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Sample records for biologist marvin goldman

  1. Beginning with the Goldman Report

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    @@ Lin: In October 2003, U.S. Goldman Sachs Group. Inc. issued a report entitled "Dreaming with BRICs: The Path to 2050" that evoked huge response in the world. What interest us are not only the BRICs phenomenon, but also China on the list of BRICs. The report made high-sounding prediction of the economic prospects of Brazil, Russia and India. Its predict of China's economic prospect is also interesting. Therefore we attach importance to the report and conclusion thereof. Today we will hold a discussion on the report. Now let us begin our discussion.

  2. Marvin Charton - Correlation Analyst Par Excellence

    Directory of Open Access Journals (Sweden)

    John Shorter

    2005-01-01

    Full Text Available Abstract: Since the late 1950s Marvin Charton, physical organic chemist, of Pratt Institute, Brooklyn, New York has studied structure-property relationships through correlation analysis, and has become one of the leading authorities in this field.

  3. Cell scientist to watch - Marvin Tanenbaum.

    Science.gov (United States)

    2017-03-01

    Marvin Tanenbaum performed his undergraduate studies in Biomedical Sciences at the University of Amsterdam in The Netherlands. He obtained his PhD from Utrecht University in 2010 cum laude, having worked with René Medema on microtubule motor proteins. He won the Netherlands Association for Medical Education (NVMO) Oncology and Utrecht University Thesis awards, and moved to San Francisco with an EMBO long-term fellowship for his postdoctoral position in Ron Vale's laboratory at University of California, San Francisco (UCSF). There, Marvin shifted his focus to gene expression dynamics in living cells and developed the SunTag method to observe single-molecules in real time. He became a group leader at the Hubrecht Institute in Utrecht in 2015, supported by a European Research Council (ERC) starting grant.

  4. Something to die for: Rebutting the Mirkin & Goldman dilemma

    DEFF Research Database (Denmark)

    Christiansen, Ask Vest

    2016-01-01

    This essay investigates the soundness of the oft-repeated result of the Mirkin / Goldman dilemma. It says that approximately fifty per cent of all athletes should be willing to die if Olympic gold was at stake. The essay analyses the premises for this “well-known-fact” and traces the source...

  5. 75 FR 44031 - Goldman, Sachs & Co., et al.; Notice of Application and Temporary Order

    Science.gov (United States)

    2010-07-27

    ... Management International (``GSAMI''), Goldman Sachs Hedge Fund Strategies LLC (``GSHFS''), Commonwealth... global investment banking and securities firm. Goldman Sachs is registered as an investment adviser with... marketing materials used in connection with residential mortgage-related securities offerings by...

  6. Experimental Marvin Windshield Effects on Precipitation Records in Leadville, Colorado

    Science.gov (United States)

    Jarrett, Robert D.; Crow, Loren W.

    1988-01-01

    An evaluation of the Leadville, Colorado, precipitation records that include a reported record-breaking storm (and flood) at higher elevations in the Rocky Mountains has indicated that the use of an experimental Marvin windshield (designed to decrease the effects of wind on precipitation-gage catchment of snow during winter) resulted in substantially overregistered summer precipitation for 1919 to 1938. The July monthly precipitation for these years was over-registered by an average of 157 percent of the long-term July monthly precipitation at Leadville. The cause of the overregistration of precipitation was the almost 4-foot-top-diameter cone-shaped windshield that had the effect of 'funneling' hail and rain splash into the rain gage. Other nearby precipitation gages, which did not use this Marvin windshield, did not have this trend of increased precipitation for the same period. Streamflow records from the Leadville area also do not indicate an increase in streamflow from 1919 to 1938.

  7. Something to die for: Rebutting the Mirkin & Goldman dilemma

    DEFF Research Database (Denmark)

    Christiansen, Ask Vest

    2016-01-01

    This essay investigates the soundness of the oft-repeated result of the Mirkin / Goldman dilemma. It says that approximately fifty per cent of all athletes should be willing to die if Olympic gold was at stake. The essay analyses the premises for this “well-known-fact” and traces the source...... for the proposition. The essay concludes that there probably never was a real methodological sound survey and that scholars, journalists and politicians therefore should stop referencing the result. Athletes are NOT willing to die for a medal....

  8. Bringing Child Psychology to Religious Curricula: The Cautionary Tale of Goldman and Piaget.

    Science.gov (United States)

    Kay, William K.

    1996-01-01

    British researcher Ronald Goldman's attempts to apply Piagetian theory to children's interpretation of biblical narratives illustrates that the theory is ill suited to text interpretation. However, there are ways that child psychology can contribute to religious education. (SK)

  9. Marvin: A Heuristic Search Planner with Online Macro-Action Learning

    CERN Document Server

    Coles, A I; 10.1613/jair.2077

    2011-01-01

    This paper describes Marvin, a planner that competed in the Fourth International Planning Competition (IPC 4). Marvin uses action-sequence-memoisation techniques to generate macro-actions, which are then used during search for a solution plan. We provide an overview of its architecture and search behaviour, detailing the algorithms used. We also empirically demonstrate the effectiveness of its features in various planning domains; in particular, the effects on performance due to the use of macro-actions, the novel features of its search behaviour, and the native support of ADL and Derived Predicates.

  10. Systems biology: a biologist's viewpoint.

    Science.gov (United States)

    Bose, Biplab

    2013-12-01

    The debate over reductionism and antireductionism in biology is very old. Even the systems approach in biology is more than five decades old. However, mainstream biology, particularly experimental biology, has broadly sidestepped those debates and ideas. Post-genome data explosion and development of high-throughput techniques led to resurfacing of those ideas and debates as a new incarnation called Systems Biology. Though experimental biologists have co-opted systems biology and hailed it as a paradigm shift, it is practiced in different shades and understood with divergent meanings. Biology has certain questions linked with organization of multiple components and processes. Often such questions involve multilevel systems. Here in this essay we argue that systems theory provides required framework and abstractions to explore those questions. We argue that systems biology should follow the logical and mathematical approach of systems theory and transmogrification of systems biology to mere collection of higher dimensional data must be avoided. Therefore, the questions that we ask and the priority of those questions should also change. Systems biology should focus on system-level properties and investigate complexity without shying away from it.

  11. Marvin: MARtian Vehicular INvestigator A Proposal for a Long-Range Pressurized Rover

    Science.gov (United States)

    1999-01-01

    NASA is planning manned missions to Mars in the near future. In order to fully exploit the available time on the surface for exploration, a roving vehicle is necessary. A nine-member student design team from the Wichita State University Department of Aerospace Engineering developed the MARtian Vehicular INvestigator (MARVIN) a manned, pressurized, long distance rover. In order to meet the unique requirements for successful operation in the harsh Martian environment a four wheeled, rover was designed with a composite pressure vessel six meters long and 2.5 meters in diameter. The rover is powered by twin proton exchange membrane fuel cells which provide electricity to the drive motors and onboard systems. The MARVIN concept is expected to have a 1500 km range with a maximum speed of 25 km/hr and a 14-day endurance.

  12. Entrevista con Marcio Goldman, Museo Nacional de la Universidad Federal de Río de Janeiro

    Directory of Open Access Journals (Sweden)

    Giovanna Bacchiddu

    2015-09-01

    Full Text Available Marcio Goldman, doctor en Antropología por la Universidad Federal de Río de Janeiro y actualmente profesor del Museo Nacional de la UFRJ, se ha dedicado al estudio antropológico de las religiones afrobrasileñas y de la política. Ha sido profesor visitante en distintas universidades como la Universidad de São Paulo (USP, Universidad de Cabo Verde y Universidad de Chicago. Entre los libros publicados por Marcio Goldman encontramos Razão e Diferença. Afetividade, Racionalidade e Relativismo no Pensamento de Lévy-Bruhl (1994, Alguma Antropologia (1999 y Como Funciona a Democracia. Uma Teoria Etnográfica da Política (2006 —traducido al inglés como How Democracy Works. An Ethnographic Theory of Politics, 2013—. Su trabajo ha sido publicado en numerosas revistas como Social Analysis, Mana y Ethnos. Actualmente, Marcio Goldman lleva a cabo una investigación acerca de las cosmopolíticas de las religiones de matriz africana en Brasil a partir de un trabajo de campo realizado en un terreiro (templo de Candomblé en la ciudad de Ilhéus, en el sur del Estado de Bahía, el que resultará prontamente en un libro. Esta entrevista fue realizada en el marco de una visita al Departamento de Antropología de la Pontificia Universidad Católica de Chile.

  13. Amando de olhos abertos: Emma Goldman e o dissenso político nos EUA Loving with open eyes: Emma Goldman and the political dissent in the Unites States

    Directory of Open Access Journals (Sweden)

    Cecilia Azevedo

    2007-12-01

    Full Text Available Este artigo apresenta a trajetória de Emma Goldman, grande nome do anarquismo, pacifismo e feminismo nos EUA, procurando apresentá- la como uma representante da chamada tradição de dissenso neste país que, ao longo de toda sua história, tem disputado os sentidos a serem atribuídos aos ideais nacionais. Em meio à atual guerra no Iraque, a memória e o legado de Emma Goldman vêm sendo recuperados no embate político em torno do sentido do americanismo.This article presents the life of Emma Goldman, who played a central role in the history of anarchism, pacifism and feminism in the United States. In the present days, when a new war is taking place in Iraq, the memory and legacy of Emma Goldman are being reassessed amidst the debate over the political meaning of Americanism.

  14. The neurobiology of thought: the groundbreaking discoveries of Patricia Goldman-Rakic 1937-2003.

    Science.gov (United States)

    Arnsten, Amy F T

    2013-10-01

    Patricia S. Goldman-Rakic (1937-2003) transformed the study of the prefrontal cortex (PFC) and the neural basis of mental representation, the basic building block of abstract thought. Her pioneering research first identified the dorsolateral PFC (dlPFC) region essential for spatial working memory, and the extensive circuits of spatial cognition. She discovered the cellular basis of working memory, illuminating the dlPFC microcircuitry underlying spatially tuned, persistent firing, whereby precise information can be held "in mind": persistent firing arises from recurrent excitation within glutamatergic pyramidal cell circuits in deep layer III, while tuning arises from GABAergic lateral inhibition. She was the first to discover that dopamine is essential for dlPFC function, particularly through D1 receptor actions. She applied a host of technical approaches, providing a new paradigm for scientific inquiry. Goldman-Rakic's work has allowed the perplexing complexities of mental illness to begun to be understood at the cellular level, including atrophy of the dlPFC microcircuits subserving mental representation. She correctly predicted that impairments in dlPFC working memory activity would contribute to thought disorder, a cardinal symptom of schizophrenia. Ten years following her death, we look back to see how she inspired an entire field, fundamentally changing our view of cognition and cognitive disorders.

  15. Entropy for biologists an introduction to thermodynamics

    CERN Document Server

    Morowitz, Harold J

    2013-01-01

    Entropy for Biologists: An Introduction to Thermodynamics is an introductory book for people in the life sciences who wish to master the concepts of thermal physics without being forced to a degree and rate of symbol manipulation which is foreign to their patterns of thought. The book opens with a chapter on temperature, followed by separate chapters that discuss the concepts of energy, kinetic theory, total energy, the second law of thermodynamics, entropy, and probability and information theory. Subsequent chapters deal with statistical mechanics and its relation to thermodynamics, free-ener

  16. Which statistics should tropical biologists learn?

    Science.gov (United States)

    Loaiza Velásquez, Natalia; González Lutz, María Isabel; Monge-Nájera, Julián

    2011-09-01

    Tropical biologists study the richest and most endangered biodiversity in the planet, and in these times of climate change and mega-extinctions, the need for efficient, good quality research is more pressing than in the past. However, the statistical component in research published by tropical authors sometimes suffers from poor quality in data collection; mediocre or bad experimental design and a rigid and outdated view of data analysis. To suggest improvements in their statistical education, we listed all the statistical tests and other quantitative analyses used in two leading tropical journals, the Revista de Biología Tropical and Biotropica, during a year. The 12 most frequent tests in the articles were: Analysis of Variance (ANOVA), Chi-Square Test, Student's T Test, Linear Regression, Pearson's Correlation Coefficient, Mann-Whitney U Test, Kruskal-Wallis Test, Shannon's Diversity Index, Tukey's Test, Cluster Analysis, Spearman's Rank Correlation Test and Principal Component Analysis. We conclude that statistical education for tropical biologists must abandon the old syllabus based on the mathematical side of statistics and concentrate on the correct selection of these and other procedures and tests, on their biological interpretation and on the use of reliable and friendly freeware. We think that their time will be better spent understanding and protecting tropical ecosystems than trying to learn the mathematical foundations of statistics: in most cases, a well designed one-semester course should be enough for their basic requirements.

  17. State-transition diagrams for biologists.

    Science.gov (United States)

    Bersini, Hugues; Klatzmann, David; Six, Adrien; Thomas-Vaslin, Véronique

    2012-01-01

    It is clearly in the tradition of biologists to conceptualize the dynamical evolution of biological systems in terms of state-transitions of biological objects. This paper is mainly concerned with (but obviously not limited too) the immunological branch of biology and shows how the adoption of UML (Unified Modeling Language) state-transition diagrams can ease the modeling, the understanding, the coding, the manipulation or the documentation of population-based immune software model generally defined as a set of ordinary differential equations (ODE), describing the evolution in time of populations of various biological objects. Moreover, that same UML adoption naturally entails a far from negligible representational economy since one graphical item of the diagram might have to be repeated in various places of the mathematical model. First, the main graphical elements of the UML state-transition diagram and how they can be mapped onto a corresponding ODE mathematical model are presented. Then, two already published immune models of thymocyte behavior and time evolution in the thymus, the first one originally conceived as an ODE population-based model whereas the second one as an agent-based one, are refactored and expressed in a state-transition form so as to make them much easier to understand and their respective code easier to access, to modify and run. As an illustrative proof, for any immunologist, it should be possible to understand faithfully enough what the two software models are supposed to reproduce and how they execute with no need to plunge into the Java or Fortran lines.

  18. Central corneal thickness vs Goldman´ tonometry. Study in suspecting patients of Glaucoma.

    Directory of Open Access Journals (Sweden)

    Elsa E. Cabeza Martínez

    2010-04-01

    Full Text Available Measuring of the central corneal thickness through ultrasonic pachymetry, in several opportunities can contribute to diagnose glaucoma. The main objective of this research was to determine, the central corneal thickness in suspecting patients of having glaucoma.to check if it makes influence while taking the intraocular pressure with the Tonometer of Goldman, 328 eyes were studied out of the 164 patients who attended the glaucoma provincial appointment as suspecting of suffering from this pathology, who were included according to the study in the classification, of elaborated suspected in relation with this aspect. Taking into account:ocular hypertension without papillary alteration,papillary alteration without ocular hypertension,papillary alteration with ocular hypertension.It was carried out a measuring of the intraocular pressure and ultrasonic pachymetry to all eyes to know the central corneal thickness.Several variables were studied like, age, skin color, which were no significant. The thick cornea was predominant in the masculine sex and the thin ones in the femenine. Related to refractive deffects were predominant the thick cornea in myopic patients and in those suffering from hypermetropic. There was no relation among general illness associated and the central corneal thickness. It was predominant the eyes with normal central corneal thickness followed by those having thick cornea.The technological development plays an important role in the acute and precise diagnose of glaucoma, of all those patients sent to the provincial glaucoma appointment, because of being suspected less than 1/4 needed other studies after taking ultrasonic pachymetry.

  19. The Society of Brains: How Alan Turing and Marvin Minsky Were Both Right

    Science.gov (United States)

    Struzik, Zbigniew R.

    2015-04-01

    In his well-known prediction, Alan Turing stated that computer intelligence would surpass human intelligence by the year 2000. Although the Turing Test, as it became known, was devised to be played by one human against one computer, this is not a fair setup. Every human is a part of a social network, and a fairer comparison would be a contest between one human at the console and a network of computers behind the console. Around the year 2000, the number of web pages on the WWW overtook the number of neurons in the human brain. But these websites would be of little use without the ability to search for knowledge. By the year 2000 Google Inc. had become the search engine of choice, and the WWW became an intelligent entity. This was not without good reason. The basis for the search engine was the analysis of the ’network of knowledge’. The PageRank algorithm, linking information on the web according to the hierarchy of ‘link popularity’, continues to provide the basis for all of Google's web search tools. While PageRank was developed by Larry Page and Sergey Brin in 1996 as part of a research project about a new kind of search engine, PageRank is in its essence the key to representing and using static knowledge in an emergent intelligent system. Here I argue that Alan Turing was right, as hybrid human-computer internet machines have already surpassed our individual intelligence - this was done around the year 2000 by the Internet - the socially-minded, human-computer hybrid Homo computabilis-socialis. Ironically, the Internet's intelligence also emerged to a large extent from ‘exploiting’ humans - the key to the emergence of machine intelligence has been discussed by Marvin Minsky in his work on the foundations of intelligence through interacting agents’ knowledge. As a consequence, a decade and a half decade into the 21st century, we appear to be much better equipped to tackle the problem of the social origins of humanity - in particular thanks to the

  20. Correlations between the Lomonosov Ridge, Marvin Spur and adjacent basins of the Arctic Ocean based on seismic data

    Science.gov (United States)

    Langinen, A. E.; Lebedeva-Ivanova, N. N.; Gee, D. G.; Zamansky, Yu. Ya.

    2009-07-01

    Seismic profiles across the Lomonosov Ridge, Marvin Spur and adjacent basins, acquired near the North Pole by the drifting ice-station NP-28, provide a reflection image of the upper parts of the Ridge that is readily correlatable with those acquired by the Alfred Wegner Institute closer to the Siberian margin. A prominent flat-lying composite reflection package is seen in most parts of the Ridge at a few hundred meters below the sea bottom. Underlying reflections are variable in intensity and also in dip. The base of this reflection package is often accompanied by a sharp increase in P-velocity and defines a major angular discontinuity, referred to here as the Lomonosov Unconformity. The Arctic Coring Expedition (ACEX) cored the first c. 430 m section on the Lomonosov Ridge near the North Pole, in 2004 defining the deeper water character of the Neogene and the shallower water Paleogene sediments. These boreholes penetrated the composite reflection package towards the base of the hole and identified sediments (our Unit III) of late Paleocene and early Eocene age. Campanian beds at the very base of the hole were thought to be representative of the units below the Lomonosov Unconformity, but the P-velocity data suggest that this is unlikely. Correlation of the lithologies along the top of the Lomonosov Ridge and to the Marvin Spur indicates that the Marvin Spur is a sliver of continental crust closely related to, and rifted off the Ridge. This narrow (50 km wide) linear basement high can be followed into, beneath and across the Makarov Basin, supporting the interpretation that this Basin is partly resting on thinned continental crust. In the Makarov Basin, the Paleogene succession is much thicker than on the Ridge. Thus, the condensed, shallow water succession (with hiati) was deposited on the Ridge during rapid Eocene to Miocene subsidence of the Basin. In the Amundsen Basin, adjacent to the Lomonosov Ridge, the sedimentary successions thicken towards the Canadian

  1. The Biologist, the Psychologist, and the Environmental Crisis

    Science.gov (United States)

    Franke, Robert G.

    1971-01-01

    Considers the possibility that factors identified in the psychological writings of Eric Fromm, which neglect the fulfillment of human psychological needs may have helped induce the environmental crisis. States that biologists need to be aware of these factors when planning restorative and stabilizing strategies. (AL)

  2. Dr Jacob van der Land, marine biologist extraordinary

    NARCIS (Netherlands)

    Bruggen, van A.C.

    2001-01-01

    This contribution is an attempt to sketch the life and works of Dr Jacob van der Land, curator of worms and chief marine biologist of the National Museum of Natural History, on the occasion of his official retirement. Born in 1935, Jacob van der Land read biology at Leiden University (1958-1964), wh

  3. The descent of language. A conversation between two jobless biologists

    Directory of Open Access Journals (Sweden)

    Giovanni D'Angelo

    2013-06-01

    Full Text Available Seen from the perspective of a biologist, the issue of the origin of language contains an inherent ambiguity. On the one hand, one might think to explore the cognitive features or even the anatomical structures related to communication through the peculiar medium called verbal language, a characteristic property emergent among the Homo sapiens. On the other hand, if one decides to restrict oneself to the formal definition of language as a system of signs for encoding information, then, the human‐specific nature of language becomes less convincing and the temptation to look into non ‐ human languages allows a provocative question. Was human verbal language an invention or a discovery? In the following two biologists informally discuss about the concept of non‐ verbal biological languages.

  4. Expanding the Biologist's Toolkit with CRISPR-Cas9.

    Science.gov (United States)

    Sternberg, Samuel H; Doudna, Jennifer A

    2015-05-21

    Few discoveries transform a discipline overnight, but biologists today can manipulate cells in ways never possible before, thanks to a peculiar form of prokaryotic adaptive immunity mediated by clustered regularly interspaced short palindromic repeats (CRISPR). From elegant studies that deciphered how these immune systems function in bacteria, researchers quickly uncovered the technological potential of Cas9, an RNA-guided DNA cleaving enzyme, for genome engineering. Here we highlight the recent explosion in visionary applications of CRISPR-Cas9 that promises to usher in a new era of biological understanding and control.

  5. Determining K+ channel activation curves from K+ channel currents often requires the Goldman-Hodgkin-Katz equation

    Directory of Open Access Journals (Sweden)

    john r Clay

    2009-12-01

    Full Text Available Potassium ion current in nerve membrane, IK, has traditionally been described by IK = gK(V-EK, where gK is the K ion conductance, V is membrane potential, and EK is the K+ Nernst potential. This description has been unchallenged by most investigators in neuroscience since its introduction almost sixty years ago. The problem with the IK ~ (V-EK proportionality is that it is inconsistent with the unequal distribution of K ions in the intra- and extracellular bathing media. Under physiological conditions the intracellular K+ concentraion is significantly higher than the extracellular concentration. Consequently, the slope conductance at potentials positive to EK cannot be the same as that for potentials negative to EK, as the linear proportionality requires. Instead IK has a non-linear dependence on (V-EK which is well described by the Goldman-Hodgkin-Katz equation. The implications of this result for K+ channel gating and membrane excitability are reviewed in this report.

  6. Improving interactions between animal rights groups and conservation biologists.

    Science.gov (United States)

    Perry, Dan; Perry, Gad

    2008-02-01

    Invasive species are often considered to be a major threat to biodiversity, leading conservation biologists to often recommend their complete eradication. Animal rights groups typically categorically oppose killing animals, and their opposition has brought eradication attempts of gray squirrels in northern Italy (Europe) and mute swans in Vermont to a halt. As a result native red squirrels may disappear from Europe and ecosystem-wide impacts are expected to be caused by the swan. In contrast, cooperation between managers and animal rights groups has resulted in a successful control program for feral pigs in Fort Worth, Texas (U.S.A.). The philosophical differences between animal rights and conservation biologists' views make cooperation seem unlikely, yet documented cases of cooperation have been beneficial for both groups. We recommend that managers dealing with invasive species should consult with social scientists and ethicists to gain a better understanding of the implications of some of their policy decisions. In addition, we recommend that animal rights groups do more to support alternatives to lethal control, which are often excluded by economic limitations. Prevention of arrival of invasive species via application of the precautionary principle may be an especially productive avenue for such collaboration because it fits the goals and values of both groups.

  7. Reinventing College Physics for Biologists: Explicating an epistemological curriculum

    CERN Document Server

    Redish, Edward F

    2008-01-01

    The University of Maryland Physics Education Research Group (UMd-PERG) carried out a five-year research project to rethink, observe, and reform introductory algebra-based (college) physics. This class is one of the Maryland Physics Department's large service courses, serving primarily life-science majors. After consultation with biologists, we re-focused the class on helping the students learn to think scientifically -- to build coherence, think in terms of mechanism, and to follow the implications of assumptions. We designed the course to tap into students' productive conceptual and epistemological resources, based on a theoretical framework from research on learning. The reformed class retains its traditional structure in terms of time and instructional personnel, but we modified existing best-practices curricular materials, including Peer Instruction, Interactive Lecture Demonstrations, and Tutorials. We provided class-controlled spaces for student collaboration, which allowed us to observe and record stud...

  8. A Biologist's Field Guide to Multiplexed Quantitative Proteomics.

    Science.gov (United States)

    Bakalarski, Corey E; Kirkpatrick, Donald S

    2016-05-01

    High-throughput genomic and proteomic studies have generated near-comprehensive catalogs of biological constituents within many model systems. Nevertheless, static catalogs are often insufficient to fully describe the dynamic processes that drive biology. Quantitative proteomic techniques address this need by providing insight into closely related biological states such as the stages of a therapeutic response or cellular differentiation. The maturation of quantitative proteomics in recent years has brought about a variety of technologies, each with their own strengths and weaknesses. It can be difficult for those unfamiliar with this evolving landscape to match the experiment at hand with the best tool for the job. Here, we outline quantitative methods for proteomic mass spectrometry and discuss their benefits and weaknesses from the perspective of the biologist aiming to generate meaningful data and address mechanistic questions.

  9. Engineers are from PDMS-land, Biologists are from Polystyrenia.

    Science.gov (United States)

    Berthier, Erwin; Young, Edmond W K; Beebe, David

    2012-04-07

    As the integration of microfluidics into cell biology research proceeds at an ever-increasing pace, a critical question for those working at the interface of both disciplines is which device material to use for a given application. While PDMS and soft lithography methods offer the engineer rapid prototyping capabilities, PDMS as a material has characteristics that have known adverse effects on cell-based experiments. In contrast, while polystyrene (PS), the most commonly used thermoplastic for laboratory cultureware, has provided decades of grounded and validated research conclusions in cell behavior and function, PS as a material has posed significant challenges in microfabrication. These competing issues have forced microfluidics engineers and biologists to make compromises in how they approach specific research questions, and furthermore, have attenuated the impact of microfluidics on biological research. In this review, we provide a comparison of the attributes of PDMS and PS, and discuss reasons for their popularity in their respective fields. We provide a critical evaluation of the strengths and limitations of PDMS and PS in relation to the advancement and future impact on microfluidic cell-based studies and applications. We believe that engineers have a responsibility to overcome any challenges associated with microfabrication, whether with PS or other materials, and that engineers should provide options and solutions that assist biologists in their experimental design. Our goal is not to advocate for any specific material, but provide guidelines for researchers who desire to choose the most suitable material for their application, and suggest important research directions for engineers working at the interface between microfabrication technology and biological application.

  10. Steroid use and human performance: Lessons for integrative biologists.

    Science.gov (United States)

    Husak, Jerry F; Irschick, Duncan J

    2009-10-01

    While recent studies have begun to address how hormones mediate whole-animal performance traits, the field conspicuously lags behind research conducted on humans. Recent studies of human steroid use have revealed that steroid use increases muscle cross-sectional area and mass, largely due to increases in protein synthesis, and muscle fiber hypertrophy attributable to an increased number of satellite cells and myonuclei per unit area. These biochemical and cellular effects on skeletal muscle morphology translate into increased power and work during weight-lifting and enhanced performance in burst, sprinting activities. However, there are no unequivocal data that human steroid use enhances endurance performance or muscle fatigability or recovery. The effects of steroids on human morphology and performance are in general consistent with results found for nonhuman animals, though there are notable discrepancies. However, some of the discrepancies may be due to a paucity of comparative data on how testosterone affects muscle physiology and subsequent performance across different regions of the body and across vertebrate taxa. Therefore, we advocate more research on the basic relationships among hormones, morphology, and performance. Based on results from human studies, we recommend that integrative biologists interested in studying hormone regulation of performance should take into account training, timing of administration, and dosage administered when designing experiments or field studies. We also argue that more information is needed on the long-term effects of hormone manipulation on performance and fitness.

  11. 金融衍生品案例研究:高盛金融欺诈案%Case Study of Financial Derivatives: Fraud Action of Goldman Sachs

    Institute of Scientific and Technical Information of China (English)

    李欣婷; 闫妍; 薛欣

    2012-01-01

    The United States Securities and Exchange Commission brings the securities fraud action against Goldman Sachs, for making materially misleading statements and commissions in connection with a synthetic eollateralized debt obligation ("CDO") Goldman Sachs structured and marketed to investors. This CDO product whose name is ABACUS 2007-AC1 led to a great loss to the investors. This paper mainly analyzes the structures and risk features of three derivative products including RMBS, CDS and CDO. Based on the valuation formula, the reason of ABACUS 2007-AC1 depreciation is explained.%高盛集团因金融欺诈被美国证券交易委员会起诉,原因是高盛集团在销售一款合成担保债务凭证ABACUS2007-AC1时有误导性陈述,导致投资者巨额亏损。本文重点对案例中涉及的金融衍生品——RMBS、CDS和CDO的结构和风险特征进行分析,并结合CDO定价公式,对ABACUS2007-AC1的价值下跌进行定量的分析。

  12. Professor Darleane C. Hoffman, Senior Advisor & Charter Director Seaborg Institute for Transactinium Science Livermore, California and Dr Marvin Hoffman accompanied by Professor Heinz Gäggeler, University of Bern and Paul Scherrer Institut Villigen.

    CERN Multimedia

    Maximilien Brice

    2001-01-01

    Photo 02 : Visit of Professor Darleane C. Hoffman, Senior Advisor & Charter Director, Seaborg Institute for Transactinium Science, Livermore, California with (from left to right) Dr Mats Lindroos, ISOLDE Technical Coordinator; Professor Heinz Gäggeler, University of Bern and Paul Scherrer Institute Villigen, and Dr Marvin Hoffman.

  13. A chemist and biologist talk to each other about caged neurotransmitters

    Directory of Open Access Journals (Sweden)

    Graham C.R. Ellis-Davies

    2013-01-01

    Full Text Available Caged compounds are small organic molecules that can be photoactivated with brief pulses of light. They are widely used to study a great variety of biological processes by physiologists, cell biologists and neuroscientists. Initially made and invented by biologists in the late 1970s, they are now made mostly by chemists, often without any dialogue with the end users, the biologists. The idea for this review is to stimulate interaction between the two communities to further the creative development and application of these powerful optical probes.

  14. Career Choices by Biologists: A Case Study of Destinations of Graduates in Marine Biology and Zoology, 1986-1998.

    Science.gov (United States)

    Gill, Margaret E.; Golding, David W.

    2001-01-01

    Reports on a study tracking marine biologists' and zoologists' employment status between the years of 1986 and 1998. Suggests that despite the increase in university class sizes, able and well-trained biologists enjoy good career prospects. (Author/YDS)

  15. Young CAS biologist gets five-year grant from Howard Hughes Medical Institute

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Dr. TANG Chun, an outstanding young biologist from the CAS Wuhan Institute of Physics and Mathematics (WIPM) was announced in January 2012 to have won the first International Early Career Award from Howard Hughes Medical Institute with a five-year grant totaling up to 650,000 US dollars. Dr. Tang is an expert in using novel nuclear magnetic resonance methods to study the behavior and function of proteins,

  16. Educational background and professional participation by federal wildlife biologists: Implications for science, management, and The Wildlife Society

    Science.gov (United States)

    Schmutz, J.A.

    2002-01-01

    Over 2,000 people are employed in wildlife biology in the United States federal government. The size of this constituency motivated me to examine the amount of formal education federal biologists have received and the extent of continuing education they undertake by reading journals or attending scientific meetings. Most federal biologists who are members of The Wildlife Society (TWS) have a graduate degree. However, one-third have only a Bachelor of Science degree, despite the current trend toward hiring people with graduate degrees. Most federal biologists are not research biologists. Numbers of journals subscribed to was positively related to educational level. Less than one-third of all wildlife biologists employed by the United States Fish and Wildlife Service are members of TWS or subscribe to any of its journals. In contrast, the majority of presenters at the TWS 2000 Annual Conference were research biologists and members of TWS. The failure of many federal wildlife biologists to read scientific literature or attend professional meetings indicates a failure to promote the importance of continuing education in the federal workplace. I identify 2 potential adverse impacts of this failing: an inability to recognize important and relevant scientific contributions and an ineffectiveness in carrying out adaptive management.

  17. Fighting for life: Religion and science in the work of fish and wildlife biologists

    Science.gov (United States)

    Geffen, Joel Phillip

    Philosophers, historians, and sociologists of science have argued that it is impossible to separate fact from value. Even so, Americans generally demand that scientists be "objective." No bias is permitted in their work. Religious motivations in particular are widely considered anathema within the halls of science. My dissertation addresses both theoretical and practical aspects concerning objectivity in science through an examination of fish and wildlife biologists. I hypothesized that they use the language of objective science as a tool to convince others to protect habitats and species. Further, I claimed that this "rhetoric of science" is employed either consciously or unconsciously on behalf of personal values, and that religious and/or spiritual values figure significantly among these. Regarding the issue's practical applications, I argued in support of Susan Longino's assertion that while subjective influences exist in science, they do not necessarily indicate that objectivity has been sacrificed. My primary methodology is ethnographic. Thirty-five biologists working in the Pacific Northwest were interviewed during the course of summer 2001. Participant ages ranged from 23 to 78. Both genders were represented, as were various ethnic and cultural backgrounds, including Native American. I used a questionnaire to guide respondents through a consistent set of open-ended queries. I organized their answers under four categories: the true, the good, the beautiful, and the holy. The first three were borrowed from the theoretical writings of philosopher Immanuel Kant. The last came from Rudolf Otto's theological work. These categories provided an excellent analytical framework. I found that the great majority of fish and wildlife biologists strive for objectivity. However, they are also informed by powerful contextual values. These are derived from environmental ethics, aesthetic preferences pertaining to ecosystem appearance and function, and visceral experiences of

  18. Preeminent Biologist Joins CAS to Lead a New Research Center in Shanghai

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Dr. ZHU Jiankang, an internationally renowned plant cell biologist and member of the US National Academy of Sciences, will work as Director of the Shanghai Center for Plant Stress Biology, which was officially inaugurated on April 28, 2012 in suburban Shanghai. Before he joined CAS through a key talent recruitment program sponsored by the Chinese government called the "Thousand Talents Program", Dr. ZHU had worked for many universities in the world and carried out leading innovative research on genetic and epigenetic mechanisms of plant responses to adverse environments such as salinity, drought and low temperature.

  19. News UK public libraries offer walk-in access to research Atoms for Peace? The Atomic Weapons Establishment and UK universities Students present their research to academics: CERN@school Science in a suitcase: Marvin and Milo visit Ethiopia Inspiring telescopes A day for everyone teaching physics 2014 Forthcoming Events

    Science.gov (United States)

    2014-05-01

    UK public libraries offer walk-in access to research Atoms for Peace? The Atomic Weapons Establishment and UK universities Students present their research to academics: CERN@school Science in a suitcase: Marvin and Milo visit Ethiopia Inspiring telescopes A day for everyone teaching physics 2014 Forthcoming Events

  20. CWM Global Search—The Internet Search Engine for Chemists and Biologists

    Directory of Open Access Journals (Sweden)

    Hans-Jürgen Himmler

    2010-12-01

    Full Text Available CWM Global Search is a meta-search engine allowing chemists and biologists to search the major chemical and biological databases on the Internet, by structure, synonyms, CAS Registry Numbers and free text. A meta-search engine is a search tool that sends user requests to several other search engines and/or databases and aggregates the results into a single list or displays them according to their source [1]. CWM Global Search is a web application that has many of the characteristics of desktop applications (also known as Rich Internet Application, RIA, and it runs on both Windows and Macintosh platforms. The application is one of the first RIA for scientists. The application can be started using the URL http://cwmglobalsearch.com/gsweb.

  1. What in silico molecular docking can do for the `bench-working biologists'

    Indian Academy of Sciences (India)

    Marius Mihăşan

    2012-12-01

    Required by an increasing amount of scientists, the in silico docking field is in full expansion, new algorithms and methods appearing at an exponential rate. The sheer range of available programs is overwhelming for the bench-working biologist, which is often discouraging by the lack of a graphical user interface, good user manual or literature to validate a given program. This mini-review attempts to present the docking problem and available solutions from a non-bioinformatician point of view and makes a selection of the available servers and programs. These tools are evaluated from several points of view, as numbers of citations, ease of usage and computer requirements. Finally, the capabilities and limitations as well as specific applications of in silico docking techniques are presented.

  2. BioLogistics and the Struggle for Efficiency: Concepts and Perspectives

    CERN Document Server

    Helbing, Dirk; Diez, Stefan; Peters, Karsten; Kalaidzidis, Yannis; Padberg, Kathrin; Lammer, Stefan; Johansson, Anders; Breier, Georg; Schulze, Frank; Zerial, Marino; 10.1142/S0219525909002374

    2010-01-01

    The growth of world population, limitation of resources, economic problems and environmental issues force engineers to develop increasingly efficient solutions for logistic systems. Pure optimization for efficiency, however, has often led to technical solutions that are vulnerable to variations in supply and demand, and to perturbations. In contrast, nature already provides a large variety of efficient, flexible and robust logistic solutions. Can we utilize biological principles to design systems, which can flexibly adapt to hardly predictable, fluctuating conditions? We propose a bio-inspired "BioLogistics" approach to deduce dynamic organization processes and principles of adaptive self-control from biological systems, and to transfer them to man-made logistics (including nanologistics), using principles of modularity, self-assembly, self-organization, and decentralized coordination. Conversely, logistic models can help revealing the logic of biological processes at the systems level.

  3. GeneNotes – A novel information management software for biologists

    Directory of Open Access Journals (Sweden)

    Wong Wing H

    2005-02-01

    Full Text Available Abstract Background Collecting and managing information is a challenging task in a genome-wide profiling research project. Most databases and online computational tools require a direct human involvement. Information and computational results are presented in various multimedia formats (e.g., text, image, PDF, word files, etc., many of which cannot be automatically processed by computers in biologically meaningful ways. In addition, the quality of computational results is far from perfect and requires nontrivial manual examination. The timely selection, integration and interpretation of heterogeneous biological information still heavily rely on the sensibility of biologists. Biologists often feel overwhelmed by the huge amount of and the great diversity of distributed heterogeneous biological information. Description We developed an information management application called GeneNotes. GeneNotes is the first application that allows users to collect and manage multimedia biological information about genes/ESTs. GeneNotes provides an integrated environment for users to surf the Internet, collect notes for genes/ESTs, and retrieve notes. GeneNotes is supported by a server that integrates gene annotations from many major databases (e.g., HGNC, MGI, etc.. GeneNotes uses the integrated gene annotations to (a identify genes given various types of gene IDs (e.g., RefSeq ID, GenBank ID, etc., and (b provide quick views of genes. GeneNotes is free for academic usage. The program and the tutorials are available at: http://bayes.fas.harvard.edu/genenotes/. Conclusions GeneNotes provides a novel human-computer interface to assist researchers to collect and manage biological information. It also provides a platform for studying how users behave when they manipulate biological information. The results of such study can lead to innovation of more intelligent human-computer interfaces that greatly shorten the cycle of biology research.

  4. The Washington Biologists' Field Club : Its members and its history (1900-2006)

    Science.gov (United States)

    Perry, M.C.

    2007-01-01

    This book is based on the interesting one-hundred-plus-year history of the Club and its members. Plummers Island and the historic cabin on the Island have served as a common meeting area where the Club members have conducted research and held many social activities for over a century. The history has been written and revised over the years by members, and the biographical sketches also have been collected and written by the members. The Club was formed in 1900 and incorporated as a society in 1901 for scientists in the Washington, D.C., area. In recent years the Club has sponsored research by many non-member local scientists with grants totaling over $305,000. The cumulative total of 267 members represents all branches of natural science, with a strong emphasis on biology as the Club name indicates. In addition to the biologists there have been famous naturalists (e.g., John Burroughs), high-level administrators (e.g., Ira Gabrielson), and well-known artists (e.g., Roger Tory Peterson). Most members have been biological scientists, working for agencies in the Washington, D.C., area, who have published many articles and books dealing with biology and related subjects. The book is publIshed mainly for the benefit of the living Club members and for relatives of the deceased members. The members hope that the book will find its way into libraries across the country and that in the future, persons interested in some of the pioneer scientists, in the various professional areas of science, can obtain biographical information from a well-documented source. Most of the 542 illustrations of the members, cabin, and the Island have not been published previously. It is hopeful that the biographical sketches, pictures, and other information presented in this book can generate new information for future publications and for the website of the Washington Biologists' Field Club, which is updated frequently.

  5. WE-G-213-02: The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who Were They and What Did They Do?

    Energy Technology Data Exchange (ETDEWEB)

    Rothenberg, L. [Memorial Sloan-Kettering Cancer Center (United States)

    2015-06-15

    Roentgen and the Birth of Modern Medical Physics – Perry Sprawls Wilhelm Roentgen is well known for his discovery of x-radiation. What is less known and appreciated is his intensive research following the discovery to determine the characteristics of the “new kind of radiation” and demonstrate its great value for medical purposes. In this presentation we will imagine ourselves in Roentgen’s mind and follow his thinking, including questions and doubts, as he designs and conducts a series of innovative experiments that provided the foundation for the rapid growth of medical physics. Learning Objectives: Become familiar with the personal characteristics and work of Prof. Roentgen that establishes him as an inspiring model for the medical physics profession. Observe the thought process and experiments that determined and demonstrated the comprehensive characteristics of x-radiation. The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who were they and what did they do? – Lawrence N. Rothenberg William David Coolidge (1873–1975) William Coolidge was born in Hudson, NY in 1873. He obtained his BS at the Massacusetts Institute of Technology in 1896. Coolidge then went to the University of Leipzig, Germany for graduate study with physicists Paul Drude and Gustave Wiedemann and received a Ph.D. in 1899. While in Germany he met Wilhelm Roentgen. Coolidge returned to the US to teach at MIT where he was associated with Arthur A. Noyes of the Chemistry Department, working on the electrical conductivity of aqueous solutions. Willis R. Whitney, under whom Coolidge had worked before going to Germany, became head of the newly formed General Electric Research Laboratory and he invited Coolidge to work with him. In 1905, Coolidge joined the staff of the GE laboratory and was associated with it for the remainder of his life. He developed ductile tungsten filaments to replace fragile carbon filaments as the material for electric light

  6. WE-G-213-00: History Symposium: Radiological Physics Pioneers: Roentgen and the AAPM Award Eponyms - William Coolidge, Edith Quimby, and Marvin Williams - Who Were They and What Did They Do?

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2015-06-15

    Roentgen and the Birth of Modern Medical Physics – Perry Sprawls Wilhelm Roentgen is well known for his discovery of x-radiation. What is less known and appreciated is his intensive research following the discovery to determine the characteristics of the “new kind of radiation” and demonstrate its great value for medical purposes. In this presentation we will imagine ourselves in Roentgen’s mind and follow his thinking, including questions and doubts, as he designs and conducts a series of innovative experiments that provided the foundation for the rapid growth of medical physics. Learning Objectives: Become familiar with the personal characteristics and work of Prof. Roentgen that establishes him as an inspiring model for the medical physics profession. Observe the thought process and experiments that determined and demonstrated the comprehensive characteristics of x-radiation. The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who were they and what did they do? – Lawrence N. Rothenberg William David Coolidge (1873–1975) William Coolidge was born in Hudson, NY in 1873. He obtained his BS at the Massacusetts Institute of Technology in 1896. Coolidge then went to the University of Leipzig, Germany for graduate study with physicists Paul Drude and Gustave Wiedemann and received a Ph.D. in 1899. While in Germany he met Wilhelm Roentgen. Coolidge returned to the US to teach at MIT where he was associated with Arthur A. Noyes of the Chemistry Department, working on the electrical conductivity of aqueous solutions. Willis R. Whitney, under whom Coolidge had worked before going to Germany, became head of the newly formed General Electric Research Laboratory and he invited Coolidge to work with him. In 1905, Coolidge joined the staff of the GE laboratory and was associated with it for the remainder of his life. He developed ductile tungsten filaments to replace fragile carbon filaments as the material for electric light

  7. Measuring, interpreting, and responding to changes in coral reefs: A challenge for biologists, geologist, and managers

    Science.gov (United States)

    Rogers, Caroline S.; Miller, Jeff; Hubbard, Dennis K.; Rogers, Caroline S.; Lipps, Jere H.; Stanley, George D.

    2016-01-01

    What, exactly, is a coral reef? And how have the world’s reefs changed in the last several decades? What are the stressors undermining reef structure and function? Given the predicted effects of climate change, do reefs have a future? Is it possible to “manage” coral reefs for resilience? What can coral reef scientists contribute to improve protection and management of coral reefs? What insights can biologists and geologists provide regarding the persistence of coral reefs on a human timescale? What is reef change to a biologist… to a geologist?Clearly, there are many challenging questions. In this chapter, we present some of our thoughts on monitoring and management of coral reefs in US national parks in the Caribbean and western Atlantic based on our experience as members of monitoring teams. We reflect on the need to characterize and evaluate reefs, on how to conduct high-quality monitoring programs, and on what we can learn from biological and geological experiments and investigations. We explore the possibility that specific steps can be taken to “manage” coral reefs for greater resilience.

  8. From glass flowers to computer games: Examining the emergent media practices of plant biologists

    Science.gov (United States)

    Reitmeyer, Morgan

    The goal of this project is to begin investigating the emergent media practices of current academic disciplines. This dissertation posits that Writing Across the Curriculum (WAC) scholars have investigated new media use in undergraduate pedagogy, and to some extent the practices of graduate students. However, WAC scholars have yet to try to understand how Writing in the Disciplines (WID) is being impacted by emergent media. The gap might be, in part, accounted for by the complexity of researching disciplinary writing compounded by the complexity of researching new media. However, in order to both design effective undergraduate curriculum and partner with peers across the discipline, this research must take place. This dissertation proposes a mixed method process, consisting of textual analysis, interviews and observations, in order to understand emergent media writing in the disciplines. Specifically, this research focuses on the practices of plant biologists online publication, online professionalization, and changing use of databases. This preliminary study reflects on the research practices that could be used to gather this information, as well what rhetoric and composition scholars have to gain from this type of difficult work.

  9. Speeding up ecological and evolutionary computations in R; essentials of high performance computing for biologists.

    Science.gov (United States)

    Visser, Marco D; McMahon, Sean M; Merow, Cory; Dixon, Philip M; Record, Sydne; Jongejans, Eelke

    2015-03-01

    Computation has become a critical component of research in biology. A risk has emerged that computational and programming challenges may limit research scope, depth, and quality. We review various solutions to common computational efficiency problems in ecological and evolutionary research. Our review pulls together material that is currently scattered across many sources and emphasizes those techniques that are especially effective for typical ecological and environmental problems. We demonstrate how straightforward it can be to write efficient code and implement techniques such as profiling or parallel computing. We supply a newly developed R package (aprof) that helps to identify computational bottlenecks in R code and determine whether optimization can be effective. Our review is complemented by a practical set of examples and detailed Supporting Information material (S1-S3 Texts) that demonstrate large improvements in computational speed (ranging from 10.5 times to 14,000 times faster). By improving computational efficiency, biologists can feasibly solve more complex tasks, ask more ambitious questions, and include more sophisticated analyses in their research.

  10. The Plant Detectives: innovative undergraduate teaching to inspire the next generation of plant biologists

    Directory of Open Access Journals (Sweden)

    Elizabeth Ann Beckmann

    2015-09-01

    Full Text Available Encouraging more students to embrace plant science research is an urgent global priority. We have evolved a second year undergraduate course from a standard lecture/practical format into an innovative research-led learning design that gives students hands-on experience of cutting-edge plant science research and specialist instrumentation. By making tangible the links between plant genetics, biochemistry, physiology and function, the active learning curriculum extends students to their limits, and gives them insights into the multi-faceted nature of plant science research. Using genetically-mapped mutants of Arabidopsis thaliana, we challenge our students to apply their conceptual learning immediately to identify 'unknown' genetic mutations affecting plant form and function. By exposing students early in their student careers to the challenges, rigours and excitement of plant science research, we have helped them grow quickly into astute researchers who truly deserve the title 'Plant Detectives'. Many have become motivated to continue their studies as plant biologists in research-focused honours (pre-doctoral and doctoral programs.

  11. Cognitive empathy in inter-disciplinary research: the contrasting attitudes of plant breeders and molecular biologists towards rice

    Indian Academy of Sciences (India)

    E Haribabu

    2000-12-01

    I draw attention to the perceptions of and interactions between molecular biologists and scientists engaged in plant breeding in India, who have been attempting to employ molecular biology tools to understand and intervene to improve the rice crop. The present essay suggests that the concept of cognitive empathy is crucial for enabling basic scientists and applied scientists to begin to understand phenomena from the point of view of the other and from the point of view of society at large, and in arriving at solutions that are scientifically feasible and socially acceptable. Socialization into disciplinary cultures, organizational factors and individual anxieties seem to inhibit inter-disciplinary collaboration. The majority of rice breeders and a small group of molecular biologists emphasize the relative merits of marker-assisted selection (MAS) in the near term vis-à-vis the currently controversial transgenic approach for rice crop improvement in India.

  12. Quantum Physics for Scientists and Technologists Fundamental Principles and Applications for Biologists, Chemists, Computer Scientists, and Nanotechnologists

    CERN Document Server

    Sanghera, Paul

    2011-01-01

    Presenting quantum physics for the non-physicists, Quantum Physics for Scientists and Technologists is a self-contained, cohesive, concise, yet comprehensive, story of quantum physics from the fields of science and technology, including computer science, biology, chemistry, and nanotechnology. The authors explain the concepts and phenomena in a practical fashion with only a minimum amount of math. Examples from, and references to, computer science, biology, chemistry, and nanotechnology throughout the book make the material accessible to biologists, chemists, computer scientists, and non-techn

  13. Falling through the cracks: shortcomings in the collaboration between biologists and veterinarians and their consequences for wildlife.

    Science.gov (United States)

    Cattet, Marc R L

    2013-01-01

    Although biologists and veterinarians have shown considerable success in working together to address wildlife-related issues, including disease, chemical immobilization, reproductive biology, and conservation biology, examples of shared efforts to evaluate and ensure the welfare of study animals are mostly absent. I present the case that this deficiency arises primarily from a lack of mutual understanding between fields with respect to the other's training and experience in addressing animal welfare issues. In effect, each assumes that the final word on animal welfare rests with the other. The reality is, however, that neither field contains the knowledge and skills required to address animal welfare concerns alone. Nevertheless, wildlife researchers are increasingly encountering difficulties conducting research on wild animals because of opposition from stakeholders on the basis of animal welfare concerns. Further, a growing number of articles in the peer-reviewed scientific literature are reporting on potential biases in research results developing from the welfare impacts of widely used techniques, including methods of capturing and marking wildlife. By viewing animal welfare as a shared responsibility and combining their knowledge and skills, wildlife biologists and veterinarians have an opportunity to reform "invasive" wildlife research in a manner that is less harmful to the animals being studied, less likely to bias research results, and less objectionable to the stakeholders who ultimately influence or make decisions on how wildlife research is conducted.

  14. Physical biologists and biological physicists: combining biology and physics in research on the effects of noise on aquatic life.

    Science.gov (United States)

    Cato, Douglas H

    2012-01-01

    Research in aquatic bioacoustics and the effects of noise is interdisciplinary and to be effective requires a collaboration of experts from all the fields involved. The full range of expertise is needed for adequate understanding of the processes involved, adequate experimental design, analysis and interpretation, and adequate knowledge of the research already published. The biologists need to understand how physicists work and make allowance, and vice versa. Both need to understand that the other will not be familiar with their practices and approach and that there will be a certain amount of negotiation and education on both sides.However, the best reason to develop collaborations with other experts in interdisciplinary research is that it is such a rewarding experience from the insights it provides into other disciplines and from the opportunity to do really effective and very significant research, well beyond what the individuals might have achieved on their own.

  15. A biologist's guide to de novo genome assembly using next-generation sequence data: A test with fungal genomes.

    Science.gov (United States)

    Haridas, Sajeet; Breuill, Colette; Bohlmann, Joerg; Hsiang, Tom

    2011-09-01

    We offer a guide to de novo genome assembly using sequence data generated by the Illumina platform for biologists working with fungi or other organisms whose genomes are less than 100Mb in size. The guide requires no familiarity with sequencing assembly technology or associated computer programs. It defines commonly used terms in genome sequencing and assembly; provides examples of assembling short-read genome sequence data for four strains of the fungus Grosmannia clavigera using four assembly programs; gives examples of protocols and software; and presents a commented flowchart that extends from DNA preparation for submission to a sequencing center, through to processing and assembly of the raw sequence reads using freely available operating systems and software.

  16. A Response to "BIO 2010: Transforming Undergraduate Education for Future Research Biologists," from the Perspective of the Biochemistry and Molecular Biology Major Program at Kenyon College

    Science.gov (United States)

    Slonczewski, Joan L.; Marusak, Rosemary

    2004-01-01

    The National Research Council completed a major study of undergraduate biology education, "BIO 2010-Transforming Undergraduate Education For Future Research Biologists (BIO 2010)," funded by the Howard Hughes Medical Institute and the National Institutes of Health. The "BIO 2010" report recommends that biology pedagogy should use an…

  17. Biologists Bridging Science and the Conservation Movement : The Rise of Nature Conservation and Nature Management in the Netherlands, 1850-1950

    NARCIS (Netherlands)

    van der Windt, Henny J.

    2012-01-01

    This paper investigates the importance and various roles of amateur naturalists and biologists in the conservation movement between 1850 and 1950, in particular in the Netherlands. It is concluded that biological sciences were important resources for Dutch nature conservation, although the extent of

  18. Zoonotic disease risk and prevention practices among biologists and other wildlife workers--results from a national survey, US National Park Service, 2009.

    Science.gov (United States)

    Bosch, Stacey A; Musgrave, Karl; Wong, David

    2013-07-01

    In 2007, a National Park Service (NPS) biologist died from pneumonic plague after unprotected exposure to an infected mountain lion. This incident increased awareness of occupational zoonotic disease transmission and prompted an assessment of employees who handle wildlife. During April-June 2009, we conducted a national online survey of NPS biologists and other wildlife workers to assess in the preceding 12 mo: 1) potential work-related zoonotic disease exposures; 2) protective practices, including use of personal protective equipment (PPE); and 3) barriers and facilitators to PPE use. Summary protective measure scores were calculated and compared with sociodemographic and work-related factors. Surveys were completed by 238 employees from 131 parks in all NPS regions. Seventy-one percent were biologists or technicians, 16% natural resource specialists or managers, and 13% had other job titles. Among a majority of respondents, interactions with animals were infrequent and occurred approximately several times per year as follows: handling live (39%), sick (43%), or dead animals (46%), and drawing blood from animals (42%). The most frequently reported protective measures used were hand hygiene and gloves. Commonly agreed-upon measures that would facilitate PPE use included having PPE stocked and readily available (92%) and having specific PPE kits for use during necropsies (91%) and in remote field settings (91%). Significantly higher summary protective measure scores were found if respondents had either read or reviewed "NPS safe work practices for employees handling wildlife" with their supervisor, had zoonotic disease safety or PPE use included in their employee performance appraisal plans, or had conducted a job-hazard analysis for handling wildlife. Ninety (38%) respondents reported receiving zoonotic disease training. Our findings support the development and implementation of workplace interventions to increase zoonotic disease awareness and promote a culture of

  19. ‘Early Psychosis’ as a Mirror of Biologist Controversies in Post-WarGerman, Anglo-Saxon and Soviet Psychiatry

    Directory of Open Access Journals (Sweden)

    Lara eRzesnitzek

    2013-07-01

    Full Text Available The English term ‘early psychosis’ was coined in the 1930s to refer to feelings of irritability, loss of concentration, hypochondriac ideas, moodiness and lassitude that were seen to precede the onset of clear-cut hallucinations and delusions. The history of thinking about ‘early psychosis’ under names such as ‘latent’, ‘masked’, ‘mild’, ‘simple’ or ‘sluggish’ schizophrenia before World War II and afterwards on the different sides of the Wall and the Iron Curtain reveals ‘early psychosis’ as a mirror of quite aged international biologist controversies that are still alive today and to the same extent as they are misunderstood, are influential in their implications in today’s psychiatry.

  20. Training Experimental Biologists in Bioinformatics

    Directory of Open Access Journals (Sweden)

    Pedro Fernandes

    2012-01-01

    Full Text Available Bioinformatics, for its very nature, is devoted to a set of targets that constantly evolve. Training is probably the best response to the constant need for the acquisition of bioinformatics skills. It is interesting to assess the effects of training in the different sets of researchers that make use of it. While training bench experimentalists in the life sciences, we have observed instances of changes in their attitudes in research that, if well exploited, can have beneficial impacts in the dialogue with professional bioinformaticians and influence the conduction of the research itself.

  1. Teaching experimental design to biologists.

    Science.gov (United States)

    Zolman, J F

    1999-12-01

    The teaching of research design and data analysis to our graduate students has been a persistent problem. A course is described in which students, early in their graduate training, obtain extensive practice in designing experiments and interpreting data. Lecture-discussions on the essentials of biostatistics are given, and then these essentials are repeatedly reviewed by illustrating their applications and misapplications in numerous research design problems. Students critique these designs and prepare similar problems for peer evaluation. In most problems the treatments are confounded by extraneous variables, proper controls may be absent, or data analysis may be incorrect. For each problem, students must decide whether the researchers' conclusions are valid and, if not, must identify a fatal experimental flaw. Students learn that an experiment is a well-conceived plan for data collection, analysis, and interpretation. They enjoy the interactive evaluations of research designs and appreciate the repetitive review of common flaws in different experiments. They also benefit from their practice in scientific writing and in critically evaluating their peers' designs.

  2. Biologists napping while work militarized.

    Science.gov (United States)

    Dando, Malcolm

    2009-08-20

    As researchers discover more agents that alter mental states, the Chemical Weapons Convention needs modification to help ensure that the life sciences are not used for hostile purposes, says Malcolm Dando.

  3. Reproducible Bioinformatics Research for Biologists

    Science.gov (United States)

    This book chapter describes the current Big Data problem in Bioinformatics and the resulting issues with performing reproducible computational research. The core of the chapter provides guidelines and summaries of current tools/techniques that a noncomputational researcher would need to learn to pe...

  4. WImpiBLAST: web interface for mpiBLAST to help biologists perform large-scale annotation using high performance computing.

    Science.gov (United States)

    Sharma, Parichit; Mantri, Shrikant S

    2014-01-01

    The function of a newly sequenced gene can be discovered by determining its sequence homology with known proteins. BLAST is the most extensively used sequence analysis program for sequence similarity search in large databases of sequences. With the advent of next generation sequencing technologies it has now become possible to study genes and their expression at a genome-wide scale through RNA-seq and metagenome sequencing experiments. Functional annotation of all the genes is done by sequence similarity search against multiple protein databases. This annotation task is computationally very intensive and can take days to obtain complete results. The program mpiBLAST, an open-source parallelization of BLAST that achieves superlinear speedup, can be used to accelerate large-scale annotation by using supercomputers and high performance computing (HPC) clusters. Although many parallel bioinformatics applications using the Message Passing Interface (MPI) are available in the public domain, researchers are reluctant to use them due to lack of expertise in the Linux command line and relevant programming experience. With these limitations, it becomes difficult for biologists to use mpiBLAST for accelerating annotation. No web interface is available in the open-source domain for mpiBLAST. We have developed WImpiBLAST, a user-friendly open-source web interface for parallel BLAST searches. It is implemented in Struts 1.3 using a Java backbone and runs atop the open-source Apache Tomcat Server. WImpiBLAST supports script creation and job submission features and also provides a robust job management interface for system administrators. It combines script creation and modification features with job monitoring and management through the Torque resource manager on a Linux-based HPC cluster. Use case information highlights the acceleration of annotation analysis achieved by using WImpiBLAST. Here, we describe the WImpiBLAST web interface features and architecture, explain design

  5. WImpiBLAST: web interface for mpiBLAST to help biologists perform large-scale annotation using high performance computing.

    Directory of Open Access Journals (Sweden)

    Parichit Sharma

    Full Text Available The function of a newly sequenced gene can be discovered by determining its sequence homology with known proteins. BLAST is the most extensively used sequence analysis program for sequence similarity search in large databases of sequences. With the advent of next generation sequencing technologies it has now become possible to study genes and their expression at a genome-wide scale through RNA-seq and metagenome sequencing experiments. Functional annotation of all the genes is done by sequence similarity search against multiple protein databases. This annotation task is computationally very intensive and can take days to obtain complete results. The program mpiBLAST, an open-source parallelization of BLAST that achieves superlinear speedup, can be used to accelerate large-scale annotation by using supercomputers and high performance computing (HPC clusters. Although many parallel bioinformatics applications using the Message Passing Interface (MPI are available in the public domain, researchers are reluctant to use them due to lack of expertise in the Linux command line and relevant programming experience. With these limitations, it becomes difficult for biologists to use mpiBLAST for accelerating annotation. No web interface is available in the open-source domain for mpiBLAST. We have developed WImpiBLAST, a user-friendly open-source web interface for parallel BLAST searches. It is implemented in Struts 1.3 using a Java backbone and runs atop the open-source Apache Tomcat Server. WImpiBLAST supports script creation and job submission features and also provides a robust job management interface for system administrators. It combines script creation and modification features with job monitoring and management through the Torque resource manager on a Linux-based HPC cluster. Use case information highlights the acceleration of annotation analysis achieved by using WImpiBLAST. Here, we describe the WImpiBLAST web interface features and architecture

  6. Modular Affective Reasoning-Based Versatile Introspective Architecture (MARVIN)

    Science.gov (United States)

    2008-08-14

    operating in complex, dynamic, and social environments will require affect-like mechanisms to be effective ( Minsky , 2006; Pfeifer, 1993; Sloman & Croucher...both for eventual transition and short-term, rapid prototyping and evaluation. Task 2: Perform Human Affect and Affective Modeling Literature Review...and development that focuses on designing and developing additional affect-based computational models , rigorously testing and evaluating the

  7. The greatest biologist in 20th century—Francis Crick%20世纪最伟大的生物学家——弗朗西斯?克里克

    Institute of Scientific and Technical Information of China (English)

    顾凡及

    2016-01-01

    A biography of UK scientist Francis Crick who is called as the greatest biologist in 20th century is presented in this article. His contributions to life sciences and his approaches to scholarship are also given.%介绍了被称为"20世纪最伟大的生物学家"的英国科学家克里克的生平、对生命科学的贡献和治学之道.

  8. An Evaluation of the Carbon Sequestration Potential of the Cambro-Ordovician Strata of the Illinois and Michigan Basins. Part 1. Evaluation of Phase 2 CO2 Injection Testing in the Deep Saline Gunter Sandstone Reservoir (Cambro-Ordovician Knox Group), Marvin Blan No. 1 Hancock County, Kentucky Part 2. Time-lapse Three-Dimensional Vertical Seismic Profile (3D-VSP) of Sequestration Target Interval with Injected Fluids

    Energy Technology Data Exchange (ETDEWEB)

    Bowersox, Richard [Univ. of Illinois, Champaign, IL (United States); Hickman, John [Univ. of Illinois, Champaign, IL (United States); Leetaru, Hannes [Univ. of Illinois, Champaign, IL (United States)

    2012-12-20

    Part 1 of this report focuses on results of the western Kentucky carbon storage test, and provides a basis for evaluating injection and storage of supercritical CO2 in Cambro-Ordovician carbonate reservoirs throughout the U.S. Midcontinent. This test demonstrated that the Cambro- Ordovician Knox Group, including the Beekmantown Dolomite, Gunter Sandstone, and Copper Ridge Dolomite in stratigraphic succession from shallowest to deepest, had reservoir properties suitable for supercritical CO2 storage in a deep saline reservoir hosted in carbonate rocks, and that strata with properties sufficient for long-term confinement of supercritical CO2 were present in the deep subsurface. Injection testing with brine and CO2 was completed in two phases. The first phase, a joint project by the Kentucky Geological Survey and the Western Kentucky Carbon Storage Foundation, drilled the Marvin Blan No. 1 carbon storage research well and tested the entire Knox Group section in the open borehole – including the Beekmantown Dolomite, Gunter Sandstone, and Copper Ridge Dolomite – at 1152–2255 m, below casing cemented at 1116 m. During Phase 1 injection testing, most of the 297 tonnes of supercritical CO2 was displaced into porous and permeable sections of the lowermost Beekmantown below 1463 m and Gunter. The wellbore was then temporarily abandoned with a retrievable bridge plug in casing at 1105 m and two downhole pressure-temperature monitoring gauges below the bridge plug pending subsequent testing. Pressure and temperature data were recorded every minute for slightly more than a year, providing a unique record of subsurface reservoir conditions in the Knox. In contrast, Phase 2 testing, this study, tested a mechanically-isolated dolomitic-sandstone interval in the Gunter.

  9. Effects of Pinus flexilis on the dynamics and structure of plant communities on the northern Rocky Mountain front, and, Training biologists for emerging niches in non-traditional jobs

    Science.gov (United States)

    Baumeister, Dayna Marie

    been characterized by invasion of P. flexilis and subsequent shifts in understory species composition apparently facilitated by P. flexilis. Lastly, I examined the role of the emerging science of biomimicry in providing employment for biologists. Biomimicry as a discipline seeks design solutions inspired by nature. Industries employing this tool require biologists with an understanding of biology from a functional perspective, good communication skills, and a background in applied natural history.

  10. Which statistics should tropical biologists learn?

    OpenAIRE

    2010-01-01

    Los biólogos tropicales estudian la biodiversidad más rica y amenazada del planeta, y en estos tiempos de cambio climático y mega-extinción, la necesidad de investigación de buena calidad es más acuciante que en el pasado. Sin embargo, el componente estadístico en la investigación publicada por los autores tropicales adolece a veces de baja calidad en la toma de datos, mal diseño experimental y una visión anticuada del análisis de datos. Para sugerir mejoras en la enseñanza de la estadística,...

  11. Hilda Cid: physicist, crystallographer, structural biologist

    Science.gov (United States)

    Gutiérrez, Gonzalo

    2016-05-01

    A brief review of Dr. Hilda Cid, Chilean scientist who excelled in the field of crystallography, is presented. Dr. Cid was born in 1933 in Talcahuano, where she completed her primary and secondary education, graduating as a Teacher of mathematics and physics from the University of Chile in 1958. She continued graduate studies at MIT, USA, where obtained the PhD in 1964. Upon her return to Chile, she joined the Austral University in Valdivia, where she dedicated to characterize, by X-ray, biological material. During that time, she was actively involved in the social changes taking place in the university and in the country. Thus, following the bloody coup of 1973, she and her family were persecuted and forced to go into exile to Sweden. In the decade of the 1980 she returns to Chile, and settles at University of Concepción, where she teaches, conducts research and organizes a number of latino-american courses and symposiums. Knowing that Hilda Cid formed a real school, where her students -now distinguished professionals and researchers- cast their teachings through Chile and other countries, we ended the article with a reflection about why Hilda Cid, despite its obvious scientific achievements, remains ignored by most of the scientific establishment in Chile.

  12. Intelligent systems for the molecular biologist

    Energy Technology Data Exchange (ETDEWEB)

    Brutlag, D.L.

    1995-12-31

    This tutorial was one of eight tutorials selected to be presented at the Third International Conference on Intelligent Systems for Molecular Biology which was held in the United Kingdom from July 16 to 19, 1995. In this paper, one objective is to identify properties of DNA sequences that determine their function, by computer-aided statistical analysis and to accurately predict its function, given a new sequence. A related problem is to predict protein structure and function from the sequence.

  13. Genetics of asthma: a molecular biologist perspective

    Directory of Open Access Journals (Sweden)

    Ghosh Balaram

    2009-05-01

    Full Text Available Abstract Asthma belongs to the category of classical allergic diseases which generally arise due to IgE mediated hypersensitivity to environmental triggers. Since its prevalence is very high in developed or urbanized societies it is also referred to as "disease of civilizations". Due to its increased prevalence among related individuals, it was understood quite long back that it is a genetic disorder. Well designed epidemiological studies reinforced these views. The advent of modern biological technology saw further refinements in our understanding of genetics of asthma and led to the realization that asthma is not a disorder with simple Mendelian mode of inheritance but a multifactorial disorder of the airways brought about by complex interaction between genetic and environmental factors. Current asthma research has witnessed evidences that are compelling researchers to redefine asthma altogether. Although no consensus exists among workers regarding its definition, it seems obvious that several pathologies, all affecting the airways, have been clubbed into one common category called asthma. Needless to say, genetic studies have led from the front in bringing about these transformations. Genomics, molecular biology, immunology and other interrelated disciplines have unearthed data that has changed the way we think about asthma now. In this review, we center our discussions on genetic basis of asthma; the molecular mechanisms involved in its pathogenesis. Taking cue from the existing data we would briefly ponder over the future directions that should improve our understanding of asthma pathogenesis.

  14. Toward Better Physics Labs for Future Biologists

    CERN Document Server

    Moore, K; Losert, W

    2013-01-01

    We have developed a set of laboratories and hands on activities to accompany a new two-semester interdisciplinary physics course that has been successfully developed and tested in two small test classes of students at the University of Maryland, College Park (UMD) in 2012-2013. We have designed the laboratories to be taken accompanying a reformed course in the student's second year, with calculus, biology, and chemistry as prerequisites. This permits the laboratories to include significant content on physics relevant to cellular scales, from chemical interactions to random motion and charge screening in fluids. We also introduce the students to research-grade equipment and modern physics analysis tools in contexts relevant to biology, while maintaining the pedagogically valuable open-ended laboratory structure of reformed laboratories. Preliminary student results from these two small test classes are discussed.

  15. 78 FR 24447 - Goldman Sachs Trust, et al.; Notice of Application

    Science.gov (United States)

    2013-04-25

    ... Sachs, an investment adviser registered under the Advisers Act and a broker-dealer registered under the..., to the extent consistent with its investment objectives, policies, strategies and limitations, in..., or broker or dealer if registered under the Securities Exchange Act of 1934 (``Exchange Act''),...

  16. A view of evolution by a Christian biologist

    Directory of Open Access Journals (Sweden)

    Elizabeth Jordaan

    1984-03-01

    Full Text Available This paper, which originated as an address to a gathering of Dutch Reformed Ministers in Potchefstroom, deals with the response of a Christian to concepts of evolution. The paper looks at the concept of “the beginning”, the origin of life , genetics, mutation and natural selection, the origin of diversity or speciation, man as a biological species, the missing link (in which attention is given to various theories, and finally theories of human evolution. These include the neoteny theory, the savannah theory and the aquatic theory. Following a discussion of the various aspects of these theories, the authors go on to a discussion of the evolution of intelligence and culture, and reach the conclusion that “for a Christian, evolution may help him to understand more about God and his love and his work, and also then to have more security in the belief in God”.

  17. NEXUS/Physics: An interdisciplinary repurposing of physics for biologists

    CERN Document Server

    Redish, E F; Carleton, K L; Cooke, T J; Cooper, M; Crouch, C H; Dreyfus, B W; Geller, B; Giannini, J; Gouvea, J Svoboda; Klymkowsky, M W; Losert, W; Moore, K; Presson, J; Sawtelle, V; Thompson, K V; Turpen, C

    2013-01-01

    In response to increasing calls for the reform of the curriculum for life science majors and pre-medical students (Bio2010, Scientific Foundations for Future Physicians, Vision & Change), an interdisciplinary team has created NEXUS/Physics: a reinvention of an introductory physics curriculum for the life sciences. The curriculum interacts strongly and supportively with introductory biology and chemistry cours-es taken by life sciences students, with the goal of helping students build general, multi-discipline scientific competencies. In order to do this, our two-semester NEXUS/Physics course sequence is positioned as a second year course so students will have had some exposure to basic concepts in biology and chemistry. NEXUS/Physics stresses interdisciplinary examples and the content differs markedly from traditional introductory physics to facilitate this, including extending the discussion of energy to include interatomic potentials and chemical reactions, extending the discussion of thermodynamics to ...

  18. Thousands of rab GTPases for the cell biologist.

    Directory of Open Access Journals (Sweden)

    Yoan Diekmann

    2011-10-01

    Full Text Available Rab proteins are small GTPases that act as essential regulators of vesicular trafficking. 44 subfamilies are known in humans, performing specific sets of functions at distinct subcellular localisations and tissues. Rab function is conserved even amongst distant orthologs. Hence, the annotation of Rabs yields functional predictions about the cell biology of trafficking. So far, annotating Rabs has been a laborious manual task not feasible for current and future genomic output of deep sequencing technologies. We developed, validated and benchmarked the Rabifier, an automated bioinformatic pipeline for the identification and classification of Rabs, which achieves up to 90% classification accuracy. We cataloged roughly 8.000 Rabs from 247 genomes covering the entire eukaryotic tree. The full Rab database and a web tool implementing the pipeline are publicly available at www.RabDB.org. For the first time, we describe and analyse the evolution of Rabs in a dataset covering the whole eukaryotic phylogeny. We found a highly dynamic family undergoing frequent taxon-specific expansions and losses. We dated the origin of human subfamilies using phylogenetic profiling, which enlarged the Rab repertoire of the Last Eukaryotic Common Ancestor with Rab14, 32 and RabL4. Furthermore, a detailed analysis of the Choanoflagellate Monosiga brevicollis Rab family pinpointed the changes that accompanied the emergence of Metazoan multicellularity, mainly an important expansion and specialisation of the secretory pathway. Lastly, we experimentally establish tissue specificity in expression of mouse Rabs and show that neo-functionalisation best explains the emergence of new human Rab subfamilies. With the Rabifier and RabDB, we provide tools that easily allows non-bioinformaticians to integrate thousands of Rabs in their analyses. RabDB is designed to enable the cell biology community to keep pace with the increasing number of fully-sequenced genomes and change the scale at which we perform comparative analysis in cell biology.

  19. The riddle of ``life,'' a biologist's critical view

    Science.gov (United States)

    Penzlin, Heinz

    2009-01-01

    To approach the question of what life is, we first have to state that life exists exclusively as the “being-alive” of discrete spatio-temporal entities. The simplest “unit” that can legitimately be considered to be alive is an intact prokaryotic cell as a whole. In this review, I discuss critically various aspects of the nature and singularity of living beings from the biologist’s point of view. In spite of the enormous richness of forms and performances in the biotic realm, there is a considerable uniformity in the chemical “machinery of life,” which powers all organisms. Life represents a dynamic state; it is performance of a system of singular kind: “life-as-action” approach. All “life-as-things” hypotheses are wrong from the beginning. Life is conditioned by certain substances but not defined by them. Living systems are endowed with a power to maintain their inherent functional order (organization) permanently against disruptive influences. The term organization inherently involves the aspect of functionality, the teleonomic, purposeful cooperation of structural and functional elements. Structures in turn require information for their specification, and information presupposes a source. This source is constituted in living systems by the nucleic acids. Organisms are unique in having a capacity to use, maintain, and replicate internal information, which yields the basis for their specific organization in its perpetuation. The existence of a genome is a necessary condition for life and one of the absolute differences between living and non-living matter. Organization includes both what makes life possible and what is determined by it. It is not something “implanted” into the living beings but has its origin and capacity for maintenance within the system itself. It is the essence of life. The property of being alive we can consider as an emergent property of cells that corresponds to a certain level of self-maintained complex order or organization.

  20. Thousands of rab GTPases for the cell biologist.

    Science.gov (United States)

    Diekmann, Yoan; Seixas, Elsa; Gouw, Marc; Tavares-Cadete, Filipe; Seabra, Miguel C; Pereira-Leal, José B

    2011-10-01

    Rab proteins are small GTPases that act as essential regulators of vesicular trafficking. 44 subfamilies are known in humans, performing specific sets of functions at distinct subcellular localisations and tissues. Rab function is conserved even amongst distant orthologs. Hence, the annotation of Rabs yields functional predictions about the cell biology of trafficking. So far, annotating Rabs has been a laborious manual task not feasible for current and future genomic output of deep sequencing technologies. We developed, validated and benchmarked the Rabifier, an automated bioinformatic pipeline for the identification and classification of Rabs, which achieves up to 90% classification accuracy. We cataloged roughly 8.000 Rabs from 247 genomes covering the entire eukaryotic tree. The full Rab database and a web tool implementing the pipeline are publicly available at www.RabDB.org. For the first time, we describe and analyse the evolution of Rabs in a dataset covering the whole eukaryotic phylogeny. We found a highly dynamic family undergoing frequent taxon-specific expansions and losses. We dated the origin of human subfamilies using phylogenetic profiling, which enlarged the Rab repertoire of the Last Eukaryotic Common Ancestor with Rab14, 32 and RabL4. Furthermore, a detailed analysis of the Choanoflagellate Monosiga brevicollis Rab family pinpointed the changes that accompanied the emergence of Metazoan multicellularity, mainly an important expansion and specialisation of the secretory pathway. Lastly, we experimentally establish tissue specificity in expression of mouse Rabs and show that neo-functionalisation best explains the emergence of new human Rab subfamilies. With the Rabifier and RabDB, we provide tools that easily allows non-bioinformaticians to integrate thousands of Rabs in their analyses. RabDB is designed to enable the cell biology community to keep pace with the increasing number of fully-sequenced genomes and change the scale at which we perform comparative analysis in cell biology.

  1. Beyond Borders: Zoo as Training Location for Wildlife Biologists

    Science.gov (United States)

    Melber, Leah M.; Bergren, Rachel; Santymire, Rachel

    2011-01-01

    The role of institutions such as zoos in global conservation efforts is critical. In addition to serving as informal learning centers for the general public, these institutions are well-positioned to provide training and professional development for the next generation of conservation scientists. And while many organizations traditionally have…

  2. Putting computational modeling at the fingertips of bench biologists

    DEFF Research Database (Denmark)

    Sonnenschein, Nikolaus; Herrgard, Markus

    Communication is key in successful collaborations between theoretical and experimental life scientists. In our line of work we integrate physiological and systems-level data of cell factories with constraint-based Modeling approaches to predict suitable targets for metabolic engineering. The most...

  3. An introduction to scripting in Ruby for biologists

    Directory of Open Access Journals (Sweden)

    Law Andy

    2009-07-01

    Full Text Available Abstract The Ruby programming language has a lot to offer to any scientist with electronic data to process. Not only is the initial learning curve very shallow, but its reflection and meta-programming capabilities allow for the rapid creation of relatively complex applications while still keeping the code short and readable. This paper provides a gentle introduction to this scripting language for researchers without formal informatics training such as many wet-lab scientists. We hope this will provide such researchers an idea of how powerful a tool Ruby can be for their data management tasks and encourage them to learn more about it.

  4. What every conservation biologist should know about economic theory.

    Science.gov (United States)

    Gowdy, John; Hall, Charles; Klitgaard, Kent; Krall, Lisi

    2010-12-01

    The last century has seen the ascendance of a core economic model, which we will refer to as Walrasian economics. This model is driven by the psychological assumptions that humans act only in a self-referential and narrowly rational way and that production can be described as a self-contained circular flow between firms and households. These assumptions have critical implications for the way economics is used to inform conservation biology. Yet the Walrasian model is inconsistent with a large body of empirical evidence about actual human behavior, and it violates a number of basic physical laws. Research in behavioral science and neuroscience shows that humans are uniquely social animals and not self-centered rational economic beings. Economic production is subject to physical laws including the laws of thermodynamics and mass balance. In addition, some contemporary economic theory, spurred by exciting new research in human behavior and a wealth of data about the negative global impact of the human economy on natural systems, is moving toward a world view that places consumption and production squarely in its behavioral and biophysical context. We argue that abandoning the straightjacket of the Walrasian core is essential to further progress in understanding the complex, coupled interactions between the human economy and the natural world. We call for a new framework for economic theory and policy that is consistent with observed human behavior, recognizes the complex and frequently irreversible interaction between human and natural systems, and directly confronts the cumulative negative effects of the human economy on the Earth's life support systems. Biophysical economics and ecological economics are two emerging economic frameworks in this movement.

  5. Molecular Biologists:James Watson and Francis Crick

    Institute of Scientific and Technical Information of China (English)

    李琳

    2006-01-01

    On Feb. 28, 1953, Francis Crick walked into the Eagle pub in Cambridge, England, and, as James Watson later recalled, announced that "we had found the secret of life. " Actually, they had. That morning, Watson and Crick had figured out the structure of deoxyribonucleic acid, DNA. And that structure-a "double helix" that can "unzip" to make copies of itself-confirmed suspicions that DNA carries life ’ s hereditary information.

  6. Toward mobile 3D visualization for structural biologists.

    Science.gov (United States)

    Tanramluk, Duangrudee; Akavipat, Ruj; Charoensawan, Varodom

    2013-12-01

    Technological advances in crystallography have led to the ever-rapidly increasing number of biomolecular structures deposited in public repertoires. This undoubtedly shifts the bottleneck of structural biology research from obtaining high-quality structures to data analysis and interpretation. The recently available glasses-free autostereoscopic laptop offers an unprecedented opportunity to visualize and study 3D structures using a much more affordable, and for the first time, portable device. Together with a gamepad re-programmed for 3D structure controlling, we describe how the gaming technologies can deliver the output 3D images for high-quality viewing, comparable to that of a passive stereoscopic system, and can give the user more control and flexibility than the conventional controlling setup using only a mouse and a keyboard.

  7. Engineering central metabolism - a grand challenge for plant biologists.

    Science.gov (United States)

    Sweetlove, Lee J; Nielsen, Jens; Fernie, Alisdair R

    2016-12-22

    The goal of increasing crop productivity and nutrient-use efficiency is being addressed by a number of ambitious research projects seeking to re-engineer photosynthetic biochemistry. Many of these projects will require the engineering of substantial changes in fluxes of central metabolism. However, as has been amply demonstrated in simpler systems such as microbes, central metabolism is extremely difficult to rationally engineer. This is because of multiple layers of regulation that operate to maintain metabolic steady state and because of the highly connected nature of central metabolism. In this review we discuss new approaches for metabolic engineering that have the potential to address these problems and dramatically improve the success with which we can rationally engineer central metabolism in plants. In particular, we advocate the adoption of an iterative 'design-build-test-learn' cycle using fast-to-transform model plants as test beds. This approach can be realised by coupling new molecular tools to incorporate multiple transgenes in nuclear and plastid genomes with computational modelling to design the engineering strategy and to understand the metabolic phenotype of the engineered organism. We also envisage that mutagenesis could be used to fine-tune the balance between the endogenous metabolic network and the introduced enzymes. Finally, we emphasise the importance of considering the plant as a whole system and not isolated organs: the greatest increase in crop productivity will be achieved if both source and sink metabolism are engineered.

  8. Biologists behaving badly: vitalism and the language of language.

    Science.gov (United States)

    Oyama, Susan

    2010-01-01

    A comparison is made between Biologos, the "language of language" that predominates in current infocentric biology, and Logos, the classic bringer of form to chaos. The immaterial information on which Biologos is based is seen to bear intriguing similarities to just the sort of disembodied formative powers that an aggressively materialist biology has long derided. I address these issues by meeting a (perhaps only hypothetical) charge that my own work is in some sense vitalist, first with the usual flat denial, then with a countercharge. My third move is a nontraditional one, meant not as capitulation or acquiescence, but as an acknowledgement that the terms of this debate, never clear, continue to be remarkably ill-defined. The question of how best to think about development, or epigenesis--the process whereby organisms come into being--remains a legitimately contested and difficult one.

  9. The Art of Political Murder de Francisco Goldman y el policial de no-ficción entre Estados Unidos y Guatemala

    Directory of Open Access Journals (Sweden)

    Andrea Pezzé

    2016-05-01

    Full Text Available This essay analyses the use of crime fiction in Francisco Goldman’s reportage The Art of Political Murder, and the contribution this makes to political change in the recent history of Guatemala. The aim of Goldman’s investigative report was not just to find a murderer, but above all to criticize the abuses of power perpetrated with impunity by the ‘State’, and the practices put in place to eradicate dissidence. To understand how the features of detective fiction are used in journalism to support the search for truth, the essay examines the social power of different typologies of Crime Novel. Goldman’s The Art of Political Murder is read from the viewpoint of literary Testimonio, against the Guatemalan and Central-American literary background, to see how it can contribute to the current struggle for identity.

  10. Repliek comments on "a view of evolution by a Christian biologist' 1

    Directory of Open Access Journals (Sweden)

    J. D. Kies

    1986-03-01

    Full Text Available Die Ou en Nuwe Testamente van die Bybel vorm 'n eenheid, en Christene wat uit laasgenoemde lewe, moet die uitsprake van die N T oor die OT aanvaar. Christus se eie woorde was dat man en vrou in die begin geskape is. Dit laat geen ruimte vir 'n lang evolusionére geskiedenis nie. Bowendien het Jesus gesé dat as mens nie glo wat Moses geskryf het nie, jy ook nie Sy woorde kan glo nie (Joh. 5:46,47.

  11. Modeling for (physical) biologists: an introduction to the rule-based approach.

    Science.gov (United States)

    Chylek, Lily A; Harris, Leonard A; Faeder, James R; Hlavacek, William S

    2015-07-16

    Models that capture the chemical kinetics of cellular regulatory networks can be specified in terms of rules for biomolecular interactions. A rule defines a generalized reaction, meaning a reaction that permits multiple reactants, each capable of participating in a characteristic transformation and each possessing certain, specified properties, which may be local, such as the state of a particular site or domain of a protein. In other words, a rule defines a transformation and the properties that reactants must possess to participate in the transformation. A rule also provides a rate law. A rule-based approach to modeling enables consideration of mechanistic details at the level of functional sites of biomolecules and provides a facile and visual means for constructing computational models, which can be analyzed to study how system-level behaviors emerge from component interactions.

  12. Who Wants to Be a Biologist? An Excellent Quiz Tool for Students

    Science.gov (United States)

    Turner, Ian J.

    2008-01-01

    Lectures tend to be a largely passive experience with respect to student learning and it has been shown that engaging students in their own learning can increase their understanding. Quizzes have been shown to be a mechanism that improves the student learning experience, and other key factors such as a competitive environment, enjoyment, and a…

  13. In memoriam Prof. Dr J.T. Wiebes (1931-1999), evolutionary biologist and systematic entomologist

    NARCIS (Netherlands)

    Bruggen, van A.C.; Achterberg, van C.

    2000-01-01

    Born on 13 September 1931 in Rotterdam, Jacobus Theodorus [Koos] Wiebes read biology at Leiden University where he obtained his Ph.D. in 1963 on studies of Indo-Australian fig wasps. He started working on spiders (Lycosidae, Pisauridae) and beetles (Carabidae, Cetoniidae, Helodidae), but he earned h

  14. Modeling for (physical) biologists: an introduction to the rule-based approach

    Science.gov (United States)

    Chylek, Lily A.; Harris, Leonard A.; Faeder, James R.; Hlavacek, William S.

    2015-07-01

    Models that capture the chemical kinetics of cellular regulatory networks can be specified in terms of rules for biomolecular interactions. A rule defines a generalized reaction, meaning a reaction that permits multiple reactants, each capable of participating in a characteristic transformation and each possessing certain, specified properties, which may be local, such as the state of a particular site or domain of a protein. In other words, a rule defines a transformation and the properties that reactants must possess to participate in the transformation. A rule also provides a rate law. A rule-based approach to modeling enables consideration of mechanistic details at the level of functional sites of biomolecules and provides a facile and visual means for constructing computational models, which can be analyzed to study how system-level behaviors emerge from component interactions.

  15. Databases for marine biologists and biotechnologists: The state-of-the art and prospects

    Digital Repository Service at National Institute of Oceanography (India)

    Chavan, V.S.

    stream_size 6 stream_content_type text/plain stream_name Online_CDROM_Rev_17_77.pdf.txt stream_source_info Online_CDROM_Rev_17_77.pdf.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset=ISO-8859-1 ...

  16. Super-resolution imaging strategies for cell biologists using a spinning disk microscope.

    Science.gov (United States)

    Hosny, Neveen A; Song, Mingying; Connelly, John T; Ameer-Beg, Simon; Knight, Martin M; Wheeler, Ann P

    2013-01-01

    In this study we use a spinning disk confocal microscope (SD) to generate super-resolution images of multiple cellular features from any plane in the cell. We obtain super-resolution images by using stochastic intensity fluctuations of biological probes, combining Photoactivation Light-Microscopy (PALM)/Stochastic Optical Reconstruction Microscopy (STORM) methodologies. We compared different image analysis algorithms for processing super-resolution data to identify the most suitable for analysis of particular cell structures. SOFI was chosen for X and Y and was able to achieve a resolution of ca. 80 nm; however higher resolution was possible >30 nm, dependant on the super-resolution image analysis algorithm used. Our method uses low laser power and fluorescent probes which are available either commercially or through the scientific community, and therefore it is gentle enough for biological imaging. Through comparative studies with structured illumination microscopy (SIM) and widefield epifluorescence imaging we identified that our methodology was advantageous for imaging cellular structures which are not immediately at the cell-substrate interface, which include the nuclear architecture and mitochondria. We have shown that it was possible to obtain two coloured images, which highlights the potential this technique has for high-content screening, imaging of multiple epitopes and live cell imaging.

  17. Super-resolution imaging strategies for cell biologists using a spinning disk microscope.

    Directory of Open Access Journals (Sweden)

    Neveen A Hosny

    Full Text Available In this study we use a spinning disk confocal microscope (SD to generate super-resolution images of multiple cellular features from any plane in the cell. We obtain super-resolution images by using stochastic intensity fluctuations of biological probes, combining Photoactivation Light-Microscopy (PALM/Stochastic Optical Reconstruction Microscopy (STORM methodologies. We compared different image analysis algorithms for processing super-resolution data to identify the most suitable for analysis of particular cell structures. SOFI was chosen for X and Y and was able to achieve a resolution of ca. 80 nm; however higher resolution was possible >30 nm, dependant on the super-resolution image analysis algorithm used. Our method uses low laser power and fluorescent probes which are available either commercially or through the scientific community, and therefore it is gentle enough for biological imaging. Through comparative studies with structured illumination microscopy (SIM and widefield epifluorescence imaging we identified that our methodology was advantageous for imaging cellular structures which are not immediately at the cell-substrate interface, which include the nuclear architecture and mitochondria. We have shown that it was possible to obtain two coloured images, which highlights the potential this technique has for high-content screening, imaging of multiple epitopes and live cell imaging.

  18. Making sense of biologists' teaching: Two case studies of beliefs and discourse practices

    Science.gov (United States)

    Fifield, Steven James

    1999-09-01

    Undergraduate science courses are often criticized for their overemphasis of content coverage, neglect of inquiry approaches, and misrepresentation of the nature of science. Because conventional courses are influential models for future science teachers, they are often viewed as impediments to K--12 science education reform. To effectively modify how professors teach, we first need to better understand their beliefs and practices as teachers. This is an interpretive study of how two biology professors (Jim and Sue) make sense of their classroom practices in an introductory undergraduate course. Interviews are used to analyze their beliefs about teaching, learning, and science. Discourse analysis of lectures on classical genetics is used to examine their classroom practices as situated constructions of scientific knowledge. The two professors' held distinct beliefs about teaching and learning that were intricately interwoven with their beliefs about science. Jim's beliefs were largely consistent with conventional approaches to introductory science courses. He thought that introductory courses support the development of knowledge and skills that students need before they can engage in scientific inquiry. Sarah was critical of these conventional approaches. She valued courses that foster active learning and focus on applications of biology that are relevant to students' lives. But she could not enact many of her beliefs due to situational constraints associated with the course. Instead she viewed her efforts to help students succeed in a conventional course as a way to resist her colleagues' expectations that most students cannot do well in science. Discourse analysis of the professors' lectures revealed that they both relied on narratives to represent concepts in classical genetics. These narratives of concepts were distinct from other narrative forms in technical and popular presentations of biology. The relationship among these professors' beliefs and classroom practices suggest that what scientists' believe and do as teachers should be understood as dimensions of the nature of science. From this perspective, for some science professors, science education reform may entail not simply using different instructional strategies, but doing and thinking about science in radically new ways. The implications of this perspective for educational reform are discussed.

  19. The biologist's apprentices: A role for undergraduate research in premedical science education

    Science.gov (United States)

    Kudish, Philip

    This manuscript represents a project in two parts. Part one describes the perceptions of physicians, scientists and undergraduate researchers concerning if/why participation in undergraduate research is preparative for aspiring physicians. These communities in large part perceive that scientific habits appropriated through participation in professional research laboratories orient premedical students to medical classroom and clinical practices. Reasons for these perceptions are described. Topics of discussion include how these perceptions support descriptions of the nature of identities in communities of practice by situated cognition theorists. Part two describes the University-based undergraduate research experiences of four premedical students as they appropriate these selfsame habits. Themes in habit appropriation through these experiences are described in each case and across case studies. Patterns in habit appropriation which support the cognitive apprenticeship model of learning are also discussed. Situations comprising these experiences are described and discussed in terms of the convergence of these students' concurrent and desired future identities with their lived experiences as legitimate peripheral participants in the scientific community of practice. Formal and informal structures in the scientific community at the disciplinary, institutional and local levels were found to regulate the means and outcomes of scientific habit formation. Interplay between nascent scientific identities, established identities and desired physician identities were found to be of particular import to scientific enculturation through undergraduate research.

  20. When biologists and engineers collide: Habitat conservation planning in the middle of urbanized development

    Science.gov (United States)

    McKinney, Larry D.; Murphy, Robert

    1996-11-01

    The City of Austin, Texas, is one of the fastest growing metropolitan areas in the United States. It is also in one of the most biologically diverse terrestrial ecosystems in the world: the Balcones Canyonlands. Five cave invertebrates and two species of birds that inhabit the area are listed as threatened or endangered, two species of plants are candidates for listing, several others are considered rare and of concern, and a species of the salamander has also been proposed for listing. A habitat conservation plan, of “national significance⋯” according to Secretary of Interior Bruce Babbit (Haurwitz 1996), has been under development for the last several years to conserve those endangered species through a 2400-ha system of preserves and to allow development to continue in more than 162,000 ha of surrounding area. The preserve system, comprising several units ranging in size from less than a hundred to several thousand hectares, would be bordered in many instances by developed areas. Development and maintenance of the infrastructure necessary for new and existing development, both commercial and residential, could have negated the biological value of the preserves (e.g., power-line corridors, water-treatment pipelines and facilities). The challenge of bringing this plan to fruition illustrates the complex biological, technical, and sociological context within which habitat conservation planning may occur. Resolving resource use conflicts of this nature have several commonalities that overarch these contexts. If recognized and addressed, one may move easily and foster positive results. These commonalities can be expressed as principles such as: relying on scientists to recognize, but not solve problems; acting before a scientific consensus is achieved; including human motivation and responses as part of the system to be studied and managed; and confronting uncertainty.

  1. Une expérience scientifique et didactique : enseigner l’informatique aux biologistes

    OpenAIRE

    2014-01-01

    Tout a commencé avec James D. Watson, Francis Crick, Rosalind Elsie Franklin et quelques autres dans les années 1950. Ils nous ont appris que la conformation des êtres vivants se déduisait de l’information génétique codée par l’acide désoxyribonucléique (ADN) de leurs cellules. Les macromolécules (on dit aussi polymères) d’ADN sont de longues chaînes de motifs moléculaires élémentaires, les nucléotides, dont il existe quatre variétés : l’adénine (notée A), la thymine (notée T), la cytosine (n...

  2. In memorium Dr. Agatha Gijzen (1904-1995), eminent museum historian and zoo biologist

    NARCIS (Netherlands)

    Bruggen, van A.C.

    1996-01-01

    Dr Agatha Gijzen (Rotterdam *9 October 1904, Merksem/Belgium †19 February 1995) was a remarkable zoologist in more than one respect. Although her professional career, spanning more than three and a half decades, was largely spent as a staff zoologist in the service of the famous Antwerp/ Planckendae

  3. Extraction of High Quality RNA from Cannabis sativa Bast Fibres: A Vademecum for Molecular Biologists

    Directory of Open Access Journals (Sweden)

    Gea Guerriero

    2016-07-01

    Full Text Available In plants there is no universal protocol for RNA extraction, since optimizations are required depending on the species, tissues and developmental stages. Some plants/tissues are rich in secondary metabolites or synthesize thick cell walls, which hinder an efficient RNA extraction. One such example is bast fibres, long extraxylary cells characterized by a thick cellulosic cell wall. Given the economic importance of bast fibres, which are used in the textile sector, as well as in biocomposites as green substitutes of glass fibres, it is desirable to better understand their development from a molecular point of view. This knowledge favours the development of biotechnological strategies aimed at improving specific properties of bast fibres. To be able to perform high-throughput analyses, such as, for instance, transcriptomics of bast fibres, RNA extraction is a crucial and limiting step. We here detail a protocol enabling the rapid extraction of high quality RNA from the bast fibres of textile hemp, Cannabis sativa L., a multi-purpose fibre crop standing in the spotlight of research.

  4. [G. W. Leibniz: medicine and the sciences of life: 2nd part: Leibniz as a "biologist"].

    Science.gov (United States)

    Chazaud, J

    1996-01-01

    Many features of Leibniz's philosophy are a ... "naturalization" of the finding of contemporary scientists. For instance "the Monad", the fondamental element of his system, derives from Glisson's conceptions and Leeuwenhoek's observations. Among others, his ideas on generation stem from a mediation on the Dutchman's and Swammerdam's and Malpighi's works. Through them, he became a partner in the ovulists' quarrel and in the discussion about formal specification. Most of all, he expressed an amazing transformist and paleontological intuition, sensibilizing himself to comparative anatomy and to fossil imprints study. Generation and creative evolution of beings and species were logically accompanied by a reflection on death as being part of the life processes.

  5. Game on, science - how video game technology may help biologists tackle visualization challenges.

    Directory of Open Access Journals (Sweden)

    Zhihan Lv

    Full Text Available The video games industry develops ever more advanced technologies to improve rendering, image quality, ergonomics and user experience of their creations providing very simple to use tools to design new games. In the molecular sciences, only a small number of experts with specialized know-how are able to design interactive visualization applications, typically static computer programs that cannot easily be modified. Are there lessons to be learned from video games? Could their technology help us explore new molecular graphics ideas and render graphics developments accessible to non-specialists? This approach points to an extension of open computer programs, not only providing access to the source code, but also delivering an easily modifiable and extensible scientific research tool. In this work, we will explore these questions using the Unity3D game engine to develop and prototype a biological network and molecular visualization application for subsequent use in research or education. We have compared several routines to represent spheres and links between them, using either built-in Unity3D features or our own implementation. These developments resulted in a stand-alone viewer capable of displaying molecular structures, surfaces, animated electrostatic field lines and biological networks with powerful, artistic and illustrative rendering methods. We consider this work as a proof of principle demonstrating that the functionalities of classical viewers and more advanced novel features could be implemented in substantially less time and with less development effort. Our prototype is easily modifiable and extensible and may serve others as starting point and platform for their developments. A webserver example, standalone versions for MacOS X, Linux and Windows, source code, screen shots, videos and documentation are available at the address: http://unitymol.sourceforge.net/.

  6. Marine Mammal Necropsy: An Introductory Guide for Stranding Responders and Field Biologists

    Science.gov (United States)

    2007-09-01

    lung, liver, spleen, lymph nodes and brain. Additional samples may include skin, mucocutaneous junctions or the oral cavity, rectum, and urogenital tract... urogenital tracts. Consult the working researcher or lab in advance for re- quired tissues. A small amount of tissue is needed and can be collected in...the gastro-intestinal system do not contaminate other tissues. 38 Tracheobronchial ( TB ) Lymph Node: The TB lymph node is located proximal to the

  7. Introductory science and mathematics education for 21st-Century biologists.

    Science.gov (United States)

    Bialek, William; Botstein, David

    2004-02-06

    Galileo wrote that "the book of nature is written in the language of mathematics"; his quantitative approach to understanding the natural world arguably marks the beginning of modern science. Nearly 400 years later, the fragmented teaching of science in our universities still leaves biology outside the quantitative and mathematical culture that has come to define the physical sciences and engineering. This strikes us as particularly inopportune at a time when opportunities for quantitative thinking about biological systems are exploding. We propose that a way out of this dilemma is a unified introductory science curriculum that fully incorporates mathematics and quantitative thinking.

  8. POLICY ADVOCACY IN SCIENCE: PREVALENCE, PERSPECTIVES, AND IMPLICATIONS FOR CONSERVATION BIOLOGISTS

    Science.gov (United States)

    Much debate and discussion has focused on the relationship between science and advocacy, and the role of scientists in influencing public policy. Some argue that advocacy is widespread within scientific literature, however, data to evaluate that contention are lacking. We examine...

  9. Synthetic biologists spring into action at the 245th American Chemical Society National Meeting.

    Science.gov (United States)

    Glasgow, Jeff E; Tullman-Ercek, Danielle

    2013-06-21

    As the field of synthetic biology continues to define itself, it has merged concepts from many related areas of research: molecular biology, genetics, bioengineering, and chemistry. At the 2013 Spring American Chemical Society National Meeting in New Orleans, LA, this mixture was manifested in a wealth of sessions emphasizing the use of modern synthetic biological approaches to solve many of today's biggest chemical problems. As a result of the field's diverse yet pervasive nature, synthetic biology concepts were present in several of the conferences many divisions, including Biological Chemistry, Biochemical Technology, Cellulose and Renewable Materials, and several others. Here we offer a snapshot of some of the exciting research discussed in the dedicated synthetic biology sessions throughout the week.

  10. Systems Biology of Cancer: A Challenging Expedition for Clinical and Quantitative Biologists

    Directory of Open Access Journals (Sweden)

    Ilya eKorsunsky

    2014-08-01

    Full Text Available A systems-biology approach to complex disease (such as cancer is now complementing traditional experience-based approaches, which have typically been invasive and expensive. The rapid progress in biomedical knowledge is enabling the targeting of disease with therapies that are precise, proactive, preventive and personalized. In this paper, we summarize and classify models of systems biology and model-checking tools which have been used to great success in computational biology and related fields. We demonstrate how these models and tools have been used to study some of the twelve biochemical pathways implicated in but not unique to pancreatic cancer, and conclude that the resulting mechanistic models will need to be further enhanced by various abstraction techniques to interpret phenomenological models of cancer progression.

  11. Systems biology of cancer: a challenging expedition for clinical and quantitative biologists.

    Science.gov (United States)

    Korsunsky, Ilya; McGovern, Kathleen; LaGatta, Tom; Olde Loohuis, Loes; Grosso-Applewhite, Terri; Griffeth, Nancy; Mishra, Bud

    2014-01-01

    A systems-biology approach to complex disease (such as cancer) is now complementing traditional experience-based approaches, which have typically been invasive and expensive. The rapid progress in biomedical knowledge is enabling the targeting of disease with therapies that are precise, proactive, preventive, and personalized. In this paper, we summarize and classify models of systems biology and model checking tools, which have been used to great success in computational biology and related fields. We demonstrate how these models and tools have been used to study some of the twelve biochemical pathways implicated in but not unique to pancreatic cancer, and conclude that the resulting mechanistic models will need to be further enhanced by various abstraction techniques to interpret phenomenological models of cancer progression.

  12. Game on, science - how video game technology may help biologists tackle visualization challenges.

    Science.gov (United States)

    Lv, Zhihan; Tek, Alex; Da Silva, Franck; Empereur-mot, Charly; Chavent, Matthieu; Baaden, Marc

    2013-01-01

    The video games industry develops ever more advanced technologies to improve rendering, image quality, ergonomics and user experience of their creations providing very simple to use tools to design new games. In the molecular sciences, only a small number of experts with specialized know-how are able to design interactive visualization applications, typically static computer programs that cannot easily be modified. Are there lessons to be learned from video games? Could their technology help us explore new molecular graphics ideas and render graphics developments accessible to non-specialists? This approach points to an extension of open computer programs, not only providing access to the source code, but also delivering an easily modifiable and extensible scientific research tool. In this work, we will explore these questions using the Unity3D game engine to develop and prototype a biological network and molecular visualization application for subsequent use in research or education. We have compared several routines to represent spheres and links between them, using either built-in Unity3D features or our own implementation. These developments resulted in a stand-alone viewer capable of displaying molecular structures, surfaces, animated electrostatic field lines and biological networks with powerful, artistic and illustrative rendering methods. We consider this work as a proof of principle demonstrating that the functionalities of classical viewers and more advanced novel features could be implemented in substantially less time and with less development effort. Our prototype is easily modifiable and extensible and may serve others as starting point and platform for their developments. A webserver example, standalone versions for MacOS X, Linux and Windows, source code, screen shots, videos and documentation are available at the address: http://unitymol.sourceforge.net/.

  13. CAS Biologists in Shanghai Step up Cooperation with Their West European Peers

    Institute of Scientific and Technical Information of China (English)

    Zhang Qin

    2003-01-01

    @@ Ⅰ. International Cooperation: A Booster for Developing Highlevel Research Bodies The Shanghai Institutes for Biological Sciences (SIBS), a CAS research arm in biology, consists of the Institute Biochemistry and Cell Biology, the Institute of Neuroscience, the Institute of Materia Medica, the Institute of Physiology and Ecology, and the Institute for Nutritional Sciences. In response to the current trends of S&T globalization and the interdisciplinary development of the life sciences, it deems international cooperation amajor component of its effort to uplift the overall capacity of knowledge creation at SIBS.

  14. Out Flying the Eagle: China’s Drive for Domestic Economic Innovation and Its Impact on U.S.-China Relations

    Science.gov (United States)

    2014-03-01

    2006). Source: Goldman Sachs. BRICs and Beyond. Goldman Sachs Global Economics Group, 2007.145 The Chinese Communist Party, in order to maintain...September 2010). 145 Goldman Sachs, BRICs and Beyond, Goldman Sachs Global Economics Group, (2007). 76 States despite increasing interdependence...muenchen.de/30012/. Goldman Sachs. BRICs and Beyond. New York: Goldman Sachs Global Economics Group, 2007. Huang, Can , Celeste Amorim, Mark

  15. Substance use

    Science.gov (United States)

    Substance abuse; Illicit drug abuse; Narcotic abuse; Hallucinogen abuse ... Arlington, VA: American Psychiatric Publishing. 2013. Weiss RD. Drugs of abuse. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  16. [Computation of the K+, Na+ and Cl- fluxes through plasma membrane of animal cell with Na+/K+ pump, NKCC, NC cotransporters, and ionic channels with and without non-Goldman rectification in K+ channels. Norma and apoptosis].

    Science.gov (United States)

    Rubashkin, A A; Iurinskaia, V E; Vereninov, A A

    2010-01-01

    The balance of K+, Na+ and Cl- fluxes through cell membrane with the Na+/K+ pump, ion channels and NKCC and NC cotransporters is considered. It is shown that all unidirectional K+, Na+ and Cl- fluxes through cell membrane, permeability coefficients of ion channels and membrane potential can be computed for balanced ion distribution between cell and the medium if K+, Na+ and Cl- concentration in cell water and three fluxes are known: total Cl- flux, total K+ influx and ouabain-inhibitable "pump" component of the K+ influx. Changes in the mortovalent ion balance in lymphoid cells U937 induced to apoptosis by 1 microM staurosporine are analyzed as an example. It is found that the apoptotic shift in ion and water balance in studied cells is caused by a decrease in the pump activity which is accompanied by a decrease in the integral permeability of Na+ channels without significant increase in K+ and Cl- channel permeabilities. Computation shows that only a small part of the total fluxes of K+, Na+ and Cl- accounts for the fluxes via NKCC and NC cotransporters. Therefore, cotransport fluxes can not be studied using inhibitors.

  17. "Goldman Sachs-The Dark Side of Capitalism is Sometimes Unethical but Necessary"%高盛与美国政府:谁要道德?谁要效率?

    Institute of Scientific and Technical Information of China (English)

    泰德·普林斯

    2010-01-01

    @@ 美国政府正在对美国几家世界顶尖的金融机构采取刑事调查.高盛有罪与否?我看高盛是做了令人厌恶的事情,但它的行为并不违法.我们赞同高盛,因为高盛发展了抵押业务,并将其设计成对冲基金中最赚钱的"噱头".

  18. Biologist Edwin Grant Conklin and the idea of the religious direction of human evolution in the early 1920s.

    Science.gov (United States)

    Pavuk, Alexander

    2017-01-01

    Edwin Grant Conklin, renowned US embryologist and evolutionary popularizer, publicly advocated a social vision of evolution that intertwined science and modernist Protestant theology in the early 1920s. The moral prestige of professional science in American culture - along with Conklin's own elite scientific status - diverted attention from the frequency with which his work crossed boundaries between natural science, religion and philosophy. Writing for broad audiences, Conklin was one of the most significant of the religious and modernist biological scientists whose rhetoric went well beyond simply claiming that certain kinds of religion were amenable to evolutionary science; he instead incorporated religion itself into evolution's broadest workings. A sampling of Conklin's widely-resonant discourse suggests that there was substantially more to the religion-evolution story in the 1920s US than many creationist-centred narratives of the era imply.

  19. Biocompatibility and anti-microbiological activity characterization of novel coatings for dental implants: A primer for non-biologists

    Directory of Open Access Journals (Sweden)

    Thomas K Monsees

    2016-08-01

    Full Text Available With regard to biocompatibility, the cardinal requirement for dental implants and other medical devices that are in long-term contact with tissue is that the material does not cause any adverse effect to the patient. To warrant stability and function of the implant, proper osseointegration is a further prerequisite. Cells interact with the implant surface as the interface between bulk material and biological tissue. Whereas structuring, deposition of a thin film or other modifications of the surface are crucial parameters in determining favorable adhesion of cells, corrosion of metal surfaces and release of ions can affect cell viability. Both parameters are usually tested using in vitro cytotoxicity and adhesion assays with bone or fibroblasts cells. For bioactive surface modifications, further tests should be considered for biocompatibility evaluation. Depending on the type of modification, this may include analysis of specific cell functions or the determination of antimicrobial activities. The latter is of special importance as bacteria and yeast present in the oral cavity can be introduced during the implantation process and this may lead to chronic infections and implant failure. An antimicrobial coating of the implant is a way to avoid that. This review describes the essential biocompatibility assays for evaluation of new implant materials required by ISO 10993 and also gives an overview on recent test methods for specific coatings of dental implants.

  20. Microfluidics made easy: A robust low-cost constant pressure flow controller for engineers and cell biologists.

    Science.gov (United States)

    Mavrogiannis, Nicholas; Ibo, Markela; Fu, Xiaotong; Crivellari, Francesca; Gagnon, Zachary

    2016-05-01

    Over the last decade, microfluidics has become increasingly popular in biology and bioengineering. While lab-on-a-chip fabrication costs have continued to decrease, the hardware required for delivering controllable fluid flows to the microfluidic devices themselves remains expensive and often cost prohibitive for researchers interested in starting a microfluidics project. Typically, microfluidic experiments require precise and tunable flow rates from a system that is simple to operate. While many labs use commercial platforms or syringe pumps, these solutions can cost thousands of dollars and can be cost prohibitive. Here, we present an inexpensive and easy-to-use constant pressure system for delivering flows to microfluidic devices. The controller costs less than half the price of a single syringe pump but can independently switch and deliver fluid through up to four separate fluidic inlets at known flow rates with significantly faster fluid response times. It is constructed of readily available pressure regulators, gauges, plastic connectors and adapters, and tubing. Flow rate is easily predicted and calibrated using hydraulic circuit analysis and capillary tubing resistors. Finally, we demonstrate the capabilities of the flow system by performing well-known microfluidic experiments for chemical gradient generation and emulsion droplet production.

  1. Biocompatibility and anti-microbiological activity characterization of novel coatings for dental implants: A primer for non-biologists

    Science.gov (United States)

    Monsees, Thomas

    2016-08-01

    With regard to biocompatibility, the cardinal requirement for dental implants and other medical devices that are in long-term contact with tissue is that the material does not cause any adverse effect to the patient. To warrant stability and function of the implant, proper osseointegration is a further prerequisite. Cells interact with the implant surface as the interface between bulk material and biological tissue. Whereas structuring, deposition of a thin film or other modifications of the surface are crucial parameters in determining favorable adhesion of cells, corrosion of metal surfaces and release of ions can affect cell viability. Both parameters are usually tested using in vitro cytotoxicity and adhesion assays with bone or fibroblasts cells. For bioactive surface modifications, further tests should be considered for biocompatibility evaluation. Depending on the type of modification, this may include analysis of specific cell functions or the determination of antimicrobial activities. The latter is of special importance as bacteria and yeast present in the oral cavity can be introduced during the implantation process and this may lead to chronic infections and implant failure. An antimicrobial coating of the implant is a way to avoid that. This review describes the essential biocompatibility assays for evaluation of new implant materials required by ISO 10993 and also gives an overview on recent test methods for specific coatings of dental implants.

  2. Both Sides Now

    DEFF Research Database (Denmark)

    Pagh, Jesper

    2013-01-01

    Commentary on David Harvey: Spaces of Hope, Graham & Marvin: Splintering Urbanism and Hans Ibelings: Shifts......Commentary on David Harvey: Spaces of Hope, Graham & Marvin: Splintering Urbanism and Hans Ibelings: Shifts...

  3. Ecology, Diversity and Comparative Genomics of Oceanic Cyanobacterial Viruses

    Science.gov (United States)

    2004-06-01

    R., Gamier, M., Goldman, G. H., Goldman, M. H., Gomes, S. L., Gruber, A., Ho, P. L., Hoheisel, J. D., Junqueira , M. L., Kemper, E. L., Kitajima, J. P...M., Furlan, L. R., Gamier, M., Goldman, G. H., Goldman, M. H., Gomes, S. L., 153 Gruber, A., Ho, P. L., Hoheisel, J. D., Junqueira , M. L., Kemper, E

  4. Wolfgang Köhler and Gestalt theory: an English translation of Köhler's Introduction to die physischen Gestalten for Philosophers and Biologists.

    Science.gov (United States)

    Arnheim, R

    1998-02-01

    This article presents an English translation (from the German) of one of gestalt psychology's most significant documents, first published in 1920 in Wolfgang Kohler's Die physischen Gestalten in Ruhe und im stationdren Zustand (The Physical Gestalten at Rest and in a Stationary State). The book it introduces both embodies Kohler's extension of gestalt theory into new domains and did much to ensure the broad impact of these ideas and approaches. This introduction itself well illustrates Kohler's own thought processes both as his ideas emerged and as he sought to convince his readers of their value. Despite the fact that they are more than 70 years old, Kohler's words have many implications for late 20th century discussions of the relationships among psychology, physiology, and physics.

  5. "The awe in which biologists hold physicists": Frits Went's first phytotron at Caltech, and an experimental definition of the biological environment.

    Science.gov (United States)

    Munns, David P D

    2014-01-01

    After Darwin, experimental biology sought to unravel organisms. By the early twentieth century, organisms were broadly conceived as the product of their heredity and their environment. Much historical work has explored the scientific attack on the genotype, particularly through the new science of genetics. This article explores the tandem efforts to assert experimental control over the environment in which plants grew and developed. The case described here concerns the creation of the first phytotron at Caltech by botanist and plant physiologist Frits Went. Opening in 1949, the phytotron was a plant laboratory that, across a series of rooms and chambers, kept genes constant while regulating and maintaining defined ranges of known environments. This article details the context in which the phytotron emerged, how the phytotron gained its sobriquet, and how it served to cement the "environment" as a category of biological knowledge. Describing the institutional context of Caltech, its interdisciplinary culture, and its encouragement of adopting technology into biological science, I argue that the phytotron and the commensurate category of the "environment", were the product of the familiar movement to integrate the physical and biological sciences. In addition, however, the creation of the phytotron was also a broader story of plant physiologists establishing a definition of the "environment" in both physical and technological terms.

  6. Human radiation studies: Remembering the early years: Oral history of cell biologist Don Francis Petersen, Ph.D., conducted November 29, 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-08-01

    This report is a transcript of an interview of Dr. Don Francis Petersen by representatives of the US DOE Office of Human Radiation Experiments. Dr. Petersen was selected for this interview because of his long research career at Los Alamos and his knowledge of the Atomic Energy Commission`s biomedical program. Dr. Petersen did not personally conduct research on human subjects. After a brief biographical sketch Dr. Petersen discusses his remembrances of the early use of radionuclides as biological tracers, aspects of nuclear weapons testing in the 1940`s and 1950`s including fallout studies, the means by which research projects were approved, use of humans in the whole-body counter, and the Health Division Biomedical responsibilities.

  7. O papel do biólogo no gerenciamento do perigo aviário em aeroportos = The role of biologist in airport bird hazard management

    Directory of Open Access Journals (Sweden)

    Bezerra, George Christian Linhares

    2011-01-01

    Full Text Available A segurança operacional da aviação demanda o gerenciamento do perigo aviário. A maior parte dos eventos de colisão entre aves e aeronaves ocorre nas proximidades dos aeroportos, o que está relacionado à menor altitude de voo e concentração de aves devido a fatores atrativos. O artigo foca o papel do profissional de ciências biológicas no processo de gerenciamento do perigo aviário em aeroportos, tendo como objetivo descrever as atividades por ele executadas. A pesquisa consistiu de revisão da literatura, identificação da regulamentação aplicável e as práticas adotadas e, através de estudo de caso realizado em aeroporto localizado na região amazônica, foi possível coletar informações de interesse para a pesquisa. Os resultados apontam que o biólogo atua especificamente na identificação do perigo, identificando focos de atração de aves, espécies presentes e hábitos de comportamento. Além disso, assessora a avaliação de risco com informações sobre a probabilidade da ocorrência de colisões e sobre a gravidade das suas consequências

  8. ‘Spanish’ flu and army horses: what historians and biologists can learn from a history of animals with flu during the 1918–1919 influenza pandemic

    Directory of Open Access Journals (Sweden)

    Floor Haalboom

    2014-11-01

    Full Text Available At the time of the 1918–1919 ‘Spanish’ influenza pandemic, influenza researchers did not just relate this disease to the human population, despite the focus of historians of medicine on its human aspects and meanings. In line with the use of historical reports of animals with influenza in present-day microbiological studies on influenza among different animal species, this article investigates understandings of animal influenza in the Netherlands during the 1918–1919 pandemic. The article adds to microbiological uses of the historical record by putting observations of animals with influenza in historical contexts, in particular the context of military dealings with influenza at the end of the First World War, and the social position of veterinary medicine. The case of the Dutch military horse veterinarian Emile Bemelmans, who argued that human and horse influenza were identical, illustrates that knowledge of these contexts is important to critically use historical sources reporting animals with influenza in present-day biological influenza research.

  9. Dialysis

    Science.gov (United States)

    ... chap 132. Tolkoff-Rubin N. Treatment of irreversible renal failure. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: Elsevier Saunders; 2012:chap 133. Review Date 12/30/2014 Updated by: Deepak Sudheendra, ...

  10. Asbestosis

    Science.gov (United States)

    ... et al, eds. Murray and Nadel's Textbook of Respiratory Medicine. 6th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 73. Tarlo SM. Occupational lung disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  11. Industrial bronchitis

    Science.gov (United States)

    ... et al, eds. Murray and Nadel's Textbook of Respiratory Medicine . 5th ed. Philadelphia, PA: Elsevier Saunders; 2010:chap 64. Tarlo SM. Occupational lung disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  12. Silicosis

    Science.gov (United States)

    ... et al., eds. Murray and Nadel's Textbook of Respiratory Medicine . 6th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 73. Tarlo SM. Occupational lung disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  13. Bicuspid aortic valve

    Science.gov (United States)

    ... aortic disease. In: Otto CM, Bonow RO, eds. Valvular Heart Disease: A Companion to Braunwald's Heart Disease . 4th ed. ... PA: Elsevier Saunders; 2014:chap 13. Carabello BA. Valvular heart disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  14. Aortic insufficiency

    Science.gov (United States)

    ... page, please enable JavaScript. Aortic insufficiency is a heart valve disease in which the aortic valve does not close ... aortic insufficiency Images Aortic insufficiency References Carabello BA. Valvular heart disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  15. Mitral stenosis

    Science.gov (United States)

    ... can be prevented. Tell your provider about your heart valve disease before you receive any medical treatment. Discuss whether ... valves Heart valve surgery - series References Carabello BA. Valvular heart disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  16. Pulmonary valve stenosis

    Science.gov (United States)

    ... valvuloplasty - pulmonary Images Heart valves References Carabello BA. Valvular heart disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil ... Saunders; 2016:chap 69. Otto CM, Bownow RO. Valvular heart disease. In: Mann DL, Zipes DP, Libby P, Bonow ...

  17. Aortic stenosis

    Science.gov (United States)

    ... Images Aortic stenosis Heart valves References Carabello BA. Valvular heart disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil ... ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/ ...

  18. Tricuspid regurgitation

    Science.gov (United States)

    ... and dentist if you have a history of heart valve disease or congenital heart disease before treatment. Some people ... Regurgitation Tricuspid Regurgitation Ebstein's anomaly References Carabello BA. Valvular heart disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  19. Mitral valve regurgitation

    Science.gov (United States)

    ... and dentist if you have a history of heart valve disease or congenital heart disease before treatment. Some people ... the middle Heart, front view References Carabello BA. Valvular heart disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  20. Clean catch urine sample

    Science.gov (United States)

    ... specimen; Urine collection - clean catch; UTI - clean catch; Urinary tract infection - clean catch; Cystitis - clean catch ... LE, Norrby SR. Approach to the patient with urinary tract infection. In: Goldman L, Schafer AI, eds. Goldman-Cecil ...

  1. Aging changes in the breast

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/003999.htm Aging changes in the breast To use the sharing ... chap 198. Walston JD. Common clinical sequelae of aging. In: Goldman L, Schafer AI, eds. Goldman-Cecil ...

  2. Antistreptolysin O titer

    Science.gov (United States)

    ... of your heart A kidney problem called glomerulonephritis Rheumatic fever , which can affect the heart, joints, or bones ... chap 32. Low ED. Nonpneumoccal streptococcal infections and rheumatic fever. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  3. Enteral nutrition - child - managing problems

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/patientinstructions/000164.htm Enteral nutrition - child - managing problems To use the sharing features ... trouble breathing, call 911. References Mcclave SA. Enteral nutrition. In: Goldman L, Schafer AI, eds. Goldman-Cecil ...

  4. Amyotrophic lateral sclerosis (ALS)

    Science.gov (United States)

    Lou Gehrig disease; ALS; Upper and lower motor neuron disease; Motor neuron disease ... 98. Shaw PJ. Amyotrophic lateral sclerosis and other motor neuron diseases. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  5. Anaerobic bacteria

    Science.gov (United States)

    Brook I, Goldstein EJ. Diseases caused by non-spore forming anaerobic bacteria. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 297. Stedman's Online ...

  6. Reconstitution as a Guiding Principle to US Army Force Structure: High Risk or Prudent Hedge?

    Science.gov (United States)

    2014-05-20

    timely manner.”18 Marvin Kreidberg and Merton Henry’s classic survey of military mobilization from the nation’s inception through the end of World War...1992), 1. 19Marvin A. Kreidberg and Merton G. Henry, History of Military Mobilization in the United States Army, 1775-1945 (Washington DC: Department...treasure. In their comprehensive review of US Army Mobilization from 1775 to 1945, Army Officers Marvin Kreidberg and Merton Henry note "it has been

  7. [Uued heliplaadid] / Siim Nestor

    Index Scriptorium Estoniae

    Nestor, Siim, 1974-

    1999-01-01

    Heliplaatide tutvustus : Jamiroquai "Synkronized", Brandi Ifgray "Stargazer", Natalie Cole "Snowfall On the Sahara", Pizzicato Five "Playboy Playgirl", Erinevad esitajad "Marvin is 60 - A Tribute Album"

  8. Air and Space Power Journal. Volume 23, Number 3, Fall 2009

    Science.gov (United States)

    2009-01-01

    Darren K. Stanford Deputy Chief, Professional Journals Capt Lori Katowich Professional Staff Marvin W. Bassett, Contributing Editor Darlene H...Gunter Annex), Arnold (TN), Charleston (SC), Shaw (SC), Pope (NC), and Seymour Johnson (NC). 15. The adduced states include Maine, New Hampshire...Deputy Chief, Professional Journals Capt Lori Katowich Professional Staff Marvin W. Bassett, Contributing Editor Darlene H. Barnes, Editorial Assistant

  9. Domestic and Expeditionary Readiness in the Twenty-First Century: Maintaining an Operationalized Army National Guard

    Science.gov (United States)

    2012-12-06

    1974 (Washington, D.C.: U.S. Government Printing Office, 1997), 5. 11 Marvin A. Kreidberg and Merton G. Henry, Department of the Army Pamphlet 20-212...Kreidberg, Marvin A. and Merton G. Henry, Department of the Army Pamphlet 20-212, History of Military Mobilization in the United States Army: 1775-1945

  10. Mathematically Equivalent, Computationally Non-equivalent Formulas and Software Comprehensibility

    Science.gov (United States)

    2016-06-07

    and Software Comprehensibility Marvin J. Goldstein Surface Ship Sonar Department Approved for public release; distribution unlimited Report...equivalent Formulas and Software Comprehensibility 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Marvin Goldstein...13. SUPPLEMENTARY NOTES NUWC2015 14. ABSTRACT In the development of mathematical software , often the formula that defines the mathematical purpose

  11. 75 FR 56555 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2010-09-16

    ... Diego Rd, Berkeley, 10000812 MAINE Androscoggin County Webster Grammar School, 95 Hampshire St, Auburn... County Van Syckle, John, House, 195 Rummel Rd, Holland Township, 10000814 Middlesex County Goldman...

  12. Hemolytic anemia caused by chemicals and toxins

    Science.gov (United States)

    ... This list is not all-inclusive. Alternative Names Anemia - hemolytic - caused by chemicals or toxins References Michel M. Autoimmune and intravascular hemolytic anemias. In: Goldman L, Schafer ...

  13. Wildlife Species, ChukarPartridge-This dataset represents chukar partridge use areas in Utah as determined by wildlife biologists during 2001 - 2003., Published in 2004, 1:100000 (1in=8333ft) scale, State of Utah Automated Geographic Reference Center.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Wildlife Species dataset, published at 1:100000 (1in=8333ft) scale, was produced all or in part from Field Observation information as of 2004. It is described...

  14. Wildlife Species, Moose-This dataset represents moose use areas in Utah as determined by wildlife biologists during 2001., Published in 2004, 1:100000 (1in=8333ft) scale, State of Utah Automated Geographic Reference Center.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Wildlife Species dataset, published at 1:100000 (1in=8333ft) scale, was produced all or in part from Field Observation information as of 2004. It is described...

  15. Microorganisms and insects, the enemies of the past. Biologists, physicists, chemists, historians and geologists are fighting against the bio deterioration of the historical heritage; Biologos, Fisicos, Quimicos, Historiadores y Geologos luchan contra el biodeterioro del patrimonio historico

    Energy Technology Data Exchange (ETDEWEB)

    Almera, P.

    2015-07-01

    To continue enjoying trees and ancient property cultural is necessary to preserve them in good condition. With the passage of time, its backers - paper, parchment, wood or canvas - can be bio deterioration by your own composition or the environmental conditions to the they are subject. The damage could become irreparable. for this reason, specialists of all kinds of branches they combine knowledge and research to give with the formulas capable of alleviating alterations to properties chemical and mechanical provoked by the action of biological organisms over these materials. (Author)

  16. Wildlife Species, GambelsQuail-This dataset represents Gambel's Quail Habitat as determined by UDWR field biologists during the late 1980s., Published in 2004, 1:100000 (1in=8333ft) scale, State of Utah Automated Geographic Reference Center.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Wildlife Species dataset, published at 1:100000 (1in=8333ft) scale, was produced all or in part from Field Observation information as of 2004. It is described...

  17. Pop / Erik Morna

    Index Scriptorium Estoniae

    Morna, Erik, 1969-

    2003-01-01

    Heliplaatidest: Marvin Gaye"What's Going On", Dynamite Vikings featuring Pierre Dorge "Vikingology", Pet Shop Boys "Disco 3", erinevad esitajad "We're a Happy Family: A Tribute to the Ramones", Ozzy Osbourne "Essential"

  18. 76 FR 77728 - Process for a Designated Contract Market or Swap Execution Facility To Make a Swap Available To...

    Science.gov (United States)

    2011-12-14

    ... Roundtable, dated Mar. 8, 2011 at 8; Letter from R. Martin Chavez, Goldman, Sachs & Co., dated Mar. 8, 2011.... Martin Chavez, Goldman, Sachs & Co., dated Mar. 8, 2011 at 3; Letter from Craig Donohue, CME Group Inc... from Mark Vonderheide and Robert Creamer, Geneva Energy Markets, LLC, dated Jul. 29, 2011 at 2;...

  19. Development and Characterization of a High Speed Mid-IR Tunable Diode Laser Absorption Spectrometer for CO and CO2 Detection in Detonation Events

    Science.gov (United States)

    2014-03-27

    environments”. Applied Optics, 48(29):5546–5560, 2009. [24] Rothman , Larry S, CP Rinsland, A Goldman, ST Massie, DP Edwards, JM Flaud, A Perrin, C Camy...Quantitative Spectroscopy and Radiative Transfer, 60(5):665– 710, 1998. [25] Rothman , LS, IE Gordon, RJ Barber, H Dothe, RR Gamache, A Goldman, VI

  20. Development of a Small Molecule P2X7R Antagonist as a Treatment for Acute SCI

    Science.gov (United States)

    2013-10-01

    B., Goldman, S.A. Sustained induction of neuronal recruitment to the adult rat striatum by AAV4-delivered noggin and BDNF . Gene Therapy 19:483-93... stroke . Nature Medicine, 2014, in revision. Fox, I., Goldman, S.A., Huard, J., Kamp, T., Trucco, M. Pluripotential stem cells as therapy. Science

  1. The Contents of My Backpack

    Science.gov (United States)

    Goldman, Arthur

    2004-01-01

    As Mr. Goldman empties his backpack, his philosophy of teaching spills out, along with an interesting assortment of odds and ends. In this article Mr. Goldman describes the contents of his L.L. Bean daypack with two large compartments in the back, a smaller forward compartment, and a little zippered pocket in the very front, along with his…

  2. Developing High-Potential Youth Program: A Return on Investment Study for U.S. Programs

    Science.gov (United States)

    Millett, Catherine M.; Nettles, Michael T.

    2009-01-01

    When The Goldman Sachs Foundation (GSF) made its first strategic social investment decision in 1999, it took note of one of Goldman Sachs' core corporate values: People are its greatest asset. The program's objective was--and is--clear and simple: to increase the number of high-potential young adults from historically underrepresented backgrounds…

  3. Lung needle biopsy

    Science.gov (United States)

    ... biopsy Lung tissue biopsy References Ettinger DS. Lung cancer and other pulmonary neoplasms. In: Goldman L, Schafer AI, eds. Goldman's ... 2010:chap 47. Read More Aspiration ... by: Denis Hadjiliadis, MD, Associate Professor of Medicine, Pulmonary, Allergy, and Critical Care, Perelman School of Medicine, ...

  4. Achalasia

    Science.gov (United States)

    ... esophageal sphincter; LES; Myotomy Images Digestive system Upper gastrointestinal system Achalasia - series References Falk GW, Katzka DA. Diseases of the esophagus In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ... Gastrointestinal and Liver Disease . 10th ed. Philadelphia, PA: Elsevier ...

  5. Blood in the semen

    Science.gov (United States)

    ... semen URL of this page: //medlineplus.gov/ency/article/003163.htm Blood in the semen To use ... and look for signs of: Discharge from the urethra Enlarged or tender ... Saunders; 2016:chap 129. Small EJ. Prostate cancer. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  6. Congenital spherocytic anemia

    Science.gov (United States)

    ... blood cells, spherocytosis Blood cells References Gallagher PG. Red blood cell membrane disorders. In: Hoffman R, Benz EJ Jr, Silberstein LE, ... chap 43. Klatt EC, Kumar V. Hematopathology of red blood cells and bleeding disorders. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  7. Gastritis

    Science.gov (United States)

    ... and stomach lining References Kuipers E, Blaser MJ. Acid peptic disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: Elsevier Saunders; 2011:chap 141. Lee EL, Feldman M. Gastritis and gastropathies. In: Feldman ... Taking antacids Review Date 1/ ...

  8. Effective and Efficient Training and Advising in Pakistan

    Science.gov (United States)

    2010-06-01

    35 Marvin G. Weinbaum, “Counterterrorism, Regional Security, and Pakistan’s Afghan Frontier,” U.S. House of Representatives Armed Services...eating at a local food stand on October 2, 2002; SFC Christopher D. Shaw and SSG Jack M. Martin III were killed on September 29, 2009, when their...2008. http://www.time.com/time/world/article/0,8599,1842131,00.html, (accessed April 30, 2010). Weinbaum, Marvin G. “Counterterrorism, Regional

  9. Older men learning in the community : European snapshots

    OpenAIRE

    Radovan, Marko; Jelenc Krašovec, Sabina

    2014-01-01

    Contents: Preface: Older Men Learning in the Community – European Snapshots; Chapter 1: Introduction - Marvin Formosa, António Fragoso, Sabina Jelenc Krašovec, and Tiina Tambaum; Chapter 2: Older Men as Learners in the Community: Theoretical Issues - Marvin Formosa, António Fragoso, and Sabina Jelenc Krašovec; Chapter 3: Passing on Skills and Knowledge as Part of Learning for Older Men: Readiness and Obstacles among Older Men in the Municip...

  10. Scylla and Charybdis: the Army’s Development of War Plan Orange

    Science.gov (United States)

    2012-05-17

    Martin Kriedberg and First Lieutenant Merton Henry, places a primacy on the planning for the mobilization of manpower in case of war. Together, the...Infantry Journal Press, 1946), 290. 37 Marvin A. Kreidberg and Merton G. Henry, History of Military Mobilization in the United States Army, 1775...1920-1939. Lawrence, KS: University Press of Kansas, 1998. Kreidberg, Marvin A and Henry, Merton G. History of Military Mobilization in the United

  11. 调皮

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    2010年8月9日在美国德州大学的排球更衣室里,奥巴马的助理Marvin Nicholson在量体重奥巴马却调皮地在后面伸出一只脚为他增重,专心看表针的Marvin Nichotson完全没发觉引得众人直乐。

  12. The challenge of wolf recovery: an ongoing dilemma for state managers

    Science.gov (United States)

    Mech, L. David

    2013-01-01

    “Dave, would you do another legal declaration on the wolf for us?” The weary voice on the phone belonged to Mike Jimenez, Northern Rocky Mountain Wolf Management and Science Coordinator for the U.S. Fish and Wildlife Service (FWS). He was calling from Wyoming to ask me to prepare a document to address a legal challenge to the FWS’s August 2012 delisting of the wolf (Canis lupus) in Wyoming, a highly controversial move. Mike’s tone reflected the reality that — as so many wildlife biologists know and live each day — wildlife management is mainly people management. This contention could not be truer for managing any wildlife species than for managing the wolf. Dubbed “the beast of waste and desolation” by Teddy Roosevelt (The Wilderness Hunter 1893/1900), wolves had been universally hated as prolific predators of valuable livestock and game. Around the turn of the 20th century, members of the U.S. Biological Survey and various state agents, ranchers, cowboys, and other frontiersmen poisoned and persecuted wolves, extirpating them from most of the contiguous United States (Young and Goldman 1944). By 1967, Minnesota and nearby Isle Royale National Park in Michigan held the only remaining wolves in the Lower 48 states, prompting the FWS to place the wolf on the Endangered Species List (established by the Endangered Species Preservation Act of 1966). The wolf then became the list’s poster species, and the timing was ideal: Silent Spring (Carson 1962) had just seeded and fertilized the environmental movement, which blossomed on Earth Day (April 22, 1970) into the environmental revolution. “Save the wolf!” became one of the movement’s rallying cries. And save the wolf we did.

  13. Barrett esophagus

    Science.gov (United States)

    ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 138. Ferri FF. Barrett esophagus. ... FF, ed. Ferri's Clinical Advisor 2016 . Philadelphia, PA: Elsevier; 2016:202-203. Katz PO, Gerson LB, Vela ...

  14. Cardiomyopathy

    Science.gov (United States)

    ... Textbook of Cardiovascular Medicine . 10th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 65. McKenna WJ, Elliott P. ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 60. McMurray JJV, Pfeffer MA. ...

  15. Daily bowel care program

    Science.gov (United States)

    ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 136. Koyle MA, Lorenzo AJ. ... eds. Campbell-Walsh Urology . 11th ed. Philadelphia, PA: Elsevier; 2016:chap 144. Lembo AJ. Constipation. In: Feldman ...

  16. Arteriogram

    Science.gov (United States)

    ... eds. Rutherford's Vascular Surgery . 8th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 102. Goldstein LB. Approach to ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 406. Kern M. Catheterization and ...

  17. Hemolysis

    Science.gov (United States)

    ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 161. Gallagher PG. Red blood ... Basic Principles and Practice . 6th ed. Philadelphia, PA: Elsevier; 2013:chap 43. Michel M. Autoimmune and intravascular ...

  18. Culture - colonic tissue

    Science.gov (United States)

    ... Management by Laboratory Methods . 23rd ed. Philadelphia, PA: Elsevier; 2017:chap 64. DuPont HL. Approach to the ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 283. Hall GS, Woods GL. ...

  19. Head lice

    Science.gov (United States)

    ... Practice of Infectious Diseases . 8th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 294. Elston DM. Arthropods and ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 359 Habif TP. Infestations and ...

  20. Smear of duodenal fluid aspirate

    Science.gov (United States)

    ... Management by Laboratory Methods . 23rd ed. Philadelphia, PA: Elsevier; 2017:chap 64. Dupont HL. Approach to the ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 283. Fritsche TR, Pritt BS. ...

  1. Giardia infection

    Science.gov (United States)

    ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 283. Haines CF, Sears CL. ... Gastrointestinal and Liver Disease . 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 110. Nash TE, Hill DR. ...

  2. Digitalis toxicity

    Science.gov (United States)

    ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 110. Cole JB, Roberts DJ. ... Concepts and Clinical Practice . 8th ed. Philadelphia, PA: Elsevier Saunders; 2013:chap 152. Goldberger AL, Goldberger ZD, ...

  3. Hepatitis

    Science.gov (United States)

    ... Gastrointestinal and Liver Disease. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 90. Pawlotsky J-M. Chronic ... eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 149. Sjogren MH, Bassett JT. ...

  4. Lead poisoning

    Science.gov (United States)

    ... ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 157. Woolf AD, Goldman R, Bellinger DC. Update on the clinical ... by: Jacob L. Heller, MD, MHA, Emergency Medicine, Virginia Mason Medical Center, Seattle, WA. Also reviewed by ...

  5. Campylobacter serology test

    Science.gov (United States)

    ... time the skin is broken) Images Blood test Campylobacter jejuni organism References Allos BM. Campylobacter infections. In: Goldman ... chap 303. Allos BM, Iovine NM, Blaser MJ. Campylobacter jejuni and related species. In: Bennett JE, Dolin R, ...

  6. Genetics Home Reference: Fabry disease

    Science.gov (United States)

    ... AJ, Germain DP, Goldman M, Grabowski G, Packman S, Wilcox WR. Fabry disease, an under-recognized multisystemic disorder: ... Sims K, Brodie SE, Pastores GM, Strotmann JM, Wilcox WR. Fabry disease: guidelines for the evaluation and ...

  7. Vanameister avas rahalaeka / Silvia Viidik

    Index Scriptorium Estoniae

    Viidik, Silvia, 1972-

    2008-01-01

    Warren Buffett ulatas abikäe investeerimispangale Goldman Sachs, investeerides sinna 5 miljardit dollarit ning tõttas appi General Electricule, kuhu investeeris 3 miljardit dollarit. Vt. samas: Warren Buffett; Berkshire Hathaway

  8. 75 FR 17803 - Self-Regulatory Organizations; NASDAQ OMX PHLX, Inc.; Notice of Filing and Immediate...

    Science.gov (United States)

    2010-04-07

    ... Company (``GE''); Goldman Sachs Group, Inc. (``GS''); Microsoft Corporation (``MSFT''); Qualcomm, Inc... Devices, Inc. (``AMD''); AMR Corporation (``AMR''); Caterpillar, Inc. (``CAT''); Cisco Systems, Inc... Financial Bear 3X Shares (``FAZ''); SPDR Gold Trust (``GLD''); Intel Corporation (``INTC''); JPMorgan...

  9. Bricking a Regime

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    When Goldman Sachs created the acronym BRIC in 2001,neither the economists nor the rest of the world imagined that Brazil,Russia,India and China would finally sit together to build up a substantial platform one day.

  10. What We Know and Do Not Know about the Functions of the Orbitofrontal Cortex after 20 Years of Cross-Species Studies

    OpenAIRE

    Murray, Elisabeth A.; O'Doherty, John P.; Schoenbaum, Geoffrey

    2007-01-01

    When Pat Goldman-Rakic described the circuitry and function of primate prefrontal cortex in her influential 1987 monograph (Goldman-Rakic, 1987), she included only a few short paragraphs on the orbitofrontal cortex (OFC). That year, there were only nine papers published containing the term “orbitofrontal,” an average of less than one paper per month. Twenty years later, this rate has increased to 32 papers per month. This explosive growth is partly attributable to the remarkable similarities ...

  11. Root Cause Investigation (RCI) Best Practices Guide Product Overview

    Science.gov (United States)

    2014-05-08

    Tracy Fiedler Raytheon tracy.m.fiedler@raytheon.com Brad Fields Orbital fields.brad@orbital.com Sherri Fike Ball sfike@ball.com Richard Fink NRO...michael.j.sampson@nasa.gov Victor Sank NASA victor.j.sank@nasa.gov Don Sawyer AVNET don.sawyer@avnet.com Fred Schipp MDA - Navy frederick.schipp@navy.mil...ghislain.turgeon@sslmda.com Deborah Valley MIT deborah.valley@ll.mit.edu Fred Van Milligen JDSU fvanmilligen@jdsu.com Marvin VanderWeg SpaceX marvin.vanderwag

  12. Root Cause Investigation Best Practices Guide

    Science.gov (United States)

    2014-05-30

    James Farrell james.t.farrell@boeing.com Boeing Tracy Fiedler tracy.m.fiedler@raytheon.co m Raytheon Brad Fields fields.brad@orbital.com Orbital...Sawyer don.sawyer@avnet.com AVNET Fred Schipp frederick.schipp@navy.mil MDA - Navy Jim Schultz james.w.schultz@boeing.co m Boeing Gerald Schumann... Fred Van Milligen fvanmilligen@jdsu.com JDSU Marvin VanderWeg marvin.vanderwag@spacex.c om SpaceX Gerrit VanOmmering gerrit.vanommering@sslmda. com SSL

  13. When old technologies were new thinking about electric communication in the late nineteenth century

    CERN Document Server

    Marvin, Carolyn

    1990-01-01

    In the history of electronic communication, the last quarter of the nineteenth century holds a special place, for it was during this period that the telephone, phonograph, electric light, wireless, and cinema were all invented. In When old Technologies Were New, Carolyn Marvin explores howtwo of these new inventions--the telephone and the electric light--were publicly envisioned at the end of the nineteenth century, as seen in specialized engineering journals and popular media. Marvin pays particular attention to the telephone, describing how it disrupted established socialrelations, unsettl

  14. Analysis of United States Air Forces Central Government Purchase Card Reachback Viability

    Science.gov (United States)

    2011-12-01

    Kiser HQ ACC – A7/K Langley AFB, VA 7. Col Marvin Smith HQ AFCENT – A7 Shaw AFB, SC 8. Lt Col Timothy Hawkins Naval Postgraduate School...Colonel Marvin Smith – for providing the necessary resources for us to go on the PMA trip • Colonel Scott Kiser – for selecting us to accompany Maj...closest to the originating location of the supply chain, which is usually in the contiguous United States. USAFCENT, based out of Shaw Air Force Base

  15. IEEE Life Cycle Standards and the CMMI(Trademark) - Implementation Considerations

    Science.gov (United States)

    2008-06-16

    Maloney CH 1l43{) R. N. Haddad M5-689 D. C. Marvin M I-003 L. F. Halle CHI-530 L. S. Marvin M6-2W4 P. Hantos Ml-1 12 J. F. McNeil MI-178 FINAL...M4-021 R. P. Sena M5-688 H. M. Shao M8-691 B. E. Shaw M5-564 I. S. Shrater M3-432 F. J. Sisti M8-018 D. M. Speckamn M 1-003 B . Springsteen CH 1-402

  16. Fifty challenging problems in probability with solutions

    CERN Document Server

    Mosteller, Frederick

    1987-01-01

    Can you solve the problem of ""The Unfair Subway""? Marvin gets off work at random times between 3 and 5 p.m. His mother lives uptown, his girlfriend downtown. He takes the first subway that comes in either direction and eats dinner with the one he is delivered to. His mother complains that he never comes to see her, but he says she has a 50-50 chance. He has had dinner with her twice in the last 20 working days. Explain. Marvin's adventures in probability are one of the fifty intriguing puzzles that illustrate both elementary ad advanced aspects of probability, each problem designed to chall

  17. Wildlife Species, SageGrouseWinter-This dataset represents Sage-grouse winter use areas in Utah as determined by UDWR field biologists in spring 1999., Published in 2004, 1:100000 (1in=8333ft) scale, State of Utah Automated Geographic Reference Center.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Wildlife Species dataset, published at 1:100000 (1in=8333ft) scale, was produced all or in part from Field Observation information as of 2004. It is described...

  18. Wildlife Species, SageGrouseBroodingAreas-This data set represents Sage-grouse brooding use areas in Utah as determined by UDWR field biologists in spring 1999., Published in 2004, 1:100000 (1in=8333ft) scale, State of Utah Automated Geographic Reference Center.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Wildlife Species dataset, published at 1:100000 (1in=8333ft) scale, was produced all or in part from Field Observation information as of 2004. It is described...

  19. Wildlife Species, RockyMountainBigHornSheep-This dataset represents Rocky Mountain bighorn sheep use areas in Utah as determined by wildlife biologists during 2001., Published in 2004, 1:100000 (1in=8333ft) scale, State of Utah Automated Geographic Reference Center.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Wildlife Species dataset, published at 1:100000 (1in=8333ft) scale, was produced all or in part from Field Observation information as of 2004. It is described...

  20. Wildlife Species, SharpTailedGrouse-This dataset represents Sharp-tailed Grouse use areas in Utah as determined by wildlife biologists during 2000., Published in 2004, 1:100000 (1in=8333ft) scale, State of Utah Automated Geographic Reference Center.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Wildlife Species dataset, published at 1:100000 (1in=8333ft) scale, was produced all or in part from Field Observation information as of 2004. It is described...

  1. Wildlife Species, WildTurkey-This dataset represents Rio Grande and Merriam's Wild Turkey use areas in Utah as determined by wildlife biologists during 2001 through 2003., Published in 2004, 1:100000 (1in=8333ft) scale, State of Utah Automated Geographic Reference Center.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Wildlife Species dataset, published at 1:100000 (1in=8333ft) scale, was produced all or in part from Field Observation information as of 2004. It is described...

  2. Wildlife Species, DesertBigHornSheep-This dataset represents desert bighorn sheep use areas in Utah as determined by wildlife biologists during 2001, with supplemental additions motivated by the Richfield BLM Resource Management Planning process in the spring of 2004, in N, Published in 2005, 1:100000 (1in=8333ft) scale, State of Utah Automated Geographic Reference Center.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Wildlife Species dataset, published at 1:100000 (1in=8333ft) scale, was produced all or in part from Field Observation information as of 2005. It is described...

  3. Wildlife Species, CaliforniaBigHornSheep-This dataset represents California bighorn sheep use areas in Utah as determined by wildlife biologists during 2001., Published in 2004, 1:100000 (1in=8333ft) scale, State of Utah Automated Geographic Reference Center.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Wildlife Species dataset, published at 1:100000 (1in=8333ft) scale, was produced all or in part from Field Observation information as of 2004. It is described...

  4. Wildlife Species, CaliforniaQuail-This dataset represents California Quail use areas as determined by UDWR field biologists during the late 1980s., Published in 2004, 1:100000 (1in=8333ft) scale, State of Utah Automated Geographic Reference Center.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Wildlife Species dataset, published at 1:100000 (1in=8333ft) scale, was produced all or in part from Field Observation information as of 2004. It is described...

  5. A Manual for the Performance of Protective Equipment Fit-Mapping

    Science.gov (United States)

    2009-10-01

    26 Figure 16. Four different sizes on one model ...Authors appreciate Dr. Bruce Bradtmiller, Dr. Marvin Dainoff, Dr. Hongwei Hsiao, Ms. Teresa Metzger, Mr. Ken Waugh, and Ms. Jenny Whitestone for...the method. They are “girth ease allowance” and “radial ease allowance”. Girth ease allowance is the amount of ease measured the common way (by tuck

  6. Operation Outreach. National Network for Curriculum Coordination in Vocational-Technical Education. Conference Proceedings (Denver, Colorado, July 9-13, 1979).

    Science.gov (United States)

    National Network for Curriculum Coordination in Vocational and Technical Education.

    Proceedings are presented of the National Network for Curriculum Coordination Conference, which focused on coordinating within the Network and expanding services to vocational educators. The conference keynote address, by Marvin Feldman, was Futurism - A Technical Revolution. Other items included were (1) presentations on the National Network for…

  7. Beyond Hierarchy: The Search for High Performance.

    Science.gov (United States)

    Galagan, Patricia A.; And Others

    1992-01-01

    This special report of the reorganization of work looks at approaches to organizational renewal that are challenging the notion of the hierarchy as the only form that works. Looks at models for organizing work presented by Gary Rummler, D. Quinn Mills, and Marvin Weisbord and a blueprint for creating common futures with large groups of people.…

  8. Memoir of the Long Range Acoustic Propagation Program (LRAPP)

    Science.gov (United States)

    2011-04-01

    Experiment At that time, this experiment was unique. VADM Harold Shear (OP-095) and CAPT Vern Anderson, PME-124 at that time (PME –program manager, Naval...They were built in ONR and the Navy laboratories. The man who had the vision was Dr. Marvin Lasky , who is probably entitled to be designated the

  9. 76 FR 37358 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2011-06-27

    ... applications and the discussions could disclose confidential trade secrets or commercial property such as... Person: Marvin L. Salin, PhD, Scientific Review Officer, Special Review and Logistics Branch, Division of...., Scientific Review Officer, Special Review and Logistics Branch, Division of Extramural Activities,...

  10. Islam, Islamism, and Democratic Values. Footnotes. Volume 11, Number 4

    Science.gov (United States)

    Kuehner, Trudy

    2006-01-01

    On May 6-7, 2006 FPRI's Marvin Wachman Fund for International Education hosted 44 teachers from 16 states across the country for a weekend of discussion on teaching about Islam. Speakers were drawn from the disciplines of religious studies, anthropology, political science, history, law, and journalism. The institute, held in Bryn Mawr, Pa., was…

  11. Development of a Design Tool for Planning Aqueous Amendment Injection Systems

    Science.gov (United States)

    2012-08-01

    provided by Andrea Leeson (Environmental Restoration Program Manager), Hans Stroo (ESTCP reviewer), Marvin Unger (ESTCP reviewer), and the many long...Pohlmann, Shaw Group, Inc. • Eliot Cooper, Vironex, Inc. • Erica Becvar, Air Force Center for Environmental Engineering • Fritz Krembs, TriHydro

  12. Performance Results for the Optical Turbulence Reduction Cavity (Postprint)

    Science.gov (United States)

    2008-12-01

    DR. RYAN F. SCHMIT, Aerospace Engineer MARVIN C. GRIDLEY, Acting Chief Aerospace Vehicle Integration and Aerospace Vehicle Integration and...Many studies including Heller and Bliss,3 Kaufman and Clark,4 Shaw et al.,5 Sarno and Franke6 have examined zero-frequency devices like spoilers to

  13. From the Andes to the Hindu Kush: Columbian Airpower Lessons for Afghanistan

    Science.gov (United States)

    2010-05-20

    81 Nadir Shaw in 1930 was quite brutal in general and used airpower to put down Afghans in Kohistan.82 After the relatively peaceful ―golden age‖ of...Leavenworth: United States Army Command and General Staff College, 1996. Pugmire, Marvin S., Lt Col. Unconventional Airmen: Present and Future

  14. 世界管理大师连载之(7)平衡记分卡创始人:罗伯特·卡普兰

    Institute of Scientific and Technical Information of China (English)

    赵娟

    2007-01-01

    @@ 罗伯特·卡普兰(Robert S.Kaplan),是平衡记分卡(Balanced Scorecard,简称BSC)的创始人,现执教于哈佛商学院领导力开发专业之Marvin Bower教席,担任哈佛教职已达18年.

  15. Information Systems: Current Developments and Future Expansion.

    Science.gov (United States)

    1970

    On May 20, 1970, a one-day seminar was held for Congressional members and staff. The papers given at this seminar and included in the proceedings are: (1) "Understanding Information Systems" by J. D. Aron, (2) "Computer Applications in Political Science" by Kenneth Janda, (3) "Who's the Master of Your Information System?" by Marvin Kornbluh, (4)…

  16. Impact of Diversity on the Civil-Military Relationship

    Science.gov (United States)

    2013-05-23

    Huntington, 165. 38 Marvin Kriedberg and Henry Merton , History of Military Mobilization in the United States Army, Department of the Army, November 1955...and Merton , 192-194. 49 Millett and Maslowski, 471 50 Johnson and Metz, 210. 17... Merton , 239-246. 86 Ibid., 239-246. 87 Griffith and Griffith Jr., 6-13. 88 Ibid. 30 the

  17. Jane Austen: A Collection of Critical Essays. Twentieth Century Views Series.

    Science.gov (United States)

    Watt, Ian, Ed.

    One of a series of works aimed at presenting contemporary critical opinion on major authors, this collection includes essays by Virginia Woolf, C. S. Lewis, Edmund Wilson, Ian Watt, Alan D. McKillop, Reuben A. Brower, Marvin Mudrick, Mark Schorer, Arnold Kettle, Lionel Trilling, Kingsley Amis, Andrew H. Wright, Donald J. Greene, and D. W.…

  18. Evaluation of Plane-of-Light Noninterference Stress Measurement Systems for Measuring Bladed Disk Vibrations

    Science.gov (United States)

    1989-12-24

    has been reviewed anJ is approved for publica - tion. JOHD REED, Aerospaeo Engineer MARVIN F. SCHMIDT, ChiefPrJ ion Integration Engine Integration...Zz~At)w LUz (1ts, W 5 TIME Pulse One Pulse Two GOt) 41at 21 V alt) a -A w2 ian T I Figure 20. Pulse Locations on Sine Wave for Double Pulse

  19. Research on a Frame-Based Model of Reading Comprehension. Final Report.

    Science.gov (United States)

    Goldstein, Ira

    This report summarizes computational investigations of language comprehension based on Marvin Minsky's theory of frames, a recent advance in artifical intelligence theories about the representation of knowledge. The investigations discussed explored frame theory as a basis for text comprehension by implementing models of the theory and developing…

  20. The Reference Encounter Model.

    Science.gov (United States)

    White, Marilyn Domas

    1983-01-01

    Develops model of the reference interview which explicitly incorporates human information processing, particularly schema ideas presented by Marvin Minsky and other theorists in cognitive processing and artificial intelligence. Questions are raised concerning use of content analysis of transcribed verbal protocols as methodology for studying…

  1. 76 FR 22939 - 30-Day Notice of Proposed Information Collection: Form- DS-1950, Department of State Application...

    Science.gov (United States)

    2011-04-25

    ... selections, in accordance with Federal policies. Dated: April 5, 2011. Ruben Torres, Director, HR/EX... collection. Originating Office: Bureau of Human Resources, Office of Recruitment, Examination, Employment (HR... from Marvin E. Moore, Bureau of Human Resources, Recruitment Division, Student Programs,...

  2. Applications of Neural Networks in Fault Detection of Rotating Machinery

    Science.gov (United States)

    1993-05-17

    based on the ADALINE (ADAptive LINear Element) perceptron [Ref #4]. They correctly theorized that it would be possible for their 7 network to...Marvin Minski and Seymour Pappert [Ref #5]. After extensive mathematical study, Minski and Pappert concluded that a neural network based on the ADALINE

  3. Projects, Products and Services: Celebrating 75 Years of Excellence

    Science.gov (United States)

    2009-01-01

    underground command center of the North American AeroSpace Defense and United States Space Commands. Sharing the complex with NORAD are the Missile...Ralph E Rader Chief, Military Design Branch, Engineering 1946-1968 Distinguished Civilians Marvin A. Bromberg Denver Resident Engineer

  4. The Arts 3D VLE Metaverse as a Network of Imagination

    Science.gov (United States)

    Rauch, Ulrich; Cohodas, Marvin; Wang, Tim

    2009-01-01

    Ulrich Rauch, Marvin Cohodas, and Tim Wang describe the Arts Metaverse, a Croquet-based virtual learning environment under development at the University of British Columbia. The Arts Metaverse allows three-dimensional virtual reconstruction of important artifacts and sites of classical, ancient, and indigenous American art, thereby allowing…

  5. Water and Security in the Jordan Basin

    Science.gov (United States)

    1992-06-11

    political, and diplomatic strengths. For this reason alone, it serves as an excellent tool for working on the problems of the Jordan basin. 561...and Brdens:L R pr cm the West Bank and Gaza rip Ecnmi since 1967. New York: Carnegie Endowment, 1977. Weinbaum, Marvin G. F Devopment and Politing in

  6. Pilot-Scale Electrochemical Synthesis of Potassium 2,2-Dinitroethanate

    Science.gov (United States)

    2011-01-01

    Paraskos Marvin Hawkins ATK Launch Systems Tedd Lister Robert Fox Idaho National Labs Peter Symons Electrosynthesis Inc. REPORT...production‐scale  EC  cells  and  operation.  Peter  Symons : info@electrosynthesis.com           

  7. Cloud Chemistry of Fallout Formation

    Science.gov (United States)

    1968-01-31

    reasonable to study by the vaporization method. In the diffusion experimento it has been found necessary to maintain an ambient pressure of a few hundred...Illinois 61803 Project Superviseo, Marvin Polan Ford Inistrument C~ompany Mr. Charles Eisenhauer 31-01 Thomson Avenue National Bure~iu of Standards Long

  8. 77 FR 1688 - Notice of Debarment

    Science.gov (United States)

    2012-01-11

    ... FCC Rcd 11389 (Inv. & Hearings Div., Enf. Bur. 2011). \\3\\ 76 FR 54768 (September 2, 2011). \\4\\ Supra... obstructed the open competitive bidding process by paying school officials $79,382 in bribes and kickbacks to..., Antitrust Division, United States Department of Justice (via email) Marvin Opotowsky, Antitrust...

  9. 75 FR 70952 - Proposal Review Panel for Physics; Notice of Meeting

    Science.gov (United States)

    2010-11-19

    ... From the Federal Register Online via the Government Publishing Office NATIONAL SCIENCE FOUNDATION Proposal Review Panel for Physics; Notice of Meeting In accordance with the Federal Advisory Committee Act...: Partially Closed. Contact Person: Dr. Marvin Goldberg, Program Director for Elementary Particle...

  10. Teaching India. Footnotes. Volume 11, Number 2

    Science.gov (United States)

    Kuehner, Trudy

    2006-01-01

    On March 11-12, 2006 the FPRI's Marvin Wachman Fund for International Education hosted 44 teachers from 16 states across the country for a weekend of discussion on teaching about India. Sessions included: (1) Why It's Important to Know about India (Ainslie T. Embree); (2) Early Indian History (Richard H. Davis); (3) Modern Indian History (Marc…

  11. Measuring Managerial Potential and Intervening to Improve the Racial Equity of Upward Mobility Decisions.

    Science.gov (United States)

    1985-04-01

    h RING AZ[wCV NAME 6 AONEI(JSSfi diiieronrt ie Centrollng Office) I. SECURITY CLASS. (ol f lOo roport) lISe *CC, ASSIPICATION ’ DOWNGRADING...56, 81-105. Campbell, John P., Dunnette, Marvin D., Lawler, Edward E., III, and Weick, Karl E. Managerial Behavior Performance and Effectiveness. New

  12. Incidental observations on the birds of Amchitka Island, Alaska 9 September to 18 September, 1987

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Fish and Wildlife Service Volunteer Biologist Kevin Reyer and SCA biologist William Penning visited Amchitka Island, Alaska from 9 September to 18 September 1987...

  13. Moose Survey Report

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Aerial counts in fall, winter, and spring by Department biologists and by biologists of cooperating agencies (U.S. Forest Service, and U.S. Fish and Wildlife...

  14. Emergency Operations Center ribbon cutting

    Science.gov (United States)

    2009-01-01

    Center Director Gene Goldman and special guests celebrate the opening of the site's new Emergency Operations Center on June 2. Participants included (l t r): Steven Cooper, deputy director of the National Weather Service Southern Region; Tom Luedtke, NASA associate administrator for institutions and management; Charles Scales, NASA associate deputy administrator; Mississippi Gov. Haley Barbour; Gene Goldman, director of Stennis Space Center; Jack Forsythe, NASA assistant administrator for the Office of Security and Program Protection; Dr. Richard Williams, NASA chief health and medical officer; and Weldon Starks, president of Starks Contracting Company Inc. of Biloxi.

  15. Common Features and Differences

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    @@ Lin: From the discussion above, the BRICs have favorable conditions to ensure rapid development as well as restricting factors that hinder rapid growth. Many of the favorable and unfavorable conditions are nearly the same. It seems reasonable for the Goldman & Sachs to put the four countries together and coin a new word. But obviously Goldman & Sachs Co. regards the BRICs as a new group in the international arena; it is also true for the West media and some analysts in particular. Next, let us discuss whether Brazil, Russia, India and China could form a group, or is it possible for them to form an international political and economic group that takes concerted action?

  16. Fillers for the improvement in acne scars

    Directory of Open Access Journals (Sweden)

    Wollina U

    2015-09-01

    Full Text Available Uwe Wollina,1 Alberto Goldman2 1Department of Dermatology and Allergology, Academic Teaching Hospital, Dresden-Friedrichstadt, Dresden, Germany; 2Clinica Goldman, Porto Alegre, Rio Grande do Sul, Brazil Abstract: Acne is a common inflammatory disease. Scarring is an unwanted end point of acne. Both atrophic and hypertrophic scar types occur. Soft-tissue augmentation aims to improve atrophic scars. In this review, we will focus on the use of dermal fillers for acne scar improvement. Therefore, various filler types are characterized, and available data on their use in acne scar improvement are analyzed. Keywords: acne, scars, dermal fillers, injection, extracellular matrix

  17. What we know and do not know about the functions of the orbitofrontal cortex after 20 years of cross-species studies.

    Science.gov (United States)

    Murray, Elisabeth A; O'Doherty, John P; Schoenbaum, Geoffrey

    2007-08-01

    When Pat Goldman-Rakic described the circuitry and function of primate prefrontal cortex in her influential 1987 monograph (Goldman-Rakic, 1987), she included only a few short paragraphs on the orbitofrontal cortex (OFC). That year, there were only nine papers published containing the term "orbitofrontal," an average of less than one paper per month. Twenty years later, this rate has increased to 32 papers per month. This explosive growth is partly attributable to the remarkable similarities that exist in structure and function across species. These similarities suggest that OFC function can be usefully modeled in nonhuman and even nonprimate species. Here, we review some of these similarities.

  18. Hancock County Awards Gala

    Science.gov (United States)

    2008-01-01

    Gene Goldman (left), deputy director of NASA's John C. Stennis Space Center, accepts an Award of Excellence from Jack Zink, executive director of the Hancock County Port and Harbor Commission, during the 2008 Annual Hancock County Awards Gala. The Award of Excellence was presented to recognize Stennis Space Center's contribution to NASA's 50 years of excellence in space exploration.

  19. Oh No, Not the "A" Word! Proposing an "Anarchism" for Education

    Science.gov (United States)

    DeLeon, Abraham

    2008-01-01

    Anarchist theory has a long-standing history in political theory, sociology, and philosophy. As a radical discourse, anarchist theory pushes educators and researchers towards new conceptualizations of community, theory, and praxis. Early writers, like Joseph Proudhoun and Emma Goldman, to more contemporary anarchists, such as Noam Chomsky, have…

  20. 78 FR 20918 - Consumer Advisory Committee

    Science.gov (United States)

    2013-04-08

    ... Chairperson) *Partners Healthcare--Dr. Julian Goldman *Qualcomm Incorporated--Robert Jarrin Rochester Institute of Technology--Raja Kushalnagar Speech Communication Assistance by Telephone--Rebecca Ladew Time Warner Cable--Fernando R. Laguarda T-Mobile--Luisa Lancetti Verizon Communications, Inc.--Donna Rynex...

  1. DMPD: Protein kinase C epsilon: a new target to control inflammation andimmune-mediated disorders. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 14643884 Protein kinase C epsilon: a new target to control inflammation andimmune-mediated diso...g) (.html) (.csml) Show Protein kinase C epsilon: a new target to control inflammation andimmune-mediated diso...l inflammation andimmune-mediated disorders. Authors Aksoy E, Goldman M, Willems F. Publication Int J Bioche

  2. Medical Device Plug-and-Play Interoperability Standards and Technology Leadership

    Science.gov (United States)

    2014-10-01

    Society of Anesthesiology Newsletter 70:5, May 2006. 3. Goldman JM, “Patient-Centric Networked Medical Device Interoperability,” part of Dagalakis NG...Interoperability Movement,” Anesthesiology News 34:12, December 2008. 19. Johnson C, “Medical devices lag in iPod age,” The Boston Globe, December 29 2008. 20

  3. Expeditionary Economics: The Military’s Role in Conflict-Related Development

    Science.gov (United States)

    2012-06-08

    99 (New York: The Goldman Sacs Group, Inc., 2003); Robert Solow , “A Contribution to the Theory of Economic Growth,” Quarterly Journal of Economics......Director, Graduate Degree Programs Robert F. Baumann, Ph.D. The opinions and conclusions expressed herein are those of the student author and

  4. Manifestations of the MOMM Phenomenon II: Relevant Data on Professional Darwinism and Membership Composition.

    Science.gov (United States)

    Horan, John J.; And Others

    Horan (1989) reported that graduates and employees of four institutions (Minnesota, Ohio State, Maryland, and Missouri - the "MOMM Cartel") heavily dominate every science and practice organ of the American Psychological Association's Division 17 governing body. Goldman (1990) provided additional data indicating that egregious exclusion…

  5. O'Neill: majanduse uut tõusu hakkavad vedama 15 riiki

    Index Scriptorium Estoniae

    2010-01-01

    Goldman Sachsi varahalduse juhi Jim O'Neilli hinnangul kujuneb keskmise ja suure tulu saajate arvu dramaatiline kasv BRIC-riikides (Brasiilia, Venemaa, India, Hiina) ja N-11 riikides (Mehhiko, Türgi, Korea, Iraan, Egiptus, Nigeeria, Pakistan, Filipiinid, Bangladesh, Vietnam) suurimaks tarbimist vedavaks jõuks maailmas lähema 10 aasta jooksul ja sealt edasi

  6. Incorporating Feminist Standpoint Theory

    DEFF Research Database (Denmark)

    Ahlström, Kristoffer

    2005-01-01

    As has been noted by Alvin Goldman, there are some very interesting similarities between his Veritistic Social Epistemology (VSE) and Sandra Harding’s Feminist Standpoint Theory (FST). In the present paper, it is argued that these similarities are so significant as to motivate an incorporation...

  7. The Army of the 1990’s Women’s Leadership Role.

    Science.gov (United States)

    1988-04-27

    HYistorical and Con temarary Vr=pective p. 223. * 26 20. Nancy Loring Goldman in colaboration with Karl L. Wiegard, The Utilization of Women in Combat...Seminar on Armed Forces and Society, Univ. of Chicago) in colaboration with Wiegand, Karl L. (Temple Hills, Maryland) The Utzlization of Women in

  8. Coming to See Objects of Knowledge: Guiding Student Conceptualization through Teacher Embodied Instruction in a Robotics Programming Class

    Science.gov (United States)

    Kwah, Helen

    2013-01-01

    This thesis explores the questions of how a teacher guides students to see concepts, and the role of gesture and gesture viewpoints in mediating the process of guidance. To examine these questions, two sociocultural theoretical frameworks--Radford's cultural-semiotic theory of knowledge objectification (e.g., 2003), and Goldman's Points of Viewing…

  9. Reference: ERELEE4 [PLACE

    Lifescience Database Archive (English)

    Full Text Available ERELEE4 Montgomery J, Goldman S, Deikman J, Margossian L, Fischer RL Identification of an ethylene-re...sponsive region in the promoter of a fruit ripening gene. Proc Natl Acad Sci USA 90:5939-5943 (1993) PubMed: 8327464; ...

  10. Slowing Military Change

    Science.gov (United States)

    2008-10-01

    to Modern Warfare, Oxford: Blackwell , 1988. 14. The following dates may not be agreed to by all, but minor variations of a year or two do not alter...History of Warfare, p. 225. 82. van Creveld, The Changing Face of War, p. 9. 78 83. Ibid., pp. 10-11. 84. Emily Goldman, “The Spread of Western

  11. Cumulative toxicity of an environmentally relevant mixture of nine regulated disinfection by-products in a multigenerational rat reproductive bioassay

    Science.gov (United States)

    CUMULATIVE TOXICITY OF AN ENVIRONMENTALLY RELEVANT MIXTURE OF NINE REGULATED DISINFECTION BY-PRODUCTS IN A MULTIGENERATIONAL RAT REPRODUCTIVE BIOASSAY J E Simmons, GR. Klinefelter, JM Goldman, AB DeAngelo, DS Best, A McDonald, LF Strader, AS Murr, JD Suarez, MH George, ES Hunte...

  12. The Synthesis of Stable Force-Closure Grasps.

    Science.gov (United States)

    1986-07-01

    Research, Vol. 2, No. 2, 1983, pp. 35-45. Featherstone, R. - Robot Dynamics Algorithms" Ph.D. Thesis, Dent of Artificial Intelligence, Univ. of Edinburgh...1984. Featherstone, R. "Spatial Notation: A Tool For Robot Dynamics " D.A.I Research Paper 213, University of Edinburgh, 1984. Goldman. A.J., Tucker, A.W

  13. Kogu maailma hõlmav supertsükkel / Fredy-Edwin Esse

    Index Scriptorium Estoniae

    Esse, Fredy-Edwin

    2011-01-01

    Goldman Sachs Groupi, Pricewaterhouse Coopersi ja London's Standard Chartered Banki makroökonomistid ennustavad majanduskasvu saabumist järgmistel aastakümnetel. Standard Charteredi peaökonomist Gerard Lyons prognoosib majanduse n.-ö. supertsüklit

  14. Mechanisms of Chinese Red Yeast Rice Inhibition of Prostate Cancer Growth

    Science.gov (United States)

    2009-10-01

    Sacks FM, Moye LA, Goldman S, Flaker GC, Braunwald E. Inflammation, pravastatin, and the risk of coronary events after myocardial infarction in...on the development and progression of cancer. Cancer Treat Rev 2004;30:609–641. 53. Muller C, Kiehl MG, van de Loo J, Koch OM : Lovastatin induces

  15. The Four Domains of Moral Education: The Contributions of Dewey, Alexander and Goleman to a Comprehensive Taxonomy.

    Science.gov (United States)

    Zigler, Ronald Lee

    1998-01-01

    Attempts to place a neglected dimension of John Dewey's work into its proper context. Examines the works of Dewey, F. Matthias Alexander, and Daniel Goldman to create four domains that must be addressed by a truly comprehensive model of moral education: direct external, indirect external, direct internal, and indirect internal. (DSK)

  16. Context Building and Educating Imaginative Engagement

    Science.gov (United States)

    Fenner, David E. W.

    2010-01-01

    When audience members consider aesthetic objects and/or works of art, they typically bring to their consideration a number of perspectives through which the object is considered. These include background beliefs, personal associations, taste preferences, and attitudes and values. Using Alan Goldman's aesthetic value theory as a platform, I…

  17. Games for Health, 2011

    Science.gov (United States)

    2011-06-01

    for Families of Returning Veterans Using Emotionally Responsive Avatars Ron Goldman, Kognito, Inc. Games for Shoppers : Brainstorming Play at...Nutrition Education with Online Game Experiences Sally Schmidt & Jori Clarke, Circle1Network Camp Eatapita: A Nutrition Game for Young Kids Steve

  18. Federal Educational Assistance Programs Available to Service Members: Program Features and Recommendations for Improved Delivery

    Science.gov (United States)

    2015-01-01

    thoughtful review improved this research, both in design and execution. We also thank two reviewers, Charles Goldman and Jose Luis xiv Federal...Security Administration xvi Federal Educational Assistance Programs Available to Service Members TA tuition assistance USC U.S. Code VA Department

  19. Genes May Play Role in More Severe Form of PMS

    Science.gov (United States)

    ... white blood cells. They found a complex of genes that acts differently in women with the disorder compared to women without it. Dr. David Goldman, of the U.S. National Institute on Alcohol Abuse and Alcoholism, worked with Schmidt on the study. "This is ...

  20. A Message to Wall Street's Fabulous Fabs

    Institute of Scientific and Technical Information of China (English)

    Michael Lewis

    2010-01-01

    @@ If you happen to be sitting on the Goldman Sachs bond-trading floor, life must feel horribly unfair. You did nothing worse than live by the ethical assumptions of your market-any money-making event short of obviously illegal is admirable--and now your own grandfather thinks you're some kind of monster. Your world feels upside down.

  1. Evidence-Based Counseling Interventions with Children of Divorce: Implications for Elementary School Counselors

    Science.gov (United States)

    Connolly, Marianne E.; Green, Eric J.

    2009-01-01

    Parental divorce has become increasingly common for large numbers of families in schools (Lamden, King, & Goldman, 2002). This article addresses the effects of divorce on children and protective factors supporting their adjustment. Evidence-based interventions for children of divorce in elementary school counseling programs are discussed.…

  2. Are Banks Playing It Too Safe?

    Institute of Scientific and Technical Information of China (English)

    David Henry

    2009-01-01

    @@ Barely a year after Lehman Brothers toppled under the weight of its own debt, Wall Street is calling for some players to load up again. Analysts say Goldman Sachs, Morgan Stanley, JP-Morgan Chase, and other relatively healthy firms are holding too much capital-an overly cautious stance that's costing shareholders billions of dollars in profits.

  3. Alcohol and drug expectancies as anticipated changes in affect: Negative reinforcement is not sedation

    NARCIS (Netherlands)

    Wiers, R.W.H.J.

    2008-01-01

    Goldman and Darkes (2004) argued that all three basic alcohol-expectancy factors can be assessed with a brief questionnaire (AEMax), related to the circumplex model of emotion. I argue that negative reinforcement, one of the three basic expectancy factors, is not assessed with the AEMax. Importantly

  4. Invisible Wounds of War. Summary and Recommendations for Addressing Psychological and Cognitive Injuries

    Science.gov (United States)

    2008-01-01

    advice throughout this project. We thank LTC David Benedek , Howard Goldman, Cathy Sherbourne, LTG Ronald Blanck (Ret.), Thomas Garthwaite, and Carole...www.rand.org/pubs/monographs/MG191/ Hoge, C. W., S. E. Lesikar, R. Guevara, J. Lange , J. F. Brundage, Jr., C. C. Engel, S. C. Messer, and D. T. Orman

  5. The Effects of Rate Controlled Speech on the Listening Comprehension of Learning Disabled and Normal Children.

    Science.gov (United States)

    Teach, Joan K.

    The study explored the differences in the abilities of 20 learning disabled (LD) students (6-8 years old) and 19 normal Ss to perform on listening tasks. In phase I, performance levels were assessed on the Goldman Fristoe Woodcock Test of Auditory Discrimination and a listening comprehension skill battery (the Durrell Listening-Reading Series,…

  6. Examining Speech Sound Acquisition for Children with Cochlear Implants Using the GFTA-2

    Science.gov (United States)

    Flipsen, Peter, Jr.

    2011-01-01

    This study examines use of the Goldman-Fristoe Test of Articulation-Second Edition (GFTA-2) with children who use cochlear implants to evaluate whether or not it would be appropriate to use this test with this population. Participants included 15 children with cochlear implants who ranged in age of implantation and amount of implant experience.…

  7. Applied Epistemology: Prospects and Problems

    DEFF Research Database (Denmark)

    Klausen, Søren Harnow

    2009-01-01

    Artiklen påpeger at anvendt erkendelsesteori er en forbløffende underudviklet disciplin. Alvin Goldmans udkast til en social erkendelsesteori kan på mange måder danne forbillede for anvendt erkendelsesteori, men vises sig alligevel at have alvorlige begrænsninger, som særligt skyldes bestræbelsen...

  8. Hemolytic crisis

    Science.gov (United States)

    ... Hemolysis - acute References Ezenkwele UA. Emergency management of red blood cell disorders. In: Adams JG, ed. Emergency Medicine: Clinical Essentials . 2nd ed. Philadelphia, PA: Elsevier Saunders; 2013:chap 204. Gallagher PG. ... red blood cell membrane and metabolic defects. In: Goldman L, Schafer ...

  9. Paroxysmal cold hemoglobinuria (PCH)

    Science.gov (United States)

    ... Images Blood cells References Jager U, Lechner K. Autoimmune hemolytic anemia. In: Hoffman R, Benz EJ Jr, Silberstein LE, Heslop HE, Weitz JI, Anastasi J, eds. Hematology: Basic Principles and Practice ... M. Autoimmune and intravascular hemolytic anemias. In: Goldman L, Schafer ...

  10. Febrile/cold agglutinins

    Science.gov (United States)

    ... Saunders; 2016:chap 317. Jäger U, Lechner K. Autoimmune hemolytic anemia. In: Hoffman R, Benz EJ Jr, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice . 6th ed. Philadelphia, ... M. Autoimmune and intravascular hemolytic anemias. In: Goldman L, Schafer ...

  11. A Harmonious Quartet

    Institute of Scientific and Technical Information of China (English)

    YAN WEI

    2010-01-01

    @@ When Goldman Sachs first coined the BRIC concept a decade ago, the international investment and securities firm by no means expected that Brazil, Russia, India and China would later unite into a formal alliance. Indeed, if anything, the four fast-growing Economics have since proven that BRIC represents far more than just an eye-catching acronym.

  12. Becoming BRICS

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Adding South Africa to its ranks makes BRICS even more representative of global emerging and developing economies In 2001,Jim O’Neill,Chairman of Goldman Sachs Asset Management,introduced the world to the idea of BRIC countries—Brazil,Russia,India and China,countries that were attracting international attention for

  13. Building With BRICS

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    South Africa’s membership into the BRICS club of emerging nations will bring more opportunities to the whole of Africa WHEN Jim O’neill, then Global economistat Goldman sachs, put forward the idea of BRIC in 2001, he could not have expected that the acronym term he used to describe

  14. Stop snyderiet!

    DEFF Research Database (Denmark)

    Kock, Christian Erik J

    2014-01-01

    Dit job som journalist er at stoppe snyderiet, når politikere ikke svarer – eller svarer udenom. Men det lykkes langtfra altid, for eksempel slap Bjarne Corydon uden om flere af de mest oplagte spørgsmål i sagen om Goldman Sachs. Her er, som en velment guide, nogle værktøjer til journalister...

  15. An Investigation of Three Extremity Armor Systems: Determination of Physiological, Biomechanical, and Physical Performance Effects and Quantification of Body Area Coverage

    Science.gov (United States)

    2012-03-19

    et al., 2002; Sagiv, Ben- Sira , Sagiv, Werber, & Rotstein, 1994; Soule, Pandolf, & Goldman, 1978). Few studies have been done on the energy consumed...37(4), 649-656. Sagiv, M., Ben- Sira , D., Sagiv, A., Werber, G., & Rotstein, A. (1994). Left ventricular responses during prolonged treadmill

  16. A Three-Part Theory of Critical Thinking: Dialogue, Mental Models, and Reliability

    Science.gov (United States)

    2000-08-01

    Goldman, 1992, 1986; Dretske, 1983; Nozick , 1981; Sosa, 1991; Plantinga, 1993). According to one version of externalism, called reliabilism ( Nozick , 1981... Nozick , R. (1981). Philosophical explanations. Cambridge, MA: Harvard University Press. Patel, V. L. & J., G. G. (1991). The general and specific nature

  17. EN TORNO A LA ASIMETRÍA DE LOS GÉNEROS EN LA SOCIEDAD MAPUCHE DEL PERÍODO DE LA CONQUISTA HISPANA

    Directory of Open Access Journals (Sweden)

    FRANCIS GOICOVICH VIDELA

    2003-08-01

    Full Text Available The primacy of masculine gender in almost every domain of culture is an universal phenomenon: men and women participate in differentiated value systems which, according to Marvin Harris, are grounded in the exclusive practice of war by men. The mapuche society in the conquest days was not an exception, and the ideology behind their social practices determined an asymmetry between both genders. centrality of civil legislation for the consolidation of the new order in the continent

  18. The Delphi Method and Its Applications: A Bibliography

    Science.gov (United States)

    1976-06-01

    R. Bright. 2 3 p. Ackerman, James S., On Scieetla., Science and Culture: Gerald Hniton. 9p. Adelson, Marvin, The Technology of Forecasting and the...Science. Science and Culture, Gerald Holton . 41p. Anderson, Alison A. and Anderson, Jay Martin., Systems Simulation to Identify Environmental Research Needs... Gerald Holtons Hanks, Charles, et al, "Alternative Future Patterns Projected with the Field Anomaly Relaxation Method--September 1972&" Menlo Park

  19. A Compilation of Unsteady Turbulent Boundary Layer Experimental Data,

    Science.gov (United States)

    1981-11-01

    HIRSCH KITAet ai, GOSTELOW EHERENSBERGER LU HO & CHEN KOBASHI & HAYAKAWA MAINARDI & PANDAY MARVIN* LORBER & COVERT MIZUSHINA I SAXENA RAMAPRIAN & TU...Laminar Boundary Layer by a Moving Belt. AIAA Paj_2r 69-40, New York, N.Y., 1969. (LT) Mainardi , H. and Panday, P. K.: A Study of Turbulent Pulsating...Flow in a (-cular Pipe. Eurovisc 77 - Unsteady Turbulent Boundary Layers and Shear Flows, Toulouse, France, Jar,. 2977. (TE-D) Mainardi , H. and Panday

  20. Diversity and Black Officer Integration in the U.S. Marine Corps for 2011 and Beyond

    Science.gov (United States)

    2011-05-06

    Press, 1986. Shaw , Jr., Henry I., and Ralph W. Dmmelly. Blacks in the Marine Corps. History and Museums Division, Headquarters Marine Corps...fightingforrespect.aspx Binkin, Martin, Mark J. Eitelberg, Alvin J. Schexnider, and Marvin M. Smith. Blacks and the Military: Studies in Defense Policy...192. 7 Henry I. Shaw , Jr. and Ralph W. Donnelly, Blacks in the Marine Corps (History and Museums Division, Headquarters Marine Corps, Washington

  1. Rearming for the Cold War, 1945-1960 (History of Acquisition in the Department of Defense. Volume 1)

    Science.gov (United States)

    2012-01-01

    Navy Medical Purchasing Office (for medicines and other medical supplies) and the Armed Services Petroleum Purchasing Agency operated in this way...Charles C. Lauritsen of Caltech. 112. Thomas P. Hughes, Rescuing Prometheus , 23-27. 113. J. R. Marvin and F. J. Weyl, "The Summer Study," Naval Research... Prometheus , 24-26 114. Memo, William A. Fowler for Group Chairmen, 5 February 1952, sub: Scientific Effort Required for Project Vista, folder

  2. Using Parallel Processing for Problem Solving.

    Science.gov (United States)

    1979-12-01

    his support, keen interest, and hyperopic view of the computer field. Jerry Barber, Randy Davis, Roger Duffey, Ken Forbus, David Levitt, and Luc...Harold Goldberger, Ken Kahn, Bob Kems, Henry Lieberman, Marvin Minsky, Vaughn Pratt, Maria Simi, Barbara Steele, Richard Stallman, and Sten-Ake Tamlund...Reference Manual, School of Artificial Intelligence, University of Edinburgh, TPU Report no. 1, May 1973. [251 Wilber , Michael B., A QLISP Reference

  3. The UIR Framework: An Approach to Developing Culturally Savvy Logisticians

    Science.gov (United States)

    2008-03-25

    LOGISTICIANS by Colonel Marvin S. Whitaker United States Army Dr. Richard Meinhart Project Adviser This SRP is...WHITAKER United States Army DISTRIBUTION STATEMENT A: Approved for Public Release. Distribution is Unlimited. USAWC CLASS OF 2008 This SRP is...paper are those of the author and do not reflect the official policy or position of the Department of the Army , Department of Defense, or the U.S

  4. Independent Panel Evaluation of Dry Sludge PISA Program

    Energy Technology Data Exchange (ETDEWEB)

    Fondeur, F.F.

    1999-10-20

    Dr. Kirk Yeager and Mr. Marvin Banks from Energetic Material Research and Technology Center (EMRTC) evaluated the Savannah River Site (SRS) efforts in the Dry Sludge program. They evaluated four program areas: energetic material formation, stability, initiation, and propagation. The panel evaluation included a site visit (July 13, 1999 and July 14, 1999) as well as a review of various reports and presentations by researchers involved in the program.

  5. Maritime Threat Response

    Science.gov (United States)

    2006-06-01

    139 S. Fetter, V.A. Frolov, M. Miller, R. Mozley, O.F. Prilutsky, S.N. Rodionov, and Roald Z. Sagdeevb...difficulties refer to Steve Fetter, Valery A. Frolov, Marvin Miller, Robert Mozley, Oleg F. Prilutsky , Stanislav N. Rodionov, and Roald Z. Sagdeevb...and Port Security, Chelsea House Publishers, 2004. Fabris, L., Madden, N., Nikolic, R.W., Swanson, J., Wang , T., McGregor, D., and Cheung, B

  6. [Classification and staging systems for hilar cholangio-carcinoma (Klatskin tumors): clinical application and practical relevance].

    Science.gov (United States)

    Gavrilovici, V; Grecu, F; Seripcariu, V; Dragomir, Cr

    2011-01-01

    Hilar cholangiocarcinomas or Klatskin tumors have been classified in 1975 by French surgeons Henri Bismuth and Marvin B. Corlette and this remains largely used in clinical practice. The authors present the TNM classification and the changes introduced by the sixth and seventh edition of Union for International Cancer Control regarding the tumors of the proximal bile duct and describe Blumgart classification for tumors of this site. The usefulness of these systems is assessed considering the last six years experience of the service.

  7. Integrating Images, Applications, and Communications Networks. Volume 5.

    Science.gov (United States)

    1987-12-01

    important in developing a keen understanding of expert systems and the reasoning necessary for determining the success of a system. The first, and...assigned to them. Each image can be characterized by the concept of frames. Originally proposed by Marvin Minsky in [21), this scheme decomposes knowledge...Scanning, Part I. Brit. J. Radiology 46:1016-1022, [17] Gary Kahn, Steve Nowlan, and John McDermott. , A Foundation for Knowledge Acquisition. IEEE

  8. Feature Extraction and Classification of FLIR Imagery Using Relative Locations of Non-Homogeneous Regions with Feedforward Neural Networks

    Science.gov (United States)

    1992-04-01

    and encouragement. In addition, I wish to thank my advisor Dr Steve Rogers (aka Captain Amerika) who has been patient when I was frustrated and when I...the organization of the dissertation. 1.2 Motivation The problem of target identification from FLIR, ladar or radar information has been of keen ...Company, 2nd edition, 1970. 33. Marvin L. Minsky and Seymour A. Papert. Percepirons - Expanded Edition. MIT Press, 1988. 34. Frederick C. Mish, editor

  9. A History of the Waterways Experiment Station 1929-1979

    Science.gov (United States)

    1979-06-01

    Matthews, Margaret S. McNeal, Linda S. Liggins, Edward L. Mattingly, Betty P. McPhearson, James A. Lindley, Oscar E. Maxey, John L. McVay, Mark K...Lloyd, Cheryl M. May, J ohn R. Meyer, Marvin P. Lloyd, Michael K. Mayfield, James, Jr. Miller, Charles A. Lockard, Susan Mayfield , Oscar , Jr...D. Sherlock, Ann R. Smith, Patricia A. Rubin de Ia Borbolla , GeorgeS. Sherlock, James A. Smith, Perry A. Rush, Edgar S. Sherman, Walter C., Jr

  10. 新闻人物

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    陈竺:新上任卫生部部长;RitaColwell:获得美国国家科技奖;MarvinCaruthers:因发明单链DNA合成法获得美国国家科技奖;Lubert Stryer:因发明细胞荧光技术获得美国国家科技奖

  11. Reorganizing U.S. Domestic Intelligence: Assessing the Options

    Science.gov (United States)

    2008-01-01

    Americans have been killed by lightning than by terrorism since September 11,1 the scale of the September 11 attacks was unprecedented 1 In 2005, for...instance, the numbers were 56 for terrorism versus an average of 62 per year for lightning over the previous five years. See U.S. Department of State...Calif.: RAND Corporation, WR-487- IEC , 2007. As of May 14, 2008: http://www.rand.org/pubs/working_papers/WR487/ Lavin, Marvin, Intelligence

  12. American River Watershed Project, California. Part 1: Main Report. Part 2: Final Supplemental Environmental Impact Statement/Environmental Impact Report. Supplemental Information Report

    Science.gov (United States)

    1996-03-01

    planned to increase the supply. The Coastal Branch Aqueduct is currently under construction and will serve San Luis Obispo and Santa Barbara Counties...the Rincon -Marvin- Tehama association, Sycamore-Tyndall association, and Capay-Sacramento association. These diverse soils support irrigated orchards...deliveries. "* CVP south of Delta deliveries. "* CVP storage in Clair Engle, Shasta, and Whiskeytown Reservoirs and the CVP share of San Luis

  13. The Military Decision Making Process: Making Better Decisions Versus Making Decisions Better

    Science.gov (United States)

    2007-11-02

    Mind, ed. Suresh Srivastva, (San Francisco: Jossey- Bass Publishers), 1983 and Herbert A. Simon, Administrative Behavior, 3d edition, (New York: The...Marvin Thordsen, Joseph Glushka, Gary Klein, Saul Young, and Christopher Brezovic. “A Knowledge Elicitation Study of Military Planning,” Technical...Edited by Suresh Srivastva. San Francisco: Jossey- Bass Publishers, 1983. 70 Kolb, David A. and Donna M. Smith. User’s Guide for the Learning Style

  14. Minimally invasive aesthetic procedures in young adults

    Directory of Open Access Journals (Sweden)

    Wollina U

    2011-03-01

    Full Text Available Uwe Wollina1, Alberto Goldman21Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, Germany; 2Clinica Goldman, Porto Alegre, Rio Grande du Sul, BrazilAbstract: Age is a significant factor in modifying specific needs when it comes to medical aesthetic procedures. In this review we will focus on young adults in their third decade of life and review minimally invasive aesthetic procedures other than cosmetics and cosmeceuticals. Correction of asymmetries, correction after body modifying procedures, and facial sculpturing are important issues for young adults. The implication of aesthetic medicine as part of preventive medicine is a major ethical challenge that differentiates aesthetic medicine from fashion.Keywords: acne scars, ice pick scars, boxcar scars, fillers 

  15. Experimental constraints on anti-gravity and antimatter, in the context of dark energy

    CERN Document Server

    Ting, Yuan-Sen

    2013-01-01

    In a paper by Villata (2011), the possibility of a repulsive gravitational interaction between antimatter and ordinary matter was discussed. The author argued that this anti-gravity can be regarded as a prediction of general relativity, under the assumption of CPT symmetry. Stringent experimental constraints have been established against such a suggestion. The measurement of free-fall accelerations of various nuclei by the Eot-Wash group and searches for equivalence principle violation through the gravitational splitting in kaon physics consistently establish null results on any difference between the gravitational behaviour of antimatter and ordinary matter. The original arguments against antigravity were questioned by Nieto & Goldman (1991). In the light of new experiments as well as theoretical developments in the past 20 years, some of Nieto & Goldman's concerns have been addressed. While a precise measurement of the free-fall acceleration of antihydrogen will eventually lay this issue to rest, th...

  16. [Diffusion and diffusion-osmosis models of the charged macromolecule transfer in barriers of biosystems].

    Science.gov (United States)

    Varakin, A I; Mazur, V V; Arkhipova, N V; Serianov, Iu V

    2009-01-01

    Mathematical models of the transfer of charged macromolecules have been constructed on the basis of the classical equations of electromigration diffusion of Helmholtz-Smolukhovskii, Goldman, and Goldman-Hodgkin-Katz. It was shown that ion transfer in placental (mimicking lipid-protein barriers) and muscle barriers occurs by different mechanisms. In placental barriers, the electromigration diffusion occurs along lipid-protein channels formed due to the conformational deformation of phospholipid and protein molecules with the coefficients of diffusion D = (2.6-3.6) x 10(-8) cm2/s. The transfer in muscle barriers is due to the migration across charged interfibrillar channels with the negative diffusion activation energy, which is explained by changes in the structure of muscle fibers and expenditures of thermal energy for the extrusion of Cl- from channel walls with the diffusion coefficient D = (6.0-10.0) x 10(-6) cm2/s.

  17. Fiscal Fetters: The Economic Imperatives of National Security in a Time of Austerity

    Science.gov (United States)

    2012-01-01

    strategic transformation of its military played to US strengths in capital- intensive warfare and technological innovation while pivoting away from the...implications of economic change for the large, populous developing economies. Re­ searchers for the investment bank Goldman Sachs coined the term BRIC ...Perspectives on Global Development: Shifting Wealth (Paris: OECD, 2010), 15. 52. Dominic Wilson and Roopa Purushothaman, Dreaming with BRICs : The Path to

  18. Grecia, cronaca di un disastro annunciato

    OpenAIRE

    Gabellini, Giacomo

    2016-01-01

    L’origine della crisi greca risale al 2009, quando vennero a galla i dati autentici riguardo allo stato reale in cui versava l’economia nazionale. Per nascondere i dati reali, i dirigenti greci ricorsero all’assistenza delle banche d’investimento Goldman Sachs e Jp Morgan Chase falsificando i conti e permettendo al paese di aderire alla "zona euro". Con l'ascesa del partito socialista PASOK, il vero stato delle finanze pubbliche è stato reso noto ai lor...

  19. An Agent for the Prospect Presentation Problem

    Science.gov (United States)

    2014-05-01

    example is a medical system which assists a doc- tor or patient in deciding whether to use a certain medica - tion. The medication is associated with one...affects the users’ interaction with the agent. We chose the pie charts (combined and separate) in order to enhance com- prehension of the proposed...Z. Rabinovich, S. Kraus, C. V. Goldman, and Y. Gal. Strategic advice provision in repeated human-agent interactions . In AAAI, 2012. [5] A. Azaria, Z

  20. An Overview of the Role of the Unit Ministry Team (UMT) in Operation Desert/Shield/Desert Storm with a Critical Evaluation of Religious Support Activities and Technical Doctrine, and Command Team Assessment of UMT Actions, Capabilities and Effectiveness

    Science.gov (United States)

    1992-04-03

    for industrial chaplaincies, perform ministry in a unique institution. Sociologist Erving Goffman called this unique social structure a "Total...20. 9. Richard G. Hutcheson Jr., The Churches and the Chaplaincy, p. 17. 10. Erving Goffman , Asylums, p. 15. 11. Chaplain Corps Mini-FAA...1980. Goffman , Erving . Asylums. Garden City, New York: Doubleday and Company, Anchor Books, 1961. Goldman, Nancy L. "Trends in Family Patterns of

  1. U.S. Army Biomedical Research and Development Laboratory Bibliography FY91-FY80 (Reverse Order). Appendix

    Science.gov (United States)

    1991-01-01

    J.H. Nelson, and D.L. Danley. 1991. Pulsed, non-thermal, high frequency electromagnetic energy (diapulse) in the treatment of grades I and II ankle... wave locator for radiotransparent foreign bodies. Final report, phase I, DAMD17-91-C-1016. Newton Center, MA: Geo-Center, Incorporated. UBLJCAIONi...Research. Kawakami, T.G., N. Cone, J.D. Henderson, L.S. Rosenblatt, N. Goldman, J.C. Dacre, and B.W. Wilson. 1990. Genotoxicity of the

  2. Receptor Tyrosine Kinases as Targets for Treatment of Peripheral Nerve Sheath Tumors in NF 1 Patients

    Science.gov (United States)

    2010-03-01

    tonsil tissue. Negative control stainings without pri- mary antibodies did not produce signals. For immunocytochemistry, Schwann cells were grown on...Silver RT, Goldman JM, Stone RM et al (2006) Five-year follow-up of patients receiving i- matinib for chronic myeloid leukemia. N Engl J Med 355(23...30, namely no further growth of their tumors. It is our hope that this work will set the stage, a mile- stone for much more sophisticated and

  3. Üleilmse finantskriisi leevenemist silmapiiril veel ei paista / Erik Aru

    Index Scriptorium Estoniae

    Aru, Erik

    2007-01-01

    Maailma rahaturgudel kestab veel krediidikriis. Mitme vaatleja hinnangul näitab see, et kriis pole lahenenud ka pärast intressimäära langetamist, et tegemist on tõsise probleemiga. Investeerimispanga Goldman Sachs peaökonomist Jan Hatzius soovitab intressi veelgi vähendada. Hinnanguid kahjumi suuruse kohta. Lisad: Pangandus - pidev kriiside allikas; Euroopa keskpankureid inflatsioon ei loksuta

  4. Basic Research in Artificial Intelligence and Foundations of Programming

    Science.gov (United States)

    1980-05-01

    Rover, Proc. 6th Int. Joint Conf. on Artiftial Intelligence, Tokyo, Japan, August 98. McCarthy, John. Ascribing Mental 1979, pp. 589-601. Qualities to...Semantics, Comunicaciones Tecnicas (in Spanish). Blue Series: monographs. Center 1 17. Nevatia, R., T.O. Binford; Structured for Research in Applied...Ron Goldman, AL Users’ Manual. + AIM-326 CS-725 136 pages, January 1979. Cost: 15.50 McCarthy, John, Ascribing Mental Qualities to Machines. This

  5. Attention - Control in the Frequentistic Processing of Multidimensional Event Streams.

    Science.gov (United States)

    1980-07-01

    at the time of encoding has been found to affect recall (e. g. Eysenck & Eysenck , 1979) and the magnitude of subsequent FES (e. g. Goldman...Pellegrino, 1977; Rowe, 1974). Eysenck and Eysenck (1979) have equated depth of processing with the extent to which semantic content and "meaningfulness" are...generally semantic vs. non-semantic) involved in encoding determines the like- lihood that the stimulus will be retrieved subsequently ( Eysenck & Eysench

  6. RMB Interest Rates Will Continue to Rise

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    Lehman Brothers say that the recent 0.27 percentage point rise in RMB interest rates is just for starters, and that China will continue to higher RMB interest rates, They forecast a rise up to 6 percent on a oneyear loan by the end of 2005. Liang Hong,chief economist at the Goldman Sachs investment bank, says that although the rise in RMB interest rates may be minimal,

  7. Probabilistic Plan Management

    Science.gov (United States)

    2009-11-17

    Bryan Horling, John Phelps, Robert Goldman, Regis Vincent , C. Long, and Bob Kohout. C TAEMS language specification v. 1.06. October 2005. 3.3.2 Justin A...International Conference on Automated Planning and Scheduling (ICAPS ’05), Monterey, California, 2005. 2.2.2, 8.1.4 Vincent Vidal and Héctor Geffner...spec_task (label squashbug-syncpoint) (subtasks cloudscape salesman plainsman angina ) (qaf q_sync_sum)) (spec_task (label cloudscape) (subtasks orient

  8. U.S.Economy:A Pessimistic View

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Worse than expected economic data is igniting fears of a serious U.S.economic retrenchment-economic growth in the United States was down to 1.6 percent in the second quarter,despite the 3.7 percent rate in the first quarter of 2010.Qiao Hong,chief economist at Goldman Sachs China,forecasted a gloomy outlook for the U.S. economy but said a "double-dip" recession is unlikely.

  9. Malignants In The Body Politic: Redefining War Through Metaphor

    Science.gov (United States)

    2002-06-01

    Patrick Davis, “Normal Flora,” in Medical Microbiology , 4th 11 Microbes do breach these barriers (through wounds, for instance), but the cells of...Normal Flora.” In Medical Microbiology , 4th ed. Edited by Samuel Baron. Galveston, TX: University of Texas Medical Branch, 1996. Druker, Brian J...Nature, 17 August 2000, 799–803. Goldman, Armond S., and Bellur S. Prabhakar. “Immunology.” In Medical Microbiology , 4th ed. Edited by Samuel Baron

  10. Military Nutrition Research.

    Science.gov (United States)

    1983-10-01

    Torranin, C. 1979. Effect of acute thermal dehydration and rapid rehydration on isometric and isotonic endurance. J. Sports Med. 19:1-9. Wickens, C. D...might be perceived by themselves and others as being at some disadvantage , and the lIRE ration could even be used as an excuse for poor performance...for rehydrating food but also for drinking . BIBLIOGRAPHY ON WATER UTILIZATION Beisel, W. R., R. F. Goldman, and R. J. T. Joy. 1968. Metabolic balance

  11. Limnology of Priyadarshani Lake, Schirmacher Oasis, Antarctica

    Digital Repository Service at National Institute of Oceanography (India)

    Ingole, B.S.; Parulekar, A.H.

    in Schinnacher Oasis (Antarctica), was surveyed during the austral summers of 1984-85 and 1986-87 in limnological and benthic studies. Benthic microfaWla included seven taxonomic groups, dominated numerically by protozoa, rotifera, nematoda, turbellaria... insulation during the harsh winter (Goldman and others 1972). Seven microfaunal groupswer~recorded, in which ten genera and four species were identified. Most ofthese are exclusively benthic animals ofboth peripheral and littoral zones. Protozoa (ciliata...

  12. NASA Day at the Capitol

    Science.gov (United States)

    2009-01-01

    Astronaut Rex Walheim (center) speaks to members of the Mississippi House of Representatives in chambers during NASA Day at the Capitol in Jackson on Feb. 19. Walheim was joined at the podium by members of the Mississippi House of Representatives Gulf Coast delegation, as well as Stennis Space Center Director Gene Goldman (astronaut's immediate right) and NASA's Shared Services Center Director Rick Arbuthnot and Partners for Stennis Executive Director Tish Williams (astronaut's immediate left).

  13. Pure Perseverance: A Study of Women's Small Businesses in Colombia: Understanding Success Factors of Women's and Men's Small Businesses in Bucaramanga, Colombia

    OpenAIRE

    Jennifer Powers; Barbara Magnoni

    2013-01-01

    Supporting women's businesses has become a topic of growing interest to governments and mainstream development institutions in recent years. Declarations to address women's unequal access to economic opportunity at the G-20 Summit, the development of UN Women, and the Goldman Sachs 10,000 Women Initiative reflect that mainstream institutions are adopting a role in improving women's economic opportunities throughout the developed and developing world. This study aims to inform thinking around ...

  14. Long Cycle Life Secondary Lithium Cells Utilizing Tetrahydrofuran.

    Science.gov (United States)

    1984-04-01

    2Me-THF (see Table 2 for structural formulas). In fact, most of the published * Electrochemical Society Active Member Key wordos Li Battery...the Electrochemical Society , Washington, D. C. (1983). Abstract No. 58. 12. K. N. Abraham, 3. L. Goldman, P. B. Harris, 3. Avery and S. B. Brummer...Fall Meeting of the Electrochemical Society , Detroit, MI (1982), Extended Abstract No. 314. 6 % .% < a- . _. -w CT -N T .77 -~ FIGURE CAPTION Figure 1

  15. Thermal Decomposition of Dimethoxymethane Electrolyte Solution.

    Science.gov (United States)

    1982-06-01

    DIMETHOXYMETHANE ELECTROLYTE SOLUTION by J. S. Foos and V. Meltz Prepared for Publication in the Journal of the Electrochemical Society EIC...Journal of the Electrochemical Society . III. KEY WORDS (Conitiue onl reverse side It neci’eay and Identify by block nsinibor) Lithium Battery, Organic...Batteries, B. B. Owens and N. Margalit, eds., Vol. 80-4, The Electrochemical Society , Pennington, NJ, 384 (1980). .2. K. M. Abraham, J. L. Goldman and D. L

  16. BEAUTY IN THE AGE OF MARKETING

    OpenAIRE

    Bingqing Yin; Susie Pryor

    2012-01-01

    Research has repeatedly demonstrated that beauty is positively related to a number of important outcomes including social and personal power, self-esteem, and preferential treatment from others (Bloch and Richins, 1992; cf. Adams, 1977; Goldman and Lewis, 1977). Moreover, studies consistently suggest that the use of physically attractive models results in positive effects (Berscheid and Walster, 1974; Bower, 2011; Buunk and Dijkstra, 2011; Landy and Sigall, 1974). Accordingly, advertisers uti...

  17. Assessing Dimensionality of a Set of Items - Comparison of Different Approaches

    Science.gov (United States)

    1992-08-10

    Paychologe Progam for Measurement Box 40 Tulan University University of Iowa X,%to’.n. PA 19400040 Ne Orleans, LA 70118 Iowa Cty. IA 52242 Dr. Williamn 0...University Dr. Osisneh Dodand Eshstios Fairfax, VA 2203 Educaional Testng Service Snoai Bldg. Ras. 123OP Princeton. NJ 06541 Uniiesity of Marylandl Dr...Haia 3199 Educationall Test Serviice Pittsburght. PA 15260 ISRAEL PrInceton NJ 08341 Dr. Susan R. Goldman Dr. Gregoty Candel11 Dr. Pik Drasgow, Peabody

  18. Development of Mammalian Cell Lines with lac Operator-Tagged Chromosomes

    OpenAIRE

    sprotocols

    2014-01-01

    Authors: Yuri G. Strukov and Andrew S. Belmont This protocol was adapted from “Development of Mammalian Cell Lines with lac Operator-Tagged Chromosomes,” Chapter 25, in[ *Live Cell Imaging* ](http://www.cshlpress.com/link/livecelp.htm)(eds. Goldman and Spector). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, USA, 2005. ### INTRODUCTION The discovery and use of fluorescent proteins to label chromosomal proteins has yielded basic structural information as well as insig...

  19. Politics and Economics in Putins Russia

    Science.gov (United States)

    2013-12-01

    the 2008 economic crisis than did the other BRIC countries (Brazil, India, and China). Since foreign di- rect investment (FDI) in Russia is a fraction...of the total for the other BRIC members, 4.1 percent for 2007, that pace of recovery will probably not change anytime soon. Reportedly about 20...another, and to the Russian elite, far more palatable frame of reference: the BRICs . Introduced by Goldman Sachs analyst Jim O’Neill in 2001, this

  20. BRICS Power

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    When Goldman Sachs economist Jim O’Neill coined the acronym BRIC to describe collectively Brazil,Russia,India and China,the world mainly regarded it as one of the easy-come,easy-go terms in economics.A decade later,O’Neill’s concept is not forgotten.It is successfully playing an historic role in representing the shift in global economic power away

  1. A Linked Series of Laboratory Exercises in Molecular Biology Utilizing Bioinformatics and GFP

    Science.gov (United States)

    Medin, Carey L.; Nolin, Katie L.

    2011-01-01

    Molecular biologists commonly use bioinformatics to map and analyze DNA and protein sequences and to align different DNA and protein sequences for comparison. Additionally, biologists can create and view 3D models of protein structures to further understand intramolecular interactions. The primary goal of this 10-week laboratory was to introduce…

  2. Misconceptions of Synthetic Biology: Lessons from an Interdisciplinary Summer School

    DEFF Research Database (Denmark)

    Verseux, Cyprien; G Acevedo-Rocha, Carlos; Chizzolini, Fabio;

    2016-01-01

    In 2014, an international group of scholars from various fields analysed the "societal dimensions" of synthetic biology in an interdisciplinary summer school. Here, we report and discuss the biologists' observations on the general perception of synthetic biology by non-biologists who took part in...

  3. Theories of Population Variation in Genes and Genomes

    DEFF Research Database (Denmark)

    Christiansen, Freddy

    as biologists, molecular biologists, breeders, biomathematicians, and biostatisticians. •    Up-to-date treatment of key areas in classical and modern theoretical population genetics •    In-depth coverage of coalescent theory •    Timely discussion of genomic effects of selection •    Inspired by...

  4. From Princesa to Princess with a Prince: 1994 and 2001 Fernanda's Stories

    Directory of Open Access Journals (Sweden)

    Polina Shvanyukova

    2012-12-01

    Full Text Available In an analysis of what presents itself as a cinematic transposition of a literary text, it is difficult to break away from the “binary oppositions [...] literature versus cinema, high culture versus mass culture, original versus copy" (James Naremore. In the case of Princesa (2001, directed by Henrique Goldman, it is questionable whether we can speak about an adaptation at all. As Goldman himself stated, he got the idea for making the film after reading the eponymous 1994 book written by Fernanda Farias de Albuquerque in collaboration with Maurizio Jannelli. In his film, Goldman has made drastic changes to the autobiographical story of Fernanda, the Brazilian transsexual prostitute who travels to Europe in order to earn money for her sex-change operation. However, the film was in fact dedicated to the memory of the real Fernanda, who had passed away in the meantime. In this contribution, the two works will be examined in their relationship to a third source-text by paying special attention to the processes of worldmaking as developed in Nelson Goodman's seminal 1978 book and expanded in the 2010 collection of essays Cultural Ways of Worldmaking. Media and Narratives.

  5. A computer-based microarray experiment design-system for gene-regulation pathway discovery.

    Science.gov (United States)

    Yoo, Changwon; Cooper, Gregory F

    2003-01-01

    This paper reports the methods and evaluation of a computer-based system that recommends microarray experimental design for biologists - causal discovery in Gene Expression data using Expected Value of Experimentation (GEEVE). The GEEVE system uses causal Bayesian networks and generates a decision tree for recommendations. To evaluate the GEEVE system, we first built an expression simulation model based on a gene regulation model assessed by an expert biologist. Using the simulation model, we conducted a controlled study that involved 10 biologists, some of whom used GEEVE and some of whom did not. The results show that biologists who used GEEVE reached correct causal assessments about gene regulation more often than did those biologists who did not use GEEVE.

  6. Burn Wound Healing and Treatment: Review and Advancements

    Science.gov (United States)

    2015-06-12

    creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly...graftin in lethal burns. Plast Reconstruct Surg Transplant Bull . 1962;30:595–9. 54. Engrav LH, Heimbach DM, Reus JL, Harnar TJ, Marvin JA. Early excision...plasma and Rowan et al. Critical Care (2015) 19:243 Page 11 of 12 wound exudate from children with severe burns. Bull Exp Biol Med. 2009;148:771–5. 163

  7. Multifunction peripherals for PCs technology, troubleshooting and repair

    CERN Document Server

    Hobbs, Marvin

    2000-01-01

    Multifunction devices combine the essentials of a fax machine, printer, scanner, and copier into one peripheral for small and home offices. As the market for this equipment grows, the need for skilled repair and maintenance increases. Unfortunately the service documentation supplied by the manufacturers is completely inadequate making the repair jobs even harder and more expensive. Marvin Hobbs teaches you how multifunction peripherals work in theory and in practice with lots of hands-on examples and important troubleshooting and repair tips you don't want to miss.This book fills a gap

  8. Standard/Handbook for Multipactor Breakdown Prevention in Spacecraft Components

    Science.gov (United States)

    2014-05-28

    Tracy Fiedler tracy.m.fiedler@raytheon.co m Raytheon Brad Fields fields.brad@orbital.com Orbital Sherri Fike sfike@ball.com Ball Richard Fink...Rocket Michael Sampson michael.j.sampson@nasa.gov NASA Victor Sank victor.j.sank@nasa.gov NASA Don Sawyer don.sawyer@avnet.com AVNET Fred Schipp...Grumman Ghislain Turgeon ghislain.turgeon@sslmda.co m SSL Deborah Valley deborah.valley@ll.mit.edu MIT Fred Van Milligen fvanmilligen@jdsu.com JDSU Marvin

  9. Meteorites

    Science.gov (United States)

    Zanda, Brigitte; Rotaru, Monica; Hewins, Translated by Roger

    2001-07-01

    1. The harder they fall C. Perron; 2. Stones fallen from the sky U. Marvin; 3. Impact craters P. Thomas; 4. Cretaceous Park R. Rocchia, E. Robin and H. Leroux; 5. Like no rock on Earth B. Zanda, M. Christophe Michel Lévy, M. Bourot Denise and C. Caillet Komorowski; 6. Little planets D. Benest; 7. The Sound and the Fury J.-P. Bibring; 8. Signed carbon F. Robert, M. Festou and F. Raulin; 9. A stormy nebula R. Hewins; 10. The age of the solar system G. Manhès; 11. Galactic fossils E. Zinner; 12. Leafing through the past two centuries... P. Pellas; Glossary; Acknowledgements; Illustration credits.

  10. LC/MS and SFC/MS: will they replace GC/MS

    Energy Technology Data Exchange (ETDEWEB)

    Warner, M.

    1987-07-01

    Will LC/MS and SFC/MS eventually replace GC/MS as the method of choice for organic trace analysis. This question was addressed at a symposium organized by Richard Browner of the Georgia Institute of Technology at this year's Pittsburgh Conference in Atlantic City, NJ. The symposium, one of the best-attended technical sessions at this year's meeting, featured presentations by Browner, Ron Hites of Indiana University, Jack Henion of Cornell University, Dick Smith of Battelle's Pacific Northwest Laboratory, and Marvin Vestal of The University of Houston.

  11. War and National Renewal: Civil Religion and Blood Sacrifice in American Culture

    Directory of Open Access Journals (Sweden)

    Agnieszka Soltysik Monnet

    2012-04-01

    Full Text Available Wars are often associated with a rhetoric of renewal or new beginnings. This essay explores this claim through the lens of civil religion and a recent book by Carolyn Marvin and David Ingle, Blood Sacrifice and the Nation, which combines Emile Durkheim with Réné Girard in proposing that modern national cohesion depends on blood sacrifice. I unpack some of the paradoxes raised by this theory of national renewal in the context of 9/11, with a special focus on the sacred status of the flag and the special attention given to uniformed serviceman in the American body politic

  12. A Wasteland of Love:An Existentialist Approach to The Ballad of the Sad Café

    Institute of Scientific and Technical Information of China (English)

    WANG Ping

    2015-01-01

    The Ballad of the Sad Café is one of McCullers’masterpieces. By depicting the triangle love story among the main char⁃acters—Miss Amelia, hunchbacked Cousin Lymon and Marvin Macy, the novella reveals the incredible complexity of human na⁃ture. By analyzing the absurd town, Miss Amelia’s free choices and the hellish relationship between its main characters from the Existentialist perspective, the main propositions of Existentialism have also been vividly reflected and also help to reveal the philo⁃sophical and social realistic significances behind the novella.

  13. La Utopía de Turing: entre la imaginación y la cibercultura

    OpenAIRE

    von Mayer Chaves, Peggy

    2007-01-01

    Este artículo analiza la novela de ciencia ficción "dura" La Utopía de Turing ("The Turing Option"), del científico estadounidense Dr. Marvin Minsky, máxima autoridad en inteligencia artificial, y de Harry Harrison, renombrado escritor inglés de ciencia-ficción. La novela aborda importantes logros de la ciberciencia de finales del siglo XX, como la robótica, la inteligencia artificial, la nanotecnología aplicada a la medicina, etc. La trama policíaca conduce a cuestionar el espionaje científi...

  14. Alternative Methods and Procedures for the Management of Financial Information to Naval Activities.

    Science.gov (United States)

    1981-11-01

    Ronald J. Golden, NCF Project Director Mr. Robert N. Strain, NAFC-124 Ms. Joanne C. Dula, NAFC-132 Mr. Lisle C. Updike , NAFC-23 Mr. Marvin P. Balding...and recommended direct contact with the Center. Contact was made by telephone by EG&G with Mr. John W. Cooley, Deputy Director of the Army Finance...1. MR. JOHN P. ALBERT NAFC 2. * MR. R. F. ALLEN CNET 3. LT NICK ANDERSON NAFC 4. MS. MARY ANSON NCB-3/OP923 5. * MS. BETTY ATKINSON COMNAVAIRPAC 6

  15. Biological confocal microscopy

    Directory of Open Access Journals (Sweden)

    Guy Cox

    2002-04-01

    Full Text Available The first practical use of confocal optics was by Hiroto Naora1,1,2, who built a device based upon a theoretical concept devised by his supervisor Z. Koana3, over 50 years ago. His system did not form images, but was used in high resolution micro-spectrophotometry. Some 10 years later, Marvin Minsky4 added a scanning stage to construct a microscope capable of forming images. Despite these early advances, in was not until the 1970s that reasonably practical confocal microscopes were built, and the mid 1980s before commercial models became generally available.

  16. Transport, space and society in Copenhagen and Bogotá, 1940-2010

    DEFF Research Database (Denmark)

    Pineda, Andres Felipe Valderrama

    This paper explores the way urban space, transportation networks and urban societies co-evolve and shape each other in time and how this process impacts the development of specific infrastructure projects in cities. To illustrate and analyse these processes, I examine the space design and transport...... the works of Thomas Bender (urban history), John Law (on ANT and post-ANT), Bruno Latour (mainly Reassembling the Social), John Urry (specially his work on mobilities and also his papers on the sociology of automobility), Nigel Thrift (on space), Steven Graham and Simon Marvin (mainly Splintering Urbanism...

  17. The philosophy of modelling or does the philosophy of biology have any use?

    Science.gov (United States)

    Orzack, Steven Hecht

    2012-01-19

    Biologists in search of answers to real-world issues such as the ecological consequences of global warming, the design of species' conservation plans, understanding landscape dynamics and understanding gene expression make decisions constantly that are based on a 'philosophical' stance as to how to create and test explanations of an observed phenomenon. For better or for worse, some kind of philosophy is an integral part of the doing of biology. Given this, it is more important than ever to undertake a practical assessment of what philosophy does mean and should mean to biologists. Here, I address three questions: should biologists pay any attention to 'philosophy'; should biologists pay any attention to 'philosophy of biology'; and should biologists pay any attention to the philosophy of biology literature on modelling? I describe why the last question is easily answered affirmatively, with the proviso that the practical benefits to be gained by biologists from this literature will be directly proportional to the extent to which biologists understand 'philosophy' to be a part of biology, not apart from biology.

  18. Questions for assessing higher-order cognitive skills: it's not just Bloom's.

    Science.gov (United States)

    Lemons, Paula P; Lemons, J Derrick

    2013-01-01

    We present an exploratory study of biologists' ideas about higher-order cognition questions. We documented the conversations of biologists who were writing and reviewing a set of higher-order cognition questions. Using a qualitative approach, we identified the themes of these conversations. Biologists in our study used Bloom's Taxonomy to logically analyze questions. However, biologists were also concerned with question difficulty, the length of time required for students to address questions, and students' experience with questions. Finally, some biologists demonstrated an assumption that questions should have one correct answer, not multiple reasonable solutions; this assumption undermined their comfort with some higher-order cognition questions. We generated a framework for further research that provides an interpretation of participants' ideas about higher-order questions and a model of the relationships among these ideas. Two hypotheses emerge from this framework. First, we propose that biologists look for ways to measure difficulty when writing higher-order questions. Second, we propose that biologists' assumptions about the role of questions in student learning strongly influence the types of higher-order questions they write.

  19. Prediction of pH-dependent aqueous solubility of druglike molecules

    DEFF Research Database (Denmark)

    Hansen, Niclas Tue; Kouskoumvekaki, Irene; Jørgensen, Flemming Steen

    2012-01-01

    In the present work, the Henderson-Hasselbalch (HH) equation has been employed for the development of a tool for the prediction of pH-dependent aqueous solubility of drugs and drug candidates. A new prediction method for the intrinsic solubility was developed, based on artificial neural networks...... that have been trained on a druglike PHYSPROP subset of 4548 compounds. For the prediction of acid/base dissociation coefficients, the commercial tool Marvin has been used, following validation on a data set of 467 molecules from the PHYSPROP database. The best performing network for intrinsic solubility...... predictions has a cross-validated root mean square error (RMSE) of 0.70 log S-units, while the Marvin pKa plug-in has an RMSE of 0.71 pH-units. A data set of 27 drugs with experimentally determined pH-solubility curves was assembled from the literature for the validation of the combined pH-dependent model...

  20. pK(a) based protonation states and microspecies for protein-ligand docking.

    Science.gov (United States)

    ten Brink, Tim; Exner, Thomas E

    2010-11-01

    In this paper we present our reworked approach to generate ligand protonation states with our structure preparation tool SPORES (Structure PrOtonation and REcognition System). SPORES can be used for the preprocessing of proteins and protein-ligand complexes as e.g. taken from the Protein Data Bank as well as for the setup of 3D ligand databases. It automatically assigns atom and bond types, generates different protonation, tautomeric states as well as different stereoisomers. In the revised version, pKa calculations with the ChemAxon software MARVIN are used either to determine the likeliness of a combinatorial generated protonation state or to determine the titrable atoms used in the combinatorial approach. Additionally, the MARVIN software is used to predict microspecies distributions of ligand molecules. Docking studies were performed with our recently introduced program PLANTS (Protein-Ligand ANT System) on all protomers resulting from the three different selection methods for the well established CCDC/ASTEX clean data set demonstrating the usefulness of especially the latter approach.

  1. New journal on biological frontiers

    Institute of Scientific and Technical Information of China (English)

    Weihua WU

    2010-01-01

    @@ Frontiers in Biology, an international peer-reviewed scientific journal to be published bi-monthly, is launched today. It is jointly published by Higher Education Press and Springer. The joumal provides a forum for a broad blend of peer-reviewed articles to promote rapid communication and exchanges among biologists around the world. The primary criterion for publication is new insights that are of broad interest to biologists, not just specialists, and the presentation of results must be appropriate to a wide audience of biologists.

  2. Fieldwork Report for the Nucleic Acid Technology Lab

    DEFF Research Database (Denmark)

    Ramos, Juan David Hincapie

    The development of new technologies requires an understanding of the social issues technologies would confront when deployed. Such is the case of e-Science solutions like the Mini-Grid, whose future users are molecular biologists. The successful adoption of the Mini-Grid requires its design...... to account to the existing conditions of the molecular biologists. In this technical report we present the results of an initial fieldwork study of molecular biologists. We present their organization structure, their roles, their tools, their activities, and information management behaviors and collaboration...

  3. Progeria: translational insights from cell biology.

    Science.gov (United States)

    Gordon, Leslie B; Cao, Kan; Collins, Francis S

    2012-10-01

    Cell biologists love to think outside the box, pursuing many surprising twists and unexpected turns in their quest to unravel the mysteries of how cells work. But can cell biologists think outside the bench? We are certain that they can, and clearly some already do. To encourage more cell biologists to venture into the realm of translational research on a regular basis, we would like to share a handful of the many lessons that we have learned in our effort to develop experimental treatments for Hutchinson-Gilford progeria syndrome (HGPS), an endeavor that many view as a "poster child" for how basic cell biology can be translated to the clinic.

  4. [Chronic wasting disease guidelines for the National Elk Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This memorandum provides the Regional Refuge Biologist some guidelines on transport of elk to or from chronic wasting disease (CWD) contaminated sites, and...

  5. Technical report: Water quality and metal and metalloid contaminants in sediments, and fish of Koyukuk, Nowitna, and the Northern Unit of Innoko National Wildlife Refuges, Alaska, 1991

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This study was conducted by U.S. Fish and Wildlife Service biologists during 1991. The study goals were to monitor water quality and concentrations of metals and...

  6. Intellectual pursuits of Nicolas Rashevsky the queer duck of biology

    CERN Document Server

    Shmailov, Maya M

    2016-01-01

    Who was Nicolas Rashevsky? To answer that question, this book draws on Rashevsky’s unexplored personal archival papers and shares interviews with his family, students and friends, as well as discussions with biologists and mathematical biologists, to flesh out and complete the picture. “Most modern-day biologists have never heard of Rashevsky. Why?” In what constitutes the first detailed biography of theoretical physicist Nicolas Rashevsky (1899-1972), spanning key aspects of his long scientific career, the book captures Rashevsky’s ways of thinking about the place mathematical biology should have in biology and his personal struggle for the acceptance of his views. It brings to light the tension between mathematicians, theoretical physicists and biologists when it comes to the introduction of physico-mathematical tools into biology. Rashevsky’s successes and failures in his efforts to establish mathematical biology as a subfield of biology provide an important test case for understanding the role o...

  7. Port Louisa National Wildlife Refuge Keithsburg Division Water and Sediment Quality Summary Report

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Biologists from the U.S. Fish and Wildlife Service surveyed environmental quality at a backwater system of the Upper Mississippi River between 1994 and 1996. The...

  8. Differential timing of gene expression regulation between leptocephali of North Atlantic eels in the Sargasso Sea

    DEFF Research Database (Denmark)

    Bernatchez, Louis; Saint-Cyr, Jérôme; Maes, Gregory E.;

    2011-01-01

    The unique life-history characteristics of North Atlantic catadromous eels have long intrigued evolutionary biologists, especially with respect to mechanisms that could explain their persistence as two ecologically very similar but reproductively and geographically distinct species. Differential ...

  9. Asbestos investigations in fish and wildlife in the upper Yukon River region, Alaska 1977-1982: Summary

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — High Concentrations of asbestos were first discovered in the upper Yukon River near Eagle, Alaska in the summer of 1977 by Fish and Wildlife Service Biologists....

  10. North Mississippi Refuge Complex Bird Observations 2008

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Bird observations on Coldwater River, Dahomey and Tallahatchie NWR in 2008 were recorded by the refuge biologist and several other birders. No sampling design was...

  11. North Mississippi Refuge Complex Bird Observations 2010

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Bird observations on Coldwater River NWR in 2010 were recorded by the refuge biologist and several other birders. No sampling design was used to generate the...

  12. North Mississippi Refuge Complex Bird Observations 2011

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Bird observations on Coldwater River and Tallahatchie NWR in 2011 were recorded by the refuge biologist and several other birders. No sampling design was used to...

  13. Tallahatchie NWR and Black Bayou Unit (Coldwater River NWR) Bird Observations 1996

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Anecdotal bird observations from Tallahatchie NWR, the Black Bayou Unit (Coldwater River NWR) surrounding areas throughout 1996 were recorded by the refuge biologist...

  14. North Mississippi Refuge Complex Bird Observations 2009

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Bird observations on Coldwater River and Tallahatchie NWR in 2009 were recorded by the refuge biologist and several other birders. No sampling design was used to...

  15. Dahomey NWR, Tallahatchie NWR and Coldwater River NWR Bird Observations 2003

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Anecdotal bird observations from Dahomey NWR, Tallahatchie NWR and Coldwater River NWR surrounding areas throughout 2003 were recorded by the refuge biologist and...

  16. Tallahatchie NWR and Black Bayou Unit (Coldwater River NWR) Bird Observations 1997

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Anecdotal bird observations from Tallahatchie NWR, the Black Bayou Unit (Coldwater River NWR) surrounding areas throughout 1997 were recorded by the refuge biologist...

  17. Tallahatchie NWR and Coldwater River NWR Bird Observations 2000

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Anecdotal bird observations from Tallahatchie NWR and Coldwater River NWR surrounding areas throughout 2000 were recorded by the refuge biologist and several other...

  18. Coldwater River NWR Bird Observations 2007

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Bird observations on Coldwater River NWR in 2007 were recorded by the refuge biologist and several other birders. No sampling design was used to generate the...

  19. Turnbull - Early Detection and Rapid Response Team 2011

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The AmeriCorps member, Refuge Wildlife Biologist, Volunteer Coordinator and Friends of Turnbull NWR will recruit and train volunteers in the use of GPS equipment,...

  20. Fishery Management Program Progress Report: Back Bay National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Memorandum containing summary of fishery biologist's visit to Back Bay to remove carp from impoundments at Back Bay National Wildlife Refuge.

  1. Organochlorine concentrations in burbot (Lota lota) livers from Fairbanks, Alaska, and, Kanuti, Tetlin and Yukon Flats National Wildlife Refuges, Alaska, 1998

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This study was conducted by U.S. Fish and Wildlife Service biologists during 1998 and 1999. Burbot liver was the tissue of choice for this study because chlorinated...

  2. Extracting biological knowledge from DNA sequences

    Energy Technology Data Exchange (ETDEWEB)

    De La Vega, F.M. [CINVESTAV-IPN (Mexico); Thieffry, D. [Universite Libre de Bruxelles, Rhode-Saint-Genese (Belgium)]|[Universidad Nacional Autonoma de Mexico, Morelos (Mexico); Collado-Vides, J. [Universidad Nacional Autonoma de Mexico, Morelos (Mexico)

    1996-12-31

    This session describes the elucidation of information from dna sequences and what challenges computational biologists face in their task of summarizing and deciphering the human genome. Techniques discussed include methods from statistics, information theory, artificial intelligence and linguistics. 1 ref.

  3. Scientists urge enforcement of an amphibian conservation plan

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ A group of CAS biologists recently lodged an appeal, calling for initiating a national action plan as soon as possible to protect the amphibian species now struggling for their survival throughout the country.

  4. Whooping Cranes During the 1985-1986 Winter

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report attempts to summarize whooping crane data collected by the Aransas biologist during the 1985-86 winter. It focuses on the distribution of the Wood...

  5. WormBase

    Data.gov (United States)

    U.S. Department of Health & Human Services — WormBase is an international consortium of biologists and computer scientists dedicated to providing the research community with accurate, current, accessible...

  6. VT Foote Brook Natural Channel Design Restoration 2001-2002

    Data.gov (United States)

    Vermont Center for Geographic Information — (Link to Metadata) The Foote Brook, located in Johnson, Vermont, is known to biologists and anglers as a high quality stream with significant natural reproduction of...

  7. VT Foote Brook Natural Channel Design Restoration 2003

    Data.gov (United States)

    Vermont Center for Geographic Information — (Link to Metadata) The Foote Brook, located in Johnson, Vermont, is known to biologists and anglers as a high quality stream with significant natural reproduction of...

  8. The Foote Brook Natural Channel Design Restoration Project (2001) and Post Monitoring Project (2002)--Johnson, Vermont

    Data.gov (United States)

    Vermont Center for Geographic Information — The Foote Brook, located in Johnson, Vermont, is known to biologists and anglers as a high quality stream with significant natural reproduction of rainbow, brown,...

  9. Post Monitoring (2003) of the Foote Brook Natural Channel Design Restoration Project--Johnson, Vermont

    Data.gov (United States)

    Vermont Center for Geographic Information — The Foote Brook, located in Johnson, Vermont, is known to biologists and anglers as a high quality stream with significant natural reproduction of rainbow, brown,...

  10. Instruction Manual and Frog Survey Protocols for Region 1 National Wildlife Refuges, East-side Zone

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This manual is intended to assist biologists wishing to conduct surveys for frogs and toads. The document includes detailed information on how to conduct surveys,...

  11. Fish stock surveys from 41 sites on the islands of Oahu and Hawaii from September 11, 1952 to December 28, 2000 (NODC Accession 0002754)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Data are from underwater visual surveys of fish stocks from 41 survey sites on the islands of Oahu and Hawaii, conducted by biologists and technicians of Hawaii's...

  12. Division of Aquatic Resources (DAR), Division of Lands and Natural Resources (DLNR) of the State of Hawaii Fish Stock Surveys from 41 sites on Oahu and Island of Hawaii from 1952-2000 (NODC Accession 0002754)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Data are from underwater visual surveys of fish stocks from 41 survey sites on the islands of Oahu and Hawaii, conducted by biologists and technicians of Hawaii's...

  13. Sacramento Metropolitan Area, California Reconnaissance Report

    Science.gov (United States)

    1989-02-01

    INTERVAL (YEARS) SACRAMENTO METROPOLITAN ARIA CALIFORNIA STAGE-FREQUENCY RELATIONSHIP SACRAMENTO RIVER AT FREMONT WEIR/WEST END SACRAMENTO DISTRICT...Wildlife Biologist/ Environmental Planner Karen Amerman Kuhn Civil Engineer/ Water Resources Plnr Patricia Roberson Environmental Studies

  14. Upper Mississippi River Floodplain water quality for Keithsburg Division, Illinois, Mark Twain National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Biologists from the U.S. Fish and Wildlife Service surveyed environmental quality at a backwater system of the Upper Mississippi River between 1994 and 1996. The...

  15. Modoc National Wildlife Refuge biological narrative 2009

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Report content includes information on the refuge wildlife biologist, biological aide, wildlife surveys, banding program, restoration projects, annual habitat,...

  16. Modeling regulatory networks with weight matrices

    DEFF Research Database (Denmark)

    Weaver, D.C.; Workman, Christopher; Stormo, Gary D.

    1999-01-01

    Systematic gene expression analyses provide comprehensive information about the transcriptional responseto different environmental and developmental conditions. With enough gene expression data points,computational biologists may eventually generate predictive computer models of transcription reg...

  17. William L Finley - Woody Vegetation Removal

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The initial project was targeted for ‘hidden prairies’ along Muddy Creek. With the loss of the supervisory biologist position, the focus of this project was changed...

  18. Stem cells: a plant biology perspective

    NARCIS (Netherlands)

    Scheres, B.J.G.

    2005-01-01

    A recent meeting at the Juan March Foundation in Madrid, Spain brought together plant biologists to discuss the characteristics of plant stem cells that are unique and those that are shared by stem cells from the animal kingdom

  19. Lessons from Embryos: Haeckel's Embryo Drawings, Evolution, and Secondary Biology Textbooks

    Science.gov (United States)

    Wellner, Karen L.

    2014-01-01

    In 1997, developmental biologist Michael Richardson compared his research team's embryo photographs to Ernst Haeckel's 1874 embryo drawings and called Haeckel's work "noncredible". "Science" soon published "Haeckel's Embryos: Fraud Rediscovered," and Richardson's comments further reinvigorated criticism of Haeckel by…

  20. Diversity in auxology: between theory and practice

    DEFF Research Database (Denmark)

    Hermanussen, M.; Lieberman, L. S.; Janewa, V. S.;

    2012-01-01

    Auxology has developed from mere describing child and adolescent growth into a vivid and interdisciplinary research area encompassing human biologists, physicians, social scientists, economists and biostatisticians. The meeting illustrated the diversity in auxology, with the various social, medic...

  1. Water quality, and metal and metalloid concentrations in water, sediment, and fish tissues from Innoko National Wildlife Refuge, Alaska, 1995-1997

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This study was conducted by U.S. Fish and Wildlife Service biologists from 1995-1997. The study goals were to determine selected metal and metalloid concentrations...

  2. Salmonids surveys, number of juvenile fish, fork length, and species diversity conducted in the Little Campbell Creek watershed, Alaska from 2010-11-01 to 2011-03-01 (NCEI Accession 0148761)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Over the past few years biologists and other researchers have encountered noticeable fish die-offs, mostly of young salmonid, in various stretches of Little Campbell...

  3. An evaluation based on goose nesting density of certain native land in holdings on the Yukon-Kuskokwim delta

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — In the fall of 1986, inquiries were made to research biologists working on the Yukon-Kuskokwim (Y-K) Delta concerning data that might help establish the value of...

  4. Cloud Technology May Widen Genomic Bottleneck - TCGA

    Science.gov (United States)

    Computational biologist Dr. Ilya Shmulevich suggests that renting cloud computing power might widen the bottleneck for analyzing genomic data. Learn more about his experience with the Cloud in this TCGA in Action Case Study.

  5. Deer carry capacity on the Rocky Mountain Arsenal National Wildlife Refuge based on dry matter intake and available dry matter residue

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — In a landscape dominated by urban development, the Rocky Mountain Arse:oal (RMA) is an especially important refuge for mule and white-tailed deer. RMA biologists...

  6. Aleutian Canada goose population and nest surveys at Agattu Island, Aleutian Islands, Alaska, spring 1985

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — From 6 to 26 June, six biologists made 231 observations of geese. Of this number, 43 were banded, 74 unbanded, and 114 undiscernible. From these observations it is...

  7. The 'atom-splitting' moment of synthetic biology: Nuclear physics and synthetic biology share common features

    OpenAIRE

    Valentine, Alex J; Kleinert, Aleysia; Verdier, Jerome

    2012-01-01

    Synthetic biology and nuclear physics share many commonalities in terms of public perception and funding. Synthetic biologists could learn valuable lessons from the history of the atomic bomb and nuclear power.

  8. Forecast effects of accelerating sea-level rise on the habitat of Atlantic Coast piping plovers and identify responsive conservation strategies

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This collaborative project will provide biologists and managers along the Atlantic coast with tools to predict effects of accelerating sea-level rise on the...

  9. Phenotypic flexibility and the evolution of organismal design

    NARCIS (Netherlands)

    Piersma, T; Drent, J

    2003-01-01

    Evolutionary biologists often use phenotypic differences between species and between individuals to gain an understanding of organismal design. The focus of much recent attention has been on developmental plasticity - the environmentally induced variability during development within a single genotyp

  10. Biological assessment of marine resources for the Republic of the Maldives, Indian Ocean, August, 2001 (NODC Accession 0000670)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — In August 2001, biologists from the U.S. Fish and Wildlife Service and the National Marine Fisheries Service were asked to conduct an assessment of the national...

  11. Biology HERO:CHARLES DARWIN%生物学英雄:查尔斯·达尔文

    Institute of Scientific and Technical Information of China (English)

    Robert Hole; 刘中飞

    2005-01-01

    @@ Charles Darwin did not come up with the idea of evdlution,he was merely the first to come up with an explanation for how evolution worked that explained what he and other biologists saw in the world.

  12. Branching processes in biology

    CERN Document Server

    Kimmel, Marek

    2015-01-01

    This book provides a theoretical background of branching processes and discusses their biological applications. Branching processes are a well-developed and powerful set of tools in the field of applied probability. The range of applications considered includes molecular biology, cellular biology, human evolution and medicine. The branching processes discussed include Galton-Watson, Markov, Bellman-Harris, Multitype, and General Processes. As an aid to understanding specific examples, two introductory chapters, and two glossaries are included that provide background material in mathematics and in biology. The book will be of interest to scientists who work in quantitative modeling of biological systems, particularly probabilists, mathematical biologists, biostatisticians, cell biologists, molecular biologists, and bioinformaticians. The authors are a mathematician and cell biologist who have collaborated for more than a decade in the field of branching processes in biology for this new edition. This second ex...

  13. Julia Butler Hansen NWR: Initial Survey Instructions for Audubon's Christmas Bird Count

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The CBC is one of the longest running population surveys in the country. It informs biologists on national trends and has contributed information on management...

  14. Baseline Marine Biological Survey Peacock Point Outfall and Other Point-Source Discharges, Wake Atoll, Pacific Ocean

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — On behalf of the U.S. Army Space and Missile Defense Command, biologists from the U.S. Fish and Wildlife Service and the National Marine Fisheries Service were...

  15. Balancing Demographic Benefits and Risks of Using Predator Exclosures on U.S. Atlantic Coast Piping Plover Nests

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Every year, shorebird biologists and beach managers decide whether to use wire cages (i.e., exclosures) to reduce predator access to nests of approximately 1,500...

  16. Population size and production of geese and eiders nesting on the Yukon-Kuskokwim Delta, Alaska in 1998

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Annual assessment of nesting populations of geese on the Yukon-Kuskokwim Delta(YKD) provides information for biologists, participants in cooperative goose...

  17. A change of course:JIPB to focus on fundamental questions in plant sciences

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ Benefited from the speedy development of omic tools and the use of model plants, such as rice, Arabidopsis and Medicargo, plant biologists have recently made tremendous breakthroughs in understanding plant growth,development, and response to environmental changes.

  18. Site 300 Bat Monitoring Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Drennan, Joe [Garcia and Associates, San Francisco, CA (United States); Tortosa, Justin [Garcia and Associates, San Francisco, CA (United States)

    2016-07-18

    From June 15 to 18, 2015, GANDA biologist Graham Neale assisted in programming and fieldtesting of the bat monitoring equipment. The equipment was deployed in the field on a meteorological (MET) tower within Site 300 on June 18, 2015.

  19. 77 FR 12611 - Endangered Species Recovery Permit Applications

    Science.gov (United States)

    2012-03-01

    ... FURTHER INFORMATION CONTACT: Daniel Marquez, Fish and Wildlife Biologist; see ADDRESSES (telephone: 760... information--may be made publicly available at any time. While you can ask us in your comment to withhold...

  20. Sharing seabird stories in the Bering Sea

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — In March 2003, biologists from the U.S. Fish and Wildlife Service, Audubon Alaska, Kodiak Audubon, and Oregon State University spent a week in the village of...

  1. Population dynamics of the king rails, Rallus elegans

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report describes the findings of research conducted by a team of biologists from East Carolina University. The project ‘Population Dynamics of the King Rail,...

  2. AFSC/NMML: Bowhead whale aerial surveys and photography near Barrow, Alaska, from 1979-1992

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Bowhead whales were documented during their spring migration most years from 1979 to 1992 by biologists from NMML. This documentation consisted of flying aerial...

  3. Lacreek NWR pelican disease outbreak briefing

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Briefing for the Region 6 Regional Biologist on a disease outbreak at Lacreek National Wildlife Refuge. Pelican were the most affected species by the outbreak. It is...

  4. Delmarva Fox Squirrel Refuge Tour Report

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This is a report by members of the Delmarva Fox Squirrel Recovery Team, the South Zone Biologist, and the Regional Forester that summarizes a tour of Chincoteague...

  5. John Iiames, Ph.D.

    Science.gov (United States)

    Research Biologist within the Landscape Characterization Branch at the U.S. EPA, Research Triangle Park, NC. He is the Principal Investigator for EPA MODIS LAI validation research examining the needle-leaf biome in the southeastern U.S.

  6. Inelastic scattering of neutrons and possible biological applications.

    Science.gov (United States)

    Egelstaff, P A

    1976-05-01

    The field of neutron inelastic scattering has probably been developed to the stage where it can begin to help the biologist. Because essentially no experimental data have been obtained, it is difficult either to draw conclusions or to make forecasts except on the basis of general hypotheses. It seems likely, however, that the next stage is up to biologists. After reviewing those biological problems in which molecular dynamics might play an important role, they should suggest specimens of interest which can give inelastic peaks with existing spectrometers operating with 5 to 10-A neutrons at angles greater than 5degrees and with resolutions of approximately 50 mueV. These specimens may involve molecules slightly smaller and more mobile than some biologists would like, but a successful outcome might lead to the development of spectrometers capable of working in a more satisfactory range. In this event the return may well prove rewarding to the biologists.

  7. MA Common Tern Census

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The official State census period for common terns was June 1-10. The survey was conducted on June 4 by Biologist Healey, Biotech Springfield, and Maintenance...

  8. Marine molecular biology: An emerging field of biological sciences

    Digital Repository Service at National Institute of Oceanography (India)

    Thakur, N.L.; Jain, R.; Natalio, F.; Hamer, B.; Thakur, A.N.; Muller, W.E.G.

    to tackle problems associated with global climate changes, bio- diversity, environmental quality and use of marine living re- sources (Molecular biology in marine science, 1994). Marine biologists study oceanic life in relation to marine environment... that often range from small to global scale, whereas, molecular biologist study biological events in terms of the physiochemical properties of molecules. The immediate benefits of the collab- orative research between these two disciplines could include...

  9. Recent microwave research studies of Gazi Biophysics & Gazi Non-Ionizing Radiation Protection Center

    OpenAIRE

    SEYHAN, Nesrin

    2013-01-01

    Gazi Biophysics is located in Ankara at the Medical Faculty of Gazi University and has been carrying out in vivo and in vitro research studies on the biological impacts of Static, Extremely Low Frequency (ELF) and Microwave (MW) electromagnetic fields (EMF) since 1989. Our laboratory includes: Physicists, biologists, electrical engineers, all of whom are studying how living systems respond to EMF. Our research team includes physicists, biologists, electrical engineers, physicians, biochemists...

  10. Exclusive Multipotency and Preferential Asymmetric Divisions in Post-Embryonic Neural Stem Cells of the Fish Retina

    OpenAIRE

    Centanin, L.; Ander, J.-J.; Hoeckendorf, B.; Lust, K.; T. Kellner; Kraemer, I.; Urbany, C.; Hasel, E.; Harris, W.A.; Simons, B. D.; Wittbrodt, J

    2014-01-01

    This is the final version of the article. It has been published by The Company of Biologists Ltd in Development here: http://dev.biologists.org/content/early/2014/08/19/dev.109892.long. The potency of post-embryonic stem cells can only be addressed in the living organism, by labeling single cells after embryonic development and following their descendants. Recently, transplantation experiments involving permanently labeled cells revealed multipotent neural stem cells (NSCs) of embryonic or...

  11. Flow cytometry: retrospective, fundamentals and recent instrumentation

    OpenAIRE

    Picot, Julien; Guerin, Coralie L; Le Van Kim, Caroline; Boulanger, Chantal M.

    2012-01-01

    Flow cytometry is a complete technology given to biologists to study cellular populations with high precision. This technology elegantly combines sample dimension, data acquisition speed, precision and measurement multiplicity. Beyond the statistical aspect, flow cytometry offers the possibility to physically separate sub-populations. These performances come from the common endeavor of physicists, biophysicists, biologists and computer engineers, who succeeded, by providing new concepts, to b...

  12. Are physicists afraid of mathematics?

    OpenAIRE

    Kollmer, Jonathan E.; Pöschel, Thorsten; Gallas, Jason A. C.

    2015-01-01

    A recent study claimed that heavy use of equations impedes communication among biologists, as measured by the ability to attract citations from peers. It was suggested that to increase the probability of being cited one should reduce the density of equations in papers, that equations should be moved to appendices, and that math training among biologists should be improved. Here, we report a detailed study of the citation habits among physicists, a community that has traditionally strong train...

  13. Supersymmetry and the relationship between a class of singular potentials in arbitrary dimensions

    CERN Document Server

    Gönül, B; Koçak, M; Tutcu, D; Cancelik, Y

    2001-01-01

    The eigenvalues of the potentials $V_{1}(r)=\\frac{A_{1}}{r}+\\frac{A_{2}}{r^{2}}+\\frac{A_{3}}{r^{3}}+\\frac{A_{4 }}{r^{4}}$, $V_{2}(r)=B_{1}r^{2}+\\frac{B_{2}}{r^{2}}+\\frac{B_{3}}{r^{4}}+\\frac{B_{4}}{r^ {6}}$, and of the special cases of these potentials such as the Kratzer and Goldman-Krivchenkov potentials, are obtained in $N$-dimensional space. The explicit dependence of these potentials in higher-dimensional space is discussed, which have not been previously linked.

  14. Lower-zone emphysema in young patients without α1-antitrypsin deficiency

    Science.gov (United States)

    Martelli, Nestor A.; Goldman, Ernesto; Roncoroni, Aquiles J.

    1974-01-01

    Martelli, N. A., Goldman, E., and Roncoroni, A. J. (1974).Thorax, 29, 237-244. Lowerzone emphysema in young patients without α1-antitrypsin deficiency. Three young patients with radiographic pulmonary emphysema predominantly in the lower zones are reported. The clinical and physiological features were those observed in severe pulmonary emphysema. Predominance of the main lesions in the lower zones was confirmed in two cases by selective pulmonary angiography. One of the patients died and extensive panlobular emphysema was found at necropsy. Although the similarities between our patients and those with emphysema and α1-antitrypsin deficiency were remarkable, the latter condition was ruled out. Images PMID:4545502

  15. Grecia, crónica de un desastre anunciado

    OpenAIRE

    Gabellini, Giacomo

    2016-01-01

    La crisis griega se remonta, especialmente al 2009, cuando se hicieron conocidos los auténticos datos sobre el estado real de la economía nacional. Para ocultar los datos verdaderos, los líderes griegos recurrieron a la ayuda de los bancos de Inversión Goldman Sachs y JP Morgan Chase falsificando las cuentas y permitiendo al país unirse a la “zona euro”. Con el ascenso del partido socialista PASOK, el verdadero estado de las cuentas públicas fue dado a ...

  16. Who Dominates the Semi-submersible Rig Market?

    Institute of Scientific and Technical Information of China (English)

    Yang Qingxia; Liu Chengming; LiangYuanhua

    2011-01-01

    Currently, the US and Europe are the centers for the design of semi-submersible rigs.The American company FRIEDE & GOLDMAN was founded in the 1950s. At present, over 100 mobile offshore drilling units and production platforms in the world are designed by this company, which mainly has two types of deepwater semi-submersible rig, F&GExD and MillenniumSA. F&GExD is the semi-submersible rig of the sixth generation and its operational depth can reach up to 3050m. MillenniumSA is semi-submersible rig of the fifth and half generation with an operational depth of 2400m.

  17. Leaders break ground for INFINITY

    Science.gov (United States)

    2008-01-01

    Community leaders from Mississippi and Louisiana break ground for the new INFINITY at NASA Stennis Space Center facility during a Nov. 20 ceremony. Groundbreaking participants included (l to r): Gottfried Construction representative John Smith, Mississippi Highway Commissioner Wayne Brown, INFINITY board member and Apollo 13 astronaut Fred Haise, Stennis Director Gene Goldman, Studio South representative David Hardy, Leo Seal Jr. family representative Virginia Wagner, Hancock Bank President George Schloegel, Mississippi Rep. J.P. Compretta, Mississippi Band of Choctaw Indians representative Charlie Benn and Louisiana Sen. A.G. Crowe.

  18. Discrepancias entre diagnósticos clínicos y hallazgos de autopsia

    OpenAIRE

    María Virginia Bürgesser; Diego Camps; Patricia Calafat; Ana Diller

    2011-01-01

    El objetivo principal del presente trabajo fue identificar las discrepancias clínico-patológicas en las autopsias realizadas en la institución. Se revisaron 53 autopsias de casos clínicos en adultos en el período comprendido entre enero de 2005 y junio de 2009, realizadas en el servicio de Anatomía Patológica del Hospital Privado de Córdoba, Argentina. Se excluyeron seis debido a información insuficiente. Se aplicó la clasificación de Goldman y col. para establecer las discrepancias clínico-p...

  19. Coming to see objects of knowledge: Guiding student conceptualization through teacher embodied instruction in a robotics programming class

    Science.gov (United States)

    Kwah, Helen

    This thesis explores the questions of how a teacher guides students to see concepts, and the role of gesture and gesture viewpoints in mediating the process of guidance. To examine these questions, two sociocultural theoretical frameworks--Radford's cultural-semiotic theory of knowledge objectification (e.g., 2003), and Goldman's Points of Viewing theory (e.g., 2007)--were applied to conduct a microanalytic, explanatory case study of the instructional activity of an exemplary teacher and his students in a middle school robotics programming class. According to Radford, students acquire concepts as they draw upon semiotic resources such as language and gesture to generalize and objectify initially concrete perceptions and actions. I applied Radford's framework to explain the mediations that a teacher might enact in guiding students to objectify and see concepts. Furthermore, I focused on gesture as semiotic means because of emergent research on gesture's role in communicating the visuospatial imagery that underlies math/ scientific concepts. I extended the view of gestures to the viewpoints constructed in gesture, and applied Goldman's theory to explain how perspectives might be actively constructed and shared in the process of guiding student conceptualization. Data was collected over a semester through participant observation, field notes, teacher and student interviews, and reviews of artifacts. Multimodal microanalyses were conducted on video data from eight class sessions. The findings provide confirmations and some disconfirmations about the applicability of Radford's and Goldman's theories for explaining a teacher's process of guiding student conceptualization. Notably, some of Radford's notions about de-contextualization and symbolic generalizations were not confirmed. Overall, the findings are summarized through three themes including, grounding, and perceptual organizers as two ways that gesture and other means served to both index and identify action

  20. 女性创业的商业策略

    Institute of Scientific and Technical Information of China (English)

    陶子

    2011-01-01

    当苏珊妮·谢(SuzanneXie)辞去高盛集团(GoldmanSachs)资产管理工作专注于她创办的企业时,她还申请了星巴克(Starbucks)兼职店员的工作,因为她觉得,自己可以用这种方式获得这家咖啡连锁店提供的医疗保险。

  1. Alcohol and drug expectancies as anticipated changes in affect: negative reinforcement is not sedation.

    Science.gov (United States)

    Wiers, Reinout W

    2008-01-01

    Goldman and Darkes (2004) argued that all three basic alcohol-expectancy factors can be assessed with a brief questionnaire (AEMax), related to the circumplex model of emotion. I argue that negative reinforcement, one of the three basic expectancy factors, is not assessed with the AEMax. Importantly, negative reinforcement is positively related to problem drinking while sedation (the AEMax-factor that comes closest) is not. In a new dataset (from 119 students, collected in 2002), I demonstrate that sedation is related to negative expectancies and not to negative reinforcement. Different ways to assess all major expectancy factors are proposed.

  2. The role of dermatologists in the evolution of laser surgery.

    Science.gov (United States)

    Wheeland, R G; McBurney, E; Geronemus, R G

    2000-09-01

    The role dermatologists have played throughout the history of laser development is an extremely vital one. The initial interests of Dr. Leon Goldman stimulated many other individual dermatologists to further his work and develop surgical techniques using newer laser systems to provide more effective treatment for patients with a variety of skin diseases. The long list of current cutaneous laser applications developed by dermatologists makes it virtually certain that members of our specialty will continue to play a significant future role in the refinement of laser instrumentation and operative techniques that are inevitable to occur.

  3. Experimental design in phylogenetics: testing predictions from expected information.

    Science.gov (United States)

    San Mauro, Diego; Gower, David J; Cotton, James A; Zardoya, Rafael; Wilkinson, Mark; Massingham, Tim

    2012-07-01

    Taxon and character sampling are central to phylogenetic experimental design; yet, we lack general rules. Goldman introduced a method to construct efficient sampling designs in phylogenetics, based on the calculation of expected Fisher information given a probabilistic model of sequence evolution. The considerable potential of this approach remains largely unexplored. In an earlier study, we applied Goldman's method to a problem in the phylogenetics of caecilian amphibians and made an a priori evaluation and testable predictions of which taxon additions would increase information about a particular weakly supported branch of the caecilian phylogeny by the greatest amount. We have now gathered mitogenomic and rag1 sequences (some newly determined for this study) from additional caecilian species and studied how information (both expected and observed) and bootstrap support vary as each new taxon is individually added to our previous data set. This provides the first empirical test of specific predictions made using Goldman's method for phylogenetic experimental design. Our results empirically validate the top 3 (more intuitive) taxon addition predictions made in our previous study, but only information results validate unambiguously the 4th (less intuitive) prediction. This highlights a complex relationship between information and support, reflecting that each measures different things: Information is related to the ability to estimate branch length accurately and support to the ability to estimate the tree topology accurately. Thus, an increase in information may be correlated with but does not necessitate an increase in support. Our results also provide the first empirical validation of the widely held intuition that additional taxa that join the tree proximal to poorly supported internal branches are more informative and enhance support more than additional taxa that join the tree more distally. Our work supports the view that adding more data for a single (well

  4. Building a sustainable future - The effects of CSR-finance on national oil companies

    Energy Technology Data Exchange (ETDEWEB)

    Thakur, Vishal

    2010-09-15

    Since the release of Goldman Sach's 'Path to 2050' report, arguing the combined economies of Brazil, Russia, India and China, would ellipse the economies of the current richest countries by 2050, the BRIC countries have garnered global attention. As demand for oil in these nations increases, NOCs within the BRIC have gone beyond national borders for exploration and financing - giving rise to concerns over emerging policies, objectives and priorities. The purpose of this paper is to examine NOCs of the BRIC and their compliance with international standards of corporate social responsibility and their effects through international capital markets.

  5. Social Epistemology: 5 Questions

    DEFF Research Database (Denmark)

    Social Epistemology: 5 Questions is a collection of interviews with some of the world’s most influential scholars working on social epistemology from a range of disciplinary perspectives. We hear their views on social epistemology; its aim, scope, use, broader intellectual environment, future...... direction, and how the work of the interviewees fits in these respects. Interviews with David Bloor, Cristina Bicchieri, Richard Bradley, Lorraine Code, Hans van Ditmarsch, Miranda Fricker, Steve Fuller, Sanford Goldberg, Alvin Goldman, Philip Kitcher, Martin Kusch, Jennifer Lackey, Helen E. Longino, Philip...

  6. Normatividade e Investigação

    Directory of Open Access Journals (Sweden)

    Luiz Henrique de A. Dutra

    1999-06-01

    Full Text Available This paper aims at dealing with the problem of normativity as regards naturalized epistemologies. According to Quine's view in "Epistemology Naturalized" normativity is to be ruled out from epistemology altogether. However, some other naturalists and Quine himself in later works revise that doctrine. Particularly, Richard Boyd and Alvin Goldman's stances are reviewed here, in addition to Quine's later view according to which normativity concerns "applied" epistemology. Finally, a further solution is proposed, which stems from an analysis of the pragmatics of investigation. According to this view normativity is a feature of our investigations; it is not related to epistemology as a discipline.

  7. Discrepancias entre diagnósticos clínicos y hallazgos de autopsia Discrepancies between clinical diagnoses and autopsy findings

    OpenAIRE

    María Virginia Bürgesser; Diego Camps; Patricia Calafat; Ana Diller

    2011-01-01

    El objetivo principal del presente trabajo fue identificar las discrepancias clínico-patológicas en las autopsias realizadas en la institución. Se revisaron 53 autopsias de casos clínicos en adultos en el período comprendido entre enero de 2005 y junio de 2009, realizadas en el servicio de Anatomía Patológica del Hospital Privado de Córdoba, Argentina. Se excluyeron seis debido a información insuficiente. Se aplicó la clasificación de Goldman y col. para establecer las discrepancias clínico-p...

  8. Counterfactual Reasoning for Regretted Situations Involving Controllable Versus Uncontrollable Events: The Modulating Role of Contingent Self-Esteem

    OpenAIRE

    2015-01-01

    We report a study that examined the modulating impact of contingent self-esteem on regret\\ud intensity for regretted outcomes associated with controllable versus uncontrollable events.\\ud The Contingent Self-Esteem Scale (e.g., Kernis & Goldman, 2006) was used to assess the extent\\ud to which a person’s sense of self-worth is based on self and others’ expectations. We found\\ud that there was an influence of self-esteem contingency for controllable but not for uncontrollable\\ud regret types. F...

  9. High-energy Nd:glass laser for oncology

    Science.gov (United States)

    Boutchenkov, Vyatcheslav A.; Utenkov, Boris I.; Zaitsev, V. K.; Bayanov, Valentin I.; Serebryakov, Victor A.

    1991-07-01

    The use of high energy solid state lasers for the treatment of human skin neoplasia was based on the experiments and clinic studies by Helsper and Goldman (1964), McGuff (1966). The heat of precise local volume is emitted due to the pulse laser radiation. The thermal effect results in the superficial necrosis of tissues with their integrity destruction, vascular repture accompanied by bloodstoke in some cases and by capillary embolism in others. Obvious tumour destruction is note only in case of high density irradiation. General tumour destruction depends on biological neoplasia features as well as the laser type.

  10. Mario Bunge y la verdad como correspondencia en términos psicofisiológicos

    OpenAIRE

    Garay, Carlos Alberto

    1996-01-01

    La teoría de la correspondencia de la verdad es una de las más desprestigiadas. Ciertamente, como ha sido observado en diversas oportunidades (Pitcher 1964, Haack 1982, Prior 1967, Johnson 1992, Devitt 1988, Goldman 1986, Walker 1989), ha tenido dificultades no sólo al tratar de establecer que tipo de relación es la correspondencia sino también al investigar cuáles son los elementos que deberían integrar esa relación. En una epistemología naturalizada neurofisiológicamente debemos aceptar las...

  11. Properties of a conductive cellular chloride pathway in the skin of the toad (Bufo bufo)

    DEFF Research Database (Denmark)

    Larsen, Erik Hviid; Kristensen, P

    1978-01-01

    of the steady-state conductance and the steady-state chloride current reveal that the chloride pathway has maximum conductance for V approximately -80 mV (outside of the skin being negative) and approaches a non-conducting safe for V greater than 0 mV. This strong outward going rectification is a steady......-compartment model indicate that the strong steady-state chloride current rectification cannot be obtained if only the intracellular chloride concentration and the membrane potentials are allowed to vary ("Goldman-rectification"). It is suggested, therefore, that the premeability of the chloride pathway varies...

  12. 20th Anniversary Conference on World Bank Administrative Tribunal

    CERN Document Server

    2000-01-01

    Contents :"Review of discretionary power by international administrative tribunals" by Michel Gentot, "Checks exerted by administrative tribunals over the discretionary powers of international organizations" by Nicolas Valticos, "Comments" by Ranjan (C.F.) Amerasinghe, "The review of managerial discretion by international administrative tribunals" by Francisco Orrego Vicuña, "Some practical issue arising in international administrative tribunals" by Nassib G. Ziadé, "Aspects of judicial review of administrative action in the WBAT with comparative remarks" by Spyridon Flogaitis, "The International Monetary Fund Administrative Tribunal : its first six years" by Celia Goldman

  13. Virtual Representation of IID Observations in Bayesian Belief Networks

    Science.gov (United States)

    1994-04-01

    Environmental Sciences 1911 North Ft Myer Drive Ddpartement d’itudes en Education. AFOSRINL Ni Suite 1100 et d’admlnistration do 1’ Educaion , Bldg 410...Stree College Park MD 20742 PittMbuh PA 15260 Dr Mashall J Farr Dr Sharon Dery Farr-Siht Co Dr Suian R Goldman Flrida State University 2520 North Vernon...of Statistics Dr William Koch lantitut fur Psydiologie Pittsburgh PA 15213 Born 7246 RW1H Aachen Mess A Eval Center Jaegeastraise 17/19 Dr Marcel Just

  14. BRICs钢铁业的现状与展望(上)

    Institute of Scientific and Technical Information of China (English)

    贾成厂

    2008-01-01

    最近,BRICs(金砖四国)的概念在媒体的经济栏与经济杂志中频频出现。BRIC是由巴西(Brazil)、俄罗斯(Russia)、印度(India)、中国(China)四个国家的开头字母所组成。自从美国的大证券公司Goldman Sachs(高盛集团)2003年秋在对于投资者的报告中使用以来,在人们中广为流传。

  15. 心理治疗中共同要素理论的历史发展%The Common Factors Theory and Its Historical Development in Psychotherapy

    Institute of Scientific and Technical Information of China (English)

    杨文登

    2016-01-01

    从共同要素的角度,分理论模式化与研究实证化两条线索,追溯了心理治疗中共同要素理论的思想渊源,并自Saul Rosenzweig开始,综述了Carl Rogers、Jerome Frank、Marvin Goldfried、Michael Lambert、Bruce Wampold等学者的观点,探讨了共同要素理论的历史演进、内涵结构、理论模式及当代研究进展.认为它在不久的未来,将与特殊技术说逐步走向整合,加深对心理治疗过程与改变机制的认识,共同提升心理治疗的效果.

  16. Impact of rivaroxaban on stent thrombosis and secondary prevention of cardiovascular events in acute coronary syndrome

    Directory of Open Access Journals (Sweden)

    Krohn-Grimberghe M

    2014-05-01

    Full Text Available Marvin Krohn-Grimberghe, Christoph Bode, Constantin von zur MuhlenDepartment of Cardiology and Angiology I, Heart Center, University of Freiburg, GermanyAbstract: Angioplasty and stent implantation have greatly improved the outcome of patients with acute coronary syndrome. However, stents come with the risk of stent thrombosis, which is associated with a high rate of revascularization, myocardial infarction, and death. The inhibition of factor Xa due to rivaroxaban leads to an interruption of the intrinsic as well as the extrinsic coagulation pathway, which reduces thrombus formation as a potential mechanism to diminish the rate of stent thrombosis. In this review, we evaluate the role of rivaroxaban in the prevention of stent thrombosis and its general role in patients with acute coronary syndrome.Keywords: Rivaroxaban, stent thrombosis, acute coronary syndrome, secondary prevention

  17. Strategic urban governance of transition in household practices

    DEFF Research Database (Denmark)

    Quitzau, Maj-Britt; Hoffmann, Birgitte; Hansen, Trine Bang

    2013-01-01

    technologies at the urban scale. In doing this, we more specifically challenge the technological emphasis in strategic niche management (Kemp et al. 1998) by pointing to developing a broader conception of niche management, which also addresses changes in daily routines of practitioners. We forward this point...... discusses the challenge of strategically promoting sustainable practices through governance initiatives at the urban scale. An important argument in the paper is that local authorities are well positioned to take on the challenge of engaging with transitions in household practices, which underlines...... priorities (Hodson and Marvin 2010). It has been argued that such governance initiatives do seldom represent transition paths in themselves, due to the delimited focus on the urban scale (Geels 2011). However, these governance initiatives still represent important transition activities that need...

  18. Analysing the relationship between urban livelihoods and water infrastructure in three settlements in Cusco, Peru.

    Science.gov (United States)

    Crawford, Catherine; Bell, Sarah

    2012-01-01

    This paper explores the role played by water infrastructure in urban livelihoods. It is based on a study of three settlements in Cusco, Peru, and shows that different modes of organising infrastructure co-exist within the same city, despite national policy prescriptions for urban water provision. Further, unequal access of households to these services exists within the same settlements and amplifies household vulnerability which, in turn, feeds back to undermine local, autonomous governance of water. This paper draws on the work of van Vliet et al. and Marvin and Graham to develop a framework that considers infrastructure organisation alongside household livelihoods in order to analyse the features of governance and vulnerability that affect urban livelihoods by privileging some groups and bypassing others.

  19. Book Review of: "The Social Context View of Sociology "

    Directory of Open Access Journals (Sweden)

    Kathryn Schmidt

    2008-10-01

    Full Text Available Readers seeking coherent sociological explanations for social inequality and oppression also will be disappointed in the book's content. The authors' focus on structural influences on social experiences glosses over experiences of oppression and inequality important to Marxist, feminist, and other 'conflict theory' traditions. However, The authors offer a book that will satisfy those who seek a book that is easily readable, replete with examples, and offers a coherent structurally focused overview of sociology. The authors draw on Marvin Olsen's (1968 nine layers of social organization to provide a framework for exploring major issues and institutions. The authors’ teaching experience shows in their ability to pace the material and use their model's levels of analysis to organize each chapter.

  20. 汽车城的衰退

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    下面这些已经消失的汽车城音乐当家花旦们,如今,也许只有再怀念一下的份了……注:汽车城音乐是一种起源于底特律的黑人音乐。1 G1adys Knight & The Pips 的‘I HeardIt ThOUgh The Grapevine’也许你会更喜欢 Marvin Gdye 的版本,但那你就错了。因为不论是他们谁的版本,这首歌都是流行音乐史上最棒的歌曲。收藏于:Mod Fave Raves Vol 1(汽车城音乐)

  1. Linguistique informatique : Traduction automatique

    OpenAIRE

    Danlos, Laurence

    2000-01-01

    Dans le célèbre film "2001, L'Odyssée de l'espace" de S. Kubrik, l'ordinateurHAL comprend l'homme, dialogue avec lui dans sa langue, exécute sescommandes, et ressent des émotions. En 1968, Marvin Minsky, conseillerscientifique du film en tant que spécialiste de L'Intelligence Artificielle,pensait qu'on pourrait effectivement réaliser un ordinateur tel que HAL en2001. En l'an 2000, est-on prêt de la réalisation de HAL ? Cet articleessayera de montrer et d'expliquer pourquoi on en est loin....

  2. Politically Correct Racism and the Geisha Novel: The Psychology of Sophisticated Racism Mirrors that of Ethnic Jokes

    Directory of Open Access Journals (Sweden)

    TANAKA, Tomoyuki

    2006-01-01

    Full Text Available In Section 1, politically correct racism (PC racism is defined as an act with racist intent, justified by righteous appearance, with popularity or near-total acceptance because of its righteous appearance. In Section 2, after presenting a theory of jokes based on analyses by Sigmund Freud and Marvin Minsky, I show that the pleasure one derives from PC racism is similar to that derived from ethnic jokes. In Section 3, I point out the inaccuracies and prejudice contained in the novel Memoirs of a Geisha by comparing it with the Japanese version. Based on the study by Anne Allison of the American reception of the novel, I explain its surprising popularity using PC racism. Pleasures of romanticized subjugation and pleasures of hating the Japanese are made acceptable by the politically-correct appearance. Finally in Section 4, I characterize the geisha film as a watered-down version with the novel's most racist elements removed.

  3. Removing the center from computing: biology's new mode of digital knowledge production.

    Science.gov (United States)

    November, Joseph

    2011-06-01

    This article shows how the USA's National Institutes of Health (NIH) helped to bring about a major shift in the way computers are used to produce knowledge and in the design of computers themselves as a consequence of its early 1960s efforts to introduce information technology to biologists. Starting in 1960 the NIH sought to reform the life sciences by encouraging researchers to make use of digital electronic computers, but despite generous federal support biologists generally did not embrace the new technology. Initially the blame fell on biologists' lack of appropriate (i.e. digital) data for computers to process. However, when the NIH consulted MIT computer architect Wesley Clark about this problem, he argued that the computer's quality as a device that was centralized posed an even greater challenge to potential biologist users than did the computer's need for digital data. Clark convinced the NIH that if the agency hoped to effectively computerize biology, it would need to satisfy biologists' experimental and institutional needs by providing them the means to use a computer without going to a computing center. With NIH support, Clark developed the 1963 Laboratory Instrument Computer (LINC), a small, real-time interactive computer intended to be used inside the laboratory and controlled entirely by its biologist users. Once built, the LINC provided a viable alternative to the 1960s norm of large computers housed in computing centers. As such, the LINC not only became popular among biologists, but also served in later decades as an important precursor of today's computing norm in the sciences and far beyond, the personal computer.

  4. Reply [to “Comment on ‘Assessing flood hazard on dynamic rivers’”

    Science.gov (United States)

    Pinter, Nicholas; Thomas, Russell; Wlosinski, Joseph H.

    We welcome the comments by D. M. Goldman, J. R. Olsen, and S. K. Nanda of the U.S. Army Corps of Engineers on our analyses of flood trends on the Middle Mississippi River (MMR) and on our assertion that historical stage data can be utilized in flood-frequency analysis. In some cases, the comments by the Corps authors point out legitimate limitations in the technique presented in our original article—limitations that we also have pointed out (for example, to funding agencies) as directions for future refinement. In other cases, Goldman et al. repeat arguments that have been used for decades to stymie attempts to link river engineering activities to worsening flood behavior. We welcome the opportunity to review these arguments under the spotlight of rigorous analysis. Finally, a major purpose of the Pinter et al. [2001] paper was to show that historical stage data represent an underutilized resource that has promise as a supplement to, and an independent test of discharge-based, model-driven analyses of flood frequency.

  5. Lamotheoxyuris ackerti n. gen., n. comb. (Nematoda: Heteroxynematidae parasite of Neotoma spp. (Rodentia: Muridae Lamotheoxyuris ackerti n. gen., n. comb. (Nematoda: Heteroxynematidae parásito de Neotoma spp. (Rodentia: Muridae

    Directory of Open Access Journals (Sweden)

    JORGE FALCÓN-ORDAZ

    2010-06-01

    Full Text Available On the basis of the revision of the type material of Aspiculuris ackerti Kruidenier & Mehra, 1959, and new specimens collected from Neotoma nelsoni Goldman, 1905 (Rodentia: Cricetidae, in Veracruz, Mexico, we herein to which A. ackerti is transferred as Lamotheoxyuris ackerti This new genus differs from all other genera included in 1 mouth surrounded by six lips; 2 extension of lateral alae describe a new genus (Lamotheoxyuris n. gen., (Kruidener & Mehra, 1959 n. gen., n. comb. Heteroxynematinae by the following main traits: reduced; and 3 lack of caudal alae.Con base en la revisión del material tipo de Aspiculuris ackerti Kruidenier y Mehra, 1959 y de nuevos ejemplares recolectados en Neotoma nelsoni Goldman, 1905 (Rodentia: Cricetidae, en Veracruz, México, se describe un nuevo género (Lamotheoxyuris n. gen., al que A. ackerti es transferido como Lamotheoxyuris ackerti (Kruidener y Mehra, 1959 n. gen., n. comb. Este nuevo género se distingue de todos los demás géneros incluidos en Heteroxynematinae por las siguientes características: 1 presencia de seis labios rodeando la boca; 2 extensión reducida del ala lateral; y 3 carencia de ala caudal.

  6. Problematic Protagonist in the Novels of Modir-e Madrese and Sovashoon

    Directory of Open Access Journals (Sweden)

    a Hassanzadeh Mirali

    2011-06-01

    Full Text Available Owing to have the capability of representing realities of life, novel has replaced epic in the age of Renaissance and industrial revolution and in the first half of the 20th century. George Lukacs has introduced realistic novel as the main form of literary genres corresponding with bourgeois society. Later on his follower, Lucien Goldman, has considered any literary work which is compatible with realism as a valuable work. Therefore, according to these two Marxist thinkers, there are a number of characters who are problematic due to their commitment to sound values and principles in realistic novels. According to Lukacs and Goldman problematic protagonist is a problematic, futureless and protesting person who inquires about noble and original human values. Considering a number of similarities and differences, the action and performance of such protagonists also exist in Iranian realistic novels. In this study as the problematic protagonist is described and explained, the novels of Modir-e Madrese (school head by Jalal-e Al-e Ahmad and Sovashoon by Simin-e Daneshvar are analyzed with regard to this aspect. The protagonists of these two novels (the head and Yousef are introduced as problematic characters because of their disagreement with corrupt society.

  7. On Codazzi tensors on a hyperbolic surface and flat Lorentzian geometry

    CERN Document Server

    Bonsante, Francesco

    2015-01-01

    Using global considerations, Mess proved that the moduli space of globally hyperbolic flat Lorentzian structures on $S\\times\\mathbb{R}$ is the tangent bundle of the Teichm\\"uller space of $S$, if $S$ is a closed surface. One of the goals of this paper is to deepen this surprising occurrence and to make explicit the relation between the Mess parameters and the embedding data of any Cauchy surface. This relation is pointed out by using some specific properties of Codazzi tensors on hyperbolic surfaces. As a by-product we get a new Lorentzian proof of Goldman's celebrated result about the coincidence of the Weil-Petersson symplectic form and the Goldman pairing. In the second part of the paper we use this machinery to get a classification of globally hyperbolic flat space-times with particles of angles in $(0,2\\pi)$ containing a uniformly convex Cauchy surface. The analogue of Mess' result is achieved showing that the corresponding moduli space is the tangent bundle of the Teichm\\"uller space of a punctured surf...

  8. What Causes Electron Holes During Magnetic Reconnection and What Can We Learn From Them

    Science.gov (United States)

    Goldman, Martin V.; Newman, David L.; Lapenta, Giovanni; Divin, Andre; Califano, Francesco; Che, Haihong

    2009-11-01

    Weak bipolar electrostatic fields are commonly observed in association with magnetic reconnection. Recent attention has focused on their origin due to nonlinear evolution of electrostatic instabilities.footnotetextGoldman, M. V., D. L. Newman, and P. Pritchett, GRL, 35, doi:10.1029/2008GL035608 (2008).^,footnotetextNewman, D. L. and M. V. Goldman, SM31B-1735, AGU Fall Meeting (2008).^,footnotetextChe, H., J. F. Drake, M. Swisdak, and P. H. Yoon, PRL, 102, 145004 (2009). We present evidence from both older and new reconnection simulations for the SPATIAL dependence of electrostatically unstable electron distributions along the separatrix during guide-field magnetic reconection. Particle distributions further from the reconnection region tend to be Buneman (electron-ion) unstable, while distributions closer to the reconnection region tend to be two-stream (electron-electron) unstable. It may be possible to infer properties of the particle distributions from measurements of the speed, half-width, amplitude and aspect ratio of weak electron holes.

  9. Severe unexpected adverse effects after permanent eye makeup and their management by Q-switched Nd:YAG laser

    Directory of Open Access Journals (Sweden)

    Goldman A

    2014-08-01

    Full Text Available Alberto Goldman,1 Uwe Wollina2 1Clinica Goldman, Porto Alegre RS, Brazil; 2Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, Germany Abstract: Permanent makeup is a cosmetic tattoo that is used to enhance one’s appearance, and which has become more popular among middle-aged and elderly women. A couple of benefits seem to be associated with permanent tattoos in the elderly: saving time (wake up with makeup; poor eyesight (difficult to apply makeup; and saving money. On the other hand, cosmetic tattoos bear the same risks as other tattoo procedures. We report on fading and unintended hyperpigmentation after tattooing on eyebrows and eyelids, and discuss the scientific and anatomical background behind the possible cause. Dermatochalasis may be a possible risk factor for excessive unwanted discolorations. Q-switched neodymium-doped yttrium aluminum garnet laser is an appropriate and safe therapeutic tool that can manage such adverse effects. Consumer protection warrants better information and education of the risks of cosmetic tattoos – in particular, for elderly women. Keywords: permanent makeup, cosmetic tattoos, adverse effects, dermatochalasis, Q-switched Nd:YAG laser

  10. Ontologies and standards in bioscience research: for machine or for human

    Directory of Open Access Journals (Sweden)

    Huaiyu eMi

    2011-02-01

    Full Text Available Ontologies and standards are very important parts of today’s bioscience research. With the rapid increase of biological knowledge, they provide mechanisms to better store and represent data in a controlled and structured way, so that scientists can share the data, and utilize a wide variety of software and tools to manage and analyze the data. Most of these standards are initially designed for computers to access large amounts of data that are difficult for human biologists to handle, and it is important to keep in mind that ultimately biologists are going to produce and interpret the data. While ontologies and standards must follow strict semantic rules that may not be familiar to biologists, effort must be spent to lower the learning barrier by involving biologists in the process of development, and by providing software and tool support. A standard will not succeed without support from the wider bioscience research community. Thus, it is crucial that these standards be designed not only for machines to read, but also to be scientifically accurate and intuitive to human biologists.

  11. ModeLang: a new approach for experts-friendly viral infections modeling.

    Science.gov (United States)

    Wasik, Szymon; Prejzendanc, Tomasz; Blazewicz, Jacek

    2013-01-01

    Computational modeling is an important element of systems biology. One of its important applications is modeling complex, dynamical, and biological systems, including viral infections. This type of modeling usually requires close cooperation between biologists and mathematicians. However, such cooperation often faces communication problems because biologists do not have sufficient knowledge to understand mathematical description of the models, and mathematicians do not have sufficient knowledge to define and verify these models. In many areas of systems biology, this problem has already been solved; however, in some of these areas there are still certain problematic aspects. The goal of the presented research was to facilitate this cooperation by designing seminatural formal language for describing viral infection models that will be easy to understand for biologists and easy to use by mathematicians and computer scientists. The ModeLang language was designed in cooperation with biologists and its computer implementation was prepared. Tests proved that it can be successfully used to describe commonly used viral infection models and then to simulate and verify them. As a result, it can make cooperation between biologists and mathematicians modeling viral infections much easier, speeding up computational verification of formulated hypotheses.

  12. ICTR-PHE: scientists engage with multidisciplinary research

    CERN Multimedia

    Antonella Del Rosso

    2015-01-01

    In 2016, the next edition of the unique conference that gathers scientists from a variety of fields will focus on many topics particularly dear to the heart of physicists, clinicians, biologists, and computer specialists. The call for abstracts is open until 16 October.   When detector physicists, radiochemists, nuclear-medicine physicians and other physicists, biologists, software developers, accelerator experts and oncologists think outside the box and get involved in multidisciplinary research, they create innovative healthcare. ICTR-PHE is a biennial event, co-organised by CERN, whose main aim is to foster multidisciplinary research by positioning itself at the crossing of physics, medicine and biology. At the ICTR-PHE conference, physicists, engineers, and computer scientists share their knowledge and technologies while doctors and biologists present their needs and vision for the medical tools of the future, thus triggering breakthrough ideas and technological developments in speci...

  13. Progeria: Translational insights from cell biology

    Science.gov (United States)

    Gordon, Leslie B.; Cao, Kan

    2012-01-01

    Cell biologists love to think outside the box, pursuing many surprising twists and unexpected turns in their quest to unravel the mysteries of how cells work. But can cell biologists think outside the bench? We are certain that they can, and clearly some already do. To encourage more cell biologists to venture into the realm of translational research on a regular basis, we would like to share a handful of the many lessons that we have learned in our effort to develop experimental treatments for Hutchinson-Gilford progeria syndrome (HGPS), an endeavor that many view as a “poster child” for how basic cell biology can be translated to the clinic. PMID:23027899

  14. Bioinspiration: applying mechanical design to experimental biology.

    Science.gov (United States)

    Flammang, Brooke E; Porter, Marianne E

    2011-07-01

    The production of bioinspired and biomimetic constructs has fostered much collaboration between biologists and engineers, although the extent of biological accuracy employed in the designs produced has not always been a priority. Even the exact definitions of "bioinspired" and "biomimetic" differ among biologists, engineers, and industrial designers, leading to confusion regarding the level of integration and replication of biological principles and physiology. By any name, biologically-inspired mechanical constructs have become an increasingly important research tool in experimental biology, offering the opportunity to focus research by creating model organisms that can be easily manipulated to fill a desired parameter space of structural and functional repertoires. Innovative researchers with both biological and engineering backgrounds have found ways to use bioinspired models to explore the biomechanics of organisms from all kingdoms to answer a variety of different questions. Bringing together these biologists and engineers will hopefully result in an open discourse of techniques and fruitful collaborations for experimental and industrial endeavors.

  15. Organic Chemistry and Biology: Chemical Biology Through the Eyes of Collaboration

    Science.gov (United States)

    Hruby, Victor J.

    2011-01-01

    From a scientific perspective, efforts to understand biology including what constitutes health and disease has become a chemical problem. However, chemists and biologists “see” the problems of understanding biology from different perspectives, and this has retarded progress in solving the problems especially as they relate to health and disease. This suggests that close collaboration between chemists and biologists is not only necessary but essential for progress in both the biology and chemistry that will provide solutions to the global questions of biology. This perspective has directed my scientific efforts for the past 45 years, and in this overview I provide my perspective of how the applications of synthetic chemistry, structural design, and numerous other chemical principles have intersected in my collaborations with biologists to provide new tools, new science, and new insights that were only made possible and fruitful by these collaborations. PMID:20000552

  16. Using Apollo to browse and edit genome annotations.

    Science.gov (United States)

    Misra, Sima; Harris, Nomi

    2006-01-01

    An annotation is any feature that can be tied to genomic sequence, such as an exon, transcript, promoter, or transposable element. As biological knowledge increases, annotations of different types need to be added and modified, and links to other sources of information need to be incorporated, to allow biologists to easily access all of the available sequence analysis data and design appropriate experiments. The Apollo genome browser and editor offers biologists these capabilities. Apollo can display many different types of computational evidence, such as alignments and similarities based on BLAST searches (UNITS 3.3 & 3.4), and enables biologists to utilize computational evidence to create and edit gene models and other genomic features, e.g., using experimental evidence to refine exon-intron structures predicted by gene prediction algorithms. This protocol describes simple ways to browse genome annotation data, as well as techniques for editing annotations and loading data from different sources.

  17. Organic chemistry and biology: chemical biology through the eyes of collaboration.

    Science.gov (United States)

    Hruby, Victor J

    2009-12-18

    From a scientific perspective, efforts to understand biology including what constitutes health and disease has become a chemical problem. However, chemists and biologists "see" the problems of understanding biology from different perspectives, and this has retarded progress in solving the problems especially as they relate to health and disease. This suggests that close collaboration between chemists and biologists is not only necessary but essential for progress in both the biology and chemistry that will provide solutions to the global questions of biology. This perspective has directed my scientific efforts for the past 45 years, and in this overview I provide my perspective of how the applications of synthetic chemistry, structural design, and numerous other chemical principles have intersected in my collaborations with biologists to provide new tools, new science, and new insights that were only made possible and fruitful by these collaborations.

  18. Learning in Plants: Lessons from Mimosa pudica

    Directory of Open Access Journals (Sweden)

    Charles Ira Abramson

    2016-03-01

    Full Text Available This article provides an overview of the early Mimosa pudica literature; much of which is in journals not easily accessible to the reader. In contrast to the contemporary plant learning literature which is conducted primarily by plant biologists, this early literature was conducted by comparative psychologists whose goal was to search for the generality of learning phenomena such as habituation, and classical conditioning using experimental designs based on animal conditioning studies. In addition to reviewing the early literature, we hope to encourage collaborations between plant biologists and comparative psychologists by familiarizing the reader with issues in the study of learning faced by those working with animals. These issues include no consistent definition of learning phenomena and an overreliance on the use of cognition. We suggested that greater collaborative efforts be made between plant biologists and comparative psychologists if the study of plant learning is to be fully intergraded into the mainstream behavior theory.

  19. Basic statistics in cell biology.

    Science.gov (United States)

    Vaux, David L

    2014-01-01

    The physicist Ernest Rutherford said, "If your experiment needs statistics, you ought to have done a better experiment." Although this aphorism remains true for much of today's research in cell biology, a basic understanding of statistics can be useful to cell biologists to help in monitoring the conduct of their experiments, in interpreting the results, in presenting them in publications, and when critically evaluating research by others. However, training in statistics is often focused on the sophisticated needs of clinical researchers, psychologists, and epidemiologists, whose conclusions depend wholly on statistics, rather than the practical needs of cell biologists, whose experiments often provide evidence that is not statistical in nature. This review describes some of the basic statistical principles that may be of use to experimental biologists, but it does not cover the sophisticated statistics needed for papers that contain evidence of no other kind.

  20. WE-G-213-01: Roentgen and the Birth of Modern Medical Physics

    Energy Technology Data Exchange (ETDEWEB)

    Sprawls, P. [Sprawls Educational Foundation (United States)

    2015-06-15

    Roentgen and the Birth of Modern Medical Physics – Perry Sprawls Wilhelm Roentgen is well known for his discovery of x-radiation. What is less known and appreciated is his intensive research following the discovery to determine the characteristics of the “new kind of radiation” and demonstrate its great value for medical purposes. In this presentation we will imagine ourselves in Roentgen’s mind and follow his thinking, including questions and doubts, as he designs and conducts a series of innovative experiments that provided the foundation for the rapid growth of medical physics. Learning Objectives: Become familiar with the personal characteristics and work of Prof. Roentgen that establishes him as an inspiring model for the medical physics profession. Observe the thought process and experiments that determined and demonstrated the comprehensive characteristics of x-radiation. The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who were they and what did they do? – Lawrence N. Rothenberg William David Coolidge (1873–1975) William Coolidge was born in Hudson, NY in 1873. He obtained his BS at the Massacusetts Institute of Technology in 1896. Coolidge then went to the University of Leipzig, Germany for graduate study with physicists Paul Drude and Gustave Wiedemann and received a Ph.D. in 1899. While in Germany he met Wilhelm Roentgen. Coolidge returned to the US to teach at MIT where he was associated with Arthur A. Noyes of the Chemistry Department, working on the electrical conductivity of aqueous solutions. Willis R. Whitney, under whom Coolidge had worked before going to Germany, became head of the newly formed General Electric Research Laboratory and he invited Coolidge to work with him. In 1905, Coolidge joined the staff of the GE laboratory and was associated with it for the remainder of his life. He developed ductile tungsten filaments to replace fragile carbon filaments as the material for electric light

  1. The art of editing RNA structural alignments

    DEFF Research Database (Denmark)

    Andersen, Ebbe Sloth

    2014-01-01

    Manual editing of RNA structural alignments may be considered more art than science, since it still requires an expert biologist to take multiple levels of information into account and be slightly creative when constructing high-quality alignments. Even though the task is rather tedious, it is re......Manual editing of RNA structural alignments may be considered more art than science, since it still requires an expert biologist to take multiple levels of information into account and be slightly creative when constructing high-quality alignments. Even though the task is rather tedious...

  2. Pixel Perfect: a real-time image processing system for biology

    Energy Technology Data Exchange (ETDEWEB)

    Perrine, Kenneth A.; Hopkins, Derek F.; Lamarche, Brian L.; Budge, Scott E.; Sowa, Marianne B.

    2005-09-16

    Scientific visioning systems often rely upon pixel-perfect precision to produce meaningful data. Cutting-edge equipment used in the study of cell signaling is no exception; proper image alignment is critical for successful experiments. Biologists at Pacific Northwest National Laboratory put together a special multi-spectral confocal microscope that was capable of producing live images of cells and proteins in two simultaneous spectral channels. But there was a problem: the dual images resembled poorly registered Sunday comics and were unusable. This article describes how the biologists worked with programmers to fix the difficulty and make the microscope a truly useful and unique device.

  3. A fisheye viewer for microarray-based gene expression data

    OpenAIRE

    2006-01-01

    Abstract Background Microarray has been widely used to measure the relative amounts of every mRNA transcript from the genome in a single scan. Biologists have been accustomed to reading their experimental data directly from tables. However, microarray data are quite large and are stored in a series of files in a machine-readable format, so direct reading of the full data set is not feasible. The challenge is to design a user interface that allows biologists to usefully view large tables of ra...

  4. Statistics for proteomics: experimental design and 2-DE differential analysis.

    Science.gov (United States)

    Chich, Jean-François; David, Olivier; Villers, Fanny; Schaeffer, Brigitte; Lutomski, Didier; Huet, Sylvie

    2007-04-15

    Proteomics relies on the separation of complex protein mixtures using bidimensional electrophoresis. This approach is largely used to detect the expression variations of proteins prepared from two or more samples. Recently, attention was drawn on the reliability of the results published in literature. Among the critical points identified were experimental design, differential analysis and the problem of missing data, all problems where statistics can be of help. Using examples and terms understandable by biologists, we describe how a collaboration between biologists and statisticians can improve reliability of results and confidence in conclusions.

  5. Structural proteins of the primary cell wall: extraction, purification, and analysis.

    Science.gov (United States)

    Lamport, Derek T A; Tan, Li; Kieliszewski, Marcia J

    2011-01-01

    Structural proteins of the primary cell wall present unusual but interesting problems for structural biologists in particular and plant biologists in general. As structure is the key to function; then the biochemical isolation of these glycoproteins for further study is paramount. Here, we detail the "classical" method for isolating soluble extensin monomers by elution of monomeric precursors to network extensin from tissue cultures. We also outline an additional approach involving genetic engineering that can potentially yield the complete genomic range of extensins and other hydroxyproline-rich glycoprotein (HRGPs) currently underutilized for biotechnology.

  6. BEST-PRACTICE GUIDELINES FOR FIELD-BASED SURGERY AND ANESTHESIA ON FREE-RANGING WILDLIFE. II. SURGERY.

    Science.gov (United States)

    Fiorello, Christine V; Harms, Craig A; Chinnadurai, Sathya K; Strahl-Heldreth, Danielle

    2016-04-01

    The principles of surgical asepsis apply to field surgeries with few exceptions. The minimum level for performance of surgeries in the field on free-ranging animals should be the same as for domestic animals undergoing surgery in animal hospitals. Surgeries in the field are typically done as part of research and management projects and usually involve a combination of biologists and veterinarians with the possibility of conflicts in scientific cultures. This article outlines a minimum standard of care for field surgeries and will serve as a resource for Institutional Animal Care and Use Committees and biologists and veterinarians planning projects that involve surgeries on free-ranging wildlife in field conditions.

  7. The Low Down on e-Science and Grids for Biology

    Directory of Open Access Journals (Sweden)

    Carole Goble

    2006-04-01

    Full Text Available The Grid is touted as a next generation Internet/Web, designed primarily to support e-Science. I hope to shed some light on what the Grid is, its purpose, and its potential impact on scientific practice in biology. The key message is that biologists are already primarily working in a manner that the Grid is intended to support. However, to ensure that the Grid’s good intentions are appropriate and fulfilled in practice, biologists must become engaged in the process of its development.

  8. The Low Down on e-Science and Grids for Biology

    OpenAIRE

    Carole Goble

    2001-01-01

    The Grid is touted as a next generation Internet/Web, designed primarily to support e-Science. I hope to shed some light on what the Grid is, its purpose, and its potential impact on scientific practice in biology. The key message is that biologists are already primarily working in a manner that the Grid is intended to support. However, to ensure that the Grid’s good intentions are appropriate and fulfilled in practice, biologists must become engaged in the process of its development....

  9. Physarum Can Compute Shortest Paths

    CERN Document Server

    Bonifaci, Vincenzo; Varma, Girish

    2011-01-01

    A mathematical model has been proposed by biologists to describe the feedback mechanism used by the Physarum Polycephalum slime mold to adapt its tubular channels while foraging two food sources $s_0$ and $s_1$. We give a proof of the fact that, under this model, the mass of the mold will eventually converge to the shortest $s_0$-$s_1$ path of the network that the mold lies on, independently of the structure of the network or of the initial mass distribution. This matches the experimental observations by the biologists and can be seen as an example of a "natural algorithm", that is, an algorithm developed by evolution over millions of years.

  10. Flow cytometry: retrospective, fundamentals and recent instrumentation.

    Science.gov (United States)

    Picot, Julien; Guerin, Coralie L; Le Van Kim, Caroline; Boulanger, Chantal M

    2012-03-01

    Flow cytometry is a complete technology given to biologists to study cellular populations with high precision. This technology elegantly combines sample dimension, data acquisition speed, precision and measurement multiplicity. Beyond the statistical aspect, flow cytometry offers the possibility to physically separate sub-populations. These performances come from the common endeavor of physicists, biophysicists, biologists and computer engineers, who succeeded, by providing new concepts, to bring flow cytometry to current maturity. The aim of this paper is to present a complete retrospective of the technique and remind flow cytometry fundamentals before focusing on recent commercial instrumentation.

  11. Biological and Pharmaceutical Nanomaterials

    Science.gov (United States)

    Kumar, Challa S. S. R.

    2006-01-01

    This first comprehensive yet concise overview of all important classes of biological and pharmaceutical nanomaterials presents in one volume the different kinds of natural biological compounds that form nanomaterials or that may be used to purposefully create them. This unique single source of information brings together the many articles published in specialized journals, which often remain unseen by members of other, related disciplines. Covering pharmaceutical, nucleic acid, peptide and DNA-Chitosan nanoparticles, the book focuses on those innovative materials and technologies needed for the continued growth of medicine, healthcare, pharmaceuticals and human wellness. For chemists, biochemists, cell biologists, materials scientists, biologists, and those working in the pharmaceutical and chemical industries.

  12. Planar cell polarity, ciliogenesis and neural tube defects.

    Science.gov (United States)

    Wallingford, John B

    2006-10-15

    Cilia are microtubule-based protrusions that are found on the surface of most vertebrate cells. Long studied by cell biologists, these organelles have recently caught the attention of developmental biologists and human geneticists. In this review, I will discuss recent findings suggesting a link between cilia and the planar cell polarity signaling cascade. In particular, I will focus on how this interaction may influence the process of neural tube closure and how these results may be relevant to our understanding of common human birth defects in which neural tube closure is compromised.

  13. Importing the homology concept from biology into developmental psychology.

    Science.gov (United States)

    Moore, David S

    2013-01-01

    To help introduce the idea of homology into developmental psychology, this article presents some of the concepts, distinctions, and guidelines biologists and philosophers of biology have devised to study homology. Some unresolved issues related to this idea are considered as well. Because homology reflects continuity across time, developmental scientists should find this concept to be useful in the study of psychological/behavioral development, just as biologists have found it essential in the study of the evolution and development of morphological and other characteristics.

  14. Extracellular potassium inhibits Kv7.1 potassium channels by stabilizing an inactivated state

    DEFF Research Database (Denmark)

    Larsen, Anders Peter; Steffensen, Annette Buur; Grunnet, Morten;

    2011-01-01

    Kv7.1 (KCNQ1) channels are regulators of several physiological processes including vasodilatation, repolarization of cardiomyocytes, and control of secretory processes. A number of Kv7.1 pore mutants are sensitive to extracellular potassium. We hypothesized that extracellular potassium also...... modulates wild-type Kv7.1 channels. The Kv7.1 currents were measured in Xenopus laevis oocytes at different concentrations of extracellular potassium (1-50 mM). As extracellular potassium was elevated, Kv7.1 currents were reduced significantly more than expected from theoretical calculations based...... on the Goldman-Hodgkin-Katz flux equation. Potassium inhibited the steady-state current with an IC(50) of 6.0 ± 0.2 mM. Analysis of tail-currents showed that potassium increased the fraction of channels in the inactivated state. Similarly, the recovery from inactivation was slowed by potassium, suggesting...

  15. Knowledge, Belief, and Science Education - A Contribution from the Epistemology of Testimony

    Science.gov (United States)

    Ferreira, Tiago Alfredo S.; El-Hani, Charbel N.; da Silva-Filho, Waldomiro José

    2016-07-01

    This article intends to show that the defense of "understanding" as one of the major goals of science education can be grounded on an anti-reductionist perspective on testimony as a source of knowledge. To do so, we critically revisit the discussion between Harvey Siegel and Alvin Goldman about the goals of science education, especially where it involves arguments based on the epistemology of testimony. Subsequently, we come back to a discussion between Charbel N. El-Hani and Eduardo Mortimer, on the one hand, and Michael Hoffmann, on the other, striving to strengthen the claim that rather than students' belief change, understanding should have epistemic priority as a goal of science education. Based on these two lines of discussion, we conclude that the reliance on testimony as a source of knowledge is necessary to the development of a more large and comprehensive scientific understanding by science students.

  16. Counterfactual reasoning for regretted situations involving controllable versus uncontrollable events: the modulating role of contingent self-esteem.

    Science.gov (United States)

    Wilkinson, Meredith R; Ball, Linden J; Alford, David

    2015-01-01

    We report a study that examined the modulating impact of contingent self-esteem on regret intensity for regretted outcomes associated with controllable versus uncontrollable events. The Contingent Self-Esteem Scale (e.g., Kernis & Goldman, 2006) was used to assess the extent to which a person's sense of self-worth is based on self and others' expectations. We found that there was an influence of self-esteem contingency for controllable but not for uncontrollable regret types. For controllable regret types individuals with a high contingent (i.e., unstable) self-esteem reported greater regret intensity than those with a low contingent (i.e., stable) self-esteem. We interpret this finding as reflecting a functional and adaptive role of high contingent self-esteem in terms of mobilizing the application of counterfactual reasoning and planning mechanisms that can enable personal expectations to be achieved in the future.

  17. A century of endodontics: from Philadelphia to Boston.

    Science.gov (United States)

    Millstein, Charles B

    2010-01-01

    While Dr. Grossman was in Rostock with a letter of introduction from Dr. Prinz, he visited several distinguished dentists in Berlin. One was the aged Dr. Otto Walkoff, who, with the help of a physicist while in Wurzberg, was the first dentist to capture the image of a tooth soon after the discovery of radiology by Roentgen in 1895. At his home, Dr. Walkoff passed the X-ray tube head that had taken the historic film to Dr. Grossman, who then held this treasured artifact in his hands. This transfer of culture from Germany to the United States marked the beginning of modern endodontics. Similarly, when Dr. Goldman gave Dr. Schilder his backing by sending him to study under Dr. Grossman at the University of Pennsylvania, the progress of endodontic excellence moved forward, ensuring a Century of Endodontics.

  18. A new species of nectar-feeding bat, genus Lonchophylla, from western Colombia and western Ecuador (Mammalia: Chiroptera: Phyllostomidae)

    Science.gov (United States)

    Woodman, N.

    2007-01-01

    The twelve recognized species of nectar-feeding bats of the genus Lonchophylla occur in low- and middle-elevation, humid, Neotropical forests. Morphological and morphometrical analyses of specimens formerly lumped with Lonchophylla mordax O. Thomas (1903) support recognition of Lonchophylla concava Goldman (1914) as a separate species and reveal a third species from the western Pacific lowlands of Colombia and Ecuador that I describe herein as Lonchophylla jornicata. This new species is morphologically similar to Lonchophylla concava but is distinctively larger than that species. Tests for sexual dimorphism within these and other species of Lonchophyllini suggest a tendency for females to have slightly longer, narrower skulls, higher coronoid processes of the mandible, and longer forearms than males.

  19. MYERS, Jorge (org.). El siglo XIX de Tulio Halperin Donghi (Dossiê), p.157-238.

    OpenAIRE

    2012-01-01

    Sob o pretexto de comemorar o duplo aniversário dos livros O pensamento de Echeverría (1951) e Tradição política espanhola e ideologia revolucionária da Mayo (1961), Prismas reuniu um grupo de especialistas para refletir sobre as várias obras em que Tulio Halperin Donghi nos ofereceu suas hipóteses sobre o século XIX. Assim, Elías Palti e Noemí Goldman escrevem sobre Tradição política espanhola e ideologia revolucionária da Mayo; Fernando Devoto, José Rilla, Marcela Ternavasio e Gabriel Entín...

  20. My Life as a Quant: Reflections on Physics and Finance

    Science.gov (United States)

    Derman, Emanuel

    2004-09-01

    Emanuel Derman was one of the first physicists to move to Wall Street, and his career paralleled the growth of quantitative trading over the past twenty years. In My Life as a Quant, he traces his transformation from ambitious young scientist to managing director and head of the renowned Quantitative Strategies group at Goldman, Sachs & Co. Derman's tale recounts his adventures with quants, traders and other high fliers on Wall Street as he became the best-known quant in the business. He describes the struggles of research and his interactions with an assorted cast of famous scientists. He relates his impressions of some of the most creative minds on Wall Street, including Fischer Black, with whom he collaborated on the widely used Black-Derman-Toy model of interest rates. Throughout his story he reflects on the appropriate way to apply the refined methods of physics to the hurly-burly world of markets and the people that inhabit them.

  1. Theory and Inference for a Class of Observation-driven Models with Application to Time Series of Counts

    CERN Document Server

    Davis, Richard A

    2012-01-01

    This paper studies theory and inference related to a class of time series models that incorporates nonlinear dynamics. It is assumed that the observations follow a one-parameter exponential family of distributions given an accompanying process that evolves as a function of lagged observations. We employ an iterated random function approach and a special coupling technique to show that, under suitable conditions on the parameter space, the conditional mean process is a geometric moment contracting Markov chain and that the observation process is absolutely regular with geometrically decaying coefficients. Moreover the asymptotic theory of the maximum likelihood estimates of the parameters is established under some mild assumptions. These models are applied to two examples; the first is the number of transactions per minute of Ericsson stock and the second is related to return times of extreme events of Goldman Sachs Group stock.

  2. Application of the Postconcussive Syndrome Questionnaire with medical and psychiatric outpatients.

    Science.gov (United States)

    Axelrod, B N; Fox, D D; Lees-Haley, P R; Earnest, K; Dolezal-Wood, S

    1998-08-01

    The Postconcussive Syndrome Questionnaire (PCSQ; Lees-Haley, 1992) was previously found (Axelrod, Fox, Lees-Haley, Earnest, Dolezal-Wood, & Goldman, 1996) to produce four factors, named Psychological, Somatic, Cognitive, and Infrequency. These four factors of the questionnaire were evaluated across five groups of medical and psychiatric outpatients. The patients were from neurology, mental health, family practice, and internal medicine clinics as well as from a clinic that evaluated new patients to a health maintenance organization. Mental health patients had greater psychological symptoms and fewer health concerns than the other groups. Neurology patients differed from the other groups by having greater Infrequency symptoms. Patients who were referred for their screening evaluation or were seen by internal medicine had fewer overall symptoms than the other three patient groups. The data from this study provide support for the use of the PCSQ as a multifactorial self-report measure of symptom presentation.

  3. Sand swimming lizard: sandfish

    CERN Document Server

    Maladen, Ryan D; Kamor, Adam; Goldman, Daniel I

    2009-01-01

    We use high-speed x-ray imaging to reveal how a small (~10cm) desert dwelling lizard, the sandfish (Scincus scincus), swims within a granular medium [1]. On the surface, the lizard uses a standard diagonal gait, but once below the surface, the organism no longer uses limbs for propulsion. Instead it propagates a large amplitude single period sinusoidal traveling wave down its body and tail to propel itself at speeds up to ~1.5 body-length/sec. Motivated by these experiments we study a numerical model of the sandfish as it swims within a validated soft sphere Molecular Dynamics granular media simulation. We use this model as a tool to understand dynamics like flow fields and forces generated as the animal swims within the granular media. [1] Maladen, R.D. and Ding, Y. and Li, C. and Goldman, D.I., Undulatory Swimming in Sand: Subsurface Locomotion of the Sandfish Lizard, Science, 325, 314, 2009

  4. Clinical and electrophysiological recovery in Leber hereditary optic neuropathy with G3460A mutation.

    Science.gov (United States)

    Sharkawi, Eamon; Oleszczuk, Justyna D; Holder, Graham E; Raina, Joyti

    2012-08-01

    To report a case of clinical and electrophysiological recovery in Leber hereditary optic neuropathy (LHON) with G3460A Mutation. A 10-year-old boy with a three-month history of painless bilateral sequential visual loss upon presentation underwent visual acuity (diminished), anterior and posterior segment examination (normal), fluorescein angiography (normal), Goldman kinetic perimetry (bilateral central scotomata), genetic (a point G3460A mutation) and electrophysiological investigation (undetectable pattern visual evoked potentials (VEP); low amplitude, broadened and reduced flash VEPs and loss of the N95 component in the pattern electroretinograms). Diagnosis of LHON was made. Eighteen months later vision and electrophysiological tests results began spontaneously improving. Kinetic perimetry revealed reduced density and size of scotomata. Two years later, there had been further electrophysiological improvement. This report describes both clinical and electrophysiological improvement in LHON with G3460A mutation.

  5. Electronic control of H+ current in a bioprotonic device with Gramicidin A and Alamethicin

    Science.gov (United States)

    Hemmatian, Zahra; Keene, Scott; Josberger, Erik; Miyake, Takeo; Arboleda, Carina; Soto-Rodríguez, Jessica; Baneyx, François; Rolandi, Marco

    2016-10-01

    In biological systems, intercellular communication is mediated by membrane proteins and ion channels that regulate traffic of ions and small molecules across cell membranes. A bioelectronic device with ion channels that control ionic flow across a supported lipid bilayer (SLB) should therefore be ideal for interfacing with biological systems. Here, we demonstrate a biotic-abiotic bioprotonic device with Pd contacts that regulates proton (H+) flow across an SLB incorporating the ion channels Gramicidin A (gA) and Alamethicin (ALM). We model the device characteristics using the Goldman-Hodgkin-Katz (GHK) solution to the Nernst-Planck equation for transport across the membrane. We derive the permeability for an SLB integrating gA and ALM and demonstrate pH control as a function of applied voltage and membrane permeability. This work opens the door to integrating more complex H+ channels at the Pd contact interface to produce responsive biotic-abiotic devices with increased functionality.

  6. 中国经济能否续写传奇?

    Institute of Scientific and Technical Information of China (English)

    吉迪恩·拉赫曼

    2009-01-01

    【英国《金融时报》12月25日】在雷曼兄弟公司(Lehman Brothers)倒闭后的几周,中国政府中明显能感觉到一丝最终获胜的得意。中国官员们公开推测,借钱给美国人、让他们为行将就木的银行纾困是否明智。中国对美国的肆意挥霍发出了不满的啧啧声。有人重新提到了高盛(Goldman Sachs)有关中国经济规模将在2027年前超过美国的著名预测——或许这一预测会提前变为现实?

  7. China's Soybean Imports Will Be Decreased 2009

    Institute of Scientific and Technical Information of China (English)

    Deng Ruihong

    2008-01-01

    @@ In September 2008, Lehman Brothers' bankruptcy set off a global financial "tsunami ', with the five major U.S. investment banks fell one after another: Bear Stearns closed down as early as in March, Lehman s bankruptcy, Merrill Lynch being acquired, Goldman Sachs and Morgan Stanley restructuring of commercial banks; the process of United States' "nationalization" was forced to speed up, with Fannie Mae, Freddie Mac and the American International Group (AIG) being taken over by the government; bank insolvency and reorganization were in gradual escalation, with Washington Mutual Bank declaring bankruptcy and Wells Fargo purchasing Wachovia; starting in October, for more than a month's time, global stock market encountered a rare crash, with the major stock indexes such as Dow Jones, Nikkei and European indexes fell more than 20%.

  8. 告别五大投行时代

    Institute of Scientific and Technical Information of China (English)

    Melanie(编译)

    2008-01-01

    拥有85年历史的华尔街第五大投行贝尔斯登(Bear Stearns Cos)贱价出售给摩根大通(JP Morgan Chase& Co);拥有94年历史的美林(MerrillLynch)被综合银行美国银行(BankofAmerica)收购;历史最悠久的投行——158年历史的雷曼(Lehman Brothers)宣布破产;139年的高盛(Goldman Sachs)和73年的摩根士丹利(Morgan Stanley)同时改旗易帜转为银行控股公司。

  9. 华尔街投资银行家:明星中的明星

    Institute of Scientific and Technical Information of China (English)

    拓远

    2002-01-01

    美国投资银行业基本上是一个金字塔结构,位于塔尖的大约有五到十家著名公司,被称作“蓝筹”公司或“塔尖”公司。长期以来占据塔尖位置的公司,享有巨大的品牌优势,闻名遐迩,例如:美林(Merrill Lynch),高盛(Goldman Sachs)、摩根·斯坦利(Morgan Stanley),雷曼兄弟(Lehman Brothers),所罗门美邦(Solomon Smith Barney)。

  10. 走出全球发展危机

    Institute of Scientific and Technical Information of China (English)

    詹斯·马腾斯

    2010-01-01

    @@ 危机没有解除--没有失业和环境可持续性方面的全球伙伴关系,危机就不会解除. 在发达国家,全球经济和金融危机似乎都结束了;20国集团的财长们已在探讨各种退出战略;诸如高盛(Goldman Sachs)和德意志银行(Deutsche Bank)等主要国际银行也开始享有一季度总计数十亿的收益;国际金融市场上的对冲基金(hedge funds)比以前更加活跃,彷佛从未发生过危机似的.

  11. Corn Stocks Plunge as China Adds Brazil-Sized Crop to Usage

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    @@Even a fifth consecutive year of record global corn harvests will fail to meet demand for food, fuel and livestock feed, reducing world stockpiles to the low est in two generations. Consumption will rise 3 percent in the next marketing year, a 16th consecutive annual gain that saw demand jump 66 percent, according to U.S.Department of Agriculture estimates.Inventory will drop to 47 days of use, the fewest since 1974, the data show.Waterlogged fields in the U.S., the largest exporter, will curb yields, Goldman Sachs Group Inc.says.Corn may jump 36 percent to a record US$9 a bushel if conditions worsen, Morgan Stanley says.

  12. Knowledge, Belief, and Science Education

    Science.gov (United States)

    Ferreira, Tiago Alfredo S.; El-Hani, Charbel N.; da Silva-Filho, Waldomiro José

    2016-10-01

    This article intends to show that the defense of "understanding" as one of the major goals of science education can be grounded on an anti-reductionist perspective on testimony as a source of knowledge. To do so, we critically revisit the discussion between Harvey Siegel and Alvin Goldman about the goals of science education, especially where it involves arguments based on the epistemology of testimony. Subsequently, we come back to a discussion between Charbel N. El-Hani and Eduardo Mortimer, on the one hand, and Michael Hoffmann, on the other, striving to strengthen the claim that rather than students' belief change, understanding should have epistemic priority as a goal of science education. Based on these two lines of discussion, we conclude that the reliance on testimony as a source of knowledge is necessary to the development of a more large and comprehensive scientific understanding by science students.

  13. Time to Open the BRIC Door

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    MUCH has been said about South Africa joining the BRIC.Detractors say that the country is punching way above its weight. One of the biggest critics of the inclusion has been Jim O’Neill,Chairperson of Goldman Sachs Asset Management,who originally coined the term BRIC in 2001. O’Neill is on record as saying that he believes South Africa was invited for political reasons and not economical ones.He says South Africa’s working population is too small,and therefore had plumped for Nigeria to be a better choice to join the BRIC.South Africa’s total population is 50 million with Nigeria triple that at 150 million.

  14. Wireless Josephson Junction Arrays

    Science.gov (United States)

    Adams, Laura

    2015-03-01

    We report low temperature, microwave transmission measurements on a wireless two- dimensional network of Josephson junction arrays composed of superconductor-insulator -superconductor tunnel junctions. Unlike their biased counterparts, by removing all electrical contacts to the arrays and superfluous microwave components and interconnects in the transmission line, we observe new collective behavior in the transmission spectra. In particular we will show emergent behavior that systematically responds to changes in microwave power at fixed temperature. Likewise we will show the dynamic and collective response of the arrays while tuning the temperature at fixed microwave power. We discuss these spectra in terms of the Berezinskii-Kosterlitz-Thouless phase transition and Shapiro steps. We gratefully acknowledge the support Prof. Steven Anlage at the University of Maryland and Prof. Allen Goldman at the University of Minnesota. Physics and School of Engineering and Applied Sciences.

  15. Disease: H00065 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00065 Alexander disease Alexander disease is a rare, but often fatal neurological ...ult forms. The characteristic neuropathological feature of all forms of Alexander's disease is the presence ...y acidic protein (GFAP) and small stress proteins in astrocytes. Neurodegenerative disease GFAP; glial fibrillary acidic protein (mutation) [HSA:2670] [KO:K05640] thyrotropin releasing hormone [DR:D00176] Disease class: leukodystrophy Affected regtion: midbrain, cerebellum Microscopic lesion: Rosenthal fibers MeSH: D038261 OMIM: 203450 PMID:17498694 Quinlan RA, Brenner M, Goldman JE, Messing A. GFAP and its role in Alexander... R, Gibbon T, Prescott AR, Brenner M, Quinlan RA The Alexander disease-causing gl... M TRH therapy in a patient with juvenile Alexander disease. Brain Dev 28:663-7 (

  16. Motion of cells sedimenting on a solid surface in a laminar shear flow.

    Science.gov (United States)

    Tissot, O; Pierres, A; Foa, C; Delaage, M; Bongrand, P

    1992-01-01

    Cell adhesion often occurs under dynamic conditions, as in flowing blood. A quantitative understanding of this process requires accurate knowledge of the topographical relationships between the cell membrane and potentially adhesive surfaces. This report describes an experimental study made on both the translational and rotational velocities of leukocytes sedimenting of a flat surface under laminar shear flow. The main conclusions are as follows: (a) Cells move close to the wall with constant velocity for several tens of seconds. (b) The numerical values of translational and rotational velocities are inconsistent with Goldman's model of a neutrally buoyant sphere in a laminar shear flow, unless a drag force corresponding to contact friction between cells and the chamber floor is added. The phenomenological friction coefficient was 7.4 millinewton.s/m. (c) Using a modified Goldman's theory, the width of the gap separating cells (6 microns radius) from the chamber floor was estimated at 1.4 micron. (d) It is shown that a high value of the cell-to-substrate gap may be accounted for by the presence of cell surface protrusions of a few micrometer length, in accordance with electron microscope observations performed on the same cell population. (e) In association with previously reported data (Tissot, O., C. Foa, C. Capo, H. Brailly, M. Delaage, and P. Bongrand. 1991. Biocolloids and Biosurfaces. In press), these results are consistent with the possibility that cell-substrate attachment be initiated by the formation of a single molecular bond, which might be considered as the rate limiting step.

  17. G x E: a NIAAA workshop on gene-environment interactions.

    Science.gov (United States)

    Gunzerath, Lorraine; Goldman, David

    2003-03-01

    The National Institute on Alcohol Abuse and Alcoholism (NIAAA) sponsored a May 2002 workshop on gene-environment interaction (G x E) research to identify potential roadblocks to further research and to propose solutions to those roadblocks, to optimize investigative opportunities and multidisciplinary or multi-institution collaborations, and to explore ways that NIAAA can facilitate G x E studies. Sessions included panels on animal models; phenotypes; genetic findings in humans; study designs and analytical methods; and assessment of environmental risk. Key among the identified challenges to progress in G x E research were issues of study design and sampling strategies; logistic and methodological costs and constraints; availability and understanding of data analysis techniques; potential stigmatization of study populations; and organizational/bureaucratic structures that are inadequate to address the unique needs of large-scale, multicenter, longitudinal projects. Participants proposed a series of recommendations to address these issues. Session coordinators included: Gayle Boyd, Kendall Bryant, Page Chiapella, Vivian Faden, David Goldman, and Antonio Noronha. Session participants included: Laura Almasy, Henri Begleiter, Raul Caetano, Bruce Dudek, Mary Dufour, Cindy Ehlers, Mary-Anne Enoch, Joel Gelernter, David Goldman, Bridget Grant, Lorraine Gunzerath, Deborah Hasin, Andrew Heath, Victor Hesselbrock, J. Dee Higley, Shirley Hill, Kerry Jang, Raynard S. Kington, Rick Kittles, George Koob, Kenneth Leonard, Ting-Kai Li, Jeffrey Long, William McBride, Matthew McGue, Kathleen Merikangas, Tamara Phillips, Bernice Porjesz, Carol Prescott, Theodore Reich, John Rice, Richard Rose, Charmaine Royal, Arnold Sameroff, Marc Schuckit, Kenneth Sher, Renee Sieving, Robert Taylor, Michael Windle, and Robert Zucker.

  18. E-evolution : e-commerce spread, bu e-dustrial revolution is on hold

    Energy Technology Data Exchange (ETDEWEB)

    Lunan, D.

    2001-09-03

    Approximately two years ago, e-commerce seemed ready to revolutionize the way the oil and gas industry conducted business. After the dot-com demise, Statistics Canada reported that less than one per cent of resource sector companies were selling goods on the Internet. According to financial industry experts, the energy industry should implement an e-business strategy based on four major concepts. They recommended using the Internet as a procurement source, the idea easiest to implement and with the potential to positively improve the bottom line. The second area recommended was assets acquisition and disposition. Some portals have already targeted this market niche, such as IndigoPool.com, operated by Schlumberger. In addition to assets, the portal offers millions of kilometres of two-dimensional seismic data, as well as three-dimensional and gravity or magnetic surveys. Portals like IndigoPool also feature electronic data rooms, similar to physical data rooms where registered customers can view and analyze all relevant information. A key partner in IndigoPool is Waterhouse and Co., whose responsibility is the handling of bids for various properties in Western Canada. The third aspect recommended by Goldman Sachs in a report, is trading in a number of commodities like natural gas, crude oil and liquids, electricity, etc. The fourth aspect favored by Goldman Sachs is reporting and regulatory filings. The National Energy Board established a phased-in electronic regulatory filing environment in the spring of 2001. The standardization of industry and government information systems is continuing on an international scale. 5 figs.

  19. Etnografia como prática e experiência

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    José Guilherme Cantor Magnani

    2009-12-01

    Full Text Available Este artigo, a partir de alguns usos pouco ortodoxos da etnografia, fora do campo da antropologia, propõe uma discussão sobre a especificidade desse método de pesquisa, com base em pesquisas e reflexões realizadas sobre o tema no Núcleo de Antropologia Urbana da USP (NAU. Tomando como ponto de partida uma citação de Lévi-Strauss, repassa alguns autores - Goldman, Peirano, DaMatta, Favret-Saada, entre outros - para estabelecer parâmetros na busca de traços que considera específicos do fazer etnográfico e assim chega a três considerações principais: etnografia como experiência, como prática e com base numa certa noção de totalidade. O relato de uma etnografia sobre jovens surdos é apresentado para oferecer um suporte empírico àquelas conclusões.Considering some less orthodox uses of ethnography, not belonging to the anthropological field, this article proposes a discussion on the specificities of the ethnographical research method, based on reflections and researches undertaken at the Urban Anthropology Nucleus (NAU. Taking a Lévi-Strauss's quotation as its starting point, it examines the ideas of authors like Goldman, Peirano, Da Matta, Favret-Saada, among others, in order to establish parameters to guide the search for specific features in the ethnographic métier. Such a discussion leads to three considerations: ethnography as experience, as practice, and as based on a certain concept of "totality". The report of an ethnography on deaf young people is included in the article as empirical support to the conclusions.

  20. Discrepâncias clínico-patológicas em pacientes graves com difícil diagnóstico pre-mortem

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    Aline Fusco Fares

    2011-12-01

    Full Text Available INTRODUÇÃO: A importância das autópsias é um tema comum de discussão tanto no Brasil como em todo o mundo, já que pode elucidar as causas de óbito e tem um valor social muito amplo. Entretanto, esta prática vem sendo gradualmente considerada desnecessária, tendo ocorrido um declínio no número de exames post-mortem. OBJETIVOS: Comparar o diagnóstico clínico e patológico em pacientes com difícil diagnóstico pre-mortem. MÉTODOS: Foram analisados todos os casos de autópsias (em um total de 98 de pacientes oriundos de três unidades de terapia intensiva médico-cirúrgicas (total de 78 leitos pertencentes a uma faculdade de medicina, realizadas no período de janeiro de 2003 a dezembro de 2006. Analisamos os diagnósticos clínicos e patológicos segundo os critérios de Goldman. RESULTADOS: Em 49 casos (50% foram encontradas discordâncias classes I e II de Goldman. Por outro lado, apenas 30 (30,6% dos casos tiveram uma concordância completa entre os diagnósticos pre-mortem e post-mortem sendo classificados como classe V. As infecções tiveram uma taxa de concordância significantemente maior do que as doenças cardiovasculares. CONCLUSÃO: Encontramos discrepâncias significantes entre os achados clínicos e patológicos, o que reforça o valor dos exames post-mortem.