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Sample records for bioscience nuclear microscopy

  1. The Bioscience Nuclear Microscopy Program at LLNL

    Energy Technology Data Exchange (ETDEWEB)

    Bench, G.; Freeman, S.; Roberts, M.; Sideras-Haddad, E.

    1996-12-31

    Since initiation in mid 1994, a bioscience nuclear microscopy program at Livermore has enabled collaboration with bio-scientists on a variety of projects requiring quantitative elemental microanalysis. For microprobe analysis a combination of PIXE and STIM are typically used; respectively generating element distribution maps with micron scale spatial resolution, and projected densities and histological information with sub-micron spatial resolution. Current studies demonstrate the applicability of nuclear microscopy (particularly when combined with other analysis techniques) in environmental tracing, toxicology, carcinogenesis, and structural biology. The program currently uses {approximately}10 percent of the available time on a 10 MV tandem accelerator that is also applied to a variety of Accelerator Mass Spectrometry and other microprobe programs. The completion of a dedicated nuclear microprobe system, using a 5 SDH NEC 1.7 MV tandem accelerator and employing several energy dispersive x-ray detectors to improve x-ray counting rates, promises increased accelerator access, greater sample throughput and continued expansion of the program.

  2. SBBN 2010: 7. Congress of the Brazilian Society of Nuclear Biosciences. Radiations in biosciences: advances and trends

    International Nuclear Information System (INIS)

    2010-01-01

    Advance and new perspectives related to the use of ionizing and no ionizing radiations in nuclear biosciences are presented. Multidisciplinary approach, including radiopharmacy, radioprotection and dosimetry, cytogenetic, biosafety, radioecology, environmental toxicology are studied. Topics of Nuclear medicine, radiotherapy and image diagnosis, such as computerized tomography, PET scan, phantoms, biomedical radiography, are reported. Use of radioisotopes, evaluation of radiation dose rates, radiation dose distribution, radiation monitoring is considered. Environmental impact of radiation are also in human beings, animals and for several purposes are analyzed. (MAC)

  3. Nuclear microscopy of biological specimens

    International Nuclear Information System (INIS)

    Watt, F.; Grime, G.W.; Brook, A.J.; Gadd, G.M.; Perry, C.C.; Pearce, R.B.; Turnau, K.; Watkinson, S.C.

    1991-01-01

    Recent developments in technology have enabled the scanning proton microprobe to scan at submicron spatial resolution on a routine basis. The use of the powerful combination of techniques PIXE (proton induced X-ray emission), nuclear (or Rutherford) backscattering (RBS), and secondary electron detection operating at this resolution will open up new areas in many scientific disciplines. This paper describes some of the work carried out in the biological sciences over the last year, using the Oxford SPM facility. Collaborations with biological scientists have drawn attention to the wealth of information that can be derived when these techniques are applied to micro-organisms, cells and plant tissue. Briefly described here are investigations into the uptake of heavy metals by the alga Pandorina morum, the structure of the diatom Stephanopyxis turris, the presence of various types of crystal structures within the cells of Spirogyra, the heavy metal uptake of a mycorrhizal fungus present in the bracken (Pteridium aquilinum) root, the role of sphagnum moss in the absorption of inorganic elements, the measurement of heavy metals in environmentally-adapted cells of the yeast Saccharomyces cerevisiae, and the elemental distribution in the growing tip of a spore from the plant Equisetum arvense, with special emphasis placed on the visual interpretation of the elemental and secondary-electron maps provided by the nuclear microscopical techniques. (orig.)

  4. Nuclear microscopy of biological specimens

    Energy Technology Data Exchange (ETDEWEB)

    Watt, F.; Grime, G.W. (Nuclear Physics Lab., Univ. of Oxford (UK)); Brook, A.J. (Clore Lab., Univ. of Buckingham (UK)); Gadd, G.M. (Dept. of Biological Sciences, Univ. of Dundee (UK)); Perry, C.C. (Dept. of Chemistry, Brunel Univ., Uxbridge (UK)); Pearce, R.B. (Dept. of Plant Sciences, Univ. of Oxford (UK)); Turnau, K. (Dept. of Botany, Jagiellonian Univ., Krakow (Poland)); Watkinson, S.C. (Dept. of Plant Sciences, Univ. of Oxford (UK))

    1991-03-01

    Recent developments in technology have enabled the scanning proton microprobe to scan at submicron spatial resolution on a routine basis. The use of the powerful combination of techniques PIXE (proton induced X-ray emission), nuclear (or Rutherford) backscattering (RBS), and secondary electron detection operating at this resolution will open up new areas in many scientific disciplines. This paper describes some of the work carried out in the biological sciences over the last year, using the Oxford SPM facility. Collaborations with biological scientists have drawn attention to the wealth of information that can be derived when these techniques are applied to micro-organisms, cells and plant tissue. Briefly described here are investigations into the uptake of heavy metals by the alga Pandorina morum, the structure of the diatom Stephanopyxis turris, the presence of various types of crystal structures within the cells of Spirogyra, the heavy metal uptake of a mycorrhizal fungus present in the bracken (Pteridium aquilinum) root, the role of sphagnum moss in the absorption of inorganic elements, the measurement of heavy metals in environmentally-adapted cells of the yeast Saccharomyces cerevisiae, and the elemental distribution in the growing tip of a spore from the plant Equisetum arvense, with special emphasis placed on the visual interpretation of the elemental and secondary-electron maps provided by the nuclear microscopical techniques. (orig.).

  5. SBBN 2010: 7. Congress of the Brazilian Society of Nuclear Biosciences. Radiations in biosciences: advances and trends; SBBN 2010: 7. Congresso da Sociedade Brasileira de Biociencias Nucleares. Radiacoes em biociencias: avancos e perspectivas

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    Advance and new perspectives related to the use of ionizing and no ionizing radiations in nuclear biosciences are presented. Multidisciplinary approach, including radiopharmacy, radioprotection and dosimetry, cytogenetic, biosafety, radioecology, environmental toxicology are studied. Topics of Nuclear medicine, radiotherapy and image diagnosis, such as computerized tomography, PET scan, phantoms, biomedical radiography, are reported. Use of radioisotopes, evaluation of radiation dose rates, radiation dose distribution, radiation monitoring is considered. Environmental impact of radiation are also in human beings, animals and for several purposes are analyzed. (MAC)

  6. Electron microscopy of nuclear zirconium alloys

    International Nuclear Information System (INIS)

    Versaci, R.A.; Ipohorski, Miguel

    1986-01-01

    Transmission electron microscopy observations of the microstructure of zirconium alloys used in fuel sheaths of nuclear power reactors are reported. Specimens were observed after different thermal and mechanical treatment, similar to those actually used during fabrication of the sheaths. Electron micrographs and electron diffraction patterns of second phase particles present in zircaloy-2 and zircaloy-4 were also obtained, as well as some characteristic parameters. Images of oxides and hydrides most commonly present in zirconium alloys are also shown. Finally, the structure of a Zr-2,5Nb alloy used in CANDU reactors pressure tubes, is observed by electron microscopy. (Author) [es

  7. Nuclear microscopy of sperm cell elemental structure

    Energy Technology Data Exchange (ETDEWEB)

    Bench, G.S.; Balhorn, R.; Friz, A.M.; Freeman, S.P.H.T.

    1994-09-28

    Theories suggest there is a link between protamine concentrations in individual sperm and male fertility. Previously, biochemical analyses have used pooled samples containing millions of sperm to determine protamine concentrations. These methods have not been able to determine what percentage of morphologically normal sperm are biochemically defective and potentially infertile. Nuclear microscopy has been utilized to measure elemental profiles at the single sperm level. By measuring the amount of phosphorus and sulfur, the total DNA and protamine content in individual sperm from fertile bull and mouse semen have been determined. These values agree with results obtained from other biochemical analyses. Nuclear microscopy shows promise for measuring elemental profiles in the chromatin of individual sperm. The technique may be able to resolve theories regarding the importance of protamines to male fertility and identify biochemical defects responsible for certain types of male infertility.

  8. Nuclear microscopy of rat colon epithelial cells

    Science.gov (United States)

    Ren, M.; Rajendran, Reshmi; Ng, Mary; Udalagama, Chammika; Rodrigues, Anna E.; Watt, Frank; Jenner, Andrew Michael

    2011-10-01

    Using Nuclear microscopy, we have investigated iron distributions in the colons of Sprague Dawley rats, in order to elucidate heme uptake. Four groups of five Sprague Dawley rats (mean weight 180 g) were fed different purified diets containing either heme diet (2.5% w/w hemoglobin), high fat diet (HFD) (18% w/w fat, 1% w/w cholesterol), 'western' diet (combination of hemoglobin 2.5% and 18% fat, 1% cholesterol) or control diet (7% w/w fat). After 4 weeks, animals were sacrificed by exsanguination after anaesthesia. Thin sections of frozen colon tissue were taken, freeze dried and scanned using nuclear microscopy utilising the techniques PIXE, RBS and STIM. The new data acquisition system (IonDaq) developed in CIBA was used to obtain high resolution images and line scans were used to map the iron distributions across the colon boundaries. The nuclear microscope results indicate that when HFD is given in addition to heme, the iron content of the epithelial cells that line the colon decreases, and the zinc in the smooth muscle wall increases. This implies that the level of heme and fat in diet has an important role in colon health, possibly by influencing epithelial cells directly or changing luminal composition such as bacterial flora or levels of metabolites and cytotoxins.

  9. Nuclear microscopy of rat colon epithelial cells

    Energy Technology Data Exchange (ETDEWEB)

    Ren, M., E-mail: phyrenmq@nus.edu.sg [Centre for Ion Beam Applications (CIBA), Department of Physics, National University of Singapore, Singapore 117542 (Singapore); Rajendran, Reshmi [Lab of Molecular Imaging, Singapore Bioimaging Consotium, 11 Biopolis Way, 02-02 Helios, Singapore 138667 (Singapore); Ng, Mary [Department of Pharmacology, National University of Singapore (Singapore); Udalagama, Chammika; Rodrigues, Anna E.; Watt, Frank [Centre for Ion Beam Applications (CIBA), Department of Physics, National University of Singapore, Singapore 117542 (Singapore); Jenner, Andrew Michael [Illawara Health and Medical Research Institute (IHMRI), University of Wollongong, NSW 2522 (Australia)

    2011-10-15

    Using Nuclear microscopy, we have investigated iron distributions in the colons of Sprague Dawley rats, in order to elucidate heme uptake. Four groups of five Sprague Dawley rats (mean weight 180 g) were fed different purified diets containing either heme diet (2.5% w/w hemoglobin), high fat diet (HFD) (18% w/w fat, 1% w/w cholesterol), 'western' diet (combination of hemoglobin 2.5% and 18% fat, 1% cholesterol) or control diet (7% w/w fat). After 4 weeks, animals were sacrificed by exsanguination after anaesthesia. Thin sections of frozen colon tissue were taken, freeze dried and scanned using nuclear microscopy utilising the techniques PIXE, RBS and STIM. The new data acquisition system (IonDaq) developed in CIBA was used to obtain high resolution images and line scans were used to map the iron distributions across the colon boundaries. The nuclear microscope results indicate that when HFD is given in addition to heme, the iron content of the epithelial cells that line the colon decreases, and the zinc in the smooth muscle wall increases. This implies that the level of heme and fat in diet has an important role in colon health, possibly by influencing epithelial cells directly or changing luminal composition such as bacterial flora or levels of metabolites and cytotoxins.

  10. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. VINCENZO IERARDI. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 623-636 Article. Klebsiella pneumoniae antibiotic resistance identified by atomic force microscopy · VINCENZO IERARDI PAOLO DOMENICHINI SILVIA REALI GIAN MARCO ...

  11. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. SILVIA REALI. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 623-636 Article. Klebsiella pneumoniae antibiotic resistance identified by atomic force microscopy · VINCENZO IERARDI PAOLO DOMENICHINI SILVIA REALI GIAN MARCO ...

  12. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. GIAN MARCO CHIAPPARA. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 623-636 Article. Klebsiella pneumoniae antibiotic resistance identified by atomic force microscopy · VINCENZO IERARDI PAOLO DOMENICHINI SILVIA REALI GIAN ...

  13. Nuclear microscopy in medical research. Investigations into degenerative diseases

    Energy Technology Data Exchange (ETDEWEB)

    Makjanic, J.; Thong, P.; Watt, F. [National University of Singapore (Singapore). Dept. of Physics

    1997-03-01

    The high energy (1-4MeV) focused ion beam (nuclear microbeam) has found uses in many scientific disciplines through a wide variety of ion beam based techniques. Of the many techniques available, the powerful combination of Particle Induced X-Ray Emission (PIXE), Rutherford Backscattering Spectrometry (RBS), and Scanning Transmission Ion Microscopy (STIM) is proving to be extremely useful, particularly in the characterisation and elemental analysis of thin specimens. In this paper we briefly review these ion beam techniques, as well as the hardware required for their application. Finally, we describe the application of the PIXE, RBS and STIM techniques in conjunction with a scanning focused 2MeV proton microbeam (nuclear microscopy). The examples chosen to illustrate the potential of nuclear microscopy are recent investigations into the degenerative diseases atherosclerosis (coronary heart disease), Parkinson`s disease and Alzheimer`s disease. (author)

  14. Instruments for radiation measurement in biosciences. Series 3. radioluminography. 11. Application of imaging plate in transmission electron microscopy

    International Nuclear Information System (INIS)

    Oikawa, Tetsuo

    1999-01-01

    Properties and application of the imaging plate (IP) in transmission electron microscopy (TEM) are reviewed. TEM has the resolution level of around 0.2 nm, which enables direct observation of molecules and atoms. In TEM, there are such recording systems as photographic film, TV camera, slow-scan CCD camera and IP. IP, to the electron beam, has the higher sensitivity than the film and has the broad dynamic range. Linearity between the input beam intensity and output signal is good, which makes it possible to record the image even with the small electron dose. Signal/noise ratio and detective quantum efficiency are important factors for precise image analysis. Fading phenomenon is a defect of IP, which weakens the signal output as time passing. For instance of application, IP is used for imaging of AgBr crystal fragile to strong electron beam required for the film. IP is necessary for quantitative analysis of TEM images and for the recently developed energy-filter TEM. (K.H.)

  15. Superresolution Microscopy of the Nuclear Envelope and Associated Proteins.

    Science.gov (United States)

    Xie, Wei; Horn, Henning F; Wright, Graham D

    2016-01-01

    Superresolution microscopy is undoubtedly one of the most exciting technologies since the invention of the optical microscope. Capable of nanometer-scale resolution to surpass the diffraction limit and coupled with the versatile labeling techniques available, it is revolutionizing the study of cell biology. Our understanding of the nucleus, the genetic and architectural center of the cell, has gained great advancements through the application of various superresolution microscopy techniques. This chapter describes detailed procedures of multichannel superresolution imaging of the mammalian nucleus, using structured illumination microscopy and single-molecule localization microscopy.

  16. Microscopy

    Science.gov (United States)

    Patricia A. Moss; Les Groom

    2001-01-01

    Microscopy is the study and interpretation of images produced by a microscope. "Interpretation" is the keyword, because the microscope enables one to see structures that are too small or too close together to be resolved by the unaided eye. (The human eye cannot separate two points or lines that are closer together than 0.1 mm.) it is important to...

  17. Nuclear uptake of ultrasmall gold-doxorubicin conjugates imaged by fluorescence lifetime imaging microscopy (FLIM) and electron microscopy

    Science.gov (United States)

    Zhang, Xuan; Shastry, Sathvik; Bradforth, Stephen E.; Nadeau, Jay L.

    2014-11-01

    Fluorescence lifetime imaging microscopy (FLIM) has been used to image free and encapsulated doxorubicin (Dox) uptake into cells, since interaction of Dox with DNA leads to a characteristic lifetime change. However, none of the reported Dox conjugates were able to enter cell nuclei. In this work, we use FLIM to show nuclear uptake of 2.7 nm mean diameter Au nanoparticles conjugated to Dox. The pattern of labelling differed substantially from what was seen with free Dox, with slower nuclear entry and stronger cytoplasmic labelling at all time points. As the cells died, the pattern of labelling changed further as intracellular structures disintegrated, consistent with association of Au-Dox to membranes. The patterns of Au distribution and intracellular structure changes were confirmed using electron microscopy, and indicate different mechanisms of cytotoxicity with stable Au-Dox conjugates compared to Dox alone. Such conjugates are promising tools for overcoming resistance in Dox-resistant cancers.Fluorescence lifetime imaging microscopy (FLIM) has been used to image free and encapsulated doxorubicin (Dox) uptake into cells, since interaction of Dox with DNA leads to a characteristic lifetime change. However, none of the reported Dox conjugates were able to enter cell nuclei. In this work, we use FLIM to show nuclear uptake of 2.7 nm mean diameter Au nanoparticles conjugated to Dox. The pattern of labelling differed substantially from what was seen with free Dox, with slower nuclear entry and stronger cytoplasmic labelling at all time points. As the cells died, the pattern of labelling changed further as intracellular structures disintegrated, consistent with association of Au-Dox to membranes. The patterns of Au distribution and intracellular structure changes were confirmed using electron microscopy, and indicate different mechanisms of cytotoxicity with stable Au-Dox conjugates compared to Dox alone. Such conjugates are promising tools for overcoming resistance in

  18. X-ray tomography as a complementary technique to nuclear microscopy for biomedical applications

    Energy Technology Data Exchange (ETDEWEB)

    Gomez-Morilla, Inmaculada [Institut fuer Stroemungsmechanik, Technische Universitaet Dresden, Lehrstuhl fuer Magnetofluiddynamik, Georg-Baehr-Str. 3, 01069 Dresden (Germany)], E-mail: inmaculada.gomez-morilla@tu-dresden.de; Pinheiro, Teresa [Laboratorio de Feixes de Ioes, Instituto Tecnologico e Nuclear, E.N. 10, 2685-953 Sacavem (Portugal); Odenbach, Stefan [Institut fuer Stroemungsmechanik, Technische Universitaet Dresden, Lehrstuhl fuer Magnetofluiddynamik, Georg-Baehr-Str. 3, 01069 Dresden (Germany); Alcala, Maria Dolores Ynsa [Centro de Microanalisis de Materiales, Universidad Autonoma de Madrid, Campus de Cantoblanco, E-28049, Madrid (Spain)

    2009-06-15

    X-ray micro-computed tomography is an excellent tool to examine the morphology of a sample in a non-destructive way, making its inner structure visible. Nuclear microscopy provides quantitative information about the elemental distribution and concentration. Both can be used as complementary techniques in order to get more information about the samples. Osteoporosis is a disease that deteriorates the bone due to, among other things, a failure in the normal hormonal function. In this project, bones from rats under osteoporosis treatments based on hormonal supplementation, as well as healthy bones and osteoporotic ones without treatment, have been analyzed by both nuclear microscopy and X-ray micro-tomography. Following the results achieved by nuclear microscopy, quantitative concentration and distribution of elements such as Ca and P suggested a change in bone density. In order to image this change of density, the same samples have been analyzed by micro-tomography.

  19. Journal of Applied Biosciences

    African Journals Online (AJOL)

    The Journal of Applied Biosciences provides a forum for scholars and practitioners in all spheres of biological sciences to publish their research findings or theoretical concepts and ideas of a scientific nature. Other websites related to this journal: http://m.elewa.org/Journals/about-jab/ ...

  20. Single vesicle biochips for ultra-miniaturized nanoscale fluidics and single molecule bioscience

    DEFF Research Database (Denmark)

    Christensen, Andreas Lauge; Lohr, Christina; Christensen, Sune M.

    2013-01-01

    , their fabrication via controlled self-assembly, and their characterization using fluorescence microscopy. We also highlight their applications in selected fields such as nanofluidics and single molecule bioscience. Despite their great potential for improved biocompatibility, extreme miniaturization and high...

  1. Nuclear microscopy of fluid inclusions at the CSIRO

    International Nuclear Information System (INIS)

    Ryan, C.; Van Achterbergh, E.; Win, T.T.; McInnes, B.; Cripps, G.; Suter, G.; Liu, W.

    2003-01-01

    Full text: The deep penetration of a MeV energy proton beam and the predictable nature of X-ray production using proton induced X-ray emission (PIXE) make the nuclear microprobe ideally suited to the imaging and analysis of fluid and melt inclusions in minerals. MeV protons interact with a target through electronic interactions with a loss of ∼100 eV per collision. Such small energy loss leads to a smooth and predictable slowing down behaviour with a small energy uncertainty. Furthermore, the small momentum transfers in these collisions result in negligible spreading of the beam (e.g. ∼1 μm at 40 μm depth in quartz). Hence, the proton path can be regarded as linear. The principle mechanisms for proton energy loss, proton-induced ionization, secondary fluorescence and X-ray absorption and detection are understood and well characterized. This enables the integration of expected PIXE X-ray yields along the path of the proton beam and provides the foundation for a standardless microanalytical method. A strength of standardless PIXE analysis enables the approach to be extended to complex problems where the production of standards becomes impractical or unrepresentative of natural samples. One such problem is the study of ore metal transport and ore formation processes using the non-destructive analysis of fluids trapped as fluid inclusions in minerals using a raster-scanned proton probe. In this case, the integration of PIXE X-rays can be confined to the volume of the fluid inclusion in order to calculate the yield of elemental X-rays per ppm of an element. This calculation is illustrated, which shows one volume element of the fluid inclusion excited by the beam and the X-ray path to a detector. The CSIRO-GEMOC Nuclear Microprobe can focus a 3 MeV proton beam into a 1.3 μm beam spot for fluid inclusion analysis and intense beams for mineral imaging at 1.8 μm resolution (Ryan et al., 2001a). Quantitative elemental images are projected using the Dynamic Analysis

  2. Solid-state nuclear-spin quantum computer based on magnetic resonance force microscopy

    International Nuclear Information System (INIS)

    Berman, G. P.; Doolen, G. D.; Hammel, P. C.; Tsifrinovich, V. I.

    2000-01-01

    We propose a nuclear-spin quantum computer based on magnetic resonance force microscopy (MRFM). It is shown that an MRFM single-electron spin measurement provides three essential requirements for quantum computation in solids: (a) preparation of the ground state, (b) one- and two-qubit quantum logic gates, and (c) a measurement of the final state. The proposed quantum computer can operate at temperatures up to 1 K. (c) 2000 The American Physical Society

  3. Bioscience, bioinnovations, and bioethics.

    Science.gov (United States)

    Leisola, Matti

    2007-01-01

    Biosciences and their applications, which we call biotechnology, have affected human society in many ways. Great hopes have been set on future biotechnology. The future depends on three key issues. First, we need good science. Recent developments in biosciences have surprised us in many ways. I shall explain in this article how. Secondly, we need structured innovation systems in order to commercialize our discoveries. Europe is slow in this respect compared to our Japanese and American competitors and may lose in the competition. I shall describe the Finnish innovation chain using the rewarded Otaniemi model as an example of how commercialization can be done in a systematic way. Thirdly, we need norms to guide what to do and where to go. Bioethics is probably the most neglected of the three key issues. With modern biotechnology we are able to do things that should worry every citizen, but the ethical discussion has been largely neglected or the discussion in our pluralistic society is leading nowhere. I shall finally discuss these problems from a historical perspective.

  4. Identification and quantitive analysis of calcium phosphate microparticles in intestinal tissue by nuclear microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Gomez-Morilla, Inmaculada [Advanced Technology Institute, University of Surrey, Guildford GU2 7XH (United Kingdom)]. E-mail: i.gomez-morilla@surrey.ac.uk; Thoree, Vinay [Gastrointestinal Laboratory, Rayne Institute, St. Thomas' Hospital, London SE1 7EH (United Kingdom); Powell, Jonathan J. [MRC Human Nutrition Research, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL (United Kingdom); Kirkby, Karen J. [Advanced Technology Institute, University of Surrey, Guildford GU2 7XH (United Kingdom); Grime, Geoffrey W. [Department of Physics, University of Surrey, GU2 7XH (United Kingdom)

    2006-08-15

    Microscopic particles (0.5-2 {mu}m diameter), rich in calcium and phosphorus, are found in the lumen of the mid-distal gut of all mammals investigated, including humans, and these may play a role in immuno-surveillance and immune regulation of antigens from food and symbiotic bacteria that are contained in the gut. Whether these particles can cross in to tissue of the intestinal mucosa is unclear. If so, characterising their morphology and chemical composition is an important task in elucidating their function. The analysis of calcium phosphate in biological tissues has been approached in several ways including optical microscopy, scanning electron microscopy and, most recently in this work, with nuclear microscopy. In this paper, we describe the use of microPIXE and microRBS to locate these particles and to determine, accurately, the ratio of phosphorus to calcium using the information on sample thickness obtained from RBS to allow the PIXE ratios to be corrected. A commercial sample of hydroxy apatite was used to demonstrate accuracy and precision of the technique. Then, in a pilot study on intestinal tissue of mice, we demonstrated the presence of calcium phosphate microparticles, consistent with confocal microscopy observations, and we identified the average molar P:Ca molar ratio as 1.0. Further work will confirm the exact chemical speciation of these particles and will examine the influence of differing calcium containing diets on the formation of these microparticles.

  5. Differences in Nuclear DNA Organization Between Lymphocytes, Hodgkin and Reed–Sternberg Cells Revealed by Structured Illumination Microscopy

    NARCIS (Netherlands)

    Righolt, C.H.; Guffei, A.; Knecht, H.; Young, I.T.; Stallinga, S.; Van Vliet, L.J.; Mai, S.

    2014-01-01

    Advances in light microscopy have enabled the visualization of DNA in the interphase nucleus with more detail than is visible with conventional light microscopy. The nuclear architecture is assumed to be different in cancer cells compared to normal cells. In this paper we have studied, for the first

  6. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. DALE JAMIESON. Articles written in Journal of Biosciences. Volume 43 Issue 1 March 2018 pp 3-8 Commentary. Liberating primatology · SINDHU RADHAKRISHNA DALE JAMIESON · More Details Abstract Fulltext PDF ...

  7. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Vidita A Vaidya. Articles written in Journal of Biosciences. Volume 25 Issue 2 June 2000 pp 123-124. Clipboard: Stress, depression and hippocampal damage · Vidita A Vaidya · More Details Fulltext PDF ...

  8. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Cover page gallery. Cover page gallery. Journal of Biosciences. Cover page. Journal of Biosciences. Current Issue : Vol. 43, Issue 1. Current Issue Volume 43 | Issue 1. March 2018. Home · Volumes & Issues · Special Issues · Forthcoming Articles · Gallery of Cover Art · Search ...

  9. A new approach to nuclear microscopy: The ion-electron emission microscope

    International Nuclear Information System (INIS)

    Doyle, B.L.; Vizkelethy, G.; Walsh, D.S.; Senftinger, B.; Mellon, M.

    1998-01-01

    A new multidimensional high lateral resolution ion beam analysis technique, Ion-Electron Emission Microscopy or IEEM is described. Using MeV energy ions, IEEM is shown to be capable of Ion Beam Induced Charge Collection (IBICC) measurements in semiconductors. IEEM should also be capable of microscopically and multidimensionally mapping the surface and bulk composition of solids. As such, IIEM has nearly identical capabilities as traditional nuclear microprobe analysis, with the advantage that the ion beam does not have to be focused. The technique is based on determining the position where an individual ion enters the surface of the sample by projection secondary electron emission microscopy. The x-y origination point of a secondary electron, and hence the impact coordinates of the corresponding incident ion, is recorded with a position sensitive detector connected to a standard photoemission electron microscope (PEEM). These signals are then used to establish coincidence with IBICC, atomic, or nuclear reaction induced ion beam analysis signals simultaneously caused by the incident ion

  10. Identification of crystals in Hanford nuclear waste using polarized light microscopy

    International Nuclear Information System (INIS)

    Herting, D.L.

    1984-09-01

    The use of polarized light microscopy for identifying crystals encountered in Rockwell Hanford Operations chemical studies is described. Identifying characteristics and full-color photographs are presented for crystals commonly found in Hanford Site nuclear waste, including sodium nitrate, sodium nitrite, sodium aluminate, sodium phosphate, sodium fluoride, ammonium heptafluorozirconate, sodium sulfate, sodium carbonate, and ammonium nitrate. These characteristics are described in terms of birefringence, extinction position, interference figure, sign of elongation, optic sign, and crystal morphology. Background information on crystal optics is presented so that these traits can be understood by the nonmicroscopist. Detailed operational instructions are given so that the novice microscope user can make the proper adjustments of the instrument to search for and observe the identifying features of the crystals

  11. Observation of nuclear track in organic material by atomic force microscopy in real time during etching

    CERN Document Server

    Palmino, F; Labrune, J C

    1999-01-01

    The developments of Atomic Force Microscopy (AFM) allow to investigated solid surfaces with a nanometer scale. These techniques are useful methods allowing direct observation of surface morphologies. Particularly in the nuclear track fields, they offer a new tool to give many new informations on track formation. In this paper we present the preliminary results of a new use of this technique to characterize continuously the formation of the revealed track in a cellulose nitrate detector (LR115) after an alpha particle irradiation. For that, a specific cell has been used to observe, by nano-observations, the evolution of track shapes simultaneously with chemical treatment. Thus, the track shape evolution has been studied; visualizing the evolution of the tracks in real time, in situ during the chemical etching process.

  12. Nuclear microscopy as a tool in TiO2 nanoparticles bioaccumulation studies in aquatic species

    International Nuclear Information System (INIS)

    Pinheiro, Teresa; Moita, Liliana; Silva, Luís; Mendonça, Elsa; Picado, Ana

    2013-01-01

    Engineered Titanium nanoparticles are used for a wide range of applications from coatings, sunscreen cosmetic additives to solar cells or water treatment agents. Inevitably environmental exposure can be expected and data on the ecotoxicological evaluation of nanoparticles are still scarce. The potential effects of nanoparticles of titanium dioxide (TiO 2 ) on two model organisms, the water flea, Daphnia magna and the duckweed Lemna minor, were examined in semichronic toxicity tests. Daphnia and Lemna were exposed to TiO 2 nanoparticles (average particle size value of 28 ± 11 nm (n = 42); concentration range, 1.4–25 mg/L) by dietary route and growth in medium containing the nanoparticles of TiO 2 , respectively. Both morphology and microdistribution of Ti in the individuals were examined by nuclear microscopy techniques. A significant amount of TiO 2 was found accumulated in Daphnia exposed to nanoparticles. Nuclear microscopy imaging revealed that Ti was localized only in the digestive tract of the Daphnia, which displayed difficulty in eliminating the nanoparticles from their body. Daphnia showed higher mortality when exposed to higher concentrations of TiO 2 (>10 mg/L). The exposure to TiO 2 nanoparticles above 25 mg/L caused morphological alterations in Lemna. The roots became stiff and fronds colorless. The Ti mapping of cross-sections of roots and fronds showed that Ti was mainly deposited in the epidermis of the fronds and roots, with minor internalization. In summary, exposure of aquatic organisms to TiO 2 nanoparticles may alter the physiology of these organisms at individual and population levels, posing risks to aquatic ecosystems

  13. Nuclear microscopy as a tool in TiO2 nanoparticles bioaccumulation studies in aquatic species

    Science.gov (United States)

    Pinheiro, Teresa; Moita, Liliana; Silva, Luís; Mendonça, Elsa; Picado, Ana

    2013-07-01

    Engineered Titanium nanoparticles are used for a wide range of applications from coatings, sunscreen cosmetic additives to solar cells or water treatment agents. Inevitably environmental exposure can be expected and data on the ecotoxicological evaluation of nanoparticles are still scarce. The potential effects of nanoparticles of titanium dioxide (TiO2) on two model organisms, the water flea, Daphnia magna and the duckweed Lemna minor, were examined in semichronic toxicity tests. Daphnia and Lemna were exposed to TiO2 nanoparticles (average particle size value of 28 ± 11 nm (n = 42); concentration range, 1.4-25 mg/L) by dietary route and growth in medium containing the nanoparticles of TiO2, respectively. Both morphology and microdistribution of Ti in the individuals were examined by nuclear microscopy techniques. A significant amount of TiO2 was found accumulated in Daphnia exposed to nanoparticles. Nuclear microscopy imaging revealed that Ti was localized only in the digestive tract of the Daphnia, which displayed difficulty in eliminating the nanoparticles from their body. Daphnia showed higher mortality when exposed to higher concentrations of TiO2 (>10 mg/L). The exposure to TiO2 nanoparticles above 25 mg/L caused morphological alterations in Lemna. The roots became stiff and fronds colorless. The Ti mapping of cross-sections of roots and fronds showed that Ti was mainly deposited in the epidermis of the fronds and roots, with minor internalization. In summary, exposure of aquatic organisms to TiO2 nanoparticles may alter the physiology of these organisms at individual and population levels, posing risks to aquatic ecosystems.

  14. Environmental Biosciences Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2007-01-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the DOE. Plans for restructuring the performance schedule of the trichloroethylene projects have been submitted to the department. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this

  15. In Situ Characterization of Nuclear Energy Materials by Synchrotron Radiation and Electron Microscopy

    International Nuclear Information System (INIS)

    Li Meimei

    2015-01-01

    This paper presents the applications of in situ characterization techniques, including transmission electron microscopy (TEM) with in situ ion irradiation and high energy X ray diffraction with simultaneous thermal-mechanical loading, in the study of structural materials in advanced nuclear reactors. A good example cases is given here: a novel experiment of TEM with in situ ion irradiation of Mo thin films by 1 MeV Kr ion irradiation that was designed explicitly to improve and validate a computer model. A rate theory based cluster dynamic model was developed to model the ion irradiation induced damage in the thin film with temporal and spatial dependence of defect distribution. Experimental data were compared in detail with modelling results under exactly matched irradiation conditions. The interplay between experiments and modelling allowed an improved understanding of the physical process during irradiation and the development of an accurate physical model. Another area discussed is that of high energy X ray diffraction measurements of bulk materials under thermal/thermal-mechanical loading. This type of in situ characterization provides information on phase transformation and stability and the effect of microstructural changes on mechanical properties, essential to the development of predictive models of materials’ long term performance in nuclear reactor environments. Currently, an in situ radioactive materials probe is being developed for measuring irradiated materials under temperature and loading conditions. (author)

  16. A nuclear microscopy study of trace elements Ca, Fe, Zn and Cu in atherosclerosis

    Energy Technology Data Exchange (ETDEWEB)

    Watt, F. [Centre for Ion Beam Applications, Department of Physics, National University of Singapore, Singapore 117542 (Singapore)]. E-mail: phywattf@nus.edu.sg; Rajendran, R. [Centre for Ion Beam Applications, Department of Physics, National University of Singapore, Singapore 117542 (Singapore); Department of Biochemistry, National University of Singapore, Singapore 117542 (Singapore); Ren, M.Q. [Centre for Ion Beam Applications, Department of Physics, National University of Singapore, Singapore 117542 (Singapore); Department of Biochemistry, National University of Singapore, Singapore 117542 (Singapore); Tan, B.K.H. [Department of Pharmacology, National University of Singapore, Singapore 117542 (Singapore); Halliwell, B. [Department of Biochemistry, National University of Singapore, Singapore 117542 (Singapore)

    2006-08-15

    Quantitative mapping of trace elements Ca, Fe, Zn and Cu can be achieved in biological tissue using a nuclear microprobe. Presented here is a brief review of the work we have carried out in the last decade using the nuclear microscope to try and elucidate the role of trace elements Fe, Zn, Cu and Ca in induced atherosclerosis in New Zealand White rabbits fed on a 1% cholesterol diet. The lesions were studied using nuclear microscopy, incorporating a combination of ion beam techniques: particle induced X-ray emission (PIXE), Rutherford backscattering spectrometry (RBS) and scanning transmission ion microscopy (STIM). Iron is present in early lesions at concentrations around seven times higher than the artery wall. Measurements of localized lesion iron concentrations were observed to be highly correlated with the depth of the lesion in the artery wall for each individual animal, implying that local elevated concentrations may provide an accelerated process of atherosclerosis in specific regions of the artery. When the rabbits were kept mildly anaemic, thereby reducing iron levels in the lesion, the progression of the disease was significantly slowed. Iron chelation using desferal showed that early treatment (three weeks into the high fat diet) for relatively long periods (nine weeks) significantly retarded the progression of the disease. Zinc is depleted in the lesion and is also observed to be anti-correlated with local lesion development and feeding the rabbits on a high fat diet with zinc supplements inhibited lesion development, although since no significant increase in lesion zinc levels was measured, this anti-atherosclerotic effect may be indirect. Copper, measured at low levels ({approx}3 ppm) in the early lesion, is also depleted compared to the artery wall, suggesting that it is not a major factor in atherogenesis. Calcium is also depleted in early lesions, although at a later stage mineral deposition (hydroxyapatite) is observed to take place in the lesion

  17. Changes of the elemental distributions in marine diatoms as a reporter of sample preparation artefacts. A nuclear microscopy application

    Energy Technology Data Exchange (ETDEWEB)

    Godinho, R.M. [Instituto de Bioengenharia e Biociências, Instituto Superior Técnico, Universidade de Lisboa, Lisboa (Portugal); Instituto Português do Mar e da Atmosfera, Lisboa (Portugal); Centro Interdisciplinar de Investigação Marinha e Ambiental, Universidade do Porto, Porto (Portugal); Cabrita, M.T. [Instituto Português do Mar e da Atmosfera, Lisboa (Portugal); Centro Interdisciplinar de Investigação Marinha e Ambiental, Universidade do Porto, Porto (Portugal); Alves, L.C. [Centro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, Sacavém (Portugal); Pinheiro, T., E-mail: murmur@ctn.ist.utl.pt [Instituto de Bioengenharia e Biociências, Instituto Superior Técnico, Universidade de Lisboa, Lisboa (Portugal)

    2015-04-01

    Studies of the elemental composition of whole marine diatoms cells have high interest as they constitute a direct measurement of environmental changes, and allow anticipating consequences of anthropogenic alterations to organisms, ecosystems and global marine geochemical cycles. Nuclear microscopy is a powerful tool allowing direct measurement of whole cells giving qualitative imaging of distribution, and quantitative determination of intracellular concentration. Major obstacles to the analysis of marine microalgae are high medium salinity and the recurrent presence of extracellular exudates produced by algae to maintain colonies in natural media and in vitro. The objective of this paper was to optimize the methodology of sample preparation of marine unicellular algae for elemental analysis with nuclear microscopy, allowing further studies on cellular response to metals. Primary cultures of Coscinodiscus wailesii maintained in vitro were used to optimize protocols for elemental analysis with nuclear microscopy techniques. Adequate cell preparation procedures to isolate the cells from media components and exudates were established. The use of chemical agents proved to be inappropriate for elemental determination and for intracellular morphological analysis. The assessment of morphology and elemental partitioning in cell compartments obtained with nuclear microscopy techniques enabled to infer their function in natural environment and imbalances in exposure condition. Exposure to metal affected C. wailesii morphology and internal elemental distribution.

  18. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Seyed E Hasnain. Articles written in Journal of Biosciences. Volume 26 Issue 3 September 2001 pp 333-339 Articles. Specificity of drug transport mediated by CaMDR1: a major facilitator of Candida albicans · Avmeet Kohli Vinita Gupta Shankarling Krishnamurthy Seyed E Hasnain ...

  19. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Forum Kayastha. Articles written in Journal of Biosciences. Volume 40 Issue 2 June 2015 pp 313-324 Articles. Andrographolide suppresses epithelial mesenchymal transition by inhibition of MAPK signalling pathway in lens epithelial cells · Forum Kayastha Kaid Johar Devarshi ...

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    Home; Journals; Journal of Biosciences. M T Tanuja. Articles written in Journal of Biosciences. Volume 26 Issue 1 March 2001 pp 71-76 Articles. Incipient sexual isolation in the nasuta-albomicans complex of Drosophila: No-choice experiments · M T Tanuja N B Ramachandra H A Ranganath · More Details Abstract Fulltext ...

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    Home; Journals; Journal of Biosciences. G Keller. Articles written in Journal of Biosciences. Volume 34 Issue 5 November 2009 pp 709-728 Articles. Deccan volcanism, the KT mass extinction and dinosaurs · G Keller A Sahni S Bajpai · More Details Abstract Fulltext PDF. Recent advances in Deccan volcanic studies indicate ...

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  11. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Utpal Tatu. Articles written in Journal of Biosciences. Volume 30 Issue 5 December 2005 pp 567-571. Commentary: Whither genome research: Of man, mosquito and malaria · Utpal Tatu Samta Jain P Padma Priya · More Details Fulltext PDF. Volume 32 Issue 3 April 2007 pp ...

  12. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. RAM A PANDEY. Articles written in Journal of Biosciences. Volume 43 Issue 1 March 2018 pp 105-115 Article. Root transcripts associated with arsenic accumulation in hyperaccumulator Pteris vittata · RASIKA M POTDUKHE PRIYANKA BEDI BIJAYA K SARANGI RAM A PANDEY ...

  13. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. R S Policegoudra. Articles written in Journal of Biosciences. Volume 35 Issue 2 June 2010 pp 231-240 Articles. Antimicrobial, antioxidant, cytotoxicity and platelet aggregation inhibitory activity of a novel molecule isolated and characterized from mango ginger (Curcuma amada Roxb ...

  14. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. AMOTZ ZAHAVI. Articles written in Journal of Biosciences. Volume 43 Issue 1 March 2018 pp 49-58 Article. An individual-level selection model for the apparent altruism exhibited by cellular slime moulds · AMOTZ ZAHAVI KEITH D HARRIS VIDYANAND NANJUNDIAH · More Details ...

  15. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Durai Sundar. Articles written in Journal of Biosciences. Volume 37 Issue 3 July 2012 pp 483-491 Articles. Prediction of DNA-binding specificity in zinc finger proteins · Sumedha Roy Shayoni Dutta Kanika Khanna Shruti Singla Durai Sundar · More Details Abstract Fulltext PDF.

  16. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. PRATAP C MALI. Articles written in Journal of Biosciences. Volume 43 Issue 1 March 2018 pp 149-154 Mini-Review. Triacylglycerol: nourishing molecule in endurance of Mycobacterium tuberculosis · PRATAP C MALI LAXMAN S MEENA · More Details Abstract Fulltext PDF.

  17. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Milena Radakovic. Articles written in Journal of Biosciences. Volume 38 Issue 1 March 2013 pp 53-62 Articles. Evaluation of the DNA damaging effects of amitraz on human lymphocytes in the Comet assay · Milena Radakovic Jevrosima Stevanovic Ninoslav Djelic Nada Lakic Jelena ...

  18. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Subhash C Lakhotia. Articles written in Journal of Biosciences. Volume 29 Issue 3 September 2004 pp 219-224. Commentary: Epigenetics of heterochromatin · Subhash C Lakhotia · More Details Fulltext PDF. Volume 32 Issue 3 April 2007 pp 429-431. Foreword · Subhash C ...

  19. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. SUMITRA NAIN. Articles written in Journal of Biosciences. Volume 42 Issue 3 September 2017 pp 481-490 Article. Promoter polymorphism MMP-1 (-1607 2G/1G) and MMP-3 (-1612 5A/6A) in development of HAND and modulation of pathogenesis of HAND · HARI OM SINGH ...

  20. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. BETANIA B COTA. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 657-664 Article. In vitro leishmanicidal, antibacterial and antitumour potential of anhydrocochlioquinone A obtained from the fungus Cochliobolus sp. FERNANDA F CAMPOS JONAS ...

  1. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. M Vijayan. Articles written in Journal of Biosciences. Volume 32 Issue 6 September 2007 pp 1059-1066 Perspectives. Peanut lectin crystallography and macromolecular structural studies in India · M Vijayan · More Details Fulltext PDF. Volume 32 Issue 6 September 2007 pp ...

  2. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. VIDYANAND NANJUNDIAH. Articles written in Journal of Biosciences. Volume 25 Issue 1 March .... An individual-level selection model for the apparent altruism exhibited by cellular slime moulds · AMOTZ ZAHAVI KEITH D HARRIS VIDYANAND NANJUNDIAH · More Details Abstract ...

  3. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. AA SULTAN. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 531-535 Brief communication. Antifolate drug resistance: Novel mutations and haplotype distribution in dhps and dhfr from Northeast India · NP SARMAH K SARMA DR BHATTACHARYYA ...

  4. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Satya Keerthi Kota. Articles written in Journal of Biosciences. Volume 30 Issue 3 June 2005 pp 329-337 Articles. Cloning and characterization of mouse cullin4B/E3 ubiquitin ligase · Rachana Tripathi K Seetharama Satya Keerthi Kota Usha K Srinivas · More Details Abstract Fulltext ...

  5. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. LI-MIN FENG. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 547-554 Article. Thymoquinone induces cytotoxicity and reprogramming of EMT in gastric cancer cells by targeting PI3K/Akt/mTOR pathway · LI-MIN FENG XUE-FENG WANG QING-XIAN ...

  6. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. P Chauhan. Articles written in Journal of Biosciences. Volume 34 Issue 5 November 2009 pp 729-747 Articles. India at the cross-roads of human evolution · R Patnaik P Chauhan · More Details Abstract Fulltext PDF. The Indian palaeoanthropological record, although patchy at the ...

  7. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Wulong Liang. Articles written in Journal of Biosciences. Volume 40 Issue 1 March 2015 pp 79-90 Articles. Co-expression of the C-terminal domain of Yersinia enterocolitica invasin enhances the efficacy of classical swine-fever-vectored vaccine based on human adenovirus.

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    Home; Journals; Journal of Biosciences. Najma Zaheer Baquer. Articles written in Journal of Biosciences. Volume 30 Issue 4 September 2005 pp 483-490 Articles. Amelioration of altered antioxidant status and membrane linked functions by vanadium and Trigonella in alloxan diabetic rat brains · Mohammad Rizwan ...

  9. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Najma Z Baquer. Articles written in Journal of Biosciences. Volume 28 Issue 2 March 2003 pp 215-221 Articles. Regulation of glucose utilization and lipogenesis in adipose tissue of diabetic and fat fed animals: Effects of insulin and manganese · Najma Z Baquer M Sinclair S Kunjara ...

  10. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Julio Reyes Leyva. Articles written in Journal of Biosciences. Volume 37 Issue 6 December 2012 pp 999-1004 Articles. Sialyl Lewis x expression in cervical scrapes of premalignant lesions · Noé Velázquez-Márquez Gerardo Santos López Lucio Jiménez Aranda Julio Reyes Leyva ...

  11. Journal of Biosciences | Indian Academy of Sciences

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  12. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Basuthkar J Rao. Articles written in Journal of Biosciences. Volume 26 Issue 5 December 2001 pp 583-594 Articles. Local repeat sequence organization of an intergenic spacer in the chloroplast genome of Chlamydomonas reinhardtii leads to DNA expansion and sequence ...

  13. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Aparup Das. Articles written in Journal of Biosciences. Volume 39 Issue 4 September 2014 pp 727-738 Review. Does malaria epidemiology project Cameroon as `Africa in miniature'? · Huguette Gaelle Ngassa Mbenda Gauri Awasthi Poonam K Singh Inocent Gouado Aparup Das.

  14. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Vindhya Mohindra. Articles written in Journal of Biosciences. Volume 38 Issue 2 June 2013 pp 373-383 Articles. Physiological responses to acute experimental hypoxia in the air-breathing Indian catfish, Clarias batrachus (Linnaeus, 1758) · Ratnesh Kumar Tripathi Vindhya Mohindra ...

  15. Journal of Biosciences | Indian Academy of Sciences

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  16. Journal of Biosciences | Indian Academy of Sciences

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  17. Journal of Biosciences | Indian Academy of Sciences

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  18. Journal of Biosciences | Indian Academy of Sciences

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  19. Journal of Biosciences | Indian Academy of Sciences

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  20. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. G R Kulkarni. Articles written in Journal of Biosciences. Volume 29 Issue 3 September 2004 pp 349-353 Articles. Extracellular electrical activity from the photoreceptors of midge · A A Babrekar G R Kulkarni B B Nath P B Vidyasagar · More Details Abstract Fulltext PDF. The ontogeny ...

  1. Journal of Biosciences | Indian Academy of Sciences

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  2. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. T J Pandian. Articles written in Journal of Biosciences. Volume 25 Issue 1 March 2000 pp 41-45 Articles. Cloning of partial putative gonadotropin hormone receptor sequence from fish · G Kumaresan T Venugopal A Vikas T J Pandian S M Athavan · More Details Abstract Fulltext PDF.

  3. Journal of Biosciences | Indian Academy of Sciences

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  5. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Moushami Mallik. Articles written in Journal of Biosciences. Volume 32 Issue 3 April 2007 pp 595-610 Articles. Heat shock genes – integrating cell survival and death · Richa Arya Moushami Mallik Subhash C Lakhotia · More Details Abstract Fulltext PDF. Heat shock induced gene ...

  6. Journal of Biosciences | Indian Academy of Sciences

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  7. Journal of Biosciences | Indian Academy of Sciences

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  8. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Mihaly Mezei. Articles written in Journal of Biosciences. Volume 37 Issue 3 July 2012 pp 379-397 Articles. The ABCs of molecular dynamics simulations on B-DNA, circa 2012 · David L Beveridge Thomas E Cheatham III Mihaly Mezei · More Details Abstract Fulltext PDF. This article ...

  9. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. A Sahni. Articles written in Journal of Biosciences. Volume 34 Issue 5 November 2009 pp 673-686 Articles. The origin and early evolution of whales: macroevolution documented on the Indian Subcontinent · S Bajpai J G M Thewissen A Sahni · More Details Abstract Fulltext PDF.

  10. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Gautam Bhattacharjee. Articles written in Journal of Biosciences. Volume 27 Issue 3 June 2002 pp 283-294 Articles. Cocoon production, morphology, hatching pattern and fecundity in seven tropical earthworm species – a laboratory-based investigation · Gautam Bhattacharjee P S ...

  11. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. NP SARMAH. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 531-535 Brief communication. Antifolate drug resistance: Novel mutations and haplotype distribution in dhps and dhfr from Northeast India · NP SARMAH K SARMA DR ...

  12. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Prakash Kulkarni. Articles written in Journal of Biosciences. Volume 39 Issue 2 April 2014 pp 281-302 Articles. Competing views on cancer · Carlos Sonnenschein Ana M Soto Annapoorni Rangarajan Prakash Kulkarni · More Details Abstract Fulltext PDF. Despite intense research ...

  13. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Ana M soto. Articles written in Journal of Biosciences. Volume 30 Issue 1 February 2005 pp 103-118. Emergentism as a default: Cancer as a problem of tissue organization · Ana M soto Carlos Sonnenschein · More Details Abstract Fulltext PDF. During the last fifty years the dominant ...

  14. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Piyali Ganguli. Articles written in Journal of Biosciences. Volume 40 Issue 4 October 2015 pp 769-789 Articles. Temporal protein expression pattern in intracellular signalling cascade during T-cell activation: A computational study · Piyali Ganguli Saikat Chowdhury Rupa Bhowmick ...

  15. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

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  16. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. VINOD KUMAR. Articles written in Journal of Biosciences. Volume 40 Issue 2 June 2015 pp 399-406 Articles. Mammalian gastrointestinal parasites in rainforest remnants of Anamalai Hills, Western Ghats, India · Debapriyo Chakraborty Shaik Hussain D Mahendar Reddy Sachin ...

  17. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. X Huang. Articles written in Journal of Biosciences. Volume 28 Issue 1 February 2003 pp 95-100. Induction of interleukin-6 by coal containing bioavailable iron is through both hydroxyl radical and ferryl species · Q Zhang X Huang · More Details Abstract Fulltext PDF. Coal mining ...

  18. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Arnab Ganguli. Articles written in Journal of Biosciences. Volume 29 Issue 4 December 2004 pp 471-487. Heat stress response in plants: a complex game with chaperones and more than twenty heat stress transcription factors · Sanjeev Kumar Baniwal Kapil Bharti Kwan Yu Chan ...

  19. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Lida Zhang. Articles written in Journal of Biosciences. Volume 34 Issue 1 March 2009 pp 71-83 Articles. Molecular evolution of the E8 promoter in tomato and some of its relative wild species · Lingxia Zhao Liya Lu Lida Zhang Aoxue Wang Ning Wang Zhuobin Liang Xiaowen Lu ...

  20. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Gregor Durstewitz. Articles written in Journal of Biosciences. Volume 37 Issue 5 November 2012 pp 821-828 Articles. Large SNP arrays for genotyping in crop plants · Martin W Ganal Andreas Polley Eva-Maria Graner Joerg Plieske Ralf Wieseke Hartmut Luerssen Gregor Durstewitz.

  1. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Carina Goswami. Articles written in Journal of Biosciences. Volume 29 Issue 2 June 2004 pp 179-187 Articles. Effects of anisotonicity on pentose-phosphate pathway, oxidized glutathione release and t-butylhydroperoxide-induced oxidative stress in the perfused liver of air-breathing ...

  2. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. HARINDER SINGH. Articles written in Journal of Biosciences. Volume 35 Issue 3 September 2010 pp 427-434 Articles. Unusual radioresistance of nitrogen-fixing cultures of Anabaena strains · Harinder Singh Tonina Fernandes Shree Kumar Apte · More Details Abstract Fulltext PDF.

  3. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. K Ilango. Articles written in Journal of Biosciences. Volume 25 Issue 2 June 2000 pp 163-172 Articles. Morphological characteristics of the antennal flagellum and its sensilla chaetica with character displacement in the sandfly Phlebotomus argentipes Annandale and Brunetti sensu ...

  4. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Hawk-Bin Kwon. Articles written in Journal of Biosciences. Volume 30 Issue 5 December 2005 pp 657-667 Articles. Expression profiles of hot pepper (Capsicum annuum) genes under cold stress conditions · Eul-Won Hwang Kyung-A Kim Soo-Chul Park Mi-Jeong Jeong Myung-Ok ...

  5. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Bhagyashri A Shanbhag. Articles written in Journal of Biosciences. Volume 29 Issue 1 March 2004 pp 105-110 Articles. Factors influencing offspring traits in the oviparous multi-clutched lizard, Calotes versicolor (Agamidae) · Rajkumar S Radder Bhagyashri A Shanbhag.

  6. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Pankaj Kumar. Articles written in Journal of Biosciences. Volume 32 Issue 1 January 2007 pp 3-15 Articles. Simple sequence repeats in mycobacterial genomes · Vattipally B Sreenu Pankaj Kumar Javaregowda Nagaraju Hampapathalu A Nagarajaram · More Details Abstract Fulltext ...

  7. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Visenuo Aiko. Articles written in Journal of Biosciences. Volume 40 Issue 5 December 2015 pp 943-954 Review. Occurrence, detection and detoxification of mycotoxins · Visenuo Aiko Alka Mehta · More Details Abstract Fulltext PDF. Mycotoxins have been identified as important ...

  8. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. R Usha. Articles written in Journal of Biosciences. Volume 28 Issue 5 September 2003 pp 589-595 Articles. High genetic diversity in the coat protein and 3' untranslated regions among geographical isolates of Cardamom mosaic virus from south India · T Jacob T Jebasingh M N ...

  9. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Odir A Dellagostin. Articles written in Journal of Biosciences. Volume 33 Issue 3 September 2008 pp 355-363 Articles. Purification and molecular cloning of a new galactose-specific lectin from Bauhinia variegata seeds · Luciano S Pinto Celso S Nagano Taianá M Oliveira Tales R ...

  10. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. George Thomas. Articles written in Journal of Biosciences. Volume 33 Issue 1 March 2008 pp 81-90 Articles. Defence transcriptome profiling of Zingiber zerumbet (L.) Smith by mRNA differential display · P G Kavitha George Thomas · More Details Abstract Fulltext PDF. Soft rot is a ...

  11. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Lorena Carro. Articles written in Journal of Biosciences. Volume 38 Issue 4 November 2013 pp 685-693 Articles. Micromonospora is a normal occupant of actinorhizal nodules · Lorena Carro Petar Pujic Martha E Trujillo Phillipe Normand · More Details Abstract Fulltext PDF.

  12. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Subrata Basu Ray. Articles written in Journal of Biosciences. Volume 26 Issue 5 December 2001 pp 555-559. Commentary: The enigma of morphine tolerance: recent insights · Subrata Basu Ray Shashi Wadhwa · More Details Fulltext PDF. Volume 29 Issue 1 March 2004 pp 51-56 ...

  13. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. S A Ranade. Articles written in Journal of Biosciences. Volume 25 Issue 3 September 2000 pp 291-299 Review articles. Role of polyamines and ethylene as modulators of plant senescence · S Pandey S A Ranade P K Nagar Nikhil Kumar · More Details Abstract Fulltext PDF.

  14. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Anil K Gupta. Articles written in Journal of Biosciences. Volume 27 Issue 7 December 2002 pp 703-714 Review Article. Applications of inulin and oligofructose in health and nutrition · Narinder Kaur Anil K Gupta · More Details Abstract Fulltext PDF. Inulin and oligofructose belong to a ...

  15. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. LAXMAN S MEENA. Articles written in Journal of Biosciences. Volume 43 Issue 1 March 2018 pp 149-154 Mini-Review. Triacylglycerol: nourishing molecule in endurance of Mycobacterium tuberculosis · PRATAP C MALI LAXMAN S MEENA · More Details Abstract Fulltext PDF.

  16. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Carlos Sonnenschein. Articles written in Journal of Biosciences. Volume 30 Issue 1 February 2005 pp 103-118. Emergentism as a default: Cancer as a problem of tissue organization · Ana M soto Carlos Sonnenschein · More Details Abstract Fulltext PDF. During the last fifty years the ...

  17. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Franck Molina. Articles written in Journal of Biosciences. Volume 32 Issue 1 January 2007 pp 145-155 Articles. Formal TCA cycle description based on elementary actions · Pierre Mazière Nicolas Parisey Marie Beurton-Aimar Franck Molina · More Details Abstract Fulltext PDF.

  18. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. P Dayanandan. Articles written in Journal of Biosciences. Volume 28 Issue 4 June 2003 pp 455-469 Articles. Structural and histochemical studies on grain-filling in the caryopsis of rice (Oryza sativa L.) S Krishnan P Dayanandan · More Details Abstract Fulltext PDF. The endosperm ...

  19. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Carissa Reason. Articles written in Journal of Biosciences. Volume 40 Issue 2 June 2015 pp 389-398 Articles. Declines of seagrasses in a tropical harbour, North Queensland, Australia, are not the result of a single event · Skye McKenna Jessie Jarvis Tonia Sankey Carissa Reason ...

  20. Journal of Biosciences | Indian Academy of Sciences

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  1. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. DONGHUI LIU. Articles written in Journal of Biosciences. Volume 42 Issue 3 September 2017 pp 417-425 Article. Targeting cleavage and polyadenylation specific factor 1 via shRNA inhibits cell proliferation in human ovarian cancer · BEIGUANG ZHANG YING LIU DONGHUI LIU LEI ...

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    Home; Journals; Journal of Biosciences. Guiyang Liu. Articles written in Journal of Biosciences. Volume 40 Issue 1 March 2015 pp 7-12 Brief communication. Lack of IL-6 increases blood–brain barrier permeability in fungal meningitis · Xiang Li Guiyang Liu Jianli Ma Liang Zhou Qingzhe Zhang Lei Gao · More Details ...

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    Home; Journals; Journal of Biosciences. R K Kale. Articles written in Journal of Biosciences. Volume 29 Issue 1 March 2004 pp 111-117 Articles. Adaptive response and split-dose effect of radiation on the survival of mice · Ashu Bhan Tiku R K Kale · More Details Abstract Fulltext PDF. Although the importance of ...

  4. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Naveen Kumar Nair. Articles written in Journal of Biosciences. Volume 37 Issue 2 June 2012 pp 301-312 Review. Nucleic acids in circulation: Are they harmful to the host? Indraneel Mittra Naveen Kumar Nair Pradyumna Kumar Mishra · More Details Abstract Fulltext PDF. It has been ...

  5. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Veeraputhiran Subbiah. Articles written in Journal of Biosciences. Volume 33 Issue 2 June 2008 pp 185-193 Articles. Identification of a root-specific glycosyltransferase from Arabidopsis and characterization of its promoter · Virupapuram Vijaybhaskar Veeraputhiran Subbiah Jagreet ...

  6. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. GEOFFREY BODENHAUSEN. Articles written in Journal of Biosciences. Volume 38 Issue 2 June 2013 pp 189-199. Commentary: On toxic effects of scientific journals · Antoinette Molinié Geoffrey Bodenhausen · More Details Abstract Fulltext PDF. The advent of online publishing ...

  7. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. ABDUR RAHAMAN. Articles written in Journal of Biosciences. Volume 42 Issue 2 June 2017 pp 333-344 Review. Regulation of dynamin family proteins by post-translational modifications · USHA P KAR HIMANI DEY ABDUR RAHAMAN · More Details Abstract Fulltext PDF. Dynamin ...

  8. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Shweta Dubey. Articles written in Journal of Biosciences. Volume 31 Issue 5 December 2006 pp 497-501. Clipboard: Putting T cells to sleep: a new paradigm for immune evasion by persistent viruses · Shweta Dubey Shahid Jameel · More Details Fulltext PDF ...

  9. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. C SUDHEER KUMAR. Articles written in Journal of Biosciences. Volume 42 Issue 3 September 2017 pp 469-479 Article. Modulation of chaperone-like and membranolytic activities of major horse seminal plasma protein HSP-1/2 by L-carnitine · C SUDHEER KUMAR MUSTI J ...

  10. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Enrique Meléndez-Hevia. Articles written in Journal of Biosciences. Volume 33 Issue 5 December 2008 pp 771-780 Articles. Branch-point stoichiometry can generate weak links in metabolism: the case of glycine biosynthesis · Enrique Meléndez-Hevia Patricia D E Paz-Lugo.

  11. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Srinivasan. Articles written in Journal of Biosciences. Volume 27 Issue 1 February 2002 pp 15-25. Comparative genomics using data mining tools · Tannistha Nandi Chandrika B-Rao Srinivasan Ramachandran · More Details Abstract Fulltext PDF. We have analysed the genomes of ...

  12. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Sanghamitra Bandyopadhyay. Articles written in Journal of Biosciences. Volume 32 Issue 5 August 2007 pp 1019-1025 Articles. Gene ordering in partitive clustering using microarray expressions · Shubhra Sankar Ray Sanghamitra Bandyopadhyay Sankar K Pal · More Details ...

  13. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. G V R Prasad. Articles written in Journal of Biosciences. Volume 34 Issue 5 November 2009 pp 649-659 Articles. Divergence time estimates of mammals from molecular clocks and fossils: Relevance of new fossil finds from India · G V R Prasad · More Details Abstract Fulltext PDF.

  14. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. A Adaikala Koteswari. Articles written in Journal of Biosciences. Volume 28 Issue 6 December 2003 pp 715-721 Articles. Curcumin-induced inhibition of cellular reactive oxygen species generation: Novel therapeutic implications · M Balasubramanyam A Adaikala Koteswari R ...

  15. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. LOCHNER. Articles written in Journal of Biosciences. Volume 43 Issue 1 March 2018 pp 59-74 Article. Thalassiosira mala italic> (Bacillariophyta), a potentially harmful, marine diatom from Chilka Lake and other coastal localities of Odisha, India: Nomenclature, frustule morphology ...

  16. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Heinrich Reichert. Articles written in Journal of Biosciences. Volume 39 Issue 4 September 2014 pp 595-603 Articles. Insights into brain development and disease from neurogenetic analyses in Drosophila melanogaster · Heinrich Reichert · More Details Abstract Fulltext PDF.

  17. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Rajiv K Saxena. Articles written in Journal of Biosciences. Volume 25 Issue 1 March 2000 pp 3-5. Clipboard: Should erythrocyte destruction in vivo be through phagocytosis alone? Rajiv K Saxena · More Details Fulltext PDF. Volume 27 Issue 2 March 2002 pp 143-153 Articles.

  18. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Isaac Salazar-Ciudad. Articles written in Journal of Biosciences. Volume 34 Issue 4 October 2009 pp 573-587 Articles. Looking at the origin of phenotypic variation from pattern formation gene networks · Isaac Salazar-Ciudad · More Details Abstract Fulltext PDF. This article critically ...

  19. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. JANA ALONSO. Articles written in Journal of Biosciences. Volume 41 Issue 4 December 2016 pp 643-658 ARTICLE. Metabolic alterations derived from absence of Two-Pore Channel 1 at cardiac level · VANESSA GARCÍA-RÚA SANDRA FEIJÓO-BANDÍN MARÍA GARCÍA-VENCE ...

  20. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. MUNIASAMY NEERATHILINGAM. Articles written in Journal of Biosciences. Volume 41 Issue 3 September 2016 pp 535-561 Review. Application of aptamers in diagnostics, drug-delivery and imaging · CHETAN CHANDOLA SHEETAL KALME MARCO G CASTELEIJN ARTO URTTI ...

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    Home; Journals; Journal of Biosciences. Niranjan Mishra. Articles written in Journal of Biosciences. Volume 35 Issue 1 March 2010 pp 79-86. Evidence of a humoral immune response against the prokaryotic expressed N-terminal autoprotease (N) protein of bovine viral diarrhoea virus · Niranjan Mishra Katherukamem ...

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    Home; Journals; Journal of Biosciences. Sindhu Radhakrishna. Articles written in Journal of Biosciences. Volume 36 Issue 5 December 2011 pp 749-753. Commentary: Less than wild? Commensal primates and wildlife conservation · Sindhu Radhakrishna Anindya Sinha · More Details Fulltext PDF. Volume 43 Issue 1 ...

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    Home; Journals; Journal of Biosciences. B V Shyamala. Articles written in Journal of Biosciences. Volume 38 Issue 3 September 2013 pp 455-460 Brief communication. Male- and female-specific variants of doublesex gene products have different roles to play towards regulation of Sex combs reduced expression and sex ...

  4. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Vandana Saxena. Articles written in Journal of Biosciences. Volume 33 Issue 4 November 2008 pp 505-514. Preventive strategies for frequent outbreaks of Japanese encephalitis in Northern India · Vandana Saxena Tapan N Dhole · More Details Abstract Fulltext PDF. Japanese ...

  5. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Indraneel Mittra. Articles written in Journal of Biosciences. Volume 37 Issue 2 June 2012 pp 301-312 Review. Nucleic acids in circulation: Are they harmful to the host? Indraneel Mittra Naveen Kumar Nair Pradyumna Kumar Mishra · More Details Abstract Fulltext PDF. It has been ...

  6. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. P T V Praveen Kumar. Articles written in Journal of Biosciences. Volume 38 Issue 5 December 2013 pp 887-892 Articles. Maternal hormonal interventions as a risk factor for Autism Spectrum Disorder: An epidemiological assessment from India · Madhu Poornima Mamidala Anupama ...

  7. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Sandeep Kumar. Articles written in Journal of Biosciences. Volume 33 Issue 2 June 2008 pp 269-277 Articles. Development and evaluation of an in vivo assay in Caenorhabditis elegans for screening of compounds for their effect on cytochrome P450 expression · Baby P S ...

  8. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Albert Goldbeter. Articles written in Journal of Biosciences. Volume 28 Issue 6 December 2003 pp 657-659. Commentary: Ilya Prigogine (1917–2003) · Albert Goldbeter · More Details Fulltext PDF. Volume 31 Issue 1 March 2006 pp 129-136 Articles. A model for the dynamics of ...

  9. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. BANDANA SHARAN. Articles written in Journal of Biosciences. Volume 42 Issue 1 March 2017 pp 161-173 Review. Immune modulation by dendritic-cell-based cancer vaccines · CHAITANYA KUMAR SAKSHI KOHLI POONAMALLE PARTHASARATHY BAPSY ASHOK KUMAR VAID ...

  10. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Zhu Chen. Articles written in Journal of Biosciences. Volume 25 Issue 3 September 2000 pp 275-284 Review articles. Mechanisms of all-trans retinoic acid-induced differentiation of acute promyelocytic leukemia cells · Ji-Wang Zhang Jian Gu Zhen-Yi Wang Sai-Juan Chen Zhu Chen.

  11. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. H P Puttaraju. Articles written in Journal of Biosciences. Volume 32 Issue 4 June 2007 pp 671-676 Brief communication. Frequency of infection with A and B supergroup Wolbachia in insects and pests associated with mulberry and silkworm · B M Prakash H P Puttaraju · More Details ...

  12. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. M Vaghi. Articles written in Journal of Biosciences. Volume 40 Issue 3 September 2015 pp 531-537 Articles. The potential role of myostatin and neurotransmission genes in elite sport performances · L Filonzi N Franchini M Vaghi S Chiesa F Nonnis Marzano · More Details Abstract ...

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    Home; Journals; Journal of Biosciences. Ashok Sharma. Articles written in Journal of Biosciences. Volume 32 Issue 5 August 2007 pp 999-1004 Articles. Type 2 diabetes mellitus: phylogenetic motifs for predicting protein functional sites · Ashok Sharma Tanuja Rastogi Meenakshi Bhartiya A K Shasany S P S Khanuja.

  14. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Volker Loeschcke. Articles written in Journal of Biosciences. Volume 29 Issue 4 December 2004 pp 503-511. Ecologically relevant stress resistance: from microarrays and quantitative trait loci to candidate genes – A research plan and preliminary results using Drosophila as a model ...

  15. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. NEELU ANAND JHA. Articles written in Journal of Biosciences. Volume 42 Issue 1 March 2017 pp 139-147 Article. Female conspecifics restore rhythmic singing behaviour in arrhythmic male zebra finches · NEELU ANAND JHA VINOD KUMAR · More Details Abstract Fulltext PDF.

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    Home; Journals; Journal of Biosciences. Vidya Ramachandran. Articles written in Journal of Biosciences. Volume 26 Issue 4 November 2001 pp 437-464. Epidemiological profile of India: Historical and contemporary perspectives · M D Gupte Vidya Ramachandran R K Mutatkar · More Details Abstract Fulltext PDF.

  17. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Malay Mandal. Articles written in Journal of Biosciences. Volume 28 Issue 2 March 2003 pp 205-213 Articles. Role of matrix metalloprotease-2 in oxidant activation of Ca ATPase by hydrogen peroxide in pulmonary vascular smooth muscle plasma membrane · Malay Mandal Sudip ...

  18. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Rajat K De. Articles written in Journal of Biosciences. Volume 32 Issue 5 August 2007 pp 1009-1017 Articles. Modularized study of human calcium signalling pathway · Losiana Nayak Rajat K De · More Details Abstract Fulltext PDF. Signalling pathways are complex biochemical ...

  19. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Amar J S Klar. Articles written in Journal of Biosciences. Volume 35 Issue 1 March 2010 pp 11-15 Perspectives. A proposal for re-defining the way the aetiology of schizophrenia and bipolar human psychiatric diseases is investigated · Amar J S Klar · More Details Abstract Fulltext ...

  20. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. RANJEET KUMAR. Articles written in Journal of Biosciences. Volume 41 Issue 4 December 2016 pp 689-695 ARTICLE. Reserpine requires the D2-type receptor, dop-3 , and the exoribonuclease, eri-1 , to extend the lifespan in C. elegans · KOPAL SAHARIA RANJEET KUMAR ...

  1. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Kaijing Zuo. Articles written in Journal of Biosciences. Volume 31 Issue 2 June 2006 pp 255-263 Articles. Overexpression of GbERF confers alteration of ethylene-responsive gene expression and enhanced resistance to Pseudomonas syringae in transgenic tobacco · Jie Qin Kaijing ...

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    Home; Journals; Journal of Biosciences. TAPAS C NAG. Articles written in Journal of Biosciences. Volume 39 Issue 1 March 2014 pp 107-117 Articles. Prenatal music stimulation facilitates the postnatal functional development of the auditory as well as visual system in chicks (Gallus domesticus) · Saborni Roy Tapas C Nag ...

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    Home; Journals; Journal of Biosciences. Yuquan Wei. Articles written in Journal of Biosciences. Volume 33 Issue 5 December 2008 pp 715-721 Articles. Proteomic analysis of cervical cancer cells treated with suberonylanilide hydroxamic acid · Jianxiong He Canhua Huang Aiping Tong Bin Chen Zhi Zeng Peng Zhang ...

  4. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Victor Smetacek. Articles written in Journal of Biosciences. Volume 37 Issue 4 September 2012 pp 589-607 Perspectives. Making sense of ocean biota: How evolution and biodiversity of land organisms differ from that of the plankton · Victor Smetacek · More Details Abstract Fulltext ...

  5. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Sinha Sinha. Articles written in Journal of Biosciences. Volume 39 Issue 3 June 2014 pp 525-536 Reviews. Conservation of PHO pathway in ascomycetes and the role of Pho84 · Parul Tomar Sinha Sinha · More Details Abstract Fulltext PDF. In budding yeast, Saccharomyces ...

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    Home; Journals; Journal of Biosciences. Saqib Mahmood. Articles written in Journal of Biosciences. Volume 40 Issue 3 September 2015 pp 521-530 Articles. Role of leptin G-2548A polymorphism in age- and gender-specific development of obesity · Adeela Shahid Sobia Rana Saqib Mahmood Shahid Saeed · More Details ...

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    Home; Journals; Journal of Biosciences. Hsinyu Lee. Articles written in Journal of Biosciences. Volume 37 Issue 1 March 2012 pp 157-165 Review. Autophagy: A double-edged sword in Alzheimer's disease · Ying-Tsen Tung Bo-Jeng Wang Ming-Kuan Hu Wen-Ming Hsu Hsinyu Lee Wei-Pang Huang Yung-Feng Liao.

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    Home; Journals; Journal of Biosciences. SUDHANSHU GAUTAM. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 613-621 Article. Small phosphatidate phosphatase ( TtPAH2 ) of Tetrahymena complements respiratory function and not membrane biogenesis function of yeast PAH1.

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    Home; Journals; Journal of Biosciences. STHITAPRANJYA PATI. Articles written in Journal of Biosciences. Volume 43 Issue 1 March 2018 pp 85-95 Article. Acute pharmacogenetic activation of medial prefrontal cortex excitatory neurons regulates anxiety-like behaviour · STHITAPRANJYA PATI ANKIT SOOD SOURISH ...

  10. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Antoinette Molinié. Articles written in Journal of Biosciences. Volume 38 Issue 2 June 2013 pp 189-199. Commentary: On toxic effects of scientific journals · Antoinette Molinié Geoffrey Bodenhausen · More Details Abstract Fulltext PDF. The advent of online publishing greatly ...

  11. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Will D Penny. Articles written in Journal of Biosciences. Volume 32 Issue 1 January 2007 pp 129-144 Articles. Dynamic causal models of neural system dynamics: current state and future extensions · Klaas E Stephan Lee M Harrison Stefan J Kiebel Olivier David Will D Penny Karl J ...

  12. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. N P Khairnar. Articles written in Journal of Biosciences. Volume 37 Issue 2 June 2012 pp 313-325 Review. Pyrroloquinoline-quinone and its versatile roles in biological processes · H S Misra Y S Rajpurohit N P Khairnar · More Details Abstract Fulltext PDF. Pyrroloquinoline-quinine ...

  13. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Triptish Bhatia. Articles written in Journal of Biosciences. Volume 27 Issue 1 February 2002 pp 35-52. Molecular genetics of schizophrenia: past, present and future · Suman Prasad Prachi Semwal Smita Deshpande Triptish Bhatia V L Nimgaonkar B K Thelma · More Details Abstract ...

  14. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. J P Bhatt. Articles written in Journal of Biosciences. Volume 26 Issue 2 June 2001 pp 253-263 Articles. Ovarian steroid sulphate functions as priming pheromone in male Barilius bendelisis (Ham.) J P Bhatt M S Sajwan · More Details Abstract Fulltext PDF. The study reveals that ...

  15. Journal of Biosciences | Indian Academy of Sciences

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  16. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. P Kumar. Articles written in Journal of Biosciences. Volume 33 Issue 4 November 2008 pp 475-482. Emerging influenza virus: A global threat · M Khanna P Kumar K Choudhary B Kumar V K Vijayan · More Details Abstract Fulltext PDF. Since 1918, influenza virus has been one of the ...

  17. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. PRASAD A DESHPANDE. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 647-656 Article. IGF1 stimulates differentiation of primary follicles and their growth in ovarian explants of zebrafish ( Danio rerio ) cultured in vitro · PANCHARATNA A KATTI ...

  18. Journal of Biosciences | Indian Academy of Sciences

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  19. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. B D Singh. Articles written in Journal of Biosciences. Volume 27 Issue 5 September 2002 pp 495-502 Articles. Agrobacterium-mediated transformation of cauliflower: optimization of protocol and development of Bt-transgenic cauliflower · R Chakrabarty N Viswakarma S R Bhat P B ...

  20. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. John Bernet. Articles written in Journal of Biosciences. Volume 28 Issue 3 April 2003 pp 249-264 Articles. Viral mimicry of the complement system · John Bernet Jayati Mullick Akhilesh K Singh Arvind Sahu · More Details Abstract Fulltext PDF. The complement system is a potent ...

  2. Journal of Biosciences | Indian Academy of Sciences

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  3. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Liisa A Tremere. Articles written in Journal of Biosciences. Volume 33 Issue 2 June 2008 pp 157-158. Clipboard: Recovery from amblyopia in adults via decreased visual cortical inhibition caused by experience in an enriched environment · Liisa A Tremere Raphael Pinaud.

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    Home; Journals; Journal of Biosciences. Jesper G Sørensen. Articles written in Journal of Biosciences. Volume 29 Issue 4 December 2004 pp 503-511. Ecologically relevant stress resistance: from microarrays and quantitative trait loci to candidate genes – A research plan and preliminary results using Drosophila as a ...

  5. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. SADHANA SINGH. Articles written in Journal of Biosciences. Volume 40 Issue 2 June 2015 pp 355-364 Articles. Functional and structural abnormalities associated with empathy in patients with schizophrenia: An fMRI and VBM study · Sadhana Singh Shilpi Modi Satnam Goyal ...

  6. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. MOSAMI GALVANKAR. Articles written in Journal of Biosciences. Volume 42 Issue 2 June 2017 pp 251-263 Article. Estrogen is essential but not sufficient to induce endometriosis · MOSAMI GALVANKAR NEHA SINGH MODI DEEPAK · More Details Abstract Fulltext PDF.

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  9. Journal of Biosciences | Indian Academy of Sciences

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  10. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Ying Qi. Articles written in Journal of Biosciences. Volume 32 Issue 6 September 2007 pp 1111-1118 Articles. Human cytomegalovirus UL145 gene is highly conserved among clinical strains · Zhengrong Sun Ying Lu Qiang Ruan Yaohua Ji Rong He Ying Qi Yanping Ma Yujing ...

  11. Journal of Biosciences | Indian Academy of Sciences

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  12. Journal of Biosciences | Indian Academy of Sciences

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  13. Journal of Biosciences | Indian Academy of Sciences

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  14. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. ASHWIN S SHETTY. Articles written in Journal of Biosciences. Volume 43 Issue 1 March 2018 pp 75-83 Article. PAX6 can substitute for LHX2 and override NFIA-induced astrogliogenesis in developing hippocampus in vivo · VEENA KINARE ASHWIN S SHETTY AGASTHYA ...

  15. Journal of Biosciences | Indian Academy of Sciences

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  16. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Pawan K Dhar. Articles written in Journal of Biosciences. Volume 32 Issue 5 August 2007 pp 1005-1008 Articles. The next step in biology: A periodic table? Pawan K Dhar · More Details Abstract Fulltext PDF. Systems biology is an approach to explain the behaviour of a system in ...

  17. Journal of Biosciences | Indian Academy of Sciences

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  18. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. R L Brahmachary. Articles written in Journal of Biosciences. Volume 29 Issue 3 September 2004 pp 211-212. Clipboard: Mitochondria and mind · R L Brahmachary · More Details Fulltext PDF. Volume 35 Issue 3 September 2010 pp 389-393 Articles. Designing exons for human ...

  19. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Surendra Ghaskadbi. Articles written in Journal of Biosciences. Volume 26 Issue 2 June 2001 pp 153-155 Articles. Hydra constitutively expresses transcripts involved in vertebrate neural differentiation · Sandipan Chatterjee Shweta Lahudkar N N Godbole Surendra Ghaskadbi.

  20. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Kundan Sengupta. Articles written in Journal of Biosciences. Volume 28 Issue 5 September 2003 pp 533-534. Clipboard: Human Y-chromosome: a hall of mirrors · B J Rao Kundan Sengupta · More Details Fulltext PDF ...

  2. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Tonina Fernandes. Articles written in Journal of Biosciences. Volume 35 Issue 3 September 2010 pp 427-434 Articles. Unusual radioresistance of nitrogen-fixing cultures of Anabaena strains · Harinder Singh Tonina Fernandes Shree Kumar Apte · More Details Abstract Fulltext PDF.

  3. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Shahzada Asad. Articles written in Journal of Biosciences. Volume 38 Issue 2 June 2013 pp 251-258 Articles. Bioluminescent bioreporter for assessment of arsenic contamination in water samples of India · Pratima Sharma Shahzada Asad Arif Ali · More Details Abstract Fulltext PDF.

  4. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Rachana Banerjee. Articles written in Journal of Biosciences. Volume 39 Issue 4 September 2014 pp 659-672 Articles. Conserved C-terminal nascent peptide binding domain of HYPK facilitates its chaperone-like activity · Swasti Raychaudhuri Rachana Banerjee Subhasish ...

  5. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Shinne-Ren Lin. Articles written in Journal of Biosciences. Volume 35 Issue 4 December 2010 pp 583-593 Articles. Guanidination of notexin alters its membrane-damaging activity in response to sphingomyelin and cholesterol · Pei-Hsiu Kao Yi-Ling Chiou Shinne-Ren Lin Long-Sen ...

  6. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Devkanya Dutta. Articles written in Journal of Biosciences. Volume 25 Issue 4 December 2000 pp 397-404 Mini Review. Mechanism of store-operated calcium entry · Devkanya Dutta · More Details Abstract Fulltext PDF. Activation of receptors coupled to the phospholipase C/IP3 ...

  7. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. SWATI PALIWAL. Articles written in Journal of Biosciences. Volume 42 Issue 3 September 2017 pp 373-382 Brief communication. Differential reduction of reactive oxygen species by human tissuespecific mesenchymal stem cells from different donors under oxidative stress.

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    Home; Journals; Journal of Biosciences. Stephen S Leonard. Articles written in Journal of Biosciences. Volume 28 Issue 1 February 2003 pp 13-18. Role of metal-induced reactive oxygen species generation in lung responses caused by residual oil fly ash · Anthony B Lewis Michael D Taylor Jenny R Roberts Stephen S ...

  9. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. JW JAHNG. Articles written in Journal of Biosciences. Volume 42 Issue 1 March 2017 pp 131-138 Article. Early life stress experience may blunt hypothalamic leptin signalling · JH LEE SB YOO JY KIM JY LEE BT KIM K PARK JW JAHNG · More Details Abstract Fulltext PDF. The aim ...

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    Home; Journals; Journal of Biosciences. KAMAL SABA. Articles written in Journal of Biosciences. Volume 42 Issue 3 September 2017 pp 363-371 Brief communication. Amalaki Rasayana improved memory and neuronal metabolic activity in AβPP-PS1 mouse model of Alzheimer's disease · VIVEK TIWARI KAMAL SABA ...

  12. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Partha P Majumder. Articles written in Journal of Biosciences. Volume 26 Issue 4 November 2001 pp 390a-390a. Preface · Partha P Majumder A Jagannadha Rao · More Details Fulltext PDF. Volume 26 Issue 4 November 2001 pp 533-545. Ethnic populations of India as seen from ...

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    Home; Journals; Journal of Biosciences. DJALMA M DE OLIVEIRA. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 657-664 Article. In vitro leishmanicidal, antibacterial and antitumour potential of anhydrocochlioquinone A obtained from the fungus Cochliobolus sp. FERNANDA F CAMPOS ...

  17. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Zhengrong Sun. Articles written in Journal of Biosciences. Volume 32 Issue 6 September 2007 pp 1111-1118 Articles. Human cytomegalovirus UL145 gene is highly conserved among clinical strains · Zhengrong Sun Ying Lu Qiang Ruan Yaohua Ji Rong He Ying Qi Yanping Ma ...

  18. Journal of Biosciences | Indian Academy of Sciences

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  20. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. R S Sharma. Articles written in Journal of Biosciences. Volume 26 Issue 4 November 2001 pp 391-405. Current status of fertility control methods in India · R S Sharma M Rajalakshmi D Antony Jeyaraj · More Details Abstract Fulltext PDF. Approximately 48.2% of couples of 15 to 49 ...

  2. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. SHREE KUMAR APTE. Articles written in Journal of Biosciences. Volume 29 Issue 2 June 2004 pp 153-161 Articles. A novel potassium deficiency-induced stimulon in Anabaena torulosa · Anuradha Alahari Shree Kumar Apte · More Details Abstract Fulltext PDF. Potassium ...

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    Home; Journals; Journal of Biosciences. T Moreno. Articles written in Journal of Biosciences. Volume 28 Issue 1 February 2003 pp 101-107. Pulmonary antioxidants exert differential protective effects against urban and industrial particulate matter · L L Greenwell T Moreno R J Richards · More Details Abstract Fulltext PDF.

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    Home; Journals; Journal of Biosciences. Ashwin Kotnis. Articles written in Journal of Biosciences. Volume 30 Issue 1 February 2005 pp 93-102. Genotype, phenotype and cancer: Role of low penetrance genes and environment in tumour susceptibility · Ashwin Kotnis Rajiv Sarin Rita Mulherkar · More Details Abstract Fulltext ...

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    Home; Journals; Journal of Biosciences. ZAKI ABU RABI. Articles written in Journal of Biosciences. Volume 42 Issue 2 June 2017 pp 265-274 Article. Interleukin 8 in progression of hormone-dependent early breast cancer · JELENA MILOVANOVIĆ NATAŠA TODOROVIĆ-RAKOVIĆ TIJANA VUJASINOVIĆ ZAKI ABU RABI.

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    Home; Journals; Journal of Biosciences. Alok Sharma. Articles written in Journal of Biosciences. Volume 32 Issue 6 September 2007 pp 1089-1110 Articles. Multiplicity of carbohydrate-binding sites in -prism fold lectins: occurrence and possible evolutionary implications · Alok Sharma Divya Chandran Desh D Singh M ...

  10. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Anurag Kumar Mishra. Articles written in Journal of Biosciences. Volume 27 Issue 3 June 2002 pp 251-259 Articles. Cloning and sequencing of complete -crystallin cDNA from embryonic lens of Crocodylus palustris · Raman Agrawal Reena Chandrashekhar Anurag Kumar Mishra ...

  11. Journal of Biosciences | Indian Academy of Sciences

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  12. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Ardashir K Masouleh. Articles written in Journal of Biosciences. Volume 37 Issue 5 November 2012 pp 829-841 Articles. Application of large-scale sequencing to marker discovery in plants · Robert J Henry Mark Edwards Daniel L E Waters S Gopala Krishnan Peter Bundock Timothy ...

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    Home; Journals; Journal of Biosciences. G P Talwar. Articles written in Journal of Biosciences. Volume 30 Issue 4 September 2005 pp 435-447 Perspectives. A destiny to fulfill · G P Talwar · More Details Fulltext PDF. Volume 34 Issue 6 December 2009 pp 909-916 Articles. A partner monoclonal antibody to Moab 730 kills ...

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    Home; Journals; Journal of Biosciences. MANUELA NAGEL. Articles written in Journal of Biosciences. Volume 37 Issue 5 November 2012 pp 871-877 Articles. Molecular markers in management of ex situ PGR - A case study · Andreas Börner Elena K Khlestkina Sabina Chebotar Manuela Nagel Mian Abdur Rehman Arif ...

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  18. Journal of Biosciences | Indian Academy of Sciences

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  20. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. V Kumar. Articles written in Journal of Biosciences. Volume 39 Issue 3 June 2014 pp 485-491 Articles. Life at a different pace: Annual itineraries are conserved in seasonal songbirds · S Malik S Singh S Rani V Kumar · More Details Abstract Fulltext PDF. The duration of life history ...

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    Home; Journals; Journal of Biosciences. T Raj. Articles written in Journal of Biosciences. Volume 31 Issue 2 June 2006 pp 273-280 Articles. Bicarbonate kinetics in Indian males · T Raj R Kuriyan A V Kurpad · More Details Abstract Fulltext PDF. Measurement of rates of in vivo substrate oxidation such as that of glucose, fatty ...

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    Home; Journals; Journal of Biosciences. Hong Chen. Articles written in Journal of Biosciences. Volume 33 Issue 3 September 2008 pp 365-370 Articles. The polymorphisms of bovine cocaine- and amphetamine-regulated transcripts and their associations with cattle (Bos taurus) growth traits · Chun Lei Zhang Hong Chen ...

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    Home; Journals; Journal of Biosciences. Kaushlendra Tripathi. Articles written in Journal of Biosciences. Volume 29 Issue 1 March 2004 pp 23-31 Articles. Dibutyryl c-AMP as an inducer of sporidia formation: Biochemical and antigenic changes during morphological differentiation of Karnal bunt (Tilletia indica) pathogen in ...

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    Home; Journals; Journal of Biosciences. G M Bhopale. Articles written in Journal of Biosciences. Volume 28 Issue 6 December 2003 pp 783-789 Review. Blood coagulation factor VIII: An overview · G M Bhopale R K Nanda · More Details Abstract Fulltext PDF. Factor VIII (FVIII) functions as a co-factor in the blood ...

  10. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Rajendra Prasad. Articles written in Journal of Biosciences. Volume 26 Issue 3 September 2001 pp 333-339 Articles. Specificity of drug transport mediated by CaMDR1: a major facilitator of Candida albicans · Avmeet Kohli Vinita Gupta Shankarling Krishnamurthy Seyed E Hasnain ...

  11. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Anupama Polinedi. Articles written in Journal of Biosciences. Volume 38 Issue 5 December 2013 pp 887-892 Articles. Maternal hormonal interventions as a risk factor for Autism Spectrum Disorder: An epidemiological assessment from India · Madhu Poornima Mamidala Anupama ...

  16. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Q M I Haq. Articles written in Journal of Biosciences. Volume 36 Issue 2 June 2011 pp 329-340 Articles. Mutagenesis in ORF AV2 affects viral replication in Mungbean yellow mosaic India virus · A Rouhibakhsh Q M I Haq V G Malathi · More Details Abstract Fulltext PDF. Mungbean ...

  17. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Bhavneesh Sharma. Articles written in Journal of Biosciences. Volume 28 Issue 1 February 2003 pp 7-11. Effects of exogenous vitamin E supplementation on the levels of oxidants and antioxidants in chronic obstructive pulmonary disease · M K Daga Rashmi Chhabra Bhavneesh ...

  18. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. D Raghunath. Articles written in Journal of Biosciences. Volume 33 Issue 4 November 2008 pp 593-603. Emerging antibiotic resistance in bacteria with special reference to India · D Raghunath · More Details Abstract Fulltext PDF. The antibiotic era started in the 1940s and changed ...

  19. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Finny Monickaraj. Articles written in Journal of Biosciences. Volume 38 Issue 1 March 2013 pp 113-122 Articles. Accelerated fat cell aging links oxidative stress and insulin resistance in adipocytes · Finny Monickaraj Sankaramoorthy Aravind Pichamoorthy Nandhini Paramasivam ...

  20. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. PRABHJOT KAUR. Articles written in Journal of Biosciences. Volume 40 Issue 2 June 2015 pp 355-364 Articles. Functional and structural abnormalities associated with empathy in patients with schizophrenia: An fMRI and VBM study · Sadhana Singh Shilpi Modi Satnam Goyal ...

  1. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Michelle Williams. Articles written in Journal of Biosciences. Volume 38 Issue 1 March 2013 pp 73-83 Articles. Vps1 in the late endosome-to-vacuole traffic · Jacob Hayden Michelle Williams Ann Granich Hyoeun Ahn Brandon Tenay Joshua Lukehart Chad Highfill Sarah Dobard ...

  2. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. P Vijayachari. Articles written in Journal of Biosciences. Volume 33 Issue 4 November 2008 pp 557-569. Leptospirosis: an emerging global public health problem · P Vijayachari A P Sugunan A N Shriram · More Details Abstract Fulltext PDF. Leptospirosis has been recognized as an ...

  3. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Mian Abdur Rehman Arif. Articles written in Journal of Biosciences. Volume 37 Issue 5 November 2012 pp 871-877 Articles. Molecular markers in management of ex situ PGR - A case study · Andreas Börner Elena K Khlestkina Sabina Chebotar Manuela Nagel Mian Abdur Rehman ...

  4. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Deepak Bajaj. Articles written in Journal of Biosciences. Volume 38 Issue 5 December 2013 pp 971-987 Reviews. Integrated genomics and molecular breeding approaches for dissecting the complex quantitative traits in crop plants · Alice Kujur Maneesha S Saxena Deepak Bajaj ...

  5. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Indranil Dasgupta. Articles written in Journal of Biosciences. Volume 37 Issue 4 September 2012 pp 791-806 Review. Begomovirus research in India: A critical appraisal and the way ahead · Basanta K Borah Indranil Dasgupta · More Details Abstract Fulltext PDF. Begomoviruses are ...

  6. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Shree Kumar Apte. Articles written in Journal of Biosciences. Volume 29 Issue 2 June 2004 pp 153-161 Articles. A novel potassium deficiency-induced stimulon in Anabaena torulosa · Anuradha Alahari Shree Kumar Apte · More Details Abstract Fulltext PDF. Potassium deficiency ...

  7. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. SHUGUANG HAN. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 671-681 Article. MiR-876-5p suppresses epithelial-mesenchymal transition of lung cancer by directly down-regulating bone morphogenetic protein 4 · LIANG BAO LEI LV JINPING ...

  8. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Suman Jain. Articles written in Journal of Biosciences. Volume 38 Issue 3 September 2013 pp 605-614 Reviews. Role of sound stimulation in reprogramming brain connectivity · Sraboni Chaudhury Tapas C Nag Suman Jain Shashi Wadhwa · More Details Abstract Fulltext PDF.

  9. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Sanjeev Kumar. Articles written in Journal of Biosciences. Volume 29 Issue 4 December 2004 pp 471-487. Heat stress response in plants: a complex game with chaperones and more than twenty heat stress transcription factors · Sanjeev Kumar Baniwal Kapil Bharti Kwan Yu Chan ...

  10. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Preeti Rawat. Articles written in Journal of Biosciences. Volume 34 Issue 2 June 2009 pp 199-202 Brief communication. Inactivation of a transgene due to transposition of insertion sequence (IS136) of Agrobacterium tumefaciens · Preeti Rawat Sanjeev Kumar Deepak Pental ...

  11. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. N Singh. Articles written in Journal of Biosciences. Volume 38 Issue 5 December 2013 pp 905-915 Articles. Assessment of lexical semantic judgment abilities in alcohol-dependent subjects: An fMRI study · D Bagga N Singh S Modi P Kumar D Bhattacharya M L Garg S Khushu.

  12. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Rajiva Raman. Articles written in Journal of Biosciences. Volume 38 Issue 1 March 2013 pp 21-26 Brief communications. Lower incidence of nonsyndromic cleft lip with or without cleft palate in females: Is homocysteine a factor? Priyanka Kumari Akhtar Ali Krishna K Sukla Subodh K ...

  13. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Pooran M Gaur. Articles written in Journal of Biosciences. Volume 37 Issue 5 November 2012 pp 811-820 Articles. Advances in genetics and molecular breeding of three legume crops of semi-arid tropics using next-generation sequencing and high-throughput genotyping ...

  14. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. JASWANDI UJWAL DANDEKAR. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 585-601 Article. Fermentative metabolism impedes p53-dependent apoptosis in a Crabtree-positive but not in Crabtree-negative yeast · ABHAY KUMAR JASWANDI ...

  15. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Marta Linde-Medina. Articles written in Journal of Biosciences. Volume 36 Issue 4 September 2011 pp 575-585 Brief communication. Adaptation or exaptation? The case of the human hand · Marta Linde-Medina · More Details Abstract Fulltext PDF. A controversy of relevance to the ...

  16. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Seungwan Jee. Articles written in Journal of Biosciences. Volume 32 Issue 4 June 2007 pp 723-735 Articles. Selenium acts as an insulin-like molecule for the down-regulation of diabetic symptoms via endoplasmic reticulum stress and insulin signalling proteins in diabetes-induced ...

  17. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. AGASTHYA SURESH. Articles written in Journal of Biosciences. Volume 43 Issue 1 March 2018 pp 75-83 Article. PAX6 can substitute for LHX2 and override NFIA-induced astrogliogenesis in developing hippocampus in vivo · VEENA KINARE ASHWIN S SHETTY AGASTHYA ...

  18. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. JOYOUS T JOSEPH. Articles written in Journal of Biosciences. Volume 43 Issue 1 March 2018 pp 173-187 Review. Plant reference genes for development and stress response studies · JOYOUS T JOSEPH NAJYA JABEEN POOLAKKALODY JASMINE M SHAH · More Details ...

  19. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Mamta Upadhyay. Articles written in Journal of Biosciences. Volume 40 Issue 5 December 2015 pp 863-871 Articles. Interdependence of laforin and malin proteins for their stability and functions could underlie the molecular basis of locus heterogeneity in Lafora disease.

  20. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Vasanthi Nachiappan. Articles written in Journal of Biosciences. Volume 31 Issue 5 December 2006 pp 599-605 Reviews. Potential application of urea-derived herbicides as cytokinins in plant tissue culture · Malathi Srinivasan Vasanthi Nachiappan Ram Rajasekharan.

  1. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Anshu Aggarwal. Articles written in Journal of Biosciences. Volume 27 Issue 4 July 2002 pp 339-346 Articles. Place prioritization for biodiversity content · Sahotra Sarkar Anshu Aggarwal Justin Garson Chris R Margules Juliane Zeidler · More Details Abstract Fulltext PDF.

  2. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Lidia Andreu Guillo. Articles written in Journal of Biosciences. Volume 37 Issue 1 March 2012 pp 33-39 Articles. TP53 codon 72 polymorphism in pigmentary phenotypes · Kárita Antunes Costa Lidia Andreu Guillo · More Details Abstract Fulltext PDF. The p53 protein exerts different ...

  3. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Stuart A Newman. Articles written in Journal of Biosciences. Volume 27 Issue 2 March 2002 pp 97-104 Perspectives. Developmental mechanisms: putting genes in their place · Stuart A Newman · More Details Fulltext PDF. Volume 27 Issue 5 September 2002 pp 448-449.

  4. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. T Naga Sowjanya. Articles written in Journal of Biosciences. Volume 35 Issue 4 December 2010 pp 539-546 Articles. Translocations used to generate chromosome segment duplications in Neurospora can disrupt genes and create novel open reading frames · Parmit K Singh ...

  5. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. M Balasubramanyam. Articles written in Journal of Biosciences. Volume 26 Issue 3 September 2001 pp 383-390 Review Article. Orally active insulin mimics: where do we stand now? M Balasubramanyam V Mohan · More Details Abstract Fulltext PDF. The war against diabetes ...

  6. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Leelavinothan Pari. Articles written in Journal of Biosciences. Volume 31 Issue 5 December 2006 pp 581-587 Articles. Effect of a novel insulinotropic agent, succinic acid monoethyl ester, on lipids and lipoproteins levels in rats with streptozotocin-nicotinamideinduced type 2 diabetes.

  7. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Chandan Kumar-Sinha. Articles written in Journal of Biosciences. Volume 33 Issue 1 March 2008 pp 73-80 Articles. Human papillomavirus genotyping by multiplex pyrosequencing in cervical cancer patients from India · Cheryl M Travasso Mona Anand Mansi Mansi Samarth Aditi ...

  8. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. VIBHA DWIVEDI. Articles written in Journal of Biosciences. Volume 40 Issue 2 June 2015 pp 281-297 Articles. Suppression of induced but not developmental apoptosis in Drosophila by Ayurvedic Amalaki Rasayana and Rasa-Sindoor · Vibha Dwivedi Shweta Tiwary Subhash C ...

  9. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Arvind Kumar. Articles written in Journal of Biosciences. Volume 37 Issue 6 December 2012 pp 1041-1059 Articles. COCHLEATA controls leaf size and secondary inflorescence architecture via negative regulation of UNIFOLIATA (LEAFY ortholog) gene in garden pea Pisum sativum.

  10. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Chaitrali Umranikar. Articles written in Journal of Biosciences. Volume 32 Issue 4 June 2007 pp 769-774 Articles. Presence of two types of flowers with respect to nectar sugar in two gregariously flowering species · Chaitali Anand Chaitrali Umranikar Pooja Shintre Anuja Damle ...

  11. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. VIDYANAND NANJUNDIAH. Articles written in Journal of Biosciences. Volume 25 Issue 1 March 2000 pp 9-10. Commentary: The smallest form of life yet? Vidyanand Nanjundiah · More Details Fulltext PDF. Volume 28 Issue 6 December 2003 pp 697-707 Articles. Calcium regulates ...

  12. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. RENFU CHEN. Articles written in Journal of Biosciences. Volume 41 Issue 2 June 2016 pp 229-236 Article. Silencing of HMGA2 promotes apoptosis and inhibits migration and invasion of prostate cancer cells · Zhan Shi Ding Wu Run Tang Xiang Li Renfu Chen Song Xue Chengjing ...

  13. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. SHRUTI D MARATHE. Articles written in Journal of Biosciences. Volume 42 Issue 3 September 2017 pp 481-490 Article. Promoter polymorphism MMP-1 (-1607 2G/1G) and MMP-3 (-1612 5A/6A) in development of HAND and modulation of pathogenesis of HAND · HARI OM SINGH ...

  14. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. DR BHATTACHARYYA. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 531-535 Brief communication. Antifolate drug resistance: Novel mutations and haplotype distribution in dhps and dhfr from Northeast India · NP SARMAH K SARMA DR ...

  15. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. SURESH KUMAR SAWANTH. Articles written in Journal of Biosciences. Volume 41 Issue 4 December 2016 pp 805-805 ERRATUM. The autoregulatory loop: A common mechanism of regulation of key sex determining genes in insects · SURESH KUMAR SAWANTH GAJULA ...

  16. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. R S Radder. Articles written in Journal of Biosciences. Volume 27 Issue 5 September 2002 pp 529-537 Articles. Members of opposite sex mutually regulate gonadal recrudescence in the lizard Calotes versicolor (Agamidae) · B A Shanbhag R S Radder S K Saidapur · More Details ...

  17. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. T Capriglione. Articles written in Journal of Biosciences. Volume 32 Issue 4 June 2007 pp 763-768 Articles. Cytological evidence for population-specific sex chromosome heteromorphism in Palaearctic green toads (Amphibia, Anura) · G Odierna G Aprea T Capriglione S Castellano E ...

  18. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Awtar Kishen Koul. Articles written in Journal of Biosciences. Volume 34 Issue 6 December 2009 pp 977-990 Articles. Sex expression and breeding strategy in Commelina benghalensis L. Veenu Kaul Awtar Kishen Koul · More Details Abstract Fulltext PDF. This paper describes the ...

  19. East Midlands healthcare and bioscience sector strategy

    OpenAIRE

    East Midlands Development Agency

    2007-01-01

    The healthcare and bioscience sector is one of four priority sectors identified in the regional economic strategy, A Flourishing Region. This document sets out a strategy for maximising the contribution of the healthcare and biosciences sector to the economic development of the East Midlands.

  20. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Michel Morange. Articles written in Journal of Biosciences. Volume 29 Issue 4 December 2004 pp 378-380. Commentary: The death of Francis Crick: the end of a golden age in biology · Michel Morange · More Details Fulltext PDF. Volume 30 Issue 3 June 2005 pp 313-316 Series.

  1. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Pankaj Verma. Articles written in Journal of Biosciences. Volume 37 Issue 2 June 2012 pp 221-226 Brief communication. Molecular typing of fecal eukaryotic microbiota of human infants and their respective mothers · Prashant K Pandey Jay Siddharth Pankaj Verma Ashish Bavdekar ...

  2. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Anindita Bhattacharyya. Articles written in Journal of Biosciences. Volume 27 Issue 5 September 2002 pp 503-508 Articles. Studies on Stibanate unresponsive isolates of Leishmania donovani · Anindita Bhattacharyya Mandira Mukherjee Swadesh Duttagupta · More Details Abstract ...

  3. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. ATHEL CORNISH-BOWDEN. Articles written in Journal of Biosciences. Volume 27 Issue 2 March 2002 pp 121-126 Articles. Enthalpy–entropy compensation: a phantom phenomenon · Athel Cornish-Bowden · More Details Abstract Fulltext PDF. Enthalpy–entropy compensation is the ...

  4. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Zaiba Y Kharbuli. Articles written in Journal of Biosciences. Volume 28 Issue 6 December 2003 pp 733-742 Articles. Role of ureogenesis in tackling problems of ammonia toxicity during exposure to higher ambient ammonia in the air-breathing walking catfish Clarias batrachus.

  5. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Naveen Kumar. Articles written in Journal of Biosciences. Volume 32 Issue 5 August 2007 pp 937-945 Articles. ARC: Automated Resource Classifier for agglomerative functional classification of prokaryotic proteins using annotation texts · Muthiah Gnanamani Naveen Kumar ...

  6. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Murlidhar J Mendki. Articles written in Journal of Biosciences. Volume 38 Issue 2 June 2013 pp 301-309 Articles. Transcriptome analysis of Anopheles stephensi embryo using expressed sequence tags · Kaustubh Gokhale Deepak P Patil Dhiraj P Dhotre Rajnikant Dixit Murlidhar J ...

  7. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Antonio G Valdecasas. Articles written in Journal of Biosciences. Volume 34 Issue 6 December 2009 pp 835-843 Perspectives. Understanding complex systems: lessons from Auzoux's and von Hagens's anatomical models · Antonio G Valdecasas Ana M Correas Carmen R Guerrero ...

  8. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. D BANSAL. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 531-535 Brief communication. Antifolate drug resistance: Novel mutations and haplotype distribution in dhps and dhfr from Northeast India · NP SARMAH K SARMA DR BHATTACHARYYA ...

  9. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. HIMANI DEY. Articles written in Journal of Biosciences. Volume 42 Issue 2 June 2017 pp 333-344 Review. Regulation of dynamin family proteins by post-translational modifications · USHA P KAR HIMANI DEY ABDUR RAHAMAN · More Details Abstract Fulltext PDF. Dynamin ...

  10. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Chen Fang. Articles written in Journal of Biosciences. Volume 30 Issue 3 June 2005 pp 351-357 Articles. Expression of a ribosome inactivating protein (curcin 2) in Jatropha curcas is induced by stress · Wei Qin Huang Ming-Xing Xu Ying Zhang Xin-Shen Chen Fang · More Details ...

  11. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. B N Singh. Articles written in Journal of Biosciences. Volume 34 Issue 2 June 2009 pp 263-274 Articles. Variations in morphological and life-history traits under extreme temperatures in Drosophila ananassae · Seema Sisodia B N Singh · More Details Abstract Fulltext PDF.

  12. Journal of Biosciences | Indian Academy of Sciences

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  13. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Subash Khushu. Articles written in Journal of Biosciences. Volume 40 Issue 2 June 2015 pp 355-364 Articles. Functional and structural abnormalities associated with empathy in patients with schizophrenia: An fMRI and VBM study · Sadhana Singh Shilpi Modi Satnam Goyal Prabhjot ...

  14. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Priyakshi Mahanta. Articles written in Journal of Biosciences. Volume 39 Issue 3 June 2014 pp 351-364 Articles. FUMET: A fuzzy network module extraction technique for gene expression data · Priyakshi Mahanta Hasin Afzal Ahmed Dhruba Kumar Bhattacharyya Ashish Ghosh.

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    Home; Journals; Journal of Biosciences. Kamalvishnu P Gottimukkala. Articles written in Journal of Biosciences. Volume 36 Issue 3 August 2011 pp 461-469 Articles. N-terminal PDZ-like domain of chromatin organizer SATB1 contributes towards its function as transcription regulator · Dimple Notani Praveena L Ramanujam ...

  16. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Xiuhong Yang. Articles written in Journal of Biosciences. Volume 33 Issue 1 March 2008 pp 103-112 Articles. Molecular cloning and characterization of a gene encoding RING zinc finger ankyrin protein from drought-tolerant Artemisia desertorum · Xiuhong Yang Chao Sun Yuanlei ...

  17. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. XIAOQIAN DING. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 637-645 Article. MicroRNA-146 protects A549 and H1975 cells from LPS-induced apoptosis and inflammation injury · QIANG WANG DAGANG LI YUQUAN HAN XIAOQIAN DING TAO ...

  18. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. MASOUD SOLEIMANI. Articles written in Journal of Biosciences. Volume 42 Issue 1 March 2017 pp 23-30 Article. Overexpression of hsa-miR-939 follows by NGFR down-regulation and apoptosis reduction · FAHIMEH HOSSEINI AGHDAEI BAHRAM M SOLTANI SADAT ...

  19. Journal of Biosciences | Indian Academy of Sciences

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  20. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Annarita Ciana. Articles written in Journal of Biosciences. Volume 30 Issue 3 June 2005 pp 317-328 Articles. Detergent-resistant membranes in human erythrocytes and their connection to the membrane-skeleton · Annarita Ciana Cesare Balduini Giampaolo Minetti · More Details ...

  1. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. JILL P PARSONS. Articles written in Journal of Biosciences. Volume 42 Issue 2 June 2017 pp 321-331 Review. An evaluation of the status of living collections for plant, environmental, and microbial research · KEVIN MCCLUSKEY JILL P PARSONS KIMBERLY QUACH CLIFFORD S ...

  2. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. JONAS P RAMOS. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 657-664 Article. In vitro leishmanicidal, antibacterial and antitumour potential of anhydrocochlioquinone A obtained from the fungus Cochliobolus sp. FERNANDA F CAMPOS JONAS ...

  3. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Pichamoorthy Nandhini. Articles written in Journal of Biosciences. Volume 38 Issue 1 March 2013 pp 113-122 Articles. Accelerated fat cell aging links oxidative stress and insulin resistance in adipocytes · Finny Monickaraj Sankaramoorthy Aravind Pichamoorthy Nandhini ...

  4. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. A I Bhat. Articles written in Journal of Biosciences. Volume 30 Issue 3 June 2005 pp 339-350 Articles. Occurrence of Cucumber mosaic virus on vanilla (Vanilla planifolia Andrews) in India · R Madhubala V Bhadramurthy A I Bhat P S Hareesh S T Retheesh R S Bhai · More Details ...

  5. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. S A Kulasooriya. Articles written in Journal of Biosciences. Volume 31 Issue 5 December 2006 pp 645-650 Reviews. Interactions among endophytic bacteria and fungi: effects and potentials · W M M S Bandara Gamini Seneviratne S A Kulasooriya · More Details Abstract Fulltext PDF.

  6. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. MICHEL MORANGE. Articles written in Journal of Biosciences. Volume 29 Issue 4 December 2004 pp 378-380. Commentary: The death of Francis Crick: the end of a golden age in biology · Michel Morange · More Details Fulltext PDF. Volume 30 Issue 3 June 2005 pp 313-316 ...

  7. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Mario U Mondelli. Articles written in Journal of Biosciences. Volume 28 Issue 3 April 2003 pp 305-310 Articles. Variability or conservation of hepatitis C virus hypervariable region 1? Implications for immune responses · Mario U Mondelli Antonella Cerino Annalisa Meola Alfredo ...

  8. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. SONG XUE. Articles written in Journal of Biosciences. Volume 41 Issue 2 June 2016 pp 229-236 Article. Silencing of HMGA2 promotes apoptosis and inhibits migration and invasion of prostate cancer cells · Zhan Shi Ding Wu Run Tang Xiang Li Renfu Chen Song Xue Chengjing ...

  9. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. JAMUNA R SUBRAMANIAM. Articles written in Journal of Biosciences. Volume 41 Issue 4 December 2016 pp 689-695 ARTICLE. Reserpine requires the D2-type receptor, dop-3 , and the exoribonuclease, eri-1 , to extend the lifespan in C. elegans · KOPAL SAHARIA RANJEET ...

  10. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Ramyani Taran. Articles written in Journal of Biosciences. Volume 39 Issue 1 March 2014 pp 157-169 Reviews. In vitro and in vivo neurogenic potential of mesenchymal stem cells isolated from different sources · Ramyani Taran MamidiMurali Krishna Gurbind Singh Susmita Dutta ...

  11. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Ritu Sarpal. Articles written in Journal of Biosciences. Volume 27 Issue 5 September 2002 pp 479-487 Articles. Dynamic expression pattern of kinesin accessory protein in Drosophila · Ritu Sarpal Krishanu Ray · More Details Abstract Fulltext PDF. We have identified the Drosophila ...

  12. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Sanjay Kumar. Articles written in Journal of Biosciences. Volume 30 Issue 2 March 2005 pp 231-235 Articles. Differential display-mediated identification of three drought-responsive expressed sequence tags in tea [Camellia sinensis (L.) O. Kuntze] · Priti Sharma Sanjay Kumar.

  13. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Tarini Shankar Ghosh. Articles written in Journal of Biosciences. Volume 36 Issue 4 September 2011 pp 709-717 Articles. Eu-Detect: An algorithm for detecting eukaryotic sequences in metagenomic data sets · Monzoorul Haque Mohammed Sudha Chadaram Dinakar Dinakar ...

  14. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Sharmila S Mande. Articles written in Journal of Biosciences. Volume 35 Issue 3 September 2010 pp 351-364 Articles. INDeGenIUS, a new method for high-throughput identification of specialized functional islands in completely sequenced organisms · Sakshi Shrivastava Ch V Siva ...

  15. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Shikha Srivastava. Articles written in Journal of Biosciences. Volume 37 Issue 1 March 2012 pp 63-72 Articles. High prevalence of oncogenic HPV-16 in cervical smears of asymptomatic women of eastern Uttar Pradesh, India: A population-based study · Shikha Srivastava Sadhana ...

  16. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Abhay Harsulkar. Articles written in Journal of Biosciences. Volume 32 Issue 2 March 2007 pp 299-307 Articles. Chondroprotective potential of root extracts of Withania somnifera in osteoarthritis · Venil N Sumantran Asavari Kulkarni Sanjay Boddul Trushna Chinchwade Soumya J ...

  17. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Subramaniam Ganesh. Articles written in Journal of Biosciences. Volume 30 Issue 5 December 2005 pp 561-566. Commentary: Neuronal survival in epilepsy: to die or not to die? Subramaniam Ganesh Shweta Singh · More Details Fulltext PDF. Volume 33 Issue 2 June 2008 pp ...

  18. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. David L Beveridge. Articles written in Journal of Biosciences. Volume 37 Issue 3 July 2012 pp 379-397 Articles. The ABCs of molecular dynamics simulations on B-DNA, circa 2012 · David L Beveridge Thomas E Cheatham III Mihaly Mezei · More Details Abstract Fulltext PDF.

  19. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. JEDY JOSE. Articles written in Journal of Biosciences. Volume 42 Issue 3 September 2017 pp 363-371 Brief communication. Amalaki Rasayana improved memory and neuronal metabolic activity in AβPP-PS1 mouse model of Alzheimer's disease · VIVEK TIWARI KAMAL SABA ...

  20. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. ANANT B PATEL. Articles written in Journal of Biosciences. Volume 42 Issue 3 September 2017 pp 363-371 Brief communication. Amalaki Rasayana improved memory and neuronal metabolic activity in AβPP-PS1 mouse model of Alzheimer's disease · VIVEK TIWARI KAMAL SABA ...

  1. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Girish J Kotwal. Articles written in Journal of Biosciences. Volume 28 Issue 3 April 2003 pp 265-271 Articles. Vaccinia complement control protein: Multi-functional protein and a potential wonder drug · Purushottam Jha Girish J Kotwal · More Details Abstract Fulltext PDF. Vaccinia ...

  2. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Rahul Gaur. Articles written in Journal of Biosciences. Volume 32 Issue 4 June 2007 pp 747-754 Articles. Diet-dependent depletion of queuosine in tRNAs in Caenorhabditis elegans does not lead to a developmental block · Rahul Gaur Glenn R Björk Simon Tuck Umesh Varshney.

  3. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Taznim Begam Mohd Mohidin. Articles written in Journal of Biosciences. Volume 40 Issue 1 March 2015 pp 41-51 Articles. BARF1 gene silencing triggers caspase-dependent mitochondrial apoptosis in Epstein-Barr virus-positive malignant cells · Taznim Begam Mohd Mohidin Ching ...

  4. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Vibha Tandon. Articles written in Journal of Biosciences. Volume 37 Issue 3 July 2012 pp 493-502 Articles. Inhibition of HIV-1 Integrase gene expression by 10-23 DNAzyme · Nirpendra Singh Atul Ranjan Souvik Sur Ramesh Chandra Vibha Tandon · More Details Abstract Fulltext ...

  5. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Yu Zeng. Articles written in Journal of Biosciences. Volume 29 Issue 1 March 2004 pp 67-71 Articles. An optimized gossypol high-performance liquid chromatography assay and its application in evaluation of different gland genotypes of cotton · Yingfan Cai Hong Zhang Yu Zeng ...

  6. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Rajkumar S. Articles written in Journal of Biosciences. Volume 29 Issue 1 March 2004 pp 105-110 Articles. Factors influencing offspring traits in the oviparous multi-clutched lizard, Calotes versicolor (Agamidae) · Rajkumar S Radder Bhagyashri A Shanbhag · More Details Abstract ...

  7. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Journal of Biosciences. Current Issue : Vol. 43, Issue 1. Current Issue Volume 43 | Issue 1. March 2018. Home · Volumes & Issues · Special Issues · Forthcoming Articles · Gallery of Cover Art · Search · Online submission at eBiosciences · Editorial Board · Information for Authors · Subscription ...

  8. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Marie Beurton-Aimar. Articles written in Journal of Biosciences. Volume 32 Issue 1 January 2007 pp 145-155 Articles. Formal TCA cycle description based on elementary actions · Pierre Mazière Nicolas Parisey Marie Beurton-Aimar Franck Molina · More Details Abstract Fulltext PDF.

  9. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. ASHIS KUMAR NANDI. Articles written in Journal of Biosciences. Volume 38 Issue 3 September 2013 pp 583-592 Articles. Down-regulation of OsSAG12-1 results in enhanced senescence and pathogen-induced cell death in transgenic rice plants · Subaran Singh Mrunmay Kumar ...

  10. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. NARAHARI P GRAMAPUROHIT. Articles written in Journal of Biosciences. Volume 42 Issue 3 September 2017 pp 459-468 Article. Can embryonic skipper frogs ( Euphlyctis cyanophlyctis ) learn to recognise kairomones in the absence of a nervous system? SWAPNIL C SUPEKAR ...

  11. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Ram Rajasekharan. Articles written in Journal of Biosciences. Volume 31 Issue 5 December 2006 pp 599-605 Reviews. Potential application of urea-derived herbicides as cytokinins in plant tissue culture · Malathi Srinivasan Vasanthi Nachiappan Ram Rajasekharan · More Details ...

  12. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. R Jayaraman. Articles written in Journal of Biosciences. Volume 31 Issue 1 March 2006 pp 31-45 Articles. Allele-specific suppression of the temperature sensitivity of fitA/fitB mutants of Escherichia coli by a new mutation (fitC4): isolation, characterization and its implications in ...

  13. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. POOJA SHARMA. Articles written in Journal of Biosciences. Volume 42 Issue 3 September 2017 pp 383-396 Article. Protein complex finding and ranking: An application to Alzheimer's disease · POOJA SHARMA DHRUBA K BHATTACHARYYA JUGAL K KALITA · More Details ...

  14. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Narinder Kaur. Articles written in Journal of Biosciences. Volume 27 Issue 7 December 2002 pp 703-714 Review Article. Applications of inulin and oligofructose in health and nutrition · Narinder Kaur Anil K Gupta · More Details Abstract Fulltext PDF. Inulin and oligofructose belong to ...

  15. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Waleed Gharaibeh. Articles written in Journal of Biosciences. Volume 32 Issue 7 December 2007 pp 1227-1244 Perspectives. Historical evidence for a pre-Columbian presence of Datura in the Old World and implications for a first millennium transfer from the New World.

  16. Microscopy based studies on the interaction of bio-based silver nanoparticles with Bombyx mori Nuclear Polyhedrosis virus.

    Science.gov (United States)

    Tamilselvan, Selvaraj; Ashokkumar, Thirunavukkarasu; Govindaraju, Kasivelu

    2017-04-01

    In the present investigation, silver nanoparticles (AgNPs) interactions with Bombyx mori Nuclear Polyhedrosis virus (BmNPV) were characterized using High-Resolution Scanning Electron Microscopy (HR-SEM), Energy Dispersive X-ray Analysis (EDAX), Transmission Electron Microscopy (TEM), Atomic Force Microcopy (AFM) and Confocal Microscope (CM). HR-SEM study reveals that the biosynthesized AgNPs have interacted with BmNPV and were found on the surface. TEM micrographs of normal and viral polyhedra treated with AgNPs showed that the nanoparticles were accumulated in the membrane and it was noted that some of the AgNPs successfully penetrated the membrane by reaching the capsid of BmNPV. AFM and confocal microscopy studies reveal that the disruption in the shell membrane tends to lose its stability due to exposure of AgNPs to BmNPV. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Using nuclear microscopy to characterize the interaction of textile-used silver nanoparticles with a biological wastewater treatment system

    Science.gov (United States)

    Bento, J. B.; Franca, R. D. G.; Pinheiro, T.; Alves, L. C.; Pinheiro, H. M.; Lourenço, N. D.

    2017-08-01

    The use of engineered nanoparticles in the textile industry has been rapidly increasing but their fate during biological wastewater treatment is largely unknown. The goal of the current study was to characterize the interaction of silver nanoparticles (AgNPs), used in the textile industry, with a biological wastewater treatment system based on aerobic granular sludge (AGS). The exposure tests were performed using a laboratory-scale sequencing batch reactor (SBR) system with AGS. The behavior and fate of textile AgNPs in the AGS system was studied with nuclear microscopy techniques. Elemental maps of AGS samples collected from the SBR showed that AgNPs typically clustered in agglomerates of small dimensions (application of nuclear microscopy for the characterization of the behavior and fate of AgNPs in AGS. The detailed compartmentalization of AgNPs in AGS components obtained with nuclear microscopy provides new and relevant information concerning AgNPs retention. This will be important in biotechnological terms to delineate strategies for AgNPs removal from textile wastewater.

  18. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    College of Horticulture, Shenyang Agricultural University, Shenyang 110866, People's Republic of China; College of Bioscience and Biotechnology, Shenyang Agricultural University, Shenyang 110866, People's Republic of China; Key Laboratory of Protected Horticulture of Ministry of Education, Shenyang Agricultural ...

  19. Division of Agro technology and Biosciences: Past, Present and Future

    International Nuclear Information System (INIS)

    Khairuddin Abdul Rahim

    2012-01-01

    In presenter speech, he outlined several topics regarding development of Agro technology and Biosciences Division from 31 years ago. This division started with Unit Sains Hidupan Liar under PUSPATI in 1981 and change their names to Program Isotop dan Sinaran dalam Biologi dan Pertanian under Nuclear Technology Unit (UTN) (1983). In 1990 their premise change to MINT-Tech Park. This program responsible for conducting research in agro technology using nuclear technology. Several achievements achieved by this division since established. They also succeed in mutating banana namely Novaria banana (1994), Tongkat Ali rice (1990), ground nut (2003), orchids, organic fertilizer and foliage in 2000. The vision of this division are to promote and enhance innovation and applications in nuclear technology to achieve security in food productivity, safety and quality and ecological awareness for economics competitiveness and vibrancy in agrobioindustry and community development. (author)

  20. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Nataša Z Djordjević. Articles written in Journal of Biosciences. Volume 39 Issue 5 December 2014 pp 859-866 Articles. Prooxidative effects of aspartame on antioxidant defense status in erythrocytes of rats · Marko D Prokić Milica G Paunović Miloš M Matić Nataša Z Djordjević Branka ...

  1. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Péter Csermely. Articles written in Journal of Biosciences. Volume 32 Issue 3 April 2007 pp 441-446 Articles. Molecular chaperones: The modular evolution of cellular networks · Tamás Korcsmáros István A Kovács Máté S Szalay Péter Csermely · More Details Abstract Fulltext PDF.

  2. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Branka I Ognjanović. Articles written in Journal of Biosciences. Volume 39 Issue 5 December 2014 pp 859-866 Articles. Prooxidative effects of aspartame on antioxidant defense status in erythrocytes of rats · Marko D Prokić Milica G Paunović Miloš M Matić Nataša Z Djordjević ...

  3. East Midlands healthcare and bioscience sector strategy appendix 1: healthcare and bioscience res implementation plan

    OpenAIRE

    East Midlands Development Agency

    2007-01-01

    The healthcare and bioscience sector is one of four priority sectors identified in the regional economic strategy, A Flourishing Region. This document sets out the implementation plan for maximising the contribution of the healthcare and biosciences sector to the economic development of the East Midlands.

  4. Probing for heavy element impurities in the shell of the Pacific oyster, Crassostrea gigas, with nuclear microscopy

    International Nuclear Information System (INIS)

    Markwitz, A.; Barry, B.; Gauldie, R.W.; Roberts, R.D.

    2003-01-01

    Nuclear microscopy was performed on shells of the Pacific oyster, Crassostrea gigas, to probe for heavy element impurities. For the studies 14 shells from the Auckland and the Marlborough Sounds region were chosen. In sections, the shells appear as opaque with white and grey zones, which are related to alternating layers of calcite and aragonite. Raster scans with 2.5 MeV protons over the sections (scan area 5 x 5 mm) were used in the experiment to measure trace elements in the ppm region using proton induced X-ray spectroscopy. Two dimensional maps and line scans revealed the presence of bromine in all shells investigated. Bromine was found to be related with the pattern of calcium. Hot spots of iron proved to be a common feature in the shells as well. In some shells, copper and zinc were also measured in hot spots of a few micrometers in diameter. Spatially resolved results on the micrometer level indicate the usefulness of nuclear microscopy for the detection of heavy elements in shells of the Pacific oyster

  5. Electron Microscopy Facility for Research and Services in the Malaysian Nuclear Agency towards TSO

    International Nuclear Information System (INIS)

    Nadira Kamarudin; Mohd Bin Harun; Zaiton Selamat

    2011-01-01

    Scanning Electron Microscope FEI-Quanta 400 (SEM) made in the USA was commissioned in late 2003. This equipment is used in many areas of materials science, metallurgy, engineering, electronics, medicine, agriculture, biology and so on. This facility has helped the researchers in conducting research in their respective fields as well have been providing services to agencies, institutions, industries and local industry. Since 2004, there were 81 projects and 5000 samples analyzed using this facility in Malaysian Nuclear Agency, while 23 companies and 900 samples were from various agencies. In addition, revenue derived from these services has able to provide for the maintenance of this equipment. SEM is an important step in the nuclear material testing process. Nuclear material can be inspected for its performance by getting information from its morphology micrograph by using SEM. It opens up a whole new world that is unseen by the naked eye. (author)

  6. Scanning nuclear electric resonance microscopy using quantum-Hall-effect breakdown

    Energy Technology Data Exchange (ETDEWEB)

    Hashimoto, K., E-mail: hashi@m.tohoku.ac.jp; Tomimatsu, T.; Shirai, S.; Taninaka, S.; Nagase, K.; Sato, K.; Hirayama, Y. [Graduate School of Sciences, Tohoku University, Sendai 980-8578 (Japan)

    2016-07-15

    We present a scanning nuclear-spin resonance (NSR) method that incorporates resistive detection with electric-field induced NSR locally excited by a scanning metallic probe. In the quantum-Hall effect breakdown regime, NSR intensity mapping at both the fundamental NSR frequency f{sub 75As} and twice the frequency 2f{sub 75As} demonstrates the capability to probe the distribution of nuclear polarization, particularly in a semiconductor quantum well. We find that f{sub 75As} NSR excitation drives not only local NSR but also spatially overlapped nonlocal NSR, which suppresses the maximum intensity of local NSR, while the 2f{sub 75As} NSR yields purely local excitation conferring a larger intensity.

  7. Chromatin organization at the nuclear periphery as revealed by image analysis of structured illumination microscopy data

    Czech Academy of Sciences Publication Activity Database

    Fišerová, Jindřiška; Efenberková, Michaela; Sieger, T.; Maninová, Miloslava; Uhlířová, Jana; Hozák, Pavel

    2017-01-01

    Roč. 130, č. 12 (2017), s. 2066-2077 ISSN 0021-9533 R&D Projects: GA ČR GJ15-08835Y; GA MŠk(CZ) LM2015062 Institutional support: RVO:68378050 Keywords : Structured illumination * Image analysis * Chromation * Nucleus * Histone modification * Nuclear pore complexes Subject RIV: EB - Genetics ; Molecular Biology OBOR OECD: Cell biology Impact factor: 4.431, year: 2016

  8. Nuclear microscopy as a tool in TiO{sub 2} nanoparticles bioaccumulation studies in aquatic species

    Energy Technology Data Exchange (ETDEWEB)

    Pinheiro, Teresa, E-mail: murmur@itn.pt [IST/ITN, Instituto Superior Técnico, Universidade Técnica de Lisboa and Centro de Física Nuclear, Universidade de Lisboa (Portugal); Moita, Liliana; Silva, Luís; Mendonça, Elsa; Picado, Ana [LNEG, Laboratório Nacional de Energia e Geologia, I.P. Estrada do Paço do Lumiar 22, 1649-038 Lisboa (Portugal)

    2013-07-01

    Engineered Titanium nanoparticles are used for a wide range of applications from coatings, sunscreen cosmetic additives to solar cells or water treatment agents. Inevitably environmental exposure can be expected and data on the ecotoxicological evaluation of nanoparticles are still scarce. The potential effects of nanoparticles of titanium dioxide (TiO{sub 2}) on two model organisms, the water flea, Daphnia magna and the duckweed Lemna minor, were examined in semichronic toxicity tests. Daphnia and Lemna were exposed to TiO{sub 2} nanoparticles (average particle size value of 28 ± 11 nm (n = 42); concentration range, 1.4–25 mg/L) by dietary route and growth in medium containing the nanoparticles of TiO{sub 2}, respectively. Both morphology and microdistribution of Ti in the individuals were examined by nuclear microscopy techniques. A significant amount of TiO{sub 2} was found accumulated in Daphnia exposed to nanoparticles. Nuclear microscopy imaging revealed that Ti was localized only in the digestive tract of the Daphnia, which displayed difficulty in eliminating the nanoparticles from their body. Daphnia showed higher mortality when exposed to higher concentrations of TiO{sub 2} (>10 mg/L). The exposure to TiO{sub 2} nanoparticles above 25 mg/L caused morphological alterations in Lemna. The roots became stiff and fronds colorless. The Ti mapping of cross-sections of roots and fronds showed that Ti was mainly deposited in the epidermis of the fronds and roots, with minor internalization. In summary, exposure of aquatic organisms to TiO{sub 2} nanoparticles may alter the physiology of these organisms at individual and population levels, posing risks to aquatic ecosystems.

  9. High Frequency Acoustic Microscopy for the Determination of Porosity and Young's Modulus in High Burnup Uranium Dioxide Nuclear Fuel

    Science.gov (United States)

    Marchetti, Mara; Laux, Didier; Cappia, Fabiola; Laurie, M.; Van Uffelen, P.; Rondinella, V. V.; Wiss, T.; Despaux, G.

    2016-06-01

    During irradiation UO2 nuclear fuel experiences the development of a non-uniform distribution of porosity which contributes to establish varying mechanical properties along the radius of the pellet. Radial variations of both porosity and elastic properties in high burnup UO2 pellet can be investigated via high frequency acoustic microscopy. For this purpose ultrasound waves are generated by a piezoelectric transducer and focused on the sample, after having travelled through a coupling liquid. The elastic properties of the material are related to the velocity of the generated Rayleigh surface wave (VR). A UO2 pellet with a burnup of 67 GWd/tU was characterized using the acoustic microscope installed in the hot cells of the JRC-ITU at a 90 MHz frequency, with methanol as coupling liquid. VR was measured at different radial positions. A good agreement was found, when comparing the porosity values obtained via acoustic microscopy with those determined using SEM image analysis, especially in the areas close to the centre. In addition, Young's modulus was calculated and its radial profile was correlated to the corresponding burnup profile and to the hardness radial profile data obtained by Vickers micro-indentation.

  10. Dynamics of biosciences regulation and opportunities for biosciences innovation in Africa: exploring regulatory policy brokering

    OpenAIRE

    Kingiri, A.; Hall, A.

    2011-01-01

    Knowledge brokering has been explored in the innovation literature to understand how different innovation tasks are organised toward technological development. This paper reflects upon the role of different organisations as knowledge brokers in regulatory policy processes towards putting biosciences research into use. It identifies a practical function-based typology that describes four categories of policy brokers who perform different tasks, with the potential to impact biosciences regulato...

  11. Environmental Biosciences Program Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2006-10-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this cooperative agreement can be forwarded to Dr. Lawrence C. Mohr in the EBP office of the Medical University of South Carolina at (843) 792-1532.

  12. Environmental Biosciences Program Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2007-07-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the DOE. Plans for restructuring the performance schedule of the trichloroethylene projects have been submitted to the department. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this

  13. Environmental Biosciences Program Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2008-01-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the DOE. Plans for restructuring the performance schedule of the trichloroethylene projects have been submitted to the department. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  14. Environmental Biosciences First Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2003-09-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risk issues. These initiatives are consistent with the Medical University's role as a comprehensive state-supported health sciences institution and the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable the Medical University to be a national resource for the scientific investigation of environmental health issues. EBP's success in convening worldwide scientific expertise is due in part to the inherent credibility the Medical University brings to the process of addressing these complex issues. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), asbestos and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  15. Neutron irradiation damage of nuclear graphite studied by high-resolution transmission electron microscopy and Raman spectroscopy

    Science.gov (United States)

    Krishna, R.; Jones, A. N.; McDermott, L.; Marsden, B. J.

    2015-12-01

    Nuclear graphite components are produced from polycrystalline artificial graphite manufacture from a binder and filler coke with approximately 20% porosity. During the operational lifetime, nuclear graphite moderator components are subjected to fast neutron irradiation which contributes to the change of material and physical properties such as thermal expansion co-efficient, young's modulus and dimensional change. These changes are directly driven by irradiation-induced changes to the crystal structure as reflected through the bulk microstructure. It is therefore of critical importance that these irradiation changes and there implication on component property changes are fully understood. This work examines a range of irradiated graphite samples removed from the British Experimental Pile Zero (BEPO) reactor; a low temperature, low fluence, air-cooled Materials Test Reactor which operated in the UK. Raman spectroscopy and high-resolution transmission electron microscopy (HRTEM) have been employed to characterise the effect of increased irradiation fluence on graphite microstructure and understand low temperature irradiation damage processes. HRTEM confirms the structural damage of the crystal lattice caused by irradiation attributed to a high number of defects generation with the accumulation of dislocation interactions at nano-scale range. Irradiation-induced crystal defects, lattice parameters and crystallite size compared to virgin nuclear graphite are characterised using selected area diffraction (SAD) patterns in TEM and Raman Spectroscopy. The consolidated 'D'peak in the Raman spectra confirms the formation of in-plane point defects and reflected as disordered regions in the lattice. The reduced intensity and broadened peaks of 'G' and 'D' in the Raman and HRTEM results confirm the appearance of turbulence and disordering of the basal planes whilst maintaining their coherent layered graphite structure.

  16. Genotoxicity of non-alcoholic mouth rinses: A micronucleus and nuclear abnormalities study with fluorescent microscopy.

    Science.gov (United States)

    Durbakula, Karteek; Prabhu, Vishnudas; Jose, Maji

    2017-12-15

    The aim of the present study was to evaluate the genotoxicity of non-alcoholic mouth rinses on buccal epithelial cells using a micronucleus test. A total of 105 patients were selected and randomly divided into five groups. Four different mouth rinses and normal saline were given for 2 weeks' duration, and cytological smears were collected before and after exposure. These smears were subjected to micronucleus (MN) and other nuclear abnormalities (ONA) tests using acridine orange stain, and their frequencies were obtained in 500 buccal epithelial cells. The statistical analysis included mean, χ 2 -test, analysis of variance, and post-hoc analysis by Bonferroni test. Micronucleated cells (P < .00) and MN (P < .00) were higher in individuals exposed to chlorhexidine (CHX), followed by chlorine dioxide (ClO 2 ), potassium nitrate (KNO 3 ), and sodium fluoride (NaF), amine fluoride (AmF), and normal saline. ONA were greater (P < .00) in individuals exposed to CHX, followed by ClO 2 , AmF, KNO 3 , and NaF and normal saline. Overall, the results showed that genotoxic damage was greater in the case of CHX, followed by ClO 2 , KNO 3 , and NaF, AmF, and normal saline. Chronic exposure to mouth rinses can cause genotoxic damage to buccal epithelial cells. Long-term injudicious and inadvertent use of mouth rinses should be discouraged. © 2017 John Wiley & Sons Australia, Ltd.

  17. Comparative study between reconstructed and native human epidermis using nuclear microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Ynsa, M.D. [Centre d' Etudes Nucleaires de Bordeaux-Gradignan, IN2P3-CNRS/Unite Interface Physique-Biologie, BP 120, Le Haut Vigneau, 33175 Gradignan Cedex (France)]. E-mail: ynsa@cenbg.in2p3.fr; Gontier, E. [Centre d' Etudes Nucleaires de Bordeaux-Gradignan, IN2P3-CNRS/Unite Interface Physique-Biologie, BP 120, Le Haut Vigneau, 33175 Gradignan Cedex (France); Mavon, A. [Institut de Recherche Pierre FABRE, Castanet Tolosan (France); Moretto, P. [Centre d' Etudes Nucleaires de Bordeaux-Gradignan, IN2P3-CNRS/Unite Interface Physique-Biologie, BP 120, Le Haut Vigneau, 33175 Gradignan Cedex (France); Rosdy, M. [SkinEthic Laboratories, 45 rue St. Philippe, 06000 Nice (France)

    2006-08-15

    The physiological status of native skin is suffering from large inter-individual variations, especially in terms of inorganic ions content. For this reason, together with the advent of ethic laws on animal experimentation, reconstructed skin or epidermis models are extensively employed nowadays in penetration studies for cosmetic or pharmacological applications. It has been already verified that reconstructed human epidermis (RHE) has similar physiological mechanisms to native human skin, but until now, there are few studies where the elemental concentrations of both skins, reconstructed and native, are compared. In this work, freeze-dried thin sections of human native skin obtained from surgery have been characterized using PIXE, RBS and STIM at the CENBG nuclear microprobe. RHE samples were treated and analyzed in the same conditions for comparison. The combination of the different imaging and analysis techniques made possible a clear delimitation and identification of skin ultrastructure. The elemental concentrations of P, S, Cl, K and Ca were measured in the different strata. For both skins, concentrations have been compared and significant differences in terms of elemental concentrations have been determined using statistical approaches. Similar physiological characteristics were pointed out in both skin models, in particular the Ca gradient presumably involved in the regulation of the barrier effect.

  18. Comparative study between reconstructed and native human epidermis using nuclear microscopy

    International Nuclear Information System (INIS)

    Ynsa, M.D.; Gontier, E.; Mavon, A.; Moretto, P.; Rosdy, M.

    2006-01-01

    The physiological status of native skin is suffering from large inter-individual variations, especially in terms of inorganic ions content. For this reason, together with the advent of ethic laws on animal experimentation, reconstructed skin or epidermis models are extensively employed nowadays in penetration studies for cosmetic or pharmacological applications. It has been already verified that reconstructed human epidermis (RHE) has similar physiological mechanisms to native human skin, but until now, there are few studies where the elemental concentrations of both skins, reconstructed and native, are compared. In this work, freeze-dried thin sections of human native skin obtained from surgery have been characterized using PIXE, RBS and STIM at the CENBG nuclear microprobe. RHE samples were treated and analyzed in the same conditions for comparison. The combination of the different imaging and analysis techniques made possible a clear delimitation and identification of skin ultrastructure. The elemental concentrations of P, S, Cl, K and Ca were measured in the different strata. For both skins, concentrations have been compared and significant differences in terms of elemental concentrations have been determined using statistical approaches. Similar physiological characteristics were pointed out in both skin models, in particular the Ca gradient presumably involved in the regulation of the barrier effect

  19. Comparative study between reconstructed and native human epidermis using nuclear microscopy

    Science.gov (United States)

    Ynsa, M. D.; Gontier, E.; Mavon, A.; Moretto, P.; Rosdy, M.

    2006-08-01

    The physiological status of native skin is suffering from large inter-individual variations, especially in terms of inorganic ions content. For this reason, together with the advent of ethic laws on animal experimentation, reconstructed skin or epidermis models are extensively employed nowadays in penetration studies for cosmetic or pharmacological applications. It has been already verified that reconstructed human epidermis (RHE) has similar physiological mechanisms to native human skin, but until now, there are few studies where the elemental concentrations of both skins, reconstructed and native, are compared. In this work, freeze-dried thin sections of human native skin obtained from surgery have been characterized using PIXE, RBS and STIM at the CENBG nuclear microprobe. RHE samples were treated and analyzed in the same conditions for comparison. The combination of the different imaging and analysis techniques made possible a clear delimitation and identification of skin ultrastructure. The elemental concentrations of P, S, Cl, K and Ca were measured in the different strata. For both skins, concentrations have been compared and significant differences in terms of elemental concentrations have been determined using statistical approaches. Similar physiological characteristics were pointed out in both skin models, in particular the Ca gradient presumably involved in the regulation of the barrier effect.

  20. Towards in vivo nuclear microscopy: iodine-125 imaging in mice using micro-pinholes

    International Nuclear Information System (INIS)

    Beekman, Freek J.; McElroy, David P.; Hoffman, Edward J.; Berger, Frank; Gambhir, Sanjiv S.; Cherry, Simon R.

    2002-01-01

    Position-sensitive gamma-radiation detectors equipped with collimators have been used for in vivo imaging of the distribution of radiolabelled molecules in laboratory animals and humans for several decades. To date, the best image resolution achieved in a rodent is on the order of 1 mm. Here we demonstrate how a basic and compact gamma camera can be constructed for in vivo radionuclide imaging in small animals, at much higher spatial resolution. Resolution improvements were obtained by combining dense, shaped, micro-pinhole apertures with iodine-125, an isotope with low energy emissions, ease of incorporation into a wide range of molecules, and straightforward translation into the clinic via other isotopes of iodine that are suitable for nuclear medicine imaging. 125 I images of test distributions and a mouse thyroid have been obtained at a resolution of as high as 200 μm using this simple bench-top camera. Possible future applications and extension to ultra-high-resolution emission tomography are discussed. (orig.)

  1. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2007-02-09

    Feb 9, 2007 ... Home; Journals; Journal of Biosciences; Volume 32; Issue 2. What history tells us VIII. The progressive construction of a mechanism for prion diseases. Michel Morange. Series Volume 32 Issue 2 March 2007 pp 223-227. Fulltext. Click here to view fulltext PDF. Permanent link:

  2. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 42; Issue 1. What history tells us XLII. A 'new' view of proteins. MICHEL MORANGE. Series Volume 42 Issue 1 March 2017 pp 11-14. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/jbsc/042/01/0011-0014. Keywords. Allostery ...

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    Indian Academy of Sciences (India)

    2008-10-15

    Oct 15, 2008 ... Home; Journals; Journal of Biosciences; Volume 33; Issue 4. Combating emerging infectious diseases in India: Orchestrating a symphony. Lalit Kant. Volume 33 Issue 4 November 2008 pp 425-427. Fulltext. Click here to view fulltext PDF. Permanent link:

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    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 25; Issue 3. Patterns of replication in the neo-sex ... H A Ranganath. Articles Volume 25 Issue 3 September 2000 pp 229-234 ... H A Ranganath1. Drosophila Stock Centre, Department of Studies in Zoology, University of Mysore, Manasagangotri, Mysore 570 006, India ...

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    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 33; Issue 4. Issue front cover thumbnail. Volume 33, Issue 4. November 2008, pages 423-628. Special Issue on Emerging and Re-emerging Infections. pp 423-424. Foreword · C C Kartha U C Chaturvedi · More Details Fulltext PDF. pp 425-427. Combating emerging ...

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    Home; Journals; Journal of Biosciences; Volume 34; Issue 5. Issue front cover thumbnail. Volume 34, Issue 5. November 2009, pages 647-823. Special Issue - India's fossil biota: Current perspectives and emerging approaches. pp 647-648. Foreword · Sunil Bajpai Ashok Sahni · More Details Fulltext PDF. pp 649-659 ...

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    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 30; Issue 1. Issue front cover thumbnail. Volume 30, Issue 1. February 2005, pages 1-142. Special Issue on Genetic Determinism. pp 1-2. Foreword · Vidyanand Nanjundiah Stuart A Newman Scott F Gilbert · More Details Fulltext PDF. pp 3-10. The century beyond the gene.

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    Home; Journals; Journal of Biosciences; Volume 34; Issue 4. Issue front cover ... pp 523-528 Articles. Human pancreatic islet progenitor cells demonstrate phenotypic plasticity in vitro ... Cell state switching factors and dynamical patterning modules: complementary mediators of plasticity in development and evolution.

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    Indian Academy of Sciences (India)

    Articles written in Journal of Biosciences. Volume 27 Issue 5 September 2002 pp 479-487 Articles. Dynamic expression ... A conditional Orco requirement in the somatic cyst cells for maintaining spermatids in a tight bundle in Drosophila testis · Pankaj Dubey Prakash Joti Krishanu Ray · More Details Abstract Fulltext PDF.

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    Home; Journals; Journal of Biosciences; Volume 26; Issue 4. Issue front cover thumbnail. Volume 26, Issue 4. November 2001, pages 390a-545. Population of India .... Increasing population and declining biological resources in the context of global change and globalization ... Prehistoric human colonization of India.

  11. Journal of Biosciences | Indian Academy of Sciences

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    2009-05-18

    May 18, 2009 ... Home; Journals; Journal of Biosciences; Volume 34; Issue 2. Clipboard: Snakes and ladders: the ups and downs of animal segmentation. Ramray Bhat Stuart A Newman. Volume 34 Issue 2 June 2009 pp 163-166. Fulltext. Click here to view fulltext PDF. Permanent link:

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    2008-01-31

    Jan 31, 2008 ... Home; Journals; Journal of Biosciences; Volume 33; Issue 1. Biological time is fractal: Early events reverberate over a life time. David Lloyd. Perspectives Volume 33 Issue 1 March 2008 pp 9-19. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/jbsc/033/01/0009- ...

  13. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences; Volume 26; Issue 4. Is there a role for contraceptive vaccines in fertility control? A Jagannadha Rao. Volume 26 Issue 4 November 2001 pp 425-427. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/jbsc/026/04/0425-0427. Keywords. Fertility ...

  14. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences; Volume 28; Issue 4. Density-dependent growth and metamorphosis in the larval bronze frog Rana temporalis is influenced by genetic relatedness of the cohort. S Girish S K Saidapur. Articles Volume 28 Issue 4 June 2003 pp 489-496 ...

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    Home; Journals; Journal of Biosciences; Volume 27; Issue 1. Issue front cover thumbnail. Volume 27, Issue 1. February 2002, pages a-70. Genome Analysis. pp a-a. Preface ... Comparative genomics using data mining tools ... Triplet repeat DNA structures and human genetic disease: dynamic mutations from dynamic DNA.

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    2011-03-14

    Mar 14, 2011 ... Home; Journals; Journal of Biosciences; Volume 36; Issue 1. Clipboard: New paradigm for ATP synthesis and consumption. C Channakeshava. Volume 36 Issue 1 March 2011 pp 3-4. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/jbsc/036/01/0003-0004 ...

  17. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences; Volume 35; Issue 2. Issue front cover thumbnail. Volume 35, Issue 2. June 2010, pages 163-325. pp 163-165. Clipboard: Heat shock protein 90: a capacitor or a mutator? Ritwick Sawarkar Renato Paro · More Details Fulltext PDF. pp 167-169. Clipboard: The small subunit of geranyl ...

  18. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences; Volume 41; Issue 4. Issue front cover thumbnail. Volume 41, Issue 4. December 2016, pages 563-805. pp 563-567 COMMENTARY. The Nobel Prize for understanding autophagy, a cellular mechanism of waste disposal that keeps us healthy · MEGHA BANSAL GHANSHYAM ...

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    Home; Journals; Journal of Biosciences; Volume 32; Issue 2. Heterotrophic ... Articles Volume 32 Issue 2 March 2007 pp 363-374 ... Examination of the correlation between mean heterotrophic bacterial cell size and environmental variables showed four correlations in the river Arkavathy and two in the river Shimsha.

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    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 36; Issue 4. Issue front cover thumbnail. Volume 36, Issue 4. September 2011, pages 555-748. pp 555-557. Clipboard: Controversy over the report on a bacterium that feeds on arsenic · Dipanwita Sengupta Madhab K Chattopadhyay · More Details Fulltext PDF. pp 559-561.

  1. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences; Volume 27; Issue 1. Issue front cover thumbnail. Volume 27, Issue 1. February 2002, pages a-70. Genome Analysis. pp a-a. Preface · Alok Bhattacharya · More Details Fulltext PDF. pp 1-6. SWORDS: A statistical tool for analysing large DNA sequences · Probal Chaudhuri Sandip Das.

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    Home; Journals; Journal of Biosciences; Volume 32; Issue 2. Issue front cover thumbnail. Volume 32, Issue 2. March 2007, pages 181-428. pp 181-182 Articles. Clipboard: Negative databases · Jayant R Haritsa · More Details Fulltext PDF. pp 183-184. Commentary: Who really wants to save the apes? Jonathan Marks.

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    Home; Journals; Journal of Biosciences; Volume 31; Issue 5. Combinative effects of a bacterial type-III effector and a biocontrol bacterium on rice growth and disease resistance. Haiying Ren Ganyu Gu Juying Long Qian Yin Tingquan Wu Tao Song Shujian Zhang Zhiyi Chen Hansong Dong. Reviews Volume 31 Issue 5 ...

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    Home; Journals; Journal of Biosciences; Volume 29; Issue 1. Studies on middle silkgland proteins of cocoon colour sex-limited silkworm (Bombyx mori L.) using two-dimensional polyacrylamide gel electrophoresis. Yuan-Xiang Jin Yu-Yin Chen Meng-Kui Xu Yong-Huang Jiang. Articles Volume 29 Issue 1 March 2004 pp 45- ...

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    Home; Journals; Journal of Biosciences; Volume 36; Issue 4. Eu-Detect: An algorithm for detecting eukaryotic sequences in metagenomic data sets. Monzoorul Haque Mohammed Sudha Chadaram Dinakar Dinakar Komanduri Tarini Shankar Ghosh Sharmila S Mande. Articles Volume 36 Issue 4 September 2011 pp 709- ...

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    Home; Journals; Journal of Biosciences; Volume 25; Issue 1. Avirulent mutants of Macrophomina phaseolina and Aspergillus fumigatus initiate infection in Phaseolus mungo in the presence of phaseo-linone; levamisole gives protection. Suchandra Sett Santosh K Mishra Kazia I Siddiqui. Articles Volume 25 Issue 1 March ...

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    Mohinish Shukla1. Cognitive Neuroscience Sector, International School for Advanced Studies (SISSA), Via Beirut 9, 34014 Trieste, Italy. Journal of Biosciences. Current Issue : Vol. 43, Issue 1 · Current Issue Volume 43 | Issue 1. March 2018. Home · Volumes & Issues · Special Issues · Forthcoming Articles · Gallery of Cover ...

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    Home; Journals; Journal of Biosciences; Volume 42; Issue 2. Issue front cover thumbnail. Volume 42, Issue 2. June 2017, pages 209-353. pp 209-218 Article. Genetic diagnosis of a Chinese multiple endocrine neoplasia type 2A family through whole genome sequencing · ZHEN-FANG DU PENG-FEI LI JIAN-QIANG ZHAO ...

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    Home; Journals; Journal of Biosciences; Volume 40; Issue 3. A rapidly progressing, deadly disease of Actias selene (Indianmoonmoth) larvae associated with a mixed bacterial and baculoviral infection. Marta A Skowron Beata Guzow-Krzemińska Sylwia Barańska Paulina Jędrak Grzegorz Węgrzyn. Articles Volume 40 ...

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    Home; Journals; Journal of Biosciences; Volume 31; Issue 1. Issue front cover thumbnail. Volume 31, Issue 1. March 2006, pages 1-176e. pp 1-2. Clipboard: Ancient Indian roots? Denise R Carvalho-Silva Tatiana Zerjal Chris Tyler-Smith · More Details Fulltext PDF. pp 3-4. Commentary: Magic with moulds: Meiotic and ...

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    Home; Journals; Journal of Biosciences; Volume 32; Issue 3. Issue front cover thumbnail. Volume 32, Issue 3. April 2007, pages 429-628. Special issue on Environmental factors, cellular stress and evolution. pp 429-431. Foreword · Subhash C Lakhotia · More Details Fulltext PDF. pp 433-440 Articles. Key issues in ...

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    Home; Journals; Journal of Biosciences; Volume 34; Issue 6. Issue front cover thumbnail. Volume 34, Issue 6. December 2009, pages 825-1003. pp 825-827. Clipboard: From the RNA world to the DNA-protein world: clues to the origin and early evolution of life in the ribosome · Enrique Meléndez-Hevia · More Details ...

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    Home; Journals; Journal of Biosciences; Volume 41; Issue 3. Diazinon degradation by a novel strain Ralstonia sp. DI-3 and X-ray crystal structure determination of the metabolite of diazinon. GUANGLI WANG YUAN LIU. Volume 41 Issue 3 September 2016 pp 359-366 ...

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    Home; Journals; Journal of Biosciences; Volume 28; Issue 1. Issue front cover thumbnail. Volume 28, Issue 1. February 2003, pages a-134. Oxygen/Nitrogen Radicals: Cell Injury and Disease. pp a-a. Preface · Val Vallyathan Rajiv K Saxena Vince Castranova · More Details Fulltext PDF. pp 1-5. The effect of Gongronema ...

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    Home; Journals; Journal of Biosciences; Volume 30; Issue 4. Amelioration of altered antioxidant status and membrane linked functions by vanadium and Trigonella in alloxan diabetic rat brains. Mohammad Rizwan Siddiqui Asia Taha K Moorthy Mohd Ejaz Hussain S F Basir Najma Zaheer Baquer. Articles Volume 30 Issue ...

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    ... Journals; Journal of Biosciences; Volume 35; Issue 1. Transgene transmission in South American catfish (Rhamdia quelen) larvae by sperm-mediated gene transfer. Tiago Collares Vinicius Farias Campos Fabiana Kömmling Seixas Paulo V Cavalcanti Odir A Dellagostin Heden Luiz M Moreira João Carlos Deschamps.

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    Home; Journals; Journal of Biosciences; Volume 36; Issue 3. Issue front cover thumbnail. Volume 36, Issue 3. August 2011, pages 397-553. Special Issue. pp 397-398. Editorial · J K Roy · More Details Fulltext PDF. pp 399-423 Articles. Forty years of the 93D puff of Drosophila melanogaster · Subhash C Lakhotia.

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    Home; Journals; Journal of Biosciences; Volume 33; Issue 3. Issue front cover thumbnail. Volume 33, Issue 3. September 2008, pages 309-421. pp 309-311. Clipboard: Functional embryo sac formation in Arabidopsis without meiosis – one step towards asexual seed formation (apomixis) in crops? Anna M G Koltunow ...

  19. Journal of Biosciences | Indian Academy of Sciences

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    T GUEVARA-FIGUEROA. Articles written in Journal of Biosciences. Volume 42 Issue 2 June 2017 pp 245-250 Article. Effect of foliar application of salicylic acid, hydrogen peroxide and a xyloglucan oligosaccharide on capsiate content and gene expression associatedwith capsinoids synthesis in Capsicum annuum L.

  20. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences; Volume 40; Issue 4. Graph-based unsupervised feature selection and multiview clustering for microarray data. Tripti Swarnkar Pabitra Mitra ... Keywords. Biological functional enrichment; clustering; explorative data analysis; feature selection; gene selection; graph-based learning.

  1. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences; Volume 25; Issue 1. Clipboard: Transfer of learning across the somatosensory cortex. Mohinish Shukla. Volume 25 Issue 1 March 2000 pp 5-6. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/jbsc/025/01/0005-0006. Author Affiliations.

  2. Journal of Biosciences | Indian Academy of Sciences

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    Alok Bhattacharya1. School of Life Sciences and Information Technology, Jawaharlal Nehru University, New Delhi 110 007, India. Journal of Biosciences. Current Issue : Vol. 43, Issue 1 · Current Issue Volume 43 | Issue 1. March 2018. Home · Volumes & Issues · Special Issues · Forthcoming Articles · Gallery of Cover Art ...

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    Home; Journals; Journal of Biosciences; Volume 41; Issue 2. Toward the 'new century' of handedness in biology: In commemoration of the 100th anniversary of the birth of Francis Crick. Koji Tamura. Clipboard Volume 41 Issue 2 June 2016 pp 169-170 ...

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    Indian Academy of Sciences (India)

    The submission of a paper by a set of authors will be held to imply that it represents the results of their original research not previously published; that it is not under consideration for publication elsewhere; and that if accepted for Journal of Biosciences it will not be published elsewhere. Please read the PACT FORM before ...

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    Home; Journals; Journal of Biosciences; Volume 33; Issue 5. Issue front cover thumbnail. Volume 33, Issue 5. December 2008, pages 629-805. pp 629-630. Clipboard: Monitoring the energy status of a living organism in real time · Athel Cornish-Bowden · More Details Fulltext PDF. pp 631-633. Clipboard: The Indian genetic ...

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    Articles written in Journal of Biosciences. Volume 26 Issue 5 December 2001 pp 547-547. Clipboard: New challenges in human genetics: modifier genes · B J Rao · More Details Fulltext PDF. Volume 28 Issue 5 September 2003 pp 533-534. Clipboard: Human Y-chromosome: a hall of mirrors · B J Rao Kundan Sengupta.

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    Home; Journals; Journal of Biosciences; Volume 28; Issue 3. Issue front cover thumbnail. Volume 28, Issue 3. April 2003, pages 248-358. Viral Evasion of Host Responses. pp 248-248. Preface · Shahid Jameel · More Details Fulltext PDF. pp 249-264 Articles. Viral mimicry of the complement system · John Bernet Jayati ...

  8. Journal of Biosciences | Indian Academy of Sciences

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    XIAOQING SUN. Articles written in Journal of Biosciences. Volume 41 Issue 2 June 2016 pp 229-236 Article. Silencing of HMGA2 promotes apoptosis and inhibits migration and invasion of prostate cancer cells · Zhan Shi Ding Wu Run Tang Xiang Li Renfu Chen Song Xue Chengjing Zhang Xiaoqing Sun · More Details ...

  9. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2009-12-09

    Dec 9, 2009 ... Home; Journals; Journal of Biosciences; Volume 34; Issue 6. Commentary: The linguistic history of some Indian domestic plants. Michael Witzel. Volume 34 Issue 6 December 2009 pp 829-833. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/jbsc/034/06/0829- ...

  10. Journal of Biosciences | Indian Academy of Sciences

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    ... Mid Year Meetings · Discussion Meetings · Public Lectures · Lecture Workshops · Refresher Courses · Symposia · Live Streaming. Home; Journals; Journal of Biosciences; Volume 28; Issue 2. Integrative microbiology – the third Golden Age. Moselio Schaechter. Perspectives Volume 28 Issue 2 March 2003 pp 149-154 ...

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    Home; Journals; Journal of Biosciences; Volume 31; Issue 1. Looking back, looking ... Review Volume 31 Issue 1 March 2006 pp 167-176 ... Bhardwaj1. ESRC Centre for Economic and Social Aspects of Genomics (CESAGen), Institute of Advanced Studies (IAS), County South, Lancaster University, Lancaster LA1 4YD, UK ...

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    Home; Journals; Journal of Biosciences; Volume 40; Issue 5. Comparative sequence analyses of genome and transcriptome reveal novel transcripts and variants in the Asian elephant Elephas maximus. Puli Chandramouli Reddy Ishani Sinha Ashwin Kelkar Farhat Habib Saurabh J Pradhan Raman Sukumar Sanjeev ...

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    Home; Journals; Journal of Biosciences; Volume 29; Issue 1. What impact, if any, has feminism had on science? Evelyn Fox Keller. Perspectives Volume 29 Issue 1 March 2004 pp 7-13. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/jbsc/029/01/0007-0013. Author Affiliations.

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    Home; Journals; Journal of Biosciences; Volume 34; Issue 6. Identification and ... Alignment and phylogenetic analysis indicated that GbAGL2 shared high homology with AG-subfamily genes and belonged to a C-class gene family. DNA gel blot analysis showed that GbAGL2 belonged to a low-copy gene family. Reverse ...

  15. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences; Volume 36; Issue 1. P1 peptidase – a mysterious protein of family Potyviridae. Jana Rohožková Milan Navrátil ... The coding region for P1 peptidase is located at the very beginning of the viral genome of the family Potyviridae. Until recently P1 was thought of as serine peptidase with ...

  16. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 36; Issue 4. RET gene mutations and ... Articles Volume 36 Issue 4 September 2011 pp 603-611 ... Further, 39 family members of seven index cases were analysed, wherein four of the seven index cases showed identical mutations, in 13 of 25 family members. We also ...

  17. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences; Volume 36; Issue 2. Splicing ... Articles Volume 36 Issue 2 June 2011 pp 281-287 ... One proband had mutation at the canonical splice site at +5 position of IVS22, and analysis of the transcripts in this family revealed skipping of exon 22 in three members of this family. In one proband ...

  18. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences; Volume 34; Issue 2 ... Review Volume 34 Issue 2 June 2009 pp 313-320 ... Matrix metalloproteinases (MMPs) are a family of zinc (Zn)-dependent endopeptidases that are collectively capable of cleaving virtually all extracellular matrix (ECM) substrates and play an important role in ...

  19. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 40; Issue 2 ... Articles Volume 40 Issue 2 June 2015 pp 241-255 ... When individual homeobox genes were compared with members of known class or family, we could further classify them into 3 groups, namely, TALE, OTHER and NOVEL classes, but no HOX family was ...

  20. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 42; Issue 1. Diverse roles of WDR5-RbBP5-ASH2L-DPY30 (WRAD) complex in the functions of the SET1 histone methyltransferase family. AAMIR ALI SHWETA TYAGI. Mini-Review Volume 42 Issue 1 ... Keywords. Cell cycle regulation; SET1 family; transcription; WRAD ...

  1. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences; Volume 39; Issue 5. Evolution and expression analysis of the soybean glutamate decarboxylase gene family ... Although plant GAD plays important roles in GABA biosynthesis, our knowledge concerning GAD gene family members and their evolutionary relationship remains limited.

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    Home; Journals; Journal of Biosciences; Volume 39; Issue 3. What history tells us XXXIV. The complex history of the selective model of antibody formation. Michel Morange. Series Volume 39 Issue 3 June 2014 pp 347-350. Fulltext. Click here to view fulltext PDF. Permanent link:

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    2006-05-06

    May 6, 2006 ... Home; Journals; Journal of Biosciences; Volume 31; Issue 2. Kenneth Raper, Elisha Mitchell and Dictyostelium. Eugene R Katz. Perspectives Volume 31 Issue 2 June 2006 pp 195-200. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/jbsc/031/02/0195-0200 ...

  4. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Dang Thanh Hai. Articles written in Journal of Biosciences. Volume 40 Issue 1 March 2015 pp 113-124 Articles. Whole genome analysis of a Vietnamese trio · Dang Thanh Hai Nguyen Dai Thanh Pham Thi Minh Trang Le Si Quang Phan Thi Thu Hang Dang Cao Cuong Hoang Kim Phuc Nguyen Huu Duc Do Duc Dong Bui ...

  5. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 42; Issue 4. Issue front cover thumbnail. Volume 42, Issue 4. December 2017, pages 523-707. pp 523-525 Commentary. Irregular designs and Darwinism in biology: Genomes as the test case · B J RAO · More Details Abstract Fulltext PDF. pp 527-530 Series. What history ...

  6. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2010-11-09

    Nov 9, 2010 ... Home; Journals; Journal of Biosciences; Volume 35; Issue 4. What history tells us XXII. The French neo-Lamarckians. Michel Morange. Series Volume 35 Issue 4 December 2010 pp 515-517. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/jbsc/035/04/0515-0517 ...

  7. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 34; Issue 4. Issue front cover thumbnail. Volume 34, Issue 4. October 2009, pages 493-646. Special issue on Phenotypic and Developmental Plasticity. pp 493-494. Foreword · Vidyanand Nanjundiah Stuart A Newman · More Details Fulltext PDF. pp 495-501 Articles.

  8. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Sanjana Kuruppath. Articles written in Journal of Biosciences. Volume 37 Issue 4 September 2012 pp 581-588. Commentary: Monotremes and marsupials: Comparative models to better understand the function of milk · Sanjana Kuruppath Swathi Bisana Julie A Sharp Christophe Lefevre Satish Kumar Kevin R Nicholas.

  9. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 37; Issue 6. Issue front cover thumbnail. Volume 37, Issue 6. December 2012, pages 921-1121. pp 921-923. Clipboard: Endocannabinoid signalling is required for estrogen-dependent modulation of inhibitory transmission · Liisa A Tremere Raphael Pinaud · More Details ...

  10. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 38; Issue 2. Issue front cover thumbnail. Volume 38, Issue 2. June 2013, pages 181-449. pp 181-187. Commentary: There is no common ground between science and religion · Antonio G Valdecasas Luis Boto Ana Maria Correas · More Details Fulltext PDF. pp 189-199.

  11. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Permanent link: https://www.ias.ac.in/article/fulltext/jbsc/037/04/0581-0588. Keywords. Altricial young; evolution; lactation; mammal; milk; monotreme; platform technologies; proteins; wallaby. Author Affiliations ... Journal of Biosciences | News. Tweets about @iascbng #jbsc. © 2017 Indian Academy of Sciences, Bengaluru.

  12. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 39; Issue 4. Issue front cover thumbnail. Volume 39, Issue 4. September 2014, pages 543-738. pp 543-544. Editorial: Remembering Obaid - One Year Later · Shahid Jameel Utpal Banerjee K VijayRaghavan · More Details Fulltext PDF. pp 545-545. Commentary: Recalling ...

  13. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 40; Issue 5. Issue front cover thumbnail. Volume 40, Issue 5. December 2015, pages 829-968. pp 829-832 Series. What history tells us XXXIX. CRISPR-Cas : From a prokaryotic immune system to a universal genome editing tool · Michel Morange · More Details Fulltext PDF.

  14. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 31; Issue 2. Issue front cover thumbnail. Volume 31, Issue 2. June 2006, pages 177-292. pp 177-179. Clipboard: Simple laboratory tests of ecological theories: what we can learn from them, and when we should be cautious · Mike S Fowler Lasse Ruokolainen · More Details ...

  15. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 37; Issue 4. Changes in membrane lipids and carotenoids during light acclimation in a marine cyanobacterium Synechococcus sp. Olimpio Montero Alberto Sánchez-Guijo Luis M Lubián Gonzalo Martínez-Rodríguez. Articles Volume 37 Issue 4 September 2012 pp 635-645 ...

  16. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 42; Issue 1. Overexpression of hsa-miR-939 follows by NGFR down-regulation and apoptosis reduction. FAHIMEH HOSSEINI AGHDAEI BAHRAM M SOLTANI SADAT DOKANEHIIFARD SEYED JAVAD MOWLA MASOUD SOLEIMANI. Article Volume 42 Issue 1 March 2017 ...

  17. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 32; Issue 5. Issue front cover ... pp 809-825 Articles. Theoretical analysis of noncanonical base pairing interactions in RNA molecules ... pp 851-862 Articles. Identification and annotation of promoter regions in microbial genome sequences on the basis of DNA stability.

  18. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 25; Issue 4. Volume 25, Issue 4. December 2000, pages 315-416. pp 315-316. Clipboard: Alzheimer's disease: amyloid -peptide antibody vaccine as plaque remover · Arun Kumar · More Details Fulltext PDF. pp 317-322. Commentary: His kinase or mine? Histidine kinases ...

  19. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2016-08-26

    Aug 26, 2016 ... Home; Journals; Journal of Biosciences; Search ... part of the email address of all email addresses used by the office of Indian Academy of Sciences, including those of the staff, the journals, various programmes, and Current Science, has changed from 'ias.ernet.in' (or 'academy.ias.ernet.in') to 'ias.ac.in'.

  20. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2005-01-07

    Jan 7, 2005 ... ... Lecture Workshops · Refresher Courses · Symposia · Live Streaming. Home; Journals; Journal of Biosciences; Volume 30; Issue 1. Mechanisms for the environmental regulation of gene expression: Ecological aspects of animal development. Scott F Gilbert. Volume 30 Issue 1 February 2005 pp 65-74 ...

  1. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 28; Issue 4. Hypervariable spacer regions are good sites for developing specific PCR-RFLP markers and PCR primers for screening actinorhizal symbionts. Rajani Varghese Vineeta S Chauhan Arvind K Misra. Articles Volume 28 Issue 4 June 2003 pp 437-442 ...

  2. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 34; Issue 3 .... Single-nucleotide polymorphisms in peroxisome proliferator-activated receptor and their association with plasma levels of resistin and the metabolic ... Association preference and mechanism of kin recognition in tadpoles of the toad Bufo melanostictus.

  3. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2009-08-19

    Aug 19, 2009 ... Home; Journals; Journal of Biosciences; Volume 34; Issue 3. What history tells us XVIII. When functional biologists propose mechanisms of evolution. Michel Morange. Series Volume 34 Issue 3 September 2009 pp 373-376. Fulltext. Click here to view fulltext PDF. Permanent link:

  4. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 27; Issue 6. Issue front cover thumbnail. Volume 27, Issue 6. November 2002, pages 552-627. Special Issue on Suppl. 3: The Biology of Entamoeba histolytica. pp 552-552a. Preface · Anuradha Lohia · More Details Fulltext PDF. pp 553-557 Articles.

  5. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2005-11-23

    Nov 23, 2005 ... Home; Journals; Journal of Biosciences; Volume 30; Issue 5. Commentary: Neuronal survival in epilepsy: to die or not to die? Subramaniam Ganesh Shweta Singh. Volume 30 Issue 5 December 2005 pp 561-566. Fulltext. Click here to view fulltext PDF. Permanent link:

  6. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 40; Issue 4. Protein–Protein interaction site prediction in Homo sapiens and E. coli using an interaction-affinity based membership function in fuzzy SVM. Brijesh Kumar Sriwastava Subhadip Basu Ujjwal Maulik. Articles Volume 40 Issue 4 October 2015 pp 809-818 ...

  7. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2007-06-16

    Jun 16, 2007 ... Home; Journals; Journal of Biosciences; Volume 32; Issue 5. ARC: Automated Resource Classifier for agglomerative functional classification of prokaryotic proteins using annotation texts. Muthiah Gnanamani Naveen Kumar Srinivasan Ramachandran. Articles Volume 32 Issue 5 August 2007 pp 937-945 ...

  8. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 33; Issue 1. Issue front cover thumbnail. Volume 33, Issue 1. March 2008, pages 1-155. pp 1-3. Clipboard: Selecting cells to make cerebral cortex · Yijing Chen David J Price · More Details Fulltext PDF. pp 5-8. Commentary: Sex determination: Are two mechanisms better than ...

  9. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 33; Issue 2. Issue front cover thumbnail. Volume 33, Issue 2. June 2008, pages 157-307. pp 157-158. Clipboard: Recovery from amblyopia in adults via decreased visual cortical inhibition caused by experience in an enriched environment · Liisa A Tremere Raphael Pinaud.

  10. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 26; Issue 4. Issue front cover thumbnail. Volume 26, Issue 4. November 2001, pages 390a-545. Population of India. pp 390a-390a. Preface · Partha P Majumder A Jagannadha Rao · More Details Fulltext PDF. pp 391-405. Current status of fertility control methods in India.

  11. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2009-01-05

    Jan 5, 2009 ... Home; Journals; Journal of Biosciences; Volume 34; Issue 4. Cell state switching factors and dynamical patterning modules: complementary mediators of plasticity in development and evolution. Stuart A Newman Ramray Bhat Nadejda V Mezentseva. Articles Volume 34 Issue 4 October 2009 pp 553-572 ...

  12. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 39; Issue 3. Issue front cover thumbnail. Volume 39, Issue 3. June 2014, pages 333-541. pp 333-337. Clipboard: Biodiversity only makes sense in the light of evolution · R Geeta Lúcia G Lohmann Susana Magallón Daniel P Faith Andrew Hendry Keith Crandall Luc De ...

  13. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 41; Issue 4. Expressions of visual pigments and synaptic proteins in neonatal chick retina exposed to light of variable photoperiods. KUMAR ABHIRAM JHA TAPAS C NAG SHASHI WADHWA TARA SANKAR ROY. ARTICLE Volume 41 Issue 4 December 2016 pp 667-676 ...

  14. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Administration of the various combinations of the antidiabetic compounds to diabetic animals was found to reverse most of the diabetic effects studied at ... School of Life Sciences, Jawaharlal Nehru University, New Delhi 110 067, India; Division of Biosciences, Faculty of Life Sciences, University College London, WC1E 6BT ...

  15. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2007-08-18

    Aug 18, 2007 ... Home; Journals; Journal of Biosciences; Volume 32; Issue 6. Living in a physical world XII. Keeping up upward and down downward. Steven Vogel. Series Volume 32 Issue 6 September 2007 pp 1067-1081. Fulltext. Click here to view fulltext PDF. Permanent link:

  16. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 37; Issue 6. What history tells us XXIX. Transfers from plant biology: From cross protection to RNA interference and DNA vaccination. Michel Morange. Series Volume 37 Issue 6 December 2012 pp 949-952 ...

  17. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 30; Issue 5. Issue front cover thumbnail. Volume 30, Issue 5. December 2005, pages 551-795. pp 551-552. Clipboard: Tumour development due to stroma permissiveness · Edna Cukierman · More Details Fulltext PDF. pp 553-555. Clipboard: Cellular clocks: circadian ...

  18. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 26; Issue 2. The roots of ancient medicine: an historical outline. B V Subbarayappa. Perspectives Volume 26 Issue 2 June 2001 pp 135-143. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/jbsc/026/02/0135-0143. Author Affiliations.

  19. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Information for Authors. Journal of Biosciences. (Manuscripts not conforming to the following specifications will be returned). The submission of a paper by a set of authors will be held to imply that it represents the results of their original research not previously published; that it is not under consideration for publication ...

  20. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 32; Issue 5. Issue front cover thumbnail. Volume 32, Issue 5. August 2007, pages 807-1039. Special Issue - Bioinformatics: From Molecules to Systems. pp 807-807. Foreword · Alok Bhattacharya · More Details Fulltext PDF. pp 809-825 Articles. Theoretical analysis of ...

  1. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 31; Issue 2. Genetic transformation of peanut (Arachis hypogaea L.) using cotyledonary node as explant and a promoterless gus::nptII fusion gene based vector. T Swathi Anuradha S K Jami R S Datla P B Kirti. Articles Volume 31 Issue 2 June 2006 pp 235-246 ...

  2. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 36; Issue 1. Issue front cover thumbnail. Volume 36 ... pp 17-21 Perspectives. The charms of sex chromosomes in snakes · Lalji Singh ... pp 27-35 Brief communication. Lactam nonanic acid, a new substance from Cleome viscosa with allelopathic and antimicrobial properties.

  3. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 40; Issue 3. Issue front cover thumbnail. Volume 40, Issue 3. September 2015, pages 473-666. pp 473-476 Series. What history tells us XXXVIII. Resurrection of a transient forgotten model of gene action · Michel Morange · More Details Fulltext PDF. pp 477-485 Articles.

  4. Cellular distribution of uranium after acute exposure of renal epithelial cells: SEM, TEM and nuclear microscopy analysis

    Energy Technology Data Exchange (ETDEWEB)

    Carriere, Marie [Laboratoire Pierre Suee, CEA-CNRS UMR 9956, CEA/Saclay, 91191 Gif-sur-Yvette (France)]. E-mail: carriere@drecam.cea.fr; Gouget, Barbara [Laboratoire Pierre Suee, CEA-CNRS UMR 9956, CEA/Saclay, 91191 Gif-sur-Yvette (France); Gallien, Jean-Paul [Laboratoire Pierre Suee, CEA-CNRS UMR 9956, CEA/Saclay, 91191 Gif-sur-Yvette (France); Avoscan, Laure [Laboratoire Pierre Suee, CEA-CNRS UMR 9956, CEA/Saclay, 91191 Gif-sur-Yvette (France); Gobin, Renee [Laboratoire d' imagerie cellulaire et moleculaire, DBJC/SBFM/LTMD, CEA/Saclay, 91191 Gif sur Yvette (France); Verbavatz, Jean-Marc [Laboratoire d' imagerie cellulaire et moleculaire, DBJC/SBFM/LTMD, CEA/Saclay, 91191 Gif sur Yvette (France); Khodja, Hicham [Laboratoire Pierre Suee, CEA-CNRS UMR 9956, CEA/Saclay, 91191 Gif-sur-Yvette (France)

    2005-04-01

    The major health effect of uranium exposure has been reported to be chemical kidney toxicity, functional and histological damages being mainly observed in proximal tubule cells. Uranium enters the proximal tubule as uranyl-bicarbonate or uranyl-citrate complexes. The aim of our research is to investigate the mechanisms of uranium toxicity, intracellular accumulation and repartition after acute intoxication of rat renal proximal tubule epithelial cells, as a function of its chemical form. Microscopic observations of renal epithelial cells after acute exposure to uranyl-bicarbonate showing the presence of intracellular precipitates as thin needles of uranyl-phosphate localized in cell lysosomes have been published. However the initial site of precipitates formation has not been identified yet: they could either be formed outside the cells before internalization, or directly inside the cells. Uranium solubility as a function and initial concentration was specified by ICP-MS analysis of culture media. In parallel, uranium uptake and distribution in cell monolayers exposed to U-bicarbonate was investigated by nuclear microprobe analyses. Finally, the presence of uranium precipitates was tested out by scanning electron microscopic observations (SEM), while extracellular and/or intracellular precipitates were observed on thin sections of cells by transmission electron microscopy (TEM)

  5. Environmental Biosciences Program Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2009-01-30

    Current research projects have focused Environmental Biosciences Program (EBP) talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene, low-dose ionizing radiation (gamma and neutron) and alpha radiation from plutonium. Trichloroethylene research has been conducted as a joint collaborative effort with the University of Georgia. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the United States Department of Energy (DOE). Laboratory work has been completed on several trichloroethylene risk assessment projects, and these projects have been brought to a close. Plans for restructuring the performance schedule of the remaining trichloroethylene projects have been submitted to the department. A comprehensive manuscript on the scientific basis of trichloroethylene risk assessment is in preparation. Work on the low-dose radiation risk assessment projects is also progressing at a slowed rate as a result of funding uncertainties. It has been necessary to restructure the proponency and performance schedule of these projects, with the project on Low-Dose Radiation: Epidemiology Risk Models transferred to DOE Office of Science proponency under a separate funding instrument. Research on this project will continue under the provisions of the DOE Office of Science funding instrument, with progress reported in accordance with the requirements of that funding instrument. Progress on that project will no longer be reported in quarterly reports for DE-FC09-02CH11109. Following a meeting at the Savannah River Site on May 8, 2008, a plan was submitted for development of an epidemiological cohort study and prospective medical surveillance system for the assessment of disease rates among workers at the Savannah River

  6. Neuroscience meets salivary bioscience: An integrative perspective.

    Science.gov (United States)

    Segal, Sabrina K

    2016-04-01

    Advances in salivary bioscience enable unique opportunities to explore individual differences in biological mechanisms related to learning and memory, psychiatric disorders, and more recently neurodegenerative diseases, neurotrauma/stroke, pain, and sleep. Sampling oral fluid is not only minimally invasive, but specimens can be collected easily and quickly in clinical and field settings. Salivary analytes allow neuroscientists to index endocrine, autonomic, immune, metabolic, and inflammatory processes within close proximity of discrete behavioral, biological, and social events, which is particularly important to advancing our understanding of human neuroscience. This review provides an update on the advances in salivary bioscience for specialty fields within neuroscience, presents novel salivary analytes of interest to neuroscience and the status of their development, and outlines a procedural framework to facilitate integration of these concepts and methods into neuroscience. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  7. Object-oriented programming for the biosciences.

    Science.gov (United States)

    Wiechert, W; Joksch, B; Wittig, R; Hartbrich, A; Höner, T; Möllney, M

    1995-10-01

    The development of software systems for the biosciences is always closely connected to experimental practice. Programs must be able to handle the inherent complexity and heterogeneous structure of biological systems in combination with the measuring equipment. Moreover, a high degree of flexibility is required to treat rapidly changing experimental conditions. Object-oriented methodology seems to be well suited for this purpose. It enables an evolutionary approach to software development that still maintains a high degree of modularity. This paper presents experience with object-oriented technology gathered during several years of programming in the fields of bioprocess development and metabolic engineering. It concentrates on the aspects of experimental support, data analysis, interaction and visualization. Several examples are presented and discussed in the general context of the experimental cycle of knowledge acquisition, thus pointing out the benefits and problems of object-oriented technology in the specific application field of the biosciences. Finally, some strategies for future development are described.

  8. Nitrogen-15 reference book: medicine and biosciences

    International Nuclear Information System (INIS)

    Faust, H.

    1983-04-01

    A comprehensive bibliography on the application of the stable nitrogen isotope 15 N in medicine, animal nutrition and physiology, biosciences, and related disciplines is presented. The literature pertaining to this paper covers the period from 1977 to 1981. The references are completed by an index of all authors and a subject index with special emphasis to the used organisms, labelled compounds, and tracer techniques, respectively. (author)

  9. Developing Research Capabilities in Energy Biosciences

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Donald D.

    2008-01-01

    Scientists founded the Life Sciences Research Foundation (LSRF) in 1983 as a non-profit pass through foundation that awards post doctoral fellowships in all areas of the life sciences. LSRF scientists review hundreds of applications each year from PhDs seeking support. For example this year, our 26th, we received 800 applications and our peer review committee will choose about 50 finalists who are eligible for these awards. We have no endowment so we solicit sponsors each year. The fellowships are sponsored by research oriented companies, foundations, philanthropists, the Howard Hughes Medical Institute, and other organizations who believe in the value of awarding fellowships to the best and the brightest young scientists. Our web site has a complete listing of all details about LSRF (http://www.lsrf.org/). In the late 1980s the Division of Bioscience in the Office of Basic Energy Science, a granting agency of the Department of Energy, joined this partnership. Bioscience's mandate was to support non-medical microbiology and plant sciences. LSRF received a series of 5 year grants from DOE to award fellowships to our top applicants in these fields of research. We began to support DOE-Energy Bioscience post doctoral fellows in 1989. From 1989 through 2004 when DOE funding ended our partnership awarded 41 DOE-Energy Bioscience Fellows of the Life Sciences Research Foundation. Each of these was a three year fellowship. DOE-Energy Biosciences was well matched with LSRF. Our extensive peer review screened applicants in all areas of the life sciences. Most LSRF sponsors are interested in supporting fellows who work on diseases. At the time that we began our partnership with DOE we had no sponsors willing to support plant biology and non medical microbiology. For 15 years DOE played a major role in the training of the very best young scientists in these important fields of research simply through its support of LSRF post doctoral fellows. Young scientists interested in

  10. Localization microscopy of DNA in situ using Vybrant{sup ®} DyeCycle™ Violet fluorescent probe: A new approach to study nuclear nanostructure at single molecule resolution

    Energy Technology Data Exchange (ETDEWEB)

    Żurek-Biesiada, Dominika [Laboratory of Cell Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków (Poland); Szczurek, Aleksander T. [Institute of Molecular Biology (IMB), Ackermannweg 4, 55128 Mainz (Germany); Prakash, Kirti [Institute of Molecular Biology (IMB), Ackermannweg 4, 55128 Mainz (Germany); Institute for Pharmacy and Molecular Biotechnology (IPMB), University of Heidelberg, Im Neuenheimer Feld 364, D-69120 Heidelberg (Germany); Mohana, Giriram K. [Institute of Molecular Biology (IMB), Ackermannweg 4, 55128 Mainz (Germany); Lee, Hyun-Keun [Institute of Molecular Biology (IMB), Ackermannweg 4, 55128 Mainz (Germany); Department of Physics, University of Mainz (JGU), Staudingerweg 7, 55128 Mainz (Germany); Roignant, Jean-Yves [Institute of Molecular Biology (IMB), Ackermannweg 4, 55128 Mainz (Germany); Birk, Udo J. [Institute of Molecular Biology (IMB), Ackermannweg 4, 55128 Mainz (Germany); Department of Physics, University of Mainz (JGU), Staudingerweg 7, 55128 Mainz (Germany); Dobrucki, Jurek W., E-mail: jerzy.dobrucki@uj.edu.pl [Laboratory of Cell Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków (Poland); Cremer, Christoph, E-mail: c.cremer@imb-mainz.de [Institute of Molecular Biology (IMB), Ackermannweg 4, 55128 Mainz (Germany); Institute for Pharmacy and Molecular Biotechnology (IPMB), University of Heidelberg, Im Neuenheimer Feld 364, D-69120 Heidelberg (Germany); Department of Physics, University of Mainz (JGU), Staudingerweg 7, 55128 Mainz (Germany)

    2016-05-01

    Higher order chromatin structure is not only required to compact and spatially arrange long chromatids within a nucleus, but have also important functional roles, including control of gene expression and DNA processing. However, studies of chromatin nanostructures cannot be performed using conventional widefield and confocal microscopy because of the limited optical resolution. Various methods of superresolution microscopy have been described to overcome this difficulty, like structured illumination and single molecule localization microscopy. We report here that the standard DNA dye Vybrant{sup ®} DyeCycle™ Violet can be used to provide single molecule localization microscopy (SMLM) images of DNA in nuclei of fixed mammalian cells. This SMLM method enabled optical isolation and localization of large numbers of DNA-bound molecules, usually in excess of 10{sup 6} signals in one cell nucleus. The technique yielded high-quality images of nuclear DNA density, revealing subdiffraction chromatin structures of the size in the order of 100 nm; the interchromatin compartment was visualized at unprecedented optical resolution. The approach offers several advantages over previously described high resolution DNA imaging methods, including high specificity, an ability to record images using a single wavelength excitation, and a higher density of single molecule signals than reported in previous SMLM studies. The method is compatible with DNA/multicolor SMLM imaging which employs simple staining methods suited also for conventional optical microscopy. - Highlights: • Super-resolution imaging of nuclear DNA with Vybrant Violet and blue excitation. • 90nm resolution images of DNA structures in optically thick eukaryotic nuclei. • Enhanced resolution confirms the existence of DNA-free regions inside the nucleus. • Optimized imaging conditions enable multicolor super-resolution imaging.

  11. Introducing bioinformatics, the biosciences' genomic revolution

    CERN Document Server

    Zanella, Paolo

    1999-01-01

    The general audience for these lectures is mainly physicists, computer scientists, engineers or the general public wanting to know more about what’s going on in the biosciences. What’s bioinformatics and why is all this fuss being made about it ? What’s this revolution triggered by the human genome project ? Are there any results yet ? What are the problems ? What new avenues of research have been opened up ? What about the technology ? These new developments will be compared with what happened at CERN earlier in its evolution, and it is hoped that the similiraties and contrasts will stimulate new curiosity and provoke new thoughts.

  12. Magnetic Resonance Force Microscopy System

    Data.gov (United States)

    Federal Laboratory Consortium — The Magnetic Resonance Force Microscopy (MRFM) system, developed by ARL, is the world's most sensitive nuclear magnetic resonance (NMR) spectroscopic analysis tool,...

  13. In situ titanium dioxide nanoparticles quantitative microscopy in cells and in C. elegans using nuclear microprobe analysis

    Energy Technology Data Exchange (ETDEWEB)

    Le Trequesser, Quentin [Université de Bordeaux, CENBG, Chemin du solarium, 33175 Gradignan (France); CNRS, UMR 5797, CENBG, Chemin du solarium, 33175 Gradignan (France); CNRS, Université de Bordeaux, ICMCB, 87 avenue du Dr. A. Schweitzer, Pessac F-33608 (France); Saez, Gladys; Devès, Guillaume; Michelet, Claire; Barberet, Philippe [Université de Bordeaux, CENBG, Chemin du solarium, 33175 Gradignan (France); CNRS, UMR 5797, CENBG, Chemin du solarium, 33175 Gradignan (France); Delville, Marie-Hélène [CNRS, Université de Bordeaux, ICMCB, 87 avenue du Dr. A. Schweitzer, Pessac F-33608 (France); Seznec, Hervé, E-mail: herve.seznec@cenbg.in2p3.fr [Université de Bordeaux, CENBG, Chemin du solarium, 33175 Gradignan (France); CNRS, UMR 5797, CENBG, Chemin du solarium, 33175 Gradignan (France)

    2014-12-15

    Detecting and tracking nanomaterials in biological systems is challenging and essential to understand the possible interactions with the living. In this context, in situ analyses were conducted on human skin cells and a multicellular organism (Caenorhabditiselegans) exposed to titanium dioxide nanoparticles (TiO{sub 2} NPs) using nuclear microprobe. Coupled to conventional methods, nuclear microprobe was found to be suitable for accurate description of chemical structure of biological systems and also for detection of native TiO{sub 2} NPs. The method presented herein opens the field to NPs exposure effects analyses and more generally to toxicological analyses assisted by nuclear microprobe. This method will show applications in key research areas where in situ imaging of chemical elements is essential.

  14. High-resolution nuclear track mapping in detailed cellular histology using CR-39 with the contact microscopy technique

    International Nuclear Information System (INIS)

    Amemiya, K.; Takahashi, H.; Kajimoto, Y.; Nakazawa, M.; Yanagie, H.; Hisa, T.; Eriguchi, M.; Nakagawa, Y.; Majima, T.; Kageji, T.; Sakurai, Y.; Kobayashi, T.; Konishi, T.; Hieda, K.; Yasuda, N.; Ogura, K.

    2005-01-01

    In radiation cancer therapies using energetic charged particles such as proton/heavy-ion therapy and boron neutron capture therapy (BNCT), studies on radiation-induced biological response at cellular level are important because the radiation damage from energetic charged particles is highly localized along their paths and the radiation sensitivity is quite different in each cellular organelle. In such studies the information on the position of charged particle impact in biological cells is necessary. A novel method for high-resolution nuclear track mapping in detailed cellular histology has been developed. In this technique, biological specimens mounted on CR-39 plates are exposed to energetic charged particles. The irradiated samples are exposed to UV, and then etched for a short time. Both etch pits of nuclear tracks and relief for transmission UV image of the specimen can be observed on the CR-39 surface with an atomic force microscope (AFM) at about 100 nm resolution

  15. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Early localization of NPA58, a rat nuclear pore-associated protein, to the reforming nuclear envelope during mitosis · Radhika Ganeshan Nandini Rangaraj Veena K Parnaik · More Details Abstract Fulltext PDF. We have studied the mitotic reassembly of the nuclear envelope, using antibodies to nuclear marker proteins and ...

  16. New applications of orientation imaging microscopy (OIM) for characterizing nuclear component failure modes, reliability assessment, and fitness-for-service

    Energy Technology Data Exchange (ETDEWEB)

    Lehockey, E.M.; Brennenstuhl, A.M.; Pagan, S. [Ontario Power Generation, Pickering, Ontario (Canada); Clark, M.A.; Perovic, V. [Kinectrics Inc., Toronto, Ontario (Canada)

    2007-07-01

    Orientation Imaging Microscopy (OIM) has proved a valuable asset for evaluating material performance as far as establishing the root cause and mechanism(s) of in-service degradation, and the likelihood of the onset of future degradation. Strains from deformation/cold work are imaged based on the spatial density of sub-structure distributed globally or surrounding defects/irregularities, which concentrate stresses responsible for driving degradation. This is complimented with measurements of material properties including texture, Taylor Factor, grain boundary structure, and grain size that contribute to resisting propagation of pre-existing defects and/or nucleating future attack. From evaluating the factors driving degradation within the context of microstructure properties that govern material susceptibility come estimates for the likelihood of attack as a necessary element of establishing fitness for service. By way of numerous examples the merits and limitations of OIM are summarized and compared with other characterization techniques. (author)

  17. The potential of 3D-FISH and super-resolution structured illumination microscopy for studies of 3D nuclear architecture: 3D structured illumination microscopy of defined chromosomal structures visualized by 3D (immuno)-FISH opens new perspectives for studies of nuclear architecture.

    Science.gov (United States)

    Markaki, Yolanda; Smeets, Daniel; Fiedler, Susanne; Schmid, Volker J; Schermelleh, Lothar; Cremer, Thomas; Cremer, Marion

    2012-05-01

    Three-dimensional structured illumination microscopy (3D-SIM) has opened up new possibilities to study nuclear architecture at the ultrastructural level down to the ~100 nm range. We present first results and assess the potential using 3D-SIM in combination with 3D fluorescence in situ hybridization (3D-FISH) for the topographical analysis of defined nuclear targets. Our study also deals with the concern that artifacts produced by FISH may counteract the gain in resolution. We address the topography of DAPI-stained DNA in nuclei before and after 3D-FISH, nuclear pores and the lamina, chromosome territories, chromatin domains, and individual gene loci. We also look at the replication patterns of chromocenters and the topographical relationship of Xist-RNA within the inactive X-territory. These examples demonstrate that an appropriately adapted 3D-FISH/3D-SIM approach preserves key characteristics of the nuclear ultrastructure and that the gain in information obtained by 3D-SIM yields new insights into the functional nuclear organization. Copyright © 2012 WILEY Periodicals, Inc.

  18. Taking Nanomedicine Teaching into Practice with Atomic Force Microscopy and Force Spectroscopy

    Science.gov (United States)

    Carvalho, Filomena A.; Freitas, Teresa; Santos, Nuno C.

    2015-01-01

    Atomic force microscopy (AFM) is a useful and powerful tool to study molecular interactions applied to nanomedicine. The aim of the present study was to implement a hands-on atomic AFM course for graduated biosciences and medical students. The course comprises two distinct practical sessions, where students get in touch with the use of an atomic…

  19. Environmental Biosciences Program Report for Year 2

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2005-10-15

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  20. Environmental Biosciences Quarterly Report, September - December, 2005

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2006-01-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.