WorldWideScience

Sample records for biomedical test materials

  1. Superhydrophobic Materials for Biomedical Applications

    Science.gov (United States)

    Colson, Yolonda L.; Grinstaff, Mark W.

    2016-01-01

    Superhydrophobic surfaces are actively studied across a wide range of applications and industries, and are now finding increased use in the biomedical arena as substrates to control protein adsorption, cellular interaction, and bacterial growth, as well as platforms for drug delivery devices and for diagnostic tools. The commonality in the design of these materials is to create a stable or metastable air state at the material surface, which lends itself to a number of unique properties. These activities are catalyzing the development of new materials, applications, and fabrication techniques, as well as collaborations across material science, chemistry, engineering, and medicine given the interdisciplinary nature of this work. The review begins with a discussion of superhydrophobicity, and then explores biomedical applications that are utilizing superhydrophobicity in depth including material selection characteristics, in vitro performance, and in vivo performance. General trends are offered for each application in addition to discussion of conflicting data in the literature, and the review concludes with the authors’ future perspectives on the utility of superhydrophobic surfaces for biomedical applications. PMID:27449946

  2. Biomedical composites materials, manufacturing and engineering

    CERN Document Server

    Davim, J Paulo

    2013-01-01

    Composite materials are engineered materials, made from two or more constituents with significantly different physical or chemical properties which remain separate on a macroscopic level within the finished structure. Due to their special mechanical and physical properties they have the potential to replace conventional materials in various fields such as the biomedical industry.

  3. Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications.

    Science.gov (United States)

    Kaplan, Jonah; Grinstaff, Mark

    2015-08-28

    Superhydrophobic materials, with surfaces possessing permanent or metastable non-wetted states, are of interest for a number of biomedical and industrial applications. Here we describe how electrospinning or electrospraying a polymer mixture containing a biodegradable, biocompatible aliphatic polyester (e.g., polycaprolactone and poly(lactide-co-glycolide)), as the major component, doped with a hydrophobic copolymer composed of the polyester and a stearate-modified poly(glycerol carbonate) affords a superhydrophobic biomaterial. The fabrication techniques of electrospinning or electrospraying provide the enhanced surface roughness and porosity on and within the fibers or the particles, respectively. The use of a low surface energy copolymer dopant that blends with the polyester and can be stably electrospun or electrosprayed affords these superhydrophobic materials. Important parameters such as fiber size, copolymer dopant composition and/or concentration, and their effects on wettability are discussed. This combination of polymer chemistry and process engineering affords a versatile approach to develop application-specific materials using scalable techniques, which are likely generalizable to a wider class of polymers for a variety of applications.

  4. Switchable and responsive surfaces and materials for biomedical applications

    CERN Document Server

    Zhang, Johnathan

    2015-01-01

    Surface modification of biomaterials can ultimately determine whether a material is accepted or rejected from the human body, and a responsive surface can further make the material ""smart"" and ""intelligent"". Switchable and Responsive Surfaces and Materials for Biomedical Applications outlines synthetic and biological materials that are responsive under different stimuli, their surface design and modification techniques, and applicability in regenerative medicine/tissue engineering,  drug delivery, medical devices, and biomedical diagnostics. Part one provides a detailed overview of swit

  5. Dictionary materials engineering, materials testing

    International Nuclear Information System (INIS)

    1994-01-01

    This dictionary contains about 9,500 entries in each part of the following fields: 1) Materials using and selection; 2) Mechanical engineering materials -Metallic materials - Non-metallic inorganic materials - Plastics - Composites -Materials damage and protection; 3) Electrical and electronics materials -Conductor materials - Semiconductors - magnetic materials - Dielectric materials - non-conducting materials; 4) Materials testing - Mechanical methods - Analytical methods - Structure investigation - Complex methods - Measurement of physical properties - Non-destructive testing. (orig.) [de

  6. Development of thermal energy storage materials for biomedical applications.

    Science.gov (United States)

    Shukla, A; Sharma, Atul; Shukla, Manjari; Chen, C R

    2015-01-01

    The phase change materials (PCMs) have been utilized widely for solar thermal energy storage (TES) devices. The quality of these materials to remain at a particular temperature during solid-liquid, liquid-solid phase transition can also be utilized for many biomedical applications as well and has been explored in recent past already. This study reports some novel PCMs developed by them, along with some existing PCMs, to be used for such biomedical applications. Interestingly, it was observed that the heating/cooling properties of these PCMs enhance the quality of a variety of biomedical applications with many advantages (non-electric, no risk of electric shock, easy to handle, easy to recharge thermally, long life, cheap and easily available, reusable) over existing applications. Results of the present study are quite interesting and exciting, opening a plethora of opportunities for more work on the subject, which require overlapping expertise of material scientists, biochemists and medical experts for broader social benefits.

  7. Carbon-based nanomaterials: multifunctional materials for biomedical engineering.

    Science.gov (United States)

    Cha, Chaenyung; Shin, Su Ryon; Annabi, Nasim; Dokmeci, Mehmet R; Khademhosseini, Ali

    2013-04-23

    Functional carbon-based nanomaterials (CBNs) have become important due to their unique combinations of chemical and physical properties (i.e., thermal and electrical conductivity, high mechanical strength, and optical properties), and extensive research efforts are being made to utilize these materials for various industrial applications, such as high-strength materials and electronics. These advantageous properties of CBNs are also actively investigated in several areas of biomedical engineering. This Perspective highlights different types of carbon-based nanomaterials currently used in biomedical applications.

  8. Multifunctional DNA Nano materials for Biomedical Applications

    International Nuclear Information System (INIS)

    Tam, D.Y.; Lo, P.K.; Tam, D.Y.; Lo, P.K.

    2014-01-01

    The rapidly emerging DNA nanotechnology began with pioneer Seeman’s hypothesis that DNA not only can carry genetic information but also can be used as molecular organizer to create well-designed and controllable nanomaterials for applications in materials science, nanotechnology, and biology. DNA-based self-assembly represents a versatile system for nanoscale construction due to the well-characterized conformation of DNA and its predictability in the formation of base pairs. The structural features of nucleic acids form the basis of constructing a wide variety of DNA nanoarchitectures with well-defined shapes and sizes, in addition to controllable permeability and flexibility. More importantly, self-assembled DNA nanostructures can be easily functionalized to construct artificial functional systems with nanometer scale precision for multipurposes. Apparently scientists envision artificial DNA-based nanostructures as tool for drug loading and in vivo targeted delivery because of their abilities in selective encapsulation and stimuli-triggered release of cargo. Herein, we summarize the strategies of creating multidimensional self-assembled DNA nanoarchitectures and review studies investigating their stability, toxicity, delivery efficiency, loading, and control release of cargos in addition to their site-specific targeting and delivery of drug or cargo molecules to cellular systems.

  9. Disclosing discourses: biomedical and hospitality discourses in patient education materials.

    Science.gov (United States)

    Öresland, Stina; Friberg, Febe; Määttä, Sylvia; Öhlen, Joakim

    2015-09-01

    Patient education materials have the potential to strengthen the health literacy of patients. Previous studies indicate that readability and suitability may be improved. The aim of this study was to explore and analyze discourses inherent in patient education materials since analysis of discourses could illuminate values and norms inherent in them. Clinics in Sweden that provided colorectal cancer surgery allowed access to written information and 'welcome letters' sent to patients. The material was analysed by means of discourse analysis, embedded in Derrida's approach of deconstruction. The analysis revealed a biomedical discourse and a hospitality discourse. In the biomedical discourse, the subject position of the personnel was interpreted as the messenger of medical information while that of the patients as the carrier of diagnoses and recipients of biomedical information. In the hospitality discourse, the subject position of the personnel was interpreted as hosts who invite and welcome the patients as guests. The study highlights the need to eliminate paternalism and fosters a critical reflective stance among professionals regarding power and paternalism inherent in health care communication. © 2015 John Wiley & Sons Ltd.

  10. Fluorinated Polymers as Smart Materials for Advanced Biomedical Applications

    Directory of Open Access Journals (Sweden)

    Vanessa F. Cardoso

    2018-02-01

    Full Text Available Fluorinated polymers constitute a unique class of materials that exhibit a combination of suitable properties for a wide range of applications, which mainly arise from their outstanding chemical resistance, thermal stability, low friction coefficients and electrical properties. Furthermore, those presenting stimuli-responsive properties have found widespread industrial and commercial applications, based on their ability to change in a controlled fashion one or more of their physicochemical properties, in response to single or multiple external stimuli such as light, temperature, electrical and magnetic fields, pH and/or biological signals. In particular, some fluorinated polymers have been intensively investigated and applied due to their piezoelectric, pyroelectric and ferroelectric properties in biomedical applications including controlled drug delivery systems, tissue engineering, microfluidic and artificial muscle actuators, among others. This review summarizes the main characteristics, microstructures and biomedical applications of electroactive fluorinated polymers.

  11. Upconversion in Nanostructured Materials: From Optical Tuning to Biomedical Applications.

    Science.gov (United States)

    Sun, Tianying; Ai, Fujin; Zhu, Guangyu; Wang, Feng

    2018-02-16

    Photon upconversion that is characterized by high-energy photon emission followed by lower-energy excitation has been conventionally studied in bulk materials for several decades. This unique nonlinear luminescence process has become a subject of great attention since 2000 when upconverted emission was demonstrated in nanostructured crystals. In comparison with their bulk counterparts, nanostructured materials provide more room for optical fine-tuning by allowing flexible compositional integration and structural engineering. Moreover, the high colloidal stability of nanoparticles coupled with high amenability to surface functionalization opens up a number of new applications for upconversion, especially in the fields of biology and life science. In this focus review, we discuss recent developments in upconversion materials through nanostructural design and review emerging biomedical applications that involve these nanostructured upconversion materials. We also attempt to highlight challenging problems of these nanomaterials that constrain further progress in utilizing upconversion processes. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. Emerging chitin and chitosan nanofibrous materials for biomedical applications

    Science.gov (United States)

    Ding, Fuyuan; Deng, Hongbing; Du, Yumin; Shi, Xiaowen; Wang, Qun

    2014-07-01

    Over the past several decades, we have witnessed significant progress in chitosan and chitin based nanostructured materials. The nanofibers from chitin and chitosan with appealing physical and biological features have attracted intense attention due to their excellent biological properties related to biodegradability, biocompatibility, antibacterial activity, low immunogenicity and wound healing capacity. Various methods, such as electrospinning, self-assembly, phase separation, mechanical treatment, printing, ultrasonication and chemical treatment were employed to prepare chitin and chitosan nanofibers. These nanofibrous materials have tremendous potential to be used as drug delivery systems, tissue engineering scaffolds, wound dressing materials, antimicrobial agents, and biosensors. This review article discusses the most recent progress in the preparation and application of chitin and chitosan based nanofibrous materials in biomedical fields.

  13. Materials testing 1985

    International Nuclear Information System (INIS)

    1985-01-01

    The following subjects were dealt with at the meeting: Testing with vibration loads; Hardness testing; Calibration of test devices and equipment; Test technique for compound materials; Vibration strength testing and expense of experiments; Solving problems in introducing forces into samples and components and process of ambulant materials testing. There are 17 separate abstracts from among 43 lectures. (orig./PW) [de

  14. Flexible Material Systems Testing

    Science.gov (United States)

    Lin, John K.; Shook, Lauren S.; Ware, Joanne S.; Welch, Joseph V.

    2010-01-01

    An experimental program has been undertaken to better characterize the stress-strain characteristics of flexible material systems to support a NASA ground test program for inflatable decelerator material technology. A goal of the current study is to investigate experimental methods for the characterization of coated woven material stiffness. This type of experimental mechanics data would eventually be used to define the material inputs of fluid-structure interaction simulation models. The test methodologies chosen for this stress-strain characterization are presented along with the experimental results.

  15. Materials Test Station

    Data.gov (United States)

    Federal Laboratory Consortium — When completed, the Materials Test Station at the Los Alamos Neutron Science Center will meet mission need. MTS will provide the only fast-reactor-like irradiation...

  16. OBTAINING HYSTERESIS LOOPS AT LOW FREQUENCY FOR CHARACTERIZATION OF MATERIALS TO BE USED IN BIOMEDICAL APPLICATIONS

    Directory of Open Access Journals (Sweden)

    Atika Arshad

    2015-05-01

    Full Text Available The promising development of magnetic sensors in biomedical field demands an appropriate level of understanding of the magnetic properties of the materials used in their fabrication. To date only few of the types of magnetic materials are encountered where their magnetic properties, characterization techniques and magnetization behavior are yet to be explored more suitably in the light of their applications. This research work studies the characterization of materials by using a cost effective and simple circuit consisting of inductive transducer and an OP-AMP as a voltage integrator. In this approach the circuit was simulated using PSPICE and experiments have been conducted to achieve the desired results. The simulation and experimental results are obtained for three test materials namely iron, steel and plastic. The novelty lies in applying the simple circuit for material testing and characterization via obtaining simulation results and validating these results through experiment. The magnetic properties in low external magnetic field are studied with materials under test. The magnetization effect of a magneto-inductive sensor is detected in low frequency range for different magnetic core materials. The results have shown magnetization behaviour of magnetic materials due to the variation of permeability and magnetism. The resulted hysteresis loops appeared to have different shapes for different materials. The magnetic hysteresis loop found for iron core demonstrated a bigger coercive force and larger reversals of magnetism than these of steel core, thus obtaining its magnetic saturation at a larger magnetic field strength. The shape of the hysteresis loop itself is found to be varying upon the nature of the material in use. The resulted magnetization behaviors of the materials proved their possible applicability for use in sensing devices. The key concern of this work is found upon selecting the appropriate magnetic materials at the desired

  17. Engineering artificial machines from designable DNA materials for biomedical applications.

    Science.gov (United States)

    Qi, Hao; Huang, Guoyou; Han, Yulong; Zhang, Xiaohui; Li, Yuhui; Pingguan-Murphy, Belinda; Lu, Tian Jian; Xu, Feng; Wang, Lin

    2015-06-01

    Deoxyribonucleic acid (DNA) emerges as building bricks for the fabrication of nanostructure with complete artificial architecture and geometry. The amazing ability of DNA in building two- and three-dimensional structures raises the possibility of developing smart nanomachines with versatile controllability for various applications. Here, we overviewed the recent progresses in engineering DNA machines for specific bioengineering and biomedical applications.

  18. Development of Biomedical Polymer-Silicate Nanocomposites: A Materials Science Perspective

    Directory of Open Access Journals (Sweden)

    Chia-Jung Wu

    2010-04-01

    Full Text Available Biomedical polymer-silicate nanocomposites have potential to become critically important to the development of biomedical applications, ranging from diagnostic and therapeutic devices, tissue regeneration and drug delivery matrixes to various bio-technologies that are inspired by biology but have only indirect biomedical relation. The fundamental understanding of polymer-nanoparticle interactions is absolutely necessary to control structure-property relationships of materials that need to work within the chemical, physical and biological constraints required by an application. This review summarizes the most recent published strategies to design and develop polymer-silicate nanocomposites (including clay based silicate nanoparticles and bioactive glass nanoparticles for a variety of biomedical applications. Emerging trends in bio-technological and biomedical nanocomposites are highlighted and potential new fields of applications are examined.

  19. Material Testing Device

    Science.gov (United States)

    1993-01-01

    Small Business Innovation Research (SBIR) contracts led to two commercial instruments and a new subsidiary for Physical Sciences, Inc. (PSI). The FAST system, originally developed for testing the effect of space environment on materials, is now sold commercially for use in aging certification of materials intended for orbital operation. The Optical Temperature Monitor was designed for precise measurement of high temperatures on certain materials to be manufactured in space. The original research was extended to the development of a commercial instrument that measures and controls fuel gas temperatures in industrial boilers. PSI created PSI Environmental Instruments to market the system. The company also offers an Aerospace Measurement Service that has evolved from other SBIR contracts.

  20. Awareness about biomedical waste management and knowledge of effective recycling of dental materials among dental students

    Science.gov (United States)

    Ranjan, Rajeev; Pathak, Ruchi; Singh, Dhirendra K.; Jalaluddin, Md.; Kore, Shobha A.; Kore, Abhijeet R.

    2016-01-01

    Aims and Objectives: Biomedical waste management has become a concern with increasing number of dental practitioners in India. Being health care professionals, dentists should be aware regarding safe disposal of biomedical waste and recycling of dental materials to minimize biohazards to the environment. The aim of the present study was to assess awareness regarding biomedical waste management as well as knowledge of effective recycling and reuse of dental materials among dental students. Materials and Methods: This cross-sectional study was conducted among dental students belonging from all dental colleges of Bhubaneswar, Odisha (India) from February 2016 to April 2016. A total of 500 students (208 males and 292 females) participated in the study, which was conducted in two phases. A questionnaire was distributed to assess the awareness of biomedical waste management and knowledge of effective recycling of dental materials, and collected data was examined on a 5-point unipolar scale in percentages to assess the relative awareness regarding these two different categorizes. The Statistical Package for Social Sciences was used to analyzed collected data. Results: Forty-four percent of the dental students were not at all aware about the management of biomedical waste, 22% were moderately aware, 21% slightly aware, 7% very aware, and 5% fell in extremely aware category. Similarly, a higher percentage of participants (61%) were completely unaware regarding recycling and reusing of biomedical waste. Conclusion: There is lack of sufficient knowledge among dental students regarding management of biomedical waste and recycling or reusing of dental materials. Considering its impact on the environment, biomedical waste management requires immediate academic assessment to increase the awareness during training courses. PMID:27891315

  1. Affects of Microgravity on the Polymerization and Material Properties of Biomedical Grade Polymers

    Science.gov (United States)

    Crane, Deborah J.

    2002-01-01

    extended to include other polymers. Polymerization as well as polymer processing in a microgravity environment may affect the length and orientation of the molecular chains, the degree of crosslinking, and distribution of amorphous to crystalline portions of the material, thus changing the ultimate properties of the polymer. Small polymer samples would be produced from the resin for testing and analysis. This research would include the effect of micro-g processing by compression molded vs. ram extruded samples for analysis. Morphological alterations in the material could be monitored using Transmission Electron Microscopy and associated properties such as toughness, density and crystallinity could be determined and compared to terra produced materials using conventional mechanical testing, density gradient columns and calorimetry techniques. If alterations are evident, fatigue testing can be performed on small specimens in order to determine the material's resistance to crack initiation and propagation. number of orthopaedic implant recipients and could be extended for use in robotics and other beneficial applications. Although polymers exhibit the greatest biocompatibility, problems with debris particle generation continue to reduce the effectiveness of UHMWPE as a biomedical material. Further polymer research in a microgravity environment may prove to produce the desired alterations in the materials' morphology and associated properties, therefore providing millions of people with superior orthopaedic implant components and lessen the occurrences of repeat surgery.

  2. Non-animal methodologies within biomedical research and toxicity testing.

    Science.gov (United States)

    Knight, Andrew

    2008-01-01

    Laboratory animal models are limited by scientific constraints on human applicability, and increasing regulatory restrictions, driven by social concerns. Reliance on laboratory animals also incurs marked - and in some cases, prohibitive - logistical challenges, within high-throughput chemical testing programmes, such as those currently underway within Europe and the US. However, a range of non-animal methodologies is available within biomedical research and toxicity testing. These include: mechanisms to enhance the sharing and assessment of existing data prior to conducting further studies, and physicochemical evaluation and computerised modelling, including the use of structure-activity relationships and expert systems. Minimally-sentient animals from lower phylogenetic orders or early developmental vertebral stages may be used, as well as microorganisms and higher plants. A variety of tissue cultures, including immortalised cell lines, embryonic and adult stem cells, and organotypic cultures, are also available. In vitro assays utilising bacterial, yeast, protozoal, mammalian or human cell cultures exist for a wide range of toxic and other endpoints. These may be static or perfused, and may be used individually, or combined within test batteries. Human hepatocyte cultures and metabolic activation systems offer potential assessment of metabolite activity and organ-organ interaction. Microarray technology may allow genetic expression profiling, increasing the speed of toxin detection, well prior to more invasive endpoints. Enhanced human clinical trials utilising micro- dosing, staggered dosing, and more representative study populations and durations, as well as surrogate human tissues, advanced imaging modalities and human epidemiological, sociological and psycho- logical studies, may increase our understanding of illness aetiology and pathogenesis, and facilitate the development of safe and effective pharmacologic interventions. Particularly when human tissues

  3. Escherichia coli adhesion, biofilm development and antibiotic susceptibility on biomedical materials.

    Science.gov (United States)

    Gomes, L C; Silva, L N; Simões, M; Melo, L F; Mergulhão, F J

    2015-04-01

    The aim of this work was to test materials typically used in the construction of medical devices regarding their influence in the initial adhesion, biofilm development and antibiotic susceptibility of Escherichia coli biofilms. Adhesion and biofilm development was monitored in 12-well microtiter plates containing coupons of different biomedical materials--silicone (SIL), stainless steel (SS) and polyvinyl chloride (PVC)--and glass (GLA) as control. The susceptibility of biofilms to ciprofloxacin and ampicillin was assessed, and the antibiotic effect in cell morphology was observed by scanning electron microscopy. The surface hydrophobicity of the bacterial strain and materials was also evaluated from contact angle measurements. Surface hydrophobicity was related with initial E. coli adhesion and subsequent biofilm development. Hydrophobic materials, such as SIL, SS, and PVC, showed higher bacterial colonization than the hydrophilic GLA. Silicone was the surface with the greatest number of adhered cells and the biofilms formed on this material were also less susceptible to both antibiotics. It was found that different antibiotics induced different levels of elongation on E. coli sessile cells. Results revealed that, by affecting the initial adhesion, the surface properties of a given material can modulate biofilm buildup and interfere with the outcome of antimicrobial therapy. These findings raise the possibility of fine-tuning surface properties as a strategy to reach higher therapeutic efficacy. © 2014 Wiley Periodicals, Inc.

  4. Novel Electrochemical Test Bench for Evaluating the Functional Fatigue Life of Biomedical Alloys

    Science.gov (United States)

    Ijaz, M. F.; Dubinskiy, S.; Zhukova, Y.; Korobkova, A.; Pustov, Y.; Brailovski, V.; Prokoshkin, S.

    2017-08-01

    The aim of the present work was first to develop and validate a test bench that simulates the in vitro conditions to which the biomedical implants will be actually subjected in vivo. For the preliminary application assessments, the strain-controlled fatigue tests of biomedically pure Ti and Ti-Nb-Zr alloy in simulated body fluid were undertaken. The in situ open-circuit potential measurements from the test bench demonstrated a strong dependence on the dynamic cycling and kind of material under testing. The results showed that during fatigue cycling, the passive oxide film formed on the surface of Ti-Nb-Zr alloy was more resistant to fatigue degradation when compared with pure Ti. The Ti-Nb-Zr alloy exhibited prolonged fatigue life when compared with pure Ti. The fractographic features of both materials were also characterized using scanning electron microscopy. The electrochemical results and the fractographic evidence confirmed that the prolonged functional fatigue life of the Ti-Nb-Zr alloy is apparently ascribable to the reversible martensitic phase transformation.

  5. Composite Material Mirror Testing

    Science.gov (United States)

    2000-01-01

    In this photograph, the composite material mirror is tested in the X-Ray Calibration Facility at the Marshall Space Flight Center for the James Webb Space Telescope (JWST). The mirror test conducted was to check the ability to accurately model and predict the cryogenic performance of complex mirror systems, and the characterization of cryogenic dampening properties of beryllium. The JWST, a next generation successor to the Hubble Space Telescope (HST), was named in honor of James W. Webb, NASA's second administrator, who led NASA in the early days of the fledgling Aerospace Agency. Scheduled for launch in 2010 aboard an expendable launch vehicle, the JWST will be able to look deeper into the universe than the HST because of the increased light-collecting power of its larger mirror and the extraordinary sensitivity of its instrument to infrared light.

  6. Japanese research and development on metallic biomedical, dental, and healthcare materials

    Science.gov (United States)

    Niinomi, Mitsuo; Hanawa, Takao; Narushima, Takayuki

    2005-04-01

    There is considerable demand for metallic materials for use in medical and dental devices. Metals and alloys are widely used as biomedical materials and are indispensable in the medical field. In dentistry, metal is used for restorations, orthodontic wires, and dental implants. This article describes R&D on metallic biomaterials primarily conducted by the members of the Japan Institute of Metals.

  7. Piezoelectric materials as stimulatory biomedical materials and scaffolds for bone repair.

    Science.gov (United States)

    Tandon, Biranche; Blaker, Jonny J; Cartmell, Sarah H

    2018-04-16

    The process of bone repair and regeneration requires multiple physiological cues including biochemical, electrical and mechanical - that act together to ensure functional recovery. Myriad materials have been explored as bioactive scaffolds to deliver these cues locally to the damage site, amongst these piezoelectric materials have demonstrated significant potential for tissue engineering and regeneration, especially for bone repair. Piezoelectric materials have been widely explored for power generation and harvesting, structural health monitoring, and use in biomedical devices. They have the ability to deform with physiological movements and consequently deliver electrical stimulation to cells or damaged tissue without the need of an external power source. Bone itself is piezoelectric and the charges/potentials it generates in response to mechanical activity are capable of enhancing bone growth. Piezoelectric materials are capable of stimulating the physiological electrical microenvironment, and can play a vital role to stimulate regeneration and repair. This review gives an overview of the association of piezoelectric effect with bone repair, and focuses on state-of-the-art piezoelectric materials (polymers, ceramics and their composites), the fabrication routes to produce piezoelectric scaffolds, and their application in bone repair. Important characteristics of these materials from the perspective of bone tissue engineering are highlighted. Promising upcoming strategies and new piezoelectric materials for this application are presented. Electrical stimulation/electrical microenvironment are known effect the process of bone regeneration by altering the cellular response and are crucial in maintaining tissue functionality. Piezoelectric materials, owing to their capability of generating charges/potentials in response to mechanical deformations, have displayed great potential for fabricating smart stimulatory scaffolds for bone tissue engineering. The growing

  8. Carbon-Based Nanomaterials: Multi-Functional Materials for Biomedical Engineering

    Science.gov (United States)

    Cha, Chaenyung; Shin, Su Ryon; Annabi, Nasim; Dokmeci, Mehmet R.; Khademhosseini, Ali

    2013-01-01

    Functional carbon-based nanomaterials (CBNs) have become important due to their unique combinations of chemical and physical properties (i.e., thermal and electrical conductivity, high mechanical strength, and optical properties), extensive research efforts are being made to utilize these materials for various industrial applications, such as high-strength materials and electronics. These advantageous properties of CBNs are also actively investigated in several areas of biomedical engineering. This Perspective highlights different types of carbon-based nanomaterials currently used in biomedical applications. PMID:23560817

  9. Characterization of Powder Metallurgy Processed Pure Magnesium Materials for Biomedical Applications

    Directory of Open Access Journals (Sweden)

    Matěj Březina

    2017-10-01

    Full Text Available Magnesium with its mechanical properties and nontoxicity is predetermined as a material for biomedical applications; however, its high reactivity is a limiting factor for its usage. Powder metallurgy is one of the promising methods for the enhancement of material mechanical properties and, due to the introduced plastic deformation, can also have a positive influence on corrosion resistance. Pure magnesium samples were prepared via powder metallurgy. Compacting pressures from 100 MPa to 500 MPa were used for samples’ preparation at room temperature and elevated temperatures. The microstructure of the obtained compacts was analyzed in terms of microscopy. The three-point bendisng test and microhardness testing were adopted to define the compacts’ mechanical properties, discussing the results with respect to fractographic analysis. Electrochemical corrosion properties analyzed with electrochemical impedance spectroscopy carried out in HBSS (Hank’s Balanced Salt Solution and enriched HBSS were correlated with the metallographic analysis of the corrosion process. Cold compacted materials were very brittle with low strength (up to 50 MPa and microhardness (up to 50 HV (load: 0.025 kg and degraded rapidly in both solutions. Hot pressed materials yielded much higher strength (up to 250 MPa and microhardness (up to 65 HV (load: 0.025 kg, and the electrochemical characteristics were significantly better when compared to the cold compacted samples. Temperatures of 300 °C and 400 °C and high compacting pressures from 300 MPa to 500 MPa had a positive influence on material bonding, mechanical and electrochemical properties. A compacting temperature of 500 °C had a detrimental effect on material compaction when using pressure above 200 MPa.

  10. Biomedical materials, devices and drug delivery systems by radiation techniques

    International Nuclear Information System (INIS)

    Kaetsu, Isao.

    1996-01-01

    The study of radiation polymerization in a super-cooled state started in 1966 and has been applied to the immobilization of biofunctional materials since 1973. In the last twenty years, application has been concentrated on the immobilization of drugs and hormones for the purpose of drug delivery systems. Very recently, the author has proposed a concept of environmental signal responsive chemical delivery system, as a new generation of controlled release and delivery systems. The study and development of materials, devices and systems is described. The signal responsive delivery system consists of a sensor part and a controlled delivery part. Therefore, the use of immobilization techniques for the biochip sensor and the hydrogel actuator has been investigated. As a future goal, systems for brain research are to be designed and studied. (author)

  11. Periodical Microstructures Based on Novel Piezoelectric Material for Biomedical Applications

    Directory of Open Access Journals (Sweden)

    Giedrius Janusas

    2015-12-01

    Full Text Available A novel cantilever type piezoelectric sensing element was developed. Cost-effective and simple fabrication design allows the use of this element for various applications in the areas of biomedicine, pharmacy, environmental analysis and biosensing. This paper proposes a novel piezoelectric composite material whose basic element is PZT and a sensing platform where this material was integrated. Results showed that a designed novel cantilever-type element is able to generate a voltage of up to 80 µV at 50 Hz frequency. To use this element for sensing purposes, a four micron periodical microstructure was imprinted. Silver nanoparticles were precipitated on the grating to increase the sensitivity of the designed element, i.e., Surface Plasmon Resonance (SPR effect appears in the element. To tackle some issues (a lack of sensitivity, signal delays the element must have certain electronic and optical properties. One possible solution, proposed in this paper, is a combination of piezoelectricity and SPR in a single element.

  12. Biomedical and Microbiological Applications of Bio-Based Porous Materials: A Review

    Directory of Open Access Journals (Sweden)

    T. M. S. Udenni Gunathilake

    2017-04-01

    Full Text Available Extensive employment of biomaterials in the areas of biomedical and microbiological applications is considered to be of prime importance. As expected, oil based polymer materials were gradually replaced by natural or synthetic biopolymers due to their well-known intrinsic characteristics such as biodegradability, non-toxicity and biocompatibility. Literature on this subject was found to be expanding, especially in the areas of biomedical and microbiological applications. Introduction of porosity into a biomaterial broadens the scope of applications. In addition, increased porosity can have a beneficial effect for the applications which exploit their exceptional ability of loading, retaining and releasing of fluids. Different applications require a unique set of pore characteristics in the biopolymer matrix. Various pore morphologies have different characteristics and contribute different performances to the biopolymer matrix. Fabrication methods for bio-based porous materials more related to the choice of material. By choosing the appropriate combination of fabrication technique and biomaterial employment, one can obtain tunable pore characteristic to fulfill the requirements of desired application. In our previous review, we described the literature related to biopolymers and fabrication techniques of porous materials. This paper we will focus on the biomedical and microbiological applications of bio-based porous materials.

  13. Materials and test methods

    International Nuclear Information System (INIS)

    Kase, M.B.

    1985-01-01

    The objective of this study was to provide, in cooperation with ORNL and LANL, specimens required for studies to develop organic insulators having the cryogenic neutron irradiation resistance required for MFE systems utilizing superconducting magnetic confinement. To develop test methods and analytical procedures for assessing radiation damage. To stimulate and participate in international cooperation directed toward accomplishing these objectives. The system for producing uniaxially reinforced, 3-4 mm (0.125 in) diameter rod specimens has been refined and validated by production of excellent quality specimens using liquid-mix epoxy resin systems. The methodology is undergoing further modification to permit use of hot-melt epoxy and polyimide resin systems as will be required for the experimental program to be conducted in the NLTNIF reactor at ORNL. Preliminary studies indicate that short beam and torsional shear test methods will be useful in evaluating radiation degradation. Development of these and other applicable test methods are continuing. A cooperative program established with laboratories in Japan and in England has resulted in the production and testing of specimens having an identical configuration

  14. Lignocellulosic Biomass Derived Functional Materials: Synthesis and Applications in Biomedical Engineering.

    Science.gov (United States)

    Zhang, Lei; Peng, Xinwen; Zhong, Linxin; Chua, Weitian; Xiang, Zhihua; Sun, Runcang

    2017-09-18

    The pertinent issue of resources shortage arising from global climate change in the recent years has accentuated the importance of materials that are environmental friendly. Despite the merits of current material like cellulose as the most abundant natural polysaccharide on earth, the incorporation of lignocellulosic biomass has the potential to value-add the recent development of cellulose-derivatives in drug delivery systems. Lignocellulosic biomass, with a hierarchical structure, comprised of cellulose, hemicellulose and lignin. As an excellent substrate that is renewable, biodegradable, biocompatible and chemically accessible for modified materials, lignocellulosic biomass sets forth a myriad of applications. To date, materials derived from lignocellulosic biomass have been extensively explored for new technological development and applications, such as biomedical, green electronics and energy products. In this review, chemical constituents of lignocellulosic biomass are first discussed before we critically examine the potential alternatives in the field of biomedical application. In addition, the pretreatment methods for extracting cellulose, hemicellulose and lignin from lignocellulosic biomass as well as their biological applications including drug delivery, biosensor, tissue engineering etc will be reviewed. It is anticipated there will be an increasing interest and research findings in cellulose, hemicellulose and lignin from natural resources, which help provide important directions for the development in biomedical applications. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  15. Materials Testing - Digital Ecology

    Directory of Open Access Journals (Sweden)

    Seth Wiley

    2013-03-01

    Full Text Available Access to credible building product performance information throughout the design and construction process is critical to enable project development, vet product selections, ensure as-built quality, and successfully complete construction. This is common knowledge and part of common practice for nearly all parties involved in design and construction. The sources of such information can range from vernacular to formal – from common practice to special reference. The focus of this paper is one of the more formal or specialized information sources, performance testing, as well as how such performance testing information can be better used. This paper’s goals are to familiarize the reader with performance testing and to depict a new kind of valuable informational tool (digital ecology. Reference to pertinent nomenclature, description of a real world example, and detailed description of such an informational tool’s values will be provided.The major content of this paper was developed during project-based work and firm-funded internal research at point b design, ltd. over approximately the previous 4 years. The phrase ‘digital ecology’ as herein used is a new concept proposed by the author. The analysis contained in this paper could be applied to the field of operations and maintenance as it is herein applied to design and construction; however, operations and maintenance is beyond the scope of this paper and may be addressed in future papers. It is my hope that this paper will contribute to tangible and real improvements of the built environment via continued, positive development within academic and professional practice.

  16. Composite film fabricated on biomedical material with corona streamer plasma processing to mitigate bacterial adhesion

    Science.gov (United States)

    Alhamarneh, Ibrahim; Pedrow, Patrick; Eskhan, Asma; Abu-Lail, Nehal

    2011-10-01

    Composite films might control bacterial adhesion and concomitant biofouling that afflicts biomedical materials. Different size molecules of polyethylene glycol (PEG) with nominal molecular weights 600, 2000, and 20000 g/mol were used to synthesize composite films with plasma processing and dip-coating procedures on surgical-grade 316L stainless steel. Before dip-coating, the substrate was pre-coated with plasma-polymerized di(ethylene glycol) vinyl ether (pp-EO2V) in an atmospheric pressure corona streamer plasma reactor. The PEG dip-coating step followed immediately in the same chamber due to the finite lifetime of radicals associated with freshly deposited pp-EO2V. Morphology of the composite film was investigated with an ESEM. FTIR confirmed incorporation of pp-EO2V and PEG species into the composite film. More investigations on the composite film were conducted by XPS measurements. Adhesion of the composite film was evaluated with a standard peel-off test. Stability of the composite film in buffer solution was evaluated by AFM. AFM was also used to measure the film roughness and thickness. Polar and non-polar contact angle measurements were included.

  17. Testing of Replacement Bag Material

    International Nuclear Information System (INIS)

    Laurinat, J.E.

    1998-01-01

    Recently, the FB-Line bagout material was changed to simplify the processing of sand, slag, and crucible.The results of the strength tests and the outgassing measurements and calculations demonstrate that the proposed replacement nylon bag materials (HRMP and orange anti-static material) are acceptable substitutes for LDPE and the original nylon with respect to mechanical properties

  18. Synthesis, toxicity, biocompatibility, and biomedical applications of graphene and graphene-related materials

    Directory of Open Access Journals (Sweden)

    Gurunathan S

    2016-05-01

    Full Text Available Sangiliyandi Gurunathan, Jin-Hoi Kim Stem Cell and Regenerative Biology, Konkuk University, Seoul, Republic of Korea Abstract: Graphene is a two-dimensional atomic crystal, and since its development it has been applied in many novel ways in both research and industry. Graphene possesses unique properties, and it has been used in many applications including sensors, batteries, fuel cells, supercapacitors, transistors, components of high-strength machinery, and display screens in mobile devices. In the past decade, the biomedical applications of graphene have attracted much interest. Graphene has been reported to have antibacterial, antiplatelet, and anticancer activities. Several salient features of graphene make it a potential candidate for biological and biomedical applications. The synthesis, toxicity, biocompatibility, and biomedical applications of graphene are fundamental issues that require thorough investigation in any kind of applications related to human welfare. Therefore, this review addresses the various methods available for the synthesis of graphene, with special reference to biological synthesis, and highlights the biological applications of graphene with a focus on cancer therapy, drug delivery, bio-imaging, and tissue engineering, together with a brief discussion of the challenges and future perspectives of graphene. We hope to provide a comprehensive review of the latest progress in research on graphene, from synthesis to applications. Keywords: biomedical applications, cancer therapy, drug delivery, graphene, graphene-related materials, tissue engineering, toxicity 

  19. Developing test materials for dyscalculia

    DEFF Research Database (Denmark)

    Lindenskov, Lena; Bent, Lindhardt,

    Aims, requirements and context for the development of test materials for dyscalculia are analyzed. The test materials are to be used for Grade 4 pupils in Danish primary schools. Preliminary results are presented from focus group interview with adolescents and adults, who see themselves as being...

  20. A novel multifunctional biomedical material based on polyacrylonitrile: Preparation and characterization.

    Science.gov (United States)

    Wu, Huan-ling; Bremner, David H; Li, He-yu; Shi, Qi-quan; Wu, Jun-zi; Xiao, Rui-qiu; Zhu, Li-min

    2016-05-01

    Wet spun microfibers have great potential in the design of multifunctional controlled release materials. Curcumin (Cur) and vitamin E acetate (Vit. E Ac) were used as a model drug system to evaluate the potential application of the drug-loaded microfiber system for enhanced delivery. The drugs and polyacrylonitrile (PAN) were blended together and spun to produce the target drug-loaded microfiber using an improved wet-spinning method and then the microfibers were successfully woven into fabrics. Morphological, mechanical properties, thermal behavior, drug release performance characteristics, and cytocompatibility were determined. The drug-loaded microfiber had a lobed "kidney" shape with a height of 50-100 μm and width of 100-200 μm. The addition of Cur and Vit. E Ac had a great influence on the surface and cross section structure of the microfiber, leading to a rough surface having microvoids. X-ray diffraction and Fourier transform infrared spectroscopy indicated that the drugs were successfully encapsulated and dispersed evenly in the microfilament fiber. After drug loading, the mechanical performance of the microfilament changed, with the breaking strength improved slightly, but the tensile elongation increased significantly. Thermogravimetric results showed that the drug load had no apparent adverse effect on the thermal properties of the microfibers. However, drug release from the fiber, as determined through in-vitro experiments, is relatively low and this property is maintained over time. Furthermore, in-vitro cytocompatibility testing showed that no cytotoxicity on the L929 cells was found up to 5% and 10% respectively of the theoretical drug loading content (TDLC) of curcumin and vitamin E acetate. This study provides reference data to aid the development of multifunctional textiles and to explore their use in the biomedical material field. Copyright © 2016 Elsevier B.V. All rights reserved.

  1. Laser-assisted development of titanium alloys: the search for new biomedical materials

    Science.gov (United States)

    Almeida, Amelia; Gupta, Dheeraj; Vilar, Rui

    2011-02-01

    Ti-alloys used in prosthetic applications are mostly alloys initially developed for aeronautical applications, so their behavior was not optimized for medical use. A need remains to design new alloys for biomedical applications, where requirements such as biocompatibility, in-body durability, specific manufacturing ability, and cost effectiveness are considered. Materials for this application must present excellent biocompatibility, ductility, toughness and wear and corrosion resistance, a large laser processing window and low sensitivity to changes in the processing parameters. Laser deposition has been investigated in order to access its applicability to laser based manufactured implants. In this study, variable powder feed rate laser cladding has been used as a method for the combinatorial investigation of new alloy systems that offers a unique possibility for the rapid and exhaustive preparation of a whole range of alloys with compositions variable along a single clad track. This method was used as to produce composition gradient Ti-Mo alloys. Mo has been used since it is among the few elements biocompatible, non-toxic β-Ti phase stabilizers. Alloy tracks with compositions in the range 0-19 wt.%Mo were produced and characterized in detail as a function of composition using microscale testing procedures for screening of compositions with promising properties. Microstructural analysis showed that alloys with Mo content above 8% are fully formed of β phase grains. However, these β grains present a cellular substructure that is associated to a Ti and Mo segregation pattern that occurs during solidification. Ultramicroindentation tests carried out to evaluate the alloys' hardness and Young's modulus showed that Ti-13%Mo alloys presented the lowest hardness and Young's modulus (70 GPa) closer to that of bone than common Ti alloys, thus showing great potential for implant applications.

  2. Titanium–35niobium alloy as a potential material for biomedical implants: In vitro study

    Energy Technology Data Exchange (ETDEWEB)

    Perez de Andrade, Dennia; Marotta Reis de Vasconcellos, Luana; Chaves Silva Carvalho, Isabel; Ferraz de Brito Penna Forte, Lilibeth; Souza Santos, Evelyn Luzia de [Department of Bioscience and Oral Diagnosis, Institute of Science and Technology, UNESP — Univ Estadual Paulista, State University of São Paulo (UNESP), Av. Engenheiro Francisco José Longo, 777, São José dos Campos 12245-000, SP (Brazil); Falchete do Prado, Renata, E-mail: renatafalchete@hotmail.com [Department of Bioscience and Oral Diagnosis, Institute of Science and Technology, UNESP — Univ Estadual Paulista, State University of São Paulo (UNESP), Av. Engenheiro Francisco José Longo, 777, São José dos Campos 12245-000, SP (Brazil); Santos, Dalcy Roberto dos; Alves Cairo, Carlos Alberto [Division of Materials, Air and Space Institute, CTA, Praça Mal. do Ar Eduardo Gomes, 14, São José dos Campos 12904-000, SP (Brazil); Rodarte Carvalho, Yasmin [Department of Bioscience and Oral Diagnosis, Institute of Science and Technology, UNESP — Univ Estadual Paulista, State University of São Paulo (UNESP), Av. Engenheiro Francisco José Longo, 777, São José dos Campos 12245-000, SP (Brazil)

    2015-11-01

    Research on new titanium alloys and different surface topographies aims to improve osseointegration. The objective of this study is to analyze the behavior of osteogenic cells cultivated on porous and dense samples of titanium–niobium alloys, and to compare them with the behavior of such type of cells on commercial pure titanium. Samples prepared using powder metallurgy were characterized using scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), X-ray diffraction (XRD), and metallographic and profilometer analyses. Osteogenic cells from newborn rat calvaria were plated over different groups: dense or porous samples composed of Ti or Ti–35niobium (Nb). Cell adhesion, cell proliferation, MTT assay, cell morphology, protein total content, alkaline phosphatase activity, and mineralization nodules were assessed. Results from XRD and EDS analysis confirmed the presence of Ti and Nb in the test alloy. Metallographic analysis revealed interconnected pores, with pore size ranging from 138 to 150 μm. The profilometer analysis detected the greatest rugosity within the dense alloy samples. In vitro tests revealed similar biocompatibility between Ti–35Nb and Ti; furthermore, it was possible to verify that the association of porous surface topography and the Ti–35Nb alloy positively influenced mineralized matrix formation. We propose that the Ti–35Nb alloy with porous topography constitutes a biocompatible material with great potential for use in biomedical implants. - Highlights: • Powder metallurgy is effective in producing porous biomaterials. • Ti–35Nb alloy improved mineralized matrix formation. • Porous surface favored a multidirectional pattern of cell spreading. • Porous surface Ti–35Nb alloy appears to be more favorable to bone formation than existing alloys.

  3. Titanium–35niobium alloy as a potential material for biomedical implants: In vitro study

    International Nuclear Information System (INIS)

    Perez de Andrade, Dennia; Marotta Reis de Vasconcellos, Luana; Chaves Silva Carvalho, Isabel; Ferraz de Brito Penna Forte, Lilibeth; Souza Santos, Evelyn Luzia de; Falchete do Prado, Renata; Santos, Dalcy Roberto dos; Alves Cairo, Carlos Alberto; Rodarte Carvalho, Yasmin

    2015-01-01

    Research on new titanium alloys and different surface topographies aims to improve osseointegration. The objective of this study is to analyze the behavior of osteogenic cells cultivated on porous and dense samples of titanium–niobium alloys, and to compare them with the behavior of such type of cells on commercial pure titanium. Samples prepared using powder metallurgy were characterized using scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), X-ray diffraction (XRD), and metallographic and profilometer analyses. Osteogenic cells from newborn rat calvaria were plated over different groups: dense or porous samples composed of Ti or Ti–35niobium (Nb). Cell adhesion, cell proliferation, MTT assay, cell morphology, protein total content, alkaline phosphatase activity, and mineralization nodules were assessed. Results from XRD and EDS analysis confirmed the presence of Ti and Nb in the test alloy. Metallographic analysis revealed interconnected pores, with pore size ranging from 138 to 150 μm. The profilometer analysis detected the greatest rugosity within the dense alloy samples. In vitro tests revealed similar biocompatibility between Ti–35Nb and Ti; furthermore, it was possible to verify that the association of porous surface topography and the Ti–35Nb alloy positively influenced mineralized matrix formation. We propose that the Ti–35Nb alloy with porous topography constitutes a biocompatible material with great potential for use in biomedical implants. - Highlights: • Powder metallurgy is effective in producing porous biomaterials. • Ti–35Nb alloy improved mineralized matrix formation. • Porous surface favored a multidirectional pattern of cell spreading. • Porous surface Ti–35Nb alloy appears to be more favorable to bone formation than existing alloys

  4. Materials interaction test summary description

    International Nuclear Information System (INIS)

    Krogness, J.C.

    1980-01-01

    The Materials Interaction Test is designed to provide early scoping data on host rock performance and interaction between nuclear waste canister materials and host repository media under conditions representative of expected disposal environments. Capsules containing these materials were put in a spent fuel assembly and subsequently placed in a disposal test to study behavior in a low-level radiation environment at temperatures expected to range between 300 and 400 0 F. Thermal control capsules are being exposed in laboratory furnaces to allow a determination and separation of thermal and radiation effects. Post-test specimen examinations are planned to determine material property changes and interaction effects and provide data for understanding the effectiveness of host rock, canister, and cladding materials in long-term waste isolation

  5. Biomedical and Clinical Importance of Mussel-Inspired Polymers and Materials

    Directory of Open Access Journals (Sweden)

    Nagendra Kumar Kaushik

    2015-11-01

    Full Text Available The substance secreted by mussels, also known as nature’s glue, is a type of liquid protein that hardens rapidly into a solid water-resistant adhesive material. While in seawater or saline conditions, mussels can adhere to all types of surfaces, sustaining its bonds via mussel adhesive proteins (MAPs, a group of proteins containing 3,4-dihydroxyphenylalanine (DOPA and catecholic amino acid. Several aspects of this adhesion process have inspired the development of various types of synthetic materials for biomedical applications. Further, there is an urgent need to utilize biologically inspired strategies to develop new biocompatible materials for medical applications. Consequently, many researchers have recently reported bio-inspired techniques and materials that show results similar to or better than those shown by MAPs for a range of medical applications. However, the susceptibility to oxidation of 3,4-dihydroxyphenylalanine poses major challenges with regard to the practical translation of mussel adhesion. In this review, various strategies are discussed to provide an option for DOPA/metal ion chelation and to compensate for the limitations imposed by facile 3,4-dihydroxyphenylalanine autoxidation. We discuss the anti-proliferative, anti-inflammatory, anti-microbial activity, and adhesive behaviors of mussel bio-products and mussel-inspired materials (MIMs that make them attractive for synthetic adaptation. The development of biologically inspired adhesive interfaces, bioactive mussel products, MIMs, and arising areas of research leading to biomedical applications are considered in this review.

  6. Electrochemically deposited conducting polymers for reliable biomedical interfacing materials: Formulation, mechanical characterization, and failure analysis

    Science.gov (United States)

    Qu, Jing

    Conjugated polymers such as poly(3,4-ethylenedioxythiophene) (PEDOT) are of interest for a variety of applications including interfaces between electronic biomedical devices and living tissue. These polymers provide an improved interface compared to metal and semiconducting electrodes because of their ionic conductivity, relatively lower stiffness, and ability to incorporate biological molecules. Even though the signal transfer and biocompatibility of conjugated polymers are superior compared as the biointerfacing materials, the durability has been the weakest part for the long-term applications. Even though some efforts have been made to improve the durability of conjugated polymers, little quantitative information of the improved cohesion, adhesion and durability has been reported. In this thesis, the methods of improving the durability of conjugated polymer films, especially PEDOT, were investigated, including alternating the processing methods and components in synthesis. The 7-month in vivo testing showed that the durability of PEDOT films still needed to be improved. As a coating for biosignal transfer, the cohesion, adhesion and electrochemical stability of PEDOT are vital to determine the long-term performance. Not much information hd been developed around the cohesion and adhesion. A thin film cracking method was developed to measure the stiffness, strength and the interfacial shear strength (adhesion) of electrochemically deposited PEDOT. The estimated Young’s modulus of the PEDOT films was 2.6 ± 1.4 GPa, and the strain to failure was around 2%. The tensile strength was measured to be 56 ± 27 MPa. The effectiveness of crosslinker and adhesion promoter was demonstrated by this method. It was shown that 5 mole% addition of a tri-functional EDOT crosslinker (EPh) increased the tensile strength of the films to 283 ± 67 MPa, while the strain to failure remained about the same (2%). With the modification of EDOT-acid to the surface of stainless steel

  7. Composite materials: Testing and design

    Science.gov (United States)

    Whitcomb, John D. (Editor)

    1988-01-01

    The present conference discusses topics in the analysis of composite structures, composite materials' impact and compression behavior, composite materials characterization methods, composite failure mechanisms, NDE methods for composites, and filament-wound and woven composite materials' fabrication. Attention is given to the automated design of a composite plate for damage tolerance, the effects of adhesive layers on composite laminate impact damage, instability-related delamination growth in thermoset and thermoplastic composites, a simple shear fatigue test for unidirectional E-glass epoxy, the growth of elliptic delaminations in laminates under cyclic transverse shear, and the mechanical behavior of braided composite materials.

  8. Testing Requirements for Refractory Materials

    Science.gov (United States)

    Calle, Luz Marina; Hintze, Paul E.; Parlier, Christopher R.; Curran, Jerome P.; Kolody, Mark R.; Sampson, Jeffrey W,; Montgomery, Eliza M.

    2012-01-01

    Launch Pads 39A and 39B currently use refractory material (Fondu Fyre) in the flame trenches. This material was initially approved for the Saturn program. This material had a lifetime of 10years according to the manufacturer, and it has been used for over 40 years. As a consequence, the Fondu Fyre at Launch Complex 39 requires repair subsequent to almost every launch. A review of the literature indicates that the gunned Fondu Fyre refractory product (WA-1 G) was never tested prior to use. With the recent severe damage to the flame trenches, a new refractory material is sought to replace Fondu Fyre. In order to replace Fondu Fyre, a methodology to test and evaluate refractory products was developed. This paper outlines this methodology and discusses current testing requirements, as well as the laboratory testing that might be required. Furthermore, this report points out the necessity for subscale testing, the locations where this testing can be performed, and the parameters that will be necessary to qualify a product. The goal is to identify a more durable refractory material that has physical, chemical, and thermal properties suitable to withstand the harsh environment of the launch pads at KSC.

  9. Materials processing towards development of rapid prototyping technology for manufacturing biomedical implants

    Science.gov (United States)

    Pekin, Senol

    2000-10-01

    Materials processing towards development of fused deposition of materials (FDM) method for manufacturing biomedical implants has been studied experimentally. Main processing steps consisted of thermoplastic binder development in the ethylene vinyl acetate (EVA)-microcrystalline wax system, feedstock extrusion, characterization and optimization of binder degradation, and sintering of calcium deficient hydroxyapatite. Differential scanning calorimetry (DSC) revealed that the melting index (MI) of the copolymer affects the temperature location of the solidification exotherm, whereas the effect on the temperature location of the melting endotherm was negligible. Nonisothermal measurement of viscosity of different blends as a function of VA content of the EVA component revealed that the microcrystalline wax is compatible with 25--14% VA-containing EVA grades. Further DSC analysis revealed that co-crystallization leads to compatible EVA-microcrystalline wax blends. A typical binder formulation that was developed in the present work has a viscosity of about 700 cP at 140°C, a compressive yield strength of 6 MPa and an elastic modulus of about 600 MPa, and contained 15--20% EVA and 80--85% microcrystalline wax. Various filaments with a nominal diameter of 1.8 mm were extruded by using such a binder, and calcium pyro-phosphate powder that had a distribution modulus of about 0.37. Measurement of physical dimensions of the filament revealed that fluid state can be achieved in the filaments. Simultaneous thermal analysis of degradation characteristics of the typical binder formulations revealed that degradation sequence is oxidation of the hydrocarbons, evaporation of the hydrocarbons, degradation of the vinyl acetate, and degradation of the ethylene chain. A rate controlled binder removal system was developed and used in order to optimize the binder removal schedule. Sintering of gel-cast calcium hydroxyapatite was studied by means of thermal analysis, XRD, mechanical

  10. Endovascular Device Testing with Particle Image Velocimetry Enhances Undergraduate Biomedical Engineering Education

    Science.gov (United States)

    Nair, Priya; Ankeny, Casey J.; Ryan, Justin; Okcay, Murat; Frakes, David H.

    2016-01-01

    We investigated the use of a new system, HemoFlow™, which utilizes state of the art technologies such as particle image velocimetry to test endovascular devices as part of an undergraduate biomedical engineering curriculum. Students deployed an endovascular stent into an anatomical model of a cerebral aneurysm and measured intra-aneurysmal flow…

  11. A Study of Hybrid Composite Hydroxyapatite (HA-Geopolymers as a Material for Biomedical Application

    Directory of Open Access Journals (Sweden)

    Saleha

    2017-01-01

    Full Text Available The main purpose of this research is to study the physical properties and microstructure characters of hybrid composites HA-geopolymers as a material for biomedical application. Hybrid composite HA–geopolymers were produced through alkaline activation method of metakaolin as a matrix and HA as the filler. HA was synthesized from eggshell particles by using a precipitation method. The addition of HA in metakaolin paste was varied from 0.5%, 1.0%, 1.5%, and 2.0% relative the weight of metakaolin. FTIR was used to examine the absorption bands the composites. X-ray diffraction (XRD was used to study the crystal structure of the starting and the resulting materials. Scanning Electron Microscopy-Energy Dispersive Spectroscopy (SEM-EDS was used to investigate the surface morphology of the composites. The thermal properties of the samples was examined by means of Differential Scanning Calorimetry (DSC. Capacitance measurement was conducted to investigate the bioactive properties of HA. The study results suggest that hybrid composite HA-geopolymers has a potential to be applied as a biomedical such as biosensor material.

  12. Nanocellulose as a sustainable biomass material: structure, properties, present status and future prospects in biomedical applications.

    Science.gov (United States)

    Xue, Yan; Mou, Zihao; Xiao, Huining

    2017-10-12

    Nanocellulose, extracted from the most abundant biomass material cellulose, has proved to be an environmentally friendly material with excellent mechanical performance owing to its unique nano-scaled structure, and has been used in a variety of applications as engineering and functional materials. The great biocompatibility and biodegradability, in particular, render nanocellulose promising in biomedical applications. In this review, the structure, treatment technology and properties of three different nanocellulose categories, i.e., nanofibrillated cellulose (NFC), nanocrystalline cellulose (NCC) and bacterial nanocellulose (BNC), are introduced and compared. The cytotoxicity, biocompatibility and frontier applications in biomedicine of the three nanocellulose categories were the focus and are detailed in each section. Future prospects concerning the cytotoxicity, applications and industrial production of nanocellulose are also discussed in the last section.

  13. Some Tests for Evaluation of Contingency Tables (for Biomedical Applications)

    Czech Academy of Sciences Publication Activity Database

    Kalina, Jan

    2011-01-01

    Roč. 7, č. 1 (2011), s. 37-50 ISSN 1336-9180 R&D Projects: GA MŠk(CZ) 1M06014 Institutional research plan: CEZ:AV0Z10300504 Keywords : contingency tables * hypothesis testing Subject RIV: BB - Applied Statistics, Operational Research http://jamsi.fpv.ucm.sk/docs/v07n01_05_2011/v07_n01_03_KALINA.pdf

  14. A novel multifunctional biomedical material based on polyacrylonitrile: Preparation and characterization

    International Nuclear Information System (INIS)

    Wu, Huan-ling; Bremner, David H.; Li, He-yu; Shi, Qi-quan; Wu, Jun-zi; Xiao, Rui-qiu; Zhu, Li-min

    2016-01-01

    Wet spun microfibers have great potential in the design of multifunctional controlled release materials. Curcumin (Cur) and vitamin E acetate (Vit. E Ac) were used as a model drug system to evaluate the potential application of the drug-loaded microfiber system for enhanced delivery. The drugs and polyacrylonitrile (PAN) were blended together and spun to produce the target drug-loaded microfiber using an improved wet-spinning method and then the microfibers were successfully woven into fabrics. Morphological, mechanical properties, thermal behavior, drug release performance characteristics, and cytocompatibility were determined. The drug-loaded microfiber had a lobed “kidney” shape with a height of 50–100 μm and width of 100–200 μm. The addition of Cur and Vit. E Ac had a great influence on the surface and cross section structure of the microfiber, leading to a rough surface having microvoids. X-ray diffraction and Fourier transform infrared spectroscopy indicated that the drugs were successfully encapsulated and dispersed evenly in the microfilament fiber. After drug loading, the mechanical performance of the microfilament changed, with the breaking strength improved slightly, but the tensile elongation increased significantly. Thermogravimetric results showed that the drug load had no apparent adverse effect on the thermal properties of the microfibers. However, drug release from the fiber, as determined through in-vitro experiments, is relatively low and this property is maintained over time. Furthermore, in-vitro cytocompatibility testing showed that no cytotoxicity on the L929 cells was found up to 5% and 10% respectively of the theoretical drug loading content (TDLC) of curcumin and vitamin E acetate. This study provides reference data to aid the development of multifunctional textiles and to explore their use in the biomedical material field. - Highlights: • Based on a wet spinning technique, a series of filaments which can be used as biomaterial

  15. A novel multifunctional biomedical material based on polyacrylonitrile: Preparation and characterization

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Huan-ling [College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620 (China); Jiuzhou College of Pharmacy, Yancheng Institute of Industry Technology, Yancheng 224005 (China); Bremner, David H. [School of Science, Engineering and Technology, Kydd Building, Abertay University, Dundee DD1 1HG, Scotland (United Kingdom); Li, He-yu; Shi, Qi-quan; Wu, Jun-zi; Xiao, Rui-qiu [College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620 (China); Zhu, Li-min, E-mail: lzhu@dhu.edu.cn [College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620 (China)

    2016-05-01

    Wet spun microfibers have great potential in the design of multifunctional controlled release materials. Curcumin (Cur) and vitamin E acetate (Vit. E Ac) were used as a model drug system to evaluate the potential application of the drug-loaded microfiber system for enhanced delivery. The drugs and polyacrylonitrile (PAN) were blended together and spun to produce the target drug-loaded microfiber using an improved wet-spinning method and then the microfibers were successfully woven into fabrics. Morphological, mechanical properties, thermal behavior, drug release performance characteristics, and cytocompatibility were determined. The drug-loaded microfiber had a lobed “kidney” shape with a height of 50–100 μm and width of 100–200 μm. The addition of Cur and Vit. E Ac had a great influence on the surface and cross section structure of the microfiber, leading to a rough surface having microvoids. X-ray diffraction and Fourier transform infrared spectroscopy indicated that the drugs were successfully encapsulated and dispersed evenly in the microfilament fiber. After drug loading, the mechanical performance of the microfilament changed, with the breaking strength improved slightly, but the tensile elongation increased significantly. Thermogravimetric results showed that the drug load had no apparent adverse effect on the thermal properties of the microfibers. However, drug release from the fiber, as determined through in-vitro experiments, is relatively low and this property is maintained over time. Furthermore, in-vitro cytocompatibility testing showed that no cytotoxicity on the L929 cells was found up to 5% and 10% respectively of the theoretical drug loading content (TDLC) of curcumin and vitamin E acetate. This study provides reference data to aid the development of multifunctional textiles and to explore their use in the biomedical material field. - Highlights: • Based on a wet spinning technique, a series of filaments which can be used as biomaterial

  16. Railgun bore material test results

    International Nuclear Information System (INIS)

    Wang, S.Y.; Burton, R.L.; Witherspoon, F.D.; Bloomberg, H.W.; Goldstein, S.A.; Tidman, D.A.; Winsor, N.K.

    1987-01-01

    GT-Devices, Inc. has constructed a material test facility (MTF) to study the fundamental heat transfer problem of both railgun and electrothermal guns, and to test candidate gun materials under real plasma conditions. The MTF electrothermally produces gigawatt-level plasmas with pulse lengths of 10-30 microseconds. Circular bore and non-circular bore test barrels have been successfully operated under a wide range of simulated heating environments for EM launchers. Diagnostics include piezoelectric MHz pressure probes, time-of-flight probes, and current and voltage probes. Ablation measurements are accomplished by weighing and optical inspection, including borescope, optical microscope, and scanning electron microscope (SEM). From these measurements the ablation threshold for both the rail and insulator materials can be determined as a function of plasma heating. The MTF diagnostics are supported by an unsteady 1-D model of MTF which uses the flux-corrected transport (FCT) algorithm to calculate the fluid equations in conservative form. A major advantage of the FCT algorithm is that it can model gas dynamic shock behaviour without the requirement of numerical diffusion. The principle use of the code is to predict the material surface temperature ΔT/α from the unsteady heat transfer q(t)

  17. Biopolymers as materials for developing products in pharmaceutical applications and biomedical uses

    Directory of Open Access Journals (Sweden)

    Manuel Guillermo Rojas Cortés

    2008-01-01

    Full Text Available Biopolymers have been widely studied for use in pharmaceutical applications. They have been used for modifying drug release, orientating a drug towards its therapeutic target, penetrating physiological barriers (tissues and cells and protecting unstable therapeutic agents against physiological conditions which are present in a less invasive administration routes. The importance of biopolymers in designing new biomedical devices must thus be stressed, es-pecially when a pharmaceutical substance must be incorporated into a polymer matrix. A new generation of alterna-tives for human health has thus been generated by designing pharmaceutical therapeutic systems in line with the concept of “integrated custom-made product design”. This document reviews the trends concerning using biopoly-mers for designing products having pharmaceutical and biomedical applications. The paper also introduces the elements which should be mastered by engineers for obtaining material which can be used in the health field and tries to provide a reference point regarding the state of the art in this specific field of knowledge.

  18. Biomedical studies on solvent refined coal (SRC-II) liquefaction materials: a status report

    Energy Technology Data Exchange (ETDEWEB)

    1979-10-01

    This technical report summarizes the results of biomedical research effort on solvent refined coal (SRC) materials. The samples, described in the text, as well as samples of raw shale oil, crude petroleum, and some SRC-I materials were evaluated for biological activity in several different systems: (1) microbial mutagenesis (Ames assay), coupled to chemical characterization efforts, (2) in vitro mammalian cell toxicity and transformation, (3) epidermal carcinogenesis (skin painting) in mice, (4) acute and subchronic oral toxicity in rats, (5) developmental toxicity in rats, and (6) dosimetry and metabolism in rats. High boiling point materials (identified) showed significant mutagenic activity while lower boiling fractions from both processes were inactive; crude petroleum was also inactive, while raw shale oil showed only a low level of activity. Chemical characterization studies suggested that 3- and 4-ring primary aromatic amines are responsible for a large fraction of the mutagenic activity. Cultured mammalian cell studies showed that materials exhibiting a positive effect in the Ames system also caused mammalian cell transformation. The results of skin carcinogenesis studies in the mouse were generally consistent with those of the cellular studies. Light distillates were found to be moderately toxic after oral administration to rats. Fuel upgrading, process modification, and appropriate occupational/environmental controls may ameliorate some of the biological effects of SRC materials and other coal liquids of high boiling point. Low-boiling SRC liquids appear to have little biological effects in the assays employed. (LTN)

  19. Green Chemistry: Effect of Microwave Irradiationon Synthesis of Chitosan for Biomedical Grade Applications of Biodegradable Materials

    Directory of Open Access Journals (Sweden)

    Amri Setyawati

    2016-10-01

    Full Text Available Microwave assisted chitosan synthesis as biodegradable material for biomedical application has been done. The purpose of this research is to synthesis of chitosan with high DD and low molecular weight using microwave energy, the study of reaction conditions include parameters of power and reaction time. Chitosan was prepared by deacetylation of chitin with 60% NaOH solution. Conventional method has been done by reflux for 90minutes, resulting chitosan with DD of 79.5%, 72.6% yields and molecular weight 6051 g/mol. Green chemistry method using microwave radiation at 800 Watts for 5 minutes has produced chitosan with highest DD, yield and molecular weight of 86%, 75% and 3797 g/mole respectively. Synthesis of Chitosan by microwave radiation method can save 10x electrical energy for the reaction, also rapidly and effectively to produce chitosan with low molecular weight compared to conventional methods

  20. Mechanically enhanced nested-network hydrogels as a coating material for biomedical devices.

    Science.gov (United States)

    Wang, Zhengmu; Zhang, Hongbin; Chu, Axel J; Jackson, John; Lin, Karen; Lim, Chinten James; Lange, Dirk; Chiao, Mu

    2018-02-12

    Well-organized composite formations such as hierarchical nested-network (NN) structure in bone tissue and reticular connective tissue present remarkable mechanical strength and play a crucial role in achieving physical and biological functions for living organisms. Inspired by these delicate microstructures in nature, an analogous scaffold of double network hydrogel was fabricated by creating a poly(2-hydroxyethyl methacrylate) (pHEMA) network in the porous structure of alginate hydrogels. The resulting hydrogel possessed hierarchical NN structure and showed significantly improved mechanical strength but still maintained high elasticity comparable to soft tissues due to a mutual strengthening effect between the two networks. The tough hydrogel is also self-lubricated, exhibiting a surface friction coefficient comparable with polydimethylsiloxane (PDMS) substrates lubricated by a commercial aqueous lubricant (K-Y Jelly) and other low surface friction hydrogels. Additional properties of this hydrogel include high hydrophilicity, good biocompatibility, tunable cell adhesion and bacterial resistance after incorporation of silver nanoparticles. Firm bonding of the hydrogel on silicone substrates could be achieved through facile chemical modification, thus enabling the use of this hydrogel as a versatile coating material for biomedical applications. In this study, we developed a tough hydrogel by crosslinking HEMA monomers in alginate hydrogels and forming a well-organized structure of hierarchical nested network (NN). Different from most reported stretchable alginate-based hydrogels, the NN hydrogel shows higher compressive strength but retains comparable softness to alginate counterparts. This work further demonstrated the good integration of the tough hydrogel with silicone substrates through chemical modification and micropillar structures. Other properties including surface friction, biocompatibility and bacterial resistance were investigated and the hydrogel shows

  1. Nile tilapia skin collagen sponge modified with chemical cross-linkers as a biomedical hemostatic material.

    Science.gov (United States)

    Sun, Leilei; Li, Bafang; Jiang, Dandan; Hou, Hu

    2017-11-01

    Nile tilapia skin collagen sponges were fabricated by freeze-drying technology and modified with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide in the presence of N-hydroxysuccinimide (EDC/NHS), genipin+PBS, genipin+ethanol, tea polyphenol (TP), nordihydroguaiaretic acid (NDGA) and diphenyl phosphoryl azide (DPPA). Physicochemical and biological properties, micromorphology and compatibility before and after modification were investigated to evaluate collagen sponge as a hemostatic biomedical material. The mechanical property of collagen sponges strengthened after cross-linking. The elongation at break of cross-linked collagen sponges decreased except for EDC/NHS, which was close to that of non-crosslinked. The collagen sponge cross-linked with EDC/NHS exhibited the highest hygroscopicity in comparison with other cross-linkers. The resistance to collagenase biodegradation of collagen sponges after cross-linking strengthened significantly except for NDGA. Collagen sponges cross-linked with EDC/NHS, TP and NDGA maintained high porosity (97-98%), similar to non-crosslinked (98.42%). Collagen sponges could shorten the blood coagulation time. From the variations of the FTIR spectrum pattern and SEM, DPPA could change the secondary structure of collagen and destroy the spongy structure of collagen sponge, which was not suitable for the cross-linking of collagen sponge. Whereas, EDC/NHS was recognized as a perfect cross-linker owing to its excellent properties and porous microstructure. All fabricated collagen sponges were recognized to be biocompatible by the hemolysis assay in vitro. Therefore, collagen sponge modified with EDC/NHS could be used as a perfect biomedical hemostatic material. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Biomedical engineering and nanotechnology

    International Nuclear Information System (INIS)

    Pawar, S.H.; Khyalappa, R.J.; Yakhmi, J.V.

    2009-01-01

    This book is predominantly a compilation of papers presented in the conference which is focused on the development in biomedical materials, biomedical devises and instrumentation, biomedical effects of electromagnetic radiation, electrotherapy, radiotherapy, biosensors, biotechnology, bioengineering, tissue engineering, clinical engineering and surgical planning, medical imaging, hospital system management, biomedical education, biomedical industry and society, bioinformatics, structured nanomaterial for biomedical application, nano-composites, nano-medicine, synthesis of nanomaterial, nano science and technology development. The papers presented herein contain the scientific substance to suffice the academic directivity of the researchers from the field of biomedicine, biomedical engineering, material science and nanotechnology. Papers relevant to INIS are indexed separately

  3. Repetitively pulsed material testing facility

    International Nuclear Information System (INIS)

    Zucker, O.; Bostick, W.; Gullickson, R.; Long, J.; Luce, J.; Sahlin, H.

    1975-01-01

    A continuously operated, 1 pps, dense-plasma-focus device capable of delivering a minimum of 10 15 neutrons per pulse for material testing purposes is described. Moderate scaling from existing results is sufficient to provide 2 x 10 13 n/cm 2 . s to a suitable target. The average power consumption, which has become a major issue as a result of the energy crisis, is analyzed with respect to other plasma devices and is shown to be highly favorable. A novel approach to the capacitor bank and switch design allowing repetitive operation is discussed

  4. Repetitively pulsed material testing facility

    International Nuclear Information System (INIS)

    Zucker, O.; Bostick, W.; Gullickson, R; Long, J.; Luce, J.; Sahlin, H.

    1975-01-01

    A continuously operated, 1 pps, dense-plasma-focus device capable of delivering a minimum of 10 15 neutrons per pulse for material testing purposes is described. Moderate scaling from existing results is sufficient to provide 2 x 10 13 n/cm 2 .s to a suitable target. The average power consumption, which has become a major issue as a result of the energy crisis, is analyzed with respect to other plasma devices and is shown to be highly favorable. A novel approach to the capacitor bank and switch design allowing repetitive operation is discussed. (U.S.)

  5. Fusion Materials Irradiation Test Facility

    International Nuclear Information System (INIS)

    Kemp, E.L.; Trego, A.L.

    1979-01-01

    A Fusion Materials Irradiation Test Facility is being designed to be constructed at Hanford, Washington, The system is designed to produce about 10 15 n/cm-s in a volume of approx. 10 cc and 10 14 n/cm-s in a volume of 500 cc. The lithium and target systems are being developed and designed by HEDL while the 35-MeV, 100-mA cw accelerator is being designed by LASL. The accelerator components will be fabricated by US industry. The total estimated cost of the FMIT is $105 million. The facility is scheduled to begin operation in September 1984

  6. A Short Overview on the Biomedical Applications of Silica, Alumina and Calcium Phosphate-based Nanostructured Materials.

    Science.gov (United States)

    Ellahioui, Younes; Prashar, Sanjiv; Gómez-Ruiz, Santiago

    2016-01-01

    This article reviews the use of silica, alumina and calcium phosphate-based nanostructured materials with biomedical applications. A short introduction on the use of the materials in Science, Nanotechnology and Health is included followed by a revision of each of the selected materials. A description of the principal synthetic methods used in the preparation of the materials in nanostructured form is included. The most widely used applications in biomedicine are reviewed including, for example drug-delivery, bone regeneration, imaging, sensoring amongst others. Finally, a short description of the toxicity and cytotoxicity associated with each of the materials of this revision is presented. This short literature revision serves to demonstrate the very promising future ahead of nanosystems based on silica, alumina and calcium phosphate for biological and biomedical applications.

  7. Titanium coated with functionalized carbon nanotubes — A promising novel material for biomedical application as an implantable orthopaedic electronic device

    Energy Technology Data Exchange (ETDEWEB)

    Przekora, Agata, E-mail: agata.przekora@umlub.pl [Department of Biochemistry and Biotechnology, Medical University of Lublin, Faculty of Pharmacy with Medical Analytics Division, Chodzki 1, 20-093 Lublin (Poland); Benko, Aleksandra; Nocun, Marek; Wyrwa, Jan; Blazewicz, Marta [Faculty of Materials Science and Ceramics, AGH-Univ. of Science and Technology, A. Mickiewicz 30 Ave., 30-059 Cracow (Poland); Ginalska, Grazyna [Department of Biochemistry and Biotechnology, Medical University of Lublin, Faculty of Pharmacy with Medical Analytics Division, Chodzki 1, 20-093 Lublin (Poland)

    2014-12-01

    The aim of the study was to fabricate titanium (Ti) material coated with functionalized carbon nanotubes (f-CNTs) that would have potential medical application in orthopaedics as an implantable electronic device. The novel biomedical material (Ti-CNTs-H{sub 2}O) would possess specific set of properties, such as: electrical conductivity, non-toxicity, and ability to inhibit connective tissue cell growth and proliferation protecting the Ti-CNTs-H{sub 2}O surface against covering by cells. The novel material was obtained via an electrophoretic deposition of CNTs-H{sub 2}O on the Ti surface. Then, physicochemical, electrical, and biological properties were evaluated. Electrical property evaluation revealed that a Ti-CNTs-H{sub 2}O material is highly conductive and X-ray photoelectron spectroscopy analysis demonstrated that there are mainly COOH groups on the Ti-CNTs-H{sub 2}O surface that are found to inhibit cell growth. Biological properties were assessed using normal human foetal osteoblast cell line (hFOB 1.19). Conducted cytotoxicity tests and live/dead fluorescent staining demonstrated that Ti-CNTs-H{sub 2}O does not exert toxic effect on hFOB cells. Moreover, fluorescence laser scanning microscope observation demonstrated that Ti-CNTs-H{sub 2}O surface retards to a great extent cell proliferation. The study resulted in successful fabrication of highly conductive, non-toxic Ti-CNTs-H{sub 2}O material that possesses ability to inhibit osteoblast proliferation and thus has a great potential as an orthopaedic implantable electronic device. - Highlights: • Functionalized carbon nanotubes were electrophoretically deposited on Ti surface. • Physicochemical, electrical, and biological properties were evaluated. • Ti-CNTs-H{sub 2}O is highly conductive and there are mainly COOH groups on its surface. • Novel material is non-toxic and retards to a great extent osteoblast proliferation. • Ti-CNTs-H{sub 2}O has a promising potential as implantable orthopaedic

  8. Ruggedising biomedical devices for field-testing in resource-constrained environments: Context, issues and solutions

    Directory of Open Access Journals (Sweden)

    Sarah Schopman

    2013-08-01

    Full Text Available Community Health Workers (CHWs are community members who address primary health challenges through education, prevention, and awareness initiatives. CHWs conduct home visits, provide treatment for simple common illnesses, and offer health education on numerous topics including nutrition, child health, and family planning. Since they serve on the frontlines of healthcare in rural communities, ruggedised and low-cost biomedical devices could improve the efficiency and efficacy of their caregiving efforts. However, the vast majority of biomedical devices used in sub-Saharan Africa are designed by engineers in Western countries who are not familiar with the distinct physical, environmental, socio-cultural, and economic environment of the context for which they are designing. Systemic challenges include long distances, poor transportation, unreliable infrastructure, harsh climate, and limited operator education. Specifically, three sets of hurdles to the adoption, sustainability and usability of devices by the CHWs include vibrations and wire strain, dust and water penetration, and device usability. This article discusses the operational context of CHWs and then delves into the specific problems encountered, and practical solutions applied, during four years of field-testing ruggedised biomedical devices in rural Kenya.

  9. Testing of Alternative Materials for Advanced Suit Bladders

    Science.gov (United States)

    Bue, Grant; Orndoff, Evelyne; Makinen, Janice; Tang, Henry

    2011-01-01

    Several candidate advanced pressure bladder membrane materials have been developed for NASA Johnson Space Center by DSM Biomedical for selective permeability of carbon dioxide and water vapor. These materials were elasthane and two other formulations of thermoplastic polyether polyurethane. Each material was tested in two thicknesses for permeability to carbon dioxide, oxygen and water vapor. Although oxygen leaks through the suit bladder would amount to only about 60 cc/hr in a full size suit, significant amounts of carbon dioxide would not be rejected by the system to justify its use. While the ratio of carbon dioxide to oxygen permeability is about 48 to 1, this is offset by the small partial pressure of carbon dioxide in acceptable breathing atmospheres of the suit. Humidity management remains a possible use of the membranes depending on the degree to which the water permeability is inhibited by cations in the sweat. Tests are underway to explore cation fouling from sweat.

  10. Test Bed for Superconducting Materials

    CERN Document Server

    Nantista, C D; Dolgashev, Valery A; Siemann, Robert; Tantawi, Sami G; Weisend, John

    2005-01-01

    Superconducting rf cavities are increasingly used in accelerators. Gradient is a parameter of particular importance for the ILC. Much progress in gradient has been made over the past decade, overcoming problems of multipacting, field emission, and breakdown triggered by surface impurities. However, the quenching limit of the surface magnetic field for niobium remains a hard limitation on cavity fields sustainable with this technology. Further exploration of materials and preparation may offer a path to surpassing the current limit. For this purpose, we have designed a resonant test cavity. One wall of the cavity is formed by a flat sample of superconducting material; the rest of the cavity is copper or niobium. The H field on the sample wall is 74% higher than on any other surface. Multipacting is avoided by use of a mode with no surface electric field. The cavity will be resonated through a coupling iris with high-power rf at superconducting temperature until the sample wall quenches, as detected by a change...

  11. Novel functionalized polymeric fabric and fiber material as solid support for solid-phase synthesis and biomedical applications

    Science.gov (United States)

    Xiang, Bei

    The aim of the research is to develop novel polymer solid support by modifying or fabricating polymeric fibrous materials for peptide synthesis and biomedical applications. Originally chemical inert isotactic polypropylene (iPP) fabric was utilized and modified to serve as a functional flexible planar solid support for solid phase peptide synthesis. The modification was achieved through thermal initiated radical grafting polymerization using acrylic acid, poly (ethylene glycol) diacrylate as monomers, and benzoyl peroxide as radical initiator. The iPP fabric was successfully functionalized and possessing as high as 0.7mmol/g carboxylic acid groups. Peptide ligand LHPQF was successfully synthesized on the new functional planar support. Specific enzyme immobilization was fulfilled on the functional iPP fabric support. A commercially available ethylene-acrylic acid copolymer was made into ultrafine copolymer fiber bundles which are composed of nanofibers with diameters ranging from 200nm to 800nm. Various mixing ratios of copolymer/matrix materials were utilized to explore the effect on the final nanofiber physical properties including morphology and stability in solvents. The surface carboxylic acid groups were further converted to amino groups before the functional nanofibers can be applied in solid phase peptide synthesis. Two peptide ligands, LHPQF and HWRGWV, were also successfully synthesized on the nanofiber bundles. Streptavidin and human immunoglobulin G specific binding with the corresponding ligand which was anchored on the nanofibers was conducted successfully to illustrate the potential applications of the nanofiber materials in biomedical field. Further study on the dispersion of the ethylene-acrylic acid nanofiber bundles was pursued to take advantage of the super high active surface area of functional nanofibers. To manipulate the polymer nanofibers during synthesis and bio-assays, a technique was developed to controllably assemble and disperse the

  12. Titanium coated with functionalized carbon nanotubes--a promising novel material for biomedical application as an implantable orthopaedic electronic device.

    Science.gov (United States)

    Przekora, Agata; Benko, Aleksandra; Nocun, Marek; Wyrwa, Jan; Blazewicz, Marta; Ginalska, Grazyna

    2014-12-01

    The aim of the study was to fabricate titanium (Ti) material coated with functionalized carbon nanotubes (f-CNTs) that would have potential medical application in orthopaedics as an implantable electronic device. The novel biomedical material (Ti-CNTs-H2O) would possess specific set of properties, such as: electrical conductivity, non-toxicity, and ability to inhibit connective tissue cell growth and proliferation protecting the Ti-CNTs-H2O surface against covering by cells. The novel material was obtained via an electrophoretic deposition of CNTs-H2O on the Ti surface. Then, physicochemical, electrical, and biological properties were evaluated. Electrical property evaluation revealed that a Ti-CNTs-H2O material is highly conductive and X-ray photoelectron spectroscopy analysis demonstrated that there are mainly COOH groups on the Ti-CNTs-H2O surface that are found to inhibit cell growth. Biological properties were assessed using normal human foetal osteoblast cell line (hFOB 1.19). Conducted cytotoxicity tests and live/dead fluorescent staining demonstrated that Ti-CNTs-H2O does not exert toxic effect on hFOB cells. Moreover, fluorescence laser scanning microscope observation demonstrated that Ti-CNTs-H2O surface retards to a great extent cell proliferation. The study resulted in successful fabrication of highly conductive, non-toxic Ti-CNTs-H2O material that possesses ability to inhibit osteoblast proliferation and thus has a great potential as an orthopaedic implantable electronic device. Copyright © 2014 Elsevier B.V. All rights reserved.

  13. Column Selection for Biomedical Analysis Supported by Column Classification Based on Four Test Parameters.

    Science.gov (United States)

    Plenis, Alina; Rekowska, Natalia; Bączek, Tomasz

    2016-01-21

    This article focuses on correlating the column classification obtained from the method created at the Katholieke Universiteit Leuven (KUL), with the chromatographic resolution attained in biomedical separation. In the KUL system, each column is described with four parameters, which enables estimation of the FKUL value characterising similarity of those parameters to the selected reference stationary phase. Thus, a ranking list based on the FKUL value can be calculated for the chosen reference column, then correlated with the results of the column performance test. In this study, the column performance test was based on analysis of moclobemide and its two metabolites in human plasma by liquid chromatography (LC), using 18 columns. The comparative study was performed using traditional correlation of the FKUL values with the retention parameters of the analytes describing the column performance test. In order to deepen the comparative assessment of both data sets, factor analysis (FA) was also used. The obtained results indicated that the stationary phase classes, closely related according to the KUL method, yielded comparable separation for the target substances. Therefore, the column ranking system based on the FKUL-values could be considered supportive in the choice of the appropriate column for biomedical analysis.

  14. A novel combined polyphenol-aldehyde crosslinking of collagen film-Applications in biomedical materials.

    Science.gov (United States)

    Liu, Ting; Shi, Lu; Gu, Zhipeng; Dan, Weihua; Dan, Nianhua

    2017-08-01

    Despite its crucial role in directing cell fate in healthy and diseased tissues, improvements in physical-chemical properties and biocompatibility of type-I collagen are still needed. In this report, we described combined and facile method to modify collagen. The collagen film was first modified by procyanidins solution, in which, then subjected to further crosslinked by dialdehyde alginate, resulting in collagen-procyanidins-dialdehyde alginate film. The properties of the crosslinked collagen films were investigated and the results were discussed. Results from differential scanning calorimetry and thermo gravimetric analysis suggested that the thermal stabilities of the collagen-procyanidins-dialdehyde alginate film were significantly improved. The mechanical properties of collagen-procyanidins-dialdehyde alginate film in terms of elongation at break and tensile strength increased approximately 2-fold and 3-fold, respectively compare to pure collagen film. In addition, the resistance to collagenase degradation of collagen-procyanidins-dialdehyde alginate film was remarkably promoted. The results from methyltetrazolium assay and confocal laser scanning microscopy showed that no cytotoxicity of collagen film was introduced by the combined crosslinking method. Thus, the novel combined by procyanidins-dialdehyde alginate crosslinking method shown in this study provided a non-toxic and efficient crosslinking method that improved various properties of collagen film, which has great potential applications in biomedical materials. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Thermal Systems and Materials Testing

    Science.gov (United States)

    Aguirre, Nathan

    2010-01-01

    During my internship, I was involved in Boeing Thermal System/M&P, which handles maintenance and repairs of shuttle tiles, blankets, gap fillers, etc. One project I took part in was the revision of TPS-227, a repair process to tiles that entailed drilling out tile damage and using a cylindrical insert to fill the hole. The previous specification used minimal adhesive for application and when the adhesive cured, there would be several voids in the adhered material, causing an unsatisfactory bond. The testing compared several new methods and I analyzed the number of voids produced by each method to determine which one was most effective at eliminating void space. We revised the original process to apply a light adhesive coat to the top 25% of the borehole and a heavy coat to 100% of the insert. I was also responsible for maintaining the subnominal bond database, which records all unsatisfactory SIP (Strain Isolator Pad) bonds. I then archived each SIP physically for future referral data and statistics. In addition, I performed post-flight tile inspections for damages and wrote dispositions to have these tiles repaired. This also included writing a post-flight damage report for a section of Atlantis and creating summarized repair process guidelines for orbiter technicians.

  16. Experimental Testing of the New Biomedical Substance of Pig Kidneys for the Treatment of Nephrolithiasis

    Directory of Open Access Journals (Sweden)

    Aleksandr Yu. Zharikov

    2017-03-01

    Full Text Available The aim of our study was to test anti-lithogenic activity of the new biomedical substance from pig kidneys (PK-BMS on the experimentally induced nephrolithiasis. Materials and Methods: The experiments were performed with 30 male Wistar outbred rats weighting 220g-280g. The experimental animals were divided into two groups. In the disease-control group (DCG, the animals received a 1% solution of EG for 6 weeks. The rats in therapy group (TG, beginning from the fourth week, in addition to the daily EG intake, received PK-BMS in the amount of 1.0 per rat. The production of this substance was carried out at Altaivitaminy ZAO (Biysk, Altai Krai, Russia by the method of cool dehumidification. In daily urine, we determined the concentration of oxalate, phosphate and calcium ions, creatinine excretion every 3 or 4 days in both groups; the activity of LDH, GGT, and NAG was measured every 7 days in the injured kidney epithelium. For the study of free-radical oxidation activity and for morphological examination of animal kidneys, after 6 weeks of the experiment, 5 rats from each group were euthanized. The occurrence of calcium compounds was determined by von Kossa’s staining method. Results: After a 6-week EG intake, we found the typical biochemical and morphological symptoms of experimental nephrolithiasis in rats of DCG: urine supersaturation with oxalate ions, significant increase in the activity of marker enzymes, activation of free-radical oxidation in the kidneys, and formation of calcium deposits in the kidneys. In TG, the new PK-BMS intake resulted in a significant alleviation of the experimental nephrolithiasi: significant decrease in the level of oxalate ions and activity of marker enzymes, reduction of free-radical oxidation in the kidneys, decrease in the number and size of calcium deposits in the area of renal papillae. Conclusion: It was established that during the experimental nephrolithiasis, a three-week intake of the new PK-BMS is

  17. Microstructure and mechanical behavior of metal injection molded Ti-Nb binary alloys as biomedical material.

    Science.gov (United States)

    Zhao, Dapeng; Chang, Keke; Ebel, Thomas; Qian, Ma; Willumeit, Regine; Yan, Ming; Pyczak, Florian

    2013-12-01

    The application of titanium (Ti) based biomedical materials which are widely used at present, such as commercially pure titanium (CP-Ti) and Ti-6Al-4V, are limited by the mismatch of Young's modulus between the implant and the bones, the high costs of products, and the difficulty of producing complex shapes of materials by conventional methods. Niobium (Nb) is a non-toxic element with strong β stabilizing effect in Ti alloys, which makes Ti-Nb based alloys attractive for implant application. Metal injection molding (MIM) is a cost-efficient near-net shape process. Thus, it attracts growing interest for the processing of Ti and Ti alloys as biomaterial. In this investigation, metal injection molding was applied to the fabrication of a series of Ti-Nb binary alloys with niobium content ranging from 10wt% to 22wt%, and CP-Ti for comparison. Specimens were characterized by melt extraction, optical microscopy, X-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive spectroscopy (EDS), and transmission electron microscopy (TEM). Titanium carbide formation was observed in all the as-sintered Ti-Nb binary alloys but not in the as-sintered CP-Ti. Selected area electron diffraction (SAED) patterns revealed that the carbides are Ti2C. It was found that with increasing niobium content from 0% to 22%, the porosity increased from about 1.6% to 5.8%, and the carbide area fraction increased from 0% to about 1.8% in the as-sintered samples. The effects of niobium content, porosity and titanium carbides on mechanical properties have been discussed. The as-sintered Ti-Nb specimens exhibited an excellent combination of high tensile strength and low Young's modulus, but relatively low ductility. © 2013 Elsevier Ltd. All rights reserved.

  18. Tribological Tuft Testing Candidate Brush Seal Materials

    Science.gov (United States)

    DellaCorte, Chris

    1999-01-01

    This paper presents a tribological tuft test method of candidate brush seal materials in viewgraph form. The goals of the research are: 1) To develop test method to tribologically brush seal materials; 2) To evaluate materials to identify potential improvements and trends; and 3) Guide seal material development and selection.

  19. 46 CFR 154.430 - Material test.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Material test. 154.430 Section 154.430 Shipping COAST... § 154.430 Material test. (a) The membrane and the membrane supporting insulation must be made of materials that withstand the combined strains calculated under § 154.429(c). (b) Analyzed data of a material...

  20. Reference materials and representative test materials: the nanotechnology case

    Energy Technology Data Exchange (ETDEWEB)

    Roebben, G., E-mail: gert.roebben@ec.europa.eu [Joint Research Centre of the European Commission, Institute for Reference Materials and Measurements (Belgium); Rasmussen, K. [Joint Research Centre of the European Commission, Institute for Health and Consumer Protection (Italy); Kestens, V.; Linsinger, T. P. J. [Joint Research Centre of the European Commission, Institute for Reference Materials and Measurements (Belgium); Rauscher, H. [Joint Research Centre of the European Commission, Institute for Health and Consumer Protection (Italy); Emons, H. [Joint Research Centre of the European Commission, Institute for Reference Materials and Measurements (Belgium); Stamm, H. [Joint Research Centre of the European Commission, Institute for Health and Consumer Protection (Italy)

    2013-03-15

    An increasing number of chemical, physical and biological tests are performed on manufactured nanomaterials for scientific and regulatory purposes. Existing test guidelines and measurement methods are not always directly applicable to or relevant for nanomaterials. Therefore, it is necessary to verify the use of the existing methods with nanomaterials, thereby identifying where modifications are needed, and where new methods need to be developed and validated. Efforts for verification, development and validation of methods as well as quality assurance of (routine) test results significantly benefit from the availability of suitable test and reference materials. This paper provides an overview of the existing types of reference materials and introduces a new class of test materials for which the term 'representative test material' is proposed. The three generic concepts of certified reference material, reference material(non-certified) and representative test material constitute a comprehensive system of benchmarks that can be used by all measurement and testing communities, regardless of their specific discipline. This paper illustrates this system with examples from the field of nanomaterials, including reference materials and representative test materials developed at the European Commission's Joint Research Centre, in particular at the Institute for Reference Materials and Measurements (IRMM), and at the Institute for Health and Consumer Protection (IHCP).

  1. Critical evaluation of the use of dogs in biomedical research and testing in Europe.

    Science.gov (United States)

    Hasiwa, Nina; Bailey, Jarrod; Clausing, Peter; Daneshian, Mardas; Eileraas, Marianne; Farkas, Sándor; Gyertyán, István; Hubrecht, Robert; Kobel, Werner; Krummenacher, Goran; Leist, Marcel; Lohi, Hannes; Miklósi, Adám; Ohl, Frauke; Olejniczak, Klaus; Schmitt, Georg; Sinnett-Smith, Patrick; Smith, David; Wagner, Kristina; Yager, James D; Zurlo, Joanne; Hartung, Thomas

    2011-01-01

    Dogs are sometimes referred to as "man's best friend" and with the increase in urbanization and lifestyle changes, dogs are seen by their owners as family members. Society expresses specific concerns about the experimental use of dogs, as they are sometimes perceived to have a special status for humans. This may appear somewhat conflicting with the idea that the intrinsic value of all animals is the same, and that also several other animal species are used in biomedical research and toxicology. This aspect and many others are discussed in an introductory chapter dealing with ethical considerations on the use of dogs as laboratory animals. The report gives an overview on the use of dogs in biomedical research, safety assessment and the drug developmental process and reflects the discussion on the use of dogs as second (non-rodent)species in toxicity testing. Approximately 20,000 dogs are used in scientific procedures in Europe every year, and their distinct genetic, physiological and behavioral characteristics may support their use as models for e.g. behavioral analysis and genetic research. Advances in the 3Rs (Replacement, Reduction and Refinement of experiments using dogs) are described, potential opportunities are discussed and recommendations for further progress in this area are made.

  2. Nondestructive ultrasonic testing of materials

    Science.gov (United States)

    Hildebrand, B.P.

    1994-08-02

    Reflection wave forms obtained from aged and unaged material samples can be compared in order to indicate trends toward age-related flaws. Statistical comparison of a large number of data points from such wave forms can indicate changes in the microstructure of the material due to aging. The process is useful for predicting when flaws may occur in structural elements of high risk structures such as nuclear power plants, airplanes, and bridges. 4 figs.

  3. Methods of evaluating protective clothing relative to heat and cold stress: thermal manikin, biomedical modeling, and human testing.

    Science.gov (United States)

    O'Brien, Catherine; Blanchard, Laurie A; Cadarette, Bruce S; Endrusick, Thomas L; Xu, Xiaojiang; Berglund, Larry G; Sawka, Michael N; Hoyt, Reed W

    2011-10-01

    Personal protective equipment (PPE) refers to clothing and equipment designed to protect individuals from chemical, biological, radiological, nuclear, and explosive hazards. The materials used to provide this protection may exacerbate thermal strain by limiting heat and water vapor transfer. Any new PPE must therefore be evaluated to ensure that it poses no greater thermal strain than the current standard for the same level of hazard protection. This review describes how such evaluations are typically conducted. Comprehensive evaluation of PPE begins with a biophysical assessment of materials using a guarded hot plate to determine the thermal characteristics (thermal resistance and water vapor permeability). These characteristics are then evaluated on a thermal manikin wearing the PPE, since thermal properties may change once the materials have been constructed into a garment. These data may be used in biomedical models to predict thermal strain under a variety of environmental and work conditions. When the biophysical data indicate that the evaporative resistance (ratio of permeability to insulation) is significantly better than the current standard, the PPE is evaluated through human testing in controlled laboratory conditions appropriate for the conditions under which the PPE would be used if fielded. Data from each phase of PPE evaluation are used in predictive models to determine user guidelines, such as maximal work time, work/rest cycles, and fluid intake requirements. By considering thermal stress early in the development process, health hazards related to temperature extremes can be mitigated while maintaining or improving the effectiveness of the PPE for protection from external hazards.

  4. Environmental testing techniques for electronics and materials

    CERN Document Server

    Dummer, Geoffrey W A; Fry, D W; Higinbotham, W

    2013-01-01

    Environmental Testing Techniques for Electronics and Materials reviews environmental testing techniques for evaluating the performance of electronic equipment, components, and materials. Environmental test planning, test methods, and instrumentation are described, along with the general environmental conditions under which equipment must operate. This book is comprised of 15 chapters and begins by explaining why environmental testing is necessary and describing the environment in which electronics must operate. The next chapter considers how an environmental test plan is designed; the methods

  5. Material characterization models and test methods for historic building materials

    DEFF Research Database (Denmark)

    Hansen, Tessa Kvist; Peuhkuri, Ruut Hannele; Møller, Eva B.

    2017-01-01

    Predictions of long term hygrothermal performance can be assessed by dynamic hygrothermal simulations, in which material parameters are crucial input. Material parameters for especially historic materials are often unknown; therefore, there is a need to determine important parameters, and simple...... decisive parameters through simple testing of interrelated parameters that are easier to determine....

  6. HFR irradiation testing of fusion materials

    International Nuclear Information System (INIS)

    Conrad, R.; von der Hardt, P.; Loelgen, R.; Scheurer, H.; Zeisser, P.

    1984-01-01

    The present and future role of the High Flux Reactor Petten for fusion materials testing has been assessed. For practical purposes the Tokamak-based fusion reactor is chosen as a point of departure to identify material problems and materials data needs. The identification is largely based on the INTOR and NET design studies, the reported programme strategies of Japan, the U.S.A. and the European Communities for technical development of thermonuclear fusion reactors and on interviews with several experts. Existing and planned irradiation facilities, their capabilities and limitations concerning materials testing have been surveyed and discussed. It is concluded that fission reactors can supply important contributions for fusion materials testing. From the point of view of future availability of fission testing reactors and their performance it appears that the HFR is a useful tool for materials testing for a large variety of materials. Prospects and recommendations for future developments are given

  7. Nanowear Testing of Composite Materials

    Czech Academy of Sciences Publication Activity Database

    Sedláček, R.; Suchý, Tomáš; Šepitka, J.; Lukeš, J.; Sochor, M.; Balík, Karel; Sucharda, Zbyněk; Beneš, J.

    2012-01-01

    Roč. 106, S3 (2012), s.519-s520 ISSN 0009-2770. [Local Mechanical Properties 2011. Olomouc, 09.11.2011-11.11.2011] R&D Projects: GA ČR(CZ) GAP108/10/1457 Institutional research plan: CEZ:AV0Z30460519 Keywords : nanoindentation * wear * mechanical properties Subject RIV: JI - Composite Materials Impact factor: 0.453, year: 2012 http://www.chemicke-listy.cz/docs/full/2012_s3_s495-s522.pdf

  8. 3D Nanostructured materials: TiO2 nanoparticles incorporated gellan gum scaffold for photocatalyst and biomedical Applications

    Science.gov (United States)

    Hasmizam Razali, Mohd; Arifah Ismail, Nur; Zulkafli, Mohd Farhan Azly Mohd; Anuar Mat Amin, Khairul

    2018-03-01

    A unique three-dimensional (3D) nanostructured gellan gum (GG) is fabricated by incorporating TiO2 nanoparticles (GG + TiO2NPs) scaffold by freeze-drying. The fabricated GG + TiO2NPs were characterized using Fourier transform infrared (FTIR), x-ray diffraction (XRD), and scanning electron microscopy (SEM) to study their physiochemical properties. FTIR was used to investigate the intermolecular interactions in the scaffolds. The crystal structure was determined by bulk analysis using XRD and SEM for microstructure observation of scaffold surfaces. The performance of synthesized GG + TiO2NPs scaffold 3D nanostructured materials was evaluated as a photocatalyst for methyl orange (MO) degradation and for biomedical applications. The results showed that the scaffold possessed good photocatalytic activity for removal of methyl orange with 88.24% degradation after 3 h of UV irradiation. The scaffold also induces the cell growth, thus offering a good candidate for biomedical applications.

  9. Thermal testing of solid neutron shielding materials

    International Nuclear Information System (INIS)

    Boonstra, R.H.

    1990-03-01

    The GA-4 and GA-9 spent fuel shipping casks employ a solid neutron shielding material. During a hypothetical thermal accident, any combustion of the neutron shield must not compromise the ability of the cask to contain the radioactive contents. A two-phase thermal testing program was carried out to assist in selecting satisfactory shielding materials. In the first phase, small-scale screening tests were performed on nine candidate materials using ASTM procedures. From these initial results, three of the nine candidates were chosen for inclusion in the second phase of testing, These materials were Bisco Products NS-4-FR, Reactor Experiments 201-1, and Reactor Experiments 207. In the second phase, each selected material was fabricated into a test article which simulated a full-scale of neutron shield from the cask. The test article was heated in an environmental prescribed by NRC regulations. Results of this second testing phase showed that all three materials are thermally acceptable

  10. Thermal testing of solid neutron shielding materials

    International Nuclear Information System (INIS)

    Boonstra, R.N.

    1990-01-01

    The GA-4 and GA-9 spent fuel shipping casks employ a solid neutron shielding material. During a hypothetical thermal accident, any combustion of the neutron shield must not compromise the ability of the cask to contain the radioactive contents. A two-phase thermal testing program was carried out to assist in selecting satisfactory shielding materials. In the first phase, small-scale screening tests were performed on nine candidate materials using ASTM procedures. From these initial results, three of the nine candidates were chosen for inclusion in the second phase of testing. These materials were Bisco Products NS-4-FR, Reactor Experiments 201-1, and Reactor Experiments 207. In the second phase, each selected material was fabricated into a test article which simulated a full-scale section of neutron shield from the cask. The test article was heated in an environment prescribed by NRC regulations. Results of this second testing phase show that all three materials are thermally acceptable

  11. Biomedical engineering fundamentals

    CERN Document Server

    Bronzino, Joseph D

    2014-01-01

    Known as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering.Biomedical Engineering Fundamentals, the first volume of the handbook, presents material from respected scientists with diverse backgrounds in physiological systems, biomechanics, biomaterials, bioelectric phenomena, and neuroengineering. More than three dozen specific topics are examined, including cardia

  12. Characterization of Powder Metallurgy Processed Pure Magnesium Materials for Biomedical Applications

    Czech Academy of Sciences Publication Activity Database

    Březina, M.; Minda, J.; Doležal, P.; Krystýnová, M.; Fintová, Stanislava; Zapletal, J.; Wasserbauer, J.; Ptáček, P.

    2017-01-01

    Roč. 7, č. 11 (2017), č. článku 461. ISSN 2075-4701 Institutional support: RVO:68081723 Keywords : magnesium * powder metallurgy * cold pressing * hot pressing * EIS (Electrochemical impedance spectroscopy) * three-point bending test * corrosion Subject RIV: JK - Corrosion ; Surface Treatment of Materials OBOR OECD: Coating and films Impact factor: 1.984, year: 2016 http://www.mdpi.com/2075-4701/7/11/461

  13. Thermal testing of solid neutron shielding materials

    International Nuclear Information System (INIS)

    Boonstra, R.H.

    1993-01-01

    In May-June 1989 the first series of full-scale thermal tests was performed on three shielding materials: Bisco Products NS-4-FR, and Reactor Experiments RX-201 and RX-207. The tests are described in Thermal Testing of Solid Neutron Shielding Materials, GA-A19897, R.H. Boonstra, General Atomics (1990), and demonstrated the acceptability of these materials in a thermal accident. Subsequent design changes to the cask rendered these materials unattractive in terms of weight or adequate service temperature margin. For the second test series a material specification was developed for a polypropylene based neutron shield with a softening point of at least 280degF. Table 1 lists the neutron shield materials tested. The Envirotech and Bisco materials are not polypropylene, but were tested as potential backup materials in the event that a satisfactory polypropylene could not be found. The Bisco modified NS-4 and Reactor Experiments HMPP are both acceptable materials from a thermal accident standpoint for use in the shipping cask. Tests of the Kobe PP-R01 and Envirotech HDPE were stopped for safety reasons, due to inability to deal with the heavy smoke, before completion of the 30-minute heating phase. However these materials may prove satisfactory if they could undergo the complete heating. (J.P.N.)

  14. Functionalized carbon nanotubes: biomedical applications

    Science.gov (United States)

    Vardharajula, Sandhya; Ali, Sk Z; Tiwari, Pooja M; Eroğlu, Erdal; Vig, Komal; Dennis, Vida A; Singh, Shree R

    2012-01-01

    Carbon nanotubes (CNTs) are emerging as novel nanomaterials for various biomedical applications. CNTs can be used to deliver a variety of therapeutic agents, including biomolecules, to the target disease sites. In addition, their unparalleled optical and electrical properties make them excellent candidates for bioimaging and other biomedical applications. However, the high cytotoxicity of CNTs limits their use in humans and many biological systems. The biocompatibility and low cytotoxicity of CNTs are attributed to size, dose, duration, testing systems, and surface functionalization. The functionalization of CNTs improves their solubility and biocompatibility and alters their cellular interaction pathways, resulting in much-reduced cytotoxic effects. Functionalized CNTs are promising novel materials for a variety of biomedical applications. These potential applications are particularly enhanced by their ability to penetrate biological membranes with relatively low cytotoxicity. This review is directed towards the overview of CNTs and their functionalization for biomedical applications with minimal cytotoxicity. PMID:23091380

  15. Quick test for percent of deleterious material.

    Science.gov (United States)

    2009-08-28

    The Missouri Department of Transportation (MoDOT) is considering the replacement of its deleterious : materials test method (TM-71) with test methods that are more objective. MoDOT contracted with the Missouri : University of Science and Technology (...

  16. Functional Materials Based on Surface Modification of Carbon Nanotubes for Biomedical and Environmental Applications

    KAUST Repository

    Mashat, Afnan

    2015-05-01

    Since the discovery of carbon nanotubes (CNTs), they have gained much interest in many science and engineering fields. The modification of CNTs by introducing different functional groups to their surface is important for CNTs to be tailored to fit the need of specific applications. This dissertation presents several CNT-based systems that can provide biomedical and environmental advantages. In this research, polyethylenimine (PEI) and polyvinyl alcohol (PVA) were used to coat CNTs through hydrogen bonding. The release of doxorubicin (DOX, an anticancer drug) from this system was controlled by temperature. This system represents a promising method for incorporating stimuli triggered polymer-gated CNTs in controlled release applications. To create an acid responsive system CNTs were coated with 1,2-Distearoyl-snglycero- 3-Phosphoethanolamine-N-[Amino(Polyethylene glycol)2000]-(PE-PEG) and Poly(acrylic acid) modified dioleoy lphosphatidyl-ethanolamine (PE-PAA). An acidlabile linker was used to cross-link PAA, forming ALP@CNTs, thus making the system acid sensitive. The release of DOX from ALP@CNTs was found to be higher in an acidic environment. Moreover, near infrared (NIR) light was used to enhance the release of DOX from ALP@CNTs. A CNT-based membrane with controlled diffusion was prepared in the next study. CNTs were used as a component of a cellulose/gel membrane due to their optical property, which allows them to convert NIR light into heat. Poly(Nisopropylacrylamide) (PNIPAm) was used due to its thermo-sensitivity. The properties of both the CNTs and PNIPAm’s were used to control the diffusion of the cargo from the system, under the influence of NIR. CNTs were also used to fabricate an antibacterial agent, for which they were coated with polydopamine (PDA) and decorated with silver particles (Ag). Galactose (Gal) terminated with thiol groups conjugated with the above system was used to strengthen the bacterial targeting ability. The antibacterial activity of

  17. Impact Testing of Stainless Steel Materials

    International Nuclear Information System (INIS)

    R. K. Blandford; D. K. Morton; T. E. Rahl; S. D. Snow

    2005-01-01

    Stainless steels are used for the construction of numerous spent nuclear fuel or radioactive material containers that may be subjected to high strains and moderate strain rates (10 to 200 per second) during accidental drop events. Mechanical characteristics of these materials under dynamic (impact) loads in the strain rate range of concern are not well documented. The goal of the work presented in this paper was to improve understanding of moderate strain rate phenomena on these materials. Utilizing a drop-weight impact test machine and relatively large test specimens (1/2-inch thick), initial test efforts focused on the tensile behavior of specific stainless steel materials during impact loading. Impact tests of 304L and 316L stainless steel test specimens at two different strain rates, 25 per second (304L and 316L material) and 50 per second (304L material) were performed for comparison to their quasi-static tensile test properties. Elevated strain rate stress-strain curves for the two materials were determined using the impact test machine and a ''total impact energy'' approach. This approach considered the deformation energy required to strain the specimens at a given strain rate. The material data developed was then utilized in analytical simulations to validate the final elevated stress-strain curves. The procedures used during testing and the results obtained are described in this paper

  18. Smart Materials Meet Multifunctional Biomedical Devices: Current and Prospective Implications for Nanomedicine

    Directory of Open Access Journals (Sweden)

    Giada Graziana Genchi

    2017-12-01

    Full Text Available With the increasing advances in the fabrication and in monitoring approaches of nanotechnology devices, novel materials are being synthesized and tested for the interaction with biological environments. Among them, smart materials in particular provide versatile and dynamically tunable platforms for the investigation and manipulation of several biological activities with very low invasiveness in hardly accessible anatomical districts. In the following, we will briefly recall recent examples of nanotechnology-based materials that can be remotely activated and controlled through different sources of energy, such as electromagnetic fields or ultrasounds, for their relevance to both basic science investigations and translational nanomedicine. Moreover, we will introduce some examples of hybrid materials showing mutually beneficial components for the development of multifunctional devices, able to simultaneously perform duties like imaging, tissue targeting, drug delivery, and redox state control. Finally, we will highlight challenging perspectives for the development of theranostic agents (merging diagnostic and therapeutic functionalities, underlining open questions for these smart nanotechnology-based devices to be made readily available to the patients in need.

  19. Biopolymers as materials for developing products in pharmaceutical applications and biomedical uses

    OpenAIRE

    Manuel Guillermo Rojas Cortés; Bibiana Margarita Vallejo Díaz; Jairo Ernesto Perilla Perilla

    2008-01-01

    Biopolymers have been widely studied for use in pharmaceutical applications. They have been used for modifying drug release, orientating a drug towards its therapeutic target, penetrating physiological barriers (tissues and cells) and protecting unstable therapeutic agents against physiological conditions which are present in a less invasive administration routes. The importance of biopolymers in designing new biomedical devices must thus be stressed, es-pecially when a pharmaceutical substan...

  20. Fusion Materials Irradiation Test Facility: experimental capabilities and test matrix

    International Nuclear Information System (INIS)

    Opperman, E.K.

    1982-01-01

    This report describes the experimental capabilities of the Fusion Materials Irradiation Test Facility (FMIT) and reference material specimen test matrices. The description of the experimental capabilities and the test matrices has been updated to match the current single test cell facility ad assessed experimenter needs. Sufficient detail has been provided so that the user can plan irradiation experiments and conceptual hardware. The types of experiments, irradiation environment and support services that will be available in FMIT are discussed

  1. Thermal testing of solid neutron shielding materials

    International Nuclear Information System (INIS)

    Boonstra, R.H.

    1992-09-01

    Two legal-weight truck casks the GA-4 and GA-9, will carry four PWR and nine BWR spent fuel assemblies, respectively. Each cask has a solid neutron shielding material separating the steel body and the outer steel skin. In the thermal accident specified by NRC regulations in 10CFR Part 71, the cask is subjected to an 800 degree C environment for 30 minutes. The neutron shield need not perform any shielding function during or after the thermal accident, but its behavior must not compromise the ability of the cask to contain the radioactive contents. In May-June 1989 the first series of full-scale thermal tests was performed on three shielding materials: Bisco Products NS-4-FR, and Reactor Experiments RX-201 and RX-207. The tests are described in Thermal Testing of Solid Neutron Shielding Materials, GA-AL 9897, R. H. Boonstra, General Atomics (1990), and demonstrated the acceptability of these materials in a thermal accident. Subsequent design changes to the cask rendered these materials unattractive in terms of weight or adequate service temperature margin. For the second test series, a material specification was developed for a polypropylene based neutron shield with a softening point of at least 280 degree F. The neutron shield materials tested were boronated (0.8--4.5%) polymers (polypropylene, HDPE, NS-4). The Envirotech and Bisco materials are not polypropylene, but were tested as potential backup materials in the event that a satisfactory polypropylene could not be found

  2. A Survey on Synthesis Processes of Structured Materials for Biomedical Applications: Iron-based Magnetic Nanoparticles, Polymeric Materials and Polymerization Processes.

    Science.gov (United States)

    Neto, Weslany Silvério; Jensen, Alan Thyago; Ferreira, Gabriella Ribeiro; Valadares, Leonardo Fonseca; Gambetta, Rossano; Gonçalves, Sílvia Belém; Machado, Fabricio

    2015-01-01

    Magnetic materials based on iron oxides are extensively designed for several biomedical applications. Heterogeneous polymerization processes are powerful tools for the production of tailored micro-sized and nanosized magneto-polymeric particles. Although several polymerization processes have been adopted along the years, suspension, emulsion and miniemulsion systems deserve special attention due to its ability to produce spherical polymer particles containing magnetic nanoparticles homogeneously dispersed into the polymer thermoplastic matrices. The main objective of this paper is to review the main methods of synthesis of iron-based magnetic nanoparticles and to illustrate how typical polymerization processes in different dispersion medium can be successfully used to produce engineered magnetic core-shell structures. It is exemplified the use of suspension, emulsion and miniemulsion polymerization processes in order to support experimental methodologies required for the production of magnetic polymer particles intended for biomedical applications such as intravascular embolization treatments, drug delivery systems and hyperthermia treatment.

  3. Methods and instruments for materials testing

    Science.gov (United States)

    Hansma, Paul (Inventor); Drake, Barney (Inventor); Rehn, Douglas (Inventor); Adams, Jonathan (Inventor); Lulejian, Jason (Inventor)

    2011-01-01

    Methods and instruments for characterizing a material, such as the properties of bone in a living human subject, using a test probe constructed for insertion into the material and a reference probe aligned with the test probe in a housing. The housing is hand held or placed so that the reference probe contacts the surface of the material under pressure applied either by hand or by the weight of the housing. The test probe is inserted into the material to indent the material while maintaining the reference probe substantially under the hand pressure or weight of the housing allowing evaluation of a property of the material related to indentation of the material by the probe. Force can be generated by a voice coil in a magnet structure to the end of which the test probe is connected and supported in the magnet structure by a flexure, opposing flexures, a linear translation stage, or a linear bearing. Optionally, a measurement unit containing the test probe and reference probe is connected to a base unit with a wireless connection, allowing in the field material testing.

  4. Frictional Ignition Testing of Composite Materials

    Science.gov (United States)

    Peralta, Steve; Rosales, Keisa; Robinson, Michael J.; Stoltzfus, Joel

    2006-01-01

    The space flight community has been investigating lightweight composite materials for use in propellant tanks for both liquid and gaseous oxygen for space flight vehicles. The use of these materials presents some risks pertaining to ignition and burning hazards in the presence of oxygen. Through hazard analysis process, some ignition mechanisms have been identified as being potentially credible. One of the ignition mechanisms was reciprocal friction; however, test data do not exist that could be used to clear or fail these types of materials as "oxygen compatible" for the reciprocal friction ignition mechanism. Therefore, testing was performed at White Sands Test Facility (WSTF) to provide data to evaluate this ignition mechanism. This paper presents the test system, approach, data results, and findings of the reciprocal friction testing performed on composite sample materials being considered for propellant tanks.

  5. Software For Uniaxial Mechanical Testing Of Materials

    Science.gov (United States)

    Mcgaw, M. A.; Pech, D. K.

    1995-01-01

    Materials Testing Software system designed to simplify and automate both routine and not-so-routine materials-testing tasks encountered in laboratory. Supports plan/test/analyze cycle through collection of programs, each optimized to specific task. Gives precise control over nature of command waveforms and acquisition of data, including dynamically variable waveform types, sets of data-acquisition channels, and data rates. Differing command and data-acquisition rates required for exploring creep and fatigue material behavior easily accommodated. Written in Modula-2.

  6. Analytical Ultrasonics in Materials Research and Testing

    Science.gov (United States)

    Vary, A.

    1986-01-01

    Research results in analytical ultrasonics for characterizing structural materials from metals and ceramics to composites are presented. General topics covered by the conference included: status and advances in analytical ultrasonics for characterizing material microstructures and mechanical properties; status and prospects for ultrasonic measurements of microdamage, degradation, and underlying morphological factors; status and problems in precision measurements of frequency-dependent velocity and attenuation for materials analysis; procedures and requirements for automated, digital signal acquisition, processing, analysis, and interpretation; incentives for analytical ultrasonics in materials research and materials processing, testing, and inspection; and examples of progress in ultrasonics for interrelating microstructure, mechanical properites, and dynamic response.

  7. Compression Testing of Textile Composite Materials

    Science.gov (United States)

    Masters, John E.

    1996-01-01

    The applicability of existing test methods, which were developed primarily for laminates made of unidirectional prepreg tape, to textile composites is an area of concern. The issue is whether the values measured for the 2-D and 3-D braided, woven, stitched, and knit materials are accurate representations of the true material response. This report provides a review of efforts to establish a compression test method for textile reinforced composite materials. Experimental data have been gathered from several sources and evaluated to assess the effectiveness of a variety of test methods. The effectiveness of the individual test methods to measure the material's modulus and strength is determined. Data are presented for 2-D triaxial braided, 3-D woven, and stitched graphite/epoxy material. However, the determination of a recommended test method and specimen dimensions is based, primarily, on experimental results obtained by the Boeing Defense and Space Group for 2-D triaxially braided materials. They evaluated seven test methods: NASA Short Block, Modified IITRI, Boeing Open Hole Compression, Zabora Compression, Boeing Compression after Impact, NASA ST-4, and a Sandwich Column Test.

  8. Ares I-X USS Material Testing

    Science.gov (United States)

    Dawicke, David S.; Smith, Stephen W.; Raju, Ivatury S.

    2008-01-01

    An independent assessment was conducted to determine the critical initial flaw size (CIFS) for the flange-to-skin weld in the Ares I-X Upper Stage Simulator (USS). Material characterization tests were conducted to quantify the material behavior for use in the CIFS analyses. Fatigue crack growth rate, Charpy impact, and fracture tests were conducted on the parent and welded A516 Grade 70 steel. The crack growth rate tests confirmed that the material behaved in agreement with literature data and that a salt water environment would not significantly degrade the fatigue resistance. The Charpy impact tests confirmed that the fracture resistance of the material did not have a significant reduction for the expected operational temperatures of the vehicle.

  9. Simple volatility test for bituminous materials

    Energy Technology Data Exchange (ETDEWEB)

    Sharp, J.A.

    1980-04-01

    A simple, inexpensive test measuring the volatility or fuming propensity of bituminous materials with good repeatability has been devised. The test depends on measuring the mass loss which occurs when a small sample of the material is heated in a shallow open dish on a thermostatic hotplate for a fixed time. A rectilinear inverse relation between the mass losses and the softening points of a series of pitches from one source has been found, and the test has been shown to give results which correlate well with other methods for characterizing pitch volatility. Test results obtained with a range of tar products from pitches to creosotes all showed similarly good repeatability. (4 refs.)

  10. A versatile x-ray microtomography station for biomedical imaging and materials research.

    Science.gov (United States)

    Lussani, Fernando Cesar; Vescovi, Rafael Ferreira da Costa; de Souza, Thaís Diniz; Leite, Carlos A P; Giles, Carlos

    2015-06-01

    An x-ray microtomography station implemented at the X-ray Applied Crystallography Laboratory of the State University of Campinas is described. The station is based on a propagation based phase contrast imaging setup with a microfocus source and digital x-ray area detectors. Due to its simplicity, this setup is ideal for fast, high resolution imaging and microtomography of small biological specimens and materials research samples. It can also be coupled to gratings to use and develop new techniques as the harmonic spatial coherent imaging, which allow scattering contrast imaging. Details of the experimental setup, equipment, and software integration are described. Test microtomography for setup commissioning and characterization is shown. We conclude that phase contrast enhanced x-ray imaging and microtomography with resolution below 5 μm voxel size are possible and data sets as wide as 2000 × 2000 × 2000 voxels are obtained with this instrumentation.

  11. Oxygen Compatibility Testing of Composite Materials

    Science.gov (United States)

    Engel, Carl D.; Watkins, Casey N.

    2006-01-01

    Composite materials offer significant weight-saving potential for aerospace applications in propellant and oxidizer tanks. This application for oxygen tanks presents the challenge of being oxygen compatible in addition to complying with the other required material characteristics. This effort reports on the testing procedures and data obtained in examining and selecting potential composite materials for oxygen tank usage. Impact testing of composites has shown that most of these materials initiate a combustion event when impacted at 72 ft-lbf in the presence of liquid oxygen, though testing has also shown substantial variability in reaction sensitivities to impact. Data for screening of 14 potential composites using the Bruceton method is given herein and shows that the 50-percent reaction frequencies range from 17 to 67 ft-lbf. The pressure and temperature rises for several composite materials were recorded to compare the energy releases as functions of the combustion reactions with their respective reaction probabilities. The test data presented are primarily for a test pressure of 300 psia in liquid oxygen. The impact screening process is compared with oxygen index and autogenous ignition test data for both the composite and the basic resin. The usefulness of these supplemental tests in helping select the most oxygen compatible materials is explored. The propensity for mechanical impact ignition of the composite compared with the resin alone is also examined. Since an ignition-free composite material at the peak impact energy of 72 ft-lbf has not been identified, composite reactivity must be characterized over the impact energy level and operating pressure ranges to provide data for hazard analyses in selecting the best potential material for liquid tank usage.

  12. Microstructure, mechanical behavior and biocompatibility of powder metallurgy Nb-Ti-Ta alloys as biomedical material.

    Science.gov (United States)

    Liu, Jue; Chang, Lin; Liu, Hairong; Li, Yongsheng; Yang, Hailin; Ruan, Jianming

    2017-02-01

    Microstructures, mechanical properties, apatite-forming ability and in vitro experiments were studied for Nb-25Ti-xTa (x=10, 15, 20, 25, 35at.%) alloys fabricated by powder metallurgy. It is confirmed that the alloys could achieve a relative density over 80%. Meanwhile, the increase in Ta content enhances the tensile strength, elastic modulus and hardness of the as-sintered alloys. When increasing the sintering temperatures, the microstructure became more homogeneous for β phase, resulting in a decrease in the modulus and strength. Moreover, the alloys showed a good biocompatibility due to the absence of cytotoxic elements, and were suitable for apatite formation and cell adhesion. In conclusion, Nb-25Ti-xTa alloys are potentially useful in biomedical applications with their mechanical and biological properties being evaluated in this work. Copyright © 2016 Elsevier B.V. All rights reserved.

  13. CANMET Gasifier Liner Coupon Material Test Report

    Energy Technology Data Exchange (ETDEWEB)

    Mark Fitzsimmons; Dave Grimmett; Bryan McEnerney

    2007-01-31

    This report provides detailed test results consisting of test data and post-test inspections from Task 1 ''Cooled Liner Coupon Development and Test'' of the project titled ''Development of Technologies and Capabilities for Coal Energy Resources--Advanced Gasification Systems Development (AGSD)''. The primary objective of this development and test program is to verify that ceramic matrix composite (CMC) liner materials planned for use in an advanced gasifier pilot plant will successfully withstand the environments in a commercial gasifier. Pratt & Whitney Rocketdyne (PWR) designed and fabricated the cooled liner test assembly article that was tested in a slagging gasifier at CANMET Energy Technology Center (CETC-O) in Ottawa, Ontario, Canada. The test program conducted in 2006 met the objective of operating the cooled liner test article at slagging conditions in a small scale coal gasifier at CETC-O for over the planned 100 hours. The test hardware was exposed to at least 30 high temperature excursions (including start-up and shut-down cycles) during the test program. The results of the testing has provided valuable information on gasifier startup and required cooling controls in steady state operation of future advanced gasifiers using similar liners. The test program also provided a significant amount of information in the areas of CMC materials and processing for improved capability in a gasifier environment and insight into CMC liner fabrication that will be essential for near-term advanced gasifier projects.

  14. Improved cytotoxicity testing of magnesium materials

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, Janine, E-mail: janine.fischer@hzg.de [Helmholtz-Zentrum Geesthacht, Institute of Materials Research, Department for Structural Research on Macromolecules, Max-Planck Str. 1, D - 21502 Geesthacht (Germany); Proefrock, Daniel [Helmholtz-Zentrum Geesthacht, Institute for Coastal Research, Department for Marine Bioanalytical Chemistry, Max-Planck Str. 1, D - 21502 Geesthacht (Germany); Hort, Norbert [Helmholtz-Zentrum Geesthacht, Institute of Materials Research, Department for Magnesium Processing, Max-Planck Str. 1, D - 21502 Geesthacht (Germany); Willumeit, Regine; Feyerabend, Frank [Helmholtz-Zentrum Geesthacht, Institute of Materials Research, Department for Structural Research on Macromolecules, Max-Planck Str. 1, D - 21502 Geesthacht (Germany)

    2011-06-25

    Metallic magnesium (Mg) and its alloys are highly suitable for medical applications as biocompatible and biodegradable implant materials. Magnesium has mechanical properties similar to bone, stimulates bone regeneration, is an essential non-toxic element for the human body and degrades completely within the body environment. In consequence, magnesium is a promising candidate as implant material for orthopaedic applications. Protocols using the guideline of current ISO standards should be carefully evaluated when applying them for the characterization of the cytotoxic potential of degradable magnesium materials. For as-cast material we recommend using 10 times more extraction medium than recommended by the ISO standards to obtain reasonable results for reliable cytotoxicity rankings of degradable materials in vitro. In addition primary isolated human osteoblasts or mesenchymal stem cells should be used to test magnesium materials.

  15. Sperm toxicity testing: UK best practice guideline from the Association of Biomedical Andrologists.

    Science.gov (United States)

    Long, S; Woodward, B; Tomlinson, M

    2018-02-09

    In order to ensure the quality and integrity of diagnostic semen analysis results, materials used should be tested to ensure that they do not interfere with sperm function. As a toxicity test, complex sperm function testing may be considered controversial, since the fertilizing capacity of single sperm can never be assured. In preference, sperm motility offers a unique means of assessing the toxicity of reagents and materials before they are used in routine practice. Motility is the semen parameter most likely to be influenced by the external environment. Indeed, it is the main reason that laboratories insist on supplying their own approved specimen containers and ensuring that patients, as far as possible, adhere to strict conditions for sample collection and transport prior to testing. This differs to other indirect tests of toxicity such as the mouse embryo assay, whereby the rate of mouse pre-implantation embryo development to the blastocyst stage is compared. This guideline is aimed at health care scientists who deal with andrology in both general pathology and specialised fertility laboratories, and provides a model approach to sperm toxicity testing. For assisted reproduction clinics, the same methodology can be used to test any consumables that are used for sperm processing, and as an indirect guide for any consumables that come into direct contact with oocytes and pre-implantation embryos.

  16. Europa Propulsion Valve Seat Material Testing

    Science.gov (United States)

    Addona, Brad M.

    2017-01-01

    The Europa mission and spacecraft design presented unique challenges for selection of valve seat materials that met the fluid compatibility requirements, and combined fluid compatibility and high radiation exposure level requirements. The Europa spacecraft pressurization system valves will be exposed to fully saturated propellant vapor for the duration of the mission. The effects of Nitrogen Tetroxide (NTO) and Monomethylhydrazine (MMH) propellant vapors on heritage valve seat materials, such as Vespel SP-1 and Polychlorotrifluoroethylene (PCTFE), were evaluated to determine if an alternate material is required. In liquid system applications, Teflon is the only available compatible valve seat material. Radiation exposure data for Teflon in an air or vacuum environment has been previously documented. Radiation exposure data for Teflon in an oxidizer environment such as NTO, was not available, and it was unknown whether the effects would be similar to those on air-exposed samples. Material testing was conducted by Marshall Space Flight Center (MSFC) and White Sands Test Facility (WSTF) to determine the effects of propellant vapor on heritage seat materials for pressurization valve applications, and the effects of combined radiation and NTO propellant exposure on Teflon. The results indicated that changes in heritage pressurization valve seat materials' properties rendered them unsuitable for the Europa application. The combined radiation and NTO exposure testing of Teflon produced results equivalent to combined radiation and air exposure results.

  17. Fuels and materials testing capabilities in Fast Flux Test Facility

    International Nuclear Information System (INIS)

    Baker, R.B.; Chastain, S.A.; Culley, G.E.; Ethridge, J.L.; Lovell, A.J.; Newland, D.J.; Pember, L.A.; Puigh, R.J.; Waltar, A.E.

    1989-01-01

    The Fast Flux Test Facility (FFTF) reactor, which started operating in 1982, is a 400 MWt sodium-cooled fast neutron reactor located in Hanford, Washington State, and operated by Westinghouse Hanford Co. under contract with U.S. Department of Energy. The reactor has a wide variety of functions for irradiation tests and special tests, and its major purpose is the irradiation of fuel and material for liquid metal reactor, nuclear reactor and space reactor projects. The review first describes major technical specifications and current conditions of the FFTF reactor. Then the plan for irradiation testing is outlined focusing on general features, fuel pin/assembly irradiation tests, and absorber irradiation tests. Assemblies for special tests include the material open test assembly (MOTA), fuel open test assembly (FOTA), closed loop in-reactor assembly (CLIRA), and other special fuel assemblies. An interim examination and maintenance cell (FFTF/IEM cell) and other hot cells are used for nondestructive/destructive tests and physical/mechanical properties test of material after irradiation. (N.K.)

  18. Technical features and criteria in designing fiber-reinforced composite materials: from the aerospace and aeronautical field to biomedical applications.

    Science.gov (United States)

    Gloria, Antonio; Ronca, Dante; Russo, Teresa; D'Amora, Ugo; Chierchia, Marianna; De Santis, Roberto; Nicolais, Luigi; Ambrosio, Luigi

    2011-01-01

    Polymer-based composite materials are ideal for applications where high stiffness-to-weight and strength-to-weight ratios are required. From aerospace and aeronautical field to biomedical applications, fiber-reinforced polymers have replaced metals, thus emerging as an interesting alternative. As widely reported, the mechanical behavior of the composite materials involves investigation on micro- and macro-scale, taking into consideration micromechanics, macromechanics and lamination theory. Clinical situations often require repairing connective tissues and the use of composite materials may be suitable for these applications because of the possibility to design tissue substitutes or implants with the required mechanical properties. Accordingly, this review aims at stressing the importance of fiber-reinforced composite materials to make advanced and biomimetic prostheses with tailored mechanical properties, starting from the basic principle design, technologies, and a brief overview of composites applications in several fields. Fiber-reinforced composite materials for artificial tendons, ligaments, and intervertebral discs, as well as for hip stems and mandible models will be reviewed, highlighting the possibility to mimic the mechanical properties of the soft and hard tissues that they replace.

  19. Metrology test object for dimensional verification in additive manufacturing of metals for biomedical applications.

    Science.gov (United States)

    Teeter, Matthew G; Kopacz, Alexander J; Nikolov, Hristo N; Holdsworth, David W

    2015-01-01

    Additive manufacturing continues to increase in popularity and is being used in applications such as biomaterial ingrowth that requires sub-millimeter dimensional accuracy. The purpose of this study was to design a metrology test object for determining the capabilities of additive manufacturing systems to produce common objects, with a focus on those relevant to medical applications. The test object was designed with a variety of features of varying dimensions, including holes, cylinders, rectangles, gaps, and lattices. The object was built using selective laser melting, and the produced dimensions were compared to the target dimensions. Location of the test objects on the build plate did not affect dimensions. Features with dimensions less than 0.300 mm did not build or were overbuilt to a minimum of 0.300 mm. The mean difference between target and measured dimensions was less than 0.100 mm in all cases. The test object is applicable to multiple systems and materials, tests the effect of location on the build, uses a minimum of material, and can be measured with a variety of efficient metrology tools (including measuring microscopes and micro-CT). Investigators can use this test object to determine the limits of systems and adjust build parameters to achieve maximum accuracy. © IMechE 2014.

  20. Erosion testing of hard materials and coatings

    Energy Technology Data Exchange (ETDEWEB)

    Hawk, Jeffrey A.

    2005-04-29

    Erosion is the process by which unconstrained particles, usually hard, impact a surface, creating damage that leads to material removal and component failure. These particles are usually very small and entrained in fluid of some type, typically air. The damage that occurs as a result of erosion depends on the size of the particles, their physical characteristics, the velocity of the particle/fluid stream, and their angle of impact on the surface of interest. This talk will discuss the basics of jet erosion testing of hard materials, composites and coatings. The standard test methods will be discussed as well as alternative approaches to determining the erosion rate of materials. The damage that occurs will be characterized in genera1 terms, and examples will be presented for the erosion behavior of hard materials and coatings (both thick and thin).

  1. In situ buffer material test, (1)

    International Nuclear Information System (INIS)

    Kumata, Masahiro; Muraoka, Susumu; Shimooka, Kenji; Araki, Kunio; Okamoto, Masamichi.

    1987-10-01

    Buffer materials would be placed between a package and wall rock in a disposal pit in a deep geological formation in the concept for geological disposal of high level radioactive wastes. A bentonite powder produced in our country was compacted in a test hole in-situ into 1.27 kg/cm 3 at 380 m below surface and heated with a electric heater about 882 hours. The value of obtained thermal conductivity of the buffer material was slightly larger than those of the laboratory data. The results of the measurements of the moisture of the buffer material using a Neutron Moisture Meter revealed that the buffer material was dried during the heating and groundwater penetrated from fractures of the wall rock into the buffer material after heating was stopped. (author)

  2. Testing of Space Suit Materials for Mars

    Science.gov (United States)

    Larson, Kristine

    2016-01-01

    Human missions to Mars may require radical changes in our approach to EVA suit design. A major challenge is the balance of building a suit robust enough to complete 50 EVAs in the dirt under intense UV exposure without losing mechanical strength or compromising its mobility. We conducted ground testing on both current and new space suit materials to determine performance degradation after exposure to 2500 hours of Mars mission equivalent UV. This testing will help mature the material technologies and provide performance data that can be used by not only the space suit development teams but for all Mars inflatable and soft goods derived structures from airlocks to habitats.

  3. Impact testing of textile composite materials

    Science.gov (United States)

    Portanova, Marc

    1995-01-01

    The objectives of this report were to evaluate the impact damage resistance and damage tolerance of a variety of textile composite materials. Static indentation and impact tests were performed on the stitched and unstitched uniweave composites constructed from AS4/3501-6 Carbon/Epoxy with a fiberglass yarn woven in to hold the fibers together while being stitched. Compression and tension were measured after the tests to determine the damage resistance, residual strength and the damage tolerance of the specimens.

  4. Double Retort System for Materials Compatibility Testing

    International Nuclear Information System (INIS)

    V. Munne; EV Carelli

    2006-01-01

    With Naval Reactors (NR) approval of the Naval Reactors Prime Contractor Team (NRPCT) recommendation to develop a gas cooled reactor directly coupled to a Brayton power conversion system as the Space Nuclear Power Plant (SNPP) for Project Prometheus (References a and b) there was a need to investigate compatibility between the various materials to be used throughout the SNPP. Of particular interest was the transport of interstitial impurities from the nickel-base superalloys, which were leading candidates for most of the piping and turbine components to the refractory metal alloys planned for use in the reactor core. This kind of contamination has the potential to affect the lifetime of the core materials. This letter provides technical information regarding the assembly and operation of a double retort materials compatibility testing system and initial experimental results. The use of a double retort system to test materials compatibility through the transfer of impurities from a source to a sink material is described here. The system has independent temperature control for both materials and is far less complex than closed loops. The system is described in detail and the results of three experiments are presented

  5. Double Retort System for Materials Compatibility Testing

    Energy Technology Data Exchange (ETDEWEB)

    V. Munne; EV Carelli

    2006-02-23

    With Naval Reactors (NR) approval of the Naval Reactors Prime Contractor Team (NRPCT) recommendation to develop a gas cooled reactor directly coupled to a Brayton power conversion system as the Space Nuclear Power Plant (SNPP) for Project Prometheus (References a and b) there was a need to investigate compatibility between the various materials to be used throughout the SNPP. Of particular interest was the transport of interstitial impurities from the nickel-base superalloys, which were leading candidates for most of the piping and turbine components to the refractory metal alloys planned for use in the reactor core. This kind of contamination has the potential to affect the lifetime of the core materials. This letter provides technical information regarding the assembly and operation of a double retort materials compatibility testing system and initial experimental results. The use of a double retort system to test materials compatibility through the transfer of impurities from a source to a sink material is described here. The system has independent temperature control for both materials and is far less complex than closed loops. The system is described in detail and the results of three experiments are presented.

  6. Automation software for a materials testing laboratory

    Science.gov (United States)

    Mcgaw, Michael A.; Bonacuse, Peter J.

    1990-01-01

    The software environment in use at the NASA-Lewis Research Center's High Temperature Fatigue and Structures Laboratory is reviewed. This software environment is aimed at supporting the tasks involved in performing materials behavior research. The features and capabilities of the approach to specifying a materials test include static and dynamic control mode switching, enabling multimode test control; dynamic alteration of the control waveform based upon events occurring in the response variables; precise control over the nature of both command waveform generation and data acquisition; and the nesting of waveform/data acquisition strategies so that material history dependencies may be explored. To eliminate repetitive tasks in the coventional research process, a communications network software system is established which provides file interchange and remote console capabilities.

  7. American Society for Testing and Materials

    CERN Document Server

    ASTM is a not-for-profit organization that provides a forum for the development and publication of voluntary consensus standards for materials, products, systems and services. ASTM develops standard test methods, specifications, practices, guides, classifications, and terminology in 130 areas covering subjects such as metals, paints, plastics, textiles, petroleum, construction, energy, the environment, computerized systems, consumer products, electronics, and many others.

  8. MISSE 6-Testing Materials in Space

    Science.gov (United States)

    Prasad, Narasimha S; Kinard, William H.

    2008-01-01

    The objective of the Materials International Space Station Experiment (MISSE) is to study the performance of novel materials when subjected to the synergistic effects of the harsh space environment by placing them in space environment for several months. In this paper, a few materials and components from NASA Langley Research Center (LaRC) that have been flown on MISSE 6 mission will be discussed. These include laser and optical elements for photonic devices. The pre-characterized MISSE 6 materials were packed inside a ruggedized Passive Experiment Container (PEC) that resembles a suitcase. The PEC was tested for survivability due to launch conditions. Subsequently, the MISSE 6 PEC was transported by the STS-123 mission to International Space Station (ISS) on March 11, 2008. The astronauts successfully attached the PEC to external handrails and opened the PEC for long term exposure to the space environment.

  9. Geometric Modeling of Cellular Materials for Additive Manufacturing in Biomedical Field: A Review

    Science.gov (United States)

    Rosso, Stefano; Meneghello, Roberto; Concheri, Gianmaria

    2018-01-01

    Advances in additive manufacturing technologies facilitate the fabrication of cellular materials that have tailored functional characteristics. The application of solid freeform fabrication techniques is especially exploited in designing scaffolds for tissue engineering. In this review, firstly, a classification of cellular materials from a geometric point of view is proposed; then, the main approaches on geometric modeling of cellular materials are discussed. Finally, an investigation on porous scaffolds fabricated by additive manufacturing technologies is pointed out. Perspectives in geometric modeling of scaffolds for tissue engineering are also proposed. PMID:29487626

  10. Geometric Modeling of Cellular Materials for Additive Manufacturing in Biomedical Field: A Review.

    Science.gov (United States)

    Savio, Gianpaolo; Rosso, Stefano; Meneghello, Roberto; Concheri, Gianmaria

    2018-01-01

    Advances in additive manufacturing technologies facilitate the fabrication of cellular materials that have tailored functional characteristics. The application of solid freeform fabrication techniques is especially exploited in designing scaffolds for tissue engineering. In this review, firstly, a classification of cellular materials from a geometric point of view is proposed; then, the main approaches on geometric modeling of cellular materials are discussed. Finally, an investigation on porous scaffolds fabricated by additive manufacturing technologies is pointed out. Perspectives in geometric modeling of scaffolds for tissue engineering are also proposed.

  11. Standard test method for instrumented impact testing of metallic materials

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2009-01-01

    1.1 This standard establishes the requirements for performing instrumented Charpy V-Notch (CVN) and instrumented Miniaturized Charpy V-Notch (MCVN) impact tests on metallic materials. This method, which is based on experience developed testing steels, provides further information (in addition to the total absorbed energy) on the fracture behavior of the tested materials. Minimum requirements are given for measurement and recording equipment such that similar sensitivity and comparable total absorbed energy measurements to those obtained in Test Methods E 23 and E 2248 are achieved. 1.2 The values stated in SI units are to be regarded as the standard. 1.3 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

  12. From Waste to Healing Biopolymers: Biomedical Applications of Bio-Collagenic Materials Extracted from Industrial Leather Residues in Wound Healing.

    Science.gov (United States)

    Catalina, Mercedes; Cot, Jaume; Borras, Miquel; Lapuente, Joaquín de; González, Javier; Balu, Alina M; Luque, Rafael

    2013-04-29

    The biomedical properties of a porous bio-collagenic polymer extracted from leather industrial waste residues have been investigated in wound healing and tissue regeneration in induced wounds in rats. Application of the pure undiluted bio-collagen to induced wounds in rats dramatically improved its healing after 7 days in terms of collagen production and wound filling as well as in the migration and differentiation of keratinocytes. The formulation tested was found to be three times more effective than the commercial reference product Catrix ® (Heal Progress (HP): 8 ± 1.55 vs. 2.33 ± 0.52, p < 0.001; Formation of Collagen (FC): 7.5 ± 1.05 vs. 2.17 ± 0.75, p < 0.001; Regeneration of Epidermis (RE): 13.33 ± 5.11 vs. 5 ± 5.48, p < 0.05).

  13. Ablative Material Testing at Lewis Rocket Lab

    Science.gov (United States)

    1997-01-01

    The increasing demand for a low-cost, reliable way to launch commercial payloads to low- Earth orbit has led to the need for inexpensive, expendable propulsion systems for new launch vehicles. This, in turn, has renewed interest in less complex, uncooled rocket engines that have combustion chambers and exhaust nozzles fabricated from ablative materials. A number of aerospace propulsion system manufacturers have utilized NASA Lewis Research Center's test facilities with a high degree of success to evaluate candidate materials for application to new propulsion devices.

  14. FMIT - the fusion materials irradiation test facility

    International Nuclear Information System (INIS)

    Liska, D.J.

    1980-01-01

    A joint effort by the Hanford Engineering Development Laboratory (HEDL) and Los Alamos Scientific Laboratory (LASL) has produced a preliminary design for a Fusion Materials Irradiation Test Facility (FMIT) that uses a high-power linear accelerator to fire a deuteron beam into a high-speed jet of molten lithium. The result is a continuous energy spectrum of neutrons with a 14-MeV average energy which can irradiate material samples to projected end-of-life levels in about 3 years, with a total accumulated fluence of 10 21 to 10 22 n/cm 2

  15. Coal Ash Corrosion Resistant Materials Testing

    Energy Technology Data Exchange (ETDEWEB)

    D. K. McDonald; P. L. Daniel; D. J. DeVault

    2007-12-31

    In April 1999, three identical superheater test sections were installed into the Niles Unit No.1 for the purpose of testing and ranking the coal ash corrosion resistance of candidate superheater alloys. The Niles boiler burns high sulfur coal (3% to 3.5%) that has a moderate alkali content (0.2% sodium equivalents), thus the constituents necessary for coal ash corrosion are present in the ash. The test sections were controlled to operate with an average surface metal temperature from approximately 1060 F to 1210 F which was within the temperature range over which coal ash corrosion occurs. Thus, this combination of aggressive environment and high temperature was appropriate for testing the performance of candidate corrosion-resistant tube materials. Analyses of the deposit and scale confirmed that aggressive alkali sulfate constituents were present at the metal surface and active in tube metal wastage. The test sections were constructed so that the response of twelve different candidate tube and/or coating materials could be studied. The plan was to remove and evaluate one of the three test sections at time intervals of 1 year, 3 years, and 5 years. This would permit an assessment of performance of the candidate materials as a function of time. Test Section A was removed in November 2001 after about 24 months of service at the desired steam temperature set point, with about 15.5 months of exposure at full temperature. A progress report, issued in October 2002, was written to document the performance of the candidate alloys in that test section. The evaluation described the condition of each tube sample after exposure. It involved a determination of the rate of wall thickness loss for these samples. In cases where there was more than one sample of a candidate material in the test section, an assessment was made of the performance of the alloy as a function of temperature. Test Sections B and C were examined during the November 2001 outage, and it was decided that

  16. Report of the 1st RCM on ''Nanoscale radiation engineering of advanced materials for potential biomedical applications''. Working document

    International Nuclear Information System (INIS)

    2009-01-01

    There are critical needs for advanced materials in the area of biomaterial engineering, primarily in generating biomaterials of enhanced specific functionalities, improved biocompatibility, and minimal natural rejection but with enhanced interfacial adhesion. These can be achieved by introduction of proper functionalities at the nanoscale dimensions and radiation techniques are uniquely suited for such a task, due to their favorable characteristics, and in most cases, not possible by other methods of synthesis. Accordingly, many of the developing and developed Member States have an interest in creating advanced materials for various health-care applications using a wide array of radiation sources and their broad expertise. The proposal for this CRP was formulated based on the requests and information received from the member states and the conclusions and recommendations of the Consultant’s meeting on “Advanced Materials on the Nano-scale Synthesized by Radiation-Induced Processes”, held on 10-14 December 2007, in Vienna. Based on these conclusions, this CRP aims to support MS to develop methodologies for the use of radiation in the synthesis, modification, and characterization of nanomaterials - nanogels, nanoparticles, nanovehicles, nanoporous membranes, and surfaces with enhanced biocompatibility for potential biomedical applications, such as cell-sheet engineering and artificial tissue construction; diagnostics and imaging; and drug delivery. Additionally, this CRP facilitates networking between radiation technologists and biomedical scientists for the development of such applications. The CRP generated a huge interest, but due to funding constrains, many good proposals had to be rejected. The first RCM of the CRP was convened in Vienna on 30 March - 03 April 2009. It was attended by 14 representatives and two observers. The participants presented and discussed the status of the field, the needs for further research, and various application possibilities

  17. Hydroxyapatites enriched in silicon – Bioceramic materials for biomedical and pharmaceutical applications

    Directory of Open Access Journals (Sweden)

    Katarzyna Szurkowska

    2017-08-01

    Full Text Available Hydroxyapatite (Ca10(PO46(OH2, abbreviated as HA plays a crucial role in implantology, dentistry and bone surgery. Due to its considerable similarity to the inorganic fraction of the mineralized tissues (bones, enamel and dentin, it is used as component in many bone substitutes, coatings of metallic implants and dental materials. Biomaterial engineering often takes advantage of HA capacity for partial ion substitution because the incorporation of different ions in the HA structure leads to materials with improved biological or physicochemical properties. The objective of the work is to provide an overview of current knowledge about apatite materials substituted with silicon ions. Although the exact mechanism of action of silicon in the bone formation process has not been fully elucidated, research has shown beneficial effects of this element on bone matrix mineralization as well as on collagen type I synthesis and stabilization. The paper gives an account of the functions of silicon in bone tissue and outlines the present state of research on synthetic HA containing silicate ions (Si-HA. Finally, methods of HA production as well as potential and actual applications of HA materials modified with silicon ions are discussed.

  18. Testing an integrated behavioural and biomedical model of disability in N-of-1 studies with chronic pain.

    Science.gov (United States)

    Quinn, Francis; Johnston, Marie; Johnston, Derek W

    2013-01-01

    Previous research has supported an integrated biomedical and behavioural model explaining activity limitations. However, further tests of this model are required at the within-person level, because while it proposes that the constructs are related within individuals, it has primarily been tested between individuals in large group studies. We aimed to test the integrated model at the within-person level. Six correlational N-of-1 studies in participants with arthritis, chronic pain and walking limitations were carried out. Daily measures of theoretical constructs were collected using a hand-held computer (PDA), the activity was assessed by self-report and accelerometer and the data were analysed using time-series analysis. The biomedical model was not supported as pain impairment did not predict activity, so the integrated model was supported partially. Impairment predicted intention to move around, while perceived behavioural control (PBC) and intention predicted activity. PBC did not predict activity limitation in the expected direction. The integrated model of disability was partially supported within individuals, especially the behavioural elements. However, results suggest that different elements of the model may drive activity (limitations) for different individuals. The integrated model provides a useful framework for understanding disability and suggests interventions, and the utility of N-of-1 methodology for testing theory is illustrated.

  19. Test System for Thermoelectric Modules and Materials

    Science.gov (United States)

    Hejtmánek, J.; Knížek, K.; Švejda, V.; Horna, P.; Sikora, M.

    2014-10-01

    We present a design for a complex measuring device that enables its user to assess the parameters of power-generating thermoelectric modules (TEMs) (or bulk thermoelectric materials) under a wide range of temperatures ( T cold = 25°C to 90°C, T hot cooled copper-based cooler, (ii) an electrical load system, (iii) a type K thermocouple array connected to a data acquisition computer, and (iv) a thermostatic water-based cooling system with electronically controlled flow rate and temperature of cooling water. Our testing setup represents a useful tool able to assess, e.g., the thermoelectric parameters of newly developed TEMs and materials or to evaluate the thermoelectric parameters of commercially available modules and materials for comparison with values declared by the manufacturer.

  20. Synthesis of irregular graphene oxide tubes using green chemistry and their potential use as reinforcement materials for biomedical applications.

    Directory of Open Access Journals (Sweden)

    Ángel Serrano-Aroca

    Full Text Available Micrometer length tubes of graphene oxide (GO with irregular form were synthesised following facile and green metal complexation reactions. These materials were obtained by crosslinking of GO with calcium, zinc or strontium chlorides at three different temperatures (24, 34 and 55°C using distilled water as solvent for the compounds and following a remarkably simple and low-cost synthetic method, which employs no hazardous substances and is conducted without consumption of thermal or sonic energy. These irregular continuous GO networks showed a very particular interconnected structure by Field Emission Scanning Electron Microscopy with Energy-Disperse X-Ray Spectroscopy for elemental analysis and High-resolution Transmission Electron Microscopy with Scanning Transmission Electron Microscope Dark Field Imaging, and were analysed by Raman Spectroscopy. To demonstrate the potential use of these 3D GO networks as reinforcement materials for biomedical applications, two composites of calcium alginate with irregular tubes of GO and with single GO nanosheets were prepared with the same amount of GO and divalent atoms and analysed. Thus, the dynamic-mechanical modulus of the composites synthesised with the 3D crosslinked GO networks showed a very significant mechanical improvement due to marked microstructural changes confirmed by confocal microscopy, differential scanning calorimetry and Fourier transform infrared spectroscopy.

  1. Emerging chemical strategies for imprinting magnetism in graphene and related 2D materials for spintronic and biomedical applications.

    Science.gov (United States)

    Tuček, Jiří; Błoński, Piotr; Ugolotti, Juri; Swain, Akshaya Kumar; Enoki, Toshiaki; Zbořil, Radek

    2018-03-26

    Graphene, a single two-dimensional sheet of carbon atoms with an arrangement mimicking the honeycomb hexagonal architecture, has captured immense interest of the scientific community since its isolation in 2004. Besides its extraordinarily high electrical conductivity and surface area, graphene shows a long spin lifetime and limited hyperfine interactions, which favors its potential exploitation in spintronic and biomedical applications, provided it can be made magnetic. However, pristine graphene is diamagnetic in nature due to solely sp2 hybridization. Thus, various attempts have been proposed to imprint magnetic features into graphene. The present review focuses on a systematic classification and physicochemical description of approaches leading to equip graphene with magnetic properties. These include introduction of point and line defects into graphene lattices, spatial confinement and edge engineering, doping of graphene lattice with foreign atoms, and sp3 functionalization. Each magnetism-imprinting strategy is discussed in detail including identification of roles of various internal and external parameters in the induced magnetic regimes, with assessment of their robustness. Moreover, emergence of magnetism in graphene analogues and related 2D materials such as transition metal dichalcogenides, metal halides, metal dinitrides, MXenes, hexagonal boron nitride, and other organic compounds is also reviewed. Since the magnetic features of graphene can be readily masked by the presence of magnetic residues from synthesis itself or sample handling, the issue of magnetic impurities and correct data interpretations is also addressed. Finally, current problems and challenges in magnetism of graphene and related 2D materials and future potential applications are also highlighted.

  2. Synthesis of irregular graphene oxide tubes using green chemistry and their potential use as reinforcement materials for biomedical applications.

    Science.gov (United States)

    Serrano-Aroca, Ángel; Deb, Sanjukta

    2017-01-01

    Micrometer length tubes of graphene oxide (GO) with irregular form were synthesised following facile and green metal complexation reactions. These materials were obtained by crosslinking of GO with calcium, zinc or strontium chlorides at three different temperatures (24, 34 and 55°C) using distilled water as solvent for the compounds and following a remarkably simple and low-cost synthetic method, which employs no hazardous substances and is conducted without consumption of thermal or sonic energy. These irregular continuous GO networks showed a very particular interconnected structure by Field Emission Scanning Electron Microscopy with Energy-Disperse X-Ray Spectroscopy for elemental analysis and High-resolution Transmission Electron Microscopy with Scanning Transmission Electron Microscope Dark Field Imaging, and were analysed by Raman Spectroscopy. To demonstrate the potential use of these 3D GO networks as reinforcement materials for biomedical applications, two composites of calcium alginate with irregular tubes of GO and with single GO nanosheets were prepared with the same amount of GO and divalent atoms and analysed. Thus, the dynamic-mechanical modulus of the composites synthesised with the 3D crosslinked GO networks showed a very significant mechanical improvement due to marked microstructural changes confirmed by confocal microscopy, differential scanning calorimetry and Fourier transform infrared spectroscopy.

  3. Textural Properties of Hybrid Biomedical Materials Made from Extracts of Tournefortia hirsutissima L. Imbibed and Deposited on Mesoporous and Microporous Materials

    Directory of Open Access Journals (Sweden)

    Miguel Ángel Hernández

    2016-01-01

    Full Text Available Our research group has developed a group of hybrid biomedical materials potentially useful in the healing of diabetic foot ulcerations. The organic part of this type of hybrid materials consists of nanometric deposits, proceeding from the Mexican medicinal plant Tournefortia hirsutissima L., while the inorganic part is composed of a zeolite mixture that includes LTA, ZSM-5, clinoptilolite, and montmorillonite (PZX as well as a composite material, made of CaCO3 and montmorillonite (NABE. The organic part has been analyzed by GC-MS to detect the most abundant components present therein. In turn, the inorganic supports were characterized by XRD, SEM, and High Resolution Adsorption (HRADS of N2 at 76 K. Through this latter methodology, the external surface area of the hybrid materials was evaluated; besides, the most representative textural properties of each substrate such as total pore volume, pore size distribution, and, in some cases, the volume of micropores were calculated. The formation and stabilization of nanodeposits on the inorganic segments of the hybrid supports led to a partial blockage of the microporosity of the LTA and ZSM5 zeolites; this same effect occurred with the NABE and PZX substrates.

  4. Ultrasonic testing of materials at level 2

    International Nuclear Information System (INIS)

    1988-06-01

    Ultrasonic inspection is a nondestructive method in which high frequency sound waves are introduced into the material being inspected. Ultrasonic testing has a superior penetrating power to radiography and can detect flaws deep in the test specimen (say up to about 6 to 7 meters of steel). It is quite sensitive to small flaws and allows the precise determination of the location and size of the flaws. Basic ultrasonic test methods such as the through transmission method and the resonance method, sensors and testing techniques are described. Pulse echo type flaw detectors and their applications for inspection of welds are surveyed. Ultrasonic standards, calibration of the equipment and evaluation methods are presented. Examples of practical applications in welding, casting and forging processes are given. Figs and tabs

  5. Standard test methods for bend testing of material for ductility

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2009-01-01

    1.1 These test methods cover bend testing for ductility of materials. Included in the procedures are four conditions of constraint on the bent portion of the specimen; a guided-bend test using a mandrel or plunger of defined dimensions to force the mid-length of the specimen between two supports separated by a defined space; a semi-guided bend test in which the specimen is bent, while in contact with a mandrel, through a specified angle or to a specified inside radius (r) of curvature, measured while under the bending force; a free-bend test in which the ends of the specimen are brought toward each other, but in which no transverse force is applied to the bend itself and there is no contact of the concave inside surface of the bend with other material; a bend and flatten test, in which a transverse force is applied to the bend such that the legs make contact with each other over the length of the specimen. 1.2 After bending, the convex surface of the bend is examined for evidence of a crack or surface irregu...

  6. Standard test method for dynamic tear testing of metallic materials

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    1983-01-01

    1.1 This test method covers the dynamic tear (DT) test using specimens that are 3/16 in. to 5/8 in. (5 mm to 16 mm) inclusive in thickness. 1.2 This test method is applicable to materials with a minimum thickness of 3/16 in. (5 mm). 1.3 The pressed-knife procedure described for sharpening the notch tip generally limits this test method to materials with a hardness level less than 36 HRC. Note 1—The designation 36 HRC is a Rockwell hardness number of 36 on Rockwell C scale as defined in Test Methods E 18. 1.4 The values stated in inch-pound units are to be regarded as standard. The values given in parentheses are mathematical conversions to SI units that are provided for information only and are not considered standard. 1.5 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

  7. The interim test effect: testing prior material can facilitate the learning of new material.

    Science.gov (United States)

    Wissman, Kathryn T; Rawson, Katherine A; Pyc, Mary A

    2011-12-01

    A wealth of prior research has shown that testing can improve subsequent learning of the initially tested material. In contrast, only one recent study has shown that an interim test over prior material can improve learning of subsequent new material (i.e., an interim-test effect). Five experiments replicated and extended this initial work by exploring the extent to which interim test effects generalize to complex text material. Participants were prompted to recall each section of an expository text before moving on to study the next section, or were only prompted to recall after the final section. In all experiments, recall of the final, target section was greater when prior sections had received interim tests versus no interim tests. Experiment 3 established that the effect was due to interim testing in particular rather than to intervening activity in general. Experiment 4 established that the effect was not due to test expectancy differences. In contrast to prior research, Experiment 4 also provided evidence that the effect is not due to release from proactive interference. We discuss other possible mechanisms underlying interim-test effects with text, including shifting to more effective encoding strategies.

  8. Material Testing for Robotic Omnidirectional Anchor

    Science.gov (United States)

    Witkoe, Kevin S.

    2012-01-01

    To successfully explore near-Earth Asteroids the question of mobility emerges as the key issue for any robotic mission. When small bodies have extremely low escape velocities, traditional methods, such as wheels, would send the robot hurtling off of the asteroid's surface. To solve this problem, JPL has developed an omni-directional anchoring mechanism for use in microgravity that utilizes microspine technology. These microspines are placed in circular arrays with 16 independent carriages biasing the surface of the rock. The asperities in the surface allow the gripper to hold nearly 150N in all directions. While the gripper has been proven successful on consolidated rocks, it had yet to be tested on a variety of other surfaces that are suspected to separate the large boulders on an asteroid. Since asteroid surfaces vary widely, from friable rocks to lose ponds of regolith, the gripper was tested in a large variety of materials such as, bonded pumice, sand, gravel, and loose rocks. The forces are applied tangent, at 45 degrees, and normal to the surface of the material. The immediate results from this experiment will give insight into the gripper's effectiveness across the wide spectrum of materials found on asteroids.

  9. A smart predictor for material property testing

    International Nuclear Information System (INIS)

    Wang, Wilson; Kanneg, Derek

    2008-01-01

    A reliable predictor is very useful for real-world industrial applications to forecast the future behavior of dynamic systems. A smart predictor, based on a novel recurrent neural fuzzy (RNF) scheme, is developed in this paper for multi-step-ahead prediction of material properties. A systematic investigation based on two benchmark data sets is conducted in terms of performance and efficiency. Analysis results reveal that, of the data-driven forecasting schemes, predictors based on step input patterns outperform those based on sequential input patterns; the RNF predictor outperforms those based on recurrent neural networks and ANFIS schemes in multi-step-ahead prediction of nonlinear time series. An adaptive Levenberg–Marquardt training technique is adopted to improve the robustness and convergence of the RNF predictor. Furthermore, the proposed smart predictor is implemented for material property testing. Investigation results show that the developed RNF predictor is a reliable forecasting tool for material property testing; it can capture and track the system's dynamic characteristics quickly and accurately. It is also a robust predictor to accommodate different system conditions

  10. Mechanics of Granular Materials Test Cell

    Science.gov (United States)

    1998-01-01

    A test cell for Mechanics of Granular Materials (MGM) experiment is shown from all three sides by its video camera during STS-89. Sand and soil grains have faces that can cause friction as they roll and slide against each other, or even cause sticking and form small voids between grains. This complex behavior can cause soil to behave like a liquid under certain conditions such as earthquakes or when powders are handled in industrial processes. Mechanics of Granular Materials (MGM) experiments aboard the Space Shuttle use the microgravity of space to simulate this behavior under conditons that carnot be achieved in laboratory tests on Earth. MGM is shedding light on the behavior of fine-grain materials under low effective stresses. Applications include earthquake engineering, granular flow technologies (such as powder feed systems for pharmaceuticals and fertilizers), and terrestrial and planetary geology. Nine MGM specimens have flown on two Space Shuttle flights. Another three are scheduled to fly on STS-107. The principal investigator is Stein Sture of the University of Colorado at Boulder. Credit: NASA/Marshall Space Flight Center (MSFC)

  11. Radioactive waste material testing capabilities in Romania

    International Nuclear Information System (INIS)

    Vieru, G.

    1999-01-01

    Radioactive material including wastes, generated by Romanian nuclear facilities are packaged in accordance with national and IAEA's Regulation for a safe transport to the disposal center. The evaluation and certification of packages is accomplished by subjecting these packages to normal and simulated test conditions in order to prove the package to technical performances. The standards provide to package designers the possibility to use analysis, testing or a combination of these. The paper describes the experimental and simulating qualification tests for type A packages used for transport and storage of radioactive wastes (low level). Testing are used to substantiate assumptions used in analytical models and to demonstrate package structural response. There are also presented testing capabilities which are used to perform and simulate the required qualification tests. By direct comparison of analysis and experimental results, the degree of reliability of analytical methods and admissibility of assumptions taken in package designing and in demonstrating its safety under conditions of INR - Pitesti, within the contract between the INR - Pitesti and IAEA - Vienna, were determined. (author)

  12. Handbook of Coherent-Domain Optical Methods Biomedical Diagnostics, Environmental Monitoring, and Materials Science

    CERN Document Server

    2013-01-01

    This Handbook provides comprehensive coverage of laser and coherent-domain methods as applied to biomedicine, environmental monitoring, and materials science. Worldwide leaders in these fields describe the fundamentals of light interaction with random media and present an overview of basic research. The latest results on coherent and polarization properties of light scattered by random media, including tissues and blood, speckles formation in multiple scattering media, and other non-destructive interactions of coherent light with rough surfaces and tissues, allow the reader to understand the principles and applications of coherent diagnostic techniques. The expanded second edition has been thoroughly updated with particular emphasis on novel coherent-domain techniques and their applications in medicine and environmental science. Volume 1 describes state-of-the-art methods of coherent and polarization optical imaging, tomography and spectroscopy; diffusion wave spectroscopy; elastic, quasi-elastic and inelasti...

  13. Nondestructive Testing of Materials and Structures

    CERN Document Server

    Akkaya, Yılmaz

    2013-01-01

    Condition assessment and characterization of materials and structures by means of nondestructive testing (NDT) methods is a priority need around the world to meet the challenges associated with the durability, maintenance, rehabilitation, retrofitting, renewal and health monitoring of new and existing infrastructures including historic monuments. Numerous NDT methods that make use of certain components of the electromagnetic and acoustic spectra are currently in use to this effect with various levels of success and there is an intensive worldwide research effort aimed at improving the existing methods and developing new ones. The knowledge and information compiled in this book captures the current state-of-the-art in NDT methods and their application to civil and other engineering materials and structures. Critical reviews and advanced interdisciplinary discussions by world-renowned researchers point to the capabilities and limitations of the currently used NDT methods and shed light on current and future res...

  14. Materials Testing for PV Module Encapsulation

    Energy Technology Data Exchange (ETDEWEB)

    Jorgensen, G.; Terwilliger, K.; Glick, S.; Pern, J.; McMahon, T.

    2003-05-01

    Important physical properties of materials used in PV module packaging are presented. High-moisture-barrier, high-resistivity, adhesion-promoting coatings on polyethyl-ene terephthalate (PET) films have been fabricated and characterized for use in PV module application and com-pared to standard polymer backsheet materials. Ethylene vinyl acetate (EVA) and an encapsulant replacement for EVA are studied for their water vapor transmission rate (WVTR) and adhesion properties. WVTR, at test conditions up to 85C/100% relative humidity (RH), and adhesion val-ues are measured before and after filtered xenon arc lamp ultraviolet (UV) exposure and damp heat exposure at 85C/85% RH. Water ingress is quantified by weight gain and embedded humidity sensors.

  15. Cellulose nanocrystals in nanocomposite approach: Green and high-performance materials for industrial, biomedical and agricultural applications

    Science.gov (United States)

    Fortunati, E.; Torre, L.

    2016-05-01

    The need to both avoid wastes and find new renewable resources has led to a new and promising research based on the possibility to revalorize the biomass producing sustainable chemicals and/or materials which may play a major role in replacing systems traditionally obtained from non-renewable sources. Most of the low-value biomass is termed lignocellulosic, referring to its main constituent biopolymers: cellulose, hemicelluloses and lignin. In this context, nanocellulose, and in particular cellulose nanocrystals (CNC), have gain considerable attention as nanoreinforcement for polymer matrices, mainly biodegradable. Derived from the most abundant polymeric resource in nature and with inherent biodegradability, nanocellulose is an interesting nanofiller for the development of nanocomposites for industrial, biomedical and agricultural applications. Due to the high amount of hydroxyl groups on their surface, cellulose nanocrystals are easy to functionalize. Well dispersed CNC are able, in fact, to enhance several properties of polymers, i.e.: thermal, mechanical, barrier, surface wettability, controlled of active compound and/or drug release. The main objective here is to give a general overview of CNC applications, summarizing our recent developments of bio-based nanocomposite formulations reinforced with cellulose nanocrystals extracted from different natural sources and/or wastes for food packaging, medical and agricultural sectors.

  16. Recent advances in syntheses and biomedical applications of nano-rare earth metal-organic framework materials

    Directory of Open Access Journals (Sweden)

    Xin Pengyan

    2017-12-01

    Full Text Available In recent years,the syntheses of nano-rare earth metal-organic framework (MOF materials and their applications in biomedicine,especially in the diagnosis and treatment of cancer have attracted extensive attentions.On the one hand,nano-rare earth MOFs,which have unique optical and magnetic properties,are promising multimodal imaging contrast agents for biomedical imaging,such as fluorescence imaging and magnetic resonance imaging.On the other hand,nano-rare earth MOFs have various compositions and structures,and excellent intrinsic properties such as large specific surface area,high pore volume and tunable pore size,which enable them to perform as promising nanoplatforms for drug delivery.Therefore,nano-rare earth MOFs may provide a new platform for the development of diagnostic and therapeutic reagents.In this article,the recent advances in the syntheses of nano-rare earth MOFs and their applications in biomedicine are summarized.

  17. Conductive nanostructured materials based on poly-(3,4-ethylenedioxythiophene) (PEDOT) and starch/κ-carrageenan for biomedical applications.

    Science.gov (United States)

    Zamora-Sequeira, Roy; Ardao, Inés; Starbird, Ricardo; García-González, Carlos A

    2018-06-01

    Smart electroactive biomaterials are sought to allow the direct delivery of electrical, electrochemical and electromechanical signals to biological tissues. Specifically, poly-(3,4-ethylenedioxythiophene) (PEDOT) is a polymer of special interest attending to its biocompatibility, tuneable electrical conductivity and processing versatility. In this work, nanostructured PEDOT was synthesized using starch/κ-carrageenan aerogels as templates. κ-carrageenan biopolymer acted as doping agent of the conductive polymer to enhance the biocompatibility and the electrical response. The physicochemical, morphological, mechanical and electrical properties of the nanostructured PEDOT and templates were characterized. The incorporation of κ-carrageenan to the nanostructured materials resulted in an increase in the compressive strength of ca. 40% and a decrease in the electrical impedance of one order-of-magnitude. The synergistic combination of the inherent electrical properties of the PEDOT, the advantageous features of κ-carrageenan as doping agent and the porous morphology of the aerogel template resulted in electroactive PEDOT nanostructures with relevant properties for biomedical applications. Copyright © 2018 Elsevier Ltd. All rights reserved.

  18. ESR (Electronic Spin Resonance Spectroscopy) study of irradiated paper for biomedical material wrapping

    International Nuclear Information System (INIS)

    Huarte, Monica; Rubin de Celis, Emilio; Kairiyama, Eulogia; Zapata, Miguel; Santoro, Natalia; Magnavacca, Cecilia

    2009-01-01

    Ionising radiation treatments are used for sterilization, microbiological decontamination, disinfection, insect disinfestation and food preservation. This ionising radiation generates free radicals (FR) in matter, which can be detected by Electronic Spin Resonance Spectroscopy (ESR). For this work it had analysed different kind of irradiated package papers of syringes, surgical gloves and dressings by ESR. These were irradiated with doses between 20 and 35 kGy of gamma radiation (Cobalt 60). The processed samples were measured in a Bruker ECS 106 spectrometer. The obtained results were: 1-) The irritated samples showed a central peak and two satellites induced by the applied radiation; 2-) The non-irradiated samples did not show the characteristic satellite peaks of the irritated ones; 3-) A linear relationship between the signal heights per unit mass and the applied doses was found; and 4-) The signals were highly stable, with half-time values between 240 and 370 days for 20 and 30 kGy, permitting more than one year of monitoring proceedings. In conclusion, the ESR allows the detection, quantification and time monitoring processes of this kind of irradiated materials. (author) [es

  19. Material testing of reconditioned orthodontic brackets.

    Science.gov (United States)

    Reimann, S; Rewari, A; Keilig, L; Widu, F; Jäger, A; Bourauel, C

    2012-12-01

    While all manufacturers of orthodontic brackets label these products for single use, there are commercial providers offering bracket reconditioning (or "recycling"). We conducted this study to investigate the effects of different recycling techniques on material-related parameters in orthodontic brackets, aiming to derive indications for clinical use and conclusions about the biocompatibility, longevity, and application of recycled brackets. New metal brackets (equilibrium(®); Dentaurum, Ispringen, Germany) were compared to brackets recycled by different techniques, including direct flaming with a Bunsen burner, chemical reconditioning in an acid bath, a commercial unit (Big Jane; Esmadent, IL, USA), and outsourcing to a company (Ortho Clean, Dellstedt, Germany). Material-related examinations included the following: (1) corrosion behavior by static immersion testing and use of a mass spectrometer to determine nickel-ion concentrations in the corrosive medium, (2) surface features in scanning electron micrographs before and after corrosion testing, (3) Vickers hardness using a hardness testing machine, (4) shear bond strength as defined in DIN 13990-1, (5) dimensional stability of the bracket slots by light microscopy, and (6) frictional loss as assessed by an orthodontic measurement and simulation system (OMSS). Each examination was performed on ten brackets. Student's t-test was used for statistical analysis. Compared to the new brackets, those recycled in an acid bath or by a commercial provider revealed significant dimensional changes (p<0.05). Corrosion on the recycled brackets varied according to the recycling techniques employed. The group of brackets recycled by one company revealed hardness values that differed from those of all the other groups. No significant differences were observed in nickel-ion release, frictional loss, and shear bond strength. Recycling was found to significantly reduce the corrosion resistance and dimensional stability of

  20. Aerothermal Testing of Woven TPS Ablative Materials

    Science.gov (United States)

    Stackpoole, Mairead; Feldman, Jay; Olson, Michael; Venkatapathy, Ethiraj

    2012-01-01

    Woven Thermal Protection Systems (WTPS) is a new TPS concept that is funded by NASAs Office of the Chief Technologist (OCT) Game Changing Division. The WTPS project demonstrates the potential for manufacturing a variety of TPS materials capable of wide ranging performances demanded by a spectrum of solar system exploration missions. Currently, missions anticipated to encounter heat fluxes in the range of 1500 4000 Watts per square centimeter are limited to using one proven material fully dense Carbon Phenolic. However, fully dense carbon phenolic is only mass efficient at heat fluxes greater than 4000 Watts per square centimeter, and current mission designs suffer this mass inefficiency for lack of an alternative mid-density TPS. WTPS not only bridges this gap but also offers a replacement for carbon phenolic, which itself requires a significant and costly redevelopment effort to re-establish its capability for use in the high heat flux missions recently prioritized in the NRC Decadal survey, including probe missions to Venus, Saturn and Neptune. This poster will summarize some recent arc jet testing to evaluate the performance of WTPS. Both mid density and fully dense WTPS test results will be presented and results compared to heritage carbon phenolic where applicable.

  1. Proficiency Testing for Evaluating Aerospace Materials Test Anomalies

    Science.gov (United States)

    Hirsch, D.; Motto, S.; Peyton, S.; Beeson, H.

    2006-01-01

    ASTM G 86 and ASTM G 74 are commonly used to evaluate materials susceptibility to ignition in liquid and gaseous oxygen systems. However, the methods have been known for their lack of repeatability. The inherent problems identified with the test logic would either not allow precise identification or the magnitude of problems related to running the tests, such as lack of consistency of systems performance, lack of adherence to procedures, etc. Excessive variability leads to increasing instances of accepting the null hypothesis erroneously, and so to the false logical deduction that problems are nonexistent when they really do exist. This paper attempts to develop and recommend an approach that could lead to increased accuracy in problem diagnostics by using the 50% reactivity point, which has been shown to be more repeatable. The initial tests conducted indicate that PTFE and Viton A (for pneumatic impact) and Buna S (for mechanical impact) would be good choices for additional testing and consideration for inter-laboratory evaluations. The approach presented could also be used to evaluate variable effects with increased confidence and tolerance optimization.

  2. Materials testing and corrosion investigations at KFKI AEKI Materials Department

    Energy Technology Data Exchange (ETDEWEB)

    Nagy, G.; Balog, J.; Kerner, Zs. (and others)

    2004-07-01

    The paper summarises the experimental studies started at the end of the '90s at Materials Department of KFKI Atomic Energy Research Institute (AEKI) in the following research areas: high temperature oxidation kinetics of Zr alloys, high temperature reference electrode testing and stress induced ECP(electrochemical potential) changes in metals. 1. High temperature hydrothermal oxidation of Zr and the properties of Zr oxides were studied by a comparative autoclave test to further our knowledge about the mechanistic understanding of the corrosion phenomenon. The layer thicknesses were determined by weight gain measurements, Rutherford backscattering (RBS), nuclear reaction analysis (NRA) and scanning electron microscopy (SEM). Electrochemical impedance spectra were taken regularly in situ both as a function of oxidation time and temperature, whereas photoelectrochemical response was measured ex situ at room temperature, under illumination with visible light. 2. Within the frame of the LIRES project (supported by the EC within the EURATOM FP5), three high temperature reference electrodes were tested: (i) external Ag/AgCl reference electrode from NRI, Rez, Plc, (ii) Pt-Ir alloy hydrogen electrode from Studsvik Nuclear AB, (iii) Pdhydride reference electrode - Pd(Pt) double polarised active electrode - from VTT Technical Research Centre of Finland. 3. The effect of mechanical stress on electrode potential was studied under zero current conditions. Silver wires in contact with silver-nitrate solutions were exposed to tensile stress and the variation of potential was measured in a two-electrode cell. The study aimed as a first step toward a more detailed theoretical and experimental work aimed to reveal the key factors of the stress corrosion cracking phenomenon. 4. The results of chemical and radiochemical analyses of the primary circuit coolant liquid, obtained between 1995 and 1999 at the four VVER-type blocks of the Paks (Hungary) nuclear power station, were

  3. Decontamination tests on tritium-contaminated materials

    International Nuclear Information System (INIS)

    Boutot, P.; Schipfer, P.

    1967-01-01

    These tests are designed to try out various processes liable to be applied to the decontamination of a material contaminated with tritium. The samples are thin stainless- steel slabs contaminated in the laboratory with elements extracted from industrial installations. The measurement of the initial and residual activities is carried out using an open-window BERTHOLD counter. The best results are obtained by passing a current of pre-heated (300 deg. C) air containing water vapour. This process makes it possible to reach a decontamination factor of 99.5 per cent in 4 hours. In a vacuum, the operation has to be prolonged to 100 hours in order to obtain a decontamination factor of 99.2 per cent. Wet-chemical or electrolytic treatments are efficient but their use is limited by the inherent corrosion risks. A study of the reappearance of the contamination has made it possible to observe that this phenomenon occurs whatever the process used. (authors) [fr

  4. Biomedical signals, imaging, and informatics

    CERN Document Server

    Bronzino, Joseph D

    2014-01-01

    Known as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering.Biomedical Signals, Imaging, and Informatics, the third volume of the handbook, presents material from respected scientists with diverse backgrounds in biosignal processing, medical imaging, infrared imaging, and medical informatics.More than three dozen specific topics are examined, including biomedical s

  5. [The role of animal testing advisory committees in biomedical research in Germany].

    Science.gov (United States)

    Sauer, Ursula G

    2006-01-01

    In accordance with the German Animal Welfare Act, animal experiments in fundamental biomedical research may only be performed after licensing by the responsible authority. This license may only be granted if the experiments are considered indispensable and if the distress of the animals seems ethically acceptable in relation to the purpose of the study. Since 1987 advisory committees have been established to support the authorities in the evaluation of these provisions. Animal welfare organisations had expected case-by-case evaluations of the in-dispensability of research proposals and of the distress of the animals and the scientific benefit of the experiments to take place in these committees, so that such projects that would not meet the criteria of ethical acceptability could be prevented. However, already the lack of parity in the advisory committees alone, in which as a rule four scientists counterpart two representatives from animal welfare organisations, often-times prevents a balanced discussion of these provisions from taking place. Additionally, due to the freedom of science granted in the German Constitution without reservations, until 2002 also the licensing authorities were merely permitted to perform a formal examination of the applications. In the mean time, by including animal welfare as a national objective in the Constitution, the preconditions were made to enable an examination of the contents. From the point of view of animal welfare it therefore is to be requested that now also the advisory committees are ascribed more importance in the course of the licensing procedure and to establish the legal framework for this, if necessary by a revision of the Animal Welfare Act.

  6. [Biomedical informatics].

    Science.gov (United States)

    Capurro, Daniel; Soto, Mauricio; Vivent, Macarena; Lopetegui, Marcelo; Herskovic, Jorge R

    2011-12-01

    Biomedical Informatics is a new discipline that arose from the need to incorporate information technologies to the generation, storage, distribution and analysis of information in the domain of biomedical sciences. This discipline comprises basic biomedical informatics, and public health informatics. The development of the discipline in Chile has been modest and most projects have originated from the interest of individual people or institutions, without a systematic and coordinated national development. Considering the unique features of health care system of our country, research in the area of biomedical informatics is becoming an imperative.

  7. Design of biomedical devices and systems

    CERN Document Server

    King, Paul H

    2008-01-01

    Introduction to Biomedical Engineering Design. Fundamental Design Tools. Design Team Management, Reporting, and Documentation. Product Definition. Product Documentation. Product Development. Hardware Development Methods and Tools. Software Development Methods and Tools. Human Factors. Industrial Design. Biomaterials and Material Testing. Safety Engineering: Devices and Processes. Testing. Analysis of Test Data. Reliability and Liability. Food and Drug Administration. Regulations and Standards. Licensing, Patents, Copyrights, and Trade Secrets. Manufacturing and Quality Control. Miscellaneous Issues. Product Issues. Professional Issues. Design Case Studies. Future Design Issues.

  8. Standard test for nuclear waste materials

    International Nuclear Information System (INIS)

    Nelson, R.D.; Mendel, J.E.; Turcotte, R.P.

    1981-01-01

    The function of the Materials Characterization Center (MCC) is to provide the standardized materials data base and supporting documentation to help ensure safe disposal of nuclear waste. The methods and data are being published in a Nuclear Waste Materials Handbook DOE/TIC 11400. (DG)

  9. Phase Change Material Heat Exchanger Life Test

    Science.gov (United States)

    Lillibridge, Sean; Stephan, Ryan

    2009-01-01

    Low Lunar Orbit (LLO) poses unique thermal challenges for the orbiting space craft, particularly regarding the performance of the radiators. The IR environment of the space craft varies drastically from the light side to the dark side of the moon. The result is a situation where a radiator sized for the maximal heat load in the most adverse situation is subject to freezing on the dark side of the orbit. One solution to this problem is to implement Phase Change Material (PCM) Heat Exchangers. PCM Heat Exchangers act as a "thermal capacitor," storing thermal energy when there is too much being produced by the space craft to reject to space, and then feeding that energy back into the thermal loop when conditions are more favorable. Because they do not use an expendable resource, such as the feed water used by sublimators and evaporators, PCM Heat Exchangers are ideal for long duration LLO missions. In order to validate the performance of PCM Heat Exchangers, a life test is being conducted on four n-Pentadecane, carbon filament heat exchangers. Fluid loop performance, repeatability, and measurement of performance degradation over 2500 melt-freeze cycles will be performed.

  10. Test device for measuring permeability of a barrier material

    Science.gov (United States)

    Reese, Matthew; Dameron, Arrelaine; Kempe, Michael

    2014-03-04

    A test device for measuring permeability of a barrier material. An exemplary device comprises a test card having a thin-film conductor-pattern formed thereon and an edge seal which seals the test card to the barrier material. Another exemplary embodiment is an electrical calcium test device comprising: a test card an impermeable spacer, an edge seal which seals the test card to the spacer and an edge seal which seals the spacer to the barrier material.

  11. Application of a novel reference material in an international round robin test on material emissions testing.

    Science.gov (United States)

    Horn, W; Richter, M; Nohr, M; Wilke, O; Jann, O

    2018-01-01

    Emission testing of products is currently a rapidly increasing field of measurement activity. Labeling procedures for construction products are based on such emission test chamber measurements, and hence, measurement performance should be verified. One possible route is to conduct testing of one material in different laboratories within a round robin test (RRT), ideally using homogeneous reference materials, which can be used within interlaboratory studies or as part of the quality management system to ensure comparable results. The applicability of a lacquer system with nine added VOCs (hexanal, styrene, n-decane, limonene, 2-ethyl-1-hexanol, N-methyl-α-pyrrolidone, 2-ethylhexyl acrylate, dimethyl phthalate, and n-hexadecane) was evaluated in an international RRT with 55 participating laboratories. An intralaboratory quality check confirmed the homogeneity and reproducibility of the lacquer material for most of the compounds (RSD 5%-6%), which was confirmed in the RRT. However, emissions varied for the polar compound N-methyl-α-pyrrolidone and the higher boiling compounds 1,2-dimethyl phthalate, and n-hexadecane which could be traced back to analytical issues. In the RRT, the interlaboratory relative standard deviations (RSDs) ranged from 30% to 65% for all participants but for reference laboratories the range was between 20% and 45%. © 2017 The Authors. Indoor Air published by John Wiley & Sons Ltd.

  12. [Official experimental testing of biomedical products. Regulatory frame and importance of for quality, safety and efficacy].

    Science.gov (United States)

    Vieths, S; Seitz, R

    2014-10-01

    The official experimental testing of biomedicinal products provides a very significant contribution to ensuring quality, safety and efficacy of these indispensable medicines. Already in the prelicensing phase or to elucidate clusters of increased adverse effects, official medicinal control laboratories are committed to perform experimental testing. The official batch release can be seen as external quality control of the manufacturer's release testing. For proficient performance in these tasks, scientific research is required, in particular on the development and refinement of test methods, and considering the continuous development of innovative biomedicinal products. This article is aimed at introducing the present thematic issue and in particular the regulatory basis of experimental product testing, and illustrates by means of several examples its great importance for the sake of the patients.

  13. Engineer Research and Development Center's Materials Testing Center (MTC)

    Data.gov (United States)

    Federal Laboratory Consortium — The Engineer Research and Development Center's Materials Testing Center (MTC) is committed to quality testing and inspection services that are delivered on time and...

  14. Sensor-based supporting mobile system Parkinson disease clinical tests utilising biomedical and RFID technologies

    Directory of Open Access Journals (Sweden)

    Chmielewski Mariusz

    2017-01-01

    Full Text Available This paper discusses method and tool for assisting clinical tests of pharmaceutical drugs utilising sensors and mobile technologies. Emerging sensor and mobile technologies deliver new opportunities to gather and process medical data. Presented analytical approach implements such observations and delivers new, convenient means for remote patient monitoring. Clinical tests are highly specialised process requiring methodology and tools to support such research. Currently available methods rely mostly on analogue approach (booklets, requiring the clinical test participant to fill in health state daily. Such approach often can be biased by unpunctual, not precise reporting. The mobile device can support this process by automatic scheduling and recording an actual time of reports and most of all it can record the inertial and biometric sensor data during the survey process. Presented analytical method (tremors recognition and mobile tool offers consistent approach to clinical test assistance transforming and Android smartphone into remote reporting and notification tool. The tool offers additionally features for sensor based diagnostics support for PD tremor recognition as well as specific clonic and tonic symptoms (dedicated for further system extensions towards epilepsy. Capabilities of the system delivers also RFID mechanisms for efficient on-site clinical test authorisation and configuration. This feature simplifies application installation and automatic set-up considering the participant, clinical test configuration, schedule, smartphone and sensor data. Such a composition delivers convenient and reliable tool which can assist patients and medical staff during the process objectifying the clinical tests results and helping to ensure good quality of the data, quickly available and easily accessible.

  15. Standard leach tests for nuclear waste materials

    International Nuclear Information System (INIS)

    Strachan, D.M.; Barnes, B.O.; Turcotte, R.P.

    1980-01-01

    Five leach tests were conducted to study time-dependent leaching of waste forms (glass). The first four tests include temperature as a variable and the use of three standard leachants. Three of the tests are static and two are dynamic (flow). This paper discusses the waste-form leach tests and presents some representative data. 4 figures

  16. Inpile (in PWR) testing of cladding materials

    International Nuclear Information System (INIS)

    Hahn, R.; Jeong, Y. H.; Baek, B. J.; Kim, K. H.; Kim, S. J.; Choi, B. K.; Kim, J. M.

    1999-04-01

    As an introduction, the reasons to perform inpile tests are depicted. An overview over general inpile test procedure is given, and test details which are necessary for the development of new alloys for high burnup claddings, like sample geometries and measuring techniques for inpile corrosion testing, are described in detail. Tests for the creep and length change behavior of cladding tubes are described briefly. Finally, conclusions are drawn and literature citations for further test details are given. (author). 9 refs., 2 tabs., 17 figs

  17. 21 CFR 660.33 - Testing of source material.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Testing of source material. 660.33 Section 660.33....33 Testing of source material. Except as provided in this section, a sample of each blood... tests shall be resolved by testing with at least one additional antiserum before concluding that the...

  18. Design of online testing system of material radiation resistance

    International Nuclear Information System (INIS)

    Wan Junsheng; He Shengping; Gao Xinjun

    2014-01-01

    The capability of radiation resistance is important for some material used in some specifically engineering fields. It is the same principal applied in all existing test system that compares the performance parameter after radiation to evaluate material radiation resistance. A kind of new technique on test system of material radiation resistance is put forward in this paper. Experimentation shows that the online test system for material radiation resistance works well and has an extending application outlook. (authors)

  19. Survey of hazardous materials used in nuclear testing

    Energy Technology Data Exchange (ETDEWEB)

    Bryant, E.A.; Fabryka-Martin, J.

    1991-02-01

    The use of hazardous'' materials in routine underground nuclear tests at the Nevada Test Site has been reviewed. In addition the inventory of test yields, originally reported in 1976 has been updated. A trail down-hole inventory'' has been conducted for a selected test. The inorganic hazardous materials introduced during testing (with the exception of lead and the fissionable materials) produce an incremental change in the quantity of such materials already present in the geologic media surrounding the test points. 1 ref., 3 tabs.

  20. Data package for the Turkey Point material interaction test capsules

    International Nuclear Information System (INIS)

    Krogness, J.C.; Davis, R.B.

    1979-01-01

    Objective of the Materials Interaction Test (MIT) is to obtain interaction information on candidate package storage materials and geologies under prototypic temperatures in gamma and low level neutron fields. Compatibility, structural properties, and chemical transformations will be studied. The multiple test samples are contained within test capsules connected end-to-end to form a test train. Only passive instrumentation has been used to monitor temperatures and record neutron fluence. The test train contains seven capsules: three to test compatibility, two for structural tests, and two for chemical transformation studies. The materials tested are potential candidates for the spent fuel package canister and repository geologies

  1. Improved Nanomechanical Test Techniques for Surface Engineered Materials

    Directory of Open Access Journals (Sweden)

    Stephen R. Goodes

    2010-06-01

    Full Text Available The development and implementation of a wide range of innovative nanomechanical test techniques to solve tribological problems in applications as diverse as biomedical and automotive are described in this review. For improved wear resistance and durability, the importance of understanding the system response rather than the coating-only properties is emphasized. There are many applications involving mechanical contact where the key to understanding the problem is to test at higher load and to combine reliable measurements taken across different length scales using both nano- and micro-indentation and related wear measurement techniques which more closely simulate contact conditions to fully understand the mechanical behaviour and hence deliver improved application performance. Results are presented with the NanoTest platform for applications for biomedical devices and surface engineering of lightweight alloys for the automotive industry. By combining results with different techniques it is possible to postulate predictive design rules – based on the elastic and plastic deformation energies involved in contact - to aid the reliable optimisation of mechanical properties in the various contact situations in the different applications.

  2. Glass solidification material confinement test device

    International Nuclear Information System (INIS)

    Namiki, Shigekazu.

    1997-01-01

    In a device for confining glass solidification materials, a pipeline connecting a detection vessel and a detector is formed to have a double walled structure, and air blowing holes are formed on the wall of the inner pipe, and an air supply mechanism is connected to inner and outer pipes for supplying blowing air thereby preventing deposition on the inner pipe wall. The air blowing holes are formed by constituting the pipe by using a porous sintered material and porous portions thereof are defined as the air blowing holes, or holes are formed on the pipe wall made of a metal by machining. A blowing boundary layer is formed by blowing the supplied air along the pipe wall of the inner pipe, by which deposition of the sucked materials to the inner wall of the inner pipe is prevented, and all of the materials sucked from the detection vessel are collected to the detector. In addition, an air exit pipe is formed into a double walled structure so as to be supplied blowing air from the air supply mechanism thereby enabling to prevent deposition of sucked materials more reliably. (N.H.)

  3. Double Cantilever Beam Fracture Toughness Testing of Several Composite Materials

    Science.gov (United States)

    Kessler, Jeff A.; Adams, Donald F.

    1992-01-01

    Double-cantilever beam fracture toughness tests were performed by the Composite Materials Research Group on several different unidirectional composite materials provided by NASA Langley Research Center. The composite materials consisted of Hercules IM-7 carbon fiber and various matrix resin formulations. Multiple formulations of four different families of matrix resins were tested: LaRC - ITPI, LaRC - IA, RPT46T, and RP67/RP55. Report presents the materials tested and pertinent details supplied by NASA. For each material, three replicate specimens were tested. Multiple crack extensions were performed on each replicate.

  4. Bearing/Bypass Material-Testing System

    Science.gov (United States)

    Crews, John H., Jr.

    1988-01-01

    System developed to test specimens in compression as well as tension while maintaining constant bearing/bypass ration. Test specimen with centrally located hole is clamped between two bearing-guide plates using one bolt. Bearing-guide plates then secured to two bearing-load cells. Test specimen independently loaded at both ends, using two separate control systems identified as applied and bypass. If two end loads unequal, difference between them reacted as bolt-bearing load on specimen. Throughout test, two control systems synchronized by common input signal (increasing voltage). As result, loads remain proportional as they increase.

  5. Materials Testing in the 21st Century

    Science.gov (United States)

    1988-10-01

    34, Proceedings of the 31st Sagamore Army Materials Research Conference, Plenum Press, NY, 603 pp. (1986). 30. Clay Olaf Ruud and Robert E. Green, Jr., eds...Fort Monmout h, NJ 07703 ATTN: AMSEL-TDD , Mr. T. A. Pfe i ffe r , Technical Dir. Di rector, El ectroni c Technology and Devices Lab, f or t

  6. Examples of testing global identifiability of biological and biomedical models with the DAISY software.

    Science.gov (United States)

    Saccomani, Maria Pia; Audoly, Stefania; Bellu, Giuseppina; D'Angiò, Leontina

    2010-04-01

    DAISY (Differential Algebra for Identifiability of SYstems) is a recently developed computer algebra software tool which can be used to automatically check global identifiability of (linear and) nonlinear dynamic models described by differential equations involving polynomial or rational functions. Global identifiability is a fundamental prerequisite for model identification which is important not only for biological or medical systems but also for many physical and engineering systems derived from first principles. Lack of identifiability implies that the parameter estimation techniques may not fail but any obtained numerical estimates will be meaningless. The software does not require understanding of the underlying mathematical principles and can be used by researchers in applied fields with a minimum of mathematical background. We illustrate the DAISY software by checking the a priori global identifiability of two benchmark nonlinear models taken from the literature. The analysis of these two examples includes comparison with other methods and demonstrates how identifiability analysis is simplified by this tool. Thus we illustrate the identifiability analysis of other two examples, by including discussion of some specific aspects related to the role of observability and knowledge of initial conditions in testing identifiability and to the computational complexity of the software. The main focus of this paper is not on the description of the mathematical background of the algorithm, which has been presented elsewhere, but on illustrating its use and on some of its more interesting features. DAISY is available on the web site http://www.dei.unipd.it/ approximately pia/. 2010 Elsevier Ltd. All rights reserved.

  7. Advanced Mechanical Testing of Sandwich Materials

    DEFF Research Database (Denmark)

    Hayman, Brian; Berggreen, Christian; Jenstrup, Claus

    2008-01-01

    An advanced digital optical system has been used to measure surface strains on sandwich face and core specimens tested in a project concerned with improved criteria for designing sandwich X-joints. The face sheet specimens were of glass reinforced polyester and were tested in tension. The core sp...

  8. Biomedical photonics handbook biomedical diagnostics

    CERN Document Server

    Vo-Dinh, Tuan

    2014-01-01

    Shaped by Quantum Theory, Technology, and the Genomics RevolutionThe integration of photonics, electronics, biomaterials, and nanotechnology holds great promise for the future of medicine. This topic has recently experienced an explosive growth due to the noninvasive or minimally invasive nature and the cost-effectiveness of photonic modalities in medical diagnostics and therapy. The second edition of the Biomedical Photonics Handbook presents fundamental developments as well as important applications of biomedical photonics of interest to scientists, engineers, manufacturers, teachers, studen

  9. Material test data of SUS304 welded joints

    Energy Technology Data Exchange (ETDEWEB)

    Asayama, Tai [Japan Nuclear Cycle Development Inst., Oarai, Ibaraki (Japan). Oarai Engineering Center; Kawakami, Tomohiro [Nuclear Energy System Incorporation, Tokyo (Japan)

    1999-10-01

    This report summarizes the material test data of SUS304 welded joints. Numbers of the data are as follows: Tensile tests 71 (Post-irradiation: 39, Others: 32), Creep tests 77 (Post-irradiation: 20, Others: 57), Fatigue tests 50 (Post-irradiation: 0), Creep-fatigue tests 14 (Post-irradiation: 0). This report consists of the printouts from 'the structural material data processing system'. (author)

  10. Material testing in a linear theta pinch

    International Nuclear Information System (INIS)

    Alani, R.; Azodi, H.; Naraghi, M.; Safaii, B.; Torabi-Fard, A.

    1983-01-01

    The interaction of stainless steel 316 and Inconel 625 alloys has been investigated with a thermonuclear-like plasma, n = 10 16 cm -3 and Tsub(i) = 1 keV, generated in the Alvand I linear theta pinch. The average power flux is 10 7 W/cm 2 and the interaction time nearly one μs. A theoretical analysis based on the formation of an observed impurity layer near the material, has been used to determine the properties of the impurity layer and the extent of the damage on the material. Although arcing has been observed, the dominant damage mechanism has been assessed to be due to evaporation. Exposure to single shots has produced very heavily defective areas and even surface cracks on the SS 316 sample, but no cracks were observed on Inconel 625 after exposure to even 18 shots. On the basis of temperature rise and evaporation a comparison is made among materials exposed to plasmas of a theta pinch, shock tube, present generation tokamak and an anticipated tokamak reactor. (orig.)

  11. Recent developments in dynamic testing of materials

    Directory of Open Access Journals (Sweden)

    Seidt J.D.

    2012-08-01

    Full Text Available Three new testing configurations that have been developed since the last DYMAT conference in 2009 are presented. The first is high strain rate testing of Kevlar cloth and Kevlar yarn in a tensile Split Hopkinson Bar (SHB apparatus. The Kevlar cloth/yarn is attached to the bars by specially designed adaptors that keep the impedance constant. In addition to determining the specimen’s stress and strain from the recorded waves in the bars the deformations are also measured with Digital Image Correlation (DIC. The second testing configuration is a high strain rate shear test for sheet metal. The experiment is done by using a flat notched specimen in a tensile SHB apparatus. The shear strain is measured using DIC within the notch and on the boundary. The third development is a compression apparatus for testing at intermediate strain rates ranging from 20 s−1 to 200 s−1. The apparatus is a combination of a hydraulic actuator and a compression SHB. The stress in the specimen is determined from the stress wave in a very long transmitter bar and the strain and strain rate is determined by using DIC. The results show clean stress strain curves (no ringing.

  12. Disk-bend ductility tests for irradiated materials

    International Nuclear Information System (INIS)

    Klueh, R.L.; Braski, D.N.

    1984-01-01

    We modified the HEDL disk-bend test machine and are using it to qualitatively screen alloys that are susceptible to embrittlement caused by irradiation. Tests designed to understand the disk-bend test in relation to a uniaxial test are discussed. Selected results of tests of neutron-irradiated material are also presented

  13. Mechanics of Granular Materials (MGM) Test Cell

    Science.gov (United States)

    2004-01-01

    Test cells comprise specimen sand contained in a latex membrane (with a grid pattern for CCD cameras) between metal end plates and housed in a water-filled Lexan jacket. Experiment flown on STS-79 and STS-89. Principal Investigator: Dr. Stein Sture.

  14. Test system for thermoelectric modules and materials

    Czech Academy of Sciences Publication Activity Database

    Hejtmánek, Jiří; Knížek, Karel; Švejda, V.; Horna, P.; Sikora, M.

    2014-01-01

    Roč. 43, č. 10 (2014), s. 3726-3732 ISSN 0361-5235 R&D Projects: GA ČR GA13-17538S Institutional support: RVO:68378271 Keywords : thermoelectric power module * automatic thermoelectric testing setup * heat flow measurement * power generation * heat recovery Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 1.798, year: 2014

  15. Advances in biomedical engineering

    CERN Document Server

    Brown, J H U

    1976-01-01

    Advances in Biomedical Engineering, Volume 5, is a collection of papers that deals with application of the principles and practices of engineering to basic and applied biomedical research, development, and the delivery of health care. The papers also describe breakthroughs in health improvements, as well as basic research that have been accomplished through clinical applications. One paper examines engineering principles and practices that can be applied in developing therapeutic systems by a controlled delivery system in drug dosage. Another paper examines the physiological and materials vari

  16. New spark test device for material characterization

    CERN Document Server

    Kildemo, Morten

    2004-01-01

    An automated spark test system based on combining field emission and spark measurements, exploiting a discharging capacitor is investigated. In particular, the remaining charge on the capacitor is analytically solved assuming the field emitted current to follow the Fowler Nordheim expression. The latter allows for field emission measurements from pA to A currents, and spark detection by complete discharge of the capacitor. The measurement theory and experiments on Cu and W are discussed.

  17. Biomedical nanotechnology.

    Science.gov (United States)

    Hurst, Sarah J

    2011-01-01

    This chapter summarizes the roles of nanomaterials in biomedical applications, focusing on those highlighted in this volume. A brief history of nanoscience and technology and a general introduction to the field are presented. Then, the chemical and physical properties of nanostructures that make them ideal for use in biomedical applications are highlighted. Examples of common applications, including sensing, imaging, and therapeutics, are given. Finally, the challenges associated with translating this field from the research laboratory to the clinic setting, in terms of the larger societal implications, are discussed.

  18. Proposal of world network on material testing reactors

    International Nuclear Information System (INIS)

    Takemoto, Noriyuki; Izumo, Hironobu; Hori, Naohiko; Ishitsuka, Etsuo; Ishihara, Masahiro

    2011-01-01

    Establishment of an international cooperation system of worldwide testing reactor network (world network) is proposed in order to achieve efficient facility utilization and provide high quality irradiation data by role sharing of irradiation tests with materials testing reactors in the world. As for the first step, mutual understanding among materials testing reactors is thought to be necessary. From this point, an international symposium on materials testing reactors (ISMTR) was held to construct the world network from 2008, and a common understanding of world network has begun to be shared. (author)

  19. Partial Testing Can Potentiate Learning of Tested and Untested Material from Multimedia Lessons

    Science.gov (United States)

    Yue, Carole L.; Soderstrom, Nicholas C.; Bjork, Elizabeth Ligon

    2015-01-01

    Test-potentiated learning occurs when testing renders a subsequent study period more effective than it would have been without an intervening test. We examined whether testing only a subset of material from a multimedia lesson would potentiate the restudy of both tested and untested material. In Experiments 1a and 1b, participants studied a…

  20. Nuclear fuels for material test reactors

    International Nuclear Information System (INIS)

    Ramanathan, L.V.; Durazzo, M.; Freitas, C.T. de

    1982-01-01

    Experimental results related do the development of nuclear fuels for reactors cooled and moderated by water have been presented cylindrical and plate type fuels have been described in which the core consists of U compouns dispersed in an Al matrix and is clad with aluminium. Fabrication details involving rollmilling, swaging or hot pressing have been described. Corrosion and irradiation test results are also discussed. The performance of the different types of fuels indicates that it is possible to locally fabricate fuel plates with U 3 O 8 +Al cores (20% enriched U) for use in operating Brazilian research reactors. (Author) [pt

  1. State-of-the-art methods for testing materials outdoors

    Science.gov (United States)

    R. Sam Williams

    2004-01-01

    In recent years, computers, sensors, microelectronics, and communication technologies have made it possible to automate the way materials are tested in the field. It is now possible to purchase monitoring equipment to measure weather and materials properties. The measurement of materials response often requires innovative approaches and added expense, but the...

  2. Impact sensitivity test of liquid energetic materials

    Science.gov (United States)

    Tiutiaev, A.; Dolzhikov, A.; Zvereva, I.

    2017-10-01

    This paper presents new experimental method for sensitivity evaluation at the impact. A large number of researches shown that the probability of explosion initiating of liquid explosives by impact depends on the chemical nature and the various external characteristics. But the sensitivity of liquid explosive in the presence of gas bubbles increases many times as compared with the liquid without gas bubbles. In this case local chemical reaction focus are formed as a result of compression and heating of the gas inside the bubbles. In the liquid as a result of convection, wave motion, shock, etc. gas bubbles are easily generated, it is necessary to develop methods for determining sensitivity of liquid explosives to impact and to research the explosives ignition with bubbles. For the experimental investigation, the well-known impact machine and the so-called appliance 1 were used. Instead of the metal cup in the standard method in this paper polyurethane foam cylindrical container with liquid explosive was used. Polyurethane foam cylindrical container is easily deforms by impact. A large number of tests with different liquid explosives were made. It was found that the test liquid explosive to impact in appliance 1 with polyurethane foam to a large extent reflect the real mechanical sensitivity due to the small loss of impact energy on the deformation of the metal cup, as well as the best differentiation liquid explosive sensitivity due to the higher resolution method.

  3. Fatigue testing of materials under extremal conditions by acoustic method

    NARCIS (Netherlands)

    Baranov, VM; Bibilashvili, YK; Karasevich, VA; Sarychev, GA

    2004-01-01

    Increasing fuel cycle time requires fatigue testing of the fuel clad materials for nuclear reactors. The standard high-temperature fatigue tests are complicated and tedious. Solving this task is facilitated by the proposed acoustic method, which ensures observation of the material damage dynamics,

  4. Flammability tests for regulation of building and construction materials

    Science.gov (United States)

    K. Sumathipala

    2006-01-01

    The regulation of building materials and products for flammability is critical to ensure the safety of occupants in buildings and other structures. The involvement of exposed building materials and products in fires resulting in the loss of human life often spurs an increase in regulation and new test methods to address the problem. Flammability tests range from those...

  5. Nuclear material control and accountancy planning and performance testing

    International Nuclear Information System (INIS)

    Mike Enhinger; Dennis Wilkey; Rod Martin; Ken Byers; Brian Smith

    1999-01-01

    An overview of performance testing as used at U.S. Department of Energy facilities is provided. Performance tests are performed on specific aspects of the regulations or site policy. The key issues in establishing a performance testing program are: identifying what needs to be tested; determining how to test; establishing criteria to evaluate test results. The program elements of performance testing program consist of: planning; coordination; conduct; evaluation. A performance test may be conducted of personnel or equipment. The DOE orders for nuclear material control and accountancy are divided into three functional areas: program administration, material accounting, and material control. Examples performance tests may be conducted on program administration, accounting, measurement and measurement control, inventory, and containment [ru

  6. Biomedical Engineering

    CERN Document Server

    Suh, Sang C; Tanik, Murat M

    2011-01-01

    Biomedical Engineering: Health Care Systems, Technology and Techniques is an edited volume with contributions from world experts. It provides readers with unique contributions related to current research and future healthcare systems. Practitioners and researchers focused on computer science, bioinformatics, engineering and medicine will find this book a valuable reference.

  7. Material control test and evaluation system at the ICPP

    International Nuclear Information System (INIS)

    Johnson, C.E.

    1979-01-01

    The US DOE is evaluating process monitoring as part of a total nuclear material safeguards system. A monitoring system is being installed at the Idaho Chemical Processing Plant to test and evaluate material control and surveillance concepts in an operating nuclear fuel reprocessing plant. Process monitoring for nuclear material control complements conventional safeguards accountability and physical protection to assure adherence to approved safeguards procedures and verify containment of nuclear materials within the processing plant

  8. Testing of Materials for Rapid Prototyping Fused Deposition Modelling Technology

    OpenAIRE

    L. Novakova-Marcincinova; J. Novak-Marcincin

    2012-01-01

    Paper presents knowledge about types of test in area of materials properties of selected methods of rapid prototyping technologies. In today used rapid prototyping technologies for production of models and final parts are used materials in initial state as solid, liquid or powder material structure. In solid state are used various forms such as pellets, wire or laminates. Basic range materials include paper, nylon, wax, resins, metals and ceramics. In Fused Deposition Mod...

  9. Tests of composite materials at cryogenic temperatures facilities and results

    CERN Document Server

    Dahlerup-Petersen, K

    1980-01-01

    The design and installation of test facilities for the determination of macromechanical and thermal properties of fiber-reinforced polymer materials at temperatures down to 4.2K are presented. Construction and performance details are given for the following test equipment: quasi- static-tensile and compression-test facilities equipped with an automatic data acquisition system for calculation of material properties, deformation characteristics and various statistics; a thermal contraction-expansion measuring system; a thermal conductivity measurement cell. (1 refs).

  10. Nuclear Materials Management for the Nevada Test Site (NTS)

    International Nuclear Information System (INIS)

    Jesse C. Schreiber

    2007-01-01

    The Nevada Test Site (NTS) has transitioned from its historical role of weapons testing to a broader role that is focused on being a solution to multiple National Nuclear Security Administration (NNSA) challenges and opportunities with nuclear materials for the nation. NTS is supporting other NNSA sites challenged with safe nuclear materials storage and disposition. NNSA, with site involvement, is currently transforming the nuclear stockpile and supporting infrastructure to meet the 2030 vision. Efforts are under way to make the production complex smaller, more consolidated, and more modern. With respect to the nuclear material stockpile, the NNSA sites are currently reducing the complex nuclear material inventory through dispositioning and consolidating nuclear material. This includes moving material from other sites to NTS. State-of-the-art nuclear material management and control practices at NTS are essential for NTS to ensure that these new activities are accomplished in a safe, secure, efficient, and environmentally responsible manner. NTS is aggressively addressing this challenge

  11. The impact of formative testing on study behaviour and study performance of (bio)medical students: a smartphone application intervention study.

    Science.gov (United States)

    Lameris, Anke L; Hoenderop, Joost G J; Bindels, René J M; Eijsvogels, Thijs M H

    2015-04-10

    Formative testing can increase knowledge retention but students often underuse available opportunities. Applying modern technology to make the formative tests more attractive for students could enhance the implementation of formative testing as a learning tool. This study aimed to determine whether formative testing using an internet-based application ("app") can positively affect study behaviour as well as study performance of (bio)medical students. A formative testing app "Physiomics, to the next level" was introduced during a 4-week course to a large cohort (n = 461) of Dutch first year (bio)medical students of the Radboud University. The app invited students to complete 7 formative tests throughout the course. Each module was available for 3-4 days to stimulate the students to distribute their study activities throughout the 4-week course. 72% of the students used the app during the course. Study time significantly increased in intensive users (p Students with an average grade students; students scored the app with a grade of 7.3 ± 1.0 out of 10 and 59% of the students indicated that they would like the app to be implemented in future courses. A smartphone-based application of formative testing is an effective and attractive intervention to stimulate study behaviour and improve study performance in (bio) medical students.

  12. Standard Guide for Testing Polymer Matrix Composite Materials

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2011-01-01

    1.1 This guide summarizes the application of ASTM standard test methods (and other supporting standards) to continuous-fiber reinforced polymer matrix composite materials. The most commonly used or most applicable ASTM standards are included, emphasizing use of standards of Committee D30 on Composite Materials. 1.2 This guide does not cover all possible standards that could apply to polymer matrix composites and restricts discussion to the documented scope. Commonly used but non-standard industry extensions of test method scopes, such as application of static test methods to fatigue testing, are not discussed. A more complete summary of general composite testing standards, including non-ASTM test methods, is included in the Composite Materials Handbook (MIL-HDBK-17). Additional specific recommendations for testing textile (fabric, braided) composites are contained in Guide D6856. 1.3 This guide does not specify a system of measurement; the systems specified within each of the referenced standards shall appl...

  13. A New Tribological Test for Candidate Brush Seal Materials Evaluation

    Science.gov (United States)

    Fellenstein, James A.; Dellacorte, Christopher

    1994-01-01

    A new tribological test for candidate brush seal materials evaluation has been developed. The sliding contact between the brush seal wires and their mating counterface journal is simulated by testing a small tuft of wire against the outside diameter of a high speed rotating shaft. The test configuration is similar to a standard block on ring geometry. The new tester provides the capability to measure both the friction and wear of candidate wire and counterface materials under controlled loading conditions in the gram to kilogram range. A wide test condition latitude of speeds (1 to 27 m/s), temperatures (25 to 700 C), and loads (0.5 to 10 N) enables the simulation of many of the important tribological parameters found in turbine engine brush seals. This paper describes the new test rig and specimen configuration and presents initial data for candidate seal materials comparing tuft test results and wear surface morphology to field tested seal components.

  14. Cryogenic Chamber for Servo-Hydraulic Materials Testing

    Science.gov (United States)

    Francis, John J.; Tuttle, James

    2009-01-01

    A compact cryogenic test chamber can be cooled to approximately 5 to 6 Kelvin for materials testing. The system includes a temperature controller and multiple sensors to measure specimen temperature at different locations. The testing chamber provides a fast and easy method to perform materials testing at lower than liquid nitrogen temperature (77 K). The purpose of the chamber is to cool a composite lap shear specimen to approximately 20 K so that tensile test force and displacement data may be acquired at this cryogenic temperature range.

  15. Supercritical water loop for in-pile materials testing

    Energy Technology Data Exchange (ETDEWEB)

    Ruzickova, M.; Vsolak, R.; Hajek, P.; Zychova, M.; Fukac, R. [Research Centre Rez Ltd., Husinec-Rez (Czech Republic)

    2011-07-01

    The Supercritical Water Loop (SCWL) has been designed and built within the HPLWR Phase 2 project, with the objective of testing materials under supercritical water conditions and radiation. The design parameters are set to 25MPa and 600{sup o}C in the testing area, where material samples shall be located. The loop has recently undergone pressure and leakage tests, during which the strength and tightness of the loop were proved. The loop has been also subjected to the first trial operation at nearly maximum operating parameters (temperature 550 {sup o}C was reached); loop operation was steady during several days. Presently, loop operation is envisaged in order to test the loop's long term operation ability. Samples of a material that needs further testing under out- of-pile conditions shall be exposed in the loop; the choice shall be made in agreement with the results of the WP4 - Materials of the HPLWR Phase 2 project. (author)

  16. Survey test of canister, geology, and fuel cladding material interactions

    International Nuclear Information System (INIS)

    Krogness, J.C.; Almassy, M.Y.; Cantley, D.A.; Davis, R.B.

    1979-08-01

    A series of Material Interaction Test (MIT) is being conducted. The first test is being conducted in the Dry Surface Storage Demonstration at the EMAD facility on NTS. This paper discusses details of this first test and gives a status report on the MIT series. 17 figures

  17. Test plan for the irradiation of nonmetallic materials.

    Energy Technology Data Exchange (ETDEWEB)

    Brush, Laurence H.; Farnum, Cathy Ottinger; Dahl, M.; Joslyn, C. C.; Venetz, T. J.

    2013-05-01

    A comprehensive test program to evaluate nonmetallic materials use in the Hanford tank farms is described in detail. This test program determines the effects of simultaneous multiple stressors at reasonable conditions on in-service configuration components by engineering performance testing.

  18. Test plan for the irradiation of nonmetallic materials.

    Energy Technology Data Exchange (ETDEWEB)

    Brush, Laurence H.; Farnum, Cathy Ottinger; Gelbard, Fred; Dahl, M.; Joslyn, C. C.; Venetz, T. J.

    2013-03-01

    A comprehensive test program to evaluate nonmetallic materials use in the Hanford Tank Farms is described in detail. This test program determines the effects of simultaneous multiple stressors at reasonable conditions on in-service configuration components by engineering performance testing.

  19. Arc Jet Testing of Thermal Protection Materials: 3 Case Studies

    Science.gov (United States)

    Johnson, Sylvia; Conley, Joe

    2015-01-01

    Arc jet testing is used to simulate entry to test thermal protection materials. This paper discusses the usefulness of arc jet testing for 3 cases. Case 1 is MSL and PICA, Case 2 is Advanced TUFROC, and Case 3 is conformable ablators.

  20. Optimum parameters for the production of nano-scale electrospun polycaprolactone to be used as a biomedical material

    Science.gov (United States)

    Ekram, Basma; Abdel-Hady, Bothaina M.; El-kady, Abeer M.; Amr, Sherif M.; Waley, Ahmed I.; Guirguis, Osiris W.

    2017-12-01

    Electrospun nano-polycaprolactone (PCL) is an ideal candidate for biomedical applications, as it mimics the extracellular matrix and possesses good biocompatibility, biodegradability and mechanical properties. Formic acid/acetic acid (FA/AA) and formic acid/acetone (FA/A) solvent systems were reported to be the safest solvents for the preparation of nanoscale electrospun polycaprolactone and they are also a common solvent with many natural polymers. In the present study a comparison between the electrospun fibers produced by the two systems was done. The optimum conditions for preparing PCL nanofibers were studied. The results indicated that finer fibers were found for formic acid/acetic acid in comparison with those produced by formic acid/acetone solvent system. In addition, it was found that optimum conditions for PCL nanofibers electrospinning were detected for 70:30 FA/AA solvent ratio with 15% PCL concentration and a tip to collector distance of 12.5 cm at 20 kV.

  1. Electrofracturing test system and method of determining material characteristics of electrofractured material samples

    Science.gov (United States)

    Bauer, Stephen J.; Glover, Steven F.; Pfeifle, Tom; Su, Jiann-Cherng; Williamson, Kenneth Martin; Broome, Scott Thomas; Gardner, William Payton

    2017-08-01

    A device for electrofracturing a material sample and analyzing the material sample is disclosed. The device simulates an in situ electrofracturing environment so as to obtain electrofractured material characteristics representative of field applications while allowing permeability testing of the fractured sample under in situ conditions.

  2. Physical and chemical test results of electrostatic safe flooring materials

    Science.gov (United States)

    Gompf, R. H.

    1988-01-01

    This test program was initiated because a need existed at the Kennedy Space Center (KSC) to have this information readily available to the engineer who must make the choice of which electrostatic safe floor to use in a specific application. The information, however, should be of value throughout both the government and private industry in the selection of a floor covering material. Included are the test results of 18 floor covering materials which by test evaluation at KSC are considered electrostatically safe. Tests were done and/or the data compiled in the following areas: electrostatics, flammability, hypergolic compatibility, outgassing, floor type, material thickness, and available colors. Each section contains the test method used to gather the data and the test results.

  3. Round-Robin Test of Paraffin Phase-Change Material

    Science.gov (United States)

    Vidi, S.; Mehling, H.; Hemberger, F.; Haussmann, Th.; Laube, A.

    2015-11-01

    A round-robin test between three institutes was performed on a paraffin phase-change material (PCM) in the context of the German quality association for phase-change materials. The aim of the quality association is to define quality and test specifications for PCMs and to award certificates for successfully tested materials. To ensure the reproducibility and comparability of the measurements performed at different institutes using different measuring methods, a round-robin test was performed. The sample was unknown. The four methods used by the three participating institutes in the round-robin test were differential scanning calorimetry, Calvet calorimetry and three-layer calorimetry. Additionally, T-history measurements were made. The aim of the measurements was the determination of the enthalpy as a function of temperature. The results achieved following defined test specifications are in excellent agreement.

  4. Use of cortical neuronal networks for in vitro material biocompatibility testing.

    Science.gov (United States)

    Charkhkar, Hamid; Frewin, Christopher; Nezafati, Maysam; Knaack, Gretchen L; Peixoto, Nathalia; Saddow, Stephen E; Pancrazio, Joseph J

    2014-03-15

    Neural interfaces aim to restore neurological function lost during disease or injury. Novel implantable neural interfaces increasingly capitalize on novel materials to achieve microscale coupling with the nervous system. Like any biomedical device, neural interfaces should consist of materials that exhibit biocompatibility in accordance with the international standard ISO10993-5, which describes in vitro testing involving fibroblasts where cytotoxicity serves as the main endpoint. In the present study, we examine the utility of living neuronal networks as functional assays for in vitro material biocompatibility, particularly for materials that comprise implantable neural interfaces. Embryonic mouse cortical tissue was cultured to form functional networks where spontaneous action potentials, or spikes, can be monitored non-invasively using a substrate-integrated microelectrode array. Taking advantage of such a platform, we exposed established positive and negative control materials to the neuronal networks in a consistent method with ISO 10993-5 guidance. Exposure to the negative controls, gold and polyethylene, did not significantly change the neuronal activity whereas the positive controls, copper and polyvinyl chloride (PVC), resulted in reduction of network spike rate. We also compared the functional assay with an established cytotoxicity measure using L929 fibroblast cells. Our findings indicate that neuronal networks exhibit enhanced sensitivity to positive control materials. In addition, we assessed functional neurotoxicity of tungsten, a common microelectrode material, and two conducting polymer formulations that have been used to modify microelectrode properties for in vivo recording and stimulation. These data suggest that cultured neuronal networks are a useful platform for evaluating the functional toxicity of materials intended for implantation in the nervous system. © 2013 Elsevier B.V. All rights reserved.

  5. Standard Test Method for Testing Nonmetallic Seal Materials by Immersion in a Simulated Geothermal Test Fluid

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    1985-01-01

    1.1 This test method covers a procedure for a laboratory test for performing an initial evaluation (screening) of nonmetallic seal materials by immersion in a simulated geothermal test fluid. 1.2 The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard. 1.3 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use. For specific precautionary statements, see Section 6 and 11.7.

  6. Dredged Material Testing and Evaluation for Ocean Disposal

    Science.gov (United States)

    Evaluation and testing of dredged material proposed for ocean dumping is conducted to help protect human health and the marine environment. National guidance is provided by the Green Book. Regional Implementation Manuals are provided.

  7. Data package for the Turkey Point material interaction test capsules

    International Nuclear Information System (INIS)

    Krogness, J.C.; Davis, R.B.

    1980-02-01

    Objective of the test is to obtain interaction information on candidate package storage materials and geologies under prototypic temperatures in gamma and low-level neutron fields. This document provides a fabrication record of the experiment

  8. Computerization of material test data reporting system : interim report.

    Science.gov (United States)

    1973-09-01

    This study was initiated to provide an integrated system of reporting, storing, and retrieving of construction and material test data using computerized (storage-retrieval) and quality control techniques. The findings reported in this interim report ...

  9. Special Nuclear Material Portal Monitoring at the Nevada Test Site

    International Nuclear Information System (INIS)

    DeAnn Long; Michael Murphy

    2008-01-01

    Prior to April 2007, acceptance and performance testing of the various Special Nuclear Material (SNM) monitoring devices at the Nevada Test Site (NTS) was performed by the Radiological Health Instrumentation department. Calibration and performance testing on the PM-700 personnel portal monitor was performed, but there was no test program for the VM-250 vehicle portal monitor. The handheld SNM monitors, the TSA model 470B, were being calibrated annually, but there was no performance test program. In April of 2007, the Material Control and Accountability Manager volunteered to take over performance testing of all SNM portal monitors at NTS in order to strengthen the program and meet U.S. Department of Energy Order requirements. This paper will discuss the following activities associated with developing a performance testing program: changing the culture, learning the systems, developing and implementing procedures, troubleshooting and repair, validating the process, physical control of equipment, acquisition of new systems, and implementing the performance test program

  10. Correlation of elastomer material properties from small specimen tests and scale-size bearing tests

    International Nuclear Information System (INIS)

    Kulak, R.F.; Hughes, T.H.

    1994-01-01

    Tests were performed on small-size elastomer specimens and scale-size laminated elastomeric bearings to correlate the material properties in shear between the two types of tests. An objective of the tests was to see how well the material properties that were determined from specimen tests could predict the response of scale-size laminated elastomeric bearings. Another objective was to compare the results of specimen test and scale-size bearing test conducted by different testing organizations. A comparison between the test results from different organizations on small specimens showed very good agreement. In contrast, the correlation of scale-size bearing tests showed differences in bearing stiffness

  11. Formation of TiO2 nanotubes via anodization and potential applications for photocatalysts, biomedical materials, and photoelectrochemical cell

    International Nuclear Information System (INIS)

    Sreekantan, Srimala; Saharudin, Khairul Arifah; Wei, Lai Chin

    2011-01-01

    One-dimensional nanotube systems with high surface-to-volume ratios possess unique properties and are thus utilized in various applications. In this study, self-organized TiO 2 nanotubes were prepared by anodization of a Ti foil in glycerol containing 5 wt% ammonium fluoride (NH 4 F) and 6 wt% ethylene glycol (EG). The surface morphology, average inner diameter, and average length of the nanotubes varied with the electrochemical anodization parameters. Nanotubes with uniform surface morphologies, an average diameter of 85 nm, and an average length of 1.1 μm were obtained at 30 V for 1 h The as-prepared nanotubes were amorphous but they crystallized in the anatase phase after heating at about 400 deg. C for 2 h in an argon atmosphere. The photocatalytic activity of the TiO 2 nanotubes was evaluated through the degradation of methyl orange (MO) and by investigating their bactericidal effect. Optimum photocatalysis of MO was achieved at a kinetic rate constant of 10 -3 min -1 . Furthermore, cell viability rapidly decreased on UV illumination and complete killing was achieved at 60 min in the presence of TiO 2 nanotubes. For biomedical applications, the cellular activity on TiO 2 nanotubes was determined using PA6 cells. Higher cellular activities were achieved using the anatase phase of 85-nm-diameter nanotubes than the amorphous phase. Photoelectrochemical hydrogen generation was investigated using nanotube photoanodes in 1 M potassium hydroxide (KOH) containing 1 wt% EG and xenon lamp. The maximum photocurrent density was 0.55 mA/cm 2 . These findings demonstrate that TiO 2 nanotubes are promising for use in multifunctional applications.

  12. Progress and Strategies for Testing of Materials for Solar Panels

    Energy Technology Data Exchange (ETDEWEB)

    Kurtz, Sarah

    2017-04-25

    Accelerated testing is key to confident launch of a new product. However, for new products like solar panels, the best approach is not always clear. The challenge for materials manufacturers is that test times can be long. Also, small-coupon testing may not predict the behavior in the full-size module, but testing of the full-size module is too expensive. As a result, solar panel test standards like IEC 61215 are useful, but are not sufficient. Material manufacturers have needed to define their own test protocols. This presentation will review some historical data (e.g., data show that manufacturers are making great progress toward reducing encapsulant discoloration) and describe advances in material testing (for example, new techniques are being demonstrated on how to more quantitatively assess adhesion, detect tendency for delamination, and understand how encapsulant properties affect other properties like cracking of cells). The International PV Quality Assurance Task Force has been researching climate-specific weathering tests toward the goal of defining international standards that would simplify qualification and quality assurance testing for materials. The status of these tests and the strategies for how to organize these standards to best meet the needs of the industry will be discussed.

  13. FMIT test cell diagnostics: a unique materials challenge

    International Nuclear Information System (INIS)

    Cannon, C.P.; Fuller, J.L.

    1981-08-01

    Basic materials problems are discussed in instrumenting the FMIT test cell, which are applicable to fusion devices in general. Recent data on ceramic-to-metal seals, mineral insulated instrument cables, thermocouples, and optical components are reviewed. The data makes it clear that it would be a mistake to assume that materials and instruments will behave in the FMIT test cell environment as they do in more familiar fission reactors and low power accelerators

  14. Biomedical Shape Memory Polymers

    Directory of Open Access Journals (Sweden)

    SHEN Xue-lin

    2017-07-01

    Full Text Available Shape memory polymers(SMPs are a class of functional "smart" materials that have shown bright prospects in the area of biomedical applications. The novel smart materials with multifunction of biodegradability and biocompatibility can be designed based on their general principle, composition and structure. In this review, the latest process of three typical biodegradable SMPs(poly(lactide acide, poly(ε-caprolactone, polyurethane was summarized. These three SMPs were classified in different structures and discussed, and shape-memory mechanism, recovery rate and fixed rate, response speed was analysed in detail, also, some biomedical applications were presented. Finally, the future development and applications of SMPs are prospected: two-way SMPs and body temperature induced SMPs will be the focus attension by researchers.

  15. Melanin and Melanin-Related Polymers as Materials with Biomedical and Biotechnological Applications-Cuttlefish Ink and Mussel Foot Proteins as Inspired Biomolecules.

    Science.gov (United States)

    Solano, Francisco

    2017-07-18

    The huge development of bioengineering during the last years has boosted the search for new bioinspired materials, with tunable chemical, mechanical, and optoelectronic properties for the design of semiconductors, batteries, biosensors, imaging and therapy probes, adhesive hydrogels, tissue restoration, photoprotectors, etc. These new materials should complement or replace metallic or organic polymers that cause cytotoxicity and some adverse health effects. One of the most interesting biomaterials is melanin and synthetic melanin-related molecules. Melanin has a controversial molecular structure, dependent on the conditions of polymerization, and therefore tunable. It is found in animal hair and skin, although one of the common sources is cuttlefish (Sepia officinalis) ink. On the other hand, mussels synthesize adhesive proteins to anchor these marine animals to wet surfaces. Both melanin and mussel foot proteins contain a high number of catecholic residues, and their properties are related to these groups. Dopamine (DA) can easily polymerize to get polydopamine melanin (PDAM), that somehow shares properties with melanin and mussel proteins. Furthermore, PDAM can easily be conjugated with other components. This review accounts for the main aspects of melanin, as well as DA-based melanin-like materials, related to their biomedical and biotechnological applications.

  16. Melanin and Melanin-Related Polymers as Materials with Biomedical and Biotechnological Applications—Cuttlefish Ink and Mussel Foot Proteins as Inspired Biomolecules

    Directory of Open Access Journals (Sweden)

    Francisco Solano

    2017-07-01

    Full Text Available The huge development of bioengineering during the last years has boosted the search for new bioinspired materials, with tunable chemical, mechanical, and optoelectronic properties for the design of semiconductors, batteries, biosensors, imaging and therapy probes, adhesive hydrogels, tissue restoration, photoprotectors, etc. These new materials should complement or replace metallic or organic polymers that cause cytotoxicity and some adverse health effects. One of the most interesting biomaterials is melanin and synthetic melanin-related molecules. Melanin has a controversial molecular structure, dependent on the conditions of polymerization, and therefore tunable. It is found in animal hair and skin, although one of the common sources is cuttlefish (Sepia officinalis ink. On the other hand, mussels synthesize adhesive proteins to anchor these marine animals to wet surfaces. Both melanin and mussel foot proteins contain a high number of catecholic residues, and their properties are related to these groups. Dopamine (DA can easily polymerize to get polydopamine melanin (PDAM, that somehow shares properties with melanin and mussel proteins. Furthermore, PDAM can easily be conjugated with other components. This review accounts for the main aspects of melanin, as well as DA-based melanin-like materials, related to their biomedical and biotechnological applications.

  17. Capsule development and utilization for material irradiation tests

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Young Hwan; Kim, B. G.; Joo, K. N. [and others

    2000-05-01

    The development program of advanced nuclear structural and fuel materials includes the in-pile tests using the instrumented capsule at HANARO. The tests were performed in the in-core test holes of CT, IR 1 and 2 and OR 4 and 5 of HANARO. Extensive efforts have also been made to establish design and manufacturing technology for the instrumented capsule and its related system, which should be compatible with the HANARO's characteristics. Since the first instrumented capsule(97M-01K) had been designed and successfully fabricated, five tests were done to support the users and provided the economic benefits to user by generating the essential in-pile information on the performance and structural integrity of materials. This paper describes the present status and future plans of these R and D activities for the development of the instrumented capsule including in-situ material property measurement capsules and nuclear fuel test capsules.

  18. Remote-handling demonstration tests for the Fusion Materials Irradiation Test (FMIT) Facility

    International Nuclear Information System (INIS)

    Shen, E.J.; Hussey, M.W.; Kelly, V.P.; Yount, J.A.

    1982-01-01

    The mission of the Fusion Materials Irradiation Test (FMIT) Facility is to create a fusion-like environment for fusion materials development. Crucial to the success of FMIT is the development and testing of remote handling systems required to handle materials specimens and maintenance of the facility. The use of full scale mock-ups for demonstration tests provides the means for proving these systems

  19. Proceedings of the international symposium on materials testing reactors

    International Nuclear Information System (INIS)

    Ishihara, Masahiro; Kawamura, Hiroshi

    2009-01-01

    This report is the Proceedings of the International Symposium on Materials Testing Reactors hosted by Japan Atomic Energy Agency (JAEA). The symposium was held on July 16 to 17, 2008, at the Oarai Research and Development Center of JAEA. This symposium was also held for the 40th anniversary ceremony of Japan Materials Testing Reactor (JMTR) from achieving its first criticality. The objective of the symposium is to exchange the information on current status, future plan and so on among each testing reactors for the purpose of mutual understanding. There were 138 participants from Argentina, Belgium, France, Indonesia, Kazakhstan, Korea, the Russian Federation, Sweden, the United State, Vietnam and Japan. The symposium was divided into four technical sessions and three topical sessions. Technical sessions addressed the general topics of 'status and future plan of materials testing reactors', 'material development for research and testing reactors', irradiation technology (including PIE technology)' and 'utilization with materials testing reactors', and 21 presentations were made. Also the topical sessions addressed 'establishment of strategic partnership', 'management on re-operation work at reactor trouble' and 'basic technology for neutron irradiation tests in MTRs', and panel discussion was made. The 21 of the presented papers are indexed individually. (J.P.N.)

  20. Testing of materials and scale models for impact limiters

    International Nuclear Information System (INIS)

    Maji, A.K.; Satpathi, D.; Schryer, H.L.

    1991-01-01

    Aluminum Honeycomb and Polyurethane foam specimens were tested to obtain experimental data on the material's behavior under different loading conditions. This paper reports the dynamic tests conducted on the materials and on the design and testing of scale models made out of these open-quotes Impact Limiters,close quotes as they are used in the design of transportation casks. Dynamic tests were conducted on a modified Charpy Impact machine with associated instrumentation, and compared with static test results. A scale model testing setup was designed and used for preliminary tests on models being used by current designers of transportation casks. The paper presents preliminary results of the program. Additional information will be available and reported at the time of presentation of the paper

  1. The concept verification testing of materials science payloads

    Science.gov (United States)

    Griner, C. S.; Johnston, M. H.; Whitaker, A.

    1976-01-01

    The concept Verification Testing (CVT) project at the Marshall Space Flight Center, Alabama, is a developmental activity that supports Shuttle Payload Projects such as Spacelab. It provides an operational 1-g environment for testing NASA and other agency experiment and support systems concepts that may be used in shuttle. A dedicated Materials Science Payload was tested in the General Purpose Laboratory to assess the requirements of a space processing payload on a Spacelab type facility. Physical and functional integration of the experiments into the facility was studied, and the impact of the experiments on the facility (and vice versa) was evaluated. A follow-up test designated CVT Test IVA was also held. The purpose of this test was to repeat Test IV experiments with a crew composed of selected and trained scientists. These personnel were not required to have prior knowledge of the materials science disciplines, but were required to have a basic knowledge of science and the scientific method.

  2. Tests of candidate materials for particle bed reactors

    International Nuclear Information System (INIS)

    Horn, F.L.; Powell, J.R.; Wales, D.

    1987-01-01

    Rhenium metal hot frits and zirconium carbide-coated fuel particles appear suitable for use in flowing hydrogen to at least 2000 K, based on previous tests. Recent tests on alternate candidate cooled particle and frit materials are described. Silicon carbide-coated particles began to react with rhenium frit material at 1600 K, forming a molten silicide at 2000 K. Silicon carbide was extensively attacked by hydrogen at 2066 K for 30 minutes, losing 3.25% of its weight. Vitrous carbon was also rapidly attacked by hydrogen at 2123 K, losing 10% of its weight in two minutes. Long term material tests on candidate materials for closed cycle helium cooled particle bed fuel elements are also described. Surface imperfections were found on the surface of pyrocarbon-coated fuel particles after ninety days exposure to flowing (∼500 ppM) impure helium at 1143 K. The imperfections were superficial and did not affect particle strength

  3. Arcjet Testing of Micro-Meteoroid Impacted Thermal Protection Materials

    Science.gov (United States)

    Agrawal, Parul; Munk, Michelle M.; Glaab, Louis J.

    2013-01-01

    There are several harsh space environments that could affect thermal protection systems and in turn pose risks to the atmospheric entry vehicles. These environments include micrometeoroid impact, extreme cold temperatures, and ionizing radiation during deep space cruise, all followed by atmospheric entry heating. To mitigate these risks, different thermal protection material samples were subjected to multiple tests, including hyper velocity impact, cold soak, irradiation, and arcjet testing, at various NASA facilities that simulated these environments. The materials included a variety of honeycomb packed ablative materials as well as carbon-based non-ablative thermal protection systems. The present paper describes the results of the multiple test campaign with a focus on arcjet testing of thermal protection materials. The tests showed promising results for ablative materials. However, the carbon-based non-ablative system presented some concerns regarding the potential risks to an entry vehicle. This study provides valuable information regarding the capability of various thermal protection materials to withstand harsh space environments, which is critical to sample return and planetary entry missions.

  4. Test plan for buried waste containment system materials

    International Nuclear Information System (INIS)

    Weidner, J.; Shaw, P.

    1997-03-01

    The objectives of the FY 1997 barrier material work at the Idaho National Engineering and Environmental Laboratory are to (1) select a waste barrier material and verify that it is compatible with the Buried Waste Containment System Process, and (2) determine if, and how, the Buried Waste Containment System emplacement process affects the material properties and performance (on proof of principle scale). This test plan describes a set of measurements and procedures used to validate a waste barrier material for the Buried Waste Containment System. A latex modified proprietary cement manufactured by CTS Cement Manufacturing Company will be tested. Emplacement properties required for the Buried Waste Containment System process are: slump between 8 and 10 in., set time between 15 and 30 minutes, compressive strength at set of 20 psi minimum, and set temperature less than 100 degrees C. Durability properties include resistance to degradation from carbonate, sulfate, and waste-site soil leachates. A set of baseline barrier material properties will be determined to provide a data base for comparison with the barrier materials when tested in the field. The measurements include permeability, petrographic analysis to determine separation and/or segregation of mix components, and a set of mechanical properties. The measurements will be repeated on specimens from the field test material. The data will be used to determine if the Buried Waste Containment System equipment changes the material. The emplacement properties will be determined using standard laboratory procedures and instruments. Durability of the barrier material will be evaluated by determining the effect of carbonate, sulfate, and waste-site soil leachates on the compressive strength of the barrier material. The baseline properties will be determined using standard ASTM procedures. 9 refs., 1 fig., 2 tabs

  5. Development, simulation and testing of structural materials for DEMO

    International Nuclear Information System (INIS)

    Laesser, R.; Baluc, N.; Boutard, J.-L.; Diegele, E.; Gasparotto, M.; Riccardi, B.; Dudarev, S.; Moeslang, A.; Pippan, R.; Schaaf, B. van der

    2006-01-01

    In DEMO the structural and functional materials of the in-vessel components will be exposed to a very intense flux of fusion neutrons with energies up to 14 MeV creating displacement cascades and gaseous transmutation products. Point defects and transmutations will induce new microstructures leading to changes in mechanical and physical properties such as hardening, swelling, loss of fracture toughness and creep strength. The kinetics of microstructural evolution depends on time, temperature and defect production rates. The structural materials to be used in DEMO should have very special properties: high radiation resistance up to the dose of 100 dpa, low residual activation, high creep strength and good compatibility with the cooling media in as wide a temperature operational window as possible for the achievement of high thermal efficiency. The most promising materials are: Reduced Activation Ferritic Martensitic (RAFM) steels (Eurofer and F82H), Oxide Dispersion Strengthened (ODS) RAFM and RAF steels, SiC fibres reinforced SiC matrix composites (SiCf/SiC), tungsten (W) and W-alloys. Each of these materials has its advantages and drawbacks and will be best used under certain conditions. Presently the best studied group of materials are the RAFM steels. They require the smallest extrapolation for use in DEMO but also offer the lowest upper temperature limit of operation (550 o C) and thus the lowest thermal efficiency. The other materials foreseen for more advanced breeder blanket and divertor concepts require intense fundamental R(and)D and testing before their acceptance, whereas the so-called Test Blanket Modules (TBMs) will be constructed using RAFM steel and tested in ITER. Validation of the DEMO structural materials will be done in IFMIF, the International Fusion Materials Irradiation Facility, which will produce neutron damage and transmutation products very similar to those characterising a fusion device and will allow accelerated testing with damage rates

  6. High Temperature Ultrasonic Transducers : Material Selection and Testing

    Science.gov (United States)

    Bar-Cohen, Yoseph; Bruno, Alessandro

    2012-01-01

    The task of my two-months internship was to test different materials to be used to build an high temperature transducer, to develop some prototypes and to test their performance, to assess the reliability of commercial product rated for such a temperature, as well as to collaborate in developing the signal processing code to measure the condensed water levels.

  7. An Approach to the Flammability Testing of Aerospace Materials

    Science.gov (United States)

    Hirsch, David B.

    2012-01-01

    Presentation reviews: (1) Current approach to evaluation of spacecraft materials flammability (2) The need for and the approach to alternative routes (3) Examples of applications of the approach recommended a) Crew Module splash down b) Crew Module depressurization c) Applicability of NASA's flammability test data to other sample configurations d) Applicability of NASA's ground flammability test data to spacecraft environments

  8. 40 CFR 59.208 - Charcoal lighter material testing protocol.

    Science.gov (United States)

    2010-07-01

    ... already impregnated or treated in the charcoal; (2) How to use or apply the lighter material; and (3) How... reference point reading during each test run using a chart recorder or once every 20 seconds if using Method... test run to measure the real time organic concentration of the exhaust as methane. Record the emission...

  9. Application of thermal neutrons in testing of nuclear facilities materials

    International Nuclear Information System (INIS)

    Milczarek, J.J.

    2008-01-01

    Recent applications of thermal neutrons in testing of materials used in nuclear facilities are presented. The neutron radiography technique, characterization of residual stresses with neutron diffraction and small angle neutron scattering is considered in some detail. The results of testing of fuel elements, steel used for pressurized reactor vessels and changes induced in control rods are discussed. (author)

  10. Testing the protective performance of clothing materials against aerosols

    NARCIS (Netherlands)

    Tuinman, I.L.; Ort, G.

    2010-01-01

    In AEP 38, skin protection against aerosol particles offered by CBRN protective equipment is recognized as an important issue that has to be verified. The work presented here focuses on material (i.e. swatch) tests, as opposed to whole system tests that use mannequins or human volunteers and which

  11. Atomistic Simulations of Small-scale Materials Tests of Nuclear Materials

    International Nuclear Information System (INIS)

    Shin, Chan Sun; Jin, Hyung Ha; Kwon, Jun Hyun

    2012-01-01

    Degradation of materials properties under neutron irradiation is one of the key issues affecting the lifetime of nuclear reactors. Evaluating the property changes of materials due to irradiations and understanding the role of microstructural changes on mechanical properties are required for ensuring reliable and safe operation of a nuclear reactor. However, high dose of neuron irradiation capabilities are rather limited and it is difficult to discriminate various factors affecting the property changes of materials. Ion beam irradiation can be used to investigate radiation damage to materials in a controlled way, but has the main limitation of small penetration depth in the length scale of micro meters. Over the past decade, the interest in the investigations of size-dependent mechanical properties has promoted the development of various small-scale materials tests, e.g. nanoindentation and micro/nano-pillar compression tests. Small-scale materials tests can address the issue of the limitation of small penetration depth of ion irradiation. In this paper, we present small-scale materials tests (experiments and simulation) which are applied to study the size and irradiation effects on mechanical properties. We have performed molecular dynamics simulations of nanoindentation and nanopillar compression tests. These atomistic simulations are expected to significantly contribute to the investigation of the fundamental deformation mechanism of small scale irradiated materials

  12. Growing and testing mycelium bricks as building insulation materials

    Science.gov (United States)

    Xing, Yangang; Brewer, Matthew; El-Gharabawy, Hoda; Griffith, Gareth; Jones, Phil

    2018-02-01

    In order to improve energy performance of buildings, insulation materials (such as mineral glass and rock wools, or fossil fuel-based plastic foams) are being used in increasing quantities, which may lead to potential problem with materials depletions and landfill disposal. One sustainable solution suggested is the use of bio-based, biodegradable materials. A number of attempts have been made to develop biomaterials, such as sheep wood, hemcrete or recycled papers. In this paper, a novel type of bio insulation materials - mycelium is examined. The aim is to produce mycelium materials that could be used as insulations. The bio-based material was required to have properties that matched existing alternatives, such as expanded polystyrene, in terms of physical and mechanical characteristics but with an enhanced level of biodegradability. The testing data showed mycelium bricks exhibited good thermal performance. Future work is planned to improve growing process and thermal performance of the mycelium bricks.

  13. Reprint of: Improved cytotoxicity testing of magnesium materials

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, Janine, E-mail: janine.fischer@hzg.de [Helmholtz-Zentrum Geesthacht, Institute of Materials Research, Department for Structural Research on Macromolecules, Max-Planck Str. 1, D - 21502 Geesthacht (Germany); Proefrock, Daniel [Helmholtz-Zentrum Geesthacht, Institute for Coastal Research, Department for Marine Bioanalytical Chemistry, Max-Planck Str. 1, D - 21502 Geesthacht (Germany); Hort, Norbert [Helmholtz-Zentrum Geesthacht, Institute of Materials Research, Department for Magnesium Processing, Max-Planck Str. 1, D - 21502 Geesthacht (Germany); Willumeit, Regine; Feyerabend, Frank [Helmholtz-Zentrum Geesthacht, Institute of Materials Research, Department for Structural Research on Macromolecules, Max-Planck Str. 1, D - 21502 Geesthacht (Germany)

    2011-12-15

    Metallic magnesium (Mg) and its alloys are highly suitable for medical applications as biocompatible and biodegradable implant materials. Magnesium has mechanical properties similar to bone, stimulates bone regeneration, is an essential non-toxic element for the human body and degrades completely within the body environment. In consequence, magnesium is a promising candidate as implant material for orthopaedic applications. Protocols using the guideline of current ISO standards should be carefully evaluated when applying them for the characterization of the cytotoxic potential of degradable magnesium materials. For as-cast material we recommend using 10 times more extraction medium than recommended by the ISO standards to obtain reasonable results for reliable cytotoxicity rankings of degradable materials in vitro. In addition primary isolated human osteoblasts or mesenchymal stem cells should be used to test magnesium materials.

  14. Piezoelectric materials involved in road traffic applications test system

    International Nuclear Information System (INIS)

    Vazquez Rodriguez, M.; Jimenez Martinez, F.; Frutos, J. de

    2011-01-01

    The test bench system described in this paper performs experiments on piezoelectric materials used in road traffic applications, covering a range between 14 and 170 km/h, which is considered enough for testing under standard traffic conditions. A software has been developed to control the three phase induction motor driver and to acquire all the measurement data of the piezoelectric materials. The mass over each systems axis can be selected, with a limit of 60 kg over each wheel. The test bench is used to simulate the real behaviour of buried piezoelectric cables in road traffic applications for both light and heavy vehicles. This new test bed system is a powerful research tool and can be applied to determine the optimal installation and configuration of the piezoelectric cable sensors and opens a new field of research: the study of energy harvesting techniques based on piezoelectric materials. (Author) 10 refs.

  15. Elevated Temperature Testing and Modeling of Advanced Toughened Ceramic Materials

    Science.gov (United States)

    Keith, Theo G.

    2005-01-01

    The purpose of this report is to provide a final report for the period of 12/1/03 through 11/30/04 for NASA Cooperative Agreement NCC3-776, entitled "Elevated Temperature Testing and Modeling of Advanced Toughened Ceramic Materials." During this final period, major efforts were focused on both the determination of mechanical properties of advanced ceramic materials and the development of mechanical test methodologies under several different programs of the NASA-Glenn. The important research activities made during this period are: 1. Mechanical properties evaluation of two gas-turbine grade silicon nitrides. 2) Mechanical testing for fuel-cell seal materials. 3) Mechanical properties evaluation of thermal barrier coatings and CFCCs and 4) Foreign object damage (FOD) testing.

  16. Polymer-Block-Polypeptides and Polymer-Conjugated Hybrid Materials as Stimuli-Responsive Nanocarriers for Biomedical Applications.

    Science.gov (United States)

    John, Johnson V; Johnson, Renjith P; Heo, Min Seon; Moon, Byeong Kyu; Byeon, Seong Jin; Kim, Il

    2015-01-01

    Stimuli-responsive nanocarriers are a class of soft materials that includes natural polymers, synthetic polymers, and polypeptides. Recently, modern synthesis tools such as atom transfer radical polymerization, reversible addition-fragmentation chain transfer polymerization, nitroxide-mediated radical polymerization, ring-opening polymerization of α-amino acid N-carboxyanhydrides, and various "click" chemistry strategies were simultaneously employed for the design and synthesis of nanosized drug delivery vehicles. Importantly, the research focused on the improvement of the nanocarrier targetability and the site-specific, triggered release of therapeutics with high drug loading efficiency and minimal drug leakage during the delivery to specific targets. In this context, nanocarriers responsive to common stimuli such as pH, temperature, redox potential, light, etc. have been widely used for the controlled delivery of therapeutics to pathological sites. Currently, different synthesis and self-assembly strategies improved the drug loading efficacy and targeted delivery of therapeutic agents to the desired site. In particular, polypeptide-containing hybrid materials have been developed for the controlled delivery of therapeutic agents. Therefore, stimuli-sensitive synthetic polypeptide-based materials have been extensively investigated in recent years. This review focuses on recent advances in the development of polymer-block-polypeptides and polymer-conjugated hybrid materials that have been designed and evaluated for various stimuli-responsive drug and gene delivery applications.

  17. Testing of DentStat (trademark) and Competing Dental Materials

    Science.gov (United States)

    2014-06-13

    comparisons, DS showed the highest values, and in flexural modulus, 13 it was the second stiffest among the tested dental restoratives and cements ...NAVAL MEDICAL RESEARCH UNIT SAN ANTONIO TESTING OF DENTST AT™ AND COMPETING DENTAL MATERIALS Y OON HWANG PHD, JONATHAN STAHL DDS PHD, WAYNE M. D...LtCOL Wen Lien of the US Air Force Dental Evaluation and Consultation Service for assistance with the strength testing. 1 Reviewed and Approved by

  18. A Cryogenic RF Material Testing Facility at SLAC

    Energy Technology Data Exchange (ETDEWEB)

    Guo, Jiquan; Martin, David; Tantawi, Sami; Yoneda, Charles; /SLAC

    2012-06-22

    The authors have developed an X-band SRF testing system using a high-Q copper cavity with an interchangeable flat bottom for the testing of different materials. By measuring the Q of the cavity, the system is capable to characterize the quenching magnetic field of the superconducting samples at different power level and temperature, as well as the surface resistivity. This paper presents the most recent development of the system and testing results.

  19. New JMTR irradiation test plan on fuels and materials

    International Nuclear Information System (INIS)

    Nakamura, Takehiko; Nishiyama, Yutaka; Chimi, Yasuhiro; Sasajima, Hideo; Ogiyanagi, Jin; Nakamura, Jinichi; Suzuki, Masahide; Kawamura, Hiroshi

    2009-01-01

    In order to maintain and enhance safety of light water reactors (LWRs) in long-term and up-graded operations, proper understanding of irradiation behavior of fuels and materials is essentially important. Japanese government and the Japan Atomic Energy Agency (JAEA) have decided to refurbish the Japan Materials Testing Reactor (JMTR) and to install new tests rigs, in order to play an active role for solving irradiation related issues on plant aging and high-duty uses of the current LWRs and on development of next-generation reactors. New tests on fuel integrity under simulated abnormal transients and high-duty irradiation conditions are planned in the JMTR. Power ramp tests of newdesign fuel rods will also be performed in the first stage of the program, which is expected to start in year 2011 after refurbishment of the JMTR. Combination of the JMTR tests with simulated reactivity initiated accident tests in the Nuclear Safety Research Reactor (NSRR) and loss of coolant accident tests in hot laboratories would serve as the integrated fuel safety research on the high performance fuels at extended burnups, covering from the normal to the accident conditions, including abnormal transients. For the materials irradiation, fracture toughness of reactor vessel steels and stress corrosion cracking behavior of stainless steels are being studied in addition to basic irradiation behavior of nuclear materials such as hafnium. The irradiation studies would contribute not only to solve the current problems but also to identify possible seeds of troubles and to make proactive responses. (author)

  20. Standard Test Method for Contamination Outgassing Characteristics of Spacecraft Materials

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2009-01-01

    1.1 This test method covers a technique for generating data to characterize the kinetics of the release of outgassing products from materials. This technique will determine both the total mass flux evolved by a material when exposed to a vacuum environment and the deposition of this flux on surfaces held at various specified temperatures. 1.2 This test method describes the test apparatus and related operating procedures for evaluating the total mass flux that is evolved from a material being subjected to temperatures that are between 298 and 398 K. Pressures external to the sample effusion cell are less than 7 × 10−3 Pa (5 × 10−5 torr). Deposition rates are measured during material outgassing tests. A test procedure for collecting data and a test method for processing and presenting the collected data are included. 1.3 This test method can be used to produce the data necessary to support mathematical models used for the prediction of molecular contaminant generation, migration, and deposition. 1.4 Al...

  1. Ultraviolet Testing of Space Suit Materials for Mars

    Science.gov (United States)

    Larson, Kristine; Fries, Marc

    2017-01-01

    Human missions to Mars may require radical changes in the approach to extra-vehicular (EVA) suit design. A major challenge is the balance of building a suit robust enough to complete multiple EVAs under intense ultraviolet (UV) light exposure without losing mechanical strength or compromising the suit's mobility. To study how the materials degrade on Mars in-situ, the Jet Propulsion Laboratory (JPL) invited the Advanced Space Suit team at NASA's Johnson Space Center (JSC) to place space suit materials on the Scanning Habitable Environments with Raman & Luminescence for Organics and Chemicals (SHERLOC) instrument's calibration target of the Mars 2020 rover. In order to select materials for the rover and understand the effects from Mars equivalent UV exposure, JSC conducted ground testing on both current and new space suit materials when exposed to 2500 hours of Mars mission equivalent UV. To complete this testing, JSC partnered with NASA's Marshall Space Flight Center to utilize their UV vacuum chambers. Materials tested were Orthofabric, polycarbonate, Teflon, Dacron, Vectran, spectra, bladder, nGimat coated Teflon, and nGimat coated Orthofabric. All samples were measured for mass, tensile strength, and chemical composition before and after radiation. Mass loss was insignificant (less than 0.5%) among the materials. Most materials loss tensile strength after radiation and became more brittle with a loss of elongation. Changes in chemical composition were seen in all radiated materials through Spectral Analysis. Results from this testing helped select the materials that will fly on the Mars 2020 rover. In addition, JSC can use this data to create a correlation to the chemical changes after radiation-which is what the rover will send back while on Mars-to the mechanical changes, such as tensile strength.

  2. Development of Standardized Material Testing Protocols for Prosthetic Liners.

    Science.gov (United States)

    Cagle, John C; Reinhall, Per G; Hafner, Brian J; Sanders, Joan E

    2017-04-01

    A set of protocols was created to characterize prosthetic liners across six clinically relevant material properties. Properties included compressive elasticity, shear elasticity, tensile elasticity, volumetric elasticity, coefficient of friction (CoF), and thermal conductivity. Eighteen prosthetic liners representing the diverse range of commercial products were evaluated to create test procedures that maximized repeatability, minimized error, and provided clinically meaningful results. Shear and tensile elasticity test designs were augmented with finite element analysis (FEA) to optimize specimen geometries. Results showed that because of the wide range of available liner products, the compressive elasticity and tensile elasticity tests required two test maxima; samples were tested until they met either a strain-based or a stress-based maximum, whichever was reached first. The shear and tensile elasticity tests required that no cyclic conditioning be conducted because of limited endurance of the mounting adhesive with some liner materials. The coefficient of friction test was based on dynamic coefficient of friction, as it proved to be a more reliable measurement than static coefficient of friction. The volumetric elasticity test required that air be released beneath samples in the test chamber before testing. The thermal conductivity test best reflected the clinical environment when thermal grease was omitted and when liner samples were placed under pressure consistent with load bearing conditions. The developed procedures provide a standardized approach for evaluating liner products in the prosthetics industry. Test results can be used to improve clinical selection of liners for individual patients and guide development of new liner products.

  3. Radioactive material package testing capabilities at Sandia National Laboratories

    International Nuclear Information System (INIS)

    Uncapher, W.L.; Hohnstreiter, G.F.

    1995-01-01

    Evaluation and certification of radioactive and hazardous material transport packages can be accomplished by subjecting these packages to normal transport and hypothetical accident test conditions. The regulations allow package designers to certify packages using analysis, testing, or a combination of analysis and testing. Testing can be used to substantiate assumptions used in analytical models and to demonstrate package structural and thermal response. Regulatory test conditions include impact, puncture, crush, penetration, water spray, immersion, and thermal environments. Testing facilities are used to simulate the required test conditions and provide measurement response data. Over the past four decades, comprehensive testing facilities have been developed at Sandia National Laboratories to perform a broad range of verification and certification tests on hazardous and radioactive material packages or component sections. Sandia's facilities provide an experience base that has been established during the development and certification of many package designs. These unique facilities, along with innovative instrumentation data collection capabilities and techniques, simulate a broad range of testing environments. In certain package designs, package testing can be an economical alternative to complex analysis to resolve regulatory questions or concerns

  4. Report of the 2nd RCM on nanoscale radiation engineering of advanced materials for potential biomedical applications

    International Nuclear Information System (INIS)

    2010-01-01

    There are critical needs for advanced materials in the area of biomaterial engineering, primarily in generating biomaterials of enhanced specific functionalities, improved biocompatibility, and minimal natural rejection but with enhanced interfacial adhesion. These can be achieved by introduction of proper functionalities at the nanoscale dimensions for which, due to their characteristics, radiation techniques are uniquely suited. Accordingly, many of the IAEA Member States (MS) have interest in creating advanced materials for various health-care applications using a wide array of radiation sources and their broad expertise. In seeking new knowledge to advance the field and tackle this specific problem, to collaborate to enhance the quality of the scientific research and improve their efficiency and effectiveness, MS had requested the support of the IAEA for such collaboration. Based on these requests, and the conclusions and recommendations of the Consultant's meeting on Advanced Materials on the Nano-scale Synthesized by Radiation-Induced Processes, held on 10-14 December 2007, the present CRP was formulated and started in 2009. The first RCM was held in 30 March – 3 April 2009, in Vienna, where the work plan for both individual participants and collaborations were discussed and accepted, as reported in the Meeting Report published as IAEA Working Material (http://www-naweb.iaea.org/napc/iachem/working_materials.html). The second RCM was held on 15-19 November 2010, Paris, France, and was attended by 17 participants (chief scientific investigators or team members) and one cost-free observer from Brazil. The participants presented their research achievements since the first RCM, centred on the main expected outputs of this CRP: a. Methodologies to prepare and characterize nanogels; nanoparticles and nanoporous membranes, as well as to synthesize and modify nanoparticle surfaces by attaching organic ligands by radiation; b. Methodologies to radiation synthesize

  5. METHOD OF TESTING THERMAL NEUTRON FISSIONABLE MATERIAL FOR PURITY

    Science.gov (United States)

    Fermi, E.; Anderson, H.L.

    1961-01-24

    A process is given for determining the neutronic purity of fissionable material by the so-called shotgun test. The effect of a standard neutron absorber of known characteristics and amounts on a neutronic field also of known characteristics is measured and compared with the effect which the impurities derived from a known quantity of fissionable material has on the same neutronic field. The two readings are then made the basis of calculation from which the amount of impurities can be computed.

  6. Erosion tests of materials by energetic particle beams

    International Nuclear Information System (INIS)

    Schechter, D.E.; Tsai, C.C.; Sluss, F.; Becraft, W.R.; Hoffman, D.J.

    1985-01-01

    The internal components of magnetic fusion devices must withstand erosion from and high heat flux of energetic plasma particles. The selection of materials for the construction of these components is important to minimize contamination of the plasma. In order to study various materials' comparative resistance to erosion by energetic particles and their ability to withstand high heat flux, water-cooled copper swirl tubes coated or armored with various materials were subjected to bombardment by hydrogen and helium particle beams. Materials tested were graphite, titanium carbide (TiC), chromium, nickel, copper, silver, gold, and aluminum. Details of the experimental arrangement and methods of application or attachment of the materials to the copper swirl tubes are presented. Results including survivability and mass losses are discussed

  7. Assessing the Rebound Hammer Test for Rammed Earth Material

    Directory of Open Access Journals (Sweden)

    Quoc-Bao Bui

    2017-10-01

    Full Text Available Rammed-earth (RE is a construction material manufactured from the soil. The soil is compacted at its optimum water content, inside a formwork to build a monolithic wall. RE material is attracting renewed interest throughout the world thanks to its sustainable characteristics: low embodied energy, substantial thermal inertia, and natural regulator of moisture; on the other hand, the existing historic RE buildings is still numerous. This is why several research studies have been carried out recently to study different aspects of this material. However, few investigations have been carried out to explore the possibility of applying the nondestructive techniques on RE walls. This paper presents an assessment of the well-known rebound hammer test on RE walls. The calibration curves of the rebound hammer test have been established for conventional concrete where the rebound number is more than 20. For RE material with lower compressive strengths, a new calibration curve must be established. In the present study, two soils were used and different homogenized specimens with different dry densities were manufactured and tested, to plot a general calibration curve. Then, this calibration curve was applied to RE specimens; different results at different positions in an earthen layer were observed, due to the inhomogeneity of the material. The final results showed an acceptable accuracy of the calibration curve in the prediction of the compressive strength of RE material.

  8. Capsule irradiation tests of non-fissile materials in HANARO

    International Nuclear Information System (INIS)

    Choo, K. N.; Sohn, J. M.; Kim, B. G.; Shin, Y. T.; Oh, J. M.; Lim, I. C.; Kang, Y. H.

    2003-01-01

    The R and D programs on the nuclear reactor materials require numerous in-pile tests in HANARO. Extensive efforts have been made to establish design and manufacturing technology for the development of irradiation facilities. Material capsule and rabbit(small non-instrumented capsule) systems were developed for the irradiation test of non fissile materials in HANARO. Several irradiation capsules (8 instrumented and 2 non-instrumented capsules) and rabbits(17 rabbits) has been designed, fabricated and successfully irradiated in HANARO CT, IR, HTS or IP test holes since 1995. Capsules were designed for the irradiation of RPV (Reactor Pressure Vessel), reactor core materials, and Zr-based alloys. Most capsules were made for KAERI material research projects, but 3 capsules were made as a part of national projects for the promotion of HANARO utilization. Rabbits were used for the irradiation of semi-conductors(Si, Sapphire) and magnetic materials. 3,300 specimens from domestic 13 research institutes, 2 nuclear industry companies and 51 universities, were irradiated in HANARO for 26,000 hours using capsule and rabbit irradiation systems. Through this research, the nuclear characteristics of HANARO capsules and rabbits were also produced and piled up in our database

  9. Limit analysis, rammed earth material and Casagrande test

    Science.gov (United States)

    El-Nabouch, Ranime; Pastor, Joseph; Bui, Quoc-Bao; Plé, Olivier

    2018-02-01

    The present paper is concerned with the simulation of the Casagrande test carried out on a rammed earth material for wall-type structures in the framework of Limit Analysis (LA). In a preliminary study, the material is considered as a homogeneous Coulomb material, and existing LA static and kinematic codes are used for the simulation of the test. In each loading case, static and kinematic bounds coincide; the corresponding exact solution is a two-rigid-block mechanism together with a quasi-constant stress vector and a velocity jump also constant along the interface, for the three loading cases. In a second study, to take into account the influence of compressive loadings related to the porosity of the material, an elliptic criterion (denoted Cohesive Cam-Clay, CCC) is defined based on recent homogenization results about the hollow sphere model for porous Coulomb materials. Finally, original finite element formulations of the static and mixed kinematic methods for the CCC material are developed and applied to the Casagrande test. The results are the same than above, except that this time the velocity jump depends on the compressive loading, which is more realistic but not satisfying fully the experimental observations. Therefore, the possible extensions of this work towards non-standard direct methods are analyzed in the conclusion section.

  10. Capsule Development and Utilization for Material Irradiation Tests

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Bong Goo; Kang, Y. H.; Cho, M. S. (and others)

    2007-06-15

    The essential technology for an irradiation test of materials and nuclear fuel has been successively developed and utilized to meet the user's requirements in Phase I(July 21, 1997 to March 31, 2000). It enables irradiation tests to be performed for a non-fissile material under a temperature control(300{+-}10 .deg. C) in a He gas environment, and most of the irradiation tests for the internal and external users are able to be conducted effectively. The basic technology was established to irradiate a nuclear fuel, and a creep capsule was also developed to measure the creep property of a material during an irradiation test in HANARO in Phase II(April 1, 2000 to March 31, 2003). The development of a specific purpose capsule, essential technology for a re-irradiation of a nuclear fuel, advanced technology for an irradiation of materials and a nuclear fuel were performed in Phase III(April 1, 2003 to February 28, 2007). Therefore, the technology for an irradiation test was established to support the irradiation of materials and a nuclear fuel which is required for the National Nuclear R and D Programs. In addition, an improvement of the existing capsule design and fabrication technology, and the development of an instrumented capsule for a nuclear fuel and a specific purpose will be able to satisfy the user's requirements. In order to support the irradiation test of materials and a nuclear fuel for developing the next generation nuclear system, it is also necessary to continuously improve the design and fabrication technology of the existing capsule and the irradiation technology.

  11. DOE/MSU composite material fatigue database: Test methods, materials, and analysis

    Energy Technology Data Exchange (ETDEWEB)

    Mandell, J.F.; Samborsky, D.D. [Montana State Univ., Bozeman, MT (United States). Dept. of Chemical Engineering

    1997-12-01

    This report presents a detailed analysis of the results from fatigue studies of wind turbine blade composite materials carried out at Montana State University (MSU) over the last seven years. It is intended to be used in conjunction with the DOE/MSU composite Materials Fatigue Database. The fatigue testing of composite materials requires the adaptation of standard test methods to the particular composite structure of concern. The stranded fabric E-glass reinforcement used by many blade manufacturers has required the development of several test modifications to obtain valid test data for materials with particular reinforcement details, over the required range of tensile and compressive loadings. Additionally, a novel testing approach to high frequency (100 Hz) testing for high cycle fatigue using minicoupons has been developed and validated. The database for standard coupon tests now includes over 4,100 data points for over 110 materials systems. The report analyzes the database for trends and transitions in static and fatigue behavior with various materials parameters. Parameters explored are reinforcement fabric architecture, fiber content, content of fibers oriented in the load direction, matrix material, and loading parameters (tension, compression, and reversed loading). Significant transitions from good fatigue resistance to poor fatigue resistance are evident in the range of materials currently used in many blades. A preliminary evaluation of knockdowns for selected structural details is also presented. The high frequency database provides a significant set of data for various loading conditions in the longitudinal and transverse directions of unidirectional composites out to 10{sup 8} cycles. The results are expressed in stress and strain based Goodman Diagrams suitable for design. A discussion is provided to guide the user of the database in its application to blade design.

  12. Integrated Biomaterials for Biomedical Technology

    CERN Document Server

    Ramalingam, Murugan; Ramakrishna, Seeram; Kobayashi, Hisatoshi

    2012-01-01

    This cutting edge book provides all the important aspects dealing with the basic science involved in materials in biomedical technology, especially structure and properties, techniques and technological innovations in material processing and characterizations, as well as the applications. The volume consists of 12 chapters written by acknowledged experts of the biomaterials field and covers a wide range of topics and applications.

  13. Compilation of radiation damage test data cable insulating materials

    CERN Document Server

    Schönbacher, H; CERN. Geneva

    1979-01-01

    This report summarizes radiation damage test data on commercially available organic cable insulation and jacket materials: ethylene- propylene rubber, Hypalon, neoprene rubber, polyethylene, polyurethane, polyvinylchloride, silicone rubber, etc. The materials have been irradiated in a nuclear reactor to integrated absorbed doses from 5*10/sup 5/ to 5*10/sup 6/ Gy. Mechanical properties, e.g. tensile strength, elongation at break, and hardness, have been tested on irradiated and non-irradiated samples. The results are presented in the form of tables and graphs, to show the effect of the absorbed dose on the measured properties. (13 refs).

  14. Standard test methods for rockwell hardness of metallic materials

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2008-01-01

    1.1 These test methods cover the determination of the Rockwell hardness and the Rockwell superficial hardness of metallic materials by the Rockwell indentation hardness principle. This standard provides the requirements for Rockwell hardness machines and the procedures for performing Rockwell hardness tests. 1.2 This standard includes additional requirements in annexes: Verification of Rockwell Hardness Testing Machines Annex A1 Rockwell Hardness Standardizing Machines Annex A2 Standardization of Rockwell Indenters Annex A3 Standardization of Rockwell Hardness Test Blocks Annex A4 Guidelines for Determining the Minimum Thickness of a Test Piece Annex A5 Hardness Value Corrections When Testing on Convex Cylindrical Surfaces Annex A6 1.3 This standard includes nonmandatory information in appendixes which relates to the Rockwell hardness test. List of ASTM Standards Giving Hardness Values Corresponding to Tensile Strength Appendix X1 Examples of Procedures for Determining Rockwell Hardness Uncertainty Appendix X...

  15. Standard test methods for rockwell hardness of metallic materials

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2011-01-01

    1.1 These test methods cover the determination of the Rockwell hardness and the Rockwell superficial hardness of metallic materials by the Rockwell indentation hardness principle. This standard provides the requirements for Rockwell hardness machines and the procedures for performing Rockwell hardness tests. 1.2 This standard includes additional requirements in annexes: Verification of Rockwell Hardness Testing Machines Annex A1 Rockwell Hardness Standardizing Machines Annex A2 Standardization of Rockwell Indenters Annex A3 Standardization of Rockwell Hardness Test Blocks Annex A4 Guidelines for Determining the Minimum Thickness of a Test Piece Annex A5 Hardness Value Corrections When Testing on Convex Cylindrical Surfaces Annex A6 1.3 This standard includes nonmandatory information in appendixes which relates to the Rockwell hardness test. List of ASTM Standards Giving Hardness Values Corresponding to Tensile Strength Appendix X1 Examples of Procedures for Determining Rockwell Hardness Uncertainty Appendix X...

  16. Study of the chain microstructure effects on the resulting thermal properties of poly(L-lactide)/poly(N-isopropylacrylamide) biomedical materials

    Energy Technology Data Exchange (ETDEWEB)

    Lizundia, E., E-mail: erlantz.liizundia@ehu.es [Macromolecular Chemistry Research Group (LABQUIMAC), Dept. of Physical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU) (Spain); Meaurio, E., E-mail: emiliano.meaurio@ehu.es [Department of Mining-Metallurgy and Materials Science and BERC POLYMAT, School of Engineering, University of the Basque Country (UPV/EHU) (Spain); Laza, J.M., E-mail: josemanuel.laza@ehu.es [Macromolecular Chemistry Research Group (LABQUIMAC), Dept. of Physical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU) (Spain); Vilas, J.L., E-mail: joseluis.vilas@bcmaterials.net [Basque Center for Materials, Applications and Nanostructures (BCMaterials), Parque Tecnológico de Bizkaia, Ed. 500, Derio 48160 (Spain); León Isidro, L.M., E-mail: luismanuel.leon@ehu.es [Macromolecular Chemistry Research Group (LABQUIMAC), Dept. of Physical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU) (Spain); Basque Center for Materials, Applications and Nanostructures (BCMaterials), Parque Tecnológico de Bizkaia, Ed. 500, Derio 48160 (Spain)

    2015-05-01

    The development of thermally-sensitive poly(N-isopropylacrylamide) (PNIPAAm) and biocompatible/biodegradable poly(L-lactide) (PLLA) blends offers us an efficient strategy in order to obtain materials with improved functional properties to be used in the emerging field of biomedicine. In this sense, thermal properties of PLLA and PNIPAAm have been investigated by differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA). Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM) and wide angle X-ray diffraction (WAXD) were conducted to shed more light on the obtained results. For a better understanding of PLLA/PNIPAAm system, both low and high molecular weight PLLA and PNIPAAm have been synthesized by ring opening polymerization and aqueous redox polymerization respectively. Obtained results are interpreted from the viewpoint of chain microstructure of each homopolymer and the ratio between two constituent materials. DSC, SEM and WAXD results show a phase separation over the entire composition range irrespectively of the molecular weight of both homopolymers. Additionally, it was found a nucleating agent behavior of low molecular weight PNIPAAm, while high molecular weight PNIPAAm hinders the crystallization of PLLA. FTIR results suggest that the strong autoassociation present in PNIPAAm plays a key role impairing the miscibility of the whole system. Thermogravimetric analysis reveals that thermodegradation process of PLLA could be continuously delayed with the addition of PNIPAAm due to the increased thermal stability of N-isopropylacrylamide in regard to L-lactide sequences. - Highlights: • Poly(L-lactide)/poly(N-isopropylacrylamide) biomedical materials are synthesized. • Results are interpreted in terms of the building block nature of each constituent. • Phase separation behavior over the entire composition range is achieved. • Strong autoassociation present in PNIPAAm impairs the miscibility of the whole blend

  17. Scoping Future Policy Dynamics in Raw Materials Through Scenarios Testing

    Science.gov (United States)

    Correia, Vitor; Keane, Christopher; Sturm, Flavius; Schimpf, Sven; Bodo, Balazs

    2017-04-01

    The International Raw Materials Observatory (INTRAW) project is working towards a sustainable future for the European Union in access to raw materials, from an availability, economical, and environmental framework. One of the major exercises for the INTRAW project is the evaluation of potential future scenarios for 2050 to frame economic, research, and environmental policy towards a sustainable raw materials supply. The INTRAW consortium developed three possible future scenarios that encompass defined regimes of political, economic, and technological norms. The first scenario, "Unlimited Trade," reflects a world in which free trade continues to dominate the global political and economic environment, with expectations of a growing demand for raw materials from widely distributed global growth. The "National Walls" scenario reflects a world where nationalism and economic protectionism begins to dominate, leading to stagnating economic growth and uneven dynamics in raw materials supply and demand. The final scenario, "Sustainability Alliance," examines the dynamics of a global political and economic climate that is focused on environmental and economic sustainability, leading towards increasingly towards a circular raw materials economy. These scenarios were reviewed, tested, and provided simulations of impacts with members of the Consortium and a panel of global experts on international raw materials issues which led to expected end conditions for 2050. Given the current uncertainty in global politics, these scenarios are informative to identifying likely opportunities and crises. The details of these simulations and expected responses to the research demand, technology investments, and economic components of raw materials system will be discussed.

  18. Flight simulation testing equipment for composite material systems

    Science.gov (United States)

    Haskins, J. F.; Wilkins, D. J.; Stein, B. A.

    1976-01-01

    A test program is discussed which aims at establishing the time-temperature-stress characteristics of several classes of high-temperature composite materials in order to determine their suitability for applications in supersonic cruise aircraft. Five advanced composite materials (a boron epoxy, a boron polyimide, a graphite epoxy, a graphite polyimide, and diffusion-bonded boron aluminum) are being evaluated using a flight-test simulator capable of long-term automatic testing based on random loading and realistic flight temperature profiles. The design, construction, and checkout of this simulator are described along with the digital load programmer, load magnitude controllers, the hydraulic pumping system, the heating and cooling systems, the control console, and the data recording system. Typical results for short-term tests performed at constant temperatures and accelerated load rates are presented in terms of a random-load spectrum and a wearout model.

  19. Numerical regulation of a test facility of materials for PWR

    International Nuclear Information System (INIS)

    Zauq, M.H.

    1982-02-01

    The installation aims at testing materials used in nuclear power plants; tests consists in simulations of a design basis accident (failure of a primary circuit of a PWR type reactor) for a qualification of these materials. A description of the test installation, of the thermodynamic control, and of the control system is presented. The organisation of the software is then given: description of the sequence chaining monitor, operation, list and function of the programs. The analog information processing is also presented (data transmission). A real-time microcomputer and clock are used for this work. The microprocessor is the 6800 of MOTOROLA. The microcomputer used has been built around the MC 6800; its structure is described. The data acquisition include an analog data acquisition system and a numerical data acquisition system. Laboratory and on-site tests are finally presented [fr

  20. Chemical, biomedical and ecological studies of SRC-I materials from the Fort Lewis Pilot Plant: a status report

    Energy Technology Data Exchange (ETDEWEB)

    Mahlum, D.D. (ed.)

    1981-01-01

    This document discusses studies performed with solvent refined coal (SRC) materials obtained from the Fort Lewis Pilot Plant during operation in the SRC-I mode. The development of analytical methodology is presented as well as results obtained from the application of these methods to light oil (LO), wash solvent (WS) and process solvent (PS). Results of cellular and animal studies with LO, WS and PS are included, along with a description of methods for the generation and characterization of LO and PS aerosols, and for exposing rats, mice and guinea pigs to these aerosols. The effects of SRC-I product on seed germination and plant growth which have also been studied are discussed. The SRC-I product, feed coal and the mineral residue have been analyzed for organic and inorganic constituents. The higher-boiling-point material, PS, exhibited significant mutagenic activity in the Ames assay; LO and WS were inactive. Process solvent also caused transformation of cultured Syrian hamster embryo cells. Additional chemical fractionation studies suggest that primary aromatic amines are major determinants of the observed mutagenic activity. Skin-painting studies with SRC-II naphtha, heavy distillate, shale oil and petroleum crude indicate a good correlation between the results of the cellular assays and skin carcinogenesis in mice. Wash solvent was more toxic after oral administration to rats than was light oil or process solvent. The effects of LO, WS and PS on development were studied after administration to pregnant rats. The tissue distribution of a number of components of PS was studied after oral administration of PS to rats. The effect of SRC-I product on the germination and growth of barley was investigated by mixing or layering the product with soil and placing the mixture in a field lysimeter.

  1. Use of laser extensometer for mechanical test on irradiated materials

    Energy Technology Data Exchange (ETDEWEB)

    Brillaud, C.; Meylogan, T.; Salathe, P. [Electricite de France, Avoine (France)

    1996-12-31

    Techniques have been developed by EDF`s hot laboratory in Chinon for performing mechanical tests on irradiated materials. Some of these techniques aim to facilitate strain measurements, which are particularly difficult to perform on irradiated specimens at high temperatures or on subsize specimens. Recent progress has been driven by laser technology combined with software development. The use of this technique, which allows strain measurements without contact on the specimen, is described for tensile (especially on subsize specimens), fatigue and creep tests.

  2. Impact Testing of Orbiter Thermal Protection System Materials

    Science.gov (United States)

    Kerr, Justin

    2006-01-01

    This viewgraph presentation reviews the impact testing of the materials used in designing the shuttle orbiter thermal protection system (TPS). Pursuant to the Columbia Accident Investigation Board recommendations a testing program of the TPS system was instituted. This involved using various types of impactors in different sizes shot from various sizes and strengths guns to impact the TPS tiles and the Leading Edge Structural Subsystem (LESS). The observed damage is shown, and the resultant lessons learned are reviewed.

  3. Capsule Development and Utilization for Material Irradiation Tests

    International Nuclear Information System (INIS)

    Kang, Young Hwan; Kim, B. G.; Joo, K. N.

    2003-05-01

    The objective of this project was to establish basic capsule irradiation technology using the multi-purpose research reactor [HANARO] to eventually support national R and D projects of advanced fuel and materials related to domestic nuclear power plants and next generation reactors. There are several national nuclear projects in KAERI, which require several irradiation tests to investigate in-pile behavior of nuclear reactor fuel and materials for the R and D of several types of fuels such as advanced PWR and DUPIC fuels and for the R and D of structural materials such as RPV(reactor pressure vessel) steel, Inconel, zirconium alloy, and stainless steel. At the moment, internal and external researchers in institutes, industries and universities are interested in investigating the irradiation characteristics of materials using the irradiation facilities of HANARO. For these kinds of material irradiation tests, it is important to develop various capsules using our own techniques. The development of capsules requires several leading-edge technologies and our own experiences related to design and fabrication. In the second phase from April 1,2000 to March 31, 2003, the utilization technologies were developed using various sensors for the measurements of temperature, pressure and displacement, and instrumented capsule technologies for the required fuel irradiation tests were developed. In addition, the improvement of the existing capsule technologies and the development of an in-situ measurable creep capsule for specific purposes were done to meet the various requirements of users

  4. The addition of Si to the Ti–35Nb alloy and its effect on the corrosion resistance, when applied to biomedical materials

    Energy Technology Data Exchange (ETDEWEB)

    Tavares, A.M.G.; Fernandes, B.S.; Souza, S.A.; Batista, W.W.; Cunha, F.G.C. [Department of Materials Science and Engineering, Federal University of Sergipe, 49100-000 São Cristóvão, SE (Brazil); Landers, R. [Institute of Physics Gleb Wataghin, State University of Campinas – UNICAMP, 13083-859 Campinas, SP (Brazil); Macedo, M.C.S.S., E-mail: michellecardinales@gmail.com [Department of Materials Science and Engineering, Federal University of Sergipe, 49100-000 São Cristóvão, SE (Brazil)

    2014-04-05

    Highlights: • An investigation of the corrosion resistance of Ti–Nb–Si was proposed. • The study was based on polarization curves, OCP, electrochemical impedance, XPS. • The addition of Si to 0.35% increased the corrosion resistance of the alloys. • Data suggest that the studied alloys are promising for biomedical applications. -- Abstract: Alloy elements such as niobium and silicon have been added to titanium as an alternative for new materials to be used in orthopedic implants once they present biocompatibility and favor reductions in the elastic modulus. However, these new materials’ behavior, in face of corrosion is still demanding careful investigations because they will be subjected to an aggressive environ, such as the human body. The corrosion resistance of the Ti–35Nb–(0; 0.15; 0.35; 0.55)Si (% in mass) when in physiological medium was assessed by means of polarization curves, open circuit potential and electrochemical impedance spectroscopy. The compositions of the passive films were analyzed by X-ray photoelectron spectroscopy (XPS). Outcomes show that the alloys presented good rapid repassivation capacity after film breaking under high potentials. The high values of resistance to polarization – Rp – pinpoint that the formed oxide films are resistive. They work as a protecting barrier against aggressive ions. Data suggest that the studied alloys are promising for orthopedic implant applications.

  5. Effects of cross-linking on mechanical, biological properties and biodegradation behavior of Nile tilapia skin collagen sponge as a biomedical material.

    Science.gov (United States)

    Sun, Leilei; Li, Bafang; Yao, Di; Song, Wenkui; Hou, Hu

    2018-04-01

    The objective of this study was to explore the effects of dehydrothermal treatment (DHT) and glutaraldehyde (GTA) cross-linking on mechanical, biological properties and biodegradation behavior of Nile tilapia skin collagen sponge fabricated by freeze-drying technology. It was found that the GTA cross-linked collagen sponge exhibited a higher degree of cross-linking in comparison with DHT. The extent of increased tensile strength as well as hygroscopicity indicated that GTA cross-linking was superior to DHT in mechanical properties and liquid absorption, which was attributed to different cross-linking mechanisms. Hygroscopicity assay indicated that cross-linking could improve stability of collagen in solutions. No obvious changes in porosity and blood coagulation time were observed whether cross-linking or not. Results from collagenase biodegradation assay in vitro illustrated that GTA-treated collagen sponge was more resistant to collagenase biodegradation, while DHT exhibited negligible resistance. In addition, photochemical stability of collagen sponge was studied by Fourier transforms infrared spectroscopy (FTIR), which indicated that both cross-linking treatments could not change the backbone structure of collagen. Furthermore, the microstructure of collagen sponge was stable after cross-linking. The highly porous and interconnected structure of collagen sponge was helpful to the absorption of wound exudates, supplement of oxygen and cell proliferation, accompanied with good blood compatibility, which indicated that our fabricated collagen sponge could be applied in biomedical materials field as wound dressings. Copyright © 2018. Published by Elsevier Ltd.

  6. Using in situ nanocellulose-coating technology based on dynamic bacterial cultures for upgrading conventional biomedical materials and reinforcing nanocellulose hydrogels.

    Science.gov (United States)

    Zhang, Peng; Chen, Lin; Zhang, Qingsong; Jönsson, Leif J; Hong, Feng F

    2016-07-08

    Bacterial nanocellulose (BNC) is a microbial nanofibrillar hydrogel with many potential applications. Its use is largely restricted by insufficient strength when in a highly swollen state and by inefficient production using static cultivation. In this study, an in situ nanocellulose-coating technology created a fabric-frame reinforced nanocomposite of BNC hydrogel with superior strength but retained BNC native attributes. By using the proposed technology, production time could be reduced from 10 to 3 days to obtain a desirable hydrogel sheet with approximately the same thickness. This novel technology is easier to scale up and is more suitable for industrial-scale manufacture. The mechanical properties (tensile strength, suture retention strength) and gel characteristics (water holding, absorption and wicking ability) of the fabric-reinforced BNC hydrogel were investigated and compared with those of ordinary BNC hydrogel sheets. The results reveal that the fabric-reinforced BNC hydrogel was equivalent with regard to gel characteristics, and exhibited a qualitative improvement with regard to its mechanical properties. For more advanced applications, coating technology via dynamic bacterial cultures could be used to upgrade conventional biomedical fabrics, i.e. medical cotton gauze or other mesh materials, with nanocellulose. © 2016 American Institute of Chemical Engineers Biotechnol. Prog., 32:1077-1084, 2016. © 2016 American Institute of Chemical Engineers.

  7. Numerical test on polystyrene tunnel seismic-isolation material

    Directory of Open Access Journals (Sweden)

    He Jianping

    2016-09-01

    Full Text Available Stress-strain mechanical properties of polystyrene foam plastic material were tested under different loading conditions. An empirical constitutive model for describing metal materials was proposed for the polystyrene plastic foam. The static and dynamic tests results show that the ductility and watertightness of the polystyrene plastic foam are significantly improved. At the same time, in order to check its seismic-isolation property, the high-performance foam concrete as filling materials of Galongla tunnel in Tibet was simulated by FEM. The simulated results show that the polystyrene plastic foam can remarkably decrease the stress and the plastic zone in final lining, so it can effectively reduce the seismic damage of the tunnel. Considering the seismic-isolation property and low price of polystyrene plastic foam, it is a good reference for the anti-seismic design of tunnels in high intensity zones.

  8. Multilayer Pressure Vessel Materials Testing and Analysis. Phase 1

    Science.gov (United States)

    Cardinal, Joseph W.; Popelar, Carl F.; Page, Richard A.

    2014-01-01

    To provide NASA a comprehensive suite of materials strength, fracture toughness and crack growth rate test results for use in remaining life calculations for aging multilayer pressure vessels, Southwest Research Institute (R) (SwRI) was contracted in two phases to obtain relevant material property data from a representative vessel. This report describes Phase 1 of this effort which includes a preliminary material property assessment as well as a fractographic, fracture mechanics and fatigue crack growth analyses of an induced flaw in the outer shell of a representative multilayer vessel that was subjected to cyclic pressure test. SwRI performed this Phase 1 effort under contract to the Digital Wave Corporation in support of their contract to Jacobs ATOM for the NASA Ames Research Center.

  9. Introduction to non-destructive testing of materials: part II

    International Nuclear Information System (INIS)

    Ahmed, M.; Ahmed, B.

    2001-01-01

    Ultrasonic waves are mechanical vibrations that require a medium, which functions as carrier. Ultrasonics are widely used in non-destructive testing of materials in which high frequency sound waves are introduced into the material being inspected. If the frequency of sound waves in within the range 10 to 20,000 Hz, the sound is audible, i.e. the range of hearing, above 20,000 Hz, the sound waves are referred to as Ultrasound or Ultrasonics. Sound waves do not cause any permanent change in material although its transient presence is very noticeable. An energy transport through a sound wave is possible only when constituent particles are connected to each other by elastic forces. Liquids and Gases are also suitable media for the transmission of sound. In vacuum no matter exists and thus no sound transmission is possible. At the end of this article advantages and limitations of ultrasonic testing are also given. (A.B.)

  10. The Testing Effect Is Alive and Well with Complex Materials

    Science.gov (United States)

    Karpicke, Jeffrey D.; Aue, William R.

    2015-01-01

    Van Gog and Sweller (2015) claim that there is no testing effect--no benefit of practicing retrieval--for complex materials. We show that this claim is incorrect on several grounds. First, Van Gog and Sweller's idea of "element interactivity" is not defined in a quantitative, measurable way. As a consequence, the idea is applied…

  11. Fusion materials irradiation test facility: description and status

    International Nuclear Information System (INIS)

    Trego, A.L.; Parker, E.F.; Hagan, J.W.

    1982-01-01

    The Fusion Materials Irradiation Test (FMIT) Facility will generate a high-flux, high-energy neutron source that will provide a fusion-like radiation environment for fusion reactor materials development. The neutrons will be produced in a nuclear stripping reaction by impinging a 35 MeV beam of deuterons from an Alvarez-type linear accelerator on a flowing lithium target. The target will be located in a test cell which will provide an irradiation volume of over 750l within which 10 cm 3 will have an average neutron flux of greater than 1.4 x 10 15 n/cm 2 -s and 500 cm 3 an average flux of greater than 2.2 by 10 14 n/cm 2- s with an expected availability factor greater than 65%. The projected fluence within the 10 cm 3 high flux region of FMIT will effect damage upon the materials test specimens to 30 dpa (displacements per atom) for each 90 day irradiation period. This irradiation flux volume will be at least 500 times larger than that of any other facility with comparable neutron energy and will fully meet the fusion materials damage research objective of 100 dpa within three years for the first round of tests

  12. Standard Test Methods for Constituent Content of Composite Materials

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2009-01-01

    1.1 These test methods determine the constituent content of composite materials by one of two approaches. Method I physically removes the matrix by digestion or ignition by one of seven procedures, leaving the reinforcement essentially unaffected and thus allowing calculation of reinforcement or matrix content (by weight or volume) as well as percent void volume. Method II, applicable only to laminate materials of known fiber areal weight, calculates reinforcement or matrix content (by weight or volume), and the cured ply thickness, based on the measured thickness of the laminate. Method II is not applicable to the measurement of void volume. 1.1.1 These test methods are primarily intended for two-part composite material systems. However, special provisions can be made to extend these test methods to filled material systems with more than two constituents, though not all test results can be determined in every case. 1.1.2 The procedures contained within have been designed to be particularly effective for ce...

  13. Compression testing of graphite/epoxy composite materials

    Science.gov (United States)

    Clark, R. K.; Lisagor, W. B.

    1981-01-01

    Three methods for compression testing coupons of filament-reinforced polymer-matrix composite materials are evaluated, to identify the sensitivity of the test techniques to laminate, specimen, and test parameters. A 'wedge-grip' compression fixture, a face-supported compression fixture, and an end-loaded coupon fixture are described. Specimens of 12.5-, 25-, and 50-mm widths, 8-, 16-, and 24-ply thicknesses, and of various fiber orientations were used to test the 'wedge-grip' compression fixture and the face-supported fixture; the end-loaded coupon fixture was tested using 16-ply specimens. Compressive strain-stress, strength, and modulus data obtained with the fixtures and evaluations showing the effects of all the test parameters are presented. One of the conclusions asserts that the 'wedge-grip' compression fixture provides good stress-strain data to failure for unidirectional and quasi-isotropic laminates.

  14. System Studies for the ADTF: Target and Materials Test Station

    International Nuclear Information System (INIS)

    Cappiello, M.; Pitcher, E.; Pasamehmetoglu, K.

    2002-01-01

    To meet the objectives of the Advanced Accelerator Applications (AAA) program, the Accelerator-Driven Test Facility (ADTF) provides a world-class accelerator-driven test facility to: - Provide the capability to assess technology options for the transmutation of spent nuclear fuel and waste through a proof-of-performance. - Provide a user facility that allows testing of advanced nuclear technologies and applications, material science and research, experimental physics, and conventional nuclear engineering science applications. - Provide the capability, through upgrades or additions to the ADTF accelerator, to produce tritium for defense purposes, if required. - Provide the capability, through upgrades or additions, to produce radioisotopes for medical and commercial purposes. These missions are diverse and demand a facility with significant flexibility. In order to meet them, it is envisioned that we construct two target stations: the Target and Materials Test (TMT) station and the Subcritical Multiplier (SCM) test station. The two test stations share common hot-cell facilities for post-irradiation examination. It is expected the TMT will come online first, closely followed by the SCM. The TMT will provide the capability to: - Irradiate small samples of proposed ATW (accelerator-driven transmutation of waste) fuels and materials at prototypic flux, temperature, and coolant conditions (requires intense source of neutrons). - Perform transient testing. - Test liquid (lead-bismuth) and solid spallation targets with water, sodium, or helium coolant. - Test generation-IV fuels for advance nuclear systems (requires high-intensity thermal flux). - Irradiate fission product transmutation targets. - Test advanced fuel and coolant combinations, including helium, water, sodium, and lead-bismuth. - Produce isotopes for commercial and medical applications. - Perform neutron physics experiments. The SCM will provide the capability to: - Irradiate large samples of proposed ATW

  15. Multilayer Pressure Vessel Materials Testing and Analysis Phase 2

    Science.gov (United States)

    Popelar, Carl F.; Cardinal, Joseph W.

    2014-01-01

    To provide NASA with a suite of materials strength, fracture toughness and crack growth rate test results for use in remaining life calculations for the vessels described above, Southwest Research Institute® (SwRI®) was contracted in two phases to obtain relevant material property data from a representative vessel. An initial characterization of the strength, fracture and fatigue crack growth properties was performed in Phase 1. Based on the results and recommendations of Phase 1, a more extensive material property characterization effort was developed in this Phase 2 effort. This Phase 2 characterization included additional strength, fracture and fatigue crack growth of the multilayer vessel and head materials. In addition, some more limited characterization of the welds and heat affected zones (HAZs) were performed. This report

  16. Biomedical applications of nanotechnology.

    Science.gov (United States)

    Ramos, Ana P; Cruz, Marcos A E; Tovani, Camila B; Ciancaglini, Pietro

    2017-04-01

    The ability to investigate substances at the molecular level has boosted the search for materials with outstanding properties for use in medicine. The application of these novel materials has generated the new research field of nanobiotechnology, which plays a central role in disease diagnosis, drug design and delivery, and implants. In this review, we provide an overview of the use of metallic and metal oxide nanoparticles, carbon-nanotubes, liposomes, and nanopatterned flat surfaces for specific biomedical applications. The chemical and physical properties of the surface of these materials allow their use in diagnosis, biosensing and bioimaging devices, drug delivery systems, and bone substitute implants. The toxicology of these particles is also discussed in the light of a new field referred to as nanotoxicology that studies the surface effects emerging from nanostructured materials.

  17. Cyclic Plane Strain Compression Tests on Dense Granular Materials

    Science.gov (United States)

    Koseki, Junichi; Karimi, Job Munene; Tsutsumi, Yukika; Maqbool, Sajjad; Sato, Takeshi

    A series of cyclic plane strain compression tests are performed under drained condition on dense Toyoura sand and compacted Chiba gravel, by using small-scale and large-scale apparatuses, respectively. Comparisons are made with results from monotonic loading tests. Local strain distributions are calculated by conducting image analyses of digital photographs taken at different stages of loading during each test. Based on these results, strain localization properties of dense granular materials are discussed, in particular focusing on possible effects of cyclic loading history.

  18. Type of speech material affects Acceptable Noise Level test outcome

    Directory of Open Access Journals (Sweden)

    Xaver eKoch

    2016-02-01

    Full Text Available The Acceptable Noise Level (ANL test, in which individuals indicate what level of noise they are willing to put up with while following speech, has been used to guide hearing aid fitting decisions and has been found to relate to prospective hearing aid use. Unlike objective measures of speech perception ability, ANL outcome is not related to individual hearing loss or age, but rather reflects an individual's inherent acceptance of competing noise while listening to speech. As such, the measure may predict aspects of hearing aid success. Crucially, however, recent studies have questioned its repeatability (test-retest reliability. The first question for this study was whether the inconsistent results regarding the repeatability of the ANL test may be due to differences in speech material types used in previous studies. Second, it is unclear whether meaningfulness and semantic coherence of the speech modify ANL outcome. To investigate these questions, we compared ANLs obtained with three types of materials: the International Speech Test Signal (ISTS, which is non-meaningful and semantically non-coherent by definition, passages consisting of concatenated meaningful standard audiology sentences, and longer fragments taken from conversational speech. We included conversational speech as this type of speech material is most representative of everyday listening. Additionally, we investigated whether ANL outcomes, obtained with these three different speech materials, were associated with self-reported limitations due to hearing problems and listening effort in everyday life, as assessed by a questionnaire. ANL data were collected for 57 relatively good-hearing adult participants with an age range representative for hearing aid users. Results showed that meaningfulness, but not semantic coherence of the speech material affected ANL. Less noise was accepted for the non-meaningful ISTS signal than for the meaningful speech materials. ANL repeatability was

  19. Special Nuclear Material Portal Monitoring at the Nevada Test Site

    International Nuclear Information System (INIS)

    Mike Murphy

    2008-01-01

    In the past, acceptance and performance testing of the various Special Nuclear Material (SNM) monitoring devices at the Nevada Test Site has been performed by the Radiological Health Instrumentation Department. Calibration and performance tests on the PM-700 personnel portal monitor were performed but there was no test program for the VM-250 vehicle portal monitor because it had never been put into service. The handheld SNM monitors, the TSA model 470B, were being calibrated annually, but there was no program in place to test them quarterly. In April of 2007, the Material Control and Accountability (MC and A) Manager at the time decided that the program needed to be strengthened and MC and A took over performance testing of all SNM portal monitoring equipment. This paper will discuss the following activities associated with creating a performance testing program: changing the culture, learning the systems, writing procedures, troubleshooting/repairing, validating the process, control of equipment, acquisition of new systems, and running the program

  20. Two micro fatigue test methods for irradiated materials

    International Nuclear Information System (INIS)

    Nunomura, Shigetomo; Noguchi, Shinji; Okamura, Yuichi; Kumai, Shinji

    1993-01-01

    This paper demonstrates two miniature fatigue test methods in response to the requirements of the fusion reactor wall materials development program. It is known that the fatigue strength evaluated by the axial loading test is independent of the specimen size, while that evaluated by the bend test or torsion test is dependent upon the size of specimen. The new type of gripping system for the axial, tension-tension, fatigue testing of TEM disk-size specimens that has been developed is described in this paper. An alignment tool assists in gripping the miniature specimen. The miniature tension-tension fatigue test method seems to provide reliable S-N curves for SUS304 and SUS316L stainless steels. An indentation method has also been developed to determine fatigue properties. A hard steel ball or ceramic ball was used for cyclically loading the specimen, and an S-N curve was subsequently obtained. The merit of this method is primarily simple handling. S-N curves obtained from four materials by this indentation method compared well with those obtained from the rotary bend fatigue test employing a standard-size specimen

  1. Effects of Introduced Materials in the Drift Scale Test

    International Nuclear Information System (INIS)

    DeLoach, L; Jones, RL

    2002-01-01

    Water samples previously acquired from superheated (>140 C) zones within hydrological test boreholes of the Drift Scale Test (DST) show relatively high fluoride concentrations (5-66 ppm) and low pH (3.1-3.5) values. In these high temperature regions of the rock, water is present superheated vapor only--liquid water for sampling purposes is obtained during the sampling process by cooling. Based on data collected to date, it is evident that the source of the fluoride and low pH is from introduced man-made materials (Teflon(trademark) and/or Viton(trademark) fluoroelastomer) used in the test. The test materials may contribute fluoride either by degassing hydrogen fluoride (HF) directly to produce trace concentrations of HF gas (∼0.1 ppm) in the high temperature steam, or by leaching fluoride in the sampling tubes after condensation of the superheated steam. HF gas is known to be released from Viton(trademark) at high temperatures (Dupont Dow Elastomers L.L.C., Elkton, MD, personal communication) and the sample water compositions indicate near stoichiometric balance of hydrogen ion and fluoride ion, indicating dissolution of HF gas into the aqueous phase. These conclusions are based on a series of water samples collected to determine if the source of the fluoride is from the degradation of materials originally installed to facilitate measurements. Analyses of these water samples show that the source of the fluoride is the introduced materials, that is the Viton(trademark) packers used to isolate test zones and/or Teflon(trademark) tubing used to draw water and steam from the test zones. In particular, water samples collected from borehole (BH) 72 high temperatures (∼ 170 C) prior to introduction of any Viton(trademark) or Teflon(trademark) show pH Values (4.8 to 5.5) and fluoride concentrations well below 1 ppm over a period of six months. These characteristics are typical of condensing DST steam that contains only some dissolved carbon dioxide generated by water

  2. Chairside CAD/CAM materials. Part 2: Flexural strength testing.

    Science.gov (United States)

    Wendler, Michael; Belli, Renan; Petschelt, Anselm; Mevec, Daniel; Harrer, Walter; Lube, Tanja; Danzer, Robert; Lohbauer, Ulrich

    2017-01-01

    Strength is one of the preferred parameters used in dentistry for determining clinical indication of dental restoratives. However, small dimensions of CAD/CAM blocks limit reliable measurements with standardized uniaxial bending tests. The objective of this study was to introduce the ball-on-three-ball (B3B) biaxial strength test for dental for small CAD/CAM block in the context of the size effect on strength predicted by the Weibull theory. Eight representative chairside CAD/CAM materials ranging from polycrystalline zirconia (e.max ZirCAD, Ivoclar-Vivadent), reinforced glasses (Vitablocs Mark II, VITA; Empress CAD, Ivoclar-Vivadent) and glass-ceramics (e.max CAD, Ivoclar-Vivadent; Suprinity, VITA; Celtra Duo, Dentsply) to hybrid materials (Enamic, VITA; Lava Ultimate, 3M ESPE) have been selected. Specimens were prepared with highly polished surfaces in rectangular plate (12×12×1.2mm 3 ) or round disc (Ø=12mm, thickness=1.2mm) geometries. Specimens were tested using the B3B assembly and the biaxial strength was determined using calculations derived from finite element analyses of the respective stress fields. Size effects on strength were determined based on results from 4-point-bending specimens. A good agreement was found between the biaxial strength results for the different geometries (plates vs. discs) using the B3B test. Strength values ranged from 110.9MPa (Vitablocs Mark II) to 1303.21MPa (e.max ZirCAD). The strength dependency on specimen size was demonstrated through the calculated effective volume/surface. The B3B test has shown to be a reliable and simple method for determining the biaxial strength restorative materials supplied as small CAD/CAM blocks. A flexible solution was made available for the B3B test in the rectangular plate geometry. Copyright © 2016 The Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  3. Mechanical Testing of Carbon Based Woven Thermal Protection Materials

    Science.gov (United States)

    Pham, John; Agrawal, Parul; Arnold, James O.; Peterson, Keith; Venkatapathy, Ethiraj

    2013-01-01

    Three Dimensional Woven thermal protection system (TPS) materials are one of the enabling technologies for mechanically deployable hypersonic decelerator systems. These materials have been shown capable of serving a dual purpose as TPS and as structural load bearing members during entry and descent operations. In order to ensure successful structural performance, it is important to characterize the mechanical properties of these materials prior to and post exposure to entry-like heating conditions. This research focuses on the changes in load bearing capacity of woven TPS materials after being subjected to arcjet simulations of entry heating. Preliminary testing of arcjet tested materials [1] has shown a mechanical degradation. However, their residual strength is significantly more than the requirements for a mission to Venus [2]. A systematic investigation at the macro and microstructural scales is reported here to explore the potential causes of this degradation. The effects of heating on the sizing (an epoxy resin coating used to reduce friction and wear during fiber handling) are discussed as one of the possible causes for the decrease in mechanical properties. This investigation also provides valuable guidelines for margin policies for future mechanically deployable entry systems.

  4. Brittle fracture tests at low temperature for transport cask materials

    International Nuclear Information System (INIS)

    Kosaki, Akio; Ito, Chihiro; Arai, Taku; Saegusa, Toshiari

    1993-01-01

    The IAEA Regulations for the Safe Transport of Radioactive Material were revised in 1985, and brittle fracture assessment at low temperature for transport packages are now required. This report discusses the applicability of the actual method for brittle fracture assessment of type-B transport cask materials used in JAPAN. The necessity of brittle fracture assessment at low temperature was estimated for each material of type-B transport casks used in Japan and the applicability was investigated. Dynamic fracture toughness values, K Id (J Id ), and RT NDT values of Low-Mn Carbon Steels, that are SA 350 Gr.LF1 Modify and SA 516 Gr.70 material which used in type-B transport cask body, were also obtained to check whether or not an easier and conventional test method, that prescribed in ASME CODE SECTION III, can be substituted for the dynamic fracture test method. And for bolt materials, which include 1.8Ni-0.8Cr-0.3Mo Carbon Steel and type 630 H Stainless Steel, toughness data were obtained for reference. (J.P.N.)

  5. GPR Laboratory Tests For Railways Materials Dielectric Properties Assessment

    Directory of Open Access Journals (Sweden)

    Francesca De Chiara

    2014-10-01

    Full Text Available In railways Ground Penetrating Radar (GPR studies, the evaluation of materials dielectric properties is critical as they are sensitive to water content, to petrographic type of aggregates and to fouling condition of the ballast. Under the load traffic, maintenance actions and climatic effects, ballast condition change due to aggregate breakdown and to subgrade soils pumping, mainly on existing lines with no sub ballast layer. The main purpose of this study was to validate, under controlled conditions, the dielectric values of materials used in Portuguese railways, in order to improve the GPR interpretation using commercial software and consequently the management maintenance planning. Different materials were tested and a broad range of in situ conditions were simulated in laboratory, in physical models. GPR tests were performed with five antennas with frequencies between 400 and 1800 MHz. The variation of the dielectric properties was measured, and the range of values that can be obtained for different material condition was defined. Additionally, in situ GPR measurements and test pits were performed for validation of the dielectric constant of clean ballast. The results obtained are analyzed and the main conclusions are presented herein.

  6. Development of a multi-VOC reference material for quality assurance in materials emission testing.

    Science.gov (United States)

    Nohr, Michael; Horn, Wolfgang; Jann, Oliver; Richter, Matthias; Lorenz, Wilhelm

    2015-04-01

    Emission test chamber measurement is necessary to proof building materials as sources of volatile organic compounds (VOCs). The results of such measurements are used to evaluate materials and label them according to their potential to emit harmful substances, polluting indoor air. If only labelled materials were installed indoors, this would improve indoor air quality and prevent negative impacts on human health. Because of the complex testing procedure, reference materials for the quality assurance are mandatory. Currently, there is a lack of such materials because most building products show a broad variation of emissions even within one batch. A previous study indicates lacquers, mixed with volatile organic pollutants, as reproducible emission source for a wide range of substances. In the present study, the curing of the lacquer-VOC mixture inside micro-chambers was optimised. Therefore, the humidity and the chamber flow were varied. Typical indoor air pollutants with a wide range of volatilities, for example, styrene, n-hexadecane, dimethyl and dibutyl phthalate were selected. It turned out that, under optimised curing parameters inside the micro-chamber, their emission can be reproduced with variations of less than 10 %. With this, a next important step towards a reference material for emission testing was achieved.

  7. The Iosipescu shear test method as used for testing polymers and composite materials

    Science.gov (United States)

    Adams, Donald F.

    1990-01-01

    This paper describes a shear test method for polymers and composite materials, based on the Iosipescu (1967) shear test which was originally developed for use with homogeneous isotropic metals. Special attention is given to the loading fixture for the test, the standard specimen design and shear stress measurements. The range of the test applications is indicated. The method is in the final stages of being accepted as an ASTM standard.

  8. Material testing facilities and programs for plasma-facing component testing

    Science.gov (United States)

    Linsmeier, Ch.; Unterberg, B.; Coenen, J. W.; Doerner, R. P.; Greuner, H.; Kreter, A.; Linke, J.; Maier, H.

    2017-09-01

    Component development for operation in a large-scale fusion device requires thorough testing and qualification for the intended operational conditions. In particular environments are necessary which are comparable to the real operation conditions, allowing at the same time for in situ/in vacuo diagnostics and flexible operation, even beyond design limits during the testing. Various electron and neutral particle devices provide the capabilities for high heat load tests, suited for material samples and components from lab-scale dimensions up to full-size parts, containing toxic materials like beryllium, and being activated by neutron irradiation. To simulate the conditions specific to a fusion plasma both at the first wall and in the divertor of fusion devices, linear plasma devices allow for a test of erosion and hydrogen isotope recycling behavior under well-defined and controlled conditions. Finally, the complex conditions in a fusion device (including the effects caused by magnetic fields) are exploited for component and material tests by exposing test mock-ups or material samples to a fusion plasma by manipulator systems. They allow for easy exchange of test pieces in a tokamak or stellarator device, without opening the vessel. Such a chain of test devices and qualification procedures is required for the development of plasma-facing components which then can be successfully operated in future fusion power devices. The various available as well as newly planned devices and test stands, together with their specific capabilities, are presented in this manuscript. Results from experimental programs on test facilities illustrate their significance for the qualification of plasma-facing materials and components. An extended set of references provides access to the current status of material and component testing capabilities in the international fusion programs.

  9. Design of a materials testing experiment for the INTOR

    International Nuclear Information System (INIS)

    Vogel, M.A.; Opperman, E.K.

    1981-01-01

    The United States, Japan, USSR and the European community are jointly participating in the design of an International Tokamak Reactor called INTOR. In support of the US contribution to the INTOR design, the features of an experiment for bulk neutron irradiation damage studies were developed. It is anticipated that materials testing will be an important part of the programmatic mission of INTOR and consequently the requirements for materials testing in INTOR must be identified early in the reactor design to insure compatibility. The design features of the experiment, called a Channel Test, are given in this paper. The major components of the channel test are the water cooled heat sink (channel module) and the specimen capsule. The temperature within each of the 153 specimen capsules is predetermined by engineering the thermal barrier between the specimen capsule and heat sink. Individual capsules can be independently accessed and are designed to operate at a predetermined temperature within the range of 50 to 700 0 C. The total irradiation volume within a single channel test is 45 liters. Features of the channel test that result in experimental versatility and simplified remote access and handling are discussed

  10. Long-term pavement performance project laboratory materials testing and handling guide

    Science.gov (United States)

    2007-09-01

    The Long Term Pavement Performance (LTPP) Laboratory Material Testing Guide was originally prepared for laboratory material handling and testing of material specimens and samples of asphalt materials, portland cement concrete, aggregates, and soils u...

  11. TESTING OF GAS REACTOR MATERIALS AND FUEL IN THE ADVANCED TEST REACTOR

    International Nuclear Information System (INIS)

    Grover, S.B.

    2004-01-01

    The Advanced Test Reactor (ATR) has long been involved in testing gas reactor materials, and has developed facilities well suited for providing the right conditions and environment for gas reactor tests. This paper discusses the different types of irradiation hardware that have been utilized in past ATR irradiation tests of gas reactor materials. The new Gas Test Loop facility currently being developed for the ATR is discussed and the different approaches being considered in the design of the facility. The different options for an irradiation experiment such as active versus passive temperature control, neutron spectrum tailoring, and different types of lead experiment sweep gas monitors are also discussed. The paper is then concluded with examples of different past and present gas reactor material and fuel irradiations

  12. Fusion Materials Irradiation Test Facility: a facility for fusion-materials qualification

    International Nuclear Information System (INIS)

    Trego, A.L.; Hagan, J.W.; Opperman, E.K.; Burke, R.J.

    1983-01-01

    The Fusion Materials Irradiation Test Facility will provide a unique testing environment for irradiation of structural and special purpose materials in support of fusion power systems. The neutron source will be produced by a deuteron-lithium stripping reaction to generate high energy neutrons to ensure damage similar to that of a deuterium-tritium neutron spectrum. The facility design is now ready for the start of construction and much of the supporting lithium system research has been completed. Major testing of key low energy end components of the accelerator is about to commence. The facility, its testing role, and the status and major aspects of its design and supporting system development are described

  13. Full scale tests of moisture buffer capacity of wall materials

    DEFF Research Database (Denmark)

    Mortensen, Lone Hedegaard; Rode, Carsten; Peuhkuri, Ruut Hannele

    2005-01-01

    Moisture buffer capacity of hygroscopic materials can be used to moderate peaks in the relative humidity (RH) of indoor air as well as moisture content variations in building materials and furnishing. This can help to ensure healthier indoor environments by preventing many processes...... that are harmful such as growth of house dust mites, surface condensation and mould growth. Therefore a series of experiments has been carried out in a full scale test facility to determine the moisture buffer effect of interior walls of cellular concrete and plaster board constructions. For the cellular concrete...... of the changes of moisture content in specimens of the wall composites exposed to the same environment. It was found that the finishes had a big impact on the buffer performance of the underlying materials. Even though the untreated cellular concrete had a very high buffer capacity, the effect was strongly...

  14. Abrasion test of flexible protective materials on hydraulic structures

    Directory of Open Access Journals (Sweden)

    Xin Wang

    2014-01-01

    Full Text Available In this study, several kinds of flexible protective materials sprayed with polyurea elastomers (hereinafter referred to as polyurea elastomer protective material were adopted to meet the abrasion resistance requirement of hydraulic structures, and their abrasion resistances against the water flow with suspended load or bed load were studied systematically through tests. Natural basalt stones were adopted as the abrasive for simulation of the abrasion effect of the water flow with bed load, and test results indicate that the basalt stone is suitable for use in the abrasion resistance test of the flexible protective material. The wear process of the polyurea elastomer protective material is stable, and the wear loss is linear with the time of abrasion. If the wear thickness is regarded as the abrasion resistance evaluation factor, the abrasion resistance of the 351 pure polyurea is about twice those of pure polyurea with a high level of hardness and aliphatic polyurea, and over five times that of high-performance abrasion-resistant concrete under the abrasion of the water flow with suspended load. It is also about 50 times that of high-performance abrasion-resistant concrete under the abrasion of the water flow with bed load. Overall, the abrasion resistance of pure polyurea presented a decreasing trend with increasing hardness. Pure polyurea with a Shore hardness of D30 has the best abrasion resistance, which is 60 to 70 times that of high-performance abrasion-resistant concrete under the abrasion of the water flow with bed load, and has been recommended, among the five kinds of pure polyurea materials with different hardness, in anti-abrasion protection of hydraulic structures.

  15. Material control system design: Test Bed Nitrate Storage Area (TBNSA)

    International Nuclear Information System (INIS)

    Clark, G.A.; Da Roza, R.A.; Dunn, D.R.; Sacks, I.J.; Harrison, W.; Huebel, J.G.; Ross, W.N.; Salisbury, J.D.; Sanborn, R.H.; Weissenberger, S.

    1978-05-01

    This report provides an example of a hypothetical Special Nuclear Material (SNM) Safeguard Material Control and Accounting (MC and A) System which will be used as a subject for the demonstration of the Lawrence Livermore Laboratory MC and A System Evaluation Methodology in January 1978. This methodology is to become a tool in the NRC evaluation of license applicant submittals for Nuclear Fuel Cycle facilities. The starting point for this test bed design was the Allied-General Nuclear Services--Barnwell Nuclear Fuel Plant Reprocessing plant as described in the Final Safety Analysis Report (FSAR), of August 1975. The test bed design effort was limited to providing an SNM safeguard system for the plutonium nitrate storage area of this facility

  16. Material control and accounting self-test program design

    International Nuclear Information System (INIS)

    Eggers, R.F.; Wilson, R.L.; Byers, K.R.

    1981-01-01

    This paper describes a controversial but potentially beneficial MCandA strategy that has not been widely attempted in the past, called Self-Test. In this strategy a processor of Strategic Special Nuclear Material (SSNM) devises a program of internally administered tests to determine if the MCandA system performs in a reliable, expedient manner in the face of a simulated loss or compromise. Self-Test procedures would include, for example, the actual removal of SSNM from process equipment in order to determine whether the MCandA system will detect the simulated theft. Self-Test programs have several potential problems. However, an approach with the potential for solving many of these problems has been devised and is discussed

  17. Controlled Chemistry Helium High Temperature Materials Test Loop

    Energy Technology Data Exchange (ETDEWEB)

    Richard N. WRight

    2005-08-01

    A system to test aging and environmental effects in flowing helium with impurity content representative of the Next Generation Nuclear Plant (NGNP) has been designed and assembled. The system will be used to expose microstructure analysis coupons and mechanical test specimens for up to 5,000 hours in helium containing potentially oxidizing or carburizing impurities controlled to parts per million levels. Impurity levels in the flowing helium are controlled through a feedback mechanism based on gas chromatography measurements of the gas chemistry at the inlet and exit from a high temperature retort containing the test materials. Initial testing will focus on determining the nature and extent of combined aging and environmental effects on microstructure and elevated temperature mechanical properties of alloys proposed for structural applications in the NGNP, including Inconel 617 and Haynes 230.

  18. Biomedical microsystems

    CERN Document Server

    Meng, Ellis

    2010-01-01

    IntroductionEvolution of MEMSApplications of MEMSBioMEMS ApplicationsMEMS ResourcesText Goals and OrganizationMiniaturization and ScalingBioMEMS MaterialsTraditional MEMS and Microelectronic MaterialsPolymeric Materials for MEMSBiomaterialsMicrofabrication Methods and Processes for BioMEMSIntroductionMicrolithographyDopingMicromachiningWafer Bonding, Assembly, and PackagingSurface TreatmentConversion Factors for Energy and Intensity UnitsLaboratory ExercisesMicrofluidicsIntroduction and Fluid PropertiesConcepts in MicrofluidicsFluid-Transport Phenomena and PumpingFlow ControlLaboratory Exercis

  19. Experimental Verification of an Instrument to Test Flooring Materials

    Science.gov (United States)

    Philip, Rony; Löfgren, Hans, Dr

    2018-02-01

    The focus of this work is to validate the fluid model with different flooring materials and the measurements of an instrument to test flooring materials and its force attenuating capabilities using mathematical models to describe the signature and coefficients of the floor. The main contribution of the present work focus on the development of a mathematical fluid model for floors. The aim of the thesis was to analyze, compare different floor materials and to study the linear dynamics of falling impacts on floors. The impact of the hammer during a fall is captured by an accelerometer and response is collected using a picoscope. The collected data was analyzed using matlab least square method which is coded as per the fluid model. The finding from this thesis showed that the fluid model works with more elastic model but it doesn’t work for rigid materials like wood. The importance of parameters like velocity, mass, energy loss and other coefficients of floor which influences the model during the impact of falling on floors were identified and a standardized testing method was set.

  20. Medullary thyroid cancer: RET testing of an archival material

    DEFF Research Database (Denmark)

    Godballe, Christian; Jørgensen, Gita; Gerdes, Anne-Marie Axø

    2010-01-01

    Medullary thyroid carcinoma (MTC) might be sporadic (75%) or hereditary (25%). Until the mid nineties the diagnosis of hereditary MTC was based on family history, clinical evaluation, histological detection of C-cell hyperplasia and tumor multifocality. Patients and families with hereditary MTC m...... by testing of non-tumor tissue from patients with known hereditary MTC. This study shows that genetic testing of archival MTC material is technically possible and might be a way of identifying patients with previously not recognized hereditary MTC....

  1. EMERIS: an advanced information system for a materials testing reactor

    International Nuclear Information System (INIS)

    Adorjan, F.; Buerger, L.; Lux, I.; Mesko, L.; Szabo, K.; Vegh, J.; Ivanov, V.V.; Mozhaev, A.A.; Yakovlev, V.V.

    1990-06-01

    The basic features of the Materials Testing Reactor of IAE, Moscow (MR) Information System (EMERIS) are outlined. The purpose of the system is to support reactor and experimental test loop operators by a flexible, fully computerized and user-friendly tool for the aquisition, analysis, archivation and presentation of data obtained during operation of the experimental facility. High availability of EMERIS services is ensured by redundant hardware and software components, and by automatic configuration procedure. A novel software feature of the system is the automatic Disturbance Analysis package, which is aimed to discover primary causes of irregularities occurred in the technology. (author) 2 refs.; 2 figs

  2. Testing of irradiated and annealed 15H2MFA materials

    International Nuclear Information System (INIS)

    Gillemot, F.; Uri, G.

    1994-01-01

    A set of surveillance samples made from 15H2MFA material has been studied in the laboratory of AEKI. Miniature notched tensile specimens were cut from some remnants of irradiated and broke surveillance charpy remnants. The Absorbed Specific Fracture Energy (ASFE) was measured on the specimens. A cutting machine and testing technique were elaborated for the measurements. The second part of the Charpy remnants was annealed at 460 deg. C and 490 deg. C for 6-8 hours. The specimens were tested similarity and the results were compared. (author). 5 refs, 9 figs

  3. Fracture Toughness Round Robin Test International in pressure tube materials

    International Nuclear Information System (INIS)

    Villagarcia, M.P.; Liendo, M.F.

    1993-01-01

    Part of the pressure tubes surveillance program of CANDU type reactors is to determine the fracture toughness using a special fracture specimen and test procedure. Atomic Energy of Canada Limited decided to hold a Round Robin Test International and 9 laboratories participated worldwide in which several pressure tube materials were selected: Zircaloy-2, Zr-2.5%Nb cold worked and Zr-2.5%Nb heat treated. The small specimens used held back the thickness and curvature of the tube. J-R curves at room temperature were obtained and the crack extension values were determined by electrical potential drop techniques. These values were compared with results generated from other laboratories and a bid scatter was founded. It could be due to slight variations in the test method or inhomogeneity of the materials and a statistical study must be done to see if there is any pattern. The next step for the Round Robin Test would be to make some modifications in the test method in order to reduce the scatter. (Author)

  4. Non-destructive magnetic adaptive testing of ferromagnetic materials

    Czech Academy of Sciences Publication Activity Database

    Tomáš, Ivan

    2003-01-01

    Roč. 268, - (2003), s. 178-185 ISSN 0304-8853 R&D Projects: GA ČR GA101/02/0236; GA AV ČR KSK1010104 Institutional research plan: CEZ:AV0Z1010914 Keywords : non-destructive testing * ferromagnetic material * construction steel * differencial permeability * Preisach evolution Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 0.910, year: 2003

  5. A 360-deg Digital Image Correlation system for materials testing

    Science.gov (United States)

    Genovese, K.; Cortese, L.; Rossi, M.; Amodio, D.

    2016-07-01

    The increasing research interest toward natural and advanced engineered materials demands new experimental protocols capable of retrieving highly dense sets of experimental data on the full-surface of samples under multiple loading conditions. Such information, in fact, would allow to capture the possible heterogeneity and anisotropy of the material by using up-to-date inverse characterization methods. Although the development of object-specific test protocols could represent the optimal choice to address this need, it is unquestionable that universal testing machines (UTM) remain the most widespread and versatile option to test materials and components in both academic and industrial contexts. A major limitation of performing standard material tests with UTM, however, consists in the scarce information obtainable with the commonly associated sensors since they provide only global (LVDTs, extensometers, 2D-video analyzers) or local (strain gages) measures of displacement and strain. This paper presents a 3D Digital Image Correlation (DIC) system developed to perform highly accurate full-surface 360-deg measurements on either standard or custom-shaped samples under complex loading within universal testing machines. To this aim, a low cost and easy to setup video rig was specifically designed to overcome the practical limitations entailed with the integration of a multi-camera system within an already existing loading frame. In particular, the proposed system features a single SLR digital camera moved through multiple positions around the specimen by means of a large rotation stage. A proper calibration and data-processing procedure allows to automatically merge the experimental data obtained from the multiple views with an accuracy of 10-2 m m . The results of a full benchmarking of the metrological performances of the system are here reported and discussed together with illustrative examples of full-360-deg shape and deformation measurements on a Grade X65 steel

  6. Micro-scale testing and micromechanical modelling for high cycle fatigue of CoCr stent material.

    Science.gov (United States)

    Sweeney, C A; O'Brien, B; Dunne, F P E; McHugh, P E; Leen, S B

    2015-06-01

    This paper presents a framework of experimental testing and crystal plasticity micromechanics for high cycle fatigue (HCF) of micro-scale L605 CoCr stent material. Micro-scale specimens, representative of stent struts, are manufactured via laser micro-machining and electro-polishing from biomedical grade CoCr alloy foil. Crystal plasticity models of the micro-specimens are developed using a length scale-dependent, strain-gradient constitutive model and a phenomenological (power-law) constitutive model, calibrated from monotonic and cyclic plasticity test data. Experimental microstructural characterisation of the grain morphology and precipitate distributions is used as input for the polycrystalline finite element (FE) morphologies. Two microstructure-sensitive fatigue indicator parameters are applied, using local and non-local (grain-averaged) implementations, for the phenomenological and length scale-dependent models, respectively, to predict fatigue crack initiation (FCI) in the HCF experiments. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. Thermal shock tests of carbon materials with high power beam

    International Nuclear Information System (INIS)

    Akiba, M.; Araki, M.; Ando, T.; Jinbou, R.; Saidoh, M.; Suzuki, S.; Nakamura, K.; Tanaka, S.

    1992-01-01

    In tokamak machines, not only present machine but also future tokamak devices, off-normal events, so called plasma disruption, is considered as unavoidable phenomena. During the plasma disruption, plasma energy will deposit onto the surface of plasma facing components (PFC). Erosion induced by the disruption will be considered as primary limitation factor of life time of the PFCs. To evaluate erosion rate during the disruption, high power beam facilities have strongly been required. JAERI constructed an electron beam test facility to simulate the disruption heat load. The facility can produce an intense electron beam at a heat flux of up to 2000 MW/m 2 from 1 ms. Many carbon based materials, which have regarded at most promising armor materials, have been tested at the facility at a heat flux range from 300 MW/m 2 to 2000 MW/m 2 . The erosion depth of carbon-fiber-carbon composites (C/C composites) is ∼ 3 times larger than that of numerical prediction. Carbon based B 4 C-coated and B 4 C converted materials which have been developed at JAERI have also tested in the facility. The B 4 C converted C/C composites show high thermal shock resistance. (author)

  8. Composite Material Testing Data Reduction to Adjust for the Systematic 6-DOF Testing Machine Aberrations

    Science.gov (United States)

    Athanasios lliopoulos; John G. Michopoulos; John G. C. Hermanson

    2012-01-01

    This paper describes a data reduction methodology for eliminating the systematic aberrations introduced by the unwanted behavior of a multiaxial testing machine, into the massive amounts of experimental data collected from testing of composite material coupons. The machine in reference is a custom made 6-DoF system called NRL66.3 and developed at the NAval...

  9. Compression-after-impact testing of thin composite materials

    Science.gov (United States)

    Nettles, Alan T.; Hodge, Andrew J.

    1991-01-01

    A new method has been devised to test composite specimens as thin as 8 plies and up to 7.6 cm in width for compression strength. This method utilizes a fixture incorporating the best features of the Celanese and IITRI fixtures combined with an antibuckling jig developed at the University of Dayton Research Institute. This new method uses up to 83 percent less material than the most commonly used compression-after-impact technique (which calls for a 48 ply test specimen) and can also be performed on smaller loading frames since a much smaller force is needed to fail the specimen. The thickness of the test specimen can be fabricated to exactly match production part thickness, thus yielding more meaningful results. CAI tests were performed on IM6/3501 carbon/epoxy utilizing this new method. To verify the design, a series of tests were performed in which undamaged specimens were tested using the new fixture and ASTM D 3410-87 (Celanese compression test) and the results compared. The new fixture works well and will be a valuable asset to MSFC's damage tolerance program.

  10. Examination of an optical transmittance test for photovoltaic encapsulation materials

    Energy Technology Data Exchange (ETDEWEB)

    Miller, David C.; Bengoechea, Jaione; Bokria, Jayesh G.; Köhl, Michael; Powell, Nick E.; Smith, Michael E.; White, Michael D.; Wilson, Helen Rose; Wohlgemuth, John H.; Dhere, Neelkanth G.; Wohlgemuth, John H.; Lynn, Kevin W.

    2013-09-24

    The optical transmittance of encapsulation materials is a key characteristic for their use in photovoltaic (PV) modules. Changes in transmittance with time in the field affect module performance, which may impact product warranties. Transmittance is important in product development, module manufacturing, and field power production (both immediate and long-term). Therefore, an international standard (IEC 62788-1-4) has recently been proposed by the Encapsulation Task-Group within the Working Group 2 (WG2) of the International Electrotechnical Commission (IEC) Technical Committee 82 (TC82) for the quantification of the optical performance of PV encapsulation materials. Existing standards, such as ASTM E903, are general and more appropriately applied to concentrated solar power than to PV. Starting from the optical transmittance measurement, the solar-weighted transmittance of photon irradiance, yellowness index (which may be used in aging studies to assess durability), and ultraviolet (UV) cut-off wavelength may all be determined using the proposed standard. The details of the proposed test are described. The results of a round-robin experiment (for five materials) conducted at seven laboratories to validate the test procedure using representative materials are also presented. For example, the Encapsulation Group actively explored the measurement requirements (wavelength range and resolution), the requirements for the spectrophotometer (including the integrating sphere and instrument accessories, such as a depolarizer), specimen requirements (choice of glass-superstrate and -substrate), and data analysis (relative to the light that may be used in the PV application). The round-robin experiment identified both intra- and inter-laboratory instrument precision and bias for five encapsulation materials (encompassing a range of transmittance and haze-formation characteristics).

  11. Low velocity impact testing and nondestructive evaluation of transparent materials

    International Nuclear Information System (INIS)

    Brennan, R. E.; Green, W. H.

    2011-01-01

    Advanced transparent materials are used in protective systems for enhancing the survivability of ground vehicles, air vehicles, and personnel in applications such as face shields, riot gear, and vehicle windows. Low velocity impact damage can limit visibility and compromise the structural integrity of a transparent system, increasing the likelihood of further damage or penetration from a high velocity impact strike. For this reason, it is critical to determine damage tolerance levels of transparent systems to indicate whether or not a component should be replaced. In this study, transparent laminate systems will be tested by comparing baseline conditions to experimentally controlled damage states. Destructive testing including air gun and sphere impact testing will be used to replicate low velocity impacts in the field. Characterization of the damaged state will include basic visual inspection as well as nondestructive techniques including cross-polarization, x-ray, and ultrasound. The combination of destructive testing and characterization of the resulting damage can help to establish a damage acceptance criterion for materials used in protective systems.

  12. Exploratory Testing of Diatom Silica to Map the Role of Material Attributes on Cell Fate.

    Science.gov (United States)

    Walsh, Pamela J; Clarke, Susan A; Julius, Matthew; Messersmith, Phillip B

    2017-10-26

    Porous silica is an attractive biomaterial in many applications, including drug-delivery systems, bone-graft fillers and medical devices. The issue with porous silica biomaterials is the rate at which they resorb and the significant role played by interfacial chemistry on the host response in vivo. This paper explores the potential of diatom-biosilica as a model tool to assist in the task of mapping and quantifying the role of surface topography and chemical cues on cell fate. Diatoms are unicellular microalgae whose cell walls are composed of, amorphous nanopatterned biosilica that cannot be replicated synthetically. Their unique nanotopography has the potential to improve understanding of interface reactions between materials and cells. This study used Cyclotella meneghiniana as a test subject to assess cytotoxicity and pro-inflammatory reactions to diatom-biosilica. The results suggest that diatom-biosilica is non-cytotoxic to J774.2 macrophage cells, and supports cell proliferation and growth. The addition of amine and thiol linkers have shown a significant effect on cytotoxicity, growth and cytokine response, thus warranting further investigation into the interfacial effects of small chemical modifications to substrate surfaces. The overall findings suggest diatom-biosilica offers a unique platform for in-depth investigation of the role played by nanotopography and chemistry in biomedical applications.

  13. Honeycomb technology materials, design, manufacturing, applications and testing

    CERN Document Server

    Bitzer, Tom

    1997-01-01

    Honeycomb Technology is a guide to honeycomb cores and honeycomb sandwich panels, from the manufacturing methods by which they are produced, to the different types of design, applications for usage and methods of testing the materials. It explains the different types of honeycomb cores available and provides tabulated data of their properties. The author has been involved in the testing and design of honeycomb cores and sandwich panels for nearly 30 years. Honeycomb Technology reflects this by emphasizing a `hands-on' approach and discusses procedures for designing sandwich panels, explaining the necessary equations. Also included is a section on how to design honeycomb energy absorbers and one full chapter discussing honeycomb core and sandwich panel testing. Honeycomb Technology will be of interest to engineers in the aircraft, aerospace and building industries. It will also be of great use to engineering students interested in basic sandwich panel design.

  14. Thermal Testing of Woven TPS Materials in Extreme Entry Environments

    Science.gov (United States)

    Gonzales, G.; Stackpoole, M.

    2014-01-01

    NASAs future robotic missions to Venus and outer planets, namely, Saturn, Uranus, Neptune, result in extremely high entry conditions that exceed the capabilities of current mid density ablators (PICA or Avcoat). Therefore mission planners assume the use of a fully dense carbon phenolic heatshield similar to what was flown on Pioneer Venus and Galileo. Carbon phenolic (CP) is a robust TPS however its high density and thermal conductivity constrain mission planners to steep entries, high heat fluxes, high pressures and short entry durations, in order for CP to be feasible from a mass perspective. In 2012 the Game Changing Development Program in NASAs Space Technology Mission Directorate funded NASA ARC to investigate the feasibility of a Woven Thermal Protection System to meet the needs of NASAs most challenging entry missions. The high entry conditions pose certification challenges in existing ground based test facilities. Recent updates to NASAs IHF and AEDCs H3 high temperature arcjet test facilities enable higher heatflux (2000 Wcm2) and high pressure (5 atm) testing of TPS. Some recent thermal tests of woven TPS will be discussed in this paper. These upgrades have provided a way to test higher entry conditions of potential outer planet and Venus missions and provided a baseline against carbon phenolic material. The results of these tests have given preliminary insight to sample configuration and physical recession profile characteristics.

  15. Testing of ceramic filter materials at the PCFB test facility; Keraamisten suodinmateriaalien testaus PCFB-koelaitoksessa

    Energy Technology Data Exchange (ETDEWEB)

    Kuivalainen, R.; Eriksson, T.; Lehtonen, P.; Tiensuu, J. [Foster Wheeler Energia Oy, Karhula (Finland)

    1997-10-01

    Pressurized Circulating Fluidized Bed (PCFB) combustion technology has been developed in Karhula, Finland since 1986. In 1989, a 10 MW PCFB test facility was constructed. The test facility has been used for performance testing with different coal types through the years 1990-1994 for obtaining data for design and commercialization of the high-efficiency low-emission PCFB combustion technology. The main objective of the project Y53 was to evaluate advanced candle filter materials for the Hot Gas Clean-up Unit (HGCU) to be used in a commercial PCFB Demonstration Project. To achieve this goal, the selected candle materials were exposed to actual high temperature, high pressure coal combustion flue gases for a period of 1000-1500 h during the PCFB test runs. The test runs were carried out in three test segments in Foster Wheeler`s PCFB test facility at the Karhula R and D Center. An extensive inspection and sampling program was carried out after the second test segment. Selected sample candles were analyzed by the filter supplier and the preliminary results were encouraging. The material strength had decreased only within expected range. Slight elongation of the silicon carbide candles was observed, but at this phase the elongation can not be addressed to creep, unlike in the candles tested in 1993-94. The third and last test segment was completed successfully in October 1996. The filter system was inspected and several sample candles were selected for material characterization. The results will be available in February - March 1997. (orig.)

  16. Irradiation tests of materials using HANARO instrumented capsules in 2003

    International Nuclear Information System (INIS)

    Joo, K. M.; Joe, M. S.; Oh, J. M.; Shin, Y. T.; Kang, Y. H.; Lim, I. C.; Hwang, S. R.

    2003-01-01

    The HANARO irradiation capsule system has been actively utilized for the various irradiation tests requested by users of research institutes, universities, and industries. In 2003, two instrumented capsules were designed, fabricated, and successfully irradiated at HANARO and another is under fabrication. For the evaluation of the irradiation properties of the RPV(Reactor Pressure Vessel) materials and for the development of improved evaluation technology, 02M-02K instrumented capsule was designed, fabricated, and successfully irradiated at HANARO. 02M-05U instrumented capsule was designed, fabricated, and successfully irradiated as a part of 2002 project for active utilization of HANARO. Reactor core materials were also irradiated using 02M-05U capsule. Another instrumented capsule is under design and fabrication as a part of 2003 project for active utilization of HANARO and for the development of precise temperature controlling technology

  17. Carbon transfer tests of FBR structural materials in flowing sodium

    International Nuclear Information System (INIS)

    Ohta, Y.; Atsumo, H.; Maruyama, A.; Nakasuji, T.

    1980-01-01

    Since the secondary cooling system of Liquid-Metal Fast Breeder Prototype Reactor Monju consists of a bimetallic loop of austenitic stainless steel and ferritic low alloy steel, carburization occurs in stainless steel and decarburization in low alloy steel mainly due to the difference in carbon activity between the two materials. This phenomenon is thought of suffer reduction in their mechanical properties. In Japan also, since it is necessary to clarify these phenomena quantitatively and feed back the result to the design standard, quantitative evaluation of the amounts of carburization and decarburization as well as studies on the changes in strength of the structural materials caused by these carbon transfer have been underway. Since these studies have not yet reached the final stage, this paper provides mainly an interim report on carbon transfer behavior test and introduction of partial data

  18. Reliability of wind turbine blades: An overview of materials testing

    DEFF Research Database (Denmark)

    Holmes, John W.; Sørensen, Bent F.; Brøndsted, Povl

    2007-01-01

    The structural reliability of wind turbine components can have a profound impact on both the profitability and reputation of a wind turbine manufacturer or supplier of wind turbine components. The issue of reliability is of critical concern when large wind farm co-operatives are considered......, and when wind turbines are located in remote regions where the cost of inspections and repairs can be very high. From a structural viewpoint, wind turbine blades are subjected to very complex loading histories with coupled deformation modes. The long-term reliability of wind turbine blades requires...... an understanding of how damage develops in composite structures, composite materials and adhesives. Designing reliable wind turbine blades also requires the further development of laboratory scale and full scale test methods to evaluate the structural response and durability of new materials under various loading...

  19. Chalcogenide Glass Radiation Sensor; Materials Development, Design and Device Testing

    Energy Technology Data Exchange (ETDEWEB)

    Mitkova, Maria; Butt, Darryl; Kozicki, Michael; Barnaby, Hugo

    2013-04-30

    studied the effect of x-rays and γ-rays, on thin film chalcogenide glasses and applied them in conjunction with film incorporating a silver source in a new type of radiation sensor for which we have an US patent application [3]. In this report, we give data about our studies regarding our designed radiation sensor along with the testing and performance at various radiation doses. These studies have been preceded by materials characterization research related to the compositional and structural characteristics of the active materials used in the radiation sensor design. During the work on the project, we collected a large volume of material since every experiment was repeated many times to verify the results. We conducted a comprehensive material research, analysis and discussion with the aim to understand the nature of the occurring effects, design different structures to harness these effects, generated models to aid in the understanding the effects, built different device structures and collected data to quantify device performance. These various aspects of our investigation have been detailed in previous quarterly reports. In this report, we present our main results and emphasize on the results pertaining to the core project goals materials development, sensor design and testing and with an emphasis on classifying the appropriate material and design for the optimal application. The report has three main parts: (i) Presentation of the main data; (ii) Bulleted summary of the most important results; (iii) List of the patent, journal publications, conference proceedings and conferences participation, occurring as a result of working on the project.

  20. Lap-joint testing of precoated steel materials

    Directory of Open Access Journals (Sweden)

    Chico, B.

    2003-12-01

    Full Text Available In industry, particularly in the building construction, lap-joint technology for precoated steel sheet materials has undergone rapid development. However, standars for lap-joint testing are lacking. This work analyses the behaviour of four precoated steel materials commonly used in the building industry: 55 % Al-Zn and hot dip galvanized, painted and unpainted. Two-year atmospheric exposure tests have been carried out in Madrid and Avilés (Spain, complemented by accelerated weathering tests in climatic cabinets. The latter have consisted of two salt fog/humidity/drying cycles: VDA cycle 621-415 and the "CENIM cycle", which has been designed to adequately simulate the behaviour of materials in this type of joints.

    En la industria en general y, particularmente, en la industria de la construcción, las tecnologías sobre uniones solapadas han experimentado un rápido desarrollo. Sin embargo, no son abundantes los ensayos para este tipo de uniones. Este trabajo analiza el comportamiento de cuatro materiales de acero pre-recubierto comúnmente usados en la industria de la construcción: 55 % Al-Zn y galvanizado por inmersión en caliente, con recubrimiento orgánico y sin él. Se han realizado ensayos de exposición natural durante dos años en las atmósferas de Madrid y Avilés (España, complementados con ensayos de envejecimiento acelerado en cámaras climáticas. En estos últimos se han ensayado dos ciclos de proyección niebla salina/humedad/secado: ciclo VDA 621-415 y un ciclo desarrollado en el CENIM diseñado.

  1. Research process of nondestructive testing pitting corrosion in metal material

    Directory of Open Access Journals (Sweden)

    Bo ZHANG

    2017-12-01

    Full Text Available Pitting corrosion directly affects the usability and service life of metal material, so the effective nondestructive testing and evaluation on pitting corrosion is of great significance for fatigue life prediction because of data supporting. The features of pitting corrosion are elaborated, and the relation between the pitting corrosion parameters and fatigue performance is pointed out. Through introducing the fundamental principles of pitting corrosion including mainly magnetic flux leakage inspection, pulsed eddy current and guided waves, the research status of nondestructive testing technology for pitting corrosion is summarized, and the key steps of nondestructive testing technologies are compared and analyzed from the theoretical model, signal processing to industrial applications. Based on the analysis of the signal processing specificity of different nondestructive testing technologies in detecting pitting corrosion, the visualization combined with image processing and signal analysis are indicated as the critical problems of accurate extraction of pitting defect information and quantitative characterization for pitting corrosion. The study on non-contact nondestructive testing technologies is important for improving the detection precision and its application in industries.

  2. Shield design for the Fusion Materials Irradiation Test facility

    International Nuclear Information System (INIS)

    Carter, L.L.; Mann, F.M.; Morford, R.J.; Wilcox, A.D.; Johnson, D.L.; Huang, S.T.

    1983-03-01

    The shield design for the Fusion Materials Irradiation Test facility is based upon one-, two- and three-dimensional transport calculations with experimental measurements utilized to refine the nuclear data including the neutron cross sections from 20 to 50 MeV and the gamma ray and neutron source terms. The high energy neutrons and deuterons produce activation products from the numerous reactions that are kinematically allowed. The analyses for both beam-on and beam-off (from the activation products) conditions have required extensive nuclear data libraries and the utilization of Monte Carlo, discrete ordinates, point kernel and auxiliary computer codes

  3. Standard Test Method for Shear Fatigue of Sandwich Core Materials

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2000-01-01

    1.1 This test method covers determination of the effect of repeated shear loads on sandwich core materials. 1.2 The values stated in SI units are to be regarded as the standard. The inch-pound units given may be approximate. 1.3 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

  4. Using transmission Kikuchi diffraction for small-scale material testing

    International Nuclear Information System (INIS)

    Cackett, A.

    2015-01-01

    Full text of publication follows. In the fusion and fission industries there is an increasing need for the development of small scale testing methods that can deliver engineering relevant mechanical properties for materials research. In all concepts for dedicated neutron sources for fusion material testing there is a commonality that the sample volumes available will be extremely small. This means that in order to gather significant and usable data the analysis method must be capable of achieving high resolution results. Additionally, a reduced sample size will greatly decrease the safety hazard when dealing with irradiated material. In the case of fission, the availability of a testing technique that only requires a small sample to be extracted from a reactor offers the potential to gauge the condition of components without causing significant down-time. This would be a huge advantage in power plant life-extension projects. One such technique that has recently been developed is Transmission Kikuchi Diffraction (TKD). It is currently the only method capable of being performed in a SEM that can produce crystallographic information at a spatial resolution of 10 nm and only needs sample volumes on the order of a few mm 3 or less. TKD uses a sample in the form of a thin <200 nm foil similar to that used in TEM. It is held at a much shallower tilt (typically no more than 20 degrees) from the detector than previous diffraction techniques such as Electron Backscatter Diffraction, which is why it is able to produce such small, isotropic resolutions. The diffraction patterns resulting from forward-scattered electrons provide information on crystal lattice orientations, the relative angle of which can be translated into a measure of strain. A direct application of this method has been employed in this work, for measuring the strain within the plastically deformed zone underneath a nano-scale indentation. This has been accomplished at CCFE, resulting in a high resolution (10

  5. Multidimensional Tests of Thermal Protection Materials in the Arcjet Test Facility

    Science.gov (United States)

    Agrawal, Parul; Ellerby, Donald T.; Switzer, Mathew R.; Squire, Thomas H.

    2010-01-01

    Many thermal protection system materials used for spacecraft heatshields have anisotropic thermal properties, causing them to display significantly different thermal characteristics in different directions, when subjected to a heating environment during flight or arcjet tests. This paper investigates the effects of sidewall heating coupled with anisotropic thermal properties of thermal protection materials in the arcjet environment. Phenolic Impregnated Carbon Ablator (PICA) and LI-2200 materials (the insulation material of Shuttle tiles) were used for this study. First, conduction-based thermal response simulations were carried out, using the Marc.Mentat finite element solver, to study the effects of sidewall heating on PICA arcjet coupons. The simulation showed that sidewall heating plays a significant role in thermal response of these models. Arcjet tests at the Aerodynamic Heating Facility (AHF) at NASA Ames Research Center were performed later on instrumented coupons to obtain temperature history at sidewall and various radial locations. The details of instrumentation and experimental technique are the prime focus of this paper. The results obtained from testing confirmed that sidewall heating plays a significant role in thermal response of these models. The test results were later used to verify the two-dimensional ablation, thermal response, and sizing program, TITAN. The test data and model predictions were found to be in excellent agreement

  6. Multidimensional Testing of Thermal Protection Materials in the Arcjet Test Facility

    Science.gov (United States)

    Agrawal, Parul; Ellerby, Donald T.; Switzer, Matt R.; Squire, Thomas Howard

    2010-01-01

    Many thermal protection system materials used for spacecraft heatshields have anisotropic thermal properties, causing them to display significantly different thermal characteristics in different directions, when subjected to a heating environment during flight or arcjet tests. The anisotropic effects are enhanced in the presence of sidewall heating. This paper investigates the effects of anisotropic thermal properties of thermal protection materials coupled with sidewall heating in the arcjet environment. Phenolic Impregnated Carbon Ablator (PICA) and LI-2200 materials (the insulation material of Shuttle tiles) were used for this study. First, conduction-based thermal response simulations were carried out, using the Marc.Mentat finite element solver, to study the effects of sidewall heating on PICA arcjet coupons. The simulation showed that sidewall heating plays a significant role in thermal response of these models. Arcjet tests at the Aerodynamic Heating Facility (AHF) at NASA Ames Research Center were performed later on instrumented coupons to obtain temperature history at sidewall and various radial locations. The details of instrumentation and experimental technique are the prime focus of this paper. The results obtained from testing confirmed that sidewall heating plays a significant role in thermal response of these models. The test results were later used to validate the two-dimensional ablation, thermal response, and sizing program, TITAN. The test data and model predictions were found to be in excellent agreement

  7. Standard test methods for notched bar impact testing of metallic materials

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2007-01-01

    1.1 These test methods describe notched-bar impact testing of metallic materials by the Charpy (simple-beam) test and the Izod (cantilever-beam) test. They give the requirements for: test specimens, test procedures, test reports, test machines (see Annex A1) verifying Charpy impact machines (see Annex A2), optional test specimen configurations (see Annex A3), precracking Charpy V-notch specimens (see Annex A4), designation of test specimen orientation (see Annex A5), and determining the percent of shear fracture on the surface of broken impact specimens (see Annex A6). In addition, information is provided on the significance of notched-bar impact testing (see Appendix X2), methods of measuring the center of strike (see Appendix X2). 1.2 These test methods do not address the problems associated with impact testing at temperatures below -196 C (-320 F, 77 K). 1.3 The values stated in SI units are to be regarded as the standard. Inch-pound units are provided for information only. This standard does not purpor...

  8. Proposed rf system for the fusion materials irradiation test facility

    International Nuclear Information System (INIS)

    Fazio, M.V.; Johnson, H.P.; Hoffert, W.J.; Boyd, T.J.

    1979-01-01

    Preliminary rf system design for the accelerator portion of the Fusion Materials Irradiation Test (FMIT) Facility is in progress. The 35-MeV, 100-mA, cw deuteron beam will require 6.3 MW rf power at 80 MHz. Initial testing indicates the EIMAC 8973 tetrode is the most suitable final amplifier tube for each of a series of 15 amplifier chains operating at 0.5-MW output. To satisfy the beam dynamics requirements for particle acceleration and to minimize beam spill, each amplifier output must be controlled to +-1 0 in phase and the field amplitude in the tanks must be held within a 1% tolerance. These tolerances put stringent demands on the rf phase and amplitude control system

  9. Development of Power Electronics Based Test Platform for Characterization and Testing of Magnetocaloric Materials

    Directory of Open Access Journals (Sweden)

    Deepak Elamalayil Soman

    2015-01-01

    Full Text Available Magnetocaloric effects of various materials are getting more and more interesting for the future, as they can significantly contribute towards improving the efficiency of many energy intensive applications such as refrigeration, heating, and air conditioning. Accurate characterization of magnetocaloric effects, exhibited by various materials, is an important process for further studies and development of the suitable magnetocaloric heating and cooling solutions. The conventional test facilities have plenty of limitations, as they focus only on the thermodynamic side and use magnetic machines with moving bed of magnetocaloric material or magnet. In this work an entirely new approach for characterization of the magnetocaloric materials is presented, with the main focus on a flexible and efficient power electronic based excitation and a completely static test platform. It can generate a periodically varying magnetic field using superposition of an ac and a dc magnetic field. The scale down prototype uses a customized single phase H-bridge inverter with essential protections and an electromagnet load as actuator. The preliminary simulation and experimental results show good agreement and support the usage of the power electronic test platform for characterizing magnetocaloric materials.

  10. Characterization of spent fuel approved testing material: ATM-106

    International Nuclear Information System (INIS)

    Guenther, R.J.; Blahnik, D.E.; Campbell, T.K.; Jenquin, U.P.; Mendel, J.E.; Thornhill, C.K.

    1988-10-01

    The characterization data obtained to date are described for Approved Testing Material (ATM)-106 spent fuel from Assembly BT03 of pressurized-water reactor Calvert Cliffs No. 1. This report is one in a series being prepared by the Materials Characterization Center at Pacific Northwest Laboratory on spent fuel ATMs. The ATMs are receiving extensive examinations to provide a source of well- characterized spent fuel for testing in the US Department of Energy Office of Civilian Radioactive Waste Management (OCWRM) program. ATM-106 consists of 20 full-length irradiated fuel rods with rod-average burnups of about 3700 GJ/kgM (43 MWd/kgM) and expected fission gas release of /approximately/10%. Characterization data include (1) as-fabricated fuel design, irradiation history, and subsequent storage and handling; (2) isotopic gamma scans; (3) fission gas analyses; (4) ceramography of the fuel and metallography of the cladding; (5) calculated nuclide inventories and radioactivities in the fuel and cladding; and (6) radiochemical analyses of the fuel and cladding. Additional analyses of the fuel rod are being conducted and will be included in planned revisions of this report. 12 refs., 110 figs., 81 tabs

  11. Characterization of spent fuel approved testing material---ATM-105

    Energy Technology Data Exchange (ETDEWEB)

    Guenther, R.J.; Blahnik, D.E.; Campbell, T.K.; Jenquin, U.P.; Mendel, J.E.; Thomas, L.E.; Thornhill, C.K.

    1991-12-01

    The characterization data obtained to data are described for Approved Testing Material 105 (ATM-105), which is spent fuel from Bundles CZ346 and CZ348 of the Cooper Nuclear Power Plant, a boiling-water reactor. This report is one in a series being prepared by the Materials Characterization Center at Pacific Northwest Laboratory (PNL) on spent fuel ATMs. The ATMs are receiving extensive examinations to provide a source of well-characterized spent fuel for testing in the US Department of Energy Office of Civilian Radioactive Waste Management (OCRWM) Program. ATM-105 consists of 88 full-length irradiated fuel rods with rod-average burnups of about 2400 GJ/kgM (28 MWd/kgM) and expected fission gas release of about 1%. Characterization data include (1) descriptions of as-fabricated fuel design, irradiation history, and subsequent storage and handling; (2) isotopic gamma scans; (3) fission gas analyses; (4) ceramography of the fuel and metallography of the cladding; (5) special fuel studies involving analytical transmission electron microscopy (AEM); (6) calculated nuclide inventories and radioactivities in the fuel and cladding; and (7) radiochemical analyses of the fuel and cladding. Additional analyses of the fuel are being conducted and will be included in planned revisions of this report.

  12. Installing Mechanics of Granular Materials (MGM) experiment Test Cell

    Science.gov (United States)

    1996-01-01

    Astronaut Jay Apt installs Mechanics of Granular Materials (MGM0 test cell on STS-79. Sand and soil grains have faces that can cause friction as they roll and slide against each other, or even cause sticking and form small voids between grains. This complex behavior can cause soil to behave like a liquid under certain conditions such as earthquakes or when powders are handled in industrial processes. MGM experiments aboard the Space Shuttle use the microgravity of space to simulate this behavior under conditions that carnot be achieved in laboratory tests on Earth. MGM is shedding light on the behavior of fine-grain materials under low effective stresses. Applications include earthquake engineering, granular flow technologies (such as powder feed systems for pharmaceuticals and fertilizers), and terrestrial and planetary geology. Nine MGM specimens have flown on two Space Shuttle flights. Another three are scheduled to fly on STS-107. The principal investigator is Stein Sture of the University of Colorado at Boulder. (Credit: NASA/John Space Center).

  13. Quality Assurance Protocol for AFCI Advanced Structural Materials Testing

    International Nuclear Information System (INIS)

    Busby, Jeremy T.

    2009-01-01

    The objective of this letter is to inform you of recent progress on the development of advanced structural materials in support of advanced fast reactors and AFCI. As you know, the alloy development effort has been initiated in recent months with the procurement of adequate quantities of the NF616 and HT-UPS alloys. As the test alloys become available in the coming days, mechanical testing, evaluation of optimizing treatments, and screening of environmental effects will be possible at a larger scale. It is therefore important to establish proper quality assurance protocols for this testing effort in a timely manner to ensure high technical quality throughout testing. A properly implemented quality assurance effort will also enable preliminary data taken in this effort to be qualified as NQA-1 during any subsequent licensing discussions for an advanced design or actual prototype. The objective of this report is to describe the quality assurance protocols that will be used for this effort. An essential first step in evaluating quality protocols is assessing the end use of the data. Currently, the advanced structural materials effort is part of a long-range, basic research and development effort and not, as yet, involved in licensing discussions for a specific reactor design. After consultation with Mark Vance (an ORNL QA expert) and based on the recently-issued AFCI QA requirements, the application of NQA-1 quality requirements will follow the guidance provided in Part IV, Subpart 4.2 of the NQA-1 standard (Guidance on Graded Application of QA for Nuclear-Related Research and Development). This guidance mandates the application of sound scientific methodology and a robust peer review process in all phases, allowing for the data to be qualified for use even if the programmatic mission changes to include licensing discussions of a specific design or prototype. ORNL has previously implemented a QA program dedicated to GNEP activities and based on an appropriately graded

  14. Quality Assurance Protocol for AFCI Advanced Structural Materials Testing

    Energy Technology Data Exchange (ETDEWEB)

    Busby, Jeremy T [ORNL

    2009-05-01

    The objective of this letter is to inform you of recent progress on the development of advanced structural materials in support of advanced fast reactors and AFCI. As you know, the alloy development effort has been initiated in recent months with the procurement of adequate quantities of the NF616 and HT-UPS alloys. As the test alloys become available in the coming days, mechanical testing, evaluation of optimizing treatments, and screening of environmental effects will be possible at a larger scale. It is therefore important to establish proper quality assurance protocols for this testing effort in a timely manner to ensure high technical quality throughout testing. A properly implemented quality assurance effort will also enable preliminary data taken in this effort to be qualified as NQA-1 during any subsequent licensing discussions for an advanced design or actual prototype. The objective of this report is to describe the quality assurance protocols that will be used for this effort. An essential first step in evaluating quality protocols is assessing the end use of the data. Currently, the advanced structural materials effort is part of a long-range, basic research and development effort and not, as yet, involved in licensing discussions for a specific reactor design. After consultation with Mark Vance (an ORNL QA expert) and based on the recently-issued AFCI QA requirements, the application of NQA-1 quality requirements will follow the guidance provided in Part IV, Subpart 4.2 of the NQA-1 standard (Guidance on Graded Application of QA for Nuclear-Related Research and Development). This guidance mandates the application of sound scientific methodology and a robust peer review process in all phases, allowing for the data to be qualified for use even if the programmatic mission changes to include licensing discussions of a specific design or prototype. ORNL has previously implemented a QA program dedicated to GNEP activities and based on an appropriately graded

  15. Biomedical technology

    CERN Document Server

    Wriggers, Peter

    2015-01-01

    During the last years computational methods lead to new approaches that can be applied within medical practice. Based on the tremendous advances in medical imaging and high-performance computing, virtual testing is able to help in medical decision processes or implant designs. Current challenges in medicine and engineering are related to the application of computational methods to clinical medicine and the study of biological systems at different scales. Additionally manufacturers will be able to use computational tools and methods to predict the performance of their medical devices in virtual patients. The physical and animal testing procedures could be reduced by virtual prototyping of medical devices. Here simulations can enhance the performance of alternate device designs for a range of virtual patients. This will lead to a refinement of designs and to safer products. This book summarizes different aspects of approaches to enhance function, production, initialization and complications of different types o...

  16. 1000–ton testing machine for cyclic fatigue tests of materials at liquid nitrogen temperatures

    International Nuclear Information System (INIS)

    Khitruk, A. A.; Klimchenko, Yu. A.; Kovalchuk, O. A.; Marushin, E. L.; Mednikov, A. A.; Nasluzov, S. N.; Privalova, E. K.; Rodin, I. Yu.; Stepanov, D. B.; Sukhanova, M. V.

    2014-01-01

    One of the main tasks of superconductive magnets R and D is to determine the mechanical and fatigue properties of structural materials and the critical design elements in the cryogenic temperature range. This paper describes a new facility built based on the industrial 1000-ton (10 MN) testing machine Schenk PC10.0S. Special equipment was developed to provide the mechanical and cyclic tensile fatigue tests of large-scale samples at the liquid nitrogen temperature and in a given load range. The main feature of the developed testing machine is the cryostat, in which the device converting a standard compression force of the testing machine to the tensile force affected at the test object is placed. The control system provides the remote control of the test and obtaining, processing and presentation of test data. As an example of the testing machine operation the test program and test results of the cyclic tensile fatigue tests of fullscale helium inlet sample of the PF1 coil ITER are presented

  17. Alternative buffer material. Status of the ongoing laboratory investigation of reference materials and test package 1

    International Nuclear Information System (INIS)

    Svensson, Daniel; Dueck, Ann; Nilsson, Ulf; Olsson, Siv; Sanden, Torbjoern; Lydmark, Sara; Jaegerwall, Sara; Pedersen, Karsten; Hansen, Staffan

    2011-07-01

    Bentonite clay is part of the Swedish KBS-3 design of final repositories for high level radioactive waste. Wyoming bentonite with the commercial name MX-80 (American Colloid Co) has long been the reference for buffer material in the KBS-3 concept. Extending the knowledge base of alternative buffer materials will make it possible to optimize regarding safety, availability and cost. For this reason the field experiment Alternative Buffer Material (ABM) was started at Aespoe Hard Rock Laboratory during 2006. The experiment includes three medium-scale test packages, each consisting of a central steel tube with heaters, and a buffer of compacted clay. Eleven different clays were chosen for the buffers to examine effects of smectite content, interlayer cations and overall iron content. Also bentonite pellets with and without additional quartz are being tested. The buffer in package 1 had been subjected to wetting by formation water and heating for more than two years (at 130 deg C for ∼ 1 year) when it was retrieved and analyzed. The main purposes of the project were to characterise the clays with respect to hydro-mechanical properties, mineralogy and chemical composition and to identify any differences in behaviour or long term stability. The diversity of clays and the heater of steel also make the experiment suitable for studies of iron-bentonite interactions. This report concerns the work accomplished up to now and is not to be treated as any final report of the project

  18. Alternative buffer material. Status of the ongoing laboratory investigation of reference materials and test package 1

    Energy Technology Data Exchange (ETDEWEB)

    Svensson, Daniel [Swedish Nuclear Fuel and Waste Management Co., Stockholm (Sweden); Dueck, Ann; Nilsson, Ulf; Olsson, Siv; Sanden, Torbjoern [Clay Technology AB, Lund (Sweden); Lydmark, Sara; Jaegerwall, Sara; Pedersen, Karsten [Microbial Analytics Sweden AB, Moelnlycke (Sweden); Hansen, Staffan [LTH Lund Univ., Lund (Sweden)

    2011-07-15

    Bentonite clay is part of the Swedish KBS-3 design of final repositories for high level radioactive waste. Wyoming bentonite with the commercial name MX-80 (American Colloid Co) has long been the reference for buffer material in the KBS-3 concept. Extending the knowledge base of alternative buffer materials will make it possible to optimize regarding safety, availability and cost. For this reason the field experiment Alternative Buffer Material (ABM) was started at Aespoe Hard Rock Laboratory during 2006. The experiment includes three medium-scale test packages, each consisting of a central steel tube with heaters, and a buffer of compacted clay. Eleven different clays were chosen for the buffers to examine effects of smectite content, interlayer cations and overall iron content. Also bentonite pellets with and without additional quartz are being tested. The buffer in package 1 had been subjected to wetting by formation water and heating for more than two years (at 130 deg C for {approx} 1 year) when it was retrieved and analyzed. The main purposes of the project were to characterise the clays with respect to hydro-mechanical properties, mineralogy and chemical composition and to identify any differences in behaviour or long term stability. The diversity of clays and the heater of steel also make the experiment suitable for studies of iron-bentonite interactions. This report concerns the work accomplished up to now and is not to be treated as any final report of the project.

  19. Synthesis of functional materials by radiation and qualification testing of organic materials in nuclear power plant

    International Nuclear Information System (INIS)

    Nho, Young Chang; Kim, Ki Yup; Kang, Phil Hyun and others; Jun, Hong Jae; Suh, Dong Hak; Lee, Young Moo; Min, Byung Kak; Bae, You Han

    2003-05-01

    The radiation crosslinking and grafting can be easily adjusted and is easily reproducible by controlling the radiation dose. These studies aim to develop new biomaterials such as covering for burns and wound, and controlled release of drug. A radiation technology was used to develop PTC materials useful in devices that limit electric fault currents. Radiation-curing of fiber-matrix composites is a promising application. There are a number of advantages to radiation curing of composites, compared with conventional thermal processing. Radiation curing at ambient temperature allows tighter control of part dimensions, and elimination of internal stresses which otherwise occur on cooling and which reduce material strength. These studies involved radiation curing of epoxy resins with various fibers and filler for structural application for aerospace and sport goods. The chain scission is the basis of other radiation treatments aimed at enhancing processing characteristics of polymers. These studies aim to make PTFE powder from PTFE scrap using the radiation degradation which allows incorporation of the material into coatings, inks etc. Low density polyethylene, crosslinked polyethylene, ethylene propylene rubber, and acrylonitrile butadiene rubber as cable insulating, seathing and sealing materials were irradiated for the accelerated ageing tests. Degradation was investigated by measuring dielectric analysis, thermogravimetric analysis, and dynamic mechanical analysis. Dielectric tanδ, storage modulus and loss modulus were increased with irradiation doses. However, decomposition temperature decreased with irradiation doses

  20. Testing integrated behavioural and biomedical models of activity and activity limitations in a population-based sample.

    Science.gov (United States)

    Dixon, Diane; Johnston, Marie; Elliott, Alison; Hannaford, Phil

    2012-01-01

    The predictive utility of an integrated model of disability is tested. The integrated model incorporates an impairment based model (International Classification of Functioning, Disability and Health (ICF)) and the behavioural models. Community dwelling adults (n = 628) completed a postal questionnaire measuring the integrated model. The ability of the model to predict disability in the form of activity limitations (ALs) and walking, in the full community sample and in respondents reporting chronic pain was tested. In both the community and chronic pain samples each version of the integrated model explained a majority (55%-67%) of the variance in ALs but only 11%-29% of the variance in walking behaviour (WB). Impairment directly predicted ALs but did not directly predict WB. Control related cognitions were direct predictors, and mediators, of the relationship between bodily impairment and both ALs and WB. In addition, intentions and outcome expectancies predicted WB. Self-efficacy (SE) was the most consistent predictor of both ALs and WB. An integrated model which combines psychological constructs and impairment is required for an adequate understanding of ALs. By contrast, behavioural models, but not degree of impairment, are necessary to explain activity levels.

  1. Aerogel Hybrid Composite Materials: Designs and Testing for Multifunctional Applications

    Science.gov (United States)

    Williams, Martha K.; Fesmire, James E.

    2016-01-01

    This webinar will introduce the broad spectrum of aerogel composites and their diverse performance properties such as reduced heat transfer to energy storage, and expands specifically on the aerogel/fiber laminate systems and testing methodologies. The multi-functional laminate composite system, AeroFiber, and its construction is designed by varying the type of fiber (e.g. polyester, carbon, Kevlar®, Spectra® or Innegral(TradeMark) and combinations thereof), the aerogel panel type and thickness, and overall layup configuration. The combination and design of materials may be customized and tailored to achieve a range of desired properties in the resulting laminate system. Multi-functional properties include structural strength, impact resistance, reduction in heat transfer, increased fire resistance, mechanical energy absorption, and acoustic energy dampening. Applications include aerospace, aircraft, automotive, boating, building and construction, lightweight portable structures, liquefied natural gas, cryogenics, transportation and energy, sporting equipment, and military protective gear industries.

  2. The materials irradiation experiment for testing plasma facing materials at fusion relevant conditions

    Energy Technology Data Exchange (ETDEWEB)

    Garrison, L. M., E-mail: garrisonlm@ornl.gov; Egle, B. J. [Oak Ridge National Laboratory, 1 Bethel Valley Road, Oak Ridge, Tennessee 37831 (United States); Fusion Technology Institute, University of Wisconsin-Madison, 1500 Engineering Drive, Madison, Wisconsin 53706 (United States); Zenobia, S. J.; Kulcinski, G. L.; Santarius, J. F. [Fusion Technology Institute, University of Wisconsin-Madison, 1500 Engineering Drive, Madison, Wisconsin 53706 (United States)

    2016-08-15

    The Materials Irradiation Experiment (MITE-E) was constructed at the University of Wisconsin-Madison Inertial Electrostatic Confinement Laboratory to test materials for potential use as plasma-facing materials (PFMs) in fusion reactors. PFMs in fusion reactors will be bombarded with x-rays, neutrons, and ions of hydrogen and helium. More needs to be understood about the interactions between the plasma and the materials to validate their use for fusion reactors. The MITE-E simulates some of the fusion reactor conditions by holding samples at temperatures up to 1000 °C while irradiating them with helium or deuterium ions with energies from 10 to 150 keV. The ion gun can irradiate the samples with ion currents of 20 μA–500 μA; the typical current used is 72 μA, which is an average flux of 9 × 10{sup 14} ions/(cm{sup 2} s). The ion gun uses electrostatic lenses to extract and shape the ion beam. A variable power (1-20 W), steady-state, Nd:YAG laser provides additional heating to maintain a constant sample temperature during irradiations. The ion beam current reaching the sample is directly measured and monitored in real-time during irradiations. The ion beam profile has been investigated using a copper sample sputtering experiment. The MITE-E has successfully been used to irradiate polycrystalline and single crystal tungsten samples with helium ions and will continue to be a source of important data for plasma interactions with materials.

  3. Potential mirror concepts for radiation testing of fusion reactor materials

    International Nuclear Information System (INIS)

    Miley, G.H.

    1977-01-01

    Studies under the University of Illinois PROMETHEUS (Plasma Reactor Optimized for Materials Experimentation for Thermonuclear Energy Usage) project are described that started in 1971 with the realization that a practical fusion-plasma neutron source was feasible with a net-power input (rather than production). The basic objectives were similar to those in later FERF (Fusion Engineering Research Facility) studies: namely, to maximize the neutron flux and usable experimental volume; to include the flexibility to handle a variety of both materials and engineering experiments; to minimize capital and operating costs; and to utilize near- term technology. The PROMETHEUS design provides a neutron flux of approximately 5x10 14 n/cm 2 s by injection of approximately 30 MW of neutral-beams into a 20 cm radius mirror-confined plasma. Charge-exchange bombardment of the first wall is viewed as a key problem in the design and is discussed in some detail. To gain yet higher neutron fluxes for accelerated testing, two alternate designs have been studied: a 'Twin-beam' injection device and a field reversed mirror concept. The latter potentially offers fluxes approaching 10 16 n/cm 2 s but involves more speculative technology. (Auth.)

  4. ISO test survey on material influence in dimensional computed tomography

    Directory of Open Access Journals (Sweden)

    Markus Bartscher

    2016-11-01

    Full Text Available ISO/TC 213/WG 10 is responsible for creating international standards (series ISO 10360 for the acceptance testing of coordinate measuring systems (CMSs. A current topic is creating a future part of ISO 10360 for CMSs using dimensional computed tomography (CT. The discussion is focussed on how to include material thickness influence in acceptance testing. ISO/TC 213/WG 10 decided to perform an experimental survey to study this topic. This ISO test survey covers several national metrology institutes and manufacturers. Reference standards under study made of aluminium are two step cylinders provided by the National Metrology Institute of Japan (NMIJ, and two hole plates provided by the Physikalisch-Technische Bundesanstalt (PTB, Germany. To check for residual errors of CT-based CMSs, additional reference standards may be measured by participants. This report details results and experiences of the participant PTB. PTB applied scaling reference measurements of a multi-sphere standard and a printed circuit board as additional reference standards, i.e. in addition to hole plate and step cylinder measurements, respectively. Measurements were performed in mid 2015 using the PTB dimensional CT system (Nikon Metrology MCT225. In this contribution, special focus is placed on the interpretation of the results and the consequences of a potential testing regime. This text does not directly describe an existing ISO standard nor a published or intended ISO standard draft. It is intended to contribute to the research of influence parameters which are relevant for a possible future part of ISO 10360 for the case of CT-based CMS (which is assumed to be part 11.

  5. Standard Test Method for Oxyacetylene Ablation Testing of Thermal Insulation Materials

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2008-01-01

    1.1 This test method covers the screening of ablative materials to determine the relative thermal insulation effectiveness when tested as a flat panel in an environment of a steady flow of hot gas provided by an oxyacetylene burner. 1.2 This test method should be used to measure and describe the properties of materials, products, or assemblies in response to heat and flame under controlled laboratory conditions and should not be used to describe or appraise the fire hazard of materials, products, or assemblies under actual fire conditions. However, results of this test method may be used as elements of a fire risk assessment which takes into account all of the factors which are pertinent to an assessment of the fire hazard of a particular end use. 1.3 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limi...

  6. Rethinking 3R strategies: Digging deeper into AnimalTestInfo promotes transparency in in vivo biomedical research.

    Science.gov (United States)

    Bert, Bettina; Dörendahl, Antje; Leich, Nora; Vietze, Julia; Steinfath, Matthias; Chmielewska, Justyna; Hensel, Andreas; Grune, Barbara; Schönfelder, Gilbert

    2017-12-01

    In the European Union (EU), animal welfare is seen as a matter of great importance. However, with respect to animal experimentation, European citizens feel quite uninformed. The European Directive 2010/63/EU for the protection of laboratory animals aims for greater transparency and requires that a comprehensible, nontechnical summary (NTS) of each authorised research project involving animals is published by the respective Member State. However, the NTSs remain sleeping beauties if their contents are not easily and systematically accessible. The German web-based NTS database AnimalTestInfo is a unique channel for scientists to communicate their work, and provides the opportunity for large-scale analyses of planned animal studies to inform researchers and the public. For an in-depth meta-analysis, we classified the duly completed NTSs submitted to AnimalTestInfo in 2014 and 2015 according to the International Classification of Diseases and Related Health Problems (ICD) system. Indexing the NTSs with ICD codes provided a fine-grained overview of the prospective uses of experimental animals. Using this approach, transparency, especially for highly controversial animal research involving, for example, nonhuman primates, is fostered, as it enables pinpointing the envisaged beneficiary down to the level of the addressed disease. Moreover, research areas with many planned projects involving animals can be specified in detail. The development of 3R (replacement, reduction, and refinement) measures in these research areas may be most efficient, as a large number of experimental animals would benefit from it. Indexing NTSs with ICD codes can support governments and funding agencies in advancing target-oriented funding of 3R research. Data drawn from NTSs can provide a basis for the development, validation, and implementation of directed 3R strategies as well as guidance for rethinking the role of animal research models.

  7. Rethinking 3R strategies: Digging deeper into AnimalTestInfo promotes transparency in in vivo biomedical research.

    Directory of Open Access Journals (Sweden)

    Bettina Bert

    2017-12-01

    Full Text Available In the European Union (EU, animal welfare is seen as a matter of great importance. However, with respect to animal experimentation, European citizens feel quite uninformed. The European Directive 2010/63/EU for the protection of laboratory animals aims for greater transparency and requires that a comprehensible, nontechnical summary (NTS of each authorised research project involving animals is published by the respective Member State. However, the NTSs remain sleeping beauties if their contents are not easily and systematically accessible. The German web-based NTS database AnimalTestInfo is a unique channel for scientists to communicate their work, and provides the opportunity for large-scale analyses of planned animal studies to inform researchers and the public. For an in-depth meta-analysis, we classified the duly completed NTSs submitted to AnimalTestInfo in 2014 and 2015 according to the International Classification of Diseases and Related Health Problems (ICD system. Indexing the NTSs with ICD codes provided a fine-grained overview of the prospective uses of experimental animals. Using this approach, transparency, especially for highly controversial animal research involving, for example, nonhuman primates, is fostered, as it enables pinpointing the envisaged beneficiary down to the level of the addressed disease. Moreover, research areas with many planned projects involving animals can be specified in detail. The development of 3R (replacement, reduction, and refinement measures in these research areas may be most efficient, as a large number of experimental animals would benefit from it. Indexing NTSs with ICD codes can support governments and funding agencies in advancing target-oriented funding of 3R research. Data drawn from NTSs can provide a basis for the development, validation, and implementation of directed 3R strategies as well as guidance for rethinking the role of animal research models.

  8. Rethinking 3R strategies: Digging deeper into AnimalTestInfo promotes transparency in in vivo biomedical research

    Science.gov (United States)

    Dörendahl, Antje; Leich, Nora; Vietze, Julia; Steinfath, Matthias; Chmielewska, Justyna; Hensel, Andreas; Grune, Barbara; Schönfelder, Gilbert

    2017-01-01

    In the European Union (EU), animal welfare is seen as a matter of great importance. However, with respect to animal experimentation, European citizens feel quite uninformed. The European Directive 2010/63/EU for the protection of laboratory animals aims for greater transparency and requires that a comprehensible, nontechnical summary (NTS) of each authorised research project involving animals is published by the respective Member State. However, the NTSs remain sleeping beauties if their contents are not easily and systematically accessible. The German web-based NTS database AnimalTestInfo is a unique channel for scientists to communicate their work, and provides the opportunity for large-scale analyses of planned animal studies to inform researchers and the public. For an in-depth meta-analysis, we classified the duly completed NTSs submitted to AnimalTestInfo in 2014 and 2015 according to the International Classification of Diseases and Related Health Problems (ICD) system. Indexing the NTSs with ICD codes provided a fine-grained overview of the prospective uses of experimental animals. Using this approach, transparency, especially for highly controversial animal research involving, for example, nonhuman primates, is fostered, as it enables pinpointing the envisaged beneficiary down to the level of the addressed disease. Moreover, research areas with many planned projects involving animals can be specified in detail. The development of 3R (replacement, reduction, and refinement) measures in these research areas may be most efficient, as a large number of experimental animals would benefit from it. Indexing NTSs with ICD codes can support governments and funding agencies in advancing target-oriented funding of 3R research. Data drawn from NTSs can provide a basis for the development, validation, and implementation of directed 3R strategies as well as guidance for rethinking the role of animal research models. PMID:29240762

  9. 46 CFR 54.05-10 - Certification of material toughness tests.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Certification of material toughness tests. 54.05-10... PRESSURE VESSELS Toughness Tests § 54.05-10 Certification of material toughness tests. (a) Plate material..., toughness qualifications shall be determined by the Commandant based on material, chemical, and mechanical...

  10. Using crowdsourcing technology for testing multilingual public health promotion materials.

    Science.gov (United States)

    Turner, Anne M; Kirchhoff, Katrin; Capurro, Daniel

    2012-06-04

    Effective communication of public health messages is a key strategy for health promotion by public health agencies. Creating effective health promotion materials requires careful message design and feedback from representatives of target populations. This is particularly true when the target audiences are hard to reach as limited English proficiency groups. Traditional methods of soliciting feedback--such as focus groups and convenience sample interviews--are expensive and time consuming. As a result, adequate feedback from target populations is often insufficient due to the time and resource constraints characteristic to public health. To describe a pilot study investigating the use of crowdsourcing technology as a method to gather rapid and relevant feedback on the design of health promotion messages for oral health. Our goal was to better describe the demographics of participants responding to a crowdsourcing survey and to test whether crowdsourcing could be used to gather feedback from English-speaking and Spanish-speaking participants in a short period of time and at relatively low costs. We developed health promotion materials on pediatric dental health issues in four different formats and in two languages (English and Spanish). We then designed an online survey to elicit feedback on format preferences and made it available in both languages via the Amazon Mechanical Turk crowdsourcing platform. We surveyed 236 native English-speaking and 163 native Spanish-speaking participants in less than 12 days, at a cost of US $374. Overall, Spanish-speaking participants originated from a wider distribution of countries than the overall Latino population in the United States. Most participants were in the 18- to 29-year age range and had some college or graduate education. Participants provided valuable input for the health promotion material design. Our results indicate that crowdsourcing can be an effective method for recruiting and gaining feedback from English

  11. Project accent: graphite irradiated creep in a materials test reactor

    International Nuclear Information System (INIS)

    Brooking, M.

    2014-01-01

    Atkins manages a pioneering programme of irradiation experiments for EDF Energy. One of these projects is Project ACCENT, designed to obtain evidence of a beneficial physical property of the graphite, which may extend the life of the Advanced Gas-cooled Reactors (AGRs). The project team combines the in-house experience of EDF Energy with two supplier organisations (providing the material test reactors and testing facilities) and supporting consultancies (Atkins and an independent technical expert). This paper describes: - Brief summary of the Project; - Discussion of the challenges faced by the Project; and - Conclusion elaborating on the aims of the Project. These challenging experiments use bespoke technology and both un-irradiated (virgin) and irradiated AGR graphite. The results will help to better understand graphite irradiation-induced creep (or stress modified dimensional change) properties and therefore more accurately determine lifetime and safe operating envelopes of the AGRs. The first round of irradiation has been completed, with a second round about to commence. This is a key step to realising the full lifetime ambition for AGRs, demonstrating the relaxation of stresses within the graphite bricks. (authors)

  12. Biomechanical testing and material characterization for the rat large intestine: regional dependence of material parameters.

    Science.gov (United States)

    Sokolis, Dimitrios P; Orfanidis, Ioannis K; Peroulis, Michalis

    2011-12-01

    The function of the large bowel is to absorb water from the remaining indigestible food matter and subsequently pass useless waste material from the body, but there has been only a small amount of data in the literature on its biomechanical characteristics that would facilitate our understanding of its transport function. Our study aims to fill this gap by affording comprehensive inflation/extension data of intestinal segments from distinct areas, spanning a physiologically relevant deformation range (100-130% axial stretches and 0-15 mmHg lumen pressures). These data were characterized by the Fung-type exponential model in the thick-walled setting, showing reasonable agreement, i.e. root-mean-square error ~30%. Based on optimized material parameters, i.e. a(1)testing and material characterization results for the large intestine of healthy young animals are expected to aid in comprehending the adaptation/remodeling that occurs with ageing, pathological conditions and surgical procedures, as well as for the development of suitable biomaterials for replacement.

  13. Thermo-hydro-mechanical tests of buffer material

    International Nuclear Information System (INIS)

    Pintado, X.; Hassan, Md. M.; Martikainen, J.

    2013-10-01

    MX-80 bentonite is the reference clay material for the buffer component planned to be used in the deep geological repository for the disposal of spent nuclear fuel in Finland. The buffer presents complex thermo-hydro-mechanical behavior which is modeled with different constitutive models for heat flow, water flow and stress-strain evolution in the buffer. Thermo, hydro and mechanical models need parameters to evaluate the THM-behavior. These modeling parameters were determined by performing series of laboratory experiments as follows: Water retention curve tests were performed on compacted bentonite samples, encompassing a range of initial dry density values from 1397 to 1718 kg/m 3 as the initial water content was around of 5-8 %. The water retention curve was determined by imposing different suctions to the samples and the suctions were then checked using capacitive hygrometer and chilled mirror psychrometer. Oedometer tests were performed on compacted bentonite samples, encompassing a range of initial dry density values from 1590 to 1750 kg/m 3 as the initial water content was around of 6 %. Samples were saturated with tap water, 35 or 70 g/L salt solutions. Infiltration tests were performed on compacted unsaturated bentonite samples, encompassing a range of initial dry density values from 1400 to 1720 kg/m 3 as the initial water content was approximately between 4-7 %. Samples were saturated with tap water, 0.87, 35 or 70 g/L salt solutions. Tortuosity tests were performed on bentonite samples, encompassing a range of dry density values from 1460 to 1750 kg/m 3 and the degree of saturation varied between 33-93 %. Thermal conductivity tests were performed on compacted bentonite samples, encompassing a range of dry density values from 1545 to 1715 kg/m 3 and the degree of saturation varied between 31-88 %. The measurement was performed using a thermal needle probe. The general trend of all analyzed parameters was as expected when dry density, water content, and

  14. Solid State Reaction Synthesis of Si-HA as Potential Biomedical Material: An Endeavor to Enhance the Added Value of Indonesian Mineral Resources

    Science.gov (United States)

    Hartatiek; Yudyanto; Ratnasari, S. D.; Windari, R. Y.; Hidayat, N.

    2017-05-01

    In recent years, one of the most prominently investigated materials is hydroxyapatite (HA). It is because of its excellent properties for medical applications, essentially related to orthopedic. Also, the introduction of other materials to HA becomes another research focus of many leading scientists. In this present study, silicon with various concentrations was introduced, by means of solid state reaction route, to HA forming Si-HA. The crystal structure properties of the as-prepared samples were evaluated by X-ray diffractometer (XRD). Fourier Transform Infra Red (FTIR) spectroscopy data collection and analysis were done to investigate the functional groups within the samples. The microstructural characteristics as well as elemental mapping of the samples were captured by scanning electron microscopy and energy dispersive x-ray spectroscopy (SEM-EDX). Vickers hardness test was also conducted to investigate the hardness properties of the samples. Furthermore, in vitro characterization-based bio resorbability of the samples in a simulated body fluid were also described. This study revealed that Indonesian limestone can be utilized as the raw material for synthesizing HA. The silicon has been successfully incorporated into phosphate site of the HA crystal. Conclusively, the Si-HA reported in this study shows good bioresorbability characteristic.

  15. Gold Nanocages for Biomedical Applications**

    OpenAIRE

    Skrabalak, Sara E.; Chen, Jingyi; Au, Leslie; Lu, Xianmao; Li, Xingde; Xia, Younan

    2007-01-01

    Nanostructured materials provide a promising platform for early cancer detection and treatment. Here we highlight recent advances in the synthesis and use of Au nanocages for such biomedical applications. Gold nanocages represent a novel class of nanostructures, which can be prepared via a remarkably simple route based on the galvanic replacement reaction between Ag nanocubes and HAuCl4. The Au nanocages have a tunable surface plasmon resonance peak that extends into the near-infrared, where ...

  16. The technology development for surveillance test of RPV materials 2

    International Nuclear Information System (INIS)

    Chang, Kee Ok; Lee, Sam Lai; Kim, Byoung Chul; Choi, Sun Pil; Choi, Kwen Jai

    1998-12-01

    Irradiation-induced changes in mechanical properties and magnetic parameters were measured and compared to explore possible correlations for Mn-Mo-Ni low alloy steel surveillance specimens which were irradiated to a neutron fluence of 2.4 x 10 1 9n/cm 2 (E≥1.0 MeV) in a typical pressurized water reactor environment at about 288 deg C. For mechanical property parameters, microvickers hardness, tensile and Charpy impact test were performed and Barkhausen Noise(BN) amplitude, coercivity, maximum induction were measured for magnetic parameters, respectively. Results of mechanical property measurements showed an increase in yield and tensil strength, microvickers hardness 41J indexed RT NDT and a decrease in upper shelf energy irrespective of base and weld metals. In the case of magnetic measurements, it is found that magnetic remanence, BN amplitude, BN energy have dropped significantly but coercivity has increased rapidly after irradiation. For isothermally heat treated condition of irradiated specimen, BN energy has increased while Vickers microhardness has decreased. Results of BNE and Vickers microhardness are reversed to the results on irradiated condition. All these consistent changes in magnetic parameter and Vickers microhardness measurement, which are thought to be resulted from the interaction between irradiation-induced defects and dislocation, and magnetic domain, respectively, show a possibility that magnetic measurement may be used to the evaluation of material degradation and recovery due to neutron irradiation and heat treatment, respectively, if a relevant large database is prepared. (author). 49 refs., 7 tabs., 23 figs

  17. Bleed water testing program for controlled low strength material

    International Nuclear Information System (INIS)

    Langton, C.A.

    1996-01-01

    Bleed water measurements for two Controlled Low Strength Material (CLSM) mixes were conducted to provide engineering data for the Tank 20F closure activities. CLSM Mix 1 contained 150 pounds of cement per cubic yard whereas CLSM Mix 2 contained 50 pounds per cub yard. SRS currently used CLSM Mix 2 for various applications. Bleed water percentages and generation rates were measured along with flow and compressive strength. This information will be used to select a mix design for the Tank 20F closure activities and to establish the engineering requirements, such as, lift height, time required between lifts and quantity of bleed water to be removed from the tank during the placement activities. Mix 1 is recommended for placement within Tank 20F because it has better flow characteristics, less segregation, lower percentage of bleed water and slightly higher strength. Optimization of Mix 1 was beyond the scope of this study. However, further testing of thickening additives, such as clays (bentonite), sodium silicate or fine silicas maybe useful for decreasing or eliminating bleed water

  18. Materials Testing: Why Don't Those Bats Break? Resources in Technology.

    Science.gov (United States)

    Jacobs, James A.

    1995-01-01

    Describes high-tech methods of materials testing and organizations that perform it. Suggests that materials testing is an ideal example of the integration of mathematics, science, and technology. (SK)

  19. Semiconducting silicon nanowires for biomedical applications

    CERN Document Server

    Coffer, JL

    2014-01-01

    Biomedical applications have benefited greatly from the increasing interest and research into semiconducting silicon nanowires. Semiconducting Silicon Nanowires for Biomedical Applications reviews the fabrication, properties, and applications of this emerging material. The book begins by reviewing the basics, as well as the growth, characterization, biocompatibility, and surface modification, of semiconducting silicon nanowires. It goes on to focus on silicon nanowires for tissue engineering and delivery applications, including cellular binding and internalization, orthopedic tissue scaffol

  20. Fundamental of biomedical engineering

    CERN Document Server

    Sawhney, GS

    2007-01-01

    About the Book: A well set out textbook explains the fundamentals of biomedical engineering in the areas of biomechanics, biofluid flow, biomaterials, bioinstrumentation and use of computing in biomedical engineering. All these subjects form a basic part of an engineer''s education. The text is admirably suited to meet the needs of the students of mechanical engineering, opting for the elective of Biomedical Engineering. Coverage of bioinstrumentation, biomaterials and computing for biomedical engineers can meet the needs of the students of Electronic & Communication, Electronic & Instrumenta

  1. Biomedical engineering principles

    CERN Document Server

    Ritter, Arthur B; Valdevit, Antonio; Ascione, Alfred N

    2011-01-01

    Introduction: Modeling of Physiological ProcessesCell Physiology and TransportPrinciples and Biomedical Applications of HemodynamicsA Systems Approach to PhysiologyThe Cardiovascular SystemBiomedical Signal ProcessingSignal Acquisition and ProcessingTechniques for Physiological Signal ProcessingExamples of Physiological Signal ProcessingPrinciples of BiomechanicsPractical Applications of BiomechanicsBiomaterialsPrinciples of Biomedical Capstone DesignUnmet Clinical NeedsEntrepreneurship: Reasons why Most Good Designs Never Get to MarketAn Engineering Solution in Search of a Biomedical Problem

  2. ESP – Data from Restarted Life Tests of Various Silicon Materials

    Energy Technology Data Exchange (ETDEWEB)

    Schneider, Jim

    2010-10-06

    Current funding has allowed the restart of testing of various silicone materials placed in Life Tests or Aging Studies from past efforts. Some of these materials have been in test since 1982, with no testing for approximately 10 years, until funding allowed the restart in FY97. Charts for the various materials at different thickness, compression, and temperature combinations illustrate trends for the load-bearing properties of the materials.

  3. What is materialism? Testing two dominant perspectives on materialism in the marketing literature

    Directory of Open Access Journals (Sweden)

    Manchiraju Srikant

    2015-09-01

    Full Text Available Materialism is defined as the importance an individual attaches to worldly possessions, which has been considered as an important construct in consumer behavior and marketing literature. There are two dominant perspectives on individual materialism in the marketing literature that focus on (1 personality traits or (2 individual personal values. However, several scholars have questioned the aforementioned materialism conceptualizations. Therefore, the present study directly compares the constructs of personality materialism and value materialism. Structural equation modeling was employed to address the following issues: (1 what are the key conceptual dimensions of materialism, (2 how much do they overlap, and (3 what is their discriminant validity in predicting outcomes linked to materialism. We suggest these two dominant perspectives on individual materialism are two distinct constructs, as they shared only 21 percent of common variance. Furthermore, we stress the multi-faceted nature of materialism, with an emphasis on future research directions related to materialism in marketing.

  4. Toxicity of Uranium Adsorbent Materials using the Microtox Toxicity Test

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jiyeon [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Jeters, Robert T. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Gill, Gary A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kuo, Li-Jung [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Bonheyo, George T. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-10-01

    The Marine Sciences Laboratory at the Pacific Northwest National Laboratory evaluated the toxicity of a diverse range of natural and synthetic materials used to extract uranium from seawater. The uranium adsorbent materials are being developed as part of the U. S. Department of Energy, Office of Nuclear Energy, Fuel Resources Program. The goal of this effort was to identify whether deployment of a farm of these materials into the marine environment would have any toxic effects on marine organisms.

  5. Regulatory and performance tests of packages for transporting radioactive materials

    International Nuclear Information System (INIS)

    Itoh, Chihiro

    2003-01-01

    This is a summary of nuclear tests conducted in our institute, including (1) fireproof and pressure tests of an enriched UF 6 transport package, (2) drop, thermal, and pressure tests of a natural UF 6 transport package, (3) drop, thermal, submerge tests of a spent fuel transport cask, and (4) drop, thermal, and submerge tests of a returned high level vitrified waste transport cask. These tests proved that the transport packages meet IAEA's transport requirements with sufficient margins for the safety. (author)

  6. Research reactors for power reactor fuel and materials testing - Studsvik's experience

    International Nuclear Information System (INIS)

    Grounes, M.

    1998-01-01

    Presently Studsvik's R2 test reactor is used for BWR and PWR fuel irradiations at constant power and under transient power conditions. Furthermore tests are performed with defective LWR fuel rods. Tests are also performed on different types of LWR cladding materials and structural materials including post-irradiation testing of materials irradiated at different temperatures and, in some cases, in different water chemistries and on fusion reactor materials. In the past, tests have also been performed on HTGR fuel and FBR fuel and materials under appropriate coolant, temperature and pressure conditions. Fuel tests under development include extremely fast power ramps simulating some reactivity initiated accidents and stored energy (enthalpy) measurements. Materials tests under development include different types of in-pile tests including tests in the INCA (In-Core Autoclave) facility .The present and future demands on the test reactor fuel in all these cases are discussed. (author)

  7. Standard test method for pin-type bearing test of metallic materials

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    1984-01-01

    1.1 This test method covers a pin-type bearing test of metallic materials to determine bearing yield strength and bearing strength. Note 1—The presence of incidental lubricants on the bearing surfaces may significantly lower the value of bearing yield strength obtained by this method. 1.2 Units—The values stated in inch-pound units are to be regarded as standard. The values given in parentheses are mathematical conversions to SI units that are provided for information only and are not considered standard. 1.3 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

  8. Standard test methods for elevated temperature tension tests of metallic materials

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2009-01-01

    1.1 These test methods cover procedure and equipment for the determination of tensile strength, yield strength, elongation, and reduction of area of metallic materials at elevated temperatures. 1.2 Determination of modulus of elasticity and proportional limit are not included. 1.3 Tension tests under conditions of rapid heating or rapid strain rates are not included. 1.4 The values stated in inch-pound units are to be regarded as standard. The values given in parentheses are mathematical conversions to SI units that are provided for information only and are not considered standard. 1.5 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

  9. Reference materials and representative test materials to develop nanoparticle characterization methods: the NanoChOp project case

    Directory of Open Access Journals (Sweden)

    Gert eRoebben

    2015-10-01

    Full Text Available This paper describes the production and characteristics of the nanoparticle test materials prepared for common use in the collaborative research project NanoChOp (Chemical and optical characterisation of nanomaterials in biological systems, in casu suspensions of silica nanoparticles and CdSe/CdS/ZnS quantum dots. This paper is the first to illustrate how to assess whether nanoparticle test materials meet the requirements of a 'reference material' (ISO Guide 30:2015 or rather those of the recently defined category of 'representative test material' (ISO TS 16195:2013. The NanoChOp test materials were investigated with small-angle X-ray scattering (SAXS, dynamic light scattering (DLS and centrifugal liquid sedimentation (CLS to establish whether they complied with the required monomodal particle size distribution. The presence of impurities, aggregates, agglomerates and viable microorganisms in the suspensions was investigated with DLS, CLS, optical and electron microscopy and via plating on nutrient agar. Suitability of surface functionalization was investigated with attenuated total reflection Fourier transform infrared spectrometry (ATR-FTIR and via the capacity of the nanoparticles to be fluorescently labeled or to bind antibodies. Between-unit homogeneity and stability were investigated in terms of particle size and zeta potential. This paper shows that only based on the outcome of a detailed characterization process one can raise the status of a test material to representative test material or reference material, and how this status depends on its intended use.

  10. Reference materials and representative test materials to develop nanoparticle characterization methods: the NanoChOp project case

    Science.gov (United States)

    Roebben, Gert; Kestens, Vikram; Varga, Zoltan; Charoud-Got, Jean; Ramaye, Yannic; Gollwitzer, Christian; Bartczak, Dorota; Geißler, Daniel; Noble, James; Mazoua, Stéphane; Meeus, Nele; Corbisier, Philippe; Palmai, Marcell; Mihály, Judith; Krumrey, Michael; Davies, Julie; Resch-Genger, Ute; Kumarswami, Neelam; Minelli, Caterina; Sikora, Aneta; Goenaga-Infante, Heidi

    2015-10-01

    This paper describes the production and characteristics of the nanoparticle test materials prepared for common use in the collaborative research project NanoChOp (Chemical and optical characterisation of nanomaterials in biological systems), in casu suspensions of silica nanoparticles and CdSe/CdS/ZnS quantum dots. This paper is the first to illustrate how to assess whether nanoparticle test materials meet the requirements of a 'reference material' (ISO Guide 30:2015) or rather those of the recently defined category of 'representative test material' (ISO TS 16195:2013). The NanoChOp test materials were investigated with small-angle X-ray scattering (SAXS), dynamic light scattering (DLS) and centrifugal liquid sedimentation (CLS) to establish whether they complied with the required monomodal particle size distribution. The presence of impurities, aggregates, agglomerates and viable microorganisms in the suspensions was investigated with DLS, CLS, optical and electron microscopy and via plating on nutrient agar. Suitability of surface functionalization was investigated with attenuated total reflection Fourier transform infrared spectrometry (ATR-FTIR) and via the capacity of the nanoparticles to be fluorescently labeled or to bind antibodies. Between-unit homogeneity and stability were investigated in terms of particle size and zeta potential. This paper shows that only based on the outcome of a detailed characterization process one can raise the status of a test material to representative test material or reference material, and how this status depends on its intended use.

  11. Thermal imaging during ballistic testing of armour materials

    NARCIS (Netherlands)

    Carton, E.P.; Roebroeks, G.H.J.J.

    2013-01-01

    During the interaction between a projectile and a target material the kinetic energy of the projectile is transferred into elastic and plastic deformation of both the projectile and target materials. Using a rigid penetrator the loss in kinetic energy is fully converted into energy absorbed by the

  12. Cone calorimeter tests of wood-based decking materials

    Science.gov (United States)

    Robert H. White; Mark A. Dietenberger; Nicole M. Stark

    2007-01-01

    New technologies in building materials have resulted in the use of a wide variety of materials in decks. As part of our effort to address fire concerns in the wildland-urban interface, the Forest Products Laboratory has been examining the fire performance of decking products. In addition to preservative-treated wood, decking products include wood-plastic composites and...

  13. Plant Material Testing: Can we learn from small plots

    Science.gov (United States)

    Choosing appropriate plant materials for a rangeland rehabilitation project is critical for long-term success. The question is what species to seed? We find it is first necessary to define objectives and goals before debating plant material choices. For example, our objective is often to suppress...

  14. Scaling of Core Material in Rubble Mound Breakwater Model Tests

    DEFF Research Database (Denmark)

    Burcharth, H. F.; Liu, Z.; Troch, P.

    1999-01-01

    The permeability of the core material influences armour stability, wave run-up and wave overtopping. The main problem related to the scaling of core materials in models is that the hydraulic gradient and the pore velocity are varying in space and time. This makes it impossible to arrive at a fully...

  15. Innovations in thermoelectric materials research: Compound agglomeration, testing and preselection

    Science.gov (United States)

    Lopez de Cardenas, Hugo Francisco Lopez

    Thermoelectric materials have the capacity to convert a temperature differential into electrical power and vice versa. They will represent the next revolution in alternative energies once their efficiencies are enhanced so they can complement other forms of green energies that depend on sources other than a temperature differential. Progress in materials science depends on the ability to discover new materials to eventually understand them and to finally improve their properties. The work presented here is aimed at dynamizing the screening of materials of thermoelectric interest. The results of this project will enable: theoretical preselection of thermoelectric compounds based on their bandgap and a rapid agglomeration method that does not require melting or sintering. A special interest will be given to Iodine-doped TiSe2 that generated extraordinary results and a new set of equations are proposed to accurately describe the dependence of the power factor and the figure of merit on the intrinsic properties of the materials.

  16. Thermoresponsive Polymers for Biomedical Applications

    Directory of Open Access Journals (Sweden)

    Theoni K. Georgiou

    2011-08-01

    Full Text Available Thermoresponsive polymers are a class of “smart” materials that have the ability to respond to a change in temperature; a property that makes them useful materials in a wide range of applications and consequently attracts much scientific interest. This review focuses mainly on the studies published over the last 10 years on the synthesis and use of thermoresponsive polymers for biomedical applications including drug delivery, tissue engineering and gene delivery. A summary of the main applications is given following the different studies on thermoresponsive polymers which are categorized based on their 3-dimensional structure; hydrogels, interpenetrating networks, micelles, crosslinked micelles, polymersomes, films and particles.

  17. Field tests on migration of TRU-nuclide, (2). Migration test for engineered barrier materials in aerated soil

    International Nuclear Information System (INIS)

    Maeda, Toshikatsu; Tanaka, Tadao; Mukai, Masayuki

    2003-01-01

    Field tests on migration of radionuclides for engineered barrier materials such as bentonite and cementitious materials were performed. The tests were run under both wet conditions with artificial rainfall and dry conditions with natural rainfall. Laboratory experiments such as batch adsorption tests were also conducted to analyze the result of field test. The results of field tests agreed with the predicted moisture conditions and the migration behaviors observed at the laboratory experiment that is reported so far. For bentonite material, the movements of the tracer were calculated using known information such as the results of batch sorption tests and migration mechanism. Comparing the result of field test and calculations, it is suggested that tracer migration behavior in bentonite material in field can be evaluated quantitatively by the known migration mechanism and the results of laboratory experiments such as batch sorption test. (author)

  18. Biomedical applications engineering tasks

    Science.gov (United States)

    Laenger, C. J., Sr.

    1976-01-01

    The engineering tasks performed in response to needs articulated by clinicians are described. Initial contacts were made with these clinician-technology requestors by the Southwest Research Institute NASA Biomedical Applications Team. The basic purpose of the program was to effectively transfer aerospace technology into functional hardware to solve real biomedical problems.

  19. Materials Challenges and Testing for Supply of Energy and Resources

    CERN Document Server

    Bollinghaus, Thomas

    2012-01-01

    One major goal of the World Materials Research Institute Forum - WMRIF is to promote young scientists in the field of materials science and engineering. To enhance the international knowledge exchange between young postdoctoral scientists all over the world, WMRIF meanwhile regularly organizes joint workshops among the member institutes. These workshops also represent an increasingly appreciated platform to get known to each other and to build co-operations. For such workshops, various topics are selected, pointing to future perspectives and challenges in the field of Materials Science and Eng

  20. Corrosion wear fracture of new {beta} biomedical titanium alloys

    Energy Technology Data Exchange (ETDEWEB)

    Niinomi, M.; Fukunaga, K.-I. [Toyohashi Univ. of Technol. (Japan). Dept. of Production Syst. Eng.; Kuroda, D.; Morinaga, M.; Kato, Y.; Yashiro, T.; Suzuki, A.

    1999-05-15

    Metallic materials such as stainless steel, Co-Cr alloy, pure titanium and titanium alloys have been used for surgical implant materials. The {alpha} + {beta} type titanium alloy such as Ti-6Al-4V ELI has been most widely used as an implant material for artificial hip joint and dental implant because of its high strength and excellent corrosion resistance. Toxicity of alloying elements in conventional biomedical titanium alloys like Al and V, and the high modulus of elasticity of these alloy as compared to that of bone have been, however, pointed out [1,2]. New {beta} type titanium alloys composed of non-toxic elements like Nb, Ta, Zr, Mo and Sn with lower moduli of elasticity, greater strength and greater corrosion resistance were, therefore, designed in this study. The friction wear properties of titanium alloys are, however, low as compared to those of other conventional metallic implant materials such as stainless steels and Co-Cr alloy. Tensile tests and friction wear tests in Ringer`s solution were conducted in order to investigate the mechanical properties of designed alloys. The friction wear characteristics of designed alloys and typical conventional biomedical titanium alloys were evaluated using a pin-on-disk type friction wear testing system and measuring the weight loss and width of groove of the specimen. (orig.) 8 refs.

  1. Defect detection in conducting materials using eddy current testing techniques

    Directory of Open Access Journals (Sweden)

    Brauer Hartmut

    2014-01-01

    Full Text Available Lorentz force eddy current testing (LET is a novel nondestructive testing technique which can be applied preferably to the identification of internal defects in nonmagnetic moving conductors. The LET is compared (similar testing conditions with the classical eddy current testing (ECT. Numerical FEM simulations have been performed to analyze the measurements as well as the identification of internal defects in nonmagnetic conductors. The results are compared with measurements to test the feasibility of defect identification. Finally, the use of LET measurements to estimate of the electrical conductors under test are described as well.

  2. The Effect of Testing on the Retention of Coherent and Incoherent Text Material

    Science.gov (United States)

    de Jonge, Mario; Tabbers, Huib K.; Rikers, Remy M. J. P.

    2015-01-01

    Research has shown that testing during learning can enhance the long-term retention of text material. In two experiments, we investigated the testing effect with a fill-in-the-blank test on the retention of text material. In Experiment 1, using a coherent text, we found no retention benefit of testing compared to a restudy (control) condition. In…

  3. Standards for material handling and facilities equipment proofload testing

    Science.gov (United States)

    Bonn, S. P.

    1970-01-01

    Document provides information on verifying the safety of material handling and facilities equipment /MH/FE/, ranging from monorail systems to ladders and non-powered mobile equipment. Seven catagories of MH/FE equipment are defined.

  4. Persistence Testing of Brucella suis on Outdoor Materials ...

    Science.gov (United States)

    Report This report presents the results of an investigation to evaluate Brucella suis persistence on five materials (typically found in the outdoor environment) under various environmental conditions and exposure durations.

  5. Developing Raman spectroscopy for the nondestructive testing of composite materials.

    Science.gov (United States)

    2009-08-01

    The proposed research will develop the application of Raman Spectroscopy as a nondestructive evaluation tool for the condition assessment of carbon fiber composites. Composite materials are increasingly being used in engineered structures and compone...

  6. Comparison and testing of various noise wall materials.

    Science.gov (United States)

    2014-06-01

    Noise barriers are a necessary structure along the highway to protect the local residents from excessive : road noise. There are many different materials from which noise barriers can be constructed. As of 2004, the : most widely used noise barrier m...

  7. Handbook of photonics for biomedical engineering

    CERN Document Server

    Kim, Donghyun; Somekh, Michael

    2017-01-01

    Nanophotonics has emerged rapidly into technological mainstream with the advent and maturity of nanotechnology available in photonics and enabled many new exciting applications in the area of biomedical science and engineering that were unimagined even a few years ago with conventional photonic engineering techniques. Handbook of Nanophotonics in Biomedical Engineering is intended to be a reliable resource to a wealth of information on nanophotonics that can inspire readers by detailing emerging and established possibilities of nanophotonics in biomedical science and engineering applications. This comprehensive reference presents not only the basics of nanophotonics but also explores recent experimental and clinical methods used in biomedical and bioengineering research. Each peer-reviewed chapter of this book discusses fundamental aspects and materials/fabrication issues of nanophotonics, as well as applications in interfaces, cell, tissue, animal studies, and clinical engineering. The organization provides ...

  8. Physical test report to drop test of a 9975 radioactive material shipping packaging

    International Nuclear Information System (INIS)

    Blanton, P.S.

    1997-01-01

    This report presents the drop test results for the 9975 radioactive material shipping package being dropped 30 feet onto a unyielding surface followed by a 40-inch puncture pin drop. The purpose of these drops was to show that the package lid would remain attached to the drum. The 30-foot drop was designed to weaken the lid closure lug while still maintaining maximum extension of the lugs from the drum surface. This was accomplished by angling the drum approximately 30 degrees from horizontal in an inverted position. In this position, the drum was rotated slightly so as not to embed the closure lugs into the drum as a result of the 30-foot drop. It was determined that this orientation would maximize deformation to the closure ring around the closure lug while still maintaining the extension of the lugs from the package surface. The second drop was from 40 inches above a 40-inch tall 6-inch diameter puncture pin. The package was angled 10 degrees from vertical and aligned over the puncture pin to solidly hit the drum lug(s) in an attempt to disengage the lid when dropped.Tests were performed in response to DOE EM-76 review Q5 inquires that questioned the capability of the 9975 drum lid to remain in place under this test sequence. Two packages were dropped utilizing this sequence, a 9974 and 9975. Test results for the 9974 package are reported in WSRC-RP-97-00945. A series of 40-inch puncture pin tests were also performed on undamaged 9975 and 9974 packages

  9. Testing and evaluation of MHD materials and substructures

    Science.gov (United States)

    1981-06-01

    Stand that can simulate the environment in any of the various substructures of a coal fired baseline MHD power plant. After construction was completed, shakedown tests were performed, and the Test Stand was used in a series of tests to simulate the gas stream composition and temperature conditions in the baseline plant's radiant boiler. The tests were conducted in order to study the effect of stoichiometry and staged combustion on the generation of nitrogen oxide. A computer based monitoring and control system was developed that provides safe Test Stand operation, controls the critical parameters, and accurately measures, displays, and logs the necessary physical data. Several computer programs were developed to determine the thermal performance of the Test Stand, and several models were developed to predict the thermal performance of the Test Stand with bare walls and with slag coated walls, and to determine the gas stream properties as a function of temperature and pressure.

  10. 9 CFR 113.10 - Testing of bulk material for export or for further manufacture.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Testing of bulk material for export or... VECTORS STANDARD REQUIREMENTS Applicability § 113.10 Testing of bulk material for export or for further... provided in § 114.3(d) of this subchapter, samples of the bulk material shall be subjected to all required...

  11. LOCA simulation in the NRU reactor: materials test-1

    International Nuclear Information System (INIS)

    Russcher, G.E.; Marshall, R.K.; Hesson, G.M.; Wildung, N.J.; Rausch, W.N.

    1981-10-01

    A simulated loss-of-coolant accident was performed with a full-length test bundle of pressurized water reactor fuel rods. This second experiment of the program produced peak fuel cladding temperatures of 1148K (1607 0 F) and resulted in six ruptured fuel rods. Test data and initial results from the experiment are presented here in the form of photographs and graphical summaries. These results are also compared with the preceding prototypic thermal-hydraulic test results and with computer model test predictions

  12. Historical Evolution of NASA Standard Materials Testing with Hypergolic Propellants and Ammonia (NASA Standard 6001 Test 15)

    Science.gov (United States)

    Greene, Benjamin; McClure, Mark B.

    2012-01-01

    The NASA Johnson Space Center White Sands Test Facility (WSTF) has performed testing of hazardous and reactive aerospace fluids, including hypergolic propellants, with materials since the 1960s with the Apollo program. Amongst other test activities, Test 15 is a NASA standard test for evaluating the reactivity of materials with selected aerospace fluids, in particular hydrazine, monomethylhydrazine, uns-dimethylhydrazine, Aerozine 50, dinitrogen tetroxide oxidizers, and ammonia. This manuscript provides an overview of the history of Test 15 over a timeline ranging from prior to its development and first implementation as a NASA standard test in 1974 to its current refinement. Precursor documents to NASA standard tests, as they are currently known, are reviewed. A related supplementary test, international standardization, and enhancements to Test 15 are also discussed. Because WSTF was instrumental in the development and implementation of Test 15, WSTF experience and practices are referred to in this manuscript.

  13. Neutron-Irradiated Samples as Test Materials for MPEX

    International Nuclear Information System (INIS)

    Ellis, Ronald James; Rapp, Juergen

    2015-01-01

    Plasma Material Interaction (PMI) is a major concern in fusion reactor design and analysis. The Material-Plasma Exposure eXperiment (MPEX) will explore PMI under fusion reactor plasma conditions. Samples with accumulated displacements per atom (DPA) damage produced by fast neutron irradiations in the High Flux Isotope Reactor (HFIR) at Oak Ridge National Laboratory (ORNL) will be studied in the MPEX facility. This paper presents assessments of the calculated induced radioactivity and resulting radiation dose rates of a variety of potential fusion reactor plasma-facing materials (such as tungsten). The scientific code packages MCNP and SCALE were used to simulate irradiation of the samples in HFIR including the generation and depletion of nuclides in the material and the subsequent composition, activity levels, gamma radiation fields, and resultant dose rates as a function of cooling time. A challenge of the MPEX project is to minimize the radioactive inventory in the preparation of the samples and the sample dose rates for inclusion in the MPEX facility

  14. The Big Crush: An Introduction to Materials Testing

    Science.gov (United States)

    Roman, Harry T.

    2011-01-01

    Lots of engineering thinking can be involved in crushing things. As an example, engineers spend a great deal of time designing crush-proof packaging for delicate equipment and packing materials for items that must be stored or shipped. This article presents an activity wherein students can begin to appreciate the technology behind the engineering.…

  15. Ultrasonic and advanced methods for nondestructive testing and material characterization

    National Research Council Canada - National Science Library

    Chen, C. H

    2007-01-01

    ... and physics among others. There are at least two dozen NDT methods in use. In fact any sensor that can examine the inside of material nondestructively is useful for NDT. However the ultrasonic methods are still most popular because of its capability, flexibility, and relative cost effectiveness. For this reason this book places a heavy emphasis...

  16. Handbook of biomedical optics

    CERN Document Server

    Boas, David A

    2011-01-01

    Biomedical optics holds tremendous promise to deliver effective, safe, non- or minimally invasive diagnostics and targeted, customizable therapeutics. Handbook of Biomedical Optics provides an in-depth treatment of the field, including coverage of applications for biomedical research, diagnosis, and therapy. It introduces the theory and fundamentals of each subject, ensuring accessibility to a wide multidisciplinary readership. It also offers a view of the state of the art and discusses advantages and disadvantages of various techniques.Organized into six sections, this handbook: Contains intr

  17. Biomedical applications of polymers

    CERN Document Server

    Gebelein, C G

    1991-01-01

    The biomedical applications of polymers span an extremely wide spectrum of uses, including artificial organs, skin and soft tissue replacements, orthopaedic applications, dental applications, and controlled release of medications. No single, short review can possibly cover all these items in detail, and dozens of books andhundreds of reviews exist on biomedical polymers. Only a few relatively recent examples will be cited here;additional reviews are listed under most of the major topics in this book. We will consider each of the majorclassifications of biomedical polymers to some extent, inclu

  18. Powering biomedical devices

    CERN Document Server

    Romero, Edwar

    2013-01-01

    From exoskeletons to neural implants, biomedical devices are no less than life-changing. Compact and constant power sources are necessary to keep these devices running efficiently. Edwar Romero's Powering Biomedical Devices reviews the background, current technologies, and possible future developments of these power sources, examining not only the types of biomedical power sources available (macro, mini, MEMS, and nano), but also what they power (such as prostheses, insulin pumps, and muscular and neural stimulators), and how they work (covering batteries, biofluids, kinetic and ther

  19. Impact Testing for Materials Science at NASA - MSFC

    Science.gov (United States)

    Sikapizye, Mitch

    2010-01-01

    The Impact Testing Facility (ITF) at NASA - Marshall Space Flight Center is host to different types of guns used to study the effects of high velocity impacts. The testing facility has been and continues to be utilized for all NASA missions where impact testing is essential. The Facility has also performed tests for the Department of Defense, other corporations, as well as universities across the nation. Current capabilities provided by Marshall include ballistic guns, light gas guns, exploding wire gun, and the Hydrometeor Impact Gun. A new plasma gun has also been developed which would be able to propel particles at velocities of 20km/s. This report includes some of the guns used for impact testing at NASA Marshall and their capabilities.

  20. Round robin testing of thermal conductivity reference materials

    International Nuclear Information System (INIS)

    Hulstrom, L.C.; Tye, R.P.; Smith, S.E.

    1985-07-01

    The Basalt Waste Isolation Project (BWIP), operated by Rockwell Hanford Operations, has a need to determine the thermal properties of basalt in the region being considered for a nuclear waste repository in basalt. Experimental data on thermal conductivity and its variation with temperature are information required for the characterization of basalt. To establish thermal conductivity values for the reference materials, an interlaboratory measurements program was undertaken. The program was planned to meet the objectives of performing an experimental characterization of the new stock and providing a detailed analysis of the results such that reference values of thermal conductivity could be determined. This program of measurements of the thermal conductivity of Pyrex 7740 and Pyroceram 9606 has produced recommended values that are within +- 1% of those accepted previously. These measurements together with those of density indicate that the present lots of material are similar to those previously available. Pyrex 7740 and Pyroceram 9606 can continue to be used with confidence as thermal conductivity reference materials for studies on rocks and minerals and other materials of similar thermal conductivity. The uncertainty range for Pyrex 7740 and Pyroceram 9606 up to 300 0 C is +- 10.3% and +- 5.6%, respectively. This range is similar to that indicated for the previously recommended values proposed some 18 years ago. It would appear that the overall state of the art in thermal conductivity measurements for materials in this range has changed little in the intervening years. The above uncertainties, which would have been greater had not three data sets been eliminated, are greater than those which are normally claimed for each individual method. Analyses of these differences through refinements in techniques and additional measurements to higher temperatures are required. 13 refs., 7 figs., 4 tabs

  1. Biomedical applications of nanodiamond (Review)

    Science.gov (United States)

    Turcheniuk, K.; Mochalin, Vadym N.

    2017-06-01

    The interest in nanodiamond applications in biology and medicine is on the rise over recent years. This is due to the unique combination of properties that nanodiamond provides. Small size (∼5 nm), low cost, scalable production, negligible toxicity, chemical inertness of diamond core and rich chemistry of nanodiamond surface, as well as bright and robust fluorescence resistant to photobleaching are the distinct parameters that render nanodiamond superior to any other nanomaterial when it comes to biomedical applications. The most exciting recent results have been related to the use of nanodiamonds for drug delivery and diagnostics—two components of a quickly growing area of biomedical research dubbed theranostics. However, nanodiamond offers much more in addition: it can be used to produce biodegradable bone surgery devices, tissue engineering scaffolds, kill drug resistant microbes, help us to fight viruses, and deliver genetic material into cell nucleus. All these exciting opportunities require an in-depth understanding of nanodiamond. This review covers the recent progress as well as general trends in biomedical applications of nanodiamond, and underlines the importance of purification, characterization, and rational modification of this nanomaterial when designing nanodiamond based theranostic platforms.

  2. Approved reference and testing materials for use in Nuclear Waste Management Research and Development Programs

    International Nuclear Information System (INIS)

    Mellinger, G.B.; Daniel, J.L.

    1984-12-01

    This document, addressed to members of the waste management research and development community summarizes reference and testing materials available from the Nuclear Waste Materials Characterization Center (MCC). These materials are furnished under the MCC's charter to distribute reference materials essential for quantitative evaluation of nuclear waste package materials under development in the US. Reference materials with known behavior in various standard waste management related tests are needed to ensure that individual testing programs are correctly performing those tests. Approved testing materials are provided to assist the projects in assembling materials data base of defensible accuracy and precision. This is the second issue of this publication. Eight new Approved Testing Materials are listed, and Spent Fuel is included as a separate section of Standard Materials because of its increasing importance as a potential repository storage form. A summary of current characterization information is provided for each material listed. Future issues will provide updates of the characterization status of the materials presented in this issue, and information about new standard materials as they are acquired. 7 references, 1 figure, 19 tables

  3. Material test machine for tension-compression tests at high temperature

    Science.gov (United States)

    Cioletti, Olisse C.

    1988-01-01

    Apparatus providing a device for testing the properties of material specimens at high temperatures and pressures in controlled water chemistries includes, inter alia, an autoclave housing the specimen which is being tested. The specimen is connected to a pull rod which couples out of the autoclave to an external assembly which includes one or more transducers, a force balance chamber and a piston type actuator. The pull rod feeds through the force balance chamber and is compensated thereby for the pressure conditions existing within the autoclave and tending to eject the pull rod therefrom. The upper end of the push rod is connected to the actuator through elements containing a transducer comprising a linear variable differential transformer (LVDT). The housing and coil assembly of the LVDT is coupled to a tube which runs through a central bore of the pull rod into the autoclave where it is connected to one side of the specimen. The movable core of the LVDT is coupled to a stem which runs through the tube where it is then connected to the other side of the specimen through a coupling member. A transducer in the form of a load cell including one or more strain gages is located on a necked-down portion of the upper part of the pull rod intermediate the LVDT and force balance chamber.

  4. Polymer/metal nanocomposites for biomedical applications.

    Science.gov (United States)

    Zare, Yasser; Shabani, Iman

    2016-03-01

    Polymer/metal nanocomposites consisting of polymer as matrix and metal nanoparticles as nanofiller commonly show several attractive advantages such as electrical, mechanical and optical characteristics. Accordingly, many scientific and industrial communities have focused on polymer/metal nanocomposites in order to develop some new products or substitute the available materials. In the current paper, characteristics and applications of polymer/metal nanocomposites for biomedical applications are extensively explained in several categories including strong and stable materials, conductive devices, sensors and biomedical products. Moreover, some perspective utilizations are suggested for future studies. Copyright © 2015 Elsevier B.V. All rights reserved.

  5. Advanced Materials Test Methods for Improved Life Prediction of Turbine Engine Components

    National Research Council Canada - National Science Library

    Stubbs, Jack

    2000-01-01

    Phase I final report developed under SBIR contract for Topic # AF00-149, "Durability of Turbine Engine Materials/Advanced Material Test Methods for Improved Use Prediction of Turbine Engine Components...

  6. The Effect of Testing on the Retention of Coherent and Incoherent Text Material

    NARCIS (Netherlands)

    M. de Jonge (Mario); H.K. Tabbers (Huib); R.M.J.P. Rikers (Remy)

    2015-01-01

    textabstractResearch has shown that testing during learning can enhance the long-term retention of text material. In two experiments, we investigated the testing effect with a fill-in-the-blank test on the retention of text material. In Experiment 1, using a coherent text, we found no retention

  7. A report on the instrumented Charpy impact test for metallic materials

    International Nuclear Information System (INIS)

    Kozuka, Toshihiko; Yoshida, Hiroyuki.

    1988-12-01

    An instrumented testing method has been developed for Charpy impact test for steels, aluminum alloys and other materials. Using the instrumented Charpy testing machine developed, it is clearly estimated that the method is good enough to give us detailed information about the impact properties of these metallic materials. (author)

  8. The Ontology for Biomedical Investigations.

    Science.gov (United States)

    Bandrowski, Anita; Brinkman, Ryan; Brochhausen, Mathias; Brush, Matthew H; Bug, Bill; Chibucos, Marcus C; Clancy, Kevin; Courtot, Mélanie; Derom, Dirk; Dumontier, Michel; Fan, Liju; Fostel, Jennifer; Fragoso, Gilberto; Gibson, Frank; Gonzalez-Beltran, Alejandra; Haendel, Melissa A; He, Yongqun; Heiskanen, Mervi; Hernandez-Boussard, Tina; Jensen, Mark; Lin, Yu; Lister, Allyson L; Lord, Phillip; Malone, James; Manduchi, Elisabetta; McGee, Monnie; Morrison, Norman; Overton, James A; Parkinson, Helen; Peters, Bjoern; Rocca-Serra, Philippe; Ruttenberg, Alan; Sansone, Susanna-Assunta; Scheuermann, Richard H; Schober, Daniel; Smith, Barry; Soldatova, Larisa N; Stoeckert, Christian J; Taylor, Chris F; Torniai, Carlo; Turner, Jessica A; Vita, Randi; Whetzel, Patricia L; Zheng, Jie

    2016-01-01

    The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely defined meanings to describe all aspects of how investigations in the biological and medical domains are conducted. OBI re-uses ontologies that provide a representation of biomedical knowledge from the Open Biological and Biomedical Ontologies (OBO) project and adds the ability to describe how this knowledge was derived. We here describe the state of OBI and several applications that are using it, such as adding semantic expressivity to existing databases, building data entry forms, and enabling interoperability between knowledge resources. OBI covers all phases of the investigation process, such as planning, execution and reporting. It represents information and material entities that participate in these processes, as well as roles and functions. Prior to OBI, it was not possible to use a single internally consistent resource that could be applied to multiple types of experiments for these applications. OBI has made this possible by creating terms for entities involved in biological and medical investigations and by importing parts of other biomedical ontologies such as GO, Chemical Entities of Biological Interest (ChEBI) and Phenotype Attribute and Trait Ontology (PATO) without altering their meaning. OBI is being used in a wide range of projects covering genomics, multi-omics, immunology, and catalogs of services. OBI has also spawned other ontologies (Information Artifact Ontology) and methods for importing parts of ontologies (Minimum information to reference an external ontology term (MIREOT)). The OBI project is an open cross-disciplinary collaborative effort, encompassing multiple research communities from around the globe. To date, OBI has created 2366 classes and 40 relations along with textual and formal definitions. The OBI Consortium maintains a web resource (http://obi-ontology.org) providing details on the people, policies, and issues being addressed

  9. The Ontology for Biomedical Investigations.

    Directory of Open Access Journals (Sweden)

    Anita Bandrowski

    Full Text Available The Ontology for Biomedical Investigations (OBI is an ontology that provides terms with precisely defined meanings to describe all aspects of how investigations in the biological and medical domains are conducted. OBI re-uses ontologies that provide a representation of biomedical knowledge from the Open Biological and Biomedical Ontologies (OBO project and adds the ability to describe how this knowledge was derived. We here describe the state of OBI and several applications that are using it, such as adding semantic expressivity to existing databases, building data entry forms, and enabling interoperability between knowledge resources. OBI covers all phases of the investigation process, such as planning, execution and reporting. It represents information and material entities that participate in these processes, as well as roles and functions. Prior to OBI, it was not possible to use a single internally consistent resource that could be applied to multiple types of experiments for these applications. OBI has made this possible by creating terms for entities involved in biological and medical investigations and by importing parts of other biomedical ontologies such as GO, Chemical Entities of Biological Interest (ChEBI and Phenotype Attribute and Trait Ontology (PATO without altering their meaning. OBI is being used in a wide range of projects covering genomics, multi-omics, immunology, and catalogs of services. OBI has also spawned other ontologies (Information Artifact Ontology and methods for importing parts of ontologies (Minimum information to reference an external ontology term (MIREOT. The OBI project is an open cross-disciplinary collaborative effort, encompassing multiple research communities from around the globe. To date, OBI has created 2366 classes and 40 relations along with textual and formal definitions. The OBI Consortium maintains a web resource (http://obi-ontology.org providing details on the people, policies, and issues being

  10. Practical Considerations of Design, Fabrication and Tests for Composite Materials,

    Science.gov (United States)

    1982-09-01

    that c < o (1 - 2a/w) as in Fig 6. IMPACT DAMAGE IN COMPOSITES Traditionally pendulum impact tests such as Izod and Charpy tests have been used to...more concern with the residual mechanical properties under realistic loading than with the energy absorption measured by conventional pendulum impact...cracks longer than about 20 mm in torsion pendulum experiments at about 5% of the failure strain, and they show that this is about the same level of

  11. The SCC testing of nuclear steam generator tubing materials

    Science.gov (United States)

    Doherty, P. E.; Sarver, J. M.; Miglin, B. P.

    1996-05-01

    The integrity of heat-exchanger tubes in a nuclear reaction system is crucial for the safe operation of a power plant. In order to study the corrosion behavior of certain alloys, constant extension rate (CERT) tests were performed on alloy 690 and alloy 800 nuclear steam generator tubing specimens. In this article, the CERT test results (such as maximum stress achieved and crack morphology) are correlated to tubing microstructure, chemistry, and manufacturing processes.

  12. Applicability of Aerospace Materials Ground Flammability Test Data to Spacecraft Environments Theory and Applied Technologies

    Science.gov (United States)

    Hirsch, David; Williams, Jim; Beeson, Harold

    2009-01-01

    This slide presentation reviews the use of ground test data in reference to flammability to spacecraft environments. It reviews the current approach to spacecraft fire safety, the challenges to fire safety that the Constellation program poses, the current trends in the evaluation of the Constellation materials flammability, and the correlation of test data from ground flammability tests with the spacecraft environment. Included is a proposal for testing and the design of experiments to test the flammability of materials under similar spacecraft conditions.

  13. Biomedical Engineering Laboratory

    National Research Council Canada - National Science Library

    Bodruzzama, Mohammad

    2003-01-01

    ... and on-line analysis of the biomedical signals. Each Biopac system-based laboratory station consists of real-time data acquisition system, amplifiers for EMG, EKG, EEG, and equipment for the study of Plethysmography, evoked response, cardio...

  14. Exploring subdomain variation in biomedical language

    Directory of Open Access Journals (Sweden)

    Séaghdha Diarmuid Ó

    2011-05-01

    Full Text Available Abstract Background Applications of Natural Language Processing (NLP technology to biomedical texts have generated significant interest in recent years. In this paper we identify and investigate the phenomenon of linguistic subdomain variation within the biomedical domain, i.e., the extent to which different subject areas of biomedicine are characterised by different linguistic behaviour. While variation at a coarser domain level such as between newswire and biomedical text is well-studied and known to affect the portability of NLP systems, we are the first to conduct an extensive investigation into more fine-grained levels of variation. Results Using the large OpenPMC text corpus, which spans the many subdomains of biomedicine, we investigate variation across a number of lexical, syntactic, semantic and discourse-related dimensions. These dimensions are chosen for their relevance to the performance of NLP systems. We use clustering techniques to analyse commonalities and distinctions among the subdomains. Conclusions We find that while patterns of inter-subdomain variation differ somewhat from one feature set to another, robust clusters can be identified that correspond to intuitive distinctions such as that between clinical and laboratory subjects. In particular, subdomains relating to genetics and molecular biology, which are the most common sources of material for training and evaluating biomedical NLP tools, are not representative of all biomedical subdomains. We conclude that an awareness of subdomain variation is important when considering the practical use of language processing applications by biomedical researchers.

  15. Biomedical signal analysis

    CERN Document Server

    Rangayyan, Rangaraj M

    2015-01-01

    The book will help assist a reader in the development of techniques for analysis of biomedical signals and computer aided diagnoses with a pedagogical examination of basic and advanced topics accompanied by over 350 figures and illustrations. Wide range of filtering techniques presented to address various applications. 800 mathematical expressions and equations. Practical questions, problems and laboratory exercises. Includes fractals and chaos theory with biomedical applications.

  16. Biomedical signal processing

    CERN Document Server

    Akay, Metin

    1994-01-01

    Sophisticated techniques for signal processing are now available to the biomedical specialist! Written in an easy-to-read, straightforward style, Biomedical Signal Processing presents techniques to eliminate background noise, enhance signal detection, and analyze computer data, making results easy to comprehend and apply. In addition to examining techniques for electrical signal analysis, filtering, and transforms, the author supplies an extensive appendix with several computer programs that demonstrate techniques presented in the text.

  17. Nondestructive detection of local material thinning in ferromagnetic materials by Magnetic Adaptive Testing

    Czech Academy of Sciences Publication Activity Database

    Vértesy, G.; Uchimoto, T.; Takagi, S.; Takagi, T.; Tomáš, Ivan

    2013-01-01

    Roč. 5, č. 1 (2013), 7-14 ISSN 1883-9894 Institutional support: RVO:68378271 Keywords : wall thinning * magnetic nondestructive testing * Magnetic Adaptive Testing * magnetic hysteresis Subject RIV: BM - Solid Matter Physics ; Magnetism

  18. Experimental patch testing with chromium-coated materials.

    Science.gov (United States)

    Bregnbak, David; Thyssen, Jacob P; Jellesen, Morten S; Zachariae, Claus; Johansen, Jeanne D

    2017-06-01

    Chromium coatings on metal alloys can be decorative, and prevent corrosion and metal ion release. We recently showed that handling of a chromium-containing disc resulted in chromium deposition on the skin. To examine patch test reactivity to chromium-coated discs. We included 15 patients: 10 chromium-allergic patients, and 5 patients without chromium allergy. All were patch tested with potassium dichromate, cobalt chloride, nickel sulfate, and nine different metallic discs. The chromium-allergic patients were also patch tested with serial dilutions of potassium dichromate. Positive/weaker reactions were observed to disc B (1 of 10), disc C (1 of 10), and disc D, disc E, and disc I (4 of 10 each). As no controls reacted to any of the discs, the weak reactions indicate allergic reactions. Positive patch test reactions to 1770 ppm chromium(VI) in the serial dilutions of potassium dichromate were observed in 7 of 10 patients. When the case group was narrowed down to include only the patients with a current positive patch test reaction to potassium dichromate, elicitation of dermatitis by both chromium(III) and chromium(VI) discs was observed in 4 of 7 of patients. Many of the patients reacted to both chromium(III) and chromium(VI) surfaces. Our results indicate that both chromium(VI) and chromium(III) pose a risk to chromium-allergic patients. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  19. R20 Programme: Field testing of grouting materials

    International Nuclear Information System (INIS)

    Ranta-Korpi, R.; Karttunen, P.; Sievaenen, U.

    2008-02-01

    In the year 2004 Finnish nuclear waste management organisation Posiva Oy started to construct an underground rock characterisation facility in Olkiluoto, Eurajoki, Western Finland. The ONKALO was planned to be a final disposal of spent nuclear fuel in Finland. This facility is going to be finished in the end of the year 2010. In ONKALO it is important to grout the water conductive structures to minimize the leakage of the inflowing groundwater in order to keep the geohydrogical environment unchanged and the repository conditions safe. Before the construction began the development of the grouts suitable for this demanding environment was started. Especially pH, the penetration ability and rheology have been the matter of interest. One target for the grout has been that the pH is relatively low. These grouts have different properties than the normal grouts. Several laboratory and field tests have been done for low pH grouts. The suitable recipies are studied in laboratory and the properties are verified in field. This work concerns the field testing of several low pH grout recipies. The different W/DM -ratios and SPL contents were studied. Besides the customary test methods, two new measurement methods were taken into use: the sand column test for measuring the penetration ability and the stick test for determining the plastic viscosity and yield value. The relationships between different properties, the properties as a function of the time and the effect of the (orig.)

  20. Luminescent nanodiamonds for biomedical applications.

    Science.gov (United States)

    Say, Jana M; van Vreden, Caryn; Reilly, David J; Brown, Louise J; Rabeau, James R; King, Nicholas J C

    2011-12-01

    In recent years, nanodiamonds have emerged from primarily an industrial and mechanical applications base, to potentially underpinning sophisticated new technologies in biomedical and quantum science. Nanodiamonds are relatively inexpensive, biocompatible, easy to surface functionalise and optically stable. This combination of physical properties are ideally suited to biological applications, including intracellular labelling and tracking, extracellular drug delivery and adsorptive detection of bioactive molecules. Here we describe some of the methods and challenges for processing nanodiamond materials, detection schemes and some of the leading applications currently under investigation.

  1. Assembly and testing of microparticle and microcapsule smart tattoo materials

    Science.gov (United States)

    McShane, Michael J.

    2007-01-01

    Microscale biochemical sensors are attractive for in vitro diagnostics and disease management, as well as medical and biological research applications. Fluorescent sensors, coupling specific glucose-binding proteins with fluorescent readout methods, have been developed for this purpose. Our work has focused on the development of assembly and packaging systems for producing micro- and nanoscale sensing components that can be used as implants, intracellular reporters, or as elements in larger systems. Both hybrid organic/inorganic particles and hollow microshells have been developed to physically couple the sensing materials together in biocompatible, semipermeable packages. Fabrication details and sensor characterization are used to demonstrate the potential of these sensor concepts.

  2. Impact test on natural fiber reinforced polymer composite materials

    Directory of Open Access Journals (Sweden)

    D. Chandramohan

    2013-06-01

    Full Text Available In this research, natural fibers like Sisal (Agave sisalana, Banana (Musa sepientum & Roselle (Hibiscus sabdariffa , Sisal and banana (hybrid , Roselle and banana (hybrid and Roselle and sisal (hybrid are fabricated with bio epoxy resin using molding method. In this work, impact strength of Sisal and banana (hybrid, Roselle and banana (hybridand Roselle and sisal (hybrid composite at dry and wet conditions were studied. Impact test were conducted izod impact testing machine. In this work micro structure of the specimens are scanned by the Scanning Electron Microscope.

  3. A reproducible oral microcosm biofilm model for testing dental materials.

    Science.gov (United States)

    Rudney, J D; Chen, R; Lenton, P; Li, J; Li, Y; Jones, R S; Reilly, C; Fok, A S; Aparicio, C

    2012-12-01

    Most studies of biofilm effects on dental materials use single-species biofilms, or consortia. Microcosm biofilms grown directly from saliva or plaque are much more diverse, but difficult to characterize. We used the Human Oral Microbial Identification Microarray (HOMIM) to validate a reproducible oral microcosm model. Saliva and dental plaque were collected from adults and children. Hydroxyapatite and dental composite discs were inoculated with either saliva or plaque, and microcosm biofilms were grown in a CDC biofilm reactor. In later experiments, the reactor was pulsed with sucrose. DNA from inoculums and microcosms was analysed by HOMIM for 272 species. Microcosms included about 60% of species from the original inoculum. Biofilms grown on hydroxyapatite and composites were extremely similar. Sucrose pulsing decreased diversity and pH, but increased the abundance of Streptococcus and Veillonella. Biofilms from the same donor, grown at different times, clustered together. This model produced reproducible microcosm biofilms that were representative of the oral microbiota. Sucrose induced changes associated with dental caries. This is the first use of HOMIM to validate an oral microcosm model that can be used to study the effects of complex biofilms on dental materials. © 2012 The Society for Applied Microbiology.

  4. Advanced In-pile Instrumentation for Material and Test Reactors

    International Nuclear Information System (INIS)

    Rempe, J.L.; Knudson, D.L.; Daw, J.E.; Unruh, T.C.; Chase, B.M.; Davis, K.L.; Palmer, A.J.; Schley, R.S.

    2013-06-01

    The US Department of Energy sponsors the Advanced Test Reactor (ATR) National Scientific User Facility (NSUF) program to promote U.S. research in nuclear science and technology. By attracting new research users - universities, laboratories, and industry - the ATR NSUF facilitates basic and applied nuclear research and development, advancing U.S. energy security needs. A key component of the ATR NSUF effort is to design, develop, and deploy new in-pile instrumentation techniques that are capable of providing real-time measurements of key parameters during irradiation. This paper describes the strategy developed by the Idaho National Laboratory (INL) for identifying instrumentation needed for ATR irradiation tests and the program initiated to obtain these sensors. New sensors developed from this effort are identified; and the progress of other development efforts is summarized. As reported in this paper, INL staff is currently involved in several tasks to deploy real-time length and flux detection sensors, and efforts have been initiated to develop a crack growth test rig. Tasks evaluating 'advanced' technologies, such as fiber-optics based length detection and ultrasonic thermometers are also underway. In addition, specialized sensors for real-time detection of temperature and thermal conductivity are not only being provided to NSUF reactors, but are also being provided to several international test reactors. (authors)

  5. Experimental patch testing with chromium-coated materials

    DEFF Research Database (Denmark)

    Bregnbak, David; Thyssen, Jacob P; Jellesen, Morten Stendahl

    2017-01-01

    Chromium coatings on metal alloys can be decorative, and prevent corrosion and metal ion release. We recently showed that handling of a chromium-containing disc resulted in chromium deposition on the skin. To examine patch test reactivity to chromium-coated discs. We included 15 patients: 10...

  6. Testing of Confining Pressure Impacton Explosion Energy of Explosive Materials

    Science.gov (United States)

    Drzewiecki, Jan; Myszkowski, Jacek; Pytlik, Andrzej; Pytlik, Mateusz

    2017-06-01

    This paper presents the results of testing the explosion effects of two explosive charges placed in an environment with specified values of confining pressure. The aim of this study is to determine the impact of variable environmental conditions on the suitability of particular explosives for their use in the prevention of natural hazards in hard coal mining. The research results will contribute to improving the efficiency of currently adopted technologies of natural hazard prevention and aid in raising the level of occupational safety. To carry out the subject matter measurements, a special test stand was constructed which allows the value of the initial pressure inside the chamber, which constitutes its integral part, to be altered before the detonation of the charge being tested. The obtained characteristics of the pressure changes during the explosion of the analysed charge helped to identify the work (energy) which was produced during the process. The test results are a valuable source of information, opening up new possibilities for the use of explosives, the development of innovative solutions for the construction of explosive charges and their initiation.

  7. Consensus stability testing protocols for organic photovoltaic materials and devices

    DEFF Research Database (Denmark)

    Reese, Matthew O.; Gevorgyan, Suren; Jørgensen, Mikkel

    2011-01-01

    Procedures for testing organic solar cell devices and modules with respect to stability and operational lifetime are described. The descriptions represent a consensus of the discussion and conclusions reached during the first 3 years of the international summit on OPV stability (ISOS). The proced...

  8. Application of Denisyuk pulsed holography to material testing

    NARCIS (Netherlands)

    Renesse, R.L. van; Burgmeijer, J.W.

    1983-01-01

    When holography is applied outside the laboratory, some well known problems are experienced: vibrations, rigid body motion, stray daylight. Pulse holography can overcome the difficulties with vibrations, but the other problems are less easily solved. When the object area to be holographically tested

  9. Use of a radionuclid to label material for radioactive tests

    International Nuclear Information System (INIS)

    Saklad, E.L.; Layne, W.W.

    1977-01-01

    In order to increase the stability of a test substance labelled with a radiotracer 99 Tcsup(m) the serum albumin portion of human serum albumin, of stannous macroaggregate-forming albumin and of the albumin-bloodpool are defatted. This is achieved by charcoal treatment or the acid precipitation method. (DG) [de

  10. Statistical approach for collaborative tests, reference material certification procedures

    International Nuclear Information System (INIS)

    Fangmeyer, H.; Haemers, L.; Larisse, J.

    1977-01-01

    The first part introduces the different aspects in organizing and executing intercomparison tests of chemical or physical quantities. It follows a description of a statistical procedure to handle the data collected in a circular analysis. Finally, an example demonstrates how the tool can be applied and which conclusion can be drawn of the results obtained

  11. Irradiation test of diagnostic components for ITER application in a fission reactor, Japan Materials Testing Reactor

    International Nuclear Information System (INIS)

    Shikama, T.; Nishitani, T.; Kakuta, T.

    2003-01-01

    Radiation effects on components and materials will be one of the most serious technological issues in fusion systems realizing burning plasmas. Especially, diagnostic components, which should play crucial roles to control plasmas and to understand physics of burning plasmas, will be exposed to high-flux neutrons and gamma-rays. Dynamics radiation effects will affects performance of components substantially from beginning of exposure to radiation environments, and accumulated radiation effects will gradually degrade their functioning abilities in the course of their services. High-power-density fission reactors will be only realistic tools to simulate the irradiation environments expected in burning-plasma fusion machines such as the ITER, at present. Some key diagnostic components, namely magnetic coils, bolometers, and optical fibers, were irradiation-tested in a fission reactor, JMTR, to evaluate their performances under heavy irradiation environments. Results indicate that the ITER-relevant diagnostic components could be developed in time, though there are still some technological problems to overcome. (author)

  12. Thermal Response of UHMWPE Materials in a Flash Flame Test Environment

    Science.gov (United States)

    2014-11-13

    COVERED (From - To) October 2012 – April 2014 4. TITLE AND SUBTITLE THERMAL RESPONSE OF UHMWPE MATERIALS IN A FLASH FLAME TEST ENVIRONMENT 5a. CONTRACT ...an FR fabric outer layer of Tencate Defender M. Prior to fabricating test garments , preliminary flash flame testing was conducted with a midscale...test setup, which guided the full-scale thermal manikin test plan. Test garments were fabricated for evaluation on the instrumented thermal test

  13. Questions of qualification exam for non-destructive testing and materials science - the first level

    International Nuclear Information System (INIS)

    Shaaban, H.I.; Addarwish, J.M.A.

    2013-01-01

    The book contains seven chapters: Questions of qualification for magnetic particles testing method - Questions of qualification for liquids penetrant testing method - Questions of qualification for the visual inspection testing method - Questions of qualification for the ultrasonic testing method - Questions of qualification for the eddy current testing method - Questions of rehabilitation for industrial radiographic testing method - Qualification questions about materials science and manufacturing defects of castings and welding and comparison between non-destructive testing methods.

  14. Practical and theoretical considerations on the fracture toughness testing of dental restorative materials.

    Science.gov (United States)

    Belli, Renan; Wendler, Michael; Zorzin, José I; Lohbauer, Ulrich

    2018-01-01

    An important tool in materials research, development and characterization regarding mechanical performance is the testing of fracture toughness. A high level of accuracy in executing this sort of test is necessary, with strict requirements given in extensive testing standard documents. Proficiency in quality specimen fabrication and test requires practice and a solid theoretical background, oftentimes overlooked in the dental community. In this review we go through some fundamentals of the fracture mechanics concepts that are relevant to the understanding of fracture toughness testing, and draw attention to critical aspects of practical nature that must be fulfilled for validity and accuracy in results. We describe our experience with some testing methodologies for CAD/CAM materials and discuss advantages and shortcomings of different tests in terms of errors in testing the applicability of the concept of fracture toughness as a single-value material-specific property. Copyright © 2017 The Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  15. Sex roles in instructional materials: testing the stereotypes.

    Science.gov (United States)

    Zimmerman, M L; Casanova, M E; Stern, D P; Auman, S S

    1982-01-01

    This special report discusses the significance and potential benefit of portraying men in nontraditional sex roles within pictorial instructional print materials on health and child care. It is based on the cognitive and behavioral findings of a comparative research study conducted in selected rural and periurban areas of Mexico on the use of two versions of an ORS pictorial pamphlet. Major findings of the study were: (1) portraying nontraditional sex roles for men in the ORS pamphlet did not reduce the credibility of technical information contained in the pamphlet; (2) a significantly greater number of subjects preferred the version that portrayed the father figure as co-caretaker of a sick child. These unexpected results have important implications for instructional and motivational communication and health education projects throughout the developing world.

  16. Environmental test program for superconducting materials and devices

    Science.gov (United States)

    Haertling, Gene; Randolph, Henry; Hsi, Chi-Shiung; Verbelyi, Darren

    1991-01-01

    This report is divided into two parts. The first dealing with work involved with Clemson University and the second with the results from Westinghouse/Savannah River. Both areas of work involved low noise, low thermal conductivity superconducting grounding links used in the NASA-sponsored Spectroscopy of the Atmosphere using Far Infrared Emission (SAFIRE) Project. Clemson prepared the links from YBa2Cu3O(7-x) superconductor tape that was mounted on a printed circuit board and encapsulated with epoxy resin. The Clemson program includes temperature vs. resistance, liquid nitrogen immersion, water immersion, thermal cycling, humidity, and radiation testing. The evaluation of the links under a long term environmental test program is described. The Savannah River program includes gamma irradiation, vibration, and long-term evaluation. The progress made in these evaluations is discussed.

  17. System Management on Accreditation Test for Radioactive Material

    International Nuclear Information System (INIS)

    Sohn, S. C.; Kim, Y. B.; Kim, H.W.

    2009-01-01

    The nuclear analytical service was conducted for the determination of nuclear speciation, isotope ratio, elemental analysis, and nuclear analysis in about 184 samples. Their results were recorded as an accreditation report. In this research, the quality control through the verification of uncertainty and confidence was carried out by participation in mutual cross-comparison test administrated by international accreditation organization. The quality control for the analytical counting devices was also conducted using the standard references

  18. Hybrid microcircuit technology handbook materials, processes, design, testing and production

    CERN Document Server

    Licari, James J

    1998-01-01

    The Hybrid Microcircuit Technology Handbook integrates the many diverse technologies used in the design, fabrication, assembly, and testing of hybrid segments crucial to the success of producing reliable circuits in high yields. Among these are: resistor trimming, wire bonding, die attachment, cleaning, hermetic sealing, and moisture analysis. In addition to thin films, thick films, and assembly processes, important chapters on substrate selections, handling (including electrostatic discharge), failure analysis, and documentation are included. A comprehensive chapter of design guidelines will

  19. Errors Associated with Flexure Testing of Brittle Materials

    Science.gov (United States)

    1987-07-01

    Computer Analysis Worksheet. .. .... ................ . ........42 NOMENCLATURE E Young’s modulus of the test vmaterial E c Young’s modulus in compression of...lolden-Day Scrie in Mathenatical Physics. J. L. Brandstatter, ed.. 1963. p. 204. 4 is also an area in whigh further analysis will be required to assess...was used to compute the percent error because it would yield the largest error. Although the analysis was applied to a three-point loaded beam, the

  20. Standard test method for ranking resistance of materials to sliding wear using block-on-ring wear test

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2005-01-01

    1.1 This test method covers laboratory procedures for determining the resistance of materials to sliding wear. The test utilizes a block-on-ring friction and wear testing machine to rank pairs of materials according to their sliding wear characteristics under various conditions. 1.2 An important attribute of this test is that it is very flexible. Any material that can be fabricated into, or applied to, blocks and rings can be tested. Thus, the potential materials combinations are endless. However, the interlaboratory testing has been limited to metals. In addition, the test can be run with various lubricants, liquids, or gaseous atmospheres, as desired, to simulate service conditions. Rotational speed and load can also be varied to better correspond to service requirements. 1.3 The values stated in SI units are to be regarded as the standard. The values given in parentheses are for information only. Wear test results are reported as the volume loss in cubic millimetres for both the block and ring. Materials...

  1. Testing of reactor fuel materials using nuclear techniques

    International Nuclear Information System (INIS)

    Khouri, M.T.F.C.

    1978-01-01

    The tests presented here apply to: the quantitative determination of uranium in the core of fuel element plates by the detection of the number of neutrons produced in photo induced reactions in uranium; the determination of 235 U proportion in uranium dioxide samples, in the form of uranyl nitrate, by the technique of the detection of tracks produced by fission fragments and in pellet samples by passive gamma spectrometry and the checking of uranium homogenization distribution in fuel plates and uranium dioxide pellets. (Author) [pt

  2. Standard Test Method for Dimensional Stability of Sandwich Core Materials

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2002-01-01

    1.1 This test method covers the determination of the sandwich core dimensional stability in the two plan dimensions. 1.2 The values stated in SI units are to be regarded as the standard. The inch-pound units given may be approximate. This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

  3. Thermal Analysis and Testing of Candidate Materials for PAIDAE Inflatable Aeroshell

    Science.gov (United States)

    DelCorso, Joseph A.; Bruce, Walter E., III; Liles, Kaitlin A.; Hughes, Stephen J.

    2009-01-01

    The Program to Advance Inflatable-Decelerators for Atmospheric Entry (PAIDAE) is a NASA project tasked with developing and evaluating viable inflatable-decelerator aeroshell geometries and materials. Thermal analysis of material layups supporting an inflatable aeroshell was completed in order to identify expected material response, failure times, and to establish an experimental test matrix to keep barrier layer materials from reaching critical temperature limits during thermal soak. Material layups were then tested in the 8- foot High Temperature Tunnel (8'HTT), where they were subjected to hypersonic aerothermal heating conditions, similar to those expected for a Mars entry. This paper presents a broad overview of the thermal analysis supporting multiple materials, and layup configurations tested in the 8'HTT at flight conditions similar to those that would be experienced during Mars entry trajectories. Direct comparison of TPS samples tested in the 8'HTT verify that the thermal model accurately predicted temperature profiles when there are up to four materials in the test layup. As the number of material layers in each test layup increase (greater than 4), the accuracy of the prediction decreases significantly. The inaccuracy of the model predictions for layups with more than four material layers is believed to be a result of the contact resistance values used throughout the model being inaccurate. In addition, the harsh environment of the 8'HTT, including hot gas penetrating through the material layers, could also be a contributing factor.

  4. Compression of pulsed electron beams for material tests

    Science.gov (United States)

    Metel, Alexander S.

    2018-03-01

    In order to strengthen the surface of machine parts and investigate behavior of their materials exposed to highly dense energy fluxes an electron gun has been developed, which produces the pulsed beams of electrons with the energy up to 300 keV and the current up to 250 A at the pulse width of 100-200 µs. Electrons are extracted into the accelerating gap from the hollow cathode glow discharge plasma through a flat or a spherical grid. The flat grid produces 16-cm-diameter beams with the density of transported per one pulse energy not exceeding 15 J·cm-2, which is not enough even for the surface hardening. The spherical grid enables compression of the beams and regulation of the energy density from 15 J·cm-2 up to 15 kJ·cm-2, thus allowing hardening, pulsed melting of the machine part surface with the further high-speed recrystallization as well as an explosive ablation of the surface layer.

  5. Initial ACTR retrieval technology evaluation test material recommendations

    International Nuclear Information System (INIS)

    Powell, M.R.

    1996-04-01

    Millions of gallons of radiaoctive waste are contained in underground storage tanks at Hanford (SE Washington). Techniques for retrieving much of this waste from the storage tanks have been developed. Current baseline approach is to use sluice jets for single-shell tanks and mixer pumps for double-shell tanks. The Acquire Commercial Technology for Retrieval (ACTR) effort was initiated to identify potential improvements in or alternatives to the baseline waste retrieval methods. Communications with a variety of vendors are underway to identify improved methods that can be implemented at Hanford with little or no additional development. Commercially available retrieval methods will be evaluated by a combination of testing and system-level cost estimation. Current progress toward developing waste simulants for testing ACTR candidate methods is reported; the simulants are designed to model 4 different types of tank waste. Simulant recipes are given for wet sludge, hardpan/dried sludge,hard saltcake, and soft saltcake. Comparisons of the waste and simulant properties are documented in this report

  6. Impact Testing of Aluminum 2024 and Titanium 6Al-4V for Material Model Development

    Science.gov (United States)

    Pereira, J. Michael; Revilock, Duane M.; Lerch, Bradley A.; Ruggeri, Charles R.

    2013-01-01

    One of the difficulties with developing and verifying accurate impact models is that parameters such as high strain rate material properties, failure modes, static properties, and impact test measurements are often obtained from a variety of different sources using different materials, with little control over consistency among the different sources. In addition there is often a lack of quantitative measurements in impact tests to which the models can be compared. To alleviate some of these problems, a project is underway to develop a consistent set of material property, impact test data and failure analysis for a variety of aircraft materials that can be used to develop improved impact failure and deformation models. This project is jointly funded by the NASA Glenn Research Center and the FAA William J. Hughes Technical Center. Unique features of this set of data are that all material property data and impact test data are obtained using identical material, the test methods and procedures are extensively documented and all of the raw data is available. Four parallel efforts are currently underway: Measurement of material deformation and failure response over a wide range of strain rates and temperatures and failure analysis of material property specimens and impact test articles conducted by The Ohio State University; development of improved numerical modeling techniques for deformation and failure conducted by The George Washington University; impact testing of flat panels and substructures conducted by NASA Glenn Research Center. This report describes impact testing which has been done on aluminum (Al) 2024 and titanium (Ti) 6Al-4vanadium (V) sheet and plate samples of different thicknesses and with different types of projectiles, one a regular cylinder and one with a more complex geometry incorporating features representative of a jet engine fan blade. Data from this testing will be used in validating material models developed under this program. The material

  7. Electrostatic discharge attenuation test for the characterization of ESD protective materials

    Energy Technology Data Exchange (ETDEWEB)

    Paasi, Jaakko [VTT Technical Research Centre of Finland, PO Box 1300, FI-33101 Tampere (Finland); Viheriaekoski, Toni; Sutela, Lassi [Nokia Corporation, PO Box 370, FI-00045 Nokia Group, Espoo (Finland); Tamminen, Pasi K [Nokia Corporation, Visiokatu 3, FI-33721 Tampere (Finland)], E-mail: jaakko.paasi@vtt.fi

    2008-12-01

    New experimental method has been developed to evaluate materials, tools, equipment and packaging used in the electronics production environment under Charged Device Model (CDM) type of electrostatic discharge (ESD) transients. The method is intended to characterize the ability of the material or object to attenuate ESD energy and peak discharge current when a charged device is discharged into the material under test. The test is supplementary for the standard quasi-static measurements of ESD control programs in the cases where standard measurements do not give sufficient information due to voltage non-linearity, complexity or shape of the material or object under test.

  8. Electrostatic discharge attenuation test for the characterization of ESD protective materials

    International Nuclear Information System (INIS)

    Paasi, Jaakko; Viheriaekoski, Toni; Sutela, Lassi; Tamminen, Pasi K

    2008-01-01

    New experimental method has been developed to evaluate materials, tools, equipment and packaging used in the electronics production environment under Charged Device Model (CDM) type of electrostatic discharge (ESD) transients. The method is intended to characterize the ability of the material or object to attenuate ESD energy and peak discharge current when a charged device is discharged into the material under test. The test is supplementary for the standard quasi-static measurements of ESD control programs in the cases where standard measurements do not give sufficient information due to voltage non-linearity, complexity or shape of the material or object under test.

  9. Corrosion test on candidate waste package basket materials for the Yucca Mountain project

    International Nuclear Information System (INIS)

    Van Konynenburg, R.A.; Curtis, P.G.

    1996-01-01

    A scoping corrosion test was performed on candidate waste package basket materials in order to assist in selecting materials for package design and to help in designing longer-term corrosion tests. The corrosion solution was buffered near pH4, was in contact with air, and contained chemical species expected to be produced by radiolysis. The test was conducted at 90 C for 96 hours. Samples included aluminum-, copper-, stainless steel-, and zirconium-based metallic materials and several ceramics, incorporating neutron absorber elements. Sample weight losses and solution chemical changes were measured. Both corrosion of the host materials and dissolution of the neutron absorber elements were studied

  10. Cryogenic Thermal Performance Testing of Bulk-Fill and Aerogel Insulation Materials

    Science.gov (United States)

    Scholtens, B. E.; Fesmire, J. E.; Sass, J. P.; Augustynowicz, S. D.; Heckle, K. W.

    2007-01-01

    The research testing and demonstration of new bulk-fill materials for cryogenic thermal insulation systems was performed by the Cryogenics Test Laboratory at NASA Kennedy Space Center. Thermal conductivity testing under actual-use cryogenic conditions is a key to understanding the total system performance encompassing engineering, economics, and materials factors. A number of bulk fill insulation materials, including aerogel beads, glass bubbles, and perlite powder, were tested using a new cylindrical cryostat. Boundary temperatures for the liquid nitrogen boil-off method were 293 K and 78 K. Tests were performed as a function of cold vacuum pressure from high vacuum to no vacuum conditions. Results are compared with other complementary test methods in the range of 300 K to 20 K. Various testing techniques are shown to be required to obtain a complete understanding of the operating performance of a material and to provide data for answers to design engineering questions.

  11. Silica control and materials tests at the Salton Sea geothermal field

    Energy Technology Data Exchange (ETDEWEB)

    Quong, R.; Harrar, J.E.; McCright, R.D.; Locke, R.D.; Lorensen, L.E.; Tardiff, G.E.

    1979-06-07

    The Lawrence Livermore Laboratory maintains and operates a test facility near Niland, California, in the Imperial Valley for field studies on SSGF brine chemistry, scale and solids control, materials, and injection. Recent work in silica control and materials testing is reviewed.

  12. The Status of the Testing Effect for Complex Materials: Still a Winner

    Science.gov (United States)

    Rawson, Katherine A.

    2015-01-01

    The target articles in the special issue address a timely and important question concerning whether practice tests enhance learning of complex materials. The consensus conclusion from these articles is that the testing effect does not obtain for complex materials. In this commentary, I discuss why this conclusion is not warranted either by the…

  13. Test methodology for elemental sulfur resistant advanced materials for oil and gas field equipment

    Energy Technology Data Exchange (ETDEWEB)

    Steinbeck, G. [Verein Deutscher Eisenhuettenleute, Duesseldorf (Germany); Bruckhoff, W. [BEB Erdgas und Erdoel GmbH, Hannover (Germany); Koehler, M. [Krupp-VDM AG, Werdohl (Germany); Schlerkmann, H. [Mannesmann Forschungsinstitut, Duisburg (Germany); Schmitt, G. [Iserlohn Polytechnic (Germany). Lab. for Corrosion Protection

    1995-10-01

    The great variety of methodologies for testing the performance of advanced materials for resistance to elemental sulfur in oil and gas industry prompted the Technical Committee for Corrosion of the German Iron and Steel Institute (VDEh) to define recommended test procedures. These procedures have already found wide acceptance in the German materials and oil and gas industry.

  14. Test facilities for radioactive materials transport packages (Transportation Technology Center Inc., Pueblo, Colorado, USA)

    International Nuclear Information System (INIS)

    Conlon, P.C.L.

    2001-01-01

    Transportation Technology Center, Inc. is capable of conducting tests on rail vehicle systems designed for transporting radioactive materials including low level waste debris, transuranic waste, and spent nuclear fuel and high level waste. Services include rail vehicle dynamics modelling, on-track performance testing, full scale structural fatigue testing, rail vehicle impact tests, engineering design and technology consulting, and emergency response training. (author)

  15. Dredged Material Evaluations: Review of Zooplankton Toxicity Test Methods for Marine Water Quality Evaluations

    Science.gov (United States)

    2016-09-01

    reduce interactive effects between food and contaminants of concern. PUBLISHED RESEARCH USING ALTERNATIVE ZOOPLANKTON: While a few standard test...accumulation of contaminants of concern into biological tissue (bioaccumulation tests) after sediment settles at the placement site. Technical...EMBRYOS: The American Society for Testing and Materials International (ASTM) has produced standardized toxicity tests for echinoderm (ASTM E1563-98

  16. Engine cyclic durability by analysis and material testing

    Science.gov (United States)

    Kaufman, A.; Halford, G. R.

    1984-01-01

    The problem of calculating turbine engine component durability is addressed. Nonlinear, finite-element structural analyses, cyclic constitutive behavior models, and an advanced creep-fatigue life prediction method called strainrange partitioning were assessed for their applicability to the solution of durability problems in hot-section components of gas turbine engines. Three different component or subcomponent geometries are examined: a stress concentration in a turbine disk; a louver lip of a half-scale combustor linear; and a squealer tip of a first-stage high-pressure turbine blade. Cyclic structural analyses were performed for all three problems. The computed strain-temperature histories at the critical locations of the combustor linear and turbine blade components were imposed on smooth specimens in uniaxial, strain-controlled, thermomechanical fatigue tests of evaluate the structural and life analysis methods.

  17. Tensile tests of niobium material for SRF cavities

    Energy Technology Data Exchange (ETDEWEB)

    Wu, G.; Dhanaraj, N.; Cooley, L.; Hicks, D.; Hahn, E.; Burk, D.; Muranyi, W.; Foley, N.; Edwards, H.; Harms, E.; Champion, M.; /Fermilab /Michigan State U.

    2009-06-01

    Mechanical tests of cavity-grade niobium samples were conducted to provide engineering information for the certification of 3rd-harmonic superconducting radio-frequency cavities and cryomodules. Large changes of mechanical properties occur throughout the cavity fabrication process due to the cold work introduced by forming, the heating introduced by electron beam welding, and the recovery of cold work during the anneal used to degas hydrogen after chemical processing. Data is provided here to show the different properties at various stages of fabrication, including both weld regions and samples from the bulk niobium far away from the weld. Measurements of RRR were used to assure that any contamination during annealing was negligible.

  18. Einstein's Materialism and Modern Tests of Quantum Mechanics

    Science.gov (United States)

    Vigier, J. P.

    After a presentation of Einstein's and Bohr's antagonistic point of view on the interpretation of Quantum Mechanics an illustration of their conflicting positions in the particular case of Young's double slit experiment is presented. It is then shown that in their most recent form (i. e. time dependent neutron interferometry) these experiments suggest (if one accepts absolute energymomentum conservation in all individual microprocesses) that Einstein was right in the Bohr-Einstein controversy.Translated AbstractEinsteins Materialismus und heutige Tests der QuantenmechanikNach einer Darstellung von Einsteins und Bohrs antagonistischen Standpunkten in der Interpretation der Quantenmechanik werden ihre widersprüchlichen Positionen im speziellen Fall des Youngschen Doppelspaltexperiments dargestellt. Es wird dann gezeigt, daß diese Experimente in ihrer neuesten Form (d. h. zeitabhängige Neutroneninterferometrie) Einstein in der Bohr-Einsteinkontroverse recht gaben (wenn man absolute Energie-Impulserhaltung bei allen individuellen Mikroprozessen annimmt).

  19. Design and experimental test to ecological bricks based on organic and inorganic materials

    OpenAIRE

    Pérez, Herminio; Pimentel, Kristi; De Meza, Olga; Hernández Korner, Mario

    2017-01-01

    This article describes the experimental design and testing of ecological blocks based on organic and inorganic materials. For the development of this project we formulated two experimental designs for the manufacture of blocks specifying the dimensions of the blocks, proportions, materials, and also the weight of those materials, then we brought those designs to the reality manufacturing 8 blocks for each experimental design. Later the testing of compressive strength of the blocks was made fo...

  20. A mucosa-mimetic material for the mucoadhesion testing of thermogelling semi-solids

    OpenAIRE

    da Silva, Jéssica Bassi; Khutoryanskiy, Vitaliy V.; Bruschi, Marcos L.; Cook, Michael T.

    2017-01-01

    Mucosa-mimetic materials are synthetic substrates which aim to replace animal tissue in mucoadhesion experiments. One potential mucosa-mimetic material is a hydrogel comprised of N-acryloyl-d-glucosamine and 2-hydroxyethylmethacrylate, which has been investigated as a surrogate for animal mucosae in the mucoadhesion testing of tablets and solution formulations. This study aims to investigate the efficacy of this mucosa-mimetic material in the testing of thermogelling semi-solid formulations, ...

  1. Test methods for the dynamic mechanical properties of polymeric materials. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Baker, G.K.

    1980-06-01

    Various test geometries and procedures for the dynamic mechanical analysis of polymers employing a mechanical spectrometer have been evaluated. The methods and materials included in this work are forced torsional pendulum testing of Kevlar/epoxy laminates and rigid urethane foams, oscillatory parallel plate testing to determine the kinetics of the cure of VCE with Hylene MP, oscillatory compressive testing of B-3223 cellular silicone, and oscillatory tensile testing of Silastic E and single Kevlar filaments. Fundamental dynamic mechanical properties, including the storage and loss moduli and loss tangent of the materials tested, were determined as a function of temperature and sometimes of frequency.

  2. Influence of heat treatment and indenter tip material on depth sensing hardness tests at high temperatures of fusion relevant materials

    International Nuclear Information System (INIS)

    Bredl, Julian; Dany, Manuel; Albinski, Bartlomiej; Schneider, Hans-Christian; Kraft, Oliver

    2015-01-01

    Highlights: • Operation of a custom-made indentation device designed for test temperatures up to 650 °C and a remote handled operation in a Hot Cell. • Instrumented indentation and conventional hardness testing of unirradiated MANET II and EUROFER. • Comparison of diamond and sapphire as indenter tip materials. - Abstract: The instrumented indentation is a suitable method for testing of even small neutron-irradiated specimens. From the continuously recorded indentation depth and the indentation force, it is possible to deduce mechanical parameters of the tested material. In this paper, a brief description of the high temperature device is given and representative results are presented. In the study, unirradiated steels are investigated by instrumented indentation at temperatures up to 500 °C. It is shown that the hardness is highly depending on the testing-temperature and can be correlated to the results of conventional tensile testing experiments. A not negligible influence of the indenter tip material is observed. The results show the functionality of the high-temperature indentation device.

  3. A measurement method for piezoelectric material properties under longitudinal compressive stress–-a compression test method for thin piezoelectric materials

    International Nuclear Information System (INIS)

    Kang, Lae-Hyong; Lee, Dae-Oen; Han, Jae-Hung

    2011-01-01

    We introduce a new compression test method for piezoelectric materials to investigate changes in piezoelectric properties under the compressive stress condition. Until now, compression tests of piezoelectric materials have been generally conducted using bulky piezoelectric ceramics and pressure block. The conventional method using the pressure block for thin piezoelectric patches, which are used in unimorph or bimorph actuators, is prone to unwanted bending and buckling. In addition, due to the constrained boundaries at both ends, the observed piezoelectric behavior contains boundary effects. In order to avoid these problems, the proposed method employs two guide plates with initial longitudinal tensile stress. By removing the tensile stress after bonding a piezoelectric material between the guide layers, longitudinal compressive stress is induced in the piezoelectric layer. Using the compression test specimens, two important properties, which govern the actuation performance of the piezoelectric material, the piezoelectric strain coefficients and the elastic modulus, are measured to evaluate the effects of applied electric fields and re-poling. The results show that the piezoelectric strain coefficient d 31 increases and the elastic modulus decreases when high voltage is applied to PZT5A, and the compression in the longitudinal direction decreases the piezoelectric strain coefficient d 31 but does not affect the elastic modulus. We also found that the re-poling of the piezoelectric material increases the elastic modulus, but the piezoelectric strain coefficient d 31 is not changed much (slightly increased) by re-poling

  4. Introduction to biomedical optics

    CERN Document Server

    Splinter, Robert

    2006-01-01

    GENERAL BIOMEDICAL OPTICS THEORYIntroduction to the Use of Light for Diagnostic and Therapeutic ModalitiesWhat Is Biomedical Optics?Biomedical Optics TimelineElementary Optical DiscoveriesHistorical Events in Therapeutic and Diagnostic Use of LightLight SourcesCurrent State of the ArtSummaryAdditional ReadingProblemsReview of Optical Principles: Fundamental Electromagnetic Theory and Description of Light SourcesDefinitions in OpticsKirchhoff's Laws of RadiationElectromagnetic Wave TheoryLight SourcesApplications of Various LasersSummaryAdditional ReadingProblemsReview of Optical Principles: Classical OpticsGeometrical OpticsOther Optical PrinciplesQuantum PhysicsGaussian OpticsSummaryAdditional ReadingProblemsReview of Optical Interaction PropertiesAbsorption and ScatteringSummaryAdditional ReadingProblemsLight-Tissue Interaction VariablesLaser VariablesTissue VariablesLight Transportation TheoryLight Propagation under Dominant AbsorptionSummaryNomenclatureAdditional ReadingProblemsLight-Tissue Interaction Th...

  5. Development and Execution of a Large-scale DDT Tube Test for IHE Material Qualification

    Energy Technology Data Exchange (ETDEWEB)

    Parker, Gary Robert [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Broilo, Robert M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Lopez-Pulliam, Ian Daniel [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Vaughan, Larry Dean [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-10-24

    Insensitive High Explosive (IHE) Materials are defined in Chapter IX of the DOE Explosive Safety Standard (DOE-STD-1212-2012) as being materials that are massdetonable explosives that are so insensitive that the probability of accidental initiation or transition from burning to detonation is negligible1. There are currently a number of tests included in the standard that are required to qualify a material as IHE, however, none of the tests directly evaluate for the transition from burning to detonation (aka deflagration-to-detonation transition, DDT). Currently, there is a DOE complex-wide effort to revisit the IHE definition in DOE-STD-1212-2012 and change the qualification requirements. The proposal lays out a new approach, requiring fewer, but more appropriate tests, for IHE Material qualification. One of these new tests is the Deflagration-to-Detonation Test. According to the redefinition proposal, the purpose of the new deflagration-todetonation test is “to demonstrate that an IHE material will not undergo deflagration-to-detonation under stockpile relevant conditions of scale, confinement, and material condition. Inherent in this test design is the assumption that ignition does occur, with onset of deflagration. The test design will incorporate large margins and replicates to account for the stochastic nature of DDT events.” In short, the philosophy behind this approach is that if a material fails to undergo DDT in a significant over-test, then it is extremely unlikely to do so in realistic conditions. This effort will be valuable for the B61 LEP to satisfy their need qualify the new production lots of PBX 9502. The work described in this report is intended as a preliminary investigation to support the proposed design of an overly conservative, easily fielded DDT test for updated IHE Material Qualification standard. Specifically, we evaluated the aspects of confinement, geometry, material morphology and temperature. We also developed and tested a

  6. Laboratory compaction test methods and results compared with attainable field densities on subbase materials

    International Nuclear Information System (INIS)

    Hoffman, G.L.; Cumberledge, G.; Koehler, W.C.

    1976-01-01

    With the extensive use of aggregate material in highway construction (primarily subbase) in Pennsylvania, the Pennsylvania Department of Transportation (PennDOT) initiated an indepth analysis of results of laboratory and field compaction tests on aggregates. This study determined what field and laboratory tests are best correlated to produce the optimum compaction control technique for subbase materials. Results of approximately 500 sand cone and nuclear field densities in crushed limestone, gravel, and slag material at 17 construction sites throughout the state are summarized and compared. Laboratory density tests on material from each of these field test sites include vibratory, standard moisture-density, modified moisture density, the Marshall test, and the vibratory hammer test. Regression correlation analyses are performed between maximum attainable field and laboratory densities. Estimating linear equations for predicting relationships between field and laboratory maximum densities are developed and their significance is discussed

  7. Comparison of irradiated 15Kh2MFA material mechanical properties using conventional testing methods and innovative approach of small punch testing (SPT) and automated ball indentation (ABIT)

    Science.gov (United States)

    Kopriva, R.; Petelova, P.; Eliasova, I.; Kytka, M.; Culek, M.

    2017-02-01

    Article describes two innovative testing methods - Small Punch Testing (SPT) and Automated Ball Indentation Test (ABIT) - which are based on the determination and evaluation of material properties from miniaturized testing specimens. These methods are very promising due to minimum material needed for testing and also in case of testing highly irradiated materials of components that are not included in standard surveillance programs. The test results were obtained for reactor pressure vessel (RPV) base material 15Ch2MFA in both states - initial unirradiated and irradiated. Subsequently results were compared with standard tensile tests to prove applicability of these testing methods for the evaluation of degradation of irradiated structural materials of nuclear power plants.

  8. Advances in biomedical engineering

    CERN Document Server

    Brown, J H U

    1976-01-01

    Advances in Biomedical Engineering, Volume 6, is a collection of papers that discusses the role of integrated electronics in medical systems and the usage of biological mathematical models in biological systems. Other papers deal with the health care systems, the problems and methods of approach toward rehabilitation, as well as the future of biomedical engineering. One paper discusses the use of system identification as it applies to biological systems to estimate the values of a number of parameters (for example, resistance, diffusion coefficients) by indirect means. More particularly, the i

  9. Biomedical enhancements as justice.

    Science.gov (United States)

    Nam, Jeesoo

    2015-02-01

    Biomedical enhancements, the applications of medical technology to make better those who are neither ill nor deficient, have made great strides in the past few decades. Using Amartya Sen's capability approach as my framework, I argue in this article that far from being simply permissible, we have a prima facie moral obligation to use these new developments for the end goal of promoting social justice. In terms of both range and magnitude, the use of biomedical enhancements will mark a radical advance in how we compensate the most disadvantaged members of society. © 2013 John Wiley & Sons Ltd.

  10. Piezoelectric nanomaterials for biomedical applications

    CERN Document Server

    Menciassi, Arianna

    2012-01-01

    Nanoscale structures and materials have been explored in many biological applications because of their novel and impressive physical and chemical properties. Such properties allow remarkable opportunities to study and interact with complex biological processes. This book analyses the state of the art of piezoelectric nanomaterials and introduces their applications in the biomedical field. Despite their impressive potentials, piezoelectric materials have not yet received significant attention for bio-applications. This book shows that the exploitation of piezoelectric nanoparticles in nanomedicine is possible and realistic, and their impressive physical properties can be useful for several applications, ranging from sensors and transducers for the detection of biomolecules to “sensible” substrates for tissue engineering or cell stimulation.

  11. Synthesis and properties of materials based on SiO2-CaO-P2O5-TiO2 for biomedical usage

    Science.gov (United States)

    Borilo, Lyudmila; Lyutova, Ekaterina

    2017-11-01

    Thin films of film-forming solutions based on calcium chloride, tetraethoxysilane, tetrabutoxytitanium, and phosphoric acid have been synthesized in the paper. Thin films were obtained from film-forming solutions on single-crystal silicon substrates (model substrate) by centrifugation at a rotation speed of 3000 revolutions/min. Followed by heat treatment at 60 ° C for 20 minutes and at 600 and 800 °C for 1 hour. The solutions are suitable for obtaining uniform films up to 5 days. The properties of the material were investigated by the methods of infrared spectroscopy, X-ray phase analysis, and thermal analysis. Biological activity was studied under artificial conditions in the simulation body fluid medium. With an increase in the weight content of titanium oxide in the system up to 10%, the bioactivity of the material increases.

  12. Validation of the material point method and plasticity with Taylor impact tests

    OpenAIRE

    Banerjee, Biswajit

    2012-01-01

    Taylor impacts tests were originally devised to determine the dynamic yield strength of materials at moderate strain rates. More recently, such tests have been used extensively to validate numerical codes for the simulation of plastic deformation. In this work, we use the material point method to simulate a number of Taylor impact tests to compare different Johnson-Cook, Mechanical Threshold Stress, and Steinberg-Guinan-Cochran plasticity models and the vob Mises and Gurson-Tvergaard-Needlema...

  13. State of the art report on the materials testing capabilities for IASCC susceptibility testing at SCK-CEN

    Energy Technology Data Exchange (ETDEWEB)

    Bosch, R.-W.; Boydens, P.; Vankeerbergen, R.; Van Nieuwenhove, R.; Van Dyck, S

    1999-08-01

    An overview of the current IASCC testing facilities at the Belgian Nuclear Research Centre SCK-CEN is given. The testing techniques are reviewed, and their capabilities as well as their limitations are discussed. Possible future developments in testing techniques are discussed. IASCC is caused by a complex interaction between materials, its environment and mechanical stresses. Characterisation techniques assessing mechanical stresses as well as electrochemical and microstructural characteristics are reported on.

  14. Potential of Starch Nanocomposites for Biomedical Applications

    Science.gov (United States)

    Zakaria, N. H.; Muhammad, N.; Abdullah, M. M. A. B.

    2017-06-01

    In recent years, the development of biodegradable materials from renewable sources based on polymeric biomaterials have grown rapidly due to increase environmental concerns and the shortage of petroleum sources. In this regard, naturally renewable polymers such as starch has shown great potential as environmental friendly materials. Besides, the unique properties of starch such as biodegradable and non-toxic, biocompatible and solubility make them useful for a various biomedical applications. Regardless of their unique properties, starch materials are known to have limitations in term of poor processability, low mechanical properties, poor long term stability and high water sensitivity. In order to overcome these limitations, the incorporation of nano size fillers into starch materials (nanocomposites) has been introduced. This review aims to give an overview about structure and characteristics of starch, modification of starch by nanocomposites and their potential for biomedical applications.

  15. Analysis of the NASA White Sands Test Facility (WSTF) Test System for Friction-Ignition of Metallic Materials

    Science.gov (United States)

    Shoffstall, Michael S.; Wilson, D. Bruce; Stoltzfus, Joel M.

    2000-01-01

    Friction is a known ignition source for metals in oxygen-enriched atmospheres. The test system developed by the NASA White Sands Test Facility in response to ASTM G-94 has been used successfully to determine the relative ignition from friction of numerous metallic materials and metallic materials pairs. These results have been ranked in terms of a pressure-velocity product (PV) as measured under the prescribed test conditions. A high value of 4.1(exp 8) watts per square meter for Inconel MA 754 is used to imply resistance to friction ignition, whereas a low value of 1.04(exp 8) watts per square meter for stainless steel 304 is taken as indicating material susceptible to friction ignition. No attempt has been made to relate PV values to other material properties. This work reports the analysis of the WSTF friction-ignition test system for producing fundamental properties of metallic materials relating to ignition through friction. Three materials, aluminum, titanium, and nickel were tested in the WSTF frictional ignition instrument system under atmospheres of oxygen or nitrogen. Test conditions were modified to reach a steady state of operation, that is applied, the force was reduced and the rotational speed was reduced. Additional temperature measurements were made on the stator sample. The aluminum immediately galled on contact (reproducible) and the test was stopped. Titanium immediately ignited as a result of non-uniform contact of the stator and rotor. This was reproducible. A portion of the stator sampled burned, but the test continued. Temperature measurements on the stator were used to validate the mathematical model used for estimating the interface (stator/rotor) temperature. These interface temperature measurements and the associate thermal flux into the stator were used to distinguish material-phase transitions, chemical reaction, and mechanical work. The mechanical work was used to analyze surface asperities in the materials and to estimate a

  16. Material characterization of Inconel 718 from free bulging test at high temperature

    Energy Technology Data Exchange (ETDEWEB)

    Yoo, Joon Tae; Yoon, Jong Hoon; Lee, Ho Sung [Korea Aerospace Research Institute, Daejeon (Korea, Republic of); Youn, Sung Kie [Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of)

    2012-07-15

    Macroscopic superplastic behavior of metallic or non metallic materials is usually represented by the strain rate sensitivity, and it can be determined by tensile tests in uniaxial stress state and bulging tests in multi axial stress state, which is the actual hot forming process. And macroscopic behavior of Non SPF grade materials could be described in a similar way as that of superplastic materials, including strain hardening, cavity and so on. In this study, the material characterization of non SPF grade Inconel 718 has been carried out to determine the material parameters for flow stress throughout free bulging test under constant temperature. The measured height of bulged plate during the test was used for estimation of strain rate sensitivity, strain hardening index and cavity volume fraction with the help of numerical analysis. The bulged height obtained from the simulation showed good agreement with the experimental findings. The effects of strain hardening and cavity volume fraction factor for flow stress were also compared.

  17. A mucosa-mimetic material for the mucoadhesion testing of thermogelling semi-solids.

    Science.gov (United States)

    da Silva, Jéssica Bassi; Khutoryanskiy, Vitaliy V; Bruschi, Marcos L; Cook, Michael T

    2017-08-07

    Mucosa-mimetic materials are synthetic substrates which aim to replace animal tissue in mucoadhesion experiments. One potential mucosa-mimetic material is a hydrogel comprised of N-acryloyl-d-glucosamine and 2-hydroxyethylmethacrylate, which has been investigated as a surrogate for animal mucosae in the mucoadhesion testing of tablets and solution formulations. This study aims to investigate the efficacy of this mucosa-mimetic material in the testing of thermogelling semi-solid formulations, which transition from solution to gel upon warming. Two methods for assessing mucoadhesion have been used; tensile testing and a flow-through system, which allow for investigation under dramatically different conditions. It was found that the mucosa-mimetic material was a good surrogate for buccal mucosa using both testing methods. This material may be used to replace animal tissue in these experiments, potentially reducing the number of laboratory animals used in studies of this type. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Biomedical engineering for health research and development.

    Science.gov (United States)

    Zhang, X-Y

    2015-01-01

    Biomedical engineering is a new area of research in medicine and biology, providing new concepts and designs for the diagnosis, treatment and prevention of various diseases. There are several types of biomedical engineering, such as tissue, genetic, neural and stem cells, as well as chemical and clinical engineering for health care. Many electronic and magnetic methods and equipments are used for the biomedical engineering such as Computed Tomography (CT) scans, Magnetic Resonance Imaging (MRI) scans, Electroencephalography (EEG), Ultrasound and regenerative medicine and stem cell cultures, preparations of artificial cells and organs, such as pancreas, urinary bladders, liver cells, and fibroblasts cells of foreskin and others. The principle of tissue engineering is described with various types of cells used for tissue engineering purposes. The use of several medical devices and bionics are mentioned with scaffold, cells and tissue cultures and various materials are used for biomedical engineering. The use of biomedical engineering methods is very important for the human health, and research and development of diseases. The bioreactors and preparations of artificial cells or tissues and organs are described here.

  19. Cyclotrons for clinical and biomedical research with PET

    International Nuclear Information System (INIS)

    Wolf, A.P.

    1987-01-01

    The purpose of this commentary is to present some background material on cyclotrons and other particle accelerators particularly with a view toward the considerations behind acquiring and installing such a machine for purely clinical and/or biomedical research use

  20. Ceramic Materials in a Ti–C–Co–Ca3(PO42–Ag–Mg System Obtained by MA SHS for the Deposition of Biomedical Coatings

    Directory of Open Access Journals (Sweden)

    Artem Potanin

    2017-09-01

    Full Text Available This study aimed to obtain biocompatible ceramic materials in a Ti–C–Co–Ca3(PO42–Ag–Mg system by the combustion mode of mechanically activated (MA reaction mixtures. The influence of the MA time on the reaction ability capability of the mixtures, on their structural and chemical homogeneity, on the combustion parameters and structural-phase conversions in the combustion wave, as well as on the structure and phase composition of the electrode materials has been researched. It was found that the intense treatment of powder mixtures causes plastic deformation of components, the formation of lamellar composite granules, a reduction in the sizes of coherent scattering regions, and also the formation of minor amounts of products. The influence of the activation duration of the ignition temperature and heat release during the combustion of the reaction mixtures was studied. By the method of quenching the combustion front, it was demonstrated that in a combustion wave, chemical transformations occur within the lamellar structures formed during the process of mechanoactivation. It was shown that in the combustion wave, parallel chemical reactions of Ti with C as well as Ti with Co and Ca3(PO42 occur, with a Ti–Co-based melt forming the reaction surface. Ceramic electrodes with different contents of Ag and Mg were synthesized by force self-propagating high-temperature synthesis (SHS-pressing technology using the MA mixtures. The microstructure of the materials consisted of round-shaped grains of nonstoichiometric titanium carbide TiCx grains, intermetallic matrix (TiCo, TiCo2, CoTiP, inclusions of Ca and Mg oxides, and grains of the Ag-based solid solution. An increased content of Ag and Mg in the composition of the electrodes, as well as an increased MA duration, leads to an enlargement of the inclusions of the Ag-containing phase size and deterioration in the uniformity of their distribution.