WorldWideScience

Sample records for biology nato advanced

  1. NATO Advanced Research Workshop

    CERN Document Server

    Wiedemann, Helmut

    2006-01-01

    This book covers latest development in theory and experiments of unconventional radiation production. Specifically, the generation of Tera-Hertz and X-ray radiation from low energy electron beams in the form of Channeling, Transition, Diffraction, Cherenkov, Smith-Purcell, PXR and Crystalline Undulator Radiation are presented. Material characteristics like thin targets, curved or bend crystals, inhomogeneous and left handed materials, multilayers as well as stimulation by external radiation are covered to demonstrate their influence in these processes. Novel ideas are offered on the use of such radiation in detectors and particle beam monitor development with improved energy or time resolution. The book assumes some familiarity of the reader with theoretical concepts underlying these phenomena and is therefore of primary use to the practicing scientist. More fundamental discussions of these phenomena can be found in the 2002 monograph "Electron-Photon Interaction in Dense Media" within the NATO Science Series...

  2. NATO Conference on Materials for Advanced Batteries

    CERN Document Server

    Broadhead, J; Steele, B

    1980-01-01

    The idea of a NATO Science Committee Institute on "Materials for Advanced Batteries" was suggested to JB and DWM by Dr. A. G. Chynoweth. His idea was to bring together experts in the field over the entire spectrum of pure research to applied research in order to familiarize everyone with potentially interesting new systems and the problems involved in their development. Dr. M. C. B. Hotz and Professor M. N. Ozdas were instrumental in helping organize this meeting as a NATO Advanced Science Institute. An organlzlng committee consisting of the three of us along with W. A. Adams, U. v Alpen, J. Casey and J. Rouxel organized the program. The program consisted of plenary talks and poster papers which are included in this volume. Nearly half the time of the conference was spent in study groups. The aim of these groups was to assess the status of several key aspects of batteries and prospects for research opportunities in each. The study groups and their chairmen were: Current status and new systems J. Broadhead Hig...

  3. NATO Advanced Study Institute on Mixed-Valence Compounds : Theory and Applications in Chemistry, Physics, Geology, and Biology

    CERN Document Server

    1980-01-01

    It has been a decade since two seminal reviews demonstrated that mixed-valence compounds share many unique and fascinating features. The insight pro­ vided by those early works has promoted a great deal of both experimental and theoretical study. As a result of extensive efforts, our understanding of the bonding and properties of mixed-valence compounds has advanced substantially. There has been no compre­ hensive treatment of mixed-valence compounds since 1967, and the meeting convened at Oxford in September, 1979, provided a unique opportunity to examine the subject and its many ramifications. Mixed-valence compounds play an important role in many fields. Although the major impact of the subject has been in chemistry, its importance has become increasingly clear in solid state physics, geology, and biology. Extensive interest and effort in the field of molecular metals has demonstrated that mixed-valency is a prerequisite for high elec­ trical conductivity. The intense colors of many minerals have been s...

  4. NATO Advanced Study Institute on Advanced Physical Oceanographic Numerical Modelling

    CERN Document Server

    1986-01-01

    This book is a direct result of the NATO Advanced Study Institute held in Banyuls-sur-mer, France, June 1985. The Institute had the same title as this book. It was held at Laboratoire Arago. Eighty lecturers and students from almost all NATO countries attended. The purpose was to review the state of the art of physical oceanographic numerical modelling including the parameterization of physical processes. This book represents a cross-section of the lectures presented at the ASI. It covers elementary mathematical aspects through large scale practical aspects of ocean circulation calculations. It does not encompass every facet of the science of oceanographic modelling. We have, however, captured most of the essence of mesoscale and large-scale ocean modelling for blue water and shallow seas. There have been considerable advances in modelling coastal circulation which are not included. The methods section does not include important material on phase and group velocity errors, selection of grid structures, advanc...

  5. NATO Advanced Study Institute on Superconducting Electronics

    CERN Document Server

    Nisenhoff, Martin; Superconducting Electronics

    1989-01-01

    The genesis of the NATO Advanced Study Institute (ASI) upon which this volume is based, occurred during the summer of 1986 when we came to the realization that there had been significant progress during the early 1980's in the field of superconducting electronics and in applications of this technology. Despite this progress, there was a perception among many engineers and scientists that, with the possible exception of a limited number of esoteric fundamental studies and applications (e.g., the Josephson voltage standard or the SQUID magnetometer), there was no significant future for electronic systems incorporating superconducting elements. One of the major reasons for this perception was the aversion to handling liquid helium or including a closed-cycle helium liquefier. In addition, many critics felt that IBM's cancellation of its superconducting computer project in 1983 was "proof" that superconductors could not possibly compete with semiconductors in high-speed signal processing. From our persp...

  6. NATO Advanced Study Institute on Metal Hydrides

    CERN Document Server

    1981-01-01

    In the last five years, the study of metal hydrides has ex­ panded enormously due to the potential technological importance of this class of materials in hydrogen based energy conversion schemes. The scope of this activity has been worldwide among the industrially advanced nations. There has been a consensus among researchers in both fundamental and applied areas that a more basic understanding of the properties of metal/hydrogen syster;,s is required in order to provide a rational basis for the selection of materials for specific applications. The current worldwide need for and interest in research in metal hydrides indicated the timeliness of an Advanced Study Insti­ tute to provide an in-depth view of the field for those active in its various aspects. The inclusion of speakers from non-NATO coun­ tries provided the opportunity for cross-fertilization of ideas for future research. While the emphasis of the Institute was on basic properties, there was a conscious effort to stimulate interest in the applic...

  7. NATO

    DEFF Research Database (Denmark)

    Breitenbauch, Henrik Ø.

    2014-01-01

    After Ukraine, conventional deterrence will be the main purpose of NATO’s armed forces. NATO contingency planning, operational training and defense planning will all revolve around conventional deterrence. Russia’s ready use of force in Ukraine, Georgia and beyond shows that its non-NATO neighbor....... Could Moscow apply the same measures in a NATO country with a significant Russian minority population, such as Latvia? This question should keep NATO leaders up at night and by the morning they should realize that the solution is conventional deterrence....

  8. NATO Advanced Study Institute on Advances in Chemical Reaction Dynamics

    CERN Document Server

    Capellos, Christos

    1986-01-01

    This book contains the formal lectures and contributed papers presented at the NATO Advanced Study Institute on. the Advances in Chemical Reaction Dynamics. The meeting convened at the city of Iraklion, Crete, Greece on 25 August 1985 and continued to 7 September 1985. The material presented describes the fundamental and recent advances in experimental and theoretical aspects of, reaction dynamics. A large section is devoted to electronically excited states, ionic species, and free radicals, relevant to chemical sys­ tems. In addition recent advances in gas phase polymerization, formation of clusters, and energy release processes in energetic materials were presented. Selected papers deal with topics such as the dynamics of electric field effects in low polar solutions, high electric field perturbations and relaxation of dipole equilibria, correlation in picosecond/laser pulse scattering, and applications to fast reaction dynamics. Picosecond transient Raman spectroscopy which has been used for the elucidati...

  9. NATO Advanced Study Institute on Advances in Microlocal Analysis

    CERN Document Server

    1986-01-01

    The 1985 Castel vecchio-Pas coli NATO Advanced Study Institute is aimed to complete the trilogy with the two former institutes I organized : "Boundary Value Problem for Evolution Partial Differential Operators", Liege, 1976 and "Singularities in Boundary Value Problems", Maratea, 1980. It was indeed necessary to record the considerable progress realized in the field of the propagation of singularities of Schwartz Distri­ butions which led recently to the birth of a new branch of Mathema­ tical Analysis called Microlocal Analysis. Most of this theory was mainly built to be applied to distribution solutions of linear partial differential problems. A large part of this institute still went in this direction. But, on the other hand, it was also time to explore the new trend to use microlocal analysis In non linear differential problems. I hope that the Castelvecchio NATO ASI reached its purposes with the help of the more famous authorities in the field. The meeting was held in Tuscany (Italy) at Castelvecchio-P...

  10. NATO Advanced Research Institute on the Efficiency of Manufacturing Systems

    CERN Document Server

    Berg, C; French, D

    1983-01-01

    The Advanced Research Institute (A.R. 1.) on "the efficiency of Manufacturing Systems" was held under the auspices of the NATO Special Programm~ Panel on Systems Science as a part of the NATO Science Committee's continuous effort to promote the advancement of science through international co-operation. Advanced Research Institutes are organised for the purpose of bringing together experts in a particular field of interest to identify and make known the present state of knowledge in that area and, through informed debate, to make recommendations for directions for future research that would benefit the community at large. To this end two kinds of contribution were obtained by invitation. There were those papers which were about the current state of work in the area of manufacturing systems and its organisation; in addition three theme papers were presented to provide a stimulus to the discussion in terms of ways of thinking, both about the area and about the kind of research needed.

  11. NATO Advanced Study Institute on Methods in Computational Molecular Physics

    CERN Document Server

    Diercksen, Geerd

    1992-01-01

    This volume records the lectures given at a NATO Advanced Study Institute on Methods in Computational Molecular Physics held in Bad Windsheim, Germany, from 22nd July until 2nd. August, 1991. This NATO Advanced Study Institute sought to bridge the quite considerable gap which exist between the presentation of molecular electronic structure theory found in contemporary monographs such as, for example, McWeeny's Methods 0/ Molecular Quantum Mechanics (Academic Press, London, 1989) or Wilson's Electron correlation in moleeules (Clarendon Press, Oxford, 1984) and the realization of the sophisticated computational algorithms required for their practical application. It sought to underline the relation between the electronic structure problem and the study of nuc1ear motion. Software for performing molecular electronic structure calculations is now being applied in an increasingly wide range of fields in both the academic and the commercial sectors. Numerous applications are reported in areas as diverse as catalysi...

  12. Nato

    DEFF Research Database (Denmark)

    Brattberg, Erik; Breitenbauch, Henrik Ø.

    2015-01-01

    historia. Idag har Sverige en möjlighet att fatta ett beslut som inte bara skulle stärka vår egen säkerhet, utan även hela Östersjöregionens. Nordiskt försvarssamarbete skulle ha stor nytta av ett svenskt (och finskt) Natomedlemskap liksom det skulle förbättra Natos möjligheter att skydda Baltikum....

  13. NATO Advanced Research Institute on Search Theory and Applications

    CERN Document Server

    Stone, Lawrence

    1980-01-01

    The NATO Advanced Research Institute on Search Theory and Appli­ cations was held at the Hotel Algarve in Praia Da Rocha, Portugal, from March 26 through March 30, 1979, and was sponsored by the NATO Special Programme Panel on Systems Science. There were forty-one participants representing a wide range of backgrounds and interests. The purpose of the institute was to bring together people working in search theory and applications with potential users of search techniques to stimulate the increased application of recent­ ly developed search technology to civilian problems such as search and rescue, mineral exploration, surveillance, and fishing. Con­ versely, it was felt that by exposing search analysts to potential applications and new problems, they would be stimulated to develop new techniques for these applications and problems. The exchange of ideas and problems necessary to accomplish these goals was provided in the meeting workshops. There were three workshops, Search and Rescue, Exploration, and Sur...

  14. NATO Advanced Research Institute on Health Services Systems

    CERN Document Server

    Werff, Albert; Hirsch, Gary; Barnard, Keith

    1984-01-01

    The Advanced Research Institute on "Health Services Systems" was held under the auspices of the NATO Special Programme Panel on Systems Science as a part of the NATO Science Committee's continuous effort to promote the advancement of science through international cooperation. A special word is said in this respect supra by Pro­ fessor Checkland, Chairman of the Systems Science Panel. The Advanced Research Institute (ARI) was organized for the purpose of bringing together senior scientists to seek a consensus on the assessment of the present state of knowledge on the specific topic of "health services systems" and to present views and recom­ mendations for future health services research directions, which should be of value to both the scientific community and the people in charge of reorienting health services. The conference was structured so as to permit the assembly of a variety of complementary viewpoints through intensive group discussions to be the basis of this final report. Invitees were selected fr...

  15. NATO Advanced Study Institute on Spectroscopy

    Science.gov (United States)

    DiBartolo, Baldassare; Barnes, James (Technical Monitor)

    2001-01-01

    This booklet presents an account of the course 'Spectroscopy of Systems with Spatially Confined Structures' held in Erice-Sicily, Italy, from June 15 to June 30, 2001. This meeting was organized by the International School of Atomic and Molecular Spectroscopy of the 'Ettore Majorana' Centre for Scientific Culture. The purpose of this course was to present and discuss nanometer-scale physics, a rapidly progressing field. The top-down approach of semiconductor technology will soon meet the scales of the bottom-up approaches of supramolecular chemistry and of spatially localized excitations in ionic crystals. This course dealt with the fabrication, measurement and understanding of the relevant structures and brought together the scientific communities responsible for these development. The advances in this area of physics have already let to applications in optoelectronics and will likely lead to many more. The subjects of the course included spatially resolved structures such as quantum wells, quantum wires and quantum dots, single atoms and molecules, clusters, fractal systems, and the development of related techniques like near-field spectroscopy and confocal microscopy to study such systems.

  16. NATO Advanced Study Institute on Hamiltonian Dynamical Systems and Applications

    CERN Document Server

    2008-01-01

    Physical laws are for the most part expressed in terms of differential equations, and natural classes of these are in the form of conservation laws or of problems of the calculus of variations for an action functional. These problems can generally be posed as Hamiltonian systems, whether dynamical systems on finite dimensional phase space as in classical mechanics, or partial differential equations (PDE) which are naturally of infinitely many degrees of freedom. This volume is the collected and extended notes from the lectures on Hamiltonian dynamical systems and their applications that were given at the NATO Advanced Study Institute in Montreal in 2007. Many aspects of the modern theory of the subject were covered at this event, including low dimensional problems as well as the theory of Hamiltonian systems in infinite dimensional phase space; these are described in depth in this volume. Applications are also presented to several important areas of research, including problems in classical mechanics, continu...

  17. NATO Advanced Study Institute on Nonequilibrium Phonon Dynamics

    CERN Document Server

    1985-01-01

    Phonons are always present in the solid state even at an absolute temperature of 0 K where zero point vibrations still abound. Moreover, phonons interact with all other excitations of the solid state and, thereby, influence most of its properties. Historically experimental information on phonon transport came from measurements of thermal conductivity. Over the past two decades much more, and much more detailed, information on phonon transport and on many of the inherent phonon interaction processes have come to light from experiments which use nonequilibrium phonons to study their dynamics. The resultant research field has most recently blossomed with the development of ever more sophisticated experimental and theoretical methods which can be applied to it. In fact, the field is moving so rapidly that new members of the research community have difficulties in keeping up to date. This NATO Advanced Study Institute (ASI) was organized with the objective of overcoming the information barrier between those expert...

  18. NATO Advanced Study Institute on Recent Advances in the Modeling of Hydrologic Systems

    CERN Document Server

    O’Connell, P

    1991-01-01

    Modeling of the rainfall-runoff process is of both scientific and practical significance. Many of the currently used mathematical models of hydrologic systems were developed a genera­ tion ago. Much of the effort since then has focused on refining these models rather than on developing new models based on improved scientific understanding. In the past few years, however, a renewed effort has been made to improve both our fundamental understanding of hydrologic processes and to exploit technological advances in computing and remote sensing. It is against this background that the NATO Advanced Study Institute on Recent Advances in the Modeling of Hydrologic Systems was organized. The idea for holding a NATO ASI on this topic grew out of an informal discussion between one of the co-directors and Professor Francisco Nunes-Correia at a previous NATO ASI held at Tucson, Arizona in 1985. The Special Program Panel on Global Transport Mechanisms in the Geo-Sciences of the NATO Scientific Affairs Division agreed to sp...

  19. Forces, Growth and Form in Soft Condensed Matter: At the Interface between Physics and Biology NATO Advanced Study Institute, Geilo, Norway, 24 March - 3 April 2003

    Energy Technology Data Exchange (ETDEWEB)

    Helgesen, G. ed.

    2003-05-01

    The goal of this ASI was to bring together a group of disparate sciences to discuss areas of research related to competition between interactions of different ranges, for it is this that creates local structure on which complexity depends in soft condensed matter, biological systems and their synthetic models. The starting point, and the underlying theme throughout the ASI, was thus a thorough discussion of the relative role of the various fundamental interactions in such systems (electrostatic, hydrophobic, steric, conformational, van der Waals, etc.). The next focus was on how these competing interactions influence the form and topology of soft and biological matter, like polymers and proteins, leading to hierarchical structures in self-assembling systems and folding patterns sometimes described in terms of chirality, braids and knots. Finally, focus was on how the competing interactions influence various bio processes like genetic regulation and biological evolution taking place in systems like biopolymers, macromolecules and cell membranes. The report includes the abstracts of the posters presented, two of which are given in this database: (1) Precise characterisation of nano channels in track etched membranes by SAXS and SANS, and (2) Cisplatin binding to DNA: Structure, bonding and NMR properties from CarParrinello/Classical MD simulations.

  20. NATO Advanced Study Institute on Nano-Optics : Principles Enabling Basic Research and Applications

    CERN Document Server

    Collins, John; Silvestri, Luciano

    2017-01-01

    This book provides a comprehensive overview of nano-optics, including basic theory, experiment and applications, particularly in nanofabrication and optical characterization. The contributions clearly demonstrate how advances in nano-optics and photonics have stimulated progress in nanoscience and -fabrication, and vice versa. Their expert authors address topics such as three-dimensional optical lithography and microscopy beyond the Abbe diffraction limit, optical diagnostics and sensing, optical data- and telecommunications, energy-efficient lighting, and efficient solar energy conversion. Nano-optics emerges as a key enabling technology of the 21st century. This work will appeal to a wide readership, from physics through chemistry, to biology and engineering. The contributions that appear in this volume were presented at a NATO Advanced Study Institute held in Erice, 4-19 July, 2015.

  1. NATO Advanced Study Institute on Physics of New Laser Sources

    CERN Document Server

    Arecchi, F; Mooradian, Aram; Sona, Alberto

    1985-01-01

    This volume contains the lectures and seminars presented at the NATO Advanced Study Institute on "Physics of New Laser Sources", the twelfth course of the Europhysics School of Quantum Electronics, held under the supervision of the Quantum Electronics Division of the European Physical Society. The Institute was held at Centro "I Cappuccini" San Miniato, Tuscany, July 11-21, 1984. The Europhysics School of Quantum Electronics was started in 1970 with the aim of providing instruction for young researchers and advanced students already engaged in the area of quantum electronics or for those wishing to switch into this area after working previously in other areas. From the outset, the School has been under the direction of Prof. F. T. Arecchi, then at the University of Pavia, now at the University of Florence, and Dr. D. Roess of Heraeus, Hanau. In 1981, Prof. H. Walther, University of Munich and Max-Planck Institut fur Quantenoptik joined as co-director. Each year the Directors choose a subj~ct of particular int...

  2. NATO Advanced Study Institute on Atoms in Strong Fields

    CERN Document Server

    Clark, Charles; Nayfeh, Munir

    1990-01-01

    This book collects the lectures given at the NATO Advanced Study Institute on "Atoms in Strong Fields", which took place on the island of Kos, Greece, during the two weeks of October 9-21,1988. The designation "strong field" applies here to an external electromagnetic field that is sufficiently strong to cause highly nonlinear alterations in atomic or molecular struc­ ture and dynamics. The specific topics treated in this volume fall into two general cater­ gories, which are those for which strong field effects can be studied in detail in terrestrial laboratories: the dynamics of excited states in static or quasi-static electric and magnetic fields; and the interaction of atoms and molecules with intense laser radiation. In both areas there exist promising opportunities for research of a fundamental nature. An electric field of even a few volts per centimeter can be very strong on the atom­ ic scale, if it acts upon a weakly bound state. The study of Rydberg states with high reso­ lution laser spectroscop...

  3. NATO Advanced Study Institute on Turbulence, Weak and Strong

    CERN Document Server

    Cardoso, O

    1994-01-01

    The present volume comprises the contributions of some of the participants of the NATO Advance Studies Institute "Turbulence, Weak and Strong", held in Cargese, in August 1994. More than 70 scientists, from seniors to young students, have joined to­ gether to discuss and review new (and not so new) ideas and developments in the study of turbulence. One of the objectives of the School was to incorporate, in the same meeting, two aspects of turbulence, which are obviously linked, and which are often treated sep­ arately: fully developed turbulence (in two and three dimensions) and weak turbulence (essentially one and two-dimensional systems). The idea of preparing a dictionary rather than ordinary proceedings started from the feeling that the terminology of turbulence includes many long, technical, poorly evocative words, which are usually not understood by people exterior to the field, and which might be worth explaining. Students who start working in the field of turbulence face a sort of curious situation:...

  4. NATO Advanced Study Institute on Chemical Transport in Melasomatic Processes

    CERN Document Server

    1987-01-01

    As indicated on the title page, this book is an outgrowth of the NATO Advanced Study Institute (ASI) on Chemical Transport in Metasomatic Processes, which was held in Greece, June 3-16, 1985. The ASI consisted of five days of invited lectures, poster sessions, and discussion at the Club Poseidon near Loutraki, Corinthia, followed by a two-day field trip in Corinthia and Attica. The second week of the ASI consisted of an excursion aboard M/S Zeus, M/Y Dimitrios II, and the M/S Irini to four of the Cycladic Islands to visit, study, and sample outstanding exposures of metasomatic activity on Syros, Siphnos, Seriphos, and Naxos. Nine­ teen invited lectures and 10 session chairmen/discussion leaders participated in the ASI, which was attended by a total of 92 professional scientists and graduate stu­ dents from 15 countries. Seventeen of the invited lectures and the Field Excursion Guide are included in this volume, together with 10 papers and six abstracts representing contributed poster sessions. Although more...

  5. NATO Advanced Study Institute on Photophysical and Photochemical Tools in Polymer Science : Conformation, Dynamics, Morphology

    CERN Document Server

    1986-01-01

    In 1980 the New York Academy of Sciences sponsored a three-day conference on luminescence in biological and synthetic macromolecules. After that meeting, Professor Frans DeSchryver and I began to discuss the possibility of organizing a different kind of meeting, with time for both informal and in-depth discussions, to examine certain aspects of the application of fluorescence and phosphorescence spectroscopy to polymers. Our ideas developed through discussions with many others, particularly Professor Lucien Monnerie. By 1983, when we submitted our proposal to NATO for an Advanced Study Institute, the area had grown enormous ly. It is interesting in retrospect to look back on the points which emerged from these discussions as the basis around which the scientific program would be organized and the speakers chosen. We decided early on to focus on applications of these methods to provide information about polymer molecules and polymer systems: The topics would all relate to the conformation and dynamics of macro...

  6. NATO Advanced Research Workshop on Molecular Engineering for Advanced Materials

    CERN Document Server

    Schaumburg, Kjeld

    1995-01-01

    An important aspect of molecular engineering is the `property directed' synthesis of large molecules and molecular assemblies. Synthetic expertise has advanced to a state which allows the assembly of supramolecules containing thousands of atoms using a `construction kit' of molecular building blocks. Expansion in the field is driven by the appearance of new building blocks and by an improved understanding of the rules for joining them in the design of nanometer-sized devices. Another aspect is the transition from supramolecules to materials. At present no single molecule (however large) has been demonstrated to function as a device, but this appears to be only a matter of time. In all of this research, which has a strongly multidisciplinary character, both existing and yet to be developed analytical techniques are and will remain indispensable. All this and more is discussed in Molecular Engineering for Advanced Materials, which provides a masterly and up to date summary of one of the most challenging researc...

  7. NATO Advanced Research Institute on the Application of Systems Science to Energy Policy Planning

    CERN Document Server

    Cherniavsky, E; Laughton, M; Ruff, L

    1981-01-01

    The Advanced Research Institute (ARI) on "The Application of Systems Science to Energy Policy Planning" was held under the auspices of the NATO Special Programme Panel on Systems Science in collaboration with the National Center for Analysis of Energy Sys­ tems, Brookhaven National Laboratory, USA, as a part of the NATO Science Committee's continuous effort to promote the advancement of science through international cooperation. Advanced Research Institutes are sponsored by the NATO Science Committee for the purposes of bringing together senior scientists to seek consensus on an assessment of the present state of knowl­ edge on a specific topic and to make recommendations for future research directions. Meetings are structured to encourage inten­ sive group discussion. Invitees are carefully selected so that the group as a whole will contain the experience and expertise neces­ sary to make the conclusions valid and significant. A final report is published presenting the various viewpoints and conclusions....

  8. NATO Advanced Study Institute on Physics of Submicron Semiconductor Devices

    CERN Document Server

    Ferry, David; Jacoboni, C

    1988-01-01

    The papers contained in the volume represent lectures delivered as a 1983 NATO ASI, held at Urbino, Italy. The lecture series was designed to identify the key submicron and ultrasubmicron device physics, transport, materials and contact issues. Nonequilibrium transport, quantum transport, interfacial and size constraints issues were also highlighted. The ASI was supported by NATO and the European Research Office. H. L. Grubin D. K. Ferry C. Jacoboni v CONTENTS MODELLING OF SUB-MICRON DEVICES.................. .......... 1 E. Constant BOLTZMANN TRANSPORT EQUATION... ... ...... .................... 33 K. Hess TRANSPORT AND MATERIAL CONSIDERATIONS FOR SUBMICRON DEVICES. . .. . . . . .. . . . .. . .. . .... ... .. . . . .. . . . .. . . . . . . . . . . 45 H. L. Grubin EPITAXIAL GROWTH FOR SUB MICRON STRUCTURES.................. 179 C. E. C. Wood INSULATOR/SEMICONDUCTOR INTERFACES.......................... 195 C. W. Wilms en THEORY OF THE ELECTRONIC STRUCTURE OF SEMICONDUCTOR SURFACES AND INTERFACES...................

  9. NATO Advanced Study Institute on Relativistic and Electron Correlation Effects in Molecules and Solids

    CERN Document Server

    1994-01-01

    The NATO Advanced Study Institute (ASI) on "R@lativistic and Electron Correlation Effects in Molecules and Solids", co-sponsored by Simon Fraser University (SFU) and the Natural Sciences and Engineering Research Council of Canada (NSERC) was held Aug 10- 21, 1992 at the University of British Columbia (UBC), Vancouver, Canada. A total of 90 lecturers and students with backgrounds in Chemistry, Physics, Mathematics and various interdisciplinary subjects attended the ASI. In my proposal submitted to NATO for financial support for this ASI, I pointed out that a NATO ASI on the effects of relativity in many-electron systems was held ten years ago, [See G.L. Malli, (ed) Relativistic Effects in Atoms, Molecules and Solids, Plenum Press, Vol B87, New York, 1983]. Moreover, at a NATO Advanced Research Workshop (ARW) on advanced methods for molecular electronic structure "an assessment of state-of­ the-art of Electron Correlation ... " was carried out [see C.E. Dykstra, (ed), Advanced Theories and Computational Approa...

  10. NATO Advanced Research Workshop on Frontiers in Polymerization Catalysis and Polymer Synthesis

    CERN Document Server

    Guyot, A

    1987-01-01

    Due to their specific properties, polymers with well-defined structures have been receiving increasing attention over the last several years. Owing to the wide variability of their properties, these specialty polymers have been used in various areas from biomedical engineering to electronics or energy applications. The synthesis of such polymers necessi­ tates the use of new methods of polymerization which derived from an insight into the mechanism of polymerization reactions. A NATO Advanced Research Workshop on "Frontiers in Polymerization Catalysis and Polymer Synthesis" was held in BANDOl (FRANCE) in February 1987. Its aim was to assess the new polymerization methods, as well as the latest advances in the mechanisms of conventional polymerization reactions together with their applications to the synthesis of new macromolecular structures. The financial support from the NATO Scientific Affairs Division which covered the "lecturers' accomodation and travel expenses as well as the organization charges of th...

  11. NATO Advanced Research Workshop on the Mechanisms of Reactions of Organometallic Compounds with Surfaces

    CERN Document Server

    Williams, J

    1989-01-01

    A NATO Advanced Research Workshop on the "Mechanisms of Reactions of Organometallic Compounds with Surfaces" was held in St. Andrews, Scotland in June 1988. Many of the leading international researchers in this area were present at the workshop and all made oral presentations of their results. In addition, significant amounts of time were set aside for Round Table discussions, in which smaller groups considered the current status of mechanistic knowledge, identified areas of dispute or disagreement, and proposed experiments that need to be carried out to resolve such disputes so as to advance our understanding of this important research area. All the papers presented at the workshop are collected in this volume, together with summaries of the conclusions reached at the Round Table discussions. The workshop could not have taken place without financial support from NATO, and donations were also received from Associated Octel, Ltd., STC Ltd., and Epichem Ltd., for which the organisers are very grateful. The orga...

  12. NATO Advanced Study Institute on Pollutants from Combustion Formation and Impact on Atmospheric Chemistry

    CERN Document Server

    2000-01-01

    This volume is based on the lectures presented at the NATO Advanced Study Institute: (ASI) «Pollutants Formation from Combustion. Formation Mechanisms and Impact on th th Atmospheric Chemistry» held in Maratea, Italy, from 13 to 26 september 1998. Preservation of the environment is of increasing concern in individual countries but also at continental or world scales. The structure of a NATO ASI which involve lecturers and participants of different nationalities was thought as especially well suited to address environmental issues. As combustion is known to substantially contribute to the damaging of the atmosphere, it was natural to concentrate the ASI program on reviewing the currently available knowledge of the formation mechanisms of the main pollutants liberated by combustion systems. In most situations, pollutants are present as trace components and their formation and removal is strongly conditioned by the chemical reactions initiated by fuel consumption. Therefore specific lectures were aimed at defi...

  13. NATO Advanced Study Institute on Electronic Structure of Polymers and Molecular Crystals

    CERN Document Server

    Ladik, János

    1975-01-01

    The NATO Advanced Study Institute on "Electronic Structure of Polymers and Molecular Crystals" was held at the Facultes Universi­ taires de Namur (F.U.N.) from September 1st till September 14th, 1974. We wish to express our appreciation to the NATO Scientific Affairs Division whose generous support made this Institute possible and to the Facultes Universitaires de Namur and the Societe Chimique de Belgique which provided fellowships and travel grants to a number of students. This volume contains the main lectures about the basic principles of the field and about different recent developments of the theory of the electronic structure of polymers and molecular crystals. The school started with the presentation of the basic SCF-LCAO theory of the electronic structure of periodic polymers and molecular crystals (contributions by Ladik, Andre & Delhalle) showing how a combination of quantum chemical and solid state physical methods can provide band structures for these systems. The numerical aspects of these ...

  14. NATO Advanced Study Institute on Low Temperature Molecular Spectroscopy

    CERN Document Server

    1996-01-01

    Molecular spectroscopy has achieved rapid and significant progress in recent years, the low temperature techniques in particular having proved very useful for the study of reactive species, phase transitions, molecular clusters and crystals, superconductors and semiconductors, biochemical systems, astrophysical problems, etc. The widening range of applications has been accompanied by significant improvements in experimental methods, and low temperature molecular spectroscopy has been revealed as the best technique, in many cases, to establish the connection between experiment and theoretical calculations. This, in turn, has led to a rapidly increasing ability to predict molecular spectroscopic properties. The combination of an advanced tutorial standpoint with an emphasis on recent advances and new perspectives in both experimental and theoretical molecular spectroscopy contained in this book offers the reader insight into a wide range of techniques, particular emphasis being given to supersonic jet and matri...

  15. [NATO international advanced course on best way of training for mass casualty situations].

    Science.gov (United States)

    Klein, L; Michaelson, M

    2010-07-01

    NATO Advanced Training Course on Best Way of Training for Mass Casualty Situations was held in Haifa, Israel in November 16-18, 2009. In total, 22 participants from 8 countries of the Partnership for Peace and Mediterranean Dialogue Programmes attended the course. The participants, divided within three groups, discussed and practised the training methods for the preshospital aspect, the hospital aspect and the non-conventional aspect of the mass casualty management. An international team of experts, among others, used following teaching methods: general lectures, guided discussions, utilization of advanced multimedia tools, tabletop drills, and large scale drill as training tools. The trainees also learned about medical and clinical simulation as a training tool, and subsequently practiced it. A mass casualty drill was held in Rambam Health Care Campus at the end of the Course. The trainees of the course participated as observers and reviewers in the drill, and debriefed it together with Rambam medical staff. Realisation of the successful course was made possible by utilizing a grant of the NATO Science for Peace and Security Programme.

  16. NATO Advanced Research Workshop on Homogeneous and Heterogeneous Photocatalysis

    CERN Document Server

    Serpone, Nick

    1986-01-01

    Ever since the oil crisis of 1973, researchers in various fields of chemistry have proposed various schemes to conserve energy, as well to convert the sun's abundant and limitless supply of energy to produce chemical fuels (e. g. , hydrogen from water, . •. ). The enthusiasm had no previous parallel in the mid-1970's. Unfortunately, despite the several good proposals, the results have proven - in retrospect - somewhat disappointing from an economic viable point of view. The reasons for the meagre results are manyfold not the least of which are the experimental difficulties encountered in storage systems. Moreover, the lack of a concerted, well orchestrated interdisciplinary approach has been significant. By contrast, the chemical advances made in the understanding of the processes involved in such schemes have been phenomenal. A recent book on this issue ( M. Gratzel, Energy Resources through Photochemistry and Catalysis, 1983) is witness to the various efforts and approaches taken by researchers. In the re...

  17. NATO Advanced Study Institute on Buoyant Convection in Geophysical Flows

    CERN Document Server

    Fedorovich, E; Viegas, D; Wyngaard, J

    1998-01-01

    Studies of convection in geophysical flows constitute an advanced and rapidly developing area of research that is relevant to problems of the natural environment. During the last decade, significant progress has been achieved in the field as a result of both experimental studies and numerical modelling. This led to the principal revision of the widely held view on buoyancy-driven turbulent flows comprising an organised mean component with superimposed chaotic turbulence. An intermediate type of motion, represented by coherent structures, has been found to play a key role in geophysical boundary layers and in larger scale atmospheric and hydrospheric circulations driven by buoyant forcing. New aspects of the interaction between convective motions and rotation have recently been discovered and investigated. Extensive experimental data have also been collected on the role of convection in cloud dynamics and microphysics. New theoretical concepts and approaches have been outlined regarding scaling and parameteriz...

  18. NATO Advanced Research Workshop on The Chemistry of Weathering

    CERN Document Server

    1985-01-01

    Several important developments in our understanding of the chemistry of weathering have occurred in the last few years: 1. There has been a major breakthrough in our understanding of the mechanisms controlling the kinetics of sil icate dissolution, and there have been major advances in computer modeling of weathering processes. 2. There has been a growing recognition of the importance of organic solutes in the weathering process, and hence of the inter-relationships between mineral weathering and the terrestrial ecosystem. 3. The impact of acid deposition ("acid rain") has been widely recognized. The processes by which acid deposition is neutral ized are closely related to the processes of normal chemical weathering; an understanding of the chemistry of weathering is thus essential for predicting the effects of acid deposition. 4. More high-qual ity data have become available on the chemical dynamics of smal I watersheds and large river systems, which represent the integrated effects of chemical weathering.

  19. NATO Advanced Study Institute on Chaotic Dynamics : Theory and Practice

    CERN Document Server

    1992-01-01

    Many conferences, meetings, workshops, summer schools and symposia on nonlinear dynamical systems are being organized these days, dealing with a great variety of topics and themes -classical and quantum, theoretical and experimental. Some focus on integrability, or discuss the mathematical foundations of chaos. Others explore the beauty of fractals, or examine endless possibilities of applications to problems of physics, chemistry, biology and other sciences. A new scientific discipline has thus emerged, with its own distinct philosophical viewpoint and an impressive arsenal of new methods and techniques, which may be called Chaotic Dynamics. Perhaps its most outstanding achievement so far has been to shed new light on many long­ standing issues involving complicated, irregular or "chaotic" nonlinear phenomena. The concepts of randomness, complexity and unpredictability have been critically re-examined and the fundamental importance of scaling, self-similarity and sensitive dependence on parameters a...

  20. A Suggested Syllabus for the Advanced Level English Course at Gendarmerie Schools Command in Accordance with NATO STANAG 6001 Level 3 Perspective

    Science.gov (United States)

    Solak, Ekrem

    2010-01-01

    The aim of this study is to prepare a suggested syllabus in accordance with NATO Stanag 6001 Level 3 perspective for the Advanced Level English Course at Gendarmerie Schools Command which is subordinate to Gendarmerie General Command. It is believed that this study will contribute to other studies in the context of NATO Stanag 6001 language…

  1. Support for NATO Advanced Study Institute on molecular ecology of aquatic microbes, August 28--September 9, 1994. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Joint, I.

    1995-06-16

    This is a summary paper for a NATO Advanced Study Institute sponsored meeting entitled `The Molecular Ecology of Aquatic Microbes` held in Luccia, Italy from August 28 to September 9, 1994. A full reference book for the proceedings is to be published later.

  2. NATO Advanced Study Institute on Preparation and Properties of Stereoregular Polymers

    CERN Document Server

    Ciardelli, Francesco

    1980-01-01

    This book contains the texts of the main lectures presented at the NATO Advanced Studies Institute on "Advances in Preparation and Properties of Stereoregular Polymers" held at Tirrenia near Pisa, Italy, from October 3 to 14, 1978. A few contributed papers have also been included because they were concerned with topics not included in the main lectures. The primary objective of the Institute was to assist in the further development of stereoregular polymers because of the ever-increasing demand for new products with exceptional chemical and physical properties. This need has reawakened interest in the field. Indeed there is now a rapidly increasing activity in the study of stereoregular polymerization and the preparation of structurally-ordered polymers with the aim of achieving apprecia­ ble improvements in existing polymeric materials through new developments in synthesis and properties as well as in discovering new polymeric structures. In order to achieve these objectives, a broad interdiscipli­ nary co...

  3. NATO Advanced Study Institute on Ring-opening Metathesis Polymerization of Olefins and Polymerization of Alkynes

    CERN Document Server

    1998-01-01

    The first NATO Advanced Study Institute on Olefin Metathesis and Polymerization Catalysts was held on September 10-22, 1989 in Akcay, Turkey. Based on the fundamental research of RRSchrock, RGrubbs and K.B.Wagener in the field of ring opening metathesis polymerization (ROMP), acyclic diene metathesis (ADMET) and alkyne polymerization, these areas gained growing interest within the last years. Therefore the second NATO-ASI held on metathesis reactions was on Ring Opening Metathesis Po­ lymerization of Olefins and Polymerization of Alkynes on September 3-16, 1995 in Akcay, Turkey. The course joined inorganic, organic and polymer chemists to exchange their knowledge in this field. This volume contains the main and short lectures held in Akcay. To include ADMET reactions better into the title of this volume we changed it into: Metathesis Polymerization of Olefins and Alkyne Polymerization. This volume is addressed to research scientists, but also to those who start to work in the area of olefin metathesis and al...

  4. NATO Advanced Study Institute on Statistical Treatments for Estimation of Mineral and Energy Resources

    CERN Document Server

    Fabbri, A; Sinding-Larsen, R

    1988-01-01

    This volume contains the edited papers prepared by lecturers and participants of the NATO Advanced Study Institute on "Statistical Treatments for Estimation of Mineral and Energy Resources" held at II Ciocco (Lucca), Italy, June 22 - July 4, 1986. During the past twenty years, tremendous efforts have been made to acquire quantitative geoscience information from ore deposits, geochemical, geophys ical and remotely-sensed measurements. In October 1981, a two-day symposium on "Quantitative Resource Evaluation" and a three-day workshop on "Interactive Systems for Multivariate Analysis and Image Processing for Resource Evaluation" were held in Ottawa, jointly sponsored by the Geological Survey of Canada, the International Association for Mathematical Geology, and the International Geological Correlation Programme. Thirty scientists from different countries in Europe and North America were invited to form a forum for the discussion of quantitative methods for mineral and energy resource assessment. Since then, not ...

  5. NATO Advanced Study Institute on Synthetic Membranes : Science, Engineering and Applications

    CERN Document Server

    Lonsdale, H; Pinho, M

    1986-01-01

    The chapters in this book are based upon lectures given at the NATO Advanced Study Institute on Synthetic Membranes (June 26-July 8, 1983, Alcabideche, Portugal), which provided an integrated presentation of syn­ thetic membrane science and technology in three broad areas. Currently available membrane formation mechanisms are reviewed, as well as the manner in which synthesis conditions can be controlled to achieve desired membrane structures. Membrane performance in a specific separa­ tionprocess involves complex phenomena, the understanding of which re­ quires a multidisciplinary approach encompassing polymer chemistry, phys­ ical chemistry, and chemical engineering. Progress toward a global understanding of membrane phenomena is described in chapters on the principles of membrane transport. The chapters on membrane processes and applications highlight both established and emerging membrane processes, and elucidate their myriad applications. It is our hope that this book will be an enduring, comprehensi...

  6. NATO Advanced Research Workshop on Geometrical Derivatives of Energy Surfaces and Molecular Properties

    CERN Document Server

    Simons, Jack

    1986-01-01

    The development and computational implementation of analytical expres­ sions for the low-order derivatives of electronic energy surfaces and other molecular properties has undergone rapid growth in recent years. It is now fairly routine for chemists to make use of energy gradient information in locating and identifying stable geometries and transition states. The use of second analytical derivative (Hessian or curvature) expressions is not yet routine, and third and higher energy derivatives as well as property (e.g., dipole moment, polarizability) derivatives are just beginning to be applied to chemical problems. This NATO Advanced Research Workshop focused on analyzing the re­ lative merits of various strategies for deriving the requisite analyti­ cal expressions, for computing necessary integral derivatives and wave­ function parameter derivatives, and for efficiently coding these expres­ sions on conventional scalar machines and vector-oriented computers. The participant list contained many scientist...

  7. NATO Advanced Research Workshop on Exploiting Mental Imagery with Computers in Mathematics Education

    CERN Document Server

    Mason, John

    1995-01-01

    The advent of fast and sophisticated computer graphics has brought dynamic and interactive images under the control of professional mathematicians and mathematics teachers. This volume in the NATO Special Programme on Advanced Educational Technology takes a comprehensive and critical look at how the computer can support the use of visual images in mathematical problem solving. The contributions are written by researchers and teachers from a variety of disciplines including computer science, mathematics, mathematics education, psychology, and design. Some focus on the use of external visual images and others on the development of individual mental imagery. The book is the first collected volume in a research area that is developing rapidly, and the authors pose some challenging new questions.

  8. NATO Advanced Research Workshop on Incommensurate Crystals, Liquid Crystals, and Quasi-Crystals

    CERN Document Server

    Clark, N

    1988-01-01

    In this NATO-sponsored Advanced Research Workshop we succeeded in bringing together approximately forty scientists working in the three main areas of structurally incommensurate materials: incommensurate crystals (primarily ferroelectric insulators), incommensurate liquid crystals, and metallic quasi-crystals. Although these three classes of materials are quite distinct, the commonality of the physics of the origin and descrip­ tion of these incommensurate structures is striking and evident in these proceedings. A measure of the success of this conference was the degree to which interaction among the three subgroups occurred; this was facili­ tated by approximately equal amounts of theory and experiment in the papers presented. We thank the University of Colorado for providing pleasant housing and conference facilities at a modest cost, and we are especially grate­ ful to Ann Underwood, who retyped all the manuscripts into camera-ready form. J. F. Scott Boulder, Colorado N. A. Clark v CONTENTS PART I: INCO...

  9. NATO Advanced Research Workshop on Dynamics of Polyatomic Van der Waals Complexes

    CERN Document Server

    Janda, Kenneth

    1991-01-01

    This publication is the Proceedings of the NATO Advanced Research Workshop (ARW) on the Dynamics of Polyatomic Van der Waals Molecules held at the Chateau de Bonas, Castera-Verduzan, France, from August 21 through August 26, 1989. Van der Waals complexes provide important model problems for understanding energy transfer and dissipation. These processes can be described in great detail for Van der Waals complexes, and the insight gained from such studies can be applied to more complicated chemical problems that are not amenable to detailed study. The workshop concentrated on the current questions and future prospects for extend­ ing our highly detailed knowledge of triatomic Van der Waals molecule dynamics to polyatomic molecules and clusters (one molecule surrounded by several, or up to sev­ eral tens of, atoms). Both experimental and theoretical studies were discussed, with particular emphasis on the dynamical behavior of dissociation as observed in the dis­ tributions of quantum states of the dissociatio...

  10. NATO Advanced Study Institute on Microscopic Simulations of Complex Hydrodynamic Phenomena

    CERN Document Server

    Holian, Brad

    1992-01-01

    This volume contains the proceedings of a NATO Advanced Study Institute which was held in Alghero, Sardinia, in July 1991. The development of computers in the recent years has lead to the emergence of unconventional ideas aiming at solving old problems. Among these, the possibility of computing directly fluid flows from the trajectories of constituent particles has been much exploited in the last few years: lattice gases cellular automata and more generally Molecular Dynamics have been used to reproduce and study complex flows. Whether or not these methods may someday compete with more traditional approaches is a question which cannot be answered at the present time: it will depend on the new computer architectures as well as on the possibility to develop very simple models to reproduce the most complex phenomena taking place in the approach of fully developed turbulence or plastic flows. In any event, these molecular methods are already used, and sometimes in an applied engineering context, to study strong s...

  11. NATO Advanced Research Workshop on Preparedness for Nuclear and Radiological Threats

    CERN Document Server

    Diamond, David

    2015-01-01

    The nuclear crisis in Fukushima and growing threats of nuclear terrorism must serve as a wake-up call, prompting greater action to prepare ourselves for nuclear and radiological disasters. Our strategy to prepare for these threats is multi-layered and the events of these past years have proved the necessity to re-evaluate the national and international preparedness goals on a scale never before considered. The programme of NATO Advanced Research Workshop on “Preparedness for Nuclear and Radiological Threats” has been focused on science and technology challenges associated with our need to improve the national and international capacity and capability to prevent, protect against, mitigate the effects of, respond to, and recover from the nuclear and radiological disasters, including nuclear and radiological accident, terrorist attack by Improvised Nuclear Device (IND) or by “Dirty Bomb”-Radiological Dispersal Device (RDD), that pose the greatest risk to the national and international security and safety...

  12. NATO Advanced Research Workshop on Time-Dependent Quantum Molecular Dynamics : Theory and Experiment

    CERN Document Server

    Lathouwers, L

    1992-01-01

    From March 30th to April 3rd, 1992, a NATO Advanced Research workshop entitled "Time Dependent Quantum Molecular Dynamics: Theory and Experiment" was held at Snowbird, Utah. The organizing committee consisted of J. BROECKHOVE (Antwerp, Belgium), L. CEDERBAUM (Heidelberg, Germany), L. LATHOUWERS (Antwerp, Belgium), N. OHRN (Gainesville, Florida) and J. SIMONS (Salt Lake City, Utah). Fifty-two participants from eleven different countries attended the meeting at which thirty-three talks and one poster session were held. Twenty-eight participants submitted contributions to the proceedings of the meeting, which are reproduced in this volume. The workshop brought together experts in different areas 0 f molecular quantum dynamics, all adhering to the time dependent approach. The aim was to discuss and compare methods and applications. The ~amiliarityo~ the aUdience with the concepts o~ time dependent approaches greatly facilitated topical discussions and probing towards new applications. A broad area of subject matt...

  13. NATO Advanced Research Workshop on Ionization of Solids by Heavy Particles

    CERN Document Server

    1993-01-01

    This book collects the papers presented at the NATO Advanced Research Workshop on "Ionization of Solids by Heavy Particles", held in Giardini-Naxos (Taormina), Italy, on June 1 -5, 1992. The meeting was the first to gather scientists to discuss the physics of electron emission and other ionization effects occurring during the interaction of heavy particles with condensed matter. The central problem in the field is how to use observations of electron emission and final radiation damage to understand what happens inside the solid, like excitation mechanisms, the propagation of the electronic excitation along different pathways, and surface effects. The ARW began with a brief survey of the field, stressing the unknowns. It was pointed out that ionization theories can only address the very particular case of weak perturbations. For this problem, this meant high speed, low-charged projectiles (a perturbation treatment of interactions with slow, highly charged ions was later presented). Only semi-empirical ...

  14. NATO Advanced Research Workshop on The Biogeochemical Cycling of Sulfur and Nitrogen in the Remote Atmosphere

    CERN Document Server

    Charlson, Robert; Andreae, Meinrat; Rodhe, Henning

    1985-01-01

    Viewed from space, the Earth appears as a globe without a beginning or an end. Encompassing the globe is the atmosphere with its three phases-­ gaseous, liquid, and solid--moving in directions influenced by sunlight, gravity, and rotation. The chemical compositions of these phases are determined by biogeochemical cycles. Over the past hundred years, the processes governing the rates and reactions in the atmospheric biogeochemical cycles have typically been studied in regions where scientists lived. Hence, as time has gone by, the advances in our knowledge of atmospheric chemical cycles in remote areas have lagged substantially behind those for more populated areas. Not only are the data less abundant, they are also scattered. Therefore, we felt a workshop would be an excellent mechanism to assess the state­ of-knowledge of the atmospheric cycles of sulfur and nitrogen in remote areas and to make recommendations for future research. Thus, a NATO Advanced Research Workshop '~he Biogeochemical Cycling of Sulfu...

  15. NATO Advanced Research Workshop on Earth Rotation : Solved and Unsolved Problems

    CERN Document Server

    1986-01-01

    The idea for organl.zl.ng an Advanced Research Workshop entirely devoted to the Earth rotation was born in 1983 when Professor Raymond Hide suggested this topic to the special NATO panel of global transport mechanism in the Geosciences. Such a specialized meeting did not take place since the GEOP research conference on the rotation of the Earth and polar motion which was held at the Ohio State University (USA) in 1973. In the last ten years, highly precise measurements of the Earth's rotation parameters and new global geophysical data have become available allowing major advance to be made in the under­ standing of the various irregularities affecting the Earth's rotation. The aim of the workshop was to bring together scientists who have made important contributions in this field during the last decade both at the observational and geophysical interpretation levels. The confe­ rence was divided into four main topics. The first session was dedicated to the definition, implementation and maintenance of the te...

  16. NATO Advanced Research Workshop on Thin Film Growth Techniques for Low-Dimensional Structures

    CERN Document Server

    Parkin, S; Dobson, P; Neave, J; Arrott, A

    1987-01-01

    This work represents the account of a NATO Advanced Research Workshop on "Thin Film Growth Techniques for Low Dimensional Structures", held at the University of Sussex, Brighton, England from 15-19 Sept. 1986. The objective of the workshop was to review the problems of the growth and characterisation of thin semiconductor and metal layers. Recent advances in deposition techniques have made it possible to design new material which is based on ultra-thin layers and this is now posing challenges for scientists, technologists and engineers in the assessment and utilisation of such new material. Molecular beam epitaxy (MBE) has become well established as a method for growing thin single crystal layers of semiconductors. Until recently, MBE was confined to the growth of III-V compounds and alloys, but now it is being used for group IV semiconductors and II-VI compounds. Examples of such work are given in this volume. MBE has one major advantage over other crystal growth techniques in that the structure of the growi...

  17. NATO Advanced Study Institute on Instabilities and Chaos in Quantum Optics

    CERN Document Server

    Arecchi, F; Lugiato, L; Instabilities and Chaos in Quantum Optics II

    1988-01-01

    This volume contains tutorial papers from the lectures and seminars presented at the NATO Advanced Study Institute on "Instabilities and Chaos in Quantum Optics", held at the "Il Ciocco" Conference Center, Castelvecchio Pascoli, Lucca, Italy, June 28-July 7, 1987. The title of the volume is designated Instabilities and Chaos in Quantum Optics II, because of the nearly coincident publication of a collection of articles on research in this field edited by F.T. Arecchi and R.G. Harrison [Instabilities and Chaos in Quantum Optics, (Springer, Berlin, 1987) 1. That volume provides more detailed information about some of these topics. Together they will serve as a comprehensive and tutorial pair of companion volumes. This school was directed by Prof. Massimo Inguscio, of the Department of Physics, University of Naples, Naples, Italy to whom we express our gratitude on behalf of all lecturers and students. The Scientific Advisory Committee consisted of N.B. Abraham of Bryn Mawr College; F.T. Arecchi of the National I...

  18. NATO Advanced Study Institute on Laser Interactions with Atoms, Solids,and Plasmas

    CERN Document Server

    1994-01-01

    The aim of this NATO Advanced Study Institute was to bring together scientists and students working in the field of laser matter interactions in order to review and stimulate developmentoffundamental science with ultra-short pulse lasers. New techniques of pulse compression and colliding-pulse mode-locking have made possible the construction of lasers with pulse lengths in the femtosecond range. Such lasers are now in operation at several research laboratories in Europe and the United States. These laser facilities present a new and exciting research direction with both pure and applied science components. In this ASI the emphasis is on fundamental processes occurring in the interaction of short laser pulses with atoms, molecules, solids, and plasmas. In the case of laser-atom (molecule) interactions, high power lasers provide the first access to extreme high-intensity conditions above 10'8 Watts/em', a new frontier for nonlinear interaction of photons with atoms and molecules. New phenomena observed include ...

  19. NATO Advanced Research Workshop on Painlevé Transcendents, their Asymptotics and Physical Applications

    CERN Document Server

    Winternitz, Pavel; Painlevé Transcendents, their Asymptotics and Physical Applications

    1992-01-01

    The NATO Advanced Research Workshop "Painleve Transcendents, their Asymp­ totics and Physical Applications", held at the Alpine Inn in Sainte-Adele, near Montreal, September 2 -7, 1990, brought together a group of experts to discuss the topic and produce this volume. There were 41 participants from 14 countries and 27 lectures were presented, all included in this volume. The speakers presented reviews of topics to which they themselves have made important contributions and also re­ sults of new original research. The result is a volume which, though multiauthored, has the character of a monograph on a single topic. This is the theory of nonlinear ordinary differential equations, the solutions of which have no movable singularities, other than poles, and the extension of this theory to partial differential equations. For short we shall call such systems "equations with the Painleve property". The search for such equations was a very topical mathematical problem in the 19th century. Early work concent...

  20. NATO Advanced Research Workshop on Squeezed and Non-classical Light

    CERN Document Server

    Pike, E; Squeezed and Non-classical Light

    1988-01-01

    The recent generation in the laboratory of phase squeezed and intensity squeezed light beams has brought to fruition the theoretical predictions of such non-classical phenomena which have been made and developed in recent years by a number of workers in the field of quantum optics. A vigorous development is now underway of both theory and experiment and the first measurements have been coi:Jfirmed and extended already in some half dozen laboratories. Although the fields of application of these novellight sources are as yet somewhat hazy in our minds and some inspired thinking is required along these lines, the pace and excitement of the research is very clear. It is to he hoped that the new possibilities of: making measurements below the quantum shot noise lirnit which is made possible by these squeezed states of light willlead to further fundamental advances in the near future. In this NATO ARW a number of the leaders in the field met in the extremely pleasant surroundings of Cortina d'Ampezzo and th...

  1. NATO Advanced Research Workshop on Methods and Mechanisms for Producing Ions from Large Molecules

    CERN Document Server

    Ens, Werner

    1991-01-01

    A NATO Advanced Research Workshop on Methods and Mechanisms for Producing Ions from Large Molecules was held at Minaki Lodge, Minaki, Ontario, Canada, from 24 to 28 June 1990. The workshop was hosted by the time-of-flight group of the Department of Physics at the University of Manitoba, and was attended by 64 invited participants from around the world. Twenty-nine invited talks were given and 19 papers were presented as posters. Of the 48 contributions, 38 are included in these proceedings. The conference was organized to study the rapidly changing field of mass spectrometry of biomolecules. Particle-induced desorption (especially with MeV particles) has been the most effective method of producing molecular ions from biomolecules. An important part of the workshop was devoted to recent developments in this field, particularly to progress in understanding the fundamentals of the desorption process. In this respect, the meeting was similar to previous conferences in Marburg, FRG (1978); Paris, F (1980); Uppsala...

  2. NATO Advanced Research Workshop on The Morphology and Dynamics of the Polar Cusp

    CERN Document Server

    Egeland, Alv

    1985-01-01

    These proceedings are based upon introductory talks, research reports and discussions from the NATO Advanced Workshop on the "Morphology and Dynamics of the Polar Cusp", held at Lillehammer, Norway, 7-12 May, 1984. The upper atmosphere at high latitudes is called the "Earth's win­ dow to outer space". Through various electrodynamic coupling process­ es as well as through direct transfer of particles many geophysical effects displayed there are direct manifestations of phenomena occurring in the deep space. The high latitude ionosphere will also exert a feedback on the regions of the magnetosphere and atmosphere to which it is coupled, acting as a momentum and energy source and sink, and a source of particles. Of particular interest are the sections of the near space known as the Polar Cusp. A vast portion of the earth's magnetic field envelope is electrically connected to these regions. This geometry results in a spatial mapping of the magnetospheric pro­ cesses and a focusing on to the ionosphere. In the ...

  3. NATO Advanced Study Institute on Lower-Dimensional Systems and Molecular Electronics

    CERN Document Server

    Day, Peter; Papavassiliou, George

    1990-01-01

    This volume represents the written account of the NATO Advanced Study Institute "Lower-Dimensional Systems and Molecular Electronics" held at Hotel Spetses, Spetses Island, Greece from 12 June to 23 June 1989. The goal of the Institute was to demonstrate the breadth of chemical and physical knowledge that has been acquired in the last 20 years in inorganic and organic crystals, polymers, and thin films, which exhibit phenomena of reduced dimensionality. The interest in these systems started in the late 1960's with lower-dimensional inorganic conductors, in the early 1970's with quasi-one-dimensional crystalline organic conductors. which by 1979 led to the first organic superconductors, and, in 1977, to the fITSt conducting polymers. The study of monolayer films (Langmuir-Blodgett films) had progressed since the 1930's, but reached a great upsurge in . the early 1980's. The pursuit of non-linear optical phenomena became increasingly popular in the early 1980's, as the attention turned from inorganic crystals t...

  4. NATO Advanced Research Workshop on The Design of Mathematical Modelling Courses for Engineering Education

    CERN Document Server

    Moscardini, Alfredo

    1994-01-01

    As the role of the modern engineer is markedly different from that of even a decade ago, the theme of engineering mathematics educa­ tion (EME) is an important one. The need for mathematical model­ ling (MM) courses and consideration of the educational impact of computer-based technology environments merit special attention. This book contains the proceeding of the NATO Advanced Research Workshop held on this theme in July 1993. We have left the industrial age behind and have entered the in­ formation age. Computers and other emerging technologies are penetrating society in depth and gaining a strong influence in de­ termining how in future society will be organised, while the rapid change of information requires a more qualified work force. This work force is vital to high technology and economic competitive­ ness in many industrialised countries throughout the world. Within this framework, the quality of EME has become an issue. It is expected that the content of mathematics courses taught in schools o...

  5. NATO Advanced Research Workshop on Chemical Instabilities : Applications in Chemistry, Engineering, Geology, and Materials Science

    CERN Document Server

    Baras, F

    1984-01-01

    On March 14-18, 1983 a workshop on "Chemical Instabilities: Applications in Chemistry, Engineering, Geology, and Materials Science" was held in Austin, Texas, U.S.A. It was organized jointly by the University of Texas at Austin and the Universite Libre de Bruxelles and sponsored qy NATO, NSF, the University of Texas at Austin, the International Solvay Institutes and the Ex­ xon Corporation. The present Volume includes most of the material of the in­ vited lectures delivered in the workshop as well as material from some posters, whose content was directly related to the themes of the invited lectures. In ,recent years, problems related to the stability and the nonlinear dynamics of nonequilibrium systems invaded a great num­ ber of fields ranging from abstract mathematics to biology. One of the most striking aspects of this development is that subjects reputed to be "classical" and "well-established" like chemistry, turned out to give rise to a rich variety of phenomena leading to multiple steady states and...

  6. NATO Enlargement.

    Science.gov (United States)

    Volker, Karen

    1998-01-01

    Reviews the history of the North Atlantic Treaty Organization (NATO) and describes the debate over expanding its membership. Includes a discussion of the process for adding NATO members and a copy of the treaty. Suggests several exercises to help students better understand the NATO-expansion debate. (DSK)

  7. NATO Advanced Research Workshop on Vectorization of Advanced Methods for Molecular Electronic Structure

    CERN Document Server

    1984-01-01

    That there have been remarkable advances in the field of molecular electronic structure during the last decade is clear not only to those working in the field but also to anyone else who has used quantum chemical results to guide their own investiga­ tions. The progress in calculating the electronic structures of molecules has occurred through the truly ingenious theoretical and methodological developments that have made computationally tractable the underlying physics of electron distributions around a collection of nuclei. At the same time there has been consider­ able benefit from the great advances in computer technology. The growing sophistication, declining costs and increasing accessibi­ lity of computers have let theorists apply their methods to prob­ lems in virtually all areas of molecular science. Consequently, each year witnesses calculations on larger molecules than in the year before and calculations with greater accuracy and more com­ plete information on molecular properties. We can surel...

  8. Threshold(trade mark) Immunoassays for Identification of Biological Agents: NATO SIBCA Exercise III

    Science.gov (United States)

    2002-12-01

    le sous-groupe VII de NATO tchanti11onnage et identification des agents biologiques et chimiques (SIBCA) a conduit le troisi~me exercice de...biotest Threshold~m, un biotest avec capteur potentiom~trique adressable de lumi~re (LAPS). Le biotest Threshold~m d’antig~ne de capture 6tait...identification des agents biologiques et chimiques (SIBCA) a organis6 plusieurs exercices internationaux de formation durant lesquels chaque nation participante

  9. Advances in Norovirus Biology

    OpenAIRE

    Karst, Stephanie M.; Wobus, Christiane E.; Ian G Goodfellow; Green, Kim Y.; Virgin, Herbert W.

    2014-01-01

    Human noroviruses are a major cause of epidemic and sporadic gastroenteritis worldwide, and can chronically infect immunocompromised patients. Efforts to develop effective vaccines and antivirals have been hindered by the uncultivable nature and extreme genetic diversity of human noroviruses. Although they remain a particularly challenging pathogen to study, recent advances in norovirus animal models and in vitro cultivation systems have led to an increased understanding of norovirus molecula...

  10. NATO Advanced Study Institute on Advances in the Computer Simulations of Liquid Crystals

    CERN Document Server

    Zannoni, Claudio

    2000-01-01

    Computer simulations provide an essential set of tools for understanding the macroscopic properties of liquid crystals and of their phase transitions in terms of molecular models. While simulations of liquid crystals are based on the same general Monte Carlo and molecular dynamics techniques as are used for other fluids, they present a number of specific problems and peculiarities connected to the intrinsic properties of these mesophases. The field of computer simulations of anisotropic fluids is interdisciplinary and is evolving very rapidly. The present volume covers a variety of techniques and model systems, from lattices to hard particle and Gay-Berne to atomistic, for thermotropics, lyotropics, and some biologically interesting liquid crystals. Contributions are written by an excellent panel of international lecturers and provides a timely account of the techniques and problems in the field.

  11. NATO Advanced Study Institute on Magnetic Resonance : Introduction, Advanced Topics and Applications to Fossil Energy

    CERN Document Server

    Fraissard, Jacques

    1984-01-01

    This volume contains the lectures presented at an Advanced Study Institute on "Magnetic Resonance Techniques in Fossil Energy Problems," which was held at the village of Maleme, Crete, in July of 1983. As of this writing, a different popular attitude prevails from that when the ASI was proposed as far as how critical the world energy picture is. In the popular press, a panglossian attitude (the "petroleum glut" of the 80's) has replaced the jeremiads of the 70's ( a catastrophic "energy crisis"). Yet, there are certain important constants: (a) for the foreseeable future, fossil energy sources (petroleum, coal, oil shale, etc. ) will continue to be of paramount importance; and (b) science and technology of the highest order are needed to extend the fossil ener~y resource base and to utilize it in a cost-effective manner that is also environmentally acceptable. It is precisely this second item that this volume addresses. The volume introduces the phenomenology of magnetic resonance ~n a unified and detailed man...

  12. NATO Advanced Study Institute International Advanced Course on The Liquid State and Its Electrical Properties

    CERN Document Server

    Christophorou, L; Luessen, L

    1988-01-01

    As the various disciplines of science advance, they proliferate and tend to become more esoteric. Barriers of specialized terminologies form, which cause scientists to lose contact with their colleagues, and differences in points-of-view emerge which hinder the unification of knowledge among the various disciplines, and even within a given discipline. As a result, the scientist, and especially the student, is in many instances offered fragmented glimpses of subjects that are funda­ mentally synthetic and that should be treated in their own right. Such seems to be the case of the liquid state. Unlike the other states of matter -- gases, solids, and plasmas -- the liquid state has not yet received unified treatment, probably because it has been the least explored and remains the least understood state of matter. Occasionally, events occur which help remove some of the barriers that separate scientists and disciplines alike. Such an event was the ASI on The Liquid State held this past July at the lovely Hotel T...

  13. NATO Advanced Research Workshop on Approximation by Solutions of Partial Differential Equations, Quadrature Formulae, and Related Topics

    CERN Document Server

    Goldstein, M; Haussmann, W; Hayman, W; Rogge, L

    1992-01-01

    This volume consists of the proceedings of the NATO Advanced Research Workshop on Approximation by Solutions of Partial Differential Equations, Quadrature Formulae, and Related Topics, which was held at Hanstholm, Denmark. These proceedings include the main invited talks and contributed papers given during the workshop. The aim of these lectures was to present a selection of results of the latest research in the field. In addition to covering topics in approximation by solutions of partial differential equations and quadrature formulae, this volume is also concerned with related areas, such as Gaussian quadratures, the Pompelu problem, rational approximation to the Fresnel integral, boundary correspondence of univalent harmonic mappings, the application of the Hilbert transform in two dimensional aerodynamics, finely open sets in the limit set of a finitely generated Kleinian group, scattering theory, harmonic and maximal measures for rational functions and the solution of the classical Dirichlet problem. In ...

  14. NATO Advanced Research Workshop on Applications of Picosecond Spectroscopy to Chemistry

    CERN Document Server

    1984-01-01

    With the development of lasers that can generate light 11 14 pulses ranging from 10- - 10- sec duration, and capable of 13 peak powers in excess of 10 watts scientists have been able to investigate the interactions of light with matter in a time and power domain not previously possible. These ultrashort laser pulses provide a powerful tool for the study of chemical phenomena at the most fundamental level. Many of the elementary processes of importance in chemistry including energy dissipa­ tion, molecular motions, structural and chemical changes occur on a very short time scale and thus require special approaches. Th~ use of ultrashort laser pulses to perturb and to probe systems of interest affords a direct approach to the time reso­ lution of very rapid chemical phenomena. It was recognition of the impact of these relatively new approaches to chemical phenomena that motivated NATO to sponsor a meeting on the applications of picosecond spectroscopy in chemistry. The primary aim of the NATO workshop was to ...

  15. NATO Advanced Study Institute on Structural Theory of Automata, Semigroups and Universal Algebra

    CERN Document Server

    Rosenberg, Ivo; Goldstein, Martin

    2005-01-01

    Several of the contributions to this volume bring forward many mutually beneficial interactions and connections between the three domains of the title. Developing them was the main purpose of the NATO ASI summerschool held in Montreal in 2003. Although some connections, for example between semigroups and automata, were known for a long time, developing them and surveying them in one volume is novel and hopefully stimulating for the future. Another aspect is the emphasis on the structural theory of automata that studies ways to contstruct big automata from small ones. The volume also has contributions on top current research or surveys in the three domains. One contribution even links clones of universal algebra with the computational complexity of computer science. Three contributions introduce the reader to research in the former East block.

  16. NATO Advanced Research Workshop on Optical Switching in Low-Dimensional Systems

    CERN Document Server

    Bányai, L

    1989-01-01

    This book contains all the papers presented at the NATO workshop on "Optical Switching in Low Dimensional Systems" held in Marbella, Spain from October 6th to 8th, 1988. Optical switching is a basic function for optical data processing, which is of technological interest because of its potential parallelism and its potential speed. Semiconductors which exhibit resonance enhanced optical nonlinearities in the frequency range close to the band edge are the most intensively studied materials for optical bistability and fast gate operation. Modern crystal growth techniques, particularly molecular beam epitaxy, allow the manufacture of semiconductor microstructures such as quantum wells, quantum wires and quantum dots in which the electrons are only free to move in two, one or zero dimensions, of the optically excited electron-hole pairs in these low respectively. The spatial confinement dimensional structures gives rise to an enhancement of the excitonic nonlinearities. Furthermore, the variations of the microstr...

  17. NATO Advanced Study Institute on Hydrogen in Disordered and Amorphous Solids

    CERN Document Server

    Bowman, Robert

    1986-01-01

    This is the second volume in the NATO ASI series dealing with the topic of hydrogen in solids. The first (V. B76, Metal Hydrides) appeared five years ago and focussed primarily on crystalline phases of hydrided metallic systems. In the intervening period, the amorphous solid state has become an area of intense research activity, encompassing both metallic and non-metallic, e.g. semiconducting, systems. At the same time the problem of storage of hydrogen, which motivated the first ASI, continues to be important. In the case of metallic systems, there were early indications that metallic glasses and disordered alloys may be more corrosion resistant, less susceptible to embrittlement by hydrogen and have a higher hydrogen mobility than ordered metals or intermetallics. All of these properties are desirable for hydrogen storage. Subsequent research has shown that thermodynamic instability is a severe problem in many amorphous metal hydrides. The present ASI has provided an appropriate forum to focus on these issu...

  18. NATO Advanced Research Workshop on Emergency Management after a Major Terror Attack : the New Challenges for First Responders and Civil Protection

    CERN Document Server

    Steinhäusler, Friedrich

    2007-01-01

    International terrorism remains a significant threat to the peace of the world. Weapons using various materials and delivery systems have been directed against cities and infrastructure, and other materials are postulated to be usable within the near future. Some of these materials are unusual or exotic, while some are modifications of materials used daily for other purposes: biological, chemical, radiological, nuclear and explosive. These materials pose a safety challenge for first responders, slowing the response and potentially killing scarce trained personnel. This book provides information about how leading agencies across the NATO membership are preparing to confront and respond to terrorists deploying Weapons of Mass Destruction (WMD), Weapons of Mass Killing (WMK) and Weapons of Mass Disruption (WMDi). Based on contributions by experts from NATO member states, Israel and the Russian Federation, this book offers information on fourth generation warfare as a new challenge to first responders. It also pr...

  19. NATO Handbook.

    Science.gov (United States)

    North Atlantic Treaty Organization, Brussels (Belgium). Information Service.

    This booklet outlines the aims and activities of the North Atlantic Treaty Organization (NATO) and describes the structure of the organization. It is presented in five sections. Section one presents the text of the treaty, which was ratified in 1949. Section two briefly analyzes the most significant articles in the treaty. In general, the treaty…

  20. Synthetic biology: advancing biological frontiers by building synthetic systems

    OpenAIRE

    Chen, Yvonne Yu-Hsuan; Galloway, Kate E; Smolke, Christina D.

    2012-01-01

    Advances in synthetic biology are contributing to diverse research areas, from basic biology to biomanufacturing and disease therapy. We discuss the theoretical foundation, applications, and potential of this emerging field.

  1. NATO SOF Transformation and the development of NATO SOF medical doctrine and policy.

    Science.gov (United States)

    Wallace, G Rhett

    2009-01-01

    The North Atlantic Treaty Organization (NATO) Special Operations Forces (SOF) Coordination Center (NSCC) is a new NATO memorandum of understanding (MOU) organization that is effecting rapid advancement in NATO's ability to efficiently utilize SOF at the strategic/operational level. The NSCC's lines of development in communications information systems (CIS), education, training, and real life support to the International Security Assistance Force (ISAF) SOF and the development of pivotal documents to develop and mature NATO SOF doctrine and policy are all occurring at lightning speed. Within this process of establishing a SOF community in NATO, the author's focus is the development of previously non-existent NATO SOF medical doctrine and policy. Many barriers to change lie ahead, but through unity of effort, we will ensure certainty of our actions.

  2. NATO Advanced Study Institute on Magnetic Nanostructures for Micro-Electromechanical Systems and Spintronic Applications

    CERN Document Server

    Azzerboni, Bruno; Pareti, Luigi; Ghidini, Massimo

    2007-01-01

    Proposes a synergic junction between the characteristic expertise of the engineering and the knowledge of the basic scienceThe main effect should be a cross-cultural fertilization favoring an interdisciplinary enrichment for the readers and their research perspectivesCovers the most advanced fields of modern magnetic nano-technologiesA unique source of up to date information for the young physicist, chemist or engineer as well as a crucial reference for the expert scientist and the teacher of advanced university coursesDeals with the most important topics in the field of modern magnetism in fu

  3. Meie NATO / Kristiina Ojuland

    Index Scriptorium Estoniae

    Ojuland, Kristiina, 1966-

    2004-01-01

    NATO on pärast alliansi-siseseid pingeid edasi arenenud, ta on võtnud üle Afganistani operatsiooni, räägitakse ka NATO-le suurema rolli andmisest stabiilsuse tagamisel Iraagis. Välisministri sõnul on tähtsaim alus NATO elujõule transatlantiliste suhete vastupidavus. Eesti rollist NATO liikmena. Vt. samas: NATO sõjaline juhtimisstruktuur

  4. NATO Advanced Research Wokshop “Recent Trends in Energy Security: With Special Emphasis on Low-Dimensional Functional Materials”

    CERN Document Server

    Matrasulov, Davron; Rakhimov, Khamdam; Low-Dimensional F unctional Materials

    2013-01-01

    Maintaining and improving energy security is one of the biggest challenges worldwide.  The NATO ARW conference in Tashkent, October 2012, was devoted to discussing visions and concepts that are currently discussed in different research fields. Leading scientists have written concise contributions to introduce the reader to this exciting topic.  The present volume summarizes the discussions at the conference.

  5. NATO Advanced Research Workshop on Chemosensors of Ion and Molecule Recognition

    CERN Document Server

    Czarnik, A

    1997-01-01

    In the broad field of supramolecular chemistry, the design and hence the use of chemosensors for ion and molecule recognition have developed at an extroardinary rate. This imaginative and creative area which involves the interface of different disciplines, e.g. organic and inorganic chemistry, physical chemistry, biology, medicine, environmental science, is not only fundamental in nature. It is also clear that progress is most rewarding for several new sensor applications deriving from the specific signal delivered by the analyte-probe interaction. Indeed, if calcium sensing in real time for biological purposes is actually possible, owing to the emergence of efficient fluorescent receptors, other elements can also be specifically detected, identified and finally titrated using tailored chemosensors. Pollutants such as heavy metals or radionuclides are among the main targets since their detection and removal could be envisioned at very low concentrations with, in addition, sensors displaying specific and stron...

  6. NATO Advanced Study Institute on Improved Methods for Examining the Submicron World

    CERN Document Server

    McGowan, J; Shinozaki, Douglas

    1986-01-01

    An Institute like ours cannot help but lend credence to the notion of the late Derek J. de Solla Price of Yale University that "the scientific revolution was largely the improvement, invention and use of a series of instruments . . . . that expanded the reach of science in innumerable directions". Most of science today and in years gone by depends on the experimental observation of struc­ ture on the small scale with microscopes, and on the large scale with telescopes. The first instruments to expand the observational range of the human eye were simple optical systems, designed in the case of microscopes and telescopes to magnify the image. The big breakthrough in the 17th century was not when Galileo first turned his telescope to the heavens, but when improvements in lens-grinding techniques allowed eyeglass makers to make the first telescope. Early microscopy revealed new and previously unsuspected microstruc­ tures in biological and non-biological materials and thus helped to enlarge on the understanding...

  7. NATO Advanced Research Workshop on The Theory of Chemical Reaction Dynamics

    CERN Document Server

    1986-01-01

    The calculation of cross sections and rate constants for chemical reactions in the gas phase has long been a major problem in theoretical chemistry. The need for reliable and applicable theories in this field is evident when one considers the significant recent advances that have been made in developing experimental techniques, such as lasers and molecular beams, to probe the microscopic details of chemical reactions. For example, it is now becoming possible to measure cross sections for chemical reactions state selected in the vibrational­ rotational states of both reactants and products. Furthermore, in areas such as atmospheric, combustion and interstellar chemistry, there is an urgent need for reliable reaction rate constant data over a range of temperatures, and this information is often difficult to obtain in experiments. The classical trajectory method can be applied routinely to simple reactions, but this approach neglects important quantum mechanical effects such as tunnelling and resonances. For al...

  8. NATO Advanced Study Institute and International School of Materials Science and Technology

    CERN Document Server

    Balkanski, Minko; 15th Course on Solid State Microbatteries

    1990-01-01

    This Advanced Study Institute on the topic of SOLID STATE MICROBATTERIES is the third and final institute on the general theme of a field of study now termed "SOLID STATE IONICS". The institute was held in Erice, Sicily, Italy, 3 - 15 July 1988. The objective was to assemble in one location individuals from industry and academia expert in the fields of microelectronics and solid state ionics to determine the feasibility of merging a solid state microbattery with microelectronic memory. Solid electrolytes are in principle amenable to vapor deposition, RF or DC sputtering, and other techniques used to fabricate microelectronic components. A solid state microbattery 1 1 mated on the same chip carrier as the chip can provide on board memory backup power. A solid state microbattery assembled from properly selected anode/solid electrolyte/cathode materials could have environmental endurance properties equal or superior to semiconductor memory chips. Lectures covering microelectronics, present state-of-art solid sta...

  9. NATO Advanced Research Workshop “Nuclear Power and Energy Security”

    CERN Document Server

    Apikyan, Samuel A; Nuclear Power and Energy Security

    2010-01-01

    World energy consumption has grown dramatically over the past few decades. This growth in energy demand will be driven by large increases in both economic growth and world population coupled with rising living standards in rapidly growing countries. The last years, we routinely hear about a "renaissance" of nuclear energy. The recognition that nuclear power is vital to global energy security in the 21st century has been growing for some time. "The more we look to the future, the more we can expect countries to be considering the potential benefits that expanding nuclear power has to offer for the global environment and for economic growth," IAEA Director General Mohamed ElBaradei said in advance of a gathering of 500 nuclear power experts assembled in Moscow for the "International Conference on Fifty Years of Nuclear Power - the Next Fifty Years". But such a renaissance is not a single-valued and sure thing. Legitimate four unresolved questions remain about high relative costs; perceived adverse safety, envir...

  10. NATO Advanced Study Institute on Chemical Crystallography with Pulsed Neutrons and Synchrotron X-Rays

    CERN Document Server

    Jeffrey, George

    1988-01-01

    X-ray and neutron crystallography have played an increasingly impor­ tant role in the chemical and biochemical sciences over the past fifty years. The principal obstacles in this methodology, the phase problem and com­ puting, have been overcome. The former by the methods developed in the 1960's and just recognised by the 1985 Chemistry Nobel Prize award to Karle and Hauptman, the latter by the dramatic advances that have taken place in computer technology in the past twenty years. Within the last decade, two new radiation sources have been added to the crystallographer's tools. One is synchrotron X-rays and the other is spallation neutrons. Both have much more powerful fluxes than the pre­ vious sources and they are pulsed rather than continuos. New techniques are necessary to fully exploit the intense continuos radiation spectrum and its pulsed property. Both radiations are only available from particular National Laboratories on a guest-user basis for scientists outside these Na­ tional Laboratories. Hi...

  11. NATO Conference

    CERN Document Server

    Lynn, W

    1975-01-01

    The contents of this volume involve selection, emendation and up-dating of papers presented at the NATO Conference "Mathe­ matical Analysis of Decision problems in Ecology" in Istanbul, Turkey, July 9-13, 1973. It was sponsored by the System Sciences Division of NATO directed by Dr. B. Bayraktar with local arrange­ ments administered by Dr. Ilhami Karayalcin, professor of the Department of Industrial Engineering at the Technical University of Istanbul. It was organized by A. Charnes, University professor across the University of Texas System, and Walter R.Lynn, Di­ rector of the School of Civil and Environmental Engineering at Cornell Unjversity. The objective of the conference was to bring together a group of leading researchers from the major sciences involved in eco­ logical problems and to present the current state of progress in research of a mathematical nature which might assist in the solu­ tion of these problems. Although their presentations are not herein recorded, the key­ note address of Dr....

  12. NATO Advanced Study Institute

    CERN Document Server

    Quantum electrodynamics and quantum optics

    1984-01-01

    The borderline of quantum electrodynamics and quantum optics offer spectacular results and problems concerning the foundations of radiation theory. Perhaps the major new viewpoint that has emerged from recent investigations is that one can now work inside a time-dependent quantum process, whereas up to now all elementary quantum processes were either stationary, or one worked with asymptotic in-and out-states, i.e. an S-matrix approach. In the-rirst part of this volume, the Quantum Electrodynamics, the present status of the main approaches to this most accurate of all physical theories are discussed: the Hamiltonian approach, the Green's function approach with particular emphasis to bound state problems, and the newer, nonperturbative approach. The latest numerical results on radiative corrections, Lamb shifts and anomalous magnetic moments are reviewed with new results for high Z atoms. Also discussed are different theoretical interpretations of the radiative phenomena as due to quantized field vacuu...

  13. Atlas of NATO.

    Science.gov (United States)

    Young, Harry F.

    This atlas provides basic information about the North Atlantic Treaty Organization (NATO). Formed in response to growing concern for the security of Western Europe after World War II, NATO is a vehicle for Western efforts to reduce East-West tensions and the level of armaments. NATO promotes political and economic collaboration as well as military…

  14. NATO Advanced Study Institute on Engineering of Crystalline Materials Properties : State of the Art in Modeling Design and Applications. New Materials for better Defence and Security

    CERN Document Server

    Braga, Dario; Addadi, Lia

    2008-01-01

    This volume collects the lecture notes (ordered alphabetically according to the first author surname) of the talks delivered by the main speakers at the Erice 2007 International School of Crystallography, generously selected by NATO as an Advanced Study Institute (# 982582). The aim of the school was to discuss the state-of-the-art in molecular materials design, that is, the rational analysis and fabrication of crystalline solids showing a predefined structural organization of their component molecules and ions, which results in the manifestation of a specific collective property of technological interest. The School was held on June 7–17, 2007, in Erice (an old town, over 3000 years, located on the top of a Sicilian hill that oversees the sea near Trapani). The school developed following two parallel lines. First we established “where we are” in terms of modelling, design, synthesis and applications of crystalline solids with predefined properties. Second, we attempted to define current and possible fu...

  15. Ilves lendas NATO peakorterisse

    Index Scriptorium Estoniae

    2008-01-01

    President Toomas Hendrik Ilves lendas Brüsselisse kohtuma NATO tippametnike ja sõjaväelastega. Eesti riigipea kohtub NATO peasekretäri Jaap de Hoop Schefferiga, esineb Põhja-Atlandi Nõukogu (NAC) ees, külastab NATO sõjalist peakorterit Euroopas (SHAPE) ja kohtub seal liitlasvägede kõrgeima sõjalise juhiga Euroopas, kindral John Craddockiga. Vabariigi President töövisiidil Brüsselis 3.-5.02.2008

  16. Acupuncture and NATO

    Science.gov (United States)

    2011-01-01

    MILITARY ACUPUNCTURE OUTSIDE THE UNITED STATES Acupuncture and NATO Jean-Louis Belard, MD, Ret French Army Col,1 and Arnyce R. Pock, MD, Col, USAF...describes an opportunity by which acupuncture could be utilized as part of the initial military medical response to a cataclysmic disaster. Key Words... Acupuncture , NATO INTRODUCTION The North Atlantic Treaty Organization (NATO)was established in April 1949 as an intergovern- mental alliance aimed

  17. NATO Advanced Research Workshop on Environmental and Biological Risks of Hybrid Organic-Silicon Nanodevices

    CERN Document Server

    Kozyrev, Sergey; Vaseashta, Ashok

    2009-01-01

    Even though there is no generally accepted definition of nanotechnologies to be defined as distinct discipline there is an emerging consensus that their advent and development is a growing in importance factor of the contemporary and future technological civilization. One of these most fundamental issues we are confronted with is the compatibility with life itself. From single cell organisms to humans, carbon is a key building block of all molecular structures of life. In contrast the man created electronic industry to build on other elements, of which silicon is the most common. Both carbon and silicon create molecular chains, although different in their internal structure. All life is built from carbon-based chains. As long as the man built technological products do not directly interfere with the physiology of life the associated risks from them are relatively easy to identify. They are primarily in the environmental pollution and the possibility of upsetting the natural balance of biocoenosis, on a planet...

  18. NATO tippkohtumine Bukarestis

    Index Scriptorium Estoniae

    2008-01-01

    1.-3. aprillil Bukarestis toimunud NATO 20. tippkohtumisel osales ka Eesti delegatsioon eesotsas president Toomas Hendrik Ilvesega. Eesti riigipea esines sõnavõtuga tippkohtumisega paralleelselt toimunud NATO temaatikaga tegelevate noorteorganisatsioonide esindajate (Young Atlanticists) konverentsil ning mõttekoja German Marshall Fund korraldatud konverentsil

  19. Strategizing NATOs Narratives

    DEFF Research Database (Denmark)

    Nissen, Thomas Elkjer

    2014-01-01

    , implementation structures, and capabilities can be used to inform the construction of strategic narratives in NATO. Using Libya as a case study he explains that the formulation and implementation of strategic narratives in NATO currently is a fragmented process that rarely takes into account the grand strategic...

  20. Emerging methods and tools for environmental risk assessment, decision-making, and policy for nanomaterials: summary of NATO Advanced Research Workshop

    Energy Technology Data Exchange (ETDEWEB)

    Linkov, Igor, E-mail: Igor.Linkov@usace.army.mi [U.S. Army Corps of Engineers, Environmental Laboratory (United States); Steevens, Jeffery, E-mail: Jeffery.A.Steevens@us.army.mi [U.S. Army ERDC (United States); Adlakha-Hutcheon, Gitanjali, E-mail: Gitanjali.Adlakha-Hutcheon@drdc-rddc.gc.c [Defense Research and Development Canada (Canada); Bennett, Erin, E-mail: ebennett@bioengineering.co [Intertox Inc. and Bioengineering Group (United States); Chappell, Mark, E-mail: Mark.a.chappell@usace.army.mi [U.S. Army Corps of Engineers, Environmental Laboratory (United States); Colvin, Vicki, E-mail: colvin@rice.ed [Rice University, ICON (United States); Davis, J. Michael, E-mail: Davis.Jmichael@epa.go [Office of Research and Development, U.S. Environmental Protection Agency, National Center for Environmental Assessment (United States); Davis, Thomas, E-mail: ta.davis@umontreal.c [University of Montreal, Environment Canada and Department of Chemistry (Canada); Elder, Alison, E-mail: Alison_Elder@urmc.rochester.ed [University of Rochester, Department of Environmental Medicine (United States); Foss Hansen, Steffen, E-mail: sfh@er.dtu.d [Technical University of Denmark, Department of Environmental Engineering, NanoDTU (Denmark); Hakkinen, Pertti Bert, E-mail: berthakkinen@gmail.co [Toxicology Excellence for Risk Assessment (TERA) (United States); Hussain, Saber M., E-mail: Saber.Hussain@wpafb.af.mi [Air Force Research Laboratory (United States); Karkan, Delara, E-mail: Delara_karkan@hc-sc.gc.c [Health Canada (Canada); Korenstein, Rafi, E-mail: korens@post.tau.ac.i [Marian Gertner Institute for Medical Nanosystems, Tel Aviv University, Department of Physiology and Pharmacology, Faculty of Medicine (Israel); Lynch, Iseult, E-mail: iseult@fiachra.ucd.i [School of Chemistry and Chemical Biology, University College Dublin, Irish Centre for Colloid Science and Biomaterials (Ireland); Metcalfe, Chris, E-mail: cmetcalfe@trentu.c [Trent University (Canada)

    2009-04-15

    Nanomaterials and their associated technologies hold promising opportunities for the development of new materials and applications in a wide variety of disciplines, including medicine, environmental remediation, waste treatment, and energy conservation. However, current information regarding the environmental effects and health risks associated with nanomaterials is limited and sometimes contradictory. This article summarizes the conclusions of a 2008 NATO workshop designed to evaluate the wide-scale implications (e.g., benefits, risks, and costs) of the use of nanomaterials on human health and the environment. A unique feature of this workshop was its interdisciplinary nature and focus on the practical needs of policy decision makers. Workshop presentations and discussion panels were structured along four main themes: technology and benefits, human health risk, environmental risk, and policy implications. Four corresponding working groups (WGs) were formed to develop detailed summaries of the state-of-the-science in their respective areas and to discuss emerging gaps and research needs. The WGs identified gaps between the rapid advances in the types and applications of nanomaterials and the slower pace of human health and environmental risk science, along with strategies to reduce the uncertainties associated with calculating these risks.

  1. Emerging methods and tools for environmental risk assessment, decision-making, and policy for nanomaterials: summary of NATO Advanced Research Workshop.

    Science.gov (United States)

    Linkov, Igor; Steevens, Jeffery; Adlakha-Hutcheon, Gitanjali; Bennett, Erin; Chappell, Mark; Colvin, Vicki; Davis, J Michael; Davis, Thomas; Elder, Alison; Foss Hansen, Steffen; Hakkinen, Pertti Bert; Hussain, Saber M; Karkan, Delara; Korenstein, Rafi; Lynch, Iseult; Metcalfe, Chris; Ramadan, Abou Bakr; Satterstrom, F Kyle

    2009-04-01

    Nanomaterials and their associated technologies hold promising opportunities for the development of new materials and applications in a wide variety of disciplines, including medicine, environmental remediation, waste treatment, and energy conservation. However, current information regarding the environmental effects and health risks associated with nanomaterials is limited and sometimes contradictory. This article summarizes the conclusions of a 2008 NATO workshop designed to evaluate the wide-scale implications (e.g., benefits, risks, and costs) of the use of nanomaterials on human health and the environment. A unique feature of this workshop was its interdisciplinary nature and focus on the practical needs of policy decision makers. Workshop presentations and discussion panels were structured along four main themes: technology and benefits, human health risk, environmental risk, and policy implications. Four corresponding working groups (WGs) were formed to develop detailed summaries of the state-of-the-science in their respective areas and to discuss emerging gaps and research needs. The WGs identified gaps between the rapid advances in the types and applications of nanomaterials and the slower pace of human health and environmental risk science, along with strategies to reduce the uncertainties associated with calculating these risks.

  2. Eesti miinijahtija NATO õppusel

    Index Scriptorium Estoniae

    2015-01-01

    Suurõppusel Trident Junture osalev miinijahtija Admiral Cowan alustas Hispaania ranniku lähedal Rota sadama ümbruses koos teiste liitlasriikide laevadega tegutsemist NATO kiirreageerimisjõudude merekomponendi õppusel

  3. Recent advances in hematopoietic stem cell biology

    DEFF Research Database (Denmark)

    Bonde, Jesper; Hess, David A; Nolta, Jan A

    2004-01-01

    PURPOSE OF REVIEW: Exciting advances have been made in the field of hematopoietic stem cell biology during the past year. This review summarizes recent progress in the identification, culture, and in vivo tracking of hematopoietic stem cells. RECENT FINDINGS: The roles of Wnt and Notch proteins...... in regulating stem cell renewal in the microenvironment, and how these molecules can be exploited in ex vivo stem cell culture, are reviewed. The importance of identification of stem cells using functional as well as phenotypic markers is discussed. The novel field of nanotechnology is then discussed...... in the context of stem cell tracking in vivo. This review concludes with a section on the unexpected potential of bone marrow-derived stem cells to contribute to the repair of damaged tissues. The contribution of cell fusion to explain the latter phenomenon is discussed. SUMMARY: Because of exciting discoveries...

  4. Contributions to Proceedings from the NATO Advanced Research Workshop on the Seismology of the Sun and the Distant Stars

    Science.gov (United States)

    1985-01-01

    Advanced research results on the seismology of the Sun and distant stars is presented. Topics presented include: (1) detection of global convective wave flows; (2) observation of low degree p-mode oscillations; and (3) techniques for spectral deconvolution.

  5. NATO AND CENTRAL ASIAN STATES: THE PROSPECTS OF COOPERATION

    Directory of Open Access Journals (Sweden)

    A. M. Akmataliyeva

    2012-01-01

    Full Text Available Although cooperation between NATO and Central Asian countries dates back to the 1990s, significant presence of the Alliance in the region is visible throughout the last decade only. The cooperation advanced due to the NATO-led operation in Afghanistan. However, its planned conclusion in 2012 will not lead to the withdrawal of the Alliance from Central Asia. Throughout the last decade NATO developed a network of diversified partnerships with countries of the region. In this process Kazakhstan emerged as its most promising and active partner.

  6. Conclusions of the NATO ARW on Large Scale Computations in Air Pollution Modelling

    DEFF Research Database (Denmark)

    1999-01-01

    Proceedings of the NATO Advanced Research Workshop on Large Scale Computations in Air Pollution Modelling, Sofia, Bulgaria, 6-10 July 1998......Proceedings of the NATO Advanced Research Workshop on Large Scale Computations in Air Pollution Modelling, Sofia, Bulgaria, 6-10 July 1998...

  7. Advanced research workshop "South Caucasus : making the best use of external assistance for stability building and for co-operation with NATO"

    Index Scriptorium Estoniae

    2003-01-01

    Leedu Kaitseministeeriumi poolt 22.-23. septembrini 2003 Vilniuses korraldatud seminaril "South Caucasus: making the best use of external assistance for stability building and for co-operation with NATO" arutati, kas ja kuidas on Lõuna-Kaukaasia regioonis võimalik rakendada Balti riikide julgeolekualase koostöö kogemusi

  8. Analysis of Rotary Aircraft Alternatives for NATO SOF Organic Air Wing

    Science.gov (United States)

    2012-06-01

    the Guidelines for NATO SOF Helicopter Operations,41 the primary skill sets include: (a) Advanced Night Vision Goggle ( NVG ) flying, including NVG ... Helicopter MA Military Assistance MEP(s) Mission Essential Package(s) MFP Multiple Futures Project MTTR Mean Time To Repair NATO North Atlantic...NATO Special Operations Coordination Center NVG Night Vision Goggle O&S Operation and Support OMB Office of Management and Budget SACEUR

  9. The Importance of Taxonomy in Biological Education at Advanced Level.

    Science.gov (United States)

    Honey, John N.; Paxman, Heather M.

    1986-01-01

    Reports on the status of the teaching of taxonomy in advanced biology classes in the United Kingdom. Reviews findings related to examination requirements, the principles, terminology, and methods of taxonomy, the understanding and attitudes of teachers of taxonomy principles, and the position of the topic in the advanced biology syllabus. (ML)

  10. Radiation Protection in Medical Physics : Proceedings of the NATO Advanced Study Institute on Radiation Protection in Medical Physics Activities

    CERN Document Server

    Lemoigne, Yves

    2011-01-01

    This book introduces the fundamental aspects of Radiation Protection in Medical Physics and covers three main themes: General Radiation Protection Principles; Radiobiology Principles; Radiation Protection in Hospital Medical Physics. Each of these topics is developed by analysing the underlying physics principles and their implementation, quality and safety aspects, clinical performance and recent advances in the field. Some issues specific to the individual techniques are also treated, e.g. calculation of patient dose as well as that of workers in hospital, optimisation of equipment used, shielding design of radiation facilities, radiation in oncology such as use of brachytherapy in gynecology or interventional procedures. All topics are presented with didactical language and style, making this book an appropriate reference for students and professionals seeking a comprehensive introduction to the field as well as a reliable overview of the most recent developments.

  11. Report on NATO PTTI

    Science.gov (United States)

    Bishop, J.

    1994-01-01

    The work of the NATO Working Group on precise time and frequency (AC302/SG4/WG4), since its inception in 1988 to the end of 1993, is covered. The aim of the group was to produce STANAG 4430 detailing a standard interface for the transfer of precise time and frequency to assist the interoperability of NATO forces. The design of the interface is outlined together with the concepts leading to the design. The problem of providing and maintaining a traceable UTC in military user systems is described.

  12. NATO explores APS standardisation

    NARCIS (Netherlands)

    Ogorkiewicz, R.M.

    2012-01-01

    Work is proceeding within NATO toward establishing STANAG 4686, which would define the performance levels of armoured vehicles' active protection systems. This would be in addition to the existing, well-established standardisation agreements embodied in STANAG 4569 on the levels of ballistic protect

  13. NATO and Science.

    Science.gov (United States)

    Durand, Henry

    1988-01-01

    Outlines the Third Dimension of NATO. Presses for increased efforts to overcome the disparity in the rate of scientific development among the countries of the alliance. Discusses scientific nobility, the rise of European science, science for stability, environmental protection, and the changed scientific climate. (CW)

  14. Toward metabolic engineering in the context of system biology and synthetic biology: advances and prospects.

    Science.gov (United States)

    Liu, Yanfeng; Shin, Hyun-dong; Li, Jianghua; Liu, Long

    2015-02-01

    Metabolic engineering facilitates the rational development of recombinant bacterial strains for metabolite overproduction. Building on enormous advances in system biology and synthetic biology, novel strategies have been established for multivariate optimization of metabolic networks in ensemble, spatial, and dynamic manners such as modular pathway engineering, compartmentalization metabolic engineering, and metabolic engineering guided by genome-scale metabolic models, in vitro reconstitution, and systems and synthetic biology. Herein, we summarize recent advances in novel metabolic engineering strategies. Combined with advancing kinetic models and synthetic biology tools, more efficient new strategies for improving cellular properties can be established and applied for industrially important biochemical production.

  15. Advances in Retinal Stem Cell Biology

    Directory of Open Access Journals (Sweden)

    Andrea S Viczian

    2013-01-01

    Full Text Available Tremendous progress has been made in recent years to generate retinal cells from pluripotent cell sources. These advances provide hope for those suffering from blindness due to lost retinal cells. Understanding the intrinsic genetic network in model organisms, like fly and frog, has led to a better understanding of the extrinsic signaling pathways necessary for retinal progenitor cell formation in mouse and human cell cultures. This review focuses on the culture methods used by different groups, which has culminated in the generation of laminated retinal tissue from both embryonic and induced pluripotent cells. The review also briefly describes advances made in transplantation studies using donor retinal progenitor and cultured retinal cells.

  16. NATO: Revisiting American Commitment

    Science.gov (United States)

    2013-03-01

    been short sighted. Kurt Volker , 4 former U.S. ambassador to NATO, posits that it was this decision by the United States in 2001 to set aside...ineffective with “virtually no prospect that their soldiers would fire a shot in anger.”10 This situation in turn reduces the overall morale of the force...Potomac Books, 2011), 5. 3 Ibid., 47. 4 Kurt Volker , “Reaffirming Transatlantic Unity”, Policy Review, Hoover Institution, March 30, 2012. 5

  17. The NATO thesaurus project

    Science.gov (United States)

    Krueger, Jonathan

    1990-01-01

    This document describes functionality to be developed to support the NATO technical thesaurus. Described are the specificity of the thesaurus structure and function; the distinction between the thesaurus information and its representation in a given online, machine readable, or printed form; the enhancement of the thesaurus with the assignment of COSATI codes (fields and groups) to posting terms, the integration of DTIC DRIT and NASA thesauri related terminology, translation of posting terms into French; and the provision of a basis for system design.

  18. 32 CFR 728.42 - NATO.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false NATO. 728.42 Section 728.42 National Defense... § 728.42 NATO. (a) NATO SOFA nations. Belgium, Canada, Denmark, Federal Republic of Germany, France... conditions set forth. (1) Members of NATO military services and their dependents. Military personnel of...

  19. NATO Standards for Virtual Ships

    NARCIS (Netherlands)

    Kraker, J.K. de; Duncan, J.; Budde, E.W.; Reading, R.

    2005-01-01

    The NATO Naval Armaments Group Sub-Group 61 on Virtual Ships has been chartered to establish NATO standards for modeling and simulation applied to ship acquisition. Its objective is to enable multi-national simulation re-use and interoperability, as well as simulation composability. Technical activi

  20. NATO: In-orbit experience

    Science.gov (United States)

    Capulli, J. J.

    1980-01-01

    The performance of the NATO-111-A and NATO 111-B satellite battery is reported. The electrical power subsystem is briefly described. The electrical characteristics and the reconditioning experience of the batteries is cited. The in-orbit experience is compared with results of preflight accelerated life tests.

  1. Rhabdomyosarcoma: Advances in Molecular and Cellular Biology

    Directory of Open Access Journals (Sweden)

    Xin Sun

    2015-01-01

    Full Text Available Rhabdomyosarcoma (RMS is the most common soft tissue malignancy in childhood and adolescence. The two major histological subtypes of RMS are alveolar RMS, driven by the fusion protein PAX3-FKHR or PAX7-FKHR, and embryonic RMS, which is usually genetically heterogeneous. The prognosis of RMS has improved in the past several decades due to multidisciplinary care. However, in recent years, the treatment of patients with metastatic or refractory RMS has reached a plateau. Thus, to improve the survival rate of RMS patients and their overall well-being, further understanding of the molecular and cellular biology of RMS and identification of novel therapeutic targets are imperative. In this review, we describe the most recent discoveries in the molecular and cellular biology of RMS, including alterations in oncogenic pathways, miRNA (miR, in vivo models, stem cells, and important signal transduction cascades implicated in the development and progression of RMS. Furthermore, we discuss novel potential targeted therapies that may improve the current treatment of RMS.

  2. New advances in pollination biology and the studies in China

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Pollination biology is the study of the various biological features in relation to the event of pollen transfer. It is one of the central concerns of plant reproductive ecology and evolutionary biology. In this paper, we attempt to introduce the main advances and some new interests in pollination biology and make a brief review of the research work that has been done in China in recent years. We also give some insights into the study that we intend to carry out in this field in the future.

  3. USA suursaadik NATO-s : oleme valmis tulema liitlasi kaitsma / Kurt Volker ; interv. Liisa Past

    Index Scriptorium Estoniae

    Volker, Kurt

    2008-01-01

    USA suursaadik NATO juures on seisukohal, et Ukrainal on veel pikk tee NATO liikmesuse saavutamiseks; ta ei usu, et Venemaa plaaniks rünnata ühtegi NATO liikmesriiki. Afganistani ja Iraagi julgeolekust

  4. Imaging morphogenesis: technological advances and biological insights.

    Science.gov (United States)

    Keller, Philipp J

    2013-06-01

    Morphogenesis, the development of the shape of an organism, is a dynamic process on a multitude of scales, from fast subcellular rearrangements and cell movements to slow structural changes at the whole-organism level. Live-imaging approaches based on light microscopy reveal the intricate dynamics of this process and are thus indispensable for investigating the underlying mechanisms. This Review discusses emerging imaging techniques that can record morphogenesis at temporal scales from seconds to days and at spatial scales from hundreds of nanometers to several millimeters. To unlock their full potential, these methods need to be matched with new computational approaches and physical models that help convert highly complex image data sets into biological insights.

  5. Emerging methods and tools for environmental risk assessment, decision-making, and policy for nanomaterials: summary of NATO Advanced Research Workshop

    DEFF Research Database (Denmark)

    Linkov, I; Steevens, J; Adlakha-Hutcheon, G;

    2009-01-01

    the environmental effects and health risks associated with nanomaterials is limited and sometimes contradictory. This article summarizes the conclusions of a 2008 NATO workshop designed to evaluate the wide-scale implications (e.g., benefits, risks, and costs) of the use of nanomaterials on human health...... and the environment. A unique feature of this workshop was its interdisciplinary nature and focus on the practical needs of policy decision makers. Workshop presentations and discussion panels were structured along four main themes: technology and benefits, human health risk, environmental risk, and policy......Nanomaterials and their associated technologies hold promising opportunities for the development of new materials and applications in a wide variety of disciplines, including medicine, environmental remediation, waste treatment, and energy conservation. However, current information regarding...

  6. NATO suurendab kohalolu

    Index Scriptorium Estoniae

    2014-01-01

    Põhja-Atlandi nõukogu kiitis Brüsselis heaks ettepanekud heidutuse ja kaitse suurendamiseks Ida-Euroopas. NATO peasekretäri Anders Fogh Rasmusseni sõnul suurendatakse seoses süveneva kriisiga Ukrainas heidutust Balti riikides lähipäevil. "Meil hakkab olema rohkem lennukeid õhus, rohkem laevu merel ning suurem valmisoleks maal," ütles Anders Fogh Rasmussen. Näiteks hakkavad õhuruumi turvavad lennukid rohkem lendama üle Balti riikide, liitlaste laevad paigutatakse Balti merele

  7. NATO Advanced Research Workshop: Optics of Biological Particles. Held in Novosibirsk, Russia on 3-6 Oct 2005

    Science.gov (United States)

    2005-01-01

    non-destructive character. It makes the method very at- tractive for pharmaceutical and biotechnological industries applications. Liposomes are close...Martinez, Javier A., B.Sc. (in Physics) Institute of Materials and Reagents (IMRE), University of Havana Zapata y G, El Vedado, Plaza de la Revolucion

  8. Using Advance Organizers to Enhance Students' Motivation in Learning Biology

    Science.gov (United States)

    Shihusa, Hudson; Keraro, Fred N.

    2009-01-01

    This study investigated the effect of using advance organizers on students' motivation to learn biology. The research design used was quasi-experimental design where the non-randomised Solomon Four group was adopted. The focus was on the topic pollution. The sample comprised of 166 form three (third grade in the secondary school cycle) students in…

  9. A first attempt to bring computational biology into advanced high school biology classrooms.

    Directory of Open Access Journals (Sweden)

    Suzanne Renick Gallagher

    2011-10-01

    Full Text Available Computer science has become ubiquitous in many areas of biological research, yet most high school and even college students are unaware of this. As a result, many college biology majors graduate without adequate computational skills for contemporary fields of biology. The absence of a computational element in secondary school biology classrooms is of growing concern to the computational biology community and biology teachers who would like to acquaint their students with updated approaches in the discipline. We present a first attempt to correct this absence by introducing a computational biology element to teach genetic evolution into advanced biology classes in two local high schools. Our primary goal was to show students how computation is used in biology and why a basic understanding of computation is necessary for research in many fields of biology. This curriculum is intended to be taught by a computational biologist who has worked with a high school advanced biology teacher to adapt the unit for his/her classroom, but a motivated high school teacher comfortable with mathematics and computing may be able to teach this alone. In this paper, we present our curriculum, which takes into consideration the constraints of the required curriculum, and discuss our experiences teaching it. We describe the successes and challenges we encountered while bringing this unit to high school students, discuss how we addressed these challenges, and make suggestions for future versions of this curriculum.We believe that our curriculum can be a valuable seed for further development of computational activities aimed at high school biology students. Further, our experiences may be of value to others teaching computational biology at this level. Our curriculum can be obtained at http://ecsite.cs.colorado.edu/?page_id=149#biology or by contacting the authors.

  10. A first attempt to bring computational biology into advanced high school biology classrooms.

    Science.gov (United States)

    Gallagher, Suzanne Renick; Coon, William; Donley, Kristin; Scott, Abby; Goldberg, Debra S

    2011-10-01

    Computer science has become ubiquitous in many areas of biological research, yet most high school and even college students are unaware of this. As a result, many college biology majors graduate without adequate computational skills for contemporary fields of biology. The absence of a computational element in secondary school biology classrooms is of growing concern to the computational biology community and biology teachers who would like to acquaint their students with updated approaches in the discipline. We present a first attempt to correct this absence by introducing a computational biology element to teach genetic evolution into advanced biology classes in two local high schools. Our primary goal was to show students how computation is used in biology and why a basic understanding of computation is necessary for research in many fields of biology. This curriculum is intended to be taught by a computational biologist who has worked with a high school advanced biology teacher to adapt the unit for his/her classroom, but a motivated high school teacher comfortable with mathematics and computing may be able to teach this alone. In this paper, we present our curriculum, which takes into consideration the constraints of the required curriculum, and discuss our experiences teaching it. We describe the successes and challenges we encountered while bringing this unit to high school students, discuss how we addressed these challenges, and make suggestions for future versions of this curriculum.We believe that our curriculum can be a valuable seed for further development of computational activities aimed at high school biology students. Further, our experiences may be of value to others teaching computational biology at this level. Our curriculum can be obtained at http://ecsite.cs.colorado.edu/?page_id=149#biology or by contacting the authors.

  11. NATO and nonproliferation: A critical appraisal

    Energy Technology Data Exchange (ETDEWEB)

    Dembinski, M.; Kelle, A.; Mueller, H.

    1994-04-01

    This paper analyses NATO`s past, actual and potential impact on the nonproliferation regime. It starts by looking back at the useful function NATO has performed throughout its existence in discouraging motivations by its non-nuclear weapon member-states from going nuclear. It then asks whether that role is likely to continue. The study goes on to ask whether NATO`s doctrine and practice may also pose risks to the regime, and investigates what benefits and risks may emerge from future counterproliferation activities. In conclusion, the paper suggests a modest but useful contribution NATO could make to strengthen the nonproliferation regime, provided major flaws are avoided. (orig.)

  12. NATO "readjustments" likely / Jeremy Bransten

    Index Scriptorium Estoniae

    Bransten, Jeremy

    2003-01-01

    USA kaitseminister Donald Rumsfeld ütles, et Washington võib lõpetada NATO peakorteri ehituse finantseerimise ja USA sõjaväelaste saatmise Belgiasse kui viimane ei muuda oma sõjakuritegude-alast seadusandlust

  13. Advances in Neuroscience and the Biological and Toxin Weapons Convention

    Directory of Open Access Journals (Sweden)

    Malcolm Dando

    2011-01-01

    Full Text Available This paper investigates the potential threat to the prohibition of the hostile misuse of the life sciences embodied in the Biological and Toxin Weapons Convention from the rapid advances in the field of neuroscience. The paper describes how the implications of advances in science and technology are considered at the Five Year Review Conferences of the Convention and how State Parties have developed their appreciations since the First Review Conference in 1980. The ongoing advances in neurosciences are then assessed and their implications for the Convention examined. It is concluded that State Parties should consider a much more regular and systematic review system for such relevant advances in science and technology when they meet at the Seventh Review Conference in late 2011, and that neuroscientists should be much more informed and engaged in these processes of protecting their work from malign misuse.

  14. Advances in neuroscience and the biological and toxin weapons convention.

    Science.gov (United States)

    Dando, Malcolm

    2011-01-01

    This paper investigates the potential threat to the prohibition of the hostile misuse of the life sciences embodied in the Biological and Toxin Weapons Convention from the rapid advances in the field of neuroscience. The paper describes how the implications of advances in science and technology are considered at the Five Year Review Conferences of the Convention and how State Parties have developed their appreciations since the First Review Conference in 1980. The ongoing advances in neurosciences are then assessed and their implications for the Convention examined. It is concluded that State Parties should consider a much more regular and systematic review system for such relevant advances in science and technology when they meet at the Seventh Review Conference in late 2011, and that neuroscientists should be much more informed and engaged in these processes of protecting their work from malign misuse.

  15. Can NATO Practice Grand Strategy?

    DEFF Research Database (Denmark)

    Barfoed, Jacob

    2014-01-01

    In its intervention in Libya, not only did NATO fail to produce a military strategy and a campaign plan before commencing military operations, what is more worrisome was the lack of political guidance to and control of the Joint Task Force.......In its intervention in Libya, not only did NATO fail to produce a military strategy and a campaign plan before commencing military operations, what is more worrisome was the lack of political guidance to and control of the Joint Task Force....

  16. Where Is NATO Heading for?

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ A NATO summit was held on April 2-4 of this year in Bucharest,the capital of Romania.It was the last meeting the U.S.President George W.Bush attended in his presidential term.The outgoing Russian President A.Putin, also took part in the "NATO-Russia Council" meeting.Therefore,this summit attracted particular attention.

  17. NATO Conference on Molecular Metals

    CERN Document Server

    1979-01-01

    During the past few years there has been intense research activity in the design, synthesis, and characterization of materials which are formed from molecular precursors, and which have high or metal-like electrical conductivities, i.e. dcr/dT < O. It has been widely supposed that these new materials, which are commonly called molecular metals, would be pressed into service, for example as devices. Up to now, widespread, practical applications of these sub­ stances have not developed. The NATO Advanced Research Institute on Molecular Metals at Les Arcs, France, September 10-16, 1978 was organized to discuss the scientific and technological potential of research and development in this field. The proceedings of the Institute constitute this book. Several lectures were devoted to the assessment of the present status of research on systems which serve to define major components of the field. The systems which were discussed included TTF-TCNQ, platinum chain compounds, (SN)x, polyacetylene, polydiacetylene, g...

  18. Advancing metabolic engineering through systems biology of industrial microorganisms

    DEFF Research Database (Denmark)

    Dai, Zongjie; Nielsen, Jens

    2015-01-01

    resources. The objective of systems biology is to gain a comprehensive and quantitative understanding of living cells and can hereby enhance our ability to characterize and predict cellular behavior. Systems biology of industrial microorganisms is therefore valuable for metabolic engineering. Here we review...... the application of systems biology tools for the identification of metabolic engineering targets which may lead to reduced development time for efficient cell factories. Finally, we present some perspectives of systems biology for advancing metabolic engineering further.......Development of sustainable processes to produce bio-based compounds is necessary due to the severe environmental problems caused by the use of fossil resources. Metabolic engineering can facilitate the development of highly efficient cell factories to produce these compounds from renewable...

  19. CAM Modalities Can Stimulate Advances in Theoretical Biology

    Directory of Open Access Journals (Sweden)

    Alex Hankey

    2005-01-01

    Full Text Available Most complementary medicine is distinguished by not being supported by underlying theory accepted by Western science. However, for those who accept their validity, complementary and alternative medicine (CAM modalities offer clues to understanding physiology and medicine more deeply. Ayurveda and vibrational medicine are stimulating new approaches to biological regulation. The new biophysics can be integrated to yield a single consistent theory, which may well underly much of CAM—a true ‘physics of physick’. The resulting theory seems to be a new, fundamental theory of health and etiology. It suggests that many CAM approaches to health care are scientifically in advance of those based on current Western biology. Such theories may well constitute the next steps in our scientific understanding of biology itself. If successfully developed, these ideas could result in a major paradigm shift in both biology and medicine, which will benefit all interested parties—consumers, health professionals, scientists, institutions and governments.

  20. Advancing metabolic engineering through systems biology of industrial microorganisms.

    Science.gov (United States)

    Dai, Zongjie; Nielsen, Jens

    2015-12-01

    Development of sustainable processes to produce bio-based compounds is necessary due to the severe environmental problems caused by the use of fossil resources. Metabolic engineering can facilitate the development of highly efficient cell factories to produce these compounds from renewable resources. The objective of systems biology is to gain a comprehensive and quantitative understanding of living cells and can hereby enhance our ability to characterize and predict cellular behavior. Systems biology of industrial microorganisms is therefore valuable for metabolic engineering. Here we review the application of systems biology tools for the identification of metabolic engineering targets which may lead to reduced development time for efficient cell factories. Finally, we present some perspectives of systems biology for advancing metabolic engineering further.

  1. NATO Advanced Study Institute on Physical Processes in Laser-Materials Interaction, which was the 9th course of the Europhysics School of Quantum Electronics

    CERN Document Server

    1983-01-01

    It is a pleasure to write a few words as an introduction to the proceedings of the 1980 NATO ASI on "Physical Processes in Laser­ Naterial Interaction." This ASI is the ninth course of a series devoted to lasers and their applications, held under the responsibility of the Quantum Electronics Division of the European Physical Society, and for this reason known as the "Europhysics School of Quantum Electronics." Since 1971 the School has been operating with the joint direc­ tion of myself as representative of the academic research, and Dr. D. Roess (formerly with Siemens AEG, Munich, and now with Sick, Optik und Electronik, GmbH, Munich) for the industrial applications. Indeed the aim of the School is to alternate fundamental and applied frontier topics in the area of quantum electronics and modern optics, in order to introduce young research people from universities and industrial R&D laboratories to the new aspects of research opened by the laser.

  2. Perspectives on NATO Nuclear Policy

    Energy Technology Data Exchange (ETDEWEB)

    Lunn, Simon [Royal United Services Institute for Defense and Security Studies - RUSI, Whitehall, London, SW1A 2ET (United Kingdom); Larsen, Jeffrey [Larsen Consulting Group, 3710 Woodland Dr Ste 2100, Anchorage, AK 99517 (United States); Yost, David [Naval Postgraduate School, 1 University Circle, Monterey, CA 93943 (United States); Kamp, Karl-Heinz [NATO Defense College, Via Giorgio Pelosi 1, 00143, Roma (Italy); Edelman, Eric [Center for Strategic and Budgetary Assessments - CSBA, 1667 K Sreet NW, Suite 900, Washington, DC, 20006 (United States); Valasek, Tomas [Centre for European Reform - CER, 14 Great College Street, Westminster, London, SW1P 3RX (United Kingdom); Garcia Cantalapiedra, David [Universidad Complutense de Madrid, Ciudad Universitaria, 28040 Madrid (Spain)

    2011-05-26

    NATO will shortly revisit the question of its nuclear policy and posture as part of the ongoing deterrence and defense posture review (DDPR). This assessment of its nuclear requirements will be take place against the background of two parallel and potentially competing commitments: first, the general support for the goal of reducing and eventually eliminating nuclear weapons with the related question of how NATO should contribute to this goal; second, the commitment that in considering the role of nuclear weapons the priority for NATO members is the maintenance of solidarity and cohesion and the consequent determination that decisions on nuclear policy will be taken by the Alliance collectively. There are forcefully expressed arguments on both sides of the debate over whether to maintain or eliminate the remaining arsenal of U.S. nuclear weapons assigned to NATO. On the one hand, they provide coupling, transatlantic links, military capabilities against an uncertain future, and risk and burden sharing. On the other, some allies see benefits to further reductions in the remaining arsenal in the cause of global disarmament. This study presents first the questions and issues for NATO and the future alternatives for NATO nuclear policy. Then, the views from United States, Germany, Turkey, Central and Eastern Europe, Italy and Spain are successively reviewed

  3. Afghanistan after NATO Withdrawal

    Directory of Open Access Journals (Sweden)

    Bojor Laviniu

    2015-06-01

    Full Text Available The conclusion of a conflict, called by some American analysts as “America’s Longest War”, after the withdrawal of the majority of NATO military forces, requires a careful analysis of the conditions and security environment that ISAF mission, International Security Afghan Forces, leaves as legacy to the Afghan military forces. The transfer of authority towards a strong government, recognized by most Afghan provinces, and benefiting from the support of national military forces able to cope with terrorist and insurgent threats on its own, are the minimum and necessary conditions leading the country towards a stable and secure environment and towards a sustainable development. Given these realities, any approach on the consequences of the transition towards self-sustainable governance becomes interesting and timely for any military political study. These are the prospects that we propose in our paper.

  4. NATO Telecommunications Symposium

    CERN Document Server

    Lucas, William; Conrath, David

    1978-01-01

    This book contains the proceedings of the first international symposium devoted to research on the evaluation and planning of new person-to-person telecommunication systems. It was sponsored by NATO's Special Programme Panel on Systems Science and took place, in September 1977, at the University of Bergamo in the north of Italy. Telecommunication systems which provide for communication be­ tween people, rather than computers or other instruments, are of two kinds. There are mass communication systems (broadcast radio and television) and interpersonal systems (for example, the telephone and Telex) which join together individuals or small groups. Here we have included in the interpersonal category certain systems for re­ trieving information from computers, essentially those systems in which the role of the computer 1s primarily to act as a store and to identify that information which best fits a user's request. (This excludes management information systems in which the computer performs important transformat...

  5. NATO juht: Eestile otsest ohtu pole

    Index Scriptorium Estoniae

    2014-01-01

    NATO peasekretär Anders Fogh Rasmussen ütles pressikonverentsil, et kuna Eesti on NATO liige, siis otsest agressiooniohtu Eestile praegu ei ole, kuid siiski on väga tähtis kollektiivkaitse tugevdamine

  6. Advanced Tomography Techniques For Inorganic, Organic, and Biological Materials

    Energy Technology Data Exchange (ETDEWEB)

    Evans, James E.; Friedrich, Heiner

    2016-07-01

    Three-dimensional (3D) tomography using electrons and x-rays has pushed our understanding of the micro- and nanoscale spatial organization for biological, organic and inorganic materials. While significant impact has already been realized from tomography applications, new advanced methods are quickly expanding the versatility of this approach to better link structure, composition and function of complex 3D assemblies across multiple scales. In this article we highlight several frontiers where new developments in tomography are empowering all new science across biology, chemistry and physics. The 5 articles that appear in this MRS Bulletin Issue describe in detail these latest developments in analytical electron tomography, atomic resolution electron tomography, advanced recording schemes in scanning transmission electron (STEM) tomography, cryo-STEM tomography of whole cells, and multiscale correlative tomography.

  7. Muutuv NATO, muutuv Põhjala / Mart Helme

    Index Scriptorium Estoniae

    Helme, Mart, 1949-

    2002-01-01

    Ilmunud ka: Hiiumaa 23. november lk. 5. Millisesse NATO-sse Eesti läheb ja kuidas mõjutab NATO laienemine Põhjala riike ning Venemaad. Vt. samas: Hinnang NATO laienemisele: George Robertson, George W. Bush, Sergei Ivanov (Venemaa kaitseminister), Gennadi Zjuganov

  8. Invited Review Article: Advanced light microscopy for biological space research

    Science.gov (United States)

    De Vos, Winnok H.; Beghuin, Didier; Schwarz, Christian J.; Jones, David B.; van Loon, Jack J. W. A.; Bereiter-Hahn, Juergen; Stelzer, Ernst H. K.

    2014-10-01

    As commercial space flights have become feasible and long-term extraterrestrial missions are planned, it is imperative that the impact of space travel and the space environment on human physiology be thoroughly characterized. Scrutinizing the effects of potentially detrimental factors such as ionizing radiation and microgravity at the cellular and tissue level demands adequate visualization technology. Advanced light microscopy (ALM) is the leading tool for non-destructive structural and functional investigation of static as well as dynamic biological systems. In recent years, technological developments and advances in photochemistry and genetic engineering have boosted all aspects of resolution, readout and throughput, rendering ALM ideally suited for biological space research. While various microscopy-based studies have addressed cellular response to space-related environmental stressors, biological endpoints have typically been determined only after the mission, leaving an experimental gap that is prone to bias results. An on-board, real-time microscopical monitoring device can bridge this gap. Breadboards and even fully operational microscope setups have been conceived, but they need to be rendered more compact and versatile. Most importantly, they must allow addressing the impact of gravity, or the lack thereof, on physiologically relevant biological systems in space and in ground-based simulations. In order to delineate the essential functionalities for such a system, we have reviewed the pending questions in space science, the relevant biological model systems, and the state-of-the art in ALM. Based on a rigorous trade-off, in which we recognize the relevance of multi-cellular systems and the cellular microenvironment, we propose a compact, but flexible concept for space-related cell biological research that is based on light sheet microscopy.

  9. Invited review article: Advanced light microscopy for biological space research.

    Science.gov (United States)

    De Vos, Winnok H; Beghuin, Didier; Schwarz, Christian J; Jones, David B; van Loon, Jack J W A; Bereiter-Hahn, Juergen; Stelzer, Ernst H K

    2014-10-01

    As commercial space flights have become feasible and long-term extraterrestrial missions are planned, it is imperative that the impact of space travel and the space environment on human physiology be thoroughly characterized. Scrutinizing the effects of potentially detrimental factors such as ionizing radiation and microgravity at the cellular and tissue level demands adequate visualization technology. Advanced light microscopy (ALM) is the leading tool for non-destructive structural and functional investigation of static as well as dynamic biological systems. In recent years, technological developments and advances in photochemistry and genetic engineering have boosted all aspects of resolution, readout and throughput, rendering ALM ideally suited for biological space research. While various microscopy-based studies have addressed cellular response to space-related environmental stressors, biological endpoints have typically been determined only after the mission, leaving an experimental gap that is prone to bias results. An on-board, real-time microscopical monitoring device can bridge this gap. Breadboards and even fully operational microscope setups have been conceived, but they need to be rendered more compact and versatile. Most importantly, they must allow addressing the impact of gravity, or the lack thereof, on physiologically relevant biological systems in space and in ground-based simulations. In order to delineate the essential functionalities for such a system, we have reviewed the pending questions in space science, the relevant biological model systems, and the state-of-the art in ALM. Based on a rigorous trade-off, in which we recognize the relevance of multi-cellular systems and the cellular microenvironment, we propose a compact, but flexible concept for space-related cell biological research that is based on light sheet microscopy.

  10. Invited Review Article: Advanced light microscopy for biological space research

    Energy Technology Data Exchange (ETDEWEB)

    De Vos, Winnok H., E-mail: winnok.devos@uantwerpen.be [Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp, Antwerp (Belgium); Cell Systems and Imaging Research Group, Department of Molecular Biotechnology, Ghent University, Ghent (Belgium); Beghuin, Didier [Lambda-X, Nivelles (Belgium); Schwarz, Christian J. [European Space Agency (ESA), ESTEC, TEC-MMG, Noordwijk (Netherlands); Jones, David B. [Institute for Experimental Orthopaedics and Biomechanics, Philipps University, Marburg (Germany); Loon, Jack J. W. A. van [Department of Oral and Maxillofacial Surgery/Oral Pathology, VU University Medical Center and Department of Oral Cell Biology, Academic Centre for Dentistry Amsterdam, Amsterdam (Netherlands); Bereiter-Hahn, Juergen; Stelzer, Ernst H. K. [Physical Biology, BMLS (FB15, IZN), Goethe University, Frankfurt am Main (Germany)

    2014-10-15

    As commercial space flights have become feasible and long-term extraterrestrial missions are planned, it is imperative that the impact of space travel and the space environment on human physiology be thoroughly characterized. Scrutinizing the effects of potentially detrimental factors such as ionizing radiation and microgravity at the cellular and tissue level demands adequate visualization technology. Advanced light microscopy (ALM) is the leading tool for non-destructive structural and functional investigation of static as well as dynamic biological systems. In recent years, technological developments and advances in photochemistry and genetic engineering have boosted all aspects of resolution, readout and throughput, rendering ALM ideally suited for biological space research. While various microscopy-based studies have addressed cellular response to space-related environmental stressors, biological endpoints have typically been determined only after the mission, leaving an experimental gap that is prone to bias results. An on-board, real-time microscopical monitoring device can bridge this gap. Breadboards and even fully operational microscope setups have been conceived, but they need to be rendered more compact and versatile. Most importantly, they must allow addressing the impact of gravity, or the lack thereof, on physiologically relevant biological systems in space and in ground-based simulations. In order to delineate the essential functionalities for such a system, we have reviewed the pending questions in space science, the relevant biological model systems, and the state-of-the art in ALM. Based on a rigorous trade-off, in which we recognize the relevance of multi-cellular systems and the cellular microenvironment, we propose a compact, but flexible concept for space-related cell biological research that is based on light sheet microscopy.

  11. Fluorescent Dendrimer Nanoconjugates as Advanced Probes for Biological Imaging

    Science.gov (United States)

    Reilly, Daniel; Kim, Sung Hoon; Katzenellenbogen, John A.; Schroeder, Charles M.

    2014-03-01

    Recent advances in fluorescence microscopy have enabled improvements in spatial resolution for biological imaging. However, there is a strong need for development of advanced fluorescent probes to enable a molecular-scale understanding of biological events. In this work, we report the development of a new class of probes for fluorescence imaging based on dye-conjugated dendrimer nanoconjugates. We utilize molecular-scale dendritic scaffolds as fluorescent probes, thereby enabling conjugation of multiple dyes and linkers to the scaffold periphery. In particular, we use polyamidoamine dendrimers as molecular scaffolds, wherein dye conjugation can be varied over a wide range. Single molecule fluorescence imaging shows that dendrimer nanoconjugates are far brighter than single fluorophores, resulting in increased localization precision. In addition, we further developed a new set of remarkably photostable probes by conjugating photoprotective triplet state quenchers directly onto the dendritic scaffold. We observe large increases in the photobleaching times compared to single dyes and reduced transient dark states (blinking). Overall, we believe that these new probes will allow for single molecule imaging over long time scales, enabling new vistas in biological imaging.

  12. NATO's Strategic Partnership with Ukraine

    DEFF Research Database (Denmark)

    Breitenbauch, Henrik Ø.

    2014-01-01

    Russian actions in Ukraine have altered the security land- scape in Europe, highlighting a renewed emphasis on the differences between members and non-members. In this context, NATO must a) create a strategic understanding of partnerships as something that can be transformative, even if it will n......Russian actions in Ukraine have altered the security land- scape in Europe, highlighting a renewed emphasis on the differences between members and non-members. In this context, NATO must a) create a strategic understanding of partnerships as something that can be transformative, even...... if it will not lead to membership in the short or even long term, and b) build such a strategic relationship with Ukraine. In sum, the Russian-induced Ukraine crisis should spur the reform of NATO partnerships – with Ukraine as a case in point....

  13. Advances in the Chemical Analysis and Biological Activities of Chuanxiong

    Directory of Open Access Journals (Sweden)

    Jin-Ao Duan

    2012-09-01

    Full Text Available Chuanxiong Rhizoma (Chuan-Xiong, CX, the dried rhizome of Ligusticum chuanxiong Hort. (Umbelliferae, is one of the most popular plant medicines in the World. Modern research indicates that organic acids, phthalides, alkaloids, polysaccharides, ceramides and cerebrosides are main components responsible for the bioactivities and properties of CX. Because of its complex constituents, multidisciplinary techniques are needed to validate the analytical methods that support CX’s use worldwide. In the past two decades, rapid development of technology has advanced many aspects of CX research. The aim of this review is to illustrate the recent advances in the chemical analysis and biological activities of CX, and to highlight new applications and challenges. Emphasis is placed on recent trends and emerging techniques.

  14. Biomass and biofuels from microalgae advances in engineering and biology

    CERN Document Server

    Moheimani, Navid Reza; de Boer, Karne; Bahri, Parisa

    2015-01-01

    This comprehensive book details the most recent advances in the microalgae biological sciences and engineering technologies for biomass and biofuel production in order to meet the ongoing need for new and affordable sources of food, chemicals and energy for future generations. The chapters explore new microalgae cultivation techniques, including solid (biofilm) systems, and heterotrophic production methods, while also critically investigating topics such as combining wastewater as a source of nutrients, the effect of CO2 on growth, and converting biomass to methane through anaerobi

  15. NATO to the Baltic states : "You're In!"

    Index Scriptorium Estoniae

    2003-01-01

    Järelkajadest ja reaktsioonidest 21. nov. toimunud Praha tippkohtumisele, kus teiste hulgas said kolm Balti riiki kutse NATO-ga liitumisläbirääkimistele. Lisa: Quotes on NATO (tsitaate NATO laienemise kohta)

  16. 10 YEARS AFTER NATO MEMBERSHIP

    DEFF Research Database (Denmark)

    ”10 years after NATO Membership. An Anniversary in the Shadow of a Crisis”, indeholder artikler fra politiske aktører, diplomater og forskere, der alle bidrog til til konferencen af samme navn, hvor den 10-året for baltisk medlemskab af NATO var omdrejningspunktet. Udover den danske...... forsvarsminister, er den estiske og litauiske forsvarsminister og NATO’s vicegeneralsekretær blandt bidragyderne. Konferencens formål var at fejre, inddrage og diskutere 10 års forsvarspolitisk NATO-samarbejde i Østersøområdet. Den internationale udvikling i Europa betød at konferencens dagsorden i stedet for kom...... billede af hvordan den russiske aggression på Krimhalvøen blev italesat af de repræsenterede landes Forsvarsministre samt fra hovedkvarteret i NATO. Konferencen blev afholdt tidligere i år i København, og var et resultat af et tæt samarbejde mellem Forsvarsakademiet, Forsvarsministeriet og ambassadørerne...

  17. Technical Reference Manual: NATO Planning Guide for the Estimation of Chemical, Biological, Radiological, and Nuclear (CBRN), Casualties, Allied Medical Publication-8(C)

    Science.gov (United States)

    2010-08-01

    chemical blister agent HD (distilled mustard); the biological agents causing anthrax, botulism, pneumonic plague, smallpox, and Venezuelan equine ...Countermeasures—Vaccination/ Antibiotic Prophylaxis ............181 7. Literature Review and Parameter Development .......................................181 8...203 4. Venezuelan Equine Encephalitis (VEE) ....................................................212 E

  18. Trusting Relationships in the NATO Alliance

    DEFF Research Database (Denmark)

    Keating, Vincent Charles

    trust-building among its members, this paper represents an initial attempt to consider how the question of trust can be considered with respect to the existing literature on both alliances and NATO. In doing so, it brings together three literatures: trust theory, alliance theory, and NATO studies......, in order to reveal the points of intersection that might help us to understand how and why trusting relationships can be formed within the NATO alliance....

  19. NATO-Russian relation status and prospectives

    OpenAIRE

    AKTI, Serkan

    2004-01-01

    Approved for public release; distribution in unlimited. Since the end of the Cold War, NATO has attributed great importance to the development of cooperation with Russia. This thesis, first, evaluates the main developments in NATO - Russian relations since 1991. Although Moscow and the Alliance established a NATO - Russia Council (NRC) and asserted the initiation of a qualitatively new relationship, Russia still needs to fulfill some requirements for catching up the Western standards. Russ...

  20. NATO i krigen mot terror : En analyse av NATOs rolle i Afghanistan etter 11. september

    OpenAIRE

    Berg-Hansen, Susanne

    2007-01-01

    Denne oppgaven studerer NATOs rolle i den USA-ledede Operation Enduring Freedom i Afghanistan. Noen timer etter terrorangrepet mot USA 11. september 2001, påkalte NATO for første gang i historien sin grunnpilar, Artikkel 5 i NATO-traktaten, som fastslår at et angrep på ett av medlemmene er et angrep på alle NATO-landene. Til tross for alliansens påkallelse av Artikkel 5, ble NATO stående på sidelinjen i hovedfasen av "Operation Enduring Freedom". USA valgte å gjennomføre mesteparten av kamp...

  1. Molecular Imaging : Computer Reconstruction and Practice - Proceedings of the NATO Advanced Study Institute on Molecular Imaging from Physical Principles to Computer Reconstruction and Practice

    CERN Document Server

    Lemoigne, Yves

    2008-01-01

    This volume collects the lectures presented at the ninth ESI School held at Archamps (FR) in November 2006 and is dedicated to nuclear physics applications in molecular imaging. The lectures focus on the multiple facets of image reconstruction processing and management and illustrate the role of digital imaging in clinical practice. Medical computing and image reconstruction are introduced by analysing the underlying physics principles and their implementation, relevant quality aspects, clinical performance and recent advancements in the field. Several stages of the imaging process are specifically addressed, e.g. optimisation of data acquisition and storage, distributed computing, physiology and detector modelling, computer algorithms for image reconstruction and measurement in tomography applications, for both clinical and biomedical research applications. All topics are presented with didactical language and style, making this book an appropriate reference for students and professionals seeking a comprehen...

  2. NATO Advanced Study Institute and Séminaire de mathématiques supérieures on Fractal Geometry and Analysis

    CERN Document Server

    Dubuc, Serge

    1991-01-01

    This ASI- which was also the 28th session of the Seminaire de mathematiques superieures of the Universite de Montreal - was devoted to Fractal Geometry and Analysis. The present volume is the fruit of the work of this Advanced Study Institute. We were fortunate to have with us Prof. Benoit Mandelbrot - the creator of numerous concepts in Fractal Geometry - who gave a series of lectures on multifractals, iteration of analytic functions, and various kinds of fractal stochastic processes. Different foundational contributions for Fractal Geometry like measure theory, dy­ namical systems, iteration theory, branching processes are recognized. The geometry of fractal sets and the analytical tools used to investigate them provide a unifying theme of this book. The main topics that are covered are then as follows. Dimension Theory. Many definitions of fractional dimension have been proposed, all of which coincide on "regular" objects, but often take different values for a given fractal set. There is ample discussion ...

  3. The Future of NATO Enlargement

    Science.gov (United States)

    1998-01-01

    Baltic states, Estoma , Latvia and Llthuama, as well as Albania and states of the former Yugoslatla are also generally consldered to be part of...Rornama, Slovema. Slovakia, Bulgaria. Macedoma Albania, Estoma , Latvia and Llthuama) decided to participate. The exceptions were the three states...reforms. Estoma 1s already a strong candidate for NATO member&up Latvia and Lrthuama are havmg greater drfficulties in implementing reforms, but then

  4. Integration of advanced oxidation technologies and biological processes: recent developments, trends, and advances.

    Science.gov (United States)

    Tabrizi, Gelareh Bankian; Mehrvar, Mehrab

    2004-01-01

    The greatest challenge of today's wastewater treatment technology is to optimize the use of biological and chemical wastewater treatment processes. The choice of the process and/or integration of the processes depend strongly on the wastewater characteristics, concentrations, and the desired efficiencies. It has been observed by many investigators that the coupling of a bioreactor and advanced oxidation processes (AOPs) could reduce the final concentrations of the effluent to the desired values. However, optimizing the total cost of the treatment is a challenge, as AOPs are much more expensive than biological processes alone. Therefore, an appropriate design should not only consider the ability of this coupling to reduce the concentration of organic pollutants, but also try to obtain the desired results in a cost effective process. To consider the total cost of the treatment, the residence time in biological and photochemical reactors, the kinetic rates, and the capital and operating costs of the reactors play significant roles. In this study, recent developments and trends (1996-2003) on the integration of photochemical and biological processes for the degradation of problematic pollutants in wastewater have been reviewed. The conditions to get the optimum results from this integration have also been considered. In most of the studies, it has been shown that the integrated processes were more efficient than individual processes. However, slight changes in the configuration of the reactors, temperature, pH, treatment time, concentration of the oxidants, and microorganism's colonies could lead to a great deviation in results. It has also been demonstrated that the treatment cost in both reactors is a function of time, which changes by the flow rate. The minimum cost in the coupling of the processes cannot be achieved unless considering the best treatment time in chemical and biological reactors individually.

  5. Low cost biological lung volume reduction therapy for advanced emphysema

    Directory of Open Access Journals (Sweden)

    Bakeer M

    2016-08-01

    Full Text Available Mostafa Bakeer,1 Taha Taha Abdelgawad,1 Raed El-Metwaly,1 Ahmed El-Morsi,1 Mohammad Khairy El-Badrawy,1 Solafa El-Sharawy2 1Chest Medicine Department, 2Clinical Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt Background: Bronchoscopic lung volume reduction (BLVR, using biological agents, is one of the new alternatives to lung volume reduction surgery.Objectives: To evaluate efficacy and safety of biological BLVR using low cost agents including autologous blood and fibrin glue.Methods: Enrolled patients were divided into two groups: group A (seven patients in which autologous blood was used and group B (eight patients in which fibrin glue was used. The agents were injected through a triple lumen balloon catheter via fiberoptic bronchoscope. Changes in high resolution computerized tomography (HRCT volumetry, pulmonary function tests, symptoms, and exercise capacity were evaluated at 12 weeks postprocedure as well as for complications.Results: In group A, at 12 weeks postprocedure, there was significant improvement in the mean value of HRCT volumetry and residual volume/total lung capacity (% predicted (P-value: <0.001 and 0.038, respectively. In group B, there was significant improvement in the mean value of HRCT volumetry and (residual volume/total lung capacity % predicted (P-value: 0.005 and 0.004, respectively. All patients tolerated the procedure with no mortality.Conclusion: BLVR using autologous blood and locally prepared fibrin glue is a promising method for therapy of advanced emphysema in term of efficacy, safety as well as cost effectiveness. Keywords: BLVR, bronchoscopy, COPD, interventional pulmonology

  6. Symposium by NATO Defense Research Group Panel VIII on Computer-Based Instruction in Military Environments

    CERN Document Server

    Weddle, Peter

    1987-01-01

    This collection of papers is the result of a symposium sponsored by NATO's Defense Research Group Panel VIII in the Spring of 1985. The symposium came into being when it became obvious to the NATO countries that research, development and utilization of advanced technologies for training was the best means of increasing both training effectiveness and efficiency. This symposium was the second in a series of three devoted to training. The series was structured to cover all aspects of training. The first series addressed the value of training, the second one dealt with the application of training technologies and the third and last of the series focused on academic issues concerned with the effect of prior learning on subsequent learning. The fact that a major American publisher has determined that computer based instruction is the technology of greatest interest to the NATO community is not surprising. Advances in microprocessor technology have revolutionized both how and where we train. During this symposium t...

  7. NATO laienemine peab jätkuma / Jaak Aaviksoo

    Index Scriptorium Estoniae

    Aaviksoo, Jaak, 1954-

    2008-01-01

    Albaania ja Horvaatia kirjutasid alla NATO liitumisprotokollidele. Kaitseminister tõstab esile nende pingutusi liitumiseks NATO-ga ning nende panust Afganistanis ning leiab, et NATO ja küllap tulevikus ka EL-i laienemisega Balkanile täidame oma auvõla. NATO laienemisest

  8. Rice targets Lukashenko during NATO meeting in Vilnius / Milda Seputyte

    Index Scriptorium Estoniae

    Seputyte, Milda

    2005-01-01

    Ameerika Ühendriikide välisminister Condoleezza Rice kritiseeris NATO tippkohtumisel Valgevene presidenti Aleksandr Lukashenkot, nimetades tema režiimi Euroopa viimaseks diktatuuriks. NATO tippkohtumisest Leedus. Lisad: NATO foorumi kultuuriline programm; NATO peasekretär Jaap de Hoop Scheffer

  9. Rationalizing NATO’s Defense Posture

    Science.gov (United States)

    1975-03-01

    in a capability bos — they appear too anil ’or a long SATO war and too hig (in t«ma of their demanda upon reaouroea) for a ahor* NATO war...forum for politi- cal consultation, the expansion of NATO’s role into a variety of scientific, economic, social , environmental, and even cultural

  10. Nato enlarging into the Baltic States

    Index Scriptorium Estoniae

    2003-01-01

    Prahas 21.-22. novembrini 2002 toimunud NATO tippkohtumisest ja seal vastu võetud otsusest Balti riikide alliansiga ühinemise kohta. Vt. samas: Russia's attitude to the NATO enlargement; Bush in Vilnius; Baltic states' prime ministers' met; Supporting USA?

  11. NATO dlja vnutrennogo upotreblenija / Jevgenija Garanzha

    Index Scriptorium Estoniae

    Garanža, Jevgenija, 1979-

    2004-01-01

    Tallinnas toimunud rahvusvahelisest konverentsist "Eesti - NATO liige", kus mitmed ettekandjad rõhutasid mõtet, et Kremli rahulolematus Euroopa Liidu ja NATO liikmetega on suunatud põhiliselt siseriiklikuks kasutamiseks. Venemaa hinnang oma sise- ja välispoliitilistele ohtudele

  12. Advances in the cellular and molecular biology of angiogenesis.

    Science.gov (United States)

    Egginton, Stuart; Bicknell, Roy

    2011-12-01

    Capillaries have been recognized for over a century as one of the most important components in regulating tissue oxygen transport, and their formation or angiogenesis a pivotal element of tissue remodelling during development and adaptation. Clinical interest stems from observations that both excessive and inadequate vascular growth plays a major role in human diseases, and novel developments in treatments for cancer and eye disease increasingly rely on anti-angiogenic therapies. Although the discovery of VEGF (vascular endothelial growth factor) provided the first clue for specificity of signalling in endothelial cell activation, understanding the integrative response that drives angiogenesis requires a much broader perspective. The Advances in the Cellular and Molecular Biology of Angiogenesis meeting brought together researchers at the forefront of this rapidly moving field to provide an update on current understanding, and the most recent insights into molecular and cellular mechanisms of vascular growth. The plenary lecture highlighted the integrative nature of the angiogenic process, whereas invited contributions from basic and clinician scientists described fundamental mechanisms and disease-associated issues of blood vessel formation, grouped under a number of themes to aid discussion. These articles will appeal to academic, clinical and pharmaceutical scientists interested in the molecular and cellular basis of angiogenesis, their modulation or dysfunction in human diseases, and application of these findings towards translational medicine.

  13. Immobilization biological activated carbon used in advanced drinking water treatment

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Bacteria separated from a mature filter bed of groundwater treatment plants were incubated in a culture media containing iron and manganese. A consortium of 5 strains of bacteria removing iron and manganese were obtained by repeated enrichment culturing. It was shown from the experiments of effect factors that ironmanganese removal bacteria in the culture media containing both Fe and Mn grew better than in that containing only Fe, however, they were unable to grow in the culture media containing only Mn. When comparing the bacteria biomass in the case ofρ (DO) =2.8 mg/L andρ (DO) =9.0 mg/L, no significant difference was found.The engineering bacteria removing the organic and the bacteria removing iron and manganese were simultaneously inoculated into activated carbon reactor to treat the effluent of distribution network. The experimental results showed that by using IBAC ( Immobilization Biological Activated Carbon) treatment, the removal efficiency of iron, manganese and permanganate index was more than 98% , 96% and 55% , respectively. After the influent with turbidity of 1.5 NTU, color of 25 degree and offensive odor was treated, the turbidity and color of effluence were less than 0.5 NTU and 15 degree, respectively, and it was odorless. It is determined that the cooperation function of engineering bacteria and activated carbon achieved advanced drinking water treatment.

  14. NATO-3C/Delta launch

    Science.gov (United States)

    1978-01-01

    NATO-3C, the third in a series of NATO defense-related communication satellites, is scheduled to be launched on a delta vehicle from the Eastern Test Range no earlier than November 15, 1978. NATO-3A and -3B were successfully launched by Delta vehicles in April 1976 and January 1977, respectively. The NATO-3C spacecraft will be capable of transmitting voice, data, facsimile, and telex messages among military ground stations. The launch vehicle for the NATO-3C mission will be the Delta 2914 configuration. The launch vehicle is to place the spacecraft in a synchronous transfer orbit. The spacecraft Apogee Kick motor is to be fired at fifth transfer orbit apogee to circularize its orbit at geosynchronous altitude of 35,900 km(22,260 miles) above the equator over the Atlantic Ocean somewhere between 45 and 50 degrees W longitude.

  15. Ukraine crisis deeply influences NATO's future development

    Institute of Scientific and Technical Information of China (English)

    秦朗

    2014-01-01

    The ongoing Ukraine crisis is believed to be the most significant geopolitical incident after the fall of Berlin Wall.It deeply influences,among others,the future development of NATO (North Atlantic Treaty Organization),which is the world's largest military alliance and western countries'ace in the hole in case of security emergency.The crisis enhances the status and influence of NATO on the international arena,as well as impacts NATO's transition process since the end of Cold War.The old question of Where will NATO go again becomes a hot topic.%The ongoing Ukraine crisis is believed to be the most significant geopolitical incident after the fall of Berlin Wall.It deeply influences,among others,the future development of NATO (North Atlantic Treaty Organization),which is the world's largest military alliance and western countries'ace in the hole in case of security emergency.The crisis enhances the status and influence of NATO on the international arena,as well as impacts NATO's transition process since the end of Cold War.The old question of Where will NATO go again becomes a hot topic.

  16. Terras: NATO õppuste roll Euroopas kasvab

    Index Scriptorium Estoniae

    2013-01-01

    Kaitseväe juhataja kindralmajor Riho Terrase sõnul suureneb lähiaastatel NATO õppuste roll Euroopas, sest Afganistanis sõdides saadud kogemust on vaja säilitada ning kasutada seda kollektiivkaitse tugevdamiseks

  17. Advancing cell biology through proteomics in space and time (PROSPECTS)

    DEFF Research Database (Denmark)

    Lamond, A.I.; Uhlen, M.; Horning, S.

    2012-01-01

    a range of sensitive and quantitative approaches for measuring protein structures and dynamics that promise to revolutionize our understanding of cell biology and molecular mechanisms in both human cells and model organisms. The Proteomics Specification in Time and Space (PROSPECTS) Network is a unique EU...... the proteomics field is moving beyond simply identifying proteins with high sensitivity toward providing a powerful and versatile set of assay systems for characterizing proteome dynamics and thereby creating a new "third generation" proteomics strategy that offers an indispensible tool for cell biology...... and molecular medicine. © 2012 by The American Society for Biochemistry and Molecular Biology, Inc....

  18. NATO Command Structure: Considerations for the Future

    Science.gov (United States)

    2010-09-01

    Learned Center3 3JALLC in Monsanto , Portugal Estimated ACT Strength: 1265* NATO Maritime Interdiction Operational Training Center5 5 NMIOTC at Souda...NATO to national funding. Second, the Joint Analysis and Lessons Learned Center (JALLC) in Monsanto could be brought back to ACT in Virginia or (as...Center1 Joint Warfare Center1 Joint Analysis and Lessons Learned Center2 2JALLC relocated from Monsanto , Portugal to ACT in Norfolk, VA to improve

  19. A NATO exercise on radiological sampling.

    Science.gov (United States)

    Haslip, Dean S; Mercier, J R

    2004-11-01

    The North Atlantic Treaty Organization (NATO) has held its first-ever large-scale radiological exercise employing unsealed radioactive sources. The objective of the exercise was to validate NATO protocols on radiological sampling and surveying. However, the exercise also proved to be a valuable training opportunity and was highly instructive to all involved. This paper highlights the lessons learned from this exercise, particularly in the areas of radiation survey equipment and techniques, sampling techniques, and field measurements.

  20. Systems-Level Synthetic Biology for Advanced Biofuel Production

    Energy Technology Data Exchange (ETDEWEB)

    Ruffing, Anne [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jensen, Travis J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Strickland, Lucas Marshall [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Meserole, Stephen [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Tallant, David [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-03-01

    Cyanobacteria have been shown to be capable of producing a variety of advanced biofuels; however, product yields remain well below those necessary for large scale production. New genetic tools and high throughput metabolic engineering techniques are needed to optimize cyanobacterial metabolisms for enhanced biofuel production. Towards this goal, this project advances the development of a multiple promoter replacement technique for systems-level optimization of gene expression in a model cyanobacterial host: Synechococcus sp. PCC 7002. To realize this multiple-target approach, key capabilities were developed, including a high throughput detection method for advanced biofuels, enhanced transformation efficiency, and genetic tools for Synechococcus sp. PCC 7002. Moreover, several additional obstacles were identified for realization of this multiple promoter replacement technique. The techniques and tools developed in this project will help to enable future efforts in the advancement of cyanobacterial biofuels.

  1. Development of NATO's recognized environmental picture

    Science.gov (United States)

    Teufert, John F.; Trabelsi, Mourad

    2006-05-01

    An important element for the fielding of a viable, effective NATO Response Force (NRF) is access to meteorological, oceanographic, geospatial data (GEOMETOC) and imagery. Currently, the available GEOMETOC information suffers from being very fragmented. NATO defines the Recognised Environmental Picture as controlled information base for GEOMETOC data. The NATO REP proposes an architecture that is both flexible and open. The focus lies on enabling a network-centric approach. The key into achieving this is relying on using open, well recognized standards that apply to both the data exchange protocols and the data formats. Communication and information exchange based on open standards enables system interoperability. Diverse systems, each with unique, specialized contributions to an increased understanding of the battlespace, can now cooperate to a manageable information sphere. By clearly defining responsibilities in the generation of information, a reduction in data transfer overhead is achieved . REP identifies three main stages in the dissemination of GEOMETOC data. These are Collection, Fusion (and Analysis) and Publication. A REP architecture has been successfully deployed during the NATO Coalition Warrior Interoperability Demonstration (CWID) in Lillehammer, Norway during June 2005. CWID is an annual event to validate and improve the interoperability of NATO and national Consultation and command, control, communications, computers, intelligence, surveillance, and reconnaissance (C4ISR) systems. With a test case success rate of 84%, it was able to provide relevant GEOMETOC support to the main NRF component headquarters. In 2006, the REP architecture will be deployed and validated during the NATO NRF Steadfast live exercises.

  2. Next Generation Risk Assessment: Incorporation of Recent Advances in Molecular, Computational, and Systems Biology (Final Report)

    Science.gov (United States)

    EPA announced the release of the final report, Next Generation Risk Assessment: Incorporation of Recent Advances in Molecular, Computational, and Systems Biology. This report describes new approaches that are faster, less resource intensive, and more robust that can help ...

  3. [Recent biological and therapeutic advances in multiple myeloma].

    Science.gov (United States)

    Coppetelli, U; Avvisati, G; Tribalto, M; Cantonetti, M; La Verde, G; Petrucci, T; Stasi, R; Papa, G

    1992-09-01

    Multiple myeloma still remains a fatal disease. However, in the last months new biological and clinical informations have been provided about this disease. In particular, the immunophenotype of myeloma cells seems indicate, in some patients, a clonal involvement of a stem cell in the pathogenesis of mieloma. Moreover, new biological insights concerning the cytokine network, have revealed a probable effect of some cytokines, such as IL6, IL3, IL4. Finally, new insights in the biology of multiple myeloma have been provided by studies of molecular biology and flow cytometry. As for therapy, the best conventional induction treatment still remains to be defined. In the last years, the increased use of alpha Interferon and new therapeutic modalities, such as transplantation procedures in multiple myeloma, open new hopes toward a cure of this disease. Therefore, in the future a better knowledge of the multiple myeloma biology, associated with a wider use of new effective therapeutic approaches will certainly improve the natural course of this disease.

  4. Külas on NATO peasekretär

    Index Scriptorium Estoniae

    2012-01-01

    Balti riikides visiidil olev NATO peasekretär Anders Fogh Rasmussen külastas NATO küberkaitsekeskust ja tunnustas Eesti panust kaitseorganisatsiooni kübervõimekusse. Rasmussen pidas ka avaliku loengu Tallinna Ülikoolis

  5. Wikileaks kinnitas NATO otsust teha Baltimaadele kaitsekavad / Evelyn Kaldoja

    Index Scriptorium Estoniae

    Kaldoja, Evelyn, 1980-

    2010-01-01

    Wikileaksi avalikustatud saladokumentidest sai teatavaks, et NATO kiitis heaks varem Poola kaitseks mõeldud Eagle Guardiani nimelise plaani laiendamise Eestile, Lätile ja Leedule. NATO ja Venemaa reageeringutest

  6. NATO pärast Riia-tippkohtumist / Victoria Punga

    Index Scriptorium Estoniae

    Punga, Victoria, 1977-

    2007-01-01

    Eesti NATO ühingu 3. veebruaril toimunud üldkogul olid arutluse all kolm suuremat teemaderingi: NATO tegevus ja operatsioonid Afganistanis, alliansi edasine laienemine ning Riias peetud tippkohtumise poliitiline sõnum

  7. NATO chief arrives to discuss alliance's new strategy / Ella Karapetyan

    Index Scriptorium Estoniae

    Karapetyan, Ella

    2009-01-01

    8. oktoobril Eestis visiidil viibinud NATO peasekretär Anders Fogh Rasmussen kohtus president Toomas Hendrik Ilvese ja välisminister Urmas Paetiga. Teemadeks oli Afganistanis toimuv, NATO ja viimase suhted Venemaaga

  8. NATO Planning Guide for the Estimation of Chemical, Biological, Radiological, and Nuclear (CBRN) Casualties (AMedP-8(C)) - Parameters for Estimation of Casualties from Exposure to Specified Biological Agents. Addenda to Allied Medical Publication 8

    Science.gov (United States)

    2011-01-01

    estimating the numbers of persons developing illness or dying from anthrax, botulism, Venezuelan equine encephalitis, plague, and smallpox. Five additional...the non-contagious biological agent explanation in Section 0106.7b, following the Venezuelan equine encephalitis (VEE) assumptions and limitations...comprehensive clinical studies of tularemia available were reported in the pre- antibiotic era before inhalation was understood to be a potential route of

  9. Advances in isothermal amplification: novel strategies inspired by biological processes.

    Science.gov (United States)

    Li, Jia; Macdonald, Joanne

    2015-02-15

    Nucleic acid amplification is an essential process in biological systems. The in vitro adoption of this process has resulted in powerful techniques that underpin modern molecular biology. The most common tool is polymerase chain reaction (PCR). However, the requirement for a thermal cycler has somewhat limited applications of this classic nucleic acid amplification technique. Isothermal amplification, on the other hand, obviates the use of a thermal cycler because reactions occur at a single temperature. Isothermal amplification methods are diverse, but all have been developed from an understanding of natural nucleic acid amplification processes. Here we review current isothermal amplification methods as classified by their enzymatic mechanisms. We compare their advantages, disadvantages, efficiencies, and applications. Finally, we mention some new developments associated with this technology, and consider future possibilities in molecular engineering and recombinant technologies that may develop from an appreciation of the molecular biology of natural systems.

  10. Chemical Biology Probes from Advanced DNA-encoded Libraries.

    Science.gov (United States)

    Salamon, Hazem; Klika Škopić, Mateja; Jung, Kathrin; Bugain, Olivia; Brunschweiger, Andreas

    2016-02-19

    The identification of bioactive compounds is a crucial step toward development of probes for chemical biology studies. Screening of DNA-encoded small molecule libraries (DELs) has emerged as a validated technology to interrogate vast chemical space. DELs consist of chimeric molecules composed of a low-molecular weight compound that is conjugated to a DNA identifier tag. They are screened as pooled libraries using selection to identify "hits." Screening of DELs has identified numerous bioactive compounds. Some of these molecules were instrumental in gaining a deeper understanding of biological systems. One of the main challenges in the field is the development of synthesis methodology for DELs.

  11. Advanced treatment of biologically pretreated coal gasification wastewater by a novel integration of heterogeneous catalytic ozonation and biological process.

    Science.gov (United States)

    Zhuang, Haifeng; Han, Hongjun; Jia, Shengyong; Hou, Baolin; Zhao, Qian

    2014-08-01

    Advanced treatment of biologically pretreated coal gasification wastewater (CGW) was investigated employing heterogeneous catalytic ozonation integrated with anoxic moving bed biofilm reactor (ANMBBR) and biological aerated filter (BAF) process. The results indicated that catalytic ozonation with the prepared catalyst (i.e. MnOx/SBAC, sewage sludge was converted into sludge based activated carbon (SBAC) which loaded manganese oxides) significantly enhanced performance of pollutants removal by generated hydroxyl radicals. The effluent of catalytic ozonation process was more biodegradable and less toxic than that in ozonation alone. Meanwhile, ANMBBR-BAF showed efficient capacity of pollutants removal in treatment of the effluent of catalytic ozonation at a shorter reaction time, allowing the discharge limits to be met. Therefore, the integrated process with efficient, economical and sustainable advantages was suitable for advanced treatment of real biologically pretreated CGW.

  12. 22 CFR 120.32 - Major non-NATO ally.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Major non-NATO ally. 120.32 Section 120.32... § 120.32 Major non-NATO ally. Major non-NATO ally means a country that is designated in accordance with § 517 of the Foreign Assistance Act of 1961 (22 U.S.C. 2321k) as a major non-NATO ally for purposes...

  13. Advances and Computational Tools towards Predictable Design in Biological Engineering

    Directory of Open Access Journals (Sweden)

    Lorenzo Pasotti

    2014-01-01

    Full Text Available The design process of complex systems in all the fields of engineering requires a set of quantitatively characterized components and a method to predict the output of systems composed by such elements. This strategy relies on the modularity of the used components or the prediction of their context-dependent behaviour, when parts functioning depends on the specific context. Mathematical models usually support the whole process by guiding the selection of parts and by predicting the output of interconnected systems. Such bottom-up design process cannot be trivially adopted for biological systems engineering, since parts function is hard to predict when components are reused in different contexts. This issue and the intrinsic complexity of living systems limit the capability of synthetic biologists to predict the quantitative behaviour of biological systems. The high potential of synthetic biology strongly depends on the capability of mastering this issue. This review discusses the predictability issues of basic biological parts (promoters, ribosome binding sites, coding sequences, transcriptional terminators, and plasmids when used to engineer simple and complex gene expression systems in Escherichia coli. A comparison between bottom-up and trial-and-error approaches is performed for all the discussed elements and mathematical models supporting the prediction of parts behaviour are illustrated.

  14. Recent advances in the chemistry and biology of pyridopyrimidines.

    Science.gov (United States)

    Buron, F; Mérour, J Y; Akssira, M; Guillaumet, G; Routier, S

    2015-05-05

    The interest in pyridopyrimidine cores for pharmaceutical products makes this scaffold a highly useful building block for organic chemistry. These derivatives have found applications in various areas of medicine such as anticancer, CNS, fungicidal, antiviral, anti-inflammatory, antimicrobial, and antibacterial therapies. This review mainly focuses on the progress achieved since 2004 in the chemistry and biological activity of pyridopyrimidines.

  15. Advances in Biological Water-saving Research: Challenge and Perspectives

    Institute of Scientific and Technical Information of China (English)

    Lun Shan; Xiping Deng; Suiqi Zhang

    2006-01-01

    Increasing the efficiency of water use by crops continues to escalate as a topic of concern because drought is a restrictive environmental factor for crop productivity worldwide. Greater yield per unit rainfall is one of the most important challenges in water-saving agriculture. Besides water-saving by irrigation engineering and conservation tillage, a good understanding of factors limiting and/or regulating yield now provides us with an opportunity to identify and then precisely select for physiological and breeding traits that increase the efficiency of water use and drought tolerance under water-limited conditions, biological water-saving is one means of achieving this goat. A definition of biological water-saving measures is proposed which embraces improvements in water-use efficiency (WUE) and drought tolerance, by genetic improvement and physiological regulation. The preponderance of biological water-saving measures is discussed and strategies identified for working within natural resource constraints. The technology and future perspectives of biological water saving could provide not only new water-saving techniques but also a scientific base for application of water-saving irrigation and conservation tillage.

  16. Are ISO Terminology Standards Fit for Terminology Management at the NATO?

    OpenAIRE

    Steurs, Frieda; Kockaert, Hendrik

    2015-01-01

    NATO Conference on Terminology Management 19-20 November 2015 Are ISO Terminology Standards Fit for Terminology Management at the NATO? Hendrik J. Kockaert1,2 & Frieda Steurs1,2,3 KU Leuven1, University of the Free State2, UCO3 Abstract The NATO Terminology Office (NTO) advocates clear and unambiguous communication among its members and partners, following the NATO Policy for Standardization: "NATO documents must contain NATO agreed terminology." It is the NATO Termino...

  17. Is the North Atlantic Treaty Organization (NATO) Sustainable?

    Science.gov (United States)

    2012-03-22

    II, and the Soviet Union tested its first nuclear device in October 1949.23 Through NATO, during the Cold War and beyond, NATO member-states were...Ibid. 5 Ibid. 6 Zoltan Barany , The Future of NATO Expansion: Four Case Studies (New York: Cambridge University Press, 2003), 2. 7 Rachwald, “A

  18. NATO enlargement : all aboard? Destination unknown / Richard E Rupp

    Index Scriptorium Estoniae

    Rupp, Richard E

    2002-01-01

    NATO eesmärkidest läbi aegade, külma sõja järgse üleminekuaja mõjudest NATO arengule, laienemisega seonduvast temaatikast lähtuvalt Leedu, Rumeenia ja Venemaa seisukohtadest ning NATO tulevikuväljavaadetest

  19. NATO in History and Civics Textbooks: The West German Case.

    Science.gov (United States)

    Fritzsche, K. Peter

    1990-01-01

    When analyzing the degree to which a balanced presentation of NATO is achieved in West German history and civics textbooks, two standards may be used: first, inclusion of information on NATO's formation, aims, strategies and achievements; and, second, inclusion of the criticisms that have been leveled at NATO from various points of view. This…

  20. Teaching American Diplomacy Using Primary Sources. The Expansion of NATO.

    Science.gov (United States)

    Miles, Michael; Schuster, Heidi

    In this high school U.S. government and U.S. history curriculum unit, students examine in depth the expansion of the North Atlantic Treaty Organization (NATO). Detailed activities are provided to teach students about the origins of NATO, its impact on U.S. foreign policy, and its future directions, particularly the enlargement of NATO in the…

  1. Advances in the biological effects of terahertz wave radiation.

    Science.gov (United States)

    Zhao, Li; Hao, Yan-Hui; Peng, Rui-Yun

    2014-01-01

    The terahertz (THz) band lies between microwave and infrared rays in wavelength and consists of non-ionizing radiation. Both domestic and foreign research institutions, including the army, have attached considerable importance to the research and development of THz technology because this radiation exhibits both photon-like and electron-like properties, which grant it considerable application value and potential. With the rapid development of THz technology and related applications, studies of the biological effects of THz radiation have become a major focus in the field of life sciences. Research in this field has only just begun, both at home and abroad. In this paper, research progress with respect to THz radiation, including its biological effects, mechanisms and methods of protection, will be reviewed.

  2. Recent advances in the cell biology of polycystic kidney disease.

    Science.gov (United States)

    Smyth, Brendan J; Snyder, Richard W; Balkovetz, Daniel F; Lipschutz, Joshua H

    2003-01-01

    Autosomal dominant polycystic kidney disease (ADPKD) is a significant familial disorder, crossing multiple ethnicities as well as organ systems. The goal of understanding and, ultimately, curing ADPKD has fostered collaborative efforts among many laboratories, mustered on by the opportunity to probe fundamental cellular biology. Here we review what is known about ADPKD including well-accepted data such as the identification of the causative genes and the fact that PKD1 and PKD2 act in the same pathway, fairly well-accepted concepts such as the "two-hit hypothesis," and somewhat confusing information regarding polycystin-1 and -2 localization and protein interactions. Special attention is paid to the recently discovered role of the cilium in polycystic kidney disease and the model it suggests. Studying ADPKD is important, not only as an evaluation of a multisystem disorder that spans a lifetime, but as a testament to the achievements of modern biology and medicine.

  3. Advances in the biological effects of terahertz wave radiation

    Institute of Scientific and Technical Information of China (English)

    Li Zhao; Yan-Hui Hao; Rui-Yun Peng

    2014-01-01

    The terahertz (THz) band lies between microwave and infrared rays in wavelength and consists of non-ionizing radiation. Both domestic and foreign research institutions, including the army, have attached considerable importance to the research and development of THz technology because this radiation exhibits both photon-like and electron-like properties, which grant it considerable application value and potential. With the rapid development of THz technology and related applications, studies of the biological effects of THz radiation have become a major focus in the field of life sciences. Research in this field has only just begun, both at home and abroad. In this paper, research progress with respect to THz radiation, including its biological effects, mechanisms and methods of protection, will be reviewed.

  4. Nanotechnological Basis for Advanced Sensors

    CERN Document Server

    Reithmaier, Johann Peter; Kulisch, Wilhelm; Popov, Cyril; Petkov, Plamen

    2011-01-01

    Bringing together experts from 15 countries, this book is based on the lectures and contributions of the NATO Advanced Study Institute on “Nanotechnological Basis for Advanced Sensors” held in Sozopol, Bulgaria, 30 May - 11 June, 2010. It gives a broad overview on this topic, and includes articles on: techniques for preparation and characterization of sensor materials; different types of nanoscaled materials for sensor applications, addressing both their structure (nanoparticles, nanocomposites, nanostructured films, etc.) and chemical nature (carbon-based, oxides, glasses, etc.); and on advanced sensors that exploit nanoscience and nanotechnology. In addition, the volume represents an interdisciplinary approach with authors coming from diverse fields such as physics, chemistry, engineering, materials science and biology. A particular strength of the book is its combination of longer papers, introducing the basic knowledge on a certain topic, and brief contributions highlighting special types of sensors a...

  5. Nuclear weapons and NATO-Russia relations

    Energy Technology Data Exchange (ETDEWEB)

    Cornwell, G.C.

    1998-12-01

    Despite the development of positive institutional arrangements such as Russian participation in the NATO-led peacekeeping force in Bosnia and the NATO- Russia Permanent Joint Council, the strategic culture of Russia has not changed in any fundamental sense. Russian strategic culture has not evolved in ways that would make Russian policies compatible with those of NATO countries in the necessary economic, social, technological, and military spheres. On the domestic side, Russia has yet to establish a stable democracy and the necessary legal, judicial, and regulatory institutions for a free-market economy. Russia evidently lacks the necessary cultural traditions, including concepts of accountability and transparency, to make these adaptations in the short-term. Owing in part to its institutional shortcomings, severe socioeconomic setbacks have afflicted Russia. Russian conventional military strength has been weakened, and a concomitant reliance by the Russians on nuclear weapons as their ultimate line of defense has increased. The breakdown in the infrastructure that supports Russian early warning and surveillance systems and nuclear weapons stewardship defense, coupled with a tendency towards has exacerbated Russian anxiety and distrust toward NATO. Russia`s reliance on nuclear weapons as the ultimate line of defense, coupled with a tendency toward suspicion and distrust toward NATO, could lead to dangerous strategic miscalculation and nuclear catastrophe.

  6. The biology of infertility: research advances and clinical challenges

    Science.gov (United States)

    Matzuk, Martin M; Lamb, Dolores J

    2013-01-01

    Reproduction is required for the survival of all mammalian species, and thousands of essential ‘sex’ genes are conserved through evolution. Basic research helps to define these genes and the mechanisms responsible for the development, function and regulation of the male and female reproductive systems. However, many infertile couples continue to be labeled with the diagnosis of idiopathic infertility or given descriptive diagnoses that do not provide a cause for their defect. For other individuals with a known etiology, effective cures are lacking, although their infertility is often bypassed with assisted reproductive technologies (ART), some accompanied by safety or ethical concerns. Certainly, progress in the field of reproduction has been realized in the twenty-first century with advances in the understanding of the regulation of fertility, with the production of over 400 mutant mouse models with a reproductive phenotype and with the promise of regenerative gonadal stem cells. Indeed, the past six years have witnessed a virtual explosion in the identification of gene mutations or polymorphisms that cause or are linked to human infertility. Translation of these findings to the clinic remains slow, however, as do new methods to diagnose and treat infertile couples. Additionally, new approaches to contraception remain elusive. Nevertheless, the basic and clinical advances in the understanding of the molecular controls of reproduction are impressive and will ultimately improve patient care. PMID:18989307

  7. Recent advances in molecular biology of parasitic viruses.

    Science.gov (United States)

    Banik, Gouri Rani; Stark, Damien; Rashid, Harunor; Ellis, John T

    2014-01-01

    The numerous protozoa that can inhabit the human gastro-intestinal tract are known, yet little is understood of the viruses which infect these protozoa. The discovery, morphologic details, purification methods of virus-like particles, genome and proteome of the parasitic viruses, Entamoeba histolytica, Giardia lamblia, Trichomonas vaginalis, and the Eimeria sp. are described in this review. The protozoan viruses share many common features: most of them are RNA or double-stranded RNA viruses, ranging between 5 and 8 kilobases, and are spherical or icosahedral in shape with an average diameter of 30-40 nm. These viruses may influence the function and pathogenicity of the protozoa which they infect, and may be important to investigate from a clinical perspective. The viruses may be used as specific genetic transfection vectors for the parasites and may represent a research tool. This review provides an overview on recent advances in the field of protozoan viruses.

  8. NATO peab jääma oluliseks / Jamie Shea, Ronald Asmus ; interv. Erkki Bahovski

    Index Scriptorium Estoniae

    Shea, Jamie

    2006-01-01

    NATO peasekretäri poliitikaplaneerimise juht dr. Jamie Shea ja USA Saksa Marshalli Keskuse direktor dr. Ronald Asmus räägivad NATO uuendamise tähtsusest ja selleteemalise avaliku debati vajalikkusest. NATO Riia tippkohtumise ülesandest, Eesti uutest väljakutsetest NATO-s

  9. Can the natural diversity of quorum sensing advance synthetic biology?

    Directory of Open Access Journals (Sweden)

    Rene Michele Davis

    2015-03-01

    Full Text Available Quorum-sensing networks enable bacteria to sense and respond to chemical signals produced by neighboring bacteria. They are widespread: over one hundred morphologically and genetically distinct species of eubacteria are known to use quorum sensing to control gene expression. This diversity suggests the potential to use natural protein variants to engineer parallel, input-specific, cell-cell communication pathways. However, only three distinct signaling pathways, Lux, Las, and Rhl, have been adapted for and broadly used in engineered systems. The paucity of unique quorum-sensing systems and their propensity for crosstalk limits the usefulness of our current quorum-sensing toolkit. This review discusses the need for more signaling pathways, roadblocks to using multiple pathways in parallel, and strategies for expanding the quorum-sensing toolbox for synthetic biology.

  10. Biology and Industrial Applications of Chlorella: Advances and Prospects.

    Science.gov (United States)

    Liu, Jin; Chen, Feng

    2016-01-01

    Chlorella represents a group of eukaryotic green microalgae that has been receiving increasing scientific and commercial interest. It possesses high photosynthetic ability and is capable of growing robustly under mixotrophic and heterotrophic conditions as well. Chlorella has long been considered as a source of protein and is now industrially produced for human food and animal feed. Chlorella is also rich in oil, an ideal feedstock for biofuels. The exploration of biofuel production by Chlorella is underway. Chlorella has the ability to fix carbon dioxide efficiently and to remove nutrients of nitrogen and phosphorous, making it a good candidate for greenhouse gas biomitigation and wastewater bioremediation. In addition, Chlorella shows potential as an alternative expression host for recombinant protein production, though challenges remain to be addressed. Currently, omics analyses of certain Chlorella strains are being performed, which will help to unravel the biological implications of Chlorella and facilitate the future exploration of industrial applications.

  11. Emerging issues and methodological advances in fisheries reproductive biology

    DEFF Research Database (Denmark)

    Lowerre-Barbieri, Susan K.; Brown-Peterson, Nancy J.; Murua, Hilario;

    2011-01-01

    Although incorporating detailed reproductive data into all stock assessments is not a practical goal, the need to understand how reproductive biology affects population productivity is being increasingly recognized.More research focused on reproductive biology—coupled with a shift towards...... development, which is most accurately evaluated with histology. This special section of Marine and Coastal Fisheries contains contributions from a workshop on the gonadal histology of fishes that was held in Cadiz, Spain, during June 2009. These papers cover a wide range of species and reproductive topics...... a resilience perspective in fisheries science—is resulting in challenges to many long-held assumptions; the emergence of important new issues; and identification of the need to improve data and methods used in reproductive studies. Typically, data for reproductive studies are based on an assessment of gonadal...

  12. Advancing cell biology through proteomics in space and time (PROSPECTS).

    Science.gov (United States)

    Lamond, Angus I; Uhlen, Mathias; Horning, Stevan; Makarov, Alexander; Robinson, Carol V; Serrano, Luis; Hartl, F Ulrich; Baumeister, Wolfgang; Werenskiold, Anne Katrin; Andersen, Jens S; Vorm, Ole; Linial, Michal; Aebersold, Ruedi; Mann, Matthias

    2012-03-01

    The term "proteomics" encompasses the large-scale detection and analysis of proteins and their post-translational modifications. Driven by major improvements in mass spectrometric instrumentation, methodology, and data analysis, the proteomics field has burgeoned in recent years. It now provides a range of sensitive and quantitative approaches for measuring protein structures and dynamics that promise to revolutionize our understanding of cell biology and molecular mechanisms in both human cells and model organisms. The Proteomics Specification in Time and Space (PROSPECTS) Network is a unique EU-funded project that brings together leading European research groups, spanning from instrumentation to biomedicine, in a collaborative five year initiative to develop new methods and applications for the functional analysis of cellular proteins. This special issue of Molecular and Cellular Proteomics presents 16 research papers reporting major recent progress by the PROSPECTS groups, including improvements to the resolution and sensitivity of the Orbitrap family of mass spectrometers, systematic detection of proteins using highly characterized antibody collections, and new methods for absolute as well as relative quantification of protein levels. Manuscripts in this issue exemplify approaches for performing quantitative measurements of cell proteomes and for studying their dynamic responses to perturbation, both during normal cellular responses and in disease mechanisms. Here we present a perspective on how the proteomics field is moving beyond simply identifying proteins with high sensitivity toward providing a powerful and versatile set of assay systems for characterizing proteome dynamics and thereby creating a new "third generation" proteomics strategy that offers an indispensible tool for cell biology and molecular medicine.

  13. Mass spectrometric determination of early and advanced glycation in biology.

    Science.gov (United States)

    Rabbani, Naila; Ashour, Amal; Thornalley, Paul J

    2016-08-01

    Protein glycation in biological systems occurs predominantly on lysine, arginine and N-terminal residues of proteins. Major quantitative glycation adducts are found at mean extents of modification of 1-5 mol percent of proteins. These are glucose-derived fructosamine on lysine and N-terminal residues of proteins, methylglyoxal-derived hydroimidazolone on arginine residues and N(ε)-carboxymethyl-lysine residues mainly formed by the oxidative degradation of fructosamine. Total glycation adducts of different types are quantified by stable isotopic dilution analysis liquid chromatography-tandem mass spectrometry (LC-MS/MS) in multiple reaction monitoring mode. Metabolism of glycated proteins is followed by LC-MS/MS of glycation free adducts as minor components of the amino acid metabolome. Glycated proteins and sites of modification within them - amino acid residues modified by the glycating agent moiety - are identified and quantified by label-free and stable isotope labelling with amino acids in cell culture (SILAC) high resolution mass spectrometry. Sites of glycation by glucose and methylglyoxal in selected proteins are listed. Key issues in applying proteomics techniques to analysis of glycated proteins are: (i) avoiding compromise of analysis by formation, loss and relocation of glycation adducts in pre-analytic processing; (ii) specificity of immunoaffinity enrichment procedures, (iii) maximizing protein sequence coverage in mass spectrometric analysis for detection of glycation sites, and (iv) development of bioinformatics tools for prediction of protein glycation sites. Protein glycation studies have important applications in biology, ageing and translational medicine - particularly on studies of obesity, diabetes, cardiovascular disease, renal failure, neurological disorders and cancer. Mass spectrometric analysis of glycated proteins has yet to find widespread use clinically. Future use in health screening, disease diagnosis and therapeutic monitoring, and

  14. Effect-Based Thinking in NATO

    DEFF Research Database (Denmark)

    Møller, Hans Henrik

    2014-01-01

    to implement the alliance’s contribution to a comprehensive approach. Even though the “big three,” United States, Britain, and France, hold a predominant position, it is obvious by definition that an alliance cannot adopt a state-centric driven grand strategy. Quite simply, NATO has to literally negotiate...... a consensus around the common security strategy, as well as negotiate common consent to the strategy it adopts to pursue its strategic goals in theater....... in the NATO strategy, concepts, doctrines, or planning documents yet, as pointed out earlier in chapter two, it is an important holistic strategic parameter that in this case will determine the scope of NATO action—or inaction. This chapter will argue that despite its absence in the wording of doctrine...

  15. NATO at 40 Years: A Critical Assessment

    Science.gov (United States)

    1989-01-01

    Eusebio. "Rel(g~ning in Spain.’ Foreign Policy. 51 (Summer 1983): 101-117. Newman, Anthony T. Britain’s Contribution to NATO: A New perspective...106. Tucker, Robert W. , Linda Wrigley , and Theodore Draper, eds. The Atlantic Alliance and Its Critics. New York: Praeger, 183. (JX 1303 .N87 A74 1083...8217 Military Review. 65 (May 1985): 2-15. King-Harmon, Anthony L. *NATO Strategy-- A New Look.* RUSI Journal for Defence Studies. 129 (Mar. 1984): 26

  16. THE NEW STRATEGIC CONCEPT NATO 2010

    Directory of Open Access Journals (Sweden)

    Marin ILIE

    2011-01-01

    Full Text Available NATO (The North Atlantic Treaty Organization – OTAN (Organisation du Traité de l’Atlantique Nord has been, since its estabslishment, oustandingly receptive to the international security environment developments and has always altered its strategy and strategic concepts in order to meet the afferent challenges, with an emphasis on its purely defensive character. The most favorable moment of this kind have been its summits: Rome (1991, Washington (1999 and Lisbon (2010, on which our paper will focus. The greats mutations in the last decade have called for the creation of the new strategic concept NATO 2010, developed in the Lisbon summit declaration of 19-20 November 2010.

  17. Advances in detection of antipsychotics in biological matrices.

    Science.gov (United States)

    Patteet, Lisbeth; Cappelle, Delphine; Maudens, Kristof E; Crunelle, Cleo L; Sabbe, Bernard; Neels, Hugo

    2015-02-20

    Measuring antipsychotic concentrations in human matrices is important for both therapeutic drug monitoring and forensic toxicology. This review provides a critical overview of the analytical methods for detection and quantification of antipsychotics published in the last four years. Focus lies on advances in sample preparation, analytical techniques and alternative matrices. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is used most often for quantification of antipsychotics. This sensitive technique makes it possible to determine low concentrations not only in serum, plasma or whole blood, but also in alternative matrices like oral fluid, dried blood spots, hair, nails and other body tissues. Current literature on analytical techniques for alternative matrices is still limited and often requires a more thorough validation including a comparison between conventional and alternative results to determine their actual value. Ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) makes it possible to quantify a high amount of compounds within a shorter run time. This technique is widely used for multi-analyte methods. Only recently, high-resolution mass spectrometry has gained importance when a combination of screening of (un)known metabolites, and quantification is required.

  18. Improving human forensics through advances in genetics, genomics and molecular biology.

    Science.gov (United States)

    Kayser, Manfred; de Knijff, Peter

    2011-03-01

    Forensic DNA profiling currently allows the identification of persons already known to investigating authorities. Recent advances have produced new types of genetic markers with the potential to overcome some important limitations of current DNA profiling methods. Moreover, other developments are enabling completely new kinds of forensically relevant information to be extracted from biological samples. These include new molecular approaches for finding individuals previously unknown to investigators, and new molecular methods to support links between forensic sample donors and criminal acts. Such advances in genetics, genomics and molecular biology are likely to improve human forensic case work in the near future.

  19. Biology and biotechnological advances in Jatropha curcas - A biodiesel plant

    KAUST Repository

    Reddy, Muppala P.

    2009-10-31

    Increasing global demand for energy, the impending depletion of fossil fuels, and concern over global climate change have lead to a resurgence in the development of alternative energy sources. Bio-fuels and bio-energy encompass a wide range of alternative sources of energy of biological origin, and offer excellent, environmentally friendly opportunities to address these issues. The recognition that Jatropha oil can yield high quality biodiesel has led to a surge of interest in Jatropha across the globe, more so in view of the potential for avoiding the dilemma of food vs fuel. Hardiness, rapid growth, easy propagation, short gestation period, wide adaptation, and optimum plant size combine to make this species suitable for sustainable cultivation on wastelands. Besides biodiesel from the seed, the plant produces several useful products that also have commercial value. Large scale cultivation remains the single most important factor that will ultimately determine the success of Jatropha as a source of bio-fuel. The limited knowledge of the genetics of this species, low and inconsistent yields, the narrow genetic variability, and vulnerability to insects and diseases are major constraints in successful cultivation of Jatropha as a bio-fuel crop. Despite the optimal protein content and composition of the pressed cake, the presence of phorbol esters makes it unsuitable for consumption by livestock. A non-toxic variety with low or no phorbol ester content has been identified from Mexico, and the utility of pressed cake from this variety as livestock feed has been demonstrated successfully. In the absence of any morphological differences, identification of linked markers for toxic/non-toxic varieties will add value to the crop and facilitate further improvement. This chapter discusses current efforts towards assessing the diversity and phylogeny of Jatropha, identification of specific markers for toxic and non-toxic varieties, and aspects of micropropagation and genetic

  20. Recent advances in operations research in computational biology, bioinformatics and medicine

    OpenAIRE

    Türkay, Metin; Felici, Giovanni; Szachniuk, Marta; Lukasiak, Piotr

    2014-01-01

    The EURO Working Group on Operations Research in Computational Biology, Bioinformatics and Medicine held its fourth conference in Poznan-Biedrusko, Poland, June 26-28, 2014. The editorial board of RAIRO-OR invited submissions of papers to a special issue on Recent Advances in Operations Research in Computational Biology, Bioinformatics and Medicine. This special issue includes nine papers that were selected among forty presentations and included in this special issue after two rounds of revie...

  1. Advanced Sensors for Safety and Security

    CERN Document Server

    Khudaverdyan, Surik

    2013-01-01

    This book results from a NATO Advanced Research Workshop titled “Technological Innovations in CBRNE Sensing and Detection for Safety, Security, and Sustainability” held in Yerevan, Armenia in 2012. The objective was to discuss and exchange views as to how fusion of advanced technologies can lead to improved sensors/detectors in support of defense, security, and situational awareness. The chapters range from policy and implementation, advanced sensor platforms using stand-off (THz and optical) and point-contact methods for detection of chemical, nuclear, biological, nuclear and explosive agents and contaminants in water, to synthesis methods for several materials used for sensors.  In view of asymmetric, kinetic, and distributed nature of threat vectors, an emphasis is placed to examine new generation of sensors/detectors that utilize an ecosystems of innovation and advanced sciences convergence in support of effective counter-measures against  CBRNE threats. The book will be of considerable interest and...

  2. Information Literacy in Biology Education: An Example from an Advanced Cell Biology Course

    Science.gov (United States)

    Porter, John R.

    2005-01-01

    Information literacy skills are critically important for the undergraduate biology student. The ability to find, understand, evaluate, and use information, whether from the scientific literature or from Web resources, is essential for a good understanding of a topic and for the conduct of research. A project in which students receive information…

  3. A perfect time to harness advanced molecular technologies to explore the fundamental biology of Toxocara species.

    Science.gov (United States)

    Gasser, Robin B

    2013-04-15

    Toxocarosis is of major canine health and socioeconomic importance worldwide. Although many studies have given insights into toxocarosis, to date, there has been limited exploration of the molecular biology, biochemistry, genetics, epidemiology and ecology of Toxocara species as well as parasite-host interactions using '-omic' technologies. The present article gives a background on Toxocara species and toxocarosis, describes molecular tools for specific identification and genetic analysis, and provides a prospective view of the benefits that advanced molecular technologies will have towards better understanding the parasites and disease. Tackling key biological questions employing a 'systems biology' approach should lead to new and improved strategies for the treatment, diagnosis and control of toxocarosis.

  4. NATO peasekretär tuleb Eestisse

    Index Scriptorium Estoniae

    2014-01-01

    Sel nädalal tuleb Eestisse kahepäevasele visiidile NATO peasekretär Anders Fogh Rasmussen, kohtumistel Eesti juhtidega on kõne all muutunud julgeolekuolukord Euroopas. Reedel peab ta Tallinna Ülikoolis avaliku loengu ning külastab koos välisministriga Ämari lennubaasi

  5. The Politics of Weapons Standardization in NATO.

    Science.gov (United States)

    1981-07-01

    does raise new and useful perspectives on the problem. And, as he notes, it raises the spectre that instead of attacking the causes of NATO’s malaise...construct- ing his Utopia . 1 58 Two articles, which focus on the weapons procurement process within the United States alone, note the unnecessary

  6. Soome julgeolekupoliitika ja NATO / Jaakko Blomberg

    Index Scriptorium Estoniae

    Blomberg, Jaakko

    2003-01-01

    Soome julgeolekupoliitika pärast külma sõja lõppu. Olukorras, kus Euroopa Liit jätkab oma sõjalise tegevusvõime tugevdamist, on põhjendatud küsimus, kas Soomele piisab vaid NATO partnerlusest

  7. NATO Initiatives to Improve Life Cycle Costing

    NARCIS (Netherlands)

    Smit, M.C.

    2009-01-01

    There is a long and documented history of both cost growth and estimating optimism within military programmes. This is particularly the case for multi-national programmes. The NATO ALP-10 –Guidance on Integrated Logistics Support for multi-national equipment projects (ILS) dated June 1990 (Reference

  8. Russia and the Future Expansion of NATO

    Science.gov (United States)

    2011-03-24

    warned it could deploy its missiles in Kaliningrad to target intended missile defense sites.26 Recently, NATO expressed that it “will actively seek...lng=en&id=38752 (accessed January 21, 2011). 26 Vladimir Socor, “Russia Warns of Forward Missile Deployment in Kaliningrad Region,” Eurasia Daily

  9. NATO: Key to Success in Afghanistan

    Science.gov (United States)

    2011-03-24

    respond to the priorities of their country’s capitals and not the GIROA or ISAFneeds. This national branding of uncoordinated aid efforts ·is endemic...Reconstruction, Billions Spent, But No One Knows Just How." The New American, 29 December 2010. • Volker Kurt. "The Bucharest Summit: NATO and the Future of

  10. NATO’s Future and Relevance

    Science.gov (United States)

    2012-02-03

    is telling the truth.20 These disagreements between the U.S. and Russia may precipitate in Russian withdrawal from the New Strategic Arms Reduction...as Bulgaria, Hungary, and Romania. As 9 NATO has expanded into Poland, Hungary, the Czech Republic, Cyprus, and Malta , the alliance has looked

  11. How Allies Collaborate; The NATO Training Experience.

    Science.gov (United States)

    Vandevanter, E., Jr.

    A survey was made of North Atlantic Treaty Organization (NATO) coordination of training programs for allied military forces and its implications about collaboration among allies in peacetime. Three types of training were analyzed: (1) higher training, or the coordination of large military formations; (2) unit training of smaller teams; (3)…

  12. [Advances in studies on chemical constituents and biological activities of Desmodium species].

    Science.gov (United States)

    Liu, Chao; Wu, Ying; Zhang, Qian-Jun; Kang, Wen-Yi; Zhang, Long; Zhou, Qing-Di

    2013-12-01

    The chemical constituents isolated from Desmodium species (Leguminosae) included terpenoids, flavonoids, steroids, alkaloids compounds. Modem pharmacological studies have showed that the Desmodium species have antioxidant, antibacterial, anti-inflammatory, hepatoprotective, diuretic, antipyretic, analgesic and choleretic activity. This article mainly has reviewed the research advances of chemical constituents and biological activities of Desmodium species since 2003.

  13. Advances in the Management of Juvenile Idiopathic Arthritis : The coming of age of biologic treatment

    NARCIS (Netherlands)

    J. Anink (Janneke)

    2015-01-01

    markdownabstract__Abstract__ The main aim of this thesis was the evaluation of advances in the management of JIA. It focused on developments in the biologic treatment of JIA, using data from the ABC register. Additionally, it explored new biomarkers and methods for monitoring the disease activity,

  14. Advanced Level Biology Teachers' Attitudes towards Assessment and Their Engagement in Assessment for Learning

    Science.gov (United States)

    Bramwell-Lalor, Sharon; Rainford, Marcia

    2015-01-01

    This paper reports on a Mixed Methods study involving an investigation into the attitudes of advanced level biology teachers towards assessment and describes the teachers' experiences while being engaged in Assessment for Learning (AfL) practices such as sharing of learning objectives and peer- and self-assessment. Quantitative data were collected…

  15. Advanced treatment of biologically pretreated coal gasification wastewater by a novel integration of heterogeneous Fenton oxidation and biological process.

    Science.gov (United States)

    Xu, Peng; Han, Hongjun; Zhuang, Haifeng; Hou, Baolin; Jia, Shengyong; Xu, Chunyan; Wang, Dexin

    2015-04-01

    Laboratorial scale experiments were conducted in order to investigate a novel system integrating heterogeneous Fenton oxidation (HFO) with anoxic moving bed biofilm reactor (ANMBBR) and biological aerated filter (BAF) process on advanced treatment of biologically pretreated coal gasification wastewater (CGW). The results indicated that HFO with the prepared catalyst (FeOx/SBAC, sewage sludge based activated carbon (SBAC) which loaded Fe oxides) played a key role in eliminating COD and COLOR as well as in improving the biodegradability of raw wastewater. The surface reaction and hydroxyl radicals (OH) oxidation were the mechanisms for FeOx/SBAC catalytic reaction. Compared with ANMBBR-BAF process, the integrated system was more effective in abating COD, BOD5, total phenols (TPs), total nitrogen (TN) and COLOR and could shorten the retention time. Therefore, the integrated system was a promising technology for engineering applications.

  16. Albanian-NATO Relations in the Fight Against International Terrorism

    Science.gov (United States)

    2012-12-01

    Thimi Hudhra, “Beyond Strasbourgh&Kehl:Military Challenges of NATO Membership,” Revista Ushtarake, (March 2011), 36. 247 Ministry of Defense, “Speech by...and the Armed Forces,” Revista Ushtarake, (March 2011), 70. 93 Albanian-NATO relations have been eased especially because of the big public...Military Challenges of NATO Membership.” Revista Ushtarake (March 2011): 335. Institute for Democracy and Mediation Albania. Context Analysis

  17. Synthetic biology and molecular genetics in non-conventional yeasts: Current tools and future advances.

    Science.gov (United States)

    Wagner, James M; Alper, Hal S

    2016-04-01

    Coupling the tools of synthetic biology with traditional molecular genetic techniques can enable the rapid prototyping and optimization of yeast strains. While the era of yeast synthetic biology began in the well-characterized model organism Saccharomyces cerevisiae, it is swiftly expanding to include non-conventional yeast production systems such as Hansenula polymorpha, Kluyveromyces lactis, Pichia pastoris, and Yarrowia lipolytica. These yeasts already have roles in the manufacture of vaccines, therapeutic proteins, food additives, and biorenewable chemicals, but recent synthetic biology advances have the potential to greatly expand and diversify their impact on biotechnology. In this review, we summarize the development of synthetic biological tools (including promoters and terminators) and enabling molecular genetics approaches that have been applied in these four promising alternative biomanufacturing platforms. An emphasis is placed on synthetic parts and genome editing tools. Finally, we discuss examples of synthetic tools developed in other organisms that can be adapted or optimized for these hosts in the near future.

  18. International Conference on Recent Advances in Mathematical Biology, Analysis and Applications

    CERN Document Server

    Saleem, M; Srivastava, H; Khan, Mumtaz; Merajuddin, M

    2016-01-01

    The book contains recent developments and contemporary research in mathematical analysis and in its application to problems arising from the biological and physical sciences. The book is of interest to readers who wish to learn of new research in such topics as linear and nonlinear analysis, mathematical biology and ecology, dynamical systems, graph theory, variational analysis and inequalities, functional analysis, differential and difference equations, partial differential equations, approximation theory, and chaos. All papers were prepared by participants at the International Conference on Recent Advances in Mathematical Biology, Analysis and Applications (ICMBAA-2015) held during 4–6 June 2015 in Aligarh, India. A focal theme of the conference was the application of mathematics to the biological sciences and on current research in areas of theoretical mathematical analysis that can be used as sophisticated tools for the study of scientific problems. The conference provided researchers, academicians and ...

  19. Vabariigi President külastas NATO peakorterit

    Index Scriptorium Estoniae

    2008-01-01

    Ingl. k. lk. 9, pealk.: Ilves visits Brussels. President Toomas Hendrik Ilves kohtus Brüsselis NATO tippametnike ja sõjaväelastega. Eesti riigipea kohtus NATO peasekretäri Jaap de Hoop Schefferiga, esines Põhja-Atlandi Nõukogus (NAC), külastas NATO sõjalist peakorterit Euroopas (SHAPE) ja kohtus seal liitlasvägede kõrgeima sõjalise juhiga Euroopas, kindral John Craddockiga. President tegi visiidi ka Brüsseli Euroopa Kooli ning kohtus Eesti NATO-missiooni juures ja SHAPEis töötavate kaasmaalastega. Vabariigi President töövisiidil Brüsselis 3.-5.02.2008

  20. Book review: Advances in reintroduction biology of Australian and New Zealand fauna

    Science.gov (United States)

    Muths, Erin L.

    2016-01-01

    Reintroduction, and other forms of moving animals around the landscape, is an established action that has been used in the contexts of mitigation, conservation, and salvage. Advances in Reintroduction Biology of Australian and New Zealand Fauna is more than an update of its predecessor (Serena 1995). This book not only enumerates advances in reintroduction but also provides a cogent road map for understanding and applying current knowledge, and for developing future strategies.

  1. Improving AOC degradation rate by intensified biological process in advanced water treatment

    Institute of Scientific and Technical Information of China (English)

    AN Dong; LI Wei-guang; SONG Jia-xiu; CUI Fu-yi

    2007-01-01

    The object of is to evaluate assimilable organic carbon(AOC) degradation rate by intensified biological technique in advanced water treatment. By artificially acclimating and cultivating strains attached onto carbon surface, the selected strains can be intensified for their degradation to organic matters. The research indicates that ozonation process increases AOC concentration considerably, however, it is beneficial to microdegradation. Temperature and empty bed contact time ( TEBC ) are two important factors affecting microbiology. From 14 to 27 ℃, intensified biological carbon can remove AOC better compared with granular activated carbon (GAC). Under identical TEBC, intensified technique increases more than 10% AOC reduction.

  2. THE CHART ROMANIA-NATO-UE

    Directory of Open Access Journals (Sweden)

    Duduială Popescu Lorena

    2009-05-01

    Full Text Available viewed in the context of geopolitical and geostrategic current and through the elements of distinction in terms of identity and cultural institutions, chart Romania - NATO / Israel - EU stands under the sign of the common interest channel, firstly, on common values and hence the collective interests of the partners involved in the two organizational structures. Noteworthy in this context is the extent of bilateral involvement of Romania in the bodies and the politico-military, represented by NATO (the North Atlantic Treaty Organization, which is primarily military values and the construction superstate permanent expansion and development - European Union , both generating as much for our country as obligations of a politico-military security, and economic, social, institutional, cultural.

  3. Economic Benefits of Advanced Control Strategies in Biological Nutrient Removal Systems

    DEFF Research Database (Denmark)

    Carstensen, J.; Nielsen, M.K.; Harremoës, Poul

    1994-01-01

    Advances in on-line monitoring of nutrient salt concentrations and computer technology has created a large potential for the implementation of advanced and complex control strategies in biological nutrient removal systems. The majority of wastewater treatment plants today are operated with very...... strategies incorporating information from the grey box models are capable of reducing the total nitrogen discharge as well as energy costs. These results have a major impact on both existing and future plants. In fact, it is expected that future plants can be reduced with 10-20 per cent in size......, and that the complexity in reactor design of biological nutrient removal systems will be substituted by complexity in control in the future....

  4. Perceptions of NATO Burden-Sharing

    Science.gov (United States)

    1989-06-01

    the defense of NATO and Japan ... the allies (collectively) spend an average of only 3.3 percent." As noted above, the widespread use of expenditures as...those polled now believe we should be spending less than we are on the defense of Western Europe (and Japan ). Reflecting this perspective, as well as...goals of deterrence and security. 2 Despite the usefulness of expenditure data for discussion of many issues in defense policy, reliance upon spending

  5. Expanding the NATO Movement Control Network

    Science.gov (United States)

    2016-05-17

    hand, NATO movement control coun- terparts think of pallets as wooden warehouse pallets. Neither is wrong, but it can be a setback in a...of 100 vehicles, including Abrams battle tanks , to three different countries by rail and road. This was the first time that a U.S. flagged vessel...Quartermaster Basic Officer Leader Course and the Combined Logistics Captains Career Course. OPERATIONS An M1A2 Abrams tank rolls off the Liberty

  6. Biological assessment of the advanced turbine design at Wanapum Dam, 2005

    Energy Technology Data Exchange (ETDEWEB)

    Dauble, D. D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Deng, Z. D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Richmond, M. C. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Moursund, R. A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Carlson, T. J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Rakowski, C. L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Duncan, J. P. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2007-08-01

    Three studies were conducted to evaluate the biological performance of an advanced design turbine installed at Unit 8 of Wanapum Dam on the Columbia River in 2005 versus a conventional Kaplan turbine, Unit 9. The studies included an evaluation of blade-strike using deterministic and probabilistic models, integrated analysis of the response of the Sensor Fish to sever hydraulic events within the turbine system, and a novel dye technique to measure injury to juvenile salmonids in the field.

  7. Recent Advances in Biological Control of Pest Insects by Using Viruses in China

    Institute of Scientific and Technical Information of China (English)

    Xiu-lian SUN; Hui-yin PENG

    2007-01-01

    Insect viruses are attractive as biological control agents and could be a feasible alternative to chemical insecticides in the management of insect infestations. This review describes recent advances in the development of wild-type and genetically modified viruses as insecticides. A new strategy of application of insect viruses in China is reviewed. Also, the assessment of biosafety of genetically modified Helicoverpa armigera Nucleopolyhedovirus (HearNPV) is emphasized as a case-study.

  8. Instant Abdominal Wall Reconstruction with Biologic Mesh following Resection of Locally Advanced Colonic Cancer

    Directory of Open Access Journals (Sweden)

    Oskay Kaya

    2012-01-01

    Full Text Available We present a case of immediate abdominal wall reconstruction with biologic mesh following the resection of locally advanced colonic cancer. The tumor in the right colon did not respond to neoadjuvant chemotherapy. Surgical enbloc excision, including excision of the invasion in the abdominal wall, was achieved, and the defect was reconstructed with porcine dermal collagen mesh. The patient was discharged with no complication, and adaptation of the mesh was excellent at the six-month followup.

  9. NATO'S new strategic concept: a critical view

    Directory of Open Access Journals (Sweden)

    Rafael Calduch Cervera

    2011-01-01

    Full Text Available The changes that followed the adoption of the previous NATO's strategic concept in 1999 forced a review of its goals, threats and risks, as well as a new look at the capabilities of the organization at a time dominated by the economic crisis and cuts in its members’ defence budgets.On this occasion, the development of a strategic concept begun with a proposal made by a commission of experts, and a public debate which transformed the final text into a diplomatic document, not into a true useful document capable of guiding strategic planning over the next decade.These differences between the goals established by the document and the actual resources available to NATO were noted immediately with regard to the crisis management system, for which the organization does not possess the structures and civil means. It is not clear either that this limitation can be solved through cooperation with the EU. The involvement of NATO in the international mission in Libya will be the first test to ascertain the validity and effectiveness of this new strategic concept.

  10. Gruusia näitas Ukrainale NATO vajalikkust / Ihor M. Sagatsh ; interv. Evelyn Kaldoja

    Index Scriptorium Estoniae

    Sagatsh, Ihor M.

    2008-01-01

    Ukraina suursaadik NATO juures vastab küsimustele, mis puudutavad Ukraina huvi NATO-ga liitumise vastu, Gruusia sündmuste mõju, suhteid Venemaaga, EL-i, NATO ja USA abi Gruusiale, Venemaa Musta mere laevastiku viibimist Sevastoopoli sadamas. Lisa: Ihor M. Sagatsh. Vt. samas: Jushtshenko kutsus NATO jaoks pingutama

  11. 22 CFR 126.14 - Special comprehensive export authorizations for NATO, Australia, and Japan.

    Science.gov (United States)

    2010-04-01

    ... NATO, Australia, and Japan. 126.14 Section 126.14 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL... authorizations for NATO, Australia, and Japan. (a) Comprehensive authorizations. With respect to NATO members... authorization. With respect to NATO members, Australia, Japan, and Sweden, the Directorate of Defense...

  12. 75 FR 30367 - Proposed Information Collection; Comment Request; Application for NATO International Competitive...

    Science.gov (United States)

    2010-06-01

    ... Bureau of Industry and Security Proposed Information Collection; Comment Request; Application for NATO... Organization (NATO) Security Investment Program (NSIP) are only open to firms of member NATO countries. NSIP procedures for international competitive bidding (AC/4-D/2261) require that each NATO country certify...

  13. Rohkem õppusi lubav NATO harjutab Eesti kaitsmist / Evelyn Kaldoja

    Index Scriptorium Estoniae

    Kaldoja, Evelyn, 1980-

    2013-01-01

    Novembris toimuvast NATO suurõppusest "Steadfast Jazz", kus harjutatakse Eesti kaitsmist. Lätis, Leedus ja Poolas toimuval õppusel osalejate põhijõu moodustavad 2014. aastal NATO kiirreageerimisjõududesse (NRF) panustavad maad. Eesti osaleb õppusel vähemalt ühe kompaniiga

  14. NATO Operational Analysis to develop ASW Area Search Tactics

    NARCIS (Netherlands)

    Brink, M. van den; Dobson, M.; Maclachlan, A.; Vermeulen, J.F.J.

    2000-01-01

    Four years ago several NATO nations agreed to commence studies to develop tactics for ASW Area Search. The combined approach required agreement on the scope of the problem, tactical doctrine, modelling parameters and definition of terms. The NATO Area Search and Screening Working Group (AS2WG) is pr

  15. Nato odottaa Ukrainalta maan sisäisen kuohunnan rauhoittamista

    Index Scriptorium Estoniae

    2008-01-01

    Tallinnas toimunud üheksa NATO-riigi ning Ukraina kaitseministri kohtumisest. NATO peasekretär Jaap de Hoop Scheffer ja Eesti president Toomas Hendrik Ilves meenutasid, et liikmelisuse tegevuskava (Membership Action Plan, MAP) on üks vahend teiste hulgas ning see pole ainus viis, kuidas alliansi liikmeks pääseda

  16. NATO lubab Afganistanis tsiviilohvreid vähendada / Aadu Hiietamm

    Index Scriptorium Estoniae

    Hiietamm, Aadu, 1954-

    2007-01-01

    NATO peasekretäri Jaap de Hoop Schefferi ajalehele Financial Times antud usutlusest, kus ta lubab, et NATO hakkab tsiviilelanike säästmiseks Afganistani islamiliikumise Taliban vastu võitlemisel kasutama väiksemaid pomme. Pantvangide võtmisest islamistide poolt Afganistanis

  17. 22 CFR 41.25 - NATO representatives, officials, and employees.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false NATO representatives, officials, and employees... UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Foreign Government Officials § 41.25 NATO representatives, officials, and employees. (a) Classification. An alien shall be classified under the symbol...

  18. Programmed Instruction in Military Training in the NATO Nations.

    Science.gov (United States)

    Nagay, John A.

    The state of programed instruction utilization in military training within the separate North Atlantic Treaty Organization (NATO) nations is briefly assessed in this report. Only the programs of NATO countries which have not been covered in detail elsewhere are included: Netherlands, Federal Republic of Germany, Italy, Canada, France, Belgium,…

  19. Choroid plexus papillomas: advances in molecular biology and understanding of tumorigenesis.

    Science.gov (United States)

    Safaee, Michael; Oh, Michael C; Bloch, Orin; Sun, Matthew Z; Kaur, Gurvinder; Auguste, Kurtis I; Tihan, Tarik; Parsa, Andrew T

    2013-03-01

    Choroid plexus papillomas are rare, benign tumors originating from the choroid plexus. Although generally found within the ventricular system, they can arise ectopically in the brain parenchyma or disseminate throughout the neuraxis. We sought to review recent advances in our understanding of the molecular biology and oncogenic pathways associated with this disease. A comprehensive PubMed literature review was conducted to identify manuscripts discussing the clinical, molecular, and genetic features of choroid plexus papillomas. Articles concerning diagnosis, treatment, and long-term patient outcomes were also reviewed. The introduction of atypical choroid plexus papilloma as a distinct entity has increased the need for accurate histopathologic diagnosis. Advances in immunohistochemical staining have improved our ability to differentiate choroid plexus papillomas from other intracranial tumors or metastatic lesions using combinations of key markers and mitotic indices. Recent findings have implicated Notch3 signaling, the transcription factor TWIST1, platelet-derived growth factor receptor, and the tumor necrosis factor-related apoptosis-inducing ligand pathway in choroid plexus papilloma tumorigenesis. A combination of commonly occurring chromosomal duplications and deletions has also been identified. Surgical resection remains the standard of care, although chemotherapy and radiotherapy may be considered for recurrent or metastatic lesions. While generally considered benign, these tumors possess a complex biology that sheds insight into other choroid plexus tumors, particularly malignant choroid plexus carcinomas. Improving our understanding of the molecular biology, genetics, and oncogenic pathways associated with this tumor will allow for the development of targeted therapies and improved outcomes for patients with this disease.

  20. Biological processes for advancing lignocellulosic waste biorefinery by advocating circular economy.

    Science.gov (United States)

    Liguori, Rossana; Faraco, Vincenza

    2016-09-01

    The actualization of a circular economy through the use of lignocellulosic wastes as renewable resources can lead to reduce the dependence from fossil-based resources and contribute to a sustainable waste management. The integrated biorefineries, exploiting the overall lignocellulosic waste components to generate fuels, chemicals and energy, are the pillar of the circular economy. The biological treatment is receiving great attention for the biorefinery development since it is considered an eco-friendly alternative to the physico-chemical strategies to increase the biobased product recovery from wastes and improve saccharification and fermentation yields. This paper reviews the last advances in the biological treatments aimed at upgrading lignocellulosic wastes, implementing the biorefinery concept and advocating circular economy.

  1. Antibiotic abatement in different advanced oxidation processes coupled with a biological sequencing batch biofilm reactor

    Energy Technology Data Exchange (ETDEWEB)

    Esplugas, M.; Gonzalez, O.; Benito, J.; Sans, C.

    2009-07-01

    During the last decade, the lack of fresh water is becoming a major concern. Recently, the present of recalcitrant products such as pharmaceuticals has caused a special interest due to their undefined environmental impact. Among these antibiotics are one of the numerous recalcitrant pollutants present in surface waters that might not be completely removed in the biological stage of sewage treatment plants because of their antibacterial nature. Advanced Oxidation Processes (AOPs) have proved to be highly efficient for the degradation of most organic pollutants in wastewaters. (Author)

  2. Recent advances in Entamoeba biology: RNA interference, drug discovery, and gut microbiome

    Science.gov (United States)

    Singh, Upinder

    2016-01-01

    In recent years, substantial progress has been made in understanding the molecular and cell biology of the human parasite Entamoeba histolytica, an important pathogen with significant global impact. This review outlines some recent advances in the Entamoeba field in the last five years, focusing on areas that have not recently been discussed in detail: (i) molecular mechanisms regulating parasite gene expression, (ii) new efforts at drug discovery using high-throughput drug screens, and (iii) the effect of gut microbiota on amoebiasis. PMID:27853522

  3. Recent advances in computational biology, bioinformatics, medicine, and healthcare by modern OR

    OpenAIRE

    Türkay, Metin; Weber, Gerhard-Wilhelm; Blazewicz, Jacek; Rauner, Marion

    2014-01-01

    CEJOR (2014) 22:427–430 DOI 10.1007/s10100-013-0327-2 EDITORIAL Recent advances in computational biology, bioinformatics, medicine, and healthcare by modern OR Gerhard-Wilhelm Weber · Jacek Blazewicz · Marion Rauner · Metin Türkay Published online: 7 September 2013 © Springer-Verlag Berlin Heidelberg 2013 At the occasion of the 25th European Conference on Operational Research, EURO XXV 2012, July 8–11, 2012, in Vilnius, Lithuania (http://www.euro-2012.lt/), the ...

  4. Data Farming in Support of NATO

    Science.gov (United States)

    2014-03-01

    NATO context is defined as the selective and rigorous generation and application of state-of-the- art , validated knowledge for defence and security... nouveau soutien. Ce soutien est capital pour répondre à des questions inhérentes aux scénarios auxquels nous nous attendons à l’avenir, car les défis... art of modelling is to get the level of abstraction right. Too much detail in the scenario will make it nearly impossible to extract the relevant

  5. Assurance and US extended deterrence in NATO

    OpenAIRE

    Yost, David S.

    2009-01-01

    The NATO allies agreed at the Strasbourg/Kehl summit in April 2009 to prepare a new Strategic Concept for approval at their next summit. One of the issues in the Strategic Concept review will be the alliance’s nuclear deterrence posture and policy. While three members of the alliance (Britain, France and the United States) are nuclear powers, historically the greatest amount of attention has been focused on US ‘extended deterrence’—that is, the extension by Washington of an ...

  6. NATO's New Strategy in C. Asia and Its Impacts

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ Ever since the September 11 terrorist attacks, the United States and NATO have sent large troops to Afghanistan and greatly strengthened partnership for peace (PfP) with Central Asian countries. The recent dramatic political changes in some Eurasian countries have also provided U. S. and NATO favorable conditions to expand their influence and to squeeze Russia-China's strategic space.While U. S. and NATO have steadily become established in Afghanistan and some Eurasian countries, their potential threat to China's security and energy supply from Central Asia is looming large. Therefore, how to cope with the expanding U. S. -NATO's influence in Central Asia and have dialogue and cooperation with NATO have become urgent tasks for China. This article tries to explore and analyze the U. S.-NATO new strategy toward Central Asia and its potential impacts on China's security and its other interests in the region. It also makes some tentative exploration on the possibilities of China-NATO cooperation in the future.

  7. To Fly or Not to Fly: Teaching Advanced Secondary School Students about Principles of Flight in Biological Systems

    Science.gov (United States)

    Pietsch, Renée B.; Bohland, Cynthia L.; Schmale, David G., III.

    2015-01-01

    Biological flight mechanics is typically taught in graduate level college classes rather than in secondary school classes. We developed an interdisciplinary unit for advanced upper-level secondary school students (ages 15-18) to teach the principles of flight and applications to biological systems. This unit capitalised on the tremendous…

  8. The Effects of Using Concept Mapping for Improving Advanced Level Biology Students' Lower- and Higher-Order Cognitive Skills

    Science.gov (United States)

    Bramwell-Lalor, Sharon; Rainford, Marcia

    2014-01-01

    This paper reports on teachers' use of concept mapping as an alternative assessment strategy in advanced level biology classes and its effects on students' cognitive skills on selected biology concepts. Using a mixed methods approach, the study employed a pre-test/post-test quasi-experimental design involving 156 students and 8 teachers from…

  9. NATO’s Wales Summit: Expected Outcomes and Key Challenges

    Science.gov (United States)

    2014-08-26

    September 4-5, the leaders of the North Atlantic Treaty Organization’s ( NATO ) 28 member states will meet in Wales for the alliance’s 2014 summit. This...the planned completion by the end of 2014 of NATO’s mission in Afghanistan, the longest and most ambitious operation in NATO history. As such, some...analysts portray the summit as an opportunity to consider a possible strategic shift for NATO , away from the broad, “out of area” focus embodied by

  10. Recent advances in medical device triage technologies for chemical, biological, radiological, and nuclear events.

    Science.gov (United States)

    Lansdowne, Krystal; Scully, Christopher G; Galeotti, Loriano; Schwartz, Suzanne; Marcozzi, David; Strauss, David G

    2015-06-01

    In 2010, the US Food and Drug Administration (Silver Spring, Maryland USA) created the Medical Countermeasures Initiative with the mission of development and promoting medical countermeasures that would be needed to protect the nation from identified, high-priority chemical, biological, radiological, or nuclear (CBRN) threats and emerging infectious diseases. The aim of this review was to promote regulatory science research of medical devices and to analyze how the devices can be employed in different CBRN scenarios. Triage in CBRN scenarios presents unique challenges for first responders because the effects of CBRN agents and the clinical presentations of casualties at each triage stage can vary. The uniqueness of a CBRN event can render standard patient monitoring medical device and conventional triage algorithms ineffective. Despite the challenges, there have been recent advances in CBRN triage technology that include: novel technologies; mobile medical applications ("medical apps") for CBRN disasters; electronic triage tags, such as eTriage; diagnostic field devices, such as the Joint Biological Agent Identification System; and decision support systems, such as the Chemical Hazards Emergency Medical Management Intelligent Syndromes Tool (CHEMM-IST). Further research and medical device validation can help to advance prehospital triage technology for CBRN events.

  11. NATO Human View Architecture and Human Networks

    Science.gov (United States)

    Handley, Holly A. H.; Houston, Nancy P.

    2010-01-01

    The NATO Human View is a system architectural viewpoint that focuses on the human as part of a system. Its purpose is to capture the human requirements and to inform on how the human impacts the system design. The viewpoint contains seven static models that include different aspects of the human element, such as roles, tasks, constraints, training and metrics. It also includes a Human Dynamics component to perform simulations of the human system under design. One of the static models, termed Human Networks, focuses on the human-to-human communication patterns that occur as a result of ad hoc or deliberate team formation, especially teams distributed across space and time. Parameters of human teams that effect system performance can be captured in this model. Human centered aspects of networks, such as differences in operational tempo (sense of urgency), priorities (common goal), and team history (knowledge of the other team members), can be incorporated. The information captured in the Human Network static model can then be included in the Human Dynamics component so that the impact of distributed teams is represented in the simulation. As the NATO militaries transform to a more networked force, the Human View architecture is an important tool that can be used to make recommendations on the proper mix of technological innovations and human interactions.

  12. Biological Assessment of the Advanced Turbine Design at Wanapum Dam, 2005

    Energy Technology Data Exchange (ETDEWEB)

    Dauble, Dennis D.; Deng, Zhiqun; Richmond, Marshall C.; Moursund, Russell A.; Carlson, Thomas J.; Rakowski, Cynthia L.; Duncan, Joanne P.

    2007-09-12

    This report summarizes the results of studies sponsored by the U.S. Department of Energy and conducted by Pacific Northwest National Laboratory to evaluate the biological performance (likelihood of injury to fish) from an advanced design turbine installed at Unit 8 of Wanapum Dam on the Columbia River in Washington State in 2005. PNNL studies included a novel dye technique to measure injury to juvenile fish in the field, an evaluation of blade-strike using both deterministic and stochastic models, and extended analysis of the response of the Sensor Fish Device to strike, pressure, and turbulence within the turbine system. Fluorescein dye was used to evaluate injuries to live fish passed through the advanced turbine and an existing turbine at two spill discharges (15 and 17 kcfs). Under most treatments the results were not significantly different for the two turbines, however, eye injury occurred in nearly 30% of fish passing through Unit 9 but in less than 10% of those passing through Unit 8 at 15 kcfs. Both deterministic and stochastic blade-strike models were applied for the original and new AHTS turbines. The modeled probabilities were compared to the Sensor Fish results (Carlson et al. 2006) and the biological studies using juvenile fish (Normandeau et al. 2005) under the same operational parameters. The new AHTS turbine had slightly higher modeled injury rates than the original turbine, but no statistical evidence to suggest that there is significant difference in blade-strike injury probabilities between the two turbines, which is consistent with the experiment results using Sensor Fish and juvenile fish. PNNL also conducted Sensor Fish studies at Wanapum Dam in 2005 concurrent with live fish studies. The probablility of severe collision events was similar for both turbine. The advanced turbine had a slightly lower probability of severe shear events but a slightly higher probability of slight shear.

  13. USA eksperdid näevad Baltimaid NATOs / Neeme Raud

    Index Scriptorium Estoniae

    Raud, Neeme, 1969-

    2001-01-01

    USA maineka välispoliitikaga tegeleva eraorganisatsiooni Välissuhete Nõukogu (Council of Foreign Relations CFR) analüütikute seisukohad USA välispoliitikast Balti riikide NATO-ga ühinemise kohta

  14. NATO's silent side / Tomas Urbonas ; interviewed by Matthew Garrick

    Index Scriptorium Estoniae

    Urbonas, Toomas

    2011-01-01

    Afganistani provintsis Ghowr rahvusvaheliste suhete spetsialisti ja Kabulis NATO esindajana töötanud Tomas Urbonas räägib sealsest elust, kohalike elanike sõbralikkusest, oma tegevustest ja oma eluvaadetest

  15. Balts react to anti-NATO magazine article / Andris Straumanis

    Index Scriptorium Estoniae

    Straumanis, Andris

    2002-01-01

    Moskva korrespondent Jeffrey Tayler kirjutas Ameerika ajalehes The Atlantic Monthly artikli venelaste diskrimineerimisest Balti riikides ja et sellepärast ei peaks Eestit, Leedut ja Lätit NATO-sse võtma

  16. 1999 ANNUAL REPORT NATO/CCMS PILOT STUDY

    Science.gov (United States)

    This annual report present the proceedings of the second annual NATO/CCMS pilot study meeting in Belfast, UK in March 1999. Guest speakers focused on efforts in the research arena of clean products, clean processes, and pollution prevention tools.

  17. Biological efficacy and toxic effect of emergency water disinfection process based on advanced oxidation technology.

    Science.gov (United States)

    Tian, Yiping; Yuan, Xiaoli; Xu, Shujing; Li, Rihong; Zhou, Xinying; Zhang, Zhitao

    2015-12-01

    An innovative and removable water treatment system consisted of strong electric field discharge and hydrodynamic cavitation based on advanced oxidation technologies was developed for reactive free radicals producing and waterborne pathogens eliminating in the present study. The biological efficacy and toxic effects of this advanced oxidation system were evaluated during water disinfection treatments. Bench tests were carried out with synthetic microbial-contaminated water, as well as source water in rainy season from a reservoir of Dalian city (Liaoning Province, China). Results showed that high inactivation efficiency of Escherichia coli (>5 log) could be obtained for synthetic contaminated water at a low concentration (0.5-0.7 mg L(-1)) of total oxidants in 3-10 s. The numbers of wild total bacteria (108 × 10(3) CFU mL(-1)) and total coliforms (260 × 10(2) MPN 100 mL(-1)) in source water greatly reduced to 50 and 0 CFU mL(-1) respectively after treated by the advanced oxidation system, which meet the microbiological standards of drinking water, and especially that the inactivation efficiency of total coliforms could reach 100%. Meanwhile, source water qualities were greatly improved during the disinfection processes. The values of UV254 in particular were significantly reduced (60-80%) by reactive free radicals. Moreover, the concentrations of possible disinfection by-products (formaldehyde and bromide) in treated water were lower than detection limits, indicating that there was no harmful effect on water after the treatments. These investigations are helpful for the ecotoxicological studies of advanced oxidation system in the treatments of chemical polluted water or waste water. The findings of this work suggest that the developed water treatment system is ideal in the acute phases of emergencies, which also could offer additional advantages over a wide range of applications in water pollution control.

  18. The Future of NATO’s Tactical Air Doctrine

    Science.gov (United States)

    2007-11-02

    Force Attack ( FOFA ) in response to Soviet plans to move their forces forward in succeeding waves against NATO defenses.29 Although FOFA was never...movements.30 FOFA involved attacking Warsaw Pact second echelon forces before they entered the main defensive area. FOFA attacks were not necessarily...how might NATO plan to defend Baltic territory if they are asked to join the Alliance? A doctrinal analysis of possible strategies might determine that

  19. NATO’s Relevance in the Twenty-First Century

    Science.gov (United States)

    2012-03-22

    rules of engagement for force protection.19 NATO Foreign Ministers authorized the Supreme Allied Commander Europe (SACEUR) to begin the next stage of...the mission on 9 December 2004. The activation order for this next stage was given by SACEUR on 16 December 2004. It allowed the deployment of 300...Christopher Coker, Globalisation and Insecurity in the Twenty-first Century: NATO and the Management of Risk (The International Institute for Strategic

  20. NATO: Identifying New Trends within an Old Relationship

    Science.gov (United States)

    2013-05-23

    Transformation SLOC Sea Lines of Communication SNMG Standing NATO Maritime Group STROG Straits of Gibraltar UAV Unmanned Aerial Vehicles UNSCR United...considerations, population demographics changes, and unanticipated or unexpected events (for example, the rise of Hitler or the collapse of the USSR). NATO...Airborne Early Warning and Control System (AWACS) to the Straits of Gibraltar (STROG). Their mission was to protect merchant shipping and deny the

  1. Assessment of the Potential Operational Consequences of Russia Joining NATO

    Science.gov (United States)

    2011-12-01

    Rühe, Klaus Naumann, Frank Elbe and Ulrick Weisser, “It’s Time to Invite Russia to Join NATO,” Der Spiegel, 3 August, 2010, http://www.spiegel.de...Republic collapsed after it used military forces to suppress a demonstration in Prague and the popular leader Vaclav Havel rallied the opposition...and the inclusion of Slovakia would have provided Hungary with a border to other NATO countries. However, without a popular leader, such as Vaclav

  2. Architecture Considerations of Time Sensitive Targeting and NATO TST Tool

    Science.gov (United States)

    2013-06-01

    Architecture Considerations of Time Sensitive Targeting and NATO TST Tool Orhan Cetinkaya, PhD Yakup Yildirim, PhD NCI Agency, 19-21 June 2013...SAR) 18. NUMBER OF PAGES 18 19a. NAME OF RESPONSIBLE PERSON a. REPORT unclassified b . ABSTRACT unclassified c. THIS PAGE unclassified...8217’_’ _’ •_· __ ~==============================================~--0-~ __ is-ta_r_~ ~ NATO UNCLASSIFIED 18 Questions? Orhan Cetinkaya, PhD Principal Scientist

  3. Industrialization of Biology. A Roadmap to Accelerate the Advanced Manufacturing of Chemicals

    Energy Technology Data Exchange (ETDEWEB)

    Friedman, Douglas C. [National Academy of Sciences, Washington, DC (United States)

    2015-09-01

    The report stresses the need for efforts to inform the public of the nature of industrial biotechnology and of its societal benefits, and to make sure that concerns are communicated effectively between the public and other stakeholders. In addition to scientific advances, a number of governance and societal factors will influence the industrialization of biology. Industry norms and standards need to be established in areas such as read/write accuracy for DNA, data and machine technology specifications, and organism performance in terms of production rates and yields. An updated regulatory regime is also needed to accelerate the safe commercialization of new host organisms, metabolic pathways, and chemical products, and regulations should be coordinated across nations to enable rapid, safe, and global access to new technologies and products.

  4. Recent advances in the structural molecular biology of Ets transcription factors: interactions, interfaces and inhibition.

    Science.gov (United States)

    Cooper, Christopher D O; Newman, Joseph A; Gileadi, Opher

    2014-02-01

    The Ets family of eukaryotic transcription factors is based around the conserved Ets DNA-binding domain. Although their DNA-binding selectivity is biochemically and structurally well characterized, structures of homodimeric and ternary complexes point to Ets domains functioning as versatile protein-interaction modules. In the present paper, we review the progress made over the last decade to elucidate the structural mechanisms involved in modulation of DNA binding and protein partner selection during dimerization. We see that Ets domains, although conserved around a core architecture, have evolved to utilize a variety of interaction surfaces and binding mechanisms, reflecting Ets domains as dynamic interfaces for both DNA and protein interaction. Furthermore, we discuss recent advances in drug development for inhibition of Ets factors, and the roles structural biology can play in their future.

  5. Recent Advancements and Biological Activities of Aryl Propionic Acid Derivatives: (A Review

    Directory of Open Access Journals (Sweden)

    Harshita Dhall

    2016-08-01

    Full Text Available The aryl propionic acid derivatives belong to an important class of NSAIDs (Non Steroidal Anti-inflammatory Drugs. Ibuprofen, chemically called 2-(4-isobutyl phenyl propionic acid, is a well known NSAID. Aryl propionic acid derivatives possesses a wide range of biological activities including anti-bacterial, anti-convulsant, anti-cancer, analgesic and anti-inflammatory activities. Apart from very potent compounds in the field of analgesics and antipyrectics as Ibuprofen, Oxaprozin, Ketoprofen, Fenoprofen; aryl propionic acid derivatives plays important role to treat other ailments also. Through this review, an attempt has been made to emphasize on recent work done and recent advancements in arena of aryl propionic acid derivatives in view of medicinal chemistry.

  6. AICD -- Advanced Industrial Concepts Division Biological and Chemical Technologies Research Program. 1993 Annual summary report

    Energy Technology Data Exchange (ETDEWEB)

    Petersen, G.; Bair, K.; Ross, J. [eds.

    1994-03-01

    The annual summary report presents the fiscal year (FY) 1993 research activities and accomplishments for the United States Department of Energy (DOE) Biological and Chemical Technologies Research (BCTR) Program of the Advanced Industrial Concepts Division (AICD). This AICD program resides within the Office of Industrial Technologies (OIT) of the Office of Energy Efficiency and Renewable Energy (EE). The annual summary report for 1993 (ASR 93) contains the following: A program description (including BCTR program mission statement, historical background, relevance, goals and objectives), program structure and organization, selected technical and programmatic highlights for 1993, detailed descriptions of individual projects, a listing of program output, including a bibliography of published work, patents, and awards arising from work supported by BCTR.

  7. SysBioMed report: advancing systems biology for medical applications.

    Science.gov (United States)

    Wolkenhauer, O; Fell, D; De Meyts, P; Blüthgen, N; Herzel, H; Le Novère, N; Höfer, T; Schürrle, K; van Leeuwen, I

    2009-05-01

    The following report selects and summarises some of the conclusions and recommendations generated throughout a series of workshops and discussions that have lead to the publication of the Science Policy Briefing (SPB) Nr. 35, published by the European Science Foundation. (Large parts of the present text are directly based on the ESF SPB. Detailed recommendations with regard to specific application areas are not given here but can be found in the SPB. Issues related to mathematical modelling, including training and the need for an infrastructure supporting modelling are discussed in greater detail in the present text.)The numerous reports and publications about the advances within the rapidly growing field of systems biology have led to a plethora of alternative definitions for key concepts. Here, with 'mathematical modelling' the authors refer to the modelling and simulation of subcellular, cellular and macro-scale phenomena, using primarily methods from dynamical systems theory. The aim of such models is encoding and testing hypotheses about mechanisms underlying the functioning of cells. Typical examples are models for molecular networks, where the behaviour of cells is expressed in terms of quantitative changes in the levels of transcripts and gene products. Bioinformatics provides essential complementary tools, including procedures for pattern recognition, machine learning, statistical modelling (testing for differences, searching for associations and correlations) and secondary data extracted from databases.Dynamical systems theory is the natural language to investigate complex biological systems demonstrating nonlinear spatio-temporal behaviour. However, the generation of experimental data suitable to parameterise, calibrate and validate such models is often time consuming and expensive or not even possible with the technology available today. In our report, we use the term 'computational model' when mathematical models are complemented with information

  8. Advanced high school biology in an era of rapid change: a summary of the biology panel report from the NRC Committee on Programs for Advanced Study of Mathematics and Science in American High Schools.

    Science.gov (United States)

    Wood, William B

    2002-01-01

    A recently released National Research Council (NRC) report, Learning and Understanding: Improving Advanced Study of Mathematics and Science in U.S. High Schools, evaluated and recommended changes in the Advanced Placement (AP), International Baccalaureate (IB), and other advanced secondary school science programs. As part of this study, discipline-specific panels were formed to evaluate advanced programs in biology, chemistry, physics, and mathematics. Among the conclusions of the Content Panel for Biology were that AP courses in particular suffer from inadequate quality control as well as excessive pressure to fulfill their advanced placement function, which encourages teachers to attempt coverage of all areas of biology and emphasize memorization of facts rather than in-depth understanding. In this essay, the Panel's principal findings are discussed, with an emphasis on its recommendation that colleges and universities should be strongly discouraged from using performance on either the AP examination or the IB examination as the sole basis for automatic placement out of required introductory courses for biology majors and distribution requirements for nonmajors.

  9. NATO Network Enabled Capability (NNEC) challenges: Why NATO Air Command and Control System (ACCS) might be a good case?

    Science.gov (United States)

    2011-06-01

    Picture ( RAP ), Air Tasking Order (ATO), Air Coordination order (ACO), etc. 2. Non Functional: providing all other functionalities, e.g. IA/security...IBM, BEA, Raytheon, etc.), fielded national systems, NATO systems and prototypes (Euro Fighter, ICC, JADOCS, JCOP, JTS, MUSIC , NE-3A, Nor BFTS...instance, the RAP and FFT dissemination to internal as well as to external entities. The approach will be of benefit to ACCS and NATO C3 in the future

  10. The NATO III 5 MHz Distribution System

    Science.gov (United States)

    Vulcan, A.; Bloch, M.

    1981-01-01

    A high performance 5 MHz distribution system is described which has extremely low phase noise and jitter characteristics and provides multiple buffered outputs. The system is completely redundant with automatic switchover and is self-testing. Since the 5 MHz reference signals distributed by the NATO III distribution system are used for up-conversion and multiplicative functions, a high degree of phase stability and isolation between outputs is necessary. Unique circuit design and packaging concepts insure that the isolation between outputs is sufficient to quarantee a phase perturbation of less than 0.0016 deg when other outputs are open circuited, short circuited or terminated in 50 ohms. Circuit design techniques include high isolation cascode amplifiers. Negative feedback stabilizes system gain and minimizes circuit phase noise contributions. Balanced lines, in lieu of single ended coaxial transmission media, minimize pickup.

  11. Advances in wastewater nitrogen removal by biological processes: state of the art review

    Directory of Open Access Journals (Sweden)

    Andrea G. Capodaglio

    2016-04-01

    Full Text Available The paper summarizes the state-of-the-art of the most recent advances in biological nitrogen removal, including process design criteria and technological innovations. With reference to the Modified Ludzck Ettinger (MLE process (pre-denitrification and nitrification in the activated sludge process, the most common nitrogen removal process used nowadays, a new design equation for the denitrification reactor based on specific denitrification rate (SDNR has been proposed. In addition, factors influencing SDNR (DO in the anoxic reactor; hydrodynamic behavior are analyzed, and technological solutions are proposed. Concerning technological advances, the paper presents a summary of various “deammonification” processes, better known by their patent names like ANAMMOX®, DEMON®, CANON®, ANITA® and others. These processes have already found applications in the treatment of high-strength wastewater such as digested sludge liquor and landfill leachate. Among other emerging denitrification technologies, consideration is given to the Membrane Biofilm Reactors (MBfRs that can be operated both in oxidation and reduction mode.

  12. Trends and Advances in Separation and Detection of SSRIs and SNRIs in Biological Matrices

    Directory of Open Access Journals (Sweden)

    Ruchita Das

    2013-01-01

    Full Text Available Nowadays antidepressant drugs like selective serotonin reuptake inhibitors (SSRIs and selective norepinephrine reuptake inhibitors (SNRIs represent the first choice in the treatment of moderate to severe depressive illness, various phobias, and personality disorders. In spite of the therapeutic aspects, they often produce very severe and toxic effects in deliberate and accidental cases of poisoning. These are also considered as date-rape drugs used for drugged victims for raping or robbing. Therefore, in recent years, their analyses in different biological matrices for clinical and toxicological analysis purposes has been a target worthy of interest. Thus, the review focuses on recent advancements of various separation techniques like chromatography and electrophoresis that are concernd with the determination of selective serotonin reuptake inhibitor and selective norepinephrine reuptake inhibitor drugs and their metabolites in various biological matrices. In addition to this, a critical discussion on analytical approaches has also been incorporated, suggesting their applicability and limitations for further implementations. Thus, this paper will definitely help in the selection and development of proper analytical methodologies to achieve satisfactory results, better scientific understanding, and test interpretation.

  13. Vermicomposting as an advanced biological treatment for industrial waste from the leather industry.

    Science.gov (United States)

    Nunes, Ramom R; Bontempi, Rhaissa M; Mendonça, Giovane; Galetti, Gustavo; Rezende, Maria Olímpia O

    2016-01-01

    The leather industry (tanneries) generates high amounts of toxic wastes, including solid and liquid effluents that are rich in organic matter and mineral content. Vermicomposting was studied as an alternative method of treating the wastes from tanneries. Vermicompost was produced from the following tannery residues: tanned chips of wet-blue leather, sludge from a liquid residue treatment station, and a mixture of both. Five hundred earthworms (Eisenia fetida) were added to each barrel. During the following 135 days the following parameters were evaluated: pH, total organic carbon (TOC), organic matter (OM), cation exchange capacity (CEC), C:N ratio, and chromium content as Cr (III) and Cr (VI). The results for pH, TOC and OM contents showed decreases in their values during the composting process, whereas values for CEC and total nitrogen rose, indicating that the vermicompost reached maturity. For chromium, at 135 days, all values of Cr (VI) were below the detectable level. Therefore, the Cr (VI) content had probably been biologically transformed into Cr (III), confirming the use of this technique as an advanced biological treatment. The study reinforces the idea that vermicomposting could be introduced as an effective technology for the treatment of industrial tannery waste and the production of agricultural inputs.

  14. Combination of Advanced Oxidation Processes and biological treatments for wastewater decontamination-A review

    Energy Technology Data Exchange (ETDEWEB)

    Oller, I., E-mail: isabel.oller@psa.es [Plataforma Solar de Almeria (CIEMAT), Carretera Senes, Km 4. 04200 Tabernas (Almeria) (Spain); Malato, S. [Plataforma Solar de Almeria (CIEMAT), Carretera Senes, Km 4. 04200 Tabernas (Almeria) (Spain); Sanchez-Perez, J.A. [Department of Chemical Engineering, University of Almeria, Crta de Sacramento s/n, 04120 Almeria (Spain)

    2011-09-15

    Nowadays there is a continuously increasing worldwide concern for development of alternative water reuse technologies, mainly focused on agriculture and industry. In this context, Advanced Oxidation Processes (AOPs) are considered a highly competitive water treatment technology for the removal of those organic pollutants not treatable by conventional techniques due to their high chemical stability and/or low biodegradability. Although chemical oxidation for complete mineralization is usually expensive, its combination with a biological treatment is widely reported to reduce operating costs. This paper reviews recent research combining AOPs (as a pre-treatment or post-treatment stage) and bioremediation technologies for the decontamination of a wide range of synthetic and real industrial wastewater. Special emphasis is also placed on recent studies and large-scale combination schemes developed in Mediterranean countries for non-biodegradable wastewater treatment and reuse. The main conclusions arrived at from the overall assessment of the literature are that more work needs to be done on degradation kinetics and reactor modeling of the combined process, and also dynamics of the initial attack on primary contaminants and intermediate species generation. Furthermore, better economic models must be developed to estimate how the cost of this combined process varies with specific industrial wastewater characteristics, the overall decontamination efficiency and the relative cost of the AOP versus biological treatment.

  15. IBPRO - A Novel Short-Duration Teaching Course in Advanced Physics and Biology Underlying Cancer Radiotherapy.

    Science.gov (United States)

    Joiner, Michael C; Tracey, Monica W; Kacin, Sara E; Burmeister, Jay W

    2017-03-22

    This article provides a summary and status report of the ongoing advanced education program IBPRO - Integrated course in Biology and Physics of Radiation Oncology. IBPRO is a five-year program funded by NCI. It addresses the recognized deficiency in the number of mentors available who have the required knowledge and skill to provide the teaching and training that is required for future radiation oncologists and researchers in radiation sciences. Each year, IBPRO brings together 50 attendees typically at assistant professor level and upwards, who are already qualified/certified radiation oncologists, medical physicists or biologists. These attendees receive keynote lectures and activities based on active learning strategies, merging together the clinical, biological and physics underpinnings of radiation oncology, at the forefront of the field. This experience is aimed at increasing collaborations, raising the level and amount of basic and applied research undertaken in radiation oncology, and enabling attendees to confidently become involved in the future teaching and training of researchers and radiation oncologists.

  16. NATO komandörid käisid allveelaevahirmu ohjamas / Virkko Lepassalu

    Index Scriptorium Estoniae

    Lepassalu, Virkko, 1971-

    2016-01-01

    Juunis saabub Tallinna NATO õppusele BALTOPS 2016 mitu tuhat sõjalaevastiklast. Tallinna abilinnapea Kalle Klandorfi kohtumisest NATO 1. alalise mereväegrupi ülemakohusetäitja Jose Enricue Delgadoga

  17. Development and implementation of a NATO-wide state-of-the-art interim geospatial intelligence support tool

    Science.gov (United States)

    Teufert, John F.

    2004-09-01

    In order to enhance operational planning capabilities of the NATO Force Headquarters (KFOR, SFOR, ISAF), the NC3A Geo Team has developed a web-based interim geospatial intelligence support tool (IGEOSIT). The NC3A IGEOSIT displays geospatial data, such as digital topographic maps and satellite/air photo imagery, together with selectable overlay objects retrieved from distributed operational databases (DBs), for example minefields, bridges, culverts and military units. The NC3A IGEOSIT is a state-of-the-art web-based and Java-based multi-tier solution consisting of applications distributed over multiple servers within each Force HQ. The IGEOSIT provides advanced GIS terrain analysis capabilities based on the available Geo-data, including line-of-sight, 3-D perspective views, terrain profiles, and the definition of go/no-go areas. The system also performs vector-based route analysis and enhances the real-time tracking capabilities of mobile vehicles and troops. The IGEOSIT analyzes overlay data sets according to their attributes and dependencies in order to highlight otherwise hidden spatial relations that may be critical for mission planning. After performing geospatial analysis, the system compiles maps automatically to provide the user with immediate hard copy results, according to NATO standards, if necessary. The successful implementation of the IGEOSIT currently provides all NATO FORCE HQ staff members with a common operational picture of the theatre. This ensures that a common set of recently-updated information overlays forms the basis for all operational decisions. This paper describes the architecture, technology, performance tests (including test environment, analysis and measurement tools, hardware, selected test scenarios and results) and the lessons learned implementing advanced network and Java-based multi-tier solutions within the NATO Force Headquarters.

  18. Arab Public Opinion and NATO after the International Military Operations in Libya

    OpenAIRE

    Saddiki, Said

    2012-01-01

    Although, NATO has always taken into account public opinion in its member states, the emergence of new Information and Communication Technologies and the extension of its out-of- area operations have given NATO a new impetus to extend the space of communication beyond the Alliance countries.With regard to the NATO's partnership with Arab countries, the Arab spring uprisings have created a new political atmosphere in which many signs of a positive perception of NATO and its members states...

  19. Sword or Ploughshare? New Roles for NATO and the Changing Nature of Transatlantic Relations

    Science.gov (United States)

    2008-02-01

    very personal description of the events in NATO that led to the invocation of Article 5 by Edgar Buckley, “Invoking Article 5,” NATO Review, Summer...Afghanistan. In the summer of 2007, more than 37 nations had stationed approximately 40,000 113 Edgar Buckley...160. 187 “Kehrt Frankreich in die NATO zurück? Bilderstürmerische Überlegungen von Verteidigungsminister Morin ” [Will France Rejoin NATO

  20. Jack Deverell : NATO ei kao kuhugi / Jack Deverell ; interv. Margus Kolga

    Index Scriptorium Estoniae

    Deverell, Jack

    2005-01-01

    NATO põhjapiirkonna vägede endise juhi arvates võiks NATO olla endiselt peamine sõjalise jõu instrument, olgu tegemis siis NATO või EL-i juhitud sõjalise operatsiooniga, ta ei usu, et NATO ja EL muutuvad sõjaliselt ning poliitiliselt omavahel võistlevateks organisatsioonideks. Riigid peaksid tegutsema koos selliste sõjaliste võimete loomisel, milleks nad üksi suutelised ei ole

  1. Moskva hoiatas Ukrainat NATO püüdluste eest / Krister Paris

    Index Scriptorium Estoniae

    Paris, Krister

    2006-01-01

    Krimmis protestiti plaanitavate NATO ühisõppuste vastu, Vene riigiduuma väljendas muret Ukraina plaani pärast ühineda NATO-ga. Samas toetab NATO-ga ühinemist vaid 20% küsitletud Ukraina elanikest

  2. NATO, the Baltic states and Russia : a framework for sustainable enlargement / Mark Kramer

    Index Scriptorium Estoniae

    Kramer, Mark

    2002-01-01

    Baltimaad said 2002. aasta novembris toimunud Praha tippkohtumisel kutse NATO-ga liitumiseks. Autor analüüsib selle kutse tagamaid, võimalikku mõju NATO ja Venemaa suhetele ning leiab, et viimasega suhete parandamiseks peaks julgustama Venemaad samuti NATO-ga liituma

  3. Kosovo Armed Forces Development; Achieving NATO Non-Article 5 Crisis Response Operations Interoperability

    Science.gov (United States)

    2014-12-12

    KOSOVO ARMED FORCES DEVELOPMENT; ACHIEVING NATO NON-ARTICLE 5 CRISIS RESPONSE OPERATIONS INTEROPERABILITY A thesis presented...Achieving NATO Non- Article 5 Crisis Response Operations Interoperability 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6...authorities, and participation in international operations. One of objective of Kosovo Armed Forces is to be fully interoperable with NATO members, in

  4. 77 FR 25892 - Security Zones; North Atlantic Treaty Organization (NATO) Summit, Chicago, IL

    Science.gov (United States)

    2012-05-02

    ... No. USCG-2012-0052] RIN 1625-AA87 Security Zones; North Atlantic Treaty Organization (NATO) Summit... River during the NATO Summit. This statement is incorrect. The Coast Guard received one comment. DATES... explained that it expects the NATO conference to have [[Page 25893

  5. 48 CFR 245.603-71 - Disposal of contractor inventory for NATO cooperative projects.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Disposal of contractor inventory for NATO cooperative projects. 245.603-71 Section 245.603-71 Federal Acquisition Regulations... inventory for NATO cooperative projects. (a) North Atlantic Treaty Organization (NATO) cooperative...

  6. 78 FR 17221 - Agency Information Collection Activities: Interagency Record of Request A, G, or NATO Dependent...

    Science.gov (United States)

    2013-03-20

    ... Record of Request A, G, or NATO Dependent Employment Authorization or Change/ Adjustment To/From A, G, or NATO Status, Form I-566; Revision of a Currently Approved Collection; Extension ACTION: 30-day notice.../Collection: Interagency Record of Request A, G, or NATO Dependent Employment Authorization or...

  7. 78 FR 24158 - Proposed Information Collection; Comment Request; Application for NATO International Competitive...

    Science.gov (United States)

    2013-04-24

    ... Bureau of Industry and Security Proposed Information Collection; Comment Request; Application for NATO... Atlantic Treaty Organization (NATO) Security Investment Program (NSIP) are only open to firms of member NATO countries. NSIP procedures for international competitive bidding (AC/4-D/2261) require that...

  8. Endise NATO kõrge juhi sõnul on Afganistan alliansi proovikivi / Harald Kujat ; interv. Erkki Bahovski

    Index Scriptorium Estoniae

    Kujat, Harald

    2006-01-01

    Kindral, endine NATO sõjalise komitee esimees räägib alliansi tegevusest turvalisuse tagamisel Afganistanis, Eesti osalemisest NATO missioonil, NATO õhupatrullidest Baltimaades. Harald Kujati CV. Vt. samas: NATO võttis mässu summutamise oma õlule

  9. 78 FR 51801 - 30-Day Notice of Proposed Information Collection: Application for A, G, or NATO Visa

    Science.gov (United States)

    2013-08-21

    ... Notice of Proposed Information Collection: Application for A, G, or NATO Visa ACTION: Notice of request... Collection: Application for A, G, or NATO Visas OMB Control Number: 1405-0100 Type of Request: Extension of a... for A, G or NATO visa reauthorizations, excluding A-3, G-5 or NATO applicants Estimated Number...

  10. 78 FR 32696 - 60-Day Notice of Proposed Information Collection: Application for A, G, or NATO Visa

    Science.gov (United States)

    2013-05-31

    ... Notice of Proposed Information Collection: Application for A, G, or NATO Visa ACTION: Notice of request..., G, or NATO Visas. OMB Control Number: OMB No. 1405-0100. Type of Request: Extension of a Currently..., G, or NATO visa reauthorizations, excluding A-3, G-5 and NATO-7 applicants. Estimated Number...

  11. The oral histories of six African American males in their ecology of Advanced Placement Biology

    Science.gov (United States)

    Halasa, Katrina Bassam

    The major purpose of this qualitative study was to examine the past in order to understand the complex phenomenon of students engaging in science (Newman, Ridenour, Newman, & DeMarco, 2003) specifically through the oral histories of six self-identified African American males enrolled in a high school Advanced Placement Biology class and the oral histories about events that followed during their post high school experiences. To elucidate an understanding of this phenomenon, this research explored the ecology of African American males' descriptions of their school science, their peer school science community, their lived experiences during and after graduation, and their meso-community (Bronfenbrenner, 1979). Many minority and low-income students are less likely to enroll in rigorous courses during high school (Education Trust, 2006). This study is of utmost importance because capturing the informants' oral histories may improve rigorous science education. Many African American male students are attending urban schools with an ever growing achievement gap among their White counterparts (Norman, Ault, Bentz, & Meskimen, 2001); therefore, they are disengaging in science. As a result, African American males are underrepresented in both science careers and achievements in science (Atwater, 2000; National Science Foundation, 1994). The six oral histories highlighted the ecological factors that affected African American males regarding (1) the impact of their relationship with their mothers, (2) the understanding of personal responsibility, (3) the notion of a scientist, (4) the issue of gender being more of an obstacle than race, (5) the understanding that education is valuable, (6) the interactions and influence of relationships with others on their decisions, (7) the development of integrity through the participation in sports, (8) the ecological neighborhood environment influences an image, (9) the enrollment of Advanced Placement Biology course helped the transition

  12. Remediation of a winery wastewater combining aerobic biological oxidation and electrochemical advanced oxidation processes.

    Science.gov (United States)

    Moreira, Francisca C; Boaventura, Rui A R; Brillas, Enric; Vilar, Vítor J P

    2015-05-15

    Apart from a high biodegradable fraction consisting of organic acids, sugars and alcohols, winery wastewaters exhibit a recalcitrant fraction containing high-molecular-weight compounds as polyphenols, tannins and lignins. In this context, a winery wastewater was firstly subjected to a biological oxidation to mineralize the biodegradable fraction and afterwards an electrochemical advanced oxidation process (EAOP) was applied in order to mineralize the refractory molecules or transform them into simpler ones that can be further biodegraded. The biological oxidation led to above 97% removals of dissolved organic carbon (DOC), chemical oxygen demand (COD) and 5-day biochemical oxygen demand (BOD5), but was inefficient on the degradation of a bioresistant fraction corresponding to 130 mg L(-1) of DOC, 380 mg O2 L(-1) of COD and 8.2 mg caffeic acid equivalent L(-1) of total dissolved polyphenols. Various EAOPs such as anodic oxidation with electrogenerated H2O2 (AO-H2O2), electro-Fenton (EF), UVA photoelectro-Fenton (PEF) and solar PEF (SPEF) were then applied to the recalcitrant effluent fraction using a 2.2 L lab-scale flow plant containing an electrochemical cell equipped with a boron-doped diamond (BDD) anode and a carbon-PTFE air-diffusion cathode and coupled to a photoreactor with compound parabolic collectors (CPCs). The influence of initial Fe(2+) concentration and current density on the PEF process was evaluated. The relative oxidative ability of EAOPs increased in the order AO-H2O2 process using an initial Fe(2+) concentration of 35 mg L(-1), current density of 25 mA cm(-2), pH of 2.8 and 25 °C reached removals of 86% on DOC and 68% on COD after 240 min, regarding the biologically treated effluent, along with energy consumptions of 45 kWh (kg DOC)(-1) and 5.1 kWh m(-3). After this coupled treatment, color, odor, COD, BOD5, NH4(+), NO3(-) and SO4(2-) parameters complied with the legislation targets and, in addition, a total dissolved polyphenols content of 0

  13. Final Technical Report - Use of Systems Biology Approaches to Develop Advanced Biofuel-Synthesizing Cyanobacterial Strains

    Energy Technology Data Exchange (ETDEWEB)

    Pakrasi, Himadri [Washington Univ., St. Louis, MO (United States)

    2016-09-01

    The overall objective of this project was to use a systems biology approach to evaluate the potentials of a number of cyanobacterial strains for photobiological production of advanced biofuels and/or their chemical precursors. Cyanobacteria are oxygen evolving photosynthetic prokaryotes. Among them, certain unicellular species such as Cyanothece can also fix N2, a process that is exquisitely sensitive to oxygen. To accommodate such incompatible processes in a single cell, Cyanothece produces oxygen during the day, and creates an O2-limited intracellular environment during the night to perform O2-sensitive processes such as N2-fixation. Thus, Cyanothece cells are natural bioreactors for the storage of captured solar energy with subsequent utilization at a different time during a diurnal cycle. Our studies include the identification of a novel, fast-growing, mixotrophic, transformable cyanobacterium. This strain has been sequenced and will be made available to the community. In addition, we have developed genome-scale models for a family of cyanobacteria to assess their metabolic repertoire. Furthermore, we developed a method for rapid construction of metabolic models using multiple annotation sources and a metabolic model of a related organism. This method will allow rapid annotation and screening of potential phenotypes based on the newly available genome sequences of many organisms.

  14. Technological advances for deciphering the complexity of psychiatric disorders: merging proteomics with cell biology.

    Science.gov (United States)

    Wesseling, Hendrik; Guest, Paul C; Lago, Santiago G; Bahn, Sabine

    2014-08-01

    Proteomic studies have increased our understanding of the molecular pathways affected in psychiatric disorders. Mass spectrometry and two-dimensional gel electrophoresis analyses of post-mortem brain samples from psychiatric patients have revealed effects on synaptic, cytoskeletal, antioxidant and mitochondrial protein networks. Multiplex immunoassay profiling studies have found alterations in hormones, growth factors, transport and inflammation-related proteins in serum and plasma from living first-onset patients. Despite these advances, there are still difficulties in translating these findings into platforms for improved treatment of patients and for discovery of new drugs with better efficacy and side effect profiles. This review describes how the next phase of proteomic investigations in psychiatry should include stringent replication studies for validation of biomarker candidates and functional follow-up studies which can be used to test the impact on physiological function. All biomarker candidates should now be tested in series with traditional and emerging cell biological approaches. This should include investigations of the effects of post-translational modifications, protein dynamics and network analyses using targeted proteomic approaches. Most importantly, there is still an urgent need for development of disease-relevant cellular models for improved translation of proteomic findings into a means of developing novel drug treatments for patients with these life-altering disorders.

  15. The Research & Technology Organisation (RTO) and The NATO Modelling & Simulation Group (NMSG)

    Science.gov (United States)

    2010-02-01

    The Research & Technology Organisation (RTO) The NATO Modelling & Simulation Group (NMSG) NATO - OTAN Briefing to the MSG-079 Workshop...Participating to M&S related events – ITEC, I/ITSEC – SISO International Workshops – National M&S Conferences (IberSIM 09, USMOS 09) … NATO - OTAN NMSG...Deadline for abstracts 30 May 2010 C-BML presence in the NMSG Events NMSG: MS3 M&S Standardisation in NATO OTAN - NATO NMSG M&S Standards Activity

  16. NATO Advanced Research Workshop on Inverse Methods in Electromagnetic Imaging

    CERN Document Server

    Brand, Hans; Cram, Leonard; Gjessing, Dag; Jordan, Arthur; Keydel, Wolfgang; Schwierz, Günther; Vogel, Martin

    1985-01-01

    In recent years, there has been an increased interest in the use of polarization effects for radar and electromagnetic imaging problems (References 1, 2, and 3). The problem of electro­ magnetic imaging can be divided into the following areas: (1) Propagation of the Stokes' vector from the transmitter to the target region through various atmospheric conditions (rain, dust, fog, clouds, turbulence, etc.). (2) Scattering of the Stokes' vector from the object. (3) Scattering of the Stokes' vector from the rough surface, terrain, and the volume scattering. (4) Propagation of the Stokes' vector from the target region to the receiver. (5) The characteristics of the receiver relating the Stokes' vector to the output. The propagation characteristics of the Stokes' vector through various media can be described by the equation of transfer. Even though the scalar equation of transfer has been studied extensively in the past, the vector equation of transfer has not received as much attention. In recent years, however, a...

  17. NATO Advanced Research Workshop on Fundamental and Applied Electromagnetics

    CERN Document Server

    Maksimenko, Sergey

    2016-01-01

    This book presents the most relevant and recent results in the study of “Nanoelectromagnetics”, a recently born fascinating research discipline, whose popularity is fast arising with the intensive penetration of nanotechnology in the world of electronics applications. Studying nanoelectromagnetics means describing the interaction between electromagnetic radiation and quantum mechanical low-dimensional systems: this requires a full interdisciplinary approach, the reason why this book hosts contributions from the fields of fundamental and applied electromagnetics, of chemistry and technology of nanostructures and nanocomposites, of physics of nano-structures systems, etc. The book is aimed at providing the reader with the state of the art in Nanoelectromagnetics, from theoretical modelling to experimental characterization, from design to synthesis, from DC to microwave and terahertz applications, from the study of fundamental material properties to the analysis of complex systems and devices, from commercia...

  18. NATO Advanced Study Institute on Atoms in Unusual Situations

    CERN Document Server

    1986-01-01

    Atomic Physics is certainly the oldest field in which Quantum Mechanics has been used and has provided the most significant proofs of this new theory. Most of the basic concepts, except those more recently developed in field quantization, have been understood for quite a time. Atomic Physics began to serve as a basis for other fields such as molecu­ lar, solid state or nuclear physics. A renewal of interest in Atomic Physics began in the sixties, after the discovery of Quantum Electro­ dynamics, and later when it provided some basic tests of fundamental questions like parity violation, time reversal or Dirac theory. More recently the development of new technologies led to the ex­ ploration of very extreme cases in which the most secrete aspects of atoms have been observed. - Rydberg states where the atoms are so big that they can be described by classical theories; - Heavy or super-heavy ions or exotic atoms where unknown QED or relativistic effects can be observed (very heavy hydrogenlike or heliu...

  19. NATO Advanced Study Institute on Insurance and Risk Theory

    CERN Document Server

    Vylder, F; Haezendonck, J

    1986-01-01

    Canadian financial institutions have been in rapid change in the past five years. In response to these changes, the Department of Finance issued a discussion paper: The Regulation of Canadian Financial Institutions, in April 1985, and the government intends to introduce legislation in the fall. This paper studi.es the combinantion of financial institutions from the viewpoint of ruin probability. In risk theory developed to describe insurance companies [1,2,3,4,5J, the ruin probability of a company with initial reserve (capital) u is 6 1 -:;-7;;f3 u 1jJ(u) = H6 e H6 (1) Here,we assume that claims arrive as a Poisson process, and the claim amount is distributed as exponential distribution with expectation liS. 6 is the loading, i.e., premium charged is (1+6) times expected claims. Financial institutions are treated as "insurance companies": the difference between interest charged and interest paid is regarded as premiums, loan defaults are treated as claims.

  20. NATO Advanced Study Institute on Molecular Physics and Hypersonic Flows

    CERN Document Server

    1996-01-01

    Molecular Physics and Hypersonic Flows bridges the gap between the fluid dynamics and molecular physics communities, emphasizing the role played by elementary processes in hypersonic flows. In particular, the work is primarily dedicated to filling the gap between microscopic and macroscopic treatments of the source terms to be inserted in the fluid dynamics codes. The first part of the book describes the molecular dynamics of elementary processes both in the gas phase and in the interaction with surfaces by using quantum mechanical and phenomenological approaches. A second group of contributions describes thermodynamics and transport properties of air components, with special attention to the transport of internal energy. A series of papers is devoted to the experimental and theoretical study of the flow of partially ionized gases. Subsequent contributions treat modern computational techniques for 3-D hypersonic flow. Non-equilibrium vibrational kinetics are then described, together with the coupling of vibra...

  1. Advancing Simulation Reusability - Report on NATO MSG-042 Findings

    NARCIS (Netherlands)

    Reif, B.M.; Wharton, W.D.; Gonzalez-Godoy, S.; McGlynn, L.; San Jose, A.; Elliot, R.; Franzen, S.; Lecenq, X.; Huiskamp, W.; Edmondson, D.

    2007-01-01

    In many cases, the training and decision support needs of military users are urgent; operations cannot wait and missions have to be accomplished. Simulators, wargames scenarios and experiments should be ready 'yesterday'. New kinds of operations, environments, tactics, equipment and force configurat

  2. Advancing Simulation Reusability - Report on NATO MSG-042 Findings

    NARCIS (Netherlands)

    Reif, B.M.; Wharton, W.D.; Gonzalez-Godoy, S.; McGlynn, L.; San Jose, A.; Elliot, R.; Franzen, S.; Lecinq, X.; Huiskamp, W.; Edmondson, D.

    2006-01-01

    In many cases, the training and decision support needs of military users are urgent; operations can not wait and missions have to be accomplished. Simulators, wargames scenarios and experiments should be ready 'yesterday'. New kinds of operations, environments, tactics, equipment and force configura

  3. NATO Advanced Study Institute on New Aspects of Nuclear Dynamics

    CERN Document Server

    Huberts, P

    1989-01-01

    The 1988 Summer School on New Aspects of Nuclear Dynamics took place in the style that by now has become a tradition: a series of lectures by well known scientists on modem topics of nuclear physics, where special emphasis is placed on the didactic aspects of the lectures. In the past few years, we have witnessed a rapid evolution of the field of nuclear physics towards novel directions of research. This development is accompanied by the construction of some of the largest experimental facilities ever built for nuclear research. The subjects covered by the Summer School focussed on two main issues currently under active investigation and which will be pursued with the new facilities: the transition from nucleonic to quark degrees of freedom in the decription of nuclear reactions, and the behavior of nuclear matter as one approaches extreme densities and temperatures. These topics in many respects go beyond traditional nuclear physics and the speakers therefore also included high energy physicists. From the re...

  4. NATO Advanced Study Institute on Disorder and Fracture

    CERN Document Server

    Roux, S; Guyon, E

    1990-01-01

    Fracture, and particularly brittle fracture, is a good example of an instability. For a homogeneous solid, subjected to a uniform stress field, a crack may appear anywhere in the structure once the threshold stress is reached. However, once a crack has been nucleated in some place, further damage in the solid will in most cases propagate from the initial crack, and not somewhere else in the solid. In this sense fracture is an unstable process. This property makes the process extremely sensitive to any heterogeneity present in the medium, which selects the location of the first crack nucleated. In particular, fracture appears to be very sensitive to disorder, which can favor or impede local cracks. Therefore, in most realistic cases, a good description of fracture mechanics should include the effect of disorder. Recently this need has motivated work in this direction starting from the usual description of fracture mechanics. Parallel with this first trend, statistical physics underwent a very important develop...

  5. NATO Advanced Study Institute on Sonochemistry and Sonoluminescence

    CERN Document Server

    Mason, Timothy; Reisse, Jacques; Suslick, Kenneth

    1999-01-01

    Sonochemistry is studied primarily by chemists and sonoluminescence mainly by physicists, but a single physical phenomenon - acoustic cavitation - unites the two areas. The physics of cavitation bubble collapse, is relatively well understood by acoustical physicists but remains practically unknown to the chemists. By contrast, the chemistry that gives rise to electromagnetic emissions and the acceleration of chemical reactions is familiar to chemists, but practically unknown to acoustical physicists. It is just this knowledge gap that the present volume addresses. The first section of the book addresses the fundamentals of cavitation, leading to a more extensive discussion of the fundamentals of cavitation bubble dynamics in section two. A section on single bubble sonoluminescence follows. The two following sections address the new scientific discipline of sonochemistry, and the volume concludes with a section giving detailed descriptions of the applications of sonochemistry. The mixture of tutorial lectures ...

  6. NATO Conference on Work, Organizations, and Technological Change

    CERN Document Server

    Niehaus, Richard

    1982-01-01

    This volume is the proceedings of the Symposium entitled, "Work, Organizations and Technological Change" which was held in Garmisch-Partenkirchen, West Germany, 14-19 June 1981. The meeting was sponsored by the Special Panel on Systems Sciences of the NATO Scientific Affairs Division. In proposing this meeting the Symposium Directors built upon several preceding NATO conferences in the general area of personnel systems, manpower modelling, and organization. The most recent NATO Conference, entitled "Manpower Planning and Organization Design," was held in Stresa, Italy in 1977. That meeting was organized to foster research on the interrelationships between programmatic approaches to personnel planning within organizations and behavioral science approachs to organization design. From that context of corporate planning the total internal organizational perspective was the MACRO view, and the selection, assignment, care and feeding of the people was the MICRO view. Conceptually, this meant that an integrated appr...

  7. PERSPECTIVES ON INTEROPERABILITY INTEGRATION WITHIN NATO DEFENSE PLANNING PROCESS

    Directory of Open Access Journals (Sweden)

    Florian CIOCAN

    2011-01-01

    Full Text Available Interoperability is not a new area of effort at NATO level. In fact, interoperability and more specifi cally standardization, has been a key element of the Alliance’s approach to fi elding forces for decades. But as the security and operational environment has been in a continuous change, the need to face the new threats and the current involvement in challenging operations in Afghanistan and elsewhere alongside with the necessity to interoperate at lower and lower levels of command with an increasing number of nations, including non-NATO ISAF partners, NGOs, and other organizations, have made the task even more challenging. In this respect Interoperability Integration within NATO Defense Planning Process will facilitate the timely identifi cation, development and delivery of required forces and capabilities that are interoperable and adequately prepared, equipped, trained and supported to undertake the Alliance’s full spectrum of missions.

  8. INFORMATION ASSURANCE - INTELLIGENCE - INFORMATION SUPERIORITY RELATIONSHIP WITHIN NATO OPERATIONS

    Directory of Open Access Journals (Sweden)

    Gheorghe BOARU, Ioan-Mihai ILIEŞ

    2011-01-01

    Full Text Available There is a tight relationship between information assurance, the intelligence cycle and information superiority within NATO operations. The intelligence cycle has a discrete architecture and provides on-time and relevant intelligence products to the joint force commanders and to other authorized users in a specifi c joint area of operations. The intelligence cycle must follow the evolution of the operation. A permanent intelligence estimate will be performed during the military decision making process and operations execution. Information superiority is one of the most powerful intelligence cycle achievements. and decisively infuences the success of NATO joint operations. Information superiority must be preserved and enhanced through information assurance. Information assurance is an information operation that must be planned by the military in charge of operation security or by non-military experts, executed by all personnel during the entire intelligence cycle life time and employed during the planning and execution of NATO joint operations.

  9. Findings of the NATO workshop on data fusion technologies for harbour protection

    Science.gov (United States)

    Shahbazian, Elisa; DeWeert, Michael J.; Rogova, Galina

    2006-05-01

    The NATO Security Through Science Program and the Defence Investment Division requested and sponsored the organization of a NATO Advanced Research Workshop (ARW) on the topic of Data Fusion Technologies for Harbour Protection, which was held June 27-July 1, 2005 in Tallinn, Estonia. The goal of the workshop was to help knowledge exchange between the technology experts and the security policy makers for a better understanding of goals, functions and information requirements of the decision makers as well as the way the data fusion technology can help enhancing security of harbours. In addition to presentations by experts from the research community on detection and fusion technologies as well as in practice and policy the workshop program included daily breakout sessions, in which the participants were given an opportunity to brainstorm on the topics of the workshop in interdisciplinary smaller teams. The working groups: (i) chose a scenario, including threat stages, threat types, threat methods and ranges, and response constraints due to the particular harbour environment; then (ii) identified: (a) requirements (objectives, functions and essential elements of information); (b) technologies (available and future); (c) information available and necessary through sensors and other sources, as agencies and jurisdiction; (d) methods: detection, identification, situation assessment, prediction. This paper describes the main issues and proposed approaches that were identified by the working groups.

  10. How to Brand an International Organization. NATO Case Study

    Directory of Open Access Journals (Sweden)

    Gigi Mihaita

    2011-05-01

    Full Text Available Branding products and companies has always been associated with private enterprises and less, if ever, with international intergovernmental organizations. International organizations now have a long history behind them, a history often marked by contradictory events. In the last decade the international organizations developed their own public relations department in an attempt to communicate promptly and transmit the general audience their version of reality. Having this in mind we will try to briefly present in the current work the main reasons why we believe that the international organizations, NATO in particular, have started to see themselves as brand and to create a so called “commercial identity” by becoming a brand. By applying the conceptual and analytical framework used in analyzing the marketing strategies of the private companies we will try to see whether NATO is about to become a brand. Our starting point will be a 2008 statement of Jean-François Bureau, deputy general secretary responsible with NATO’s public diplomacy: “We have the green light to think about a branding policy for NATO”. Nowadays global society, perceptions tend to become more important than reality itself, and thus positive perceptions tend to become crucial. NATO has suffered an image decline in the last decade, therefore some new communication measures tend to impose themselves. The distinction between soft power and propaganda must be carefully analyzed when we speak about branding NATO. Thus we hope to bring some necessary clarifications in the area of NATO branding. Is there a brand? Is a brand going to be constructed? How does it differ from a commercial society? Does NATO need its own TV channel? Raising questions and offering a new perspective is, in the end, our primary goal, as a debate on this subject is a must that offers a new perspective in the area of theory of international organizations.

  11. The Future of NATO and an Evolving European Security Interest

    Science.gov (United States)

    2010-03-03

    2009, p.56 30 Benjamin S. Lambeth, “NATO’s Air War for Kosovo: A strategic and Operational Assessment, Santa Monica, RAND 2001, pp. xiii -xxiv 31...Klaus Nauman, General German Army ret., Former Chief MC NATO, “Sicherheit ohne die USA? Die NATO in der Perzeption Europas “, Berichte und Studien – Die...das größere Europa ?“, Hans Arnold, Raimund Krämer, “Sicherheit für das größere Europa “, Bonn 2002, p. 355 46 François N.Heisbourg. “Europe’s

  12. Advanced low carbon-to-nitrogen ratio wastewater treatment by electrochemical and biological coupling process.

    Science.gov (United States)

    Deng, Shihai; Li, Desheng; Yang, Xue; Zhu, Shanbin; Xing, Wei

    2016-03-01

    Nitrogen pollution in ground and surface water significantly affects the environment and its organisms, thereby leading to an increasingly serious environmental problem. Such pollution is difficult to degrade because of the lack of carbon sources. Therefore, an electrochemical and biological coupling process (EBCP) was developed with a composite catalytic biological carrier (CCBC) and applied in a pilot-scale cylindrical reactor to treat wastewater with a carbon-to-nitrogen (C/N) ratio of 2. The startup process, coupling principle, and dynamic feature of the EBCP were examined along with the effects of hydraulic retention time (HRT), dissolved oxygen (DO), and initial pH on nitrogen removal. A stable coupling system was obtained after 51 days when plenty of biofilms were cultivated on the CCBC without inoculation sludge. Autotrophic denitrification, with [Fe(2+)] and [H] produced by iron-carbon galvanic cells in CCBC as electron donors, was confirmed by equity calculation of CODCr and nitrogen removal. Nitrogen removal efficiency was significantly influenced by HRT, DO, and initial pH with optimal values of 3.5 h, 3.5 ± 0.1 mg L(-1), and 7.5 ± 0.1, respectively. The ammonia, nitrate, and total nitrogen (TN) removal efficiencies of 90.1 to 95.3 %, 90.5 to 99.0 %, and 90.3 to 96.5 % were maintained with corresponding initial concentrations of 40 ± 2 mg L(-1) (NH3-N load of 0.27 ± 0.01 kg NH3-N m(-3) d(-1)), 20 ± 1 mg L(-1), and 60 ± 2 mg L(-1) (TN load of 0.41 ± 0.02 kg TN m(-3) d(-1)). Based on the Eckenfelder model, the kinetics equation of the nitrogen transformation along the reactor was N e  = N 0 exp (-0.04368 h/L(1.8438)). Hence, EBCP is a viable method for advanced low C/N ratio wastewater treatment.

  13. The Effects of Using Concept Mapping for Improving Advanced Level Biology Students' Lower- and Higher-Order Cognitive Skills

    Science.gov (United States)

    Bramwell-Lalor, Sharon; Rainford, Marcia

    2014-03-01

    This paper reports on teachers' use of concept mapping as an alternative assessment strategy in advanced level biology classes and its effects on students' cognitive skills on selected biology concepts. Using a mixed methods approach, the study employed a pre-test/post-test quasi-experimental design involving 156 students and 8 teachers from intact classes. A researcher-constructed Biology Cognitive Skills Test was used to collect the quantitative data. Qualitative data were collected through interviews and students' personal documents. The data showed that the participants utilized concept mapping in various ways and they described positive experiences while being engaged in its use. The main challenge cited by teachers was the limited time available for more consistent use. The results showed that the use of concept mapping in advanced level biology can lead to learning gains that exceed those achieved in classes where mainly traditional methods are used. The students in the concept mapping experimental groups performed significantly better than their peers in the control group on both the lower-order (F(1) = 21.508; p < .001) and higher-order (F(1) = 42.842, p < .001) cognitive items of the biology test. A mean effect size of .56 was calculated representing the contribution of treatment to the students' performance on the test items.

  14. Development of a Rapidly Deployable Special Operations Component Command (SOCC) Core Concept for the North Atlantic Treaty Organization (NATO) Special Operations Headquarters (NSHQ)

    Science.gov (United States)

    2011-12-01

    his vast “ renaissance type” knowledge in a wide array of disciplines; and the second, the most important, is his big heart. This is what makes him...operational control (OPCON) of all SOF in a designated theatre of operations. The CJFSOCC normally controls between two and six JSOTFs, SOTGs and /or...must be able to conduct NATO J1-J8 functions, advanced crisis response, time sensitive planning, and theatre - level campaign planning. It must be

  15. Proceedings of the 182nd basic science seminar (The workshop on neutron structural biology ) 'New frontiers of structural biology advanced by solution scattering'

    Energy Technology Data Exchange (ETDEWEB)

    Fujiwara, Satoru (ed.) [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2001-03-01

    182nd advanced science seminar (the workshop on neutron structural biology) was held in February 9-10, 2000 at Tokai. Thirty-six participants from universities, research institutes, and private companies took part in the workshop, and total of 24 lectures were given. This proceedings collects abstracts, the figures and tables, which the speakers used in their lectures. The proceedings contains two reviews from the point of view of x-ray and neutron scatterings, and six subjects (21 papers) including neutron and x-ray scattering in the era of structure genomics, structural changes detected with solution scattering, a new way in structural biology opened by neutron crystallography and neutron scattering, x-ray sources and detectors, simulation and solution scattering, and neutron sources and detectors. (Kazumata, Y.)

  16. Eesti NATO ukselävel / Mari-Ann Kelam

    Index Scriptorium Estoniae

    Kelam, Mari-Ann, 1946-

    2002-01-01

    Seda, et NATO liitumisläbirääkimistele kutsutavate seas on ka Eesti, saab veel tänagi pidada üheks meie iseseisva riikluse suursaavutuseks, kui mitte imeks, kirjutab Riigikogu liige Mari-Ann Kelam. Autor: Isamaaliit. Parlamendisaadik

  17. NATO palkas Coca-Colast mainekujundaja / Evelyn Kaldoja

    Index Scriptorium Estoniae

    Kaldoja, Evelyn, 1980-

    2008-01-01

    NATO otsustas oma kaubamärgi värskendamiseks palgata viimased kaks aastat Coca-Cola mainet kujundanud Michael Stopfordi, kelle põhiülesandeks tõenäoliselt jääb tavakodanikele organisatsiooni tähtsuse ja rolli selgitamine

  18. Eesti kasutas ära kõik NATO lennutunnid

    Index Scriptorium Estoniae

    2014-01-01

    Eesti on tänavu ära kasutanud kõik NATO strateegilises õhutranspordiprogrammis (SAC) ette nähtud 35 lennutundi, millega Eesti sai kasutada transpordilennukit Boeing C-17 Globemaster. Lennutunnid kulusid Eesti jalaväeüksuse tagasitoomiseks Afganistanist

  19. Estonian President : Missile Shield Should Cover All NATO Member Countries

    Index Scriptorium Estoniae

    2008-01-01

    Poola presidendi Lech Kaczynski ühepäevasest töövisiidist Eestisse. President Toomas Hendrik Ilves ja Poola riigipea kõnelesid kohtumisel Euroopa tulevikust, NATO laienemisest, Euroopa Liidu naabruspoliitikast ja energiajulgeolekust, võtsid vastu ühisdeklaratsiooni, milles kutsusid Euroopa riikide valitsusi arutama võimalust luua rahvusvaheline komisjon kommunismi inimsusevastaste kuritegude ja inimõiguste rikkumiste uurimiseks

  20. NATO Symposium on Human Detection and Diagnosis of System Failures

    CERN Document Server

    Rouse, William

    1981-01-01

    This book includes all of the papers presented at the NATO Symposium on Human Detection and Diagnosis of System Failures held at Roskilde, Denmark on August 4-8, 1980. The Symposium was sponsored by the Scientific Affairs Division of NATO and the Rise National Laboratory of Denmark. The goal of the Symposium was to continue the tradition initiated by the NATO Symposium on Monitoring Behavior and Supervisory Control held in Berchtesgaden, F .R. Germany in 1976 and the NATO Symposium on Theory and Measurement of Mental Workload held in Mati, Greece in 1977. To this end, a group of 85 psychologists and engineers coming from industry, government, and academia convened to discuss, and to generate a "state-of-the-art" consensus of the problems and solutions associated with the human IS ability to cope with the increasing scale of consequences of failures within complex technical systems. The Introduction of this volume reviews their findings. The Symposium was organized to include brief formal presentations of pape...

  1. Tweaking NATO: The Case for Integrated Multinational Divisions

    Science.gov (United States)

    2002-06-01

    environment. European Deficiencies. Technological Shortcomings. The technological gap between the United States and its NATO Allies is increasing, adversely...of the aviation electronic warfare support; both operations revealed the growing technological gap between the United States and the European allies.5

  2. NATO survey of mental health training in army recruits

    NARCIS (Netherlands)

    Adler, A.B.; Delahaij, R.; Bailey, S.M.; Berge, C. van den; Parmak, M.; Tussenbroek, B. van; Puente, J.M.; Landratova, S.; Kral, P.; Kreim, G.; Rietdijk, D.; McGurk, D.; Castro, C.A.

    2013-01-01

    To-date, there has been no international review of mental health resilience training during Basic Training nor an assessment of what service members perceive as useful from their perspective. In response to this knowledge gap, the North Atlantic Treaty Organization (NATO) Human Factors & Medicine Re

  3. Let Georgia, Ukraine into NATO now, Estonia says / Patrick Lannin

    Index Scriptorium Estoniae

    Lannin, Patrick

    2008-01-01

    Eesti president Toomas Hendrik Ilves ütles pärast Gruusiast naasmist, et Venemaa rünnak Gruusia vastu peaks NATOt veenma selles, et Gruusiale ja Ukrainale tuleks kiiresti anda NATO liikmelisus. Vabariigi President töövisiidil Gruusias 12.-13.08.2008

  4. Russia warns NATO on presence in Eastern Europe / Lorne Cook

    Index Scriptorium Estoniae

    Cook, Lorne

    2004-01-01

    Vene kaitseminister Sergei Ivanov kutsus Müncheni rahvusvahelisel julgeolekufoorumil NATO-t hoiduma kohaloleku laiendamisest Poolasse ja Balti riikidesse. USA senaator John McCain ründas Venemaad reageeringute eest, mis esitavad väljakutse naabrite demokraatlikule ja territoriaalsele terviklikkusele

  5. Wesley Clark pooldab NATO harta tugevdamist / Evi Evart

    Index Scriptorium Estoniae

    Evart, Evi

    2003-01-01

    Endine NATO vägede ülemjuhataja Euroopas Wesley Clark pidas USA välispoliitikanõukogus kõne, milles tegi ettepaneku sõlmida uus Atlandi harta ning võrdles USA suhteid Euroopa riikidega raudeesriide-aegse olukorraga

  6. Rasmussen reassures on NATO security guarantees / Rokas M. Tracevskis

    Index Scriptorium Estoniae

    Tracevskis, Rokas M.

    2009-01-01

    NATO peasekretäri Anders Fogh Rasmusseni Läti visiidist, mille käigus külastas ta Šiauliai lähedal asuvat Zokniai õhubaasi ja kohtus Leedu presidendi Dalia Grybauskaite, peaminister Andrius Kubiliuse ja välisminister Vygaudas Usackasega

  7. The Future of the Armenia-NATO Relationship

    Science.gov (United States)

    2013-03-01

    NATO-led mission in Kosovo ( KFOR ) where they continue to carry out their mission under the command of the United States. On June 16, 2005, the...part of the International Security Assistance Force in Afghanistan as well as Kosovo Force ( KFOR ). Enhancing Armenia’s participation and cooperation

  8. NATO/CCMS PILOT STUDY - CLEAN PRODUCTS AND PROCESSES

    Science.gov (United States)

    The proposed objective of the NATO/CCMS Pilot on clean products and processes is to facilitate further gains in pollution prevention, waste minimization, and design for the environment. It is anticipated that the free exchange of knowledge, experience, data, and models will fost...

  9. NATO Study of Mental Health Training in Army Recruits

    Science.gov (United States)

    2011-04-01

    many NATO nations. 6.0 REFERENCES [1] Adler, A.B., Cawkill, P., van den Berg, C., Arvers, P., Puente , J., & Cuvelier, Y. (2008...RTO-MP-HFM-205 [4] Cawkill, P., Adler, A., van den Berg, C., Avers, P., Puente , J., & Cuvelier, Y. (2006, April). The Military Leaders Survey

  10. Cracking the nodule worm code advances knowledge of parasite biology and biotechnology to tackle major diseases of livestock.

    Science.gov (United States)

    Tyagi, Rahul; Joachim, Anja; Ruttkowski, Bärbel; Rosa, Bruce A; Martin, John C; Hallsworth-Pepin, Kymberlie; Zhang, Xu; Ozersky, Philip; Wilson, Richard K; Ranganathan, Shoba; Sternberg, Paul W; Gasser, Robin B; Mitreva, Makedonka

    2015-11-01

    Many infectious diseases caused by eukaryotic pathogens have a devastating, long-term impact on animal health and welfare. Hundreds of millions of animals are affected by parasitic nematodes of the order Strongylida. Unlocking the molecular biology of representatives of this order, and understanding nematode-host interactions, drug resistance and disease using advanced technologies could lead to entirely new ways of controlling the diseases that they cause. Oesophagostomum dentatum (nodule worm; superfamily Strongyloidea) is an economically important strongylid nematode parasite of swine worldwide. The present article reports recent advances made in biology and animal biotechnology through the draft genome and developmental transcriptome of O. dentatum, in order to support biological research of this and related parasitic nematodes as well as the search for new and improved interventions. This first genome of any member of the Strongyloidea is 443 Mb in size and predicted to encode 25,291 protein-coding genes. Here, we review the dynamics of transcription throughout the life cycle of O. dentatum, describe double-stranded RNA interference (RNAi) machinery and infer molecules involved in development and reproduction, and in inducing or modulating immune responses or disease. The secretome predicted for O. dentatum is particularly rich in peptidases linked to interactions with host tissues and/or feeding activity, and a diverse array of molecules likely involved in immune responses. This research progress provides an important resource for future comparative genomic and molecular biological investigations as well as for biotechnological research toward new anthelmintics, vaccines and diagnostic tests.

  11. Global metabolic profiling and its role in systems biology to advance personalized medicine in the 21st century.

    Science.gov (United States)

    Schnackenberg, Laura K

    2007-05-01

    Systems biology attempts to elucidate the complex interaction between genes, proteins and metabolites to provide a mechanistic understanding of cellular function and how this function is affected by disease processes, drug toxicity or drug efficacy effects. Global metabolic profiling is an important component of systems biology that can be applied in both preclinical and clinical settings for drug discovery and development, and to study disease mechanisms. The metabolic profile encodes the phenotype, which is composed of the genotype and environmental factors. The phenotypic profile can be used to make decisions about the best course of treatment for an individual patient. Understanding the combined effects of genetics and environment through a systems biology framework will enable the advancement of personalized medicine.

  12. Intelligent biology and medicine in 2015: advancing interdisciplinary education, collaboration, and data science.

    Science.gov (United States)

    Huang, Kun; Liu, Yunlong; Huang, Yufei; Li, Lang; Cooper, Lee; Ruan, Jianhua; Zhao, Zhongming

    2016-01-01

    We summarize the 2015 International Conference on Intelligent Biology and Medicine (ICIBM 2015) and the editorial report of the supplement to BMC Genomics. The supplement includes 20 research articles selected from the manuscripts submitted to ICIBM 2015. The conference was held on November 13-15, 2015 at Indianapolis, Indiana, USA. It included eight scientific sessions, three tutorials, four keynote presentations, three highlight talks, and a poster session that covered current research in bioinformatics, systems biology, computational biology, biotechnologies, and computational medicine.

  13. Secondary Students' Understanding of NATO and the Warsaw Pact: The Educational Implications of Research Conducted in Three NATO Nations.

    Science.gov (United States)

    Galfo, Armand J.

    Three research projects were conducted over a three year period among secondary school students in the United Kingdom, the United States (Virginia), and West Germany in order to determine students' understanding the 40-year confrontation between the North Atlantic Treaty Organization (NATO) and the Warsaw Pact. These studies included 1991 students…

  14. NATO CCMS Workshop on Smart Materials for Energy, Communications and Security (SMECS)

    CERN Document Server

    Mezzane, Daoud

    2008-01-01

    Rapid evolution of trade, cultural and human relations provides the qualitative and quantitative enhancement of international collaborations, linking the countries with different economical and technological level. Delocalization of High-Tech industry inevitably leads to development of the material science and engineering researches in emergent countries, requiring transfer of know-how, restructuration of basic research and educational networks. This book presents the contributions of participants of the Advanced Research Workshop “Smart Materials for Energy, Communications and Security” (ARW SMECS; www.smecs.ferroix.net), organized in December 2007 in Marrakech in frame of the “NATO - Science for Peace” program. The objective of this event was the attempt to overview several hot topics of material physics related with problems of modern society: transformation and storage of energy, treatment and transmission of information, environmental security issues etc., with the focus of their implementation i...

  15. Advances in Synthetic Biology%合成生物学技术研究进展

    Institute of Scientific and Technical Information of China (English)

    吕永坤; 堵国成; 陈坚; 周景文

    2015-01-01

    Synthetic biology is an applied discipline that introduces engineering into biology. The aim of synthetic biology is to standardize and modularize biological parts. It can also be applied in the basic researches,such as the research of life origin. This review gives a detailed introduction to the synthetic biology,especially the new methods and applications.%合成生物学是一门将生物学工程化的应用学科,目的在于将生命元件标准化和模块化;也可用于生命起源等基础理论研究。对合成生物学进行了较为详细地介绍,主要综述了合成生物学领域新出现的方法及应用。

  16. Sequential ozone advanced oxidation and biological oxidation processes to remove selected pharmaceutical contaminants from an urban wastewater.

    Science.gov (United States)

    Espejo, Azahara; Aguinaco, Almudena; García-Araya, J F; Beltrán, Fernando J

    2014-01-01

    Sequential treatments consisting in a chemical process followed by a conventional biological treatment, have been applied to remove mixtures of nine contaminants of pharmaceutical type spiked in a primary sedimentation effluent of a municipal wastewater. Combinations of ozone, UVA black light (BL) and Fe(III) or Fe₃O₄ catalysts constituted the chemical systems. Regardless of the Advanced Oxidation Process (AOP), the removal of pharmaceutical compounds was achieved in 1 h of reaction, while total organic carbon (TOC) only diminished between 3.4 and 6%. Among selected ozonation systems to be implemented before the biological treatment, the application of ozone alone in the pre-treatment stage is recommended due to the increase of the biodegradability observed. The application of ozone followed by the conventional biological treatment leads high TOC and COD removal rates, 60 and 61%, respectively, and allows the subsequent biological treatment works with shorter hydraulic residence time (HRT). Moreover, the influence of the application of AOPs before and after a conventional biological process was compared, concluding that the decision to take depends on the characterization of the initial wastewater with pharmaceutical compounds.

  17. Advanced treatment of biologically pretreated coal gasification wastewater using a novel anoxic moving bed biofilm reactor (ANMBBR)-biological aerated filter (BAF) system.

    Science.gov (United States)

    Zhuang, Haifeng; Han, Hongjun; Jia, Shengyong; Zhao, Qian; Hou, Baolin

    2014-04-01

    A novel system integrating anoxic moving bed biofilm reactor (ANMBBR) and biological aerated filter (BAF) with short-cut biological nitrogen removal (SBNR) process was investigated as advanced treatment of real biologically pretreated coal gasification wastewater (CGW). The results showed the system had efficient capacity of degradation of pollutants especially nitrogen removal. The best performance was obtained at hydraulic residence times of 12h and nitrite recycling ratios of 200%. The removal efficiencies of COD, total organic carbon, NH4(+)-N, total phenols and total nitrogen (TN) were 74.6%, 70.0%, 85.0%, 92.7% and 72.3%, the corresponding effluent concentrations were 35.1, 18.0, 4.8, 2.2 and 13.6mg/L, respectively. Compared with traditional A(2)/O process, the system had high performance of NH4(+)-N and TN removal, especially under the high toxic loading. Moreover, ANMBBR played a key role in eliminating toxicity and degrading refractory compounds, which was beneficial to improve biodegradability of raw wastewater for SBNR process.

  18. NATO, From Berlin to Bosnia. Trans-Atlantic Security in Transition

    Science.gov (United States)

    1995-01-01

    since the fall of the Berlin Wall in November 1989-described at the time by a NATO officer as "the bonfire of the certainties" events in Europe have...of the Berlin Wall through the first use of NATO forces in combat in Bosnia in 1994, NATO has found itself in a race to keep up with these dramatic changes in the trans-Atlantic security environment.

  19. Venemaa teod lõid NATOs haruldase üksmeele / Evelyn Kaldoja

    Index Scriptorium Estoniae

    Kaldoja, Evelyn, 1980-

    2008-01-01

    Ilmunud ka: Postimees : na russkom jazõke 21. aug. 2008, lk. 6. Prantsusmaa välisministri Bernard Kouchneri pressikonverentsist ja NATO välisministrite otsustest Venemaaga suhtlemise osas seoses Venemaa-Gruusia sõjalise konfliktiga. USA välisministri Condoleezza Riceþi, NATO peasekretäri Jaap de Hoop Schefferi ja Eesti välisministri Urmas Paeti seisukohti. Vt. samas: Uusliikmed ootavad NATO-lt kaitseplaane; Gruusiat kurvastab OSCE vaatlejate arv

  20. Advancement in bioprocess technology: parallels between microbial natural products and cell culture biologics.

    Science.gov (United States)

    Bandyopadhyay, Arpan A; Khetan, Anurag; Malmberg, Li-Hong; Zhou, Weichang; Hu, Wei-Shou

    2017-02-09

    The emergence of natural products and industrial microbiology nearly eight decades ago propelled an era of bioprocess innovation. Half a century later, recombinant protein technology spurred the tremendous growth of biologics and added mammalian cells to the forefront of industrial producing cells in terms of the value of products generated. This review highlights the process technology of natural products and protein biologics. Despite the separation in time, there is a remarkable similarity in their progression. As the new generation of therapeutics for gene and cell therapy emerges, its process technology development can take inspiration from that of natural products and biologics.

  1. Some ozone advanced oxidation processes to improve the biological removal of selected pharmaceutical contaminants from urban wastewater.

    Science.gov (United States)

    Espejo, Azahara; Aguinaco, Almudena; Amat, Ana M; Beltrán, Fernando J

    2014-01-01

    Removal of nine pharmaceutical compounds--acetaminophen (AAF), antipyrine (ANT), caffeine (CAF), carbamazepine (CRB), diclofenac (DCF), hydrochlorothiazide (HCT), ketorolac (KET), metoprolol (MET) and sulfamethoxazole (SMX)-spiked in a primary sedimentation effluent of a municipal wastewater has been studied with sequential aerobic biological and ozone advanced oxidation systems. Combinations of ozone, UVA black light and Fe(III) or Fe3O4 constituted the chemical systems. During the biological treatment (hydraulic residence time, HRT = 24 h), only AAF and CAF were completely eliminated, MET, SMX and HCT reached partial removal rates and the rest of compounds were completely refractory. With any ozone advanced oxidation process applied, the remaining pharmaceuticals disappear in less than 10 min. Fe3O4 or Fe(III) photocatalytic ozonation leads to 35% mineralization compared to 13% reached during ozonation alone after about 30-min reaction. Also, biodegradability of the treated wastewater increased 50% in the biological process plus another 150% after the ozonation processes. Both untreated and treated wastewater was non-toxic for Daphnia magna (D. magna) except when Fe(III) was used in photocatalytic ozonation. In this case, toxicity was likely due to the ferryoxalate formed in the process. Kinetic information on ozone processes reveals that pharmaceuticals at concentrations they have in urban wastewater are mainly removed through free radical oxidation.

  2. Overview on the Role of Advance Genomics in Conservation Biology of Endangered Species.

    Science.gov (United States)

    Khan, Suliman; Nabi, Ghulam; Ullah, Muhammad Wajid; Yousaf, Muhammad; Manan, Sehrish; Siddique, Rabeea; Hou, Hongwei

    2016-01-01

    In the recent era, due to tremendous advancement in industrialization, pollution and other anthropogenic activities have created a serious scenario for biota survival. It has been reported that present biota is entering a "sixth" mass extinction, because of chronic exposure to anthropogenic activities. Various ex situ and in situ measures have been adopted for conservation of threatened and endangered plants and animal species; however, these have been limited due to various discrepancies associated with them. Current advancement in molecular technologies, especially, genomics, is playing a very crucial role in biodiversity conservation. Advance genomics helps in identifying the segments of genome responsible for adaptation. It can also improve our understanding about microevolution through a better understanding of selection, mutation, assertive matting, and recombination. Advance genomics helps in identifying genes that are essential for fitness and ultimately for developing modern and fast monitoring tools for endangered biodiversity. This review article focuses on the applications of advanced genomics mainly demographic, adaptive genetic variations, inbreeding, hybridization and introgression, and disease susceptibilities, in the conservation of threatened biota. In short, it provides the fundamentals for novice readers and advancement in genomics for the experts working for the conservation of endangered plant and animal species.

  3. Overview on the Role of Advance Genomics in Conservation Biology of Endangered Species

    Directory of Open Access Journals (Sweden)

    Suliman Khan

    2016-01-01

    Full Text Available In the recent era, due to tremendous advancement in industrialization, pollution and other anthropogenic activities have created a serious scenario for biota survival. It has been reported that present biota is entering a “sixth” mass extinction, because of chronic exposure to anthropogenic activities. Various ex situ and in situ measures have been adopted for conservation of threatened and endangered plants and animal species; however, these have been limited due to various discrepancies associated with them. Current advancement in molecular technologies, especially, genomics, is playing a very crucial role in biodiversity conservation. Advance genomics helps in identifying the segments of genome responsible for adaptation. It can also improve our understanding about microevolution through a better understanding of selection, mutation, assertive matting, and recombination. Advance genomics helps in identifying genes that are essential for fitness and ultimately for developing modern and fast monitoring tools for endangered biodiversity. This review article focuses on the applications of advanced genomics mainly demographic, adaptive genetic variations, inbreeding, hybridization and introgression, and disease susceptibilities, in the conservation of threatened biota. In short, it provides the fundamentals for novice readers and advancement in genomics for the experts working for the conservation of endangered plant and animal species.

  4. Alliansi juhi sõnul polnud NATO-Vene kohtumist kavaski / Evelyn Kaldoja

    Index Scriptorium Estoniae

    Kaldoja, Evelyn, 1980-

    2008-01-01

    NATO peasekretär Jaap de Hoop Scheffer kinnitas pärast NATO maade suursaadikuid koondava Põhja-Atlandi Nõukogu (NAC) ja Gruusiaga korraldatud NAC+1 kriisikohtumisi antud pressikonverentsil, et istungit Venemaal polnud kavaski. Jaap de Hoop Schefferi vastuseid küsimustele Venemaa jõukasutamise kohta Gruusias ja selle vastavuse kohta SRÜ rahuvalvemandaadile ning Gruusia ja Ukraina NATO-pürgimuste kohta. Vt. samas intervjuud Eesti suursaadikuga NATO juures: Jüri Luik: Medvedevi otsus sõja peatamisest NATOt ei mõjutanud

  5. Biologic

    CERN Document Server

    Kauffman, L H

    2002-01-01

    In this paper we explore the boundary between biology and the study of formal systems (logic). In the end, we arrive at a summary formalism, a chapter in "boundary mathematics" where there are not only containers but also extainers ><, entities open to interaction and distinguishing the space that they are not. The boundary algebra of containers and extainers is to biologic what boolean algebra is to classical logic. We show how this formalism encompasses significant parts of the logic of DNA replication, the Dirac formalism for quantum mechanics, formalisms for protein folding and the basic structure of the Temperley Lieb algebra at the foundations of topological invariants of knots and links.

  6. Advanced treatment of biologically pretreated coal gasification wastewater by a novel integration of catalytic ultrasound oxidation and membrane bioreactor.

    Science.gov (United States)

    Jia, Shengyong; Han, Hongjun; Zhuang, Haifeng; Xu, Peng; Hou, Baolin

    2015-01-01

    Laboratorial scale experiments were conducted to investigate a novel system integrating catalytic ultrasound oxidation (CUO) with membrane bioreactor (CUO-MBR) on advanced treatment of biologically pretreated coal gasification wastewater. Results indicated that CUO with catalyst of FeOx/SBAC (sewage sludge based activated carbon (SBAC) which loaded Fe oxides) represented high efficiencies in eliminating TOC as well as improving the biodegradability. The integrated CUO-MBR system with low energy intensity and high frequency was more effective in eliminating COD, BOD5, TOC and reducing transmembrane pressure than either conventional MBR or ultrasound oxidation integrated MBR. The enhanced hydroxyl radical oxidation, facilitation of substrate diffusion and improvement of cell enzyme secretion were the mechanisms for CUO-MBR performance. Therefore, the integrated CUO-MBR was the promising technology for advanced treatment in engineering applications.

  7. Biological Activation of Inert Ceramics: Recent Advances Using Tailored Self-Assembled Monolayers on Implant Ceramic Surfaces

    Directory of Open Access Journals (Sweden)

    Frederik Böke

    2014-06-01

    Full Text Available High-strength ceramics as materials for medical implants have a long, research-intensive history. Yet, especially on applications where the ceramic components are in direct contact with the surrounding tissue, an unresolved issue is its inherent property of biological inertness. To combat this, several strategies have been investigated over the last couple of years. One promising approach investigates the technique of Self-Assembled Monolayers (SAM and subsequent chemical functionalization to create a biologically active tissue-facing surface layer. Implementation of this would have a beneficial impact on several fields in modern implant medicine such as hip and knee arthroplasty, dental applications and related fields. This review aims to give a summarizing overview of the latest advances in this recently emerging field, along with thorough introductions of the underlying mechanism of SAMs and surface cell attachment mechanics on the cell side.

  8. Recent advances in bio-logging science: Technologies and methods for understanding animal behaviour and physiology and their environments

    Science.gov (United States)

    Evans, K.; Lea, M.-A.; Patterson, T. A.

    2013-04-01

    The deployment of an ever-evolving array of animal-borne telemetry and data logging devices is rapidly increasing our understanding of the movement, behaviour and physiology of a variety species and the complex, and often highly dynamic, environments they use and respond to. The rapid rate at which new technologies, improvements to current technologies and new analytical techniques are being developed has meant that movements, behaviour and physiological processes are being quantified at finer spatial and temporal scales than ever before. The Fourth International Symposium on Bio-logging Science, held on 14-18 March in Hobart, Australia, brought together scientists across multiple disciplines to discuss the latest innovations in technology, applications and analytical techniques in bio-logging science, building on research presented at three previous conferences. Here we present an update on the state of bio-logging research and provide some views on the future of this field of research. Papers were grouped into five theme areas: (i) Southern Ocean ecosystems; (ii) fishery and biodiversity management applications; (iii) from individuals to populations—inferences of population dynamics from individuals; (iv) conservation biology and (v) habitat modelling. Papers reflected wider uptake of newer technologies, with a greater proportion of studies utilising accelerometry and incorporating advances in statistical modelling of behaviour and habitats, especially via state space modelling methods. Environmental data collected by tags at increasing accuracies are now having wider application beyond the bio-logging community, providing important oceanographic data from regions difficult to sample using traditional methodologies. Partnerships between multiple organisations are also now enabling regional assessments of species movements, behaviour and physiology at population scales and will continue to be important for applying bio-logging technologies to species

  9. Advancements in mass spectrometry for biological samples: Protein chemical cross-linking and metabolite analysis of plant tissues

    Energy Technology Data Exchange (ETDEWEB)

    Klein, Adam [Iowa State Univ., Ames, IA (United States)

    2015-01-01

    This thesis presents work on advancements and applications of methodology for the analysis of biological samples using mass spectrometry. Included in this work are improvements to chemical cross-linking mass spectrometry (CXMS) for the study of protein structures and mass spectrometry imaging and quantitative analysis to study plant metabolites. Applications include using matrix-assisted laser desorption/ionization-mass spectrometry imaging (MALDI-MSI) to further explore metabolic heterogeneity in plant tissues and chemical interactions at the interface between plants and pests. Additional work was focused on developing liquid chromatography-mass spectrometry (LC-MS) methods to investigate metabolites associated with plant-pest interactions.

  10. 虫草属生物学研究进展%Recent Research Advances in Cordyceps Biology

    Institute of Scientific and Technical Information of China (English)

    林群英; 钟月金; 李泰辉; 沈亚恒; 宋斌

    2006-01-01

    Recent research advances in Cordyceps biology, including strain isolation and correlation with corresponding teleomorphs, fermentation studies, stroma cultivation and strain breeding, have been reviewed. Developing trends in the field have also been appraised.%论述了虫草属生物学研究包括种质分离及其与有性型关系的确定、发酵技术、子座培养和菌种选育等方面的研究进展,并展望了虫草属生物学研究的发展趋势.

  11. 'The Relation of Biology to Astronomy' and Theology: Panspermia and Panentheism; Revolutionary Convergences Advanced by Fred Hoyle and Chandra Wickramasinghe

    Science.gov (United States)

    Walker, Theodore, Jr.

    2012-06-01

    In contrast to the Copernican revolution in astro-geometry, the Hoyle-Wickramasinghe contribution to the recent and continuing revolution in astrobiology - "cometary panspermia" - features astronomy and biology converging toward theology. They employed astro-biotic reasoning (often labeled "anthropic" reasoning) to demonstrate that life is made possible by the deliberate controlling influence of the living all-embracing "intelligent universe." This is consistent with panentheism [pan-en-theos-ism, not pantheism]. As advanced by Hoyle and Wickramasinghe, cometary panspermia is panentheistic. Also, neoclassical panentheism requires generic panspermia, and favors cometary panspermia.

  12. Systems biology of yeast: enabling technology for development of cell factories for production of advanced biofuels.

    Science.gov (United States)

    de Jong, Bouke; Siewers, Verena; Nielsen, Jens

    2012-08-01

    Transportation fuels will gradually shift from oil based fuels towards alternative fuel resources like biofuels. Current bioethanol and biodiesel can, however, not cover the increasing demand for biofuels and there is therefore a need for advanced biofuels with superior fuel properties. Novel cell factories will provide a production platform for advanced biofuels. However, deep cellular understanding is required for improvement of current biofuel cell factories. Fast screening and analysis (-omics) methods and metabolome-wide mathematical models are promising techniques. An integrated systems approach of these techniques drives diversity and quantity of several new biofuel compounds. This review will cover the recent technological developments that support improvement of the advanced biofuels 1-butanol, biodiesels and jetfuels.

  13. NATO ootab kübersõja rindel järgmist kärgatust / Ahto Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Ahto, 1970-

    2008-01-01

    NATO kõrge ametniku väitel oli Eesti reaktsioon küberrünnakutele nii erakordselt tõhus, et NATO harta 5. artiklis sisalduva kollektiivkaitseklausli rakendamiseks vajadust ei tekkinud. NATO võtab vastu uue küberkaitsepoliitika ja selle rakendamise kontseptsiooni, kavandatakse kiirreageerimisabi pakkumist riikidele, kus küberrünnakute alla langevad NATO-le olulised sidevõrgud

  14. Advances and Developing Tendency of Water Use Efficiency in Plant Biology

    Institute of Scientific and Technical Information of China (English)

    CHEN Zhao-bo; TANG Jiao-wen; ZHANG Fu

    2009-01-01

    Biological water saving is one of the major fields of water saving agriculture in the future and has an enormous potential in agricultural production. In this paper, the necessity and urgency of developing high water use efficiency in plant biology were dissertated firstly, and the research progresses at home and abroad were reviewed as following aspects: mechanisms of drought resistance and high water use efficiency, criterions for identifying and evaluating drought resistance and water use efficiency, genetic improvement for drought resistance and water use efficiency, water saving irrigation technology based on the physiological regulation and control in crop plants. Major problems in the research field at present were put forward, and development tendency of water use efficiency in plant biology in the future were also discussed.

  15. Advanced studies of the biological conversion of coal synthesis gas to methane

    Energy Technology Data Exchange (ETDEWEB)

    Klasson, K.T.; Vega, J.L.; Ko, C.W.; Kimmel, D.E.; Cowger, J.P.; Barik, S.; Johnson, E.R.; Holmberg, V.L.; Clausen, E.C.; Gaddy, J.L.

    1989-11-01

    The purpose of this report is to present information obtained from experimental studies and computer-generated simulation studies aimed at demonstrating the overall technical and economic feasibility of converting the components of synthesis gas to methane using a biological processes. Many routes to methane from synthesis gas are examined, along with a variety of organisms and reactor types. The effects of important variables in the biological process are examined, including high pressure, substrate and product inhibition and sulfur gas toxicity. Mass transfer and kinetic relationships are shown for the biological systems and the overall process is then demonstrated in a bench-scale trickle bed reactor. Finally, process design and economic evaluations for various reaction schemes and reactor types are presented and discussed. 126 refs., 216 figs., 54 tabs.

  16. NATO Conference on Manpower Planning and Organization Design

    CERN Document Server

    Niehaus, Richard

    1978-01-01

    This volume is the proceedings of the conference entitled "Manpower Planning and Organization Design" which was held in Stresa, Italy, 20-24 June 1977. The Conference was sponsored by the NATO Scientific Affairs Division and organized jointly through the Special Programs Panels on Human Factors and on Systems Science. Two Conference Directors were appointed with overall responsibilities for the programme and for policy, and they were assisted in their tasks by a small advisory panel consisting of Professor A. Charnes (University of Texas), Professor W.W. Cooper (Carnegie Mellon University, now at Harvard University) and Dr. F.A. Heller (TavistQck Institute of Human Relations). Professor R. Florio of Bergamo kindly agreed to become Administrative Director and, as such, was responsible for all the local arrangements. The Conference Directors were further assisted by "national points of contact" appointed from each of the member countries of NATO. These national representatives played a substantial part in the s...

  17. On the Post-Cold War NATO Nuclear Strategy

    Institute of Scientific and Technical Information of China (English)

    Xia; Liping; Sun; Chongwen

    2014-01-01

    After the end of the Cold War, NATO’s nuclear strategy has undergone a process of evolution, so far can be divided into three phases: dissuasion strategy stage, deter war strategy stage and linkage strategy stage and similar to nuclear strategy of other nuclear-weapon states. The NATO nuclear strategy has five specific policy components: policy on statement, policy on development, policy on deployment, policy on using nuclear arms and policies on nuclear arms control. Factors impacting NATO’s nuclear strategy is multifaceted, in which strategic environment faced by NATO and NATO‘s internal debate on its major nuclear strategy are most influential, and besides the United States plays a leading role in the development of NATO’s nuclear strategy.

  18. The Working Relationships between the EU, WEU and NATO

    Directory of Open Access Journals (Sweden)

    John Roper

    1997-12-01

    Full Text Available In addressing the working relationships among the three institutions responsible for European and transatlantic relations in the field of security, it is necessary to examine why they were relatively separate until the beginning of this present decade, why they hadinitially so much difficulty in developing affective patterns of cooperation, why this is now improving, and what the prospects are for their future cooperation into the 21st century. It must be noted from the onset that some of the problems of developing effective working relationships arise from the different, albeit overlapping memberships of the European Union and NATO; and while all the full members of WEU are members of both NATO and EU, the existence of a third player cannot be said to have always been helpful.

  19. Advanced Algorithms for Rapidly Reconstructing Clandestine Releases of Biological Agents in Urban Areas

    Energy Technology Data Exchange (ETDEWEB)

    Shinn, J.H.; Hall, C.H.; Neher, L.A.; Wilder, F.J.; Gouveia, D.W.; Layton, D.W.; Daniels, J.I.

    2000-02-25

    As the United States plays a greater role in the 21st Century as global peacekeeper and international defender of human rights and democratic principles, there is an increasing likelihood that it will become the focus of acts of terrorism. Such acts of terrorism--sometimes described as ''asymmetric''--could involve the threat or use of weapons of mass destruction (WMD), particularly those considered unconventional, which include ones designed to release chemical or biological agents. In fact, biological agents are of great concern because, as noted by D.A. Henderson of the Center for Civilian Biodefense Studies at Johns Hopkins University in Baltimore, MD, ''... with shortages of hospital space, vaccines, antibiotics, there would be chaos.'' (Williams, 2000). Unfortunately, potential aggressor nations, terrorist groups, and even individuals, can, for a modest cost and effort, develop covert capabilities for manufacturing, transporting, and offensively using biological weapons of mass destruction. Furthermore, there is evidence to indicate that terrorist increasingly are targeting civilian populations--in order to inflict indiscriminate casualties--as well as other more traditional targets such as symbolic buildings or organizations (see Tucker, 1999), which suggest that introducing rapid treatment after a biological event may be more practical than concentrating on prevention (see Siegrist, 1999), especially because sensors are unlikely to be placed in all major urban areas to detect even an atmospheric biological release. For these reasons, and because symptoms for the majority of those effected may not occur or be directly identified for several days, early identification of a covert undetected biological event (CUBE) will contribute to timely medical intervention, which can save many lives.

  20. Military Presence: U.S. Personnel in NATO Europe.

    Science.gov (United States)

    1989-10-06

    Industrial Funds, and other accounts supporting the NATO presence ’Figures represent estimated civilian personnel pay costs for seven Navy commands...enma rk, ( ieria ny, Greenland, and Tu rkey. It o)perates and Comman mantins theillist fi issile earls’ w arning systeill andi sat ell ite t rack- in...many, France, and the I nited Kingdom. These personnel are students at selected civilian institutions, agencies, and industries in NXAT) European

  1. NATO Cyberspace Capability: A Strategic and Operational Evolution

    Science.gov (United States)

    2016-06-01

    Publication C4 Command, Control, Communications and Computer CCD COE Cooperative Cyber Defence Center of Excellence CDC Cyber Defence Committee CDMA ...4 Strasbourg-Kehl, France/Germany April 2-3, 2009 • Established a NATO Cyber Defence Manage- ment Authority ( CDMA ). • Improved the existing...Cyber Defence Management Authority ( CDMA ). The CDMA mission was “to initiate and co- ordinate cyber defenses, review capabilities, and con- duct

  2. A Strategic Planning Process for NATO for the 1990s

    Science.gov (United States)

    1992-06-01

    This thesis deals with the possible shifts in NATO’s strategy for the rest of the 1990s. It uses a strategic planning model to explore these possible...shift’s in strategy. Strategic planning is a systematic process of defining the mission and the objectives and creating action plans, policies and...resource allocations to achieve them. Every organization should initiate strategic planning in order to address the evolving needs of its stakeholders

  3. A Sustainable NATO/EU Partnership for the Future

    Science.gov (United States)

    2008-03-03

    decisionmaking), no duplication (of structures and resources), no discrimination (against non-EU/NATO members). 16 Gilles Rouby, Franz Pfrengle, OTAN ...Gilles Rouby, Franz Pfrengle, OTAN – Union européenne: Partenariat ou concurrence?, paragraph 3.3.2, 19. 73 Ibid, 22. 74 Federal Foreign Office... OTAN – Union européenne: Partenariat ou concurrence? which I wrote together with French Army Colonel Gilles Rouby at the Center for Higher Military

  4. Stepping Up: Burden Sharing by NATO’s Newest Members

    Science.gov (United States)

    2014-11-01

    growth had an inverse impact on military spending and was statistically significant for non-U.S. NATO allies. The 55 results were not...higher level than that of the Poles . Figure 3-3. Relative Troop Contributions of New versus Old Members to NRF 5. This case study yields mixed... earth - quake relief efforts. Since these large states had an advantage in air capability, it is again not unexpected that they contributed these

  5. NATO Enlargement: Albania, Croatia, and Possible Future Candidates

    Science.gov (United States)

    2009-04-14

    several months in 1997 after the failure of financial pyramid schemes. Since 1991, both the DPA and the other chief Albanian party, the Socialist...forces participated in SFOR, the NATO-led peacekeeping force in Bosnia , and are part of the current EU force there. Albania has deployed a company...role in Bosnia and Herzegovina, encouraging ethnic Croats there to work within the Bosnian political system rather than seek intervention by Croatia

  6. Strategic Culture and Burden Sharing in NATO: False Friends?

    Science.gov (United States)

    2012-01-01

    first, developed by Mancur Olson and Richard Zeckhauser in 1966, 14 describes security of Alliance members as a public good, and therefore defines...Alliance burden sharing as a collective action problem. Olson and Zeckhauser therefore hypothesize that NATO members with higher GDPs would contribute...theoretical perspective. First, as Olson and Zeckhauser articulated nearly 50 years ago, an alliance that includes a member that is distinctly larger and

  7. NATO: Maintaining Relevance in the Twenty-First Century

    Science.gov (United States)

    2012-06-01

    Postconflict Reconstruction .” Ethics & International Affairs (ProQuest) 23, no. 2 (Summer 2009): 121–146. Giarra, Paul. “The NATO Response Force Initiative...conceived and ill-enforced legislatures and sanctions a decade earlier.24 After World War II, in the midst of reconstructive effort for the global...ranging from collective defence to demanding stabilisation and reconstruction operations; and from security sector reform to large-scale high-intensity

  8. The Validity of Project Assessment in an Advanced Level Biology Examination.

    Science.gov (United States)

    Brown, C. R.; And Others

    1995-01-01

    Assessment of practical objectives by means of a project which occurred in an operational Advanced level examination in the United Kingdom is analyzed for construct validity. As in previous research, low correlation were found between scores of (n=218) candidates on the project and on the other components of the examination. (18 references)…

  9. Kas NATO muutub mõttetuks just nüüd? / Ron Asmus, Toomas Hendrik Ilves

    Index Scriptorium Estoniae

    Asmus, Ronald D., 1957-2011

    2004-01-01

    USA asevälisministri endine asetäitja ja nõunik NATO laienemise alal Ron Asmus ning Eesti endine välisminister, Riigikogu liige Toomas Hendrik Ilves raskustest, mis eelnesid Eesti saamisele NATO liikmeks, USA ja Euroopa suhetest, NATO tulevikust

  10. 75 FR 25910 - 60-Day Notice of Proposed Information Collection: DS-1648, Application for A, G, or NATO Visa...

    Science.gov (United States)

    2010-05-10

    ... Notice of Proposed Information Collection: DS-1648, Application for A, G, or NATO Visa, OMB No. 1405-0100... Collection: Application for A, G, or NATO Visa. OMB Control Number: 1405-0100. Type of Request: Revision of a... Number: DS-1648. Respondents: All applicants for A, G, or NATO visas reauthorizations, excluding A-3,...

  11. A novel integration of three-dimensional electro-Fenton and biological activated carbon and its application in the advanced treatment of biologically pretreated Lurgi coal gasification wastewater.

    Science.gov (United States)

    Hou, Baolin; Han, Hongjun; Zhuang, Haifeng; Xu, Peng; Jia, Shengyong; Li, Kun

    2015-11-01

    A novel integrated process with three-dimensional electro-Fenton (3D EF) and biological activated carbon (BAC) was employed in advanced treatment of biologically pretreated Lurgi coal gasification wastewater. SAC-Fe (sludge deserved activated carbon from sewage and iron sludge) and SAC (sludge deserved activated carbon) were used in 3D EF as catalytic particle electrodes (CPEs) and in BAC as carriers respectively. Results indicated that 3D EF with SAC-Fe as CPEs represented excellent pollutants and COLOR removals as well as biodegradability improvement. The efficiency enhancement attributed to generating more H2O2 and OH. The integrated process exhibited efficient performance of COD, BOD5, total phenols, TOC, TN and COLOR removals at a much shorter retention time, with the corresponding concentrations in effluent of 31.18, 6.69, 4.29, 17.82, 13.88mg/L and <20 times, allowing discharge criteria to be met. The integrated system was efficient, cost-effective and ecological sustainable and could be a promising technology for engineering applications.

  12. Advances on plant-pathogen interactions from molecular toward systems biology perspectives.

    Science.gov (United States)

    Peyraud, Rémi; Dubiella, Ullrich; Barbacci, Adelin; Genin, Stéphane; Raffaele, Sylvain; Roby, Dominique

    2016-11-21

    In the past 2 decades, progress in molecular analyses of the plant immune system has revealed key elements of a complex response network. Current paradigms depict the interaction of pathogen-secreted molecules with host target molecules leading to the activation of multiple plant response pathways. Further research will be required to fully understand how these responses are integrated in space and time, and exploit this knowledge in agriculture. In this review, we highlight systems biology as a promising approach to reveal properties of molecular plant-pathogen interactions and predict the outcome of such interactions. We first illustrate a few key concepts in plant immunity with a network and systems biology perspective. Next, we present some basic principles of systems biology and show how they allow integrating multiomics data and predict cell phenotypes. We identify challenges for systems biology of plant-pathogen interactions, including the reconstruction of multiscale mechanistic models and the connection of host and pathogen models. Finally, we outline studies on resistance durability through the robustness of immune system networks, the identification of trade-offs between immunity and growth and in silico plant-pathogen co-evolution as exciting perspectives in the field. We conclude that the development of sophisticated models of plant diseases incorporating plant, pathogen and climate properties represent a major challenge for agriculture in the future.

  13. Advanced biological treatment of aqueous effluent from the nuclear fuel cycle

    Energy Technology Data Exchange (ETDEWEB)

    Pitt, Jr., W. W.; Hancher, C. W.; Patton, B. D.; Shumate, II, S. E.

    1979-01-01

    Many of the processing steps in the nuclear fuel cycle generate aqueous effluent streams bearing contaminants that can, because of their chemical or radiological properties, pose an environmental hazard. Concentration of such contaminants must be reduced to acceptable levels before the streams can be discharged to the environment. Two classes of contaminants, nitrates and heavy metals, are addressed in this study. Specific techniques aimed at the removal of nitrates and radioactive heavy metals by biological processes are being developed, tested, and demonstrated. Although cost comparisons between biological processes and current treatment methods are presented, these comparisons may be misleading because biological processes yield environmentally better end results which are difficult to price. However, a strong case is made for the use of biological processes for removing nitrates and heavy metals fron nuclear fuel cycle effluents. The estimated costs for these methods are as low as, or lower than, those for alternate processes. In addition, the resulting disposal products - nitrogen gas, CO/sub 2/, and heavy metals incorporated into microorganisms - are much more ecologically desirable than the end products of other waste treatment methods.

  14. Recent advances in hepatitis C virus research and understanding the biology of the virus

    Institute of Scientific and Technical Information of China (English)

    Francoise Lunel-Fabiani

    2007-01-01

    @@ Since the identification of hepatitis C virus (HCV) genome in 1989[1], a lot of progresses have been done about the understanding of HCV biology, natural history and therapeutic options. HCV is a member of the Flaviviridae viral family. Its genome is a positive simple strand RNA molecule which shows significant genetic variability.

  15. Human embryonic stem cells : advancing biology and cardiogenesis towards functional applications l

    NARCIS (Netherlands)

    Braam, Stefan Robbert

    2010-01-01

    Human embryonic stem cells (hESC) hold great potential as a model for human development, disease pathology, drug discovery and safety pharmacology. All these applications will depend on comprehensive knowledge of their biology and control of their signaling mechanisms and fate choices. To begin to a

  16. NATO SET-093 joint field experiment at Bourges, France

    Science.gov (United States)

    Marty, C.; Bruel, F.; Prieur, D.; Naz, P.; Miller, L. S.

    2009-05-01

    This paper describes the NATO Task Group SET-093/RTG53/MSE (referred to as TG-53 in this report) Acoustic Detection of Weapons Firing Joint Field Experiment II conducted at the Etablissement Technique de Bourges (ETBS), Bourges, France, during 16 to 27 June 2008. This field experiment is a follow-on to the NATO TG-53 Acoustic Detection of Weapons Firing Joint Field Experiment I conducted at the Yuma Proving Grounds (YPG), Yuma, Arizona, USA, during 31 October to 4 November 2005 [1]. The objectives of the joint experiment were: (i) to collect acoustic signatures of direct and indirect firings from weapons' such as small arms, mortars, artillery, rockets, and C4 explosives, (ii) to analyze the propagation effects of grassy, wooded, and urban terrains, (iii) to share signatures collected from a variety of acoustic sensors, on the ground and in the air, distributed over a wide area, and (iv) to demonstrate the interoperability of disparate sensors developed by the various nations involved. The participating NATO countries , including France, the Netherlands, the United Kingdom, Canada, and the United States of America, and Israel as well as part of the Mediterranean dialogue countries, deployed nearly 90 sensors and sensor systems over the test range area.

  17. Advanced biological treatment of aqueous effluent from the nuclear fuel cycle

    Energy Technology Data Exchange (ETDEWEB)

    Pitt, Jr, W W; Hancher, C W; Patton, B D; Shumate, II, S E

    1980-01-01

    Many of the processing steps in the nuclear fuel cycle generate aqueous effluent streams bearing contaminants that can, because of their chemical or radiological properties, pose an environmental hazard. Concentration of such contaminants must be reduced to acceptable levels before the streams can be discharged to the environment. Two classes of contaminants, nitrates and heavy metals, are addressed in this study. Specific techniques aimed at the removal of nitrates and radioactive heavy metals by biological processes are being developed, tested, and demonstrated. Although cost comparisons between biological processes and current treatment methods will be presented, these comparisons may be misleading because biological processes yield environmentally better end results which are difficult to price. The fluidized-bed biological denitrification process is an environmentally acceptable and economically sound method for the disposal of nonreusable sources of nitrate effluents. A very high denitrification rate can be obtained in a FBR as the result of a high concentration of denitrification bacteria in the bioreactor and the stagewise operation resulting from plug flow in the reactor. The overall denitrification rate in an FBR ranges from 20- to 100-fold greater than that observed for an STR bioreactor. It has been shown that the system can be operated using Ca/sup 2 +/, Na/sup +/, or NH/sub 4//sup +/ cations at nitrate concentrations up to 1 g/liter without inhibition. Biological sorption of uranium and other radionuclides (particularly the actinides) from dilute aqueous waste streams shows considerable promise as a means of recovering these valuable resources and reducing the environmental impact, however, further development efforts are required.

  18. Assessing the application of advanced oxidation processes, and their combination with biological treatment, to effluents from pulp and paper industry.

    Science.gov (United States)

    Merayo, Noemí; Hermosilla, Daphne; Blanco, Laura; Cortijo, Luis; Blanco, Angeles

    2013-11-15

    The closure of water circuits within pulp and paper mills has resulted in a higher contamination load of the final mill effluent, which must consequently be further treated in many cases to meet the standards imposed by the legislation in force. Different treatment strategies based on advanced oxidation processes (ozonation and TiO2-photocatalysis), and their combination with biological treatment (MBR), are herein assessed for effluents of a recycled paper mill and a kraft pulp mill. Ozone treatment achieved the highest efficiency of all. The consumption of 2.4 g O3 L(-1) resulted in about a 60% COD reduction treating the effluent from the kraft pulp mill at an initial pH=7; although it only reached about a 35% COD removal for the effluent of the recycled paper mill. Otherwise, photocatalysis achieved about a 20-30% reduction of the COD for both type of effluents. In addition, the effluent from the recycled paper mill showed a higher biodegradability, so combinations of these AOPs with biological treatment were tested. As a result, photocatalysis did not report any significant COD reduction improvement whether being performed as pre- or post-treatment of the biological process; whereas the use of ozonation as post-biological treatment enhanced COD removal a further 10%, summing up a total 90% reduction of the COD for the combined treatment, as well as it also supposed an increase of the presence of volatile fatty acids, which might ultimately enable the resultant wastewater to be recirculated back to further biological treatment.

  19. Advanced models of neural networks nonlinear dynamics and stochasticity in biological neurons

    CERN Document Server

    Rigatos, Gerasimos G

    2015-01-01

    This book provides a complete study on neural structures exhibiting nonlinear and stochastic dynamics, elaborating on neural dynamics by introducing advanced models of neural networks. It overviews the main findings in the modelling of neural dynamics in terms of electrical circuits and examines their stability properties with the use of dynamical systems theory. It is suitable for researchers and postgraduate students engaged with neural networks and dynamical systems theory.

  20. Entomopathogenic organisms: conceptual advances and real-world applications for mosquito biological control

    OpenAIRE

    Samuels, Richard; Paula,Adriano; Carolino,Aline; Gomes,Simone; Paula,Catia; Cypriano,Mariana; Silva, Leila; Ribeiro, Anderson; Bastos,Jonathan; Peres, Carlos

    2016-01-01

    Richard I Samuels,1 Adriano R Paula,1 Aline T Carolino,1 Simone A Gomes,1 Catia OP Morais,1 Mariana BC Cypriano,1 Leila EI Silva,1 Anderson Ribeiro,1 Jonathan WAB Santos,1 Carlos P Silva,21Department of Entomology and Plant Pathology, State University of Norte Fluminense, Campos dos Goytacazes, Rio de Janeiro, 2Department of Biochemistry, Federal University of Santa Catarina, Florianópolis, Brazil Abstract: Recently, advances have been made in the use of entomopathogenic fungi for...

  1. [Research advances in gene polymorphisms in biological pathways of drugs for asthma].

    Science.gov (United States)

    Guo, Dan-Dan; Zheng, Xiang-Rong

    2016-06-01

    The studies on gene polymorphisms in biological pathways of the drugs for the treatment of asthma refer to the studies in which pharmacogenetic methods, such as genome-wide association studies, candidate gene studies, genome sequencing, admixture mapping analysis, and linkage disequilibrium, are used to identify, determine, and repeatedly validate the effect of one or more single nucleotide polymorphisms on the efficacy of drugs. This can provide therapeutic strategies with optimal benefits, least side effects, and lowest costs to patients with asthma, and thus realize individualized medicine. The common drugs for asthma are β2 receptor agonists, glucocorticoids, and leukotriene modifiers. This article reviews the research achievements in polymorphisms in biological pathways of the common drugs for asthma, hoping to provide guidance for pharmacogenetic studies on asthma in future and realize individualized medicine for patients with asthma soon.

  2. Recent advances in sleep-wake cycle and biological rhythms in bipolar disorder.

    Science.gov (United States)

    Robillard, Rébecca; Naismith, Sharon L; Hickie, Ian B

    2013-10-01

    The cyclical nature of periodic switches in energy, motor activation and sleep-wake cycles in bipolar disorder suggests a strong underlying relationship with disturbances in chronobiology. Current research is refining our understanding of the various patterns of sleep-wake and biological rhythms alterations at early and later stages of this illness, as well as across its depressive/fatigue, manic/hypomanic and euthymic phases. This research focuses on early detection and subsequent monitoring to predict and better manage recurrent episodes. Sleep-wake cycle and biological rhythms disturbances are also well known to affect other key aspects of physical health (notably metabolic functions), cognitive performance and elevated risks for suicide. Increasing evidence now supports the integration of behavioural or pharmacological therapeutic strategies that target the sleep-wake and circadian systems in the ongoing treatment of various phases of bipolar disorder.

  3. NATO juht: liikmete kaitse on meie põhitöö / Evelyn Kaldoja

    Index Scriptorium Estoniae

    Kaldoja, Evelyn, 1980-

    2009-01-01

    NATO peasekretär Anders Fogh Rasmussen külastas Eestit ja andis koos president Toomas Hendrik Ilvesega 8. oktoobril 2009 Kadriorus pressikonverentsi. NATO peasekretär rõhutas, et alliansi eksisteerimise põhjuseks on läbi aegade olnud ja jääb oma liikmete kaitse

  4. Anne Applebaum: Kas NATO lõpp on lähedal? / Indrek Veiserik

    Index Scriptorium Estoniae

    Veiserik, Indrek

    2009-01-01

    USA ajakirjaniku Anne Applebaumi kriitikast NATO kui organisatsiooni toimimise ja Afganistani missiooni suhtes. Kesknädala arvates võiks president Toomas Hendrik Ilves, kes on annetanud A. Applebaumile Maarjamaa Risti III klassi teenetemärgi, kuulata tema välispoliitilisi seisukohti. Viidatakse ka Kanada kindrali Rick Hillieri kriitikale NATO kohta

  5. NATO Guide for Judgement-Based Operational Analysis in Defence Decision Making : Client-Oriented Volume

    NARCIS (Netherlands)

    Wijnmalen, D.J.D.; et al

    2012-01-01

    Judgment plays an important role in all Operational Analysis (OA). NATO practitioners have determined that approaches in OA that are based on human judgement are increasingly critical to defence decision making. The purpose of the NATO Guide for Judgement-Based OA in Defence Decision Making is to cr

  6. NATO Guide for Judgement-Based Operational Analysis in Defence Decision Making : Executive Leaflet

    NARCIS (Netherlands)

    Wijnmalen, D.J.D.; et al

    2012-01-01

    Judgment plays an important role in all Operational Analysis (OA). NATO practitioners have determined that approaches in OA that are based on human judgement are increasingly critical to defence decision making. The purpose of the NATO Guide for Judgement-Based OA in Defence Decision Making is to cr

  7. Rogozin võib saada Moskva esindajaks NATO juures / Ravil Khair Al-Din

    Index Scriptorium Estoniae

    Al-Din, Ravil Khair

    2007-01-01

    Vene riigiduuma liige Dmitri Rogozini võib saada Venemaa NATO-esindajaks. Vt. samas: Mihkelson: kaks kärbest ühe hoobiga. Riigikogu EL-i asjade komisjoni esimees Marko Mihkelson nimetab kaks eesmärki, mida võib teenida Dmitri Rogozini võimalik nimetamine Venemaa NATO-esindajaks

  8. "Jazzkaar" toob NATO Pärnusse / Simmu Vasar ; interv. Kaupo Meiel

    Index Scriptorium Estoniae

    Vasar, Simmu

    2005-01-01

    Intervjuu Belgias elava ja NATO Big Bandis mängiva eesti trompetist Simmu Vasaraga. Jazzkaare ajaloost ja üritustest: läti vokaalansambli Cosmos kontserdist 24. apr. Endla teatris, Jazzkaare avakontsert-ballist 26. apr. Pärnu kontserdimajas NATO Big Bandi ja Eesti Muusikaakadeemia Big Bandiga (solistid Kaire Vilgats ja Liina Saar)

  9. Rüütel nimetas NATO, OSCE ja Euroopa Nõukogu suursaadikud

    Index Scriptorium Estoniae

    2003-01-01

    President Arnold Rüütel nimetas Harri Tiido Eesti suursaadikuks NATO juures, Alar Streimanni suursaadikuks Euroopa Nõukogu juures ja Gea Renneli alaliseks esindajaks OSCE juures. Ühtlasi kutsus president tagasi senise suursaadiku NATO juures Sulev Kannikese ja suursaadiku Euroopa Nõukogu juures Ants Froschi

  10. Adding Reports to Coalition Battle Management Language for NATO MSG-048

    NARCIS (Netherlands)

    Pullen, J.M.; Corner, D.; Singapogo, S.S.; Clarc, N.; Cordonnier, N.; Menane, M.; Khimeche, L.; Mevassvik, O.M.; Alstad, A.; Schad, U.; Frey, M.; Reus, N. M. de; Krom, P.P.J. de; Grand, N.P. le; Brook, A.

    2009-01-01

    The NATO Modeling and Simulation Group Technical Activity 48 (MSG-048) was chartered in 2006 to investigate the potential of a Coalition Battle Management Language for multinational and NATO interoperation of command and control systems with modeling and simulation. Its initial work in defining and

  11. "Die Nato hat einen grossen Fehler begangen" / Toomas Hendrik Ilves ; interv. Ansgar Graw

    Index Scriptorium Estoniae

    Ilves, Toomas Hendrik, 1953-

    2008-01-01

    Eesti president räägib sõjalistest kokkupõrgetest Gruusias, vajadusest uue rahvusvahelise julgeolekustruktuuri järele, ootustest rahvusvahelise üldsuse suhtes, Balti riikide julgeolekust ning kritiseerib NATO otsust mitte anda Gruusiale NATO liikmelisuse tegevuskava

  12. NATO ja EL lubavad tagada Kosovo ühtsuse / Ahto Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Ahto, 1970-

    2008-01-01

    NATO peasekretäri Jaap de Hoop Schefferi teatel on NATO 16 000 rahukaitsja ülesanne tagada kogu Kosovo turvalisus ja kaitsta kõiki Kosovo kodanikke. Javier Solana sõnul hakkab Euroopa Liidu tugimissioon tegutsema kogu Kosovo territooriumil

  13. 77 FR 22221 - Security Zones; North Atlantic Treaty Organization (NATO) Summit, Chicago, IL

    Science.gov (United States)

    2012-04-13

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA87 Security Zones; North Atlantic Treaty Organization (NATO... NATO Summit and associated events, which will be held in Chicago from May 16, 2012, through May 24... notice of proposed rulemaking (NPRM) entitled Security Zones; G8/North Atlantic Treaty Organization...

  14. 77 FR 74861 - Agency Information Collection Activities: Interagency Record of Request A, G, or NATO Dependent...

    Science.gov (United States)

    2012-12-18

    ... Record of Request A, G, or NATO Dependent Employment Authorization or Change/ Adjustment To/From A, G, or NATO Status, Form I-566; Extension, Without Change, of a Currently Approved Collection ACTION: 60-Day... Currently Approved Collection. (2) Title of the Form/Collection: Interagency Record of Request A, G, or...

  15. A simulation benchmark to evaluate the performance of advanced control techniques in biological wastewater treatment plants

    OpenAIRE

    Sotomayor O.A.Z.; Park S.W.; Garcia C

    2001-01-01

    Wastewater treatment plants (WWTP) are complex systems that incorporate a large number of biological, physicochemical and biochemical processes. They are large and nonlinear systems subject to great disturbances in incoming loads. The primary goal of a WWTP is to reduce pollutants and the second goal is disturbance rejection, in order to obtain good effluent quality. Modeling and computer simulations are key tools in the achievement of these two goals. They are essential to describe, predict ...

  16. Development of biological criteria for the design of advanced hydropower turbines

    Energy Technology Data Exchange (ETDEWEB)

    Cada, Glenn F. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Coutant, Charles C. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Whitney, Richard R. [Leavenworth, WA (United States)

    1997-03-01

    A review of the literature related to turbine-passage injury mechanisms suggests the following biological criteria should be considered in the design of new turbines: (1) pressure; (2) cavitation; (3) shear and turbulence; and (4) mechanical injury. Based on the study’s review of fish behavior in relation to hydropower facilities, it provides a number of recommendations to guide both turbine design and additional research.

  17. Recent advances in synthetic biology%合成生物学研究进展

    Institute of Scientific and Technical Information of China (English)

    林章凛; 张艳; 王胥; 刘鹏

    2015-01-01

    合成生物学是以工程化设计思路,构建标准化的元器件和模块,改造已存在的天然系统或者从头合成全新的人工生命体系,实现在化学品合成(包括材料、能源和天然化合物)、医学、农业、环境等领域的应用。人们利用基本的生物学元件设计和构建了基因开关、振荡器、放大器、逻辑门、计数器等合成器件,实现对生命系统的重新编程并执行特殊功能。模块化处理生物的代谢途径,并在底盘细胞上进行组装和优化,可以实现大宗化学品和精细化学品的合成。目前人们已经在丁醇、异丁醇、青蒿素和紫杉醇等化合物的生物合成上取得了重要进展。近年来还发展了多种基因组编辑和组装技术,可精确地对基因组进行编辑,人们还成功地合成了噬菌体基因组、支原体基因组和酵母基因组。在未来的50~100年内,合成生物学将对人类的医疗、化学品制造(含药品)、军事产生渐进性的、渗透性的但颠覆性的意义。%Synthetic biology is the engineering design and construction of standardized parts, devices and modules to modify the natural life systems or thede novo synthesis of new life systems. Synthetic biology has been widely applied to the fields of chemical synthesis (including materials, biofuels and natural compounds), medical industry, agriculture and environmental protection. Biological parts are used to construct synthetic modules such as toggle switch, synthetic oscillator, genetic amplifier, biologic gates and cellular counter. These synthetic modules reprogram life systems to perform specific functions. Modularized metabolic pathways are optimized in the cellular chassis to realize the biological production of bulk and fine chemicals, such as butanol, isobutanol, artemisinin, and taxol. In recent years, researchers have also developed several genome-editing and DNA assembly techniques, making it possible

  18. Next-generation sequencing as a powerful motor for advances in the biological and environmental sciences.

    Science.gov (United States)

    Faure, Denis; Joly, Dominique

    2015-04-01

    Next-generation sequencing (NGS) provides unprecedented insight into (meta)genomes, (meta)transcriptomes (cDNA) and (meta)barcodes of individuals, populations and communities of Archaea, Bacteria and Eukarya, as well as viruses. This special issue combines reviews and original papers reporting technical and scientific advances in genomics and transcriptomics of non-model species, as well as quantification and functional analyses of biodiversity using NGS technologies of the second and third generations. In addition, certain papers also exemplify the transition from Sanger to NGS barcodes in molecular taxonomy.

  19. Advanced treatment of biologically pretreated coal gasification wastewater by a novel heterogeneous Fenton oxidation process.

    Science.gov (United States)

    Zhuang, Haifeng; Han, Hongjun; Ma, Wencheng; Hou, Baolin; Jia, Shengyong; Zhao, Qian

    2015-07-01

    Sewage sludge from a biological wastewater treatment plant was converted into sewage sludge based activated carbon (SBAC) with ZnCl2 as activation agent, which was used as a support for ferric oxides to form a catalyst (FeOx/SBAC) by a simple impregnation method. The new material was then used to improve the performance of Fenton oxidation of real biologically pretreated coal gasification wastewater (CGW). The results indicated that the prepared FeOx/SBAC significantly enhanced the pollutant removal performance in the Fenton process, so that the treated wastewater was more biodegradable and less toxic. The best performance was obtained over a wide pH range from 2 to 7, temperature 30°C, 15 mg/L of H2O2 and 1g/L of catalyst, and the treated effluent concentrations of COD, total phenols, BOD5 and TOC all met the discharge limits in China. Meanwhile, on the basis of significant inhibition by a radical scavenger in the heterogeneous Fenton process as well as the evolution of FT-IR spectra of pollutant-saturated FeOx/BAC with and without H2O2, it was deduced that the catalytic activity was responsible for generating hydroxyl radicals, and a possible reaction pathway and interface mechanism were proposed. Moreover, FeOx/SBAC showed superior stability over five successive oxidation runs. Thus, heterogeneous Fenton oxidation of biologically pretreated CGW by FeOx/SBAC, with the advantages of being economical, efficient and sustainable, holds promise for engineering application.

  20. Gene expression-based biological test for major depressive disorder: an advanced study

    Directory of Open Access Journals (Sweden)

    Watanabe S

    2017-02-01

    Full Text Available Shin-ya Watanabe,1 Shusuke Numata,1 Jun-ichi Iga,2 Makoto Kinoshita,1 Hidehiro Umehara,1 Kazuo Ishii,3 Tetsuro Ohmori1 1Department of Psychiatry, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, 2Department of Neuropsychiatry, Molecules and Function, Ehime University Graduate School of Medicine, Ehime, 3Department of Applied Biological Science, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Tokyo, Japan Purpose: Recently, we could distinguished patients with major depressive disorder (MDD from nonpsychiatric controls with high accuracy using a panel of five gene expression markers (ARHGAP24, HDAC5, PDGFC, PRNP, and SLC6A4 in leukocyte. In the present study, we examined whether this biological test is able to discriminate patients with MDD from those without MDD, including those with schizophrenia and bipolar disorder.Patients and methods: We measured messenger ribonucleic acid expression levels of the aforementioned five genes in peripheral leukocytes in 17 patients with schizophrenia and 36 patients with bipolar disorder using quantitative real-time polymerase chain reaction (PCR, and we combined these expression data with our previous expression data of 25 patients with MDD and 25 controls. Subsequently, a linear discriminant function was developed for use in discriminating between patients with MDD and without MDD.Results: This expression panel was able to segregate patients with MDD from those without MDD with a sensitivity and specificity of 64% and 67.9%, respectively.Conclusion: Further research to identify MDD-specific markers is needed to improve the performance of this biological test. Keywords: depressive disorder, biomarker, gene expression, schizophrenia, bipolar disorder

  1. Polyacetylenes from terrestrial plants and fungi: Recent phytochemical and biological advances.

    Science.gov (United States)

    Negri, Roberto

    2015-10-01

    Polyacetylenes are a class of polyketides related to fatty acids that occur in plants, fungi, marine organisms and animals. These compounds show a pleiotropic profile of bioactivity, that includes antitumor, antibacterial, antimicrobial or antifungal properties. Because of this, the literature on these compounds has grown exponentially, and this review aims at summarizing the inventory of polyacetylenes occurring in terrestrial eukaryotic organisms (plants and fungi) during the last 15 years, and at discussing progress in their bioactivities and in the identification of their biological targets.

  2. NATOga ühinemine tähendab ka ühinemist NATO-Venemaa Ühisnõukoguga / Oksana Antonenko

    Index Scriptorium Estoniae

    Antonenko, Oksana

    2005-01-01

    Eesti ja NATO põhiülesandeks on kujundada strateegia NATO-Venemaa partnerluse säilitamiseks ja tugevdamiseks. NATO-Vene nõukogust. Eestile tähendab liitumine NATO-ga ka liikmestaatust NATO-Vene nõukogus, mis nõuab riigi poliitiliselt ja sõjaväliselt eliidilt läbimõtlemist, mida on Eestil pakkuda nõukogu tugevdamiseks ning selle kaalu tõstmiseks julgeolekuküsimuste lahendamisel

  3. NATOga ühinemine tähendab ka ühinemist NATO-Venemaa Ühisnõukoguga / Oksana Antonenko

    Index Scriptorium Estoniae

    Antonenko, Oksana

    2004-01-01

    Eesti ja NATO põhiülesandeks on kujundada strateegia NATO-Venemaa partnerluse säilitamiseks ja tugevdamiseks. NATO-Vene nõukogust. Eestile tähendab liitumine NATO-ga ka liikmestaatust NATO-Vene nõukogus, mis nõuab riigi poliitiliselt ja sõjaväliselt eliidilt läbimõtlemist, mida on Eestil pakkuda nõukogu tugevdamiseks ning selle kaalu tõstmiseks julgeolekuküsimuste lahendamisel

  4. 竹子分子生物学研究进展%Recent Advances in Bamboo Molecular Biology

    Institute of Scientific and Technical Information of China (English)

    姜可以; 周明兵

    2014-01-01

    Bamboo species (Poaceae: Bambusoideae) possess a distinct life history characterized by a predominance of rhizome-dependent asexual reproduction and erratic lfowering at intervals of 1 year to 120 years. Some bamboo species are of notable economic, ecological and social signiifcance throughout the World. Considerable progress has been made in bamboo research in the past few years. The advances in bamboo molecular biology since 2003 were reviewed, including the development and application of modern molecular tools in the taxonomy; the cloning and characterization of key genes involved in the critical biological processes of bamboo, such as rhizome bud development, rapid growth, flowering and stress-tolerance; the accomplishment of bamboo genome and transcriptome sequencing projects; and the establishment of genetic transformation systems. The progresses in bamboo molecular biology research provide new insights into further biological studies in Bamboo.%对2003年以来的竹子分子生物学研究进展进行了综述,包括现代分子手段在竹子分类学研究中的开发与应用,鞭芽发育、快速生长、开花、抗逆等相关的重要功能基因研究,基因组测序和转录组测序,遗传转化体系的建立等。这些为今后竹子生物学的研究提供了依据。

  5. The laminated layer: Recent advances and insights into Echinococcus biology and evolution.

    Science.gov (United States)

    Díaz, Álvaro; Fernández, Cecilia; Pittini, Álvaro; Seoane, Paula I; Allen, Judith E; Casaravilla, Cecilia

    2015-11-01

    The laminated layer is the unique mucin-based extracellular matrix that protects Echinococcus larvae, and thus to an important extent, shapes host-parasite relationships in the larval echinococcoses. In 2011, we published twin reviews summarizing what was known about this structure. Since then, important advances have been made. Complete genomes and some RNAseq data are now available for E. multilocularis and E. granulosus, leading to the inference that the E. multilocularis LL is probably formed by a single type of mucin backbone, while a second apomucin subfamily additionally contributes to the E. granulosus LL. Previously suspected differences between E. granulosus and E. multilocularis in mucin glycan size have been confirmed and pinned down to the virtual absence of Galβ1-3 chains in E. multilocularis. The LL carbohydrates from both species have been found to interact selectively with the Kupffer cell receptor expressed in rodent liver macrophages, highlighting the ancestral adaptations to rodents as intermediate hosts and to the liver as infection site. Finally, LL particles have been shown to possess carbohydrate-independent mechanisms profoundly conditioning non-liver-specific dendritic cells and macrophages. These advances are discussed in an integrated way, and in the context of the newly determined phylogeny of Echinococcus and its taenid relatives.

  6. Advances in dosimetry and biological predictors of radiation-induced esophagitis

    Science.gov (United States)

    Yu, Yang; Guan, Hui; Dong, Yuanli; Xing, Ligang; Li, Xiaolin

    2016-01-01

    Objective To summarize the research progress about the dosimetry and biological predictors of radiation-induced esophagitis. Methods We performed a systematic literature review addressing radiation esophagitis in the treatment of lung cancer published between January 2009 and May 2015 in the PubMed full-text database index systems. Results Twenty-eight eligible documents were included in the final analysis. Many clinical factors were related to the risk of radiation esophagitis, such as elder patients, concurrent chemoradiotherapy, and the intense radiotherapy regimen (hyperfractionated radiotherapy or stereotactic body radiotherapy). The parameters including Dmax, Dmean, V20, V30, V50, and V55 may be valuable in predicting the occurrence of radiation esophagitis in patients receiving concurrent chemoradiotherapy. Genetic variants in inflammation-related genes are also associated with radiation-induced toxicity. Conclusion Dosimetry and biological factors of radiation-induced esophagitis provide clinical information to decrease its occurrence and grade during radiotherapy. More prospective studies are warranted to confirm their prediction efficacy. PMID:26869804

  7. Systems biology and brain activity in neuronal pathways by smart device and advanced signal processing

    Science.gov (United States)

    Castellani, Gastone; Intrator, Nathan; Remondini, Daniel

    2014-01-01

    Contemporary biomedicine is producing large amount of data, especially within the fields of “omic” sciences. Nevertheless, other fields, such as neuroscience, are producing similar amount of data by using non-invasive techniques such as imaging, functional magnetic resonance and electroencephalography. Nowadays a big challenge and a new research horizon for Systems Biology is to develop methods to integrate and model this data in an unifying framework capable to disentangle this amazing complexity. In this paper we show how methods from genomic data analysis can be applied to brain data. In particular the concept of pathways, networks and multiplex are discussed. These methods can lead to a clear distinction of various regimes of brain activity. Moreover, this method could be the basis for a Systems Biology analysis of brain data and for the integration of these data in a multivariate and multidimensional framework. The feasibility of this integration is strongly dependent from the feature extraction method used. In our case we used an “alphabet” derived from a multi-resolution analysis that is capable to capture the most relevant information from these complex signals. PMID:25206359

  8. Gene expression-based biological test for major depressive disorder: an advanced study

    Science.gov (United States)

    Watanabe, Shin-ya; Numata, Shusuke; Iga, Jun-ichi; Kinoshita, Makoto; Umehara, Hidehiro; Ishii, Kazuo; Ohmori, Tetsuro

    2017-01-01

    Purpose Recently, we could distinguished patients with major depressive disorder (MDD) from nonpsychiatric controls with high accuracy using a panel of five gene expression markers (ARHGAP24, HDAC5, PDGFC, PRNP, and SLC6A4) in leukocyte. In the present study, we examined whether this biological test is able to discriminate patients with MDD from those without MDD, including those with schizophrenia and bipolar disorder. Patients and methods We measured messenger ribonucleic acid expression levels of the aforementioned five genes in peripheral leukocytes in 17 patients with schizophrenia and 36 patients with bipolar disorder using quantitative real-time polymerase chain reaction (PCR), and we combined these expression data with our previous expression data of 25 patients with MDD and 25 controls. Subsequently, a linear discriminant function was developed for use in discriminating between patients with MDD and without MDD. Results This expression panel was able to segregate patients with MDD from those without MDD with a sensitivity and specificity of 64% and 67.9%, respectively. Conclusion Further research to identify MDD-specific markers is needed to improve the performance of this biological test. PMID:28260899

  9. A coupled advanced oxidation-biological process for recycling industrial wastewater containing persistent organic contaminants (CADOX)

    Energy Technology Data Exchange (ETDEWEB)

    Malato, S.; Blanco, J.; Maldonado, M.I.; Alarcon, D.C.; Fernandez, P.; Oller, I.; Gernjak, W. [Platforma Solar de Almeria, CIEMAT (Spain)

    2004-07-01

    This article concentrates on coupled processes to treat seven highly water-soluble pesticides and three non-biodegradable chlorinated solvents. These are considered priority substances by the European Union and are thus the focus of some attention. The coupled processes include three oxidation processes: photocatalysis by titanium dioxide, photo-Fenton, and ozone; as well as biological degradation. The article reports on work in progress. The full project will include building two small prototypes embodying these technologies, the construction of a demonstration treatment plant based on the results obtained from the prototypes, conceptual design of a full size plant. New solar collectors were built to facilitate the photocatalysis and photo-Fenton. To date it has been determined that the photo-catalysis and photo-Fenton are suitable if the concentrations of the above contaminants is high enough. Ozone can enhance the treatment in the case of the pesticides, but not in the case of the non-biodegradable chlorinated solvents. Biotreatment is also not suitable for the solvents. The best biological system has been determined and the optimal recovery of catalyst has also been found. 5 refs., 2 tabs., 4 figs.

  10. Systems Biology and brain activity in neuronal pathways by smart device and advanced signal processing.

    Directory of Open Access Journals (Sweden)

    Gastone eCastellani

    2014-08-01

    Full Text Available Contemporary biomedicine is producing large amount of data, especially within the fields of omic sciences. Nevertheless, other fields, such as neuroscience, are producing similar amount of data by using non invasive techniques such as imaging, Functional Magnetic Resonance and Electroencephalography. Nowadays a big challenge and a new research horizon for Systems Biology is to develop methods to integrate and model this data in an unifying framework capable to disentangle this amazing complexity. In this paper we show how methods from genomic data analysis can be applied to brain data. In particular the concept of pathways, networks and multiplex are discussed. These methods can lead to a clear distinction of various regimes of brain activity. Moreover, this method could be the basis for a Systems Biology analysis of brain data and for the integration of these data in a multivariate and multidimensional framework. The feasibility of this integration is strongly dependent from the feature extraction method used. In our case we used an alphabet derived from a multi-resolution analysis that is capable to capture the most relevant information from these complex signals.

  11. Advances in dosimetry and biological predictors of radiation-induced esophagitis

    Directory of Open Access Journals (Sweden)

    Yu Y

    2016-01-01

    Full Text Available Yang Yu,1 Hui Guan,1 Yuanli Dong,1 Ligang Xing,2 Xiaolin Li2 1School of Medicine and Life Sciences, Shandong Academy of Medical Sciences, University of Jinan, Jinan, 2Department of Radiation Oncology, Shandong Cancer Hospital, Jinan, Shandong Province, People’s Republic of China Objective: To summarize the research progress about the dosimetry and biological predictors of radiation-induced esophagitis.Methods: We performed a systematic literature review addressing radiation esophagitis in the treatment of lung cancer published between January 2009 and May 2015 in the PubMed full-text database index systems.Results: Twenty-eight eligible documents were included in the final analysis. Many clinical factors were related to the risk of radiation esophagitis, such as elder patients, concurrent chemoradiotherapy, and the intense radiotherapy regimen (hyperfractionated radiotherapy or stereotactic body radiotherapy. The parameters including Dmax, Dmean, V20, V30, V50, and V55 may be valuable in predicting the occurrence of radiation esophagitis in patients receiving concurrent chemoradiotherapy. Genetic variants in inflammation-related genes are also associated with radiation-induced toxicity.Conclusion: Dosimetry and biological factors of radiation-induced esophagitis provide clinical information to decrease its occurrence and grade during radiotherapy. More prospective studies are warranted to confirm their prediction efficacy. Keywords: lung cancer, esophagitis, radiation injuries, predictors

  12. US veterinary support to standardization of food and water safety and animal care and use within NATO.

    Science.gov (United States)

    Burke, Ronald L; Mann, Kelly A; Richards, Steven; Stevenson, Timothy H

    2013-01-01

    NATO requires all standardization agreements and Al-lied Medical Publications to be reviewed at least once every 3 years to ensure they reflect current technologies and national military policies and procedures. This is particularly applicable with regard to veterinary medi-cine and food and water safety where advances in scientific knowledge and practices may result in documents quickly becoming obsolete. Such is the case with the 8 standardization agreements for which the FWSVS has responsibility; all are currently undergoing major revisions. With each revision, national representatives, including US veterinary and preventive medicine personnel, must review the documents to ensure there are no significant issues which would prevent ratification and implementation. This improves standardization and enhances interoperability between NATO partners to minimize duplication. This is accomplished by leveraging other national military capabilities, while maintaining confidence that the food, water, and veterinary support provided to their Warriors, support personnel, and animals in the field is safe and high in quality. Adherence to such standards is a major factor in maintaining the operational readiness of all alliance armed forces.

  13. ATR-FTIR spectroscopic imaging: recent advances and applications to biological systems.

    Science.gov (United States)

    Kazarian, Sergei G; Chan, K L Andrew

    2013-04-07

    Attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopic imaging is a highly versatile, label free and non-destructive chemical imaging method which can be applied to study a wide range of samples and systems. This review summarises some of the recent advances and applications of this imaging method in the area of biomedical studies, including examples of section of aorta, skin tissue and live cells. Two of the major advantages of measuring in ATR mode are the opportunity to measure samples that absorb strongly in the IR spectrum, such as aqueous systems, without significant sample preparation and the ability to increase the spatial resolution of the measured image. The implications of these advantages as well as some limitations of this imaging approach are discussed and a brief outlook at some of the possible future developments in this area is provided.

  14. Collagen-based biological glue after Appleby operation for advanced gastric cancer

    Institute of Scientific and Technical Information of China (English)

    Gianluca Baiocchi; Nazario Portolani; Federico Gheza; Stefano M Giulini

    2011-01-01

    Pancreatic fistula is a common complication of distal pancreatectomy; although various surgical procedures have been proposed, no clear advantage is evident for a single technique. We herein report the case of a 38-year-old patient affected by an advanced gastric carcinoma infiltrating the pancreas body, with extensive nodal metastases involving the celiac trunk, who underwent total gastrectomy with lymphadenectomy, distal pancreatectomy and resection en bloc of the celiac trunk (Appleby operation). At the end of the demolitive phase, thepancreaticstumpandtheaortahe pancreatic stump and the aorta at the level of the celiac ligature were covered with a layer of Tachosil(R), ahorsecollagenspongemadewitha horse collagen sponge made with human coagulation factors (fibrinogen and thrombin). Presenting this case, we wish to highlight the possible sealing effect of this product and hypothesize a role in preventing pancreatic fistula and postoperative lymphorrhagia from extensive nodal dissection.

  15. Correlation between iodine-131 MIBG imaging and biological markers in advanced neuroblastoma

    Energy Technology Data Exchange (ETDEWEB)

    Yeh, S.D.; Helson, L.; Benua, R.S.

    1988-01-01

    I-131 metaiodobenzylguanidine (MIBG) imaging was performed in 38 patients with advanced neuroblastoma. Abnormal images were found in patients with elevations of urinary vanillylmandelic acid and dopamine and high serum neuron-specific enolase levels. Normal or minimal elevation of markers was seen in patients with negative images. In follow-up studies after chemotherapy, the disappearance of abnormal uptake was noted in those patients with normal marker values. A persistently abnormal uptake occurred in patients with high marker values. Conversion from a normal image to an abnormal image also occurred in patients whose markers became elevated. I-131 MIBG imaging is sensitive in detecting active foci of a neuroblastoma and is useful in monitoring chemotherapy in these patients.

  16. Can the natural diversity of quorum-sensing advance synthetic biology?

    Science.gov (United States)

    Davis, René Michele; Muller, Ryan Yue; Haynes, Karmella Ann

    2015-01-01

    Quorum-sensing networks enable bacteria to sense and respond to chemical signals produced by neighboring bacteria. They are widespread: over 100 morphologically and genetically distinct species of eubacteria are known to use quorum sensing to control gene expression. This diversity suggests the potential to use natural protein variants to engineer parallel, input-specific, cell-cell communication pathways. However, only three distinct signaling pathways, Lux, Las, and Rhl, have been adapted for and broadly used in engineered systems. The paucity of unique quorum-sensing systems and their propensity for crosstalk limits the usefulness of our current quorum-sensing toolkit. This review discusses the need for more signaling pathways, roadblocks to using multiple pathways in parallel, and strategies for expanding the quorum-sensing toolbox for synthetic biology.

  17. Biological Matrix Effects in Quantitative Tandem Mass Spectrometry-Based Analytical Methods: Advancing Biomonitoring

    Science.gov (United States)

    Panuwet, Parinya; Hunter, Ronald E.; D’Souza, Priya E.; Chen, Xianyu; Radford, Samantha A.; Cohen, Jordan R.; Marder, M. Elizabeth; Kartavenka, Kostya; Ryan, P. Barry; Barr, Dana Boyd

    2015-01-01

    The ability to quantify levels of target analytes in biological samples accurately and precisely, in biomonitoring, involves the use of highly sensitive and selective instrumentation such as tandem mass spectrometers and a thorough understanding of highly variable matrix effects. Typically, matrix effects are caused by co-eluting matrix components that alter the ionization of target analytes as well as the chromatographic response of target analytes, leading to reduced or increased sensitivity of the analysis. Thus, before the desired accuracy and precision standards of laboratory data are achieved, these effects must be characterized and controlled. Here we present our review and observations of matrix effects encountered during the validation and implementation of tandem mass spectrometry-based analytical methods. We also provide systematic, comprehensive laboratory strategies needed to control challenges posed by matrix effects in order to ensure delivery of the most accurate data for biomonitoring studies assessing exposure to environmental toxicants. PMID:25562585

  18. Final LDRD report : development of advanced UV light emitters and biological agent detection strategies.

    Energy Technology Data Exchange (ETDEWEB)

    Figiel, Jeffrey James; Crawford, Mary Hagerott; Banas, Michael Anthony; Farrow, Darcie; Armstrong, Andrew M.; Serkland, Darwin Keith; Allerman, Andrew Alan; Schmitt, Randal L.

    2007-12-01

    We present the results of a three year LDRD project which has focused on the development of novel, compact, ultraviolet solid-state sources and fluorescence-based sensing platforms that apply such devices to the sensing of biological and nuclear materials. We describe our development of 270-280 nm AlGaN-based semiconductor UV LEDs with performance suitable for evaluation in biosensor platforms as well as our development efforts towards the realization of a 340 nm AlGaN-based laser diode technology. We further review our sensor development efforts, including evaluation of the efficacy of using modulated LED excitation and phase sensitive detection techniques for fluorescence detection of bio molecules and uranyl-containing compounds.

  19. [Molecular biology of renal cancer: bases for genetic directed therapy in advanced disease].

    Science.gov (United States)

    Maroto Rey, José Pablo; Cillán Narvaez, Elena

    2013-06-01

    There has been expansion of therapeutic options in the management of metastatic renal cell carcinoma due to a better knowledge of the molecular biology of kidney cancers. There are different tumors grouped under the term renal cell carcinoma, being clear cell cancer the most frequent and accounting for 80% of kidney tumors. Mutations in the Von Hippel-Lindau gene can be identified in up to 80% of sporadic clear cell cancer, linking a genetically inheritable disease where vascular tumors are frequent, with renal cell cancer. Other histologic types present specific alterations in molecular pathways, like c-MET in papillary type I tumors, and Fumarase Hydratase in papillary type II tumors. Identification of the molecular alteration for a specific tumor may offer an opportunity for treatment selection based on biomarkers, and, in the future, for developing an engineering designed genetic treatment.

  20. Allied Command Structures in the New NATO

    Science.gov (United States)

    1997-01-01

    Aircraft Carriers Other Surface Combatants* Attack Submarines Amphibious Ready Groups Command Ship Mobile Logistics Support** Sub Tender Maritime...29% of file enlisted personnel for the ACE Mobility Coordination Center (SHAPE). From the Regional Air Movement Coordination Center h~ Vicenza...Bosnia primarily to stop air attacks by the Serbian Air Force. 58 T H E U . S . R O L E IN A F S O U T H Advanced U.S. techonology employed

  1. A simulation benchmark to evaluate the performance of advanced control techniques in biological wastewater treatment plants

    Directory of Open Access Journals (Sweden)

    Sotomayor O.A.Z.

    2001-01-01

    Full Text Available Wastewater treatment plants (WWTP are complex systems that incorporate a large number of biological, physicochemical and biochemical processes. They are large and nonlinear systems subject to great disturbances in incoming loads. The primary goal of a WWTP is to reduce pollutants and the second goal is disturbance rejection, in order to obtain good effluent quality. Modeling and computer simulations are key tools in the achievement of these two goals. They are essential to describe, predict and control the complicated interactions of the processes. Numerous control techniques (algorithms and control strategies (structures have been suggested to regulate WWTP; however, it is difficult to make a discerning performance evaluation due to the nonuniformity of the simulated plants used. The main objective of this paper is to present a benchmark of an entire biological wastewater treatment plant in order to evaluate, through simulations, different control techniques. This benchmark plays the role of an activated sludge process used for removal of organic matter and nitrogen from domestic effluents. The development of this simulator is based on models widely accepted by the international community and is implemented in Matlab/Simulink (The MathWorks, Inc. platform. The benchmark considers plant layout and the effects of influent characteristics. It also includes a test protocol for analyzing the open and closed-loop responses of the plant. Examples of control applications in the benchmark are implemented employing conventional PI controllers. The following common control strategies are tested: dissolved oxygen (DO concentration-based control, respirometry-based control and nitrate concentration-based control.

  2. [Advances of study on prognostic factors of molecular biology in acute myeloid leukemia with normal cytogenetics].

    Science.gov (United States)

    Han, Tian-Jie; Xu, Xiao-Ping

    2010-08-01

    Acute myeloid leukemia (AML) is a group of diseases with a conspicuous heterogeneity. Following the development of cytogenetics, multiple reproducible chromosome aberrations have been discovered in AML, many of which not only are diagnostic markers for specific AML subtypes but also significant prognostic factors for determining complete remission (CR), relapse risk, and overall survival (OS). However, with the foundation of available chromosome analysis, a large group of acute myeloid leukemia (AML) patients, 40% to 49% of adults and 25% of children had not been found abnormality of chromosome karyotype under microscope. These so-called cytogenetically normal acute myeloid leukemia (CN-AML) patients have usually been classified in an intermediate-risk prognostic category. Nevertheless, the outcome of the CN-AML patients are varied in clinical studies, likely because there exist diverse gene mutations in these patients according to recent researches. Those mutations at the molecular level, on basis of which AML could be further classified, are significantly associated with CN-AML patients and offer potential targets for specific therapeutic studies. The review focuses on research advances abroad in this field including gene mutations suggesting bad prognosis such as FMS-related tyrosine kinase 3 gene mutation, Baalc gene and ETS-related gene hyperexpression, Wilms' tumor gene mutation and other gene mutations as well as gene mutations suggesting good prognosis such as nucleophosmin gene mutation, mixed lineage leukemia-partial tandem duplication, CCAAT/enhancer-binding protein α gene mutation.

  3. Polar marine biology science in Portugal and Spain: Recent advances and future perspectives

    Science.gov (United States)

    Xavier, José C.; Barbosa, Andrés; Agustí, Susana; Alonso-Sáez, Laura; Alvito, Pedro; Ameneiro, Julia; Ávila, Conxita; Baeta, Alexandra; Canário, João; Carmona, Raquel; Catry, Paulo; Ceia, Filipe; Clark, Melody S.; Cristobo, Francisco J.; Cruz, Bruno; Duarte, Carlos M.; Figuerola, Blanca; Gili, Josep-Maria; Gonçalves, Ana R.; Gordillo, Francisco J. L.; Granadeiro, José P.; Guerreiro, Miguel; Isla, Enrique; Jiménez, Carlos; López-González, Pablo J.; Lourenço, Sílvia; Marques, João C.; Moreira, Elena; Mota, Ana M.; Nogueira, Marta; Núñez-Pons, Laura; Orejas, Covadonga; Paiva, Vitor H.; Palanques, Albert; Pearson, Gareth A.; Pedrós-Alió, Carlos; Peña Cantero, Álvaro L.; Power, Deborah M.; Ramos, Jaime A.; Rossi, Sergi; Seco, José; Sañé, Elisabet; Serrão, Ester A.; Taboada, Sergi; Tavares, Sílvia; Teixidó, Núria; Vaqué, Dolors; Valente, Tiago; Vázquez, Elsa; Vieira, Rui P.; Viñegla, Benjamin

    2013-10-01

    Polar marine ecosystems have global ecological and economic importance because of their unique biodiversity and their major role in climate processes and commercial fisheries, among others. Portugal and Spain have been highly active in a wide range of disciplines in marine biology of the Antarctic and the Arctic. The main aim of this paper is to provide a synopsis of some of the results and initiatives undertaken by Portuguese and Spanish polar teams within the field of marine sciences, particularly on benthic and pelagic biodiversity (species diversity and abundance, including microbial, molecular, physiological and chemical mechanisms in polar organisms), conservation and ecology of top predators (particularly penguins, albatrosses and seals), and pollutants and evolution of marine organisms associated with major issues such as climate change, ocean acidification and UV radiation effects. Both countries have focused their polar research more in the Antarctic than in the Arctic. Portugal and Spain should encourage research groups to continue increasing their collaborations with other countries and develop multi-disciplinary research projects, as well as to maintain highly active memberships within major organizations, such as the Scientific Committee for Antarctic Research (SCAR), the International Arctic Science Council (IASC) and the Association of Polar Early Career Scientists (APECS), and in international research projects.

  4. Kosovo’s Support of NATO Stability and Humanitarian Operations

    Science.gov (United States)

    2013-12-13

    19FSK, me kapacitete per misione jashte vendit [The KSF ready for missions abroad] Telegrafi News Agency, July 1, 2012, http://www.telegrafi.com/lajme...fsk-ja-me- kapacitete-per- misione -jashte-vendit-2-23448.html (accessed September 6, 2013). 20NATO, “Statement of the North Atlantic Council,” July 9...shtyp&catid=177&Itemid=550 (accessed November 6, 2013). Telegrafi News Agency. “The KSF ready for missions abroad ( FSK, me kapacitete per misione

  5. Canary Islands (Spain): Their Importance in NATO’s Strategy.

    Science.gov (United States)

    1987-04-22

    the fact that they are now members of the same western organizations such as NATO 13 facttha the ar no memersof te sme esten oganiatins uch s NT’ and...and possibly from Libya; but it is confronted by a major Moroccan military presence. The conflict in the Western Sahara will probably endure because...but now is worse because of the Moroccan King’s speech claiming sovereignty over the Spanish cities of Ceuta and Melila. The Canaries feel that in the

  6. Application of the Operational Art to the NATO Air Element

    Science.gov (United States)

    1989-02-15

    1. 1 - Air Force Manual 1-1. Basic Aerospace Doctrina e the United States Air Force (Washington D. C.. HO U. S. Air Fsrce, 1987). p. 7-4). 14 NATO...TRAZOC. F1 Monroe . VA April 1959). p. L-7. 47 "Army Picks ADATS," p. Il. 4e Interview with COL Steve Kempf. Director f Cz.nect- Develapment...Military Operations: U.S. Armv Operational Concept for Combined Arms Air Defense. Ft. Monroe : HO TRADOC, 1988. OTHER SOURCES Air Defense Artillery

  7. Biological assessment of bisphenol A degradation in water following direct photolysis and UV advanced oxidation.

    Science.gov (United States)

    Chen, Pei-Jen; Linden, Karl G; Hinton, David E; Kashiwada, Shosaku; Rosenfeldt, Erik J; Kullman, Seth W

    2006-11-01

    Endocrine disrupting compounds (EDCs) are exogenous environmental chemicals that can interfere with normal hormone function and present a potential threat to both environmental and human health. The fate, distribution and degradation of EDCs is a subject of considerable investigation. To date, several studies have demonstrated that conventional water treatment processes are ineffective for removal of most EDCs and in some instances produce multiple unknown transformation products. In this study we have investigated the use of direct photolysis with low-pressure (LP) Hg UV lamps and UV+hydrogen peroxide (H(2)O(2)) advanced oxidation process (AOP) for the degradation of a prototypic endocrine disrupter, bisphenol A (BPA), in laboratory water. Removal rates of BPA and formation of degradation products were determined by high performance liquid chromatography (HPLC) analysis. Changes in estrogenic activity were evaluated using both in vitro yeast estrogen screen (YES) and in vivo vitellogenin (VTG) assays with Japanese medaka fish (Oryzias latipes). Our results demonstrate that UV alone did not effectively degrade BPA. However, UV in combination with H(2)O(2) significantly removed BPA parent compound and aqueous estrogenic activity in vitro and in vivo. Removal rates of in vivo estrogenic activity were significantly lower than those observed in vitro, demonstrating differential sensitivities of these bioassays and that certain UV/AOP metabolites may retain estrogenic activity. Furthermore, the UV/H(2)O(2) AOP was effective for reducing larval lethality in treated BPA solutions, suggesting BPA degradation occurred and that the degradation process did not result in the production of acutely toxic intermediates.

  8. Recent advances in alveolar biology: evolution and function of alveolar proteins.

    Science.gov (United States)

    Orgeig, Sandra; Hiemstra, Pieter S; Veldhuizen, Edwin J A; Casals, Cristina; Clark, Howard W; Haczku, Angela; Knudsen, Lars; Possmayer, Fred

    2010-08-31

    This review is focused on the evolution and function of alveolar proteins. The lung faces physical and environmental challenges, due to changing pressures/volumes and foreign pathogens, respectively. The pulmonary surfactant system is integral in protecting the lung from these challenges via two groups of surfactant proteins - the small molecular weight hydrophobic SPs, SP-B and -C, that regulate interfacial adsorption of the lipids, and the large hydrophilic SPs, SP-A and -D, which are surfactant collectins capable of inhibiting foreign pathogens. Further aiding pulmonary host defence are non-surfactant collectins and antimicrobial peptides that are expressed across the biological kingdoms. Linking to the first symposium session, which emphasised molecular structure and biophysical function of surfactant lipids and proteins, this review begins with a discussion of the role of temperature and hydrostatic pressure in shaping the evolution of SP-C in mammals. Transitioning to the role of the alveolus in innate host defence we discuss the structure, function and regulation of antimicrobial peptides, the defensins and cathelicidins. We describe the recent discovery of novel avian collectins and provide evidence for their role in preventing influenza infection. This is followed by discussions of the roles of SP-A and SP-D in mediating host defence at the alveolar surface and in mediating inflammation and the allergic response of the airways. Finally we discuss the use of animal models of lung disease including knockouts to develop an understanding of the role of these proteins in initiating and/or perpetuating disease with the aim of developing new therapeutic strategies.

  9. Application of classification methods in assessment of NATO member countries' economic, security and political risks

    Science.gov (United States)

    Odehnal, Jakub

    2013-10-01

    The aim of this paper is to attempt possible quantification of determinants of military expenditure and their application to current NATO member countries. To analyse the economic, security and political risks of NATO member countries, author employ multivariate statistical techniques which take into consideration the multivariate properties of the data sets used as input variables. Classification of countries based on cluster analysis has made it possible to identify disparities between NATO member countries, and thus to describe diverse economic or security environment affecting the amount of military expenditure as a percentage of the respective countries' gross domestic product.

  10. NATO Symposium on Women and the World of Work

    CERN Document Server

    1982-01-01

    From August 4 to 8, 1980, the Science Committee of the North Atlantic Treaty Organization (NATO) sponsored the symposium, "Women and the World of Work," which was held at the Hotel Sintra Estoril in the coastal area south of Lisbon, Portugal. This symposium hatl been "in progress" since 1977 when the idea to prepare a proposal for a NATO­ sponsored symposium on the topic of women and the military was first suggested by Dr. Walter Wilkins, then Scientific Director of the Naval Health Research Center, San Diego, California. At that time and during the previous 5 years, increasing numbers of women were being recruited into military service not only in the United States but also in several NATO-allied countries. Few research projects on the utilization of women in the military had been reported in the scientific literature with the exception of work conducted at the University of Chicago and Naval Health Research Center. Several investigators, however, were identified who had recently initiated research in this ...

  11. Towards a European Defense Identity Compatible with NATO

    Directory of Open Access Journals (Sweden)

    Rafael Estrella

    1997-12-01

    Full Text Available The European Security and Defense Identity (ESDI is a common but not defined goal, due to disagreements among Europeans on its political content. Reasons to explain this are related to the resistance to the idea of a European defense authority, fears of German hegemony, and the conviction that Europe is uncapable of defending herselfwithout the assistance of the United States. Estrella states that, with the end of the Cold War, some arguments opposing ESDI lost weight. However, the evolution and restructuring of NATO is not the product of European initiative, but rather an element of the U.S.strategy in Europe. Moreover, while the U.S. has a global strategy, Europe has not yet defined its security interests neither globally nor regionally. The author reviews the steps undertaken by NATO and the WEU towards further collaboration and the development of a European identity. He wonders whether there is enough political will either in Europe or the U.S. to overcome archaic views on trans-atlantic relations and narrow concepts about the future of Europe.

  12. Consultation and cooperation in NATO: nuclear planning, 1975-1987

    Energy Technology Data Exchange (ETDEWEB)

    Chernoff, F.B.

    1987-01-01

    This study looks at three types of explanation of international cooperation, which deal in different ways with communication and consultation. Themost-general theoretical explanation contrasts recent realist theories, like those of Waltz and Gilpin, with Keohane's functional theory of regimes. Secondly, the study looks at theories of information flow and processing (an element of consultation) within the alliance, like those of Deutsch and Steinbruner. Such theories explain governmental behavior using concepts like equilibrium of systems and feedback loop. Third, the study considers hypotheses that deal specifically with NATO and military alliances. The hypotheses relate alliance consultation processes to the cooperativeness of the cases' outcomes. Evidence is drawn from case studies of NATO decision-making. The cases include politically sensitive deployment issues, like the enhanced radiation warhead controversy in 1977-78 and the intermediate-range nuclear force deployment decision in 1979, and important, but less politically volatile arms-control decisions, including the 1975 option three proposal, the French plan for a conference on disarmament in Europe, approved in 1980, and the 1987 American zero-zero proposal on short- and intermediate-range nuclear forces in Europe.

  13. The EU-NATO Syndrome: Spotlight on Transatlantic Realities

    Directory of Open Access Journals (Sweden)

    Hajnalka Vincze

    2007-09-01

    Full Text Available This article examines the relations between the European Union (EU and NATO in light of both of the current, deeply unhealthy, state of the transatlantic relationship, and of its ongoing evolution. The first part is devoted to a retrospective outline of the links between European defence and the Atlantic system, which highlights the major constant features of these last sixty years, as well as the rupture points. Then, various issues, from the problem of the division of labour and the definition of the chain of command to coordination on the ground and arms procurement, are evoked as concrete examples where the same fundamental question marks emerge, again and again; all of them revolving around the concept of sovereignty – that of the Europeans vis-à-vis America. It is suggested in the article that current European dependence does not allow but superficial and/or temporary ‘progress’ in EU-NATO relations, just as is the case in the broader Euro-American relationship. As long as Europeans will not assume fully the objective of autonomy (i.e. freedom of decision and action, with all the commitments it would imply, their subjection will continue to generate increasing tensions, since this inherent imbalance is not only detrimental to Europe’s own interests, but it also excludes any reciprocity and prohibits any genuine partnership with the United States.

  14. NATO survey of mental health training in army recruits.

    Science.gov (United States)

    Adler, Amy B; Delahaij, Roos; Bailey, Suzanne M; Van den Berge, Carlo; Parmak, Merle; van Tussenbroek, Barend; Puente, José M; Landratova, Sandra; Kral, Pavel; Kreim, Guenter; Rietdijk, Deirdre; McGurk, Dennis; Castro, Carl Andrew

    2013-07-01

    To-date, there has been no international review of mental health resilience training during Basic Training nor an assessment of what service members perceive as useful from their perspective. In response to this knowledge gap, the North Atlantic Treaty Organization (NATO) Human Factors & Medicine Research & Technology Task Group "Mental Health Training" initiated a survey and interview with seven to twenty recruits from nine nations to inform the development of such training (N = 121). All nations provided data from soldiers joining the military as volunteers, whereas two nations also provided data from conscripts. Results from the volunteer data showed relatively consistent ranking in terms of perceived demands, coping strategies, and preferences for resilience skill training across the nations. Analysis of data from conscripts identified a select number of differences compared to volunteers. Subjects also provided examples of coping with stress during Basic Training that can be used in future training; themes are presented here. Results are designed to show the kinds of demands facing new recruits and coping methods used to overcome these demands to develop relevant resilience training for NATO nations.

  15. Biologic Treatments for Sports Injuries II Think Tank-Current Concepts, Future Research, and Barriers to Advancement, Part 1: Biologics Overview, Ligament Injury, Tendinopathy.

    Science.gov (United States)

    LaPrade, Robert F; Geeslin, Andrew G; Murray, Iain R; Musahl, Volker; Zlotnicki, Jason P; Petrigliano, Frank; Mann, Barton J

    2016-12-01

    Biologic therapies, including stem cells, platelet-rich plasma, growth factors, and other biologically active adjuncts, have recently received increased attention in the basic science and clinical literature. At the 2015 AOSSM Biologics II Think Tank held in Colorado Springs, Colorado, a group of orthopaedic surgeons, basic scientists, veterinarians, and other investigators gathered to review the state of the science for biologics and barriers to implementation of biologics for the treatment of sports medicine injuries. This series of current concepts reviews reports the summary of the scientific presentations, roundtable discussions, and recommendations from this think tank.

  16. From technological advances to biological understanding: The main steps toward high-precision RT in breast cancer.

    Science.gov (United States)

    Leonardi, Maria Cristina; Ricotti, Rosalinda; Dicuonzo, Samantha; Cattani, Federica; Morra, Anna; Dell'Acqua, Veronica; Orecchia, Roberto; Jereczek-Fossa, Barbara Alicja

    2016-10-01

    Radiotherapy improves local control in breast cancer (BC) patients which increases overall survival in the long term. Improvements in treatment planning and delivery and a greater understanding of BC behaviour have laid the groundwork for high-precision radiotherapy, which is bound to further improve the therapeutic index. Precise identification of target volumes, better coverage and dose homogeneity have had a positive impact on toxicity and local control. The conformity of treatment dose due to three-dimensional radiotherapy and new techniques such as intensity modulated radiotherapy makes it possible to spare surrounding normal tissue. The widespread use of dose-volume constraints and histograms have increased awareness of toxicity. Real time image guidance has improved geometric precision and accuracy, together with the implementation of quality assurance programs. Advances in the precision of radiotherapy is also based on the choice of the appropriate fractionation and approach. Adaptive radiotherapy is not only a technical concept, but is also a biological concept based on the knowledge that different types of BC have distinctive patterns of locoregional spread. A greater understanding of cancer biology helps in choosing the treatment best suited to a particular situation. Biomarkers predictive of response play a crucial role. The combination of radiotherapy with molecular targeted therapies may enhance radiosensitivity, thus increasing the cytotoxic effects and improving treatment response. The appropriateness of an alternative fractionation, partial breast irradiation, dose escalating/de-escalating approaches, the extent of nodal irradiation have been examined for all the BC subtypes. The broadened concept of adaptive radiotherapy is vital to high-precision treatments.

  17. NATO Briti peakorter kutsub Eesti kaitseväge endaga liituma / Tuuli Jõesaar

    Index Scriptorium Estoniae

    Jõesaar, Tuuli

    2013-01-01

    Suurbritannias Cornwallis toimunud NATO Briti peakorteri ARRC (Allied Rapid Reaction Corps) staabiõppusest Arrcade Fusion, kus osales ka kaks Eesti ohvitseri. Eesti kaitseväge oodatakse liituma ARRC-ga, Eesti poolt on liitumine esialgu lahtine

  18. Ühendriigid otsivad NATOs taas liitlast / Jamie Patrick Shea ; interv. Kadri Liik

    Index Scriptorium Estoniae

    Shea, Jamie Patrick

    2004-01-01

    NATO asepeasekretäri asetäitja räägib alliansi kaitseplaneerimisest, rahukaitsest, arengust, tegevusest Afganistanis, rollist Iraagis, võitlusest terrorismiga, koostööst USA-ga. Lisa: Jamie Patrick Shea

  19. A regulatory perspective of clinical trial applications for biological products with particular emphasis on Advanced Therapy Medicinal Products (ATMPs).

    Science.gov (United States)

    Jones, David R; McBlane, James W; McNaughton, Graham; Rajakumaraswamy, Nishanthan; Wydenbach, Kirsty

    2013-08-01

    The safety of trial subjects is the tenet that guides the regulatory assessment of a Clinical Trial Authorization application and applies equally to trials involving small molecules and those with biological/biotechnological products, including Advanced Therapy Medicinal Products. The objective of a regulator is to ensure that the potential risk faced by a trial subject is outweighed by the potential benefit to them from taking part in the trial. The focus of the application review is to assess whether risks have been identified and appropriate steps taken to alleviate these as much as possible. Other factors are also taken into account during a review, such as regulatory requirements, and emerging non-clinical and clinical data from other trials on the same or similar products. This paper examines the regulatory review process of a Clinical Trial Authorization application from the perspectives of Quality, Non-Clinical and Clinical Regulatory Assessors at the Medicines and Healthcare products Regulatory Agency. It should be noted that each perspective has highlighted specific issues from their individual competence and that these can be different between the disciplines.

  20. Biologic variability in plasma glucose, hemoglobin A1c, and advanced glycation end products associated with diabetes complications.

    Science.gov (United States)

    Leslie, R David G; Cohen, Robert M

    2009-07-01

    Plasma glucose plays a key role in the complications of diabetes mellitus. Hemoglobin A1c (HbA1c) and circulating concentrations of advanced glycation end products (AGEs) are central to diabetes clinical care and pathophysiology. However, there is evidence for variation between individuals in the relationship of plasma glucose to both these measures and to specific complications. The glycation gap (GG) and hemoglobin glycation index represent tools for quantitating the variability in the relationship between plasma glucose and HbA1c useful for identification of underlying mechanisms. Recent evidence demonstrates the heritability of HbA1c, the GG, and AGEs, yet not of glycated serum proteins. There has been tremendous effort devoted to identifying the heritable basis of types 1 and 2 diabetes; however, studies on the heritable contributors to these mediators of glucose effect on complications are only beginning. New evidence for normal biologic variation in the distribution of glucose into the red blood cell (RBC) intracellular compartment and RBC lifespan in people with and without diabetes represent candidates for heritable mechanisms and contributors to the rise in HbA1c with age. Taken as a whole, genetic and mechanistic evidence suggests new potential targets for complications prevention and improvement in complications risk estimation. These observations could help tilt the risk-benefit balance in glycemic control toward a more beneficial outcome.

  1. The Benefits of a Small Country as a Member of NATO

    Science.gov (United States)

    2010-04-08

    in Small States in the Post-Cold War World: Slovenia and NATO Enlargement, ed. Zlatko Sabic and Charles Bukowski (Westport, CT: Praeger Publishers...2000-2015: determinants and implications for defense planning and shaping. Santa Monica, CA: RM"D, 2001. Sabic, Zlatko and Charles Bukowski , ed...2002), xi. 4 Zlatko Sabic, 11Small States Aspiring for NATO Membership: Some Factors Influencing the Accession Process," in Sabic and Bukowski , 3

  2. NATO’s Weapons of Mass Destruction Initiative: Achievement and Challenges

    Science.gov (United States)

    2003-09-01

    Ashton Carter and David Omand , ‘Countering the Proliferation Risks: Adapting the Alliance to the New Security Environment,” NATO Review 44, no. 5...territories, as well as for NATO’s ability to conduct 14 Ashton Carter and David Omand , “Countering the...Ashton Carter and David Omand , ‘Countering the Proliferation Risks: Adapting the Alliance to the New Security Environment,” NATO Review, 44, no. 5

  3. Assessing Mission Impact of Cyberattacks: Report of the NATO IST-128 Workshop

    Science.gov (United States)

    2015-12-01

    the required data include the topology of the information technology (IT) and communication systems under consideration; the cyber vulnerabilities of...NATO Communications and Information Agency, Netherlands Pram Jain, MITRE, USA Mona Lange, University of Lübeck, Germany Cristian Vidu, National...of a workshop conducted by the North Atlantic Treaty Organization (NATO) Information Systems Technology (IST) Panel in Istanbul, Turkey, in June 2015

  4. Assessing Grand Strategies: How the EU and NATO Rock the Strategic Boat

    Science.gov (United States)

    2015-05-01

    arose. Sir Basil Henry Liddell Hart dynamically contributed to the debate by promoting the concept of grand strategy.50 However, the concept of grand...the Science of War, 105–6. Corbett, Some Principles of Maritime Strategy, 308. 58. Basil Henry Liddell Hart, Strategy, 2nd rev. ed (New York, N.Y... Moore , advocate that the NATO Strategic Concept constitutes a NATO grand strategy more ostensibly.7 These disparate analyses merely reflect the

  5. Taking the lead in professional growth the development of a NATO SOF intelligence officer

    OpenAIRE

    2012-01-01

    Approved for public release; distribution is unlimited. This thesis analyzes intelligence support to NATO Special Operations and the training that facilitates this capability and recommends a model to increase competence in the field of intelligence. The training provided by the NSTEP has led NATO SOF intelligence personnel to fill critical positions that have afforded operational elements to execute missions. The successes of ISAF SOF have been attributed to the skilled analysts that have...

  6. The South Eastern Europe Brigade: An Option for NATO-Led Peace Support Operations?

    Science.gov (United States)

    2011-06-10

    synthesize the necessary traits for conducting a successful PO mission. Plain or simple as the descriptions of NATO and US military guidance related to...significant traits of the two main subjects of this thesis, SEEBRIG, and NATO-led PSO, and the analysis of the outcomes from all steps. Evaluation...chapter VII of the UN Charter (example include UNOCI – UN Operation in Cote d‘Ivoire, MINUSTAH –UN Stabilisation Mission in Haiti, UNAMID – African

  7. The Regional Special Operations Headquarters: Franchising the NATO Model as a Hedge in Lean Times

    Science.gov (United States)

    2012-04-01

    1 AIR FORCE FELLOWS AIR UNIVERSITY THE REGIONAL SPECIAL OPERATIONS HEADQUARTERS: FRANCHISING THE NATO MODEL AS A HEDGE IN LEAN...Headquarters: Franchising The NATO Model As A Hedge In Lean Times 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d...it is not copyrighted, but is the property of the United States government. 3 The Regional Special Operations Headquarters: Franchising the

  8. Fair Share or Freeride: Burden Sharing in Post-Cold War NATO

    Science.gov (United States)

    2015-05-23

    Afghanistan. In 2012, PfP nations Austria, Morocco, Switzerland , and Ukraine all contributed larger contingents than most NATO members.92 As with...Jennifer. Going Global or Going Nowhere? NATO’s Role in Contemporary International Security. Bern, Switzerland : Peter Lang, 2008. Mihalka, Michael...Deterrent Force. Hong Kong: Concord Publications, 1992. Nurkin, Tate. “ Flagging Force? Options for the Evolution of NATO. Jane’s Intelligence Review

  9. Rapid Execution of an Analysis of Alternatives for NATO Special Operations HQ: A Smart Defence Approach

    Science.gov (United States)

    2012-12-01

    multinational force. Since becoming a multinational force, NATO has supported operations in Bosnia in the early 1990s and Kosovo in 1999 (“NATO,” n.d...RESET 0 12tl\\ CAB Direct Support 106 KFOR 14 21 otal 205 UNCLASSiflEO I FO.=t OffiCW. USE ONLY GS-t91D-12 M. M~ A. P¥Ul’l J. 8e.nl:)!l

  10. U.S. Strategic Interests and Georgias Prospects for NATO Membership

    Science.gov (United States)

    2015-03-01

    AND ABBREVIATIONS AEECA Assistance to Europe, Eurasia, and Central Asia ANP Annual National Program BRICS Brazil, Russia, India, China, and...EU member states to face off militarily against Russia. 21 Jon Hartley, “The BRICS Bank is Born Out of Politics,” Forbes, July 28, 2014, http...www.forbes.com/sites/jonhartley/2014/07/28/the- brics -bank-is-born-out-of-politics. 22 “NATO Funding,” NATO, last accessed January 28, 2015, http

  11. NATO kõrgeim sõjaväelane: olge abi vastuvõtuks valmis / Raymond Henault ; interv. Raimo Poom

    Index Scriptorium Estoniae

    Henault, Raymond

    2007-01-01

    NATO sõjalise komitee esimehe sõnul on NATO eesmärk aidata Balti riike õhuturbega kuni 2018. aastani, õhuturbe kontseptsioon vaadatakse üle 2011. aastal. Ämari lennuväli peab muutuma kättesaadavaks kõigile NATO õhuvägedele. Kindral tõstis esile küberkaitse kompetentsikeskuse loomise vajadust ning avaldas arvamust Eesti kaitseväe praeguse mudeli kohta

  12. Advances in biological dosimetry

    Science.gov (United States)

    Ivashkevich, A.; Ohnesorg, T.; Sparbier, C. E.; Elsaleh, H.

    2017-01-01

    Rapid retrospective biodosimetry methods are essential for the fast triage of persons occupationally or accidentally exposed to ionizing radiation. Identification and detection of a radiation specific molecular ‘footprint’ should provide a sensitive and reliable measurement of radiation exposure. Here we discuss conventional (cytogenetic) methods of detection and assessment of radiation exposure in comparison to emerging approaches such as gene expression signatures and DNA damage markers. Furthermore, we provide an overview of technical and logistic details such as type of sample required, time for sample preparation and analysis, ease of use and potential for a high throughput analysis.

  13. Advancing vector biology research

    NARCIS (Netherlands)

    Kohl, Alain; Pondeville, Emilie; Schnettler, Esther; Crisanti, Andrea; Supparo, Clelia; Christophides, George K.; Kersey, Paul J.; Maslen, Gareth L.; Takken, Willem; Koenraadt, Constantianus J.M.; Oliva, Clelia F.; Busquets, Núria; Abad, F.X.; Failloux, Anna Bella; Levashina, Elena A.; Wilson, Anthony J.; Veronesi, Eva; Pichard, Maëlle; Arnaud Marsh, Sarah; Simard, Frédéric; Vernick, Kenneth D.

    2016-01-01

    Vector-borne pathogens impact public health, animal production, and animal welfare. Research on arthropod vectors such as mosquitoes, ticks, sandflies, and midges which transmit pathogens to humans and economically important animals is crucial for development of new control measures that target t

  14. NATO 1949-2009: Fra regional forsvarsorganisation til global militær aktør

    DEFF Research Database (Denmark)

    Villaume, Poul

    2009-01-01

    Baggrunden for Atlantpagtens oprettelse, NATOs formative periode i 1950erne, 'out-of-area'-operationer i Den Tredje Verden, atomstrategier, afspændingsperioden, den kolde krigs afslutning, samt NATOs transformation og udvidelse efter 1991 tematiseres i en oversigtlig analyse.......Baggrunden for Atlantpagtens oprettelse, NATOs formative periode i 1950erne, 'out-of-area'-operationer i Den Tredje Verden, atomstrategier, afspændingsperioden, den kolde krigs afslutning, samt NATOs transformation og udvidelse efter 1991 tematiseres i en oversigtlig analyse....

  15. NATO ARI on Ergonomic Data for Equipment Design

    CERN Document Server

    1984-01-01

    For many years ergonomists and human engineering specialists have made significant contributions to the solution of problems faced in the area of human labour and to the introduction of their research results and field experience into the process of equipment design. However, the rapid increase in complexity of equipment in use as well as in development demonstrates the necessity of broaden­ ing the point of view continuously. The workshop held in Munich from March 22nd to March 26th, 1982, was an excellent opportunity for the participants to discuss their respective interests and their interpretation of needs for future research. The workshop was sponsored by the Human Factors Special Programme Panel of the Scientific Affairs Division of NATO. This sponsorship, together with the helpful assistance rendered by Drs. Bayraktar, Kroemer, and Sanders, is gratefully acknowledged. This volume contains the papers presented during the workshop. All these papers are directly related to the general aim: the ex­ chang...

  16. Russian influence on NATO member/non-member relationships : a case study of the US-Ukraine military to military relationship

    OpenAIRE

    Righello, Joseph D.

    2002-01-01

    Approved for public release; distribution in unlimited. This thesis explores Russia's attempts to influence NATO bilateral relationships between members and non-members (partners) and examines the US-Ukraine military-to-military program as its case study. The thesis begins by describing Russia's relations with NATO, centering on NATO enlargement and its role in the NATO-Russia relationship. It then examines the US-Ukraine relationship, with a specific eye toward military-to-military relati...

  17. Telemedicine deployments within NATO military forces: a data analysis of current and projected capabilities.

    Science.gov (United States)

    Lam, David M; Poropatich, Ronald K

    2008-11-01

    Since the creation of the NATO Telemedicine Expert Panel (now renamed the TMED Expert Team) in 2000, when few nations had deployed telemedicine systems to support military field operations, this group has been encouraging the nations to deploy telemedicine (TMED) in support of their forces, and to write the use of TMED into NATO doctrine. This has been a relatively successful effort, and TMED is increasingly being used within the military medical structures of some NATO and Partnership for Peace nations to provide medical care to deployed military personnel. We report the results of a multinational survey of current and projected availability of various telemedicine modalities within the NATO medical services that are participating in the work of the TMED expert team (ET). Though only a "snapshot in time," and not representing all NATO nations, this is the first attempt to identify both current and planned TMED utilization within the multinational military medical community. Participating nations report that communication systems now in place at the lowest levels of medical support increasingly enable the routine use of Web-based teleconsultation modalities. Teleradiology is now being seen as the de facto standard for imaging support. While a number of nations report they have deployed capabilities for obtaining clinical consultations at a distance, most responding nations do not have a formal organizational structure to control and manage remote consultation and rely on informal clinical relationships (e.g., requesting consults from the deployed clinician's home hospital or from friends). Military electronic health records are in use by only a minority of nations and fewer still are capable of civilian interface. Less common TMED capabilities (e.g., tele-microbiology, tele-pathology, tele-medical maintenance) are being increasingly used, but are still rarely deployed. As a result of the findings of this survey, specific recommendations for expanding the use of

  18. Gastric cancer: a primer on the epidemiology and biology of the disease and an overview of the medical management of advanced disease.

    Science.gov (United States)

    Shah, Manish A; Kelsen, David P

    2010-04-01

    Gastric cancer is a cause of significant morbidity and cancer-related mortality worldwide. Despite recent advances in targeted therapy and understanding of the biology and development of the malignancy, progress in the treatment of gastric cancer has been limited. Most newly diagnosed patients will present with incurable disease, and have a median survival of less than 1 year. Although the disease has widespread ethnic and epidemiologic differences, medical management of gastric cancer does not distinguish among the various disease subtypes. The recent report of the ToGA phase III study has validated Her2 as a molecular target in this disease, supporting the concept that a greater understanding of the biology of gastric cancer subsets may improve treatment selection and overall outcome of individual patients. This article summarizes the epidemiology and ethnic variation of this disease to crystalize subtypes of gastric cancer in the context of current and future medical management of advanced disease.

  19. Advances in the biology and therapy of chronic myeloid leukemia (CML): Proceedings from the 6th Post-ASH International CML and Myeloproliferative Neoplasms Workshop

    Science.gov (United States)

    Van Etten, Richard A.; Mauro, Michael; Radich, Jerald P.; Goldman, John M.; Saglio, Giuseppe; Jamieson, Catriona; Soverini, Simona; Gambacorti-Passerini, Carlo; Hehlmann, Rüdiger; Martinelli, Giovanni; Perrotti, Danilo; Scadden, David T.; Skorski, Tomasz; Tefferi, Ayalew; Mughal, Tariq I.

    2012-01-01

    Following the 53rd annual meeting of the American Society of Hematology in San Diego in December 2011, a group of clinical and laboratory investigators convened for the 6th post-ASH International Workshop on chronic myeloid leukemia (CML) and myeloproliferative neoplasms (MPN). The workshop took place on the 13th–14th December at the Estancia, La Jolla, California, USA. This report summarizes the most recent advances in the biology and therapy of CML that were presented at ASH and discussed at the Workshop. Preclinical studies focused on the CML stem cell and its niche, and on early results of deep sequencing of CML genomes. Clinical advances include updates on 2nd and 3rd generation TKIs, molecular monitoring, TKI discontinuation studies, and new therapeutic agents. A report summarizing the pertinent advances in MPN has been published separately. PMID:23121619

  20. 75 FR 57543 - 30-Day Notice of Proposed Information Collection: DS-1648, Application for A, G, or NATO Visa...

    Science.gov (United States)

    2010-09-21

    ... Notice of Proposed Information Collection: DS-1648, Application for A, G, or NATO Visa, OMB No. 1405-0100.... Title of Information Collection: Application for A, G, or NATO Visa. OMB Control Number: 1405-0100. Type... Affairs, Office of Visa Services. Form Number: DS-1648. Respondents: All applicants for A, G, or...

  1. NATO and Russia. Grade 10 Lesson. Schools of California Online Resources for Education (SCORE): Connecting California's Classrooms to the World.

    Science.gov (United States)

    Fix, Terry

    This lesson plan imagines the student as part of a delegation to a special meeting of the North Atlantic Treaty Organization (NATO)-sponsored Euro-Atlantic Partnership Council being held in Brussels, Belgium, where the topic of discussion is a proposal by several NATO members to invite independent republics of the former Soviet Union to become…

  2. NATO Expansion: Romania and Bulgaria within the Larger Context. Fulbright-Hays Summer Seminars Abroad, 1997. (Romania and Bulgaria).

    Science.gov (United States)

    Leonard, Thomas M.

    This paper analyzes the issues regarding current expansion of NATO membership to include Romania and Bulgaria. The perspective given is that of the United States and places the Romanian and Bulgarian cases within the context of those issues. Sections of the paper include: (1) "The Road to Madrid: Expansion of NATO"; (2) "No Easy…

  3. Lynx multi-mode SAR in support of NATO Unified Vision 2012 trial

    Science.gov (United States)

    Dunkel, R.; Verge, T.; Linnehan, R.; Doerry, A.

    2013-05-01

    In June 2012, General Atomics Aeronautical Systems, Inc. (GA-ASI) Reconnaissance Systems Group participated in the NATO Unified Vision 2012 (UV12) Joint ISR (JISR) Trial at Orland Main Air Station in Brekstad, Norway. GA-ASI supplied a modified King Air 200 as a Predator B/MQ-9 Reaper Remotely Piloted Aircraft (RPA) surrogate outfitted with a Lynx Block 30 Multi-mode Synthetic Aperture Radar/Ground Moving Target Indicator (SAR/GMTI), a FLIR Star SAFIRE 3800HD Electro-optical/Infrared (EO/IR) sensor, and a L-3 Tactical Common Data Link. This airborne platform was combined with GA-ASI's new System for Tactical Archival, Retrieval, and Exploitation (STARE) for full integration into the NATO ISR exploitation community. UV12 was an event sponsored by the NATO Joint Capability Group on Intelligence, Surveillance, and Reconnaissance (ISR) to focus on the interoperability of national ISR assets and improving JISR concept of operations. The Predator B RPA surrogate flew alongside multiple NATO ISR assets in nine missions that showcased the platform's all-weather ISR capabilities focusing on the Lynx SAR/GMTI and Maritime Wide Area Search (MWAS) modes. The inclusion of the STARE technology allowed GA-ASI's radar and Full Motion Video (FMV) data to be seamlessly processed and passed to joint networks where the data was fused with other NATO ISR products, resulting in a full battlefield reconnaissance picture.

  4. INTERCONNECTING NETWORKS WITH DIFFERENT LEVELS OF SECURITY – A PRESENT NATO PROBLEM

    Directory of Open Access Journals (Sweden)

    LIVIU TATOMIR

    2016-07-01

    Full Text Available A situation often met in the Romanian Armed Forces in recent years is the need for interconnecting two networks (domains with different levels of classification. Considering that the Romanian armed troops are involved in numerous missions with NATO partners, solutions, already implemented across the organization, are considered to be applied in domestic systems, also. This paper presents the solutions adopted by NATO in order to solve the problem of cross -domains interconnections. We present the maturity level reached by these solutions and the possibility of implementing these solutions in the Romanian Armed Forces, with or without specific adaptation to our own rules and regulations. The goal is to use a NATO already proved solution to our national classified networks.

  5. The role of differentiation and standards-based grading in the science learning of struggling and advanced learners in a detracked high school honors biology classroom

    Science.gov (United States)

    MacDonald, Michelina Ruth Carter

    The accountability movement in education resulting from the passage of The No Child Left Behind Act of 2001 has brought to light the disparities that exist in student achievement in the United States which play out along racial and socioeconomic lines. Three educational practices hold promise for reducing this achievement gap: differentiated instruction, standards-based assessment, and elimination of academic tracking. The purpose of this practitioner research study was to examine the ways that differentiation and standards-based assessment can support struggling learners and challenge advanced learners in a detracked, honors biology classroom. To gain insight into the role that differentiation and standards-based assessment played in supporting struggling and advanced learners, I used practitioner research to examine the development and implementation of a differentiated, standards-based instructional unit around the conceptual topic of protein synthesis. I collected multiple data pieces for 10 students in the study: two advanced learners, four struggling learners, and four strong learners who struggled in biology. Data analyzed included formative, self-, and summative assessment results; student artifacts; informal and formal student interviews; and, a practitioner reflection journal chronicling critical incidents and actions taken during the development and implementation of this unit and notes from peer debriefing during and following the unit's implementation. As I analyzed the data collected, my four findings fell into two overarching categories related to student grouping. My first three findings reflect what I learned about homogeneous grouping: (1) Pre-assessment based on unit outcomes is not useful for determining groups for tiered instruction; (2) Decisions about differentiation and grouping for differentiation must be made in the act of teaching using formative assessment results; and, (3) Flexible grouping structures are effective for both struggling

  6. Die Transformation der NATO : amerikanische Vorstellungen und Risiken für Europa

    OpenAIRE

    Dembinski, Matthias

    2006-01-01

    'Die vom russischen Präsidenten Wladimir Putin im April 2007 verkündete Aussetzung des Vertrags über konventionelle Streitkräfte (KSE) wegen des geplanten US-Raketenschilds in Osteuropa ist nur die Spitze des Eisbergs der Verwerfungen zwischen der NATO und Russland. Der schon seit einigen Jahren andauernde Wandel der NATO, vor allem die Beitritte weiterer osteuropäischer Mitgliedsstaaten und die Ausweitung ihres Aufgaben- und Tätigkeitsbereichs, beunruhigen Moskau. Eine übermächtige, geeinte ...

  7. The Air War in Libya: Implications for the US, NATO, and the Future Role of Airpower

    Science.gov (United States)

    2012-04-23

    claiming it to be a model for future interventions.28 Still, others felt that OUP represented a “dark lesson for NATO,” exposing fissures in the...YES Mirage 2000D UNK YES YES YES YES Mirage F1CR UNK NO NO NO NO 39 Italy KC-130J YES NO YES YES YES Tornado ECR /IDS YES YES YES YES NO...htm (accessed on December 2, 2011). 2 Robert Marquand, “NATO operation in Libya ends after 7 months, could it be a model ?,” Christian Science

  8. The NATO-Russia Partnership: A Marriage of Convenience or a Troubled Relationship?

    Science.gov (United States)

    2006-11-01

    that, as Russia regenerates its autocratic imperial model of state building, it aspires to the goal of a free hand in creating an exclusive Eurasian...disputes with NATO countries (say because of certain territorial claims, or problems with oil production at sea, and fishing matters) into armed conflicts...to the Iraq invasion—with which NATO had nothing to do—it is “coming apart at the seams.”155 This ambivalence colors every aspect of this “ zebra

  9. The NATO Warsaw Summit: How to Strengthen Alliance Cohesion (Strategic Forum, Number 296)

    Science.gov (United States)

    2016-06-01

    solidarity among Europeans is under siege. NATO as an organization is not immune from these developments. On the one hand, both Russia and the Islamic ...BEL SVN CAN DEU HRV NOR FRA ESP HUN GBR USA TUR DNK NLD CZE ROU PRT EST GRC LVA SVK LUX POL LTU Figure. NATO Defense Expenditure Data Source: Defence...to Dr. G. Alexander Crowther, Daniel Fiott, Dr. Christopher J. Lamb, Colonel Rich- ard H.M. Outzen, USA , and Dr. Luis Simon for com- menting on an

  10. Use of animals by NATO countries in military medical training exercises: an international survey.

    Science.gov (United States)

    Gala, Shalin G; Goodman, Justin R; Murphy, Michael P; Balsam, Marion J

    2012-08-01

    Among the 28 member nations of the North Atlantic Treaty Organization (NATO), a variety of training methodologies--including simulators, moulage scenarios, didactics and live animal laboratories-are used to prepare military medical personnel to treat injured civilians and soldiers. For ethical, educational, practical, and economic reasons, the necessity of animal use for this purpose has come into question. This article reports the results of a survey examining the prevalence of animal use in military medical training exercises among all NATO nations, finding that more than three-quarters of these countries do not use animals.

  11. Challenges, Capability and Will: Is NATO Relevant in the Twenty-first Century

    Science.gov (United States)

    2015-05-23

    Distribution is Unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT Since the end of the Cold War NATO has struggled to maintain a raison d’être for its...Century? by LTC James K. Dunivan, U.S. Army, 55 pages. Since the end of the Cold War NATO has struggled to maintain a raison d’être for its continued...the past sixty-plus years. Perhaps speaking for many who welcome NATO’s commitment to trans-atlantic security, two statements by recent Allied

  12. Advanced treatment of biologically pretreated coal gasification wastewater by a novel integration of three-dimensional catalytic electro-Fenton and membrane bioreactor.

    Science.gov (United States)

    Jia, Shengyong; Han, Hongjun; Hou, Baolin; Zhuang, Haifeng

    2015-12-01

    Laboratorial scale experiments were conducted to investigate a novel system three-dimensional catalytic electro-Fenton (3DCEF, catalyst of sewage sludge based activated carbon which loaded Fe3O4) integrating with membrane bioreactor (3DCEF-MBR) on advanced treatment of biologically pretreated coal gasification wastewater. The results indicated that 3DCEF-MBR represented high efficiencies in eliminating COD and total organic carbon, giving the maximum removal efficiencies of 80% and 75%, respectively. The integrated 3DCEF-MBR system significantly reduced the transmembrane pressure, giving 35% lower than conventional MBR after 30 days operation. The enhanced hydroxyl radical oxidation and bacteria self repair function were the mechanisms for 3DCEF-MBR performance. Therefore, the integrated 3DCEF-MBR was expected to be the promising technology for advanced treatment in engineering applications.

  13. Biologic Treatments for Sports Injuries II Think Tank-Current Concepts, Future Research, and Barriers to Advancement, Part 2: Rotator Cuff.

    Science.gov (United States)

    Murray, Iain R; LaPrade, Robert F; Musahl, Volker; Geeslin, Andrew G; Zlotnicki, Jason P; Mann, Barton J; Petrigliano, Frank A

    2016-03-01

    Rotator cuff tears are common and result in considerable morbidity. Tears within the tendon substance or at its insertion into the humeral head represent a considerable clinical challenge because of the hostile local environment that precludes healing. Tears often progress without intervention, and current surgical treatments are inadequate. Although surgical implants, instrumentation, and techniques have improved, healing rates have not improved, and a high failure rate remains for large and massive rotator cuff tears. The use of biologic adjuvants that contribute to a regenerative microenvironment have great potential for improving healing rates and function after surgery. This article presents a review of current and emerging biologic approaches to augment rotator cuff tendon and muscle regeneration focusing on the scientific rationale, preclinical, and clinical evidence for efficacy, areas for future research, and current barriers to advancement and implementation.

  14. 烟草黑胫病生物防治研究进展%Research Advance in Biological Control of Tobacco Black Shank

    Institute of Scientific and Technical Information of China (English)

    周喜新; 周倩; 胡日生; 周冀衡

    2011-01-01

    This article reviews the research advance in the biological control of tobacco black shank from the following aspects; resistance -inducing chemicals, antagonistic fungus and phytogenic fungicide of tobacco black shank, and looks forward the control methods of tobacco black shank and their developmental prospects in the future.%从烟草黑胫病的诱抗剂、拮抗菌及植物源杀菌剂等方面综述了烟草黑胫病生物防治的研究进展,并展望了今后对烟草黑胫病的防治方法及其发展前景.

  15. 薄荷属植物分子生物学研究进展%Research Advance in Molecular Biology of Plants in Mentha Genus

    Institute of Scientific and Technical Information of China (English)

    王海棠; 于盱; 刘艳; 梁呈元; 李维林

    2012-01-01

    The author reviewed the research advance in the molecular biology of plants in Menthe genus, including enzymatic genes related to volatile oil synthesis way, limonene synthase gene, molecular evolution and so on.%从薄荷属植物挥发油合成途径相关酶基因、柠檬烯合酶基因和分子进化等方面对薄荷属植物的分子生物学研究进行了综述.

  16. Some Misconceptions in Meiosis Shown by Students Responding to an Advanced Level Practical Examination Question in Biology.

    Science.gov (United States)

    Brown, C. R.

    1990-01-01

    Discussed are problems revealed in student responses to a practical task which formed part of an advanced level examination. The frequencies with which some misconceptions about cell reproduction and genetics occurred are presented. The nature of these misconceptions is analyzed and their implications discussed. (CW)

  17. NATO and EU Need Not Enlarge Hand in Hand - Estonian President in Riga

    Index Scriptorium Estoniae

    2006-01-01

    Riias NATO tippkohtumise ajal toimunud rahvusvahelisel julgeolekukonverentsil esinenud president Toomas Hendrik Ilves toetas Euroopa Liidu edasist laienemist, kuid möönis ühenduses tekkinud nn. laienemisväsimust. Vabariigi President töövisiidil Läti Vabariiki ja Rootsi Kuningriiki 28.-30.11.2006

  18. Soviet Reactions to NATO’S Emerging Technologies for Deep Attack.

    Science.gov (United States)

    1985-08-01

    light conditions. * Automated command, control, communications and intelligence analysis systems capable of supporting rapid targeting. Supporting...Force Attack ( FOFA ) -- The concept enunciated by NATO Supreme Allied Commander, General Bernard Rogers. Also known as the "Rogers Plan," the concept

  19. Recasting NATO’s Strategic Concept. Possible Directions for the United States

    Science.gov (United States)

    2009-01-01

    PDF document was made available from www.rand.org as a public service of the RAND Corporation. Jump down to document THE ARTS CHILD POLICY CIVIL...D.C., GAO- 01-734, July 2001. As of September 1, 2009: http://purl.access.gpo.gov/GPO/LPS15511 Van Ham, Peter, “NATO and the Madonna Curve: Why a

  20. NATO (North Atlantic Treaty Organization) Politico-Military Consultation: Shaping Alliance Decisions,

    Science.gov (United States)

    1984-01-01

    to the relative size of the country involved. Former Secretary General Manlio Brosio has observed that for the larger allies, consultation is "a way...consultation. 21. Manlio Brosio, "Consultation and the Atlantic Alliance," Survival 16 (May-June 1974): 117. 22. Cleveland, NATO: The Transatlantic