WorldWideScience

Sample records for biopsies quality control

  1. Mapping of transrectal ultrasonographic prostate biopsies: quality control and learning curve assessment by image processing

    CERN Document Server

    Mozer, Pierre; Chevreau, Gregoire; Moreau-Gaudry, Alexandre; Bart, Stephane; Renard-Penna, Raphaele; Comperat, Eva; Conort, Pierre; Bitker, Marc-Olivier; Chartier-Kastler, Emmanuel; Richard, Francois; Troccaz, Jocelyne

    2009-01-01

    Objective: Mapping of transrectal ultrasonographic (TRUS) prostate biopsies is of fundamental importance for either diagnostic purposes or the management and treatment of prostate cancer, but the localization of the cores seems inaccurate. Our objective was to evaluate the capacities of an operator to plan transrectal prostate biopsies under 2-dimensional TRUS guidance using a registration algorithm to represent the localization of biopsies in a reference 3-dimensional ultrasonographic volume. Methods: Thirty-two patients underwent a series of 12 prostate biopsies under local anesthesia performed by 1 operator using a TRUS probe combined with specific third-party software to verify that the biopsies were indeed conducted within the planned targets. RESULTS: The operator reached 71% of the planned targets with substantial variability that depended on their localization (100% success rate for targets in the middle and right parasagittal parts versus 53% for targets in the left lateral base). Feedback from this ...

  2. Biopsies

    Science.gov (United States)

    ... News Physician Resources Professions Site Index A-Z Biopsies - Overview A biopsy is the removal of tissue ... What are the limitations of biopsies? What are biopsies? A biopsy is the removal of tissue in ...

  3. Needle localization breast biopsy: a model for multidisciplinary quality assurance.

    Science.gov (United States)

    Howe, J R; Monsees, B; Destouet, J; Seib, J; Dehner, L P; Kraybill, W G

    1995-04-01

    As part of the quality assurance role of the Cancer Committee at Barnes Hospital, an institutional audit of Needle Localization Breast Biopsy (NLBB) was performed. Mammographic, operative, and surgical pathology reports from 370 consecutive patients at our institution undergoing both mammography and needle localization biopsy over a 34-month interval were reviewed. Carcinoma was diagnosed pathologically in 103 patients (28%), and 27% of these proved to be noninvasive. Sixteen patients were found to have histologic or clinical involvement of the axillary nodes; no patients with Tis lesions were found to have axillary nodal involvement. Of the patients, 73% were found to have either Stage 0 or Stage I disease, and 61% with an established malignancy had mastectomy (67% of patients with invasive carcinoma, 44% of those with carcinoma-in-situ), whereas 39% had some form of conservation therapy (33% of patients with invasive lesions, 56% of those with carcinoma-in-situ). Our results have been compared with other published studies, and important clinical indicators for evaluating the results of individual centers performing NLBB are discussed. It is concluded that NLBB is a safe and effective method of biopsying nonpalpable breast lesions, which allows for the identification of early stage breast carcinomas. In the present environment of concerns about the quality of care and costs, it is the responsibility of each center performing NLBB periodically to evaluate their results with this multidisciplinary procedure and to bring about change in those areas found to be deficient. PMID:7723366

  4. Endoscopic biopsy as quality assurance for endoscopic services.

    Directory of Open Access Journals (Sweden)

    King-Wah Chiu

    Full Text Available Gastroendoscopy (GS procedures are not only performed by gastroenterologists (GE but also by hepatologists (HT in many countries. Endoscopic biopsy (EBx remains the gold standard for the investigation and documentation of esophago-gastro-duodenal pathology. EBx is subjectively performed by an endoscopist, and the level of skill and experience of the endoscopist may affect the quality of the endoscopic service. Reasons for this discrepancy included lack of experience practitioners to order EBx when required of GS issues between in GE and HT limit access. Ideally, services should be safe and of high quality. This study assessed the EBx/GS ratio as the endoscopic quality assurance as an index of GS services. This was a cohort study of endoscopists at Kaohsiung Chang Gung Memorial Hospital, a teaching hospital in southern Taiwan. There were 34,570 episodes of EBx in 199,877 GS procedures. The 25 endoscopists were divided into GE (n = 13 and HT (n = 12 groups, and correlation coefficients were calculated over a 14.5-year duration of intervention. The Trimmean of EBx/GS was 19.29% in 14.5 years (34570/199877 with Trimmean 0.2 percentile ratio correlations, and the Pearson correlation coefficient was 0.90229. There were significantly more EBx procedures in the GE group than in the HT group at 1 and 5 years (21.5% vs. 15.1% and 20.9% vs. 17.3%, respectively, P<0.00001. Junior GE attempted significantly more EBx than both the senior GE (24.06% vs. 20.41%, P<0.0001, and junior HT (24.06% vs. 13.2%, P<0.0001. In conclusion, quality assurance for gastrointestinal endoscopy involves numerous aspects of unit management and patient safety. Quality measures used with the EBx/GS ratio may be one of the best ways to ensure the quality of endoscopic procedures in a teaching hospital.

  5. [Does the mounting of gastrointestinal biopsies on millipore filter contribute to an improved section quality?

    DEFF Research Database (Denmark)

    Asmussen, L.; Bernstein, I.; Matzen, P.;

    2009-01-01

    INTRODUCTION: The quality of the histological sections of gastrointestinal biopsies (GIB) affects the diagnostic possibilities. One aspect is the orientation of GIB, whereby sectioning perpendicular to the mucosal surface can be performed more readily. With the purpose to achieve correct orientat......INTRODUCTION: The quality of the histological sections of gastrointestinal biopsies (GIB) affects the diagnostic possibilities. One aspect is the orientation of GIB, whereby sectioning perpendicular to the mucosal surface can be performed more readily. With the purpose to achieve correct...

  6. Diagnosing non-palpable breast disease : short-term impact on quality of life of large-core needle biopsy versus open breast biopsy

    NARCIS (Netherlands)

    Verkooijen, HM; Buskens, E; Peeters, PHM; Rinkes, IHMB; de Koning, HJ; van Vroonhoven, TJMV

    2002-01-01

    Background: One of the alleged advantages of stereotactic large-core needle biopsy of non-palpable breast lesions is that it entails less inconvenience for the patient. In this prospective study, the quality of life of patients undergoing large-core needle biopsy was compared with that of patients u

  7. Quality Control Applications

    CERN Document Server

    Chorafas, Dimitris N

    2013-01-01

    Quality control is a constant priority in electrical, mechanical, aeronautical, and nuclear engineering – as well as in the vast domain of electronics, from home appliances to computers and telecommunications. Quality Control Applications provides guidance and valuable insight into quality control policies; their methods, their implementation, constant observation and associated technical audits. What has previously been a mostly mathematical topic is translated here for engineers concerned with the practical implementation of quality control. Once the fundamentals of quality control are established, Quality Control Applications goes on to develop this knowledge and explain how to apply it in the most effective way. Techniques are described and supported using relevant, real-life, case studies to provide detail and clarity for those without a mathematical background. Among the many practical examples, two case studies dramatize the importance of quality assurance: A shot-by-shot analysis of the errors made ...

  8. Software product quality control

    CERN Document Server

    Wagner, Stefan

    2013-01-01

    Quality is not a fixed or universal property of software; it depends on the context and goals of its stakeholders. Hence, when you want to develop a high-quality software system, the first step must be a clear and precise specification of quality. Yet even if you get it right and complete, you can be sure that it will become invalid over time. So the only solution is continuous quality control: the steady and explicit evaluation of a product's properties with respect to its updated quality goals.This book guides you in setting up and running continuous quality control in your environment. Star

  9. Mammotome biopsy under ultrasound control in the diagnostics and treatment of nodular breast lesions - own experience.

    Science.gov (United States)

    Kibil, Wojciech; Hodorowicz-Zaniewska, Diana; Kulig, Jan

    2012-05-01

    Mammotome biopsy is an effective, minimally invasive, novel technique used in the verification of breast lesions.The aim of the study was to assess the value of ultrasound-guided vacuum-assisted core needle biopsy (mammotome biopsy) in the diagnostics and treatment of nodular breast lesions, considering own data.Material and methods. Analysis comprised 1183 mammotome biopsies under ultrasound control performed in 1177 female patients during the period between 2000 and 2010, at the Regional Clinic for Early Diagnostics and Treatment of Breast Lesions, I Chair and Department of General Surgery, Jagiellonian University, Collegium Medicum.Results. The average patient age amounted to 41.7 years. The size of the investigated lesions ranged between 4 and 65 mm (mean - 12 mm). The histopathological examination result was as follows: fibrocystic lesions (n=285), adenofibroma (n=477), adenosis sclerosans (n=188), hyperplasia without atypy (n=58), phyllode tumor (n=2), papilloma (n=14), hamartoma (n=1), atypical hyperplasia (n=25), in situ ductal carcinoma (n=4), in situ lobular carcinoma (n=5), infiltrating ductal carcinoma (n=114), infiltrating lobular carcinoma (n=4), non-diagnostic result (n=6). The histopathological diagnosis was obtained in 99.5% of cases. Patients diagnosed with atypical hyperplasia or cancer were qualified for surgery, according to accepted standards. The presence of a hematoma was the most common complication after the biopsy, observed in 16.5% of patients.Conclusions. The obtained results confirmed the high value of ultrasound-guided biopsies in the diagnostics of nodular breast lesions. The method is safe, minimally invasive, with few complications, providing a good cosmetic effect. In case of benign lesions with a diameter of less than 15 mm the mammotome biopsy enables to completely excise the lesions, being an alternative to open surgical biopsies. The mammotome biopsy should become the method of choice considering the diagnostics of nodular

  10. Checking quality control?

    DEFF Research Database (Denmark)

    Brodersen, Lars

    2005-01-01

    How is quality control doing within the community of GIS, web-services based on geo-information, GI etc.?......How is quality control doing within the community of GIS, web-services based on geo-information, GI etc.?...

  11. Evaluation of an interactive breath-hold control system in CT-guided lung biopsy

    International Nuclear Information System (INIS)

    Purpose: In this study we assessed the effect of an interactive breath-hold control system on procedure time and technical success in transthoracic CT-guided lung biopsies. Materials and Methods: in 36 patients (4 female, 32 male, mean age 65 years; range 33 - 88) with a pulmonary nodule, we performed CT-guided biopsy using a 18G Tru-cut needle (Cardinal Health, Dublin, UK) in a 64 row dual-source CT scanner (Somatom Definition, Siemens, Forchheim, Germany) using intermittent imaging of the needle. In half of the patients (2 female, 16 male, mean age 67 years), an interactive breathhold control system (IBC) (Mayo Clinic Medical Devices, USA) was applied. No additional device was used in the control group. Results: the biopsy was visually successful in all patients. The diameter of the target lesion was comparable in both groups (IBC: 30 ± 19 mm; control: 28 ± 15 mm). The number of imaging steps was significantly smaller (p < 0.05) and the intervention time was significantly shorter (p < 0.05) in the IBC group (IBC: 9 ± 5 steps 17 ± 10 min; control: 13 ± 5 steps 26 ± 12 min). Conclusion: application of the IBC unit reduced the intervention time and radiation exposure in CT-guided Tru-cut biopsy of pulmonary nodules. (orig.)

  12. Quality control of radiopharmaceuticals

    International Nuclear Information System (INIS)

    Quality assurance was introduced in the pharmaceutical field long before it was used in many other areas, and the term quality control has been used in a much broader sense than merely analytical quality control. The term Good Manufacturing Practice (GMP) has been used to describe the system used for producing safe and effective drugs of a uniform quality. GMP has also been used for the industrial production of radiopharmaceuticals. For the preparation and control of radiopharmaceuticals in hospitals a similar system has been named Good Radiopharmacy Practice (GRP). It contains the same elements as GMP but takes into account the special nature of this group of drugs. Data on the assessment of the quality of radiopharmaceuticals in relation to present standards are reviewed. The general conclusion is that the quality of radiopharmaceuticals appears comparable to that of other drugs. It seems possible to establish the production of radiopharmaceuticals, generators and preparation kits in such a way that analytical control of the final product at the hospital may be limited provided the final preparation work is carried out in accordance with GRP principles. The elements of GRP are reviewed. (author)

  13. Fine needle aspiration biopsy under computed tomographic control of mediastinal lesions - our 4 years experience

    International Nuclear Information System (INIS)

    The article presents our experience in the field of invasive diagnosis of mediastinal lesions for the period 2001-2004. We discuss the problems of marking the lesion, speeding the procedure and the complication risk. 69 patients (40 women and 29 men, age range 28-71) underwent fine needle aspiration biopsies (FNAB) under CT-control. We carried out the biopsies by cutting needles 22 G, under control of GE Sytec 3000 and Somaton Emotion Siemens. 58 biopsies were suitable for both cytological and histological diagnosis and 11 were obtained only cytological diagnosis. In 53 cases the material was collected from the very first insertion of the needle while in the other 16 cases a correction of the biopsy angle and/or zone under CT was performed. Six patients had a partial pneumothorax as a complication and no one had a haemothorax. Conclusion: the accurate placement of the needle tip within the lesion is difficult even under the control of the modern computed tomography due to: 1) adjacent bone (ribs, sternum); 2) passing through pulmonary tissue thick more than 3 cm. (authors)

  14. Quality Management, Quality Assurance and Quality Control in Blood Establishments

    OpenAIRE

    Bolbate, N

    2008-01-01

    Quality terms and the roots of the matter are analyzed according to European Committee’s recommendations. Essence of process and product quality control as well as essence of quality assurance is described. Quality system’s structure including quality control, quality assurance and management is justified in the article.

  15. Bone Biopsy

    Science.gov (United States)

    ... Physician Resources Professions Site Index A-Z Bone Biopsy Bone biopsy uses a needle and imaging guidance ... limitations of Bone Biopsy? What is a Bone Biopsy? A bone biopsy is an image-guided procedure ...

  16. Effect of endometrial biopsy on intrauterine insemination outcome in controlled ovarian stimulation cycle

    OpenAIRE

    Leena Wadhwa; Amrita Pritam; Taru Gupta; Sangeeta Gupta; Sarika Arora; Rajkumar Chandoke

    2015-01-01

    OBJECTIVE: The objective was to evaluate the effect of endometrial biopsy (EB) on intrauterine insemination (IUI) outcome in controlled ovarian stimulation (COS) cycle. DESIGN: Prospective randomized control study. SETTING: Tertiary care center. MATERIALS AND METHODS: A total of 251 subjects were enrolled in the study. Subjects undergoing COS with IUI were randomly allocated into three groups. Group A: EB was taken between D19 and 24 of the spontaneous menstrual cycles that precedes the ferti...

  17. MR imaging-guided vacuum-assisted breast biopsy: Reduction of false-negative biopsies by short-term control MRI 24–48 h after biopsy

    International Nuclear Information System (INIS)

    Aim: To evaluate whether another contrast-enhanced (CE) magnetic resonance imaging (MRI) examination 24–48 h after MRI-guided vacuum-assisted breast biopsy (MRI-VAB) can reduce the rate of false-negative cases. Materials and methods: The study included 252 patients who underwent MRI-VAB for the clarification of 299 lesions. The success of MRI-VAB was assessed at interventional MRI and another CE MRI 24–48 h after the intervention. In cases of successful MRI-VAB (complete or partial lesion removal) and benign histological results, follow-up breast MRI was performed. In cases of unsuccessful biopsy (unchanged lesion), tissue sampling was repeated. False-negative cases were calculated to assess the diagnostic value of MRI follow-up within 2 days after intervention. Results: Ninety-eight malignant (32.8%) and 201 (67.2%) benign lesions were diagnosed using MRI-VAB. At immediate unenhanced control MRI, all lesions were assessed as successfully biopsied. In 18 benign cases (6%), CE MRI after 24–48 h showed an unsuccessful intervention. Further tissue sampling revealed another 13 cancers in these patients. This results in a false-negative rate of 11.7%. Follow-up MRI of the benign lesions presented no further malignancy. Conclusions: MRI-VAB with immediate unenhanced control offers a success rate of 94%. The rate of false-negative biopsies (11.7%) could be reduced to zero by using short-term follow-up MRI. Therefore, a further CE breast MRI 24–48 h after benign MRI-VAB to eliminate missed cancers is recommended. - Highlights: • Some suspicious breast lesions are only seen on MRI. • They can be biopsied by a MRI-guided vacuum-assisted biopsy system. • Inadequate sampling causes some false-negative biopsies. • We evaluate an additional control MRI 24 to 48 hours after biopsy. • A reduced rate of the false-negative biopsies was found

  18. VGI QUALITY CONTROL

    Directory of Open Access Journals (Sweden)

    C. C. Fonte

    2015-08-01

    Full Text Available This paper presents a framework for considering quality control of volunteered geographic information (VGI. Different issues need to be considered during the conception, acquisition and post-acquisition phases of VGI creation. This includes items such as collecting metadata on the volunteer, providing suitable training, giving corrective feedback during the mapping process and use of control data, among others. Two examples of VGI data collection are then considered with respect to this quality control framework, i.e. VGI data collection by National Mapping Agencies and by the most recent Geo-Wiki tool, a game called Cropland Capture. Although good practices are beginning to emerge, there is still the need for the development and sharing of best practice, especially if VGI is to be integrated with authoritative map products or used for calibration and/or validation of land cover in the future.

  19. Quality control review: implementing a scientifically based quality control system.

    Science.gov (United States)

    Westgard, James O; Westgard, Sten A

    2016-01-01

    This review focuses on statistical quality control in the context of a quality management system. It describes the use of a 'Sigma-metric' for validating the performance of a new examination procedure, developing a total quality control strategy, selecting a statistical quality control procedure and monitoring ongoing quality on the sigma scale. Acceptable method performance is a prerequisite to the design and implementation of statistical quality control procedures. Statistical quality control can only monitor performance, and when properly designed, alert analysts to the presence of additional errors that occur because of unstable performance. A new statistical quality control planning tool, called 'Westgard Sigma Rules,' provides a simple and quick way for selecting control rules and the number of control measurements needed to detect medically important errors. The concept of a quality control plan is described, along with alternative adaptations of a total quality control plan and a risk-based individualized quality control plan. Finally, the ongoing monitoring of analytic performance and test quality are discussed, including determination of measurement uncertainty from statistical quality control data collected under intermediate precision conditions and bias determined from proficiency testing/external quality assessment surveys. A new graphical tool, called the Sigma Quality Assessment Chart, is recommended for demonstrating the quality of current examination procedures on the sigma scale. PMID:26150675

  20. Capillary Versus Aspiration Biopsy: Effect of Needle Size and Length on the Cytopathological Specimen Quality

    International Nuclear Information System (INIS)

    Purpose: To test the value of the nonaspiration, or capillary, biopsy technique by experimental comparison with the conventional fine-needle aspiration technique using various needle gauges and lengths. Methods: On fresh hepatic and renal tissue from five autopsies, multiple biopsy specimens were taken with 20, 22, and 23-gauge Chiba needles of 5, 10, 15, and 20-cm length, using the aspiration technique and the capillary technique. The resultant specimens were graded on the basis of a grading scheme by a cytopathologist who was blinded to the biopsy technique. Results: The capillary technique obtained less background blood or clot which could obscure diagnostic tissue, although not significantly different from the aspiration technique (p= 0.2). However, for the amount of cellular material obtained, retention of appropriate architecture, and mean score, the capillary technique performed statistically worse than aspiration biopsy (p < 0.01). In addition, with decreasing needle caliber (increasing needle gauge) and increasing length, the capillary biopsy was inferior to the aspiration biopsy. Conclusion: The capillary biopsy technique is inferior to the aspiration technique according to our study. When the capillary technique is to be applied, preference should be given to larger caliber, shorter needles

  1. Testicular biopsy

    Science.gov (United States)

    Biopsy - testicle ... The biopsy can be done in many ways. The type of biopsy you have depends on the reason for the ... will talk to you about your options. Open biopsy may be done in the health care provider's ...

  2. Gum biopsy

    Science.gov (United States)

    Biopsy - gingiva (gums) ... used to close the opening created for the biopsy. ... to eat for a few hours before the biopsy. ... Risks for this procedure include: Bleeding from the biopsy site Infection of the gums Soreness

  3. Liver biopsy

    Science.gov (United States)

    Biopsy - liver; Percutaneous biopsy ... prevent pain or to calm you (sedative). The biopsy may be done through the abdominal wall: You ... provider will find the correct spot for the biopsy needle to be inserted into the liver. This ...

  4. Optimizing control of quality management

    OpenAIRE

    Fliginskih Tatyana Nikolayevna; Fedoretc Ksenia Sergeevna

    2012-01-01

    This paper describes the technology that permits controlling of business processes in industry. An example of the use of control charts as one of the most effective methods of statistical quality control of products. The author provides a definition that best reveals the understanding of quality and quality control.

  5. Optimizing control of quality management

    Directory of Open Access Journals (Sweden)

    Fliginskih Tatyana Nikolayevna

    2012-05-01

    Full Text Available This paper describes the technology that permits controlling of business processes in industry. An example of the use of control charts as one of the most effective methods of statistical quality control of products. The author provides a definition that best reveals the understanding of quality and quality control.

  6. The effectivity of periprostatic nerve blockade for the pain control during transrectal ultrasound guided prostate biopsy

    Directory of Open Access Journals (Sweden)

    Alper Otunctemur

    2013-06-01

    Full Text Available Aim: Transrectal ultrasound (TRUS guided prostete biopsy is accepted as a standard procedure in the diagnosis of prostate cancer. Many different protocoles are applied to reduce the pain during the process. In this study we aimed to the comparison of two procedure with intrarectal lidocaine gel and periprostatice nerve blockade respective- ly in addition to perianal intrarectal lidocaine gel on the pain control in prostate biop- sy by TRUS. Methods: 473 patients who underwent prostate biopsy guided TRUS between 2008-2012 were included in the study. 10-point linear visual analog pain scale(VAS was used to evaluate the pain during biopsy. The patients were divided into two groups according to anesthesia procedure. In Group 1, there were 159 patients who had perianal-intrarectal lidocaine gel, in Group 2 there were 314 patients who had periprostatic nerve blockade in addition to intrarectal lidocain gel. The pain about probe manipulation was aseesed by VAS-1 and during the biopsy needle entries was evalu- ated by VAS-2. Results were compared with Mann-Whitney U and Pearson chi-square test. Results: Mean VAS-2 scores in Group 1 and Group 2 were 4.54 ± 1.02 and 2.06 ± 0.79 respectively. The pain score was determined significantly lower in the Group 2 (p = 0.001. In both groups there was no significant difference in VAS-1 scores, patient’s age, prostate volume, complication rate and PSA level. Conclusion: The combination of periprostatic nerve blockade and intrarectal lidocain gel provides a more meaningful pain relief compared to group of patients undergoing intrarectal lidocaine gel.

  7. Quality control in audit firm

    OpenAIRE

    Dostálová, Milena

    2008-01-01

    Thesis deals with the quality control of audit firms in accordance with international regulations. Defining the requirements for quality based on the Code of Ethics and the International quality standard ISQC1. Part of this work is the practical demonstration of ISQC1 in the smaller audit firm. For comparison, there is a description of quality control in the U.S.

  8. Effect of endometrial biopsy on intrauterine insemination outcome in controlled ovarian stimulation cycle

    Directory of Open Access Journals (Sweden)

    Leena Wadhwa

    2015-01-01

    Full Text Available OBJECTIVE: The objective was to evaluate the effect of endometrial biopsy (EB on intrauterine insemination (IUI outcome in controlled ovarian stimulation (COS cycle. DESIGN: Prospective randomized control study. SETTING: Tertiary care center. MATERIALS AND METHODS: A total of 251 subjects were enrolled in the study. Subjects undergoing COS with IUI were randomly allocated into three groups. Group A: EB was taken between D19 and 24 of the spontaneous menstrual cycles that precedes the fertility treatment and IUI, which was done in next cycle (n = 86. Group B: EB was taken before D6 of the menstrual cycle, and fertility treatment and IUI was done in the same cycle (n = 90. Group C: (control group no EB in previous 3 cycle (n = 75. MAIN OUTCOME MEASURE: Clinical pregnancy rate (CPR. RESULTS: Clinical pregnancy rate was 19.77%, 31.11%, and 9.3% for Group A, Group B, and Group C, respectively. The results show a highly significant value for the paired t-test of intervention Group B and control Group C of the cases (P = 0.000957. CPR was maximum afterfirst cycle of ovulation induction and IUI following EB scratch in both Groups A and in Group B (P < 0.001. CONCLUSIONS: Endometrial biopsy done in early follicular phase in the same cycle of stimulation with IUI gives better CPR as compared with EB done in the luteal phase of the previous cycle.

  9. Biopsy-controlled liver fibrosis staging using the enhanced liver fibrosis (ELF score compared to transient elastography.

    Directory of Open Access Journals (Sweden)

    Kristin Wahl

    Full Text Available BACKGROUND AND AIMS: Chronic liver diseases are characterized by inflammatory and fibrotic liver injuries that often result in liver cirrhosis with its associated complications such as portal hypertension and hepatocellular carcinoma. Liver biopsy still represents the reference standard for fibrosis staging, although transient elastography is increasingly used for non-invasive monitoring of fibrosis progression. However, this method is not generally available and is associated with technical limitations emphasizing the need for serological biomarkers staging of liver fibrosis. The enhanced liver fibrosis (ELF score was shown to accurately predict significant liver fibrosis in different liver diseases, although extracellular matrix components detected by this score may not only mirror the extent of liver fibrosis but also inflammatory processes. METHODS: In this prospective biopsy-controlled study we evaluated the utility of the ELF score in comparison to transient elastography to predict different stages of fibrosis in 102 patients with chronic liver diseases. RESULTS: Both techniques revealed similar area under receiver operating characteristic curve values for prediction of advanced fibrosis stages. Compared to transient elastography, the ELF score showed a broader overlap between low and moderate fibrosis stages and a stronger correlation with inflammatory liver injury. CONCLUSIONS: Both the ELF score as well as transient elastography allowed for high quality fibrosis staging. However, the ELF score was less discriminative in low and moderate fibrosis stages and appeared more strongly influenced by inflammatory liver injury. This should be considered when making clinical interpretations on the basis of ELF score values.

  10. Accuracy of Colposcopically Directed Biopsy: Results from an Online Quality Assurance Programme for Colposcopy in a Population-Based Cervical Screening Setting in Italy

    Directory of Open Access Journals (Sweden)

    Mario Sideri

    2015-01-01

    Full Text Available Purpose. To report the accuracy of colposcopically directed biopsy in an internet-based colposcopy quality assurance programme in northern Italy. Methods. A web application was made accessible on the website of the regional Administration. Fifty-nine colposcopists out of the registered 65 logged in, viewed a posted set of 50 digital colpophotographs, classified them for colposcopic impression and need for biopsy, and indicated the most appropriate site for biopsy with a left-button mouse click on the image. Results. Total biopsy failure rate, comprising both nonbiopsy and incorrect selection of biopsy site, was 0.20 in CIN1, 0.11 in CIN2, 0.09 in CIN3, and 0.02 in carcinoma. Errors in the selection of biopsy site were stable between 0.08 and 0.09 in the three grades of CIN while decreasing to 0.01 in carcinoma. In multivariate analysis, the risk of incorrect selection of biopsy site was 1.97 for CIN2, 2.52 for CIN3, and 0.29 for carcinoma versus CIN1. Conclusions. Although total biopsy failure rate decreased regularly with increasing severity of histological diagnosis, the rate of incorrect selection of biopsy site was stable up to CIN3. In multivariate analysis, CIN2 and CIN3 had an independently increased risk of incorrect selection of biopsy site.

  11. Biopsy - polyps

    Science.gov (United States)

    Polyp biopsy ... are treated is the colon. How a polyp biopsy is done depends on the location: Colonoscopy or flexible sigmoidoscopy explores the large bowel Colposcopy-directed biopsy examines the vagina and cervix Esophagogastroduodenoscopy (EGD) or ...

  12. Synovial biopsy

    Science.gov (United States)

    Biopsy - synovial membrane ... fluid in and out of the area. A biopsy grasper is inserted through the trocar and turned ... Synovial biopsy helps diagnose gout and bacterial infections, or rule out other infections. It can be used to diagnose ...

  13. Nerve biopsy

    Science.gov (United States)

    Biopsy - nerve ... A nerve biopsy is most often done on a nerve in the ankle, forearm, or along a rib. The health care ... feel a prick and a mild sting. The biopsy site may be sore for a few days ...

  14. Endometrial biopsy

    Science.gov (United States)

    Biopsy - endometrium ... The biopsy is normal if the cells in the sample are not abnormal. ... Risks of endometrial biopsy include: Infection Causing a hole in (perforating) the uterus or tearing the cervix (rarely occurs) Prolonged bleeding Slight spotting ...

  15. Liver biopsy

    Science.gov (United States)

    Biopsy - liver; Percutaneous biopsy ... the biopsy needle to be inserted into the liver. This is often done by using ultrasound. The ... the chance of damage to the lung or liver. The needle is removed quickly. Pressure will be ...

  16. Skin Biopsy

    Science.gov (United States)

    ... skin condition cannot be diagnosed by the patient's history and what the physician finds on examination alone. Confirming a clinical diagnosis may also be necessary prior to starting therapy. Skin biopsy types are as follows: Shave biopsies Punch biopsies ...

  17. SIMBAD quality-control

    Science.gov (United States)

    Lesteven, Soizick

    1992-01-01

    The astronomical database SIMBAD developed at the Centre de donnees astronomiques de Strasbourg presently contains 760,000 objects (stellar and non-stellar). It has the unique characteristic of being structured specifically for astronomical objects. All types of heterogeneous data (bibliographic references, measurements, and sets of identification) are connected with each object. The attributes that define quality of the database include the following. Reliability: cross-identification should not rely upon just exact values object coordinates. It also means that information attached to one simple object should be consistent. The existing data must be controlled in order to start with a reliable base and to cross-identify new data assuring the quality as data grows. Exhaustivity: delays between publication of new informations and their inclusion in the database should be as short as possible. The integrity of the database has to be maintained as data accumulates. Taking the amount of data into consideration and the rate of new data production, it is necessary to use automatic methods. One of the possibilities is to use multivariate data analysis. The factor-space is a n-dimensional relevancy space which is described by the n-axes representing a set of n subject matter headings; the words and phrases can be used to scale the axes and the documents are then a vector average of the terms within them. The application reported herein is based on the NASA-STI bibliographical database. The selected data concern astronomy, astrophysics, and space radiation (102,963 references from 1975 to 1991 included 8070 keywords). The F-space is built from this bibliographical data. By comparing the F-space position obtained from the NASA-STI keywords with the F-space position obtained from the SIMBAD references, the authors will be able to show whether it is possible to retrieve information with a restricted set of words only. If the comparison is valid, this will be a way to enter

  18. Ultrasound guided robotic biopsy using augmented reality and human-robot cooperative control.

    Science.gov (United States)

    Freschi, C; Troia, E; Ferrari, V; Megali, G; Pietrabissa, A; Mosca, F

    2009-01-01

    Ultrasound-guided biopsy is a proficient mininvasive approach for tumors staging but requires very long training and particular manual and 3D space perception abilities of the physician, for the planning of the needle trajectory and the execution of the procedure. In order to simplify this difficult task, we have developed an integrated system that provides the clinician two types of assistance: an augmented reality visualization allows accurate and easy planning of needle trajectory and target reaching verification; a robot arm with a six-degree-of-freedom force sensor allows the precise positioning of the needle holder and allows the clinician to adjust the planned trajectory (cooperative control) to overcome needle deflection and target motion. Preliminary tests have been executed on an ultrasound phantom showing high precision of the system in static conditions and the utility and usability of the cooperative control in simulated no-rigid conditions. PMID:19963882

  19. Quality control of radioisotopic products

    International Nuclear Information System (INIS)

    Radiopharmaceutical quality control is a very comprehensive and responsible activity since it concerns products being used for the health care of patients. Quality control is practised by an analytical specialist in close cooperation with pharmacists who are responsible for routine quality assurance. There is also a good understanding with the production group to ensure high-quality products. Quality control also relies on the research and development group to investigate problems. Finally there is feedback from the user since he is also responsible for quality control in a limited way. The scope of quality control is comprehensive, e.g. physical inspection and chemical control of all inactive starting material including supervision of the various stages of production. The quality control of radioactive material includes nuclidic analysis, verification of radiochemical purity as well as regular stability checks. Biological controls comprise sterility tests both on final products and production environment; testing for toxicity, pyrogens and LD50 values. To test product efficacy it is imperative to rely on biodistribution. Rabbits are used for quality control screening in a qualitative static mode and the dissection of mice organs is carried out for time-consuming quantitative analyses. Since radiopharmaceuticals are being used in a dynamic mode by nuclear medicine, their quality control tests on animals should, for proper evaluation, be carried out by means of comparative studies with imported products and by using a high-resolution camera with computer facilities. The Group for Quality Control and Assurance is responsible for an extensive documentation system which ensures both good manufacturing practice and effective analytical tests. Through quality control the specialist is constantly striving for improvement to ensure a good product for the benefit of the patient

  20. Quality assurance and statistical control

    DEFF Research Database (Denmark)

    Heydorn, K.

    In scientific research laboratories it is rarely possible to use quality assurance schemes, developed for large-scale analysis. Instead methods have been developed to control the quality of modest numbers of analytical results by relying on statistical control: Analysis of precision serves to...

  1. Process control of product quality.

    Science.gov (United States)

    Venkatesan, G

    2003-10-01

    This paper describes a method to control output product quality (product variability) by applying engineering or automatic process control (APC) and statistical process control (SPC) techniques. APC techniques have been used to control process variables such as feed rate, temperature, pressure, viscosity, and to product quality variables as well. SPC techniques have also been applied to control product quality. APC and SPC techniques overlap at the interface of the two process control methodologies. It is possible to produce material of desired quality by having an acceptable level of variation in the measured output characteristics. APC aims to maintain certain key process variables as near their set points for as much of the time as possible. There are situations in process control where some form of feedback control is necessary and yet where stability cannot be easily attained in the feedback control loop. Disturbance (noise) afflicts a process, which together with issues of dynamics and dead time (time delay) compounds the process control problem. The process control practitioner faces a challenge while tackling issues of process delay (dead time) and dynamics (inertia). Process control of product variability (control error standard deviation) is possible by developing and simulating a feedback control algorithm for dead-time processes. It is quite common to encounter problems connected with feedback (closed-loop) control stability, controller limitations, and dead-time compensation to obtain minimum variance (mean square error) control at the output. Details of a method to control the quality of a product at output by applying statistical process monitoring and feedback control adjustment are presented in this paper. The focus of this paper is on the issues of process delay ("dead time") and dynamics ("inertia") at the interface between SPC and APC to control output product quality. PMID:14582886

  2. Frontiers in statistical quality control

    CERN Document Server

    Wilrich, Peter-Theodor

    2004-01-01

    This volume treats the four main categories of Statistical Quality Control: General SQC Methodology, On-line Control including Sampling Inspection and Statistical Process Control, Off-line Control with Data Analysis and Experimental Design, and, fields related to Reliability. Experts with international reputation present their newest contributions.

  3. Quality assurance programme and quality control

    International Nuclear Information System (INIS)

    The paper analyses the requirements for the quality assurance and control in nuclear power plant projects which are needed to achieve safe, reliable and economic plants. The author describes the structure for the establishment of a nuclear programme at the national level and the participation of the different bodies involved in a nuclear power plant project. The paper ends with the study of a specific case in Spain. (NEA)

  4. Parathyroid biopsy

    Science.gov (United States)

    ... Feel The test feels like a quick needle jab or stick. You may feel a sting as ... activities the same day. Alternative Names Biopsy - parathyroid Images Endocrine glands Parathyroid biopsy References Pellitteri PK, Sofferman ...

  5. CA Water Quality Control Board

    Data.gov (United States)

    U.S. Environmental Protection Agency — Regional Water Quality Control Boards(9) in California. These district boundaries coincide with the boundaries of some of the hydrologic study areas delineated by...

  6. Quality control of labelled compounds

    International Nuclear Information System (INIS)

    Some advantages and disadvantages of methods used for quality control of organic labelled compounds (131I, 14C) are shortly discussed. The methods used are electrophoresis, ultraviolet and infrared spectrometry, radiogas and thin-layer chromatography. (author)

  7. Poor glycemic control of diabetes mellitus is associated with higher risk of prostate cancer detection in a biopsy population.

    Directory of Open Access Journals (Sweden)

    Juhyun Park

    Full Text Available To evaluate the impact of glycemic control of diabetes mellitus (DM on prostate cancer detection in a biopsy population.We retrospectively reviewed the records of 1,368 men who underwent prostate biopsy at our institution. We divided our biopsy population into three groups according to their history of DM, and their Hemoglobin A1c (HbA1c level: a no-DM (DM- group; a good glycemic control (DM+GC group (HbA1c <6.5%; and a poor glycemic control (DM+PC group (HbA1c ≥6.5%. For sub-analyses, the DM+PC group was divided into a moderately poor glycemic control (DM+mPC group (6.5≤ HbA1c <7.5% and a severely poor glycemic control (DM+sPC group (HbA1c ≥7.5%.Among 1,368 men, 338 (24.7% had a history of DM, and 393 (28.7% had a positive biopsy. There was a significant difference in prostatic specific antigen density (PSAD (P = 0.037 and the frequency of abnormal DRE findings (P = 0.031 among three groups. The occurrence rate of overall prostate cancer (P<0.001 and high-grade prostate cancer (P = 0.016 also presented with a significantly difference. In the multivariate analysis, the DM+PC group was significantly associated with a higher rate of overall prostate cancer detection in biopsy subjects compared to the DM- group (OR = 2.313, P = 0.001 but the DM+PC group was not associated with a higher rate of high-grade (Gleason score ≥7 diseases detected during the biopsy (OR = 1.297, P = 0.376. However, in subgroup analysis, DM+sPC group was significantly related to a higher risk of high-grade diseases compared to the DM- group (OR = 2.446, P = 0.048.Poor glycemic control of DM was associated with a higher risk of prostate cancer detection, including high-grade disease, in the biopsy population.

  8. SAQC: SNP Array Quality Control

    Directory of Open Access Journals (Sweden)

    Li Ling-Hui

    2011-04-01

    Full Text Available Abstract Background Genome-wide single-nucleotide polymorphism (SNP arrays containing hundreds of thousands of SNPs from the human genome have proven useful for studying important human genome questions. Data quality of SNP arrays plays a key role in the accuracy and precision of downstream data analyses. However, good indices for assessing data quality of SNP arrays have not yet been developed. Results We developed new quality indices to measure the quality of SNP arrays and/or DNA samples and investigated their statistical properties. The indices quantify a departure of estimated individual-level allele frequencies (AFs from expected frequencies via standardized distances. The proposed quality indices followed lognormal distributions in several large genomic studies that we empirically evaluated. AF reference data and quality index reference data for different SNP array platforms were established based on samples from various reference populations. Furthermore, a confidence interval method based on the underlying empirical distributions of quality indices was developed to identify poor-quality SNP arrays and/or DNA samples. Analyses of authentic biological data and simulated data show that this new method is sensitive and specific for the detection of poor-quality SNP arrays and/or DNA samples. Conclusions This study introduces new quality indices, establishes references for AFs and quality indices, and develops a detection method for poor-quality SNP arrays and/or DNA samples. We have developed a new computer program that utilizes these methods called SNP Array Quality Control (SAQC. SAQC software is written in R and R-GUI and was developed as a user-friendly tool for the visualization and evaluation of data quality of genome-wide SNP arrays. The program is available online (http://www.stat.sinica.edu.tw/hsinchou/genetics/quality/SAQC.htm.

  9. Prostate biopsy tracking with deformation estimation

    CERN Document Server

    Baumann, Michael; Daanen, Vincent; Troccaz, Jocelyne

    2011-01-01

    Transrectal biopsies under 2D ultrasound (US) control are the current clinical standard for prostate cancer diagnosis. The isoechogenic nature of prostate carcinoma makes it necessary to sample the gland systematically, resulting in a low sensitivity. Also, it is difficult for the clinician to follow the sampling protocol accurately under 2D US control and the exact anatomical location of the biopsy cores is unknown after the intervention. Tracking systems for prostate biopsies make it possible to generate biopsy distribution maps for intra- and post-interventional quality control and 3D visualisation of histological results for diagnosis and treatment planning. They can also guide the clinician toward non-ultrasound targets. In this paper, a volume-swept 3D US based tracking system for fast and accurate estimation of prostate tissue motion is proposed. The entirely image-based system solves the patient motion problem with an a priori model of rectal probe kinematics. Prostate deformations are estimated with ...

  10. 10 CFR 26.137 - Quality assurance and quality control.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Quality assurance and quality control. 26.137 Section 26....137 Quality assurance and quality control. (a) Quality assurance program. Each licensee testing facility shall have a quality assurance program that encompasses all aspects of the testing...

  11. 10 CFR 26.167 - Quality assurance and quality control.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Quality assurance and quality control. 26.167 Section 26... Department of Health and Human Services § 26.167 Quality assurance and quality control. (a) Quality assurance program. Each HHS-certified laboratory shall have a quality assurance program that encompasses all...

  12. TRANSRECTAL ULTRASOUND GUIDED PROSTATIC NERVE BLOCKADE FOR PAIN CONTROL DURING TRANSRECTAL PROSTATE BIOPSY

    Institute of Scientific and Technical Information of China (English)

    YANG Liu-ping; DENG Jun-hong; ZHONG Hong; HU Jian-bo; WEI Hong-ai; WANG Liang-sheng

    2005-01-01

    Objective: To assess the effect of transrectal ultrasound guided prostatic nerve blockade on the discomfort associated with systematic biopsy of the prostate. Methods: 73 patients receiving systematic 13 cores biopsy of the prostate were randomized into two groups. Group A(37 cases) received an injection of 5 ml 1% lidocaine into the prostatic neurovascular bundles on each side at the base of the prostate under ultrasound guidance and group B(36 cases) received 5 ml saline injection (0.9% sodium chloride) at the same site. Pain during biopsy was assessed by using a 10-point linear visual analog score (VAS) immediately after the biopsy. Results: The mean pain scores during transrectal prostate biopsy were significantly lower in group A than group B(1.1±0.6 versus 5.9±3.1, t=4.81, P<0.01). During this study no patient in either group had any adverse effect from the injection. Conclusion: Transcrectal ultrasound guided prostatic nerve blockade is a safe and efficacious method for providing satisfactory anesthesia in transrectal prostate biopsy. We recommend its routine administration in all patients during this procedure.

  13. Comparison of diagnostic quality of kidney biopsy obtained using 16g and 18g needles in patients with diffuse renal disease

    Directory of Open Access Journals (Sweden)

    Komal Arora

    2012-01-01

    Full Text Available To determine the diagnostic quality and complication rates of 16G and 18G needles in biopsy of the kidney, we performed renal biopsy using a biopsy gun under ultrasound guidance in 50 patients who were prospectively and evenly assigned to one of the two needle biopsy methods from April 2007 until May 2008. Two cores of renal biopsy specimen were obtained in each case and subjected to histopathological and immunoflourescence (IF examination. Pain associated with the procedure was assessed using a visual analog scale. The number of glomeruli retrieved using the 16G needle ranged from 0 to 30 (mean 9.42 ± 5.5 and those retrieved using 18G needle ranged from 0 to 19 (mean 7.72 ± 4.4, P <0.05. The quality of biopsy was poorer with 18G needle as compared with 16G needles because of a higher amount of fragmentation and crushing artifact. There was no difference in the compli-cation rates between the two needles (2% each. The 16G needle was associated with significantly more pain than the 18G needle. We conclude that our study demonstrates the benefit of the larger 16G needle in providing more tissue and glomeruli, which is more diagnostically useful. However, the use of 16G needle was associated with significantly more pain than the 18G needle, and may be a better compromise for diagnostic usefulness and patient acceptability.

  14. Essential elements of quality control.

    Science.gov (United States)

    Boylan, J C

    1983-11-01

    The components of quality control in the pharmaceutical industry are discussed as they apply to hospital pharmacy admixture services. The pharmaceutical industry complies with the FDA's Current Good Manufacturing Practices, which require manufacturers to have written procedures for ensuring sterility and nonpyrogenicity of injectable products. Because FDA specifies only what outcome measures must be assessed (rather than specific means of assessment), pharmaceutical companies have developed a multiplicity of quality-control systems. However, each system consists of a master formula (quantitative listing of all ingredients), master manufacturing instructions (the recipe for each product), master packaging instructions, and batch records. Documents used by quality control personnel include the specifications (identification, tests, and limits for products), test methods, and sampling procedures. Hospitals should have similar quality-control programs. These programs should systematically prevent or identify and correct deficiencies, measure overall quality, and provide information for managers. Hospital pharmacists whose departments do not have comprehensive programs should consult colleagues who have developed such procedures. Techniques used in industry should be applied when possible. To protect the integrity of manufacturers' drug products during compounding in hospitals, every hospital admixture service must have its own quality-control system. PMID:6650523

  15. The biopsy of the boar testes using ultrasonographic examination

    Directory of Open Access Journals (Sweden)

    Laima Liepa

    2014-03-01

    Full Text Available The biopsy of live animal testes is an important clinical manipulation to control spermatogenesis and reproductive system pathologies. The aim was to develop a method of boar testes biopsy using a biopsy gun with ultrasound guidance and to investigate the influence of this procedure on the boar testes parenchyma and quality of ejaculate. The biopsy was carried out in six 8-month-old boars. Fourteen days prior to and 21 days after biopsy, the quality of ejaculate was examined (weight of ejaculate; concentration and motility of spermatozoa with a seven-day intervals. Ultrasound images of the testes parenchyma were recorded three times: directly before and 15 minutes after the biopsy, then 21 days after the procedure. The testes biopsies of generally anesthetized boars were performed with the biopsy gun for needle biopsy with a 12cm long, disposable 16-gauge needle 1.8mm in diameter (Vitesse through 1cm skin incision in the depth of 1.2-1.6cm of parenchyma. Fifteen minutes after the biopsy, macroscopic injures of the parenchyma of all the boar testes were not detected in the ultrasound image. Twenty one days after biopsy, the hyperechogenic line 0.1-0.2cm in diameter was seen in the testes parenchyma of six boars in the depth of 1.2-1.6cm. The biopsy of boar testes did not influence the quality of boars ejaculate. The ultrasonographic examination of boar testicles before the biopsy reduced possibilities to traumatize large blood vessels of the testes. A perfect boar testicular biopsy was easy to perform using ultrasonographic examination in the pigsty conditions.

  16. Frontiers in statistical quality control

    CERN Document Server

    Wilrich, Peter-Theodor

    2001-01-01

    The book is a collection of papers presented at the 5th International Workshop on Intelligent Statistical Quality Control in Würzburg, Germany. Contributions deal with methodology and successful industrial applications. They can be grouped in four catagories: Sampling Inspection, Statistical Process Control, Data Analysis and Process Capability Studies and Experimental Design.

  17. Quality assurance and statistical control

    DEFF Research Database (Denmark)

    Heydorn, K.

    1991-01-01

    In scientific research laboratories it is rarely possible to use quality assurance schemes, developed for large-scale analysis. Instead methods have been developed to control the quality of modest numbers of analytical results by relying on statistical control: Analysis of precision serves to...... through the origo. Calibration control is an essential link in the traceability of results. Only one or two samples of pure solid or aqueous standards with accurately known content need to be analyzed. Verification is carried out by analyzing certified reference materials from BCR, NIST, or others; their...

  18. Estrogen and progesterone receptor levels in nonneoplastic breast epithelium of breast cancer cases versus benign breast biopsy controls

    International Nuclear Information System (INIS)

    Previous studies and biological mechanisms of carcinogenesis suggest that the steroid receptor content of benign breast epithelium may be related to breast cancer risk. The objective in this study was to compare the levels of estrogen receptor-α (ER) and progesterone receptor (PR) in nonneoplastic breast epithelium between breast cancer cases and biopsy controls. Between 1995 and 1997 at two sites (Women's College Hospital in Toronto and Kingston General Hospital), 667 women who were scheduled for diagnostic excisional breast biopsies completed a questionnaire providing personal information and agreed to allow analysis of routinely resected tissue. Histological slides with nonneoplastic epithelium were available for 101 cancer cases and 200 biopsy controls in Toronto and for 105 cancer cases and 119 controls in Kingston. Nonneoplastic epithelium was examined with immunohistochemical assays to determine the percent of epithelial cells staining for ER and PR. Unconditional logistic regression was used to calculate odds ratios (OR) stratified by study site. The ER content of nonneoplastic tissue was higher in cases than biopsy controls in unadjusted analyses; after adjustment for age, however, a weak association remained in only one of the study sites. After adjustment for age, the PR content of nonneoplastic tissue was slightly lower in breast cancer cases than controls in one study site. Furthermore, this inverse association was confined to women with PR negative breast cancer in comparison to the controls. No interaction between ER and PR content of nonneoplastic tissue was observed in relation to the odds of having breast cancer. The results of this study are consistent with only a slight indication of increased ER levels in nonneoplastic tissue in breast cancer cases relative to controls. This study contributes to the understanding of breast cancer by examining both ER and PR in nonneoplastic tissue. Limitations remain, however, such as the necessity of

  19. Quality assurance, quality control and quality audit in diagnostic radiology

    International Nuclear Information System (INIS)

    Full text:The lecture aims to present contemporary view of quality assurance in X-Ray diagnosis and its practical realization in Bulgaria. In the lecture the concepts of quality assurance, quality control and clinical audit will be defined and their scope will be considered. An answer of the following questions will be given: why is it necessary to determine the dose of patient in X-ray studies, what is the reference dose level and how it is used for dosimetric quantity which characterized the patient's exposure in X-ray, mammography and CT scans and how they are measured, who conducted the measurement and how to keep the records, what are the variations of doses in identical tests and what defines them? The findings from a national survey of doses in diagnostic radiology, conducted in 2008-2009 and the developed new national reference levels will be presented. The main findings of the first tests of radiological equipment and the future role of quality control as well as the concept of conducting clinical audit and its role in quality assurance are also presented. Quality assurance of the diagnostic process with minimal exposure of patients is a strategic goal whose realization requires understanding, organization and practical action, both nationally and in every hospital. To achieve this the important role of education and training of physicians, radiological technicians and medical physicists is enhanced

  20. Post-mortem tissue biopsies obtained at minimally invasive autopsy: an RNA-quality analysis.

    Directory of Open Access Journals (Sweden)

    Anita van der Linden

    Full Text Available Bereaved relatives often refuse to give consent for post-mortem investigation of deceased cancer patients, mainly because of the mutilation due to conventional autopsy (CA. Minimally invasive autopsy (MIA may be a more acceptable alternative and, if implemented in clinical practice, creates an opportunity to more often obtain post-mortem tissue samples of (recurred primary tumors and metastases for molecular research. As a measure for tissue quality for molecular studies, we hereby present a feasibility study, comparing the RNA quality of MIA and CA samples, and fresh frozen samples as reference.Tissue samples of heart, liver and kidney were prospectively collected from 24 MIAs followed by CA, and compared to corresponding archival fresh frozen tissue. After RNA isolation and RT-qPCR, RNA integrity numbers (RIN and GAPDH expression (six amplicon sizes ranging from 71 to 530 base pairs were measured. RIN values and GAPDH Cq values were analyzed and compared between all sample groups and post-mortem intervals (PMI.RIN values in MIA samples were significantly higher than those in CA samples. GAPDH was expressed significantly higher in MIA samples than in CA samples and 530 bp PCR products could be measured in all cases. GAPDH expression was significantly lower in samples with PMI >15 hours. As expected, the samples of the fresh frozen reference standard performed best in all analyses.MIA samples showed better RNA quality than CA samples, probably due to shorter PMI. Both had lower RNA quality and expression levels than fresh frozen tissue, however, remaining GAPDH RNA was still sufficiently intact. Therefore, other highly expressed genes are most likely also detectable. Gene array analysis should be performed to gain insight into the quality of entire post-mortem genomes. Reducing PMI will further improve the feasibility of demanding molecular research on post-mortem tissues, this is most likely more feasible with MIA than CA.

  1. [Color Doppler controlled needle biopsy in diagnosis of soft tissue and bone tumors].

    Science.gov (United States)

    Schulte, M; Heymer, B; Sarkar, M R; Negri, G; von Baer, A; Hartwig, E

    1998-10-01

    In a prospective study we investigated 168 patients with musculoskeletal tumors, including 71 sarcomas, by core needle biopsy using the high-speed device Autovac. Monitoring with colour-coded duplex sonography allowed a well-aimed puncture of smaller or deeply localized lesions and also permitted the discrimination of necrotic and viable parts of the tumor. Adequate material for histologic diagnosis including grading and determination of tumor subtype was obtained from soft tissue sarcomas, soft tissue metastases, malignant lymphomas, plasmacytomas, and osteolytic skeletal secondaries. In contrast, in benign soft tissue and bone tumors the diagnosis could be established in only 66% of cases. Although skeletal sarcomas were identified as malignant mesenchymal lesions, a complete histologic classification of tumor subtype frequently was not possible due to an insufficient tissue specimen. With an accuracy of 97% for the diagnosis of malignancy and of 94% for the diagnosis of soft tissue sarcoma the results of core needle biopsies were comparable to those of incisional biopsies, the reference standard in the diagnosis of musculoskeletal tumors. Regarding the known disadvantages and the oncological risks of incisional biopsies, needle biopsy should replace the open procedure as the primary means of diagnosis in soft tissue and osteolytic bone tumors. PMID:9833186

  2. Quality control without a budget

    International Nuclear Information System (INIS)

    This paper has been prepared to provide assistance to those radiographers wishing to undertake equipment quality control in the Radiology Department where funding for this function is minimal or non-existent. Successful quality assurance means the ability to maximize the use of the radiation dose to patients and simultaneously reduce staff dose; plus maximize cost savings through improved patient throughput, reduced wastage of resources such as film, chemistry and staff time. 10 refs., 6 figs

  3. Quality control of imaging devices

    International Nuclear Information System (INIS)

    Quality assurance in nuclear medicine refers collectively to all aspects of a nuclear medicine service. It would include patient scheduling, radiopharmaceutical preparation and dispensing, radiation protection of patients, staff and general public, preventive maintenance and the care of instruments, methodology, data interpretation and records keeping, and many other small things which contribute directly or indirectly to the overall quality of a nuclear medicine service in a hospital. Quality Control, on the other hand, refers to a signal component of the system and is usually applied in relation to a specific instrument and its performance

  4. Quality control for dose calibrators

    International Nuclear Information System (INIS)

    Nuclear medicine laboratories are required to assay samples of radioactivity to be administered to patients. Almost universally, these assays are accomplished by use of a well ionization chamber isotope calibrator. The Instituto de Radioprotecao e Dosimetria (Institute for Radiological Protection and Dosimetry) of the Comissao Nacional de Energia Nuclear (National Commission for Nuclear Energy) is carrying out a National Quality Control Programme in Nuclear Medicine, supported by the International Atomic Energy Agency. The assessment of the current needs and practices of quality control in the entire country of Brazil includes Dose Calibrators and Scintillation Cameras, but this manual is restricted to the former. Quality Control Procedures for these Instruments are described in this document together with specific recommendations and assessment of its accuracy. (author)

  5. Radiation measurements and quality control

    International Nuclear Information System (INIS)

    The association between radiation measurements and quality control is established for radiation sterilization of medical products and food irradiation. Good quality control implies accurate radiation dosimetry and a discussion of the factors which can affect the accuracy of in-plant dosimetry is presented. It is argued that if systematic errors are to be avoided in in-plant dosimetry the plant operators will have to spend more time and effort in developing the skills associated with the accurate use of radiation dosemeter systems. The aims and merits of an international intercomparison programme recently set up by the IAEA are discussed. The benefits of accurate in-plant dosimetry for the operator, approving authority and purchaser are balanced against the extra dosimetric efforts required for good quality control. (author)

  6. 40 CFR 51.359 - Quality control.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Quality control. 51.359 Section 51.359....359 Quality control. Quality control measures shall insure that emission testing equipment is... quality control frequencies by using statistical process control to monitor equipment performance on...

  7. Regional distribution and alterations of lectin binding to colorectal mucin in mucosal biopsies from controls and subjects with inflammatory bowel diseases.

    OpenAIRE

    Jacobs, L R; Huber, P W

    1985-01-01

    Glycoconjugate composition of colorectal goblet cell mucin was characterized according to the anatomical distribution of lectin-binding sites in mucosal biopsies from 35 control subjects and 55 patients with inflammatory bowel disease. 24 of the controls had mucosal inflammation on biopsy, without clinical evidence of inflammatory bowel disease. These inflamed controls showed a similar rate of presence of lectin-binding sites as the normal noninflamed group. In the controls, the frequency of ...

  8. The OnControl bone marrow biopsy technique is superior to the standard manual technique for hematologists-in-training: a prospective, randomized comparison

    Directory of Open Access Journals (Sweden)

    Louis Juden Reed

    2011-10-01

    Full Text Available The purpose of this study was to compare a novel bone marrow device with the standard marrow needle in a prospective, randomized study in a teaching hospital employing hematologists- in-training. The new device, the OnControl Bone Marrow (OBM Biopsy System, utilizes a battery-powered drill to insert the needle. Fifty-four bone marrows (27 standard and 27 OBM were performed by 11 fellows under the observation and supervision of 3 attending hematologists and 1 research technologist. The primary endpoint of the study, the mean length of the marrow biopsy specimens, a surrogate for marrow quality, was determined by a pathologist in a blinded manner. The mean length of the marrow biopsy specimens was significantly longer (56% for the OBM group (15.3 mm than for the standard bone marrow (SBM group (9.8 mm, P<0.003. An objectively determined secondary endpoint; mean procedure time, skin-to-skin; also favored the OBM group (175 s versus the SBM group (292 s, P<0.007. Several subjective secondary endpoints also favored the OBM group. Only minor adverse events were encountered in the OBM and SBM study groups. It was concluded that bone marrow procedures (BMPs performed by hematologists- in-training were significantly faster and superior in quality when performed with the OBM compared to the SBM. These data suggest that the OBM may be considered a new standard of care for adult hematology patients. OBM also appears to be a superior method for training hematology fellows.

  9. Radiographic quality: Control and evaluation

    International Nuclear Information System (INIS)

    The control and evaluation of radiographic quality vary considerably from institution to institution, and this has resulted in increased government legislation in most jurisdictions, which attempts to provide some measure of uniformity in standards of equipment installation, maintenance, and use. Where legislation is not yet in place, it is pending, so that all facilities using x-radiation are, or soon will be, legally bound to operate within accepted guidelines. These guidelines are established to provide the radiologist with radiographs of optimum diagnostic quality while keeping the radiation dose to the patient and radiology personnel as low as possible. There are many excellent publications that provide detailed step-by-step instructions on each facet of radiographic quality control; these procedures will, therefore, not be covered in detail here. The following information may, however, be of interest as it relates primarily to pediatric radiography and will prove useful to those initiating quality control and evaluation programs; it is important that priorities be established - the necessary steps are listed below

  10. Quality control of EUVE databases

    Science.gov (United States)

    John, L. M.; Drake, J.

    1992-01-01

    The publicly accessible databases for the Extreme Ultraviolet Explorer include: the EUVE Archive mailserver; the CEA ftp site; the EUVE Guest Observer Mailserver; and the Astronomical Data System node. The EUVE Performance Assurance team is responsible for verifying that these public EUVE databases are working properly, and that the public availability of EUVE data contained therein does not infringe any data rights which may have been assigned. In this poster, we describe the Quality Assurance (QA) procedures we have developed from the approach of QA as a service organization, thus reflecting the overall EUVE philosophy of Quality Assurance integrated into normal operating procedures, rather than imposed as an external, post facto, control mechanism.

  11. Quality Assurance/Quality Control Jobs

    Science.gov (United States)

    Fanslau, Melody; Young, Janelle

    The production of a quality and safe food product is essential to the success of any food manufacturing facility. Because of this great importance, a career in quality can be extremely rewarding. Without happy customers willing to buy a product, a company would not be able to survive. Quality issues such as foreign objects, spoiled or mislabeled product, failure to meet net weight requirements, or a recall can all turn customers away from buying a product. The food industry is a customer-driven market in which some consumers are brand loyal based on a history of high quality or in which a single bad experience with a product will turn them away for a lifetime. With this said, the main role of a quality department is to help ensure that quality issues such as these are eliminated or kept to a minimum to maintain or increase the number of customers purchasing their product.

  12. Randomized controlled trial of antibiotic prophylaxis regimens for transrectai ultrasound-guided prostate biopsy

    Institute of Scientific and Technical Information of China (English)

    CHAN Eddie Shu-yin; LO Ka-lun; NG Chi-fai; HOU See-ming; YIP Sidney Kam-hung

    2012-01-01

    Background A prior study showed significant antibioti resistance to quinotone in our poputation.In this study we aimed to evaluate and compare the efficacy of a single versus a combined prophylactic antibiotic regimen before transrectal ultrasound-guided prostate biopsy(TRUGPB).Methods A prospective randomized study was conducted at a university hospital.Patients undergoing TRUGPB were randomized into an amoicillin-clavulanate alone(1mg;one dose before and two doses after biopsy)or an amoxicllin-clavulanate+ciprofloxacin group(250mg;one dose before and two doses after biopsy).Patients were surveyed for infection symptoms by phine on days 3 and 30 after TRUGPB.We defined an infective complication as the iccurrence of symptoms including fever,chills or rigor within 30 days after prostate biopsy,requiring medical treatment or hospitalization,aided by a tertiory-wide etectronic medical record system.Results Between November 2007 and July 2009,367 patients were randomized to either amoxicillin-clavulanate alone or amoxicillin-caavulanate+ciprofloxacin group.The infection rates after TRUGPB were 3.9%in the former group(7 out of 179 patoents)versus 0.53%(1 out of 188 patients)in the latter.Sixty-three percent(5/8)of patients with infective complications needed hospitalization.There was no intensive care unit admission or mortality during the study period.Conclusions Combining prophylactic antibiotics with amoxicllin-clavulanate+soprofloxacin significantly reduced the in cidence of infective complications after TRUGPB.We recommended a combination regimen,especially in centre with high incidence of post-TRUGPB infection.

  13. Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies.

    Science.gov (United States)

    Houghton, Jeffrey; Hadd, Andrew G; Zeigler, Robert; Haynes, Brian C; Latham, Gary J

    2016-01-01

    All next-generation sequencing (NGS) procedures include assays performed at the laboratory bench ("wet bench") and data analyses conducted using bioinformatics pipelines ("dry bench"). Both elements are essential to produce accurate and reliable results, which are particularly critical for clinical laboratories. Targeted NGS technologies have increasingly found favor in oncology applications to help advance precision medicine objectives, yet the methods often involve disconnected and variable wet and dry bench workflows and uncoordinated reagent sets. In this report, we describe a method for sequencing challenging cancer specimens with a 21-gene panel as an example of a comprehensive targeted NGS system. The system integrates functional DNA quantification and qualification, single-tube multiplexed PCR enrichment, and library purification and normalization using analytically-verified, single-source reagents with a standalone bioinformatics suite. As a result, accurate variant calls from low-quality and low-quantity formalin-fixed, paraffin-embedded (FFPE) and fine-needle aspiration (FNA) tumor biopsies can be achieved. The method can routinely assess cancer-associated variants from an input of 400 amplifiable DNA copies, and is modular in design to accommodate new gene content. Two different types of analytically-defined controls provide quality assurance and help safeguard call accuracy with clinically-relevant samples. A flexible "tag" PCR step embeds platform-specific adaptors and index codes to allow sample barcoding and compatibility with common benchtop NGS instruments. Importantly, the protocol is streamlined and can produce 24 sequence-ready libraries in a single day. Finally, the approach links wet and dry bench processes by incorporating pre-analytical sample quality control results directly into the variant calling algorithms to improve mutation detection accuracy and differentiate false-negative and indeterminate calls. This targeted NGS method uses

  14. Control of quality in mammography

    International Nuclear Information System (INIS)

    The present protocol of quality control/quality assurance in mammography is the result of the work of two regional projects realised in Latin America within the frame of ARCAL with the support of the IAEA. The first is ARCAL LV (RLA/6/043) project on quality assurance/quality control in mammography studies which analysed the present situation of the mammography in the member countries of the project which include: Bolivia, Colombia, Costa Rica, Cuba, El Salvador, Guatemala, Nicaragua, Panama, Paraguay, Peru, Dominican Republic and Republic of Venezuela and the second is ARCAL XLIX (RLA/9/035) project, whose members were Brazil, Colombia, Cuba, Chile, Mexico, and Peru, worked the application of Basic Safety Standards for the protection against ionising radiation with the aim to improve radiation protection in X-ray diagnosis medical practices through the implementation of the Basic Safety Standards (BSS) related to x-ray diagnosis in selected hospitals located in each country involved in the project. The work of both projects had been consolidated and harmonized in the present publication

  15. CRANE WHEELS PRODUCTION QUALITY CONTROL

    OpenAIRE

    OTTO GRIGOROV; SERHY GUBSKIY; ANTON OKUN

    2014-01-01

    Quality control of crane wheels is an important part for support of crane mechanisms permanent operation. Normal functioning of logistics systems requires preventing of crane downtimes and delays. The research results of the impact of the crane wheels (710 mm diameter, 65 steel) surface hardness on coercivity indicators are presented in this paper. Obtained research results of dependence between the coercivity indicators and the crane wheels rolling surface hardness for their use in practice ...

  16. Quality Control of Meteorological Observations

    Science.gov (United States)

    Collins, William; Dee, Dick; Rukhovets, Leonid

    1999-01-01

    For the first time, a problem of the meteorological observation quality control (QC) was formulated by L.S. Gandin at the Main Geophysical Observatory in the 70's. Later in 1988 L.S. Gandin began adapting his ideas in complex quality control (CQC) to the operational environment at the National Centers for Environmental Prediction. The CQC was first applied by L.S.Gandin and his colleagues to detection and correction of errors in rawinsonde heights and temperatures using a complex of hydrostatic residuals.Later, a full complex of residuals, vertical and horizontal optimal interpolations and baseline checks were added for the checking and correction of a wide range of meteorological variables. some other of Gandin's ideas were applied and substantially developed at other meteorological centers. A new statistical QC was recently implemented in the Goddard Data Assimilation System. The central component of any quality control is a buddy check which is a test of individual suspect observations against available nearby non-suspect observations. A novel feature of this test is that the error variances which are used for QC decision are re-estimated on-line. As a result, the allowed tolerances for suspect observations can depend on local atmospheric conditions. The system is then better able to accept extreme values observed in deep cyclones, jet streams and so on. The basic statements of this adaptive buddy check are described. Some results of the on-line QC including moisture QC are presented.

  17. Radiation measurements and quality control

    International Nuclear Information System (INIS)

    Accurate measurements are essential to research leading to a successful radiation process and to the commissioning of the process and the facility. On the other hand, once the process is in production, the importance to quality control of measuring radiation quantities (i.e., absorbed dose, dose rate, dose distribution) rather than various other parameters of the process (i.e. conveyor speed, dwell time, radiation field characteristics, product dimensions) is not clearly established. When the safety of the product is determined by the magnitude of the administered dose, as in radiation sterilization, waste control, or food preservation, accuracy and precision of the measurement of the effective dose are vital. Since physical dose measurements are usually simpler, more reliable and reproducible than biological testing of the product, there is a trend toward using standardized dosimetry for quality control of some processes. In many industrial products, however, such as vulcanized rubber, textiles, plastics, coatings, films, wire and cable, the effective dose can be controlled satisfactorily by controlling process variables or by product testing itself. In the measurement of radiation dose profiles by dosimetry, it is necessary to have suitable dose meter calibrations, to account for sources of error and imprecision, and to use correct statistical procedures in specifying dwell times or conveyor speeds and source and product parameters to achieve minimum and maximum doses within specifications. (author)

  18. 7 CFR 981.42 - Quality control.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Quality control. 981.42 Section 981.42 Agriculture... Regulating Handling Quality Control § 981.42 Quality control. (a) Incoming. Except as provided in this... establish, with the approval of the Secretary, such minimum quality and inspection requirements...

  19. 7 CFR 930.44 - Quality control.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Quality control. 930.44 Section 930.44 Agriculture... MICHIGAN, NEW YORK, PENNSYLVANIA, OREGON, UTAH, WASHINGTON, AND WISCONSIN Order Regulating Handling Quality Control § 930.44 Quality control. (a) Quality standards. The Board may establish, with the approval of...

  20. Renal Tumor Biopsy Technique

    Institute of Scientific and Technical Information of China (English)

    Lei Zhang; Xue-Song Li; Li-Qun Zhou

    2016-01-01

    Objective:To review hot issues and future direction of renal tumor biopsy (RTB) technique.Data Sources:The literature concerning or including RTB technique in English was collected from PubMed published from 1990 to 2015.Study Selection:We included all the relevant articles on RTB technique in English,with no limitation of study design.Results:Computed tomography and ultrasound were usually used for guiding RTB with respective advantages.Core biopsy is more preferred over fine needle aspiration because of superior accuracy.A minimum of two good-quality cores for a single renal tumor is generally accepted.The use of coaxial guide is recommended.For biopsy location,sampling different regions including central and peripheral biopsies are recommended.Conclusion:In spite of some limitations,RTB technique is relatively mature to help optimize the treatment of renal tumors.

  1. Quality control programme for radiotherapy

    International Nuclear Information System (INIS)

    A 3 years pilot programme started in January 2000 with 33 philanthropic cancer institutions that provides medical services to 60% of the patients from the national social security system. Brazil has today 161 radiotherapy services (144 operating with megavoltage equipment). These 33 institutions are distributed over 19 Brazilian states. The aim of this programme is: To create conditions to allow the participants to apply the radiotherapy with quality and efficacy; To promote up dating courses for the physicians, physicists and technicians of these 33 Institutions. With the following objectives: To recommend dosimetric and radiological protection procedures in order to guarantee the tumor prescribed dose and safe working conditions; To help in establishing and implementing these procedures. The main activities are: local quality control evaluations, postal TLD audits in reference conditions, postal TLD audits in off axis conditions and training. The local quality control program has already evaluated 22 institutions with 43 machines (25 Co-60 and 18 linear accelerators). In these visits we perform dosimetric, electrical, mechanical and safety tests. As foreseen, we found more problems among the old Co-60 machines i.e., field flatness, size, symmetry and relative output factors; lasers positioning system alignment; optical distance indicator; radiation and light field coincidence; optical and mechanical distance indicators agreement, than among the linear accelerators i.e., field flatness and size; lasers positioning system alignment; tray interlocking and wedge filter factors

  2. Quality control of pesticide products

    International Nuclear Information System (INIS)

    In light of an established need for more efficient analytical procedures, this publication, which documents the findings of an IAEA coordinated research project (CRP) on “Quality Control of Pesticide Products”, simplifies the existing protocol for pesticide analysis while simultaneously upholding existing standards of quality. This publication includes both a report on the development work done in the CRP and a training manual for use by pesticide analysis laboratories. Based on peer reviewed and internationally recognized methods published by the Association of Analytical Communities (AOAC) and the Collaborative International Pesticides Analytical Council (CIPAC), this report provides laboratories with versatile tools to enhance the analysis of pesticide chemicals and to extend the scope of available analytical repertoires. Adoption of the proposed analytical methodologies promises to reduce laboratories’ use of solvents and the time spent on reconfiguration and set-up of analytical equipment

  3. Family Control and Earnings Quality

    Directory of Open Access Journals (Sweden)

    Carolina Bona Sánchez

    2007-06-01

    Full Text Available El trabajo analiza la relación entre el control familiar y la calidad de la información contable en un contexto en el que el tradicional conflicto de agencia entre directivos y accionistas se desplaza a la divergencia de intereses entre accionistas controladores y minoritarios. Los resultados alcanzados muestran que, en comparación con las no familiares, las empresas de naturaleza familiar divulgan unos resultados de mayor calidad, tanto en términos de menores ajustes por devengo discrecionales como de mayor capacidad de los componentes actuales del resultado para predecir los cash flows futuros. Además, el aumento en los derechos de voto en manos de la familia controladora incrementa la calidad de los resultados contables. La evidencia obtenida se muestra consistente con la presencia de un efecto reputación/vinculación a largo plazo asociado a la empresa familiar. Adicionalmente, el trabajo refleja que a medida que disminuye la divergencia entre los derechos de voto y de cash flow en manos de la familia controladora, aumenta la calidad de la información contable.PALABRAS CLAVE: derechos de voto, divergencia, empresa familiar, calidad delresultado, reputación, beneficios privados.This work examines the relationship between family control and earnings quality in a context where the salient agency problem shifts away from the classical divergence between managers and shareholders to conflicts between the controlling owner and minority shareholders. The results reveal that, compared to non-family firms, family firms reveal higher earnings quality in terms of both lower discretionary accruals and greater predictability of future cash flows. They also show a positive relationship between the level of voting rights held by the controlling family and earnings quality. The evidence is consistent with the presence of a reputation/long-term involvement effect associated with the family firm. Moreover, the work reflects that, as the divergence

  4. Quality control in breast tomosynthesis

    Energy Technology Data Exchange (ETDEWEB)

    Jakubiak, R.R.; Messias, P.C.; Santos, M.F., E-mail: requi@utfpr.edu.br [Universidade Tecnologia Federal do Parana (UTFPR), Curitiba, PR (Brazil). Departamento Academico de Fisica; Urban, L.A.B.D., E-mail: lineiurban@hotmail.com [Diagnostico Avancado por Imagem, Curitiba, PR (Brazil)

    2015-07-01

    In Brazil, breast cancer is the most common and the leading cause of death among women, with estimated 57,000 new cases in 2014. The mammography (2D) plays an important role in the early detection of breast cancer, but in some cases can be difficult to detect malignant lesions due overlap of breast tissues. The Digital Breasts Tomosynthesis (DBT: 3D) reduces the effects of overlap, providing improved characterization of mammographic findings. However, the dose may double as compared with mammography. This study presents results of Contrast to Noise Ratio (CNR) and image quality evaluation on Siemens mammography equipment Mammomat Inspiration with tomosynthesis. The CNR was determined with Polymethylmethacrylate (PMMA) layers of 20 to 70 mm thick and an aluminum foils of 0,2 mm thickness and area of 10 mm². Image quality was assessed with the ACR Breast Simulator. In the evaluation of image quality, the detectability of fibers and masses was identical in 2D and 3D systems. Displaying fibers were 4,5 and 4 mass in both modes. In 2D mode were identified 3,5 microcalcifications groups, and 3D showed 3 groups. The Mean Glandular Dose (MGD) for the simulator in 2D mode was 1,17 mGy and 2,35 mGy for the 3D mode. The result reinforces the importance of quality control in the process of obtaining the images and obtained in accordance CNR values, ensuring image quality and compatible dose in 2D and 3D processes. (author)

  5. Quality control in breast tomosynthesis

    International Nuclear Information System (INIS)

    In Brazil, breast cancer is the most common and the leading cause of death among women, with estimated 57,000 new cases in 2014. The mammography (2D) plays an important role in the early detection of breast cancer, but in some cases can be difficult to detect malignant lesions due overlap of breast tissues. The Digital Breasts Tomosynthesis (DBT: 3D) reduces the effects of overlap, providing improved characterization of mammographic findings. However, the dose may double as compared with mammography. This study presents results of Contrast to Noise Ratio (CNR) and image quality evaluation on Siemens mammography equipment Mammomat Inspiration with tomosynthesis. The CNR was determined with Polymethylmethacrylate (PMMA) layers of 20 to 70 mm thick and an aluminum foils of 0,2 mm thickness and area of 10 mm². Image quality was assessed with the ACR Breast Simulator. In the evaluation of image quality, the detectability of fibers and masses was identical in 2D and 3D systems. Displaying fibers were 4,5 and 4 mass in both modes. In 2D mode were identified 3,5 microcalcifications groups, and 3D showed 3 groups. The Mean Glandular Dose (MGD) for the simulator in 2D mode was 1,17 mGy and 2,35 mGy for the 3D mode. The result reinforces the importance of quality control in the process of obtaining the images and obtained in accordance CNR values, ensuring image quality and compatible dose in 2D and 3D processes. (author)

  6. Quality control in breast tomosynthesis

    International Nuclear Information System (INIS)

    In Brazil breast cancer is the most common and the leading cause of death among women, with estimated 57,000 new cases in 2014. The mammography (2D) plays an important role in the early detection of breast cancer, but in some cases can be difficult to detect malignant lesions due overlap of breast tissues. The Breast Digital Tomosynthesis (BDT: 3D) reduces the effects of overlap, providing improved characterization of mammographic findings. However, the dose may double as compared to the mammography. This study presents results of Contrast Ratio Noise tests (CRN) and quality image on a Siemens mammography equipment Mammomat Inspiration with tomosynthesis. The CRN was determined with plates Polymethylmethacrylate (PMMA) of 20 to 70 mm thickness and an aluminum plate of 10 mm2 and 0.2 mm thickness. Image quality was assessed with the ACR Breast Simulator. In assessment of image quality, the detectability of fibers and masses was identical in 2D and 3D systems. Were visualized 4.5 fibers and 4 mass in both modes. In 2D mode groups have been identified 3.5 microcalcifications, and 3D were 3 groups. The Mean Glandular Dose for the simulator in 2D mode was 1.17 mGy and 2.35 mGy for the 3D mode. The result reinforces the importance of quality control in the process of obtaining the images and obtained in accordance CRN values, ensuring image quality and dose compatible in 2D and 3D processes

  7. ASCAT Scatterometer Wind Quality Control

    Science.gov (United States)

    Portabella, M.; Stoffelen, A.; Verhoef, A.; Verspeek, J.

    2010-12-01

    The so-called Advanced scatterometer (ASCAT), onboard MetOp-A satellite was successfully launched on October 19 2006. ASCAT derived sea surface wind field observations are well within the mission accuracy requirements. An important part of the Numerical Weather Prediction Satellite Application Facility (NWP-SAF) ASCAT Data Wind Processor (AWDP) is the wind data quality control (QC). This paper shows the implementation of a new QC procedure, based on the wind inversion residual, which significantly improves the effectiveness of the scatterometer wind data QC.

  8. Endomyocardial biopsy

    International Nuclear Information System (INIS)

    As the result of recent improvements in catheter design and pathologic interpretation, transvascular endomyocardial biopsy has become an important component in the invasive evaluation of patients with known or suspected primary myocardial dysfunction. Because significant controversy remains about the definition, frequency, natural history, and optimal treatment, of many of these myocardial disorders, however, use of the endomyocardial biopsy in the routine evaluation of patients with myocardial disease varies from center to center. This chapter focuses on the currently available techniques for endomyocardial histology appears most valuable, rather than on a precise listing of current indications for this procedure

  9. 33 CFR 385.21 - Quality control.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Quality control. 385.21 Section... Processes § 385.21 Quality control. (a) The Corps of Engineers and the non-Federal sponsor shall prepare a quality control plan, in accordance with applicable Corps of Engineers regulations, for each product...

  10. 14 CFR 21.139 - Quality control.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Quality control. 21.139 Section 21.139... PROCEDURES FOR PRODUCTS AND PARTS Production Certificates § 21.139 Quality control. The applicant must show that he has established and can maintain a quality control system for any product, for which...

  11. Lymph node biopsy

    Science.gov (United States)

    Biopsy - lymph nodes; Open lymph node biopsy; Fine needle aspiration biopsy; Sentinel lymph node biopsy ... A lymph node biopsy is done in an operating room in a hospital. Or, it is done at an outpatient surgical center. The ...

  12. Ureteral retrograde brush biopsy

    Science.gov (United States)

    Biopsy - brush - urinary tract; Retrograde ureteral brush biopsy cytology; Cytology - ureteral retrograde brush biopsy ... to be biopsied is rubbed with the brush. Biopsy forceps may be used instead to collect a ...

  13. Quality assurance and quality control in monitoring programs

    Science.gov (United States)

    Shampine, W.J.

    1993-01-01

    There are three general characteristics of the data to be collected in a monitoring program that should be met in order to maximize the use and value of the data: the data quality should be known the data type and quality should be consistent and comparable, and the data should be available and accessible. Potential problems with each of these characteristics are addressed effectively by quality assurance and quality control. One of the most important aspects of quality assurance in a monitoring program is the development of a quality assurance plan, which should identify clearly the quality of the data needed and describe in detail the planned actions to provide confidence that the program will meet its stated objectives. Quality control data, which allow for the quality and suitability of the environmental data to be evaluated and ascertained, should be collected and utilized as an integral part of the QA effort associated with a monitoring program.

  14. Antibodies in the diagnosis of coeliac disease: a biopsy-controlled, international, multicentre study of 376 children with coeliac disease and 695 controls.

    Directory of Open Access Journals (Sweden)

    Johannes Wolf

    Full Text Available Diagnosis of coeliac disease (CD relies on a combination of clinical, genetic, serological and duodenal morphological findings. The ESPGHAN suggested that biopsy may not be necessary in all cases. New guidelines include omission of biopsy if the concentration of CD-specific antibodies exceeds 10 times the upper limit of normal (10 ULN and other criteria are met. We analysed the 10 ULN criterion and investigated multiple antibody-assays. Serum was collected from 1071 children with duodenal biopsy (376 CD patients, 695 disease-controls. IgA-antibodies to tissue transglutaminase (IgA-aTTG, IgG-antibodies to deamidated gliadin peptides (IgG-aDGL and IgA-endomysium antibodies (IgA-EMA were measured centrally. We considered 3 outcomes for antibody test procedures utilizing IgA-aTTG and/or IgG-aDGL: positive (≥10 ULN, recommend gluten-free diet, negative (90% and PPV/NPV >95%. These stringent conditions were met for appropriate antibody-procedures over a prevalence range of 9-57%. By combining IgG-aDGL with IgA-aTTG, one could do without assaying total IgA. The PPV of IgG-aDGL was estimated to be extremely high, although more studies are necessary to narrow down the LCB. The proportion of patients requiring a biopsy was <11%. The procedures were either equivalent or even better in children <2 years compared to older children. All 310 of the IgA-aTTG positive children were also IgA-EMA positive. Antibody-assays could render biopsies unnecessary in most children, if experienced paediatric gastroenterologists evaluate the case. This suggestion only applies to the kits used here and should be verified for other available assays. Confirming IgA-aTTG positivity (≥10 ULN by EMA-testing is unnecessary if performed on the same blood sample. Prospective studies are needed.

  15. Quality control guarantees the safety of radiotherapy

    International Nuclear Information System (INIS)

    While radiotherapy equipment has seen some decisive improvements in the last few decades, the technology has also become more complicated. The advanced equipment produces increasingly good treatment results, but the condition of the equipment must be controlled efficiently so as to eliminate any defects that might jeopardise patient safety. The quality assurance measures that are taken to show that certain equipment functions as required are known as quality control. The advanced equipment and stricter requirements set for the precision of radiotherapy have meant that more attention must be paid to quality control. The present radiation legislation stipulates that radiotherapy equipment must undergo regular quality control. The implementation of the quality control is supervised by the Finnish Centre for Radiation and Nuclear Safety (STUK). Hospitals carry out quality control in accordance with a programme approved by STUK, and STUK inspectors periodically visit hospitals to check the results of quality control. (orig.)

  16. Radiopharmaceutical quality control-Pragmatic approach

    International Nuclear Information System (INIS)

    The quality control must be considered in a practical manner. The radiopharmaceuticals are drugs. They must satisfy the quality assurance control. These products are then conform to Pharmacopeia. But sometimes the user must control some data especially radiochemical purity and pH value. On all the administered solutions four controls are compulsory: radionuclide identity, administered radioactivity, organoleptic character and pH

  17. Statistical Control of Measurement Quality

    International Nuclear Information System (INIS)

    Effective nuclear materials management, and hence design and operation of associated material control systems, depend heavily on the quality of the quantitative data on which they are based. Information concerning the reliability of the measurement methods employed is essential to both the determination of data requirements and the evaluation of results obtained. Any method of analysis should be (1) relatively free from bias and (2) reproducible, or, in more usual terminology, precise. Many statistical techniques are available to evaluate and control the reproducibility of analytical results. Economical and effective experimental designs have been developed for the segregation of different sources of measurement error. Procedures have been developed or adapted tot use in maintaining and controlling the precision of routine measurements. All of these techniques require that at least some measurements must be duplicated, but duplication of all measurements can be justified only when the detection of every gross error, or mistake, is extremely important. Three types of measurement bias can be considered: (1) bias relative to a standard, (2) bias relative to prior experience, and (3) bias relative to a group. The first refers to the degree to which the measurements obtained deviate systematically from some ''standard'' which is unbiased either (1) by definition, or (2) because all known sources of bias have been removed. The second in concerned with the presence of systematic differences over a period of time. The third type of bias concerns the relationship between different physical entities or individuals at a given time. Recent developments in statistical methodology applicable to the evaluation of all three types of bias are discussed. Examples of the use of the statistical techniques discussed on Hanford data are presented. (author)

  18. Local Control Following Permanent Prostate Brachytherapy: Effect of High Biologically Effective Dose on Biopsy Results and Oncologic Outcomes

    International Nuclear Information System (INIS)

    Purpose: To determine factors that influence local control and systemic relapse in patients undergoing permanent prostate brachytherapy (PPB). Methods and Materials: A total of 584 patients receiving PPB alone or PPB with external beam radiation therapy (19.5%) agreed to undergo prostate biopsy (PB) at 2 years postimplantion and yearly if results were positive or if the prostate-specific antigen (PSA) level increased. Short-term hormone therapy was used with 280 (47.9%) patients. Radiation doses were converted to biologically effective doses (BED) (using α/β = 2). Comparisons were made by chi-square analysis and linear regression. Survival was determined by the Kaplan-Meier method. Results: The median PSA concentration was 7.1 ng/ml, and the median follow-up period was 7.1 years. PB results were positive for 48/584 (8.2%) patients. Positive biopsy results by BED group were as follows: 22/121 (18.2%) patients received a BED of ≤150 Gy; 15/244 (6.1%) patients received >150 to 200 Gy; and 6/193 (3.1%; p 200 Gy. Significant associations of positive PB results by risk group were low-risk group BED (p = 0.019), intermediate-risk group hormone therapy (p = 0.011) and BED (p = 0.040), and high-risk group BED (p = 0.004). Biochemical freedom from failure rate at 7 years was 82.7%. Biochemical freedom from failure rate by PB result was 84.7% for negative results vs. 59.2% for positive results (p 200 Gy with an α/β ratio of 2 yields 96.9% local control rate. Failure to establish local control impacts survival.

  19. Experimental study of bleeding control on liver biopsy in rabbit: N-butyl 2-cyanoacrylate(NBCA) injection and RF electrocauterization

    International Nuclear Information System (INIS)

    To evaluate the hemostatic effect of N-butyl 2-cyanoacrylate(NBCA) injection and RF electrocauterization of the tract after fine needle biopsy of the liver, and the histopathologic changes of the liver. Three lobes of rabbit liver were selected and separately punctured four times with 21 gauge biopsy needles. According to the hemostatic procedure on fine needle biopsy, three groups (1, 2, 3) were found : group 1, in which there was no maneuver for bleeding control, was the control group; group 2, in which NBCA was injected into the puncture tract while slowly removing the needle; group 3, in which RF electrocauterization of the tract was carried out. After completely removing the needle, each group was evaluated for amount of bleeding and histologic change. The amount of bleeding was 0.407gm ±0.245 in group 1, 0.028gm ± 0.036 in group 2 and 0.035gm ±0.028 in group 3. As compared with the control group(group 1), injecting NBCA into the biopsy tract(P=0.0002) and RF electrocauterization of the tract(P=0.0003) significantly reduced the amount of bleeding after liver biopsy. The amount of bleeding was not statistically different between group 2 and 3, however (P=0.58). In Group 1, the tract was fully filled with blood. Group 2 showed NBCA embolized in the biopsy tract, adhering to hepatocytes and mixed with blood; small vessels adjacent to the puncture tract were filled with NBCA. Group 3 showed tissue degeneration, including necrosis of hepatocytes, vacuolation and neutrophil infiltration. Injection of NBCA and RF electrocauterization of the tract after puncture of the liver for biopsy efficiently controlled bleeding. In particular, the efficiency of NBCA injection was due to its effect of plugging the tract and causing the embolization of adjacent small vessels. With regard to procedural handling, RF electrocauterization of the tract is superior to injection of NBCA

  20. Quality control of the crude oil derivatives

    International Nuclear Information System (INIS)

    OKTA is crude oil refinery and its primary activity is production of oil derivates and their distribution in order to fulfill Macedonian market with products in accordance with national standards that are in coordination with European standards from January 2004. Quality is multidisciplinary category consisted of many function. One of the functions of quality assurance is quality control. All employees should be concerned for the control that means also a big responsibility for them. For this reason, a competent team from several departments work and rise all knowledge and experience in providing production of final products with properties that satisfy the customer needs and are established with quality certificate. OKTA assures the established final products quality with quality control of crude oil, intermediates and final products, grants quality certificate, guarantee the quality and control the gas stations in order to satisfy the customers. (Author)

  1. Audit and internal quality control in immunohistochemistry

    OpenAIRE

    Maxwell, P; McCluggage, W

    2000-01-01

    Aims—Although positive and negative controls are performed and checked in surgical pathology cases undergoing immunohistochemistry, internal quality control procedures for immunohistochemistry are not well described. This study, comprising a retrospective audit, aims to describe a method of internal quality control for immunohistochemistry. A scoring system that allows comparison between cases is described.

  2. MAIN PROBLEMS OF CONTROLLING OF THE QUALITY

    Directory of Open Access Journals (Sweden)

    Orlov A. I.

    2015-09-01

    Full Text Available Controlling of statistical methods to ensure product quality is the special case of controlling organizational and economic methods of management. Today, controlling in the practice of management of Russian companies is understood as "the system of information-analytical and methodological support to achieve their goals." The controller is developing a decision-making rules, the head takes decisions on the basis of these rules. We proved the concept of "controlling of methods". Innovation in management is based, in particular, on the use of new adequate organizational-economic (as well as economicmathematical and statistical methods. Controlling in this area - is the development and application procedures of compliance management used and newly developed (implemented organizationaleconomic methods for the task. Thus, the methodology for controlling is of great practical value in any field in which the actions (operations must be carried out in accordance with certain rules (regulations, standards, guidelines, as in any such area in which we need to use development and application procedures of compliance management used and the newly established (implemented rules for solution of tasks assigned to the organization. In this article, we select a area of controlling as controlling quality, and we discuss its main issues. This is about controlling of organizational-economic methods to ensure product quality, especially about the statistical methods based on probability theory and mathematical statistics. We consider the analysis and synthesis of plans of statistical quality control, optimization options plans of statistical control, truncated plans. Are discussed the differences control plans provider and the consumer, the allocation of units formless (liquid, gas products, the selection of a random sample of the statistical quality control of products, lower estimate of the required sample size. It is established, that is not always necessary

  3. Extraction of high-quality epidermal RNA after ammonium thiocyanate-induced dermo-epidermal separation of 4 mm human skin biopsies

    DEFF Research Database (Denmark)

    Clemmensen, Anders; Thomassen, Mads; Clemmensen, Ole; Tan, Qihua; Kruse, Torben A; Petersen, Thomas K; Andersen, Flemming; Andersen, Klaus E

    2009-01-01

    different incubation times; (ii) the amount and quality of extractable epidermal RNA and (iii) its impact on sample RNA expression profiles assessed by large-scale gene expression microarray analysis in both normal and inflamed skin. At 30-min incubation, the split between dermis and epidermis was not......, and satisfactory amounts of high-quality RNA were obtained. Hybridization to Affymetrix HG_U133A 2.0 GeneChips showed that ammonium thiocyanate incubation had a minute effect on gene expression resulting in only one significantly downregulated gene (cystatin E/M). We conclude that epidermis can be...... reproducibly and almost completely separated from the dermis of 4 mm skin biopsies by 30 min incubation in 3.8% ammonium thiocyanate combined with curettage of the dermal surface, producing high-quality RNA suitable for transcriptional analysis. Our refined method of dermo-epidermal separation will undoubtedly...

  4. Quality Control in Small Groups

    Science.gov (United States)

    Lemmens, L. F.

    2008-11-01

    The smallness of some groups in a set up to control the quality of a service using questionnaires limits the size of the samples, this limitation has several consequences. Indeed the common approach used for relatively large groups, based on the central limit theorem and the law of large numbers, cannot be used anymore to construct estimators for the parameters of the model. Using an inverse probability will lift these restrictions. A questionnaire is a collection of items. In an item the respondent indicates on a Likert scale his or her agreement with a statement. Dimensions are a set of items dealing with one aspect of the service. In a questionnaire several dimensions are addressed but usually the items are presented in a random sequence. The model for an item is hierarchical with following components: a multivariate hypergeometric model takes the sampling in a finite population into account, the multinomial serves as a prior for the sampling and the Dirichlet-distribution serves as a prior for the multinomials. The composition of dimensions allows to use the posterior for one of the items as a prior for another item of that dimension and so on. After analysis of several questionnaires using this model, the reliability of the responses from some respondents turned out to be a key-problem, in the sense the responses can be classified into at least two classes and a decision rule had to be developed to neglect some of them. The influence of rejecting some answers, on the confidence for the most plausible statement can be estimated. This leads often to the result that there is only minimal evidence for the most probable statement.

  5. Nasal mucosal biopsy

    Science.gov (United States)

    Biopsy - nasal mucosa; Nose biopsy ... to fast for a few hours before the biopsy. ... Nasal mucosal biopsy is usually done when abnormal tissue is seen during examination of the nose. It may also be done ...

  6. Bone lesion biopsy

    Science.gov (United States)

    Bone biopsy; Biopsy - bone ... is sent to a lab for examination. Bone biopsy may also be done under general anesthesia to ... remove the bone can be done if the biopsy exam shows that there is an abnormal growth ...

  7. Biopsy - biliary tract

    Science.gov (United States)

    Cytology analysis - biliary tract; Biliary tract biopsy ... A sample for a biliary tract biopsy can be obtained in different ways. A needle biopsy can be done if you have a well-defined tumor. The biopsy site ...

  8. Establishment for quality control of experimental animal

    International Nuclear Information System (INIS)

    Until now, because we have imported experimental animal from foreign experimental animal corporation, we could have saved money by establishing the quality control of animal in barrier system. In order to improve the quality of animal experiment and efficiency of biomedical study, it is indispensable to control many factors that effect in the experiment. Therefore, it is essential to organize the system of laboratory animal care for enhancing reliability and revivability of experimental results. The purpose of the present investigation was to establish the quality control system of experimental animals that we can provide good quality animals according to the experimental condition of each investigator although the exact quality control system to estimate the infection of bacteria and virus easily remains ill-defined yet. Accordingly, we established the useful quality control system for microbiologic monitoring and environmental monitoring to protect experimental animal from harmful bacteria and virus

  9. Establishment for quality control of experimental animal

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Tae Hwan; Kim, Soo Kwan; Kim, Tae Kyoung

    1999-06-01

    Until now, because we have imported experimental animal from foreign experimental animal corporation, we could have saved money by establishing the quality control of animal in barrier system. In order to improve the quality of animal experiment and efficiency of biomedical study, it is indispensable to control many factors that effect in the experiment. Therefore, it is essential to organize the system of laboratory animal care for enhancing reliability and revivability of experimental results. The purpose of the present investigation was to establish the quality control system of experimental animals that we can provide good quality animals according to the experimental condition of each investigator although the exact quality control system to estimate the infection of bacteria and virus easily remains ill-defined yet. Accordingly, we established the useful quality control system for microbiologic monitoring and environmental monitoring to protect experimental animal from harmful bacteria and virus.

  10. Quality control in radiochemical analysis

    International Nuclear Information System (INIS)

    Whenever analytical data are to be used as a basis for a scientific study or even for monitoring purposes it is necessary to have information on the quality of the analyses. It is much better if this quality can be expressed in numerical form rather than subjectively and it is also better if the data are part of a continuing programme. All laboratories are involved in this question of analytical quality but the degree to which they develop the required information is highly variable. The present paper attempts to describe an ideal system and to present some data relating to analysis of seawater

  11. Quality control education in the community college

    Science.gov (United States)

    Greene, J. Griffen; Wilson, Steve

    1966-01-01

    This paper describes the Quality Control Program at Daytona Beach Junior College, including course descriptions. The program in quality control required communication between the college and the American Society for Quality Control (ASQC). The college has machinery established for certification of the learning process, and the society has the source of teachers who are competent in the technical field and who are the employers of the educational products. The associate degree for quality control does not have a fixed program, which can serve all needs, any more than all engineering degrees have identical programs. The main ideas which would be common to all quality control programs are the concept of economic control of a repetitive process and the concept of developing individual potentialities into individuals who are needed and productive.

  12. Quality control of mammographic systems

    International Nuclear Information System (INIS)

    High quality in mammography is a difficult objective to achieve, that is the reason for what efforts are made in order to improve equipment, to offer good combinations screen-film, and professional staff dedicated to this technique

  13. 7 CFR 981.442 - Quality control.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Quality control. 981.442 Section 981.442 Agriculture... Administrative Rules and Regulations § 981.442 Quality control. (a) Incoming. Pursuant to § 981.42(a), the..., see the List of CFR Sections Affected, which appears in the Finding Aids section of the printed...

  14. 30 CFR 74.6 - Quality control.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Quality control. 74.6 Section 74.6 Mineral... of the CMDPSU will be maintained in production through adequate quality control procedures, MSHA and... DUST SAMPLING DEVICES Approval Requirements for Coal Mine Dust Personal Sampler Unit § 74.6...

  15. Quality control within the windmill branch

    International Nuclear Information System (INIS)

    The aim of the project was to improve the quality of Danish-produced wind turbines by initiating quality control and working out general technical guidelines compatible with European standards so that these products can be authorized internationally. Guidelines for blade production, and purchase of gear boxes are presented in addition to an explanation of the concept of quality control. Administrational procedures in relation to authorization are also explained. (AB)

  16. Symbolic quality control for multimedia applications

    OpenAIRE

    Combaz J.; Fernandez J.-C.; Sifakis J.; Strus L.

    2008-01-01

    We present a fine grain quality control method for multimedia applications. The method takes as input an application software composed of actions. The execution times of actions are unknown increasing functions of quality level parameters. The method allows the construction of a Controller which computes adequate action schedules and corresponding quality levels, so as to meet QoS requirements for a given platform. These include requirements for safety (action deadlines are met) as well optim...

  17. Parotid gland biopsy compared with labial biopsy in the diagnosis of patients with primary Sjogren's syndrome

    NARCIS (Netherlands)

    Pijpe, J.; Kalk, W. W. I.; van der Wal, J. E.; Vissink, A.; Kluin, Ph. M.; Roodenburg, J. L. N.; Bootsma, H.; Kallenberg, C. G. M.; Spijkervet, F. K. L.

    2007-01-01

    Objective. To assess the value of the parotid biopsy as a diagnostic tool for primary Sjogren's syndrome ( pSS), and to compare the parotid biopsy and the labial biopsy with regard to diagnostic value and biopsy-related morbidity. Methods. In 15 consecutive patients with pSS and 20 controls, the par

  18. Quality-control analytical methods: continuous quality improvement.

    Science.gov (United States)

    Venti, Eden M

    2006-01-01

    It is vital that all compounding pharmacies have a continuous quality improvement program in place by way of standard operating procedures to assure that patients receive high-quality preparations. The program should take into consideration any federal and state regulatory requirements, as well as professional association expectations. Quality control measurements and regular review of those measurements are the foundations of a good quality plan. All pharmacy personnel should be aware of the importance of reporting potential internal quality concerns or problems and should be encouraged to do so without fear of repercussions. Ideally, an error-free compounding pracitice would be the goal. Since this is not practical, quality issues should not be viewed as problems, but as opportunities to improve compounding practices by correcting, before they become pervasive, the processes used in the preparation of prescriptions. PMID:23974418

  19. Quality control in the radioactive waste management

    International Nuclear Information System (INIS)

    Radioactive waste management as in industrial activities must mantain in all steps a quality control programme. This control extended from materials acquisition, for waste treatment, to the package deposition is one of the most important activities because it aims to observe the waste acceptance criteria in repositories and allows to guarantee the security of the nuclear facilities. In this work basic knowledges about quality control in waste management and some examples of adopted procedures in other countries are given. (author)

  20. Nonmicrobial alternative to reagent quality control testing.

    OpenAIRE

    Reynolds, S M

    1982-01-01

    The traditional approach to quality control in microbiology involves the routine testing of both media and reagents with live microbial cultures. This is expensive, time consuming, and subject to the variables associated with the use of live organisms. A system of reagent quality control based on the pure chemical form of the metabolic end products important to the identification of the Enterobacteriaceae was evaluated. The metabolite reagent control system is simple, reliable, and extremely ...

  1. Sensometrics for Food Quality Control

    OpenAIRE

    Brockhoff, Per B.

    2011-01-01

    The industrial development of innovative and succesful food items and the measuring of food quality in general is difficult without actually letting human beings evaluate the products using their senses at some point in the process. The use of humans as measurement instruments calls for special attention in the modelling and data analysis phase. In this paper the focus is on sensometrics – the „metric“ side of the sensory science field. The sensometrics field is introduced and related to the ...

  2. Control by quality: proposition of a typology.

    Science.gov (United States)

    Pujo, P; Pillet, M

    The application of Quality tools and methods in industrial management has always had a fundamental impact on the control of production. It influences the behavior of the actors concerned, while introducing the necessary notions and formalizations, especially for production systems with little or no automation, which constitute a large part of the industrial activity. Several quality approaches are applied in the workshop and are implemented at the level of the control. In this paper, the authors present a typology of the various approaches that have successively influenced control, such as statistical process control, quality assurance, and continuous improvement. First the authors present a parallel between production control and quality organizational structure. They note the duality between control, which is aimed at increasing productivity, and quality, which aims to satisfy the needs of the customer. They also note the hierarchical organizational structure of these two systems of management with, at each level, the notion of a feedback loop. This notion is fundamental to any kind of decision making. The paper is organized around the operational, tactical, and strategic levels, by describing for each level the main methods and tools for control by quality. The overview of these tools and methods starts at the operational level, with the Statistical Process Control, the Taguchi technique, and the "six sigma" approach. On the tactical level, we find a quality system approach, with a documented description of the procedures introduced in the firm. The management system can refer here to Quality Assurance, Total Productive Maintenance, or Management by Total Quality. The formalization through procedures of the rules of decision governing the process control enhances the validity of these rules. This leads to the enhancement of their reliability and to their consolidation. All this counterbalances the human, intrinsically fluctuating, behavior of the control

  3. Quality assurance and quality control in the radon measurement industry

    International Nuclear Information System (INIS)

    Since the release of survey results by the consumer advocacy group BUYERS-UP, QA/QC has bee the buzz word among everyone involved with Radon/Radon Decay Product measurement. This paper presents a discussion in generality of the roles of Quality Assurance and Quality Control in the Radon Measurement Industry, the strengths and weaknesses of QA/QC in radon measurement and the significance of research in QA/QC for radon measurement

  4. TRAINING SYSTEM OF FUTURE SPECIALISTS: QUALITY CONTROL

    Directory of Open Access Journals (Sweden)

    Vladimir A. Romanov

    2015-09-01

    Full Text Available The aim of the investigation is development of innovative strategy of quality control training of engineers and skilled workers (hereinafter – future specialists in educational professional organizations on the principles of social partnership.Methods. Theoretic: theoretic and methodological analysis, polytheoretic synthesis, modeling. Empirical: research and generalization of the system, process and competence – based approaches experience, experiment, observation, surveys, expert evaluation, SWOT-analysis as a method of strategic planning which is to identify the internal and external factors (socio-cultural of the organization surrounding.Results. The strategy of the development of the process of quality control training in educational professional organizations and a predictive model of the system of quality control training for future engineers and workers have been created on the analysis and synthesis of a quantitative specification of the quality, the obtained experience and success in control training of future specialists in educational professional organizations in recent economic and educational conditions.Scientific novelty. There has been built a predicative model of quality control training of future specialists to meet modern standards and the principles of social partnership; the control algorithm of the learning process, developed in accordance with the standards (international of quality ISO in the implementation of the quality control systems of the process approach (matrix-based responsibility, competence and remit of those responsible for the education process in the educational organization, the «problem» terms and diagnostic tools for assessing the quality of professional training of future specialists. The perspective directions of innovation in the control of the quality of future professionals training have been determined; the parameters of a comprehensive analysis of the state of the system to ensure the

  5. Sensometrics for Food Quality Control

    DEFF Research Database (Denmark)

    Brockhoff, Per B.

    2011-01-01

    attention in the modelling and data analysis phase. In this paper the focus is on sensometrics – the „metric“ side of the sensory science field. The sensometrics field is introduced and related to the fields of statistics, chemometrics and psychometrics. Some of the most commonly used sensory testing......The industrial development of innovative and succesful food items and the measuring of food quality in general is difficult without actually letting human beings evaluate the products using their senses at some point in the process. The use of humans as measurement instruments calls for special...

  6. [Quality control of printed patient information].

    Science.gov (United States)

    Herm, Kerstin; Linden, Michael

    2013-05-01

    Printed material is an important part in patient information and is called bibliotherapy. It is subject to quality control similar to any other types of treatment. This paper presents an outline of important quality criteria and methods of quality control. Important quality criteria are: (a) Correctness and validity of content evaluated by mentioning the expertise of the authors, appraisal through external experts, reference to scientific literature, and empirical tests of the content, (b) Readability in respect to text structure measured by the "Flesch-Reading-Ease-Formula" supported by fair graphical design including fond and structure of text, (c) Comprehensibility tested by feedback of patients or standardized by the Hamburg comprehensibility rating, (d) Utility including securing availability, acceptance, differential indication and use. Writing and publication of patient leaflets must be accompanied by quality control measures. PMID:23446824

  7. Control mechanisms for assuring better IS quality:

    OpenAIRE

    Pivka, Marjan

    1998-01-01

    The software domain is faced with a number of quality assurance and process improvement models. Business managers are under pressure from many different kinds of assessments for their operations, products and services. Accounting departments are audited by financial auditors. What about information systems? Do we have a universal model on how to achieve required IS quality? This paper deals with the definition of IS quality and the influence of different control mechanisms on IS. The results ...

  8. PET/CT instrumentation: Quality assurance and quality control

    International Nuclear Information System (INIS)

    Improvement in quality assurance in Nuclear Medicine and in particular, in quality control of related equipment is a major field of interest of the International Atomic Energy Agency (IAEA). Several technical documents pertaining to scintigraphic imaging have been published and are being used as reference manuals by many professionals in the field (e.g., TECDOC 317, TECDOC 602, STI/PUB 1141). Positron emission tomography (PET) scanners and related performance assessment and quality control were not included in the previously published documents, as PET has been mainly a research tool, with limited worldwide distribution until the 90's. The tremendous role played presently by PET and PET/CT in whole-body oncology for lesion detection, staging and follow-up as well as the increasing role for PET in cardiology and neurology, associated with increasing reimbursement of multiple PET indications have prompted the need for updated guidelines specific to PET and PET/CT in terms of acceptance testing as well as quality control and assurance. The aim of this work is to present an overview of acceptance testing and quality assurance and control for PET and PET/CT

  9. Net analyte signal based statistical quality control

    NARCIS (Netherlands)

    Skibsted, E.T.S.; Boelens, H.F.M.; Westerhuis, J.A.; Smilde, A.K.; Broad, N.W.; Rees, D.R.; Witte, D.T.

    2005-01-01

    Net analyte signal statistical quality control (NAS-SQC) is a new methodology to perform multivariate product quality monitoring based on the net analyte signal approach. The main advantage of NAS-SQC is that the systematic variation in the product due to the analyte (or property) of interest is sep

  10. A quality control manual for oral radiology

    International Nuclear Information System (INIS)

    A quality control manual for oral radiology is showed. The X-ray equipment used for this activity is described, such as the X-ray tube, collimator. The high tension in X-ray tube, the spectra, the quality and the quantity of radiation and the X-ray intensity are also analysed. (C.G.C.)

  11. The regulatory maze of quality control

    International Nuclear Information System (INIS)

    The appropriateness of specific procedures within a quality control program becomes difficult to assess when an attempt is made to collate all of the available information. This task is discussed from the perspective of the Joint Commission (JCAH Accreditation Manual), HHS(quality assurance program recommendations), equipment manufacturers maintenance schedules, and radiology administrative cost concerns

  12. Production and quality control of iodine-123

    International Nuclear Information System (INIS)

    The various methods for production and quality control are discussed. The author feels the 123Xe-123I generator is the best method of production. Preparation and use of 123I-labeled compounds are also considered

  13. Quality Controlled Local Climatological Data (QCLCD) Publication

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Quality Controlled Local Climatological Data (QCLCD) contains summaries from major airport weather stations that include a daily account of temperature extremes,...

  14. Bone lesion biopsy

    Science.gov (United States)

    Bone biopsy; Biopsy - bone ... needle is gently pushed and twisted into the bone. Once the sample is obtained, the needle is ... sample is sent to a lab for examination. Bone biopsy may also be done under general anesthesia ...

  15. Muscle biopsy (image)

    Science.gov (United States)

    A muscle biopsy involves removal of a plug of tissue usually by a needle to be later used for examination. Sometimes ... there is a patchy condition expected an open biopsy may be used. Open biopsy involves a small ...

  16. Bone biopsy (image)

    Science.gov (United States)

    A bone biopsy is performed by making a small incision into the skin. A biopsy needle retrieves a sample of bone and it ... examination. The most common reasons for bone lesion biopsy are to distinguish between benign and malignant bone ...

  17. Guidelines for quality control in digital fluoroscopy

    International Nuclear Information System (INIS)

    In the framework of European project DIMOND III, a document on quality control in digital fluoroscopy was drafted to offer means for equipment testing to ensure that specific requirements are fulfilled resulting in optimum image quality a minimum patient dose. The results are summarised in this paper. The work involves review of documents and publications in digital fluoroscopy equipment testing. The study takes into account not the efficiency of the tests but also their applicability in daily practice. The results are series of quality control tests and guidelines for evaluating systems used in fluoroscopically guided interventional procedures. (author)

  18. Quality assurance and quality control in mammography: A review

    International Nuclear Information System (INIS)

    A mammogram is among the most technically demanding radiographic procedures. The early detection of breast cancer relies on the radiologist's ability to perceive subtle changes in the image that are only perceptible with high-quality imaging. Early detection of breast cancer is only as reliable as the mammogram with which a diagnosis is made, and a mammogram is only as accurate as the system that produces it. A quality assurance (QA) program maximizes the likelihood that the mammographic images will provide adequate diagnostic information for the least possible radiation exposure and cost to the patient. The QA program monitors each phase of operation of the imaging facility beginning with the request for an examination and ending with the interpretation of the referring physician and ensures that the imaging equipment used for the examination will yield the information desired. Because image quality is the most important technical aspect of mammography, this review summarizes the most important QA and quality control issues

  19. Quality control of dental radiohy at Iran

    International Nuclear Information System (INIS)

    A quality control program for dental radiography, in order to be sure that each radiographic operation with respect to its clinical difficulties to obtain images with high quality and gain proper information to be used in therapy with the lowest dose and cost is developed. In this program 20 radiography centers evaluated and parameters to control dose rate and images quality are considered. The results show inter oral films reduced to 408 and extra oral films reduced to 22 films in a week. The measured exposure from out coming of apparatus depends on various parameters which corrected errors is reduced to 5.35 m Sv.Unwanted exposure of operators and common people which occurred because of ignorance to the exposure is reduced to 0.88 m Sv and 1 m Sv in a week therefore, the importance of quality control program is obvious

  20. Network-based production quality control

    Science.gov (United States)

    Kwon, Yongjin; Tseng, Bill; Chiou, Richard

    2007-09-01

    This study investigates the feasibility of remote quality control using a host of advanced automation equipment with Internet accessibility. Recent emphasis on product quality and reduction of waste stems from the dynamic, globalized and customer-driven market, which brings opportunities and threats to companies, depending on the response speed and production strategies. The current trends in industry also include a wide spread of distributed manufacturing systems, where design, production, and management facilities are geographically dispersed. This situation mandates not only the accessibility to remotely located production equipment for monitoring and control, but efficient means of responding to changing environment to counter process variations and diverse customer demands. To compete under such an environment, companies are striving to achieve 100%, sensor-based, automated inspection for zero-defect manufacturing. In this study, the Internet-based quality control scheme is referred to as "E-Quality for Manufacturing" or "EQM" for short. By its definition, EQM refers to a holistic approach to design and to embed efficient quality control functions in the context of network integrated manufacturing systems. Such system let designers located far away from the production facility to monitor, control and adjust the quality inspection processes as production design evolves.

  1. Quality control in 99m technetium radiopharmaceuticals

    International Nuclear Information System (INIS)

    This work means about the quality control in Tc radiopharmaceuticals preparation at hospitalary levels. Several steps must be used in a Nuclear Medicine Laboratory, such as proceeding,radiopharmaceuticals kits preparation, and dispensation materials,glasses,stopper,physical aspects,identification,ph control,storage,and reactif kits

  2. Quality control standards in PGD and PGS.

    Science.gov (United States)

    SenGupta, S B; Dhanjal, S; Harper, J C

    2016-03-01

    Preimplantation genetic diagnosis (PGD) aims to test the embryo for specific conditions before implantation in couples at risk of transmitting genetic abnormality to their offspring. The couple must undergo IVF procedures to generate embryos in vitro. The embryos can be biopsied at either the zygote, cleavage or blastocyst stage. Preimplantation genetic screening uses the same technology to screen for chromosome abnormalities in embryos from patients undergoing IVF procedures as a method of embryo selection. Fluorescence in-situ hybridization was originally used for chromosome analysis, but has now been replaced by array comparative genomic hybridization or next generation sequencing. For the diagnosis of single gene defects, polymerase chain reaction is used and has become highly developed; however, single nucleotide polymorphism arrays for karyomapping have recently been introduced. A partnership between IVF laboratories and diagnostic centres is required to carry out PGD and preimplantation genetic screening. Accreditation of PGD diagnostic laboratories is important. Accreditation gives IVF centres an assurance that the diagnostic tests conform to specified standards. ISO 15189 is an international laboratory standard specific for medical laboratories. A requirement for accreditation is to participate in external quality assessment schemes. PMID:26776824

  3. Quality control of cadweld (mechanical) splices

    International Nuclear Information System (INIS)

    Test data for cadweld splicing of reinforcing steel collected during a study of quality assurance practices on nine nuclear power plant construction projects are presented and evaluated. These data lead to an important hypothesis that the visual inspection identifies procedural deficiencies, and the tensile test identifies material defects. It is also suggested that a material testing program and the visual inspection will detect essentially all substandard cadwell splices. This would permit the deletion of the expensive tensile testing program. Accordingly, most quality control programs require overtesting and overdocumentation of cadweld splices; and furthermore, these programs fail to recognize material defects. The project specifications and quality control requirements for the nine projects are compared. Where possible, these are evaluated against the industry standards and Federal regulations. It is shown that there are a number of deficiencies in these standards, and that in most cases, the testing requirements are not commensurate with the quality that is being achieved in the field

  4. Quality control of a teleradiology system

    Science.gov (United States)

    Lyche, David K.; Willis, Charles E.; Williamson, Morgan P.; Suitor, Charles T.; Romlein, John R.

    1996-04-01

    Teleradiology is being implemented in the U.S. military. Soft-copy reading of computed radiology (CR) images and film-digitizer (FD) images are becoming a common practice. The Medical Diagnostic Imaging Support (MDIS) Office at the Medical Advanced Technology Management Office (MATMO), Fort Detrick, Maryland, installed an 'off-the-shelf' DICOM teleradiology system by which CR images and FD images acquired at Hickam Air Force Base (AFB), Hawaii, are transmitted electronically over a T-1 telecommunications line to Tripler Army Medical Center (TAMC), Hawaii. The goal was to provide a diagnostic quality teleradiology system to the military services to extend the expertise and training of physicians to remote sites. In order to guarantee a diagnostic quality image throughout the system, a rigid set of quality control standards had to be designed and implemented. This poster presents the results of a successful teleradiology implementation where quality control is maintained throughout the imaging chain.

  5. Development of the gaharu oil quality control

    International Nuclear Information System (INIS)

    Gaharu (Agar wood) is a secondary metabolite produces by the Aquilaria spp. and accumulates in the plant cell in oleoresin form. The essential oil known as gaharu oil can be extracted from this oleoresin gaharu via varies extraction method such as the water distillation, solvent extraction, pressurize extraction and etc. The gaharu oil extracted through different methods will give different fragrances. Besides, different source of materials will also give different in chemical profiles. In gaharu oil trading market, most of the buyers request quality assurance from the gaharu oil manufacturer to assure the gaharu oil purchased meets their standard requirement. Since there is a demand on gaharu oil quality assurance then it become a need to develop the gaharu oil quality control method in order to have a standard quality control of gaharu oil presented in a certificate of analysis and verified by laboratory. (author)

  6. Quality Control of Wild Berries Honey Syrup

    Directory of Open Access Journals (Sweden)

    Laura Stan

    2013-11-01

    Full Text Available This paper presents the quality control parameters of wild berries honey syrup . The product was created in laboratory (wild berries: honey, 1:4 w/w and there were no changes recorded in overall quality over 6 months preservation at 1-2°C. Basic quality parameters of the product were evaluated: humidity, pH, acidity, hydroxymethylfurfural, diastase, total sugars and ascorbic acid. Methods developed by Internantional Honey Commission and Romanian Food Quality Standards were applied during this study. The product presented qood quality criteria and it was highly appreciated by consumers who tasted it. This study presents a valuable method to preserve fresh widberries in honey over a long period of time. The economical value of this experiment resides in making these fruits available outside the harvesting season.

  7. Quality control in diagnostic radiology - patient dosimetry

    International Nuclear Information System (INIS)

    In order to establish the Quality Criteria for diagnostic radiographic images in the radiology departments in Republic of Croatia we have started the several Quality Control projects on the field. The measurements are performed according to some methodology recommendations in our law but the methodology, measurement principles, measurement equipment, phantoms, measurable parameters for the good use by radiographers, statistical and numerical evaluation, dosimetric philosophy etc. where first recognized as a private/or group hazard of each person involved in the procedure of evaluation of diagnostic radiology images/diagnosis. The important quality elements of the imaging process are: the diagnostic quality of the radiographic image, the radiation dose to the patient and the choice of the radiographic technique. This depends on the x-ray unit (tube) radiation quality, image processing quality and final image evaluation quality. In this paper we will show how the Quality Control measurements can be easily connected to the dose delivered to the patient for the known diagnostic procedure and how this can be used by radiographers in their daily work. The reproducibility of the x-ray generator was checked before the service calibration and after the service calibration. The table of kV dependence and output dose per mAs was calculated and the ESD (entrance surface dose) was measured/calculated for the specific diagnostic procedure. After the phantom calculation were made and the dose prediction for the given procedure was done, measurements were done on the patients (digital dosemeters, TLD and film dosemeter combinations). We are claiming that there is no need to measure each patient if the proper Quality Control measurements are done and the proper table of ESD for each particular x-ray tube in diagnostic departments is calculated for the radiographers daily use. (author)

  8. Harmonisation Initiatives of Copernicus Data Quality Control

    Science.gov (United States)

    Vescovi, F. D.; Lankester, T.; Coleman, E.; Ottavianelli, G.

    2015-04-01

    The Copernicus Space Component Data Access system (CSCDA) incorporates data contributions from a wide range of satellite missions. Through EO data handling and distribution, CSCDA serves a set of Copernicus Services related to Land, Marine and Atmosphere Monitoring, Emergency Management and Security and Climate Change. The quality of the delivered EO products is the responsibility of each contributing mission, and the Copernicus data Quality Control (CQC) service supports and complements such data quality control activities. The mission of the CQC is to provide a service of quality assessment on the provided imagery, to support the investigation related to product quality anomalies, and to guarantee harmonisation and traceability of the quality information. In terms of product quality control, the CQC carries out analysis of representative sample products for each contributing mission as well as coordinating data quality investigation related to issues found or raised by Copernicus users. Results from the product analysis are systematically collected and the derived quality reports stored in a searchable database. The CQC service can be seen as a privileged focal point with unique comparison capacities over the data providers. The comparison among products from different missions suggests the need for a strong, common effort of harmonisation. Technical terms, definitions, metadata, file formats, processing levels, algorithms, cal/val procedures etc. are far from being homogeneous, and this may generate inconsistencies and confusion among users of EO data. The CSCDA CQC team plays a significant role in promoting harmonisation initiatives across the numerous contributing missions, so that a common effort can achieve optimal complementarity and compatibility among the EO data from multiple data providers. This effort is done in coordination with important initiatives already working towards these goals (e.g. INSPIRE directive, CEOS initiatives, OGC standards, QA4EO

  9. Evaluating quality control of Wikipedia's feature articles

    OpenAIRE

    Lindsey, David

    2010-01-01

    The purpose of this study was to evaluate the effectiveness of Wikipedia’s internal quality control mechanism, the “featured article” process, which assesses articles against a stringent set of criteria. To this end, scholars were asked to evaluate the quality and accuracy of Wikipedia featured articles within their area of expertise. A total of 22 usable responses were collected from a variety of disciplines. Out of the Wikipedia articles assessed, only 12 of 22 were found to pass Wikiped...

  10. Quality assurance/quality control for testing of radioactivity

    International Nuclear Information System (INIS)

    The Testing laboratory of material radioactivity was founded in 1999 on the basis of former Nuclear Research Centre. The primary aim was to test the waste, radioactive polluted materials and apparatus from the shut down nuclear reactor. In 2000 National Accreditation Service of Latvia (LATAK) accredited laboratory. In the following years the enlargement of testing sphere occurred. The aim of this work is the introduction of quality assurance and quality control according to ISO/IEC 17025 standard in the Testing laboratory of material radioactivity State Enterprise 'RAPA' in Salaspils, Latvia. Radioactivity of Cs-137, Co-60, U-238 and Th-232 trees, as well as other radionuclides is measured using the high performance gamma-spectrometry. Testing of different environmental samples and building materials as well as samples irradiated with neutron flux of nuclear reactor and radioactive polluted objects is carried out. Alfa- and beta-radioactivity of waters is tested using OXFORD Tennelec Solo counting system. Other equipment is used to test the radioactive contaminated surfaces, the testing of tritium activity is done with LSC. The 4 year work period on the quality control and quality assurance of the laboratory and the participation in the intercalibration measurements allowed: - to get the laboratory accreditation according to ISO/IEC 17025 standard; - to enlarge the sphere of activities (introducing new methods); - to increase the number of clients; - to increase the number of tested samples from 124 in 2000 to 600 in the 8 months of the year 2003. (authors)

  11. Protein quality control in the nucleus

    DEFF Research Database (Denmark)

    Nielsen, Sofie V.; Poulsen, Esben Guldahl; Rebula, Caio A.;

    2014-01-01

    to aggregate, cells have evolved several elaborate quality control systems to deal with these potentially toxic proteins. First, various molecular chaperones will seize the misfolded protein and either attempt to refold the protein or target it for degradation via the ubiquitin-proteasome system. The...... particularly active in protein quality control. Thus, specific ubiquitin-protein ligases located in the nucleus, target not only misfolded nuclear proteins, but also various misfolded cytosolic proteins which are transported to the nucleus prior to their degradation. In comparison, much less is known about...... these mechanisms in mammalian cells. Here we highlight recent advances in our understanding of nuclear protein quality control, in particular regarding substrate recognition and proteasomal degradation....

  12. Quality control of 11C-carfentanil

    International Nuclear Information System (INIS)

    To study the quality control of 11C-Carfentanil injection, physical, chemical and biological identification were used. The chemical and radiochemical purity of 11C-Carfentanil Injection were detected by HPLC and Flower Count system; measured the quantity of product by LC-MS, specific activity was calculated later; The PTS was used to detect endotoxin, and other quality control methods were put up to guarantee the security of its clinical application. The produce appeared colorless and transparent, the radiochemical purity was more than 98%, content of the endotoxin was less than 5 EU/mL. The result showed that 11C-Carfentanil injection had fulfilled pharmaceutical quality control request and could be applied safely to animal experiment and clinical diagnosis. (authors)

  13. Protein quality control in the bacterial periplasm.

    Science.gov (United States)

    Merdanovic, Melisa; Clausen, Tim; Kaiser, Markus; Huber, Robert; Ehrmann, Michael

    2011-01-01

    Protein quality control involves sensing and treatment of defective or incomplete protein structures. Misfolded or mislocalized proteins trigger dedicated signal transduction cascades that upregulate the production of protein quality-control factors. Corresponding proteases and chaperones either degrade or repair damaged proteins, thereby reducing the level of aggregation-prone molecules. Because the periplasm of gram-negative bacteria is particularly exposed to environmental changes and respective protein-folding stresses connected with the presence of detergents, low or high osmolarity of the medium, elevated temperatures, and the host's immune response, fine-tuned protein quality control systems are essential for survival under these unfavorable conditions. This review discusses recent advances in the identification and characterization of the key cellular factors and the emerging general principles of the underlying molecular mechanisms. PMID:21639788

  14. Frontiers in statistical quality control 11

    CERN Document Server

    Schmid, Wolfgang

    2015-01-01

    The main focus of this edited volume is on three major areas of statistical quality control: statistical process control (SPC), acceptance sampling and design of experiments. The majority of the papers deal with statistical process control, while acceptance sampling and design of experiments are also treated to a lesser extent. The book is organized into four thematic parts, with Part I addressing statistical process control. Part II is devoted to acceptance sampling. Part III covers the design of experiments, while Part IV discusses related fields. The twenty-three papers in this volume stem from The 11th International Workshop on Intelligent Statistical Quality Control, which was held in Sydney, Australia from August 20 to August 23, 2013. The event was hosted by Professor Ross Sparks, CSIRO Mathematics, Informatics and Statistics, North Ryde, Australia and was jointly organized by Professors S. Knoth, W. Schmid and Ross Sparks. The papers presented here were carefully selected and reviewed by the scientifi...

  15. Quality control of nuclear medicine instruments, 1991

    International Nuclear Information System (INIS)

    This document gives detailed guidance on the quality control of various instruments used in nuclear medicine. A first preliminary document was drawn up in 1979. A revised and extended version, incorporating recommended procedures, test schedules and protocols was prepared in 1982. The first edition of 'Quality Control of Nuclear Medicine Instruments', IAEA-TECDOC-317, was printed in late 1984. Recent advances in the field of nuclear medicine imaging made it necessary to add a chapter on Camera-Computer Systems and another on SPECT Systems

  16. Quality control of nuclear medicine instruments 1991

    International Nuclear Information System (INIS)

    This document gives detailed guidance on the quality control of various instruments used in nuclear medicine. A first preliminary document was drawn up in 1979. A revised and extended version, incorporating recommended procedures, test schedules and protocols was prepared in 1982. The first edition of ''Quality Control of Nuclear Medicine Instruments'', IAEA-TECDOC-317, was printed in late 1984. Recent advances in the field of nuclear medicine imaging made it necessary to add a chapter on Camera-Computer Systems and another on SPECT Systems. Figs and tabs

  17. Statistical quality control a loss minimization approach

    CERN Document Server

    Trietsch, Dan

    1999-01-01

    While many books on quality espouse the Taguchi loss function, they do not examine its impact on statistical quality control (SQC). But using the Taguchi loss function sheds new light on questions relating to SQC and calls for some changes. This book covers SQC in a way that conforms with the need to minimize loss. Subjects often not covered elsewhere include: (i) measurements, (ii) determining how many points to sample to obtain reliable control charts (for which purpose a new graphic tool, diffidence charts, is introduced), (iii) the connection between process capability and tolerances, (iv)

  18. HPLC for quality control of polyimides

    Science.gov (United States)

    Young, P. R.; Sykes, G. F.

    1979-01-01

    High Pressure Liquid Chromatography (HPLC) as a quality control tool for polyimide resins and prepregs are presented. A data base to help establish accept/reject criteria for these materials was developed. This work is intended to supplement, not replace, standard quality control tests normally conducted on incoming resins and prepregs. To help achieve these objectives, the HPLC separation of LARC-160 polyimide precursor resin was characterized. Room temperature resin aging effects were studied. Graphite reinforced composites made from fresh and aged resin were fabricated and tested to determine if changes observed by HPLC were significant.

  19. Role of dosimetry in quality control

    International Nuclear Information System (INIS)

    Dosimetry plays an important role in the quality control of radiation processing. Increasingly, quality control systems are based on the standards in the 9000 series from the International Organization for Standardization, ISO. This is true not only in radiation sterilization but also in food treatment, polymer modification and other uses of radiation. It is required that all measurements - including radiation measurements -are traceable to national standards, and the uncertainty of the measurements must be stated with appropriate confidence limits. The paper discusses the significance of dosimetry, the evaluation of uncertainty, and the way in which traceability may be obtained. (author). 11 refs, 2 tabs

  20. Quality Control of Reference Standard Source Production

    International Nuclear Information System (INIS)

    Full text: The preparation techniques of sealed I-131 sources for calibrating gamma ray spectrometry were developed by gravimetric dispensing the reference I-131 solution. Following the production techniques and quality control according to IAEA-TECDOC-1512, four methods including wipe test, impact test, leakage and homogeneity test were employed to demonstrate sealed radioactive sources. The half-life was determined by imaging plate system and found to be 8.10 ± 0.02 days in agreement with the decay theory. The techniques may be useful for quality control of reference standard source production

  1. Biopsy with the New Essen Biopsy Forceps

    Directory of Open Access Journals (Sweden)

    Peter G. Traine

    2013-01-01

    Full Text Available Purpose. To present initial experience with a novel biopsy method, the Essen biopsy forceps. Therefore, two patients with diagnostic suspicion of uveal melanoma underwent biopsy for histopathological confirmation. Case Presentation. Two patients presented with painless unilateral vision reduction. Ultrasound revealed the diagnostic suspicion of uveal melanoma. Therefore, biopsy with the Essen biopsy forceps using a sutureless 23-gauge three-port vitrectomy system was performed. The specimens were then submitted to a pathologist and processed. Histopathology of the obtained specimen confirmed the diagnostic suspicion of choroid melanoma in both patients. Conclusion. Essen biopsy forceps is a very practicable alternative method to the FNAB, allowing a combined histopathological and immunohistochemical examination for achieving high diagnostic accuracy at minimal risk.

  2. Control cards as a statistical quality control resource

    Directory of Open Access Journals (Sweden)

    Aleksandar Živan Drenovac

    2013-02-01

    Full Text Available Normal 0 false false false MicrosoftInternetExplorer4 This paper proves that applying of statistical methods can significantly contribute increasing of products and services quality, as well as increasing of institutions rating. Determining of optimal, apropos anticipatory and limitary values, is based on sample`s statistical analyze. Control cards represent very confident instrument, which is simple for use and efficient for control of process, by which process is maintained in set borders. Thus, control cards can be applied in quality control of procesess of weapons and military equipment production, maintenance of technical systems, as well as for seting of standards and increasing of quality level for many other activities.

  3. Outsourcing University Degrees: Implications for Quality Control

    Science.gov (United States)

    Edwards, Julie; Crosling, Glenda; Edwards, Ron

    2010-01-01

    Education institutions worldwide have and continue to seek opportunities to spread their offerings abroad. While the provision of courses to students located overseas through partner institutions has many advantages, it raises questions about quality control that are not as applicable to other forms of international education. This paper uses a…

  4. Guidelines for radriopharmaceutical quality control in hospitals

    International Nuclear Information System (INIS)

    This document has been prepared to assist hospital administrators in ensuring that adequate quality control is performed on radiopharmaceuticals administered to their patients. Three sets of guidelines are presented, the degree of sophistication being dependent on the amount of hospital involvement in the radiopharmaceutical preparation

  5. Water quality control program in experimental circuits

    International Nuclear Information System (INIS)

    The Water Quality Control Program of the Experimental Circuits visualizes studying the water chemistry of the cooling in the primary and secondary circuits, monitoring the corrosion of the systems and studying the mechanism of the corrosion products transport in the systems. (author)

  6. Quality Control Of Selected Pesticides With GC

    International Nuclear Information System (INIS)

    The practical quality control of selected pesticides with GC is treated. Detailed descriptions are given on materials and methods used, including sample preparation and GC operating conditions. The systematic validation of multi methods is described, comprising performance characteristics in routine analysis, like selectivity, specificity etc. This is illustrated by chromatograms, calibration curves and tables derived from real laboratory data. (author)

  7. Materials, methods and quality control, ch. 3

    International Nuclear Information System (INIS)

    A description of the chemical reagents, the 125I-labelled angiotensin I, the antiserum and the standards is given. A modified measuring method with the New England Nuclear kit for angiotensin I radioimmunoassay is presented as well as the quality control data

  8. Statistical quality control through overall vibration analysis

    Science.gov (United States)

    Carnero, M. a. Carmen; González-Palma, Rafael; Almorza, David; Mayorga, Pedro; López-Escobar, Carlos

    2010-05-01

    The present study introduces the concept of statistical quality control in automotive wheel bearings manufacturing processes. Defects on products under analysis can have a direct influence on passengers' safety and comfort. At present, the use of vibration analysis on machine tools for quality control purposes is not very extensive in manufacturing facilities. Noise and vibration are common quality problems in bearings. These failure modes likely occur under certain operating conditions and do not require high vibration amplitudes but relate to certain vibration frequencies. The vibration frequencies are affected by the type of surface problems (chattering) of ball races that are generated through grinding processes. The purpose of this paper is to identify grinding process variables that affect the quality of bearings by using statistical principles in the field of machine tools. In addition, an evaluation of the quality results of the finished parts under different combinations of process variables is assessed. This paper intends to establish the foundations to predict the quality of the products through the analysis of self-induced vibrations during the contact between the grinding wheel and the parts. To achieve this goal, the overall self-induced vibration readings under different combinations of process variables are analysed using statistical tools. The analysis of data and design of experiments follows a classical approach, considering all potential interactions between variables. The analysis of data is conducted through analysis of variance (ANOVA) for data sets that meet normality and homoscedasticity criteria. This paper utilizes different statistical tools to support the conclusions such as chi squared, Shapiro-Wilks, symmetry, Kurtosis, Cochran, Hartlett, and Hartley and Krushal-Wallis. The analysis presented is the starting point to extend the use of predictive techniques (vibration analysis) for quality control. This paper demonstrates the existence

  9. The role and relevance of quality assurance to quality control

    International Nuclear Information System (INIS)

    The paper describes the development of Quality Assurance as a total management technique, incorporating manufacturing and construction Quality Control, to give confidence of satisfactory in-service performance. The application of QA to the Heysham 2 and Torness AGR projects design and construction is defined with particular reference to the development of a QA requirements specification, delegation of QA responsibility through the hierarchy of purchasers and suppliers of plant and material, the role of the QA organization and QA auditing. The paper discusses the effectiveness and benefits of QA and the problems identified in its application and implementation. The problems, their solutions and longer term improvements to reduce the costs of QA as well as enhancing confidence in the satisfactory performance of future nuclear projects, are described. (author)

  10. Swab or biopsy samples for bioburden testing of allograft musculoskeletal tissue?

    Science.gov (United States)

    Varettas, Kerry

    2014-12-01

    Swab and biopsy samples of allograft musculoskeletal tissue are most commonly collected by tissue banks for bacterial and fungal bioburden testing. An in vitro study was performed using the National Committee for Clinical Laboratory Standards standard 'Quality control of microbiological transport systems' (2003) to validate and evaluate the recovery of six challenge organisms from swab and biopsy samples of allograft musculoskeletal tissue. On average, 8.4 to >100 and 7.2 to >100 % of the inoculum was recovered from swab and biopsy samples respectively. A retrospective review of donor episodes was also performed, consisting of paired swab and biopsy samples received in this laboratory during the period 2001-2012. Samples of allograft femoral heads were collected from living donors during hip operations. From the 3,859 donor episodes received, 21 paired swab and biopsy samples each recovered an isolate, 247 swab samples only and 79 biopsy samples only were culture positive. Low numbers of challenge organisms were recovered from inoculated swab and biopsy samples in the in vitro study and validated their use for bioburden testing of allograft musculoskeletal tissue. Skin commensals were the most common group of organisms isolated during a 12-year retrospective review of paired swab and biopsy samples from living donor allograft femoral heads. Paired swab and biopsy samples are a suitable representative sample of allograft musculoskeletal tissue for bioburden testing. PMID:24599706

  11. 42 CFR 84.41 - Quality control plans; contents.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Quality control plans; contents. 84.41 Section 84... AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.41 Quality control plans; contents. (a) Each quality control plan shall contain provisions for...

  12. Adaptive quality control for multimedia communications

    OpenAIRE

    Santichai Chuaywong; Sinchai Kamolphiwong; Thossaporn Kamolphiwong; Kevin Robert Elz; Suthon Sae-Wong

    2008-01-01

    Multimedia communications are communications with several types of media, such as audio, video and data. The current Internet has some levels of capability to support multimedia communications, unfortunately, the QoS (Quality of Service) is still challenging. A large number of QoS mechanisms has been proposed; however, the main concern is for low levels, e.g. layer 2 (Data Link) or 3 (Transport). In this paper, mechanisms for control the quality of audio and video are proposed. G.723.1 and MP...

  13. Quality and Control of Water Vapor Winds

    Science.gov (United States)

    Jedlovec, Gary J.; Atkinson, Robert J.

    1996-01-01

    Water vapor imagery from the geostationary satellites such as GOES, Meteosat, and GMS provides synoptic views of dynamical events on a continual basis. Because the imagery represents a non-linear combination of mid- and upper-tropospheric thermodynamic parameters (three-dimensional variations in temperature and humidity), video loops of these image products provide enlightening views of regional flow fields, the movement of tropical and extratropical storm systems, the transfer of moisture between hemispheres and from the tropics to the mid- latitudes, and the dominance of high pressure systems over particular regions of the Earth. Despite the obvious larger scale features, the water vapor imagery contains significant image variability down to the single 8 km GOES pixel. These features can be quantitatively identified and tracked from one time to the next using various image processing techniques. Merrill et al. (1991), Hayden and Schmidt (1992), and Laurent (1993) have documented the operational procedures and capabilities of NOAA and ESOC to produce cloud and water vapor winds. These techniques employ standard correlation and template matching approaches to wind tracking and use qualitative and quantitative procedures to eliminate bad wind vectors from the wind data set. Techniques have also been developed to improve the quality of the operational winds though robust editing procedures (Hayden and Veldon 1991). These quality and control approaches have limitations, are often subjective, and constrain wind variability to be consistent with model derived wind fields. This paper describes research focused on the refinement of objective quality and control parameters for water vapor wind vector data sets. New quality and control measures are developed and employed to provide a more robust wind data set for climate analysis, data assimilation studies, as well as operational weather forecasting. The parameters are applicable to cloud-tracked winds as well with minor

  14. Determination and evaluation of air quality control. Manual of ambient air quality control in Germany

    Energy Technology Data Exchange (ETDEWEB)

    Lahmann, E.

    1997-07-01

    Measurement of air pollution emissions and ambient air quality are essential instruments for air quality control. By undertaking such measurements, pollutants are registered both at their place of origin and at the place where they may have an effect on people or the environment. Both types of measurement complement each other and are essential for the implementation of air quality legislation, particularly, in compliance with emission and ambient air quality limit values. Presented here are similar accounts of measurement principles and also contains as an Appendix a list of suitability-tested measuring devices which is based on information provided by the manufacturers. In addition, the guide of ambient air quality control contains further information on discontinuous measurement methods, on measurement planning and on the assessment of ambient air quality data. (orig./SR)

  15. Laboratory quality control based on risk management.

    Science.gov (United States)

    Nichols, James H

    2011-01-01

    Risk management is the systematic application of management policies, procedures, and practices to the tasks of analyzing, evaluating, controlling and monitoring risk (the effect of uncertainty on objectives). Clinical laboratories conduct a number of activities that could be considered risk management including verification of performance of new tests, troubleshooting instrument problems and responding to physician complaints. Development of a quality control plan for a laboratory test requires a process map of the testing process with consideration for weak steps in the preanalytic, analytic and postanalytic phases of testing where there is an increased probability of errors. Control processes that either prevent or improve the detection of errors can be implemented at these weak points in the testing process to enhance the overall quality of the test result. This manuscript is based on a presentation at the 2nd International Symposium on Point of Care Testing held at King Faisal Specialist Hospital in Riyadh, Saudi Arabia on October 12-13, 2010. Risk management principles will be reviewed and progress towards adopting a new Clinical and Laboratory Standards Institute Guideline for developing laboratory quality control plans based on risk management will be discussed. PMID:21623049

  16. Laboratory quality control based on risk management

    Directory of Open Access Journals (Sweden)

    Nichols James

    2011-01-01

    Full Text Available Risk management is the systematic application of management policies, procedures, and practices to the tasks of analyzing, evaluating, controlling and monitoring risk (the effect of uncertainty on objectives. Clinical laboratories conduct a number of activities that could be considered risk management including verification of performance of new tests, troubleshooting instrument problems and responding to physician complaints. Development of a quality control plan for a laboratory test requires a process map of the testing process with consideration for weak steps in the preanalytic, analytic and postanalytic phases of testing where there is an increased probability of errors. Control processes that either prevent or improve the detection of errors can be implemented at these weak points in the testing process to enhance the overall quality of the test result. This manuscript is based on a presentation at the 2nd International Symposium on Point of Care Testing held at King Faisal Specialist Hospital in Riyadh, Saudi Arabia on October 12-13, 2010. Risk management principles will be reviewed and progress towards adopting a new Clinical and Laboratory Standards Institute Guideline for developing laboratory quality control plans based on risk management will be discussed.

  17. Bone marrow biopsy

    Science.gov (United States)

    Biopsy - bone marrow ... A bone marrow biopsy may be done in the health care provider's office or in a hospital. The sample may be taken from the pelvic or breast bone. Sometimes, other areas are used. Marrow is removed ...

  18. Mediastinoscopy with biopsy

    Science.gov (United States)

    ... medlineplus.gov/ency/article/003864.htm Mediastinoscopy with biopsy To use the sharing features on this page, please enable JavaScript. Mediastinoscopy with biopsy is a procedure in which a lighted instrument ( ...

  19. Sentinel Lymph Node Biopsy

    Science.gov (United States)

    ... Ask about Your Diagnosis Research Sentinel Lymph Node Biopsy On This Page What are lymph nodes? What ... lymph node? What is a sentinel lymph node biopsy? What happens during an SLNB? What are the ...

  20. Nerve biopsy (image)

    Science.gov (United States)

    Nerve biopsy is the removal of a small piece of nerve for examination. Through a small incision, a sample ... is removed and examined under a microscope. Nerve biopsy may be performed to identify nerve degeneration, identify ...

  1. Sentinel node biopsy (image)

    Science.gov (United States)

    Sentinel node biopsy is a technique which helps determine if a cancer has spread (metastasized), or is contained locally. When a ... is closest to the cancer site. Sentinel node biopsy is used to stage many kinds of cancer, ...

  2. Cold knife cone biopsy

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/003910.htm Cold knife cone biopsy To use the sharing features on this page, please enable JavaScript. A cold knife cone biopsy (conization) is surgery to remove ...

  3. Protein quality control in the nucleus.

    Science.gov (United States)

    Jones, Ramon D; Gardner, Richard G

    2016-06-01

    The nucleus is the repository for the eukaryotic cell's genetic blueprint, which must be protected from harm to ensure survival. Multiple quality control (QC) pathways operate in the nucleus to maintain the integrity of the DNA, the fidelity of the DNA code during replication, its transcription into mRNA, and the functional structure of the proteins that are required for DNA maintenance, mRNA transcription, and other important nuclear processes. Although we understand a great deal about DNA and RNA QC mechanisms, we know far less about nuclear protein quality control (PQC) mechanisms despite that fact that many human diseases are causally linked to protein misfolding in the nucleus. In this review, we discuss what is known about nuclear PQC and we highlight new questions that have emerged from recent developments in nuclear PQC studies. PMID:27015023

  4. Quality control of nuclear medicine equipment

    International Nuclear Information System (INIS)

    In order to determine functional status and integrity of installations and equipment used in nuclear medicine in everyday medical practice or in research studies, it is important to maintain and implement quality control program. For this type of installation are required high standards, particularly with regard to qualitative and quantitative analysis of the image, and volume measurements in diagnosis and dosimetry. Given the precarious situation of the economy in transition, nuclear medicine departments in the republic, now, can not be always of service contracts with providers of facilities and equipment for routine maintenance and periodic calibration. Therefore, in this article are at some of the quality control procedures should be performed usually by engineers and physicists from the department of nuclear medicine. (authors)

  5. Quality Control in Dental Radiology in Greece

    International Nuclear Information System (INIS)

    Quality control was implemented in 52 dental intra-oral X ray units in use in the public and private sector in Hellas. The protocol consisted of visual inspection of the X ray unit, complete registration of the unit's characteristics, measurement of the unit's radiological parameters, inspection of the radiation protection facilities for patient and personnel and examination of film processing conditions. The results are characterised by the large number of old X ray units, the great variability in entrance surface doses and linearity of output and the absence of strict patient and operator radiation protection measures. Analogue exposure timers have very poor accuracy compared to digital ones. Imaging techniques and film processing do not always comply with standards among dentists. In view of the above, the implementation of a Quality Control programme, including reference doses, which could, for example, be selected according to the results of this paper, is strongly recommended in Dental Radiology in Hellas. (author)

  6. Progress in gamma-camera quality control

    International Nuclear Information System (INIS)

    The latest developments in the art of quality control of gamma cameras are emphasized in a simple historical manner. The exhibit describes methods developed by the Bureau of Radiological Health (BRH) in comparison with previously accepted techniques for routine evaluation of gamma-camera performance. Gamma cameras require periodic testing of their performance parameters to ensure that their optimum imaging capability is maintained. Quality control parameters reviewed are field uniformity, spatial distortion, intrinsic and spatial resolution, and temporal resolution. The methods developed for the measurement of these parameters are simple, not requiring additional electronic equipment or computers. The data has been arranged in six panels as follows: schematic diagrams of the most important test patterns used in nuclear medicine; field uniformity; regional displacements in transmission pattern image; spatial resolution using the BRH line-source phantom; instrinsic resolution using the BRH Test Pattern; and Temporal resolution and count losses at high counting rates

  7. AQCS: Analytical Quality Control Services intercomparison runs

    International Nuclear Information System (INIS)

    This document describes an interlaboratory comparison exercise run by the IAEA and includes description of the intercomparison material, scope of the study, quality control requirements and reporting requirements including reporting forms and questionnaires. The intercomparison material is homogenized soil and participants are requested using their established and proven analytical techniques to measure six radioisotopes: K-40, Sr-90, Cs-134, Cs-137, and Pu-239. The document also contains the results obtained and their interpretation

  8. The software quality control for gamma spectrometry

    International Nuclear Information System (INIS)

    One of major problems with wich the quality control program of an environmental measurements laboratory is confronted is the evaluation of the performances of software packages for the analysis of gamma-ray spectra. A program of tests for evaluating the performances of the software package (SPECTRAN-F, Canberra Inc.) used by our laboratory is being carried out. In this first paper the results of a preliminary study concerning the evaluation of the performance of the doublet analysis routine are presented

  9. Quality control in the year 2000

    OpenAIRE

    Schade, Bernd

    1992-01-01

    ‘Just-in-time’ production is a prerequisite for a company to meet the challenges of competition. Manufacturing cycles have been so successfully optimized that release time now has become a significant factor. A vision for a major quality-control (QC) contribution to profitability in this decade seems to be the just-in-time release. Benefits will go beyond cost savings for lower inventory. The earlier detection of problems will reduce rejections and scrap. In addition, problem analysis and pro...

  10. Applying GPS to check horizontal control quality

    OpenAIRE

    Jakub Vincent; Weiss Gabriel; Sabová Jana

    2004-01-01

    GPS technologies can also be used for check quality in available horizontal point set with coordinates CJ of the frame S-JTSK. When survey and setting-out tasks should be performed in certain area, one can found in it allways some points of the fundamental and detail state controls. To use these points for some actual aims, it is necessary to investigate their compatibility (among the point mark positions and the point coordinate of control points). This can be done using GPS surveying that m...

  11. Glycoprotein Quality Control and Endoplasmic Reticulum Stress

    Directory of Open Access Journals (Sweden)

    Qian Wang

    2015-07-01

    Full Text Available The endoplasmic reticulum (ER supports many cellular processes and performs diverse functions, including protein synthesis, translocation across the membrane, integration into the membrane, folding, and posttranslational modifications including N-linked glycosylation; and regulation of Ca2+ homeostasis. In mammalian systems, the majority of proteins synthesized by the rough ER have N-linked glycans critical for protein maturation. The N-linked glycan is used as a quality control signal in the secretory protein pathway. A series of chaperones, folding enzymes, glucosidases, and carbohydrate transferases support glycoprotein synthesis and processing. Perturbation of ER-associated functions such as disturbed ER glycoprotein quality control, protein glycosylation and protein folding results in activation of an ER stress coping response. Collectively this ER stress coping response is termed the unfolded protein response (UPR, and occurs through the activation of complex cytoplasmic and nuclear signaling pathways. Cellular and ER homeostasis depends on balanced activity of the ER protein folding, quality control, and degradation pathways; as well as management of the ER stress coping response.

  12. 7 CFR 58.335 - Quality control tests.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Quality control tests. 58.335 Section 58.335... Procedures § 58.335 Quality control tests. All milk, cream and related products are subject to inspection for quality and condition throughout each processing operation. Quality control tests shall be made on...

  13. Quality assurance and control, simply a must

    International Nuclear Information System (INIS)

    Full text: At the low level tritium laboratory Arsenal the work with isotopes started in the 1960s. At that time quality control or assurance were words not used very frequently or simply not known and until the 1980s this situation did not change. But running a laboratory without any control or working directions does not make sense as customers who received doubtful results can not be expected to submit further samples for analyses to that institute. At the time before a controlled quality assurance system was established and before ACCESS or ORACLE appeared a database was programmed to host all relevant sample data. All samples run through the preparation steps identified by a unique sample number assigned by the database program during the registration process. The liquid scintillation counters were attached to a mainframe computer with the help of which the final calculations were done. Lists of background and efficiency values were and still are updated after each calculation in the form of control charts and deviations from expected system characteristics are easily visible. In the year 1993 the research centre applied for the certification according to ISO 9001. In the course of this process a quality management handbook containing information about the department's activities and personal structure and the responsibilities as well. In a series of working instructions all procedures were documented and the persons in charge had to approve he knowledge about these instruction by their signature. In 1996 the centre was certified. After the certification audit regular internal audit were and are performed to guarantee the quality of the results leaving our laboratory. In a next step the centre applied for accreditation and in 1998 the accreditation was granted by the ministry responsible. In 2003 we passed the first reaudit with success. An important part of quality control plays a laboratory intercomparison. As part of our quality management system we

  14. Analysis of biopsy outcome after three-dimensional conformal radiation therapy of prostate cancer using dose-distribution variables and tumor control probability models

    International Nuclear Information System (INIS)

    Purpose: To investigate tumor control following three-dimensional conformal radiation therapy (3D-CRT) of prostate cancer and to identify dose-distribution variables that correlate with local control assessed through posttreatment prostate biopsies. Methods and Material: Data from 132 patients, treated at Memorial Sloan-Kettering Cancer Center (MSKCC), who had a prostate biopsy 2.5 years or more after 3D-CRT for T1c-T3 prostate cancer with prescription doses of 64.8-81 Gy were analyzed. Variables derived from the dose distribution in the PTV included: minimum dose (Dmin), maximum dose (Dmax), mean dose (Dmean), dose to n% of the PTV (Dn), where n = 1%, ..., 99%. The concept of the equivalent uniform dose (EUD) was evaluated for different values of the surviving fraction at 2 Gy (SF2). Four tumor control probability (TCP) models (one phenomenologic model using a logistic function and three Poisson cell kill models) were investigated using two sets of input parameters, one for low and one for high T-stage tumors. Application of both sets to all patients was also investigated. In addition, several tumor-related prognostic variables were examined (including T-stage, Gleason score). Univariate and multivariate logistic regression analyses were performed. The ability of the logistic regression models (univariate and multivariate) to predict the biopsy result correctly was tested by performing cross-validation analyses and evaluating the results in terms of receiver operating characteristic (ROC) curves. Results: In univariate analysis, prescription dose (Dprescr), Dmax, Dmean, dose to n% of the PTV with n of 70% or less correlate with outcome (p 2: EUD correlates significantly with outcome for SF2 of 0.4 or more, but not for lower SF2 values. Using either of the two input parameters sets, all TCP models correlate with outcome (p 2, is limited because the low dose region may not coincide with the tumor location. Instead, for MSKCC prostate cancer patients with their

  15. The IAEA's programme on analytical quality control

    International Nuclear Information System (INIS)

    In the early 1960s, the IAEA decided to launch a programme for the assessment of the reliability of low level radiochemical analysis and since then, the Analytical Quality Control Services (AQCS) has developed into a major organiser of world-wide intercomparison runs. Over the intervening years, the types of matrices studied and the analytes of interest have been extended beyond the limits of radioactivity measurements to encompass: trace elements, organic contaminants, stable isotopes and methyl mercury. The Agency provides assistance to its Member States through the AQCS programme to improve the standard of analytical results in their laboratories. These results must be of a certain quality (i.e. accuracy and precision) which is determined by their intended use and should be comparable with other analytical measurements produced elsewhere. In order to enable laboratories in Member States to generate analytical measurements with appropriate and internationally recognised quality the main objectives of AQCS programme are: to provide the analyst with tools to compare and evaluate their performance relative to other laboratories, to assess the accuracy and precision of the analytical method used, to provide objective evidence on the quality of the results, and to ensure comparable analytical results within projects and networks

  16. Percutaneous renal biopsy specimens in stone formers.

    OpenAIRE

    Harrison, D.J.; Inglis, J A; Tolley, D. A.

    1988-01-01

    A series of renal biopsy specimens taken at the time of percutaneous nephrolithotomy were investigated for the presence and location of foci of microcalcification. Calcium was found in 18 of 25 (72%) of biopsy specimens from stone formers and in only seven of 30 (23%) of control biopsy specimens. This may indicate defective intrarenal handling of calcium as plasma calcium concentration was normal and 40% had a raised 24 hour urinary calcium excretion.

  17. Adaptive quality control for multimedia communications

    Directory of Open Access Journals (Sweden)

    Santichai Chuaywong

    2008-01-01

    Full Text Available Multimedia communications are communications with several types of media, such as audio, video and data. The current Internet has some levels of capability to support multimedia communications, unfortunately, the QoS (Quality of Service is still challenging. A large number of QoS mechanisms has been proposed; however, the main concern is for low levels, e.g. layer 2 (Data Link or 3 (Transport. In this paper, mechanisms for control the quality of audio and video are proposed. G.723.1 and MPEG-4 are used as the audio and video codec respectively. The proposed algorithm for adaptive quality control of audio communication is based on forward error correction (FEC. In the case of video communication, the proposed algorithm adapts the value of key frame interval, which is an encoding parameter of MPEG-4. We evaluated our proposed algorithms by computer simulation. We have shown that, in most cases, the proposed scheme gained a higher throughput compared to other schemes.

  18. Optimization and quality control of computed radiography

    Science.gov (United States)

    Willis, Charles E.; Weiser, John C.; Leckie, Robert G.; Romlein, John R.; Norton, Gary S.

    1994-05-01

    Computed radiography (CR) is a relatively new technique for projection radiography. Few hospitals have CR devices in routine service and only a handful have more than one CR unit. As such, the clinical knowledge base does not yet exist to establish quality control (QC) procedures for CR devices. Without assurance that CR systems are operating within nominal limits, efforts to optimize CR performance are limited in value. A complete CR system includes detector plates that vary in response, cassettes, an electro-optical system for developing the image, computer algorithms for processing the raw image, and a hard copy output device. All of these subsystems are subject to variations in performance that can degrade image quality. Using CR manufacturer documentation, we have defined acceptance protocols for two different Fuji CR devices, the FCR 7000 and the AC1+, and have applied these tests to ten individual machines. We have begun to establish baseline performance measures and to determine measurement frequencies. CR QC is only one component of the overall quality control for totally digital radiology departments.

  19. Quality Management of CERN Vacuum Controls

    CERN Document Server

    Antoniotti, F; Fortescue-Beck, E; Gama, J; Gomes, P; Le Roux, P; Pereira, H; Pigny, G

    2014-01-01

    The vacuum controls Section (TE-VSC-ICM) is in charge of the monitoring, maintenance and consolidation of the control systems of all accelerators and detectors in CERN; this represents 6 000 instruments distributed along 128 km of vacuum chambers, often of heterogeneous architectures and of diverse technical generations. In order to improve the efficiency of the services provided by ICM, to vacuum experts and to accelerator operators, a Quality Management Plan is being put into place. The first step was the standardization of the naming convention across different accelerators. The traceability of problems, requests, repairs, and other actions, has also been put into place (VTL). This was combined with the effort to identify each individual device by a coded label, and register it in a central database (MTF). Occurring in parallel, was the gathering of old documents and the centralization of information concerning architectures, procedures, equipment and settings (EDMS). To describe the topology of control c...

  20. Quality control in the year 2000.

    Science.gov (United States)

    Schade, B

    1992-01-01

    'Just-in-time' production is a prerequisite for a company to meet the challenges of competition. Manufacturing cycles have been so successfully optimized that release time now has become a significant factor. A vision for a major quality-control (QC) contribution to profitability in this decade seems to be the just-in-time release. Benefits will go beyond cost savings for lower inventory. The earlier detection of problems will reduce rejections and scrap. In addition, problem analysis and problem-solving will be easier. To achieve just-in-time release, advanced automated systems like robots will become the workhorses in QC for high volume pharmaceutical production. The requirements for these systems are extremely high in terms of quality, reliability and ruggedness. Crucial for the success might be advances in use of microelectronics for error checks, system recording, trouble shooting, etc. as well as creative new approaches (for example the use of redundant assay systems). PMID:18924930

  1. Progress in quality control of alanine dosimeters

    International Nuclear Information System (INIS)

    The ESR/alanine system has been used for different applications, over several years, as a classical routine dosimetry service. This service is based on alanine dosimeters constituted by pellets manufactured by our laboratory, which are presented with some specifications of use and different parameters bound to the intrinsic quality of the dosimeter itself. These parameters were obtained through the strict application of a production protocol and a validation protocol created, tested and validated under a quality assurance system. Every year, one batch of photon dosimeters is produced and controlled using these protocols and the specifications associated with it are checked. Two categories of data are considered separately: physical parameters and experimental data obtained by measurement on our ESR system are given with their associated standard deviation. (author)

  2. Microbiological quality control practices at Australian Radioisotopes

    International Nuclear Information System (INIS)

    As a domestic manufacturer of therapeutic substances, Australian Radioisotopes (ARI) must adhere to guidelines set out by the Commonwealth Department of Health in the Code of Good Manufacturing Practices for Therapeutic Goods 1983 (GMP). The GMP gives guidelines for staff training, building requirements, sanitation, documentation and quality control practices. These guidelines form the basis for regular audits performed by officers of the National Biological Standards Laboratories. At Lucas Heights, ARI has combined the principles of the GMP with the overriding precautions introduced for environmental and staff safety and protection. Its policy is to maintain a high level of quality assurance for product identity, purity and sterility and apyrogenicity during all stages of product manufacture

  3. Radar data quality control methods in VOLTAIRE

    Energy Technology Data Exchange (ETDEWEB)

    Golz, C.; Einfalt, T. [einfalt und hydrotec GbR, Luebeck (Germany); Galli, G. [MeteoSvizzera, Locarno-Monti (Switzerland)

    2006-10-15

    In the scope of the EU-project VOLTAIRE (Validation of multisensors precipitation fields and numerical modelling in Mediterranean test sites) a software library for automatic and rapid radar data quality check and modification has been developed and tests have been performed with data from different countries. Automatic procedures will never replace an experienced observer, but they help him to do his work and they can be used at places, where observation is not possible.This paper gives an overview over the algorithms that have been adopted or developed during the VOLTAIRE project for radar data quality control. Two examples of these algorithms illustrate the possibilities for data correction but also their limitations. These examples are a clutter correction combined with speckle removal for plan position indicator (PPI) data in particular of non-Doppler radars and a beam blockage correction for PPI data, where no digital elevation model (DEM) is available. (orig.)

  4. Needle Biopsy of the Lung

    Science.gov (United States)

    ... Physician Resources Professions Site Index A-Z Needle Biopsy of the Lung Needle biopsy of the lung ... Needle Biopsy of Lung Nodules? What is Needle Biopsy of the Lung? A lung nodule is relatively ...

  5. Ultrasound-Guided Breast Biopsy

    Science.gov (United States)

    ... Professions Site Index A-Z Ultrasound-Guided Breast Biopsy An ultrasound-guided breast biopsy uses sound waves ... Guided Breast Biopsy? What is Ultrasound-Guided Breast Biopsy? Lumps or abnormalities in the breast are often ...

  6. Stereotactic (Mammographically Guided) Breast Biopsy

    Science.gov (United States)

    ... Resources Professions Site Index A-Z Stereotactic Breast Biopsy Stereotactic breast biopsy uses mammography – a specific type ... Breast Biopsy? What is Stereotactic (Mammographically Guided) Breast Biopsy? Lumps or abnormalities in the breast are often ...

  7. Quality control of krypton-81m generator

    Energy Technology Data Exchange (ETDEWEB)

    Comet, M.; Croize, J.; Gaudy, M.; Mathieu, J.P.; Pernin, C.; Dubois, F.; Verain, A. (C.H.R.U., Grenoble (France)); Godart, J.; Boutet, J. (Institut des Sciences Nucleaires, Grenoble (France))

    1982-01-01

    The control of quality of the short half life radiopharmaceutical krypton-81m in solution is detailed. Because it is not possible to test sterility, to measure the pH and the activity of the contaminants and to search pyrogen in the solution which will be injected, a compromise must be done. If the characteristics of the eluat of the generator (pH, activity of the contaminants) are stable and in acceptable limits during 3 hours, the perfusion must be done with an acceptable risk. The apyrogenicity of the eluat must be tested with the rabbit pyrogen test and with the L.A.L. before injection. The control of sterility must be done though the results are obtained long after the perfusion.

  8. Quality control of krypton-81m generator

    International Nuclear Information System (INIS)

    The control of quality of the short half life radiopharmaceutical krypton-81m in solution is detailed. Because it is not possible to test sterility, to measure the pH and the activity of the contaminants and to search pyrogen in the solution which will be injected, a compromise must be done. If the characteristics of the eluat of the generator (pH, activity of the contaminants) are stable and in acceptable limits during 3 hours, the perfusion must be done with an acceptable risk. The apyrogenicity of the eluat must be tested with the rabbit pyrogen test and with the L.A.L. before injection. The control of sterility must be done though the results are obtained long after the perfusion

  9. 7 CFR 58.141 - Alternate quality control program.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Alternate quality control program. 58.141 Section 58... Service 1 Quality Specifications for Raw Milk § 58.141 Alternate quality control program. When a plant has in operation an acceptable quality program, at the producer level, which is approved by...

  10. Indoor air quality control; Sisaeilman laadun hallinta

    Energy Technology Data Exchange (ETDEWEB)

    Villberg, K.; Saarela, K.; Tirkkonen, T. [VTT Building and Transport, Espoo (FI)] [and others

    2004-06-01

    Indoor Air Quality Control-project (Dno 188/401/00, 40724/00), one part of the Finnish Research Programme on Environmental Health (SYTTY), was consisted of three parts. In part one the objective was to establish a causal connection between indoor air quality, perceived comfort and diagnosed health effects. The indoor air quality was measured with methods used today in the Finnish classification, but complementary new methods were applied and tested for their relevance in attaining a better coverage of different chemical substances in indoor air. The health and comprehensive indoor air data were collected from subjects, which were chosen among the patients treated in Helsinki University Central Hospital because of building related symptoms. Additionally control families were randomly selected from Helsinki area. All participants were interviewed for their residential conditions and any building related problems using modified Oerebro and Tuohilampi questionnaires. Clinical data was only collected from the patients in medical examination. All these data was used as additional information in drafting conclusions and recommendations for the improvement of characterising indoor air quality and the classification procedure. In the second part the aim was to develop procedures to evaluate the irritating and odorous chemical compounds of material emissions and the perceived air quality. The causative relationships between sensory assessment method used in the present Finnish Classification of Building Materials, olfactometry and emission measurements in chemical terms were determined. Another objective of this project was to investigate irritation properties of building material emissions and chemical mixtures by the mouse bioassay. In addition the indicator value of human evaluation was clarified for estimating irritancy of building material emission and for studying an impact of ageing of materials on odour and irritation responses. Finally a model was developed for

  11. Quality Control, Quality Assurance, and Quality Improvement-What is the Difference and Why Should Compounding Pharmacies Care?

    Science.gov (United States)

    Cabaleiro, Joe

    2009-01-01

    This article provides scenarios of three different pharmacies in the areas of quality control, quality assurance, and quality improvement. The scenarios show the importance that each pharmacy placed on a problem of dented capsules and the potential impact that an unresolved problem can have on a compounding pharmacy's business. Although this article focuses on one particular procedure, the purpose of th article is to help pharmacists understand the differences between quality control, quality assurance, and quality improvement. PMID:23966522

  12. Quality control of radioimmunoassay for proteins

    International Nuclear Information System (INIS)

    The philosophy and achievements of the first two and a half years of a national quality control scheme for serum growth hormone assays are described. Three serum samples were distributed to participating laboratories every two weeks. A computer-produced summary of the quality control results, containing scattergrams and statistical analysis, was returned to participants. The performance of 11 experienced (SAS) laboratories was found to fulfil the necessary accuracy criteria, thus providing the 'reference group mean', and target value. Gross positive bias exhibited by several laboratories was due to the use of assays with inadequate sensitivity, and was promptly eliminated. During the course of the Scheme the average bias fell from 30 to 14%. With assays of adequate sensitivity, bias was almost invariably due to the misuse of standards. Median within-laboratory, between-batch precision (CV) improved from 23 to 15%. The best performers achieved between-batch CV of 7% which was 1.5 x their within-batch CV: the worst had three-to four-fold differences between within- and between-batch CV. A 'recommended procedure' based upon supplied first and second antibody, and a communal 'reference range' from 280 untreated acromegalics, both proved valuable. (author)

  13. Quality control of nuclear medicine instruments

    International Nuclear Information System (INIS)

    This document, which gives detailed guidance on the quality control of the various electronic instruments used for radiation detection and measurement in nuclear medicine, stems from the work of two Advisory Groups convened by the International Atomic Energy Agency (IAEA). A preliminary document, including recommended test schedules but lacking actual protocols for the tests, was drawn up by the first of these groups, meeting at the IAEA Headquarters in Vienna in 1979. A revised and extended version, incorporating recommended test protocols, was prepared by the second Group, meeting likewise in Vienna in 1982. This version is the model for the present text. The document should be of value to all nuclear medicine units, and especially to those in developing countries, in the initiation or revision of schemes for the quality control of their instruments. Its recommendations have provided the basis for instruction in two IAEA regional technical co-operation projects in the subject field, one initiated in 1981 for countries of Latin America and one initiated in 1982 for countries of Asia and the Pacific

  14. Efficacy of video assisted thoracoscopic lung biopsy: an historical comparison with open lung biopsy.

    OpenAIRE

    Carnochan, F. M.; Walker, W. S.; Cameron, E W

    1994-01-01

    BACKGROUND--Video assisted thoracoscopic lung biopsies were compared with historical controls undergoing open lung biopsy to determine the diagnostic accuracy, effect on length of postoperative stay, and cost effectiveness of the new thoracoscopic technique. METHODS--The first 25 video assisted thoracoscopic lung biopsies performed in the Edinburgh Thoracic Unit were compared with 25 historical controls for complications, diagnostic accuracy, and length of postoperative stay. RESULTS--Statist...

  15. Quality assurance and quality control in fabrication of cladding tubes

    International Nuclear Information System (INIS)

    Zircaloy 2 and 4 are the most important Zirconium alloys for use as fuel cladding material in light and heavy water reactors. In fast breeder reactors the cladding tubes are of a modified 16/16 - Cr-Ni-type with improved mechanical, long - term creep rate and rupture - life versus temperature properties. Starting with hot-extruded tube shells the fabrication of Zircaloy cladding tubes is done by 3 - 4 cold reduction steps in tube reducers or rolling machines followed by heat treatments in vacuum. To obtain the specified properties a precise combination of final area reduction and final annealing is absolutely necessary. The fabrication route of stainless steel claddings and guide tubes is similar to the Zircaloy production, exceptionally the last cold-forming steps are made on cold-drawing henches, hecause of economic reasons. After each cold reduction the material is annealed at recrystalisation temperatures under protective atmosoheres. For obtaining the same final tube properties for a longer nroduction neriod the implementation of a quality assurance and control system naturally independent of the production is necessary. The application of this system regarding some of the important properties of fuel cladding tubes is reported. (RW)

  16. Computed tomography quality control (QC) status in Sudan

    International Nuclear Information System (INIS)

    Quality control (QC) tests were performed to eleven computed tomography (CT) scanners in Khartoum, the capital of Sudan. The work was performed as part of the authorization procedure, which was requested on behalf of the Radiation Protection Technical Committee (RPTC), the regulatory authority in Sudan. The purpose of the present study is to address malfunctioning of CT scanners and define its impact on image quality and state to which extent it can affect the diagnostic information gained from undergoing CT scanning. For the sake of achieving a thorough study of this issue, the relevant hospital staff - technologists, radiologists and medical engineers - were involved in this study through discussion and questionnaire. The measurements were performed in accordance with IEC and ImPACT CT quality control protocols. The following tests were involved: average CT number for water, CT number uniformity, noise, high contrast resolution, low contrast resolution, slice thickness, and CT number linearity. All scanners under study were tested, different performance phantoms were used as each manufacturer has its own phantom but all are testing same parameters, however each with its own method, e.g. for spatial resolution some using bar pattern while others using drilled holes, but both reflect the same result when expressed in terms of limited resolution in millimetres. The primary analysis of collected data revealed that more than 60% of scanners under study were installed within the last three years. Nevertheless, the dominant feature among all scanners was the absence of quality assurance and quality control programmes - no acceptance testing is performed upon installation of the equipment, no designated personnel are available for quality control measurements, no preventive maintenance and regular calibration are being conducted. In some units, no performance phantoms were supplied with the scanner, and generally, the importance of quality control is not highly

  17. 14 CFR 145.211 - Quality control system.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Quality control system. 145.211 Section 145...) SCHOOLS AND OTHER CERTIFICATED AGENCIES REPAIR STATIONS Operating Rules § 145.211 Quality control system. (a) A certificated repair station must establish and maintain a quality control system acceptable...

  18. 21 CFR 864.8625 - Hematology quality control mixture.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Hematology quality control mixture. 864.8625 Section 864.8625 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... quality control mixture. (a) Identification. A hematology quality control mixture is a device used...

  19. 7 CFR 275.21 - Quality control review reports.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Quality control review reports. 275.21 Section 275.21... Reporting on Program Performance § 275.21 Quality control review reports. (a) General. Each State agency shall submit reports on the performance of quality control reviews in accordance with the...

  20. 40 CFR 75.21 - Quality assurance and quality control requirements.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Quality assurance and quality control... PROGRAMS (CONTINUED) CONTINUOUS EMISSION MONITORING Operation and Maintenance Requirements § 75.21 Quality assurance and quality control requirements. (a) Continuous emission monitoring systems. The owner...

  1. Quality control for electronic portal imaging devices

    International Nuclear Information System (INIS)

    Full text: The need for objective quality control of electronic portal imaging devices (EPIDs) arises at a number of different stages. The manufacturer should be able to conduct a test before shipping the EPID, to be sure that the device meets predetermined specifications. On installation, the engineer should have a simple and definitive test to ensure that installation is complete. The customer also requires proof that specifications have been met. And a quick and easy test is required for daily or weekly verification that the EPID is operating as well as at installation. All the suppliers of EPIDs provide copies of the 'Las Vegas' phantom, but this is a highly subjective test that was never intended to be used for routine quality control. A quality control test is described which involves acquiring a pair of portal images of a specially designed phantom, followed by totally automatic analysis to provide quantities related to the spatial resolution and the contrast-to-noise ratio. The phantom includes five bar patterns, with spatial frequencies from 0.1 to 0.75 1p/mm. The measured modulation in each pattern is normalized to the value at the lowest frequency, and the spatial frequency f50 corresponding to a 50% decrease in RMIF is used as the measure of spatial resolution. Contrast is measured in regions of the phantom with different attenuations, and noise is obtained from the difference image derived from the original pair. Tests were conducted on EPIDs from all the commercial suppliers. By determining f50 with the phantom placed on the surface of the EPID, and again at isocenter (ISO), it is possible to determine the relative contributions to image blurring from the EPID (E) and from the effect of the finite focal spot size in the linac (S). In all cases the effect of the focal spot is dominant. The results are presented in a table, which shows mean values of the resolution, blurring parameters E and S, the optimal magnification, and the best attainable

  2. US-guided biopsy of renal allografts using 18G biopsy gun: analysis of 200 cases

    International Nuclear Information System (INIS)

    We evaluated the effectiveness and safety of 18G biopsy gun with US guidance in the transplanted kidneys. We performed 200 US-guided percutaneous biopsies using 18G biopsy gun. Diagnostic efficacy and complication of the biopsy in these patients were analyzed. Biopsy specimens were adequate for histologic diagnoses in 193 patients(96.5%). The mean of the biopsy frequency was 3, the mean of total glomerular number was 21.64 and the mean glomerular number per one biopsy was 6.93. Major complications occurred in 3 (1.5%) of the 200 biopsies; hematuria developed in two patients, AV fistula in one. These complications were successfully controlled either by only transfusion or by coil embolization. There were no statistical differences in blood pressure, hemoglobin, BUN/Cr between pre-and post-renal biopsies. US-guided percutaneous biopsy of renal allograft with 18G biopsy gun is simple, safe, and accurate method in evaluating the renal allograft dysfunction

  3. Clinical impact of bladder biopsies with TUR-BT according to cytology results in patients with bladder cancer: a case control study

    Directory of Open Access Journals (Sweden)

    Matsumoto Kazuhiro

    2010-06-01

    Full Text Available Abstract Background There seems to be no consensus concerning taking bladder biopsies during transurethral resection of bladder tumor (TUR-BT. We investigate the clinical significance of bladder biopsy with TUR-BT and the relationship between urinary cytology and the biopsy results. Methods We reviewed a total of 424 patients with non-muscle invasive bladder cancer treated with TUR-BT between 1998 and 2005. Of the total, 293 patients also underwent a bladder biopsy. Biopsies from suspicious-appearing urothelium (N = 59 and those from normal-appearing urothelium (N = 234 were evaluated separately. Results Bladder cancer was observed in 23 cases (39.0% who underwent a biopsy of suspicious-appearing urothelium. Among these 23 cases, 9 cases with visible tumor resection had carcinoma in situ (CIS only in the biopsies from suspicious-appearing urothelium. Urinary cytology was negative in 3 of the 9 cases. Bladder cancer was observed in 26 cases (11.1% who underwent a biopsy of normal-appearing urothelium. Of them, 5 cases with visible tumors had CIS only in the multiple biopsies from normal-appearing urothelium. Urinary cytology was positive in all of the 5 cases. No upstaging or upgrading cases were found in these patients by the addition of these two types of biopsy. Furthermore, therapy was not altered in these patients. With or without bladder biopsy was not a significant factor for tumor recurrence in either the univariate or multivariate analysis. Conclusions Based on the results, it is concluded the multiple biopsies from normal-appearing urothelium are not necessary in patients with negative cytology results because of the low detection rate and lack of influence on therapeutic decisions. Meanwhile, biopsy of suspicious-appearing urothelium is needed in patients with negative cytology results in order to detect CIS due to staging properties. This result supports a recent EAU guideline.

  4. Terms and definitions of quality assurance/quality control

    International Nuclear Information System (INIS)

    Terms of quality assurance are defined and interpreted. Reference is made to the IAEA Code of Practice and to other important Codes and Standards like ANSI, ASME and KTA. The relevance of these terms to everyday's work and problems of a quality assurance engineer is explained. (orig.)

  5. Quality control in nuclear fuel fabrication

    International Nuclear Information System (INIS)

    The department of metallurgy, NRC Inchass is embarking on a programme of on a laboratory scale, fuel pins containing uranium dioxide pellets are going to be produced. The department is making use of the expertise and equipment at present available and is going to utilize the new fuel pin fabrication unit which would be shortly in operation. The fabrication and testing of uranium dioxide pellets then gradually adapt them and develop, a national know how in this field. This would also involve building up of indigenous experience through proper training of qualified personnel. That are applied to ensure quality of U o2 pellets, the techniques implemented, the equipment used and the specifications of the equipment presently available. The following parameters are subject to quality control tests: density. O/U ration, hydrogen content, microstructure, each property will be discussed, measurements related to U o2 powders, including flow ability, bulk density, O/U ratio, bet surface area and water content will be critically discussed. Relevant tests to ensure Q C of pellets are reviewed. These include surface integrity, density, dimensions, microstructure.4 fig., 1 tab

  6. Quality control of ATLAS muon chambers

    CERN Document Server

    Fabich, Adrian

    ATLAS is a general-purpose experiment for the future Large Hadron Collider (LHC) at CERN. Its Muon Spectrometer will require ∼ 5500m2 of precision tracking chambers to measure the muon tracks along a spectrometer arm of 5m to 15m length, embedded in a magnetic field of ∼ 0.5T. The precision tracking devices in the Muon System will be high pressure drift tubes (MDTs). Approximately 370,000 MDTs will be assembled into ∼ 1200 drift chambers. The performance of the MDT chambers is very much dependent on the mechanical quality of the chambers. The uniformity and stability of the performance can only be assured providing very high quality control during production. Gas tightness, high-voltage behaviour and dark currents are global parameters which are common to gas detectors. For all chambers, they will be tested immediately after the chamber assembly at every production site. Functional tests, for example radioactive source scans and cosmic-ray runs, will be performed in order to establish detailed performan...

  7. Quality control tests for conventional mammography

    International Nuclear Information System (INIS)

    Mammography is this the test that allows the radiologist to look at images of the inside of the breasts. Mammograms help detect breast cancer early successful treatment of breast cancer depends on that early diagnosis. Breast cancer is a very common condition. About one in every nine women develops breast cancer by the age of eighty. In addition to the clinical examination and self-examination, mammography plays important role in the detection of breast cancer before they become clinically visible tumors. The mammography is the most common test for early detection of breast cancer. Quality control techniques that done ensured importance of this programme to produce images with good diagnostic values and help radiologist to diagnose breast discase easily and avoid exposing patient to radiation hazards.(Author)

  8. Analytical quality control [An IAEA service

    International Nuclear Information System (INIS)

    In analytical chemistry the determination of small or trace amounts of elements or compounds in different types of materials is increasingly important. The results of these findings have a great influence on different fields of science, and on human life. Their reliability, precision and accuracy must, therefore, be checked by analytical quality control measures. The International Atomic Energy Agency (IAEA) set up an Analytical Quality Control Service (AQCS) in 1962 to assist laboratories in Member States in the assessment of their reliability in radionuclide analysis, and in other branches of applied analysis in which radionuclides may be used as analytical implements. For practical reasons, most analytical laboratories are not in a position to check accuracy internally, as frequently resources are available for only one method; standardized sample material, particularly in the case of trace analysis, is not available and can be prepared by the institutes themselves only in exceptional cases; intercomparisons are organized rather seldom and many important types of analysis are so far not covered. AQCS assistance is provided by the shipment to laboratories of standard reference materials containing known quantities of different trace elements or radionuclides, as well as by the organization of analytical intercomparisons in which the participating laboratories are provided with aliquots of homogenized material of unknown composition for analysis. In the latter case the laboratories report their data to the Agency's laboratory, which calculates averages and distributions of results and advises each laboratory of its performance relative to all the others. Throughout the years several dozens of intercomparisons have been organized and many thousands of samples provided. The service offered, as a consequence, has grown enormously. The programme for 1973 and 1974, which is currently being distributed to Member States, will contain 31 different types of materials

  9. The growing need for analytical quality control

    International Nuclear Information System (INIS)

    Technological development in a country is directly dependent upon its analytical chemistry or measurement capability, because it is impossible to achieve any level of technological sophistication without the ability to measure. Measurement capability is needed to determine both technological competence and technological consequence. But measurement itself is insufficient. There must be a standard or a reference for comparison. In the complicated world of chemistry the need for reference materials grows with successful technological development. The International Atomic Energy Agency has been distributing calibrated radioisotope solutions, standard reference materials and intercomparison materials since the early 1960's. The purpose of this activity has been to help laboratories in its Member States to assess and, if necessary, to improve the reliability of their analytical work. The value and continued need of this service has been demonstrated by the results of many intercomparisons which proved that without continuing analytical quality control activities, adequate reliability of analytical data could not be taken for granted. Analytical chemistry, lacking the glamour of other aspects of the physical sciences, has not attracted the attention it deserves, but in terms of practical importance, it warrants high priority in any developing technological scheme, because without it there is little chance to evaluate technological success or failure or opportunity to identify the reasons for success or failure. The scope and the size of the future programme of the IAEA in this field has been delineated by recommendations made by several Panels of Experts; all have agreed on the importance of this programme and made detailed recommendations in their areas of expertise. The Agency's resources are limited and it cannot on its own undertake the preparation and distribution of all the materials needed. It can, however, offer a focal point to bring together different

  10. Managerial Ability and Internal Control Quality: Evidence from China

    OpenAIRE

    2015-01-01

    Internal control quality of the firms can be determined by the firms¡¯ specific features, auditing quality and corporate governance. This research tries to make sure another factor-managerial ability is positively associated with internal control quality. With the evidences based on the A share in China¡¯s capital markets from 2009 to 2012, this research testifies that this relationship is statistically significant. Disclosing the internal control quality for all listed firms in China are man...

  11. Indoor air quality: sources and control

    International Nuclear Information System (INIS)

    The nature of the indoor air quality problem is described; methods of control or reduction of indoor radon and radon progeny concentrations have been reviewed. These techniques may be categorized as radon source reduction, radon removal, and radon progeny removal. There are a number of potential sources of radon in US housing, including soil, potable water, and building materials. In most cases, it appears that flow of radon-bearing soil gas into houses, driven by a slight negative pressure differential across the building shell, is a major source of indoor radon; this pressure-driven flow appears to be the most likely source of radon that can account for the elevated radon concentrations observed in some houses. There are a number of radon source control techniques; their effectiveness will depend upon characteristics of the house substructure and the details of the specific application. While the results of such remedial measures have varied and the data base from which to generalize is small, five-to-ten-fold reductions in radon concentration have been reported. 31 references, 4 figures

  12. Quality control of antibodies for assay development.

    Science.gov (United States)

    Schumacher, Sarah; Seitz, Harald

    2016-09-25

    Antibodies are used as powerful tools in basic research, for example, in biomarker identification, and in various forms for diagnostics, for example, identification of allergies or autoimmune diseases. Due to their robustness and ease of handling, immunoassays are favourite methods for investigation of various biological or medical questions. Nevertheless in many cases, additional analyses such as mass spectrometry are used to validate or confirm the results of immunoassays. To minimize the workload and to increase confidence in immunoassays, there are urgent needs for antibodies which are both highly specific and well validated. Unfortunately many commercially available antibodies are neither well characterized nor fully tested for cross-reactivities. Adequate quality control and validation of an antibody is time-consuming and can be frustrating. Such validation needs to be performed for every assay/application. However, where an antibody validation is successful, a highly specific and stable reagent will be on hand. This article describes the validation processes of antibodies, including some often neglected factors, as well as unspecific binding to other sample compounds in a multiparameter diagnostic assay. The validation consists of different immunological methods, with important assay controls, and is performed in relation to the development of a diagnostic test. PMID:26873787

  13. Requirements for quality control of analytical data

    International Nuclear Information System (INIS)

    The National Contingency Plan (NCP) of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) provides procedures for the identification, evaluation, and remediation of past hazardous waste disposal sites. The Hazardous Materials Response section of the NCP consists of several phases: Preliminary Assessment, Site Inspection, Remedial Investigation, Feasibility Study, Remedial Design, and Remedial Action. During any of these phases, analysis of soil, water, and waste samples may be performed. The Hazardous Waste Remedial Actions Program (HAZWRAP) is involved in performing field investigations and sample analyses pursuant to the NCP for the US Department of Energy and other federal agencies. The purpose of this document is to specify the requirements of Martin Marietta Energy Systems, Inc., for the control of accuracy, precision, and completeness of samples and data from the point of collection through analysis. Requirements include data reduction and reporting of resulting environmentally related data. Because every instance and concern may not be addressed in this document, HAZWRAP subcontractors are encouraged to discuss any questions with the Analytical Quality Control Specialist (AQCS) and the HAZWRAP Project Manager. This revision supercedes all other versions of this document

  14. 21 CFR 111.117 - What quality control operations are required for equipment, instruments, and controls?

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What quality control operations are required for equipment, instruments, and controls? 111.117 Section 111.117 Food and Drugs FOOD AND DRUG ADMINISTRATION... and Process Control System: Requirements for Quality Control § 111.117 What quality control...

  15. Minimal requirements for quality controls in radiotherapy with external beams

    International Nuclear Information System (INIS)

    Physical dosimetric guidelines have been developed by the Italian National Institute of Health study group on quality assurance in radiotherapy to define protocols for quality controls in external beam radiotherapy. While the document does not determine strict rules or firm recommendations, it suggests minimal requirements for quality controls necessary to guarantee an adequate degree of accuracy in external beam radiotherapy

  16. [Percutaneous biopsy of the liver].

    Science.gov (United States)

    Skladaný, L; Jarcuska, P; Oltman, M; Hrusovský, S

    2003-08-01

    Percutaneous liver biopsy represents the most specific examination of the nature and severity of liver diseases. P. Ehrlich was the first physician in history having done the intervention in 1880. The new history begins with the Menghini's publication on s.c. one-second biopsy in 1957. The present paper deals exclusively with diffuse diseases of the liver including the most frequent ones--virus hepatitis, alcohol and non-alcohol steatohepatitis. The contraindications include mainly coagulation disorders and non-cooperative patients. The percutaneous biopsy is mostly executed after ultrasonographic examination or under the control of various image-forming techniques and by means of various types of needles; the authors analyze advantages and disadvantages of individual techniques. If the contraindications are respected, the percutaneous biopsy is a safe method of examination, which may be done on out-patient basis. A large series of complications exists, but their frequency is generally low. Morbidity is referred in 0.2% of patients, the most frequent complications being pain and hypotension from vaso-vagal reactions, extensive intraperitoneal bleeding and hemobilia. Mortality is extremely low, the mean in large studies being 0.001%. PMID:14518095

  17. Improved transvenous liver biopsy needle

    DEFF Research Database (Denmark)

    Henriksen, Jens Henrik Sahl; Matzen, P; Christoffersen, P;

    1979-01-01

    A modified type of the standard transvenous cholangiography biopsy needle is described. The modified tranvenous liver biopsy needle caused only minimal artefactual changes of the liver biopsy specimens. The new type of biopsy needle is a modified Menghini needle. The conventional Menghini needle...... should be avoided for transvenous catheter biopsies because of risk of leaving catheter fragments in the liver....

  18. An Austrian framework for PET quality control

    International Nuclear Information System (INIS)

    Full text: The European patient protection directive (97/43 EURATOM) requires regular routine quality control (QC) of PET imaging devices. Since no standards were available covering this area and in order to comply with the directive a joint working party of the Austrian societies of nuclear medicine and of medical physics have developed a set of procedures suitable for both dedicated PET scanners and gamma cameras operating in coincidence mode (GCPET). The routine procedures proposed include both manufacturer recommended procedures and tests for specific parameters and calibration procedures. Wherever possible, procedures adapted or derived from NEMA standards publication NU 2-2001 were used to permit direct comparison with specified parameters of image quality. For dedicated PET scanners the most important procedures are the checking of detector sensitivities and the attenuation calibration scan. With full ring scanners the attenuation calibration scan is a blank scan, with partial ring devices a special attenuation calibration phantom has to be used. Test protocols are specific to manufacturer and scanner type. They are usually performed automatically overnight. In addition, some instruments require special calibrations, e.g. gain adjustments or coincidence timing calibration. GCPET procedures include the frequent assessment in coincidence mode of detector uniformity, energy resolution and system sensitivity. Common to both dedicated PET and GCPET are the regular quarterly assessment of tomographic spatial resolution and the calibration of the system for quantitative measurements. As a total performance test for both systems assessment of image quality following NU 2-2001 was included, to be carried out after major system changes or repairs. The suite of QC procedures was tested on several dedicated PET and GCPET systems including all major manufacturers' systems. Due to missing hardware or software not all tests could be performed on all systems. Some of the

  19. Quality control for overcoring stress measurement data

    International Nuclear Information System (INIS)

    The in situ state of stress is one of the key rock mechanical factors considering the safety and stability of underground excavations for civil and mining engineering purposes in greater depth, but at the same time measuring and interpretation of stress comes more difficult. Normally the in situ stress interpretation is based on final strain readings and there have not been practical and objective tools to judge transient strain behaviour during overcoring. This study was set up by nuclear waste management companies Posiva Oy (Finland) and Svensk Kaernbraenslehantering AB (Sweden) to improve the quality of interpretation of overcoring stress measurement results. The primary product of the project is quality control capability of overcoring stress measurement data. For this purpose a computer program was developed which can simulate the transient strains and stresses during the overcoring in any in situ stress and coring load conditions. The solution is based on superpositioning of elastic stresses and the basic idea can be applied also for different overcoring probes with minor modifications and recalculation of stress tensors. The measured strains can be compared to calculated ones to check if the measured transient behaviour is accordant with interpreted in situ state of stress. If not, the in situ state of stress can be calculated based any transient or final strain values. The transient stresses can be compared to strength envelope of intact rock and thereby estimate core damage potential. Technically the developed OCS-code fulfilled all the objectives and the numerical error was found to be less than 5%. The analysed case studies showed clearly the advance of having objective method study the reliability of stress measurement data. On the other hand, the interpretation of in situ state of stress from on early strains is difficult because the solution is very sensitive for measured strains and coring advance. The report also includes a comprehensive list of

  20. Production and quality control of 166 Ho

    International Nuclear Information System (INIS)

    Full text: Radioisotope production is one of the most important sectors in the mid and long term program of nuclear technology development. Therapeutic radiopharmaceuticals allow nuclear physicians to treat disease by attacking only the affected cells. The advantage of nuclear therapeutic over other therapies is that nuclear therapy can eliminate cancerous cells almost without harming healthy cells. Nuclear therapy would greatly improve quality of live by lowering the overall cost of the hospital, and reducing the time a patient stays in the hospital, and reducing the pain and suffering experienced by the patient. Several new radionuclides and carriers have recently been studied for treatment of various joint disorders. Ho-166 is a radionuclide with excellent physical properties for therapeutic application. Holmium-166 is produced by neutron capture on 100% abundant, stable holmium-165 with thermal neutron and resonance neutron cross section of 61.2 barns, respectively. It decays with 26.83 h half-life by emission of 1.855 MeV(51%) and 1.776 MeV (48%). Ho-166 also emits 80.5 keV gamma-ray in 6.2% abundance and, thus, is imageable by conventional techniques. Holmium-166 is utilized in radiotherapeutic applications such as radioimunospecific pharmaceuticals, bone marrow ablation, and radiation synovectomy. The radionuclide 166Ho is successfully produced by 165Ho (n,γ)166Ho reaction in the Nuclear Research Reactor (5 MW) at the neutron flux density 5*1013 n.cm-2.s-1. This study was focused to the preparation and quality control (especially of the radiochemical and radionuclide control) of the 166Ho. References: 1. Han .H .S, et al.: Current status and future plan for the production of radioisotopes using HANARO Research Reactor: journal of radioanalytical and Nuclear Chemistry, vol. 257, No.1 (2003) 47-51.; 2. Kyug Bae Park, Production Ho-166, IAEA-TECDOC-1340, IAEA: 71-74, 2003.; 3. Heuft-Dorenbusch L., et al.: Yttrium radiosynovectomy in the treatment of knee

  1. Biopsy pathology in uveitis

    Directory of Open Access Journals (Sweden)

    Jyotirmay Biswas

    2011-01-01

    Full Text Available Uveitis is fraught with speculations and suppositions with regard to its etiology, progress and prognosis. In several clinical scenarios what may be perceived as due to a systemic infection may actually not be so and the underlying etiology may be an autoimmune process. Investigations in uveitis are sometimes the key in identification and management. Invasive techniques could be of immense value in narrowing down the etiology and help in identifying the cause. This article updates one on the invasive techniques used in biopsy such as anterior chamber paracentesis, vitreous tap and diagnostic vitrectomy, iris and ciliary body biopsy, choroidal and retinochoroidal biopsy and fine needle aspiration biopsy (FNAB. In populations where certain infections are endemic, the clinical scenario does not always respect a known presentation and the use of biopsy is resorted to as a sure way of confirming the etiology. Biopsies have a role in diagnosis of several inflammatory and infectious conditions in the eye and are pivotal in diagnosis in several dilemmas such as intraocular tumors and in inflammations. Appropriate and timely use of biopsy in uveitis could enhance the diagnosis and provide insight into the etiology, thus enabling precise management.

  2. Freezing of testicular tissue as a minced suspension preserves sperm quality better than whole-biopsy freezing when glycerol is used as cryoprotectant.

    Science.gov (United States)

    Crabbé, E; Verheyen, G; Tournaye, H; Van Steirteghem, A

    1999-02-01

    Frozen-thawed testicular spermatozoa have been used successfully for ICSI, especially in cases of obstructive azoospermia with normal spermatogenesis. Fewer attempts, however, have been made to check whether these rather immature spermatozoa, in a different environment with several other cell types present, have cryobiological requirements other than those of ejaculated spermatozoa. This is the reason why the freezing protocols and cryoprotectants (glycerol) used for freezing testicular tissue are based on experience with semen freezing. This study aimed to assess whether cryosurvival and/or motility was influenced by freezing of testicular tissue either as an intact biopsy or as a shredded tissue suspension, when glycerol was used as cryoprotectant. Freezing of testicular tissue as a suspension preserved motility (type B + C) significantly better than freezing of whole biopsies (9.2% vs. 4.0%). Similar observations have been made for vitality (39.3% vs. 25.4%). Centrifugation on 50% Percoll in order to remove the cryoprotectant resulted in a huge loss of spermatozoa (or late spermatids) and should therefore be especially avoided in cases of testicular failure. On the basis of these observations, mincing of the testicular biopsies before freezing may be advocated. Testicular spermatozoa seem to be better preserved when frozen in suspension, at least when slowly permeating glycerol is used as a cryoprotectant. PMID:10068943

  3. 'Microerosions' in rectal biopsies in Crohn's disease

    DEFF Research Database (Denmark)

    Poulsen, Steen Seier

    1984-01-01

    Small (less than 1 mm), superficial erosions ('microerosions') have been observed stereo-microscopically in surface-stained rectal biopsies in Crohn's disease (CD). Biopsy specimens from 97 patients with CD, 225 with ulcerative colitis (UC), and a control material of 161 patients were investigated...... exclusively. Granulomas were identified in 62% of the biopsies with microerosions and by examination of two consecutive biopsies from each of these patients, in 85% indicating a positive correlation. In patients with microerosions and a primary diagnosis of UC, granulomas were found in 38% and by examination...... of two biopsies in 54%. Patients with granulomas and a few other patients were reclassified as CD, but there still remained some patients with microerosions, who most probably had UC. In conclusion, microerosions are observed mainly in CD with colonic involvement. There is a high incidence of...

  4. Concrete and steel construction quality control and assurance

    CERN Document Server

    El-Reedy, Mohamed A

    2014-01-01

    Starting with the receipt of materials and continuing all the way through to the final completion of the construction phase, Concrete and Steel Construction: Quality Control and Assurance examines all the quality control and assurance methods involving reinforced concrete and steel structures. This book explores the proper ways to achieve high-quality construction projects, and also provides a strong theoretical and practical background. It introduces information on quality techniques and quality management, and covers the principles of quality control. The book presents all of the quality control and assurance protocols and non-destructive test methods necessary for concrete and steel construction projects, including steel materials, welding and mixing, and testing. It covers welding terminology and procedures, and discusses welding standards and procedures during the fabrication process, as well as the welding codes. It also considers the total quality management system based on ISO 9001, and utilizes numer...

  5. Crop quality control system : a tool to control the visual quality of pot plants

    OpenAIRE

    Dijkshoorn-Dekker, M.W.C.

    2002-01-01

    Key words: quality, growth, model, leaf unfolding rate, internode, plant height, plant width, leaf area, temperature, plant spacing, season, light, development, image processing, grading, neural network, pot plant, Ficus benjamina 'Exotica'.The market is increasingly dictating the specifications for products. A well-defined marketable product must be delivered at a defined moment in time. A system was developed for growers to control development and growth of pot plants to achieve a defined q...

  6. Quality assurance and quality control of nuclear analytical techniques

    International Nuclear Information System (INIS)

    Test and analytical laboratories in East and Central European countries need to prove the reliability and credibility of their economic, environmental, medical and legal decisions and their capacity of issuing reliable, verifiable reports. These demands imposed by the European Union aimed at avoiding a possible barrier to trade for the developing countries. In June 1999, in order to help Member States to develop according to EU objectives and the overall situation of the European market, IAEA launched a new co-operation programme designed to help the nuclear analytical laboratories in nuclear institutions and universities of Member States by training in the use of some Nuclear Analytical Techniques (NAT) that include: alpha, beta and gamma-ray spectrometry, radiochemical and neutron activation analysis, total reflection X-ray fluorescence. The Regional IAEA Project, named 'Quality Assurance/Quality Control of Nuclear Analytical Techniques' (NAT) aims at implementing the QA principles via a system of defined consecutive steps leading to a level on which the QA system is self-sustainable for formal accreditation or certification and satisfies the EU technical performance criteria; the requirements are in accordance with the new ISO/IEC 17025 Standard/Dec.1999 'General requirements for the competence of testing and calibration laboratories' - First edition. The Horia Hulubei National Institute for Nuclear Physics and Engineering, IFIN-HH, was admitted for participation in the IAEA Project in June 1999 account taken of its experience in the QA and metrology fields and its performance in the fields of beta and gamma-ray spectrometry, and radiochemical and neutron activation analysis, employed in both basic research and applications for external clients. Two working groups of specialists with the QA and Standardization and Metrology Departments and six analytical groups with the departments of Nuclear Applied Physics, Life Physics and Ionising Radiation Metrology are

  7. Technicalities of endoscopic biopsy.

    Science.gov (United States)

    Tytgat, G N; Ignacio, J G

    1995-11-01

    Despite the wealth of biopsy forceps currently available, it is obvious that there are sufficient drawbacks and shortcomings to reconsider the overall design of the endoscopic biopsy depth, the short lifespan of reusable forceps, damage to the working channel, excessive time consumption, cleaning and disinfection difficulties, etc. Improvements should be possible that approach the same degree of sophistication as is currently available in endoscopic equipment. Fully-automated, repetitive, quickly targeted biopsy sampling should be possible, but it will require the utmost technical ingenuity and expertise to achieve. PMID:8903983

  8. No need for biopsies

    DEFF Research Database (Denmark)

    Gjødsbøl, Kristine; Skindersoe, Mette E; Christensen, Jens Jørgen;

    2011-01-01

    The aim of the study was to compare three sampling techniques used in routine diagnostics to identify the microbiota in chronic venous leg ulcers. A total of 46 patients with persisting venous leg ulcers were included in the study. At inclusion, swab, biopsy and filter paper pad samples were...... collected. After 4 weeks, additional biopsy and filter paper pad samples were collected. Bacteria were isolated and identified at species level by standard methods. The most common bacterial species detected was Staphylococcus aureus found in 89% of the ulcers. No methicillin-resistant S. aureus isolates...... species present in chronic wounds, thus avoiding complications during and after biopsy sampling....

  9. Quality assurance standards for purchasing and inventory control.

    Science.gov (United States)

    Soares, D P

    1985-03-01

    A process is described for quality assurance in pharmaceutical purchasing and inventory control. A quality assurance program should ensure that quality drugs are purchased at the lowest price, drug products are available when needed, the system is managed efficiently, internal controls are provided, drug products are stored under appropriate conditions, and laws, regulations, accreditation standards, and procedures are followed. To meet these objectives, product quality, vendor performance, the department's system of internal controls, purchasing data, and storage conditions should be monitored. A checklist for evaluating purchasing and inventory practices and a sample audit form listing quality assurance criteria, standards, procedures, and recommended actions are provided. A quality assurance program for pharmaceutical purchasing and inventory control should define institution-specific criteria and standards and use these standards for continual evaluation of all aspects of the purchasing and inventory control system. Documentation of quality assurance activities should be provided for use by the purchasing department, hospital administration, and regulatory bodies. PMID:3985026

  10. Descriptive study of the quality control in mammography

    International Nuclear Information System (INIS)

    The goal of mammography is to provide contrast between a lesion that is possible residing within the breast and normal surrounding tissue. Quality control is essential for maintaining the contrast imaging performance of a mammography system and incorporate tests that are relevant in that they are predictive of future degradation of contrast imaging performance. These tests will also be done at frequency that is high enough to intercept most drifts in quality imaging or performance before they become diagnostically significant. The quality control study has as objective to describe the results of the assessment of quality imaging elements (film optical density, contrast (density difference), uniformity, resolution and noise) of 62 mammography departments without quality control program and comparison these results with a mammography reference department with a quality control program. When comparing the results they allow seeing the clinical utility of to have a quality control program to reduce the errors of mammography interpretation. (Author)

  11. Toward standardising gamma camera quality control procedures

    Science.gov (United States)

    Alkhorayef, M. A.; Alnaaimi, M. A.; Alduaij, M. A.; Mohamed, M. O.; Ibahim, S. Y.; Alkandari, F. A.; Bradley, D. A.

    2015-11-01

    Attaining high standards of efficiency and reliability in the practice of nuclear medicine requires appropriate quality control (QC) programs. For instance, the regular evaluation and comparison of extrinsic and intrinsic flood-field uniformity enables the quick correction of many gamma camera problems. Whereas QC tests for uniformity are usually performed by exposing the gamma camera crystal to a uniform flux of gamma radiation from a source of known activity, such protocols can vary significantly. Thus, there is a need for optimization and standardization, in part to allow direct comparison between gamma cameras from different vendors. In the present study, intrinsic uniformity was examined as a function of source distance, source activity, source volume and number of counts. The extrinsic uniformity and spatial resolution were also examined. Proper standard QC procedures need to be implemented because of the continual development of nuclear medicine imaging technology and the rapid expansion and increasing complexity of hybrid imaging system data. The present work seeks to promote a set of standard testing procedures to contribute to the delivery of safe and effective nuclear medicine services.

  12. QUALITY CONTROL OF SOME TRADITIONAL MEAT PRODUCTS

    Directory of Open Access Journals (Sweden)

    S. DOBRINAS

    2014-03-01

    Full Text Available In this paper, we present the characterization of six traditional meat products: smoked file, smoked bacon, pork sausages, sausage prepared from swine’s entrails, pork pastrami, sheep sausages. Organoleptic tests (the aspect and shape, the aspect of freshly cut in the section, smell, taste and consistency, physico-chemical and microbiological determinations (NTG, Salmonella, Listeria monocytogenes and Escherichia coli were performed. These analyzes are a part of quality control that must be done in order to obtain a certificate from the Ministry of Agriculture for a traditional product. After identification of H2S and starch and according to fat oxidation degree it was concluded that analyzed samples didn’t contain counterfeiters and all parameters analyzed are within the maximum limits allowed by law. Considering all the procedures for manufacturing, characteristics of raw and auxiliary materials, organoleptic properties of final products analyzed in this study, it can be concluded that analyzed meat specialties meet the requirements of Ministry Order no. 690/28.09.2004 for the traditional products certification.

  13. SALE, Quality Control of Analytical Chemical Measurements

    International Nuclear Information System (INIS)

    1 - Description of problem or function: The Safeguards Analytical Laboratory Evaluation (SALE) program is a statistical analysis program written to analyze the data received from laboratories participating in the SALE quality control and evaluation program. The system is aimed at identifying and reducing analytical chemical measurement errors. Samples of well-characterized materials are distributed to laboratory participants at periodic intervals for determination of uranium or plutonium concentration and isotopic distributions. The results of these determinations are statistically evaluated and participants are informed of the accuracy and precision of their results. 2 - Method of solution: Various statistical techniques produce the SALE output. Assuming an unbalanced nested design, an analysis of variance is performed, resulting in a test of significance for time and analyst effects. A trend test is performed. Both within- laboratory and between-laboratory standard deviations are calculated. 3 - Restrictions on the complexity of the problem: Up to 1500 pieces of data for each nuclear material sampled by a maximum of 75 laboratories may be analyzed

  14. Quality control and reliability of reported doses

    International Nuclear Information System (INIS)

    Results of performance tests verifying the dosimetric properties of dosimetric systems are published in various reports (e.g. IAEA and EURADOS). However, there is hardly any information in the open literature relating to the uncertainty in a dose measurement or in the annual dose, which is increased by failure of the evaluation or data management system, damage of the dosemeter itself or by the loss of dosemeter. In this article, an attempt is made to estimate the importance of the above-mentioned conditions. This is achieved by sending questionnaires to about 200 approved dosimetric services in Europe. In total 88 questionnaires were returned and analysed. In the questionnaires, the frequency of occurrence of the various error conditions were investigated. Participants were also asked to evaluate the impact of the error condition from a dosimetric point of view and what countermeasures are taken. The article summarises all responses and compares different sources of errors according to their impact on the uncertainty of the resulting dose and gives a comprehensive overview on quality control actions and reliability on reported doses from European dosimetric services. (authors)

  15. The quality control theory of aging

    Directory of Open Access Journals (Sweden)

    Warren Ladiges

    2014-05-01

    Full Text Available The quality control (QC theory of aging is based on the concept that aging is the result of a reduction in QC of cellular systems designed to maintain lifelong homeostasis. Four QC systems associated with aging are 1 inadequate protein processing in a distressed endoplasmic reticulum (ER; 2 histone deacetylase (HDAC processing of genomic histones and gene silencing; 3 suppressed AMPK nutrient sensing with inefficient energy utilization and excessive fat accumulation; and 4 beta-adrenergic receptor (BAR signaling and environmental and emotional stress. Reprogramming these systems to maintain efficiency and prevent aging would be a rational strategy for increased lifespan and improved health. The QC theory can be tested with a pharmacological approach using three well-known and safe, FDA-approved drugs: 1 phenyl butyric acid, a chemical chaperone that enhances ER function and is also an HDAC inhibitor, 2 metformin, which activates AMPK and is used to treat type 2 diabetes, and 3 propranolol, a beta blocker which inhibits BAR signaling and is used to treat hypertension and anxiety. A critical aspect of the QC theory, then, is that aging is associated with multiple cellular systems that can be targeted with drug combinations more effectively than with single drugs. But more importantly, these drug combinations will effectively prevent, delay, or reverse chronic diseases of aging that impose such a tremendous health burden on our society.

  16. IAEA quality control exercises on bioindicators

    International Nuclear Information System (INIS)

    Biomonitoring air pollution using plants became an official part of the IAEA projects in 1997. In 1998 the section of Nutritional and Health Related Environmental Studies (NAHRES) organized a quality control exercise on two bioindicators (NAT-5 exercise), comprising two lichen samples. The first lichen was collected at an industrial polluted area in Austria, and the second was reference material IAEA-336, obtained from an unpolluted region in Portugal. 15 laboratories from 15 Member States participated in the NAT-5 exercise, providing 17 sets of results. The following analytical methods were used to obtain values: neutron activation analysis (NAA), inductive coupled plasma atomic emission spectrometry (ICP-AES), inductively coupled plasma mass spectrometry (ICP-MS), atomic absorption spectrometry (AAS), and particle induced X ray emission analysis (PIXE). 308 laboratory mean values for 47 elements were reported for the IAEA-336 lichen sample. More than 4 independent laboratory mean values were obtained for 26 elements and these were statistically evaluated. Only about 5% of the results were detected as outliers by the statistical tools. After statistical evaluation, the values were subjected to an assessment according to the recommended procedures for proficiency testing by interlaboratory comparisons (Draft ISO 13528). Reference values for 18 elements were available from the reference sheet of the material IAEA-336. The results presented illustrate the performance of the laboratories and show some discrepancy between non-destructive and destructive analytical techniques with elements of environmental interest. (author)

  17. MITOCHONDRIA QUALITY CONTROL AND MUSCLE MASS MAINTENANCE

    Directory of Open Access Journals (Sweden)

    Vanina eRomanello

    2016-01-01

    Full Text Available Loss of muscle mass and force occurs in many diseases such as disuse/inactivity, diabetes, cancer, renal and cardiac failure and in aging-sarcopenia. In these catabolic conditions the mitochondrial content, morphology and function are greatly affected. The changes of mitochondrial network influence the production of reactive oxygen species (ROS that play an important role in muscle function. Moreover, dysfunctional mitochondria trigger catabolic signaling pathways which feed-forward to the nucleus to promote the activation of muscle atrophy. Exercise, on the other hand, improves mitochondrial function by activating mitochondrial biogenesis and mitophagy, possibly playing an important part in the beneficial effects of physical activity in several diseases. Optimised mitochondrial function is strictly maintained by the coordinated activation of different mitochondrial quality control pathways. In this review we outline the current knowledge linking mitochondria-dependent signaling pathways to muscle homeostasis in aging and disease and the resulting implications for the development of novel therapeutic approaches to prevent muscle loss.

  18. Retroperitoneoscopic renal biopsy in children

    Directory of Open Access Journals (Sweden)

    Carlos M. Jesus

    2007-08-01

    Full Text Available OBJECTIVE: We present our experience in a series of 17 consecutive pediatric patients submitted to retroperitoneal laparoscopic renal biopsy. MATERIALS AND METHODS: Retroperitoneal laparoscopic renal biopsy (LRB was performed in 5 boys and 12 girls. Mean age was 8.1 years and age range from 2 to 12. Two or three trocars were used to expose the inferior pole of the kidney, remove enough cortical parenchymal specimen and fulgurate the biopsy site. Assessment included surgical time, estimated blood loss, hospitalization period, analgesia requirements, complications and number of glomeruli present in the specimen. RESULTS: LRB was successfully performed in all 15 patients (88%. In two cases, LRB was not possible to be performed. One patient was converted to a transperitoneal laparoscopy due to tear in the peritoneum. The other patient had had previous abdominal surgery and, during retroperitoneal balloon dilation, the peritoneum was opened and the open biopsy was performed. A third patient had postoperatively a perirenal hematoma, which was solved spontaneously. Complication rate was 17.6% (3/17 cases. Mean operative time was 65 minutes, while mean estimated blood loss was 52 mL, mean hospital stay was 2.2 days and mean analgesic requirement was 100 mg of tramadol. The mean number of glomeruli present in the specimen was 60. CONCLUSION: Retroperitoneal laparoscopic renal biopsy in children is a simple, safe. Bleeding is still the most common complication. However, direct vision usually allows a safe control of this drawback. In our institution, laparoscopic approach is the chosen procedure in pediatric patients older than one - year - old.

  19. Quality control with R an ISO standards approach

    CERN Document Server

    Cano, Emilio L; Prieto Corcoba, Mariano

    2015-01-01

    Presenting a practitioner's guide to capabilities and best practices of quality control systems using the R programming language, this volume emphasizes accessibility and ease-of-use through detailed explanations of R code as well as standard statistical methodologies. In the interest of reaching the widest possible audience of quality-control professionals and statisticians, examples throughout are structured to simplify complex equations and data structures, and to demonstrate their applications to quality control processes, such as ISO standards. The volume balances its treatment of key aspects of quality control, statistics, and programming in R, making the text accessible to beginners and expert quality control professionals alike. Several appendices serve as useful references for ISO standards and common tasks performed while applying quality control with R.

  20. Lung needle biopsy

    Science.gov (United States)

    ... if you have certain lung diseases such as emphysema. Usually, a collapsed lung after a biopsy does ... any type Bullae (enlarged alveoli that occur with emphysema) Cor pulmonale Cysts of the lung Pulmonary hypertension ...

  1. Pleural needle biopsy

    Science.gov (United States)

    ... et al, eds. Murray and Nadel's Textbook of Respiratory Medicine . 6th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 19. Ly A. Fine-needle aspiration biopsy technique and specimen ... Respiratory system. In: Watson N. Chapman and Nakielny's Guide ...

  2. 42 CFR 84.256 - Quality control requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Quality control requirements. 84.256 Section 84.256... § 84.256 Quality control requirements. (a) In addition to the construction and performance requirements specified in §§ 84.251, 84.252, 84.253, 84.254, and 84.255, the quality control requirements in...

  3. Quality-Driven Synthesis and Optimization of Embedded Control Systems

    OpenAIRE

    Samii, Soheil

    2011-01-01

    This thesis addresses several synthesis and optimization issues for embedded control systems. Examples of such systems are automotive and avionics systems in which physical processes are controlled by embedded computers through sensor and actuator interfaces. The execution of multiple control applications, spanning several computation and communication components, leads to a complex temporal behavior that affects control quality. The relationship between system timing and control quality is a...

  4. Auditor independence, audit committee quality and internal control weaknesses

    OpenAIRE

    Sorinel Domnișoru; Sorin-Sandu Vînătoru

    2008-01-01

    In this paper we investigate the relation between auditor independence, audit committee quality and the disclosure of internal control weaknesses. We begin with a sample of firms with internal control weaknesses and, based on industry, size, and performance, match these firms to a sample of control firms without internal control weaknesses. Our conditional logit analyses indicate that a relation exists between audit committee quality, auditor independence, and internal control weaknesses. Fir...

  5. Biopsy in Musculoskeletal Tumors

    Directory of Open Access Journals (Sweden)

    Mohammad Gharehdaghi

    2014-09-01

    Full Text Available Diagnosis of bone tumors is based on careful evaluation of clinical, imaging and a pathologic findings. So the biopsy of bone and soft tissue sarcomas is the final step in evaluation and a fundamental step in the diagnosis of the lesion. It should not be performed as a shortcut to diagnosis (1. The biopsy should be performed in order to confirm the diagnosis and differentiate among few diagnoses after careful staged studies. Real and artificial changes in imaging studies will be superimposed after performing biopsy, which may alter the interpretation if done after biopsy is taken (1. The correct management of a sarcoma depends on the accurate diagnosis. Inadequate, inapprppriate, or inaccurate non-representative biopsy leads to poorer outcome in terms of survivorship and limb salvage. An incorrect, unplanned incision and biopsy may unnecessarily contaminate uninvolved compartments which may convert a salvageable limb to amputation. Anatomic approach along with the proper biopsy techniques may lead to success or catastrophe. It is clear that in patients with inappropriate biopsy, the chance of the need to change the treatment to more radical than would originally be expected is significantly higher. Also it is more probable to need to  convert curative to palliative treatment and to require adjuvant radiotherapy in patients with inappropriate biopsies. Patients with sarcoma are best served by early referral to a specialized center where staged investigations and biopsy can be performed with minimal morbidity (3. Open biopsy is still considered the gold standard; however, recent studies suggest comparable results with percutaneous core needle biopsy. Our study on 103 consecutive CNB and open biopsy showed comparable results as well. Surgeons need to answer to two questions prior to performing a biopsy: 1-          Where is the best part of the lesion to be biopsied? 2-          What is the safest route without contaminating

  6. Quality assurance in food irradiation with emphasis on process control

    International Nuclear Information System (INIS)

    Process control is an essential component of quality assurance in food irradiation. This paper discusses the key elements of process control of gamma and electron beam irradiation of foods. They include irradiated product investigation and qualification, irradiator qualification (commissioning), dosimetry including calibration and dose-mapping, licensing documentation and inspection, and, details of routine process control. Radiation process control combined with incoming product quality control and outgoing (processed) product handling, etc., control constitute the essence of overall quality assurance in food irradiation. (author). 11 refs

  7. Corpus vitreum, retina og chorioidea biopsi

    DEFF Research Database (Denmark)

    Scherfig, Erik Christian Høegh

    2002-01-01

    oftalmology, biopsy, choroid, corpus vitreum, retina, malignant melanoma, biopsy technic, retinoblastoma......oftalmology, biopsy, choroid, corpus vitreum, retina, malignant melanoma, biopsy technic, retinoblastoma...

  8. Proteomics Quality Control: Quality Control Software for MaxQuant Results.

    Science.gov (United States)

    Bielow, Chris; Mastrobuoni, Guido; Kempa, Stefan

    2016-03-01

    Mass spectrometry-based proteomics coupled to liquid chromatography has matured into an automatized, high-throughput technology, producing data on the scale of multiple gigabytes per instrument per day. Consequently, an automated quality control (QC) and quality analysis (QA) capable of detecting measurement bias, verifying consistency, and avoiding propagation of error is paramount for instrument operators and scientists in charge of downstream analysis. We have developed an R-based QC pipeline called Proteomics Quality Control (PTXQC) for bottom-up LC-MS data generated by the MaxQuant1 software pipeline. PTXQC creates a QC report containing a comprehensive and powerful set of QC metrics, augmented with automated scoring functions. The automated scores are collated to create an overview heatmap at the beginning of the report, giving valuable guidance also to nonspecialists. Our software supports a wide range of experimental designs, including stable isotope labeling by amino acids in cell culture (SILAC), tandem mass tags (TMT), and label-free data. Furthermore, we introduce new metrics to score MaxQuant's Match-between-runs (MBR) functionality by which peptide identifications can be transferred across Raw files based on accurate retention time and m/z. Last but not least, PTXQC is easy to install and use and represents the first QC software capable of processing MaxQuant result tables. PTXQC is freely available at https://github.com/cbielow/PTXQC . PMID:26653327

  9. Evaluation of a Biopsy Gun for Guided Biopsy of Impalpable Liver Lesions Using Intraoperative Utrasound

    OpenAIRE

    Charnley, R. M.; Sheffield, J P; Hardcastle, J. D.

    1990-01-01

    A biopsy gun which can be operated by one hand has been evaluated at post-mortem to determine its accuracy in biopsying impalpable lesions within the liver under intraoperative ultrasound control. Of 20 impalpable metastases identified positive histology was obtained in 90% demonstrating that this technique is of value in identifying and localising metastases in the liver.

  10. Quality control by a mobile molecular workshop: quality versus quantity

    CERN Document Server

    Sharma, Ajeet K

    2010-01-01

    Ribosome is a molecular machine that moves on a mRNA track while, simultaneously, polymerizing a protein using the mRNA also as the corresponding template. We introduce quantitative measures of its performance which characterize, for example, the speed and fidelity of the template-dictated polymerization. We also define two different measures of efficiency and strength of mechano-chemical coupling of this molecular machine. We calculate all these quantities analytically. Some of these quantities show apparently counterintuitive trends of variation with the quality of kinetic proofreading. We interpret the origin of these trends. We suggest new experiments for testing some of the ideas presented here.

  11. Methods for Prostate Biopsy

    Directory of Open Access Journals (Sweden)

    M. Ghafoori

    2008-01-01

    Full Text Available Prostate cancer is currently the most prevalent form of cancer in men and the second leading cause of can-cer death in the United States, and the third most common cancer in men worldwide. Increasing mor-tality rates due to prostate carcinoma have been ob-served worldwide. This disease usually progresses im-perceptibly; thus, patients are unlikely to seek medi-cal help during the early stages. For these reasons, screening programs aimed at early detection have been developed. The prostate-specific antigen (PSA test is among the best screening tools available in medicine today and is recognized as the best marker for its early detection. Prostate cancers detected by DRE method alone are clinically localized only 50% to 60% of the time, whereas PSA-detected tumors are clinically localized 90% of the time and pathologi-cally confined to the prostate as determined at prostatectomy about two thirds of the time. Recently, the detection of localized prostate cancers has improved, owing to the development of various new biopsy methods. However, a standard biopsy method, including number of cores, has not yet been established at present. When screening results indi-cate the possibility of prostate cancer, a pathologic diagnosis may be pursued by ultrasound guided trans-rectal needle biopsy. Prostate biopsy is usually ad-vised if serum PSA is >4 ng/mL, and this procedure remains the gold standard for prostate cancer diagno-sis. Fine needle biopsy is less painful than core bi-opsy, but also less diagnostically accurate. Systematic biopsy protocols: In 1989, Hodge et al. coined the sextant biopsy method that is still the standard of reference in prostate cancer detection. The prostate is bilaterally divided into three regions (apex, midgland, and base, all of which are system-atically biopsied once. Although Hodge et al. first proposed sextant biopsy under transrectal ultrasound guidance, some recent reports have indicated that systematic sextant biopsy

  12. Food and Nutrition Services Quality Control Management Program.

    Science.gov (United States)

    Wimsatt-Fraim, Teresa S.

    A program was conducted to improve the quality of food service through the training of 44 food and nutrition service employees in a 200-bed hospital. A 12-week quality control program was implemented to address four key areas: food temperatures, food accuracy, food quality, and dietary personnel. Learning strategies, emphasizing critical thinking…

  13. Quality control and management of technegas generator

    International Nuclear Information System (INIS)

    Technegas generator is an important part of imaging devices of nuclear medicine department. Daily maintenance and management will be very helpful to ensure stability of instrument performance, reduce failure rate of instrument, ensure examination quality and reduce expenses. (authors)

  14. Teaching Quality Control with Chocolate Chip Cookies

    Science.gov (United States)

    Baker, Ardith

    2014-01-01

    Chocolate chip cookies are used to illustrate the importance and effectiveness of control charts in Statistical Process Control. By counting the number of chocolate chips, creating the spreadsheet, calculating the control limits and graphing the control charts, the student becomes actively engaged in the learning process. In addition, examining…

  15. Joint Determination of Optimal Inventory and Quality Control Policy

    OpenAIRE

    Michael H. Peters; Helmut Schneider; Kwei Tang

    1988-01-01

    Typically the operating policy for the inventory control system for a commodity is developed independent of the operating policy for the quality control system for that commodity and vice versa. In many circumstances, these systems are dependent on one another. A cost model that combines a fixed order quantity inventory control system with a Bayesian quality control system for a lot-by-lot attribute acceptance sampling plan is presented along with an algorithm to obtain the operating paramete...

  16. Control of Bank Consolidated Financial Statements Quality

    OpenAIRE

    Margarita S. Ambarchyan

    2013-01-01

    The author presents the multiple linear regression model of bank consolidated financial statements quality. The article considers six characteristics that can be used to estimate the level of bank consolidated financial statements quality. The multiple linear regression model was developed, using the results of point-based system of consolidated financial statements of thirty European bank and financial groups on the basis of the developed characteristics. The author offers to use the charact...

  17. Magnetotelluric quality control study and calibration survey

    International Nuclear Information System (INIS)

    We have performed a managetotelluric study in order to evaluate the data quality and reliability of magnetotelluric information obtained for Rockwell Hanford Operations by two sub-contractors. The motivation for performing this study resulted from: relatively poor and variable data quality and some major disagreements between the results obtained in these two surveys. Geotronics' task was to perform an analysis based on the material included in these survey reports and other available information

  18. Use of a newly developed piezoelectrically driven drilling machine for MR-guided bone biopsies

    International Nuclear Information System (INIS)

    Purpose: Development and clinical testing of an MR-compatible bone biopsy system, to enable the sample collection from osteosclerotic or subcortical lesions for histological investigation under MR control. Materials and Methods: A piezoelectrically driven drilling machine was constructed and tested in connection with an MR-compatible bone biopsy set in a vertical open MR scanner (0.5 T) on a phantom and 10 patients with ambiguous bone lesions. Images were obtained using T1-weighted spin-echo sequences and, in case of real-time imaging, a fast spoiled gradient-echo sequence. Results: The influence of the enabled motor (RF-interference) leads to a reduction of the signal to noise ratio of the images, but can be minimised by appropriate measures. The observed slight field distorsions do not affect the image quality during real time acquisition in a substantial manner. No complications occurred. The extracted biopsy material was sufficient and of good quality. Conclusions: In spite of slightly restricted image quality, the described drilling machine combined with the bone biopsy set is well suited for MR-guided bone biopsies, which require the application of a motor driven drill. Its application within an interventional MR scanner is safe and its handling simple and manageable. (orig.)

  19. Negative Biopsy after Referral for Biopsy-Proven Gastric Cancer

    OpenAIRE

    Tae, Chung Hyun; Lee, Jun Haeng; Min, Byung-Hoon; Kim, Kyoung-Mee; Rhee, Poong-Lyul; Kim, Jae J

    2016-01-01

    Background/Aims Repeat endoscopy with biopsy is often performed in patients with previously diagnosed gastric cancer to determine further treatment plans. However, biopsy results may differ from the original pathologic report. We reviewed patients who had a negative biopsy after referral for gastric cancer. Methods A total of 116 patients with negative biopsy results after referral for biopsy-proven gastric cancer were enrolled. Outside pathology slides were reviewed. Images of the first and ...

  20. Quality control protocols for radiodiagnosis agents and radiopharmaceuticals

    International Nuclear Information System (INIS)

    Based on the compilation of pharmacopoeia methods, literature, manuals and other information developed in our laboratory, protocols have been prepared to carry out quality controls for radiodiagnosis agents (RDA), better known as kits and RDA labelled with Tc99m. Quality control protocols cover physicochemical and biological controls. Physicochemical controls described for RDA include physical characteristics, particle size and number, pH, chemical identification, humidity, tin II; whereas biological controls include sterility, acute toxicity and bacterial endotoxin determination (LAL). Physicochemical controls described for radiopharmaceuticals labelled with Tc99m are pH and radiochemical purity; while biological distribution is described as a biological control

  1. Chemical and physical quality control of the HIPPURAN-131I

    International Nuclear Information System (INIS)

    Some physico-chemical methods for analytical control of Hippuran-131I are compared. The most convenient to applicate in hospitals and in more specialized quality control laboratories are recommended. The quality of Hippuran-131I produced by ISOTOP (USSR) is also evaluated. The product met the requirement of the International Pharmacopeia

  2. Importance of critical evaluation in quality control of scintillation cameras

    International Nuclear Information System (INIS)

    The evaluation of quality control results in nuclear medicine must be performed with a critical view over the conditions the tests are executed. This paper is a result of observations in the routine quality control where we set up didactic 'findings' to show the importance of evaluating critical situations while executing the procedures. (author)

  3. 75 FR 41874 - Quality Control for Rental Assistance Subsidy Determinations

    Science.gov (United States)

    2010-07-19

    ... URBAN DEVELOPMENT Quality Control for Rental Assistance Subsidy Determinations AGENCY: Office of the.... This notice also lists the following information: Title of Proposal: Quality Control for Rental... agency's estimate of the burden of the proposed collection of information; (3) Enhance the...

  4. Procedures for quality control of thermoluminescent dosimetry laboratory

    International Nuclear Information System (INIS)

    In order to assurance the results accuracy of a thermoluminescence dosimetry laboratory it is necessary a quality control program. For a laboratory in operation, without a structured program, the quality control should be started for documentation of its technical and administrative procedures. It is presented a proposal with the essential procedures to carry out this program. (author)

  5. Artificial Intelligence Approach to Support Statistical Quality Control Teaching

    Science.gov (United States)

    Reis, Marcelo Menezes; Paladini, Edson Pacheco; Khator, Suresh; Sommer, Willy Arno

    2006-01-01

    Statistical quality control--SQC (consisting of Statistical Process Control, Process Capability Studies, Acceptance Sampling and Design of Experiments) is a very important tool to obtain, maintain and improve the Quality level of goods and services produced by an organization. Despite its importance, and the fact that it is taught in technical and…

  6. Electronic quality control on dental x-rays equipment

    International Nuclear Information System (INIS)

    A brief description of dental x-ray equipment is done. The non-invasive quality control is treated as than the responsibilities from the dentists to the patient and the equipment. A propose for quality control for dental x-ray equipment, film and developer is include

  7. Status and future trends of Analytical Quality Control Services

    International Nuclear Information System (INIS)

    This report reviews the present Analytical Quality Control Services (AQCS) programme components in the light of the needs of IAEA Member States for analytical reference materials and intercomparisons, provides guidelines for the direction which the programme should take in the future and identifies the type of Analytical Quality Control Services most urgently required by the Member States

  8. Internal quality control in serological tests for syphilis.

    OpenAIRE

    Wasley, G. D.

    1985-01-01

    The importance of syphilis serological tests demands that laboratory reports are reliable. Internal quality control applied to the organisation of a syphilis serology service improves laboratory bench performance and reporting. Described here are internal quality control procedures of a department that serves a genitourinary medicine clinic and conducts 70 000 tests a year to investigate for syphilis.

  9. Transvenous liver biopsy via the femoral vein

    International Nuclear Information System (INIS)

    AIM: To study the safety, effectiveness and diagnostic value of transvenous forceps biopsy of the liver in 54 patients with coagulopathy, gross ascites or morbid obesity and suspected liver disease in whom percutaneous liver biopsy was contraindicated. MATERIAL AND METHODS: Forceps biopsy of the liver via the femoral vein was attempted in 54 adult patients with advanced liver disease of unknown aetiology who had coagulation disorders (41 cases), gross ascites (11 cases) or morbid obesity (two cases). In each patient two to six biopsies (average four) were taken using a radial jaw forceps inserted via the right or left femoral vein. RESULTS: The procedure was successful in 53 cases. Hepatic vein catheterization failed in one patient. Adequate liver tissue for diagnosis was obtained in 84% of cases. One patient developed delayed haemorrhage at 12 h from a capsular leak that was undetected during the biopsy procedure. This patient required blood transfusions and laparotomy to control bleeding. There were no deaths in the 53 patients studied. Transient minor chest and shoulder pain was encountered during sheath insertion into a hepatic vein in 23 patients. Three patients developed a femoral vein haematoma, which resolved with conservative treatment. CONCLUSION: Transvenous liver biopsy via the femoral vein is another safe, effective, simple alternative technique of biopsy when the percutaneous route is contraindicated

  10. Transvenous liver biopsy via the femoral vein

    Energy Technology Data Exchange (ETDEWEB)

    Khosa, F. E-mail: fkhosa@hotmail.com; McNulty, J.G.; Hickey, N.; O' Brien, P.; Tobin, A.; Noonan, N.; Ryan, B.; Keeling, P.W.N.; Kelleher, D.P.; McDonald, G.S.A

    2003-06-01

    AIM: To study the safety, effectiveness and diagnostic value of transvenous forceps biopsy of the liver in 54 patients with coagulopathy, gross ascites or morbid obesity and suspected liver disease in whom percutaneous liver biopsy was contraindicated. MATERIAL AND METHODS: Forceps biopsy of the liver via the femoral vein was attempted in 54 adult patients with advanced liver disease of unknown aetiology who had coagulation disorders (41 cases), gross ascites (11 cases) or morbid obesity (two cases). In each patient two to six biopsies (average four) were taken using a radial jaw forceps inserted via the right or left femoral vein. RESULTS: The procedure was successful in 53 cases. Hepatic vein catheterization failed in one patient. Adequate liver tissue for diagnosis was obtained in 84% of cases. One patient developed delayed haemorrhage at 12 h from a capsular leak that was undetected during the biopsy procedure. This patient required blood transfusions and laparotomy to control bleeding. There were no deaths in the 53 patients studied. Transient minor chest and shoulder pain was encountered during sheath insertion into a hepatic vein in 23 patients. Three patients developed a femoral vein haematoma, which resolved with conservative treatment. CONCLUSION: Transvenous liver biopsy via the femoral vein is another safe, effective, simple alternative technique of biopsy when the percutaneous route is contraindicated.

  11. French permanent survey on indoor air quality - Part 1.: Measurement protocols and quality control

    OpenAIRE

    Ramalho, Olivier; Derbez, Mickael; Gregoire, Anthony; Garrigue, Julien; Kirchner, Séverine

    2006-01-01

    This paper focuses on a synthesis of the measurement and analytical protocols from the 2003-2005 campaign of the French permanent survey on indoor air quality and presents the associated quality control system including data traceability, quality code and interlaboratory tests. Preliminary exploitation of measurement and analysis errors are presented

  12. How to set up and manage quality control and quality assurance

    NARCIS (Netherlands)

    Visschedijk, M.; Hendriks, R.; Nuyts, K.

    2005-01-01

    This document provides a general introduction to clarify the differences between quality control (QC) and quality assurance (QA). In addition it serves as a starting point for implementing a quality system approach within an organization. The paper offers practical guidance to the implementation of

  13. Computational optical biopsy

    Directory of Open Access Journals (Sweden)

    Jiang Ming

    2005-06-01

    Full Text Available Abstract Optical molecular imaging is based on fluorescence or bioluminescence, and hindered by photon scattering in the tissue, especially in patient studies. Here we propose a computational optical biopsy (COB approach to localize and quantify a light source deep inside a subject. In contrast to existing optical biopsy techniques, our scheme is to collect optical signals directly from a region of interest along one or multiple biopsy paths in a subject, and then compute features of an underlying light source distribution. In this paper, we formulate this inverse problem in the framework of diffusion approximation, demonstrate the solution uniqueness properties in two representative configurations, and obtain analytic solutions for reconstruction of both optical properties and source parameters.

  14. Importance of Local Control in Early-Stage Prostate Cancer: Outcomes of Patients With Positive Post-Radiation Therapy Biopsy Results Treated in RTOG 9408

    International Nuclear Information System (INIS)

    Purpose: The purpose of this study was to assess the association between positive post-radiation therapy (RT) biopsy results and subsequent clinical outcomes in males with localized prostate cancer. Methods and Materials: Radiation Therapy Oncology Group study 94-08 analyzed 1979 males with prostate cancer, stage T1b-T2b and prostate-specific antigen concentrations of ≤20 ng/dL, to investigate whether 4 months of total androgen suppression (TAS) added to RT improved survival compared to RT alone. Patients randomized to receive TAS received flutamide with luteinizing hormone releasing hormone (LHRH) agonist. According to protocol, patients without evidence of clinical recurrence or initiation of additional endocrine therapy underwent repeat prostate biopsy 2 years after RT completion. Statistical analysis was performed to evaluate the impact of positive post-RT biopsy results on clinical outcomes. Results: A total of 831 patients underwent post-RT biopsy, 398 were treated with RT alone and 433 with RT plus TAS. Patients with positive post-RT biopsy results had higher rates of biochemical failure (hazard ratio [HR] = 1.7; 95% confidence interval [CI] = 1.3-2.1) and distant metastasis (HR = 2.4; 95% CI = 1.3-4.4) and inferior disease-specific survival (HR = 3.8; 95% CI = 1.9-7.5). Positive biopsy results remained predictive of such outcomes after correction for potential confounders such as Gleason score, tumor stage, and TAS administration. Prior TAS therapy did not prevent elevated risk of adverse outcome in the setting of post-RT positive biopsy results. Patients with Gleason score ≥7 with a positive biopsy result additionally had inferior overall survival compared to those with a negative biopsy result (HR = 1.56; 95% CI = 1.04-2.35). Conclusions: Positive post-RT biopsy is associated with increased rates of distant metastases and inferior disease-specific survival in patients treated with definitive RT and was associated with inferior overall

  15. Importance of Local Control in Early-Stage Prostate Cancer: Outcomes of Patients With Positive Post-Radiation Therapy Biopsy Results Treated in RTOG 9408

    Energy Technology Data Exchange (ETDEWEB)

    Krauss, Daniel J., E-mail: dkrauss@beaumont.edu [Department of Radiation Oncology, Oakland University William Beaumont School of Medicine, Royal Oak, Michigan (United States); Hu, Chen [NRG Statistics and Data Management Center, Philadelphia, Pennsylvania (United States); Bahary, Jean-Paul [Centre Hospitalier de l' Université de Montréal-Notre Dame, Montreal, Quebec (Canada); Souhami, Luis [McGill University, Montreal, Quebec (Canada); Gore, Elizabeth M. [Medical College of Wisconsin, Milwaukee, Wisconsin (United States); Chafe, Susan Maria Jacinta [Cross Cancer Institute, Edmonton, Alberta (Canada); Leibenhaut, Mark H. [Sutter General Hospital, Sacramento, California (United States); Narayan, Samir [Michigan Cancer Research Consortium CCOP (United States); Torres-Roca, Javier [H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida (United States); Michalski, Jeff [Washington University, St. Louis, Missouri (United States); Zeitzer, Kenneth L. [Albert Einstein Medical Center, Bronx, New York, New York (United States); Donavanik, Viroon [Christiana Care Health Services Inc CCOP, Newark, Delaware (United States); Sandler, Howard [Cedars-Sinai Medical Center, Los Angeles, California (United States); McGowan, David G. [Cross Cancer Institute, Edmonton, Alberta (Canada); Jones, Christopher U. [Sutter General Hospital, Sacramento, California (United States); Shipley, William U. [Dana-Farber Cancer Institute, Boston, Massachusetts (United States)

    2015-07-15

    Purpose: The purpose of this study was to assess the association between positive post-radiation therapy (RT) biopsy results and subsequent clinical outcomes in males with localized prostate cancer. Methods and Materials: Radiation Therapy Oncology Group study 94-08 analyzed 1979 males with prostate cancer, stage T1b-T2b and prostate-specific antigen concentrations of ≤20 ng/dL, to investigate whether 4 months of total androgen suppression (TAS) added to RT improved survival compared to RT alone. Patients randomized to receive TAS received flutamide with luteinizing hormone releasing hormone (LHRH) agonist. According to protocol, patients without evidence of clinical recurrence or initiation of additional endocrine therapy underwent repeat prostate biopsy 2 years after RT completion. Statistical analysis was performed to evaluate the impact of positive post-RT biopsy results on clinical outcomes. Results: A total of 831 patients underwent post-RT biopsy, 398 were treated with RT alone and 433 with RT plus TAS. Patients with positive post-RT biopsy results had higher rates of biochemical failure (hazard ratio [HR] = 1.7; 95% confidence interval [CI] = 1.3-2.1) and distant metastasis (HR = 2.4; 95% CI = 1.3-4.4) and inferior disease-specific survival (HR = 3.8; 95% CI = 1.9-7.5). Positive biopsy results remained predictive of such outcomes after correction for potential confounders such as Gleason score, tumor stage, and TAS administration. Prior TAS therapy did not prevent elevated risk of adverse outcome in the setting of post-RT positive biopsy results. Patients with Gleason score ≥7 with a positive biopsy result additionally had inferior overall survival compared to those with a negative biopsy result (HR = 1.56; 95% CI = 1.04-2.35). Conclusions: Positive post-RT biopsy is associated with increased rates of distant metastases and inferior disease-specific survival in patients treated with definitive RT and was associated with inferior overall

  16. Proposed quality control protocol of a dual energy bone densitometer from Spanish protocol for quality control of radiology

    International Nuclear Information System (INIS)

    In this paper we propose additional testing to complete the tests by the Spanish Protocol for Quality Control of Diagnostic Radiology, taking into account the particular characteristics of these units, and including these tests in the estimation of patient dose dose assessment area. There is also the possibility to independently verify the quality control tests that are done automatically.

  17. PROCESS VARIABILITY REDUCTION THROUGH STATISTICAL PROCESS CONTROL FOR QUALITY IMPROVEMENT

    Directory of Open Access Journals (Sweden)

    B.P. Mahesh

    2010-09-01

    Full Text Available Quality has become one of the most important customer decision factors in the selection among the competing product and services. Consequently, understanding and improving quality is a key factor leading to business success, growth and an enhanced competitive position. Hence quality improvement program should be an integral part of the overall business strategy. According to TQM, the effective way to improve the Quality of the product or service is to improve the process used to build the product. Hence, TQM focuses on process, rather than results as the results are driven by the processes. Many techniques are available for quality improvement. Statistical Process Control (SPC is one such TQM technique which is widely accepted for analyzing quality problems and improving the performance of the production process. This article illustrates the step by step procedure adopted at a soap manufacturing company to improve the Quality by reducing process variability using Statistical Process Control.

  18. NIF Projects Controls and Information Systems Software Quality Assurance Plan

    International Nuclear Information System (INIS)

    Quality achievement for the National Ignition Facility (NIF) and the National Ignition Campaign (NIC) is the responsibility of the NIF Projects line organization as described in the NIF and Photon Science Directorate Quality Assurance Plan (NIF QA Plan). This Software Quality Assurance Plan (SQAP) is subordinate to the NIF QA Plan and establishes quality assurance (QA) activities for the software subsystems within Controls and Information Systems (CIS). This SQAP implements an activity level software quality assurance plan for NIF Projects as required by the LLNL Institutional Software Quality Assurance Program (ISQAP). Planned QA activities help achieve, assess, and maintain appropriate quality of software developed and/or acquired for control systems, shot data systems, laser performance modeling systems, business applications, industrial control and safety systems, and information technology systems. The objective of this SQAP is to ensure that appropriate controls are developed and implemented for management planning, work execution, and quality assessment of the CIS organization's software activities. The CIS line organization places special QA emphasis on rigorous configuration control, change management, testing, and issue tracking to help achieve its quality goals.

  19. NIF Projects Controls and Information Systems Software Quality Assurance Plan

    Energy Technology Data Exchange (ETDEWEB)

    Fishler, B

    2011-03-18

    Quality achievement for the National Ignition Facility (NIF) and the National Ignition Campaign (NIC) is the responsibility of the NIF Projects line organization as described in the NIF and Photon Science Directorate Quality Assurance Plan (NIF QA Plan). This Software Quality Assurance Plan (SQAP) is subordinate to the NIF QA Plan and establishes quality assurance (QA) activities for the software subsystems within Controls and Information Systems (CIS). This SQAP implements an activity level software quality assurance plan for NIF Projects as required by the LLNL Institutional Software Quality Assurance Program (ISQAP). Planned QA activities help achieve, assess, and maintain appropriate quality of software developed and/or acquired for control systems, shot data systems, laser performance modeling systems, business applications, industrial control and safety systems, and information technology systems. The objective of this SQAP is to ensure that appropriate controls are developed and implemented for management planning, work execution, and quality assessment of the CIS organization's software activities. The CIS line organization places special QA emphasis on rigorous configuration control, change management, testing, and issue tracking to help achieve its quality goals.

  20. Methodical Grounds of Managing the Product Quality Control

    Directory of Open Access Journals (Sweden)

    Shapoval Olena A.

    2014-01-01

    Full Text Available The article analyses the modern state of products quality control management. It justifies a necessity of organisation of the quality control system under conditions of uninterrupted flow line production. It reveals problems connected with a low level of the products quality control management. It forms a set of factors of internal and external environments, which should be taken into account in the process of selection of a type of managerial actions by the products quality control. It considers specific features of identification of the most important factors at an enterprise on the basis of use of the matrix of strategic SWOT analysis. It offers a procedure of identification of a general assessment of factors of influence. It analyses a mechanism of use of main conceptual models, which reflect the system nature of quality management in an organisation – quality pyramids and quality loops. It proves a necessity of application of a principally new scheme of relations between the customer and enterprise, which envisages that requirements of the quality management system focus not on control and screening of semi-finished products, but on creation of conditions that exclude rejects. It considers the role of ISO 9000 in the system of quality management, which recommend the customers to make a preliminary assessment of activity of the producing enterprise.

  1. Ultrasound- and MRI-Guided Prostate Biopsy

    Science.gov (United States)

    ... Index A-Z Ultrasound- and MRI-Guided Prostate Biopsy Ultrasound- and MRI-guided prostate biopsy uses imaging ... Biopsy? What is Ultrasound- and MRI-guided Prostate Biopsy? Ultrasound- and MRI-guided prostate biopsies are performed ...

  2. Justification and quality control in radiodiagnostics

    International Nuclear Information System (INIS)

    The role of the radiodiagnostician in justification of x-ray examination is discussed. Under the final responsibility of the radio-diagnostician the more common examinations are performed by laboratory assistants. A justification judgement before by the radio-diagnostician does not take place. In case of complicated examinations often previous consultation between radio-diagnostician and clinician is necessary. The fast development of new techniques like CT, echography and MRI has as result that the modern radio-diagnostician develops more and more into a imaging-specialist. In the consultation with the clinician he advises about the optimal diagnostics for a certain patient, taking optimally into account the risks of x-radiation. The justifying role of the radio-diagnostician depends further upon the relation with the requiring physician. In general the inter-collegial consultation is assumed to be sufficient within the hospitals, however the feedback to general practitioners seems to be improvable in some cases. With regard to quality assurance it is remarked that the quality of the examination may not be endangered by a too strong emphasis upon radiation reduction. Aspects like education level, protocol learning, dose limits, degressive tariffs, information-transfer, radiation passport, analysis between 'blue' ton, centralization of x-ray examination and quality of apparatus, are discussed. From the Government primarily a constraint setting policy is expected, in which rule-giving with respect to quality of education and apparatus is highly important. A stimulation of inter-collegial consulting may be expected, in particular in financial sense. A permission policy has to be managed, which ensures centralization of apparatus and centrally performance of x-ray examination as much as possible. Finally warning is given for the effects of excessive fear for radiation which causes refraining of medical necessary examination. The various risk have to be weighed up

  3. Totally Carrying out Zero Defects Quality Control

    Institute of Scientific and Technical Information of China (English)

    ZhangQingwei; CASCPresident

    2004-01-01

    Editorial note: On March 22,1992 the launch of LM-2E launch vehicle with an Australian satellite was terminated. A piece of 0.15 milligram aluminum redundance led to the malfunction of the program distributor, which caused the emergency cutoff after 7 seconds of the ignition of the rocket. To bear in mind the painful lesson, China Aerospace Corporation set out March 22 to be “Space Quality Day” in 1994.

  4. Quality control of CANDU6 fuel element in fabrication process

    International Nuclear Information System (INIS)

    To enhance the fine control over all aspects of the production process, improve product quality, fuel element fabrication process for CANDU6 quality process control activities carried out by professional technical and management technology combined mode, the quality of the fuel elements formed around CANDU6 weak links - - end plug , and brazing processes and procedures associated with this aspect of strict control, in improving staff quality consciousness, strengthening equipment maintenance, improved tooling, fixtures, optimization process test, strengthen supervision, fine inspection operations, timely delivery carry out aspects of the quality of information and concerns the production environment, etc., to find the problem from the improvement of product quality and factors affecting the source, and resolved to form the active control, comprehensive and systematic analysis of the problem of the quality management concepts, effectively reducing the end plug weld microstructure after the failure times and number of defects zirconium alloys brazed, improved product quality, and created economic benefits expressly provided, while staff quality consciousness and attention to detail, collaboration department, communication has been greatly improved and achieved very good management effectiveness. (authors)

  5. Quality control of solidified intermediate and highly active wastes

    International Nuclear Information System (INIS)

    It is shown that quality control on processed radioactive waste (for temporary storage) is an important component in an extensive waste-quality safety program. The quality controls should follow the following steps: determination of container dimensions and weight; determination of surface contamination; calorimetry for measurement of heat production of highly active waste; determination of gamma flux and temperature distribution on the container surface; and neutron measurement for calculating the transuranic elements content. The various methods are presented and discussed. A possible control system in an intermediate layer is presented. (A.N.K.)

  6. Internal control reporting and accounting quality : Insight "comply-or-explain" internal control regime

    OpenAIRE

    Cao Thi Thanh, Huyen; Cheung, Tina

    2010-01-01

    Nowadays, there exist two reporting regimes, rules-based and principle-based (comply-or-explain). In the rules-based environment, researchers have studied the relationship between internal control quality and accounting quality. Prior studies have suggested that reports on internal control are an effective way for investors to evaluate the quality of the firm‟s internal control. By having a sound system of internal control, it creates reliance upon the firm‟s financial reporting. Therefore, t...

  7. Optimizing prostate biopsy for repeat transrectal prostate biopsies patients

    Institute of Scientific and Technical Information of China (English)

    Xiaojun Deng; Jianwei Cao; Feng Liu; Weifeng Wang; Jidong Hao; Jiansheng Wan; Hui Liu

    2014-01-01

    Objective:Diagnosis of patients with negative prostate biopsy and persistent suspicion of prostate cancer re-mains a serious problem. In this study, we investigated the application of optimizing prostate biopsy for patients who need repeat prostate biopsy. Methods:In this prospective, non-randomized phase-I clinical trial, the prostate cancer detection rate of initial detection scheme was compared with optimizing prostate biopsy scheme. The number of punctures of initial detection scheme was the same as that of optimizing prostate biopsy scheme. The puncture direction of optimizing prostate biopsy was a 45° angle to the sagittal plane from front, middle, and back. The two cores from each lateral lobe were horizontal y inwardly inclined 45°. Results:A total of 45 patients with initial negative biopsy for cancer were received the optimizing prostate biopsy scheme. The cancer detection rate was 17.8%(8/45), and prostate intraepithelial neoplasm (PIN) was 6.7%(3/45). The pa-tients receiving repeat transrectal prostate biopsies were pathological y diagnosed as lower Gleason grade prostate cancers. Conclusion:The cancer detection rate of repeat biopsy prostate cancer is lower than that of initial biopsy. Our study showed that the optimizing prostate biopsy is important to improve the detection rate of repeat transrectal prostate biopsies patients.

  8. Dosimetry and quality control in radiodiagnosis

    International Nuclear Information System (INIS)

    This work deals with physics of radiodiagnosis. In a first part a study of the characteristics of different kinds of radiological equipments and a quality assurance of some of them (standard radiography, coronarography and computed tomography) have been performed. The second part deals with patient irradiation. After a bibliographic study of radiodiagnosis dosimetry, two kinds of dosimetric measures have been made: ''in vitro'' measures, using a phantom, that had allowed to calibrate the equipment and to improve the individual irradiation card, and ''in vivo'' measures. For the first types of measures ionization chambers, have been used for the second thermoluminescent dosimeters

  9. Implementation of quality control systematics for personnel monitoring services

    International Nuclear Information System (INIS)

    The implementation of statistical quality control techniques used in industrial practise is proposed to dosimetric services. 'Control charts' and 'sampling inspection' are adapted respectively for control of measuring process and of dose results produced in routine. A chapter on Radiation Protection and Personnel Monitoring was included. (M.A.C.)

  10. European quality assurance and quality control for cut-off walls and caps

    International Nuclear Information System (INIS)

    Cut-off walls and caps both may be seriously compromised by small areas of substandard materials or work. Quality assurance/quality control is therefore of crucial importance and the paper sets out the issues that need to be addressed when designing a quality plan for a containment. Consideration is given to the purpose of the containment, the parameters to be controlled, specifications and standards and tests on raw and manufactured materials and on the in-situ containment. It is not the purpose of the paper to give detailed test procedures but rather to identify the questions that must be answered to develop a quality plan

  11. A Quality Analysis of Randomized Controlled Trials about Erectile Dysfunction

    OpenAIRE

    Chung, Jae Hoon; Lee, Jeong Woo; Jo, Jung Ki; Kim, Kyu Shik; Lee, Seung Wook

    2013-01-01

    Purpose A low quality clinical trial could produce errors, and these errors could, in turn, distort the results of the clinical trial. To avoid applying distorted results of trials clinically, a quality analysis of clinical trials is needed. Materials and Methods We selected randomized controlled trials (RCTs) about erectile dysfunction (ED) conducted in Korea using Medline and KoreaMed. Quality assessment of selected RCTs was performed using three assessment tools (Jadad scales, van Tulder s...

  12. Quality evaluation of controlled clinical information service trials.

    OpenAIRE

    Balas, E A; Austin, S. M.; Brown, G.D.; Mitchell, J. A.

    1993-01-01

    Randomized controlled clinical trials are increasingly accepted as tools of computer technology assessment and, therefore, quality evaluation of trials has great theoretical and practical significance. The purpose of this study was to assist the design of evaluation studies and synthesis of published results by developing and validating an easy-to-use quality scoring method. The development of the new scoring system was based on the available quality evaluation methods and the analysis of 19 ...

  13. Quality control of a herb extract using PTR-MS

    Science.gov (United States)

    Jaksch, D.; Hartungen, E.; Mikoviny, T.; Abel, G.; Märk, T. D.

    2004-12-01

    We have developed an objective method for the determination of a herb extract's quality based on headspace measurements by proton-transfer-reaction mass spectrometry (PTR-MS); this quality was checked by a sensory analysis until now. This novel method enables the company [`]Bionorica' to ensure that they are only selling high-quality products and therefore avoid complaints of the customer. The method could be also used for controlling and optimising the production process.

  14. Quality control activities in the environmental radiology laboratory

    International Nuclear Information System (INIS)

    During the last twenty years many analytical laboratories have implemented quality assurance systems. A quality system implementation requires documentation of all activities (technical and management), evaluation of these activities and its continual improvement. Implementation and adequate management of all the elements a quality system includes are not enough to guarantee quality of the analytical results generated at a time. That is the aim of a group of specific activities labelled as quality control activities. The Laboratori de Radiologia Ambiental (Environmental Radiology Laboratory; LRA) at the University of Barcelona was created in 1984 to carry out part of the quality control assays of the Environmental Radiology Monitoring Programs around some of the Spanish nuclear power plants, which are developed by the Servei Catala d'Activitats Energetiques (SCAR) and the Consejo de Seguridad Nuclear (CSN), organisations responsible for nuclear security and radiological protection. In these kind of laboratories, given the importance of the results they give, quality control activities become an essential aspect. In order to guarantee the quality of its analytical results, the LRA Direction decided to adopt the international standard UNE-EN ISO/IEC 17025 for its internal quality system and to accreditate some of the assays it carries out. In such as system, it is established, the laboratory shall monitor the validity of tests undertaken and data shall be recorded in such a way that trends are detectable. The present work shows the activities carried out in this way by the LRA, which are: Equipment control activities which in the special case of radiochemical techniques include measurement of backgrounds and blanks as well as periodical control of efficiency and resolution. Activities to assure the specifications settled by method validation, which are testing of reference materials and periodical analysis of control samples. Evaluation of the laboratory work quality

  15. Quality Changes of Frozen Meat During Storage and Control Measures

    Institute of Scientific and Technical Information of China (English)

    DU Jiangping

    2010-01-01

    The frozen is a common method of meat storage, generally applications in meat industrial. However, the quality of meat still have taken place changes even in the low temperature, This article discussion on the changes of frozen meat quality during freezing storage, and give the corresponding control measures.

  16. Academic Quality Control in Nigerian Universities: Exploring Lecturers' Perceptions

    Science.gov (United States)

    Obiekezie, E. O.; Ejemot-Nwadiaro, R. I.; Essien, M. I.; Timothy, A. Essien

    2014-01-01

    The level of job performance, international comparability and competitiveness of Nigerian university graduates are burning issues. Consequently, the academic quality of Nigerian universities has come under severe criticism. Since university lecturers are key players in quality control in universities, this study explored their perceptions of…

  17. 21 CFR 211.22 - Responsibilities of quality control unit.

    Science.gov (United States)

    2010-04-01

    ..., closures, in-process materials, packaging material, labeling, and drug products, and the authority to..., closures, packaging materials, in-process materials, and drug products shall be available to the quality... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Responsibilities of quality control unit....

  18. Experience in quality control of PET with source of germanium

    International Nuclear Information System (INIS)

    In our hospital, the quality guarantee program in Nuclear Medicine was implemented in 2007. In the section on control quality figure, along with monthly measures, daily tests of sensitivity and uniformity of a Siemens PET-CT Bio graph 6 with a cylindrical Ge68 source. In this work the results of these monthly tests between 2010 and 2012. (Author)

  19. Quality Assurance and Control in Laboratory using Neutron Activation Analysis

    International Nuclear Information System (INIS)

    In accordance with the increment of international trade associated with the worldwide globalization, the importance of quality assurance and control for the commodity produced from one's own country has been stressed. ISO (International Organization for Standards) defines quality control as 'the operational techniques and activities that are used to fulfill the requirements for quality'. Since 1996, the HANARO research reactor in the Korea Atomic Energy Research Institute has been operated thereafter initial critical operation on April 1995. Neutron activation analysis system and applied techniques which is one of a nuclear analytical technologies using reactor neutrons has been developed for user's supporting and the establishment of the quality system for a measurement and analysis, testing and inspection was implemented successfully. On the basis of the qualified NAA system, the test and measurement of more than 1500 samples which is requested from 30 organizations including industrial companies, universities and institutes carried out in NAA laboratory annually. Moreover, as the goal of mutual recognition agreement (MRA) which can be removed a technical barrier in international trade, the objectivity and the confidence of analytical quality in NAA laboratory became established through the installation of international accreditation system by implementing analytical quality system in accordance with international standards in 2001. The aim of the report was to summarize the technical management of introduction, methods and the results for a quality control and assurance which should be performed in NAA technique using the HANARO research reactor. The report will help building up effective quality control strategy in the future

  20. Quality control in electronic portal imaging devices

    International Nuclear Information System (INIS)

    Purpose/Objective: Pitfalls in the electronic portal imaging routine demonstrate the necessary of a quality assurance program. The aim of this study is to evaluate the limits of various commercially available video based systems in the recognition of mistakes made when positioning radiation fields. In addition, the time stability of the systems was investigated. The parameters used were spatial resolution, contrast difference and geometric distortion. Material and Methods: A special phantom was designed consisting of a box filled with silicon and containing one metal plate with a hole of 20 cm diameter, one metal plate containing small holes of different diameters (0.5 to 10 mm) and step wedges of metal and cork. The images of the big hole provide information about the degree of distortion, those of the small holes, about spatial resolution and those of the step wedges, about contrast difference. The energy of the X-rays was 6, 10, 15 and 25 MeV. Hardcopies on both paper and film were investigated as well as the presentation on the screen. Different available image processing programs were used. The quality standard was given by a port film with copper/plastic cassette exposed with 6 MeV X-rays. Results: The minimum detail diameter which could be delineated with all systems was about 1mm, irrespective of the X-ray's energy. The minimum contrast was found to be depending on the system as well as on the special parameters of the imaging processing method applied. In some cases, the geometric distortion was up to 20%. We observed cloud-like artefacts on the paper hardcopies, which destroyed the detail informations. Conclusion: The quality of the electronic portal imaging devices is lower than that of conventional port films. The comparison of the systems shows differences in detail contrast but not in the spatial resolution. In some cases, significant degrees of distortion were found. It is necessary to have a check program in order to evaluate the differences between

  1. Performance Evaluation Model for Product Quality Control of Vegetable Cooperatives

    Directory of Open Access Journals (Sweden)

    Li Qin

    2013-08-01

    Full Text Available The purpose of this study is to investigate the product quality control performance of vegetable cooperatives in China, using Heilongjiang province as a case. This study applies fuzzy integral theory to develop a comprehensive evaluation model and analyzes the product quality control performance of the vegetable cooperatives. The results show that the performance of vegetable cooperatives in the production process is the highest. That is, vegetable cooperatives have important effect on the performance of product quality control mainly in the production process. Through the large-scale operation and the implementation of standardized production, vegetable cooperatives can effectively transform the decentralized production into the unified production. To exert the role of vegetable cooperatives in the product quality control, the incentive systems and the financial support policies should be improved and actively implement the brand strategy.

  2. Quality controls of radiopharmaceuticals used in nuclear medicine

    International Nuclear Information System (INIS)

    Chromatographic quality controls for Tc-99m; In-113m; I-131; Tl-201 and Ga-67 radiopharmaceuticals are described. Moreover, a chromatographic system which allows to separate different radiopharmaceuticals from In-113m is pointed out. (author)

  3. Research Ship Southern Surveyor Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Southern Surveyor Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and...

  4. NOAA Ship Bell M. Shimada Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Bell M. Shimada Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  5. NOAA Ship Okeanos Explorer Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Okeanos Explorer Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  6. Research Ship Atlantis Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Atlantis Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  7. Research Ship Kilo Moana Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Kilo Moana Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  8. Research Ship Robert Gordon Sproul Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Robert Gordon Sproul Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and...

  9. NOAA Ship Oregon II Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Oregon II Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  10. Research Ship T. G. Thompson Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship T. G. Thompson Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  11. NOAA Ship Oscar Dyson Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Oscar Dyson Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  12. Research Ship Tangaroa Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Tangaroa Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  13. NOAA Ship David Starr Jordan Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship David Starr Jordan Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  14. NOAA Ship Hi'ialakai Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Hi'ialakai Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  15. NOAA Ship Rainier Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Rainier Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  16. Research Ship Atlantic Explorer Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Atlantic Explorer Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and...

  17. NOAA Ship Nancy Foster Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Nancy Foster Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  18. Research Ship New Horizon Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship New Horizon Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  19. NOAA Ship Ronald Brown Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Ronald Brown Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  20. Research Ship Nathaniel B. Palmer Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Nathaniel B. Palmer Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and...

  1. Research Ship Laurence M. Gould Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Laurence M. Gould Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and...

  2. Research Ship Aurora Australis Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Aurora Australis Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  3. Research Ship Healy Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Healy Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  4. NOAA Ship Delaware II Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Delaware II Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  5. NOAA Ship Gordon Gunter Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Gordon Gunter Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  6. Research Ship Melville Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Melville Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  7. Research Ship Oceanus Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Oceanus Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  8. NOAA Ship Oscar Elton Sette Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Oscar Elton Sette Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  9. NOAA Ship Ka'imimoana Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Ka'imimoana Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  10. NOAA Ship Pisces Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Pisces Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  11. Research Ship Roger Revelle Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Roger Revelle Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  12. NOAA Ship Fairweather Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Fairweather Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  13. NOAA Ship Miller Freeman Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Miller Freeman Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  14. Research Ship Knorr Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Knorr Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  15. NOAA Ship Henry B. Bigelow Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Henry B. Bigelow Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  16. Quality control system response to stochastic growth of amyloid fibrils.

    Science.gov (United States)

    Pigolotti, Simone; Lizana, Ludvig; Otzen, Daniel; Sneppen, Kim

    2013-05-01

    We introduce a stochastic model describing aggregation of misfolded proteins and degradation by the protein quality control system in a single cell. Aggregate growth is contrasted by the cell quality control system, that attacks them at different stages of the growth process, with an efficiency that decreases with their size. Model parameters are estimated from experimental data. Two qualitatively different behaviors emerge: a homeostatic state, where the quality control system is stable and aggregates of large sizes are not formed, and an oscillatory state, where the quality control system periodically breaks down, allowing for formation of large aggregates. We discuss how these periodic breakdowns may constitute a mechanism for the development of neurodegenerative diseases. PMID:23524241

  17. Descriptive study of the quality control in mammography; Estudio descriptivo del control de calidad en mamografia

    Energy Technology Data Exchange (ETDEWEB)

    Gaona, E.; Perdigon C, G.M.; Casian C, G.A.; Azorin N, J.; Diaz G, J.A.I.; Arreola, M. [UAM, Xochimilco 14000 Mexico D.F. (Mexico)

    2005-07-01

    The goal of mammography is to provide contrast between a lesion that is possible residing within the breast and normal surrounding tissue. Quality control is essential for maintaining the contrast imaging performance of a mammography system and incorporate tests that are relevant in that they are predictive of future degradation of contrast imaging performance. These tests will also be done at frequency that is high enough to intercept most drifts in quality imaging or performance before they become diagnostically significant. The quality control study has as objective to describe the results of the assessment of quality imaging elements (film optical density, contrast (density difference), uniformity, resolution and noise) of 62 mammography departments without quality control program and comparison these results with a mammography reference department with a quality control program. When comparing the results they allow seeing the clinical utility of to have a quality control program to reduce the errors of mammography interpretation. (Author)

  18. Recent advances in bone marrow biopsy pathology

    OpenAIRE

    van der Walt, Jon

    2009-01-01

    The second quarter of 2009 saw steady advances in bone marrow biopsy (BMB) pathology. The following publications are a personal selection of the highlights. Quality issues in diagnostic immunohistochemistry for BMB have largely been ignored in external quality assurance programmes, and this issue is highlighted. In other areas, publications reflecting advances in flow cytometry and aspirate morphology are discussed where translation to the BMB is possible. Classifications undergo constant cha...

  19. Suggestion for improvement of PET quality control tests in Brazil

    International Nuclear Information System (INIS)

    Nowadays nuclear medicine has a considerable importance among the other medical specialties. This medical specialty utilizes high-tech equipment for imaging in the diagnosis, obtaining information on the clinical functionality of organs and systems of the human body through the use of radioisotopes . In view of the importance of guaranteeing the image quality in SPECT and PET systems, enabling patients not repeat exams due to lack of quality control of equipment used in nuclear medicine, this paper aims to present a possible suggestion to update the quality control tests needed for quality assurance of nuclear medicine services. They were considered the requirements of the National Commission of Nuclear Energy (CNEN) and the National Health Surveillance Agency (ANVISA) in Brazil. The minimum requirements to be defined for inclusion of quality control tests on PET in the standard CNEN are extremely important because they will guide the evaluation of PET systems, determining the quality control tests to be performed. And those tests for PET will be a regulatory requirement by the CNEN and ANVISA. As the National Health Surveillance Agency has already publication of RDC 38 with recommendations for services of nuclear medicine. This study will continue with evaluation of PET systems and presenting the tests of quality control with additional objects and simulators to ensure safety in PET systems have not standardized in nuclear medicine services in Brazil. (author)

  20. Preparation and quality control of ECD kit

    International Nuclear Information System (INIS)

    ECD Kit for brain imaging after labeling with technetium 99m was prepared according to an optimum conditions, Each vial contains 1 mg of ECD and 0.155 mg of stannous chloride anhydrous SnCl2, 24 mg of Mannitol and 0.5 mg of Na2Ca EDTA, The prepared kit showed high quality satisfying the requirements of international pharmacopoeias from the points of physical, chemical, radiochemical and biological purities, and its validity for human injection. And the labeling yield exceeded 95 % with average value of about 97.63 ± 0.89% for 2mCi /2ml radioactivity , This study also showed that each vial content can be labeled with maximum activity of 99mTc of about 50 mCi (Authors)

  1. The CEA contribution to quality control

    International Nuclear Information System (INIS)

    The Commissariat a l'Energie Atomique has developed original methods and techniques for testing delicate components of the primary circuit of pressure water reactors. These techniques make use of a very wide range of non destructive testing methods: Eddy currents, particularly multiple frequencies, for testing steam generator tubes, gudgeon and other pins focused ultrasonics for testing all the welds of the reactor vessel and its cover plate, mixed welds of steam vessels and generators, low welds of the pressurizer and gudgeon pins from the inside. On site use is effected with specific machines intended either for inspecting the tube bundles of steam generators under the responsibility of INTERCONTROLE Co., or for the complete examination of the reactor vessel by mixed CEA/INTERCONTROLE crews under the responsibility of the CEA. All these operations are subjected to a programme of quality assurance that provides the guaranty of execution complying with the procedures in force

  2. Development of Quality Control Procedures for Lepidoptera

    Science.gov (United States)

    Lepidopteran species are among the most destructive insect pests throughout the world. The sterile insect technique (SIT), within an area-wide integrated pest management (AW-IPM) approach, has proven to be a valuable tactic for controlling and eradicating important moth pests. Improving laboratory...

  3. Quality control of radiopharmaceuticals. Pt. 2

    International Nuclear Information System (INIS)

    In this article, activities of the Federal Health Office are reported: a) Dictionary-like compilations of methods for control of radiochemical impurities; b) Development of analytical separation and determination procedures as well as measuring methods for the quantification of impurities; c) Market analysis of commercially available radiopharmaceuticals. (RB)

  4. Quality control of injection moulded micro mechanical parts

    DEFF Research Database (Denmark)

    Gasparin, Stefania; Tosello, Guido; Hansen, Hans Nørgaard;

    2009-01-01

    Quality control of micro components is an increasing challenge. Smaller mechanical parts are characterized by smaller tolerance to be verified. This paper focuses on the dimensional verification of micro injection moulded components selected from an industrial application. These parts are measured...... using an Optical Coordinate Measuring Machine (OCMM), which guarantees fast surface scans suitable for in line quality control. The uncertainty assessment of the measurements is calculated following the substitution method. To investigate the influence parameters in optical coordinate metrology two...

  5. Using statistical quality control techniques to monitor blood glucose levels.

    OpenAIRE

    Oniki, T. A.; Clemmer, T. P.; Arthur, L. K.; Linford, L. H.

    1995-01-01

    Continuous Quality Improvement techniques developed in industry are increasingly being applied to the medical field. Statistical process control charts are a CQI technique aimed at monitoring a process and its variability. At our hospital, statistical quality control charts are being constructed from laboratory blood glucose measurements of patients receiving enteral or parenteral nutrition. The charts will be used to monitor glucose levels, reveal variations, and illustrate the effects of ne...

  6. Biofuel quality control by portable XRF-analyser

    OpenAIRE

    Golubev, Vitaly

    2015-01-01

    The objective of this thesis project was to find out feasibility of using a handheld XRF-analyser in solid biofuel quality control, particularly for recovered wood. Global biomass supply is estimated to grow rapidly, creating demand for automatic quality control systems. X-ray fluorescent technology brings about quick, accurate and non-destructive elemental analysis. Recovered wood fuel is challenging for combustion due to high levels of contaminants. During this work a list of challenging ch...

  7. Preserving organelle vitality: peroxisomal quality control mechanisms in yeast

    OpenAIRE

    Aksam, Eda Bener; de Vries, Bart; van der Klei, Ida J.; Kiel, Jan A. K. W.

    2009-01-01

    Cellular proteins and organelles such as peroxisomes are under continuous quality control. Upon synthesis in the cytosol, peroxisomal proteins are kept in an import-competent state by chaperones or specific proteins with an analogous function to prevent degradation by the ubiquitin-proteasome system. During protein translocation into the organelle, the peroxisomal targeting signal receptors (Pex5, Pex20) are also continuously undergoing quality control to enable efficient functioning of the t...

  8. Quality control and quality assurance in individual monitoring of ionising radiations

    International Nuclear Information System (INIS)

    This paper describes the programmes and approaches that are to be considered in developing and introducing quality assurance and quality control procedures in individual monitoring services. Quality assurance and quality control in individual monitoring services are essential to maintain quality and are of increasing importance in order to meet the requirements of national regulations and international standards and guidelines. It is recommended here that all organisations offering individual monitoring services should run their services based on the principles of Quality System as given in the European Standard EN45001 and maintain a property resources QA/QC programme as an integral part of their operations. All aspects of QA/QC in individual monitoring services starting from the initial selection, installation, calibration, and operation to the final products including dose reporting, dose record keeping, dealing with customers' complaints and product liability issues have been discussed. (Author)

  9. Production process and quality control for the HTTR fuel

    International Nuclear Information System (INIS)

    Development of the production and inspection technology for High Temperature Engineering Test Reactor (HTTR) fuel has been carried out by cooperative work between Japan Atomic Energy Research Institute (JAERI) and Nuclear Fuel Industries, Ltd (NFI). The performance and the quality level of the developed fuel are well established to meet the design requirements of the HTTR. For the commercial scale production of the fuel, statistical quality control and quality assurance must be carefully considered in order to assure the safety of the HTTR. It is also important to produce the fuel under well controlled process condition. To meet these requirements in the production of the HTTR fuel, a new production process and quality control system is to be introduced in the new facilities. The main feature of the system is a computer integrated control system. Process control data at each production stage of products and semi-products are all gathered by terminal computers and processed by a host computer. The processed information is effectively used for the production, quality and accountancy control. With the aid of this system, all the products will be easily traceable from starting materials to final stages and the statistical evaluation of the quality of products becomes more reliable. (author). 8 figs

  10. Quality control in computed tomography X-ray scanners

    International Nuclear Information System (INIS)

    Practical methods of estimating computed tomography X-ray scanner imaging performance treat the scanner as a black box, the measurements usually being non-invasive. The performance of individual components or groups of components within the system is not usually measured. The digital nature of the imaging process allows direct numerical assessment of the actual imaging parameters. This approach is used for type and acceptance testing as well as quality control, the type and acceptance tests providing the baseline for subsequent quality control measurements. The usual X-ray imaging parameters of noise, resolution and dose can all be used for quality control purposes, but the relative emphasis between these parameters will differ when compared with type or acceptance testing. Other simple measurements may be of equal use. All manufacturers suggest quality control protocols of varying complexity using a wide range of phantom designs. Where quality control is undertaken routinely, it is usually the manufacturer's protocols that are followed. It is pertinent to ask whether the quality control measurements currently suggested are necessary and/or sufficient. (author)

  11. Hepatic pseudolesion after biopsy

    International Nuclear Information System (INIS)

    We report the diagnosis and differential diagnosis of a hepatic pseudolesion due to percutaneous liver biopsy in a 30-year-old female patient with known chronic hepatitis C and renal insufficiency. In the course of transplant preparation, an abdominal spiral-CT examination pre and post i.v.-contrast injection as well as an angiography with CT-hepaticography and CT-portography were performed. In these examinations a 1 cm, hepatocellular-carcinoma mimicking liver lesion was found; it was hypodense in the CT-portography and showed a marked enhancement in the CT-hepaticography. This 'pseudolesion', which was supposed to be due to the liver biopsy, resolved spontaneously. (orig.)

  12. Celiac Disease Diagnosis: Endoscopic Biopsy

    Science.gov (United States)

    ... This is done in a procedure called a biopsy: the physician eases a long, thin tube called ... the tissue using instruments passed through the endoscope. Biopsy of the small intestine is the only way ...

  13. Bone Marrow Aspiration and Biopsy

    Science.gov (United States)

    ... Global Sites Search Help? Bone Marrow Aspiration and Biopsy Share this page: Was this page helpful? Also ... Examination Formal name: Bone Marrow Aspiration; Bone Marrow Biopsy Related tests: Complete Blood Count ; WBC Differential ; Reticulocyte ...

  14. Gram stain of tissue biopsy

    Science.gov (United States)

    ... ency/article/003453.htm Gram stain of tissue biopsy To use the sharing features on this page, please enable JavaScript. Gram stain of tissue biopsy test involves using crystal violet stain to test ...

  15. Experience with ISO quality control in assisted reproductive technology.

    Science.gov (United States)

    Alper, Michael M

    2013-12-01

    Assisted reproductive technology (ART) programs are complex organizations requiring the integration of multiple disciplines. ISO 9001:2008 is a quality management system that is readily adaptable to an ART program. The value that ISO brings to the entire organization includes control of documents, clear delineation of responsibilities of staff members, documentation of the numerous processes and procedures, improvement in tracking and reducing errors, and overall better control of systems. A quality ART program sets quality objectives and monitors their progress. ISO provides a sense of transparency within the organization and clearer understanding of how service is provided to patients. Most importantly, ISO provides the framework to allow for continual improvement. PMID:24112531

  16. Production And Quality Control Of Radiopharmaceutical 18F-FDG

    International Nuclear Information System (INIS)

    18F-FDG is a radiopharmaceutical for imaging diagnosis with PET/CT in Nuclear Medicine. Criteria of injection pharmaceuticals are the highest standards. So, quality assurance and quality control must be followed very strictly. The selection of the procedure for 18F-FDG has based on several criteria: high chemical efficiency, short synthesis time, toxic component free and etc. The quality control of 18F-FDG consist many fields such as: nuclear physic (nuclear purity), radiochemistry (radionuclear purity, radiochemical purity), chemistry (chemical purity), radiation measurement (half life), microbiology (pyrogen, endotoxin), etc. which is following USP, BP or EP. (author)

  17. Control measures for NDE and quality in project construction

    International Nuclear Information System (INIS)

    Projects are constructed with huge investments in money, time and effort and therefore it is essential that they perform well during the intended life period. The reliability so expected can only be ensured by achieving the desired quality in construction. Quality mainly depends upon the effective controlling of materials used in construction, work procedures adopted, personnel performing the important functions and work environment and also ensuring proper documentation. The above fact has been well recognized during construction of the Project at Kalpakkam under Dept. of Atomic Energy. The control measures which have been designed and successfully implemented for achieving the quality are presented. (author)

  18. Quality control of scintillation cameras (planar and SPECT)

    International Nuclear Information System (INIS)

    Regular quality control is one of the corner stones of nuclear medicine and a prerequisite for adequate diagnostic imaging. Many papers have been published on quality control of planar and SPECT imaging system up to now, however only minor attenuation has been given to the assessment of the performance of imaging systems. In this research we are going to discuss a comprehensive set of test procedures including regular quality control. Our purpose is to go through analysis of the methods and results then to test our hypothesis which state that there is strong relationship between regular and proper evaluation of quality control and the continuity of better medical services in nuclear medicine department. The selection of the tests is discussed and the tests are described, then results are presented. In addition action thresholds are proposed. The quality control tests can be applied to systems with either a moving detector or a moving image table, and to both detector with a large field of view and detectors with a small field of view. The tests presented on this research do not required special phantoms or sources other than those used for quality control of stationary gamma camera and SPECT. They can be applied for acceptance testing and for performance testing in a regular quality assurance program. The data has been evaluated based on me diso software in comparing with IAEA expert software and system specification within the reference values. Our final results confirm our hypothesis, there are some comments about the characteristics and performance of this system that being observed and solved, then a departmental protocol for routine quality control (Q.C) has being established.(Author)

  19. Quality control in diagnostic mammography: myths, realities and their importance in the final image quality

    International Nuclear Information System (INIS)

    Mammography is the most used tool for early detection of breast cancer and reduce mortality from this cause. Studies with ionizing radiation it is important that be justified and provide a quality image to make the diagnosis, to get more benefits and fewer risks. The problem is the difficult to obtain an image of the breast. Therefore, the commitment to quality mammography is to maximize the contrast, definition, resolution and reliability, thus minimizing noise and dose. A mammogram performed without quality don't detect early breast cancer and the study doesn't have sense. Quality mammography requires trained and experienced staff, modern equipment and in good conditions, correct positioning, right technical factors and appropriate viewing conditions. In addition, quality programs are required to reach to ensure quality, control in testing techniques and image quality. (author)

  20. Quality control and quality assurance of micromegas readout boards for the ATLAS New Small Wheel

    CERN Document Server

    Nanda, Amit

    2016-01-01

    The resistive anode boards of the Micromegas detectors for ATLAS NSW upgrade, will be produced in industries. The anode boards will be thoroughly evaluated at CERN following a detailed quality control and quality assurance (QA/QC) procedure. The report describes thoroughly the procedures and the design of a small QC tool for easier measurements of electrical properties of the readout boards.

  1. The process of managerial control in quality improvement initiatives.

    Science.gov (United States)

    Slovensky, D J; Fottler, M D

    1994-11-01

    The fundamental intent of strategic management is to position an organization with in its market to exploit organizational competencies and strengths to gain competitive advantage. Competitive advantage may be achieved through such strategies as low cost, high quality, or unique services or products. For health care organizations accredited by the Joint Commission on Accreditation of Healthcare Organizations, continually improving both processes and outcomes of organizational performance--quality improvement--in all operational areas of the organization is a mandated strategy. Defining and measuring quality and controlling the quality improvement strategy remain problematic. The article discusses the nature and processes of managerial control, some potential measures of quality, and related information needs. PMID:10138526

  2. Quality control of environmental radiation monitoring process

    International Nuclear Information System (INIS)

    This report summarizes for the period (January/2003 to September 2003) the analytical results of the Environmental Monitoring Program- Centro de Desenvolvimento da Tecnologia Nuclear - CDTN. A statistical treatment using control graphs for periodicity and tendency analysis according to temporal variation is also carried out. Moreover, a comparison of radioactive and stable elements concentrations with the derived and intake limits for ingestion and inhalation recommended by Comissao Nacional de Energia Nuclear, Fundacao Estatual do Meio Ambiente (FEAM) e Instituto Brasileiro do Meio Ambiente (IBAMA) is performed. The results are compliant with those recommended by the legislation. (author)

  3. Quality control and quality assurance in radiation medicine in the Republic of Moldova

    International Nuclear Information System (INIS)

    Quality Health care results from translating fundamental bench discoveries and making them available to patients. During the past decade, 'molecular imaging' has emerged both as a new tool/technology and as a research and clinical discipline. Molecular imaging is an interdisciplinary approach involving biologist, physicist, physicians, mathematicians, radio chemists and other specialists who have joined forces for better understanding and visualizing of both normal physiological processes and the molecular processes preceding the morphological manifestations of disease in vivo. It is interesting to note, that despite major advances in imaging technology, cancer mortality has remained largely unchanged over the last three decades. Imaging has thus far enabled us to look through a magnifying glass at disease processes but has failed to dramatically influence disease outcomes. Emerging data suggest that molecular PET imaging is about to change this situation. Quality assurance is based on monitoring, measuring, evaluation, verification and recording of quantities, parameters and facts significant from the point of view of Radiation Protection. Quality assurance programs shall be established that provide, as appropriate: adequate assurance that the specified requirements relating to protection and safety are satisfied and quality control mechanisms and procedures for reviewing and assessing the overall effectiveness of protection and safety. The Republic of Moldova with the support of the International Atomic Energy Agency perform the quality assurance and quality control procedures in the frame of the Technical Cooperation Regional Projects RER-6-012 ''Quality Assurance and Quality Control in Radiation Oncology'', and RER-6-011 'Thematic Program on Nuclear Medicine'. The Ministry of Health and Social Protection carry out the National Project 'Ensuring Radiation Safety and Protection of the Patients' the principal goal being the Quality Assurance and Quality Control in

  4. Percutaneous Transcatheteral Biliary Biopsy (PTBB)

    OpenAIRE

    Kim, Dae Ghon; Song, Suck Hyun; Jang, Hyun Cheol; Kim, Jung Gweon; Ahn, Hong Suck; Ahn, Deuk Soo; Kim, Jong Soo; Han, Yeung Min

    1989-01-01

    In two patients with obstructive jaundice, percutaneous transhepatic cholangiography (PTC) and percutaneous transhepatic biliary drainage (PTBD) were performed. During PTBD, the percutaneous transcatheteral biliary biopsy (PTBB) with the biopsy forceps of the gastrofiberscope was performed through the biliary stent catheter. Biopsy specimens were successfully obtained and histopathologic findings were satisfactory in both cases.

  5. Research review: Indoor air quality control techniques

    International Nuclear Information System (INIS)

    Techniques for controlling the concentration of radon, formaldehyde, and combustion products in the indoor air are reviewed. The most effective techniques, which are generally based on limiting or reducing indoor pollutant source strengths, can decrease indoor pollutant concentrations by a factor of 3 to 10. Unless the initial ventilation rate is unusually low, it is difficult to reduce indoor pollutant concentrations more than approximately 50% by increasing the ventilation rate of an entire building. However, the efficiency of indoor pollutant control by ventilation can be enhanced through the use of local exhaust ventilation near concentrated sources of pollutants, by minimizing short circuiting of air from supply to exhaust when pollutant sources are dispersed and, in some situations, by promoting a displacement flow of air and pollutants toward the exhaust. Active air cleaning is also examined briefly. Filtration and electrostatic air cleaning for removal of particles from the indoor air are the most practical and effective currently available techniques of air cleaning. 49 refs., 7 figs

  6. [Our experience with outside laboratory quality control].

    Science.gov (United States)

    Dochev, D; Arakasheva, V; Nashkov, A; Tsachev, K

    1979-01-01

    The results from the national outside laboratory qualitative control of the clinical diagnostic laboratory investigations for the period September 1975 -- May 1977 were described. The following interlaboratory discrepancy was found on base of a systematic analysis of the data from the last two ring-like check-ups, November 1976 and May 1977, exressed by the variation coefficient (V.C. %); total protein, sodium, potassium and chlorides -- under 10%; cholesterol, urea and total fats -- between 10 and 20%; calcium, phosphorus, iron and creatinine -- over 20%. The highest per cent of admissible results are found with total protein -- to 85%; cholesterol -- to 70.38%; glucosa -- to 73.17%, urea -- to 69.23%, potassium -- to 59.46%, chlorides -- to 57.9%. With sodium, phosphorus, calcium, iron creatinine and uric acid the "admissibility" fluctuates about or under 50 per cent. The values of the qualitative-control indices discussed are comparable with the values obtained from them in the interlaboratory comparisons of other countries. PMID:494628

  7. Quality control of cemented waste forms

    Energy Technology Data Exchange (ETDEWEB)

    Slate, L.J.

    1994-12-31

    To insure that cemented radwaste remains immobilized after disposal, certain standards have been set in Europe by the Commission of the European Communities. One such standard is compressive strength. If the compressive strength can be predicted during the early curing stages, time and money can be saved and the quality of the final waste form guaranteed. It was determined that the 7- and 28-day compressive strength from radwaste cementation can be predicted during the mixing and early curing stages by at least three methods. The three that were studied were maturity, rheology, and impedance. Maturity is a temperature-to-time measurement, rheology is a shear stress-to-shear rate measurement, and impedance is the opposition offered to the flow of alternating current. These three methods were employed on five different cemented radwaste concentrations with three different water-to-cement ratios; thus, a total of 15 different mix designs were considered. The results showed that the impedance was the easiest to employ for an on-line process. The results of the impedance method showed a very good relationship between impedance and water-to-cement ratio; therefore, an accurate prediction of compressive strength of cemented radwaste can be drawn from this method. The results of the theology method were very good. The method showed that concrete conforms to the Bingham plastic rheologic model, and the theology method can be used to predict the compressive strength of cemented radwaste, but may be too cumbersome. The results of the maturity method were shown to be limited in accuracy for determining compressive strength.

  8. Quality control of cast brake discs

    Directory of Open Access Journals (Sweden)

    M. Stawarz

    2008-04-01

    Full Text Available The largest industrial application so far have the gray cast irons which are characterized by low tensile and bending strength, while at the same time they have good ultimate comprehensive strength. Additionally, the fatigue strength of gray cast irons is comparatively low and they are only to some extend sensitive for the surface waters effects. Cast iron is the material, which is comparatively easy to be processed, and for this reason – it is not expensive. Brake discs are exploited in particularly hard conditions. They must be resistant both against the thermal fatigue and abrasion wearing (at dry friction as well as against seizing, corrosion and mechanical load [1-3]. The gray cast iron, better than other materials, fulfills all the requirements necessary for making the material for the casts resistant against such tough conditions. This work reflects the researches aiming to define the quality of cast brake discs (ventilated and non-ventilated ones upon a period of their exploitation in real conditions. The following researches were performed: evaluations of the disc surface condition, measurement of disc thickness, examination of run – out flank and metallographic analysis. In order to more detailed recognition of mechanisms and reasons of brake discs wearing in real conditions, one should conduct additional examinations: computer analysis of the microstructure, chemical composition analysis, etc., as well as study of the technology of their production in foundries, where they are manufactured [4]. By obtaining the full set of the mentioned above data one can draw final conclusions and remove causes of possible defects.

  9. 21 CFR 111.105 - What must quality control personnel do?

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What must quality control personnel do? 111.105... for Quality Control § 111.105 What must quality control personnel do? Quality control personnel must... manufacturing record. To do so, quality control personnel must perform operations that include: (a) Approving...

  10. Advanced methods of quality control in nuclear fuel fabrication

    International Nuclear Information System (INIS)

    Under pressure of current economic and electricity market situation utilities implement more demanding fuel utilization schemes including higher burn ups and thermal rates, longer fuel cycles and usage of Mo fuel. Therefore, fuel vendors have recently initiated new R and D programmes aimed at improving fuel quality, design and materials to produce robust and reliable fuel. In the beginning of commercial fuel fabrication, emphasis was given to advancements in Quality Control/Quality Assurance related mainly to product itself. During recent years, emphasis was transferred to improvements in process control and to implementation of overall Total Quality Management (TQM) programmes. In the area of fuel quality control, statistical control methods are now widely implemented replacing 100% inspection. This evolution, some practical examples and IAEA activities are described in the paper. The paper presents major findings of the latest IAEA Technical Meetings (TMs) and training courses in the area with emphasis on information received at the TM and training course held in 1999 and other latest publications to provide an overview of new developments in process/quality control, their implementation and results obtained including new approaches to QC

  11. Radiologically Guided Bone Biopsy: Results of 502 Biopsies

    International Nuclear Information System (INIS)

    Purpose: To analyze the results of 502 biopsies over a 19-year period for the purpose of highlighting the results that can be expected from such a large study, with emphasis on needle choice and anesthetic methods. Methods: The histological, cytological, and microbiological results of 477 patients who had 502 bone biopsies carried out between July 1977 and March 1996 were studied. Less than 5% of patients required second biopsies. There were almost equal numbers of males and females in the group. The lesions were visible radiologically and most of the biopsies were carried out by a single operator. The lesions were classified on their histopathological, cytopathological, and microbiological findings. Results: Tumors accounted for 40% of the biopsies, and infection for 16%. Biopsies which did not yield a 'positive' diagnosis accounted for 31%; these included specimens reported as normal, or as showing reactive changes, repair, remodelling, non-specific features, inflammation (but not clearly infective), or no evidence of malignancy or inflammation. Less than 4% of biopsies were incorrect, and some of these were re-biopsied. Conclusion: Bone biopsy is a valuable technique for positive diagnosis of malignancy or infection, as it enables a definitive plan for treatment and management of patients to be established. Exclusion of serious pathology is almost equally important. In principle, any osseous site can be biopsied using fluoroscopic or computed tomographic guidance. Care in the biopsy technique and selection of the bone needle is required

  12. Image-Guided percutaneous biopsies with a biopsy gun

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Kyung Hwan; Lim, Hyo Keun; Kim, Eun Ah; Yun, Ku Sub; Bae, Sang Hoo; Shin, Hyung Sik [Hallym University College of Medicine, Seoul (Korea, Republic of)

    1994-07-15

    We report the results of image-guided percutaneous biopsies with a biopsy gun and evaluate the clinical usefulness. One hundred and five biopsies under ultrasonographic or fluoroscopic guidance were performed. Various anatomic sites were targeted(liver; 50, chest; 22, kidney; 12, pancreas; 8, intraperitoeum; 7, retroperitoneum; ). Obtained tissue was diagnostic in 98 of the 105 biopsies(93%). In each instance, representative core tissue specimens were obtained. Evaluation of the core tissue by pathologist revealed consistent, uniform specimens that contained significant crush artifact in no case. Five biopsies yielded inadequate tissue which were too small for histopathologic interpretation or were composed of necrotic debris. Two biopsies yielded adequate tissues, but tissues were not of the target. The diagnoses were malignancy in 77 biopsies and benign disease in 21 biopsies. No complications other than mild, localized discomfort were encountered except a transient hemoptysis and pneumothorax which was observed in two patients. Cutting biopsy with a biopsy gun provided sufficient amount of target tissue for an accurate diagnosis of malignant and benign disease. It was a safe and useful procedure for percutaneous biopsy.

  13. Statistical Process Control: Going to the Limit for Quality.

    Science.gov (United States)

    Training, 1987

    1987-01-01

    Defines the concept of statistical process control, a quality control method used especially in manufacturing. Generally, concept users set specific standard levels that must be met. Makes the point that although employees work directly with the method, management is responsible for its success within the plant. (CH)

  14. Design and implementation of the STKOS quality-control system

    Institute of Scientific and Technical Information of China (English)

    Haixia; SUN; Danya; LI; Junlian; LI; Sizhu; WU; Tiejun; HU; Qing; QIAN

    2015-01-01

    Purpose: The aim of this study is to develop and implement a quality-control system to ensure authority control of the different knowledge units for the Scientific & Technological Knowledge Organization Systems(STKOS).Design/methodology/approach: First, we analyzed quality-control requirements based on the construction of the STKOS Metathesaurus. Then we designed a quality-control framework, the task management and transfer mechanism, and a service model. Afterwards, we carried out the experiments to check the rules and algorithms used in the system. Finally, the system was developed, and gradually optimized during its service.Findings: The quality-control system supports collaborative knowledge construction, as well as consistency checks of knowledge units with different granularity levels, including terminologies, relationships, and concepts. The system can be flexibly configured.Research limitations: The system is oriented to an English-language knowledge organization system, and may not perform well with Chinese-language systems and ontologies.Practical implications: The system can be used to support the construction of a single knowledge organization system, as well as data warehousing and interoperable knowledge organization systems. Originality/value: The STKOS quality-control system not only focuses on content building for the knowledge system, but also supports collaborative task management.

  15. Analysis of Information Quality in event triggered Smart Grid Control

    DEFF Research Database (Denmark)

    Kristensen, Thomas le Fevre; Olsen, Rasmus Løvenstein; Rasmussen, Jakob Gulddahl

    2015-01-01

    dependability of existing networks. We develop models for network delays and information dynamics, and uses these to model information quality for three given information access schemes in an event triggered control scenario. We analyse the impact of model parameters, and show how optimal choice of information...... access scheme depends on network conditions as well as trade-offs between information quality, network resources and control reactivity.......The integration of renewable energy sources into the power grid requires added control intelligence which imposes new communication requirements onto the future power grid. Since large scale implementation of new communication infrastructure is infeasible, we consider methods of increasing...

  16. Quality control of rain data used for urban runoff systems

    DEFF Research Database (Denmark)

    Jørgensen, H. K.; Rosenørn, S.; Madsen, Henrik;

    1998-01-01

    When improving software packages such as MOUSE and SAMBA for designing sewers and storage basins, and simulating overflows and flooding the quality of the input becomes important. The essential input to these modelling tools are the historical rain series. This paper presents the procedures for...... collection and quality control of rain data from a network of tipping bucket rain gauges in Denmark carried out by the Danish Meteorological Institute. During rain, the RIMCO gauge counts the number of tips teach of 0.2 mm of precipitation) every minute, The quality control of the rain data includes an...... automatic and a manual bit marking, where the automatic control basically is pointing out minutes with extreme intensities. In the manual control, the maximum intensities as well as the daily totals of precipitation are inspected, using weather charts, intensity plots and precipitation sums of nearby...

  17. Quality control of systems of portal imaging; Control de calidad de sistemas de imagen portal

    Energy Technology Data Exchange (ETDEWEB)

    Olasolo Alonso, J.; Martin Albina, M. L.; Otal Palacin, A.; Fuentemilla Urio, N.; Miquelez Alonso, S.; Pellejero Pellejero, S.; Maneru Camara, F.; Lozares Cordero, S.; Rubio Arroniz, A.

    2013-07-01

    The importance of accuracy and reproducibility of the positioning of the patient for the radiotherapy treatment, makes key the image quality of the image device portal used for the verification of such positioning. the objective of this work is the implementation of a procedure of quality control that easily and quickly verify the main parameters of image quality of the EPID. (Author)

  18. Quality control in a SSDL/NCL

    International Nuclear Information System (INIS)

    The rapid development in nuclear science and technology in particular in radiotherapy and industrial applications of ionizing radiation demands everywhere standardization and permanent control dosimetry. A national calibration laboratory for ionizing radiation must be designated as such by the appropriate authorities. The responsible government authorities should apply the Agency's Radiation Protection Standards and Measures and/or the national ones (when adequate) for the safe use of all kind of ionizing radiation. They should issue to the calibration laboratory a corresponding working licence when the irradiation facilities of the calibration laboratory become operational. The basic aim of a national calibration laboratory is to improve accuracy in radiation dosimetry and should therefore maintain and apply dosimetric equipment of the present state of art, i.e. secondary standards, for calibration of radiation measuring instrumentation for the whole country. It should also undertake measurements and calibrations of the output of radiation sources and installations in the field, whenever this will be required. In addition the calibration laboratory should be the preferred place for receiving training in applied radiation dosimetry. It should give advice to users on up-to-date measurement procedures and techniques. It should promote everywhere the safe application of ionizing radiation by supporting users of ionizing radiation for creation and distribution of better knowledge in the field of applied radiation dosimetry. The strict application of Radiation Protection Standards and Measures will ensure the protection of health and safety of both, the radiation workers and the individuals of the general public, without imposing undue burdens upon the use of ionizing radiation

  19. Different Methods for Prostate Biopsy and Biopsy Protocols

    Directory of Open Access Journals (Sweden)

    Mahyar Ghafoori

    2011-05-01

    Full Text Available Prostate carcinoma is one of the most common"nmalignancies among men. Increasing mortality rates due"nto prostate carcinoma have been observed worldwide."nThis disease usually progresses imperceptibly, for this"nreason; screening programs aimed at early detection"nhave been developed. The prostate specific antigen"n(PSA test is among the best screening tools available"nin medicine today because it is recognized as the best"nmarker for its early detection."nIn case of abnormal rise in PSA, the patient usually"nrefers for prostate biopsy under the guide of trans"nrectal ultrasonography (TRUS. Different methods are"nrecognized for prostate biopsy that may be divided"ninto two main categories namely, systematic biopsy"nand targeted biopsy."nIn systematic biopsy we divide the prostate gland"nrandomly to different sections and obtain biopsy"nspecimens from each section.The protocol of systematic biopsy is different among"ndifferent institutions. The number of biopsy specimens"ncould be started from less than 6 to more than 20"nbiopsies in some institutions. Increasing the number"nof biopsy specimens increases the detection rate for"nprostate cancer increasing the complications such"nas post biopsy prostatitis and septicemia, which are"nthe most important, as well. In scheduling a biopsy"nprotocol with high number of biopsies it is preferred"nto hospitalize the patient and prescribe intravenous"nantibiotics."nTargeted biopsy of the prostate means obtaining biopsy"nspecimens from a pathologic lesion that is suspicious"nfor prostate cancer. Different modalities could be"nused for detecting prostate cancer within the prostate"ngland. Transrectal ultrasonography, ultrasonography"nwith the use of ultrasound contrast agents, MRI of the"nprostate with the use of endorectal coil, dynamic MR"nstudy with contrast agent, diffusion weighted imaging"nof the prostate and MR spectroscopy all could help"nin the detection of a suspicious tumoral mass in the

  20. The accuracy of colposcopic biopsy

    DEFF Research Database (Denmark)

    Stoler, Mark H; Vichnin, Michelle D; Ferenczy, Alex;

    2011-01-01

    We evaluated the overall agreement between colposcopically directed biopsies and the definitive excisional specimens within the context of three clinical trials. A total of 737 women aged 16-45 who had a cervical biopsy taken within 6 months before their definitive therapy were included. Per......-protocol, colposcopists were to also obtain a representative cervical biopsy immediately before definitive therapy. Using adjudicated histological diagnoses, the initial biopsies and the same day biopsies were correlated with the surgically excised specimens. The overall agreement between the biopsies taken within 6...... degree of variance in the correlation, the overall agreement was 92% for CIN2-3/AIS. The overall agreement between the same day biopsy and definitive therapy specimen was 56% (weighted kappa = 0.41) (95% CI: 0.36-0.47), and the underestimation of CIN2-3/AIS was 57%. There were significant associations in...

  1. Model based control charts in stage 1 quality control

    OpenAIRE

    Koning, Alex

    1999-01-01

    textabstractIn this paper a general method of constructing control charts for preliminary analysis of individual observations is presented, which is based on recursive score residuals. A simulation study shows that certain implementations of these charts are highly effective in detecting assignable causes.

  2. Indoor air quality control techniques. Radon, formaldehyde, combustion products

    International Nuclear Information System (INIS)

    This book reviews and evaluates existing indoor air quality control techniques. The indoor air pollutants of most concern are radon, formaldehyde, and certain combustion products-nitrogen dioxide, carbon monoxide, carbon dioxide, and various respirable particles. Many techniques exist to control the concentration of these pollutants and other indoor pollutants that are only now being recognized as significant. The purpose of the book is to provide a current review and evaluation of these control techniques

  3. Analytical techniques and quality control in biomedical trace element research

    DEFF Research Database (Denmark)

    Heydorn, K.

    1994-01-01

    The small number of analytical results in trace element research calls for special methods of quality control. It is shown that when the analytical methods are in statistical control, only small numbers of duplicate or replicate results are needed to ascertain the absence of systematic errors....../kg. Measurement compatibility is obtained by control of traceability to certified reference materials, (C) 1994 Wiley-Liss, Inc....

  4. Usefulness of automated biopsy guns in image-guided biopsy

    International Nuclear Information System (INIS)

    To evaluate the usefulness of automated biopsy guns in image-guided biopsy of lung, liver, pancreas and other organs. Using automated biopsy devices, 160 biopsies of variable anatomic sites were performed: Biopsies were performed under ultrasonographic(US) guidance in 95 and computed tomographic (CT) guidance in 65. We retrospectively analyzed histologic results and complications. Specimens were adequate for histopathologic diagnosis in 143 of the 160 patients(89.4%)-Diagnostic tissue was obtained in 130 (81.3%), suggestive tissue obtained in 13(8.1%), and non-diagnostic tissue was obtained in 14(8.7%). Inadequate tissue was obtained in only 3(1.9%). There was no statistically significant difference between US-guided and CT-guided percutaneous biopsy. There was no occurrence of significant complication. We have experienced mild complications in only 5 patients-2 hematuria and 2 hematochezia in transrectal prostatic biopsy, and 1 minimal pneumothorax in CT-guided percutaneous lung biopsy. All of them were resolved spontaneously. The image-guided biopsy using the automated biopsy gun was a simple, safe and accurate method of obtaining adequate specimen for the histopathologic diagnosis

  5. 75 FR 80066 - Quality Control Requirements for Direct Endorsement Lenders; Notice of Proposed Information...

    Science.gov (United States)

    2010-12-21

    ... URBAN DEVELOPMENT Quality Control Requirements for Direct Endorsement Lenders; Notice of Proposed.... This Notice also lists the following information: Title of Proposal: Quality Control Requirements for... lenders, since these institutions must also conduct quality control on all loans they originate...

  6. 78 FR 69103 - 30-Day Notice of Proposed Information Collection: Quality Control for Rental Assistance Subsidy...

    Science.gov (United States)

    2013-11-18

    ... URBAN DEVELOPMENT 30-Day Notice of Proposed Information Collection: Quality Control for Rental... Information Collection: Quality Control for Rental Assistance Subsidy Determinations. OMB Approval Number... Quality Control process involves selecting a nationally representative sample of assisted households...

  7. Telepathology and Optical Biopsy

    Directory of Open Access Journals (Sweden)

    Olga Ferrer-Roca

    2009-01-01

    Full Text Available The ability to obtain information about the structure of tissue without taking a sample for pathology has opened the way for new diagnostic techniques. The present paper reviews all currently available techniques capable of producing an optical biopsy, with or without morphological images. Most of these techniques are carried out by physicians who are not specialized in pathology and therefore not trained to interpret the results as a pathologist would. In these cases, the use of telepathology or distant consultation techniques is essential.

  8. Secondary Control for Voltage Quality Enhancement in Microgrids

    DEFF Research Database (Denmark)

    Savaghebi, Mehdi; Jalilian, Alireza; Vasquez, Juan Carlos;

    2012-01-01

    In this paper, a hierarchical control scheme is proposed for enhancement of sensitive load bus (SLB) voltage quality in microgrids. The control structure consists of primary and secondary levels. The primary control level comprises distributed generators (DGs) local controllers. Each of these...... controllers includes a selective virtual impedance loop which is considered to improve sharing of fundamental and harmonic components of load current among the DG units. The sharing improvement is provided at the expense of increasing voltage unbalance and harmonic distortion. Thus, the secondary control...... level is applied to manage the compensation of SLB voltage unbalance and harmonics by sending proper control signals to the primary level. DGs compensation efforts are controlled locally at the primary level. The system design procedure for selecting proper control parameters is discussed. Simulation...

  9. Certification, accreditation, and quality control in behavior analysis

    OpenAIRE

    Moore, J.; Shook, G L

    2001-01-01

    Implementing quality control measures in the discipline and professional practice of behavior analysis is a challenging, but nevertheless important, step in the evolution of our field. The Association for Behavior Analysis currently seeks to ensure quality in behavior analysis by sponsoring an accreditation program for graduate academic programs and by promoting certification of individual practitioners. The accreditation reviews are conducted by ABA, whereas certification status is awarded b...

  10. Quality control for diagnostic oral microbiology laboratories in European countries

    OpenAIRE

    Rautemaa-Richardson, Riina; Wil A van der Reijden; Dahlen, Gunnar; Andrew J. Smith

    2011-01-01

    Participation in diagnostic microbiology internal and external quality control (QC) processes is good laboratory practice and an essential component of a quality management system. However, no QC scheme for diagnostic oral microbiology existed until 2009 when the Clinical Oral Microbiology (COMB) Network was created. At the European Oral Microbiology Workshop in 2008, 12 laboratories processing clinical oral microbiological samples were identified. All these were recruited to participate into...

  11. Quality control of radioactive waste disposal container for borehole project

    International Nuclear Information System (INIS)

    This paper explained quality control of radioactive disposal container for the borehole project. Non-destructive Testing (NDT) is one of the quality tool used for evaluating the product. The disposal container is made of 316L stainless steel. The suitable NDT method for this object is radiography, ultrasonic, penetrant and eddy current testing. This container will be filled with radioactive capsules and cement mortar is grouted to fill the gap. The results of NDT measurements are explained and discussed. (author)

  12. Quality Assurance and Control in Laboratory using Neutron Activation Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Y. S.; Moon, J. H.; Sun, G. M.; Kim, S. H.; Baek, S. Y.; Lim, J. M.; Kim, H. R

    2007-01-15

    In accordance with the increment of international trade associated with the worldwide globalization, the importance of quality assurance and control for the commodity produced from one's own country has been stressed. ISO (International Organization for Standards) defines quality control as 'the operational techniques and activities that are used to fulfill the requirements for quality'. Since 1996, the HANARO research reactor in the Korea Atomic Energy Research Institute has been operated thereafter initial critical operation on April 1995. Neutron activation analysis system and applied techniques which is one of a nuclear analytical technologies using reactor neutrons has been developed for user's supporting and the establishment of the quality system for a measurement and analysis, testing and inspection was implemented successfully. On the basis of the qualified NAA system, the test and measurement of more than 1500 samples which is requested from 30 organizations including industrial companies, universities and institutes carried out in NAA laboratory annually. Moreover, as the goal of mutual recognition agreement (MRA) which can be removed a technical barrier in international trade, the objectivity and the confidence of analytical quality in NAA laboratory became established through the installation of international accreditation system by implementing analytical quality system in accordance with international standards in 2001. The aim of the report was to summarize the technical management of introduction, methods and the results for a quality control and assurance which should be performed in NAA technique using the HANARO research reactor. The report will help building up effective quality control strategy in the future.

  13. Theoretical White Dwarf Spectra via the Internet: Quality Control

    Science.gov (United States)

    Ringat, E.; Reindl, N.

    2013-01-01

    The first decade of the Virtual Observatory (VO) built up services and tools for data conservation, handling, processing, analysis, etc. A new challenge in the immensely growing VO in operation is continuous quality control at different authority levels. Here we shed light on various aspects of theoretical white dwarf spectra that are provided via the registered TheoSSA VO service. We present benchmark tests that enable the VO user to judge their quality.

  14. The Emprovement of Percutaneous Puncture Core Renal Biopsy in Diffuse Diseases

    Directory of Open Access Journals (Sweden)

    Vdovin А.К.

    2013-09-01

    Full Text Available We developed methods to improve ultrasound-guided percutaneous renal puncture core biopsy in diffuse diseases. The use of semi-automatic needles True-Cut, caliber 14G, with harpoon-type mandrin, which enables to obtain high-quality tissue samples, up to 2 cm in length and up to 1.2 mm in thickness that makes it possible to perform a single tissue retrieval (2–3 — in exceptional cases. 40 patients underwent “free hand” biopsy using semi-automatic needles. The peculiarity of the suggested technique of biopsy needle visualization improvement is in the creation of induced anechoic space in paranephral cellular tissue by means of tissue infiltration by 0.25% novocaine solution. It helps to localize the tip of a mandrin immediately close to the renal surface and enables its controlled introduction into the selected biopsy area. To avoid the calices-pelvis system or vessel damage, the approach is along the line going obliquely superiorly down through parenchyma of the middle third of the kidney towards the lower pole at sufficient distance from the renal sinus echostructures. Informative material for histological study was obtained without complications in all cases. The optimized biopsy technique permits early activization of patients and their reduced (up to one day stay in hospital.

  15. Quality assurance/quality control, reliability and availability of nuclear power plants

    International Nuclear Information System (INIS)

    In a first part this lectures will present a survey on nuclear power production and plant performance in the Western World and discuss key parameters such as load factors and non-availability. Some main reasons for reliable performance of nuclear power plants are given. The second part of this lecture deals with the question how quality assurance and quality control measures do directly influence plant reliability, availability and, thus, economy. Derived from worldwide experience gained from operating nuclear power plants, it may be concluded that the implementation of an overall quality assurance programme does not only satisfy safety requirements set forth by the nuclear regulatory bodies, but has also a considerable impact on plant reliability and availability. A positive effect on these figures will be achieved if the established quality assurance programme provides for a coordinated approach to all activities affecting quality. It is discussed how the quality of a product should be controlled and what kind of quality assurance measures by performed examples are given to demonstrate that the expenditure for maintenance work on components will decrease if planned and systematic quality assurance actions have been implemented during all procurement stages. (orig./RW)

  16. Quality control for exposure assessment in epidemiological studies

    DEFF Research Database (Denmark)

    Bornkessel, C; Blettner, M; Breckenkamp, J;

    2010-01-01

    In the framework of an epidemiological study, dosemeters were used for the assessment of radio frequency electromagnetic field exposure. To check the correct dosemeter's performance in terms of consistency of recorded field values over the entire study period, a quality control strategy was...... developed. In this paper, the concept of quality control and its results is described. From the 20 dosemeters used, 19 were very stable and reproducible, with deviations of a maximum of +/-1 dB compared with their initial state. One device was found to be faulty and its measurement data had to be excluded...... from the analysis. As a result of continuous quality control procedures, the confidence in the measurements obtained during the field work was strengthened significantly....

  17. Low cost breast phantom prototype for quality control mammography

    International Nuclear Information System (INIS)

    A low cost breast phantom prototype for quality control in mammography was designed and built. The phantom was formed by acrylic and wax rectangular plates. Several pieces were inserted in order to simulated fibers, micro-calcifications and tumor masses, and to assessment the spatial and contrast resolutions. Different quality control imaging tests were carried out in 3 mammography equipment in clinical use comparing the home-made phantom with a commercial phantom. The results showed that our prototype can be used for mammography quality control according to the Brazilian guideline (regulation 453/98). The aim of this work is propose a low cost breast phantom for a future use in Brazilian hospitals. (author)

  18. CT dosimetry and quality control of its operation

    International Nuclear Information System (INIS)

    This thesis focuses on the dosimetry of a scanner, quality control of its operations and the development of a protocol. It allowed us the mastery of the art scanner and participation in all quality controls with appropriate ghosts. CT is a radiographic examination sophisticated and accurate, widely used to screen for various diseases, among other cancer. We worked on the dosimetry of a scanner and we have made simulations with a program called Impact that calculates the CT CTDI and the PDL and compared with values displayed on the console. Similarly, the software calculates the absorbed dose and compared with that calculated by Caldose X. This work is complemented by the development of a protocol with the quality control procedures of the image and dosimetry in chronological order.

  19. The Quality Control of the LHC Continuous Cryostat Interconnections

    CERN Document Server

    Bertinelli, F; Bozzini, D; Cruikshank, P; Fessia, P; Grimaud, A; Kotarba, A; Maan, W; Olek, S; Poncet, A; Russenschuck, Stephan; Savary, F; Sulek, Z; Tock, J P; Tommasini, D; Vaudaux, L; Williams, L

    2008-01-01

    The interconnections between the Large Hadron Collider (LHC) magnets have required some 40 000 TIG welded joints and 65 000 electrical splices. At the level of single joints and splices, non-destructive techniques find limited application: quality control is based on the qualification of the process and of operators, on the recording of production parameters and on production samples. Visual inspection and process audits were the main techniques used. At the level of an extended chain of joints and splices - from a 53.5 m half-cell to a complete 2.7 km arc sector - quality control is based on vacuum leak tests, electrical tests and RF microwave reflectometry that progressively validated the work performed. Subsequent pressure tests, cryogenic circuits flushing with high pressure helium and cool-downs revealed a few unseen or new defects. This paper presents an overview of the quality control techniques used, seeking lessons applicable to similar large, complex projects.

  20. Methods of Statistical Control for Groundwater Quality Indicators

    Science.gov (United States)

    Yankovich, E.; Nevidimova, O.; Yankovich, K.

    2016-06-01

    The article describes the results of conducted groundwater quality control. Controlled quality indicators included the following microelements - barium, manganese, iron, mercury, iodine, chromium, strontium, etc. Quality control charts - X-bar chart and R chart - were built. For the upper and the lower threshold limits, maximum permissible concentration of components in water and the lower limit of their biologically significant concentration, respectively, were selected. The charts analysis has shown that the levels of microelements content in water at the area of study are stable. Most elements in the underground water are contained in concentrations, significant for human organisms consuming the water. For example, such elements as Ba, Mn, Fe have concentrations that exceed maximum permissible levels for drinking water.

  1. Development and use of reference materials and quality control materials

    International Nuclear Information System (INIS)

    Current knowledge is summarized on correct use of commercially available certified reference materials (CRMs) and reference materials (RMs). Acknowledged are also the limitations and restrictions analysts have to face if they want to apply quality control. The concept of in-house RMs or quality control materials (QCMs) is advocated to supplement the use of CRMs for quality control purposes. On hand advice on how to select, prepare, characterize and use these QCMs is given from the experts' perspective. Several scenarios are described to make this concept widely applicable to: advanced laboratories with CRMs with validated analytical techniques available, laboratories with less experience and facilities, as well as cases were labile compounds and unstable matrices are involved. Each scenario considers different approaches to overcome the lack of appropriate CRMs and advise on the preparation of QCMs, which might fit the particular purpose

  2. Ultrasound-guided synovial biopsy: a safe, well-tolerated and reliable technique for obtaining high-quality synovial tissue from both large and small joints in early arthritis patients.

    OpenAIRE

    Kelly, S; Humby, F; Filer, A; Ng, N.; Di Cicco, M; Hands, RE; Rocher, V; Bombardieri, M; D'Agostino, MA; McInnes, IB; Buckley, CD; Taylor, PC; Pitzalis, C

    2013-01-01

    OBJECTIVE: To determine the tolerability, safety and yield of synovial tissue in an early arthritis cohort using a minimally invasive, ultrasound (US)-guided, synovial biopsy technique in small, medium and large joints. METHODS: 93 sequential biopsy procedures were assessed from a total of 57 patients (baseline and 36 repeat biopsies at 6 months) recruited as part of the 'Pathobiology of Early Arthritis Cohort' study. Patients completed a tolerability questionnaire prior to and following the ...

  3. Control of weld quality in large welded populations

    International Nuclear Information System (INIS)

    The use of factorial experimental design during weld procedure development, as a statistical tool for the control of weld quality in large welded populations, is investigated. As an example, it is applied to single pass welds made in the laboratory using the spacer to tube attachment geometry present in AGR boilers. The welds have been deposited using a robotic cold wire TIG technique. A replicated 25 factorial welding trial has been designed and evaluated experimentally. Transverse sections have been examined to determine weld penetration quality features. The means and variances of each quality feature have been calculated. Using a standard factorial analysis program the significant effects have been identified and incorporated into control equations. Using these data and having established minimum acceptance criteria. defect rates have been calculated as a function of weld position. The control equations have also been used to revise working point welding conditions, to achieve acceptable weld quality. These equations have also been used in conjunction with the reproducibility measurements to estimate the amount of weld quality variability that can be attributed to process control. (author)

  4. Results of a quality control on non-interventional studies

    Directory of Open Access Journals (Sweden)

    Hundt, Ferdinand

    2011-01-01

    Full Text Available Non-interventional studies (NIS have for decades been an established part of post-authorisation medicinal research. As early as the mid-nineties, there were at least rudimentary demands for controllable data quality. Beginning with the recommendations of the Federal Institute for Drugs and Medical Devices (BfArM on the execution of non interventional (observational studies of 1998 and finally with the guidelines and recommendations for ensuring Good Epidemiological Practice (GEP, with the VFA (Verband der forschenden Arzneimittelhersteller [German Association of Research-Based Pharmaceutical Companies] – Recommendations for the Improvement of Quality and Transparency of NIS and the joint recommendations of BfArM and PEI (Paul-Ehrlich-Institut on the execution of NIS, pharmaceutical companies are required to monitor and/or verify quality in the course of a project. According to a survey of pharmaceutical companies 2010, about one third of the companies surveyed to date carry out such quality controls on site, at participating study centres.This report deals with the results of such quality control measures in 4 completed projects. The control rates defined in the respective cohort study plans, the measures carried out on site and any consequent measures, such as adjustment of forms, reduction of consultation time and necessary organisational changes are described. A high level of agreement between the data collected and the original patient documents is found, comparable to that in clinical trials.

  5. Results of a quality control on non-interventional studies.

    Science.gov (United States)

    Wörz, Karl; Hundt, Ferdinand

    2011-01-01

    Non-interventional studies (NIS) have for decades been an established part of post-authorisation medicinal research. As early as the mid-nineties, there were at least rudimentary demands for controllable data quality. Beginning with the recommendations of the Federal Institute for Drugs and Medical Devices (BfArM) on the execution of non interventional (observational) studies of 1998 and finally with the guidelines and recommendations for ensuring Good Epidemiological Practice (GEP), with the VFA (Verband der forschenden Arzneimittelhersteller [German Association of Research-Based Pharmaceutical Companies]) - Recommendations for the Improvement of Quality and Transparency of NIS and the joint recommendations of BfArM and PEI (Paul-Ehrlich-Institut) on the execution of NIS, pharmaceutical companies are required to monitor and/or verify quality in the course of a project. According to a survey of pharmaceutical companies 2010, about one third of the companies surveyed to date carry out such quality controls on site, at participating study centres. This report deals with the results of such quality control measures in 4 completed projects. The control rates defined in the respective cohort study plans, the measures carried out on site and any consequent measures, such as adjustment of forms, reduction of consultation time and necessary organisational changes are described. A high level of agreement between the data collected and the original patient documents is found, comparable to that in clinical trials. PMID:21863135

  6. Quality

    International Nuclear Information System (INIS)

    What is quality? How do you achieve it? How do you keep it once you have got it. The answer for industry at large is the three-step hierarchy of quality control, quality assurance and Total quality Management. An overview is given of the history of quality movement, illustrated with examples from Schlumberger operations, as well as the oil industry's approach to quality. An introduction of the Schlumberger's quality-associated ClientLink program is presented. 15 figs., 4 ills., 16 refs

  7. Study of prostate biopsy robot system

    Institute of Scientific and Technical Information of China (English)

    ZHANG Yong-de; ZHANG Long; ZHAO Yan-jiang; ZHANG Yan-hua

    2009-01-01

    A system for prostate biopsy with robot assistance was proposed. The system consists of Motoman robot, needle insertion mechanism, and control software. A experiment was held with this software, and it proved that the whole system is simple, reliable and good application.

  8. Effects of percutaneous needle liver biopsy on dairy cow behaviour

    DEFF Research Database (Denmark)

    Mølgaard, Lene; Damgaard, Birthe Marie; Bjerre-Harpøth, Vibeke;

    2012-01-01

    In cattle, percutaneous needle liver biopsy is used for scientific examination of liver metabolism. The impact of the biopsy procedure is, however, poorly investigated. Our aim was to examine the behaviour of dairy cows during and after liver biopsy. Data were collected from 18 dry cows....... Percutaneous needle liver biopsies (after administration of local anaesthesia (2% Procaine)) and blood samples were taken during restraining. During the control treatment, animals were restrained and blood sampled. During the biopsy procedure, cows showed increased restlessness (P = 0.008), frequency of head...... behavioural changes for up to 19 h – and particularly for behaviour previously associated with pain. Even though the exact welfare impact of percutaneous needle liver biopsies in cows is not known, and the magnitude of the behavioural changes was limited, pain always has negative effects on animal welfare...

  9. Percutaneous transhepatic biliary biopsy using gastrofiberscopic biopsy forceps.

    OpenAIRE

    Kim, C. S.; Han, Y M; Song, H. Y.; Choi, K. C.; Kim, D. G.; B.H. Cho

    1992-01-01

    To obtain a histopathologic diagnosis at the site of a biliary obstruction, we recently have performed 24 cases of biliary biopsy using gastrofiberscopic biopsy forceps (Olympus, Tokyo, Japan) via transhepatic tracts provided in the course of the procedure of percutaneous biliary drainage. Histopathologic diagnosis was successfully made at the first attempt of biopsy procedure but a second trial was made a week later in 6 cases who were negative for malignant cells on the first attempt. The h...

  10. [Internal quality control for antimicrobial susceptibility test: an experience feedback].

    Science.gov (United States)

    Vedy, Serge

    2012-01-01

    Internal quality control (IQC) position in antimicrobial susceptibility testing must be evaluated attentively before using. Ours S. aureus ATCC 25923 use during year 2011 has given precious information that can be useful for other laboratories. First, IQC should never be used before checking that all the realisation process steps are controlled. It will then appear that reagents are the most susceptible to give false results. That's what happens in 2.74% of antimicrobial susceptibility test. IQC is then useful to limit their clinical's impact. However, IQC use also shows that quality improvement will be difficult without industrial producer's involvement. PMID:22826843

  11. Procedures for quality control in Doppler ultrasound equipment

    International Nuclear Information System (INIS)

    Different international recommendations suggest an application of quality control programs in ultrasound equipment. However, procedures and reference values for Doppler test are not yet well defined. This work aims to present quantitative and qualitative tests for evaluation of quality control at Doppler ultrasound equipment. The following tests were performed: Doppler Signal Sensitivity; Color Flow Sensitivity; Flow Sensitivity at Depth; Color Flow B-Mode Image Congruency; Directional Discrimination; Accuracy of Flow Velocity Readout and Accuracy of Sample Gate Positioning. The values found will be used as baseline for comparisons over time. (author)

  12. Review of 18F-FDG Synthesis and Quality Control

    OpenAIRE

    Yu, S.

    2006-01-01

    This review article covers a concise account on fludeoxyglucose (18F–FDG) synthesis and quality control procedures with emphasis on practical synthesis Currently, 18F–FDG is the most successful PET radiopharmaceutical so far. The advancement in synthesis and quality control of 18F–FDG, together with its approval by the US FDA and the availability of reimbursement, are probably the main reasons for the flourish of clinical PET over the last 20 years. 18F–FDG can be synthesised by either electr...

  13. Quality control and quality assurance procedures at the THOR BNCT facility

    International Nuclear Information System (INIS)

    Various quality control (QC) and quality assurance (QA) procedures of the boron neutron capture therapy (BNCT) beam at the Tsing Hua Open-pool Reactor (THOR) are established to ensure beam availability and quality. The QC/QA methods mainly employ foil activation and paired ionization chambers, respectively, for beam intensity check and dose assessment. Beam intensity is monitored on-line by using three dead-time corrected fission chambers. In addition to the periodic QC/QA activities regarding beam quality and the monitoring system, the quick QC/QA performed in an all-in-one phantom will be executed less than 70 min before the clinical treatment to guarantee beam quality. The QC/QA procedures have been gradually established and the actual performance satisfied the preset criteria defined for the BNCT facility at THOR.

  14. Analytical chemistry measurements quality control program using computer applications

    International Nuclear Information System (INIS)

    An Analytical Chemistry Measurements Quality Control Program assures the reliability of analytical measurements performed at the Barnwell Nuclear Fuel Plant. The program includes training, methods quality control, replicate samples and measurements, mass measurements, interlaboratory sample exchanges, and standards preparation. This program has been designed to meet the requirements of 10CFR70.57. Portions of the program have been automated by using a PDP 11/35 computer system to provide features which are not readily available in manual systems. These include such items as realtime measurement control, computer calculated bias and precision estimates, various surveillance applications, and evaluation of measurement system variables. The efficiency of the computer system has been demonstrated in gathering and assimilating the results of over 1100 quality control samples during a recent cold chemical checkout campaign. These data were used to determine equations for predicting measurements reliability estimates; to evaluate measurement performance of the analysts, equipment, and measurement period; and to provide directions for chemistry methods modifications and additional training requirements. A procedure of replicate sampling and measuring provides random error estimates. The analytical chemistry measurement quality control activities during the campaign represented about 10% of the total analytical chemistry effort

  15. 21 CFR 111.127 - What quality control operations are required for packaging and labeling operations?

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What quality control operations are required for... and Process Control System: Requirements for Quality Control § 111.127 What quality control operations are required for packaging and labeling operations? Quality control operations for packaging...

  16. 21 CFR 111.130 - What quality control operations are required for returned dietary supplements?

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What quality control operations are required for... and Process Control System: Requirements for Quality Control § 111.130 What quality control operations are required for returned dietary supplements? Quality control operations for returned...

  17. Quality Control of a detector probe for radio guided surgery; Control de calidad de una sonda detectora para cirugia radioguiada

    Energy Technology Data Exchange (ETDEWEB)

    Barreto, A. C.; Cardoso, G.; Ferreira, L. S.; Santos, A.

    2013-07-01

    Breast cancer is the most common tumor in women, with increasing incidence worldwide. The dissection axillary lymph node is a reason for increased morbidity of breast surgery and have been replaced by sentinel node biopsy. The quality and performance of the detector probe affect the success of sentinel node surgery. The main objective of this work is to develop a set of practical tests to evaluate the performance of a probe for detecting sentinel node. (Author)

  18. Integrated evolutionary computation neural network quality controller for automated systems

    Energy Technology Data Exchange (ETDEWEB)

    Patro, S.; Kolarik, W.J. [Texas Tech Univ., Lubbock, TX (United States). Dept. of Industrial Engineering

    1999-06-01

    With increasing competition in the global market, more and more stringent quality standards and specifications are being demands at lower costs. Manufacturing applications of computing power are becoming more common. The application of neural networks to identification and control of dynamic processes has been discussed. The limitations of using neural networks for control purposes has been pointed out and a different technique, evolutionary computation, has been discussed. The results of identifying and controlling an unstable, dynamic process using evolutionary computation methods has been presented. A framework for an integrated system, using both neural networks and evolutionary computation, has been proposed to identify the process and then control the product quality, in a dynamic, multivariable system, in real-time.

  19. standards used for quality control of nuclear fuels

    International Nuclear Information System (INIS)

    Nuclear fuels and fuel materials are subject to stringent restrictions as to their quality. The standards and regulations that apply vary according to reactor type and country and the standards are stated in the quality assurance documents. The concept of quality assurance has altered the conventional quality control tests and procedures, defining which control tests are to be applied and how. Although most of the tests and measurements allow the determination of tolerances to be decided according to the agreement between the buyer and the seller, exacting procedures apply to which instruments and equipment are used for these tests and measurements, how these instruments are standardized.Detailed explanations of test methods and their documentation is a requirement in all standards. The purpose of this work is to study which standards, tests and measurements apply to the nuclear fuel production. Only the standards that apply to various stages of the nuclear fuel production (powder preparation, pellet production, fuel element and fuel assembly fabrication) are reviewed. Process and documentation control, design and licensing requirements and the frequency of inspections are quality assurance subjects. Some ASTM standards are given as examples

  20. Study on quality standards of engineering control net

    International Nuclear Information System (INIS)

    Four quality standards of the control net for the map surveying, the control net for constructing and deformation monitoring net have been put forward in the light of the references of the classic free net distributed error and the order deficit one, i.e. precision standard, standards of the total precision and the local one, reliability standard, inner reliability and outer reliability as well as measurement, sensitivity standard and economic standard. (author)

  1. Quality control for the continuous casting process using electromagnetic transducers

    OpenAIRE

    I.S. Kim; Son, J.S.; Kim, H. J.; B.S. Sung

    2008-01-01

    Purpose: The continuous casting process is controlled automatically because various sensors and control unitsare connected to the mold and lower tundish roll. The solidification point in the process has a major factor onthe quality of products, but the point has been predicted depending on the inaccurate calculated results from acomputer simulation until now. Therefore, the objective of this paper is to develop the EMAT sensors for themeasurement of the solidification point made by a through ...

  2. Assuring Quality and Welfare at Control Posts: a European Perspective

    OpenAIRE

    Evangelia N. Sossidou; Kees de Roest

    2012-01-01

    In this paper various welfare aspects of long distance transport of animal are introduced. Scientific evidence ispresented together with ethical and public concerns, as well as enforcement problems with examples from currentpractice and research. The on-going project on ‘Renovation and promoting high quality control posts in the EuropeanUnion’ is presented as it foresees a significant improvement of the equipment as well as the management of 12Control Posts (CPs) located at the cross roads of...

  3. FRAUD, CORRUPTION IN THE PRIVATE SECTOR AND INTERNAL CONTROL QUALITY

    OpenAIRE

    IONESCU, Luminiţa

    2011-01-01

    The global economic crunch had a big impact on the private sector all over the world. Media and controllers presented cases of corruption in business and identified special areas where companies, governments, investors, consumers and stakeholders can contribute to stop fraud and corruption. Controllers and auditors are rebuilding public trust in the accounting profession, in order to provide high-quality training, regulation, specialist knowledge and professional advice.Fraud and corruption a...

  4. Analytical quality control in studies of environmental exposure to mercury

    International Nuclear Information System (INIS)

    The work of the laboratory for quality control in this co-ordinated project for the period from November 1993 to June 1994 is presented. The major effort was devoted to assisting in establishing the homogeneity and total methylmercury levels in two new hair reference materials prepared as control materials for the project, numbered 085 (spiked) and 086 (natural level). Results for some hair materials from participants are also given. (author)

  5. Quality control in screening programs for cervical cancer

    International Nuclear Information System (INIS)

    The malignancy of the cervix is one of the few locations avoidable cancers, if detected before it progresses to the infiltration. The most efficient way of early detection is through a screening program to provide women undertaking a regular and quality Pap smear. If this test results abnormal, the program offers easier access to specialized care, effective treatment, and follow-up. The objective of this article is to present usefulness of methods for quality control used in screening programs for cervical cancer to detect their inadequacies. Here are some factors and conditions that must be considered in each of the steps to take, for a cervical cancer screening program to be successful and to meet the objectives proposed in reducing mortality due to this cause. This document contains some useful indexes calculated to ensure quality throughout the process. There should be the measurement of quality throughout the screening process that allows collecting of reliable data as well as correcting deficiencies

  6. Universal Power Quality Controller Modeling and Inverters Loading Analysis

    Directory of Open Access Journals (Sweden)

    F. Gharedaghi

    2011-11-01

    Full Text Available As much as nonlinear loads and power electronics devices are more applied in power distribution systems, the importance of power quality increases. This study proposes a Universal Power Quality Conditioner (UPQC with double-converter structure. The operation principle, the algorithm of compensation reference generation, and the control method are introduced. Computer simulation and many prototype experiments are carried out to verify the operation principle and investigate the compensation characteristics of UPQC for different power quality problems. It is verified that the UPQC can effectively compensate multiple different power quality interferences originated either from the load side or from the line side. The capacity of series and shunt inverters is calculated through loading calculations of these inverters applying phasor diagram to increase the design accuracy. The results of simulation in MATLAB/SIMULINK software show that the system operates correctly.

  7. Cooling water conditioning and quality control for tokamaks

    International Nuclear Information System (INIS)

    Designers and operators of Tokamaks and all associated water cooled, peripheral equipment, are faced with the task of providing and maintaining closed-loop, low conductivity, low impurity, cooling water systems. Most of these systems must provide large volumes of high quality cooling water at reasonable cost and comply with local and state government orders and EPA mandated national pretreatment standards and regulations. This paper discusses the DIII-D water quality requirements, the means used to obtain the necessary quality and the instrumentation used for control and monitoring. Costs to mechanically and chemically condition and maintain water quality are discussed as well as the various aspects of complying with government standards and regulations

  8. Quality control and disinfestation of spices for export

    International Nuclear Information System (INIS)

    India is the largest producer, consumer and exporter of spices in the world. Other than a few, all spices are grown in this country. The production is estimated at 2.6 million tonnes with an export of about 0.22 million tonnes valued around US $ 333 million. India's share in the world trade is over 40 % in quantity and 20 % in value. Many spices produced in India face quality problems as in other countries. For identifying quality produce, grade specifications have been introduced for all the important spices. With the liberalization of government controls, compulsory pre-shipment inspection has been withdrawn unless insisted by the buyer abroad. To meet the sanitary and phytosanitary requirements, the Spices Board has taken up a massive programme for upgradation of quality of Indian spices. Logo mark and Spice House Certificates are awarded to those spice exporting units having necessary infrastructure for assuring quality. By now, 6 units have been accredited to ISO 9000. Though different chemical and non-chemical treatments are available for improving hygienic quality, irradiation appears to be a reliable method. However, its wide application in the spice industry depends upon the conviction of the consumers of its safety. Because of the comprehensive programmes taken up for quality improvement of spices, India is confident of exporting spices meeting quality specifications prescribed by the importing countries. (author)

  9. Quality control and quality assurance philosophy introduced in national personnel dosimetry service

    International Nuclear Information System (INIS)

    There in National Personnel Dosimetry Service (NPDS) the implementation of the control system to guarantee the credibility of the measured personal dose equivalents results was given on the basis of the international recommendations published by the European Commission and the IAEA and in particular of the decree of the SUJB No. 132/2008 Coll. The quality control and the quality assurance are carried out in all three personal dosimetry services introduced in NPDS: in the film badge, thermoluminescent (TL) and neutron dosimetry. (authors)

  10. Implementation of quality control program in radiodiagnostic services

    International Nuclear Information System (INIS)

    This monograph is the first version of the implementation of the quality control programme in radiology diagnostic services. Here all information related to diagnostic quality to better radiation protection to patients and personnel was collected. The programme was implemented on the X-ray equipment at three hospitals (named hospital A, hospital B and hospital C) and included the evaluation of technical parameters such as kilovolts, exposition time, filtration, fields. In addition, dark room, chassis and image intensifiers were also evaluated. The procedures to carry out the quality control and the manner in which the observations, conclusions and recommendations should be formulated are based on documents issued by the International Commission on Radiological Protection (I.C.R.P.), International Atomic Energy Agency (I.A.E.A.) and World Health Organization (W.H.O.)

  11. Evidence Base for Quality Control Activities in Cardiovascular Imaging.

    Science.gov (United States)

    Eskandari, Mehdi; Kramer, Christopher M; Hecht, Harvey S; Jaber, Wael A; Marwick, Thomas H

    2016-03-01

    Quality control is pervasive in most modern business, but, surprisingly, is in its infancy in medicine in general-and cardiovascular imaging in particular. The increasing awareness of the cost of cardiovascular imaging, matched by a desire to show benefits from imaging to patient outcome, suggests that this deficiency should be reassessed. Demonstration of improved quality has been proposed to require a focus on several domains: laboratory organization, patient selection, image acquisition, image interpretation, and results communication. Improvement in these steps will require adoption of a variety of interventions, including laboratory accreditation, appropriate use criteria, and continuous quality control and enhancements in reporting, but the evidence base for the benefit of interventions on these steps has been sparse. The purpose of this review is to evaluate the current status and future goals of developing the evidence base for these processes in cardiovascular imaging. PMID:26965731

  12. Quality control for retinal OCT in multiple sclerosis

    DEFF Research Database (Denmark)

    Schippling, S; Balk, Lj; Costello, F;

    2015-01-01

    provide guidance on the use of validated quality control (QC) criteria for the use of OCT in MS research and clinical trials. METHODS: A prospective multi-centre (n = 13) study. Peripapillary ring scan QC rating of an OCT training set (n = 50) was followed by a test set (n = 50). Inter-rater agreement was...

  13. Quality Control Charts in Large-Scale Assessment Programs

    Science.gov (United States)

    Schafer, William D.; Coverdale, Bradley J.; Luxenberg, Harlan; Jin, Ying

    2011-01-01

    There are relatively few examples of quantitative approaches to quality control in educational assessment and accountability contexts. Among the several techniques that are used in other fields, Shewart charts have been found in a few instances to be applicable in educational settings. This paper describes Shewart charts and gives examples of how…

  14. Statistical Data Mining for Efficient Quality Control in Manufacturing

    DEFF Research Database (Denmark)

    Khan, Abdul Rauf; Schiøler, Henrik; Knudsen, Torben Steen;

    2015-01-01

    process e.g sensor measurements, machine readings etc, and the major contributor of these big data sets are different quality control processes. In this article we will present methodology to extract valuable insight from manufacturing data. The proposed methodology is based on comparison of probabilities...

  15. Radiation Dosimetry for Quality Control of Food Preservation and Disinfestation

    DEFF Research Database (Denmark)

    McLaughlin, W.L.; Miller, Arne; Uribe, R.M.

    1983-01-01

    In the use of x and gamma rays and scanned electron beams to extend the shelf life of food by delay of sprouting and ripening, killing of microbes, and control of insect population, quality assurance is provided by standardized radiation dosimetry. By strategic placement of calibrated dosimeters...

  16. Quality Control in Primary Schools: Progress from 2001-2006

    Science.gov (United States)

    Hofman, Roelande H.; de Boom, Jan; Hofman, W. H. Adriaan

    2010-01-01

    This article presents findings of research into the quality control (QC) of schools from 2001-2006. In 2001 several targets for QC were set and the progress of 939 primary schools is presented. Furthermore, using cluster analysis, schools are classified into four QC-types that differ in their focus on school (self) evaluation and school…

  17. Self-paced training for quality control inspectors

    International Nuclear Information System (INIS)

    The authors discuss the need for quality control (QC) training in the nuclear industry and propose requirements for QC training. This paper presents an overview of a self-paced training program for QC, including the characteristics and structure of such a program

  18. Transcription-associated quality control of mRNP

    DEFF Research Database (Denmark)

    Schmid, Manfred; Jensen, Torben Heick

    2013-01-01

    Although a prime purpose of transcription is to produce RNA, a substantial amount of transcript is nevertheless turned over very early in its lifetime. During transcription RNAs are matured by nucleases from longer precursors and activities are also employed to exert quality control over the RNA ...

  19. Quality Control through Design and Process: Gambrel Roof Truss Challenge

    Science.gov (United States)

    Ward, Dell; Jones, James

    2011-01-01

    Customers determine whether a product fulfills their needs or satisfies them. "Quality control", then, is the process of finding out what the customer wants, along with designing, producing, delivering, and servicing the product--and ultimately satisfying the customer's expectations. For many years, people considered a product to be of good…

  20. Quality control procedure for dental x-ray film processing

    International Nuclear Information System (INIS)

    Methods of obtaining the optimum processing from dental films are discussed. A method of quality control of developing conditions for dental x-ray films has been developed. It is relatively easy to maintain and is sufficiently accurate for practical purposes

  1. Quality control of collimator a system of image portal

    International Nuclear Information System (INIS)

    This paper presents the method followed in our Center to perform the quality control of the collimator (MLC) after the calibrations of the technical service, as well as regular monitoring of the position of the MLC to detect possible deviations. (Author)

  2. Monitoring Leptospira Strain Collections: The Need for Quality Control

    NARCIS (Netherlands)

    G.M. Cerqueira; A.J.A. McBride; A. Queiroz; L.S. Pinto; E.E. Silva; R.A. Hartskeerl; M.G. Reis; A.I. Ko; O.A. Dellagostin

    2010-01-01

    The purpose of this study was to perform a 16S sequence-based quality control of two Leptospira strain collections. 16S rRNA gene sequencing was used to verify two Leptospira reference collections provided by the World Health Organization and maintained at a reference laboratory for leptospirosis in

  3. Quality control tests for the CMS Barrel RPCs

    International Nuclear Information System (INIS)

    An RPC based system will be employed for the CMS muon first level trigger. Severe quality controls and certification have been established all along the entire production chain. Procedures are briefly described and results for the acceptance percentage are given for the second part of the single gaps and double gaps production. Summary results are also reported for the full sets of tested chambers

  4. The application of XRF technique in cement quality control

    International Nuclear Information System (INIS)

    XRF (X Ray Florescence) is a rapid and accurate analysis method that used in many fields. The theory of XRF and its application in quality control of raw cement will be introduced in this paper, and according to the experience, and the problems that attention should be paid to in utilizing and developing will be discussed also. (authors)

  5. Quality control of leather by terahertz time-domain spectroscopy.

    Science.gov (United States)

    Hernandez-Serrano, A I; Corzo-Garcia, S C; Garcia-Sanchez, E; Alfaro, M; Castro-Camus, E

    2014-11-20

    We use terahertz time-domain spectroscopy, combined with effective-medium theory, to measure the moisture content and thickness of leather simultaneously. These results demonstrate that this method could become a standard quality control test for the industrial tanning process. PMID:25607861

  6. HACCP system for quality control of food irradiation

    International Nuclear Information System (INIS)

    This paper introduces the Hazard Analysis and Critical Control Point System (HACCP) and analyses all hazard factors which would possibly affect the product quality in processing of irradiation dehydrated vegetables. It suggests that the irradiation food factories in China should set up HACCP as soon as possible and discusses the ways to set up HACCP

  7. A uniform, quality controlled Surface Ocean CO2 Atlas (SOCAT

    Directory of Open Access Journals (Sweden)

    T. Takahashi

    2012-08-01

    Full Text Available A well documented, publicly available, global data set of surface ocean carbon dioxide (CO2 parameters has been called for by international groups for nearly two decades. The Surface Ocean CO2 Atlas (SOCAT project was initiated by the international marine carbon science community in 2007 with the aim of providing a comprehensive, publicly available, regularly updated, global data set of marine surface CO2, which had been subject to quality control (QC. Many additional CO2 data, not yet made public via the Carbon Dioxide Information Analysis Center (CDIAC, were retrieved from data originators, public websites and other data centres. All data were put in a uniform format following a strict protocol. Quality control was carried out according to clearly defined criteria. Regional specialists performed the quality control, using state-of-the-art web-based tools, specially developed for accomplishing this global team effort. SOCAT version 1.5 was made public in September 2011 and holds 6.3 million quality controlled surface CO2 data points from the global oceans and coastal seas, spanning four decades (1968–2007. Three types of data products are available: individual cruise files, a merged complete data set and gridded products. With the rapid expansion of marine CO2 data collection and the importance of quantifying net global oceanic CO2 uptake and its changes, sustained data synthesis and data access are priorities.

  8. A uniform, quality controlled Surface Ocean CO2 Atlas (SOCAT

    Directory of Open Access Journals (Sweden)

    B. Pfeil

    2013-04-01

    Full Text Available A well-documented, publicly available, global data set of surface ocean carbon dioxide (CO2 parameters has been called for by international groups for nearly two decades. The Surface Ocean CO2 Atlas (SOCAT project was initiated by the international marine carbon science community in 2007 with the aim of providing a comprehensive, publicly available, regularly updated, global data set of marine surface CO2, which had been subject to quality control (QC. Many additional CO2 data, not yet made public via the Carbon Dioxide Information Analysis Center (CDIAC, were retrieved from data originators, public websites and other data centres. All data were put in a uniform format following a strict protocol. Quality control was carried out according to clearly defined criteria. Regional specialists performed the quality control, using state-of-the-art web-based tools, specially developed for accomplishing this global team effort. SOCAT version 1.5 was made public in September 2011 and holds 6.3 million quality controlled surface CO2 data points from the global oceans and coastal seas, spanning four decades (1968–2007. Three types of data products are available: individual cruise files, a merged complete data set and gridded products. With the rapid expansion of marine CO2 data collection and the importance of quantifying net global oceanic CO2 uptake and its changes, sustained data synthesis and data access are priorities.

  9. Quality control: comparison of images quality with screen film system and digital mammography CR

    International Nuclear Information System (INIS)

    The mammography screen film system should be used as part of processing chemicals, revelation process, equipment and this system has have a progressive replacing by the digital technology Full Field Digital Mammography FFDM, Computed Radiography (CR) Mammography and hardcopy. This new acquisition process of medical images has improved radiology section; however it is necessary efficient means for evaluating of the quality parameters. It should be considered taking into account the adaptation of the existent equipment and that procedures adopted for the exam, as well the adaptation of the new mammography films, the radiologist view box constitutes a part of the quality control program. This program aims at obtaining radiography with good quality that allows obtaining more information for the diagnosis and decreases the patient dose. For evaluation the quality image, this article is focused on presenting the differences regarding the acquired images through simulator mammography radiographic PMMA (Poly methyl methacrylate) in CR Mammography system and screen film system. The tests were accomplished at the same equipment of Mammography with the Automatic Exposure Control using a tension of 28 kV for both systems. The quality tests evaluated the spatial resolution, the own structures of the phantom, artifacts, optical density and contrast with conventional and laser films by mammography system. The installation for the accomplishment of the test has a quality control program. The evaluation was based on the pattern developed by the competent organ of the State of Minas Gerais. In this study, it was verified that the suitable Phantom Mama used by the Brazilian School of Radiology for conventional mammography did not obtain satisfactory result for Spatial Resolution in the digital mammography system CR. The final aim of this work is to obtain parameters to characterize the reference phantom quality image in an objective way. These parameters will be used to compare

  10. Incorporating Quality Control Information in the Sensor Web

    Science.gov (United States)

    Devaraju, Anusuriya; Kunkel, Ralf; Bogena, Heye

    2013-04-01

    The rapid development of sensing technologies had led to the creation of large amounts of heterogeneous environmental observations. The Sensor Web provides a wider access to sensors and observations via common protocols and specifications. Observations typically go through several levels of quality control, and aggregation before they are made available to end-users. Raw data are usually inspected, and related quality flags are assigned. Data are gap-filled, and errors are removed. New data series may also be derived from one or more corrected data sets. Until now, it is unclear how these kinds of information can be captured in the Sensor Web Enablement (SWE) framework. Apart from the quality measures (e.g., accuracy, precision, tolerance, or confidence), the levels of observational series, the changes applied, and the methods involved must be specified. It is important that this kind of quality control information is well described and communicated to end-users to allow for a better usage and interpretation of data products. In this paper, we describe how quality control information can be incorporated into the SWE framework. Concerning this, first, we introduce the TERENO (TERrestrial ENvironmental Observatories), an initiative funded by the large research infrastructure program of the Helmholtz Association in Germany. The main goal of the initiative is to facilitate the study of long-term effects of climate and land use changes. The TERENO Online Data RepOsitORry (TEODOOR) is a software infrastructure that supports acquisition, provision, and management of observations within TERENO via SWE specifications and several other OGC web services. Next, we specify changes made to the existing observational data model to incorporate quality control information. Here, we describe the underlying TERENO data policy in terms of provision and maintenance issues. We present data levels, and their implementation within TEODOOR. The data levels are adapted from those used by

  11. Implementation to spanish protocol of quality control of accelerators to daily control of electron beams

    International Nuclear Information System (INIS)

    A revised procedure for daily control of the electron beams to make measurements more meaningful physically, having a better reproducibility and more in line with the recommendations of the Spanish Protocol for Quality Control in Electron Linear Accelerators Clinical Use. The daily quality control beams of high energy electrons that had been done so far was the finding that the record of a series of measures (symmetry, uniformity, stability, energy, beam central dose) were within tolerance values established. The amendment is to check the beam quality by directly measuring changes in absorption depth at which the dose is reduced to half its maximum value, R50.

  12. 40 CFR 81.88 - Billings Intrastate Air Quality Control Region.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Billings Intrastate Air Quality... Quality Control Regions § 81.88 Billings Intrastate Air Quality Control Region. The Metropolitan Billings Intrastate Air Quality Control Region (Montana) has been renamed the Billings Intrastate Air Quality...

  13. Quality assurance and quality control in Yugoslav environmental radiation protection metrological and legislation system

    International Nuclear Information System (INIS)

    Quality Assurance and Quality Control in Ionizing Radiation Metrology is performed through legal metrology, international and national intercomparation procedures and routine control of instrumentations and standards. Legal metrology defines methods, units, standards and instrumentations according to the technical and legal demands in all the aspects of Quality Assurance and Quality Control. According to international standards, legal metrology is performed by the national metrological organizations obliged to assure primary standards for physical quantities and their transfer to the user. In Yugoslavia the national metrological organization is the Federal Bureau for Measures and Precious Metals in charge to introduce primary and secondary standards and necessary legislations. International intercomparisons are within the domain of the Bureau International des Poids et Mesures, BIPM, in Sevre, France. Yugoslavia participated in international intercomparisons in December,1991 in Sevre and in Budapest, in 1995. In the last ten years, several national intercomparisons took place.Routine control of instrumentations and standards is regulated by the National Law On Units And Instrumentation ( Sl list SRJ, br.80/94, 28/96 i 12/98). Still, according to Organization International de Metrologie Legale OIML only a few of the 54 states-members (in 1996) developed the consistent legal system in the area of ionizing radiation concerning general public application, as it is the case for medical applications. Only 18 of them, mostly technically developed countries had legally regulated the control of instrumentations, units and quantities of ionizing radiation, including Yugoslavia

  14. Investigating Friendship Quality: An Exploration of Self-Control and Social Control Theories' Friendship Hypotheses

    Science.gov (United States)

    Boman, John H., IV; Krohn, Marvin D.; Gibson, Chris L.; Stogner, John M.

    2012-01-01

    While associations with deviant peers are well understood to impact individual development, less is understood about the relationship between friendship quality and delinquency. Two criminological theories--social control theory and self-control theory--are able to offer an explanation for the latter relationship. Social control and self-control…

  15. Physical aspects of quality assurance in radiotherapy: A protocol for quality control

    International Nuclear Information System (INIS)

    In consistency with the increasing requests from Member States for establishing radiotherapy programmes, an IAEA Technical Co-operation project was initiated in Latin America aimed at improving the physical aspects (as a complement to the clinical issues) of quality assurance in radiotherapy; this ARCAL XXX project (RLA/6/032) was classified as a Model Project of the IAEA. Among the important outcomes of the project were (i) the training of a considerable number of medical physicists in hospitals of the region, (ii) the development of a protocol for quality control procedures, and (iii) the organization of quality audit site visits (to the participant countries) where the implementation in hospitals of the developed quality control procedures is verified. The present publication is the protocol for quality control of the physical aspects of radiotherapy. It contains detailed procedures on what should be measured by a medical physicist in a radiotherapy treatment unit and related equipment, and how this should be made. The latter is made through several appendices, which make the document rather unique. The protocol was developed by medical physicists of the region for the professionals of the region, and it is the first document of this kind ever written in Spanish. A training course was organized in November 1998 (Havana, Cuba) where its practical implementation was taught. There are plans to have this document translated into different languages for the various regions having similar TC projects. (author)

  16. Quality control and quality standards for the production of bone allografts in China

    International Nuclear Information System (INIS)

    There is a rapid progress of tissue banking especially Bone Banking in China, In order to strengthen the control on medical devices, Ministry of Public Health (MPH) issued the 'Regulation on Supervision of Critical Medical Devices, MPH Decree No. 54' in 1997. The SPTB was requested to submit new application for the approval of production and providing of tissue allografts. The needed documents are clinical reports, package insert, quality standards of product, Quality System Regulation (QSR) and audit report. Quality System Regulation document adopted the GMP standard for medical devices of FDA, US (21 CFR 620-1997). SPTB will amend the existed Quality Manual to suit the requirement of QSR. Referring to the AATB Standards, SPTB established 'Technical Standards' for Tissue Banking and was approved by the local government, which will be the supplement of the submitted QSR document. Considering the need of market control, MPH requested to submit a 'Quality Standard of Product' and the method of inspection. SPTB has completed such standards for final inspection of bone products, which includes the test for residual water, microbiology, bone species, colour and structure. In addition, the Tissue Bank has completed standards for in process inspection, which includes residual blood, radiation sterilization, initial bioburden, package leakage and biomechanics. In-process inspection is important for the control of non-conforming final products to assure the safety and efficacy of bone grafts. Methods of in process inspection and final inspection are described and discussed in this paper

  17. 78 FR 55281 - 60-Day Notice of Proposed Information Collection: Quality Control for Rental Assistance Subsidy...

    Science.gov (United States)

    2013-09-10

    ... URBAN DEVELOPMENT 60-Day Notice of Proposed Information Collection: Quality Control for Rental... Collection Title of Proposal: Quality Control for Rental Assistance Subsidy Determinations. OMB Approval... million households covered by the Public Housing and Section 8 housing subsidies. The Quality...

  18. Quality control of radioimmunoassay kits of pituitary hormones

    International Nuclear Information System (INIS)

    The present work describe the quality control procedures carried out on three RIA-Kits by the Isotopes Centre of Cuba, The subject matter of study were ;: were: LH-RIA-Kit, FSH-RIA-Kit and Prolactin- RIA -Kit. The controls have included the characterization of the 125I labelled hormones the specific antibodies, the 2 nd antibodies, the standards curves and the control serum. For the validation of these Kits were used reference standards from the WHO (World Health Organizations) and Kits from CIS company (France) based on the IRMA assays technologies . The results obtained allow us encourage the reliability of RIA-Kits

  19. Region III involvement in quality control and quality assurance of radon testing methods

    International Nuclear Information System (INIS)

    Region III has set a goal of increasing the testing for radon by our residents. One approach to this goal, is to bolster the public's confidence in the testing laboratories. We believe that this can be done most effectively by assuring the quality of the measurements available to the public. All Proficient Laboratories and Pennsylvania Certified Laboratories have submitted a quality assurance (QA) program. A QA audit checklist has been developed which will be finalized and made available to the states in our Region. This paper deals with inspection, verification, and documentation of the various laboratories and their compliance with prudent measuring protocols and addresses the following items: Organization and responsibilities; Sampling procedures; Detector chain of custody; Measurement procedures, quality control checks; State certification and RMP; Data resection, validation, and reporting; Quality assurance reports to management; Interview and discussion of QA audit with responsible officer

  20. Quality assurance, fabrication, and accompanying quality control of CASTOR {sup registered} transport and storage casks

    Energy Technology Data Exchange (ETDEWEB)

    Beverungen, M.; Laug, R. [GNS Gesellschaft fuer Nuklear-Service mbH, Essen (Germany)

    2004-07-01

    In Germany, the Federal Institute for Materials Research and Testing (BAM, Berlin) acts as the competent authority for the approval of quality assurance measures of packages used in the transport of radioactive material. For this purpose, the German Federal Ministry of Transport issued the ''Technical Guideline on Measures for Quality Assurance (QM) and Quality Surveillance (QUe) for packages for transport of radioactive materials (TRV 006)''. Due to this guideline, every applicant for a cask license is requested to issue a written programme for design, fabrication, testing, documentation, operation, maintenance, and recurrent testing of packages. This programme has to be approved by BAM. Therefore, the company implemented and maintains a programme on basis of the TRV 006 and a Quality Management System on basis of the ISO 9001:2000 which cover all requirements of the guideline to ensure a controlled processes. The system is regularly assessed by BAM.

  1. Current status of quality evaluation of nursing care through director review and reflection from the Nursing Quality Control Centers

    OpenAIRE

    Duan, Xia; Shi, Yan

    2014-01-01

    Background: The quality evaluation of nursing care is a key link in medical quality management. It is important and worth studying for the nursing supervisors to know the disadvantages during the process of quality evaluation of nursing care and then to improve the whole nursing quality. This study was to provide director insight on the current status of quality evaluation of nursing care from Nursing Quality Control Centers (NQCCs). Material and Methods: This qualitative study used a sample ...

  2. Regional programme on quality control of radioimmunoassay: Development of human resources and external quality assessments

    International Nuclear Information System (INIS)

    Since 1978 the authors have been concerned with helping to standardize radioimmunoassay (RIA) methodology in Argentina and other Latin American countries by: (1) developing human resources through courses on quality control of RIA and training of fellows, and (2) developing four external quality assessment (EQA) schemes to evaluate the performance of laboratories in determining several analytes by RIA. The number of collaborating laboratories increased between the first and fourth schemes. The average analytical performance achieved by the participants in each scheme was estimated by the average between-laboratory variation. Thyroxine, cortisol and tri-iodothyronine were measured the most accurately. Different problems were evident in the RIAs of thyrotrophin, luteinizing hormone, follicle stimulating hormone, prolactin, testosterone, progesterone, cortisol, immunoglobulin E and human growth hormone. RIA of oestradiol showed the worst accuracy. Analysis of the results showed an increasing interest in RIA quality control as it was found to improve the reliability of RIA. (author)

  3. Genetic variation at loci controlling quality traits in spring wheat

    International Nuclear Information System (INIS)

    Selection for quality traits in bread wheat (Triticum aestivum L.) during early breeding generations requires quick analytical methods that need small grain samples. Marker assisted selection can be useful for the improvement of quality traits in wheat. The present study was conducted to screen 117 Pakistani adapted spring wheat varieties with DNA markers linked with genes controlling composition of low and high molecular weight glutenin subunits (LMW-GS and HMW-GS, respectively), starch viscosity, Polyphenol oxidase (PPO) activity and grain hardness. DNA fragments associated with the presence/absence of quality related genes were amplified using Polymerase chain reaction (PCR) and detected using agarose gel electrophoresis. Positive allele of beta-secalin, which indicates presence of 1B.1R translocation, was found in 77 (66%) varieties. The marker PPO05 was found in 30 (26%) varieties, indicating lower PPO activity. Grain hardness controlled by Pinb-D1b allele was present in 49 (42%) varieties. Allele Wx-B1b which confers superior noodle quality was found in 48 (41%) varieties. HMW-GS encoded by Glu-D1d allele that exerts a positive effect on dough strength was present in 115 (98%) varieties. LMW-GS alleles Glu-A3d and Glu-B3 were observed in 21 (18%) and 76 (65%) varieties, respectively. Results of the present study may help wheat breeders in selecting parents for improving desirable quality attributes of future wheat varieties. The varieties, identified having desirable quality genes, in this study can be used in the wheat breeding programs aiming to improve quality traits. Early generation marker assisted selection can help to efficiently utilize resources of a breeding program. (author)

  4. 21 CFR 111.135 - What quality control operations are required for product complaints?

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What quality control operations are required for... System: Requirements for Quality Control § 111.135 What quality control operations are required for product complaints? Quality control operations for product complaints must include reviewing and...

  5. Tc99m MDP kits, production and quality control

    International Nuclear Information System (INIS)

    MDP kits for labelling with Tc99m were locally produced in different conditions, and the conditions for preparation were optimized. The quality control studies showed that the prepared kits were very good quality and comparable with that imported. Radiochemical purities ranged between 95-98% while reduced technetium ranged between 2-3% and free pertechnetate did not exceed 1%. Bioscan and biodistribution studies also showed high localization of Tc99m in the skeleton of rats and rabbits. (author). 8 refs., 14 tabs

  6. [MRI-guided musculoskeletal biopsy].

    Science.gov (United States)

    Daecke, W; Libicher, M; Mädler, U; Rumpf, C; Bernd, L

    2003-02-01

    MRI-guided musculoskeletal biopsy has been mentioned to be a minimally invasive method to obtain specimens for diagnostic purposes in bone tumors. To evaluate the viability, to assess the accuracy, and to record possible complications of this method, clinical data of 19 MRI-guided biopsies were analyzed. Interventions were performed on 18 patients (1-78 years) as an outpatient procedure: 15 skeletal and 4 soft tissue biopsies were taken from the pelvis, upper limb,or lower limb. We used T1-weighted gradient echoes (GE) for locating the puncture site and T2-weighted turbo spin echoes (TSE) for visualization of needle position. In 14 of 18 MRI-guided biopsies, a definite histological diagnosis was obtained. According to the pathologist, the inadequate size of the specimen was the main reason for missing the diagnoses in four cases.Long intervention time and inappropriate biopsy tools proved to be the main disadvantages of MRI-guided biopsy, but technical improvement might solve these technical problems in future.A postbiopsy hematoma was the only complication observed. Once technically improved, MRI-guided biopsy could be a precise alternative routine method for musculoskeletal biopsies in future. PMID:12607083

  7. Biopsy of the Transplanted Kidney

    OpenAIRE

    Ahmad, Iftikhar

    2004-01-01

    This article describes the current state-of-the-art technique of percutaneous transplant renal biopsy. A brief overview of the history of transplant renal biopsy is given. The indications and contraindications are discussed, including pre- and postprocedure patient management. The technique of the procedure and the devices that are available in the market are described.

  8. Aspiration and Biopsy: Bone Marrow

    Science.gov (United States)

    ... The person performing the bone marrow aspiration and biopsy will know your medical history, but might ask additional questions, such as what medicines you're taking or whether you have any allergies. Be sure to ... on the aspiration and biopsy site about 30 minutes before the procedure. You ...

  9. Overall quality control in radiosurgery; Control de calidad global en radiocirugia

    Energy Technology Data Exchange (ETDEWEB)

    Banos Capilla, M. C.; Garcia Martinez, M. a.; Bea Gilbert, J.; Ros Garcia, L.; Gil Deltoro, P.

    2011-07-01

    Quality Control dosimetric and geometric is essential to ensure good treatment in stereotactic radiosurgery. Furthermore, the development of new diagnostic tools CT, MRI, fusion of both) and treatment (micromultilaminas, etc.) Allows increased accuracy thereof, and at the same time. requires a thorough quality control. Currently, the most complete and thorough is the use of dummies which are made multimodal image scans, where different plan dosimetry and radiate in the treatment unit with the relevant detector array.

  10. Renal biopsy: methods and interpretation.

    Science.gov (United States)

    Vaden, Shelly L

    2004-07-01

    Renal biopsy most often is indicated in the management of dogs and cats with glomerular disease or acute renal failure. Renal biopsy can readily be performed in dogs and cats via either percutaneous or surgical methods. Care should be taken to ensure that proper technique is used. When proper technique is employed and patient factors are properly addressed, renal biopsy is a relatively safe procedure that minimally affects renal function. Patients should be monitored during the post biopsy period for severe hemorrhage, the most common complication. Accurate diagnosis of glomerular disease, and therefore, accurate treatment planning,requires that the biopsy specimens not only be evaluated by light microscopy using special stains but by electron and immunofluorescent microscopy. PMID:15223207

  11. Genetic quality control in mass-reared melon flies

    International Nuclear Information System (INIS)

    Quality control in mass-reared melon flies, Bactrocera cucurbitae, after eradication is discussed, based on the results of artificial selection experiments. First, a brief history of quality control in mass-rearing of insects is described. In practical mass- rearing of melon fly, many traits have already been differentiated between mass-reared and wild flies. These differing traits are reviewed and the factors which caused these differences are considered. It was considered that the differences between wild and mass-reared melon flies depended on the selection pressures from the mass-rearing method. Next, the results of several artificial selection experiments using the melon fly are reviewed. Finally, consideration is given to some correlated responses to artificial selection in mass-rearing. Longevity that is correlated to early fecundity was successfully controlled by artificial selection for reproduction in the mass-rearing system. On the basis of these results, an improved method for quality control in mass-reared melon fly with considerations for quantitative genetics is discussed

  12. Double shell tanks (DST) chemistry control data quality objectives

    International Nuclear Information System (INIS)

    One of the main functions of the River Protection Project is to store the Hanford Site tank waste until the Waste Treatment Plant (WTP) is ready to receive and process the waste. Waste from the older single-shell tanks is being transferred to the newer double-shell tanks (DSTs). Therefore, the integrity of the DSTs must be maintained until the waste from all tanks has been retrieved and transferred to the WTP. To help maintain the integrity of the DSTs over the life of the project, specific chemistry limits have been established to control corrosion of the DSTs. These waste chemistry limits are presented in the Technical Safety Requirements (TSR) document HNF-SD-WM-TSR-006, Sec. 5 . IS, Rev 2B (CHG 200 I). In order to control the chemistry in the DSTs, the Chemistry Control Program will require analyses of the tank waste. This document describes the Data Quality Objective (DUO) process undertaken to ensure appropriate data will be collected to control the waste chemistry in the DSTs. The DQO process was implemented in accordance with Data Quality Objectives for Sampling and Analyses, HNF-IP-0842, Rev. Ib, Vol. IV, Section 4.16, (Banning 2001) and the U.S. Environmental Protection Agency EPA QA/G4, Guidance for the Data Quality Objectives Process (EPA 1994), with some modifications to accommodate project or tank specific requirements and constraints

  13. Control Quality of a Feedback Control System under Cyclostationary Noise in Power Line Communication

    Science.gov (United States)

    Carrizo, Cesar; Kobayashi, Kentaro; Okada, Hiraku; Katayama, Masaaki

    This paper discusses a control system that employs a power line to transfer signals to control the motion of a single machine, and explores the influence of packet losses on the quality of the control. As an example of a controlled system, a controller with a rotary inverted pendulum as a controlled object, is considered. The feedback loop in between is the power line. The control performance is evaluated in the power line cyclostationary noise environment and compared against the performance in a stationary noise environment. As a result, it is confirmed that the power line and its cyclostationary noise features present an advantage against transmission in a channel with stationary noise.

  14. Quality control of the software in the JT-60 computer control system

    International Nuclear Information System (INIS)

    Improvements of the JT-60 control system are constantly required as the experiments go on. In order to keep the integrity of the whole system in case of modifying the control functions, the idea of quality control has been introduced into the software development. The objective of quality control in the JT-60 control system is to accelerate the software development. The QC activities lay emphasis on making the present status of the software clear and establishing the standard procedure of the software development. The support tools for grasping the present status of the control system have been developed in the general purpose large computer, where the database on the structure of programs and the relations among programs and tables are installed. Document control is also very important. This paper reports these QC activities and their problems for the JT-60 control system. (author)

  15. Analysis of HPGe Spectrometer Stability - Internal Quality Control

    International Nuclear Information System (INIS)

    Laboratory for Nuclear and Plasma Physics, Institute ''Vinea'' is authorized and accredited in accordance with ISO/IEC 17025 for measurements of radionuclide content in environmental samples. In accordance with a standards request and international recommendations, TCS No. 24, Quality System Implementation for Nuclear Analytical Techniques, permanent internal quality control of semiconductor HPGe spectrometer has been conducted. Periodical testing of spectrometer characteristics and creation of control charts are included in internal quality control processes. The evaluation of the measuring system can be performed by periodical testing as follows: FWHM chart provides evaluation of the resolution of a detector. Variation of the FWHM could be caused by electronic noise inside the detector, or might indicate a vacuum problem; FWTM chart allows to monitor tailing due to damage of the detection crystal, bad P/Z ration may indicate a leakage current; The ratio FWHM/FWTM for different gamma ray energies allows to monitor the quality of the detector; Activity chart allows to monitor the stability of the whole method; Background chart might discover contamination; Peak position chart provide indications for electronic stability and the influence of environmental conditions such as temperature or humidity. Point sources 60Co and 137Cs were used as a control sources for FWHM, FWTM, FWHM/FWTM ratio and peak position testing. Presented control charts, for a period June - December 2010, were used for an analysis of spectrometer stability. These charts show that performances of analyzed HPGe spectrometer were stable, meaning that measurements results for environmental samples could be considered as reliable, i.e. that the practice of Laboratory fully consists with an international recommendations. (author)

  16. A Study on Power Quality Improvement in PWM Controlled AC Voltage Controller

    Directory of Open Access Journals (Sweden)

    Ahmet ALTINTAŞ

    2009-04-01

    Full Text Available A lot of topologies of pulse-width modulated (PWM-AC controllers for single-phase and three-phase systems are proposed up to date. PWM-AC controllers have important advantages compared with the phase-controlled AC controllers using thyristors and triacs. The PWM-AC controller has sinusoidal current waveforms, smaller THD values, better power factor, faster dynamics, and smaller input/output filter. This article presents a novel control technique for application to PWM-AC controllers with ability of generating fewer harmonics. In the proposed control method, both the traditional AC voltage controllers and the PWM-AC controllers are combined; and smaller THD values are obtained. Thus, the harmonic pollution in the power system will be reduced; and consequently, the power quality will be increased. For this purpose, computer simulations are performed in order to investigate the proposed controller performance. The obtained results are compared with the conventional PWM-AC controller.

  17. Quality control of the RMI's AWS wind observations

    Science.gov (United States)

    Bertrand, Cédric; González Sotelino, Luis; Journée, Michel

    2016-02-01

    Wind observations are important for a wide range of domains including among others meteorology, agriculture and extreme wind engineering. To ensure the provision of high quality surface wind data over Belgium, a new semi-automated data quality control (QC) has been developed and applied to wind observations from the automated weather stations operated by the Royal Meteorological Institute of Belgium. This new QC applies to 10 m 10 min averaged wind speed and direction, 10 m gust speed and direction, 2 m 10 min averaged wind speed and 30 m 10 min averaged wind speed records. After an existence test, automated procedures check the data for limits consistency, internal consistency, temporal consistency and spatial consistency. At the end of the automated QC, a decision algorithm attributes a flag to each particular data point. Each day, the QC staff analyzes the preceding day's observations in the light of the assigned quality flags.

  18. Minimalisasi Kekurangan Material Melalui Implementasi Quality Control Circle

    Directory of Open Access Journals (Sweden)

    Togar W. S. Panjaitan

    2011-01-01

    Full Text Available The revolution of traditional quality management concept into total quality management (TQM inspired industry for establishing and implementing quality control circle (QCC. Before starting a project as the implementation of the QCC, the training was held for supporting the knowledge of the QCC team. As the pilot project of the QCC, this research will try to minimize the percentage of the lack material in the production process of 8340 type by working together with the QCC team. The result of QCC implementation could reach the target set by the team, the percentage of the lack material reached less than 3%. The percentage of the lack material kontaktarm reduced from 3.09% to 0.00%, flachdrahtspule reduced from 9.20% to 0.40%, and niet reduced from 7.71% to 2.73%. Besides, the implementation of QCC also resulted in positive impact for all the members of the team about the benefits and experiences gained.

  19. Image quality evaluation and control of computer-generated holograms

    Science.gov (United States)

    Yoshikawa, Hiroshi; Yamaguchi, Takeshi; Uetake, Hiroki

    2016-03-01

    Image quality of the computer-generated holograms are usually evaluated subjectively. For example, the re- constructed image from the hologram is compared with other holograms, or evaluated by the double-stimulus impairment scale method to compare with the original image. This paper proposes an objective image quality evaluation of a computer-generated hologram by evaluating both diffraction efficiency and peak signal-to-noise ratio. Theory and numerical experimental results are shown on Fourier transform transmission hologram of both amplitude and phase modulation. Results without the optimized random phase show that the amplitude transmission hologram gives better peak signal-to noise ratio, but the phase transmission hologram provides about 10 times higher diffraction efficiency to the amplitude type. As an optimized phase hologram, Kinoform is evaluated. In addition, we investigate to control image quality by non-linear operation.

  20. Quality assurance and quality control program in individual monitoring service of the ENEA radiation protection institute

    International Nuclear Information System (INIS)

    Full text: The Individual Monitoring Service (IMS) of the ENEA Radiation Protection Institute, processes 80,000 dosemeters per year and is the only Italian Dosimetric Service supplying dosemeters for neutron radiation. It has been operating since the 1970s. The dosemeters have been designed, in house-developed and tested at ENEA Radiation Protection Institute throughout computational and experimental research. Since 2001 the ENEA IMS supplies personal dosemeters to assess Hp(d), which is required by Italian legislation (D.Lgs. 241/2000). In the 30 years of activity the ENEA-IMS has developed a learning of Quality Assurance (QA) and implemented Quality Control (QC) procedures to supply a reliable dosimetry service. In Italy, there are not yet requirements for approval of dosimetric service; however the application of a quality system to dosimetry is a quite established concept and few services have obtained certification in compliant with ISO 9000 standards, whereas accreditation in compliant with ISO 17025 is still on the way. In fact, although QA is sometimes a matter of common sense, the strategy for it towards the practical implementation of a QA program requires considerable thought. The IMS at ENEA has been always followed control procedures and internal tests to assure the quality of the whole system. Few examples will be given. The present paper describes the approach and actions which have been taken to 'translate' the actual 'ENEA Quality System' toward the accreditation according to ISO 17025. (author)