the framework of the National Voluntary Laboratory Accreditation Program (NVLAP) at the National Institute of Standards and Technology (NIST).

  14. Quality in Teaching Laboratories.

    Science.gov (United States)

    Stubington, John F.

    1995-01-01

    Describes a Japanese process-oriented approach called KAIZEN for improving the quality of existing teaching laboratories. It provides relevant quality measurements and indicates how quality can be improved. Use of process criteria sidesteps the difficulty of defining quality for laboratory experiments and allows separation of student assessment…

  15. Argonne's Laboratory computing resource center : 2006 annual report.

    Energy Technology Data Exchange (ETDEWEB)

    Bair, R. B.; Kaushik, D. K.; Riley, K. R.; Valdes, J. V.; Drugan, C. D.; Pieper, G. P.

    2007-05-31

    Argonne National Laboratory founded the Laboratory Computing Resource Center (LCRC) in the spring of 2002 to help meet pressing program needs for computational modeling, simulation, and analysis. The guiding mission is to provide critical computing resources that accelerate the development of high-performance computing expertise, applications, and computations to meet the Laboratory's challenging science and engineering missions. In September 2002 the LCRC deployed a 350-node computing cluster from Linux NetworX to address Laboratory needs for mid-range supercomputing. This cluster, named 'Jazz', achieved over a teraflop of computing power (10{sup 12} floating-point calculations per second) on standard tests, making it the Laboratory's first terascale computing system and one of the 50 fastest computers in the world at the time. Jazz was made available to early users in November 2002 while the system was undergoing development and configuration. In April 2003, Jazz was officially made available for production operation. Since then, the Jazz user community has grown steadily. By the end of fiscal year 2006, there were 76 active projects on Jazz involving over 380 scientists and engineers. These projects represent a wide cross-section of Laboratory expertise, including work in biosciences, chemistry, climate, computer science, engineering applications, environmental science, geoscience, information science, materials science, mathematics, nanoscience, nuclear engineering, and physics. Most important, many projects have achieved results that would have been unobtainable without such a computing resource. The LCRC continues to foster growth in the computational science and engineering capability and quality at the Laboratory. Specific goals include expansion of the use of Jazz to new disciplines and Laboratory initiatives, teaming with Laboratory infrastructure providers to offer more scientific data management capabilities, expanding Argonne staff

  16. [Accreditation of medical laboratories].

    Science.gov (United States)

    Horváth, Andrea Rita; Ring, Rózsa; Fehér, Miklós; Mikó, Tivadar

    2003-07-27

    In Hungary, the National Accreditation Body was established by government in 1995 as an independent, non-profit organization, and has exclusive rights to accredit, amongst others, medical laboratories. The National Accreditation Body has two Specialist Advisory Committees in the health care sector. One is the Health Care Specialist Advisory Committee that accredits certifying bodies, which deal with certification of hospitals. The other Specialist Advisory Committee for Medical Laboratories is directly involved in accrediting medical laboratory services of health care institutions. The Specialist Advisory Committee for Medical Laboratories is a multidisciplinary peer review group of experts from all disciplines of in vitro diagnostics, i.e. laboratory medicine, microbiology, histopathology and blood banking. At present, the only published International Standard applicable to laboratories is ISO/IEC 17025:1999. Work has been in progress on the official approval of the new ISO 15189 standard, specific to medical laboratories. Until the official approval of the International Standard ISO 15189, as accreditation standard, the Hungarian National Accreditation Body has decided to progress with accreditation by formulating explanatory notes to the ISO/IEC 17025:1999 document, using ISO/FDIS 15189:2000, the European EC4 criteria and CPA (UK) Ltd accreditation standards as guidelines. This harmonized guideline provides 'explanations' that facilitate the application of ISO/IEC 17025:1999 to medical laboratories, and can be used as a checklist for the verification of compliance during the onsite assessment of the laboratory. The harmonized guideline adapted the process model of ISO 9001:2000 to rearrange the main clauses of ISO/IEC 17025:1999. This rearrangement does not only make the guideline compliant with ISO 9001:2000 but also improves understanding for those working in medical laboratories, and facilitates the training and education of laboratory staff. With the

  17. The Gran Sasso Laboratory

    Science.gov (United States)

    Votano, L.

    2012-09-01

    The Gran Sasso underground laboratory is one of the four national laboratories run by the INFN (Istituto Nazionale di Fisica Nucleare). It is located under the Gran Sasso massif, in central Italy, between the cities of L'Aquila and Teramo, 120 km far from Rome. It is the largest underground laboratory for astroparticle physics in the world and the most advanced in terms of complexity and completeness of its infrastructures. The scientific program at the Gran Sasso National Laboratories (Laboratori Nazionali del Gran Sasso, LNGS)is mainly focused on astroparticle, particle and nuclear physics. The laboratory presently hosts many experiments as well as R&D activities, including world-leading research in the fields of solar neutrinos, accelerator neutrinos (CNGS neutrino beam from CERN to Gran Sasso), dark matter, neutrinoless double-beta decay and nuclear cross-section of astrophysical interest. Associate sciences like earth physics, biology and fundamental physics complement the activities. The laboratory is operated as an international science facility and hosts experiments whose scientific merit is assessed by an international advisory Scientific Committee. A review of the main experiments carried out at LNGS will be given, together with the most recent and relevant scientific results achieved.

  18. Simula Research Laboratory

    CERN Document Server

    Tveito, Aslak

    2010-01-01

    The Simula Research Laboratory, located just outside Oslo in Norway, is rightly famed as a highly successful research facility, despite being, at only eight years old, a very young institution. This fascinating book tells the history of Simula, detailing the culture and values that have been the guiding principles of the laboratory throughout its existence. Dedicated to tackling scientific challenges of genuine social importance, the laboratory undertakes important research with long-term implications in networks, computing and software engineering, including specialist work in biomedical comp

  19. Digital signal processing laboratory

    CERN Document Server

    Kumar, B Preetham

    2011-01-01

    INTRODUCTION TO DIGITAL SIGNAL PROCESSING Brief Theory of DSP ConceptsProblem SolvingComputer Laboratory: Introduction to MATLAB®/SIMULINK®Hardware Laboratory: Working with Oscilloscopes, Spectrum Analyzers, Signal SourcesDigital Signal Processors (DSPs)ReferencesDISCRETE-TIME LTI SIGNALS AND SYSTEMS Brief Theory of Discrete-Time Signals and SystemsProblem SolvingComputer Laboratory: Simulation of Continuous Time and Discrete-Time Signals and Systems ReferencesTIME AND FREQUENCY ANALYSIS OF COMMUNICATION SIGNALS Brief Theory of Discrete-Time Fourier Transform (DTFT), Discrete Fourier Transform

  20. Specialized Laboratory Information Systems.

    Science.gov (United States)

    Dangott, Bryan

    2016-03-01

    Some laboratories or laboratory sections have unique needs that traditional anatomic and clinical pathology systems may not address. A specialized laboratory information system (LIS), which is designed to perform a limited number of functions, may perform well in areas where a traditional LIS falls short. Opportunities for specialized LISs continue to evolve with the introduction of new testing methodologies. These systems may take many forms, including stand-alone architecture, a module integrated with an existing LIS, a separate vendor-supplied module, and customized software. This article addresses the concepts underlying specialized LISs, their characteristics, and in what settings they are found. PMID:26851663

  1. Rethinking Laboratory Notebooks

    DEFF Research Database (Denmark)

    Klokmose, Clemens Nylandsted; Zander, Pär-Ola

    2010-01-01

    We take digitalization of laboratory work practice as a challenging design domain to explore. There are obvious drawbacks with the use of paper instead of ICT in the collaborative writing that takes place in laboratory notebooks; yet paper persist in being the most common solution. The ultimate aim...... with our study is to produce design relevant knowledge that can envisage an ICT solution that keeps as many advantages of paper as possible, but with the strength of electronic laboratory notebooks as well. Rather than assuming that users are technophobic and unable to appropriate state of the art...

  2. Satellite Control Laboratory

    DEFF Research Database (Denmark)

    Wisniewski, Rafal; Bak, Thomas

    2001-01-01

    The Satellite Laboratory at the Department of Control Engineering of Aalborg University (SatLab) is a dynamic motion facility designed for analysis and test of micro spacecraft. A unique feature of the laboratory is that it provides a completely gravity-free environment. A test spacecraft...... of the laboratory is to conduct dynamic tests of the control and attitude determination algorithms during nominal operation and in abnormal conditions. Further it is intended to use SatLab for validation of various algorithms for fault detection, accommodation and supervisory control. Different mission objectives...... can be implemented in the laboratory, e.g. three-axis attitude control, slew manoeuvres, spins stabilization using magnetic actuation and/or reaction wheels. The spacecraft attitude can be determined applying magnetometer measurements...

  3. The Microscale Laboratory.

    Science.gov (United States)

    Zipp, Arden P., Ed.

    1990-01-01

    Described are two microscale chemistry laboratory experiments including "Microscale Syntheses of Heterocyclic Compounds," and "Microscale Acid-Base Extraction--A Colorful Introduction." Materials, procedures and probable results are discussed. (CW)

  4. Physics Laboratory in UEC

    Science.gov (United States)

    Takada, Tohru; Nakamura, Jin; Suzuki, Masaru

    All the first-year students in the University of Electro-Communications (UEC) take "Basic Physics I", "Basic Physics II" and "Physics Laboratory" as required subjects; Basic Physics I and Basic Physics II are calculus-based physics of mechanics, wave and oscillation, thermal physics and electromagnetics. Physics Laboratory is designed mainly aiming at learning the skill of basic experimental technique and technical writing. Although 95% students have taken physics in the senior high school, they poorly understand it by connecting with experience, and it is difficult to learn Physics Laboratory in the university. For this reason, we introduced two ICT (Information and Communication Technology) systems of Physics Laboratory to support students'learning and staff's teaching. By using quantitative data obtained from the ICT systems, we can easily check understanding of physics contents in students, and can improve physics education.

  5. GSPEL - Calorimeter Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Testing performance claims on heat transfer components The Calorimeter Lab, located in the Ground Systems Power and Energy Lab (GSPEL), is one of the largest in the...

  6. Key Management Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Provides a secure environment to research and develop advanced electronic key management and networked key distribution technologies for the Navy and DoD....

  7. Understanding Laboratory Tests

    Science.gov (United States)

    ... and Drug Administration (FDA) regulates the development and marketing of all laboratory tests that use test kits ... at the National Institutes of Health FOLLOW US Facebook Twitter Instagram YouTube Google+ LinkedIn GovDelivery RSS CONTACT ...

  8. Structural Static Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Structural testing is performed to verify the structural integrity of space flight and ground test hardware. Testing is also performed to verify the finite element...

  9. Inorganic Coatings Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The inorganic Coatings Lab provides expertise to Navy and Joint Service platforms acquisition IPTs to aid in materials and processing choices which balance up-front...

  10. Alloy Fabrication Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — At NETL’s Alloy Fabrication Facility in Albany, OR, researchers conduct DOE research projects to produce new alloys suited to a variety of applications, from gas...

  11. Immersive Simulation Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Develops and tests novel user interfaces for 3D virtual simulators and first-person shooter games that make user interaction more like natural interaction...

  12. GSPEL - Fuel Cell Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Fuel Cell Lab (FCL) Provides testing for technology readiness of fuel cell systems The FCL investigates, tests and verifies the performance of fuel-cell systems...

  13. European Molecular Biology Laboratory

    CERN Multimedia

    1973-01-01

    On 10 May an Agreement was signed at CERN setting up a new European Laboratory. It will be concerned with research in molecularbiology and will be located at Heidelberg in the Federal Republic of Germany.

  14. Satellite Control Laboratory

    DEFF Research Database (Denmark)

    Wisniewski, Rafal; Bak, Thomas

    2001-01-01

    The Satellite Laboratory at the Department of Control Engineering of Aalborg University (SatLab) is a dynamic motion facility designed for analysis and test of micro spacecraft. A unique feature of the laboratory is that it provides a completely gravity-free environment. A test spacecraft...... of the laboratory is to conduct dynamic tests of the control and attitude determination algorithms during nominal operation and in abnormal conditions. Further it is intended to use SatLab for validation of various algorithms for fault detection, accommodation and supervisory control. Different mission objectives...... can be implemented in the laboratory, e.g. three-axis attitude control, slew manoeuvres, spins stabilization using magnetic actuation and/or reaction wheels. The spacecraft attitude can be determined applying magnetometer measurements....

  15. RAS Laboratory Groups

    Science.gov (United States)

    The RAS Initiative uses multiple technologies to attack RAS-driven cancers. The resources of the Frederick National Lab allocated to the RAS Hub are organized into seven laboratory groups, each contributing to the collaborative effort.

  16. Sandia National Laboratories

    Data.gov (United States)

    Federal Laboratory Consortium — For more than 60 years, Sandia has delivered essential science and technology to resolve the nation[HTML_REMOVED]s most challenging security issues. Sandia National...

  17. Laboratory animal allergy.

    OpenAIRE

    Hollander, A

    1997-01-01

    The main objective of the study presented in this thesis was to estimate the prevalence rate of laboratory animal allergy and to determine its association with risk factors, like allergen exposure level, atopy, gender and other host factors. A cross-sectional survey was undertaken among 540 workers at 8 laboratory animal facilities. All participants completed a questionnaire and underwent skin prick testing with common and occupational allergens. Total and specific IgE measures were obtained....

  18. Lighting – laboratory practice

    Directory of Open Access Journals (Sweden)

    Борис Васильевич Дзюндзюк

    2014-10-01

    Full Text Available In this article discussed one of the possible variants of the building study bench for laboratory work and practical lessons on the basic parameters of the study of artificial and natural lighting in the labour protection in accordance with the DBN V.2.5-28-2006. The model is on the latest LED components, which has high reliability, maintainability and eliminates the disadvantages of the existing laboratory stands.

  19. Singapore - US Strategic Dialogue on Biosecurity

    OpenAIRE

    Gronvall, Gigi Kwik; Ravi, Sanjana; Cicero, Anita; Inglesby, Tom

    2014-01-01

    Singapore is a critical security partner to the US in Southeast Asia. The US and Singapore share long-standing military relations, with American forces making use of Singapore’s Naval Base facilities, contributing to peace and stabilizing efforts throughout the region, offering humanitarian assistance, and acting as a deterrent to potential security threats.1 US-Singaporean security cooperation also extends to bilateral exercises, joint military training activities, and cargo screening effort...

  20. Understanding trade pathways to target biosecurity surveillance

    Directory of Open Access Journals (Sweden)

    Manuel Colunga-Garcia

    2013-09-01

    Full Text Available Increasing trends in global trade make it extremely difficult to prevent the entry of all potential invasive species (IS. Establishing early detection strategies thus becomes an important part of the continuum used to reduce the introduction of invasive species. One part necessary to ensure the success of these strategies is the determination of priority survey areas based on invasion pressure. We used a pathway-centred conceptual model of pest invasion to address these questions: what role does global trade play in invasion pressure of plant ecosystems and how could an understanding of this role be used to enhance early detection strategies? We concluded that the relative level of invasion pressure for destination ecosystems can be influenced by the intensity of pathway usage (import volume and frequency, the number and type of pathways with a similar destination, and the number of different ecological regions that serve as the source for imports to the same destination. As these factors increase, pressure typically intensifies because of increasing a propagule pressure, b likelihood of transporting pests with higher intrinsic invasion potential, and c likelihood of transporting pests into ecosystems with higher invasibility. We used maritime containerized imports of live plants into the contiguous U.S. as a case study to illustrate the practical implications of the model to determine hotspot areas of relative invasion pressure for agricultural and forest ecosystems (two ecosystems with high potential invasibility. Our results illustrated the importance of how a pathway-centred model could be used to highlight potential target areas for early detection strategies for IS. Many of the hotspots in agricultural and forest ecosystems were within major U.S. metropolitan areas. Invasion ecologists can utilize pathway-centred conceptual models to a better understand the role of human-mediated pathways in pest establishment, b enhance current methodologies for IS risk analysis, and c develop strategies for IS early detection-rapid response programs.

  1. Biosecurity Techbase FY07 Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Gardner, S N; Williams, P L

    2007-10-22

    This tech base award has close links with the Viral Identification Characterization Initiative (VICI) ER LDRD. The tech base extends developed code to enable a capability for biodefense, biosurveillance, and clinical diagnostics. The code enables the design of signatures to detect and discover viruses, without relying on prior assumptions as to the species of virus present. This approach for primer and signature design contrasts with more traditional PCR approaches, in which a major weakness is the unlikelihood of viral discovery or detection of unanticipated species. There were three crucial areas of the project that were not research and development, so could not be funded under the ER LDRD, but were a reduction to practice of the existing VICI algorithm that were necessary for the success of overall computational project goals. These areas, funded by the 2007 Tech Base award, were: (1) improvement of the code developed under the VICI LDRD by incorporating T{sub m} and free energy predictions using Unafold; (2) porting of code developed on the kpath Sun Solaris cluster to the Yana and Zeus LC machines; and (3) application of that code to perform large numbers of simulations to determine parameter effects.

  2. Emerging Technologies: Biosecurity and Consequence Management Implications

    Science.gov (United States)

    Perkins, Dana; Nordmann, Brian

    The natural outbreaks of disease and pandemics are transnational threats that create international challenges when detection and containment are not timely due to scarce human and material resources. Whether the cause of those outbreaks is natural or intentional in origin, the main goal of consequence management operations is to save lives. The consequence management process is a continuum of inter-connected phases such as planning, preparation, response, and recovery. The rapid advances of life sciences and the emergence of dual-use technologies such as synthetic biology and nanotechnology pose additional challenges in terms of planning for the unknown potential threats whether they may be synthetic microorganisms with unpredictable dissemination patterns or nanoscale-manipulated biological agents evading current detection capabilities. The US National Strategy for Countering Biological Threats is emphasizing prevention while continuing to support the national preparedness goals and response/recovery capabilities. The recent policies, guidelines, and recommendations on overhauling the biological risk management in the United States are a proactive stance to a rapidly changing global environment. They include optimization of the current oversight frameworks and active engagement of the industry and academia in order to reduce the risk that individuals with ill intent may exploit the commercial application of nucleic acid synthesis technology to access genetic material derived from or by encoding Biological Select Agents or Toxins. We are also actively seeking to increase our knowledge of health effects of various types of nanomaterials, and how to assess, control, and prevent harmful exposure, taking into consideration the numerous gaps that currently exist with regard to the distinct behavior of nanoparticles compared to the same chemical or material at "macro-scale". Fundamentally, a biological incident, whether it is of natural, accidental, or deliberate origin, constitutes a public health problem and the United States is engaged with the international community to enhance our collective capability to address emerging health security threats.

  3. Biosecurity and ecology: beyond the nativist debate

    OpenAIRE

    Fall, Juliet Jane

    2014-01-01

    In this chapter, and moving on from the example of the globally mobile and invasive Knapweed, I explore how the idea of nativism structures both conservation policy and the publics' sanctioned relationships with nature. This is a highly contested terrain, receiving critique and debate from a wide variety of natural scientists, social scientists, activists and stakeholders. It continues to be a difficult dialogue, with tempers flaring on all sides. Debates about the definition of what is “natu...

  4. Biossegurança e desastres: conceitos, prevenção, saúde pública e manejo de cadáveres Biosecurity and disaster: concepts, prevention, public health and management of corpses

    Directory of Open Access Journals (Sweden)

    Telma Abdalla de Oliveira Cardoso

    2012-01-01

    Full Text Available O artigo discute a complexidade dos desastres, realçando situações de risco e a essencialidade do suporte da Biossegurança, uma vez que, em episódios com vítimas fatais, os procedimentos formulados por este campo devem ser adotados no manejo de cadáveres, sobretudo quando da ocorrência de soterramento com busca de corpos. Contextualiza a magnitude dos desastres caracterizados pelas chuvas e suas consequências (deslizamentos, soterramento, enfatizando o fenômeno do aquecimento global e as mudanças climáticas e seus impactos sobre as comunidades, em especial as mais pobres, valorizando a análise do conceito de vulnerabilidade a partir do cenário da urbanização, da degradação do meio ambiente causada pelo manejo inadequado dos recursos naturais, da contaminação ambiental, das políticas públicas ineficientes, sublinhando o baixo investimento em infraestrutura. Sublinha o conceito de desastre como fenômeno imprevisível, súbito e violento, que causa grande número de mortos e destruição. Enfatiza as problemáticas sociais, sanitárias, jurídicas e operacionais quando do registro de um número elevado mortes ocorridas ao mesmo tempo ou em curto espaço de tempo. Traz para a análise a contribuição da Biossegurança como orientadora dos planos de emergência voltados para os desastres, realçando o risco biológico e as medidas necessárias para o manejo de cadáveres.The paper discusses the complexity of disasters, enhancing risk situations and the importance of support from Biosecurity, as in episodes with fatalities, procedures formulated by this field should be adopted in the handling of corpses, particularly when occurring with search of buried bodies. It contextualizes the magnitude of the disaster characterized by rain and its aftermath (landslides, burying, emphasizing the phenomenon of global warming and climate change and its impacts on communities, especially the poorest, valuing the concept analysis of

  5. San Juan District Laboratory (SJN)

    Data.gov (United States)

    Federal Laboratory Consortium — Program Capabilities SJN-DO Pharmaceutical Laboratory is an A2LA/ISO/IEC 17025 accredited National Servicing Laboratory specialized in Drug Analysis, is a member of...

  6. Physics laboratory 2

    International Nuclear Information System (INIS)

    The report covers the research activities of the Physics laboratory of H.C. Oersted Institute, University of Copenhagen in the period January 1, 1976 - January 1, 1979. It gives also an idea about the teaching carried out by yhe laboratory. The research - broadly speaking - deals mainly with the interaction of particles (ions, electrons and neutrons) and electromagnetic radiation (X-rays) with matter. Use is made in studies of: atomic physics, radiation effects, surface physics, the electronic and crystallographic structure of matter and some biological problems. The research is carried out partly in the laboratory itself and partly at and in collaboration with other institutes in this country (H.C. Oersted Institute, Chemical Laboratories, Denmark's Technical University, Aarhus University, Institute of Physics and Risoe National Laboratory) and abroad (Federal Republic of Germany, France, India, Sweden, U.K., U.S.A. and U.S.S.R.). All these institutes are listed in the abstract titles. Bibliography comprehends 94 publications. A substantial part of the research is supported by the Danish Natural Sciences Research Council. (author)

  7. [Laboratory medicine in Taiwan].

    Science.gov (United States)

    Chen, J S

    1998-07-01

    Laboratory medicine and hospital central laboratory system were adopted in Taiwan after World War II. In medical schools, laboratory medicine or clinical pathology teaching is allocated to junior students. Three years of clinical pathology or four years of anatomical pathology training is required for pathology resident. Recent trend indicates that both the hospitals and the young doctors favor the five years combined C.P. (two-years) and A.P. (three years) training program. At present, 75 clinical pathologists and 213 anatomical pathologists are qualified. Approximately 70% of them work in medical centers and medical schools. Consequently, the medium and small size hospitals suffer from serious shortage of pathologist. Studies during the part 50 years indicate substantial difference in the improvement of laboratory medicine and central laboratory before and after 1975. Significant improvement in the working space, facility, equipment, staff, quality control and productivity was evident after 1975. The three health care policies contributing to the overall improvement are: 1. hospital accreditation project, 2. medical care network plan, and 3. medical specialist system.

  8. Sandia Laboratories energy programs

    Energy Technology Data Exchange (ETDEWEB)

    Lundergan, C.D.; Mead, P.L.; Gillespie, R.S. (eds.)

    1977-03-01

    As one of the multiprogram laboratories of the Energy Research and Development Administration, Sandia Laboratories applies its resources to a number of nationally important programs. About 75 percent of these resources are applied to research and development for national security programs having to do primarily with nuclear weapons--the principal responsibility of the Laboratories. The remaining 25 percent are applied to energy programs and energy-related activities, particularly those requiring resources that are also used in nuclear weapon and other national security programs. Examples of such energy programs and activities are research into nuclear fusion, protection of nuclear materials from theft or diversion, and the disposal of radioactive waste. A number of technologies and disciplines developed for the weapon program are immediately applicable for the development of various energy sources. Instruments developed to detect, measure, and record the detonation of nuclear devices underground, now being used to support the development of in-situ processing of coal and oil shale, are examples. The purpose of this report is to provide an overview of these and other energy programs being conducted by these laboratories in the development of economical and environmentally acceptable alternative energy sources. Energy programs are undertaken when they require capabilities used at the Laboratories for the weapon program, and when they have no adverse effect upon that primary mission. The parallel operation of weapon and energy activities allows optimum use of facilities and other resources.

  9. Laboratory medicine education in Lithuania

    OpenAIRE

    Kucinskiene, Zita Ausrele; Bartlingas, Jonas

    2011-01-01

    In Lithuania there are two types of specialists working in medical laboratories and having a university degree: laboratory medicine physicians and medical biologists. Both types of specialists are officially being recognized and regulated by the Ministry of Health of Lithuania. Laboratory medicine physicians become specialists in laboratory medicine after an accredited 4-year multidisciplinary residency study program in Laboratory Medicine. The residency program curriculum for laboratory m...

  10. 3D Printing in the Laboratory: Maximize Time and Funds with Customized and Open-Source Labware.

    Science.gov (United States)

    Coakley, Meghan; Hurt, Darrell E

    2016-08-01

    3D printing, also known as additive manufacturing, is the computer-guided process of fabricating physical objects by depositing successive layers of material. It has transformed manufacturing across virtually every industry, bringing about incredible advances in research and medicine. The rapidly growing consumer market now includes convenient and affordable "desktop" 3D printers. These are being used in the laboratory to create custom 3D-printed equipment, and a growing community of designers are contributing open-source, cost-effective innovations that can be used by both professionals and enthusiasts. User stories from investigators at the National Institutes of Health and the biomedical research community demonstrate the power of 3D printing to save valuable time and funding. While adoption of 3D printing has been slow in the biosciences to date, the potential is vast. The market predicts that within several years, 3D printers could be commonplace within the home; with so many practical uses for 3D printing, we anticipate that the technology will also play an increasingly important role in the laboratory. PMID:27197798

  11. 3D Printing in the Laboratory: Maximize Time and Funds with Customized and Open-Source Labware.

    Science.gov (United States)

    Coakley, Meghan; Hurt, Darrell E

    2016-08-01

    3D printing, also known as additive manufacturing, is the computer-guided process of fabricating physical objects by depositing successive layers of material. It has transformed manufacturing across virtually every industry, bringing about incredible advances in research and medicine. The rapidly growing consumer market now includes convenient and affordable "desktop" 3D printers. These are being used in the laboratory to create custom 3D-printed equipment, and a growing community of designers are contributing open-source, cost-effective innovations that can be used by both professionals and enthusiasts. User stories from investigators at the National Institutes of Health and the biomedical research community demonstrate the power of 3D printing to save valuable time and funding. While adoption of 3D printing has been slow in the biosciences to date, the potential is vast. The market predicts that within several years, 3D printers could be commonplace within the home; with so many practical uses for 3D printing, we anticipate that the technology will also play an increasingly important role in the laboratory.

  12. A biossegurança e segurança do paciente na visão de acadêmicos de enfermagem La bioseguridad y seguridad del paciente bajo la visión de académicos de enfermería Nursing students' point of view on biosecurity and patient safety

    Directory of Open Access Journals (Sweden)

    Telma Elisa Cararro

    2012-09-01

    area of patient safety and its relationship with the teaching of biosecurity. Exploratory qualitative study conducted at the Universidade Federal de Santa Catarina (Federal University of Santa Catarina, with 17 students in the third phase of the Undergraduate Nursing Program. Three categories emerged after an exhaustive reading of the responses: caring for self and others; biosecurity and care for the environment; biosecurity: health education and continuing education in health services. The following issues were identified: students' concern about risk prevention; care and self care as prerogatives for patient's safety; and education as a proposal for the minimization of risks. The study of biosecurity is considered important in undergraduate studies, minimizing losses and mistakes in the undergraduate students' conduct.

  13. Space Food Systems Laboratory

    Science.gov (United States)

    Perchonok, Michele; Russo, Dane M. (Technical Monitor)

    2001-01-01

    The Space Food Systems Laboratory (SFSL) is a multipurpose laboratory responsible for space food and package research and development. It is located on-site at Johnson Space Center in Building 17. The facility supports the development of flight food, menus, packaging and food related hardware for Shuttle, International Space Station, and Advanced Life Support food systems. All foods used to support NASA ground tests and/or missions must meet the highest standards before they are 'accepted' for use on actual space flights. The foods are evaluated for nutritional content, sensory acceptability, safety, storage and shelf life, and suitability for use in micro-gravity. The food packaging is also tested to determine its functionality and suitability for use in space. Food Scientist, Registered Dieticians, Packaging Engineers, Food Systems Engineers, and Technicians staff the Space Food Systems Laboratory.

  14. Laboratory Accreditation in Argentina.

    Science.gov (United States)

    Acuña, María Amelia; Collino, Cesar; Chiabrando, Gustavo A

    2015-11-01

    Laboratory accreditation is an essential element in the healthcare system since it contributes substantially to decision-making, in the prevention, diagnosis, treatment and follow-up of the health status of the patients, as well as in the organization and management of public healthcare. Therefore, the clinical biochemistry professional works continuously to provide reliable results and contributes to the optimization of operational logistics and integration of a laboratory into the health system. ISO 15189 accreditation, ensures compliance of the laboratory to minimize instances of error through the planning, prevention, implementation, evaluation and improvement of its procedures, which provides skill areas that involve both training undergraduate and graduate professionals in clinical biochemistry. PMID:27683497

  15. INFORMATION SYSTEMS TECHNOLOGY LABORATORY (ISTL)

    Data.gov (United States)

    Federal Laboratory Consortium — Background: The Naval Automated Information Laboratory (NAIL), consisting of Navy legacy and transitional systems, was established to emulate a typical command for...

  16. San Francisco District Laboratory (SAN)

    Data.gov (United States)

    Federal Laboratory Consortium — Program Capabilities Food Analysis SAN-DO Laboratory has an expert in elemental analysis who frequently performs field inspections of materials. A recently acquired...

  17. Robotics and Autonomous Systems Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Provides an environment for developing and evaluating intelligent software for both actual and simulated autonomous vehicles. Laboratory computers provide...

  18. Analytical laboratory quality audits

    Energy Technology Data Exchange (ETDEWEB)

    Kelley, William D.

    2001-06-11

    Analytical Laboratory Quality Audits are designed to improve laboratory performance. The success of the audit, as for many activities, is based on adequate preparation, precise performance, well documented and insightful reporting, and productive follow-up. Adequate preparation starts with definition of the purpose, scope, and authority for the audit and the primary standards against which the laboratory quality program will be tested. The scope and technical processes involved lead to determining the needed audit team resources. Contact is made with the auditee and a formal audit plan is developed, approved and sent to the auditee laboratory management. Review of the auditee's quality manual, key procedures and historical information during preparation leads to better checklist development and more efficient and effective use of the limited time for data gathering during the audit itself. The audit begins with the opening meeting that sets the stage for the interactions between the audit team and the laboratory staff. Arrangements are worked out for the necessary interviews and examination of processes and records. The information developed during the audit is recorded on the checklists. Laboratory management is kept informed of issues during the audit so there are no surprises at the closing meeting. The audit report documents whether the management control systems are effective. In addition to findings of nonconformance, positive reinforcement of exemplary practices provides balance and fairness. Audit closure begins with receipt and evaluation of proposed corrective actions from the nonconformances identified in the audit report. After corrective actions are accepted, their implementation is verified. Upon closure of the corrective actions, the audit is officially closed.

  19. Underground laboratories in Asia

    International Nuclear Information System (INIS)

    Deep underground laboratories in Asia have been making huge progress recently because underground sites provide unique opportunities to explore the rare-event phenomena for the study of dark matter searches, neutrino physics and nuclear astrophysics as well as the multi-disciplinary researches based on the low radioactive environments. The status and perspectives of Kamioda underground observatories in Japan, the existing Y2L and the planned CUP in Korea, India-based Neutrino Observatory (INO) in India and China JinPing Underground Laboratory (CJPL) in China will be surveyed

  20. Underground laboratories in Asia

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Shin Ted, E-mail: linst@mails.phys.sinica.edu.tw [College of Physical Science and Technology, Sichuan University, Chengdu 610064 China (China); Yue, Qian, E-mail: yueq@mail.tsinghua.edu.cn [Key Laboratory of Particle and Radiation Imaging (Ministry of Education) and Department of Engineering Physics, Tsinghua University, Beijing 100084 China (China)

    2015-08-17

    Deep underground laboratories in Asia have been making huge progress recently because underground sites provide unique opportunities to explore the rare-event phenomena for the study of dark matter searches, neutrino physics and nuclear astrophysics as well as the multi-disciplinary researches based on the low radioactive environments. The status and perspectives of Kamioda underground observatories in Japan, the existing Y2L and the planned CUP in Korea, India-based Neutrino Observatory (INO) in India and China JinPing Underground Laboratory (CJPL) in China will be surveyed.

  1. Laboratory analysis of stardust.

    Science.gov (United States)

    Zinner, Ernst

    2013-02-01

    Tiny dust grains extracted from primitive meteorites are identified to have originated in the atmospheres of stars on the basis of their anomalous isotopic compositions. Although isotopic analysis with the ion microprobe plays a major role in the laboratory analysis of these stardust grains, many other microanalytical techniques are applied to extract the maximum amount of information.

  2. Laboratory Density Functionals

    OpenAIRE

    Giraud, B. G.

    2007-01-01

    We compare several definitions of the density of a self-bound system, such as a nucleus, in relation with its center-of-mass zero-point motion. A trivial deconvolution relates the internal density to the density defined in the laboratory frame. This result is useful for the practical definition of density functionals.

  3. Personnel Scheduling in Laboratories

    NARCIS (Netherlands)

    Franses, Philip; Post, Gerhard; Burke, Edmund; De Causmaecker, Patrick

    2003-01-01

    We describe an assignment problem particular to the personnel scheduling of organisations such as laboratories. Here we have to assign tasks to employees. We focus on the situation where this assignment problem reduces to constructing maximal matchings in a set of interrelated bipartite graphs. We d

  4. Laboratories: Integrating Services

    Centers for Disease Control (CDC) Podcasts

    2011-04-04

    This podcast highlights the importance of integrating laboratory services to maximize service delivery to patients.  Created: 4/4/2011 by National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP).   Date Released: 4/7/2011.

  5. Revitalizing chemistry laboratory instruction

    Science.gov (United States)

    McBride, Phil Blake

    This dissertation involves research in three major domains of chemical education as partial fulfillment of the requirements for the Ph.D. program in chemistry at Miami University with a major emphasis on chemical education, and concurrent study in organic chemistry. Unit I, Development and Assessment of a Column Chromatography Laboratory Activity, addresses the domain of Instructional Materials Development and Testing. This unit outlines the process of developing a publishable laboratory activity, testing and revising that activity, and subsequently sharing that activity with the chemical education community. A laboratory activity focusing on the separation of methylene blue and sodium fluorescein was developed to demonstrate the effects of both the stationary and mobile phase in conducting a separation. Unit II, Bringing Industry to the Laboratory, addresses the domain of Curriculum Development and Testing. This unit outlines the development of the Chemistry of Copper Mining module, which is intended for use in high school or undergraduate college chemistry. The module uses the learning cycle approach to present the chemistry of the industrial processes of mining copper to the students. The module includes thirteen investigations (three of which are web-based and ten which are laboratory experiments) and an accompanying interactive CD-ROM, which provides an explanation of the chemistry used in copper mining with a virtual tour of an operational copper mine. Unit III, An Alternative Method of Teaching Chemistry. Integrating Lecture and the Laboratory, is a project that addresses the domain of Research in Student Learning. Fundamental Chemistry was taught at Eastern Arizona College as an integrated lecture/laboratory course that met in two-hour blocks on Monday, Wednesday, and Friday. The students taking this integrated course were compared with students taking the traditional 1-hour lectures held on Monday, Wednesday, and Friday, with accompanying 3-hour lab on

  6. International atomic laboratory

    International Nuclear Information System (INIS)

    Some thirty kilometers to the south-east of Vienna, in the village of Seibersdorf, the International Atomic Energy Agency will have its functional laboratory, the first atomic laboratory to be built by peaceful world-wide co-operation. The building is expected to be completed around the middle of 1960 and the scientific installations will start immediately thereafter. The staff (14 Professional and 24 of the General Service category) for the laboratory are also expected to be engaged at that time and it should be possible to start operating the laboratory in the last quarter of 1960. It is estimated that the construction work will cost about US $400 000 and the total equipment will be worth between $200 000 and $300 000. The United States Government is donating $600 000 for this purpose. The operating costs during 1961, the first full year of operation, will be a little over $240 000. The scope of the laboratory should be limited to certain broad functions. The maximum functions envisaged were: (a) standardization of isotopes and preparation of radioactive standards; (b) calibration and adaptation of measuring equipment; (c) quality control of special materials for nuclear technology; (d) measurements and analysis in connexion with the Agency's safeguards and health and safety programme; and (e) services for Member States which can be undertaken with the facilities needed for the former activities. The idea behind this recommendation will be clear if it is remembered that the research functions of the Agency are governed mostly by its other activities, by its Statutory obligation to encourage and assist peaceful atomic energy work in Member States and establish standards for health and safety and for safeguards against military use

  7. Laboratory Waste Management. A Guidebook.

    Science.gov (United States)

    American Chemical Society, Washington, DC.

    A primary goal of the American Chemical Society Task Force on Laboratory Waste Management is to provide laboratories with the information necessary to develop effective strategies and training programs for managing laboratory wastes. This book is intended to present a fresh look at waste management from the laboratory perspective, considering both…

  8. Smart Grid Integration Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Troxell, Wade [Colorado State Univ., Fort Collins, CO (United States)

    2011-12-22

    The initial federal funding for the Colorado State University Smart Grid Integration Laboratory is through a Congressionally Directed Project (CDP), DE-OE0000070 Smart Grid Integration Laboratory. The original program requested in three one-year increments for staff acquisition, curriculum development, and instrumentation all which will benefit the Laboratory. This report focuses on the initial phase of staff acquisition which was directed and administered by DOE NETL/ West Virginia under Project Officer Tom George. Using this CDP funding, we have developed the leadership and intellectual capacity for the SGIC. This was accomplished by investing (hiring) a core team of Smart Grid Systems engineering faculty focused on education, research, and innovation of a secure and smart grid infrastructure. The Smart Grid Integration Laboratory will be housed with the separately funded Integrid Laboratory as part of CSU's overall Smart Grid Integration Center (SGIC). The period of performance of this grant was 10/1/2009 to 9/30/2011 which included one no cost extension due to time delays in faculty hiring. The Smart Grid Integration Laboratory's focus is to build foundations to help graduate and undergraduates acquire systems engineering knowledge; conduct innovative research; and team externally with grid smart organizations. Using the results of the separately funded Smart Grid Workforce Education Workshop (May 2009) sponsored by the City of Fort Collins, Northern Colorado Clean Energy Cluster, Colorado State University Continuing Education, Spirae, and Siemens has been used to guide the hiring of faculty, program curriculum and education plan. This project develops faculty leaders with the intellectual capacity to inspire its students to become leaders that substantially contribute to the development and maintenance of Smart Grid infrastructure through topics such as: (1) Distributed energy systems modeling and control; (2) Energy and power conversion; (3

  9. Students' laboratory work performance assessment

    OpenAIRE

    Achumba, Ifeyinwa; Azzi, Djamel; Williams, Roy

    2008-01-01

    Laboratory activities are very important in engineering education. Performance assessment of students’ laboratory work is time consuming and an ongoing challenge for teachers. Laboratory work performance assessment is traditionally done by the teacher grading students’ written report of the laboratory activity, despite the fact that the report is often 'doctored'. Assessment of laboratory work based solely on students’ reports has been criticized as failing to address espoused aims. The asses...

  10. Procedures of Exercise Physiology Laboratories

    Science.gov (United States)

    Bishop, Phillip A.; Fortney, Suzanne; Greenisen, Michael; Siconolfi, Steven F.; Bamman, Marcas M.; Moore, Alan D., Jr.; Squires, William

    1998-01-01

    This manual describes the laboratory methods used to collect flight crew physiological performance data at the Johnson Space Center. The Exercise Countermeasures Project Laboratory is a standard physiology laboratory; only the application to the study of human physiological adaptations to spaceflight is unique. In the absence of any other recently published laboratory manual, this manual should be a useful document staffs and students of other laboratories.

  11. Health Physics Laboratory - Overview

    International Nuclear Information System (INIS)

    Full text: The activities of the Health Physics Laboratory at the Institute of Nuclear Physics (IFJ) in Cracow are principally research in the general area of radiation physics, dosimetry and radiation protection of the employees of the Institute. Theoretical research concerns modelling of radiation effects in radiation detectors and studies of concepts in radiation protection. Experimental research, in the general area of solid state dosimetry, is primarily concerned with thermoluminescence (TL) dosimetry, and more specifically: development of LiF:Mg, Ti, CaF2:Tm and CVD diamond detectors for medical applications in conventional and hadron radiotherapy and of LiF:Mg, Cu, P and LiF:Mg, Cu, Si, Na for low-level natural external ionising radiation. Environmental radiation measurements (cosmic-rays on aircraft and radon in dwellings and soil) are also performed using track CR-39 and TLD detectors. The Laboratory provides expert advice on radiation protection regulations at national and international levels. Routine work of the Health Physics Laboratory involves design and maintenance of an in-house developed TL-based personnel dosimetry system for over 200 radiation workers at the INP, supervision of radiation safety on IFJ premises, and advising other INP laboratories on all matters pertaining to radiation safety. We provide personal and environmental TLD dosimetry services for several customers outside the IFJ, mainly in hospitals and nuclear research institutes in Poland. We also calibrate radiation protection instruments (400 per year) for customers in the southern region of Poland. The year 2001 was another eventful year for the Health Physics Laboratory. M. Waligorski has received his Professor of Physics state nomination from A. Kwasniewski, the President of Poland. P. Bilski and M. Budzanowski were granted their Ph.D. degrees by the Scientific Council of the Institute of Nuclear Physics. We continued several national and international research projects. Dr

  12. Rutherford Appleton Laboratory

    International Nuclear Information System (INIS)

    Rutherford Appleton Laboratory (RAL), described in this document, supports a wide variety of projects. Each year more than 1000 scientists and engineers visit RAL to use its world-class laser and neutron-scattering facilities. RAL staff design and build instruments which circle the Earth in satellites, increasing our understanding of ozone depletion and global warming, of the life cycles of stars and galaxies and, indeed, of the origin of the Universe itself. They work with their academic colleagues at international laboratories such as European Organization for Nuclear Research (CERN), Geneva, where massive underground machines probe the microstructure of the atomic nucleus. Vastly complex calculations are carried out on the design of anti-cancer drugs, for example, using supercomputers at RAL. (author)

  13. Process innovation laboratory

    DEFF Research Database (Denmark)

    Møller, Charles

    2007-01-01

    Most organizations today are required not only to operate effective business processes but also to allow for changing business conditions at an increasing rate. Today nearly every business relies on their enterprise information systems (EIS) for process integration and future generations of EIS...... will increasingly be driven by business process models. Consequently business process modelling and improvement is becoming a serious challenge. The aim of this paper is to establish a conceptual framework for business process innovation (BPI) in the supply chain based on advanced EIS. The challenge is thus...... to create a new methodology for developing and exploring process models and applications. The paper outlines the process innovation laboratory as a new approach to BPI. The process innovation laboratory is a comprehensive framework and a collaborative workspace for experimenting with process models...

  14. High Resolution Laboratory Spectroscopy

    CERN Document Server

    Brünken, Sandra

    2016-01-01

    In this short review we will highlight some of the recent advancements in the field of high-resolution laboratory spectroscopy that meet the needs dictated by the advent of highly sensitive and broadband telescopes like ALMA and SOFIA. Among these is the development of broadband techniques for the study of complex organic molecules, like fast scanning conventional absorption spectroscopy based on multiplier chains, chirped pulse instrumentation, or the use of synchrotron facilities. Of similar importance is the extension of the accessible frequency range to THz frequencies, where many light hydrides have their ground state rotational transitions. Another key experimental challenge is the production of sufficiently high number densities of refractory and transient species in the laboratory, where discharges have proven to be efficient sources that can also be coupled to molecular jets. For ionic molecular species sensitive action spectroscopic schemes have recently been developed to overcome some of the limita...

  15. Health Physic Laboratory - overview

    Energy Technology Data Exchange (ETDEWEB)

    Waligorski, M.P.R. [Institute of Nuclear Physics, Cracow (Poland)

    1994-12-31

    The activities of the Health Physics Laboratory at the Institute of Nuclear Physics in Krakow are principally research in the general area of radiation physics, and radiation protection of the employees of the Institute of Nuclear Physics. Theoretical research concerns radiation detectors, radiation protection (modelling of radiation effects in biological and physical systems) and studies of concepts in radiation protection. Experimental research concerns solid state dosimetry mainly thermoluminescence (TL) dosimetry (present thrust: development of thin TL detectors for beta-ray and mixed neutron field dosimetry, development of ultra-sensitive LiF; Mg,Cu,P phosphors) and environmental radiation measurements (radon in dwellings, low-level natural radiation. The Laboratory provides expert advice on radiation protection regulations at national and international levels).

  16. Hanford cultural resources laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Wright, M.K.

    1995-06-01

    This section of the 1994 Hanford Site Environmental Report describes activities of the Hanford Cultural Resources Laboratory (HCRL) which was established by the Richland Operations Office in 1987 as part of PNL.The HCRL provides support for the management of the archaeological, historical, and traditional cultural resources of the site in a manner consistent with the National Historic Preservation Act, the Native American Graves Protection and Repatriation Act, and the American Indian Religious Freedom Act.

  17. Laboratory Evaluation of Anemia

    OpenAIRE

    Wallerstein, Ralph O.

    1987-01-01

    The laboratory evaluation of anemia begins with a complete blood count and reticulocyte count. The anemia is then categorized as microcytic, macrocytic or normocytic, with or without reticulocytosis. Examination of the peripheral smear and a small number of specific tests confirm the diagnosis. The serum iron level, total iron-binding capacity, serum ferritin level and hemoglobin electrophoresis generally separate the microcytic anemias. The erythrocyte size-distribution width may be particul...

  18. Princeton Plasma Physics Laboratory:

    International Nuclear Information System (INIS)

    This paper discusses progress on experiments at the Princeton Plasma Physics Laboratory. The projects and areas discussed are: Principal Parameters Achieved in Experimental Devices, Tokamak Fusion Test Reactor, Princeton Large Torus, Princeton Beta Experiment, S-1 Spheromak, Current-Drive Experiment, X-ray Laser Studies, Theoretical Division, Tokamak Modeling, Spacecraft Glow Experiment, Compact Ignition Tokamak, Engineering Department, Project Planning and Safety Office, Quality Assurance and Reliability, and Administrative Operations

  19. Remote Laboratory in Photovoltaics

    Directory of Open Access Journals (Sweden)

    Cornel Samoila

    2009-08-01

    Full Text Available This paper presents a new concept of studying, understanding and teaching the performance of solar cells. Using NI ELVIS allows the realization of eight laboratory experiments which study all the important parameters of the solar cells. The model used for the equivalent circuit of the solar cell was the “one diode” model. For the realization of control, data acquisition and processing, a complex program was created, with a friendly interface, using the graphical programming language LabVIEW.

  20. Princeton Plasma Physics Laboratory:

    Energy Technology Data Exchange (ETDEWEB)

    Phillips, C.A. (ed.)

    1986-01-01

    This paper discusses progress on experiments at the Princeton Plasma Physics Laboratory. The projects and areas discussed are: Principal Parameters Achieved in Experimental Devices, Tokamak Fusion Test Reactor, Princeton Large Torus, Princeton Beta Experiment, S-1 Spheromak, Current-Drive Experiment, X-ray Laser Studies, Theoretical Division, Tokamak Modeling, Spacecraft Glow Experiment, Compact Ignition Tokamak, Engineering Department, Project Planning and Safety Office, Quality Assurance and Reliability, and Administrative Operations.

  1. Cleanroom laboratory challenge overcome.

    Science.gov (United States)

    Quinn, Ronan

    2010-10-01

    Ronan Quinn, managing director of interior construction specialist Ardmac, describes the challenges of building and fitting out a new cleanroom laboratory for blood and bone marrow therapeutic treatment at Our Lady's Children's Hospital Crumlin in Dublin. The "state-of-the-art" facility, which fully complies with the recent EU Directive concerning human tissues and cells, has been well received by the client and end-users alike, but, as he explains, there were many obstacles to overcome during its completion.

  2. Laboratory microfusion capability study

    International Nuclear Information System (INIS)

    The purpose of this study is to elucidate the issues involved in developing a Laboratory Microfusion Capability (LMC) which is the major objective of the Inertial Confinement Fusion (ICF) program within the purview of the Department of Energy's Defense Programs. The study was initiated to support a number of DOE management needs: to provide insight for the evolution of the ICF program; to afford guidance to the ICF laboratories in planning their research and development programs; to inform Congress and others of the details and implications of the LMC; to identify criteria for selection of a concept for the Laboratory Microfusion Facility and to develop a coordinated plan for the realization of an LMC. As originally proposed, the LMC study was divided into two phases. The first phase identifies the purpose and potential utility of the LMC, the regime of its performance parameters, driver independent design issues and requirements, its development goals and requirements, and associated technical, management, staffing, environmental, and other developmental and operational issues. The second phase addresses driver-dependent issues such as specific design, range of performance capabilities, and cost. The study includes four driver options; the neodymium-glass solid state laser, the krypton fluoride excimer gas laser, the light-ion accelerator, and the heavy-ion induction linear accelerator. The results of the Phase II study are described in the present report

  3. Exploration Laboratory Analysis

    Science.gov (United States)

    Krihak, M.; Ronzano, K.; Shaw, T.

    2016-01-01

    The Exploration Laboratory Analysis (ELA) project supports the Exploration Medical Capability (ExMC) risk to minimize or reduce the risk of adverse health outcomes and decrements in performance due to in-flight medical capabilities on human exploration missions. To mitigate this risk, the availability of inflight laboratory analysis instrumentation has been identified as an essential capability for manned exploration missions. Since a single, compact space-ready laboratory analysis capability to perform all exploration clinical measurements is not commercially available, the ELA project objective is to demonstrate the feasibility of emerging operational and analytical capability as a biomedical diagnostics precursor to long duration manned exploration missions. The initial step towards ground and flight demonstrations in fiscal year (FY) 2015 was the down selection of platform technologies for demonstrations in the space environment. The technologies selected included two Small Business Innovation Research (SBIR) performers: DNA Medicine Institutes rHEALTH X and Intelligent Optical Systems later flow assays combined with Holomics smartphone analyzer. The selection of these technologies were based on their compact size, breadth of analytical capability and favorable ability to process fluids in a space environment, among several factors. These two technologies will be advanced to meet ground and flight demonstration success criteria and requirements that will be finalized in FY16. Also, the down selected performers will continue the technology development phase towards meeting prototype deliverables in either late 2016 or 2017.

  4. Laboratory Directed Research and Development Program FY 2008 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    editor, Todd C Hansen

    2009-02-23

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Berkeley Lab's research and the Laboratory Directed Research and Development (LDRD) program support DOE's Strategic Themes that are codified in DOE's 2006 Strategic Plan (DOE/CF-0010), with a primary focus on Scientific Discovery and Innovation. For that strategic theme, the Fiscal Year (FY) 2008 LDRD projects support each one of the three goals through multiple strategies described in the plan. In addition, LDRD efforts support the four goals of Energy Security, the two goals of Environmental Responsibility, and Nuclear Security (unclassified fundamental research that supports stockpile safety and nonproliferation programs). The LDRD program supports Office of Science strategic plans, including the 20-year Scientific Facilities Plan and the Office of Science Strategic Plan. The research also supports the strategic directions periodically under

  5. Laboratory Directed Research and Development Program FY 2008 Annual Report

    International Nuclear Information System (INIS)

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Berkeley Lab's research and the Laboratory Directed Research and Development (LDRD) program support DOE's Strategic Themes that are codified in DOE's 2006 Strategic Plan (DOE/CF-0010), with a primary focus on Scientific Discovery and Innovation. For that strategic theme, the Fiscal Year (FY) 2008 LDRD projects support each one of the three goals through multiple strategies described in the plan. In addition, LDRD efforts support the four goals of Energy Security, the two goals of Environmental Responsibility, and Nuclear Security (unclassified fundamental research that supports stockpile safety and nonproliferation programs). The LDRD program supports Office of Science strategic plans, including the 20-year Scientific Facilities Plan and the Office of Science Strategic Plan. The research also supports the strategic directions periodically under consideration and review by the

  6. Purdue Hydrogen Systems Laboratory

    International Nuclear Information System (INIS)

    The Hydrogen Systems Laboratory in a unique partnership between Purdue University's main campus in West Lafayette and the Calumet campus was established and its capabilities were enhanced towards technology demonstrators. The laboratory engaged in basic research in hydrogen production and storage and initiated engineering systems research with performance goals established as per the USDOE Hydrogen, Fuel Cells, and Infrastructure Technologies Program. In the chemical storage and recycling part of the project, we worked towards maximum recycling yield via novel chemical selection and novel recycling pathways. With the basic potential of a large hydrogen yield from AB, we used it as an example chemical but have also discovered its limitations. Further, we discovered alternate storage chemicals that appear to have advantages over AB. We improved the slurry hydrolysis approach by using advanced slurry/solution mixing techniques. We demonstrated vehicle scale aqueous and non-aqueous slurry reactors to address various engineering issues in on-board chemical hydrogen storage systems. We measured the thermal properties of raw and spent AB. Further, we conducted experiments to determine reaction mechanisms and kinetics of hydrothermolysis in hydride-rich solutions and slurries. We also developed a continuous flow reactor and a laboratory scale fuel cell power generation system. The biological hydrogen production work summarized as Task 4.0 below, included investigating optimal hydrogen production cultures for different substrates, reducing the water content in the substrate, and integrating results from vacuum tube solar collector based pre and post processing tests into an enhanced energy system model. An automated testing device was used to finalize optimal hydrogen production conditions using statistical procedures. A 3 L commercial fermentor (New Brunswick, BioFlo 115) was used to finalize testing of larger samples and to consider issues related to scale up. Efforts

  7. Purdue Hydrogen Systems Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Jay P Gore; Robert Kramer; Timothee L Pourpoint; P. V. Ramachandran; Arvind Varma; Yuan Zheng

    2011-12-28

    The Hydrogen Systems Laboratory in a unique partnership between Purdue University's main campus in West Lafayette and the Calumet campus was established and its capabilities were enhanced towards technology demonstrators. The laboratory engaged in basic research in hydrogen production and storage and initiated engineering systems research with performance goals established as per the USDOE Hydrogen, Fuel Cells, and Infrastructure Technologies Program. In the chemical storage and recycling part of the project, we worked towards maximum recycling yield via novel chemical selection and novel recycling pathways. With the basic potential of a large hydrogen yield from AB, we used it as an example chemical but have also discovered its limitations. Further, we discovered alternate storage chemicals that appear to have advantages over AB. We improved the slurry hydrolysis approach by using advanced slurry/solution mixing techniques. We demonstrated vehicle scale aqueous and non-aqueous slurry reactors to address various engineering issues in on-board chemical hydrogen storage systems. We measured the thermal properties of raw and spent AB. Further, we conducted experiments to determine reaction mechanisms and kinetics of hydrothermolysis in hydride-rich solutions and slurries. We also developed a continuous flow reactor and a laboratory scale fuel cell power generation system. The biological hydrogen production work summarized as Task 4.0 below, included investigating optimal hydrogen production cultures for different substrates, reducing the water content in the substrate, and integrating results from vacuum tube solar collector based pre and post processing tests into an enhanced energy system model. An automated testing device was used to finalize optimal hydrogen production conditions using statistical procedures. A 3 L commercial fermentor (New Brunswick, BioFlo 115) was used to finalize testing of larger samples and to consider issues related to scale up

  8. Laboratory for Extraterrestrial Physics

    Science.gov (United States)

    Vondrak, Richard R. (Technical Monitor)

    2001-01-01

    The NASA Goddard Space Flight Center (GSFC) Laboratory for Extraterrestrial Physics (LEP) performs experimental and theoretical research on the heliosphere, the interstellar medium, and the magnetospheres and upper atmospheres of the planets, including Earth. LEP space scientists investigate the structure and dynamics of the magnetospheres of the planets including Earth. Their research programs encompass the magnetic fields intrinsic to many planetary bodies as well as their charged-particle environments and plasma-wave emissions. The LEP also conducts research into the nature of planetary ionospheres and their coupling to both the upper atmospheres and their magnetospheres. Finally, the LEP carries out a broad-based research program in heliospheric physics covering the origins of the solar wind, its propagation outward through the solar system all the way to its termination where it encounters the local interstellar medium. Special emphasis is placed on the study of solar coronal mass ejections (CME's), shock waves, and the structure and properties of the fast and slow solar wind. LEP planetary scientists study the chemistry and physics of planetary stratospheres and tropospheres and of solar system bodies including meteorites, asteroids, comets, and planets. The LEP conducts a focused program in astronomy, particularly in the infrared and in short as well as very long radio wavelengths. We also perform an extensive program of laboratory research, including spectroscopy and physical chemistry related to astronomical objects. The Laboratory proposes, develops, fabricates, and integrates experiments on Earth-orbiting, planetary, and heliospheric spacecraft to measure the characteristics of planetary atmospheres and magnetic fields, and electromagnetic fields and plasmas in space. We design and develop spectrometric instrumentation for continuum and spectral line observations in the x-ray, gamma-ray, infrared, and radio regimes; these are flown on spacecraft to study

  9. Princeton Plasma Physics Laboratory

    International Nuclear Information System (INIS)

    This report discusses the following topics: principal parameters achieved in experimental devices fiscal year 1990; tokamak fusion test reactor; compact ignition tokamak; Princeton beta experiment- modification; current drive experiment-upgrade; international collaboration; x-ray laser studies; spacecraft glow experiment; plasma processing: deposition and etching of thin films; theoretical studies; tokamak modeling; international thermonuclear experimental reactor; engineering department; project planning and safety office; quality assurance and reliability; technology transfer; administrative operations; PPPL patent invention disclosures for fiscal year 1990; graduate education; plasma physics; graduate education: plasma science and technology; science education program; and Princeton Plasma Physics Laboratory reports fiscal year 1990

  10. [Accreditation of forensic laboratories].

    Science.gov (United States)

    Sołtyszewski, Ireneusz

    2010-01-01

    According to the framework decision of the European Union Council, genetic laboratories which perform tests for the benefit of the law enforcement agencies and the administration of justice are required to obtain a certificate of accreditation testifying to compliance with the PN EN ISO/IEC 17025:2005 standard. The certificate is the official confirmation of the competence to perform research, an acknowledgement of credibility, impartiality and professional independence. It is also the proof of establishment, implementation and maintenance of an appropriate management system. The article presents the legal basis for accreditation, the procedure of obtaining the certificate of accreditation and selected elements of the management system. PMID:21863740

  11. Princeton Plasma Physics Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    1990-01-01

    This report discusses the following topics: principal parameters achieved in experimental devices fiscal year 1990; tokamak fusion test reactor; compact ignition tokamak; Princeton beta experiment- modification; current drive experiment-upgrade; international collaboration; x-ray laser studies; spacecraft glow experiment; plasma processing: deposition and etching of thin films; theoretical studies; tokamak modeling; international thermonuclear experimental reactor; engineering department; project planning and safety office; quality assurance and reliability; technology transfer; administrative operations; PPPL patent invention disclosures for fiscal year 1990; graduate education; plasma physics; graduate education: plasma science and technology; science education program; and Princeton Plasma Physics Laboratory reports fiscal year 1990.

  12. Materials Science Laboratory

    Science.gov (United States)

    Jackson, Dionne

    2005-01-01

    The NASA Materials Science Laboratory (MSL) provides science and engineering services to NASA and Contractor customers at KSC, including those working for the Space Shuttle. International Space Station. and Launch Services Programs. These services include: (1) Independent/unbiased failure analysis (2) Support to Accident/Mishap Investigation Boards (3) Materials testing and evaluation (4) Materials and Processes (M&P) engineering consultation (5) Metrology (6) Chemical analysis (including ID of unknown materials) (7) Mechanical design and fabrication We provide unique solutions to unusual and urgent problems associated with aerospace flight hardware, ground support equipment and related facilities.

  13. Gait Analysis Laboratory

    Science.gov (United States)

    1976-01-01

    Complete motion analysis laboratory has evolved out of analyzing walking patterns of crippled children at Stanford Children's Hospital. Data is collected by placing tiny electrical sensors over muscle groups of child's legs and inserting step-sensing switches in soles of shoes. Miniature radio transmitters send signals to receiver for continuous recording of abnormal walking pattern. Engineers are working to apply space electronics miniaturization techniques to reduce size and weight of telemetry system further as well as striving to increase signal bandwidth so analysis can be performed faster and more accurately using a mini-computer.

  14. Propulsion Systems Laboratory, Bldg. 125

    Data.gov (United States)

    Federal Laboratory Consortium — The Propulsion Systems Laboratory (PSL) is NASAs only ground test facility capable of providing true altitude and flight speed simulation for testing full scale gas...

  15. Molecular Biomedical Imaging Laboratory (MBIL)

    Data.gov (United States)

    Federal Laboratory Consortium — The Molecular Biomedical Imaging Laboratory (MBIL) is adjacent-a nd has access-to the Department of Radiology and Imaging Sciences clinical imaging facilities. MBIL...

  16. Metallurgical Laboratory and Components Testing

    Data.gov (United States)

    Federal Laboratory Consortium — In the field of metallurgy, TTC is equipped to run laboratory tests on track and rolling stock components and materials. The testing lab contains scanning-electron,...

  17. The National Fire Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The National Fire Research Laboratory (NFRL) is adding a unique facility that will serve as a center of excellence for fireperformance of structures ranging in size...

  18. Tunison Laboratory of Aquatic Science

    Data.gov (United States)

    Federal Laboratory Consortium — Tunison Laboratory of Aquatic Science (TLAS), located in Cortland, New York, is a field station of the USGS Great Lakes Science Center (GLSC). TLAS was established...

  19. High Temperature Materials Laboratory (HTML)

    Data.gov (United States)

    Federal Laboratory Consortium — The six user centers in the High Temperature Materials Laboratory (HTML), a DOE User Facility, are dedicated to solving materials problems that limit the efficiency...

  20. How Reliable Is Laboratory Testing?

    Science.gov (United States)

    ... commonly used to determine the reliability of a clinical laboratory test. Two of these, accuracy and precision, reflect ... confidence your healthcare provider has in using the clinical laboratory. Accuracy and Precision Statistical measurements of accuracy and ...

  1. Remote Electro-Analytical Laboratory

    Directory of Open Access Journals (Sweden)

    Ratnanjali Gandhi

    2011-02-01

    Full Text Available Remote Laboratories are web based distance learning laboratories that have immense potential to disseminate technology in the area of practical science. These laboratories can be accessed through Internet. In the present paper, we will be discussing our experiences in setting up a remote analytical laboratory at our center. Further, we will discuss remote experiments in the area of electro-analytical chemistry & colorimetry and their role in strengthening the system of science education.

  2. Mobile Energy Laboratory Procedures

    Energy Technology Data Exchange (ETDEWEB)

    Armstrong, P.R.; Batishko, C.R.; Dittmer, A.L.; Hadley, D.L.; Stoops, J.L.

    1993-09-01

    Pacific Northwest Laboratory (PNL) has been tasked to plan and implement a framework for measuring and analyzing the efficiency of on-site energy conversion, distribution, and end-use application on federal facilities as part of its overall technical support to the US Department of Energy (DOE) Federal Energy Management Program (FEMP). The Mobile Energy Laboratory (MEL) Procedures establish guidelines for specific activities performed by PNL staff. PNL provided sophisticated energy monitoring, auditing, and analysis equipment for on-site evaluation of energy use efficiency. Specially trained engineers and technicians were provided to conduct tests in a safe and efficient manner with the assistance of host facility staff and contractors. Reports were produced to describe test procedures, results, and suggested courses of action. These reports may be used to justify changes in operating procedures, maintenance efforts, system designs, or energy-using equipment. The MEL capabilities can subsequently be used to assess the results of energy conservation projects. These procedures recognize the need for centralized NM administration, test procedure development, operator training, and technical oversight. This need is evidenced by increasing requests fbr MEL use and the economies available by having trained, full-time MEL operators and near continuous MEL operation. DOE will assign new equipment and upgrade existing equipment as new capabilities are developed. The equipment and trained technicians will be made available to federal agencies that provide funding for the direct costs associated with MEL use.

  3. Handbook of laboratory techniques

    International Nuclear Information System (INIS)

    The Nuclear Regulatory Authority in Argentina have laboratories of support to regulations functions on radiological and nuclear safety, safeguards and physical protection, that have a surface of 2950 m2 in the Ezeiza Atomic Center. The manual describes in seven chapters the different techniques developed and applied in the laboratories along four decades of existence. The chapter 1: Dedicated to the treatment of environmental samples, described the procedures associated with the different types of samples: deposits, waters, sediments, vegetables, milk, fish and diet. The chapter 2: Details 48 radiochemical techniques associated to the measurements of americium 241, carbon 16, strontium 90, iodine 129, plutonium, radium 226, radon, uranium, nickel and actinides. The chapter 3: Describes the measurements techniques of alpha and gamma spectrometry. The different techniques of biological and physical dosimetry are described in the chapters 5 and 6 respectively. The final chapter is dedicated the techniques of external and internal contamination. It s important to emphasize that this manual contains the standardized technologies that the Nuclear Regulatory Authority of Argentina submits regularly to international comparisons

  4. Laboratory Materials: Affordances or Constraints?

    Science.gov (United States)

    Jordan, Rebecca C.; Ruibal-Villasenor, Maria; Hmelo-Silver, Cindy E.; Etkina, Eugenia

    2011-01-01

    Laboratory instruction is critical to the understanding of biology and is a central piece of biological sciences instruction. Although much investigation has focused on the content of biology laboratory exercises, we contend that understanding the extent to which the laboratory materials can aid or limit experimental investigation is of equal…

  5. BioSecure: white paper for research in biometrics beyond BioSecure

    NARCIS (Netherlands)

    Schouten, B.A.M.; Deravi, F.; García-Mateo, C.; Tistarelli, M.; Snijder, M.; Meints, M.; Dittmann, J.

    2008-01-01

    This report is the output of a consultation process of various major stakeholders in the biometric community to identify the future biometrical research issues, an activity which employed not only researchers but representatives from the entire biometrical community, consisting of governments, indus

  6. Biossegurança e a enfermagem nos cuidados clínicos: contribuições para a saúde do trabalhador Biosecuridad y la enfermería en la atención clínica: contribuciones para promoción de la salud del trabajador Biosecurity and clinical care nursing: contributions for the promotion of worker's health

    Directory of Open Access Journals (Sweden)

    Samanta Rauber Gallas

    2010-10-01

    Full Text Available Estudo qualitativo que teve como objetivo investigar concepções e práticas de técnicos em enfermagem acerca da biossegurança e sua interface com os riscos biológicos, desenvolvido com vinte trabalhadores de uma unidade de cuidado clínico, de um hospital do interior do Rio Grande do Sul. Os dados foram coletados mediante entrevistas e observação sistemática. A análise temática foi a metodologia usada para o tratamento dos dados. A negligência dos trabalhadores quanto ao uso de Equipamentos de Proteção individual e a sobrecarga de trabalho são fatores de risco para os acidentes com material biológico. Sugerem-se parcerias entre os atores envolvidos no cuidado para a construção de ambientes saudáveis e responsabilização por negligências à biossegurança.Estudio cualitativo que tuvo como objetivo estudiar los conceptos y prácticas de los técnicos de enfermería sobre seguridad de la biotecnología y su interrelación con los factores biológicos, con veinte trabajadores desarrollado una unidad clínica de un hospital en el interior de Rio Grande do Sul Los datos fueron recolectados a través de entrevistas y observación sistemática. El análisis temático fue la metodología utilizada para el procesamiento de datos. La negligencia de sus empleados sobre el uso de equipos de protección individual y la sobrecarga de trabajo son factores de riesgo de accidentes con material biológico. Sugirió que las asociaciones entre los actores involucrados en el cuidado de la construcción de ambientes saludables y la responsabilidad por negligencia en materia de bioseguridad.Qualitative study that aimed at investigating concepts and practices of nursing technicians on biosecurity and its interface with biological hazards, with 20 workers developed a clinical care unit of a hospital in the interior of Rio Grande do Sul. Data were collected through interviews and systematic observation. Thematic analysis was the methodology used for

  7. An Organoleptic Laboratory Experiment

    Science.gov (United States)

    Risley, John M.

    1996-12-01

    Flavorings in foods and fragrances in personal care products is a topic often discussed in chemistry classes designed for the general education of non-science majors. A laboratory experiment has been designed to accompany the lecture topic. Compounds in ten different classes of organic molecules that are used in the fragrance and food industry are provided to students. Students whiff the vapors of each compound and describe the organoleptic properties using a set of terms utilized in the fragrance and food industry. A set of questions guides students to an understanding of the relationship between structure of molecules and smell. Students are permitted to create their own fragrance based on the results of the experiment. Student response has been favorable. The experiment rectifies misconceptions students have about structure and odor, and gives positive reinforcement to the lecture material.

  8. FORT Molecular Ecology Laboratory

    Science.gov (United States)

    Oyler-McCance, Sara J.; Stevens, P.D.

    2011-01-01

    The mission of the U.S. Geological Survey (USGS) at the Fort Collins Science Center Molecular Ecology Laboratory is to use the tools and concepts of molecular genetics to address a variety of complex management questions and conservation issues facing the management of the Nation's fish and wildlife resources. Together with our partners, we design and implement studies to document genetic diversity and the distribution of genetic variation among individuals, populations, and species. Information from these studies is used to support wildlife-management planning and conservation actions. Current and past studies have provided information to assess taxonomic boundaries, inform listing decisions made under the Endangered Species Act, identify unique or genetically depauperate populations, estimate population size or survival rates, develop management or recovery plans, breed wildlife in captivity, relocate wildlife from one location to another, and assess the effects of environmental change.

  9. Laboratory for Radiokrypton Dating

    Science.gov (United States)

    Lu, Z.; Bailey, K.; Jiang, W.; Müller, P.; O'Connor, T. P.; Zappala, J. C.

    2013-12-01

    Due to its simple production and transport processes in the terrestrial environment, the long-lived noble-gas isotope 81Kr (half-life = 230 kyr) is the ideal tracer for studying old water and ice in the age range of 10^5-10^6 years, a range beyond the reach of 14C. 81Kr dating, a concept pursued in the past four decades by numerous laboratories employing a variety of techniques, is now available for the first time to the earth science community at large. This is made possible by the development of ATTA-3 (Jiang et al., GCA 91, 1-6; 2012), an efficient and selective atom counter based on the Atom Trap Trace Analysis method (Chen et al., Science 286, 1139-1141; 1999). The instrument is capable of measuring both 81Kr/Kr and 85Kr/Kr ratios of environmental samples in the range of 10^-14-10^-10. For 81Kr-dating in the age range of 150 - 1,500 kyr, the required sample size is 5 - 10 micro-L STP of krypton gas, which can be extracted from approximately 100 - 200 kg of water or 40 - 80 kg of ice. For 85Kr/Kr analysis, the required sample size is generally smaller by an order of magnitude because of the isotope's higher initial abundance in the atmosphere. The Laboratory for Radiokrypton Dating is currently equipped to analyze up to 120 samples per year. With future equipment upgrades, this limit can be increased as demand grows. In the period since November 2011, the Laboratory has measured both 81Kr/Kr and 85Kr/Kr ratios in over 50 samples that had been extracted by collaborators from six different continents. The samples were from groundwater wells in the Great Artesian Basin (Australia), Guarani Aquifer (Brazil), and Locust Grove (Maryland); from brine wells of the Waste Isolation Pilot Plant (New Mexico); from geothermal steam vents in Yellowstone National Park; from near-surface ice at Taylor Glacier, Antarctica; and from deep mines in South Africa. Sample collection and purification was performed by groups including the University of Illinois at Chicago, University

  10. CLOSTRIDIA IN LABORATORY MEDICINE

    Directory of Open Access Journals (Sweden)

    Deepali P.

    2015-05-01

    Full Text Available OBJECTIVES : The significance of anaerobic bacteria as human pathogens is well documented. We undertook this preliminary study to detect anaerobic clostridial infections from clinical samples. MATERIAL AND METHODS : 58 clinical samples from various sites were obtained d epending upon diverse manifestations during five consecutive years. They were subjected to direct smears using Gram stain and cultured anaerobically using Robertson’s cooked meat broth. Culture smears were read after incubation from 48 hours to 5 days. RES ULTS: Out of the 58 samples only 18 samples (25.86% grew Gram positive spore bearing bacilli. Most of the samples showed polymicrobial flora. There was a preponderance of Gram positive bacilli with subterminal and central spores (55.55%. CONCLUSION: Alth ough diagnostic anaerobiasis is tedious and time consuming all clinical microbiology laboratories should start the work in view of the significance of anaerobic infections. KEYWORDS: Anaerobes, Clostridia, Gram stain, Robertson’s cooked meat broth.

  11. [ISO 15189 medical laboratory accreditation].

    Science.gov (United States)

    Aoyagi, Tsutomu

    2004-10-01

    This International Standard, based upon ISO/IEC 17025 and ISO 9001, provides requirements for competence and quality that are particular to medical laboratories. While this International Standard is intended for use throughout the currently recognized disciplines of medical laboratory services, those working in other services and disciplines will also find it useful and appropriate. In addition, bodies engaged in the recognition of the competence of medical laboratories will be able to use this International Standard as the basis for their activities. The Japan Accreditation Board for Conformity Assessment (AB) and the Japanese Committee for Clinical Laboratory Standards (CCLS) are jointly developing the program of accreditation of medical laboratories. ISO 15189 requirements consist of two parts, one is management requirements and the other is technical requirements. The former includes the requirements of all parts of ISO 9001, moreover it includes the requirement of conformity assessment body, for example, impartiality and independence from any other party. The latter includes the requirements of laboratory competence (e.g. personnel, facility, instrument, and examination methods), moreover it requires that laboratories shall participate proficiency testing(s) and laboratories' examination results shall have traceability of measurements and implement uncertainty of measurement. Implementation of ISO 15189 will result in a significant improvement in medical laboratories management system and their technical competence. The accreditation of medical laboratory will improve medical laboratory service and be useful for patients. PMID:15624503

  12. [ISO 15189 medical laboratory accreditation].

    Science.gov (United States)

    Aoyagi, Tsutomu

    2004-10-01

    This International Standard, based upon ISO/IEC 17025 and ISO 9001, provides requirements for competence and quality that are particular to medical laboratories. While this International Standard is intended for use throughout the currently recognized disciplines of medical laboratory services, those working in other services and disciplines will also find it useful and appropriate. In addition, bodies engaged in the recognition of the competence of medical laboratories will be able to use this International Standard as the basis for their activities. The Japan Accreditation Board for Conformity Assessment (AB) and the Japanese Committee for Clinical Laboratory Standards (CCLS) are jointly developing the program of accreditation of medical laboratories. ISO 15189 requirements consist of two parts, one is management requirements and the other is technical requirements. The former includes the requirements of all parts of ISO 9001, moreover it includes the requirement of conformity assessment body, for example, impartiality and independence from any other party. The latter includes the requirements of laboratory competence (e.g. personnel, facility, instrument, and examination methods), moreover it requires that laboratories shall participate proficiency testing(s) and laboratories' examination results shall have traceability of measurements and implement uncertainty of measurement. Implementation of ISO 15189 will result in a significant improvement in medical laboratories management system and their technical competence. The accreditation of medical laboratory will improve medical laboratory service and be useful for patients.

  13. The Laboratory for Terrestrial Physics

    Science.gov (United States)

    2003-01-01

    The Laboratory for Terrestrial Physics is dedicated to the advancement of knowledge in Earth and planetary science, by conducting innovative research using space technology. The Laboratory's mission and activities support the work and new initiatives at NASA's Goddard Space Flight Center (GSFC). The Laboratory's success contributes to the Earth Science Directorate as a national resource for studies of Earth from Space. The Laboratory is part of the Earth Science Directorate based at the GSFC in Greenbelt, MD. The Directorate itself is comprised of the Global Change Data Center (GCDC), the Space Data and Computing Division (SDCD), and four science Laboratories, including Laboratory for Terrestrial Physics, Laboratory for Atmospheres, and Laboratory for Hydrospheric Processes all in Greenbelt, MD. The fourth research organization, Goddard Institute for Space Studies (GISS), is in New York, NY. Relevant to NASA's Strategic Plan, the Laboratory ensures that all work undertaken and completed is within the vision of GSFC. The philosophy of the Laboratory is to balance the completion of near term goals, while building on the Laboratory's achievements as a foundation for the scientific challenges in the future.

  14. Short communication: A laboratory study to validate the impact of the addition of Alnus nepalensis leaf litter on carbon and nutrients mineralization in soil

    Directory of Open Access Journals (Sweden)

    GAURAV MISHRA

    2016-04-01

    Full Text Available Abstract. Mishra G, Giri K, Dutta A, Hazarika S and Borgohain P. 2015. A laboratory study to validate the impact of the addition of Alnus nepalensis leaf litter on carbon and nutrients mineralization in soil. Nusantara Bioscience 8: 5-7. Plant litter or residues can be used as soil amendment to maintain the carbon stock and soil fertility. The amount and rate of mineralization depends on biochemical composition of plant litter. Alnus nepalensis (Alder is known for its symbiotic nitrogen fixation and capability to restore fertility of degraded lands. A laboratory incubation experiment was conducted for 60 days under controlled conditions to validate the carbon and nutrients mineralization potential of alder litter. Soil fertility indicators, i.e. soil organic carbon (SOC, available nitrogen (N, available phosphorus (P, and available potassium (K were analyzed using standard procedures. Significant differences were observed in the soil properties after addition of litter. Nutrient composition of alder litter was found superior by providing significantly higher organic matter and helped in better nutrient cycling. Therefore, alder based land use system may be replicated in other degraded lands or areas for productivity enhancement which is important for sustaining biodiversity and soil fertility.

  15. Director, Laboratory Animal Care and Use Section

    Data.gov (United States)

    Federal Laboratory Consortium — The NIAMS Laboratory Animal Care and Use Section (LACU) provides support to all NIAMS Intramural Research Program (IRP) Branches and Laboratories using animals. The...

  16. Communications and Information Sharing (CIS) Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — TheCommunications and Information Sharing (CIS) Laboratory is a Public Safety interoperable communications technology laboratory with analog and digital radios, and...

  17. Laboratory instruction and subjectivity

    Directory of Open Access Journals (Sweden)

    Elisabeth Barolli

    1998-09-01

    Full Text Available The specific aspects which determined the way some groups of students conducted their work in a university laboratory, made us understand the articulation of these groups´s dynamics, from elements that were beyond the reach of cognition. In more specific terms the conduction and the maintenance of the groups student´s dynamics were explicited based on a intergame between the non conscious strategies, shared anonymously, and the efforts of the individuals in working based on their most objective task. The results and issues we have reached so far, using a reference the work developed by W.R.Bion, with therapeutical groups, gave us the possibility for understanding the dynamics of the student´s experimental work through a new approach that approximates the fields of cognition and subjectivity. This approximation led us to a deeper reflection about the issues which may be involved in the teaching process, particularly in situations which the teacher deals with the class, organised in groups.

  18. NSLS source development laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Ben-Zvi, I.; Blum, E.; Johnson, E.D. [and others

    1995-09-01

    The National Synchrotron Light Source (NSLS) has initiated an ambitious project to develop fourth generation radiation sources. To achieve this goal, the Source Development Laboratory (SDL) builds on the experience gained at the NSLS, and at the highly successful BNL Accelerator Test Facility. The SDL accelerator system will consist of a high brightness short pulse linac, a station for coherent synchrotron and transition radiation experiments, a short bunch storage ring, and an ultra-violet free electron laser utilizing the NISUS wiggler. The electrons will be provided by a laser photocathode gun feeding a 210 MeV S-band electron linac, with magnetic bunch compression at 80 MeV. Electron bunches as short as 100 {mu}m with 1 nC charge will be used for pump-probe experiments utilizing coherent transition radiation. Beam will also be injected into a compact storage ring which will be a source of millimeter wave coherent synchrotron radiation. The linac will also serve as the driver for an FEL designed to allow the study of various aspects of single pass amplifiers. The first FEL configuration will be as a self-amplified spontaneous emission (SASE) FEL at 900 nm. Seeded beam and sub-harmonic seeded beam operations will push the output wavelength below 200 nm. Chirped pulse amplification (CPA) operation will also be possible, and a planned energy upgrade (by powering a fifth linac section) to 310 MeV will extend the wavelength range of the FEL to below 100 nm.

  19. Remote Microelectronics Fabrication Laboratory MEFLab

    Directory of Open Access Journals (Sweden)

    Jan Machotka

    2008-07-01

    Full Text Available Over the last decade, there has been a move towards using remote laboratories in engineering education. The majority of these laboratories are static, involving limited user-controlled mechanical movements. The University of South Australia has developed such a laboratory, called NetLab that has been successfully utilized for teaching both on-campus and transnational programs in electrical and electronics engineering. Following this success, we are now developing a remote laboratory for microelectronic fabrication, MEFLab. The first stage of the development is a remote laboratory for visual inspection and testing of electronic circuits directly on the silicon wafer under a microscope which is normally conducted in a cleanroom. The major challenge of this project is the accurate positioning of micro-probes remotely over the internet. This paper presents the details of the setup of this new remote laboratory, with a particular emphasis on the development of the hardware, software and graphical user interface.

  20. Representações sociais da biossegurança por profissionais de enfermagem de um serviço de emergência Representaciones sociales de la bioseguridad por profesionales de enfermería de un servicio de emergencia Social representations of biosecurity by nursing professionals at an emergency service

    Directory of Open Access Journals (Sweden)

    Andréia Rodrigues Moura da Costa Valle

    2008-06-01

    infección hospitalaria fue objetivada a través de las evocaciones, enfermedad y basura. Se considera finalmente, que la Bioseguridad aún no fue incorporada como un conjunto de medidas necesarias al control de la infección hospitalaria, especialmente del punto de vista social y psicológico, predominando los aspectos epidemiológicos, biológicos y económicos.The objective of the study was to learn the Social Representations of Biosecurity elaborated by nursing professionals and to analyze how these representations influence the practice and quality of the assistance given. This is an exploratory study based on the Theory of Social Representations, and was done at an emergency service in a public hospital with 60 nursing professionals. The data was collected through the technique of Free Word Association by using the words as stimulus: biosecurity and hospital infection. The data was processed on the Tri Deux Mots software and a Correspondence Factor Analysis was done. The results showed that biosecurity was seen through the evocations disposable, anti-septic, and immunization, while hospital infection was seen through the evocations disease and uncleanness. Finally, it should be noted that Biosecurity has still not been incorporated as a group of measures necessary to control hospital infections. The economical, biological and epidemiological aspects predominate especially from the social and psychological point of view.

  1. Whole Class Laboratories: More Examples

    Science.gov (United States)

    Kouh, Minjoon

    2016-03-01

    Typically, introductory physics courses are taught with a combination of lectures and laboratories in which students have opportunities to discover the natural laws through hands-on activities in small groups. This article reports the use of Google Drive, a free online document-sharing tool, in physics laboratories for pooling experimental data from the whole class. This pedagogical method was reported earlier, and the present article offers a few more examples of such "whole class" laboratories.

  2. User facilities at federal laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Baron, S.; Marcuse, W.

    1988-04-01

    Recent initiatives by the Congress and the Administration have been directed to improving American industrial competitiveness. One of these initiatives is directed to encouraging industrial users to avail themselves of special facilities existent at federal laboratories. The facilities available at the National Bureau of Standards (NBS) and seven Department of Energy (DOE) laboratories are presented here. One facility at each Laboratory is described in detail, the remainder are listed with the names and telephone numbers of individuals to contact for further information.

  3. [Laboratory accreditation and proficiency testing].

    Science.gov (United States)

    Kuwa, Katsuhiko

    2003-05-01

    ISO/TC 212 covering clinical laboratory testing and in vitro diagnostic test systems will issue the international standard for medical laboratory quality and competence requirements, ISO 15189. This standard is based on the ISO/IEC 17025, general requirements for competence of testing and calibration laboratories and ISO 9001, quality management systems-requirements. Clinical laboratory services are essential to patient care and therefore should be available to meet the needs of all patients and clinical personnel responsible for human health care. If a laboratory seeks accreditation, it should select an accreditation body that operates according to this international standard and in a manner which takes into account the particular requirements of clinical laboratories. Proficiency testing should be available to evaluate the calibration laboratories and reference measurement laboratories in clinical medicine. Reference measurement procedures should be of precise and the analytical principle of measurement applied should ensure reliability. We should be prepared to establish a quality management system and proficiency testing in clinical laboratories. PMID:12806918

  4. Ethical Inspection about laboratory animals.

    Science.gov (United States)

    Yang, Nai-bin; Pan, Xiao-jun; Cheng, Jing-jing; Lin, Jia-qiang; Zhu, Jia-yin

    2015-11-01

    Laboratory animals and animal experiments are foundations and important support conditions for life sciences, especially for medical research. The animal experiments have drawn extensive attention from the society because of the ethical issue. This paper takes Wenzhou Medical University as an example to give a brief introduction to the ethical review about laboratory animals in the university so as to further draw attention and concerns from the public about the ethical issue of laboratory animals. We successively introduce its scientific projects, nurturing environment and ethical review of laboratory animals. PMID:27215017

  5. Ground Systems Concepts Laboratory (GSCL)

    Data.gov (United States)

    Federal Laboratory Consortium — GSCL consists of high-performance CAD stations and associated software located in a secure facility. Capabilities: The GSCL provides infrastructure that allows the...

  6. Communication Systems Analysis Laboratory (CSAL)

    Data.gov (United States)

    Federal Laboratory Consortium — CSAL conducts electronic warfare investigations of radio frequency communication systems with respect to current and emerging electronic warfare threats. CSAL uses...

  7. Space Solar Cell Characterization Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Measures, characterizes, and analyzes photovoltaic materials and devices. The primary focus is the measurement and characterization of solar cell response...

  8. Survivability Armor Ballistic Laboratory (SABL)

    Data.gov (United States)

    Federal Laboratory Consortium — The SABL provides independent analysis, ballistic testing, data collection, data reduction and qualification of current and advanced armors. Capabilities: The SABL...

  9. Ethical Inspection about laboratory animals.

    Science.gov (United States)

    Yang, Nai-bin; Pan, Xiao-jun; Cheng, Jing-jing; Lin, Jia-qiang; Zhu, Jia-yin

    2015-11-01

    Laboratory animals and animal experiments are foundations and important support conditions for life sciences, especially for medical research. The animal experiments have drawn extensive attention from the society because of the ethical issue. This paper takes Wenzhou Medical University as an example to give a brief introduction to the ethical review about laboratory animals in the university so as to further draw attention and concerns from the public about the ethical issue of laboratory animals. We successively introduce its scientific projects, nurturing environment and ethical review of laboratory animals.

  10. Thermal Manikins & Clothing Biophysics Laboratories

    Data.gov (United States)

    Federal Laboratory Consortium — Five biophysical evaluation chambers containing fully sensored, articulated, moveable copper manikins, and other metallic models of feet and hands are available for...

  11. Laboratory for Radiokrypton Dating

    Science.gov (United States)

    Zappala, J. C.; Jiang, W.; Bailey, K. G.; Lu, Z. T.; Mueller, P.; O'Connor, T. P.

    2015-12-01

    Due to its simple production and transport in the terrestrial environment, 81Kr (half-life = 230,000 yr) is the ideal tracer for old water and ice with mean residence times in the range of 105-106 years, a range beyond the reach of 14C. 81Kr-dating is now available to the earth science community at large thanks to the development of an efficient and selective atom counter based on the Atom Trap Trace Analysis (ATTA) method. ATTA is a laser-based atom counting method where individual neutral atoms of the desired isotope are selectively captured by laser beams, and their fluorescence detected via a CCD camera. ATTA is unique among trace analysis techniques in that it is free of interferences from any other isotopes, isobars, atomic or molecular species. The ATTA instrument at Argonne's Laboratory for Radiokrypton Dating is capable of measuring both 81Kr/Kr and 85Kr/Kr ratios of environmental samples in the range of 10-14-10-10. For 81Kr-dating in the age range of 150 kyr - 1500 kyr, the required sample size is 5 micro-L STP of krypton gas, which can be extracted from approximately 100 kg of water or 40 kg of ice. For 85Kr/Kr analysis, the sample size can be smaller by an order of magnitude. We are continually developing the method towards higher counting efficiency, smaller sample sizes requirements, and higher sample throughput rates. In the past four years, we have performed radiokrypton analysis of over 150 groundwater and ice samples extracted by collaborators from all seven continents. Sample collection and purification was performed by groups including the University of Chicago, the University of Illinois at Chicago, the University of Bern, and the International Atomic Energy Agency. This work is supported by the U.S. DOE, Office of Nuclear Physics, under contract DE-AC02-06CH11357.

  12. Laboratory diagnosis of thalassemia.

    Science.gov (United States)

    Brancaleoni, V; Di Pierro, E; Motta, I; Cappellini, M D

    2016-05-01

    The thalassemias can be defined as α- or β-thalassemias depending on the defective globin chain and on the underlying molecular defects. The recognition of carriers is possible by hematological tests. Both α- and β-thalassemia carriers (heterozygotes) present with microcytic hypochromic parameters with or without mild anemia. Red cell indices and morphology followed by separation and measurement of Hb fractions are the basis for identification of carriers. In addition, iron status should be ascertained by ferritin or zinc protoporphyrin measurements and the iron/total iron-binding capacity/saturation index. Mean corpuscular volume and mean corpuscular hemoglobin are markedly reduced (mean corpuscular volume: 60-70 fl; MCH: 19-23 pg) in β-thalassemia carriers, whereas a slight to relevant reduction is usually observed in α-carriers. HbA2 determination is the most decisive test for β-carrier detection although it can be disturbed by the presence of δ-thalassemia defects. In α-thalassemia, HbA2 can be lower than normal and it assumes significant value when iron deficiency is excluded. Several algorithms have been introduced to discriminate from thalassemia carriers and subjects with iron-deficient anemia; because the only discriminating parameter is the red cell counts, these formulas must be used consciously. Molecular analysis is not required to confirm the diagnosis of β-carrier, but it is necessary to confirm the α-thalassemia carrier status. The molecular diagnosis is essential to predict severe transfusion-dependent and intermediate-to-mild non-transfusion-dependent cases. DNA analysis on chorionic villi is the approach for prenatal diagnosis and the methods are the same used for mutations detection, according to the laboratory facilities and expertise. PMID:27183541

  13. Australia's marine virtual laboratory

    Science.gov (United States)

    Proctor, Roger; Gillibrand, Philip; Oke, Peter; Rosebrock, Uwe

    2014-05-01

    In all modelling studies of realistic scenarios, a researcher has to go through a number of steps to set up a model in order to produce a model simulation of value. The steps are generally the same, independent of the modelling system chosen. These steps include determining the time and space scales and processes of the required simulation; obtaining data for the initial set up and for input during the simulation time; obtaining observation data for validation or data assimilation; implementing scripts to run the simulation(s); and running utilities or custom-built software to extract results. These steps are time consuming and resource hungry, and have to be done every time irrespective of the simulation - the more complex the processes, the more effort is required to set up the simulation. The Australian Marine Virtual Laboratory (MARVL) is a new development in modelling frameworks for researchers in Australia. MARVL uses the TRIKE framework, a java-based control system developed by CSIRO that allows a non-specialist user configure and run a model, to automate many of the modelling preparation steps needed to bring the researcher faster to the stage of simulation and analysis. The tool is seen as enhancing the efficiency of researchers and marine managers, and is being considered as an educational aid in teaching. In MARVL we are developing a web-based open source application which provides a number of model choices and provides search and recovery of relevant observations, allowing researchers to: a) efficiently configure a range of different community ocean and wave models for any region, for any historical time period, with model specifications of their choice, through a user-friendly web application, b) access data sets to force a model and nest a model into, c) discover and assemble ocean observations from the Australian Ocean Data Network (AODN, http://portal.aodn.org.au/webportal/) in a format that is suitable for model evaluation or data assimilation, and

  14. The direction of the laboratories

    International Nuclear Information System (INIS)

    In the scope of the presentation of the 1988 Polytechnic School (France) research programs, the activities concerning each laboratory, are summarized. Several aspects of the programs are considered: the main projects, the results, the planned researches and the technical means. The personnel of the laboratory, their number in the different categories, the published papers, the patents and the thesis are included

  15. Whole Class Laboratories: More Examples

    Science.gov (United States)

    Kouh, Minjoon

    2016-01-01

    Typically, introductory physics courses are taught with a combination of lectures and laboratories in which students have opportunities to discover the natural laws through hands-on activities in small groups. This article reports the use of Google Drive, a free online document-sharing tool, in physics laboratories for pooling experimental data…

  16. Laboratory solvent reuse -- Liquid chromatography

    Energy Technology Data Exchange (ETDEWEB)

    Quinlin, W.T.; Schaffer, C.L.

    1992-11-01

    The objective of this work was to develop a method for reduction of waste solvent in the Process Engineering Chemistry Laboratory. The liquid chromatographs are the largest generators of explosive-contaminated waste in the laboratory. We developed a successful process for the reuse of solvents from the liquid chromatographs and demonstrated the utility of the process in the assay of hexanitrostilbene.

  17. The Virtual Robotics Laboratory; TOPICAL

    International Nuclear Information System (INIS)

    The growth of the Internet has provided a unique opportunity to expand research collaborations between industry, universities, and the national laboratories. The Virtual Robotics Laboratory (VRL) is an innovative program at Oak Ridge National Laboratory (ORNL) that is focusing on the issues related to collaborative research through controlled access of laboratory equipment using the World Wide Web. The VRL will provide different levels of access to selected ORNL laboratory secondary education programs. In the past, the ORNL Robotics and Process Systems Division has developed state-of-the-art robotic systems for the Army, NASA, Department of Energy, Department of Defense, as well as many other clients. After proof of concept, many of these systems sit dormant in the laboratories. This is not out of completion of all possible research topics. but from completion of contracts and generation of new programs. In the past, a number of visiting professors have used this equipment for their own research. However, this requires that the professor, and possibly his/her students, spend extended periods at the laboratory facility. In addition, only a very exclusive group of faculty can gain access to the laboratory and hardware. The VRL is a tool that enables extended collaborative efforts without regard to geographic limitations

  18. A laboratory animal science pioneer.

    Science.gov (United States)

    Kostomitsopoulos, Nikolaos

    2014-11-01

    Nikolaos Kostomitsopoulos, DVM, PhD, is Head of Laboratory Animal Facilities and Designated Veterinarian, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece. Dr. Kostomitsopoulos discusses his successes in implementing laboratory animal science legislation and fostering collaboration among scientists in Greece.

  19. Detection of Female Genital Tuberculosis by using Endo-Ovarian Tissue Biopsy - See more at: http://sciencebeingjournal.com/octa-journal-biosciences/detection-female-genital-tuberculosis-using-endo-ovarian-tissue-biopsy#sthash.Z5J55goq.dpuf

    Directory of Open Access Journals (Sweden)

    Venkanna Bhanothu

    2013-12-01

    Full Text Available Female genital tuberculosis is a symptomless disease accidentally revealed during inquiry for infertility. Inefficacy of costly tests and negligence have intended for underestimation of the disease. Therefore we have chosen to reevaluate the role of conventional and genotypic methods in the detection of female genital tuberculosis by using endometrial tissue biopsy, ovarian tissue biopsy and pelvic aspirated fluids taken as samples from infertile women during hysteroscopy or laparoscopy. It is a prospective case-control study. Premenstrual endometrial tissue biopsy, ovarian tissue biopsy and pelvic aspirated fluids were collected from 202 infertile women suspected of having genital tuberculosis on laparoscopic examination and from 100 normal women of reproductive age, suspected of having genital tuberculosis. All patients were subjected to laboratory examinations by the conventional/ phenotypic methods to compare with multi gene/ multi-primer based PCR method using four set of primers for the detection of Mycobacterium tuberculosis in a single tube reaction. The conventional methods had 99% to 100% specificity with a low sensitivity, ranging from 21.78% to 42.08% while H & E staining had a sensitivity of 51.48%. In comparison, multi-gene PCR method was found to have a much higher sensitivity of 42.57% with MTB64 gene, 86.13% with TRC4 element, 99.01% with 19kDa antigen (131bp and 100% with MPT59 α-antigen/32kDa protein (506bp gene. The specificity of multi gene PCR was 100%. In conclusions, since 32kDa protein is encoded by Mycobacterium genus specific gene, we suggest 19kDa antigen in combination with TRC4 element could be a successful multi-gene/multi-primer PCR method in the diagnosis of FGTB

  20. Virtual robotics laboratory for research

    Science.gov (United States)

    McKee, Gerard T.

    1995-09-01

    We report on work currently underway to put a robotics laboratory onto the Internet in support of teaching and research in robotics and artificial intelligence in higher education institutions in the UK. The project is called Netrolab. The robotics laboratory comprises a set of robotics resources including a manipulator, a mobile robot with an on-board monocular active vision head and a set of sonar sensing modules, and a set of laboratory cameras to allow the user to see into the laboratory. The paper will report on key aspect of the project aimed at using multimedia tools and object-oriented techniques to network the robotics resources and to allow them to be configured into complex teaching and experimental modules. The paper will outline both the current developments of Netrolab and provide a perspective on the future development of networked virtual laboratories for research.