WorldWideScience

Sample records for bioscience grand challenge

  1. The interfacial bioscience grand challenge.

    Energy Technology Data Exchange (ETDEWEB)

    Lane, Pamela; Stevens, Mark Jackson; Jacobsen, Richard B.; Hong, Joohee; Ayson, Marites J.; Crozier, Paul Stewart; Wood, Nichole L.; Schoeniger, Joseph S.; Kruppa, Gary Hermann; Sale, Kenneth L.; Young, Malin M.; Faulon, Jean-Loup Michel; Burns, Alan Richard; Evans, Kervin O.; Novak, Petr

    2004-03-01

    This report is broken down into the following 3 sections: (1) Chemical Cross-linking and Mass Spectrometry Applied to Determination of Protein Structure and Dynamics; (2) Computational Modeling of Membrane Protein Structure and Dynamics; and (3) Studies of Toxin-Membrane Interactions using Single Molecule Biophysical Methods.

  2. Challenges in Understanding Photosynthesis in a University Introductory Biosciences Class

    Science.gov (United States)

    Södervik, Ilona; Virtanen, Viivi; Mikkilä-Erdmann, Mirjamaija

    2015-01-01

    University students' understanding of photosynthesis was examined in a large introductory biosciences class. The focus of this study was to first examine the conceptions of photosynthesis among students in class and then to investigate how a certain type of text could enhance students' understanding of photosynthesis. The study was based on pre-…

  3. Unpacking the grand challenges of nanotechnology

    OpenAIRE

    Lente, H. van; Bos, C

    2012-01-01

    Important societal themes, such as sustainability or the ageing society, are referred to as 'grand challenges'. During the last decade, many funding programs were set up to address these and other grand challenges. While grand challenges have a moral component – it is difficult to contest that it is 'good' to address them – they do not convey clear-cut goals for action. When they are related to the actual development of new technologies, grand challenges are articulated in different ways. Art...

  4. Grand Challenges of Enterprise Integration

    Energy Technology Data Exchange (ETDEWEB)

    Brosey, W.D; Neal, R.E.; Marks, D.

    2001-04-01

    Enterprise Integration connects and combines people, processes, systems, and technologies to ensure that the right people and the right processes have the right information and the right resources at the right time. A consensus roadmap for Technologies for Enterprise Integration was created as part of an industry/government/academia partnership in the Integrated Manufacturing Technology Initiative (IMTI). Two of the grand challenges identified by the roadmapping effort will be addressed here--Customer Responsive Enterprises and Totally Connected Enterprises. Each of these challenges is briefly discussed as to the current state of industry and the future vision as developed in the roadmap.

  5. Grand challenges in migration biology.

    Science.gov (United States)

    Bowlin, Melissa S; Bisson, Isabelle-Anne; Shamoun-Baranes, Judy; Reichard, Jonathan D; Sapir, Nir; Marra, Peter P; Kunz, Thomas H; Wilcove, David S; Hedenström, Anders; Guglielmo, Christopher G; Åkesson, Susanne; Ramenofsky, Marilyn; Wikelski, Martin

    2010-09-01

    Billions of animals migrate each year. To successfully reach their destination, migrants must have evolved an appropriate genetic program and suitable developmental, morphological, physiological, biomechanical, behavioral, and life-history traits. Moreover, they must interact successfully with biotic and abiotic factors in their environment. Migration therefore provides an excellent model system in which to address several of the "grand challenges" in organismal biology. Previous research on migration, however, has often focused on a single aspect of the phenomenon, largely due to methodological, geographical, or financial constraints. Integrative migration biology asks 'big questions' such as how, when, where, and why animals migrate, which can be answered by examining the process from multiple ecological and evolutionary perspectives, incorporating multifaceted knowledge from various other scientific disciplines, and using new technologies and modeling approaches, all within the context of an annual cycle. Adopting an integrative research strategy will provide a better understanding of the interactions between biological levels of organization, of what role migrants play in disease transmission, and of how to conserve migrants and the habitats upon which they depend. PMID:21558203

  6. Challenges and opportunities for early-career Teaching-Focussed academics in the biosciences.

    Science.gov (United States)

    Hubbard, Katharine; Gretton, Sarah; Jones, Katherine; Tallents, Lucy

    2015-01-01

    Twenty-seven percent of academics in UK Higher Education (HE) are in Teaching-Focussed positions, making major contributions to undergraduate programmes in an era of high student expectations when it comes to teaching quality. However, institutional support for Teaching-Focussed academics is often limited, both in terms of peer networking and opportunities for career development. As four early-career stage Teaching-Focussed academics working in a variety of institutions, we explore what motivated our choices to make teaching our primary academic activity, and the challenges that we have faced in doing so. In addition to highlighting the need for universities to fully recognise the achievements of teaching staff, we discuss the role that the various biosciences learned societies have in supporting Teaching-Focussed academics. We identify that there is a need for the learned societies to come together and pool their expertise in this area. The fragmented nature of the Teaching-Focussed academic community means that clear sources of national support are needed in order to best enable the next generation of bioscience educators to reach their full potential. PMID:25977754

  7. Grand challenges in modeling and simulation

    Science.gov (United States)

    Gordon, Steven C.

    2002-07-01

    Few argue with the need for modeling and simulation (M&S) to better or more completely represent current and expected military operations. The challenge is to decide where to make specific improvements in M&S representation and functionality within time, funding, technology, and research limitations. So, it is natural to select key areas - Grand Challenges - for a significant evolution in M&S where a major effort of many at considerable cost is needed to deal with the critical issues ahead. This paper selects three proposed and related Grand Challenges. First, M&S Depiction of Information and Effects-Based Operations, as a Grand Challenge, will assist in creating sufficiently realistic battlespaces for M&S users. Second, M&S Support to Crisis Response and Military Operations, as a Grand Challenge, is a key area that will help the Department of Defense meet transformation goals. Third, Effective Development of Future Simulations, as a Grand Challenge, will set the standards by which future M&S improvements and new M&S programs will be acquired to ensure needed simulations are delivered on time and at desired cost.

  8. Grand Challenges facing Storage Systems

    CERN Document Server

    CERN. Geneva

    2004-01-01

    In this talk, we will discuss the future of storage systems. In particular, we will focus on several big challenges which we are facing in storage, such as being able to build, manage and backup really massive storage systems, being able to find information of interest, being able to do long-term archival of data, and so on. We also present ideas and research being done to address these challenges, and provide a perspective on how we expect these challenges to be resolved as we go forward.

  9. PUBLIC HEALTH: Grand Challenges in Global Health

    OpenAIRE

    Varmus, H.; Klausner, R; Zerhouni, E.; Acharya, T.; Daar, A S; Singer, P A

    2003-01-01

    This week an international panel announces a list of 14 Grand Challenges in Global Health, and scientists throughout the world will be invited to submit grant proposals to pursue them with funds provided by the Bill & Melinda Gates Foundation. We describe the characteristics of these challenges and the process by which they were formulated and selected after receiving over 1000 responses to a "call for ideas" from the scientific community.

  10. Grand Challenges in Music Information Research

    OpenAIRE

    Goto, Masataka

    2012-01-01

    This paper discusses some grand challenges in which music information research will impact our daily lives and our society in the future. Here, some fundamental questions are how to provide the best music for each person, how to predict music trends, how to enrich human-music relationships, how to evolve new music, and how to address environmental, energy issues by using music technologies. Our goal is to increase both attractiveness and social impacts of music information research in the fut...

  11. Grand challenges in protoplanetary disc modelling

    CERN Document Server

    Haworth, Thomas J; Forgan, Duncan H; Facchini, Stefano; Price, Daniel J; authors, Community; Boneberg, Dominika M; Booth, Richard A; Gonzalez, Jean-François; Hutchison, Mark A; Laibe, Guillaume; Meru, Farzana; Mohanty, Subhanjoy; Panić, Olja; Rice, Ken; Walsh, Catherine; Woitke, Peter

    2016-01-01

    The Protoplanetary Discussions conference --- held in Edinburgh, UK, from 7th-11th March 2016 --- included several open sessions led by participants. This paper reports on the discussions collectively concerned with the multiphysics modelling of protoplanetary discs, including the self-consistent calculation of gas and dust dynamics, radiative transfer and chemistry. After a short introduction to each of these disciplines in isolation, we identify a series of burning questions and grand challenges associated with their integration, which are not necessarily achievable in the short-to-medium term. We then discuss potential pathways towards solving these challenges, grouped by strategical, technical and collaborative developments. This paper is not intended to be a review, but rather to motivate and direct future research and collaboration across typically distinct fields based on community driven input, to encourage further progress in our understanding of circumstellar and protoplanetary discs.

  12. Prospects of solving grand challenge problems

    CERN Document Server

    Gupta, R

    1995-01-01

    The recent woes of the supercomputer industry and changes in federal funding have caused some scientists to re-evaluate the means by which they hope to solve Grand Challenge problems. I evaluate the potential of Massively Parallel Processors (MPP) within this context and the state of today's MPP. I stress that for solving large-scale problems MPP are crucial and that it is essential to seek a balance between CPU performance, memory access time, inter-node communications, and I/O. To achieve this it is important to preserve certain characteristics of the hardware while selecting the hottest processor to design the machine around. I emphasize that for long term stability and growth of parallel computing priority should be given to standardizing software so that the same code can run on different platforms and on machines ranging from clusters of workstations to MPP.

  13. Grand challenges in clinical decision support.

    Science.gov (United States)

    Sittig, Dean F; Wright, Adam; Osheroff, Jerome A; Middleton, Blackford; Teich, Jonathan M; Ash, Joan S; Campbell, Emily; Bates, David W

    2008-04-01

    There is a pressing need for high-quality, effective means of designing, developing, presenting, implementing, evaluating, and maintaining all types of clinical decision support capabilities for clinicians, patients and consumers. Using an iterative, consensus-building process we identified a rank-ordered list of the top 10 grand challenges in clinical decision support. This list was created to educate and inspire researchers, developers, funders, and policy-makers. The list of challenges in order of importance that they be solved if patients and organizations are to begin realizing the fullest benefits possible of these systems consists of: improve the human-computer interface; disseminate best practices in CDS design, development, and implementation; summarize patient-level information; prioritize and filter recommendations to the user; create an architecture for sharing executable CDS modules and services; combine recommendations for patients with co-morbidities; prioritize CDS content development and implementation; create internet-accessible clinical decision support repositories; use freetext information to drive clinical decision support; mine large clinical databases to create new CDS. Identification of solutions to these challenges is critical if clinical decision support is to achieve its potential and improve the quality, safety and efficiency of healthcare. PMID:18029232

  14. The Arctic Grand Challenge: Abrupt Climate Change

    Science.gov (United States)

    Wilkniss, P. E.

    2003-12-01

    Trouble in polar paradise (Science, 08/30/02), significant changes in the Arctic environment are scientifically documented (R.E. Moritz et al. ibid.). More trouble, lots more, "abrupt climate change," (R. B. Alley, et al. Science 03/28/03). R. Corell, Arctic Climate Impact Assessment team (ACIA), "If you want to see what will happen in the rest of the world 25 years from now just look what's happening in the Arctic," (Arctic Council meeting, Iceland, 08/03). What to do? Make abrupt Arctic climate change a grand challenge for the IPY-4 and beyond! Scientifically:Describe the "state" of the Arctic climate system as succinctly as possible and accept it as the point of departure.Develop a hypothesis and criteria what constitutes "abrupt climate change," in the Arctic that can be tested with observations. Observations: Bring to bear existing observations and coordinate new investments in observations through an IPY-4 scientific management committee. Make the new Barrow, Alaska, Global Climate Change Research Facility a major U.S. contribution and focal point for the IPY-4 in the U.S Arctic. Arctic populations, Native peoples: The people of the North are living already, daily, with wrenching change, encroaching on their habitats and cultures. For them "the earth is faster now," (I. Krupnik and D. Jolly, ARCUS, 2002). From a political, economic, social and entirely realistic perspective, an Arctic grand challenge without the total integration of the Native peoples in this effort cannot succeed. Therefore: Communications must be established, and the respective Native entities must be approached with the determination to create well founded, well functioning, enduring partnerships. In the U.S. Arctic, Barrow with its long history of involvement and active support of science and with the new global climate change research facility should be the focal point of choice Private industry: Resource extraction in the Arctic followed by oil and gas consumption, return the combustion

  15. Challenges faced by multidisplinary new investigators on addressing grand challenges in global health

    OpenAIRE

    Logie, Carmen; Dimaras, Helen; Fortin, Anny; Ramón-García, Santiago

    2014-01-01

    Background The grand challenges approach aims to spark innovative and transformative strategies to overcome barriers to significant global health issues. Grand Challenges Canada endorses an ‘Integrated Innovation™’ approach that focuses on the intersection of scientific/technological, social and business innovation. In this article we explore themes emerging from a dialogue between the authors, who are multidisciplinary recipients of the ‘Rising Stars in Global Health’ award from Grand Challe...

  16. Grand Challenges for Global Brain Sciences

    OpenAIRE

    Vogelstein, Joshua T.; Amunts, Katrin; Andreou, Andreas; Angelaki, Dora; Ascoli, Giorgio; Bargmann, Cori; Burns, Randal; Cali, Corrado; Chance, Frances; Chun, Miyoung; Church, George; Cline, Hollis; Coleman, Todd; de La Rochefoucauld, Stephanie; Denk, Winfried

    2016-01-01

    Understanding the brain and curing it are among the most exciting challenges of our time. Consequently, national, transnational, and private parties are investing billions of dollars (USD). To efficiently join forces, Global Brain Workshop 2016 was hosted at Johns Hopkins University's Kavli Neuroscience Discovery Institute on April 7--8. A second workshop, Open Data Ecosystem in Neuroscience took place July 25--26 in DC to continue the discussion specifically about computational challenges an...

  17. Workshop and conference on Grand Challenges applications and software technology

    Energy Technology Data Exchange (ETDEWEB)

    1993-12-31

    On May 4--7, 1993, nine federal agencies sponsored a four-day meeting on Grand Challenge applications and software technology. The objective was to bring High-Performance Computing and Communications (HPCC) Grand Challenge applications research groups supported under the federal HPCC program together with HPCC software technologists to: discuss multidisciplinary computational science research issues and approaches, identify major technology challenges facing users and providers, and refine software technology requirements for Grand Challenge applications research. The first day and a half focused on applications. Presentations were given by speakers from universities, national laboratories, and government agencies actively involved in Grand Challenge research. Five areas of research were covered: environmental and earth sciences; computational physics; computational biology, chemistry, and materials sciences; computational fluid and plasma dynamics; and applications of artificial intelligence. The next day and a half was spent in working groups in which the applications researchers were joined by software technologists. Nine breakout sessions took place: I/0, Data, and File Systems; Parallel Programming Paradigms; Performance Characterization and Evaluation of Massively Parallel Processing Applications; Program Development Tools; Building Multidisciplinary Applications; Algorithm and Libraries I; Algorithms and Libraries II; Graphics and Visualization; and National HPCC Infrastructure.

  18. Grand challenges in space synthetic biology

    OpenAIRE

    Menezes, Amor A.; Montague, Michael G.; Cumbers, John; Hogan, John A.; Arkin, Adam P.

    2015-01-01

    Space synthetic biology is a branch of biotechnology dedicated to engineering biological systems for space exploration, industry and science. There is significant public and private interest in designing robust and reliable organisms that can assist on long-duration astronaut missions. Recent work has also demonstrated that such synthetic biology is a feasible payload minimization and life support approach as well. This article identifies the challenges and opportunities that lie ahead in the...

  19. Grand challenges in space synthetic biology.

    Science.gov (United States)

    Menezes, Amor A; Montague, Michael G; Cumbers, John; Hogan, John A; Arkin, Adam P

    2015-12-01

    Space synthetic biology is a branch of biotechnology dedicated to engineering biological systems for space exploration, industry and science. There is significant public and private interest in designing robust and reliable organisms that can assist on long-duration astronaut missions. Recent work has also demonstrated that such synthetic biology is a feasible payload minimization and life support approach as well. This article identifies the challenges and opportunities that lie ahead in the field of space synthetic biology, while highlighting relevant progress. It also outlines anticipated broader benefits from this field, because space engineering advances will drive technological innovation on Earth. PMID:26631337

  20. Grand Challenges in Clinical Decision Support v10

    OpenAIRE

    Sittig, Dean F.; Wright, Adam; Osheroff, Jerome A; Middleton, Blackford; Teich, Jonathan M.; Ash, Joan S.; Campbell, Emily; Bates, David W.

    2007-01-01

    There is a pressing need for high-quality, effective means of designing, developing, presenting, implementing, evaluating, and maintaining all types of clinical decision support capabilities for clinicians, patients and consumers. Using an iterative, consensus-building process we identified a rank-ordered list of the top 10 grand challenges in clinical decision support. This list was created to educate and inspire researchers, developers, funders, and policy-makers. The list of challenges in ...

  1. Virginia Tech students gearing up for $1 million Grand Challenge

    OpenAIRE

    Crumbley, Liz

    2004-01-01

    A prize of $1 million, a route of 250 miles between Los Angeles and Las Vegas and no human intervention allowed past the starting line -- that's the Grand Challenge awaiting a team of Virginia Tech students and 24 other competitors on March 13. The challenge posed by the competition's sponsor, DARPA (Defense Advanced Research Projects Agency), seems simple -- the winning vehicle will complete a 250-mile designated route between Los Angeles and Las Vegas in less than 10 hours.

  2. Grand Challenges in Measuring and Characterizing Scholarly Impact

    OpenAIRE

    Chen, Chaomei

    2016-01-01

    The constantly growing body of scholarly knowledge of science, technology, and humanities is an asset of the mankind. While new discoveries expand the existing knowledge, they may simultaneously render some of it obsolete. It is crucial for scientists and other stakeholders to keep their knowledge up to date. Policy makers, decision makers, and the general public also need an efficient communication of scientific knowledge. Several grand challenges concerning the creation, adaptation, and dif...

  3. Grand Challenges in Chemistry for 2016 and Beyond

    OpenAIRE

    Bertozzi, Carolyn R.; Chang, Christopher J.; Davis, Benjamin G.; de la Cruz, Monica Olvera; Tirrell, David A.; Zhao, Dongyuan

    2016-01-01

    When several ACS Central Science Editors met for dinner at the 2015 Pacifichem meeting, conversation turned to the grand challenges facing science and society, and those we felt chemistry was in a unique position to solve. With the New Year, we thought we would share our ideas in our first editorial of 2016. The arenas in which we see chemistry having the largest influence are the molecular bases of disease and aging, alternative energy advancement, and the conservatio...

  4. A BLUEPRINT FOR IMPLEMENTING GRAND CHALLENGE SCHOLARS’ PROGRAMME: A CASE STUDY OF TAYLOR’S UNIVERSITY

    OpenAIRE

    MUSHTAK AL-ATABI; DOUGLAS TONG KUM TIEN

    2013-01-01

    The National Academy for Engineering announced 14 Grand Challenges for the 21st Century engineers to address in order to ensure a sustainable future for the generations to come. These grand challenges are in four broad areas, namely, energy and environment, health, security and learning and computation. This paper reports on a Grand Challenges Scholars’ Programme that is developed to prepare the engineering students to be able to address the grand challenges using the CDIO framework and focus...

  5. Fostering Scientific Literacy: Establishing Social Relevance via the Grand Challenges

    Science.gov (United States)

    Lyford, M. E.; Myers, J. D.; Buss, A.

    2010-12-01

    Numerous studies and polls suggest the general public’s understanding of science and scientific literacy remain woefully inadequate despite repeated calls for improvement over the last 150 years. This inability to improve scientific literacy significantly is a complex problem likely driven by a number of factors. However, we argue that past calls and efforts for improving scientific literacy have failed to: 1) articulate a truly meaningful justification for society to foster a scientifically literate public; 2) provide a rationale that motivates individuals of diverse backgrounds to become scientifically literate; 3) consider the impact of personal perspective, e.g. values, beliefs, attitudes, etc., on learning; and 4) offer a relevant and manageable framework in which to define scientific literacy. For instance, past calls for improving scientific literacy, e.g. the U.S. is behind the Soviets in the space race, U.S students rank below country X in math and science, etc., have lacked justification, personal motivation and a comprehensive framework for defining scientific literacy. In these cases, the primary justification for improving science education and scientific literacy was to regain international dominance in the space race or to advance global standing according to test results. These types of calls also articulate short-term goals that are rendered moot once they have been achieved. At the same time, teaching practices have commonly failed to consider the perspectives students bring to the classroom. Many STEM faculty do not address issues of personal perspective through ignorance or the desire to avoid controversial subjects, e g. evolution, climate change. We propose that the ‘grand challenges’ (e.g., energy, climate change, antibacterial resistance, water, etc.) humankind currently faces provides a compelling framework for developing courses and curricula well-suited for improving scientific literacy. A grand challenge paradigm offers four

  6. Bringing Seismology's Grand Challenges to the Undergraduate Classroom

    Science.gov (United States)

    Benoit, M. H.; Taber, J.; Hubenthal, M.

    2011-12-01

    The "Seismological Grand Challenges in Understanding Earth's Dynamic Systems," a community-written long-range science plan for the next decade, poses 10 questions to guide fundamental seismological research. Written in an approachable fashion suitable for policymakers, the broad questions and supporting discussion contained in this document offer an ideal framework for the development of undergraduate curricular materials. Leveraging this document, we have created a collection of inquiry-based classroom modules that utilize authentic data to modernize seismological instruction in 100 and 200 level undergraduate courses. The modules not only introduce undergraduates to the broad questions that the seismological community seeks to answer in the future but also showcase the numerous areas where modern seismological research is actively contributing to our understanding of fundamental Earth processes. To date 6 in-depth explorations that correspond to the Grand Challenges document have been developed. The specific topics for each exploration were selected to showcase modern seismological research while also covering topics commonly included in the curriculum of these introductory classes. Examples of activities that have been created and their corresponding Grand Challenge include: -A guided inquiry that introduces students to episodic tremor and slip and compares the GPS and seismic signatures of ETS with those produced from standard tectonic earthquakes (Grand Challenge "How do faults slip?"). - A laboratory exercise where students engage in b-value mapping of volcanic earthquakes to assess potential eruption hazards (How do magmas ascend and erupt?). - A module that introduce students to glacial earthquakes in Greenland and compares their frequency and spatial distribution to tectonic earthquakes (How do processes in the ocean and atmosphere interact with the solid Earth?). What is the relationship between stress and strain in the lithosphere? - An activity that

  7. The MICE Grand Challenge Lightcone Simulation I: Dark matter clustering

    CERN Document Server

    Fosalba, P; Gaztanaga, E; Castander, F J

    2013-01-01

    We present a new N-body simulation from the MICE collaboration, the MICE Grand Challenge (MICE-GC), containing about 70 billion dark-matter particles in a (3 Gpc/h)^3 comoving volume. Given its large volume and fine spatial resolution, spanning over 5 orders of magnitude in dynamic range, it allows an accurate modeling of the growth of structure in the universe from the linear through the highly non-linear regime of gravitational clustering. We validate the dark-matter simulation outputs using 3D and 2D clustering statistics, and discuss mass-resolution effects in the non-linear regime by comparing to previous simulations and the latest numerical fits. We show that the MICE-GC run allows for a measurement of the BAO feature with percent level accuracy and compare it to state-of-the-art theoretical models. We also use sub-arcmin resolution pixelized 2D maps of the dark-matter counts in the lightcone to make tomographic analyses in real and redshift space. Our analysis shows the simulation reproduces the Kaiser...

  8. Grand challenge problems in environmental modeling and remediation: Groundwater contaminant transport. Final project report 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-04-01

    The over-reaching goal of the Groundwater Grand Challenge component of the Partnership in Computational Science (PICS) was to develop and establish the massively parallel approach for the description of groundwater flow and transport and to address the problem of uncertainties in the data and its interpretation. This necessitated the development of innovative algorithms and the implementation of massively parallel computational tools to provide a suite of simulators for groundwater flow and transport in heterogeneous media. This report summarizes the activities and deliverables of the Groundwater Grand Challenge project funded through the High Performance Computing grand challenge program of the Department of Energy from 1995 through 1997.

  9. Grand challenge problems in environmental modeling and remediation: Groundwater contaminant transport. Final project report 1998

    International Nuclear Information System (INIS)

    The over-reaching goal of the Groundwater Grand Challenge component of the Partnership in Computational Science (PICS) was to develop and establish the massively parallel approach for the description of groundwater flow and transport and to address the problem of uncertainties in the data and its interpretation. This necessitated the development of innovative algorithms and the implementation of massively parallel computational tools to provide a suite of simulators for groundwater flow and transport in heterogeneous media. This report summarizes the activities and deliverables of the Groundwater Grand Challenge project funded through the High Performance Computing grand challenge program of the Department of Energy from 1995 through 1997

  10. A Personal Account of the Development of Stanley, the Robot That Won the DARPA Grand Challenge

    OpenAIRE

    Thrun, Sebastian

    2006-01-01

    This article is my personal account on the work at Stanford on Stanley, the winning robot in the DARPA Grand Challenge. Between July 2004 and October 2005, my then-postdoc Michael Montemerlo and I led a team of students, engineers, and professionals with the single vision of claiming one of the most prestigious trophies in the field of robotics: the DARPA Grand Challenge (DARPA 2004). The Grand Challenge, organized by the U.S. government, was unprecedented in the nation's history. It was the ...

  11. Virginia Tech's Cliff and Rocky selected for Grand Challenge starting line

    OpenAIRE

    Crumbley, Liz

    2005-01-01

    Virginia Tech's "Cliff" and "Rocky" were among an elite group of 23 autonomous vehicles that revved their engines on Oct. 8 at the starting line of the $2 million DARPA Grand Challenge race through the Mojave Desert.

  12. A BLUEPRINT FOR IMPLEMENTING GRAND CHALLENGE SCHOLARS’ PROGRAMME: A CASE STUDY OF TAYLOR’S UNIVERSITY

    Directory of Open Access Journals (Sweden)

    MUSHTAK AL-ATABI

    2013-04-01

    Full Text Available The National Academy for Engineering announced 14 Grand Challenges for the 21st Century engineers to address in order to ensure a sustainable future for the generations to come. These grand challenges are in four broad areas, namely, energy and environment, health, security and learning and computation. This paper reports on a Grand Challenges Scholars’ Programme that is developed to prepare the engineering students to be able to address the grand challenges using the CDIO framework and focusing on five components; research experience, interdisciplinary curriculum, entrepreneurship, global dimension and service learning. The programme is voluntary and the candidates are expected to commit additional learning time. The programme was launched with 16 participants who are expected to graduate in 2016. A preliminary assessment of the programs shows that the participants found the programme useful in developing an array of CDIO skills. The School intends to continue offering this programme with the intention of integrating it with a holistic education approach.

  13. Great Problems of Grand Challenges: Problematizing Engineering’s Understandings of its Role in Society

    OpenAIRE

    Erin Cech; "Guest Introduction to Special Issue on NAE's Grand Challenges for Engineering"

    2012-01-01

    The U.S. National Academy of Engineering’s Grand Challenges for Engineering report has received a great deal of attention from legislators, policymakers, and educators, but what does it entail for social justice considerations in engineering? This article situates the Grand Challenges report as a cultural artifact of the engineering profession—an artifact that works to reinforce engineering’s professional culture, recruit new members, and reassert engineering’s legitimacy in the 21st century....

  14. Addressing the Grand Challenge of atmospheric carbon dioxide: geologic sequestration vs. biological recycling

    Directory of Open Access Journals (Sweden)

    Stuart Ben J

    2011-11-01

    Full Text Available Abstract On February 15, 2008, the National Academy of Engineering unveiled their list of 14 Grand Challenges for Engineering. Building off of tremendous advancements in the past century, these challenges were selected for their role in assuring a sustainable existence for the rapidly increasing global community. It is no accident that the first five Challenges on the list involve the development of sustainable energy sources and management of environmental resources. While the focus of this review is to address the single Grand Challenge of "develop carbon sequestration methods", is will soon be clear that several other Challenges are intrinsically tied to it through the principles of sustainability. How does the realm of biological engineering play a role in addressing these Grand Challenges?

  15. A Library in the Grands Moulins de Paris: challenging Reality

    OpenAIRE

    Catherine Tresson

    2006-01-01

    In 2006, the University of Paris 7 and its new Main Library will move to Paris Rive Gauche, a recently developed neighbourhood on the left bank of the Seine. The library will occupy most of the city’s former industrial mills, the Grands Moulins de Paris. As part of the project, the library developed a very detailed functional program. The facilities are expected to comprise 1,800 workstations (half of which will be computerized), and upon completion will have a capacity of 300,000 freely acce...

  16. A Library in the Grands Moulins de Paris: challenging Reality

    Directory of Open Access Journals (Sweden)

    Catherine Tresson

    2006-07-01

    Full Text Available In 2006, the University of Paris 7 and its new Main Library will move to Paris Rive Gauche, a recently developed neighbourhood on the left bank of the Seine. The library will occupy most of the city’s former industrial mills, the Grands Moulins de Paris. As part of the project, the library developed a very detailed functional program. The facilities are expected to comprise 1,800 workstations (half of which will be computerized, and upon completion will have a capacity of 300,000 freely accessible documents and 350,000 documents in store over a total surface area of some 12,000 m2. The architect Rudy Ricciotti won the international competition to design the library held in 2001. Perfectly suited to its function, the industrial building in which the library is housed dates from the 1920s. It presents both advantages (vast surfaces, sufficient load-bearing capacity, natural light, etc. and obstacles (restrictions on free circulation, forests of columns in certain areas, interrupted spaces, etc. to being transformed into a library that is functional and adapted to its purposes. The building’s structure and the constraints it imposed profoundly influenced the program which had to be adjusted, and also affected other aspects, including the arrangement and features of the furnishings as well as the building’s system of signs. In agreement with the university, the library worked in close collaboration with the architect from the earliest sketches onwards. As a result, his initial plan also evolved considerably. The installation of the library in the Grands Moulins offers us a chance to observe the nature and effects of the interactions between the transformation of a building and the evolution of a program.

  17. KDE Bioscience: platform for bioinformatics analysis workflows.

    Science.gov (United States)

    Lu, Qiang; Hao, Pei; Curcin, Vasa; He, Weizhong; Li, Yuan-Yuan; Luo, Qing-Ming; Guo, Yi-Ke; Li, Yi-Xue

    2006-08-01

    Bioinformatics is a dynamic research area in which a large number of algorithms and programs have been developed rapidly and independently without much consideration so far of the need for standardization. The lack of such common standards combined with unfriendly interfaces make it difficult for biologists to learn how to use these tools and to translate the data formats from one to another. Consequently, the construction of an integrative bioinformatics platform to facilitate biologists' research is an urgent and challenging task. KDE Bioscience is a java-based software platform that collects a variety of bioinformatics tools and provides a workflow mechanism to integrate them. Nucleotide and protein sequences from local flat files, web sites, and relational databases can be entered, annotated, and aligned. Several home-made or 3rd-party viewers are built-in to provide visualization of annotations or alignments. KDE Bioscience can also be deployed in client-server mode where simultaneous execution of the same workflow is supported for multiple users. Moreover, workflows can be published as web pages that can be executed from a web browser. The power of KDE Bioscience comes from the integrated algorithms and data sources. With its generic workflow mechanism other novel calculations and simulations can be integrated to augment the current sequence analysis functions. Because of this flexible and extensible architecture, KDE Bioscience makes an ideal integrated informatics environment for future bioinformatics or systems biology research. PMID:16260186

  18. The grand challenges of plasma etching: a manufacturing perspective

    International Nuclear Information System (INIS)

    Plasma etching has been enabling nano-electronic fabrication since the 1980s; during this time, transistor size has shrunk by nearly two orders of magnitude, starting at 1.0 µm in the mid 80s to ∼0.01 µm today. The manufacturing of these devices requires overcoming a series of challenges, ranging from continuous innovation on device integration to extend Moore's law to breaking tradeoffs on the perennial challenge of aspect ratio-dependent etching. In this paper, we will review four key areas in etch manufacturing: uniformity, defects, surface precision and ‘sticky’/non-volatile etch materials. In the uniformity section, we will discuss the challenges for microscopic uniformity, such as localized feature dimension variations; macroscopic uniformity, such as performance at the extreme edge of the wafer; and repeatable uniformity, meaning wafer-to-wafer, lot-to-lot and chamber-to-chamber performance. While defect management is successful with in situ plasma cleans, one must be cognizant of the choice of clean chemistry. In surface precision, we look at the approach of atomic layer etching and how it can be successful in a manufacturing environment. Finally, in the non-volatile material section, we review technology drivers for DRAM (dynamic random access memory) and NAND flash memory in the microelectronics Si industry, with focus on the utilization of such materials and what it means to etch equipment manufacturers. (topical review)

  19. Tracking Student Participants from a REU Site with NAE Grand Challenges as the Common Theme

    Science.gov (United States)

    Burkett, Susan; Dye, Tabatha; Johnson, Pauline

    2015-01-01

    The National Academy of Engineering (NAE) Grand Challenges provides the theme for this NSFfunded Research Experience for Undergraduates (REU) site. Research topics, with their broad societal impact, allow undergraduate students from multiple engineering disciplines and computer science to work together on exciting and critical problems. The…

  20. Promoting Collaborative Problem-Solving Skills in a Course on Engineering Grand Challenges

    Science.gov (United States)

    Zou, Tracy X. P.; Mickleborough, Neil C.

    2015-01-01

    The ability to solve problems with people of diverse backgrounds is essential for engineering graduates. A course on engineering grand challenges was designed to promote collaborative problem-solving (CPS) skills. One unique component is that students need to work both within their own team and collaborate with the other team to tackle engineering…

  1. Grand challenge problems in environmental modeling and remediation: groundwater contaminant transport

    Energy Technology Data Exchange (ETDEWEB)

    Todd Arbogast; Steve Bryant; Clint N. Dawson; Mary F. Wheeler

    1998-08-31

    This report describes briefly the work of the Center for Subsurface Modeling (CSM) of the University of Texas at Austin (and Rice University prior to September 1995) on the Partnership in Computational Sciences Consortium (PICS) project entitled Grand Challenge Problems in Environmental Modeling and Remediation: Groundwater Contaminant Transport.

  2. Virginia Tech qualifies two vehicles for $2 million DARPA Grand Challenge race

    OpenAIRE

    Crumbley, Liz

    2005-01-01

    Two Virginia Tech engineering teams are among only 40 in the nation to qualify for the 2005 DARPA Grand Challenge autonomous vehicle competition, which offers a cash prize of $2 million. In addition, Virginia Tech is one of only two competitors to qualify two vehicles -- "Rocky" and "Cliff" -- for the race across the Mojave Desert on Oct. 8.

  3. Using Grand Challenges For Innovative Teaching in Structural Geology, Geophysics, and Tectonics

    Science.gov (United States)

    McDaris, J. R.; Tewksbury, B. J.; Wysession, M. E.

    2012-12-01

    An innovative approach to teaching involves using the "Big Ideas" or "Grand Challenges" of a field, as determined by the research community in that area, as the basis for classroom activities. There have been several recent efforts in the areas of structural geology, tectonics, and geophysics to determine these Grand Challenges, including the areas of seismology ("Seismological Grand Challenges in Understanding Earth's Dynamic Systems"), mineral physics ("Unlocking the Building Blocks of the Planet"), EarthScope-related science ("Unlocking the Secrets of the North American Continent: An EarthScope Science Plan for 2010-2020"), and structural geology and tectonics (at the Structural Geology and Tectonics Forum held at Williams College in June, 2012). These research community efforts produced frameworks of the essential information for their fields with the aim of guiding future research. An integral part of this, however, is training the next generation of scientists, and using these Big Ideas as the basis for course structures and activities is a powerful way to make this happen. When activities, labs, and homeworks are drawn from relevant and cutting-edge research topics, students can find the material more fascinating and engaging, and can develop a better sense of the dynamic process of scientific discovery. Many creative ideas for incorporating the Grand Challenges of structural geology, tectonics, and geophysics in the classroom were developed at a Cutting Edge workshop on "Teaching Structural Geology, Geophysics, and Tectonics in the 21st Century" held at the University of Tennessee in July, 2012.

  4. Biofuels and Sustainable Development: An Executive Session on the Grand Challenges of the Sustainability Transition

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Henry [Harvard Univ., Cambridge, MA (United States); Clark, William C. [Harvard Univ., Cambridge, MA (United States); Devereaux, Charan [Harvard Univ., Cambridge, MA (United States)

    2008-05-20

    This report is the result of the second in a series of intense workshops and study sessions on Grand Challenges of the Sustainability Transition, organized by the Sustainability Science Program at Harvard University, hosted by Venice International University, and supported by the Italian Ministry of Environment, Land and Sea.

  5. Grand Challenges and Chemical Engineering Curriculum--Developments at TU Dortmund University

    Science.gov (United States)

    Kockmann, Norbert; Lutze, Philip; Gorak, Andrzej

    2016-01-01

    Chemical processing industry is progressively focusing their research activities and product placements in the areas of Grand Challenges (or Global Megatrends) such as mobility, energy, communication, or health care and food. Innovation in all these fields requires solving high complex problems, rapid product development as well as dealing with…

  6. Underwater Visual Computing: The Grand Challenge Just around the Corner.

    Science.gov (United States)

    von Lukas, Uwe Freiherr

    2016-01-01

    Visual computing technologies have traditionally been developed for conventional setups where air is the surrounding medium for the user, the display, and/or the camera. However, given mankind's increasingly need to rely on the oceans to solve the problems of future generations (such as offshore oil and gas, renewable energies, and marine mineral resources), there is a growing need for mixed-reality applications for use in water. This article highlights the various research challenges when changing the medium from air to water, introduces the concept of underwater mixed environments, and presents recent developments in underwater visual computing applications. PMID:26960024

  7. Using Grand Challenges to Teach Science: A Biology-Geology Collaboration

    Science.gov (United States)

    Lyford, M.; Myers, J. D.

    2012-12-01

    Three science courses at the University of Wyoming explore the inextricable connections between science and society by centering on grand challenges. Two of these courses are introductory integrated science courses for non-majors while the third is an upper level course for majors and non-majors. Through collaboration, the authors have developed these courses to explore the grand challenges of energy, water and climate. Each course focuses on the fundamental STEM principles required for a citizen to understand each grand challenge. However, the courses also emphasize the non-STEM perspectives (e.g., economics, politics, human well-being, externalities) that underlie each grand challenge and argue that creating equitable, sustainable and just solutions to the grand challenges hinges on an understanding of STEM and non-STEM perspectives. Moreover, the authors also consider the multitude of personal perspectives individuals bring to the classroom (e.g., values, beliefs, empathy misconceptions) that influence any stakeholder's ability to engage in fruitful discussions about grand challenge solutions. Discovering Science (LIFE 1002) focuses on the grand challenges of energy and climate. Students attend three one-hour lectures, one two-hour lab and a one-hour discussion each week. Lectures emphasize the STEM and non-STEM principles underlying each grand challenge. Laboratory activities are designed to be interdisciplinary and engage students in inquiry-driven activities to reinforce concepts from lecture and to model how science is conducted. Labs also expose students to the difficulties often associated with scientific studies, the limits of science, and the inherent uncertainties associated with scientific findings. Discussion sessions provide an opportunity for students to explore the complexity of the grand challenges from STEM and non-STEM perspectives, and expose the multitude of personal perspectives an individual might harbor related to each grand challenge

  8. Challenges and opportunities for early-career Teaching-Focussed academics in the biosciences [v2; ref status: indexed, http://f1000r.es/5c2

    Directory of Open Access Journals (Sweden)

    Katharine Hubbard

    2015-04-01

    Full Text Available Twenty-seven percent of academics in UK Higher Education (HE are in Teaching-Focussed positions, making major contributions to undergraduate programmes in an era of high student expectations when it comes to teaching quality. However, institutional support for Teaching-Focussed academics is often limited, both in terms of peer networking and opportunities for career development. As four early-career stage Teaching-Focussed academics working in a variety of institutions, we explore what motivated our choices to make teaching our primary academic activity, and the challenges that we have faced in doing so. In addition to highlighting the need for universities to fully recognise the achievements of teaching staff, we discuss the role that the various biosciences learned societies have in supporting Teaching-Focussed academics. We identify that there is a need for the learned societies to come together and pool their expertise in this area. The fragmented nature of the Teaching-Focussed academic community means that clear sources of national support are needed in order to best enable the next generation of bioscience educators to reach their full potential.

  9. Building a Course on Global Sustainability using the grand challenges of Energy-Water-Climate

    Science.gov (United States)

    Myers, J. D.

    2012-12-01

    GEOL1600: Global Sustainability: Managing the Earth's Resources is a lower division integrated science course at the University of Wyoming that fulfills the university's science requirement. Course content and context has been developed using the grand challenge nexus of energy-water-and climate (EWC). The interconnection of these issues, their social relevance and timeliness has provided a framework that gives students an opportunity to recognize why STEM is relevant to their lives regardless of their ultimate professional career choices. The EWC nexus provides the filter to sieve the course's STEM content. It also provides an ideal mechanism by which the non-STEM perspectives important in grand challenge solutions can be seamlessly incorporated in the course. Through a combination of content and context, the relevance of these issues engage students in their own learning. Development of the course followed the Grand Challenge Scientific Literacy (GCSL) model independently developed by the author and two colleagues at the University of Wyoming. This course model stresses science principles centered on the nature of science (e.g., fundamental premises, habits of mind, critical thinking) and unifying scientific concepts (e.g., methods and tools, experimentation, modeling). Grand challenge principles identify the STEM and non-STEM concepts needed to understand the grand challenges, drawing on multiple STEM and non-STEM disciplines and subjects (i.e., economics, politics, unintended consequences, roles of stakeholders). Using the EWC nexus filter and building on the Grand Challenge Principles, specific content included in the course is selected is that most relevant to understanding the Grand Challenges, thereby stressing content depth over breadth. Because quantitative data and reasoning is critical to effectively evaluating challenge solutions, QR is a component of nearly all class activities, while engineering and technology aspects of grand challenges are

  10. The grand challenge of managing the petascale facility.

    Energy Technology Data Exchange (ETDEWEB)

    Aiken, R. J.; Mathematics and Computer Science

    2007-02-28

    This report is the result of a study of networks and how they may need to evolve to support petascale leadership computing and science. As Dr. Ray Orbach, director of the Department of Energy's Office of Science, says in the spring 2006 issue of SciDAC Review, 'One remarkable example of growth in unexpected directions has been in high-end computation'. In the same article Dr. Michael Strayer states, 'Moore's law suggests that before the end of the next cycle of SciDAC, we shall see petaflop computers'. Given the Office of Science's strong leadership and support for petascale computing and facilities, we should expect to see petaflop computers in operation in support of science before the end of the decade, and DOE/SC Advanced Scientific Computing Research programs are focused on making this a reality. This study took its lead from this strong focus on petascale computing and the networks required to support such facilities, but it grew to include almost all aspects of the DOE/SC petascale computational and experimental science facilities, all of which will face daunting challenges in managing and analyzing the voluminous amounts of data expected. In addition, trends indicate the increased coupling of unique experimental facilities with computational facilities, along with the integration of multidisciplinary datasets and high-end computing with data-intensive computing; and we can expect these trends to continue at the petascale level and beyond. Coupled with recent technology trends, they clearly indicate the need for including capability petascale storage, networks, and experiments, as well as collaboration tools and programming environments, as integral components of the Office of Science's petascale capability metafacility. The objective of this report is to recommend a new cross-cutting program to support the management of petascale science and infrastructure. The appendices of the report document current and projected

  11. Avoiding collapse: Grand challenges for science and society to solve by 2050

    OpenAIRE

    Barnosky, Anthony D.; Ehrlich, Paul R.; Hadly, Elizabeth A.

    2016-01-01

    Abstract We maintain that humanity’s grand challenge is solving the intertwined problems of human population growth and overconsumption, climate change, pollution, ecosystem destruction, disease spillovers, and extinction, in order to avoid environmental tipping points that would make human life more difficult and would irrevocably damage planetary life support systems. These are not future issues: for example, detrimental impacts of climate change (increased wildfires and extreme weather, se...

  12. The Unbalanced Equation: Technical Opportunities and Social Barriers in the NAE Grand Challenges and Beyond

    OpenAIRE

    Dean Nieusma; Xiaofeng Tang

    2012-01-01

    The US National Academy of Engineering’s 2008 report, Grand Challenges for Engineering, puts forward a provocative vision of future civilization and engineering’s role in it. Notably, the report signals a trend in engineering toward more explicit and direct engagement with enduring, complex social problems, offering intriguing opportunities for exploring the relationship between engineering and questions of social justice. This paper makes one such exploration by analyzing the report’s explic...

  13. Listening to the Quiet Voices: Unlocking the Heart of Engineering Grand Challenges

    OpenAIRE

    George D Catalano

    2012-01-01

    According to the National Academy of Engineering, the list for the Grand Challenges for Engineering are: (1) Make solar energy economical; (2) Provide energy from fusion; (3) Develop carbon sequestration methods; (4) Manage the nitrogen cycle; (5) Provide access to clean water; (6) Restore and improve urban infrastructure; (7) Advance health informatics; (8) Engineer better medicines; (9) Reverse-engineer the brain; (10) Prevent nuclear terror; (11) Secure cyberspace; (12) Enhance virtual rea...

  14. How to teach a van to drive: an undergraduate perspective on the 2005 DARPA Grand Challenge

    OpenAIRE

    Gillula, Jeremy; Leibs, Jeremy

    2006-01-01

    This paper describes how a team of undergraduate volunteers from California Institute of Technology (Caltech) developed a robotic vehicle that can navigate completely autonomously through the Mojave Desert. Called Alice, the vehicle was Caltech's entry to the 2005 DARPA Grand Challenge which aimed to generate the technology needed to build and program an unmanned ground vehicle through 130 miles of difficult terrain completely autonomously in under ten hours. Although Alice failed to win the ...

  15. A Grand Challenge: Immortal Information and Through-Life Knowledge Management (KIM)

    OpenAIRE

    Alexander Ball; Manjula Patel; Chris McMahon; Stuart Green; John Clarkson; Steve Culley

    2006-01-01

    ‘Immortal information and through-life knowledge management: strategies and tools for the emerging product-service business paradigm’, is a Grand Challenge project involving eleven different UK universities and incorporating substantial industry collaboration. It is investigating a range of issues associated with the move towards a product-service paradigm in the engineering sector, in particular the long-term curation of digital data, learning from production and use, and appropriate governa...

  16. A Grand Challenge: Immortal Information and Through-Life Knowledge Management (KIM

    Directory of Open Access Journals (Sweden)

    Alexander Ball

    2006-11-01

    Full Text Available ‘Immortal information and through-life knowledge management: strategies and tools for the emerging product-service business paradigm’, is a Grand Challenge project involving eleven different UK universities and incorporating substantial industry collaboration. It is investigating a range of issues associated with the move towards a product-service paradigm in the engineering sector, in particular the long-term curation of digital data, learning from production and use, and appropriate governance and management techniques.

  17. Environmental Biosciences Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2007-01-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the DOE. Plans for restructuring the performance schedule of the trichloroethylene projects have been submitted to the department. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this

  18. Professor Jin Yuan in ZOC Won the "Grand Challenge 2015 Young Scientist" Award.

    Science.gov (United States)

    Seliman, Helen X

    2015-12-01

    Professor Yuan Jin from Zhongshan Ophthalmic Center (ZOC) affiliated with Sun Yat-sen University has recently won the "Grand Challenge 2015 Young Scientist" award in "2015 Innovation Challenge Annual Meeting" held in Beijing. The meeting is organized by the Ministry of Science and Technology of the People Republic of China (MOST), the Bill & Melinda Gates Foundation in the United States and the US Agency for International Development. The journal Eye Science (ES) is the official publication of ZOC, sponsored by Sun Yat-sen University. PMID:27214997

  19. The MICE Grand Challenge lightcone simulation - II. Halo and galaxy catalogues

    Science.gov (United States)

    Crocce, M.; Castander, F. J.; Gaztañaga, E.; Fosalba, P.; Carretero, J.

    2015-10-01

    This is the second in a series of three papers in which we present an end-to-end simulation from the MICE collaboration, the MICE Grand Challenge (MICE-GC) run. The N-body contains about 70 billion dark-matter particles in a (3 h-1 Gpc)3 comoving volume spanning five orders of magnitude in dynamical range. Here, we introduce the halo and galaxy catalogues built upon it, both in a wide (5000 deg2) and deep (z MICECATv1.0) publicly available through a dedicated web portal to help develop and exploit the new generation of astronomical surveys.

  20. Avoiding collapse: Grand challenges for science and society to solve by 2050

    Directory of Open Access Journals (Sweden)

    Anthony D. Barnosky

    2016-03-01

    Full Text Available Abstract We maintain that humanity’s grand challenge is solving the intertwined problems of human population growth and overconsumption, climate change, pollution, ecosystem destruction, disease spillovers, and extinction, in order to avoid environmental tipping points that would make human life more difficult and would irrevocably damage planetary life support systems. These are not future issues: for example, detrimental impacts of climate change (increased wildfires and extreme weather, sea-level rise, ocean acidification, pollution (contaminated drinking water in many parts of the world, rapid population growth in some areas (contributing to poverty, war, and increasingly frequent migration and overconsumption in others (a main driver of overexploitation of resources and greenhouse gas emissions, and new disease outbreaks (Ebola, Zika virus already are apparent today, and if trends of the past half century continue, even more damaging, long-lasting impacts would be locked in within three decades. Solving these problems will require some scientific and technological breakthroughs, but that will not be enough. Even more critical will be effective collaboration of environmental and physical scientists with social scientists and those in the humanities, active exchange of information among practitioners in academics, politics, religion, and business and other stakeholders, and clear communication of relevant issues and solutions to the general public. This special feature offers examples of how researchers are addressing this grand challenge through the process of discovering new knowledge and relevant tools, transferring insights across disciplinary boundaries, and establishing critical dialogues with those outside academia to help effect positive global change.

  1. Scientific Grand Challenges: Crosscutting Technologies for Computing at the Exascale - February 2-4, 2010, Washington, D.C.

    Energy Technology Data Exchange (ETDEWEB)

    Khaleel, Mohammad A.

    2011-02-06

    The goal of the "Scientific Grand Challenges - Crosscutting Technologies for Computing at the Exascale" workshop in February 2010, jointly sponsored by the U.S. Department of Energy’s Office of Advanced Scientific Computing Research and the National Nuclear Security Administration, was to identify the elements of a research and development agenda that will address these challenges and create a comprehensive exascale computing environment. This exascale computing environment will enable the science applications identified in the eight previously held Scientific Grand Challenges Workshop Series.

  2. Grand Challenges for Biological and Environmental Research: A Long-Term Vision

    Energy Technology Data Exchange (ETDEWEB)

    Arkin, A.; Baliga, N.; Braam, J.; Church, G.; Collins, J; ; Cottingham, R.; Ecker, J.; Gerstein, M.; Gilna, P.; Greenberg, J.; Handelsman, J.; Hubbard, S.; Joachimiak, A.; Liao, J.; Looger, L.; Meyerowitz, E.; Mjolness, E.; Petsko, G.; Sayler, G.; Simpson, M.; Stacey, G.; Sussman, M.; Tiedje, J.; Bader, D.; Cessi, P.; Collins, W.; Denning, S.; Dickinson, R.; Easterling, D.; Edmonds, J.; Feddema, J.; Field, C.; Fridlind, A.; Fung, I.; Held, I.; Jackson, R.; Janetos, A.; Large, W.; Leinen, M.; Leung, R.; Long, S.; Mace, G.; Masiello, C.; Meehl, G.; Ort, D.; Otto-Bliesner, B.; Penner, J.; Prather, M.; Randall, D.; Rasch, P.; Schneider, E.; Shugart, H.; Thornton, P.; Washington, W.; Wildung, R.; Wiscombe, W.; Zak, D.; Zhang, M.; Bielicki, J.; Buford, M.; Cleland, E.; Dale, V.; Duke, C.; Ehleringer, J.; Hecht, A.; Kammen, D.; Marland, G.; Pataki, D.; Riley, M. Robertson, P.; Hubbard, S.

    2010-12-01

    outcomes and behaviors of complex biological and environmental systems, leading to robust solutions for DOE missions and strategic goals. In March 2010, the Biological and Environmental Research Advisory Committee held the Grand Challenges for Biological and Environmental Research: A Long-Term Vision workshop to identify scientific opportunities and grand challenges for BER science in the coming decades and to develop an overall strategy for drafting a long-term vision for BER. Key workshop goals included: (1) Identifying the greatest scientific challenges in biology, climate, and the environment that DOE will face over a 20-year time horizon. (2) Describing how BER should be positioned to address those challenges. (3) Determining the new and innovative tools needed to advance BER science. (4) Suggesting how the workforce of the future should be trained in integrative system science. This report lays out grand research challenges for BER - in biological systems, climate, energy sustainability, computing, and education and workforce training - that can put society on a path to achieve the scientific evidence and predictive understanding needed to inform decision making and planning to address future energy needs, climate change, water availability, and land use.

  3. Network discovery, characterization, and prediction : a grand challenge LDRD final report.

    Energy Technology Data Exchange (ETDEWEB)

    Kegelmeyer, W. Philip, Jr.

    2010-11-01

    This report is the final summation of Sandia's Grand Challenge LDRD project No.119351, 'Network Discovery, Characterization and Prediction' (the 'NGC') which ran from FY08 to FY10. The aim of the NGC, in a nutshell, was to research, develop, and evaluate relevant analysis capabilities that address adversarial networks. Unlike some Grand Challenge efforts, that ambition created cultural subgoals, as well as technical and programmatic ones, as the insistence on 'relevancy' required that the Sandia informatics research communities and the analyst user communities come to appreciate each others needs and capabilities in a very deep and concrete way. The NGC generated a number of technical, programmatic, and cultural advances, detailed in this report. There were new algorithmic insights and research that resulted in fifty-three refereed publications and presentations; this report concludes with an abstract-annotated bibliography pointing to them all. The NGC generated three substantial prototypes that not only achieved their intended goals of testing our algorithmic integration, but which also served as vehicles for customer education and program development. The NGC, as intended, has catalyzed future work in this domain; by the end it had already brought in, in new funding, as much funding as had been invested in it. Finally, the NGC knit together previously disparate research staff and user expertise in a fashion that not only addressed our immediate research goals, but which promises to have created an enduring cultural legacy of mutual understanding, in service of Sandia's national security responsibilities in cybersecurity and counter proliferation.

  4. New capabilities in the HENP grand challenge storage access system and its application at RHIC

    International Nuclear Information System (INIS)

    The High Energy and Nuclear Physics Data Access Grand Challenge project has developed an optimizing storage access software system that was prototyped at RHIC. It is currently undergoing integration with the STAR experiment in preparation for data taking that starts in mid-2000. The behavior and lessons learned in the RHIC Mock Data Challenge exercises are described as well as the observed performance under conditions designed to characterize scalability. Up to 250 simultaneous queries were tested and up to 10 million events across 7 event components were involved in these queries. The system coordinates the staging of ''bundles'' of files from the HPSS tape system, so that all the needed components of each event are in disk cache when accessed by the application software. The caching policy algorithm for the coordinated bundle staging is described in the paper. The initial prototype implementation interfaced to the Objectivity/DB. In this latest version, it evolved to work with arbitrary files and use CORBA interfaces to the tag database and file catalog services. The interface to the tag database and the MySQL-based file catalog services used by STAR are described along with the planned usage scenarios

  5. Addressing China's grand challenge of achieving food security while ensuring environmental sustainability.

    Science.gov (United States)

    Lu, Yonglong; Jenkins, Alan; Ferrier, Robert C; Bailey, Mark; Gordon, Iain J; Song, Shuai; Huang, Jikun; Jia, Shaofeng; Zhang, Fusuo; Liu, Xuejun; Feng, Zhaozhong; Zhang, Zhibin

    2015-02-01

    China's increasingly urbanized and wealthy population is driving a growing and changing demand for food, which might not be met without significant increase in agricultural productivity and sustainable use of natural resources. Given the past relationship between lack of access to affordable food and political instability, food security has to be given a high priority on national political agendas in the context of globalization. The drive for increased food production has had a significant impact on the environment, and the deterioration in ecosystem quality due to historic and current levels of pollution will potentially compromise the food production system in China. We discuss the grand challenges of not only producing more food but also producing it sustainably and without environmental degradation. In addressing these challenges, food production should be considered as part of an environmental system (soil, air, water, and biodiversity) and not independent from it. It is imperative that new ways of meeting the demand for food are developed while safeguarding the natural resources upon which food production is based. We present a holistic approach to both science and policy to ensure future food security while embracing the ambition of achieving environmental sustainability in China. It is a unique opportunity for China to be a role model as a new global player, especially for other emerging economies. PMID:26601127

  6. Cliff and Rocky may not have won the Grand Challenge, but they out-performed peer competitors

    OpenAIRE

    Crumbley, Liz

    2005-01-01

    The official results of the DARPA Grand Challenge autonomous vehicle race through the Mojave Desert are in and, although the two Virginia Tech vehicles did not win the $2 million prize or even complete the 132-mile course, they out-performed all other vehicles developed by purely academic teams.

  7. Groundwater Challenges of the Lower Rio Grande: A Case Study of Legal Issues in Texas and New Mexico

    Directory of Open Access Journals (Sweden)

    Elizabeth Wheat

    2015-03-01

    Full Text Available In 1938, Texas, New Mexico, and Colorado signed the Rio Grande Compact, establishing terms of apportionment for some of the water from the Rio Grande for the three states. Following congressional approval in 1939, this compact governs water allocation in a region with a variable climate and frequent drought conditions and established the Rio Grande Compact Commission, comprised of a commissioner from each state and one from the federal government, to enforce the compact. With an increasing population and declining surface water supply, the Compact has been tested among the parties and within the states themselves. In a case currently before the U.S. Supreme Court, Texas v. New Mexico and Colorado (2013, Texas claims New Mexico is violating the Compact and Rio Grande Project Act by using water in excess of its apportionment through its allowance of diversions of surface and groundwater. The issue is further compounded by disputes within Texas over separate legal regimes for groundwater and surface water. Combined with growing scarcity issues, the allocation of water in the Lower Rio Grande presents a timely natural resource challenge. This review explores legal issues involved in the case as well as growing challenges of population growth, agricultural development needs, and water shortages.

  8. Intersections of downscaling, the ethics of climate services, and regional research grand challenges.

    Science.gov (United States)

    Hewitson, B.; Jack, C. D.; Gutowski, W. J., Jr.

    2014-12-01

    Possibly the leading complication for users of climate information for policy and adaptation is the confusing mix of contrasting data sets that offer widely differing (and often times fundamentally contradictory) indications of the magnitude and direction of past and future regional climate change. In this light, the most pressing scientific-societal challenge is the need to find new ways to understand the sources of conflicting messages from multi-model, multi-method and multi-scale disparities, to develop and implement new analytical methodologies to address this difficulty and so to advance the interpretation and communication of robust climate information to decision makers. Compounding this challenge is the growth of climate services which, in view of the confusing mix of climate change messages, raises serious concerns as to the ethics of communication and dissemination of regional climate change data.The Working Group on Regional Climate (WGRC) of the World Climate Research Program (WCRP) oversees the CORDEX downscaling program which offers a systematic approach to compare the CMIP5 GCMs alongside RCMs and Empirical-statistical (ESD) downscaling within a common experimental design, and which facilitates the evaluation and assessment of the relative information content and sources of error. Using results from the CORDEX RCM and ESD evaluation experiment, and set against the regional messages from the CMIP5 GCMs, we examine the differing messages that arise from each data source. These are then considered in terms of the implications of consequence if each data source were to be independently adopted in a real world use-case scenario. This is then cast in the context of the emerging developments on the distillation dilemma - where the pressing need is for multi-method integration - and how this relates to the WCRP regional research grand challenges.

  9. The MICE Grand Challenge Lightcone Simulation II: Halo and Galaxy catalogues

    CERN Document Server

    Crocce, M; Gaztanaga, E; Fosalba, P; Carretero, J

    2013-01-01

    This is the second in a series of three papers in which we present an end-to-end simulation from the MICE collaboration, the MICE Grand Challenge (MICE-GC) run. The N-body contains about 70 billion dark-matter particles in a (3 \\Gpc)^3 comoving volume spanning 5 orders of magnitude in dynamical range. In this paper we introduce the halo and galaxy catalogues built upon it, both in a wide (5000 sq. deg) and deep (z<1.4) light-cone and in several redshift snapshots. Friend-of-friends halos were resolved down to few 10^{11} Msun/h what allowed us to model galaxies down to faint luminosities (absolute magnitudes M_r<-18.9). We used a new hybrid Halo Occupation Distribution and Abundance Matching technique for galaxy assignment. The catalogue includes the Spectral Energy Distributions of all galaxies from which we can model multi-band photometric galaxy surveys. We describe a variety of applications for halo and galaxy clustering statistics. We discuss how mass resolution effects can bias the large scale 2-p...

  10. A Grand Challenge: Unbiased Phenotypic Function of Metabolites from Jaspis splendens against Parkinson's Disease.

    Science.gov (United States)

    Wang, Dongdong; Feng, Yunjiang; Murtaza, Mariyam; Wood, Stephen; Mellick, George; Hooper, John N A; Quinn, Ronald J

    2016-02-26

    A grand challenge in natural product chemistry is to determine the biological effects of all natural products. A phenotypic approach is frequently used for determining the activity of a compound and its potential impact on a disease state. Chemical investigation of a specimen of Jaspis splendens collected from the Great Barrier Reef resulted in the isolation of a new pterin derivative, jaspterin (1), a new bisindole alkaloid, splendamide (2), and a new imidazole alkaloid, jaspnin A (3) TFA salt. Jaspamycin (8) and 6-bromo-1H-indole-3-carboximidamide (16) are reported for the first time as naturally occurring metabolites. Known nucleosides (4-7, 9, 10), aglycones (11-13), indole alkaloids (14, 15, 17), and jaspamide peptides (18-22) were also isolated. The structures of the three new compounds 1-3 were unambiguously elucidated based on NMR and mass spectroscopic data. Jaspnin A (3) contained a rare thiomethylated imidazolinium unit. Coupling an unbiased phenotypic assay using a human olfactory neurosphere-derived cell model of Parkinson's disease to all of the natural products from the species J. splendens allowed the phenotypic profiles of the metabolites to be investigated. PMID:26883470

  11. The MICE Grand Challenge Lightcone Simulation III: Galaxy lensing mocks from all-sky lensing maps

    CERN Document Server

    Fosalba, P; Castander, F J; Crocce, M

    2013-01-01

    In paper I of this series (Fosalba et al. 2013), we presented a new N-body lightcone simulation from the MICE collaboration, the MICE Grand Challenge (MICE-GC), containing about 70 billion dark-matter particles in a (3 Gpc)^3 comoving volume, from which we built halo and galaxy catalogues using a Halo Occupation Distribution and Halo Abundance Matching technique, as presented in the companion Paper II (Crocce et al. 2013). Given its large volume and fine mass resolution, the MICE-GC simulation also allows an accurate modeling of the lensing observables from upcoming wide and deep galaxy surveys. In the last paper of this series (Paper III), we describe the construction of all-sky lensing maps, following the "Onion Universe" approach (Fosalba et al. 2008), and discuss their properties in the lightcone up to z=1.4 with sub-arcmin spatial resolution. By comparing the convergence power spectrum in the MICE-GC to lower mass-resolution (i.e., particle mass ~ 10^11 Msun) simulations, we find that resolution effects ...

  12. Hyperresolution global land surface modeling: Meeting a grand challenge for monitoring Earth's terrestrial water

    Science.gov (United States)

    Wood, Eric F.; Roundy, Joshua K.; Troy, Tara J.; van Beek, L. P. H.; Bierkens, Marc F. P.; Blyth, Eleanor; de Roo, Ad; DöLl, Petra; Ek, Mike; Famiglietti, James; Gochis, David; van de Giesen, Nick; Houser, Paul; Jaffé, Peter R.; Kollet, Stefan; Lehner, Bernhard; Lettenmaier, Dennis P.; Peters-Lidard, Christa; Sivapalan, Murugesu; Sheffield, Justin; Wade, Andrew; Whitehead, Paul

    2011-05-01

    Monitoring Earth's terrestrial water conditions is critically important to many hydrological applications such as global food production; assessing water resources sustainability; and flood, drought, and climate change prediction. These needs have motivated the development of pilot monitoring and prediction systems for terrestrial hydrologic and vegetative states, but to date only at the rather coarse spatial resolutions (˜10-100 km) over continental to global domains. Adequately addressing critical water cycle science questions and applications requires systems that are implemented globally at much higher resolutions, on the order of 1 km, resolutions referred to as hyperresolution in the context of global land surface models. This opinion paper sets forth the needs and benefits for a system that would monitor and predict the Earth's terrestrial water, energy, and biogeochemical cycles. We discuss six major challenges in developing a system: improved representation of surface-subsurface interactions due to fine-scale topography and vegetation; improved representation of land-atmospheric interactions and resulting spatial information on soil moisture and evapotranspiration; inclusion of water quality as part of the biogeochemical cycle; representation of human impacts from water management; utilizing massively parallel computer systems and recent computational advances in solving hyperresolution models that will have up to 109 unknowns; and developing the required in situ and remote sensing global data sets. We deem the development of a global hyperresolution model for monitoring the terrestrial water, energy, and biogeochemical cycles a "grand challenge" to the community, and we call upon the international hydrologic community and the hydrological science support infrastructure to endorse the effort.

  13. Hyperresolution Global Land Surface Modeling: Meeting a Grand Challenge for Monitoring Earth's Terrestrial Water

    Science.gov (United States)

    Wood, Eric F.; Roundy, Joshua K.; Troy, Tara J.; van Beek, L. P. H.; Bierkens, Marc F. P.; 4 Blyth, Eleanor; de Roo, Ad; Doell. Petra; Ek, Mike; Famiglietti, James; Gochis, David; van de Giesen, Nick; Houser, Paul; Jaffe, Peter R.; Kollet, Stefan; Lehner, Bernhard; Lettenmaier, Dennis P.; Peters-Lidard, Christa; Sivpalan, Murugesu; Sheffield, Justin; Wade, Andrew; Whitehead, Paul

    2011-01-01

    Monitoring Earth's terrestrial water conditions is critically important to many hydrological applications such as global food production; assessing water resources sustainability; and flood, drought, and climate change prediction. These needs have motivated the development of pilot monitoring and prediction systems for terrestrial hydrologic and vegetative states, but to date only at the rather coarse spatial resolutions (approx.10-100 km) over continental to global domains. Adequately addressing critical water cycle science questions and applications requires systems that are implemented globally at much higher resolutions, on the order of 1 km, resolutions referred to as hyperresolution in the context of global land surface models. This opinion paper sets forth the needs and benefits for a system that would monitor and predict the Earth's terrestrial water, energy, and biogeochemical cycles. We discuss six major challenges in developing a system: improved representation of surface-subsurface interactions due to fine-scale topography and vegetation; improved representation of land-atmospheric interactions and resulting spatial information on soil moisture and evapotranspiration; inclusion of water quality as part of the biogeochemical cycle; representation of human impacts from water management; utilizing massively parallel computer systems and recent computational advances in solving hyperresolution models that will have up to 10(exp 9) unknowns; and developing the required in situ and remote sensing global data sets. We deem the development of a global hyperresolution model for monitoring the terrestrial water, energy, and biogeochemical cycles a grand challenge to the community, and we call upon the international hydrologic community and the hydrological science support infrastructure to endorse the effort.

  14. Listening to the Quiet Voices: Unlocking the Heart of Engineering Grand Challenges

    Directory of Open Access Journals (Sweden)

    George D Catalano

    2012-11-01

    Full Text Available According to the National Academy of Engineering, the list for the Grand Challenges for Engineering are: (1 Make solar energy economical; (2 Provide energy from fusion; (3 Develop carbon sequestration methods; (4 Manage the nitrogen cycle; (5 Provide access to clean water; (6 Restore and improve urban infrastructure; (7 Advance health informatics; (8 Engineer better medicines; (9 Reverse-engineer the brain; (10 Prevent nuclear terror; (11 Secure cyberspace; (12 Enhance virtual reality; (13 Advance personalized learning; and (14 Engineer the tools of scientific discovery. Surely, it may be difficult to find many who would find any reason to disagree with the identification of any of these topics for both the present and future engineers. Rather than object to what is included, I would like to raise the issue of what has been neglected in this list and far too often in engineering—listening to the quiet voices that speak from within each of us from our heart. I am suggesting the act of listening as one additional entry for this most important list.In my view, one set of skills that our profession does not encourage very well is stopping and listening—stopping and listening to each other, stopping and listening to life around us, or stopping and listening even to ourselves. This is a skill that, given the pace of our modern society, technological advances and our cultural conditioning, must be cultivated for it likely will simply either never develop or quickly wither away. The question at hand then becomes how does one cultivate the ability to stop and to listen? The present work offers one such path though clearly there are countless others.

  15. Storm-time Large-Scale Birkeland Currents: Salient Dynamics in Grand Challenge Events

    Science.gov (United States)

    Korth, H.; Anderson, B. J.; Waters, C. L.; Barnes, R. J.

    2015-12-01

    The Active Magnetosphere and Planetary Electrodynamics Response Experiment (AMPERE) provides continuous global observations of Birkeland currents on a 10 minute cadence. During geomagnetic storms, currents intensify to over 15 MA, are dynamic both in intensity and distribution, and exhibit features not discernible in statistical analyses. For all of the subject grand challenge storms, AMPERE data reveal a number of novel phenomena illustrating the profound dynamics of the storm-time system. Storm-time onsets associated with shock arrivals are often very prompt and lead to dramatic surges in total current from 1 MA to over 5 MA in less than 20 minutes. The current surges occur predominantly on the dayside at high latitudes prior to any ring current or auroral expansions, indicating that neutral density upwelling is often driven independently of ring current or auroral zone intensifications. Rapid reconfigurations of the currents with IMF BY reversals within the sheath structures of coronal mass ejections (CMEs) are also common. This implies that convection of ionospheric density patches over the polar cap may be quite complex, particularly during the early phase of geomagnetic storms related to the CME sheath passage. The 3 September 2012 storm exhibited intense driving with classic quasi-stable Region 1 and 2 currents spanning 55 to 70 degrees magnetic latitude for over 10 hours at the beginning of the day, corresponding to stable southward IMF prior to shock arrival at noon on that day. The shock arrival and IMF southward intensification led to further expansion of the currents below 50 degrees magnetic latitude and to episodic surges in currents on the nightside, which is unique to storms. The resulting current structure showed multiple large-scale alternations in downward-upward-downward-upward direction that often occurs during intense, sustained driving during strong storms.

  16. Active Debris Removal - A Grand Engineering Challenge for the Twenty-First Century

    Science.gov (United States)

    Liou, Jer-Chyi

    2010-01-01

    , an active debris removal of about five objects per year is needed. The targets identified for removal are those with the highest mass and collision probability products. Analyses from the study indicate that the majority of those objects are spent upper stages with masses ranging from 1 to more than 8 metric tons, residing in several altitude regions and concentrated in about 10 inclination bands. To remove five of those objects per year in a cost-effective manner truly represents a grand challenge in engineering and technology development. An end-to-end debris removal operation includes, in general terms, launches orbit rendezvous, precision tracking, stabilization (of the tumbling motion), capture, and deorbit of the targets. An ADR system deigned to remove a single object is not very cost-effective. Therefore, the repeatability of the removal system is almost a requirement. Some of the technologies involved in the ADR process do exist, but the difficulty is to make them more cost effective. Other technologies, such as ways to stabilize a massive tumbling upper stage and the capture mechanisms, are new and will require major innovative research and development efforts. This paper summarizes an updated assessment of the environment, including what needs to be done to control the population growth, and outlines the major engineering and technology challenges to carry out active debris removal to preserve the environment.

  17. Environmental Biosciences Program Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2007-07-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the DOE. Plans for restructuring the performance schedule of the trichloroethylene projects have been submitted to the department. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this

  18. Environmental Biosciences Program Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2006-10-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this cooperative agreement can be forwarded to Dr. Lawrence C. Mohr in the EBP office of the Medical University of South Carolina at (843) 792-1532.

  19. Environmental Biosciences First Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2003-09-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risk issues. These initiatives are consistent with the Medical University's role as a comprehensive state-supported health sciences institution and the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable the Medical University to be a national resource for the scientific investigation of environmental health issues. EBP's success in convening worldwide scientific expertise is due in part to the inherent credibility the Medical University brings to the process of addressing these complex issues. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), asbestos and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  20. Environmental Biosciences Program Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2008-01-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the DOE. Plans for restructuring the performance schedule of the trichloroethylene projects have been submitted to the department. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  1. Grand Challenges of Advanced Computing for Energy Innovation Report from the Workshop Held July 31-August 2, 2012

    Energy Technology Data Exchange (ETDEWEB)

    Larzelere, Alex R.; Ashby, Steven F.; Christensen, Dana C.; Crawford, Dona L.; Khaleel, Mohammad A.; John, Grosh; Stults, B. Ray; Lee, Steven L.; Hammond, Steven W.; Grover, Benjamin T.; Neely, Rob; Dudney, Lee Ann; Goldstein, Noah C.; Wells, Jack; Peltz, Jim

    2013-03-06

    On July 31-August 2 of 2012, the U.S. Department of Energy (DOE) held a workshop entitled Grand Challenges of Advanced Computing for Energy Innovation. This workshop built on three earlier workshops that clearly identified the potential for the Department and its national laboratories to enable energy innovation. The specific goal of the workshop was to identify the key challenges that the nation must overcome to apply the full benefit of taxpayer-funded advanced computing technologies to U.S. energy innovation in the ways that the country produces, moves, stores, and uses energy. Perhaps more importantly, the workshop also developed a set of recommendations to help the Department overcome those challenges. These recommendations provide an action plan for what the Department can do in the coming years to improve the nation’s energy future.

  2. Grand Challenge Problem 10: TELEARC an Agile and Productive Networking of TEL Small and Medium Sized Research Labs

    DEFF Research Database (Denmark)

    Dirckinck-Holmfeld, Lone; Balacheff, Nicolas; Bottino, Rosa Maria;

    2016-01-01

    Small and medium sized research labs (SMLs) are dominating European TEL research. This is justified by the great numbers of countries and regions in Europe needing to develop a research and innovation competence to facilitate the diverse educational systems contextualized in various institutional...... settings across Europe. However, to strengthen the various research practices and to develop a common scientific language on TEL research the Grand Challenge Problem is to establish a vivid network and a community of practice among the research labs. TELEARC (Technology Enhanced Learning European Advanced...

  3. Environmental Biosciences Program Quarterly Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2009-01-30

    Current research projects have focused Environmental Biosciences Program (EBP) talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene, low-dose ionizing radiation (gamma and neutron) and alpha radiation from plutonium. Trichloroethylene research has been conducted as a joint collaborative effort with the University of Georgia. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the United States Department of Energy (DOE). Laboratory work has been completed on several trichloroethylene risk assessment projects, and these projects have been brought to a close. Plans for restructuring the performance schedule of the remaining trichloroethylene projects have been submitted to the department. A comprehensive manuscript on the scientific basis of trichloroethylene risk assessment is in preparation. Work on the low-dose radiation risk assessment projects is also progressing at a slowed rate as a result of funding uncertainties. It has been necessary to restructure the proponency and performance schedule of these projects, with the project on Low-Dose Radiation: Epidemiology Risk Models transferred to DOE Office of Science proponency under a separate funding instrument. Research on this project will continue under the provisions of the DOE Office of Science funding instrument, with progress reported in accordance with the requirements of that funding instrument. Progress on that project will no longer be reported in quarterly reports for DE-FC09-02CH11109. Following a meeting at the Savannah River Site on May 8, 2008, a plan was submitted for development of an epidemiological cohort study and prospective medical surveillance system for the assessment of disease rates among workers at the Savannah River

  4. Evaluation and comparison of current fetal ultrasound image segmentation methods for biometric measurements: a grand challenge.

    Science.gov (United States)

    Rueda, Sylvia; Fathima, Sana; Knight, Caroline L; Yaqub, Mohammad; Papageorghiou, Aris T; Rahmatullah, Bahbibi; Foi, Alessandro; Maggioni, Matteo; Pepe, Antonietta; Tohka, Jussi; Stebbing, Richard V; McManigle, John E; Ciurte, Anca; Bresson, Xavier; Cuadra, Meritxell Bach; Sun, Changming; Ponomarev, Gennady V; Gelfand, Mikhail S; Kazanov, Marat D; Wang, Ching-Wei; Chen, Hsiang-Chou; Peng, Chun-Wei; Hung, Chu-Mei; Noble, J Alison

    2014-04-01

    This paper presents the evaluation results of the methods submitted to Challenge US: Biometric Measurements from Fetal Ultrasound Images, a segmentation challenge held at the IEEE International Symposium on Biomedical Imaging 2012. The challenge was set to compare and evaluate current fetal ultrasound image segmentation methods. It consisted of automatically segmenting fetal anatomical structures to measure standard obstetric biometric parameters, from 2D fetal ultrasound images taken on fetuses at different gestational ages (21 weeks, 28 weeks, and 33 weeks) and with varying image quality to reflect data encountered in real clinical environments. Four independent sub-challenges were proposed, according to the objects of interest measured in clinical practice: abdomen, head, femur, and whole fetus. Five teams participated in the head sub-challenge and two teams in the femur sub-challenge, including one team who tackled both. Nobody attempted the abdomen and whole fetus sub-challenges. The challenge goals were two-fold and the participants were asked to submit the segmentation results as well as the measurements derived from the segmented objects. Extensive quantitative (region-based, distance-based, and Bland-Altman measurements) and qualitative evaluation was performed to compare the results from a representative selection of current methods submitted to the challenge. Several experts (three for the head sub-challenge and two for the femur sub-challenge), with different degrees of expertise, manually delineated the objects of interest to define the ground truth used within the evaluation framework. For the head sub-challenge, several groups produced results that could be potentially used in clinical settings, with comparable performance to manual delineations. The femur sub-challenge had inferior performance to the head sub-challenge due to the fact that it is a harder segmentation problem and that the techniques presented relied more on the femur's appearance

  5. A Case Study in Competitive Technical and Market Intelligence Support and Lessons Learned for the uChemLab LDRD Grand Challenge Project; TOPICAL

    International Nuclear Information System (INIS)

    The(mu)ChemLab(trademark) Laboratory Directed Research and Development (LDRD) Grand Challenge project began in October 1996 and ended in September 2000. The technical managers of the(mu)ChemLab(trademark) project and the LDRD office, with the support of a consultant, conducted a competitive technical and market demand intelligence analysis of the(mu)ChemLab(trademark). The managers used this knowledge to make project decisions and course adjustments. CTI/MDI positively impacted the project's technology development, uncovered potential technology partnerships, and supported eventual industry partner contacts. CTI/MDI analysis is now seen as due diligence and the(mu)ChemLab(trademark) project is now the model for other Sandia LDRD Grand Challenge undertakings. This document describes the CTI/MDI analysis and captures the more important ''lessons learned'' of this Grand Challenge project, as reported by the project's management team

  6. Governance Challenges in Joint Inter-Jurisdictional Management: The Grand Teton National Park, Wyoming, Elk Case

    Science.gov (United States)

    Clark, Susan G.; Vernon, Marian E.

    2015-08-01

    The controversial elk reduction program (elk hunt) in Grand Teton National Park, WY, has been a source of conflict since it was legislated in 1950. The hunt is jointly managed by the National Park Service and the Wyoming Game and Fish Department. This forced organizational partnership and the conflicting mandates of these two agencies have led to persistent conflict that seems irresolvable under the current decision-making process. To better understand the decision-making process and participant perspectives, we reviewed management documents, technical literature, and newspaper articles, and interviewed 35 key participants in this case. We used these data to analyze and appraise the adequacy of the decision-making process for the park elk hunt and to ask whether it reflects the common interest. We found deficiencies in all functions of the decision-making process. Neither the decisions made nor the process itself include diverse perspectives, nor do they attend to valid and appropriate participant concerns. Agency officials focus their attention on technical rather than procedural concerns, which largely obfuscates the underlying tension in the joint inter-jurisdictional management arrangement and ultimately contributes to the hunt's annual implementation to the detriment of the common interest. We offer specific yet widely applicable recommendations to better approximate an inclusive and democratic decision-making process that serves the community's common interests.

  7. Scientific Grand Challenges: Challenges in Climate Change Science and the Role of Computing at the Extreme Scale

    Energy Technology Data Exchange (ETDEWEB)

    Khaleel, Mohammad A.; Johnson, Gary M.; Washington, Warren M.

    2009-07-02

    The U.S. Department of Energy (DOE) Office of Biological and Environmental Research (BER) in partnership with the Office of Advanced Scientific Computing Research (ASCR) held a workshop on the challenges in climate change science and the role of computing at the extreme scale, November 6-7, 2008, in Bethesda, Maryland. At the workshop, participants identified the scientific challenges facing the field of climate science and outlined the research directions of highest priority that should be pursued to meet these challenges. Representatives from the national and international climate change research community as well as representatives from the high-performance computing community attended the workshop. This group represented a broad mix of expertise. Of the 99 participants, 6 were from international institutions. Before the workshop, each of the four panels prepared a white paper, which provided the starting place for the workshop discussions. These four panels of workshop attendees devoted to their efforts the following themes: Model Development and Integrated Assessment; Algorithms and Computational Environment; Decadal Predictability and Prediction; Data, Visualization, and Computing Productivity. The recommendations of the panels are summarized in the body of this report.

  8. Radical embodied cognitive neuroscience: addressing "grand challenges" of the mind sciences.

    Science.gov (United States)

    Favela, Luis H

    2014-01-01

    It is becoming ever more accepted that investigations of mind span the brain, body, and environment. To broaden the scope of what is relevant in such investigations is to increase the amount of data scientists must reckon with. Thus, a major challenge facing scientists who study the mind is how to make big data intelligible both within and between fields. One way to face this challenge is to structure the data within a framework and to make it intelligible by means of a common theory. Radical embodied cognitive neuroscience can function as such a framework, with dynamical systems theory as its methodology, and self-organized criticality as its theory. PMID:25339891

  9. The Application of Magnetic Techniques in Biosciences

    OpenAIRE

    Safarikova, M.; Safarik, I.

    2001-01-01

    The idea to use magnetic techniques in biosciences is not new, but it has enjoyed a resurgence of interest especially during the last two decades. Magnetic adsorbents, carriers and modifiers can be used for the immobilization, isolation, modification, detection, determination and removal of a variety of biologically active compounds, xenobiotics, cellular components and cells. Magnetic separation and labelling have recently found many useful and interesting applications in various areas of bi...

  10. Nitrogen-15 reference book: medicine and biosciences

    International Nuclear Information System (INIS)

    A comprehensive bibliography on the application of the stable nitrogen isotope 15N in medicine, animal nutrition and physiology, biosciences, and related disciplines is presented. The literature pertaining to this paper covers the period from 1977 to 1981. The references are completed by an index of all authors and a subject index with special emphasis to the used organisms, labelled compounds, and tracer techniques, respectively. (author)

  11. Innovation in a warming world. Research tackling Europe's grand challenge of climate change

    OpenAIRE

    Usanov, A.; Gehem, M.

    2012-01-01

    Climate change is arguably the largest environmental challenge facing humankind. Though the impact will be gradual and difficult to predict, we slowly start to understand how this process will affect our planet. The study "Innovation in a Warming World" spells out these effects, specifically for Europe, and shows what research and development efforts happen where. Finally, it suggests technologies and research areas that deserve increased attention (from advanced vehicles and studies on ‘tipp...

  12. Grand Challenges and Opportunities in Supply Chain Network Analysis and Design

    OpenAIRE

    Nagurney, Anna

    2011-01-01

    Pour visualiser la présentation cliquez sur le lien "En savoir plus sur cette publication" International audience Supply chain networks provide the backbones for our economies since they involve the production, storage, and distribution of products as varied as vaccines and medicines, food, high tech products, automobiles, clothing, and even energy. Many of the supply chains today are global in nature and time-sensitive and present challenging aspects for modeling and analysis. In this ...

  13. Grand Challenge Problem 2: Adaptive awareness for social regulation of emotions in online collaborative learning environments

    OpenAIRE

    Chanel, Guillaume; Lalanne, Denis; Lavoué, Elise; Lund, Kristine; Molinari, Gaëlle; Ringeval, Fabien; Weinberger, Armin

    2016-01-01

    Students’ ability to understand and manage emotions in self and others plays an important role in the success of collaborative learning (Järvenoja & Järvelä, 2009; Lajoie et al., 2015; Lavoué, Molinari, Prié, & Khezami, 2015). In online learning environments, the use of new social media technologies (blogs, forums, wikis, so-cial networking sites, etc.) facilitates connections between learners, but also may introduce new communication challenges. Moreover, the access of emotional cues (e.g., ...

  14. Bringing Vision-Based Measurements into our Daily Life: A Grand Challenge for Computer Vision Systems

    OpenAIRE

    Scharcanski, Jacob

    2016-01-01

    Bringing computer vision into our daily life has been challenging researchers in industry and in academia over the past decades. However, the continuous development of cameras and computing systems turned computer vision-based measurements into a viable option, allowing new solutions to known problems. In this context, computer vision is a generic tool that can be used to measure and monitor phenomena in wide range of fields. The idea of using vision-based measurements is appealing, since the...

  15. The Grand Challenges of Organ Banking: Proceedings from the first global summit on complex tissue cryopreservation.

    Science.gov (United States)

    Lewis, Jedediah K; Bischof, John C; Braslavsky, Ido; Brockbank, Kelvin G M; Fahy, Gregory M; Fuller, Barry J; Rabin, Yoed; Tocchio, Alessandro; Woods, Erik J; Wowk, Brian G; Acker, Jason P; Giwa, Sebastian

    2016-04-01

    The first Organ Banking Summit was convened from Feb. 27 - March 1, 2015 in Palo Alto, CA, with events at Stanford University, NASA Research Park, and Lawrence Berkeley National Labs. Experts at the summit outlined the potential public health impact of organ banking, discussed the major remaining scientific challenges that need to be overcome in order to bank organs, and identified key opportunities to accelerate progress toward this goal. Many areas of public health could be revolutionized by the banking of organs and other complex tissues, including transplantation, oncofertility, tissue engineering, trauma medicine and emergency preparedness, basic biomedical research and drug discovery - and even space travel. Key remaining scientific sub-challenges were discussed including ice nucleation and growth, cryoprotectant and osmotic toxicities, chilling injury, thermo-mechanical stress, the need for rapid and uniform rewarming, and ischemia/reperfusion injury. A variety of opportunities to overcome these challenge areas were discussed, i.e. preconditioning for enhanced stress tolerance, nanoparticle rewarming, cyroprotectant screening strategies, and the use of cryoprotectant cocktails including ice binding agents. PMID:26687388

  16. An Overview of Interdisciplinary Research at Notre Dame Addressing "Grand Challenges" in the Midwest and Great Lakes Region

    Science.gov (United States)

    Hamlet, A. F.; Bolster, D.; Tank, J. L.; Hellmann, J.; Christopher, S. F.; Sharma, A.; Chiu, C. M.

    2014-12-01

    The Midwest and Great Lakes region face a number of "Grand Challenges" associated with climate, land use, agriculture, and water resources infrastructure. These include sustainability of agricultural systems and related impacts to food security and the regional economy; sustainability of Great Lakes water levels; changing storm statistics and impacts to stormwater management and flooding; water quality in rivers and downstream receiving water bodies related to non-point source pollution on agricultural lands and combined sewer overflows in urban areas; urban impacts related to aging infrastructure and climate change, and ecosystem management and restoration. In the context of water management, groundwater resources are poorly understood in comparison with surface water resources, and regional-scale simulation models are needed to address questions of sustainability both in terms of supply and water quality. Interdisciplinary research at the University of Notre Dame is attempting to address these research challenges via 1) integrated macro-scale groundwater and surface water modeling to address issues related to sustainable water supply, ecosystem restoration, and agricultural impacts; 2) development of high-resolution regional climate models dynamically coupled to the Great Lakes to address urban impacts, changing storm statistics and to quantify precipitation and evaporation over the Great Lakes; 3) and integrated macro-scale hydrology and water quality modeling to assess the large-scale performance of innovative land management BMPs on agricultural land (such as the two-stage ditch, cover crops, and dynamic drainage control) intended to improve water quality.

  17. Understanding the Quran:a new grand challenge for computer science and artificial intelligence

    OpenAIRE

    Atwell, E; Habash, Nizar; Louw, Bill; Abu Shawar, Bayan; McEnery, Tony; Zaghouani, Wajdi; El-Haj, Mahmoud

    2010-01-01

    The Quran is held by Muslims to be a single-authored text, the direct words of God (Allah), conveyed by the angel Gabriel to Mohammed 1355-1378 years ago, and later transcribed verbatim to be used as the sole authoritative source of knowledge, wisdom and law. The challenge for computer scientists is to represent this knowledge, wisdom and law in computer systems: to build intelligent systems which can answer any question with knowledge from the Quran, and can help society, both Muslim and non...

  18. Developing Research Capabilities in Energy Biosciences

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Donald D

    2008-01-01

    Scientists founded the Life Sciences Research Foundation (LSRF) in 1983 as a non-profit pass through foundation that awards post doctoral fellowships in all areas of the life sciences. LSRF scientists review hundreds of applications each year from PhDs seeking support. For example this year, our 26th, we received 800 applications and our peer review committee will choose about 50 finalists who are eligible for these awards. We have no endowment so we solicit sponsors each year. The fellowships are sponsored by research oriented companies, foundations, philanthropists, the Howard Hughes Medical Institute, and other organizations who believe in the value of awarding fellowships to the best and the brightest young scientists. Our web site has a complete listing of all details about LSRF (http://www.lsrf.org/). In the late 1980s the Division of Bioscience in the Office of Basic Energy Science, a granting agency of the Department of Energy, joined this partnership. Bioscience's mandate was to support non-medical microbiology and plant sciences. LSRF received a series of 5 year grants from DOE to award fellowships to our top applicants in these fields of research. We began to support DOE-Energy Bioscience post doctoral fellows in 1989. From 1989 through 2004 when DOE funding ended our partnership awarded 41 DOE-Energy Bioscience Fellows of the Life Sciences Research Foundation. Each of these was a three year fellowship. DOE-Energy Biosciences was well matched with LSRF. Our extensive peer review screened applicants in all areas of the life sciences. Most LSRF sponsors are interested in supporting fellows who work on diseases. At the time that we began our partnership with DOE we had no sponsors willing to support plant biology and non medical microbiology. For 15 years DOE played a major role in the training of the very best young scientists in these important fields of research simply through its support of LSRF post doctoral fellows. Young scientists interested in

  19. Tipping Points and Balancing Acts: Grand Challenges and Synergistic Opportunities of Integrating Research and Education, Science and Solutions

    Science.gov (United States)

    McCaffrey, M. S.; Stroeve, J. C.

    2011-12-01

    The "Grand Challenges" to address Global Change identified by the International Council for Science (ICSU) and its partners through the Earth System Sustainability Initiative-improving forecasting, enhancing and integrating observation systems, confining and minimizing global environmental change, responding effectively to change, as well as innovating and evaluating these efforts-require an integrative approach that engages and inspires society in general and young people in particular. What are some of the effective strategies-and stumbling blocks-in being able to make Earth System science and related sustainability efforts relevant and practical to non-technical audiences? Recent climate education projects have pioneered new strategies toward linking and infusing research with education, science with solutions. For example, the Climate Literacy and Energy Awareness Network (CLEAN), a National Science Digital Library Pathway funded by NSF, has approached this integral approach by "closing the loop" between climate and energy topics, identifying and annotating high quality online resources relating to the carbon cycle and related topics. The Inspiring Climate Education Excellence (ICEE) project, funded by NASA, offers professional development for teachers that infuses climate science with solutions as an emerging "best practice" while being sensitive to the emotional, psychological and political aspects of avoiding "gloom and doom" on one hand or advocating for particular policy solutions on another. Other examples includes NASA's climate website (http://climate.nasa.gov ), which serves as a robust, engaging portal for climate research and data, especially for educators. The recent PBS series Earth: The Operators' Manual and related book and website are other recent example of how climate science research, education and solutions can be incorporated in a way that is appealing and informative. The Alliance for Climate Education (ACE) has given assemblies in

  20. Scientific Grand Challenges: Forefront Questions in Nuclear Science and the Role of High Performance Computing

    Energy Technology Data Exchange (ETDEWEB)

    Khaleel, Mohammad A.

    2009-10-01

    This report is an account of the deliberations and conclusions of the workshop on "Forefront Questions in Nuclear Science and the Role of High Performance Computing" held January 26-28, 2009, co-sponsored by the U.S. Department of Energy (DOE) Office of Nuclear Physics (ONP) and the DOE Office of Advanced Scientific Computing (ASCR). Representatives from the national and international nuclear physics communities, as well as from the high performance computing community, participated. The purpose of this workshop was to 1) identify forefront scientific challenges in nuclear physics and then determine which-if any-of these could be aided by high performance computing at the extreme scale; 2) establish how and why new high performance computing capabilities could address issues at the frontiers of nuclear science; 3) provide nuclear physicists the opportunity to influence the development of high performance computing; and 4) provide the nuclear physics community with plans for development of future high performance computing capability by DOE ASCR.

  1. Next-Generation Photon Sources for Grand Challenges in Science and Energy

    Energy Technology Data Exchange (ETDEWEB)

    None

    2009-05-01

    report identifies two aspects of energy science in which next-generation ultraviolet and X-ray light sources will have the deepest and broadest impact: (1) The temporal evolution of electrons, spins, atoms, and chemical reactions, down to the femtosecond time scale. (2) Spectroscopic and structural imaging of nano objects (or nanoscale regions of inhomogeneous materials) with nanometer spatial resolution and ultimate spectral resolution. The dual advances of temporal and spatial resolution promised by fourth-generation light sources ideally match the challenges of control science. Femtosecond time resolution has opened completely new territory where atomic motion can be followed in real time and electronic excitations and decay processes can be followed over time. Coherent imaging with short-wavelength radiation will make it possible to access the nanometer length scale, where intrinsic quantum behavior becomes dominant. Performing spectroscopy on individual nanometer-scale objects rather than on conglomerates will eliminate the blurring of the energy levels induced by particle size and shape distributions and reveal the energetics of single functional units. Energy resolution limited only by the uncertainty relation is enabled by these advances. Current storage-ring-based light sources and their incremental enhancements cannot meet the need for femtosecond time resolution, nanometer spatial resolution, intrinsic energy resolution, full coherence over energy ranges up to hard X-rays, and peak brilliance required to enable the new science outlined in this report. In fact, the new, unexplored territory is so expansive that no single currently imagined light source technology can fulfill the whole potential. Both technological and economic challenges require resolution as we move forward. For example, femtosecond time resolution and high peak brilliance are required for following chemical reactions in real time, but lower peak brilliance and high repetition rate are needed

  2. Communicating Geosciences with Policy-makers: a Grand Challenge for Academia

    Science.gov (United States)

    Harrison, W. J.; Walls, M. R.; Boland, M. A.

    2015-12-01

    Geoscientists interested in the broader societal impacts of their research can make a meaningful contribution to policy making in our changing world. Nevertheless, policy and public decision making are the least frequently cited Broader Impacts in proposals and funded projects within NSF's Geosciences Directorate. Academic institutions can play a lead role by introducing this societal dimension of our profession to beginning students, and by enabling interdisciplinary research and promoting communication pathways for experienced career geoscientists. Within the academic environment, the public interface of the geosciences can be presented through curriculum content and creative programs. These include undergraduate minors in economics or public policy designed for scientists and engineers, and internships with policy makers. Federal research institutions and other organizations provide valuable policy-relevant experiences for students. Academic institutions have the key freedom of mission to tackle interdisciplinary research challenges at the interface of geoscience and policy. They develop long-standing relationships with research partners, including national laboratories and state geological surveys, whose work may support policy development and analysis at local, state, regional, and national levels. CSM's Payne Institute for Earth Resources awards mini-grants for teams of researchers to develop collaborative research efforts between engineering/science and policy researchers. Current work in the areas of nuclear generation and the costs of climate policy and on policy alternatives for capturing fugitive methane emissions are examples of work at the interface between the geosciences and public policy. With academic engagement, geoscientists can steward their intellectual output when non-scientists translate geoscience information and concepts into action through public policies.

  3. Next-Generation Photon Sources for Grand Challenges in Science and Energy

    Energy Technology Data Exchange (ETDEWEB)

    None

    2009-05-01

    report identifies two aspects of energy science in which next-generation ultraviolet and X-ray light sources will have the deepest and broadest impact: (1) The temporal evolution of electrons, spins, atoms, and chemical reactions, down to the femtosecond time scale. (2) Spectroscopic and structural imaging of nano objects (or nanoscale regions of inhomogeneous materials) with nanometer spatial resolution and ultimate spectral resolution. The dual advances of temporal and spatial resolution promised by fourth-generation light sources ideally match the challenges of control science. Femtosecond time resolution has opened completely new territory where atomic motion can be followed in real time and electronic excitations and decay processes can be followed over time. Coherent imaging with short-wavelength radiation will make it possible to access the nanometer length scale, where intrinsic quantum behavior becomes dominant. Performing spectroscopy on individual nanometer-scale objects rather than on conglomerates will eliminate the blurring of the energy levels induced by particle size and shape distributions and reveal the energetics of single functional units. Energy resolution limited only by the uncertainty relation is enabled by these advances. Current storage-ring-based light sources and their incremental enhancements cannot meet the need for femtosecond time resolution, nanometer spatial resolution, intrinsic energy resolution, full coherence over energy ranges up to hard X-rays, and peak brilliance required to enable the new science outlined in this report. In fact, the new, unexplored territory is so expansive that no single currently imagined light source technology can fulfill the whole potential. Both technological and economic challenges require resolution as we move forward. For example, femtosecond time resolution and high peak brilliance are required for following chemical reactions in real time, but lower peak brilliance and high repetition rate are needed

  4. Combining Multidisciplinary Science, Quantitative Reasoning and Social Context to Teach Global Sustainability and Prepare Students for 21st Grand Challenges

    Science.gov (United States)

    Myers, J. D.

    2011-12-01

    The Earth's seven billion humans are consuming a growing proportion of the world's ecosystem products and services. Human activity has also wrought changes that rival the scale of many natural geologic processes, e.g. erosion, transport and deposition, leading to recognition of a new geological epoch, the Anthropocene. Because of these impacts, several natural systems have been pushed beyond the planetary boundaries that made the Holocene favorable for the expansion of humanity. Given these human-induced stresses on natural systems, global citizens will face an increasing number of grand challenges. Unfortunately, traditional discipline-based introductory science courses do little to prepare students for these complex, scientifically-based and technologically-centered challenges. With NSF funding, an introductory, integrated science course stressing quantitative reasoning and social context has been created at UW. The course (GEOL1600: Global Sustainability: Managing the Earth's Resources) is a lower division course designed around the energy-water-climate (EWC) nexus and integrating biology, chemistry, Earth science and physics. It melds lectures, lecture activities, reading questionnaires and labs to create a learning environment that examines the EWT nexus from a global through regional context. The focus on the EWC nexus, while important socially and intended to motivate students, also provides a coherent framework for identifying which disciplinary scientific principles and concepts to include in the course: photosynthesis and deep time (fossil fuels), biogeochemical cycles (climate), chemical reactions (combustion), electromagnetic radiation (solar power), nuclear physics (nuclear power), phase changes and diagrams (water and climate), etc. Lecture activities are used to give students the practice they need to make quantitative skills routine and automatic. Laboratory exercises on energy (coal, petroleum, nuclear power), water (in Bangladesh), energy

  5. Introducing bioinformatics, the biosciences' genomic revolution

    CERN Document Server

    Zanella, Paolo

    1999-01-01

    The general audience for these lectures is mainly physicists, computer scientists, engineers or the general public wanting to know more about what’s going on in the biosciences. What’s bioinformatics and why is all this fuss being made about it ? What’s this revolution triggered by the human genome project ? Are there any results yet ? What are the problems ? What new avenues of research have been opened up ? What about the technology ? These new developments will be compared with what happened at CERN earlier in its evolution, and it is hoped that the similiraties and contrasts will stimulate new curiosity and provoke new thoughts.

  6. Assessment of Collaboration and Interoperability in an Information Management System to Support Bioscience Research

    OpenAIRE

    Myneni, Sahiti; Patel, Vimla L.

    2009-01-01

    Biomedical researchers often have to work on massive, detailed, and heterogeneous datasets that raise new challenges of information management. This study reports an investigation into the nature of the problems faced by the researchers in two bioscience test laboratories when dealing with their data management applications. Data were collected using ethnographic observations, questionnaires, and semi-structured interviews. The major problems identified in working with these systems were rela...

  7. The Grand Narrative Revisited. Contemporary Flemish Novelists Take Up The Challenge To Create Plots Of The Flat World

    NARCIS (Netherlands)

    A. van Rooden

    2012-01-01

    Both in literature and philosophy it is assumed that the beginning of post-modernity coincides with the end of the so-called grand narrative. Referring to Philippe Lacoue-Labarthe’s last book L’"Allégorie", one could claim that since then, literary (re)presentation manifests itself as essentially ‘c

  8. Environmental Biosciences Quarterly Report, September - December, 2005

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2006-01-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  9. Environmental Biosciences Program Report for Year 2

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2005-10-15

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  10. Environmental Biosciences Program Fourth Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.d.

    2003-04-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific program, employing a range of research initiatives to identify, study and resolve environmental health risk issues. These initiatives are consistent with the Medical University's role as a comprehensive state-supported health sciences institution and the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable the Medical University to be a national resource for the scientific investigation of environmental health issues. EBP's success in convening worldwide scientific expertise is due in part to the inherent credibility the Medical University brings to the process of addressing these complex issues.

  11. The Bioscience Nuclear Microscopy Program at LLNL

    Energy Technology Data Exchange (ETDEWEB)

    Bench, G.; Freeman, S.; Roberts, M.; Sideras-Haddad, E.

    1996-12-31

    Since initiation in mid 1994, a bioscience nuclear microscopy program at Livermore has enabled collaboration with bio-scientists on a variety of projects requiring quantitative elemental microanalysis. For microprobe analysis a combination of PIXE and STIM are typically used; respectively generating element distribution maps with micron scale spatial resolution, and projected densities and histological information with sub-micron spatial resolution. Current studies demonstrate the applicability of nuclear microscopy (particularly when combined with other analysis techniques) in environmental tracing, toxicology, carcinogenesis, and structural biology. The program currently uses {approximately}10 percent of the available time on a 10 MV tandem accelerator that is also applied to a variety of Accelerator Mass Spectrometry and other microprobe programs. The completion of a dedicated nuclear microprobe system, using a 5 SDH NEC 1.7 MV tandem accelerator and employing several energy dispersive x-ray detectors to improve x-ray counting rates, promises increased accelerator access, greater sample throughput and continued expansion of the program.

  12. Environmental Biosciences Program Fourth Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2004-06-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), asbestos and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  13. Environmental Biosciences Program Third Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2004-03-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), asbestos and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  14. Environmental Biosciences Program Second Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2003-12-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), asbestos and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  15. Environmental Biosciences Program Report for Year Three

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2006-07-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  16. Second Quarter Report Environmental Biosciences Program

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2002-10-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific program, employing a range of research initiatives to identify, study and resolve environmental health risk issues. These initiatives are consistent with the Medical University's role as a comprehensive state-supported health sciences institution and the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable the Medical University to be a national resource for the scientific investigation of environmental health issues. EBP's success in convening worldwide scientific expertise is due in part to the inherent credibility the Medical University brings to the process of addressing these complex issues.

  17. Environmental Biosciences Program Third Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2003-01-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific program, employing a range of research initiatives to identify, study and resolve environmental health risk issues. These initiatives are consistent with the Medical University's role as a comprehensive state-supported health sciences institution and the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable the Medical University to be a national resource for the scientific investigation of environmental health issues. EBP's success in convening worldwide scientific expertise is due in part to the inherent credibility the Medical University brings to the process of addressing these complex issues.

  18. Lessons on Ethical Decision Making from the Bioscience Industry

    OpenAIRE

    Novas, Carlos

    2006-01-01

    Novas discusses the implications of a new study in PLoS Medicine, in which executives and senior managers from bioscience firms were asked what their companies were doing to promote ethical behaviour.

  19. Introducing Advances in Bioscience and Clinical Medicine (ABCmed)

    OpenAIRE

    Samad EJ Golzari; Kamyar Ghabili

    2013-01-01

    We are pleased to announce the launch of the Advances in Bioscience and Clinical Medicine (ABCmed), aninternational open-access, and peer-reviewed journal. Mostly intended to cover all areas of bioscience and medicine, theJournal would provide a unique venue for the scientists from all over the world to publish their scientific works. One ofthe advantages of publishing with us is the rapid yet rigorous review process which is mostly performed by ourdistinguished Editorial and Review Board mem...

  20. Developing and evaluating effective bioscience learning activities for nursing students.

    Science.gov (United States)

    Salvage-Jones, Judith; Hamill, Jessie; Todorovic, Michael; Barton, Matthew J; Johnston, Amy N B

    2016-07-01

    Effective engagement of nursing students in the study of biosciences remains a challenge for many tertiary institutes. In this study we attempted to implement and then evaluate a simple hands-on intervention, consisting of a series of hands-on games and puzzles, to increase nursing student engagement with core concepts and anatomical learning involved in clinical anatomy and physiology. The study used a quazi-experimental longitudinal before and after design, to explore the effect of a learning intervention on student performance. Set across three different campuses of the same University, it included 1320 first year undergraduate nursing students from 2013 to 2014 who were studying Anatomy and Physiology. Students were exposed to the interventions or not, and concomitant academic performance, weekly quiz scores, performance in fortnightly worksheets and, across the semester, exam performance were compared. The results show that while the intervention appeared to increase academic performance in students on one campus (2013) compared to the other two, this difference was not sustained into 2014 when a bigger cohort was examined. Despite significant subjective student satisfaction and enthusiasm about these learning and teaching interventions, the data does not support the capacity of these activities to enhance student academic performance. Tertiary entrance scores, being a non-native English speakers and socio-economic status all had a bigger impact on student performance than engagement with fun anatomy and physiology activities. PMID:27428695

  1. Foods: Where Innovation, Agriculture, Molecular Biosciences and Human Nutrition Meet

    Directory of Open Access Journals (Sweden)

    Charles Brennan

    2012-11-01

    Full Text Available There is one commodity the world over that unites mankind—food. In 2011 the United Nations claimed that the world’s population had reached the seven billion mark, a number which is set to increase dramatically in the decades to come. Food security, supply and sustainability are of paramount concern to the future economic and social progress of humanity. It is the responsibility of the food industry, together with food scientists and technologists, to shoulder the burden of ensuring an adequate supply of nutritious, safe and sensorially acceptable foods for a range of demanding consumers. In responding to this challenge, we need to understand the link between agriculture, engineering, food processing, molecular biosciences, human nutrition, commercialisation and innovation. Access to information concerning the composition and quality of foods has never been so easy for consumers and technologists alike. A plethora of research publications are made available each month to scientists and associated interested parties. The outcomes of these research manuscripts are often distilled and disseminated into messages available to everyone through bulletin boards, forums and the popular press. Newspapers and new agencies constantly report on the latest pharma-medical finding, or news regarding food safety and security concerns. We live in an age where information is so readily available to everyone that the task of finding credible and reputable data can be difficult at times. Providing sound evidenced based research is where a peer-reviewed journal can provide clarity. [...

  2. The ACCM Beamlines For Bioscience Studies

    International Nuclear Information System (INIS)

    To meet the increasing demand of X-ray beamlines for bioscience research, we have designed two high-performance, side-branch, asymmetric-cut curved crystal monochromator (ACCM) beamlines to fully utilize the sideway output of the superconducting wiggler SW6 at NSRRC. Each of these two beamlines (BL13A and BL13C) collects 1 mrad of the radiation fan in the horizontal direction, one centered at 3 mrad and the other at 4 mrad away from the central line of the wiggler output. The newly designed ACCMs are capable of energy scanning from 12 keV to 14 keV and offer good performances in terms of flux, resolution and stability. The ACCMs are designed and built in-house, combining efficient cooling and bending mechanisms in a compact unit that allows precise adjustments on a goniometer assembly. The bender is specially designed with symmetrically driven piezo-actuators that minimize center displacement during bending. Both direct and indirect cooling methods were tested; the former using Ga/In directly under the beam footprint and the latter using both sides of the crystal clamping area for cooling. Performance of the beamlines employing both cooling methods has been measured. The indirect cooling method provides 4.9 x 1010 photons/sec through a pair of 100 μm slits (H x V) with energy resolution of 5.3 x 10-3 (ΔE/E) at 12.7 keV. Higher energy resolution in the 10-4 range can be achieved by adjusting the horizontal source fan or the crystal radius at the expense of flux. The direct cooling method provides 1.4 x 1010 photons/sec through a pair of 100 μm slits (H x V) with energy resolution of 1.2 x 10-3 (ΔE/E) at 12.7 keV. The FWHM of the focused beam profile in the indirect cooling mode is 800 x 109 μm (H x V), and 800 x 283 μm (H x V) in the direct cooling mode with some horizontal tail, the latter being larger due to influence of the Ga/In layer on the crystal shape. Cooling efficiency is excellent in the direct cooling mode, in which the performance stabilizes in a

  3. Environmental Biosciences Program Fourth Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2005-06-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation s need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyles (PCBs), and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this cooperative agreement can be forwarded to Dr. Lawrence C. Mohr in the EBP office of the Medical University of South Carolina at (843) 792-1532.

  4. Environmental Biosciences Report for Year 3

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2007-10-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the DOE. Plans for restructuring the performance schedule of the trichloroethylene projects have been submitted to the department. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk based decision-making. Questions, comments or requests for further information concerning the activities under this

  5. Environmental Biosciences Program Second Quarter Report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2004-12-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this cooperative agreement can be forwarded to Dr. Lawrence C. Mohr in the EBP office of the Medical University of South Carolina at (843) 792-1532.

  6. Environmental Biosciences Program Report for Year 3

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2007-04-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the DOE. Plans for restructuring the performance schedule of the trichloroethylene projects have been submitted to the department. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making. Questions, comments or requests for further information concerning the activities under this

  7. The use of the Climate-science Computational End Station (CCES) development and grand challenge team for the next IPCC assessment: an operational plan

    International Nuclear Information System (INIS)

    The grand challenge of climate change science is to predict future climates based on scenarios of anthropogenic emissions and other changes resulting from options in energy and development policies. Addressing this challenge requires a Climate Science Computational End Station consisting of a sustained climate model research, development, and application program combined with world-class DOE leadership computing resources to enable advanced computational simulation of the Earth system. This project provides the primary computer allocations for the DOE SciDAC and Climate Change Prediction Program. It builds on the successful interagency collaboration of the National Science and the U.S. Department of Energy in developing and applying the Community Climate System Model (CCSM) for climate change science. It also includes collaboration with the National Aeronautics and Space Administration in carbon data assimilation and university partners with expertise in high-end computational climate research

  8. Teaching and learning about bioscience ethics with undergraduates.

    Science.gov (United States)

    Van Rooy, Wilhelmina; Pollard, Irina

    2002-01-01

    Bioscience ethics acts as a practical interface between science and bioethics. It links scientific endeavour and its application into adaptive forms of bioethical consensus. Its major elements are increased understanding of biological systems, responsible use of technology, and curtailment of ethnocentric debates in tune with new scientific insights. This paper briefly describes the students' learning experience gained from the vacation unit BIOL 240, Introduction to Bioscience Ethics, as taught in biology, Macquarie University. On the basis of our evidence students were overwhelmingly positive about their learning because the unit assisted them to better face dilemmas that arise from the application of science and technology. The structure also provided active engagement with the subject matter and preferred learning environments that supported and contested their understanding of concepts relevant to bioscience and bioethics. PMID:14741947

  9. Key Concepts for and Assessment of an Undergraduate Class that Engages Engineering Students in Climate Change Grand Challenge

    Science.gov (United States)

    Powers, S. E.; DeWaters, J.; Dhaniyala, S.

    2015-12-01

    Engineers must take a leading role in addressing the challenges of mitigating climate change and adapting to the inevitable changes that our world is facing. Yet climate change classes targeting engineering students are scarce. Technical education must focus on the problem formulation and solutions that consider multiple, complex interactions between engineered systems and the Earth's climate system and recognize that transformation raises societal challenges, including trade-offs among benefits, costs, and risks. Moreover, improving engineering students' climate science literacy will require strategies that also inspire students' motivation to work toward their solution. A climate science course for engineers has been taught 5 semesters as part of a NASA Innovations in Climate Education program grant (NNXlOAB57A). The basic premise of this project was that effective instruction must incorporate scientifically-based knowledge and observations and foster critical thinking, problem solving, and decision-making skills. Lecture, in-class cooperative and computer-based learning and a semester project provide the basis for engaging students in evaluating effective mitigation and adaptation solutions. Policy and social issues are integrated throughout many of the units. The objective of this presentation is to highlight the content and pedagogical approach used in this class that helped to contribute to significant gains in engineering students' climate literacy and critical thinking competencies. A total of 89 students fully participated in a pre/post climate literacy questionnaire. As a whole, students demonstrated significant gains in climate-related content knowledge (pAssessment of semester project reports with a critical thinking rubric showed that the students did an excellent job of formulating problem statements and solutions in a manner that incorporated a multidimensional systems perspective. These skills are sometimes foreign to technically focused, number

  10. Key Concepts for and Assessment of an Undergraduate Class that Engages Engineering Students in Climate Change Grand Challenge

    Science.gov (United States)

    Powers, S. E.; DeWaters, J.; Dhaniyala, S.

    2015-12-01

    Engineers must take a leading role in addressing the challenges of mitigating climate change and adapting to the inevitable changes that our world is facing. Yet climate change classes targeting engineering students are scarce. Technical education must focus on the problem formulation and solutions that consider multiple, complex interactions between engineered systems and the Earth's climate system and recognize that transformation raises societal challenges, including trade-offs among benefits, costs, and risks. Moreover, improving engineering students' climate science literacy will require strategies that also inspire students' motivation to work toward their solution. A climate science course for engineers has been taught 5 semesters as part of a NASA Innovations in Climate Education program grant (NNXlOAB57A). The basic premise of this project was that effective instruction must incorporate scientifically-based knowledge and observations and foster critical thinking, problem solving, and decision-making skills. Lecture, in-class cooperative and computer-based learning and a semester project provide the basis for engaging students in evaluating effective mitigation and adaptation solutions. Policy and social issues are integrated throughout many of the units. The objective of this presentation is to highlight the content and pedagogical approach used in this class that helped to contribute to significant gains in engineering students' climate literacy and critical thinking competencies. A total of 89 students fully participated in a pre/post climate literacy questionnaire. As a whole, students demonstrated significant gains in climate-related content knowledge (p<0.001), affect (p<0.001), and behavior (p=0.002). Mean post scores were above a 'passing' cutoff (70%) for all three subscales. Assessment of semester project reports with a critical thinking rubric showed that the students did an excellent job of formulating problem statements and solutions in a

  11. Software Engineering Support of the Third Round of Scientific Grand Challenge Investigations: Earth System Modeling Software Framework Survey

    Science.gov (United States)

    Talbot, Bryan; Zhou, Shu-Jia; Higgins, Glenn; Zukor, Dorothy (Technical Monitor)

    2002-01-01

    One of the most significant challenges in large-scale climate modeling, as well as in high-performance computing in other scientific fields, is that of effectively integrating many software models from multiple contributors. A software framework facilitates the integration task, both in the development and runtime stages of the simulation. Effective software frameworks reduce the programming burden for the investigators, freeing them to focus more on the science and less on the parallel communication implementation. while maintaining high performance across numerous supercomputer and workstation architectures. This document surveys numerous software frameworks for potential use in Earth science modeling. Several frameworks are evaluated in depth, including Parallel Object-Oriented Methods and Applications (POOMA), Cactus (from (he relativistic physics community), Overture, Goddard Earth Modeling System (GEMS), the National Center for Atmospheric Research Flux Coupler, and UCLA/UCB Distributed Data Broker (DDB). Frameworks evaluated in less detail include ROOT, Parallel Application Workspace (PAWS), and Advanced Large-Scale Integrated Computational Environment (ALICE). A host of other frameworks and related tools are referenced in this context. The frameworks are evaluated individually and also compared with each other.

  12. Meeting the Grand Challenge of Protecting Astronauts Health: Electrostatic Active Space Radiation Shielding for Deep Space Missions

    Science.gov (United States)

    Tripathi, Ram K.

    2016-01-01

    membrane structure (EIMS) in both charged and uncharged configurations. The amount of charge shielding behind and around the EIMS was studied for different combinations of membrane structure voltages and electron energies. Both passive and active shielding were observed, with active shielding capable of deflecting nearly all incoming electrons. The pattern of charge distribution around the structure was studied as well as the stability of the structures in the charge flow. The charge deflection experiments illustrate that the EIMS remain inflated during charge deflection, but will experience small amplitude oscillations. Investigations were performed to determine a potential cause of the vibrations. It is postulated these vibrations are due to the charge flux causing local membrane charge distribution changes. As the membrane structure inflation pressure is changed, the shape responds, and causes the observed sustained vibration. Having identified this phenomenon is important when considering electrostatically inflated membrane structures (EIMS) in a space environment. Additionally, this project included a study of membrane material impacts, specifically the impact of membrane thickness. Extremely thin materials presented new challenges with vacuum preparation techniques and rapid charging. The thinner and lighter membrane materials were successfully inflated using electrostatic forces in a vacuum chamber. However, care must be taken when varying the potentials of such lighter structures as the currents can cause local heating and melting of the very thin membranes. Lastly, a preliminary analysis is performed to study rough order of magnitude power requirements for using EIMS for radiation shielding. The EIMS power requirement becomes increasingly more challenging as the spacecraft voltage is increased. As a result, the emphasis is on the deflection of charges away from the spacecraft rather than totally stopping them. This significantly alleviates the initial power

  13. The Numerical Tokamak Project (NTP) simulation of turbulent transport in the core plasma: A grand challenge in plasma physics

    International Nuclear Information System (INIS)

    The long-range goal of the Numerical Tokamak Project (NTP) is the reliable prediction of tokamak performance using physics-based numerical tools describing tokamak physics. The NTP is accomplishing the development of the most advanced particle and extended fluid model's on massively parallel processing (MPP) environments as part of a multi-institutional, multi-disciplinary numerical study of tokamak core fluctuations. The NTP is a continuing focus of the Office of Fusion Energy's theory and computation program. Near-term HPCC work concentrates on developing a predictive numerical description of the core plasma transport in tokamaks driven by low-frequency collective fluctuations. This work addresses one of the greatest intellectual challenges to our understanding of the physics of tokamak performance and needs the most advanced computational resources to progress. We are conducting detailed comparisons of kinetic and fluid numerical models of tokamak turbulence. These comparisons are stimulating the improvement of each and the development of hybrid models which embody aspects of both. The combination of emerging massively parallel processing hardware and algorithmic improvements will result in an estimated 10**2--10**6 performance increase. Development of information processing and visualization tools is accelerating our comparison of computational models to one another, to experimental data, and to analytical theory, providing a bootstrap effect in our understanding of the target physics. The measure of success is the degree to which the experimentally observed scaling of fluctuation-driven transport may be predicted numerically. The NTP is advancing the HPCC Initiative through its state-of-the-art computational work. We are pushing the capability of high performance computing through our efforts which are strongly leveraged by OFE support

  14. Dispatches from the Interface of Salivary Bioscience and Neonatal Research

    OpenAIRE

    KristinVoegtline; DouglasA.Granger

    2014-01-01

    The emergence of the interdisciplinary field of salivary bioscience has created opportunity for neonatal researchers to measure multiple components of biological systems non-invasively in oral fluids. The implications are profound and potentially high impact. From a single oral fluid specimen, information can be obtained about a vast array of biological systems (e.g., endocrine, immune, autonomic nervous system) and the genetic polymorphisms related to individual differences in their function...

  15. Bioscience methodologies in physical chemistry an engineering and molecular approach

    CERN Document Server

    D'Amore, Alberto

    2013-01-01

    The field of bioscience methodologies in physical chemistry stands at the intersection of the power and generality of classical and quantum physics with the minute molecular complexity of chemistry and biology. This book provides an application of physical principles in explaining and rationalizing chemical and biological phenomena. It does not stick to the classical topics that are conventionally considered as part of physical chemistry; instead it presents principles deciphered from a modern point of view, which is the strength of this book.

  16. Fluorescence lifetime imaging in biosciences: technologies and applications

    Institute of Scientific and Technical Information of China (English)

    Raluca NIESNER; Karl-Heinz GERICKE

    2008-01-01

    The biosciences require the development of methods that allow a non-invasive and rapid investigation of biological systems. In this aspect, high-end imaging tech-niques allow intravital microscopy in real-time, providing information on a molecular basis. Far-field fluorescence imaging techniques are some of the most adequate methods for such investigations. However, there are great differences between the common fluorescence imaging techniques, i.e., wide-field, confocal one-photon and two-photon microscopy, as far as their applicability in diverse bioscientific research areas is concerned. In the first part of this work, we briefly compare these techniques. Standard methods used in the biosciences, i.e., steady-state techniques based on the analy-sis of the total fluorescence signal originating from the sam-ple, can successfully be employed in the study of cell, tissue and organ morphology as well as in monitoring the macro-scopic tissue function. However, they are mostly inadequate for the quantitative investigation of the cellular function at the molecular level. The intrinsic disadvantages of steady-state techniques are countered by using time-resolved tech-niques. Among these fluorescence lifetime imaging (FLIM) is currently the most common. Different FLIM principles as well as applications of particular relevance for the biosci-ences, especially for fast intravital studies are discussed in this work.

  17. On the outside looking in: redefining the role of analytical chemistry in the biosciences.

    Science.gov (United States)

    Hare, Dominic J; New, Elizabeth J

    2016-07-12

    Biomedical research has moved on from the study of the structure of organs, cells and organelles. Today, the key questions that must be addressed to understand the body in health and disease are related to fundamental biochemistry: the distribution and speciation of chemicals, the regulation of chemical reactions, and the control of chemical environments. To see advances in this field, it is essential for analytical chemists to actively engage in this process, from beginning to end. In this Feature Article, we review the progress that has been made towards gaining an understanding of the chemistry of the body, while commenting on the intrinsic disconnect between new innovations in the field of analytical chemistry and practical application within the biosciences. We identify the challenges that prevent chemists from making a greater impact in this field, and highlight key steps for moving forward. PMID:26898242

  18. Assessment of Collaboration and Interoperability in an Information Management System to Support Bioscience Research

    Science.gov (United States)

    Myneni, Sahiti; Patel, Vimla L.

    2009-01-01

    Biomedical researchers often have to work on massive, detailed, and heterogeneous datasets that raise new challenges of information management. This study reports an investigation into the nature of the problems faced by the researchers in two bioscience test laboratories when dealing with their data management applications. Data were collected using ethnographic observations, questionnaires, and semi-structured interviews. The major problems identified in working with these systems were related to data organization, publications, and collaboration. The interoperability standards were analyzed using a C4I framework at the level of connection, communication, consolidation, and collaboration. Such an analysis was found to be useful in judging the capabilities of data management systems at different levels of technological competency. While collaboration and system interoperability are the “must have” attributes of these biomedical scientific laboratory information management applications, usability and human interoperability are the other design concerns that must also be addressed for easy use and implementation. PMID:20351900

  19. Big Data and Grand Challenges

    DEFF Research Database (Denmark)

    Finnemann, Niels Ole

    2016-01-01

    Presentation at workshop on ‘Digital Humanities – Directions and Horizons’, June 21, 2016. Center for Communication and Computing, University of Copenhagen. Denmark (KUA Building 27, Room 27.O.17)...

  20. SBBN 2010: 7. Congress of the Brazilian Society of Nuclear Biosciences. Radiations in biosciences: advances and trends

    International Nuclear Information System (INIS)

    Advance and new perspectives related to the use of ionizing and no ionizing radiations in nuclear biosciences are presented. Multidisciplinary approach, including radiopharmacy, radioprotection and dosimetry, cytogenetic, biosafety, radioecology, environmental toxicology are studied. Topics of Nuclear medicine, radiotherapy and image diagnosis, such as computerized tomography, PET scan, phantoms, biomedical radiography, are reported. Use of radioisotopes, evaluation of radiation dose rates, radiation dose distribution, radiation monitoring is considered. Environmental impact of radiation are also in human beings, animals and for several purposes are analyzed. (MAC)

  1. Students Turned Off by Turnitin? Perception of Plagiarism and Collusion by Undergraduate Bioscience Students

    Science.gov (United States)

    Thompsett, Andrew; Ahluwalia, Jatinder

    2010-01-01

    Research on undergraduate bioscience students and the incidence of plagiarism is still in its infancy and a key problem arises in gauging the perception of undergraduate students on plagiarism and collusion in biosciences subjects because of the lack of empirical data. The aim of this study was to provide qualitative data on the perceptions of…

  2. Call for Papers-Bioscience Methods(ISSN 1925-1920)

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Bioscience Methods (BM) (ISSN 1925-1920) is a new launched, open access and peer-reviewed journal that dedicates to publish the original research papers involving in innovative technologies and novel experimental arts within the fields of biosciences.

  3. Applications of computational tools in biosciences and medical engineering

    CERN Document Server

    Altenbach, Holm

    2015-01-01

     This book presents the latest developments and applications of computational tools related to the biosciences and medical engineering. It also reports the findings of different multi-disciplinary research projects, for example, from the areas of scaffolds and synthetic bones, implants and medical devices, and medical materials. It is also shown that the application of computational tools often requires mathematical and experimental methods. Computational tools such as the finite element methods, computer-aided design and optimization as well as visualization techniques such as computed axial tomography open up completely new research fields that combine the fields of engineering and bio/medical. Nevertheless, there are still hurdles since both directions are based on quite different ways of education. Often even the “language” can vary from discipline to discipline.

  4. Division of Agro technology and Biosciences: Past, Present and Future

    International Nuclear Information System (INIS)

    In presenter speech, he outlined several topics regarding development of Agro technology and Biosciences Division from 31 years ago. This division started with Unit Sains Hidupan Liar under PUSPATI in 1981 and change their names to Program Isotop dan Sinaran dalam Biologi dan Pertanian under Nuclear Technology Unit (UTN) (1983). In 1990 their premise change to MINT-Tech Park. This program responsible for conducting research in agro technology using nuclear technology. Several achievements achieved by this division since established. They also succeed in mutating banana namely Novaria banana (1994), Tongkat Ali rice (1990), ground nut (2003), orchids, organic fertilizer and foliage in 2000. The vision of this division are to promote and enhance innovation and applications in nuclear technology to achieve security in food productivity, safety and quality and ecological awareness for economics competitiveness and vibrancy in agrobioindustry and community development. (author)

  5. Dispatches from the Interface of Salivary Bioscience and Neonatal Research

    Directory of Open Access Journals (Sweden)

    KristinVoegtline

    2014-03-01

    Full Text Available The emergence of the interdisciplinary field of salivary bioscience has created opportunity for neonatal researchers to measure multiple components of biological systems non-invasively in oral fluids. The implications are profound and potentially high impact. From a single oral fluid specimen, information can be obtained about a vast array of biological systems (e.g., endocrine, immune, autonomic nervous system and the genetic polymorphisms related to individual differences in their function. The purpose of this review is to describe the state of the art for investigators interested in integrating these unique measurement tools into the current and next generation of research on gonadal steroid exposure during the prenatal and neonatal developmental periods

  6. Introducing Advances in Bioscience and Clinical Medicine (ABCmed

    Directory of Open Access Journals (Sweden)

    Samad EJ Golzari

    2013-07-01

    Full Text Available We are pleased to announce the launch of the Advances in Bioscience and Clinical Medicine (ABCmed, aninternational open-access, and peer-reviewed journal. Mostly intended to cover all areas of bioscience and medicine, theJournal would provide a unique venue for the scientists from all over the world to publish their scientific works. One ofthe advantages of publishing with us is the rapid yet rigorous review process which is mostly performed by ourdistinguished Editorial and Review Board members; this obviously hard-to-achieve goal would not be realized withouttheir continuous support and advice.Another distinguishing characteristic of ABCmed is the diversity of published items in each issue. The editorial team ofthe Journal has devoted separate sections to rather unknown yet interesting fields of the science for instance hypotheses,history of medicine, etc. In the first issue of ABCmed, the readers might refer to the two published hypotheseshighlighting the possible role of chamomile in the treatment of rheumatoid arthritis, and also the preventive effects oftadalafil together with nimodipine in subarachnoid hemorrhage-induced cerebral vasospasm.Letters to the Editor are one of the major sectors in the ABCmed providing not only further on the already publisheddata in the Journal, but also personal comments on the major public health concerns and medical issues. In the firstissue of the Journal, a very important cancer surgery complication is debated, introducing different strategies in the painmanagement of breast cancer patients.We hope that ABCmed will provide a basis to bring together the scientists from all over the globe with the same goal ofpromoting science.

  7. Final report on grand challenge LDRD project : a revolution in lighting : building the science and technology base for ultra-efficient solid-state lighting.

    Energy Technology Data Exchange (ETDEWEB)

    Copeland, Robert Guild; Mitchell, Christine Charlotte; Follstaedt, David Martin; Lee, Stephen Roger; Shul, Randy John; Fischer, Arthur Joseph; Chow, Weng Wah Dr.; Myers, Samuel Maxwell, Jr.; Thoma, Steven George; Gee, James Martin; Coltrin, Michael Elliott; Burdick, Brent A.; Salamone, Angelo, L., Jr.; Hadley, G. Ronald; Elliott, Russell D.; Campbell, Jonathan M.; Abrams, Billie Lynn; Wendt, Joel Robert; Pawlowski, Roger Patrick; Simpson, Regina Lynn; Kurtz, Steven Ross; Cole, Phillip James; Fullmer, Kristine Wanta; Seager, Carleton Hoover; Bogart, Katherine Huderle Andersen; Biefeld, Robert Malcolm; Kerley, Thomas M.; Norman, Adam K.; Tallant, David Robert; Woessner, Stephen Matthew; Figiel, Jeffrey James; Moffat, Harry K.; Provencio, Paula Polyak; Emerson, John Allen; Kaplar, Robert James; Wilcoxon, Jess Patrick; Waldrip, Karen Elizabeth; Rohwer, Lauren Elizabeth Shea; Cross, Karen Charlene; Wright, Alan Francis; Gonzales, Rene Marie; Salinger, Andrew Gerhard; Crawford, Mary Hagerott; Garcia, Marie L.; Allen, Mark S.; Southwell, Edwin T. (Perspectives, Sedona, AZ); Bauer, Tom M.; Monson, Mary Ann; Tsao, Jeffrey Yeenien; Creighton, James Randall; Allerman, Andrew Alan; Simmons, Jerry A.; Boyack, Kevin W.; Jones, Eric Daniel; Moran, Michael P.; Pinzon, Marcia J. (Perspectives, Sedona, AZ); Pinson, Ariane O. (Perspectives, Sedona, AZ); Miksovic, Ann E. (Perspectives, Sedona, AZ); Wang, George T.; Ashby, Carol Iris Hill; Missert, Nancy A.; Koleske, Daniel David; Rahal, Nabeel M.

    2004-06-01

    This SAND report is the final report on Sandia's Grand Challenge LDRD Project 27328, 'A Revolution in Lighting -- Building the Science and Technology Base for Ultra-Efficient Solid-state Lighting.' This project, which for brevity we refer to as the SSL GCLDRD, is considered one of Sandia's most successful GCLDRDs. As a result, this report reviews not only technical highlights, but also the genesis of the idea for Solid-state Lighting (SSL), the initiation of the SSL GCLDRD, and the goals, scope, success metrics, and evolution of the SSL GCLDRD over the course of its life. One way in which the SSL GCLDRD was different from other GCLDRDs was that it coincided with a larger effort by the SSL community - primarily industrial companies investing in SSL, but also universities, trade organizations, and other Department of Energy (DOE) national laboratories - to support a national initiative in SSL R&D. Sandia was a major player in publicizing the tremendous energy savings potential of SSL, and in helping to develop, unify and support community consensus for such an initiative. Hence, our activities in this area, discussed in Chapter 6, were substantial: white papers; SSL technology workshops and roadmaps; support for the Optoelectronics Industry Development Association (OIDA), DOE and Senator Bingaman's office; extensive public relations and media activities; and a worldwide SSL community website. Many science and technology advances and breakthroughs were also enabled under this GCLDRD, resulting in: 55 publications; 124 presentations; 10 book chapters and reports; 5 U.S. patent applications including 1 already issued; and 14 patent disclosures not yet applied for. Twenty-six invited talks were given, at prestigious venues such as the American Physical Society Meeting, the Materials Research Society Meeting, the AVS International Symposium, and the Electrochemical Society Meeting. This report contains a summary of these science and technology

  8. Environmental Biosciences Program Quarterly Report for Year 3

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2006-04-30

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems. Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  9. Environmental Biosciences Program Third Quarter Report, Year 2

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr, M.D.

    2005-03-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC09-02CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific research program, employing a range of research initiatives to identify, study and resolve environmental health risks. These initiatives are consistent with the MUSC role as a comprehensive state-supported health sciences institution and with the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable MUSC to be a national resource for the scientific investigation of environmental health issues. EBPs success as a nationally prominent research program is due, in part, to its ability to task-organize scientific expertise from multiple disciplines in addressing these complex problems Current research projects have focused EBP talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene (TCE), polychlorinated biphenyls (PCBs), and low-dose ionizing radiation. A project is also being conducted in the use of geographical information system technology to analyze population health risks related to environmental hazards as a tool for risk-based decision-making.

  10. MUSC Environmental Biosciences Program First Quarter Report May - June, 2002

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence C. Mohr

    2002-07-31

    In May 2002, the United States Department of Energy (DOE) signed Assistance Instrument Number DE-FC02-98CH11109 with the Medical University of South Carolina (MUSC) to support the Environmental Biosciences Program (EBP). This funding instrument replaces DOE Assistance Instrument Number DE-FC02-98CH10902. EBP is an integrated, multidisciplinary scientific program, employing a range of research initiatives to identify, study and resolve environmental health risk issues. These initiatives are consistent with the Medical University's role as a comprehensive state-supported health sciences institution and the nation's need for new and better approaches to the solution of a complex and expansive array of environment-related health problems. The intrinsic capabilities of a comprehensive health sciences institution enable the Medical University to be a national resource for the scientific investigation of environmental health issues. EBP's success in convening worldwide scientific expertise is due in part to the inherent credibility the Medical University brings to the process of addressing these complex issues.

  11. Nuclear medicine department activity facing major public health challenges in France; Activite des services de medecine nucleaire face aux grands enjeux de sante publique en France

    Energy Technology Data Exchange (ETDEWEB)

    Baulieu, J.L. [Hopital Bretonneau, CHU de Tours, Unite de Medecine Nucleaire, 37 - Tours (France); Mundler, O. [CHU la Timone, Service Central de Biophysique et Medecine Nucleaire, 13 - Marseille (France)

    2007-12-15

    A national survey was made at the 2008 la Baule Symposium 'nuclear medicine facing major public health challenges'. The aim was to evaluate the activity in the fields of clinical specialities involved in these challenges : cancerology, cardiology and neurology. The response rate was 62%. The total number of PET scans performed in France during the year 2007 was about 100,000 including 97.5% of cancer indications. The mean number of PET scans per center was 1285, with a maximum of 3500 scans. The first indications were lung cancer (27%), lymphoma (20%) and colorectal cancer (14%). The registered number of cardiac examinations was 170,387 extrapolated to a total number of about 250,000 examinations in one year. The number of registered brain SPECT was 11,215 corresponding to about 100 examinations per center in one year. The survey pointed out large variations of PET activity between centers and suggested potentialities in extending and diversifying the field of PET. Brain scintigraphy appeared as a minor sector out of proportion with the challenge of degenerative brain pathology. Performing again these evaluations in the next years should allow to better describe the capabilities of nuclear medicine to face the major challenges and the evolution of public health.

  12. Giving a grand rounds presentation.

    Science.gov (United States)

    Morrison, Laura J; Portenoy, Russell

    2010-12-01

    Giving a Grand Rounds presentation provides the hospice and palliative medicine subspecialist with the occasion to participate in a time-honored and respected event. It remains an opportunity to promote the discipline, support institutional culture change, and favorably influence the attitudes, knowledge, skills, and performance of colleagues. For those pursuing academic careers, it also is a chance to establish academic currency and develop teaching and presentation skills. In most academic settings, the format of Grand Rounds has shifted over time from a patient and problem-based discussion to a didactic, topic-focused lecture. A body of literature questions the value of this shift toward a more passive learner. Limited evidence prevents a definitive answer but many advocate for the integration of more interactive methods to improve the effectiveness of Grand Rounds. This article provides a flexible framework to guide those preparing to give a Grand Rounds and those teaching and supporting others to do so. To do this well, adult learning principles must be thoughtfully incorporated into a presentation style and method appropriate to the venue. The approach emphasizes learner-centeredness, interactive strategies, and evaluation. Room for creativity exists at every step and can add enjoyment and challenge along the way. PMID:21155643

  13. Reflective Writing as a Tool for Assessing Teamwork in Bioscience: Insights into Student Performance and Understanding of Teamwork

    Science.gov (United States)

    Mayne, Lynne

    2012-01-01

    To ensure a modern bioscience curriculum that responds to the current needs of stakeholders, there is a need to embed a range of generic capabilities that enables graduates to succeed in and contribute to a rapidly changing world, as well as building strong bioscience skills and knowledge. The curriculum must also prepare students for a rapidly…

  14. Design of an Integrated Team Project as Bachelor Thesis in Bioscience Engineering

    Science.gov (United States)

    Peeters, Marie-Christine; Londers, Elsje; Van der Hoeven, Wouter

    2014-01-01

    Following the decision at the KU Leuven to implement the educational concept of guided independent learning and to encourage students to participate in scientific research, the Faculty of Bioscience Engineering decided to introduce a bachelor thesis. Competencies, such as communication, scientific research and teamwork, need to be present in the…

  15. Reflective Practice: A Place in Enhancing Learning in the Undergraduate Bioscience Teaching Laboratory?

    Science.gov (United States)

    Parry, Damian; Walsh, Cathy; Larsen, Carl; Hogan, Joanne

    2012-01-01

    Bioscience employers demand graduates with better practical competence. It is our supposition that, although undesirable, student learning is assessment driven and this is leading students to simply go through the motions in the practical setting (whether field work or laboratory based). In this intervention a Critical Incident Report was…

  16. Call for Papers--Bioscience Methods (ISSN 1925-1920)

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Bioscience Methods (BM) (ISSN 1925-1920) is a new launched, open access and peer-revi- ewed journal that dedicates to publish the original research papers involving in innovative technologies and novel experimental arts within the fields ofbiosciences.

  17. Call for papers—Bioscience Methods(ISSN 1925-1920)

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Bioscience Methods(BM)(ISSN 1925-1920) is a new launched,open access and peer-reviewed journal that dedicates to publish the original research papers involving in innovative technologies and novel experimental arts within the fields ofbiosciences.

  18. Call for papers--Bioscience Methods (ISSN 1925-1920)

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Bioscience Methods (BM) (ISSN 1925-1920) is a new launched, open access and peer-reviewed journal that dedicates to publish the original research papers involving in innovative technologies and novel experimental arts within the fields ofbiosciences.

  19. Scientific Grand Challenges: Discovery In Basic Energy Sciences: The Role of Computing at the Extreme Scale - August 13-15, 2009, Washington, D.C.

    Energy Technology Data Exchange (ETDEWEB)

    Galli, Giulia [Univ. of California, Davis, CA (United States). Workshop Chair; Dunning, Thom [Univ. of Illinois, Urbana, IL (United States). Workshop Chair

    2009-08-13

    The U.S. Department of Energy’s (DOE) Office of Basic Energy Sciences (BES) and Office of Advanced Scientific Computing Research (ASCR) workshop in August 2009 on extreme-scale computing provided a forum for more than 130 researchers to explore the needs and opportunities that will arise due to expected dramatic advances in computing power over the next decade. This scientific community firmly believes that the development of advanced theoretical tools within chemistry, physics, and materials science—combined with the development of efficient computational techniques and algorithms—has the potential to revolutionize the discovery process for materials and molecules with desirable properties. Doing so is necessary to meet the energy and environmental challenges of the 21st century as described in various DOE BES Basic Research Needs reports. Furthermore, computational modeling and simulation are a crucial complement to experimental studies, particularly when quantum mechanical processes controlling energy production, transformations, and storage are not directly observable and/or controllable. Many processes related to the Earth’s climate and subsurface need better modeling capabilities at the molecular level, which will be enabled by extreme-scale computing.

  20. Division of energy biosciences: Annual report and summaries of FY 1995 activities

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    The mission of the Division of Energy Biosciences is to support research that advances the fundamental knowledge necessary for the future development of biotechnologies related to the Department of Energy`s mission. The departmental civilian objectives include effective and efficient energy production, energy conservation, environmental restoration, and waste management. The Energy Biosciences program emphasizes research in the microbiological and plant sciences, as these understudied areas offer numerous scientific opportunities to dramatically influence environmentally sensible energy production and conservation. The research supported is focused on the basic mechanisms affecting plant productivity, conversion of biomass and other organic materials into fuels and chemicals by microbial systems, and the ability of biological systems to replace energy-intensive or pollutant-producing processes. The Division also addresses the increasing number of new opportunities arising at the interface of biology with other basic energy-related sciences such as biosynthesis of novel materials and the influence of soil organisms on geological processes.

  1. Highlights of the 3rd International Conference on High Pressure Bioscience and Biotechnology

    Directory of Open Access Journals (Sweden)

    J.A. Mignaco

    2005-08-01

    Full Text Available The 3rd International Conference on High Pressure Bioscience and Biotechnology was held in the city of Rio de Janeiro from September 27 to September 30, 2004. The meeting, promoted by the International Association of High Pressure Bioscience and Biotechnology (IAHPBB, congregated top scientists and researchers from all over the world. In common, they shared the use of hydrostatic pressure for research, technical development, or industrial applications. The meeting consisted of invited lectures, contributed papers and a well-attended poster session. Very exciting discussions were held inside and outside the sessions, and the goals of discussing state-of-the-art data and establishing working collaborations and co-operations were fully attained.

  2. Grand Challenges: Nanotechnology and the Social Studies

    Science.gov (United States)

    Manfra, Meghan McGlinn

    2013-01-01

    This article explores a multidisciplinary lesson on nanotechnology that can provide an effective means for teaching about both STEM and social studies topics. This approach encourages students to consider the "role that science and technology play in our lives and in our cultures." The extraordinary promise of nanotechnology, however, is…

  3. Aligning innovation with grand societal challenges

    DEFF Research Database (Denmark)

    Ricard, Lykke Margot

    2016-01-01

    This paper investigates the European Technology Platforms (ETPs) in wind power and in CO2 capture and storage supported by the European Commission (EC). It examines the role of these Platforms in shaping the trajectory of European energy technology policy, and shows that the EC’s support for the...

  4. Grand challenge in Biomaterials-wound healing.

    Science.gov (United States)

    Salamone, Joseph C; Salamone, Ann Beal; Swindle-Reilly, Katelyn; Leung, Kelly Xiaoyu-Chen; McMahon, Rebecca E

    2016-06-01

    Providing improved health care for wound, burn and surgical patients is a major goal for enhancing patient well-being, in addition to reducing the high cost of current health care treatment. The introduction of new and novel biomaterials and biomedical devices is anticipated to have a profound effect on the future improvement of many deleterious health issues. This publication will discuss the development of novel non-stinging liquid adhesive bandages in healthcare applications developed by Rochal Industries. The scientists/engineers at Rochal have participated in commercializing products in the field of ophthalmology, including rigid gas permeable contact lenses, soft hydrogel contact lenses, silicone hydrogel contact lenses, contact lens care solutions and cleaners, intraocular lens materials, intraocular controlled drug delivery, topical/intraocular anesthesia, and in the field of wound care, as non-stinging, spray-on liquid bandages to protect skin from moisture and body fluids and medical adhesive-related skin injuries. Current areas of entrepreneurial activity at Rochal Industries pertain to the development of new classes of biomaterials for wound healing, primarily in regard to microbial infection, chronic wound care, burn injuries and surgical procedures, with emphasis on innovation in product creation, which include cell-compatible substrates/scaffolds for wound healing, antimicrobial materials for opportunistic pathogens and biofilm reduction, necrotic wound debridement, scar remediation, treatment of diabetic ulcers, amelioration of pressure ulcers, amelioration of neuropathic pain and adjuvants for skin tissue substitutes. PMID:27047680

  5. Grand Challenges in Transportation and Transit Systems

    OpenAIRE

    Kaewunruen, Sakdirat; Sussman, Joseph M.; Matsumoto, Akira

    2016-01-01

    Transportation and transit systems draw upon broad spectra of research fields due to the diversity and interconnectivity of transport modes, including road, rail, aviation, pipeline, maritime, or even aerospace. These systems have evolved over centuries to be considerably more efficient and environment-friendly for a wide range of customers. The fundamental principle “safety first” is still the key priority in most research today. However, thanks to extensive interface with various customers;...

  6. Grand challenge in Biomaterials-wound healing

    OpenAIRE

    Salamone, Joseph C.; Salamone, Ann Beal; Swindle-Reilly, Katelyn; Leung, Kelly Xiaoyu-Chen; McMahon, Rebecca E.

    2016-01-01

    Providing improved health care for wound, burn and surgical patients is a major goal for enhancing patient well-being, in addition to reducing the high cost of current health care treatment. The introduction of new and novel biomaterials and biomedical devices is anticipated to have a profound effect on the future improvement of many deleterious health issues. This publication will discuss the development of novel non-stinging liquid adhesive bandages in healthcare applications developed by R...

  7. Grand Hotel prijutil hudozhnikov

    Index Scriptorium Estoniae

    2004-01-01

    Raadioajakirjanik Lea Veelmaa lindistas "Kunstikanali" 2004. a. esimese saate Grand Hotel Viljandis. Saatekülaliseks oli maalikunstnik Andres Tolts. Toltsi kaheksa akrüülmaali on eksponeeritud hotelli fuajees ja restoranis

  8. The molecular biology revolution and the rise of bioscience megacentres in North America and Europe

    OpenAIRE

    Philip Cooke

    2004-01-01

    This paper focuses on 'triple helix' effects in biosciences. Scientific change can have profound socioeconomic effects. The molecular biology revolution tilted pharmaceuticals production away from its fine chemistry path dependence into microbiology and biotechnology. The key to any triple helix effects has thus shifted to universities and spinouts buttressed with burgeoning public funding, leaving 'big pharma' increasingly playing the role of licenser and marketer of bought-in therapeutic tr...

  9. Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research †

    OpenAIRE

    Carol Kilkenny; Browne, William J.; Cuthill, Innes C; Michael Emerson; Altman, Douglas G.

    2014-01-01

    In the last decade the number of bioscience journals has increased enormously, with many filling specialised niches reflecting new disciplines and technologies. The emergence of open-access journals has revolutionised the publication process, maximising the availability of research data. Nevertheless, a wealth of evidence shows that across many areas, the reporting of biomedical research is often inadequate, leading to the view that even if the science is sound, in many cases the publications...

  10. The scientific assessment of combined effects of risk factors: different approaches in experimental biosciences and epidemiology

    OpenAIRE

    Boedeker, Wolfgang; Backhaus, Thomas

    2010-01-01

    Abstract The analysis of combined effects of substances or risk factors has been a subject to science for more than a century. With different goals, combined effect analysis was addressed in almost all experimental biosciences. The major theoretical foundation can be traced back to two distinct origins. First, to the work by the pharmacologist Loewe on the concept of concentration additivity and second to the biometrician Bliss and the concept of independent action. In the search f...

  11. Grand antiprism and quaternions

    International Nuclear Information System (INIS)

    Vertices of the four-dimensional (4D) semi-regular polytope, the grand antiprism and its symmetry group of order 400 are represented in terms of quaternions with unit norm. It follows from the icosian representation of the E8 root system which decomposes into two copies of the root system of H4. The symmetry of the grand antiprism is a maximal subgroup of the Coxeter group W(H4). It is the group Aut(H2 + H'2) which is constructed in terms of 20 quaternionic roots of the Coxeter diagram H2 + H'2. The root system of H4 represented by the binary icosahedral group I of order 120, constitutes the regular 4D polytope 600-cell. When its 20 quaternionic vertices corresponding to the roots of the diagram H2 + H'2 are removed from the vertices of the 600-cell the remaining 100 quaternions constitute the vertices of the grand antiprism. We give a detailed analysis of the construction of the cells of the grand antiprism in terms of quaternions. The dual polytope of the grand antiprism has also been constructed.

  12. Google Earth Grand Tour Themes

    Science.gov (United States)

    De Paor, D. G.; Whitmeyer, S. J.; Bentley, C.; Dordevic, M. M.

    2014-12-01

    As part of an NSF TUES Type 3 project entitled "Google Earth for Onsite and Distance Education (GEODE)," we are assembling a "Grand Tour" of locations on Earth and other terrestrial bodies that every geoscience student should know about and visit at least in virtual reality. Based on feedback from colleagues at previous meetings, we have identified nine Grand Tour themes: "Plates and Plumes," "Rocks and Regions," "Geology Through Time," "The Mapping Challenge*," "U.S. National Parks*," "The Magical Mystery Tour*," "Resources and Hazards," "Planets and Moons," and "Top of the Pops." Themes marked with an asterisk are most developed at this stage and will be demonstrated in real time. The Mapping Challenge invites students to trace geological contacts, measure bedding strike and dip and the plunge, trend, and facing of a fold. There is an advanced tool for modeling periclinal folds. The challenge is presented in a game-like format with an emphasis on puzzle-solving that will appeal to students regardless of gender. For the tour of U.S. national parks, we divided the most geologically important parks into four groups—Western Pacific, West Coast, Rockies, and East Coast. We are combining our own team's GigaPan imagery with imagery already available on the Internet. There is a great deal of imagery just waiting to be annotated for geological education purposes. The Magical Mystery Tour takes students to Google Streetview locations selected by instructors. Students are presented with questions or tasks and are given automatic feedback. Other themes are under development. Within each theme, we are crowd-sourcing contributions from colleagues and inviting colleagues to vote for or against proposed locations and student interactions. The GEODE team includes the authors and: Heather Almquist, Stephen Burgin, Cinzia Cervato, Gene Cooper, Paul Karabinos, Terry Pavlis, Jen Piatek, Bill Richards, Jeff Ryan, Ron Schott, Kristen St. John, and Barb Tewksbury.

  13. Division of Energy Biosciences annual report and summaries of FY 1996 activities

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-04-01

    The mission of the Division of Energy Biosciences is to support research that advances the fundamental knowledge necessary for the future development of biotechnologies related to the Department of Energy`s mission. The departmental civilian objectives include effective and efficient energy production, energy conservation, environmental restoration, and waste management. The Energy Biosciences program emphasizes research in the microbiological and plant sciences, as these understudied areas offer numerous scientific opportunities to dramatically influence environmentally sensible energy production and conservation. The research supported is focused on the basic mechanism affecting plant productivity, conversion of biomass and other organic materials into fuels and chemicals by microbial systems, and the ability of biological systems to replace energy-intensive or pollutant-producing processes. The Division also addresses the increasing number of new opportunities arising at the interface of biology with other basic energy-related sciences such as biosynthesis of novel materials and the influence of soil organisms on geological processes. This report gives summaries on 225 projects on photosynthesis, membrane or ion transport, plant metabolism and biosynthesis, carbohydrate metabolism lipid metabolism, plant growth and development, plant genetic regulation and genetic mechanisms, plant cell wall development, lignin-polysaccharide breakdown, nitrogen fixation and plant-microbial symbiosis, mechanism for plant adaptation, fermentative microbial metabolism, one and two carbon microbial metabolism, extremophilic microbes, microbial respiration, nutrition and metal metabolism, and materials biosynthesis.

  14. Ontologies and standards in bioscience research: for machine or for human

    Directory of Open Access Journals (Sweden)

    HuaiyuMi

    2011-02-01

    Full Text Available Ontologies and standards are very important parts of today’s bioscience research. With the rapid increase of biological knowledge, they provide mechanisms to better store and represent data in a controlled and structured way, so that scientists can share the data, and utilize a wide variety of software and tools to manage and analyze the data. Most of these standards are initially designed for computers to access large amounts of data that are difficult for human biologists to handle, and it is important to keep in mind that ultimately biologists are going to produce and interpret the data. While ontologies and standards must follow strict semantic rules that may not be familiar to biologists, effort must be spent to lower the learning barrier by involving biologists in the process of development, and by providing software and tool support. A standard will not succeed without support from the wider bioscience research community. Thus, it is crucial that these standards be designed not only for machines to read, but also to be scientifically accurate and intuitive to human biologists.

  15. Scientific Reports of Plasma Medicine and its Mechanism for Therapy in Plasma Bioscience Research Center

    Science.gov (United States)

    Choi, Eun Ha

    2015-09-01

    Scientific reports of plasma medicine and its basic mechanism for therapy will be introduced, especially, performed in Plasma Bioscience Research Center, Korea. We have investigated enhanced anticancer effect of monocytes and macrophages activated by nonthermal plasma which act as immune-modulator on these immune cells. Further, we investigated the action of the nanosecond pulsed plasma activated media (NPPAM) on the lung cancer cells and its DNA oxidation pathway. We observed OD induced apoptosis on melanocytes G361 cancer cells through DNA damage signaling cascade. We also studied DNA oxidation by extracting DNA from treated cancer cell and analyzed the effects of OD/OH/D2O2/H2O2 on protein modification and oxidation. Additionally, we attempted molecular docking approaches to check the action of D2O2 on the apoptosis related genes.

  16. Googling your genes: personal genomics and the discourse of citizen bioscience in the network age

    Directory of Open Access Journals (Sweden)

    Marina Levina

    2010-03-01

    Full Text Available In this essay, I argue that the rise of personal genomics is technologically, economically, and most importantly, discursively tied to the rise of network subjectivity, an imperative of which is an understanding of self as always already a subject in the network. I illustrate how personal genomics takes full advantage of social media technology and network subjectivity to advertise a new way of doing research that emphasizes collaboration between researchers and its members. Sharing one’s genetic information is considered to be an act of citizenship, precisely because it is good for the network. Here members are encouraged to think of themselves as dividuals, or nodes, in the network and their actions acquire value based on that imperative. Therefore, citizen bioscience is intricately tied, both in discourse and practices, to the growth of the network in the age of new media.

  17. A preliminary exploration of the advanced molecular bio-sciences research center

    International Nuclear Information System (INIS)

    Low dose and low dose rate radiation effects on lifespan, pathological changes, hemopoiesis and cytokine production in mice have been investigated in our laboratory. In the intermediate period of the investigation, an expert committee on radiation biology was organized. The purposes of the committee were to assess previous studies and advise on a future research plan for the Advanced Molecular Bio-Sciences Research Center (AMBIC). The committee emphasized the necessity of molecular research in radiation biology, and proposed the following five subjects: 1) molecular carcinogenesis by low dose radiation; 2) radiation effects on the immune and hemopoietic systems; 3) molecular mechanisms of hereditary effect; 4) noncancer diseases of low dose radiation, and 5) cellular mechanisms by low dose radiation. (author)

  18. Effect of A-Level Subject Choice and Entry Tariff on Final Degree and Level 1 Performance in Biosciences

    Science.gov (United States)

    King, Nicola C.; Aves, Stephen J.

    2012-01-01

    Following the publication of the higher education white paper increasing entry tariff and widening participation have become even more important issues for universities. This report examines the relationship between entry tariff and undergraduate achievement in Biosciences at the University of Exeter. We show that, whilst there is a significant…

  19. Production of Doctorates in the Biosciences, 1975-1980: An Experimental Forecast. Higher Education Panel Reports, No. 34.

    Science.gov (United States)

    Atelsek, Frank J.; Gomberg, Irene L.

    A survey was undertaken in 1976 to obtain short-term estimates of doctorate production directly from the heads of the science departments involved. These biosciences departments were surveyed in the 235 member institutions of the Higher Education Panel that grant doctorates: anatomy, biochemistry, biology, biometry/biostatistics/biomathematics,…

  20. Francis Crick, cross-worlds influencer: A narrative model to historicize big bioscience

    Science.gov (United States)

    Aicardi, Christine

    2016-01-01

    The essay is an empirical case study of famed British scientist Francis Crick. Viewing him as a ‘cross-worlds influencer’ who was moreover dedicated to a cause, I have tried to understand how these two characteristics influenced the trajectory of his long career and how they shaped his contributions to the diverse research fields in which he was active, and concluded that these characteristics reconfigure Crick's career into a coherent whole. First, I identify a major thread running through Crick's career: helping organise ‘un-disciplined’ new research fields, and show that his successive choices were not serendipitous but motivated by what he construed as a crusade against ‘vitalism’: anti-vitalism was a defining driver of his career. I then examine how Crick put his skills as a crossworlds influencer to the service of his cause, by helping organise his chosen fields of intervention. I argue that his activities as a cross-worlds influencer were an integral part of his way of ‘doing science’ and that his contributions to science, neuroscience in particular, should be re-evaluated in this light. This leads me to advance a possible strategy for historians to investigate big bioscience fields. Following Abir-Am, I propose to trace their genealogies back to the fluctuating semi-institutional gatherings and the institutional structures that sustained them. My research on Crick supports the view that such studies can bring insights into the question of why the contours of contemporary big bioscience endeavours have come to be shaped the way they are. Further, the essay provides a heuristic device for approaching these enquiries: ‘follow the cross-worlds influencers’ who worked to build and organise these semi-institutional gatherings and institutional structures. PMID:26383132

  1. Geo synthetics. a remarkable discipline with great achievements in the past and exciting challenges for a bright future; Geosinteticos: una importante disciplina con grandes logros en el pasado y emocionantes retos para un brillante futuro

    Energy Technology Data Exchange (ETDEWEB)

    Giroud, J. P.

    2014-02-01

    This paper presents achievements of the geo synthetics discipline and challenges facing the discipline. The paper shows that one of the main achievements of geo synthetics discipline and challenges facing the discipline. The paper shows that one of the main achievements of geo synthetics is that they have pervaded most branches of geotechnical engineering to the point where it is almost impossible to practice geotechnical engineering without geo synthetics. Then, the paper addresses the challenges facing the geo synthetics discipline. Two major types of challenges are identified: education challenges and technical challenges. Regarding technical challenges, it is recommended that researchers focus on behaviors that are not traditionally considered in geotechnical engineering in order to use geo synthetics to their full potential. Note: this is a significantly expanded version of the keynote paper presented at the 2008 GeoAmericas Conferences. (Author)

  2. Grand-Guignol

    OpenAIRE

    Desbois, Evelyne

    2007-01-01

    Le rire aux éclats, le mythe railleur, Brise des entonnoirs, l'Echo du Ravin ou n'importe quel autre journal du front rédigé dans les tranchées, fustigeaient les « bourreurs de crâne de l'arrière ». Dans le premier numéro du journal du front Le Crapouillot de 1917, Jean Galtier-Boissière dénonçait les « vampires » qui vivent du sang des combattants : « Et tandis que les bonshommes, couverts de boue, éclaboussés de sang, gravissent péniblement leur indescriptible calvaire, la "Grande Guerr......

  3. Grand unified theories. Pt. 2

    International Nuclear Information System (INIS)

    The author gives an introduction to the construction of grand unified theories on the base of the SU(3)xSU(2)xU(1) model of the strong, weak, and electromagnetic interactions. Especially he discusses the proton decay, neutrino masses and oscillations, and cosmological implications in connection with grand unified theories. (orig./HSI)

  4. La importancia de ser grande

    OpenAIRE

    Baisre, J. A.

    2007-01-01

    Se responde a las preguntas ¿por qué los mamíferos marinos son los animales más grandes del planeta?, ¿Por qué los peces no pueden ser más grandes?. Éstas y otras interrogantes son respondidas de forma sencilla y clara.

  5. Annual report and summaries of FY 1993 activities: Division of Energy Biosciences

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    The mission of the Energy Biosciences program is to generate fundamental information about plants and non-health related microorganisms that will constitute the base for new biotechnologies as well as supply information to improve usages of such organisms in their current form. The collective aims are totally consistent with the Department of Energy`s objectives of developing alternate energy sources, replacements for otherwise fossil energy derived products and providing critical fundamental information for the preservation and restoration of environmental conditions affected by energy related activities. The EB program takes full advantage of its organizational locale in the Office of Basic Energy Sciences to directly interact with such disciplines as Materials Sciences, Chemistry, Engineering and Geosciences to promote cross-disciplinary research and planning activities. One of the major specific objectives of the EB program is to probe the enormous capabilities of the specified organisms to carry out biochemical conversions. The limitation to realization of entirely new products and processes via biotechnology is the lack of basic understanding of natural processes. Such knowledge will then afford the advantage of developing procedures to the benefit of people and their society in providing new products along with providing new employment possibilities. This document consists of abstracts of projects supported in FY 1993.

  6. Division of Energy Biosciences annual report and summaries of FY 1991 activities

    Energy Technology Data Exchange (ETDEWEB)

    1991-09-01

    As a component of the Department of Energy, the Energy Biosciences (EB) program of the Office of Basic Energy Sciences supports long-term research aimed at addressing energy-related problems utilizing biological systems. There are three main components of the EB program. The first, Primary Biological Energy Conversion, concentrates on research on plant and microbial photosynthesis, but also deals with plant growth control, stress reactions, and interaction with pathogens. The second, Bioconversion of Products, concentrates on utilization of the products of primary energy conversion. Specific examples include biosynthesis of potential fuels or chemicals, biodegradation of lignocellulose into potentially useful compounds, plant/microbe symbiosis, microbial methanogenesis and fermentation. The third main component of the EB program involves providing the basic research infrastructure to support future discoveries. The emphasis here is on investigation of basic genetic mechanisms, both in novel systems and extensively studied systems such as maize; development of critical databases, techniques, and instrumentation; and support of training in areas that are important but underpopulated. Brief descriptions of currently supported research projects are provided. 186 refs., 1 tab (MHB)

  7. Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

    Directory of Open Access Journals (Sweden)

    Carol Kilkenny

    2014-02-01

    Full Text Available In the last decade the number of bioscience journals has increased enormously, with many filling specialised niches reflecting new disciplines and technologies. The emergence of open-access journals has revolutionised the publication process, maximising the availability of research data. Nevertheless, a wealth of evidence shows that across many areas, the reporting of biomedical research is often inadequate, leading to the view that even if the science is sound, in many cases the publications themselves are not “fit for purpose”, meaning that incomplete reporting of relevant information effectively renders many publications of limited value as instruments to inform policy or clinical and scientific practice [1–21]. A recent review of clinical research showed that there is considerable cumulative waste of financial resources at all stages of the research process, including as a result of publications that are unusable due to poor reporting [22]. It is unlikely that this issue is confined to clinical research [2–14,16–20].

  8. Division of Energy Biosciences annual report and summaries of FY 1991 activities

    International Nuclear Information System (INIS)

    As a component of the Department of Energy, the Energy Biosciences (EB) program of the Office of Basic Energy Sciences supports long-term research aimed at addressing energy-related problems utilizing biological systems. There are three main components of the EB program. The first, Primary Biological Energy Conversion, concentrates on research on plant and microbial photosynthesis, but also deals with plant growth control, stress reactions, and interaction with pathogens. The second, Bioconversion of Products, concentrates on utilization of the products of primary energy conversion. Specific examples include biosynthesis of potential fuels or chemicals, biodegradation of lignocellulose into potentially useful compounds, plant/microbe symbiosis, microbial methanogenesis and fermentation. The third main component of the EB program involves providing the basic research infrastructure to support future discoveries. The emphasis here is on investigation of basic genetic mechanisms, both in novel systems and extensively studied systems such as maize; development of critical databases, techniques, and instrumentation; and support of training in areas that are important but underpopulated. Brief descriptions of currently supported research projects are provided. 186 refs., 1 tab

  9. Warped Supersymmetric Grand Unification

    CERN Document Server

    Goldberger, W D; Smith, D R; Goldberger, Walter D.; Nomura, Yasunori; Smith, David R.

    2003-01-01

    We construct a realistic model of grand unification in AdS_5 truncated by branes, in which the unified gauge symmetry is broken by boundary conditions and the electroweak scale is generated by the AdS warp factor. We show that the model preserves the successful gauge coupling unification of the 4D MSSM at leading-logarithmic level. Kaluza-Klein towers, including those of XY gauge and colored Higgs multiplets, appear at the TeV scale, while the extra dimension provides natural mechanisms for doublet-triplet splitting and proton decay suppression. In one possible scenario supersymmetry is strongly broken on the TeV brane, in which case the lightest SU(3)_C x SU(2)_L x U(1)_Y gauginos are Dirac fermions, with universal masses at the weak scale, and the mass of the lightest XY gaugino is pushed well below that of the lowest gauge boson KK mode, improving the prospects for its production at the LHC. The bulk Lagrangian possesses a symmetry that we call GUT parity. If GUT parity is exact, the lightest GUT particle,...

  10. Grand slam on cancer.

    Science.gov (United States)

    Gartrell, Nanette

    2014-01-01

    A winner of 59 Grand Slam championships including a record 9 Wimbledon singles titles, Martina Navratilova is the most successful woman tennis player of the modern era. Martina was inducted into the International Tennis Hall of Fame, named "Tour Player of the Year" seven times by the Women's Tennis Association, declared "Female Athlete of the Year" by the Associated Press, and ranked one of the "Top Forty Athletes of All-Time" by Sports Illustrated. Equally accomplished off the court, Martina is an author, philanthropist, TV commentator, and activist who has dedicated her life to educating people about prejudice and stereotypes. After coming out as a lesbian in 1981, Martina became a tireless advocate of equal rights for lesbian, gay, bisexual, and transgender (LGBT) people, and she has contributed generously to the LGBT community. Martina is the author of seven books, including most recently Shape Your Self: My 6-Step Diet and Fitness Plan to Achieve the Best Shape of your Life, an inspiring guide to healthy living and personal fitness. Martina was diagnosed with breast cancer in 2010. PMID:24400624

  11. Diet type and challenge by Grande', 'Lucida Sans Unicode', sans-serif; font-size: 12px; ">Yersinia ruckeri influence the intestinal microbiota in rainbow trout (Grande', 'Lucida Sans Unicode', sans-serif; font-size: 12px; ">Oncorhynchus mykiss)

    DEFF Research Database (Denmark)

    Ingerslev, Hans Christian; Dalsgaard, Inger; Jørgensen, Louise von Gersdorff;

    ruckeri serotype O1 and intestines were then sampled 5 days post challenge for subsequent metagenomic examination based on the 16S rDNA gene. Next-generation sequencing was applied for the metagenomic studies using the Illumina HiSeq 2000 platform. Obtained sequences were paired, sorted, filtered, checked...

  12. Grand unified models and cosmology

    OpenAIRE

    Jeannerot, Rachel

    2006-01-01

    The cosmological consequences of particle physics grand unified theories (GUTs) are studied. Cosmological models are implemented in realistic particle physics models. Models consistent from both particle physics and cosmological considerations are selected. (...)

  13. The integration of the "spirituality in medicine" curriculum into the osteopathic communication curriculum at Kansas City University of Medicine and Biosciences.

    Science.gov (United States)

    Talley, Jan A; Magie, Richard

    2014-01-01

    With grant funding from the John Templeton Spirituality and Medicine Curricular Award to the George Washington Institute for Spirituality and Health, faculty at Kansas City University of Medicine and Biosciences (KCUMB) developed the "Spirituality in Medicine" curriculum. In developing the curriculum, faculty took into consideration competencies required by the Association of American Medical Colleges and qualitative results from surveys of medical school applicants and enrolled students. Strategies for curriculum delivery included lectures, panel discussions, role-playing, and training in the use of a spirituality assessment tool. A majority of the 250 students who received the training in 2010-2011 were able to demonstrate the following competencies: (1) being sensitive to patients' spiritual and cultural needs, (2) assessing patients' and their own spiritual needs, (3) appropriately using chaplain services for patient care, and (4) understanding the effects of health disparities and ethical issues on patient care. Challenges to implementation included a reduction in chaplain availability due to the economic downturn, a lack of student exposure to direct patient care during shadowing, too little religious diversity among chaplains, and changes in assignment schedules. New competencies required by the National Board of Osteopathic Medical Examiners overlap with and help ensure sustainability of the Spirituality in Medicine curriculum. KCUMB leaders have incorporated the use of the spirituality assessment tool into other parts of the curriculum and into service experiences, and they have introduced a new elective in palliative care. Synergistic efforts by faculty leaders for this initiative were critical to the implementation of this curriculum. PMID:24280841

  14. A business case for on-site generation: The BD biosciences pharmingen project

    Energy Technology Data Exchange (ETDEWEB)

    Firestone, Ryan; Creighton, Charles; Bailey, Owen; Marnay, Chris; Stadler, Michael

    2003-09-01

    Deregulation is haltingly changing the United States electricity markets. The resulting uncertainty and/or rising energy costs can be hedged by generating electricity on-site and other benefits, such as use of otherwise wasted heat, can be captured. The Public Utility Regulatory Policy Act (PURPA) of 1978 first invited relatively small-scale generators ({ge} 1 MW) into the electricity market. The advent of efficient and reliable small scale and renewable equipment has spurred an industry that has, in recent years, made even smaller (business scale) electricity generation an economically viable option for some consumers. On-site energy capture and/or conversion, known as distributed energy resources (DER), offers consumers many benefits, such as economic savings and price predictability, improved reliability, control over power quality, and emissions reductions. Despite these benefits, DER adoption can be a daunting move to a customer accustomed to simply paying a monthly utility bill. San Diego is in many ways an attractive location for DER development: It has high electricity prices typical of California and a moderate climate i.e. energy loads are consistent throughout the year. Additionally, the price shock to San Diego Gas and Electric (SDG&E) customers during the summer of 2000 has interested many in alternatives to electricity price vulnerability. This report examines the business case for DER at the San Diego biotechnology supply company, BD Biosciences Pharmingen, which considered DER for a building with 200-300 kW base-load, much of which accommodates the refrigerators required to maintain chemicals. Because of the Mediterranean climate of the San Diego area and the high rate of air changes required due to on-site use of chemicals, modest space heating is required throughout the year. Employees work in the building during normal weekday business hours, and daily peak loads are typically about 500 kW.

  15. 75 FR 37308 - Drawbridge Operation Regulations; Grand River, Grand Haven, MI

    Science.gov (United States)

    2010-06-29

    ... SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Grand River, Grand Haven, MI AGENCY....S. 31 Bridge at Mile 2.89 over the Grand River, at Grand Haven, MI. This deviation temporarily... of Grand Haven, MI, requested a temporary deviation from the current operating regulations set...

  16. Grand unification and before

    International Nuclear Information System (INIS)

    The standard SU(3)/sub c/ x SU(2)/sub L/ x U(1) model of strong and electroweak interactions contains the following parameters: (1) it has three indepenent couplings g3, g2 and g1. The QCD coupling g3 is often parameterized in terms of the mass scale Λ/sub MS/, while g2 and g1 are generally traded off for the electric charge e and the weak mixing angle theta/sub W/ via the relationships e2 = g22 sin2theta/sub W/ and tan2theta/sub W/ = 3g12/5g22; (2) there are two intermediate vector boson masses m/sub W/ and m/sub Z/ which are related by m/sub W/ = m/sub Z/cos theta/sub W/ and an arbitrary Higgs scalar mass m/sub phi/; (3) of its nine fermion masses m/sub e/, m/sub μ/, m/sub tau/, m/sub d/, m/sub s/, m/sub b/, m/sub u/, m/sub c/ and m/sub t/, all except, m/sub t/ have phenomenologically measured values. From e+e- annihilation PETRA data, one has the lower bound m/sub t/ greater than or equal to 18 GeV; (4) there are three quark mixing angles theta1, theta2, theta3 and a CP violating phase delta. In addition, there may be neutrino masses, lepton mixing angles, new generations of fermions, etc. As experimentalists measure these parameters with better precision, theorists seek natural relationships (such as m/sub W/ = m/sub Z/cos theta/sub W/) in an attempt to understand their origin. Such relationships are generally obtained by constraining the theory with additional symmetries. In that regard we now know how to correlate the three couplings g3, g2 and g1 through grand unification. Unfortunately, the origin of masses and their interrelationships are not as well understood. This problem of masses should be a signal that something fundamental is lacking in our present theories

  17. SBBN 2010: 7. Congress of the Brazilian Society of Nuclear Biosciences. Radiations in biosciences: advances and trends; SBBN 2010: 7. Congresso da Sociedade Brasileira de Biociencias Nucleares. Radiacoes em biociencias: avancos e perspectivas

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    Advance and new perspectives related to the use of ionizing and no ionizing radiations in nuclear biosciences are presented. Multidisciplinary approach, including radiopharmacy, radioprotection and dosimetry, cytogenetic, biosafety, radioecology, environmental toxicology are studied. Topics of Nuclear medicine, radiotherapy and image diagnosis, such as computerized tomography, PET scan, phantoms, biomedical radiography, are reported. Use of radioisotopes, evaluation of radiation dose rates, radiation dose distribution, radiation monitoring is considered. Environmental impact of radiation are also in human beings, animals and for several purposes are analyzed. (MAC)

  18. Anthropocene Age Wicked Challenges

    DEFF Research Database (Denmark)

    Edgeman, Rick; Wu, Zhaohui

    2015-01-01

    weather events, drought, and desertification; threatened food supplies; water pollution, air pollution, and soil contamination; and the connection of these to disease, violence, and terrorism. Wicked challenges are discussed in relation to enterprise excellence, sustainability, resilience and robustness......Grand global challenges, including wicked human caused or influenced ones key to sustainability, characterize the Anthropocene Age. Among these are climate change driven by increased methane and CO2 in the atmosphere; consequent global warming and increasing intensity and incidence of extreme...

  19. A tale of three next generation sequencing platforms: comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq sequencers

    Directory of Open Access Journals (Sweden)

    Quail Michael A

    2012-07-01

    Full Text Available Abstract Background Next generation sequencing (NGS technology has revolutionized genomic and genetic research. The pace of change in this area is rapid with three major new sequencing platforms having been released in 2011: Ion Torrent’s PGM, Pacific Biosciences’ RS and the Illumina MiSeq. Here we compare the results obtained with those platforms to the performance of the Illumina HiSeq, the current market leader. In order to compare these platforms, and get sufficient coverage depth to allow meaningful analysis, we have sequenced a set of 4 microbial genomes with mean GC content ranging from 19.3 to 67.7%. Together, these represent a comprehensive range of genome content. Here we report our analysis of that sequence data in terms of coverage distribution, bias, GC distribution, variant detection and accuracy. Results Sequence generated by Ion Torrent, MiSeq and Pacific Biosciences technologies displays near perfect coverage behaviour on GC-rich, neutral and moderately AT-rich genomes, but a profound bias was observed upon sequencing the extremely AT-rich genome of Plasmodium falciparum on the PGM, resulting in no coverage for approximately 30% of the genome. We analysed the ability to call variants from each platform and found that we could call slightly more variants from Ion Torrent data compared to MiSeq data, but at the expense of a higher false positive rate. Variant calling from Pacific Biosciences data was possible but higher coverage depth was required. Context specific errors were observed in both PGM and MiSeq data, but not in that from the Pacific Biosciences platform. Conclusions All three fast turnaround sequencers evaluated here were able to generate usable sequence. However there are key differences between the quality of that data and the applications it will support.

  20. Care for elderly : A challenge in the anaesthesia context

    OpenAIRE

    Larsson Mauleon, Annika

    2005-01-01

    Anaesthesia care involves bioscience and technical knowledge. Provision of anaesthesia care for elderly surgical patients can be a significant challenge when promoting patient comfort, safety, and satisfaction in a high-tech context with time constraints. Many patients in anaesthesia care are old and frail and have multiple illnesses and other problems, such as delicate skin, malnutrition, and pain. All this must be accounted for when caring for the elderly. Extra time in an...

  1. Software Engineering Support of the Third Round of Scientific Grand Challenge Investigations: An Earth Modeling System Software Framework Strawman Design that Integrates Cactus and UCLA/UCB Distributed Data Broker

    Science.gov (United States)

    Talbot, Bryan; Zhou, Shu-Jia; Higgins, Glenn

    2002-01-01

    One of the most significant challenges in large-scale climate modeling, as well as in high-performance computing in other scientific fields, is that of effectively integrating many software models from multiple contributors. A software framework facilitates the integration task. both in the development and runtime stages of the simulation. Effective software frameworks reduce the programming burden for the investigators, freeing them to focus more on the science and less on the parallel communication implementation, while maintaining high performance across numerous supercomputer and workstation architectures. This document proposes a strawman framework design for the climate community based on the integration of Cactus, from the relativistic physics community, and UCLA/UCB Distributed Data Broker (DDB) from the climate community. This design is the result of an extensive survey of climate models and frameworks in the climate community as well as frameworks from many other scientific communities. The design addresses fundamental development and runtime needs using Cactus, a framework with interfaces for FORTRAN and C-based languages, and high-performance model communication needs using DDB. This document also specifically explores object-oriented design issues in the context of climate modeling as well as climate modeling issues in terms of object-oriented design.

  2. Introduction to grand unification theories

    International Nuclear Information System (INIS)

    The Georgi-Glashow model is introduced based on the minimal gauge group SU(5) as a prototype grand unification theory of the electroweak and strong interactions. Simple estimation of sin2 theta/sub W/ in the symmetry limit and the renormalization corrections at the energy scale of M/sub W/ are given along with other successes of the SU(5) model

  3. Grand Unification without Proton Decay

    CERN Document Server

    Mütter, Andreas; Vaudrevange, Patrick K S

    2016-01-01

    It is commonly believed that grand unified theories (GUTs) predict proton decay. This is because the exchange of extra GUT gauge bosons gives rise to dimension 6 proton decay operators. We show that there exists a class of GUTs in which these operators are absent. Many string and supergravity models in the literature belong to this class.

  4. Designing a Virtual Grand Tour

    Science.gov (United States)

    Hansen, Per Skafte

    2004-01-01

    The Virtual Grand Tour (VGT) is a paradigm for integrating a presentation of an overview of a larger subject with the possibility of launching at any time an exploratory study of a given sub-topic. The name derives from the paradigm's emulation of those 18th-century travels intended to educate (especially) young, affluent British men; today, with…

  5. 78 FR 39998 - Safety Zone; Grand Haven 4th of July Fireworks; Grand River; Grand Haven, MI

    Science.gov (United States)

    2013-07-03

    ...-9826. SUPPLEMENTARY INFORMATION: Table of Acronyms DHS Department of Homeland Security FR Federal... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Grand Haven 4th of July Fireworks; Grand River; Grand Haven, MI AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast...

  6. 33 CFR 100.906 - Grand Haven Coast Guard Festival Waterski Show, Grand Haven, MI.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Grand Haven Coast Guard Festival Waterski Show, Grand Haven, MI. 100.906 Section 100.906 Navigation and Navigable Waters COAST GUARD... Grand Haven Coast Guard Festival Waterski Show, Grand Haven, MI. (a) Regulated Area. All waters of...

  7. Bioculture System: Expanding ISS Space Bioscience Capabilities for Fundamental Stem Cell Research and Commercial Applications

    Science.gov (United States)

    Blaber, Elizabeth; Dvorochkin, Natalya; Almeida, Eduardo; Fitzpatrick, Garret; Ellingson, Lance; Mitchell, Sarah; Yang, Anthony; Kosnik, Cristine; Rayl, Nicole; Cannon, Tom; Austin, Edward; Sato, Kevin

    With the recent call by the 2011 Decadal Report and the 2010 Space Biosciences Roadmap for the International Space Station (ISS) to be used as a National Laboratory for scientific research, there is now a need for new laboratory instruments on ISS to enable such research to occur. The Bioculture System supports the extended culturing of multiple cell types and microbiological specimens. It consists of a docking station that carries ten independent incubation units or ‘Cassettes’. Each Cassette contains a cooling chamber (5(°) C) for temperature sensitive solutions and samples, or long duration fluids and sample storage, as well as an incubation chamber (ambient up to 42(°) C). Each Cassette houses an independent fluidics system comprised of a biochamber, medical-grade fluid tubing, medium warming module, oxygenation module, fluid pump, and sixteen solenoid valves for automated biochamber injections of sampling. The Bioculture System provides the user with the ability to select the incubation temperature, fluid flow rate and automated biochamber sampling or injection events for each separate Cassette. Furthermore, the ISS crew can access the biochamber, media bag, and accessory bags on-orbit using the Microgravity Science Glovebox. The Bioculture System also permits initiation of cultures, subculturing, injection of compounds, and removal of samples for on-orbit processing using ISS facilities. The Bioculture System therefore provides a unique opportunity for the study of stem cells and other cell types in space. The first validation flight of the Bioculture System will be conducted on SpaceX5, consisting of 8 Cassettes and lasting for 30-37 days. During this flight we plan to culture two different mammalian cell types in bioreactors: a mouse osteocytic-like cell line, and human induced pluripotent stem cell (iPS)-derived cardiomyocytes. Specifically, the osteocytic line will enable the study of a type of cell that has been flown on the Bioculture System

  8. Results from KASCADE-Grande

    Energy Technology Data Exchange (ETDEWEB)

    Bertaina, M., E-mail: bertaina@to.infn.it [Dipartimento di Fisica Generale dell' Universita, Torino (Italy); Apel, W.D. [Institut fuer Kernphysik, KIT - Karlsruher Institut fuer Technologie (Germany); Arteaga-Velazquez, J.C. [Universidad Michoacana, Instituto de Fisica y Matematicas, Morelia (Mexico); Bekk, K. [Institut fuer Kernphysik, KIT - Karlsruher Institut fuer Technologie (Germany); Bluemer, J. [Institut fuer Kernphysik, KIT - Karlsruher Institut fuer Technologie (Germany); Institut fuer Experimentelle Kernphysik, KIT - Karlsruher Institut fuer Technologie (Germany); Bozdog, H. [Institut fuer Kernphysik, KIT - Karlsruher Institut fuer Technologie (Germany); Brancus, I.M. [National Institute of Physics and Nuclear Engineering, Bucharest (Romania); Buchholz, P. [Fachbereich Physik, Universitaet Siegen (Germany); Cantoni, E. [Dipartimento di Fisica Generale dell' Universita, Torino (Italy); Istituto di Fisica dello Spazio Interplanetario, INAF Torino (Italy); Chiavassa, A. [Dipartimento di Fisica Generale dell' Universita, Torino (Italy); Cossavella, F. [Institut fuer Experimentelle Kernphysik, KIT - Karlsruher Institut fuer Technologie (Germany); and others

    2012-11-11

    The KASCADE-Grande experiment, located at Karlsruhe Institute of Technology (Germany) is a multi-component extensive air-shower experiment devoted to the study of cosmic rays and their interactions at primary energies 10{sup 14}-10{sup 18} eV. Main goals of the experiment are the measurement of the all-particle energy spectrum and mass composition in the 10{sup 16}-10{sup 18} eV range by sampling charged (N{sub ch}) and muon (N{sub {mu}}) components of the air shower. The method to derive the energy spectrum and its uncertainties, as well as the implications of the obtained result, is discussed. An overview of the analyses performed by KASCADE-Grande to derive the mass composition of the measured high-energy comic rays is presented as well.

  9. Grand Challenges in Physics Education Research: Teacher Preparation

    Science.gov (United States)

    Heron, Paula

    2015-04-01

    The courses, curricula and programs that produce new K-12 teachers have been the subject of research in the physics education community for many years. In terms of recruitment, curricula, and mentoring, programs and pathways vary considerably from institution to institution. Each program addresses many different aspects of teaching including knowledge of the content and familiarity with best teaching practices. At the same time, even within physics (or physical science) there is a broad range of student outcomes that are considered important, including acquisition of factual knowledge, development of skill with disciplinary practices, and positive attitudes toward the discipline and one's own abilities. Given the broad range of both input and outcome variables it is no surprise that there are very few clear answers about the impact of teacher preparation on teachers, students and society. In this talk I will summarize some of the main findings to date, and identify some areas where much more research is needed.

  10. Facing the Grand Challenges through Heuristics and Mindfulness

    Science.gov (United States)

    Powietrzynska, Malgorzata; Tobin, Kenneth; Alexakos, Konstantinos

    2015-01-01

    We address the nature of mindfulness and its salience to education generally and to science education specifically. In a context of the historical embeddedness of mindfulness in Buddhism we discuss research in social neuroscience, presenting evidence for neuronal plasticity of the brain and six emotional styles, which are not biologically…

  11. Grand Challenge Portfolio: Driving Innovation in Industrial Energy Efficiency

    Energy Technology Data Exchange (ETDEWEB)

    None

    2011-01-04

    Under the Recovery Act, AMO provided cost-shared funding for early-stage, low-cost, "concept definition studies" of 47 promising innovations for next-generation manufacturing, energy-intensive processes, advanced materials, and greenhouse gas emissions reduction. The brochure provides information on each of these projects.

  12. The Grand Challenges and Myths of Neural-Symbolic Computation

    OpenAIRE

    Lamb, Luis C.

    2008-01-01

    The construction of computational cognitive models integrating the connectionist and symbolic paradigms of artificial intelligence is a standing research issue in the field. The combination of logic-based inference and connectionist learning systems may lead to the construction of semantically sound computational cognitive models in artificial intelligence, computer and cognitive sciences. Over the last decades, results regarding the computation and learning of classical reasoning within ...

  13. Science, technology and the 'grand challenge' of aging

    DEFF Research Database (Denmark)

    Jæger, Birgit; Peine, Alexander; Moors, Ellen;

    2015-01-01

    In this paper, we introduce the themes addressed and the approaches used in this special issue. We start by briefly discussing the state of the art in research and policy making related to science, technology and ageing. We argue that an important gap characterizes this state of the art: current ...... socio-material constitution of later life that implicates an important agenda for the future study of ageing and gerontechnology innovation....

  14. Security and Privacy Grand Challenges for the Internet of Things

    Energy Technology Data Exchange (ETDEWEB)

    Fink, Glenn A.; Zarzhitsky, Dimitri V.; Carroll, Thomas E.; Farquhar, Ethan D.

    2015-08-20

    Abstract— The growth of the Internet of Things (IoT) is driven by market pressures, and while security is being considered, the relationship between the unintended consequences of billions of such devices connecting to the Internet cannot be described with existing mathematical methods. The possibilities for illicit surveillance through lifestyle analysis, unauthorized access to information, and new attack vectors will continue to increase by 2020, when up-to 50 billion devices may be connected. This paper discusses various kinds of vulnerabilities that can be expected to arise, and presents a research agenda for mitigating the worst of the impacts. We hope to draw research attention to the potential dangers of IoT so that many of these problems can be avoided.

  15. Grand Challenges and Opportunities in Mathematics Education Research

    Science.gov (United States)

    Stephan, Michelle L.; Chval, Kathryn B.; Wanko, Jeffrey J.; Civil, Marta; Fish, Michael C.; Herbel-Eisenmann, Beth; Konold, Clifford; Wilkerson, Trena L.

    2015-01-01

    Mathematics education researchers seek answers to important questions that will ultimately result in the enhancement of mathematics teaching, learning, curriculum, and assessment, working toward ensuring that all students attain mathematics proficiency and increasing the numbers of students from all racial, ethnic, gender, and socioeconomic groups…

  16. Flexible Environments for Grand-Challenge Simulation in Climate Science

    Science.gov (United States)

    Pierrehumbert, R.; Tobis, M.; Lin, J.; Dieterich, C.; Caballero, R.

    2004-12-01

    Current climate models are monolithic codes, generally in Fortran, aimed at high-performance simulation of the modern climate. Though they adequately serve their designated purpose, they present major barriers to application in other problems. Tailoring them to paleoclimate of planetary simulations, for instance, takes months of work. Theoretical studies, where one may want to remove selected processes or break feedback loops, are similarly hindered. Further, current climate models are of little value in education, since the implementation of textbook concepts and equations in the code is obscured by technical detail. The Climate Systems Center at the University of Chicago seeks to overcome these limitations by bringing modern object-oriented design into the business of climate modeling. Our ultimate goal is to produce an end-to-end modeling environment capable of configuring anything from a simple single-column radiative-convective model to a full 3-D coupled climate model using a uniform, flexible interface. Technically, the modeling environment is implemented as a Python-based software component toolkit: key number-crunching procedures are implemented as discrete, compiled-language components 'glued' together and co-ordinated by Python, combining the high performance of compiled languages and the flexibility and extensibility of Python. We are incrementally working towards this final objective following a series of distinct, complementary lines. We will present an overview of these activities, including PyOM, a Python-based finite-difference ocean model allowing run-time selection of different Arakawa grids and physical parameterizations; CliMT, an atmospheric modeling toolkit providing a library of 'legacy' radiative, convective and dynamical modules which can be knitted into dynamical models, and PyCCSM, a version of NCAR's Community Climate System Model in which the coupler and run-control architecture are re-implemented in Python, augmenting its flexibility and adaptability.

  17. Single vesicle biochips for ultra-miniaturized nanoscale fluidics and single molecule bioscience

    DEFF Research Database (Denmark)

    Christensen, Andreas Lauge; Lohr, Christina; Christensen, Sune M.; Stamou, Dimitrios

    2013-01-01

    One of the major bottlenecks in the development of biochips is maintaining the structure and function of biomolecules when interfacing them with hard matter (glass, plastics, metals, etc.), a challenge that is exacerbated during miniaturization that inevitably increases the interface to volume ra...... high throughput, single vesicle biochips are still a niche technology that has yet to establish its commercial relevance....

  18. Status report on project GRAND

    CERN Document Server

    Poirier, J; Fidler, E; Gress, J; Herrera, M; Hemphill, P; Swartzendruber, C

    2008-01-01

    GRAND is an array of position sensitive proportional wire chambers (PWCs) located at 86.2 degrees W, 41.7 degrees N at an elevation of 220 m adjacent to the campus of the University of Notre Dame with 82 square meters of total muon detector area. The geometry of the PWCs allows the angles of the charged secondary muon tracks to be measured to +/- 0.3 deg in each of two orthogonal planes. Muons are 99% differentiated from electrons by means of a 51 mm steel plate in each detector.

  19. Graafikatriennaali grand prix Korea kunstnikule

    Index Scriptorium Estoniae

    1998-01-01

    Tallinna XI graafikatriennaali rahvusvaheline žürii andis grand prix korea kunstnikule Chung¡Sang-Gonile, kolm võrdset preemiat - soome kunstnikele Anita Jensenile ja Tapani Mikkonenile ning jaapani kunstnikule Estuko Obatale. Eesti Kunstimuuseumi preemia - Wendy Swallow. Tallinna linna preemia ja Ivar Luki sponsoripreemia - Walter Jule. Sponsoripreemiad : Paletti Eesti AS preemia - Inga Heamägi; Rannila Profiili preemia - Mojca Zlokarnik; UNDP preemia - Andrea Juan. Rotermanni soolalao arhitektuuri- ja kunstikeskuse diplom - Lis Ingram, Heli Päivikki Kurunsaari, Randi Strand, Wendy Swallow

  20. GRANDE SERTÃO: Cordilleras

    OpenAIRE

    Bairon Oswaldo Vélez Escallón

    2012-01-01

    Grande Sertão: Veredas (1956) y Pedro Páramo (1955) crean, en la misma instancia que interrumpen, figuraciones totalizadoras del ser y del mundo: así operan sus ficciones. Esa participación encuentra su máxima paradoja en la apropiación que, sobre esas obras, ha ejercido la crítica latinoamericana: como precursoras de obras posteriores o como consolidaciones de una literatura latinoamericana madura. ¿Esas obras aceptan sin tensiones o resistencias esa filiación? Este trabajo explora estos ...

  1. Standard grand unification from superstrings

    International Nuclear Information System (INIS)

    Recent developments about the construction of standard SO(10) and SU(5) grand unified theories from 4-dimensional superstrings are presented. Explicit techniques involving higher level affine Lie algebras, for obtaining such stringGUTs from symmetric orbifolds are discussed. Special emphasis is put on the different constraints and selection rules for model building in this string framework, trying to disentangle those which are generic from those depending on the orbifold construction proposed. Some phenomenological implications from such constraints are briefly discussed. (author). 14 refs, 2 tabs

  2. Grand Gauge-Higgs Unification

    CERN Document Server

    Kojima, Kentaro; Yamashita, Toshifumi

    2011-01-01

    We propose a novel way to break grand unified gauge symmetries via the Hosotani mechanism in models that can accommodate chiral fermions. Adjoint scalar fields are realized through the so-called diagonal embedding method which is often used in the heterotic string theory. We calculate the one-loop effective potential of the adjoint scalar field in a five dimensional model compactified on an S^1/Z_2 orbifold, as an illustration. It turns out that the potential is basically the same as the one in an S^1 model, and thus the results in literatures, in addition to the chiral fermions, can be realized easily.

  3. Supersymmetry and Supergravity: Phenomenology and Grand Unification

    OpenAIRE

    Arnowitt, R.; Nath, Pran

    1993-01-01

    A survey is given of supersymmetry and supergravity and their phenomenology. Some of the topics discussed are the basic ideas of global supersymmetry, the minimal supersymmetric Standard Model (MSSM) and its phenomenology, the basic ideas of local supersymmetry (supergravity), grand unification, supersymmetry breaking in supergravity grand unified models, radiative breaking of $SU(2) \\times U(1)$, proton decay, cosmological constraints, and predictions of supergravity grand unified models. Wh...

  4. Jurassic micropaleontology of the Grand Banks

    OpenAIRE

    Gradstein, F.

    2008-01-01

    Jurassic foraminifera in the marine deposits (up to 3km thick) of the Grand Banks of Newfoundland define eight biostratigraphic zones of Pliensbachian through Tithonian age. Jurassic marine deposition (~4cm/10k.y) kept pace with subsidence resulting in a relatively continuous, shallow marine sedimentation pattern. Central Grand Banks subsidence ceased in Late Jurassic time and the area became emergent with erosion taking place until Albian time. Grand Banks Jurassic foraminiferal assemblag...

  5. Engineering Improvement: Social and Historical Perspectives on the NAE’s “Grand Challenges”

    Directory of Open Access Journals (Sweden)

    Amy E. Slaton

    2012-11-01

    Full Text Available The list of engineering "Grand Challenges" lately developed by the National Academy of Engineering enters a long historical tradition of such epically scaled to-do lists, dating back to the profession's U.S. origins in the mid-19th century. The mission statements, codes of ethics, and, later, lists of so-called grand challenges that have issued from engineering societies have served the dual function of directing engineers' work and supporting particular cultural roles for these bodies of experts. Almost all such plans, regardless of period or sponsoring body, have also blended highly practical aims of industrial and infrastructural development with more inchoate projects of societal uplift. The Grand Challenges of the NAE, currently playing a formative role in many engineering organizations and research and teaching settings, extend this lineage, working from a selective and self-confirming view of human welfare. We might bring to the Grand Challenges the type of critical, politically informed analysis that historians and STS scholars have brought to other sites of engineering activity and professionalization, to detect the nature of interests that underlay all such projections of engineering’s role in society. Who is served by the development of different technologies, products, and infrastructures? Who might be harmed? Most fundamentally, the Grand Challenges proceed from the premise that engineering research, construction, invention, and production are to take precedence over their absence, as befits a body dedicated not to the contraction of such enterprises but to their extension. Yet the interests of sustainability, global health, and other areas of human well-being might be best served in certain cases by just such a turning away from engineering. Making explicit the social and historical assumptions of the NAE’s Grand Challenges, and probing the implications of those assumptions for a diverse range of actors and communities, may

  6. Flavor Symmetry and Grand Unification

    CERN Document Server

    Stech, Berthold

    2010-01-01

    The combination of flavor symmetries with grand unification is considered: GUT $ \\times$ flavor . To accommodate three generations the flavor group SO(3) is used. All fermions transform as 3-vectors under this group. The Yukawa couplings are obtained from vacuum expectation values of flavon fields. For the flavon fields (singlets with respect to the GUT group) and the Higgs fields (singlets with respect to the generation group) a simple form for the effective potentials is postulated. It automatically leads to spontaneous symmetry breaking for these scalar fields. Discrete S4 transformations relate the different locations of the minima of the potentials.These potentials can be used to describe the hierarchy of the well known up quark mass spectrum. Also the huge hierarchy of the masses of the Higgs fields in grand unified models can be parametrized in this way. It leads to a prediction of the mass of the lightest Higgs boson in terms of its vacuum expectation value $v_0$: $ m_{Higgs} = \\frac{v_0}{\\sqrt{2}} = ...

  7. Grand Junction Remedial Action Program

    International Nuclear Information System (INIS)

    The Grand Junction Remedial Action Program (hereinafter referred to as the Program) originated in 1972 due to a recognized need to reduce the levels of radiation found in some of the structures identified in Grand Junction, Colorado that were constructed in part with uranium mill tailings. Out of over 640 locations eventually identified as qualifying for corrective action, the Program performed remedial construction on 594 of them. The owners of over 45 unremediated structures either did not wish to participate in the voluntary Program, or the structures were torn down, burned down, or were abandoned before the Program could take action on them. Because this was the first remedial action program of its type, and because its task was to reduce the radiation levels as soon as practical, there was no time for lengthly research and development of remedial methods or techniques. Trial and error combined with basic engineering and health physics produced a Program that learned as it progressed. At a cost of $22.7 million over a 15-year period, a substantial portion of the community had radiation exposure reduced because many public buildings such as schools, churches, and businesses, as well as private residences were remediated. 21 refs., 10 figs., 6 tabs

  8. Proton decay: Numerical simulations confront grand unification

    International Nuclear Information System (INIS)

    The Grand Unified Theories of the electromagnetic, weak and strong interactions constitute a far reaching attempt to synthesize our knowledge of theoretical particle physics into a consistent and compelling whole. Unfortunately, many quantitative predictions of such unified theories are sensitive to the analytically intractible effects of the strong subnuclear theory (Quantum Chromodynamics or QCD). The consequence is that even ambitious experimental programs exploring weak and super-weak interaction effects often fail to give definitive theoretical tests. This paper describes large-scale calculations on a supercomputer which can help to overcome this gap between theoretical predictions and experimental results. Our focus here is on proton decay, though the methods described are useful for many weak processes. The basic algorithms for the numerical simulation of QCD are well known. We will discuss the advantages and challenges of applying these methods to weak transitions. The algorithms require a very large data base with regular data flow and are natural candidates for vectorization. Also, 32-bit floating point arithmetic is adequate. Thus they are most naturally approached using a supercomputer alone or in combination with a dedicated special purpose processor. (orig.)

  9. O grande teatro do mundo

    OpenAIRE

    Almeida, Ana

    2013-01-01

    A presente dissertação trata da análise cenográfica da peça O Grande Teatro do Mundo, de Calderón de la Barca, lavada à cena pelo CITAC, um grupo de teatro universitário, durante os anos 60. O pensamento cénico, não sendo ainda evidentemente expresso, encontrava-se englobado nas opções da encenação levada a cabo pelo argentino Victor Garcia, cujo trabalho se baseava numa arquitectura do espaço e numa permanente experimentação, privilegiando a procura de novas relações, tanto com a envolven...

  10. Grandes almacenes en Ginebra, Suiza

    Directory of Open Access Journals (Sweden)

    Braillard, P.

    1968-10-01

    Full Text Available This large building, whose metal structure is one of the most important ones erected in Switzerland, has 14 storeys. The sales zones occupy all the above ground floor levels, and the basements contain garages and stores. Additionally, there is a restaurant on the third floor, and administrative offices in the fourth floor of this outstanding commercial building, the «La Placette» Stores, of Geneva.Este gran edificio, cuya estructura metálica es una de las mayores construidas en Suiza, fue organizado en 14 niveles. Las plantas baja y superiores están destinadas a «venta»; y los sótanos, a garajes, almacenes, etc. La tercera planta alberga, además, el comedor, restaurante, etc.; y la cuarta, los locales de administración y dirección de este notable edificio comercial: «Grandes Almacenes La Placette», de Ginebra.

  11. Hyacinths Choke the Rio Grande

    Science.gov (United States)

    2002-01-01

    These images acquired by the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER), flying aboard NASA's Terra satellite, demonstrate the potential of satellite-based remote sensors to monitor infestations of non-native plant species. These images show the vigorous growth of water hyacinths along a stretch of the Rio Grande River in Texas. The infestation had grown so dense in some places it was impeding the flow of water and rendered the river impassible for boats. The hyacinth is an aquatic weed native to South America. The plant is exotic looking and, when it blooms, the hyacinth produces a pretty purple flower, which is why it was introduced into North America. However, it has the capacity to grow and spread at astonishing rates so that in the wild it can completely clog the flow of rivers and waterways in a matter of days or weeks. The top image was acquired on March 30, 2002, and the bottom image on May 9, 2002. In the near-infrared region of the spectrum, photosynthetically-active vegetation is highly reflective. Consequently, vegetation appears bright to the near-infrared sensors aboard ASTER; and water, which absorbs near-infrared radiation, appears dark. In these false-color images produced from the sensor data, healthy vegetation is shown as bright red while water is blue or black. Notice a water hyacinth infestation is already apparent on March 30 near the center of the image. By May 9, the hyacinth population has exploded to cover more than half the river in the scene. Satellite-based remote sensors can enable scientists to monitor large areas of infestation like this one rather quickly and efficiently, which is particularly useful for regions that are difficult to reach from on the ground. (For more details, click to read Showdown in the Rio Grande.) Images courtesy Terrametrics; Data provided by the ASTER Science Team

  12. La Grande: volver a empezar

    Directory of Open Access Journals (Sweden)

    Julio Premat

    2011-07-01

    Full Text Available Este texto, borrador de un trabajo más amplio, pretende despejar algunas pistas de lectura de La grande, en tanto que paradójico final de la producción de Saer. Digo “paradójico” porque puede tomársela como una novela de comienzo o de origen : de un volver a empezar, en todos los sentidos del término. En esa perspectiva podrían estudiarse algunos núcleos temáticos (como el retorno o el recuerdo de cara a la construcción del texto, a la relación planteada con la tradición y a la singular historia de su escritura (y al material genético que rodea y completa esta novela a la vez inacabada y póstuma. En esta intervención, la idea es la de comentar tres textos, escenas o frases del texto, y a partir de allí esbozar pistas para un estudio que está en ciernes.Première ébauche d’un travail de plus d’ampleur, ce texte vise à éclairer quelques pistes de lecture de La grande, en tant que fin paradoxale de la production de Saer. Je dis « paradoxale » parce que l’on peut considérer cette œuvre comme un roman des commencements ou des origines : comme un retour aux débuts, dans tous les sens du terme. Dans cette perspective, plusieurs nœuds thématiques (comme le retour ou le souvenir pourraient être étudiés en relation à la construction du texte, à la relation qui s’établit avec la tradition et à la singulière histoire de son écriture (et au matériau génétique qui entoure et complète ce roman, à la fois inachevé et posthume. Il sera question ici de commenter trois textes, scènes ou phrases du texte, et d’ébaucher à partir de là quelques pistes pour une étude à l’état naissant.The objective of this text, a draft for a broader work, is to outline some reading clues for La grande, inasmuch as it constitutes a paradoxical ending of Saer’s production. I say “paradoxical” because we can consider this work a novel of beginnings or of origins: a return to the beginning, in every meaning of the

  13. Supersymmetry and supergravity: Phenomenology and grand unification

    International Nuclear Information System (INIS)

    A survey is given of supersymmetry and supergravity and their phenomenology. Some of the topics discussed are the basic ideas of global supersymmetry, the minimal supersymmetric Standard Model (MSSM) and its phenomenology, the basic ideas of local supersymmetry (supergravity), grand unification, supersymmetry breaking in supergravity grand unified models, radiative breaking of SU(2) x U(1), proton decay, cosmological constraints, and predictions of supergravity grand unified models. While the number of detailed derivations are necessarily limited, a sufficient number of results are given so that a reader can get a working knowledge of this field

  14. Militari italiani e grande guerra

    Directory of Open Access Journals (Sweden)

    Emilio Franzina

    2015-01-01

    Full Text Available Il saggio verte su alcuni aspetti dei fenomeni immigratori che si collegano alla genesi e alla tenuta dei sensi di appartenenza etnica e nazionale. Accanto alla progressiva rimozione dei vecchi meccanismi di acculturazione linguistica, che scalzano, ove posseduto in partenza, l’italiano procurando la sua sostituzione progressiva –e in parte fisiologica– con il castigliano si assiste in America, per integrazione, anche al declino dell’“italianità politica”. Un momento di svolta prima del definitivo affermarsi di tale processo di “argentinizzazione” fu rappresentato però dalla congiuntura della grande guerra. Il suo deflagrare, infatti, coincise con il momento di massima espansione (non solo a Buenos Aires della presenza immigratoria straniera e di quella italiana in particolare. Diversamente da quanto succederà più tardi con il secondo conflitto mondiale, dopo quasi vent’anni però di declino o di arresto dei flussi in entrata, tra il 1914 e il 1918 si poté assistere infatti a una concreta forma di doppio patriottismo o di duplice lealtà politico-istituzionale da parte dei gruppi etnici immigratori all’interno dei quali si generarono scelte come la decisione presa da molti dei loro componenti di arruolarsi sotto le bandiere delle “antiche patrie” per raggiungere i campi di battaglia europei.

  15. Anatomy of grand unifying groups

    International Nuclear Information System (INIS)

    The Cartan-Dynkin theory of classical groups is considered with the aid of a lemma proposed in this work. The lemma says that all the Weyl conjugates of a dominant weight will have a common form with the dominant weight when they are expressed as linear combinations of fundamental representation weights (FRW) of the group. This reformulation of the Cartan-Dynkin theory simplifies the calculations concerning grand unifying schemes. Especially, the specification of the weights of a representation, the property of being real or complex, the branchings of a representation under its subgroups and the decomposition of a direct product are reduced to simple permutational calculations. We introduce the notion of ''modular decomposition'' to study the group representations. This work includes only the groups SU(N+1) because they have characteristics different from others, such as SO(2N+1), SP(2N), SO(2N) and exceptional groups. In the two successive applications the idea shall be completed also for these groups. (author)

  16. Grand partition function of hadronic bremsstrahlung

    International Nuclear Information System (INIS)

    The grand partition function of hadronic bremsstrahlung is obtained using saddle-point procedures. Several levels of approximation are considered. The results are qualitatively consistent with earlier simple approximations

  17. Rio Grande Channel, El Paso Area, 1852

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — Historical map of Rio Grande river between Texas and Mexico. U.S.-Mexican Boundary Survey.The original map is a Xerox of a Photolithographic Copy of Salazar...

  18. A Grand Gathering of Storytelling Artists

    Institute of Scientific and Technical Information of China (English)

    1998-01-01

    The grand storytelling fair held in Majie Township, Hebei Province every year, has a history of more than 400 years. ● Most of the stories used to be based on ancient legends and folk stories. Nowadays, there are also many newly-written pieces about people’s lives in modern times. ● Every year, the grand storytelling performance attracts hundreds and thousands of locals and visitors from several neigh-boring provinces.

  19. Programmable bio-nano-chip system: a flexible point-of-care platform for bioscience and clinical measurements.

    Science.gov (United States)

    McRae, Michael P; Simmons, Glennon W; Wong, Jorge; Shadfan, Basil; Gopalkrishnan, Sanjiv; Christodoulides, Nicolaos; McDevitt, John T

    2015-10-21

    The development of integrated instrumentation for universal bioassay systems serves as a key goal for the lab-on-a-chip community. The programmable bio-nano-chip (p-BNC) system is a versatile multiplexed and multiclass chemical- and bio-sensing system for bioscience and clinical measurements. The system is comprised of two main components, a disposable cartridge and a portable analyzer. The customizable single-use plastic cartridges, which now can be manufactured in high volumes using injection molding, are designed for analytical performance, ease of use, reproducibility, and low cost. These labcard devices implement high surface area nano-structured biomarker capture elements that enable high performance signaling and are index-matched to real-world biological specimens. This detection modality, along with the convenience of on-chip fluid storage in blisters and self-contained waste, represents a standard process to digitize biological signatures at the point-of-care. A companion portable analyzer prototype has been developed to integrate fluid motivation, optical detection, and automated data analysis, and it serves as the human interface for complete assay automation. In this report, we provide a systems-level perspective of the p-BNC universal biosensing platform with an emphasis on flow control, device integration, and automation. To demonstrate the flexibility of the p-BNC, we distinguish diseased and non-case patients across three significant disease applications: prostate cancer, ovarian cancer, and acute myocardial infarction. Progress towards developing a rapid 7 minute myoglobin assay is presented using the fully automated p-BNC system. PMID:26308851

  20. Tutorials in mathematical biosciences

    CERN Document Server

    2008-01-01

    The book offers an easy introduction to fast growing research areas in evolution of species, population genetics, ecological models, and population dynamics. The first two chapters review the concept and methodologies of phylogenetic trees; computational schemes and illustrations are given, including applications such as tracing the origin of SARS and influenza. The third chapter introduces the reader to ecological models, including predator-prey models. This chapter includes and introduction to reaction-diffusion equations, which are used to analyze the ecological models. The next chapter reviews a broad range of ongoing research in population dynamics, including evolution of dispersal models; it also features interesting mathematical theorems and lists open problems. The final chapter deals with gene frequencies under the action of migration and selection. The book is addressed to readers at the level of grad students and researchers. A background in PDEs is provided.

  1. Magnetic nanoparticles and biosciences

    Czech Academy of Sciences Publication Activity Database

    Šafařík, Ivo; Šafaříková, Miroslava

    New Delhi : Indian Society of Magnetic Fluid Research, 2003 - (Lal, K.), s. 171-173 [International Workshop on Recent Advances in Nanotechnology of Magnetic Fluids. New Delhi (IN), 22.01.2003-24.01.2003] R&D Projects: GA ČR(CZ) GA203/03/1070; GA MŠk(CZ) OC 523.80 Institutional research plan: CEZ:AV0Z6087904 Keywords : nanotechnology * magnetic fluid Subject RIV: JI - Composite Materials

  2. Reconstructing grand theory in Islamic human geography – Some preliminary notes

    Directory of Open Access Journals (Sweden)

    Amriah Buang

    2010-07-01

    Full Text Available To have or not to have a grand theory is the question asked and deliberated by contemporary geographers although some or many had already dismissed the legitimacy of the question altogether . This paper addresses the problem of grand theory in contemporary (Western human geography from an Islamic perspective. It is driven by the hypothesis that the de-legitimation or the debunking of an epistemological grand theory in contemporary human geography is neither absolute, nor final, nor universal. It is essentially a Western scholarship problem presented as if it is universal. It then proceeds to demonstrate how and why an epistemological grand theory is not a problem in the Islamic approach to knowledge. Recapitulating the gist of an earlier attempt, it provides a brief account of how an Islamic epistemology would grapple with three of the main issues and challenges facing a grand theory in human geography, namely, integrating the theoretical with the empirical, unifying multi-scalar analyses, and transcending the divide between the human and the natural sciences.

  3. Optics along the Rio Grande Research Corridor

    International Nuclear Information System (INIS)

    New Mexico's scientific, technological, and educational resources are concentrated along a 300-mile stretch of the Rio Grande, from Los Alamos in the north to the Las Cruces in the south. This area contains two major multidisciplinary national laboratories (Los Alamos and Sandia), three military R and D centers, three state universities, and numerous other technology-based organizations, including a growing number of ''high-tech'' businesses and industries. The state of New Mexico has initiated a program to develop these resources for economic growth through the establishment of the Rio Grande Research Corridor. Much of the future development along the Corridor will involve optics and optical technologies. This session of the Southwest Conference on Optics reviewed the various projects in the Rio Grande Research Corridor, focusing on applications of optics

  4. Status of the KASCADE-Grande Experiment

    CERN Document Server

    Kampert, K H

    2002-01-01

    The status and capabilities of the KASCADE-Grande extensive air shower experiment are presented. The installation is located at Forschungszentrum Karlsruhe and comprises a large collecting area (0.5 km^2) electromagnetic array (Grande) operated jointly with the existing KASCADE detectors. KASCADE-Grande will cover the primary energy range 10^16 eV < E_0 < 10^18 eV overlapping with KASCADE around 10^16 eV, thus providing continuous information on the primary energy and mass of cosmic rays from 3x10^14 eV up to 10^18 eV. The major goal of the measurements is the unambiguous observation of the``iron knee'' expected in the cosmic ray spectrum at E_k^{Fe} ~ 10^17 eV.

  5. A Grand Delta(96) x SU(5) Flavour Model

    CERN Document Server

    King, Stephen F; Stuart, Alexander J

    2012-01-01

    Recent results from the Daya Bay and RENO reactor experiments have measured the smallest lepton mixing angle and found it to have a value of theta_13 approximately 9 degrees. This result presents a new challenge for the existing paradigms of discrete flavour symmetries which attempt to describe all quark and lepton masses and mixing angles. Here we propose a Supersymmetric Grand Unified Theory of Flavour based on Delta(96) x SU(5), together with a U(1) x Z3 symmetry, including a full discussion of Delta(96) in a convenient basis. The Grand Delta(96) x SU(5) Flavour Model relates the quark mixing angles and masses in the form of the Gatto-Sartori-Tonin relation and realises the Georgi-Jarlskog mass relations between the charged leptons and down-type quarks. We predict a Bi-trimaximal (not Tri-bimaximal) form of neutrino mixing matrix, which, after including charged lepton corrections with zero phase, leads to the following GUT scale predictions for the atmospheric, solar, and reactor mixing angles: theta_23=36...

  6. Reisipakkumine - Grand Tour Itaalias / Mai Levin

    Index Scriptorium Estoniae

    Levin, Mai, 1942-

    2009-01-01

    Tiina Abeli koostatud ja Urmas Viigi kujundatud näitus "Grand Tour. Eesti kunstnikud Itaalias" Kumu Kunstimuuseumis 05. aprillini. Loetletud eksponeeritud tööde autoreid. Näitus annab ülevaate, kes siinsetest kunstnikest 19. sajandi algusest kuni 1930ndate aastateni Itaalias käisid ja kuidas see nende loomingut mõjutas

  7. Hilbert's Grand Hotel with a series twist

    Science.gov (United States)

    Wijeratne, Chanakya; Mamolo, Ami; Zazkis, Rina

    2014-08-01

    This paper presents a new twist on a familiar paradox, linking seemingly disparate ideas under one roof. Hilbert's Grand Hotel, a paradox which addresses infinite set comparisons is adapted and extended to incorporate ideas from calculus - namely infinite series. We present and resolve several variations, and invite the reader to explore his or her own variations.

  8. Old and new trends in grand unification

    International Nuclear Information System (INIS)

    In this paper a general review of Grand Unified Theories (GUT's) of forces and flavors is presented in a pedagogical way, with emphasis in the solution to the so called fermion mass hierarchy problem (mt/me ∼ 105). The authors review most of the models presented in the literature. A realistic model is presented at the end

  9. The Virtual Grand Tour as Educational Paradigm

    DEFF Research Database (Denmark)

    Hansen, Per Skafte; Mouritsen, Lars

    2001-01-01

    The Virtual Grand Tour as defined here bears some resemblance to its 18th century ancestor: a wide range of individual topics are treated as a whole; a tutor, whether real or simulated, present or remote, is provided; a set of problem solving tools forms an integrated part of the "traveller's" eq...

  10. Pathogenic Landscape of Transboundary Zoonotic Diseases in the Mexico–US Border Along the Rio Grande

    OpenAIRE

    Esteve-Gassent, Maria Dolores; Pérez de León, Adalberto A.; Romero-Salas, Dora; Feria-Arroyo, Teresa P; Patino, Ramiro; Castro-Arellano, Ivan; Gordillo-Pérez, Guadalupe; Auclair, Allan; Goolsby, John; Rodriguez-Vivas, Roger Ivan; Estrada-Franco, Jose Guillermo

    2014-01-01

    Transboundary zoonotic diseases, several of which are vector borne, can maintain a dynamic focus and have pathogens circulating in geographic regions encircling multiple geopolitical boundaries. Global change is intensifying transboundary problems, including the spatial variation of the risk and incidence of zoonotic diseases. The complexity of these challenges can be greater in areas where rivers delineate international boundaries and encompass transitions between ecozones. The Rio Grande se...

  11. Advantages of Computer Simulation in Enhancing Students' Learning about Landform Evolution: A Case Study Using the Grand Canyon

    Science.gov (United States)

    Luo, Wei; Pelletier, Jon; Duffin, Kirk; Ormand, Carol; Hung, Wei-chen; Shernoff, David J.; Zhai, Xiaoming; Iverson, Ellen; Whalley, Kyle; Gallaher, Courtney; Furness, Walter

    2016-01-01

    The long geological time needed for landform development and evolution poses a challenge for understanding and appreciating the processes involved. The Web-based Interactive Landform Simulation Model--Grand Canyon (WILSIM-GC, http://serc.carleton.edu/landform/) is an educational tool designed to help students better understand such processes,…

  12. The Grand Tack model: a critical review

    CERN Document Server

    Raymond, Sean N

    2014-01-01

    The `Grand Tack' model proposes that the inner Solar System was sculpted by the giant planets' orbital migration in the gaseous protoplanetary disk. Jupiter first migrated inward then Jupiter and Saturn migrated back outward together. If Jupiter's turnaround or "tack" point was at ~1.5 AU the inner disk of terrestrial building blocks would have been truncated at ~1 AU, naturally producing the terrestrial planets' masses and spacing. During the gas giants' migration the asteroid belt is severely depleted but repopulated by distinct planetesimal reservoirs that can be associated with the present-day S and C types. The giant planets' orbits are consistent with the later evolution of the outer Solar System. Here we confront common criticisms of the Grand Tack model. We show that some uncertainties remain regarding the Tack mechanism itself; the most critical unknown is the timing and rate of gas accretion onto Saturn and Jupiter. Current isotopic and compositional measurements of Solar System bodies -- including ...

  13. Between two evils: Investors prefer grand corruption!

    OpenAIRE

    Graf Lambsdorff, Johann

    2005-01-01

    Recent empirical studies claim that, in addition to levels of corruption, investors are deterred by its unpredictability. I claim instead that it is petty corruption that deters investors. I employ seven subcomponents of corruption for a sample of 102 countries that appear in the 2003 Global Competitiveness Report of the WEF. The second principal component of this data depicts a grand, political type, embracing corruption in government policymaking and in judicial decisions as opposed to corr...

  14. Implementation of ML Using Naïve Bayes Algorithm for Identifying Disease-Treatment Relation in Bio-Science Text

    Directory of Open Access Journals (Sweden)

    T.F. Michael Raj

    2013-01-01

    Full Text Available In recent years many successful machine learning applications have been developed, ranging from datamining programs to information-filtering systems that learn users' reading preferences. At the same time, there have been important advances in the theory and algorithms that can be used identify the diseases and treatment relations in a Bio-Science text. Imagine a computer learns from medical records which treatments are most effective for new diseases. Having the machine learning concept behind we have proposed a Machine Learning (ML approach based on Naïve Bayes (NB algorithm to improve the automatic disease identification in the medical field. And also we have improved text classification by using an integrated model.

  15. Development of a dedicated beam forming system for material and bioscience research with high intensity, small field electron beam of LILLYPUT 3 accelerator at Wroclaw Technology Park

    CERN Document Server

    Adrich, Przemysław; Wilk, Piotr; Chorowski, Maciej; Poliński, Jarosław; Bogdan, Piotr

    2016-01-01

    The primary use of the LILLYPUT 3 accelerator at the Nondestructive Testing Laboratory at Wroclaw Technology Park is X-ray radiography for nondestructive testing, including R&D of novel techniques for industrial and medical imaging. The scope of possible applications could be greatly extended by providing a system for irradiation with electron beam. The purpose of this work was to design such a system, especially for high dose rate, small field irradiations under cryogenic conditions for material and bioscience research. In this work, two possible solutions, based either on beam scanning or scattering and collimation, were studied and compared. It was found that under existing conditions efficiency of both systems would be comparable. The latter one was adopted due to its simplicity and much lower cost. The system design was optimized by means of detailed Monte Carlo modeling. The system is being currently fabricated at National Centre for Nuclear Research in \\'Swierk.

  16. Raptor Use of the Rio Grande Gorge

    Energy Technology Data Exchange (ETDEWEB)

    Ponton, David A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-03-20

    The Rio Grande Gorge is a 115 km long river canyon located in Southern Colorado (15 km) and Northern New Mexico (100 km). The majority of the canyon is under the administration of the Bureau of Land Management {BLM), and 77 km of the canyon south of the Colorado/New Mexico border are designated Wild River under the National Wild and Scenic Rivers Act of 1968. Visits I have made to the Rio Grande Gorge over the past 15 .years disclosed some raptor utilization. As the Snake River Birds of Prey Natural Area gained publicity, its similarity to the Rio Grande Gorge became obvious, and I was intrigued by the possibility of a high raptor nesting density in the Gorge. A survey in 1979 of 20 km of the northern end of the canyon revealed a moderately high density of red-tailed hawks and prairie falcons. With the encouragement of that partial survey, and a need to assess the impact of river-running on nesting birds of prey, I made a more comprehensive survey in 1980. The results of my surveys, along with those of a 1978 helicopter survey by the BLM, are presented in this report, as well as general characterization of the area, winter use by raptors, and an assessment of factors influencing the raptor population.

  17. Dans le grand collisionneur du CERN

    CERN Document Server

    Campanelli, Mario

    2014-01-01

    Ce livre fait pénétrer le lecteur non initié dans l’instrument scientifique le plus grand du monde. D’ailleurs, le web fut précisément inventé à Genève en vue d’une collaboration aussi gigantesque. Résultat de vingt ans de recherche, le LHC, Grand collisionneur de hadrons, est l’anneau de 26,7 km creusé sous la frontière francosuisse, où sont accélérés, en sens opposés, des paquets de particules jusqu’à des vitesses et des énergies extrêmes. Ainsi la physique s’est-elle engagée dans une étape nouvelle de nos connaissances. Après les grandes découvertes de l’univers et de la réalité microscopique du siècle dernier, le collisionneur nous fait progresser aujourd’hui dans un «nuage de probabilités» aux frontières de l’antimatière. Dans une bousculade de particules, voici le champ convoité du boson de Higgs. Mario Campanelli, professeur associé à l’Université de Londres et collaborateur au projet ATLAS du LHC, propose, dans cet ouvrage, de s’introduire pas �...

  18. Proton decay in grand unified theories

    International Nuclear Information System (INIS)

    Interactions which violate the conservation of baryon and lepton number represent an intrinsic part of all grand unified theories (GUTs) of strong and electroweak interactions. These new interactions - predicted within the framework of GUTs - generate B and L violating four-fermion interactions via the exchange of superheavy particles which cannot be ascribed a well-defined baryon or lepton number. The effective coupling constant of these four-fermion interactions might be large enough to make the proton decay detectable by the present generation of experiments. In this review the basic concepts of conventional as well as supersymmetric GUTs relevant for proton decay are sketched. The baryon number violating sector of grand unified theories is discussed in more detail. Special emphasis is laid on the various selection rules arising as consequences of low-energy gauge invariance and supersymmetry for proton decay. These selection rules already determine the coarse pattern of the resulting decay modes and branching ratios without any reference to or detailed knowledge of the underlying grand unified theory. Finally the numerous theoretical predictions are summarized and confronted with experiment. (Author)

  19. [Grand Banks activity : updates and opportunities

    International Nuclear Information System (INIS)

    An overview of the exploration and on-going activities by the petroleum industry on the Grand Banks of Newfoundland was presented. The two offshore oil developments underway are Hibernia and Terra Nova, both located in the Jeanne d'Arc Basin. Current production from Hibernia is 68,000 bopd, expected to rise to 130,000 bopd in 1999. The Terra Nova Field is still under development. Total recoverable reserves from the 17 discoveries made in the Jeanne d'Arc Basin are estimated at 1.6 billion barrels of oil and 4 trillion cubic feet of gas. Industry participants in the area include Amoco, Petro-Canada, Mobil, Chevron, Husky and Norsk Hydro. Petro-Canada believes the Grand Banks represent one of the best opportunities for oil anywhere in the world. There are currently 21 exploration licenses held on the Grand Banks. Major attractions of the area include the large reserve potential, the relatively low finding costs, the size of the pools being discovered, improvements in offshore technology that have substantially lowered development costs, and a profit-sensitive generic royalty regime that ensures reasonable rates of return for investors. figs

  20. Needs assessment for the Greenway Grand Forks-East Grand Forks development and public education

    Science.gov (United States)

    Munski, Laura

    Following the flood of 1997, the U.S. Army Corps of Engineers included the Greenway Grand Forks---East Grand Forks (the Greenway) as a flood control measure for Grand Forks, North Dakota and East Grand Forks, Minnesota. It extends along both the Red River of the North and the Red Lake River, encompassing 2200 acres of land. The cities of Grand Forks and East Grand Forks hired consultants to assist with the postflood planning process. The planning process culminated with the Red River of the North Greenway Final Report (Flink, 1998). The purpose of this study was to determine if the development of the Greenway addressed the objectives of the planning report. The history of the land adjacent to the rivers was reviewed to document the progression of riverfront development. Anecdotal evidence was collected, field observations were made, city council minutes were reviewed, Greenway Technical Committee members were interviewed, Greenway Technical Committee minutes were reviewed, and the Greenway Grand Forks---East Grand Forks survey results were reviewed to determine if the objectives of the Red River of the North Greenway Final Report were addressed. A cross section survey was designed by Laura Munski for this dissertation research. The survey was approved by the Greenway Technical Committee. The survey collected both quantitative and qualitative data from the community. The purpose of the survey portion of the research project was to ascertain how residents were kept informed of activities on the Greenway and what amenities residents were using on the Greenway and to solicit their comments regarding the Greenway. The results of the survey research were used in both marketing and event planning for the Greenway. The singular qualitative survey question gave respondents an opportunity to share their comments regarding the Greenway. The qualitative data analysis provided insight to the amenities and educational programs desired by respondents, their concerns regarding the

  1. Grandes hitos de la historia de la novela euroamericana (El siglo XIX: los grandes maestros).

    OpenAIRE

    Bravo Castillo, Juan

    2010-01-01

    Con este segundo volumen de Grandes hitos de la historia de la novela euroamericana. El siglo XIX: Los grandes maestros, he proseguido lo que desde un principio pretendí que fuera un vasto recorrido por la novelística tanto de Europa como de América, siguiendo los parámetros del canon occidental, desde los orígenes del género hasta nuestros días. Nacida a partir de un proyecto I+D con el objetivo de colmar una laguna existente en España, donde los estudios de Historia Literaria cada vez andan...

  2. Fauna reptiliana do norte da grande Porto Alegre, Rio Grande do Sul, Brasil

    OpenAIRE

    Thales de Lema; Marisa Ibarra Vieira; Moema Leitão de Araújo

    1983-01-01

    This paper reports the preliminary results of two years of herpetogeographic studies in the region called «Grande Porto Alegre» at its northern portion. The physiognomy shows, at North, slopes of the Brazilian Southern Plateau, more or less forested in a general view; these elevations graãuálly decrease to the South until the levei of the sea to Atlantic littoral by the eastern border, and to Rio Grande do Sul savanah, which extends to Uruguay and Argentina. The biota is transitio...

  3. Maternal and fetal outcome in grand multipara

    International Nuclear Information System (INIS)

    Study Design: Case control study. Place and Duration of Study: Gynecology and Obstetric Unit-I of the Jinnah Post Graduate and Medical Centre Karachi, from February 2009 to January 2010. Patients and Methods: One hundred (100) patients of grand multipara (GMP), (parity = 5) and 100 patients of multipara (MP) (parity 2-4) were included in the study. Pregnant women with known medical conditions including essential hypertension, diabetes mellitus, epilepsy, primigravidas, women with previous caesarean section and twin pregnancies were excluded. Patients were admitted through antenatal clinic and emergency. A detailed history was taken and a physical examination was done with special emphasis on obstetrical examination. Investigations like blood CP, Urine D/R, blood grouping and sonogram were done. During labour, mother and neonates were managed according to ward protocols. Maternal and fetal outcomes were compared among GMPs and MPs. Results: A high frequency of anaemia (81% vs 20%), pregnancy induced hypertension (45%, vs. 26%) and gestational diabetes (9%, vs1%) were seen in GMP as compared to MP group. Frequency of malpresentations (26% vs 15%), postpartum hemorrhage (15%, vs 10%) and intrauterine deaths (26%, vs 13%) were higher in GMP group along with a high caesarean delivery rate (GMP 21%, MP 14%). A higher maternal mortality (GMP 4%, MP 1%) and low APGAR score (GMP 12%, MP 4%) were observed among babies born to grand multipara group. Conclusion: Grand multiparity is associated with adverse outcome for both mother and fetus. Effort should be directed to reduce high parity in the community through effective family planning initiatives. Specialized antenatal and obstetrical care facilities should be available. (author)

  4. Grand Banquet of CDM for Power Enterprises

    Institute of Scientific and Technical Information of China (English)

    Peng Yuanchang; Jin Wen

    2007-01-01

    @@ The Kyoto Protocol was taken into effect on Feb. 16, 2005. It requires developed countries to reduce their greenhouse gas emissions, but it doesn't set binding limits on developing countries, such as China. The developed countries found that it is more cost-effective to reduce the emissions in developing countries than in their own. Therefore, the CDM emerged as the times require. Due to unfamiliarity and complicatedness, Chinese enterprises had been hesitating and taking wait-and-see attitude toward CDM, but they couldn't resist the attraction of free dinner of CDM, more and more enterprises started to attend the grand banquet of CDM since 2006.

  5. SLAM contraint en environnement de grande taille

    OpenAIRE

    Ramadasan, Datta; Chevaldonné, Marc; Chateau, Thierry

    2014-01-01

    National audience Ce papier présente un algorithme de localisation et cartographie simultanée (ou SLAM pour Simultaneous Localization And Mapping) utilisant des contraintes issues d'un modèle d'environnement, on parle alors de SLAM contraint. L'objectif est d'utiliser un modèle 3D épars de grande taille issu d'une reconstruction de type SFM (Structure From Motion) afin d'estimer le mouvement de la caméra relativement au modèle, même lorsque ce dernier est peu ou pas observé. Il est nécesai...

  6. Grand-mother clocks and quiet lasers

    OpenAIRE

    Arnaud, Jacques; Chusseau, Laurent; Philippe, Fabrice

    2009-01-01

    7 pages Galileo noted in the 16th century that the period of oscillation of a pendulum is almost independent of the amplitude. However, such a pendulum is damped by air friction. The latter may be viewed as resulting from air molecules getting in contact with the pendulum. It follows that air friction, not only damps the oscillation, but also introduces randomness. In the so-called ``grand-mother'' clock, discovered by Huygens in the 18th century, damping is compensated for, on the average...

  7. FOCAL Grande Utopia EM音箱

    Institute of Scientific and Technical Information of China (English)

    成师

    2008-01-01

    对于一个真正在音响领域有所追求的品牌来讲,创新与改进是没有尽头的。尽管愈往前发展,技术的突破度会越来越小,但这仍不妨碍品牌向着高境界的持续前行。近期,法国劲浪(FOCAL)最新发表的Grande Utopia EM音箱,便是展示其研发成果的生动例证。

  8. The periodicity of Grand Solar Minimum

    Science.gov (United States)

    Velasco Herrera, Victor Manuel

    2016-07-01

    The sunspot number is the most used index to quantify the solar activity. Nevertheless, the sunspot is a syn- thetic index and not a physical index. Therefore, we should be careful to use the sunspot number to quantify the low (high) solar activity. One of the major problems of using sunspot to quantify solar activity is that its minimum value is zero. This zero value hinders the reconstruction of the solar cycle during the Maunder minimum. All solar indexes can be used as analog signals, which can be easily converted into digital signals. In con- trast, the conversion of a digital signal into an analog signal is not in general a simple task. The sunspot number during the Maunder minimum can be studied as a digital signal of the solar activity In 1894, Maunder published a discovery that has maintained the Solar Physics in an impasse. In his fa- mous work on "A Prolonged Sunspot Minimum" Maunder wrote: "The sequence of maximum and minimum has, in fact, been unfailing during the present century [..] and yet there [..], the ordinary solar cycle was once interrupted, and one long period of almost unbroken quiescence prevailed". The search of new historical Grand solar minima has been one of the most important questions in Solar Physics. However, the possibility of estimating a new Grand solar minimum is even more valuable. Since solar activity is the result of electromagnetic processes; we propose to employ the power to quantify solar activity: this is a fundamental physics concept in electrodynamics. Total Solar Irradiance is the primary energy source of the Earth's climate system and therefore its variations can contribute to natural climate change. In this work, we propose to consider the fluctuations in the power of the Total Solar Irradiance as a physical measure of the energy released by the solar dynamo, which contributes to understanding the nature of "profound solar magnetic field in calm". Using a new reconstruction of the Total Solar Irradiance we found the

  9. High resolution magnetic spectrograph 'Grand Raiden'

    International Nuclear Information System (INIS)

    In the report of the last 1988, the basic design of a new high resolution (p/Δp = 37750) magnetic spectrograph of the type QSQDMD (+D), named 'Grand Raiden', was presented. Here, we show results of more detailed ray-tracing calculations; the focal line property, the image aberration, and the compensation of the kinematic broadening by multipole fields. The final design of the new DSR (dipole for spin rotation) for the measurement of in-plane spin observables are also reported. (author)

  10. Lie groups and grand unified theories

    International Nuclear Information System (INIS)

    This work presents some concepts in group theory and Lie algebras and, at same time, shows a method to study and work with semisimple Lie groups, based on Dynkin diagrams. The aproach taken is not completely formal, but it presents the main points of the elaboration of the method, so its mathematical basis is designed with the purpose of making the reading not so cumbersome to those who are interested only in a general picture of the method and its usefulness. At the end it is shown a brief review of gauge theories and two grand-unification models based on SO(13) and E7 gauge groups. (author)

  11. Economic impact of alternative policy responses to prolonged and severe drought in the Rio Grande Basin

    Science.gov (United States)

    Booker, James F.; Michelsen, Ari M.; Ward, Frank A.

    2005-02-01

    In the Rio Grande Basin, water is overallocated, demands are growing, and river flows and uses are vulnerable to drought and climate change. Currently, the basin is in the third year of severe drought; irrigation and municipal water diversions have been severely curtailed; extensive diversions threaten endangered species, and reservoir volumes are nearly depleted. A central challenge is development of policies that efficiently and equitably allocate the basin's water resources among competing uses across political and institutional jurisdictions. A basin-wide, nonlinear programming model optimizes resource allocations and water use levels for the upper part of the Rio Grande Basin to test whether institutional adjustments can reduce damages caused by drought. Compared to existing institutions, we find that future drought damages could be reduced by 20 and 33% per year through intracompact and interstate water markets, respectively, that would allow water transfers across water management jurisdictions. Results reveal economic tradeoffs among water uses, regions, and drought control strategies.

  12. The Grand Duchy on the Grand Tour: A Historical Study of Student Migration in Luxembourg

    Science.gov (United States)

    Rohstock, Anne; Schreiber, Catherina

    2013-01-01

    Since Luxembourg became independent in 1839, practically the entire political, economic and intellectual elite of the country has been socialised abroad. It was only in 2003 that the Grand Duchy set up its own university; before then, young Luxembourgers had to study in foreign countries. Over the past 150 years, Luxembourg has thus experienced…

  13. SUGRA Grand Unification, LHC and Dark Matter

    CERN Document Server

    Nath, Pran

    2012-01-01

    A brief review is given of recent developments related to the Higgs signal and its implications for supersymmetry in the supergravity grand unification framework. The Higgs data indicates that the allowed parameter space largely lies on focal curves and focal surfaces of the Hyperbolic Branch of radiative breaking of the electroweak symmetry where TeV size scalars naturally arise. The high mass of the Higgs leads to a more precise prediction for the allowed range of the spin independent neutralino -proton cross section which is encouraging for the detection of dark matter in future experiments with greater sensitivity. Also discussed is the status of grand unification and a natural solution to breaking the GUT group at one scale and resolving the doublet-triplet problem. It is shown that the cosmic coincidence can be compatible within a supersymmetric framework in a muticomponent dark matter picture with one component charged under $B-L$ while the other component is the conventional supersymmetric dark matter...

  14. Aquatic macroinvertebrates of the Grand Calumet River

    Science.gov (United States)

    Last, Laurel L.; Whitman, Richard L.

    2000-01-01

    The Grand Calumet River is potential habitat for a rich community of aquatic macroinvertebrates. Historical surveys of these organisms have been limited to post-industrialization of the Calumet Region; but because river habitats and conditions prior to industrialization have been described, past macroinvertebrate composition can be inferred. In the past 20 years, several surveys have been conducted in the Grand Calumet that have focused on a limited area, but when these studies are amassed the information available covers much of the river. In this paper, the aquatic macroinvertebrate communities in the river are described, and options for restoration are discussed. Many of the macroinvertebrates present are indicators of high levels of pollution, but a few pollution-sensitive species have been found. There is evidence, however, that the sediment quality has improved since the 1960's, likely due to pollution controls that have been put into place. Restoration opportunities should consider the macroinvertebrate community and the potential to improve sediment habitat without damaging the community structure.

  15. Neutrino mass and grand unification of flavor

    CERN Document Server

    Mohapatra, Rabindra N

    2010-01-01

    The problem of understanding quark mass and mixing hierarchies has been an outstanding problem of particle physics for a long time. The discovery of neutrino masses in the past decade, exhibiting mixing and mass patterns so very different from the quark sector has added an extra dimension to this puzzle. This is specially difficult to understand within the framework of conventional grand unified theories which are supposed to unify the quarks and leptons at short distance scales. In the paper, I discuss a recent proposal by Dutta, Mimura and this author that appears to provide a promising way to resolve this puzzle. After stating the ansatz, we show how it can be realized within a SO(10) grand unification framework. Just as Gell-Mann's suggestion of SU(3) symmetry as a way to understand the hadronic flavor puzzle of the sixties led to the foundation of modern particle physics, one could hope that a satisfactory resolution of the current quark-lepton flavor problem would provide fundamental insight into the na...

  16. Preface to a GUT (Grand Unified Theory)

    International Nuclear Information System (INIS)

    A Grand Unified Theory (GUT) is proposed exhibiting relativistic invariance and based on a physical model for vacuum space consisting of the superposition of oppositely charged continuous fluids. Models for the photon, electron, neutrino, proton, etc., consist of separate unique variations in the relative densities of the fluids and their flow patterns. This GUT is also based on the use of transfinite axiomatic number forms and on a concept of metrical relativity which hopefully reconciles the many logical dichotomies in and between Special Relativity and Quantum Mechanics. These ideas result in a number of experimental proposals and predicted results which appear to be underivable from present paradigms, first among which is a physical model for the hidden variable of Quantum Mechanics. It is on these features that attention should rest. (Auth.)

  17. A unified grand tour of theoretical physics

    CERN Document Server

    Lawrie, Ian D

    2013-01-01

    A Unified Grand Tour of Theoretical Physics invites its readers to a guided exploration of the theoretical ideas that shape our contemporary understanding of the physical world at the fundamental level. Its central themes, comprising space-time geometry and the general relativistic account of gravity, quantum field theory and the gauge theories of fundamental forces, and statistical mechanics and the theory of phase transitions, are developed in explicit mathematical detail, with an emphasis on conceptual understanding. Straightforward treatments of the standard models of particle physics and cosmology are supplemented with introductory accounts of more speculative theories, including supersymmetry and string theory. This third edition of the Tour includes a new chapter on quantum gravity, focusing on the approach known as Loop Quantum Gravity, while new sections provide extended discussions of topics that have become prominent in recent years, such as the Higgs boson, massive neutrinos, cosmological perturba...

  18. Gauge-Higgs EW and grand unification

    Science.gov (United States)

    Hosotani, Yutaka

    2016-07-01

    Four-dimensional Higgs field is identified with the extra-dimensional component of gauge potentials in the gauge-Higgs unification scenario. SO(5) × U(1) gauge-Higgs EW unification in the Randall-Sundrum warped space is successful at low energies. The Higgs field appears as an Aharonov-Bohm phase 𝜃H in the fifth dimension. Its mass is generated at the quantum level and is finite. The model yields almost the same phenomenology as the standard model for 𝜃H bosons around 6-10 TeV with very broad widths. The scenario is generalized to SO(11) gauge-Higgs grand unification. Fermions are introduced in the spinor and vector representations of SO(11). Proton decay is naturally forbidden.

  19. Grande Bretagne : Design Guides et Design Codes

    OpenAIRE

    Sadoux, Stéphane

    2010-01-01

    Fortement médiatisée dès le début des années 1990, la crise du logement à laquelle est confronté le New Labour lorsqu'il accède au pouvoir en 1997 propulse une nouvelle fois l'agenda urbain sur le devant de la scène politique britannique. La construction de plus de 4 millions de logements est alors jugée nécessaire pour répondre à la demande latente, et les grandes villes continuent de se vider au profit des suburbs. C'est dans ce climat que Tony Blair nomme l'architecte Richard Rogers à la t...

  20. Grand Banks wins Terra Nova sweeps

    International Nuclear Information System (INIS)

    The Grand Bank Alliance of Companies, which includes Brown and Root and Agra Industries, Haliburton Energy Services, Doris Engineering, FMC Corporation and PCL Constructors, have been awarded the primary fabrication contract by Petro-Canada to build a floating production and storage vessel for the Terra Nova oil project. The total pre-production costs are estimated at $1.6 billion; the first oil is scheduled for 1999. The contract involves construction of a double-hulled floating production, storage and offloading vessel, designed to process up to 150,000 barrels of crude per day, and storing up to one million barrels. In addition to Terra Nova, Brown and Root and Agra also have project management contracts building infrastructure for Sable Island natural gas

  1. Introduction : Gouvernance et grande vitesse

    OpenAIRE

    Belot, Robert

    2015-01-01

    On peut dire que la grande vitesse ferroviaire a été une « révolution » dans la mesure où elle a permis d’appréhender le ferroviaire autrement que comme un simple moyen de transport et d’accroissement de la mobilité. Elle a été regardée et appropriée par les politiques comme une aubaine de transformation et de dynamisation des territoires, comme une promesse de dépassement des frontières et d’accélération du processus d’européanisation, comme une assurance d’égalité sociale et territoriale ma...

  2. Pitié pour les grandes villes !

    Directory of Open Access Journals (Sweden)

    Jérôme Monnet

    1997-02-01

    Full Text Available Roger Caillois disait, en 1938, qu´il existe "une représentation de la grande ville, assez puissante sur les imaginations pour que jamais en pratique ne soit posée la question de son exactitude, créée de toute pièce par le livre, assez répandue néanmoins pour faire partie de l´atmosphère mentale collective et posséder par suite une certaine force de contrainte"(Le mythe et l´homme, p.156 [c´est lui qui souligne]. En 1996, la presse française a consacré dossiers et articles à "Habitat II...

  3. Introduction to Grand Unified Theories. 12

    International Nuclear Information System (INIS)

    This chapter presents an introduction into Grand Unified Theories. After a discussion of the general features to be expected in any such theory, and of the motivations for them, a detailed presentation of SU(5) theory is given. The group structures, particle multiplets, gauge and Higgs bosons are explained. The two stages of spontaneous symmetry breaking via the Higgs model, are calculated individually and in combination. Fermion mass matrices and relations between quark and lepton masses are derived. predictions of SU(5) theory, calculated using renormalization group methods, are derived. The chapter ends with discussions that bring together particle physics and cosmology, including the baryon asymmetry problem, phase transitions in the very early universe, and singularities like domain walls, vortex lines and monopoles. (author). 9 refs.; 4 figs.; 5 tabs

  4. Local grand unification and string theory

    Energy Technology Data Exchange (ETDEWEB)

    Nilles, Hans Peter [Bonn Univ. (Germany). Bethe Center for Theoretical Physics and Physikalisches Inst.; Ramos-Sanchez, Saul [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Vaudrevange, Patrick K.S. [Muenchen Univ. (Germany). Arnold Sommerfeld Center for Theoretical Physics

    2009-09-15

    The low energy effective action of string theory depends strongly on the process of compactification and the localization of fields in extra dimensions. Explicit string constructions towards the minimal supersymmetric standard model (MSSM) reveal interesting results leading to the concept of local grand unification. Properties of the MSSM indicate that we might live at a special location close to an orbifold fixed point rather than a generic point in Calabi-Yau moduli space. We observe an enhancement of (discrete) symmetries that have various implications for the properties of the MSSM such as proton stability as well as solutions to the flavor problem, the m-problem and the strong CP-problem. (orig.)

  5. Quaternion Octonion Reformulation of Grand Unified Theories

    CERN Document Server

    Pushpa,; Li, Tianjun; Negi, O P S

    2012-01-01

    In this paper, Grand Unified theories are discussed in terms of quaternions and octonions by using the relation between quaternion basis elements with Pauli matrices and Octonions with Gell Mann \\lambda matrices. Connection between the unitary groups of GUTs and the normed division algebra has been established to re-describe the SU(5)gauge group. We have thus described the SU(5)gauge group and its subgroup SU(3)_{C}\\times SU(2)_{L}\\times U(1) by using quaternion and octonion basis elements. As such the connection between U(1) gauge group and complex number, SU(2) gauge group and quaternions and SU(3) and octonions is established. It is concluded that the division algebra approach to the the theory of unification of fundamental interactions as the case of GUTs leads to the consequences towards the new understanding of these theories which incorporate the existence of magnetic monopole and dyon.

  6. Gauge-Higgs EW and Grand Unification

    CERN Document Server

    Hosotani, Yutaka

    2016-01-01

    4D Higgs field is identified with the extra-dimensional component of gauge potentials in the gauge-Higgs unification scenario. $SO(5) \\times U(1)$ gauge-Higgs EW unification in the Randall-Sundrum warped space is successful at low energies. The Higgs field appears as an Aharonov-Bohm phase $\\theta_H$ in the fifth dimension. Its mass is generated at the quantum level and is finite. The model yields almost the same phenomenology as the standard model for $\\theta_H < 0.1$, and predicts $Z'$ bosons around 6 - 10 TeV with very broad widths. The scenario is genelarized to $SO(11)$ gauge-Higgs grand unification. Fermions are introduced in the spinor and vector representations of $SO(11)$. Proton decay is naturally forbidden.

  7. 36 CFR 7.4 - Grand Canyon National Park.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Grand Canyon National Park. 7.4 Section 7.4 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.4 Grand Canyon National Park. (a)...

  8. Gauge coupling unification in gauge-Higgs grand unification

    Science.gov (United States)

    Yamatsu, Naoki

    2016-04-01

    We discuss renormalization group equations for gauge coupling constants in gauge-Higgs grand unification on five-dimensional Randall-Sundrum warped space. We show that all four-dimensional Standard Model gauge coupling constants are asymptotically free and are effectively unified in SO(11) gauge-Higgs grand unified theories on 5D Randall-Sundrum warped space.

  9. Gauge Coupling Unification in Gauge-Higgs Grand Unification

    CERN Document Server

    Yamatsu, Naoki

    2015-01-01

    We discuss renormalization group equations for gauge coupling constants in gauge-Higgs grand unification on five-dimensional Randall-Sundrum warped space. We show that all the four-dimensional Standard Model gauge coupling constants are asymptotically free and are effectively unified in $SO(11)$ gauge-Higgs grand unified theories on 5D Randall-Sundrum warped space.

  10. Grand canonical potential of a magnetized neutron gas

    CERN Document Server

    Diener, Jacobus P W

    2015-01-01

    We compute the effective action for stationary and spatially constant magnetic fields, when coupled anomalously to charge neutral fermions, by integrating out the fermions. From this the grand canonical partition function and potential of the fermions and fields are computed. This also takes care of magnetic field dependent vacuum corrections to the grand canonical potential. Possible applications to neutron stars are indicated.

  11. L’Apocalypse selon Jean Giono : du "Grand Troupeau" au "Grand Théâtre"

    OpenAIRE

    Bonnet, Dominique

    2013-01-01

    Dans cet article nous chercherons à comprendre quel était pour Jean Giono le véritable sens de l’Apocalypse depuis l’analyse d’un de ses premiers romans Le Grand Troupeau jusqu’à l’un de ses textes les plus récents et pourtant moins connu, Le Grand Théâtre; texte qui, par ailleurs, répond à une commande de Joseph Foret en vue de la publication d’une édition de prestige de l’Apocalypse de Saint Jean. Nous verrons comment Jean Giono nous présente sa vision particulière de l’Apoca...

  12. Parallel Grand Canonical Monte Carlo (ParaGrandMC) Simulation Code

    Science.gov (United States)

    Yamakov, Vesselin I.

    2016-01-01

    This report provides an overview of the Parallel Grand Canonical Monte Carlo (ParaGrandMC) simulation code. This is a highly scalable parallel FORTRAN code for simulating the thermodynamic evolution of metal alloy systems at the atomic level, and predicting the thermodynamic state, phase diagram, chemical composition and mechanical properties. The code is designed to simulate multi-component alloy systems, predict solid-state phase transformations such as austenite-martensite transformations, precipitate formation, recrystallization, capillary effects at interfaces, surface absorption, etc., which can aid the design of novel metallic alloys. While the software is mainly tailored for modeling metal alloys, it can also be used for other types of solid-state systems, and to some degree for liquid or gaseous systems, including multiphase systems forming solid-liquid-gas interfaces.

  13. Elastoplasticidad anisotropa de metales en grandes deformaciones

    Science.gov (United States)

    Caminero Torija, Miguel Angel

    El objetivo de este trabajo es el desarrollo de modelos y algoritmos numericos que simulen el comportamiento del material bajo estas condiciones en el contexto de programas de elementos finitos, dando como resultado predicciones mas precisas de los procesos de conformado y deformacion plastica en general. Para lograr este objetivo se han desarrollado diversas tareas destinadas a mejorar las predicciones en tres aspectos fundamentales. El primer aspecto consiste en la mejora de la descripcion del endurecimiento cinematico anisotropo en pequenas deformaciones, lo cual se ha realizado a traves de modelos y algoritmos implicitos de superficies multiples. Ha sido estudiada la consistencia de este tipo de modelos tanto si estan basados en una regla implicita similar a la de Mroz o en la regla de Prager. Ademas se han simulado los ensayos de Lamba y Sidebottom, obteniendo, en contra de la creencia general, muy buenas predicciones con la regla de Prager. Dichos modelos podrian ser extendidos de forma relativamente facil para considerar grandes deformaciones a traves de procedimientos en deformaciones logaritmicas, similares a los desarrollados en esta tesis y detallados a continuacion. El segundo aspecto consiste en la descripcion de la anisotropia elastoplastica inicial. Esto se ha conseguido mediante el desarrollo de modelos y algoritmos para plasticidad anisotropa en grandes deformaciones, bien ignorando la posible anisotropia elastica, bien considerandola simultaneamente con la anisotropia plastica. Para ello ha sido necesario desarrollar primero un nuevo algoritmo de elastoplasticidad anisotropa en pequenas deformaciones consistentemente linealizado y sin despreciar ningun termino, de tal forma que se conserve la convergencia cuadratica de los metodos de Newton. Este algoritmo en pequenas deformaciones ha servido para realizar la correccion plastica de dos algoritmos en grandes deformaciones. El primero de estos algoritmos es una variacion del clasico algoritmo de

  14. Sleep bruxism: challenges and restorative solutions

    OpenAIRE

    Mengatto CM; Coelho-de-Souza FH; Souza Junior OB

    2016-01-01

    Cristiane Machado Mengatto, Fábio Herrmann Coelho-de-Souza, Oswaldo Baptista de Souza Junior Department of Conservative Dentistry, School of Dentistry, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil Abstract: Bruxism is a parafunctional activity related to clenching or grinding the teeth and tooth wear can be a consequence of sleep bruxism (SB). Management of severe tooth wear due to SB is a challenging situation because of the common reduced amount of remai...

  15. Sleep bruxism: challenges and restorative solutions

    OpenAIRE

    Mengatto CM; Coelho-de-Souza FH; Souza Junior OB

    2016-01-01

    Cristiane Machado Mengatto, Fábio Herrmann Coelho-de-Souza, Oswaldo Baptista de Souza Junior Department of Conservative Dentistry, School of Dentistry, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil Abstract: Bruxism is a parafunctional activity related to clenching or grinding the teeth and tooth wear can be a consequence of sleep bruxism (SB). Management of severe tooth wear due to SB is a challenging situation because of the common reduced amount of remaining...

  16. Featherweight Challenge

    Science.gov (United States)

    Love, Tyler S.; Ryan, Larry

    2012-01-01

    As science, technology education, and engineering programs suffer budget cuts, educators continue to seek cost-effective activities that engage students and reinforce standards. The featherweight challenge is a hands-on activity that challenges students to continually refine their design while not breaking the budget. This activity uses one of the…

  17. Report: pipeline transport of solid waste in the Grand Holy Mosque in Makkah.

    Science.gov (United States)

    Al-Ghamdi, Abdullah Saeed; Abu-Rizaiza, Asad Seraj

    2003-10-01

    The Grand Holy Mosque, located in the Holy City of Makkah in Saudi Arabia, attracts millions of Muslim visitors from all over the world, especially during the pilgrimage season. The daily amount of refuse generated in the Grand Holy Mosque and surrounding plazas reached a maximum value of 192.8 tons/day in 1998. Collection and transport of the solid waste generated during the peak times present a challenge to the Makkan authorities. The congested streets and high population density in the Holy Mosque and its surrounding plazas make the traditional methods of collecting and transporting solid waste impractical. This paper presents an alternative system for the collection and transport of solid waste generated in and around the Grand Holy Mosque in Makkah. The proposed system is based on a pneumatic transport technique, by which the waste is collected and transported in underground pipelines. A conceptual layout of the proposed system in the Mosque area is presented, and the merits of the suggested system are discussed. PMID:14661895

  18. The People-First Service of Grand Hotel Beijing

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Grand Hotel Beijing is located north of Chang’an Avenue and east of the landmark Forbidden City in Beijing.This five-star luxury hotel has received numerous government delegations and state leaders from around the world since it opened in 1990.Wang Fuhe has been General Manager of Grand Hotel Beijing for more than 10 years.Through the effortsofWangandhisteam,thehotelflagshipsteers steady and fast,taking a leading position among the countless luxury hotels in Beijing.Wang attributes the success of Grand Hotel Beijing to its distinctive

  19. Grandes sistemas fluviais tropicais: uma visão geral

    OpenAIRE

    Rajiv Sinha; Edgardo Manuel Latrubesse; José Cândido Stevaux

    2010-01-01

    Muitos dos grandes rios e dos leques aluviais existentes estão situados em áreas tropicais e constituem os maiores sistemas de estoque e transferência de sedimentos e nutrientes para o oceano. O presente trabalho visa a apresentação e análise geral dos grandes sistemas fluviais e leques aluviais (área da bacia entre 104 e 6 x 106 km ) de regiões tropicais com precipitação acima de 700 mm anuais. Os grandes sistemas fluviais ...

  20. Development of a methylation marker set for forensic age estimation using analysis of public methylation data and the Agena Bioscience EpiTYPER system.

    Science.gov (United States)

    Freire-Aradas, A; Phillips, C; Mosquera-Miguel, A; Girón-Santamaría, L; Gómez-Tato, A; Casares de Cal, M; Álvarez-Dios, J; Ansede-Bermejo, J; Torres-Español, M; Schneider, P M; Pośpiech, E; Branicki, W; Carracedo, Á; Lareu, M V

    2016-09-01

    Individual age estimation has the potential to provide key information that could enhance and extend DNA intelligence tools. Following predictive tests for externally visible characteristics developed in recent years, prediction of age could guide police investigations and improve the assessment of age-related phenotype expression patterns such as hair colour changes and early onset of male pattern baldness. DNA methylation at CpG positions has emerged as the most promising DNA tests to ascertain the individual age of the donor of a biological contact trace. Although different methodologies are available to detect DNA methylation, EpiTYPER technology (Agena Bioscience, formerly Sequenom) provides useful characteristics that can be applied as a discovery tool in localized regions of the genome. In our study, a total of twenty-two candidate genomic regions, selected from the assessment of publically available data from the Illumina HumanMethylation 450 BeadChip, had a total of 177 CpG sites with informative methylation patterns that were subsequently investigated in detail. From the methylation analyses made, a novel age prediction model based on a multivariate quantile regression analysis was built using the seven highest age-correlated loci of ELOVL2, ASPA, PDE4C, FHL2, CCDC102B, C1orf132 and chr16:85395429. The detected methylation levels in these loci provide a median absolute age prediction error of ±3.07years and a percentage of prediction error relative to the age of 6.3%. We report the predictive performance of the developed model using cross validation of a carefully age-graded training set of 725 European individuals and a test set of 52 monozygotic twin pairs. The multivariate quantile regression age predictor, using the CpG sites selected in this study, has been placed in the open-access Snipper forensic classification website. PMID:27337627

  1. The grand descent has begun for CMS

    CERN Multimedia

    2006-01-01

    Until recently, the CMS experimental cavern looked relatively empty; its detector was assembled entirely at ground level, to be lowered underground in 15 sections. On 2 November, the first hadronic forward calorimeter led the way with a grand descent. The first section of the CMS detector (centre of photo) arriving from the vertical shaft, viewed from the cavern floor. There is something unusual about the construction of the CMS detector. Instead of being built in the experimental cavern, like all the other detectors in the LHC experiments, it was constructed at ground level. This was to allow for easy access during the assembly of the detector and to minimise the size of the excavated cavern. The slightly nerve-wracking task of lowering it safely into the cavern in separate sections came after the complete detector was successfully tested with a magnetic field at ground level. In the early morning of 2 November, the first section of the CMS detector began its eagerly awaited descent into the underground ca...

  2. Convective Dynamo Simulation with a Grand Minimum

    Science.gov (United States)

    Augustson, Kyle C.; Brun, A. S.; Miesch, Mark; Toomre, Juri

    2015-01-01

    The global-scale dynamo action achieved in a simulation of a Sun-like star rotating at thrice the solar rate is assessed. The 3-D MHD Anelastic Spherical Harmonic (ASH) code, augmented with a viscosity minimization scheme, is employed to capture convection and dynamo processes in this G-type star. The simulation is carried out in a spherical shell that encompasses 3.8 density scale heights of the solar convection zone. It is found that dynamo action with a high degree of time variation occurs, with many periodic polarity reversals occurring roughly every 6.2 years. The magnetic energy also rises and falls with a regular period. The magnetic energy cycles arise from a Lorentz-force feedback on the differential rotation, whereas the processes leading to polarity reversals are more complex, appearing to arise from the interaction of convection with the mean toroidal fields. Moreover, an equatorial migration of toroidal field is found, which is linked to the changing differential rotation, and potentially to a nonlinear dynamo wave. This simulation also enters a grand minimum lasting roughly 20 years, after which the dynamo recovers its regular polarity cycles.

  3. A unified grand tour of theoretical physics

    CERN Document Server

    Griffiths, J

    2002-01-01

    Anyone offering a grand tour is faced with several options. Should they concentrate on what may be considered to be essential features, or should they attempt to present a brief glimpse of almost everything? The present offering is a compromise between these two extremes. The area considered - theoretical physics - is now such a vast subject that some kind of compromise is essential. Indeed, the field is now so wide that few could even attempt to review it in a single-authored work. My task here is to assess how well this book has succeeded in its main aim of providing a unified (though introductory) tour of this subject. Constrained within a single volume, this is clearly not an updated Landau-Lifschitz. It cannot be expected to take any particular topic to the level of recent research. Nevertheless, it does seem to cover the broad range of essential topics which now constitute the subject. It starts (most appropriately in my opinion) with geometry. It then covers classical physics, general relativity and qu...

  4. Integrated telemedicine workstation for intercontinental grand rounds

    Science.gov (United States)

    Willis, Charles E.; Leckie, Robert G.; Brink, Linda; Goeringer, Fred

    1995-04-01

    The Telemedicine Spacebridge to Moscow was a series of intercontinental sessions sponsored jointly by NASA and the Moscow Academy of Medicine. To improve the quality of medical images presented, the MDIS Project developed a workstation for acquisition, storage, and interactive display of radiology and pathology images. The workstation was based on a Macintosh IIfx platform with a laser digitizer for radiographs and video capture capability for microscope images. Images were transmitted via the Russian Lyoutch Satellite which had only a single video channel available and no high speed data channels. Two workstations were configured -- one for use at the Uniformed Services University of Health Sciences in Bethesda, MD. and the other for use at the Hospital of the Interior in Moscow, Russia. The two workstations were used may times during 16 sessions. As clinicians used the systems, we modified the original configuration to improve interactive use. This project demonstrated that numerous acquisition and output devices could be brought together in a single interactive workstation. The video images were satisfactory for remote consultation in a grand rounds format.

  5. Local grand unification in the heterotic landscape

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, Jonas

    2009-07-15

    We consider the possibility that the unification of the electroweak interactions and the strong force arises from string theory, at energies significantly lower than the string scale. As a tool, an effective grand unified field theory in six dimensions is derived from an anisotropic orbifold compactification of the heterotic string. It is explicitly shown that all anomalies cancel in the model, though anomalous Abelian gauge symmetries are present locally at the boundary singularities. In the supersymmetric vacuum additional interactions arise from higher-dimensional operators. We develop methods that relate the couplings of the effective theory to the location of the vacuum, and find that unbroken discrete symmetries play an important role for the phenomenology of orbifold models. An efficient algorithm for the calculation of the superpotential to arbitrary order is developed, based on symmetry arguments. We furthermore present a correspondence between bulk fields of the orbifold model in six dimensions, and the moduli fields that arise from compactifying four internal dimensions on a manifold with non-trivial gauge background. (orig.)

  6. Toward Realistic Gauge-Higgs Grand Unification

    CERN Document Server

    Furui, Atsushi; Yamatsu, Naoki

    2016-01-01

    The $SO(11)$ gauge-Higgs grand unification in the Randall-Sundrum warped space is presented. The 4D Higgs field is identified as the zero mode of the fifth dimensional component of the gauge potentials, or as the fluctuation mode of the Aharonov-Bohm phase $\\theta_H$ along the fifth dimension. Fermions are introduced in the bulk in the spinor and vector representations of $SO(11)$. $SO(11)$ is broken to $SO(4) \\times SO(6)$ by the orbifold boundary conditions, which is broken to $SU(2)_L \\times U(1)_Y \\times SU(3)_C$ by a brane scalar. Evaluating the effective potential $V_{\\rm eff} (\\theta_H)$, we show that the electroweak symmetry is dynamically broken to $U(1)_{\\rm EM}$. The quark-lepton masses are generated by the Hosotani mechanism and brane interactions, with which the observed mass spectrum is reproduced. The proton decay is forbidden thanks to the new fermion number conservation. It is pointed out that there appear light exotic fermions. The Higgs boson mass is determined with the quark-lepton masses ...

  7. A Proportional Wire Chamber Array: GRAND's Status

    CERN Document Server

    Poirier, J; Puerto, M L; Strahler, E A; Vermedahl, J

    2003-01-01

    Project GRAND is a 100m x 100m air shower array of position sensitive proportional wire chambers (PWCs) located at 41.7 degrees North and 86.2 degrees West at an elevation of 220m above sea level. Its convenient location adjacent to the campus of the University of Notre Dame makes it a good training ground for students. There are 64 stations each with eight 1.29 m^2 PWCs. The geometry of the stations allows for the angles of charged secondaries to be determined to within 0.26 degrees in each of two orthogonal planes; muons are differentiated from electrons and hadrons by means of a steel plate. Two triggers are run simultaneously: a multiple hit coincidence trigger, rich in extensive air showers, and a single track trigger, rich in secondary muon tracks. The former trigger is sensitive to primary energies greater than ~100 TeV, the latter to energies greater than ~10 GeV.

  8. Enterotoxemia em caprinos no Rio Grande do Sul Caprine enterotoxaemia in Rio Grande do Sul, Brazil

    OpenAIRE

    Colodel, Edson M; David Driemeier; Milene Schmitz; Marlise Germer; Ricardo A. P. Nascimento; Ronnie A. Assis; Francisco C.F. Lobato; Uzal, Francisco A.

    2003-01-01

    São descritos surtos de enterotoxemia em caprinos em cinco propriedades no Estado do Rio Grande do Sul. Os animais afetados eram, normalmente, encontrados mortos ou apresentavam evolução aguda de 2 a 3 horas com acentuada depressão, cólicas abdominais e diarréia profusa com fibrina. Em duas propriedades relataram-se casos com a evolução de até 12 horas. Em treze animais necropsiados observaram-se aumento de líquidos nas cavidades abdominal, torácica e pericárdica, congestão e hiperemia da ser...

  9. Grand Bay National Wildlife Refuge: Comprehensive Conservation Plan

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This Comprehensive Conservation Plan (CCP) was written to guide management on Grand Bay NWR for the next 15 years. This plan outlines the Refuge vision and purpose...

  10. The KASCADE-Grande Experiment and the LOPES Project

    CERN Document Server

    Badea, A F; Apel, W D; Bekk, K; Bercuci, A; Bertaina, M; Blümer, H; Bozdog, H; Brancus, I M; Bruggemann, M; Bucholz, P; Chiavassa, A; Daumiller, K; di Pierro, F; Doll, P; Engel, R; Engler, J; Falcke, H; Fessler, F; Ghia, P L; Gils, H J; Glasstetter, R; Haungs, A; Heck, D; Hörandel, J R; Horneffer, A; Huege, T; Kampert, K H; Kant, G W; Klages, H O; Kolotaev, Yu; Maier, G; Mathes, H J; Mayer, H J; Milke, J; Morello, C; Müller, M; Navarra, G; Obenland, R; Oehlschläger, J; Ostapchenko, S; Petcu, M; Plewnia, S; Rebel, H; Risse, A; Roth, M; Schieler, H; Scholz, J; Stumpert, M; Thouw, T; Toma, G; Trinchiero, G C; Ulrich, H; Valchierotti, S; Van Buren, J; De Vos, C M; Walkowiak, W; Weindl, A; Wochele, J; Zabierowski, J; Zagromski, S; Zimmermann, D

    2004-01-01

    KASCADE-Grande is the extension of the multi-detector setup KASCADE to cover a primary cosmic ray energy range from 100 TeV to 1 EeV. The enlarged EAS experiment provides comprehensive observations of cosmic rays in the energy region around the knee. Grande is an array of 700 x 700 sqm equipped with 37 plastic scintillator stations sensitive to measure energy deposits and arrival times of air shower particles. LOPES is a small radio antenna array to operate in conjunction with KASCADE-Grande in order to calibrate the radio emission from cosmic ray air showers. Status and capabilities of the KASCADE-Grande experiment and the LOPES project are presented.

  11. Riesz's and Bessel's Operators in Bilateral Grand Lebesgue Spaces

    CERN Document Server

    Ostrovsky, E; Sirota, L

    2009-01-01

    In this paper we obtain the non - asymptotic estimations for Riesz's and Bessel's potential integral operators in the so - called Bilateral Grand Lebesgue Spaces. We also give examples to show the sharpness of these inequalities.

  12. Grand Cote National Wildlife Refuge: Comprehensive Conservation Plan

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This Comprehensive Conservation Plan CCP was written to guide management on Grand Cote NWR for the next 15 years. This plan outlines the Refuge vision and purpose...

  13. Species status assessment report for the Rio Grande cutthroat trout

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The Rio Grande cutthroat trout (Oncorhynchus clarkii virginalis) lives in high elevation, coldwater streams in New Mexico and southern Colorado. It is a subspecies...

  14. Casa Grande Ruins National Monument Vegetation Mapping Project - Plot Locations

    Data.gov (United States)

    National Park Service, Department of the Interior — This layer contains spatial information for 25 plots sampled during vegetation mapping and classification efforts at Casa Grande Ruins NM, AZ. Data was collected by...

  15. Grand Bay National Wildlilfe Refuge [Land Status Map

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This map was produced by the Division of Realty to depict landownership at Grand Bay National Wildlife Refuge. It was generated from rectified aerial photography,...

  16. Canonical versus grand canonical treatment of the conservation laws

    International Nuclear Information System (INIS)

    The differences between the canonical and the grand canoncial treatment of the conservation laws in the relativistic statistical thermodynamics are discussed. The possible implications on the thermodynamics description of hadronic matter created in particle or ion collisions are considered

  17. Albuquerque/Middle Rio Grande Urban Waters Viewer

    Data.gov (United States)

    U.S. Environmental Protection Agency — These data have been compiled in support of the Middle Rio Grande/Albuquerque Urban Waters Partnership for the region including Albuquerque, New Mexico.The Middle...

  18. Grand Cote National Wildlife Refuges Habitat Management Plan

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The Grand Cote NWR Habitat Management Plan provides a longterm vision and specific guidance on managing habitats for the resources of concern at the Refuge, to...

  19. Female homicide in Rio Grande do Sul, Brazil

    OpenAIRE

    Gabriela Tomedi Leites; Stela Nazareth Meneghel; Vania Noemi Hirakata

    2014-01-01

    This study aimed to assess the female homicide rate due to aggression in Rio Grande do Sul, Brazil, using this as a "proxy" of femicide. This was an ecological study which correlated the female homicide rate due to aggression in Rio Grande do Sul, according to the 35 microregions defined by the Brazilian Institute of Geography and Statistics (IBGE), with socioeconomic and demographic variables access and health indicators. Pearson's correlation test was performed with the selected variables. ...

  20. Grand Projection State: Bridge between Thermodynamic Variables and Spatial Constraint

    OpenAIRE

    Yuge, Koretaka

    2016-01-01

    In classical systems, we reexamine the relationship between thermodynamic variables (especially, focusing on grand potential and free energy) and spatial constraint on the constituents. We find that for R-component system, free energy in equilibrium disordered states can be well-characterized by 2(R-1) special microscopic states, which we call "grand projection states" (GP states). While the free energy depends on interactions, chemical potential and temperature, the GP states depend only on ...

  1. The canonical and grand canonical models for nuclear multifragmentation

    Indian Academy of Sciences (India)

    G Chaudhuri; S Das Gupta

    2010-08-01

    Many observables seen in intermediate energy heavy-ion collisions can be explained on the basis of statistical equilibrium. Calculations based on statistical equilibrium can be implemented in microcanonical ensemble, canonical ensemble or grand canonical ensemble. This paper deals with calculations with canonical and grand canonical ensembles. A recursive relation developed recently allows calculations with arbitrary precision for many nuclear problems. Calculations are done to study the nature of phase transition in nuclear matter.

  2. Triality and the grand canonical ensemble in QCD

    International Nuclear Information System (INIS)

    QCD in the usual finite temperature formulation is using the grand canonical ensemble with chemical potential zero. We demonstrate that this description may give wrong predictions. QCD in the canonical formulation does not explicitly break Z(3) symmetry. It behaves in this sense like pure gluonic QCD. There are no metastable states in the canonical ensemble description as predicted in the grand canonical ensemble formalism. ((orig.))

  3. Tres grandes plataformas marinas Mar del Norte

    Directory of Open Access Journals (Sweden)

    Soulas, R.

    1978-03-01

    Full Text Available This article analyzes the different building stages of three large sea platforms. After studying the structure's main characteristics, preparing scale models and calculating ail the elements, platform construction was carried out in three stages: — Dry-dock construction of the hull base. — Installation in the water and finishing the structure. — Immersion and bridge installation. Finally, the necessary operations to move the platform to its definite location were carried out. The structures are formed by a parallelepiped hull of reinforced concrete, divided into compartments by means of vertical orthogonals panels on top of which 2 or 4 piles are placed to support the bridge.

    En este artículo se analizan las diversas etapas en la realización de tres grandes plataformas marinas. Después de un estudio de las características principales de la estructura, ensayos en modelo reducido y cálculo de todos los elementos, se procede a la construcción de las plataformas en tres fases: — Construcción en seco de la base del casco. — Colocación en el agua y acabado de la estructura. — Inmersión y colocación del puente. Por último, se realizan las operaciones necesarias para llevar la plataforma a su ubicación definitiva. Las estructuras están formadas por un casco paralelepipédico de hormigón armado, dividido en compartimientos mediante tabiques verticales ortogonales y sobre el que se han colocado 2 ó 4 pilas que soportan el puente.

  4. A COMPARATIVE STUDY TO ASSES THE OUTCOME OF GRAND MULTIPARA WITH THAT OF GREAT GRAND MULTIPARA

    Directory of Open Access Journals (Sweden)

    Nayana

    2015-01-01

    Full Text Available NEED FOR THE STUDY: In a developing country like India , where poverty , illiteracy , ignorance and lack of knowledge of family planning facilities available have greatly increased the incidence of grandmultipara 2. Grandmultipara has been associated with increased maternal morbidity and mortality rat es as well as poor outcome. The investigator is interested in finding out the outcome in grand multipara women and great grand multipara 1 women during the antenatal , internatal and postnatal period , and also to analyze demographic characteristics such as socioeconomic status and religion of the sample. STATEMENT OF THE PROBLEM: A comparative study to assess the outcome of grandmultipara (1 with that of grandmultipara women. OBJECTIVE OF THE STUDY: 1. To findout the outcome of grandmultipara women during th e antenatal , internatal and postnatal period. 2. To find the outcome of great grandmultipara women during the antenatal , internatal (2 and postnatal period. 3. To compare the outcomes of grandmultipara with that of non - grandmultipara women during the anten atal , internatal and postnatal (3 period. ( 4 To analyze the demographic characteristics 6 of the sample i.e. income and religion.

  5. Logistical challenges

    Directory of Open Access Journals (Sweden)

    Steve Matthews

    2005-07-01

    Full Text Available The impact of the Asian tsunami was unprecedented and the logistical challenges of meeting the needs of those affected were enormous. Had the tsunami happened even five years ago, World Vision would not have been able to respond nearly as effectively as it did.

  6. Mobility Challenges

    DEFF Research Database (Denmark)

    Jensen, Ole B.; Lassen, Claus

    2011-01-01

    This article takes point of departure in the challenges to understand the importance of contemporary mobility. The approach advocated is a cross-disciplinary one drawing on sociology, geography, urban planning and design, and cultural studies. As such the perspective is to be seen as a part of th...

  7. Ethical Challenges

    Science.gov (United States)

    Morris, Michael

    2004-01-01

    All evaluators face the challenge of striving to adhere to the highest possible standards of ethical conduct. Translating the AEA's Guiding Principles and the Joint Committee's Program Evaluation Standards into everyday practice, however, can be a complex, uncertain, and frustrating endeavor. Moreover, acting in an ethical fashion can require…

  8. Editorial Challenges

    OpenAIRE

    Budin, Wendy C.

    2008-01-01

    In this column, the editor of The Journal of Perinatal Education (JPE) discusses some of the challenges involved in becoming the new editor of JPE. The editor also describes the contents of this issue, which offer a broad range of resources, research, and inspiration for childbirth educators in their efforts to promote normal birth.

  9. Archiving challenges

    OpenAIRE

    Ringersma, J.

    2010-01-01

    Teaching slides on: What is a digital archive? Parties involved in digital archiving Archiving challenges organization of data coherence and persistency access and safety Language archiving software Different users, different needs For: Saami Language Documentation and Revitalization. Winter school, Bodø, Norway

  10. Le personnage du scientifique : « Challenger, George Edward1 »

    OpenAIRE

    Machinal, Hélène

    2016-01-01

    Comme Sherlock Holmes, le professeur Challenger est sans conteste une très grande création de Doyle. De même que l’auteur a su ménager dans le personnage de Holmes des zones d’ombres qui lui confèrent sa profondeur, le personnage de Challenger comporte une dimension grotesque qui pourrait paraître étrange chez un personnage incarnant par ailleurs l’homme de science par excellence. Challenger est présenté comme le digne successeur des plus grands noms de l’époque. Son autorité scientifique éta...

  11. Enterotoxemia em caprinos no Rio Grande do Sul Caprine enterotoxaemia in Rio Grande do Sul, Brazil

    Directory of Open Access Journals (Sweden)

    Edson M. Colodel

    2003-12-01

    Full Text Available São descritos surtos de enterotoxemia em caprinos em cinco propriedades no Estado do Rio Grande do Sul. Os animais afetados eram, normalmente, encontrados mortos ou apresentavam evolução aguda de 2 a 3 horas com acentuada depressão, cólicas abdominais e diarréia profusa com fibrina. Em duas propriedades relataram-se casos com a evolução de até 12 horas. Em treze animais necropsiados observaram-se aumento de líquidos nas cavidades abdominal, torácica e pericárdica, congestão e hiperemia da serosa e mucosa do intestino, conteúdo do cólon líquido com fibrina além de hemorragias de serosa e fibrina. Em um animal constatou-se microangiopatia cerebral caracterizada por acúmulo de material homogêneo e eosinofílico no espaço perivascular. No conteúdo intestinal, colônias com bastonetes morfológica e bioquimicamente sugestivos de Clostridium perfringens foram caracterizadas no estudo bacteriológico. A soroneutralização em camundongos com conteúdo intestinal dos animais afetados, revelou a presença da toxina épsilon. Estes achados evidenciam a enterotoxemia como doença de importância para criação de caprinos no Rio Grande do Sul.Five outbreaks of caprine enterotoxaemia in Rio Grande do Sul, Brazil, were studied. The animals were found dead or had a clinical course that usually lasted 2-3 hours. From two farms a clinical manifestation period of 12 hours was reported. Clinical signs were characterized by depression, marked abdominal discomfort, profuse watery diarrhea with fibrin clots, and death. Thirteen necropsies were performed and hydropericardium, hydrothorax and hydroperitoneum were commonly found. The mucosa and serosa of the colon were congested, and its contents was watery with multiple fibrin clots. Serosal hemorrhages and fibrin clots in the gallbladder were also seen. Fibrinous colitis and thyphilitis were the most frequent histological changes. Cerebral microangiopathy was observed in one case, which was

  12. Cassini's Grand Finale: The Final Orbits

    Science.gov (United States)

    Spilker, Linda; Edgington, Scott

    2016-04-01

    The Cassini-Huygens mission, a joint collaboration between NASA, ESA and the Italian Space Agency, is approaching its last year of operations after nearly 12 years in orbit around Saturn. Cassini will send back its final bits of unique data on September 15th, 2017 as it plunges into Saturn's atmosphere, vaporizing and satisfying planetary protection requirements. Before that time Cassini will continue its legacy of exploration and discovery with 12 close flybys of Titan in 2016 and 2017 that will return new science data as well as sculpt the inclinations and periods of the final orbits. Even though all of our close icy satellite flybys, including those of Enceladus, are now completed, numerous Voyager-class flybys (solstice approaches. In November 2016 Cassini will transition to a series of orbits with peripases just outside Saturn's F ring. These 20 orbits will include close flybys of some tiny ring moons and excellent views of the F ring and outer A ring. The 126th and final close flyby of Titan will propel Cassini across Saturn's main rings and into its final orbits. Cassini's Grand Finale, starting in April 2017, is comprised of 22 orbits at an inclination of 63 degrees. Cassini will repeatedly dive between the innermost rings and the upper atmosphere of the planet providing insights into fundamental questions unattainable during the rest of the mission. Cassini will be the first spacecraft to explore this region. These close orbits provide the highest resolution observations of both the rings and Saturn, and direct in situ sampling of the ring particles, composition, plasma, Saturn's exosphere and the innermost radiation belts. Saturn's gravitational field will be measured to unprecedented accuracy, providing information on the interior structure of the planet, winds in the outer layers of Saturn's atmosphere, and the mass distribution in the rings. Probing the magnetic field will give insight into the nature of the magnetic dynamo, telling us: why the

  13. CHALLENGES IN BRONCHIAL CHALLENGE TESTING

    NARCIS (Netherlands)

    Lexmond, A. J.; Hagedoorn, P.; Frijlink, H. W.; de Boer, A. H.

    2013-01-01

    Background: In the adenosine 5'-monophosphate (AMP) bronchial challenge test, AMP is usually administered according to dosing protocols developed for histamine/methacholine. It has never been thoroughly investigated whether these protocols are suitable for AMP as well. Methods: The setup of the two-

  14. Chemical Contamination of the Lower Rio Grande near Laredo, TX

    Science.gov (United States)

    Flores, B.; Ren, J.; Krishnamurthy, S.; Belzer, W.

    2006-12-01

    The Rio Grande River stretches over 2000 miles from the southern Rocky Mountains in Colorado to the tip of Texas where the Rio Grande meets the Gulf of Mexico. It is the natural boundary between U.S. and Mexico from El Paso, TX, to Brownsville, TX. The communities along the border heavily rely upon the Rio Grande as a primary source of water for consumption, agricultural uses, supporting wildlife and recreation. For many years the Rio Grande has been polluted with municipal, industrial, agricultural and farming contaminants from both sides of the border. This pollution has led to the extinction or reduction of certain wildlife species as well as affecting the health of the residences along the border. Even though great strides have been made in monitoring the Rio Grande, there has been a lack of intense monitoring data collection for pollutants such as pesticides. Three sampling sites including Manadas Creek, the Rio Grande River at International Bridge I, and USGS monitoring site 08459200 off of Highway 83 were chosen. The water quality parameters focused include temperature, pH, conductivity, dissolve oxygen (DO), salinity, total dissolved solids, nutrients, metals and pesticides. Preliminary results have shown elevated concentration of total phosphorus and ortho-phosphorus in the Manadas Creek site. Organochlorinated pesticides such as heptachlor and 4, 4 DDE were detected at various concentrations at all sites and endrin aldehyde was found at Manadas Creek site. This research has provided more information on the current chemical contamination level of the Rio Grande in the Laredo area.

  15. Sistemas grandes de números o sistemas de números grandes

    OpenAIRE

    Oostra, Arnold

    2008-01-01

    Esta es una reflexión sobre la pregunta: ¿Existen conjuntos de números con carnalidad mayor que la de los reales? Los sistemas numéricos más empleados en la matemática se agrupan en tres clases cuando se los observa desde el punto de vista cardinal: los finitos, los que tienen el cardinal de los naturales y los que tienen el de los reales. ¿Existen sistemas numéricos más grandes? Por supuesto, primero debería precisarse qué puede entenderse por “sistema numérico”, pero aquí no se ahondará en ...

  16. Global challenges

    International Nuclear Information System (INIS)

    A major challenge now facing the world is the supply of energy needed for growth and development in a manner which is not only economically viable but also environmentally acceptable and sustainable in view of the demands of and risks to future generations. The internationally most significant pollutants from energy production through fossil fuels are SO2 and NOx which cause acid rain, and CO2 which is the most significant contributor to the greenhouse effect. Nuclear power, now providing about 17% of the world's electricity and 5% of the primary energy already is making a notable contribution to avoiding these emissions. While the industrialized countries will need more energy and especially electricity in the future, the needs of the developing countries are naturally much larger and present a tremendous challenge to the shaping of the world's future energy supply system. The advanced countries will have to accept special responsibilities, as they can most easily use advanced technologies and they have been and remain the main contributors to the environmental problems we now face. Energy conservation and resort to new renewable energy sources, though highly desirable, appear inadequate alone to meet the challenges. The world can hardly afford to do without an increased use of nuclear power, although it is strongly contested in many countries. The objections raised against the nuclear option focus on safety, waste management and disposal problems and the risk for proliferation of nuclear weapons. These issues are not without their problems. The risk of proliferation exists but will not appreciably diminish with lesser global reliance on nuclear power. The waste issue is more of a political than a technical problem. The use of nuclear power, or any other energy source, will never be at zero risk, but the risks are constantly reduced by new techniques and practices. The IAEA sees it as one of its priority tasks to promote such techniques. (author)

  17. A Unified Grand Tour of Theoretical Physics

    International Nuclear Information System (INIS)

    Anyone offering a grand tour is faced with several options. Should they concentrate on what may be considered to be essential features, or should they attempt to present a brief glimpse of almost everything? The present offering is a compromise between these two extremes. The area considered - theoretical physics - is now such a vast subject that some kind of compromise is essential. Indeed, the field is now so wide that few could even attempt to review it in a single-authored work. My task here is to assess how well this book has succeeded in its main aim of providing a unified (though introductory) tour of this subject. Constrained within a single volume, this is clearly not an updated Landau-Lifschitz. It cannot be expected to take any particular topic to the level of recent research. Nevertheless, it does seem to cover the broad range of essential topics which now constitute the subject. It starts (most appropriately in my opinion) with geometry. It then covers classical physics, general relativity and quantum theory before moving on to relativistic field theories, statistical mechanics and more modern developments. Naturally, the choice of material to be included in a tour of this kind must depend heavily on the prejudices of the author. These come out very clearly. The book is excellent in its coverage of field theories, but is very weak in areas of condensed-matter physics. This reflects the author's own interests in the early universe. It is therefore likely to please those who are interested in modern approaches to cosmology, and may be approved of by many readers of Classical and Quantum Gravity. However, it is necessary to guard against the impression that this is all there is to theoretical physics. There are deep problems in superconductivity, for example, for which this book provides little preparation. As to level, the depth of coverage is generally greater than that required for most undergraduate programmes, although a specialist undergraduate

  18. 77 FR 51983 - Availability of Department of Energy EV Everywhere Grand Challenge Initial Framing Document and...

    Science.gov (United States)

    2012-08-28

    ... scenarios are: 1. A plug-in hybrid electric vehicle with a 40-mile all-electric range (PHEV-40) with limited...'' with the goal of enabling U.S. companies to be the first in the world to produce plug-in electric... produce plug-in electric vehicles (PEVs) that are as affordable and convenient for the average...

  19. Grand Challenges: Science, Engineering, and Societal Advances, Requiring Networking and Information Technology Research and Development

    Data.gov (United States)

    Networking and Information Technology Research and Development, Executive Office of the President — ...the U.S. Government makes critical decisions about appropriate investments in IT R and D to help society forward both socially and economically. To inform that...

  20. The Grand Challenge for Psychoanalysis – and Neuropsychoanalysis: Taking on the Game

    OpenAIRE

    Ariane eBazan

    2011-01-01

    As Ebbinghaus (1908) tells us in the opening words of his popular textbook of psychology, “psychology has a long past but only a short history.” In my opinion, there are three foundational moments in the history of psychology and, paradoxically, all three are moments of great advancement in biology. First, in the long past of psychology, psychology did not exist as such but was part of philosophy. It is extremely interesting to understand why it has been necessary, at one point of time in the...

  1. New Grand Challenge for Multimedia Information Retrieval: Bridging the Utility Gap

    NARCIS (Netherlands)

    Hanjalic, A.

    2012-01-01

    This is the author-created version of the article. The needs and expectations regarding multimedia content access have grown rapidly with the fast development of multimedia technology and the explosion of multimedia content around us. This imposed high demands on the level of sophistication of mult

  2. The scientific grand challenges of the 21st century for the Crop Science Society of America

    Science.gov (United States)

    Crop science is a highly integrative science field employing expertise from multiple disciplines to broaden our understanding of agronomic, turf, and forage crops. A major goal of crop science is to ensure an adequate and sustainable production of food, feed, fuel, and fiber for our world’s growing ...

  3. On the added value of forensic science and grand innovation challenges for the forensic community

    NARCIS (Netherlands)

    A.C. van Asten

    2014-01-01

    In this paper the insights and results are presented of a long term and ongoing improvement effort within the Netherlands Forensic Institute (NFI) to establish a valuable innovation programme. From the overall perspective of the role and use of forensic science in the criminal justice system, the co

  4. The American Academy of Social Work and Social Welfare: History and Grand Challenges

    Science.gov (United States)

    Barth, Richard P.; Gilmore, Grover C.; Flynn, Marilyn S.; Fraser, Mark W.; Brekke, John S.

    2014-01-01

    Conceptualized by social work deans and actualized with the support of major social work organizations, the American Academy of Social Work and Social Welfare was established in 2009. This article describes the historical context and creation of the Academy, whose objectives include recognizing outstanding social work scholars and practitioners;…

  5. MEASURING THE INFORMATION SOCIETY - STATE OF THE ART OF THE "GRAND CHALLENGE"

    Directory of Open Access Journals (Sweden)

    Michal Golinski

    2011-01-01

    Full Text Available The problem of measurement is the Achilles heel of the information society research. Despite, or possibly because of this reason, one can find a number of quantitative studies on the topic. In recent years, studies using composite indices gain broader media popularity. This paper presents the results of the analysis of most common composite indices used in information society research. It discusses the basic methodological issues as well as strengths and limitations of using such tools.

  6. Ocean and climate sciences taking grand challenges and extraordinary opportunities: introduction to COAA 2007 special sections

    Institute of Scientific and Technical Information of China (English)

    ZHENG Quanan; QIAO Fangli; YANG Shi-Keng

    2008-01-01

    @@ In this universe, the earth is a unique breeding ground for living beings. It bares the evolutions, sustains the survival and enriches the development of human species. The studies of history have indicated that minute changes of the earth's environment mayhave caused great impacts on the vulnerable balanced ecological systems, endanger the living conditions for human beings and associated cultures.Thus, understanding the nature's governing rules of the earth, and clarifying its fundamental laws of sciences are everlasting research topics for the human pursuits.

  7. Containing Climate Change With Black Carbon Reductions: A Grand Challenge Field Experiment

    Science.gov (United States)

    Ramanathan, V.

    2009-12-01

    The manmade greenhouse gases that are now blanketing the planet is thick enough to push the system beyond the tipping point for several elements of the climate system such as the arctic sea ice and the Himalayan-Tibetan glaciers, to name a few. Even with a targeted reduction in CO2 emission of 50% by 2050, we would still be adding more than 50 ppm of CO2 and thicken the manmade blanket by another 30%. Fortunately there are scientific ways to contain the warming and these will be outlined. But these need a truly transformational and interdisciplinary approach that brings together social scientists, natural scientists, energy experts and engineers to develop effective mitigation pathways. Towards this goal an interdisciplinary team of academics, NGOs and intergovernmental organizations from US, Europe and India have developed Project Surya to drastically decrease emissions of the major non-CO2 climate warmers (soot, methane, ozone precursor gases) from rural areas in India and China. Surya will undertake the most comprehensive data collection, to-date, on the impact of reducing biomass burning on climate forcing, health and the wellbeing of rural inhabitants most of whom live under a dollar a day. The experiment thus offers the opportunity to field test our ideas and hypotheses about the impact of black carbon and brown clouds on dimming, the Asian monsoon and the melting of the Himalayan-Tibetan glaciers. The data from this soft ‘geo-engineering’ experiment is also anticipated to lead to a sustainable way of energy consumption for the roughly 4 billion who are forced to use solid bio-fuels for all of their energy needs.

  8. CDC Grand Rounds: Addressing Preparedness Challenges for Children in Public Health Emergencies.

    Science.gov (United States)

    Hinton, Cynthia F; Griese, Stephanie E; Anderson, Michael R; Chernak, Esther; Peacock, Georgina; Thorpe, Phoebe G; Lurie, Nicole

    2015-01-01

    Recent public health emergencies including Hurricane Katrina (2005), the influenza H1N1 pandemic (2009), and the Ebola virus disease outbreak in West Africa (2014–2015) have demonstrated the importance of multiple-level emergency planning and response. An effective response requires integrating coordinated contributions from community-based health care providers, regional health care coalitions, state and local health departments, and federal agency initiatives. This is especially important when planning for the needs of children, who make up 23% of the U.S. population (1) and have unique needs that require unique planning strategies. PMID:26356838

  9. Preventing Schizophrenia and Severe Mental Illness: A Grand Challenge for Social Work

    Science.gov (United States)

    DeVylder, Jordan E.

    2016-01-01

    Schizophrenia is a leading cause of disability and health expenditure worldwide and is associated with homelessness, substance use, familial and social isolation, unemployment, involvement with the criminal justice system, stigma, and excess mortality. Prevention may be feasible through intervention with help-seeking "clinical high-risk"…

  10. FY 1992 Blue Book: Grand Challenges: High Performance Computing and Communications

    Data.gov (United States)

    Networking and Information Technology Research and Development, Executive Office of the President — High performance computing and computer communications networks are becoming increasingly important to scientific advancement, economic competition, and national...

  11. FY 1993 Blue Book: Grand Challenges 1993: High Performance Computing and Communications

    Data.gov (United States)

    Networking and Information Technology Research and Development, Executive Office of the President — High performance computing and computer communications networks are becoming increasingly important to scientific advancement, economic competition, and national...

  12. 75 FR 5634 - Grand Challenges of the 21st Century; Request for Information

    Science.gov (United States)

    2010-02-03

    ... technological advances (e.g. procurement, incentive prizes, development or adoption of technical standards, international collaboration, targeted investment in education and workforce development, sponsorship of pilots... capability, such as the development of an exaflop supercomputer capable of one million trillion...

  13. NASA ROVER, Tackling Citizen Science With Grand Challenges and Everyday Problems

    Science.gov (United States)

    Crecelius, Sarah; Chambers, Lin; Rogerson, Tina

    2015-01-01

    ROVER is the Citizen Science arm of the NASA Clouds and the Earth's Radiant Energy System (CERES) Students' Cloud Observations On-Line (S'COOL) Project. Since 2007, participants around the world have been making and reporting ground truth observations of clouds to assist in the validation of the NASA CERES satellite instrument. NASA scientists are very interested in learning how clouds affect our atmosphere, weather, and climate (relating to climate change). It is the clouds, in part, that affect the overall temperature and energy balance of the Earth. The more we know about clouds, the more we will know about our Earth as a system and citizen scientists are an important piece of that puzzle! As a ROVER cloud observer, all participants follow simple online tutorials to collect data on cloud type, height, cover and related conditions. Observations are sent to NASA to be matched to similar information obtained from satellites and sent back to participants for comparison and analysis. The supporting ROVER website houses a searchable database archiving all participant reports and matching satellite data. By involving Citizen Scientists in cloud observations and reporting we can gain a valuable set of data that would have been previously unavailable to science teams due to funding, manpower, and resource limitations or would have taken an unreasonable amount of time to collect. Reports from a wide range of Citizen Scientist locations are helpful to assess the satellite data under different conditions. With nothing more than their eyes and an internet connection participants provide a different perspective and analysis of clouds, adding to a more complete picture of what's happening in the atmosphere in which we live.

  14. Systems Pharmacology: An opinion on how to turn the impossible into grand challenges.

    Science.gov (United States)

    Westerhoff, Hans V; Nakayama, Shintaro; Mondeel, Thierry D G A; Barberis, Matteo

    2015-08-01

    A pharmacology that hits single disease-causing molecules with a single drug passively distributing to the target tissue, was almost ready. Such a pharmacology is not (going to be) effective however: a great many diseases are systems biology diseases; complex networks of some hundred thousand types of molecule, determine the functions that constitute human health, through nonlinear interactions. Malfunctions are caused by a variety of molecular failures at the same time; rarely the same variety in different individuals; in complex constellations of OR and AND logics. Few molecules cause disease single-handedly and few drugs will cure the disease all by themselves when dosed for a limited amount of time. We here discuss the implications that this discovery of the network nature of disease should have for pharmacology. We suggest ways in which pharmacokinetics, pharmacodynamics, but also systems biology and genomics may have to change so as better to deal with systems-biology diseases. PMID:26464087

  15. Biomechanical analysis technique choreographic movements (for example, "grand battman jete"

    Directory of Open Access Journals (Sweden)

    Batieieva N.P.

    2015-04-01

    Full Text Available Purpose : biomechanical analysis of the execution of choreographic movement "grand battman jete". Material : the study involved students (n = 7 of the department of classical choreography faculty of choreography. Results : biomechanical analysis of choreographic movement "grand battman jete" (classic exercise, obtained kinematic characteristics (path, velocity, acceleration, force of the center of mass (CM bio parts of the body artist (foot, shin, thigh. Built bio kinematic model (phase. The energy characteristics - mechanical work and kinetic energy units legs when performing choreographic movement "grand battman jete". Conclusions : It was found that the ability of an athlete and coach-choreographer analyze the biomechanics of movement has a positive effect on the improvement of choreographic training of qualified athletes in gymnastics (sport, art, figure skating and dance sports.

  16. Data Challenges

    CERN Multimedia

    McCubbin, N A

    Some two years ago we planned a series of Data Challenges starting at the end of 2001. At the time, that seemed to be comfortingly far in the future... Well, as the saying goes, doesn't time fly when you are having fun! ATLAS Computing is now deep in the throes of getting the first Data Challenge (DC0) up and running. One of the main aims of DC0 is to have a software 'release' in which we can generate full physics events, track all particles through the detector, simulate the detector response, reconstruct the event, and study it, with appropriate data storage en route. As all software is "always 95% ready" (!), we have been able to do most of this, more or less, for some time. But DC0 forces us to have everything working, together, at the same time: a reality check. DC0 should finish early next year, and it will be followed almost immediately afterwards by DC1 (DC0 was foreseen as the 'check' for DC1). DC1 will last into the middle of 2002, and has two major goals. The first is generation, simulation, and r...

  17. Regional economic impacts of Grand Canyon river runners.

    Science.gov (United States)

    Hjerpe, Evan E; Kim, Yeon-Su

    2007-10-01

    Economic impact analysis (EIA) of outdoor recreation can provide critical social information concerning the utilization of natural resources. Outdoor recreation and other non-consumptive uses of resources are viewed as environmentally friendly alternatives to extractive-type industries. While outdoor recreation can be an appropriate use of resources, it generates both beneficial and adverse socioeconomic impacts on rural communities. The authors used EIA to assess the regional economic impacts of rafting in Grand Canyon National Park. The Grand Canyon region of northern Arizona represents a rural US economy that is highly dependent upon tourism and recreational expenditures. The purpose of this research is twofold. The first is to ascertain the previously unknown regional economic impacts of Grand Canyon river runners. The second purpose is to examine attributes of these economic impacts in terms of regional multipliers, leakage, and types of employment created. Most of the literature on economic impacts of outdoor recreation has focused strictly on the positive economic impacts, failing to illuminate the coinciding adverse and constraining economic impacts. Examining the attributes of economic impacts can highlight deficiencies and constraints that limit the economic benefits of recreation and tourism. Regional expenditure information was obtained by surveying non-commercial boaters and commercial outfitters. The authors used IMPLAN input-output modeling to assess direct, indirect, and induced effects of Grand Canyon river runners. Multipliers were calculated for output, employment, and income. Over 22,000 people rafted on the Colorado River through Grand Canyon National Park in 2001, resulting in an estimated $21,100,000 of regional expenditures to the greater Grand Canyon economy. However, over 50% of all rafting-related expenditures were not captured by the regional economy and many of the jobs created by the rafting industry are lower-wage and seasonal. Policy

  18. Environmental Audit of the Grand Junction Projects Office

    International Nuclear Information System (INIS)

    The Grand Junction Projects Office (GJPO) is located in Mesa County, Colorado, immediately south and west of the Grand Junction city limits. The US Atomic Energy Commission (AEC) established the Colorado Raw Materials Office at the present-day Grand Junction Projects Office in 1947, to aid in the development of a viable domestic uranium industry. Activities at the site included sampling uranium concentrate; pilot-plant milling research, including testing and processing of uranium ores; and operation of a uranium mill pilot plant from 1954 to 1958. The last shipment of uranium concentrate was sent from GJPO in January, 1975. Since that time the site has been utilized to support various DOE programs, such as the former National Uranium Resource Evaluation (NURE) Program, the Uranium Mill Tailings Remedial Action Project (UMTRAP), the Surplus Facilities Management Program (SFMP), and the Technical Measurements Center (TMC). All known contamination at GJPO is believed to be the result of the past uranium milling, analyses, and storage activities. Hazards associated with the wastes impounded at GJPO include surface and ground-water contamination and potential radon and gamma-radiation exposure. This report documents the results of the Baseline Environmental Audit conducted at Grand Junction Projects Office (GJPO) located in Grand Junction, Colorado. The Grand Junction Baseline Environmental Audit was conducted from May 28 to June 12, 1991, by the Office of Environmental Audit (EH-24). This Audit evaluated environmental programs and activities at GJPO, as well as GJPO activities at the State-Owned Temporary Repository. 4 figs., 12 tabs

  19. Glen Canyon Hydropower vs. the Grand Canyon

    International Nuclear Information System (INIS)

    Many resource allocation problems currently face the hydropower industry. The current Environmental Impact Statement effort on the operation of Glen Canyon Dam is the focus of this discussion. This paper relates the process of approaching the conflict, the differing views and conflicting strategies of the parties, the emotional and logical investment of the participants, and the concerns for fairness and openness derived from the historic distrust between those with differing views. The paper is prepared from the perspective of the Bureau of Reclamation, the lead Federal agency in the effort, and the perspectives of the author who has been in a lead role in the agency's approach to the challenge. The paper describes the formulation of positions by the interested parties and the surrounding values and depth of concern exhibited in the process

  20. Grand-Mosque’ Projects in Copenhagen

    DEFF Research Database (Denmark)

    Lægaard, Sune

    2010-01-01

    concepts and values relevant to the handling of minority issues. This paper will use the concepts of tolerance and respect in relation to the Danish mosque-debate as expressed in political assemblies and public debate in two ways: It will test the applicability of the theoretical concepts and in the...... process draw out some general challenges and lessons concerning the practical applicability of these concepts. At the same time it will use the concepts as an interpretative framework to present and evaluate the actual policies regarding the distribution of public space for the building of mosques played...... out in the case. One lesson drawn from the exercise in application is that the concepts have a narrower application than often assumed and that application requires differentiation between different potential subjects of tolerance and respect....

  1. A Grand {Delta}(96) Multiplication-Sign SU(5) Flavour Model

    Energy Technology Data Exchange (ETDEWEB)

    King, Stephen F., E-mail: king@soton.ac.uk [School of Physics and Astronomy, University of Southampton, Southampton, SO17 1BJ (United Kingdom); Luhn, Christoph, E-mail: christoph.luhn@durham.ac.uk [Institute for Particle Physics Phenomenology, University of Durham, Durham, DH1 3LE (United Kingdom); Stuart, Alexander J., E-mail: a.stuart@soton.ac.uk [School of Physics and Astronomy, University of Southampton, Southampton, SO17 1BJ (United Kingdom)

    2013-02-11

    Recent results from the Daya Bay and RENO reactor experiments have measured the smallest lepton mixing angle and found it to have a value of {theta}{sub 13} Almost-Equal-To 9 Degree-Sign . This result presents a new challenge for the existing paradigms of discrete flavour symmetries which attempt to describe all quark and lepton masses and mixing angles. Here we propose a Supersymmetric Grand Unified Theory of Flavour based on {Delta}(96) Multiplication-Sign SU(5), together with a U(1) Multiplication-Sign Z{sub 3} symmetry, including a full discussion of {Delta}(96) in a convenient basis. The Grand {Delta}(96) Multiplication-Sign SU(5) Flavour Model relates the quark mixing angles and masses in the form of the Gatto-Sartori-Tonin relation and realises the Georgi-Jarlskog mass relations between the charged leptons and down-type quarks. We predict a Bi-trimaximal (not Tri-bimaximal) form of neutrino mixing matrix, which, after including charged lepton corrections with zero phase, leads to the following GUT scale predictions for the atmospheric, solar, and reactor mixing angles: {theta}{sub 23} Almost-Equal-To 36.9 Degree-Sign , {theta}{sub 12} Almost-Equal-To 32.7 Degree-Sign and {theta}{sub 13} Almost-Equal-To 9.6 Degree-Sign , in good agreement with recent global fits, and a zero Dirac CP phase {delta} Almost-Equal-To 0.

  2. Grand symmetry, spectral action and the Higgs mass

    Energy Technology Data Exchange (ETDEWEB)

    Devastato, Agostino [Dipartimento di Fisica, Università di Napoli Federico II,Monte S. Angelo, Via Cintia, 80126 Napoli (Italy); INFN, Sezione di Napoli,Monte S. Angelo, Via Cintia, 80126 Napoli (Italy); Lizzi, Fedele [Dipartimento di Fisica, Università di Napoli Federico II,Monte S. Angelo, Via Cintia, 80126 Napoli (Italy); INFN, Sezione di Napoli,Monte S. Angelo, Via Cintia, 80126 Napoli (Italy); Departament de Estructura i Constituents de la Matèria, Institut de Ciéncies del Cosmos, Universitat de Barcelona, Barcelona, Catalonia (Spain); Martinetti, Pierre [Dipartimento di Fisica, Università di Napoli Federico II,Monte S. Angelo, Via Cintia, 80126 Napoli (Italy); INFN, Sezione di Napoli,Monte S. Angelo, Via Cintia, 80126 Napoli (Italy)

    2014-01-10

    In the context of the spectral action and the noncommutative geometry approach to the standard model, we build a model based on a larger symmetry. With this grand symmetry it is natural to have the scalar field necessary to obtain the Higgs mass in the vicinity of 126 GeV. This larger symmetry mixes gauge and spin degrees of freedom without introducing extra fermions. Requiring the noncommutative space to be an almost commutative geometry (i.e. the product of manifold by a finite dimensional internal space) gives conditions for the breaking of this grand symmetry to the standard model.

  3. Lahden Grand Star Cafen mainonnan kehittäminen

    OpenAIRE

    Olkinuora, Jonne

    2008-01-01

    "Tämä työ on tutkimuksellinen opinnäytetyö, jonka toimeksiantaja on Restel Ravintolat Oy:n omistama urheiluravintola Grand Star Cafe Lahdesta. Työn tavoitteena on kehittää Grand Star Cafen mainontaa asiakaslähtöisesti. Työn tuloksena laaditaan ravintolalle mainonnan kehittämisehdotus, jonka pohjalta yrityksen on mahdollista asettaa tavoitteita mainonnalleen ja suunnitella mainostamistaan. Mainontaa käsitellään segmentoinnin ja teemaravintolan määrittelyn kautta. Mainonnan rahallista kannattav...

  4. A World of Love 2008 Music Grand Ceremony

    Institute of Scientific and Technical Information of China (English)

    Bai; Yifeng

    2008-01-01

      Under the guidance of the theme slogan of the 29th Olympic Games - One World One Dream, with dream, love and dedication as its theme, the 2008 Music Grand Ceremony & 1000 People Charity Concert on 100 days countdown to Paralympic Games is officially launched on December 22, 2007. The 2008 Music Grand Ceremony is sponsored by China Disabled Persons' Federation, and co-hosted by National Paralympic Committee of China, China Huaxia Culture Group and Beijing Hanbohongyuan Culture Development Co., Ltd., aiming at supporting Chinese paralympic delegation in the 2008 Paralympic Games.……

  5. A World of Love 2008 Music Grand Ceremony

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ Under the guidance of the theme slogan of the 29th Olympic Games - One World One Dream, with dream, love and dedication as its theme, the 2008 Music Grand Ceremony & 1000 People Charity Concert on 100 days countdown to Paralympic Games is officially launched on December 22, 2007. The 2008 Music Grand Ceremony is sponsored by China Disabled Persons' Federation, and co-hosted by National Paralympic Committee of China, China Huaxia Culture Group and Beijing Hanbohongyuan Culture Development Co., Ltd., aiming at supporting Chinese paralympic delegation in the 2008 Paralympic Games.

  6. 峡谷雕刻家Grand Cherokee

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    @@ "一个极好的峡谷雕刻家"这是美国一家有名的汽车出版物对Grand Cherokee的评价.为什么不是呢?六十年来,我们的工程师正在完善吉普发动机系统,四轮驱动系统,悬挂和刹车部分,Grand Cherokee标准的Quadrarac Ⅱ分动箱,是目前最先进的分动箱之一,使得四轮驱动的卓越性能不断得以延续.

  7. Grand symmetry, spectral action and the Higgs mass

    International Nuclear Information System (INIS)

    In the context of the spectral action and the noncommutative geometry approach to the standard model, we build a model based on a larger symmetry. With this grand symmetry it is natural to have the scalar field necessary to obtain the Higgs mass in the vicinity of 126 GeV. This larger symmetry mixes gauge and spin degrees of freedom without introducing extra fermions. Requiring the noncommutative space to be an almost commutative geometry (i.e. the product of manifold by a finite dimensional internal space) gives conditions for the breaking of this grand symmetry to the standard model

  8. The Grand Geochemistry of 4 Vesta: First Results

    Science.gov (United States)

    Prettyman, T. H.; Beck, A.; Feldman, W. C.; Forni, O.; Joy, S. P.; Lawrence, D. J.; McCoy T. J.; McFadden, L. A.; McSween, H. Y.; Mittlefehldt, D. W.; Polanskey, C. A.; Rayman, M. D.; Raymond, C. A.; Reedy, R. C.; Russell, C. T.; Titus, T. N.; Toplis, M. J.; Yamashita, N.

    2012-01-01

    On 12-Dec-2011, the Dawn spacecraft commenced low altitude mapping of the giant asteroid, 4 Vesta (264-km mean radius). Dawn's roughly circular, polar, low altitude mapping orbit (LAMO) has a mean radius of 470 km, placing the spacecraft within about 210 km of Vesta's surface. At these altitudes, Dawn s Gamma Ray and Neutron Detector (GRaND) is sensitive to Vesta's elemental com-position (Fig. 1). GRaND will acquire data in LAMO for up to 16 weeks, which is sufficient to map the elemental composition of the entire surface of Vesta. The timing of LAMO enables us to report the first results of our geochemistry investigation at this conference. In this abstract, we present an overview of our initial observations, based on data acquired at high altitude and during the first weeks of LAMO. GRaND overview. A detailed description of the GRaND instrument, science objectives and prospective results is given in [1]. At low altitudes, GRaND is sensitive to gamma rays and neutrons produced by cosmogenic nuclear reactions and radioactive decay occurring within the top few decimeters of the surface and on a spatial scale of a few hundred kilometers. From these nuclear emissions, the abundance of several major- and minor-elements, such as Fe, Mg, Si, K, and Th can be determined. Assuming the howardite, eucrite, and diogenite (HED) meteorites are representative of Vesta s crustal composition [2], then GRaND will be able to map the mixing ratios of whole-rock HED end-members, enabling the determination of the relative proportions of basaltic eucrite, cumulate eucrite, and diogenite as well as the proportions of mafic and plagioclase minerals [1,3]. GRaND will also search for compositions not well-represented in the meteorite collection, such as evolved, K-rich lithologies [4], and outcrops of olivine from Vesta s mantle or igneous intrusions in major impact basins [5]. The search for a possible mesosiderite source region is described in [6]. GRaND will globally map the abundance of

  9. SPS Challenges

    CERN Document Server

    Chapochnikova, Elena

    2008-01-01

    In future the SPS should be able to transfer to the LHC the beam produced by a completely new pre-injector chain and required by the LHC for different upgrade scenarios. The issues related to this extremely challenging task are presented together with some possible ways of overcoming the problems that arise. Besides an increase in injection energy provided by PS2, these measures can include both an SPS vacuum chamber upgrade against the e-cloud and operation with larger longitudinal emittance for beam stability. As a result the power plant of the SPS RF system must be doubled. The SPS upgrade will also need the improvement or replacement of many other machine elements.

  10. La Grande Guerra fra realtà ed illusione: La Grande Illusion e l’immaginario

    Directory of Open Access Journals (Sweden)

    Simone Di Blasi

    2015-12-01

    Full Text Available The aim of this brief essay is to focus on the relation between the meaning of reality and illusion in the movie La Grande Illusion (1937 by Jean Renoir and therefore to find how these ideas of the author may be productive in a thought about the imaginary. After a short look on the movies made at that time on the First World War, there is an overview of the French director poetics, which redefines the conception of the realism, contextualizing its work at the point of convergence of two imaginary “technological lines”, the cinema and the aviation. It follows the analysis of the movie and the illusions, as social largely shared imaginaries, described by the author. In the end it is showed the importance and the of illusion in Renoir’s poetics. Beyond the relationship realityfiction, he thought a dynamic reciprocity among illusion and reality: so that the reality is as “illusion” (a ruled horizon in which it is possible to enjoy a world of play and the illusion as an activity creating contents of “reality”.

  11. The spectrum of high-energy cosmic rays measured with KASCADE-Grande

    CERN Document Server

    Apel, W D; Bekk, K; Bertaina, M; Bluemer, J; Bozdog, H; Brancus, I M; Buchholz, P; Cantoni, E; Chiavassa, A; Cossavella, F; Daumiller, K; de Souza, V; Di Pierro, F; Doll, P; Engel, R; Engler, J; Finger, M; Fuhrmann, D; Ghia, P L; Gils, H J; Glasstetter, R; Grupen, C; Haungs, A; Heck, D; Hoerandel, J R; Huber, D; Huege, T; Kampert, K -H; Kang, D; Kickelbick, D; Klages, H O; Link, K; Luczak, P; Ludwig, M; Mathes, H J; Mayer, H J; Melissas, M; Milke, J; Mitrica, B; Morello, C; Navarra, G; Oehlschlaeger, J; Ostapchenko, S; Over, S; Palmieri, N; Petcu, M; Pierog, T; Rebel, H; Roth, M; Schieler, H; Schroeder, F G; Sima, O; Toma, G; Trinchero, G C; Ulrich, H; Weindl, A; Wochele, J; Wommer, M; Zabierowski, J

    2012-01-01

    The energy spectrum of cosmic rays between 10**16 eV and 10**18 eV, derived from measurements of the shower size (total number of charged particles) and the total muon number of extensive air showers by the KASCADE-Grande experiment, is described. The resulting all-particle energy spectrum exhibits strong hints for a hardening of the spectrum at approximately 2x10**16 eV and a significant steepening at c. 8x10**16 eV. These observations challenge the view that the spectrum is a single power law between knee and ankle. Possible scenarios generating such features are discussed in terms of astrophysical processes that may explain the transition region from galactic to extragalactic origin of cosmic rays.

  12. An international borderland of concern: Conservation of biodiversity in the Lower Rio Grande Valley

    Science.gov (United States)

    Leslie,, David M., Jr.

    2016-01-01

    The Lower Rio Grande Valley (LRGV) of southern Texas is located on the United States-Mexico borderland and represents a 240-kilometer (150-mile) linear stretch that ends at the Gulf of Mexico. The LRGV represents a unique transition between temperate and tropical conditions and, as such, sustains an exceptionally high diversity of plants and animals—some of them found in few, or no other, places in the United States. Examples include Leopardus pardalis albescens (northern ocelot) and Falco femoralis septentrionalis (northern aplomado falcon)—both endangered in the United States and emblematic of the LRGV. The U.S. Fish and Wildlife Service (USFWS) manages three national wildlife refuges (Santa Ana, Lower Rio Grande Valley, and Laguna Atascosa) that together make up the South Texas Refuge Complex, which actively conserves biodiversity in about 76,006 hectares (187,815.5 acres) of native riparian and upland habitats in the LRGV. These diminished habitats harbor many rare, threatened, and endangered species. This report updates the widely used 1988 USFWS biological report titled “Tamaulipan Brushland of the Lower Rio Grande Valley of South Texas: Description, Human Impacts, and Management Options” by synthesizing nearly 400 peer-reviewed scientific publications that have resulted from biological and sociological research conducted specifically in the four Texas counties of the LRGV in the past nearly 30 years. This report has three goals: (1) synthesize scientific insights gained since 1988 related to the biology and management of the LRGV and its unique biota, focusing on flora and fauna of greatest conservation concern; (2) update ongoing challenges facing Federal and State agencies and organizations that focus on conservation or key natural resources in the LRGV; and (3) redefine conservation opportunities and land-acquisition strategies that are feasible and appropriate today, given the many new and expanding constraints that challenge conservation

  13. Accidental permutation symmetries as a test for Grand Unification: the supersymmetric $SU(5)$ case

    CERN Document Server

    Fichet, Sylvain

    2016-01-01

    Unification of matter fields implies the existence of accidental permutation symmetries, which potentially remain immune to large quantum corrections up to the TeV scale. We investigate the case of a supersymmetric $SU(5)$ grand unified theory, where such a permutation symmetry is present in the up-type squark sector. We present a variety of tests allowing to challenge the $SU(5)$ hypothesis based on the observation of squarks at the LHC. These tests appear as relations among observables involving flavour-violating or chirality-flipping decays of squarks. Moreover, they rely on top-polarimetry and charm-tagging. As an example, we discuss the application to the scenario of Natural Supersymmetry, while more examples can be found in the related journal publications.

  14. NewsMars: Express journey to Mars ASE 2003: Knocked out by meteorites Events: Sun-Earth Day ASE 2003: Fun Physics - popular as ever Appointments: Sykes to bring science to the people UK Science Education: The future's bright, the future's science ASE 2003: A grand finale for Catherine Teaching Resources: UK goes to the planets Cambridge Physics Update: Basement physics Conferences: Earth Science Teachers' Association Conference 2003 New Website: JESEI sets sail GIREP: Teacher education seminar Malaysia: Rewards for curriculum change Cambridge Physics Update: My boomerang will come back! Teaching Resources: Widening particiption through ideas and evidence with the University of Surrey Wales: First Ffiseg Events: Nuna: Solar car on tour Physics on Stage: Physics on Stage 3 embraces life Symposium: In what sense a nuclear 'debate'? Gifted and Talented: Able pupils experiencing challenging science Australia: ISS flies high Down Under

    Science.gov (United States)

    2003-03-01

    Mars: Express journey to Mars ASE 2003: Knocked out by meteorites Events: Sun-Earth Day ASE 2003: Fun Physics - popular as ever Appointments: Sykes to bring science to the people UK Science Education: The future's bright, the future's science ASE 2003: A grand finale for Catherine Teaching Resources: UK goes to the planets Cambridge Physics Update: Basement physics Conferences: Earth Science Teachers' Association Conference 2003 New Website: JESEI sets sail GIREP: Teacher education seminar Malaysia: Rewards for curriculum change Cambridge Physics Update: My boomerang will come back! Teaching Resources: Widening particiption through ideas and evidence with the University of Surrey Wales: First Ffiseg Events: Nuna: Solar car on tour Physics on Stage: Physics on Stage 3 embraces life Symposium: In what sense a nuclear 'debate'? Gifted and Talented: Able pupils experiencing challenging science Australia: ISS flies high Down Under

  15. Radiatively Induced Fermi Scale in Grand Unified Theories

    CERN Document Server

    Alanne, Tommi; Sannino, Francesco; Tuominen, Kimmo

    2015-01-01

    We consider Grand Unified Theories in which the hierarchy between the unification and the Fermi scale emerges radiatively. Within the Pati-Salam framework, we show that it is possible to construct a viable model where the Higgs is an elementary pseudo-Goldstone boson, and the correct hierarchy is generated.

  16. Carbonaceous aerosol particles from common vegetation in the Grand Canyon

    Energy Technology Data Exchange (ETDEWEB)

    Hallock, K.A.; Mazurek, M.A. [Brookhaven National Lab., Upton, NY (United States); Cass, G.R. [California Inst. of Tech., Pasadena, CA (United States). Dept. of Environmental Engineering Science

    1992-05-01

    The problem of visibility reduction in the Grand Canyon due to fine organic aerosol particles in the atmosphere has become an area of increased environmental concern. Aerosol particles can be derived from many emission sources. In this report, we focus on identifying organic aerosols derived from common vegetation in the Grand Canyon. These aerosols are expected to be significant contributors to the total atmospheric organic aerosol content. Aerosol samples from living vegetation were collected by resuspension of surface wax and resin components liberated from the leaves of vegetation common to areas of the Grand Canyon. The samples were analyzed using high-resolution gas chromatography/mass spectrometry (GC/MS). Probable identification of compounds was made by comparison of sample spectra with National Institute of Standards and Technology (NIST) mass spectral references and positive identification of compounds was made when possible by comparison with authentic standards as well as NIST references. Using these references, we have been able to positively identify the presence of n-alkane and n-alkanoic acid homolog series in the surface waxes of the vegetation sampled. Several monoterpenes, sesquiterpenes, and diterpenes were identified also as possible biogenic aerosols which may contribute to the total organic aerosol abundance leading to visibility reduction in the Grand Canyon.

  17. Os grandes consumidores de consultas medicas: um estudo de familia

    Directory of Open Access Journals (Sweden)

    M. Pereira Graça

    2002-01-01

    Full Text Available Este artículo describe un estudio sobre algunas características familiares de sujetos grandes consumidores de servicios de salud. Por un lado, se compara un grupo de grandes consumidores de servicios de salud, a nivel de número de consultas, con un grupo control en términos de funcionamiento familiar y actitudes hacia los médicos y la Medicina; por otro lado, se estudia la relación entre la dinámica familiar y las actitudes hacia la Medicina y los médicos en el grupo de los grandes consumidores. Los resultados muestran que los dos grupos de usuarios son significativamente diferentes; además, en el grupo de grandes consumidores el funcionamiento familiar problemático parece ser un factor intermediario en el desarrollo de actitudes menos negativas hacia los médicos y la Medicina. Se discuten las implicaciones que los resultados tienen a nivel de intervención terapéutica.

  18. Cyber Resilience in de Bestuurskamer : The Grand Conference in Amsterdam

    NARCIS (Netherlands)

    Klaver, M.H.A.

    2013-01-01

    Op 16 oktober 2012 vond in Amsterdam The Grand Conference plaats. Deze conferentie werd georganiseerd door het Centre for the Protection of National lnfrastructure (CPNI.NL) in nauwe samenwerking met de Europese Commissie, de Europese Networkand Information Security Agency (ENISA), het Amerikaanse D

  19. Lectures - Les grandes théories du nationalisme

    OpenAIRE

    Jaffrelot, Christophe

    2002-01-01

    Ce livre a pour ambition de classer les grandes théories du nationalisme selon deux axes qui opposent, pour l’un, un « principe de domination » à un « principe de cohésion », pour l’autre les « évolutions structurelles » aux « stratégies d’acteurs » (...).

  20. Grande Ronde Basin Fish Habitat Enhancement Project : 1998 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    McGowan, Vance R.; Powell, Russ M.

    1999-05-01

    The primary goal of ''The Grande Ronde Basin Fish Habitat Improvement Project'' is to access, create, improve, protect, and restore reparian and instream habitat for anadromous salmonids, thereby maximizing opportunities for natural fish production within the basin.

  1. Carbonaceous aerosol particles from common vegetation in the Grand Canyon

    International Nuclear Information System (INIS)

    The problem of visibility reduction in the Grand Canyon due to fine organic aerosol particles in the atmosphere has become an area of increased environmental concern. Aerosol particles can be derived from many emission sources. In this report, we focus on identifying organic aerosols derived from common vegetation in the Grand Canyon. These aerosols are expected to be significant contributors to the total atmospheric organic aerosol content. Aerosol samples from living vegetation were collected by resuspension of surface wax and resin components liberated from the leaves of vegetation common to areas of the Grand Canyon. The samples were analyzed using high-resolution gas chromatography/mass spectrometry (GC/MS). Probable identification of compounds was made by comparison of sample spectra with National Institute of Standards and Technology (NIST) mass spectral references and positive identification of compounds was made when possible by comparison with authentic standards as well as NIST references. Using these references, we have been able to positively identify the presence of n-alkane and n-alkanoic acid homolog series in the surface waxes of the vegetation sampled. Several monoterpenes, sesquiterpenes, and diterpenes were identified also as possible biogenic aerosols which may contribute to the total organic aerosol abundance leading to visibility reduction in the Grand Canyon

  2. Scrapheap Challenge

    CERN Multimedia

    2004-01-01

    Three British guys at CERN recently took a break from work to try their hand at Scrapheap Challenge. Shown on Channel 4 in the UK, it is a show where two teams must construct a machine for a specific task using only the junk they can scavenge from the scrap yard around them. And they have just 10 hours to build their contraption before it is put to the test. The first round, aired 19 September, pitted a team of three women, from the British Army's Royal Electrical and Mechanical Engineers, against the CERN guys - the Up 'n Atoms: Ali Day, David McFarlane and James Ridewood. Each team, with the help of an appointed expert, had the task of making a giant, 3-metre self-propelled "bowling ball", to roll down a 50 metre bowling alley at skittles 4 metres high. The Up 'n Atoms' contraption featured a small car with a huge wheel on its back. Once up to speed, slamming on the brakes caused the wheel to roll over and take the car with it. On their very last run they managed to take out seven pins. Luckily, though, ...

  3. 75 FR 61173 - Jackson Hole Airport Agreement Extension, Final Environmental Impact Statement, Grand Teton...

    Science.gov (United States)

    2010-10-04

    ... National Park Service Jackson Hole Airport Agreement Extension, Final Environmental Impact Statement, Grand... of Availability of the Final Environmental Impact Statement for the Jackson Hole Airport Agreement... Impact Statement for the Jackson Hole Airport Agreement Extension, Grand Teton National Park,...

  4. 75 FR 11938 - Meridian Automotive Systems, Grand Rapids, MI; Notice of Termination of Investigation

    Science.gov (United States)

    2010-03-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR Employment and Training Administration Meridian Automotive Systems, Grand Rapids, MI; Notice of Termination... Meridian Automotive Systems, Grand Rapids, Michigan (Meridian Automotive). The petitioning group of...

  5. Energetic challenges

    International Nuclear Information System (INIS)

    Full text: Connecting the 2 billion people who have no access to commercial energy is the most important energy challenge facing the world community. Women and children, primarily in developing countries, spend their days collecting wood or cow dung for fuel for cooking and heating their homes in very inefficient stoves: this both harms the environment and directly threatens the health of their families. Outmoded boilers linked to central heating systems in most of the cities of Eastern Europe and the former Soviet Union pose another challenge. They are inefficient; they lack modern pollution control; and the end use of the heat is not metered, leading to more inefficiency and waste. Both of these problems cry out to the world for investment. Investing in energy solutions in these countries can bring about significant and immediate local environmental improvements, achieve greatly improved energy efficiency, and substantially reduce greenhouse gas emissions. But, energy and environmental policy tends to direct investment towards industrial countries, even though it would have a greater impact on the environment - not to mention the human condition in general - in the developing countries and transition economies. We need a new direction in energy policy. The World Energy Council has studied the needs and we believe a number of our proposed policy recommendations would lead towards greater investment in the countries where it is most needed. The political risk of key energy project investments must be addressed both by the countries seeking outside investment and by the global community at large. The countries must create an investor-friendly climate, which includes the rule of law and recognizes private property rights. The global community can contribute by developing new political risk insurance schemes rewarding the countries that create this climate. Energy must be priced to cover costs and ensure payment. In too many countries, blanket subsidies for energy

  6. Regulatory challenges

    International Nuclear Information System (INIS)

    The problem for policy makers wanting to liberalize natural gas markets is that its concentrated structure may also be the socially most efficient one. Because of scale economies, more firms operating in the market may incur higher transportation costs unless the market grows sufficiently in each geographic segment. This argument goes for product extension through vertical (or horizontal) integration and the exploitation of economies of scope as well. Thus, the challenge for governments is to intervene in a way that preserves a market structure that has the potential to minimize cost, and at the same lime change its behavior in order to avoid possible lax cost control and exploitation of market power. The existence of scope advantages indicates that liberalization of the market should open for the possibility to bundle services in competition with provision of unbundled services. If operations are unbundled and there exist economies of scope, the gain from increased competition should be weighed against the losses of less efficient operations of each firm. Thus, with the growth in the European market, gradually more arguments support the idea of unbundling. The significant scale economy in trunk pipelines, sunk investments and capital immobility, possible economies of scope in vertical integration and companies' bundling of services influences vertical and horizontal ownership relations and contractual terms in the European gas market. In specific segments of the markets, these relationships may promote efficient investments and pricing without public interference, but the strong concentration of market power indicates that this is rather the exception than the rule. In order to design an efficient and welfare maximizing way of regulating the market one needs a closer identification of the actual goal of the regulation. Microeconomic theory is often used for this purpose. The author discusses the alternatives of laissez-faire, nationalization or regulation for the

  7. Energy challenges

    International Nuclear Information System (INIS)

    Satisfying the world's insatiable appetite for fuel without destroying the environment is the biggest challenge facing the energy industry. World energy consumption is expected to soar by 50% to a staggering 180 000 GW h per year by 2020, with the developing world demanding an ever-increasing share. Although oil and natural-gas reserves will last for several more decades, environmental concerns are increasingly dominating the agenda. Last year 178 countries agreed to a watered-down version of the original Kyoto protocol, which was designed to reduce the emissions of greenhouse gases from industrialized countries by an average of 5.2% below 1990 levels. Under the new agreement, dubbed 'Kyoto lite' by environmentalists, emissions will be cut by just 2%. The relaxed targets are still not enough to convince the US, the world's biggest polluter, to sign the Kyoto treaty. Renewable technologies still make up less than 1% of the world's commercial energy. Distributed power is also likely to emerge from the development of fuel cells - devices that convert the chemical energy of hydrogen and oxygen directly into electricity, with only water as a by-product. The move away from carbon-based fossil fuels to hydrogen is also driving the hydrogen economy. A longer-term possibility is nuclear fusion. Despite the enormous progress in the performance of experiments over the past 30 years, nuclear fusion is still decades away from generating electricity. Advocates of fusion power claim that it could be a safe and sustainable source of energy that does not produce any greenhouse gases or long-lived nuclear waste. However, physicists have still to demonstrate that the energy produced by the fusion of deuterium and tritium can be sustained. Advances in physics and engineering are making energy from renewable sources increasingly affordable. But political will - as well as scientific progress - is just as crucial for safeguarding the environment for generations to come

  8. Birds of the Reserva Biológica do Mato Grande and surroundings, Rio Grande do Sul, Brazil

    DEFF Research Database (Denmark)

    Vizentin-Bugoni, Jeferson; Jacobs, Fernando; Coimbra, Marco Antônio Afonso;

    2015-01-01

    The Reserva Biológica do Mato Grande encompasses 5,161 hectares of wetlands, restinga forests and grasslands in southern Brazil. Aiming to assemble a list of bird species occurring in the reserve, we carried out 21 monthly expeditions from July 2007 to March 2009 and an additional visit on October...

  9. Overview of natural gas in Rio Grande do Norte, Brazil; Panorama do gas natural no Rio Grande do Norte

    Energy Technology Data Exchange (ETDEWEB)

    Teixeira, Pedro Helio Gomes [Universidade Federal do Rio Grande do Norte (GREEN/UFRN), Natal, RN (Brazil). Centro de Tecnologia. Grupo de Estudos Energeticos

    2008-07-01

    This work draws a picture of what the natural gas means to Rio Grande do Norte in its quantitative dimension, expressed in the numbers and reserve indicators, production and structure of consume. In another dimension, it broaches the processes of energetic substitution by the natural gas in the state energetic matrix. (author)

  10. 78 FR 26807 - Vista Grande Drainage Basin Improvement Project, Fort Funston, Golden Gate National Recreation...

    Science.gov (United States)

    2013-05-08

    ... Recreation Area, San Francisco County, CA AGENCY: National Park Service, Interior. ACTION: Notice of Intent... National Recreation Area (GGNRA). The Vista Grande Tunnel connects the Vista Grande watershed to an outfall..., Golden Gate National Recreation Area; Attn: Vista Grande Project; Fort Mason, Building 201, San...

  11. 76 FR 9341 - Grand River Dam Authority; Notice of Application Accepted for Filing, Soliciting Comments...

    Science.gov (United States)

    2011-02-17

    ..., 2011. d. Applicant: Grand River Dam Authority (GRDA). e. Name of Project: Pensacola Project. f. Location: Grand (Neosho) River in Craig, Delaware, Mayes, and Ottawa Counties, Oklahoma. g. Filed Pursuant... Federal Energy Regulatory Commission Grand River Dam Authority; Notice of Application Accepted for...

  12. Rethinking and Reconstruction on Animal Welfare in Experiments of Bioscience%生命科学实验中动物福利问题的反思与重构——基于生态哲学视角

    Institute of Scientific and Technical Information of China (English)

    朱玉芳

    2011-01-01

    针对目前生命科学实验中学生排斥使用实验动物的现象,反思并分析了过度关注动物福利的原因,并在解读生态哲学思想的基础上重构了实验中动物福利问题,旨在为高校的生命科学实验的顺利进行提供启示和借鉴.%At present,according to the phenomenon that students reject experimenting on animal in experiments of bioscience.the article reflects on and analyses the reasons for paying excessive attention to animal welfare,and on the basis of interpreting ecological philosophy,it rebuild the view of animal welfare in experiment,aiming at providing enlightenment and experience for carrying on biological science experiment successfully in college.

  13. Water Environment Evolution along the China Grand Canal

    Science.gov (United States)

    Mao, F.; Wu, Y. X.; Yang, B. F.; Li, X. J.

    2014-03-01

    The China Grand Canal is one of the earliest canals in the world, having lasted for nearly 3000 years. Even its section canals have a rich history, such as the North-South Grand Canal that was established during the Sui Dynasty, whereas the Beijing-Hangzhou Canal was excavated during the Yuan Dynasty and the east line of the South-to-North Water Diversion. As one of the longest in the world, the China Grand Canal's total length is over 3500 kilometers. This length includes the navigable, unnavigable, and underground sections. Making the best use of situations and according to local conditions, the Chinese people harmoniously constructed the Beijing-Hangzhou Canal with nature. Tens of millions of workers took nearly 3000 years to complete the great shipping system. Navigable sections still exist for up to 900 kilometers and the volume of freight traffic is approximately 300 million tons. The canal remains the main logistical channel of the North-to-South Coal Transportation, South-to-North Water Diversion, and resources circulation. To date, China is promoting the success of heritage application. Part of these efforts is the declaration of the China Grand Canal as a World Cultural Heritage by 2014. In addition, the east route of the South-to-North Water Transfer project is planned to be navigable by 2016. The ancient Beijing-Hangzhou Grand Canal will usher in the new ecological civilization and cultural revival along the canal. This paper presents technical methods of water environment evolution research on the river system, river, and water quality along the Beijing-Hangzhou Canal through the integration of historical literature and modern remote sensing image data. The study carried out water environment investigation and analysis along the Beijing-Hangzhou canal by using ETM, SPOT image data, and GPS measurement data. Spatial and temporal evolution characteristics and regulations of the Beijing-Hangzhou Grand Canal regional water environment in the span of 3000

  14. Water Environment Evolution along the China Grand Canal

    International Nuclear Information System (INIS)

    The China Grand Canal is one of the earliest canals in the world, having lasted for nearly 3000 years. Even its section canals have a rich history, such as the North-South Grand Canal that was established during the Sui Dynasty, whereas the Beijing-Hangzhou Canal was excavated during the Yuan Dynasty and the east line of the South-to-North Water Diversion. As one of the longest in the world, the China Grand Canal's total length is over 3500 kilometers. This length includes the navigable, unnavigable, and underground sections. Making the best use of situations and according to local conditions, the Chinese people harmoniously constructed the Beijing-Hangzhou Canal with nature. Tens of millions of workers took nearly 3000 years to complete the great shipping system. Navigable sections still exist for up to 900 kilometers and the volume of freight traffic is approximately 300 million tons. The canal remains the main logistical channel of the North-to-South Coal Transportation, South-to-North Water Diversion, and resources circulation. To date, China is promoting the success of heritage application. Part of these efforts is the declaration of the China Grand Canal as a World Cultural Heritage by 2014. In addition, the east route of the South-to-North Water Transfer project is planned to be navigable by 2016. The ancient Beijing-Hangzhou Grand Canal will usher in the new ecological civilization and cultural revival along the canal. This paper presents technical methods of water environment evolution research on the river system, river, and water quality along the Beijing-Hangzhou Canal through the integration of historical literature and modern remote sensing image data. The study carried out water environment investigation and analysis along the Beijing-Hangzhou canal by using ETM, SPOT image data, and GPS measurement data. Spatial and temporal evolution characteristics and regulations of the Beijing-Hangzhou Grand Canal regional water environment in the span of

  15. High-energy cosmic rays measured with KASCADE-Grande

    CERN Document Server

    Haungs, A; Arteaga-Velazquez, J C; Bekk, K; Bertaina, M; Bluemer, J; Bozdog, H; Brancus, I M; Cantoni, E; Chiavassa, A; Cossavella, F; Curcio, C; Daumiller, K; de Souza, V; Di Pierro, F; Doll, P; Engel, R; Engler, J; Fuchs, B; Fuhrmann, D; Gils, H J; Glasstetter, R; Grupen, C; Heck, D; Hoerandel, J R; Huber, D; Huege, T; Kampert, K -H; Kang, D; Klages, H O; Link, K; Luczak, P; Ludwig, M; Mathes, H J; Mayer, H J; Melissas, M; Milke, J; Mitrica, B; Morello, C; Oehlschlaeger, J; Ostapchenko, S; Palmieri, N; Petcu, M; Pierog, T; Rebel, H; Roth, M; Schieler, H; Schoo, S; Schroeder, F G; Sima, O; Toma, G; Trinchero, G C; Ulrich, H; Weindl, A; Wochele, D; Wochele, J

    2013-01-01

    The detection of high-energy cosmic rays above a few hundred TeV is realized by the observation of extensive air-showers. By using the multi-detector setup of KASCADE-Grande, energy spectrum, elemental composition, and anisotropies of high-energy cosmic rays in the energy range from below the knee up to 2 EeV are investigated. In addition, the large high-quality data set permits distinct tests of the validity of hadronic interaction models used in interpreting air-shower measurements. After more than 16 years, the KASCADE-Grande experiment terminated measurements end of 2012. This contribution will give an overview of the main results of the data analysis achieved so far, and will report about the status of KCDC, the KASCADE Cosmic-ray Data Center, where via a web-based interface the data will be made available for the interested public.

  16. City of Grand Rapids Building Solar Roof Demonstration

    Energy Technology Data Exchange (ETDEWEB)

    DeClercq, Mark; Martinez, Imelda

    2012-08-31

    Grand Rapids, Michigan is striving to reduce it environmental footprint. The municipal government organization has established environmental sustainability policies with the goal of securing 100% of its energy from renewable sources by 2020. This report describes the process by which the City of Grand Rapids evaluated, selected and installed solar panels on the Water/Environmental Services Building. The solar panels are the first to be placed on a municipal building. Its new power monitoring system provides output data to assess energy efficiency and utilization. It is expected to generate enough clean solar energy to power 25 percent of the building. The benefit to the public includes the economic savings from reduced operational costs for the building; an improved environmentally sustainable area in which to live and work; and increased knowledge about the use of solar energy. It will serve as a model for future energy saving applications.

  17. The Origin of Families and $SO(18)$ Grand Unification

    CERN Document Server

    BenTov, Yoni

    2015-01-01

    We exploit a recent advance in the study of topological superconductors to propose a solution to the nagging family puzzle of particle physics in the context of SO(18) (or more correctly, Spin(18)) grand unification. We argue that Yukawa couplings of intermediate strength may allow the mirror matter and extra families to decouple at arbitrarily high energies. As was clear from the existing literature, we have to go beyond the Higgs mechanism in order to solve the family puzzle. A pattern of symmetry breaking which results in the SU(5) grand unified theory with horizontal or family symmetry USp(4) = Spin(5) (or more loosely, SO(5)) leaves exactly three light families of matter and seems particularly appealing. We comment briefly on an alternative scheme involving discrete non-abelian family symmetries. In a few lengthy appendices we review some of the pertinent condensed matter theory.

  18. Isotopic Grand Unification with the inclusion of gravity

    CERN Document Server

    Santilli, R M

    1997-01-01

    We introduce a dual lifting of unified gauge theories, the first characterized by the {\\it isotopies}, which are axiom- preserving maps into broader structure with positive-definite generalized units used for the representation of matter under the isotopies of the Poincare' symmetry, and the second characterized by the {\\it isodualities}, which are anti-isomorphic maps with negative-definite generalized units used for the representation of antimatter under the isodualities of the Poimcare' symmetry. We then submit, apparently for the first time, a novel grand unification with the inclusion of gravity for matter embedded in the generalized positive-definite units of unified gauge theories while gravity for antimatter is embedded in the isodual isounit. We then show that the proposed grand unification provides realistic possibilities for a resolution of the axiomatuic incompatibilities between graviitation and electroweak interactions due to curvature, antimatter and the fundamental space-time symmetries.

  19. Late archaic settlement systems in the northern Rio Grande

    Energy Technology Data Exchange (ETDEWEB)

    Vierra, Bradley J.

    2003-01-01

    Last year at these meetings I proposed a possible seasonal transhumance pattern for the Late Archaic in the northern Rio Grande region. This pattern involved the movement of groups from the lowland juniper-savanna grasslands in the early summer, to the upland ponderosa pindmixed conifer forests in the mid to late summer, and then back down to the piiion-juniper woodlands during the fall. The Rio Grande Valley was also used for winter habitation sites. Following on this research, I take the next step by studying the inter-assemblage variability represented in a sample of open-air sites located within each of these vegetation communities. The results indicate that there are significant differences in reduction tactics represented between valley habitation vs., upland campsites, and that these site sites are linked together by obsidian procurement patterns.

  20. Origin of families and S O (18 ) grand unification

    Science.gov (United States)

    BenTov, Yoni; Zee, A.

    2016-03-01

    We exploit a recent advance in the study of interacting topological superconductors to propose a solution to the family puzzle of particle physics in the context of S O (18 ) [or more correctly, Spin(18 )] grand unification. We argue that Yukawa couplings of intermediate strength may allow the mirror matter and extra families to decouple at arbitrarily high energies. As was clear from the existing literature, we have to go beyond the Higgs mechanism in order to solve the family puzzle. A pattern of symmetry breaking which results in the S U (5 ) grand unified theory with horizontal or family symmetry U S p (4 )=Spin(5 ) [or more loosely, S O (5 )] leaves exactly three light families of matter and seems particularly appealing. We comment briefly on an alternative scheme involving discrete non-Abelian family symmetries. In a few lengthy Appendices we review some of the pertinent condensed matter theory.

  1. Departure from Weinberg-Salem model and Grand Unification

    International Nuclear Information System (INIS)

    The spontaneous symmetry breakdown of Grand Unified Groups like SO(10) can lead to an extra U(1) group beyond the SU(2) x U(1) of Weinberg-Salam. The neutral current data in such models could depend on three new parameters beyond the two in the standard model. However, grand unification imposes restriction on coupling constants limiting the analysis to two new parameters. Further, only one new parameter occurs in neutrino-scattering data. More accurate data can thus be used in the future to set limits on these parameters. The present data when used with the more general parametrization no longer determines the value of sin2 theta/sub w/ as accurately. This leads to a greater uncertainty in the estimate of the proton lifetime

  2. Clinical Immersion and Biomedical Engineering Design Education: "Engineering Grand Rounds".

    Science.gov (United States)

    Walker, Matthew; Churchwell, André L

    2016-03-01

    Grand Rounds is a ritual of medical education and inpatient care comprised of presenting the medical problems and treatment of a patient to an audience of physicians, residents, and medical students. Traditionally, the patient would be in attendance for the presentation and would answer questions. Grand Rounds has evolved considerably over the years with most sessions being didactic-rarely having a patient present (although, in some instances, an actor will portray the patient). Other members of the team, such as nurses, nurse practitioners, and biomedical engineers, are not traditionally involved in the formal teaching process. In this study we examine the rapid ideation in a clinical setting to forge a system of cross talk between engineers and physicians as a steady state at the praxis of ideation and implementation. PMID:26857015

  3. Desert grand unified theories and new light degrees of freedom

    International Nuclear Information System (INIS)

    We show that by introducing additional degrees of freedom with masses of the order of the electroweak scale the usual predictions for the proton lifetime and sin2θW obtained in the contexts of grand-unified-theory models with deserts can now be made to agree with current experimental data. We tabulate a number of possible quantum number assignments for these new particles

  4. Symposium: Optics Along The Rio Grande Research Corridor

    Science.gov (United States)

    Freese, K.

    1985-11-01

    New Mexico's scientific, technological, and educational resources are concentrated along a 300-mile stretch of the Rio Grande, from Los Alamos in the north to Las Cruces in the south. This area contains two major multidisciplinary national laboratories (Los Alamos and Sandia), three military R&D centers, three state universities, and numerous other technology based organizations, including a growing number of "high-tech" businesses and industries.

  5. Proceedings of the fourth workshop on grand unification

    Energy Technology Data Exchange (ETDEWEB)

    Weldon, H.A.; Langacker, P.; Steinhardt, P.J.

    1983-01-01

    This book compiles the papers presented at the fourth conference of grand unified theories of nuclear physics held in University of Pennsylvania April 1983. The topics covered were proton decay theory; angular distribution and flux of atmospheric neutrinos; atmospheric neutrinos and astrophysical neutrinos in proton decay experiments; review of future nucleon decay experiments; monopole experiments; searches for magnetic monopole; monopoles, gauge, fields and anomalies; darkmatter, galaxies and voids; adiabatic fluctuations; supersymmetry, supergravity, and Kaluza-Klein theories; superstring theory and superunification.

  6. Grande Ronde Basin Supplementation Program; Lostine River, 2000 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Onjukka, Sam T. (Oregon Department of Fish and Wildlife, Portland, OR); Harbeck, Jim (Nez Perce Tribe, Department of Fisheries Resource Management, Enterprise, OR)

    2003-03-01

    The Northwest Power Planning Council (NPPC) identified supplementation as a high priority to achieve its goal of increasing runs of anadromous fish in the Columbia Basin. Supplementation activities in the Lostine River and associated monitoring and evaluation conducted by the Nez Perce Tribe relate directly to the needs addressed in the Columbia River Basin Fish and Wildlife Program (NPPC 1994). Measure 7.4L.1 of the Program mandates that appropriate research accompany any proposed supplementation. In addition, measure 7.3B.2 of the Program stresses the need for evaluating supplementation projects to assess their ability to increase production. Finally, Section 7.4D.3 encourages the study of hatchery rearing and release strategies to improve survival and adaptation of cultured fish. In 1997, Oregon Department of Fisheries and Wildlife (ODFW) requested a modification of Permit 1011 to allow the take of adult spring chinook salmon. In 1998, the Nez Perce Tribe also requested a permit specific to activities on Lostine River. The permit was issued in 2000. A special condition in the permits required the development of a long term management plan for the spring chinook salmon of the Grande Ronde Basin. The Nez Perce Tribe, ODFW, and the Confederated Tribes of the Umatilla Indian Reservation (CTUIR) completed a formal long range plan entitled ''Grande Ronde Basin Endemic Spring Chinook Salmon Supplementation Program''. The program proposes to increase the survival of spring chinook salmon in the Grand Ronde Basin through hatchery intervention. Adult salmon from the Lostine River, Catherine Creek, and the Upper Grande Ronde River are used for a conventional supplementation program in the basin. The Nez Perce program currently operates under the ESA Section 10 Permit 1149.

  7. Grande Ronde Basin Supplementation Program; Lostine River, 2001 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Onjukka, Sam T. (Oregon Department of Fish and Wildlife, Portland, OR); Harbeck, Jim (Nez Perce Tribe, Department of Fisheries Resource Management, Enterprise, OR)

    2003-03-01

    The Northwest Power Planning Council (NPPC) identified supplementation as a high priority to achieve its goal of increasing runs of anadromous fish in the Columbia Basin. Supplementation activities in the Lostine River and associated monitoring and evaluation conducted by the Nez Perce Tribe relate directly to the needs addressed in the Columbia River Basin Fish and Wildlife Program (NPPC 1994). Measure 7.4L.1 of the Program mandates that appropriate research accompany any proposed supplementation. In addition, measure 7.3B.2 of the Program stresses the need for evaluating supplementation projects to assess their ability to increase production. Finally, Section 7.4D.3 encourages the study of hatchery rearing and release strategies to improve survival and adaptation of cultured fish. In 1997, Oregon Department of Fisheries and Wildlife (ODFW) requested a modification of Permit 1011 to allow the take of adult spring chinook salmon. In 1998, the Nez Perce Tribe also requested a permit specific to activities on Lostine River. The permit was issued in 2000. A special condition in the permits required the development of a long term management plan for the spring chinook salmon of the Grande Ronde Basin. The Nez Perce Tribe, ODFW, and the Confederated Tribes of the Umatilla Indian Reservation (CTUIR) completed a formal long range plan entitled ''Grande Ronde Basin Endemic Spring Chinook Salmon Supplementation Program''. The program proposes to increase the survival of spring chinook salmon in the Grand Ronde Basin through hatchery intervention. Adult salmon from the Lostine River, Catherine Creek, and the Upper Grande Ronde River are used for a conventional supplementation program in the basin. The Nez Perce program currently operates under the ESA Section 10 Permit 1149.

  8. Damming Grand Canyon: The 1923 USGS Colorado River Expedition

    OpenAIRE

    Boyer, Diane E.; Webb, Robert H.

    2007-01-01

    In 1923, America paid close attention, via special radio broadcasts, newspaper headlines, and cover stories in popular magazines, as a government party descended the Colorado to survey Grand Canyon. Fifty years after John Wesley Powell's journey, the canyon still had an aura of mystery and extreme danger. At one point, the party was thought lost in a flood. Something important besides adventure was going on. Led by Claude Birdseye and including colorful characters such as early river-runner E...

  9. Integrating electrodermal biofeedback into pharmacologic treatment of grand mal seizures

    OpenAIRE

    Tullio Michele Scrimali; Massimo Sciuto

    2015-01-01

    Electrodermal activity (EDA) and electrodermal biofeedback, when integrated with pharmacologic treatments, indicate promising methods for the treatment of grand mal seizures. They can be used to monitor patient arousal and help patients learn new strategies to better cope with stress and anxiety. Our proposed method can possibly reduce the number of crises for patients who are dependent on pharmacologic therapy and can improve their quality of life. This article describes the scientific backg...

  10. Differential compaction mechanism for earth fissures near Casa Grande, Arizona.

    Science.gov (United States)

    Jachens, R.C.; Holzer, T.L.

    1982-01-01

    Precise gravity measurements indicate that earth fissures or tension cracks caused by ground-water withdrawal within a 10km2 area SE of Casa Grande are associated with relief on the buried interface between the alluvial aquifer and underlying bedrock. These relations suggest that the fissures are forming in response to localized differential compaction caused by localized variations of aquifer-system thickness. -from Authors

  11. L'espace mondial des grandes manifestations sportives internationales

    Directory of Open Access Journals (Sweden)

    Daniel MATHIEU

    1989-06-01

    Full Text Available La carte des grandes manifestations sportives mondiales montre une forte concentration des épreuves dans un petit nombre de pays développés, en particulier l'Europe occidentale. L'examen des nations concernées par les tournois majeurs du tennis et par le cyclisme professionnel soulignent, avec les nuances propres à chacun des sports, l'étroitesse des espaces intéressés.

  12. China Overseas Plaza Mock-up Floor Grand Openning

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ Global Leasing launched on Full Scale Beijing, November 6, 2008- China Overseas Plaza, located at the heart of the Beijing CBD with Chang'an Avenue to the south and China World Trade Center PhasenⅢto the east, is constructed including two international Grade-A office towers with a commercial podium. The developer held a grand opening ceremony on the completed mock-up floor the sixth floor of the South Tower.

  13. Molecular epidemiology of HIV-1 in Rio Grande, RS, Brazil

    OpenAIRE

    Martínez Ana Maria Barral de; Barbosa Edel Figueirêdo; Ferreira Paulo César Pelegrino; Cardoso Fabiola Adriene; Silveira Jussara; Sassi Gabriela; Silva Cláudio Moss da; Mendonça-Signorini Vera; Antunes Carlos Maurício de Figueiredo

    2002-01-01

    We conducted a molecular epidemiological study to investigate HIV-1 strains in Rio Grande, southern Brazil, searching for an association with transmission mode and risk behavior. Patients (185) identified at an AIDS treatment reference Hospital, from 1994 to 1997, were included; from which 107 blood samples were obtained. Nested PCR was realized once for each sample; for amplified samples (69) HIV subtypes were classified using the heteroduplex mobility assay. Subtypes identified were B (75%)...

  14. Deciphering Solar Magnetic Activity: On Grand Minima in Solar Activity

    CERN Document Server

    McIntosh, Scott W

    2015-01-01

    The Sun provides the energy necessary to sustain our existence. While the Sun provides for us, it is also capable of taking away. The weather and climatic scales of solar evolution and the Sun-Earth connection are not well understood. There has been tremendous progress in the century since the discovery of solar magnetism - magnetism that ultimately drives the electromagnetic, particulate and eruptive forcing of our planetary system. There is contemporary evidence of a decrease in solar magnetism, perhaps even indicators of a significant downward trend, over recent decades. Are we entering a minimum in solar activity that is deeper and longer than a typical solar minimum, a "grand minimum"? How could we tell if we are? What is a grand minimum and how does the Sun recover? These are very pertinent questions for modern civilization. In this paper we present a hypothetical demonstration of entry and exit from grand minimum conditions based on a recent analysis of solar features over the past 20 years and their p...

  15. Integrating electrodermal biofeedback into pharmacologic treatment of grand mal seizures.

    Science.gov (United States)

    Scrimali, Tullio; Tomasello, Damiana; Sciuto, Massimo

    2015-01-01

    Electrodermal activity (EDA) and electrodermal biofeedback, when integrated with pharmacologic treatments, indicate promising methods for the treatment of grand mal seizures. They can be used to monitor patient arousal and help patients learn new strategies to better cope with stress and anxiety. Our proposed method can possibly reduce the number of crises for patients who are dependent on pharmacologic therapy and can improve their quality of life. This article describes the scientific background of electrodermal monitoring and electrodermal biofeedback for patients affected by grand mal seizures. In this study, we have reported a clinical case study. The patient was treated for 2 years with electrodermal biofeedback to augment pharmacologic treatments. The trial has been designed in accordance with "n = 1 case study research". Our results have shown that our methods could achieve a significant reduction in grand mal seizures and sympathetic arousal when applied. The patient under consideration was also relaxed and exhibited greater competency to cope with stress. Additionally, the patient's sense of mastery and self-efficacy was enhanced. PMID:26029078

  16. High resolution beam line for the Grand Raiden spectrometer

    International Nuclear Information System (INIS)

    We have designed and constructed a new beam line which can accomplish both lateral and angular dispersion matching with the Grand Raiden spectrometer. In dispersive mode, lateral and angular dispersions of the beam line are b16=37.1 m and b26=-20.0 rad, respectively, to satisfy matching conditions for Grand Raiden. In achromatic mode, the beam line satisfies the double achromatic condition of b16=b26=0. The magnifications of the beam line are (Mx,My)=(-0.98,0.89) and (-1.00,-0.99) for dispersive and achromatic modes, respectively. In the commissioning experiments, we have succeeded to separate the first excited 2+ state of 168Er with Ex=79.8 keV clearly from the ground state in the (p,p') reaction. We achieved energy resolutions of ΔE=13.0±0.3 and 16.7±0.3 keV in full width at half-maximum for 295 and 392 MeV protons, respectively. These energy resolutions agree with the resolving power of Grand Raiden for an object size of about 1 mm

  17. Lower Grande Ronde smolt trap monitoring. Annual report 1996

    International Nuclear Information System (INIS)

    The authors sampled downstream migrating salmonids at Boggan's Oasis in the Grande Ronde River with a screw trap during 1995 and a scoop trap during 1996. Sampling began in March and terminated early in June. Wild spring chinook and wild/hatchery steelhead were collected and marked to assess migration patterns and timing. Fish were marked with tags in order to obtain downstream migration data with minimal fish handling. Observations were recorded when a fish swam through an interrogation monitor at hydroelectric facilities downstream. The second year for monitoring smolts leaving the Grande Ronde River was completed in 1995. The authors continued to pursue moving to a permanent location downstream for 1997 because of the limitations for trapping smolts at Boggan's Oasis. This involved reconnaissance surveys of several potential sites near the mouth of the river from 1994--1996. During February of 1996, a water velocity and bottom topography assessment was completed. Results of the assessment were used for siting the anchoring tower structure upstream approximately 1.2 miles from the mouth of the Grande Ronde River

  18. Masses and Mixings in a Grand Unified Toy Model

    CERN Document Server

    McKeen, D; Thalapillil, A M; Keen, David Mc; Rosner, Jonathan L.; Thalapillil, Arun M.

    2007-01-01

    The generation of the fermion mass hierarchy in the standard model of particle physics is a long-standing puzzle. The recent discoveries from neutrino physics suggests that the mixing in the lepton sector is large compared to the quark mixings. To understand this asymmetry between the quark and lepton mixings is an important aim for particle physics. In this regard, two promising approaches from the theoretical side are grand unified theories and family symmetries. In this note we try to understand certain general features of grand unified theories with Abelian family symmetries by taking the simplest SU(5) grand unified theory as a prototype. We construct an SU(5) toy model with $U(1)_F \\otimes Z'_2\\otimes Z''_2 \\otimes Z'''_2$ family symmetry that, in a natural way, duplicates the observed mass hierarchy and mixing matrices to lowest approximation. The system for generating the mass hierarchy is through a Froggatt-Nielsen type mechanism. One idea that we use in the model is that the quark and charged lepton...

  19. Integration of Complex Models Into a System Dynamics Based Basin Scale Planning Model for the Upper Rio Grande

    Science.gov (United States)

    Roach, J.; Tidwell, V.; Lansey, K.

    2004-12-01

    As the finite, and often over-allocated water resources of the western United States are challenged by a myriad of growing demands, computer based simulations can be a powerful tool for evaluation of potential water use scenarios for hydrologic decision making and water policy analysis. To maximize their usefulness for policy analysis, such simulations should accurately represent the physical system as well as its interconnectedness to the socio-economic systems relevant to water planning without losing user accessibility or run speed. One solution to these constraints is system dynamics (SD) modeling at a relatively coarse spatial and temporal resolution. The challenge of this approach is in maintaining sufficient physical accuracy despite coarse resolution and SD's simple modeling framework. In this paper, the development of a reach-based monthly time-step system dynamics model of the upper Rio Grande River (from the headwaters in Colorado to Elephant Butte Reservoir in New Mexico) is discussed. Within this SD model, temporally and spatially coarse physical and operational relationships are abstracted from a variety of existing models with higher resolutions, including an operations model (Upper Rio Grande Water Operations Model (URGWOM)), a land surface rainfall-runoff model, an evapotranspiration model, and two groundwater models. Abstraction and calibration methods and implications of information loss associated with this scaling are considered.

  20. Environmental assessment of facility operations at the U.S. Department of Energy Grand Junction Projects Office, Grand Junction, Colorado

    International Nuclear Information System (INIS)

    The US Department of Energy (DOE) has prepared a sitewide environmental assessment (EA) of the proposed action to continue and expand present-day activities on the DOE Grand Junction Projects Office (GJPO) facility in Grand Junction, Colorado. Because DOE-GJPO regularly proposes and conducts many different on-site activities, DOE decided to evaluate these activities in one sitewide EA rather than in multiple, activity-specific documents. On the basis of the information and analyses presented in the EA, DOE has determined that the proposed action does not constitute a major Federal action significantly affecting the quality of the human environment, as defined by the National Environmental Policy Act (NEPA) of 1969. Therefore, preparation of an environmental impact statement is not required for facility operations, and DOE is issuing this Finding of No Significant Impact (FONSI)

  1. Environmental assessment of facility operations at the U.S. Department of Energy Grand Junction Projects Office, Grand Junction, Colorado

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-06-01

    The US Department of Energy (DOE) has prepared a sitewide environmental assessment (EA) of the proposed action to continue and expand present-day activities on the DOE Grand Junction Projects Office (GJPO) facility in Grand Junction, Colorado. Because DOE-GJPO regularly proposes and conducts many different on-site activities, DOE decided to evaluate these activities in one sitewide EA rather than in multiple, activity-specific documents. On the basis of the information and analyses presented in the EA, DOE has determined that the proposed action does not constitute a major Federal action significantly affecting the quality of the human environment, as defined by the National Environmental Policy Act (NEPA) of 1969. Therefore, preparation of an environmental impact statement is not required for facility operations, and DOE is issuing this Finding of No Significant Impact (FONSI).

  2. International Collaboration: Promises and Challenges

    Directory of Open Access Journals (Sweden)

    R. Jay Widmer

    2015-04-01

    Full Text Available Rambam Maimonides Medical Journal 2015 April; 6(2: e0012. ISSN: 2076-9172 Published online 2015 April 29. Special Issue on the Rambam-Mayo Collaboration Guest Editor: John H. Davidson, M.D., M.A.H.L. doi: 10.5041/RMMJ.10196. International Collaboration: Promises and Challenges R. Jay Widmer, M.D., Ph.D.,1 Jocelyn M. Widmer, Ph.D., M.P.H.,2 and Amir Lerman, M.D.1* 1Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic and College of Medicine, Rochester, MN, USA; 2Department of Urban and Regional Planning, College of Design, Construction and Planning, University of Florida, Gainesville, FL, USA Conflict of interest: No potential conflict of interest relevant to this article was reported. * To whom correspondence should be addressed. E-mail: lerman.amir@mayo.edu Copyright: © 2015 Widmer et al. This is an open-access article. All its content, except where otherwise noted, is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract We currently face a myriad of grand global challenges in fields such as poverty, the environment, education, science, and medicine. However, our current means of dealing with such challenges has fallen short, and ingenious solutions are required to overcome the inherent resistance to progress toward ameliorating such difficulties. Here, we highlight the promises and challenges of international collaboration in achieving success toward these trials. We note prior successes in fields such as education, medicine, science, and environmental issues made to date, yet at the same time we do note deficiencies and shortcomings in these efforts. Hence, the notion of international collaboration should be strengthened and encouraged by governments, non-profit organizations, and others moving forward using creative

  3. Microbial contamination and chemical toxicity of the Rio Grande

    Science.gov (United States)

    Mendoza, Jose; Botsford, James; Hernandez, Jose; Montoya, Anna; Saenz, Roswitha; Valles, Adrian; Vazquez, Alejandro; Alvarez, Maria

    2004-01-01

    Background The Rio Grande River is the natural boundary between U.S. and Mexico from El Paso, TX to Brownsville, TX. and is one of the major water resources of the area. Agriculture, farming, maquiladora industry, domestic activities, as well as differences in disposal regulations and enforcement increase the contamination potential of water supplies along the border region. Therefore, continuous and accurate assessment of the quality of water supplies is of paramount importance. The objectives of this study were to monitor water quality of the Rio Grande and to determine if any correlations exist between fecal coliforms, E. coli, chemical toxicity as determined by Botsford's assay, H. pylori presence, and environmental parameters. Seven sites along a 112-Km segment of the Rio Grande from Sunland Park, NM to Fort Hancock, TX were sampled on a monthly basis between January 2000 and December 2002. Results The results showed great variability in the number of fecal coliforms, and E. coli on a month-to-month basis. Fecal coliforms ranged between 0–106 CFU/100 ml while E. coli ranged between 6 to > 2419 MPN. H. pylori showed positive detection for all the sites at different times. Toxicity ranged between 0 to 94% of inhibition capacity (IC). Since values above 50% are considered to be toxic, most of the sites displayed significant chemical toxicity at different times of the year. No significant correlations were observed between microbial indicators and chemical toxicity. Conclusion The results of the present study indicate that the 112-Km segment of the Rio Grande river from Sunland Park, NM to Fort Hancock, TX exceeds the standards for contact recreation water on a continuous basis. In addition, the presence of chemical toxicity in most sites along the 112-Km segment indicates that water quality is an area of concern for the bi-national region. The presence of H. pylori adds to the potential health hazards of the Rio Grande. Since no significant correlation was

  4. Molecular epidemiology of HIV-1 in Rio Grande, RS, Brazil Epidemiologia molecular do HIV-1 em Rio Grande, RS, Brasil

    OpenAIRE

    Ana Maria Barral de Martínez; Edel Figueirêdo Barbosa; Paulo César Pelegrino Ferreira; Fabiola Adriene Cardoso; Jussara Silveira; Gabriela Sassi; Cláudio Moss da Silva; Vera Mendonça-Signorini; Carlos Maurício de Figueiredo Antunes

    2002-01-01

    We conducted a molecular epidemiological study to investigate HIV-1 strains in Rio Grande, southern Brazil, searching for an association with transmission mode and risk behavior. Patients (185) identified at an AIDS treatment reference Hospital, from 1994 to 1997, were included; from which 107 blood samples were obtained. Nested PCR was realized once for each sample; for amplified samples (69) HIV subtypes were classified using the heteroduplex mobility assay. Subtypes identified were B (75%)...

  5. Pathogenic Landscape of Transboundary Zoonotic Diseases in the Mexico-US Border Along the Rio Grande.

    Science.gov (United States)

    Esteve-Gassent, Maria Dolores; Pérez de León, Adalberto A; Romero-Salas, Dora; Feria-Arroyo, Teresa P; Patino, Ramiro; Castro-Arellano, Ivan; Gordillo-Pérez, Guadalupe; Auclair, Allan; Goolsby, John; Rodriguez-Vivas, Roger Ivan; Estrada-Franco, Jose Guillermo

    2014-01-01

    Transboundary zoonotic diseases, several of which are vector borne, can maintain a dynamic focus and have pathogens circulating in geographic regions encircling multiple geopolitical boundaries. Global change is intensifying transboundary problems, including the spatial variation of the risk and incidence of zoonotic diseases. The complexity of these challenges can be greater in areas where rivers delineate international boundaries and encompass transitions between ecozones. The Rio Grande serves as a natural border between the US State of Texas and the Mexican States of Chihuahua, Coahuila, Nuevo León, and Tamaulipas. Not only do millions of people live in this transboundary region, but also a substantial amount of goods and people pass through it everyday. Moreover, it occurs over a region that functions as a corridor for animal migrations, and thus links the Neotropic and Nearctic biogeographic zones, with the latter being a known foci of zoonotic diseases. However, the pathogenic landscape of important zoonotic diseases in the south Texas-Mexico transboundary region remains to be fully understood. An international perspective on the interplay between disease systems, ecosystem processes, land use, and human behaviors is applied here to analyze landscape and spatial features of Venezuelan equine encephalitis, Hantavirus disease, Lyme Borreliosis, Leptospirosis, Bartonellosis, Chagas disease, human Babesiosis, and Leishmaniasis. Surveillance systems following the One Health approach with a regional perspective will help identifying opportunities to mitigate the health burden of those diseases on human and animal populations. It is proposed that the Mexico-US border along the Rio Grande region be viewed as a continuum landscape where zoonotic pathogens circulate regardless of national borders. PMID:25453027

  6. Pathogenic Landscape of Transboundary Zoonotic Diseases in the Mexico–US Border Along the Rio Grande

    Science.gov (United States)

    Esteve-Gassent, Maria Dolores; Pérez de León, Adalberto A.; Romero-Salas, Dora; Feria-Arroyo, Teresa P.; Patino, Ramiro; Castro-Arellano, Ivan; Gordillo-Pérez, Guadalupe; Auclair, Allan; Goolsby, John; Rodriguez-Vivas, Roger Ivan; Estrada-Franco, Jose Guillermo

    2014-01-01

    Transboundary zoonotic diseases, several of which are vector borne, can maintain a dynamic focus and have pathogens circulating in geographic regions encircling multiple geopolitical boundaries. Global change is intensifying transboundary problems, including the spatial variation of the risk and incidence of zoonotic diseases. The complexity of these challenges can be greater in areas where rivers delineate international boundaries and encompass transitions between ecozones. The Rio Grande serves as a natural border between the US State of Texas and the Mexican States of Chihuahua, Coahuila, Nuevo León, and Tamaulipas. Not only do millions of people live in this transboundary region, but also a substantial amount of goods and people pass through it everyday. Moreover, it occurs over a region that functions as a corridor for animal migrations, and thus links the Neotropic and Nearctic biogeographic zones, with the latter being a known foci of zoonotic diseases. However, the pathogenic landscape of important zoonotic diseases in the south Texas–Mexico transboundary region remains to be fully understood. An international perspective on the interplay between disease systems, ecosystem processes, land use, and human behaviors is applied here to analyze landscape and spatial features of Venezuelan equine encephalitis, Hantavirus disease, Lyme Borreliosis, Leptospirosis, Bartonellosis, Chagas disease, human Babesiosis, and Leishmaniasis. Surveillance systems following the One Health approach with a regional perspective will help identifying opportunities to mitigate the health burden of those diseases on human and animal populations. It is proposed that the Mexico–US border along the Rio Grande region be viewed as a continuum landscape where zoonotic pathogens circulate regardless of national borders. PMID:25453027

  7. Pathogenic landscape of transboundary zoonotic diseases in the Mexico-US border along the Rio Grande

    Directory of Open Access Journals (Sweden)

    Maria Dolores Esteve-Gasent

    2014-11-01

    Full Text Available Transboundary zoonotic diseases, several of which are vector borne, can maintain a dynamic focus, and have pathogens circulating in geographic regions encircling multiple geopolitical boundaries. Global change is intensifying transboundary problems including the spatial variation of the risk and incidence of zoonotic diseases. The complexity of these challenges can be greater in areas where rivers delineate international boundaries and encompass transitions between ecozones. The Rio Grande serves as a natural border between the US State of Texas and the Mexican States of Chihuahua, Coahuila, Nuevo León, and Tamaulipas. Not only millions of people live in this transboundary region but also a substantial movement of goods and people pass through it everyday. Moreover, it occurs over a region that functions as a corridor for animal migrations, and thus links the Neotropic and Nearctic biogeographic zones, with the latter being a known foci of zoonotic diseases. However, the pathogenic landscape of important zoonotic diseases in the south Texas-Mexico transboundary region remains to be fully understood. An international perspective on the interplay between disease systems, ecosystem processes, land use, and human behaviors is applied here to analyze landscape and spatial features of Venezuelan equine encephalitis, Hantavirus disease, Lyme Borreliosis, Leptospirosis, Bartonellosis, Chagas disease, human Babesiosis, and Leishmaniasis. Surveillance systems following the One Health approach with a regional perspective will help identifying opportunities to mitigate the health burden of those diseases on human and animal populations. It is proposed that the Mexico-US border, along the Rio Grande region be viewed as a continuum landscape where zoonotic pathogens circulate regardless of national borders.

  8. LabTrove: A Lightweight, Web Based, Laboratory “Blog” as a Route towards a Marked Up Record of Work in a Bioscience Research Laboratory

    OpenAIRE

    Milsted, Andrew J.; Hale, Jennifer R.; Frey, Jeremy G.; Cameron Neylon

    2013-01-01

    Background The electronic laboratory notebook (ELN) has the potential to replace the paper notebook with a marked-up digital record that can be searched and shared. However, it is a challenge to achieve these benefits without losing the usability and flexibility of traditional paper notebooks. We investigate a blog-based platform that addresses the issues associated with the development of a flexible system for recording scientific research. Methodology/Principal Findings We chose...

  9. Micetomas actinomicóticos no Rio Grande do Sul: relato de quatro casos Actinomycotic mycetomas in Rio Grande do Sul: report of 4 cases

    Directory of Open Access Journals (Sweden)

    Alberto T. Londero

    1986-03-01

    Full Text Available São relatados quatro casos de micetoma causados por Nocardia brasiliensis, ocorridos no Rio Grande do Sul. É revista a literatura rio-grandense-do-sul.Four cases of mycetoma caused by N. brasiliensis, occurring in Rio Grande do Sul (Brazil, are reported.

  10. Novel opportunities and challenges offered by nanobiomaterials in tissue engineering

    Directory of Open Access Journals (Sweden)

    Fabrizio Gelain

    2008-08-01

    Full Text Available Fabrizio GelainBioscience and Biotechnology Department, University of Milan-Bicocca, Milan, ItalyAbstract: Over the last decades, tissue engineering has demonstrated an unquestionable potential to regenerate damaged tissues and organs. Some tissue-engineered solutions recently entered the clinics (eg, artificial bladder, corneal epithelium, engineered skin, but most of the pathologies of interest are still far from being solved. The advent of stem cells opened the door to large-scale production of “raw living matter” for cell replacement and boosted the overall sector in the last decade. Still reliable synthetic scaffolds fairly resembling the nanostructure of extracellular matrices, showing mechanical properties comparable to those of the tissues to be regenerated and capable of being modularly functionalized with biological active motifs, became feasible only in the last years thanks to newly introduced nanotechnology techniques of material design, synthesis, and characterization. Nanostructured synthetic matrices look to be the next generation scaffolds, opening new powerful pathways for tissue regeneration and introducing new challenges at the same time. We here present a detailed overview of the advantages, applications, and limitations of nanostructured matrices with a focus on both electrospun and self-assembling scaffolds.Keywords: self-assembling peptide, electrospinning, tissue engineering, functionalization

  11. National Drug IQ Challenge

    Science.gov (United States)

    ... Drug & Alcohol IQ Challenge 2016 National Drug & Alcohol IQ Challenge Get Started! Correct/Total Questions: Score: Other ... accessible version of the 2016 National Drug & Alcohol IQ Challenge , [PDF, 637KB]. Download an accessible version of ...

  12. Grandes sistemas fluviais tropicais: uma visão geral

    Directory of Open Access Journals (Sweden)

    Rajiv Sinha

    2010-04-01

    Full Text Available Muitos dos grandes rios e dos leques aluviais existentes estão situados em áreas tropicais e constituem os maiores sistemas de estoque e transferência de sedimentos e nutrientes para o oceano. O presente trabalho visa a apresentação e análise geral dos grandes sistemas fluviais e leques aluviais (área da bacia entre 104 e 6 x 106 km de regiões tropicais com precipitação acima de 700 mm anuais. Os grandes sistemas fluviais tropicais foram aqui classificados de acordo com o arcabouço geológico-geomorfológio de suas bacias em: a Cinturões orogenênicos de montanha, b Platô/plataforma basáltico-sedimentar, c Áreas cratônicas, d Planícies em áreas de bacias sedimentares, e e Áreas mistas. De modo geral, os rios analisados apresentam um pico de descarga bastante definido e variável durante a estação chuvosa e um período de baixa vazão na estação seca. Os dados dos rios sul-americanos e asiáticos de áreas continentais e orogênicas agruparam-se quando lançados num diagrama do suprimento de sedimentos versus descarga média anual, e apresentaram valores mais elevados que aqueles asiáticos insulares. Já rios de áreas de plataforma ou cratônicas, tanto em área de savana como nos trópicos úmidos, caracterizaram-se por terem baixo transporte de sedimento. Especialmente nas grandes bacias, os rios apresentam toda a gama de formas de canal, inviabilizando a classificação tradicional de canal meandrante, reto e entrelaçado, sendo nesse caso mais sugestiva a aplicação da terminologia de sistema uni ou multi-canal ou de complexo anastomosado.É também discutido, brevemente, o atual estado do conhecimento dos sistemas fluviais tropicais e seu potencial na aplicação na interpretação de antigas seqüências e na modelagem de fácies sedimentar. Os principais impactos ambientais a que os grandes sistemas fluviais tropicais estão submetidos incluem as mudanças no uso agrosilpastoril das terras, mineração, barragens

  13. Los primeros contactos de los europeos con las grandes altitudes

    OpenAIRE

    Mas Galvañ, Cayetano

    2011-01-01

    Uno de los aspectos menos conocidos en el proceso de la expansión mundial europea es el del contacto con las altas cadenas montañosas americanas y asiáticas (Andes e Himalaya), y en especial la penetración en las grandes altitudes, superiores a 4.000 metros. En este trabajo se analizan las principales fuentes relacionadas con la presencia de europeos por encima de esas cotas, en el doble terreno de la percepción subjetiva y los episodios de mal agudo de montaña, y en el del avance en la medic...

  14. Búsquedas en grandes volúmenes de datos

    OpenAIRE

    Britos, Luis; Di Gennaro, María E.; Gil Costa, Graciela Verónica; Kasián, Fernando; Lobos, Jair; Ludueña, Verónica; Molina, Romina; Printista, Alicia Marcela; Reyes, Nora Susana; Roggero, Patricia; Trabes, Guillermo

    2016-01-01

    En la actualidad los sistemas de información demandan no sólo poder realizar búsquedas eficientes sobre distintos tipos de datos, tales como texto libre, audio, video, secuencias de ADN, etc., sino también poder manejar grandes volúmenes de estos datos. Dada una consulta, el objetivo de un sistema de recuperación de información es obtener lo que podría ser útil o relevante para el usuario, usando una estructura de almacenamiento especialmente diseñada para responderla eficientemente. Nuest...

  15. Ethical Grand Rounds: Teaching Ethics at the Point of Care.

    Science.gov (United States)

    Airth-Kindree, Norah M M; Kirkhorn, Lee-Ellen C

    2016-01-01

    We offer an educational innovation called Ethical Grand Rounds (EGR) as a teaching strategy to enhance ethical decision-making. Nursing students participate in EGR-flexible ethical laboratories, where they take stands on ethical dilemmas, arguing for--or against--an ethical principle. This process provides the opportunity to move past normative ethics, that is, an ideal ethical stance in accord with ethical conduct codes, to applied ethics, what professional nurses would do in actual clinical practice, given the constraints that exist in contemporary care settings. EGR serves as a vehicle to translate "what ought to be" into "what is." PMID:27164779

  16. La Grande Guerra e la cultura politica britannica

    OpenAIRE

    Palazzolo, Claudio

    2014-01-01

    La conferenza illustra la reazione della cultura politica britannica nei confronti della Grande Guerra usando come campione rappresentativo il Leonard Hobhouse di "The Metaphysical Theory of the State" nel suo confronto con il neo-hegelismo di T.H. Green, da un lato, e di Bernard Bosanquet, dall'altro. Il contesto neo-idealistico di questo confronto mostra che, pur in uno spettro di posizioni molto ampio, la cultura britannica si va orientando verso un nuovo apprezzamento dell'idea di stato.

  17. Grande Ronde Basin Fish Habitat Enhancement Project : 2000 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    McGowan, Vance R.; Powell, Russ M.; Stennfeld, Scott P.

    2001-04-01

    On July 1, 1984 the Bonneville Power Administration and the Oregon Department of Fish and Wildlife entered into an agreement to initiate fish habitat enhancement work in the Joseph Creek subbasin of the Grande Ronde River Basin in northeast Oregon. In July of 1985 the Upper and Middle Grande Ronde River, and Catherine Creek subbasins were included in the intergovernmental contract, and on March 1, 1996 the Wallowa River subbasin was added. The primary goal of ''The Grande Ronde Basin Fish Habitat Enhancement Project'' is to access, create, improve, protect, and restore riparian and instream habitat for anadromous salmonids, thereby maximizing opportunities for natural fish production within the basin. This project provided for implementation of Program Measure 703 (C)(1), Action Item 4.2 of the Northwest Power Planning Council's Columbia River Basin Fish and Wildlife Program (NPPC, 1987), and continues to be implemented as offsite mitigation for mainstem fishery losses caused by the Columbia River hydro-electric system. All work conducted by the Oregon Department of Fish and Wildlife is on private lands and therefore requires that considerable time be spent developing rapport with landowners to gain acceptance of, and continued cooperation with this program throughout 10-15 year lease periods. This project calls for passive regeneration of habitat, using riparian enclosure fencing as the primary method to restore degraded streams to a normative condition. Active remediation techniques using plantings, off-site water developments, site-specific instream structures, or whole channel alterations are also utilized where applicable. Individual projects contribute to and complement ecosystem and basin-wide watershed restoration efforts that are underway by state, federal, and tribal agencies, and local watershed councils. Work undertaken during 2000 included: (1) Implementing 2 new projects in the Grande Ronde drainage, and retrofitting one old

  18. Softening the supersymmetric flavor problem in orbifold grand unified theories

    International Nuclear Information System (INIS)

    The infrared attractive force of the bulk gauge interactions is applied to soften the supersymmetric flavor problem in the orbifold SU(5) grand unified theory of Kawamura. Then this force aligns in the infrared regime the soft supersymmetry breaking terms out of their anarchical disorder at a fundamental scale, in such a way that flavor-changing neutral currents as well as dangerous CP-violating phases are suppressed at low energies. It is found that this dynamical alignment is sufficiently good compared with the current experimental bounds, as long as the diagonalization matrices of the Yukawa couplings are CKM-like

  19. Reprodução de peixes (Osteichthyes em afluentes do reservatório de Volta Grande, Rio Grande, Sudeste do Brasil Fishes reproduction in the Volta Grande dam tributaries, Grande River, Southeastern Brazil

    Directory of Open Access Journals (Sweden)

    Francisco Manoel de Souza Braga

    Full Text Available The most abundant species caught in the tributaries of the Volta Grande dam, Buriti, Divisa and Água Comprida streams were Plagioscion squamosissimus (Heckel, 1840, Pimelodus maculatus Lacépède 1803, Myleus tiete (Eigenmann & Norris, 1900, Astyanax bimaculatus (Linnaeus, 1758 and A. fasciatus (Cuvier, 1819. Plagioscion squamosissimus and Pimelodus maculatus do not have reproduction activity in the area, they just use the creeks to food and growth. Myleus tiete and Astyanax bimaculatus use the area to reproduction whereas A. fasciatus uses it to reproduction, food and growth.

  20. Seesaw Scale in the Minimal Renormalizable SO(10) Grand Unification

    OpenAIRE

    Bertolini, Stefano; Di Luzio, Luca; Malinsky, Michal

    2012-01-01

    Simple SO(10) Higgs models with the adjoint representation triggering the grand-unified symmetry breaking, discarded a long ago due to inherent tree-level tachyonic instabilities in the physically interesting scenarios, have been recently brought back to life by quantum effects. In this work we focus on the variant with 45_H+126_H in the Higgs sector and show that there are several regions in the parameter space of this model that can support stable unifying configurations with the B-L breaki...

  1. Wedge Structures in Southernmost Argentina (Rio Grande, Tierra del Fuego)

    OpenAIRE

    Pérez Alberti, Augusto; Coronato, Andrea; Costa-Casais, Manuela; Valcarcel-Díaz, Marcos

    2008-01-01

    [EN] Wedge-like structures occur in raised beach gravels near Rio Grande, eastern Tierra Del Fuego (latitude 53°50′S; longitude 67°5′W). They vary in dimension, being approximately 1.0–1.5 m deep and 0.3–0.8 m in apparent width. Some are closely spaced, while others are as much as 5.0–8.0 m apart. The infill is predominantly fine and coarse sand, together with silt, all of local provenance. There is little evidence of secondary infill. It is unclear whether these structures are soil wedges, s...

  2. Grande Ronde Endemic Spring Chinook Project - ODFW, 2008 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Patterson, Scott

    2009-04-10

    Core activities of the Grande Ronde Endemic Spring Chinook Supplementation Program (GRESCSP) are funded through the authority of the Lower Snake River Fish and Wildlife Compensation Plan (LSRCP). The LSRCP program was approved by the Water Resources Development Act of 1976, PL 94-587, Section 102, 94th Congress substantially in accordance with the Special Report, LSRCP, June 1975 on file with the Chief of Engineers. The LSRCP was prepared and submitted in compliance with the Fish and Wildlife Coordination Act of 1958, PL 85-624, 85th Congress, August 12, 1958 to mitigate for the losses of fish and wildlife caused by the construction of dams on lower Snake River. The GRESCSP is an artificial propagation program that was initiated by Bonneville Power Administrations Fish and Wildlife program in the mid 1990's. The intent of this program was to change the mitigation aspect of the LSRCP program (harvest mitigation) to an integrated supplementation program; inasmuch as, hatchery produced fish could be experimentally used as a recovery tool and fish surplus to mitigation would be available for in-place and in-kind harvest. Fish production is still authorized by the LSRCP with the original mitigation return goal of 5,860 adult spring Chinook to the project area. The GRESCSP was developed with two primary components: (1) conventional broodstock (projects 199800702; 199800703; 199800704) and (2) captive brood (projects 199801001; 199801006). The GRESCSP relies on cooperative M&E efforts from the LSRCP including setting aside the Wenaha and Minam tributaries as natural production reserves components used for reference streams. The GRESCSP, coordinated with federal and tribal partners, identifies production levels for both propagation components and weir management strategies for each of the three supplemented tributary areas within the Grande Ronde Sub-basin. The three supplemented areas are Catherine Creek, Lostine River, and upper Grande Ronde River. Lookingglass

  3. Stability of mass hierarchy in locally supersymmetric grand unification

    International Nuclear Information System (INIS)

    Some locally supersymmetric SU(5) grand unified models with a sliding singlet and two pairs of 5sub(tilde) and 5sub(tilde)* Higgs multiplets are considered from the viewpoint of universal baryon asymmetry and the one-loop stability of mass hierarchy. A new mechanism based on ''sliding singlet reflection symmetry'' to avoid the problem of the mass hierarchical stability is proposed. The stability is shown up to two-loop levels for some models. All order stability is also discussed. (author)

  4. Em cena, o grande teatro do mundo de Jorge Lima.

    OpenAIRE

    Quadros, Deisily de

    2011-01-01

    Abstract: “O Grande Circo Místico”, is a poem written by Jorge de Lima which is in A túnica inconsútil, a book from the top of spiritualist phase of the poet. Two adaptations for ballet were done based on this poem. They were named as the poem and presented in 1983 and 2002. Both of them had a good reception in the society and by the criticalsand have been not only in all the country but also in Portugal. This search intends to crify how the poem interpretations occured analysing the way that...

  5. TeV colored Higgsinos in alternative grand unified theories

    International Nuclear Information System (INIS)

    Recently, a type of grand unified theory model with an extra dimension in AdS space has successfully solved the doublet-triplet problem, maintaining proton stability, and allowing colored Higgs bosons and colored Higgsinos in the TeV mass region. We study the hadronic production and detection of these TeV colored Higgsinos and Higgs bosons. If the colored Higgsino is lighter than the colored Higgs boson, the colored Higgs boson will decay into a colored Higgsino and a gluino or a gravitino, and vice versa. The signatures would be stable massive charged particles with jets or missing energies

  6. Google Science Fair 2012 : Grand Prize Winner Brittany Wenger

    CERN Multimedia

    Maximilien Brice

    2012-01-01

    17-18 age category AND Grand Prize Winner: Brittany Wenger (USA)—“Global Neural Network Cloud Service for Breast Cancer.” Brittany’s project harnesses the power of the cloud to help doctors accurately diagnose breast cancer. Brittany built an application that compares individual test results to an extensive dataset stored in the cloud, allowing doctors to assess tumors using a minimally-invasive procedure. Brittany Michelle Wenger, and her mother, passed through the CERN Control Centre accompanied by Mike Lamont, CERN Beams Department, Operation Group Leader.

  7. Bioética, violência e desigualdade: as biociências e a constituição do biopoder Bioethics, violence and inequality: the biosciences and the conquest of biopower

    Directory of Open Access Journals (Sweden)

    Hélder Boska de Moraes Sarmento

    2008-12-01

    Full Text Available A sociedade contemporânea está atravessada por contradições e paradoxos, dentre os quais vale destacar a relação entre a alta tecnologia e, a pior situação humana, a miséria. Resultado das escolhas éticas e políticas desta era tecnológica, vive-se em situações de fronteira, nas quais as biociências desempenham papel central, tanto no volume de conhecimentos gerados, como na utilização de seus resultados, que, sem controle social, ampliam desigualdades. O objetivo deste artigo é demonstrar o quanto as biociências articulam-se com o desenvolvimento científico dos países inovadores de tecnologia, criando uma nova relação de poder, violento e desigual para os que apenas a consomem, denominado de biopoder. Daí a necessidade de uma bioética crítica capaz de empreender reflexões sobre os procedimentos técnicos, os fundamentos da atividade científica, sua aplicabilidade e relação com o mercado, oportunizando uma 'ponte' na tomada de decisões para que a própria ciência não se torne um obstáculo à democracia.Contemporary society is rife with contradictions and paradoxes, among which stand out the relationship between high technology and the worst human situation, poverty. The result of ethical and political choices of this technological era, we experience frontier situations, in which the biosciences play a central role, both in the volume of knowledge generated, as well as in the use of their results which, without social control, broaden inequalities. The objective of this article is to demonstrate the degree to which the biosciences are articulated with the scientific development of the countries that innovate technologies, creating a new relationship of power, which is violent and unequal for those who only consume, denominated biopower. This creates a need for a critical bioethics that is capable of reflecting on the technical procedures, the bases of scientific activity and their applicability and relation with

  8. Statistical thermodynamics in relativistic particle and ion physics: Canonical or grand canonical

    International Nuclear Information System (INIS)

    We consider relativistic statistical thermodynamics of an ideal Boltzmann gas consisting of the particles K, Λ, A, Σ and their antiparticles. Baryon number (B) and strangeness (S) are conserved. While any relativistic gas is necessarily grand canonical with respect to particle numbers, conservation laws can be treated canonically or grand canonically. We construct the partition function for canonical BxS conservation and compare it with the grand canonical one. It is found that the grand canonical partition function is equivalent to a large B approximation of the canonical one. The relative difference between canonical and grand canonical quantities seems to decrease like const/B (two numerical examples) and from this a simple thumb rule for computing canonical quantities from grand canonical ones is guessed. For precise calculations, an integral representation is given. (orig.)

  9. Vigilando la Calidad del Agua de los Grandes Rios de la Nacion: El Programa NASQAN del Rio Grande (Rio Bravo del Norte)

    Science.gov (United States)

    Lurry, Dee L.; Reutter, David C.; Wells, Frank C.; Rivera, M.C., (translator); Munoz, A.

    1998-01-01

    La Oficina del Estudio Geologico de los Estados Unidos (U.S. Geological Survey, 0 USGS) ha monitoreado la calidad del agua de la cuenca del Rio Grande (Rio Bravo del Norte) desde 1995 como parte de la rediseiiada Red Nacional para Contabilizar la Calidad del Agua de los Rios (National Stream Quality Accounting Network, o NASOAN) (Hooper and others, 1997). EI programa NASOAN fue diseiiado para caracterizar las concentraciones y el transporte de sedimento y constituyentes quimicos seleccionados, encontrados en los grandes rios de los Estados Unidos - incluyendo el Misisipi, el Colorado y el Columbia, ademas del Rio Grande. En estas cuatro cuencas, el USGS opera actualmente (1998) una red de 40 puntos de muestreo pertenecientes a NASOAN, con un enfasis en cuantificar el flujo en masa (la cantidad de material que pasa por la estacion, expresado en toneladas por dial para cada constituyente. Aplicacando un enfoque consistente, basado en la cuantificacion de flujos en la cuenca del Rio Grande, el programa NASOAN esta generando la informacion necesaria para identificar fuentes regionales de diversos contaminantes, incluyendo sustancias qui micas agricolas y trazas elementos en la cuenca. EI efecto de las grandes reservas en el Rio Grande se puede observar segun los flujos de constituyentes discurren a 10 largo del rio. EI analisis de los flujos de constituyentes a escala de la cuenca proveera los medios para evaluar la influencia de la actividad humana sobre las condiciones de calidad del agua del Rio Grande.

  10. The influence of fluvial dynamics and North Atlantic swells on the beach habitat of leatherback turtles at Grande Riviere Trinidad.

    Science.gov (United States)

    Darsan, Junior; Jehu, Adam; Asmath, Hamish; Singh, Asha; Wilson, Matthew

    2016-09-15

    Grande Riviere beach, located on the north coast of Trinidad, West Indies, is internationally recognised as a critical habitat/nesting ground for the endangered leatherback turtles (Dermochelys coriacea). Episodic extreme flooding of the Grande Riviere River led to the shifting of the river mouth and resulted in backshore beach erosion, with the most recent recorded event occurring in 2012. Following this event, the construction of a sand dam to arrest further erosion which threatened coastal infrastructure, precipitated a host of new problems ranging from beach instability to public health threats. In January 2013, high energy swell waves naturally in-filled the erosion channel, and the beach recovery continued over the successive months, thereby rendering the intervention in the previous year questionable. This paper presents a geomorphological analysis of beach dynamics for Grande Riviere, within the context of this erosion event. Data on beach profiles, sediment and coastal processes were collected using standard geomorphological techniques. Beach topographic analysis and water quality tests on impounded water in the erosion channel were conducted. Results indicate that the event created an erosion channel of 4843.42 m(3) over a contiguous area of 2794.25 m(2). While swell waves were able to naturally infill the channel, they also eroded 17,762 m(3) of sand overall across the beach. Water quality tests revealed that the impounded water was classified as a pollutant, and created challenges for remediation. Hydrologic and coastal geomorphologic interplay is responsible for the existence and sustainability of this coastal system. It is also evident that the beach system is able to recover naturally following extreme events. Our results demonstrate that effective and integrated management of such critical habitats remains dependent upon continuous monitoring data which should be used to inform policy and decision making. PMID:27213864

  11. Grand Unification as a Bridge Between String Theory and Phenomenology

    Energy Technology Data Exchange (ETDEWEB)

    Pati, Jogesh C.

    2006-06-09

    In the first part of the talk, I explain what empirical evidence points to the need for having an effective grand unification-like symmetry possessing the symmetry SU(4)-color in 4D. If one assumes the premises of a future predictive theory including gravity--be it string/M theory or a reincarnation--this evidence then suggests that such a theory should lead to an effective grand unification-like symmetry as above in 4D, near the string-GUT-scale, rather than the standard model symmetry. Advantages of an effective supersymmetric G(224) = SU(2){sub L} x SU(2){sub R} x SU(4){sup c} or SO(10) symmetry in 4D in explaining (1) observed neutrino oscillations, (2) baryogenesis via leptogenesis, and (3) certain fermion mass-relations are noted. And certain distinguishing tests of a SUSY G(224) or SO(10)-framework involving CP and flavor violations (as in {mu} {yields} e{gamma}, {tau} {yields} {mu}{gamma}, edm's of the neutron and the electron) as well as proton decay are briefly mentioned. Recalling some of the successes we have had in our understanding of nature so far, and the current difficulties of string/M theory as regards the large multiplicity of string vacua, some comments are made on the traditional goal of understanding vis a vis the recently evolved view of landscape and anthropism.

  12. Geomorphology of plutonium in the Northern Rio Grande

    International Nuclear Information System (INIS)

    Nearly all of the plutonium in the natural environment of the Northern Rio Grande is associated with soils and sediment, and river processes account for most of the mobility of these materials. A composite regional budget for plutonium based on multi-decadal averages for sediment and plutonium movement shows that 90 percent of the plutonium moving into the system is from atmospheric fallout. The remaining 10 percent is from releases at Los Alamos. Annual variation in plutonium flux and storage exceeds 100 percent. The contribution to the plutonium budget from Los Alamos is associated with relatively coarse sediment which often behaves as bedload in the Rio Grande. Infusion of these materials into the main stream were largest in 1951, 1952, 1957, and 1968. Because of the schedule of delivery of plutonium to Los Alamos for experimentation and weapons manufacturing, the latter two years are probably the most important. Although the Los Alamos contribution to the entire plutonium budget was relatively small, in these four critical years it constituted 71--86 percent of the plutonium in bedload immediately downstream from Otowi

  13. Probing the design of grand unification through conservation laws

    International Nuclear Information System (INIS)

    The purpose of this talk is to note a few special consequences of gauging ''maximal'' quark-lepton symmetries such as SO(16), which is the maximal symmetry for a single family of fermions. Within these symmetries, violations for B, L and F are spontaneous rather than explicit. Furthermore these symmetries as a rule permit intermediate mass scales approx.(103-106 GeV) and (108-1011 GeV) filling the so-called grand plateau between 102 and 1015 GeV. It has been shown in earlier papers that within these symmetries proton may decay via four alternative models: i.e. proton→one or three leptons or antileptons plus mesons; some of which can coexist. It is now observed that even n-n-bar oscillations can coexist with (B-L) conserving proton-decays of the type p→e+π0 etc. without posing any conflict with the cosmological generation of baryon-excess; both these processes can possess measurable strengths so as to be amenable to forthcoming searches. Search for alternative decay modes of proton and n-n-bar oscillations, even as processes in second and third generation experiments, would provide valuable information on the question of intermediate mass-scales and thereby on the design of grand unification

  14. Towards a grand deal on subsidies and climate change

    International Nuclear Information System (INIS)

    Recent studies have identified public subsidies as a principal cause of unsustainable development. Worldwide, governments are spending up to $US950 billion a year on subsidies. Many of these public subsidies fail to serve their purpose and in fact, often turn out as policy failures as they further distort trade and cause environmental harm. The energy sector is among the most subsidized sectors in the world, receiving over $US240 billion per annum of public subsidies. This article highlights current energy subsidies and their implications. The article examines: (i) the global size and distribution of energy subsidies in industrialized and developing countries; (ii) the impact of these subsidies on the economy, equity and the environment ana their role as barriers for sustainable development; (iii) the political economy behind public subsidies and the various political and institutional barriers and lock-in mechanisms that cause subsidies to become entrenched in economic and public structures; and (iv) proposals for effective subsidy reform in energy policies, suggesting a global strategy to eliminate energy subsidies. OECD governments are in a position to take the lead, and the UN Framework Convention on Climate Change presents an excellent opportunity of striking a political grand deal and linking the reform of energy subsidies to a meaningful participation of developing countries to the Kyoto Protocol. Moreover, if sinks are to be included in the clean development mechanism (CDM), it is crucial to include the removal of forestry subsidies in the grand deal. (author)

  15. Geomorphology of plutonium in the Northern Rio Grande

    Energy Technology Data Exchange (ETDEWEB)

    Graf, W.L. [Arizona Univ., Tempe, AZ (United States). Dept., of Geography

    1993-03-01

    Nearly all of the plutonium in the natural environment of the Northern Rio Grande is associated with soils and sediment, and river processes account for most of the mobility of these materials. A composite regional budget for plutonium based on multi-decadal averages for sediment and plutonium movement shows that 90 percent of the plutonium moving into the system is from atmospheric fallout. The remaining 10 percent is from releases at Los Alamos. Annual variation in plutonium flux and storage exceeds 100 percent. The contribution to the plutonium budget from Los Alamos is associated with relatively coarse sediment which often behaves as bedload in the Rio Grande. Infusion of these materials into the main stream were largest in 1951, 1952, 1957, and 1968. Because of the schedule of delivery of plutonium to Los Alamos for experimentation and weapons manufacturing, the latter two years are probably the most important. Although the Los Alamos contribution to the entire plutonium budget was relatively small, in these four critical years it constituted 71--86 percent of the plutonium in bedload immediately downstream from Otowi.

  16. Female homicide in Rio Grande do Sul, Brazil

    Directory of Open Access Journals (Sweden)

    Gabriela Tomedi Leites

    2014-09-01

    Full Text Available This study aimed to assess the female homicide rate due to aggression in Rio Grande do Sul, Brazil, using this as a "proxy" of femicide. This was an ecological study which correlated the female homicide rate due to aggression in Rio Grande do Sul, according to the 35 microregions defined by the Brazilian Institute of Geography and Statistics (IBGE, with socioeconomic and demographic variables access and health indicators. Pearson's correlation test was performed with the selected variables. After this, multiple linear regressions were performed with variables with p < 0.20. The standardized average of female homicide rate due to aggression in the period from 2003 to 2007 was 3.1 obits per 100 thousand. After multiple regression analysis, the final model included male mortality due to aggression (p = 0.016, the percentage of hospital admissions for alcohol (p = 0.005 and the proportion of ill-defined deaths (p = 0.015. The model have an explanatory power of 39% (adjusted r2 = 0.391. The results are consistent with other studies and indicate a strong relationship between structural violence in society and violence against women, in addition to a higher incidence of female deaths in places with high alcohol hospitalization.

  17. kNN method on KASCADE-grande data

    International Nuclear Information System (INIS)

    KASCADE-grande, located at Forschungszentrum Karlsruhe, is a multi-detector experiment for the measurement of extensive air showers induced by primary cosmic rays in the energy range of 1014-1018 eV. The ''k-Nearest Neighbours'' (KNN) method is a classification procedure applied for a preliminary study of the cosmic ray composition in this energy range. Simulations of different primary particles are used as reference samples. In order to find for each real event the k-Nearest Neighbours in the reference sample, the Mahalanobis distance in the space defined by the muon size, the shower size and age (obtained from the NKG fit of the lateral distribution of the charged particles) is calculated. The probability of the event to be part of one of the simulated primary groups is the percentage of the k neighbours belonging to it. Preliminary results of the application of this technique to KASCADE-grande data with respect to simulated samples are reported

  18. SO(10) grand unified theory in generalized covariant derivative formalism

    International Nuclear Information System (INIS)

    The SO(10) grand unified theory is reformulated in a new field theory with a unified field strength for both the gauge and Higgs fields, and the fine-tuning problem and the condition for the symmetry breakings are investigated. The unified field strength for the gauge and Higgs fields, which takes values in the Dirac algebra, is defined by means of the commutator of the generalized covariant derivative for a multi-spinor field decreasing all families of quarks and leptons. The bosonic Lagrangian is constructed from a general sum of quadratic invariants of the field strength. Among the Yukawa coupling constants and other parameters related to the Higgs field self-couplings, there exist additional relations that are interpreted as initial conditions for renormalization equations. The grand unified symmetry is broken down to the low energy symmetry by the 210-, 45-, 126- and 10-dimensional Higgs fields. The Higgs potential turns out to have a discrete symmetry among Higgs fields. This symmetry makes it subtle and difficult to solve the fine-tuning problem, which required accurate adjustments of the parameters included in the generalized covariant derivative. It is shown that the 45-dimensional Higgs field plays an essential role to break the discrete symmetry and to solve the fine-tuning problem. (author)

  19. Flavour in supersymmetric Grand Unification a democratic approach

    CERN Document Server

    Barbieri, Riccardo; Dvali, Gia; Hall, L; Strumia, A

    1994-01-01

    We consider the flavour problem in a supersymmetric Grand Unified theory with gauged SU(6) group, where the Higgs doublets are understood as pseudo-Goldstone bosons of a larger $\\SU(6)\\otimes\\SU(6)$ global symmetry of the Higgs superpotential. A key element of this work is that we never appeal to any flavour symmetry. One main interesting feature emerges: only one of the light fermions, an up-type quark, to be identified with the top, can get a Yukawa coupling at renormalizable level. This fact, together with bottom-tau Yukawa unification, also implied in our scheme, gives rise to a characteristic correlation between the top and the Higgs mass. By including a flavour-blind discrete symmetry and requiring that all higher dimensional operators be mediated by the exchange of appropriate heavy multiplets, it is possible to give an approximate description of all masses and mixing angles in term of a hierarchy of grand unified scales. A special ``texture'' arises, implying a relation between the top mass and the th...

  20. Developing a Watershed Challenge

    Science.gov (United States)

    Roman, Harry T.

    2010-01-01

    This article presents a watershed challenge that gives students an opportunity to investigate the challenge of using a watershed area as a site for development, examining the many aspects of this multifaceted problem. This design challenge could work well in a team-based format, with students taking on specific aspects of the challenges and…

  1. Sleep bruxism: challenges and restorative solutions

    Directory of Open Access Journals (Sweden)

    Mengatto CM

    2016-04-01

    Full Text Available Cristiane Machado Mengatto, Fábio Herrmann Coelho-de-Souza, Oswaldo Baptista de Souza Junior Department of Conservative Dentistry, School of Dentistry, Federal University of Rio Grande do Sul (UFRGS, Porto Alegre, Brazil Abstract: Bruxism is a parafunctional activity related to clenching or grinding the teeth and tooth wear can be a consequence of sleep bruxism (SB. Management of severe tooth wear due to SB is a challenging situation because of the common reduced amount of remaining dental structure and loss of vertical dimension of occlusion. Rationale for the planning of oral rehabilitation of patients with SB presenting severe tooth wear should rely on evidence-based approaches; however, few studies have discussed properties of dental materials for SB rehabilitation and how to cosmetically manage severe tooth wear. This review aimed to provide an overview into bruxism cosmetic rehabilitation and how this can be implemented with good outcomes for the patient. Keywords: sleep bruxism, restoration, rehabilitation, prosthodontics, dentistry

  2. Completion of the uranium mill tailings remedial project and cleanup of the former mill site at Grand Junction, Colorado

    International Nuclear Information System (INIS)

    The United States Department of Energy's Uranium Mill Tailings Remedial Action (UMTRA) Surface Project has successfully completed the cleanup of 22 former uranium mill sites, more than 5400 vicinity properties, and has constructed 18 entombment cells. The Project has recently received the United States Nuclear Regulatory Commission's approval and certification for the last two disposal sites, with these sites being placed under the general license for long term custodial care of residual radioactive material. The UMTRA site located at Grand Junction, Colorado is a good example of the technical, political, economic, and public relations challenges that were overcome in achieving success. The UMTRA Team discussed, negotiated, planned, and eventually acted on this uranium mill tailings problem and brought the project to a successful conclusion for the community. From the early 1940s through the 1970s, uranium ore was mined in significant quantities under United States federal contracts for the government's national defence programmes, i.e. the Manhattan Engineering District and Atomic Energy Commission programmes. The problem started as the need for uranium decreased in the late 1960s, resulting in mills shutting down, leaving behind large quantities of process waste tailings and contaminated mill buildings. The former Climax Uranium Company mill site in Grand Junction was one of the largest of these sites. (author)

  3. Health assessment for Rio Grande Oil Company Refinery (Rio Grande I), National Priorities List, Sour Lake, Texas, Region 6. CERCLIS No. TXD980795736. Preliminary report

    Energy Technology Data Exchange (ETDEWEB)

    1990-05-16

    The Rio Grande Oil Company Refinery (Rio Grande I) site is a proposed National Priorities List site located adjacent to the City of Sour Lake in Hardin County, Texas. Rio Grande I was the site of an oil refinery in the 1920s and 1930s. Refinery wastes were disposed of on site in open, unlined pits. A privately-funded remediation effort removed 3,410 cubic yards of waste material from the site in November 1987. Elevated levels of mercury, zinc, and bis(2-ethylhexyl)phthalate were detected in soil on site after remediation. No groundwater contamination was detected. Based on the available environmental sampling information, the Rio Grande I site is not of public health concern under current conditions.

  4. Serologic response of Rio Grande wild turkeys to experimental infections of Mycoplasma gallisepticum

    Science.gov (United States)

    Rocke, Tonie E.; Yuill, Thomas M.

    1988-01-01

    The serologic response of Rio Grande wild turkeys (Meleagris gallopavo intermedia) to Mycoplasma gallisepticum (MG) was determined. Free-ranging turkeys were caught in southern Texas, shipped to the University of Wisconsin, Madison, and housed in isolation facilities. Fourteen birds were exposed to MG, by intratracheal and intranasal inoculation. Eight birds received sterile broth only. Two wk prior to the end of the experiment, MG exposed turkeys were stressed by challenge with a serologically unrelated mycoplasma. Serum from all exposed birds reacted positively for MG antibody by the rapid plate agglutination (RPA) procedure within 2 mo postexposure (PE) and all but one remained positive for 14 mo PE. Less than one half of the exposed birds developed positive MG antibody titers detectable by the hemagglutination inhibition (HI) test within 2 mo PE, and by 10 mo PE, none had positive titers. Antibody was detected by the HI test in two of 11 infected turkeys, 14 mo PE, and titers increased significantly within 2 wk. MG was isolated from tracheal swabs from two infected birds 2 mo PE, but attempts thereafter failed. However, at the termination of the experiment 15 mo later, MG was isolated from lung tissue of three of 11 exposed turkeys and from a blood clot found in the lower trachea of one bird.

  5. ‘Praise beyond Words’: Psalm 150 as grand finale of the crescendo in the Psalter

    Directory of Open Access Journals (Sweden)

    Dirk J. Human

    2011-06-01

    Full Text Available Without doubt the final hymn of the Psalter can be described as the climax, or grand finale, of the Israelite faith’s most known hymnbook. In this psalm, sound and action are blended into a picture of ecstatic joy. The whole universe is called upon to magnify Yah(weh, the God of Israel. The text poses various exegetical challenges. In the past, Psalm 150 was traditionally analysed as a single text; but with the advent of the canonical and redactionhistorical approaches to the interpretation of the Book of Psalms, Psalm 150 can be interpreted as part of the final Hallel (Pss 146–150, or Book V (Pss 107–150 of the Psalter. This view opens up new possibilities for reading the psalm in broader contexts and its broader literary context(s illuminate its theological significance. This article is an attempt at reflecting on the psalm’s context(s, structure, Gattung and dates of origin, tradition-historical relations to the Pentateuch, Psalms and other Old Testament texts. Ultimately some reflections on the psalm’s theological significance will be suggested.

  6. Grand Unification of AGN and the Accretion and Spin Paradigms

    CERN Document Server

    Meier, D L

    1999-01-01

    While attempts to unify certain classes of AGN using orientation and environmental effects have been successful, it is widely recognized that intrinsic properties of the accreting black hole system also must play a role in determining the appearance of such an object. In addition to mass and accretion rate, the angular momentum (or spin) of the black hole can play a crucial role in determining the power of a relativistic jet that is generated by magnetohydrodynamic acceleration near the hole. In this paper a scenario is presented, based on accretion theory and recent models of MHD jet production, in which the primary (although not only) parameter differentiating between radio loud and quiet objects is the black hole spin, and that determining quasar vs. radio galaxy is the accretion rate. A surprising number of desirable features result from these simple concepts and the accompanying equations. In addition, there are several testable predictions that can determine whether this grand unification scheme has fur...

  7. Grand Hotel a Villa Feltrinelli室内设计

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Grand Hotel a Villa Feltrinelli位于意大利北就伦巴第区Gargneno的Lake Gerda西岸。酒店建于1892年,由米兰建筑师Alberico Barbiano di Belogioioso以图书馆形式设计,此设计风格与“新艺术”一样同受前辈拉斐尔主义及新歌德主义影响。酒店外墙以金色及赤陶土色为主要用色。配合诺大窗户及小巧的城堡式阁楼为设计主线,体现出威尼斯宫殿的绝代风华。

  8. Eslabones encontrados: Los grandes simios y el imaginario occidental.

    OpenAIRE

    Beto Vianna; Rubén Gómez-Soriano

    2005-01-01

    Al menos desde la publicación en 1758 de la décima y seminal edición del Systema Naturae de Linneo, los grandes simios –orangutanes, gorilas, chimpancés y bonobos - han ocupado un sitio al mismo tiempo privilegiado e incómodo en el imaginario científico occidental. Privilegiado porque, incluso antes del consenso en la comunidad científica acerca de la evolución, ya ocupaban el lugar más próximo al ser humano dentro de la escala natural de los seres. Incómodo porque esa misma proximidad se ha ...

  9. Pre-cambrian geochronology in Rio Grande do Norte, Brazil

    International Nuclear Information System (INIS)

    The Precambrian region polyciclic caracter, in the Rio Grande do Norte State has make difficulties to its geochronological and geological studies. Four importants tectonometamorphic occurences identified dissimulate the original isotopic composition of the rocks. Is much defined the presence of three geochronological events wich left vestiges in the differents Serido litological units. The first event is related with Jequie cicle (2,7 b.y) and related with the Caico Group rocks. The second important event define the Transamazonic cicle (2.1 b.y). The third is correlated with Brazilian Cicle, when occurred the granitoids and pegmatites bodies formation. This third event was the last in this region and affect the other units too. (C.D.G.)

  10. Sensitivity of KASCADE-Grande data to hadronic interaction models

    CERN Document Server

    Kang, D; Arteaga-Velázquez, J C; Bekk, K; Bertaina, M; Blümer, J; Bozdog, H; Brancus, I M; Buchholz, P; Cantoni, E; Chiavassa, A; Cossavella, F; Daumiller, K; de Souza, V; di Pierro, F; Doll, P; Engel, R; Engler, J; Finger, M; Fuhrmann, D; Ghia, P L; Gils, H J; Glasstetter, R; Grupen, C; Haungs, A; Heck, D; Hörandel, J R; Huege, T; Isar, P G; Kampert, K -H; Kickelbick, D; Klages, H O; Link, K; Luczak, P; Ludwig, M; Mathes, H J; Mayer, H J; Melissas, M; Milke, J; Mitrica, B; Morello, C; Navarra, G; Nehls, S; Oehlschläger, J; Ostapchenko, S; Over, S; Palmieria, N; Petcu, M; Pierog, T; Rebel, H; Roth, M; Schieler, H; Schröder, F G; Sima, O; Toma, G; Trinchero, G C; Ulrich, H; Weindl, A; Wochele, J; Wommer, M; Zabierowski, J

    2010-01-01

    KASCADE-Grande is a large detector array dedicated for studies of high-energy cosmic rays in the primary energy range from 100 TeV to 1 EeV. The multi-detector concept of the experimental set-up offers the possibility to measure simultaneously various observables related to the electromagnetic, muonic, and hadronic air shower components. The experimental data are compared to predictions of CORSIKA simulations using high-energy hadronic interaction models (e.g. QGSJET or EPOS), as well as low-energy interaction models (e.g. FLUKA or GHEISHA). This contribution will summarize the results of such investigations. In particular, the validity of the new EPOS version 1.99 for EAS with energy around 100 PeV will be discussed.

  11. Grande Ronde Basin Fish Habitat Enhancement Project : 2007 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    McGowan, Vance R.; Morton, Winston H.

    2008-12-30

    On July 1, 1984 the Bonneville Power Administration and the Oregon Department of Fish and Wildlife entered into an intergovernmental contract to initiate fish habitat enhancement work in the Joseph Creek subbasin of the Grande Ronde River Basin in northeast Oregon. In 1985 the Upper and Middle Grande Ronde River, and Catherine Creek subbasins were included in the contract, and in 1996 the Wallowa River subbasin was added. The primary goal of 'The Grande Ronde Basin Fish Habitat Enhancement Project' is to create, protect, and restore riparian and instream habitat for anadromous salmonids, thereby maximizing opportunities for natural fish production within the basin. This project provided for implementation of Program Measure 703 (C)(1), Action Item 4.2 of the Northwest Power Planning Council's Columbia River Basin Fish and Wildlife Program (NPPC, 1987), and continues to be implemented as offsite mitigation for mainstem fishery losses caused by the Columbia River hydro-electric system. All work conducted by the Oregon Department of Fish and Wildlife and partners is on private lands and therefore requires that considerable time be spent developing rapport with landowners to gain acceptance of, and continued cooperation with this program throughout 10-15 year lease periods. Both passive and active restoration treatment techniques are used. Passive regeneration of habitat, using riparian exclosure fencing and alternate water sources are the primary method to restore degraded streams when restoration can be achieved primarily through changes in management. Active restoration techniques using plantings, bioengineering, site-specific instream structures, or whole stream channel alterations are utilized when streams are more severely degraded and not likely to recover in a reasonable timeframe. Individual projects contribute to and complement ecosystem and basin-wide watershed restoration efforts that are underway by state, federal, and tribal agencies, and

  12. Formulation of Liouville's theorem for grand ensemble molecular simulations

    Science.gov (United States)

    Delle Site, Luigi

    2016-02-01

    Liouville's theorem in a grand ensemble, that is for situations where a system is in equilibrium with a reservoir of energy and particles, is a subject that, to our knowledge, has not been explicitly treated in literature related to molecular simulation. Instead, Liouville's theorem, a central concept for the correct employment of molecular simulation techniques, is implicitly considered only within the framework of systems where the total number of particles is fixed. However, the pressing demand of applied science in treating open systems leads to the question of the existence and possible exact formulation of Liouville's theorem when the number of particles changes during the dynamical evolution of the system. The intention of this paper is to stimulate a debate about this crucial issue for molecular simulation.

  13. Bauchau (Henry), La Grande Muraille. Journal (1960-1965)

    OpenAIRE

    Halen, Pierre

    2013-01-01

    Jour après jour, le journal de la période 1983-1989, avait initialement été publié par les Éperonniers à Bruxelles ; il est aujourd’hui repris au catalogue d’Actes Sud, de même que le Journal d’Antigone pour la période 1989-1997. Aujourd’hui paraît, sous le titre de La Grande Muraille qui avait d’abord été retenu pour le roman La Déchirure (1966), le journal de la période 1960-1965. À lire ce troisième tome, relatif à l’époque décisive où Bauchau devient véritablement écrivain en composant so...

  14. STEM education for teachers in the Rio Grande Valley

    Science.gov (United States)

    Ries, Judit Gyorgyey; Baguio, Margaret R.

    2015-11-01

    We have worked with elementary and middle school teachers in the Rio Grande Valley for the last 10 years bringing Earth and Space Science themed workshops to underserved areas of Texas. The Texas curriculum was also changed to include Astronomy and Space Science requirement in the tests students need to take to prove their academic preparedness. The teachers worked through a variety of inquiry-based, hands-on activities after a short presentation on the background science. In order to evaluate our effectiveness, we have asked the teachers to take pre- and post-workshop tests, and we asked them to fill out a self-reflective survey. We will report on our experiences, what works best with the teachers, and in what areas we still have a long way to go.This work was supported by various NASA education grants and Cooperative agreements, as well as grants provided by the Texas Space Grant Consortium.

  15. Cochlear implantation in a patient with grand mal epilepsy.

    Science.gov (United States)

    Szilvassy, J; Czigner, J; Somogyi, I; Jori, J; Kiss, J G; Szilvassy, Z

    1998-06-01

    A case is reported in which a Nucleus 22 channel intracochlear implant was used to treat a deaf Hungarian woman (aged 37 years) with a 34-year history of grand mal (GM) epilepsy maintained on carbamazepine-diazepam combination therapy who had not benefited from conventional hearing aids. Pre-operative electrical stimulation of the acoustic nerve, however, exhibited a good nerve function with no evidence of abnormal waveforms in the electroencephalogram (EEG). Successful intracochlear insertion of the 22 electrode resulted in a 40 dB hearing improvement at frequencies 250-2000 Hz in the implanted ear with no signs of pathologic wave activity at either the previously recognized epileptic focus (fronto-precentral region) or indeed, in other regions of the brain at use of the implant. We conclude that intracochlear implantation per se is not a hazardous intervention in patients with fronto-precentral epileptic foci. PMID:9764299

  16. Pattern of neutrino mixing in grand unified theories

    International Nuclear Information System (INIS)

    It was found previously in SO(10) grand unified theories that if the neutrinos have a Dirac mass and a right-handed Majorana mass (approx. 1015GeV) but no left-handed Majorana mass, there is small ν/sub e/ mixing but ν/sub μ/ - ν/sub tau/ mixing can be substantial. This problem is reexamined on the basis of a formalism that assumes that the up, down, lepton, and neutrino mass matrices arise from a single complex 10 and a single 126 Higgs boson. This formalism determines the Majorana mass matrix in terms of quark mass matrices. Adopting three different sets of quark mass matrices that produce acceptable fermion mass ratios and Cabbibo mixing produces results consistent with the above; however, in the optimum case, ν/sub e/ - ν/sub μ/ mixing can be of the order of the Cabbibo angle

  17. From grand narratives of democracy to small expectations of participation

    DEFF Research Database (Denmark)

    Peters, Christopher; Witschge, Tamara

    2016-01-01

    distinctions based on structures of participation and different levels of engagement. This article argues that the focus in digital journalism is not so much on citizen engagement but rather audience or user interaction; instead of participation through news, the focus is on participation in news. This demands...... storytelling and distribution of citizen journalism within public discourse (integrative structural participation). Furthermore, commercial interests tend to dominate the shaping of digital affordances, which can lead to individualistic rather than collective conceptualisations. This article concludes by......This chapter critically examines the invocation of democracy in the discourse of audience participation in digital journalism. Rather than simply restate the familiar grand narratives that traditionally described journalism’s function for democracy (information source, watchdog, public...

  18. Molecular epidemiology of HIV-1 in Rio Grande, RS, Brazil

    Directory of Open Access Journals (Sweden)

    Martínez Ana Maria Barral de

    2002-01-01

    Full Text Available We conducted a molecular epidemiological study to investigate HIV-1 strains in Rio Grande, southern Brazil, searching for an association with transmission mode and risk behavior. Patients (185 identified at an AIDS treatment reference Hospital, from 1994 to 1997, were included; from which 107 blood samples were obtained. Nested PCR was realized once for each sample; for amplified samples (69 HIV subtypes were classified using the heteroduplex mobility assay. Subtypes identified were B (75%, C (22% and F (3%. All infections with C were diagnosed after 1994. Comparing patients with B and C, no differences were detected regarding demographic, clinical and laboratory characteristics; survival analysis did not reveal differences in HIV to AIDS evolution. A higher proportion of injecting drug users, IDU (not significant, p<.07 was found among those with C. This suggests that C may have been introduced in this area through IDU, and is being spread, probably by their sexual partners, to persons with other risk practices.

  19. 75 FR 20920 - Safety Zone; Lake Havasu Grand Prix, Lake Havasu, AZ

    Science.gov (United States)

    2010-04-22

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Lake Havasu Grand Prix, Lake Havasu, AZ... temporary safety zone upon the navigable waters of Lake Havasu on the Colorado River in Lake Havasu City, Arizona for the Lake Havasu Grand Prix. This temporary safety zone is necessary to provide for the...

  20. A study of the Forbush decrease event of September 11, 2005 with GRAND

    CERN Document Server

    Poirier, J; Hemphill, P; D'Andrea, C

    2008-01-01

    Project GRAND, a proportional wire chamber array, is used to examine the decreased counting rate of ground level muons during the Forbush decrease event of September 11, 2005. Data are presented and compared to that of other cosmic ray monitors. A directional study of the Forbush decrease was undertaken and precursor anisotropies to this geomagnetic storm were studied utilizing GRAND's angular resolution.

  1. 77 FR 49730 - Safety Zone; Antique Boat Show, Niagara River, Grand Island, NY

    Science.gov (United States)

    2012-08-17

    ... Safety Zone; Antique Boat Show, Niagara River, Grand Island, NY in the Federal Register (77 FR 13516). We... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Antique Boat Show, Niagara River, Grand... restrict vessels from a portion of the Niagara River during the Antique Boat Show powerboat races....

  2. 77 FR 37326 - Safety Zone; Grand Hotel 125th Anniversary Fireworks Celebration, Mackinaw Island, MI

    Science.gov (United States)

    2012-06-21

    .... SUPPLEMENTARY INFORMATION: Table of Acronyms DHS Department of Homeland Security FR Federal Register NPRM Notice... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Grand Hotel 125th Anniversary Fireworks... launched from a point on Lake Huron to commemorate the Grand Hotel's 125th anniversary. The Captain of...

  3. 33 CFR 100.720 - Annual Suncoast Offshore Grand Prix; Gulf of Mexico, Sarasota, FL.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Annual Suncoast Offshore Grand Prix; Gulf of Mexico, Sarasota, FL. 100.720 Section 100.720 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY REGATTAS AND MARINE PARADES SAFETY OF LIFE ON NAVIGABLE WATERS § 100.720 Annual Suncoast Offshore Grand Prix;...

  4. 33 CFR 208.25 - Pensacola Dam and Reservoir, Grand (Neosho) River, Okla.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Pensacola Dam and Reservoir, Grand (Neosho) River, Okla. 208.25 Section 208.25 Navigation and Navigable Waters CORPS OF ENGINEERS..., Grand (Neosho) River, Okla. The representative of the agency charged with the operation of the...

  5. Acoustic design and research on the auditorium of Shanghai Grand Theatre

    Institute of Scientific and Technical Information of China (English)

    ZHANG Kuisheng

    2000-01-01

    Shanghai Grand Theatre is a great modern theatre with the largest formula, the highest investment, the most advanced technique and excellent acoustic quality in China. This article mainly introduced Shanghai Grand Theatre's characteristics of formula, technical requirements of acoustic design of Auditorium, characteristics of figure design, reverberation control, acoustic simulation research, acoustic performance and subjective evaluation.

  6. 77 FR 22569 - Interconnection of the Grande Prairie Wind Farm, Holt County, NE

    Science.gov (United States)

    2012-04-16

    ... Creek Townships. Grande Prairie Wind proposes to build up to 266 wind turbines. Permanent disturbance for each wind turbine generator location would be approximately 0.25 acres. Grande Prairie Wind is considering a variety of wind turbine generator types, with capacities ranging from 1.5 to 2.4 MW. Each...

  7. Fatores associados ao atraso no desenvolvimento em crianças, Rio Grande, Rio Grande do Sul, Brasil Factores asociados con retraso en el desarrollo de los niños, Rio Grande, Rio Grande do Sul, Brasil Factors associated with delay in development in children, Rio Grande, Rio Grande do Sul, Brazil

    Directory of Open Access Journals (Sweden)

    Aline Alves Veleda

    2011-03-01

    Full Text Available Estudo analítico com o objetivo de avaliar os fatores associados ao atraso no desenvolvimento em crianças entre 8 a 12 meses de idade indicadas como de risco ao nascer no município do Rio Grande, Rio Grande do Sul, Brasil. Foram utilizados como instrumentos o Teste de Triagem de Desenvolvimento de Denver II (TTDD II, a avaliação antropométrica e questionários estruturados. Participaram 220 crianças consideradas de risco ou não ao nascer. Foi encontrada uma prevalência de 20,5% de suspeita de atraso no desenvolvimento neuropsicomotor. As crianças que apresentaram risco de um TTDD II suspeito faziam parte de famílias de mais baixa renda; eram filhos de mães que haviam realizado menos de seis consultas de pré-natal e apresentavam índice peso-idade inadequado. Os dados sugerem a necessidade de um replanejamento das políticas de saúde infantil, visto que outros critérios poderiam ser incluídos nas condições de risco para a criança ao nascer.Estudio analítico con el objetivo de evaluar los factores asociados al atraso en el desarrollo en niños de 8 a 12 meses de edad indicados como riesgo al nacer en el municipio de Rio Grande, RS, Brasil. Fueron utilizadas como herramientas la Prueba de Tamizaje del Desarrollo de Denver II, la evaluación antropométrica y cuestionarios estructurados. Participaron 220 niños considerados de riesgo o no al nacer. Fue encontrada una prevalencia del 20,5% de sospecha de atraso en el desarrollo neuropsicomotor. Los niños que presentaron riesgo de un DDST II sospechoso formaban parte de familias de más baja renta; eran hijos de madres que habían realizado menos de seis consultas de prenatal y presentaban índice peso-edad inadecuado. Los datos sugieren la necesidad de un replanteamiento de las políticas de salud infantil, así como otros criterios podrían ser inclusos en las condiciones de riesgo para el niño al nacer.This analytical study aims to evaluate the factors associated to

  8. Web-based Interactive Landform Simulation Model - Grand Canyon

    Science.gov (United States)

    Luo, W.; Pelletier, J. D.; Duffin, K.; Ormand, C. J.; Hung, W.; Iverson, E. A.; Shernoff, D.; Zhai, X.; Chowdary, A.

    2013-12-01

    Earth science educators need interactive tools to engage and enable students to better understand how Earth systems work over geologic time scales. The evolution of landforms is ripe for interactive, inquiry-based learning exercises because landforms exist all around us. The Web-based Interactive Landform Simulation Model - Grand Canyon (WILSIM-GC, http://serc.carleton.edu/landform/) is a continuation and upgrade of the simple cellular automata (CA) rule-based model (WILSIM-CA, http://www.niu.edu/landform/) that can be accessed from anywhere with an Internet connection. Major improvements in WILSIM-GC include adopting a physically based model and the latest Java technology. The physically based model is incorporated to illustrate the fluvial processes involved in land-sculpting pertaining to the development and evolution of one of the most famous landforms on Earth: the Grand Canyon. It is hoped that this focus on a famous and specific landscape will attract greater student interest and provide opportunities for students to learn not only how different processes interact to form the landform we observe today, but also how models and data are used together to enhance our understanding of the processes involved. The latest development in Java technology (such as Java OpenGL for access to ubiquitous fast graphics hardware, Trusted Applet for file input and output, and multithreaded ability to take advantage of modern multi-core CPUs) are incorporated into building WILSIM-GC and active, standards-aligned curricula materials guided by educational psychology theory on science learning will be developed to accompany the model. This project is funded NSF-TUES program.

  9. Magnetotelluric pilot study in the Rio Grande Rift, southwest USA

    Science.gov (United States)

    Feucht, D. W.; Bedrosian, P. A.; Sheehan, A. F.

    2012-12-01

    A magnetotelluric (MT) pilot study consisting of approximately 25 stations distributed in and around the Rio Grande Rift of the southwest United States was carried out in the summer of 2012. Both broadband (100 Hz to 1000 s) and long-period (up to 10 000 s) MT data were collected across two profiles that run perpendicular to the rift axis near Denver, Colorado and Taos, New Mexico, respectively. Time-domain EM data was also collected at each site to account for galvanic distortion in the near-surface. The tectonic forces and rheologic properties behind the initiation and propagation of the rift are poorly understood. Surface mapping of volcanism, normal faulting and sedimentary basins reveals a narrow band of crustal deformation confined to a region in close proximity to the rift axis while geophysical results suggest that deformation is distributed across a much broader and deeper region of the lithosphere. In particular, seismic tomography shows low seismic wave speeds into the lower crust and upper mantle. The magnetotelluric technique is a well-proven passive electromagnetic method that allows for the detection of apparent resistivity at a wide range of depth scales. Complimenting the seismic results with MT data will provide important new information on the geologic and geophysical properties that control the rifting process in this low-strain rate environment. Properties to which the MT method is particular sensitive include temperature, fluid content, and mineral alteration. Preliminary results from this most recent survey are encouraging, showing good data quality up to 10 000 s. In an important precursor to full 2D modeling, the magnetotelluric phase tensor has been used to assess the dimensionality of the electrical resistivity structure at depth. This pilot study provides proof of concept for a much larger magnetotelluric experiment planned to take place in the Rio Grande Rift in 2013.

  10. 78 FR 49296 - Centennial Challenges 2014 Sample Return Robot Challenge

    Science.gov (United States)

    2013-08-13

    ... SPACE ADMINISTRATION Centennial Challenges 2014 Sample Return Robot Challenge AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of Centennial Challenges 2014 Sample Return Robot... Robot Challenge is scheduled and teams that wish to compete may register. Centennial Challenges is...

  11. Parasitism and body condition in humpback chub from the Colorado and Little Colorado Rivers, Grand Canyon, Arizona

    Science.gov (United States)

    Hoffnagle, T.; Choudhury, Anindo; Cole, R.A.

    2006-01-01

    Glen Canyon Dam has greatly altered the Colorado River in Grand Canyon. The Little Colorado River (LCR) provides a small refuge of seasonally warm and turbid water that is thought to be more suitable than the Colorado River for endangered humpback chub Gila cypha. However, the LCR has low productivity and contains nonnative fishes and parasites, which pose a threat to humpback chub. The Colorado River hosts a different suite of nonnative fishes and is cold and clear but more productive. We compared condition factor (K), abdominal fat index (AFI), and presence and number of two introduced pathogenic parasites (Lernaea cyprinacea and Bothriocephalus acheilognathi) between juvenile (parasitism and poorer body condition in humpback chub from the LCR challenge the paradigm that warmer LCR waters are more suitable for humpback chub than the colder Colorado River and indicate the need to consider the importance and benefits of all available habitats, as well as biotic and abiotic factors, when managing endangered species and their environment.

  12. Harnessing the hydropower potential in Africa: What should be the place and role of Grand Inga hydropower project?

    Energy Technology Data Exchange (ETDEWEB)

    Fall, Latsoucabe

    2010-09-15

    Harnessing Africa's huge hydropower potential should be made a priority for the sustainable development of the Continent. Particularly, Grand Inga hydropower project in DRC, due to its gigantic size (40,000 MW) and favourable natural characteristics, could be 'Africa's flagship Project of the 21st Century' offering enormous comparative advantages and opportunities for the benefits of the entire African Continent. Nevertheless, to make it a feasible and palpable 'Model Project', capable of producing clean and affordable energy, the paper tries to respond to key questions on the several daunting challenges to address for its sustainable, cost-effective and timely development and operation.

  13. A FADC-based Data Acquisition System for the KASCADE-Grande Experiment

    CERN Document Server

    Walkowiak, W; Apel, W D; Badea, F; Bekk, K; Bercuci, A; Bertaina, M; Blümer, H; Bozdog, H; Brancus, I M; Bruggemann, M; Buchholz, P; Büttner, C; Chiavassa, A; Daumiller, K; di Pierro, F; Doll, P; Engel, R; Engler, J; Feler, F; Ghia, P L; Gils, H J; Glasstetter, R; Haungs, A; Heck, D; Hörandel, J R; Kampert, K H; Klages, H O; Kolotaev, Yu; Maier, G; Mathes, H J; Mayer, H J; Milke, J; Mitrica, B; Morello, C; Müller, M; Navarra, G; Obenland, R; Oehlschläger, J; Ostapchenko, S; Over, S; Petcu, M; Plewnia, S; Rebel, H; Risse, A; Roth, M; Schieler, H; Scholz, J; Stumpert, M; Thouw, T; Toma, G; Trinchero, G C; Ulrich, H; Valchierotti, S; Van Buren, J; Weindl, A; Wochele, J; Zabierowski, J; Zagromski, S; Zimmermann, D

    2006-01-01

    We present the design and first test results of a new FADC-based data acquisition (DAQ) system for the Grande array of the KASCADE-Grande experiment. The original KASCADE experiment at the Forschungszentrum Karlsruhe, Germany, has been extended by 37 detector stations of the former EAS-TOP experiment (Grande array)to provide sensitivity to energies of primary particles from the cosmos of up to $10^{18}$ eV. The new FADC-based DAQ system will improve the quality of the data taken by the Grande array by digitizing the scintillator signals with a 250 MHz sampling rate. events per second. Two Grande stations have been equipped with the FADC-based data acquisition system and first data are shown.

  14. Challenges of Parenting Multiples

    Science.gov (United States)

    ... the American Society for Reproductive Medicine Challenges of Parenting Multiples There are many psychological, social, and economic ... the unique challenges and rewards that come from parenting multiples. For more information on the medical aspects ...

  15. Overcoming Breastfeeding Challenges

    Medline Plus

    Full Text Available ... on Women's Health Skip Navigation Skip top navigation Home A-Z Health Topics ePublications News About Us ... Only Natural email updates. Enter email address Submit Home > It's Only Natural > Overcoming challenges Overcoming breastfeeding challenges ...

  16. Overcoming Breastfeeding Challenges

    Medline Plus

    Full Text Available ... size | Print | Skip left navigation It's Only Natural Planning ahead Overcoming challenges Overcoming breastfeeding challenges Dealing with lack of family support Is my baby getting enough milk? Breastfeeding ...

  17. Overcoming Breastfeeding Challenges

    Medline Plus

    Full Text Available A project of the U.S. Department of Health and Human Services Office on Women's Health Skip Navigation ... challenges Overcoming breastfeeding challenges Dealing with lack of family support Is my baby getting enough ...

  18. The Backpack Design Challenge

    Science.gov (United States)

    Roman, Harry T.

    2010-01-01

    Something as simple as carrying books to school can be an interesting design challenge for students. It's an old problem that gets reinvented from time to time. In this article, the author discusses a backpack design challenge in which teachers work with students to design another way to carry books to school. The challenge started by trying to…

  19. 76 FR 15936 - Designation for the Owensboro, KY; Bloomington, IL; Iowa Falls, IA; Casa Grande, AZ; Fargo, ND...

    Science.gov (United States)

    2011-03-22

    ... hours (7 CFR 1.27(c)). SUPPLEMENTARY INFORMATION: In the August 30, 2010, Federal Register (75 FR 52925..., IL; Iowa Falls, IA; Casa Grande, AZ; Fargo, ND; Grand Forks, ND; and Plainview, TX Areas...

  20. Wicked Challenges in the Anthropocene Age: Supply Chain Implications of Sustainable Enterprise Excellence

    DEFF Research Database (Denmark)

    Edgeman, Rick; Wu, Zhaohui

    , and desertification; food availability and distribution; water pollution, air pollution, and soil contamination; and the connection of these to disease, violence, and terrorism. Wicked challenge traits are discussed in relation to enterprise excellence, sustainability, resilience and robustness (SEER2). The value......Grand global challenges include wicked sustainability ones associated with human influences. Among these are climate change in relation to increased atmospheric presence of CO2 and methane, global warming and increasing intensity and incidence rates of extreme weather events, drought...... of SEER2 and selected of its enablers – especially supply chain proficiency – in addressing intersections of selected wicked sustainability challenges are highlighted....