WorldWideScience

Sample records for bioscience literature search

  1. Full text and figure display improves bioscience literature search.

    Science.gov (United States)

    Divoli, Anna; Wooldridge, Michael A; Hearst, Marti A

    2010-04-14

    When reading bioscience journal articles, many researchers focus attention on the figures and their captions. This observation led to the development of the BioText literature search engine, a freely available Web-based application that allows biologists to search over the contents of Open Access Journals, and see figures from the articles displayed directly in the search results. This article presents a qualitative assessment of this system in the form of a usability study with 20 biologist participants using and commenting on the system. 19 out of 20 participants expressed a desire to use a bioscience literature search engine that displays articles' figures alongside the full text search results. 15 out of 20 participants said they would use a caption search and figure display interface either frequently or sometimes, while 4 said rarely and 1 said undecided. 10 out of 20 participants said they would use a tool for searching the text of tables and their captions either frequently or sometimes, while 7 said they would use it rarely if at all, 2 said they would never use it, and 1 was undecided. This study found evidence, supporting results of an earlier study, that bioscience literature search systems such as PubMed should show figures from articles alongside search results. It also found evidence that full text and captions should be searched along with the article title, metadata, and abstract. Finally, for a subset of users and information needs, allowing for explicit search within captions for figures and tables is a useful function, but it is not entirely clear how to cleanly integrate this within a more general literature search interface. Such a facility supports Open Access publishing efforts, as it requires access to full text of documents and the lifting of restrictions in order to show figures in the search interface.

  2. Full text and figure display improves bioscience literature search.

    Directory of Open Access Journals (Sweden)

    Anna Divoli

    Full Text Available When reading bioscience journal articles, many researchers focus attention on the figures and their captions. This observation led to the development of the BioText literature search engine, a freely available Web-based application that allows biologists to search over the contents of Open Access Journals, and see figures from the articles displayed directly in the search results. This article presents a qualitative assessment of this system in the form of a usability study with 20 biologist participants using and commenting on the system. 19 out of 20 participants expressed a desire to use a bioscience literature search engine that displays articles' figures alongside the full text search results. 15 out of 20 participants said they would use a caption search and figure display interface either frequently or sometimes, while 4 said rarely and 1 said undecided. 10 out of 20 participants said they would use a tool for searching the text of tables and their captions either frequently or sometimes, while 7 said they would use it rarely if at all, 2 said they would never use it, and 1 was undecided. This study found evidence, supporting results of an earlier study, that bioscience literature search systems such as PubMed should show figures from articles alongside search results. It also found evidence that full text and captions should be searched along with the article title, metadata, and abstract. Finally, for a subset of users and information needs, allowing for explicit search within captions for figures and tables is a useful function, but it is not entirely clear how to cleanly integrate this within a more general literature search interface. Such a facility supports Open Access publishing efforts, as it requires access to full text of documents and the lifting of restrictions in order to show figures in the search interface.

  3. The challenge of the Biosciences in Nurse Education: A literature review.

    Science.gov (United States)

    Jensen, Kari Toverud; Knutstad, Unni; Fawcett, Tonks N

    2018-03-25

    To review relevant literature that address the challenges of the biosciences in nurse education. More precisely the review aims to explore the literature, concerning students' learning, learning contexts and methodological issues and identify any significant gaps. Knowledge of anatomy, physiology and biochemistry are essential for the understanding of human beings and for full appreciation of the concepts of illness and disease. The current status would seem to be that the required competencies within bioscience subjects are difficult to acquire and students have high rates of failure. Integrative review. The research were performed on Cinahl, ERIC, Medline and British Nursing Index databases in a period from 2013 until 2017. Descriptive analytical methods were used for the initial research trawl. The search strategy resulted in 23 papers. The results of this review shed light on certain deficiencies in the research field looking at the biosciences in nurse education. There is a distinct lack of intervention studies, and thereby knowledge of how best to support students' learning in effective ways. Of note is that there are no field study approaches identified in the review sample. Many of the papers are single studies and course evaluations which may be seen as too narrow and inadequate a perspective. Students appear satisfied with the courses in the biosciences but there seems to be no correlation between satisfaction and achievement. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  4. Journal of Applied Biosciences: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  5. Can active learning principles be applied to the bioscience assessments of nursing students? A review of the literature.

    Science.gov (United States)

    Bakon, Shannon; Craft, Judy; Christensen, Martin; Wirihana, Lisa

    2016-02-01

    To explore if active learning principles be applied to nursing bioscience assessments and will this influence student perception of confidence in applying theory to practice? A review of the literature utilising searches of various databases including CINAHL, PUBMED, Google Scholar and Mosby's Journal Index. The literature search identified research from twenty-six original articles, two electronic books, one published book and one conference proceedings paper. Bioscience has been identified as an area that nurses struggle to learn in tertiary institutions and then apply to clinical practice. A number of problems have been identified and explored that may contribute to this poor understanding and retention. University academics need to be knowledgeable of innovative teaching and assessing modalities that focus on enhancing student learning and address the integration issues associated with the theory practice gap. Increased bioscience education is associated with improved patient outcomes therefore by addressing this "bioscience problem" and improving the integration of bioscience in clinical practice there will subsequently be an improvement in health care outcomes. From the literature several themes were identified. First there are many problems with teaching nursing students bioscience education. These include class sizes, motivation, concentration, delivery mode, lecturer perspectives, student's previous knowledge, anxiety, and a lack of confidence. Among these influences the type of assessment employed by the educator has not been explored or identified as a contributor to student learning specifically in nursing bioscience instruction. Second that educating could be achieved more effectively if active learning principles were applied and the needs and expectations of the student were met. Lastly, assessment influences student retention and the student experience and as such assessment should be congruent with the subject content, align with the learning

  6. Automatic categorization of diverse experimental information in the bioscience literature

    Science.gov (United States)

    2012-01-01

    Background Curation of information from bioscience literature into biological knowledge databases is a crucial way of capturing experimental information in a computable form. During the biocuration process, a critical first step is to identify from all published literature the papers that contain results for a specific data type the curator is interested in annotating. This step normally requires curators to manually examine many papers to ascertain which few contain information of interest and thus, is usually time consuming. We developed an automatic method for identifying papers containing these curation data types among a large pool of published scientific papers based on the machine learning method Support Vector Machine (SVM). This classification system is completely automatic and can be readily applied to diverse experimental data types. It has been in use in production for automatic categorization of 10 different experimental datatypes in the biocuration process at WormBase for the past two years and it is in the process of being adopted in the biocuration process at FlyBase and the Saccharomyces Genome Database (SGD). We anticipate that this method can be readily adopted by various databases in the biocuration community and thereby greatly reducing time spent on an otherwise laborious and demanding task. We also developed a simple, readily automated procedure to utilize training papers of similar data types from different bodies of literature such as C. elegans and D. melanogaster to identify papers with any of these data types for a single database. This approach has great significance because for some data types, especially those of low occurrence, a single corpus often does not have enough training papers to achieve satisfactory performance. Results We successfully tested the method on ten data types from WormBase, fifteen data types from FlyBase and three data types from Mouse Genomics Informatics (MGI). It is being used in the curation work flow at

  7. Automatic categorization of diverse experimental information in the bioscience literature

    Directory of Open Access Journals (Sweden)

    Fang Ruihua

    2012-01-01

    Full Text Available Abstract Background Curation of information from bioscience literature into biological knowledge databases is a crucial way of capturing experimental information in a computable form. During the biocuration process, a critical first step is to identify from all published literature the papers that contain results for a specific data type the curator is interested in annotating. This step normally requires curators to manually examine many papers to ascertain which few contain information of interest and thus, is usually time consuming. We developed an automatic method for identifying papers containing these curation data types among a large pool of published scientific papers based on the machine learning method Support Vector Machine (SVM. This classification system is completely automatic and can be readily applied to diverse experimental data types. It has been in use in production for automatic categorization of 10 different experimental datatypes in the biocuration process at WormBase for the past two years and it is in the process of being adopted in the biocuration process at FlyBase and the Saccharomyces Genome Database (SGD. We anticipate that this method can be readily adopted by various databases in the biocuration community and thereby greatly reducing time spent on an otherwise laborious and demanding task. We also developed a simple, readily automated procedure to utilize training papers of similar data types from different bodies of literature such as C. elegans and D. melanogaster to identify papers with any of these data types for a single database. This approach has great significance because for some data types, especially those of low occurrence, a single corpus often does not have enough training papers to achieve satisfactory performance. Results We successfully tested the method on ten data types from WormBase, fifteen data types from FlyBase and three data types from Mouse Genomics Informatics (MGI. It is being used in

  8. Automatic categorization of diverse experimental information in the bioscience literature.

    Science.gov (United States)

    Fang, Ruihua; Schindelman, Gary; Van Auken, Kimberly; Fernandes, Jolene; Chen, Wen; Wang, Xiaodong; Davis, Paul; Tuli, Mary Ann; Marygold, Steven J; Millburn, Gillian; Matthews, Beverley; Zhang, Haiyan; Brown, Nick; Gelbart, William M; Sternberg, Paul W

    2012-01-26

    Curation of information from bioscience literature into biological knowledge databases is a crucial way of capturing experimental information in a computable form. During the biocuration process, a critical first step is to identify from all published literature the papers that contain results for a specific data type the curator is interested in annotating. This step normally requires curators to manually examine many papers to ascertain which few contain information of interest and thus, is usually time consuming. We developed an automatic method for identifying papers containing these curation data types among a large pool of published scientific papers based on the machine learning method Support Vector Machine (SVM). This classification system is completely automatic and can be readily applied to diverse experimental data types. It has been in use in production for automatic categorization of 10 different experimental datatypes in the biocuration process at WormBase for the past two years and it is in the process of being adopted in the biocuration process at FlyBase and the Saccharomyces Genome Database (SGD). We anticipate that this method can be readily adopted by various databases in the biocuration community and thereby greatly reducing time spent on an otherwise laborious and demanding task. We also developed a simple, readily automated procedure to utilize training papers of similar data types from different bodies of literature such as C. elegans and D. melanogaster to identify papers with any of these data types for a single database. This approach has great significance because for some data types, especially those of low occurrence, a single corpus often does not have enough training papers to achieve satisfactory performance. We successfully tested the method on ten data types from WormBase, fifteen data types from FlyBase and three data types from Mouse Genomics Informatics (MGI). It is being used in the curation work flow at WormBase for

  9. Beyond MEDLINE for literature searches.

    Science.gov (United States)

    Conn, Vicki S; Isaramalai, Sang-arun; Rath, Sabyasachi; Jantarakupt, Peeranuch; Wadhawan, Rohini; Dash, Yashodhara

    2003-01-01

    To describe strategies for a comprehensive literature search. MEDLINE searches result in limited numbers of studies that are often biased toward statistically significant findings. Diversified search strategies are needed. Empirical evidence about the recall and precision of diverse search strategies is presented. Challenges and strengths of each search strategy are identified. Search strategies vary in recall and precision. Often sensitivity and specificity are inversely related. Valuable search strategies include examination of multiple diverse computerized databases, ancestry searches, citation index searches, examination of research registries, journal hand searching, contact with the "invisible college," examination of abstracts, Internet searches, and contact with sources of synthesized information. Extending searches beyond MEDLINE enables researchers to conduct more systematic comprehensive searches.

  10. Electronic biomedical literature search for budding researcher.

    Science.gov (United States)

    Thakre, Subhash B; Thakre S, Sushama S; Thakre, Amol D

    2013-09-01

    Search for specific and well defined literature related to subject of interest is the foremost step in research. When we are familiar with topic or subject then we can frame appropriate research question. Appropriate research question is the basis for study objectives and hypothesis. The Internet provides a quick access to an overabundance of the medical literature, in the form of primary, secondary and tertiary literature. It is accessible through journals, databases, dictionaries, textbooks, indexes, and e-journals, thereby allowing access to more varied, individualised, and systematic educational opportunities. Web search engine is a tool designed to search for information on the World Wide Web, which may be in the form of web pages, images, information, and other types of files. Search engines for internet-based search of medical literature include Google, Google scholar, Scirus, Yahoo search engine, etc., and databases include MEDLINE, PubMed, MEDLARS, etc. Several web-libraries (National library Medicine, Cochrane, Web of Science, Medical matrix, Emory libraries) have been developed as meta-sites, providing useful links to health resources globally. A researcher must keep in mind the strengths and limitations of a particular search engine/database while searching for a particular type of data. Knowledge about types of literature, levels of evidence, and detail about features of search engine as available, user interface, ease of access, reputable content, and period of time covered allow their optimal use and maximal utility in the field of medicine. Literature search is a dynamic and interactive process; there is no one way to conduct a search and there are many variables involved. It is suggested that a systematic search of literature that uses available electronic resource effectively, is more likely to produce quality research.

  11. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Cover page gallery. Cover page gallery. Journal of Biosciences. Cover page. Journal of Biosciences. Current Issue : Vol. 43, Issue 1. Current Issue Volume 43 | Issue 1. March 2018. Home · Volumes & Issues · Special Issues · Forthcoming Articles · Gallery of Cover Art · Search ...

  12. Optimizing literature search in systematic reviews

    DEFF Research Database (Denmark)

    Aagaard, Thomas; Lund, Hans; Juhl, Carsten Bogh

    2016-01-01

    BACKGROUND: When conducting systematic reviews, it is essential to perform a comprehensive literature search to identify all published studies relevant to the specific research question. The Cochrane Collaborations Methodological Expectations of Cochrane Intervention Reviews (MECIR) guidelines...... of musculoskeletal disorders. METHODS: Data sources were systematic reviews published by the Cochrane Musculoskeletal Review Group, including at least five RCTs, reporting a search history, searching MEDLINE, EMBASE, CENTRAL, and adding reference- and hand-searching. Additional databases were deemed eligible...... if they indexed RCTs, were in English and used in more than three of the systematic reviews. Relative recall was calculated as the number of studies identified by the literature search divided by the number of eligible studies i.e. included studies in the individual systematic reviews. Finally, cumulative median...

  13. Literature searches on Ayurveda: An update.

    Science.gov (United States)

    Aggithaya, Madhur G; Narahari, Saravu R

    2015-01-01

    The journals that publish on Ayurveda are increasingly indexed by popular medical databases in recent years. However, many Eastern journals are not indexed biomedical journal databases such as PubMed. Literature searches for Ayurveda continue to be challenging due to the nonavailability of active, unbiased dedicated databases for Ayurvedic literature. In 2010, authors identified 46 databases that can be used for systematic search of Ayurvedic papers and theses. This update reviewed our previous recommendation and identified current and relevant databases. To update on Ayurveda literature search and strategy to retrieve maximum publications. Author used psoriasis as an example to search previously listed databases and identify new. The population, intervention, control, and outcome table included keywords related to psoriasis and Ayurvedic terminologies for skin diseases. Current citation update status, search results, and search options of previous databases were assessed. Eight search strategies were developed. Hundred and five journals, both biomedical and Ayurveda, which publish on Ayurveda, were identified. Variability in databases was explored to identify bias in journal citation. Five among 46 databases are now relevant - AYUSH research portal, Annotated Bibliography of Indian Medicine, Digital Helpline for Ayurveda Research Articles (DHARA), PubMed, and Directory of Open Access Journals. Search options in these databases are not uniform, and only PubMed allows complex search strategy. "The Researches in Ayurveda" and "Ayurvedic Research Database" (ARD) are important grey resources for hand searching. About 44/105 (41.5%) journals publishing Ayurvedic studies are not indexed in any database. Only 11/105 (10.4%) exclusive Ayurveda journals are indexed in PubMed. AYUSH research portal and DHARA are two major portals after 2010. It is mandatory to search PubMed and four other databases because all five carry citations from different groups of journals. The hand

  14. The Imperative Of Literature Search For Research In Nigeria | Madu ...

    African Journals Online (AJOL)

    The paper while advancing reasons for literature search described how the library can assist in literature search. It finally discussed the various approaches and levels of search especially on the web and the problems researchers are most likely to encounter. Keywords: Research, Literature Search, Nigeria. The Information ...

  15. A beginner's guide to the literature search in medical education.

    Science.gov (United States)

    Martin, S; Hussain, Z; Boyle, J G

    2017-05-01

    Conducting a literature search can be a daunting prospect if you have not done it before. This article aims to provide a beginner's guide to searching the medical education literature, by describing how to construct an effective search strategy, the resources that are available and the basics of how searching works.

  16. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Journal of Biosciences. Current Issue : Vol. 43, Issue 1 · Current Issue Volume 43 | Issue 1. March 2018. Home · Volumes & Issues · Special Issues · Forthcoming Articles · Gallery of Cover Art · Search · Online submission at eBiosciences · Editorial Board · Information for Authors · Subscription ...

  17. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Journal of Biosciences. Current Issue : Vol. 43, Issue 1. Current Issue Volume 43 | Issue 1. March 2018. Home · Volumes & Issues · Special Issues · Forthcoming Articles · Gallery of Cover Art · Search · Online submission at eBiosciences · Editorial Board · Information for Authors · Subscription ...

  18. Analysis of a librarian-mediated literature search service.

    Science.gov (United States)

    Friesen, Carol; Lê, Mê-Linh; Cooke, Carol; Raynard, Melissa

    2015-01-01

    Librarian-mediated literature searching is a key service provided at medical libraries. This analysis outlines ten years of data on 19,248 literature searches and describes information on the volume and frequency of search requests, time spent per search, databases used, and professional designations of the patron requestors. Combined with information on best practices for expert searching and evaluations of similar services, these findings were used to form recommendations on the improvement and standardization of a literature search service at a large health library system.

  19. Searching for Grey Literature for Systematic Reviews: Challenges and Benefits

    Science.gov (United States)

    Mahood, Quenby; Van Eerd, Dwayne; Irvin, Emma

    2014-01-01

    There is ongoing interest in including grey literature in systematic reviews. Including grey literature can broaden the scope to more relevant studies, thereby providing a more complete view of available evidence. Searching for grey literature can be challenging despite greater access through the Internet, search engines and online bibliographic…

  20. [The smile line, a literature search].

    Science.gov (United States)

    van der Geld, P A; van Waas, M A

    2003-09-01

    Beautiful teeth, visible when smiling, are in line with the present ideal of beauty. The display of teeth when smiling is determined by the smile line: the projection of the lower border of the upper lip on the maxillary teeth when smiling. On the basis of a literature search the determining methods of the smile line are discussed, demographic data of the position of the smile line are given, and factors of influence are examined. There is no unequivocal method for determining the position of the smile line. A rough distinction can be made between qualitative and (semi)-quantitative methods. The (semi)-quantitative methods have clear advantages for research purposes, but their reliability is unknown. It was demonstrated that among minimally 40% of subjects the maxillary gingiva was not visible when smiling. The mandibular gingiva was not visible when smiling among more than 90% of subjects. Furthermore, it appeared that among women the smile line was on average higher situated than among men and that it has not yet been proven that the smile line will be situated lower when growing older.

  1. Social Work Literature Searching: Current Issues with Databases and Online Search Engines

    Science.gov (United States)

    McGinn, Tony; Taylor, Brian; McColgan, Mary; McQuilkan, Janice

    2016-01-01

    Objectives: To compare the performance of a range of search facilities; and to illustrate the execution of a comprehensive literature search for qualitative evidence in social work. Context: Developments in literature search methods and comparisons of search facilities help facilitate access to the best available evidence for social workers.…

  2. Computer-based literature search in medical institutions in India

    Directory of Open Access Journals (Sweden)

    Kalita Jayantee

    2007-01-01

    Full Text Available Aim: To study the use of computer-based literature search and its application in clinical training and patient care as a surrogate marker of evidence-based medicine. Materials and Methods: A questionnaire comprising of questions on purpose (presentation, patient management, research, realm (site accessed, nature and frequency of search, effect, infrastructure, formal training in computer based literature search and suggestions for further improvement were sent to residents and faculty of a Postgraduate Medical Institute (PGI and a Medical College. The responses were compared amongst different subgroups of respondents. Results: Out of 300 subjects approached 194 responded; of whom 103 were from PGI and 91 from Medical College. There were 97 specialty residents, 58 super-specialty residents and 39 faculty members. Computer-based literature search was done at least once a month by 89% though there was marked variability in frequency and extent. The motivation for computer-based literature search was for presentation in 90%, research in 65% and patient management in 60.3%. The benefit of search was acknowledged in learning and teaching by 80%, research by 65% and patient care by 64.4% of respondents. Formal training in computer based literature search was received by 41% of whom 80% were residents. Residents from PGI did more frequent and more extensive computer-based literature search, which was attributed to better infrastructure and training. Conclusion: Training and infrastructure both are crucial for computer-based literature search, which may translate into evidence based medicine.

  3. Comparison of PubMed and Google Scholar literature searches.

    Science.gov (United States)

    Anders, Michael E; Evans, Dennis P

    2010-05-01

    Literature searches are essential to evidence-based respiratory care. To conduct literature searches, respiratory therapists rely on search engines to retrieve information, but there is a dearth of literature on the comparative efficiencies of search engines for researching clinical questions in respiratory care. To compare PubMed and Google Scholar search results for clinical topics in respiratory care to that of a benchmark. We performed literature searches with PubMed and Google Scholar, on 3 clinical topics. In PubMed we used the Clinical Queries search filter. In Google Scholar we used the search filters in the Advanced Scholar Search option. We used the reference list of a related Cochrane Collaboration evidence-based systematic review as the benchmark for each of the search results. We calculated recall (sensitivity) and precision (positive predictive value) with 2 x 2 contingency tables. We compared the results with the chi-square test of independence and Fisher's exact test. PubMed and Google Scholar had similar recall for both overall search results (71% vs 69%) and full-text results (43% vs 51%). PubMed had better precision than Google Scholar for both overall search results (13% vs 0.07%, P PubMed searches with the Clinical Queries filter are more precise than with the Advanced Scholar Search in Google Scholar for respiratory care topics. PubMed appears to be more practical to conduct efficient, valid searches for informing evidence-based patient-care protocols, for guiding the care of individual patients, and for educational purposes.

  4. A student's guide to searching the literature using online databases

    Science.gov (United States)

    Miller, Casey W.; Belyea, Dustin; Chabot, Michelle; Messina, Troy

    2012-02-01

    A method is described to empower students to efficiently perform general and specific literature searches using online resources [Miller et al., Am. J. Phys. 77, 1112 (2009)]. The method was tested on multiple groups, including undergraduate and graduate students with varying backgrounds in scientific literature searches. Students involved in this study showed marked improvement in their awareness of how and where to find scientific information. Repeated exposure to literature searching methods appears worthwhile, starting early in the undergraduate career, and even in graduate school orientation.

  5. [Systematic literature search in PubMed : A short introduction].

    Science.gov (United States)

    Blümle, A; Lagrèze, W A; Motschall, E

    2018-03-01

    In order to identify current (and relevant) evidence for a specific clinical question within the unmanageable amount of information available, solid skills in performing a systematic literature search are essential. An efficient approach is to search a biomedical database containing relevant literature citations of study reports. The best known database is MEDLINE, which is searchable for free via the PubMed interface. In this article, we explain step by step how to perform a systematic literature search via PubMed by means of an example research question in the field of ophthalmology. First, we demonstrate how to translate the clinical problem into a well-framed and searchable research question, how to identify relevant search terms and how to conduct a text word search and a search with keywords in medical subject headings (MeSH) terms. We then show how to limit the number of search results if the search yields too many irrelevant hits and how to increase the number in the case of too few citations. Finally, we summarize all essential principles that guide a literature search via PubMed.

  6. Search of medical literature for indoor carbon monoxide exposure

    Energy Technology Data Exchange (ETDEWEB)

    Brennan, T.; Ivanovich, M.

    1995-12-01

    This report documents a literature search on carbon monoxide. The search was limited to the medical and toxicological databases at the National Library of Medicine (MEDLARS). The databases searched were Medline, Toxline and TOXNET. Searches were performed using a variety of strategies. Combinations of the following keywords were used: carbon, monoxide, accidental, residential, occult, diagnosis, misdiagnosis, heating, furnace, and indoor. The literature was searched from 1966 to the present. Over 1000 references were identified and summarized using the following abbreviations: The major findings of the search are: (1) Acute and subacute carbon monoxide exposures result in a large number of symptoms affecting the brain, kidneys, respiratory system, retina, and motor functions. (2) Acute and subacute carbon monoxide (CO) poisonings have been misdiagnosed on many occasions. (3) Very few systematic investigations have been made into the frequency and consequences of carbon monoxide poisonings.

  7. Searching the scientific literature: implications for quantitative and qualitative reviews.

    Science.gov (United States)

    Wu, Yelena P; Aylward, Brandon S; Roberts, Michael C; Evans, Spencer C

    2012-08-01

    Literature reviews are an essential step in the research process and are included in all empirical and review articles. Electronic databases are commonly used to gather this literature. However, several factors can affect the extent to which relevant articles are retrieved, influencing future research and conclusions drawn. The current project examined articles obtained by comparable search strategies in two electronic archives using an exemplar search to illustrate factors that authors should consider when designing their own search strategies. Specifically, literature searches were conducted in PsycINFO and PubMed targeting review articles on two exemplar disorders (bipolar disorder and attention deficit/hyperactivity disorder) and issues of classification and/or differential diagnosis. Articles were coded for relevance and characteristics of article content. The two search engines yielded significantly different proportions of relevant articles overall and by disorder. Keywords differed across search engines for the relevant articles identified. Based on these results, it is recommended that when gathering literature for review papers, multiple search engines should be used, and search syntax and strategies be tailored to the unique capabilities of particular engines. For meta-analyses and systematic reviews, authors may consider reporting the extent to which different archives or sources yielded relevant articles for their particular review. Copyright © 2012 Elsevier Ltd. All rights reserved.

  8. Evidence-based medicine - searching the medical literature. Part 1.

    African Journals Online (AJOL)

    Ann Burgess

    password for access via HINARIa2 use that to log in. Then you can retrieve articles from the 6000 journals that will be available to you. You cannot retrieve the full text from journals that do not allow free access or HINARI access. How to search the literature on the internet. Before you start your search take a moment to think ...

  9. Searching the online biomedical literature from developing countries

    African Journals Online (AJOL)

    Administrator

    This commentary highlights popular research literature databases and the use of the internet to obtain valuable research information. These literature retrieval methods include the use of the popular. PubMed as well as internet search engines. Specific websites catering to developing countries' information and journals' ...

  10. Searching the online biomedical literature from developing countries ...

    African Journals Online (AJOL)

    This commentary highlights popular research literature databases and the use of the internet to obtain valuable research information. These literature retrieval methods include the use of the popular PubMed as well as internet search engines. Specific websites catering to developing countries' information and journals' ...

  11. Thick-film analysis: literature search and bibliography

    International Nuclear Information System (INIS)

    Gehman, R.W.

    1981-09-01

    A literature search was conducted to support development of in-house diagnostic testing of thick film materials for hybrid microcircuits. A background literature review covered thick film formulation, processing, structure, and performance. Important material properties and tests were identified and several test procedures were obtained. Several tests were selected for thick film diagnosis at Bendix Kansas City. 126 references

  12. 75 FR 25239 - Integrated Risk Information System (IRIS); Announcement of Availability of Literature Searches...

    Science.gov (United States)

    2010-05-07

    ... Information System (IRIS); Announcement of Availability of Literature Searches for IRIS Assessments AGENCY: Environmental Protection Agency. ACTION: Notice; Announcement of availability of literature searches for IRIS... the availability of literature searches for four IRIS assessments and requesting scientific...

  13. The impact of PICO as a search strategy tool on literature search quality

    DEFF Research Database (Denmark)

    Eriksen, Mette Brandt; Frandsen, Tove Faber

    2018-01-01

    Objective: This review aimed to determine, if the use of the PICO model (Patient Intervention Comparison Outcome) as a search strategy tool affects the quality of the literature search. Methods: A comprehensive literature search was conducted in: PubMed, Embase, CINAHL, PsycInfo, Cochrane Library...... and three studies were included, data was extracted, risk of bias was assessed and a qualitative analysis was conducted. The included studies compared PICO to PIC or link to related articles in PubMed; PICOS and SPIDER. One study compared PICO to unguided searching. Due to differences in intervention...

  14. Manned-Unmanned Teaming of Aircraft - Literature Search

    Science.gov (United States)

    2013-12-01

    restricted to 2003 2013. Literature searches were conducted in eight databases Aerospace and High Technology, Scopus , NTIS, Inspec, Compendex, DTIC, Jane’si...Buddy Unmanned wingman Manned-Unmanned Teaming Dec 2013 Page 35 of 37 7.1.2 Sources Online databases • Scopus • Aerospace and High Technology

  15. Clinical leadership and nursing explored: A literature search.

    Science.gov (United States)

    Stanley, David; Stanley, Karen

    2017-10-27

    To explore what we know of the concept of clinical leadership and what the term means. Clues to the definition of clinical leadership, the attributes of effective and less effective clinical leaders, models of clinical leadership and the barriers that hinder clinical leadership development were explored. While nursing leadership and healthcare leadership are terms that have been evident in nursing and health industry literature for many decades, clinical leadership is a relatively new term and is may still be misunderstood. A search was undertaken of formal and informal literature using a library database and a range of search engines for the words "clinical leadership" and "clinical leadership in nursing." In each case, the full search parameters were employed with searches between 1974-2016. Full-text articles were requested, and English was the preferred language. In total, 3,259 publications were located through seven database search tools, although these included a large number of duplications. Following further informal searches and removing irrelevant material, 27 research or literature review focused papers were retained that included 17 qualitative studies, one quantitative study, one mixed method study, one Delphi study and two that compared other research studies. As well, five literature reviews were retained in the synthesis. The data synthesis resulted five categories: definitions of clinical leadership, characteristics most likely or least associated with clinical leadership, models applied to clinical leadership and limits to clinical leadership development. Clinical leaders are recognised for having their values and beliefs parallel their actions and interventions. They are found across the spectrum of health organisations, often at the highest level for clinical interaction, but not commonly at the highest management level in a ward or unit team and they are seen in all clinical environments. Clinical Leadership and an understanding on how

  16. The importance of species name synonyms in literature searches

    Science.gov (United States)

    Guala, Gerald

    2016-01-01

    The synonyms of biological species names are shown to be an important component in comprehensive searches of electronic scientific literature databases but they are not well leveraged within the major literature databases examined. For accepted or valid species names in the Integrated Taxonomic Information System (ITIS) which have synonyms in the system, and which are found in citations within PLoS, PMC, PubMed or Scopus, both the percentage of species for which citations will not be found if synonyms are not used, and the percentage increase in number of citations found by including synonyms are very often substantial. However, there is no correlation between the number of synonyms per species and the magnitude of the effect. Further, the number of citations found does not generally increase proportionally to the number of synonyms available. Users looking for literature on specific species across all of the resources investigated here are often missing large numbers of citations if they are not manually augmenting their searches with synonyms. Of course, missing citations can have serious consequences by effectively hiding critical information. Literature searches should include synonym relationships and a new web service in ITIS, with examples of how to apply it to this issue, was developed as a result of this study, and is here announced, to aide in this.

  17. The Importance of Species Name Synonyms in Literature Searches.

    Science.gov (United States)

    Guala, Gerald F

    2016-01-01

    The synonyms of biological species names are shown to be an important component in comprehensive searches of electronic scientific literature databases but they are not well leveraged within the major literature databases examined. For accepted or valid species names in the Integrated Taxonomic Information System (ITIS) which have synonyms in the system, and which are found in citations within PLoS, PMC, PubMed or Scopus, both the percentage of species for which citations will not be found if synonyms are not used, and the percentage increase in number of citations found by including synonyms are very often substantial. However, there is no correlation between the number of synonyms per species and the magnitude of the effect. Further, the number of citations found does not generally increase proportionally to the number of synonyms available. Users looking for literature on specific species across all of the resources investigated here are often missing large numbers of citations if they are not manually augmenting their searches with synonyms. Of course, missing citations can have serious consequences by effectively hiding critical information. Literature searches should include synonym relationships and a new web service in ITIS, with examples of how to apply it to this issue, was developed as a result of this study, and is here announced, to aide in this.

  18. The Importance of Species Name Synonyms in Literature Searches.

    Directory of Open Access Journals (Sweden)

    Gerald F Guala

    Full Text Available The synonyms of biological species names are shown to be an important component in comprehensive searches of electronic scientific literature databases but they are not well leveraged within the major literature databases examined. For accepted or valid species names in the Integrated Taxonomic Information System (ITIS which have synonyms in the system, and which are found in citations within PLoS, PMC, PubMed or Scopus, both the percentage of species for which citations will not be found if synonyms are not used, and the percentage increase in number of citations found by including synonyms are very often substantial. However, there is no correlation between the number of synonyms per species and the magnitude of the effect. Further, the number of citations found does not generally increase proportionally to the number of synonyms available. Users looking for literature on specific species across all of the resources investigated here are often missing large numbers of citations if they are not manually augmenting their searches with synonyms. Of course, missing citations can have serious consequences by effectively hiding critical information. Literature searches should include synonym relationships and a new web service in ITIS, with examples of how to apply it to this issue, was developed as a result of this study, and is here announced, to aide in this.

  19. Connecting Archaeological Data and Grey Literature via Semantic Cross Search

    Directory of Open Access Journals (Sweden)

    Douglas Tudhope

    2011-07-01

    Full Text Available Differing terminology and database structure hinders meaningful cross search of excavation datasets. Matching free text grey literature reports with datasets poses yet more challenges. Conventional search techniques are unable to cross search between archaeological datasets and Web-based grey literature. Results are reported from two AHRC funded research projects that investigated the use of semantic techniques to link digital archive databases, vocabularies and associated grey literature. STAR (Semantic Technologies for Archaeological Resources was a collaboration between the University of Glamorgan, Hypermedia Research Unit and English Heritage (EH. The main outcome is a research Demonstrator (available online, which cross searches over excavation datasets from different database schemas, including Raunds Roman, Raunds Prehistoric, Museum of London, Silchester Roman and Stanwick sampling. The system additionally cross searches over an extract of excavation reports from the OASIS index of grey literature, operated by the Archaeology Data Service (ADS. A conceptual framework provided by the CIDOC Conceptual Reference Model (CRM integrates the different database structures and the metadata automatically generated from the OASIS reports by natural language processing techniques. The methods employed for extracting semantic RDF representations from the datasets and the information extraction from grey literature are described. The STELLAR project provides freely available tools to reduce the costs of mapping and extracting data to semantic search systems such as the Demonstrator and to linked data representation generally. Detailed use scenarios (and a screen capture video provide a basis for a discussion of key issues, including cost-benefits, ontology modelling, mapping, terminology control, semantic implementation and information extraction issues. The scenarios show that semantic interoperability can be achieved by mapping and extracting

  20. Paramedic literature search filters: optimised for clinicians and academics.

    Science.gov (United States)

    Olaussen, Alexander; Semple, William; Oteir, Alaa; Todd, Paula; Williams, Brett

    2017-10-11

    Search filters aid clinicians and academics to accurately locate literature. Despite this, there is no search filter or Medical Subject Headings (MeSH) term pertaining to paramedics. Therefore, the aim of this study was to create two filters to meet to different needs of paramedic clinicians and academics. We created a gold standard from a reference set, which we measured against single terms and search filters. The words and phrases used stemmed from selective exclusion of terms from the previously published Prehospital Search Filter 2.0 as well as a Delphi session with an expert panel of paramedic researchers. Independent authors deemed articles paramedic-relevant or not following an agreed definition. We measured sensitivity, specificity, accuracy and number needed to read (NNR). We located 2102 articles of which 431 (20.5%) related to paramedics. The performance of single terms was on average of high specificity (97.1% (Standard Deviation 7.4%), but of poor sensitivity (12.0%, SD 18.7%). The NNR ranged from 1 to 8.6. The sensitivity-maximising search filter yielded 98.4% sensitivity, with a specificity of 74.3% and a NNR of 2. The specificity-maximising filter achieved 88.3% in specificity, which only lowered the sensitivity to 94.7%, and thus a NNR of 1.48. We have created the first two paramedic specific search filters, one optimised for sensitivity and one optimised for specificity. The sensitivity-maximising search filter yielded 98.4% sensitivity, and a NNR of 2. The specificity-maximising filter achieved 88.3% in specificity, which only lowered the sensitivity to 94.7%, and a NNR of 1.48. A paramedic MeSH term is needed.

  1. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2016-08-26

    Aug 26, 2016 ... Home; Journals; Journal of Biosciences; Search ... part of the email address of all email addresses used by the office of Indian Academy of Sciences, including those of the staff, the journals, various programmes, and Current Science, has changed from 'ias.ernet.in' (or 'academy.ias.ernet.in') to 'ias.ac.in'.

  2. Factors affecting the diffusion of online end user literature searching.

    Science.gov (United States)

    Ash, J S

    1999-01-01

    The aim of this study was to identify factors that affect diffusion of usage of online end user literature searching. Fifteen factors clustered into three attribute sets (innovation attributes, organizational attributes, and marketing attributes) were measured to study their effect on the diffusion of online searching within institutions. A random sample of sixty-seven academic health sciences centers was selected and then 1,335 library and informatics staff members at those institutions were surveyed by mail with electronic mail follow-up. Multiple regression analysis was performed. The survey yielded a 41% response rate with electronic mail follow-up being particularly effective. Two dependent variables, internal diffusion (spread of diffusion) and infusion (depth of diffusion), were measured. There was little correlation between them, indicating they measured different things. Fifteen independent variables clustered into three attribute sets were measured. The innovation attributes set was significant for both internal diffusion and infusion. Significant individual variables were visibility for internal diffusion and image enhancement effects (negative relation) as well as visibility for infusion (depth of diffusion). Organizational attributes were also significant predictors for both dependent variables. No individual variables were significant for internal diffusion. Communication, management support (negative relation), rewards, and existence of champions were significant for infusion. Marketing attributes were not significant predictors. Successful diffusion of online end user literature searching is dependent on the visibility of the systems, communication among, rewards to, and peers of possible users who promote use (champions). Personal image enhancement effects have a negative relation to infusion, possibly because the use of intermediaries is still seen as the more luxurious way to have searches done. Management support also has a negative relation to

  3. PIE the search: searching PubMed literature for protein interaction information.

    Science.gov (United States)

    Kim, Sun; Kwon, Dongseop; Shin, Soo-Yong; Wilbur, W John

    2012-02-15

    Finding protein-protein interaction (PPI) information from literature is challenging but an important issue. However, keyword search in PubMed(®) is often time consuming because it requires a series of actions that refine keywords and browse search results until it reaches a goal. Due to the rapid growth of biomedical literature, it has become more difficult for biologists and curators to locate PPI information quickly. Therefore, a tool for prioritizing PPI informative articles can be a useful assistant for finding this PPI-relevant information. PIE (Protein Interaction information Extraction) the search is a web service implementing a competition-winning approach utilizing word and syntactic analyses by machine learning techniques. For easy user access, PIE the search provides a PubMed-like search environment, but the output is the list of articles prioritized by PPI confidence scores. By obtaining PPI-related articles at high rank, researchers can more easily find the up-to-date PPI information, which cannot be found in manually curated PPI databases. http://www.ncbi.nlm.nih.gov/IRET/PIE/.

  4. 75 FR 76982 - Integrated Risk Information System (IRIS); Announcement of Availability of Literature Searches...

    Science.gov (United States)

    2010-12-10

    ... Information System (IRIS); Announcement of Availability of Literature Searches for IRIS Assessments AGENCY: Environmental Protection Agency. ACTION: Announcement of availability of literature searches for IRIS... the availability of literature searches for four IRIS assessments, acetaldehyde (CAS No. 75-07-0...

  5. 76 FR 13402 - Integrated Risk Information System (IRIS); Announcement of Availability of Literature Searches...

    Science.gov (United States)

    2011-03-11

    ... Information System (IRIS); Announcement of Availability of Literature Searches for IRIS Assessments AGENCY: Environmental Protection Agency. ACTION: Announcement of availability of literature searches for IRIS... the availability of literature searches for cobalt (CASRN 7440-48-4) and inorganic cobalt compounds...

  6. 77 FR 20817 - Integrated Risk Information System (IRIS); Announcement of Availability of Literature Searches...

    Science.gov (United States)

    2012-04-06

    ... System (IRIS); Announcement of Availability of Literature Searches for IRIS Assessments AGENCY: Environmental Protection Agency. ACTION: Announcement of availability of literature searches for IRIS... the availability of literature searches for acetaldehyde (75-07-0) and 1,2,3-trimethlybenzene (526-73...

  7. 77 FR 41784 - Integrated Risk Information System (IRIS); Announcement of Availability of Literature Searches...

    Science.gov (United States)

    2012-07-16

    ... System (IRIS); Announcement of Availability of Literature Searches for IRIS Assessments AGENCY: Environmental Protection Agency. ACTION: Notice of availability of a literature search for benzo(a)pyrene... availability of a literature search for benzo(a)pyrene (CASRN 50- 32-8). EPA is also requesting scientific...

  8. Sandia National Laboratories: Research: Bioscience

    Science.gov (United States)

    biological agents. We integrate our renowned engineering, nanotechnology, and computational capabilities to Foundations Bioscience Computing & Information Science Electromagnetics Engineering Science Geoscience Opportunities Microsensors Bioscience Leadership Computing and Information Science Engineering Science

  9. The Role of Google Scholar in Evidence Reviews and Its Applicability to Grey Literature Searching

    Science.gov (United States)

    Haddaway, Neal Robert; Collins, Alexandra Mary; Coughlin, Deborah; Kirk, Stuart

    2015-01-01

    Google Scholar (GS), a commonly used web-based academic search engine, catalogues between 2 and 100 million records of both academic and grey literature (articles not formally published by commercial academic publishers). Google Scholar collates results from across the internet and is free to use. As a result it has received considerable attention as a method for searching for literature, particularly in searches for grey literature, as required by systematic reviews. The reliance on GS as a standalone resource has been greatly debated, however, and its efficacy in grey literature searching has not yet been investigated. Using systematic review case studies from environmental science, we investigated the utility of GS in systematic reviews and in searches for grey literature. Our findings show that GS results contain moderate amounts of grey literature, with the majority found on average at page 80. We also found that, when searched for specifically, the majority of literature identified using Web of Science was also found using GS. However, our findings showed moderate/poor overlap in results when similar search strings were used in Web of Science and GS (10–67%), and that GS missed some important literature in five of six case studies. Furthermore, a general GS search failed to find any grey literature from a case study that involved manual searching of organisations’ websites. If used in systematic reviews for grey literature, we recommend that searches of article titles focus on the first 200 to 300 results. We conclude that whilst Google Scholar can find much grey literature and specific, known studies, it should not be used alone for systematic review searches. Rather, it forms a powerful addition to other traditional search methods. In addition, we advocate the use of tools to transparently document and catalogue GS search results to maintain high levels of transparency and the ability to be updated, critical to systematic reviews. PMID:26379270

  10. The Role of Google Scholar in Evidence Reviews and Its Applicability to Grey Literature Searching.

    Science.gov (United States)

    Haddaway, Neal Robert; Collins, Alexandra Mary; Coughlin, Deborah; Kirk, Stuart

    2015-01-01

    Google Scholar (GS), a commonly used web-based academic search engine, catalogues between 2 and 100 million records of both academic and grey literature (articles not formally published by commercial academic publishers). Google Scholar collates results from across the internet and is free to use. As a result it has received considerable attention as a method for searching for literature, particularly in searches for grey literature, as required by systematic reviews. The reliance on GS as a standalone resource has been greatly debated, however, and its efficacy in grey literature searching has not yet been investigated. Using systematic review case studies from environmental science, we investigated the utility of GS in systematic reviews and in searches for grey literature. Our findings show that GS results contain moderate amounts of grey literature, with the majority found on average at page 80. We also found that, when searched for specifically, the majority of literature identified using Web of Science was also found using GS. However, our findings showed moderate/poor overlap in results when similar search strings were used in Web of Science and GS (10-67%), and that GS missed some important literature in five of six case studies. Furthermore, a general GS search failed to find any grey literature from a case study that involved manual searching of organisations' websites. If used in systematic reviews for grey literature, we recommend that searches of article titles focus on the first 200 to 300 results. We conclude that whilst Google Scholar can find much grey literature and specific, known studies, it should not be used alone for systematic review searches. Rather, it forms a powerful addition to other traditional search methods. In addition, we advocate the use of tools to transparently document and catalogue GS search results to maintain high levels of transparency and the ability to be updated, critical to systematic reviews.

  11. Journal of Biosciences

    Indian Academy of Sciences (India)

    Madhu

    The Journal of Biosciences welcomes contributions containing the results of original research in any area of biology. Both brief communications (within 4 typed pages or 1500 words of text) and full-length articles are accepted. There are no page charges for printing colour photographs. Fifty reprints will be supplied free of ...

  12. Journal of Applied Biosciences

    African Journals Online (AJOL)

    The Journal of Applied Biosciences provides a forum for scholars and practitioners in all spheres of biological sciences to publish their research findings or theoretical concepts and ideas of a scientific nature. Other websites related to this journal: http://m.elewa.org/Journals/about-jab/ ...

  13. Literature search strategies for conducting knowledge-building and theory-generating qualitative systematic reviews.

    Science.gov (United States)

    Finfgeld-Connett, Deborah; Johnson, E Diane

    2013-01-01

    To report literature search strategies for the purpose of conducting knowledge-building and theory-generating qualitative systematic reviews. Qualitative systematic reviews lie on a continuum from knowledge-building and theory-generating to aggregating and summarizing. Different types of literature searches are needed to optimally support these dissimilar reviews. Articles published between 1989-Autumn 2011. These documents were identified using a hermeneutic approach and multiple literature search strategies. Redundancy is not the sole measure of validity when conducting knowledge-building and theory-generating systematic reviews. When conducting these types of reviews, literature searches should be consistent with the goal of fully explicating concepts and the interrelationships among them. To accomplish this objective, a 'berry picking' approach is recommended along with strategies for overcoming barriers to finding qualitative research reports. To enhance integrity of knowledge-building and theory-generating systematic reviews, reviewers are urged to make literature search processes as transparent as possible, despite their complexity. This includes fully explaining and rationalizing what databases were used and how they were searched. It also means describing how literature tracking was conducted and grey literature was searched. In the end, the decision to cease searching also needs to be fully explained and rationalized. Predetermined linear search strategies are unlikely to generate search results that are adequate for purposes of conducting knowledge-building and theory-generating qualitative systematic reviews. Instead, it is recommended that iterative search strategies take shape as reviews evolve. © 2012 Blackwell Publishing Ltd.

  14. Evaluation of hospital staff’s perceived quality of librarian-mediated literature searching services

    Directory of Open Access Journals (Sweden)

    Sandra McKeown, MLIS

    2017-04-01

    Conclusions: Our results demonstrate the limitations of written communication in the context of librarian-mediated literature searching and suggest a multifaceted approach to quality improvement efforts.

  15. Auditory Workload Assessment. Volume II: Non-Copyrighted Literature Search Results

    National Research Council Canada - National Science Library

    Rench, Michael

    2000-01-01

    In support of the US Army Research Laboratory, Human Research and Engineering Directorate, HSIAC, the Human Systems Information Analysis Center, conducted an extensive search of scientific literature...

  16. Nitrogen-15 reference book: medicine and biosciences

    International Nuclear Information System (INIS)

    Faust, H.

    1983-04-01

    A comprehensive bibliography on the application of the stable nitrogen isotope 15 N in medicine, animal nutrition and physiology, biosciences, and related disciplines is presented. The literature pertaining to this paper covers the period from 1977 to 1981. The references are completed by an index of all authors and a subject index with special emphasis to the used organisms, labelled compounds, and tracer techniques, respectively. (author)

  17. Has bioscience reconciled mind and body?

    Science.gov (United States)

    Davies, Carmel; Redmond, Catherine; Toole, Sinead O; Coughlan, Barbara

    2016-09-01

    The aim of this discursive paper is to explore the question 'has biological science reconciled mind and body?'. This paper has been inspired by the recognition that bioscience has a historical reputation for privileging the body over the mind. The disregard for the mind (emotions and behaviour) cast bioscience within a 'mind-body problem' paradigm. It has also led to inherent limitations in its capacity to contribute to understanding the complex nature of health. This is a discursive paper. Literature from the history and sociology of science and psychoneuroimmunology (1975-2015) inform the arguments in this paper. The historical and sociological literature provides the basis for a socio-cultural debate on mind-body considerations in science since the 1970s. The psychoneuroimmunology literature draws on mind-body bioscientific theory as a way to demonstrate how science is reconciling mind and body and advancing its understanding of the interconnections between emotions, behaviour and health. Using sociological and biological evidence, this paper demonstrates how bioscience is embracing and advancing its understanding of mind-body interconnectedness. It does this by demonstrating the emotional and behavioural alterations that are caused by two common phenomena; prolonged, chronic peripheral inflammation and prolonged psychological stress. The evidence and arguments provided has global currency that advances understanding of the inter-relationship between emotions, behaviour and health. This paper shows how bioscience has reconciled mind and body. In doing so, it has advanced an understanding of science's contribution to the inter-relationship between emotions, behaviour and health. The biological evidence supporting mind-body science has relevance to clinical practice for nurses and other healthcare professions. This paper discusses how this evidence can inform and enhance clinical practice directly and through research, education and policy. © 2015 John Wiley

  18. Automated Literature Searches for Longitudinal Tracking of Cancer Research Training Program Graduates.

    Science.gov (United States)

    Padilla, Luz A; Desmond, Renee A; Brooks, C Michael; Waterbor, John W

    2018-06-01

    A key outcome measure of cancer research training programs is the number of cancer-related peer-reviewed publications after training. Because program graduates do not routinely report their publications, staff must periodically conduct electronic literature searches on each graduate. The purpose of this study is to compare findings of an innovative computer-based automated search program versus repeated manual literature searches to identify post-training peer-reviewed publications. In late 2014, manual searches for publications by former R25 students identified 232 cancer-related articles published by 112 of 543 program graduates. In 2016, a research assistant was instructed in performing Scopus literature searches for comparison with individual PubMed searches on our 543 program graduates. Through 2014, Scopus found 304 cancer publications, 220 of that had been retrieved manually plus an additional 84 papers. However, Scopus missed 12 publications found manually. Together, both methods found 316 publications. The automated method found 96.2 % of the 316 publications while individual searches found only 73.4 %. An automated search method such as using the Scopus database is a key tool for conducting comprehensive literature searches, but it must be supplemented with periodic manual searches to find the initial publications of program graduates. A time-saving feature of Scopus is the periodic automatic alerts of new publications. Although a training period is needed and initial costs can be high, an automated search method is worthwhile due to its high sensitivity and efficiency in the long term.

  19. How to search for and use 'grey literature' in research.

    Science.gov (United States)

    Coad, Jane; Hardicre, Jayne; Devitt, Patric

    An ever-growing amount of grey literature is available to nurses, including oral presentations, personal communication, leaflets, newspapers and magazines, unpublished research, internal reports and minutes of meetings. It can be an invaluable research resource.

  20. A Literature Review of Indexing and Searching Techniques Implementation in Educational Search Engines

    Science.gov (United States)

    El Guemmat, Kamal; Ouahabi, Sara

    2018-01-01

    The objective of this article is to analyze the searching and indexing techniques of educational search engines' implementation while treating future challenges. Educational search engines could greatly help in the effectiveness of e-learning if used correctly. However, these engines have several gaps which influence the performance of e-learning…

  1. Television for Effective Parenthood; Literature Search and Existing Materials Assessment.

    Science.gov (United States)

    Appalachia Educational Lab., Charleston, WV.

    Materials concerning parenthood education were assessed and classified as published research, audiovisual materials, and pamphlets and booklets. Eighty-nine items of related research were reviewed and listed in a bibliography. Content and technical quality of audiovisual materials from a national search were reviewed and evaluated based on…

  2. Literature in Focus: "Axions: Theory, Cosmology, and Experimental Searches"

    CERN Document Server

    2009-01-01

    Axions are peculiar hypothetical particles that could both solve the CP problem of quantum chromodynamics and at the same time account for the dark matter of the universe. Based on a series of lectures by world experts in this field held at CERN, this volume provides a pedagogical introduction to the theory, cosmology and astrophysics of these fascinating particles and gives an up-to-date account of the status and prospect of ongoing and planned experimental searches. Learners and practitioners of astroparticle physics will find in this book both a concise introduction and a current reference work to a showcase topic that connects the "inner space" of the elementary particle world with the "outer space" of the universe at large. The book will be presented by Markus Kuster. "Axions: Theory, Cosmology, and Experimental Searches", edited by M. Kuster (Technische Universität Darmstadt), G. Raffelt (Max-Planck-Institu...

  3. Searching for Bill and Jane: Electronic Full-Text Literature.

    Science.gov (United States)

    Still, Julie; Kassabian, Vibiana

    1998-01-01

    Examines electronic full-text literature available on the World Wide Web and on CD-ROM. Discusses authors and genres, electronic texts, and fees. Highlights Shakespeare, Jane Austen, and nature writing. Provides a bibliography of Web guides, specialized Shakespeare pages, and pages dealing with the Shakespeare authorship debate and secondary…

  4. Google Scholar as replacement for systematic literature searches: good relative recall and precision are not enough.

    Science.gov (United States)

    Boeker, Martin; Vach, Werner; Motschall, Edith

    2013-10-26

    Recent research indicates a high recall in Google Scholar searches for systematic reviews. These reports raised high expectations of Google Scholar as a unified and easy to use search interface. However, studies on the coverage of Google Scholar rarely used the search interface in a realistic approach but instead merely checked for the existence of gold standard references. In addition, the severe limitations of the Google Search interface must be taken into consideration when comparing with professional literature retrieval tools.The objectives of this work are to measure the relative recall and precision of searches with Google Scholar under conditions which are derived from structured search procedures conventional in scientific literature retrieval; and to provide an overview of current advantages and disadvantages of the Google Scholar search interface in scientific literature retrieval. General and MEDLINE-specific search strategies were retrieved from 14 Cochrane systematic reviews. Cochrane systematic review search strategies were translated to Google Scholar search expression as good as possible under consideration of the original search semantics. The references of the included studies from the Cochrane reviews were checked for their inclusion in the result sets of the Google Scholar searches. Relative recall and precision were calculated. We investigated Cochrane reviews with a number of included references between 11 and 70 with a total of 396 references. The Google Scholar searches resulted in sets between 4,320 and 67,800 and a total of 291,190 hits. The relative recall of the Google Scholar searches had a minimum of 76.2% and a maximum of 100% (7 searches). The precision of the Google Scholar searches had a minimum of 0.05% and a maximum of 0.92%. The overall relative recall for all searches was 92.9%, the overall precision was 0.13%. The reported relative recall must be interpreted with care. It is a quality indicator of Google Scholar confined to

  5. SciRide Finder: a citation-based paradigm in biomedical literature search.

    Science.gov (United States)

    Volanakis, Adam; Krawczyk, Konrad

    2018-04-18

    There are more than 26 million peer-reviewed biomedical research items according to Medline/PubMed. This breadth of information is indicative of the progress in biomedical sciences on one hand, but an overload for scientists performing literature searches on the other. A major portion of scientific literature search is to find statements, numbers and protocols that can be cited to build an evidence-based narrative for a new manuscript. Because science builds on prior knowledge, such information has likely been written out and cited in an older manuscript. Thus, Cited Statements, pieces of text from scientific literature supported by citing other peer-reviewed publications, carry significant amount of condensed information on prior art. Based on this principle, we propose a literature search service, SciRide Finder (finder.sciride.org), which constrains the search corpus to such Cited Statements only. We demonstrate that Cited Statements can carry different information to this found in titles/abstracts and full text, giving access to alternative literature search results than traditional search engines. We further show how presenting search results as a list of Cited Statements allows researchers to easily find information to build an evidence-based narrative for their own manuscripts.

  6. An Analysis of Literature Searching Anxiety in Evidence-Based Medicine Education

    Directory of Open Access Journals (Sweden)

    Hui-Chin Chang

    2014-01-01

    Full Text Available Introduction. Evidence-Based Medicine (EBM is hurtling towards a cornerstone in lifelong learning for healthcare personnel worldwide. This study aims to evaluate the literature searching anxiety in graduate students in practicing EBM. Method The study participants were 48 graduate students who enrolled the EBM course at aMedical Universityin central Taiwan. Student’s t-test, Pearson correlation and multivariate regression, interviewing are used to evaluate the students’ literature searching anxiety of EBM course. The questionnaire is Literature Searching Anxiety Rating Scale -LSARS. Results The sources of anxiety are uncertainty of database selection, literatures evaluation and selection, technical assistance request, computer programs use, English and EBM education programs were disclosed. The class performance is negatively related to LSARS score, however, the correlation is statistically insignificant with the adjustment of gender, degree program, age category and experience of publication. Conclusion This study helps in understanding the causes and the extent of anxiety in order to work on a better teaching program planning to improve user’s searching skills and the capability of utilization the information; At the same time, provide friendly-user facilities of evidence searching. In short, we need to upgrade the learner’s searching 45 skills and reduce theanxiety. We also need to stress on the auxiliary teaching program for those with the prevalent and profoundanxiety during literature searching.

  7. MOMFER: A Search Engine of Thompson's Motif-Index of Folk Literature

    NARCIS (Netherlands)

    Karsdorp, F.B.; van der Meulen, Marten; Meder, Theo; van den Bosch, Antal

    2015-01-01

    More than fifty years after the first edition of Thompson's seminal Motif-Indexof Folk Literature, we present an online search engine tailored to fully disclose the index digitally. This search engine, called MOMFER, greatly enhances the searchability of the Motif-Index and provides exciting new

  8. Managing the Grey Literature of a Discipline through Collaboration: AgEcon Search

    Science.gov (United States)

    Kelly, Julia; Letnes, Louise

    2005-01-01

    AgEcon Search, http://www.agecon.lib.umn.edu, is an important and ground-breaking example of an alternative method of delivering current research results to many potential users. AgEcon Search, through a distributed model, collects and disseminates the grey literature of the fields of agricultural and resource economics. The development of this…

  9. Bioscience, bioinnovations, and bioethics.

    Science.gov (United States)

    Leisola, Matti

    2007-01-01

    Biosciences and their applications, which we call biotechnology, have affected human society in many ways. Great hopes have been set on future biotechnology. The future depends on three key issues. First, we need good science. Recent developments in biosciences have surprised us in many ways. I shall explain in this article how. Secondly, we need structured innovation systems in order to commercialize our discoveries. Europe is slow in this respect compared to our Japanese and American competitors and may lose in the competition. I shall describe the Finnish innovation chain using the rewarded Otaniemi model as an example of how commercialization can be done in a systematic way. Thirdly, we need norms to guide what to do and where to go. Bioethics is probably the most neglected of the three key issues. With modern biotechnology we are able to do things that should worry every citizen, but the ethical discussion has been largely neglected or the discussion in our pluralistic society is leading nowhere. I shall finally discuss these problems from a historical perspective.

  10. Literature search on the environmental impacts of tar sands operations

    International Nuclear Information System (INIS)

    Birkholz, D.; Prendergast, S.

    1990-09-01

    An extensive review is presented of the literature on the chemistry and biological impacts of current and potential effluents and discharges from oil sands plants on the Athabasca River. The pollutant compounds of interest included polycyclic aromatic hydrocarbons, methyl homologues and metabolites, polycyclic aromatic sulfur heterocycles, polycyclic aromatic nitrogen heterocycles, and naphthenic acids. Topics of interest include chemical methods for identifying and quantitating the above compounds and their metabolites, their sources and release rates, their toxicity to native fish of the Athabasca system, and their degradation in the natural environment. 376 refs., 4 figs., 26 tabs

  11. Literature search on risks related to ionizing radiations

    International Nuclear Information System (INIS)

    Abou Anoma, G.; Bijaoui, A.; Gauron, C.

    2013-09-01

    The authors propose a selection of information sources regarding risks related to ionizing radiations. They present knowledge bases which can be found on different Internet sites belonging to different bodies and agencies (IRSN, CEA, INRS, SFRP, CNRS, Radioprotection Cirkus, EDF) and in different books. They present information sources dealing with radionuclides which can be found in French and international Internet sites and in books, information sources concerning different professional activities and sectors (ASN, IRSN, INRS, medical-professional sheets proposed by the CISME, sheets proposed by the Labour Ministry and other bodies). It presents information sources dealing with radiological incidents, accidents and emergencies, dealing with radioactive wastes, with the legal European and French framework. Some additional tools of general or more detailed information are indicated (CIPR, IAEA, UNSCAR, IRPA, IRSN, SFRP, CEA, CEPN, Radiation Cirkus, books). Ways to get an updated search are indicated for different databases, as well as some practical services

  12. Semi-automating the manual literature search for systematic reviews increases efficiency.

    Science.gov (United States)

    Chapman, Andrea L; Morgan, Laura C; Gartlehner, Gerald

    2010-03-01

    To minimise retrieval bias, manual literature searches are a key part of the search process of any systematic review. Considering the need to have accurate information, valid results of the manual literature search are essential to ensure scientific standards; likewise efficient approaches that minimise the amount of personnel time required to conduct a manual literature search are of great interest. The objective of this project was to determine the validity and efficiency of a new manual search method that utilises the scopus database. We used the traditional manual search approach as the gold standard to determine the validity and efficiency of the proposed scopus method. Outcome measures included completeness of article detection and personnel time involved. Using both methods independently, we compared the results based on accuracy of the results, validity and time spent conducting the search, efficiency. Regarding accuracy, the scopus method identified the same studies as the traditional approach indicating its validity. In terms of efficiency, using scopus led to a time saving of 62.5% compared with the traditional approach (3 h versus 8 h). The scopus method can significantly improve the efficiency of manual searches and thus of systematic reviews.

  13. Evaluation of hospital staff's perceived quality of librarian-mediated literature searching services.

    Science.gov (United States)

    McKeown, Sandra; Konrad, Shauna-Lee; McTavish, Jill; Boyce, Erin

    2017-04-01

    The research evaluated the perceived quality of librarian-mediated literature searching services at one of Canada's largest acute care teaching hospitals for the purpose of continuous quality improvement and investigation of relationships between variables that can impact user satisfaction. An online survey was constructed using evidence-based methodologies. A systematic sample of staff and physicians requesting literature searches at London Health Sciences Centre were invited to participate in the study over a one-year period. Data analyses included descriptive statistics of closed-ended questions and coding of open-ended questions. A range of staff including clinicians, researchers, educators, leaders, and analysts submitted a total of 137 surveys, representing a response rate of 71%. Staff requested literature searches for the following "primary" purposes: research or publication (34%), teaching or training (20%), informing a policy or standard practice (16%), patient care (15%), and "other" purposes (15%). While the majority of staff (76%) submitted search requests using methods of written communication, including email and search request forms, staff using methods of verbal communication, including face-to-face and telephone conversations, were significantly more likely to be extremely satisfied with the librarian's interpretation of the search request ( p =0.004) and to rate the perceived quality of the search results as excellent ( p =0.005). In most cases, librarians followed up with staff to clarify the details of their search requests (72%), and these staff were significantly more likely to be extremely satisfied with the librarian's interpretation of the search request ( p =0.002). Our results demonstrate the limitations of written communication in the context of librarian-mediated literature searching and suggest a multifaceted approach to quality improvement efforts.

  14. Medical literature searches: a comparison of PubMed and Google Scholar.

    Science.gov (United States)

    Nourbakhsh, Eva; Nugent, Rebecca; Wang, Helen; Cevik, Cihan; Nugent, Kenneth

    2012-09-01

    Medical literature searches provide critical information for clinicians. However, the best strategy for identifying relevant high-quality literature is unknown. We compared search results using PubMed and Google Scholar on four clinical questions and analysed these results with respect to article relevance and quality. Abstracts from the first 20 citations for each search were classified into three relevance categories. We used the weighted kappa statistic to analyse reviewer agreement and nonparametric rank tests to compare the number of citations for each article and the corresponding journals' impact factors. Reviewers ranked 67.6% of PubMed articles and 80% of Google Scholar articles as at least possibly relevant (P = 0.116) with high agreement (all kappa P-values PubMed searches and Google Scholar searches often identify different articles. In this study, Google Scholar articles were more likely to be classified as relevant, had higher numbers of citations and were published in higher impact factor journals. The identification of frequently cited articles using Google Scholar for searches probably has value for initial literature searches. © 2012 The authors. Health Information and Libraries Journal © 2012 Health Libraries Group.

  15. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. DALE JAMIESON. Articles written in Journal of Biosciences. Volume 43 Issue 1 March 2018 pp 3-8 Commentary. Liberating primatology · SINDHU RADHAKRISHNA DALE JAMIESON · More Details Abstract Fulltext PDF ...

  16. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Vidita A Vaidya. Articles written in Journal of Biosciences. Volume 25 Issue 2 June 2000 pp 123-124. Clipboard: Stress, depression and hippocampal damage · Vidita A Vaidya · More Details Fulltext PDF ...

  17. Textpresso Central: a customizable platform for searching, text mining, viewing, and curating biomedical literature.

    Science.gov (United States)

    Müller, H-M; Van Auken, K M; Li, Y; Sternberg, P W

    2018-03-09

    The biomedical literature continues to grow at a rapid pace, making the challenge of knowledge retrieval and extraction ever greater. Tools that provide a means to search and mine the full text of literature thus represent an important way by which the efficiency of these processes can be improved. We describe the next generation of the Textpresso information retrieval system, Textpresso Central (TPC). TPC builds on the strengths of the original system by expanding the full text corpus to include the PubMed Central Open Access Subset (PMC OA), as well as the WormBase C. elegans bibliography. In addition, TPC allows users to create a customized corpus by uploading and processing documents of their choosing. TPC is UIMA compliant, to facilitate compatibility with external processing modules, and takes advantage of Lucene indexing and search technology for efficient handling of millions of full text documents. Like Textpresso, TPC searches can be performed using keywords and/or categories (semantically related groups of terms), but to provide better context for interpreting and validating queries, search results may now be viewed as highlighted passages in the context of full text. To facilitate biocuration efforts, TPC also allows users to select text spans from the full text and annotate them, create customized curation forms for any data type, and send resulting annotations to external curation databases. As an example of such a curation form, we describe integration of TPC with the Noctua curation tool developed by the Gene Ontology (GO) Consortium. Textpresso Central is an online literature search and curation platform that enables biocurators and biomedical researchers to search and mine the full text of literature by integrating keyword and category searches with viewing search results in the context of the full text. It also allows users to create customized curation interfaces, use those interfaces to make annotations linked to supporting evidence statements

  18. Introducing PALETTE: an iterative method for conducting a literature search for a review in palliative care.

    Science.gov (United States)

    Zwakman, Marieke; Verberne, Lisa M; Kars, Marijke C; Hooft, Lotty; van Delden, Johannes J M; Spijker, René

    2018-06-02

    In the rapidly developing specialty of palliative care, literature reviews have become increasingly important to inform and improve the field. When applying widely used methods for literature reviews developed for intervention studies onto palliative care, challenges are encountered such as the heterogeneity of palliative care in practice (wide range of domains in patient characteristics, stages of illness and stakeholders), the explorative character of review questions, and the poorly defined keywords and concepts. To overcome the challenges and to provide guidance for researchers to conduct a literature search for a review in palliative care, Palliative cAre Literature rEview iTeraTive mEthod (PALLETE), a pragmatic framework, was developed. We assessed PALETTE with a detailed description. PALETTE consists of four phases; developing the review question, building the search strategy, validating the search strategy and performing the search. The framework incorporates different information retrieval techniques: contacting experts, pearl growing, citation tracking and Boolean searching in a transparent way to maximize the retrieval of literature relevant to the topic of interest. The different components and techniques are repeated until no new articles are qualified for inclusion. The phases within PALETTE are interconnected by a recurrent process of validation on 'golden bullets' (articles that undoubtedly should be part of the review), citation tracking and concept terminology reflecting the review question. To give insight in the value of PALETTE, we compared PALETTE with the recommended search method for reviews of intervention studies. By using PALETTE on two palliative care literature reviews, we were able to improve our review questions and search strategies. Moreover, in comparison with the recommended search for intervention reviews, the number of articles needed to be screened was decreased whereas more relevant articles were retrieved. Overall, PALETTE

  19. Automatic figure ranking and user interfacing for intelligent figure search.

    Directory of Open Access Journals (Sweden)

    Hong Yu

    2010-10-01

    Full Text Available Figures are important experimental results that are typically reported in full-text bioscience articles. Bioscience researchers need to access figures to validate research facts and to formulate or to test novel research hypotheses. On the other hand, the sheer volume of bioscience literature has made it difficult to access figures. Therefore, we are developing an intelligent figure search engine (http://figuresearch.askhermes.org. Existing research in figure search treats each figure equally, but we introduce a novel concept of "figure ranking": figures appearing in a full-text biomedical article can be ranked by their contribution to the knowledge discovery.We empirically validated the hypothesis of figure ranking with over 100 bioscience researchers, and then developed unsupervised natural language processing (NLP approaches to automatically rank figures. Evaluating on a collection of 202 full-text articles in which authors have ranked the figures based on importance, our best system achieved a weighted error rate of 0.2, which is significantly better than several other baseline systems we explored. We further explored a user interfacing application in which we built novel user interfaces (UIs incorporating figure ranking, allowing bioscience researchers to efficiently access important figures. Our evaluation results show that 92% of the bioscience researchers prefer as the top two choices the user interfaces in which the most important figures are enlarged. With our automatic figure ranking NLP system, bioscience researchers preferred the UIs in which the most important figures were predicted by our NLP system than the UIs in which the most important figures were randomly assigned. In addition, our results show that there was no statistical difference in bioscience researchers' preference in the UIs generated by automatic figure ranking and UIs by human ranking annotation.The evaluation results conclude that automatic figure ranking and user

  20. Searching for religion and mental health studies required health, social science, and grey literature databases.

    Science.gov (United States)

    Wright, Judy M; Cottrell, David J; Mir, Ghazala

    2014-07-01

    To determine the optimal databases to search for studies of faith-sensitive interventions for treating depression. We examined 23 health, social science, religious, and grey literature databases searched for an evidence synthesis. Databases were prioritized by yield of (1) search results, (2) potentially relevant references identified during screening, (3) included references contained in the synthesis, and (4) included references that were available in the database. We assessed the impact of databases beyond MEDLINE, EMBASE, and PsycINFO by their ability to supply studies identifying new themes and issues. We identified pragmatic workload factors that influence database selection. PsycINFO was the best performing database within all priority lists. ArabPsyNet, CINAHL, Dissertations and Theses, EMBASE, Global Health, Health Management Information Consortium, MEDLINE, PsycINFO, and Sociological Abstracts were essential for our searches to retrieve the included references. Citation tracking activities and the personal library of one of the research teams made significant contributions of unique, relevant references. Religion studies databases (Am Theo Lib Assoc, FRANCIS) did not provide unique, relevant references. Literature searches for reviews and evidence syntheses of religion and health studies should include social science, grey literature, non-Western databases, personal libraries, and citation tracking activities. Copyright © 2014 Elsevier Inc. All rights reserved.

  1. Literatura chicana: Vida en busca de forma (Chicano Literature: Life in Search of Form).

    Science.gov (United States)

    Rivera, Tomas

    The Chicano culture is searching for appropriate expression in art forms and literature. The Chicano novel and essay, often written in English, seem directed toward the North American public. The short story is the most varied in viewpoint and most versatile in form. Poetry captures the Chicano sensitivity. It is almost impossible to note the…

  2. Environmental Biosciences Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2007-01-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the DOE. Plans for restructuring the performance schedule of the trichloroethylene projects have been submitted to the department. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this

  3. Brazilian academic search filter: application to the scientific literature on physical activity.

    Science.gov (United States)

    Sanz-Valero, Javier; Ferreira, Marcos Santos; Castiel, Luis David; Wanden-Berghe, Carmina; Guilam, Maria Cristina Rodrigues

    2010-10-01

    To develop a search filter in order to retrieve scientific publications on physical activity from Brazilian academic institutions. The academic search filter consisted of the descriptor "exercise" associated through the term AND, to the names of the respective academic institutions, which were connected by the term OR. The MEDLINE search was performed with PubMed on 11/16/2008. The institutions were selected according to the classification from the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) for interuniversity agreements. A total of 407 references were retrieved, corresponding to about 0.9% of all articles about physical activity and 0.5% of the Brazilian academic publications indexed in MEDLINE on the search date. When compared with the manual search undertaken, the search filter (descriptor + institutional filter) showed a sensitivity of 99% and a specificity of 100%. The institutional search filter showed high sensitivity and specificity, and is applicable to other areas of knowledge in health sciences. It is desirable that every Brazilian academic institution establish its "standard name/brand" in order to efficiently retrieve their scientific literature.

  4. PubMed and beyond: a survey of web tools for searching biomedical literature

    Science.gov (United States)

    Lu, Zhiyong

    2011-01-01

    The past decade has witnessed the modern advances of high-throughput technology and rapid growth of research capacity in producing large-scale biological data, both of which were concomitant with an exponential growth of biomedical literature. This wealth of scholarly knowledge is of significant importance for researchers in making scientific discoveries and healthcare professionals in managing health-related matters. However, the acquisition of such information is becoming increasingly difficult due to its large volume and rapid growth. In response, the National Center for Biotechnology Information (NCBI) is continuously making changes to its PubMed Web service for improvement. Meanwhile, different entities have devoted themselves to developing Web tools for helping users quickly and efficiently search and retrieve relevant publications. These practices, together with maturity in the field of text mining, have led to an increase in the number and quality of various Web tools that provide comparable literature search service to PubMed. In this study, we review 28 such tools, highlight their respective innovations, compare them to the PubMed system and one another, and discuss directions for future development. Furthermore, we have built a website dedicated to tracking existing systems and future advances in the field of biomedical literature search. Taken together, our work serves information seekers in choosing tools for their needs and service providers and developers in keeping current in the field. Database URL: http://www.ncbi.nlm.nih.gov/CBBresearch/Lu/search PMID:21245076

  5. PubMed and beyond: a survey of web tools for searching biomedical literature.

    Science.gov (United States)

    Lu, Zhiyong

    2011-01-01

    The past decade has witnessed the modern advances of high-throughput technology and rapid growth of research capacity in producing large-scale biological data, both of which were concomitant with an exponential growth of biomedical literature. This wealth of scholarly knowledge is of significant importance for researchers in making scientific discoveries and healthcare professionals in managing health-related matters. However, the acquisition of such information is becoming increasingly difficult due to its large volume and rapid growth. In response, the National Center for Biotechnology Information (NCBI) is continuously making changes to its PubMed Web service for improvement. Meanwhile, different entities have devoted themselves to developing Web tools for helping users quickly and efficiently search and retrieve relevant publications. These practices, together with maturity in the field of text mining, have led to an increase in the number and quality of various Web tools that provide comparable literature search service to PubMed. In this study, we review 28 such tools, highlight their respective innovations, compare them to the PubMed system and one another, and discuss directions for future development. Furthermore, we have built a website dedicated to tracking existing systems and future advances in the field of biomedical literature search. Taken together, our work serves information seekers in choosing tools for their needs and service providers and developers in keeping current in the field. Database URL: http://www.ncbi.nlm.nih.gov/CBBresearch/Lu/search.

  6. BEST: Next-Generation Biomedical Entity Search Tool for Knowledge Discovery from Biomedical Literature.

    Directory of Open Access Journals (Sweden)

    Sunwon Lee

    Full Text Available As the volume of publications rapidly increases, searching for relevant information from the literature becomes more challenging. To complement standard search engines such as PubMed, it is desirable to have an advanced search tool that directly returns relevant biomedical entities such as targets, drugs, and mutations rather than a long list of articles. Some existing tools submit a query to PubMed and process retrieved abstracts to extract information at query time, resulting in a slow response time and limited coverage of only a fraction of the PubMed corpus. Other tools preprocess the PubMed corpus to speed up the response time; however, they are not constantly updated, and thus produce outdated results. Further, most existing tools cannot process sophisticated queries such as searches for mutations that co-occur with query terms in the literature. To address these problems, we introduce BEST, a biomedical entity search tool. BEST returns, as a result, a list of 10 different types of biomedical entities including genes, diseases, drugs, targets, transcription factors, miRNAs, and mutations that are relevant to a user's query. To the best of our knowledge, BEST is the only system that processes free text queries and returns up-to-date results in real time including mutation information in the results. BEST is freely accessible at http://best.korea.ac.kr.

  7. [Titanium or steel as osteosynthesis material : Systematic literature search for clinical evidence].

    Science.gov (United States)

    Joeris, Alexander; Goldhahn, Sabine; Rometsch, Elke; Höntzsch, Dankward

    2017-02-01

    The selection of the appropriate implant material, stainless steel or titanium, is still the decision of the surgeon and/or the affiliated institution. Additionally, remarkable international differences can be found between the different markets, which cannot really be explained. A systematic literature search was performed to verify whether there is clinical evidence for the preference of one material over the other. The systematic literature search was performed utilizing the internet databases PubMed, Cochrane and Web of Science. Comparative studies were included that reported on adult patients with osteosynthesis of extremities after trauma using either stainless steel or titanium implants. Information was extracted about infection rates, incidence of clinically relevant allergies, problems with implant removal and other complications. A total of 18 publications were identified to be eligible and 2 referenced articles were added. In summary, there is insufficient clinical evidence that the use of titanium or steel implants has a positive or negative effect on fracture healing, shows different rates of allergies, different rates of infections or mechanical failure. No supporting evidence could be identified for the difficulties with removal of titanium implants reported by surgeons. This systematic literature search did not provide any clinical evidence for material-related differences between titanium or stainless steel implants for fracture fixation. Based on the current clinical evidence both titanium and steel implants can be considered to be of equal value. The reported difficulties with implant removal are not reflected in the published literature.

  8. Literature search strategies for interdisciplinary research a sourcebook for scientists and engineers

    CERN Document Server

    Ackerson, Linda G

    2006-01-01

    The amount of published literature can be overwhelming for scientists and researchers moving from a broad disciplinary research area to a more specialized one, particularly in fields that use information from more than one discipline. Without a focused inquiry, the researcher may find too little information or may be overcome by too much. Striking the correct balance of information is the focus of Literature Search Strategies for Interdisciplinary Research. This useful reference tool studies diverse interdisciplinary areas revealing the general and individual qualities that dictate the strateg

  9. Beyond PubMed: Searching the "Grey Literature" for Clinical Trial Results.

    Science.gov (United States)

    Citrome, Leslie

    2014-07-01

    Clinical trial results have been traditionally communicated through the publication of scholarly reports and reviews in biomedical journals. However, this dissemination of information can be delayed or incomplete, making it difficult to appraise new treatments, or in the case of missing data, evaluate older interventions. Going beyond the routine search of PubMed, it is possible to discover additional information in the "grey literature." Examples of the grey literature include clinical trial registries, patent databases, company and industrywide repositories, regulatory agency digital archives, abstracts of paper and poster presentations on meeting/congress websites, industry investor reports and press releases, and institutional and personal websites.

  10. Literature search on Light Water Reactor (LWR) fuel and absorber rod fabrication, 1960--1976

    International Nuclear Information System (INIS)

    Sample, C.R.

    1977-02-01

    A literature search was conducted to provide information supporting the design of a conceptual Light Water Reactor (LWR) Fuel Fabrication plant. Emphasis was placed on fuel processing and pin bundle fabrication, effects of fuel impurities and microstructure on performance and densification, quality assurance, absorber and poison rod fabrication, and fuel pin welding. All data have been taken from publicly available documents, journals, and books. This work was sponsored by the Finishing Processes-Mixed Oxide (MOX) Fuel Fabrication Studies program at HEDL

  11. Literature search on Light Water Reactor (LWR) fuel and absorber rod fabrication, 1960--1976

    Energy Technology Data Exchange (ETDEWEB)

    Sample, C R [comp.

    1977-02-01

    A literature search was conducted to provide information supporting the design of a conceptual Light Water Reactor (LWR) Fuel Fabrication plant. Emphasis was placed on fuel processing and pin bundle fabrication, effects of fuel impurities and microstructure on performance and densification, quality assurance, absorber and poison rod fabrication, and fuel pin welding. All data have been taken from publicly available documents, journals, and books. This work was sponsored by the Finishing Processes-Mixed Oxide (MOX) Fuel Fabrication Studies program at HEDL.

  12. Finding "hard to find" literature on hard to find groups: A novel technique to search grey literature on refugees and asylum seekers.

    Science.gov (United States)

    Enticott, Joanne; Buck, Kimberly; Shawyer, Frances

    2018-03-01

    There is a lack of information on how to execute effective searches of the grey literature on refugee and asylum seeker groups for inclusion in systematic reviews. High-quality government reports and other grey literature relevant to refugees may not always be identified in conventional literature searches. During the process of conducting a recent systematic review, we developed a novel strategy for systematically searching international refugee and asylum seeker-related grey literature. The approach targets governmental health departments and statistical agencies, who have considerable access to refugee and asylum seeker populations for research purposes but typically do not publish findings in academic forums. Compared to a conventional grey literature search strategy, our novel technique yielded an eightfold increase in relevant high-quality grey sources that provided valuable content in informing our review. Incorporating a search of the grey literature into systematic reviews of refugee and asylum seeker research is essential to providing a more complete view of the evidence. Our novel strategy offers a practical and feasible method of conducting systematic grey literature searches that may be adaptable to a range of research questions, contexts, and resource constraints. Copyright © 2017 John Wiley & Sons, Ltd.

  13. Grey Literature Searching for Health Sciences Systematic Reviews: A Prospective Study of Time Spent and Resources Utilized.

    Science.gov (United States)

    Saleh, Ahlam A; Ratajeski, Melissa A; Bertolet, Marnie

    To identify estimates of time taken to search grey literature in support of health sciences systematic reviews and to identify searcher or systematic review characteristics that may impact resource selection or time spent searching. A survey was electronically distributed to searchers embarking on a new systematic review. Characteristics of the searcher and systematic review were collected along with time spent searching and what resources were searched. Time and resources were tabulated and resources were categorized as grey or non-grey. Data was analyzed using Kruskal-Wallis tests. Out of 81 original respondents, 21% followed through with completion of the surveys in their entirety. The median time spent searching all resources was 471 minutes, and of those a median of 85 minutes were spent searching grey literature. The median number of resources used in a systematic review search was four and the median number of grey literature sources searched was two. The amount of time spent searching was influenced by whether the systematic review was grant funded. Additionally, the number of resources searched was impacted by institution type and whether systematic review training was received. This study characterized the amount of time for conducting systematic review searches including searching the grey literature, in addition to the number and types of resources used. This may aid searchers in planning their time, along with providing benchmark information for future studies. This paper contributes by quantifying current grey literature search patterns and associating them with searcher and review characteristics. Further discussion and research into the search approach for grey literature in support of systematic reviews is encouraged.

  14. Risk factors for bladder cancer: challenges of conducting a literature search using PubMed.

    Science.gov (United States)

    Joshi, Ashish; Preslan, Elicia

    2011-04-01

    The objective of this study was to assess the risk factors for bladder cancer using PubMed articles from January 2000 to December 2009. The study also aimed to describe the challenges encountered in the methodology of a literature search for bladder cancer risk factors using PubMed. Twenty-six categories of risk factors for bladder cancer were identified using the National Cancer Institute Web site and the Medical Subject Headings (MeSH) Web site. A total of 1,338 PubMed searches were run using the term "urinary bladder cancer" and a risk factor term (e.g., "cigarette smoking") and were screened to identify 260 articles for final analysis. The search strategy had an overall precision of 3.42 percent, relative recall of 12.64 percent, and an F-measure of 5.39 percent. Although search terms derived from MeSH had the highest overall precision and recall, the differences did not reach significance, which indicates that for generalized, free-text searches of the PubMed database, the searchers' own terms are generally as effective as MeSH terms.

  15. MememxGATE: Unearthing Latent Content Features for Improved Search and Relevancy Ranking Across Scientific Literature

    Science.gov (United States)

    Wilson, B. D.; McGibbney, L. J.; Mattmann, C. A.; Ramirez, P.; Joyce, M.; Whitehall, K. D.

    2015-12-01

    Quantifying scientific relevancy is of increasing importance to NASA and the research community. Scientific relevancy may be defined by mapping the impacts of a particular NASA mission, instrument, and/or retrieved variables to disciplines such as climate predictions, natural hazards detection and mitigation processes, education, and scientific discoveries. Related to relevancy, is the ability to expose data with similar attributes. This in turn depends upon the ability for us to extract latent, implicit document features from scientific data and resources and make them explicit, accessible and useable for search activities amongst others. This paper presents MemexGATE; a server side application, command line interface and computing environment for running large scale metadata extraction, general architecture text engineering, document classification and indexing tasks over document resources such as social media streams, scientific literature archives, legal documentation, etc. This work builds on existing experiences using MemexGATE (funded, developed and validated through the DARPA Memex Progrjam PI Mattmann) for extracting and leveraging latent content features from document resources within the Materials Research domain. We extend the software functionality capability to the domain of scientific literature with emphasis on the expansion of gazetteer lists, named entity rules, natural language construct labeling (e.g. synonym, antonym, hyponym, etc.) efforts to enable extraction of latent content features from data hosted by wide variety of scientific literature vendors (AGU Meeting Abstract Database, Springer, Wiley Online, Elsevier, etc.) hosting earth science literature. Such literature makes both implicit and explicit references to NASA datasets and relationships between such concepts stored across EOSDIS DAAC's hence we envisage that a significant part of this effort will also include development and understanding of relevancy signals which can ultimately

  16. Complementary Value of Databases for Discovery of Scholarly Literature: A User Survey of Online Searching for Publications in Art History

    Science.gov (United States)

    Nemeth, Erik

    2010-01-01

    Discovery of academic literature through Web search engines challenges the traditional role of specialized research databases. Creation of literature outside academic presses and peer-reviewed publications expands the content for scholarly research within a particular field. The resulting body of literature raises the question of whether scholars…

  17. Searching and synthesising 'grey literature' and 'grey information' in public health: critical reflections on three case studies.

    Science.gov (United States)

    Adams, Jean; Hillier-Brown, Frances C; Moore, Helen J; Lake, Amelia A; Araujo-Soares, Vera; White, Martin; Summerbell, Carolyn

    2016-09-29

    Grey literature includes a range of documents not controlled by commercial publishing organisations. This means that grey literature can be difficult to search and retrieve for evidence synthesis. Much knowledge and evidence in public health, and other fields, accumulates from innovation in practice. This knowledge may not even be of sufficient formality to meet the definition of grey literature. We term this knowledge 'grey information'. Grey information may be even harder to search for and retrieve than grey literature. On three previous occasions, we have attempted to systematically search for and synthesise public health grey literature and information-both to summarise the extent and nature of particular classes of interventions and to synthesise results of evaluations. Here, we briefly describe these three 'case studies' but focus on our post hoc critical reflections on searching for and synthesising grey literature and information garnered from our experiences of these case studies. We believe these reflections will be useful to future researchers working in this area. Issues discussed include search methods, searching efficiency, replicability of searches, data management, data extraction, assessing study 'quality', data synthesis, time and resources, and differentiating evidence synthesis from primary research. Information on applied public health research questions relating to the nature and range of public health interventions, as well as many evaluations of these interventions, may be predominantly, or only, held in grey literature and grey information. Evidence syntheses on these topics need, therefore, to embrace grey literature and information. Many typical systematic review methods for searching, appraising, managing, and synthesising the evidence base can be adapted for use with grey literature and information. Evidence synthesisers should carefully consider the opportunities and problems offered by including grey literature and information

  18. A systematic literature search on psychological first aid: lack of evidence to develop guidelines.

    Science.gov (United States)

    Dieltjens, Tessa; Moonens, Inge; Van Praet, Koen; De Buck, Emmy; Vandekerckhove, Philippe

    2014-01-01

    Providing psychological first aid (PFA) is generally considered to be an important element in preliminary care of disaster victims. Using the best available scientific basis for courses and educational materials, the Belgian Red Cross-Flanders wants to ensure that its volunteers are trained in the best way possible. To identify effective PFA practices, by systematically reviewing the evidence in existing guidelines, systematic reviews and individual studies. Systematic literature searches in five bibliographic databases (MEDLINE, PsycINFO, The Cochrane Library, PILOTS and G-I-N) were conducted from inception to July 2013. Five practice guidelines were included which were found to vary in the development process (AGREE II score 20-53%) and evidence base used. None of them provides solid evidence concerning the effectiveness of PFA practices. Additionally, two systematic reviews of PFA were found, both noting a lack of studies on PFA. A complementary search for individual studies, using a more sensitive search strategy, identified 11 237 references of which 102 were included for further full-text examination, none of which ultimately provides solid evidence concerning the effectiveness of PFA practices. The scientific literature on psychological first aid available to date, does not provide any evidence about the effectiveness of PFA interventions. Currently it is impossible to make evidence-based guidelines about which practices in psychosocial support are most effective to help disaster and trauma victims.

  19. A systematic literature search on psychological first aid: lack of evidence to develop guidelines.

    Directory of Open Access Journals (Sweden)

    Tessa Dieltjens

    Full Text Available Providing psychological first aid (PFA is generally considered to be an important element in preliminary care of disaster victims. Using the best available scientific basis for courses and educational materials, the Belgian Red Cross-Flanders wants to ensure that its volunteers are trained in the best way possible.To identify effective PFA practices, by systematically reviewing the evidence in existing guidelines, systematic reviews and individual studies.Systematic literature searches in five bibliographic databases (MEDLINE, PsycINFO, The Cochrane Library, PILOTS and G-I-N were conducted from inception to July 2013.Five practice guidelines were included which were found to vary in the development process (AGREE II score 20-53% and evidence base used. None of them provides solid evidence concerning the effectiveness of PFA practices. Additionally, two systematic reviews of PFA were found, both noting a lack of studies on PFA. A complementary search for individual studies, using a more sensitive search strategy, identified 11 237 references of which 102 were included for further full-text examination, none of which ultimately provides solid evidence concerning the effectiveness of PFA practices.The scientific literature on psychological first aid available to date, does not provide any evidence about the effectiveness of PFA interventions. Currently it is impossible to make evidence-based guidelines about which practices in psychosocial support are most effective to help disaster and trauma victims.

  20. Literature search on Kickers and Septa for the Amsterdam Pulse Stretcher

    International Nuclear Information System (INIS)

    Kuijt, J.; Linden, A. v.d.

    1988-01-01

    Literature search has yielded a qualitative and quantitative view on kickers. Quantitatively specifications on designs in literature have been collected. The UPDATE-kickers have been given the following specs: deflection angle 2 mrad, pulsewidth 2 μs, falltime 70 ns, available length about 2 m. Undertaken is a comparison of characteristic parameters: kick strength (energy x angle), pulse characteristics (pulsewidth/falltime) and required peak power. Realisation of the pulse characteristics will impose the greatest requirements on the UPDATE-kicker design. The comparison has shown correspondence with two ferrite kicker designs (CERN-CPS and ELSA), the Los Alamos TEM-kicker and the electrostatic kicker from Saskatoon. On account of the relative simplicity of construction and pulse forming network the Saskatoon kicker has been chosen as the starting point for a design study. Design calculations will proceed from a length of 1.6 m and a gap of 4 cm between two parallel plates at a potential difference of 50 kV. Literature search on septa resulted in an overview on septum magnets and electrostatic wire septa. 72 refs.; 14 figs.; 2 tabs

  1. PubMed vs. HighWire Press: a head-to-head comparison of two medical literature search engines.

    Science.gov (United States)

    Vanhecke, Thomas E; Barnes, Michael A; Zimmerman, Janet; Shoichet, Sandor

    2007-09-01

    PubMed and HighWire Press are both useful medical literature search engines available for free to anyone on the internet. We measured retrieval accuracy, number of results generated, retrieval speed, features and search tools on HighWire Press and PubMed using the quick search features of each. We found that using HighWire Press resulted in a higher likelihood of retrieving the desired article and higher number of search results than the same search on PubMed. PubMed was faster than HighWire Press in delivering search results regardless of search settings. There are considerable differences in search features between these two search engines.

  2. Novel citation-based search method for scientific literature: application to meta-analyses.

    Science.gov (United States)

    Janssens, A Cecile J W; Gwinn, M

    2015-10-13

    Finding eligible studies for meta-analysis and systematic reviews relies on keyword-based searching as the gold standard, despite its inefficiency. Searching based on direct citations is not sufficiently comprehensive. We propose a novel strategy that ranks articles on their degree of co-citation with one or more "known" articles before reviewing their eligibility. In two independent studies, we aimed to reproduce the results of literature searches for sets of published meta-analyses (n = 10 and n = 42). For each meta-analysis, we extracted co-citations for the randomly selected 'known' articles from the Web of Science database, counted their frequencies and screened all articles with a score above a selection threshold. In the second study, we extended the method by retrieving direct citations for all selected articles. In the first study, we retrieved 82% of the studies included in the meta-analyses while screening only 11% as many articles as were screened for the original publications. Articles that we missed were published in non-English languages, published before 1975, published very recently, or available only as conference abstracts. In the second study, we retrieved 79% of included studies while screening half the original number of articles. Citation searching appears to be an efficient and reasonably accurate method for finding articles similar to one or more articles of interest for meta-analysis and reviews.

  3. A systematic literature search to identify performance measure outcomes used in clinical studies of racehorses.

    Science.gov (United States)

    Wylie, C E; Newton, J R

    2018-05-01

    Racing performance is often used as a measurable outcome variable in research studies investigating clinical diagnoses or interventions. However, the use of many different performance measures largely precludes conduct of meaningful comparative studies and, to date, those being used have not been collated. To systematically review the veterinary scientific literature for the use of racing performance as a measurable outcome variable in clinical studies of racehorses, collate and identify those most popular, and identify their advantages and disadvantages. Systematic literature search. The search criteria "((racing AND performance) AND (horses OR equidae))" were adapted for both MEDLINE and CAB Abstracts databases. Data were collected in standardised recording forms for binary, categorical and quantitative measures, and the use of performance indices. In total, 217 studies that described racing performance were identified, contributing 117 different performance measures. No one performance measure was used in all studies, despite 90.3% using more than one variable. Data regarding race starts and earnings were used most commonly, with 88.0% and 54.4% of studies including at least one measure of starts and earnings, respectively. Seventeen variables were used 10 times or more, with the top five comprising: 'return to racing', 'number of starts', 'days to first start', 'earnings per period of time' and 'earnings per start'. The search strategies may not have identified all relevant papers, introducing bias to the review. Performance indices have been developed to improve assessment of interventions; however, they are not widely adopted in the scientific literature. Use of the two most commonly identified measures, whether the horse returned to racing and number of starts over a defined period of time, would best facilitate future systematic reviews and meta-analyses in advance of the development of a gold-standard measure of race performance outcome. © 2017 EVJ Ltd.

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    Home; Journals; Journal of Biosciences. Anil K Gupta. Articles written in Journal of Biosciences. Volume 27 Issue 7 December 2002 pp 703-714 Review Article. Applications of inulin and oligofructose in health and nutrition · Narinder Kaur Anil K Gupta · More Details Abstract Fulltext PDF. Inulin and oligofructose belong to a ...

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    Home; Journals; Journal of Biosciences. Urvashi Bahadur. Articles written in Journal of Biosciences. Volume 26 Issue 1 March 2001 pp 39-46 Articles. Characterization of chicken riboflavin carrier protein gene structure and promoter regulation by estrogen · Nandini Vasudevan Urvashi Bahadur Paturu Kondaiah.

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    Home; Journals; Journal of Biosciences. Sebastian Fettig. Articles written in Journal of Biosciences. Volume 32 Issue 3 April 2007 pp 501-510 Articles. specific and unspecific responses of plants to cold and drought stress · Erwin H Beck Sebastian Fettig Claudia Knake Katja Hartig Tribikram Bhattarai · More Details Abstract ...

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    Home; Journals; Journal of Biosciences. Odir A Dellagostin. Articles written in Journal of Biosciences. Volume 33 Issue 3 September 2008 pp 355-363 Articles. Purification and molecular cloning of a new galactose-specific lectin from Bauhinia variegata seeds · Luciano S Pinto Celso S Nagano Taianá M Oliveira Tales R ...

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    Home; Journals; Journal of Biosciences. Shweta Dubey. Articles written in Journal of Biosciences. Volume 31 Issue 5 December 2006 pp 497-501. Clipboard: Putting T cells to sleep: a new paradigm for immune evasion by persistent viruses · Shweta Dubey Shahid Jameel · More Details Fulltext PDF ...

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    Home; Journals; Journal of Biosciences. Bhagyashri A Shanbhag. Articles written in Journal of Biosciences. Volume 29 Issue 1 March 2004 pp 105-110 Articles. Factors influencing offspring traits in the oviparous multi-clutched lizard, Calotes versicolor (Agamidae) · Rajkumar S Radder Bhagyashri A Shanbhag.

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    Home; Journals; Journal of Biosciences. Pankaj Kumar. Articles written in Journal of Biosciences. Volume 32 Issue 1 January 2007 pp 3-15 Articles. Simple sequence repeats in mycobacterial genomes · Vattipally B Sreenu Pankaj Kumar Javaregowda Nagaraju Hampapathalu A Nagarajaram · More Details Abstract Fulltext ...

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    Home; Journals; Journal of Biosciences. Rajiv Sarin. Articles written in Journal of Biosciences. Volume 30 Issue 1 February 2005 pp 93-102. Genotype, phenotype and cancer: Role of low penetrance genes and environment in tumour susceptibility · Ashwin Kotnis Rajiv Sarin Rita Mulherkar · More Details Abstract Fulltext ...

  7. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. S A Ranade. Articles written in Journal of Biosciences. Volume 25 Issue 3 September 2000 pp 291-299 Review articles. Role of polyamines and ethylene as modulators of plant senescence · S Pandey S A Ranade P K Nagar Nikhil Kumar · More Details Abstract Fulltext PDF.

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    Home; Journals; Journal of Biosciences. Subrata Basu Ray. Articles written in Journal of Biosciences. Volume 26 Issue 5 December 2001 pp 555-559. Commentary: The enigma of morphine tolerance: recent insights · Subrata Basu Ray Shashi Wadhwa · More Details Fulltext PDF. Volume 29 Issue 1 March 2004 pp 51-56 ...

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  13. Journal of Biosciences | Indian Academy of Sciences

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  14. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. ABDUR RAHAMAN. Articles written in Journal of Biosciences. Volume 42 Issue 2 June 2017 pp 333-344 Review. Regulation of dynamin family proteins by post-translational modifications · USHA P KAR HIMANI DEY ABDUR RAHAMAN · More Details Abstract Fulltext PDF. Dynamin ...

  15. Journal of Biosciences | Indian Academy of Sciences

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  17. Journal of Biosciences | Indian Academy of Sciences

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  18. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Tonina Fernandes. Articles written in Journal of Biosciences. Volume 35 Issue 3 September 2010 pp 427-434 Articles. Unusual radioresistance of nitrogen-fixing cultures of Anabaena strains · Harinder Singh Tonina Fernandes Shree Kumar Apte · More Details Abstract Fulltext PDF.

  19. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. PRATAP C MALI. Articles written in Journal of Biosciences. Volume 43 Issue 1 March 2018 pp 149-154 Mini-Review. Triacylglycerol: nourishing molecule in endurance of Mycobacterium tuberculosis · PRATAP C MALI LAXMAN S MEENA · More Details Abstract Fulltext PDF.

  20. Journal of Biosciences | Indian Academy of Sciences

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  1. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. G P Talwar. Articles written in Journal of Biosciences. Volume 30 Issue 4 September 2005 pp 435-447 Perspectives. A destiny to fulfill · G P Talwar · More Details Fulltext PDF. Volume 34 Issue 6 December 2009 pp 909-916 Articles. A partner monoclonal antibody to Moab 730 kills ...

  4. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Manjula Kalia. Articles written in Journal of Biosciences. Volume 33 Issue 4 November 2008 pp 451-464. Molecular biology and pathogenesis of hepatitis E virus · Vivek Chandra Shikha Taneja Manjula Kalia Shahid Jameel · More Details Abstract Fulltext PDF. The hepatitis E virus ...

  5. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. L Singh. Articles written in Journal of Biosciences. Volume 36 Issue 4 September 2011 pp 739-748 Review. Mango ginger (Curcuma amada Roxb.) – A promising spice for phytochemicals and biological activities · R S Policegoudra S M Aradhya L Singh · More Details Abstract ...

  6. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. D Raghunath. Articles written in Journal of Biosciences. Volume 33 Issue 4 November 2008 pp 593-603. Emerging antibiotic resistance in bacteria with special reference to India · D Raghunath · More Details Abstract Fulltext PDF. The antibiotic era started in the 1940s and changed ...

  7. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Pankaj Verma. Articles written in Journal of Biosciences. Volume 37 Issue 2 June 2012 pp 221-226 Brief communication. Molecular typing of fecal eukaryotic microbiota of human infants and their respective mothers · Prashant K Pandey Jay Siddharth Pankaj Verma Ashish Bavdekar ...

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    Home; Journals; Journal of Biosciences. Vidya Ramachandran. Articles written in Journal of Biosciences. Volume 26 Issue 4 November 2001 pp 437-464. Epidemiological profile of India: Historical and contemporary perspectives · M D Gupte Vidya Ramachandran R K Mutatkar · More Details Abstract Fulltext PDF.

  9. Journal of Biosciences | Indian Academy of Sciences

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  10. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Satish K Amarnath. Articles written in Journal of Biosciences. Volume 33 Issue 4 November 2008 pp 539-547. Brucellosis in India – a review · Basappa G Mantur Satish K Amarnath · More Details Abstract Fulltext PDF. Brucellosis is an important re-emerging zoonosis with a ...

  11. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Xiuhong Yang. Articles written in Journal of Biosciences. Volume 33 Issue 1 March 2008 pp 103-112 Articles. Molecular cloning and characterization of a gene encoding RING zinc finger ankyrin protein from drought-tolerant Artemisia desertorum · Xiuhong Yang Chao Sun Yuanlei ...

  12. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Finny Monickaraj. Articles written in Journal of Biosciences. Volume 38 Issue 1 March 2013 pp 113-122 Articles. Accelerated fat cell aging links oxidative stress and insulin resistance in adipocytes · Finny Monickaraj Sankaramoorthy Aravind Pichamoorthy Nandhini Paramasivam ...

  13. Journal of Biosciences | Indian Academy of Sciences

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  14. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Harinder Singh. Articles written in Journal of Biosciences. Volume 35 Issue 3 September 2010 pp 427-434 Articles. Unusual radioresistance of nitrogen-fixing cultures of Anabaena strains · Harinder Singh Tonina Fernandes Shree Kumar Apte · More Details Abstract Fulltext PDF.

  15. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Jacinta S D'souza. Articles written in Journal of Biosciences. Volume 28 Issue 2 March 2003 pp 223-233 Articles. Purification and characterization of a Ca -dependent/calmodulin-stimulated protein kinase from moss chloronema cells · Jacinta S D'souza Man Mohan Johri.

  16. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Ashwin Kotnis. Articles written in Journal of Biosciences. Volume 30 Issue 1 February 2005 pp 93-102. Genotype, phenotype and cancer: Role of low penetrance genes and environment in tumour susceptibility · Ashwin Kotnis Rajiv Sarin Rita Mulherkar · More Details Abstract Fulltext ...

  17. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. ZAKI ABU RABI. Articles written in Journal of Biosciences. Volume 42 Issue 2 June 2017 pp 265-274 Article. Interleukin 8 in progression of hormone-dependent early breast cancer · JELENA MILOVANOVIĆ NATAŠA TODOROVIĆ-RAKOVIĆ TIJANA VUJASINOVIĆ ZAKI ABU RABI.

  18. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. PAIKE JAYADEVA BHAT. Articles written in Journal of Biosciences. Volume 34 Issue 4 October 2009 pp 513-522 Articles. Epigenetics of the yeast galactose genetic switch · Paike Jayadeva Bhat Revathi S Iyer · More Details Abstract Fulltext PDF. The transcriptional activation of ...

  19. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Subhash C Lakhotia. Articles written in Journal of Biosciences. Volume 29 Issue 3 September 2004 pp 219-224. Commentary: Epigenetics of heterochromatin · Subhash C Lakhotia · More Details Fulltext PDF. Volume 32 Issue 3 April 2007 pp 429-431. Foreword · Subhash C ...

  20. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Michel Morange. Articles written in Journal of Biosciences. Volume 29 Issue 4 December 2004 pp 378-380. Commentary: The death of Francis Crick: the end of a golden age in biology · Michel Morange · More Details Fulltext PDF. Volume 30 Issue 3 June 2005 pp 313-316 Series.

  1. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. MONIDIPA GHOSH. Articles written in Journal of Biosciences. Volume 42 Issue 3 September 2017 pp 427-438 Article. Cholesterol-lowering drug, in combination with chromium chloride, induces early apoptotic signals in intracellular L. donovani amastigotes, leading to death.

  2. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. John Bernet. Articles written in Journal of Biosciences. Volume 28 Issue 3 April 2003 pp 249-264 Articles. Viral mimicry of the complement system · John Bernet Jayati Mullick Akhilesh K Singh Arvind Sahu · More Details Abstract Fulltext PDF. The complement system is a potent ...

  3. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. SADHANA SINGH. Articles written in Journal of Biosciences. Volume 40 Issue 2 June 2015 pp 355-364 Articles. Functional and structural abnormalities associated with empathy in patients with schizophrenia: An fMRI and VBM study · Sadhana Singh Shilpi Modi Satnam Goyal ...

  4. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. MOSAMI GALVANKAR. Articles written in Journal of Biosciences. Volume 42 Issue 2 June 2017 pp 251-263 Article. Estrogen is essential but not sufficient to induce endometriosis · MOSAMI GALVANKAR NEHA SINGH MODI DEEPAK · More Details Abstract Fulltext PDF.

  5. Journal of Biosciences | Indian Academy of Sciences

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  6. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. M Balasubramanyam. Articles written in Journal of Biosciences. Volume 26 Issue 3 September 2001 pp 383-390 Review Article. Orally active insulin mimics: where do we stand now? M Balasubramanyam V Mohan · More Details Abstract Fulltext PDF. The war against diabetes ...

  7. Journal of Biosciences | Indian Academy of Sciences

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  9. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. JIANPING SI. Articles written in Journal of Biosciences. Volume 41 Issue 4 December 2016 pp 727-742 ARTICLE. Functional analyses of Populus euphratica brassinosteroid biosynthesis enzyme genes DWF4 (PeDWF4) and CPD (PeCPD) in the regulation of growth and ...

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    Home; Journals; Journal of Biosciences. LI-MIN FENG. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 547-554 Article. Thymoquinone induces cytotoxicity and reprogramming of EMT in gastric cancer cells by targeting PI3K/Akt/mTOR pathway · LI-MIN FENG XUE-FENG WANG QING-XIAN ...

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    Home; Journals; Journal of Biosciences. P Chauhan. Articles written in Journal of Biosciences. Volume 34 Issue 5 November 2009 pp 729-747 Articles. India at the cross-roads of human evolution · R Patnaik P Chauhan · More Details Abstract Fulltext PDF. The Indian palaeoanthropological record, although patchy at the ...

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    Home; Journals; Journal of Biosciences. Franck Molina. Articles written in Journal of Biosciences. Volume 32 Issue 1 January 2007 pp 145-155 Articles. Formal TCA cycle description based on elementary actions · Pierre Mazière Nicolas Parisey Marie Beurton-Aimar Franck Molina · More Details Abstract Fulltext PDF.

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    Home; Journals; Journal of Biosciences. P Dayanandan. Articles written in Journal of Biosciences. Volume 28 Issue 4 June 2003 pp 455-469 Articles. Structural and histochemical studies on grain-filling in the caryopsis of rice (Oryza sativa L.) S Krishnan P Dayanandan · More Details Abstract Fulltext PDF. The endosperm ...

  18. Journal of Biosciences | Indian Academy of Sciences

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  19. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. QING-XIAN HUANG. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 547-554 Article. Thymoquinone induces cytotoxicity and reprogramming of EMT in gastric cancer cells by targeting PI3K/Akt/mTOR pathway · LI-MIN FENG XUE-FENG WANG ...

  20. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Shobha Rao. Articles written in Journal of Biosciences. Volume 26 Issue 4 November 2001 pp 481-489. Nutritional status of the Indian population · Shobha Rao · More Details Abstract Fulltext PDF. High prevalence of low birth weight, high morbidity and mortality in children and poor ...

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    Home; Journals; Journal of Biosciences. Isaac Salazar-Ciudad. Articles written in Journal of Biosciences. Volume 34 Issue 4 October 2009 pp 573-587 Articles. Looking at the origin of phenotypic variation from pattern formation gene networks · Isaac Salazar-Ciudad · More Details Abstract Fulltext PDF. This article critically ...

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    Home; Journals; Journal of Biosciences. Gregor Durstewitz. Articles written in Journal of Biosciences. Volume 37 Issue 5 November 2012 pp 821-828 Articles. Large SNP arrays for genotyping in crop plants · Martin W Ganal Andreas Polley Eva-Maria Graner Joerg Plieske Ralf Wieseke Hartmut Luerssen Gregor Durstewitz.

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    Home; Journals; Journal of Biosciences. LOCHNER. Articles written in Journal of Biosciences. Volume 43 Issue 1 March 2018 pp 59-74 Article. Thalassiosira mala italic> (Bacillariophyta), a potentially harmful, marine diatom from Chilka Lake and other coastal localities of Odisha, India: Nomenclature, frustule morphology ...

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  12. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Antoinette Molinié. Articles written in Journal of Biosciences. Volume 38 Issue 2 June 2013 pp 189-199. Commentary: On toxic effects of scientific journals · Antoinette Molinié Geoffrey Bodenhausen · More Details Abstract Fulltext PDF. The advent of online publishing greatly ...

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    Home; Journals; Journal of Biosciences. G Keller. Articles written in Journal of Biosciences. Volume 34 Issue 5 November 2009 pp 709-728 Articles. Deccan volcanism, the KT mass extinction and dinosaurs · G Keller A Sahni S Bajpai · More Details Abstract Fulltext PDF. Recent advances in Deccan volcanic studies indicate ...

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    Home; Journals; Journal of Biosciences. Hsinyu Lee. Articles written in Journal of Biosciences. Volume 37 Issue 1 March 2012 pp 157-165 Review. Autophagy: A double-edged sword in Alzheimer's disease · Ying-Tsen Tung Bo-Jeng Wang Ming-Kuan Hu Wen-Ming Hsu Hsinyu Lee Wei-Pang Huang Yung-Feng Liao.

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    Home; Journals; Journal of Biosciences. SUDHANSHU GAUTAM. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 613-621 Article. Small phosphatidate phosphatase ( TtPAH2 ) of Tetrahymena complements respiratory function and not membrane biogenesis function of yeast PAH1.

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  17. Journal of Biosciences | Indian Academy of Sciences

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  18. Journal of Biosciences | Indian Academy of Sciences

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  19. Journal of Biosciences | Indian Academy of Sciences

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  20. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. David L Beveridge. Articles written in Journal of Biosciences. Volume 37 Issue 3 July 2012 pp 379-397 Articles. The ABCs of molecular dynamics simulations on B-DNA, circa 2012 · David L Beveridge Thomas E Cheatham III Mihaly Mezei · More Details Abstract Fulltext PDF.

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    Home; Journals; Journal of Biosciences. PRIYANKA BEDI. Articles written in Journal of Biosciences. Volume 43 Issue 1 March 2018 pp 105-115 Article. Root transcripts associated with arsenic accumulation in hyperaccumulator Pteris vittata · RASIKA M POTDUKHE PRIYANKA BEDI BIJAYA K SARANGI RAM A PANDEY ...

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    Home; Journals; Journal of Biosciences. S A Kulasooriya. Articles written in Journal of Biosciences. Volume 31 Issue 5 December 2006 pp 645-650 Reviews. Interactions among endophytic bacteria and fungi: effects and potentials · W M M S Bandara Gamini Seneviratne S A Kulasooriya · More Details Abstract Fulltext PDF.

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    Home; Journals; Journal of Biosciences. A Adaikala Koteswari. Articles written in Journal of Biosciences. Volume 28 Issue 6 December 2003 pp 715-721 Articles. Curcumin-induced inhibition of cellular reactive oxygen species generation: Novel therapeutic implications · M Balasubramanyam A Adaikala Koteswari R ...

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    Home; Journals; Journal of Biosciences. M T Tanuja. Articles written in Journal of Biosciences. Volume 26 Issue 1 March 2001 pp 71-76 Articles. Incipient sexual isolation in the nasuta-albomicans complex of Drosophila: No-choice experiments · M T Tanuja N B Ramachandra H A Ranganath · More Details Abstract Fulltext ...

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    Home; Journals; Journal of Biosciences. Triptish Bhatia. Articles written in Journal of Biosciences. Volume 27 Issue 1 February 2002 pp 35-52. Molecular genetics of schizophrenia: past, present and future · Suman Prasad Prachi Semwal Smita Deshpande Triptish Bhatia V L Nimgaonkar B K Thelma · More Details Abstract ...

  6. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Amar J S Klar. Articles written in Journal of Biosciences. Volume 35 Issue 1 March 2010 pp 11-15 Perspectives. A proposal for re-defining the way the aetiology of schizophrenia and bipolar human psychiatric diseases is investigated · Amar J S Klar · More Details Abstract Fulltext ...

  7. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. SUMITRA NAIN. Articles written in Journal of Biosciences. Volume 42 Issue 3 September 2017 pp 481-490 Article. Promoter polymorphism MMP-1 (-1607 2G/1G) and MMP-3 (-1612 5A/6A) in development of HAND and modulation of pathogenesis of HAND · HARI OM SINGH ...

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    Home; Journals; Journal of Biosciences. Shree Kumar Apte. Articles written in Journal of Biosciences. Volume 29 Issue 2 June 2004 pp 153-161 Articles. A novel potassium deficiency-induced stimulon in Anabaena torulosa · Anuradha Alahari Shree Kumar Apte · More Details Abstract Fulltext PDF. Potassium deficiency ...

  9. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. JAMUNA R SUBRAMANIAM. Articles written in Journal of Biosciences. Volume 41 Issue 4 December 2016 pp 689-695 ARTICLE. Reserpine requires the D2-type receptor, dop-3 , and the exoribonuclease, eri-1 , to extend the lifespan in C. elegans · KOPAL SAHARIA RANJEET ...

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    Home; Journals; Journal of Biosciences. Mihaly Mezei. Articles written in Journal of Biosciences. Volume 37 Issue 3 July 2012 pp 379-397 Articles. The ABCs of molecular dynamics simulations on B-DNA, circa 2012 · David L Beveridge Thomas E Cheatham III Mihaly Mezei · More Details Abstract Fulltext PDF. This article ...

  12. Journal of Biosciences | Indian Academy of Sciences

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  15. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Ana M soto. Articles written in Journal of Biosciences. Volume 30 Issue 1 February 2005 pp 103-118. Emergentism as a default: Cancer as a problem of tissue organization · Ana M soto Carlos Sonnenschein · More Details Abstract Fulltext PDF. During the last fifty years the dominant ...

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    Home; Journals; Journal of Biosciences. VIDYANAND NANJUNDIAH. Articles written in Journal of Biosciences. Volume 25 Issue 1 March 2000 pp 9-10. Commentary: The smallest form of life yet? Vidyanand Nanjundiah · More Details Fulltext PDF. Volume 28 Issue 6 December 2003 pp 697-707 Articles. Calcium regulates ...

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    Home; Journals; Journal of Biosciences. AMOTZ ZAHAVI. Articles written in Journal of Biosciences. Volume 43 Issue 1 March 2018 pp 49-58 Article. An individual-level selection model for the apparent altruism exhibited by cellular slime moulds · AMOTZ ZAHAVI KEITH D HARRIS VIDYANAND NANJUNDIAH · More Details ...

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    Home; Journals; Journal of Biosciences. Carlos Sonnenschein. Articles written in Journal of Biosciences. Volume 30 Issue 1 February 2005 pp 103-118. Emergentism as a default: Cancer as a problem of tissue organization · Ana M soto Carlos Sonnenschein · More Details Abstract Fulltext PDF. During the last fifty years the ...

  20. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Marta Linde-Medina. Articles written in Journal of Biosciences. Volume 36 Issue 4 September 2011 pp 575-585 Brief communication. Adaptation or exaptation? The case of the human hand · Marta Linde-Medina · More Details Abstract Fulltext PDF. A controversy of relevance to the ...

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    Home; Journals; Journal of Biosciences. Sangappa. Articles written in Journal of Biosciences. Volume 30 Issue 2 March 2005 pp 259-268 Articles. Crystal structure of raw pure Mysore silk fibre based on (Ala-Gly)2-Ser-Gly peptide sequence using Linked-Atom-Least-Squares method · Sangappa S S Mahesh R Somashekar.

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    Home; Journals; Journal of Biosciences. JASWANDI UJWAL DANDEKAR. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 585-601 Article. Fermentative metabolism impedes p53-dependent apoptosis in a Crabtree-positive but not in Crabtree-negative yeast · ABHAY KUMAR JASWANDI ...

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    Home; Journals; Journal of Biosciences. Anurag Kumar Mishra. Articles written in Journal of Biosciences. Volume 27 Issue 3 June 2002 pp 251-259 Articles. Cloning and sequencing of complete -crystallin cDNA from embryonic lens of Crocodylus palustris · Raman Agrawal Reena Chandrashekhar Anurag Kumar Mishra ...

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    Home; Journals; Journal of Biosciences. Indranil Dasgupta. Articles written in Journal of Biosciences. Volume 37 Issue 4 September 2012 pp 791-806 Review. Begomovirus research in India: A critical appraisal and the way ahead · Basanta K Borah Indranil Dasgupta · More Details Abstract Fulltext PDF. Begomoviruses are ...

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    Home; Journals; Journal of Biosciences. R S Sharma. Articles written in Journal of Biosciences. Volume 26 Issue 4 November 2001 pp 391-405. Current status of fertility control methods in India · R S Sharma M Rajalakshmi D Antony Jeyaraj · More Details Abstract Fulltext PDF. Approximately 48.2% of couples of 15 to 49 ...

  11. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. SHUGUANG HAN. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 671-681 Article. MiR-876-5p suppresses epithelial-mesenchymal transition of lung cancer by directly down-regulating bone morphogenetic protein 4 · LIANG BAO LEI LV JINPING ...

  12. Journal of Biosciences | Indian Academy of Sciences

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  13. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Scott F Gilbert. Articles written in Journal of Biosciences. Volume 26 Issue 3 September 2001 pp 293-298. Commentary: New vistas for developmental biology · Scott F Gilbert Rocky S Tuan · More Details Fulltext PDF. Volume 27 Issue 5 September 2002 pp 445-446. Commentary: ...

  14. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Partha P Majumder. Articles written in Journal of Biosciences. Volume 26 Issue 4 November 2001 pp 390a-390a. Preface · Partha P Majumder A Jagannadha Rao · More Details Fulltext PDF. Volume 26 Issue 4 November 2001 pp 533-545. Ethnic populations of India as seen from ...

  15. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. XINHUA WANG. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 671-681 Article. MiR-876-5p suppresses epithelial-mesenchymal transition of lung cancer by directly down-regulating bone morphogenetic protein 4 · LIANG BAO LEI LV JINPING ...

  16. Journal of Biosciences | Indian Academy of Sciences

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    Home; Journals; Journal of Biosciences. Q M I Haq. Articles written in Journal of Biosciences. Volume 36 Issue 2 June 2011 pp 329-340 Articles. Mutagenesis in ORF AV2 affects viral replication in Mungbean yellow mosaic India virus · A Rouhibakhsh Q M I Haq V G Malathi · More Details Abstract Fulltext PDF. Mungbean ...

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    Home; Journals; Journal of Biosciences. Girish J Kotwal. Articles written in Journal of Biosciences. Volume 28 Issue 3 April 2003 pp 265-271 Articles. Vaccinia complement control protein: Multi-functional protein and a potential wonder drug · Purushottam Jha Girish J Kotwal · More Details Abstract Fulltext PDF. Vaccinia ...

  4. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Saqib Mahmood. Articles written in Journal of Biosciences. Volume 40 Issue 3 September 2015 pp 521-530 Articles. Role of leptin G-2548A polymorphism in age- and gender-specific development of obesity · Adeela Shahid Sobia Rana Saqib Mahmood Shahid Saeed · More Details ...

  5. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. SHUKLA SUSHMITA. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 613-621 Article. Small phosphatidate phosphatase ( TtPAH2 ) of Tetrahymena complements respiratory function and not membrane biogenesis function of yeast PAH1.

  6. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Sinha Sinha. Articles written in Journal of Biosciences. Volume 39 Issue 3 June 2014 pp 525-536 Reviews. Conservation of PHO pathway in ascomycetes and the role of Pho84 · Parul Tomar Sinha Sinha · More Details Abstract Fulltext PDF. In budding yeast, Saccharomyces ...

  7. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. ANANT B PATEL. Articles written in Journal of Biosciences. Volume 42 Issue 3 September 2017 pp 363-371 Brief communication. Amalaki Rasayana improved memory and neuronal metabolic activity in AβPP-PS1 mouse model of Alzheimer's disease · VIVEK TIWARI KAMAL SABA ...

  8. East Midlands healthcare and bioscience sector strategy

    OpenAIRE

    East Midlands Development Agency

    2007-01-01

    The healthcare and bioscience sector is one of four priority sectors identified in the regional economic strategy, A Flourishing Region. This document sets out a strategy for maximising the contribution of the healthcare and biosciences sector to the economic development of the East Midlands.

  9. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. T Naga Sowjanya. Articles written in Journal of Biosciences. Volume 35 Issue 4 December 2010 pp 539-546 Articles. Translocations used to generate chromosome segment duplications in Neurospora can disrupt genes and create novel open reading frames · Parmit K Singh ...

  10. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. NILOFER NAQVI. Articles written in Journal of Biosciences. Volume 43 Issue 1 March 2018 pp 127-138 Article. Blocking dephosphorylation at Serine 120 residue in t-SNARE SNAP-23 leads to massive inhibition in exocytosis from mast cells · NASKAR PIEU NILOFER NAQVI NITI ...

  11. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. SHRUTI D MARATHE. Articles written in Journal of Biosciences. Volume 42 Issue 3 September 2017 pp 481-490 Article. Promoter polymorphism MMP-1 (-1607 2G/1G) and MMP-3 (-1612 5A/6A) in development of HAND and modulation of pathogenesis of HAND · HARI OM SINGH ...

  12. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. JASMINE M SHAH. Articles written in Journal of Biosciences. Volume 43 Issue 1 March 2018 pp 173-187 Review. Plant reference genes for development and stress response studies · JOYOUS T JOSEPH NAJYA JABEEN POOLAKKALODY JASMINE M SHAH · More Details Abstract ...

  13. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Pushpa Mittra Bhargava. Articles written in Journal of Biosciences. Volume 34 Issue 2 June 2009 pp 167-168. Commentary: Insufficient regulatory supervision prior to release of genetically modified crops for commercial cultivation in India · Pushpa Mittra Bhargava · More Details ...

  14. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. PRABHJOT KAUR. Articles written in Journal of Biosciences. Volume 40 Issue 2 June 2015 pp 355-364 Articles. Functional and structural abnormalities associated with empathy in patients with schizophrenia: An fMRI and VBM study · Sadhana Singh Shilpi Modi Satnam Goyal ...

  15. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Madhuri Thakar. Articles written in Journal of Biosciences. Volume 33 Issue 4 November 2008 pp 515-525. HIV infection in India: Epidemiology, molecular epidemiology and pathogenesis. Samir Lakhashe Madhuri Thakar Sheela Godbole Srikanth Tripathy Ramesh Paranjape.

  16. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. JAMES A NIENOW. Articles written in Journal of Biosciences. Volume 43 Issue 1 March 2018 pp 59-74 Article. Thalassiosira mala italic> (Bacillariophyta), a potentially harmful, marine diatom from Chilka Lake and other coastal localities of Odisha, India: Nomenclature, frustule ...

  17. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. D BANSAL. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 531-535 Brief communication. Antifolate drug resistance: Novel mutations and haplotype distribution in dhps and dhfr from Northeast India · NP SARMAH K SARMA DR BHATTACHARYYA ...

  18. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. SHEETAL S NARVEKAR. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 647-656 Article. IGF1 stimulates differentiation of primary follicles and their growth in ovarian explants of zebrafish ( Danio rerio ) cultured in vitro · PANCHARATNA A KATTI ...

  19. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Antonio G Valdecasas. Articles written in Journal of Biosciences. Volume 34 Issue 6 December 2009 pp 835-843 Perspectives. Understanding complex systems: lessons from Auzoux's and von Hagens's anatomical models · Antonio G Valdecasas Ana M Correas Carmen R Guerrero ...

  20. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. B N Singh. Articles written in Journal of Biosciences. Volume 34 Issue 2 June 2009 pp 263-274 Articles. Variations in morphological and life-history traits under extreme temperatures in Drosophila ananassae · Seema Sisodia B N Singh · More Details Abstract Fulltext PDF.

  1. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Rahul Gaur. Articles written in Journal of Biosciences. Volume 32 Issue 4 June 2007 pp 747-754 Articles. Diet-dependent depletion of queuosine in tRNAs in Caenorhabditis elegans does not lead to a developmental block · Rahul Gaur Glenn R Björk Simon Tuck Umesh Varshney.

  2. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Smita Deshpande. Articles written in Journal of Biosciences. Volume 27 Issue 1 February 2002 pp 35-52. Molecular genetics of schizophrenia: past, present and future · Suman Prasad Prachi Semwal Smita Deshpande Triptish Bhatia V L Nimgaonkar B K Thelma · More Details ...

  3. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. S Ignacimuthu. Articles written in Journal of Biosciences. Volume 31 Issue 3 September 2006 pp 339-345 Articles. Agrobacterium-mediated transformation of chickpea with -amylase inhibitor gene for insect resistance · S Ignacimuthu S Prakash · More Details Abstract Fulltext PDF.

  4. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Vindhya Mohindra. Articles written in Journal of Biosciences. Volume 38 Issue 2 June 2013 pp 373-383 Articles. Physiological responses to acute experimental hypoxia in the air-breathing Indian catfish, Clarias batrachus (Linnaeus, 1758) · Ratnesh Kumar Tripathi Vindhya Mohindra ...

  5. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Will D Penny. Articles written in Journal of Biosciences. Volume 32 Issue 1 January 2007 pp 129-144 Articles. Dynamic causal models of neural system dynamics: current state and future extensions · Klaas E Stephan Lee M Harrison Stefan J Kiebel Olivier David Will D Penny Karl J ...

  6. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. STHITAPRANJYA PATI. Articles written in Journal of Biosciences. Volume 43 Issue 1 March 2018 pp 85-95 Article. Acute pharmacogenetic activation of medial prefrontal cortex excitatory neurons regulates anxiety-like behaviour · STHITAPRANJYA PATI ANKIT SOOD SOURISH ...

  7. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Shikha Srivastava. Articles written in Journal of Biosciences. Volume 37 Issue 1 March 2012 pp 63-72 Articles. High prevalence of oncogenic HPV-16 in cervical smears of asymptomatic women of eastern Uttar Pradesh, India: A population-based study · Shikha Srivastava Sadhana ...

  8. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Rajkumar S. Articles written in Journal of Biosciences. Volume 29 Issue 1 March 2004 pp 105-110 Articles. Factors influencing offspring traits in the oviparous multi-clutched lizard, Calotes versicolor (Agamidae) · Rajkumar S Radder Bhagyashri A Shanbhag · More Details Abstract ...

  9. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Gavan Holloway. Articles written in Journal of Biosciences. Volume 28 Issue 3 April 2003 pp 323-335 Articles. HIV-1 Nef control of cell signalling molecules: multiple strategies to promote virus replication · Alison L Greenway Gavan Holloway Dale A McPhee Phoebe Ellis Alyssa ...

  10. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. K B Saxena. Articles written in Journal of Biosciences. Volume 37 Issue 5 November 2012 pp 811-820 Articles. Advances in genetics and molecular breeding of three legume crops of semi-arid tropics using next-generation sequencing and high-throughput genotyping technologies.

  11. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Vibha Tandon. Articles written in Journal of Biosciences. Volume 37 Issue 3 July 2012 pp 493-502 Articles. Inhibition of HIV-1 Integrase gene expression by 10-23 DNAzyme · Nirpendra Singh Atul Ranjan Souvik Sur Ramesh Chandra Vibha Tandon · More Details Abstract Fulltext ...

  12. Comparison of Four Search Engines and their efficacy With Emphasis on Literature Research in Addiction (Prevention and Treatment).

    Science.gov (United States)

    Samadzadeh, Gholam Reza; Rigi, Tahereh; Ganjali, Ali Reza

    2013-01-01

    Surveying valuable and most recent information from internet, has become vital for researchers and scholars, because every day, thousands and perhaps millions of scientific works are brought out as digital resources which represented by internet and researchers can't ignore this great resource to find related documents for their literature search, which may not be found in any library. With regard to variety of documents presented on the internet, search engines are one of the most effective search tools for finding information. The aim of this study is to evaluate the three criteria, recall, preciseness and importance of the four search engines which are PubMed, Science Direct, Google Scholar and federated search of Iranian National Medical Digital Library in addiction (prevention and treatment) to select the most effective search engine for offering the best literature research. This research was a cross-sectional study by which four popular search engines in medical sciences were evaluated. To select keywords, medical subject heading (Mesh) was used. We entered given keywords in the search engines and after searching, 10 first entries were evaluated. Direct observation was used as a mean for data collection and they were analyzed by descriptive statistics (number, percent number and mean) and inferential statistics, One way analysis of variance (ANOVA) and post hoc Tukey in Spss. 15 statistical software. P Value search engines had different operations with regard to the evaluated criteria. Since P Value was 0.004 search engines. PubMed, Science Direct and Google Scholar were the best in recall, preciseness and importance respectively. As literature research is one of the most important stages of research, it's better for researchers, especially Substance-Related Disorders scholars to use different search engines with the best recall, preciseness and importance in that subject field to reach desirable results while searching and they don't depend on just one

  13. Impact of librarians on reporting of the literature searching component of pediatric systematic reviews*

    Science.gov (United States)

    Meert, Deborah; Torabi, Nazi; Costella, John

    2016-01-01

    Objective A critical element in conducting a systematic review is the identification of studies. To date, very little empirical evidence has been reported on whether the presence of a librarian or information professional can contribute to the quality of the final product. The goal of this study was to compare the reporting rigor of the literature searching component of systematic reviews with and without the help of a librarian. Method Systematic reviews published from 2002 to 2011 in the twenty highest impact factor pediatrics journals were collected from MEDLINE. Corresponding authors were contacted via an email survey to determine if a librarian was involved, the role that the librarian played, and functions that the librarian performed. The reviews were scored independently by two reviewers using a fifteen-item checklist. Results There were 186 reviews that met the inclusion criteria, and 44% of the authors indicated the involvement of a librarian in conducting the systematic review. With the presence of a librarian as coauthor or team member, the mean checklist score was 8.40, compared to 6.61 (plibrarian. Conclusions Findings indicate that having a librarian as a coauthor or team member correlates with a higher score in the literature searching component of systematic reviews. PMID:27822147

  14. A literature search tool for intelligent extraction of disease-associated genes.

    Science.gov (United States)

    Jung, Jae-Yoon; DeLuca, Todd F; Nelson, Tristan H; Wall, Dennis P

    2014-01-01

    To extract disorder-associated genes from the scientific literature in PubMed with greater sensitivity for literature-based support than existing methods. We developed a PubMed query to retrieve disorder-related, original research articles. Then we applied a rule-based text-mining algorithm with keyword matching to extract target disorders, genes with significant results, and the type of study described by the article. We compared our resulting candidate disorder genes and supporting references with existing databases. We demonstrated that our candidate gene set covers nearly all genes in manually curated databases, and that the references supporting the disorder-gene link are more extensive and accurate than other general purpose gene-to-disorder association databases. We implemented a novel publication search tool to find target articles, specifically focused on links between disorders and genotypes. Through comparison against gold-standard manually updated gene-disorder databases and comparison with automated databases of similar functionality we show that our tool can search through the entirety of PubMed to extract the main gene findings for human diseases rapidly and accurately.

  15. LITERATURE SEARCH FOR METHODS FOR HAZARD ANALYSES OF AIR CARRIER OPERATIONS.

    Energy Technology Data Exchange (ETDEWEB)

    MARTINEZ - GURIDI,G.; SAMANTA,P.

    2002-07-01

    Representatives of the Federal Aviation Administration (FAA) and several air carriers under Title 14 of the Code of Federal Regulations (CFR) Part 121 developed a system-engineering model of the functions of air-carrier operations. Their analyses form the foundation or basic architecture upon which other task areas are based: hazard analyses, performance measures, and risk indicator design. To carry out these other tasks, models may need to be developed using the basic architecture of the Air Carrier Operations System Model (ACOSM). Since ACOSM encompasses various areas of air-carrier operations and can be used to address different task areas with differing but interrelated objectives, the modeling needs are broad. A literature search was conducted to identify and analyze the existing models that may be applicable for pursuing the task areas in ACOSM. The intent of the literature search was not necessarily to identify a specific model that can be directly used, but rather to identify relevant ones that have similarities with the processes and activities defined within ACOSM. Such models may provide useful inputs and insights in structuring ACOSM models. ACOSM simulates processes and activities in air-carrier operation, but, in a general framework, it has similarities with other industries where attention also has been paid to hazard analyses, emphasizing risk management, and in designing risk indicators. To assure that efforts in other industries are adequately considered, the literature search includes publications from other industries, e.g., chemical, nuclear, and process industries. This report discusses the literature search, the relevant methods identified and provides a preliminary assessment of their use in developing the models needed for the ACOSM task areas. A detailed assessment of the models has not been made. Defining those applicable for ACOSM will need further analyses of both the models and tools identified. The report is organized in four chapters

  16. Literature search, review, and compilation of data for chemical and radiochemical sensors: Task 1 report

    International Nuclear Information System (INIS)

    1993-01-01

    During the next several decades, the US Department of Energy is expected to spend tens of billions of dollars in the characterization, cleanup, and monitoring of DOE's current and former installations that have various degrees of soil and groundwater contamination made up of both hazardous and mixed wastes. Each of these phases will require site surveys to determine type and quantity of hazardous and mixed wastes. It is generally recognized that these required survey and monitoring efforts cannot be performed using traditional chemistry methods based on laboratory evaluation of samples from the field. For that reason, a tremendous push during the past decade or so has been made on research and development of sensors. This report contains the results of an extensive literature search on sensors that are used or have applicability in environmental and waste management. While restricting the search to a relatively small part of the total chemistry spectrum, a sizable body of reference material is included. Results are presented in tabular form for general references obtained from data base searches, as narrative reviews of relevant chapters from proceedings, as book reviews, and as reviews of journal articles with particular relevance to the review. Four broad sensor types are covered: electrochemical processes, piezoelectric devices, fiber optics, and radiochemical processes. The topics of surface chemistry processes and biosensors are not treated separately because they often are an adjunct to one of the four sensors listed. About 1,000 tabular entries are listed, including selected journal articles, reviews of conference/meeting proceedings, and books. Literature to about mid-1992 is covered

  17. Literature search, review, and compilation of data for chemical and radiochemical sensors: Task 1 report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1993-01-01

    During the next several decades, the US Department of Energy is expected to spend tens of billions of dollars in the characterization, cleanup, and monitoring of DOE`s current and former installations that have various degrees of soil and groundwater contamination made up of both hazardous and mixed wastes. Each of these phases will require site surveys to determine type and quantity of hazardous and mixed wastes. It is generally recognized that these required survey and monitoring efforts cannot be performed using traditional chemistry methods based on laboratory evaluation of samples from the field. For that reason, a tremendous push during the past decade or so has been made on research and development of sensors. This report contains the results of an extensive literature search on sensors that are used or have applicability in environmental and waste management. While restricting the search to a relatively small part of the total chemistry spectrum, a sizable body of reference material is included. Results are presented in tabular form for general references obtained from data base searches, as narrative reviews of relevant chapters from proceedings, as book reviews, and as reviews of journal articles with particular relevance to the review. Four broad sensor types are covered: electrochemical processes, piezoelectric devices, fiber optics, and radiochemical processes. The topics of surface chemistry processes and biosensors are not treated separately because they often are an adjunct to one of the four sensors listed. About 1,000 tabular entries are listed, including selected journal articles, reviews of conference/meeting proceedings, and books. Literature to about mid-1992 is covered.

  18. Development of a PubMed Based Search Tool for Identifying Sex and Gender Specific Health Literature.

    Science.gov (United States)

    Song, Michael M; Simonsen, Cheryl K; Wilson, Joanna D; Jenkins, Marjorie R

    2016-02-01

    An effective literature search strategy is critical to achieving the aims of Sex and Gender Specific Health (SGSH): to understand sex and gender differences through research and to effectively incorporate the new knowledge into the clinical decision making process to benefit both male and female patients. The goal of this project was to develop and validate an SGSH literature search tool that is readily and freely available to clinical researchers and practitioners. PubMed, a freely available search engine for the Medline database, was selected as the platform to build the SGSH literature search tool. Combinations of Medical Subject Heading terms, text words, and title words were evaluated for optimal specificity and sensitivity. The search tool was then validated against reference bases compiled for two disease states, diabetes and stroke. Key sex and gender terms and limits were bundled to create a search tool to facilitate PubMed SGSH literature searches. During validation, the search tool retrieved 50 of 94 (53.2%) stroke and 62 of 95 (65.3%) diabetes reference articles selected for validation. A general keyword search of stroke or diabetes combined with sex difference retrieved 33 of 94 (35.1%) stroke and 22 of 95 (23.2%) diabetes reference base articles, with lower sensitivity and specificity for SGSH content. The Texas Tech University Health Sciences Center SGSH PubMed Search Tool provides higher sensitivity and specificity to sex and gender specific health literature. The tool will facilitate research, clinical decision-making, and guideline development relevant to SGSH.

  19. An overview of biomedical literature search on the World Wide Web in the third millennium.

    Science.gov (United States)

    Kumar, Prince; Goel, Roshni; Jain, Chandni; Kumar, Ashish; Parashar, Abhishek; Gond, Ajay Ratan

    2012-06-01

    Complete access to the existing pool of biomedical literature and the ability to "hit" upon the exact information of the relevant specialty are becoming essential elements of academic and clinical expertise. With the rapid expansion of the literature database, it is almost impossible to keep up to date with every innovation. Using the Internet, however, most people can freely access this literature at any time, from almost anywhere. This paper highlights the use of the Internet in obtaining valuable biomedical research information, which is mostly available from journals, databases, textbooks and e-journals in the form of web pages, text materials, images, and so on. The authors present an overview of web-based resources for biomedical researchers, providing information about Internet search engines (e.g., Google), web-based bibliographic databases (e.g., PubMed, IndMed) and how to use them, and other online biomedical resources that can assist clinicians in reaching well-informed clinical decisions.

  20. Place Attachment, Place Identity and the Development of the Child's Self-Identity: Searching the Literature to Develop an Hypothesis

    Science.gov (United States)

    Spencer, Christopher

    2005-01-01

    This is part of a campaign to encourage educational researchers, geographers in particular, to spread their literature searches beyond their immediate subject area. The question of place attachment and identity is reviewed through the psychologistal literature. The hypothesis is offered and supported, that place, in a geographical sense is also…

  1. Evaluation of hospital staff’s perceived quality of librarian-mediated literature searching services*,†

    Science.gov (United States)

    McKeown, Sandra; Konrad, Shauna-Lee; McTavish, Jill; Boyce, Erin

    2017-01-01

    Objective The research evaluated the perceived quality of librarian-mediated literature searching services at one of Canada’s largest acute care teaching hospitals for the purpose of continuous quality improvement and investigation of relationships between variables that can impact user satisfaction. Methods An online survey was constructed using evidence-based methodologies. A systematic sample of staff and physicians requesting literature searches at London Health Sciences Centre were invited to participate in the study over a one-year period. Data analyses included descriptive statistics of closed-ended questions and coding of open-ended questions. Results A range of staff including clinicians, researchers, educators, leaders, and analysts submitted a total of 137 surveys, representing a response rate of 71%. Staff requested literature searches for the following “primary” purposes: research or publication (34%), teaching or training (20%), informing a policy or standard practice (16%), patient care (15%), and “other” purposes (15%). While the majority of staff (76%) submitted search requests using methods of written communication, including email and search request forms, staff using methods of verbal communication, including face-to-face and telephone conversations, were significantly more likely to be extremely satisfied with the librarian’s interpretation of the search request (p=0.004) and to rate the perceived quality of the search results as excellent (p=0.005). In most cases, librarians followed up with staff to clarify the details of their search requests (72%), and these staff were significantly more likely to be extremely satisfied with the librarian’s interpretation of the search request (p=0.002). Conclusions Our results demonstrate the limitations of written communication in the context of librarian-mediated literature searching and suggest a multifaceted approach to quality improvement efforts. PMID:28377674

  2. Delivering a MOOC for literature searching in health libraries: evaluation of a pilot project.

    Science.gov (United States)

    Young, Gil; McLaren, Lisa; Maden, Michelle

    2017-12-01

    In an era when library budgets are being reduced, Massive Online Open Courses (MOOC's) can offer practical and viable alternatives to the delivery of costly face-to-face training courses. In this study, guest writers Gil Young from Health Care Libraries Unit - North, Lisa McLaren from Brighton and Sussex Medical School and Liverpool University PhD student Michelle Maden describe the outcomes of a funded project they led to develop a MOOC to deliver literature search training for health librarians. Funded by Health Education England, the MOOC was developed by the Library and Information Health Network North West as a pilot project that ran for six weeks. In particular, the MOOC target audience is discussed, how content was developed for the MOOC, promotion and participation, cost-effectiveness, evaluation, the impact of the MOOC and recommendations for future development. H. S. © 2017 Health Libraries Group.

  3. Conducting systematic reviews of intervention questions I: Writing the review protocol, formulating the question and searching the literature.

    Science.gov (United States)

    O'Connor, A M; Anderson, K M; Goodell, C K; Sargeant, J M

    2014-06-01

    This article is the fourth of six articles addressing systematic reviews in animal agriculture and veterinary medicine. Previous articles in the series have introduced systematic reviews, discussed study designs and hierarchies of evidence, and provided details on conducting randomized controlled trials, a common design for use in systematic reviews. This article describes development of a review protocol and the first two steps in a systematic review: formulating a review question, and searching the literature for relevant research. The emphasis is on systematic reviews of questions related to interventions. The review protocol is developed prior to conducting the review and specifies the plan for the conduct of the review, identifies the roles and responsibilities of the review team and provides structured definitions related to the review question. For intervention questions, the review question should be defined by the PICO components: population, intervention, comparison and outcome(s). The literature search is designed to identify all potentially relevant original research that may address the question. Search terms related to some or all of the PICO components are entered into literature databases, and searches for unpublished literature also are conducted. All steps of the literature search are documented to provide transparent reporting of the process. © 2014 Blackwell Verlag GmbH.

  4. What is provided and what the registered nurse needs--bioscience learning through the pre-registration curriculum.

    Science.gov (United States)

    Davis, Geraldine M

    2010-11-01

    Registered nurses undertaking programmes of study to become non-medical prescribers appear to have limited biological science knowledge. A case study was undertaken to determine whether the nurses entering Prescriber programmes considered studies in bioscience in their pre-registration nursing courses had been sufficient, linked to practice, and had prepared them for their roles as registered nurses. The literature identifies a continuing trend amongst nursing students describing a lack of sufficient bioscience in initial nurse education; there is limited literature on the views of experienced registered nurses. The participants in this study were 42 registered nurses from adult and mental health nursing, community and inpatient services. The results obtained from questionnaires and interviews are described. Questionnaire analysis identified that 57.1% of participants indicated bioscience in their pre-registration nursing programme had been limited and 40.5% stated the bioscience content had not prepared them for their roles on registration. Those reporting extensive coverage of bioscience were all aged over 41 years and had qualified before 1995. Greatest coverage of bioscience in pre-registration programmes was reported in relation to anatomy and physiology, with relatively limited coverage of microbiology, pharmacology or biochemistry. Respondents considered all five topics to be important. Interviews supported the questionnaire findings. Copyright © 2010 Elsevier Ltd. All rights reserved.

  5. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 36; Issue 5 ... Department of Physiology, Kangwon National University School of Medicine, Chuncheon ... Faculty of Applied Marine Science, Cheju National University, Jeju 690-756, Republic ...

  6. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 34; Issue 1 ... an overview of the implications of such a phenomenon for basic and applied research. ... Department of Crop Biology, Section of Plant Physiology, University of Pisa, Pisa, Italy ...

  7. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 38; Issue 4 ... Department of Plant Physiology, UPSC, Umeå University, S-90187 Umea, Sweden; Ecologie ... Lyon, France; Faculty of Applied Sciences, Department of Botany, University of Sri ...

  8. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 28; Issue 4 ... of stochastic differential equation; spectral density; Tchebycheff's inequality ... Estimation of maximum harvesting effort has a great impact on the economics of fisheries and other ...

  9. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    A model for cell type localization in the migrating slug of Dictyostelium discoideum based on differential ... a progressive maturation of chemotactic properties during the transdifferentiation of slug cell types. ... Journal of Biosciences | News ...

  10. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 36; Issue 2 ... The nucleus accumbens (NAc), a critical structure of the brain reward circuit, is implicated in ... Reduction in the conductance of KIR channels evokes facilitatory effects on EPSPs ...

  11. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 30; Issue 2 ... From about 6000 brain sub-oesophageal ganglion complexes, the neuropeptide was isolated; and purified ... Radiochemical bioassay confirmed the pheromonotropic effect of the ...

  12. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 33; Issue 1. A songbird forebrain area potentially involved in auditory discrimination and memory formation ... a set of interconnected ascending and descending auditory brain pathways that ...

  13. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Effect of chronic exposure to aspartame on oxidative stress in the brain of albino rats ... whether chronic aspartame (75 mg/kg) administration could release methanol and induce oxidative stress in the rat brain. ... Journal of Biosciences | News ...

  14. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Apoptosis; bee; brain; cell division; nervous system ... have a distinct morphology, physiology and behaviour that correlate with their roles in the society and are characterized by some brain polymorphisms. ... Journal of Biosciences | News ...

  15. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Zinc finger protein 521 is highly expressed in brain, neural stem cells and early ... Fndc5, a precursor of Irisin has inducing effects on the expression level of brain derived neurotrophic factor in hippocampus. ... Journal of Biosciences | News ...

  16. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Brain; differential proteomics; ICAT; LCM; neuron; tandem mass spectrometry ... but also for gaining valuable understanding into brain function and deciphering proteomics from the workbench to the bedside. ... Journal of Biosciences | News ...

  17. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Role of sound stimulation in reprogramming brain connectivity. Sraboni Chaudhury Tapas C Nag Suman Jain Shashi Wadhwa ... Keywords. Auditory pathway; avian; brain; sound stimulation; synaptic plasticity ... Journal of Biosciences | News ...

  18. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Amelioration of altered antioxidant status and membrane linked functions by vanadium and Trigonella in alloxan diabetic rat brains ... determined in different fractions of whole brain after 21 days of treatment. ... Journal of Biosciences | News ...

  19. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    HPLC analysis reveals the presence of beta amyloid in the OVX and HCL mice brain. Congo red staining analysis revealed the extent of amyloid deposition in OVX and hypercholesterolemia mice brain. ... Journal of Biosciences | News ...

  20. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Brain-derived neurotrophic factor and early-life stress: Multifaceted interplay. NATALYA P ... Abstract. The brain-derived neurotrophic factor (BDNF) is a key regulator of neural development and plasticity. ... Journal of Biosciences | News ...

  1. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    In the same brain areas, VBM results also showed reduced grey and white matter volumes. ... alterations and disturbed functional brain activation during empathy task in persons affected with schizophrenia. ... Journal of Biosciences | News ...

  2. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Insights into brain development and disease from neurogenetic analyses in Drosophila melanogaster ... operate in neural stem cells during normal brain development and during abnormal brain tumorigenesis. ... Journal of Biosciences | News ...

  3. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Information for Authors ... Submission of a manuscript will be held to imply that the work reported in it is original, that .... when essential should be numbered consecutively and typed on a separate sheet.

  4. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 40; Issue 4 ... the clusters obtained by a clustering algorithm applied on cancer gene expression data. ... In this context, we have used biochemical pathways, -value statistics of GO attributes, ...

  5. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 30; Issue 5 ... A genomic library was generated using HindIII and the positive clones were sequenced and ... People's Republic of China; School of Agricultural Science and Technology, Suzhou ...

  6. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 34; Issue 2 ... (peptides A, B, C, and D) were selected using a phage display 12-mer peptide library. ... School of Medicine and Pharmaceutics, Jiangnan University, Wuxi, Jiangsu 214122, ...

  7. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 29; Issue 4 ... Plant Biotechnology Research Center, School of Agriculture and Biology, ... D Center, School of Life Sciences, Morgan-Tan International Center for Life Sciences, Fudan University ...

  8. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 32; Issue 2 ... School of Life Sciences, Morgan-Tan International Center for Life Sciences, Fudan University, ... of China; Plant Biotechnology Research Center, School of Agriculture and Biology, ...

  9. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 33; Issue 2 ... R & D Center, Morgan-Tan International Center for Life Sciences, Fudan University, ... School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China ...

  10. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 31; Issue 1 ... and Plant Breeding, University of Agricultural Sciences, Bangalore 560 065, India; Biometrics and Bioinformatics Unit, International Rice Research Institute, Los Banos, Philippines ...

  11. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 39; Issue 3 ... International Crops Research Institute for the Semi-Arid Tropics (ICRISAT), Patancheru 502 ... Punjab Agricultural University, Ludhiana 141 027, India; RAK College of Agriculture, ...

  12. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 31; Issue 2 ... School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200030, ... D Center, Morgan-Tan International Center for Life Sciences, Fudan University, Shanghai ...

  13. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 36; Issue 2 ... Department of Horticulture, Agriculture Faculty, Ilam University, Ilam, Iran; Plant Molecular Biology Group, International Centre for Genetic Engineering and Biotechnology, New ...

  14. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2009-10-26

    Oct 26, 2009 ... Home; Journals; Journal of Biosciences; Volume 34; Issue 5 ... the Early Pleistocene of East Africa, Western Asia and Southeast Asia, thus indirectly ... Centre of Advanced Studies in Geology, Panjab University, Chandigarh ...

  15. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2007-06-28

    Jun 28, 2007 ... Home; Journals; Journal of Biosciences; Volume 32; Issue 5 ... These methods suffer from disadvantages such as the lack of availability of ... In this work, we have constructed a library of local conformation classes purely ...

  16. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 35; Issue 1 ... profiling combined with physiological analysis at two time points for soybean seedlings in ... waterlogging through the management of carbohydrate consumption and by regulating ...

  17. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2011-08-07

    Aug 7, 2011 ... Home; Journals; Journal of Biosciences; Volume 36; Issue 3 ... pathways in animal models of human disease and in patients to provide insights ... progression of metastasis, immune cell trafficking, stem cell therapy, transgenic ...

  18. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2009-08-10

    Aug 10, 2009 ... A ubiquitous cue eliciting these plastic phenotypic responses is ... Among the conclusions that emerge from this exploration is the perspective that the plant cell is phenotypically plastic. ... Journal of Biosciences | News ...

  19. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 41; Issue 3 ... Asthma is a chronic disease due to inflammation of the airways of lungs that is clinically ... ACE insertion/deletion (I/D) polymorphism, rs4646994, in asthma in Pakistani patients.

  20. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 40; Issue 2 ... whole animal was studied after adaptation to low and high concentrations of riboflavin. ... India; Department of Molecular Microbiology, School of Biotechnology, Madurai Kamaraj ...

  1. [How do authors of systematic reviews restrict their literature searches when only studies from Germany should be included?

    Science.gov (United States)

    Pieper, Dawid; Mathes, Tim; Palm, Rebecca; Hoffmann, Falk

    2016-11-01

    The use of search filters (e. g. for study types) facilitates the process of literature searching. Regional limits might be helpful depending on the research question. Regional search filters are already available for some regions, but not for Germany. Our aim is to give an overview of applied search strategies in systematic reviews (SRs) focusing on Germany. We searched Medline (via Pubmed) applying a focused search strategy to identify SRs focusing on Germany in January 2016. Study selection and data extraction were performed by two reviewers independently. The search strategies with a focus on Germany were analyzed in terms of reasonableness and completeness relying on the Peer Review of Electronic Search Strategies (PRESS) criteria. A narrative evidence synthesis was performed. In total, 36 SRs (13 written in English) were included. 78% were published in 2012 or later. The majority (89%) of SRs utilized at least two different sources for their search with databases and checking references being the most common. 17 SRs did not use any truncations, ten SRs did not restrict their search to Germany, six SRs reported to have searched for German OR Germany. Only ten articles searched for the term Germany (occasionally jointly with the term Deutschland) without any use of an adjective such as German. There is a high interest in regionally focused SRs. The identified search strategies revealed a need for improvement. It would be helpful to develop a regional search filter for Germany that is able to identify studies performed in Germany. Copyright © 2016. Published by Elsevier GmbH.

  2. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Branka I Ognjanović. Articles written in Journal of Biosciences. Volume 39 Issue 5 December 2014 pp 859-866 Articles. Prooxidative effects of aspartame on antioxidant defense status in erythrocytes of rats · Marko D Prokić Milica G Paunović Miloš M Matić Nataša Z Djordjević ...

  3. What is lost when searching only one literature database for articles relevant to injury prevention and safety promotion?

    Science.gov (United States)

    Lawrence, D W

    2008-12-01

    To assess what is lost if only one literature database is searched for articles relevant to injury prevention and safety promotion (IPSP) topics. Serial textword (keyword, free-text) searches using multiple synonym terms for five key IPSP topics (bicycle-related brain injuries, ethanol-impaired driving, house fires, road rage, and suicidal behaviors among adolescents) were conducted in four of the bibliographic databases that are most used by IPSP professionals: EMBASE, MEDLINE, PsycINFO, and Web of Science. Through a systematic procedure, an inventory of articles on each topic in each database was conducted to identify the total unduplicated count of all articles on each topic, the number of articles unique to each database, and the articles available if only one database is searched. No single database included all of the relevant articles on any topic, and the database with the broadest coverage differed by topic. A search of only one literature database will return 16.7-81.5% (median 43.4%) of the available articles on any of five key IPSP topics. Each database contributed unique articles to the total bibliography for each topic. A literature search performed in only one database will, on average, lead to a loss of more than half of the available literature on a topic.

  4. Support needs of patients with COPD: a systematic literature search and narrative review.

    Science.gov (United States)

    Gardener, A Carole; Ewing, Gail; Kuhn, Isla; Farquhar, Morag

    2018-01-01

    Understanding the breadth of patients' support needs is important for the delivery of person-centered care, particularly in progressive long-term conditions such as chronic obstructive pulmonary disease (COPD). Existing reviews identify important aspects of managing life with COPD with which patients may need support (support needs); however, none of these comprehensively outlines the full range of support needs that patients can experience. We therefore sought to systematically determine the full range of support needs for patients with COPD to inform development of an evidence-based tool to enable person-centered care. We conducted a systematic search and narrative review of the literature. Medline (Ovid), EMBASE, PsycINFO, Cochrane Library, and CINAHL were systematically searched for papers which included data addressing key aspects of support need, as identified by patients with COPD. Relevant data were extracted, and a narrative analysis was conducted. Thirty-one papers were included in the review, and the following 13 domains (broad areas) of support need were identified: 1) understanding COPD, 2) managing symptoms and medication, 3) healthy lifestyle, 4) managing feelings and worries, 5) living positively with COPD, 6) thinking about the future, 7) anxiety and depression, 8) practical support, 9) finance work and housing, 10) families and close relationships, 11) social and recreational life, 12) independence, and 13) navigating services. These 13 domains of support need were mapped to three of the four overarching categories of need commonly used in relevant national strategy documents (ie, physical, psychological, and social); however, support needs related to the fourth category (spiritual) were notably absent. This review systematically identifies the comprehensive set of domains of support need for patients with COPD. The findings provide the evidence base for a tool to help patients identify and express their support needs, which underpins a proposed

  5. East Midlands healthcare and bioscience sector strategy appendix 1: healthcare and bioscience res implementation plan

    OpenAIRE

    East Midlands Development Agency

    2007-01-01

    The healthcare and bioscience sector is one of four priority sectors identified in the regional economic strategy, A Flourishing Region. This document sets out the implementation plan for maximising the contribution of the healthcare and biosciences sector to the economic development of the East Midlands.

  6. Paranormal phenomena in the medical literature sufficient smoke to warrant a search for fire.

    Science.gov (United States)

    Bobrow, Robert S

    2003-06-01

    Paranormal phenomena - events that cannot be explained by existing science - are regularly reported in medicine. Surveys have shown that a majority of the population of the United States and Great Britain hold at least one paranormal belief. Information was retrieved by MEDLINE searches using keywords 'paranormal' and 'psychic', and from the author's own collection. Reports are predominantly by physicians, and from peer-reviewed, MEDLINE-indexed literature. This is a representative sample, as there is no database for paranormal medical phenomena. Presented and discussed are: a case of systemic lupus erythematosis ameliorated by witchcraft; an analysis of studies on distant healing; acupuncture, as a bridge between what is now accepted but recently would have been deemed paranormal; a carefully-done study of a psychic; auditory hallucinations informing a patient, correctly, that she had a brain tumor; two nearly-identical lay press reports of self-predicted death; lycanthropy (the delusion of being an animal); the development of Carl Jung's collective unconscious; hypnosis - still questioned despite documented therapeutic benefit, and a well-researched report of a person speaking a foreign language, apparently unlearned (xenoglossy) while hypnotized; and multiple examples of children who spout the details of the life of an unknown, deceased person. The inability of existing paradigms to explain these observations does not negate them; rather, it elucidates a need for more research.

  7. Search for the lowest irradiation dose from literatures on radiation-induced cancer in uterus

    International Nuclear Information System (INIS)

    Yoshizawa, Yasuo; Kusama, Tomoko

    1975-01-01

    A survey of past case reports on radiation-induced cancer of the uterus was carried out with the main object of finding the lowest irradiation dose. Search of literature published since 1912 revealed 548 cases of radiation-induced cancer of the uterus. All of these cases of radiation-induced cancer had received radiation for the treatment of non-malignant disease. The primary gynecological conditions which were the object of radiation therapy were functional bleeding, endometrial hyperplasia, myoma, endometritis, and polyps. The lowest irradiation dose was estimated at 1000-1450 rad in the case of external X-ray irradiation, and 100 mg.hr for intrauterine radium therapy, which corresponds to 100-1000 rad. It was noted that were more cases of corpus cancer than cervical cancer. Histopathological findings of radiation-induced uterine cancer were carcinoma, sarcoma, and mixed mesodermal tumors. The latent period was distributed in the range of 1 to 40 years, with the average of 10.1 years. (auth.)

  8. Search for the lowest irradiation dose from literatures on radiation-induced cancer in gastrointestinal tract

    International Nuclear Information System (INIS)

    Yoshizawa, Yasuo; Kusama, Tomoko

    1976-01-01

    A survey of past case reports about radiation-induced cancer in the gastrointestinal tract was carried out with the main object of finding the lowest irradiation dose. Search of the literature published since 1923 revealed 80 cases of radiation-induced large intestine cancer and one case of stomach cancer. The cases of radiation-induced cancer in the large intestine had received radiation for the treatment of non-malignant conditions, fibroma, ovarial cyste, myoma, endometritis and duodenal ulcer. The lowest irradiation dose was estimated at 460 rads. Adenocarcinoma was the histopathological finding in all cases of radiation-induced cancer in the caecum, colon and rectum, and squamous cell carcinoma in the cases of anal cancer. The latent period ranged from 1 to 31 years, with the average of 13.6 years. There were some reports of statistical studies of radiation-induced stomach cancer. Three groups were the subjects of these studies. The first group was composed of atomic bomb survivors, the second of patients who had undergone radiation treatment for ankylosing spondilitis, and the third of duodenal ulcer patients subjected to radiation treatment for the purpose of suppressing gastric acid secretion. These statistical studies showed no significant increase of the incidence of stomach cancer in the irradiated groups. (auth.)

  9. Methodology Used to Assess Acceptability of Oral Pediatric Medicines: A Systematic Literature Search and Narrative Review.

    Science.gov (United States)

    Mistry, Punam; Batchelor, Hannah

    2017-06-01

    Regulatory guidelines require that any new medicine designed for a pediatric population must be demonstrated as being acceptable to that population. There is currently no guidance on how to conduct or report on acceptability testing. Our objective was to undertake a review of the methods used to assess the acceptability of medicines within a pediatric population and use this review to propose the most appropriate methodology. We used a defined search strategy to identify literature reports of acceptability assessments of medicines conducted within pediatric populations and extracted information about the tools used in these studies for comparison across studies. In total, 61 articles were included in the analysis. Palatability was the most common (54/61) attribute measured when evaluating acceptability. Simple scale methods were most commonly used, with visual analog scales (VAS) and hedonic scales used both separately and in combination in 34 of the 61 studies. Hedonic scales alone were used in 14 studies and VAS alone in just five studies. Other tools included Likert scales; forced choice or preference; surveys or questionnaires; observations of facial expressions during administration, ease of swallowing, or ability to swallow the dosage; prevalence of complaints or refusal to take the medicine; and time taken for a nurse to administer the medicine. The best scale in terms of validity, reliability, feasibility, and preference to use when assessing acceptability remains unclear. Further work is required to select the most appropriate method to justify whether a medicine is acceptable to a pediatric population.

  10. PubMed Phrases, an open set of coherent phrases for searching biomedical literature

    Science.gov (United States)

    Kim, Sun; Yeganova, Lana; Comeau, Donald C.; Wilbur, W. John; Lu, Zhiyong

    2018-01-01

    In biomedicine, key concepts are often expressed by multiple words (e.g., ‘zinc finger protein’). Previous work has shown treating a sequence of words as a meaningful unit, where applicable, is not only important for human understanding but also beneficial for automatic information seeking. Here we present a collection of PubMed® Phrases that are beneficial for information retrieval and human comprehension. We define these phrases as coherent chunks that are logically connected. To collect the phrase set, we apply the hypergeometric test to detect segments of consecutive terms that are likely to appear together in PubMed. These text segments are then filtered using the BM25 ranking function to ensure that they are beneficial from an information retrieval perspective. Thus, we obtain a set of 705,915 PubMed Phrases. We evaluate the quality of the set by investigating PubMed user click data and manually annotating a sample of 500 randomly selected noun phrases. We also analyze and discuss the usage of these PubMed Phrases in literature search. PMID:29893755

  11. Search for the lowest irradiation dose from literatures on radiation-induced cancer in gastrointestinal tract

    Energy Technology Data Exchange (ETDEWEB)

    Yoshizawa, Y; Kusama, T [Tokyo Univ. (Japan). Faculty of Medicine

    1976-05-01

    A survey of past case reports about radiation-induced cancer in the gastrointestinal tract was carried out with the main object of finding the lowest irradiation dose. Search of the literature published since 1923 revealed 80 cases of radiation-induced large intestine cancer and one case of stomach cancer. The cases of radiation-induced cancer in the large intestine had received radiation for the treatment of non-malignant conditions, fibroma, ovarial cyste, myoma, endometritis and duodenal ulcer. The lowest irradiation dose was estimated at 460 rads. Adenocarcinoma was the histopathological finding in all cases of radiation-induced cancer in the caecum, colon and rectum, and squamous cell carcinoma in the cases of anal cancer. The latent period ranged from 1 to 31 years, with the average of 13.6 years. There were some reports of statistical studies of radiation-induced stomach cancer. Three groups were the subjects of these studies. The first group was composed of atomic bomb survivors, the second of patients who had undergone radiation treatment for ankylosing spondilitis, and the third of duodenal ulcer patients subjected to radiation treatment for the purpose of suppressing gastric acid secretion. These statistical studies showed no significant increase of the incidence of stomach cancer in the irradiated groups.

  12. Search for the lowest irradiation dose from literatures on radiation-induced breast cancer

    Energy Technology Data Exchange (ETDEWEB)

    Yoshizawa, Y; Kusama, T [Tokyo Univ. (Japan). Faculty of Medicine

    1975-12-01

    A survey of past case reports concerning radiation-induced breast cancer was carried out in order to find the lowest irradiation dose. The search of literature published since 1951 revealed 10 cases of radiation-induced breast cancer. Only 5 cases had precise descriptions of the irradiation dose. The lowest irradiation dose was estimated at 1470 rads in the case of external X-ray irradiation for tuberous angioma. All of cases of radiation-induced breast cancer had received radiation for the treatment of nonmalignant tumors, such as pulmonary tuberculosis, mastitis, and tuberous angioma. There also were three statistical studies. The first concerned atomic bomb survivors, the second, pulmoanry tuberculous patients subjected to frequent fluoroscopies, and the third, patients of acute post partum mastitis. These statistical studies had revealed a significant increase in the incidence of breast cancer in the irradiated group, but there was little information about the lowest irradiation dose. It was noticed that radiation-induced breast cancer was more numerous in the upper inner quadrant of the breast. Most histopathological findings of radiation-induced breast cancer involved duct cell carcinoma. The latent period was about 15 years.

  13. Search for the lowest irradiation dose from literatures on radiation-induced bone tumor

    Energy Technology Data Exchange (ETDEWEB)

    Yoshizawa, Y; Kusama, T; Morimoto, K [Tokyo Univ. (Japan). Faculty of Medicine

    1977-04-01

    A survey of past case reports of bone tumor induced by external radiation was carried out with the main object of finding the lowest irradiation dose. Search of the literature published since 1922 revealed 262 cases of radiation-induced bone tumor. These patients, except a patient with occupational exposure, had received radiation for treatment. The primary conditions as object of radiation therapy were nonmalignan bone diseases such as tuberclosis, giant cell tumor, fibrous dysplasia and bone cyst, and extra-skeletal diseases such as retinoblastoma, breast cancer and uterus cancer. The ratio of male to female patients with radiation-induced bone tumor was 1:1.3. The age of the patient ranged between 5 and 98 years, with an average of 37.6 years. Skeletal distribution of radiation-induced bone tumor was as follows: 20% the frontal and face bones, 17% the femur, 10% the humerus, 9% the vertebral column, and 44% other. The lowest absorbed dose reported was 800 rads in patients irradiated for the treatment of bone disease, but 1800 rads in patients with extra-skeletal disease. The latent period ranged between 2 and 42 years, with an average of 11.7 years. The histopathological findings were as follows: 60% osteosarcoma, 25% fibrosarcoma, 7% chondrosarcoma, and 8% other.

  14. Testing search strategies for systematic reviews in the Medline literature database through PubMed.

    Science.gov (United States)

    Volpato, Enilze S N; Betini, Marluci; El Dib, Regina

    2014-04-01

    A high-quality electronic search is essential in ensuring accuracy and completeness in retrieved records for the conducting of a systematic review. We analysed the available sample of search strategies to identify the best method for searching in Medline through PubMed, considering the use or not of parenthesis, double quotation marks, truncation and use of a simple search or search history. In our cross-sectional study of search strategies, we selected and analysed the available searches performed during evidence-based medicine classes and in systematic reviews conducted in the Botucatu Medical School, UNESP, Brazil. We analysed 120 search strategies. With regard to the use of phrase searches with parenthesis, there was no difference between the results with and without parenthesis and simple searches or search history tools in 100% of the sample analysed (P = 1.0). The number of results retrieved by the searches analysed was smaller using double quotations marks and using truncation compared with the standard strategy (P = 0.04 and P = 0.08, respectively). There is no need to use phrase-searching parenthesis to retrieve studies; however, we recommend the use of double quotation marks when an investigator attempts to retrieve articles in which a term appears to be exactly the same as what was proposed in the search form. Furthermore, we do not recommend the use of truncation in search strategies in the Medline via PubMed. Although the results of simple searches or search history tools were the same, we recommend using the latter.

  15. Extensive literature searches soil and growing media inventories : (RC/EFSA/PLH/2013/01-SC1)

    NARCIS (Netherlands)

    Bremmer, J.; Holeva, M.; Breukers, M.L.H.; Brouwer, J.H.D.

    2015-01-01

    In this project two inventories by means of extensive literature searches have been executed: Inventory 1 of all types of soil and growing media (if relevant components thereof) to be elaborated considering (i) the soil and growing medium imported as commodities (i.e. not in association with plants

  16. Muscle Logic: New Knowledge Resource for Anatomy Enables Comprehensive Searches of the Literature on the Feeding Muscles of Mammals.

    Directory of Open Access Journals (Sweden)

    Robert E Druzinsky

    Full Text Available In recent years large bibliographic databases have made much of the published literature of biology available for searches. However, the capabilities of the search engines integrated into these databases for text-based bibliographic searches are limited. To enable searches that deliver the results expected by comparative anatomists, an underlying logical structure known as an ontology is required.Here we present the Mammalian Feeding Muscle Ontology (MFMO, a multi-species ontology focused on anatomical structures that participate in feeding and other oral/pharyngeal behaviors. A unique feature of the MFMO is that a simple, computable, definition of each muscle, which includes its attachments and innervation, is true across mammals. This construction mirrors the logical foundation of comparative anatomy and permits searches using language familiar to biologists. Further, it provides a template for muscles that will be useful in extending any anatomy ontology. The MFMO is developed to support the Feeding Experiments End-User Database Project (FEED, https://feedexp.org/, a publicly-available, online repository for physiological data collected from in vivo studies of feeding (e.g., mastication, biting, swallowing in mammals. Currently the MFMO is integrated into FEED and also into two literature-specific implementations of Textpresso, a text-mining system that facilitates powerful searches of a corpus of scientific publications. We evaluate the MFMO by asking questions that test the ability of the ontology to return appropriate answers (competency questions. We compare the results of queries of the MFMO to results from similar searches in PubMed and Google Scholar.Our tests demonstrate that the MFMO is competent to answer queries formed in the common language of comparative anatomy, but PubMed and Google Scholar are not. Overall, our results show that by incorporating anatomical ontologies into searches, an expanded and anatomically comprehensive

  17. Muscle Logic: New Knowledge Resource for Anatomy Enables Comprehensive Searches of the Literature on the Feeding Muscles of Mammals.

    Science.gov (United States)

    Druzinsky, Robert E; Balhoff, James P; Crompton, Alfred W; Done, James; German, Rebecca Z; Haendel, Melissa A; Herrel, Anthony; Herring, Susan W; Lapp, Hilmar; Mabee, Paula M; Muller, Hans-Michael; Mungall, Christopher J; Sternberg, Paul W; Van Auken, Kimberly; Vinyard, Christopher J; Williams, Susan H; Wall, Christine E

    2016-01-01

    In recent years large bibliographic databases have made much of the published literature of biology available for searches. However, the capabilities of the search engines integrated into these databases for text-based bibliographic searches are limited. To enable searches that deliver the results expected by comparative anatomists, an underlying logical structure known as an ontology is required. Here we present the Mammalian Feeding Muscle Ontology (MFMO), a multi-species ontology focused on anatomical structures that participate in feeding and other oral/pharyngeal behaviors. A unique feature of the MFMO is that a simple, computable, definition of each muscle, which includes its attachments and innervation, is true across mammals. This construction mirrors the logical foundation of comparative anatomy and permits searches using language familiar to biologists. Further, it provides a template for muscles that will be useful in extending any anatomy ontology. The MFMO is developed to support the Feeding Experiments End-User Database Project (FEED, https://feedexp.org/), a publicly-available, online repository for physiological data collected from in vivo studies of feeding (e.g., mastication, biting, swallowing) in mammals. Currently the MFMO is integrated into FEED and also into two literature-specific implementations of Textpresso, a text-mining system that facilitates powerful searches of a corpus of scientific publications. We evaluate the MFMO by asking questions that test the ability of the ontology to return appropriate answers (competency questions). We compare the results of queries of the MFMO to results from similar searches in PubMed and Google Scholar. Our tests demonstrate that the MFMO is competent to answer queries formed in the common language of comparative anatomy, but PubMed and Google Scholar are not. Overall, our results show that by incorporating anatomical ontologies into searches, an expanded and anatomically comprehensive set of results

  18. Optimal database combinations for literature searches in systematic reviews : a prospective exploratory study

    NARCIS (Netherlands)

    Bramer, W. M.; Rethlefsen, Melissa L.; Kleijnen, Jos; Franco, Oscar H.

    2017-01-01

    Background: Within systematic reviews, when searching for relevant references, it is advisable to use multiple databases. However, searching databases is laborious and time-consuming, as syntax of search strategies are database specific. We aimed to determine the optimal combination of databases

  19. Evaluation of a new method for librarian-mediated literature searches for systematic reviews

    NARCIS (Netherlands)

    W.M. Bramer (Wichor); Rethlefsen, M.L. (Melissa L.); F. Mast (Frans); J. Kleijnen (Jos)

    2017-01-01

    textabstractObjective: To evaluate and validate the time of completion and results of a new method of searching for systematic reviews, the exhaustive search method (ESM), using a pragmatic comparison. Methods: Single-line search strategies were prepared in a text document. Term completeness was

  20. Support needs of patients with COPD: a systematic literature search and narrative review

    Directory of Open Access Journals (Sweden)

    Gardener AC

    2018-03-01

    Full Text Available A Carole Gardener,1 Gail Ewing,2 Isla Kuhn,3 Morag Farquhar4 1Primary Care Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK; 2Centre for Family Research, University of Cambridge, Cambridge, UK; 3University of Cambridge Medical School Library, University of Cambridge, Cambridge, UK; 4School of Health Sciences, University of East Anglia, Norwich, UK Introduction: Understanding the breadth of patients’ support needs is important for the delivery of person-centered care, particularly in progressive long-term conditions such as chronic obstructive pulmonary disease (COPD. Existing reviews identify important aspects of managing life with COPD with which patients may need support (support needs; however, none of these comprehensively outlines the full range of support needs that patients can experience. We therefore sought to systematically determine the full range of support needs for patients with COPD to inform development of an evidence-based tool to enable person-centered care.Methods: We conducted a systematic search and narrative review of the literature. Medline (Ovid, EMBASE, PsycINFO, Cochrane Library, and CINAHL were systematically searched for papers which included data addressing key aspects of support need, as identified by patients with COPD. Relevant data were extracted, and a narrative analysis was conducted.Results: Thirty-one papers were included in the review, and the following 13 domains (broad areas of support need were identified: 1 understanding COPD, 2 managing symptoms and medication, 3 healthy lifestyle, 4 managing feelings and worries, 5 living positively with COPD, 6 thinking about the future, 7 anxiety and depression, 8 practical support, 9 finance work and housing, 10 families and close relationships, 11 social and recreational life, 12 independence, and 13 navigating services. These 13 domains of support need were mapped to three of the four overarching categories of need

  1. Novel citation-based search method for scientific literature: application to meta-analyses

    NARCIS (Netherlands)

    Janssens, A.C.J.W.; Gwinn, M.

    2015-01-01

    Background: Finding eligible studies for meta-analysis and systematic reviews relies on keyword-based searching as the gold standard, despite its inefficiency. Searching based on direct citations is not sufficiently comprehensive. We propose a novel strategy that ranks articles on their degree of

  2. Expert searching in health librarianship: a literature review to identify international issues and Australian concerns.

    Science.gov (United States)

    Lasserre, Kaye

    2012-03-01

    The traditional role of health librarians as expert searchers is under challenge. The purpose of this review is to establish health librarians' views, practices and educational processes on expert searching. The search strategy was developed in LISTA and then customised for ten other databases: ALISA, PubMed, Embase, Scopus, Web of Science, CINAHL, ERIC, PsycINFO, Cochrane Library and Google Scholar. The search terms were (expert search* OR expert retriev* OR mediated search* OR information retriev*) AND librar*. The searches, completed in December 2010 and repeated in May 2011, were limited to English language publications from 2000 to 2011 (unless seminal works). Expert searching remains a key role for health librarians, especially for those supporting systematic reviews or employed as clinical librarians answering clinical questions. Although clients tend to be satisfied with searches carried out for them, improvements are required to effectively position the profession. Evidence-based guidelines, adherence to transparent standards, review of entry-level education requirements and a commitment to accredited, rigorous, ongoing professional development will ensure best practice. © 2012 The authors. Health Information and Libraries Journal © 2012 Health Libraries Group.

  3. Environmental Biosciences Program Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2006-10-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this cooperative agreement can be forwarded to Dr. Lawrence C. Mohr in the EBP office of the Medical University of South Carolina at (843) 792-1532.

  4. Environmental Biosciences First Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2003-09-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risk issues. These initiatives are consistent with the Medical University's role as a comprehensive state-supported health sciences institution and the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable the Medical University to be a national resource for the scientific investigation of environmental health issues. EBP's success in convening worldwide scientific expertise is due in part to the inherent credibility the Medical University brings to the process of addressing these complex issues. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), asbestos and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  5. Environmental Biosciences Program Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2007-07-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the DOE. Plans for restructuring the performance schedule of the trichloroethylene projects have been submitted to the department. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this

  6. Environmental Biosciences Program Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2008-01-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the DOE. Plans for restructuring the performance schedule of the trichloroethylene projects have been submitted to the department. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  7. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2009-08-19

    Aug 19, 2009 ... Home; Journals; Journal of Biosciences; Volume 34; Issue 3. What history tells us XVIII. When functional biologists propose mechanisms of evolution. Michel Morange. Series Volume 34 Issue 3 September 2009 pp 373-376. Fulltext. Click here to view fulltext PDF. Permanent link:

  8. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 40; Issue 5. Comparative sequence analyses of genome and transcriptome reveal novel transcripts and variants in the Asian elephant Elephas maximus. Puli Chandramouli Reddy Ishani Sinha Ashwin Kelkar Farhat Habib Saurabh J Pradhan Raman Sukumar Sanjeev ...

  9. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 40; Issue 3. A rapidly progressing, deadly disease of Actias selene (Indianmoonmoth) larvae associated with a mixed bacterial and baculoviral infection. Marta A Skowron Beata Guzow-Krzemińska Sylwia Barańska Paulina Jędrak Grzegorz Węgrzyn. Articles Volume 40 ...

  10. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 40; Issue 5. Issue front cover thumbnail. Volume 40, Issue 5. December 2015, pages 829-968. pp 829-832 Series. What history tells us XXXIX. CRISPR-Cas : From a prokaryotic immune system to a universal genome editing tool · Michel Morange · More Details Fulltext PDF.

  11. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 35; Issue 2. Issue front cover thumbnail. Volume 35, Issue 2. June 2010, pages 163-325. pp 163-165. Clipboard: Heat shock protein 90: a capacitor or a mutator? Ritwick Sawarkar Renato Paro · More Details Fulltext PDF. pp 167-169. Clipboard: The small subunit of geranyl ...

  12. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 43; Issue 2 ... The ErbB signalling pathway has been studied extensively owing to its role in normal physiology ... When applied to drug studies, the efficacy of a drug can be investigated in silico ...

  13. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 27; Issue 4 ... areas, so the data used to make such comparisons should be comparable in quality and quantity. ... data include museums, herbariums and natural resource management agencies. Issues of data precision, accuracy and sampling bias in data sets from such ...

  14. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 41; Issue 3 .... HUWE1 (the HECT, UBA, and WWE domain-containing protein 1) is an ubiquitin E3 ligase which plays .... pp 487-496 Review ... Galectin-9: From cell biology to complex disease dynamics ... Application of aptamers in diagnostics, drug-delivery and imaging.

  15. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 41; Issue 2. Effects of quercetin on predator stress-related hematological and behavioral alterations in pregnant rats and their offspring. Mohamed ... Keywords. Prenatal stress; Anxiety-like behavior; Memory performance; Hematological analysis; Periadolescence; Quercetin ...

  16. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 33; Issue 2. Issue front cover thumbnail. Volume 33, Issue 2. June 2008, pages 157-307. pp 157-158. Clipboard: Recovery from amblyopia in adults via decreased visual cortical inhibition caused by experience in an enriched environment · Liisa A Tremere Raphael Pinaud.

  17. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2007-02-09

    Feb 9, 2007 ... Home; Journals; Journal of Biosciences; Volume 32; Issue 2. What history tells us VIII. The progressive construction of a mechanism for prion diseases. Michel Morange. Series Volume 32 Issue 2 March 2007 pp 223-227. Fulltext. Click here to view fulltext PDF. Permanent link:

  18. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2009-09-04

    Sep 4, 2009 ... Home; Journals; Journal of Biosciences; Volume 34; Issue 4. Helicobacter urease: Niche construction at the single molecule level ... Departments of Lifesciences and # Computer Science, School of Science and Engineering, Lahore University of Management Sciences, Lahore 54792, Punjab, Pakistan ...

  19. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Logo of the Indian Academy of Sciences ... Home; Journals; Journal of Biosciences; Volume 28; Issue 1 ... Department of Safety and Environmental Management, College of Engineering and Mineral Resources, Morgantown, WV 26506, USA; Health Effects Laboratory Division, National Institute for Occupational Safety and ...

  20. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2008-12-09

    Dec 9, 2008 ... Home; Journals; Journal of Biosciences; Volume 34; Issue 4. Phenotypic plasticity ... Articles Volume 34 Issue 4 October 2009 pp 605-611 ... Stem cell immortality, vascular autonomy, and epicormic branching are some important features of the phenotypic plasticity of plants that contribute to their longevity.

  1. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Centro de Desenvolvimento Tecnológico, Universidade Federal de Pelotas, CP 354, 96010-900, Pelotas, RS, Brazil; Faculty of Biosciences and Aquaculture, Bodø University College, NO-8049 Bodø, Norway; Laboratório de Biologia Molecular, Instituto de Ciências Biológicas, Universidade Federal do Rio Grande, CP 474, ...

  2. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 42; Issue 1. What history tells us XLII. A 'new' view of proteins. MICHEL MORANGE. Series Volume 42 Issue 1 March 2017 pp 11-14. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/jbsc/042/01/0011-0014. Keywords. Allostery ...

  3. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2008-10-15

    Oct 15, 2008 ... Home; Journals; Journal of Biosciences; Volume 33; Issue 4. Combating emerging infectious diseases in India: Orchestrating a symphony. Lalit Kant. Volume 33 Issue 4 November 2008 pp 425-427. Fulltext. Click here to view fulltext PDF. Permanent link:

  4. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 27; Issue 1. Issue front cover thumbnail. Volume 27, Issue 1. February 2002, pages a-70. Genome Analysis. pp a-a. Preface · Alok Bhattacharya · More Details Fulltext PDF. pp 1-6. SWORDS: A statistical tool for analysing large DNA sequences · Probal Chaudhuri Sandip Das.

  5. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Here two very different kinds of organisms are considered: the volvocine algae that become ... that there is a perfect correlation with size: the forms with two cell types are significantly larger than those with one. ... Journal of Biosciences | News ...

  6. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 42; Issue 3 ... miR-200a-3p have been reported in the brains of Alzheimer'sdisease (AD) patients in recent researches. ... Knockdown of SIRT1 decreased theinhibitory effect of Ab25-35 on cell ...

  7. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 37; Issue 4. Commentary: Monotremes and marsupials: Comparative models to better understand the function of milk. Sanjana Kuruppath Swathi Bisana Julie A Sharp Christophe Lefevre Satish Kumar Kevin R Nicholas. Volume 37 Issue 4 September 2012 pp 581-588 ...

  8. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 37; Issue 4. Changes in membrane lipids and carotenoids during light acclimation in a marine cyanobacterium Synechococcus sp. Olimpio Montero Alberto Sánchez-Guijo Luis M Lubián Gonzalo Martínez-Rodríguez. Articles Volume 37 Issue 4 September 2012 pp 635-645 ...

  9. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 31; Issue 2. Issue front cover thumbnail. Volume 31, Issue 2. June 2006, pages 177-292. pp 177-179. Clipboard: Simple laboratory tests of ecological theories: what we can learn from them, and when we should be cautious · Mike S Fowler Lasse Ruokolainen · More Details ...

  10. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Alok Bhattacharya1. School of Life Sciences and Information Technology, Jawaharlal Nehru University, New Delhi 110 007, India. Journal of Biosciences. Current Issue : Vol. 43, Issue 1 · Current Issue Volume 43 | Issue 1. March 2018. Home · Volumes & Issues · Special Issues · Forthcoming Articles · Gallery of Cover Art ...

  11. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 41; Issue 2. Toward the 'new century' of handedness in biology: In commemoration of the 100th anniversary of the birth of Francis Crick. Koji Tamura. Clipboard Volume 41 Issue 2 June 2016 pp 169-170 ...

  12. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 31; Issue 2. Genetic transformation of peanut (Arachis hypogaea L.) using cotyledonary node as explant and a promoterless gus::nptII fusion gene based vector. T Swathi Anuradha S K Jami R S Datla P B Kirti. Articles Volume 31 Issue 2 June 2006 pp 235-246 ...

  13. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 26; Issue 4. Is there a role for contraceptive vaccines in fertility control? A Jagannadha Rao. Volume 26 Issue 4 November 2001 pp 425-427. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/jbsc/026/04/0425-0427. Keywords. Fertility ...

  14. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 28; Issue 6. A skeletochronological study of growth, longevity, and age at sexual maturity in a population of Rana latastei (Amphibia, Anura). Fabio M Guarino Silvia Lunardi Michela Carlomagno Stefano Mazzotti. Articles Volume 28 Issue 6 December 2003 pp 775-782 ...

  15. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2011-03-14

    Mar 14, 2011 ... Home; Journals; Journal of Biosciences; Volume 36; Issue 1. Clipboard: New paradigm for ATP synthesis and consumption. C Channakeshava. Volume 36 Issue 1 March 2011 pp 3-4. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/jbsc/036/01/0003-0004 ...

  16. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 28; Issue 3. Issue front cover thumbnail. Volume 28, Issue 3. April 2003, pages 248-358. Viral Evasion of Host Responses. pp 248-248. Preface · Shahid Jameel · More Details Fulltext PDF. pp 249-264 Articles. Viral mimicry of the complement system · John Bernet Jayati ...

  17. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 27; Issue 6. Issue front cover thumbnail. Volume 27, Issue 6. November 2002, pages 552-627. Special Issue on Suppl. 3: The Biology of Entamoeba histolytica. pp 552-552a. Preface · Anuradha Lohia · More Details Fulltext PDF. pp 553-557 Articles.

  18. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2009-12-09

    Dec 9, 2009 ... Home; Journals; Journal of Biosciences; Volume 34; Issue 6 ... and suitable teaching methods have been of great importance in the progress of knowledge. ... And what is valid for the learning of anatomy can be generalized to ...

  19. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 32; Issue 4. Molecular cloning and expression of the C-terminus of spider flagelliform silk protein from Araneus ventricosus. Kwang Sik Lee Bo Yeon Kim Yeon Ho Je Soo Dong Woo Hung Dae Sohn Byung Rae Jin. Articles Volume 32 Issue 4 June 2007 pp 705-712 ...

  20. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 34; Issue 6. Identification and ... Alignment and phylogenetic analysis indicated that GbAGL2 shared high homology with AG-subfamily genes and belonged to a C-class gene family. DNA gel blot analysis showed that GbAGL2 belonged to a low-copy gene family. Reverse ...

  1. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 36; Issue 1. P1 peptidase – a mysterious protein of family Potyviridae. Jana Rohožková Milan Navrátil ... The coding region for P1 peptidase is located at the very beginning of the viral genome of the family Potyviridae. Until recently P1 was thought of as serine peptidase with ...

  2. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 36; Issue 4. RET gene mutations and ... Articles Volume 36 Issue 4 September 2011 pp 603-611 ... Further, 39 family members of seven index cases were analysed, wherein four of the seven index cases showed identical mutations, in 13 of 25 family members. We also ...

  3. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 36; Issue 2. Splicing ... Articles Volume 36 Issue 2 June 2011 pp 281-287 ... One proband had mutation at the canonical splice site at +5 position of IVS22, and analysis of the transcripts in this family revealed skipping of exon 22 in three members of this family. In one proband ...

  4. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 34; Issue 2 ... Review Volume 34 Issue 2 June 2009 pp 313-320 ... Matrix metalloproteinases (MMPs) are a family of zinc (Zn)-dependent endopeptidases that are collectively capable of cleaving virtually all extracellular matrix (ECM) substrates and play an important role in ...

  5. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 42; Issue 1. Diverse roles of WDR5-RbBP5-ASH2L-DPY30 (WRAD) complex in the functions of the SET1 histone methyltransferase family. AAMIR ALI SHWETA TYAGI. Mini-Review Volume 42 Issue 1 ... Keywords. Cell cycle regulation; SET1 family; transcription; WRAD ...

  6. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 39; Issue 5. Evolution and expression analysis of the soybean glutamate decarboxylase gene family ... Although plant GAD plays important roles in GABA biosynthesis, our knowledge concerning GAD gene family members and their evolutionary relationship remains limited.

  7. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2009-02-24

    Feb 24, 2009 ... Home; Journals; Journal of Biosciences; Volume 34; Issue 1. Classical embryology to molecular biology: a personal view of amphibian embryonic development. Horst Grunz. Perspectives Volume 34 Issue 1 March 2009 pp 5-16. Fulltext. Click here to view fulltext PDF. Permanent link:

  8. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 28; Issue 4. Hypervariable spacer regions are good sites for developing specific PCR-RFLP markers and PCR primers for screening actinorhizal symbionts. Rajani Varghese Vineeta S Chauhan Arvind K Misra. Articles Volume 28 Issue 4 June 2003 pp 437-442 ...

  9. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 33; Issue 1 ... In the present investigation, we evaluated the level of platelet aggregation and ... cirrhosis found in our study is of clinical importance, and the underlying mechanism of such ... Department of Surgical Gastroenterology and Proctology, Stanley Medical College ...

  10. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 26; Issue 4. Issue front cover thumbnail. Volume 26, Issue 4. November 2001, pages 390a-545. Population of India. pp 390a-390a. Preface · Partha P Majumder A Jagannadha Rao · More Details Fulltext PDF. pp 391-405. Current status of fertility control methods in India.

  11. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 34; Issue 2 .... mapping, expression analysis and polymorphism survey of resistance gene analogues ... However, due to inconsistency in the results of empirical studies, the relationship between FA and ... MMP-1 polymorphism and its relationship to pathological processes.

  12. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2009-05-18

    May 18, 2009 ... Home; Journals; Journal of Biosciences; Volume 34; Issue 2. Clipboard: Snakes and ladders: the ups and downs of animal segmentation. Ramray Bhat Stuart A Newman. Volume 34 Issue 2 June 2009 pp 163-166. Fulltext. Click here to view fulltext PDF. Permanent link:

  13. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 31; Issue 5. Combinative effects of a bacterial type-III effector and a biocontrol bacterium on rice growth and disease resistance. Haiying Ren Ganyu Gu Juying Long Qian Yin Tingquan Wu Tao Song Shujian Zhang Zhiyi Chen Hansong Dong. Reviews Volume 31 Issue 5 ...

  14. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 36; Issue 4. Eu-Detect: An algorithm for detecting eukaryotic sequences in metagenomic data sets. Monzoorul Haque Mohammed Sudha Chadaram Dinakar Dinakar Komanduri Tarini Shankar Ghosh Sharmila S Mande. Articles Volume 36 Issue 4 September 2011 pp 709- ...

  15. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 28; Issue 4. Volume 28, Issue 4. June 2003, pages 359-528. pp 359-360. Clipboard: Severe acute respiratory syndrome (SARS): an old virus jumping into a new host or a new creation? M S Shaila · More Details Fulltext PDF. pp 361-362. Clipboard: Blueprint of a red mould: ...

  16. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 26; Issue 2. The roots of ancient medicine: an historical outline. B V Subbarayappa. Perspectives Volume 26 Issue 2 June 2001 pp 135-143. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/jbsc/026/02/0135-0143. Author Affiliations.

  17. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 31; Issue 5. Cytomixis impairs meiosis and influences reproductive success in Chlorophytum comosum (Thunb) Jacq. – an additional strategy and possible implications. S K Lattoo S Khan S Bamotra A K Dhar. Reviews Volume 31 Issue 5 December 2006 pp 629-637 ...

  18. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 42; Issue 1. Overexpression of hsa-miR-939 follows by NGFR down-regulation and apoptosis reduction. FAHIMEH HOSSEINI AGHDAEI BAHRAM M SOLTANI SADAT DOKANEHIIFARD SEYED JAVAD MOWLA MASOUD SOLEIMANI. Article Volume 42 Issue 1 March 2017 ...

  19. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 31; Issue 1. Issue front cover thumbnail. Volume 31, Issue 1. March 2006, pages 1-176e. pp 1-2. Clipboard: Ancient Indian roots? Denise R Carvalho-Silva Tatiana Zerjal Chris Tyler-Smith · More Details Fulltext PDF. pp 3-4. Commentary: Magic with moulds: Meiotic and ...

  20. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 29; Issue 1. What impact, if any, has feminism had on science? Evelyn Fox Keller. Perspectives Volume 29 Issue 1 March 2004 pp 7-13. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/jbsc/029/01/0007-0013. Author Affiliations.

  1. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... Journals; Journal of Biosciences; Volume 35; Issue 1. Transgene transmission in South American catfish (Rhamdia quelen) larvae by sperm-mediated gene transfer. Tiago Collares Vinicius Farias Campos Fabiana Kömmling Seixas Paulo V Cavalcanti Odir A Dellagostin Heden Luiz M Moreira João Carlos Deschamps.

  2. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2010-11-09

    Nov 9, 2010 ... Home; Journals; Journal of Biosciences; Volume 35; Issue 4. What history tells us XXII. The French neo-Lamarckians. Michel Morange. Series Volume 35 Issue 4 December 2010 pp 515-517. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/jbsc/035/04/0515-0517 ...

  3. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2006-05-06

    May 6, 2006 ... Home; Journals; Journal of Biosciences; Volume 31; Issue 2. Kenneth Raper, Elisha Mitchell and Dictyostelium. Eugene R Katz. Perspectives Volume 31 Issue 2 June 2006 pp 195-200. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/jbsc/031/02/0195-0200 ...

  4. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2008-01-31

    Jan 31, 2008 ... Home; Journals; Journal of Biosciences; Volume 33; Issue 1. Biological time is fractal: Early events reverberate over a life time. David Lloyd. Perspectives Volume 33 Issue 1 March 2008 pp 9-19. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/jbsc/033/01/0009- ...

  5. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Anandasankar Ray1 2 Wynand Van Der Goes Van Naters2 3 John R Carlson2. Department of Entomology, University of California, Riverside, CA 92521, USA; Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06520, USA; School of Biosciences, Cardiff University, Cardiff, UK ...

  6. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2010-02-10

    Feb 10, 2010 ... Home; Journals; Journal of Biosciences; Volume 35; Issue 1. What history tells us XX. Felix Haurowitz (1896–1987) – A difficult journey in the political and scientific upheavals of the 20th century. Michel Morange. Series Volume 35 Issue 1 March 2010 pp 17-20 ...

  7. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2005-11-15

    Nov 15, 2005 ... Home; Journals; Journal of Biosciences; Volume 30; Issue 5. What history tells us III. André Lwoff: From protozoology to molecular definition of viruses. Michel Morange. Series Volume 30 Issue 5 December 2005 pp 591-594. Fulltext. Click here to view fulltext PDF. Permanent link:

  8. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2005-11-23

    Nov 23, 2005 ... Home; Journals; Journal of Biosciences; Volume 30; Issue 5. Commentary: Neuronal survival in epilepsy: to die or not to die? Subramaniam Ganesh Shweta Singh. Volume 30 Issue 5 December 2005 pp 561-566. Fulltext. Click here to view fulltext PDF. Permanent link:

  9. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 34; Issue 6 ... of R. solani (35 colony-forming units/g dry soil) was relatively high in the soil we studied, and ... School of Environment, Resources and Development, Asian Institute of Technology, ...

  10. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... Mid Year Meetings · Discussion Meetings · Public Lectures · Lecture Workshops · Refresher Courses · Symposia · Live Streaming. Home; Journals; Journal of Biosciences; Volume 28; Issue 2. Integrative microbiology – the third Golden Age. Moselio Schaechter. Perspectives Volume 28 Issue 2 March 2003 pp 149-154 ...

  11. Using PubMed search strings for efficient retrieval of manual therapy research literature.

    Science.gov (United States)

    Pillastrini, Paolo; Vanti, Carla; Curti, Stefania; Mattioli, Stefano; Ferrari, Silvano; Violante, Francesco Saverio; Guccione, Andrew

    2015-02-01

    The aim of this study was to construct PubMed search strings that could efficiently retrieve studies on manual therapy (MT), especially for time-constrained clinicians. Our experts chose 11 Medical Subject Heading terms describing MT along with 84 additional potential terms. For each term that was able to retrieve more than 100 abstracts, we systematically extracted a sample of abstracts from which we estimated the proportion of studies potentially relevant to MT. We then constructed 2 search strings: 1 narrow (threshold of pertinent articles ≥40%) and 1 expanded (including all terms for which a proportion had been calculated). We tested these search strings against articles on 2 conditions relevant to MT (thoracic and temporomandibular pain). We calculated the number of abstracts needed to read (NNR) to identify 1 potentially pertinent article in the context of these conditions. Finally, we evaluated the efficiency of the proposed PubMed search strings to identify relevant articles included in a systematic review on spinal manipulative therapy for chronic low back pain. Fifty-five search terms were able to extract more than 100 citations. The NNR to find 1 potentially pertinent article using the narrow string was 1.2 for thoracic pain and 1.3 for temporomandibular pain, and the NNR for the expanded string was 1.9 and 1.6, respectively. The narrow search strategy retrieved all the randomized controlled trials included in the systematic review selected for comparison. The proposed PubMed search strings may help health care professionals locate potentially pertinent articles and review a large number of MT studies efficiently to better implement evidence-based practice. Copyright © 2015 National University of Health Sciences. Published by Elsevier Inc. All rights reserved.

  12. Transportation literature search & synthesis report : research and state DOT practice on construction cost indices.

    Science.gov (United States)

    2012-01-18

    The literature review identifies completed research and other authoritative information in an area of interest. The citations below are representative, rather than exhaustive, of available English-language studies on the topic. Primary online resourc...

  13. Time relevance, citation of reporting guidelines, and breadth of literature search in systematic reviews in orthodontics

    NARCIS (Netherlands)

    Livas, Christos; Pandis, Nikolaos; Ren, Yijin

    Introduction: As the importance of systematic review (SR) conclusions relies upon the scientific rigor of methods and the currency of evidence, we aimed to investigate the currency of orthodontic SRs using as proxy the time from the initial search to publication. Additionally, SR information

  14. Promoting evidence based medicine in preclinical medical students via a federated literature search tool.

    Science.gov (United States)

    Keim, Samuel Mark; Howse, David; Bracke, Paul; Mendoza, Kathryn

    2008-01-01

    Medical educators are increasingly faced with directives to teach Evidence Based Medicine (EBM) skills. Because of its nature, integrating fundamental EBM educational content is a challenge in the preclinical years. To analyse preclinical medical student user satisfaction and feedback regarding a clinical EBM search strategy. The authors introduced a custom EBM search option with a self-contained education structure to first-year medical students. The implementation took advantage of a major curricular change towards case-based instruction. Medical student views and experiences were studied regarding the tool's convenience, problems and the degree to which they used it to answer questions raised by case-based instruction. Surveys were completed by 70% of the available first-year students. Student satisfaction and experiences were strongly positive towards the EBM strategy, especially of the tool's convenience and utility for answering issues raised during case-based learning sessions. About 90% of the students responded that the tool was easy to use, productive and accessed for half or more of their search needs. This study provides evidence that the integration of an educational EBM search tool can be positively received by preclinical medical students.

  15. Literature search on the use of resins for treatment of radioactive wastes

    International Nuclear Information System (INIS)

    AlMahamid, I.; Smith, B.M.

    1997-10-01

    Over 100 commercial providers with mixed-waste treatability capabilities exist in the US. The maturity level of these technologies varies from a bench scale to a pilot or a commercial scale. The techniques include deactivation, chemical oxidation, recovery of metals, stabilization, vitrification, incineration, biodegradation, and chemical extraction. This report focuses on the use of resins to remove actinides and heavy metals from aqueous waste streams. Only the literature that described resins with high removing efficiency are presented here. The majority of the literature reviewed are proceedings and national or international reports ordered through the Berkeley Lab Library. Some of the reports that the authors requested have not yet arrived. Only a few papers were found in the open literature (journals or magazines). Although this report does not include all existing references, it provides an accurate assessment of efficient resins to be considered for waste minimization procedures. 70 refs

  16. Environmental Biosciences Program Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2009-01-30

    Current research projects have focused Environmental Biosciences Program (EBP) talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene, low-dose ionizing radiation (gamma and neutron) and alpha radiation from plutonium. Trichloroethylene research has been conducted as a joint collaborative effort with the University of Georgia. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the United States Department of Energy (DOE). Laboratory work has been completed on several trichloroethylene risk assessment projects, and these projects have been brought to a close. Plans for restructuring the performance schedule of the remaining trichloroethylene projects have been submitted to the department. A comprehensive manuscript on the scientific basis of trichloroethylene risk assessment is in preparation. Work on the low-dose radiation risk assessment projects is also progressing at a slowed rate as a result of funding uncertainties. It has been necessary to restructure the proponency and performance schedule of these projects, with the project on Low-Dose Radiation: Epidemiology Risk Models transferred to DOE Office of Science proponency under a separate funding instrument. Research on this project will continue under the provisions of the DOE Office of Science funding instrument, with progress reported in accordance with the requirements of that funding instrument. Progress on that project will no longer be reported in quarterly reports for DE-FC09-02CH11109. Following a meeting at the Savannah River Site on May 8, 2008, a plan was submitted for development of an epidemiological cohort study and prospective medical surveillance system for the assessment of disease rates among workers at the Savannah River

  17. Searching for a Common Ground--A Literature Review of Empirical Research on Scientific Inquiry Activities

    Science.gov (United States)

    Rönnebeck, Silke; Bernholt, Sascha; Ropohl, Mathias

    2016-01-01

    Despite the importance of scientific inquiry in science education, researchers and educators disagree considerably regarding what features define this instructional approach. While a large body of literature addresses theoretical considerations, numerous empirical studies investigate scientific inquiry on quite different levels of detail and also…

  18. In Search of Cultural Diversity: Recent Literature in Cross-Cultural and Ethnic Minority Psychology.

    Science.gov (United States)

    Hall, Gordon C. Nagayama; Maramba, Gloria Gia

    2001-01-01

    Identifies where most work on cross-cultural and ethnic minority psychology is being published and the authors. Very little overlap was found between literature in cross-cultural and ethnic minority psychology. Top scholars in cross-cultural psychology are men of European ancestry, while in ethnic minority psychology, scholars are ethnic…

  19. Object-oriented programming for the biosciences.

    Science.gov (United States)

    Wiechert, W; Joksch, B; Wittig, R; Hartbrich, A; Höner, T; Möllney, M

    1995-10-01

    The development of software systems for the biosciences is always closely connected to experimental practice. Programs must be able to handle the inherent complexity and heterogeneous structure of biological systems in combination with the measuring equipment. Moreover, a high degree of flexibility is required to treat rapidly changing experimental conditions. Object-oriented methodology seems to be well suited for this purpose. It enables an evolutionary approach to software development that still maintains a high degree of modularity. This paper presents experience with object-oriented technology gathered during several years of programming in the fields of bioprocess development and metabolic engineering. It concentrates on the aspects of experimental support, data analysis, interaction and visualization. Several examples are presented and discussed in the general context of the experimental cycle of knowledge acquisition, thus pointing out the benefits and problems of object-oriented technology in the specific application field of the biosciences. Finally, some strategies for future development are described.

  20. Some of the factors influencing the Heel Pad Compressibility Index (HPCI): a literature search

    DEFF Research Database (Denmark)

    Matteoli, Sara; Wilhjelm, Jens E.; Torp-Pedersen, Soren T.

    2009-01-01

    The human heel pad is a complex structure that features non-linear visco-elastic characteristics as the majority of the human soft tissues. The biomechanical aspects of the heel pad are still under investigation and the influence of subject factors such as age, weight, gender, height, race......, and body activity have been reported. The aim of this paper is to study the literature in order to identify the influence of subject factors and diseases on the heel pad compressibility index....

  1. Applying systematic review search methods to the grey literature: a case study examining guidelines for school-based breakfast programs in Canada.

    Science.gov (United States)

    Godin, Katelyn; Stapleton, Jackie; Kirkpatrick, Sharon I; Hanning, Rhona M; Leatherdale, Scott T

    2015-10-22

    Grey literature is an important source of information for large-scale review syntheses. However, there are many characteristics of grey literature that make it difficult to search systematically. Further, there is no 'gold standard' for rigorous systematic grey literature search methods and few resources on how to conduct this type of search. This paper describes systematic review search methods that were developed and applied to complete a case study systematic review of grey literature that examined guidelines for school-based breakfast programs in Canada. A grey literature search plan was developed to incorporate four different searching strategies: (1) grey literature databases, (2) customized Google search engines, (3) targeted websites, and (4) consultation with contact experts. These complementary strategies were used to minimize the risk of omitting relevant sources. Since abstracts are often unavailable in grey literature documents, items' abstracts, executive summaries, or table of contents (whichever was available) were screened. Screening of publications' full-text followed. Data were extracted on the organization, year published, who they were developed by, intended audience, goal/objectives of document, sources of evidence/resources cited, meals mentioned in the guidelines, and recommendations for program delivery. The search strategies for identifying and screening publications for inclusion in the case study review was found to be manageable, comprehensive, and intuitive when applied in practice. The four search strategies of the grey literature search plan yielded 302 potentially relevant items for screening. Following the screening process, 15 publications that met all eligibility criteria remained and were included in the case study systematic review. The high-level findings of the case study systematic review are briefly described. This article demonstrated a feasible and seemingly robust method for applying systematic search strategies to

  2. Preliminary comparison of the Essie and PubMed search engines for answering clinical questions using MD on Tap, a PDA-based program for accessing biomedical literature.

    Science.gov (United States)

    Sutton, Victoria R; Hauser, Susan E

    2005-01-01

    MD on Tap, a PDA application that searches and retrieves biomedical literature, is specifically designed for use by mobile healthcare professionals. With the goal of improving the usability of the application, a preliminary comparison was made of two search engines (PubMed and Essie) to determine which provided most efficient path to the desired clinically-relevant information.

  3. Developing Research Capabilities in Energy Biosciences

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Donald D.

    2008-01-01

    Scientists founded the Life Sciences Research Foundation (LSRF) in 1983 as a non-profit pass through foundation that awards post doctoral fellowships in all areas of the life sciences. LSRF scientists review hundreds of applications each year from PhDs seeking support. For example this year, our 26th, we received 800 applications and our peer review committee will choose about 50 finalists who are eligible for these awards. We have no endowment so we solicit sponsors each year. The fellowships are sponsored by research oriented companies, foundations, philanthropists, the Howard Hughes Medical Institute, and other organizations who believe in the value of awarding fellowships to the best and the brightest young scientists. Our web site has a complete listing of all details about LSRF (http://www.lsrf.org/). In the late 1980s the Division of Bioscience in the Office of Basic Energy Science, a granting agency of the Department of Energy, joined this partnership. Bioscience's mandate was to support non-medical microbiology and plant sciences. LSRF received a series of 5 year grants from DOE to award fellowships to our top applicants in these fields of research. We began to support DOE-Energy Bioscience post doctoral fellows in 1989. From 1989 through 2004 when DOE funding ended our partnership awarded 41 DOE-Energy Bioscience Fellows of the Life Sciences Research Foundation. Each of these was a three year fellowship. DOE-Energy Biosciences was well matched with LSRF. Our extensive peer review screened applicants in all areas of the life sciences. Most LSRF sponsors are interested in supporting fellows who work on diseases. At the time that we began our partnership with DOE we had no sponsors willing to support plant biology and non medical microbiology. For 15 years DOE played a major role in the training of the very best young scientists in these important fields of research simply through its support of LSRF post doctoral fellows. Young scientists interested in

  4. Ancient Glass: A Literature Search and its Role in Waste Management

    International Nuclear Information System (INIS)

    Strachan, Denis M.; Pierce, Eric M.

    2010-01-01

    When developing a performance assessment model for the long-term disposal of immobilized low-activity waste (ILAW) glass, it is desirable to determine the durability of glass forms over very long periods of time. However, testing is limited to short time spans, so experiments are performed under conditions that accelerate the key geochemical processes that control weathering. Verification that models currently being used can reliably calculate the long term behavior ILAW glass is a key component of the overall PA strategy. Therefore, Pacific Northwest National Laboratory was contracted by Washington River Protection Solutions, LLC to evaluate alternative strategies that can be used for PA source term model validation. One viable alternative strategy is the use of independent experimental data from archaeological studies of ancient or natural glass contained in the literature. These results represent a potential independent experiment that date back to approximately 3600 years ago or 1600 before the current era (bce) in the case of ancient glass and 106 years or older in the case of natural glass. The results of this literature review suggest that additional experimental data may be needed before the result from archaeological studies can be used as a tool for model validation of glass weathering and more specifically disposal facility performance. This is largely because none of the existing data set contains all of the information required to conduct PA source term calculations. For example, in many cases the sediments surrounding the glass was not collected and analyzed; therefore having the data required to compare computer simulations of concentration flux is not possible. This type of information is important to understanding the element release profile from the glass to the surrounding environment and provides a metric that can be used to calibrate source term models. Although useful, the available literature sources do not contain the required information

  5. Ancient Glass: A Literature Search and its Role in Waste Management

    Energy Technology Data Exchange (ETDEWEB)

    Strachan, Denis M.; Pierce, Eric M.

    2010-07-01

    When developing a performance assessment model for the long-term disposal of immobilized low-activity waste (ILAW) glass, it is desirable to determine the durability of glass forms over very long periods of time. However, testing is limited to short time spans, so experiments are performed under conditions that accelerate the key geochemical processes that control weathering. Verification that models currently being used can reliably calculate the long term behavior ILAW glass is a key component of the overall PA strategy. Therefore, Pacific Northwest National Laboratory was contracted by Washington River Protection Solutions, LLC to evaluate alternative strategies that can be used for PA source term model validation. One viable alternative strategy is the use of independent experimental data from archaeological studies of ancient or natural glass contained in the literature. These results represent a potential independent experiment that date back to approximately 3600 years ago or 1600 before the current era (bce) in the case of ancient glass and 106 years or older in the case of natural glass. The results of this literature review suggest that additional experimental data may be needed before the result from archaeological studies can be used as a tool for model validation of glass weathering and more specifically disposal facility performance. This is largely because none of the existing data set contains all of the information required to conduct PA source term calculations. For example, in many cases the sediments surrounding the glass was not collected and analyzed; therefore having the data required to compare computer simulations of concentration flux is not possible. This type of information is important to understanding the element release profile from the glass to the surrounding environment and provides a metric that can be used to calibrate source term models. Although useful, the available literature sources do not contain the required information

  6. Multimedia Interactive eBooks in Laboratory Bioscience Education

    Science.gov (United States)

    Morris, Neil P.; Lambe, James

    2017-01-01

    Bioscience students in the UK higher education system are making increasing use of technology to support their learning within taught classes and during private study. This experimental study was designed to assess the role for multimedia interactive eBooks in bioscience laboratory classes, delivered using a blended learning approach. Thirty-nine…

  7. Compliance of systematic reviews in veterinary journals with Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) literature search reporting guidelines.

    Science.gov (United States)

    Toews, Lorraine C

    2017-07-01

    Complete, accurate reporting of systematic reviews facilitates assessment of how well reviews have been conducted. The primary objective of this study was to examine compliance of systematic reviews in veterinary journals with Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines for literature search reporting and to examine the completeness, bias, and reproducibility of the searches in these reviews from what was reported. The second objective was to examine reporting of the credentials and contributions of those involved in the search process. A sample of systematic reviews or meta-analyses published in veterinary journals between 2011 and 2015 was obtained by searching PubMed. Reporting in the full text of each review was checked against certain PRISMA checklist items. Over one-third of reviews (37%) did not search the CAB Abstracts database, and 9% of reviews searched only 1 database. Over two-thirds of reviews (65%) did not report any search for grey literature or stated that they excluded grey literature. The majority of reviews (95%) did not report a reproducible search strategy. Most reviews had significant deficiencies in reporting the search process that raise questions about how these searches were conducted and ultimately cast serious doubts on the validity and reliability of reviews based on a potentially biased and incomplete body of literature. These deficiencies also highlight the need for veterinary journal editors and publishers to be more rigorous in requiring adherence to PRISMA guidelines and to encourage veterinary researchers to include librarians or information specialists on systematic review teams to improve the quality and reporting of searches.

  8. Searching the seat of the soul in Ancient Greek and Byzantine medical literature.

    Science.gov (United States)

    Lykouras, Eleftherios; Poulakou-Rebelakou, Effie; Ploumpidis, Demetrios N

    2010-12-01

    The objective of this paper was to examine the ancient and medieval concepts about the seat of the mental functions, as exposed in Greek texts from Antiquity to Byzantine times. The review of the philosophical and medical literature from the original ancient Greek language from the Homeric epics to the Holy Fathers of Christianity, as the problem of the seat of the soul remained without a certain answer through the centuries. Primitive concepts attributed great significance to the soul and dictated cannibal behaviours for the possession and eating of the defeated enemy's heart. Mental functions, such as thinking, feeling and mainly those related to affective manifestations, were attributed to the heart and to some other internal organs (liver, diaphragm) from the times of Greek mythology. Philosophy and empirical medicine had underestimated the brain probably because it is a 'silent' organ, contrary to the palpitating heart, with its obvious participations in the emotional reactions. The role of the brain as the mental organ and the seat of emotions has been gradually recognized. The permanent question of the seat of the soul had been for many centuries a critical dispute and the contribution of Greek philosophical and medical thought was decisive for the contemporary transformation of the whole concept.

  9. Spatial analysis for the epidemiological study of cardiovascular diseases: A systematic literature search.

    Science.gov (United States)

    Mena, Carlos; Sepúlveda, Cesar; Fuentes, Eduardo; Ormazábal, Yony; Palomo, Iván

    2018-05-07

    Cardiovascular diseases (CVDs) are the primary cause of death and disability in de world, and the detection of populations at risk as well as localization of vulnerable areas is essential for adequate epidemiological management. Techniques developed for spatial analysis, among them geographical information systems and spatial statistics, such as cluster detection and spatial correlation, are useful for the study of the distribution of the CVDs. These techniques, enabling recognition of events at different geographical levels of study (e.g., rural, deprived neighbourhoods, etc.), make it possible to relate CVDs to factors present in the immediate environment. The systemic literature presented here shows that this group of diseases is clustered with regard to incidence, mortality and hospitalization as well as obesity, smoking, increased glycated haemoglobin levels, hypertension physical activity and age. In addition, acquired variables such as income, residency (rural or urban) and education, contribute to CVD clustering. Both local cluster detection and spatial regression techniques give statistical weight to the findings providing valuable information that can influence response mechanisms in the health services by indicating locations in need of intervention and assignment of available resources.

  10. Introducing bioinformatics, the biosciences' genomic revolution

    CERN Document Server

    Zanella, Paolo

    1999-01-01

    The general audience for these lectures is mainly physicists, computer scientists, engineers or the general public wanting to know more about what’s going on in the biosciences. What’s bioinformatics and why is all this fuss being made about it ? What’s this revolution triggered by the human genome project ? Are there any results yet ? What are the problems ? What new avenues of research have been opened up ? What about the technology ? These new developments will be compared with what happened at CERN earlier in its evolution, and it is hoped that the similiraties and contrasts will stimulate new curiosity and provoke new thoughts.

  11. Buccals tablets - literature search

    OpenAIRE

    Horáček, Jan

    2007-01-01

    BUCCAL TABLETS Jan Horáček ABSTRACT My diploma thesis was aimed at summarising information about phenomena of bioadhesion in connection with administration of drugs. The work describes anatomy and physiology of oral mucosa and differencies in various parts of oral cavity. It refers about advantages and limits of administrating drugs through the oral mucosa. The part called Bioadhesion / mucoadhesion includes definition, theories, influencing factors and description of methods to determinate b...

  12. Building and evaluating an informatics tool to facilitate analysis of a biomedical literature search service in an academic medical center library.

    Science.gov (United States)

    Hinton, Elizabeth G; Oelschlegel, Sandra; Vaughn, Cynthia J; Lindsay, J Michael; Hurst, Sachiko M; Earl, Martha

    2013-01-01

    This study utilizes an informatics tool to analyze a robust literature search service in an academic medical center library. Structured interviews with librarians were conducted focusing on the benefits of such a tool, expectations for performance, and visual layout preferences. The resulting application utilizes Microsoft SQL Server and .Net Framework 3.5 technologies, allowing for the use of a web interface. Customer tables and MeSH terms are included. The National Library of Medicine MeSH database and entry terms for each heading are incorporated, resulting in functionality similar to searching the MeSH database through PubMed. Data reports will facilitate analysis of the search service.

  13. Temporary shelter-in-place as protection against a release of airborne hazardous material : report of a literature search.; TOPICAL

    International Nuclear Information System (INIS)

    Yantosik, G. D.; Lerner, K.; Maloney, D. M.

    2002-01-01

    ''Temporary shelter-in place'' is the combination of prompt shelter-in-place (SIP) to minimize initial exposure to airborne hazardous material, followed by timely action to terminate this protection to minimize exposure to hazardous vapor accumulations in the shelter once the air outside becomes less hazardous than the air inside the shelter. Temporary SIP, if properly executed, is considered to be an effective way to protect populations from hazardous chemical vapors, especially from high concentrations for short periods. This is supported by laboratory and field experiments. The need for timely termination of temporary SIP as protection from infiltrated vapors is an integral component of a temporary SIP strategy. It was from this premise that Argonne National Laboratory (ANL) was asked to develop methodologies for deciding when and how to terminate SIP. These methodologies, in turn, could be the basis for site-specific operational guidelines (e.g., decision matrix, decision-tree, or algorithm) for terminating SIP on each of the eight Army chemical stockpile storage sites, and in the off-post communities surrounding them. This project consists of two tasks. Task 1 was to collect and analyze existing literature that might be relevant to the termination of temporary SIP. This report is the product of Task 1. Task 2, which will begin on 2 February 2001, will use the results of the literature search as the baseline to investigate the concepts associated with temporary SIP, and to develop methodologies for termination of temporary SIP that can be incorporated in site-specific operational guidelines. It is understood that these methods will be consistent with Chemical Stockpile Emergency Preparedness Program (CSEPP) policy that ''the most important objective of the emergency preparedness and implementation process is the avoidance of fatalities to the maximum extent practicable, should an accidental release of chemical agent occur.'' It is also anticipated that these

  14. Approaches to Recruiting 'Hard-To-Reach' Populations into Re-search: A Review of the Literature.

    Science.gov (United States)

    Shaghaghi, Abdolreza; Bhopal, Raj S; Sheikh, Aziz

    2011-01-01

    'Hard-to-reach' is a term used to describe those sub-groups of the population that may be difficult to reach or involve in research or public health programmes. Application of a single term to call these sub-sections of populations implies a homogeneity within distinct groups, which does not necessarily exist. Different sampling techniques were introduced so far to recruit hard-to-reach populations. In this article, we have reviewed a range of ap-proaches that have been used to widen participation in studies. We performed a Pubmed and Google search for relevant English language articles using the keywords and phrases: (hard-to-reach AND population* OR sampl*), (hidden AND population* OR sample*) and ("hard to reach" AND population* OR sample*) and a consul-tation of the retrieved articles' bibliographies to extract empirical evidence from publications that discussed or examined the use of sampling techniques to recruit hidden or hard-to-reach populations in health studies. Reviewing the literature has identified a range of techniques to recruit hard-to-reach populations, including snowball sampling, respondent-driven sampling (RDS), indigenous field worker sampling (IFWS), facility-based sampling (FBS), targeted sampling (TS), time-location (space) sampling (TLS), conventional cluster sampling (CCS) and capture re-capture sampling (CR). The degree of compliance with a study by a certain 'hard-to-reach' group de-pends on the characteristics of that group, recruitment technique used and the subject of inter-est. Irrespective of potential advantages or limitations of the recruitment techniques reviewed, their successful use depends mainly upon our knowledge about specific characteristics of the target populations. Thus in line with attempts to expand the current boundaries of our know-ledge about recruitment techniques in health studies and their applications in varying situa-tions, we should also focus on possibly all contributing factors which may have an impact on

  15. Approaches to Recruiting ‘Hard-To-Reach’ Populations into Re­search: A Review of the Literature

    Directory of Open Access Journals (Sweden)

    Aziz Sheikh

    2011-12-01

    Full Text Available Background: ‘Hard-to-reach’ is a term used to describe those sub-groups of the populationthat may be difficult to reach or involve in research or public health programmes. Applicationof a single term to call these sub-sections of populations implies a homogeneity within distinctgroups, which does not necessarily exist. Different sampling techniques were introduced sofar to recruit hard-to-reach populations. In this article, we have reviewed a range of approachesthat have been used to widen participation in studies.Methods: We performed a Pubmed and Google search for relevant English language articlesusing the keywords and phrases: (hard-to-reach AND population* OR sampl*, (hidden ANDpopulation* OR sample* and (“hard to reach” AND population* OR sample* and a consultationof the retrieved articles’ bibliographies to extract empirical evidence from publicationsthat discussed or examined the use of sampling techniques to recruit hidden or hard-to-reachpopulations in health studies.Results: Reviewing the literature has identified a range of techniques to recruit hard-to-reachpopulations, including snowball sampling, respondent-driven sampling (RDS, indigenousfield worker sampling (IFWS, facility-based sampling (FBS, targeted sampling (TS, timelocation(space sampling (TLS, conventional cluster sampling (CCS and capture re-capturesampling (CR.Conclusion: The degree of compliance with a study by a certain ‘hard-to-reach’ group dependson the characteristics of that group, recruitment technique used and the subject of interest.Irrespective of potential advantages or limitations of the recruitment techniques reviewed,their successful use depends mainly upon our knowledge about specific characteristics of thetarget populations. Thus in line with attempts to expand the current boundaries of our knowledgeabout recruitment techniques in health studies and their applications in varying situations,we should also focus on possibly all contributing

  16. Assessing the performance of methodological search filters to improve the efficiency of evidence information retrieval: five literature reviews and a qualitative study.

    Science.gov (United States)

    Lefebvre, Carol; Glanville, Julie; Beale, Sophie; Boachie, Charles; Duffy, Steven; Fraser, Cynthia; Harbour, Jenny; McCool, Rachael; Smith, Lynne

    2017-11-01

    Effective study identification is essential for conducting health research, developing clinical guidance and health policy and supporting health-care decision-making. Methodological search filters (combinations of search terms to capture a specific study design) can assist in searching to achieve this. This project investigated the methods used to assess the performance of methodological search filters, the information that searchers require when choosing search filters and how that information could be better provided. Five literature reviews were undertaken in 2010/11: search filter development and testing; comparison of search filters; decision-making in choosing search filters; diagnostic test accuracy (DTA) study methods; and decision-making in choosing diagnostic tests. We conducted interviews and a questionnaire with experienced searchers to learn what information assists in the choice of search filters and how filters are used. These investigations informed the development of various approaches to gathering and reporting search filter performance data. We acknowledge that there has been a regrettable delay between carrying out the project, including the searches, and the publication of this report, because of serious illness of the principal investigator. The development of filters most frequently involved using a reference standard derived from hand-searching journals. Most filters were validated internally only. Reporting of methods was generally poor. Sensitivity, precision and specificity were the most commonly reported performance measures and were presented in tables. Aspects of DTA study methods are applicable to search filters, particularly in the development of the reference standard. There is limited evidence on how clinicians choose between diagnostic tests. No published literature was found on how searchers select filters. Interviewing and questioning searchers via a questionnaire found that filters were not appropriate for all tasks but were

  17. Measuring children’s distress during burns dressing changes: literature search for measures appropriate for indigenous children in South Africa

    Directory of Open Access Journals (Sweden)

    Louw QA

    2011-09-01

    Full Text Available Quinette Louw1,2, Karen Grimmer-Somers2, Angie Schrikk31Department of Physiotherapy, Stellenbosch University, Cape Town, South Africa; 2International Centre for Allied Health Evidence, University of South Australia, Adelaide, South Australia, Australia; 3Red Cross Children’s Hospital, Cape Town, South AfricaBackground: Virtual reality is consistently reported as effective in reducing pain and anxiety in children during burns dressing changes in recent Western studies. Pain scales are a commonly reported outcome measure. Virtual reality is persuasive for all children in distress during medical procedures, because it is a nonaddictive, novel, and inexpensive form of distraction which can be applied repeatedly with good effect. We intend to use virtual reality in South Africa for the many children hospitalized with severe burns from mechanisms rarely seen in the Western world (paraffin/kerosene stoves exploding, electrical fires, shack/township fires, boiling liquid spills. Many severely burnt children are indigenous South Africans who did not speak English, and whose illiteracy levels, cultures, family dynamics, and experiences of pain potentially invalidate the use of conventional pain scales as outcome measures. The purpose of this study was to identify objective measures with sound psychometric properties and strong clinical utility, to assess distress during burns dressing changes in hospitalized indigenous South African children. Choice of measures was constrained by the burns dressing change environment, the ethics of doing no harm whilst measuring distress in vulnerable children, and of capturing valid measures of distress over the entire burns dressing change procedure.Methods: We conducted two targeted systematic reviews of the literature. All major library databases were searched, and measures with strong psychometric properties and sound clinical utility were sought.Results: Seven potentially useful measures were identified, ie

  18. Approaches to Recruiting ‘Hard-To-Reach’ Populations into Re­search: A Review of the Literature

    Science.gov (United States)

    Shaghaghi, Abdolreza; Bhopal, Raj S; Sheikh, Aziz

    2011-01-01

    Background: ‘Hard-to-reach’ is a term used to describe those sub-groups of the population that may be difficult to reach or involve in research or public health programmes. Application of a single term to call these sub-sections of populations implies a homogeneity within distinct groups, which does not necessarily exist. Different sampling techniques were introduced so far to recruit hard-to-reach populations. In this article, we have reviewed a range of ap­proaches that have been used to widen participation in studies. Methods: We performed a Pubmed and Google search for relevant English language articles using the keywords and phrases: (hard-to-reach AND population* OR sampl*), (hidden AND population* OR sample*) and (“hard to reach” AND population* OR sample*) and a consul­tation of the retrieved articles’ bibliographies to extract empirical evidence from publications that discussed or examined the use of sampling techniques to recruit hidden or hard-to-reach populations in health studies. Results: Reviewing the literature has identified a range of techniques to recruit hard-to-reach populations, including snowball sampling, respondent-driven sampling (RDS), indigenous field worker sampling (IFWS), facility-based sampling (FBS), targeted sampling (TS), time-location (space) sampling (TLS), conventional cluster sampling (CCS) and capture re-capture sampling (CR). Conclusion: The degree of compliance with a study by a certain ‘hard-to-reach’ group de­pends on the characteristics of that group, recruitment technique used and the subject of inter­est. Irrespective of potential advantages or limitations of the recruitment techniques reviewed, their successful use depends mainly upon our knowledge about specific characteristics of the target populations. Thus in line with attempts to expand the current boundaries of our know­ledge about recruitment techniques in health studies and their applications in varying situa­tions, we should also focus on

  19. What methods do reviews of normative ethics literature use for search, selection, analysis, and synthesis? In-depth results from a systematic review of reviews.

    Science.gov (United States)

    Mertz, Marcel; Strech, Daniel; Kahrass, Hannes

    2017-12-19

    (Semi-)systematic approaches to finding, analysing, and synthesising ethics literature on medical topics are still in their infancy. However, our recent systematic review showed that the rate of publication of such (semi-)systematic reviews has increased in the last two decades. This is not only true for reviews of empirical ethics literature, but also for reviews of normative ethics literature. In the latter case, there is currently little in the way of standards and guidance available. Therefore, the methods and reporting strategies of such reviews vary greatly. The purpose of the follow-up study we present was to obtain deeper methodological insight into the ways reviews of normative literature are actually conducted and to analyse the methods used. Our search in the PubMed, PhilPapers, and Google Scholar databases led to the identification of 183 reviews of ethics literature published between 1997 and 2015, of which 84 were identified as reviews of normative and mixed literature. Qualitative content analysis was used to extract and synthesise descriptions of search, selection, quality appraisal, analysis, and synthesis methods. We further assessed quantitatively how often certain methods (e.g. search strategies, data analysis procedures) were used by the reviews. The overall reporting quality varies among the analysed reviews and was generally poor even for major criteria regarding the search and selection of literature. For example, only 24 (29%) used a PRISMA flowchart. Also, only 55 (66%) reviews mentioned the information unit they sought to extract, and 12 (14%) stated an ethical approach as the theoretical basis for the analysis. Interpretable information on the synthesis method was given by 47 (60%); the most common methods applied were qualitative methods commonly used in social science research (83%). Reviews which fail to provide sufficient relevant information to readers have reduced methodological transparency regardless of actual methodological

  20. Testing of the OMERACT 8 draft validation criteria for a soluble biomarker reflecting structural damage in rheumatoid arthritis: a systematic literature search on 5 candidate biomarkers

    DEFF Research Database (Denmark)

    Syversen, Silje W; Landewe, Robert; van der Heijde, Désirée

    2009-01-01

    OBJECTIVE: To test the OMERACT 8 draft validation criteria for soluble biomarkers by assessing the strength of literature evidence in support of 5 candidate biomarkers. METHODS: A systematic literature search was conducted on the 5 soluble biomarkers RANKL, osteoprotegerin (OPG), matrix...... metalloprotease (MMP-3), urine C-telopeptide of types I and II collagen (U-CTX-I and U CTX-II), focusing on the 14 OMERACT 8 criteria. Two electronic voting exercises were conducted to address: (1) strength of evidence for each biomarker as reflecting structural damage according to each individual criterion...

  1. The (Mathematical) Modeling Process in Biosciences.

    Science.gov (United States)

    Torres, Nestor V; Santos, Guido

    2015-01-01

    In this communication, we introduce a general framework and discussion on the role of models and the modeling process in the field of biosciences. The objective is to sum up the common procedures during the formalization and analysis of a biological problem from the perspective of Systems Biology, which approaches the study of biological systems as a whole. We begin by presenting the definitions of (biological) system and model. Particular attention is given to the meaning of mathematical model within the context of biology. Then, we present the process of modeling and analysis of biological systems. Three stages are described in detail: conceptualization of the biological system into a model, mathematical formalization of the previous conceptual model and optimization and system management derived from the analysis of the mathematical model. All along this work the main features and shortcomings of the process are analyzed and a set of rules that could help in the task of modeling any biological system are presented. Special regard is given to the formative requirements and the interdisciplinary nature of this approach. We conclude with some general considerations on the challenges that modeling is posing to current biology.

  2. Advanced NMR technology for bioscience and biotechnology

    Energy Technology Data Exchange (ETDEWEB)

    Hammel, P.C.; Hernandez, G.; Trewhella, J.; Unkefer, C.J. [Los Alamos National Lab., NM (US); Boumenthal, D.K. [Univ. of Utah, Salt Lake City, UT (US); Kennedy, M.A. [Pacific Northwest National Lab., Richland, WA (US); Moore, G.J. [Wayne State Univ., Detroit, MI (US)

    1998-11-01

    This is the final report of a three-year, Laboratory Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). NMR plays critical roles in bioscience and biotechnology in both imaging and structure determination. NMR is limited, however, by the inherent low sensitivity of the NMR experiment and the demands for spectral resolution required to study biomolecules. The authors addressed both of these issues by working on the development of NMR force microscopy for molecular imaging, and high field NMR with isotope labeling to overcome limitations in the size of biomolecules that can be studied using NMR. A novel rf coil design for NMR force microscopy was developed that increases the limits of sensitivity in magnetic resonance detection for imaging, and the authors demonstrated sub-surface spatial imaging capabilities. The authors also made advances in the miniaturization of two critical NMR force microscope components. They completed high field NMR and isotope labeling studies of a muscle protein complex which is responsible for regulating muscle contraction and is too large for study using conventional NMR approaches.

  3. Conference scene: Select Biosciences Epigenetics Europe 2010.

    Science.gov (United States)

    Razvi, Enal S

    2011-02-01

    The field of epigenetics is now on a geometric rise, driven in a large part by the realization that modifiers of chromatin are key regulators of biological processes in vivo. The three major classes of epigenetic effectors are DNA methylation, histone post-translational modifications (such as acetylation, methylation or phosphorylation) and small noncoding RNAs (most notably microRNAs). In this article, I report from Select Biosciences Epigenetics Europe 2010 industry conference held on 14-15 September 2010 at The Burlington Hotel, Dublin, Ireland. This industry conference was extremely well attended with a global pool of delegates representing the academic research community, biotechnology companies and pharmaceutical companies, as well as the technology/tool developers. This conference represented the current state of the epigenetics community with cancer/oncology as a key driver. In fact, it has been estimated that approximately 45% of epigenetic researchers today identify cancer/oncology as their main area of focus vis-à-vis their epigenetic research efforts.

  4. Environmental Biosciences Quarterly Report, September - December, 2005

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2006-01-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  5. Environmental Biosciences Program Report for Year Three

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2006-07-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  6. Environmental Biosciences Program Report for Year 2

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2005-10-15

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  7. Environmental Biosciences Program Third Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2003-01-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific program, employing a range of research initiatives to identify, study and resolve environmental health risk issues. These initiatives are consistent with the Medical University's role as a comprehensive state-supported health sciences institution and the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable the Medical University to be a national resource for the scientific investigation of environmental health issues. EBP's success in convening worldwide scientific expertise is due in part to the inherent credibility the Medical University brings to the process of addressing these complex issues.

  8. Environmental Biosciences Program Fourth Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.d.

    2003-04-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific program, employing a range of research initiatives to identify, study and resolve environmental health risk issues. These initiatives are consistent with the Medical University's role as a comprehensive state-supported health sciences institution and the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable the Medical University to be a national resource for the scientific investigation of environmental health issues. EBP's success in convening worldwide scientific expertise is due in part to the inherent credibility the Medical University brings to the process of addressing these complex issues.

  9. Environmental Biosciences Program Second Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2003-12-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), asbestos and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  10. Second Quarter Report Environmental Biosciences Program

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2002-10-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific program, employing a range of research initiatives to identify, study and resolve environmental health risk issues. These initiatives are consistent with the Medical University's role as a comprehensive state-supported health sciences institution and the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable the Medical University to be a national resource for the scientific investigation of environmental health issues. EBP's success in convening worldwide scientific expertise is due in part to the inherent credibility the Medical University brings to the process of addressing these complex issues.

  11. Environmental Biosciences Program Fourth Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2004-06-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), asbestos and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  12. Environmental Biosciences Program Third Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2004-03-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), asbestos and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  13. Environmental Biosciences Program Report for Year 3

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2007-04-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the DOE. Plans for restructuring the performance schedule of the trichloroethylene projects have been submitted to the department. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this

  14. Environmental Biosciences Program Fourth Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2005-06-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation s need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyles (PCBs), and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this cooperative agreement can be forwarded to Dr. Lawrence C. Mohr in the EBP office of the Medical University of South Carolina at (843) 792-1532.

  15. Environmental Biosciences Program Second Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2004-12-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this cooperative agreement can be forwarded to Dr. Lawrence C. Mohr in the EBP office of the Medical University of South Carolina at (843) 792-1532.

  16. Environmental Biosciences Report for Year 3

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2007-10-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the DOE. Plans for restructuring the performance schedule of the trichloroethylene projects have been submitted to the department. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk based decision-making. Questions, comments or requests for further information concerning the activities under this

  17. BredeQuery: Coordinate-Based Meta-analytic Search of Neuroscientific Literature from the SPM Environment

    DEFF Research Database (Denmark)

    Wilkowski, Bartlomiej; Szewczyk, Marcin Marek; Rasmussen, Peter Mondrup

    2010-01-01

    Query offers a direct link from SPM to the Brede Database coordinate-based search engine. BredeQuery is able to ‘grab’ brain location coordinates from the SPM windows and enter them as a query for the Brede Database. Moreover, results of the query can be displayed in a MATLAB window and/or exported directly...

  18. Erratum Journal of Biosciences Volume 34, Number 2, November ...

    Indian Academy of Sciences (India)

    Prakash

    (1) Page 709, Introduction, 4th line from top: 3500 m to be read as 500 m. (2) Page 710, Figure 2 caption, line 1: 3500 m to be read as 500 m. The above corrections require to be made in the printed version of the article. The article that appear on the Journal of. Biosciences Web site will contain these corrections.

  19. Challenges in Understanding Photosynthesis in a University Introductory Biosciences Class

    Science.gov (United States)

    Södervik, Ilona; Virtanen, Viivi; Mikkilä-Erdmann, Mirjamaija

    2015-01-01

    University students' understanding of photosynthesis was examined in a large introductory biosciences class. The focus of this study was to first examine the conceptions of photosynthesis among students in class and then to investigate how a certain type of text could enhance students' understanding of photosynthesis. The study was based on pre-…

  20. Integrating anticipated nutrigenomics bioscience applications with ethical aspects

    NARCIS (Netherlands)

    Levesque, L.; Ozdemir, V.; Gremmen, B.; Godard, B.

    2008-01-01

    Nutrigenomics is a subspecialty of nutrition science which aims to understand how gene-diet interactions influence individuals' response to food, disease susceptibility, and population health. Yet ethical enquiry into this field is being outpaced by nutrigenomics bioscience. The ethical issues

  1. Guidelines for Biomarker of Food Intake Reviews (BFIRev): how to conduct an extensive literature search for biomarker of food intake discovery.

    Science.gov (United States)

    Praticò, Giulia; Gao, Qian; Scalbert, Augustin; Vergères, Guy; Kolehmainen, Marjukka; Manach, Claudine; Brennan, Lorraine; Pedapati, Sri Harsha; Afman, Lydia A; Wishart, David S; Vázquez-Fresno, Rosa; Lacueva, Cristina Andres; Garcia-Aloy, Mar; Verhagen, Hans; Feskens, Edith J M; Dragsted, Lars O

    2018-01-01

    Identification of new biomarkers of food and nutrient intake has developed fast over the past two decades and could potentially provide important new tools for compliance monitoring and dietary intake assessment in nutrition and health science. In recent years, metabolomics has played an important role in identifying a large number of putative biomarkers of food intake (BFIs). However, the large body of scientific literature on potential BFIs outside the metabolomics area should also be taken into account. In particular, we believe that extensive literature reviews should be conducted and that the quality of all suggested biomarkers should be systematically evaluated. In order to cover the literature on BFIs in the most appropriate and consistent manner, there is a need for appropriate guidelines on this topic. These guidelines should build upon guidelines in related areas of science while targeting the special needs of biomarker methodology. This document provides a guideline for conducting an extensive literature search on BFIs, which will provide the basis to systematically validate BFIs. This procedure will help to prioritize future work on the identification of new potential biomarkers and on validating these as well as other biomarker candidates, thereby providing better tools for future studies in nutrition and health.

  2. Guidelines for Biomarker of Food Intake Reviews (BFIRev: how to conduct an extensive literature search for biomarker of food intake discovery

    Directory of Open Access Journals (Sweden)

    Giulia Praticò

    2018-02-01

    Full Text Available Abstract Identification of new biomarkers of food and nutrient intake has developed fast over the past two decades and could potentially provide important new tools for compliance monitoring and dietary intake assessment in nutrition and health science. In recent years, metabolomics has played an important role in identifying a large number of putative biomarkers of food intake (BFIs. However, the large body of scientific literature on potential BFIs outside the metabolomics area should also be taken into account. In particular, we believe that extensive literature reviews should be conducted and that the quality of all suggested biomarkers should be systematically evaluated. In order to cover the literature on BFIs in the most appropriate and consistent manner, there is a need for appropriate guidelines on this topic. These guidelines should build upon guidelines in related areas of science while targeting the special needs of biomarker methodology. This document provides a guideline for conducting an extensive literature search on BFIs, which will provide the basis to systematically validate BFIs. This procedure will help to prioritize future work on the identification of new potential biomarkers and on validating these as well as other biomarker candidates, thereby providing better tools for future studies in nutrition and health.

  3. Current status on behavioral and biological markers of PTSD: a search for clarity in a conflicting literature.

    Science.gov (United States)

    Zoladz, Phillip R; Diamond, David M

    2013-06-01

    Extensive research has identified stereotypic behavioral and biological abnormalities in post-traumatic stress disorder (PTSD), such as heightened autonomic activity, an exaggerated startle response, reduced basal cortisol levels and cognitive impairments. We have reviewed primary research in this area, noting that factors involved in the susceptibility and expression of PTSD symptoms are more complex and heterogeneous than is commonly stated, with extensive findings which are inconsistent with the stereotypic behavioral and biological profile of the PTSD patient. A thorough assessment of the literature indicates that interactions among myriad susceptibility factors, including social support, early life stress, sex, age, peri- and post-traumatic dissociation, cognitive appraisal of trauma, neuroendocrine abnormalities and gene polymorphisms, in conjunction with the inconsistent expression of the disorder across studies, confounds attempts to characterize PTSD as a monolithic disorder. Overall, our assessment of the literature addresses the great challenge in developing a behavioral and biomarker-based diagnosis of PTSD. Published by Elsevier Ltd.

  4. Carbon dioxide for the recovery of crude oil: a literature search to June 30, 1979. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Doscher, T.

    1980-05-01

    Individual summaries and pertinent commentaries on each of the groups of references into which the literature on carbon dioxide for the recovery of crude oil has been classified are presented in this report. The major classifications are: physical models, laboratory studies, field tests, modelling, patents, and miscellaneous. A special summary that reviews and comments on field operations, fluid handling, and corrosion problems is also included. User's guide and subject categories for the CO/sub 2/ literature survey are given, followed by abstracts of the citations. It is concluded from this survey that the most significant deficiency in research on carbon dioxide flooding for the recovery of crude oil is the paucity of well controlled and interpreted field tests.

  5. Searching for orgasms in the dictionary: language literature and emotion in Lultim patriarca by Najat El Hachmi

    OpenAIRE

    Crameri, Kathryn

    2017-01-01

    L’últim patriarca by Najat El Hachmi (2008) has been critically acclaimed for its portrayal of the difficulties faced by a young Moroccan girl struggling to reconcile her past and present identities under the authoritarian yet unpredictable control of her father. This article focuses on the triangular relationship between language, literature, and emotion that underpins the protagonist’s quest for independence, self-esteem, and emotional maturity. Drawing on research on bilingualism and emoti...

  6. The use of grounded theory in studies of nurses and midwives' coping processes: a systematic literature search.

    Science.gov (United States)

    Cheer, Karen; MacLaren, David; Tsey, Komla

    2015-01-01

    Researchers are increasingly using grounded theory methodologies to study the professional experience of nurses and midwives. To review common grounded theory characteristics and research design quality as described in grounded theory studies of coping strategies used by nurses and midwives. A systematic database search for 2005-2015 identified and assessed grounded theory characteristics from 16 studies. Study quality was assessed using a modified Critical Appraisal Skills Programme tool. Grounded theory was considered a methodology or a set of methods, able to be used within different nursing and midwifery contexts. Specific research requirements determined the common grounded theory characteristics used in different studies. Most researchers did not clarify their epistemological and theoretical perspectives. To improve research design and trustworthiness of grounded theory studies in nursing and midwifery, researchers need to state their theoretical stance and clearly articulate their use of grounded theory methodology and characteristics in research reporting.

  7. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    HPLC analysis reveals the presence of beta amyloid in the OVX and HCL mice brain. .... user interface, good user manual or literature to validate a given program. ... of view, as numbers of citations, ease of usage and computer requirements.

  8. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Drosophila nasuta nasuta and Drosophila nasuta albomicans are cross-fertile races of Drosophila. Hybridization between these races in the laboratory has given rise to new races (Cytoraces), among which karyotypic composition differs from one another and also from those of the parental races. In this study, we search for ...

  9. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    This work is focused on the processes underlying the dynamics of spatially inhomogeneous plankton communities. We demonstrate that reaction—diffusion mathematical models are an appropriate tool for searching and understanding basic mechanisms of complex spatio-temporal plankton dynamics and fractal properties ...

  10. Bioscience methodologies in physical chemistry an engineering and molecular approach

    CERN Document Server

    D'Amore, Alberto

    2013-01-01

    The field of bioscience methodologies in physical chemistry stands at the intersection of the power and generality of classical and quantum physics with the minute molecular complexity of chemistry and biology. This book provides an application of physical principles in explaining and rationalizing chemical and biological phenomena. It does not stick to the classical topics that are conventionally considered as part of physical chemistry; instead it presents principles deciphered from a modern point of view, which is the strength of this book.

  11. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Abstract. The bioassay-guided fractionation of the ethyl acetate extract of the fungus Cochliobolus sp. highlighted leishmanicidalactivity and allowed for anhydrocochlioquinone A (ANDC-A) isolation. MS, 1D and 2D NMR spectra of this compoundwere in agreement with those published in the literature. ANDC-A exhibited ...

  12. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    down. Abstract. Based on a review of mostly recent literature for a public lecture, the question is discussed whether we live in a largely ``top-down” regulated world rather than one formed ``bottom-up” by the resources for plant and animal growth.

  13. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Cyclic adenosine 5′-phosphate (cAMP) is a global regulator of gene expression in Escherichia coli. Despite decades of intensive study, the quantitative effect and regulatory function of cAMP remain the subjects of considerable debate. Here, we analyse the data in the literature to show that: In carbon-limited cultures ...

  14. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Biological functional enrichment; clustering; explorative data analysis; feature selection; gene selection; graph-based learning. ... potential and effectiveness of the proposed model in comparison to the traditional single view clustering models, as well as other existing methods used in the literature for the studied datasets.

  15. 75 FR 64733 - Arcadia Biosciences, Inc.; Filing of Food Additive Petition (Animal Use); Safflower Seed Meal

    Science.gov (United States)

    2010-10-20

    ...] Arcadia Biosciences, Inc.; Filing of Food Additive Petition (Animal Use); Safflower Seed Meal AGENCY: Food... announcing that Arcadia Biosciences, Inc., has filed a petition proposing that the food additive regulations..., Davis, CA 95618. The petition proposes to amend the food additive regulations in part 573 Food Additives...

  16. Harnessing the power of communities: career networking strategies for bioscience PhD students and postdoctoral researchers.

    Science.gov (United States)

    Blackford, Sarah

    2018-04-01

    With an ever more competitive global labour market, coupled with an ever-increasing population of PhD-qualified graduates, the ability to communicate effectively and build strategic connections with others can be advantageous in the job-search process. Whether in pursuit of a tenure-track or non-academic position, many postdoctoral researchers and PhD students will benefit from networking as early as possible to enhance their career prospects. Sometimes viewed cynically as 'using people' or dismissed as 'the old boy network,' the ability to make meaningful connections and build relationships can be more valuable than other job-related skills in order to gain entry to, and progress within, many professions. This mini-review highlights the positive influence of networking and how bioscience PhD students and postdoctoral researchers can harness the power of communities to achieve career success. It is argued that those who make connections and promote personal patronage through networking can gain an advantage over their contemporaries. A summary of key theories and research studies that underpin the practice of networking provides credence to these assertions, which are further substantiated with examples pertinent to the academic community. Although primarily focussed on the biosciences, much of the content is applicable to other scientists at a similar career stage.

  17. SBBN 2010: 7. Congress of the Brazilian Society of Nuclear Biosciences. Radiations in biosciences: advances and trends

    International Nuclear Information System (INIS)

    2010-01-01

    Advance and new perspectives related to the use of ionizing and no ionizing radiations in nuclear biosciences are presented. Multidisciplinary approach, including radiopharmacy, radioprotection and dosimetry, cytogenetic, biosafety, radioecology, environmental toxicology are studied. Topics of Nuclear medicine, radiotherapy and image diagnosis, such as computerized tomography, PET scan, phantoms, biomedical radiography, are reported. Use of radioisotopes, evaluation of radiation dose rates, radiation dose distribution, radiation monitoring is considered. Environmental impact of radiation are also in human beings, animals and for several purposes are analyzed. (MAC)

  18. [Potential for the survey of quality indicators based on a national emergency department registry : A systematic literature search].

    Science.gov (United States)

    Hörster, A C; Kulla, M; Brammen, D; Lefering, R

    2018-06-01

    Emergency department processes are often key for successful treatment. Therefore, collection of quality indicators is demanded. A basis for the collection is systematic, electronic documentation. The development of paper-based documentation into an electronic and interoperable national emergency registry is-besides the establishment of quality management for emergency departments-a target of the AKTIN project. The objective of this research is identification of internationally applied quality indicators. For the investigation of the current status of quality management in emergency departments based on quality indicators, a systematic literature search of the database PubMed, the Cochrane Library and the internet was performed. Of the 170 internationally applied quality indicators, 25 with at least two references are identified. A total of 10 quality indicators are ascertainable by the data set. An enlargement of the data set will enable the collection of seven further quality indicators. The implementation of data of care behind the emergency processes will provide eight additional quality indicators. This work was able to show that the potential of a national emergency registry for the establishment of quality indicators corresponds with the international systems taken into consideration and could provide a comparable collection of quality indicators.

  19. [Advanced online search techniques and dedicated search engines for physicians].

    Science.gov (United States)

    Nahum, Yoav

    2008-02-01

    In recent years search engines have become an essential tool in the work of physicians. This article will review advanced search techniques from the world of information specialists, as well as some advanced search engine operators that may help physicians improve their online search capabilities, and maximize the yield of their searches. This article also reviews popular dedicated scientific and biomedical literature search engines.

  20. Reverse transcription quantitative real-time polymerase chain reaction reference genes in the spared nerve injury model of neuropathic pain: validation and literature search.

    Science.gov (United States)

    Piller, Nicolas; Decosterd, Isabelle; Suter, Marc R

    2013-07-10

    The reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR) is a widely used, highly sensitive laboratory technique to rapidly and easily detect, identify and quantify gene expression. Reliable RT-qPCR data necessitates accurate normalization with validated control genes (reference genes) whose expression is constant in all studied conditions. This stability has to be demonstrated.We performed a literature search for studies using quantitative or semi-quantitative PCR in the rat spared nerve injury (SNI) model of neuropathic pain to verify whether any reference genes had previously been validated. We then analyzed the stability over time of 7 commonly used reference genes in the nervous system - specifically in the spinal cord dorsal horn and the dorsal root ganglion (DRG). These were: Actin beta (Actb), Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), ribosomal proteins 18S (18S), L13a (RPL13a) and L29 (RPL29), hypoxanthine phosphoribosyltransferase 1 (HPRT1) and hydroxymethylbilane synthase (HMBS). We compared the candidate genes and established a stability ranking using the geNorm algorithm. Finally, we assessed the number of reference genes necessary for accurate normalization in this neuropathic pain model. We found GAPDH, HMBS, Actb, HPRT1 and 18S cited as reference genes in literature on studies using the SNI model. Only HPRT1 and 18S had been once previously demonstrated as stable in RT-qPCR arrays. All the genes tested in this study, using the geNorm algorithm, presented gene stability values (M-value) acceptable enough for them to qualify as potential reference genes in both DRG and spinal cord. Using the coefficient of variation, 18S failed the 50% cut-off with a value of 61% in the DRG. The two most stable genes in the dorsal horn were RPL29 and RPL13a; in the DRG they were HPRT1 and Actb. Using a 0.15 cut-off for pairwise variations we found that any pair of stable reference gene was sufficient for the normalization process

  1. Applications of computational tools in biosciences and medical engineering

    CERN Document Server

    Altenbach, Holm

    2015-01-01

     This book presents the latest developments and applications of computational tools related to the biosciences and medical engineering. It also reports the findings of different multi-disciplinary research projects, for example, from the areas of scaffolds and synthetic bones, implants and medical devices, and medical materials. It is also shown that the application of computational tools often requires mathematical and experimental methods. Computational tools such as the finite element methods, computer-aided design and optimization as well as visualization techniques such as computed axial tomography open up completely new research fields that combine the fields of engineering and bio/medical. Nevertheless, there are still hurdles since both directions are based on quite different ways of education. Often even the “language” can vary from discipline to discipline.

  2. Division of Agro technology and Biosciences: Past, Present and Future

    International Nuclear Information System (INIS)

    Khairuddin Abdul Rahim

    2012-01-01

    In presenter speech, he outlined several topics regarding development of Agro technology and Biosciences Division from 31 years ago. This division started with Unit Sains Hidupan Liar under PUSPATI in 1981 and change their names to Program Isotop dan Sinaran dalam Biologi dan Pertanian under Nuclear Technology Unit (UTN) (1983). In 1990 their premise change to MINT-Tech Park. This program responsible for conducting research in agro technology using nuclear technology. Several achievements achieved by this division since established. They also succeed in mutating banana namely Novaria banana (1994), Tongkat Ali rice (1990), ground nut (2003), orchids, organic fertilizer and foliage in 2000. The vision of this division are to promote and enhance innovation and applications in nuclear technology to achieve security in food productivity, safety and quality and ecological awareness for economics competitiveness and vibrancy in agrobioindustry and community development. (author)

  3. Literature database aid

    International Nuclear Information System (INIS)

    Wanderer, J.A.

    1991-01-01

    The booklet is to help with the acquisition of original literature either after a conventional literature search or in particular after a database search. It bridges the gap between abbreviated (short) and original (long) titel. This, together with information on the holdings of technical/scientific libraries, facilitates document delivery. 1500 short titles are listed alphabetically. (orig.) [de

  4. Is LabTutor a helpful component of the blended learning approach to biosciences?

    Science.gov (United States)

    Swift, Amelia; Efstathiou, Nikolaos; Lameu, Paula

    2016-09-01

    To evaluate the use of LabTutor (a physiological data capture and e-learning package) in bioscience education for student nurses. Knowledge of biosciences is important for nurses the world over, who have to monitor and assess their patient's clinical condition, and interpret that information to determine the most appropriate course of action. Nursing students have long been known to find acquiring useable bioscience knowledge challenging. Blended learning strategies are common in bioscience teaching to address the difficulties students have. Student nurses have a preference for hands-on learning, small group sessions and are helped by close juxtaposition of theory and practice. An evaluation of a new teaching method using in-classroom voluntary questionnaire. A structured survey instrument including statements and visual analogue response format and open questions was given to students who participated in Labtutor sessions. The students provided feedback in about the equipment, the learning and the session itself. First year (n = 93) and third year (n = 36) students completed the evaluation forms. The majority of students were confident about the equipment and using it to learn although a few felt anxious about computer-based learning. They all found the equipment helpful as part of their bioscience education and they all enjoyed the sessions. This equipment provides a helpful way to encourage guided independent learning through practice and discovery and because each session is case study based and the relationship of the data to the patient is made clear. Our students helped to evaluate our initial use of LabTutor and found the sessions enjoyable and helpful. LabTutor provides an effective learning tool as part of a blended learning strategy for biosciences teaching. Improving bioscience knowledge will lead to a greater understanding of pathophysiology, treatments and interventions and monitoring. © 2016 John Wiley & Sons Ltd.

  5. Reflective Writing as a Tool for Assessing Teamwork in Bioscience: Insights into Student Performance and Understanding of Teamwork

    Science.gov (United States)

    Mayne, Lynne

    2012-01-01

    To ensure a modern bioscience curriculum that responds to the current needs of stakeholders, there is a need to embed a range of generic capabilities that enables graduates to succeed in and contribute to a rapidly changing world, as well as building strong bioscience skills and knowledge. The curriculum must also prepare students for a rapidly…

  6. Foods: Where Innovation, Agriculture, Molecular Biosciences and Human Nutrition Meet

    Directory of Open Access Journals (Sweden)

    Charles Brennan

    2012-11-01

    Full Text Available There is one commodity the world over that unites mankind—food. In 2011 the United Nations claimed that the world’s population had reached the seven billion mark, a number which is set to increase dramatically in the decades to come. Food security, supply and sustainability are of paramount concern to the future economic and social progress of humanity. It is the responsibility of the food industry, together with food scientists and technologists, to shoulder the burden of ensuring an adequate supply of nutritious, safe and sensorially acceptable foods for a range of demanding consumers. In responding to this challenge, we need to understand the link between agriculture, engineering, food processing, molecular biosciences, human nutrition, commercialisation and innovation. Access to information concerning the composition and quality of foods has never been so easy for consumers and technologists alike. A plethora of research publications are made available each month to scientists and associated interested parties. The outcomes of these research manuscripts are often distilled and disseminated into messages available to everyone through bulletin boards, forums and the popular press. Newspapers and new agencies constantly report on the latest pharma-medical finding, or news regarding food safety and security concerns. We live in an age where information is so readily available to everyone that the task of finding credible and reputable data can be difficult at times. Providing sound evidenced based research is where a peer-reviewed journal can provide clarity. [...

  7. Foods: Where Innovation, Agriculture, Molecular Biosciences and Human Nutrition Meet.

    Science.gov (United States)

    Brennan, Charles

    2012-11-21

    There is one commodity the world over that unites mankind-food. In 2011 the United Nations claimed that the world's population had reached the seven billion mark, a number which is set to increase dramatically in the decades to come. Food security, supply and sustainability are of paramount concern to the future economic and social progress of humanity. It is the responsibility of the food industry, together with food scientists and technologists, to shoulder the burden of ensuring an adequate supply of nutritious, safe and sensorially acceptable foods for a range of demanding consumers. In responding to this challenge, we need to understand the link between agriculture, engineering, food processing, molecular biosciences, human nutrition, commercialisation and innovation. Access to information concerning the composition and quality of foods has never been so easy for consumers and technologists alike. A plethora of research publications are made available each month to scientists and associated interested parties. The outcomes of these research manuscripts are often distilled and disseminated into messages available to everyone through bulletin boards, forums and the popular press. Newspapers and new agencies constantly report on the latest pharma-medical finding, or news regarding food safety and security concerns. We live in an age where information is so readily available to everyone that the task of finding credible and reputable data can be difficult at times. Providing sound evidenced based research is where a peer-reviewed journal can provide clarity. [...].

  8. Environmental Biosciences Program Quarterly Report for Year 3

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2006-04-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  9. MUSC Environmental Biosciences Program First Quarter Report May - June, 2002

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr

    2002-07-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC02-98CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific program, employing a range of research initiatives to identify, study and resolve environmental health risk issues. These initiatives are consistent with the Medical University's role as a comprehensive state-supported health sciences institution and the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable the Medical University to be a national resource for the scientific investigation of environmental health issues. EBP's success in convening worldwide scientific expertise is due in part to the inherent credibility the Medical University brings to the process of addressing these complex issues.

  10. Environmental Biosciences Program Third Quarter Report, Year 2

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2005-03-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  11. Children's Search Engines from an Information Search Process Perspective.

    Science.gov (United States)

    Broch, Elana

    2000-01-01

    Describes cognitive and affective characteristics of children and teenagers that may affect their Web searching behavior. Reviews literature on children's searching in online public access catalogs (OPACs) and using digital libraries. Profiles two Web search engines. Discusses some of the difficulties children have searching the Web, in the…

  12. Children's exposure to environmental pollutants and biomarkers of genetic damage. II. Results of a comprehensive literature search and meta-analysis

    DEFF Research Database (Denmark)

    Neri, Monica; Ugolini, Donatella; Bonassi, Stefano

    2005-01-01

    The present review is based on findings from 178 publications retrieved through an extensive search of the MedLine/PubMed database for a 25 years time period (1980-2004) and 10 manually identified papers. Among the cytogenetic biomarkers that are frequently used in field studies, chromosome...... pollutants, soil and drinking water contaminants, mostly increased CA and, to a lesser extent, MN levels in children. The effect of exposure to airborne urban pollutants was consistently reported by field studies measuring DNA, albumin and hemoglobin adducts. Prenatal (in utero) and postnatal exposure...

  13. Incorporating a Drug Information Consult into a Pharmacy Practice Course to Build Literature Search and Evaluation Skills Through a 3-Stage Model.

    Science.gov (United States)

    Wittman, Deborah; Kovera, Craig; Sullivan, Maureen; Rumore, Martha M

    2017-06-01

    Pharmacy students need to be equipped with skills to research and evaluate literature to effectively apply evidence-based medicine (EBM) in practice. To prepare them, a 3-stage approach to writing a drug information consult (3sDIC) was incorporated into a pharmacy course. The primary objective was to assess students' abilities to retrieve and analyze literature pursuant to a drug information consult. Secondary objectives were to examine feasibility of faculty participation and continuation of the assignment. Ninety students were given a clinical scenario about a patient. The assignment consisted of 3 stages incorporating use of the Population, Intervention, Comparison intervention, Outcome (PICO) method and modified systematic approach (MSA) for stage 1, evaluation of primary literature to write a draft for stage 2, and stage 3, the final consult. All 3 stages were reviewed and graded by faculty. All students completed the 3sDIC, with no grade failures. The rubric employed by faculty was effective, providing students the opportunity to improve the consult. The 3sDIC was found to be feasible with adequate faculty support. The 3sDIC, although not a substitute for a complete drug information course, demonstrated a streamlined approach for Pharmacy year 2 (P2) students to acquire and develop drug information skills.

  14. Design of an Integrated Team Project as Bachelor Thesis in Bioscience Engineering

    Science.gov (United States)

    Peeters, Marie-Christine; Londers, Elsje; Van der Hoeven, Wouter

    2014-01-01

    Following the decision at the KU Leuven to implement the educational concept of guided independent learning and to encourage students to participate in scientific research, the Faculty of Bioscience Engineering decided to introduce a bachelor thesis. Competencies, such as communication, scientific research and teamwork, need to be present in the…

  15. Youtube for millennial nursing students; using internet technology to support student engagement with bioscience.

    Science.gov (United States)

    Johnston, Amy Nb; Barton, Matthew J; Williams-Pritchard, Grant A; Todorovic, Michael

    2018-06-09

    Undergraduate nursing programs typically include students with limited 'on-campus' time who need learning resources that are flexible, technologically appropriate, remotely-accessible (mobile smart devices), and above all, engaging. This has presented academics with challenges surrounding institutional security firewalls, password-access requirements, intellectual property/ownership and staff/student privacy. To overcome these challenges a collection of evidence-based YouTube videos, posted on the Biological Sciences YouTube Channel, supported by the Biosciences in Nurse Education, and underpinned by Benner's pedagogical framework, were developed with the intention of moving students from novice to competent clinical bioscience users. The videos are highly successful; with over 310,000 views, 1.5 million minutes of viewing and more than 5000 subscribers since its inception (YouTube videos was enhanced by their familiarity with the presenter and the breadth of information available in small portions, creating a solid basis for the development of bioscience-competent nursing graduates. Moreover, these open source videos provide a free resource for continual revision and professional development informed by an international minimum bioscience standard for nurses post registration. Crown Copyright © 2018. Published by Elsevier Ltd. All rights reserved.

  16. Predictors of academic performance in the discipline-specific bioscience paper: a retrospective qualitative study.

    Science.gov (United States)

    Khareedi, R

    2018-05-01

    The cohort of students enrolled in the discipline-specific bioscience paper reflects a structural diversity in that it includes students of multiple ethnicities, varied age groups, differing scholastic and life experiences. These divergent identities of students are known to influence academic performance. The purpose of this retrospective quantitative study was to determine the ability of a set of variables such as age, gender, ethnicity, level of prior education, the place from which prior education was obtained, work experience and prior academic achievement to predict academic performance in the discipline-specific bioscience paper. The sample for this study was a purposive sample of all oral health students who had enrolled in the paper at the Auckland University of Technology from 2011 to 2014. The desensitised empirical data of 116 students from the University's database were subject to multivariable regression analysis. Pearson's correlation coefficients were calculated. Prior academic achievement was a statistically significant predictor variable (P academic performance in the discipline-specific bioscience paper and was also positively correlated (r = 0.641, P academic achievement was the only variable that was demonstrated to be correlated to and predictive of the academic performance in the discipline-specific bioscience paper. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  17. 77 FR 56175 - Arcadia Biosciences, Inc.; Filing of Food Additive Petition (Animal Use)

    Science.gov (United States)

    2012-09-12

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Part 573 [Docket No. FDA-2012-F-0949] Arcadia Biosciences, Inc.; Filing of Food Additive Petition (Animal Use) AGENCY: Food... 573 Food Additives Permitted in Feed and Drinking Water of Animals (21 CFR part 573) to provide for...

  18. Motivation in pediatric motor rehabilitation: A systematic search of the literature using the self-determination theory as a conceptual framework.

    Science.gov (United States)

    Meyns, Pieter; Roman de Mettelinge, Tine; van der Spank, Judith; Coussens, Marieke; Van Waelvelde, Hilde

    2017-03-09

    Motivation is suggested as an important factor in pediatric motor rehabilitation. Therefore, we reviewed the existing evidence of (motivational) motor rehabilitation paradigms, and how motivation influences rehabilitation outcome using self-determination theory as conceptual framework. PubMed and Web-of-Science databases were systematically searched until June 2015. Data were independently extracted and critiqued for quality by three authors. Studies reporting motivational aspects were included. Most studies examined new technology (e.g., virtual reality [VR]). Out of 479 records, three RCT, six case-control, and six non-comparative studies were included with mixed quality. Motivation was rarely reported. Training individualization to the child's capabilities with more variety seemed promising to increase motivation. Motivation increased when the exercises seemed helpful for daily activities. Motivation in pediatric rehabilitation should be comprehensively assessed within a theoretical framework as there are indications that motivated children have better rehabilitation outcomes, depending on the aspect of motivation.

  19. Urananite leaching: literature survey

    Energy Technology Data Exchange (ETDEWEB)

    Grisham, G.F.; Bryant, E.A.; Williams, K.E.

    1979-04-01

    A literature survey was undertaken to provide background materials for a series of experiments involving the interaction of spent uranium dioxide fuel with various environments. Notes and references pertaining to the basic properties of UO/sub 2/ as produced and after reactor exposure are presented. The use of computerized literature searches is illustrated with specific topics related to leaching experiments. 57 references.

  20. Urananite leaching: literature survey

    International Nuclear Information System (INIS)

    Grisham, G.F.; Bryant, E.A.; Williams, K.E.

    1979-04-01

    A literature survey was undertaken to provide background materials for a series of experiments involving the interaction of spent uranium dioxide fuel with various environments. Notes and references pertaining to the basic properties of UO 2 as produced and after reactor exposure are presented. The use of computerized literature searches is illustrated with specific topics related to leaching experiments. 57 references