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Sample records for biologist marvin goldman

  1. Human radiation studies: Remembering the early years: Oral history of radiation biologist Marvin Goldman, Ph.D., conducted December 22, 1994

    International Nuclear Information System (INIS)

    1995-09-01

    This report provides a transcript of an interview of Dr. Marvin Goldman by representatives of DOE's Office of Human Radiation Experiments. Dr. Goldman was chosen for this interview because of his work on bone-seeking radionuclides. After a brief biographical sketch Dr. Goldman related his experiences concerning his training and work at Rochester University, his work at Brookhaven National Laboratory, his participation in the Beagle Studies at University of California at Davis, his work with the Chernobyl Nuclear Plant Accident, his consultation work with Russian authorities on the health and ecological effects in their history, and finally his opinions and recommendations on human radiation research and the environmental cleanup of DOE sites

  2. Emma Goldman: Crusader for Children

    Science.gov (United States)

    Denman, Joy

    1977-01-01

    Author concentrates not on the fiery anarchism for which "Red" Emma Goldman was internationally famous, but on the dilemmas of an anarchist-educator as reflected in her attitude toward children. (Editor/RK)

  3. Emma Goldman: A Study in Female Agitation.

    Science.gov (United States)

    Berry, Elizabeth

    The role of the agitator in society and the special characteristics of women agitators--in particular, Emma Goldman, an American anarchist from the early twentieth century--are discussed in this paper. Specific examples of the rhetoric used by Emma Goldman in her speeches (supporting anarchism, against women's suffrage, against abortion control,…

  4. The Life and Work of Marvin Kenneth Simon

    KAUST Repository

    Alouini, Mohamed-Slim; Biglieri, Ezio; Divsalar, Dariush; Dolinar, Samuel; Goldsmith, Andrea J.; Milstein, Larry B.

    2016-01-01

    It is a measure of the importance and profundity of Marvin Kenneth Simon's contributions to communication theory that a tribute article and tutorial about his life and work is of current research relevance in spite of the continually accelerating

  5. Metode Perhitungan Angka Indeks Produktivitas Menggunakan Model Marvin E Mundel

    Directory of Open Access Journals (Sweden)

    Haryadi Sarjono

    2001-03-01

    Full Text Available There are several measures and methods to basically perform the productivity of calculation. Marvin E Mundel (1978 methods uses calculation approach  index number, which is amount that shows the difference change of time between basic period and actual period. The result can be decrease, stabil, or increase.

  6. MARVIN: Distributed reasoning over large-scale Semantic Web data

    NARCIS (Netherlands)

    Oren, E.; Kotoulas, S.; Anadiotis, G.; Siebes, R.M.; ten Teije, A.C.M.; van Harmelen, F.A.H.

    2009-01-01

    Many Semantic Web problems are difficult to solve through common divide-and-conquer strategies, since they are hard to partition. We present Marvin, a parallel and distributed platform for processing large amounts of RDF data, on a network of loosely coupled peers. We present our divide-conquer-swap

  7. Something to die for: Rebutting the Mirkin & Goldman dilemma

    DEFF Research Database (Denmark)

    Christiansen, Ask Vest

    2016-01-01

    This essay investigates the soundness of the oft-repeated result of the Mirkin / Goldman dilemma. It says that approximately fifty per cent of all athletes should be willing to die if Olympic gold was at stake. The essay analyses the premises for this “well-known-fact” and traces the source for t...

  8. A quantum Goldman bracket in (2 + 1) quantum gravity

    International Nuclear Information System (INIS)

    Nelson, J E; Picken, R F

    2008-01-01

    In the context of quantum gravity for spacetimes of dimension (2 + 1), we describe progress in the construction of a quantum Goldman bracket for intersecting loops on surfaces. Using piecewise linear paths in R 2 (representing loops on the spatial manifold, i.e. the torus) and a quantum connection with noncommuting components, we review how holonomies and Wilson loops for two homotopic paths are related by phases in terms of the signed area between them. Paths rerouted at intersection points with other paths occur on the rhs of the Goldman bracket. To better understand their nature we introduce the concept of integer points inside the parallelogram spanned by two intersecting paths, and show that the rerouted paths must necessarily pass through these integer points

  9. The Life and Work of Marvin Kenneth Simon

    KAUST Repository

    Alouini, Mohamed-Slim

    2016-12-30

    It is a measure of the importance and profundity of Marvin Kenneth Simon\\'s contributions to communication theory that a tribute article and tutorial about his life and work is of current research relevance in spite of the continually accelerating rate of evolution in this area. Marv, as the entire community affectionately knew him, was one of the most prolific and influential communications researchers of his generation. Moreover, he laid the foundation for many of the techniques used in communication systems today. Marv\\'s death on September 23, 2007 continues to engender pangs not only of sadness at the passing of a great friend to many in our community, but also of regret that he is no longer with us to help in resolving the many challenges facing communication systems today.

  10. "I am a trained nurse": the nursing identity of anarchist and radical Emma Goldman.

    Science.gov (United States)

    Connolly, Cynthia Anne

    2010-01-01

    For more than a century, scholars have analyzed the many dimensions of Emma Goldman. Remembered as an agent of revolution, feminism, sexual freedom, anarchy, and atheism, Goldman's motives, personality, and actions have generated an entire subgenre of historical scholarship. But although Goldman practiced nursing in New York City for ten years, one facet of her life that has been neglected is her nursing identity. Goldman's autobiography, Living My Life, reveals the way her nursing experiences informed her evolving anarchist political philosophy and international activism. She valued nursing for many reasons--for the economic independence it offered, identity it provided, and sense of community and connectivity she believed it encouraged. Finally, for Goldman, nursing represented was a vehicle to understand people's struggles and as a way of translating political philosophy into meaningful, practical solutions.

  11. Time and Architecture in Premodern Italy: A Review of Marvin Trachtenberg’s 'Building-In-Time'

    Directory of Open Access Journals (Sweden)

    Elizabeth Mays Merrill

    2013-08-01

    Full Text Available In this significant book, Marvin Trachtenberg constructs a new theory for understanding the structural and operational temporalities of building which gave rise to the monumental constructions of medieval and Renaissance Italy.

  12. A Biologist Looks at Cognitive Artificial Intelligence

    OpenAIRE

    Purves, William K.

    1985-01-01

    Although cognitive AI is not generally viewed as being "scientific" in the same, strong sense as is physics, it shares a number of the properties of the natural sciences, especially biology. Certain of special themes of biology, notably the principles of historicity and of structure-function relations, are applicable in AI research. From a biologist's viewpoint, certain principles of cognitive AI research emerge.

  13. 78 FR 24447 - Goldman Sachs Trust, et al.; Notice of Application

    Science.gov (United States)

    2013-04-25

    ... SECURITIES AND EXCHANGE COMMISSION [Investment Company Act Release No. 30471; 812-14075] Goldman Sachs Trust, et al.; Notice of Application April 19, 2013. AGENCY: Securities and Exchange Commission..., or cause more than 10% of the acquired company's voting stock to be owned by investment companies and...

  14. PURSUING AN EXCITING CAREER AS A WILDLIFE BIOLOGIST

    Science.gov (United States)

    Many people associate a career as a biologist to be similar to TV stars such as Jeff Corwin. Although biologists get to do exciting things like what viewers see on TV, being a biologist involves much more. I will talk about my career as a biologist, discuss experiences that you...

  15. Amando de olhos abertos: Emma Goldman e o dissenso político nos EUA Loving with open eyes: Emma Goldman and the political dissent in the Unites States

    Directory of Open Access Journals (Sweden)

    Cecilia Azevedo

    2007-12-01

    Full Text Available Este artigo apresenta a trajetória de Emma Goldman, grande nome do anarquismo, pacifismo e feminismo nos EUA, procurando apresentá- la como uma representante da chamada tradição de dissenso neste país que, ao longo de toda sua história, tem disputado os sentidos a serem atribuídos aos ideais nacionais. Em meio à atual guerra no Iraque, a memória e o legado de Emma Goldman vêm sendo recuperados no embate político em torno do sentido do americanismo.This article presents the life of Emma Goldman, who played a central role in the history of anarchism, pacifism and feminism in the United States. In the present days, when a new war is taking place in Iraq, the memory and legacy of Emma Goldman are being reassessed amidst the debate over the political meaning of Americanism.

  16. Entrevista con Marcio Goldman, Museo Nacional de la Universidad Federal de Río de Janeiro

    Directory of Open Access Journals (Sweden)

    Giovanna Bacchiddu

    2015-09-01

    Full Text Available Marcio Goldman, doctor en Antropología por la Universidad Federal de Río de Janeiro y actualmente profesor del Museo Nacional de la UFRJ, se ha dedicado al estudio antropológico de las religiones afrobrasileñas y de la política. Ha sido profesor visitante en distintas universidades como la Universidad de São Paulo (USP, Universidad de Cabo Verde y Universidad de Chicago. Entre los libros publicados por Marcio Goldman encontramos Razão e Diferença. Afetividade, Racionalidade e Relativismo no Pensamento de Lévy-Bruhl (1994, Alguma Antropologia (1999 y Como Funciona a Democracia. Uma Teoria Etnográfica da Política (2006 —traducido al inglés como How Democracy Works. An Ethnographic Theory of Politics, 2013—. Su trabajo ha sido publicado en numerosas revistas como Social Analysis, Mana y Ethnos. Actualmente, Marcio Goldman lleva a cabo una investigación acerca de las cosmopolíticas de las religiones de matriz africana en Brasil a partir de un trabajo de campo realizado en un terreiro (templo de Candomblé en la ciudad de Ilhéus, en el sur del Estado de Bahía, el que resultará prontamente en un libro. Esta entrevista fue realizada en el marco de una visita al Departamento de Antropología de la Pontificia Universidad Católica de Chile.

  17. Which statistics should tropical biologists learn?

    Science.gov (United States)

    Loaiza Velásquez, Natalia; González Lutz, María Isabel; Monge-Nájera, Julián

    2011-09-01

    Tropical biologists study the richest and most endangered biodiversity in the planet, and in these times of climate change and mega-extinctions, the need for efficient, good quality research is more pressing than in the past. However, the statistical component in research published by tropical authors sometimes suffers from poor quality in data collection; mediocre or bad experimental design and a rigid and outdated view of data analysis. To suggest improvements in their statistical education, we listed all the statistical tests and other quantitative analyses used in two leading tropical journals, the Revista de Biología Tropical and Biotropica, during a year. The 12 most frequent tests in the articles were: Analysis of Variance (ANOVA), Chi-Square Test, Student's T Test, Linear Regression, Pearson's Correlation Coefficient, Mann-Whitney U Test, Kruskal-Wallis Test, Shannon's Diversity Index, Tukey's Test, Cluster Analysis, Spearman's Rank Correlation Test and Principal Component Analysis. We conclude that statistical education for tropical biologists must abandon the old syllabus based on the mathematical side of statistics and concentrate on the correct selection of these and other procedures and tests, on their biological interpretation and on the use of reliable and friendly freeware. We think that their time will be better spent understanding and protecting tropical ecosystems than trying to learn the mathematical foundations of statistics: in most cases, a well designed one-semester course should be enough for their basic requirements.

  18. Mars Atmosphere Resource Verification INsitu (MARVIN) - In Situ Resource Demonstration for the Mars 2020 Mission

    Science.gov (United States)

    Sanders, Gerald B.; Araghi, Koorosh; Ess, Kim M.; Valencia, Lisa M.; Muscatello, Anthony C.; Calle, Carlos I.; Clark, Larry; Iacomini, Christie

    2014-01-01

    The making of oxygen from resources in the Martian atmosphere, known as In Situ Resource Utilization (ISRU), has the potential to provide substantial benefits for future robotic and human exploration. In particular, the ability to produce oxygen on Mars for use in propulsion, life support, and power systems can provide significant mission benefits such as a reducing launch mass, lander size, and mission and crew risk. To advance ISRU for possible incorporation into future human missions to Mars, NASA proposed including an ISRU instrument on the Mars 2020 rover mission, through an announcement of opportunity (AO). The purpose of the the Mars Atmosphere Resource Verification INsitu or (MARVIN) instrument is to provide the first demonstration on Mars of oxygen production from acquired and stored Martian atmospheric carbon dioxide, as well as take measurements of atmospheric pressure and temperature, and of suspended dust particle sizes and amounts entrained in collected atmosphere gases at different times of the Mars day and year. The hardware performance and environmental data obtained will be critical for future ISRU systems that will reduce the mass of propellants and other consumables launched from Earth for robotic and human exploration, for better understanding of Mars dust and mitigation techniques to improve crew safety, and to help further define Mars global circulation models and better understand the regional atmospheric dynamics on Mars. The technologies selected for MARVIN are also scalable for future robotic sample return and human missions to Mars using ISRU.

  19. Trading Health Risks for Glory: A Reformulation of the Goldman Dilemma.

    Science.gov (United States)

    González, Juan Marcos; Johnson, F Reed; Fedoruk, Matthew; Posner, Joshua; Bowers, Larry

    2018-03-01

    The Goldman dilemma presented athletes with a Faustian bargain that guaranteed winning an Olympic gold medal in their sport but resulted in certain death 5 years later. Athletes' responses to Goldman's bargain were reported from 1982 to 1995. Several studies subsequently evaluated people's willingness to accept the bargain proposed in the Goldman question. Our study updates Goldman's question using contingent-behavior questions, a preference-elicitation method widely applied in economics, marketing and psychology to understand people's choice behavior. Contingent-behavior questions ask people to evaluate hypothetical tradeoffs between outcomes when real-world decisions are unobservable, nonexistent, or unreliable. A web-enabled survey was conducted with athletes in 50 sports between June, 2012 and April, 2013. Athletes were invited by their sport governing bodies in the United States to complete the online survey. Responses from 2888 athletes were collected. Our reformulation elicited athletes' willingness to accept a performance-enhancing drug (PED) associated with the risk of a realistic fatal event, not certain death. A double-bounded dichotomous-choice question format was used to elicit athletes' maximum acceptable mortality risk (MAMR) for winning an Olympic gold medal. Data were analyzed using an interval regression model to estimate the implicit probability of accepting a continuous risk level. MAMR was defined as the mortality risk level with a 0.50 probability of acceptance. Estimated mean MAMRs varied between 7 and 14% across athletes in different ranks and sports. Elite athletes were generally the most willing to accept a fatal cardiovascular risk to win a gold medal in the Olympics. This range was similar to the levels of risk that patients accept for life-changing interventions. Results suggest that very few athletes would be expected to accept a PED in the bargain postulated by the Goldman dilemma. Risk tolerance among elite athletes suggest they may

  20. Marvin: an anatomical phantom for dosimetric evaluation of complex radiotherapy of the head and neck

    Science.gov (United States)

    Aitkenhead, A. H.; Rowbottom, C. G.; Mackay, R. I.

    2013-10-01

    We report on the design of Marvin, a Model Anatomy for Radiotherapy Verification and audit In the head and Neck and present results demonstrating its use in the development of the Elekta volumetric modulated arc therapy (VMAT) technique at the Christie, and in the audit of TomoTherapy and Varian RapidArc at other institutions. The geometry of Marvin was generated from CT datasets of eight male and female patients lying in the treatment position, with removable inhomogeneities modelling the sinuses and mandible. A modular system allows the phantom to be used with a range of detectors, with the locations of the modules being based on an analysis of a range of typical treatment plans (27 in total) which were mapped onto the phantom geometry. Results demonstrate the use of Gafchromic EBT2/EBT3 film for measurement of relative dose in a plane through the target and organs-at-risk, and the use of a small-volume ionization chamber for measurement of absolute dose in the target and spinal cord. Measurements made during the development of the head and neck VMAT protocol at the Christie quantified the improvement in plan delivery resulting from the installation of the Elekta Integrity upgrade (which permits an effectively continuously variable dose rate), with plans delivered before and after the upgrade having 88.5 ± 9.4% and 98.0 ± 2.2% respectively of points passing a gamma analysis (at 4%, 4 mm, global). Audits of TomoTherapy and Varian RapidArc neck techniques at other institutions showed a similar quality of plan delivery as for post-Integrity Elekta VMAT: film measurements for both techniques had >99% of points passing a gamma analysis at the clinical criteria of 4%, 4 mm, global, and >95% of points passing at tighter criteria of 3%, 3 mm, global; and absolute dose measurements in the PTV and spinal cord were within 1.5% and 3.5% of the planned doses respectively for both techniques. The results demonstrate that Marvin is an efficient and effective means of

  1. Marvin: an anatomical phantom for dosimetric evaluation of complex radiotherapy of the head and neck

    International Nuclear Information System (INIS)

    Aitkenhead, A H; Rowbottom, C G; Mackay, R I

    2013-01-01

    We report on the design of Marvin, a Model Anatomy for Radiotherapy Verification and audit In the head and Neck and present results demonstrating its use in the development of the Elekta volumetric modulated arc therapy (VMAT) technique at the Christie, and in the audit of TomoTherapy and Varian RapidArc at other institutions. The geometry of Marvin was generated from CT datasets of eight male and female patients lying in the treatment position, with removable inhomogeneities modelling the sinuses and mandible. A modular system allows the phantom to be used with a range of detectors, with the locations of the modules being based on an analysis of a range of typical treatment plans (27 in total) which were mapped onto the phantom geometry. Results demonstrate the use of Gafchromic EBT2/EBT3 film for measurement of relative dose in a plane through the target and organs-at-risk, and the use of a small-volume ionization chamber for measurement of absolute dose in the target and spinal cord. Measurements made during the development of the head and neck VMAT protocol at the Christie quantified the improvement in plan delivery resulting from the installation of the Elekta Integrity upgrade (which permits an effectively continuously variable dose rate), with plans delivered before and after the upgrade having 88.5 ± 9.4% and 98.0 ± 2.2% respectively of points passing a gamma analysis (at 4%, 4 mm, global). Audits of TomoTherapy and Varian RapidArc neck techniques at other institutions showed a similar quality of plan delivery as for post-Integrity Elekta VMAT: film measurements for both techniques had >99% of points passing a gamma analysis at the clinical criteria of 4%, 4 mm, global, and >95% of points passing at tighter criteria of 3%, 3 mm, global; and absolute dose measurements in the PTV and spinal cord were within 1.5% and 3.5% of the planned doses respectively for both techniques. The results demonstrate that Marvin is an efficient and effective means of

  2. Which statistics should tropical biologists learn?

    Directory of Open Access Journals (Sweden)

    Natalia Loaiza Velásquez

    2011-09-01

    Full Text Available Tropical biologists study the richest and most endangered biodiversity in the planet, and in these times of climate change and mega-extinctions, the need for efficient, good quality research is more pressing than in the past. However, the statistical component in research published by tropical authors sometimes suffers from poor quality in data collection; mediocre or bad experimental design and a rigid and outdated view of data analysis. To suggest improvements in their statistical education, we listed all the statistical tests and other quantitative analyses used in two leading tropical journals, the Revista de Biología Tropical and Biotropica, during a year. The 12 most frequent tests in the articles were: Analysis of Variance (ANOVA, Chi-Square Test, Student’s T Test, Linear Regression, Pearson’s Correlation Coefficient, Mann-Whitney U Test, Kruskal-Wallis Test, Shannon’s Diversity Index, Tukey’s Test, Cluster Analysis, Spearman’s Rank Correlation Test and Principal Component Analysis. We conclude that statistical education for tropical biologists must abandon the old syllabus based on the mathematical side of statistics and concentrate on the correct selection of these and other procedures and tests, on their biological interpretation and on the use of reliable and friendly freeware. We think that their time will be better spent understanding and protecting tropical ecosystems than trying to learn the mathematical foundations of statistics: in most cases, a well designed one-semester course should be enough for their basic requirements. Rev. Biol. Trop. 59 (3: 983-992. Epub 2011 September 01.Los biólogos tropicales estudian la biodiversidad más rica y amenazada del planeta, y en estos tiempos de cambio climático y mega-extinción, la necesidad de investigación de buena calidad es más acuciante que en el pasado. Sin embargo, el componente estadístico en la investigación publicada por los autores tropicales adolece a veces

  3. The Effect of Various Contact Lenses on Intraocular Pressure Measurement by Goldman Tonometer

    Directory of Open Access Journals (Sweden)

    Monireh Mahjoob

    2014-06-01

    Full Text Available Background: Today, contact lenses have extensive usages. Contact lens places on cornea, so it may induce variation on cornea and these variations can influence the measurement of intraocular pressure (IOP by Goldman tonometer. The aim of this research was to study the effect of various contact lenses on measurement of intraocular pressure by Goldman tonometer. Materials and Methods: In this study, 80 subjects aged 18-25 were selected randomly among patients of Al-Zahra ophthalmology center. None of them has any eye pathological problems. Before wearing the lens, intraocular pressure was measured, and then patients were divided into two groups of soft and hard contact lenses. Soft and hard contact lenses were placed on the eye for two hours, and the intraocular pressure was measured again. Results: The mean of IOP before wearing contact lenses and two hours later was 15.96 mmHg and 13.93, s respectively. Paired test showed a significant difference between IOP before and after wearing contact lenses (p=0.001.There was no significant differences in mean of intraocular pressure decline before and after placing the contact lens in both soft and hard lenses. Conclusion: According to this study, the intraocular pressure decreases after wearing contact lenses (CL. This decline may be due to variation in properties of cornea after wearing CL that can also affect IOP measurement.

  4. Meet EPA Biologist Thomas Knudsen, Ph.D.

    Science.gov (United States)

    Dr. Tom Knudsen is a developmental systems biologist at EPA's Center for Computational Toxicology. His research focuses on the potential for chemicals to disrupt prenatal development—one of the most important life stages.

  5. Dynamic contour tonometry and goldman applanation tonometry in eyes with keratoconus Tonometria de contorno dinâmico e tonometria de aplanação de goldman em olhos com ceratocone

    OpenAIRE

    Jackson Barreto Jr; Mirko Babic; Roberto Murad Vessani; Remo Susanna Jr.

    2006-01-01

    PURPOSE: The dynamic contour tonometer is a nonapplanation contact tonometer designed to be largely independent of the structural properties of the cornea. Theoretically, it may measure intraocular pressure most accurately in abnormally thinner corneas. This study compares intraocular pressure measurements by dynamic contour tonometry with Goldman applanation tonometry in eyes with normal corneas and eyes with advanced keratoconus. METHODS: A comparative case series. Subjects underwent intrao...

  6. The Society of Brains: How Alan Turing and Marvin Minsky Were Both Right

    Science.gov (United States)

    Struzik, Zbigniew R.

    2015-04-01

    In his well-known prediction, Alan Turing stated that computer intelligence would surpass human intelligence by the year 2000. Although the Turing Test, as it became known, was devised to be played by one human against one computer, this is not a fair setup. Every human is a part of a social network, and a fairer comparison would be a contest between one human at the console and a network of computers behind the console. Around the year 2000, the number of web pages on the WWW overtook the number of neurons in the human brain. But these websites would be of little use without the ability to search for knowledge. By the year 2000 Google Inc. had become the search engine of choice, and the WWW became an intelligent entity. This was not without good reason. The basis for the search engine was the analysis of the ’network of knowledge’. The PageRank algorithm, linking information on the web according to the hierarchy of ‘link popularity’, continues to provide the basis for all of Google's web search tools. While PageRank was developed by Larry Page and Sergey Brin in 1996 as part of a research project about a new kind of search engine, PageRank is in its essence the key to representing and using static knowledge in an emergent intelligent system. Here I argue that Alan Turing was right, as hybrid human-computer internet machines have already surpassed our individual intelligence - this was done around the year 2000 by the Internet - the socially-minded, human-computer hybrid Homo computabilis-socialis. Ironically, the Internet's intelligence also emerged to a large extent from ‘exploiting’ humans - the key to the emergence of machine intelligence has been discussed by Marvin Minsky in his work on the foundations of intelligence through interacting agents’ knowledge. As a consequence, a decade and a half decade into the 21st century, we appear to be much better equipped to tackle the problem of the social origins of humanity - in particular thanks to the

  7. "Marvin, the Paranoid Android": The Case of an Alpha-PVP User in the Expanding Galaxy of NPS.

    Science.gov (United States)

    Pierluigi, Simonato; Laura, Bulsis; Attilio, Negri; Gurjeet K, Bansal; Gloria, Pessa; Davide, Mioni; Borgherini, Giuseppe; Giovanni, Martinotti; Fabrizio, Schifano; Perini, Giulia; Ornella, Corazza

    2018-05-16

    Alpha-PVP can be defined as a novel psychoactive substance (NPS)-more specifically, a novel synthetic cathinone with unpredictable stimulant effects in humans. "Marvin" arrived at a Dual Diagnosis Unit at Parco dei Tigli, Italy. He underwent a 30-day rehabilitation program to overcome his problematic Alpha-PVP use as a psychonaut. We conducted an online search to understand the properties of Alpha-PVP and its presence in scientific literature, reviewing official reports and the online drug market (e.g., fora, webpages). In the Dual Diagnosis Unit, Marvin completed the 30-day rehabilitation program that included assessments and group and individual cognitive behavioral therapy. Alpha-PVP is a synthetic cathinone with stimulant properties, available in the online market but with unpredictable effects in humans. The present case reports an important risk of psychosis in a psychonaut patient who arrived and declared its intense use before admission to our Unit. This article describes the psychopathological effects of the novel compound Alpha-PVP in a psychonaut patient. Patients attending clinics that have used Alpha-PVP pose a new challenge for traditional services of mental health and addiction.

  8. the contrasting attitudes of plant breeders and molecular biologists ...

    Indian Academy of Sciences (India)

    Socialization into disciplinary cultures, organizational factors and individual anxieties seem to inhibit inter-disciplinary collaboration. The majority of rice breeders and a small group of molecular biologists emphasize the relative merits of marker-assisted selection (MAS) in the near term vis-à-vis the currently controversial ...

  9. Dr Jacob van der Land, marine biologist extraordinary

    NARCIS (Netherlands)

    Bruggen, van A.C.

    2001-01-01

    This contribution is an attempt to sketch the life and works of Dr Jacob van der Land, curator of worms and chief marine biologist of the National Museum of Natural History, on the occasion of his official retirement. Born in 1935, Jacob van der Land read biology at Leiden University (1958-1964),

  10. THE DESCENT OF LANGUAGE. A CONVERSATION BETWEEN TWO JOBLESS BIOLOGISTS

    Directory of Open Access Journals (Sweden)

    D'Angelo Giovanni

    2013-12-01

    Full Text Available Seen from the perspective of a biologist, the issue of the origin of language contains an inherent ambiguity. On the one hand, one might think to explore the cognitive features or even the anatomical structures related to communication through the peculiar medium called verbal language, a characteristic property emergent among the Homo sapiens. On the other hand, if one decides to restrict oneself to the formal definition of language as a system of signs for encoding information, then, the human-specific nature of language becomes less convincing and the temptation to look into non-human languages allows a provocative question. Was human verbal language an invention or a discovery? In the following two biologists informally discuss about the concept of non-verbal biological languages.

  11. Dr Jacob van der Land, marine biologist extraordinary

    OpenAIRE

    Bruggen, van, A.C.

    2001-01-01

    This contribution is an attempt to sketch the life and works of Dr Jacob van der Land, curator of worms and chief marine biologist of the National Museum of Natural History, on the occasion of his official retirement. Born in 1935, Jacob van der Land read biology at Leiden University (1958-1964), where he obtained his Ph.D. in 1970 on a treatise on the Priapulida under the supervision of Prof. Dr L.D. Brongersma. In 1964 he was appointed curator of worms in the museum. Later on he took over l...

  12. Improving interactions between animal rights groups and conservation biologists.

    Science.gov (United States)

    Perry, Dan; Perry, Gad

    2008-02-01

    Invasive species are often considered to be a major threat to biodiversity, leading conservation biologists to often recommend their complete eradication. Animal rights groups typically categorically oppose killing animals, and their opposition has brought eradication attempts of gray squirrels in northern Italy (Europe) and mute swans in Vermont to a halt. As a result native red squirrels may disappear from Europe and ecosystem-wide impacts are expected to be caused by the swan. In contrast, cooperation between managers and animal rights groups has resulted in a successful control program for feral pigs in Fort Worth, Texas (U.S.A.). The philosophical differences between animal rights and conservation biologists' views make cooperation seem unlikely, yet documented cases of cooperation have been beneficial for both groups. We recommend that managers dealing with invasive species should consult with social scientists and ethicists to gain a better understanding of the implications of some of their policy decisions. In addition, we recommend that animal rights groups do more to support alternatives to lethal control, which are often excluded by economic limitations. Prevention of arrival of invasive species via application of the precautionary principle may be an especially productive avenue for such collaboration because it fits the goals and values of both groups.

  13. Dynamic contour tonometry and goldman applanation tonometry in eyes with keratoconus Tonometria de contorno dinâmico e tonometria de aplanação de goldman em olhos com ceratocone

    Directory of Open Access Journals (Sweden)

    Jackson Barreto Jr

    2006-01-01

    Full Text Available PURPOSE: The dynamic contour tonometer is a nonapplanation contact tonometer designed to be largely independent of the structural properties of the cornea. Theoretically, it may measure intraocular pressure most accurately in abnormally thinner corneas. This study compares intraocular pressure measurements by dynamic contour tonometry with Goldman applanation tonometry in eyes with normal corneas and eyes with advanced keratoconus. METHODS: A comparative case series. Subjects underwent intraocular pressure measurements by dynamic contour tonometry, Goldman applanation tonometry, ultrasonic pachymetry, and slit scanning topography. Exclusion criteria: any ocular pathology other than keratoconus, previous corneal or refractive surgery, stromal scarring due to acute hydrops, or any other corneal opacities. RESULTS: Ten patients with keratoconus were included in Group A, and 12 normal patients composed Group B according to the pre-established criteria. The mean Goldman tonometry measurement in group A was 10.3 ± 1.8 mm Hg and group B was 14.3 ± 0.75 mm Hg. (P = 0.024. In group A, the mean measurement with the dynamic contour tonometer was 14.6 ± 2.09 mm Hg, and in group B, it was 17.4 ± 3.1 mm Hg (P = 0.026. The difference between both methods of measurement in group A was statistically significant (P OBJETIVO: O tonômetro de contorno dinâmico é um aparelho de contato e não-aplanação projetado para ser independente das propriedades estruturais da córnea. Teoricamente, ele mede de forma mais precisa a pressão intra-ocular em córneas muito finas. Este estudo compara as medidas de pressão intra-ocular pelo tonômetro de contorno dinâmico com a tonometria de aplanação de Goldman em olhos normais e em olhos com ceratocone avançado. MÉTODOS: uma série comparativa de casos. Pacientes foram submetidos às medidas de pressão intra-ocular por ambos os métodos mencionados, paquimetria ultrassônica e topografia corneana de varredura. Crit

  14. Biological and communication skills needed for introduced fish biologists

    Science.gov (United States)

    Bonar, Scott A.

    2016-01-01

    What skills and knowledge will a new graduate seeking employment need to work with introduced fishes? Clearly, success in introduced species management—similar to other disciplines in fisheries—requires a mixture of scientific and communication skills. However, specific abilities especially important to a biologist who manages introduced fishes should be highlighted. Unlike most other management strategies, stocking an introduced species can result in unintended and irreversible impacts, so particular care must be employed when stocking is considered. Furthermore, fish populations in areas outside of the introduced species management area might also be affected, usually negatively, if the introduced fish escapes. Therefore, rock-solid knowledge of basic aquatic ecology, including risk management; fish taxonomy (so the wrong fish species is not mistakenly stocked!); familiarity with human values of both the time and the place (which requires communication skills); and a strong understanding of human history are all important.

  15. Engineers are from PDMS-land, Biologists are from Polystyrenia.

    Science.gov (United States)

    Berthier, Erwin; Young, Edmond W K; Beebe, David

    2012-04-07

    As the integration of microfluidics into cell biology research proceeds at an ever-increasing pace, a critical question for those working at the interface of both disciplines is which device material to use for a given application. While PDMS and soft lithography methods offer the engineer rapid prototyping capabilities, PDMS as a material has characteristics that have known adverse effects on cell-based experiments. In contrast, while polystyrene (PS), the most commonly used thermoplastic for laboratory cultureware, has provided decades of grounded and validated research conclusions in cell behavior and function, PS as a material has posed significant challenges in microfabrication. These competing issues have forced microfluidics engineers and biologists to make compromises in how they approach specific research questions, and furthermore, have attenuated the impact of microfluidics on biological research. In this review, we provide a comparison of the attributes of PDMS and PS, and discuss reasons for their popularity in their respective fields. We provide a critical evaluation of the strengths and limitations of PDMS and PS in relation to the advancement and future impact on microfluidic cell-based studies and applications. We believe that engineers have a responsibility to overcome any challenges associated with microfabrication, whether with PS or other materials, and that engineers should provide options and solutions that assist biologists in their experimental design. Our goal is not to advocate for any specific material, but provide guidelines for researchers who desire to choose the most suitable material for their application, and suggest important research directions for engineers working at the interface between microfabrication technology and biological application. This journal is © The Royal Society of Chemistry 2012

  16. Applying Item Response Theory to the Development of a Screening Adaptation of the Goldman-Fristoe Test of Articulation-Second Edition

    Science.gov (United States)

    Brackenbury, Tim; Zickar, Michael J.; Munson, Benjamin; Storkel, Holly L.

    2017-01-01

    Purpose: Item response theory (IRT) is a psychometric approach to measurement that uses latent trait abilities (e.g., speech sound production skills) to model performance on individual items that vary by difficulty and discrimination. An IRT analysis was applied to preschoolers' productions of the words on the Goldman-Fristoe Test of…

  17. Charles William Lacaillade. Biologist, Parasitologist, Educator, and Mentor.

    Science.gov (United States)

    Imperato, Pascal James

    2017-02-01

    Charles William Lacaillade (1904-1978) was an eminent biologist in the middle decades of the twentieth century. He was born in Lawrence, Massachusetts of parents whose ancestors were French Canadians. His father, also named Charles William Lacaillade, was a dentist who graduated from Tufts University School of Dentistry in 1898. His mother, Elodia Eno, came from a family of very successful businessmen. Lacaillade was the third of six children. His two older brothers, Harold Carleton and Hector Eno, both graduated from the University of Louisville, School of Dentistry, while his younger brother, Lawrence, became a businessman. His sister, Luemma, married Dr. Henry Steadman, a veterinarian, while his youngest sister, Gloria, married a U.S. Army officer, Lieutenant Colonel Victor Anido. Lacaillade received his MS and PhD degrees in biology and zoology from Harvard University. He then became a fellow at The Rockefeller Institute for Medical Research. At both institutions, he studied under some of the most eminent biological scientists of the time. These included Rudolf W. Glaser, George Howard Parker, Theobald Smith, Carl TenBroeck, and William Morton Wheeler. At the Rockefeller Institute, he co-discovered the vector and mode of transmission of Eastern Equine Encephalomyelitis. This discovery, and the research he conducted with Rudolf W. Glaser, quickly established him as an outstanding biological researcher. However, a change in leadership at the Rockefeller Institute resulted in research priorities being given to the disciplines of general physiology, physical chemistry, and nutrition. This shift in the research agenda away from the biological sciences precluded career advancement at the Rockefeller Institute for post-doctoral fellows like Lacaillade. It was the height of the Great Depression, and even biologists with terminal doctoral degrees found it difficult to find positions. In 1935, Lacaillade accepted a position as an assistant in biology at St. John

  18. Eukaryotic systematics: a user's guide for cell biologists and parasitologists.

    Science.gov (United States)

    Walker, Giselle; Dorrell, Richard G; Schlacht, Alexander; Dacks, Joel B

    2011-11-01

    Single-celled parasites like Entamoeba, Trypanosoma, Phytophthora and Plasmodium wreak untold havoc on human habitat and health. Understanding the position of the various protistan pathogens in the larger context of eukaryotic diversity informs our study of how these parasites operate on a cellular level, as well as how they have evolved. Here, we review the literature that has brought our understanding of eukaryotic relationships from an idea of parasites as primitive cells to a crystallized view of diversity that encompasses 6 major divisions, or supergroups, of eukaryotes. We provide an updated taxonomic scheme (for 2011), based on extensive genomic, ultrastructural and phylogenetic evidence, with three differing levels of taxonomic detail for ease of referencing and accessibility (see supplementary material at Cambridge Journals On-line). Two of the most pressing issues in cellular evolution, the root of the eukaryotic tree and the evolution of photosynthesis in complex algae, are also discussed along with ideas about what the new generation of genome sequencing technologies may contribute to the field of eukaryotic systematics. We hope that, armed with this user's guide, cell biologists and parasitologists will be encouraged about taking an increasingly evolutionary point of view in the battle against parasites representing real dangers to our livelihoods and lives.

  19. Results of the radiological verification survey at the former Herring-Hall-Marvin Safe Company, 1550 Grand Boulevard, Hamilton Ohio (HO001V)

    International Nuclear Information System (INIS)

    Murray, M.E.; allred, J.F.; Johnson, C.A.

    1995-11-01

    During the period between the 1940s and early 1950s, the Herring-Hall-Marvin Safe Company, 1550 Grand Boulevard, Hamilton, Ohio, was one company under subcontract to the Manhattan Engineer District (MED), and the Atomic Energy Commission (AEC), the lead agencies in the development of nuclear energy for defense-related projects. The US Department of Energy (DOE) conducted radiological surveys of these sites to evaluate current radiological conditions as part of the Formerly Utilized Sites Remedial Action Program (FUSRAP). In 1988, a radiological survey of the Herring-Hall-Marvin Safe Company facility was conducted, and after small fragments of uranium metal were removed, no beta or gamma radiation above background was detected and the building was dismissed from any additional DOE restrictions. In 1993, it was discovered that a portion of the actual machining work was conducted on the third floor of the facility, located in the southeastern comer of the building. At the request of DOE, this part of the facility was radiologically surveyed by an ORNL survey team to determine whether fixed surface contamination could be found that might exceed the DOE guidelines. Results of this radiological survey indicated 238 U contamination in excess of the DOE criteria for surface contamination, and the site was recommended for remediation. In February and March of 1995, a verification survey of the third floor of the former Herring-Hall-Marvin Safe Company facility by an ORNL survey team was performed in conjunction with decontamination operations conducted under the supervision of Bechtel National Incorporated. The verification survey included gamma scans at the surface and at one meter, alpha and beta-gamma scans for fixed contamination, and smears for transferable contamination

  20. Determining k channel activation curves from k channel currents often requires the goldman-hodgkin-katz equation.

    Science.gov (United States)

    Clay, John R

    2009-01-01

    Potassium ion current in nerve membrane, I(K), has traditionally been described by I(K) = g(K)(V - E(K)), where g(K) is the K ion conductance, V is membrane potential and E(K) is the K(+) Nernst potential. This description has been unchallenged by most investigators in neuroscience since its introduction almost 60 years ago. The problem with the I(K) approximately (V - E(K)) proportionality is that it is inconsistent with the unequal distribution of K ions in the intra- and extracellular bathing media. Under physiological conditions the intracellular K(+) concentration is significantly higher than the extracellular concentration. Consequently, the slope conductance at potentials positive to E(K) cannot be the same as that for potentials negative to E(K), as the linear proportionality between I(K) and (V - E(K)) requires. Instead I(K) has a non-linear dependence on (V - E(K)) which is well described by the Goldman-Hodgkin-Katz equation. The implications of this result for K(+) channel gating and membrane excitability are reviewed in this report.

  1. Determining K+ channel activation curves from K+ channel currents often requires the Goldman-Hodgkin-Katz equation

    Directory of Open Access Journals (Sweden)

    john r Clay

    2009-12-01

    Full Text Available Potassium ion current in nerve membrane, IK, has traditionally been described by IK = gK(V-EK, where gK is the K ion conductance, V is membrane potential, and EK is the K+ Nernst potential. This description has been unchallenged by most investigators in neuroscience since its introduction almost sixty years ago. The problem with the IK ~ (V-EK proportionality is that it is inconsistent with the unequal distribution of K ions in the intra- and extracellular bathing media. Under physiological conditions the intracellular K+ concentraion is significantly higher than the extracellular concentration. Consequently, the slope conductance at potentials positive to EK cannot be the same as that for potentials negative to EK, as the linear proportionality requires. Instead IK has a non-linear dependence on (V-EK which is well described by the Goldman-Hodgkin-Katz equation. The implications of this result for K+ channel gating and membrane excitability are reviewed in this report.

  2. Generation of membrane potential beyond the conceptual range of Donnan theory and Goldman-Hodgkin-Katz equation.

    Science.gov (United States)

    Tamagawa, Hirohisa; Ikeda, Kota

    2017-09-01

    Donnan theory and Goldman-Hodgkin-Katz equation (GHK eq.) state that the nonzero membrane potential is generated by the asymmetric ion distribution between two solutions separated by a semipermeable membrane and/or by the continuous ion transport across the semipermeable membrane. However, there have been a number of reports of the membrane potential generation behaviors in conflict with those theories. The authors of this paper performed the experimental and theoretical investigation of membrane potential and found that (1) Donnan theory is valid only when the macroscopic electroneutrality is sufficed and (2) Potential behavior across a certain type of membrane appears to be inexplicable on the concept of GHK eq. Consequently, the authors derived a conclusion that the existing theories have some limitations for predicting the membrane potential behavior and we need to find a theory to overcome those limitations. The authors suggest that the ion adsorption theory named Ling's adsorption theory, which attributes the membrane potential generation to the mobile ion adsorption onto the adsorption sites, could overcome those problems.

  3. What Neural Substrates Trigger the Adept Scientific Pattern Discovery by Biologists?

    Science.gov (United States)

    Lee, Jun-Ki; Kwon, Yong-Ju

    2011-04-01

    This study investigated the neural correlates of experts and novices during biological object pattern detection using an fMRI approach in order to reveal the neural correlates of a biologist's superior pattern discovery ability. Sixteen healthy male participants (8 biologists and 8 non-biologists) volunteered for the study. Participants were shown fifteen series of organism pictures and asked to detect patterns amid stimulus pictures. Primary findings showed significant activations in the right middle temporal gyrus and inferior parietal lobule amongst participants in the biologist (expert) group. Interestingly, the left superior temporal gyrus was activated in participants from the non-biologist (novice) group. These results suggested that superior pattern discovery ability could be related to a functional facilitation of the parieto-temporal network, which is particularly driven by the right middle temporal gyrus and inferior parietal lobule in addition to the recruitment of additional brain regions. Furthermore, the functional facilitation of the network might actually pertain to high coherent processing skills and visual working memory capacity. Hence, study results suggested that adept scientific thinking ability can be detected by neuronal substrates, which may be used as criteria for developing and evaluating a brain-based science curriculum and test instrument.

  4. What cell biologists should know about the National Institutes of Health BRAIN Initiative

    OpenAIRE

    Insel, Thomas R.; Koroshetz, Walter

    2015-01-01

    The BRAIN (Brain Research through Advancing Innovative Neurotechnologies) Initiative is an ambitious project to develop innovative tools for a deeper understanding of how the brain functions in health and disease. Early programs in the National Institutes of Health BRAIN Initiative focus on tools for next-generation imaging and recording, studies of cell diversity and cell census, and integrative approaches to circuit function. In all of these efforts, cell biologists can play a leading role.

  5. Examination of near-wall hindered Brownian diffusion of nanoparticles: Experimental comparison to theories by Brenner (1961) and Goldman et al. (1967)

    International Nuclear Information System (INIS)

    Choi, C. K.; Margraves, C. H.; Kihm, K. D.

    2007-01-01

    Multilayered distributions of hindered mean square displacement (MSD) for nanoparticles are measured in the near-wall region within 500 nm from the solid surface using total internal reflection fluorescence microscopy, an evanescent wave microscopic imaging technique. Examined particles are yellow-green (505/515) polystyrene fluorescent nanospheres of 100, 250, and 500 nm radii with a specific gravity of 1.055. To ensure the measurement accuracy, special care is taken to minimize photobleaching of fluorescent particles by adding neutral density filters to optimally reduce the excitation power. The experimental results for parallel MSDs to the solid surface validate the theory of hindered diffusion [A. J. Goldman, R. G. Cox, and H. Brenner, 'Slow viscous motion of a sphere parallel to a plane - I: Motion through a quiescent fluid', Chem. Eng. Sci. 22, 637 (1967)] of spheres based on viscous slow-down in the near-wall region. It is also reported that the effect of adding sodium chloride up to 10 mM to the solution has little effect on the parallel diffusive motion of the tested nanoparticles. Experimental evidence shows that normal MSDs, for submicroscopic charged nanoparticles, are substantially different from Einstein's 2DΔt due to the deterministic motion arising from electrostatic forces

  6. Educational background and professional participation by federal wildlife biologists: Implications for science, management, and The Wildlife Society

    Science.gov (United States)

    Schmutz, Joel A.

    2002-01-01

    Over 2,000 people are employed in wildlife biology in the United States federal government. The size of this constituency motivated me to examine the amount of formal education federal biologists have received and the extent of continuing education they undertake by reading journals or attending scientific meetings. Most federal biologists who are members of The Wildlife Society (TWS) have a graduate degree. However, one-third have only a Bachelor of Science degree, despite the current trend toward hiring people with graduate degrees. Most federal biologists are not research biologists. Numbers of journals subscribed to was positively related to educational level. Less than one-third of all wildlife biologists employed by the United States Fish and Wildlife Service are members of TWS or subscribe to any of its journals. In contrast, the majority of presenters at the TWS 2000 Annual Conference were research biologists and members of TWS. The failure of many federal wildlife biologists to read scientific literature or attend professional meetings indicates a failure to promote the importance of continuing education in the federal workplace. I identify 2 potential adverse impacts of this failing: an inability to recognize important and relevant scientific contributions and an ineffectiveness in carrying out adaptive management.

  7. Fighting for life: Religion and science in the work of fish and wildlife biologists

    Science.gov (United States)

    Geffen, Joel Phillip

    Philosophers, historians, and sociologists of science have argued that it is impossible to separate fact from value. Even so, Americans generally demand that scientists be "objective." No bias is permitted in their work. Religious motivations in particular are widely considered anathema within the halls of science. My dissertation addresses both theoretical and practical aspects concerning objectivity in science through an examination of fish and wildlife biologists. I hypothesized that they use the language of objective science as a tool to convince others to protect habitats and species. Further, I claimed that this "rhetoric of science" is employed either consciously or unconsciously on behalf of personal values, and that religious and/or spiritual values figure significantly among these. Regarding the issue's practical applications, I argued in support of Susan Longino's assertion that while subjective influences exist in science, they do not necessarily indicate that objectivity has been sacrificed. My primary methodology is ethnographic. Thirty-five biologists working in the Pacific Northwest were interviewed during the course of summer 2001. Participant ages ranged from 23 to 78. Both genders were represented, as were various ethnic and cultural backgrounds, including Native American. I used a questionnaire to guide respondents through a consistent set of open-ended queries. I organized their answers under four categories: the true, the good, the beautiful, and the holy. The first three were borrowed from the theoretical writings of philosopher Immanuel Kant. The last came from Rudolf Otto's theological work. These categories provided an excellent analytical framework. I found that the great majority of fish and wildlife biologists strive for objectivity. However, they are also informed by powerful contextual values. These are derived from environmental ethics, aesthetic preferences pertaining to ecosystem appearance and function, and visceral experiences of

  8. Demystifying animal 'personality' (or not): why individual variation matters to experimental biologists.

    Science.gov (United States)

    Roche, Dominique G; Careau, Vincent; Binning, Sandra A

    2016-12-15

    Animal 'personality', defined as repeatable inter-individual differences in behaviour, is a concept in biology that faces intense controversy. Critics argue that the field is riddled with terminological and methodological inconsistencies and lacks a sound theoretical framework. Nevertheless, experimental biologists are increasingly studying individual differences in physiology and relating these to differences in behaviour, which can lead to fascinating insights. We encourage this trend, and in this Commentary we highlight some of the benefits of estimating variation in (and covariation among) phenotypic traits at the inter- and intra-individual levels. We focus on behaviour while drawing parallels with physiological and performance-related traits. First, we outline some of the confusion surrounding the terminology used to describe repeatable inter-individual differences in behaviour. Second, we argue that acknowledging individual behavioural differences can help researchers avoid sampling and experimental bias, increase explanatory power and, ultimately, understand how selection acts on physiological traits. Third, we summarize the latest methods to collect, analyse and present data on individual trait variation. We note that, while measuring the repeatability of phenotypic traits is informative in its own right, it is only the first step towards understanding how natural selection and genetic architecture shape intra-specific variation in complex, labile traits. Thus, understanding how and why behavioural traits evolve requires linking repeatable inter-individual behavioural differences with core aspects of physiology (e.g. neurophysiology, endocrinology, energy metabolism) and evolutionary biology (e.g. selection gradients, heritability). © 2016. Published by The Company of Biologists Ltd.

  9. How in the 20th century physicists, chemists and biologists answered the question: what is life?

    International Nuclear Information System (INIS)

    Reutov, Valentin P; Schechter, A N

    2010-01-01

    The most essential achievements in 20th century biology are analyzed and the question of how throughout the last century physicists, chemists and biologists answered the question 'What is life?' is considered. The most considerable scientific achievement of 20th century biology, and perhaps of all science, is considered by many to be the discovery by biologist J Watson and physicists F Crick and M Wilkins that resulted in establishing the DNA structure. The related work of well-known scientists of the USA and Europe, E Schroedinger, L Pauling, M Perutz, J Kendrew, and of the Russian scientists N K Koltsov, N V Timofeeff-Ressovsky, G A Gamow, A M Olovnikov, is analyzed. Presently, when the structure of DNA, the process of gene expression and even the genomes of human beings are already known, scientists realize that we still do not know many of the most important things. In our opinion, the 20th century studies of nucleic acids largely ignored the principle of the cyclic organisation of DNA. In this connection, we analyze the principle of cyclicity, which in its generality may well complement the concept of the atomic structure of matter. (from the history of physics)

  10. How in the 20th century physicists, chemists and biologists answered the question: what is life?

    Energy Technology Data Exchange (ETDEWEB)

    Reutov, Valentin P [Institute for Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow (Russian Federation); Schechter, A N [National Institutes of Health, Bethesda, Maryland (United States)

    2010-07-08

    The most essential achievements in 20th century biology are analyzed and the question of how throughout the last century physicists, chemists and biologists answered the question 'What is life?' is considered. The most considerable scientific achievement of 20th century biology, and perhaps of all science, is considered by many to be the discovery by biologist J Watson and physicists F Crick and M Wilkins that resulted in establishing the DNA structure. The related work of well-known scientists of the USA and Europe, E Schroedinger, L Pauling, M Perutz, J Kendrew, and of the Russian scientists N K Koltsov, N V Timofeeff-Ressovsky, G A Gamow, A M Olovnikov, is analyzed. Presently, when the structure of DNA, the process of gene expression and even the genomes of human beings are already known, scientists realize that we still do not know many of the most important things. In our opinion, the 20th century studies of nucleic acids largely ignored the principle of the cyclic organisation of DNA. In this connection, we analyze the principle of cyclicity, which in its generality may well complement the concept of the atomic structure of matter. (from the history of physics)

  11. BioSPICE: access to the most current computational tools for biologists.

    Science.gov (United States)

    Garvey, Thomas D; Lincoln, Patrick; Pedersen, Charles John; Martin, David; Johnson, Mark

    2003-01-01

    The goal of the BioSPICE program is to create a framework that provides biologists access to the most current computational tools. At the program midpoint, the BioSPICE member community has produced a software system that comprises contributions from approximately 20 participating laboratories integrated under the BioSPICE Dashboard and a methodology for continued software integration. These contributed software modules are the BioSPICE Dashboard, a graphical environment that combines Open Agent Architecture and NetBeans software technologies in a coherent, biologist-friendly user interface. The current Dashboard permits data sources, models, simulation engines, and output displays provided by different investigators and running on different machines to work together across a distributed, heterogeneous network. Among several other features, the Dashboard enables users to create graphical workflows by configuring and connecting available BioSPICE components. Anticipated future enhancements to BioSPICE include a notebook capability that will permit researchers to browse and compile data to support model building, a biological model repository, and tools to support the development, control, and data reduction of wet-lab experiments. In addition to the BioSPICE software products, a project website supports information exchange and community building.

  12. Values and attitudes of National Wildlife Refuge managers and biologists; Report to respondents

    Science.gov (United States)

    Brinson, Ayeisha A.; Benson, Delwin E.

    2002-01-01

    The issues affecting natural resource management, the society in which natural resource management occurs, natural resource agency personnel, and the publics they serve have changed in recent decades. Previous studies of Refuge professionals in the U.S. Fish and Wildlife Service (Service) have revealed that employees lack strong commitment to the current organizational structure, were frustrated with the lack of communication within the agency and felt there was a need for strong leadership (PEER 1998, 1999). These results prompted the authors to have further questions about refuge management in the Fish and Wildlife Service. What do employees value about their agency? Is there a difference in values between refuge managers and biologists and if so, what are those differences and what influences those differences?

  13. News UK public libraries offer walk-in access to research Atoms for Peace? The Atomic Weapons Establishment and UK universities Students present their research to academics: CERN@school Science in a suitcase: Marvin and Milo visit Ethiopia Inspiring telescopes A day for everyone teaching physics 2014 Forthcoming Events

    Science.gov (United States)

    2014-05-01

    UK public libraries offer walk-in access to research Atoms for Peace? The Atomic Weapons Establishment and UK universities Students present their research to academics: CERN@school Science in a suitcase: Marvin and Milo visit Ethiopia Inspiring telescopes A day for everyone teaching physics 2014 Forthcoming Events

  14. GeneNotes – A novel information management software for biologists

    Directory of Open Access Journals (Sweden)

    Wong Wing H

    2005-02-01

    Full Text Available Abstract Background Collecting and managing information is a challenging task in a genome-wide profiling research project. Most databases and online computational tools require a direct human involvement. Information and computational results are presented in various multimedia formats (e.g., text, image, PDF, word files, etc., many of which cannot be automatically processed by computers in biologically meaningful ways. In addition, the quality of computational results is far from perfect and requires nontrivial manual examination. The timely selection, integration and interpretation of heterogeneous biological information still heavily rely on the sensibility of biologists. Biologists often feel overwhelmed by the huge amount of and the great diversity of distributed heterogeneous biological information. Description We developed an information management application called GeneNotes. GeneNotes is the first application that allows users to collect and manage multimedia biological information about genes/ESTs. GeneNotes provides an integrated environment for users to surf the Internet, collect notes for genes/ESTs, and retrieve notes. GeneNotes is supported by a server that integrates gene annotations from many major databases (e.g., HGNC, MGI, etc.. GeneNotes uses the integrated gene annotations to (a identify genes given various types of gene IDs (e.g., RefSeq ID, GenBank ID, etc., and (b provide quick views of genes. GeneNotes is free for academic usage. The program and the tutorials are available at: http://bayes.fas.harvard.edu/genenotes/. Conclusions GeneNotes provides a novel human-computer interface to assist researchers to collect and manage biological information. It also provides a platform for studying how users behave when they manipulate biological information. The results of such study can lead to innovation of more intelligent human-computer interfaces that greatly shorten the cycle of biology research.

  15. WE-G-213-02: The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who Were They and What Did They Do?

    Energy Technology Data Exchange (ETDEWEB)

    Rothenberg, L. [Memorial Sloan-Kettering Cancer Center (United States)

    2015-06-15

    Roentgen and the Birth of Modern Medical Physics – Perry Sprawls Wilhelm Roentgen is well known for his discovery of x-radiation. What is less known and appreciated is his intensive research following the discovery to determine the characteristics of the “new kind of radiation” and demonstrate its great value for medical purposes. In this presentation we will imagine ourselves in Roentgen’s mind and follow his thinking, including questions and doubts, as he designs and conducts a series of innovative experiments that provided the foundation for the rapid growth of medical physics. Learning Objectives: Become familiar with the personal characteristics and work of Prof. Roentgen that establishes him as an inspiring model for the medical physics profession. Observe the thought process and experiments that determined and demonstrated the comprehensive characteristics of x-radiation. The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who were they and what did they do? – Lawrence N. Rothenberg William David Coolidge (1873–1975) William Coolidge was born in Hudson, NY in 1873. He obtained his BS at the Massacusetts Institute of Technology in 1896. Coolidge then went to the University of Leipzig, Germany for graduate study with physicists Paul Drude and Gustave Wiedemann and received a Ph.D. in 1899. While in Germany he met Wilhelm Roentgen. Coolidge returned to the US to teach at MIT where he was associated with Arthur A. Noyes of the Chemistry Department, working on the electrical conductivity of aqueous solutions. Willis R. Whitney, under whom Coolidge had worked before going to Germany, became head of the newly formed General Electric Research Laboratory and he invited Coolidge to work with him. In 1905, Coolidge joined the staff of the GE laboratory and was associated with it for the remainder of his life. He developed ductile tungsten filaments to replace fragile carbon filaments as the material for electric light

  16. WE-G-213-00: History Symposium: Radiological Physics Pioneers: Roentgen and the AAPM Award Eponyms - William Coolidge, Edith Quimby, and Marvin Williams - Who Were They and What Did They Do?

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2015-06-15

    Roentgen and the Birth of Modern Medical Physics – Perry Sprawls Wilhelm Roentgen is well known for his discovery of x-radiation. What is less known and appreciated is his intensive research following the discovery to determine the characteristics of the “new kind of radiation” and demonstrate its great value for medical purposes. In this presentation we will imagine ourselves in Roentgen’s mind and follow his thinking, including questions and doubts, as he designs and conducts a series of innovative experiments that provided the foundation for the rapid growth of medical physics. Learning Objectives: Become familiar with the personal characteristics and work of Prof. Roentgen that establishes him as an inspiring model for the medical physics profession. Observe the thought process and experiments that determined and demonstrated the comprehensive characteristics of x-radiation. The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who were they and what did they do? – Lawrence N. Rothenberg William David Coolidge (1873–1975) William Coolidge was born in Hudson, NY in 1873. He obtained his BS at the Massacusetts Institute of Technology in 1896. Coolidge then went to the University of Leipzig, Germany for graduate study with physicists Paul Drude and Gustave Wiedemann and received a Ph.D. in 1899. While in Germany he met Wilhelm Roentgen. Coolidge returned to the US to teach at MIT where he was associated with Arthur A. Noyes of the Chemistry Department, working on the electrical conductivity of aqueous solutions. Willis R. Whitney, under whom Coolidge had worked before going to Germany, became head of the newly formed General Electric Research Laboratory and he invited Coolidge to work with him. In 1905, Coolidge joined the staff of the GE laboratory and was associated with it for the remainder of his life. He developed ductile tungsten filaments to replace fragile carbon filaments as the material for electric light

  17. WE-G-213-00: History Symposium: Radiological Physics Pioneers: Roentgen and the AAPM Award Eponyms - William Coolidge, Edith Quimby, and Marvin Williams - Who Were They and What Did They Do?

    International Nuclear Information System (INIS)

    2015-01-01

    Roentgen and the Birth of Modern Medical Physics – Perry Sprawls Wilhelm Roentgen is well known for his discovery of x-radiation. What is less known and appreciated is his intensive research following the discovery to determine the characteristics of the “new kind of radiation” and demonstrate its great value for medical purposes. In this presentation we will imagine ourselves in Roentgen’s mind and follow his thinking, including questions and doubts, as he designs and conducts a series of innovative experiments that provided the foundation for the rapid growth of medical physics. Learning Objectives: Become familiar with the personal characteristics and work of Prof. Roentgen that establishes him as an inspiring model for the medical physics profession. Observe the thought process and experiments that determined and demonstrated the comprehensive characteristics of x-radiation. The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who were they and what did they do? – Lawrence N. Rothenberg William David Coolidge (1873–1975) William Coolidge was born in Hudson, NY in 1873. He obtained his BS at the Massacusetts Institute of Technology in 1896. Coolidge then went to the University of Leipzig, Germany for graduate study with physicists Paul Drude and Gustave Wiedemann and received a Ph.D. in 1899. While in Germany he met Wilhelm Roentgen. Coolidge returned to the US to teach at MIT where he was associated with Arthur A. Noyes of the Chemistry Department, working on the electrical conductivity of aqueous solutions. Willis R. Whitney, under whom Coolidge had worked before going to Germany, became head of the newly formed General Electric Research Laboratory and he invited Coolidge to work with him. In 1905, Coolidge joined the staff of the GE laboratory and was associated with it for the remainder of his life. He developed ductile tungsten filaments to replace fragile carbon filaments as the material for electric light

  18. WE-G-213-02: The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who Were They and What Did They Do?

    International Nuclear Information System (INIS)

    Rothenberg, L.

    2015-01-01

    Roentgen and the Birth of Modern Medical Physics – Perry Sprawls Wilhelm Roentgen is well known for his discovery of x-radiation. What is less known and appreciated is his intensive research following the discovery to determine the characteristics of the “new kind of radiation” and demonstrate its great value for medical purposes. In this presentation we will imagine ourselves in Roentgen’s mind and follow his thinking, including questions and doubts, as he designs and conducts a series of innovative experiments that provided the foundation for the rapid growth of medical physics. Learning Objectives: Become familiar with the personal characteristics and work of Prof. Roentgen that establishes him as an inspiring model for the medical physics profession. Observe the thought process and experiments that determined and demonstrated the comprehensive characteristics of x-radiation. The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who were they and what did they do? – Lawrence N. Rothenberg William David Coolidge (1873–1975) William Coolidge was born in Hudson, NY in 1873. He obtained his BS at the Massacusetts Institute of Technology in 1896. Coolidge then went to the University of Leipzig, Germany for graduate study with physicists Paul Drude and Gustave Wiedemann and received a Ph.D. in 1899. While in Germany he met Wilhelm Roentgen. Coolidge returned to the US to teach at MIT where he was associated with Arthur A. Noyes of the Chemistry Department, working on the electrical conductivity of aqueous solutions. Willis R. Whitney, under whom Coolidge had worked before going to Germany, became head of the newly formed General Electric Research Laboratory and he invited Coolidge to work with him. In 1905, Coolidge joined the staff of the GE laboratory and was associated with it for the remainder of his life. He developed ductile tungsten filaments to replace fragile carbon filaments as the material for electric light

  19. Simple heuristics and rules of thumb: where psychologists and behavioural biologists might meet.

    Science.gov (United States)

    Hutchinson, John M C; Gigerenzer, Gerd

    2005-05-31

    The Centre for Adaptive Behaviour and Cognition (ABC) has hypothesised that much human decision-making can be described by simple algorithmic process models (heuristics). This paper explains this approach and relates it to research in biology on rules of thumb, which we also review. As an example of a simple heuristic, consider the lexicographic strategy of Take The Best for choosing between two alternatives: cues are searched in turn until one discriminates, then search stops and all other cues are ignored. Heuristics consist of building blocks, and building blocks exploit evolved or learned abilities such as recognition memory; it is the complexity of these abilities that allows the heuristics to be simple. Simple heuristics have an advantage in making decisions fast and with little information, and in avoiding overfitting. Furthermore, humans are observed to use simple heuristics. Simulations show that the statistical structures of different environments affect which heuristics perform better, a relationship referred to as ecological rationality. We contrast ecological rationality with the stronger claim of adaptation. Rules of thumb from biology provide clearer examples of adaptation because animals can be studied in the environments in which they evolved. The range of examples is also much more diverse. To investigate them, biologists have sometimes used similar simulation techniques to ABC, but many examples depend on empirically driven approaches. ABC's theoretical framework can be useful in connecting some of these examples, particularly the scattered literature on how information from different cues is integrated. Optimality modelling is usually used to explain less detailed aspects of behaviour but might more often be redirected to investigate rules of thumb.

  20. Ballooning for Biologists: Mission Essentials for Flying Experiments on Large NASA Balloons

    Science.gov (United States)

    Smith, David J.; Sowa, Marianne

    2017-01-01

    Despite centuries of scientific balloon flights, only a handful of experiments have produced biologically-relevant results. Yet unlike orbital spaceflight, it is much faster and cheaper to conduct biology research with balloons, sending specimens to the near space environment of Earths stratosphere. Samples can be loaded the morning of a launch and sometimes returned to the laboratory within one day after flying. The National Aeronautics and Space Administration (NASA) flies large, unmanned scientific balloons from all over the globe, with missions ranging from hours to weeks in duration. A payload in the middle portion of the stratosphere (approx. 35 km above sea level) will be exposed to an environment similar to the surface of Mars: temperatures generally around -36 C, atmospheric pressure at a thin 1 kPa, relative humidity levels <1%, and a harsh illumination of ultraviolet (UV) and cosmic radiation levels (about 100 W/sq m and 0.1 mGy/d, respectively) that can be obtained nowhere else on the surface of the Earth, including environmental chambers and particle accelerator facilities attempting to simulate space radiation effects. Considering the operational advantages of ballooning and the fidelity of space-like stressors in the stratosphere, researchers in aerobiology, astrobiology, and space biology can benefit from balloon flight experiments as an intermediary step on the extraterrestrial continuum (ground, low Earth orbit, and deep space studies). Our presentation targets biologists with no background or experience in scientific ballooning. We will provide an overview of large balloon operations, biology topics that can be uniquely addressed in the stratosphere, and a roadmap for developing payloads to fly with NASA.

  1. Evaluating sources of job satisfaction: A survey of U.S. Fish and Wildlife refuge managers and biologists

    Science.gov (United States)

    Ponds, Phadrea D.; Brinson, Ayeisha A.; Benson, Delwin

    2003-01-01

    The following summary consists of revised excerpts from the thesis study that was conducted in 2000-2002 by Ayeisha Brinson, Colorado State University (Brinson, 2002). The purpose of this report is to provide the U.S. Fish and Wildlife Service (USFWS) with additional finding related to sources of job satisfaction. Because this is a report of additional findings from a length study, the information in this report is condensed and represented without references from the original research. The literature review, methodology, and discussion from the original thesis are not presented in this report. Any questions concerning the thesis should be directed to Ayeisha Brinson, who may be reached by e-mail. The purpose of the report is to examine differences and similarities between National Wildlife Refuge managers and biologists on a selection of independent variable related to job satisfaction occupation status (being either a manager or a biologist): are managers more satisfied with their jobs than biologist? If so, what are the components of that satisfaction? What are the sources of dissatisfaction? a?|

  2. "Early Psychosis" as a mirror of biologist controversies in post-war German, Anglo-Saxon, and Soviet Psychiatry.

    Science.gov (United States)

    Rzesnitzek, Lara

    2013-01-01

    The English term "early psychosis" was coined in the 1930s to refer to feelings of irritability, loss of concentration, hypochondriac ideas, moodiness, and lassitude that were seen to precede the onset of clear-cut hallucinations and delusions. The history of thinking about "early psychosis" under names such as "latent," "masked," "mild," "simple" or "sluggish" schizophrenia before World War II and afterwards on the different sides of the Wall and the Iron Curtain reveals "early psychosis" as a mirror of quite aged international biologist controversies that are still alive today and to the same extent as they are misunderstood, are influential in their implications in today's psychiatry.

  3. Quantum Physics for Scientists and Technologists Fundamental Principles and Applications for Biologists, Chemists, Computer Scientists, and Nanotechnologists

    CERN Document Server

    Sanghera, Paul

    2011-01-01

    Presenting quantum physics for the non-physicists, Quantum Physics for Scientists and Technologists is a self-contained, cohesive, concise, yet comprehensive, story of quantum physics from the fields of science and technology, including computer science, biology, chemistry, and nanotechnology. The authors explain the concepts and phenomena in a practical fashion with only a minimum amount of math. Examples from, and references to, computer science, biology, chemistry, and nanotechnology throughout the book make the material accessible to biologists, chemists, computer scientists, and non-techn

  4. Goober: A fully integrated and user-friendly microarray data management and analysis solution for core labs and bench biologists

    Directory of Open Access Journals (Sweden)

    Luo Wen

    2009-03-01

    Full Text Available Despite the large number of software tools developed to address different areas of microarray data analysis, very few offer an all-in-one solution with little learning curve. For microarray core labs, there are even fewer software packages available to help with their routine but critical tasks, such as data quality control (QC and inventory management. We have developed a simple-to-use web portal to allow bench biologists to analyze and query complicated microarray data and related biological pathways without prior training. Both experiment-based and gene-based analysis can be easily performed, even for the first-time user, through the intuitive multi-layer design and interactive graphic links. While being friendly to inexperienced users, most parameters in Goober can be easily adjusted via drop-down menus to allow advanced users to tailor their needs and perform more complicated analysis. Moreover, we have integrated graphic pathway analysis into the website to help users examine microarray data within the relevant biological content. Goober also contains features that cover most of the common tasks in microarray core labs, such as real time array QC, data loading, array usage and inventory tracking. Overall, Goober is a complete microarray solution to help biologists instantly discover valuable information from a microarray experiment and enhance the quality and productivity of microarray core labs. The whole package is freely available at http://sourceforge.net/projects/goober. A demo web server is available at http://www.goober-array.org.

  5. Empirical investigation of the ethical reasoning of physicians and molecular biologists – the importance of the four principles of biomedical ethics

    Science.gov (United States)

    Ebbesen, Mette; Pedersen, Birthe D

    2007-01-01

    Background This study presents an empirical investigation of the ethical reasoning and ethical issues at stake in the daily work of physicians and molecular biologists in Denmark. The aim of this study was to test empirically whether there is a difference in ethical considerations and principles between Danish physicians and Danish molecular biologists, and whether the bioethical principles of the American bioethicists Tom L. Beauchamp and James F. Childress are applicable to these groups. Method This study is based on 12 semi-structured interviews with three groups of respondents: a group of oncology physicians working in a clinic at a public hospital and two groups of molecular biologists conducting basic research, one group employed at a public university and the other in a private biopharmaceutical company. Results In this sample, the authors found that oncology physicians and molecular biologists employed in a private biopharmaceutical company have the specific principle of beneficence in mind in their daily work. Both groups are motivated to help sick patients. According to the study, molecular biologists explicitly consider nonmaleficence in relation to the environment, the researchers' own health, and animal models; and only implicitly in relation to patients or human subjects. In contrast, considerations of nonmaleficence by oncology physicians relate to patients or human subjects. Physicians and molecular biologists both consider the principle of respect for autonomy as a negative obligation in the sense that informed consent of patients should be respected. However, in contrast to molecular biologists, physicians experience the principle of respect for autonomy as a positive obligation as the physician, in dialogue with the patient, offers a medical prognosis based upon the patients wishes and ideas, mutual understanding, and respect. Finally, this study discloses utilitarian characteristics in the overall conception of justice as conceived by oncology

  6. Empirical investigation of the ethical reasoning of physicians and molecular biologists – the importance of the four principles of biomedical ethics

    Directory of Open Access Journals (Sweden)

    Ebbesen Mette

    2007-10-01

    Full Text Available Abstract Background This study presents an empirical investigation of the ethical reasoning and ethical issues at stake in the daily work of physicians and molecular biologists in Denmark. The aim of this study was to test empirically whether there is a difference in ethical considerations and principles between Danish physicians and Danish molecular biologists, and whether the bioethical principles of the American bioethicists Tom L. Beauchamp and James F. Childress are applicable to these groups. Method This study is based on 12 semi-structured interviews with three groups of respondents: a group of oncology physicians working in a clinic at a public hospital and two groups of molecular biologists conducting basic research, one group employed at a public university and the other in a private biopharmaceutical company. Results In this sample, the authors found that oncology physicians and molecular biologists employed in a private biopharmaceutical company have the specific principle of beneficence in mind in their daily work. Both groups are motivated to help sick patients. According to the study, molecular biologists explicitly consider nonmaleficence in relation to the environment, the researchers' own health, and animal models; and only implicitly in relation to patients or human subjects. In contrast, considerations of nonmaleficence by oncology physicians relate to patients or human subjects. Physicians and molecular biologists both consider the principle of respect for autonomy as a negative obligation in the sense that informed consent of patients should be respected. However, in contrast to molecular biologists, physicians experience the principle of respect for autonomy as a positive obligation as the physician, in dialogue with the patient, offers a medical prognosis based upon the patients wishes and ideas, mutual understanding, and respect. Finally, this study discloses utilitarian characteristics in the overall conception of

  7. Motivating Tomorrow's Biologists

    Science.gov (United States)

    Musante, Susan

    2012-01-01

    The story of biology is far more complex and fascinating than straightforward facts or neatly labeled diagrams of structures and systems. Although exams can motivate students, the key to using these extrinsic motivators to increase student understanding lies in the way the assessments are designed and what they measure. Those involved in…

  8. Biologists Bridging Science and the Conservation Movement : The Rise of Nature Conservation and Nature Management in the Netherlands, 1850-1950

    NARCIS (Netherlands)

    van der Windt, Henny J.

    This paper investigates the importance and various roles of amateur naturalists and biologists in the conservation movement between 1850 and 1950, in particular in the Netherlands. It is concluded that biological sciences were important resources for Dutch nature conservation, although the extent of

  9. Environmental radiation effects. A need to question old paradigms and to enhance collaboration between radiation biologists and radiation ecologists

    International Nuclear Information System (INIS)

    Hinton, T.G.; Whicker, F.W.

    2003-01-01

    The radiological sciences are a real enigma- the maturity and depth of understanding concerning human dosimetry contrasts sharply with our shallow understanding about radiological effects to biota. The richness of the radiological sciences is apparent by looking at the refinements made to the fundamental unit used in human dosimetry. The radiological sciences have developed to where probabilistic risk factors can now be applied that predict specific deleterious effects to humans per unit dose. And yet, these same radiological sciences that have made such advances in human dosimetry, are primitive when effects to biota are concerned. There are no specialized units, no agreed upon weighting factors, no factors that account for distributions within an organism's body, and certainly no risk factors. There are no internationally agreed upon criteria or policies that explicitly address protection of the environment from ionizing radiation. There is not even agreement as to what endpoint should be measured to quantify an environmental effect. The bold aspect of the ICRP framework is the inclusion of sub-lethal effects (reduced reproductive success, scorable DNA damage) as endpoints. A major research consortium funded by the European Union, is also recommending that cytogenetic damage be used as an effect endpoint. The inclusion of sub-lethal endpoints begs for a linkage between molecular effects and those observed in individuals and populations. To do so, will require a strengthening of what has traditionally been separated disciplines of radiation biology and radiation ecology. The impacts of phenomena studied in the petri dishes of radiation biologists (such as genomic instability, adaptive response, and bystander effects) need to be explored and correlated to effects observed in whole organisms and populations, in collaboration with radiation ecologists. (M. Suetake)

  10. Charged Particles are Prevented from Going Faster than the Speed of Light by Light Itself: A Biophysical Cell Biologist's Contribution to Physics

    International Nuclear Information System (INIS)

    Wayne, R.

    2010-01-01

    Investigations of living organisms have led biologists and physicians to introduce fundamental concepts, including Brownian motion, the First Law of Thermodynamics, Poiseuille's Law of fluid flow, and Fick's Law of diffusion into physics. Given the prominence of viscous forces within and around cells and the experience of identifying and quantifying such resistive forces, biophysical cell biologists have an unique perspective in discovering the viscous forces that cause moving particles to respond to an applied force in a nonlinear manner. Using my experience as a biophysical cell biologist, I show that in any space consisting of a photon gas with a temperature above absolute zero, Doppler-shifted photons exert a velocity-dependent viscous force on moving charged particles. This viscous force prevents charged particles from exceeding the speed of light. Consequently, light itself prevents charged particles from moving faster than the speed of light. This interpretation provides a testable alternative to the interpretation provided by the Special Theory of Relativity, which contends that particles are prevented from exceeding the speed of light as a result of the relativity of time. (author)

  11. Tonometría Goldmann versus tonometría de Pascal en pacientes poscirugía refractiva con LASIK Results of Goldman tonometry vs Pascal tonometry in patients after the refractive surgery with LASIK

    Directory of Open Access Journals (Sweden)

    Ileana González Silverio

    2009-06-01

    Full Text Available OBJETIVO: Comparar las cifras de presión intraocular obtenidas mediante el tonómetro de aplanación de Goldmann y el tonómetro de contorno dinámico de Pascal, así como la variación del espesor corneal central, antes y después de la cirugía refractiva con LASIK y así establecer la relación entre los dos tonómetros. MÉTODOS: Se estudiaron 74 pacientes (140 ojos, mayores de 21 años, con miopía estable (de -1 dioptrías a -10 dioptrías, defecto cilíndrico inferior a -3 dioptrías y espesor corneal central menor de 480 micras. Los pacientes fueron intervenidos con excímer láser (técnica de LASIK, en el Servicio de Cirugía Refractiva del Instituto Cubano de Oftalmología "Ramón Pando Ferrer", de diciembre de 2006 a marzo de 2007, con un seguimiento posoperatorio de 1 año, aunque se estimó el comportamiento de las variables al mes de la cirugía. RESULTADOS: Predominó discretamente el sexo femenino, el grupo de edad de 21 a 39 años constituyó el 81 %, y la miopía moderada en 74 ojos el 52,8 %. El valor de la presión intraocular con tonómetro de contorno dinámico superó al obtenido con el de Goldmann en 2 mm Hg en el preoperatorio y en 3,7 mm Hg en el posoperatorio. Se correlacionó la variación del espesor corneal posterior al LASIK y la presión intraocular según el tonómetro utlizado. CONCLUSIONES: Los valores de la presión con el tonómetro de Pascal son más confiables que los obtenidos con el tonómetro de aplanación de Goldmann, cuando el espesor corneal central se aleja de lo estipulado como normal.OBJECTIVES: To compare the intraocular pressure figures obtained with Goldman applanation tonometer and with Pascal dynamic contour tonometer, as well as the central corneal thickness variation before and after the refractive surgery with LASIK, and to set the relationship between both tonometers. METHODS: Seventy four patients (140 eyes aged over 21 years, with stable myopia (-1 to -10 dioptres, cylinder defect

  12. T198. A SCHIZOPHRENIA-LIKE BIRTH SEASONALITY AMONG MATHEMATICIANS AND AN OPPOSITE SEASONALITY AMONG BIOLOGISTS: MORE EVIDENCE IMPLICATING BIMODAL RHYTHMS OF GENERAL BIRTHS

    Science.gov (United States)

    Marzullo, Giovanni

    2018-01-01

    -20th century born American scientists and among yet earlier European biologists and mathematicians. Results A group representing 1,925 American scientists showed the SCZ-resistance, GP2-coincident seasonality. However, this effect proved to be mostly due to biologists because biochemists, chemists, and physicists showed gradually less seasonality while mathematicians suggested an altogether artist-like, GP1-coincident seasonality. This intimation of a biologist-mathematician antithesis was pursued with an investigation of most major figures in the history of the two sciences from the 15th to the early-20th century. The two groups, numbering 576 mathematicians and 787 biologists, shared the same mean decade of birth, the 1780s, and essentially the same geographic origin in Western Europe. The mathematicians showed a very significant SCZ liability-like, GP1-coincident seasonality while the biologists showed an even more significant SCZ resistance-like, GP2-coincident seasonality. The latter effect was particularly strong among naturalists, anatomists and other groups representing biological “observationalism” as opposed to “experimentalism.” Discussion The findings are discussed in light of a) new evidence that the annual photoperiod is indeed alone responsible for both peaks of general births, with the GP1 and the GP2 being caused by maternal periconceptional exposure to, respectively, the summer-solstice sunlight maximum and the winter-solstice minimum, and b) an approach/withdrawal theory of lateralization of basic emotions where the left cerebral cortex would handle external stimuli eliciting complacent emotions towards external realities while the right cortex would handle internal stimuli eliciting disdain for those realities.

  13. ‘Early Psychosis’ as a Mirror of Biologist Controversies in Post-WarGerman, Anglo-Saxon and Soviet Psychiatry

    Directory of Open Access Journals (Sweden)

    Lara eRzesnitzek

    2013-07-01

    Full Text Available The English term ‘early psychosis’ was coined in the 1930s to refer to feelings of irritability, loss of concentration, hypochondriac ideas, moodiness and lassitude that were seen to precede the onset of clear-cut hallucinations and delusions. The history of thinking about ‘early psychosis’ under names such as ‘latent’, ‘masked’, ‘mild’, ‘simple’ or ‘sluggish’ schizophrenia before World War II and afterwards on the different sides of the Wall and the Iron Curtain reveals ‘early psychosis’ as a mirror of quite aged international biologist controversies that are still alive today and to the same extent as they are misunderstood, are influential in their implications in today’s psychiatry.

  14. Journey of a molecular biologist.

    Science.gov (United States)

    Nomura, Masayasu

    2011-01-01

    My journey into a research career began in fermentation biochemistry in an applied science department during the difficult post-World War II time in Japan. Subsequently, my desire to do research in basic science developed. I was fortunate to be a postdoctoral fellow in the United States during the early days of molecular biology. From 1957 to 1960, I worked with three pioneers of molecular biology, Sol Spiegelman, James Watson, and Seymour Benzer. These experiences helped me develop into a basic research scientist. My initial research projects at Osaka University, and subsequently at the University of Wisconsin, Madison, were on the mode of action of colicins as well as on mRNA and ribosomes. Following success in the reconstitution of ribosomal subunits, my efforts focused more on ribosomes, initially on the aspects of structure, function, and in vitro assembly, such as the construction of the 30S subunit assembly map. After this, my laboratory studied the regulation of the synthesis of ribosomes and ribosomal components in Escherichia coli. Our achievements included the discovery of translational feedback regulation of ribosomal protein synthesis and the identification of several repressor ribosomal proteins used in this regulation. In 1984, I moved to the University of California, Irvine, and initiated research on rRNA transcription by RNA polymerase I in the yeast Saccharomyces cerevisiae. The use of yeast genetics combined with biochemistry allowed us to identify genes uniquely involved in rRNA synthesis and to elucidate the mechanism of initiation of transcription. This essay is a reflection on my life as a research scientist.

  15. Reproducible Bioinformatics Research for Biologists

    Science.gov (United States)

    This book chapter describes the current Big Data problem in Bioinformatics and the resulting issues with performing reproducible computational research. The core of the chapter provides guidelines and summaries of current tools/techniques that a noncomputational researcher would need to learn to pe...

  16. NMR for chemists and biologists

    CERN Document Server

    Carbajo, Rodrigo J

    2013-01-01

    This book offers a concise introduction to the field of nuclear magnetic resonance or NMR. It presents the basic foundations of NMR in a non-mathematical way and provides an overview of both recent and important biological applications of NMR.

  17. WImpiBLAST: web interface for mpiBLAST to help biologists perform large-scale annotation using high performance computing.

    Directory of Open Access Journals (Sweden)

    Parichit Sharma

    Full Text Available The function of a newly sequenced gene can be discovered by determining its sequence homology with known proteins. BLAST is the most extensively used sequence analysis program for sequence similarity search in large databases of sequences. With the advent of next generation sequencing technologies it has now become possible to study genes and their expression at a genome-wide scale through RNA-seq and metagenome sequencing experiments. Functional annotation of all the genes is done by sequence similarity search against multiple protein databases. This annotation task is computationally very intensive and can take days to obtain complete results. The program mpiBLAST, an open-source parallelization of BLAST that achieves superlinear speedup, can be used to accelerate large-scale annotation by using supercomputers and high performance computing (HPC clusters. Although many parallel bioinformatics applications using the Message Passing Interface (MPI are available in the public domain, researchers are reluctant to use them due to lack of expertise in the Linux command line and relevant programming experience. With these limitations, it becomes difficult for biologists to use mpiBLAST for accelerating annotation. No web interface is available in the open-source domain for mpiBLAST. We have developed WImpiBLAST, a user-friendly open-source web interface for parallel BLAST searches. It is implemented in Struts 1.3 using a Java backbone and runs atop the open-source Apache Tomcat Server. WImpiBLAST supports script creation and job submission features and also provides a robust job management interface for system administrators. It combines script creation and modification features with job monitoring and management through the Torque resource manager on a Linux-based HPC cluster. Use case information highlights the acceleration of annotation analysis achieved by using WImpiBLAST. Here, we describe the WImpiBLAST web interface features and architecture

  18. WImpiBLAST: web interface for mpiBLAST to help biologists perform large-scale annotation using high performance computing.

    Science.gov (United States)

    Sharma, Parichit; Mantri, Shrikant S

    2014-01-01

    The function of a newly sequenced gene can be discovered by determining its sequence homology with known proteins. BLAST is the most extensively used sequence analysis program for sequence similarity search in large databases of sequences. With the advent of next generation sequencing technologies it has now become possible to study genes and their expression at a genome-wide scale through RNA-seq and metagenome sequencing experiments. Functional annotation of all the genes is done by sequence similarity search against multiple protein databases. This annotation task is computationally very intensive and can take days to obtain complete results. The program mpiBLAST, an open-source parallelization of BLAST that achieves superlinear speedup, can be used to accelerate large-scale annotation by using supercomputers and high performance computing (HPC) clusters. Although many parallel bioinformatics applications using the Message Passing Interface (MPI) are available in the public domain, researchers are reluctant to use them due to lack of expertise in the Linux command line and relevant programming experience. With these limitations, it becomes difficult for biologists to use mpiBLAST for accelerating annotation. No web interface is available in the open-source domain for mpiBLAST. We have developed WImpiBLAST, a user-friendly open-source web interface for parallel BLAST searches. It is implemented in Struts 1.3 using a Java backbone and runs atop the open-source Apache Tomcat Server. WImpiBLAST supports script creation and job submission features and also provides a robust job management interface for system administrators. It combines script creation and modification features with job monitoring and management through the Torque resource manager on a Linux-based HPC cluster. Use case information highlights the acceleration of annotation analysis achieved by using WImpiBLAST. Here, we describe the WImpiBLAST web interface features and architecture, explain design

  19. An appreciation of Ralph Marvin Steinman (1943–2011)

    Science.gov (United States)

    Moberg, Carol L.

    2011-01-01

    Ralph Steinman, an editor at the Journal of Experimental Medicine since 1978, shared the 2011 Nobel Prize in Physiology or Medicine for his discovery of dendritic cells (DCs) and their role in immunity. Ralph never knew. He died of pancreatic cancer on September 30, 3 days before the Nobel announcement. Unaware of his death at the time of their announcement, the Nobel Committee made the unprecedented decision that his award would stand. Ralph was the consummate physician-scientist to the end. After his diagnosis, he actively participated in his 4.5 years of treatments, creating experimental therapies using his own DCs in conjunction with the therapies devised by his physicians, all the while traveling, lecturing, and most of all pursuing new investigations in his laboratory. For 38 years—from his discovery of DCs to his Nobel Prize—Ralph pioneered the criteria and methods used to identify, isolate, grow, and study DCs. He and his colleagues demonstrated that DCs are initiators of immunity and regulators of tolerance. In his most recent studies, Ralph was harnessing the specialized features of DCs to design improved vaccines. The following synopsis describes some of his seminal discoveries. PMID:22216460

  20. Sanity, Science, and Survival: A Conservation with Marvin L. Goldberger.

    Science.gov (United States)

    Davidson, Mark

    1985-01-01

    The president of the California Institute of Technology speaks out against the arms race. He discusses worthwhile scientific-technological projects that could be pursued with money presently used for weapons. There are no technical solutions to arms control issues. The solution depends upon a change of human attitude. Education's role is…

  1. Modular Affective Reasoning-Based Versatile Introspective Architecture (MARVIN)

    National Research Council Canada - National Science Library

    Reilly, Scott N; Guarino, Sean; Reposa, Mike

    2008-01-01

    Report developed under SBIR Contract for Topic #SB072-009. In this Phase I study, we demonstrated that affect-inspired, self-aware mechanisms can significantly improve the performance of computational systems in cases of limited resources...

  2. An Evaluation of the Carbon Sequestration Potential of the Cambro-Ordovician Strata of the Illinois and Michigan Basins. Part 1. Evaluation of Phase 2 CO2 Injection Testing in the Deep Saline Gunter Sandstone Reservoir (Cambro-Ordovician Knox Group), Marvin Blan No. 1 Hancock County, Kentucky Part 2. Time-lapse Three-Dimensional Vertical Seismic Profile (3D-VSP) of Sequestration Target Interval with Injected Fluids

    Energy Technology Data Exchange (ETDEWEB)

    Bowersox, Richard [Univ. of Illinois, Champaign, IL (United States); Hickman, John [Univ. of Illinois, Champaign, IL (United States); Leetaru, Hannes [Univ. of Illinois, Champaign, IL (United States)

    2012-12-20

    Part 1 of this report focuses on results of the western Kentucky carbon storage test, and provides a basis for evaluating injection and storage of supercritical CO2 in Cambro-Ordovician carbonate reservoirs throughout the U.S. Midcontinent. This test demonstrated that the Cambro- Ordovician Knox Group, including the Beekmantown Dolomite, Gunter Sandstone, and Copper Ridge Dolomite in stratigraphic succession from shallowest to deepest, had reservoir properties suitable for supercritical CO2 storage in a deep saline reservoir hosted in carbonate rocks, and that strata with properties sufficient for long-term confinement of supercritical CO2 were present in the deep subsurface. Injection testing with brine and CO2 was completed in two phases. The first phase, a joint project by the Kentucky Geological Survey and the Western Kentucky Carbon Storage Foundation, drilled the Marvin Blan No. 1 carbon storage research well and tested the entire Knox Group section in the open borehole – including the Beekmantown Dolomite, Gunter Sandstone, and Copper Ridge Dolomite – at 1152–2255 m, below casing cemented at 1116 m. During Phase 1 injection testing, most of the 297 tonnes of supercritical CO2 was displaced into porous and permeable sections of the lowermost Beekmantown below 1463 m and Gunter. The wellbore was then temporarily abandoned with a retrievable bridge plug in casing at 1105 m and two downhole pressure-temperature monitoring gauges below the bridge plug pending subsequent testing. Pressure and temperature data were recorded every minute for slightly more than a year, providing a unique record of subsurface reservoir conditions in the Knox. In contrast, Phase 2 testing, this study, tested a mechanically-isolated dolomitic-sandstone interval in the Gunter.

  3. Radiation biology for the non-biologist

    International Nuclear Information System (INIS)

    Myers, D.K.

    1978-06-01

    This colloquium introduces some of the general concepts used in cell biology and in the study of the effects of ionizing radiation on living organisms. The present research activities in radiation biology in the Biology Branch at the Chalk River Nuclear Laboratories cover a broad range of interests in the entire chain of events by which the initial radiation-induced changes in the living cell are translated into significant biological effects, including the eventual production of cancers and hereditary defects. The main theme of these research activities is an understanding of the mechanisms by which radiation damage to DNA (the carrier of hereditary information in all living organisms) can be actively repaired by the living cell. Advances in our understanding of these processes have broad implications for other areas of biology but also bear directly on the assessment of the biological hazards of ionizing radiation. The colloquium concludes with a brief discussion of the hazards of low-level radiation. (author)

  4. Biodiversities and habitabilities : a biologist view

    Science.gov (United States)

    Maurel, Marie-Christine

    2015-07-01

    If life were to again take the path it followed billion years ago, nobody can certify that it would take the same path, leading to the same species, the same types of cells, the same organisation. This implies that if life exists - or existed - elsewhere, benefiting from the same initial planetary conditions, it most likely does would not have the same history, or would not have followed the same itinerary. Thus, how can we possibly recognize and/or identify something new, probably completely new that we are unable to conceive and/or to conceptualize? From a materialistic point of view, there is no frontier between what is alive and what is not; this is a basic question for the biology community, mainly via the question of viruses and viroids. It is thus very ambiguous to define the meaning of biomarkers, and even more to search for life elsewhere based strictly on the observations of what we know occurs on Earth. Just as what is 'pathological' in biology provides us with an insight on what is 'normal', the space that lies at the border between the living and the non-living will maybe allow us to envisage other forms of life (that we cannot imagine to-day).

  5. Bringing LTL Model Checking to Biologists

    OpenAIRE

    Ahmed, Z; Benque, D; Berezin, S; Dahl, ACE; Fisher, Jasmin; Hall, Benjamin Andrew; Ishtiaq, S; Nanavati, J; Piterman, N; Riechert, M; Skoblov, N

    2017-01-01

    The BioModelAnalyzer (BMA) is a web based tool for the development of discrete models of biological systems. Through a graphical user interface, it allows rapid development of complex models of gene and protein interaction networks and stability analysis without requiring users to be proficient computer programmers. Whilst stability is a useful specification for testing many systems, testing temporal specifications in BMA presently requires the user to perform simulations. Here we describe th...

  6. Genetics of asthma: a molecular biologist perspective

    OpenAIRE

    Ghosh Balaram; Kumar Amrendra

    2009-01-01

    Abstract Asthma belongs to the category of classical allergic diseases which generally arise due to IgE mediated hypersensitivity to environmental triggers. Since its prevalence is very high in developed or urbanized societies it is also referred to as "disease of civilizations". Due to its increased prevalence among related individuals, it was understood quite long back that it is a genetic disorder. Well designed epidemiological studies reinforced these views. The advent of modern biologica...

  7. Interactive visualization tools for the structural biologist.

    Science.gov (United States)

    Porebski, Benjamin T; Ho, Bosco K; Buckle, Ashley M

    2013-10-01

    In structural biology, management of a large number of Protein Data Bank (PDB) files and raw X-ray diffraction images often presents a major organizational problem. Existing software packages that manipulate these file types were not designed for these kinds of file-management tasks. This is typically encountered when browsing through a folder of hundreds of X-ray images, with the aim of rapidly inspecting the diffraction quality of a data set. To solve this problem, a useful functionality of the Macintosh operating system (OSX) has been exploited that allows custom visualization plugins to be attached to certain file types. Software plugins have been developed for diffraction images and PDB files, which in many scenarios can save considerable time and effort. The direct visualization of diffraction images and PDB structures in the file browser can be used to identify key files of interest simply by scrolling through a list of files.

  8. The Live Universe. A Biologist's Perspective

    Directory of Open Access Journals (Sweden)

    Ricardo B. Ferreira

    2017-09-01

    Full Text Available Astrobiology looks at all aspects related to life in places other than the Earth, including its biomolecular building blocks and suitable environmental conditions. In the present article, a different approach is followed: a comparative analysis between Astronomy and Biology as discrete domains of science. Remarkable similarities exist between these two apparently widely separated and multidisciplinary fields. Both are driven, from beginning to end, by thermodynamics. Their evolution is studied to a very reasonable degree of accuracy, from beginning to the present day, by analyzing data which were “frozen” in the past. Yet we cannot predict where and how they will go from here. A major difference is that in Biology, unlike Astronomy, we can see and analyse the present (or, more accurately, the immediate past. While the Big Bang is widely accepted as the origin of our universe, the debate about its ultimate fate is far from settled. A plethora of cosmological models has been proposed, many involving the concept of a multiuniverse. The observation that the rate of expansion of the universe is apparently accelerating further boosts the discussion. Entropy may act as a driving force behind the increasing rate of expansion, with nothingness as the maximum possible entropy our universe gets. Using biological systems as an analogy and adopting a broad definition for life, we may speculate the existence of a living multiuniverse, capable of natural evolution, in which each individual universe spontaneously goes through birth, development, reproduction, aging and death. The possible roles of supermassive black holes (SMBHs and human-like intelligence on the future evolution of our universe are briefly discussed.

  9. Effects of Pinus flexilis on the dynamics and structure of plant communities on the northern Rocky Mountain front, and, Training biologists for emerging niches in non-traditional jobs

    Science.gov (United States)

    Baumeister, Dayna Marie

    been characterized by invasion of P. flexilis and subsequent shifts in understory species composition apparently facilitated by P. flexilis. Lastly, I examined the role of the emerging science of biomimicry in providing employment for biologists. Biomimicry as a discipline seeks design solutions inspired by nature. Industries employing this tool require biologists with an understanding of biology from a functional perspective, good communication skills, and a background in applied natural history.

  10. Processos da vida, processos da matéria: os diferentes sentidos de natureza entre biólogos e físicos Life processes, matter processes: the different meanings of nature among biologists and physicists

    Directory of Open Access Journals (Sweden)

    Carolina Lima Alves Belo

    2012-12-01

    Full Text Available Aplicamos a metodologia de análise do Discurso do Sujeito Coletivo (DSC para comparar as representações sociais relacionadas ao termo natureza em dois grupos de docentes pesquisadores - um de físicos, outro de biólogos - em uma universidade pública brasileira. Foram identificadas cinco classes de discurso coletivo entre os sujeitos investigados, cada uma das quais foi expressa por ambos os grupos. Dois discursos identificados - que denominamos natureza é o natural (DSC1 e natureza é tudo (DSC2 - associam natureza ao não tocado ou originalmente feito pelo homem (DSC1 e a tudo o que compõe o universo (DSC2. Embora de maior adesão em ambos os grupos, o primeiro discurso teve uma adesão mais significativa entre os físicos; o segundo, por sua vez, foi mais frequente entre os biólogos. Dentre as classes de discursos de menor adesão, uma delas foi caracterizada pela dúvida dos sujeitos sobre o significado efetivo de natureza. Os resultados foram discutidos sob duas abordagens: (a do ponto de vista das relações entre os termos natureza e ambiente no âmbito da educação ambiental, tendo em vista a importância social dos cientistas na formação e na transmissão de conhecimentos relacionados ao assunto; e (b do ponto de vista das diferenças de fundamentos filosóficos (ontológicos e epistemológicos entre os dois grupos de cientistas da natureza.We have applied the methodology of Collective Subject Discourse (CSD analysis to compare the social representations related to the term nature in two groups of teachers-researchers - one of physicists and the other of biologists - from a Brazilian public university. Five classes of collective discourse were identified among the subjects researched, each one of them being expressed by both groups. Two discourses identified - which we labeled nature is the natural (DSC1 and nature is everything (DSC2 - associate nature to that which has not been touched or originally made by men (DSC1, and to

  11. Fundamentals of Condensed Matter Physics Marvin L. Cohen and Steven G. Louie

    Energy Technology Data Exchange (ETDEWEB)

    Devanathan, Ram

    2017-06-01

    This graduate level textbook on Condensed Matter Physics is written lucidly by two leading luminaries in this field. The volume draws its material from the graduate course in condensed matter physics that has been offered by the authors for several decades at the University of California, Berkeley. Cohen and Louie have done an admirable job of guiding the reader gradually from elementary concepts to advanced topics. The book is divided into four main parts that have four chapters each. Chapter 1 presents models of solids in terms of interacting atoms, which is appropriate for the ground state, and excitations to describe collective effects. Chapter 2 deals with the properties of electrons in crystalline materials. The authors introduce the Born-Oppenheimer approximation and then proceed to the periodic potential approximation. Chapter 3 discusses energy bands in materials and covers concepts from the free electron model to the tight binding model and periodic boundary conditions. Chapter 4 starts with fixed atomic cores and introduces lattice vibrations, phonons, and the concept of density of states. By the end of this part, the student should have a basic understanding of electrons and phonons in materials. Part II presents electron dynamics and the response of materials to external probes. Chapter 5 covers the effective Hamiltonian approximation and the motion of the electron under a perturbation, such as an external field. The discussion moves to many-electron interactions and the exchange-correlation energy in Chapter 6, the widely-used Density Functional Theory (DFT) in chapter 7, and the dielectric response function in Chapter 8. The next two parts of the book cover advanced topics. Part III begins with a discussion of the response of materials to photons in Chapter 9. Chapter 10 goes into the details of electron-phonon interactions in different materials and introduces the polaron. Chapter 11 presents electron dynamics in a magnetic field and Chapter 12 discusses electrical and thermal transport in materials. Part IV takes the reader further into many body effects, superconductivity, and nanoscale materials. The authors introduce Feynman diagrams and many-body perturbation theory in Chapter 13, theories of superconductivity in Chapter 14, magnetism in Chapter 15, and low dimensional systems in Chapter 16. The first two parts are required reading for the beginner planning to perform DFT calculations. The advanced student interested in conducting research in condensed matter physics will benefit from continuing on to the last two parts. There is a set of problems at the end of each part. The narrative is aided by equations and detailed figures. References at the end of the book direct the reader to relevant books and review articles for each chapter. The inside covers include a periodic table and a useful list of fundamental physical constants. The authors present the underlying mathematics elegantly, which makes the textbook quite readable for those with a good mathematical background. Students lacking a firm footing in math will find the terrain rough after Chapter 1. This field has seen many good undergraduate textbooks including those by Kittel and by Ashcroft and Mermin. This volume fills the need for a rigorous graduate level textbook, and is a required addition to the bookshelf of every condensed matter physicist. Cohen and Louie have brought refreshing clarity to a challenging subject and made it eminently accessible to the motivated student.

  12. 78 FR 26407 - Goldman Sachs Trust II, et al.; Notice of Application

    Science.gov (United States)

    2013-05-06

    ... change is in the best interests of the Subadvised Fund and its shareholders, and does not involve a... permit them to enter into and materially amend subadvisory agreements without shareholder approval and... Commission orders a hearing. Interested persons may request a hearing by writing to the Commission's...

  13. Counterregulation in female obese emotional eaters: Schachter, Goldman and Gordon's test of psychosomatic theory revisited

    NARCIS (Netherlands)

    Strien, T. van; Ouwens, M.A.

    2003-01-01

    In a sample of 31 obese women, the moderating role of restrained, emotional, and external eating (as was measured by the DEBQ) on the relationship between food deprivation and food intake was studied by examining the prediction of grams of cookies eaten by the preload and degree of restrained,

  14. Rethinking Physics for Biologists: A design-based research approach

    Science.gov (United States)

    Sawtelle, Vashti

    2015-03-01

    Biology majors at the University of Maryland are required to take courses in biology, chemistry, and physics - but they often see these courses as disconnected. Over the past three years the NEXUS/Physics course has been working to develop an interdisciplinary learning environment that bridges the disciplinary domains of biology and physics. Across the three years we have gone from teaching in a small class with one instructor to teaching in a large lecture hall with multiple instructors. We have used a design-based research approach to support critical reflection of the course at multiple-time scales. In this presentation I will detail our process of collecting systematic data, listening to and valuing students' reasoning, and bridging diverse perspectives led. I will demonstrate how this process led to improved curricular design, refined assessment objectives, and new design heuristics. This work is supported by NSF-TUES DUE 11-22818, the HHMI NEXUS grant, and a NSF Graduate Research Fellowship (DGE 0750616).

  15. Microbial proteomics: a mass spectrometry primer for biologists

    Directory of Open Access Journals (Sweden)

    Graham Ciaren

    2007-08-01

    Full Text Available Abstract It is now more than 10 years since the publication of the first microbial genome sequence and science is now moving towards a post genomic era with transcriptomics and proteomics offering insights into cellular processes and function. The ability to assess the entire protein network of a cell at a given spatial or temporal point will have a profound effect upon microbial science as the function of proteins is inextricably linked to phenotype. Whilst such a situation is still beyond current technologies rapid advances in mass spectrometry, bioinformatics and protein separation technologies have produced a step change in our current proteomic capabilities. Subsequently a small, but steadily growing, number of groups are taking advantage of this cutting edge technology to discover more about the physiology and metabolism of microorganisms. From this research it will be possible to move towards a systems biology understanding of a microorganism. Where upon researchers can build a comprehensive cellular map for each microorganism that links an accurately annotated genome sequence to gene expression data, at a transcriptomic and proteomic level. In order for microbiologists to embrace the potential that proteomics offers, an understanding of a variety of analytical tools is required. The aim of this review is to provide a basic overview of mass spectrometry (MS and its application to protein identification. In addition we will describe how the protein complexity of microbial samples can be reduced by gel-based and gel-free methodologies prior to analysis by MS. Finally in order to illustrate the power of microbial proteomics a case study of its current application within the Bacilliaceae is given together with a description of the emerging discipline of metaproteomics.

  16. Putting computational modeling at the fingertips of bench biologists

    DEFF Research Database (Denmark)

    Sonnenschein, Nikolaus; Herrgard, Markus

    Communication is key in successful collaborations between theoretical and experimental life scientists. In our line of work we integrate physiological and systems-level data of cell factories with constraint-based Modeling approaches to predict suitable targets for metabolic engineering. The most......-level programming environment Mathematica and an open source metabolic modeling package (MASS Toolbox) to quickly prototype maps and other interactive widgets. In the long term, we would like to make those publicly accessible using open web technologies....

  17. What every conservation biologist should know about economic theory.

    Science.gov (United States)

    Gowdy, John; Hall, Charles; Klitgaard, Kent; Krall, Lisi

    2010-12-01

    The last century has seen the ascendance of a core economic model, which we will refer to as Walrasian economics. This model is driven by the psychological assumptions that humans act only in a self-referential and narrowly rational way and that production can be described as a self-contained circular flow between firms and households. These assumptions have critical implications for the way economics is used to inform conservation biology. Yet the Walrasian model is inconsistent with a large body of empirical evidence about actual human behavior, and it violates a number of basic physical laws. Research in behavioral science and neuroscience shows that humans are uniquely social animals and not self-centered rational economic beings. Economic production is subject to physical laws including the laws of thermodynamics and mass balance. In addition, some contemporary economic theory, spurred by exciting new research in human behavior and a wealth of data about the negative global impact of the human economy on natural systems, is moving toward a world view that places consumption and production squarely in its behavioral and biophysical context. We argue that abandoning the straightjacket of the Walrasian core is essential to further progress in understanding the complex, coupled interactions between the human economy and the natural world. We call for a new framework for economic theory and policy that is consistent with observed human behavior, recognizes the complex and frequently irreversible interaction between human and natural systems, and directly confronts the cumulative negative effects of the human economy on the Earth's life support systems. Biophysical economics and ecological economics are two emerging economic frameworks in this movement. © 2010 Society for Conservation Biology.

  18. The Live Universe. A Biologist's Perspective

    International Nuclear Information System (INIS)

    Ferreira, Ricardo B.; Ferreira, João B.

    2017-01-01

    Astrobiology looks at all aspects related to life in places other than the Earth, including its biomolecular building blocks and suitable environmental conditions. In the present article, a different approach is followed: a comparative analysis between Astronomy and Biology as discrete domains of science. Remarkable similarities exist between these two apparently widely separated and multidisciplinary fields. Both are driven, from beginning to end, by thermodynamics. Their evolution is studied to a very reasonable degree of accuracy, from beginning to the present day, by analyzing data which were “frozen” in the past. Yet we cannot predict where and how they will go from here. A major difference is that in Biology, unlike Astronomy, we can see and analyse the present (or, more accurately, the immediate past). While the Big Bang is widely accepted as the origin of our universe, the debate about its ultimate fate is far from settled. A plethora of cosmological models has been proposed, many involving the concept of a multiuniverse. The observation that the rate of expansion of the universe is apparently accelerating further boosts the discussion. Entropy may act as a driving force behind the increasing rate of expansion, with nothingness as the maximum possible entropy our universe gets. Using biological systems as an analogy and adopting a broad definition for life, we may speculate the existence of a living multiuniverse, capable of natural evolution, in which each individual universe spontaneously goes through birth, development, reproduction, aging and death. The possible roles of supermassive black holes (SMBHs) and human-like intelligence on the future evolution of our universe are briefly discussed.

  19. A Biologist in Wonderland: The Texas Biology Textbook Adoption Hearings.

    Science.gov (United States)

    McInerney, Joseph D.

    1991-01-01

    Examines Texas adoption process, described by author as having an inordinate impact on textbook market. Creationist opposition to evolution content in biological textbooks is well organized. Author presents 10 arguments made at hearing by creationists that he describes as a monument to scientific illiteracy. Asserts that creationists' confusion of…

  20. The Live Universe. A Biologist's Perspective

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, Ricardo B. [Disease and Stress Biology, Instituto Superior de Agronomia, LEAF, Universidade de Lisboa, Lisbon (Portugal); Ferreira, João B., E-mail: rbferreira@isa.ulisboa.pt [Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Lisbon (Portugal)

    2017-09-27

    Astrobiology looks at all aspects related to life in places other than the Earth, including its biomolecular building blocks and suitable environmental conditions. In the present article, a different approach is followed: a comparative analysis between Astronomy and Biology as discrete domains of science. Remarkable similarities exist between these two apparently widely separated and multidisciplinary fields. Both are driven, from beginning to end, by thermodynamics. Their evolution is studied to a very reasonable degree of accuracy, from beginning to the present day, by analyzing data which were “frozen” in the past. Yet we cannot predict where and how they will go from here. A major difference is that in Biology, unlike Astronomy, we can see and analyse the present (or, more accurately, the immediate past). While the Big Bang is widely accepted as the origin of our universe, the debate about its ultimate fate is far from settled. A plethora of cosmological models has been proposed, many involving the concept of a multiuniverse. The observation that the rate of expansion of the universe is apparently accelerating further boosts the discussion. Entropy may act as a driving force behind the increasing rate of expansion, with nothingness as the maximum possible entropy our universe gets. Using biological systems as an analogy and adopting a broad definition for life, we may speculate the existence of a living multiuniverse, capable of natural evolution, in which each individual universe spontaneously goes through birth, development, reproduction, aging and death. The possible roles of supermassive black holes (SMBHs) and human-like intelligence on the future evolution of our universe are briefly discussed.

  1. Spas Krumov Sotirov (1929-2016 - naturalist and biologist

    Directory of Open Access Journals (Sweden)

    Ranđelović, N.

    2016-12-01

    Full Text Available Prof. dr Spas Sotirov was born on 9th January, 1929 in Dimitrovgrad, where he had finished both elementary and high school. Dr Sotirov finished his bachelor biology studies in 1954. at the Faculty of Biology in Belgrade, after which he had finished and defended his Master (1962 and PhD (1970 Theses at the same institution. His academic carrier started with his promotion into assistant professor in 1982 at the Faculty of Technology in Leskovac, where he was promoted into associate professor (1987 and finally to full professor in 1990. He was involved as an organizer of many Symposiums, scientific and specialized workshops. Among his organizing activities, one of the most significant place takes Symposium entitled One hundred years of “Flora of Niš surrounding area”, where he was plenary speaker on the subject on dr Sava Petrović. Dr Sotirov was coauthor of the capital monography “Encyclopedia od Niš”. He was author of over 50 scientific publications and books.

  2. The ethics of human cadaver organ transplantation: a biologist's viewpoint.

    Science.gov (United States)

    Emson, H E

    1987-01-01

    The rights of the various individuals involved in decision-making in cadaver organ donation are considered, and there is discussion of the relation of human cadavers to the planetary biomass. I conclude that the rights of the potential recipient should outweigh those of the other parties concerned and that education and legislation should recognise and promote this. PMID:3669037

  3. Can a biologist fix a smartphone?-Just hack it!

    Science.gov (United States)

    Kamoun, Sophien

    2017-05-08

    Biological systems integrate multiscale processes and networks and are, therefore, viewed as difficult to dissect. However, because of the clear-cut separation between the software code (the information encoded in the genome sequence) and hardware (organism), genome editors can operate as software engineers to hack biological systems without any particularly deep understanding of the complexity of the systems.

  4. Molecular biologists backing effort to map entire human genome

    International Nuclear Information System (INIS)

    Zurer, P.S.

    1988-01-01

    This article discusses how the program to map and sequence the human genome will be managed. The National Research Council (NRC) recommends that a 15-year $200-million-a-year effort to map all human genes should begin immediately. However, some people have balked at the idea, saying it is a ploy to raise money. Part of the skeptic's uneasiness stems from the involvement of the Department of Energy (DOE), an agency not often linked with biological research. The DOE's interest arises from its commitment to understanding the biological effects of nuclear radiation. Critics say it is a budget-boosting tactic. This article explains some of the arguments for and against the project and explains exactly what it would involve

  5. A view of evolution by a Christian biologist

    Directory of Open Access Journals (Sweden)

    Elizabeth Jordaan

    1984-03-01

    Full Text Available This paper, which originated as an address to a gathering of Dutch Reformed Ministers in Potchefstroom, deals with the response of a Christian to concepts of evolution. The paper looks at the concept of “the beginning”, the origin of life , genetics, mutation and natural selection, the origin of diversity or speciation, man as a biological species, the missing link (in which attention is given to various theories, and finally theories of human evolution. These include the neoteny theory, the savannah theory and the aquatic theory. Following a discussion of the various aspects of these theories, the authors go on to a discussion of the evolution of intelligence and culture, and reach the conclusion that “for a Christian, evolution may help him to understand more about God and his love and his work, and also then to have more security in the belief in God”.

  6. A view of evolution by a Christian biologist

    OpenAIRE

    Elizabeth Jordaan; G. C. Loots

    1984-01-01

    This paper, which originated as an address to a gathering of Dutch Reformed Ministers in Potchefstroom, deals with the response of a Christian to concepts of evolution. The paper looks at the concept of “the beginning”, the origin of life , genetics, mutation and natural selection, the origin of diversity or speciation, man as a biological species, the missing link (in which attention is given to various theories), and finally theories of human evolution. These include the neoteny theory, the...

  7. Engineering central metabolism – a grand challenge for plant biologists

    DEFF Research Database (Denmark)

    Sweetlove, Lee J.; Nielsen, Jens; Fernie, Alisdair R.

    2017-01-01

    The goal of increasing crop productivity and nutrient-use efficiency is being addressed by a number of ambitious research projects seeking to re-engineer photosynthetic biochemistry. Many of these projects will require the engineering of substantial changes in fluxes of central metabolism. However......, as has been amply demonstrated in simpler systems such as microbes, central metabolism is extremely difficult to rationally engineer. This is because of multiple layers of regulation that operate to maintain metabolic steady state and because of the highly connected nature of central metabolism....... In this review we discuss new approaches for metabolic engineering that have the potential to address these problems and dramatically improve the success with which we can rationally engineer central metabolism in plants. In particular, we advocate the adoption of an iterative ‘design-build-test-learn’ cycle...

  8. The domestication of nuclear spins by chemists and biologists

    CERN Document Server

    Ernst, R

    1992-01-01

    The usage of nuclear spins in chemistry and biology for exploring the structure and dynamics of matter is discussed. The main emphasis is put on the methodological aspects of multidimensional nuclear magnetic resonance (NMR) spectroscopy that are responsible for the success of this powerful analytical technique.

  9. Electron Optics for Biologists: Physical Origins of Spherical Aberrations

    Science.gov (United States)

    Geissler, Peter; Zadunaisky, Jose

    1974-01-01

    Reports on the physical origins of spherical aberrations in axially symmetric electrostatic lenses to convey the essentials of electon optics to those who must think critically about the resolution of the electron microscope. (GS)

  10. William Bateson: a biologist ahead of his time

    Indian Academy of Sciences (India)

    Unknown

    produced a distinct model and some inconsistencies between the ... ject is based remain to this day (Provine 1971). From the .... re-established, the sterility does not return in the later .... The relevance of Bateson's style of thinking to modern ...

  11. The biologist and the economist: is dialogue possible?

    Science.gov (United States)

    Keyfitz, N

    1992-06-01

    There is a need for demography to be brought into policy-making discussions. In the time of Malthus, both economists and ecologists spoke the same language and each group was receptive to and supportive of the ideas of the other. The present organization of academic life precludes interdisciplinary communication. Malthus saw the limit as food supply; today, technology seems to be the defining criteria, although access to world supplies is also unevenly distributed. Minerals were once thought to present limits, but again technology was able to generate replacements as the Green Revolution provided an option for expanding food supply. During the 1950s and 1960s, limits were perceived by Arthur Lewis, Coale, and Hoover to be in shortages of capital. Now capital is seen as a result of development and not a cause. The strongest argument for limiting population growth appears to be the stability of planetary support systems (species diversity, ozone layer, global climate, and others). Knowledge of these support systems is limited and it would be wise not to press the world's carrying capacity under such conditions. Ignorance of planetary support systems may mean that the circle may be tightening closer than we know, or that a sudden disaster is possible. It is a complex task to circumscribe boundaries to various essentials for human life. Regardless of whether there is a solution to various essentials for human life. Regardless of whether there is a solution to the known or unknown environmental problems, it is possible, easy, and reliable to reduce the population by having fewer births than deaths. Economists argue that the vagaries and uncertainties of environmental damage prevent taking environmental constraints into account, when uncertainties have always been with us. A real debate on the issues instead of disciplines talking past each other would occur if all facts and conclusions were accepted by all parties. The conclusion should be that population increases must be as small as possible with the widest distribution of family planning and the most convincing presentation of information. The assumption of all disciplines must be that limits are severe and permanent. A decade ago this was the policy. Scholars in the face of constituent ignorance and legislator's inaction must take responsibility for information creation and diffusion (classroom to media to word of mouth). Expenditure taxes need to replace income taxes.

  12. Metal pollution investigation of Goldman Park, Middletown Ohio: Evidence for steel and coal pollution in a high child use setting.

    Science.gov (United States)

    Dietrich, Matthew; Huling, Justin; Krekeler, Mark P S

    2018-03-15

    A geochemical investigation of both ballfield sediment and street sediment in a park adjacent to a major steel manufacturing site in Middletown, Ohio revealed Pb, Cu, Cr and Zn exceeded background levels, but in heterogeneous ways and in varying levels of health concern. Pb, Sn, and Zn had geoaccumulation values>2 (moderate to heavy pollutants) in street sediment samples. Cr had a geoaccumulation value>1, while Ni, W, Fe and Mn had geoaccumulation values between 1 and 0 in street sediment. Street sediment contamination factors for respective elements are Zn (10.41), Sn (5.45), Pb (4.70), Sb (3.45), Cr (3.19), W (2.59), and Mn (2.43). The notable elements with the highest factors for ball fields are Zn (1.72), Pb (1.36), Cr (0.99), V (0.95), and Mn (1.00). High correlation coefficients of known constituents of steel, such as Fe and Mo, Ni and Cr, W and Co, W and V, as well as particulate steel and coal spherule fragments found by SEM suggest probable sourcing of some of the metals from the AK Steel facility directly adjacent to the park. However, overall extensive heterogeneity of metal pollutants in the area points to the difficulties in sourcing pollutant metals, with many outside sources likely contributing as well. This study demonstrates that different sediment media can be impacted by significantly different metal pollutants even when in very close proximity to a single source and points to unrecognized complexity in urban pollution processes in the region. This study pertains to large-scale regional importance, as Middletown, Ohio is indicative of a typical post-industrial Midwestern U.S. city where limited investigation has been conducted regarding urban pollution and sourcing of materials. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. 76 FR 9630 - Notice of Public Hearing and Commission Meeting

    Science.gov (United States)

    2011-02-18

    ... involving a diversion; and (4) the request of Marvin Fetterman to reopen Docket No. 20091201. Details...--Request of Marvin Fetterman To Reopen Docket No. 20091201 Mr. Marvin Fetterman has requested that the...

  14. Databases for marine biologists and biotechnologists: The state-of-the art and prospects

    Digital Repository Service at National Institute of Oceanography (India)

    Chavan, V.S.

    Only 1% of the presently available 5000 database titles are relevant to marine biology and biotechnology. Nearly 60% of these are bibliographic in nature. There are almost no textural and numeric databases, which are the prime need of researchers...

  15. On estimating the economic value of insectivorous bats: Prospects and priorities for biologists

    Science.gov (United States)

    Boyles, Justin G.; Sole, Catherine L.; Cryan, Paul M.; McCracken, Gary F.

    2013-01-01

    Bats are among the most economically important nondomesticated mammals in the world. They are well-known pollinators and seed dispersers, but crop pest suppression is probably the most valuable ecosystem service provided by bats. Scientific literature and popular media often include reports of crop pests in the diet of bats and anecdotal or extrapolated estimates of how many insects are eaten by bats. However, quantitative estimates of the ecosystem services provided by bats in agricultural systems are rare, and the few estimates that are available are limited to a single cotton-dominated system in Texas. Despite the tremendous value for conservation and economic security of such information, surprisingly few scientific efforts have been dedicated to quantifying the economic value of bats. Here, we outline the types of information needed to better quantify the value of bats in agricultural ecosystems. Because of the complexity of the ecosystems involved, creative experimental design and innovative new methods will help advance our knowledge in this area. Experiments involving bats in agricultural systems may be needed sooner than later, before population declines associated with white-nose syndrome and wind turbines potentially render them impossible.

  16. In memorium Dr. Agatha Gijzen (1904-1995), eminent museum historian and zoo biologist

    NARCIS (Netherlands)

    Bruggen, van A.C.

    1996-01-01

    Dr Agatha Gijzen (Rotterdam *9 October 1904, Merksem/Belgium †19 February 1995) was a remarkable zoologist in more than one respect. Although her professional career, spanning more than three and a half decades, was largely spent as a staff zoologist in the service of the famous Antwerp/

  17. In memoriam Prof. Dr J.T. Wiebes (1931-1999), evolutionary biologist and systematic entomologist

    NARCIS (Netherlands)

    Bruggen, van A.C.; Achterberg, van C.

    2000-01-01

    Born on 13 September 1931 in Rotterdam, Jacobus Theodorus [Koos] Wiebes read biology at Leiden University where he obtained his Ph.D. in 1963 on studies of Indo-Australian fig wasps. He started working on spiders (Lycosidae, Pisauridae) and beetles (Carabidae, Cetoniidae, Helodidae), but he earned

  18. Making sense of biologists' teaching: Two case studies of beliefs and discourse practices

    Science.gov (United States)

    Fifield, Steven James

    1999-09-01

    Undergraduate science courses are often criticized for their overemphasis of content coverage, neglect of inquiry approaches, and misrepresentation of the nature of science. Because conventional courses are influential models for future science teachers, they are often viewed as impediments to K--12 science education reform. To effectively modify how professors teach, we first need to better understand their beliefs and practices as teachers. This is an interpretive study of how two biology professors (Jim and Sue) make sense of their classroom practices in an introductory undergraduate course. Interviews are used to analyze their beliefs about teaching, learning, and science. Discourse analysis of lectures on classical genetics is used to examine their classroom practices as situated constructions of scientific knowledge. The two professors' held distinct beliefs about teaching and learning that were intricately interwoven with their beliefs about science. Jim's beliefs were largely consistent with conventional approaches to introductory science courses. He thought that introductory courses support the development of knowledge and skills that students need before they can engage in scientific inquiry. Sarah was critical of these conventional approaches. She valued courses that foster active learning and focus on applications of biology that are relevant to students' lives. But she could not enact many of her beliefs due to situational constraints associated with the course. Instead she viewed her efforts to help students succeed in a conventional course as a way to resist her colleagues' expectations that most students cannot do well in science. Discourse analysis of the professors' lectures revealed that they both relied on narratives to represent concepts in classical genetics. These narratives of concepts were distinct from other narrative forms in technical and popular presentations of biology. The relationship among these professors' beliefs and classroom practices suggest that what scientists' believe and do as teachers should be understood as dimensions of the nature of science. From this perspective, for some science professors, science education reform may entail not simply using different instructional strategies, but doing and thinking about science in radically new ways. The implications of this perspective for educational reform are discussed.

  19. An introduction to optical super-resolution microscopy for the adventurous biologist

    Science.gov (United States)

    Vangindertael, J.; Camacho, R.; Sempels, W.; Mizuno, H.; Dedecker, P.; Janssen, K. P. F.

    2018-04-01

    Ever since the inception of light microscopy, the laws of physics have seemingly thwarted every attempt to visualize the processes of life at its most fundamental, sub-cellular, level. The diffraction limit has restricted our view to length scales well above 250 nm and in doing so, severely compromised our ability to gain true insights into many biological systems. Fortunately, continuous advancements in optics, electronics and mathematics have since provided the means to once again make physics work to our advantage. Even though some of the fundamental concepts enabling super-resolution light microscopy have been known for quite some time, practically feasible implementations have long remained elusive. It should therefore not come as a surprise that the 2014 Nobel Prize in Chemistry was awarded to the scientists who, each in their own way, contributed to transforming super-resolution microscopy from a technological tour de force to a staple of the biologist’s toolkit. By overcoming the diffraction barrier, light microscopy could once again be established as an indispensable tool in an age where the importance of understanding life at the molecular level cannot be overstated. This review strives to provide the aspiring life science researcher with an introduction to optical microscopy, starting from the fundamental concepts governing compound and fluorescent confocal microscopy to the current state-of-the-art of super-resolution microscopy techniques and their applications.

  20. The Princeton Protein Orthology Database (P-POD): a comparative genomics analysis tool for biologists.

    OpenAIRE

    Sven Heinicke; Michael S Livstone; Charles Lu; Rose Oughtred; Fan Kang; Samuel V Angiuoli; Owen White; David Botstein; Kara Dolinski

    2007-01-01

    Many biological databases that provide comparative genomics information and tools are now available on the internet. While certainly quite useful, to our knowledge none of the existing databases combine results from multiple comparative genomics methods with manually curated information from the literature. Here we describe the Princeton Protein Orthology Database (P-POD, http://ortholog.princeton.edu), a user-friendly database system that allows users to find and visualize the phylogenetic r...

  1. Bridging the gap between clinicians and systems biologists: from network biology to translational biomedical research.

    Science.gov (United States)

    Jinawath, Natini; Bunbanjerdsuk, Sacarin; Chayanupatkul, Maneerat; Ngamphaiboon, Nuttapong; Asavapanumas, Nithi; Svasti, Jisnuson; Charoensawan, Varodom

    2016-11-22

    With the wealth of data accumulated from completely sequenced genomes and other high-throughput experiments, global studies of biological systems, by simultaneously investigating multiple biological entities (e.g. genes, transcripts, proteins), has become a routine. Network representation is frequently used to capture the presence of these molecules as well as their relationship. Network biology has been widely used in molecular biology and genetics, where several network properties have been shown to be functionally important. Here, we discuss how such methodology can be useful to translational biomedical research, where scientists traditionally focus on one or a small set of genes, diseases, and drug candidates at any one time. We first give an overview of network representation frequently used in biology: what nodes and edges represent, and review its application in preclinical research to date. Using cancer as an example, we review how network biology can facilitate system-wide approaches to identify targeted small molecule inhibitors. These types of inhibitors have the potential to be more specific, resulting in high efficacy treatments with less side effects, compared to the conventional treatments such as chemotherapy. Global analysis may provide better insight into the overall picture of human diseases, as well as identify previously overlooked problems, leading to rapid advances in medicine. From the clinicians' point of view, it is necessary to bridge the gap between theoretical network biology and practical biomedical research, in order to improve the diagnosis, prevention, and treatment of the world's major diseases.

  2. The "Martes complex"-- an opportunity to bring together marten, fisher, sable, wolverine, and tayra biologists

    Science.gov (United States)

    Gilbert Proulx; Keith B. Aubry

    2014-01-01

    Recent phylogenetic studies have shown that the genus Martes is polyphyletic with respect to the Fisher (Pekania pennanti), which is more closely related to the Wolverine (Gulo gulo) and Tayra (Eira barbara) than it is to the martens. We refer to the 11 species in the genera Martes, Pekania, Gulo, and Eira as the “Martes Complex”. Because the species comprising the...

  3. Bringing high-performance computing to the biologist's workbench: approaches, applications, and challenges

    International Nuclear Information System (INIS)

    Oehmen, C S; Cannon, W R

    2008-01-01

    Data-intensive and high-performance computing are poised to significantly impact the future of biological research which is increasingly driven by the prevalence of high-throughput experimental methodologies for genome sequencing, transcriptomics, proteomics, and other areas. Large centers such as NIH's National Center for Biotechnology Information, The Institute for Genomic Research, and the DOE's Joint Genome Institute) have made extensive use of multiprocessor architectures to deal with some of the challenges of processing, storing and curating exponentially growing genomic and proteomic datasets, thus enabling users to rapidly access a growing public data source, as well as use analysis tools transparently on high-performance computing resources. Applying this computational power to single-investigator analysis, however, often relies on users to provide their own computational resources, forcing them to endure the learning curve of porting, building, and running software on multiprocessor architectures. Solving the next generation of large-scale biology challenges using multiprocessor machines-from small clusters to emerging petascale machines-can most practically be realized if this learning curve can be minimized through a combination of workflow management, data management and resource allocation as well as intuitive interfaces and compatibility with existing common data formats

  4. The Common Marine Isopod Crustacea of Puerto Rico A handbook for marine biologists

    NARCIS (Netherlands)

    Menzies, Robert J.; Glynn, Peter W.

    1968-01-01

    The collecting sites from which isopods were obtained are located around the island (see p. 84). Concentrated collecting at several depths was done in the San Juan area at Boca de Cangrejos and at La Parguera where the Institute of Marine Biology is located. Many collections were made by washing a

  5. Meet the biologists: Sour gas treatment uses biology rather than chemistry to clean things up

    Energy Technology Data Exchange (ETDEWEB)

    Budd, G.

    2003-03-01

    Basic elements of the new bio-desulfurization technology are described. The new process uses the commonly occurring bacterium, Thiobacillus, rather than chemical means to remove hydrogen sulfide from natural gas. Development of the process began some ten years ago in the Netherlands as a means to clean sewage water and purify water for beer. The application of removing hydrogen sulfide from natural gas evolved upon discovery that the process was able to convert hydrogen sulfide to sulfur. Key to the bio-desulfurization process is the Thiobacillus bacterium, which unlike other plant forms, relies on chemosynthesis (instead of photosynthesis) of hydrogen sulfide, oxygen and carbon dioxide for its energy requirements. The technology has applications in refineries as well as in gas processing plants. It is well suited for use in Canada where operations tend to be on the small scale (less than 50 tonnes per day). The portable unit can be moved to another location when production at a given well drops off.

  6. The new radiation protection ordinance from the viewpoint of the radiation biologist

    International Nuclear Information System (INIS)

    Mueller, W.U.

    2002-01-01

    Due to new results obtained for radiation induced tumour risk, an adjustment of the current radiation protection law was required. In the course of this adjustment, a number of additional modifications were introduced, some of these reasonable in the context of radiation biology, some of these understandable in a psychological/political context only. (orig.) [de

  7. Game on, science - how video game technology may help biologists tackle visualization challenges.

    Science.gov (United States)

    Lv, Zhihan; Tek, Alex; Da Silva, Franck; Empereur-mot, Charly; Chavent, Matthieu; Baaden, Marc

    2013-01-01

    The video games industry develops ever more advanced technologies to improve rendering, image quality, ergonomics and user experience of their creations providing very simple to use tools to design new games. In the molecular sciences, only a small number of experts with specialized know-how are able to design interactive visualization applications, typically static computer programs that cannot easily be modified. Are there lessons to be learned from video games? Could their technology help us explore new molecular graphics ideas and render graphics developments accessible to non-specialists? This approach points to an extension of open computer programs, not only providing access to the source code, but also delivering an easily modifiable and extensible scientific research tool. In this work, we will explore these questions using the Unity3D game engine to develop and prototype a biological network and molecular visualization application for subsequent use in research or education. We have compared several routines to represent spheres and links between them, using either built-in Unity3D features or our own implementation. These developments resulted in a stand-alone viewer capable of displaying molecular structures, surfaces, animated electrostatic field lines and biological networks with powerful, artistic and illustrative rendering methods. We consider this work as a proof of principle demonstrating that the functionalities of classical viewers and more advanced novel features could be implemented in substantially less time and with less development effort. Our prototype is easily modifiable and extensible and may serve others as starting point and platform for their developments. A webserver example, standalone versions for MacOS X, Linux and Windows, source code, screen shots, videos and documentation are available at the address: http://unitymol.sourceforge.net/.

  8. Game on, science - how video game technology may help biologists tackle visualization challenges.

    Directory of Open Access Journals (Sweden)

    Zhihan Lv

    Full Text Available The video games industry develops ever more advanced technologies to improve rendering, image quality, ergonomics and user experience of their creations providing very simple to use tools to design new games. In the molecular sciences, only a small number of experts with specialized know-how are able to design interactive visualization applications, typically static computer programs that cannot easily be modified. Are there lessons to be learned from video games? Could their technology help us explore new molecular graphics ideas and render graphics developments accessible to non-specialists? This approach points to an extension of open computer programs, not only providing access to the source code, but also delivering an easily modifiable and extensible scientific research tool. In this work, we will explore these questions using the Unity3D game engine to develop and prototype a biological network and molecular visualization application for subsequent use in research or education. We have compared several routines to represent spheres and links between them, using either built-in Unity3D features or our own implementation. These developments resulted in a stand-alone viewer capable of displaying molecular structures, surfaces, animated electrostatic field lines and biological networks with powerful, artistic and illustrative rendering methods. We consider this work as a proof of principle demonstrating that the functionalities of classical viewers and more advanced novel features could be implemented in substantially less time and with less development effort. Our prototype is easily modifiable and extensible and may serve others as starting point and platform for their developments. A webserver example, standalone versions for MacOS X, Linux and Windows, source code, screen shots, videos and documentation are available at the address: http://unitymol.sourceforge.net/.

  9. Extraction of High Quality RNA from Cannabis sativa Bast Fibres: A Vademecum for Molecular Biologists

    Directory of Open Access Journals (Sweden)

    Gea Guerriero

    2016-07-01

    Full Text Available In plants there is no universal protocol for RNA extraction, since optimizations are required depending on the species, tissues and developmental stages. Some plants/tissues are rich in secondary metabolites or synthesize thick cell walls, which hinder an efficient RNA extraction. One such example is bast fibres, long extraxylary cells characterized by a thick cellulosic cell wall. Given the economic importance of bast fibres, which are used in the textile sector, as well as in biocomposites as green substitutes of glass fibres, it is desirable to better understand their development from a molecular point of view. This knowledge favours the development of biotechnological strategies aimed at improving specific properties of bast fibres. To be able to perform high-throughput analyses, such as, for instance, transcriptomics of bast fibres, RNA extraction is a crucial and limiting step. We here detail a protocol enabling the rapid extraction of high quality RNA from the bast fibres of textile hemp, Cannabis sativa L., a multi-purpose fibre crop standing in the spotlight of research.

  10. Structural biologists capture detailed image of gene regulator’s fleeting form | Center for Cancer Research

    Science.gov (United States)

    Using an ultrafast, high-intensity radiation source called an X-ray free-electron laser (XFEL), scientists have captured an atomic-level picture of an RNA structure called a riboswitch as it reorganizes itself to regulate protein production. The structure they visualized has never before been seen, and likely exists for only milliseconds after the riboswitch first encounters its activating molecule.  Read more...  

  11. Repliek comments on "a view of evolution by a Christian biologist' 1

    Directory of Open Access Journals (Sweden)

    J. D. Kies

    1986-03-01

    Full Text Available Die Ou en Nuwe Testamente van die Bybel vorm 'n eenheid, en Christene wat uit laasgenoemde lewe, moet die uitsprake van die N T oor die OT aanvaar. Christus se eie woorde was dat man en vrou in die begin geskape is. Dit laat geen ruimte vir 'n lang evolusionére geskiedenis nie. Bowendien het Jesus gesé dat as mens nie glo wat Moses geskryf het nie, jy ook nie Sy woorde kan glo nie (Joh. 5:46,47.

  12. Crowd Sourcing for Conservation: Web 2.0 a Powerful Tool for Biologists

    Directory of Open Access Journals (Sweden)

    William E. Boyd

    2012-05-01

    Full Text Available The advent and adoption of Web 2.0 technologies offers a powerful approach to enhancing the capture of information in natural resource ecology, notably community knowledge of species distributions. Such information has previously been collected using, for example, postal surveys; these are typically inefficient, with low response rates, high costs, and requiring respondents to be spatially literate. Here we describe an example, using the Google Maps Application Programming Interface, to discuss the opportunities such tools provide to conservation biology. Toad Tracker was created as a prototype to demonstrate the utility of this technology to document the distribution of an invasive vertebrate pest species, the cane toad, within Australia. While the technological aspects of this tool are satisfactory, manager resistance towards its use raises issues around the public nature of the technology, the collaborative (non-expert role in data collection, and data ownership. We conclude in suggesting that, for such tools to be accepted by non-innovation adopters, work is required on both the technological aspects and, importantly, a cultural change is required to create an environment of acceptance of the shifting relationship between authority, expertise and knowledge.

  13. Implementation of the NMR CHEmical Shift Covariance Analysis (CHESCA): A Chemical Biologist's Approach to Allostery.

    Science.gov (United States)

    Boulton, Stephen; Selvaratnam, Rajeevan; Ahmed, Rashik; Melacini, Giuseppe

    2018-01-01

    Mapping allosteric sites is emerging as one of the central challenges in physiology, pathology, and pharmacology. Nuclear Magnetic Resonance (NMR) spectroscopy is ideally suited to map allosteric sites, given its ability to sense at atomic resolution the dynamics underlying allostery. Here, we focus specifically on the NMR CHEmical Shift Covariance Analysis (CHESCA), in which allosteric systems are interrogated through a targeted library of perturbations (e.g., mutations and/or analogs of the allosteric effector ligand). The atomic resolution readout for the response to such perturbation library is provided by NMR chemical shifts. These are then subject to statistical correlation and covariance analyses resulting in clusters of allosterically coupled residues that exhibit concerted responses to the common set of perturbations. This chapter provides a description of how each step in the CHESCA is implemented, starting from the selection of the perturbation library and ending with an overview of different clustering options.

  14. A biologists' perspective on amalgamating traditional environmental knowledge and resource management

    OpenAIRE

    A.W.L. Hawley; Sherry, E.E.; Johnson, C.J.

    2004-01-01

    Recent transitions in resource management and recognition of the role of First Nations in resource management have heightened the need for conciliation of these two different views of the world and the place of people in it (world view). Efforts to amalgamate these diverse perspectives in resource management are impeded by a legacy of cultural imperialism and difficulties in understanding and accommodating differences in world views, including the place of resource management in society, the ...

  15. Stochastic Simulation Service: Bridging the Gap between the Computational Expert and the Biologist.

    Directory of Open Access Journals (Sweden)

    Brian Drawert

    2016-12-01

    Full Text Available We present StochSS: Stochastic Simulation as a Service, an integrated development environment for modeling and simulation of both deterministic and discrete stochastic biochemical systems in up to three dimensions. An easy to use graphical user interface enables researchers to quickly develop and simulate a biological model on a desktop or laptop, which can then be expanded to incorporate increasing levels of complexity. StochSS features state-of-the-art simulation engines. As the demand for computational power increases, StochSS can seamlessly scale computing resources in the cloud. In addition, StochSS can be deployed as a multi-user software environment where collaborators share computational resources and exchange models via a public model repository. We demonstrate the capabilities and ease of use of StochSS with an example of model development and simulation at increasing levels of complexity.

  16. Marine Mammal Necropsy: An Introductory Guide for Stranding Responders and Field Biologists

    Science.gov (United States)

    2007-09-01

    increasing friction we have found that the easiest to hardest surfaces are as follows: wet slab rock such as basalt , cobble, slick mud, gravel, sand...Flagging tape, biodegradable Laundry tags- www.golps.com,Daily Delivery Tag, 1-Ply fiber ; Label tape- www.VWR.com Tyveck tags-www.LSS.com; Blank tags

  17. Sustainable Development: Ten Arguments Against a Biologistic "Slow-Down" Philosophy of Social and Economic Development

    OpenAIRE

    Heilig, G.K.

    1997-01-01

    This paper is a provocative collection of arguments that came to the author's mind when reading through some of the literature on sustainable development. Similar to rather general sociological theories, these sustainability concepts - which are rooted in biological observations and theories of non-human biosphere - describe elements of a universal development philosophy. But they fail to take into account some of the most basic characteristics of how human societies and economics function a...

  18. A cross-sectional study to compare intraocular pressure measurement by sequential use of Goldman applanation tonometry, dynamic contour tonometry, ocular response analyzer, and Corvis ST

    Directory of Open Access Journals (Sweden)

    Sushma Tejwani

    2015-01-01

    Full Text Available Objective: To study the correlation and effect of sequential measurement of intraocular pressure (IOP with Goldmann applanation tonometer (GAT, ocular response analyzer (ORA, dynamic contour tonometer (DCT, and Corvis ST. Setting and Design: Observational cross-sectional series from the comprehensive clinic of a tertiary eye care center seen during December 2012. Methods: One hundred and twenty-five study eyes of 125 patients with normal IOP and biomechanical properties underwent IOP measurement on GAT, DCT, ORA, and Corvis ST; in four different sequences. Patients with high refractive errors, recent surgeries, glaucoma, and corneal disorders were excluded so as to rule out patients with evident altered corneal biomechanics. Statistical Analysis: Linear regression and Bland-Altman using MedCalc software. Results: Multivariate analysis of variance with repeated measures showed no influence of sequence of device use on IOP (P = 0.85. Linear regression r 2 between GAT and Corvis ST, Corvis ST and Goldmann-correlated IOP (IOPg, and DCT and Corvis ST were 0.37 (P = 0.675, 0.63 (P = 0.607, and 0.19 (P = 0.708, respectively. The Bland-Altman agreement of Corvis ST with GAT, corneal compensated IOP, and IOPg was 2 mmHg (−5.0 to + 10.3, −0.5 mmHg (−8.1 to 7.1, and 0.5 mmHg (−6.2 to 7.1, respectively. Intraclass correlation coefficient for repeatability ranged from 0.81 to 0.96. Conclusions: Correlation between Corvis ST and ORA was found to be good and not so with GAT. However, agreement between the devices was statistically insignificant, and no influence of sequence was observed.

  19. The Art of Political Murder de Francisco Goldman y el policial de no-ficción entre Estados Unidos y Guatemala

    Directory of Open Access Journals (Sweden)

    Andrea Pezzé

    2016-05-01

    Full Text Available This essay analyses the use of crime fiction in Francisco Goldman’s reportage The Art of Political Murder, and the contribution this makes to political change in the recent history of Guatemala. The aim of Goldman’s investigative report was not just to find a murderer, but above all to criticize the abuses of power perpetrated with impunity by the ‘State’, and the practices put in place to eradicate dissidence. To understand how the features of detective fiction are used in journalism to support the search for truth, the essay examines the social power of different typologies of Crime Novel. Goldman’s The Art of Political Murder is read from the viewpoint of literary Testimonio, against the Guatemalan and Central-American literary background, to see how it can contribute to the current struggle for identity.

  20. A Biologist's Musing on Teaching about Entropy and Energy: Towards a Better Understanding of Life Processes

    Science.gov (United States)

    Kattmann, Ulrich

    2018-01-01

    Should entropy and energy be emphasised as relevant concepts for biology education? This question will be discussed, highlighting the ways in which the concepts of entropy and energy can contribute to a better understanding of biological processes. Organisms are open systems. Therefore, the chosen perspective is different from the traditional…

  1. Using Physical and Computer Simulations of Collective Behaviour as an Introduction to Modelling Concepts for Applied Biologists

    Science.gov (United States)

    Rands, Sean A.

    2012-01-01

    Models are an important tool in science: not only do they act as a convenient device for describing a system or problem, but they also act as a conceptual tool for framing and exploring hypotheses. Models, and in particular computer simulations, are also an important education tool for training scientists, but it is difficult to teach students the…

  2. Biocompatibility and anti-microbiological activity characterization of novel coatings for dental implants: A primer for non-biologists

    Directory of Open Access Journals (Sweden)

    Thomas K Monsees

    2016-08-01

    Full Text Available With regard to biocompatibility, the cardinal requirement for dental implants and other medical devices that are in long-term contact with tissue is that the material does not cause any adverse effect to the patient. To warrant stability and function of the implant, proper osseointegration is a further prerequisite. Cells interact with the implant surface as the interface between bulk material and biological tissue. Whereas structuring, deposition of a thin film or other modifications of the surface are crucial parameters in determining favorable adhesion of cells, corrosion of metal surfaces and release of ions can affect cell viability. Both parameters are usually tested using in vitro cytotoxicity and adhesion assays with bone or fibroblasts cells. For bioactive surface modifications, further tests should be considered for biocompatibility evaluation. Depending on the type of modification, this may include analysis of specific cell functions or the determination of antimicrobial activities. The latter is of special importance as bacteria and yeast present in the oral cavity can be introduced during the implantation process and this may lead to chronic infections and implant failure. An antimicrobial coating of the implant is a way to avoid that. This review describes the essential biocompatibility assays for evaluation of new implant materials required by ISO 10993 and also gives an overview on recent test methods for specific coatings of dental implants.

  3. Biocompatibility and anti-microbiological activity characterization of novel coatings for dental implants: A primer for non-biologists

    Science.gov (United States)

    Monsees, Thomas

    2016-08-01

    With regard to biocompatibility, the cardinal requirement for dental implants and other medical devices that are in long-term contact with tissue is that the material does not cause any adverse effect to the patient. To warrant stability and function of the implant, proper osseointegration is a further prerequisite. Cells interact with the implant surface as the interface between bulk material and biological tissue. Whereas structuring, deposition of a thin film or other modifications of the surface are crucial parameters in determining favorable adhesion of cells, corrosion of metal surfaces and release of ions can affect cell viability. Both parameters are usually tested using in vitro cytotoxicity and adhesion assays with bone or fibroblasts cells. For bioactive surface modifications, further tests should be considered for biocompatibility evaluation. Depending on the type of modification, this may include analysis of specific cell functions or the determination of antimicrobial activities. The latter is of special importance as bacteria and yeast present in the oral cavity can be introduced during the implantation process and this may lead to chronic infections and implant failure. An antimicrobial coating of the implant is a way to avoid that. This review describes the essential biocompatibility assays for evaluation of new implant materials required by ISO 10993 and also gives an overview on recent test methods for specific coatings of dental implants.

  4. Biologist Edwin Grant Conklin and the idea of the religious direction of human evolution in the early 1920s.

    Science.gov (United States)

    Pavuk, Alexander

    2017-01-01

    Edwin Grant Conklin, renowned US embryologist and evolutionary popularizer, publicly advocated a social vision of evolution that intertwined science and modernist Protestant theology in the early 1920s. The moral prestige of professional science in American culture - along with Conklin's own elite scientific status - diverted attention from the frequency with which his work crossed boundaries between natural science, religion and philosophy. Writing for broad audiences, Conklin was one of the most significant of the religious and modernist biological scientists whose rhetoric went well beyond simply claiming that certain kinds of religion were amenable to evolutionary science; he instead incorporated religion itself into evolution's broadest workings. A sampling of Conklin's widely-resonant discourse suggests that there was substantially more to the religion-evolution story in the 1920s US than many creationist-centred narratives of the era imply.

  5. Would Virchow be a systems biologist? A discourse on the philosophy of science with implications for pathological research.

    Science.gov (United States)

    Stenzinger, Albrecht; Klauschen, Frederick; Wittschieber, Daniel; Weichert, Wilko; Denkert, Carsten; Dietel, Manfred; Roller, Claudio

    2010-06-01

    Research in pathology spans from merely descriptive work to functional studies, "-omics" approaches and, more recently, systems biology. The work presented here aims at placing pathological research into an epistemological context. Aided by Rudolf Virchow, we give an overview on the philosophy of science including the Wiener Kreis, Popper, Kuhn, Fleck and Rheinberger and demonstrate their implications for routine diagnostics and science in pathology. A focus is on the fields of "-omics" and systems pathology.

  6. 77 FR 59423 - Self-Regulatory Organizations; NYSE MKT LLC; Order Granting Approval of a Proposed Rule Change...

    Science.gov (United States)

    2012-09-27

    ... America Strategic Investments Corporation (``BAML''), Barclays Electronic Commerce Holdings Inc...''), Goldman, Sachs & Co. (``Goldman Sachs''), Datek Online Management Corp. (``TD Ameritrade'') and UBS...

  7. Peripheral neuropathy

    Science.gov (United States)

    ... peripheral; Neuritis - peripheral; Nerve disease; Polyneuropathy; Chronic pain - peripheral neuropathy ... Philadelphia, PA: Elsevier; 2016:chap 107. Shy ME. Peripheral neuropathies. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  8. [Computation of the K+, Na+ and Cl- fluxes through plasma membrane of animal cell with Na+/K+ pump, NKCC, NC cotransporters, and ionic channels with and without non-Goldman rectification in K+ channels. Norma and apoptosis].

    Science.gov (United States)

    Rubashkin, A A; Iurinskaia, V E; Vereninov, A A

    2010-01-01

    The balance of K+, Na+ and Cl- fluxes through cell membrane with the Na+/K+ pump, ion channels and NKCC and NC cotransporters is considered. It is shown that all unidirectional K+, Na+ and Cl- fluxes through cell membrane, permeability coefficients of ion channels and membrane potential can be computed for balanced ion distribution between cell and the medium if K+, Na+ and Cl- concentration in cell water and three fluxes are known: total Cl- flux, total K+ influx and ouabain-inhibitable "pump" component of the K+ influx. Changes in the mortovalent ion balance in lymphoid cells U937 induced to apoptosis by 1 microM staurosporine are analyzed as an example. It is found that the apoptotic shift in ion and water balance in studied cells is caused by a decrease in the pump activity which is accompanied by a decrease in the integral permeability of Na+ channels without significant increase in K+ and Cl- channel permeabilities. Computation shows that only a small part of the total fluxes of K+, Na+ and Cl- accounts for the fluxes via NKCC and NC cotransporters. Therefore, cotransport fluxes can not be studied using inhibitors.

  9. Clinical estimation of intraocular pressure with a non-contact tonometer and Goldman applanation tonometer as a tool for mass screening and its correlation with central corneal thickness: A comparative hospital based study

    Directory of Open Access Journals (Sweden)

    Anshulee Sood

    2015-01-01

    Full Text Available Purpose To assess the mean difference between intra-ocular pressure measurement by Goldmann applanation tonometer and Non Contact tonometer to determine the suitability of tonometer for community or mass screening and the variation in intra-ocular pressure between the two devices with respect to CCT. Material and Methods The proposed study was conducted on 300 eyes of 150 patients. The IOP assessment with the Goldmann applanation tonometer was always subsequent to that with the air-puff noncontact tonometer (AT-555. An average of three readings taken 15 seconds apart, with each method was taken to get final intraocular pressure reading for each eye. The central corneal thickness (CCT measurements were performed using the pachymeter. Results Majority of the eyes were found to be in the 12-24 mmHg group i.e. 51 % eyes in the right eye and 64 % in the left eye. 3. Mean IOP measured with NCT was 22.30±10.149 mmHg and with GAT was 18.31±7.427 mmHg, thus showing a difference of 3.99 mmHg. In patients where IOP was 24mm Hg the difference in the mean IOP for right eye was 5.69mmHg and for left eye 7.84mmHg (p<0.001. Both the methods of IOP measurement showed positive correlation with central corneal thickness. The NCT was more influenced by CCT than GAT; for every 10 micron CCT change, the IOP change expected with NCT was 0.47 mmHg and GAT was 0.29 mmHg. Conclusion Thus we can conclude that NCT can be used as a screening procedure in tertiary care centres catering to a large number of patients wherein it is not possible to do Goldmann applanation tonometry on all patients.. However, intraocular pressure readings may require adjustment, especially when measured with NCT in those patients who have a CCT that is significantly different from population mean.

  10. Microorganisms and insects, the enemies of the past. Biologists, physicists, chemists, historians and geologists are fighting against the bio deterioration of the historical heritage

    International Nuclear Information System (INIS)

    Almera, P.

    2015-01-01

    To continue enjoying trees and ancient property cultural is necessary to preserve them in good condition. With the passage of time, its backers - paper, parchment, wood or canvas - can be bio deterioration by your own composition or the environmental conditions to the they are subject. The damage could become irreparable. for this reason, specialists of all kinds of branches they combine knowledge and research to give with the formulas capable of alleviating alterations to properties chemical and mechanical provoked by the action of biological organisms over these materials. (Author)

  11. O papel do biólogo no gerenciamento do perigo aviário em aeroportos = The role of biologist in airport bird hazard management

    Directory of Open Access Journals (Sweden)

    Bezerra, George Christian Linhares

    2011-01-01

    Full Text Available A segurança operacional da aviação demanda o gerenciamento do perigo aviário. A maior parte dos eventos de colisão entre aves e aeronaves ocorre nas proximidades dos aeroportos, o que está relacionado à menor altitude de voo e concentração de aves devido a fatores atrativos. O artigo foca o papel do profissional de ciências biológicas no processo de gerenciamento do perigo aviário em aeroportos, tendo como objetivo descrever as atividades por ele executadas. A pesquisa consistiu de revisão da literatura, identificação da regulamentação aplicável e as práticas adotadas e, através de estudo de caso realizado em aeroporto localizado na região amazônica, foi possível coletar informações de interesse para a pesquisa. Os resultados apontam que o biólogo atua especificamente na identificação do perigo, identificando focos de atração de aves, espécies presentes e hábitos de comportamento. Além disso, assessora a avaliação de risco com informações sobre a probabilidade da ocorrência de colisões e sobre a gravidade das suas consequências

  12. Human radiation studies: Remembering the early years: Oral history of cell biologist Don Francis Petersen, Ph.D., conducted November 29, 1994

    International Nuclear Information System (INIS)

    1995-08-01

    This report is a transcript of an interview of Dr. Don Francis Petersen by representatives of the US DOE Office of Human Radiation Experiments. Dr. Petersen was selected for this interview because of his long research career at Los Alamos and his knowledge of the Atomic Energy Commission's biomedical program. Dr. Petersen did not personally conduct research on human subjects. After a brief biographical sketch Dr. Petersen discusses his remembrances of the early use of radionuclides as biological tracers, aspects of nuclear weapons testing in the 1940's and 1950's including fallout studies, the means by which research projects were approved, use of humans in the whole-body counter, and the Health Division Biomedical responsibilities

  13. Human radiation studies: Remembering the early years: Oral history of cell biologist Don Francis Petersen, Ph.D., conducted November 29, 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-08-01

    This report is a transcript of an interview of Dr. Don Francis Petersen by representatives of the US DOE Office of Human Radiation Experiments. Dr. Petersen was selected for this interview because of his long research career at Los Alamos and his knowledge of the Atomic Energy Commission`s biomedical program. Dr. Petersen did not personally conduct research on human subjects. After a brief biographical sketch Dr. Petersen discusses his remembrances of the early use of radionuclides as biological tracers, aspects of nuclear weapons testing in the 1940`s and 1950`s including fallout studies, the means by which research projects were approved, use of humans in the whole-body counter, and the Health Division Biomedical responsibilities.

  14. 'Spanish' flu and army horses : What historians and biologists can learn from a history of animals with flu during the 1918-1919 influenza pandemic

    NARCIS (Netherlands)

    Haalboom, Floor

    2014-01-01

    At the time of the 1918-1919 ‘Spanish' influenza pandemic, influenza researchers did not just relate this disease to the human population, despite the focus of historians of medicine on its human aspects and meanings. In line with the use of historical reports of animals with influenza in

  15. [Uued heliplaadid] / Siim Nestor

    Index Scriptorium Estoniae

    Nestor, Siim, 1974-

    1999-01-01

    Heliplaatide tutvustus : Jamiroquai "Synkronized", Brandi Ifgray "Stargazer", Natalie Cole "Snowfall On the Sahara", Pizzicato Five "Playboy Playgirl", Erinevad esitajad "Marvin is 60 - A Tribute Album"

  16. Enteral nutrition - child - managing problems

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/patientinstructions/000164.htm Enteral nutrition - child - managing problems To use the sharing features ... trouble breathing, call 911. References Mcclave SA. Enteral nutrition. In: Goldman L, Schafer AI, eds. Goldman-Cecil ...

  17. 77 FR 47138 - Self-Regulatory Organizations; NYSE MKT LLC; Notice of Filing of Proposed Rule Change Amending...

    Science.gov (United States)

    2012-08-07

    ..., NYSE Euronext, Banc of America Strategic Investments Corporation (``BAML''), Barclays Electronic Commerce Holdings Inc. (``Barclays''), Citadel Securities LLC (``Citadel''), Citigroup Financial Strategies, Inc. (``Citigroup''), Goldman, Sachs & Co. (``Goldman Sachs''), Datek Online Management Corp. (``TD...

  18. Hyperparathyroidism

    Science.gov (United States)

    ... LJ, de Kretser DM, et al, eds. Endocrinology: Adult and Pediatric . 7th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 63. Thakker RV. The parathyroid glands, hypercalcemia and hypocalcemia. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  19. Parathyroid hyperplasia

    Science.gov (United States)

    ... LJ, de Kretser DM, et al, eds. Endocrinology: Adult and Pediatric . 7th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 63. Thakker R. The parathyroid glands, hypercalcemia and hypocalcemia. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  20. Parathyroid adenoma

    Science.gov (United States)

    ... LJ, de Kretser DM, et al, eds. Endocrinology: Adult and Pediatric . 7th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 63. Thakker RV. The parathyroid glands, hypercalcemia, and hypocalcemia. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  1. Osteitis fibrosa

    Science.gov (United States)

    ... LJ, de Kretser DM, et al, eds. Endocrinology: Adult and Pediatric . 7th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 63. Thakker RV. The parathyroid glands, hypercalcemia and hypocalcemia. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  2. Allergies - overview

    Science.gov (United States)

    ... used to treat food allergies because of the danger of a severe reaction. Allergy shots may need ... allergic or immunologic disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  3. Diarrhea - overview

    Science.gov (United States)

    ... What to do if you are breastfeeding What danger signs to watch out for Avoid medicines for ... with diarrhea and malabsorption. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  4. Hypovolemic shock

    Science.gov (United States)

    ... the person's position unless they are in immediate danger. Do not give fluids by mouth. If person ... the patient with shock. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  5. Burns

    Science.gov (United States)

    ... regularly. Teach children about fire safety and the danger of matches and fireworks. Keep children from climbing ... injuries of the lungs. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  6. Dementia

    Science.gov (United States)

    ... Poor judgment and loss of ability to recognize danger Using the wrong word, not pronouncing words correctly, ... disease and other dementias. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  7. MIBG scintiscan

    Science.gov (United States)

    ... done on pregnant women. The radiation can pose danger to the unborn baby. ... medulla, catecholamines, and pheochromocytoma. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  8. High potassium level

    Science.gov (United States)

    ... level is very high, or if you have danger signs, such as changes in an ECG . Emergency ... Seifter JL. Potassium disorders. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  9. Vascular dementia

    Science.gov (United States)

    ... poor judgment and loss of ability to recognize danger Using the wrong word, not pronouncing words correctly, ... disease and other dementias. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  10. Headaches - danger signs

    Science.gov (United States)

    Migraine headache - danger signs; Tension headache - danger signs; Cluster headache - danger signs; Vascular headache - danger signs ... and other head pain. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  11. Dementia due to metabolic causes

    Science.gov (United States)

    ... Poor judgment and losing the ability to recognize danger Using the wrong word, not pronouncing words correctly, ... disease and other dementias. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  12. Pulmonary valve stenosis

    Science.gov (United States)

    ... surgery - discharge Images Heart valves References Carabello BA. Valvular heart disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil ... Saunders; 2016:chap 69. Otto CM, Bownow RO. Valvular heart disease. In: Mann DL, Zipes DP, Libby P, Bonow ...

  13. Tricuspid regurgitation

    Science.gov (United States)

    ... and dentist if you have a history of heart valve disease or congenital heart disease before treatment. Some people ... Regurgitation Tricuspid Regurgitation Ebstein's anomaly References Carabello BA. Valvular heart disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  14. Mitral valve regurgitation

    Science.gov (United States)

    ... and dentist if you have a history of heart valve disease or congenital heart disease before treatment. Some people ... the middle Heart, front view References Carabello BA. Valvular heart disease. In: Goldman L, Schafer AI, eds. Goldman-Cecil ...

  15. Aortic stenosis

    Science.gov (United States)

    ... Images Aortic stenosis Heart valves References Carabello BA. Valvular heart disease. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/ ...

  16. Epilepsy - overview

    Science.gov (United States)

    ... or antiepileptic drugs), may reduce the number of future seizures: These drugs are taken by mouth. Which ... 23986299 . Wiebe S. The epilepsies. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  17. Deciding about treatments that prolong life

    Science.gov (United States)

    ... you are receiving or may need in the future. Learn about the treatments and how they would ... patients and their families. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  18. Intracardiac electrophysiology study (EPS)

    Science.gov (United States)

    ... rhythm Determine whether you are at risk for future heart events, especially sudden cardiac death See if ... patient with suspected arrhythmia. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  19. Alzheimer disease

    Science.gov (United States)

    ... likely need to plan for their loved one's future care. The final phase of the disease may ... disease and other dementias. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  20. Do-not-resuscitate order

    Science.gov (United States)

    ... medical condition and what to expect in the future. Talk to your doctor about the pros and ... patients and their families. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  1. Cytomegalovirus (CMV) infection

    Science.gov (United States)

    ... If your immune system becomes weakened in the future, this virus may have the chance to reactivate, ... 140. Drew WL. Cytomegalovirus. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  2. Tendinitis

    Science.gov (United States)

    ... ability to function properly, improve healing, and prevent future injury. In rare cases, surgery is needed to ... disorders and sports medicine. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  3. Mallory-Weiss tear

    Science.gov (United States)

    ... the liver and problems with blood clotting make future bleeding episodes more likely to occur. ... Jensen DM. Gastrointestinal hemorrhage. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  4. Duchenne muscular dystrophy

    Science.gov (United States)

    ... and gene therapy may be used in the future. The use of steroids and the lack of ... Selcen D. Muscle diseases. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  5. Anti-reflux surgery

    Science.gov (United States)

    ... surgery. You may need another surgery in the future if you develop new reflux symptoms or swallowing ... Diseases of the esophagus. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  6. Post-traumatic stress disorder

    Science.gov (United States)

    ... of the event Feeling like you have no future 3. Hyperarousal Always scanning your surroundings for signs ... disorders in medical practice. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  7. Angiodysplasia of the colon

    Science.gov (United States)

    ... are likely to have more bleeding in the future. The outlook remains good if the bleeding is ... of the gastrointestinal tract. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 25th ed. Philadelphia, PA: ...

  8. Dealing with chronic cancer

    Science.gov (United States)

    ... enjoying the present instead of worrying about the future. Focus on the small things that bring you ... E. The chronic leukemias. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  9. Sydenham chorea

    Science.gov (United States)

    ... The provider may also prescribe antibiotics to prevent future RF infections. This is called preventive antibiotics, or ... AE. Other movement disorders. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  10. Preeclampsia

    Science.gov (United States)

    ... preeclampsia makes a woman a higher risk for future problems such as: Heart disease Diabetes Kidney disease ... medical problems in pregnancy. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  11. Bursitis

    Science.gov (United States)

    ... be ordered include: Removing fluid from the bursa Culture of the fluid Ultrasound MRI Treatment Your provider ... JJ. Bursitis, tendinitis, and other periarticular disorders of sports medicine. In: Goldman L, Schafer AI, eds. Goldman- ...

  12. Aging changes in the breast

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/003999.htm Aging changes in the breast To use the sharing ... chap 198. Walston JD. Common clinical sequelae of aging. In: Goldman L, Schafer AI, eds. Goldman-Cecil ...

  13. Gastrointestinal bleeding

    Science.gov (United States)

    ... Sigmoidoscopy Alternative Names Lower GI bleeding; GI bleeding; Upper GI bleeding; Hematochezia Images GI bleeding - series Fecal occult blood test References Kovacs TO, Jensen DM. Gastrointestinal hemorrhage. In: Goldman L, Schafer AI, eds. Goldman- ...

  14. Taking medicines to treat tuberculosis

    Science.gov (United States)

    Tuberculosis - medicines; DOT; Directly observed therapy; TB - medicines ... Ellner JJ. Tuberculosis. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 324. ...

  15. Anaerobic bacteria

    Science.gov (United States)

    Anaerobic bacteria are bacteria that do not live or grow when oxygen is present. In humans, these bacteria ... Brook I. Diseases caused by non-spore-forming anaerobic bacteria. In: Goldman L, Schafer AI, eds. Goldman-Cecil ...

  16. Apolipoprotein CII

    Science.gov (United States)

    ... lipoprotein ( VLDL ), which is made up of mostly triglycerides (a type of fat in your blood). This ... gov/pubmed/23257303 . Semenkovich CF. Disorders of lipid metabolism. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  17. 78 FR 73586 - Senior Executive Service Performance Review Board (PRB) and Executive Resources Board (ERB...

    Science.gov (United States)

    2013-12-06

    ...: Performance Review Board Leland L. Gardner, Chairman Rachel D. Campbell, Member Craig M. Keats, Member Lucille Marvin, Alternate Member Executive Resources Board Rachel D. Campbell, Chairman Lucille Marvin, Member Joseph H. Dettmar, Alternate Member These changes to the PRB and ERB membership are due to the departure...

  18. Microorganisms and insects, the enemies of the past. Biologists, physicists, chemists, historians and geologists are fighting against the bio deterioration of the historical heritage; Biologos, Fisicos, Quimicos, Historiadores y Geologos luchan contra el biodeterioro del patrimonio historico

    Energy Technology Data Exchange (ETDEWEB)

    Almera, P.

    2015-07-01

    To continue enjoying trees and ancient property cultural is necessary to preserve them in good condition. With the passage of time, its backers - paper, parchment, wood or canvas - can be bio deterioration by your own composition or the environmental conditions to the they are subject. The damage could become irreparable. for this reason, specialists of all kinds of branches they combine knowledge and research to give with the formulas capable of alleviating alterations to properties chemical and mechanical provoked by the action of biological organisms over these materials. (Author)

  19. 78 FR 23963 - Self-Regulatory Organizations; NYSE MKT LLC; Notice of Filing and Immediate Effectiveness of...

    Science.gov (United States)

    2013-04-23

    ... Strategic Investments Corporation (``BAML''), Barclays Electronic Commerce Holdings Inc. (``Barclays... & Co. (``Goldman Sachs''), Datek Online Management Corp. (``TD Ameritrade'') and UBS Americas Inc...

  20. Pop / Erik Morna

    Index Scriptorium Estoniae

    Morna, Erik, 1969-

    2003-01-01

    Heliplaatidest: Marvin Gaye"What's Going On", Dynamite Vikings featuring Pierre Dorge "Vikingology", Pet Shop Boys "Disco 3", erinevad esitajad "We're a Happy Family: A Tribute to the Ramones", Ozzy Osbourne "Essential"

  1. Sobre el impacto de las telecomunicaciones en las ciudades

    OpenAIRE

    Sánchez de Madariaga, Inés

    2011-01-01

    Resumen de los libros publicados en 1996 "Telecommunications and the city: electronic spaces, urban places" de Stephen Graham y Simon Marvin, y "CyberCities: visual perception in the age of electronic communication" de M. Christine Boyer.

  2. 77 FR 74273 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-12-13

    ... (SD) Terry L. Anderson (PA) Sammy J. Barada (NE) Timothy Bradford (TN) Cody W. Cook (OK) Marvin R...) Thomas L. Oglesby (GA) Garrick Pitts (AR) Jonathan C. Rollings (IA) Preston S. Salisbury (MT) Victor M...

  3. Counterfeit Parts Prevention Strategies Guide

    Science.gov (United States)

    2014-06-24

    requirements of 252.211-7003, Item Unique Identification and Valuation .” This section establishes a recommended approach for requirements, polices, and...7003 Item Unique Identification and Valuation DoDI 4140.67 DoD Counterfeit Prevention Policy DoDI 5200.39 Critical Program Information (CPI...Deborah Valley deborah.valley@ll.mit.edu MIT Fred Van Milligen fvanmilligen@jdsu.com JDSU Marvin VanderWeg marvin.vanderwag@spacex.c om SpaceX Gerrit

  4. Beyond Words: Phonological Short-Term Memory and Syntactic Impairment in Specific Language Impairment

    Science.gov (United States)

    Bishop, Dorothy V. M.

    2006-01-01

    The assessment of nonword repetition in children goes back at least to 1974, when the Goldman-Fristoe-Woodcock Auditory Skills Battery was published, including a subtest (Sound Mimicry) assessing nonword repetition (Goldman, Fristoe, & Woodcock, 1974). Nevertheless, it was not until 20 years later, when Gathercole and Baddeley (1990) reported a…

  5. Aortic insufficiency

    Science.gov (United States)

    ... page, please enable JavaScript. Aortic insufficiency is a heart valve disease in which the aortic valve does not close ... aortic insufficiency Images Aortic insufficiency References Carabello BA. Valvular heart disease. In: Goldman L, Schafer AI, eds. Goldman-Cecil ...

  6. Preventing infections when visiting

    Science.gov (United States)

    ... need.) When you visit a patient in the hospital, keep your hands away from your face. Cough or sneeze into a tissue or into the crease of your elbow, not into the air. References Calfee DP. Prevention and control of health care-associated infections. In: Goldman L, Schafer AI, eds. Goldman-Cecil ...

  7. Catheter-associated UTI

    Science.gov (United States)

    ... UTI; Health care-associated UTI; Catheter-associated bacteriuria; Hospital acquired-UTI Images Bladder catheterization, female Bladder catheterization, male References Calfee DP. Prevention and control of health care-associated infections. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  8. 78 FR 41797 - Granting of Request for Early Termination of the Waiting Period Under the Premerger Notification...

    Science.gov (United States)

    2013-07-11

    ....; Virgin Group Holdings Limited; Delta Airlines, Inc. 20130889 G Centre Capital Investors V, L.P.; Overhill....; Vista Equity Partners Fund IV, L.P. 20130906 G The Goldman Sachs Group, Inc.; APT Software Holdings, Inc.; The Goldman Sachs Group, Inc. 20130908 G MABEG/Verein zur Fordurung und Beratung der MAHLE Gruppe e.V...

  9. The challenge of wolf recovery: an ongoing dilemma for state managers

    Science.gov (United States)

    Mech, L. David

    2013-01-01

    “Dave, would you do another legal declaration on the wolf for us?” The weary voice on the phone belonged to Mike Jimenez, Northern Rocky Mountain Wolf Management and Science Coordinator for the U.S. Fish and Wildlife Service (FWS). He was calling from Wyoming to ask me to prepare a document to address a legal challenge to the FWS’s August 2012 delisting of the wolf (Canis lupus) in Wyoming, a highly controversial move. Mike’s tone reflected the reality that — as so many wildlife biologists know and live each day — wildlife management is mainly people management. This contention could not be truer for managing any wildlife species than for managing the wolf. Dubbed “the beast of waste and desolation” by Teddy Roosevelt (The Wilderness Hunter 1893/1900), wolves had been universally hated as prolific predators of valuable livestock and game. Around the turn of the 20th century, members of the U.S. Biological Survey and various state agents, ranchers, cowboys, and other frontiersmen poisoned and persecuted wolves, extirpating them from most of the contiguous United States (Young and Goldman 1944). By 1967, Minnesota and nearby Isle Royale National Park in Michigan held the only remaining wolves in the Lower 48 states, prompting the FWS to place the wolf on the Endangered Species List (established by the Endangered Species Preservation Act of 1966). The wolf then became the list’s poster species, and the timing was ideal: Silent Spring (Carson 1962) had just seeded and fertilized the environmental movement, which blossomed on Earth Day (April 22, 1970) into the environmental revolution. “Save the wolf!” became one of the movement’s rallying cries. And save the wolf we did.

  10. Fifty challenging problems in probability with solutions

    CERN Document Server

    Mosteller, Frederick

    1987-01-01

    Can you solve the problem of ""The Unfair Subway""? Marvin gets off work at random times between 3 and 5 p.m. His mother lives uptown, his girlfriend downtown. He takes the first subway that comes in either direction and eats dinner with the one he is delivered to. His mother complains that he never comes to see her, but he says she has a 50-50 chance. He has had dinner with her twice in the last 20 working days. Explain. Marvin's adventures in probability are one of the fifty intriguing puzzles that illustrate both elementary ad advanced aspects of probability, each problem designed to chall

  11. Aspiration pneumonia

    Science.gov (United States)

    ... Images Pneumococci organism Bronchoscopy Lungs Respiratory system References Musher DM. Overview of pneumonia. In: Goldman L, Schafer ... University of Pennsylvania, Philadelphia, PA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial ...

  12. Injury - kidney and ureter

    Science.gov (United States)

    ... kidney; Ureteral injury; Pre-renal failure - injury, Post-renal failure - injury; Kidney obstruction - injury Images Kidney anatomy Kidney - blood and urine flow References Molitoris BA. Acute kidney injury. In: Goldman ...

  13. Lithotripsy

    Science.gov (United States)

    ... ultrasound, will pass through your body until they hit the kidney stones. If you are awake, you ... Bushinsky DA. Nephrolithiasis In: Goldman L, Schafer AI, eds. ... BR, Krambeck AE, Lingeman JE. Surgical management of upper ...

  14. Arrhythmias

    Science.gov (United States)

    ... sign of other heart problems, or an immediate danger to your health. ... patient with suspected arrhythmia. In: Goldman L, Schafer AI, eds. Goldman’s Cecil Medicine . 25th ed. Philadelphia, PA: ...

  15. Serum globulin electrophoresis

    Science.gov (United States)

    ... plasma proteins. In: Baynes JW, Dominiczak MH, eds. Medical Biochemistry . 4th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 4. Rajkumar SV. Plasma cell disorders. In: Goldman L, Schafer AI, ... . 25th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 187.

  16. Ferritin blood test

    Science.gov (United States)

    ... and minerals. In: Baynes JW, Dominiczak MH, eds. Medical Biochemistry . 4th ed. Elsevier Saunders; 2014:chap 11. Ginder GD. Microcytic and hypochromic anemias. In: Goldman L, Schafer AI, ... . 25th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 159.

  17. Vanameister avas rahalaeka / Silvia Viidik

    Index Scriptorium Estoniae

    Viidik, Silvia, 1972-

    2008-01-01

    Warren Buffett ulatas abikäe investeerimispangale Goldman Sachs, investeerides sinna 5 miljardit dollarit ning tõttas appi General Electricule, kuhu investeeris 3 miljardit dollarit. Vt. samas: Warren Buffett; Berkshire Hathaway

  18. Cholesterol and lifestyle

    Science.gov (United States)

    ... normal range. These healthy habits may help prevent future heart attacks and other health problems. Eat foods ... with health and disease. In: Goldman L, Schafer AI, eds. Goldman’s Cecil Medicine . 25th ed. Philadelphia, PA: ...

  19. (AJST) SOME ASPECTS OF WATER QUALITY CHARACTERISTICS ...

    African Journals Online (AJOL)

    SHALLOW TROPICAL MAN-MADE RESERVOIRS IN KENYA. Mwaura, F. Department .... oxygen controls certain biogeochemical processes like the nitrogen cycle .... deep ASUs (Brower and Zar, 1977; Goldman and Horne 1983). RESULTS.

  20. Daily bowel care program

    Science.gov (United States)

    ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 136. Koyle MA, Lorenzo AJ. ... eds. Campbell-Walsh Urology . 11th ed. Philadelphia, PA: Elsevier; 2016:chap 144. Lembo AJ. Constipation. In: Feldman ...

  1. Smear of duodenal fluid aspirate

    Science.gov (United States)

    ... Management by Laboratory Methods . 23rd ed. Philadelphia, PA: Elsevier; 2017:chap 64. Dupont HL. Approach to the ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 283. Fritsche TR, Pritt BS. ...

  2. Hemolysis

    Science.gov (United States)

    ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 161. Gallagher PG. Red blood ... Basic Principles and Practice . 6th ed. Philadelphia, PA: Elsevier; 2013:chap 43. Michel M. Autoimmune and intravascular ...

  3. Hepatitis

    Science.gov (United States)

    ... Gastrointestinal and Liver Disease. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 90. Pawlotsky J-M. Chronic ... eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 149. Sjogren MH, Bassett JT. ...

  4. Fecal smear

    Science.gov (United States)

    ... Management by Laboratory Methods . 23rd ed. Philadelphia, PA: Elsevier; 2017:chap 64. DuPont HL. Approach to the ... AI, eds. Goldman's Cecil Medicine . 25thed. Philadelphia, PA: Elsevier Saunders; 2016:chap 283. Haines CF, Sears CL. ...

  5. Arteriogram

    Science.gov (United States)

    ... eds. Rutherford's Vascular Surgery . 8th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 102. Goldstein LB. Approach to ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 406. Kern M. Catheterization and ...

  6. Fibromyalgia

    Science.gov (United States)

    ... eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 274. Mbuyi N. Fibromyalgia. In: ... FF, ed. Ferri's Clinical Advisor 2018 . Philadelphia, PA: Elsevier; 2017:491-492. Selfridge NJ. Fibromyalgia. In: Rakel ...

  7. Culture - colonic tissue

    Science.gov (United States)

    ... Management by Laboratory Methods . 23rd ed. Philadelphia, PA: Elsevier; 2017:chap 64. DuPont HL. Approach to the ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 283. Hall GS, Woods GL. ...

  8. Giardia infection

    Science.gov (United States)

    ... eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 283. Haines CF, Sears CL. ... Gastrointestinal and Liver Disease . 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 110. Nash TE, Hill DR. ...

  9. Hemoglobin derivatives

    Science.gov (United States)

    ... Basic Principles and Practice. 7th ed. Philadelphia, PA: Elsevier; 2017:chap 43. Bunn HF. Approach to the ... eds. Goldman-Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 158. Christiani DC. Physical and ...

  10. Shigellosis

    Science.gov (United States)

    ... Nelson Textbook of Pediatrics . 20th ed. Philadelphia, PA: Elsevier; 2016:chap 340. DuPont HL. Approach to the ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 283. Haines CF, Sears CL. ...

  11. Fecal culture

    Science.gov (United States)

    ... Management by Laboratory Methods . 23rd ed. Philadelphia, PA: Elsevier; 2017:chap 64. DuPont HL. Approach to the ... AI, eds. Goldman's Cecil Medicine . 25thed. Philadelphia, PA: Elsevier Saunders; 2016:chap 283. Haines CF, Sears CL. ...

  12. How Is Pain Managed?

    Science.gov (United States)

    ... Detection- Goggins Lab Sol Goldman Center Discussion Board Pain Management Pain is a very common symptom in patients ... of pain. Pain Assessment The first step in pain management is a thorough assessment. Your healthcare provider will ...

  13. Speech disorders - children

    Science.gov (United States)

    ... disorder; Voice disorders; Vocal disorders; Disfluency; Communication disorder - speech disorder; Speech disorder - stuttering ... evaluation tools that can help identify and diagnose speech disorders: Denver Articulation Screening Examination Goldman-Fristoe Test of ...

  14. What Is Walking Pneumonia?

    Science.gov (United States)

    ... different from regular pneumonia? Answers from Eric J. Olson, M.D. Walking pneumonia is an informal term ... be treated with an antibiotic. With Eric J. Olson, M.D. Goldman L, et al., eds. Mycoplasma ...

  15. Medical Device Plug-and-Play Interoperability Standards and Technology Leadership

    Science.gov (United States)

    2016-10-01

    death,” The Boston Globe, April 3 2010. 27. Arney D, Pajic M, Goldman JM, Lee I, Mangharam R, Sokolsky O, “Toward Patient Safety in Closed - Loop Medical ...becoming increasingly clear. We have been providing medical device interoperability domain expertise to assist the Veterans Administration in a...15. Wallroth C, Goldman J, Manigel J, Osborn D, Roellike T, Weininger S, Westenskow D, “Development of a Standard for Physiologic Closed Loop

  16. Minimally invasive aesthetic procedures in young adults

    OpenAIRE

    Wollina, Uwe; Goldman, Alberto

    2011-01-01

    Uwe Wollina1, Alberto Goldman21Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, Germany; 2Clinica Goldman, Porto Alegre, Rio Grande du Sul, BrazilAbstract: Age is a significant factor in modifying specific needs when it comes to medical aesthetic procedures. In this review we will focus on young adults in their third decade of life and review minimally invasive aesthetic procedures other than cosmetics and cosmeceuticals. Correction of asy...

  17. Wall Street som kreationistisk forkynder

    DEFF Research Database (Denmark)

    Ekman, Susanne

    2016-01-01

    Artiklen gennemgår Karen Hos etnografi om Wall Street: "Liquidated: An ethnography of Wall Street" set i lyset af den offentlige debat vedrørende Goldman Sachs opkøb af Dong......Artiklen gennemgår Karen Hos etnografi om Wall Street: "Liquidated: An ethnography of Wall Street" set i lyset af den offentlige debat vedrørende Goldman Sachs opkøb af Dong...

  18. Design and Testing of a Thermostable Platform for Multimerization of Single Domain Antibodies

    Science.gov (United States)

    2012-08-01

    H.J. Properties , production, and applications of camelid single domain antibody fragments. Appl. Microbiol. Biot. 2007, 77, 13‒22. 2. Goldman...Conway, J.; Sherwood, L.J.; Fech, M.; Vo, B.; Liu, J.L.; Hayhurst, A. Thermostable llama single domain antibodies for detection of Botulinum A...antiparallel coiled-coil inserted. J. Mol. Bio. 2001, 306, 25‒35. 9. Liu, J.L.; Anderson, G.P.; Goldman, E.R. Isolation of anti- toxin single domain

  19. Commentary

    Indian Academy of Sciences (India)

    Unknown

    the possible restoration of function across formerly severed spinal nerves. .... biologists, conservation biologists, and public health biologists. ... medicine”, we can expect the market to play a larger role in deciding which areas of science need.

  20. 78 FR 49420 - Parties Asked To Refresh the Record Regarding Property Records for Rate-of-Return Carriers

    Science.gov (United States)

    2013-08-14

    ... Competition Bureau, Pricing Policy Division, (202) 418-1520 or (202) 418-0484 (TTY), or via email Marvin.Sacks.... Sacks, Wireline Competition Bureau, Pricing Policy Division, at (202) 418-1520 or via email at [email protected] . Federal Communications Commission. Elizabeth McIntyre, Deputy Division Chief, Pricing...

  1. Empathic surroundings

    NARCIS (Netherlands)

    Mihelj, M.; van den Broek, Egon

    2008-01-01

    In his new book (2007), Marvin Minsky states that Artificial Intelligence (AI) needs empathy to become truly smart, as is illustrated through human-human interaction. The latter also holds for Virtual Reality (VR), where the interest increases to unravel the emotional state of users has to be

  2. Proceedings 2014: Selected Papers from the Eighteenth College-Wide Conference for Students in Languages, Linguistics & Literature (18th, Honolulu, Hawai'i, April 26, 2014)

    Science.gov (United States)

    Leal, Priscila, Ed.; West, Gordon, Ed.

    2015-01-01

    The theme for this year's annual graduate student conference of the College of Languages, Linguistics, and Literature (LLL) was "Your Voice, My Voice: Literature, Language, Culture and Society." Translation and interpretation guided the theme for the conference, with Dr. Marvin Puakea Nogelmeier of the Kawaihuelani Center for Hawaiian…

  3. Jane Austen: A Collection of Critical Essays. Twentieth Century Views Series.

    Science.gov (United States)

    Watt, Ian, Ed.

    One of a series of works aimed at presenting contemporary critical opinion on major authors, this collection includes essays by Virginia Woolf, C. S. Lewis, Edmund Wilson, Ian Watt, Alan D. McKillop, Reuben A. Brower, Marvin Mudrick, Mark Schorer, Arnold Kettle, Lionel Trilling, Kingsley Amis, Andrew H. Wright, Donald J. Greene, and D. W.…

  4. Investigations on a large collection of cosmic dust from the central Indian Ocean.

    Digital Repository Service at National Institute of Oceanography (India)

    Parashar, K.; ShyamPrasad, M.; Chauhan, S.S.S.

    of California, Los Angeles, 1983, pp. 152 T. Laevastu, O. Mellis, Trans. AGU 36, 385 (1955) S.G. Love, D.E. Brownlee, Science 262, 550 (1993) U.B. Marvin, M.T. Einaudi, Geochim. Cosmochim. Acta 31, 1871 (1967) M. Maurette, C. Hammer, D.E. Brownlee, N. Reeh, H...

  5. Symposium on the Nature of Science—Streaming Video Archive

    Science.gov (United States)

    Oddone – Welcome Mark Ratner – Nano 201: A Gentle Introduction to Nanotechnology and Nanoscience Marsha Physical Sciences Neil Kelleher – How a Chemist Needs Computer Science, Biology, and Engineering to Push – Incorporating Nanotechnology into the Curriculum (streamed session not available) Rich Marvin – Using

  6. Islam, Islamism, and Democratic Values. Footnotes. Volume 11, Number 4

    Science.gov (United States)

    Kuehner, Trudy

    2006-01-01

    On May 6-7, 2006 FPRI's Marvin Wachman Fund for International Education hosted 44 teachers from 16 states across the country for a weekend of discussion on teaching about Islam. Speakers were drawn from the disciplines of religious studies, anthropology, political science, history, law, and journalism. The institute, held in Bryn Mawr, Pa., was…

  7. Research on a Frame-Based Model of Reading Comprehension. Final Report.

    Science.gov (United States)

    Goldstein, Ira

    This report summarizes computational investigations of language comprehension based on Marvin Minsky's theory of frames, a recent advance in artifical intelligence theories about the representation of knowledge. The investigations discussed explored frame theory as a basis for text comprehension by implementing models of the theory and developing…

  8. Socialization, Social Cognitive Factors and the Sibling Relationship.

    Science.gov (United States)

    Howe, Nina

    Two separate studies suggest that the development of positive sibling relations may be related to siblings' social-cognitive skills (Stewart & Marvin, 1984) and the nature of mothers' conversations with their children (Dunn & Kendrick, 1982). The purpose of the present study was to provide a synthesis of these two studies and to demonstrate the…

  9. Combating Terrorism: Research Priorities in the Social, Behavioral and Economic Sciences

    Science.gov (United States)

    2006-02-10

    the psychological aspects of traumatic stress reactions to the many neurobio - logic systems activated under stress that allow individuals to assess...Agriculture Carl Shapiro U.S. Geological Survey Marc Shepanek NASA Joshua Sinai Department of Homeland Security Marvin Singer Department of Energy Neal

  10. Resonance – Journal of Science Education | Indian Academy of ...

    Indian Academy of Sciences (India)

    Keywords. Chemical synthesis of genes for yeast alanine tRNA and E. coli supressor tRNA; Khorana's philosophy on science. Author Affiliations. Marvin H Caruthers1. Department of Chemistry and Biochemistry, University of Colorado at Boulder, Boulder, Colorado 80309, USA.

  11. A Chinese Birth Cohort: Theoretical Implications

    Science.gov (United States)

    Friday, Paul C.; Ren, Xin; Weitekamp, Elmar; Kerner, Hans-Jurgen; Taylor, Terrance

    2005-01-01

    Research on delinquency has shown consistent results across Western industrialized countries. Few studies have been done in non-Western cultures. This study reports on the results of a birth cohort study in China, which was started by Marvin Wolfgang but never completed. The cohort, born in 1973, was traced through official and community files.…

  12. Estimation of sound pressure levels of voiced speech from skin vibration of the neck

    NARCIS (Netherlands)

    Svec, JG; Titze, IR; Popolo, PS

    How accurately can sound pressure levels (SPLs) of speech be estimated from skin vibration of the neck? Measurements using a small accelerometer were carried out in 27 subjects (10 males and 17 females) who read Rainbow and Marvin Williams passages in soft, comfortable, and loud voice, while skin

  13. Domestic Interiors, Decorative Objects and their Multiple Temporalities : The Case of the Dutch Modernist Novel

    NARCIS (Netherlands)

    Verstraeten, Pieter

    2015-01-01

    In reaction to Marvin Trachtenberg’s ideas about the atemporal and chronicidal nature of modernist architecture (2010), this article charts the temporal heterogeneity characteristic of the domestic interior as it is represented in the Dutch modernist novel in the interwar period. Although, on par

  14. 76 FR 22939 - 30-Day Notice of Proposed Information Collection: Form- DS-1950, Department of State Application...

    Science.gov (United States)

    2011-04-25

    ... information collection and supporting documents from Marvin E. Moore, Bureau of Human Resources, Recruitment... Request: Extension of a currently approved collection. Originating Office: Bureau of Human Resources, Office of Recruitment, Examination, Employment (HR/REE) Form Number: DS-1950. Respondents: U.S. Citizens...

  15. Career Opportunities for the Future. Fueling the Education Explosion: Proceedings of Conference 3 (Cleveland, Ohio, March 29-30, 1984).

    Science.gov (United States)

    Gardner, Mary, Ed.; Reed-Mundell, Charlene, Ed.

    These proceedings contain 12 presentations from a conference which focused on forecasts of jobs in the 1990s and into the 21st century. The keynote address (Marvin Cetron) shows the need for reform in the American education system with illustrations drawn from the economic and employment situations in foreign countries. He makes predictions of…

  16. SASSI, Total and Differential Elastic and Inelastic Neutron Cross-Sections by Hauser-Feshbach

    International Nuclear Information System (INIS)

    Benzi, V.; Fabbri, F.; Zuffi, L.

    2001-01-01

    1 - Nature of physical problem solved: Neutron total and differential elastic and inelastic cross-section evaluation by means of the statistical model of Hauser-Feshbach (1) as modified by D. Goldman (2) (3). The Goldman modification includes the effect of spin-orbit coupling on transmission coefficients. 2 - Method of solution: For numerical integration the Fox-Goodwins method is used. 3 - Restrictions on the complexity of the problem: Angular momentum I less than or equal to 50. Number of excited levels less than or equal to 30

  17. Emergency Operations Center ribbon cutting

    Science.gov (United States)

    2009-01-01

    Center Director Gene Goldman and special guests celebrate the opening of the site's new Emergency Operations Center on June 2. Participants included (l t r): Steven Cooper, deputy director of the National Weather Service Southern Region; Tom Luedtke, NASA associate administrator for institutions and management; Charles Scales, NASA associate deputy administrator; Mississippi Gov. Haley Barbour; Gene Goldman, director of Stennis Space Center; Jack Forsythe, NASA assistant administrator for the Office of Security and Program Protection; Dr. Richard Williams, NASA chief health and medical officer; and Weldon Starks, president of Starks Contracting Company Inc. of Biloxi.

  18. A connection between the strong and weak interactions

    International Nuclear Information System (INIS)

    Treiman, S.B.

    1989-01-01

    By studying weak scattering reactions (such as pion-nucleon scattering), the author and his colleague Marvin L Goldberger became renowned in the 1950s for work on dispersion relations. As a result of their collaboration a remarkable and unexpected connection was found between strong and weak interaction quantities. Agreement with experiment was good. Work by others found the same result, but via the partially conserved axial reactor current relation between the axial current divergence and the canonical pion field. (UK)

  19. Independent Panel Evaluation of Dry Sludge PISA Program

    International Nuclear Information System (INIS)

    Fondeur, F.F.

    1999-01-01

    Dr. Kirk Yeager and Mr. Marvin Banks from Energetic Material Research and Technology Center (EMRTC) evaluated the Savannah River Site (SRS) efforts in the Dry Sludge program. They evaluated four program areas: energetic material formation, stability, initiation, and propagation. The panel evaluation included a site visit (July 13, 1999 and July 14, 1999) as well as a review of various reports and presentations by researchers involved in the program

  20. Technology Transfer: A Think Tank Approach to Managing Innovation in the Public Sector

    Science.gov (United States)

    1985-01-01

    he does fer of technology to include willing- have extensive experience in working ness to perform, capability to perform with biological scientists...Cetron’s of plans, if you will. I am a consumer of Encounters with the Future, and John the material we read about external Naisbitt’s Megatrends . All of...Marvin. Encounters with the Future: A Forecast of Life into the 21st Century. (McGraw-Hill. New York. 1982) Naisbitt, John. Megatrends : New

  1. Analysis of a Partial MOX Core Design with Tritium Targets for Light Water Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Anistratov, Dmitriy Y. [Texas A & M Univ., College Station, TX (United States); Adams, Marvin L. [Texas A & M Univ., College Station, TX (United States)

    1998-04-19

    This report constitutes tangible and verifiable deliverable associated with the task To study the effects of using WG MOX fuel in tritium-producing LWR” of the subproject Water Reactor Options for Disposition of Plutonium. The principal investigators of this subproject are Naeem M. Abdurrahman of the University of Texas at Austin and Marvin L. Adams of Texas A&M University. This work was sponsored by the Amarillo National Resource Center for Plutonium.

  2. Another Long March: Lessons from the Post-Vietnam Rebuild of the Marine Corps, 1969 to 1989

    Science.gov (United States)

    2014-05-22

    to retool their modest pre-AVF advertising and recruiting system, now inadequate in attracting enough qualified volunteers, proved challenging...cohesion and morale as a fighting force. The risk paid large dividends, as the Marine Corps, assisted in no small part by a successful advertising ...accessed 18 March 2014). Pimlott, John and Stephen Badsey. The Gulf War Assessed. New York: Arms and Armour , 1992. Pokrant, Marvin. Desert Storm at Sea

  3. Sources of Career Dissatisfaction among Mid-Level Coast Guard Officers.

    Science.gov (United States)

    1983-06-01

    fulfillment than staff managers, with the largest line-staff differences occurring in the esteem and self -actualization need areas; (2) line and staff...of Industrial Psychology and Organizational Behavior, ed. Marvin Dunnette, Chicago: Rand McNally & Co., 1976. Maslow , Abraham H., Motivation and...Personality, New York: Harper and Row, Publishers, 1954. Maslow , Abraham H., "The Study of Man At His Best," Behavioral Science Concepts and

  4. Support for Astronaut's View of Mexican/ Central American Fires and on-Line Earth Observations Training Manual

    Science.gov (United States)

    Kaminski, Charles F., Jr.

    1999-01-01

    A small project to compile remote sensing and in-site data to review the processes leading to the May 1998 Mexican/Central American fires was undertaken. A web page based on this project was assembled. The second project initiated involved an interactive and on-line program that will replace the paper version of the Earth Observations Preflight Training Manual. Technical support was provided to Prof. Marvin Glasser as needed.

  5. Proceedings of the Annual Day of Scientific Lectures (17th), and Annual Meeting of the National Society of Black Physicists (13th), Held in Baton Rouge, LA on March 21-24, 1990

    Science.gov (United States)

    1990-12-01

    Metropolitian Coca Cola Boston Compact BW -Rf r rfz-rr" c .r fret[ 203 Tomorrow’s job’s will require more education Years of schooling Future needed...Morgan Pennsylvania State Universiiy SPONSORSHIPS Alabama A&M University Students acEulty Marvin Sykes Dr. M. C. George Steven Pearson Michael Henry...Ibraham Francis Nyandeh Gabriel Ndow Melody Mixon Scholarship students selected by Dr. Kennedy Reed Sponsorship students selected by Mr. Gerald Davis

  6. Legacy K/Ar and 40Ar/39Ar geochronologic data from the Alaska-Aleutian Range batholith of south-central Alaska

    Science.gov (United States)

    Koeneman, Lisa L.; Wilson, Frederic H.

    2018-04-06

    Sample descriptions and analytical data for more than 200 K/Ar and 40Ar/39Ar analyses from rocks of the Alaska-Aleutian Range batholith of south-central Alaska are reported here. Samples were collected over a period of 20 years by Bruce R. Reed and Marvin A. Lanphere (both U.S. Geological Survey) as part of their studies of the batholith.

  7. EN TORNO A LA ASIMETRÍA DE LOS GÉNEROS EN LA SOCIEDAD MAPUCHE DEL PERÍODO DE LA CONQUISTA HISPANA

    Directory of Open Access Journals (Sweden)

    FRANCIS GOICOVICH VIDELA

    2003-08-01

    Full Text Available The primacy of masculine gender in almost every domain of culture is an universal phenomenon: men and women participate in differentiated value systems which, according to Marvin Harris, are grounded in the exclusive practice of war by men. The mapuche society in the conquest days was not an exception, and the ideology behind their social practices determined an asymmetry between both genders. centrality of civil legislation for the consolidation of the new order in the continent

  8. 21st Century Military Operations in a Complex Electromagnetic Environment

    Science.gov (United States)

    2015-07-01

    Natalie Crawford RAND Corporation RDML Jon P. Cryer, USN (ret) Northrop Grumman Mr. Stephen Cummings Raytheon Dr. Eric Evans MIT Lincoln...Heyer U.S. Navy Ms. Leslie Litton U.S. Army Dr. Charles Perkins National Reconnaissance Office Mr. Marvin Potts U.S. Air Force Dr. Stephen ...Neil Fox Virginia Tech Applied Research Corporation Ms. Hannah Freeman Strategic Analysis, Inc. Mr. Marcus Hawkins Strategic Analysis, Inc. Dr

  9. Independent Panel Evaluation of Dry Sludge PISA Program

    Energy Technology Data Exchange (ETDEWEB)

    Fondeur, F.F.

    1999-10-20

    Dr. Kirk Yeager and Mr. Marvin Banks from Energetic Material Research and Technology Center (EMRTC) evaluated the Savannah River Site (SRS) efforts in the Dry Sludge program. They evaluated four program areas: energetic material formation, stability, initiation, and propagation. The panel evaluation included a site visit (July 13, 1999 and July 14, 1999) as well as a review of various reports and presentations by researchers involved in the program.

  10. Organization of the Optical Society of America Photonic Science Topical Meeting Series. Volume 14. Photorefractive Materials Effects, and Devices Held in Beverly, Massachusetts on 29-31 July 1991

    Science.gov (United States)

    1991-01-01

    1991 - Continued TUESDAY, JULY 30, 1991 - Continued 9:30 am 11:30 am TuA7 Synchrotron x-ray diffraction imaging of photorefrac- TuB5 Power...nitrogen laser for pulse excitation. (p. 232) Millerd, Steffen D. Koehler, Elsa M. Garmire, U. Southern California; Marvin B. Klein, Hughes Research...crystals and their gratings in barium titanate by high resolution monochromatic synchrotron x-ray diffraction imaging. The results that we report here

  11. Number Sense: Strategies for Helping Preschool through Grade 3 Children Develop Math Skills

    Science.gov (United States)

    Witzel, Bradley S.; Ferguson, Christine J.; Mink, Deborah V.

    2012-01-01

    Number sense development in young children has been linked to future math achievement in a manner similar to the way phonological awareness (i.e., children's awareness and use of sounds within a language to make meaning) has been linked to reading achievement (e.g., Kosanovich, Weinstein, & Goldman 2009). That is, they may be indicators of future…

  12. Environmental Affective Dispositions Scale (EADS): The Study of Validity and Reliability and Adaptation to Turkish

    Science.gov (United States)

    Fettahlioglu, Pinar; Timur, Serkan; Timur, Betül

    2016-01-01

    The aim of this study is to conduct a research under circumstances of Turkey about the validity and reliability of the Affective Tendencies towards Environmental Scale prepared by Yavetz, Goldman and Pe'er (2009). The translation of this scale to Turkish was done by the researchers and language specialists. And then, the scale was evaluated by the…

  13. Kinds of Learning and the Likelihood of Future True Beliefs: Reply to Jäger on Reliabilism and the Value Problem

    OpenAIRE

    Olsson, Erik J; Jönsson, Martin

    2011-01-01

    We reply to Christoph Jager's criticism of the conditional probability solution (CPS) to the value problem for reliabilism due to Goldman and Olsson (2009). We argue that while Jager raises some legitimate concerns about the compatibility of CPS with externalist epistemology, his objections do not in the end reduce the plausibility of that solution.

  14. Na+/K(+)pump activity in photoreceptors of the blowfly Calliphora : A model analysis based on membrane potential measurements

    NARCIS (Netherlands)

    Gerster, U; Stavenga, DG; Backhaus, W

    Na+/K+-pump activity and intracellular Na+ and K+ concentration changes in blowfly photoreceptors are derived from intracellular potential measurements in vivo with a model based on the Goldman-Hodgkin-Katz theory for membrane currents. The relation between the intracellular Na+ concentration and

  15. 76 FR 80873 - Food Source Attribution; Public Meeting

    Science.gov (United States)

    2011-12-27

    ... outline or summary of an oral presentation, contact: Juanita Yates, FDA, Center for Food Safety and Applied Nutrition, telephone: (240) 402-1731, email: [email protected] . To request special... the meeting, contact Dr. David Goldman, Assistant Administrator, Office of Public Health Science, USDA...

  16. Erazm Goldman’s List of Archives of Old Documents in the Kingdom [of Poland

    Directory of Open Access Journals (Sweden)

    Rafał Jaworski

    2017-12-01

    Full Text Available This edition concerns the 19th-century inventory of Old-Polish noble courts records and municipal records created by Erazm Goldman, an archivist in the Archives of Historical Records in Piotrków. Until now the inventory has been known only indirectly, through Adam Wolff’s publication. During World War II most of Old-Polish judicial and municipal records stored in the Archives of Historical Records in Warsaw were destroyed. Along with archival materials, also finding aids burnt down. In this situation Wolff, preparing a list of losses of pre-partition juducial and municipal records, used the Goldman’s inventory as a fundamental source about the fonds, their internal division and dates. The inventory was created probably between 1843 and 1860. The ground for this edition is a copy of the inventory made in 1872 by Goldman for a legal historian Romuald Hube. It seems that Goldman worked using lists of holdings of particular archives of historical records, produced periodically for the Governmental Committee for Justice. This resulted in dividing materials according to archives and Old-Polish judicial districts. Later the inventory enlists records of municipal courts and provincial courts, divided into series, with dates and numbers of books. In case of municipal records Goldman listed only these towns, which records were stored in a particular archives of historical records.

  17. Xu et al., Afr J Tradit Complement Altern Med. (2013) 10(2):356-367 ...

    African Journals Online (AJOL)

    AJTCAM

    , 50: 1352-1364. 13. von Moltke L.L., Weemhoff J.L., Bedir E., Khan I.A., Harmatz J.S., Goldman P. and Greenblatt D.J. (2004). Inhibition of human cytochromes P450 by components of Ginkgo biloba. J. Pharm. Pharmacol., 56: 1039-1044. 14.

  18. Turbulence in molecular clouds - A new diagnostic tool to probe their origin

    Science.gov (United States)

    Canuto, V. M.; Battaglia, A.

    1985-01-01

    A method is presented to uncover the instability responsible for the type of turbulence observed in molecular clouds and the value of the physical parameters of the 'placental medium' from which turbulence originated. The method utilizes the observational relation between velocities and sizes of molecular clouds, together with a recent model for large-scale turbulence (constructed by Canuto and Goldman, 1985).

  19. Bicuspid aortic valve

    Science.gov (United States)

    ... aortic disease. In: Otto CM, Bonow RO, eds. Valvular Heart Disease: A Companion to Braunwald’s Heart Disease . 4th ed. ... PA: Elsevier Saunders; 2014:chap 13. Carabello BA. Valvular heart disease. In: Goldman L, Schafer AI, eds. Goldman’s Cecil ...

  20. Investing against the wind : contagion during the recent financial crisis

    NARCIS (Netherlands)

    Lu, Liping; Wang, Chunyang

    2016-01-01

    This article examines the effect of Warren Buffett’s investment in Goldman Sachs on 24 September 2008, during the subprime mortgage crisis. Although this event is arguably perceived to be the biggest expression of confidence in the financial market during the crisis, by conducting event studies, we

  1. Brain-Based Devices for Neuromorphic Computer Systems

    Science.gov (United States)

    2013-07-01

    Science. 233(4771):1416-9. Goldman-Rakic, P.S. (1995). Cellular basis of working memory. Neuron. 14(3):477-85. Haider, B., Krause, M.R., Duque , A., Yu...Haider, B., Krause, M. R., Duque , A., Yu, Y., Touryan, J., Mazer, J. A., and McCormick, D. A. (2010). Synaptic and network mechanisms of sparse and

  2. Progressive-Era Resources on the World Wide Web.

    Science.gov (United States)

    Howenstein, Amanda

    1999-01-01

    Provides a list of Progressive-era websites with the address and a detailed description of each of the websites. Includes topics such as the womens suffrage movement, the Triangle Shirtwaist Factory fire, the Prohibition, labor-management conflicts, the Hull House, the Chicago fire, Emma Goldman, Progressive-era entertainment, and the Worlds Fair.…

  3. Speculative values and courtroom contestations

    NARCIS (Netherlands)

    de Goede, M.

    2015-01-01

    This article examines the trial of former Goldman Sachs employee Fabrice Tourre, who was held liable for securities fraud in 2013, and asks what it tells us about postcrisis understanding of politics and critique. What does it mean to hold Tourre individually liable amid the complex

  4. Evidence-Based Counseling Interventions with Children of Divorce: Implications for Elementary School Counselors

    Science.gov (United States)

    Connolly, Marianne E.; Green, Eric J.

    2009-01-01

    Parental divorce has become increasingly common for large numbers of families in schools (Lamden, King, & Goldman, 2002). This article addresses the effects of divorce on children and protective factors supporting their adjustment. Evidence-based interventions for children of divorce in elementary school counseling programs are discussed.…

  5. Oh No, Not the "A" Word! Proposing an "Anarchism" for Education

    Science.gov (United States)

    DeLeon, Abraham

    2008-01-01

    Anarchist theory has a long-standing history in political theory, sociology, and philosophy. As a radical discourse, anarchist theory pushes educators and researchers towards new conceptualizations of community, theory, and praxis. Early writers, like Joseph Proudhoun and Emma Goldman, to more contemporary anarchists, such as Noam Chomsky, have…

  6. Coming to See Objects of Knowledge: Guiding Student Conceptualization through Teacher Embodied Instruction in a Robotics Programming Class

    Science.gov (United States)

    Kwah, Helen

    2013-01-01

    This thesis explores the questions of how a teacher guides students to see concepts, and the role of gesture and gesture viewpoints in mediating the process of guidance. To examine these questions, two sociocultural theoretical frameworks--Radford's cultural-semiotic theory of knowledge objectification (e.g., 2003), and Goldman's Points of Viewing…

  7. Incorporating Feminist Standpoint Theory

    DEFF Research Database (Denmark)

    Ahlström, Kristoffer

    2005-01-01

    As has been noted by Alvin Goldman, there are some very interesting similarities between his Veritistic Social Epistemology (VSE) and Sandra Harding’s Feminist Standpoint Theory (FST). In the present paper, it is argued that these similarities are so significant as to motivate an incorporation...

  8. tropical OCTOBER

    African Journals Online (AJOL)

    presented with a history of low abdominal pain of six days' duration, dizziness and passage of mucoid ... complained of sudden abdominal pain and extreme weakness. Examination revealed stable vital signs and .... Goldman G A, Fish B, Ovadia J, and Tadir T. Heterotopic pregnancy after assisted reproductive technologies ...

  9. Manifestations of the MOMM Phenomenon II: Relevant Data on Professional Darwinism and Membership Composition.

    Science.gov (United States)

    Horan, John J.; And Others

    Horan (1989) reported that graduates and employees of four institutions (Minnesota, Ohio State, Maryland, and Missouri - the "MOMM Cartel") heavily dominate every science and practice organ of the American Psychological Association's Division 17 governing body. Goldman (1990) provided additional data indicating that egregious exclusion…

  10. 78 FR 68107 - Order Exempting Broker-Dealers Participating in the Proposed Global Offering of Meridian Energy...

    Science.gov (United States)

    2013-11-13

    ...''), Deutsche Bank AG, New Zealand Branch/Craigs Investment Partners Limited, Goldman Sachs New Zealand and... and Australia, and installment and partly paid structures have been used in numerous other transactions in New Zealand and Australia in recent years. Conclusion It is therefore ordered, that Joint Lead...

  11. 75 FR 53699 - Granting of Request for Early Termination of the Waiting Period Under the Premerger Notification...

    Science.gov (United States)

    2010-09-01

    ... status Party name 26-JUL-10 20100914 G Natural Gas Partners VIII, LP. G The Goldman Sachs Group, Inc. G... Company. G Cedar Power Corporation. G Cogentrix Operating Services Holdings LLC. G Raptor Holdings Company... International, Inc. 20100910 G Galaxy PEF Holding LLC. G Otera US Holding Inc. G CW Financial Services LLC...

  12. O'Neill: majanduse uut tõusu hakkavad vedama 15 riiki

    Index Scriptorium Estoniae

    2010-01-01

    Goldman Sachsi varahalduse juhi Jim O'Neilli hinnangul kujuneb keskmise ja suure tulu saajate arvu dramaatiline kasv BRIC-riikides (Brasiilia, Venemaa, India, Hiina) ja N-11 riikides (Mehhiko, Türgi, Korea, Iraan, Egiptus, Nigeeria, Pakistan, Filipiinid, Bangladesh, Vietnam) suurimaks tarbimist vedavaks jõuks maailmas lähema 10 aasta jooksul ja sealt edasi

  13. 78 FR 42436 - Procedures To Establish Appropriate Minimum Block Sizes for Large Notional Off-Facility Swaps and...

    Science.gov (United States)

    2013-07-16

    ... (ICE). Gold (COMEX and NYSE Liffe).. 2,500 troy oz. Goldman Sachs Commodity Index 5,000 times dollars... (NYMEX) 1,000 troy oz. PG&E Citygate Basis (ICE and 62,500 MMBtu. NYMEX). PJM Western Hub Real Time Off...). Platinum (NYMEX) 500 troy oz. Rainfall Index (CME)......... 10,000 times dollars. index. Rough Rice (CBOT...

  14. Identifying Arabic-Language Materials for Children That Promote Tolerance and Critical Thinking

    Science.gov (United States)

    2011-01-01

    grateful to Julie Taylor of RAND and Regan Gurung of the University of Wisconsin Green Bay for their care- ful reviews of this report. Finally, we owe...Islam, London: Routledge and Kegan Paul. Brewer, D. J., Augustine, C. H., Zellman, G. L., Ryan G. W., Goldman C. A., Stasz, C., and Constant, L. 2007

  15. Die prestasievooruitsigte in verskillende universitêre vakrigtings: 'n ...

    African Journals Online (AJOL)

    Furthermore, reasons for the present phenomenon proposed by Goldman and Hewitt (1975) were investigated by correlating objective indices of these potentially explanatory variables with the locally determined achievement prospect indices. Their suggestion that more objective facts had accumulated in the natural ...

  16. Daniel Bain lämmatas plekivabrikus puhkenud oktoobrirevolutsiooni / Andres Reimer

    Index Scriptorium Estoniae

    Reimer, Andres

    2005-01-01

    Investeerimispangad Goldman Sachs ja Deutshe Bank ning Venemaa terasehiiglase Severstal tütarfirma Severstallat üritasid Galvexit üle võtta. Väidetavalt sai Galvexi omanik ameeriklane Daniel Bain pankadele tagasimakstava summa USA investeerimisettevõttest. Lisa: Galvexi ajalugu. Vt. samas: Omanike teravad suhted

  17. Kogu maailma hõlmav supertsükkel / Fredy-Edwin Esse

    Index Scriptorium Estoniae

    Esse, Fredy-Edwin

    2011-01-01

    Goldman Sachs Groupi, Pricewaterhouse Coopersi ja London's Standard Chartered Banki makroökonomistid ennustavad majanduskasvu saabumist järgmistel aastakümnetel. Standard Charteredi peaökonomist Gerard Lyons prognoosib majanduse n.-ö. supertsüklit

  18. GENERAL SURGERY

    African Journals Online (AJOL)

    Cruveilhier J. Anatomie pathologique du corps humain. Paris: JB Balliere, 1835. 3. Goldman RL. Hamartomatous polyp of Brunner's gland. Gastroenterology. 1963;44:57-62. 4. Kellogg EL. Intussusception of the duodenum caused by adenoma originating in Brunner's glands. Med J Record. 1931;134:440-2. 5. Lempke RE.

  19. The Predictive Power of Evolutionary Biology and the Discovery of Eusociality in the Naked Mole-Rat.

    Science.gov (United States)

    Braude, Stanton

    1997-01-01

    Discusses how biologists use evolutionary theory and provides examples of how evolutionary biologists test hypotheses on specific modes of selection and evolution. Presents an example of the successful predictive power of one evolutionary hypothesis. Contains 38 references. (DDR)

  20. Higher Education and the American Dream

    OpenAIRE

    Lazerson, Marvin; Lazerson, Marvin

    2013-01-01

    "Marvin Lazerson’s new book is exactly what is needed: a readable, cogent explanation of how the U.S. can have the best system of higher education in the world, but also a system that seems to be coming apart at the seams.” —Susan Fuhrman, President Teachers College, Columbia University, President of the National Academy of Education "In prose remarkable for its clarity and analysis remarkable for its fair-mindedness, this volume delivers a penetrating, nuanced account of American universit...

  1. Polarized Light Scattering from Perfect and Perturbed Surfaces and Fundamental Scattering Systems

    Science.gov (United States)

    1992-02-29

    ob- one frequency, an extension of it to multiple-field interac- served in the elastically scattered light emitted from glass tions would follow the...that 8. V CeIll . A. A. Maradudin, A. M. Marvin, and A. R. McGurn, can explain only gross scattering features. It is inde "Some aspects of light...and a surface of index n a 10.0 - 0.01. Such a surface could be made with a series of 1/4-wave dielectric layers on a glass substrate. It Is more

  2. Politically Correct Racism and the Geisha Novel: The Psychology of Sophisticated Racism Mirrors that of Ethnic Jokes

    OpenAIRE

    TANAKA, Tomoyuki

    2006-01-01

    In Section 1, politically correct racism (PC racism) is defined as an act with racist intent, justified by righteous appearance, with popularity or near-total acceptance because of its righteous appearance. In Section 2, after presenting a theory of jokes based on analyses by Sigmund Freud and Marvin Minsky, I show that the pleasure one derives from PC racism is similar to that derived from ethnic jokes. In Section 3, I point out the inaccuracies and prejudice contained in the novel Memoirs o...

  3. Census Report, Volume II, 1967 through 1974. Sanitized Version.

    Science.gov (United States)

    1985-08-15

    SUNDSTROM, OSCAR J. 3 098229 0600 SUTHERLAND , ROBERT M. 3 008281 0638 SUTHERLAND , WILLIAM C. 3 094809 0688 SUTTEN, ADRIAN P. 2 6 642 76 Personnel Dose...BELTZ, GLEN D. 2 0607 "BENDER, KENNETH E. 2 0638 BENDINELLI, RALPH A. 2 0649 BERG, CHARLES A. 2 0638 BERG, CLINT 2 0680 148 Personnel Dose Information...MARVIN B. 2 06801 SUMMA, WILLIAM J. 2 0680 SUPPES, DUANE A. 2 0793 SUTHERLAND , ROBERT M. 2 0638 SUTTEN, ADRIAN P. 2 0642 SWAFFORD, FRED G. 3 092765 0602

  4. MIZEX (Marginal Ice Zone Experiment) 1987 SAR (Synthetic Aperture Radar) Data Summary.

    Science.gov (United States)

    1988-02-01

    by Messors Peter Button, Mathias Fruhwirth, Ralph Webster, Marvin Keyser, Dean Butler, Clay Atcheson, and Keith Tennant. The cooperative data...A (7 00 w m) m-- 0) m enJ. N) N1I N &lN U)) V- 1-1 ** 2 i ~0 v- 02D It P . ’i N 4 N N N ZEc . 0) 0) 0) 0) 0 c rIf Lo La U) LVi) N NN , U) ( U)I Z < C.1

  5. Minimally invasive aesthetic procedures in young adults

    Directory of Open Access Journals (Sweden)

    Wollina U

    2011-03-01

    Full Text Available Uwe Wollina1, Alberto Goldman21Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, Germany; 2Clinica Goldman, Porto Alegre, Rio Grande du Sul, BrazilAbstract: Age is a significant factor in modifying specific needs when it comes to medical aesthetic procedures. In this review we will focus on young adults in their third decade of life and review minimally invasive aesthetic procedures other than cosmetics and cosmeceuticals. Correction of asymmetries, correction after body modifying procedures, and facial sculpturing are important issues for young adults. The implication of aesthetic medicine as part of preventive medicine is a major ethical challenge that differentiates aesthetic medicine from fashion.Keywords: acne scars, ice pick scars, boxcar scars, fillers 

  6. Long-range cargo transport on crowded microtubules: The motor jamming mechanism

    Science.gov (United States)

    Rossi, Lucas W.; Radtke, Paul K.; Goldman, Carla

    2014-05-01

    The hopping model for cargo transport by molecular motors introduced in Goldman and Sena (2009), Goldman (2010) is extended here in order to incorporate the movement of cargo-motor complexes (C-MC). Hopping processes in this context express the possibility for cargo to be exchanged between neighboring motors at a microtubule where the transport takes place. Jamming of motors is essential for cargos to execute long-range movement in this way. Results from computer simulations accompanied by a mean-field analysis of the extended model confirm our previous analytical results and suggests that an interplay between cargo hopping and the movement of the C-MC’s would control the efficiency of cargo transfer and cargo delivery in these model systems.

  7. A rare type of Usher's syndrome.

    Science.gov (United States)

    Antunica, Antonela Gverović; Kastelan, Snjezana; Bućan, Kajo; Ivanković, Mira; Radman, Maja; Karaman, Ksenija

    2013-12-01

    A case is presented of a very rare type of Usher's syndrome detected in a 30-year-old woman in her 28th week of pregnancy. She reported left eye visual impairment with a one-month history. She underwent standard ophthalmologic examination with additional procedures scheduled after childbirth, including fluorescein angiography, visual field (Goldman and Octopus) and electroretinography. Fundus examination revealed pallor of the optic disk, diffuse retinal blood vessel narrowing, no retinal pigmentation, left macular edema, vitreous liquefaction, and posterior vitreous detachment. Goldman perimetry showed narrowing of all isopters to 10 degrees, and Octopus perimetry showed peripheral decrease of retinal sensitivity. Electroretinography confirmed the diagnosis of retinitis pigmentosa sine pigmento. Upon collecting case history records, hearing disorders originating from childhood were discovered. To our knowledge, this type of retinitis in Usher's syndrome has been reported only once in the available literature.

  8. A Pilot Investigation of Speech Sound Disorder Intervention Delivered by Telehealth to School-Age Children

    Directory of Open Access Journals (Sweden)

    Sue Grogan-Johnson

    2011-05-01

    Full Text Available This article describes a school-based telehealth service delivery model and reports outcomes made by school-age students with speech sound disorders in a rural Ohio school district. Speech therapy using computer-based speech sound intervention materials was provided either by live interactive videoconferencing (telehealth, or conventional side-by-side intervention.  Progress was measured using pre- and post-intervention scores on the Goldman Fristoe Test of Articulation-2 (Goldman & Fristoe, 2002. Students in both service delivery models made significant improvements in speech sound production, with students in the telehealth condition demonstrating greater mastery of their Individual Education Plan (IEP goals. Live interactive videoconferencing thus appears to be a viable method for delivering intervention for speech sound disorders to children in a rural, public school setting. Keywords:  Telehealth, telerehabilitation, videoconferencing, speech sound disorder, speech therapy, speech-language pathology; E-Helper

  9. Risiko Likuiditas Bank dan Asset Liabilities Management

    OpenAIRE

    Lesmana, Iwan

    2007-01-01

    Uquidity is of critical importance to companies in the banking services sector. Most failures of financialintermediaries have occured in large part due to insufficient liquidity resulting from adverse circumstances.Goldman Sachs has in piace a comprehensive set of liquidity and funding policies that are intended tomaintain significant flexibility to address specific and broader industry or market liquidity events.In asset liabilities mal1agement or liquidity management, liquidity risk is mana...

  10. United States Air Force Graduate Student Summer Support Program (1985). Technical Report. Volume 2.

    Science.gov (United States)

    1985-12-01

    will greatly facilitate the examination of clinical specimens. Probes which will hybridize with genus , species, and genotypes will be developed. Along...hybridize with genus , species, and genotypes will be developed. Along with this immediate benefit, the DNA probe will also impact upon broader areas of...attrition rate include traditional military stereotypes and symbolism (Moskos, 1970; Goldman, 1973), military socialization (Janowitz & Little, 1974; Arkin

  11. ARO/ARL Site Visit Project Review Presentation

    Science.gov (United States)

    2012-07-01

    hemodynamic activity. 7/11/2012 Challenges 10 complicated equipment gradient artifact BCG artifact How to combine the data? bias field auditory...noise 7/11/2012 11 A B C + + – – Our Solutions EEG+ BCG BCG 7/11/2012 12 (Goldman et al., Neuroimage 2009) Observing latent...Discrimination Results model human subjects Neurometric curve NOT optimized to match psychometric curve! human subjects model ( matrix word

  12. Üleilmse finantskriisi leevenemist silmapiiril veel ei paista / Erik Aru

    Index Scriptorium Estoniae

    Aru, Erik

    2007-01-01

    Maailma rahaturgudel kestab veel krediidikriis. Mitme vaatleja hinnangul näitab see, et kriis pole lahenenud ka pärast intressimäära langetamist, et tegemist on tõsise probleemiga. Investeerimispanga Goldman Sachs peaökonomist Jan Hatzius soovitab intressi veelgi vähendada. Hinnanguid kahjumi suuruse kohta. Lisad: Pangandus - pidev kriiside allikas; Euroopa keskpankureid inflatsioon ei loksuta

  13. Field Test Data for Detecting Vibrations of a Building Using High-Speed Video Cameras

    Science.gov (United States)

    2017-10-01

    ARL-TR-8185 ● OCT 2017 US Army Research Laboratory Field Test Data for Detecting Vibrations of a Building Using High-Speed Video...Field Test Data for Detecting Vibrations of a Building Using High-Speed Video Cameras by Caitlin P Conn and Geoffrey H Goldman Sensors and...June 2016 – October 2017 4. TITLE AND SUBTITLE Field Test Data for Detecting Vibrations of a Building Using High-Speed Video Cameras 5a. CONTRACT

  14. The STRIVE-ONR Project: Stress Resistance in Virtual Environments

    Science.gov (United States)

    2015-07-29

    from the Virtual Iraq/Afghanistan Virtual Reality Exposure Therapy (VRET) system at the University of Southern California Institute for Creative...better sense of health outcomes; that is, "how the social environment exerts a cumulative impact on the physical and mental well being of individuals...levels with functional decline in elderly men and women. Geriatrics & gerontology international, 9 3, 282-289. Goldman, N., Turra, C. M., Glei, D

  15. The Second Garnet Compendium: Collected Papers 1990-1992.

    Science.gov (United States)

    1993-02-01

    BELIEF Robert Goldman Russell Almond 33. Tulane University, CS 12. The MITRE Corporation THESEUS AIMI (An Intelligent Multimedia Interface) Raymond Lang...These are images of windows from the THESEUS application used by the Tulanc University Computer Science Department on guided tours of the department given...to visiting high school seniors and other interested paries. THESEUS is intended to be used as part of a presentation on what the study of computcr

  16. Study and Design of High G Augmentation Devices for Flight Simulators

    Science.gov (United States)

    1981-12-01

    Dana Rogers in the modeling of grayout, Dr. Ralph Goldman in the matter of localized skin heating and cooling, and Dr. Emilio Bizzi in the area of...Temperature on Human Tolerance to +Gz Ac- celeration," Journal of Applied Physiology, Vol. 33, No. 4:418-420, Oct., (1972). 5. Anderson, B., Saltzman , H.A...Correspondence, National Atro- nautics and Space Administration, June (197E). 270. Young, L., Unpublished Notes of Meeting with Dana Rogers, (1978). 271

  17. Adolescent literacy: learning and understanding content.

    Science.gov (United States)

    Goldman, Susan R

    2012-01-01

    Learning to read--amazing as it is to small children and their parents--is one thing. Reading to learn, explains Susan Goldman of the University of Illinois at Chicago, is quite another. Are today's students able to use reading and writing to acquire knowledge, solve problems, and make decisions in academic, personal, and professional arenas? Do they have the literacy skills necessary to meet the demands of the twenty-first century? To answer these questions, Goldman describes the increasingly complex comprehension, reasoning skills, and knowledge that students need as they progress through school and surveys what researchers and educators know about how to teach those skills. Successfully reading to learn requires the ability to analyze, synthesize, and evaluate information from multiple sources, Goldman writes. Effective readers must be able to apply different knowledge, reading, and reasoning processes to different types of content, from fiction to history and science, to news accounts and user manuals. They must assess sources of information for relevance, reliability, impartiality, and completeness. And they must connect information across multiple sources. In short, successful readers must not only use general reading skills but also pay close attention to discipline-specific processes. Goldman reviews the evidence on three different instructional approaches to reading to learn: general comprehension strategies, classroom discussion, and disciplinary content instruction. She argues that building the literacy skills necessary for U.S. students to read comprehensively and critically and to learn content in a variety of disciplines should be a primary responsibility for all of the nation's teachers. But outside of English, few subject-area teachers are aware of the need to teach subject-area reading comprehension skills, nor have they had opportunities to learn them themselves. Building the capacity of all teachers to meet the literacy needs of today's students

  18. Physiological Sociology. Endocrine Correlates of Status Behaviors,

    Science.gov (United States)

    1975-01-01

    affiliative bonding. One psychiatric illness which manifests itself in social structural relationships in a profound was is sociopathic behavior. By the...very nature of the sociopathic individual, persons with the disorder display altered social behavior (Robins, 1966). The question as to whether such...Oxford: Oxford University Press, 1971. Goldman, H., Lindner, L., Dinitz, S., and Allen, H. The simple sociopath : Physiologic and sociologic

  19. Chronic myeloid leukemia: reminiscences and dreams

    Science.gov (United States)

    Mughal, Tariq I.; Radich, Jerald P.; Deininger, Michael W.; Apperley, Jane F.; Hughes, Timothy P.; Harrison, Christine J.; Gambacorti-Passerini, Carlo; Saglio, Giuseppe; Cortes, Jorge; Daley, George Q.

    2016-01-01

    With the deaths of Janet Rowley and John Goldman in December 2013, the world lost two pioneers in the field of chronic myeloid leukemia. In 1973, Janet Rowley, unraveled the cytogenetic anatomy of the Philadelphia chromosome, which subsequently led to the identification of the BCR-ABL1 fusion gene and its principal pathogenetic role in the development of chronic myeloid leukemia. This work was also of major importance to support the idea that cytogenetic changes were drivers of leukemogenesis. John Goldman originally made seminal contributions to the use of autologous and allogeneic stem cell transplantation from the late 1970s onwards. Then, in collaboration with Brian Druker, he led efforts to develop ABL1 tyrosine kinase inhibitors for the treatment of patients with chronic myeloid leukemia in the late 1990s. He also led the global efforts to develop and harmonize methodology for molecular monitoring, and was an indefatigable organizer of international conferences. These conferences brought together clinicians and scientists, and accelerated the adoption of new therapies. The abundance of praise, tributes and testimonies expressed by many serve to illustrate the indelible impressions these two passionate and affable scholars made on so many people’s lives. This tribute provides an outline of the remarkable story of chronic myeloid leukemia, and in writing it, it is clear that the historical triumph of biomedical science over this leukemia cannot be considered without appreciating the work of both Janet Rowley and John Goldman. PMID:27132280

  20. From Princesa to Princess with a Prince: 1994 and 2001 Fernanda's Stories

    Directory of Open Access Journals (Sweden)

    Polina Shvanyukova

    2012-12-01

    Full Text Available In an analysis of what presents itself as a cinematic transposition of a literary text, it is difficult to break away from the “binary oppositions [...] literature versus cinema, high culture versus mass culture, original versus copy" (James Naremore. In the case of Princesa (2001, directed by Henrique Goldman, it is questionable whether we can speak about an adaptation at all. As Goldman himself stated, he got the idea for making the film after reading the eponymous 1994 book written by Fernanda Farias de Albuquerque in collaboration with Maurizio Jannelli. In his film, Goldman has made drastic changes to the autobiographical story of Fernanda, the Brazilian transsexual prostitute who travels to Europe in order to earn money for her sex-change operation. However, the film was in fact dedicated to the memory of the real Fernanda, who had passed away in the meantime. In this contribution, the two works will be examined in their relationship to a third source-text by paying special attention to the processes of worldmaking as developed in Nelson Goodman's seminal 1978 book and expanded in the 2010 collection of essays Cultural Ways of Worldmaking. Media and Narratives.

  1. Physiological Adaptations of Arctic Mammals.

    Science.gov (United States)

    1975-01-01

    Katie Persons, Biologist Peter ’Ringens, Biochemist Oliver Heroux, Ph.D., Physiologist Edward Koo, Biologist Martin Steiner, Biologist Louise Janes...and aspects . This manuscript includes about one-fifth of our data on this topic, obtained in the last two years. Of course, my motivation for studying...ARCTIC LEIMINGS Progressive depression of renal function during hypo- thermia generally is presupposed. Data gathered incidentally as part of a

  2. Biosensors and environmental health

    National Research Council Canada - National Science Library

    Preedy, Victor R; Patel, Vinood B

    2012-01-01

    .... Contributors are leading authorities and the book is essential reading for environmental scientists, toxicologists, medical doctors, health care professionals, pathologists, biologists, biochemists...

  3. Tides, surges and mean sea-level

    National Research Council Canada - National Science Library

    Pugh, D. T

    1987-01-01

    .... These include hydrographers, marine and coastal engineers, geologists who specialize in beach or marine sedimentation processes, and biologists concerned with the ways in which living organisms adapt...

  4. A Novel Functional Screen for New Breast Cancer Genes

    National Research Council Canada - National Science Library

    King, Mary-Claire; Welcsh, Piri L

    2005-01-01

    Genetic instability is a hallmark of tumor development. Mechanisms for maintenance of genomic stability are heterogeneous and identification of the genes responsible a critical goal of cancer biologists...

  5. A conversation with Drs. Kaplan and Moser about conflicting data, confusing results, and some recent treatment recommendations for the management of hypertension.

    Science.gov (United States)

    Post, Wendy; Moser, Marvin; Kaplan, Norman

    2005-10-01

    Following a hypertension symposium in Baltimore, MD, on June 1, 2005, Dr. Wendy Post from the Johns Hopkins University School of Medicine, Baltimore, MD, had the opportunity to interview two of the outstanding hypertension experts in the United States on several controversial issues in hypertension management. Dr. Norman Kaplan is Clinical Professor of Medicine at the Southwestern Health Science Center in Dallas, TX, and Dr. Marvin Moser is Clinical Professor of Medicine at the Yale University School of Medicine, New Haven, CT. Both have been leaders in the field of hypertension treatment and education for more than 40 years. Dr. Kaplan's book Clinical Hypertension has been a standard textbook since 1973 and is now in its ninth edition. Dr. Marvin Moser was the Senior Medical Consultant to the National High Blood Pressure Education Program from 1974 to 2002 and was Chairman of the first Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure and a member of the six subsequent committees. His book Clinical Management of Hypertension is in its seventh edition. Drs. Moser and Kaplan were corecipients of the 2004 International Society of Hypertension Award for Outstanding Contributions to Hypertension Treatment and Education and have lectured extensively throughout the United States and overseas.

  6. Cognitive styles of Forest Service scientists and managers in the Pacific Northwest.

    Science.gov (United States)

    Andrew B. Carey

    1997-01-01

    Preferences of executives, foresters, and biologists of the Pacific Northwest Research Station and executives, District Rangers, foresters, engineers, and biologists of the Pacific Northwest Region, National Forest System (USDA Forest Service), were compared for various thinking styles. Herrmann brain dominance profiles from 230 scientists and managers were drawn from...

  7. A Linked Series of Laboratory Exercises in Molecular Biology Utilizing Bioinformatics and GFP

    Science.gov (United States)

    Medin, Carey L.; Nolin, Katie L.

    2011-01-01

    Molecular biologists commonly use bioinformatics to map and analyze DNA and protein sequences and to align different DNA and protein sequences for comparison. Additionally, biologists can create and view 3D models of protein structures to further understand intramolecular interactions. The primary goal of this 10-week laboratory was to introduce…

  8. Creating to understand – developmental biology meets engineering in Paris

    NARCIS (Netherlands)

    Kicheva, Anna; Rivron, Nicolas C.

    2017-01-01

    In November 2016, developmental biologists, synthetic biologists and engineers gathered in Paris for a meeting called ‘Engineering the embryo’. The participants shared an interest in exploring how synthetic systems can reveal new principles of embryonic development, and how the in vitro manipulation

  9. The simplest formal argument for fitness optimization

    Indian Academy of Sciences (India)

    The Formal Darwinism Project aims to provide a formal argument linking population genetics to fitness optimization, which of necessity includes defining fitness. This bridges the gulf between those biologists who assume that natural selection leads to something close to fitness optimization and those biologists who believe ...

  10. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    The neural crest has long fascinated developmental biologists, and, increasingly over the past decades, evolutionary and evolutionary developmental biologists. The neural crest is the name given to the fold of ectoderm at the junction between neural and epidermal ectoderm in neurula-stage vertebrate embryos.

  11. Epigenetics: Making your mark on DNA

    Science.gov (United States)

    Harada, Bryan T.; He, Chuan

    2017-11-01

    Understanding the biological roles of modifications to DNA, RNA and proteins is critical to revealing how cells regulate gene expression in development and disease. Two papers now present a combination of new tools and discoveries that could enable biologists and chemical biologists to better study epigenetic regulation in mammals.

  12. IsoBank – Stable isotope ecology in the age of ‘Big Data’

    Science.gov (United States)

    Stable isotopes ratios provide valuable information to fish biologists working in a diverse range of fields: e.g. ecologists, population biologists and fishery managers. Ecologists take advantage of stable isotope ratios to provide information on the diet and migration history of consumers or when a...

  13. Editor-in-Chief

    Directory of Open Access Journals (Sweden)

    M Yavuz COŞKUN

    2013-06-01

    Full Text Available Andrejs Geske (University of Latvia, Latvia B. N. Ghosh (Eastern Med. Univ. North Cyprus Bayram Ürekli (University of Selçuk, Türkiye Erdinç Didar (American University, Bulgaria Ercan Tatlıdil (University of Ege, Türkiye Erman Artun (University of Çukurova, Türkiye Hikmet Y. Celkan (University of Gaziantep, Türkiye Hüseyin Bağcı (METU, Türkiye Jean Crombois (American University, Bulgaria Kemal Silay (Indiana University, USA Lelio Iapadre (University of L'Aquila, Italy Michael Goldman (University of Minnesota, USA

  14. Systematic Analysis of the Functional Relevance of Nuclear Structure and Mechanics in Breast Cancer Progression

    Science.gov (United States)

    2014-07-01

    accepted 12 June 2014) Associate Editor David Schaffer oversaw the review of this article. Abstract—Cell motility plays a critical role in many...Adam SA, Shumaker DK, Kinjo M, Cremer T, Goldman RD (2008) The A- and B-type nuclear lamin networks: micro- domains involved in chromatin organization...Irwin A. Eydelnant¶, Don E. Olins, Ada L. Olins, Harald Herrmann**, David A. Weitz¶, and Jan Lammerding§‡‡ From the ‡Department of Integrative Biology

  15. Selective DNA-Mediated Assembly of Gold Nanoparticles on Electroded Substrates

    Science.gov (United States)

    2008-06-01

    might use the Watson - Crick base-pairing of DNA as a means for ultrahigh-precision engineering is well- known.5,6 The idea is to use the highly specific...Selective DNA -Mediated Assembly of Gold Nanoparticles on Electroded Substrates K. E. Sapsford,†,‡,∇ D. Park,§ E. R. Goldman,‡ E. E. Foos,| S. A...electrodes via DNA hybridization. Protocols are demonstrated for maximizing selectivity and coverage using 15mers as the active binding agents. Detailed

  16. Leaders break ground for INFINITY

    Science.gov (United States)

    2008-01-01

    Community leaders from Mississippi and Louisiana break ground for the new INFINITY at NASA Stennis Space Center facility during a Nov. 20 ceremony. Groundbreaking participants included (l to r): Gottfried Construction representative John Smith, Mississippi Highway Commissioner Wayne Brown, INFINITY board member and Apollo 13 astronaut Fred Haise, Stennis Director Gene Goldman, Studio South representative David Hardy, Leo Seal Jr. family representative Virginia Wagner, Hancock Bank President George Schloegel, Mississippi Rep. J.P. Compretta, Mississippi Band of Choctaw Indians representative Charlie Benn and Louisiana Sen. A.G. Crowe.

  17. A novel NR2E3 gene mutation in autosomal recessive retinitis pigmentosa with cystic maculopathy

    OpenAIRE

    Mahajan, D.; Votruba, Marcela

    2017-01-01

    NR2E3 is a gene that encodes for photoreceptor cell specific nuclear receptor, which is involved in cone proliferation. The splice site mutation 119-2A>C in NR2E3 (15q23) has been previously reported to underlie recessive enhanced cone S sensitivity syndrome, clumped pigmentary retinal degeneration, Goldman-Favre syndrome and also autosomal dominant and autosomal recessive retinitis pigmentosa (RP). However, the mutation c 571 + 2 T > C in NR2E3 has not been previously reported with retinal d...

  18. The Anatomy of the Gyroscope. Part 3

    Science.gov (United States)

    1990-03-01

    parts of the optical train by gyroscopic means; one of the first is that of JENSEN 1JS 2829557 (1958) who proposes a Porro - prism binocular telescope...to the ideas of JENSEN using Porro - prisms but we have neglected until now to refer to the work of KAESTNER who using porro - prisms and counterweights...CLEMENCE G.M. DYNAMICS OP THE SOLAR SYSTEM IBID pp. 2.60-2.68 ** See N.M.R. nuclear magnetic resonance , discovered 1945. ABRAGAM. A and GOLDMAN. M

  19. Analýza vybraného segmentu ICT: analýza trhu e-commerce

    OpenAIRE

    Kožušník, Martin

    2011-01-01

    This work focuses on market analysis of e-Commerce in the "broad" concept. The main goal is to provide a comprehensive view of e-Commerce market in segments B2B, B2C, C2C, C2B including paid and open source e-Commerce platforms. Capture the current state of market leaders in various segments. The analysis used a freely available analysis published by analytical (eg Euromonitor, Goldman Sachs, internetretailer.com), statistical data from the ČSÚ, Eurostat. To determine the market leaders have ...

  20. Building a sustainable future - The effects of CSR-finance on national oil companies

    Energy Technology Data Exchange (ETDEWEB)

    Thakur, Vishal

    2010-09-15

    Since the release of Goldman Sach's 'Path to 2050' report, arguing the combined economies of Brazil, Russia, India and China, would ellipse the economies of the current richest countries by 2050, the BRIC countries have garnered global attention. As demand for oil in these nations increases, NOCs within the BRIC have gone beyond national borders for exploration and financing - giving rise to concerns over emerging policies, objectives and priorities. The purpose of this paper is to examine NOCs of the BRIC and their compliance with international standards of corporate social responsibility and their effects through international capital markets.

  1. The enduring legacy of the “constant-field equation” in membrane ion transport

    Science.gov (United States)

    2017-01-01

    In 1943, David Goldman published a seminal paper in The Journal of General Physiology that reported a concise expression for the membrane current as a function of ion concentrations and voltage. This body of work was, and still is, the theoretical pillar used to interpret the relationship between a cell’s membrane potential and its external and/or internal ionic composition. Here, we describe from an historical perspective the theory underlying the constant-field equation and its application to membrane ion transport. PMID:28931632

  2. Reliability of the Nidek NT-1000 non contact tonometer.

    Science.gov (United States)

    Van de Velde, T; Zeyen, T

    1995-01-01

    In this prospective study, we compared the intraocular pressure (IOP) readings of 100 patients measured with the Goldmann applanation tonometer and the Nidek NT-1000 pneumotonometer. The correlation coefficient between the Goldmann and Nidek readings was 0.86. On the average the pneumotonometer overestimated the intraocular pressure with 0.43 mm Hg. The Nidek NT-1000 non contact tonometer can be used for screening purposes provided an appropriately low IOP value is used to indicate the need for further assessment with the Goldman applanation tonometer.

  3. Building a sustainable future - The effects of CSR-finance on national oil companies

    Energy Technology Data Exchange (ETDEWEB)

    Thakur, Vishal

    2010-09-15

    Since the release of Goldman Sach's 'Path to 2050' report, arguing the combined economies of Brazil, Russia, India and China, would ellipse the economies of the current richest countries by 2050, the BRIC countries have garnered global attention. As demand for oil in these nations increases, NOCs within the BRIC have gone beyond national borders for exploration and financing - giving rise to concerns over emerging policies, objectives and priorities. The purpose of this paper is to examine NOCs of the BRIC and their compliance with international standards of corporate social responsibility and their effects through international capital markets.

  4. 20th Anniversary Conference on World Bank Administrative Tribunal

    CERN Document Server

    2000-01-01

    Contents :"Review of discretionary power by international administrative tribunals" by Michel Gentot, "Checks exerted by administrative tribunals over the discretionary powers of international organizations" by Nicolas Valticos, "Comments" by Ranjan (C.F.) Amerasinghe, "The review of managerial discretion by international administrative tribunals" by Francisco Orrego Vicuña, "Some practical issue arising in international administrative tribunals" by Nassib G. Ziadé, "Aspects of judicial review of administrative action in the WBAT with comparative remarks" by Spyridon Flogaitis, "The International Monetary Fund Administrative Tribunal : its first six years" by Celia Goldman

  5. USAF Summer Research Program - 1994 Summer Faculty Research Program Final Reports, Volume 5B, Wright Laboratory

    Science.gov (United States)

    1994-12-01

    S.K. Streiffer, B.M. Lairson, E.M. Zielinski , T. Umezawa, T.H. Geballe, and J.C. Bravman, Proc 50th Annual Meefrng of EMSA, edited by G.W. Bailey...Theory team at WL/AART-2: Dave Gadd, Mike Noviskey, Jeff Goldman; and also Chris Vogt, Mark Axtel, John Carroll, and Craig Files, who all contributed to...modification work on the wind tunnel were done by Dave Driscoll at the AFIT shop. We thank him for his steady and careful efforts, especially for the cast

  6. Coming to see objects of knowledge: Guiding student conceptualization through teacher embodied instruction in a robotics programming class

    Science.gov (United States)

    Kwah, Helen

    This thesis explores the questions of how a teacher guides students to see concepts, and the role of gesture and gesture viewpoints in mediating the process of guidance. To examine these questions, two sociocultural theoretical frameworks--Radford's cultural-semiotic theory of knowledge objectification (e.g., 2003), and Goldman's Points of Viewing theory (e.g., 2007)--were applied to conduct a microanalytic, explanatory case study of the instructional activity of an exemplary teacher and his students in a middle school robotics programming class. According to Radford, students acquire concepts as they draw upon semiotic resources such as language and gesture to generalize and objectify initially concrete perceptions and actions. I applied Radford's framework to explain the mediations that a teacher might enact in guiding students to objectify and see concepts. Furthermore, I focused on gesture as semiotic means because of emergent research on gesture's role in communicating the visuospatial imagery that underlies math/ scientific concepts. I extended the view of gestures to the viewpoints constructed in gesture, and applied Goldman's theory to explain how perspectives might be actively constructed and shared in the process of guiding student conceptualization. Data was collected over a semester through participant observation, field notes, teacher and student interviews, and reviews of artifacts. Multimodal microanalyses were conducted on video data from eight class sessions. The findings provide confirmations and some disconfirmations about the applicability of Radford's and Goldman's theories for explaining a teacher's process of guiding student conceptualization. Notably, some of Radford's notions about de-contextualization and symbolic generalizations were not confirmed. Overall, the findings are summarized through three themes including, grounding, and perceptual organizers as two ways that gesture and other means served to both index and identify action

  7. Satellite and Missile Data Generation for AIS.

    Science.gov (United States)

    1979-12-01

    for the Study of Artificiel Intelli- gence and the Simulation of Behaviour , July 1976, 104-117. Engel, E.S. & Granda, R.E. Guidelines for Man/Display...A. Implicit Causality In Verbs. Linquistic Inquire, 5(3), Sum- mer 1974, 464-469. 6-6 Garvey, C., Caramazza, A. and Yates, J. Factors Influencing ...Intelligence Laboratory, Stanford University, 1974. Goldman, N.M. Conceptual Generation. in: Schank 1975, 289-371. Goldstein, I.P. and Roberts, R. B. NUDGE

  8. JPRS Report, Soviet Union, International Affairs

    Science.gov (United States)

    1989-09-11

    8217 pens can fire further than guns. That means that I who ’charge’ these guns must keep my powder dry." That is what Gerasimov is all about. You expect... GUM and TsUM. On the desk Professor Marshall Goldman, deputy director of the Russian center, we saw even a whole tank column and prime movers with...intensification of direct investments in the present or the foreseeable future. In addition, no one can guar - antee that the amount of profit

  9. Beyond triage: the diagnostic accuracy of emergency department nursing staff risk assessment in patients with suspected acute coronary syndromes.

    Science.gov (United States)

    Carlton, Edward Watts; Khattab, Ahmed; Greaves, Kim

    2016-02-01

    To establish the accuracy of emergency department (ED) nursing staff risk assessment using an established chest pain risk score alone and when incorporated with presentation high-sensitivity troponin testing as part of an accelerated diagnostic protocol (ADP). Prospective observational study comparing nursing and physician risk assessment using the modified Goldman (m-Goldman) score and a predefined ADP, incorporating presentation high-sensitivity troponin. A UK District ED. Consecutive patients, aged ≥18, with suspected cardiac chest pain and non-ischaemic ECG, for whom the treating physician determined serial troponin testing was required. 30-day major adverse cardiac events (MACE). 960 participants were recruited. 912/960 (95.0%) had m-Goldman scores recorded by physicians and 745/960 (77.6%) by nursing staff. The area under the curve of the m-Goldman score in predicting 30-day MACE was 0.647 (95% CI 0.594 to 0.700) for physicians and 0.572 (95% CI 0.510 to 0.634) for nursing staff (p=0.09). When incorporated into an ADP, sensitivity for the rule-out of MACE was 99.2% (95% CI 94.8% to 100%) and 96.7% (90.3% to 99.2%) for physicians and nurses, respectively. One patient in the physician group (0.3%) and three patients (1.1%) in the nursing group were classified as low risk yet had MACE. There was fair agreement in the identification of low-risk patients (kappa 0.31, 95% CI 0.24 to 0.38). The diagnostic accuracy of ED nursing staff risk assessment is similar to that of ED physicians and interobserver reliability between assessor groups is fair. When incorporating high-sensitivity troponin testing, a nurse-led ADP has a miss rate of 1.1% for MACE at 30 days. Controlled Trials Database (ISRCTN no. 21109279). Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  10. Social Epistemology: 5 Questions

    DEFF Research Database (Denmark)

    Social Epistemology: 5 Questions is a collection of interviews with some of the world’s most influential scholars working on social epistemology from a range of disciplinary perspectives. We hear their views on social epistemology; its aim, scope, use, broader intellectual environment, future...... direction, and how the work of the interviewees fits in these respects. Interviews with David Bloor, Cristina Bicchieri, Richard Bradley, Lorraine Code, Hans van Ditmarsch, Miranda Fricker, Steve Fuller, Sanford Goldberg, Alvin Goldman, Philip Kitcher, Martin Kusch, Jennifer Lackey, Helen E. Longino, Philip...

  11. The philosophy of modelling or does the philosophy of biology have any use?

    Science.gov (United States)

    Orzack, Steven Hecht

    2012-01-19

    Biologists in search of answers to real-world issues such as the ecological consequences of global warming, the design of species' conservation plans, understanding landscape dynamics and understanding gene expression make decisions constantly that are based on a 'philosophical' stance as to how to create and test explanations of an observed phenomenon. For better or for worse, some kind of philosophy is an integral part of the doing of biology. Given this, it is more important than ever to undertake a practical assessment of what philosophy does mean and should mean to biologists. Here, I address three questions: should biologists pay any attention to 'philosophy'; should biologists pay any attention to 'philosophy of biology'; and should biologists pay any attention to the philosophy of biology literature on modelling? I describe why the last question is easily answered affirmatively, with the proviso that the practical benefits to be gained by biologists from this literature will be directly proportional to the extent to which biologists understand 'philosophy' to be a part of biology, not apart from biology.

  12. Contingencies and metacontingencies: Toward a synthesis of behavior analysis and cultural materialism

    Science.gov (United States)

    Glenn, Sigrid S.

    1988-01-01

    A synthesis of cultural materialism and behavior analysis might increase the scientific and technological value of both fields. Conceptual and substantive relations between the two fields show important similarities, particularly with regard to the causal role of the environment in behavioral and cultural evolution. Key concepts in Marvin Harris's cultural materialist theories are outlined. A distinction is made between contingencies at the behavioral level of analysis (contingencies of reinforcement) and contingencies at the cultural level of analysis (metacontingencies). Relations between the two kinds of contingencies are explored in cultural practices from paleolithic to industrial sociocultural systems. A synthesis of these two fields may offer the opportunity to resolve serious problems currently facing modern cultures. PMID:22478011

  13. AA.VV., Musical Networks. Parallel Distributed Perception and Performance, a cura di Niall Griffith e Peter M. Todd, MA: MIT Press, Cambridge, 1999

    Directory of Open Access Journals (Sweden)

    Maurizio Gabrieli

    2013-12-01

    Full Text Available In un periodo in cui le nuove tecnologie stanno trovando una sempre più vasta diffusione nella quasi totalità degli ambiti della produzione e della ricerca musicale, anche il settore dell'analisi musicale sembra essere coinvolto in questo lento ma inesorabile processo. Una delle ricerche più interessanti è quella che ha portato ad utilizzare, per scopi analitici, tecnologie legate alla cosiddetta Intelligenza Artificiale (IA, una disciplina nata verso la fine degli anni Cinquanta con lo scopo di simulare l'intelligenza mediante un sistema computerizzato. In mancanza di una definizione univoca di intelligenza, un primo gruppo di ricercatori del MIT (Massachusetts Institute of Tecnology, diretti da Marvin Minsksy, assunse come paradigma di riferimento l'intelligenza umana e, in una delle ricerche più avanzate nel campo, le cosiddette reti neurali (neural networks.

  14. Strategic urban governance of transition in household practices

    DEFF Research Database (Denmark)

    Quitzau, Maj-Britt; Hoffmann, Birgitte; Hansen, Trine Bang

    2013-01-01

    Several studies have indicated that urban governance is in different ways intertwined with transitions in socio-technical systems (see e.g. Bulkeley et al. 2011). For example, some local authorities attempt to gain degrees of influence and control over regimes in order to achieve territorial...... priorities (Hodson and Marvin 2010). It has been argued that such governance initiatives do seldom represent transition paths in themselves, due to the delimited focus on the urban scale (Geels 2011). However, these governance initiatives still represent important transition activities that need...... based on the work by Shove and Walker (2010), who note that practitioners are actively involved in making and reproducing socio-technical systems. We especially wish to put forward this point in relation to discussions about what role urban governance initiatives may play in transitions in socio...

  15. The changing features of the body-mind problem.

    Science.gov (United States)

    Agassi, Joseph

    2007-01-01

    The body-mind problem invites scientific study, since mental events are repeated and repeatable and invite testable explanations. They seemed troublesome because of the classical theory of substance that failed to solve its own central problems. These are soluble with the aid of the theory of the laws of nature, particularly in its emergentist version [Bunge, M., 1980. The Body-mind Problem, Pergamon, Oxford] that invites refutable explanations [Popper, K.R., 1959. The Logic of Scientific Discovery, Hutchinson, London]. The view of mental properties as emergent is a modification of the two chief classical views, materialism and dualism. As this view invites testable explanations of events of the inner world, it is better than the quasi-behaviorist view of self-awareness as computer-style self-monitoring [Minsky, M., Laske, O., 1992. A conversation with Marvin Minsky. AI Magazine 13 (3), 31-45].

  16. Panel established to revise position statement on climate change

    Science.gov (United States)

    President Robert Dickinson has appointed a panel to review the current AGU position statement on climate change and greenhouse gases, and to consider revising the statement to reflect scientific progress over the last four years. Marvin Geller of the State University of New York-Stonybrook chairs the panel.Other panel members include: Andre Berger, George Lemaître Catholic University of Louvain, Belgium; Anny Cazenave, Observatoire Midi-Pyrénées, Toulouse, France; John Christy, University of Alabama, Huntsville; Ellen Druffel, University of California, Irvine; Jack Fellows, University Consortium for Atmospheric Research, Boulder; Hiroshi Kanzawa, Nagoya University, Japan; William Schlesinger, Duke University, Durham; William (Jim) Shuttleworth, University of Arizona; Eric Sundquist, U.S. Geological Survey, Woods Hole; Richard Turco, University of California, Los Angeles; Ilana Wainer, Universidade Cidade Sao Paulo, Brazil.

  17. Book Review of: "The Social Context View of Sociology "

    Directory of Open Access Journals (Sweden)

    Kathryn Schmidt

    2008-10-01

    Full Text Available Readers seeking coherent sociological explanations for social inequality and oppression also will be disappointed in the book's content. The authors' focus on structural influences on social experiences glosses over experiences of oppression and inequality important to Marxist, feminist, and other 'conflict theory' traditions. However, The authors offer a book that will satisfy those who seek a book that is easily readable, replete with examples, and offers a coherent structurally focused overview of sociology. The authors draw on Marvin Olsen's (1968 nine layers of social organization to provide a framework for exploring major issues and institutions. The authors’ teaching experience shows in their ability to pace the material and use their model's levels of analysis to organize each chapter.

  18. Fieldwork Report for the Nucleic Acid Technology Lab

    DEFF Research Database (Denmark)

    Ramos, Juan David Hincapie

    The development of new technologies requires an understanding of the social issues technologies would confront when deployed. Such is the case of e-Science solutions like the Mini-Grid, whose future users are molecular biologists. The successful adoption of the Mini-Grid requires its design...... to account to the existing conditions of the molecular biologists. In this technical report we present the results of an initial fieldwork study of molecular biologists. We present their organization structure, their roles, their tools, their activities, and information management behaviors and collaboration...

  19. Stem cells: a plant biology perspective

    NARCIS (Netherlands)

    Scheres, B.J.G.

    2005-01-01

    A recent meeting at the Juan March Foundation in Madrid, Spain brought together plant biologists to discuss the characteristics of plant stem cells that are unique and those that are shared by stem cells from the animal kingdom

  20. 78 FR 75515 - Veterinary Feed Directive

    Science.gov (United States)

    2013-12-12

    ... professionals, such as poultry pathologists and fish health biologists. The need for greater flexibility in a... fed ``top dressed'' on (added on top of usual ration) or offered ``free-choice'' (e.g., supplement) in...

  1. The Zoogeography of North American freshwater fishes

    National Research Council Canada - National Science Library

    Hocutt, Charles H; Wiley, E. O

    1986-01-01

    .... It stresses the intimate relationship between geological changes in the landscape on fish dispersal and evolution. For biologists, geologists, and geographers actively involved in biogeography, this book serves as a valuable-and practical-reference.

  2. The Biology of blue-green algae

    National Research Council Canada - National Science Library

    Carr, Nicholas G; Whitton, B. A

    1973-01-01

    .... Their important environmental roles, their part in nitrogen fixation and the biochemistry of phototrophic metabolism are some of the attractions of blue-geen algae to an increasing number of biologists...

  3. Fouha Bay Moving Window Analysis, Benthic Quadrat Surveys at Guam in 2014

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — PIRO Fishery Biologist gathered benthic cover data using a 1m2 quadrat with 25 intersecting points every five meters along a transect running from the inner bay to...

  4. Browse Title Index

    African Journals Online (AJOL)

    Items 151 - 200 of 719 ... South American Dwarf Cichlids: A-numbers, Habitat, Care and Reproduction ... The Tilapia Trail — the life story of a fish biologist ... acid signatures indicate changes in phytobenthos composition on an artificial substrate?

  5. IDENTIFICATION OF AVIAN-SPECIFIC FECAL METAGENOMIC SEQUENCES USING GENOME FRAGMENT ENRICHMENTS

    Science.gov (United States)

    Sequence analysis of microbial genomes has provided biologists the opportunity to compare genetic differences between closely related microorganisms. While random sequencing has also been used to study natural microbial communities, metagenomic comparisons via sequencing analysis...

  6. Cloud Technology May Widen Genomic Bottleneck - TCGA

    Science.gov (United States)

    Computational biologist Dr. Ilya Shmulevich suggests that renting cloud computing power might widen the bottleneck for analyzing genomic data. Learn more about his experience with the Cloud in this TCGA in Action Case Study.

  7. John Iiames, Ph.D.

    Science.gov (United States)

    Research Biologist within the Landscape Characterization Branch at the U.S. EPA, Research Triangle Park, NC. He is the Principal Investigator for EPA MODIS LAI validation research examining the needle-leaf biome in the southeastern U.S.

  8. Site 300 Bat Monitoring Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Drennan, Joe [Garcia and Associates, San Francisco, CA (United States); Tortosa, Justin [Garcia and Associates, San Francisco, CA (United States)

    2016-07-18

    From June 15 to 18, 2015, GANDA biologist Graham Neale assisted in programming and fieldtesting of the bat monitoring equipment. The equipment was deployed in the field on a meteorological (MET) tower within Site 300 on June 18, 2015.

  9. Salmonids surveys, number of juvenile fish, fork length, and species diversity conducted in the Little Campbell Creek watershed, Alaska from 2010-11-01 to 2011-03-01 (NCEI Accession 0148761)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Over the past few years biologists and other researchers have encountered noticeable fish die-offs, mostly of young salmonid, in various stretches of Little Campbell...

  10. Small molecules: the missing link in the central dogma.

    Science.gov (United States)

    Schreiber, Stuart L

    2005-07-01

    Small molecules have critical roles at all levels of biological complexity and yet remain orphans of the central dogma. Chemical biologists, working with small molecules, expand our understanding of these central elements of life.

  11. The Influential of Physico-chemical Parameters on the Distributions ...

    African Journals Online (AJOL)

    DR. MIKE HORSFALL

    importance to aquatic biologists because they can indicate ... pollution. The changes which take place in benthic species composition with polluted conditions form the basis on ... The worms were placed in plastic bottles and were preserved ...

  12. Naturally Speaking: A Systems Biology Tool With Natural Language Interfaces

    National Research Council Canada - National Science Library

    Antoniotti, Marco; Lau, Ian T; Mishra, Bud

    2004-01-01

    .... Thus, this bioinformatics system improves the quality of the interaction that a biologist can have with a system built on rigorous mathematical modeling, but without being aware of the underlying...

  13. Coastal Wetland Restoration Bibliography

    National Research Council Canada - National Science Library

    Yozzo, David

    1997-01-01

    This bibliography was compiled to provide biologists, engineers, and planners at Corps Districts and other agencies/ institutions with a guide to the diverse body of literature on coastal wetland restoration...

  14. Lessons from Embryos: Haeckel's Embryo Drawings, Evolution, and Secondary Biology Textbooks

    Science.gov (United States)

    Wellner, Karen L.

    2014-01-01

    In 1997, developmental biologist Michael Richardson compared his research team's embryo photographs to Ernst Haeckel's 1874 embryo drawings and called Haeckel's work "noncredible". "Science" soon published "Haeckel's Embryos: Fraud Rediscovered," and Richardson's comments further reinvigorated criticism of Haeckel by…

  15. Current status and scope of coral reef research in India: A bio-ecological perspective

    Digital Repository Service at National Institute of Oceanography (India)

    De, K.; Venkataraman, K.; Ingole, B.S.

    and huge reefs India has, and all the benefits this country gets from its reefs; the efforts to manage and conserve appears poor. Review of research suggests that better management coupled with trained marine biologists, modern infrastructure facility...

  16. Fulltext PDF

    Indian Academy of Sciences (India)

    Unknown

    attitudes of plant breeders and molecular biologists towards rice. † ... plant breeding in India, who have been attempting to employ molecular biology ...... Lukes S 1974 Power: A radical view (London: Macmillan) ... tions (New York: Free Press).

  17. R-ES-ONA--NCE

    Indian Academy of Sciences (India)

    Mendel's Laws oflnheritance, heredity was still a mystery to biologists, and ... of paternal and maternal influences, the segregation of parental types in ... Genes on X and Y chromosomes, or those on mitochondrial or chloroplast DNA, are.

  18. VT Foote Brook Natural Channel Design Restoration 2001-2002

    Data.gov (United States)

    Vermont Center for Geographic Information — (Link to Metadata) The Foote Brook, located in Johnson, Vermont, is known to biologists and anglers as a high quality stream with significant natural reproduction of...

  19. VT Foote Brook Natural Channel Design Restoration 2003

    Data.gov (United States)

    Vermont Center for Geographic Information — (Link to Metadata) The Foote Brook, located in Johnson, Vermont, is known to biologists and anglers as a high quality stream with significant natural reproduction of...

  20. A Haldane Primer: Getting Messages Across

    Indian Academy of Sciences (India)

    justice to the good cause of writing text books for Indian students. ... S Krishnaswamy. Haldane was a scientist known for his contri- ... engineering and train as a biologist, I entered. RESONANCE I ... cial technical knowledge. The book is inex-.

  1. Report on the Biosphere 1976

    Science.gov (United States)

    Woodwell, George M.

    1977-01-01

    Discusses contemporary challenges for biologists, environmentalists, technologists, teachers, and political supporters of science and education in solving global problems. Discussed are nation- and worldwide accumulation of toxic materials (DDT, PCB's, kepone, radioactivity, dieldrin, mirex), transformation of natural ecosystems, and instability…

  2. Fulltext PDF

    Indian Academy of Sciences (India)

    Unknown

    stressed seedlings of an indica rice. 25. Bacillus thuringiensis. Cloning and characterization of an insecticidal crystal protein gene from Bacillus thuringiensis subspecies kenyae. 5. Bateson, William. William Bateson: a biologist ahead of his time. 49.

  3. William L Finley - Woody Vegetation Removal

    Data.gov (United States)

    Department of the Interior — The initial project was targeted for ‘hidden prairies’ along Muddy Creek. With the loss of the supervisory biologist position, the focus of this project was changed...

  4. Division of Aquatic Resources (DAR), Division of Lands and Natural Resources (DLNR) of the State of Hawaii Fish Stock Surveys from 41 sites on Oahu and Island of Hawaii from 1952-2000 (NODC Accession 0002754)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Data are from underwater visual surveys of fish stocks from 41 survey sites on the islands of Oahu and Hawaii, conducted by biologists and technicians of Hawaii's...

  5. Tsunami 2004 and the biological oceanography of Bay of Bengal

    Digital Repository Service at National Institute of Oceanography (India)

    Stephen, R.; Jayalakshmi, K.J.; Rahman, H.; Karuppasamy, P.K.; Nair, K.K.C.

    in the fishery causing public alarm. Marine Biologists are faced with environmental crisis of new complexity, properties and consequences which are to be closely monitored. PROC. NATIONAL COMMEMORATIVE CONFERENCE ON TSUNAMI. MADURAl. - 28-29, DEC, 2006 23 Fig. 1...

  6. Download this PDF file

    African Journals Online (AJOL)

    2006-12-01

    Dec 1, 2006 ... stone for human health and survival, and where conservation biologists understand that ... market conditions or local institutions do not provide them ..... maintenance and restoration of forests that protect birds, pri- mates and ...

  7. The Ecosystem Functions Model: A Tool for Restoration Planning

    National Research Council Canada - National Science Library

    Hickey, John T; Dunn, Chris N

    2004-01-01

    .... Army Corps of Engineers Hydrologic Engineering Center (HEC) is developing the EFM and envisions environmental planners, biologists, and engineers using the model to help determine whether proposed alternatives (e.g...

  8. 77 FR 27716 - Fishery of the Gulf of Mexico; Southeast Data, Assessment, and Review (SEDAR); Public Meetings

    Science.gov (United States)

    2012-05-11

    [email protected] . SUPPLEMENTARY INFORMATION: The Gulf of Mexico Fishery Management Council, in conjunction... Fishery Management Council, NOAA Fisheries Southeast Regional Office, and NOAA Southeast Fisheries Science..., biologists, and researchers; constituency representatives including fishermen, environmentalists, and NGO's...

  9. 76 FR 47563 - Fisheries of the South Atlantic; Southeast Data, Assessment, and Review (SEDAR); South Atlantic...

    Science.gov (United States)

    2011-08-05

    ... Management Councils, in conjunction with NOAA Fisheries and the Atlantic and Gulf States Marine Fisheries... Management Councils and NOAA Fisheries Southeast Regional Office and Southeast Fisheries Science Center..., biologists, and researchers; constituency representatives including fishermen, environmentalists, and NGO's...

  10. 75 FR 51983 - Fisheries of the South Atlantic and Gulf of Mexico; Southeast Data, Assessment, and Review (SEDAR...

    Science.gov (United States)

    2010-08-24

    ... INFORMATION: The Gulf of Mexico, South Atlantic, and Caribbean Fishery Management Councils, in conjunction... Caribbean Fishery Management Councils and NOAA Fisheries Southeast Regional Office and Southeast Fisheries..., biologists, and researchers; constituency representatives including fishermen, environmentalists, and NGO's...

  11. 75 FR 53951 - Fisheries of the Gulf of Mexico; Southeast Data, Assessment, and Review (SEDAR) Update; Greater...

    Science.gov (United States)

    2010-09-02

    ... Gulf of Mexico, South Atlantic, and Caribbean Fishery Management Councils, in conjunction with NOAA... Caribbean Fishery Management Councils and NOAA Fisheries Southeast Regional Office and Southeast Fisheries..., biologists, and researchers; constituency representatives including fishermen, environmentalists, and NGO's...

  12. Fish stock surveys from 41 sites on the islands of Oahu and Hawaii from September 11, 1952 to December 28, 2000 (NODC Accession 0002754)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Data are from underwater visual surveys of fish stocks from 41 survey sites on the islands of Oahu and Hawaii, conducted by biologists and technicians of Hawaii's...

  13. A Novel Pressure Indicator for Continuous Flow PCR Chip Using Micro Molded PDMS Pillar Arrays

    National Research Council Canada - National Science Library

    Zhao, Yi; Zhang, Xin

    2005-01-01

    .... Continuous flow PCR chip releases biologists from their laborious exercises. The use of such chip is, however, hindered by costly expense of the syringe pump, which is used to maintain a constant flow rate...

  14. AFSC/NMML: Bowhead whale aerial surveys and photography near Barrow, Alaska, from 1979-1992

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Bowhead whales were documented during their spring migration most years from 1979 to 1992 by biologists from NMML. This documentation consisted of flying aerial...

  15. Intellectual pursuits of Nicolas Rashevsky the queer duck of biology

    CERN Document Server

    Shmailov, Maya M

    2016-01-01

    Who was Nicolas Rashevsky? To answer that question, this book draws on Rashevsky’s unexplored personal archival papers and shares interviews with his family, students and friends, as well as discussions with biologists and mathematical biologists, to flesh out and complete the picture. “Most modern-day biologists have never heard of Rashevsky. Why?” In what constitutes the first detailed biography of theoretical physicist Nicolas Rashevsky (1899-1972), spanning key aspects of his long scientific career, the book captures Rashevsky’s ways of thinking about the place mathematical biology should have in biology and his personal struggle for the acceptance of his views. It brings to light the tension between mathematicians, theoretical physicists and biologists when it comes to the introduction of physico-mathematical tools into biology. Rashevsky’s successes and failures in his efforts to establish mathematical biology as a subfield of biology provide an important test case for understanding the role o...

  16. Small mammal trapping in tropical montane forests of the Upper ...

    Indian Academy of Sciences (India)

    Animal biologists are interested in the population size of animals, whether they are ... heterogeneity can cause substantial bias in the estimators. (Burnham and ...... diversity, extinction rates and speciation rates from fossil data using capture ...

  17. WormBase

    Data.gov (United States)

    U.S. Department of Health & Human Services — WormBase is an international consortium of biologists and computer scientists dedicated to providing the research community with accurate, current, accessible...

  18. Bottomland Hardwood Planting: Example Contract Specifications

    National Research Council Canada - National Science Library

    Humprey, Monica

    2002-01-01

    This technical note provides an example of contract specifications that can be used as a template by USACE biologists, engineers, or contracting officers for contracting the planting of bottomland hardwood (BLH) seedlings...

  19. Diversity in auxology: between theory and practice

    DEFF Research Database (Denmark)

    Hermanussen, M.; Lieberman, L. S.; Janewa, V. S.

    2012-01-01

    Auxology has developed from mere describing child and adolescent growth into a vivid and interdisciplinary research area encompassing human biologists, physicians, social scientists, economists and biostatisticians. The meeting illustrated the diversity in auxology, with the various social, medic...

  20. Biological assessment of marine resources for the Republic of the Maldives, Indian Ocean, August, 2001 (NODC Accession 0000670)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — In August 2001, biologists from the U.S. Fish and Wildlife Service and the National Marine Fisheries Service were asked to conduct an assessment of the national...

  1. An efficient and extensible approach for compressing phylogenetic trees

    KAUST Repository

    Matthews, Suzanne J; Williams, Tiffani L

    2011-01-01

    Background: Biologists require new algorithms to efficiently compress and store their large collections of phylogenetic trees. Our previous work showed that TreeZip is a promising approach for compressing phylogenetic trees. In this paper, we extend

  2. The role of theory in advancing 21st-century biology: catalyzing transformative research

    National Research Council Canada - National Science Library

    Committee on Defining and Advancing the Conceptual Basis of Biological Sciences in the 21st Century, National Research Council

    2008-01-01

    .... Biologists' theoretical and conceptual frameworks inform every step of their research, affecting what experiments they do, what techniques and technologies they develop and use, and how they interpret their data...

  3. 76 FR 26751 - Prime Hook National Wildlife Refuge, Sussex County, DE; Comprehensive Conservation Plan and...

    Science.gov (United States)

    2011-05-09

    ... suggestions for the future management of Prime Hook NWR. We previously published a notice of intent on October... challenging to wildlife managers and biologists. Mosquitoes are a part of the natural environment and a food...

  4. Guidelines for sampling fish in inland waters

    National Research Council Canada - National Science Library

    Backiel, Tadeusz; Welcomme, R. L

    1980-01-01

    The book is addressed mainly to Fishery Biologists but it is hoped that Fishing Gear Technologists also can acquire some basic knowledge of sampling problems and procedures which, in turn, can result...

  5. Redefining plant systems biology: from cell to ecosystem

    NARCIS (Netherlands)

    Keurentjes, J.J.B.; Angenent, G.C.; Dicke, M.; Martins Dos Santos, V.A.P.; Molenaar, J.; Van der Putten, W.H.; de Ruiter, P.C.; Struik, P.C.; Thomma, B.P.H.J.

    2011-01-01

    Molecular biologists typically restrict systems biology to cellular levels. By contrast, ecologists define biological systems as communities of interacting individuals at different trophic levels that process energy, nutrient and information flows. Modern plant breeding needs to increase

  6. Branching processes in biology

    CERN Document Server

    Kimmel, Marek

    2015-01-01

    This book provides a theoretical background of branching processes and discusses their biological applications. Branching processes are a well-developed and powerful set of tools in the field of applied probability. The range of applications considered includes molecular biology, cellular biology, human evolution and medicine. The branching processes discussed include Galton-Watson, Markov, Bellman-Harris, Multitype, and General Processes. As an aid to understanding specific examples, two introductory chapters, and two glossaries are included that provide background material in mathematics and in biology. The book will be of interest to scientists who work in quantitative modeling of biological systems, particularly probabilists, mathematical biologists, biostatisticians, cell biologists, molecular biologists, and bioinformaticians. The authors are a mathematician and cell biologist who have collaborated for more than a decade in the field of branching processes in biology for this new edition. This second ex...

  7. Heartbreak hotel: a convergence in cardiac regeneration.

    Science.gov (United States)

    Schneider, Michael D

    2016-05-01

    In February 2016, The Company of Biologists hosted an intimate gathering of leading international researchers at the forefront of experimental cardiovascular regeneration, with its emphasis on 'Transdifferentiation and Tissue Plasticity in Cardiovascular Rejuvenation'. As I review here, participants at the workshop revealed how understanding cardiac growth and lineage decisions at their most fundamental level has transformed the strategies in hand that presently energize the prospects for human heart repair. © 2016. Published by The Company of Biologists Ltd.

  8. Advances in stem cells and regenerative medicine: single-cell dynamics, new models and translational perspectives.

    Science.gov (United States)

    Twigger, Alecia-Jane; Scheel, Christina H

    2017-09-01

    An international cohort of over 300 stem cell biologists came together in Heidelberg, Germany in May 2017 as delegates of the 'Advances in Stem Cells and Regenerative Medicine' conference run through the European Molecular Biology Organization. This Meeting Review highlights the novel insights into stem cell regulation, new technologies aiding in discovery and exciting breakthroughs in the field of regenerative medicine that emerged from the meeting. © 2017. Published by The Company of Biologists Ltd.

  9. From stem cells to human development: a distinctly human perspective on early embryology, cellular differentiation and translational research.

    Science.gov (United States)

    Craft, April M; Johnson, Matthew

    2017-01-01

    Over 100 scientists with common interests in human development, disease and regeneration gathered in late September 2016 for The Company of Biologists' second 'From Stem Cells to Human Development' meeting held in historic Southbridge. In this Meeting Review, we highlight some of the exciting new findings that were presented, and discuss emerging themes and convergences in human development and disease that arose during these discussions. © 2017. Published by The Company of Biologists Ltd.

  10. VisRseq: R-based visual framework for analysis of sequencing data

    OpenAIRE

    Younesy, Hamid; Möller, Torsten; Lorincz, Matthew C; Karimi, Mohammad M; Jones, Steven JM

    2015-01-01

    Background Several tools have been developed to enable biologists to perform initial browsing and exploration of sequencing data. However the computational tool set for further analyses often requires significant computational expertise to use and many of the biologists with the knowledge needed to interpret these data must rely on programming experts. Results We present VisRseq, a framework for analysis of sequencing datasets that provides a computationally rich and accessible framework for ...

  11. Pep-3D-Search: a method for B-cell epitope prediction based on mimotope analysis

    OpenAIRE

    Huang, Yan Xin; Bao, Yong Li; Guo, Shu Yan; Wang, Yan; Zhou, Chun Guang; Li, Yu Xin

    2008-01-01

    Abstract Background The prediction of conformational B-cell epitopes is one of the most important goals in immunoinformatics. The solution to this problem, even if approximate, would help in designing experiments to precisely map the residues of interaction between an antigen and an antibody. Consequently, this area of research has received considerable attention from immunologists, structural biologists and computational biologists. Phage-displayed random peptide libraries are powerful tools...

  12. WE-G-213-01: Roentgen and the Birth of Modern Medical Physics

    Energy Technology Data Exchange (ETDEWEB)

    Sprawls, P. [Sprawls Educational Foundation (United States)

    2015-06-15

    Roentgen and the Birth of Modern Medical Physics – Perry Sprawls Wilhelm Roentgen is well known for his discovery of x-radiation. What is less known and appreciated is his intensive research following the discovery to determine the characteristics of the “new kind of radiation” and demonstrate its great value for medical purposes. In this presentation we will imagine ourselves in Roentgen’s mind and follow his thinking, including questions and doubts, as he designs and conducts a series of innovative experiments that provided the foundation for the rapid growth of medical physics. Learning Objectives: Become familiar with the personal characteristics and work of Prof. Roentgen that establishes him as an inspiring model for the medical physics profession. Observe the thought process and experiments that determined and demonstrated the comprehensive characteristics of x-radiation. The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who were they and what did they do? – Lawrence N. Rothenberg William David Coolidge (1873–1975) William Coolidge was born in Hudson, NY in 1873. He obtained his BS at the Massacusetts Institute of Technology in 1896. Coolidge then went to the University of Leipzig, Germany for graduate study with physicists Paul Drude and Gustave Wiedemann and received a Ph.D. in 1899. While in Germany he met Wilhelm Roentgen. Coolidge returned to the US to teach at MIT where he was associated with Arthur A. Noyes of the Chemistry Department, working on the electrical conductivity of aqueous solutions. Willis R. Whitney, under whom Coolidge had worked before going to Germany, became head of the newly formed General Electric Research Laboratory and he invited Coolidge to work with him. In 1905, Coolidge joined the staff of the GE laboratory and was associated with it for the remainder of his life. He developed ductile tungsten filaments to replace fragile carbon filaments as the material for electric light

  13. WE-G-213-01: Roentgen and the Birth of Modern Medical Physics

    International Nuclear Information System (INIS)

    Sprawls, P.

    2015-01-01

    Roentgen and the Birth of Modern Medical Physics – Perry Sprawls Wilhelm Roentgen is well known for his discovery of x-radiation. What is less known and appreciated is his intensive research following the discovery to determine the characteristics of the “new kind of radiation” and demonstrate its great value for medical purposes. In this presentation we will imagine ourselves in Roentgen’s mind and follow his thinking, including questions and doubts, as he designs and conducts a series of innovative experiments that provided the foundation for the rapid growth of medical physics. Learning Objectives: Become familiar with the personal characteristics and work of Prof. Roentgen that establishes him as an inspiring model for the medical physics profession. Observe the thought process and experiments that determined and demonstrated the comprehensive characteristics of x-radiation. The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who were they and what did they do? – Lawrence N. Rothenberg William David Coolidge (1873–1975) William Coolidge was born in Hudson, NY in 1873. He obtained his BS at the Massacusetts Institute of Technology in 1896. Coolidge then went to the University of Leipzig, Germany for graduate study with physicists Paul Drude and Gustave Wiedemann and received a Ph.D. in 1899. While in Germany he met Wilhelm Roentgen. Coolidge returned to the US to teach at MIT where he was associated with Arthur A. Noyes of the Chemistry Department, working on the electrical conductivity of aqueous solutions. Willis R. Whitney, under whom Coolidge had worked before going to Germany, became head of the newly formed General Electric Research Laboratory and he invited Coolidge to work with him. In 1905, Coolidge joined the staff of the GE laboratory and was associated with it for the remainder of his life. He developed ductile tungsten filaments to replace fragile carbon filaments as the material for electric light

  14. The Meteoritical Quincentennial: The Stone of Ensisheim 1492-1992

    Science.gov (United States)

    Marvin, U. B.

    1992-07-01

    This year marks the 500th anniversary of the fall of a meteorite at Ensisheim in Alsace. In at least two respects this event is unique in the history of meteoritics. First, this was the earliest witnessed meteorite fall in the West from which pieces are preserved. Second, it is the only meteorite of which a continuous five-century public record exists in manuscripts and books. Beginning with newsheets printed in 1492, writings about this event illuminate the evolution of ideas from a 15th century belief that stones from the sky were of miraculous origin, to an 18th century conviction that stones do not fall from the sky, to our present view that they fall in abundance, originating in interplanetary space (Marvin, 1992). This paper will highlight certain previously unexamined aspects of the story and address problems inherent in historical analysis. Unusable Maps. The fall of the stone was heralded by an explosion which, according to Sebastian Brant (1492), was heard along the valleys of the Danube, Neckar, Aare, Ill, and Rhine and in the alpine cantons of Schwyz and Uri. Contemporary maps, such as that published in The Nuremberg Chronicle of 1493, so distorted the regional geography that a fireball trajectory cannot be reconstructed on them. On modern maps, however, the areas Brant listed stretch about 150 km to the southeast of Ensisheim, a distance well within the range of sounds reported from other exploding fireballs. Newton (1891) and Marvin (1992) worked out possible trajectories that could account for the sound being heard in all named localities. This suggests that, far from exaggerating distances for dramatic effect, Brant's description may well have been accurate. If so, he compiled his information from word-of-mouth reports without reference to the rudimentary maps available in his time. The Language of Wonder. A document mounted beside the stone in the Ensisheim church stated that learned men did not know what it was: it must be supernatural, a wonder

  15. Estudo e determinação teórica de propriedades físico-químicas de fármacos anti-hipertensivos inibidores da Enzima Conversora de Angiotensina

    Directory of Open Access Journals (Sweden)

    LUíZA REIS CRUZ

    2010-12-01

    Full Text Available O pacote de softwares SpartanTM vs 04 foi utilizado para calcular algumas propriedades físico-químicas de uma série de inibidores da Enzima Conversora de Angiotensinogênio ECA. Simultaneamente, o pacote MarvinSketch 5.0.0 foi empregado para calcular o Coeficiente de Partição P dos inibidores. Através da análise dos resultados, conclui-se que: a o arranjo termodinâmico mais estável desses inibidores mimetiza aquele dos resíduos pré-terminais da angiotensina II, b há grande similaridade entre as cargas dos átomos que se ligam à macromolécula e c os cálculos mostram diferenças significativas entre os valores de P para os inibidores. Portanto, as diferenças farmacológicas existentes entre os inibidores estão mais intimamente relacionadas ao coeficiente de partição do que à capacidade destes de inibir o sítio ativo da ECA. Palavras-chave: ECA. Ab initio. Equilíbrio conformacional. Lipofilicidade. ABSTRACT Theoretical study and determination of physicochemical properties of antihypertensive angiotensin-converting enzyme inhibitors The software package SpartanTM 4.0 was employed to calculate some physicochemical properties of a series of available ACE inhibitors. Simultaneously, the program MarvinSketch 5.0.0 was employed to calculate the partition coefficients (P of the same compounds. After analyzing the results, we conclude that: a from a thermodynamic point of view, the most stable conformer of each inhibitor resembles, as expected, the most stable spatial arrangement of the preterminal residues of angiotensin II; b there is great similarity among the charge profiles of the potential binding sites of all the inhibitors; c there are large differences in P among these compounds. Summing up, the pharmacological differences reported between the inhibitors are more closely linked to their lipophilic properties than to their capacity to block the ACE active center. Keywords: ACE. Ab initio. Conformational

  16. Ontologies and standards in bioscience research: for machine or for human

    Directory of Open Access Journals (Sweden)

    Huaiyu eMi

    2011-02-01

    Full Text Available Ontologies and standards are very important parts of today’s bioscience research. With the rapid increase of biological knowledge, they provide mechanisms to better store and represent data in a controlled and structured way, so that scientists can share the data, and utilize a wide variety of software and tools to manage and analyze the data. Most of these standards are initially designed for computers to access large amounts of data that are difficult for human biologists to handle, and it is important to keep in mind that ultimately biologists are going to produce and interpret the data. While ontologies and standards must follow strict semantic rules that may not be familiar to biologists, effort must be spent to lower the learning barrier by involving biologists in the process of development, and by providing software and tool support. A standard will not succeed without support from the wider bioscience research community. Thus, it is crucial that these standards be designed not only for machines to read, but also to be scientifically accurate and intuitive to human biologists.

  17. Directory of Open Access Journals (Sweden)

    M Yavuz Coşkun

    2011-06-01

    Full Text Available Andrejs Geske University of Latvia, Latvia B. N.Ghosh (Eastern Med.Univ. North Cyprus Bayram Ürekli (University of Selçuk, Türkiye Erdinç Didar (American University, Bulgaria Ercan Tatlıdil (University of Ege, Türkiye Erman Artun (University of Çukurova, Türkiye Hikmet Y.Celkan (University of Gaziantep, Türkiye Hüseyin Bağcı (METU, Türkiye Jean Crombois (American University, Bulgaria Kemal Silay (Indiana University, USA Lelio Iapadre (University of L'Aquila, Italy Michael Goldman (University of Minnesota, USA Bilgehan Pamuk (University of Gaziantep, Türkiye

  18. AJ26 rocket engine testing news briefing

    Science.gov (United States)

    2010-01-01

    NASA's John C. Stennis Space Center Director Gene Goldman (center) stands in front of a 'pathfinder' rocket engine with Orbital Sciences Corp. President and Chief Operating Officer J.R. Thompson (left) and Aerojet President Scott Seymour during a Feb. 24 news briefing at the south Mississippi facility. The leaders appeared together to announce a partnership for testing Aerojet AJ26 rocket engines at Stennis. The engines will be used to power Orbital's Taurus II space vehicles to provide commercial cargo transportation missions to the International Space Station for NASA. During the event, the Stennis partnership with Orbital was cited as an example of the new direction of NASA to work with commercial interests for space travel and transport.

  19. Elementary Particles and the Universe

    Science.gov (United States)

    Schwarz, John H.

    2005-07-01

    1. Excess baggage J. Hartle; 2. Through the clouds E. Witten; 3. Covariant foundations of the superparticle L. Brink; 4. Chiral symmetry and confinement T. Goldman; 5. The original fifth interaction Y. Neeman; 6. The mass hierarchy of leptons and quarks H. Fritzsch; 7. Spacetime duality in string theory J. H. Schwarz; 8. Symmetry and quasi-symmetry Y. Nambu; 9. On an exceptional non-associative superspace M. Gunaydin; 10. Algebra of reparametrization-invariant and normal ordered operators in open string field theory P. Ramond; 11. Superconductivity of an ideal charged boson system T. D. Lee; 12. Some remarks on the symmetry approach to nuclear rotational motion L. C. Biedebharn and P. Truini; 13. Uncomputability, intractability and the efficiency of heat engines S. Lloyd; 14. The new mathematical physics I. Singer; 15. For the birds V. Telegdi; 16. Gell-Mann's approach to physics A. Salam; 17. Remarks M. Goldberger.

  20. Integration of auditory and visual communication information in the primate ventrolateral prefrontal cortex.

    Science.gov (United States)

    Sugihara, Tadashi; Diltz, Mark D; Averbeck, Bruno B; Romanski, Lizabeth M

    2006-10-25

    The integration of auditory and visual stimuli is crucial for recognizing objects, communicating effectively, and navigating through our complex world. Although the frontal lobes are involved in memory, communication, and language, there has been no evidence that the integration of communication information occurs at the single-cell level in the frontal lobes. Here, we show that neurons in the macaque ventrolateral prefrontal cortex (VLPFC) integrate audiovisual communication stimuli. The multisensory interactions included both enhancement and suppression of a predominantly auditory or a predominantly visual response, although multisensory suppression was the more common mode of response. The multisensory neurons were distributed across the VLPFC and within previously identified unimodal auditory and visual regions (O'Scalaidhe et al., 1997; Romanski and Goldman-Rakic, 2002). Thus, our study demonstrates, for the first time, that single prefrontal neurons integrate communication information from the auditory and visual domains, suggesting that these neurons are an important node in the cortical network responsible for communication.

  1. Toward the development of a rational scale in the use of human-figure drawings as a kindergarten screening measure.

    Science.gov (United States)

    Goldman, R K; Velasco, M M

    1980-04-01

    The Draw-A-Person Test was individually administered to 120 kindergartners from diverse socioeconomic backgrounds, ranging in age from 4 yr. and 10 mo. to 6 yr. and 4 mo. This study was conducted to validate and expand Goldman and Warren's earlier work (1976) on the development of a rational scale for use as a kindergarten screening measure. Correlational analyses corroborate the earlier findings that body-part omissions are the most predictive items of emotional high risk. Factor analyses of the current data also replicate earlier findings in which two underlying cohesive factors emerged. The first factor has high loadings on peripheral body-part omissions; the second factor has high loadings on central body-part omission. The results suggest that an interchangeable number of body-part omissions together, rather than any one item, predict high emotional risk. Structural and content characteristics do not contribute significantly to the development of a kindergarten screening measure.

  2. Total internal partition sums for molecular species in the 2000 edition of the HITRAN database

    International Nuclear Information System (INIS)

    Fischer, J.; Gamache, R.R.; Goldman, A.; Rothman, L.S.; Perrin, A.

    2003-01-01

    Total internal partition sums (TIPS) are calculated for all molecular species in the 2000 HITRAN database. In addition, the TIPS for 13 other isotopomers/isotopologues of ozone and carbon dioxide are presented. The calculations address the corrections suggested by Goldman et al. (JQSRT 66 (2000) 455). The calculations consider the temperature range 70-3000 K to be applicable to a variety of remote sensing needs. The method of calculation for each molecular species is stated and comparisons with data from the literature are discussed. A new method of recall for the partition sums, Lagrange 4-point interpolation, is developed. This method, unlike previous versions of the TIPS code, allows all molecular species to be considered

  3. A new species of nectar-feeding bat, genus Lonchophylla, from western Colombia and western Ecuador (Mammalia: Chiroptera: Phyllostomidae)

    Science.gov (United States)

    Woodman, N.

    2007-01-01

    The twelve recognized species of nectar-feeding bats of the genus Lonchophylla occur in low- and middle-elevation, humid, Neotropical forests. Morphological and morphometrical analyses of specimens formerly lumped with Lonchophylla mordax O. Thomas (1903) support recognition of Lonchophylla concava Goldman (1914) as a separate species and reveal a third species from the western Pacific lowlands of Colombia and Ecuador that I describe herein as Lonchophylla jornicata. This new species is morphologically similar to Lonchophylla concava but is distinctively larger than that species. Tests for sexual dimorphism within these and other species of Lonchophyllini suggest a tendency for females to have slightly longer, narrower skulls, higher coronoid processes of the mandible, and longer forearms than males.

  4. Counterfactual reasoning for regretted situations involving controllable versus uncontrollable events: the modulating role of contingent self-esteem.

    Science.gov (United States)

    Wilkinson, Meredith R; Ball, Linden J; Alford, David

    2015-01-01

    We report a study that examined the modulating impact of contingent self-esteem on regret intensity for regretted outcomes associated with controllable versus uncontrollable events. The Contingent Self-Esteem Scale (e.g., Kernis & Goldman, 2006) was used to assess the extent to which a person's sense of self-worth is based on self and others' expectations. We found that there was an influence of self-esteem contingency for controllable but not for uncontrollable regret types. For controllable regret types individuals with a high contingent (i.e., unstable) self-esteem reported greater regret intensity than those with a low contingent (i.e., stable) self-esteem. We interpret this finding as reflecting a functional and adaptive role of high contingent self-esteem in terms of mobilizing the application of counterfactual reasoning and planning mechanisms that can enable personal expectations to be achieved in the future.

  5. Degargūnī-ye ejtem‘ī va fīlm-hā-ye sīnemā’ī dar Īrān : jāme‘e-šenāsī-ye fīlm-hā-ye ‘āmme-pasand-e īrānī (1309-1357) [Social Change and Iranian Motion Picture: Sociology of Popular Films (1920-1978)]. Tehrān, Entešārāt-e Far

    OpenAIRE

    Rafii Nejad, Poupak

    2008-01-01

    Le cinéma iranien (de ses débuts jusqu’avant la révolution) est l’objet d’étude de cet ouvrage, d’un point de vue sociologique. L’A. ne s’intéresse pas aux aspects esthétique, moral, éducatif ou artistique des films, mais à leur aspect représentatif. Il énonce ses sources théoriques (l’école de Francfort, L. Goldman, A. Asaberger, etc.) concernant d’une part l’analyse statique (structurelle) des thèmes traités par les films et leur interprétation et d’autre part une analyse dynamique des indi...

  6. Counterfactual Reasoning for Regretted Situations Involving Controllable Versus Uncontrollable Events: The Modulating Role of Contingent Self-Esteem

    Science.gov (United States)

    Wilkinson, Meredith R.; Ball, Linden J.; Alford, David

    2015-01-01

    We report a study that examined the modulating impact of contingent self-esteem on regret intensity for regretted outcomes associated with controllable versus uncontrollable events. The Contingent Self-Esteem Scale (e.g., Kernis & Goldman, 2006) was used to assess the extent to which a person’s sense of self-worth is based on self and others’ expectations. We found that there was an influence of self-esteem contingency for controllable but not for uncontrollable regret types. For controllable regret types individuals with a high contingent (i.e., unstable) self-esteem reported greater regret intensity than those with a low contingent (i.e., stable) self-esteem. We interpret this finding as reflecting a functional and adaptive role of high contingent self-esteem in terms of mobilizing the application of counterfactual reasoning and planning mechanisms that can enable personal expectations to be achieved in the future. PMID:25883697

  7. INTERRELATIONSHIP BETWEEN TEMPERATURE AND SODIUM CHLORIDE ON GROWTH OF LACTIC ACID BACTERIA ISOLATED FROM MEAT-CURING BRINES.

    Science.gov (United States)

    GOLDMAN, M; DEIBEL, R H; NIVEN, C F

    1963-05-01

    Goldman, Manuel (American Meat Institute Foundation, Chicago, Ill.), R. H. Deibel, and C. F. Niven, Jr. Interrelationship between temperature and sodium chloride on growth of lactic acid bacteria isolated from meat-curing brines. J. Bacteriol. 85:1017-1021. 1963.-An elevation of the temperature limit for growth of some Pediococcus homari (Gaffkya homari) and motile Lactobacillus strains could be effected by the addition of sodium chloride to the growth medium. At the optimal temperature for growth, sodium chloride was stimulatory, and as the temperature of incubation was increased a mandatory requirement for sodium chloride was manifested. At the optimal temperature for growth (30 C), the highest sodium chloride concentrations were tolerated; as the temperature was increased, this tolerance decreased, although the optimal sodium chloride concentration increased. No other substances were found that would replace the sodium chloride requirement at higher temperatures of incubation.

  8. Role of nuclear energy in environment, economy, and energy issues of the 21st century. Growing energy demand in Asia and role of nuclear

    International Nuclear Information System (INIS)

    Tashimo, Masanori; Matsui, Kazuaki

    2008-01-01

    The economic growth of recent Asia is rapid, and the GDP and the energy consumption growth rate are about 8-10% in China and India. The energy consumption forecast of Asia in this century was estimated based on the GDP growth rate by Goldman Sachs. As a result, about twice in India and Association of South East Asian Nations (ASEAN) and about 1.5 times in China of SRES B (Special Report on Emission Scenarios) are forecasted. The simulation was done by Grape Code to analyze the impact of energy increase in Asia. As for the nuclear plant in Asia, it is expected 1500 GWe in 2050 and 2000 GWe in 2100, in the case of the environmental constrain. To achieve this nuclear utilization, there are two important aspects, technically and institutionally. (author)

  9. A comparison of four measures of moral reasoning.

    Science.gov (United States)

    Wilmoth, G H; McFarland, S G

    1977-08-01

    Kohlberg's Moral Judgment Scale, Gilligan et al.'s Sexual Moral Judgment Scale, Maitland and Goldman's Objective Moral Judgment Scale, and Hogan's Maturity of Moral Judgment Scale, were examined for reliability and inter-scale relationships. All measures except the Objective Moral Judgment Scale had good reliabilities. The obtained relations between the Moral Judgment Scale and the Sexual Moral Judgment Scale replicated previous research. The Objective Moral Judgment Scale was not found to validly assess the Kohlberg stages. The Maturity of Moral Judgment Scale scores were strongly related to the subjects's classification on the Kohlberg stages, and the scale appears to offer a reliable, quickly scored, and valid index of mature thought, although the scale's continuous scores do not permit clear stage classification.

  10. Ups and downs of alcohol use among first-year college students: Number of drinks, heavy drinking, and stumble and pass out drinking days.

    Science.gov (United States)

    Maggs, Jennifer L; Williams, Lela Rankin; Lee, Christine M

    2011-03-01

    Given the dynamic fluctuating nature of alcohol use among emerging adults (Del Boca, Darkes, Greenbaum, & Goldman, 2004), patterns of alcohol use were modeled across 70 days in an intensive repeated-measures diary design. Two hundred first-year college students provided 10 weekly reports of their daily alcohol consumption via computer-assisted telephone interviews. Multi-level models demonstrated large within-person variability across days in drinks consumed, binge drinking, and days exceeding self-reported limits for stumbling around and passing out; these outcome variables were predicted by weekdays vs. weekend days (within-person) and gender, age of drinking initiation, fraternity/sorority membership, and alcohol motivations (between-persons). Repeated measurement of alternate indicators of alcohol use permits the examination of novel and important questions about alcohol use and abuse particularly in young adult and other erratically drinking populations. Copyright © 2010 Elsevier Ltd. All rights reserved.

  11. Motion of cells sedimenting on a solid surface in a laminar shear flow.

    Science.gov (United States)

    Tissot, O; Pierres, A; Foa, C; Delaage, M; Bongrand, P

    1992-01-01

    Cell adhesion often occurs under dynamic conditions, as in flowing blood. A quantitative understanding of this process requires accurate knowledge of the topographical relationships between the cell membrane and potentially adhesive surfaces. This report describes an experimental study made on both the translational and rotational velocities of leukocytes sedimenting of a flat surface under laminar shear flow. The main conclusions are as follows: (a) Cells move close to the wall with constant velocity for several tens of seconds. (b) The numerical values of translational and rotational velocities are inconsistent with Goldman's model of a neutrally buoyant sphere in a laminar shear flow, unless a drag force corresponding to contact friction between cells and the chamber floor is added. The phenomenological friction coefficient was 7.4 millinewton.s/m. (c) Using a modified Goldman's theory, the width of the gap separating cells (6 microns radius) from the chamber floor was estimated at 1.4 micron. (d) It is shown that a high value of the cell-to-substrate gap may be accounted for by the presence of cell surface protrusions of a few micrometer length, in accordance with electron microscope observations performed on the same cell population. (e) In association with previously reported data (Tissot, O., C. Foa, C. Capo, H. Brailly, M. Delaage, and P. Bongrand. 1991. Biocolloids and Biosurfaces. In press), these results are consistent with the possibility that cell-substrate attachment be initiated by the formation of a single molecular bond, which might be considered as the rate limiting step.

  12. Etnografia como prática e experiência

    Directory of Open Access Journals (Sweden)

    José Guilherme Cantor Magnani

    2009-12-01

    Full Text Available Este artigo, a partir de alguns usos pouco ortodoxos da etnografia, fora do campo da antropologia, propõe uma discussão sobre a especificidade desse método de pesquisa, com base em pesquisas e reflexões realizadas sobre o tema no Núcleo de Antropologia Urbana da USP (NAU. Tomando como ponto de partida uma citação de Lévi-Strauss, repassa alguns autores - Goldman, Peirano, DaMatta, Favret-Saada, entre outros - para estabelecer parâmetros na busca de traços que considera específicos do fazer etnográfico e assim chega a três considerações principais: etnografia como experiência, como prática e com base numa certa noção de totalidade. O relato de uma etnografia sobre jovens surdos é apresentado para oferecer um suporte empírico àquelas conclusões.Considering some less orthodox uses of ethnography, not belonging to the anthropological field, this article proposes a discussion on the specificities of the ethnographical research method, based on reflections and researches undertaken at the Urban Anthropology Nucleus (NAU. Taking a Lévi-Strauss's quotation as its starting point, it examines the ideas of authors like Goldman, Peirano, Da Matta, Favret-Saada, among others, in order to establish parameters to guide the search for specific features in the ethnographic métier. Such a discussion leads to three considerations: ethnography as experience, as practice, and as based on a certain concept of "totality". The report of an ethnography on deaf young people is included in the article as empirical support to the conclusions.

  13. The effects of intravenous aminoacid infusion on myocardial functions and postoperative analgesia during abdominal aortic surgery

    Directory of Open Access Journals (Sweden)

    Mustafa Turhan

    2013-03-01

    Full Text Available Objective: Effects of intravenous aminoacid infusion onmyocardial functions and postoperative analgesia in abdominalaortic surgery were investigated.Materials and methods: Forty patients were randomlydivided into groups of general anaesthesia with or withoutaminoacid infusion (Group 1 and 2, n=10, combinedgeneral+epidural with or without amino acid infusion (Group3 and 4, n=10. Cardiac risk was evaluated using 2007 AHA/ACC and modified Goldman classifications. Intravenousaminoacid solution of 80 g/L was infused at 2.5 ml/kg/h for atotal of 8 hours. General anaesthesia included intravenousremifentanil, rocuronium, sevoflurane. The lumbar epiduralinclude; 10 mL of 0.25% bupivacaine; bolus dose, an infusionof 0.25% bupivacaine; 4 ml/h for 24 hours. Heart rate,arterial blood pressures were collected intraoperative every10 minute, 1, 24 hour postoperatively. Plasma creatinekinase MB fraction, troponin levels, pain assessment withnumeric analog scale were collected preoperatively, 1, 24hour postoperatively. Postoperative 24 hour analgesic usage,complications were recorded.Results: Patients with mild and severe cardiac risk werehigher in 2007 AHA/ACC classification (26/40, 65% thanmodified Goldman risk classification (5/40, 12.5% (p=0.04.In comparison between groups, myocardial enzyme levelsand complications showed no difference (p>0.05. The useof analgesics were lower in group 3 and 4 in comparison togroup 1 and 2 (p=0.002.Conclusion: During abdominal aortic surgery, intravenousinfusion of amino acid did not show significant changes onintraoperative and postoperative hemodynamic parametersand myocardial enzymes. The patients received combinedgeneral plus epidural anaesthesia showed more successfulpostoperative analgesia.Key words: Amino acid, abdominal aorta, vascular surgery,epidural anesthesia, general anesthesia, keratin kinase,troponin, postoperative analgesia

  14. E-evolution : e-commerce spread, bu e-dustrial revolution is on hold

    International Nuclear Information System (INIS)

    Lunan, D.

    2001-01-01

    Approximately two years ago, e-commerce seemed ready to revolutionize the way the oil and gas industry conducted business. After the dot-com demise, Statistics Canada reported that less than one per cent of resource sector companies were selling goods on the Internet. According to financial industry experts, the energy industry should implement an e-business strategy based on four major concepts. They recommended using the Internet as a procurement source, the idea easiest to implement and with the potential to positively improve the bottom line. The second area recommended was assets acquisition and disposition. Some portals have already targeted this market niche, such as IndigoPool.com, operated by Schlumberger. In addition to assets, the portal offers millions of kilometres of two-dimensional seismic data, as well as three-dimensional and gravity or magnetic surveys. Portals like IndigoPool also feature electronic data rooms, similar to physical data rooms where registered customers can view and analyze all relevant information. A key partner in IndigoPool is Waterhouse and Co., whose responsibility is the handling of bids for various properties in Western Canada. The third aspect recommended by Goldman Sachs in a report, is trading in a number of commodities like natural gas, crude oil and liquids, electricity, etc. The fourth aspect favored by Goldman Sachs is reporting and regulatory filings. The National Energy Board established a phased-in electronic regulatory filing environment in the spring of 2001. The standardization of industry and government information systems is continuing on an international scale. 5 figs

  15. E-evolution : e-commerce spread, bu e-dustrial revolution is on hold

    Energy Technology Data Exchange (ETDEWEB)

    Lunan, D.

    2001-09-03

    Approximately two years ago, e-commerce seemed ready to revolutionize the way the oil and gas industry conducted business. After the dot-com demise, Statistics Canada reported that less than one per cent of resource sector companies were selling goods on the Internet. According to financial industry experts, the energy industry should implement an e-business strategy based on four major concepts. They recommended using the Internet as a procurement source, the idea easiest to implement and with the potential to positively improve the bottom line. The second area recommended was assets acquisition and disposition. Some portals have already targeted this market niche, such as IndigoPool.com, operated by Schlumberger. In addition to assets, the portal offers millions of kilometres of two-dimensional seismic data, as well as three-dimensional and gravity or magnetic surveys. Portals like IndigoPool also feature electronic data rooms, similar to physical data rooms where registered customers can view and analyze all relevant information. A key partner in IndigoPool is Waterhouse and Co., whose responsibility is the handling of bids for various properties in Western Canada. The third aspect recommended by Goldman Sachs in a report, is trading in a number of commodities like natural gas, crude oil and liquids, electricity, etc. The fourth aspect favored by Goldman Sachs is reporting and regulatory filings. The National Energy Board established a phased-in electronic regulatory filing environment in the spring of 2001. The standardization of industry and government information systems is continuing on an international scale. 5 figs.

  16. The Virtual Cell: a software environment for computational cell biology.

    Science.gov (United States)

    Loew, L M; Schaff, J C

    2001-10-01

    The newly emerging field of computational cell biology requires software tools that address the needs of a broad community of scientists. Cell biological processes are controlled by an interacting set of biochemical and electrophysiological events that are distributed within complex cellular structures. Computational modeling is familiar to researchers in fields such as molecular structure, neurobiology and metabolic pathway engineering, and is rapidly emerging in the area of gene expression. Although some of these established modeling approaches can be adapted to address problems of interest to cell biologists, relatively few software development efforts have been directed at the field as a whole. The Virtual Cell is a computational environment designed for cell biologists as well as for mathematical biologists and bioengineers. It serves to aid the construction of cell biological models and the generation of simulations from them. The system enables the formulation of both compartmental and spatial models, the latter with either idealized or experimentally derived geometries of one, two or three dimensions.

  17. Organic chemistry and biology: chemical biology through the eyes of collaboration.

    Science.gov (United States)

    Hruby, Victor J

    2009-12-18

    From a scientific perspective, efforts to understand biology including what constitutes health and disease has become a chemical problem. However, chemists and biologists "see" the problems of understanding biology from different perspectives, and this has retarded progress in solving the problems especially as they relate to health and disease. This suggests that close collaboration between chemists and biologists is not only necessary but essential for progress in both the biology and chemistry that will provide solutions to the global questions of biology. This perspective has directed my scientific efforts for the past 45 years, and in this overview I provide my perspective of how the applications of synthetic chemistry, structural design, and numerous other chemical principles have intersected in my collaborations with biologists to provide new tools, new science, and new insights that were only made possible and fruitful by these collaborations.

  18. ICTR-PHE: scientists engage with multidisciplinary research

    CERN Multimedia

    Antonella Del Rosso

    2015-01-01

    In 2016, the next edition of the unique conference that gathers scientists from a variety of fields will focus on many topics particularly dear to the heart of physicists, clinicians, biologists, and computer specialists. The call for abstracts is open until 16 October.   When detector physicists, radiochemists, nuclear-medicine physicians and other physicists, biologists, software developers, accelerator experts and oncologists think outside the box and get involved in multidisciplinary research, they create innovative healthcare. ICTR-PHE is a biennial event, co-organised by CERN, whose main aim is to foster multidisciplinary research by positioning itself at the crossing of physics, medicine and biology. At the ICTR-PHE conference, physicists, engineers, and computer scientists share their knowledge and technologies while doctors and biologists present their needs and vision for the medical tools of the future, thus triggering breakthrough ideas and technological developments in speci...

  19. Think Outside the Bio-Box

    Energy Technology Data Exchange (ETDEWEB)

    Wiley, H. S.

    2010-06-01

    After listening to my friends for many years (and reading numerous online comments in The Scientist), I was surprised that being a biologist was considered a low stress job with a bright future. Grousing about our jobs has always been a favorite pastime for biologists, but I suspect that in our hearts, we know how good we really have it. Even though research funding is tight and faculty positions are scarce, biologists still have one of the most interesting and exciting jobs around. I certainly don’t think that our current situation is worse than in the past. The real reason why the job outlook in biology seems dim is that research professors are training students to be university research scientists instead of preparing them for the broader job market. The result is that many new PhDs are frustrated to find that the specific positions they are trained for either don’t exist or have 300 applicants.

  20. Organic Chemistry and Biology: Chemical Biology Through the Eyes of Collaboration

    Science.gov (United States)

    Hruby, Victor J.

    2011-01-01

    From a scientific perspective, efforts to understand biology including what constitutes health and disease has become a chemical problem. However, chemists and biologists “see” the problems of understanding biology from different perspectives, and this has retarded progress in solving the problems especially as they relate to health and disease. This suggests that close collaboration between chemists and biologists is not only necessary but essential for progress in both the biology and chemistry that will provide solutions to the global questions of biology. This perspective has directed my scientific efforts for the past 45 years, and in this overview I provide my perspective of how the applications of synthetic chemistry, structural design, and numerous other chemical principles have intersected in my collaborations with biologists to provide new tools, new science, and new insights that were only made possible and fruitful by these collaborations. PMID:20000552

  1. Bioinspiration: applying mechanical design to experimental biology.

    Science.gov (United States)

    Flammang, Brooke E; Porter, Marianne E

    2011-07-01

    The production of bioinspired and biomimetic constructs has fostered much collaboration between biologists and engineers, although the extent of biological accuracy employed in the designs produced has not always been a priority. Even the exact definitions of "bioinspired" and "biomimetic" differ among biologists, engineers, and industrial designers, leading to confusion regarding the level of integration and replication of biological principles and physiology. By any name, biologically-inspired mechanical constructs have become an increasingly important research tool in experimental biology, offering the opportunity to focus research by creating model organisms that can be easily manipulated to fill a desired parameter space of structural and functional repertoires. Innovative researchers with both biological and engineering backgrounds have found ways to use bioinspired models to explore the biomechanics of organisms from all kingdoms to answer a variety of different questions. Bringing together these biologists and engineers will hopefully result in an open discourse of techniques and fruitful collaborations for experimental and industrial endeavors.

  2. Visualizing conserved gene location across microbe genomes

    Science.gov (United States)

    Shaw, Chris D.

    2009-01-01

    This paper introduces an analysis-based zoomable visualization technique for displaying the location of genes across many related species of microbes. The purpose of this visualizatiuon is to enable a biologist to examine the layout of genes in the organism of interest with respect to the gene organization of related organisms. During the genomic annotation process, the ability to observe gene organization in common with previously annotated genomes can help a biologist better confirm the structure and function of newly analyzed microbe DNA sequences. We have developed a visualization and analysis tool that enables the biologist to observe and examine gene organization among genomes, in the context of the primary sequence of interest. This paper describes the visualization and analysis steps, and presents a case study using a number of Rickettsia genomes.

  3. Learning in Plants: Lessons from Mimosa pudica

    Directory of Open Access Journals (Sweden)

    Charles Ira Abramson

    2016-03-01

    Full Text Available This article provides an overview of the early Mimosa pudica literature; much of which is in journals not easily accessible to the reader. In contrast to the contemporary plant learning literature which is conducted primarily by plant biologists, this early literature was conducted by comparative psychologists whose goal was to search for the generality of learning phenomena such as habituation, and classical conditioning using experimental designs based on animal conditioning studies. In addition to reviewing the early literature, we hope to encourage collaborations between plant biologists and comparative psychologists by familiarizing the reader with issues in the study of learning faced by those working with animals. These issues include no consistent definition of learning phenomena and an overreliance on the use of cognition. We suggested that greater collaborative efforts be made between plant biologists and comparative psychologists if the study of plant learning is to be fully intergraded into the mainstream behavior theory.

  4. Mathematics and biology

    International Nuclear Information System (INIS)

    Khan, I.A.

    1991-06-01

    In India and in so many other countries, the science students are generally separated into two main streams: one opting mathematical sciences, the other studying biological sciences. As a result, medicos and biologists have no adequate knowledge of mathematical sciences. It causes a great drawback to them in order to be perfect and updated in their profession, due to the tremendous application of mathematics in bio-sciences, now-a-days. The main aim of this article is to emphasize on the need of the time to produce the mathematico-biologists in abundance for the better service of mankind. (author)

  5. Meeting report--Getting Into and Out of Mitosis.

    Science.gov (United States)

    Mchedlishvili, Nunu; Jonak, Katarzyna; Saurin, Adrian T

    2015-11-15

    The Company of Biologists Workshop 'Getting Into and Out of Mitosis' was held 10-13 May 2015 at Wiston House in West Sussex, UK. The workshop brought together researchers from wide-ranging disciplines and provided a forum to discuss their latest work on the control of cell division from mitotic entry to exit. This report highlights the main topics and summarises the discussion around the key themes and questions that emerged from the meeting. © 2015. Published by The Company of Biologists Ltd.

  6. Stem cell migration - Methods and protocols

    Directory of Open Access Journals (Sweden)

    Carlo Alberto Redi

    2012-03-01

    Full Text Available The trafficking of stem cells is something unconsciously clear to any biologists (e.g., developmental biologists and physicians (e.g., all those taking care of hematopoietic and bone diseases and traumas; neverthless it is a phenomenon coming out as a hot topic just in these last years. Likely, the difficulties to track stem cells migration in vivo and the understanding of the elusive homing signals matching the circulating stem cells properties that makes these cells to stop and to start multiplication and differentiation....

  7. CURE Scholar Spotlight - Dr. Brady

    Science.gov (United States)

    Donita C. Brady, a Research Associate Senior at the Department of Pharmacology and Cancer Biology at Duke University, is investigating the role that copper plays in cell growth and tumor biology. Inspired by her mentor Christopher Counter, a cancer biologist, and Dennis Thiele, a copper biologist, at Duke University, Brady has a unique interest in the way copper interacts with protein pathways, such as the BRAF (a human gene that directs cell growth)-MEK-ERK pathway, which is a major target for targeted cancer therapies because the BRAF gene is mutated 60% of the time in melanoma.

  8. Can Cybersemiotics Solve the Paradox of Transdisciplinary Knowing?

    DEFF Research Database (Denmark)

    Brier, Søren

    2014-01-01

    conceived, connects our perception with our thinking, communication, and acting in the social world. Unfortunately,each of the four worlds has historically developed its own type of narrative, with its own fundamentalist and reductionist verions vitiating the project of transdisciplinarity. Physicists...... and chemists tend to view the universe as consisting of matter, forces, and energy. Mechanistically oriented biologists extend this view into their subject area. But cybernetic- and semiotic-oriented biologists perceive living systems as the basic organizers of reality, possessing self-protecting, and self...

  9. Biology, politics, and the emerging science of human nature.

    Science.gov (United States)

    Fowler, James H; Schreiber, Darren

    2008-11-07

    In the past 50 years, biologists have learned a tremendous amount about human brain function and its genetic basis. At the same time, political scientists have been intensively studying the effect of the social and institutional environment on mass political attitudes and behaviors. However, these separate fields of inquiry are subject to inherent limitations that may only be resolved through collaboration across disciplines. We describe recent advances and argue that biologists and political scientists must work together to advance a new science of human nature.

  10. Zebrafish: swimming towards a role for fanconi genes in DNA repair.

    Science.gov (United States)

    Scata, Kimberly A; El-Deiry, Wafik S

    2004-06-01

    The zebrafish, Danio rerio, has become a favorite model organism for geneticists and developmental biologists. Recently cancer biologists have turned to this tiny fish to help them unravel the mysteries of conserved pathways such as the Fanconi Anemia (FA) pathway. Although a relatively rare disease, the genes involved in FA are part of a large network of DNA damage response/repair genes. Liu and colleagues have recapitulated some of the clinical manifestations of human FA by knocking down the zebrafish FANC-D2 gene thereby providing a new model for probing the underlying causes of these phenotypes.

  11. The art of editing RNA structural alignments

    DEFF Research Database (Denmark)

    Andersen, Ebbe Sloth

    2014-01-01

    Manual editing of RNA structural alignments may be considered more art than science, since it still requires an expert biologist to take multiple levels of information into account and be slightly creative when constructing high-quality alignments. Even though the task is rather tedious, it is re......Manual editing of RNA structural alignments may be considered more art than science, since it still requires an expert biologist to take multiple levels of information into account and be slightly creative when constructing high-quality alignments. Even though the task is rather tedious...

  12. Improving our chemistry: challenges and opportunities in the interdisciplinary study of floral volatiles.

    Science.gov (United States)

    Raguso, R A; Thompson, J N; Campbell, D R

    2015-07-01

    The field of chemical ecology was established, in large part, through collaborative studies between biologists and chemists with common interests in the mechanisms that mediate chemical communication in ecological and evolutionary contexts. Pollination is one highly diverse and important category of such interactions, and there is growing evidence that floral volatiles play important roles in mediating pollinator behaviour and its consequences for plant reproductive ecology and evolution. Here we outline next-generation questions emerging in the study of plants and pollinators, and discuss the potential for strengthening collaboration between biologists and chemists in answering such questions.

  13. The Next Nuclear Gamble. Transportation and storage of nuclear waste

    International Nuclear Information System (INIS)

    Resnikoff, M.

    1985-01-01

    The Next Nuclear Gamble examines risks, costs, and alternatives in handling irradiated nuclear fuel. The debate over nuclear power and the disposal of its high-level radioactive waste is now nearly four decades old. Ever larger quantities of commercial radioactive fuel continue to accumulate in reactor storage pools throughout the country and no permanent storage solution has yet been designated. As an interim solution, the government and utilities prefer that radioactive wastes be transported to temporary storage facilities and subsequently to a permanent depository. If this temporary and centralized storage system is implemented, however, the number of nuclear waste shipments on the highway will increase one hundredfold over the next fifteen years. The question directly addressed is whether nuclear transport is safe or represents the American public's domestic nuclear gamble. This Council on Economic Priorities study, directed by Marvin Resnikoff, shows on the basis of hundreds of government and industry reports, interviews and surveys, and original research, that transportation of nuclear materials as currently practiced is unsafe

  14. Paternal versus maternal coping styles with child diagnosis of developmental delay.

    Science.gov (United States)

    Barak-Levy, Yael; Atzaba-Poria, Na'ama

    2013-06-01

    Parents of children with disabilities vary in their reaction to their children's diagnosis. The current study focused on fathers in addition to mothers and examined their resolution and coping styles when having children diagnosed with developmental delay (DD). Sixty-five fathers and 71 mothers were interviewed using the reaction to the diagnosis interview (RDI; Pianta & Marvin, 1992a). Results indicated that the majority of parents were unresolved with their child's diagnosis, with no differences found between fathers' and mothers' rates of resolution. Furthermore, both parents of children that were diagnosed at a later age and parents that were less educated tended to be unresolved, as did fathers of a lower socioeconomic status. Older age of both children and mothers was related to maternal lack of resolution. Finally, an in-depth examination revealed significant differences in the manner in which fathers and mothers cope with their children's diagnosis: whereas mothers were more prone to using an emotional coping style, fathers tended to use a cognitive coping style. The clinical implications of paternal versus maternal coping styles are discussed. Copyright © 2013 Elsevier Ltd. All rights reserved.

  15. Closeout for U.S. Department of Energy Final Technical Report for University of Arizona grant DOE Award Number DE-FG03-95ER40906 From 1 February 1995 to 31 January 2004 Grant title: Theory and Phenomenology of Strong and Weak High Energy Physics (Task A) and Experimental Elementary Particle Physics (Task B)

    Energy Technology Data Exchange (ETDEWEB)

    Rutherfoord, John; Toussaint, Doug; Sarcevic, Ina

    2005-03-03

    The following pages describe the high energy physics program at the University of Arizona which was funded by DOE grant DE-FG03-95ER40906, for the period 1 February 1995 to 31 January 2004. In this report, emphasis was placed on more recent accomplishments. This grant was divided into two tasks, a theory task (Task A) and an experimental task (Task B but called Task C early in the grant period) with separate budgets. Faculty supported by this grant, for at least part of this period, include, for the theory task, Adrian Patrascioiu (now deceased), Ina Sarcevic, and Douglas Toussaint., and, for the experimental task, Elliott Cheu, Geoffrey Forden, Kenneth Johns, John Rutherfoord, Michael Shupe, and Erich Varnes. Grant monitors from the Germantown DOE office, overseeing our grant, changed over the years. Dr. Marvin Gettner covered the first years and then he retired from the DOE. Dr. Patrick Rapp worked with us for just a few years and then left for a position at the University of Puerto Rico. Dr. Kathleen Turner took his place and continues as our grant monitor. The next section of this report covers the activities of the theory task (Task A) and the last section the activities of the experimental task (Task B).

  16. Compilation of radiometric age and trace-element geochemical data, Yucca Mountain and surrounding areas of southwestern Nevada

    International Nuclear Information System (INIS)

    Weiss, S.I.; Noble, D.C.; Larson, L.T.

    1994-01-01

    This document is a compilation of available radiometric age and trace-element geochemical data for volcanic rocks and episodes of hydrothermal activity in Yucca Mountain and the surrounding region of southwestern Nevada. Only the age determinations considered to be geologically reasonable (consistent with stratigraphic relations) are listed below. A number of the potassium-argon (K-Ar) ages of volcanic rocks given by Kistler, Marvin et al., Noble et al., Weiss et al., and Noble et al. are not included as these ages have been shown to be incorrect or disturbed by hydrothermal alteration based on subsequent stratigraphic and/or petrographic data and the recognition of errors in K-Ar age determinations related to incomplete extraction of argon. In cases where absolute ages are tightly constrained by high precision 40 Ar/ 39 Ar ages and unequivocal stratigraphic relations, we have omitted the less precise K-Ar age data. Similarly, the more precise single-crystal laser-fusion 40 Ar/ 39 Ar age determinations of certain units are reported and less precise ages by multi-grain bulk-fusion 40 Ar/ 39 Ar methods are not included. This compilation does not include age data for basaltic rocks of Pliocene and Quaternary age in the Yucca Mountain region

  17. pKa-critical Interpretations of Solubility–pH Profiles: PG 300995 and NSC-639829 Case Studies

    Directory of Open Access Journals (Sweden)

    George Butcher

    2015-07-01

    Full Text Available Two weak bases, PG-300995 (anti-HIV agent and NSC-639829 (anti-tumor agent, whose log S – pH profiles had been previously published, but whose pKa values had not been reported, were analyzed using a method which can determine pKa values from log S – pH data. This “SpH-pKa” technique, although often practiced, can result in inaccurate pKa values, for a variety of reasons. The operational SpH-pKa values were compared to those predicted by MarvinSketch (ChemAxon, ADMET Predictor (Simulation Plus, and ACD/Percepta (ACD/Labs. The agreement for the sparingly-soluble PG-300995 was reasonably good. However, a substantial difference was found for the practically-insoluble NSC-639829. To probe this further, the pKa of NSC‑639829 was measured by an independent spectrophotometric cosolvent technique. The log S - pH profile of NSC-639829 was then re‑analyzed with the independently-measured pKa. It was found that the equilibrium model which best fit the solubility data is consistent with the presence of a monocationic NSC-639829 dimeric species below pH 4. This illustrates that an independently-determined accurate pKa is critical to mechanistic interpretations of solubility-pH data. Apparently, the Henderson-Hasselbalch equation holds for PG-300995, but not NSC-639829.

  18. Cruzando el Rubicón: del psicoanálisis a la terapia cognitiva

    Directory of Open Access Journals (Sweden)

    Guido Pablo Korman

    Full Text Available Resumen En este trabajo nos proponemos describir algunas de las causas que llevan a Aaron T. Beck a abandonar el psicoanálisis y a participar de la creación de la terapia cognitiva. Para ello, describiremos los trabajos de investigación desarrollados por Beck entre los años 1959 y 1962. En ellos se empiezan a procesar los datos que darán lugar a la caída de la hipótesis explicativa psicoanalítica de la depresión. Dentro de este análisis incluiremos algunos elementos que consideramos esenciales para entender este proceso de cambio: la obtención de un subsidio para investigar la depresión y la aparición de colaboradores como Marvin Hurvich y Seygmour Feshbach, cuyas nuevas herramientas y metodologías ayudaron a Beck a poner a prueba la hipótesis psicoanalítica de la depresión. Por último, incluiremos cuestiones referidas a las políticas de investigación del Instituto Nacional de Salud Mental, así como motivos personales y de la política institucional.

  19. SuperNatural: a searchable database of available natural compounds.

    Science.gov (United States)

    Dunkel, Mathias; Fullbeck, Melanie; Neumann, Stefanie; Preissner, Robert

    2006-01-01

    Although tremendous effort has been put into synthetic libraries, most drugs on the market are still natural compounds or derivatives thereof. There are encyclopaedias of natural compounds, but the availability of these compounds is often unclear and catalogues from numerous suppliers have to be checked. To overcome these problems we have compiled a database of approximately 50,000 natural compounds from different suppliers. To enable efficient identification of the desired compounds, we have implemented substructure searches with typical templates. Starting points for in silico screenings are about 2500 well-known and classified natural compounds from a compendium that we have added. Possible medical applications can be ascertained via automatic searches for similar drugs in a free conformational drug database containing WHO indications. Furthermore, we have computed about three million conformers, which are deployed to account for the flexibilities of the compounds when the 3D superposition algorithm that we have developed is used. The SuperNatural Database is publicly available at http://bioinformatics.charite.de/supernatural. Viewing requires the free Chime-plugin from MDL (Chime) or Java2 Runtime Environment (MView), which is also necessary for using Marvin application for chemical drawing.

  20. Transporting spent reactor fuel: allegations and responses

    International Nuclear Information System (INIS)

    Jefferson, R.M.

    1983-03-01

    A January 1982 monthly newsletter from the Council on Economic Priorities (CEP) was entirely devoted to the presentation of a broad-ranging series of allegations that the transportation of spent fuel in particular, and other high-level radioactive materials by inference is currently being conducted in this country in an unsafe manner. This newsletter preceded the release of a book authored by Marvin Resnikoff on the same subject by over a year. This book titled The Next Nuclear Gamble contained substantially the same allegations as the newsletter, although the book devoted space to a greatly increased number of specific examples. This paper reduces those allegations contained in the executive summary and the recommendations contained in the last chapter of the book to a manageable number by combining the many specific issues into a few topics. Each of these topics is then addressed. As such, this is an abbreviated analysis of The Next Nuclear Gamble and does not address much of the fine detail. In spite of that, it would be possible to address each of the details within the book on a similar basis. The intent of this document is to provide background information for those who are questioned on the validity of the allegations made by the CEp

  1. Distributed chemical computing using ChemStar: an open source java remote method invocation architecture applied to large scale molecular data from PubChem.

    Science.gov (United States)

    Karthikeyan, M; Krishnan, S; Pandey, Anil Kumar; Bender, Andreas; Tropsha, Alexander

    2008-04-01

    We present the application of a Java remote method invocation (RMI) based open source architecture to distributed chemical computing. This architecture was previously employed for distributed data harvesting of chemical information from the Internet via the Google application programming interface (API; ChemXtreme). Due to its open source character and its flexibility, the underlying server/client framework can be quickly adopted to virtually every computational task that can be parallelized. Here, we present the server/client communication framework as well as an application to distributed computing of chemical properties on a large scale (currently the size of PubChem; about 18 million compounds), using both the Marvin toolkit as well as the open source JOELib package. As an application, for this set of compounds, the agreement of log P and TPSA between the packages was compared. Outliers were found to be mostly non-druglike compounds and differences could usually be explained by differences in the underlying algorithms. ChemStar is the first open source distributed chemical computing environment built on Java RMI, which is also easily adaptable to user demands due to its "plug-in architecture". The complete source codes as well as calculated properties along with links to PubChem resources are available on the Internet via a graphical user interface at http://moltable.ncl.res.in/chemstar/.

  2. Fragment-based approach to calculate hydrophobicity of anionic and nonionic surfactants derived from chromatographic retention on a C18 stationary phase.

    Science.gov (United States)

    Hammer, Jort; Haftka, Joris J-H; Scherpenisse, Peter; Hermens, Joop L M; de Voogt, Pim W P

    2017-02-01

    To predict the fate and potential effects of organic contaminants, information about their hydrophobicity is required. However, common parameters to describe the hydrophobicity of organic compounds (e.g., octanol-water partition constant [K OW ]) proved to be inadequate for ionic and nonionic surfactants because of their surface-active properties. As an alternative approach to determine their hydrophobicity, the aim of the present study was therefore to measure the retention of a wide range of surfactants on a C 18 stationary phase. Capacity factors in pure water (k' 0 ) increased linearly with increasing number of carbon atoms in the surfactant structure. Fragment contribution values were determined for each structural unit with multilinear regression, and the results were consistent with the expected influence of these fragments on the hydrophobicity of surfactants. Capacity factors of reference compounds and log K OW values from the literature were used to estimate log K OW values for surfactants (log KOWHPLC). These log KOWHPLC values were also compared to log K OW values calculated with 4 computational programs: KOWWIN, Marvin calculator, SPARC, and COSMOThermX. In conclusion, capacity factors from a C 18 stationary phase are found to better reflect hydrophobicity of surfactants than their K OW values. Environ Toxicol Chem 2017;36:329-336. © 2016 The Authors. Environmental Toxicology and Chemistry Published by Wiley Periodicals, Inc. on behalf of SETAC. © 2016 The Authors. Environmental Toxicology and Chemistry Published by Wiley Periodicals, Inc. on behalf of SETAC.

  3. Efficacy and safety of fentanyl buccal for cancer pain management by administration through a soluble film: an update

    Directory of Open Access Journals (Sweden)

    Marvin Omar Delgado-Guay

    2010-11-01

    Full Text Available Marvin Omar Delgado-GuayDivision of Geriatrics and Palliative Medicine, The University of Texas, Medical School at Houston, Houston, TX, USAAbstract: More than half of patients receiving prescription medicine for cancer pain have been reported to experience inadequate pain relief or breakthrough pain. Buccal administration can deliver lipophilic opioids rapidly to the systemic circulation through the buccal mucosa, limiting gastrointestinal motility and first-pass metabolism. This review updates the safety and efficacy of fentanyl buccal soluble film (FBSF in patients with cancer pain. Literature was identified through searches of Medline (PubMed. Search terms included combinations of the following: cancer pain, fentanyl, fentanyl buccal soluble film, pharmacology, kinetics, safety, efficacy and toxicity. FBSF is an oral transmucosal form of fentanyl citrate developed as a treatment of breakthrough pain in opioid-tolerant patients with cancer. Studies have shown that it is well tolerated in the oral cavity, with adequate bioavailability and safety in cancer patients. Further studies are warranted to evaluate, in comparison with other short-acting opioids, its efficacy in the management of breakthrough cancer pain, its addictive potential and its economic impact in cancer patients.Keywords: fentanyl buccal soluble film, cancer pain

  4. Characterizing Milky Way Tidal Streams and Dark Matter with MilkyWay@home

    Science.gov (United States)

    Newberg, Heidi Jo; Shelton, Siddhartha; Weiss, Jake

    2018-01-01

    MilkyWay@home is a 0.5 PetaFLOPS volunteer computing platform that is mapping out the density substructure of the Sagittarius Dwarf Tidal Stream, the so-called bifurcated portion of the Sagittarius Stream, and the Virgo Overdensity, using turnoff stars from the Sloan Digital Sky Survey. It is also using the density of stars along tidal streams such as the Orphan Stream to constrain properties of the dwarf galaxy progenitor of this stream, including the dark matter portion. Both of these programs are enabled by a specially-built optimization package that uses differential evolution or particle swarm methods to find the optimal model parameters to fit a set of data. To fit the density of tidal streams, 20 parameters are simultaneously fit to each 2.5-degree-wide stripe of SDSS data. Five parameters describing the stellar and dark matter profile of the Orphan Stream progenitor and the time that the dwarf galaxy has been evolved through the Galactic potential are used in an n-body simulation that is then fit to observations of the Orphan Stream. New results from MilkyWay@home will be presented. This project was supported by NSF grant AST 16-15688, the NASA/NY Space Grant fellowship, and contributions made by The Marvin Clan, Babette Josephs, Manit Limlamai, and the 2015 Crowd Funding Campaign to Support Milky Way Research.

  5. Closeout for U.S. Department of Energy Final Technical Report for University of Arizona grant DOE Award Number DE-FG03-95ER40906 From 1 February 1995 to 31 January 2004 Grant title: Theory and Phenomenology of Strong and Weak High Energy Physics (Task A) and Experimental Elementary Particle Physics (Task B)

    International Nuclear Information System (INIS)

    Rutherfoord, John; Toussaint, Doug; Sarcevic, Ina

    2005-01-01

    The following pages describe the high energy physics program at the University of Arizona which was funded by DOE grant DE-FG03-95ER40906, for the period 1 February 1995 to 31 January 2004. In this report, emphasis was placed on more recent accomplishments. This grant was divided into two tasks, a theory task (Task A) and an experimental task (Task B but called Task C early in the grant period) with separate budgets. Faculty supported by this grant, for at least part of this period, include, for the theory task, Adrian Patrascioiu (now deceased), Ina Sarcevic, and Douglas Toussaint., and, for the experimental task, Elliott Cheu, Geoffrey Forden, Kenneth Johns, John Rutherfoord, Michael Shupe, and Erich Varnes. Grant monitors from the Germantown DOE office, overseeing our grant, changed over the years. Dr. Marvin Gettner covered the first years and then he retired from the DOE. Dr. Patrick Rapp worked with us for just a few years and then left for a position at the University of Puerto Rico. Dr. Kathleen Turner took his place and continues as our grant monitor. The next section of this report covers the activities of the theory task (Task A) and the last section the activities of the experimental task (Task B)

  6. The structure of the lexical personality descriptors in Serbian language

    Directory of Open Access Journals (Sweden)

    Smederevac Snežana

    2007-01-01

    Full Text Available Two studies, both originating from a larger psycholexical study in Serbian language, are presented here. Two questionnaires, Lexi and PL have been constructed in the psycholexical study. The questionnaires differ by the formulation of their respective items: while the items of the Lexi contain adjectives, the items of the PL are in the form of statements. The first study presented in this paper examines the latent structure of the Lexi questionnaire, while the second one deals with the latent structure of the PL. In both studies, principal component analysis was applied, and the number of components to be retained in the analysis was determined according to the Scree criterion. Also, Promax rotation was applied in both studies. Seven components which were extracted in the first study have been interpreted as Negative Valence, Negative Emotionality, Aggressiveness, Conscientiousness, Positive Emotionality, Positive Valence and Openness to Experience. The content of these dimensions is obviously similar to the dimensions of Tellegen and Waller’s Big Seven model. In the second study, five components were extracted, and interpreted as Sociability, Anxiety, Aggressiveness, Activity and Impulsivity. The content of the dimensions extracted in the second study corresponds with the dimensions of Marvin Zuckerman’s Alternative Five - Factor Model.

  7. How to dispose of the other radwaste

    International Nuclear Information System (INIS)

    Anon.

    1987-01-01

    While the US Department of Energy searches for a repository for the highly radioactive spent fuel from nuclear power plants, federal law requires the states by January to have plans for establishing regional landfill sites for the disposal of so-called low-level radioactive waste. But a recent report from the Radioactive Waste Campaign in New York calls for ending the landfill approach to disposal of low-level waste in order to avoid the leakage and contamination of water supplies that have wracked existing landfills. According to physicist Marvin Resnikoff, author of the report, low-level waste is a misnomer for what often includes extremely long-lived radioactive waste requiring more careful disposal. Because 99% of the radioactivity and 70% of the volume of low-level waste comes from power reactors, Resnikoff advocates disposal on the plant site. He also advocates separation of wastes by their half-life and reclassification as high level of the long-lived radioactive waste from decommissioned plants. The much smaller volume of industrial and institutional waste should be supercompacted and also transferred to the plants for storage. The report further recommends a Manhattan Project-style effort to deal with the problem of radioactive waste as a whole

  8. Shmuel Malkin (1934-2017) : Listening to photosynthesis and making music.

    Science.gov (United States)

    Herbert, Stephen K; Siderer, Yona; Govindjee

    2018-07-01

    We present here the life and work of Shmuel Malkin (1934-2017), an accomplished scientist and a gifted musician who touched the lives of many around the world. His early scientific work addressed the dynamics of light harvesting and electron transport in photosynthesis. Later, he used photoacoustic and photothermal methodologies to explore all aspects of photosynthesis. As a musician, Shmuel played the piano often for family and friends but after his formal retirement, he produced a body of original musical compositions, many of which were performed publicly. Throughout his life, Shmuel was a caring and deeply thoughtful man, respected and loved by colleagues, family, and friends. This tribute presents a summary of Shmuel's work as well as remembrances written by his wife, Nava Malkin, their son, Eyal Malkinson, and many of his colleagues: Michael Havaux from France; Sandra and Marcel Jansen from Ireland; David Cahen, Marvin Edelmann, Joop and Onnie de Graaf, Jonathan Gressel, Uri Pick, Yona Siderer, and Elisha Tel-Or from Israel; Ulrich Schreiber from Germany; James Barber and Alison Telfer from the UK; Govindjee, Stephen Herbert and Thomas Sharkey from the USA. Minnie Ho and Iris Malkin of the USA wrote contributions about Shmuel's music.

  9. Nature as Measure

    DEFF Research Database (Denmark)

    Peters, Terri

    2011-01-01

    The potential for biomimicry lies far beyond the direct imitation of natural forms. Guest-editor Terri Peters describes how Janine Benyus, the biologist and innovation consultant, is using biomimicry to create performance metrics from natural technologies and processes for assessing aspects...

  10. Update on protein structure prediction: results of the 1995 IRBM workshop

    DEFF Research Database (Denmark)

    Hubbard, Tim; Tramontano, Anna; Hansen, Jan

    1996-01-01

    Computational tools for protein structure prediction are of great interest to molecular, structural and theoretical biologists due to a rapidly increasing number of protein sequences with no known structure. In October 1995, a workshop was held at IRBM to predict as much as possible about a numbe...

  11. Metrological data and risk assessment in France during the Chernobyl accident (26 april 1986)

    International Nuclear Information System (INIS)

    Galle, P.; Paulin, R.; Coursaget, J.

    2005-01-01

    Three world famous radio biologists have presented in june 2003 a communication entitled ' metrological data and risk assessment in France during the Chernobyl accident. Historical statement'. This text is published at the tome 326, fsc. 8, page 699-715 at the 'Comptes Rendus de Biologie de l'Academie'. The digest is presented here. (N.C.)

  12. Emergentism as a default: Cancer as a problem of tissue organization

    Indian Academy of Sciences (India)

    2004-09-27

    Sep 27, 2004 ... The optimism of molecular biologists, fueled by early success in tackling relatively simple problems, has now been tempered by the difficulties found when attempting to understand complex biological problems. Here, we analyse experimental data that illustrate the shortcomings of this sort of reductionism.

  13. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2009-08-19

    Aug 19, 2009 ... Home; Journals; Journal of Biosciences; Volume 34; Issue 3. What history tells us XVIII. When functional biologists propose mechanisms of evolution. Michel Morange. Series Volume 34 Issue 3 September 2009 pp 373-376. Fulltext. Click here to view fulltext PDF. Permanent link:

  14. The Practice of Water Pollution Biology.

    Science.gov (United States)

    Mackenthun, Kenneth M.

    Water pollution techniques and practices, including data analysis, interpretation and display are described in this book intended primarily for the biologist inexperienced in this work, and for sanitary engineers, chemists, and water pollution control administrators. The characteristics of aquatic environments, their biota, and the effects of…

  15. Testing gradual and speciational models of evolution in extant taxa: the example of ratites

    NARCIS (Netherlands)

    Laurin, M.; Gussekloo, S.W.S.; Marjanovic, D.; Legendre, L.; Cubo, J.

    2012-01-01

    Ever since Eldredge and Gould proposed their model of punctuated equilibria, evolutionary biologists have debated how often this model is the best description of nature and how important it is compared to the more gradual models of evolution expected from natural selection and the neo-Darwinian

  16. Taming Living Logic using Formal Methods

    DEFF Research Database (Denmark)

    Baig, Hasan; Madsen, Jan

    2017-01-01

    One of the goals of synthetic biology is to build genetic circuits to control the behavior of a cell for different application domains, such as medical, environmental, and biotech. During the design process of genetic circuits, biologists are often interested in the probability of a system to work...

  17. Photography of Coral Reefs from ISS

    Science.gov (United States)

    Robinson, Julie A.

    2009-01-01

    This viewgraph presentation reviews the uses of photography from the International Space Station (ISS) in studying Earth's coral reefs. The photographs include reefs in various oceans . The photographs have uses for science in assisting NASA mapping initiatives, distribution worldwide through ReefBase, and by biologist in the field.

  18. Emerging Scholars: The Class of 2008

    Science.gov (United States)

    Forde, Dana; Lum, Lydia; Nealy, Michelle J.; Pluviose, David; Roach, Ronald; Rogers, Ibram; Rolo, Mark Anthony; Seymour, Add, Jr., Valdata, Patricia; Watson, Jamal

    2008-01-01

    This year's crop of "Emerging Scholars"--The Class of 2008--includes a math biologist who was only the second woman to receive the Alfred P. Sloan Fellowship in math; a geneticist who recently became one of 20 winners of the National Science Foundation's Presidential Early Career Awards for Scientists and Engineers; and an extensively published…

  19. How to Identify and Interpret Evolutionary Tree Diagrams

    Science.gov (United States)

    Kong, Yi; Anderson, Trevor; Pelaez, Nancy

    2016-01-01

    Evolutionary trees are key tools for modern biology and are commonly portrayed in textbooks to promote learning about biological evolution. However, many people have difficulty in understanding what evolutionary trees are meant to portray. In fact, some ideas that current professional biologists depict with evolutionary trees are neither clearly…

  20. Exploring the MACH Model's Potential as a Metacognitive Tool to Help Undergraduate Students Monitor Their Explanations of Biological Mechanisms

    Science.gov (United States)

    Trujillo, Caleb M.; Anderson, Trevor R.; Pelaez, Nancy J.

    2016-01-01

    When undergraduate biology students learn to explain biological mechanisms, they face many challenges and may overestimate their understanding of living systems. Previously, we developed the MACH model of four components used by expert biologists to explain mechanisms: Methods, Analogies, Context, and How. This study explores the implementation of…

  1. How to Build a Course in Mathematical-Biological Modeling: Content and Processes for Knowledge and Skill

    Science.gov (United States)

    Hoskinson, Anne-Marie

    2010-01-01

    Biological problems in the twenty-first century are complex and require mathematical insight, often resulting in mathematical models of biological systems. Building mathematical-biological models requires cooperation among biologists and mathematicians, and mastery of building models. A new course in mathematical modeling presented the opportunity…

  2. The Strategies of Modeling in Biology Education

    Science.gov (United States)

    Svoboda, Julia; Passmore, Cynthia

    2013-01-01

    Modeling, like inquiry more generally, is not a single method, but rather a complex suite of strategies. Philosophers of biology, citing the diverse aims, interests, and disciplinary cultures of biologists, argue that modeling is best understood in the context of its epistemic aims and cognitive payoffs. In the science education literature,…

  3. A lock-and-key model for protein–protein interactions

    NARCIS (Netherlands)

    Morrison, Julie L.; Breitling, Rainer; Higham, Desmond J.; Gilbert, David R.

    2006-01-01

    Motivation: Protein–protein interaction networks are one of the major post-genomic data sources available to molecular biologists. They provide a comprehensive view of the global interaction structure of an organism’s proteome, as well as detailed information on specific interactions. Here we

  4. 75 FR 61904 - Endangered and Threatened Wildlife and Plants; Proposed Listings for Two Distinct Population...

    Science.gov (United States)

    2010-10-06

    ... distributed along the eastern coast of North America. Historically, sightings have been reported from Hamilton..., thus limiting the amount of freshwater spawning and developmental habitat for fish below the dams. In... (SRT) consisting of Federal biologists from NMFS, U.S. Geological Survey (USGS), and U.S. Fish and...

  5. Human cultural diversity in prehistoric Fiji

    Directory of Open Access Journals (Sweden)

    Ethan E. Cochrane

    2005-08-01

    Full Text Available Remote islands and their human, animal and plant populations have long fascinated archaeologists, biologists and geographers. In this article, the chronology, diversity and interactions of human cultures in some small islands of the Fiji archipelago are explored, particularly through the application of sophisticated chemical analyses of the composition of prehistoric pottery.

  6. Nomenclature of the finer branches of the biliary tree : Canals, ductules, and ductular reactions in human livers

    NARCIS (Netherlands)

    Roskams, TA; Theise, ND; Balabaud, C; Bhagat, G; Bhathal, PS; Bioulac-Sage, P; Brunt, EM; Crawford, JM; Crosby, HA; Desmet, [No Value; Finegold, MJ; Geller, SA; Gouw, ASH; Hytiroglou, P; Knisely, AS; Kojiro, M; Letkowitch, JH; Nakanuma, Y; Olynyk, JK; Park, YN; Portmann, B; Saxena, R; Scheuer, PJ; Strain, AJ; Thung, SN; Wanless, IR; West, AB

    The work of liver stem cell biologists, largely carried out in rodent models, has now started to manifest in human investigations and applications. We can now recognize complex regenerative processes in tissue specimens that had only been suspected for decades, but we also struggle to describe what

  7. Northwest range-plant symbols adapted to automatic data processing.

    Science.gov (United States)

    George A. Garrison; Jon M. Skovlin

    1960-01-01

    Many range technicians, agronomists, foresters, biologists, and botanists of various educational institutions and government agencies in the Northwest have been using a four-letter symbol list or code compiled 12 years ago from records of plants collected by the U.S. Forest Service in Oregon and Washington, This code has served well as a means of entering plant names...

  8. Invasion versus isolation: Trade-offs in managing native salmonids with barriers to upstream movement

    Science.gov (United States)

    Kurt D. Fausch; Bruce E. Rieman; Jason B. Dunham; Michael K. Young; Douglas P. Peterson

    2009-01-01

    Conservation biologists often face the trade-off that increasing connectivity in fragmented landscapes to reduce extinction risk of native species can foster invasion by non-native species that enter via the corridors created, which can then increase extinction risk. This dilemma is acute for stream fishes, especially native salmonids, because their populations are...

  9. Making Sense of Scientific Biographies: Scientific Achievement, Nature of Science, and Storylines in College Students' Essays

    Science.gov (United States)

    Hwang, Seyoung

    2015-01-01

    In this article, the educative value of scientific biographies will be explored, especially for non-science major college students. During the "Scientist's life and thought" course, 66 college students read nine scientific biographies including five biologists, covering the canonical scientific achievements in Western scientific history.…

  10. to view fulltext PDF

    Indian Academy of Sciences (India)

    While biologists are still required to validate the computer-generated models, by ..... language, and I started writing more complex programs – for example, fitting .... It is time to get going on constructing a model of the cell for real, and there are.

  11. 76 FR 66805 - Endangered and Threatened Wildlife and Plants: Final Rulemaking To Designate Critical Habitat for...

    Science.gov (United States)

    2011-10-27

    ... Raimondi, University of California Santa Cruz (UCSC), in 2005). Black abalone generally inhabit coastal and... final rules through press releases, the Federal Register, and posting of the rules and supporting... CHRT, comprised of seven Federal biologists from NMFS, the National Park Service (NPS), US Geological...

  12. Physics and Biology Collaborate to Color the World

    Science.gov (United States)

    Liu, Dennis W. C.

    2013-01-01

    To understand how life works, it is essential to understand physics and chemistry. Most biologists have a clear notion of where chemistry fits into their life sciences research and teaching. Although we are physical beings, physics does not always find a place in the biology curriculum. Physics informs and enlightens biology in myriad dimensions,…

  13. The Case for "Story-Driven" Biology Education

    Science.gov (United States)

    Schattner, Peter

    2015-01-01

    Can learning molecular biology and genetics be enjoyable? Of course it can. Biologists know their field is exciting and fascinating and that learning how cells and molecules shape the living world is extraordinarily interesting. But can students who are not already inclined towards science also be convinced that learning molecular biology is…

  14. Development of the Biology Card Sorting Task to Measure Conceptual Expertise in Biology

    Science.gov (United States)

    Smith, Julia I.; Combs, Elijah D.; Nagami, Paul H.; Alto, Valerie M.; Goh, Henry G.; Gourdet, Muryam A. A.; Hough, Christina M.; Nickell, Ashley E.; Peer, Adrian G.; Coley, John D.; Tanner, Kimberly D.

    2013-01-01

    There are widespread aspirations to focus undergraduate biology education on teaching students to think conceptually like biologists; however, there is a dearth of assessment tools designed to measure progress from novice to expert biological conceptual thinking. We present the development of a novel assessment tool, the Biology Card Sorting Task,…

  15. Using Mathematics and Engineering to Solve Problems in Secondary Level Biology

    Science.gov (United States)

    Cox, Charles; Reynolds, Birdy; Schunn, Christian; Schuchardt, Anita

    2016-01-01

    There are strong classroom ties between mathematics and the sciences of physics and chemistry, but those ties seem weaker between mathematics and biology. Practicing biologists realize both that there are interesting mathematics problems in biology, and that viewing classroom biology in the context of another discipline could support students'…

  16. Marine Flora and Fauna of the Northeastern United States. Echinodermata: Holothuroidea.

    Science.gov (United States)

    Pawson, David L.

    This report is part of a subseries entitled "Marine Flora and Fauna of the Northeastern United States" which is designed for use by biology students, biologists, biological oceanographers and informed laymen. Contents of this report include: (1) Introduction; (2) Morphology; (3) Systematic Characters; (4) Examination Procedures; (5)…

  17. Marine Flora and Fauna of the Northeastern United States. Sipuncula.

    Science.gov (United States)

    Cutler, Edward B.

    This report is part of a subseries entitled "Marine Flora and Fauna of the Northeastern United States" which is designed for use by biology students, biologists, biological oceanographers and informed laymen. Contents of this report include: (1) Introduction; (2) Key to Sipuncula (Peanut Worms); (3) Annotated Systematic List of Species;…

  18. Marine Flora and Fauna of the Northeastern United States. Copepoda: Lernaeopodidae and Sphyriidae.

    Science.gov (United States)

    Ho, Ju-Shey

    This report is part of a sub-series to aid biology students, biologists, biological oceanographers, and informed laymen in the identification and study of marine flora and fauna of the Northeastern United States. Contents of this report include: (1) Introduction; (2) Glossary; (3) Key to the marine lernaeopodoid copepods of the Northeastern United…

  19. Ciencia Marina/Negocio y Oficina. Libro del Profesor (Marine Science/Business & Office. Teacher's Guide). B7. CHOICE (Challenging Options in Career Education).

    Science.gov (United States)

    Mid-Hudson Migrant Education Center, New Paltz, NY.

    Written in Spanish, the guide comprises the sixth grade unit of a career education curriculum for migrant students. The unit covers 10 marine science, business, and office occupations: hydrographer, marine biologist, fish hatchery technician, boat builder, commercial diver, clerical worker, actuary, cashier, assistant bank manager, and computer…

  20. Arabidopsis protocols

    National Research Council Canada - National Science Library

    Martínez-Zapater, José M; Salinas, Julio

    1998-01-01

    ... the interest of geneticists and molecular biologists, not only from the plant field, but from other research fields needing a novel model system. In recent years, high expectations for Plant Biotechnology in the next century, together with the need for basic information in every area of plant biology, have served to mobilize resources and orient much new...