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Sample records for bioscience limited anti-c

  1. Environmental Biosciences Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2007-01-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the DOE. Plans for restructuring the performance schedule of the trichloroethylene projects have been submitted to the department. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this

  2. Anti-C1q autoantibodies.

    Science.gov (United States)

    Kallenberg, Cees G M

    2008-09-01

    Autoantibodies to complement components are associated with various diseases. Anti-C1q antibodies are present in all patients with hypocomplementemic urticarial vasculitis, but also, with varying prevalence, in other conditions. In SLE, these antibodies are neither sensitive nor specific for this condition. They occur, however, more frequently in (proliferative) lupus nephritis, particularly during active disease. Furthermore, levels of anti-C1q rise, in many cases, prior to a relapse of lupus nephritis, suggesting a pathogenic role for the autoantibodies. Indeed, experimental studies strongly support a pathogenic role for anti-C1q in immune complex-mediated renal disease. In addition, anti-C1q may interfere with the clearance of apoptotic cells, so influencing induction and expression of autoimmunity. PMID:18606253

  3. Anti-C1q autoantibodies

    NARCIS (Netherlands)

    Kallenberg, Cees G. M.

    2008-01-01

    Autoantibodies to complement components are associated with various diseases. Anti-C1q antibodies are present in all patients with hypocomplementemic urticarial vasculitis, but also, with varying prevalence, in other conditions. In SLE, these antibodies are neither sensitive nor specific for this co

  4. Environmental Biosciences Program Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2007-07-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the DOE. Plans for restructuring the performance schedule of the trichloroethylene projects have been submitted to the department. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this

  5. Environmental Biosciences Program Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2006-10-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this cooperative agreement can be forwarded to Dr. Lawrence C. Mohr in the EBP office of the Medical University of South Carolina at (843) 792-1532.

  6. Environmental Biosciences First Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2003-09-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risk issues. These initiatives are consistent with the Medical University's role as a comprehensive state-supported health sciences institution and the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable the Medical University to be a national resource for the scientific investigation of environmental health issues. EBP's success in convening worldwide scientific expertise is due in part to the inherent credibility the Medical University brings to the process of addressing these complex issues. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), asbestos and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  7. Environmental Biosciences Program Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2008-01-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the DOE. Plans for restructuring the performance schedule of the trichloroethylene projects have been submitted to the department. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  8. Environmental Biosciences Program Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2009-01-30

    Current research projects have focused Environmental Biosciences Program (EBP) talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene, low-dose ionizing radiation (gamma and neutron) and alpha radiation from plutonium. Trichloroethylene research has been conducted as a joint collaborative effort with the University of Georgia. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the United States Department of Energy (DOE). Laboratory work has been completed on several trichloroethylene risk assessment projects, and these projects have been brought to a close. Plans for restructuring the performance schedule of the remaining trichloroethylene projects have been submitted to the department. A comprehensive manuscript on the scientific basis of trichloroethylene risk assessment is in preparation. Work on the low-dose radiation risk assessment projects is also progressing at a slowed rate as a result of funding uncertainties. It has been necessary to restructure the proponency and performance schedule of these projects, with the project on Low-Dose Radiation: Epidemiology Risk Models transferred to DOE Office of Science proponency under a separate funding instrument. Research on this project will continue under the provisions of the DOE Office of Science funding instrument, with progress reported in accordance with the requirements of that funding instrument. Progress on that project will no longer be reported in quarterly reports for DE-FC09-02CH11109. Following a meeting at the Savannah River Site on May 8, 2008, a plan was submitted for development of an epidemiological cohort study and prospective medical surveillance system for the assessment of disease rates among workers at the Savannah River

  9. KDE Bioscience: platform for bioinformatics analysis workflows.

    Science.gov (United States)

    Lu, Qiang; Hao, Pei; Curcin, Vasa; He, Weizhong; Li, Yuan-Yuan; Luo, Qing-Ming; Guo, Yi-Ke; Li, Yi-Xue

    2006-08-01

    Bioinformatics is a dynamic research area in which a large number of algorithms and programs have been developed rapidly and independently without much consideration so far of the need for standardization. The lack of such common standards combined with unfriendly interfaces make it difficult for biologists to learn how to use these tools and to translate the data formats from one to another. Consequently, the construction of an integrative bioinformatics platform to facilitate biologists' research is an urgent and challenging task. KDE Bioscience is a java-based software platform that collects a variety of bioinformatics tools and provides a workflow mechanism to integrate them. Nucleotide and protein sequences from local flat files, web sites, and relational databases can be entered, annotated, and aligned. Several home-made or 3rd-party viewers are built-in to provide visualization of annotations or alignments. KDE Bioscience can also be deployed in client-server mode where simultaneous execution of the same workflow is supported for multiple users. Moreover, workflows can be published as web pages that can be executed from a web browser. The power of KDE Bioscience comes from the integrated algorithms and data sources. With its generic workflow mechanism other novel calculations and simulations can be integrated to augment the current sequence analysis functions. Because of this flexible and extensible architecture, KDE Bioscience makes an ideal integrated informatics environment for future bioinformatics or systems biology research. PMID:16260186

  10. Anti-C1q antibodies in systemic lupus erythematosus

    DEFF Research Database (Denmark)

    Orbai, A-M; Truedsson, L; Sturfelt, G;

    2015-01-01

    OBJECTIVE: Anti-C1q has been associated with systemic lupus erythematosus (SLE) and lupus nephritis in previous studies. We studied anti-C1q specificity for SLE (vs rheumatic disease controls) and the association with SLE manifestations in an international multicenter study. METHODS: Information...... serologies. Anti-C1q in combination with anti-dsDNA and low complement was the strongest serological association with renal involvement. These data support the usefulness of anti-C1q in SLE, especially in lupus nephritis....

  11. The Application of Magnetic Techniques in Biosciences

    OpenAIRE

    Safarikova, M.; Safarik, I.

    2001-01-01

    The idea to use magnetic techniques in biosciences is not new, but it has enjoyed a resurgence of interest especially during the last two decades. Magnetic adsorbents, carriers and modifiers can be used for the immobilization, isolation, modification, detection, determination and removal of a variety of biologically active compounds, xenobiotics, cellular components and cells. Magnetic separation and labelling have recently found many useful and interesting applications in various areas of bi...

  12. Nitrogen-15 reference book: medicine and biosciences

    International Nuclear Information System (INIS)

    A comprehensive bibliography on the application of the stable nitrogen isotope 15N in medicine, animal nutrition and physiology, biosciences, and related disciplines is presented. The literature pertaining to this paper covers the period from 1977 to 1981. The references are completed by an index of all authors and a subject index with special emphasis to the used organisms, labelled compounds, and tracer techniques, respectively. (author)

  13. Developing Research Capabilities in Energy Biosciences

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Donald D

    2008-01-01

    Scientists founded the Life Sciences Research Foundation (LSRF) in 1983 as a non-profit pass through foundation that awards post doctoral fellowships in all areas of the life sciences. LSRF scientists review hundreds of applications each year from PhDs seeking support. For example this year, our 26th, we received 800 applications and our peer review committee will choose about 50 finalists who are eligible for these awards. We have no endowment so we solicit sponsors each year. The fellowships are sponsored by research oriented companies, foundations, philanthropists, the Howard Hughes Medical Institute, and other organizations who believe in the value of awarding fellowships to the best and the brightest young scientists. Our web site has a complete listing of all details about LSRF (http://www.lsrf.org/). In the late 1980s the Division of Bioscience in the Office of Basic Energy Science, a granting agency of the Department of Energy, joined this partnership. Bioscience's mandate was to support non-medical microbiology and plant sciences. LSRF received a series of 5 year grants from DOE to award fellowships to our top applicants in these fields of research. We began to support DOE-Energy Bioscience post doctoral fellows in 1989. From 1989 through 2004 when DOE funding ended our partnership awarded 41 DOE-Energy Bioscience Fellows of the Life Sciences Research Foundation. Each of these was a three year fellowship. DOE-Energy Biosciences was well matched with LSRF. Our extensive peer review screened applicants in all areas of the life sciences. Most LSRF sponsors are interested in supporting fellows who work on diseases. At the time that we began our partnership with DOE we had no sponsors willing to support plant biology and non medical microbiology. For 15 years DOE played a major role in the training of the very best young scientists in these important fields of research simply through its support of LSRF post doctoral fellows. Young scientists interested in

  14. Anti-C1q in systemic lupus erythematosus.

    Science.gov (United States)

    Stojan, G; Petri, M

    2016-07-01

    C1q is the first component of the classical complement pathway. Both clinically validated in-house ELISA assays as well as commercial ELISA kits are used for detection of anti-C1q antibodies. Anti-C1q autoantibodies can be detected in a wide range of autoimmune diseases and are highly sensitive for hypocomplementemic uticarial vasculitis. In SLE, anti-C1q are strongly associated with proliferative lupus nephritis, and their absence carries a negative predictive value for development of lupus nephritis of close to 100%. Anti-C1q in combination with anti-dsDNA and low complement has the strongest serological association with renal involvement. The anti-C1q titers correlate with global disease activity scores in patients with renal involvement, and higher titers seem to precede renal flares. After the successful treatment of a renal flare, anti-C1q has the tendency to decrease or even become undetectable. The main obstacle to the inclusion of anti-C1q in the classification criteria and clinical management of SLE is the lack of standardized laboratory assays. PMID:27252264

  15. Introducing bioinformatics, the biosciences' genomic revolution

    CERN Document Server

    Zanella, Paolo

    1999-01-01

    The general audience for these lectures is mainly physicists, computer scientists, engineers or the general public wanting to know more about what’s going on in the biosciences. What’s bioinformatics and why is all this fuss being made about it ? What’s this revolution triggered by the human genome project ? Are there any results yet ? What are the problems ? What new avenues of research have been opened up ? What about the technology ? These new developments will be compared with what happened at CERN earlier in its evolution, and it is hoped that the similiraties and contrasts will stimulate new curiosity and provoke new thoughts.

  16. Environmental Biosciences Quarterly Report, September - December, 2005

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2006-01-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  17. Environmental Biosciences Program Report for Year 2

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2005-10-15

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  18. Environmental Biosciences Program Fourth Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.d.

    2003-04-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific program, employing a range of research initiatives to identify, study and resolve environmental health risk issues. These initiatives are consistent with the Medical University's role as a comprehensive state-supported health sciences institution and the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable the Medical University to be a national resource for the scientific investigation of environmental health issues. EBP's success in convening worldwide scientific expertise is due in part to the inherent credibility the Medical University brings to the process of addressing these complex issues.

  19. The Bioscience Nuclear Microscopy Program at LLNL

    Energy Technology Data Exchange (ETDEWEB)

    Bench, G.; Freeman, S.; Roberts, M.; Sideras-Haddad, E.

    1996-12-31

    Since initiation in mid 1994, a bioscience nuclear microscopy program at Livermore has enabled collaboration with bio-scientists on a variety of projects requiring quantitative elemental microanalysis. For microprobe analysis a combination of PIXE and STIM are typically used; respectively generating element distribution maps with micron scale spatial resolution, and projected densities and histological information with sub-micron spatial resolution. Current studies demonstrate the applicability of nuclear microscopy (particularly when combined with other analysis techniques) in environmental tracing, toxicology, carcinogenesis, and structural biology. The program currently uses {approximately}10 percent of the available time on a 10 MV tandem accelerator that is also applied to a variety of Accelerator Mass Spectrometry and other microprobe programs. The completion of a dedicated nuclear microprobe system, using a 5 SDH NEC 1.7 MV tandem accelerator and employing several energy dispersive x-ray detectors to improve x-ray counting rates, promises increased accelerator access, greater sample throughput and continued expansion of the program.

  20. Environmental Biosciences Program Fourth Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2004-06-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), asbestos and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  1. Environmental Biosciences Program Third Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2004-03-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), asbestos and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  2. Environmental Biosciences Program Second Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2003-12-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), asbestos and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  3. Environmental Biosciences Program Report for Year Three

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2006-07-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  4. Second Quarter Report Environmental Biosciences Program

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2002-10-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific program, employing a range of research initiatives to identify, study and resolve environmental health risk issues. These initiatives are consistent with the Medical University's role as a comprehensive state-supported health sciences institution and the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable the Medical University to be a national resource for the scientific investigation of environmental health issues. EBP's success in convening worldwide scientific expertise is due in part to the inherent credibility the Medical University brings to the process of addressing these complex issues.

  5. Environmental Biosciences Program Third Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2003-01-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific program, employing a range of research initiatives to identify, study and resolve environmental health risk issues. These initiatives are consistent with the Medical University's role as a comprehensive state-supported health sciences institution and the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable the Medical University to be a national resource for the scientific investigation of environmental health issues. EBP's success in convening worldwide scientific expertise is due in part to the inherent credibility the Medical University brings to the process of addressing these complex issues.

  6. Lessons on Ethical Decision Making from the Bioscience Industry

    OpenAIRE

    Novas, Carlos

    2006-01-01

    Novas discusses the implications of a new study in PLoS Medicine, in which executives and senior managers from bioscience firms were asked what their companies were doing to promote ethical behaviour.

  7. Introducing Advances in Bioscience and Clinical Medicine (ABCmed)

    OpenAIRE

    Samad EJ Golzari; Kamyar Ghabili

    2013-01-01

    We are pleased to announce the launch of the Advances in Bioscience and Clinical Medicine (ABCmed), aninternational open-access, and peer-reviewed journal. Mostly intended to cover all areas of bioscience and medicine, theJournal would provide a unique venue for the scientists from all over the world to publish their scientific works. One ofthe advantages of publishing with us is the rapid yet rigorous review process which is mostly performed by ourdistinguished Editorial and Review Board mem...

  8. The ACCM Beamlines For Bioscience Studies

    International Nuclear Information System (INIS)

    To meet the increasing demand of X-ray beamlines for bioscience research, we have designed two high-performance, side-branch, asymmetric-cut curved crystal monochromator (ACCM) beamlines to fully utilize the sideway output of the superconducting wiggler SW6 at NSRRC. Each of these two beamlines (BL13A and BL13C) collects 1 mrad of the radiation fan in the horizontal direction, one centered at 3 mrad and the other at 4 mrad away from the central line of the wiggler output. The newly designed ACCMs are capable of energy scanning from 12 keV to 14 keV and offer good performances in terms of flux, resolution and stability. The ACCMs are designed and built in-house, combining efficient cooling and bending mechanisms in a compact unit that allows precise adjustments on a goniometer assembly. The bender is specially designed with symmetrically driven piezo-actuators that minimize center displacement during bending. Both direct and indirect cooling methods were tested; the former using Ga/In directly under the beam footprint and the latter using both sides of the crystal clamping area for cooling. Performance of the beamlines employing both cooling methods has been measured. The indirect cooling method provides 4.9 x 1010 photons/sec through a pair of 100 μm slits (H x V) with energy resolution of 5.3 x 10-3 (ΔE/E) at 12.7 keV. Higher energy resolution in the 10-4 range can be achieved by adjusting the horizontal source fan or the crystal radius at the expense of flux. The direct cooling method provides 1.4 x 1010 photons/sec through a pair of 100 μm slits (H x V) with energy resolution of 1.2 x 10-3 (ΔE/E) at 12.7 keV. The FWHM of the focused beam profile in the indirect cooling mode is 800 x 109 μm (H x V), and 800 x 283 μm (H x V) in the direct cooling mode with some horizontal tail, the latter being larger due to influence of the Ga/In layer on the crystal shape. Cooling efficiency is excellent in the direct cooling mode, in which the performance stabilizes in a

  9. Environmental Biosciences Program Fourth Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2005-06-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation s need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyles (PCBs), and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this cooperative agreement can be forwarded to Dr. Lawrence C. Mohr in the EBP office of the Medical University of South Carolina at (843) 792-1532.

  10. Environmental Biosciences Report for Year 3

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2007-10-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the DOE. Plans for restructuring the performance schedule of the trichloroethylene projects have been submitted to the department. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk based decision-making. Questions, comments or requests for further information concerning the activities under this

  11. Environmental Biosciences Program Second Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2004-12-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this cooperative agreement can be forwarded to Dr. Lawrence C. Mohr in the EBP office of the Medical University of South Carolina at (843) 792-1532.

  12. Environmental Biosciences Program Report for Year 3

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2007-04-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the DOE. Plans for restructuring the performance schedule of the trichloroethylene projects have been submitted to the department. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this

  13. Teaching and learning about bioscience ethics with undergraduates.

    Science.gov (United States)

    Van Rooy, Wilhelmina; Pollard, Irina

    2002-01-01

    Bioscience ethics acts as a practical interface between science and bioethics. It links scientific endeavour and its application into adaptive forms of bioethical consensus. Its major elements are increased understanding of biological systems, responsible use of technology, and curtailment of ethnocentric debates in tune with new scientific insights. This paper briefly describes the students' learning experience gained from the vacation unit BIOL 240, Introduction to Bioscience Ethics, as taught in biology, Macquarie University. On the basis of our evidence students were overwhelmingly positive about their learning because the unit assisted them to better face dilemmas that arise from the application of science and technology. The structure also provided active engagement with the subject matter and preferred learning environments that supported and contested their understanding of concepts relevant to bioscience and bioethics. PMID:14741947

  14. Anti-C1q Autoantibodies, Novel Tests, and Clinical Consequences

    OpenAIRE

    Mahler, Michael; van Schaarenburg, Rosanne A.; Trouw, Leendert A.

    2013-01-01

    Although anti-C1q autoantibodies have been described more than four decades ago a constant stream of papers describing clinical associations or functional consequences highlights that anti-C1q antibodies are still hot and happening. By far the largest set of studies focus on anti-C1q antibodies is systemic lupus erythematosus (SLE). In SLE anti-C1q antibodies associate with involvement of lupus nephritis in such a way that in the absence of anti-C1q antibodies it is unlikely that a flare in n...

  15. Challenges in Understanding Photosynthesis in a University Introductory Biosciences Class

    Science.gov (United States)

    Södervik, Ilona; Virtanen, Viivi; Mikkilä-Erdmann, Mirjamaija

    2015-01-01

    University students' understanding of photosynthesis was examined in a large introductory biosciences class. The focus of this study was to first examine the conceptions of photosynthesis among students in class and then to investigate how a certain type of text could enhance students' understanding of photosynthesis. The study was based on pre-…

  16. Dispatches from the Interface of Salivary Bioscience and Neonatal Research

    OpenAIRE

    KristinVoegtline; DouglasA.Granger

    2014-01-01

    The emergence of the interdisciplinary field of salivary bioscience has created opportunity for neonatal researchers to measure multiple components of biological systems non-invasively in oral fluids. The implications are profound and potentially high impact. From a single oral fluid specimen, information can be obtained about a vast array of biological systems (e.g., endocrine, immune, autonomic nervous system) and the genetic polymorphisms related to individual differences in their function...

  17. Bioscience methodologies in physical chemistry an engineering and molecular approach

    CERN Document Server

    D'Amore, Alberto

    2013-01-01

    The field of bioscience methodologies in physical chemistry stands at the intersection of the power and generality of classical and quantum physics with the minute molecular complexity of chemistry and biology. This book provides an application of physical principles in explaining and rationalizing chemical and biological phenomena. It does not stick to the classical topics that are conventionally considered as part of physical chemistry; instead it presents principles deciphered from a modern point of view, which is the strength of this book.

  18. Fluorescence lifetime imaging in biosciences: technologies and applications

    Institute of Scientific and Technical Information of China (English)

    Raluca NIESNER; Karl-Heinz GERICKE

    2008-01-01

    The biosciences require the development of methods that allow a non-invasive and rapid investigation of biological systems. In this aspect, high-end imaging tech-niques allow intravital microscopy in real-time, providing information on a molecular basis. Far-field fluorescence imaging techniques are some of the most adequate methods for such investigations. However, there are great differences between the common fluorescence imaging techniques, i.e., wide-field, confocal one-photon and two-photon microscopy, as far as their applicability in diverse bioscientific research areas is concerned. In the first part of this work, we briefly compare these techniques. Standard methods used in the biosciences, i.e., steady-state techniques based on the analy-sis of the total fluorescence signal originating from the sam-ple, can successfully be employed in the study of cell, tissue and organ morphology as well as in monitoring the macro-scopic tissue function. However, they are mostly inadequate for the quantitative investigation of the cellular function at the molecular level. The intrinsic disadvantages of steady-state techniques are countered by using time-resolved tech-niques. Among these fluorescence lifetime imaging (FLIM) is currently the most common. Different FLIM principles as well as applications of particular relevance for the biosci-ences, especially for fast intravital studies are discussed in this work.

  19. Challenges and opportunities for early-career Teaching-Focussed academics in the biosciences.

    Science.gov (United States)

    Hubbard, Katharine; Gretton, Sarah; Jones, Katherine; Tallents, Lucy

    2015-01-01

    Twenty-seven percent of academics in UK Higher Education (HE) are in Teaching-Focussed positions, making major contributions to undergraduate programmes in an era of high student expectations when it comes to teaching quality. However, institutional support for Teaching-Focussed academics is often limited, both in terms of peer networking and opportunities for career development. As four early-career stage Teaching-Focussed academics working in a variety of institutions, we explore what motivated our choices to make teaching our primary academic activity, and the challenges that we have faced in doing so. In addition to highlighting the need for universities to fully recognise the achievements of teaching staff, we discuss the role that the various biosciences learned societies have in supporting Teaching-Focussed academics. We identify that there is a need for the learned societies to come together and pool their expertise in this area. The fragmented nature of the Teaching-Focussed academic community means that clear sources of national support are needed in order to best enable the next generation of bioscience educators to reach their full potential. PMID:25977754

  20. SBBN 2010: 7. Congress of the Brazilian Society of Nuclear Biosciences. Radiations in biosciences: advances and trends

    International Nuclear Information System (INIS)

    Advance and new perspectives related to the use of ionizing and no ionizing radiations in nuclear biosciences are presented. Multidisciplinary approach, including radiopharmacy, radioprotection and dosimetry, cytogenetic, biosafety, radioecology, environmental toxicology are studied. Topics of Nuclear medicine, radiotherapy and image diagnosis, such as computerized tomography, PET scan, phantoms, biomedical radiography, are reported. Use of radioisotopes, evaluation of radiation dose rates, radiation dose distribution, radiation monitoring is considered. Environmental impact of radiation are also in human beings, animals and for several purposes are analyzed. (MAC)

  1. Students Turned Off by Turnitin? Perception of Plagiarism and Collusion by Undergraduate Bioscience Students

    Science.gov (United States)

    Thompsett, Andrew; Ahluwalia, Jatinder

    2010-01-01

    Research on undergraduate bioscience students and the incidence of plagiarism is still in its infancy and a key problem arises in gauging the perception of undergraduate students on plagiarism and collusion in biosciences subjects because of the lack of empirical data. The aim of this study was to provide qualitative data on the perceptions of…

  2. Call for Papers-Bioscience Methods(ISSN 1925-1920)

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Bioscience Methods (BM) (ISSN 1925-1920) is a new launched, open access and peer-reviewed journal that dedicates to publish the original research papers involving in innovative technologies and novel experimental arts within the fields of biosciences.

  3. Applications of computational tools in biosciences and medical engineering

    CERN Document Server

    Altenbach, Holm

    2015-01-01

     This book presents the latest developments and applications of computational tools related to the biosciences and medical engineering. It also reports the findings of different multi-disciplinary research projects, for example, from the areas of scaffolds and synthetic bones, implants and medical devices, and medical materials. It is also shown that the application of computational tools often requires mathematical and experimental methods. Computational tools such as the finite element methods, computer-aided design and optimization as well as visualization techniques such as computed axial tomography open up completely new research fields that combine the fields of engineering and bio/medical. Nevertheless, there are still hurdles since both directions are based on quite different ways of education. Often even the “language” can vary from discipline to discipline.

  4. Division of Agro technology and Biosciences: Past, Present and Future

    International Nuclear Information System (INIS)

    In presenter speech, he outlined several topics regarding development of Agro technology and Biosciences Division from 31 years ago. This division started with Unit Sains Hidupan Liar under PUSPATI in 1981 and change their names to Program Isotop dan Sinaran dalam Biologi dan Pertanian under Nuclear Technology Unit (UTN) (1983). In 1990 their premise change to MINT-Tech Park. This program responsible for conducting research in agro technology using nuclear technology. Several achievements achieved by this division since established. They also succeed in mutating banana namely Novaria banana (1994), Tongkat Ali rice (1990), ground nut (2003), orchids, organic fertilizer and foliage in 2000. The vision of this division are to promote and enhance innovation and applications in nuclear technology to achieve security in food productivity, safety and quality and ecological awareness for economics competitiveness and vibrancy in agrobioindustry and community development. (author)

  5. Dispatches from the Interface of Salivary Bioscience and Neonatal Research

    Directory of Open Access Journals (Sweden)

    KristinVoegtline

    2014-03-01

    Full Text Available The emergence of the interdisciplinary field of salivary bioscience has created opportunity for neonatal researchers to measure multiple components of biological systems non-invasively in oral fluids. The implications are profound and potentially high impact. From a single oral fluid specimen, information can be obtained about a vast array of biological systems (e.g., endocrine, immune, autonomic nervous system and the genetic polymorphisms related to individual differences in their function. The purpose of this review is to describe the state of the art for investigators interested in integrating these unique measurement tools into the current and next generation of research on gonadal steroid exposure during the prenatal and neonatal developmental periods

  6. Introducing Advances in Bioscience and Clinical Medicine (ABCmed

    Directory of Open Access Journals (Sweden)

    Samad EJ Golzari

    2013-07-01

    Full Text Available We are pleased to announce the launch of the Advances in Bioscience and Clinical Medicine (ABCmed, aninternational open-access, and peer-reviewed journal. Mostly intended to cover all areas of bioscience and medicine, theJournal would provide a unique venue for the scientists from all over the world to publish their scientific works. One ofthe advantages of publishing with us is the rapid yet rigorous review process which is mostly performed by ourdistinguished Editorial and Review Board members; this obviously hard-to-achieve goal would not be realized withouttheir continuous support and advice.Another distinguishing characteristic of ABCmed is the diversity of published items in each issue. The editorial team ofthe Journal has devoted separate sections to rather unknown yet interesting fields of the science for instance hypotheses,history of medicine, etc. In the first issue of ABCmed, the readers might refer to the two published hypotheseshighlighting the possible role of chamomile in the treatment of rheumatoid arthritis, and also the preventive effects oftadalafil together with nimodipine in subarachnoid hemorrhage-induced cerebral vasospasm.Letters to the Editor are one of the major sectors in the ABCmed providing not only further on the already publisheddata in the Journal, but also personal comments on the major public health concerns and medical issues. In the firstissue of the Journal, a very important cancer surgery complication is debated, introducing different strategies in the painmanagement of breast cancer patients.We hope that ABCmed will provide a basis to bring together the scientists from all over the globe with the same goal ofpromoting science.

  7. Case report: Severe hemolytic disease of the fetus and newborn due to anti-C+G.

    Science.gov (United States)

    Jernman, Riina; Stefanovic, Vedran; Korhonen, Anu; Haimila, Katri; Sareneva, Inna; Sulin, Kati; Kuosmanen, Malla; Sainio, Susanna

    2015-01-01

    Anti-G is commonly present with anti-D and/or anti-C and can confuse serological investigations. in general, anti-G is not considered a likely cause of severe hemolytic disease of the fetus and newborn (HDFN), but it is important to differentiate it from anti-D in women who should be administered anti-D immunoglobulin prophylaxis. We report one woman with three pregnancies severely affected by anti-C+G requiring intrauterine treatment and a review of the literature. In our case, the identification of the correct antibody was delayed because the differentiation of anti-C+G and anti-D+C was not considered important during pregnancy since the father was D-. In addition, anti-C+G and anti-G titer levels were not found to be reliable as is generally considered in Rh immunization. Severe HDFN occurred at a maternal anti-C+G antibody titer of S and anti-G titer of 1 in comparison with the critical titer level of 16 or more in our laboratory. close collaboration between the immunohematology laboratory and the obstetric unit is essential. In previously affected families, early assessment for fetal anemia is required even when titers are low. PMID:26829179

  8. Production of the superheavy baryon Λc anti c*(4209) in kaon-induced reaction

    International Nuclear Information System (INIS)

    The production of superheavy Λc anti c*(4209) baryon in the K-p → ηcΛ process via s-channel is investigated with an effective Lagrangian approach and the isobar model. Moreover, the background from the K-p → ηcΛ reaction through the t-channel with K* exchange and u-channel with nucleon exchange are also considered. The numerical results indicate it is feasible to search for the superheavy Λc anti c*(4209) via K-p scattering. The relevant calculations not only shed light on the further experiment of searching for the Λc anti c*(4209) through kaon-induced reaction, but also enable us to have a better understanding of the exotic baryons. (orig.)

  9. Anti Rh Hemolytic Disease due to Anti C Antibody: Is Testing for Anti D Antibodies Enough?

    OpenAIRE

    Negi, Gita; Singh, Gaur Dushyant

    2011-01-01

    Rh blood group system is a complex blood group system. Rh antibodies are produced in Rh negative individuals following exposure to foreign RBCs after transfusion or pregnancy. Anti C is a rare cause of hemolytic disease of newborn and is very scarcely reported in the literature. The aim of the present case report of Hemolytic disease caused by Anti C antibody is to bring out the fact that antibodies other than anti D should be considered in cases that give a suggestive history but no evidence...

  10. Developing and evaluating effective bioscience learning activities for nursing students.

    Science.gov (United States)

    Salvage-Jones, Judith; Hamill, Jessie; Todorovic, Michael; Barton, Matthew J; Johnston, Amy N B

    2016-07-01

    Effective engagement of nursing students in the study of biosciences remains a challenge for many tertiary institutes. In this study we attempted to implement and then evaluate a simple hands-on intervention, consisting of a series of hands-on games and puzzles, to increase nursing student engagement with core concepts and anatomical learning involved in clinical anatomy and physiology. The study used a quazi-experimental longitudinal before and after design, to explore the effect of a learning intervention on student performance. Set across three different campuses of the same University, it included 1320 first year undergraduate nursing students from 2013 to 2014 who were studying Anatomy and Physiology. Students were exposed to the interventions or not, and concomitant academic performance, weekly quiz scores, performance in fortnightly worksheets and, across the semester, exam performance were compared. The results show that while the intervention appeared to increase academic performance in students on one campus (2013) compared to the other two, this difference was not sustained into 2014 when a bigger cohort was examined. Despite significant subjective student satisfaction and enthusiasm about these learning and teaching interventions, the data does not support the capacity of these activities to enhance student academic performance. Tertiary entrance scores, being a non-native English speakers and socio-economic status all had a bigger impact on student performance than engagement with fun anatomy and physiology activities. PMID:27428695

  11. Environmental Biosciences Program Quarterly Report for Year 3

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2006-04-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  12. Environmental Biosciences Program Third Quarter Report, Year 2

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2005-03-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  13. Foods: Where Innovation, Agriculture, Molecular Biosciences and Human Nutrition Meet

    Directory of Open Access Journals (Sweden)

    Charles Brennan

    2012-11-01

    Full Text Available There is one commodity the world over that unites mankind—food. In 2011 the United Nations claimed that the world’s population had reached the seven billion mark, a number which is set to increase dramatically in the decades to come. Food security, supply and sustainability are of paramount concern to the future economic and social progress of humanity. It is the responsibility of the food industry, together with food scientists and technologists, to shoulder the burden of ensuring an adequate supply of nutritious, safe and sensorially acceptable foods for a range of demanding consumers. In responding to this challenge, we need to understand the link between agriculture, engineering, food processing, molecular biosciences, human nutrition, commercialisation and innovation. Access to information concerning the composition and quality of foods has never been so easy for consumers and technologists alike. A plethora of research publications are made available each month to scientists and associated interested parties. The outcomes of these research manuscripts are often distilled and disseminated into messages available to everyone through bulletin boards, forums and the popular press. Newspapers and new agencies constantly report on the latest pharma-medical finding, or news regarding food safety and security concerns. We live in an age where information is so readily available to everyone that the task of finding credible and reputable data can be difficult at times. Providing sound evidenced based research is where a peer-reviewed journal can provide clarity. [...

  14. MUSC Environmental Biosciences Program First Quarter Report May - June, 2002

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr

    2002-07-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC02-98CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific program, employing a range of research initiatives to identify, study and resolve environmental health risk issues. These initiatives are consistent with the Medical University's role as a comprehensive state-supported health sciences institution and the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable the Medical University to be a national resource for the scientific investigation of environmental health issues. EBP's success in convening worldwide scientific expertise is due in part to the inherent credibility the Medical University brings to the process of addressing these complex issues.

  15. Annual report and summaries of FY 1993 activities: Division of Energy Biosciences

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    The mission of the Energy Biosciences program is to generate fundamental information about plants and non-health related microorganisms that will constitute the base for new biotechnologies as well as supply information to improve usages of such organisms in their current form. The collective aims are totally consistent with the Department of Energy`s objectives of developing alternate energy sources, replacements for otherwise fossil energy derived products and providing critical fundamental information for the preservation and restoration of environmental conditions affected by energy related activities. The EB program takes full advantage of its organizational locale in the Office of Basic Energy Sciences to directly interact with such disciplines as Materials Sciences, Chemistry, Engineering and Geosciences to promote cross-disciplinary research and planning activities. One of the major specific objectives of the EB program is to probe the enormous capabilities of the specified organisms to carry out biochemical conversions. The limitation to realization of entirely new products and processes via biotechnology is the lack of basic understanding of natural processes. Such knowledge will then afford the advantage of developing procedures to the benefit of people and their society in providing new products along with providing new employment possibilities. This document consists of abstracts of projects supported in FY 1993.

  16. Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

    Directory of Open Access Journals (Sweden)

    Carol Kilkenny

    2014-02-01

    Full Text Available In the last decade the number of bioscience journals has increased enormously, with many filling specialised niches reflecting new disciplines and technologies. The emergence of open-access journals has revolutionised the publication process, maximising the availability of research data. Nevertheless, a wealth of evidence shows that across many areas, the reporting of biomedical research is often inadequate, leading to the view that even if the science is sound, in many cases the publications themselves are not “fit for purpose”, meaning that incomplete reporting of relevant information effectively renders many publications of limited value as instruments to inform policy or clinical and scientific practice [1–21]. A recent review of clinical research showed that there is considerable cumulative waste of financial resources at all stages of the research process, including as a result of publications that are unusable due to poor reporting [22]. It is unlikely that this issue is confined to clinical research [2–14,16–20].

  17. Reflective Writing as a Tool for Assessing Teamwork in Bioscience: Insights into Student Performance and Understanding of Teamwork

    Science.gov (United States)

    Mayne, Lynne

    2012-01-01

    To ensure a modern bioscience curriculum that responds to the current needs of stakeholders, there is a need to embed a range of generic capabilities that enables graduates to succeed in and contribute to a rapidly changing world, as well as building strong bioscience skills and knowledge. The curriculum must also prepare students for a rapidly…

  18. Design of an Integrated Team Project as Bachelor Thesis in Bioscience Engineering

    Science.gov (United States)

    Peeters, Marie-Christine; Londers, Elsje; Van der Hoeven, Wouter

    2014-01-01

    Following the decision at the KU Leuven to implement the educational concept of guided independent learning and to encourage students to participate in scientific research, the Faculty of Bioscience Engineering decided to introduce a bachelor thesis. Competencies, such as communication, scientific research and teamwork, need to be present in the…

  19. Reflective Practice: A Place in Enhancing Learning in the Undergraduate Bioscience Teaching Laboratory?

    Science.gov (United States)

    Parry, Damian; Walsh, Cathy; Larsen, Carl; Hogan, Joanne

    2012-01-01

    Bioscience employers demand graduates with better practical competence. It is our supposition that, although undesirable, student learning is assessment driven and this is leading students to simply go through the motions in the practical setting (whether field work or laboratory based). In this intervention a Critical Incident Report was…

  20. Call for Papers--Bioscience Methods (ISSN 1925-1920)

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Bioscience Methods (BM) (ISSN 1925-1920) is a new launched, open access and peer-revi- ewed journal that dedicates to publish the original research papers involving in innovative technologies and novel experimental arts within the fields ofbiosciences.

  1. Call for papers—Bioscience Methods(ISSN 1925-1920)

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Bioscience Methods(BM)(ISSN 1925-1920) is a new launched,open access and peer-reviewed journal that dedicates to publish the original research papers involving in innovative technologies and novel experimental arts within the fields ofbiosciences.

  2. Call for papers--Bioscience Methods (ISSN 1925-1920)

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Bioscience Methods (BM) (ISSN 1925-1920) is a new launched, open access and peer-reviewed journal that dedicates to publish the original research papers involving in innovative technologies and novel experimental arts within the fields ofbiosciences.

  3. Correlation of Serum Soluble Interleukin-7 Receptor and Anti-C1q Antibody in Patients with Systemic Lupus Erythematosus

    Directory of Open Access Journals (Sweden)

    Shuhong Chi

    2016-01-01

    Full Text Available Background. Serum concentrations of soluble interleukin-7 receptor (sIL-7R and anti-C1q antibody have recently been identified as unique serological markers for lupus nephritis (LN in patients with systemic lupus erythematosus (SLE. In this study, we evaluated the correlation of serum sIL-7R and anti-C1q in SLE patients. Methods. Sera from 134 patients with SLE and 84 healthy cohorts were tested for levels of sIL-7R and anti-C1q antibodies in terms of ELISA. Correlations of the sIL-7R and anti-C1q autoantibodies were evaluated. Results. The serum concentrations of sIL-7R and anti-C1q antibodies were significantly higher in SLE patients and LN patients in comparison with healthy individuals/controls and SLE patients with non-LN, respectively. In addition, both sIL-7R and anti-C1q concentrations were found to significantly correlate with the SLE disease activity as evaluated by SLEDAI scores. Interestingly, the serum sIL-7R concentration was strongly correlated with the level of anti-C1q antibodies (r=0.2871, p=0.0008 but not statistically correlated with other serological markers, including the anti-dsDNA and complements C3 and C4 concentrations in SLE patients. Conclusion. Both serum sIL-7R and anti-C1q antibodies were strongly associated with disease activity and LN in SLE patients, suggesting that they may be reliable serological markers for identification of SLE patients with active diseases and LN.

  4. Division of energy biosciences: Annual report and summaries of FY 1995 activities

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    The mission of the Division of Energy Biosciences is to support research that advances the fundamental knowledge necessary for the future development of biotechnologies related to the Department of Energy`s mission. The departmental civilian objectives include effective and efficient energy production, energy conservation, environmental restoration, and waste management. The Energy Biosciences program emphasizes research in the microbiological and plant sciences, as these understudied areas offer numerous scientific opportunities to dramatically influence environmentally sensible energy production and conservation. The research supported is focused on the basic mechanisms affecting plant productivity, conversion of biomass and other organic materials into fuels and chemicals by microbial systems, and the ability of biological systems to replace energy-intensive or pollutant-producing processes. The Division also addresses the increasing number of new opportunities arising at the interface of biology with other basic energy-related sciences such as biosynthesis of novel materials and the influence of soil organisms on geological processes.

  5. Highlights of the 3rd International Conference on High Pressure Bioscience and Biotechnology

    Directory of Open Access Journals (Sweden)

    J.A. Mignaco

    2005-08-01

    Full Text Available The 3rd International Conference on High Pressure Bioscience and Biotechnology was held in the city of Rio de Janeiro from September 27 to September 30, 2004. The meeting, promoted by the International Association of High Pressure Bioscience and Biotechnology (IAHPBB, congregated top scientists and researchers from all over the world. In common, they shared the use of hydrostatic pressure for research, technical development, or industrial applications. The meeting consisted of invited lectures, contributed papers and a well-attended poster session. Very exciting discussions were held inside and outside the sessions, and the goals of discussing state-of-the-art data and establishing working collaborations and co-operations were fully attained.

  6. The molecular biology revolution and the rise of bioscience megacentres in North America and Europe

    OpenAIRE

    Philip Cooke

    2004-01-01

    This paper focuses on 'triple helix' effects in biosciences. Scientific change can have profound socioeconomic effects. The molecular biology revolution tilted pharmaceuticals production away from its fine chemistry path dependence into microbiology and biotechnology. The key to any triple helix effects has thus shifted to universities and spinouts buttressed with burgeoning public funding, leaving 'big pharma' increasingly playing the role of licenser and marketer of bought-in therapeutic tr...

  7. Assessment of Collaboration and Interoperability in an Information Management System to Support Bioscience Research

    OpenAIRE

    Myneni, Sahiti; Patel, Vimla L.

    2009-01-01

    Biomedical researchers often have to work on massive, detailed, and heterogeneous datasets that raise new challenges of information management. This study reports an investigation into the nature of the problems faced by the researchers in two bioscience test laboratories when dealing with their data management applications. Data were collected using ethnographic observations, questionnaires, and semi-structured interviews. The major problems identified in working with these systems were rela...

  8. Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research †

    OpenAIRE

    Carol Kilkenny; Browne, William J.; Cuthill, Innes C; Michael Emerson; Altman, Douglas G.

    2014-01-01

    In the last decade the number of bioscience journals has increased enormously, with many filling specialised niches reflecting new disciplines and technologies. The emergence of open-access journals has revolutionised the publication process, maximising the availability of research data. Nevertheless, a wealth of evidence shows that across many areas, the reporting of biomedical research is often inadequate, leading to the view that even if the science is sound, in many cases the publications...

  9. The scientific assessment of combined effects of risk factors: different approaches in experimental biosciences and epidemiology

    OpenAIRE

    Boedeker, Wolfgang; Backhaus, Thomas

    2010-01-01

    Abstract The analysis of combined effects of substances or risk factors has been a subject to science for more than a century. With different goals, combined effect analysis was addressed in almost all experimental biosciences. The major theoretical foundation can be traced back to two distinct origins. First, to the work by the pharmacologist Loewe on the concept of concentration additivity and second to the biometrician Bliss and the concept of independent action. In the search f...

  10. Preclinical imaging: an essential ally in modern biosciences.

    Science.gov (United States)

    Cunha, Lídia; Horvath, Ildiko; Ferreira, Sara; Lemos, Joana; Costa, Pedro; Vieira, Domingos; Veres, Dániel S; Szigeti, Krisztián; Summavielle, Teresa; Máthé, Domokos; Metello, Luís F

    2014-04-01

    Translational research is changing the practice of modern medicine and the way in which health problems are approached and solved. The use of small-animal models in basic and preclinical sciences is a major keystone for these kinds of research and development strategies, representing a bridge between discoveries at the molecular level and clinical implementation in diagnostics and/or therapeutics. The development of high-resolution in vivo imaging technologies provides a unique opportunity for studying disease in real time, in a quantitative way, at the molecular level, along with the ability to repeatedly and non-invasively monitor disease progression or response to treatment. The greatest advantages of preclinical imaging techniques include the reduction of biological variability and the opportunity to acquire, in continuity, an impressive amount of unique information (without interfering with the biological process under study) in distinct forms, repeated or modulated as needed, along with the substantial reduction in the number of animals required for a particular study, fully complying with 3R (Replacement, Reduction and Refinement) policies. The most suitable modalities for small-animal in vivo imaging applications are based on nuclear medicine techniques (essentially, positron emission tomography [PET] and single photon emission computed tomography [SPECT]), optical imaging (OI), computed tomography (CT), magnetic resonance imaging (MRI), magnetic resonance spectroscopy imaging (MRSI), and ultrasound. Each modality has intrinsic advantages and limitations. More recently, aiming to overcome the inherent limitations of each imaging modality, multimodality devices designed to provide complementary information upon the pathophysiological process under study have gained popularity. The combination of high-resolution modalities, like micro-CT or micro-MRI, with highly sensitive techniques providing functional information, such as micro-PET or micro-SPECT, will

  11. Division of Energy Biosciences annual report and summaries of FY 1996 activities

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-04-01

    The mission of the Division of Energy Biosciences is to support research that advances the fundamental knowledge necessary for the future development of biotechnologies related to the Department of Energy`s mission. The departmental civilian objectives include effective and efficient energy production, energy conservation, environmental restoration, and waste management. The Energy Biosciences program emphasizes research in the microbiological and plant sciences, as these understudied areas offer numerous scientific opportunities to dramatically influence environmentally sensible energy production and conservation. The research supported is focused on the basic mechanism affecting plant productivity, conversion of biomass and other organic materials into fuels and chemicals by microbial systems, and the ability of biological systems to replace energy-intensive or pollutant-producing processes. The Division also addresses the increasing number of new opportunities arising at the interface of biology with other basic energy-related sciences such as biosynthesis of novel materials and the influence of soil organisms on geological processes. This report gives summaries on 225 projects on photosynthesis, membrane or ion transport, plant metabolism and biosynthesis, carbohydrate metabolism lipid metabolism, plant growth and development, plant genetic regulation and genetic mechanisms, plant cell wall development, lignin-polysaccharide breakdown, nitrogen fixation and plant-microbial symbiosis, mechanism for plant adaptation, fermentative microbial metabolism, one and two carbon microbial metabolism, extremophilic microbes, microbial respiration, nutrition and metal metabolism, and materials biosynthesis.

  12. Ontologies and standards in bioscience research: for machine or for human

    Directory of Open Access Journals (Sweden)

    HuaiyuMi

    2011-02-01

    Full Text Available Ontologies and standards are very important parts of today’s bioscience research. With the rapid increase of biological knowledge, they provide mechanisms to better store and represent data in a controlled and structured way, so that scientists can share the data, and utilize a wide variety of software and tools to manage and analyze the data. Most of these standards are initially designed for computers to access large amounts of data that are difficult for human biologists to handle, and it is important to keep in mind that ultimately biologists are going to produce and interpret the data. While ontologies and standards must follow strict semantic rules that may not be familiar to biologists, effort must be spent to lower the learning barrier by involving biologists in the process of development, and by providing software and tool support. A standard will not succeed without support from the wider bioscience research community. Thus, it is crucial that these standards be designed not only for machines to read, but also to be scientifically accurate and intuitive to human biologists.

  13. A Case Report of Blood Group Discrepancy because of Anti A1 with Clinical Significance and Anti C

    OpenAIRE

    Babadivand, P; Selseleh, M (Monavar); Ebrahimy, P.; J. Esmaeili

    2012-01-01

    Background and objectives: ABO phenotyping is one of theessential tests in Immunohematology. Incompatible blood grouptransfusion leads to acute hemolysis reactions and other seriouscomplications. Anti A1 is a cold Antibody with no clinicalsignificance, but if it is reacted at 37˚c can be clinically significant,which will be happened rarely. At the present, we report a Case withanti A1 having clinical significance and Anti C.Material and methods: The patient was suffering from Paroxysmalnoctur...

  14. On the outside looking in: redefining the role of analytical chemistry in the biosciences.

    Science.gov (United States)

    Hare, Dominic J; New, Elizabeth J

    2016-07-12

    Biomedical research has moved on from the study of the structure of organs, cells and organelles. Today, the key questions that must be addressed to understand the body in health and disease are related to fundamental biochemistry: the distribution and speciation of chemicals, the regulation of chemical reactions, and the control of chemical environments. To see advances in this field, it is essential for analytical chemists to actively engage in this process, from beginning to end. In this Feature Article, we review the progress that has been made towards gaining an understanding of the chemistry of the body, while commenting on the intrinsic disconnect between new innovations in the field of analytical chemistry and practical application within the biosciences. We identify the challenges that prevent chemists from making a greater impact in this field, and highlight key steps for moving forward. PMID:26898242

  15. Assessment of Collaboration and Interoperability in an Information Management System to Support Bioscience Research

    Science.gov (United States)

    Myneni, Sahiti; Patel, Vimla L.

    2009-01-01

    Biomedical researchers often have to work on massive, detailed, and heterogeneous datasets that raise new challenges of information management. This study reports an investigation into the nature of the problems faced by the researchers in two bioscience test laboratories when dealing with their data management applications. Data were collected using ethnographic observations, questionnaires, and semi-structured interviews. The major problems identified in working with these systems were related to data organization, publications, and collaboration. The interoperability standards were analyzed using a C4I framework at the level of connection, communication, consolidation, and collaboration. Such an analysis was found to be useful in judging the capabilities of data management systems at different levels of technological competency. While collaboration and system interoperability are the “must have” attributes of these biomedical scientific laboratory information management applications, usability and human interoperability are the other design concerns that must also be addressed for easy use and implementation. PMID:20351900

  16. Scientific Reports of Plasma Medicine and its Mechanism for Therapy in Plasma Bioscience Research Center

    Science.gov (United States)

    Choi, Eun Ha

    2015-09-01

    Scientific reports of plasma medicine and its basic mechanism for therapy will be introduced, especially, performed in Plasma Bioscience Research Center, Korea. We have investigated enhanced anticancer effect of monocytes and macrophages activated by nonthermal plasma which act as immune-modulator on these immune cells. Further, we investigated the action of the nanosecond pulsed plasma activated media (NPPAM) on the lung cancer cells and its DNA oxidation pathway. We observed OD induced apoptosis on melanocytes G361 cancer cells through DNA damage signaling cascade. We also studied DNA oxidation by extracting DNA from treated cancer cell and analyzed the effects of OD/OH/D2O2/H2O2 on protein modification and oxidation. Additionally, we attempted molecular docking approaches to check the action of D2O2 on the apoptosis related genes.

  17. Googling your genes: personal genomics and the discourse of citizen bioscience in the network age

    Directory of Open Access Journals (Sweden)

    Marina Levina

    2010-03-01

    Full Text Available In this essay, I argue that the rise of personal genomics is technologically, economically, and most importantly, discursively tied to the rise of network subjectivity, an imperative of which is an understanding of self as always already a subject in the network. I illustrate how personal genomics takes full advantage of social media technology and network subjectivity to advertise a new way of doing research that emphasizes collaboration between researchers and its members. Sharing one’s genetic information is considered to be an act of citizenship, precisely because it is good for the network. Here members are encouraged to think of themselves as dividuals, or nodes, in the network and their actions acquire value based on that imperative. Therefore, citizen bioscience is intricately tied, both in discourse and practices, to the growth of the network in the age of new media.

  18. A preliminary exploration of the advanced molecular bio-sciences research center

    International Nuclear Information System (INIS)

    Low dose and low dose rate radiation effects on lifespan, pathological changes, hemopoiesis and cytokine production in mice have been investigated in our laboratory. In the intermediate period of the investigation, an expert committee on radiation biology was organized. The purposes of the committee were to assess previous studies and advise on a future research plan for the Advanced Molecular Bio-Sciences Research Center (AMBIC). The committee emphasized the necessity of molecular research in radiation biology, and proposed the following five subjects: 1) molecular carcinogenesis by low dose radiation; 2) radiation effects on the immune and hemopoietic systems; 3) molecular mechanisms of hereditary effect; 4) noncancer diseases of low dose radiation, and 5) cellular mechanisms by low dose radiation. (author)

  19. Effect of A-Level Subject Choice and Entry Tariff on Final Degree and Level 1 Performance in Biosciences

    Science.gov (United States)

    King, Nicola C.; Aves, Stephen J.

    2012-01-01

    Following the publication of the higher education white paper increasing entry tariff and widening participation have become even more important issues for universities. This report examines the relationship between entry tariff and undergraduate achievement in Biosciences at the University of Exeter. We show that, whilst there is a significant…

  20. Production of Doctorates in the Biosciences, 1975-1980: An Experimental Forecast. Higher Education Panel Reports, No. 34.

    Science.gov (United States)

    Atelsek, Frank J.; Gomberg, Irene L.

    A survey was undertaken in 1976 to obtain short-term estimates of doctorate production directly from the heads of the science departments involved. These biosciences departments were surveyed in the 235 member institutions of the Higher Education Panel that grant doctorates: anatomy, biochemistry, biology, biometry/biostatistics/biomathematics,…

  1. Francis Crick, cross-worlds influencer: A narrative model to historicize big bioscience

    Science.gov (United States)

    Aicardi, Christine

    2016-01-01

    The essay is an empirical case study of famed British scientist Francis Crick. Viewing him as a ‘cross-worlds influencer’ who was moreover dedicated to a cause, I have tried to understand how these two characteristics influenced the trajectory of his long career and how they shaped his contributions to the diverse research fields in which he was active, and concluded that these characteristics reconfigure Crick's career into a coherent whole. First, I identify a major thread running through Crick's career: helping organise ‘un-disciplined’ new research fields, and show that his successive choices were not serendipitous but motivated by what he construed as a crusade against ‘vitalism’: anti-vitalism was a defining driver of his career. I then examine how Crick put his skills as a crossworlds influencer to the service of his cause, by helping organise his chosen fields of intervention. I argue that his activities as a cross-worlds influencer were an integral part of his way of ‘doing science’ and that his contributions to science, neuroscience in particular, should be re-evaluated in this light. This leads me to advance a possible strategy for historians to investigate big bioscience fields. Following Abir-Am, I propose to trace their genealogies back to the fluctuating semi-institutional gatherings and the institutional structures that sustained them. My research on Crick supports the view that such studies can bring insights into the question of why the contours of contemporary big bioscience endeavours have come to be shaped the way they are. Further, the essay provides a heuristic device for approaching these enquiries: ‘follow the cross-worlds influencers’ who worked to build and organise these semi-institutional gatherings and institutional structures. PMID:26383132

  2. Effects of anti-C23 (nucleolin) antibody on transcription of ribosomal DNA in Chironomus salivary gland cells

    Energy Technology Data Exchange (ETDEWEB)

    Egyhazi, E.; Pigon, A. (Karolinska Institutet, Stockholm (Sweden)); Chang, Jinhong; Ghaffari, S.H.; Dreesen, T.D.; Wellman, S.E.; Case, S.T.; Olson, M.O.J. (Univ. of Mississippi Medical Center, Jackson (USA))

    1988-10-01

    Protein C23 (also called nucleolin or 100-kDa nucleolar protein) is a major nucleolar phosphoprotein involved in ribosome biogenesis. To determine the effects of protein C23 on preribosomal RNA (pre-rRNA) synthesis anti-C23 antiserum was microinjected into nuclei of Chironomus tentans salivary glands. Transcription was measured by incubation of the glands with {sup 32}P-labeled RNA precursors followed by microdissection of nucleoli, RNA extraction, and electrophoretic analyses. Injection of the anti-C23 antibody caused a 2- to 3.5-fold stimulation of {sup 32}P incorporation into 38 S pre-rRNA. No stimulation was observed in salivary glands injected with preimmune serum or antiserum preabsorbed with protein C23. The stimulatory effect was selective for pre-rRNA as indicated by the lack of stimulation of {sup 32}P incorporation into extranucleolar RNA. Injection of the antiserum produced little or no effect on pre-RNA processing as measured by the relative amounts of {sup 32}P-labeled intermediate cleavage products of pre-rRNA in stimulated versus control glands. These results suggest that protein C23 not only is involved in ribosome assembly but also plays a role in regulating the transcription of the preribosomal RNA.

  3. Effects of anti-C23 (nucleolin) antibody on transcription of ribosomal DNA in Chironomus salivary gland cells

    International Nuclear Information System (INIS)

    Protein C23 (also called nucleolin or 100-kDa nucleolar protein) is a major nucleolar phosphoprotein involved in ribosome biogenesis. To determine the effects of protein C23 on preribosomal RNA (pre-rRNA) synthesis anti-C23 antiserum was microinjected into nuclei of Chironomus tentans salivary glands. Transcription was measured by incubation of the glands with 32P-labeled RNA precursors followed by microdissection of nucleoli, RNA extraction, and electrophoretic analyses. Injection of the anti-C23 antibody caused a 2- to 3.5-fold stimulation of 32P incorporation into 38 S pre-rRNA. No stimulation was observed in salivary glands injected with preimmune serum or antiserum preabsorbed with protein C23. The stimulatory effect was selective for pre-rRNA as indicated by the lack of stimulation of 32P incorporation into extranucleolar RNA. Injection of the antiserum produced little or no effect on pre-RNA processing as measured by the relative amounts of 32P-labeled intermediate cleavage products of pre-rRNA in stimulated versus control glands. These results suggest that protein C23 not only is involved in ribosome assembly but also plays a role in regulating the transcription of the preribosomal RNA

  4. Division of Energy Biosciences annual report and summaries of FY 1991 activities

    Energy Technology Data Exchange (ETDEWEB)

    1991-09-01

    As a component of the Department of Energy, the Energy Biosciences (EB) program of the Office of Basic Energy Sciences supports long-term research aimed at addressing energy-related problems utilizing biological systems. There are three main components of the EB program. The first, Primary Biological Energy Conversion, concentrates on research on plant and microbial photosynthesis, but also deals with plant growth control, stress reactions, and interaction with pathogens. The second, Bioconversion of Products, concentrates on utilization of the products of primary energy conversion. Specific examples include biosynthesis of potential fuels or chemicals, biodegradation of lignocellulose into potentially useful compounds, plant/microbe symbiosis, microbial methanogenesis and fermentation. The third main component of the EB program involves providing the basic research infrastructure to support future discoveries. The emphasis here is on investigation of basic genetic mechanisms, both in novel systems and extensively studied systems such as maize; development of critical databases, techniques, and instrumentation; and support of training in areas that are important but underpopulated. Brief descriptions of currently supported research projects are provided. 186 refs., 1 tab (MHB)

  5. Division of Energy Biosciences annual report and summaries of FY 1991 activities

    International Nuclear Information System (INIS)

    As a component of the Department of Energy, the Energy Biosciences (EB) program of the Office of Basic Energy Sciences supports long-term research aimed at addressing energy-related problems utilizing biological systems. There are three main components of the EB program. The first, Primary Biological Energy Conversion, concentrates on research on plant and microbial photosynthesis, but also deals with plant growth control, stress reactions, and interaction with pathogens. The second, Bioconversion of Products, concentrates on utilization of the products of primary energy conversion. Specific examples include biosynthesis of potential fuels or chemicals, biodegradation of lignocellulose into potentially useful compounds, plant/microbe symbiosis, microbial methanogenesis and fermentation. The third main component of the EB program involves providing the basic research infrastructure to support future discoveries. The emphasis here is on investigation of basic genetic mechanisms, both in novel systems and extensively studied systems such as maize; development of critical databases, techniques, and instrumentation; and support of training in areas that are important but underpopulated. Brief descriptions of currently supported research projects are provided. 186 refs., 1 tab

  6. Challenges and opportunities for early-career Teaching-Focussed academics in the biosciences [v2; ref status: indexed, http://f1000r.es/5c2

    Directory of Open Access Journals (Sweden)

    Katharine Hubbard

    2015-04-01

    Full Text Available Twenty-seven percent of academics in UK Higher Education (HE are in Teaching-Focussed positions, making major contributions to undergraduate programmes in an era of high student expectations when it comes to teaching quality. However, institutional support for Teaching-Focussed academics is often limited, both in terms of peer networking and opportunities for career development. As four early-career stage Teaching-Focussed academics working in a variety of institutions, we explore what motivated our choices to make teaching our primary academic activity, and the challenges that we have faced in doing so. In addition to highlighting the need for universities to fully recognise the achievements of teaching staff, we discuss the role that the various biosciences learned societies have in supporting Teaching-Focussed academics. We identify that there is a need for the learned societies to come together and pool their expertise in this area. The fragmented nature of the Teaching-Focussed academic community means that clear sources of national support are needed in order to best enable the next generation of bioscience educators to reach their full potential.

  7. A business case for on-site generation: The BD biosciences pharmingen project

    Energy Technology Data Exchange (ETDEWEB)

    Firestone, Ryan; Creighton, Charles; Bailey, Owen; Marnay, Chris; Stadler, Michael

    2003-09-01

    Deregulation is haltingly changing the United States electricity markets. The resulting uncertainty and/or rising energy costs can be hedged by generating electricity on-site and other benefits, such as use of otherwise wasted heat, can be captured. The Public Utility Regulatory Policy Act (PURPA) of 1978 first invited relatively small-scale generators ({ge} 1 MW) into the electricity market. The advent of efficient and reliable small scale and renewable equipment has spurred an industry that has, in recent years, made even smaller (business scale) electricity generation an economically viable option for some consumers. On-site energy capture and/or conversion, known as distributed energy resources (DER), offers consumers many benefits, such as economic savings and price predictability, improved reliability, control over power quality, and emissions reductions. Despite these benefits, DER adoption can be a daunting move to a customer accustomed to simply paying a monthly utility bill. San Diego is in many ways an attractive location for DER development: It has high electricity prices typical of California and a moderate climate i.e. energy loads are consistent throughout the year. Additionally, the price shock to San Diego Gas and Electric (SDG&E) customers during the summer of 2000 has interested many in alternatives to electricity price vulnerability. This report examines the business case for DER at the San Diego biotechnology supply company, BD Biosciences Pharmingen, which considered DER for a building with 200-300 kW base-load, much of which accommodates the refrigerators required to maintain chemicals. Because of the Mediterranean climate of the San Diego area and the high rate of air changes required due to on-site use of chemicals, modest space heating is required throughout the year. Employees work in the building during normal weekday business hours, and daily peak loads are typically about 500 kW.

  8. SBBN 2010: 7. Congress of the Brazilian Society of Nuclear Biosciences. Radiations in biosciences: advances and trends; SBBN 2010: 7. Congresso da Sociedade Brasileira de Biociencias Nucleares. Radiacoes em biociencias: avancos e perspectivas

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    Advance and new perspectives related to the use of ionizing and no ionizing radiations in nuclear biosciences are presented. Multidisciplinary approach, including radiopharmacy, radioprotection and dosimetry, cytogenetic, biosafety, radioecology, environmental toxicology are studied. Topics of Nuclear medicine, radiotherapy and image diagnosis, such as computerized tomography, PET scan, phantoms, biomedical radiography, are reported. Use of radioisotopes, evaluation of radiation dose rates, radiation dose distribution, radiation monitoring is considered. Environmental impact of radiation are also in human beings, animals and for several purposes are analyzed. (MAC)

  9. A tale of three next generation sequencing platforms: comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq sequencers

    Directory of Open Access Journals (Sweden)

    Quail Michael A

    2012-07-01

    Full Text Available Abstract Background Next generation sequencing (NGS technology has revolutionized genomic and genetic research. The pace of change in this area is rapid with three major new sequencing platforms having been released in 2011: Ion Torrent’s PGM, Pacific Biosciences’ RS and the Illumina MiSeq. Here we compare the results obtained with those platforms to the performance of the Illumina HiSeq, the current market leader. In order to compare these platforms, and get sufficient coverage depth to allow meaningful analysis, we have sequenced a set of 4 microbial genomes with mean GC content ranging from 19.3 to 67.7%. Together, these represent a comprehensive range of genome content. Here we report our analysis of that sequence data in terms of coverage distribution, bias, GC distribution, variant detection and accuracy. Results Sequence generated by Ion Torrent, MiSeq and Pacific Biosciences technologies displays near perfect coverage behaviour on GC-rich, neutral and moderately AT-rich genomes, but a profound bias was observed upon sequencing the extremely AT-rich genome of Plasmodium falciparum on the PGM, resulting in no coverage for approximately 30% of the genome. We analysed the ability to call variants from each platform and found that we could call slightly more variants from Ion Torrent data compared to MiSeq data, but at the expense of a higher false positive rate. Variant calling from Pacific Biosciences data was possible but higher coverage depth was required. Context specific errors were observed in both PGM and MiSeq data, but not in that from the Pacific Biosciences platform. Conclusions All three fast turnaround sequencers evaluated here were able to generate usable sequence. However there are key differences between the quality of that data and the applications it will support.

  10. Sheared-type G(anti).C(syn) base-pair: a unique d(GXC) loop closure motif.

    Science.gov (United States)

    Chin, Ko-Hsin; Chou, Shan-Ho

    2003-05-30

    Stable DNA loop structures closed by a novel G.C base-pair have been determined for the single-residue d(GXC) loops (X=A, T, G or C) in low-salt solution by high-resolution nuclear magnetic resonance (NMR) techniques. The closing G.C base-pair in these loops is not of the canonical Watson-Crick type, but adopts instead a unique sheared-type (trans Watson-Crick/sugar-edge) pairing, like those occurring in the sheared mismatched G.A or A.C base-pair, to draw the two opposite strands together. The cytidine residue in the closing base-pair is transformed into the rare syn domain to form two H-bonds with the guanine base and to prevent the steric clash between the G 2NH(2) and the C H-5 protons. Besides, the sugar pucker of the syn cytidine is still located in the regular C2'-endo domain, unlike the C3'-endo domain adopted for the pyrimidines of the out-of-alternation left-handed Z-DNA structure. The facile formation of the compact d(GXC) loops closed by a unique sheared-type G(anti).C(syn) base-pair demonstrates the great potential of the single-stranded d(GXC) triplet repeats to fold into stable hairpins. PMID:12758081

  11. Acute hemolytic transfusion reactions due to multiple alloantibodies including anti-E, anti-c and anti-Jkb.

    Science.gov (United States)

    Park, Tae Sung; Kim, Ki Uk; Jeong, Woo Jin; Kim, Hyung Hoi; Chang, Chulhun L; Chung, Joo Seop; Cho, Goon Jae; Lee, Eun Yup; Son, Han Chul

    2003-12-01

    We report a case of two consecutive episodes of acute hemolytic transfusion reactions (HTRs) due to multiple alloantibodies in a 34-yr-old man who suffered from avascular necrosis of left femoral head. He received five units of packed red blood cells (RBCs) during surgery. Then the transfusion of packed RBCs was required nine days after the surgery because of the unexplained drop in hemoglobin level. The transfusion of the first two units resulted in fever and brown-colored urine, but he received the transfusion of another packed RBCs the next day. He experienced even more severe symptoms during the transfusion of the first unit. We performed antibody screening test, and it showed positive results. Multiple alloantibodies including anti-E, anti-c and anti-Jkb were detected by antibody identification study. Acute HTRs due to multiple alloantibodies were diagnosed, and the supportive cares were done for 6 days. We suggest the antibody screening test should be included in the panel of pretransfusion tests for safer transfusion, and it is particularly mandatory for the patients with multiple transfusions, pregnant women, and preoperative patients. PMID:14676451

  12. Bioculture System: Expanding ISS Space Bioscience Capabilities for Fundamental Stem Cell Research and Commercial Applications

    Science.gov (United States)

    Blaber, Elizabeth; Dvorochkin, Natalya; Almeida, Eduardo; Fitzpatrick, Garret; Ellingson, Lance; Mitchell, Sarah; Yang, Anthony; Kosnik, Cristine; Rayl, Nicole; Cannon, Tom; Austin, Edward; Sato, Kevin

    With the recent call by the 2011 Decadal Report and the 2010 Space Biosciences Roadmap for the International Space Station (ISS) to be used as a National Laboratory for scientific research, there is now a need for new laboratory instruments on ISS to enable such research to occur. The Bioculture System supports the extended culturing of multiple cell types and microbiological specimens. It consists of a docking station that carries ten independent incubation units or ‘Cassettes’. Each Cassette contains a cooling chamber (5(°) C) for temperature sensitive solutions and samples, or long duration fluids and sample storage, as well as an incubation chamber (ambient up to 42(°) C). Each Cassette houses an independent fluidics system comprised of a biochamber, medical-grade fluid tubing, medium warming module, oxygenation module, fluid pump, and sixteen solenoid valves for automated biochamber injections of sampling. The Bioculture System provides the user with the ability to select the incubation temperature, fluid flow rate and automated biochamber sampling or injection events for each separate Cassette. Furthermore, the ISS crew can access the biochamber, media bag, and accessory bags on-orbit using the Microgravity Science Glovebox. The Bioculture System also permits initiation of cultures, subculturing, injection of compounds, and removal of samples for on-orbit processing using ISS facilities. The Bioculture System therefore provides a unique opportunity for the study of stem cells and other cell types in space. The first validation flight of the Bioculture System will be conducted on SpaceX5, consisting of 8 Cassettes and lasting for 30-37 days. During this flight we plan to culture two different mammalian cell types in bioreactors: a mouse osteocytic-like cell line, and human induced pluripotent stem cell (iPS)-derived cardiomyocytes. Specifically, the osteocytic line will enable the study of a type of cell that has been flown on the Bioculture System

  13. The binding affinity of a soluble TCR-Fc fusion protein is significantly improved by crosslinkage with an anti-C{beta} antibody

    Energy Technology Data Exchange (ETDEWEB)

    Ozawa, Tatsuhiko; Horii, Masae; Kobayashi, Eiji [Department of Immunology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194 (Japan); Jin, Aishun [Department of Immunology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194 (Japan); Department of Immunology, College of Basic Medical Sciences, Harbin Medical University, 157 Baojian Road, Nangang District, Harbin 150081 (China); Kishi, Hiroyuki, E-mail: immkishi@med.u-toyama.ac.jp [Department of Immunology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194 (Japan); Muraguchi, Atsushi [Department of Immunology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194 (Japan)

    2012-06-01

    Highlights: Black-Right-Pointing-Pointer A novel soluble TCR composed of TCR V and C regions with Ig Fc region is generated. Black-Right-Pointing-Pointer TCR-Fc protein immobilized by an anti-C{beta} antibody bound to a p/MHC tetramer. Black-Right-Pointing-Pointer Binding affinity of TCR-Fc was markedly increased by binding with anti-C{beta} antibody. -- Abstract: The identification and cloning of tumor antigen-specific T cell receptors (TCRs) and the production of the soluble form of the TCR (sTCR) contributed to the development of diagnostic and therapeutic tools for cancer. Recently, several groups have reported the development of technologies for the production of sTCRs. The native sTCR has a very low binding affinity for the antigenic peptide/MHC (p/MHC) complex. In this study, we established a technology to produce high affinity, functional sTCRs. We generated a novel sTCR-Fc fusion protein composed of the TCR V and C regions of the TCR linked to the immunoglobulin (Ig) Fc region. A Western blot analysis revealed that the molecular weight of the fusion protein was approximately 60 kDa under reducing conditions and approximately 100-200 kDa under non-reducing conditions. ELISAs using various antibodies showed that the structure of each domain of the TCR-Fc protein was intact. The TCR-Fc protein immobilized by an anti-C{beta} antibody effectively bound to a p/MHC tetramer. An SPR analysis showed that the TCR-Fc protein had a low binding affinity (KD; 1.1 Multiplication-Sign 10{sup -5} M) to the p/MHC monomer. Interestingly, when the TCR-Fc protein was pre-incubated with an anti-C{beta} antibody, its binding affinity for p/MHC increased by 5-fold (2.2 Multiplication-Sign 10{sup -6} M). We demonstrated a novel method for constructing a functional soluble TCR using the Ig Fc region and showed that the binding affinity of the functional sTCR-Fc was markedly increased by an anti-C{beta} antibody, which is probably due to the stabilization of the V

  14. Anticorpos anti-C1q, anticromatina/nucleossomo e anti-dsDNA em pacientes com lúpus eritematoso sistêmico juvenil Anti-C1q, anti-chromatin/nucleosome, and anti-dsDNA antibodies in juvenile systemic lupus erythematosus patients

    OpenAIRE

    Adriana Almeida de Jesus; Lucia Maria Arruda Campos; Bernadete Lourdes Liphaus; Magda Carneiro-Sampaio; Cristóvão Luis Pitangueira Mangueira; Eliane Aparecida Rosseto; Clovis Artur Almeida da Silva; Morton Scheinberg

    2012-01-01

    OBJETIVO: Avaliar a presença de anticorpos anti-C1q, anticromatina/nucleossomo e anti-DNA de duplo filamento (dsDNA) em pacientes com lúpus eritematoso sistêmico juvenil (LESJ) e controles. MÉTODOS: Foram analisados 67 pacientes com LESJ e 34 controles saudáveis para presença de anticorpos anti-C1q, anticromatina/nucleossomo e anti-dsDNA pelo método ELISA. Os níveis de C1q foram avaliados por imunodifusão radial. RESULTADOS: Na época, a média de idade era similar entre os pacientes com LESJ e...

  15. Severe hydrops in the infant of a Rhesus D-positive mother due to anti-c antibodies diagnosed antenatally: a case report

    Directory of Open Access Journals (Sweden)

    Sharma Jai

    2010-02-01

    Full Text Available Abstract Introduction Rhesus haemolytic disease of the newborn is a prototype of maternal isoimmunisation and fetal haemolytic disease. There are other rare blood group antigens capable of causing alloimmunisation and haemolytic disease such as c, C, E, Kell and Duffy. In India, after the confirmation of a newborn's blood group, antibodies are screened only if the mother is Rehsus D-negative negative and the father is Rhesus D-positive. Hydrops in Rhesus positive women are investigated along the lines of non-immune hydrops. Case presentation We report the case of a patient from India where irregular antibodies were requested for an O-positive 26-year-old mother in order to investigate fetal hydrops. Anti-c antibody was revealed and the fetus was treated successfully with compatible O negative and c negative intrauterine blood transfusions. The baby was treated postnatally with double volume exchange transfusion with the same compatible blood, and was discharged 30 days after birth. Conclusion We highlight the importance of conducting irregular antibody screening for women with significant obstetric history and fetal hydrops. This could assist in diagnosing and successfully treating the fetus with appropriate antigen negative cross-matched compatible blood. We note, however, that anti-c immunoglobulin is not yet readily available.

  16. Programmable bio-nano-chip system: a flexible point-of-care platform for bioscience and clinical measurements.

    Science.gov (United States)

    McRae, Michael P; Simmons, Glennon W; Wong, Jorge; Shadfan, Basil; Gopalkrishnan, Sanjiv; Christodoulides, Nicolaos; McDevitt, John T

    2015-10-21

    The development of integrated instrumentation for universal bioassay systems serves as a key goal for the lab-on-a-chip community. The programmable bio-nano-chip (p-BNC) system is a versatile multiplexed and multiclass chemical- and bio-sensing system for bioscience and clinical measurements. The system is comprised of two main components, a disposable cartridge and a portable analyzer. The customizable single-use plastic cartridges, which now can be manufactured in high volumes using injection molding, are designed for analytical performance, ease of use, reproducibility, and low cost. These labcard devices implement high surface area nano-structured biomarker capture elements that enable high performance signaling and are index-matched to real-world biological specimens. This detection modality, along with the convenience of on-chip fluid storage in blisters and self-contained waste, represents a standard process to digitize biological signatures at the point-of-care. A companion portable analyzer prototype has been developed to integrate fluid motivation, optical detection, and automated data analysis, and it serves as the human interface for complete assay automation. In this report, we provide a systems-level perspective of the p-BNC universal biosensing platform with an emphasis on flow control, device integration, and automation. To demonstrate the flexibility of the p-BNC, we distinguish diseased and non-case patients across three significant disease applications: prostate cancer, ovarian cancer, and acute myocardial infarction. Progress towards developing a rapid 7 minute myoglobin assay is presented using the fully automated p-BNC system. PMID:26308851

  17. Tutorials in mathematical biosciences

    CERN Document Server

    2008-01-01

    The book offers an easy introduction to fast growing research areas in evolution of species, population genetics, ecological models, and population dynamics. The first two chapters review the concept and methodologies of phylogenetic trees; computational schemes and illustrations are given, including applications such as tracing the origin of SARS and influenza. The third chapter introduces the reader to ecological models, including predator-prey models. This chapter includes and introduction to reaction-diffusion equations, which are used to analyze the ecological models. The next chapter reviews a broad range of ongoing research in population dynamics, including evolution of dispersal models; it also features interesting mathematical theorems and lists open problems. The final chapter deals with gene frequencies under the action of migration and selection. The book is addressed to readers at the level of grad students and researchers. A background in PDEs is provided.

  18. Magnetic nanoparticles and biosciences

    Czech Academy of Sciences Publication Activity Database

    Šafařík, Ivo; Šafaříková, Miroslava

    New Delhi : Indian Society of Magnetic Fluid Research, 2003 - (Lal, K.), s. 171-173 [International Workshop on Recent Advances in Nanotechnology of Magnetic Fluids. New Delhi (IN), 22.01.2003-24.01.2003] R&D Projects: GA ČR(CZ) GA203/03/1070; GA MŠk(CZ) OC 523.80 Institutional research plan: CEZ:AV0Z6087904 Keywords : nanotechnology * magnetic fluid Subject RIV: JI - Composite Materials

  19. Measurement of the forward-backward asymmetry in Z→b anti b and Z→c anti c decays with leptons

    International Nuclear Information System (INIS)

    The sample of hadronic Z decays collected by the Aleph detector at Lep in the years 1991-1995 is analysed in order to measure the forward-backward asymmetry in Z→b anti b and Z→c anti c events and the B0- anti B0 average mixing parameter anti χ. Quark charges are tagged by the charges of electrons and muons produced in b and c semileptonic decays. Multivariate analyses are used to separate the event flavours and b→l/b→c→l processes. The b and c quark asymmetries are measured simultaneously; the average mixing parameter and the pole asymmetries are determined to be anti χ=0.1196± 0.0049(stat.)+0.0043-0.0050(syst.),A(0,b)FB=0.0998±0.0040(sta t.)±0.0017(syst.), A0,cFB=0.0732±0.0053(stat.)±0.0037(syst.). These asymmetries, combined with the Aleph measurements of the b asymmetry using inclusive b hadron decays and of the c asymmetry using reconstructed D mesons, correspond to a value of the effective electroweak mixing angle of sin2θeffW=0.23188±0.00046. (orig.)

  20. A specific assay for quantification of human C4c by use of an anti-C4c monoclonal antibody

    DEFF Research Database (Denmark)

    Pilely, Katrine; Skjoedt, Mikkel-Ole; Nielsen, Christian; Andersen, Thomas Emil; Åbom, Anne; Vitved, Lars; Koch, Claus; Skjødt, Karsten; Palarasah, Yaseelan

    2014-01-01

    The increasing evidence of the implication of the complement system in the pathogenesis of several diseases has emphasized the need for the development of specific and valid assays, optimized for quantitative detection of complement activation in vivo. In the present study, we have developed a...... and samples from factor I deficient patients. The specificity of the mAb was further evaluated by immunoprecipitation techniques and by analysis of eluted fragments of C4 after immunoaffinity chromatography. The anti-C4c mAb was confirmed to be C4c specific, as it showed no cross-reactivity with...... native (un-cleaved) C4, C4b, iC4b, or C4d. Also, no reaction was observed with C4 fragments in factor I deficient plasma or serum samples. We established and validated a sandwich ELISA based on this C4c specific antibody. The normal range of C4c in EDTA/futhan plasma collected from 100 Danish blood...

  1. Conventional versus single-ladder-splitting contributions to double parton scattering production of two quarkonia, two Higgs bosons and c anti cc anti c

    International Nuclear Information System (INIS)

    The double parton distributions (dPDF), both conventional and those corresponding to parton splitting, are calculated and compared for different two-parton combinations. The conventional and splitting dPDFs have very similar shape in x1 and x2. We make a first quantitative evaluation of the single-ladder-splitting contribution to double parton scattering (DPS) production of two S- or P-wave quarkonia, two Higgs bosons and c anti cc anti c. The ratio of the single-ladder-splitting to conventional contributions is discussed as a function of centre-of-mass energy, mass of the produced system and other kinematical variables. Using a simple model for the dependence of the conventional two-parton distribution on transverse parton separation (Gaussian and independent of xi and scales), we find that the 2v1 contribution is as big as the 2v2 contribution discussed in recent years in the literature. This means that the phenomenological analyses of σeff including only the conventional DPS mechanism have to be revised including explicitly the single-ladder-splitting contributions discussed here. The differential distributions in rapidity and transverse momenta calculated for conventional and single-ladder-splitting DPS processes are however very similar which causes their experimental separation to be rather difficult, if not impossible. The direct consequence of the existence of the two components (conventional and splitting) is the energy and process dependence of the empirical parameter σeff. This is illustrated in our paper for the considered processes.

  2. Implementation of ML Using Naïve Bayes Algorithm for Identifying Disease-Treatment Relation in Bio-Science Text

    Directory of Open Access Journals (Sweden)

    T.F. Michael Raj

    2013-01-01

    Full Text Available In recent years many successful machine learning applications have been developed, ranging from datamining programs to information-filtering systems that learn users' reading preferences. At the same time, there have been important advances in the theory and algorithms that can be used identify the diseases and treatment relations in a Bio-Science text. Imagine a computer learns from medical records which treatments are most effective for new diseases. Having the machine learning concept behind we have proposed a Machine Learning (ML approach based on Naïve Bayes (NB algorithm to improve the automatic disease identification in the medical field. And also we have improved text classification by using an integrated model.

  3. Development of a dedicated beam forming system for material and bioscience research with high intensity, small field electron beam of LILLYPUT 3 accelerator at Wroclaw Technology Park

    CERN Document Server

    Adrich, Przemysław; Wilk, Piotr; Chorowski, Maciej; Poliński, Jarosław; Bogdan, Piotr

    2016-01-01

    The primary use of the LILLYPUT 3 accelerator at the Nondestructive Testing Laboratory at Wroclaw Technology Park is X-ray radiography for nondestructive testing, including R&D of novel techniques for industrial and medical imaging. The scope of possible applications could be greatly extended by providing a system for irradiation with electron beam. The purpose of this work was to design such a system, especially for high dose rate, small field irradiations under cryogenic conditions for material and bioscience research. In this work, two possible solutions, based either on beam scanning or scattering and collimation, were studied and compared. It was found that under existing conditions efficiency of both systems would be comparable. The latter one was adopted due to its simplicity and much lower cost. The system design was optimized by means of detailed Monte Carlo modeling. The system is being currently fabricated at National Centre for Nuclear Research in \\'Swierk.

  4. The integration of the "spirituality in medicine" curriculum into the osteopathic communication curriculum at Kansas City University of Medicine and Biosciences.

    Science.gov (United States)

    Talley, Jan A; Magie, Richard

    2014-01-01

    With grant funding from the John Templeton Spirituality and Medicine Curricular Award to the George Washington Institute for Spirituality and Health, faculty at Kansas City University of Medicine and Biosciences (KCUMB) developed the "Spirituality in Medicine" curriculum. In developing the curriculum, faculty took into consideration competencies required by the Association of American Medical Colleges and qualitative results from surveys of medical school applicants and enrolled students. Strategies for curriculum delivery included lectures, panel discussions, role-playing, and training in the use of a spirituality assessment tool. A majority of the 250 students who received the training in 2010-2011 were able to demonstrate the following competencies: (1) being sensitive to patients' spiritual and cultural needs, (2) assessing patients' and their own spiritual needs, (3) appropriately using chaplain services for patient care, and (4) understanding the effects of health disparities and ethical issues on patient care. Challenges to implementation included a reduction in chaplain availability due to the economic downturn, a lack of student exposure to direct patient care during shadowing, too little religious diversity among chaplains, and changes in assignment schedules. New competencies required by the National Board of Osteopathic Medical Examiners overlap with and help ensure sustainability of the Spirituality in Medicine curriculum. KCUMB leaders have incorporated the use of the spirituality assessment tool into other parts of the curriculum and into service experiences, and they have introduced a new elective in palliative care. Synergistic efforts by faculty leaders for this initiative were critical to the implementation of this curriculum. PMID:24280841

  5. Development of a methylation marker set for forensic age estimation using analysis of public methylation data and the Agena Bioscience EpiTYPER system.

    Science.gov (United States)

    Freire-Aradas, A; Phillips, C; Mosquera-Miguel, A; Girón-Santamaría, L; Gómez-Tato, A; Casares de Cal, M; Álvarez-Dios, J; Ansede-Bermejo, J; Torres-Español, M; Schneider, P M; Pośpiech, E; Branicki, W; Carracedo, Á; Lareu, M V

    2016-09-01

    Individual age estimation has the potential to provide key information that could enhance and extend DNA intelligence tools. Following predictive tests for externally visible characteristics developed in recent years, prediction of age could guide police investigations and improve the assessment of age-related phenotype expression patterns such as hair colour changes and early onset of male pattern baldness. DNA methylation at CpG positions has emerged as the most promising DNA tests to ascertain the individual age of the donor of a biological contact trace. Although different methodologies are available to detect DNA methylation, EpiTYPER technology (Agena Bioscience, formerly Sequenom) provides useful characteristics that can be applied as a discovery tool in localized regions of the genome. In our study, a total of twenty-two candidate genomic regions, selected from the assessment of publically available data from the Illumina HumanMethylation 450 BeadChip, had a total of 177 CpG sites with informative methylation patterns that were subsequently investigated in detail. From the methylation analyses made, a novel age prediction model based on a multivariate quantile regression analysis was built using the seven highest age-correlated loci of ELOVL2, ASPA, PDE4C, FHL2, CCDC102B, C1orf132 and chr16:85395429. The detected methylation levels in these loci provide a median absolute age prediction error of ±3.07years and a percentage of prediction error relative to the age of 6.3%. We report the predictive performance of the developed model using cross validation of a carefully age-graded training set of 725 European individuals and a test set of 52 monozygotic twin pairs. The multivariate quantile regression age predictor, using the CpG sites selected in this study, has been placed in the open-access Snipper forensic classification website. PMID:27337627

  6. On limit and limit setting.

    Science.gov (United States)

    Gorney, J E

    1994-01-01

    This article investigates the role of limit and limit setting within the psychoanalytic situation. Limit is understood to be a boundary between self and others, established as an interactional dimension of experience. Disorders of limit are here understood within the context of Winnicott's conception of the "anti-social tendency." Limit setting is proposed as a necessary and authentic response to the patient's acting out via holding and empathic responsiveness, viewed here as a form of boundary delineation. It is proposed that the patient attempts to repair his or her boundary problem through a seeking of secure limits within the analyst. The setting of secure and appropriate limits must arise from a working through of the analyst's own countertransference response to the patient. It is critical that this response be evoked by, and arise from, the immediate therapeutic interaction so that the patient can experience limit setting as simultaneously personal and authentic. PMID:7972580

  7. Quench limits

    International Nuclear Information System (INIS)

    With thirteen beam induced quenches and numerous Machine Development tests, the current knowledge of LHC magnets quench limits still contains a lot of unknowns. Various approaches to determine the quench limits are reviewed and results of the tests are presented. Attempt to reconstruct a coherent picture emerging from these results is taken. The available methods of computation of the quench levels are presented together with dedicated particle shower simulations which are necessary to understand the tests. The future experiments, needed to reach better understanding of quench limits as well as limits for the machine operation are investigated. The possible strategies to set BLM (Beam Loss Monitor) thresholds are discussed. (author)

  8. Limited Neutrality

    DEFF Research Database (Denmark)

    Nielsen, Morten Ebbe Juul

    2006-01-01

    Article Concerning the prospect of a kind of limited neutrality in place of the standard liberal egalitarian "neutrality of justification."......Article Concerning the prospect of a kind of limited neutrality in place of the standard liberal egalitarian "neutrality of justification."...

  9. Dose limits

    International Nuclear Information System (INIS)

    The dose limit is defined to be the level of harmfulness which must not be exceeded, so that an activity can be exercised in a regular manner without running a risk unacceptable to man and the society. The paper examines the effects of radiation categorised into stochastic and non-stochastic. Dose limits for workers and the public are discussed

  10. The interfacial bioscience grand challenge.

    Energy Technology Data Exchange (ETDEWEB)

    Lane, Pamela; Stevens, Mark Jackson; Jacobsen, Richard B.; Hong, Joohee; Ayson, Marites J.; Crozier, Paul Stewart; Wood, Nichole L.; Schoeniger, Joseph S.; Kruppa, Gary Hermann; Sale, Kenneth L.; Young, Malin M.; Faulon, Jean-Loup Michel; Burns, Alan Richard; Evans, Kervin O.; Novak, Petr

    2004-03-01

    This report is broken down into the following 3 sections: (1) Chemical Cross-linking and Mass Spectrometry Applied to Determination of Protein Structure and Dynamics; (2) Computational Modeling of Membrane Protein Structure and Dynamics; and (3) Studies of Toxin-Membrane Interactions using Single Molecule Biophysical Methods.

  11. Limiting Skepticism

    DEFF Research Database (Denmark)

    Hendricks, Vincent Fella; Symons, John

    2011-01-01

    Skeptics argue that the acquisition of knowledge is impossible given the standing possibility of error. We present the limiting convergence strategy for responding to skepticism and discuss the relationship between conceivable error and an agent’s knowledge in the limit. We argue that the skeptic...... must demonstrate that agents are operating with a bad method or are in an epistemically cursed world. Such demonstration involves a significant step beyond conceivability and commits the skeptic to potentially convergent inquiry...

  12. Treatment with anti-C5aR mAb leads to early-onset clinical and mechanistic effects in the murine delayed-type hypersensitivity arthritis model

    DEFF Research Database (Denmark)

    Atkinson, Sara Marie; Nansen, Anneline; Usher, Pernille A.;

    2015-01-01

    Blockade of the complement cascade at the C5a/C5a receptor (C5aR)-axis is believed to be an attractive treatment avenue in rheumatoid arthritis (RA). However, the effects of such interventions during the early phases of arthritis remain to be clarified. In this study we use the murine delayed-typ...... arthritic disease development in a DTHA model strengthening the rationale of C5aR-blockade as a treatment strategy for RA, especially during the early stages of arthritis flare.......-type hypersensitivity arthritis (DTHA) model to study the very early effects of a blocking, non-depleting anti-C5aR mAb on joint inflammation with treatment synchronised with disease onset, an approach not previously described. The DTHA model is a single-paw inflammatory arthritis model characterised by synchronised...... and rapid disease onset driven by T-cells, immune complexes and neutrophils. We show that a reduction in paw swelling, bone erosion, cartilage destruction, synovitis and new bone formation is apparent as little as 60 h after administration of a single dose of a blocking, non-depleting anti-mouse C5a...

  13. Rethinking and Reconstruction on Animal Welfare in Experiments of Bioscience%生命科学实验中动物福利问题的反思与重构——基于生态哲学视角

    Institute of Scientific and Technical Information of China (English)

    朱玉芳

    2011-01-01

    针对目前生命科学实验中学生排斥使用实验动物的现象,反思并分析了过度关注动物福利的原因,并在解读生态哲学思想的基础上重构了实验中动物福利问题,旨在为高校的生命科学实验的顺利进行提供启示和借鉴.%At present,according to the phenomenon that students reject experimenting on animal in experiments of bioscience.the article reflects on and analyses the reasons for paying excessive attention to animal welfare,and on the basis of interpreting ecological philosophy,it rebuild the view of animal welfare in experiment,aiming at providing enlightenment and experience for carrying on biological science experiment successfully in college.

  14. Bioética, violência e desigualdade: as biociências e a constituição do biopoder Bioethics, violence and inequality: the biosciences and the conquest of biopower

    Directory of Open Access Journals (Sweden)

    Hélder Boska de Moraes Sarmento

    2008-12-01

    Full Text Available A sociedade contemporânea está atravessada por contradições e paradoxos, dentre os quais vale destacar a relação entre a alta tecnologia e, a pior situação humana, a miséria. Resultado das escolhas éticas e políticas desta era tecnológica, vive-se em situações de fronteira, nas quais as biociências desempenham papel central, tanto no volume de conhecimentos gerados, como na utilização de seus resultados, que, sem controle social, ampliam desigualdades. O objetivo deste artigo é demonstrar o quanto as biociências articulam-se com o desenvolvimento científico dos países inovadores de tecnologia, criando uma nova relação de poder, violento e desigual para os que apenas a consomem, denominado de biopoder. Daí a necessidade de uma bioética crítica capaz de empreender reflexões sobre os procedimentos técnicos, os fundamentos da atividade científica, sua aplicabilidade e relação com o mercado, oportunizando uma 'ponte' na tomada de decisões para que a própria ciência não se torne um obstáculo à democracia.Contemporary society is rife with contradictions and paradoxes, among which stand out the relationship between high technology and the worst human situation, poverty. The result of ethical and political choices of this technological era, we experience frontier situations, in which the biosciences play a central role, both in the volume of knowledge generated, as well as in the use of their results which, without social control, broaden inequalities. The objective of this article is to demonstrate the degree to which the biosciences are articulated with the scientific development of the countries that innovate technologies, creating a new relationship of power, which is violent and unequal for those who only consume, denominated biopower. This creates a need for a critical bioethics that is capable of reflecting on the technical procedures, the bases of scientific activity and their applicability and relation with

  15. HOME Income Limits

    Data.gov (United States)

    Department of Housing and Urban Development — HOME Income Limits are calculated using the same methodology that HUD uses for calculating the income limits for the Section 8 program. These limits are based on...

  16. Postdoctoral Training in Bioscience: Allocation and Outcomes.

    Science.gov (United States)

    McGinnis, Robert; And Others

    1982-01-01

    Studied the careers of 557 biochemists to investigate: (1) the effects of predoctoral research productivity on postdoctoral training opportunities; (2) how the location of postdoctoral training affects the prestige of subsequent jobs; and (3) the effects of postdoctoral training on publication rates. (GC)

  17. Factors Affecting Bioscience Students' Academic Achievement

    Science.gov (United States)

    Rytkonen, Henna; Parpala, Anna; Lindblom-Ylanne, Sari; Virtanen, Viivi; Postareff, Liisa

    2012-01-01

    The examination of academic progression has become an essential tool for measuring the effectiveness of educational systems. Research concerning the relationship between student learning and how they progress in their studies, however remains scarce. The aim of this study is two-fold: Firstly, the study aims to analyse first-year bioscience…

  18. Passive immitance limiters

    OpenAIRE

    Filinyuk N. A.; Lischinskaya L. B.; Chekhmestruk R. Yu.

    2015-01-01

    The paper presents quadripole R, L, C immittance limiters, in which output immittance to the certain value depends on the input immittance. A classification of immittance limiters is given. Basic parameters are considered: low and high levels of output immittance limiters; low and high values of input immittance, corresponding to low and high levels of limitation, accordingly; range of possible values of output immittance; steepness of immittance limiters; time of wearing-out (or delay); high...

  19. Limits to adaptation

    Science.gov (United States)

    Dow, Kirstin; Berkhout, Frans; Preston, Benjamin L.; Klein, Richard J. T.; Midgley, Guy; Shaw, M. Rebecca

    2013-04-01

    An actor-centered, risk-based approach to defining limits to social adaptation provides a useful analytic framing for identifying and anticipating these limits and informing debates over society's responses to climate change.

  20. Interval graph limits

    CERN Document Server

    Diaconis, Persi; Janson, Svante

    2011-01-01

    We work out the graph limit theory for dense interval graphs. The theory developed departs from the usual description of a graph limit as a symmetric function $W(x,y)$ on the unit square, with $x$ and $y$ uniform on the interval $(0,1)$. Instead, we fix a $W$ and change the underlying distribution of the coordinates $x$ and $y$. We find choices such that our limits are continuous. Connections to random interval graphs are given, including some examples. We also show a continuity result for the chromatic number and clique number of interval graphs. Some results on uniqueness of the limit description are given for general graph limits.

  1. Passive immitance limiters

    Directory of Open Access Journals (Sweden)

    Filinyuk N. A.

    2015-06-01

    Full Text Available The paper presents quadripole R, L, C immittance limiters, in which output immittance to the certain value depends on the input immittance. A classification of immittance limiters is given. Basic parameters are considered: low and high levels of output immittance limiters; low and high values of input immittance, corresponding to low and high levels of limitation, accordingly; range of possible values of output immittance; steepness of immittance limiters; time of wearing-out (or delay; high and low cutoff frequencies; central working frequency; frequency band; relative range of working frequencies; non-linearity coefficient. The authors have designed passive R-, L-, C-limiters with possibility of limitation from above and from below. The influence of the input parasitic immittances on the immittance transfer characteristic is evaluated. In most cases parasite immittance does not influence the considered devices, including R-limiters «from above» with the input quality factor of QR(Linp=0,1…0,2 and L-limiters «from above» with high-quality input circuits with QL(Rinp>2. The analysis also shows that high-qualitiy circuits with QN(RinpN>3 should be used in C-limiters with input parasitic immittances, while at parasitic immittance of the limiting element low-quality circuits with QN(RiN>0,2 should be selected.

  2. The JET belt limiter

    International Nuclear Information System (INIS)

    A limiter with an effective area in contact with the plasma of about 16 m2 is presently being manufactured for installation in 1987. This belt limiter consists of two toroidal rings located above and below the equatorial plane of the vacuum vessel. Each of the two rings comprises a structure with water cooling pipes and fins welded to the pipes. The limiter material in contact with the plasma (graphite or beryllium) is inserted between fins in the form of tiles. The belt limiter is designed to handle up to 40 MW of total power at flux densities of 3 - 5 MW/m2 for 10 s and to permit rapid exchange of different limiter materials. The design and manufacture of the belt limiter and the results of thermomechanical analysis for different edge properties, power levels and shot repetition rates, are reported. (author)

  3. The jet belt limiter

    International Nuclear Information System (INIS)

    A limiter with an effective area in contact with the plasma of about 16 m/sup 2/ is presently being manufactured for installation in 1987. This belt limiter consists of two toroidal rings located above and below the equatorial plane of the vacuum vessel. Each of the two rings comprises a structure with water cooling pipes and fins welded to the pipes. The limiter material in contact with the plasma (graphite or beryllium) is inserted between fins in the form of tiles. The belt limiter is designed to handle up to 40 MW of total power at flux densities of 3 - 5 MW/m/sup 2/ for 10 s and to permit rapid exchange of different limiter materials. This paper describes the design and manufacture of the belt limiter and the results of thermomechanical analysis for different edge properties, power levels and shot repetition rates

  4. Limit loads in nozzles

    International Nuclear Information System (INIS)

    The static method for the evaluation of the limit loads of a perfectly elasto-plastic structure is presented. Using the static theorem of Limit Analysis and the Finite Element Method, a lower bound for the colapso load can be obtained through a linear programming problem. This formulation if then applied to symmetrically loaded shells of revolution and some numerical results of limit loads in nozzles are also presented. (Author)

  5. Reactor limit control system

    International Nuclear Information System (INIS)

    The very extensive use of limitations in the operational field between protection system and closed-loop controls is an important feature of German understanding of operational safety. The design of limitations is based on very large activities in the computational field but mostly on the high level of the plant-wide own commissioning experience of a turnkey contractor. Limitations combine intelligence features of closed-loop controls with the high availability of protection systems. (orig.)

  6. Limit analysis via creep

    International Nuclear Information System (INIS)

    In this paper it is presented a variational method for the limit analysis of an ideal plastic solid. This method has been denominated as Modified Secundary Creep and enables to find the collapse loads through a minimization of a functional and a limit process. Given an ideal plastic material it is shown how to determinate the associated secundary creep constitutive equation. Finally, as an application, it is found the limit load in an pressurized von Mises rigid plastic sphere. (Author)

  7. Friction Generated Limit Cycles

    OpenAIRE

    Ohlsson, Henrik; Åström, Karl Johan

    2001-01-01

    This paper treats limit cycles caused by friction. The goal has been to explain phenomena that have been observed experimentally in mechatronic systems. Experiments have shown that oscillations of qualitatively different types can be obtained simply by changing controller specifications. Stiction is important in some cases but not in others. Necessary conditions for limit cycle are given for the case where stiction is important. Conditions for local stability of the limit cycles are also pres...

  8. Dose limits for astronauts

    Science.gov (United States)

    Sinclair, W. K.

    2000-01-01

    Radiation exposures to individuals in space can greatly exceed natural radiation exposure on Earth and possibly normal occupational radiation exposures as well. Consequently, procedures limiting exposures would be necessary. Limitations were proposed by the Radiobiological Advisory Panel of the National Academy of Sciences/National Research Council in 1970. This panel recommended short-term limits to avoid deterministic effects and a single career limit (of 4 Sv) based on a doubling of the cancer risk in men aged 35 to 55. Later, when risk estimates for cancer had increased and were recognized to be age and sex dependent, the NCRP, in Report No. 98 in 1989, recommended a range of career limits based on age and sex from 1 to 4 Sv. NCRP is again in the process of revising recommendations for astronaut exposure, partly because risk estimates have increased further and partly to recognize trends in limiting radiation exposure occupationally on the ground. The result of these considerations is likely to be similar short-term limits for deterministic effects but modified career limits.

  9. Numerical Limit Analysis:

    DEFF Research Database (Denmark)

    Damkilde, Lars

    2007-01-01

    Limit State analysis has a long history and many prominent researchers have contributed. The theoretical foundation is based on the upper- and lower-bound theorems which give a very comprehensive and elegant formulation on complicated physical problems. In the pre-computer age Limit State analysis...

  10. Limits to Inclusion

    Science.gov (United States)

    Hansen, Janne Hedegaard

    2012-01-01

    In this article, I will argue that a theoretical identification of the limit to inclusion is needed in the conceptual identification of inclusion. On the one hand, inclusion is formulated as a vision that is, in principle, limitless. On the other hand, there seems to be an agreement that inclusion has a limit in the pedagogical practice. However,…

  11. Universal Limits on Computation

    CERN Document Server

    Krauss, L M

    2004-01-01

    The physical limits to computation have been under active scrutiny over the past decade or two, as theoretical investigations of the possible impact of quantum mechanical processes on computing have begun to make contact with realizable experimental configurations. We demonstrate here that the observed acceleration of the Universe can produce a universal limit on the total amount of information that can be stored and processed in the future, putting an ultimate limit on future technology for any civilization, including a time-limit on Moore's Law. The limits we derive are stringent, and include the possibilities that the computing performed is either distributed or local. A careful consideration of the effect of horizons on information processing is necessary for this analysis, which suggests that the total amount of information that can be processed by any observer is significantly less than the Hawking-Beckenstein entropy associated with the existence of an event horizon in an accelerating universe.

  12. Modeling Complex Time Limits

    Directory of Open Access Journals (Sweden)

    Oleg Svatos

    2013-01-01

    Full Text Available In this paper we analyze complexity of time limits we can find especially in regulated processes of public administration. First we review the most popular process modeling languages. There is defined an example scenario based on the current Czech legislature which is then captured in discussed process modeling languages. Analysis shows that the contemporary process modeling languages support capturing of the time limit only partially. This causes troubles to analysts and unnecessary complexity of the models. Upon unsatisfying results of the contemporary process modeling languages we analyze the complexity of the time limits in greater detail and outline lifecycles of a time limit using the multiple dynamic generalizations pattern. As an alternative to the popular process modeling languages there is presented PSD process modeling language, which supports the defined lifecycles of a time limit natively and therefore allows keeping the models simple and easy to understand.

  13. Tokamak pump limiters

    International Nuclear Information System (INIS)

    Recent experiments with a scoop limiter without active internal pumping have been carried out in the PDX tokamak with up to 6MW of auxiliary neutral beam heating. Experiments have also been done with a rotating head pump limiter in the PLT tokamak in conjunction with RF plasma heating. Extensive experiments have been done in the ISX-B tokamak and first experiments have been completed with the ALT-I limiter in TEXTOR. The pump limiter modules in these latter two machines have internal getter pumping. Experiments in ISX-B are with ohmic and auxiliary neutral beam heating. The results in ISX-B and TEXTOR show that active density control and particle removal is achieved with pump limiters. In ISX-B, the boundary layer (or scape-off layer) plasma partially screens the core plasma from gas injection. In both ISX-B and TEXTOR, the pressure internal to the module scales linearly with plasma density but in ISX-B, with neutral beam injection, a nonlinear increase is observed at the highest densities studied. Plasma plugging is the suspected cause. Results from PDX suggest that a region may exist in which core plasma energy confinement improves using a pump limiter during neutral beam injection. Asymmetric radial profiles and an increased edge electron temperature are observed in discharges with improved confinement. The injection of small amounts of neon into ISX-B has more clearly shown an improved electron core energy confinement during neutral beam injection. While carried out with a regular limiter, this Z-mode of operation is ideal for use with pump limiters and should be a way to achieve energy confinement times similar to values for H-mode tokamak plasmas. The implication of all these results for the design of a reactor pump limiter is described

  14. Interval Graph Limits

    OpenAIRE

    Diaconis, Persi; Holmes, Susan; Janson, Svante

    2012-01-01

    We work out the graph limit theory for dense interval graphs. The theory developed departs from the usual description of a graph limit as a symmetric function $W(x,y)$ on the unit square, with $x$ and $y$ uniform on the interval $(0,1)$. Instead, we fix a $W$ and change the underlying distribution of the coordinates $x$ and $y$. We find choices such that our limits are continuous. Connections to random interval graphs are given, including some examples. We also show a continuity result for th...

  15. Limit experiments of GARCH

    CERN Document Server

    Buchmann, Boris; 10.3150/10-BEJ328

    2012-01-01

    GARCH is one of the most prominent nonlinear time series models, both widely applied and thoroughly studied. Recently, it has been shown that the COGARCH model (which was introduced a few years ago by Kl\\"{u}ppelberg, Lindner and Maller) and Nelson's diffusion limit are the only functional continuous-time limits of GARCH in distribution. In contrast to Nelson's diffusion limit, COGARCH reproduces most of the stylized facts of financial time series. Since it has been proven that Nelson's diffusion is not asymptotically equivalent to GARCH in deficiency, in the present paper, we investigate the relation between GARCH and COGARCH in Le Cam's framework of statistical equivalence. We show that GARCH converges generically to COGARCH, even in deficiency, provided that the volatility processes are observed. Hence, from a theoretical point of view, COGARCH can indeed be considered as a continuous-time equivalent to GARCH. Otherwise, when the observations are incomplete, GARCH still has a limiting experiment, which we ...

  16. HUD Program Income Limits

    Data.gov (United States)

    Department of Housing and Urban Development — Income limits used to determine the income eligibility of applicants for assistance under three programs authorized by the National Housing Act. These programs are...

  17. Limited Income and Resources

    Data.gov (United States)

    U.S. Department of Health & Human Services — Information for those with limited income and resources (those who may qualify for or already have the Low Income Subsidy to lower their prescription drug coverage...

  18. Limited Denial of Participation

    Data.gov (United States)

    Department of Housing and Urban Development — A Limited Denial of Participation (LDP) is an action taken by a HUD Field Office or the Deputy Assistant Secretary for Single Family (DASSF) or Multifamily (DASMF)...

  19. SIS - Annual Catch Limit

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Annual Catch Limit (ACL) dataset within the Species Information System (SIS) contains information and data related to management reference points and catch data.

  20. HOME Rent Limits

    Data.gov (United States)

    Department of Housing and Urban Development — In accordance with 24 CFR Part 92.252, HUD provides maximum HOME rent limits. The maximum HOME rents are the lesser of: The fair market rent for existing housing...

  1. Coagulation with limited aggregations

    CERN Document Server

    Bertoin, Jean

    2012-01-01

    Smoluchowski's coagulation equations can be used as elementary mathematical models for the formation of polymers. We review here some recent contributions on a variation of this model in which the number of aggregations for each atom is a priori limited. Macroscopic results in the deterministic setting can be explained at the microscopic level by considering a version of stochastic coalescence with limited aggregations, which can be related to the so-called random configuration model of random graph theory.

  2. Limits for Life

    Science.gov (United States)

    Marion, Giles M.; Kargel, Jeffrey S.

    The current mantra of astrobiology is “Follow the Water.” Where there is water, there may be life. The FREZCHEM model can determine the presence or absence of water down to the eutectic temperature, below which only solid phases are thermodynamically stable. Salinity, the desiccation potential, and acidity are other potentially life-limiting factors that are calculated by FREZCHEM. In Chapter 4, we discuss potential life-limiting factors such as temperature, salinity, acidity, desiccation, radiation, pressure, and time.

  3. Limited Liability Company

    OpenAIRE

    Jarolímková, Vendula

    2010-01-01

    Limited liability company is today the most common legal form of business entities. This is mainly due to its simple establishment together with a low capital requirements. Preconditions of a foundation of a limited liability company require an establishment of the company, optaining a business license, a pay off of capital to the extent specified by the founding documents and laws, the acting on behalf of the company before its birth, and filling for incorporation into the trade register. Th...

  4. Haemolytic disease of the newborn due to anti-c

    OpenAIRE

    Abourazzak, Sana; Hajjaj, Safae; Hakima, Chekabab; Bouharrou, Abdelhak; Hida, Moustapha

    2009-01-01

    Anti-D isoimmunisation remains the most common cause of erythroblastosis fetalis. Whereas most clinically significant blood group sensitisations noted during pregnancy are still secondary to anti-D incompatibility, sensitisation to antigens other than D in the CDE system is not uncommon and can cause severe disease. The widespread use of Rh-D immune globulin has led to a relative increase in the importance of non-Rh-D isoimmunisation as a cause of haemolytic disease of the newborn. We report ...

  5. The quantum geometric limit

    CERN Document Server

    Lloyd, Seth

    2012-01-01

    This letter analyzes the limits that quantum mechanics imposes on the accuracy to which spacetime geometry can be measured. By applying the fundamental physical bounds to measurement accuracy to ensembles of clocks and signals moving in curved spacetime -- e.g., the global positioning system -- I derive a covariant version of the quantum geometric limit: the total number of ticks of clocks and clicks of detectors that can be contained in a four volume of spacetime of radius r and temporal extent t is less than or equal to rt/\\pi x_P t_P, where x_P, t_P are the Planck length and time. The quantum geometric limit bounds the number of events or `ops' that can take place in a four-volume of spacetime: each event is associated with a Planck-scale area. Conversely, I show that if each quantum event is associated with such an area, then Einstein's equations must hold. The quantum geometric limit is consistent with and complementary to the holographic bound which limits the number of bits that can exist within a spat...

  6. Fundamental Limits of Cooperation

    CERN Document Server

    Lozano, Angel; Andrews, Jeffrey G

    2012-01-01

    Cooperation is viewed as a key ingredient for interference management in wireless systems. This paper shows that cooperation has fundamental limitations. The main result is that even full cooperation between transmitters cannot in general change an interference-limited network to a noise-limited network. The key idea is that there exists a spectral efficiency upper bound that is independent of the transmit power. First, a spectral efficiency upper bound is established for systems that rely on pilot-assisted channel estimation; in this framework, cooperation is shown to be possible only within clusters of limited size, which are subject to out-of-cluster interference whose power scales with that of the in-cluster signals. Second, an upper bound is also shown to exist when cooperation is through noncoherent communication; thus, the spectral efficiency limitation is not a by-product of the reliance on pilot-assisted channel estimation. Consequently, existing literature that routinely assumes the high-power spect...

  7. Force Limit System

    Science.gov (United States)

    Pawlik, Ralph; Krause, David; Bremenour, Frank

    2011-01-01

    The Force Limit System (FLS) was developed to protect test specimens from inadvertent overload. The load limit value is fully adjustable by the operator and works independently of the test system control as a mechanical (non-electrical) device. When a test specimen is loaded via an electromechanical or hydraulic test system, a chance of an overload condition exists. An overload applied to a specimen could result in irreparable damage to the specimen and/or fixturing. The FLS restricts the maximum load that an actuator can apply to a test specimen. When testing limited-run test articles or using very expensive fixtures, the use of such a device is highly recommended. Test setups typically use electronic peak protection, which can be the source of overload due to malfunctioning components or the inability to react quickly enough to load spikes. The FLS works independently of the electronic overload protection.

  8. Quantum-Limited Spectroscopy

    CERN Document Server

    Truong, Gar-Wing; May, Eric F; Stace, Thomas M; Luiten, Andre N

    2015-01-01

    Spectroscopy has an illustrious history delivering serendipitous discoveries and providing a stringent testbed for new physical predictions, including applications from trace materials detection, to understanding the atmospheres of stars and planets, and even constraining cosmological models. Reaching fundamental-noise limits permits optimal extraction of spectroscopic information from an absorption measurement. Here we demonstrate a quantum-limited spectrometer that delivers high-precision measurements of the absorption lineshape. These measurements yield a ten-fold improvement in the accuracy of the excited-state (6P$_{1/2}$) hyperfine splitting in Cs, and reveals a breakdown in the well-known Voigt spectral profile. We develop a theoretical model that accounts for this breakdown, explaining the observations to within the shot-noise limit. Our model enables us to infer the thermal velocity-dispersion of the Cs vapour with an uncertainty of 35ppm within an hour. This allows us to determine a value for Boltzm...

  9. Limits on nonlinear electrodynamics

    Science.gov (United States)

    Fouché, M.; Battesti, R.; Rizzo, C.

    2016-05-01

    In this paper we set a framework in which experiments whose goal is to test QED predictions can be used in a more general way to test nonlinear electrodynamics (NLED) which contains low-energy QED as a special case. We review some of these experiments and we establish limits on the different free parameters by generalizing QED predictions in the framework of NLED. We finally discuss the implications of these limits on bound systems and isolated charged particles for which QED has been widely and successfully tested.

  10. Limitation of Auditors' Liability

    DEFF Research Database (Denmark)

    Werlauff, Erik; Foged-Ladefoged, Lise Kolding

    2014-01-01

    The article examines the question of whether rules on the limitation of auditors’ liability within the perspective of EU law are needed, and if so, which rules can provide an appropriate balance between the potential injured party’s interests and those of the auditing sector, including with respect...

  11. The Limits of Laughter.

    Science.gov (United States)

    Mindess, Harvey

    1983-01-01

    Three incidents which elucidate the limits of laughter are described. Most persons enjoy humor as comic relief, but when humor strikes a blow at something they hold dear, they find it very hard to laugh. People are upset by an irreverent attitude toward things they hold in esteem. (RM)

  12. Occupational dose equivalent limits

    International Nuclear Information System (INIS)

    This paper considers methods of limiting individual radiation risks by recognizing the variation of risk with age at exposure, taking into account both somatic and genetic risks and proposes a simple formula for controlling individual cumulative exposure and hence risk. (Author)

  13. Limitations on blanket performance

    International Nuclear Information System (INIS)

    The limitations on the performance of breeding blankets in a fusion power plant are evaluated. The breeding blankets will be key components of a plant and their limitations with regard to power density, thermal efficiency and lifetime could determine to a large degree the attractiveness of a power plant. The performance of two rather well known blanket concepts under development in the frame of the European Blanket Programme is assessed and their limitations are compared with more advanced (and more speculative) concepts. An important issue is the question of which material (structure, breeder, multiplier, coatings) will limit the performance and what improvement would be possible with a 'better' structural material. This evaluation is based on the premise that the performance of the power plant will be limited by the blankets (including first wall) and not by other components, e.g. divertors, or the plasma itself. However, the justness of this premise remains to be seen. It is shown that the different blanket concepts cover a large range of allowable power densities and achievable thermal efficiencies, and it is concluded that there is a high incentive to go for better performance in spite of possibly higher blanket cost. However, such high performance blankets are usually based on materials and technologies not yet developed and there is a rather high risk that the development could fail. Therefore, it is explained that a part of the development effort should be devoted to concepts where the materials and technologies are more or less in hand in order to ensure that blankets for a DEMO reactor can be developed and tested in a given time frame. (orig.)

  14. Auctions with Limited Commitment

    OpenAIRE

    Qingmin Liu; Konrad Mierendorff; Xianwen Shi

    2013-01-01

    We study auction design in the standard symmetric independent private values environment, where the seller lacks the commitment power to withhold an unsold object off the market. The seller has a single object and can conduct an infinite sequence of standard auctions with reserve prices to maximize her expected profit. In each period, the seller can commit to a reserve price for the current period but cannot commit to future reserve prices. We analyze the problem with limited commitment throu...

  15. Persuasion and Limited Communication

    OpenAIRE

    Itai Sher

    2008-01-01

    This paper studies optimal persuasion. A speaker must decide which arguments to present and a listener which arguments to accept. Communication is limited in that the arguments available to the speaker depend on her information. Optimality is assessed from the listener's perspective assuming that the listener can commit to a persuasion rule. I show that this seemingly simple scenario--introduced by Glazer and Rubinstein (2006)--is computationally intractable (formally, NP-hard). However under...

  16. Photovoltaic energy cost limit

    International Nuclear Information System (INIS)

    Referring to a photovoltaic system for grid connected applications, a parametric expression of kWh cost is derived. The limit of kWh cost is carried out extrapolating the values of cost components to their lowest figure. The reliability of the forecast is checked by disaggregating kWh cost in direct and indirect costs and by discussing the possible cost reduction of each component

  17. Limiting Similarity Revisited

    OpenAIRE

    Szabo, P; Meszena, G.

    2005-01-01

    We reinvestigate the validity of the limiting similarity principle via numerical simulations of the Lotka-Volterra model. A Gaussian competition kernel is employed to describe decreasing competition with increasing difference in a one-dimensional phenotype variable. The simulations are initiated by a large number of species, evenly distributed along the phenotype axis. Exceptionally, the Gaussian carrying capacity supports coexistence of all species, initially present. In case of any other, d...

  18. TFTR movable limiter installation

    International Nuclear Information System (INIS)

    The TFTR movable limiter is a poloidal limiter consisting of graphite tiles mounted on three blades with hinge connections supported by three independent actuators. The installed configuration is shown. The blades and actuators underwent mechanical, electrical and vacuum tests at the fabricator and at PPL prior to assembly with the TFTR vacuum vessel. During the preparation phase the installation crew removed the bus bar segments and air ducts that interfered with assembly and installed the support steel and the support table for the blade fixture. The actuators were assembled with the extension tubes and motor drives. The lower vertical actuator was rolled into the basement on carts, then pulled into position by a cable through the vacuum vessel. The upper vertical actuator was installed next by lowering into position from above. The three blades (with most of the graphite tiles installed), the cover plate, the horizontal actuator and water and instrumentation feed-throughs were mounted on an air cushion installation fixture, which was then lowered onto the support table. The assembly was floated into position with hand adjustment to engage the roller assemblies with the limiter bridges and the guide pins into the vacuum vessel. The cover plate was then bolted onto the vacuum vessel and the remaining graphite tiles are installed. The whole assembly underwent final adjustment and calibration after installation in the vacuum vessel

  19. 7 CFR 1400.204 - Limited partnerships, limited liability partnerships, limited liability companies, corporations...

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Limited partnerships, limited liability partnerships, limited liability companies, corporations, and other similar legal entities. 1400.204 Section 1400.204... entities. (a) A limited partnership, limited liability partnership, limited liability company,......

  20. Orind Refractories Limited

    Institute of Scientific and Technical Information of China (English)

    Mr R. Mishra; Group Manging Director

    2005-01-01

    @@ "Sight can be acquired, Vision cannot". Orind Refractories Limited (ORIND), China was formed with this rare vision. At a time when the world was testing the tepid waters of China; Mr. Ravin Jhunjhunwala, Chairman of ORIND and the management of ORIND India had looked over the Great Wall to begin a journey of success. Incorported on 18th August 1994 with an initial investment of USD 5 million, ORL caters to the ever-demanding needs of the steel industry and beyond. Incidentally ORIND was the first wholly owned India company to set up base in China. Pesently, ORIND China has a 616 strong work force including 23 expatriates.

  1. (Limiting the greenhouse effect)

    Energy Technology Data Exchange (ETDEWEB)

    Rayner, S.

    1991-01-07

    Traveler attended the Dahlem Research Conference organized by the Freien Universitat, Berlin. The subject of the conference was Limiting the Greenhouse Effect: Options for Controlling Atmospheric CO{sub 2} Accumulation. Like all Dahlem workshops, this was a meeting of scientific experts, although the disciplines represented were broader than usual, ranging across anthropology, economics, international relations, forestry, engineering, and atmospheric chemistry. Participation by scientists from developing countries was limited. The conference was divided into four multidisciplinary working groups. Traveler acted as moderator for Group 3 which examined the question What knowledge is required to tackle the principal social and institutional barriers to reducing CO{sub 2} emissions'' The working rapporteur was Jesse Ausubel of Rockefeller University. Other working groups examined the economic costs, benefits, and technical feasibility of options to reduce emissions per unit of energy service; the options for reducing energy use per unit of GNP; and the significant of linkage between strategies to reduce CO{sub 2} emissions and other goals. Draft reports of the working groups are appended. Overall, the conference identified a number of important research needs in all four areas. It may prove particularly important in bringing the social and institutional research needs relevant to climate change closer to the forefront of the scientific and policy communities than hitherto.

  2. Smoothness of limit functors

    Indian Academy of Sciences (India)

    Benedictus Margaux

    2015-05-01

    Let be a scheme. Assume that we are given an action of the one dimensional split torus $\\mathbb{G}_{m,S}$ on a smooth affine -scheme $\\mathfrak{X}$. We consider the limit (also called attractor) subfunctor $\\mathfrak{X}_{}$ consisting of points whose orbit under the given action `admits a limit at 0’. We show that $\\mathfrak{X}_{}$ is representable by a smooth closed subscheme of $\\mathfrak{X}$. This result generalizes a theorem of Conrad et al. (Pseudo-reductive groups (2010) Cambridge Univ. Press) where the case when $\\mathfrak{X}$ is an affine smooth group and $\\mathbb{G}_{m,S}$ acts as a group automorphisms of $\\mathfrak{X}$ is considered. It also occurs as a special case of a recent result by Drinfeld on the action of $\\mathbb{G}_{m,S}$ on algebraic spaces (Proposition 1.4.20 of Drinfeld V, On algebraic spaces with an action of $\\mathfrak{G}_{m}$, preprint 2013) in case is of finite type over a field.

  3. Limits to biofuels

    Science.gov (United States)

    Johansson, S.

    2013-06-01

    Biofuel production is dependent upon agriculture and forestry systems, and the expectations of future biofuel potential are high. A study of the global food production and biofuel production from edible crops implies that biofuel produced from edible parts of crops lead to a global deficit of food. This is rather well known, which is why there is a strong urge to develop biofuel systems that make use of residues or products from forest to eliminate competition with food production. However, biofuel from agro-residues still depend upon the crop production system, and there are many parameters to deal with in order to investigate the sustainability of biofuel production. There is a theoretical limit to how much biofuel can be achieved globally from agro-residues and this amounts to approximately one third of todays' use of fossil fuels in the transport sector. In reality this theoretical potential may be eliminated by the energy use in the biomass-conversion technologies and production systems, depending on what type of assessment method is used. By surveying existing studies on biofuel conversion the theoretical limit of biofuels from 2010 years' agricultural production was found to be either non-existent due to energy consumption in the conversion process, or up to 2-6000TWh (biogas from residues and waste and ethanol from woody biomass) in the more optimistic cases.

  4. Limits to biofuels

    Directory of Open Access Journals (Sweden)

    Johansson S.

    2013-06-01

    Full Text Available Biofuel production is dependent upon agriculture and forestry systems, and the expectations of future biofuel potential are high. A study of the global food production and biofuel production from edible crops implies that biofuel produced from edible parts of crops lead to a global deficit of food. This is rather well known, which is why there is a strong urge to develop biofuel systems that make use of residues or products from forest to eliminate competition with food production. However, biofuel from agro-residues still depend upon the crop production system, and there are many parameters to deal with in order to investigate the sustainability of biofuel production. There is a theoretical limit to how much biofuel can be achieved globally from agro-residues and this amounts to approximately one third of todays’ use of fossil fuels in the transport sector. In reality this theoretical potential may be eliminated by the energy use in the biomass-conversion technologies and production systems, depending on what type of assessment method is used. By surveying existing studies on biofuel conversion the theoretical limit of biofuels from 2010 years’ agricultural production was found to be either non-existent due to energy consumption in the conversion process, or up to 2–6000TWh (biogas from residues and waste and ethanol from woody biomass in the more optimistic cases.

  5. Speed Limits for Entanglement

    CERN Document Server

    Hartman, Thomas

    2015-01-01

    We show that in any relativistic system, entanglement entropy obeys a speed limit set by the entanglement in thermal equilibrium. The bound is derived from inequalities on relative entropy with respect to a thermal reference state. Thus the thermal state constrains far-from-equilibrium entanglement dynamics whether or not the system actually equilibrates, in a manner reminiscent of fluctuation theorems in classical statistical mechanics. A similar shape-dependent bound constrains the full nonlinear time evolution, supporting a simple physical picture for entanglement propagation that has previously been motivated by holographic calculations in conformal field theory. We discuss general quantum field theories in any spacetime dimension, but also derive some results of independent interest for thermal relative entropy in 1+1d CFT.

  6. The Limits to Relevance

    Science.gov (United States)

    Averill, M.; Briggle, A.

    2006-12-01

    Science policy and knowledge production lately have taken a pragmatic turn. Funding agencies increasingly are requiring scientists to explain the relevance of their work to society. This stems in part from mounting critiques of the "linear model" of knowledge production in which scientists operating according to their own interests or disciplinary standards are presumed to automatically produce knowledge that is of relevance outside of their narrow communities. Many contend that funded scientific research should be linked more directly to societal goals, which implies a shift in the kind of research that will be funded. While both authors support the concept of useful science, we question the exact meaning of "relevance" and the wisdom of allowing it to control research agendas. We hope to contribute to the conversation by thinking more critically about the meaning and limits of the term "relevance" and the trade-offs implicit in a narrow utilitarian approach. The paper will consider which interests tend to be privileged by an emphasis on relevance and address issues such as whose goals ought to be pursued and why, and who gets to decide. We will consider how relevance, narrowly construed, may actually limit the ultimate utility of scientific research. The paper also will reflect on the worthiness of research goals themselves and their relationship to a broader view of what it means to be human and to live in society. Just as there is more to being human than the pragmatic demands of daily life, there is more at issue with knowledge production than finding the most efficient ways to satisfy consumer preferences or fix near-term policy problems. We will conclude by calling for a balanced approach to funding research that addresses society's most pressing needs but also supports innovative research with less immediately apparent application.

  7. LIMITED LIABILITY DALAM LIMITED LIABILITY PADA KONSTRUKSI PERUSAHAAN KELOMPOK PIRAMIDA

    Directory of Open Access Journals (Sweden)

    Ms. Sulistiowati

    2011-06-01

    Full Text Available Applicability of limited liability in corporate groups with pyramid construction creates a legal loophole in the form of a limited liability within a limited liability. To prevent moral hazard, it is necessary to stipulate new law that limits the number of levels in a corporate group. Berlakunya limited liability pada perusahaan kelompok dengan konstruksi piramida menciptakan celah hukum berupa limited liability dalam limited liability. Untuk mencegah munculnya moral hazard dari pemegang akhir atau induk perbuatan, perlu dilakukan terobosan hukum pembatasan jumlah lapisan anak perusahaan dalam konstruksi perusahaan kelompok.

  8. Capsulorhexis: Its safe limits

    Directory of Open Access Journals (Sweden)

    Vasavada Abhay

    1995-01-01

    Full Text Available We undertook this study to determine the safe limits of capsulorhexis during nucleus expression in 40 eyes of patients undergoing extracapsular cataract extraction (ECCE with a posterior chamber intraocular lens (PC IOL implantation and in 30 cadaver eyes. In group I (patient eyes, capsulorhexis of 4.5 to 7.5 mm was performed and the nucleus was expressed by hydrodissection. The nuclei measured 4.5 to 9.0 mm. One relaxing incision at 12 o′clock position had to be placed in 9 patients. In group II (cadaver eyes, continuous curvilinear capsulotomies of 4.0, 4.5, 5.0, 5.5, 6.0 and 6.5 mm were made in 5 eyes each. No relaxing incisions were placed. In both the groups, nuclei of all sizes could be safely delivered through intact capsulotomies measuring 5.5 mm or more. In two patient eyes, posterior capsule rupture occurred with rhexis measuring 4.5 and 5.0 mm, respectively. In the cadaver eyes, intracapsular extraction occurred in 4 eyes with rhexis measuring 5.0 mm or less. We conclude that a rhexis less than 5.5 mm is not safe for nucleus delivery during ECCE.

  9. GCFR core cladding temperature limits

    International Nuclear Information System (INIS)

    This paper reviews the phenomena that affect selection of the GCFR cladding faulted temperature limit. The limiting effects are determined to be clad melting, strength and oxidation rate. The selected temperature limit is 13000C (23700F). The limits for normal, upset and emergency events are also breifly reviewed, and some changes under consideration are discussed

  10. The limits of deterrence

    International Nuclear Information System (INIS)

    The objective of this contribution is to propose a better insight of the validity of the theory of deterrence, and of related doctrines in more complex and more various situations than in the past: emergence of powers like China and India, of new nuclear States like North Korea and Pakistan, of countries planning to acquire nuclear weapons like Iran, and possibility of a new wave of nuclear proliferation in Middle-East and north-eastern Asia. It also aims at providing arguments in the debates on the struggle against nuclear proliferation and on the future of deterrence. The author first presents and comments the principles of deterrence, and illustrates them by more or less recent historical situations (Iran during the war with Iraq, USA after Pearl Harbour, Arab-Israeli wars, Iraq, and so on). He notably outlines that the notion of deterrence is present in Islamic culture, and that Iran has well integrated it in its defence strategy. Examples of statements and behaviours of other Arab leaders are discussed. The author also briefly indicates how the deterrence strategy is present in the official doctrines of Russia, India, Pakistan, and North Korea. In a second part, based on various examples, the author analyses the practical limitations of deterrence by distinguishing the psychological dimension (bounded rationality, political leaders suffering from various psychological problems, importance of the ideological and spiritual dimension, values prevailing on interests, the case of Iran), and the strategic dimension (good understanding of the enemy, sensitivity of the threat of massive damages, existence of a single decision centre and of an efficient communication). The author finally proposes seven recommendations for better deterrence efficiency

  11. Limits to Tidal Power

    Science.gov (United States)

    Garrett, C.

    2008-12-01

    Ocean tides have been proposed as a source of renewable energy, though the maximum available power may be shown to be only a fraction of the present dissipation rate of 3.5 TW, which is small compared with global insolation (nearly 105 TW), wind dissipation (103 TW), and even human power usage of 15 TW. Nonetheless, tidal power could be a useful contributor in some locations. Traditional use of tidal power, involving the trapping of water behind a barrage at high tide, can produce an average power proportional to the area of the headpond and the square of the tidal range; the power density is approximately 6 W per square meter for a tidal range of 10 m. Capital costs and fears of environmental damage have put barrage schemes in disfavor, with interest turning to the exploitation of strong tidal currents, using turbines in a manner similar to wind turbines. There is a limit to the available power, however, as adding turbines reduces the flow, ultimately reducing the power. For sinusoidal forcing of flow in a channel connecting two large open basins, the maximum available power may be shown to be given approximately by 0.2ρ g a Q_max, where ρ is the water density, g gravity, a the amplitude of the tidal sea level difference along the channel, and Q_max is the maximum volume flux in the natural state. The same formula applies if the channel is the entrance to a semi-enclosed basin, with a now the amplitude of the external tide. A flow reduction of approximately 40% is typically associated with the maximum power extraction. The power would be reduced if only smaller environmental changes are acceptable, and reduced further by drag on supporting structures, dissipation in turbine wakes, and internal inefficiencies. It can be suggested that the best use of strong, cold, tidal currents is to provide cooling water for nuclear reactors.

  12. FED pumped limiter configuration issues

    International Nuclear Information System (INIS)

    Impurity control in the Fusion Engineering Device (FED) is provided by a toroidal belt pumped limiter. Limiter design issues addressed in this paper are (1) poloidal location of the limiter belt, (2) shape of the limiter surface facing the plasma, and (3) whether the belt is pumped from one or both sides. The criteria used for evaluation of limiter configuration features were sensitivity to plasma-edge conditions and ease of maintenance and fabrication. The evaluation resulted in the selection of a baseline FED limiter that is located at the bottom of the device and has a flat surface with a single leading edge

  13. Charter Halibut Limited Access Program

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This limited access system limits the number of charter vessels that may participate in the guided sport fishery for halibut in area 2C and 3A. NMFS issues a...

  14. Scientific Opinion on the safety and efficacy of L-threonine produced by Escherichia coli for all animal species, based on a dossier submitted by HELM AG on behalf of Star Lake Bioscience Co.

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP

    2014-06-01

    Full Text Available The product L-Threonine is a feed additive produced by fermentation with a genetically modified strain of Escherichia coli. L-Threonine is an essential amino acid for all animal species. It is commonly considered the second and third limiting amino acid in cereal-based diets for pigs and poultry, respectively. It is widely used in the feed industry to optimise dietary protein. The amino acid L-threonine itself is considered safe for the target animals, the consumer and the environment. However, the possible presence of the production strain and its recombinant DNA, including antibiotic resistance genes used in the genetic modification process, in the final product cannot be excluded. Consequently, the FEEDAP Panel cannot conclude on the safety of L-threonine produced by fermentation with such E. coli strain for the target animals, consumers and the environment. Regardless of the assessment of the genetic modification, the FEEDAP Panel has concerns regarding the safety of amino acids, including L-threonine, for target species when administered via water for drinking. From the results provided, it is concluded that there is no concern for users in respect of respiratory toxicity, or skin or eye irritancy. In the absence of any data on sensitisation, it is concluded that the product may have the potential to be a dermal sensitiser. The concerns regarding the safety of the genetic modification may also have implications for the safety of the user. The product L-threonine is an efficacious source of supplemented amino acid which helps to maintain or restore the adequate balance of dietary amino acids for all non-ruminant species. Supplemental L-threonine is degraded by ruminal microorganisms if not given in a protected form.

  15. Material Limitations on the Detection Limit in Refractometry

    Directory of Open Access Journals (Sweden)

    Niels Asger Mortensen

    2009-10-01

    Full Text Available We discuss the detection limit for refractometric sensors relying on high-Q optical cavities and show that the ultimate classical detection limit is given by min {Δn} ≳ η with n + iη being the complex refractive index of the material under refractometric investigation. Taking finite Q factors and filling fractions into account, the detection limit declines. As an example we discuss the fundamental limits of silicon-based high-Q resonators, such as photonic crystal resonators, for sensing in a bio-liquid environment, such as a water buffer. In the transparency window (λ ≳ 1100 nm of silicon the detection limit becomes almost independent on the filling fraction, while in the visible, the detection limit depends strongly on the filling fraction because the silicon absorbs strongly.

  16. Material Limitations on the Detection Limit in Refractometry

    CERN Document Server

    Skafte-Pedersen, Peder; Xiao, Sanshui; Mortensen, Niels Asger; 10.3390/s91108382

    2009-01-01

    We discuss the detection limit for refractometric sensors relying on high-Q optical cavities and show that the ultimate classical detection limit is given by min{Dn} > eta with n+i*eta being the complex refractive index of the material under refractometric investigation. Taking finite Q factors and filling fractions into account, the detection limit declines. As an example we discuss the fundamental limits of silicon-based high-Q resonators, such as photonic crystal resonators, for sensing in a bio-liquid environment, such as a water buffer. In the transparency window of silicon the detection limit becomes almost independent on the filling fraction, while in the visible, the detection limit depends strongly on the filling fraction because silicon absorbs strongly.

  17. A ciência como cultura do mundo contemporâneo: a utopia dos saberes das (biociências e a construção midiática do imaginário social Science as culture in the modern world: the utopia of knowledge in (biosciences and the media construction of social imaginary

    Directory of Open Access Journals (Sweden)

    Madel Luz

    2013-04-01

    Full Text Available O artigo trata essencialmente do papel das biociências, visto como uma cultura específica, no imaginário social contemporâneo, no que concerne à vida, à saúde e ao viver humano em todas as suas fases. Os meios de comunicação, sobretudo através da imprensa de divulgação de massa - sendo privilegiada no artigo a imprensa escrita - difundem para o conjunto da sociedade modos de pensar e agir derivadas das atividades científicas, em andamento ou finalizadas, na área das biociências, que compõem um campo disciplinar especializado de amplo espectro. Destacamos no texto a autoridade não apenas intelectual como moral do discurso normativo oriundo dessas atividades, face a outros discursos presentes na cultura, sejam eles tradicionais - de origem nativa ou externa, como as orientais - sejam eles paralelos atuais, como os das chamadas medicinas ou saberes terapêuticos alternativos derivados dos movimentos de contracultura que remontam aos anos setentas. Nossa hipótese é que esta influência normativa atinge áreas do viver e setores cada vez mais amplos das populações, sendo possível afirmar que as ciências sociais, sobretudo a sociologia, não vêm atribuindo à questão da vida e da saúde humanas a mesma importância que atribui a outros aspectos da vida social, e que é urgente pensar a cultura da vida e do viver veiculada pelas biociências.This article deals with the growing influence of the so called biosciences, a large scope of disciplines concerning life, mainly human life, its origin, "normal" characteristics and evolution processes, from birth to death, in present culture. We are particularly interested in the effects of the discoveries and controversies of the diffusion of results of the research process in social imaginary. Through the mass media divulgation -specially press, mainly the magazines having as its objective the scientific research diffusion, an ensemble of rules about the way of conducting "normal" live

  18. Material Limitations on the Detection Limit in Refractometry

    OpenAIRE

    Niels Asger Mortensen; Sanshui Xiao; Peder Skafte-Pedersen; Pedro S. Nunes

    2009-01-01

    We discuss the detection limit for refractometric sensors relying on high-Q optical cavities and show that the ultimate classical detection limit is given by min {Δn} ≳ η with n + iη being the complex refractive index of the material under refractometric investigation. Taking finite Q factors and filling fractions into account, the detection limit declines. As an example we discuss the fundamental limits of silicon-based high-Q resonators, such as photonic crystal resonators, for sensing in a...

  19. Rate limits of sensorimotor synchronization

    Directory of Open Access Journals (Sweden)

    Bruno H. Repp

    2006-01-01

    Full Text Available Empirical evidence for upper and lower rate li-mits of sensorimotor synchronization (typically, finger tapping with anauditory or visual event sequence is reviewed. If biomechanical constraints are avoided, the upper rate limit can be as high as 8-10 Hz (sequence event inter-onset intervals of 100-125 ms with auditory stimuli, but has been found to be less than 2.5 Hz (> 400 ms with simple visual stimuli (flashesof light. The upper rate limit for auditory stimuli varies with task difficulty and musical experience; that for visual stimuli requires further investigation. The lower rate limit, according to one definition,tend stobe at about 0.56 Hz (1800 ms, regardless of modality. Attentional, perceptual, and sensorimotor explanations of these limits are considered. Rate limits of sensorimotor synchronization place important constraints on musical ensemble performance and other forms of rhythmic coordination.

  20. Material limitations on the detection limit in refractometry

    DEFF Research Database (Denmark)

    Skafte-Pedersen, Peder; Nunes, Pedro; Xiao, Sanshui;

    2009-01-01

    We discuss the detection limit for refractometric sensors relying on high-Q optical cavities and show that the ultimate classical detection limit is given by min {Δn} ≳ η with n + iη being the complex refractive index of the material under refractometric investigation. Taking finite Q factors and...

  1. Welfare Dynamics Under Time Limits

    OpenAIRE

    Jeff Grogger; Charles Michalopoulos

    1999-01-01

    Among the most important changes brought about by the Personal Responsibility and Work Opportunity Reconciliation Act of 1996 (PRWORA) is the imposition of time limits. In this paper, we analyze a simple model in which a potential welfare recipient chooses how to allocate her time-limited endowment of benefits so as to maximize her expected lifetime utility. Not surprisingly, the model reveals that time limits provide an incentive for the consumer to conserve, or bank, her benefits. More inte...

  2. Thermodynamic Limit for Polydisperse Fluids

    OpenAIRE

    Banerjee, S.; Griffiths, R. B.; Widom, M.

    2000-01-01

    We examine the thermodynamic limit of fluids of hard core particles that are polydisperse in size and shape. In addition, particles may interact magnetically. Free energy of such systems is a random variable because it depends on the choice of particles. We prove that the thermodynamic limit exists with probability 1, and is independent of the choice of particles. Our proof applies to polydisperse hard-sphere fluids, colloids and ferrofluids. The existence of a thermodynamic limit implies sys...

  3. Limit cycles in quantum systems

    Energy Technology Data Exchange (ETDEWEB)

    Niemann, Patrick

    2015-04-27

    In this thesis we investigate Limit Cycles in Quantum Systems. Limit cycles are a renormalization group (RG) topology. When degrees of freedom are integrated out, the coupling constants flow periodically in a closed curve. The presence of limit cycles is restricted by the necessary condition of discrete scale invariance. A signature of discrete scale invariance and limit cycles is log-periodic behavior. The first part of this thesis is concerned with the study of limit cycles with the similarity renormalization group (SRG). Limit cycles are mainly investigated within conventional renormalization group frameworks, where degrees of freedom, which are larger than a given cutoff, are integrated out. In contrast, in the SRG potentials are unitarily transformed and thereby obtain a band-diagonal structure. The width of the band structure can be regarded as an effective cutoff. We investigate the appearance of limit cycles in the SRG evolution. Our aim is to extract signatures as well as the scaling factor of the limit cycle. We consider the 1/R{sup 2}-potential in a two-body system and a three-body system with large scattering lengths. Both systems display a limit cycle. Besides the frequently used kinetic energy generator we apply the exponential and the inverse generator. In the second part of this thesis, Limit Cycles at Finite Density, we examine the pole structure of the scattering amplitude for distinguishable fermions at zero temperature in the medium. Unequal masses and a filled Fermi sphere for each fermion species are considered. We focus on negative scattering lengths and the unitary limit. The properties of the three-body spectrum in the medium and implications for the phase structure of ultracold Fermi gases are discussed.

  4. Limit cycles in quantum systems

    International Nuclear Information System (INIS)

    In this thesis we investigate Limit Cycles in Quantum Systems. Limit cycles are a renormalization group (RG) topology. When degrees of freedom are integrated out, the coupling constants flow periodically in a closed curve. The presence of limit cycles is restricted by the necessary condition of discrete scale invariance. A signature of discrete scale invariance and limit cycles is log-periodic behavior. The first part of this thesis is concerned with the study of limit cycles with the similarity renormalization group (SRG). Limit cycles are mainly investigated within conventional renormalization group frameworks, where degrees of freedom, which are larger than a given cutoff, are integrated out. In contrast, in the SRG potentials are unitarily transformed and thereby obtain a band-diagonal structure. The width of the band structure can be regarded as an effective cutoff. We investigate the appearance of limit cycles in the SRG evolution. Our aim is to extract signatures as well as the scaling factor of the limit cycle. We consider the 1/R2-potential in a two-body system and a three-body system with large scattering lengths. Both systems display a limit cycle. Besides the frequently used kinetic energy generator we apply the exponential and the inverse generator. In the second part of this thesis, Limit Cycles at Finite Density, we examine the pole structure of the scattering amplitude for distinguishable fermions at zero temperature in the medium. Unequal masses and a filled Fermi sphere for each fermion species are considered. We focus on negative scattering lengths and the unitary limit. The properties of the three-body spectrum in the medium and implications for the phase structure of ultracold Fermi gases are discussed.

  5. Solubility limits on radionuclide dissolution

    Energy Technology Data Exchange (ETDEWEB)

    Kerrisk, J.F.

    1984-12-31

    This paper examines the effects of solubility in limiting dissolution rates of a number of important radionuclides from spent fuel and high-level waste. Two simple dissolution models were used for calculations that would be characteristics of a Yucca Mountain repository. A saturation-limited dissolution model, in which the water flowing through the repository is assumed to be saturated with each waste element, is very conservative in that it overestimates dissolution rates. A diffusion-limited dissolution model, in which element-dissolution rates are limited by diffusion of waste elements into water flowing past the waste, is more realistic, but it is subject to some uncertainty at this time. Dissolution rates of some elements (Pu, Am, Sn, Th, Zr, Sm) are always limited by solubility. Dissolution rates of other elements (Cs, Tc, Np, Sr, C, I) are never solubility limited; their release would be limited by dissolution of the bulk waste form. Still other elements (U, Cm, Ni, Ra) show solubility-limited dissolution under some conditions. 9 references, 3 tables.

  6. Time Limits and Welfare Use

    Science.gov (United States)

    Grogger, Jeffrey

    2004-01-01

    Time limits represent a substantial departure from previous welfare policy. Theory suggests that their effects should vary according to the age of the youngest child of the family. I test this prediction using data from the Current Population Survey and find that time limits indeed have larger effects on families with younger children. I further…

  7. Prediction of Limit Strains in Limiting Dome Height Formability Test

    Science.gov (United States)

    Zadpoor, Amir A.; Sinke, Jos; Benedictus, Rinze

    2007-04-01

    In this paper, the Marciniak-Kunczynski (MK) method is combined with the Storen-Rice analysis in order to improve accuracy of the predicted limit strains in Limiting Dome Height (LDH) test. FEM simulation is carried out by means of a commercial FEM code (ABAQUS) and FEM results are postprocessed by using an improved MK code. It has been shown that while original MK method considerably misspredicts the limit strains, a combination of MK method and Storen-Rice analysis can predict the dome height with a very good accuracy.

  8. Tokamak plasma interaction with limiters

    International Nuclear Information System (INIS)

    The importance of plasma purity is first discussed in terms of the general requirements of controlled thermonuclear fusion. The tokamak approach to fusion and its inherent problem of plasma contamination are introduced. A main source of impurities is due to the bombardment of the limiter by energetic particles and thus the three main aspects of the plasma-limiter interaction are reviewed, boundary plasma conditions, fuelling/recycling and impurity production. The experiments, carried out on the DITE tokamak at Culham Laboratory, UK, investigated these three topics and the results are compared with predicted behaviour; new physical phenomena are presented in all three areas. Simple one-dimensional fluid equations are found to adequately describe the SOL plasma, except in regard to the pre-sheath electric field and ambipolarity; that is, the electric field adjacent to the limiter surface appears to be weak and the associated plasma flow can be non-ambipolar. Recycling of fuel particles from the limiter is observed to be near unity at all times. The break-up behaviour of recycled and gas puffed D2 molecules is dependent on the electron temperature, as expected. Impurity production at the limiter is chemical erosion of graphite being negligible. Deposition of limiter and wall-produced impurities is found on the limiter. The spatial distributions of impurities released from the limiter are observed and are in good agreement with a sputtered atom transport code. Finally, preliminary experiments on the transport of impurity ions along field lines away from the limiter have been performed and compared with simple analytic theory. The results suggest that the pre-sheath electric field in the SOL is much weaker than the simple fluid model would predict

  9. Fundamental Limits of Ultrathin Metasurfaces

    CERN Document Server

    Arbabi, Amir

    2014-01-01

    We present universal theoretical limits on the operation and performance of non-magnetic passive ultrathin metasurfaces. In particular, we prove that their local transmission, reflection, and polarization conversion coefficients are confined to limited regions of the complex plane. As a result, full control over the phase of the light transmitted through such metasurfaces cannot be achieved if the polarization of the light is not to be affected at the same time. We also establish fundamental limits on the maximum polarization conversion efficiency of these metasurfaces, and show that they cannot achieve more than 25% polarization conversion efficiency in transmission.

  10. The plastic limit of clays

    OpenAIRE

    Haigh, Stuart K.; Vardanega, Paul J.; Bolton, Malcolm D.

    2013-01-01

    The plastic limit of soils was first described by Atterberg in 1911. The thread-rolling test was standardised at the US Public Roads Bureau in the 1920s and 1930s, and has subsequently become one of the standard tests of soil mechanics. This paper reviews the original definitions of plastic limit as proposed by Atterberg, and proposes that the brittle failure observed in the plastic limit test is caused by either air entry or cavitation in the clay. Critical state soil mechanics is used to sh...

  11. Limit laws for Zipf's law

    International Nuclear Information System (INIS)

    In this communication we establish stochastic limit laws leading from Zipf's law to Pareto's and Heaps' laws. We consider finite ensembles governed by Zipf's law and study their asymptotic statistics as the ensemble size tends to infinity. A Lorenz-curve analysis establishes three types of limit laws for the ensembles' statistical structure: 'communist', 'monarchic', and Paretian. Further considering a dynamic setting in which the ensembles grow stochastically in time, a functional central limit theorem analysis establishes a Gaussian approximation for the ensembles' stochastic growth. The Gaussian approximation provides a generalized and corrected formulation of Heaps' law. (fast track communication)

  12. Nuclear Structure at the Limits

    International Nuclear Information System (INIS)

    One of the frontiers of today's nuclear science is the ''journey to the limits'': of atomic charge and nuclear mass, of neutron-to-proton ratio, and of angular momentum. The tour to the limits is not only a quest for new, exciting phenomena but the new data are expected, as well, to bring qualitatively new information about the fundamental properties of the nucleonic many-body system, the nature of the nuclear interaction, and nucleonic correlations at various energy-distance scales. In this talk, current developments in nuclear structure at the limits are discussed from a theoretical perspective

  13. Physical limits to biochemical signaling

    CERN Document Server

    Bialek, W

    2003-01-01

    Many crucial biological processes operate with surprisingly small numbers of molecules, and there is renewed interest in analyzing the impact of noise associated with these small numbers. Twenty--five years ago, Berg and Purcell showed that bacterial chemotaxis, where a single celled organism must respond to small changes in concentration of chemicals outside the cell, is limited directly by molecule counting noise, and that aspects of the bacteria's behavioral and computational strategies must be chosen to minimize the effects of this noise. Here we revisit and generalize their arguments to estimate the physical limits to signaling processes within the cell, and argue that recent experiments are consistent with performance approaching these limits.

  14. Nuclear Structure at the Limits

    International Nuclear Information System (INIS)

    One of the frontiers of todays nuclear science is the journey to the limits of atomic charge and nuclear mass, of neutron-to-proton ratio, and of angular momentum. The tour to the limits is not only a quest for new, exciting phenomena, but the new data are expected, as well, to bring qualitatively new information about the fundamental properties of the nucleonic many-body system, the nature of the nuclear interaction, and nucleonic correlations at various energy-distance scales. In this series of lectures, current developments in nuclear structure at the limits are discussed from a theoretical perspective, mainly concentrating on medium-mass and heavy nuclei

  15. A cidade: limite do mundo

    OpenAIRE

    Borges Abel, António

    2010-01-01

    A cidade é hoje, por força do desenvolvimento das NTIC, uma cidade alargada ou, se se preferir, uma “aldeia global”. Porém, se sob o ponto de vista da comunicação, os limites da cidade se confundem com os limites do mundo, sob o ponto de vista da cidade física, geográfica, o “capitalismo cognitivo” força cada vez mais aquela a não conhecer limites, a transformar a hibridez num novo conceito e numa nova realidade espacial, pulverizando a anterior realidade: a cidade como contraponto do camp...

  16. Nuclear Structure at the Limits

    Energy Technology Data Exchange (ETDEWEB)

    Nazarewicz, Witold

    1997-12-31

    One of the frontiers of today`s nuclear science is the ``journey to the limits``: of atomic charge and nuclear mass, of neutron-to-proton ratio, and of angular momentum. The tour to the limits is not only a quest for new, exciting phenomena but the new data are expected, as well, to bring qualitatively new information about the fundamental properties of the nucleonic many-body system, the nature of the nuclear interaction, and nucleonic correlations at various energy-distance scales. In this talk, current developments in nuclear structure at the limits are discussed from a theoretical perspective.

  17. Quasi-Static Hydrodynamic Limits

    Science.gov (United States)

    De Masi, Anna; Olla, Stefano

    2015-12-01

    We consider hydrodynamic limits of interacting particles systems with open boundaries, where the exterior parameters change in a time scale slower than the typical relaxation time scale. The limit deterministic profiles evolve quasi-statically. These limits define rigorously the thermodynamic quasi static transformations also for transitions between non-equilibrium stationary states. We study first the case of the symmetric simple exclusion, where duality can be used, and then we use relative entropy methods to extend to other models like zero range systems. Finally we consider a chain of anharmonic oscillators in contact with a thermal Langevin bath with a temperature gradient and a slowly varying tension applied to one end.

  18. Brassicas limited in weed control

    OpenAIRE

    Kristiansen, Mr P

    2006-01-01

    This article discusses the limitations of using brassica cover crops for weed control. A brief overview of the role of cover crops is provided, followed by a short review of research looking at brassica cover crops.

  19. Multifamily Tax Subsidy Income Limits

    Data.gov (United States)

    Department of Housing and Urban Development — Multifamily Tax Subsidy Projects (MTSP) Income Limits were developed to meet the requirements established by the Housing and Economic Recovery Act of 2008 (Public...

  20. Limited-Access Heart Surgery

    Science.gov (United States)

    ... Heart tumor removal Atrial septal defect (ASD) repair Patent foramen ovale repair Catheter ablation for atrial fibrillation As with other kinds of limited-access surgery, robotic-assisted surgery can mean shorter hospital stays and ...

  1. Casimir Effect The Classical Limit

    CERN Document Server

    Feinberg, J; Revzen, M

    2001-01-01

    We analyze the high temperature limit of the Casimir effect. A simple physical argument suggests that the Casimir energy (as opposed to the Casimir free energy) should vanish in the classical limit. We check the validity of this argument for massless scalar field confined in a cavity with boundaries of arbitrary shape, using path integral formalism. We are able to verify this suggestion only when the boundaries consist of disjoint pieces. Moreover, we find in these cases that the contribution to the Casimir entropy by field modes that depend on that separation, tends, in the classical limit, to a finite asymptotic value which depends only on the geometry of the cavity. Thus the Casimir force between disjoint pieces of the boundary in the classical limit is entropy driven and is governed by a dimensionless number characterizing the arbitrary geometry of the cavity. Contributions to the Casimir thermodynamical quantities due to each individual connected component of the boundary exhibit logarithmic deviations i...

  2. Superconducting dc fault current limiter

    International Nuclear Information System (INIS)

    Within the framework of the electric power market liberalization, DC networks have many interests compared to alternative ones, but their protections need to use new systems. Superconducting fault current limiters enable by an overstepping of the critical current to limit the fault current to a preset value, lower than the theoretical short-circuit current. For these applications, coated conductors offer excellent opportunities. We worked on the implementation of these materials and built a test bench. We carried out limiting experiments to estimate the quench homogeneity at various short-circuit parameters. An important point is the temperature measurement by deposited sensors on the ribbon, results are in good correlation with the theoretical models. Improved quench behaviours for temperatures close to the critical temperature have been confirmed. Our results enable to better understand the limitation mechanisms of coated conductors. (author)

  3. Limits on the photon mass

    International Nuclear Information System (INIS)

    Is the photon mass strictly null as it is told in quantum electrodynamics. In fact, a coherent theory can be build with a massive photon. Experiences have been regularly led to try to make obvious an eventual non null photon mass. Superior limits more and more strict have been found. Here is given a general survey of the consequences of a non null photon mass, different methods to measure it and the achieved limits. (author). 30 refs., 1 fig

  4. Limit cycles of effective theories

    OpenAIRE

    Glazek, Stanislaw D.

    2006-01-01

    A simple example is used to show that renormalization group limit cycles of effective quantum theories can be studied in a new way. The method is based on the similarity renormalization group procedure for Hamiltonians. The example contains a logarithmic ultraviolet divergence that is generated by both real and imaginary parts of the Hamiltonian matrix elements. Discussion of the example includes a connection between asymptotic freedom with one scale of bound states and the limit cycle with a...

  5. Penrose limits and maximal supersymmetry

    International Nuclear Information System (INIS)

    We show that the maximally supersymmetric pp-wave of IIB superstring and M-theories can be obtained as a Penrose limit of the supersymmetric AdSxS solutions. In addition, we find that in a certain large tension limit, the geometry seen by a brane probe in an AdSxS background is either Minkowski space or a maximally supersymmetric pp-wave. (letter to the editor)

  6. Time Limits and Welfare Use

    OpenAIRE

    Jeff Grogger

    2000-01-01

    Time limits are a central component of recent welfare reforms and represent a substantial departure from previous policy. However, several recent studies suggest that they have had no effect on welfare use. In this paper I attempt to reconcile those findings with results from Grogger and Michalopoulos, who find time limits to have substantial effects that vary by the age of the youngest child in the family. Using data from the Current Population Survey, I obtain results similar to those of pr...

  7. Penrose Limits and Spacetime Singularities

    OpenAIRE

    Blau, Matthias; Borunda, Monica; O'Loughlin, Martin; Papadopoulos, George

    2003-01-01

    We give a covariant characterisation of the Penrose plane wave limit: the plane wave profile matrix $A(u)$ is the restriction of the null geodesic deviation matrix (curvature tensor) of the original spacetime metric to the null geodesic, evaluated in a comoving frame. We also consider the Penrose limits of spacetime singularities and show that for a large class of black hole, cosmological and null singularities (of Szekeres-Iyer ``power-law type''), including those of the FRW and Schwarzschil...

  8. Time Limits : Effects on Recall

    OpenAIRE

    Hirano, Kinue

    2000-01-01

    This study investigates the effects of differing time limits and the level of language proficiency on the written recalls of 66 Japanese EFL undergraduates. Results showed that different time limits affected total recall, but not main ideas recalled. Regardless of proficiency level, the 20-minute group (Group 2) recalled a greater number of idea units than the 8-minute group (Group 1). However, no significant difference was found between Groups 1 and 2 regarding the recall of main ideas, alth...

  9. Cloning: Past, Present, and the Exciting Future. Breakthroughs in Bioscience.

    Science.gov (United States)

    Di Berardino, Marie A.

    This document explores the history of cloning by focusing on Dolly the Sheep, one of the first large animal clonings. The disadvantages and advantages of transgenic clones are discussed as well as the future implications of cloning from the perspective of human health. (Contains 10 resources.) (YDS)

  10. The bioscience revolution & the biological weapons threat: levers & interventions

    Directory of Open Access Journals (Sweden)

    Martin Greg

    2009-02-01

    Full Text Available Abstract In December 2008, the US Commission on the Prevention of Weapons of Mass Destruction Proliferation and Terrorism, released a report, World At Risk. The Report points to the fact that, not only is the use of a weapon of mass destruction in a terrorist attack before the end of 2013, more likely than not, but also to the fact that terrorists are more likely to be able to obtain and use biological weapons than nuclear. This paper examines the recommendations of the report in the context of the historic and geopolitical changes, in particular globalization. The authors highlight the "dual-use" dilemma, as described in the report, as the paradoxical use of technology developed for the benefit of mankind being used for sinister purposes. The mitigation of such a threat lies in broad stakeholder involvement and cooperation, including non-state actors, governments and the bio-tech industry itself. The importance of vigilance measures within the life science community is emphasized and, the authors propose, could include a web-based didactic course in bioterrorism and weapons of mass destruction identification. The site could outline safety protocols, have detailed disaster management tutorials, and could be specifically tailored for different subsets of industry and health professionals. The paper concludes with an endorsement of a multi-pronged approach including strong international guidelines and intelligence cooperation and preparatory measures such as the wide-spread use of detection systems as well as diagnostic decision support systems for bioterrorism detection at the local level.

  11. The bioscience revolution & the biological weapons threat: levers & interventions

    OpenAIRE

    Martin Greg; D'Agostino Mark

    2009-01-01

    Abstract In December 2008, the US Commission on the Prevention of Weapons of Mass Destruction Proliferation and Terrorism, released a report, World At Risk. The Report points to the fact that, not only is the use of a weapon of mass destruction in a terrorist attack before the end of 2013, more likely than not, but also to the fact that terrorists are more likely to be able to obtain and use biological weapons than nuclear. This paper examines the recommendations of the report in the context ...

  12. Statistical limitations on molecular evolution.

    Science.gov (United States)

    Perlovsky, Leonid I

    2002-06-01

    Complexity of functions evolving in an evolution process are expected to be limited by the time length of an evolution process among other factors. This paper outlines a general method of deriving function-complexity limitations based on mathematical statistics and independent from details of a biological or genetic mechanism of the evolution of the function. Limitations on the emergence of life are derived, these limitations indicate a possibility of a very fast evolution and are consistent with "RNA world" hypothesis. The discussed method is general and can be used to characterize evolution of more specific biological organism functions and relate functions to genetic structures. The derived general limitations indicate that a co-evolution of multiple functions and species could be a slow process, whereas an evolution of a specific function might proceed very fast, so that no trace of intermediate forms (species) is preserved in fossil records of phenotype or DNA structure; this is consistent with a picture of "punctuated equilibrium". PMID:12023805

  13. Fermi coordinates and Penrose limits

    Energy Technology Data Exchange (ETDEWEB)

    Blau, Matthias; Frank, Denis; Weiss, Sebastian [Institut de Physique, Universite de Neuchatel Rue Breguet 1, CH-2000 Neuchatel (Switzerland)

    2006-06-07

    We propose a formulation of the Penrose plane wave limit in terms of null Fermi coordinates. This provides a physically intuitive (Fermi coordinates are direct measures of geodesic distance in spacetime) and manifestly covariant description of the expansion around the plane wave metric in terms of components of the curvature tensor of the original metric, and generalizes the covariant description of the lowest order Penrose limit metric itself, obtained in Blau et al (2004 Class. Quantum Grav. 21 L43-9). We describe in some detail the construction of null Fermi coordinates and the corresponding expansion of the metric, and then study various aspects of the higher order corrections to the Penrose limit. In particular, we observe that in general the first-order corrected metric is such that it admits a light-cone gauge description in string theory. We also establish a formal analogue of the Weyl tensor peeling theorem for the Penrose limit expansion in any dimension, and we give a simple derivation of the leading (quadratic) corrections to the Penrose limit of AdS{sub 5} x S{sup 5}.

  14. Generalized Geometric Quantum Speed Limits

    Science.gov (United States)

    Pires, Diego Paiva; Cianciaruso, Marco; Céleri, Lucas C.; Adesso, Gerardo; Soares-Pinto, Diogo O.

    2016-04-01

    The attempt to gain a theoretical understanding of the concept of time in quantum mechanics has triggered significant progress towards the search for faster and more efficient quantum technologies. One of such advances consists in the interpretation of the time-energy uncertainty relations as lower bounds for the minimal evolution time between two distinguishable states of a quantum system, also known as quantum speed limits. We investigate how the nonuniqueness of a bona fide measure of distinguishability defined on the quantum-state space affects the quantum speed limits and can be exploited in order to derive improved bounds. Specifically, we establish an infinite family of quantum speed limits valid for unitary and nonunitary evolutions, based on an elegant information geometric formalism. Our work unifies and generalizes existing results on quantum speed limits and provides instances of novel bounds that are tighter than any established one based on the conventional quantum Fisher information. We illustrate our findings with relevant examples, demonstrating the importance of choosing different information metrics for open system dynamics, as well as clarifying the roles of classical populations versus quantum coherences, in the determination and saturation of the speed limits. Our results can find applications in the optimization and control of quantum technologies such as quantum computation and metrology, and might provide new insights in fundamental investigations of quantum thermodynamics.

  15. Impossibility - The Limits of Science and the Science of Limits

    Science.gov (United States)

    Barrow, John D.

    1999-10-01

    In Impossibility , John D. Barrow--one of our most elegant and accomplished science writers--argues convincingly that there are limits to human discovery, that there are things that are ultimately unknowable, undoable, or unreachable. Barrow first examines the limits of the human mind: our brain evolved to meet the demands of our immediate environment, and much that lies outside this small circle may also lie outside our understanding. He investigates practical impossibilities, such as those imposed by complexity, uncomputability, or the finiteness of time, space, and resources. Is the universe finite or infinite? Can information be transmitted faster than the speed of light? The book also examines deeper theoretical restrictions on our ability to know, including Godel's theorem, which proved that there were things that could not be proved. Finally, having explored the limits imposed on us from without, Barrow considers whether there are limits we should impose upon ourselves. Weaving together this intriguing tapestry, Barrow illuminates some of the most profound questions of science, from the possibility of time travel to the very structure of the universe.

  16. Limits of downstream hydraulic geometry

    Science.gov (United States)

    Wohl, Ellen

    2004-10-01

    Adjustments to flow width, depth, and velocity in response to changes in discharge are commonly characterized by using downstream hydraulic geometry relationships. The spatial limits of these relationships within a drainage basin have not been systematically quantified. Where the erosional resistance of the channel substrate is sufficiently large, hydraulic driving forces presumably will be unable to adjust channel form. Data sets from 10 mountain rivers in the United States, Panama, Nepal, and New Zealand are used in this study to explore the limits of downstream hydraulic geometry relationships. Where the ratio of stream power to sediment size (Ω/D84) exceeds 10,000 kg/s3, downstream hydraulic geometry is well developed; where the ratio falls below 10,000 kg/s3, downstream hydraulic geometry relationships are poorly developed. These limitations on downstream hydraulic geometry have important implications for channel engineering and simulations of landscape change.

  17. Shrinkage limit of soil mixtures

    International Nuclear Information System (INIS)

    Shrinkage limit, one of the Atterberg limits, is widely linked with many plasticity-based soil behaviors. However, in a great majority of these cases, such correlations have been found to exhibit poor performance. Recently, it has been brought out that the shrinkage limit of a natural soil does not depend upon plasticity characteristics, and it is primarily governed by the relative grain size distribution of the soil. The present study confirms this mechanism with the results obtained using clay-clay, clay-non-cohesive soil, and non-cohesive soil mix systems. The present study gains importance from the point of view of criteria with respect to the design of back fill materials to be used in various applications, such as nuclear waste disposal projects

  18. Limitations on quantum key repeaters.

    Science.gov (United States)

    Bäuml, Stefan; Christandl, Matthias; Horodecki, Karol; Winter, Andreas

    2015-01-01

    A major application of quantum communication is the distribution of entangled particles for use in quantum key distribution. Owing to noise in the communication line, quantum key distribution is, in practice, limited to a distance of a few hundred kilometres, and can only be extended to longer distances by use of a quantum repeater, a device that performs entanglement distillation and quantum teleportation. The existence of noisy entangled states that are undistillable but nevertheless useful for quantum key distribution raises the question of the feasibility of a quantum key repeater, which would work beyond the limits of entanglement distillation, hence possibly tolerating higher noise levels than existing protocols. Here we exhibit fundamental limits on such a device in the form of bounds on the rate at which it may extract secure key. As a consequence, we give examples of states suitable for quantum key distribution but unsuitable for the most general quantum key repeater protocol. PMID:25903096

  19. An exact limit of ABJM

    CERN Document Server

    Bianchi, Marco S

    2016-01-01

    We study planar ABJM in a limit where one coupling is negligible compared to the other. We provide a recipe for exactly solving the expectation value of bosonic BPS Wilson loops on arbitrary smooth contours, or the leading divergence for cusped ones, using results from localization. As an application, we compute the exact (generalized) cusp anomalous dimension and Bremsstrahlung function and use it to determine the interpolating $h$-function. We finally prove a conjecture on the exact form of the dilatation operator in a closed sector, hinting at the integrability of this limit.

  20. Energy-limited escape revised

    OpenAIRE

    Salz, M.; Schneider, P. C.; Czesla, S.; Schmitt, J. H. M. M.

    2015-01-01

    Gas planets in close proximity to their host stars experience photoevaporative mass loss. The energy-limited escape concept is generally used to derive estimates for the planetary mass-loss rates. Our photoionization hydrodynamics simulations of the thermospheres of hot gas planets show that the energy-limited escape concept is valid only for planets with a gravitational potential lower than $\\log_\\mathrm{10}\\left( -\\Phi_{\\mathrm{G}}\\right) < 13.11~$erg$\\,$g$^{-1}$ because in these planets th...

  1. Penser aux/les limites de nos limites

    Directory of Open Access Journals (Sweden)

    Jacques Lévy

    2010-12-01

    Full Text Available Le mot « frontière » a beaucoup de succès, dans son sens propre mais plus encore comme métaphore d’une multitude de réalités qui ont à voir avec les limites, c’est-à-dire avec notre propension à découper le monde en objets séparables. Mais on constate une grande indétermination entre concept et métaphore et un usage trop facile de mélanges entre ceux-ci. Il faut donc d’abord admettre que la matérialité n’est qu’une des composantes de notre monde, mais que l’immatériel n’est pas l’irréel, le simulé ou le métaphorique. Après un détour par une théorie des limites et ses limites et une distinction entre le topographique (continu et le topologique (discontinu appliquée à l’intérieur et aux limites d’une aire, deux exemples sont développés qui visent à montrer que, si l’on trouve des frontières, ce n’est pas forcément là où on les attend et que l’appréciation juste de la place des frontières suppose la prise en compte de bien d’autres considérations que la seule limitation volontaire et brutale du franchissement d’une ligne imaginaire tracée au sol.Think about limits and the limits of our limitsThe word “boundary” has been very successful in its literal sense but even more so as a metaphor of a multitude of realities involving limits, that is, with regards to our tendency to divide the world into separable objects. However, one can observe a considerable uncertainty between the concept and the metaphor and an utilisation too easy of various mixtures of them. It becomes necessary therefore to first admit that materiality is only one of the components of our world whilst the immaterial is not unreal, simulated or metaphoric. After a detour consisting of examining a theory of limits and its limits and making the distinction between the topographic (continuous and the topologic (discontinuous applied to the interior and the limits of an area, two examples are developed which aim to

  2. ITER operating limit definition criteria

    Energy Technology Data Exchange (ETDEWEB)

    Ciattaglia, S. [EFDA-CSU Boltzmannstrasse 2, D-85748 Garching (Germany)], E-mail: sergio.ciattaglia@tech.efda.org; Barabaschi, P. [EFDA-CSU Boltzmannstrasse 2, D-85748 Garching (Germany); Carretero, J.A. [Empresarios Agrupados, Magallanes, 3 28015 Madrid (Spain); Chiocchio, S. [JWS Garching, Boltzmannstrasse 2, D-85748 Garching (Germany); Hureau, D. [AREVA NP, Tour AREVA, 92084 - Paris, La Defense Cedex (France); Girard, J.Ph.; Gordon, C. [ITER-JWS, Cadarache, St Paul Lez Durance F-13108 (France); Portone, A. [EFDA-CSU Boltzmannstrasse 2, D-85748 Garching bei Muenchen (Germany); Rodrigo, L. Rodriguez [EFDA CSU C/JosepPla, n 2, Torres Diagonal Litoral, Bldg B3. E-08019-Barcelona (Spain); Roldan, C. [CIEMAT, Avd. Complutense, 22-E-28040 Madrid (Spain); Saibene, G. [EFDA-CSU Boltzmannstrasse 2, D-85748 Garching (Germany); Uzan-Elbez, J. [Agence ITER-France, Cadarache, St Paul Lez Durance F-13108 (France)

    2009-12-15

    The operating limits and conditions (OLCs) are operating parameters and conditions, chosen among all system/components, which, together, define the domain of the safe operation of ITER in all foreseen ITER states (operation, maintenance, commissioning). At the same time they are selected to guarantee the required operation flexibility which is a critical factor for the success of an experimental machine such as ITER. System and components that are important for personnel or public safety (safety important class, SIC) are identified considering their functional importance in the overall plant safety analysis. SIC classification has to be presented already in the preliminary safety analysis report and approved by the licensing authority before manufacturing and construction. OLCs comprise the safety limits that, if exceeded, could result in a potential safety hazard, the relevant settings that determine the intervention of SIC systems, and the operational limits on equipment which warn against or stop a functional deviation from a planned operational status that could challenge equipment and functions. Some operational conditions, e.g. in-Vacuum Vessel (VV) radioactive inventories, will be controlled through procedures. Operating experience from present tokamaks, in particular JET, and from nuclear plants, is considered to the maximum possible extent. This paper presents the guidelines for the development of the ITER OLCs with particular reference to safety limits.

  3. Fano-noise-limited CCDs

    Science.gov (United States)

    Janesick, James; Elliott, Tom; Bredthauer, Richard; Chandler, Charles; Burke, Barry

    1988-01-01

    Recent developments of scientific CCDs have produced sensors that achieve ultra low read noise performance (less than 2 electrons rms) and near perfect charge transfer efficiency (0.9999996) without the addition of a fat-zero. This progress has now made it possible to achieve Fano-noise-limited performance in the soft X-ray where the detector's energy resolution is primarily limited by the statistical variation in the charge generated by the interacting X-ray photon. In this paper, Fano-noise-limited test data is presented for two different CCD types and a CCD derived estimate of the Fano factor is determined. By evaluating ultra low-modulation images (less than 1 electron peak-to-peak) it is shown that the CCD's global CTE is now superior to its read noise floor. To capitalize on this capability CCD manufacturers are now focusing their attention on reducing the noise floor below the 1 electron level thereby matching the sensor's CTE performance. This improvement, if accomplished, will push Fano-noise-limited performance for the CCD into the extreme ultra-violet.

  4. Global limits of gauged supergravity

    NARCIS (Netherlands)

    Hohm, Olaf

    2009-01-01

    World-volume actions for multiple M2 and D2 branes are constructed by taking the limit of 2 + 1 dimensional gauged supergravities to globally supersymmetric N = 8 theories on flat space. The embedding tensor formalism adopted for the classification of gauged supergravities is thereby shown to provid

  5. Limitations of Agile Software Processes

    OpenAIRE

    Turk, Dan; France, Robert; Rumpe, Bernhard

    2014-01-01

    Software developers and project managers are struggling to assess the appropriateness of agile processes to their development environments. This paper identifies limitations that apply to many of the published agile processes in terms of the types of projects in which their application may be problematic.

  6. Certifying Equality With Limited Interaction

    DEFF Research Database (Denmark)

    Brody, Joshua Eric; Chakrabarti, Amit; McGregor, Andrew; Kondapally, Ranganath

    focusing on two subtle aspects. The first is to consider the {\\em expected} communication cost (at a worst-case input) for a protocol that uses limited interaction---i.e., a bounded number of rounds of communication---and whose error probability is zero or close to it. The second is to consider the {\\em...

  7. Globalization and limit to growth

    International Nuclear Information System (INIS)

    A global financial crisis is not the only concern the world should have. From oil and other commodities new challenges arise, that could be difficult to face properly and could provide another limit to growth. This Malthusian feature of the 21. century emerges clearly if one focuses on climate change.

  8. Limits of time in cosmology

    CERN Document Server

    Rugh, Svend E

    2016-01-01

    We provide a discussion of some main ideas in our project about the physical foundation of the time concept in cosmology. It is standard to point to the Planck scale (located at $\\sim 10^{-43}$ seconds after a fictitious "Big Bang" point) as a limit for how far back we may extrapolate the standard cosmological model. In our work we have suggested that there are several other (physically motivated) interesting limits -- located at least thirty orders of magnitude before the Planck time -- where the physical basis of the cosmological model and its time concept is progressively weakened. Some of these limits are connected to phase transitions in the early universe which gradually undermine the notion of 'standard clocks' widely employed in cosmology. Such considerations lead to a 'scale problem' for time which becomes particularly acute above the electroweak phase transition (before $\\sim 10^{-11}$ seconds). Other limits are due to problems of building up a cosmological reference frame, or even contemplating a s...

  9. Economic Downturn Limits Conference Travel

    Science.gov (United States)

    Young, Jeffrey R.

    2009-01-01

    Attendance is down at many academic and professional conferences in higher education this year, and next year's numbers are expected to be far worse, as campus budgets take further beatings. With many colleges limiting travel to professors or administrators who are speaking at events they are attending, will anyone be left in the audience? A new…

  10. Environmental risk limits for zinc

    NARCIS (Netherlands)

    Bodar CWM; SEC

    2007-01-01

    Environmental Riks Limits (ERLs) were derived for zinc. ERLs serve as advisory values to set environmental quality standards in the Netherlands. The ERLs for zinc closely follow the outcomes of earlier discussions on zinc within the Water Framework Directive and EC Regulation 793/93. The ERLs refer

  11. Environmental risk limits for zinc

    NARCIS (Netherlands)

    Bodar CWM; SEC

    2007-01-01

    Environmental Riks Limits (ERLs) were derived for zinc. ERLs serve as advisory values to set environmental quality standards in the Netherlands. The ERLs for zinc closely follow the outcomes of earlier discussions on zinc within the Water Framework Directive and EC Regulation 793/93. The ERLs ref

  12. Explosion limits for combustible gases

    Institute of Scientific and Technical Information of China (English)

    TONG Min-ming; WU Guo-qing; HAO Ji-fei; DAI Xin-lian

    2009-01-01

    Combustible gases in coal mines are composed of methane, hydrogen, some multi-carbon alkane gases and other gases. Based on a numerical calculation, the explosion limits of combustible gases were studied, showing that these limits are related to the concentrations of different components in the mixture. With an increase of C4H10 and C6H14, the Lower ExplosionLimit (LEL) and Upper Explosion-Limit (UEL) of a combustible gas mixture will decrease clearly. For every 0.1% increase in C4H10 and C6H14, the LEL decreases by about 0.19% and the UEL by about 0.3%. The results also prove that, by increasing the amount of H2, the UEL of a combustible gas mixture will increase considerably. If the level of H2 increases by 0.1%, the UEL will increase by about 0.3%. However, H2 has only a small effect on the LEL of the combustible gas mixture. Our study provides a theoretical foundation for judging the explosion risk of an explosive gas mixture in mines.

  13. ITER operating limit definition criteria

    International Nuclear Information System (INIS)

    The operating limits and conditions (OLCs) are operating parameters and conditions, chosen among all system/components, which, together, define the domain of the safe operation of ITER in all foreseen ITER states (operation, maintenance, commissioning). At the same time they are selected to guarantee the required operation flexibility which is a critical factor for the success of an experimental machine such as ITER. System and components that are important for personnel or public safety (safety important class, SIC) are identified considering their functional importance in the overall plant safety analysis. SIC classification has to be presented already in the preliminary safety analysis report and approved by the licensing authority before manufacturing and construction. OLCs comprise the safety limits that, if exceeded, could result in a potential safety hazard, the relevant settings that determine the intervention of SIC systems, and the operational limits on equipment which warn against or stop a functional deviation from a planned operational status that could challenge equipment and functions. Some operational conditions, e.g. in-Vacuum Vessel (VV) radioactive inventories, will be controlled through procedures. Operating experience from present tokamaks, in particular JET, and from nuclear plants, is considered to the maximum possible extent. This paper presents the guidelines for the development of the ITER OLCs with particular reference to safety limits.

  14. Illustrating the Central Limit Theorem

    Science.gov (United States)

    Corcoran, Mimi

    2016-01-01

    Statistics is enjoying some well-deserved limelight across mathematics curricula of late. Some statistical concepts, however, are not especially intuitive, and students struggle to comprehend and apply them. As an AP Statistics teacher, the author appreciates the central limit theorem as a foundational concept that plays a crucial role in…

  15. Income trusts and limited partnerships

    International Nuclear Information System (INIS)

    This author provided a conceptual overview of income trusts and limited partnerships that are designed to pass operating cash flow directly to investors without the imposition of corporate taxes, discussed the evolution of the market, the mechanism used to price income funds, past and present performance of the sector, and made some predictions concerning the sector's future performance. 13 figs

  16. Primary pump suction pressure limits

    International Nuclear Information System (INIS)

    In conjunction with the operational testing program which was carried out prior to the startup of N Reactor, a study was carried out to establish limits for suction pressure of the primary (reactor coolant) pumps. The purpose of the report is to document the results of the study and interpret them with respect to the current mode of reactor operation

  17. Thermal-hydraulic limitations on water-cooled limiters

    International Nuclear Information System (INIS)

    An assessment of the cooling requirements for fusion reactor components, such as the first wall and limiter/divertor, was carried out using pressurized water as the coolant. In order to establish the coolant operating conditions, a survey of the literature on departure from nucleate boiling, critical heat flux, asymmetrical heating and heat transfer augmentation techniques was carried out. The experimental data and the empirical correlations indicate that thermal protection for the fusion reactor components based on current design concepts can be provided with an adequate margin of safety without resorting to either high coolant velocities, excessive coolant pressures, or heat transfer augmentation techniques. If, however, the future designs require heat transfer enhancement techniques, experimental verification would be necessary since no data on heat transfer augmentation techniques exist for complex geometries, especially under asymmetrically heated conditions. Since the data presented herein concern primarily thermal protection, the final design should consider other factors such as thermal stresses, temperature limits, and fatigue

  18. 40 CFR 161.175 - Certified limits.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Certified limits. 161.175 Section 161... Certified limits. The applicant must propose certified limits for the ingredients in the product. Certified limits become legally binding limits upon approval of the application. Certified limits will apply to...

  19. Penrose limits and spacetime singularities

    Energy Technology Data Exchange (ETDEWEB)

    Blau, M [Institut de Physique, Universite de Neuchatel, Rue Breguet 1, CH-2000 Neuchatel (Switzerland); Borunda, M [SISSA Scuola Internazionale Superiore di Studi Avanzati, Via Beirut 4, I-34014 Trieste (Italy); O' Loughlin, M [SISSA Scuola Internazionale Superiore di Studi Avanzati, Via Beirut 4, I-34014 Trieste (Italy); Papadopoulos, G [Department of Mathematics, King' s College London, London WC2R 2LS (United Kingdom)

    2004-04-07

    We give a covariant characterization of the Penrose plane wave limit: the plane wave profile matrix A(u) is the restriction of the null geodesic deviation matrix (curvature tensor) of the original spacetime metric to the null geodesic, evaluated in a comoving frame. We also consider the Penrose limits of spacetime singularities and show that for a large class of black hole, cosmological and null singularities (of Szekeres-Iyer 'power-law type'), including those of the FRW and Schwarzschild metrics, the result is a singular homogeneous plane wave with profile A(u) {approx} u{sup -2}, the scale invariance of the latter reflecting the power-law behaviour of the singularities. (letter to the editor)

  20. Swimming as a limit cycle

    CERN Document Server

    Jacobs, Henry O

    2012-01-01

    Steady swimming can be characterized as both periodic and stable. These characteristics are the very definition of limit cycles, and so we ask "Can we view swimming as a limit cycle?" In this paper we will find that the answer is "yes". We will define a class of dissipative systems which correspond to the passive dynamics of a body immersed in a Navier-Stokes fluid (i.e. the dynamics of a dead fish). Upon performing reduction by symmetry we will find a hyperbolically stable fixed point which corresponds to the stability of a dead fish in stagnant water. Given a periodic force on the shape of the body we will invoke the persistence theorem to assert the existence of a loop which approximately satisfies the exact equations of motion. If we lift this loop with a phase reconstruction formula we will find that the lifted loops are not loops, but stable trajectories which represent regular periodic motion reminiscent of swimming.

  1. Mesures à la limite quantique

    OpenAIRE

    Heidmann, Antoine

    2007-01-01

    Doctoral Bien que les principes de base de la mesure en mécanique quantique soient connus depuis longtemps, ce n'est que récemment que les expériences ont été confrontées à ses conséquences. Les effets d'action en retour de la mesure et les limites quantiques associées sont aujourd'hui des notions essentielles dans un certain nombre d'expériences ultrasensibles, et la possibilité d'aller au-delà de ces limites par différentes techniques de compression du bruit ou de mesure non destructive ...

  2. Limitation and life in space

    Science.gov (United States)

    Israel, Marvin; Smith, T. Scott

    1986-08-01

    ``The Earth is the very quintescence of the human condition...,'' says Hannah Arendt. Georg Simmel writes: ``The stranger is by nature no `owner of soil'—soil not only in the physical, but also in the figurative sense of a life-substance which is fixed, if not in a point in space, at least in an ideal point of social environment.'' How will no longer being Earthbound affect persons' experience of themselves and of others? Space colonization offers an opportunity for new self-definition by the alteration of existing limits. Thus ``limitation'' is a useful concept for exploring the physical, social and psychological significance of the colonization of space. Will people seek the security of routine, of convention, of hierarchy as in the military model governing our present-day astronauts? or will they seek to maximize the freedom inherent in extraordinary living conditions—as bohemians, deviants, travelers?

  3. Nuclear Structure at the Limits

    Energy Technology Data Exchange (ETDEWEB)

    Nazarewicz, W.

    1998-01-12

    One of the frontiers of today�s nuclear science is the �journey to the limits� of atomic charge and nuclear mass, of neutron-to-proton ratio, and of angular momentum. The tour to the limits is not only a quest for new, exciting phenomena, but the new data are expected, as well, to bring qualitatively new information about the fundamental properties of the nucleonic many-body system, the nature of the nuclear interaction, and nucleonic correlations at various energy-distance scales. In this series of lectures, current developments in nuclear structure at the limits are discussed from a theoretical perspective, mainly concentrating on medium-mass and heavy nuclei.

  4. Penrose Limits and Spacetime Singularities

    CERN Document Server

    Blau, Matthias; O'Loughlin, M; Papadopoulos, G; Blau, Matthias; Borunda, Monica; Loughlin, Martin O'; Papadopoulos, George

    2003-01-01

    We give a covariant characterisation of the Penrose plane wave limit: the plane wave profile matrix $A(u)$ is the restriction of the null geodesic deviation matrix (curvature tensor) of the original spacetime metric to the null geodesic, evaluated in a comoving frame. We also consider the Penrose limits of spacetime singularities and show that for a large class of black hole, cosmological and null singularities (of Szekeres-Iyers ``power-law type''), including those of the FRW and Schwarzschild metrics, the result is a singular homogeneous plane wave with profile $A(u)\\sim u^{-2}$, the scale invariance of the latter reflecting the power-law behaviour of the singularities.

  5. A Randomized Central Limit Theorem

    Science.gov (United States)

    Eliazar, Iddo; Klafter, Joseph

    2010-05-01

    The Central Limit Theorem (CLT), one of the most elemental pillars of Probability Theory and Statistical Physics, asserts that: the universal probability law of large aggregates of independent and identically distributed random summands with zero mean and finite variance, scaled by the square root of the aggregate-size (√{n}), is Gaussian. The scaling scheme of the CLT is deterministic and uniform - scaling all aggregate-summands by the common and deterministic factor √{n}. This Letter considers scaling schemes which are stochastic and non-uniform, and presents a "Randomized Central Limit Theorem" (RCLT): we establish a class of random scaling schemes which yields universal probability laws of large aggregates of independent and identically distributed random summands. The RCLT universal probability laws, in turn, are the one-sided and the symmetric Lévy laws.

  6. A Randomized Central Limit Theorem

    International Nuclear Information System (INIS)

    The Central Limit Theorem (CLT), one of the most elemental pillars of Probability Theory and Statistical Physics, asserts that: the universal probability law of large aggregates of independent and identically distributed random summands with zero mean and finite variance, scaled by the square root of the aggregate-size (√(n)), is Gaussian. The scaling scheme of the CLT is deterministic and uniform - scaling all aggregate-summands by the common and deterministic factor √(n). This Letter considers scaling schemes which are stochastic and non-uniform, and presents a 'Randomized Central Limit Theorem' (RCLT): we establish a class of random scaling schemes which yields universal probability laws of large aggregates of independent and identically distributed random summands. The RCLT universal probability laws, in turn, are the one-sided and the symmetric Levy laws.

  7. Quantum Diffusion-Limited Aggregation

    CERN Document Server

    Johnson, David B

    2011-01-01

    Though classical random walks have been studied for many years, research concerning their quantum analogues, quantum random walks, has only come about recently. Numerous simulations of both types of walks have been run and analyzed, and are generally well-understood. Research pertaining to one of the more important properties of classical random walks, namely, their ability to build fractal structures in diffusion-limited aggregation, has been particularly noteworthy. However, only now has research begun in this area in regards to quantum random motion. The study of random walks and the structures they build has various applications in materials science. Since all processes are quantum in nature, it is important to consider the quantum variant of diffusion-limited aggregation. Recognizing that Schr\\"odinger equation and a classical random walk are both diffusion equations, it is possible to connect and compare them. Using similar parameters for both equations, we ran various simulations aggregating particles....

  8. Containing Internal Diffusion Limited Aggregation

    CERN Document Server

    Duminil-Copin, Hugo; Yadin, Ariel; Yehudayoff, Amir

    2011-01-01

    Internal Diffusion Limited Aggregation (IDLA) is a model that describes the growth of a random aggregate of particles from the inside out. Shellef proved that IDLA processes on supercritical percolation clusters of integer-lattices fill Euclidean balls, with high probability. In this article, we complete the picture and prove a limit-shape theorem for IDLA on such percolation clusters, by providing the corresponding upper bound. The technique to prove upper bounds is new and robust: it only requires the existence of a "good" lower bound. Specifically, this way of proving upper bounds on IDLA clusters is more suitable for random environments than previous ways, since it does not harness harmonic measure estimates.

  9. Drivers and Limits for Transport

    DEFF Research Database (Denmark)

    Kristensen, Niels Buus; Nielsen, Thomas A. Sick; Gudmundsson, Henrik; Figueroa, Maria; Siren, Anu; Haustein, Sonja; Møller, Mette; Sigurdardottir, Sigrun B.; Christensen, Linda; Knudsen, Mette Aagaard; Rotger, Gabriel P.; Grunfelder, Julien; Mulalic, Ismir; Pilegaard, Ninette; Madsen, Edith; Abate, Megersa Abera; Kveiborg, Ole

    This report summarizes key outcomes of the study ’Drivers and Limits’ that was supported for the period 2009-2013 by a research grant from the Danish Strategic Research Council. The project investigated - for the empirical context of Denmark - key driving forces behind transport growth, as well as...... the notion of limits to mobility, arising out of system interactions or set by external policy ambitions....

  10. China Rare Earth Holdings Limited

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    China Rare Earth Holdings Limited is a large trans-area corporation and a public company listed in Hong Kong Stock Exchange (Name: China Rare Earth, Code: 0769), with headquarter in Hong Kong. Located on the bank of beautiful Taihu Lake, the subsidiary in Yinxing covers area of 200,000 m2. It has nearly 1,000 employees, 30% of whom are technical staffs. After self-administration and effort, the company passed ISO 9001: 2000 and ISO 14000 Certificaitons.

  11. Tiling Spaces are Inverse Limits

    OpenAIRE

    Sadun, Lorenzo

    2002-01-01

    Let M be an arbitrary Riemannian homogeneous space, and let Omega be a space of tilings of M, with finite local complexity (relative to some symmetry group Gamma) and closed in the natural topology. Then Omega is the inverse limit of a sequence of compact finite-dimensional branched manifolds. The branched manifolds are (finite) unions of cells, constructed from the tiles themselves and the group Gamma. This result extends previous results of Anderson and Putnam, of Ormes, Radin and Sadun, of...

  12. Computation Beyond the Turing Limit

    Science.gov (United States)

    Siegelmann, Hava T.

    1995-04-01

    Extensive efforts have been made to prove the Church-Turing thesis, which suggests that all realizable dynamical and physical systems cannot be more powerful than classical models of computation. A simply described but highly chaotic dynamical system called the analog shift map is presented here, which has computational power beyond the Turing limit (super-Turing); it computes exactly like neural networks and analog machines. This dynamical system is conjectured to describe natural physical phenomena.

  13. Goniometry in limited joint mobility

    OpenAIRE

    Gopinath, S.; Manoj, K.; Rubiya

    2012-01-01

    Aim: To study about the utility of goniometry in screening for limited joint mobility (LJM) in patients attending a secondary level Diabetic Clinic. Materials and Methods: Randomly selected data of 100 patients attending a secondary level diabetic clinic without any complications were used. Baseline neuropathy assessments, namely monofilament and biothesiometry were done. Range of movement around the ankle joint and 1 st metatarsal joint was done using goniometry. Both the results were compar...

  14. Summary of Dissolved Concentration Limits

    Energy Technology Data Exchange (ETDEWEB)

    Yueting Chen

    2001-06-11

    According to the Technical Work Plan titled Technical Work Plan for Waste Form Degradation Process Model Report for SR (CRWMS M&O 2000a), the purpose of this study is to perform abstractions on solubility limits of radioactive elements based on the process-level information and thermodynamic databases provided by Natural Environment Program Operations (NEPO) and Waste Package Operations (WPO). The scope of this analysis is to produce solubility limits as functions, distributions, or constants for all transported radioactive elements identified by the Performance Assessment Operations (PAO) radioisotope screening. Results from an expert elicitation for solubility limits of most radioactive elements were used in the previous Total System Performance Assessments (TSPAs). However, the elicitation conducted in 1993 does not meet the criteria set forth by the U.S. Nuclear Regulatory Commission (NRC) due to lack of documentation and traceability (Kotra et al. 1996, Section 3). Therefore, at the Waste Form Abstraction Workshop held on February 2-4, 1999, at Albuquerque, New Mexico, the Yucca Mountain Site Characterization Project (YMP) decided to develop geochemical models to study solubility for the proposed Monitored Geologic Repository. WPO/NEPO is to develop process-level solubility models, including review and compilation of relevant thermodynamic data. PAO's responsibility is to perform abstractions based on the process models and chemical conditions and to produce solubility distributions or response surfaces applicable to the proposed repository. The results of this analysis and conceptual model will feed the performance assessment for Total System Performance Assessment--Site Recommendation (TSPA-SR) and Total System Performance Assessment--License Application (TSPA-LA), and to the Waste Form Degradation Process Model Report section on concentration limits.

  15. Problems of anthropogenic tritium limitation

    Directory of Open Access Journals (Sweden)

    Kochetkov О.A.

    2013-12-01

    Full Text Available This article contains the current situation in respect to the environmental concentrations of anthropogenic and natural tritium. There are presented and analyzed domestic standards for НТО of all Radiation Safety Standards (NRB, as well as the regulations analyzed for tritium in drinking water taken in other countries today. This article deals with the experience of limitation of tritium and focuses on the main problem of rationing of tritium — rationing of organically bound tritium.

  16. BEYOND THE LIMITS OF CRISIS

    Directory of Open Access Journals (Sweden)

    Eduard Ionescu

    2013-11-01

    Full Text Available The recurrence of economic crises serves to illustrate the limits of neoclassical economics and the contemporary established models. The study of complex systems, evolutionary economics and interdisciplinary research offers the possibility of new developments. The concept of emergence represents an insightful argument against the well-planned and ordered nature of the social sciences universe. Complex systems research represents the viable alternative for sustainable growth in the following decades.

  17. Axions - Motivation, limits and searches

    OpenAIRE

    Raffelt, Georg G.

    2006-01-01

    The axion solution of the strong CP problem provides a number of possible windows to physics beyond the standard model, notably in the form of searches for solar axions and for galactic axion dark matter, but in a broader context also inspires searches for axion-like particles in pure laboratory experiments. We briefly review the motivation for axions, astrophysical limits, their possible cosmological role, and current searches for axions and axion-like particles.

  18. Limit laws for exponential families

    OpenAIRE

    Balkema, August A.; Klüppelberg, Claudia; Resnick, Sidney I.

    1999-01-01

    For a real random variable [math] with distribution function [math] , define ¶ [math] ¶ The distribution [math] generates a natural exponential family of distribution functions [math] , where ¶ [math] ¶ We study the asymptotic behaviour of the distribution functions [math] as [math] increases to [math] . If [math] then [math] pointwise on [math] . It may still be possible to obtain a non-degenerate weak limit law [math] by choosing suitable scaling and centring constants [math] an...

  19. Possibilities and limitations of computers

    Energy Technology Data Exchange (ETDEWEB)

    Birnbaum, J.S.

    1983-04-01

    The author analyses the trends towards miniaturisation and faster execution, man machine interface adaptation, architectural styling, artificial intelligence and software engineering. Logic and memory developments are expected to continue at the same pace for the ensuing decade. The limitations of architecture and artificial intelligence are not physical in nature, and the main obstacle to hardware and software progress arises from the complications introduced by design hypotheses over the past 30 years.

  20. Protection limits on free speech

    Institute of Scientific and Technical Information of China (English)

    李敏

    2014-01-01

    Freedom of speech is one of the basic rights of citizens should receive broad protection, but in the real context of China under what kind of speech can be protected and be restricted, how to grasp between state power and free speech limit is a question worth considering. People tend to ignore the freedom of speech and its function, so that some of the rhetoric cannot be demonstrated in the open debates.

  1. Fiscal Limits in Advanced Economies

    OpenAIRE

    Eric M. Leeper; Walker, Todd B

    2011-01-01

    Aging populations in advanced economies are placing ever-increasing demands on government spending in the form of old-age benefits. Economies that have promised substantially more benefits than they have made provision to finance are heading into a prolonged era of fiscal stress. Unresolved fiscal stress raises the possibility that the economies will hit their fiscal limits where taxes and spending no longer adjust to stabilize debt. In such economies, monetary policy may lose its ability to ...

  2. Liquid-Bridge Breaking Limits

    Science.gov (United States)

    Macner, Ashley; Steen, Paul

    2011-11-01

    Wet adhesion by liquid bridges in large arrays shows promise for use in lightweight, controllable on-demand devices. Applications include grab/release of wafer substrates, transport of micron-sized tiles for use in 3D printing and micro-dosing of personalized pharmaceutical drugs. By wetting and spreading, a drop can form a bridge and thereby ``grab'' a nearby solid substrate. By volume decrease or extension, the bridge can break. The breaking limit corresponds to bridge instability which can be predicted, knowing the static mechanical response of the bridge. Mechanical behaviors include force-volume (FV), pressure-volume (pV) and force-length (FL) responses. Instability crucially depends on the mode of failure - failure under constant-force or constant length are typical cases. We study single bridge equilibria for their breaking limits. FV diagrams for the pin-pin equal and pin-pin unequal radii boundary conditions for different bridge heights are measured in the laboratory. The FL response in the case of pin-pin equal radii is also measured. Results are compared to predictions of static theory. Static results are then used to compare to dynamical sequences where volume is driven quasistatically by syringe or an electro-osmotic pump. As the breaking limit is approached, the shape deformation accelerates leading to non-equilibrium shapes not captured by the static analysis.

  3. Workshop on confidence limits. Proceedings

    International Nuclear Information System (INIS)

    The First Workshop on Confidence Limits was held at CERN on 17-18 January 2000. It was devoted to the problem of setting confidence limits in difficult cases: number of observed events is small or zero, background is larger than signal, background not well known, and measurements near a physical boundary. Among the many examples in high-energy physics are searches for the Higgs, searches for neutrino oscillations, Bs mixing, SUSY, compositeness, neutrino masses, and dark matter. Several different methods are on the market: the CLs methods used by the LEP Higgs searches; Bayesian methods; Feldman-Cousins and modifications thereof; empirical and combined methods. The Workshop generated considerable interest, and attendance was finally limited by the seating capacity of the CERN Council Chamber where all the sessions took place. These proceedings contain all the papers presented, as well as the full text of the discussions after each paper and of course the last session which was a discussion session. The list of participants and the 'required reading', which was expected to be part of the prior knowledge of all participants, are also included. (orig.)

  4. Application of fault current limiters

    Energy Technology Data Exchange (ETDEWEB)

    Neumann, A.

    2007-11-30

    This report presents the results of a study commissioned by the Department for Business, Enterprise and Industry (BERR; formerly the Department of Trade and Industry) into the application of fault current limiters in the UK. The study reviewed the current state of fault current limiter (FCL) technology and regulatory position in relation to all types of current limiters. It identified significant research and development work with respect to medium voltage FCLs and a move to high voltage. Appropriate FCL technologies being developed include: solid state breakers; superconducting FCLs (including superconducting transformers); magnetic FCLs; and active network controllers. Commercialisation of these products depends on successful field tests and experience, plus material development in the case of high temperature superconducting FCL technologies. The report describes FCL techniques, the current state of FCL technologies, practical applications and future outlook for FCL technologies, distribution fault level analysis and an outline methodology for assessing the materiality of the fault level problem. A roadmap is presented that provides an 'action agenda' to advance the fault level issues associated with low carbon networks.

  5. Casimir effect: The classical limit

    International Nuclear Information System (INIS)

    We analyze the high temperature (or classical) limit of the Casimir effect. A useful quantity which arises naturally in our discussion is the 'relative Casimir energy', which we define for a configuration of disjoint conducting boundaries of arbitrary shapes, as the difference of Casimir energies between the given configuration and a configuration with the same boundaries infinitely far apart. Using path integration techniques, we show that the relative Casimir energy vanishes exponentially fast in temperature. This is consistent with a simple physical argument based on Kirchhoff's law. As a result the 'relative Casimir entropy', which we define in an obviously analogous manner, tends, in the classical limit, to a finite asymptotic value which depends only on the geometry of the boundaries. Thus the Casimir force between disjoint pieces of the boundary, in the classical limit, is entropy driven and is governed by a dimensionless number characterizing the geometry of the cavity. Contributions to the Casimir thermodynamical quantities due to each individual connected component of the boundary exhibit logarithmic deviations in temperature from the behavior just described. These logarithmic deviations seem to arise due to our difficulty to separate the Casimir energy (and the other thermodynamical quantities) from the 'electromagnetic' self-energy of each of the connected components of the boundary in a well defined manner. Our approach to the Casimir effect is not to impose sharp boundary conditions on the fluctuating field, but rather take into consideration its interaction with the plasma of 'charge carriers' in the boundary, with the plasma frequency playing the role of a physical UV cutoff. This also allows us to analyze deviations from a perfect conductor behavior

  6. Limits to the growth debate

    Energy Technology Data Exchange (ETDEWEB)

    Gordon, L.

    The first two major studies sponsored by the club of Rome were the report of the Meadows team at MIT, The Limits to Growth, published in 1972, and the Mesarovic and Pestel report, Mankind at the Turning Point, published in 1974. When the Club of Rome met in Philadelphia in April of 1976, its pronouncements reflected a frame of mind quite different from that of 1972. Recently, Herman Kahn and his colleagues at the Hudson Institute have published The Next 200 Years, a book evidently inspired as much by antagonism to the limits-to-growth school of thought as by affirmative faith in its own vision of technological optimism. The author discusses the content of the studies and summarizes his own position in four areas. (1) While no trend of growth of anything can continue indefinitely in the real world, there are not global physical limits to economic growth within a time frame susceptible to plausible foresight or relevant to policy making. (2) In some world regions, notably South Asia and tropical Africa, population growth rates do indeed threaten to create a kind of Malthusian trap, and the rapid reduction of fertility is critically important to their development prospects and urgent in time. (3) For other parts of the world, both rates and directions of growth will be more influenced by changes in preferences for consumption and in attitudes toward production than by physical constraints, although higher energy costs and environmental pressures will also be important influences in generating such changes in growth patterns. (4) Probable changes in directions of growth will generate new and important issues in international economic and political relations, with both dangers and opportunities for the evolving world order. (MCW)

  7. Flooding-limited thermal mixing

    International Nuclear Information System (INIS)

    In this paper stratification in the cold leg due to high-pressure injection in a stagnated loop of a pressurized water reactor is considered. The working hypothesis is that at high injection Froude numbers, the extent of mixing approaches a limit controlled only by the flooding condition at the cold-leg exit. Experimental data available support this hypothesis. Predictions for reactor conditions indicate a stratification of ∼ 40 degrees C. As a consequence, the downcomer plume would be rather weak (with a low Froude number) and would be expected to decay quickly

  8. The Limit of Large Vessels

    Institute of Scientific and Technical Information of China (English)

    Yang Peiju

    2011-01-01

    On Feb 21(st),the industry was shocked by the news that AP Moller-Maersk placed an order of 10 container ships of 18,000 TEU with the South Korean ship yards.The order brings the development of large vessels to a new climax and at the same time puts forward a series of research subjects to the industry,such as what is the limit for the development of large vessels,whether ship safety can be guaranteed,and etc.

  9. Taming Limits with Approximate Networking

    OpenAIRE

    Qadir, Junaid; Sathiaseelan, Arjuna; Wang, Liang; Crowcroft, Jon

    2016-01-01

    Internet is the linchpin of modern society, which the various threads of modern life weave around. But being a part of the bigger energy-guzzling industrial economy, it is vulnerable to disruption. It is widely believed that our society is exhausting its vital resources to meet our energy requirements, and the cheap fossil fuel fiesta will soon abate as we cross the tipping point of global oil production. We will then enter the long arc of scarcity, constraints, and limits---a post-peak "long...

  10. Neonatal anesthesia with limited resources.

    Science.gov (United States)

    Bösenberg, Adrian T

    2014-01-01

    Neonates are the most vulnerable age group in terms of anesthetic risk and perioperative mortality, especially in the developing world. Prematurity, malnutrition, delays in presentation, and sepsis contribute to this risk. Lack of healthcare workers, poorly maintained equipment, limited drug supplies, absence of postoperative intensive care, unreliable water supplies, or electricity are further contributory factors. Trained anesthesiologists with the skills required for pediatric and neonatal anesthesia as well as basic monitoring equipment such as pulse oximetry will go a long way to improve the unacceptably high anesthetic mortality. PMID:24251423

  11. Conventional colonoscopy: Technique, indications, limits

    International Nuclear Information System (INIS)

    Colonoscopy has long been the gold standard for the diagnosis of colonic diseases. Recently, with the advent of CT colonografy, new alternatives seem to appear on the horizon, which seem to finally overcome some of colonoscopy's drawbacks like procedure related pain and discomfort during the examination. Polyp miss rate and the fact that not always the caecum can be reached are also the basis of debate. This article gives an overview about current technique, indications and limitations of diagnostic colonoscopy as well as a potential prospect for the future, discussing novel imaging technologies ranging from magnification endoscopy to virtual histopathology

  12. CSS3 pushing the limits

    CERN Document Server

    Greig, Stephen

    2013-01-01

    Push CSS3 and your design skills to the limit-and beyond! Representing an evolutionary leap forward for CSS, CSS3 is chock-full of new capabilities that dramatically expand the boundaries of what a styling language can do. But many of those new features remain undocumented, making it difficult to learn what they are and how to use them to create the sophisticated sites and web apps clients demand and users have grown to expect. Until now. This book introduces you to all of CSS3's new and advanced features, and, with the help of dozens of real-world examples and live

  13. Thermodynamic effects on limited cavitation

    International Nuclear Information System (INIS)

    Experimental and theoretical data are presented for limited cavitation on hemispherical-nosed bodies in water and Freon 113. The experiments were conducted with 0.25 inch and 0.50 inch diameter models over a temperature range and velocity range of 80-260 deg F and 40-130fps, respectively. In general the experimental data do not display the decrease in cavitation number with temperature as predicted by the theory. It is feld that at least part of the differences between experimental and theoretical data are due to the effects of non condensable gas, laminar separation and boundary layer transition

  14. Inhomogeneous diffusion-limited aggregation

    Science.gov (United States)

    Selinger, Robin Blumberg; Nittmann, Johann; Stanley, H. E.

    1989-01-01

    It is demonstrated here that inhomogeneous diffusion-limited aggregation (DLA) model can be used to simulate viscous fingering in a medium with inhomogeneous permeability and homogeneous porosity. The medium consists of a pipe-pore square-lattice network in which all pores have equal volume and the pipes have negligible volume. It is shown that fluctuations in a DLA-based growth process may be tuned by noise reduction, and that fluctuations in the velocity of the moving interface are multiplicative in form.

  15. Food irradiation, profits and limitations

    International Nuclear Information System (INIS)

    The utility of the irradiation to overcome diverse problems of lost nutritious, it has been demonstrated in multiple investigation works, that its have confirmed the value and the inoculation of the irradiated foods. The quantity of energy applied to each food, is in function of the wanted effect. In this document a guide with respect to the practical application and the utility of the irradiation process in different foods, as well as the suggested dose average is shown. Among the limitations of the use of this technology, its are the costs and not being able to apply it to some fresh foods. (Author)

  16. 36 CFR 4.21 - Speed limits.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Speed limits. 4.21 Section 4... TRAFFIC SAFETY § 4.21 Speed limits. (a) Park area speed limits are as follows: (1) 15 miles per hour... superintendent may designate a different speed limit upon any park road when a speed limit set forth in...

  17. 40 CFR 158.350 - Certified limits.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Certified limits. 158.350 Section 158... REQUIREMENTS FOR PESTICIDES Product Chemistry § 158.350 Certified limits. The applicant must propose certified limits for the ingredients in the product. Certified limits become legally binding limits upon...

  18. Collider limits on leptophilic interactions

    International Nuclear Information System (INIS)

    In order to observe leptophilic interactions at the LHC we must require at least four leptons, which may be in particular neutrinos, in the final state. If they are mediated by a resonance in the di-leptonic channel, this must be of spin 1 to be produced through a renormalizable coupling. We study the LHC reach for such a vector boson allowing for arbitrary couplings, what in practice means for arbitrary couplings to muons because lepton flavor violating couplings are constrained by rare processes, couplings to electrons by LEP and LHC is not sensitive to final states involving taus in this case. This makes the ILC complementary as it will provide the best limits on Z' couplings to tau leptons. A prominent example is the case of the anomaly-free Z' coupling to the muon minus tau lepton number Lμ-Lτ. If no departure from the Standard Model is observed at the LHC, the most stringent bounds on this vector boson are provided from events with only three charged leptons plus missing energy. Masses of the order of 1 TeV can be probed at the high-luminosity phase of the LHC for Z' couplings of order one. Generic four-lepton operators parametrizing leptophilic interactions can be also restricted using three and four (or two at the ILC) charged lepton samples, but the corresponding limits are marginal, if meaningful, because the resonant behavior appears to be essential for the signal to be significant.

  19. Cosmology in the Newtonian limit

    CERN Document Server

    Bertello, Ugo

    2012-01-01

    Numerical N-body simulations of large scale structure formation in the universe are based on Newtonian gravity. However, according to our current understanding, the most correct theory of gravity is general relativity. It is therefore important to understand which degrees of freedom and which features are lost when the relativistic universe is approximated, or rather replaced, by a Newtonian one. This is the main purpose of our investigation. We first define Newtonian cosmology and we give an overview on general relativity, both in its standard and covariant formulations. We show how the two theories deal with inhomogeneous cosmological models and we introduce the backreaction conjecture. Then we review on how Newtonian gravity and general relativity relate to each other in the fully non-linear regime. For this purpose we discuss frame theory. We carry out the same investigation also in the weak-field, small-velocity limit of general relativity, and we derive the Newtonian limit resorting to the framework of ...

  20. Energy-limited escape revised

    CERN Document Server

    Salz, M; Czesla, S; Schmitt, J H M M

    2016-01-01

    Gas planets in close proximity to their host stars experience photoevaporative mass loss. The energy-limited escape concept is generally used to derive estimates for the planetary mass-loss rates. Our photoionization hydrodynamics simulations of the thermospheres of hot gas planets show that the energy-limited escape concept is valid only for planets with a gravitational potential lower than $\\log_\\mathrm{10}\\left( -\\Phi_{\\mathrm{G}}\\right) < 13.11~$erg$\\,$g$^{-1}$ because in these planets the radiative energy input is efficiently used to drive the planetary wind. Massive and compact planets with $\\log_\\mathrm{10}\\left( -\\Phi_{\\mathrm{G}}\\right) \\gtrsim 13.6~$erg$\\,$g$^{-1}$ exhibit more tightly bound atmospheres in which the complete radiative energy input is re-emitted through hydrogen Ly$\\alpha$ and free-free emission. These planets therefore host hydrodynamically stable thermospheres. Between these two extremes the strength of the planetary winds rapidly declines as a result of a decreasing heating eff...

  1. 24 CFR 585.302 - Award limits.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Award limits. 585.302 Section 585... DEVELOPMENT COMMUNITY FACILITIES YOUTHBUILD PROGRAM Youthbuild Implementation Grants § 585.302 Award limits... than the specified limit....

  2. Mathematical methods for hydrodynamic limits

    CERN Document Server

    Masi, Anna

    1991-01-01

    Entropy inequalities, correlation functions, couplings between stochastic processes are powerful techniques which have been extensively used to give arigorous foundation to the theory of complex, many component systems and to its many applications in a variety of fields as physics, biology, population dynamics, economics, ... The purpose of the book is to make theseand other mathematical methods accessible to readers with a limited background in probability and physics by examining in detail a few models where the techniques emerge clearly, while extra difficulties arekept to a minimum. Lanford's method and its extension to the hierarchy of equations for the truncated correlation functions, the v-functions, are presented and applied to prove the validity of macroscopic equations forstochastic particle systems which are perturbations of the independent and of the symmetric simple exclusion processes. Entropy inequalities are discussed in the frame of the Guo-Papanicolaou-Varadhan technique and of theKipnis-Oll...

  3. Limitations of bootstrap current models

    International Nuclear Information System (INIS)

    We assess the accuracy and limitations of two analytic models of the tokamak bootstrap current: (1) the well-known Sauter model (1999 Phys. Plasmas 6 2834, 2002 Phys. Plasmas 9 5140) and (2) a recent modification of the Sauter model by Koh et al (2012 Phys. Plasmas 19 072505). For this study, we use simulations from the first-principles kinetic code NEO as the baseline to which the models are compared. Tests are performed using both theoretical parameter scans as well as core-to-edge scans of real DIII-D and NSTX plasma profiles. The effects of extreme aspect ratio, large impurity fraction, energetic particles, and high collisionality are studied. In particular, the error in neglecting cross-species collisional coupling—an approximation inherent to both analytic models—is quantified. Furthermore, the implications of the corrections from kinetic NEO simulations on MHD equilibrium reconstructions is studied via integrated modeling with kinetic EFIT. (paper)

  4. Pericytes limit tumor cell metastasis

    DEFF Research Database (Denmark)

    Xian, Xiaojie; Håkansson, Joakim; Ståhlberg, Anders;

    2006-01-01

    Previously we observed that neural cell adhesion molecule (NCAM) deficiency in beta tumor cells facilitates metastasis into distant organs and local lymph nodes. Here, we show that NCAM-deficient beta cell tumors grew leaky blood vessels with perturbed pericyte-endothelial cell-cell interactions...... and deficient perivascular deposition of ECM components. Conversely, tumor cell expression of NCAM in a fibrosarcoma model (T241) improved pericyte recruitment and increased perivascular deposition of ECM molecules. Together, these findings suggest that NCAM may limit tumor cell metastasis by...... stabilizing the microvessel wall. To directly address whether pericyte dysfunction increases the metastatic potential of solid tumors, we studied beta cell tumorigenesis in primary pericyte-deficient Pdgfb(ret/ret) mice. This resulted in beta tumor cell metastases in distant organs and local lymph nodes...

  5. Goniometry in limited joint mobility

    Directory of Open Access Journals (Sweden)

    S Gopinath

    2012-01-01

    Full Text Available Aim: To study about the utility of goniometry in screening for limited joint mobility (LJM in patients attending a secondary level Diabetic Clinic. Materials and Methods: Randomly selected data of 100 patients attending a secondary level diabetic clinic without any complications were used. Baseline neuropathy assessments, namely monofilament and biothesiometry were done. Range of movement around the ankle joint and 1 st metatarsal joint was done using goniometry. Both the results were compared. Inclusion Criteria: Selected 100 patients attending a secondary level diabetic clinic and on regular follow-up were included in the study. Exclusion Criteria: Sick patients requiring parenteral feeds, IV antibiotics, co-morbid conditions such as microvascular complication, autonomic gastroparesis, and diabetic foot infections were excluded from the study. Conclusion: Goniometric screening for LJM is a cheap and effective screening tool for detecting early structural deformity producing a higher plantar pressure and ulcer, and thereby preventing them at early stage.

  6. Material selection for TFTR limiters

    International Nuclear Information System (INIS)

    The requirements for the material to be used as the first surface of limiters in TFTR are that it: (1) withstand a heat flux of 1 kw/cm2 for a pulse length of 1.5s and a duty cycle of 1/200 for 105 cycles, (2) withstand the thermal and electro-magnetic loads from 104 plasma current disruptions lasting about 200 μs, (3) generate impurities at a rate low enough to meet impurity control requirements (which depend on the atomic number of the material) for TFTR, and (4) have tritium retention characteristics consistent with tritium inventory requirements for TFTR. An extensive set of material tests using electron beams, neutral beams, and plasma bombardment have been carried out to identify materials which can meet the thermal requirements of the above

  7. Casimir Effect - The Classical Limit

    International Nuclear Information System (INIS)

    The temperature dependence of the Casimir effect for the radiation field confined between two conducting plates is analysed; The Casimir energy is shown to decline exponentially with temperature while the Casimir entropy which is defined in the text is shown to approach a limit which depends only on the geometry of the constraining plates. The result is shown to hold, for a scalar field, for arbitrary geometry. The high temperature (T) expansion is shown to be ''robust'', i.e. it does not have any nonvanishing correction to the ''classical' result where the latter is defined by the validity of the Rayleigh - Jeans law. We show that validity of the Rayleigh - Jeans law implies the vanishing of the Casimir energy, hence the high temperature Casimir force, for a wide variety of geometries, is purely entropic

  8. THE LIMITS OF ESP TESTS

    Directory of Open Access Journals (Sweden)

    Norica-Felicia BUCUR

    2015-07-01

    Full Text Available Global market forces have determined not only higher education institutions all over the world to include ESP courses in their curriculum to enhance their students’ future employability, but also public and private organisations to offer their employees the opportunity to attend ESP courses in order to meet the continuously growing ESP needs. From this perspective, ESP compentence could become a subcomponent of one of the key competences for lifelong learning, communication in foreign languages. Therefore assessing ESP competence seems to acquire paramount importance since stakeholders need accurate information about the ESP learners’ abilities to cope with specific language tasks. This article offers a concise overview of the principles and practices of ESP assessment, a detailed description of the features of ESP tests, while focusing particularly on the limits of ESP tests in order to identify possible solutions to overcome them.

  9. Proposition Algebra with Projective Limits

    CERN Document Server

    Bergstra, J A

    2008-01-01

    Sequential logic deviates from propositional logic by taking into account that atomic propositions yield different Boolean values at different times during the sequential evaluation of a single proposition. Reactive valuations capture this dynamics of a proposition's environment. This logic is phrased as an equationally specified algebra rather than in the form of proof rules. It is strictly more general than Boolean algebra to the extent that the classical connectives fail to be expressively complete in the sequential case. The proposition algebra PRA is developed in a fashion similar to the process algebra ACP and the program algebra PGA via an algebraic specification which has a meaningful initial algebra for which a range of courser congruences are considered important as well. In addition infinite objects (that is propositions, processes and programs respectively) are preferably dealt with by means of an inverse limit construction which allows the transfer of knowledge concerning finite objects to facts ...

  10. Extremal Limits and Kerr Spacetime

    CERN Document Server

    Pradhan, Parthapratim

    2013-01-01

    We study Innermost Stable Circular Orbits (ISCO) in extremal Kerr spacetime which lie close (in terms of the radial coordinate) to the event horizon and compare these with similar orbits in the near-extremal situation. Extremization of the effective potential for timelike circular orbits shows the existence of a stable circular geodesics in the extremal spacetime, precisely {\\it on} the event horizon in terms of the radial coordinate. This type of geodesics is unstable in the corresponding near-extremal spacetime as we show here, testifying to differences between the extremal limit of a generic Kerr spacetime and the exactly extremal geometry. Another aspect of the extremization of the effective potential for null circular orbits shows the existence of an unstable circular geodesic due to the axisymmetry of the spacetime in the extremal Kerr black hole. We attempt to relate this to the fact that the extremal Kerr black hole spacetime possesses no outer trapped surface.

  11. Prospective Optimization with Limited Resources.

    Science.gov (United States)

    Snider, Joseph; Lee, Dongpyo; Poizner, Howard; Gepshtein, Sergei

    2015-09-01

    The future is uncertain because some forthcoming events are unpredictable and also because our ability to foresee the myriad consequences of our own actions is limited. Here we studied how humans select actions under such extrinsic and intrinsic uncertainty, in view of an exponentially expanding number of prospects on a branching multivalued visual stimulus. A triangular grid of disks of different sizes scrolled down a touchscreen at a variable speed. The larger disks represented larger rewards. The task was to maximize the cumulative reward by touching one disk at a time in a rapid sequence, forming an upward path across the grid, while every step along the path constrained the part of the grid accessible in the future. This task captured some of the complexity of natural behavior in the risky and dynamic world, where ongoing decisions alter the landscape of future rewards. By comparing human behavior with behavior of ideal actors, we identified the strategies used by humans in terms of how far into the future they looked (their "depth of computation") and how often they attempted to incorporate new information about the future rewards (their "recalculation period"). We found that, for a given task difficulty, humans traded off their depth of computation for the recalculation period. The form of this tradeoff was consistent with a complete, brute-force exploration of all possible paths up to a resource-limited finite depth. A step-by-step analysis of the human behavior revealed that participants took into account very fine distinctions between the future rewards and that they abstained from some simple heuristics in assessment of the alternative paths, such as seeking only the largest disks or avoiding the smaller disks. The participants preferred to reduce their depth of computation or increase the recalculation period rather than sacrifice the precision of computation. PMID:26367309

  12. Prospective Optimization with Limited Resources.

    Directory of Open Access Journals (Sweden)

    Joseph Snider

    2015-09-01

    Full Text Available The future is uncertain because some forthcoming events are unpredictable and also because our ability to foresee the myriad consequences of our own actions is limited. Here we studied how humans select actions under such extrinsic and intrinsic uncertainty, in view of an exponentially expanding number of prospects on a branching multivalued visual stimulus. A triangular grid of disks of different sizes scrolled down a touchscreen at a variable speed. The larger disks represented larger rewards. The task was to maximize the cumulative reward by touching one disk at a time in a rapid sequence, forming an upward path across the grid, while every step along the path constrained the part of the grid accessible in the future. This task captured some of the complexity of natural behavior in the risky and dynamic world, where ongoing decisions alter the landscape of future rewards. By comparing human behavior with behavior of ideal actors, we identified the strategies used by humans in terms of how far into the future they looked (their "depth of computation" and how often they attempted to incorporate new information about the future rewards (their "recalculation period". We found that, for a given task difficulty, humans traded off their depth of computation for the recalculation period. The form of this tradeoff was consistent with a complete, brute-force exploration of all possible paths up to a resource-limited finite depth. A step-by-step analysis of the human behavior revealed that participants took into account very fine distinctions between the future rewards and that they abstained from some simple heuristics in assessment of the alternative paths, such as seeking only the largest disks or avoiding the smaller disks. The participants preferred to reduce their depth of computation or increase the recalculation period rather than sacrifice the precision of computation.

  13. Collider limits on leptophilic interactions

    Energy Technology Data Exchange (ETDEWEB)

    Aguila, Francisco del; Yamamoto, Yasuhiro [Granada Univ. (Spain). CAFPE; Granada Univ. (Spain). Dept. de Fisica Teorica y del Cosmos; Chala, Mikael [Granada Univ. (Spain). CAFPE; Granada Univ. (Spain). Dept. de Fisica Teorica y del Cosmos; Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Santiago, Jose [Granada Univ. (Spain). CAFPE; Granada Univ. (Spain). Dept. de Fisica Teorica y del Cosmos; European Organization for Nuclear Research (CERN), Geneva (Switzerland)

    2014-11-15

    In order to observe leptophilic interactions at the LHC we must require at least four leptons, which may be in particular neutrinos, in the final state. If they are mediated by a resonance in the di-leptonic channel, this must be of spin 1 to be produced through a renormalizable coupling. We study the LHC reach for such a vector boson allowing for arbitrary couplings, what in practice means for arbitrary couplings to muons because lepton flavor violating couplings are constrained by rare processes, couplings to electrons by LEP and LHC is not sensitive to final states involving taus in this case. This makes the ILC complementary as it will provide the best limits on Z' couplings to tau leptons. A prominent example is the case of the anomaly-free Z' coupling to the muon minus tau lepton number L{sub μ}-L{sub τ}. If no departure from the Standard Model is observed at the LHC, the most stringent bounds on this vector boson are provided from events with only three charged leptons plus missing energy. Masses of the order of 1 TeV can be probed at the high-luminosity phase of the LHC for Z' couplings of order one. Generic four-lepton operators parametrizing leptophilic interactions can be also restricted using three and four (or two at the ILC) charged lepton samples, but the corresponding limits are marginal, if meaningful, because the resonant behavior appears to be essential for the signal to be significant.

  14. Pure Phase Solubility Limits: LANL

    International Nuclear Information System (INIS)

    The natural and engineered system at Yucca Mountain (YM) defines the site-specific conditions under which one must determine to what extent the engineered and the natural geochemical barriers will prevent the release of radioactive material from the repository. Most important mechanisms for retention or enhancement of radionuclide transport include precipitation or co-precipitation of radionuclide-bearing solid phases (solubility limits), complexation in solution, sorption onto surfaces, colloid formation, and diffusion. There may be many scenarios that could affect the near-field environment, creating chemical conditions more aggressive than the conditions presented by the unperturbed system (such as pH changes beyond the range of 6 to 9 or significant changes in the ionic strength of infiltrated waters). For an extended period of time, the near-field water composition may be quite different and more extreme in pH, ionic strength, and CO2 partial pressure (or carbonate concentration) than waters at some distance from the repository. Reducing conditions, high pH (up to 11), and low carbonate concentration may be present in the near-field after reaction of infiltrating groundwater with engineered barrier systems, such as cementitious materials. In the far-field, conditions are controlled by the rock-mass buffer providing a near-neutral, oxidizing, low-ionic-strength environment that controls radionuclide solubility limits and sorption capacities. There is the need for characterization of variable chemical conditions that affect solubility, speciation, and sorption reactions. Modeling of the groundwater chemistry is required and leads to an understanding of solubility and speciation of the important radionuclides. Because experimental studies cannot be performed under the numerous potential chemical conditions, solubility limitations must rely on geochemical modeling of the radionuclide's chemistry. Fundamental thermodynamic properties, such as solubility products

  15. Changing ideas of global limits.

    Science.gov (United States)

    Goddy, D

    1984-03-01

    In this discussion of changing ideas of global limits, attention is directed to world trade, moral restraint, and the "green revolution." A fresh look at the work of those who first considered population problems, e.gg., Malthur, can help make some sense of the population problems the world faces today. Malthus, writing in the late 1700s, concluded that population multiplies with each generation. He saw that food production was limited by the amount of available cropland and that the more people there are, the less food they will have to eat -- assuming that all available cropland is planted. This grim view of the future led Malthus to oppose government aid to the poor maintaining that such assistance would only encourage poor people to have large families. His solution was "moral restratin," seeing it as the duty of each individual to refrain from marriage until he was able to support his children. At the time this advice seemed cruel and Malthus was bitterly attacked by writers everywhere in Europe. Karl Marx and other ctitics of Malthus believed that poverty was caused by unjust governments and the selfishness of the rich. Marx clamied that the problem was too few jobs rather than too many people. The dire predictions of Malthus were soon forgotten as manufacturing industries began to transform the economies of Western Europe in the 1800s. Along with soaring economic growth came a host of developments that improved people's lives, e.g., better transportation, better sanitiation and nutrition, and better medicine. New inventions helped farmers fo produce more food. Next came the "demographic transition." Population grew quickly in Europe and North America as people became healthier and lived longer. Gradually, people in the industrial nations began deciding to have smaller families to enable them to afford an even higher living standard. By the late 1920s birthrates in Europe and the US had dropped so low that mention of the "population problem" usually referred

  16. Penrose limits versus string expansions

    Energy Technology Data Exchange (ETDEWEB)

    Blau, Matthias; Weiss, Sebastian [Institut de Physique, Universite de Neuchatel, Rue Breguet 1, CH-2000 Neuchatel (Switzerland)

    2008-06-21

    We analyze the relation between two a priori quite different expansions of the string equations of motion and constraints in a general curved background, namely one based on the covariant Penrose-Fermi expansion of the metric G{sub {mu}}{sub {nu}} around a Penrose limit plane wave associated with a null geodesic {gamma} and the other on the Riemann coordinate expansion in the exact metric G{sub {mu}}{sub {nu}} of the string embedding variables around the null geodesic {gamma}. Starting with the observation that there is a formal analogy between the exact string equations in a plane wave and the first-order string equations in a general background, we show that this analogy becomes exact provided that one chooses the background string configuration to be the null geodesic {gamma} itself. We then explore the higher-order correspondence between these two expansions and find that for a general curved background they agree to all orders provided that one works in Fermi coordinates and in the lightcone gauge. Requiring moreover the conformal gauge restricts one to the usual class of (Brinkmann) backgrounds admitting simultaneously the lightcone and the conformal gauge, without further restrictions.

  17. Limited small cell lung cancer

    International Nuclear Information System (INIS)

    This paper assesses the prognosis of patients with limited small cell lung cancer (LSCLC) not achieving complete response (CR) to induction combination chemotherapy (ICC) but who achieve CR after thoracic irradiation (TI). Twenty-four patients had CRs to ICC (CR- ICC) of two cycles of cytoxan, Adriamycin, and vincristine alternating with two cycles of cisplatin with VP-16. Another 24 had CR after consolidation with subsequent T1 (CR-T1): 45 Gy in daily fractions of 2.5 Gy or twice-daily fractions of 1.5 Gy. The CR-ICC and CR-TI patients had similar prognostic factors and treatment. Comparing CR-ICC and CR-TI, survival was 40% versus 26% at 2 years and 35% versus 4% at 5 years (P < .05). There were eight (33%) long-term survivors (≥3 years) in the CR-ICC group versus three (13%) in the CR-TI group. Local control for CR-ICC patients was 59% at 5 years versus 21% for the CR-TI patients (not significant). Freedom from DM for the CR-ICC patients was 41% at 5 years versus 8% for the CR-TI patients (P < .05)

  18. Agriculture: access to technology limited.

    Science.gov (United States)

    1997-01-01

    From country to country and even regionally, the roles of women in agriculture vary, but most of their labor is in unpaid subsistence production and their contributions tend to be underestimated, according to the results of the [UN] Secretary-General's report. Depending on circumstances, they have complementary roles with men, sharing or dividing tasks in the production of crops, care of animals, and forestry management. In sub-Saharan Africa, for example, women contribute 60-80% of labor in food production for both household consumption and sale, while in Malaysia the women account for only 35% of the agricultural labor force, and in Ireland the participation rate is only 10.4%. Although women make this important amount of labor contributions to agricultural production, "development policies tend to favor export crops to earn foreign exchange and the agricultural research tends to address the improvement of production and technologies for commercial production". This results in limited access for women to technical knowledge and innovations, including irrigation, machinery, farming techniques and extension services. This is strengthened by the fact that most of the extension services target farmers who own land and can obtain credit to invest in input and technology. PMID:12293737

  19. Photon and graviton mass limits

    Energy Technology Data Exchange (ETDEWEB)

    Nieto, Michael [Los Alamos National Laboratory; Goldhaber Scharff, Alfred [SUNY

    2008-01-01

    We review past and current studies of possible long-distance, low-frequency deviations from Maxwell electrodynamics and Einstein gravity. Both have passed through three phases: (1) Testing the inverse-square laws of Newton and Coulomb, (2) Seeking a nonzero value for the rest mass of photon or graviton, and (3) Considering more degrees of freedom, allowing mass while preserving gauge or general-coordinate invariance. For electrodynamics there continues to be no sign of any deviation. Since our previous review the lower limit on the photon Compton wavelength (associated with weakening of electromagnetic fields in vacuum over large distance scale) has improved by four orders of magnitude, to about one astronomical unit. Rapid current progress in astronomical observations makes it likely that there will be further advances. These ultimately could yield a bound exceeding galactic dimensions, as has long been contemplated. Meanwhile, for gravity there have been strong arguments about even the concept of a graviton rest mass. At the same time there are striking observations, commonly labeled 'dark matter' and 'dark energy' that some argue imply modified gravity. This makes the questions for gravity much more interesting. For dark matter, which involves increased attraction at large distances, any explanation by modified gravity would be qualitatively different from graviton mass. Because dark energy is associated with reduced attraction at large distances, it might be explained by a graviton-mass-like effect.

  20. IDENTIDADES MASCULINAS: LIMITES E POSSIBILIDADES

    Directory of Open Access Journals (Sweden)

    May-Lin Wang

    2006-06-01

    Full Text Available O presente trabalho toma por base uma abordagem psicossocial para discorrer sobre os limites impostos pelos estereótipos de gênero à construção de uma identidade masculina, em contraposição às possibilidades de subjetivação, num cenário cultural de pluralidade identitária. Ênfase é dada à socialização estereotipada dos meninos, num processo no qual se verifica uma espécie de superposição do contexto socio-histórico em que cresceram os pais àquele no qual o menino é socializado, acentuando determinadas crenças sobre gênero. O modelo tradicional de virilidade, que imperava inquestionável até bem pouco tempo, ignorando as necessidades afetivas e valorizando características como a competitividade, a preocupação com o desempenho, o autoritarismo, a dominação e a opressão, vem sendo questionado como pilar maior da identidade masculina tradicional.

  1. Anisotropic diffusion-limited aggregation.

    Science.gov (United States)

    Popescu, M N; Hentschel, H G E; Family, F

    2004-06-01

    Using stochastic conformal mappings, we study the effects of anisotropic perturbations on diffusion-limited aggregation (DLA) in two dimensions. The harmonic measure of the growth probability for DLA can be conformally mapped onto a constant measure on a unit circle. Here we map m preferred directions for growth to a distribution on the unit circle, which is a periodic function with m peaks in [-pi,pi) such that the angular width sigma of the peak defines the "strength" of anisotropy kappa= sigma(-1) along any of the m chosen directions. The two parameters (m,kappa) map out a parameter space of perturbations that allows a continuous transition from DLA (for small enough kappa ) to m needlelike fingers as kappa--> infinity. We show that at fixed m the effective fractal dimension of the clusters D(m,kappa) obtained from mass-radius scaling decreases with increasing kappa from D(DLA) approximately 1.71 to a value bounded from below by D(min) = 3 / 2. Scaling arguments suggest a specific form for the dependence of the fractal dimension D(m,kappa) on kappa for large kappa which compares favorably with numerical results. PMID:15244564

  2. 45 CFR 3.26 - Speed limit.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Speed limit. 3.26 Section 3.26 Public Welfare... INSTITUTES OF HEALTH FEDERAL ENCLAVE Traffic Regulations § 3.26 Speed limit. The speed limit is 25 miles per hour, unless otherwise posted. A driver of a vehicle may not exceed the speed limit....

  3. 50 CFR 622.37 - Size limits.

    Science.gov (United States)

    2010-10-01

    ... Register citations affecting § 622.37, see the List of CFR Sections Affected, which appears in the Finding... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Size limits. 622.37 Section 622.37... limits. All size limits in this section are minimum size limits unless specified otherwise. Except...

  4. 49 CFR 218.35 - Yard limits.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Yard limits. 218.35 Section 218.35 Transportation... TRANSPORTATION RAILROAD OPERATING PRACTICES Protection of Trains and Locomotives § 218.35 Yard limits. (a) After August 1, 1977, yard limits must be designated by— (1) Yard limit signs, and (2) Timetable, train...

  5. 50 CFR 20.24 - Daily limit.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Daily limit. 20.24 Section 20.24 Wildlife... (CONTINUED) MIGRATORY BIRD HUNTING Taking § 20.24 Daily limit. No person shall take in any 1 calendar day, more than the daily bag limit or aggregate daily bag limit, whichever applies....

  6. 45 CFR 5.35 - Time limits.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Time limits. 5.35 Section 5.35 Public Welfare... Denial of Records § 5.35 Time limits. (a) General. FOIA sets certain time limits for us to decide whether... time limits, but if it appears that processing your request may take longer than we would wish, we...

  7. 5 CFR 2604.305 - Time limits.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Time limits. 2604.305 Section 2604.305... Disclosure of Records Under FOIA § 2604.305 Time limits. (a)(1) Initial request. Following receipt of a... appeal. (c) Extension of time limits. The time limits specified in either paragraph (a) or (b) of...

  8. 7 CFR 52.3185 - Moisture limits.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Moisture limits. 52.3185 Section 52.3185 Agriculture... Moisture limits. Dried prunes shall not exceed the moisture limits for the applicable grades and kind and size of packaging as designated in Table IV of this subpart except there is no moisture limit when...

  9. 45 CFR 1160.13 - Indemnification limits.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Indemnification limits. 1160.13 Section 1160.13... ACT § 1160.13 Indemnification limits. The dollar amounts of the limits described below are found in the guidelines referred to in § 1160.1 and are based upon the statutory limits in the Arts...

  10. Interfacial dynamics in transport-limited dissolution

    OpenAIRE

    Bazant, Martin Z.

    2006-01-01

    Various model problems of ``transport-limited dissolution'' in two dimensions are analyzed using time-dependent conformal maps. For diffusion-limited dissolution (reverse Laplacian growth), several exact solutions are discussed for the smoothing of corrugated surfaces, including the continuous analogs of ``internal diffusion-limited aggregation'' and ``diffusion-limited erosion''. A class of non-Laplacian, transport-limited dissolution processes are also considered, which raise the general qu...

  11. Limited Deposit Insurance Coverage and Bank Competition

    OpenAIRE

    Shy, Oz; Stenbacka, Rune; Yankov, Vladimir

    2014-01-01

    Deposit insurance designs in many countries place a limit on the coverage of deposits in each bank. However, no limits are placed on the number of accounts held with different banks. Therefore, under limited deposit insurance, some consumers open accounts with different banks to achieve higher or full deposit insurance coverage. We compare three regimes of deposit insurance: No deposit insurance, unlimited deposit insurance, and limited deposit insurance. We show that limited deposit insuranc...

  12. Newtonian limits of warp drive spacetimes

    OpenAIRE

    Natario, Jose

    2004-01-01

    We find a class of warp drive spacetimes possessing Newtonian limits, which we then determine. The same method is used to compute Newtonian limits of the Schwarzschild solution and spatially flat Friedmann-Robertson-Walker cosmological models.

  13. Limits: importance and compliance by measurements

    International Nuclear Information System (INIS)

    Limits in the dose range which is characterized in radiation protection by normal operation must not be considered as a sharp boundary between ''safe'' and ''not safe''. This is because stochastic effects are the underlying issue. Limits are rather a measure to administrate radiation protection standards. Assessing of the quantities subject of limitation, one has the problem that the measured quantities include an inherent uncertainty being often comparable with the quantity itself, where the preset limits have the uncertainty of zero by definition. It will be shown that a uniform consideration of the question of acceptable uncertainty and its relation to the limits is neither necessary nor reasonable. This is because the consideration has to take into account the measured number in relation to the limit, the properties of the assessment technique and the position of the considered quantity in the hierarchy of limits. The rank in the hierarchy is directed whether the quantity is a primary limit or a derived quantity. (orig.)

  14. A MODEL OF MINIMUM SIZE LIMIT REGULATIONS

    OpenAIRE

    Homans, Frances R.; Ruliffson, Jane A.

    1998-01-01

    Minimum size limits have become an increasingly popular management tool in recreational fisheries. This popularity stems from the potential of minimum size limits to accomplish the twin goals of limiting overfishing and improving fishing quality through increasing the average size of fish caught. The success of minimum size limits in achieving these objectives depends in a complicated way on both the behavior of anglers and the biological mechanisms that guide the growth of the fish populatio...

  15. 12 CFR 24.4 - Investment limits.

    Science.gov (United States)

    2010-01-01

    ... ENTITIES, COMMUNITY DEVELOPMENT PROJECTS, AND OTHER PUBLIC WELFARE INVESTMENTS § 24.4 Investment limits. (a... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Investment limits. 24.4 Section 24.4 Banks and...) Limited liability. A national bank may not make an investment under this part that would expose the...

  16. Multiple Limit Cycles in an Immune System

    Institute of Scientific and Technical Information of China (English)

    Xun-cheng Huang; Le-min Zhu; Minaya Villasana

    2008-01-01

    The nonlinear oscillatory phenomenon has been observed in the system of immune response, which corresponds to the limit cycles in the mathematical models. We prove that the system simulating an immune response studied by Huang has at least three limit cycles in the system. The conditions for the multiple limit cycles are useful in analyzing the nonlinear oscillation in immune response.

  17. 12 CFR 616.6600 - Leasing limit.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Leasing limit. 616.6600 Section 616.6600 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM LEASING § 616.6600 Leasing limit. All leases made by Farm Credit System institutions shall be subject to the lending and leasing limit in subpart...

  18. Hopf limit cycles estimation in power systems

    Energy Technology Data Exchange (ETDEWEB)

    Barquin, J.; Gomez, T.; Pagola, L.F. [Univ. Pontificia Comillas, Madrid (Spain). Inst. de Investigacion Tecnologica

    1995-11-01

    This paper addresses the computation of the Hopf limit cycle. This limit cycle is associated to the appearance of an oscillatory instability in dynamical power systems. An algorithm is proposed to estimate the dimensions and shape of this limit cycle. The algorithm is computationally efficient and is able to deal with large power systems. 7 refs, 4 figs, 1 tab

  19. 36 CFR 1004.21 - Speed limits.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Speed limits. 1004.21 Section 1004.21 Parks, Forests, and Public Property PRESIDIO TRUST VEHICLES AND TRAFFIC SAFETY § 1004.21 Speed limits. (a) Speed limits in the area administered by the Presidio Trust are as follows: (1) 15 miles...

  20. 50 CFR 38.13 - Speed limits.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Speed limits. 38.13 Section 38.13 Wildlife... NATIONAL WILDLIFE REFUGE SYSTEM MIDWAY ATOLL NATIONAL WILDLIFE REFUGE Prohibitions § 38.13 Speed limits. No person on Midway Atoll National Wildlife Refuge will exceed the speed limit for automobiles,...

  1. 7 CFR 4274.331 - Loan limits.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Loan limits. 4274.331 Section 4274.331 Agriculture... (IRP) § 4274.331 Loan limits. (a) Intermediary. (1) No loan to an intermediary will exceed the maximum... be used for loans to ultimate recipients that exceed $150,000. This limit does not apply to...

  2. 5 CFR 847.304 - Time limit.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Time limit. 847.304 Section 847.304... Procedures for Elections Under the Retroactive Provisions § 847.304 Time limit. (a) Except as provided in paragraph (b) of this section, the time limit for making an election under subpart D of this part is...

  3. 47 CFR 15.315 - Conducted limits.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Conducted limits. 15.315 Section 15.315... Communications Service Devices § 15.315 Conducted limits. An unlicensed PCS device that is designed to be connected to the public utility (AC) power line must meet the limits specified in § 15.207....

  4. 18 CFR 807.2 - Time limits.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Time limits. 807.2... WITHDRAWAL REGISTRATION § 807.2 Time limits. (a) Except for agricultural water use projects, all registration... limit the responsibility of a project sponsor to apply for and obtain an approval as may be...

  5. 50 CFR 635.20 - Size limits.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Size limits. 635.20 Section 635.20..., DEPARTMENT OF COMMERCE ATLANTIC HIGHLY MIGRATORY SPECIES Management Measures § 635.20 Size limits. Link to an... (160 cm), LJFL. (4) The Atlantic blue and white marlin minimum size limits, specified in paragraphs...

  6. 47 CFR 90.1215 - Power limits.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Power limits. 90.1215 Section 90.1215... § 90.1215 Power limits. The transmitting power of stations operating in the 4940-4990 MHz band must not exceed the maximum limits in this section. (a)(1) The maximum conducted output power should not...

  7. 7 CFR 3560.63 - Loan limits.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Loan limits. 3560.63 Section 3560.63 Agriculture... DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Direct Loan and Grant Origination § 3560.63 Loan limits. (a... housing tax credits, limits will be those specified in § 3560.53(l). (2) Developer's fee. While,...

  8. 50 CFR 20.61 - Importation limits.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Importation limits. 20.61 Section 20.61... PLANTS (CONTINUED) MIGRATORY BIRD HUNTING Importations § 20.61 Importation limits. No person shall import migratory game birds in excess of the following importation limits: (a) Doves and pigeons. (1) From...

  9. 50 CFR 648.145 - Possession limit.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Possession limit. 648.145 Section 648.145... Fishery § 648.145 Possession limit. (a) No person shall possess more than 25 black sea bass, in, or... that is not eligible for a black sea bass moratorium permit are subject to this possession limit....

  10. 32 CFR 806.22 - Time limits.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Time limits. 806.22 Section 806.22 National... INFORMATION ACT PROGRAM § 806.22 Time limits. Any FOIA appeals received after the 60-day time limit are not processed, unless the requester provides adequate justification for failing to comply with the time...

  11. 38 CFR 3.109 - Time limit.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Time limit. 3.109 Section..., Compensation, and Dependency and Indemnity Compensation Administrative § 3.109 Time limit. (a) Notice of time limit for filing evidence. (1) If a claimant's application is incomplete, the claimant will be...

  12. 50 CFR 20.33 - Possession limit.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Possession limit. 20.33 Section 20.33... PLANTS (CONTINUED) MIGRATORY BIRD HUNTING Possession § 20.33 Possession limit. No person shall possess more migratory game birds taken in the United States than the possession limit or the...

  13. 14 CFR 36.805 - Noise limits.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Noise limits. 36.805 Section 36.805...: AIRCRAFT TYPE AND AIRWORTHINESS CERTIFICATION Helicopters § 36.805 Noise limits. (a) Compliance with the... levels of the helicopter are no greater than the applicable limits prescribed under section H36.305...

  14. 47 CFR 15.207 - Conducted limits.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Conducted limits. 15.207 Section 15.207... Conducted limits. (a) Except as shown in paragraphs (b) and (c) of this section, for an intentional radiator... to 30 MHz, shall not exceed the limits in the following table, as measured using a 50 μH/50 ohms...

  15. 47 CFR 25.204 - Power limits.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Power limits. 25.204 Section 25.204... Technical Standards § 25.204 Power limits. (a) In bands shared coequally with terrestrial radio... not exceed the following limits except as provided for in paragraph (c) of this section: +40 dBW...

  16. 7 CFR 1400.106 - Payment limits.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Payment limits. 1400.106 Section 1400.106 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF... SUBSEQUENT CROP, PROGRAM, OR FISCAL YEARS Payment Limitation § 1400.106 Payment limits. (a) Payments made...

  17. 47 CFR 18.307 - Conduction limits.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Conduction limits. 18.307 Section 18.307... Standards § 18.307 Conduction limits. For the following equipment, when designed to be connected to the... on any frequency or frequencies shall not exceed the limits in the following tables. Compliance...

  18. 38 CFR 21.1033 - Time limits.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Time limits. 21.1033... Time limits. The provisions of this section are applicable to informal claims and formal claims. (a) Failure to furnish form, information, or notice of time limit. VA's failure to give a claimant...

  19. 14 CFR 36.501 - Noise limits.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Noise limits. 36.501 Section 36.501..., Commuter Category Airplanes § 36.501 Noise limits. (a) Compliance with this subpart must be shown for— (1... applicable limit set in Part D of appendix F. (c) For aircraft covered by this subpart for...

  20. 14 CFR 36.103 - Noise limits.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Noise limits. 36.103 Section 36.103... Noise limits. (a) For subsonic transport category large airplanes and subsonic jet airplanes compliance... greater than the Stage 3 noise limit prescribed in section B36.5(c) of appendix B of this part. (c)...

  1. 40 CFR 1501.8 - Time limits.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Time limits. 1501.8 Section 1501.8 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY NEPA AND AGENCY PLANNING § 1501.8 Time limits. Although the Council has decided that prescribed universal time limits for the entire NEPA process are...

  2. 50 CFR 648.125 - Possession limit.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Possession limit. 648.125 Section 648.125... § 648.125 Possession limit. (a) No person shall possess more than 10 scup in, or harvested from, the EEZ... moratorium permit are subject to this possession limit. The owner, operator, and crew of a charter or...

  3. 17 CFR 150.2 - Position limits.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Position limits. 150.2 Section 150.2 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION LIMITS ON POSITIONS § 150.2 Position limits. No person may hold or control positions, separately or in combination, net...

  4. 7 CFR 3200.5 - Dollar limitation.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Dollar limitation. 3200.5 Section 3200.5 Agriculture Regulations of the Department of Agriculture (Continued) OFFICE OF PROCUREMENT AND PROPERTY MANAGEMENT... PERSONAL PROPERTY § 3200.5 Dollar limitation. There is no dollar limitation on excess personal...

  5. Flux-limited diffusion with relativistic corrections

    International Nuclear Information System (INIS)

    A recently reported flux-limited diffusion theory is extended to include relativistic terms, correct to first order in the fluid velocity. We show that this diffusion theory is fully flux limited, and yields the correct result for the radiative flux in the classical diffusion limit, namely a Fick's law component plus a v/c convective term

  6. The density limit in JET diverted plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Campbell, D.J.; Clement, S.; Gottardi, N.; Gowers, C.; Harbour, P.; Loarte, A.; Horton, L.; Lingertat, J.; Lowry, C.G.; Saibene, G.; Stamp, M.; Stork, D. [Commission of the European Communities, Abingdon (United Kingdom). JET Joint Undertaking; Monk, R. [Royal Holloway Coll., London (United Kingdom). Dept. of Physics

    1994-07-01

    In JET limiter plasmas the density limit is associated with radiated power fractions of 100% and, in plasmas with carbon limiters, it is invariably disruptive. However, in discharges with solid beryllium limiters the limit is identified with the formation of a MARFE and disruptions are less frequent. In addition, the improved conditioning of the vessel arising from the use of beryllium has significantly improved the density limit scaling, so that the maximum density rises with the square root of the input power. In diverted plasmas several confinement regimes exist, making the characterization of the density limit more complex. While the density limit in L-mode plasmas is generally disruptive, the limit in ELMy and ELM-free H-modes generally prompts a return to the L-mode and a disruption is not inevitable. The density limit does rise with the increasing power, but the L-to-H transition complicates the analysis. Nevertheless, at low plasma currents (<2 MA), densities significantly above the Greenwald limit can be achieved, while at higher currents power handling limitations have constrained the range of density which can be achieved. (authors). 7 refs., 4 figs.

  7. Newtonian limit of axially symmetric spacetimes

    International Nuclear Information System (INIS)

    We illustrate how Ehlers' formal mathematical definition of the Newtonian limit requires additional information to successfully determine the Newtonian limit. This information can be obtained through the physical arguments of Cooperstock's definition. We show that Ehlers' formalism is equivalent to Cooperstock's derivation of the Newtonian limit when the physical arguments are included in the former definition

  8. 49 CFR 663.9 - Audit limitations.

    Science.gov (United States)

    2010-10-01

    ... Audit limitations. (a) An audit under this part is limited to verifying compliance with (1) Applicable... 49 Transportation 7 2010-10-01 2010-10-01 false Audit limitations. 663.9 Section 663.9... audit under this part includes, where appropriate, a copy of a manufacturer's self...

  9. Primordial magnetic field limits from cosmological data

    International Nuclear Information System (INIS)

    We study limits on a primordial magnetic field arising from cosmological data, including that from big bang nucleosynthesis, cosmic microwave background polarization plane Faraday rotation limits, and large-scale structure formation. We show that the physically relevant quantity is the value of the effective magnetic field, and limits on it are independent of how the magnetic field was generated.

  10. Intrinsic and resonance space charge limits

    Energy Technology Data Exchange (ETDEWEB)

    Parzen, G.

    1989-01-01

    The space charge limit in circular proton accelerators has been studied using a simulation program described below. Results from the simulation study indicate a different model for the space charge limit than the often presented models which emphasize resonances due to magnetic field errors. This simulation study suggests that the intrinsic space charge limit plays an important role. The intrinsic space charge limit is the space charge limit, in the absence of magnetic field errors, and is due to the forces generated by the beam itself. In studies of three operating accelerators, which include the AGS, the PS Booster and the Fermilab booster, it was found that the computed intrinsic space charge limit was fairly close to the experimentally observed space charge limit. This result plus studies of the effects of resonances due to magnetic field errors suggest that the intrinsic space charge limit provides an upper bound for the space charge limit which is not far from what is actually achieved by operating accelerators. The resonances present due to magnetic field errors, if strong enough, can prevent the accelerator from achieving the intrinsic space charge limit. However, the effects of these resonances were found to be appreciable only when the beam intensity gets close to the intrinsic space charge limit. Well below the intrinsic space charge limit, there is little beam growth due to magnetic field error driven resonances, and the space charge forces tend to stabilize these resonances. 4 refs., 5 figs.

  11. Intrinsic and resonance space charge limits

    International Nuclear Information System (INIS)

    The space charge limit in circular proton accelerators has been studied using a simulation program described below. Results from the simulation study indicate a different model for the space charge limit than the often presented models which emphasize resonances due to magnetic field errors. This simulation study suggests that the intrinsic space charge limit plays an important role. The intrinsic space charge limit is the space charge limit, in the absence of magnetic field errors, and is due to the forces generated by the beam itself. In studies of three operating accelerators, which include the AGS, the PS Booster and the Fermilab booster, it was found that the computed intrinsic space charge limit was fairly close to the experimentally observed space charge limit. This result plus studies of the effects of resonances due to magnetic field errors suggest that the intrinsic space charge limit provides an upper bound for the space charge limit which is not far from what is actually achieved by operating accelerators. The resonances present due to magnetic field errors, if strong enough, can prevent the accelerator from achieving the intrinsic space charge limit. However, the effects of these resonances were found to be appreciable only when the beam intensity gets close to the intrinsic space charge limit. Well below the intrinsic space charge limit, there is little beam growth due to magnetic field error driven resonances, and the space charge forces tend to stabilize these resonances. 4 refs., 5 figs

  12. Quantum states for Heisenberg limited interferometry

    CERN Document Server

    Uys, H

    2007-01-01

    The phase resolution of interferometers is limited by the so-called Heisenberg limit, which states that the optimum phase sensitivity is inversely proportional to the number of interfering particles $N$, a $1/\\sqrt{N}$ improvement over the standard quantum limit. We have used simulated annealing, a global optimization strategy, to systematically search for quantum interferometer input states that approach the Heisenberg limited uncertainty in estimates of the interferometer phase shift. We compare the performance of these states to that of other non-classical states already known to yield Heisenberg limited uncertainty.

  13. Quantum states for Heisenberg limited interferometry

    Science.gov (United States)

    Uys, Hermann; Meystre, Pierre

    2007-06-01

    An important aspect of quantum metrology is the engineering of quantum states with which to achieve Heisenberg limited measurement precision. In this limit the measurement uncertainty is inversely proportional to the number of interfering particles, N, a 1/√N improvement over the standad quantum limit. We have used numerical global optimization strategies to systematically search for quantum interferometer input states that achieve Heisenberg limited uncertainty in estimates of the interferometer phase shift. We compare the performance of candidates so obtained with that of non-classical states already known to yield Heisenberg limited uncertainty.

  14. Quantum states for Heisenberg-limited interferometry

    Science.gov (United States)

    Uys, H.; Meystre, P.

    2007-07-01

    The phase sensitivity of interferometers is limited by the so-called Heisenberg limit, which states that the optimum phase sensitivity is inversely proportional to the number of interfering particles N , a 1/N improvement over the standard quantum limit. We have used simulated annealing, a global optimization strategy, to systematically search for quantum interferometer input states that approach the Heisenberg-limited uncertainty in estimates of the interferometer phase shift. We compare the performance of these states to that of other nonclassical states already known to yield Heisenberg-limited uncertainty.

  15. Quantum states for Heisenberg-limited interferometry

    International Nuclear Information System (INIS)

    The phase sensitivity of interferometers is limited by the so-called Heisenberg limit, which states that the optimum phase sensitivity is inversely proportional to the number of interfering particles N, a 1/√(N) improvement over the standard quantum limit. We have used simulated annealing, a global optimization strategy, to systematically search for quantum interferometer input states that approach the Heisenberg-limited uncertainty in estimates of the interferometer phase shift. We compare the performance of these states to that of other nonclassical states already known to yield Heisenberg-limited uncertainty

  16. Plane wave limits and T-duality

    International Nuclear Information System (INIS)

    The Penrose limit is generalized to show that, any leading order solution of the low-energy field equations in any one of the five string theories has a plane wave solution as a limit. This limiting procedure takes into account all the massless fields that may arise and commutes with the T-duality so that any dual solution has again a plane wave limit. The scaling rules used in the limit are unique and stem from the scaling property of the D = 11 supergravity action. Although the leading order dual solutions need not be exact or supersymmetric, their plane wave limits always preserve some portion of the Poincare supersymmetry and solve the relevant field equations in all powers of the string tension parameter. Further properties of the limiting procedure are discussed. (author)

  17. Penrose limits, supergravity and brane dynamics

    International Nuclear Information System (INIS)

    We investigate the Penrose limits of classical string and M-theory backgrounds. We prove that the number of (super)symmetries of a supergravity background never decreases in the limit. We classify all the possible Penrose limits of AdSxS spacetimes and of supergravity brane solutions. We also present the Penrose limits of various other solutions: intersecting branes, supersymmetric black holes and strings in diverse dimensions, and cosmological models. We explore the Penrose limit of an isometrically embedded spacetime and find a generalization to spaces with more than one time. Finally, we show that the Penrose limit is a large tension limit for all branes including those with fields of Born-Infeld type

  18. A generalized VMD mechanism for radiative decays of c anti c mesons

    International Nuclear Information System (INIS)

    A generalized VMD mechanism, implemented through the QCP model, is proposed for E1 and M1 decays of cantic mesons wherein the photon couples to two infinite sequences of radial excitations of 3S1 and 3D1 cantic states. The results reveal good accord with data under the conventional assignments, with a parameter signifying a reduced magnetic coupling of psi-ions with c quarks

  19. Existence of Multiagent Equilibria with Limited Agents

    CERN Document Server

    Bowling, M; 10.1613/jair.1332

    2011-01-01

    Multiagent learning is a necessary yet challenging problem as multiagent systems become more prevalent and environments become more dynamic. Much of the groundbreaking work in this area draws on notable results from game theory, in particular, the concept of Nash equilibria. Learners that directly learn an equilibrium obviously rely on their existence. Learners that instead seek to play optimally with respect to the other players also depend upon equilibria since equilibria are fixed points for learning. From another perspective, agents with limitations are real and common. These may be undesired physical limitations as well as self-imposed rational limitations, such as abstraction and approximation techniques, used to make learning tractable. This article explores the interactions of these two important concepts: equilibria and limitations in learning. We introduce the question of whether equilibria continue to exist when agents have limitations. We look at the general effects limitations can have on agent b...

  20. The Translation of Numerals and its Limits

    Institute of Scientific and Technical Information of China (English)

    吴贤雯

    2013-01-01

    Through probing into the diversity of numerals’functions in language use which gives prominence to the importance of numeral translation, this paper aims to analyze the limits of numeral translation and explain the cause for these limits. The analy-sis of the limits in numeral translation is guided by the principle of functional equivalence. It is discussed that in numeral transla-tion, the limits on different levels of culture, image, sound and form arise when the full functional equivalence can not be achieved. Furthermore, this paper finds that the differences in culture and formal structure as well as the semantic fuzziness are three reasons for the presence of limits in numeral translation. However, the author suggests that these limits in numeral transla-tion can be adjusted with the further development of research on translation methodology and the deep infiltration of different cultures.

  1. Investigation of pulsed voltage limiters characteristics

    Directory of Open Access Journals (Sweden)

    Karimov A. V.

    2012-06-01

    Full Text Available A new method for measuring the voltage limit is offered. It has been designed to measure high-power pulsed current of voltage limiters. The error of this method is half as much as the error of the known method of direct measurement. The investigation of dependence of power capability of single-crystal and double-crystal voltage limiters and of the pulsed operation time on pulse duration.

  2. Investigation of pulsed voltage limiters characteristics

    OpenAIRE

    Karimov A. V.; Yodgorova D. M.; Rakhmatov A. Z.; Skornyakov S. L.; Petrov D. A.; Abdulkhayev O. A.

    2012-01-01

    A new method for measuring the voltage limit is offered. It has been designed to measure high-power pulsed current of voltage limiters. The error of this method is half as much as the error of the known method of direct measurement. The investigation of dependence of power capability of single-crystal and double-crystal voltage limiters and of the pulsed operation time on pulse duration.

  3. 19 CFR 145.23 - Time limits.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Time limits. 145.23 Section 145.23 Customs Duties... (CONTINUED) MAIL IMPORTATIONS Administrative Review of Mail Entries § 145.23 Time limits. A mail entry may be... requests such amendment within the time limits prescribed therein (see §§ 173.4 and 173.5 of this...

  4. Pauli-Limited Superconductivity in Small Grains

    OpenAIRE

    Bonsager, M. C.; MacDonald, A. H.

    1998-01-01

    We report on an exploration of the mean-field phase diagram for Pauli-limited superconductivity in small metallic grains. Emphasis is placed on the crossover from the ultra-small grain limit where superconductivity disappears to the bulk thin-film limit as the single-particle level spacing in the grain decreases. We find that the maximum Zeeman coupling strength compatible with superconductivity increases with decreasing grain size, in spite of a monotonically decreasing condensation energy p...

  5. Limit Cycle Oscillations in Pacemaker Cells

    CERN Document Server

    Endresen, L P; Endresen, Lars Petter; Skarland, Nils

    1999-01-01

    In recent decades, several mathematical models describing the pacemaker activity of the rabbit sinoatrial node have been developed. We demonstrate that it is not possible to establish the existence, uniqueness, and stability of a limit cycle oscillation in those models. Instead we observe an infinite number of limit cycles. We then display numerical results from a new model, with a limit cycle that can be reached from many different initial conditions.

  6. Back to Classics: Teaching Limits Through Infinitesimals

    OpenAIRE

    Todorov, Todor D.

    2011-01-01

    The usual $\\epsilon,\\delta$-definition of the limit of a function (whether presented at a rigorous or an intuitive level) requires a "candidate $L$" for the limit value. Thus, we have to start our first calculus course with "guessing" instead of "calculating". In this paper we criticize the method of using calculators for the purpose of selecting candidates for $L$. We suggest an alternative: a working formula for calculating the limit value L of a real function in terms of infinitesimals. Ou...

  7. Nuclear Physics Around the Unitarity Limit

    CERN Document Server

    König, Sebastian; Hammer, H -W; van Kolck, U

    2016-01-01

    We argue that many features of the structure of nuclei can be understood in the unitarity limit, where the two-nucleon S-waves have bound states at zero energy. In this limit, the only dimensionful parameter, related to the breaking of scale invariance to a discrete scaling symmetry, is set by the triton binding energy. For A <= 4 nucleons, we demonstrate that the spectrum can be obtained as a controlled perturbative expansion around the unitarity limit.

  8. Classical limits of an extended unitary model

    International Nuclear Information System (INIS)

    The paper studies the limiting cases of an extended unitary model and it is shown that rotational, vibrational and transition excitation spectra are generated depending on the parameters ratio. The limits concerned resemble, by some properties, the analogous limits of an interacting boson model, however, the physical nature of the two models is different. Their generality is caused by the group structure similarity. 31 refs.; 5 figs.; 6 tabs

  9. Time limiting of access to the Internet

    OpenAIRE

    Medvešček, Edi

    2013-01-01

    The thesis deals with time limiting of access to the Internet. In the first part of the thesis we present and analyse already existing solutions of such restricted Internet usage, whereas in the second part, our own application for time limiting is developed. We built into the application various functionalities, allowing the user a number of possibilities for limiting the access to the Internet. We mainly focused on security and reliability, with special attention paid to the potential avoid...

  10. SHORT CIRCUIT CURRENT LIMITER IN AC NETWORK

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Short circuit is a serious fault in power network.Some novelcircuit topologies of current limiter using power electronic technology have been developed,which can limit the fault current to any desired level without much penalty.The operating principle and control strategies of such current limiters are discussed in detail.Simulation and experimental results are given to verify the performance of the current limiter,which can meet the requirements set for locations of bus tie,feeder,as well as the main transformer in the distribution network.

  11. Implementing Risk-Limiting Audits in California

    OpenAIRE

    Hall, Joseph L.; Miratrix, Luke W.; Stark, Philip B.; Briones, Melvin; Ginnold, Elaine; Oakley, Freddie; Peaden, Martin; Pellerin, Gail; Stanionis, Tom; Webber, Tricia

    2009-01-01

    Risk-limiting post-election audits limit the chance of certifying an electoral outcome if the outcome is not what a full hand count would show. Building on previous work, we report on pilot risk-limiting audits in four elections during 2008 in three California counties: one during the February 2008 Primary Election in Marin County and three during the November 2008 General Elections in Marin, Santa Cruz and Yolo Counties. We explain what makes an audit risk-limiting and how existing and pro...

  12. Impact limiter retention using a tape joint

    International Nuclear Information System (INIS)

    Sandia National Laboratories has developed the Beneficial Uses Shipping System (BUSS) cask for the transportation of up to a megacurie of radiation source capsules. This work was done under contract to the Department of Energy. The BUSS cask employs polyurethane foam impact limiters that fit onto the ends of the cask. A foam impact limiter takes energy out of the system during a hypothetical accident condition by allowing foam crush and large deformations to occur. This, in turn, precludes high stresses or deformations from occurring in the cask. Depending on the nature of the impact limiters and large deformations experienced, retaining the limiters on a cask during a 9 meter regulatory drop poses a design challenge. Impact limiter retention becomes a concern to ensure the cask does not experience higher decelerations during secondary impacts without impact limiters in place. During the 9 meter drop, the impact limiters absorb the energy required to confine the cask deceleration to acceptable levels. However, if the impact limiters were removed from the cask due to initial impact, higher cask stress levels could occur during any secondary or rebound effects. A tape joint has been designed to solve the problem of retaining impact limiters onto the BUSS cask during impact loadings

  13. Inproved grade length limitation of freeways

    Institute of Scientific and Technical Information of China (English)

    XING En-hui; PEI Yu-long

    2006-01-01

    A method of ascertaining grade length limitation of freeways in mountain terrain is presented. The relationship models between 15th percentile speeds and grades were built through the surveys and analyses of operation speeds on 7 typical sections of 3 freeways in mountain terrain. Using 15th percentile and 85th percentile as speed limitations, the methods of determining admitted velocities were put forward according to the grades. Deceleration distances of longitudinal slopeways were analyzed utilizing the theories of vehicle. According to the results of analysis, grade length limitation was loosed. Finally the values of grade length limitation for freeways were put forward. The results could be used as references for freeway design.

  14. Biological measurement beyond the quantum limit

    CERN Document Server

    Taylor, Michael A; Daria, Vincent; Knittel, Joachi; Hage, Boris; Bachor, Hans-A; Bowen, Warwick P

    2012-01-01

    Quantum noise places a fundamental limit on the per photon sensitivity attainable in optical measurements. This limit is of particular importance in biological measurements, where the optical power must be constrained to avoid damage to the specimen. By using non-classically correlated light, we demonstrated that the quantum limit can be surpassed in biological measurements. Quantum enhanced microrheology was performed within yeast cells by tracking naturally occurring lipid granules with sensitivity 2.4 dB beyond the quantum noise limit. The viscoelastic properties of the cytoplasm could thereby be determined with a 64% improved measurement rate. This demonstration paves the way to apply quantum resources broadly in a biological context.

  15. TFTR movable limiter instrumentation and controls

    International Nuclear Information System (INIS)

    The TFTR movable limiter is a single poloidal limiter located within one 18 /SUP o/ segment of the vacuum vessel. It consists of three (3) interconnected inconel backing plates covered with titanium carbide coated graphite tiles. The backing plates are positioned by three independent screw drive actuators. Cooling water is fed through the horizontal port cover to tubes brazed onto the backs of the backing plates. Thermocouples monitor the limiter temperature. (1) and more fully described in refs. (1) and (2). The positioning actuators are driven by independently controlled DC servo motors, controlled either locally or from CICADA. Drive motor shaft position is monitored by chain driven encoders and potentiometers. Limiter blade position can be varied to suit any plasma within the operating range. CICADA is programmed to keep the limiter stroke within safe operating limits. A microprocessor duplicates the CICADA protective function allowing limiter operation without CICADA. The potentiometer signal is sent to an analog computer, which safeguards the limiter against failure of the encoders or the micro-processor. Cooling water flows through the limiter in 3 separate paths, one for each blade. The flow rate and temperature rise through each loop are measured accurately to allow CICADA to calculate the heat into each blade. The water system is also interlocked and alarmed to prevent dumping of water into the vacuum vessel

  16. 46 CFR 520.7 - Tariff limitations.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false Tariff limitations. 520.7 Section 520.7 Shipping FEDERAL MARITIME COMMISSION REGULATIONS AFFECTING OCEAN SHIPPING IN FOREIGN COMMERCE CARRIER AUTOMATED TARIFFS § 520.7 Tariff limitations. (a) General. Tariffs published pursuant to this part shall: (1) Be clear...

  17. Tokamak advanced pump limiter experiments and analysis

    International Nuclear Information System (INIS)

    Experiments with pump limiter modules on several operating tokamaks establish such limiters as efficient collectors of particles and has demonstrated the importance of ballistic scattering as predicted theoretically. Plasma interaction with recycling neutral gas appears to become important as the plasma density increases and the effective ionization mean free path within the module decreases. In limiters with particle collection but without active internal pumping, the neutral gas pressure is found to vary nonlinearly with the edge plasma density at the highest densities studies. Both experiments and theory indicate that the energy spectrum of gas atoms in the pump ducting is non-thermal, consistent with the results of Monte Carlo neutral atom transport calculations. The distribution of plasma power over the front surface of such modules has been measured and appears to be consistent with the predictions of simple theory. Initial results from the latest experiment on the ISX-B tokamak with an actively pumped limiter module demonstrates that the core plasma density can be controlled with a pump limiter and that the scrape-off layer plasma can partially screen the core plasma from gas injection. The results from module pump limiter experiments and from the theory and design analysis of advanced pump limiters for reactors are used to suggest the major features of a definitive, axisymmetric, toroidal belt pump limiter experiment

  18. Performance Limitation of Subband Adaptive Equalisers

    OpenAIRE

    Mohamod, H.; Weiss, S.; Rupp, M.; Hanzo, L.

    2006-01-01

    The aim of this reported work was identifying and quantifying limitation for the subband adaptive equalisers. The derived Wiener solution is compared against simulations for the subband equaliser, and it is verified that aliasing caused in the subband decimation can be considered equivalent to channel noise. Finally, how this limitation can be mitigated by careful system design is discussed.

  19. 47 CFR 95.1019 - Marketing limitations.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Marketing limitations. 95.1019 Section 95.1019 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PERSONAL RADIO SERVICES Low Power Radio Service (LPRS) General Provisions § 95.1019 Marketing limitations....

  20. 47 CFR 95.1219 - Marketing limitations.

    Science.gov (United States)

    2010-10-01

    ... SERVICES Medical Device Radiocommunication Service (MedRadio) § 95.1219 Marketing limitations. Transmitters intended for operation in the MedRadio Service may be marketed and sold only for the permissible... 47 Telecommunication 5 2010-10-01 2010-10-01 false Marketing limitations. 95.1219 Section...

  1. Superlenses to overcome the diffraction limit.

    Science.gov (United States)

    Zhang, Xiang; Liu, Zhaowei

    2008-06-01

    The imaging resolution of conventional lenses is limited by diffraction. Artificially engineered metamaterials now offer the possibility of building a superlens that overcomes this limit. We review the physics of such superlenses and the theoretical and experimental progress in this rapidly developing field. Superlenses have great potential in applications such as biomedical imaging, optical lithography and data storage. PMID:18497850

  2. 5 CFR 185.147 - Limitations.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Limitations. 185.147 Section 185.147 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROGRAM FRAUD CIVIL REMEDIES § 185.147 Limitations. (a) The notice of hearing with respect to a claim or statement must be served...

  3. 33 CFR 401.28 - Speed limits.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Speed limits. 401.28 Section 401... TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Seaway Navigation § 401.28 Speed limits. (a) The maximum speed over the bottom for a vessel of more than 12 m in overall length shall be regulated so as not...

  4. 32 CFR 935.132 - Speed limits.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Speed limits. 935.132 Section 935.132 National... WAKE ISLAND CODE Motor Vehicle Code § 935.132 Speed limits. Each person operating a motor vehicle on Wake Island shall operate it at a speed— (a) That is reasonable, safe, and proper, considering time...

  5. 38 CFR 36.4214 - Geographical limits.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Geographical limits. 36.4214 Section 36.4214 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED... Preparation General Provisions § 36.4214 Geographical limits. The site for any manufactured home...

  6. 14 CFR 27.25 - Weight limits.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Weight limits. 27.25 Section 27.25 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: NORMAL CATEGORY ROTORCRAFT Flight General § 27.25 Weight limits. (a) Maximum weight. The...

  7. 7 CFR 3560.612 - Loan limits.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Loan limits. 3560.612 Section 3560.612 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS On-Farm Labor Housing § 3560.612 Loan limits. The...

  8. 40 CFR 1502.7 - Page limits.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Page limits. 1502.7 Section 1502.7 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY ENVIRONMENTAL IMPACT STATEMENT § 1502.7 Page limits. The text of final environmental impact statements (e.g., paragraphs (d) through (g) of §...

  9. 27 CFR 8.4 - Jurisdictional limits.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Jurisdictional limits. 8.4 Section 8.4 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS EXCLUSIVE OUTLETS Scope of Regulations § 8.4 Jurisdictional limits. (a)...

  10. 24 CFR 585.202 - Award limits.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Award limits. 585.202 Section 585.202 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... DEVELOPMENT COMMUNITY FACILITIES YOUTHBUILD PROGRAM Youthbuild Planning Grants § 585.202 Award limits....

  11. 25 CFR 87.3 - Time limits.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Time limits. 87.3 Section 87.3 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR TRIBAL GOVERNMENT USE OR DISTRIBUTION OF INDIAN JUDGMENT FUNDS § 87.3 Time limits. (a) The Secretary shall cause to begin as early as possible the necessary research...

  12. 47 CFR 73.855 - Ownership limits.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Ownership limits. 73.855 Section 73.855 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES RADIO BROADCAST SERVICES Low Power FM Broadcast Stations (LPFM) § 73.855 Ownership limits. (a) No authorization for an...

  13. 40 CFR 503.13 - Pollutant limits.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Pollutant limits. 503.13 Section 503.13 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SEWAGE SLUDGE STANDARDS FOR THE USE OR DISPOSAL OF SEWAGE SLUDGE Land Application § 503.13 Pollutant limits. (a) Sewage sludge....

  14. 47 CFR 15.107 - Conducted limits.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Conducted limits. 15.107 Section 15.107... Conducted limits. (a) Except for Class A digital devices, for equipment that is designed to be connected to... power line on any frequency or frequencies within the band 150 kHz to 30 MHz shall not exceed the...

  15. 38 CFR 36.4332 - Geographical limits.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Geographical limits. 36.4332 Section 36.4332 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED... Geographical limits. Any real property purchased, constructed, altered, improved, or repaired with the...

  16. 27 CFR 10.4 - Jurisdictional limits.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Jurisdictional limits. 10.4 Section 10.4 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS COMMERCIAL BRIBERY Scope of Regulations § 10.4 Jurisdictional limits....

  17. 49 CFR 10.43 - Time limits.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Time limits. 10.43 Section 10.43 Transportation Office of the Secretary of Transportation MAINTENANCE OF AND ACCESS TO RECORDS PERTAINING TO INDIVIDUALS Correction of Records § 10.43 Time limits. Within ten days (excluding Saturday, Sunday, and legal...

  18. 38 CFR 36.4523 - Geographical limits.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Geographical limits. 36.4523 Section 36.4523 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) LOAN GUARANTY Direct Loans § 36.4523 Geographical limits. Any real property purchased, constructed,...

  19. 47 CFR 10.430 - Character limit.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Character limit. 10.430 Section 10.430 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMERCIAL MOBILE ALERT SYSTEM Alert Message Requirements § 10.430 Character limit. A CMAS Alert Message processed by a Participating CMS Provider must...

  20. 14 CFR 31.14 - Weight limits.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Weight limits. 31.14 Section 31.14 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: MANNED FREE BALLOONS Flight Requirements § 31.14 Weight limits. (a) The range of weights...

  1. 27 CFR 6.4 - Jurisdictional limits.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Jurisdictional limits. 6.4 Section 6.4 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS âTIED-HOUSEâ Scope of Regulations § 6.4 Jurisdictional limits. (a) General....

  2. 32 CFR 169a.19 - Study limits.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Study limits. 169a.19 Section 169a.19 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DEFENSE CONTRACTING COMMERCIAL ACTIVITIES PROGRAM PROCEDURES Procedures § 169a.19 Study limits. No DoD funds shall be available to perform any...

  3. 10 CFR 14.27 - Time limit.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Time limit. 14.27 Section 14.27 Energy NUCLEAR REGULATORY COMMISSION ADMINISTRATIVE CLAIMS UNDER FEDERAL TORT CLAIMS ACT Filing Procedures and Requirements § 14.27 Time limit. The claimant shall furnish evidence and information of the types described in 10 CFR...

  4. 19 CFR 357.106 - Time limits.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Time limits. 357.106 Section 357.106 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT OF COMMERCE SHORT SUPPLY PROCEDURES § 357.106 Time limits. (a) The Secretary will determine, no later than the day specified in paragraph (b) of...

  5. 27 CFR 11.4 - Jurisdictional limits.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Jurisdictional limits. 11.4 Section 11.4 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS CONSIGNMENT SALES Scope of Regulations § 11.4 Jurisdictional limits....

  6. 38 CFR 36.4411 - Geographical limits.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Geographical limits. 36.4411 Section 36.4411 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED... Geographical limits. Any real property purchased, constructed, altered, improved, repaired, or...

  7. 14 CFR 29.25 - Weight limits.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Weight limits. 29.25 Section 29.25 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Flight General § 29.25 Weight limits. (a) Maximum weight....

  8. 5 CFR 1205.23 - Time limits.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Time limits. 1205.23 Section 1205.23 Administrative Personnel MERIT SYSTEMS PROTECTION BOARD ORGANIZATION AND PROCEDURES PRIVACY ACT REGULATIONS Amendment of Records § 1205.23 Time limits. The Clerk of the Board, Regional Director, or...

  9. 10 CFR 52.9 - Jurisdictional limits.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Jurisdictional limits. 52.9 Section 52.9 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS General Provisions § 52.9 Jurisdictional limits. No permit, license, standard design approval, or standard...

  10. 12 CFR 1805.402 - Assistance limits.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Assistance limits. 1805.402 Section 1805.402 Banks and Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS PROGRAM Investment Instruments § 1805.402 Assistance limits....

  11. 14 CFR 25.25 - Weight limits.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Weight limits. 25.25 Section 25.25 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Flight General § 25.25 Weight limits. (a) Maximum weights....

  12. Bargaining with Many Players: A Limit Result

    OpenAIRE

    Klaus Kultti; Hannu Vartiainen

    2008-01-01

    We provide a simple characterization of the stationary subgame perfect equilibrium of an alternating offers bargaining game when the number of players increases without a limit. Core convergence literature is emulated by increasing the number of players by replication. The limit allocation is interpreted in terms of Walrasian market for being the first proposer.

  13. The Newtonian limit at intermediate energies

    International Nuclear Information System (INIS)

    We study the metric solutions for the gravitational equations in Modified Gravity Models (MGMs). In models with negative powers of the scalar curvature, we show that the Newtonian Limit (NL) is well defined as a limit at intermediate energies, in contrast with the usual low energy interpretation. Indeed, we show that the gravitational interaction is modified at low densities or low curvatures

  14. The Newtonian limit at intermediate energies

    OpenAIRE

    Cembranos, J. A. R.

    2005-01-01

    We study the metric solutions for the gravitational equations in Modified Gravity Models (MGMs). In models with negative powers of the scalar curvature, we show that the Newtonian Limit (NL) is well defined as a limit at intermediate energies, in contrast with the usual low energy interpretation. Indeed, we show that the gravitational interaction is modified at low densities or low curvatures.

  15. Central Limit Theorem for Coloured Hard Dimers

    Directory of Open Access Journals (Sweden)

    Maria Simonetta Bernabei

    2010-01-01

    Full Text Available We study the central limit theorem for a class of coloured graphs. This means that we investigate the limit behavior of certain random variables whose values are combinatorial parameters associated to these graphs. The techniques used at arriving this result comprise combinatorics, generating functions, and conditional expectations.

  16. 31 CFR 281.7 - Limitations.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Limitations. 281.7 Section 281.7 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FOREIGN EXCHANGE OPERATIONS § 281.7 Limitations....

  17. 50 CFR 640.21 - Harvest limitations.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Harvest limitations. 640.21 Section 640.21... § 640.21 Harvest limitations. (a) Berried lobsters. A berried (egg-bearing) spiny lobster or slipper... immediately to the water unharmed. (2) No person may harvest or attempt to harvest a spiny lobster by...

  18. 47 CFR 24.133 - Emission limits.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Emission limits. 24.133 Section 24.133... SERVICES Narrowband PCS § 24.133 Emission limits. (a) The power of any emission shall be attenuated below... the lesser attenuation. (b) The measurements of emission power can be expressed in peak or...

  19. 47 CFR 90.1323 - Emission limits.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Emission limits. 90.1323 Section 90.1323... MOBILE RADIO SERVICES Wireless Broadband Services in the 3650-3700 MHz Band § 90.1323 Emission limits. (a) The power of any emission outside a licensee's frequency band(s) of operation shall be...

  20. 47 CFR 27.53 - Emission limits.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Emission limits. 27.53 Section 27.53... COMMUNICATIONS SERVICES Technical Standards § 27.53 Emission limits. (a) For operations in the 2305-2320 MHz band and the 2345-2360 MHz band, the power of any emission outside a licensee's frequency band(s)...

  1. 40 CFR 63.802 - Emission limits.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 10 2010-07-01 2010-07-01 false Emission limits. 63.802 Section 63.802... EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Wood Furniture Manufacturing Operations § 63.802 Emission limits. (a) Each owner or...

  2. 40 CFR 61.162 - Emission limits.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Emission limits. 61.162 Section 61.162... EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standard for Inorganic Arsenic Emissions From Glass Manufacturing Plants § 61.162 Emission limits. (a) The owner or operator of an...

  3. 47 CFR 90.669 - Emission limits.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Emission limits. 90.669 Section 90.669... 896-901/935-940 Mhz Band § 90.669 Emission limits. (a) On any frequency in an MTA licensee's spectrum block that is adjacent to a non-MTA frequency, the power of any emission shall be attenuated below...

  4. 46 CFR 45.185 - Tow limitations.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Tow limitations. 45.185 Section 45.185 Shipping COAST... Barges on Lake Michigan Routes § 45.185 Tow limitations. (a) Barges must not be manned. (b) No more than three barges per tow on the Milwaukee, St. Joseph, and Muskegon routes. (c) Barges must not be more...

  5. Visualizing the Central Limit Theorem through Simulation

    Science.gov (United States)

    Ruggieri, Eric

    2016-01-01

    The Central Limit Theorem is one of the most important concepts taught in an introductory statistics course, however, it may be the least understood by students. Sure, students can plug numbers into a formula and solve problems, but conceptually, do they really understand what the Central Limit Theorem is saying? This paper describes a simulation…

  6. 26 CFR 1.856-2 - Limitations.

    Science.gov (United States)

    2010-04-01

    ... gain from the sale or other disposition of real property for the 30-percent-of-gross-income limitation... or taxes, does not constitute the acquisition of “other property” for purposes of this subparagraph... TAXES Real Estate Investment Trusts § 1.856-2 Limitations. (a) Effective date. The provisions of part...

  7. Anomalies and the Large N Limit

    International Nuclear Information System (INIS)

    Operator algebra aspects of the Large N limit of Bosonic vector models are analyzed. It is shown that the Large N limit is a classical theory, and a general method, based on defromation quatization, for calculating the Poisson algebra of dynamical observables in the limiting classical theory is presented. The Poisson algebra of O(N) invariant observables of Bosonic vector models is constructed in this approach, and is shown to be a central extension of the Symplectic Lie algebra. The relation of the central term to anomalies is discussed. A comparision of the classical theories obtained in the Large N limit and that in the small (ℎ/2π) limit is also presented

  8. Reflective Optical Limiter Based on Resonant Transmission

    CERN Document Server

    Makri, Eleana; Vitebskiy, Ilya

    2014-01-01

    Optical limiters transmit low-level radiation while blocking electromagnetic pulses with excessively high energy (energy limiters) or with excessively high peak intensity (power limiters). A typical optical limiter absorbs most of the high-level radiation which can cause its destruction via overheating. Here we introduce the novel concept of a reflective energy limiter which blocks electromagnetic pulses with excessively high total energy by reflecting them back to space, rather than absorbing them. The idea is to use a defect layer with temperature dependent loss tangent embedded in a low-loss photonic structure. The low energy pulses with central frequency close to that of the localized defect mode will pass through. But if the cumulative energy carried by the pulse exceeds certain level, the entire photonic structure reflects the incident light (and does not absorb it!) for a broad frequency window. The underlying physical mechanism is based on self-regulated impedance mismatch which increases dramatically...

  9. Self-triggering superconducting fault current limiter

    Energy Technology Data Exchange (ETDEWEB)

    Yuan, Xing (Albany, NY); Tekletsadik, Kasegn (Rexford, NY)

    2008-10-21

    A modular and scaleable Matrix Fault Current Limiter (MFCL) that functions as a "variable impedance" device in an electric power network, using components made of superconducting and non-superconducting electrically conductive materials. The matrix fault current limiter comprises a fault current limiter module that includes a superconductor which is electrically coupled in parallel with a trigger coil, wherein the trigger coil is magnetically coupled to the superconductor. The current surge doing a fault within the electrical power network will cause the superconductor to transition to its resistive state and also generate a uniform magnetic field in the trigger coil and simultaneously limit the voltage developed across the superconductor. This results in fast and uniform quenching of the superconductors, significantly reduces the burnout risk associated with non-uniformity often existing within the volume of superconductor materials. The fault current limiter modules may be electrically coupled together to form various "n" (rows).times."m" (columns) matrix configurations.

  10. Reverse engineering of inductive fault current limiters

    Energy Technology Data Exchange (ETDEWEB)

    Pina, J M; Neves, M Ventim; Rodrigues, A L [Centre of Technology and Systems Faculdade de Ciencias e Tecnologia, Nova University of Lisbon Monte de Caparica, 2829-516 Caparica (Portugal); Suarez, P; Alvarez, A, E-mail: jmmp@fct.unl.p [' Benito Mahedero' Group of Electrical Applications of Superconductors Escuela de IngenierIas Industrials, University of Extremadura Avenida de Elvas s/n, 06006 Badajoz (Spain)

    2010-06-01

    The inductive fault current limiter is less compact and harder to scale to high voltage networks than the resistive one. Nevertheless, its simple construction and mechanical robustness make it attractive in low voltage grids. Thus, it might be an enabling technology for the advent of microgrids, low voltage networks with dispersed generation, controllable loads and energy storage. A new methodology for reverse engineering of inductive fault current limiters based on the independent analysis of iron cores and HTS cylinders is presented in this paper. Their electromagnetic characteristics are used to predict the devices' hysteresis loops and consequently their dynamic behavior. Previous models based on the separate analysis of the limiters' components were already derived, e.g. in transformer like equivalent models. Nevertheless, the assumptions usually made may limit these models' application, as shown in the paper. The proposed methodology obviates these limitations. Results are validated through simulations.

  11. Pumped limiter results on TFR Tokamak plasma

    International Nuclear Information System (INIS)

    Pump limiter experiments are carried out in the TFR Tokamak. The pump limiter is located in the outer part of the torus, its double- throat head is made of graphite tiles and it is pumped by a 2000 ls-1 titanium sublimation pump. The first attempts showed that the exhaust efficiency of this pump limiter was low (ε = 1.5% of the total plasma particle efflux). To improve these results, a new limiter head with a single longer throat has been built; particles were better trapped and the pumping provided an important decrease of the recycling coefficient. Geometric features mainly explain the increase by a factor 3.5 of the exhaust efficiency (ε = 5.5%). Ion temperature of the order of a few eV has been deduced from Doppler broadening measurements at the neutralizer plate of the pump limiter

  12. Functional Limitations and Gender Differences: Neighborhood Effects.

    Science.gov (United States)

    Wilson-Genderson, Maureen; Pruchno, Rachel

    2015-07-01

    Rates of functional limitations are consistently higher for women than for men, but it is not clear why. While some studies have examined individual risk factors, others have turned to broader social characteristics. We examined the effects of both individual and neighborhood characteristics associated with the functional limitations of older men and women. Multilevel structural equation models were developed using data from a random digit dial sample of 5,688 adults aged 50 to 74 years living in New Jersey. We found that greater numbers of fast-food restaurants, storefronts, and supermarkets was associated with more functional limitations of women, while greater numbers of fast-food restaurants was the only neighborhood characteristic associated with more functional limitations of men. Functional limitations of women, but not men, are affected by multiple neighborhood characteristics. This research reveals that specific neighborhood contextual characteristics, not just poverty, are associated with the health of community-dwelling adults. PMID:26543060

  13. The limits on trypanosomatid morphological diversity.

    Directory of Open Access Journals (Sweden)

    Richard John Wheeler

    Full Text Available Cell shape is one, often overlooked, way in which protozoan parasites have adapted to a variety of host and vector environments and directional transmissions between these environments. Consequently, different parasite life cycle stages have characteristic morphologies. Trypanosomatid parasites are an excellent example of this in which large morphological variations between species and life cycle stage occur, despite sharing well-conserved cytoskeletal and membranous structures. Here, using previously published reports in the literature of the morphology of 248 isolates of trypanosomatid species from different hosts, we perform a meta-analysis of the occurrence and limits on morphological diversity of different classes of trypanosomatid morphology (trypomastigote, promastigote, etc. in the vertebrate bloodstream and invertebrate gut environments. We identified several limits on cell body length, cell body width and flagellum length diversity which can be interpreted as biomechanical limits on the capacity of the cell to attain particular dimensions. These limits differed for morphologies with and without a laterally attached flagellum which we suggest represent two morphological superclasses, the 'juxtaform' and 'liberform' superclasses. Further limits were identified consistent with a selective pressure from the mechanical properties of the vertebrate bloodstream environment; trypanosomatid size showed limits relative to host erythrocyte dimensions. This is the first comprehensive analysis of the limits of morphological diversity in any protozoan parasite, revealing the morphogenetic constraints and extrinsic selection pressures associated with the full diversity of trypanosomatid morphology.

  14. Limitations on progress in developing uranium resources

    International Nuclear Information System (INIS)

    Full text: Their exists a gap between the supply of uranium to nuclear power plants and the current demand for uranium for nuclear power plants. Recently rising spot and long term uranium prices provide indication that the supply of previously mined uranium is nearing an irreducible and unavailable inventory. The gap between supply and demand is very large and the inventory of proposed new mines is quite small. There clearly is a need for new uranium production and exploration, as well as increased access to previously mined uranium inventory. The author reviews the limitations to the development of new uranium sources including limitations to access to the existing inventory. The author will discuss the major limitations to progress in finding and developing uranium resources and in the availability of previously mined uranium. The major areas discussed are: 1. Financing of new production sources and new uranium mining companies, 2. Financing of uranium exploration, 3. International Legal Barriers, 4. Political and Social Constraints on Exploration and Production. 5. Environmental and Operational Permitting of Exploration, Development and Production, 6. Motivation of Uranium Producers. 7. Experienced Personnel, 8. Limitations on Developing New Techniques and Equipment to Improve the Accessibility of Uranium Resources Economically. The author will discuss these factors in relation to each of the major uranium producing countries with specific examples from each of the major producing countries to illustrate the limitations. The author will summarize the limitations and suggest the basis for overcoming these limitations as a conclusion to this paper. (author)

  15. Extreme Physics and Informational/Computational Limits

    Energy Technology Data Exchange (ETDEWEB)

    Di Sia, Paolo, E-mail: paolo.disia@univr.it, E-mail: 10alla33@virgilio.it [Department of Computer Science, Faculty of Science, Verona University, Strada Le Grazie 15, I-37134 Verona (Italy) and Faculty of Computer Science, Free University of Bozen, Piazza Domenicani 3, I-39100 Bozen-Bolzano (Italy)

    2011-07-08

    A sector of the current theoretical physics, even called 'extreme physics', deals with topics concerning superstring theories, multiverse, quantum teleportation, negative energy, and more, that only few years ago were considered scientific imaginations or purely speculative physics. Present experimental lines of evidence and implications of cosmological observations seem on the contrary support such theories. These new physical developments lead to informational limits, as the quantity of information, that a physical system can record, and computational limits, resulting from considerations regarding black holes and space-time fluctuations. In this paper I consider important limits for information and computation resulting in particular from string theories and its foundations.

  16. Cosmological Background torsion limits from Lorentz violation

    CERN Document Server

    Garcia de Andrade, L C

    2001-01-01

    Cosmological limits on Lorentz invariance breaking in Chern-Simons $(3+1)-dimensional$ electrodynamics are used to place limits on torsion. Birefrigence phenomena is discussed by using extending the propagation equation to Riemann-Cartan spacetimes instead of treating it in purely Riemannian spaces. The parameter of Lorentz violation is shown to be proportional to the axial torsion vector which allows us to place a limit on cosmological background torsion from the Lorentz violation constraint which is given by $ 10^{-33} eV <|S^{\\mu}| < 10^{-32} eV$ where $|S^{\\mu}|$ is the axial torsion vector.

  17. Limit theorems for 2D invasion percolation

    CERN Document Server

    Damron, Michael

    2010-01-01

    We prove limit theorems and variance estimates for quantities related to ponds and outlets for 2D invasion percolation. We first exhibit several properties of a sequence (O(n)) of outlet variables, the n-th of which gives the number of outlets in the box centered at the origin of side length 2^n. The most important of these properties describe the sequence's renewal structure and exponentially fast mixing behavior. We use these to prove a central limit theorem and strong law of large numbers for (O(n)). We then show consequences of these limit theorems for the pond radii and outlet weights.

  18. Inviscid incompressible limits on expanding domains

    OpenAIRE

    Feireisl, E.; Nečasová, Š. (Šárka); Y. Sun

    2014-01-01

    We consider the inviscid incompressible limit of the compressible Navier-Stokes system on a large domain, the radius of which becomes infinite in the asymptotic limit. We show that the limit solutions satisfy the incompressible Euler system on the whole physical space R3 as long as the radius of the domain is larger than the speed of acoustic waves inversely proportional to the Mach number. The rate of convergence is estimated in terms of the Mach and Reynolds numbers and the radius of the fa...

  19. Limits on Pauli principle violation by nucleons

    CERN Document Server

    Baron, E A; Teplitz, V L

    1999-01-01

    We consider nuclei produced in core collapse supernovae and subjected to a high neutron flux. We show that an accelerator mass spectrometry experiment that searched for traces of anomalous iron isotopes could set limits on the order of $10^{-20}-10^{-25}$ on (or perhaps discover) Pauli principle violation by neutrons. A similar search for anomalous Co isotopes could set limits in the range $10^{-13}-10^{-18}$ on Pauli principle violation by protons. We show that existing data on Oxygen can be used to set a limit of about $10^{-17}$ in one proposed model of such violation.

  20. Fractional Diffusion Limit for Collisional Kinetic Equations

    KAUST Repository

    Mellet, Antoine

    2010-08-20

    This paper is devoted to diffusion limits of linear Boltzmann equations. When the equilibrium distribution function is a Maxwellian distribution, it is well known that for an appropriate time scale, the small mean free path limit gives rise to a diffusion equation. In this paper, we consider situations in which the equilibrium distribution function is a heavy-tailed distribution with infinite variance. We then show that for an appropriate time scale, the small mean free path limit gives rise to a fractional diffusion equation. © 2010 Springer-Verlag.

  1. Noiseless limit of a ferrofluid ratchet

    OpenAIRE

    Becker, Volker; Engel, Andreas

    2004-01-01

    The noiseless limit of a thermal ratchet device using ferrofluids is studied in detail. Contrary to previous claims it is proved that no directed transport can occur in this model in the absence of fluctuations.

  2. Operational limits and disruptions in tokamaks

    International Nuclear Information System (INIS)

    This report contains a concise description on status of knowledge in the area of operational limits and disruption characteristics, based on the results of workshops held during the ITER Definition Phase (1988). (author)

  3. Intensity limitations in compact Hminus cyclotrons

    International Nuclear Information System (INIS)

    At TRIUMF, we have demonstrated 2.5 mA in a compact H- cyclotron. It is worthwhile to explore possibility of going to even higher intensity. In small cyclotrons, vertical focusing vanishes at the center. The space charge tune shift further reduces vertical focusing, thus determining an upper limit on instantaneous current. Limit on average current is of course also dependent upon phase acceptance, but this can be made quite large in an H- cyclotron. Longitudinal space charge on the first turn can reduce the phase acceptance as well. For finite ion source brightness, another limit comes from bunching efficiency in presence of space charge forces. We present methods of calculating and optimizing these limits. In particular, we show that it is possible to achieve 10mA in a 50 MeV compact H- cyclotron

  4. The computation of Buehler confidence limits

    Institute of Scientific and Technical Information of China (English)

    FANG; Xiangzhong; CHEN; Jiading

    2005-01-01

    In medicine and industry, small sample size often arises owing to the high test cost. Then exact confidence inference is important. Buehler confidence limit is a kind of exact confidence limit for the function of parameters in a model. It can be always defined if the order in sample space is given. But the computing problem is often difficult, especially for the cases with high dimension parameter or with incomplete data. This paper presents an algorithm to compute the Buehler confidence limits by EM algorithm. This is the firsttime usage of EM algorithm on Buehler confidence limits, but the algorithm is often used for maximum likelihood estimate in literatures. Three computation examples are given to illustrate the method.

  5. Health Outcomes Survey - Limited Data Set

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Medicare Health Outcomes Survey (HOS) limited data sets (LDS) are comprised of the entire national sample for a given 2-year cohort (including both respondents...

  6. Southern Hemisphere Ice Limits, 1973-1978

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Weekly Southern Ocean ice limits, have been digitized from U.S. Navy Fleet Weather Facility ice charts, at the Max-Planck Institut fur Meteorologie, Hamburg....

  7. 26 CFR 1.851-2 - Limitations.

    Science.gov (United States)

    2010-04-01

    ... TAXES Regulated Investment Companies and Real Estate Investment Trusts § 1.851-2 Limitations. (a... manufacturing or of any other general classification of industry, but issuers shall be construed to be...

  8. Limitations of science and adaptive management

    Energy Technology Data Exchange (ETDEWEB)

    Narasimhan, T.N.

    2001-12-20

    Adaptive management consists in patterning human sustenancewithin the constraints of Earth and biological systems whose behavior isinherently uncertain and difficult to control. For successful adaptivemanagement, a mind-set recognizing the limitations of science isneeded.

  9. Limit Theorems in Free Probability Theory I

    OpenAIRE

    Chistyakov, G. P.; Götze, F.

    2006-01-01

    Based on a new analytical approach to the definition of additive free convolution on probability measures on the real line we prove free analogs of limit theorems for sums for non-identically distributed random variables in classical Probability Theory.

  10. Limiting Spectral Distribution of Sample Autocovariance Matrices

    CERN Document Server

    Basak, Anirban; Sen, Sanchayan

    2011-01-01

    The empirical spectral distribution (ESD) of the sample variance covariance matrix of i.i.d. observations under suitable moment conditions converges almost surely as the dimension tends to infinity. The limiting spectral distribution (LSD) is universal and is known in closed form with support [0, 4]. In this article we show that the ESD of the sample autocovariance matrix converges as the dimension increases, when the time series is a linear process with reasonable restriction on the coefficients. This limit does not depend on the distribution of the underlying driving i.i.d. sequence but in contrast to the sample variance covariance matrix, its support is unbounded. The limit moments are certain functions of the autocovariances. This limit is inconsistent in the sense that it does not coincide with the spectral distribution of the theoretical autocovariance matrix. However, if we consider a suitably tapered version of the autocovariance matrix, then its LSD also exists and is consistent. We also discuss the ...

  11. Elastic stability and the limit of strength

    International Nuclear Information System (INIS)

    The upper limit of strength (the ''theoretical strength'') has been an active subject of research and speculation for the better part of a century. The subject has recently become important, for two reasons. First, given recent advances in ab initio techniques and computing machines, the limits of strength can be calculated with considerable accuracy, making this one of the very few problems in mechanical behavior that can actually be solved. Second, given recent advances in materials engineering, the limits of strength are being approached in some systems, such as hardened or defect-free films, and their relevance is becoming recognized in others. The present paper discusses some interesting results from recent research on the limits of strength, with an intermixture of speculations based on those results. Topics include the inherent nature of {100} cleavage and ''pencil slip'' in bcc metals, the inherent ductility of fcc metals, the anomalous properties of Al, and the possibility of measuring ideal strength with nanoindentation

  12. Low-frequency limit of gravitational scattering

    International Nuclear Information System (INIS)

    We consider the low-frequency limit of cross sections for massless scalar, electromagnetic, and gravitational waves scattering on a Schwarzschild black hole. Explicit results are found for the scattering amplitudes, which differ from the Born approximation results

  13. Recognizing limitations in eddy current testing

    International Nuclear Information System (INIS)

    This paper addresses known limitations and constraints in eddy current nondestructive testing. Incomplete appreciation for eddy current limitations is believed to have contributed to both under-utilization and misapplication of the technique. Neither situation need arise if known limitations are recognized. Some, such as the skin depth effect, are inherent to electromagnetic test methods and define the role of eddy current testing. Others can be overcome with available technology such as surface probes to find circumferential cracks in tubes and magnetic saturation of ferromagnetic alloys to eliminate permeability effects. The variables responsible for limitations in eddy current testing are discussed and where alternative approaches exist, these are presented. Areas with potential for further research and development are also identified

  14. Optical limiting by chemically enhanced bacteriorhodopsin films

    Science.gov (United States)

    Song, Q. Wang; Zhang, Chungping; Gross, Richard; Birge, Robert

    1993-05-01

    Measurements of effective nonlinearity of a chemically enhanced bacteriorhodopsin film are presented, using 2-scan method. Optical limiting properties and the film's nonlinear transmission properties of the film are also studied.

  15. 48 CFR 16.301-3 - Limitations.

    Science.gov (United States)

    2010-10-01

    ... cost-reimbursement contracts is prohibited for the acquisition of commercial items (see parts 2 and 12). ... AND CONTRACT TYPES TYPES OF CONTRACTS Cost-Reimbursement Contracts 16.301-3 Limitations. (a) A...

  16. Limitations of science and adaptive management

    OpenAIRE

    Narasimhan, T. N.

    2001-01-01

    Adaptive management consists in patterning human sustenance within the constraints of Earth and biological systems whose behavior is inherently uncertain and difficult to control. For successful adaptive management, a mind-set recognizing the limitations of science is needed.

  17. Scallop License Limitation Program (SLLP) Permit Program

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A federal Scallop License Limitation Program (SLLP) license is required onboard any vessel deployed in scallop fisheries in Federal waters off Alaska (except for...

  18. 12 CFR 32.3 - Lending limits.

    Science.gov (United States)

    2010-01-01

    ... limit. When the amount due under the grazing contract is dependent upon future performance, the... proceed directly against the equipment and the lessee for any deficiency resulting from the sale of...

  19. Sensitivity Limitations for Multivariable Linear Filtering

    Directory of Open Access Journals (Sweden)

    Steven R. Weller

    2007-01-01

    Full Text Available This paper examines fundamental limitations in performance which apply to linear filtering problems associated with multivariable systems having as many inputs as outputs. The results of this paper quantify unavoidable limitations in the sensitivity of state estimates to process and measurement disturbances, as represented by the maximum singular values of the relevant transfer matrices. These limitations result from interpolation constraints imposed by open right half-plane poles and zeros in the transfer matrices linking process noise and output noise with state estimates. Using the Poisson integral inequality, this paper shows how sensitivity limitations and tradeoffs in multivariable filtering problems are intimately related to the directionality properties of the open right half-plane poles and zeros in these transfer matrices.

  20. Synchronization limit of weakly forced nonlinear oscillators

    International Nuclear Information System (INIS)

    Nonlinear oscillators exhibit synchronization (injection-locking) to external periodic forcings, which underlies the mutual synchronization in networks of nonlinear oscillators. Despite its history of synchronization and the practical importance of injection-locking to date, there are many important open problems of an efficient injection-locking for a given oscillator. In this work, I elucidate a hidden mechanism governing the synchronization limit under weak forcings, which is related to a widely known inequality; Hölder's inequality. This mechanism enables us to understand how and why the efficient injection-locking is realized; a general theory of synchronization limit is constructed where the maximization of the synchronization range or the stability of synchronization for general forcings including pulse trains, and a fundamental limit of general m : n phase locking, are clarified systematically. These synchronization limits and their utility are systematically verified in the Hodgkin–Huxley neuron model as an example. (fast track communication)

  1. Limiting currents in shielded source configurations

    International Nuclear Information System (INIS)

    Limiting currents for laminar flow equilibria of relativistic electron beams in shielded source configurations are discussed. Results are presented for the constant applied magnetic field case, and for the case of constant beam radius

  2. Cities, Towns and Villages - City Limit (polygon)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Data available online through GeoStor at http://www.geostor.arkansas.gov. Arkansas Cities: This data set contains all of the city limit boundaries within the state...

  3. Stable convergence and stable limit theorems

    CERN Document Server

    Häusler, Erich

    2015-01-01

    The authors present a concise but complete exposition of the mathematical theory of stable convergence and give various applications in different areas of probability theory and mathematical statistics to illustrate the usefulness of this concept. Stable convergence holds in many limit theorems of probability theory and statistics – such as the classical central limit theorem – which are usually formulated in terms of convergence in distribution. Originated by Alfred Rényi, the notion of stable convergence is stronger than the classical weak convergence of probability measures. A variety of methods is described which can be used to establish this stronger stable convergence in many limit theorems which were originally formulated only in terms of weak convergence. Naturally, these stronger limit theorems have new and stronger consequences which should not be missed by neglecting the notion of stable convergence. The presentation will be accessible to researchers and advanced students at the master's level...

  4. Energy resolution limits of amplified scintillators

    International Nuclear Information System (INIS)

    In this paper, we analyze the potential improvement in the statistical limit to the energy resolution of a scintillator using a scintillator amplification technique. The work excludes potentially complicating factors, such as non-linearity in light yield, since these factors are dependent upon the particular choice of detector materials. The results show that energy resolutions typical of semiconductors are technically feasible for scintillators. In the example presented, introducing scintillation multiplication improved the energy resolution limit from a few percent to below 1%.

  5. Compression limits in cascaded quadratic soliton compression

    DEFF Research Database (Denmark)

    Bache, Morten; Bang, Ole; Krolikowski, Wieslaw;

    2008-01-01

    Cascaded quadratic soliton compressors generate under optimal conditions few-cycle pulses. Using theory and numerical simulations in a nonlinear crystal suitable for high-energy pulse compression, we address the limits to the compression quality and efficiency.......Cascaded quadratic soliton compressors generate under optimal conditions few-cycle pulses. Using theory and numerical simulations in a nonlinear crystal suitable for high-energy pulse compression, we address the limits to the compression quality and efficiency....

  6. MMSE Limitations of Subband Adaptive Equalisers

    OpenAIRE

    Mohamad, H.; Weiss, S.; Rupp, M.

    2002-01-01

    In this contribution, we investigate limitations of the minimum mean square error (MMSE) solution for subband adaptive equalisers due to aliasing and error in power complementarity. By deriving the Wiener solution for the subband equaliser and comparing it against simulations, we verify that aliasing caused in the subband decimation can be considered equivalent to channel noise. We discuss how these limitations can be mitigated by careful system design.

  7. Gulf of Mexico mud toxicity limitations

    Energy Technology Data Exchange (ETDEWEB)

    Dunn, H.E.; Beardmore, D.H. (Phillips Petroleum Co., Bartlesville, OK (USA)); Stewart, W.S. (Drilling Specialties Co. (US))

    1989-10-01

    Because of the Environmental Protection Agency's recent toxicity limits on drilling mud discharges for offshore Gulf of Mexico, Phillips Petroleum conducted a mud toxicity study based on both field and lab tests. The study, discussed in this article, found the polyanionic cellulose-sulfomethylated quebracho-chrome lignosulfonate mud Phillips had been using would comfortably pass the toxicity limitations. The study also found barite and thinners were of low toxicity, and hydrocarbons and surfactants were highly toxic.

  8. Computer modelling of superconductive fault current limiters

    Energy Technology Data Exchange (ETDEWEB)

    Weller, R.A.; Campbell, A.M.; Coombs, T.A.; Cardwell, D.A.; Storey, R.J. [Cambridge Univ. (United Kingdom). Interdisciplinary Research Centre in Superconductivity (IRC); Hancox, J. [Rolls Royce, Applied Science Division, Derby (United Kingdom)

    1998-05-01

    Investigations are being carried out on the use of superconductors for fault current limiting applications. A number of computer programs are being developed to predict the behavior of different `resistive` fault current limiter designs under a variety of fault conditions. The programs achieve solution by iterative methods based around real measured data rather than theoretical models in order to achieve accuracy at high current densities. (orig.) 5 refs.

  9. The Fragility of Limit Order Markets

    OpenAIRE

    Alasdair Brown

    2013-01-01

    Limit order markets - where a subset of traders provide liquidity on a discretionary basis - are the dominant exchange mechanism for financial assets. We analyse the resilience of these markets using Betfair limit order book trading on the Wimbledon Tennis Championships. As matches go inplay, the risk involved in liquidity provision intensifies, as the value of bets can change substantially in a matter of seconds, and, at the end of the match, certain bets are worthless. Our headline result i...

  10. Supply and demand law under limited information

    OpenAIRE

    Zhang, Yi-Cheng

    2005-01-01

    We present a model for the supply-demand law with quality and limited information capability. We postulate that imperfect information permeates in almost all economic transactions to varying degrees. Through a simple model we outline a research agenda that re-examines many standard issues in economics. Our analysis shows that whereas imperfect information can be improved, it leads to new uncertainties so that the perfect information limit can never be reached. As a corollary neoclassical perf...

  11. Inviscid incompressible limits on expanding domains

    Czech Academy of Sciences Publication Activity Database

    Feireisl, Eduard; Nečasová, Šárka; Sun, Y.

    2014-01-01

    Roč. 27, č. 10 (2014), s. 2465-2477. ISSN 0951-7715 R&D Projects: GA ČR GA13-00522S Institutional support: RVO:67985840 Keywords : compressible Navier-Stokes system * large domain * inviscid limit * incompressible limit Subject RIV: BA - General Mathematics Impact factor: 1.208, year: 2014 http://iopscience.iop.org/0951-7715/27/10/2465/

  12. DNBR limit calculation by sampling statistical method

    International Nuclear Information System (INIS)

    The parametric uncertainties of DNBR and exit quality were calculated using sampling statistical method based on Wilks formula and VIPRE-W code. Then the DNBR design limit and exit quality limit were got by combining with the uncertainties of models and DNB correlation. This method can gain the more DNBR margin than RTDP methodology which is developed by Westinghouse by comparison of these two methods. (authors)

  13. Revisiting Uraltsev's BPS limit for Heavy Quarks

    CERN Document Server

    Heinonen, Johannes

    2016-01-01

    Motivated by the recent experimental data of the values of the Heavy Quark Expansion parameters, in particular the spin-orbit and Darwin terms, we argue that nature actually may be close to a limit of QCD which has been suggested by Uraltsev more than ten years ago. Assuming that this limit is not accidental, we derive the relations among the Heavy Quark Expansion parameters that occur up to the order 1/mb^5.

  14. Activity limitation in joint hypermobility syndrome.

    OpenAIRE

    Schmidt, A.

    2008-01-01

    This review examines the role of fear and avoidance in chronic pain, focusing in particular on their role in activity limitation. It examines the existing fear-avoidance models, in particular Vlaeyen and Linton's (2000) model, it reviews the evidence for this model, and considers it in the context of models of fear and avoidance in other psychological disorders. Evidence is reviewed for other factors which contribute to activity limitation in chronic pain. In the context of this evidence, it ...

  15. The Separate Universe Approach to Soft Limits

    CERN Document Server

    Kenton, Zachary

    2016-01-01

    We develop a formalism for calculating soft limits of $n$-point inflationary correlation functions using separate universe techniques. Our method naturally allows for multiple fields and leads to an elegant diagrammatic approach. As an application we focus on the trispectrum produced by inflation with multiple light fields, giving explicit formulae for all possible single- and double-soft limits. We also investigate consistency relations and present an infinite tower of inequalities between soft correlation functions which generalise the Suyama-Yamaguchi inequality.

  16. LIMITING BEHAVIOR OF UNIFORM RECURSIVE TREES

    Institute of Scientific and Technical Information of China (English)

    Su Chun; Feng Qunqiang; Liu Jie

    2007-01-01

    The authors consider the limiting behavior of various branches in a uniform recursive tree with size growing to infinity. The limiting distribution of ζn,m, the number of branches with size m in a uniform recursive tree of order n, converges weakly to a Poisson distribution with parameter 1/m with convergence of all moments. The size of any large branch tends to infinity almost surely.

  17. Bureaucratic limits of firm size: Academic summary

    OpenAIRE

    Staffan Canback

    2003-01-01

    The research tests Oliver Williamson’s proposition that transaction cost economics can explain the limits of firm size. Williamson suggests that diseconomies of scale are manifested through four interrelated factors: atmospheric consequences due to specialisation, bureaucratic insularity, incentive limits of the employment relation and communication distortion due to bounded rationality. Furthermore, Williamson argues that diseconomies of scale are counteracted by economies of scale and can b...

  18. Environmental radiation standards and risk limitation

    International Nuclear Information System (INIS)

    The Environmental Protection Agency and Nuclear Regulatory Commission have established environmental radiation standards for specific practices which correspond to limits on risk to the public that vary by several orders of magnitude and often are much less than radiation risks that are essentially unregulated, e.g., risks from radon in homes. This paper discusses a proposed framework for environmental radiation standards that would improve the correspondence with limitation of risk. This framework includes the use of limits on annual effective dose equivalent averaged over a lifetime, rather than limits on dose equivalent to whole body or any organ for each year of exposure, and consideration of exposures of younger age groups as well as adults; limits on annual effective dose equivalent averaged over a lifetime no lower than 0.25 mSv (25 mrem) per practice; maintenance of all exposures as low as reasonably achievable (ALARA); and establishment of a generally applicable de minimis dose for public exposures. Implications of the proposed regulatory framework for the current system of standards for limiting public exposures are discussed. 20 refs

  19. Cryogenic Dark Matter Search: limits and projections

    International Nuclear Information System (INIS)

    The results from the second run of the Cryogenic Dark Matter Search experiment in the Soudan Underground Laboratory yields new exclusion limits on the coherent WIMPnucleon scalar cross-sections for WIMP masses above 15 GeV/c2. Two towers, each consisting of six detectors, were operated in the mine for 74.5 live days, doubling the previous Ge exposure to 34 kg-d after cuts for recoil energies of 10-100 keV. When combined with the data from the first run at Soudan, the new upper limit is 1.6 x 10-43 cm2 for a 60 GeV WIMP using the standard dark-matter halo and nuclear physics WIMP model. This is a factor of 2.5 lower than our previous limit and a factor of 10 lower than any other experiment. Limits from the Si data (12 kg-d) are less stringent, but extend the excluded region for low mass WIMPs. CDMS also has sensitivity to spin-dependent limits

  20. Derivation of limit values for nonionising radiation

    International Nuclear Information System (INIS)

    The first limit values for nonionising radiation were introduced in the USSR in 1959. They largely applied to the microwave range. Although the determination of limit values falls within the sovereignty of national governments, international recommendations today play a major role in this. Thus various organisations have dealt with this topic over the past decades. The most noteworthy in matters concerning nonionising radiation is the International Commission on Non-Ionizing Radiation Protection (ICNIRP), the most important task of which is to make recommendations for guides to limiting human exposure over the entire electromagnetic spectrum. It emerged from a working group of the International Radiation Protection Association (IRPA) and has been an independent international organisation with widely branching international partnerships. Among its partners are the World Health Organisation (WHO), the European Commission (EU) and the International Labour Organisation (ILO). The ICNIRP's special status is owed to its recognition by these partners and is reflected in the application of its limit value proposals within the partner organisations' respective spheres of competence. Examples are the EU Council Recommendation on the limitation of exposure of the general public to electromagnetic fields and various labour protection Directives in this area. In Germany the ICNIRP's recommendations have been implemented in labour protection regulations, in telecommunication laws and the 26th Emission Control Ordinance. The present deliberations are therefore based primarily on the ICNIRP's philosophy and on the ongoing discussion of general principles within the international EMF project of the WHO

  1. Limiting factors in caribou population ecology

    Directory of Open Access Journals (Sweden)

    David R. Klein

    1991-10-01

    Full Text Available Caribou and wild reindeer populations fluctuate over time. On this fact there is general agreement. Factors responsible for population limitation and subsequent declines have been examined within the framework of animal population theory. There is, however, little agreement when factors limiting specific populations are generalized to Rangifer populations over broad geographic regions. Comparative examinations of wild Rangifer populations worldwide discloses that factors that have regulated those populations are highly variable between populations, apparently as a reflection of the differences in environmental variables unique to each population. Examples exist of populations where major regulating factors have been climatic extremes, predation, hunting mortality, food limitation, insects, parasites, disease, interspecific competition, and human developmental impacts or combinations of these factors. This diversity of limiting factors affecting caribou and wild reindeer populations is a reflection of the ecologial complexity of the species, a concept that has often been ignored in past efforts to reach management decisions by extrapolation from the limited localized knowledge available on the species.

  2. Beyond the diffraction limit via optical amplification

    CERN Document Server

    Kellerer, Aglae N

    2016-01-01

    In a previous article we suggested a method to overcome the diffraction limit behind a telescope. We refer to theory and recent numerical simulations, and test whether it is indeed possible to use photon amplification to enhance the angular resolution of a telescope or a microscope beyond the diffraction limit. An essential addition is the proposal to select events with above-average ratio of stimulated to spontaneous photons. We find that the diffraction limit of a telescope is surpassed by a factor ten for an amplifier gain of 200, if the analysis is restricted to a tenth of the incoming astronomical photons. A gain of 70 is sufficient with a hundredth of the photons.

  3. Performance limits for Synthetic Aperture Radar.

    Energy Technology Data Exchange (ETDEWEB)

    Doerry, Armin Walter

    2006-02-01

    The performance of a Synthetic Aperture Radar (SAR) system depends on a variety of factors, many which are interdependent in some manner. It is often difficult to ''get your arms around'' the problem of ascertaining achievable performance limits, and yet those limits exist and are dictated by physics, no matter how bright the engineer tasked to generate a system design. This report identifies and explores those limits, and how they depend on hardware system parameters and environmental conditions. Ultimately, this leads to a characterization of parameters that offer optimum performance for the overall SAR system. For example, there are definite optimum frequency bands that depend on weather conditions and range, and minimum radar PRF for a fixed real antenna aperture dimension is independent of frequency. While the information herein is not new to the literature, its collection into a single report hopes to offer some value in reducing the ''seek time''.

  4. The Filter Dichotomy and medial limits

    CERN Document Server

    Larson, Paul B

    2010-01-01

    The \\emph{Filter Dichotomy} says that every uniform nonmeager filter on the integers is mapped by a finite-to-one function to an ultrafilter. The consistency of this principle was proved by Blass and Laflamme. A function between topological spaces is \\emph{universally measurable} if the preimage of %every open subset of the codomain is measured by every Borel measure on the domain. A \\emph{medial limit} is a universally measurable function from $\\mathcal{P}(\\omega)$ to the unit interval [0,1] which is finitely additive for disjoint sets, and maps singletons to 0and $\\omega$ to 1. Christensen and Mokobodzki independently showed that the Continuum Hypothesis implies the existence of medial limits. We show that the Filter Dichotomy implies that there are no medial limits.

  5. Numerical Limit Analysis of Reinforced Concrete Structures

    DEFF Research Database (Denmark)

    Larsen, Kasper Paaske

    For more than half a century, limit state analysis based on the extremum principles have been used to assess the load bearing capacity of reinforced concrete structures. Extensi- ve research within the field has lead to several techniques for performing such analysis manually. While these manual...... limit state analysis problems. The work focuses on determination of the load bearing capacity of reinforced concrete structures by employing the lower bound theorem and a finite element method using equilibrium elements is developed. The recent year’s development within the field of convex optimization...... is applied to solve the limit state problems. Three different element types have been developed and tested. The first is a solid tetra- hedral element with a linear stress distribution. The tri-axial stress state in the element is decomposed into concrete and reinforcement stresses, to which separate...

  6. Lower limits of detection of contamination detectors

    International Nuclear Information System (INIS)

    The new German Radiation Protection Ordinance, which entered into force on April 01, 1977, indicates limits for protective measures to be taken in cases of surface contamination at work stations and of objects, which are very low. In addition, it is provided that persons working in areas containing unsealed radioactive sources be examined for contamination of the skin and clothes. Such checks are to be made as soon as these persons leave the areas referred to above. The imits stated for the skin are even lower than those quoted for the clothes outside controlled plant areas. Accordingly, the question arises in many cases whether the detectors used so far, or to be newly purchased, are capable of detecting surface contamination ot the order of, or even below, these limits. This contribution is to help in assessing contamination detectors with respect to their lower limits of detection. (orig.)

  7. The financial-economical risk limit

    International Nuclear Information System (INIS)

    This report makes part of a series of eight reports which have been drawn up in behalf of the dutch Policy Notition Radiation Standards (BNS). In this report the results are presented of an investigation into a financial-economic risk limit. An inventarization has been made of how the concept economical damage is used in various policy domains. It is investigated if therewith use has been made of a financial-economic risk limit. The height of this limit has been assessed. In order to give a checklist of the aspects which have to be taken into account in the calculation of the financial-economic damage, the character of the low probability-high consequence needs to be mentioned nearer. (author). 49 refs.; 4 figs.; 4 tabs

  8. Limited liability and the public's health.

    Science.gov (United States)

    Rutkow, Lainie; Teret, Stephen P

    2007-01-01

    Corporations, through their products and behaviors, exert a strong effect on the well-being of populations. Industries including firearms, motor vehicles, tobacco, and alcohol produce and market products negatively impact public health. All of these industries are composed of corporations, which are legal fictions designed to provide limited exposure to liability, through a variety of mechanisms, for their investors and directors. This means that when actions are taken on behalf of a corporate entity, the individuals responsible generally will not face personal liability for the negative results of those actions. To illustrate this point, this article considers corporate products or practices that have caused harm in varied settings, and analyzes the role that limited liability played in these cases. In addition, the article identifies ways to modify or eliminate some of the principles and practices that accompany limited liability. PMID:18076511

  9. Limitation of computational resource as physical principle

    CERN Document Server

    Ozhigov, Y I

    2003-01-01

    Limitation of computational resources is considered as a universal principle that for simulation is as fundamental as physical laws are. It claims that all experimentally verifiable implications of physical laws can be simulated by the effective classical algorithms. It is demonstrated through a completely deterministic approach proposed for the simulation of biopolymers assembly. A state of molecule during its assembly is described in terms of the reduced density matrix permitting only limited tunneling. An assembly is treated as a sequence of elementary scatterings of simple molecules from the environment on the point of assembly. A decoherence is treated as a forced measurement of quantum state resulted from the shortage of computational resource. All results of measurements are determined by a choice from the limited number of special options of the nonphysical nature which stay unchanged till the completion of assembly; we do not use the random numbers generators. Observations of equal states during the ...

  10. Limiters and first wall on JET

    International Nuclear Information System (INIS)

    During the initial phase of the JET operation, graphite limiters and Inconel wall protection plates had been used. After one year of operation, some of the Inconel plates at the inboard wall were found to be significantly damaged. These plates were replaced by graphite tiles in order to eliminate one source of metallic contamination of the plasma. Operational experience with the graphite tiles has been good, and additional graphite protections have been installed recently. Further protections will be added in 1987 to cover extensively, although not completely, the walls of the vessel. This paper describes the limiters and wall protections used so far, together with the experimental evidence gained during 2 years of operation. It also describes the belt limiter to be installed in the near future, and outlines longer term development plans

  11. Fundamental limitations for quantum and nano thermodynamics

    CERN Document Server

    Horodecki, Michał

    2011-01-01

    The relationship between thermodynamics and statistical physics is valid in the thermodynamic limit -- when the number of particles involved becomes very large. Here we study thermodynamics in the opposite regime -- at both the nano scale, and when quantum effects become important. Applying results from quantum information theory we construct a theory of thermodynamics in these extreme limits. In the quantum regime, we find that the standard free energy no longer determines the amount of work which can be extracted from a resource, nor which state transitions can occur spontaneously. We derive a criteria for thermodynamical state transitions, and find two free energies: one which determines the amount of work which can be extracted from a small system in contact with a heat bath, and the other which quantifies the reverse process. They imply that generically, there are additional constraints which govern spontaneous thermodynamical processes. We find that there are fundamental limitations on work extraction f...

  12. Industry perspective on setting emissions limits

    International Nuclear Information System (INIS)

    GE Hitachi Nuclear Energy Canada Inc. (GEH-C) has operated a uranium dioxide fuel pelletizing plant and fuel bundle assembly facility in Toronto and Peterborough respectively, since the mid- 1960's. A primary operational objective is to ensure a consistently high degree of environmental protection, and to accomplish this requires properly established emission control limits. This paper will summarize the system of environmental and public protection constraints currently in place at GEH-C including derived emission limits, operational limits and action levels. It will discuss the basis of any values chosen and describe the methods used to calculate their magnitude. Perspectives on how to ensure operational effectiveness of these constraints will also be addressed. (authors)

  13. New mass limit of white dwarfs

    CERN Document Server

    Das, Upasana

    2013-01-01

    Is the Chandrasekhar mass limit for white dwarfs (WDs) set in stone? Not anymore -- recent observations of over-luminous, peculiar type Ia supernovae can be explained if significantly super-Chandrasekhar WDs exist as their progenitors, thus barring them to be used as cosmic distance indicators. However, there is no estimate of a mass limit for these super-Chandrasekhar WD candidates yet. Can they be arbitrarily large? In fact, the answer is no! We arrive at this revelation by exploiting the flux freezing theorem in observed, accreting, magnetized WDs, which brings in Landau quantization of the underlying electron degenerate gas. This essay presents the calculations which pave the way for the ultimate (significantly super-Chandrasekhar) mass limit of WDs, heralding a paradigm shift 80 years after Chandrasekhar's discovery.

  14. Thermal Nature of Concentration Limits of Combustion

    Science.gov (United States)

    Sabdenov, K. O.; Baitasov, T. M.

    2015-05-01

    An explanation is proposed for the concentration limits of slow combustion of gas mixtures due to the diffusional-thermal instability of a flame and the leading role of the thermal effect of mixture combustion. Basic to this explanation are the following experimental facts obtained for a wide class of mixtures: the concentration limits of slow combustion of a mixture and of its detonation are closely coinciding and depend strongly on the stoichiometric composition of mixture; there is an approximate symmetry relation between the upper and lower combustion limits. It is shown that the flame temperature of gas mixtures depends on their stoichiometric composition and that as their stoichiometric relation deviates from unity, the state of mixture combustion approaches the stability threshold beyond which a stationary flame cannot exist.

  15. Long pulse operation with actively cooled limiters

    International Nuclear Information System (INIS)

    We present here the major results obtained with actively cooled plasma facing components during long pulse operation (plasma duration >3 x surface temperature time constant=steady-state). Shots up to 120 s have been achieved in Tore Supra when the plasma was leaning on the large inner toroidal actively cooled limiter with a moderate deposited power density heat flux (up to 0.3 MW/m2). For larger power density heat flux up to 4.5 MW/m2 (design value), modular limiters have been used. A prerequisite for any actively cooled limiter is the absence of any cooling defect (crack parallel to the surface in the tile or non-correct bonding). If a defect is present it leads to a super-brilliance event (with its corresponding local power heat flux increase) which propagates. This deleterious effect is unfortunately a runaway effect. (orig.)

  16. Occupational Exposures and Chronic Airflow Limitation

    Directory of Open Access Journals (Sweden)

    Helen Dimich-Ward

    1996-01-01

    Full Text Available The recent literature was reviewed to evaluate whether chronic airflow limitation is associated with occupational exposures to dusts. Only those studies that controlled for the effects of smoking were included. There is compelling evidence that exposure to inorganic dusts, such as from coal and hardrock mining or asbestos, are associated with the development of chronic airflow limitation, independently of pneumoconiosis. Nonsmoking gold miners are particularly at high risk of airflow obstruction and emphysema. Findings from studies of organic dusts, such as exposures to wood, cotton, grain or other agricultural dusts, or to mixed dust exposures, were less consistent but tended to show positive dose-response associations. In the majority of studies, no statistical interaction was shown between dust exposures and smoking; however, the effects of the dust exposures were often more pronounced. An occupational history should be considered, in addition to a smoking history, as an integral part of an investigation of chronic airflow limitation in a patient.

  17. Limit analysis and design of containment vessels

    International Nuclear Information System (INIS)

    In the introduction, the theory of plastic analysis of shells is briefly recalled. Minimum-volume design for assigned load factor at plastic collapse is then considered and optimality criteria are derived for plates and shells of continuously varying or piecewise-constant thickness. In the first part, containers made of metal are examined. Analytical and numerical limit analysis solutions and corresponding experimental results are considered for various types of vessels, including intersecting shells. Attention is given to experimental post-yield behavior. Some tests up to fracture are discussed. New theoretical and experimental results of limit analysis of stiffened cylindrical vessels are presented, in which reinforcing rings are treated as discrete structural element (no smearing out) and due account is taken of their strong curvature. Cases of collapse by instability under internal pressure are pointed out. Minimum-volume design of circular plates and cylindrical shells is then formulated and various examples are presented of sandwich and solid metal structures. Containers of piecewise-constant thickness are given particular attention. Available experimental evidence on minimum-volume design of plates and shells is reviewed and commented upon. The second part deals with reinforced concrete vessels. Cylindrical containers are studied, from both points of view of limit analysis and of limit design with minimum volume of reinforcement. The practical use of the latter solutions is discussed. A third part reviews other loading cases (including cyclic and impact loads) and gives indications on corresponding theories, formulations and solution methods. The last part is devoted to a discussion of the limitations of the methods presented, within the frame of the 'limit states' design philosophy, which is first briefly recalled. Considerations on further research in the field conclude the paper. (orig.)

  18. Limits on Non-Linear Electrodynamics

    OpenAIRE

    Fouché, M.; Battesti, R.; Rizzo, C

    2016-01-01

    In this paper we set a framework in which experiments whose goal is to test QED predictions can be used in a more general way to test non-linear electrodynamics (NLED) which contains low-energy QED as a special case. We review some of these experiments and we establish limits on the different free parameters by generalizing QED predictions in the framework of NLED. We finally discuss the implications of these limits on bound systems and isolated charged particles for which QED has been widely...

  19. Computability limits non-local correlations

    OpenAIRE

    Islam, Tanvirul; Wehner, Stephanie

    2012-01-01

    If the no-signalling principle was the only limit to the strength of non-local correlations, we would expect that any form of no-signalling correlation can indeed be realized. That is, there exists a state and measurements that remote parties can implement to obtain any such correlation. Here, we show that in any theory in which some functions cannot be computed, there must be further limits to non-local correlations than the no-signalling principle alone. We proceed to argue that even in a t...

  20. Self-Similarity Limits of Genomic Signatures

    CERN Document Server

    Wu, Z B

    2002-01-01

    It is shown that metric representation of DNA sequences is one-to-one. By using the metric representation method, suppression of nucleotide strings in the DNA sequences is determined. For a DNA sequence, an optimal string length to display genomic signature in chaos game representation is obtained by eliminating effects of the finite sequence. The optical string length is further shown as a self- similarity limit in computing information dimension. By using the method, self-similarity limits of bacteria complete genomic signatures are further determined.