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Sample records for biologist don francis

  1. Human radiation studies: Remembering the early years: Oral history of cell biologist Don Francis Petersen, Ph.D., conducted November 29, 1994

    International Nuclear Information System (INIS)

    1995-08-01

    This report is a transcript of an interview of Dr. Don Francis Petersen by representatives of the US DOE Office of Human Radiation Experiments. Dr. Petersen was selected for this interview because of his long research career at Los Alamos and his knowledge of the Atomic Energy Commission's biomedical program. Dr. Petersen did not personally conduct research on human subjects. After a brief biographical sketch Dr. Petersen discusses his remembrances of the early use of radionuclides as biological tracers, aspects of nuclear weapons testing in the 1940's and 1950's including fallout studies, the means by which research projects were approved, use of humans in the whole-body counter, and the Health Division Biomedical responsibilities

  2. Human radiation studies: Remembering the early years: Oral history of cell biologist Don Francis Petersen, Ph.D., conducted November 29, 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-08-01

    This report is a transcript of an interview of Dr. Don Francis Petersen by representatives of the US DOE Office of Human Radiation Experiments. Dr. Petersen was selected for this interview because of his long research career at Los Alamos and his knowledge of the Atomic Energy Commission`s biomedical program. Dr. Petersen did not personally conduct research on human subjects. After a brief biographical sketch Dr. Petersen discusses his remembrances of the early use of radionuclides as biological tracers, aspects of nuclear weapons testing in the 1940`s and 1950`s including fallout studies, the means by which research projects were approved, use of humans in the whole-body counter, and the Health Division Biomedical responsibilities.

  3. Francis Picabia hilislooming

    Index Scriptorium Estoniae

    1998-01-01

    Aastavahetusel Hamburgi teises Deichtorhalles olnud näitusest, kus eksponeeriti Francis Picabia (1879-1953) loomingut alates 1935. aastast. Näitus tutvustas Picabiat kui aktimaalijat, portretisti, fotograafi ja kirjameest

  4. Interviewing Francis Bacon

    OpenAIRE

    Kisters, Sandra

    2012-01-01

    British painter Francis Bacon (1909-1992) was known for the eloquence with which he talked about his art. He was easy to talk to, and was interviewed countless times by numerous critics. However, when studying Bacon's paintings one soon comes across the published interviews with art critic and curator David Sylvester (1924-2001), who interviewed him as many as 18 times between 1962 and 1986. Art historian Sandra Kisters argues that Sylvester's interviews with Bacon are carefully constructed a...

  5. The Francis Crick Institute.

    Science.gov (United States)

    Peters, Keith; Smith, Jim

    2017-04-01

    The Francis Crick Institute Laboratory, opened in 2016, is supported by the Medical Research Council, Cancer Research UK, the Wellcome Trust, and University College London, King's College London and Imperial College London. The emphasis on research training and early independence of gifted scientists in a multidisciplinary environment provides unique opportunities for UK medical science, including clinical and translational research. © Royal College of Physicians 2017. All rights reserved.

  6. Francis Bacon's behavioral psychology.

    Science.gov (United States)

    MacDonald, Paul S

    2007-01-01

    Francis Bacon offers two accounts of the nature and function of the human mind: one is a medical-physical account of the composition and operation of spirits specific to human beings, the other is a behavioral account of the character and activities of individual persons. The medical-physical account is a run-of-the-mill version of the late Renaissance model of elemental constituents and humoral temperaments. The other, less well-known, behavioral account represents an unusual position in early modern philosophy. This theory espouses a form of behavioral psychology according to which (a) supposed mental properties are "hidden forms" best described in dispositional terms, (b) the true character of an individual can be discovered in his observable behavior, and (c) an "informed" understanding of these properties permits the prediction and control of human behavior. Both of Bacon's theories of human nature fall under his general notion of systematic science: his medical-physical theory of vital spirits is theoretical natural philosophy and his behavioral theory of disposition and expression is operative natural philosophy. Because natural philosophy as a whole is "the inquiry of causes and the production of effects," knowledge of human nature falls under the same two-part definition. It is an inquisition of forms that pertains to the patterns of minute motions in the vital spirits and the production of effects that pertains both to the way these hidden motions produce behavioral effects and to the way in which a skillful agent is able to produce desired effects in other persons' behavior. (c) 2007 Wiley Periodicals, Inc.

  7. Francis Crick (1916–2004)

    Indian Academy of Sciences (India)

    Administrator

    The death of Francis Crick deprives us of one of the great- est scientists of the 20th century, whose creativity and power of mind dominated molecular biology in its golden years. Many people have told the story of his achievements; here I would simply like to recollect some of the qualities of this remarkable man. The first ...

  8. Francis Crick (1916–2004)

    Indian Academy of Sciences (India)

    Administrator

    him. When somebody gave a lecture, Francis was ready at the end (and often in the middle) to give them a lucid and exact account of what their work meant, for better or for worse. This made the Laboratory of Molecular Biology's end-of-year lectures a terrifying ordeal for many, but in- creased their intellectual value, and ...

  9. Francis Bacon and Jacobean legitimation

    OpenAIRE

    Rodríguez García, José María

    1997-01-01

    Francis Bacon (1561-1626) maintained a lifelong interest in the institutional implementation of experimental science. What changed over the years were the rhetorical strategies employed to give this project legitimacy. I systematize those changes by dividing Bacon's works into three groups according to three criteria: what rite of officialization is enacted in each text (e.g., conversion, fatherly generation, royal delegation); who the inscribed addressee is (e.g., an imagin...

  10. A Biologist Looks at Cognitive Artificial Intelligence

    OpenAIRE

    Purves, William K.

    1985-01-01

    Although cognitive AI is not generally viewed as being "scientific" in the same, strong sense as is physics, it shares a number of the properties of the natural sciences, especially biology. Certain of special themes of biology, notably the principles of historicity and of structure-function relations, are applicable in AI research. From a biologist's viewpoint, certain principles of cognitive AI research emerge.

  11. Francis Bacon, un moderne intempestif

    OpenAIRE

    Mavrakis, Annie

    2017-01-01

    À propos de la peinture de Francis Bacon et en prenant appui sur des réflexions de Michel Leiris, cet article se propose de revenir sur la question de la modernité conçue non de façon absolue (LA modernité, non figurative, anti-littéraire) mais relative, dégagée d’une vision historiciste orientée de l’histoire de l’art. Cette modernité est intempestive puisque, s’opposant au classique (cf. La Querelle des Anciens et des Modernes) et non au périmé, elle fait revivre les grandes problématiques ...

  12. PURSUING AN EXCITING CAREER AS A WILDLIFE BIOLOGIST

    Science.gov (United States)

    Many people associate a career as a biologist to be similar to TV stars such as Jeff Corwin. Although biologists get to do exciting things like what viewers see on TV, being a biologist involves much more. I will talk about my career as a biologist, discuss experiences that you...

  13. Francis Bacon and the Technology of Style.

    Science.gov (United States)

    Baker, Christopher

    1983-01-01

    Examines Francis Bacon's intentionally devised style for scientific writings and the theoretical basis of that style. Discusses his emphasis on a truly objective point of view, and his use of aphorisms to adapt to his audience. (HTH)

  14. Francis Crick, DNA, and the Central Dogma

    Science.gov (United States)

    Olby, Robert

    1970-01-01

    This essay describes how Francis Crick, ex-physicist, entered the field of biology and discovered the structure of DNA. Emphasis is upon the double helix, the sequence hypothesis, the central dogma, and the genetic code. (VW)

  15. Francis Bacon and Magnetical Cosmology.

    Science.gov (United States)

    Wang, Xiaona

    2016-12-01

    A short-lived but important movement in seventeenth-century English natural philosophy—which scholars call “magnetical philosophy” or “magnetical cosmology”—sought to understand gravity (both terrestrial and celestial) by analogy with magnetism. The movement was clearly inspired by William Gilbert’s De magnete (1600) and culminated with Robert Hooke’s prefiguring of the universal principle of gravitation, which he personally communicated to Isaac Newton in 1679. But the magnetical cosmology, as professed by those in the movement, differed from Gilbert’s philosophy in highly significant ways. Proponents never accepted Gilbert’s animistic account of magnets and seem tacitly to have accepted a belief in action at a distance that Gilbert himself rejected. This essay argues that Francis Bacon (1561–1626) had already provided just the adaptations to Gilbert’s philosophy that the later thinkers adopted, including an important endorsement of action at a distance, and that he should be recognized as playing an important role in the movement.

  16. Which statistics should tropical biologists learn?

    Science.gov (United States)

    Loaiza Velásquez, Natalia; González Lutz, María Isabel; Monge-Nájera, Julián

    2011-09-01

    Tropical biologists study the richest and most endangered biodiversity in the planet, and in these times of climate change and mega-extinctions, the need for efficient, good quality research is more pressing than in the past. However, the statistical component in research published by tropical authors sometimes suffers from poor quality in data collection; mediocre or bad experimental design and a rigid and outdated view of data analysis. To suggest improvements in their statistical education, we listed all the statistical tests and other quantitative analyses used in two leading tropical journals, the Revista de Biología Tropical and Biotropica, during a year. The 12 most frequent tests in the articles were: Analysis of Variance (ANOVA), Chi-Square Test, Student's T Test, Linear Regression, Pearson's Correlation Coefficient, Mann-Whitney U Test, Kruskal-Wallis Test, Shannon's Diversity Index, Tukey's Test, Cluster Analysis, Spearman's Rank Correlation Test and Principal Component Analysis. We conclude that statistical education for tropical biologists must abandon the old syllabus based on the mathematical side of statistics and concentrate on the correct selection of these and other procedures and tests, on their biological interpretation and on the use of reliable and friendly freeware. We think that their time will be better spent understanding and protecting tropical ecosystems than trying to learn the mathematical foundations of statistics: in most cases, a well designed one-semester course should be enough for their basic requirements.

  17. Poetic and Francis Bacon's Ambivalence toward Language.

    Science.gov (United States)

    Pribble, Paula Tompkins

    Just as rhetoric is a way of knowing, so is poetic, both of which, for Francis Bacon, produce false knowledge. But Bacon is not entirely negative. When the poetic elements of language are used in strategic and public communication, like the scholarly communication Bacon attempts to reform, poetic and rhetoric work together to create a plurality of…

  18. Which statistics should tropical biologists learn?

    Directory of Open Access Journals (Sweden)

    Natalia Loaiza Velásquez

    2011-09-01

    Full Text Available Tropical biologists study the richest and most endangered biodiversity in the planet, and in these times of climate change and mega-extinctions, the need for efficient, good quality research is more pressing than in the past. However, the statistical component in research published by tropical authors sometimes suffers from poor quality in data collection; mediocre or bad experimental design and a rigid and outdated view of data analysis. To suggest improvements in their statistical education, we listed all the statistical tests and other quantitative analyses used in two leading tropical journals, the Revista de Biología Tropical and Biotropica, during a year. The 12 most frequent tests in the articles were: Analysis of Variance (ANOVA, Chi-Square Test, Student’s T Test, Linear Regression, Pearson’s Correlation Coefficient, Mann-Whitney U Test, Kruskal-Wallis Test, Shannon’s Diversity Index, Tukey’s Test, Cluster Analysis, Spearman’s Rank Correlation Test and Principal Component Analysis. We conclude that statistical education for tropical biologists must abandon the old syllabus based on the mathematical side of statistics and concentrate on the correct selection of these and other procedures and tests, on their biological interpretation and on the use of reliable and friendly freeware. We think that their time will be better spent understanding and protecting tropical ecosystems than trying to learn the mathematical foundations of statistics: in most cases, a well designed one-semester course should be enough for their basic requirements. Rev. Biol. Trop. 59 (3: 983-992. Epub 2011 September 01.Los biólogos tropicales estudian la biodiversidad más rica y amenazada del planeta, y en estos tiempos de cambio climático y mega-extinción, la necesidad de investigación de buena calidad es más acuciante que en el pasado. Sin embargo, el componente estadístico en la investigación publicada por los autores tropicales adolece a veces

  19. Cavitation erosion prediction on Francis turbines

    Energy Technology Data Exchange (ETDEWEB)

    Bourdon, P.; Farhat, M.; Simoneau, R.; Lavigne, P. [Hydro-Quebec, Montreal, PQ (Canada); Pereira, F.; Dupont, P.; Avellan, F.; Caron, J.F. [IMHEF/EPFL, (France); Dorey, J.M.; Archer, A. [Electricite de France (EDF), 92 - Clamart (France). Dir. des Etudes et Recherches; and others

    1997-12-31

    On-board aggressiveness measurement methods were tested on a severely eroded prototype blade of a 266 MW Francis turbine: pressure, pit counting, DECER electrochemical and vibration measurements. The test program provided understanding of the heterogeneous erosion distribution of the prototype blades and quantitative data for comparison in subsequent tests on the model of the machine. Model tests and flow analysis were also performed, to detect cavitation on a Francis turbine model. The results are compared to those obtained on the prototype measurements. The model used for that study is built on the basis of a geometrical recovery of one of the most eroded blade of the prototype. Different methods were investigated to predict cavitation erosion on Francis turbines from model. They are based on measurement of pitting, pressure fluctuations and acceleration. The methods proposed are suitable to measure cavitation aggressiveness on model and on prototype, and that the level on the model is several orders of magnitude smaller than on the prototype. (author) 18 refs.

  20. Meet EPA Biologist Thomas Knudsen, Ph.D.

    Science.gov (United States)

    Dr. Tom Knudsen is a developmental systems biologist at EPA's Center for Computational Toxicology. His research focuses on the potential for chemicals to disrupt prenatal development—one of the most important life stages.

  1. From political economy to sociology: Francis Galton and the social-scientific origins of eugenics.

    Science.gov (United States)

    Renwick, Chris

    2011-09-01

    Having coined the word 'eugenics' and inspired leading biologists and statisticians of the early twentieth century, Francis Galton is often studied for his contributions to modern statistical biology. However, whilst documenting this part of his work, historians have frequently neglected crucial aspects of what motivated Galton to establish his eugenics research programme. Arguing that his work was shaped more by social than by biological science, this paper addresses these oversights by tracing the development of Galton's programme, from its roots in a debate about political economy to his appeals for it to be taken up by sociologists. In so doing, the paper not only returns Galton's ideas to their original context but also provides a reason to reflect on the place of the social sciences in history-of-science scholarship.

  2. Homage to Francis Perrin - 1901-1992

    International Nuclear Information System (INIS)

    1994-05-01

    Francis Perrin had a brilliant and rapid career. He was a strict and honest man. He had a fast intelligence, a huge knowledge, he was faithful. Finally his courtesy and his generosity had made of him an outstanding and model personality very little known because of his extreme discretion. He lived his professional career (1920-1970) with passion. He thought that science might be one mankind heritage. He worked in CEA and played a crucial role in the CERN creation. He was an accomplished scientist since he tackled the mathematics, physics, and even chemistry scope. 52 refs

  3. Failure analysis of a Francis turbine runner

    Energy Technology Data Exchange (ETDEWEB)

    Frunzaverde, D; Campian, V [Research Center in Hydraulics, Automation and Heat Transfer, ' Eftimie Murgu' University of Resita P-ta Traian Vuia 1-4, RO-320085, Resita (Romania); Muntean, S [Centre of Advanced Research in Engineering Sciences, Romanian Academy - Timisoara Branch Bv. Mihai Viteazu 24, RO-300223, Timisoara (Romania); Marginean, G [University of Applied Sciences Gelsenkirchen, Neidenburger Str. 10, 45877 Gelsenkirchen (Germany); Marsavina, L [Department of Strength, ' Politehnica' University of Timisoara, Bv. Mihai Viteazu 1, RO-300222, Timisoara (Romania); Terzi, R; Serban, V, E-mail: gabriela.marginean@fh-gelsenkirchen.d, E-mail: d.frunzaverde@uem.r [Ramnicu Valcea Subsidiary, S.C. Hidroelectrica S.A., Str. Decebal 11, RO-240255, Ramnicu Valcea (Romania)

    2010-08-15

    The variable demand on the energy market requires great flexibility in operating hydraulic turbines. Therefore, turbines are frequently operated over an extended range of regimes. Francis turbines operating at partial load present pressure fluctuations due to the vortex rope in the draft tube cone. This phenomenon generates strong vibrations and noise that may produce failures on the mechanical elements of the machine. This paper presents the failure analysis of a broken Francis turbine runner blade. The failure appeared some months after the welding repair work realized in situ on fatigue cracks initiated near to the trailing edge at the junction with the crown, where stress concentration occurs. In order to determine the causes that led to the fracture of the runner blade, the metallographic investigations on a sample obtained from the blade is carried out. The metallographic investigations included macroscopic and microscopic examinations, both performed with light and scanning electron microscopy, as well as EDX - analyses. These investigations led to the conclusion, that the cracking of the blade was caused by fatigue, initiated by the surface unevenness of the welding seam. The failure was accelerated by the hydrogen embrittlement of the filling material, which appeared as a consequence of improper welding conditions. In addition to the metallographic investigations, numerical computations with finite element analysis are performed in order to evaluate the deformation and stress distribution on blade.

  4. Failure analysis of a Francis turbine runner

    International Nuclear Information System (INIS)

    Frunzaverde, D; Campian, V; Muntean, S; Marginean, G; Marsavina, L; Terzi, R; Serban, V

    2010-01-01

    The variable demand on the energy market requires great flexibility in operating hydraulic turbines. Therefore, turbines are frequently operated over an extended range of regimes. Francis turbines operating at partial load present pressure fluctuations due to the vortex rope in the draft tube cone. This phenomenon generates strong vibrations and noise that may produce failures on the mechanical elements of the machine. This paper presents the failure analysis of a broken Francis turbine runner blade. The failure appeared some months after the welding repair work realized in situ on fatigue cracks initiated near to the trailing edge at the junction with the crown, where stress concentration occurs. In order to determine the causes that led to the fracture of the runner blade, the metallographic investigations on a sample obtained from the blade is carried out. The metallographic investigations included macroscopic and microscopic examinations, both performed with light and scanning electron microscopy, as well as EDX - analyses. These investigations led to the conclusion, that the cracking of the blade was caused by fatigue, initiated by the surface unevenness of the welding seam. The failure was accelerated by the hydrogen embrittlement of the filling material, which appeared as a consequence of improper welding conditions. In addition to the metallographic investigations, numerical computations with finite element analysis are performed in order to evaluate the deformation and stress distribution on blade.

  5. Francis Crick: A Singular Approach to Scientific Discovery.

    Science.gov (United States)

    Lawrence, Peter A

    2016-12-01

    Francis' office window (at the Salk) commanded a panorama of the Pacific. "This grand natural scene was a physical correlate of Francis's intellectual world: wide-ranging, brilliantly lit, a little overawing, but also immensely inviting and above all an exciting place to be." (Mitchison, 2004). Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Development of a 5kw Francis Turbine Runner Using Computation ...

    African Journals Online (AJOL)

    A small scale Francis turbine runner for a turbine located at Awba dam in the University of Ibadan with designed head and flow rate of 6m and 0.244m3/s is designed. The basic design of the Francis turbine runner is completed based on basic fluid dynamics turbo machinery principles. A 2-D and 3-D steady state, ...

  7. [Sir Francis Galton: the father of eugenics].

    Science.gov (United States)

    Aubert-Marson, Dominique

    2009-01-01

    Not only was Sir Francis Galton a famous geographer and statistician, he also invented "eugenics" in 1883. Eugenics, defined as the science of improving racial stock, was developed from a new heredity theory, conceived by Galton himself, and from the evolution theory of Charles Darwin, transposed to human society by Herbert Spencer. Galton's eugenics was a program to artificially produce a better human race through regulating marriage and thus procreation. Galton put particular emphasis on "positive eugenics", aimed at encouraging the physically and mentally superior members of the population to choose partners with similar traits. In 1904, he presented his ideas in front of a vast audience of physicians and scientists in London. His widely-publicized lecture served as the starting point for the development of eugenics groups in Europe and the United States during the first half of the 20th century.

  8. O duplo legado de Francis Poulenc

    Directory of Open Access Journals (Sweden)

    Joana Resende

    2009-12-01

    Full Text Available Déjàvu,or better,déjà écouté is an appropriate expression to describe an audition of certain works by Francis Poulenc (1899-1963. A sui-generis character in 20th century music, Poulenc has questioned the whole heritage that came before him, French or not, according to the premises of the group he belonged to, Les Six, although not always reaching similar results. His main concern was to make good music, an ideal not far from that of Debussy, “music should humbly seek to please” (Harry Halbreich. This article approaches the use of quotation and other processes of allusion in the works by Poulenc, as seen in his voice and piano mélodies cycle La fraîcheur et le feu, identifying thematic, melodic, and harmonic, origins used coherently in several pieces. and helping to solidly build his musical language.

  9. the contrasting attitudes of plant breeders and molecular biologists ...

    Indian Academy of Sciences (India)

    Socialization into disciplinary cultures, organizational factors and individual anxieties seem to inhibit inter-disciplinary collaboration. The majority of rice breeders and a small group of molecular biologists emphasize the relative merits of marker-assisted selection (MAS) in the near term vis-à-vis the currently controversial ...

  10. Dr Jacob van der Land, marine biologist extraordinary

    NARCIS (Netherlands)

    Bruggen, van A.C.

    2001-01-01

    This contribution is an attempt to sketch the life and works of Dr Jacob van der Land, curator of worms and chief marine biologist of the National Museum of Natural History, on the occasion of his official retirement. Born in 1935, Jacob van der Land read biology at Leiden University (1958-1964),

  11. Assessing Attitude towards Religion: The Astley-Francis Scale of Attitude towards Theistic Faith

    Science.gov (United States)

    Astley, Jeff; Francis, Leslie J.; Robbins, Mandy

    2012-01-01

    This study builds on the research tradition modelled by the Francis Scale of Attitude towards Christianity, the Katz-Francis Scale of Attitude towards Judaism, the Sahin-Francis Scale of Attitude towards Islam and the Santosh-Francis Scale of Attitude towards Hinduism to propose a generic instrument concerned with attitudes towards theistic faith.…

  12. Francis Goyat kuuleb pühapäeval

    Index Scriptorium Estoniae

    2003-01-01

    Belgia kitarristist Francis Goyast, kontsertidest Pärnu kontserdimajas 19. nov., Tartus Vanemuise kontserdimajas 21.nov ja Tallinnas Estonia kontserdisaalis 23. nov., heliplaadist "Pleased to meet You, Mr. Valgre"

  13. Francis Bacon: “pintar sensações” (Francis Bacon: “to paint sensations”)

    OpenAIRE

    Borges, Sonia; UVA

    2013-01-01

    RESUMO O texto aborda, pela via da psicanálise, o que consideramos como o “método” de Francis Bacon: “pintar sensações”. Para isto, tomo, como referências principais, a Carta 52 (1896), da correspondência de Freud com Fliess, e Em busca do tempo perdido, romance de Marcel Proust ([1922] 1995), observando a possibilidade de considerar o que Proust nomeia como “memória involuntária” e o seu papel no processo criativo como uma ilustração esclarecedora do que Freud nos traz na Carta sobre a estr...

  14. A POÉTICA DE FRANCIS BACON

    Directory of Open Access Journals (Sweden)

    Sonia Borges

    2013-02-01

    Full Text Available A partir da perspectiva psicanalítica, a autora aborda a obra de Francis Bacon se utilizando de uma concepção estética que a reconhece como uma realidade ontológica. Dessa forma, considera que como obra de arte, são seus próprios elementos constitutivos, numa tensão interna, que são capazes de provocar efeitos ou as sensações que são o seu objetivo último conforme defendia Bacon. Em sua análise a autora examina e discute a dialética “tempo - espaço”, revelada pelo poeta pintor, como sendo de especial interesse para a clínica psicanalítica na medida em que esclarece importantes questões relativas ao Real como impossível, tal como o compreendeu Lacan. A pintura de Bacon examinada como referência à “sublimação criacionista da pulsão de morte” permite, segundo a autora, vislumbrarmos o para além da cadeia significante. Conclui que a arte, assim como a clínica psicanalítica, supõe deslocamentos subjetivos que implicam corte - rompimento com a tendência unificadora e pacificadora de Eros.

  15. THE DESCENT OF LANGUAGE. A CONVERSATION BETWEEN TWO JOBLESS BIOLOGISTS

    Directory of Open Access Journals (Sweden)

    D'Angelo Giovanni

    2013-12-01

    Full Text Available Seen from the perspective of a biologist, the issue of the origin of language contains an inherent ambiguity. On the one hand, one might think to explore the cognitive features or even the anatomical structures related to communication through the peculiar medium called verbal language, a characteristic property emergent among the Homo sapiens. On the other hand, if one decides to restrict oneself to the formal definition of language as a system of signs for encoding information, then, the human-specific nature of language becomes less convincing and the temptation to look into non-human languages allows a provocative question. Was human verbal language an invention or a discovery? In the following two biologists informally discuss about the concept of non-verbal biological languages.

  16. HydroHillChart – Francis module. Software used to Calculate the Hill Chart of the Francis Hydraulic Turbines

    Directory of Open Access Journals (Sweden)

    Dorian Nedelcu

    2015-07-01

    Full Text Available The paper presents the Hydro Hill Chart - Francis module application, used to calculate the hill chart of the Pelton, Francis and Kaplan hydraulic turbine models, by processing the data measured on the stand. After describing the interface and menu, the input data is graphically presented and the universal characteristic for measuring scenarios ao=const. and n11=const is calculated. Finally, the two calculated hill charts are compared through a graphical superimposition of the isolines.

  17. Measurement of pressure pulsations in Francis turbines

    Energy Technology Data Exchange (ETDEWEB)

    Kobro, Einar

    2010-11-15

    The work presented in this thesis involves preparation and execution of measurements on Francis runners. The measurements were performed by means of onboard measuring equipment both in model runners and full-scale prototype runners. Also, analysis of the measured data, and the discussion of the results, is presented. The measurements resulted in large data sets. These data sets were used by the author to investigate the dynamic pressure and strain in the runners. The results of the analysis can be used as input in future turbine design. Andritz Hydro AG has used the data for verification of their numerical simulation tools. In connection with the refurbishment of Tokke power plant, two model runners were made available for onboard pressure measurements. To investigate the dynamic pressure in these runners, methods for integration of pressure transducers in the runner blades needed to be developed. After initial difficulties during the preparation, successful measurements were obtained from both model runners. At Tokke power plant, both the original and replacement runners were made accessible for onboard pressure and strain gauge measurements. On the original Kvaerner Brug AS runner, the test was prepared and performed by the author. This test failed, due to water intrusion in the logging chain. The second test was performed on the Andritz Hydro AG replacement runner. This test was prepared and performed by the author in close cooperation with Andritz Hydro AG, and the results were successful. The analysis results from both model and prototype runners show that the wake leaving the guide vanes is the most severe source of dynamic pressure in the runner. The draft tube vortex rope pulsation propagates upstream the runner, but does not appear as a significant frequency in the runner strain measurements. (Author)

  18. Dr Jacob van der Land, marine biologist extraordinary

    OpenAIRE

    Bruggen, van, A.C.

    2001-01-01

    This contribution is an attempt to sketch the life and works of Dr Jacob van der Land, curator of worms and chief marine biologist of the National Museum of Natural History, on the occasion of his official retirement. Born in 1935, Jacob van der Land read biology at Leiden University (1958-1964), where he obtained his Ph.D. in 1970 on a treatise on the Priapulida under the supervision of Prof. Dr L.D. Brongersma. In 1964 he was appointed curator of worms in the museum. Later on he took over l...

  19. Numerical Study of a High Head Francis Turbine with Measurements from the Francis-99 Project

    International Nuclear Information System (INIS)

    Wallimann, H; Neubauer, R

    2015-01-01

    For the Francis-99 project initiated by the Norwegian University of Science and Technology (NTNU, Norway) and the Luleå University of Technology (LTU, Sweden) numerical flow simulation has been performed and the results compared to experimentally obtained data. The full machine including spiral casing, stay vanes, guide vanes, runner and draft tube was simulated transient for three operating points defined by the Francis-99 organisers. Two sets of results were created with differing time steps. Additionally, a reduced domain was simulated in a stationary manner to create a complete cut along constant prototype head and constant prototype discharge. The efficiency values and shape of the curves have been investigated and compared to the experimental data. Special attention has been given to rotor stator interaction (RSI). Signals from several probes and their counterpart in the simulation have been processed to evaluate the pressure fluctuations occurring due to the RSI. The direct comparison of the hydraulic efficiency obtained by the full machine simulation compared to the experimental data showed no improvement when using a 1° time step compared to a coarser 2° time step. At the BEP the 2° time step even showed a slightly better result with an absolute deviation 1.08% compared with 1.24% for the 1° time step. At the other two operating points the simulation results were practically identical but fell short of predicting the measured values. The RSI evaluation was done using the results of the 2° time step simulation, which proved to be an adequate setting to reproduce pressure signals with peaks at the correct frequencies. The simulation results showed the highest amplitudes in the vaneless space at the BEP operating point at a location different from the probe measurements available. This implies that not only the radial distance, but the shape of the vaneless space influences the RSI

  20. On Francis Crick, the genetic code, and a clever kid.

    Science.gov (United States)

    Goldstein, Bob

    2018-04-02

    A few years ago, Francis Crick's son told me a story that I can't get out of my mind. I had contacted Michael Crick by email while digging through the background of the researchers who had cracked the genetic code in the 1960s. Francis had died in 2004, and I was contacting some of the people who knew him when he was struggling to decipher the code. Francis didn't appear to struggle often - he is known mostly for his successes - and, as it turns out, this one well-known struggle may have had a clue sitting just barely out of sight. Copyright © 2018 Elsevier Ltd. All rights reserved.

  1. Don Quijote y Hamlet

    Directory of Open Access Journals (Sweden)

    Lúdovik B. Osterc

    2002-12-01

    Hamlet está loco, es un alucinado que duda de sus propios sentidos. Para él existe sólo un lado negro de la existencia, su único objeto es llegar más pronto al descubrimiento del crimen. Es egocentrico, ne cree en nada, eternamente mira en su interior, se alimenta en su desprecio de sí mismo y su sufrimiento es mucho más doloroso.que aquel de Don Quijote. Don Quijote, al contrario, cree en el hombre y su futuro. Su ideal es implantar por la fuerza, la verdad, el bien y la justicia en la tierra. Para servir a su ideal, está dispuesto a sufrir todas las posibles privaciones. Representa la fe en la verdad. Es ridículo y quizás el más cómico tipo disenado jamás por un literato. Hamlet es el hijo del rey muerte, mientras que Don Quijote está pobre. Se hace los enemigos imaginarios y lucha contra ellos, mientras que Hamlet no cree en las ilusiones (siempre duda, y tampoco no combatiría si supiera que son sinónimos de opresores. Continua con la examinación de la actitud del pueblo o sus representantes hacia Don Quijote y Hamlet y viceversa. Polonia es el representante de las multitudes populares ante Hamlet, Sancho lo es ante su senor. El primero es de sano pensamiento y al mismo tiempo un viejo charalatán. Para él Hamlet no es tanto un loco como un nino y le parece inútil para la sociedad. Sancho Pansa está persuadido de que su senor está loco, pero le está leal hasta la muerte. Don Quijote simpatiza profundamente con el pueblo, pero la única persona con la que se entiende verdaderamente es Sancho Pansa (uno no puede vivir sin otro. La actitud de Hamlet es completamente diferente, él desprecia las multitudes populares, porque también desprecia a sí mismo. social: el tedio, el hastío, el descontento de la vida, desorientación espiritual y la eclipse de la fe, miéntras que Don Quijote encarna el mundo libre, bien estar y la felicidad de los seres humanos. Por eso y porque es un ideal el más humano, generoso, noble y elevado, el autor del

  2. Improving interactions between animal rights groups and conservation biologists.

    Science.gov (United States)

    Perry, Dan; Perry, Gad

    2008-02-01

    Invasive species are often considered to be a major threat to biodiversity, leading conservation biologists to often recommend their complete eradication. Animal rights groups typically categorically oppose killing animals, and their opposition has brought eradication attempts of gray squirrels in northern Italy (Europe) and mute swans in Vermont to a halt. As a result native red squirrels may disappear from Europe and ecosystem-wide impacts are expected to be caused by the swan. In contrast, cooperation between managers and animal rights groups has resulted in a successful control program for feral pigs in Fort Worth, Texas (U.S.A.). The philosophical differences between animal rights and conservation biologists' views make cooperation seem unlikely, yet documented cases of cooperation have been beneficial for both groups. We recommend that managers dealing with invasive species should consult with social scientists and ethicists to gain a better understanding of the implications of some of their policy decisions. In addition, we recommend that animal rights groups do more to support alternatives to lethal control, which are often excluded by economic limitations. Prevention of arrival of invasive species via application of the precautionary principle may be an especially productive avenue for such collaboration because it fits the goals and values of both groups.

  3. Verdade e método em Francis Bacon

    OpenAIRE

    Secco, Márcio

    2004-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas. Programa de Pós-Graduação em Filosofia. Estudo sobre o método e o conceito de verdade defendido por Francis Bacon, sendo nossos principais objetivos nesse trabalho: a) esclarecer algumas questões relativas ao método baconiano, principalmente no que se refere ao uso de hipóteses; b) apresentar uma interpretação falibilista da teoria de Francis Bacon, mostrando que a verdade e a utilidade...

  4. Biological and communication skills needed for introduced fish biologists

    Science.gov (United States)

    Bonar, Scott A.

    2016-01-01

    What skills and knowledge will a new graduate seeking employment need to work with introduced fishes? Clearly, success in introduced species management—similar to other disciplines in fisheries—requires a mixture of scientific and communication skills. However, specific abilities especially important to a biologist who manages introduced fishes should be highlighted. Unlike most other management strategies, stocking an introduced species can result in unintended and irreversible impacts, so particular care must be employed when stocking is considered. Furthermore, fish populations in areas outside of the introduced species management area might also be affected, usually negatively, if the introduced fish escapes. Therefore, rock-solid knowledge of basic aquatic ecology, including risk management; fish taxonomy (so the wrong fish species is not mistakenly stocked!); familiarity with human values of both the time and the place (which requires communication skills); and a strong understanding of human history are all important.

  5. Engineers are from PDMS-land, Biologists are from Polystyrenia.

    Science.gov (United States)

    Berthier, Erwin; Young, Edmond W K; Beebe, David

    2012-04-07

    As the integration of microfluidics into cell biology research proceeds at an ever-increasing pace, a critical question for those working at the interface of both disciplines is which device material to use for a given application. While PDMS and soft lithography methods offer the engineer rapid prototyping capabilities, PDMS as a material has characteristics that have known adverse effects on cell-based experiments. In contrast, while polystyrene (PS), the most commonly used thermoplastic for laboratory cultureware, has provided decades of grounded and validated research conclusions in cell behavior and function, PS as a material has posed significant challenges in microfabrication. These competing issues have forced microfluidics engineers and biologists to make compromises in how they approach specific research questions, and furthermore, have attenuated the impact of microfluidics on biological research. In this review, we provide a comparison of the attributes of PDMS and PS, and discuss reasons for their popularity in their respective fields. We provide a critical evaluation of the strengths and limitations of PDMS and PS in relation to the advancement and future impact on microfluidic cell-based studies and applications. We believe that engineers have a responsibility to overcome any challenges associated with microfabrication, whether with PS or other materials, and that engineers should provide options and solutions that assist biologists in their experimental design. Our goal is not to advocate for any specific material, but provide guidelines for researchers who desire to choose the most suitable material for their application, and suggest important research directions for engineers working at the interface between microfabrication technology and biological application. This journal is © The Royal Society of Chemistry 2012

  6. Francis Bacon and the Historiography of Scientific Rhetoric.

    Science.gov (United States)

    Zappen, James P.

    1989-01-01

    Reviews three twentieth-century interpretations of Francis Bacon's science and rhetoric: positivistic science and the plain style; institutionalized science and its more highly figured style; and democratic science. Presents the author's own interpretation, and concludes that each interpretation reflects different perceptions of the good of the…

  7. 60 years ago, Francis Crick changed the logic of biology.

    Directory of Open Access Journals (Sweden)

    Matthew Cobb

    2017-09-01

    Full Text Available In September 1957, Francis Crick gave a lecture in which he outlined key ideas about gene function, in particular what he called the central dogma. These ideas still frame how we understand life. This essay explores the concepts he developed in this influential lecture, including his prediction that we would study evolution by comparing sequences.

  8. 60 years ago, Francis Crick changed the logic of biology

    Science.gov (United States)

    2017-01-01

    In September 1957, Francis Crick gave a lecture in which he outlined key ideas about gene function, in particular what he called the central dogma. These ideas still frame how we understand life. This essay explores the concepts he developed in this influential lecture, including his prediction that we would study evolution by comparing sequences. PMID:28922352

  9. Scientific Cousins: The Relationship between Charles Darwin and Francis Galton

    Science.gov (United States)

    Fancher, Raymond E.

    2009-01-01

    This article traces the personal as well as the intellectual and scientific relationship between Charles Darwin and his younger half-cousin Francis Galton. Although they had been on friendly terms as young men, and Darwin had in some ways been a role model for Galton, the two did not share major scientific interests until after the publication of…

  10. Master equation and runaway speed of the Francis turbine

    Science.gov (United States)

    Zhang, Zh.

    2018-04-01

    The master equation of the Francis turbine is derived based on the combination of the angular momentum (Euler) and the energy laws. It relates the geometrical design of the impeller and the regulation settings (guide vane angle and rotational speed) to the discharge and the power output. The master equation, thus, enables the complete characteristics of a given Francis turbine to be easily computed. While applying the energy law, both the shock loss at the impeller inlet and the swirling loss at the impeller exit are taken into account. These are main losses which occur at both the partial load and the overloads and, thus, dominantly influence the characteristics of the Francis turbine. They also totally govern the discharge of the water through the impeller when the impeller is found in the standstill. The computations have been performed for the discharge, the hydraulic torque and the hydraulic efficiency. They were also compared with the available measurements on a model turbine. Excellent agreement has been achieved. The computations also enable the runaway speed of the Francis turbine and the related discharge to be determined as a function of the setting angle of the guide vanes.

  11. Sunrayce 97 Continues Day 7 - Smith Center to St. Francis

    Science.gov (United States)

    Manager (202) 586-0713 St. Francis, Kan. -- It was a close race for the top three places on the 7th day of running great. It's a solid car. We may not have the fastest or most efficient vehicle in the race, but we withdraw from the race yesterday due to suspension problems. The team was presented an "Inspector's

  12. 60 years ago, Francis Crick changed the logic of biology.

    Science.gov (United States)

    Cobb, Matthew

    2017-09-01

    In September 1957, Francis Crick gave a lecture in which he outlined key ideas about gene function, in particular what he called the central dogma. These ideas still frame how we understand life. This essay explores the concepts he developed in this influential lecture, including his prediction that we would study evolution by comparing sequences.

  13. Major historical developments in the design of water wheels and Francis hydroturbines

    International Nuclear Information System (INIS)

    Lewis, B J; Cimbala, J M; Wouden, A M

    2014-01-01

    The first record of water wheels dates back to ancient Greece. Over the next several centuries the technology spread all over the world. The process of arriving at the design of the modern Francis runner lasted from 1848 to approximately 1920. Though the modern Francis runner has little resemblance to the original turbines designed by James B. Francis in 1848, it became know as the Francis turbine around 1920, in honor of his many contributions to hydraulic engineering analysis and design. The modern Francis turbine is the most widely used turbine design today, particularly for medium head and large flow rate situations, and can achieve over 95% efficiency

  14. Charles William Lacaillade. Biologist, Parasitologist, Educator, and Mentor.

    Science.gov (United States)

    Imperato, Pascal James

    2017-02-01

    Charles William Lacaillade (1904-1978) was an eminent biologist in the middle decades of the twentieth century. He was born in Lawrence, Massachusetts of parents whose ancestors were French Canadians. His father, also named Charles William Lacaillade, was a dentist who graduated from Tufts University School of Dentistry in 1898. His mother, Elodia Eno, came from a family of very successful businessmen. Lacaillade was the third of six children. His two older brothers, Harold Carleton and Hector Eno, both graduated from the University of Louisville, School of Dentistry, while his younger brother, Lawrence, became a businessman. His sister, Luemma, married Dr. Henry Steadman, a veterinarian, while his youngest sister, Gloria, married a U.S. Army officer, Lieutenant Colonel Victor Anido. Lacaillade received his MS and PhD degrees in biology and zoology from Harvard University. He then became a fellow at The Rockefeller Institute for Medical Research. At both institutions, he studied under some of the most eminent biological scientists of the time. These included Rudolf W. Glaser, George Howard Parker, Theobald Smith, Carl TenBroeck, and William Morton Wheeler. At the Rockefeller Institute, he co-discovered the vector and mode of transmission of Eastern Equine Encephalomyelitis. This discovery, and the research he conducted with Rudolf W. Glaser, quickly established him as an outstanding biological researcher. However, a change in leadership at the Rockefeller Institute resulted in research priorities being given to the disciplines of general physiology, physical chemistry, and nutrition. This shift in the research agenda away from the biological sciences precluded career advancement at the Rockefeller Institute for post-doctoral fellows like Lacaillade. It was the height of the Great Depression, and even biologists with terminal doctoral degrees found it difficult to find positions. In 1935, Lacaillade accepted a position as an assistant in biology at St. John

  15. Eukaryotic systematics: a user's guide for cell biologists and parasitologists.

    Science.gov (United States)

    Walker, Giselle; Dorrell, Richard G; Schlacht, Alexander; Dacks, Joel B

    2011-11-01

    Single-celled parasites like Entamoeba, Trypanosoma, Phytophthora and Plasmodium wreak untold havoc on human habitat and health. Understanding the position of the various protistan pathogens in the larger context of eukaryotic diversity informs our study of how these parasites operate on a cellular level, as well as how they have evolved. Here, we review the literature that has brought our understanding of eukaryotic relationships from an idea of parasites as primitive cells to a crystallized view of diversity that encompasses 6 major divisions, or supergroups, of eukaryotes. We provide an updated taxonomic scheme (for 2011), based on extensive genomic, ultrastructural and phylogenetic evidence, with three differing levels of taxonomic detail for ease of referencing and accessibility (see supplementary material at Cambridge Journals On-line). Two of the most pressing issues in cellular evolution, the root of the eukaryotic tree and the evolution of photosynthesis in complex algae, are also discussed along with ideas about what the new generation of genome sequencing technologies may contribute to the field of eukaryotic systematics. We hope that, armed with this user's guide, cell biologists and parasitologists will be encouraged about taking an increasingly evolutionary point of view in the battle against parasites representing real dangers to our livelihoods and lives.

  16. Mimesis in Don Quixote

    Directory of Open Access Journals (Sweden)

    Giselle von der Walde

    2006-04-01

    Full Text Available Resumen:Frente a argumentos tomados de las poéticas neoaristotélicas que esgrime el canónigo para condenar los libros de caballerías, don Quijote pretende mostrar con su propio ejemplo, que ese tipo de lecturas no llevan a la locura ni al abandono de sí mismo, sino que, por el contrario, sacan lo mejor de la naturaleza de un individuo y lo hacen mejor persona. Este es el único tipo de imitación que Platón acepta en la República, pues más que un remedo o una suplantación, implica emulación. Este escrito se propone mirar, a partir del diálogo con el canónigo de Toledo (I, 49-50, cómo en sus conductas miméticas desde el comienzo de la obra, don Quijote entiende la imitación como emulación; en consecuencia se intenta demostrar que el efecto de la literatura en el caballero manchego parece ser el tipo de mimesis que Platón acepta en el libro III de la República.Abstract:Don Quijote demonstrates with the example of his own life the error made by the Canon of Toledo when the latter uses the arguments of the neo-Aristotelian poets to condemn the novels of chivalric romance. Quijote tries to show that reading the chivalric romances leads to neither madness nor the abandonment of the self, but, on the contrary, brings out the best in a person’s nature, and makes one a better person. This is the only type of imitation that Plato accepts in the Republic, because, unlike the mere copying of a person, or the substitution of one person for another, it implies a type of emulation. Starting with the dialogue of the Canon of Toledo (I, 49-50, this paper shows how, in his mimetic behavior, Don Quijote understands imitation as emulation. As a result, the paper shows that the effect of literature on the gentleman from La Mancha is the type of mimesis of which Plato approves in book III of the Republic.

  17. Don Isidoro Laverde Amaya

    Directory of Open Access Journals (Sweden)

    Carlos López Narváez

    1961-03-01

    Full Text Available A la calidad sustantiva de los polígrafos, -estirpe de los Vergara, Eduardo Posada, Gustavo Arboleda, Otero Muñoz, Samper Ortega, Gómez Restrepo para nombrar solo algunos de los que "nos han precedido con la señal de la fe", como dice el sacro ritual, y en el servicio de las Letras patrias- pertenece con mérito eximio el prócer de la bibliografía colombiana, don Isidoro Laverde Amaya.

  18. Francis Bacon: The Real's Brutality. The Figure and the Other

    Directory of Open Access Journals (Sweden)

    Guido Mannucci

    2014-03-01

    Full Text Available Getting in front of painting by Francis Bacon touches you deeply. I’m talking about aesthetics, sensations: resounding flow that strikes abruptly, making futile any search for meaning. Francis Bacon circumvents the figurative, the meaning, he aims to the figural: to feelings, not words. Beauty, in his paintings, shows itself in the peaceful union of the positive and of its contrary; if the negative wasn’t there, though, his paintings wouldn’t exude such a brutal sense of reality. This essay investigates the figure of Francis Bacon and the spectator – the Other – as he tries to confront the painting. Bacon will be analysed using a purely phenomenological approach, with references that range from Merleau-Ponty to Martin Heidegger; the meeting-collision between the spectator and the painting, instead, will be examined taking inspiration from the Winnicott’s thesis on the relationship between Bacon and mirrors in the painter’s childhood. In order to take distance from Winnicott’s psychoanalytical approach, this essay will focus on the relationship between spectator and painting from a more anthropological point of view. 

  19. Using clinical supervision to improve the quality and safety of patient care: a response to Berwick and Francis.

    Science.gov (United States)

    Tomlinson, Jonathon

    2015-06-11

    After widely publicised investigations into excess patient deaths at Mid Staffordshire hospital the UK government commissioned reports from Robert Francis QC and Professor Don Berwick. Among their recommendations to improve the quality and safety of patient care were lifelong learning, professional support and 'just culture'. Clinical supervision is in an excellent position to support these activities but opportunities are in danger of being squeezed out by regulatory and managerial demands. Doctors who have completed their training are responsible for complex professional judgements for which narrative supervision is particularly helpful. With reference to the literature and my own practice I propose that all practicing clinicians should have regular clinical supervision. Clinical supervision has patient-safety and the quality of patient care as its primary purposes. After training is completed, doctors may practice for the rest of their career without any clinical supervision, the implication being that the difficulties dealt with in clinical supervision are no longer difficulties, or are better dealt with some other way. Clinical supervision is sufficiently flexible to be adapted to the needs of experienced clinicians as its forms can be varied, though its functions remain focused on patient safety, good quality clinical care and professional wellbeing. The evidence linking clinical supervision to the quality and safety of patient care reveals that supervision is most effective when its educational and supportive functions are separated from its managerial and evaluative functions. Among supervision's different forms, narrative-based-supervision is particularly useful as it has been developed for clinicians who have completed their training. It provides ways to explore the complexity of clinical judgements and encourages doctors to question one another's authority in a supportive culture. To be successful, supervision should also be professionally led and

  20. Cost of enlarged operating zone for an existing Francis runner

    Science.gov (United States)

    Monette, Christine; Marmont, Hugues; Chamberland-Lauzon, Joël; Skagerstrand, Anders; Coutu, André; Carlevi, Jens

    2016-11-01

    Traditionally, hydro power plants have been operated close to best efficiency point, the more stable operating condition for which they have been designed. However, because of changes in the electricity market, many hydro power plants operators wish to operate their machines differently to fulfil those new market needs. New operating conditions can include whole range operation, many start/stops, extensive low load operation, synchronous condenser mode and power/frequency regulation. Many of these new operating conditions may impose more severe fatigue damage than the traditional base load operation close to best efficiency point. Under these conditions, the fatigue life of the runner may be significantly reduced and reparation or replacement cost might occur sooner than expected. In order to design reliable Francis runners for those new challenging operating scenarios, Andritz Hydro has developed various proprietary tools and design rules. These are used within Andritz Hydro to design mechanically robust Francis runners for the operating scenarios fulfilling customer's specifications. To estimate residual life under different operating scenarios of an existing runner designed years ago for best efficiency base load operation, Andritz Hydro's design rules and tools would necessarily lead to conservative results. While the geometry of a new runner can be modified to fulfil all conservative mechanical design rules, the predicted fatigue life of an existing runner under off-design operating conditions may appear rather short because of the conservative safety factor included in the calculations. The most precise and reliable way to calculate residual life of an existing runner under different operating scenarios is to perform a strain gauge measurement campaign on the runner. This paper presents the runner strain gage measurement campaign of a mid-head Francis turbine over all the operating conditions available during the test, the analysis of the measurement signals

  1. Design of large Francis turbine using optimal methods

    Science.gov (United States)

    Flores, E.; Bornard, L.; Tomas, L.; Liu, J.; Couston, M.

    2012-11-01

    Among a high number of Francis turbine references all over the world, covering the whole market range of heads, Alstom has especially been involved in the development and equipment of the largest power plants in the world : Three Gorges (China -32×767 MW - 61 to 113 m), Itaipu (Brazil- 20x750 MW - 98.7m to 127m) and Xiangjiaba (China - 8x812 MW - 82.5m to 113.6m - in erection). Many new projects are under study to equip new power plants with Francis turbines in order to answer an increasing demand of renewable energy. In this context, Alstom Hydro is carrying out many developments to answer those needs, especially for jumbo units such the planned 1GW type units in China. The turbine design for such units requires specific care by using the state of the art in computation methods and the latest technologies in model testing as well as the maximum feedback from operation of Jumbo plants already in operation. We present in this paper how a large Francis turbine can be designed using specific design methods, including the global and local optimization methods. The design of the spiral case, the tandem cascade profiles, the runner and the draft tube are designed with optimization loops involving a blade design tool, an automatic meshing software and a Navier-Stokes solver, piloted by a genetic algorithm. These automated optimization methods, presented in different papers over the last decade, are nowadays widely used, thanks to the growing computation capacity of the HPC clusters: the intensive use of such optimization methods at the turbine design stage allows to reach very high level of performances, while the hydraulic flow characteristics are carefully studied over the whole water passage to avoid any unexpected hydraulic phenomena.

  2. Design of large Francis turbine using optimal methods

    International Nuclear Information System (INIS)

    Flores, E; Bornard, L; Tomas, L; Couston, M; Liu, J

    2012-01-01

    Among a high number of Francis turbine references all over the world, covering the whole market range of heads, Alstom has especially been involved in the development and equipment of the largest power plants in the world : Three Gorges (China −32×767 MW - 61 to 113 m), Itaipu (Brazil- 20x750 MW - 98.7m to 127m) and Xiangjiaba (China - 8x812 MW - 82.5m to 113.6m - in erection). Many new projects are under study to equip new power plants with Francis turbines in order to answer an increasing demand of renewable energy. In this context, Alstom Hydro is carrying out many developments to answer those needs, especially for jumbo units such the planned 1GW type units in China. The turbine design for such units requires specific care by using the state of the art in computation methods and the latest technologies in model testing as well as the maximum feedback from operation of Jumbo plants already in operation. We present in this paper how a large Francis turbine can be designed using specific design methods, including the global and local optimization methods. The design of the spiral case, the tandem cascade profiles, the runner and the draft tube are designed with optimization loops involving a blade design tool, an automatic meshing software and a Navier-Stokes solver, piloted by a genetic algorithm. These automated optimization methods, presented in different papers over the last decade, are nowadays widely used, thanks to the growing computation capacity of the HPC clusters: the intensive use of such optimization methods at the turbine design stage allows to reach very high level of performances, while the hydraulic flow characteristics are carefully studied over the whole water passage to avoid any unexpected hydraulic phenomena.

  3. Transient CFD simulation of a Francis turbine startup

    International Nuclear Information System (INIS)

    Nicolle, J; Morissette, J F; Giroux, A M

    2012-01-01

    To assess the life expectancy of hydraulic turbines, it is essential to obtain the loading on the blades, especially during transient operations known to be the most damaging. This paper presents a simplified CFD setup to model the startup phase of a Francis turbine while it goes from rest to speed no-load condition. The fluid domain included one distributor sector coupled with one runner passage. The guide vane motion and change in the angular velocity were included in a commercial code with user functions. Comparisons between numerical results and measurements acquired on a full-size turbine showed that most of the flow physics occurring during startup were captured.

  4. Efficiency limit factor analysis for the Francis-99 hydraulic turbine

    Science.gov (United States)

    Zeng, Y.; Zhang, L. X.; Guo, J. P.; Guo, Y. K.; Pan, Q. L.; Qian, J.

    2017-01-01

    The energy loss in hydraulic turbine is the most direct factor that affects the efficiency of the hydraulic turbine. Based on the analysis theory of inner energy loss of hydraulic turbine, combining the measurement data of the Francis-99, this paper calculates characteristic parameters of inner energy loss of the hydraulic turbine, and establishes the calculation model of the hydraulic turbine power. Taken the start-up test conditions given by Francis-99 as case, characteristics of the inner energy of the hydraulic turbine in transient and transformation law are researched. Further, analyzing mechanical friction in hydraulic turbine, we think that main ingredients of mechanical friction loss is the rotation friction loss between rotating runner and water body, and defined as the inner mechanical friction loss. The calculation method of the inner mechanical friction loss is given roughly. Our purpose is that explore and research the method and way increasing transformation efficiency of water flow by means of analysis energy losses in hydraulic turbine.

  5. The green roof dilemma - discussion of Francis and Lorimer (2011).

    Science.gov (United States)

    Henry, Alexandre; Frascaria-Lacoste, Nathalie

    2012-08-15

    Urban ecosystems are the most complex mosaics of vegetative land cover that can be found. In a recent paper, Francis and Lorimer (2011) evaluated the reconciliation potential of living roofs and walls. For these authors, these two techniques for habitat improvement have strong potential for urban reconciliation ecology. However they have some ecological and societal limitations such as the physical extreme environmental characteristics, the monetary investment and the cultural perceptions of urban nature. We are interested in their results and support their conclusions. However, for a considerable time, green roofs have been designed to provide urban greenery for buildings and the green roof market has only focused on extensive roof at a restricted scale within cities. Thus, we have strong doubts about the relevance of their use as possible integrated elements of the network. Furthermore, without dynamic progress in research and the implementation of well-thought-out policies, what will be the real capital gain from green roofs with respect to land-use complementation in cities? If we agree with Francis and Lorimer (2011) considering that urban reconciliation ecology between nature and citizens is a current major challenge, then "adaptive collaborative management" is a fundamental requirement. Copyright © 2012 Elsevier Ltd. All rights reserved.

  6. LDA measurements in the Francis-99 draft tube cone

    International Nuclear Information System (INIS)

    Sundstrom, L R J; Amiri, K; Cervantes, M J; Bergan, C; Dahlhaug, O G

    2014-01-01

    Velocity measurements were performed in the draft tube cone of a 1:5.1 scaled model of the Tokke hydropower plant, Norway; also known as the Francis-99 model. Results from the laser Doppler anemometry measurements undertaken at three operating points will be used as validation data for an upcoming workshop on the state of the art of Francis turbine numerical simulation. With the turbine operating at the best efficiency point, a sensitivity analysis of the flow parameters head, flow rate and runner rotational speed shows that the effects on the dimensionless velocity profiles are small as long as n ED and Q ED are held constant. The results indicate a well-functioning turbine at the best efficiency point and high load. At the part load operating point, a vortex breakdown occurs which distorts the velocity profiles and significantly lowers the turbine's hydraulic efficiency. Frequency spectrums of each LDA signal at part load reveals a peak which is asynchronous to that of the runner angular speed. The peaks might be related to the precession of a rotating vortex rope but the characteristics of the LDA signals are different compared to previous studies involving rotating vortex ropes

  7. The Second Christ, Saint Francis of Assisi and ecological consciousness

    Directory of Open Access Journals (Sweden)

    Hendrik Viviers

    2014-01-01

    Full Text Available Even though the life stories of Jesus and the so-called second Christ, Francis of Assisi, incline to the fantastical, their value for a modern ecological consciousness is defendable. Behind Francis� personification of nature and his mystical experiences of nature lie an intuitive sense of interconnectedness and interdependence, of being fully part of the natural web of life (confirmed by empirical science. The same is true of the immanence of Jesus. Religious figures like Francis and Jesus can provide a sound moral attitude towards caring for the natural world, but attitudes need to be informed by scientific knowledge to act ecologically correct. A partnership between attitudes and knowledge hopefully contains good news for a sustainable �green� planet.Intradisciplinary and/or�interdisciplinary�implications: Ecological hermeneutics (part of liberation theology or hermeneutics challenges traditional theologies� often anthropocentric bias in the intra-disciplinary arena. It respects the interconnectedness or interdependence of human and non-human life, including the non-organic, empirically substantiated by natural science. This shared realisation allows for a fruitful inter-disciplinary discourse with science to address the global ecological crisis.

  8. Effect of Guide Vane Clearance Gap on Francis Turbine Performance

    Directory of Open Access Journals (Sweden)

    Ravi Koirala

    2016-04-01

    Full Text Available Francis turbine guide vanes have pivoted support with external control mechanism, for conversion of pressure to kinetic energy and to direct them to runner vanes. This movement along the support is dependent on variation of load and flow (operating conditions. Small clearance gaps between facing plates and the upper and lower guide vane tips are available to aid this movement, through which leakage flow occurs. This secondary flow disturbs the main flow stream, resulting performance loss. Additionally, these increased horseshoe vortex, in presence of sand, when crosses through the gaps, both the surfaces are eroded. This causes further serious effect on performance and structural property by increasing gaps. This paper discusses the observation of the severity in hydropower plants and effect of clearance gaps on general performance of the Francis turbine through computational methods. It also relates the primary result with the empirical relation for leakage flow prediction. Additionally, a possible method to computationally estimate thickness depletion has also been presented. With increasing clearance gap, leakage increases, which lowers energy conversion and turbine efficiency along with larger secondary vortex.

  9. Francis Bacon: constructing natural histories of the invisible.

    Science.gov (United States)

    Rusu, Doina-Cristina

    2012-01-01

    The natural histories contained in Francis Bacon's Historia naturalis et experimentalis seem to differ from the model presented in De augmentis scientiarum and the Descriptio globi intellectualis in that they are focused on the defining properties of matter, its primary schematisms and the spirits. In this respect, they are highly speculative. In this paper I aim to describe the Historia naturalis et experimentalis as a text about matter theory, the histories of which are ascending from what is most evident to the senses to what is least accessible to them. Moreover, the Latin natural histories are parts of a methodological procedure in which the provisional rules and axioms obtained in one history can be used as theoretical assumptions for another history, thereby permitting one to delve ever more profoundly into the structure of nature.

  10. The "Visual Shock" of Francis Bacon: an essay in neuroesthetics.

    Science.gov (United States)

    Zeki, Semir; Ishizu, Tomohiro

    2013-01-01

    In this paper we discuss the work of Francis Bacon in the context of his declared aim of giving a "visual shock."We explore what this means in terms of brain activity and what insights into the brain's visual perceptive system his work gives. We do so especially with reference to the representation of faces and bodies in the human visual brain. We discuss the evidence that shows that both these categories of stimuli have a very privileged status in visual perception, compared to the perception of other stimuli, including man-made artifacts such as houses, chairs, and cars. We show that viewing stimuli that depart significantly from a normal representation of faces and bodies entails a significant difference in the pattern of brain activation. We argue that Bacon succeeded in delivering his "visual shock" because he subverted the normal neural representation of faces and bodies, without at the same time subverting the representation of man-made artifacts.

  11. Francis Bacon: teory, method and contributions to the education

    Directory of Open Access Journals (Sweden)

    Roberto Carlos Simões Galvão

    2007-04-01

    Full Text Available In the present article, we propose a brief analysis of Francis Bacon’s thought (1561-1626 and his contributions to the Education. With Bacon, the old religious or metaphysical character of knowledge was substituted by the objectivity of the experimental science, something unknown until then. The science started to represent a means in search of an end, i.e., man’s control over nature. The desire of Bacon to promote a reorganization of the power of the human knowledge, not based on the old scholastic knowledge, but in the new scientific knowledge, was shared by educators, philosophers and statesmen of his time. The role of the school would be to assure the dissemination of this new knowledge which, properly unified, would be within reach of all the children

  12. Experimental vibration level analysis of a Francis turbine

    International Nuclear Information System (INIS)

    Bucur, D M; Dunca, G; Calinoiu, C

    2012-01-01

    In this study the vibration level of a Francis turbine is investigated by experimental work in site. Measurements are carried out for different power output values, in order to highlight the influence of the operation regimes on the turbine behavior. The study focuses on the turbine shaft to identify the mechanical vibration sources and on the draft tube in order to identify the hydraulic vibration sources. Analyzing the vibration results, recommendations regarding the operation of the turbine, at partial load close to minimum values, in the middle of the operating domain or close to maximum values of electric power, can be made in order to keep relatively low levels of vibration. Finally, conclusions are drawn in order to present the real sources of the vibrations.

  13. Simulations of Steady Cavitating Flow in a Small Francis Turbine

    Directory of Open Access Journals (Sweden)

    Ahmed Laouari

    2016-01-01

    Full Text Available The turbulent flow through a small horizontal Francis turbine is solved by means of Ansys-CFX at different operating points, with the determination of the hydrodynamic performance and the best efficiency point. The flow structures at different regimes reveal a large flow eddy in the runner and a swirl in the draft tube. The use of the mixture model for the cavity/liquid two-phase flow allowed studying the influence of cavitation on the hydrodynamic performance and revealed cavitation pockets near the trailing edge of the runner and a cavitation vortex rope in the draft tube. By maintaining a constant dimensionless head and a distributor vane opening while gradually increasing the cavitation number, the output power and efficiency reached a critical point and then had begun to stabilize. The cavitation number corresponding to the safety margin of cavitation is also predicted for this hydraulic turbine.

  14. Prediction of dynamic blade loading of the Francis-99 turbine

    International Nuclear Information System (INIS)

    Nicolle, J; Cupillard, S

    2015-01-01

    CFD simulations focusing on capturing dynamic fluctuations of the flow for three operating points were performed for a scale model of a high head Francis turbine. A mesh sensitivity study showed an influence of the near wall resolution, consequently a low Reynolds mesh with a SST turbulence model was used. Rotor/stator fluctuations are well reproduced with the full turbine simulation at all operating points. Velocity contours and average velocity profiles from LDV measurements in the draft tube confirm that the flow physics is generally well reproduced. Simplified approaches such as profile transform and Fourier transform underestimated the measured fluctuations. As full turbine simulations were time-consuming, a simulation with only the draft tube was performed at part load to predict the fluctuations in the draft tube cone. The SAS-SST turbulence model was able to capture the vortex rope behavior

  15. Trouble Don't Last

    Science.gov (United States)

    Pearsall, Shelley

    2004-01-01

    Even as a child, Pearsall questioned social injustice and prejudice. In her own community in Ohio and, as she grew, all over the world, she saw social inequities she could neither understand nor accept. Her novel "Trouble Don't Last," takes place during the era of the Underground Railroad. The chapter included here pulls us in…

  16. Kulturel liminalitet i Don Quixote

    DEFF Research Database (Denmark)

    Fastrup, Anne

    2007-01-01

    Med udgangspunkt i og i kontrast til nogle af hovedlinierne i den nyere litteratur om Don Quixote søger artiklen tilbage til de mere specifikke og lokale historiske forhold, som er romanens baggrund, bl.a. til Cervantes' »algierske erfaring« med tyrkisk fangenskab. Artiklen forsøger at kombinere ...

  17. State of the art in numerical simulation of high head Francis turbines

    Directory of Open Access Journals (Sweden)

    Trivedi Chirag

    2016-01-01

    Full Text Available The Francis-99 test case consists in a high head Francis turbine model, which geometry together with meshes and detailed experimental measurements is freely available at www.francis-99.org. Three workshops were initially planned to exchange experience on numerical investigations of the test case concerning steady state operating conditions, transient operating conditions and fluid structure analysis. The first workshop was held in Trondheim, Norway in December 2014. Some results of the 14 contributions are presented. They are concerned with the influence of the near wall space discretization and turbulence modelling in order to capture hydraulic efficiency, torque, pressure and velocity with a good uncertainty at three operating conditions.

  18. What Neural Substrates Trigger the Adept Scientific Pattern Discovery by Biologists?

    Science.gov (United States)

    Lee, Jun-Ki; Kwon, Yong-Ju

    2011-04-01

    This study investigated the neural correlates of experts and novices during biological object pattern detection using an fMRI approach in order to reveal the neural correlates of a biologist's superior pattern discovery ability. Sixteen healthy male participants (8 biologists and 8 non-biologists) volunteered for the study. Participants were shown fifteen series of organism pictures and asked to detect patterns amid stimulus pictures. Primary findings showed significant activations in the right middle temporal gyrus and inferior parietal lobule amongst participants in the biologist (expert) group. Interestingly, the left superior temporal gyrus was activated in participants from the non-biologist (novice) group. These results suggested that superior pattern discovery ability could be related to a functional facilitation of the parieto-temporal network, which is particularly driven by the right middle temporal gyrus and inferior parietal lobule in addition to the recruitment of additional brain regions. Furthermore, the functional facilitation of the network might actually pertain to high coherent processing skills and visual working memory capacity. Hence, study results suggested that adept scientific thinking ability can be detected by neuronal substrates, which may be used as criteria for developing and evaluating a brain-based science curriculum and test instrument.

  19. Reliability of the Francis Scale of Attitude Toward Christianity among 8-yr-olds.

    Science.gov (United States)

    Robbins, Mandy; Francis, Leslie J; Williams, Naomi

    2003-02-01

    The Francis Scale of Attitude Toward Christianity was completed by 78 8-yr.-olds (40 boys and 38 girls) whose data support reliability measured as the internal consistency of the scale for this young sample.

  20. The Power of the Word and the Mastery of Nature: Renaissance Magic and Francis Bacon

    Czech Academy of Sciences Publication Activity Database

    Špelda, Daniel

    19/43/, - (2005), s. 7-36. ISBN 80-7007-236-9. ISSN 0231-5955 Institutional research plan: CEZ:AV0Z90090514 Keywords : magic * renaissance philosophy * Francis Bacon Subject RIV: AA - Philosophy ; Religion

  1. Robust Finite-Time Terminal Sliding Mode Control for a Francis Hydroturbine Governing System

    OpenAIRE

    Fengjiao Wu; Junling Ding; Zhengzhong Wang

    2016-01-01

    The robust finite-time control for a Francis hydroturbine governing system is investigated in this paper. Firstly, the mathematical model of a Francis hydroturbine governing system is presented and the nonlinear vibration characteristics are analyzed. Then, on the basis of finite-time control theory and terminal sliding mode scheme, a new robust finite-time terminal sliding mode control method is proposed for nonlinear vibration control of the hydroturbine governing system. Furthermore, the d...

  2. The great war correspondent: Francis McCullagh, 1874–1956

    OpenAIRE

    Horgan, John

    2009-01-01

    Trotsky of Russia knows Francis McCullagh. So does President Calles of Mexico. Peter, the King of Serbia, was McCullagh’s friend. The headhunters of the upper Amazon list Francis McCullagh as one of their principal deities. The warring tribes of Morocco call him blood brother. A room is always ready for him in the imperial palace of Siam. The latchstrings of hundreds of Siberian peasant huts are out in anticipation of his coming.

  3. The Visual Shock of Francis Bacon: An essay in neuroesthetics

    Directory of Open Access Journals (Sweden)

    Semir eZeki

    2013-12-01

    Full Text Available In this paper we discuss the work of Francis Bacon in the context of his declared aim of giving a visual shock. We explore what this means in terms of brain activity and what insights into the brain’s visual perceptive system his work gives. We do so especially with reference to the representation of faces and bodies in the human visual brain. We discuss the evidence that shows that both these categories of stimuli have a very privileged status in visual perception, compared to the perception of other stimuli, including man-made artifacts such as houses, chairs and cars. We show that viewing face and house stimuli that depart significantly from a normal representation of faces and bodies entails a significant difference in the pattern of brain activation. We argue that Bacon succeeded in delivering his visual shock because he subverted the normal neural representation of faces and bodies, without at the same time subverting the representation of man-made artifacts.

  4. Civil history and poetry, certainty and truth in Francis Bacon

    Directory of Open Access Journals (Sweden)

    Silvia Manzo

    2015-02-01

    Full Text Available This article aims at studying key components of Francis Bacon’s theory of history and of his work as practitioner of civil history, particularly in regard to truth and certainty in historical narratives. It compares Bacon’s theories of history and poetry, and the way in which he conceives their relation to certainty, truth and fiction. It analyzes mainly two sorts of writings. On the one hand, it investigates the programmatic texts where Bacon’s views of history and poetry are developed. On the other hand, it examines the finished and unfinished civil histories written by Bacon as historian. In addition, the article evaluates Bacon’s stances against the background of Renaissance and early modern English historiography. It concludes that although history and poetry constitute separate branches in Bacon’s classification of learning, they share important elements, in keeping with the view of poetry maintained by his contemporary Philip Sidney. Thus, Bacon included fictional patterns in his historical narrative and distinguished certainties from conjectures in a particular way. This attitude towards civil history shows a strong contrast to Bacon’s methodology for natural histories, which, in order to reach certainty, staunchly recommends to exclude any fictional narrative in reporting the facts of nature.

  5. The medical philosophy of Francis Bacon (1561-1626).

    Science.gov (United States)

    Boss, J

    1978-01-01

    Francis Bacon's view of man is dualistic but, although he takes note of mental faculties, he makes the relation between mind and body, rather than the substance of mind, the basis for enquiry into mental processes and, more particularly, for the medically relevant study of mind. (He uses "mind" and "soul" as equivalent terms.) The healing of the body requires study of the body, and the ineffectiveness of physicians is due to their failure in this respect rather than to the body's complexity. To learn about the body requires clinical observation and recording, together with the comparison of bodies, experiments on living animals and attention to pathological changes. The aims of medicine should include not only the restoration of health but also the relief of suffering and they are not to be limited by putting aside a disease as incurable. To learn from treatment it must be fixed in its ordering with controlled and limited variation. Bacon has no separation of medicine from natural science; his philosophy of medicine is his general philosophy of the advancement of knowledge, but limited to a particular field of application. If medicine is separated from natural philosophy it is changed wholly or greatly into empiricism.

  6. Computation of Cavitating Flow in a Francis Hydroturbine

    Science.gov (United States)

    Leonard, Daniel; Lindau, Jay

    2013-11-01

    In an effort to improve cavitation characteristics at off-design conditions, a steady, periodic, multiphase, RANS CFD study of an actual Francis hydroturbine was conducted and compared to experimental results. It is well-known that operating hydroturbines at off-design conditions usually results in the formation of large-scale vaporous cavities. These cavities, and their subsequent collapse, reduce efficiency and cause damage and wear to surfaces. The conventional hydro community has expressed interest in increasing their turbine's operating ranges, improving their efficiencies, and reducing damage and wear to critical turbine components. In this work, mixing planes were used to couple rotating and stationary stages of the turbine which have non-multiple periodicity, and provide a coupled solution for the stay vanes, wicket gates, runner blades, and draft tube. The mixture approach is used to simulate the multiphase flow dynamics, and cavitation models were employed to govern the mass transfer between liquid and gas phases. The solution is compared with experimental results across a range of cavitation numbers which display all the major cavitation features in the machine. Unsteady computations are necessary to capture inherently unsteady cavitation phenomena, such as the precessing vortex rope, and the shedding of bubbles from the wicket gates and their subsequent impingement upon the leading edge of the runner blades. To display these features, preliminary unsteady simulations of the full machine are also presented.

  7. Of the Helmholtz Club, South-Californian seedbed for visual and cognitive neuroscience, and its patron Francis Crick.

    Science.gov (United States)

    Aicardi, Christine

    2014-03-01

    Taking up the view that semi-institutional gatherings such as clubs, societies, research schools, have been instrumental in creating sheltered spaces from which many a 20th-century project-driven interdisciplinary research programme could develop and become established within the institutions of science, the paper explores the history of one such gathering from its inception in the early 1980s into the 2000s, the Helmholtz Club, which brought together scientists from such various research fields as neuroanatomy, neurophysiology, psychophysics, computer science and engineering, who all had an interest in the study of the visual system and of higher cognitive functions relying on visual perception such as visual consciousness. It argues that British molecular biologist turned South Californian neuroscientist Francis Crick had an early and lasting influence over the Helmholtz Club of which he was a founding pillar, and that from its inception, the club served as a constitutive element in his long-term plans for a neuroscience of vision and of cognition. Further, it argues that in this role, the Helmholtz Club served many purposes, the primary of which was to be a social forum for interdisciplinary discussion, where 'discussion' was not mere talk but was imbued with an epistemic value and as such, carefully cultivated. Finally, it questions what counts as 'doing science' and in turn, definitions of success and failure-and provides some material evidence towards re-appraising the successfulness of Crick's contribution to the neurosciences. Copyright © 2013 The Author. Published by Elsevier Ltd.. All rights reserved.

  8. Turbulence modeling for Francis turbine water passages simulation

    International Nuclear Information System (INIS)

    Maruzewski, P; Munch, C; Mombelli, H P; Avellan, F; Hayashi, H; Yamaishi, K; Hashii, T; Sugow, Y

    2010-01-01

    The applications of Computational Fluid Dynamics, CFD, to hydraulic machines life require the ability to handle turbulent flows and to take into account the effects of turbulence on the mean flow. Nowadays, Direct Numerical Simulation, DNS, is still not a good candidate for hydraulic machines simulations due to an expensive computational time consuming. Large Eddy Simulation, LES, even, is of the same category of DNS, could be an alternative whereby only the small scale turbulent fluctuations are modeled and the larger scale fluctuations are computed directly. Nevertheless, the Reynolds-Averaged Navier-Stokes, RANS, model have become the widespread standard base for numerous hydraulic machine design procedures. However, for many applications involving wall-bounded flows and attached boundary layers, various hybrid combinations of LES and RANS are being considered, such as Detached Eddy Simulation, DES, whereby the RANS approximation is kept in the regions where the boundary layers are attached to the solid walls. Furthermore, the accuracy of CFD simulations is highly dependent on the grid quality, in terms of grid uniformity in complex configurations. Moreover any successful structured and unstructured CFD codes have to offer a wide range to the variety of classic RANS model to hybrid complex model. The aim of this study is to compare the behavior of turbulent simulations for both structured and unstructured grids topology with two different CFD codes which used the same Francis turbine. Hence, the study is intended to outline the encountered discrepancy for predicting the wake of turbine blades by using either the standard k-ε model, or the standard k-ε model or the SST shear stress model in a steady CFD simulation. Finally, comparisons are made with experimental data from the EPFL Laboratory for Hydraulic Machines reduced scale model measurements.

  9. Turbulence modeling for Francis turbine water passages simulation

    Energy Technology Data Exchange (ETDEWEB)

    Maruzewski, P; Munch, C; Mombelli, H P; Avellan, F [Ecole polytechnique federale de Lausanne, Laboratory of Hydraulic Machines Avenue de Cour 33 bis, CH-1007 Lausanne (Switzerland); Hayashi, H; Yamaishi, K; Hashii, T; Sugow, Y, E-mail: pierre.maruzewski@epfl.c [Nippon KOEI Power Systems, 1-22 Doukyu, Aza, Morijyuku, Sukagawa, Fukushima Pref. 962-8508 (Japan)

    2010-08-15

    The applications of Computational Fluid Dynamics, CFD, to hydraulic machines life require the ability to handle turbulent flows and to take into account the effects of turbulence on the mean flow. Nowadays, Direct Numerical Simulation, DNS, is still not a good candidate for hydraulic machines simulations due to an expensive computational time consuming. Large Eddy Simulation, LES, even, is of the same category of DNS, could be an alternative whereby only the small scale turbulent fluctuations are modeled and the larger scale fluctuations are computed directly. Nevertheless, the Reynolds-Averaged Navier-Stokes, RANS, model have become the widespread standard base for numerous hydraulic machine design procedures. However, for many applications involving wall-bounded flows and attached boundary layers, various hybrid combinations of LES and RANS are being considered, such as Detached Eddy Simulation, DES, whereby the RANS approximation is kept in the regions where the boundary layers are attached to the solid walls. Furthermore, the accuracy of CFD simulations is highly dependent on the grid quality, in terms of grid uniformity in complex configurations. Moreover any successful structured and unstructured CFD codes have to offer a wide range to the variety of classic RANS model to hybrid complex model. The aim of this study is to compare the behavior of turbulent simulations for both structured and unstructured grids topology with two different CFD codes which used the same Francis turbine. Hence, the study is intended to outline the encountered discrepancy for predicting the wake of turbine blades by using either the standard k-{epsilon} model, or the standard k-{epsilon} model or the SST shear stress model in a steady CFD simulation. Finally, comparisons are made with experimental data from the EPFL Laboratory for Hydraulic Machines reduced scale model measurements.

  10. Turbulence modeling for Francis turbine water passages simulation

    Science.gov (United States)

    Maruzewski, P.; Hayashi, H.; Munch, C.; Yamaishi, K.; Hashii, T.; Mombelli, H. P.; Sugow, Y.; Avellan, F.

    2010-08-01

    The applications of Computational Fluid Dynamics, CFD, to hydraulic machines life require the ability to handle turbulent flows and to take into account the effects of turbulence on the mean flow. Nowadays, Direct Numerical Simulation, DNS, is still not a good candidate for hydraulic machines simulations due to an expensive computational time consuming. Large Eddy Simulation, LES, even, is of the same category of DNS, could be an alternative whereby only the small scale turbulent fluctuations are modeled and the larger scale fluctuations are computed directly. Nevertheless, the Reynolds-Averaged Navier-Stokes, RANS, model have become the widespread standard base for numerous hydraulic machine design procedures. However, for many applications involving wall-bounded flows and attached boundary layers, various hybrid combinations of LES and RANS are being considered, such as Detached Eddy Simulation, DES, whereby the RANS approximation is kept in the regions where the boundary layers are attached to the solid walls. Furthermore, the accuracy of CFD simulations is highly dependent on the grid quality, in terms of grid uniformity in complex configurations. Moreover any successful structured and unstructured CFD codes have to offer a wide range to the variety of classic RANS model to hybrid complex model. The aim of this study is to compare the behavior of turbulent simulations for both structured and unstructured grids topology with two different CFD codes which used the same Francis turbine. Hence, the study is intended to outline the encountered discrepancy for predicting the wake of turbine blades by using either the standard k-epsilon model, or the standard k-epsilon model or the SST shear stress model in a steady CFD simulation. Finally, comparisons are made with experimental data from the EPFL Laboratory for Hydraulic Machines reduced scale model measurements.

  11. Glucuronidation of deoxynivalenol (DON) by different animal species: identification of iso-DON glucuronides and iso-deepoxy-DON glucuronides as novel DON metabolites in pigs, rats, mice, and cows.

    Science.gov (United States)

    Schwartz-Zimmermann, Heidi E; Hametner, Christian; Nagl, Veronika; Fiby, Iris; Macheiner, Lukas; Winkler, Janine; Dänicke, Sven; Clark, Erica; Pestka, James J; Berthiller, Franz

    2017-12-01

    The Fusarium mycotoxin deoxynivalenol (DON) is a frequent contaminant of cereal-based food and feed. Mammals metabolize DON by conjugation to glucuronic acid (GlcAc), the extent and regioselectivity of which is species-dependent. So far, only DON-3-glucuronide (DON-3-GlcAc) and DON-15-GlcAc have been unequivocally identified as mammalian DON glucuronides, and DON-7-GlcAc has been proposed as further DON metabolite. In the present work, qualitative HPLC-MS/MS analysis of urine samples of animals treated with DON (rats: 2 mg/kg bw, single bolus, gavage; mice: 1 mg/kg bw, single i.p. injection; pigs: 74 µg/kg bw, single bolus, gavage; cows: 5.2 mg DON/kg dry mass, oral for 13 weeks) revealed additional DON and deepoxy-DON (DOM) glucuronides. To elucidate their structures, DON and DOM were incubated with human (HLM) and rat liver microsomes (RLM). Besides the expected DON/DOM-3- and 15-GlcAc, minor amounts of four DON- and four DOM glucuronides were formed. Isolation and enzymatic hydrolysis of four of these compounds yielded iso-DON and iso-DOM, the identities of which were eventually confirmed by NMR. Incubation of iso-DON and iso-DOM with RLM and HLM yielded two main glucuronides for each parent compound, which were isolated and identified as iso-DON/DOM-3-GlcAc and iso-DON/DOM-8-GlcAc by NMR. Iso-DON-3-GlcAc, most likely misidentified as DON-7-GlcAc in the literature, proved to be a major DON metabolite in rats and a minor metabolite in pigs. In addition, iso-DON-8-GlcAc turned out to be one of the major DON metabolites in mice. DOM-3-GlcAc was the dominant DON metabolite in urine of cows and an important DON metabolite in rat urine. Iso-DOM-3-GlcAc was detected in urine of DON-treated rats and cows. Finally, DON-8,15-hemiketal-8-glucuronide, a previously described by-product of DON-3-GlcAc production by RLM, was identified in urine of DON-exposed mice and rats. The discovery of several novel DON-derived glucuronides in animal urine requires adaptation of

  12. Don Germán

    OpenAIRE

    Juan Luis Mejía

    1991-01-01

    El veranillo de San Juan hace soportable el mediodía. Los "chorros d'oro" inundan de amarillo los antejardines del Prado. Las golondrinas veraneras invaden, al atardecer, los alrededores de la Biblioteca Departamental. Los voceadores de la suerte del paseo Bolívar claman a los cuatro vientos el número que cambiará su destino . Pero algo falta definitivamente en esta Barranquilla. De alguna manera la ciudad ya no es la misma. Falta Don Germán.

  13. [Don Quijote, a lucid mad].

    Science.gov (United States)

    Alonso Fernández, Francisco

    2004-01-01

    The case of a 50-year-old hidalgo who believed to be transformed into a knight-errant named Don Quijote is a megalomaniac systematized delusion of transformation of the self, a delusion of metamorphosis in reference to the patient's own identity. The outward projection of this syndrome produces some delusional misidentifications of others, things and animals and include elements of a persecutory delusion which increase the grandiosity of the self. At the same time the hidalgo was maniac with a pathway of bipolar disorder. The phenomenon of donquijotismo is described as the defence of wasted causes and Sancho Panza as an illiterate Sócrates.

  14. Don Germán

    Directory of Open Access Journals (Sweden)

    Juan Luis Mejía

    1991-01-01

    Full Text Available El veranillo de San Juan hace soportable el mediodía. Los "chorros d'oro" inundan de amarillo los antejardines del Prado. Las golondrinas veraneras invaden, al atardecer, los alrededores de la Biblioteca Departamental. Los voceadores de la suerte del paseo Bolívar claman a los cuatro vientos el número que cambiará su destino . Pero algo falta definitivamente en esta Barranquilla. De alguna manera la ciudad ya no es la misma. Falta Don Germán.

  15. What cell biologists should know about the National Institutes of Health BRAIN Initiative

    OpenAIRE

    Insel, Thomas R.; Koroshetz, Walter

    2015-01-01

    The BRAIN (Brain Research through Advancing Innovative Neurotechnologies) Initiative is an ambitious project to develop innovative tools for a deeper understanding of how the brain functions in health and disease. Early programs in the National Institutes of Health BRAIN Initiative focus on tools for next-generation imaging and recording, studies of cell diversity and cell census, and integrative approaches to circuit function. In all of these efforts, cell biologists can play a leading role.

  16. Five-Item Francis Scale of Attitude toward Christianity: Construct and Nomological Validity and Internal Consistency among Colombian College Students

    Science.gov (United States)

    Ceballos, Guillermo A.; Suescun, Jesus D.; Oviedo, Heidi C.; Herazo, Edwin; Campo-Arias, Adalberto

    2015-01-01

    The Spanish version of the five-item Francis scale of attitude toward Christianity is a refinement of the short version of the Francis scale of attitude toward Christianity. The scale is a good measurement for intrinsic religiosity. It has been applied previously among Colombian adolescent students. The internal consistency and construct and…

  17. 75 FR 80730 - Francis Slakey on Behalf of the American Physical Society; Receipt of Petition for Rulemaking

    Science.gov (United States)

    2010-12-23

    ... [Docket No. PRM-70-9; NRC-2010-0372] Francis Slakey on Behalf of the American Physical Society; Receipt of... the NRC by Francis Slakey on behalf of the American Physical Society (APS). The petition was docketed... that over the next few years, the NRC would be reviewing license applications for new technologies, and...

  18. Microbial biotransformation of DON: molecular basis for reduced toxicity

    Science.gov (United States)

    Pierron, Alix; Mimoun, Sabria; Murate, Leticia S.; Loiseau, Nicolas; Lippi, Yannick; Bracarense, Ana-Paula F. L.; Schatzmayr, Gerd; He, Jian Wei; Zhou, Ting; Moll, Wulf-Dieter; Oswald, Isabelle P.

    2016-07-01

    Bacteria are able to de-epoxidize or epimerize deoxynivalenol (DON), a mycotoxin, to deepoxy-deoxynivalenol (deepoxy-DON or DOM-1) or 3-epi-deoxynivalenol (3-epi-DON), respectively. Using different approaches, the intestinal toxicity of 3 molecules was compared and the molecular basis for the reduced toxicity investigated. In human intestinal epithelial cells, deepoxy-DON and 3-epi-DON were not cytotoxic, did not change the oxygen consumption or impair the barrier function. In intestinal explants, exposure for 4 hours to 10 μM DON induced intestinal lesions not seen in explants treated with deepoxy-DON and 3-epi-DON. A pan-genomic transcriptomic analysis was performed on intestinal explants. 747 probes, representing 323 genes, were differentially expressed, between DON-treated and control explants. By contrast, no differentially expressed genes were observed between control, deepoxy-DON and 3-epi-DON treated explants. Both DON and its biotransformation products were able to fit into the pockets of the A-site of the ribosome peptidyl transferase center. DON forms three hydrogen bonds with the A site and activates MAPKinases (mitogen-activated protein kinases). By contrast deepoxy-DON and 3-epi-DON only form two hydrogen bonds and do not activate MAPKinases. Our data demonstrate that bacterial de-epoxidation or epimerization of DON altered their interaction with the ribosome, leading to an absence of MAPKinase activation and a reduced toxicity.

  19. Educational background and professional participation by federal wildlife biologists: Implications for science, management, and The Wildlife Society

    Science.gov (United States)

    Schmutz, Joel A.

    2002-01-01

    Over 2,000 people are employed in wildlife biology in the United States federal government. The size of this constituency motivated me to examine the amount of formal education federal biologists have received and the extent of continuing education they undertake by reading journals or attending scientific meetings. Most federal biologists who are members of The Wildlife Society (TWS) have a graduate degree. However, one-third have only a Bachelor of Science degree, despite the current trend toward hiring people with graduate degrees. Most federal biologists are not research biologists. Numbers of journals subscribed to was positively related to educational level. Less than one-third of all wildlife biologists employed by the United States Fish and Wildlife Service are members of TWS or subscribe to any of its journals. In contrast, the majority of presenters at the TWS 2000 Annual Conference were research biologists and members of TWS. The failure of many federal wildlife biologists to read scientific literature or attend professional meetings indicates a failure to promote the importance of continuing education in the federal workplace. I identify 2 potential adverse impacts of this failing: an inability to recognize important and relevant scientific contributions and an ineffectiveness in carrying out adaptive management.

  20. “Is that right?” – Don Favareau, Don Corleone & the semiotics of friendship

    DEFF Research Database (Denmark)

    Emmeche, Claus

    2017-01-01

    A chapter commenting specifically on John Poinsot's "Tractatus de Signis", John Deely's interpretation of Poinsot's mentioning of "friendship" as an example of a triadic relation, Don Favareau's contribution to the biosemiotic community, and Don Corleone as a symbol of a different kind of "friend......A chapter commenting specifically on John Poinsot's "Tractatus de Signis", John Deely's interpretation of Poinsot's mentioning of "friendship" as an example of a triadic relation, Don Favareau's contribution to the biosemiotic community, and Don Corleone as a symbol of a different kind...... of "friendship", and generally on the philosophy of friendship....

  1. Fighting for life: Religion and science in the work of fish and wildlife biologists

    Science.gov (United States)

    Geffen, Joel Phillip

    Philosophers, historians, and sociologists of science have argued that it is impossible to separate fact from value. Even so, Americans generally demand that scientists be "objective." No bias is permitted in their work. Religious motivations in particular are widely considered anathema within the halls of science. My dissertation addresses both theoretical and practical aspects concerning objectivity in science through an examination of fish and wildlife biologists. I hypothesized that they use the language of objective science as a tool to convince others to protect habitats and species. Further, I claimed that this "rhetoric of science" is employed either consciously or unconsciously on behalf of personal values, and that religious and/or spiritual values figure significantly among these. Regarding the issue's practical applications, I argued in support of Susan Longino's assertion that while subjective influences exist in science, they do not necessarily indicate that objectivity has been sacrificed. My primary methodology is ethnographic. Thirty-five biologists working in the Pacific Northwest were interviewed during the course of summer 2001. Participant ages ranged from 23 to 78. Both genders were represented, as were various ethnic and cultural backgrounds, including Native American. I used a questionnaire to guide respondents through a consistent set of open-ended queries. I organized their answers under four categories: the true, the good, the beautiful, and the holy. The first three were borrowed from the theoretical writings of philosopher Immanuel Kant. The last came from Rudolf Otto's theological work. These categories provided an excellent analytical framework. I found that the great majority of fish and wildlife biologists strive for objectivity. However, they are also informed by powerful contextual values. These are derived from environmental ethics, aesthetic preferences pertaining to ecosystem appearance and function, and visceral experiences of

  2. Francis Bacon's New Science: Rhetoric and the Transformative Power of Print.

    Science.gov (United States)

    Heckel, David

    The process of projecting textual models onto the phenomenal world began with the invention of writing and accelerated through the manuscript culture of classical antiquity and the Middle Ages into the age of print. In Francis Bacon's work, the book (a metaphor for the phenomenal world) adapted to the demands of the printed text and reflects the…

  3. The Culture of Science and the Rhetoric of Scientism: From Francis Bacon to the Darwin Fish

    Science.gov (United States)

    Lessl, Thomas M.

    2007-01-01

    The culture of modern science continues to establish its public identity by appealing to values and historical conceptions that reflect its appropriation of various religious ideals during its formative period, most especially in the rhetoric of Francis Bacon. These elements have persisted because they continue to achieve similar goals, but the…

  4. Internal consistency of a Spanish translation of the Francis Scale of Attitude Toward Christianity Short Form.

    Science.gov (United States)

    Campo-Arias, Adalberto; Oviedo, Heidi Celina; Díaz, Carmen Elena; Cogollo, Zuleima

    2006-12-01

    This study evaluated the internal consistency of a Spanish version of the short form of the Francis Scale of Attitude Toward Christianity based on responses of 405 Colombian adolescent students ages 13 to 17 years. This translated short-form version of the scale had an internal consistency of .80. This estimate indicates suitable internal consistency reliability for research use in this population.

  5. "Ajaloo lõpp" on lähedal / Francis Fukuyama ; interv. Adam Piore

    Index Scriptorium Estoniae

    Fukuyama, Francis

    2003-01-01

    Ajakirjas Newsweek ilmunud intervjuus vastab filosoof Francis Fukuyama küsimustele 2004. aasta kõige olulisemate probleemide, EL-i, Cancunis toimunud Maailma Kaubandusorganisatsiooni kõneluste, ajaloo lõppu jõudmise, Pakistani presidendile tehtud atentaadi kohta

  6. Power Swing Generated in Francis Turbines by Part Load and Overload Instabilities

    Directory of Open Access Journals (Sweden)

    David Valentín

    2017-12-01

    Full Text Available Hydropower plays a key role in the actual energy market due to its fast response and regulation capacity. In that way, hydraulic turbines are increasingly demanded to work at off-design conditions, where complex flow patterns and cavitation appear, especially in Francis turbines. The draft tube cavitation surge is a hydraulic phenomenon that appears in Francis turbines below and above its Best Efficiency Point (BEP. It is a low frequency phenomenon consisting of a vortex rope in the runner outlet and draft tube, which can become unstable when its frequency coincides with a natural frequency of the hydraulic circuit. At this situation, the output power can significantly swing, endangering the electrical grid stability. This study is focused on the detection of these instabilities in Francis turbines and their relationship with the output power swings. To do so, extensive experimental tests for different operating conditions have been carried out in a large prototype Francis turbine (444 MW of rated power within the frame of the European Project Hyperbole (FP7-ENERGY-2013-1. Several sensors have been installed in the hydraulic circuit (pressure sensors in the draft tube, spiral casing, and penstock, in the rotating and static structures (vibration sensors, proximity probes, and strain gauges in the runner and in the shaft, as well as in the electrical side (output power, intensity, and voltage. Moreover, a numerical Finite Element Method (FEM has been also used to relate the hydraulic excitation with the output power swing.

  7. Francis Farley presenting his novel "Catalysed Fusion" in the CERN Library

    CERN Multimedia

    Farley, Irina

    2013-01-01

    "Catalysed Fusion" is described by its author Francis Farley, 92, as a "true-to-life fantasy woven around particle physics" set in 1980s Geneva – "the city where nations meet and particles collide". Farley presented the book in the program "Literature in Focus" on Tuesday 16th April 2013.

  8. Hydraulic Turbines: The Francis Turbine. Technical Terminology Bulletin. Terminotech, Vol. 2, No. 2.

    Science.gov (United States)

    General Electric Co. of Canada, Ltd., Montreal, Quebec.

    This issue of a bulletin of technological terminology is devoted to the Francis turbine. A brief narrative on the subject is presented in both French and English. An English-French dictionary of terms comprises the bulk of the document. An explanatory illustration is appended. (JB)

  9. Saint Francis Xavier on Jesuit School Stages of the Bohemian Province

    Czech Academy of Sciences Publication Activity Database

    Bobková, Kateřina; Jacková, Magdaléna

    2015-01-01

    Roč. 25, č. 2 (2015), s. 135-155 ISSN 0515-3190 R&D Projects: GA ČR GPP406/12/P823 Institutional support: RVO:68378068 ; RVO:67985963 Keywords : St. Francis Xavier * Jesuit saints * Jesuit theatre * neolatin drama * school theatre * Avancini, Nicolaus * Engel, Arnoldus Subject RIV: AJ - Letters, Mass-media, Audiovision; AB - History (HIU-Y)

  10. Inventing Citizens, Imagining Gender Justice: The Suffrage Rhetoric of Virginia and Francis Minor

    Science.gov (United States)

    Ray, Angela G.; Richards, Cindy Koenig

    2007-01-01

    From the late 1860s through the mid-1870s, woman suffrage activists developed an ingenious legal argument, claiming that the U.S. Constitution already enfranchised women citizens. The argument, first articulated by St. Louis activists Virginia and Francis Minor, precipitated rhetorical performances by movement activists on public platforms and in…

  11. Glade/woodland restoration in the St. Francis Mountain Bird Conservation Area

    Science.gov (United States)

    David A. Hasenbeck

    2007-01-01

    The Missouri Department of Conservation (MDC), the Missouri Department of Natural Resources, the U.S. Forest Service, and American Bird Conservancy, share goals to restore and manage high quality glade, savanna, and woodland habitats within the Saint Francis Bird Conservation Area. The partnership endeavors to maintain and enhance an ecosystem with native glade and...

  12. Validez y confiabilidad de la escala breve de Francis para actitud ante el cristianismo

    Directory of Open Access Journals (Sweden)

    Zuleima Cogollo

    2012-04-01

    Resultados. La escala Francis-5 mostró una estructura unidimensional, con un valor propio de 3,681 que dio cuenta del 73,6% de la varianza. Las mujeres puntuaron significativamente mayor que los varones, 18,5 (DE=2,7 vs. 17,9 (DE=3,3 (t = 4,3; p

  13. 78 FR 59913 - Revision of the Land Management Plan for the Francis Marion National Forest

    Science.gov (United States)

    2013-09-30

    ... telecommunication devices for the deaf (TDD) may call the Federal Information Relay Service (FIRS) at 1-800- 877... planning process can also be found on the Francis Marion National Forest Web site at www.fs.usda.gov/goto/scnfs/fmplan . SUPPLEMENTARY INFORMATION: Pursuant to the 2012 Forest Planning Rule (36 CFR Part 219...

  14. Hydrologic and water quality monitoring on Turkey Creek watershed, Francis Marion National Forest, SC

    Science.gov (United States)

    D.M. Amatya; T.J. Callahan; A. Radecki-Pawlik; P. Drewes; C. Trettin; W.F. Hansen

    2008-01-01

    The re-initiation of a 7,260 ha forested watershed study on Turkey Creek, a 3rd order stream, within the Francis Marion National forest in South Carolina, completes the development of a multi-scale hydrology and ecosystem monitoring framework in the Atlantic Coastal Plain. Hydrology and water quality monitoring began on the Santee Experimental...

  15. Don Zhuanu otdajutsja tolko po ljubvi

    Index Scriptorium Estoniae

    2006-01-01

    Eestisse tuleb külla Roman Viktjuki Teater, 1. nov. mängitakse Vene Kultuurikeskuses Jean Genet' "Toatüdrukuid" (lavastaja Roman Viktjuk), 23. nov. etendatakse Eric-Emmanuel Scmitti "Don Juani viimast armastust" (lavastaja Roman Viktjuk)

  16. Don't Take This with That!

    Medline Plus

    Full Text Available ... Tobacco Products Drugs Home Drugs Resources for You Special Features Don't take this with that! Share ... Drug Interactions: What You Should Know More in Special Features Page Last Updated: 12/17/2015 Note: ...

  17. Demystifying animal 'personality' (or not): why individual variation matters to experimental biologists.

    Science.gov (United States)

    Roche, Dominique G; Careau, Vincent; Binning, Sandra A

    2016-12-15

    Animal 'personality', defined as repeatable inter-individual differences in behaviour, is a concept in biology that faces intense controversy. Critics argue that the field is riddled with terminological and methodological inconsistencies and lacks a sound theoretical framework. Nevertheless, experimental biologists are increasingly studying individual differences in physiology and relating these to differences in behaviour, which can lead to fascinating insights. We encourage this trend, and in this Commentary we highlight some of the benefits of estimating variation in (and covariation among) phenotypic traits at the inter- and intra-individual levels. We focus on behaviour while drawing parallels with physiological and performance-related traits. First, we outline some of the confusion surrounding the terminology used to describe repeatable inter-individual differences in behaviour. Second, we argue that acknowledging individual behavioural differences can help researchers avoid sampling and experimental bias, increase explanatory power and, ultimately, understand how selection acts on physiological traits. Third, we summarize the latest methods to collect, analyse and present data on individual trait variation. We note that, while measuring the repeatability of phenotypic traits is informative in its own right, it is only the first step towards understanding how natural selection and genetic architecture shape intra-specific variation in complex, labile traits. Thus, understanding how and why behavioural traits evolve requires linking repeatable inter-individual behavioural differences with core aspects of physiology (e.g. neurophysiology, endocrinology, energy metabolism) and evolutionary biology (e.g. selection gradients, heritability). © 2016. Published by The Company of Biologists Ltd.

  18. How in the 20th century physicists, chemists and biologists answered the question: what is life?

    International Nuclear Information System (INIS)

    Reutov, Valentin P; Schechter, A N

    2010-01-01

    The most essential achievements in 20th century biology are analyzed and the question of how throughout the last century physicists, chemists and biologists answered the question 'What is life?' is considered. The most considerable scientific achievement of 20th century biology, and perhaps of all science, is considered by many to be the discovery by biologist J Watson and physicists F Crick and M Wilkins that resulted in establishing the DNA structure. The related work of well-known scientists of the USA and Europe, E Schroedinger, L Pauling, M Perutz, J Kendrew, and of the Russian scientists N K Koltsov, N V Timofeeff-Ressovsky, G A Gamow, A M Olovnikov, is analyzed. Presently, when the structure of DNA, the process of gene expression and even the genomes of human beings are already known, scientists realize that we still do not know many of the most important things. In our opinion, the 20th century studies of nucleic acids largely ignored the principle of the cyclic organisation of DNA. In this connection, we analyze the principle of cyclicity, which in its generality may well complement the concept of the atomic structure of matter. (from the history of physics)

  19. How in the 20th century physicists, chemists and biologists answered the question: what is life?

    Energy Technology Data Exchange (ETDEWEB)

    Reutov, Valentin P [Institute for Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow (Russian Federation); Schechter, A N [National Institutes of Health, Bethesda, Maryland (United States)

    2010-07-08

    The most essential achievements in 20th century biology are analyzed and the question of how throughout the last century physicists, chemists and biologists answered the question 'What is life?' is considered. The most considerable scientific achievement of 20th century biology, and perhaps of all science, is considered by many to be the discovery by biologist J Watson and physicists F Crick and M Wilkins that resulted in establishing the DNA structure. The related work of well-known scientists of the USA and Europe, E Schroedinger, L Pauling, M Perutz, J Kendrew, and of the Russian scientists N K Koltsov, N V Timofeeff-Ressovsky, G A Gamow, A M Olovnikov, is analyzed. Presently, when the structure of DNA, the process of gene expression and even the genomes of human beings are already known, scientists realize that we still do not know many of the most important things. In our opinion, the 20th century studies of nucleic acids largely ignored the principle of the cyclic organisation of DNA. In this connection, we analyze the principle of cyclicity, which in its generality may well complement the concept of the atomic structure of matter. (from the history of physics)

  20. BioSPICE: access to the most current computational tools for biologists.

    Science.gov (United States)

    Garvey, Thomas D; Lincoln, Patrick; Pedersen, Charles John; Martin, David; Johnson, Mark

    2003-01-01

    The goal of the BioSPICE program is to create a framework that provides biologists access to the most current computational tools. At the program midpoint, the BioSPICE member community has produced a software system that comprises contributions from approximately 20 participating laboratories integrated under the BioSPICE Dashboard and a methodology for continued software integration. These contributed software modules are the BioSPICE Dashboard, a graphical environment that combines Open Agent Architecture and NetBeans software technologies in a coherent, biologist-friendly user interface. The current Dashboard permits data sources, models, simulation engines, and output displays provided by different investigators and running on different machines to work together across a distributed, heterogeneous network. Among several other features, the Dashboard enables users to create graphical workflows by configuring and connecting available BioSPICE components. Anticipated future enhancements to BioSPICE include a notebook capability that will permit researchers to browse and compile data to support model building, a biological model repository, and tools to support the development, control, and data reduction of wet-lab experiments. In addition to the BioSPICE software products, a project website supports information exchange and community building.

  1. Don\\'t Ask, Don\\'t Tell: Ethical Issues Concerning Learning and ...

    African Journals Online (AJOL)

    Informed consent procedures and requirements must be clearly established and communicated. The learning and proficiency practices should be restricted to the staff that can truly benefit from the experience. The practice of 'don't ask, don't tell' is not an option. South African Journal of Family Practice Vol. 50 (4) 2008: pp.

  2. Guidelines : the do's, don'ts and don't knows of feedback for clinical education

    NARCIS (Netherlands)

    Lefroy, Janet; Watling, Chris; Teunissen, Pim W; Brand, Paul

    2015-01-01

    INTRODUCTION: The guidelines offered in this paper aim to amalgamate the literature on formative feedback into practical Do's, Don'ts and Don't Knows for individual clinical supervisors and for the institutions that support clinical learning. METHODS: The authors built consensus by an iterative

  3. The Internal Consistency Reliability of the Katz-Francis Scale of Attitude toward Judaism among Australian Jews

    Directory of Open Access Journals (Sweden)

    Patrick Lumbroso

    2016-09-01

    Full Text Available The Katz-Francis Scale of Attitude toward Judaism was developed initially to extend among the Hebrew-speaking Jewish community in Israel a growing body of international research concerned to map the correlates, antecedents and consequences of individual differences in attitude toward religion as assessed by the Francis Scale of Attitude toward Christianity. The present paper explored the internal consistency reliability and construct validity of the English translation of the Katz-Francis Scale of Attitude toward Judaism among 101 Australian Jews. On the basis of these data, this instrument is commended for application in further research.

  4. Buscando a don Claudio Moyano

    Directory of Open Access Journals (Sweden)

    Juan González Ruiz

    2009-12-01

    Full Text Available (ES En el primer número de esta revista digital "Cabás", Antonio Montero Alcalde hizo un pormenorizado y útil análisis de la llamada Ley Moyano, la Ley de Instrucción Pública promulgada en 1857; la importancia de este texto legal en el desarrollo de la educación en España a lo largo de más de un siglo ha sido puesta de relieve en multitud de estudios históricos referidos a la época contemporánea. Nacido en una pequeña población zamorana el día 30 de octubre de 1809, la vida pública de don Claudio Moyano Samaniego, el firmante de la ley que lleva su nombre, se desarrolló básicamente en la corte madrileña; no obstante, rastrear en el entorno de su tierra natal algunos aspectos y circunstancias de su persona puede tener interés para completar la figura de una personalidad tan citada por su obra como desconocida por su vida. Y, al menos, sirve como curioso entretenimiento de un impenitente viajero a la búsqueda de huellas históricas de las escuelas de otros tiempos y de los hombres dedicados a ellas.

  5. Values and attitudes of National Wildlife Refuge managers and biologists; Report to respondents

    Science.gov (United States)

    Brinson, Ayeisha A.; Benson, Delwin E.

    2002-01-01

    The issues affecting natural resource management, the society in which natural resource management occurs, natural resource agency personnel, and the publics they serve have changed in recent decades. Previous studies of Refuge professionals in the U.S. Fish and Wildlife Service (Service) have revealed that employees lack strong commitment to the current organizational structure, were frustrated with the lack of communication within the agency and felt there was a need for strong leadership (PEER 1998, 1999). These results prompted the authors to have further questions about refuge management in the Fish and Wildlife Service. What do employees value about their agency? Is there a difference in values between refuge managers and biologists and if so, what are those differences and what influences those differences?

  6. GeneNotes – A novel information management software for biologists

    Directory of Open Access Journals (Sweden)

    Wong Wing H

    2005-02-01

    Full Text Available Abstract Background Collecting and managing information is a challenging task in a genome-wide profiling research project. Most databases and online computational tools require a direct human involvement. Information and computational results are presented in various multimedia formats (e.g., text, image, PDF, word files, etc., many of which cannot be automatically processed by computers in biologically meaningful ways. In addition, the quality of computational results is far from perfect and requires nontrivial manual examination. The timely selection, integration and interpretation of heterogeneous biological information still heavily rely on the sensibility of biologists. Biologists often feel overwhelmed by the huge amount of and the great diversity of distributed heterogeneous biological information. Description We developed an information management application called GeneNotes. GeneNotes is the first application that allows users to collect and manage multimedia biological information about genes/ESTs. GeneNotes provides an integrated environment for users to surf the Internet, collect notes for genes/ESTs, and retrieve notes. GeneNotes is supported by a server that integrates gene annotations from many major databases (e.g., HGNC, MGI, etc.. GeneNotes uses the integrated gene annotations to (a identify genes given various types of gene IDs (e.g., RefSeq ID, GenBank ID, etc., and (b provide quick views of genes. GeneNotes is free for academic usage. The program and the tutorials are available at: http://bayes.fas.harvard.edu/genenotes/. Conclusions GeneNotes provides a novel human-computer interface to assist researchers to collect and manage biological information. It also provides a platform for studying how users behave when they manipulate biological information. The results of such study can lead to innovation of more intelligent human-computer interfaces that greatly shorten the cycle of biology research.

  7. Internal consistency of a five-item form of the Francis Scale of Attitude Toward Christianity among adolescent students.

    Science.gov (United States)

    Campo-Arias, Adalberto; Oviedo, Heidi Celina; Cogollo, Zuleima

    2009-04-01

    The short form of the Francis Scale of Attitude Toward Christianity (L. J. Francis, 1992) is a 7-item Likert-type scale that shows high homogeneity among adolescents. The psychometric performance of a shorter version of this scale has not been explored. The authors aimed to determine the internal consistency of a 5-item form of the Francis Scale of Attitude Toward Christianity among 405 students from a school in Cartagena, Colombia. The authors computed the Cronbach's alpha coefficient for the 5 items with a greater corrected item-total punctuation correlation. The version without Items 2 and 7 showed internal consistency of .87. The 5-item version of the Francis Scale of Attitude Toward Christianity exhibited higher internal consistency than did the 7-item version. Future researchers should corroborate this finding.

  8. Effects of draft tube on the hydraulic performance of a Francis turbine

    International Nuclear Information System (INIS)

    Jeon, J H; Byeon, S S; Kim, Y J

    2013-01-01

    The draft tube is an important component of a Francis turbine which influences the hydraulic performance. It is located just under the runner and allowed to decelerate the flow velocity exiting the runner, thereby converting the excess of kinetic energy into static pressure. In this study, we have numerically investigated the hydraulic performance of a Francis turbine on the 15MW hydropower generation with various design parameters (three types of draft tube, thickness of guide vane) through a three-dimensional numerical method with the SST turbulent model. The vortex rope characteristics of the draft tube were confirmed. The results of the vortex flow fields and flow characteristics were graphically depicted with different design parameters and operating conditions

  9. Robust Finite-Time Terminal Sliding Mode Control for a Francis Hydroturbine Governing System

    Directory of Open Access Journals (Sweden)

    Fengjiao Wu

    2016-01-01

    Full Text Available The robust finite-time control for a Francis hydroturbine governing system is investigated in this paper. Firstly, the mathematical model of a Francis hydroturbine governing system is presented and the nonlinear vibration characteristics are analyzed. Then, on the basis of finite-time control theory and terminal sliding mode scheme, a new robust finite-time terminal sliding mode control method is proposed for nonlinear vibration control of the hydroturbine governing system. Furthermore, the designed controller has good robustness which could resist external random disturbances. Numerical simulations are employed to verify the effectiveness and superiority of the designed finite-time sliding mode control scheme. The approach proposed in this paper is simple and also provides a reference for relevant hydropower systems.

  10. Experimental investigations of the unsteady flow in a Francis turbine draft tube cone

    International Nuclear Information System (INIS)

    Baya, A; Muntean, S; Campian, V C; Cuzmos, A; Diaconescu, M; Balan, G

    2010-01-01

    Operating Francis turbines at partial discharge is often hindered by the development of the helical vortex (so-called vortex rope) downstream the runner, in the draft tube cone. The unsteady pressure field induced by precessing vortex rope leads to pressure fluctuations. The paper presents the experimental investigations of the unsteady pressure field generated by precessing vortex rope and its associated pressure fluctuations into a draft tube of the Francis turbine operating at partial discharge. In situ measurements are performed in order to evaluate the pressure fluctuations and vortex rope frequency at partial load operation. Three pressure taps are installed on the cone wall of the draft tube in order to record the unsteady pressure. As a result, the Fourier spectra are obtained in order to evaluate the amplitude of pressure fluctuations and vortex rope frequency. Moreover, the wall pressure recovery along to the draft tube cone is acquired. Finally, conclusions are drawn in order to present the vortex rope effects.

  11. Experimental investigations of the unsteady flow in a Francis turbine draft tube cone

    Energy Technology Data Exchange (ETDEWEB)

    Baya, A [Department of Hydraulic Machinery, ' Politehnica' University of Timisoara Bv. Mihai Viteazu 1, RO-300222, Timisoara (Romania); Muntean, S [Centre of Advanced Research in Engineering Sciences, Romanian Academy - Timisoara Branch Bv. Mihai Viteazu 24, RO-300223, Timisoara (Romania); Campian, V C; Cuzmos, A [Research Center in Hydraulics, Automation and Heat Transfer, ' Eftimie Murgu' University of Resita P-ta. Traian Vuia 1-4, RO-320085, Resita (Romania); Diaconescu, M; Balan, G, E-mail: abaya@mh.mec.upt.r [Ramnicu Valcea Subsidiary, S.C. Hidroelectrica S.A. Str. Decebal 11, RO-240255, Ramnicu Valcea (Romania)

    2010-08-15

    Operating Francis turbines at partial discharge is often hindered by the development of the helical vortex (so-called vortex rope) downstream the runner, in the draft tube cone. The unsteady pressure field induced by precessing vortex rope leads to pressure fluctuations. The paper presents the experimental investigations of the unsteady pressure field generated by precessing vortex rope and its associated pressure fluctuations into a draft tube of the Francis turbine operating at partial discharge. In situ measurements are performed in order to evaluate the pressure fluctuations and vortex rope frequency at partial load operation. Three pressure taps are installed on the cone wall of the draft tube in order to record the unsteady pressure. As a result, the Fourier spectra are obtained in order to evaluate the amplitude of pressure fluctuations and vortex rope frequency. Moreover, the wall pressure recovery along to the draft tube cone is acquired. Finally, conclusions are drawn in order to present the vortex rope effects.

  12. On the centenary of the birth of Francis H. C. Crick - from physics to genetics and neuroscience.

    Science.gov (United States)

    Teive, Hélio A G

    2016-04-01

    The year 2016 marks the centenary of the birth of Francis Crick (1916-2004), who made outstanding contributions to genetics and neuroscience. In 1953, in a collaborative study, Francis Crick and James Watson discovered the DNA double helix, and in 1962 they and Maurice Wilkins were awarded the Noble Prize in Physiology or Medicine. Crick subsequently became very interested in neuroscience, particularly consciousness and its relationship to the claustrum, a small gray matter structure between the insula and putamen.

  13. Psychometric properties of the Francis Scale of Attitude Towards Christianity among Portuguese university students.

    Science.gov (United States)

    Ferreira, Ana Veríssimo; Neto, Félix

    2002-12-01

    To facilitate use of the adult form of the Francis Scale of Attitude Towards Christianity in cross-cultural studies, the psychometric characteristics of the translated scale were examined among 323 university students in Portugal (130 men and 193 women). Their ages ranged from 18 to 31 years. Analysis supported the unidimensionality, internal consistency, and construct validity of this scale in this sample of Portuguese university students.

  14. The Norwegian translation of the Francis Scale of Attitude toward Christianity.

    Science.gov (United States)

    Francis, Leslie J; Enger, Trond

    2002-12-01

    This paper reviews the development of the Francis Scale of Attitude toward Christianity and then examines the psychometric properties of the Norwegian translation of this instrument among a sample of 479 young people between the ages of 11 and 18 years attending secondary school. The data support the reliability of this instrument and commend it for further validation studies and for wider general use among young people in Norway.

  15. Assessing clergy work-related psychological health : reliability and validity of the Francis Burnout Inventory

    OpenAIRE

    Francis, Leslie J.; Laycock, Patrick; Crea, Giuseppe

    2017-01-01

    Drawing on the classic model of balanced affect, the Francis Burnout Inventory (FBI) conceptualised good work-related psychological health among clergy in terms of negative affect being balanced by positive affect. In the FBI negative affect is assessed by the Scale of Emotional Exhaustion in Ministry (SEEM) and positive affect is assessed by the Satisfaction in Ministry Scale (SIMS). In support of the idea of balanced affect, previous work had shown a significant interaction between the effe...

  16. The calculation of fluid-structure interaction and fatigue analysis for Francis turbine runner

    International Nuclear Information System (INIS)

    Wang, X F; Li, H L; Zhu, F W

    2012-01-01

    Francis turbine, as a widely used hydro turbine, is especially suited for the hydropower station with high hydraulic head and higher hydraulic head. For such turbine generator units all around the world, the crack streaks usually come out after a long time use and the resulted accidents may cause huge losses. Hence, it is meaningful to refine the design assuring the stability and safety of the Francis turbine. In this paper, the stiffness and strength as well as the fatigue life of the Francis turbine are studied. Concerning on the turbine of one certain hydropower station, the flow field inside the turbine are first simulated and the pressure distribution around the blades are derived. Meanwhile, the stress distributions of the blades are also obtained. Based on these, the fatigue analyses are applied on the turbine. According to the results of fatigue analyses, some optimal designs on the turbine are verified. The results show that with the optimal designs, the hydraulic performances of the turbine do not change too much while the maximum stress on the turbine decrease and the fatigue life increase as well.

  17. Hydroacoustic simulation of rotor-stator interaction in resonance conditions in Francis pump-turbine

    International Nuclear Information System (INIS)

    Nicolet, C; Ruchonnet, N; Alligne, S; Avellan, F; Koutnik, J

    2010-01-01

    Combined effect of rotating pressure field related to runner blade and wakes of wicket gates leads to rotor stator interactions, RSI, in Francis pump-turbines. These interactions induce pressures waves propagating in the entire hydraulic machine. Superposition of those pressure waves may result in standing wave in the spiral casing and rotating diametrical mode in the guide vanes and can cause strong pressure fluctuations and vibrations. This paper presents the modeling, simulation and analysis of Rotor-Stator Interaction of a scale model of a Francis pump-turbine and related test rig using a one-dimensional approach. The hydroacoustic modeling of the Francis pump-turbine takes into account the spiral casing, the 20 guide vanes, the 9 rotating runner vanes. The connection between stationary and rotating parts is ensured by a valve network driven according to the unsteady flow distribution between guide vanes and runner vanes. Time domain simulations are performed for 2 different runner rotational speeds in turbine mode. The simulation results are analyzed in frequency domain and highlights hydroacoustic resonance between RSI excitations and the spiral case. Rotating diametrical mode in the vaneless gap and standing wave in the spiral case are identified. The influence of the resonance on phase and amplitude of pressure fluctuations obtained for both the spiral case and the vaneless gap is analyzed. The mode shape and frequencies are confirmed using eigenvalues analysis.

  18. Genio y figura de don Alfonso Reyes

    Directory of Open Access Journals (Sweden)

    Eduardo Carranza

    1968-04-01

    Full Text Available Entre varias, escojo esta: por sobria y conmovida a un tiempo. La escribió Juan Fernández Figueroa para su revista " Indice", de Madrid. Nos parece ver a don Alfonso en el rellano de la escalera -al fondo, sus libros; más allá, toda su vida, noble y pura- nos parece verle por última vez, inclinado ya sobre la baranda de la muerte. Tiene la calidad y el dinamismo de unos cuantos dibujos rápidos, nerviosos, esta imagen última de don Alfonso Reyes.

  19. Stability of DON and DON-3-glucoside during baking as affected by the presence of food additives.

    Science.gov (United States)

    Vidal, Arnau; Sanchis, Vicente; Ramos, Antonio J; Marín, Sonia

    2018-03-01

    The mycotoxin deoxynivalenol (DON) is one of the most common mycotoxins of cereals worldwide, and its occurrence has been widely reported in raw wheat. The free mycotoxin form is not the only route of exposure; modified forms can also be present in cereal products. Deoxynivalenol-3-glucoside (DON-3-glucoside) is a common DON plant conjugate. The mycotoxin concentration could be affected by food processing; here, we studied the stability of DON and DON-3-glucoside during baking of small doughs made from white wheat flour and other ingredients. A range of common food additives and ingredients were added to assess possible interference: ascorbic acid (E300), citric acid (E330), sorbic acid (E200), calcium propionate (E282), lecithin (E322), diacetyltartaric acid esters of fatty acid mono- and diglycerides (E472a), calcium phosphate (E341), disodium diphosphate (E450i), xanthan gum (E415), polydextrose (E1200), sorbitol (E420i), sodium bicarbonate (E500i), wheat gluten and malt flour. The DON content was reduced by 40%, and the DON-3-glucoside concentration increased by >100%, after baking for 20 min at 180°C. This confirmed that DON and DON-3-glucoside concentrations can vary during heating, and DON-3-glucoside could even increase after baking. However, DON and DON-3-glucoside are not affected significantly by the presence of the food additives tested.

  20. The rise of repeal: policy entrepreneurship and Don't Ask, Don't Tell.

    Science.gov (United States)

    Neff, Christopher L; Edgell, Luke R

    2013-01-01

    We report on policy entrepreneurship by Servicemembers Legal Defense Network (SLDN) and how its legislative strategies used mini-windows of opportunity to shift Capitol Hill perspectives of Don't Ask, Don't Tell (DADT) from political plutonium to an emerging issue requiring a second look. Four phases in the legislative history of DADT are identified: radioactive, contested, emerging, and viable. In all, this article argues that SLDN's entrepreneurship focused on contesting congressional sensibilities to wait or defer on repeal, maintained that every discharge was damaging and transitioned toward a post-repeal mind set. Finally, we illustrate the importance of these transitions by comparing SLDN's 2004 estimated vote count for the introduction of the Military Readiness Enhancement Act with the final 2010 voting results on the Don't Ask, Don't Tell Repeal Act.

  1. Guidelines: the do's, don'ts and don't knows of feedback for clinical education.

    Science.gov (United States)

    Lefroy, Janet; Watling, Chris; Teunissen, Pim W; Brand, Paul

    2015-12-01

    The guidelines offered in this paper aim to amalgamate the literature on formative feedback into practical Do's, Don'ts and Don't Knows for individual clinical supervisors and for the institutions that support clinical learning. The authors built consensus by an iterative process. Do's and Don'ts were proposed based on authors' individual teaching experience and awareness of the literature, and the amalgamated set of guidelines were then refined by all authors and the evidence was summarized for each guideline. Don't Knows were identified as being important questions to this international group of educators which if answered would change practice. The criteria for inclusion of evidence for these guidelines were not those of a systematic review, so indicators of strength of these recommendations were developed which combine the evidence with the authors' consensus. A set of 32 Do and Don't guidelines with the important Don't Knows was compiled along with a summary of the evidence for each. These are divided into guidelines for the individual clinical supervisor giving feedback to their trainee (recommendations about both the process and the content of feedback) and guidelines for the learning culture (what elements of learning culture support the exchange of meaningful feedback, and what elements constrain it?) Feedback is not easy to get right, but it is essential to learning in medicine, and there is a wealth of evidence supporting the Do's and warning against the Don'ts. Further research into the critical Don't Knows of feedback is required. A new definition is offered: Helpful feedback is a supportive conversation that clarifies the trainee's awareness of their developing competencies, enhances their self-efficacy for making progress, challenges them to set objectives for improvement, and facilitates their development of strategies to enable that improvement to occur.

  2. Don't Take This with That!

    Medline Plus

    Full Text Available ... Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Tobacco Products Drugs Home Drugs Resources for You Special Features Don't take ... worth the squeeze…especially when combining grapefruit with medicines. While it can be part of a balanced ...

  3. Don't Take This with That!

    Medline Plus

    Full Text Available ... Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Tobacco Products Drugs Home Drugs Resources for You Special Features Don't take ... more than fifty prescription and over-the-counter drugs known to the U.S. Food and Drug Administration ...

  4. Don Quijote en Canadá

    Directory of Open Access Journals (Sweden)

    Cristina Botella González

    2007-01-01

    Full Text Available Conocer a Cervantes y su obra.- Descubrir otros países y artistas.- Conocer al personaje de Don Quijote.- Familiarizarse con los personajes principales.- Relacionar la pintura y la literatura.- Desarrollar habilidades manuales y artísticas.- Potenciar la creatividad.

  5. Don't Take This with That!

    Medline Plus

    Full Text Available ... Submit search Popular Content Home Food Drugs Medical Devices Radiation-Emitting Products Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Tobacco Products Drugs Home Drugs Resources for You Special Features Don't take this with that! Share Tweet Linkedin Pin it ...

  6. Don't Take This with That!

    Medline Plus

    Full Text Available ... Español Search FDA Submit search Popular Content Home Food Drugs Medical Devices Radiation-Emitting Products Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Tobacco Products Drugs Home Drugs Resources for You Special Features Don't ...

  7. Dewey or Don't We?

    Science.gov (United States)

    Pendergrass, Devona J.

    2013-01-01

    "Dewey or don't we?" is the question that hundreds, if not thousands, of school librarians across the country are currently asking themselves. Do they throw out what is old but trusted for new organizational systems, or do they continue using the Dewey Decimal Classification (DDC) system and make changes and adjustments to the…

  8. Cervantes and the Lirical Poetry: Don Quixote

    Directory of Open Access Journals (Sweden)

    Fernando Romo Feito

    2012-12-01

    Full Text Available This essay examines the lyrical poems included in the first and the second part of Don Quixote. The different classes of poems are studied attending to its narrative context. But the poetry is also studied by relating it with metrical and aesthetical categories: Realism, Parody, Manierism…

  9. Dos obras del escultor neoclásico inglés John Francis (1780- 1861 en una colección particular española

    Directory of Open Access Journals (Sweden)

    Quintanilla Martínez, Emilio

    2012-09-01

    Full Text Available Two previously unknown works by the British neoclassical sculptor John Francis dating from the second quarter of the 19th century, representing the 1st Duke of Sutherland and, most likely, the sculptor Sir John Francis, have been located in a Spanish private collection.

    Dos obras, hasta ahora inéditas, del escultor neoclásico inglés John Francis del segundo cuarto del siglo XIX, y que representan al primer duque de Sutherland y seguramente al escultor Sir John Francis, en colección privada española.

  10. Simple heuristics and rules of thumb: where psychologists and behavioural biologists might meet.

    Science.gov (United States)

    Hutchinson, John M C; Gigerenzer, Gerd

    2005-05-31

    The Centre for Adaptive Behaviour and Cognition (ABC) has hypothesised that much human decision-making can be described by simple algorithmic process models (heuristics). This paper explains this approach and relates it to research in biology on rules of thumb, which we also review. As an example of a simple heuristic, consider the lexicographic strategy of Take The Best for choosing between two alternatives: cues are searched in turn until one discriminates, then search stops and all other cues are ignored. Heuristics consist of building blocks, and building blocks exploit evolved or learned abilities such as recognition memory; it is the complexity of these abilities that allows the heuristics to be simple. Simple heuristics have an advantage in making decisions fast and with little information, and in avoiding overfitting. Furthermore, humans are observed to use simple heuristics. Simulations show that the statistical structures of different environments affect which heuristics perform better, a relationship referred to as ecological rationality. We contrast ecological rationality with the stronger claim of adaptation. Rules of thumb from biology provide clearer examples of adaptation because animals can be studied in the environments in which they evolved. The range of examples is also much more diverse. To investigate them, biologists have sometimes used similar simulation techniques to ABC, but many examples depend on empirically driven approaches. ABC's theoretical framework can be useful in connecting some of these examples, particularly the scattered literature on how information from different cues is integrated. Optimality modelling is usually used to explain less detailed aspects of behaviour but might more often be redirected to investigate rules of thumb.

  11. Ballooning for Biologists: Mission Essentials for Flying Experiments on Large NASA Balloons

    Science.gov (United States)

    Smith, David J.; Sowa, Marianne

    2017-01-01

    Despite centuries of scientific balloon flights, only a handful of experiments have produced biologically-relevant results. Yet unlike orbital spaceflight, it is much faster and cheaper to conduct biology research with balloons, sending specimens to the near space environment of Earths stratosphere. Samples can be loaded the morning of a launch and sometimes returned to the laboratory within one day after flying. The National Aeronautics and Space Administration (NASA) flies large, unmanned scientific balloons from all over the globe, with missions ranging from hours to weeks in duration. A payload in the middle portion of the stratosphere (approx. 35 km above sea level) will be exposed to an environment similar to the surface of Mars: temperatures generally around -36 C, atmospheric pressure at a thin 1 kPa, relative humidity levels <1%, and a harsh illumination of ultraviolet (UV) and cosmic radiation levels (about 100 W/sq m and 0.1 mGy/d, respectively) that can be obtained nowhere else on the surface of the Earth, including environmental chambers and particle accelerator facilities attempting to simulate space radiation effects. Considering the operational advantages of ballooning and the fidelity of space-like stressors in the stratosphere, researchers in aerobiology, astrobiology, and space biology can benefit from balloon flight experiments as an intermediary step on the extraterrestrial continuum (ground, low Earth orbit, and deep space studies). Our presentation targets biologists with no background or experience in scientific ballooning. We will provide an overview of large balloon operations, biology topics that can be uniquely addressed in the stratosphere, and a roadmap for developing payloads to fly with NASA.

  12. A Song in the Dark. Francis of Assisi’s Canticle of Brother Sun

    Directory of Open Access Journals (Sweden)

    Speelman Willem Marie

    2016-10-01

    Full Text Available The Canticle of the Creatures or Canticle of Brother Sun is based on a particular way of perceiving reality. Francis, who had turned away from ‘the world’, discovered a different way of looking at it. This is a divine way of perceiving, in which the senses do not grasp reality, but accept it as it communicates itself. This way of perceiving is only possible if one does not attempt to master the environment, but allows one’s senses to be weak. It is significant, therefore, that this song of praise was born at a moment of the utmost despair and weakness. The song’s content is in line with this weak perception: it is not about Francis who praises God and (or for His creatures, but rather it is a testimony that the creatures-the elements-are already praising God, and a prayer that He should let Himself be praised by the creatures. Also in line with this weak perception is the fact that the creatures are praised just as they communicate themselves to Francis: as bodies. The theology of this song is that the creatures through their bodies resonate (strengthen, and colour the blessings that come from God, thereby making His blessing present here on earth. Francis’ role is to give a voice and a language to the heavenly praises as they resound in his environment. The transformative power of this song is that we, whether consciously or not, do the same thing when we participate in this song.

  13. Francis Bacon's Valerius Terminus and the Voyage to the "Great Instauration".

    Science.gov (United States)

    Serjeantson, Richard

    2017-01-01

    Francis Bacon's earliest surviving natural philosophical treatise (composed circa 1603) bears the title Valerius Terminus of the Interpretation of Nature. This study, resting on fresh attention to the surviving authorial manuscript, has three goals. It begins by identifying a lost precursor work apparently entitled "Of Active Knowledge." It then examines the significance of the pseudonyms Bacon chose to introduce his ideas, considering especially his invocation of Erasmus's emblem, the Roman deity Terminus. Finally, it shows how the Valerius Terminus's global vision of contemporary knowledge ultimately helped shape the iconography of Bacon's published Instauratio magna.

  14. The Rule of Three for Prizes in Science and the Bold Triptychs of Francis Bacon.

    Science.gov (United States)

    Goldstein, Joseph L

    2016-09-22

    For many scientific awards, such as Nobels and Laskers, the maximum number of recipients is three. This Rule of Three forces selection committees to make difficult decisions that increase the likelihood of singling out those individuals who open a new field and continue to lead it. The Rule of Three is reminiscent of art's three-panel triptych, a form that the modern master Francis Bacon used to distill complex stories in a bold way. Copyright © 2016 Elsevier Inc. All rights reserved.

  15. Stability of the Spanish version of the five-item Francis Scale of Attitude toward Christianity.

    Science.gov (United States)

    Miranda-Tapia, Giskar Alonso; Cogollo, Zuleima; Herazo, Edwin; Campo-Arias, Adalberto

    2010-12-01

    The aim of this study was to establish test-retest reliability of a Spanish version of the Francis Scale of Attitude toward Christianity (Campo-Arias, Oviedo, & Cogollo, 2009) among adolescent students in Cartagena, Colombia. A group of ninth grade students from two public schools in Colombia (N = 157) completed the five-item scale. Cronbach's alphas were .74 and .76 in the first and second administrations, respectively. Both Pearson's rho and intra-class correlation coefficient were .69. A Spanish translation of the 5-item scale had consistent stability over four weeks.

  16. Influence of the rotor-stator interaction on the dynamic stresses of Francis runners

    International Nuclear Information System (INIS)

    Guillaume, R; Scolaro, D; Deniau, J L; Colombet, C

    2012-01-01

    Thanks to advances in computing capabilities and Computational Fluid Dynamics (CFD) techniques, it is now possible to calculate realistic unsteady pressure fields in Francis turbines. This paper will explain methods to calculate the structural loads and the dynamic behaviour in order to optimize the turbine design and maximize its reliability and lifetime. Depending on the operating conditions of a Francis turbine, different hydraulic phenomena may impact the mechanical behaviour of the structure. According to their nature, these highly variable phenomena should be treated differently and specifically in order to estimate the potential risks arising on submerged structures, in particular the runner. The operating condition studied thereafter is the point at maximum power with the maximum head. Under this condition, the runner is excited by only one dynamic phenomenon named the Rotor-Stator Interaction (RSI). The origin of the phenomenon is located on the radial gap of the turbine and is the source of pressure fluctuations. A fluid-structure analysis is performed to observe the influence of that dynamic pressure field on the runner behaviour. The first part of the paper deals with the unsteady fluid computation. The RSI phenomenon is totally unsteady so the fluid simulation must take into account the entire machine and its rotation movement, in order to obtain a dynamic pressure field. In the second part of the paper, a method suitable for the RSI study is developed. It is known that the fluctuating pressure in this gap can be described as a sum of spatial components. By evaluating these components in the CFD results and on the scale model, it is possible to assess the relevance of the numerical results on the whole runner. After this step, the numerical pressure field can be used as the dynamic load of the structure. The final part of the paper presentsthe mechanical finite element calculations. A modal analysis of the runner in water and a harmonic analysis of its

  17. Sleep and sleep disorders in Don Quixote.

    Science.gov (United States)

    Iranzo, Alex; Santamaria, Joan; de Riquer, Martín

    2004-01-01

    In Don Quijote de la Mancha, Miguel de Cervantes presents Don Quixote as an amazing character of the 17th century who suffers from delusions and illusions, believing himself to be a medieval knight errant. Besides this neuropsychiatric condition, Cervantes included masterful descriptions of several sleep disorders such as insomnia, sleep deprivation, disruptive loud snoring and rapid eye movement sleep behaviour disorder. In addition, he described the occurrence of physiological, vivid dreams and habitual, post-prandial sleepiness--the siesta. Cervantes' concept of sleep as a passive state where all cerebral activities are almost absent is in conflict with his description of abnormal behaviours during sleep and vivid, fantastic dreams. His concept of sleep was shared by his contemporary, Shakespeare, and could have been influenced by the reading of the classical Spanish book of psychiatry Examen de Ingenios (1575).

  18. Francis Bacon's natural history and the Senecan natural histories of early modern Europe.

    Science.gov (United States)

    Jalobeanu, Dana

    2012-01-01

    At various stages in his career, Francis Bacon claimed to have reformed and changed traditional natural history in such a way that his new "natural and experimental history" was unlike any of its ancient or humanist predecessors. Surprisingly, such claims have gone largely unquestioned in Baconian scholarship. Contextual readings of Bacon's natural history have compared it, so far, only with Plinian or humanist natural history. This paper investigates a different form of natural history, very popular among Bacon's contemporaries, but yet unexplored by contemporary students of Bacon's works. I have provisionally called this form of natural history'Senecan' natural history, partly because it took shape in the Neo-Stoic revival of the sixteenth-century, partly because it originates in a particular cosmographical reading of Seneca's Naturales quaestiones. I discuss in this paper two examples of Senecan natural history: the encyclopedic and cosmographical projects of Pierre de la Primaudaye (1546-1619) and Samuel Purchas (1577-1626). I highlight a number of similarities between these two projects and Francis Bacon's natural history, and argue that Senecan natural history forms an important aspect in the historical and philosophical background that needs to be taken into consideration if we want to understand the extent to which Bacon's project to reform natural history can be said to be new.

  19. Prediction of Francis Turbine Prototype Part Load Pressure and Output Power Fluctuations with Hydroelectric Model

    Science.gov (United States)

    Alligné, S.; Nicolet, C.; Béguin, A.; Landry, C.; Gomes, J.; Avellan, F.

    2017-04-01

    The prediction of pressure and output power fluctuations amplitudes on Francis turbine prototype is a challenge for hydro-equipment industry since it is subjected to guarantees to ensure smooth and reliable operation of the hydro units. The European FP7 research project Hyperbole aims to setup a methodology to transpose the pressure fluctuations induced by the cavitation vortex rope from the reduced scale model to the prototype generating units. A Francis turbine unit of 444MW with a specific speed value of ν = 0.29, is considered as case study. A SIMSEN model of the power station including electrical system, controllers, rotating train and hydraulic system with transposed draft tube excitation sources is setup. Based on this model, a frequency analysis of the hydroelectric system is performed for all technologies to analyse potential interactions between hydraulic excitation sources and electrical components. Three technologies have been compared: the classical fixed speed configuration with Synchronous Machine (SM) and the two variable speed technologies which are Doubly Fed Induction Machine (DFIM) and Full Size Frequency Converter (FSFC).

  20. Prediction Method for the Complete Characteristic Curves of a Francis Pump-Turbine

    Directory of Open Access Journals (Sweden)

    Wei Huang

    2018-02-01

    Full Text Available Complete characteristic curves of a pump-turbine are essential for simulating the hydraulic transients and designing pumped storage power plants but are often unavailable in the preliminary design stage. To solve this issue, a prediction method for the complete characteristics of a Francis pump-turbine was proposed. First, based on Euler equations and the velocity triangles at the runners, a mathematical model describing the complete characteristics of a Francis pump-turbine was derived. According to multiple sets of measured complete characteristic curves, explicit expressions for the characteristic parameters of characteristic operating point sets (COPs, as functions of a specific speed and guide vane opening, were then developed to determine the undetermined coefficients in the mathematical model. Ultimately, by combining the mathematical model with the regression analysis of COPs, the complete characteristic curves for an arbitrary specific speed were predicted. Moreover, a case study shows that the predicted characteristic curves are in good agreement with the measured data. The results obtained by 1D numerical simulation of the hydraulic transient process using the predicted characteristics deviate little from the measured characteristics. This method is effective and sufficient for a priori simulations before obtaining the measured characteristics and provides important support for the preliminary design of pumped storage power plants.

  1. Dynamic stresses in a Francis model turbine at deep part load

    Science.gov (United States)

    Weber, Wilhelm; von Locquenghien, Florian; Conrad, Philipp; Koutnik, Jiri

    2017-04-01

    A comparison between numerically obtained dynamic stresses in a Francis model turbine at deep part load with experimental ones is presented. Due to the change in the electrical power mix to more content of new renewable energy sources, Francis turbines are forced to operate at deep part load in order to compensate stochastic nature of wind and solar power and to ensure grid stability. For the extension of the operating range towards deep part load improved understanding of the harsh flow conditions and their impact on material fatigue of hydraulic components is required in order to ensure long life time of the power unit. In this paper pressure loads on a model turbine runner from unsteady two-phase computational fluid dynamics simulation at deep part load are used for calculation of mechanical stresses by finite element analysis. Therewith, stress distribution over time is determined. Since only few runner rotations are simulated due to enormous numerical cost, more effort has to be spent to evaluation procedure in order to obtain objective results. By comparing the numerical results with measured strains accuracy of the whole simulation procedure is verified.

  2. A highly efficient Francis turbine designed for energy recovery in cooling towers

    Directory of Open Access Journals (Sweden)

    Daqing Zhou

    2015-03-01

    Full Text Available In China, cooling water entering cooling towers still retains surplus pressure between 39,240 and 147,150 Pa. In order to utilize this wasted energy, it is suggested that the surplus water energy can be harnessed to drive a type of hydroturbine installed in the inner platform of cooling tower and make the fan rotate via its coupled shafts. However, conventional hydroturbines are not suited for this job because of their low efficiency or unmatched rotating speed with that of the fan under the operating conditions of cooling towers. In this article, according to the requirements of turbine work environment in cooling towers, a new type of hydroturbine, Francis turbine with ultra-low specific speed (ns  = 50 m.kW, was designed to replace the fan motor in a cooling tower. Primarily, the shape, position, and number of runner blades were designed and optimized through theoretical analyses and computational fluid dynamics simulations. Additionally, metal elliptical volute and single-row ring guide vanes were applied to scale down the structural dimensions. Finally, the optimal scheme of the new Francis turbine was proven to have a high efficiency of 88% and good operation stability through testing of a physical model and can achieve the goal of harvesting renewable energy in the cooling tower.

  3. Research on Francis Turbine Modeling for Large Disturbance Hydropower Station Transient Process Simulation

    Directory of Open Access Journals (Sweden)

    Guangtao Zhang

    2015-01-01

    Full Text Available In the field of hydropower station transient process simulation (HSTPS, characteristic graph-based iterative hydroturbine model (CGIHM has been widely used when large disturbance hydroturbine modeling is involved. However, by this model, iteration should be used to calculate speed and pressure, and slow convergence or no convergence problems may be encountered for some reasons like special characteristic graph profile, inappropriate iterative algorithm, or inappropriate interpolation algorithm, and so forth. Also, other conventional large disturbance hydroturbine models are of some disadvantages and difficult to be used widely in HSTPS. Therefore, to obtain an accurate simulation result, a simple method for hydroturbine modeling is proposed. By this method, both the initial operating point and the transfer coefficients of linear hydroturbine model keep changing during simulation. Hence, it can reflect the nonlinearity of the hydroturbine and be used for Francis turbine simulation under large disturbance condition. To validate the proposed method, both large disturbance and small disturbance simulations of a single hydrounit supplying a resistive, isolated load were conducted. It was shown that the simulation result is consistent with that of field test. Consequently, the proposed method is an attractive option for HSTPS involving Francis turbine modeling under large disturbance condition.

  4. Velocity and pressure measurements in guide vane clearance gap of a low specific speed Francis turbine

    Science.gov (United States)

    Thapa, B. S.; Dahlhaug, O. G.; Thapa, B.

    2016-11-01

    In Francis turbine, a small clearance gap between the guide vanes and the cover plates is usually required to pivot guide vanes as a part of governing system. Deflection of cover plates and erosion of mating surfaces causes this gap to increase from its design value. The clearance gap induces the secondary flow in the distributor system. This effects the main flow at the runner inlet, which causes losses in efficiency and instability. A guide vane cascade of a low specific speed Francis turbine has been developed for experimental investigations. The test setup is able to produce similar velocity distributions at the runner inlet as that of a reference prototype turbine. The setup is designed for particle image velocimetry (PIV) measurements from the position of stay vane outlet to the position of runner inlet. In this study, velocity and pressure measurements are conducted with 2 mm clearance gap on one side of guide vane. Leakage flow is observed and measured together with pressure measurements. It is concluded that the leakage flow behaves as a jet and mixes with the main flow in cross-wise direction and forms a vortex filament. This causes non-uniform inlet flow conditions at runner blades.

  5. On the performance of a high head Francis turbine at design and off-design conditions

    International Nuclear Information System (INIS)

    Aakti, B; Amstutz, O; Casartelli, E; Romanelli, G; Mangani, L

    2015-01-01

    In the present paper, fully 360 degrees transient and steady-state simulations of a Francis turbine were performed at three operating conditions, namely at part load (PL), best efficiency point (BEP), and high load (HL), using different numerical approaches for the pressure-velocity coupling. The simulation domain includes the spiral casing with stay and guide vanes, the runner and the draft tube. The main target of the investigations is the numerical prediction of the overall performance of the high head Francis turbine model as well as local and integral quantities of the complete machine in different operating conditions. All results were compared with experimental data published by the workshop organization. All CFD simulations were performed at model scale with a new in-house, 3D, unstructured, object-oriented finite volume code within the framework of the open source OpenFOAM library. The novel fully coupled pressure-based solver is designed to solve the incompressible RANS- Equations and is capable of handling multiple references of frame (MRF). The obtained results show that the overall performance is well captured by the simulations. Regarding the local flow distributions within the inlet section of the draft-tube, the axial velocity is better estimated than the circumferential component

  6. Study on stress characteristics of Francis hydraulic turbine runner based on two-way FSI

    International Nuclear Information System (INIS)

    Zhu, W R; Xiao, R F; Yang, W; Wang, F J; Liu, J

    2012-01-01

    In recent years, cracking phenomenon occurs in many large-sized turbines both nationally and internationally, which has threatened the stable operation of hydraulic turbines. Consequently, Stress characteristics calculation and analysis of a Francis hydraulic turbine runner by application of fluid-structure interaction (FSI) technology become significantly important. In order to introduce two-way coupling technology to hydraulic machinery, two-way FSI technology is applied in this article to calculate and analyze stress characteristics. Through coordinate system transformation, the continuity equations and Navier-Stokes equations in the Cartesian coordinates system are firstly transformed to ALE coordinates system. The fluid field control equations are then constructed and discrete equations can be obtained by using flow-condition-based interpolation (FBIC-C). The structure static mechanics equations used are established in rotation coordinate system, and modeled with the finite method. Two-way coupling is computed by using iteration method. The fluid equations and structure equations are iterated until coupling coefficients converge. According to structure result, the maximum stress, displacement as well as its location can be found. As a result, the most easily wear position can be discovered which provides valuable basis for optimized design and stable operation of Francis hydraulic turbines. After comparing the results with that of one-way coupling, it is discovered that displacements is the key factors which affects the results of one-way and two-way coupling.

  7. On the centenary of the birth of Francis H. C. Crick – from physics to genetics and neuroscience

    Directory of Open Access Journals (Sweden)

    Hélio A. G. Teive

    2016-04-01

    Full Text Available ABSTRACT The year 2016 marks the centenary of the birth of Francis Crick (1916–2004, who made outstanding contributions to genetics and neuroscience. In 1953, in a collaborative study, Francis Crick and James Watson discovered the DNA double helix, and in 1962 they and Maurice Wilkins were awarded the Noble Prize in Physiology or Medicine. Crick subsequently became very interested in neuroscience, particularly consciousness and its relationship to the claustrum, a small gray matter structure between the insula and putamen.

  8. Temporal stability of the Francis Scale of Attitude toward Christianity short-form: test-retest data over one week.

    Science.gov (United States)

    Lewis, Christopher Alan; Cruise, Sharon Mary; McGuckin, Conor

    2005-04-01

    This study evaluated the test-retest reliability of the Francis Scale of Attitude toward Christianity short-form. 39 Northern Irish undergraduate students completed the measure on two occasions separated by one week. Stability across the two administrations was high, r = .92, and there was no significant change between Time 1(M = 25.2, SD = 5.4) and Time 2 (M = 25.7, SD = 6.2). These data support the short-term test-retest reliability of the Francis Scale of Attitude toward Christianity short-form.

  9. Evaluating sources of job satisfaction: A survey of U.S. Fish and Wildlife refuge managers and biologists

    Science.gov (United States)

    Ponds, Phadrea D.; Brinson, Ayeisha A.; Benson, Delwin

    2003-01-01

    The following summary consists of revised excerpts from the thesis study that was conducted in 2000-2002 by Ayeisha Brinson, Colorado State University (Brinson, 2002). The purpose of this report is to provide the U.S. Fish and Wildlife Service (USFWS) with additional finding related to sources of job satisfaction. Because this is a report of additional findings from a length study, the information in this report is condensed and represented without references from the original research. The literature review, methodology, and discussion from the original thesis are not presented in this report. Any questions concerning the thesis should be directed to Ayeisha Brinson, who may be reached by e-mail. The purpose of the report is to examine differences and similarities between National Wildlife Refuge managers and biologists on a selection of independent variable related to job satisfaction occupation status (being either a manager or a biologist): are managers more satisfied with their jobs than biologist? If so, what are the components of that satisfaction? What are the sources of dissatisfaction? a?|

  10. Aesthetic of the subversion and the violence in Francis Bacon and Frida Kahlo’s WorKs of Art

    Directory of Open Access Journals (Sweden)

    Catarina Pinheiro

    2014-06-01

    Full Text Available Having Frida Kahlo and Francis Bacon ́s work as a starting point, the authors discuss the dimensions of violence and trauma present in their creative forms and on the impact produced on the spectator. They also reflect on its connections with the clinic on the impact/countertransference phenomenon and its transformational possibilities.

  11. Internal consistency reliability and construct validity of the Dutch translation of the Francis Scale of Attitude toward Christianity among adolescents.

    Science.gov (United States)

    Francis, L J; Hermans, C A

    2000-02-01

    A sample of 1,021 young people attending Years 7, 8, 9, 10, and 11 at Catholic secondary schools within the state-maintained sector completed the Dutch translation of the Francis Scale of Attitude toward Christianity. The data support its reliability and validity and commend it for further use in studies conducted among young people in The Netherlands.

  12. Aesthetic of the subversion and the violence in Francis Bacon and Frida Kahlo’s WorKs of Art

    OpenAIRE

    Pinheiro, Catarina; Dias, Maria João; Rosa, Alda

    2009-01-01

    Having Frida Kahlo and Francis Bacon ́s work as a starting point, the authors discuss the dimensions of violence and trauma present in their creative forms and on the impact produced on the spectator. They also reflect on its connections with the clinic on the impact/countertransference phenomenon and its transformational possibilities.

  13. Aesthetic of the subversion and the violence in Francis Bacon and Frida Kahlo’s WorKs of Art

    OpenAIRE

    Catarina Pinheiro; Maria João Dias; Alda Rosa

    2014-01-01

    Having Frida Kahlo and Francis Bacon ́s work as a starting point, the authors discuss the dimensions of violence and trauma present in their creative forms and on the impact produced on the spectator. They also reflect on its connections with the clinic on the impact/countertransference phenomenon and its transformational possibilities.

  14. Measuring Attitude toward Theistic Faith: Assessing the Astley-Francis Scale among Christian, Muslim and Secular Youth in England

    Science.gov (United States)

    Francis, Leslie J.; Brockett, Adrian; Village, Andrew

    2013-01-01

    Alongside a family of instruments designed to measure the attitudinal dimension of religion within specific faith contexts (Christianity, Hinduism, Islam, and Judaism), the Astley-Francis Scale of Attitude toward Theistic Faith was designed to assess the attitudinal dimension of religion within a multifaith context. Drawing on a sample of 4338…

  15. Fitness for Kids Who Don't Like Sports

    Science.gov (United States)

    ... Español Fitness for Kids Who Don't Like Sports KidsHealth / For Parents / Fitness for Kids Who Don' ... look for something new. Still Shopping for a Sport Some kids haven't found the right sport. ...

  16. Reading "Las Meninas": An Ekphrastic Approach to Teaching "Don Quijote"

    Science.gov (United States)

    Ortuno, Marian

    2012-01-01

    Reading and teaching "Don Quijote" present multiple challenges to twenty-first century students and instructors who are culturally and historically distanced from the seventeenth century. With "Las Meninas" serving as a visual lexicon for cuing correlative themes and events in "Don Quijote", the instructor, through an ekphrastic, interdisciplinary…

  17. Fungal flora and deoxynivalenol (DON) level in wheat from Jeddah ...

    African Journals Online (AJOL)

    This study aimed to explore the fungal flora along with the DON concentration in the collected wheat samples from Jeddah market to correlate between this flora and the detected DON. Whole grain wheat samples were collected from Jeddah market and this represents imported and locally produced wheat. The results ...

  18. Don Quixote og romangenren

    DEFF Research Database (Denmark)

    Kluge, Sofie

    Through the centuries Cervantes' Don Quixote (1605/1615) has delighted readers, inspired artists, and helped form our perception of early modern Spain. Moreover, it has played a major part in the development and theoretisation of one of the modern world's most central artistic forms: the novel. Don...

  19. Francis Bacon's concept of objectivity and the idols of the mind.

    Science.gov (United States)

    Zagorin, P

    2001-12-01

    This paper examines the concept of objectivity traceable in Francis Bacon's natural philosophy. After some historical background on this concept, it considers the question of whether it is not an anachronism to attribute such a concept to Bacon, since the word 'objectivity' is a later coinage and does not appear anywhere in his writings. The essay gives reasons for answering this question in the negative, and then criticizes the accounts given of Bacon's understanding of objectivity by Lorraine Daston and Julie Robin Solomon. It argues that this understanding is most directly and fully expressed in his discussion of the idols of the mind. In this connection, the paper notes Bacon's critical attitude to sixteenth-century scepticism and its relevance to the idea of objectivity implicit in his comments on the idols. In conclusion, the paper argues that Bacon was not a pure empiricist and describes the place assigned to theories and hypotheses in his natural philosophy.

  20. Images of trauma: pain, recognition, and disavowal in the works of Frida Kahlo and Francis Bacon.

    Science.gov (United States)

    Bose, Joerg

    2005-01-01

    The role of art in the encounter with trauma and destructiveness is comparatively studied in the works of Frida Kahlo and Francis Bacon as examples of a direct and a more indirect way of dealing with such experiences. A creative product may function intrapsychically as a kind of messenger between dissociated self-states and consciousness, and it may also serve as a witnessing presence in a self-supporting and self-constituting way. Artistic work may thus be used by the artist for an expressive as well as for a protective purpose, as a means of sympathetic participation in painful experience, or as a medium for a view from the outside. The act itself of finding and of making expressive forms at the time of traumatic experience is a remarkable assertion of the human capability to synthesize and to counteract fragmenting dissociative processes.

  1. Special article: Francis Hoeffer McMechan, MD: creator of modern anesthesiology?

    Science.gov (United States)

    Bacon, Douglas R

    2012-12-01

    If one person can be credited with the creation of the infrastructure of modern anesthesiology, that individual would be Francis Hoeffer McMechan. He has been largely forgotten since his death in 1939 despite his remarkable and enduring accomplishments. McMechan edited the first national journal devoted to anesthesiology, created and managed almost all of the national and regional societies devoted to the specialty between 1912 and his death, and created the first international physician certification as a specialist in anesthesiology. His accomplishments are even more amazing given the severe arthritis that left him wheelchair-bound for almost his entire professional life and denied him the ability to practice anesthesia. Our specialty owes an incredible debt to this largely unknown and unsung hero.

  2. Scanning-PIXE analysis of gold lace embroideries in a relic of St. Francis

    Energy Technology Data Exchange (ETDEWEB)

    Migliori, A. [Dipartimento di Fisica dell' Universita and Istituto Nazionale di Fisica Nucleare, Firenze, Via G. Sansone 1, 50019 Sesto Fiorentino (Firenze) (Italy)], E-mail: migliori@fi.infn.it; Grassi, N.; Mando, P.A. [Dipartimento di Fisica dell' Universita and Istituto Nazionale di Fisica Nucleare, Firenze, Via G. Sansone 1, 50019 Sesto Fiorentino (Firenze) (Italy)

    2008-05-15

    In this work, we describe the compositional analysis performed by scanning-mode PIXE on the metal threads of a XIII century embroidery. The precious work analysed is the pillow-case used to cover the pillow, on which - according to tradition - St. Francis of Assisi was resting his head when he died. Measurements were performed in order to characterise the embroideries of the two sides and the passementerie in the lateral hems. Several areas, each of the order of two square millimetres, were scanned with a 3 MeV proton external beam of 20 {mu}m size on target, using the external micro-beam facility of our laboratory, with list-mode acquisition. Analysis of elemental maps and spectra from selected homogeneous sub-areas allowed us to extract the quantitative composition of the gilded tape and estimates of its thickness.

  3. Scanning-PIXE analysis of gold lace embroideries in a relic of St. Francis

    International Nuclear Information System (INIS)

    Migliori, A.; Grassi, N.; Mando, P.A.

    2008-01-01

    In this work, we describe the compositional analysis performed by scanning-mode PIXE on the metal threads of a XIII century embroidery. The precious work analysed is the pillow-case used to cover the pillow, on which - according to tradition - St. Francis of Assisi was resting his head when he died. Measurements were performed in order to characterise the embroideries of the two sides and the passementerie in the lateral hems. Several areas, each of the order of two square millimetres, were scanned with a 3 MeV proton external beam of 20 μm size on target, using the external micro-beam facility of our laboratory, with list-mode acquisition. Analysis of elemental maps and spectra from selected homogeneous sub-areas allowed us to extract the quantitative composition of the gilded tape and estimates of its thickness

  4. Scanning-PIXE analysis of gold lace embroideries in a relic of St. Francis

    Science.gov (United States)

    Migliori, A.; Grassi, N.; Mandò, P. A.

    2008-05-01

    In this work, we describe the compositional analysis performed by scanning-mode PIXE on the metal threads of a XIII century embroidery. The precious work analysed is the pillow-case used to cover the pillow, on which - according to tradition - St. Francis of Assisi was resting his head when he died. Measurements were performed in order to characterise the embroideries of the two sides and the passementerie in the lateral hems. Several areas, each of the order of two square millimetres, were scanned with a 3 MeV proton external beam of 20 μm size on target, using the external micro-beam facility of our laboratory, with list-mode acquisition. Analysis of elemental maps and spectra from selected homogeneous sub-areas allowed us to extract the quantitative composition of the gilded tape and estimates of its thickness.

  5. Adam Smith e Francis Ysidro Edgeworth: uma crítica do utilitarismo

    Directory of Open Access Journals (Sweden)

    Solange Regina Marin

    2012-01-01

    Full Text Available Sugerimos, nesse trabalho, a investigação das concepções de Adam Smith e a de Francis Ysidro Edgeworth do utilitarismo. Ambas as concepções foram utilizadas para desenvolver a Ciência Econômica. Porém, também apresentaram as limitações da teoria econômica, cujas fronteiras vislumbradas pelos autores remetem para a necessidade de avaliar as ações e condutas humanas com teoria moral diferente do utilitarismo. Entendemos que a teoria moral de Adam Smith, esquecida pela história do pensamento econômico, se apresenta como alternativa e, em decorrência, uma ideia promissora para aperfeiçoar o estudo das ações e condutas ditas econômicas.

  6. Unsteady hydraulic simulation of the cavitating part load vortex rope in Francis turbines

    Science.gov (United States)

    Brammer, J.; Segoufin, C.; Duparchy, F.; Lowys, P. Y.; Favrel, A.; Avellan, F.

    2017-04-01

    For Francis turbines at part load operation a helical vortex rope is formed due to the swirling nature of the flow exiting the runner. This vortex creates pressure fluctuations which can lead to power swings, and the unsteady loading can lead to fatigue damage of the runner. In the case that the vortex rope cavitates there is the additional risk that hydro-acoustic resonance can occur. It is therefore important to be able to accurately simulate this phenomenon to address these issues. In this paper an unsteady, multi-phase CFD model was used to simulate two part-load operating points, for two different cavitation conditions. The simulation results were validated with test-rig data, and showed very good agreement. These results also served as an input for FEA calculations and fatigue analysis, which are presented in a separate study.

  7. Classics in psychiatry and the law: Francis Wharton on involuntary confessions.

    Science.gov (United States)

    Weiss, Kenneth J

    2012-01-01

    Philadelphia attorney Francis Wharton was a key intellectual figure in linking the sciences of medicine and law. In 1860, he published a monograph on involuntary confessions, which represented the closing chapter of Wharton and Stillé's Treatise on Medical Jurisprudence. He had already published A Monograph on Mental Unsoundness in 1855, the first book of the Treatise in its first edition. Wharton was convinced that many criminals had an inner compulsion to confess or to be caught, explained as divine jurisprudence. His remarks on confessions include a typology spanning psychodynamics to police tactics, using contemporaneous, historical, and literary examples. This remarkable document provides insight into the dynamics of unintended and involuntary confessions and is compatible, in part, with current scholarship. The author contrasts Wharton's schema with those of his English predecessor Jeremy Bentham, the psychoanalyst Theodore Reik, and others, and concludes that it represents an important transition toward a psychological approach to the criminology of confessions.

  8. Modelling and Internal Fuzzy Model Power Control of a Francis Water Turbine

    Directory of Open Access Journals (Sweden)

    Klemen Nagode

    2014-02-01

    Full Text Available This paper presents dynamic modelling of a Francis turbine with a surge tank and the control of a hydro power plant (HPP. Non-linear and linear models include technical parameters and show high similarity to measurement data. Turbine power control with an internal model control (IMC is proposed, based on a turbine fuzzy model. Considering appropriate control responses in the entire area of turbine power, the model parameters of the process are determined from a fuzzy model, which are further included in the internal model controller. The results are compared to a proportional-integral (PI controller tuned with an integral absolute error (IAE objective function, and show an improved response of internal model control.

  9. A world in one dimension: Linus Pauling, Francis Crick and the central dogma of molecular biology.

    Science.gov (United States)

    Strasser, Bruno J

    2006-01-01

    In 1957, Francis Crick outlined a startling vision of life in which the great diversity of forms and shapes of macromolecules was encoded in the one-dimensional sequence of nucleic acids. This paper situates Crick's new vision in the debates of the 1950s about protein synthesis and gene action. After exploring the reception of Crick's ideas, it shows how they differed radically from a different model of protein synthesis which enjoyed wide currency in that decade. In this alternative model, advocated by Linus Pauling and other luminaries, three-dimensional templates directed the folding of proteins. Even though it was always considered somewhat speculative, this theory was supported by a number of empirical results originating in different experimental systems. It was eventually replaced by a model in which the forms and shapes of macromolecules resulted solely from their amino acid sequence, dramatically simplifying the problem of protein synthesis which Crick was attempting to solve in 1957.

  10. Numerical investigation of flow structure and pressure pulsation in the Francis-99 turbine during startup

    Science.gov (United States)

    Minakov, A.; Sentyabov, A.; Platonov, D.

    2017-01-01

    We performed numerical simulation of flow in a laboratory model of a Francis hydroturbine at startup regimes. Numerical technique for calculating of low frequency pressure pulsations in a water turbine is based on the use of DES (k-ω Shear Stress Transport) turbulence model and the approach of “frozen rotor”. The structure of the flow behind the runner of turbine was analysed. Shows the effect of flow structure on the frequency and intensity of non-stationary processes in the flow path. Two version of the inlet boundary conditions were considered. The first one corresponded measured time dependence of the discharge. Comparison of the calculation results with the experimental data shows the considerable delay of the discharge in this calculation. Second version corresponded linear approximation of time dependence of the discharge. This calculation shows good agreement with experimental results.

  11. The Southern Society for Philosophy and Psychology and Francis Cecil Sumner.

    Science.gov (United States)

    Thomas, Roger K

    2011-01-01

    In 1939, a psychologist could become a member of the Southern Society for Philosophy and Psychology (SSPP) automatically with the endorsement of two members, payment of dues, and membership in the American Psychological Association (APA). Non-APA members with endorsements and payment of dues had to be voted in by the membership. In 1940, the rules for admission were changed to eliminate the automatic membership for APA members. Francis Cecil Sumner, the first African American PhD in psychology, qualified for SSPP membership as a member of the APA in 1939, but the SSPP's council delayed his membership and introduced the amendment to its constitution that eliminated Sumner's route to membership. This article examines the circumstances surrounding council's actions and the role that Sumner's application for membership played in it as an example of the role that race and discrimination played in the decision to change the route to SSPP membership for members of the APA.

  12. The Welcoming Pope: Images of Pope Francis in the Catholicism under mediatization

    Directory of Open Access Journals (Sweden)

    Tatiane MILANI

    2017-12-01

    Full Text Available In the context of the society in mediatization more and more the social fields are inserted in an ambiance in which borders are constantly tensioned, meaning that social practices are crossed by the logic of other fields, rather than their own place of knowing. It is perceived that the social/political/religious conjuncture interpenetrates with the logic of mediatization, and this phenomenon arouses transformations in all Christianity. The objective of this work is to analyze the circulation of Pope Francis' images in the media which formulate, in the collective imaginary, a mediated totem image of the Pope of embrace or of the welcoming Pope, what adheres to the new media technologies.

  13. On the upper part load vortex rope in Francis turbine: Experimental investigation

    International Nuclear Information System (INIS)

    Nicolet, C; Zobeiri, A; Maruzewski, P; Avellan, F

    2010-01-01

    The swirling flow developing in Francis turbine draft tube under part load operation leads to pressure fluctuations usually in the range of 0.2 to 0.4 times the runner rotational frequency resulting from the so-called vortex breakdown. For low cavitation number, the flow features a cavitation vortex rope animated with precession motion. Under given conditions, these pressure fluctuations may lead to undesirable pressure fluctuations in the entire hydraulic system and also produce active power oscillations. For the upper part load range, between 0.7 and 0.85 times the best efficiency discharge, pressure fluctuations may appear in a higher frequency range of 2 to 4 times the runner rotational speed and feature modulations with vortex rope precession. It has been pointed out that for this particular operating point, the vortex rope features elliptical cross section and is animated of a self-rotation. This paper presents an experimental investigation focusing on this peculiar phenomenon, defined as the upper part load vortex rope. The experimental investigation is carried out on a high specific speed Francis turbine scale model installed on a test rig of the EPFL Laboratory for Hydraulic Machines. The selected operating point corresponds to a discharge of 0.83 times the best efficiency discharge. Observations of the cavitation vortex carried out with high speed camera have been recorded and synchronized with pressure fluctuations measurements at the draft tube cone. First, the vortex rope self rotation frequency is evidenced and the related frequency is deduced. Then, the influence of the sigma cavitation number on vortex rope shape and pressure fluctuations is presented. The waterfall diagram of the pressure fluctuations evidences resonance effects with the hydraulic circuit. The time evolution of the vortex rope volume is compared with pressure fluctuations time evolution using image processing. Finally, the influence of the Froude number on the vortex rope shape and

  14. On the upper part load vortex rope in Francis turbine: Experimental investigation

    Energy Technology Data Exchange (ETDEWEB)

    Nicolet, C [Power Vision Engineering sarl Ch. des Champs-Courbes 1, CH-1024 Ecublens (Switzerland); Zobeiri, A; Maruzewski, P; Avellan, F, E-mail: christophe.nicolet@powervision-eng.c [Laboratory for Hydraulic Machines, Ecole polytechnique federale de Lausanne, EPFL Av. de Cour 33bis, CH-1007 Lausanne (Switzerland)

    2010-08-15

    The swirling flow developing in Francis turbine draft tube under part load operation leads to pressure fluctuations usually in the range of 0.2 to 0.4 times the runner rotational frequency resulting from the so-called vortex breakdown. For low cavitation number, the flow features a cavitation vortex rope animated with precession motion. Under given conditions, these pressure fluctuations may lead to undesirable pressure fluctuations in the entire hydraulic system and also produce active power oscillations. For the upper part load range, between 0.7 and 0.85 times the best efficiency discharge, pressure fluctuations may appear in a higher frequency range of 2 to 4 times the runner rotational speed and feature modulations with vortex rope precession. It has been pointed out that for this particular operating point, the vortex rope features elliptical cross section and is animated of a self-rotation. This paper presents an experimental investigation focusing on this peculiar phenomenon, defined as the upper part load vortex rope. The experimental investigation is carried out on a high specific speed Francis turbine scale model installed on a test rig of the EPFL Laboratory for Hydraulic Machines. The selected operating point corresponds to a discharge of 0.83 times the best efficiency discharge. Observations of the cavitation vortex carried out with high speed camera have been recorded and synchronized with pressure fluctuations measurements at the draft tube cone. First, the vortex rope self rotation frequency is evidenced and the related frequency is deduced. Then, the influence of the sigma cavitation number on vortex rope shape and pressure fluctuations is presented. The waterfall diagram of the pressure fluctuations evidences resonance effects with the hydraulic circuit. The time evolution of the vortex rope volume is compared with pressure fluctuations time evolution using image processing. Finally, the influence of the Froude number on the vortex rope shape and

  15. On the upper part load vortex rope in Francis turbine: Experimental investigation

    Science.gov (United States)

    Nicolet, C.; Zobeiri, A.; Maruzewski, P.; Avellan, F.

    2010-08-01

    The swirling flow developing in Francis turbine draft tube under part load operation leads to pressure fluctuations usually in the range of 0.2 to 0.4 times the runner rotational frequency resulting from the so-called vortex breakdown. For low cavitation number, the flow features a cavitation vortex rope animated with precession motion. Under given conditions, these pressure fluctuations may lead to undesirable pressure fluctuations in the entire hydraulic system and also produce active power oscillations. For the upper part load range, between 0.7 and 0.85 times the best efficiency discharge, pressure fluctuations may appear in a higher frequency range of 2 to 4 times the runner rotational speed and feature modulations with vortex rope precession. It has been pointed out that for this particular operating point, the vortex rope features elliptical cross section and is animated of a self-rotation. This paper presents an experimental investigation focusing on this peculiar phenomenon, defined as the upper part load vortex rope. The experimental investigation is carried out on a high specific speed Francis turbine scale model installed on a test rig of the EPFL Laboratory for Hydraulic Machines. The selected operating point corresponds to a discharge of 0.83 times the best efficiency discharge. Observations of the cavitation vortex carried out with high speed camera have been recorded and synchronized with pressure fluctuations measurements at the draft tube cone. First, the vortex rope self rotation frequency is evidenced and the related frequency is deduced. Then, the influence of the sigma cavitation number on vortex rope shape and pressure fluctuations is presented. The waterfall diagram of the pressure fluctuations evidences resonance effects with the hydraulic circuit. The time evolution of the vortex rope volume is compared with pressure fluctuations time evolution using image processing. Finally, the influence of the Froude number on the vortex rope shape and

  16. Prediction of a Francis turbine prototype full load instability from investigations on the reduced scale model

    Science.gov (United States)

    Alligné, S.; Maruzewski, P.; Dinh, T.; Wang, B.; Fedorov, A.; Iosfin, J.; Avellan, F.

    2010-08-01

    The growing development of renewable energies combined with the process of privatization, lead to a change of economical energy market strategies. Instantaneous pricings of electricity as a function of demand or predictions, induces profitable peak productions which are mainly covered by hydroelectric power plants. Therefore, operators harness more hydroelectric facilities at full load operating conditions. However, the Francis Turbine features an axi-symmetric rope leaving the runner which may act under certain conditions as an internal energy source leading to instability. Undesired power and pressure fluctuations are induced which may limit the maximum available power output. BC Hydro experiences such constraints in a hydroelectric power plant consisting of four 435 MW Francis Turbine generating units, which is located in Canada's province of British Columbia. Under specific full load operating conditions, one unit experiences power and pressure fluctuations at 0.46 Hz. The aim of the paper is to present a methodology allowing prediction of this prototype's instability frequency from investigations on the reduced scale model. A new hydro acoustic vortex rope model has been developed in SIMSEN software, taking into account the energy dissipation due to the thermodynamic exchange between the gas and the surrounding liquid. A combination of measurements, CFD simulations and computation of eigenmodes of the reduced scale model installed on test rig, allows the accurate calibration of the vortex rope model parameters at the model scale. Then, transposition of parameters to the prototype according to similitude laws is applied and stability analysis of the power plant is performed. The eigenfrequency of 0.39 Hz related to the first eigenmode of the power plant is determined to be unstable. Predicted frequency of the full load power and pressure fluctuations at the unit unstable operating point is found to be in general agreement with the prototype measurements.

  17. Prediction of a Francis turbine prototype full load instability from investigations on the reduced scale model

    International Nuclear Information System (INIS)

    Alligne, S; Maruzewski, P; Avellan, F; Dinh, T; Wang, B; Fedorov, A; Iosfin, J

    2010-01-01

    The growing development of renewable energies combined with the process of privatization, lead to a change of economical energy market strategies. Instantaneous pricings of electricity as a function of demand or predictions, induces profitable peak productions which are mainly covered by hydroelectric power plants. Therefore, operators harness more hydroelectric facilities at full load operating conditions. However, the Francis Turbine features an axi-symmetric rope leaving the runner which may act under certain conditions as an internal energy source leading to instability. Undesired power and pressure fluctuations are induced which may limit the maximum available power output. BC Hydro experiences such constraints in a hydroelectric power plant consisting of four 435 MW Francis Turbine generating units, which is located in Canada's province of British Columbia. Under specific full load operating conditions, one unit experiences power and pressure fluctuations at 0.46 Hz. The aim of the paper is to present a methodology allowing prediction of this prototype's instability frequency from investigations on the reduced scale model. A new hydro acoustic vortex rope model has been developed in SIMSEN software, taking into account the energy dissipation due to the thermodynamic exchange between the gas and the surrounding liquid. A combination of measurements, CFD simulations and computation of eigenmodes of the reduced scale model installed on test rig, allows the accurate calibration of the vortex rope model parameters at the model scale. Then, transposition of parameters to the prototype according to similitude laws is applied and stability analysis of the power plant is performed. The eigenfrequency of 0.39 Hz related to the first eigenmode of the power plant is determined to be unstable. Predicted frequency of the full load power and pressure fluctuations at the unit unstable operating point is found to be in general agreement with the prototype measurements.

  18. DAYA ANTIBAKTERI EKSTRAK ETANOL DAUN SENGGANI (Melastoma affine D. Don

    Directory of Open Access Journals (Sweden)

    Ika Trisharyanti Dian Kusumowati

    2014-08-01

    Full Text Available Melastoma affine D. Don had some activities such as anthelmintic, antibacteria, antiinfiammation, antifungal, and antitumor. The aims of this research was determine antibacteria activity of ethanolic extract of Melastoma affine D. Don. The antimicrobial activity was tested by solid dilution method to get Minimum Inhibition Concentration (MIC. The compounds in Melastoma affine D. Don was analyzed by tube test method and Thin Layer Chromatography (TLC with chloroform : methanol : formic acid (8,5:1,5:0,5 as mobile phase and silica gel GF254 as stationary phase. The result showed ethanolic extract of Melastoma affine D. Don contains alkaloid, polyphenol, fiavonoid, saponin, and essential oil. The MIC of Senggani against Staphylococcus aureus was 2% and 3% against Escherichia coli and the extract could not inhibit Staphylococcus aureus and Escherichia coli multiresistant until concentration 7% extract ethanol. Keywords: Melastoma affine D. Don, Staphylococcus aureus, Escherichia coli

  19. Don't be such a scientist talking substance in an age of style

    CERN Document Server

    Olson, Randy

    2009-01-01

    How to relate scientific information in a way that entertains and enlightens? After twenty years as a marine biologist, a Ph.D. from Harvard, a tenured professorship at the University of New Hampshire, and more than twenty published research papers, why is Dr. Randy Olson telling readers, 'Don't Be Such a Scientist'? The hard-earned advice comes from a fifteen-year career transition to filmmaking, culminating in the acclaimed documentaries "Flock of Dodos: The Evolution-Intelligent Design Circus" and "Sizzle: A Global Warming Comedy". In his first book, Olson makes clear what those glued to their microscopes and climate models may not recognize: the general public doesn't speak science. For better or worse, most of us rely not on intellect, but on what Olson terms the organs of mass communication: the heart, the gut, and even 'the lower organs'. Why else do some still question the existence of global warming or evolution when the evidence is irrefutable? Drawing on his own hilarious - and at times humiliating...

  20. "Early Psychosis" as a mirror of biologist controversies in post-war German, Anglo-Saxon, and Soviet Psychiatry.

    Science.gov (United States)

    Rzesnitzek, Lara

    2013-01-01

    The English term "early psychosis" was coined in the 1930s to refer to feelings of irritability, loss of concentration, hypochondriac ideas, moodiness, and lassitude that were seen to precede the onset of clear-cut hallucinations and delusions. The history of thinking about "early psychosis" under names such as "latent," "masked," "mild," "simple" or "sluggish" schizophrenia before World War II and afterwards on the different sides of the Wall and the Iron Curtain reveals "early psychosis" as a mirror of quite aged international biologist controversies that are still alive today and to the same extent as they are misunderstood, are influential in their implications in today's psychiatry.

  1. Quantum Physics for Scientists and Technologists Fundamental Principles and Applications for Biologists, Chemists, Computer Scientists, and Nanotechnologists

    CERN Document Server

    Sanghera, Paul

    2011-01-01

    Presenting quantum physics for the non-physicists, Quantum Physics for Scientists and Technologists is a self-contained, cohesive, concise, yet comprehensive, story of quantum physics from the fields of science and technology, including computer science, biology, chemistry, and nanotechnology. The authors explain the concepts and phenomena in a practical fashion with only a minimum amount of math. Examples from, and references to, computer science, biology, chemistry, and nanotechnology throughout the book make the material accessible to biologists, chemists, computer scientists, and non-techn

  2. Bioavailability of dissolved organic nitrogen (DON) in wastewaters from animal feedlots and storage lagoons

    Science.gov (United States)

    Dissolved organic nitrogen (DON) transport from animal agriculture to surface waters can lead to eutrophication and dissolved oxygen depletion. Biodegradable DON (BDON) is a portion of DON that is mineralized by bacteria while bioavailable DON (ABDON) is utilized by bacteria and/or algae. This stu...

  3. The President's pleasant surprise: how LGBT advocates ended Don't Ask, Don't Tell.

    Science.gov (United States)

    Frank, Nathaniel

    2013-01-01

    This study assesses the role of LGBT advocates in repealing the military's Don't Ask, Don't Tell policy in the U.S. Congress. It draws on the author's direct involvement with that effort as well as personal interviews and media evidence to consider the contributions of the Obama Administration, members of Congress, the media, and individuals and pressure groups in the repeal process. It argues that repeal succeeded not because of the effective implementation of a White House plan but because the pressure of LGBT advocates ultimately shattered several key obstacles including inadequate messaging and dysfunction and inertia among both politicians and interest groups in Washington. The article offers insight into the role of public pressure in forwarding social change.

  4. DON-induced changes in bone homeostasis in mink dams

    Directory of Open Access Journals (Sweden)

    Tomaszewska Ewa

    2017-09-01

    Full Text Available Introduction: The aim of the study was to investigate the mechanical and geometric properties as well as bone tissue and mineral density of long bones in mink dams exposed to deoxynivalenol (DON since one day after mating, throughout gestation (ca. 46 d and lactation to pelt harvesting. Material and Methods: Thirty clinically healthy multiparous minks (Neovison vison of the standard dark brown type were used. After the mating, the minks were randomly assigned into two equal groups: nontreated control group and DON group fed wheat contaminated naturally with DON at a concentration of 1.1 mg·kg-1 of feed. Results: The final body weight and weight and length of the femur did not differ between the groups. However, DON contamination decreased mechanical endurance of the femur. Furthermore, DON reduced the mean relative wall thickness and vertical wall thickness of the femur, while vertical cortical index, midshaft volume, and cross-sectional moment of inertia increased. Finally, DON contamination did not alter bone tissue density, bone mineral density, or bone mineral content, but decreased the values of all investigated structural and material properties. Conclusion: DON at applied concentration probably intensified the process of endosteal resorption, which was the main reason for bone wall thinning and the weakening of the whole bone.

  5. Goober: A fully integrated and user-friendly microarray data management and analysis solution for core labs and bench biologists

    Directory of Open Access Journals (Sweden)

    Luo Wen

    2009-03-01

    Full Text Available Despite the large number of software tools developed to address different areas of microarray data analysis, very few offer an all-in-one solution with little learning curve. For microarray core labs, there are even fewer software packages available to help with their routine but critical tasks, such as data quality control (QC and inventory management. We have developed a simple-to-use web portal to allow bench biologists to analyze and query complicated microarray data and related biological pathways without prior training. Both experiment-based and gene-based analysis can be easily performed, even for the first-time user, through the intuitive multi-layer design and interactive graphic links. While being friendly to inexperienced users, most parameters in Goober can be easily adjusted via drop-down menus to allow advanced users to tailor their needs and perform more complicated analysis. Moreover, we have integrated graphic pathway analysis into the website to help users examine microarray data within the relevant biological content. Goober also contains features that cover most of the common tasks in microarray core labs, such as real time array QC, data loading, array usage and inventory tracking. Overall, Goober is a complete microarray solution to help biologists instantly discover valuable information from a microarray experiment and enhance the quality and productivity of microarray core labs. The whole package is freely available at http://sourceforge.net/projects/goober. A demo web server is available at http://www.goober-array.org.

  6. Don Joaquin García Monge

    Directory of Open Access Journals (Sweden)

    Agustín Rodríguez Garavito

    1958-11-01

    Full Text Available Los conocimos personalmente y tratamos de cerca en su amada ciudad de San José de Costa Rica. Casi diariamente íbamos por su casa. Una mansión grande, de vastos y sonoros corredores, arcones antiguos, libros apilados por doquier. Don Joaquín mantenía el timón de El Repertorio Americano, una de las más nobles publicaciones intelectuales del Continente. Dialogábamos con él sobre temas de mucha entidad, mientras la noche caía lentamente sobre este dulce país de porcelana tan grato a las veladas antiguas, aquellas donde se puede oír el latido del corazón como en el poema chino.

  7. Don quijote, Christelike geloof en natuurwetenskap 1

    Directory of Open Access Journals (Sweden)

    H. P.P. Lötter

    1987-03-01

    Full Text Available The story about Don Qulchote and the windmills is used in this article as an analogy to typify the debates that have taken place in history between natural science and representatives of Christian religion. The analogy is tested on debates that took place around Galileo. Darwin, Newton, Cuvier and the Big Bang theory. The analogy matches these debates quite well and this Is explained by the view that scientific claims to knowledge, and claims to knowledge based on Christian faith, belong to different categories and are thus not concurrents for the same truth. Gilbert Ryle's criticism on Descartes' mind-body dualism is used here to strengthen this argument. The article is concluded by pointing out in what ways one can engage in a meaningful debate on the nature of the relationship between science and Christian religion.

  8. Sir Francis Joseph Campbell and His Family: The First Family in Professional Services for People Who Are Blind or Visually Impaired

    Science.gov (United States)

    Welsh, Richard L.

    2008-01-01

    The author discusses the pivotal roles of Sir Francis Campbell (1832-1914) and members of his family, especially his son Charles Campbell, in the evolution of the blindness field to a professional and reason-based service.

  9. We don't need another hero.

    Science.gov (United States)

    Badaracco, J L

    2001-09-01

    Everybody loves the stories of heroes like Martin Luther King, Jr., Mother Teresa, and Gandhi. But the heroic model of moral leadership usually doesn't work in the corporate world. Modesty and restraint are largely responsible for the achievements of the most effective moral leaders in business. The author, a specialist in business ethics, says the quiet leaders he has studied follow four basic rules in meeting ethical challenges and making decisions. The rules constitute an important resource for executives who want to encourage the development of such leaders among their middle managers. The first rule is "Put things off till tomorrow." The passage of time allows turbulent waters to calm and lets leaders' moral instincts emerge. "Pick your battles" means that quiet leaders don't waste political capital on fights they can't win; they save it for occasions when they really want to fight. "Bend the rules, don't break them" sounds easier than it is--bending the rules in order to resolve a complicated situation requires imagination, discipline, restraint, flexibility, and entrepreneurship. The fourth rule, "Find a compromise," reflects the author's finding that quiet leaders try not to see situations as polarized tests of ethical principles. These individuals work hard to craft compromises that are "good enough"--responsible and workable enough--to satisfy themselves, their companies, and their customers. The vast majority of difficult problems are solved through the consistent striving of people working far from the limelight. Their quiet approach to leadership doesn't inspire, thrill, or provide story lines for uplifting TV shows. But the unglamorous efforts of quiet leaders make a tremendous difference every day in the corporate world.

  10. On the physical mechanisms governing self-excited pressure surge in Francis turbines

    International Nuclear Information System (INIS)

    Müller, A; Favrel, A; Landry, C; Yamamoto, K; Avellan, F

    2014-01-01

    The required operating range for hydraulic machines is continually extended in an effort to integrate renewable energy sources with unsteady power outputs into the existing electrical grid. The off-design operation however brings forth unfavorable flow patterns in the machine, causing dynamic problems involving cavitation, which may represent a limiting factor to the energy production. In Francis turbines it is observed that the self-excited oscillation of a vortex rope in the draft tube cone prevents the delivery of maximum power when required. This phenomenon is referred to as full load pressure surge and has been the object of extensive research during the past decades. Several contributions deepened its understanding through measurement and simulation of the local flow properties and the global stability parameters. The draft tube pressure level and the runner outlet swirl are identified as key variables in the modelling of the vortex rope dynamics. Recently, a cyclic appearance of blade cavitation has been observed at overload conditions in a multiphase numerical simulation coupling the runner and the draft tube. From the analysis of the simulation it becomes obvious that the cyclic appearance of blade cavitation has a direct effect on the runner outlet swirl, thus introducing an additional interaction mechanism that is not accounted for in formerly published models. For the presented work, the results of this numerical study are confirmed experimentally on a reduced scale model of a Francis turbine. Several wall pressure measurements in the draft tube cone are performed, together with high speed visualizations of the vortex rope and the blade cavitation. The flow swirl is calculated based on Laser Doppler Velocimetry measurements. A possible mechanism explaining the coupling between the self-excited pressure and vortex rope oscillation and the cyclic appearance of the blade cavitation is proposed. Furthermore, the streamwise propagation speed of the flow

  11. On the sloshing free surface in the draft tube cone of a Francis turbine operating in synchronous condenser mode

    Science.gov (United States)

    Vagnoni, E.; Andolfatto, L.; Avellan, F.

    2017-04-01

    Hydropower plants may be required to operate in synchronous condenser mode in order to supply reactive power to the grid for compensating the fluctuations introduced by the intermittent renewable energies such wind and solar. When operating in this mode, the tail water in the Francis turbine or pump-turbine is depressed below the runner by injecting pressurized air in order to spin in air to reduce the power consumption. Many air-water interaction phenomena occur in the machine causing air losses and a consequent power consumption to recover the air lost. In this paper, the experimental investigation of the sloshing motion in the cone of a dewatered Francis turbine performed by image visualization and pressure measurements is presented. The developed image post processing method for identifying the amplitude and frequency of the oscillation of the free surface is described and the results obtained are illustrated and discussed.

  12. Fukuyama : kõigepealt hea valitsus, siis demokraatia ja ajaloo lõpp / Francis Fukuyama ; interv. Nathan Gardels

    Index Scriptorium Estoniae

    Fukuyama, Francis

    2005-01-01

    Francis Fukuyama sõnul vajab riik oma arenguks esmajoones head valitsemist. Kõige olulisem on, et oleks toimiv riik, mis suudab tagada julgeoleku ja majandusarengu elementaarsed tingimused. Iraagi praeguste probleemide põhjus on selles, et USA ei suutnud ette näha, kuidas riik Saddami kukkudes kokku variseb, kuid tuleb mõista, et aeg-ajalt on USA ja kogu maailma huvides kusagil maailma nurgas riigi ehitamine tõsiselt ette võtta, ütleb autor

  13. Numerical analysis of solid–liquidtwo-phase turbulent flow in Francis turbine runner with splitter bladesin sandy water

    Directory of Open Access Journals (Sweden)

    Hua Hong

    2015-03-01

    Full Text Available As the key component of a hydroelectric power generation system, hydraulic turbine plays a decisive role in the overall performance of the system. There are many sandy rivers in the world, and turbines working in these rivers are seriously damaged. Therefore, the research of flow in sandy water has great theoretical significance and practical value. Based on the specific hydrological conditions of a hydropower station, the solid–liquid two-phase flow in the whole flow passage of a Francis turbine with splitter blades in sandy water was numerically studied. A geometric model of the whole flow passage of the Francis turbine was established on the basis of given design parameters. The solid–liquid two-phase turbulent flows in Francis turbine runner under three different loads were numerically analyzed by using this model. The three different loads are as follows: Condition 1: single unit with 1/4 load, Condition 2: single unit with 1/2 load, and Condition 3: single unit with full load. The distributions of pressure and sand concentration on the leading side and the suction side of the runner blades, as well as the velocity vector distribution of water and sand on the horizontal section of the runner, were obtained under different load conditions. Therefore, the damages to various flow passage components by sand can be qualitatively predicated under various conditions. To guarantee the safety and stability of the unit, the adverse conditions shall be avoided, which can provide certain reference for plant operation.

  14. AMS radiocarbon dating of medieval textile relics: The frocks and the pillow of St. Francis of Assisi

    Energy Technology Data Exchange (ETDEWEB)

    Fedi, M.E. [Dipartimento di Fisica dell' Universita di Firenze and INFN Sezione di Firenze, via Sansone 1, 50019 Sesto Fiorentino (Italy)], E-mail: fedi@fi.infn.it; Cartocci, A.; Taccetti, F.; Mando, P.A. [Dipartimento di Fisica dell' Universita di Firenze and INFN Sezione di Firenze, via Sansone 1, 50019 Sesto Fiorentino (Italy)

    2008-05-15

    Since natural textiles usually originate from short-lived organisms, they can represent a useful material to date samples from historical periods with a good accuracy. In this work, we present a set of radiocarbon measurements on medieval textile relics: two woollen habits and a pillow traditionally associated with St. Francis of Assisi, the saint patron of Italy. The strategy in choosing samples for radiocarbon dating is first discussed and the procedures for measurements - performed at the 3 MV Tandetron accelerator of Laboratorio di Tecniche Nucleari per i Beni Culturali (LABEC), Florence - are described; AMS results for the two frocks showed that only one of them, presently kept in the church of St. Francis in Cortona, is compatible with the Saint's period of life, as is the pillow also kept in Cortona. Another frock attributed to St. Francis appears to date from at least 80 years after his death. However, the goal of these measurements was not a bare authentication/disconfirmation of the relics; they just represent an example of how scientific analysis can integrate with humanistic studies. Indeed, AMS results, combined with a thorough analysis of the textiles typologies, confirmed the historical hypotheses based on documentary studies and on tradition. The overall conclusions contributed to the decisions taken for conservation, and have as a whole enhanced the religious importance of the relics.

  15. AMS radiocarbon dating of medieval textile relics: The frocks and the pillow of St. Francis of Assisi

    International Nuclear Information System (INIS)

    Fedi, M.E.; Cartocci, A.; Taccetti, F.; Mando, P.A.

    2008-01-01

    Since natural textiles usually originate from short-lived organisms, they can represent a useful material to date samples from historical periods with a good accuracy. In this work, we present a set of radiocarbon measurements on medieval textile relics: two woollen habits and a pillow traditionally associated with St. Francis of Assisi, the saint patron of Italy. The strategy in choosing samples for radiocarbon dating is first discussed and the procedures for measurements - performed at the 3 MV Tandetron accelerator of Laboratorio di Tecniche Nucleari per i Beni Culturali (LABEC), Florence - are described; AMS results for the two frocks showed that only one of them, presently kept in the church of St. Francis in Cortona, is compatible with the Saint's period of life, as is the pillow also kept in Cortona. Another frock attributed to St. Francis appears to date from at least 80 years after his death. However, the goal of these measurements was not a bare authentication/disconfirmation of the relics; they just represent an example of how scientific analysis can integrate with humanistic studies. Indeed, AMS results, combined with a thorough analysis of the textiles typologies, confirmed the historical hypotheses based on documentary studies and on tradition. The overall conclusions contributed to the decisions taken for conservation, and have as a whole enhanced the religious importance of the relics

  16. AMS radiocarbon dating of medieval textile relics: The frocks and the pillow of St. Francis of Assisi

    Science.gov (United States)

    Fedi, M. E.; Cartocci, A.; Taccetti, F.; Mandò, P. A.

    2008-05-01

    Since natural textiles usually originate from short-lived organisms, they can represent a useful material to date samples from historical periods with a good accuracy. In this work, we present a set of radiocarbon measurements on medieval textile relics: two woollen habits and a pillow traditionally associated with St. Francis of Assisi, the saint patron of Italy. The strategy in choosing samples for radiocarbon dating is first discussed and the procedures for measurements - performed at the 3 MV Tandetron accelerator of Laboratorio di Tecniche Nucleari per i Beni Culturali (LABEC), Florence - are described; AMS results for the two frocks showed that only one of them, presently kept in the church of St. Francis in Cortona, is compatible with the Saint's period of life, as is the pillow also kept in Cortona. Another frock attributed to St. Francis appears to date from at least 80 years after his death. However, the goal of these measurements was not a bare authentication/disconfirmation of the relics; they just represent an example of how scientific analysis can integrate with humanistic studies. Indeed, AMS results, combined with a thorough analysis of the textiles typologies, confirmed the historical hypotheses based on documentary studies and on tradition. The overall conclusions contributed to the decisions taken for conservation, and have as a whole enhanced the religious importance of the relics.

  17. Expected load spectra of prototype Francis turbines in low-load operation using numerical simulations and site measurements

    Science.gov (United States)

    Eichhorn, M.; Taruffi, A.; Bauer, C.

    2017-04-01

    The operators of hydropower plants are forced to extend the existing operating ranges of their hydraulic machines to remain competitive on the energy market due to the rising amount of wind and solar power. Faster response times and a higher flexibility towards part- and low-load conditions enable a better electric grid control and assure therefore an economic operation of the power plant. The occurring disadvantage is a higher dynamic excitation of affected machine components, especially Francis turbine runners, due to pressure pulsations induced by unsteady flow phenomena (e.g. draft tube vortex ropes). Therefore, fatigue analysis becomes more important even in the design phase of the hydraulic machines to evaluate the static and dynamic load in different operating conditions and to reduce maintenance costs. An approach including a one-way coupled fluid-structure interaction has been already developed using unsteady CFD simulations and transient FEM computations. This is now applied on two Francis turbines with different specific speeds and power ranges, to obtain the load spectra of both machines. The results are compared to strain gauge measurements on the according Francis turbines to validate the overall procedure.

  18. Don't Panic! | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... of this page please turn Javascript on. Feature: Phobias and Anxiety Disorders Don't Panic! Past Issues / Fall 2010 Table of Contents Phobias and other anxiety disorders affect millions of Americans. ...

  19. Hyperbaric Oxygen Therapy: Don't Be Misled

    Science.gov (United States)

    ... on Minorities Don't Be Fooled By Health Fraud Scams Beware of Illegally Marketed Diabetes Treatments Products ... feeds Follow FDA on Twitter Follow FDA on Facebook View FDA videos on YouTube View FDA photos ...

  20. Will 3552 Don Quixote escape from the Solar System?

    Directory of Open Access Journals (Sweden)

    Suryadi Siregar

    2011-05-01

    Full Text Available Asteroid 1983 SA, well known as 3552 Don Quixote, is one of Near Earth Asteroids (NEAs which is the most probable candidate for the cometary origin, or otherwise as Jupiter-Family-Comets (JFCs. The aim of this study is to investigate the possibility of 3552 Don Quixote to be ejected from the Solar System. This paper presents an orbital evolution of 100 hypothetical asteroids generated by cloning 3552 Don Quixote. Investigation of its orbital evolution is conducted by using the SWIFT subroutine package, where the gravitational perturbations of eight major planets in the Solar System are considered. Over very short time scales (220 kyr relative to the Solar System life time (10 Gyr, the asteroid 3552 Don Quixote gave an example of chaotic motion that can cause asteroid to move outward and may be followed by escaping from the Solar System. Probability of ejection within the 220 kyr time scale is 50%.

  1. Empirical investigation of the ethical reasoning of physicians and molecular biologists – the importance of the four principles of biomedical ethics

    Science.gov (United States)

    Ebbesen, Mette; Pedersen, Birthe D

    2007-01-01

    Background This study presents an empirical investigation of the ethical reasoning and ethical issues at stake in the daily work of physicians and molecular biologists in Denmark. The aim of this study was to test empirically whether there is a difference in ethical considerations and principles between Danish physicians and Danish molecular biologists, and whether the bioethical principles of the American bioethicists Tom L. Beauchamp and James F. Childress are applicable to these groups. Method This study is based on 12 semi-structured interviews with three groups of respondents: a group of oncology physicians working in a clinic at a public hospital and two groups of molecular biologists conducting basic research, one group employed at a public university and the other in a private biopharmaceutical company. Results In this sample, the authors found that oncology physicians and molecular biologists employed in a private biopharmaceutical company have the specific principle of beneficence in mind in their daily work. Both groups are motivated to help sick patients. According to the study, molecular biologists explicitly consider nonmaleficence in relation to the environment, the researchers' own health, and animal models; and only implicitly in relation to patients or human subjects. In contrast, considerations of nonmaleficence by oncology physicians relate to patients or human subjects. Physicians and molecular biologists both consider the principle of respect for autonomy as a negative obligation in the sense that informed consent of patients should be respected. However, in contrast to molecular biologists, physicians experience the principle of respect for autonomy as a positive obligation as the physician, in dialogue with the patient, offers a medical prognosis based upon the patients wishes and ideas, mutual understanding, and respect. Finally, this study discloses utilitarian characteristics in the overall conception of justice as conceived by oncology

  2. Empirical investigation of the ethical reasoning of physicians and molecular biologists – the importance of the four principles of biomedical ethics

    Directory of Open Access Journals (Sweden)

    Ebbesen Mette

    2007-10-01

    Full Text Available Abstract Background This study presents an empirical investigation of the ethical reasoning and ethical issues at stake in the daily work of physicians and molecular biologists in Denmark. The aim of this study was to test empirically whether there is a difference in ethical considerations and principles between Danish physicians and Danish molecular biologists, and whether the bioethical principles of the American bioethicists Tom L. Beauchamp and James F. Childress are applicable to these groups. Method This study is based on 12 semi-structured interviews with three groups of respondents: a group of oncology physicians working in a clinic at a public hospital and two groups of molecular biologists conducting basic research, one group employed at a public university and the other in a private biopharmaceutical company. Results In this sample, the authors found that oncology physicians and molecular biologists employed in a private biopharmaceutical company have the specific principle of beneficence in mind in their daily work. Both groups are motivated to help sick patients. According to the study, molecular biologists explicitly consider nonmaleficence in relation to the environment, the researchers' own health, and animal models; and only implicitly in relation to patients or human subjects. In contrast, considerations of nonmaleficence by oncology physicians relate to patients or human subjects. Physicians and molecular biologists both consider the principle of respect for autonomy as a negative obligation in the sense that informed consent of patients should be respected. However, in contrast to molecular biologists, physicians experience the principle of respect for autonomy as a positive obligation as the physician, in dialogue with the patient, offers a medical prognosis based upon the patients wishes and ideas, mutual understanding, and respect. Finally, this study discloses utilitarian characteristics in the overall conception of

  3. Francis Bacon and the "Interpretation of Nature" in the late Renaissance.

    Science.gov (United States)

    Serjeantson, Richard

    2014-12-01

    The "interpretation of nature" (interpretatio naturae) is the leading idea in Francis Bacon's natural philosophy. But by contrast with his ideas about method, induction, or experiment, the significance of the "interpretation of nature" has received very little scholarly attention. This essay tests the originality of Bacon's idea by means of a focused survey of existing forms of Renaissance natural knowledge-Aristotelian and anti-Aristotelian natural philosophy, Galenic and Paracelsian medicine, natural magic, physiognomy, natural history-before turning to consider the much more prominent place of "interpretation" in the fields of Renaissance logic, revealed and natural theology, and law. It finds that Bacon's application of the idea of "interpretation" to nature was highly original, but also that certain important aspects of his conception have analogies in Renaissance civil law. The essay concludes by exploring the implications of these findings for a recent body of scholarship in the history of the sciences that invokes the notion of the "interpretation of nature" to characterize pre-Baconian natural philosophy more generally.

  4. The “Visual Shock” of Francis Bacon: an essay in neuroesthetics

    Science.gov (United States)

    Zeki, Semir; Ishizu, Tomohiro

    2013-01-01

    In this paper we discuss the work of Francis Bacon in the context of his declared aim of giving a “visual shock.”We explore what this means in terms of brain activity and what insights into the brain's visual perceptive system his work gives. We do so especially with reference to the representation of faces and bodies in the human visual brain. We discuss the evidence that shows that both these categories of stimuli have a very privileged status in visual perception, compared to the perception of other stimuli, including man-made artifacts such as houses, chairs, and cars. We show that viewing stimuli that depart significantly from a normal representation of faces and bodies entails a significant difference in the pattern of brain activation. We argue that Bacon succeeded in delivering his “visual shock” because he subverted the normal neural representation of faces and bodies, without at the same time subverting the representation of man-made artifacts. PMID:24339812

  5. The mine and the furnace: Francis Bacon, Thomas Russell, and early Stuart mining culture.

    Science.gov (United States)

    Pastorino, Cesare

    2009-01-01

    Notwithstanding Francis Bacon's praise for the philosophical role of the mechanical arts, historians have often downplayed Bacon's connections with actual artisans and entrepreneurs. Addressing the specific context of mining culture, this study proposes a rather different picture. The analysis of a famous mining metaphor in The Advancement of Learning shows us how Bacon's project of reform of knowledge could find an apt correspondence in civic and entrepreneurial values of his time. Also, Bacon had interesting and so far unexplored links with the early modern English mining enterprises, like the Company of Mineral and Battery Works, ofwhich he was a shareholder. Moreover, Bacon's notes in a private notebook, Commentarius Solutus, and records of patents of invention, allow us to start grasping Bacon's connections with the metallurgist and entrepreneur Thomas Russell. Lastly, this paper argues that, to fully understand Bacon's links with the world of Stuart technicians and entrepreneurs, it is necessary to consider a different and insufficiently studied aspect of Bacon's interests, namely his work as patents referee while a Commissioner of Suits.

  6. The role of high cycle fatigue (HCF) onset in Francis runner reliability

    International Nuclear Information System (INIS)

    Gagnon, M; Tahan, S A; Bocher, P; Thibault, D

    2012-01-01

    High Cycle Fatigue (HCF) plays an important role in Francis runner reliability. This paper presents a model in which reliability is defined as the probability of not exceeding a threshold above which HCF contributes to crack propagation. In the context of combined Low Cycle Fatigue (LCF) and HCF loading, the Kitagawa diagram is used as the limit state threshold for reliability. The reliability problem is solved using First-Order Reliability Methods (FORM). A study case is proposed using in situ measured strains and operational data. All the parameters of the reliability problem are based either on observed data or on typical design specifications. From the results obtained, we observed that the uncertainty around the defect size and the HCF stress range play an important role in reliability. At the same time, we observed that expected values for the LCF stress range and the number of LCF cycles have a significant influence on life assessment, but the uncertainty around these values could be neglected in the reliability assessment.

  7. When sleep-related hypermotor epilepsy (SHE) met Charles Darwin and Francis Galton.

    Science.gov (United States)

    Parrino, Liborio; Pavesi, Giovanni

    2017-08-01

    Sleep-related hypermotor epilepsy (SHE) is characterized by short-lasting seizures patterned by repetitive and stereotyped motor events in the same person. In autosomal dominant SHE, genetic factors play a well-known key role. In The Expression of Emotions in Man and Animals, Charles Darwin quotes a plausible example of SHE illustrated by his cousin Sir Francis Galton: "the gentleman…lay fast asleep on his back in bed, raising his right arm slowly in front of his face, up to his forehead, and then dropping it with a jerk, so that the wrist fell heavily on the bridge of his nose. The trick did not occur every night, but occasionally, and was independent of any ascertained cause. Sometimes it was repeated incessantly for an hour or more." Similar manifestations during sleep occurred also in the patient's son and granddaughter, suggesting an autosomal inheritance without sex relationship. Differential diagnosis with REM behavior disorder and other parasomnias is discussed. To our knowledge, this could be the first description of a stereotyped SHE pattern with genetic transmission. © 2017 American Academy of Neurology.

  8. The 'root-brain' hypothesis of Charles and Francis Darwin: Revival after more than 125 years.

    Science.gov (United States)

    Baluska, Frantisek; Mancuso, Stefano; Volkmann, Dieter; Barlow, Peter W

    2009-12-01

    This year celebrates the 200(th) aniversary of the birth of Charles Darwin, best known for his theory of evolution summarized in On the Origin of Species. Less well known is that, in the second half of his life, Darwin's major scientific focus turned towards plants. He wrote several books on plants, the next-to-last of which, The Power of Movement of Plants, published together with his son Francis, opened plants to a new view. Here we amplify the final sentence of this book in which the Darwins proposed that: "It is hardly an exaggeration to say that the tip of the radicle thus endowed [with sensitivity] and having the power of directing the movements of the adjoining parts, acts like the brain of one of the lower animals; the brain being seated within the anterior end of the body, receiving impressions from the sense-organs, and directing the several movements." This sentence conveys two important messages: first, that the root apex may be considered to be a 'brain-like' organ endowed with a sensitivity which controls its navigation through soil; second, that the root apex represents the anterior end of the plant body. In this article, we discuss both these statements.

  9. Numerical Simulation and Validation of a High Head Model Francis Turbine at Part Load Operating Condition

    Science.gov (United States)

    Goyal, Rahul; Trivedi, Chirag; Kumar Gandhi, Bhupendra; Cervantes, Michel J.

    2017-07-01

    Hydraulic turbines are operated over an extended operating range to meet the real time electricity demand. Turbines operated at part load have flow parameters not matching the designed ones. This results in unstable flow conditions in the runner and draft tube developing low frequency and high amplitude pressure pulsations. The unsteady pressure pulsations affect the dynamic stability of the turbine and cause additional fatigue. The work presented in this paper discusses the flow field investigation of a high head model Francis turbine at part load: 50% of the rated load. Numerical simulation of the complete turbine has been performed. Unsteady pressure pulsations in the vaneless space, runner, and draft tube are investigated and validated with available experimental data. Detailed analysis of the rotor stator interaction and draft tube flow field are performed and discussed. The analysis shows the presence of a rotating vortex rope in the draft tube at the frequency of 0.3 times of the runner rotational frequency. The frequency of the vortex rope precession, which causes severe fluctuations and vibrations in the draft tube, is predicted within 3.9% of the experimental measured value. The vortex rope results pressure pulsations propagating in the system whose frequency is also perceive in the runner and upstream the runner.

  10. Numerical investigation of the air injection effect on the cavitating flow in Francis hydro turbine

    Science.gov (United States)

    Chirkov, D. V.; Shcherbakov, P. K.; Cherny, S. G.; Skorospelov, V. A.; Turuk, P. A.

    2017-09-01

    At full and over load operating points, some Francis turbines experience strong self-excited pressure and power oscillations. These oscillations are occuring due to the hydrodynamic instability of the cavitating fluid flow. In many cases, the amplitude of such pulsations may be reduced substantially during the turbine operation by the air injection/ admission below the runner. Such an effect is investigated numerically in the present work. To this end, the hybrid one-three-dimensional model of the flow of the mixture "liquid-vapor" in the duct of a hydroelectric power station, which was proposed previously by the present authors, is augmented by the second gaseous component — the noncondensable air. The boundary conditions and the numerical method for solving the equations of the model are described. To check the accuracy of computing the interface "liquid-gas", the numerical method was applied at first for solving the dam break problem. The algorithm was then used for modeling the flow in a hydraulic turbine with air injection below the runner. It is shown that with increasing flow rate of the injected air, the amplitude of pressure pulsations decreases. The mechanism of the flow structure alteration in the draft tube cone has been elucidated, which leads to flow stabilization at air injection.

  11. Experimental Investigation of Inter-Blade Vortices in a Model Francis Turbine

    Science.gov (United States)

    LIU, Demin; LIU, Xiaobing; ZHAO, Yongzhi

    2017-07-01

    The inter-blade vortex in a Francis turbine becomes one of the main hydraulic factors that are likely to cause blade erosion at deep part load operating conditions. However, the causes and the mechanism of inter-blade vortex are still under investigation according to present researches. Thus the causes of inter-blade vortex and the effect of different hydraulic parameters on the inter-blade vortex are investigated experimentally. The whole life cycle of the inter-blade vortex is observed by a high speed camera. The test results illustrate the whole life cycle of the inter-blade vortex from generation to separation and even to fading. It is observed that the inter-blade vortex becomes stronger with the decreasing of flow and head, which leads to pressure fluctuation. Meanwhile, the pressure fluctuations in the vane-less area and the draft tube section become stronger when inter-blade vortices exist in the blade channel. The turbine will be damaged if operating in the inter-blade vortex zone, so its operating range must be far away from that zone. This paper reveals the main cause of the inter-blade vortex which is the larger incidence angle between the inflow angle and the blade angle on the leading edge of the runner at deep part load operating conditions.

  12. Experiences with the hydraulic design of the high specific speed Francis turbine

    International Nuclear Information System (INIS)

    Obrovsky, J; Zouhar, J

    2014-01-01

    The high specific speed Francis turbine is still suitable alternative for refurbishment of older hydro power plants with lower heads and worse cavitation conditions. In the paper the design process of such kind of turbine together with the results comparison of homological model tests performed in hydraulic laboratory of ČKD Blansko Engineering is introduced. The turbine runner was designed using the optimization algorithm and considering the high specific speed hydraulic profile. It means that hydraulic profiles of the spiral case, the distributor and the draft tube were used from a Kaplan turbine. The optimization was done as the automatic cycle and was based on a simplex optimization method as well as on a genetic algorithm. The number of blades is shown as the parameter which changes the resulting specific speed of the turbine between n s =425 to 455 together with the cavitation characteristics. Minimizing of cavitation on the blade surface as well as on the inlet edge of the runner blade was taken into account during the design process. The results of CFD analyses as well as the model tests are mentioned in the paper

  13. Experiences with the hydraulic design of the high specific speed Francis turbine

    Science.gov (United States)

    Obrovsky, J.; Zouhar, J.

    2014-03-01

    The high specific speed Francis turbine is still suitable alternative for refurbishment of older hydro power plants with lower heads and worse cavitation conditions. In the paper the design process of such kind of turbine together with the results comparison of homological model tests performed in hydraulic laboratory of ČKD Blansko Engineering is introduced. The turbine runner was designed using the optimization algorithm and considering the high specific speed hydraulic profile. It means that hydraulic profiles of the spiral case, the distributor and the draft tube were used from a Kaplan turbine. The optimization was done as the automatic cycle and was based on a simplex optimization method as well as on a genetic algorithm. The number of blades is shown as the parameter which changes the resulting specific speed of the turbine between ns=425 to 455 together with the cavitation characteristics. Minimizing of cavitation on the blade surface as well as on the inlet edge of the runner blade was taken into account during the design process. The results of CFD analyses as well as the model tests are mentioned in the paper.

  14. The Catholic Bishops in the U.S. Public Arena: Changing Prospects under Pope Francis

    Directory of Open Access Journals (Sweden)

    Richard L. Wood

    2016-02-01

    Full Text Available The public profile of the Roman Catholic bishops of the United States results not simply from their own interventions in political life, but from the broad array of actions and actors within “public Catholicism” broadly conceived. This article assesses the contemporary profile of the American bishops from this broad angle, particularly in light of new dynamics under the papacy of Francis I. It does so by documenting public Catholicism’s presence in ecclesial institutions, other public institutions, and lay-centered social movements (particularly faith-based community organizing and via a case study of the healthcare reform debate around the State Children’s Health Insurance Program and the Affordable Care Act. Cultural and institutional factors shaping Catholic public presence are analyzed in three dimensions of social life: institutional leadership; authority dynamics within the Church; and the culture of prayer, spirituality, and worship in parishes. Finally, the conclusion discusses the key dynamics likely to shape the future of public Catholicism in America.

  15. Simulation of the Francis-99 Hydro Turbine During Steady and Transient Operation

    Science.gov (United States)

    Dewan, Yuvraj; Custer, Chad; Ivashchenko, Artem

    2017-01-01

    Numerical simulation of the Francis-99 hydroturbine with correlation to experimental measurements are presented. Steady operation of the hydroturbine is analyzed at three operating conditions: the best efficiency point (BEP), high load (HL), and part load (PL). It is shown that global quantities such as net head, discharge and efficiency are well predicted. Additionally, time-averaged velocity predictions compare well with PIV measurements obtained in the draft tube immediately downstream of the runner. Differences in vortex rope structure between operating points are discussed. Unsteady operation of the hydroturbine from BEP to HL and from BEP to PL are modeled. It is shown that simulation methods used to model the steady operation produce predictions that correlate well with experiment for transient operation. Time-domain unsteady simulation is used for both steady and unsteady operation. The full-fidelity geometry including all components is meshed using an unstructured polyhedral mesh with body-fitted prism layers. Guide vane rotation for transient operation is imposed using fully-conservative, computationally efficient mesh morphing. The commercial solver STAR-CCM+ is used for all portions of the analysis including meshing, solving and post-processing.

  16. Applying Turbulence Models to Hydroturbine Flows: A Sensitivity Analysis Using the GAMM Francis Turbine

    Science.gov (United States)

    Lewis, Bryan; Cimbala, John; Wouden, Alex

    2011-11-01

    Turbulence models are generally developed to study common academic geometries, such as flat plates and channels. Creating quality computational grids for such geometries is trivial, and allows stringent requirements to be met for boundary layer grid refinement. However, engineering applications, such as flow through hydroturbines, require the analysis of complex, highly curved geometries. To produce body-fitted grids for such geometries, the mesh quality requirements must be relaxed. Relaxing these requirements, along with the complexity of rotating flows, forces turbulence models to be employed beyond their developed scope. This study explores the solution sensitivity to boundary layer grid quality for various turbulence models and boundary conditions currently implemented in OpenFOAM. The following models are resented: k-omega, k-omega SST, k-epsilon, realizable k-epsilon, and RNG k-epsilon. Standard wall functions, adaptive wall functions, and sub-grid integration are compared using various grid refinements. The chosen geometry is the GAMM Francis Turbine because experimental data and comparison computational results are available for this turbine. This research was supported by a grant from the DoE and a National Defense Science and Engineering Graduate Fellowship.

  17. A Parametric Study of Unsteady Rotor-Stator Interaction in a Simplified Francis Turbine

    Science.gov (United States)

    Wouden, Alex; Cimbala, John; Lewis, Bryan

    2011-11-01

    CFD analysis is becoming a critical stage in the design of hydroturbines. However, its capability to represent unsteady flow interactions between the rotor and stator (which requires a 360-degree, mesh-refined model of the turbine passage) is hindered. For CFD to become a more effective tool in predicting the performance of a hydroturbine, the key interactions between the rotor and stator need to be understood using current numerical methods. As a first step towards evaluating this unsteady behavior without the burden of a computationally expensive domain, the stator and Francis-type rotor blades are reduced to flat plates. Local and global variables are compared using periodic, semi-periodic, and 360-degree geometric models and various turbulence models (k-omega, k-epsilon, and Spalart-Allmaras). The computations take place within the OpenFOAM® environment and utilize a general grid interface (GGI) between the rotor and stator computational domains. The rotor computational domain is capable of dynamic rotation. The results demonstrate some of the strengths and limitations of utilizing CFD for hydroturbine analysis. These case studies will also serve as tutorials to help others learn how to use CFD for turbomachinery. This research is funded by a grant from the DOE.

  18. Experimental Investigation on the Characteristics of Hydrodynamic Stabilities in Francis Hydroturbine Models

    Directory of Open Access Journals (Sweden)

    Wen-Tao Su

    2014-03-01

    Full Text Available This paper presents an experimental investigation of flow phenomena related to the characteristic frequencies of pressure fluctuation in Francis hydroturbine models. The experiments were carried out on two test rigs with two model runners having hydraulic similarities. Flow field around the guide vanes was measured with a particle image velocimetry (PIV on the first PIV test rig. Flow structures at the inlet region of runner and in draft tube at different operating conditions were visualized on another hydrodynamic test rig. Analyses of dominant frequency of unsteady hydraulic behaviors in the tested hydroturbines were performed. It was observed that the main frequency of flow over the guide vanes and the dominant frequency of channel vortex equal the blade passing frequency; the dominant frequency of flow separation at the suction side of blade inlet equals the vane passing frequency; the vortex rope in the draft tube displays a low-frequency nature. The flow instabilities and fluctuations directly influence the running of hydroturbine, thus these experimental results could provide important evidence for the stability study of a real hydroturbine.

  19. Laboratory modeling of flow regimes in a draft tube of Francis hydro-turbine

    Directory of Open Access Journals (Sweden)

    Shtork Sergey

    2017-01-01

    Full Text Available The paper reports on some results of the experimental study of flow and pressure pulsations in a laboratory model of the draft tube (DT of Francis-99 hydro-turbine over a broad range of operating regimes. Velocity distributions at the model inlet varied within 866 modes of the turbine load conditions, including those with maximum coherent pressure pulsations on the model walls. The contact and non-contact methods were used to measure pressure pulsations on the model walls using acoustic sensors and to measure the averaged velocity distribution with a laser Doppler anemometer “LAD-06i”. Analysis of the results have showed that in the model cone there are flow modes with forming of precessing vortex cores, accompanied by a sharp increase in the amplitude of coherent pressure pulsations on the wall and the velocity field rearrangement. It is shown that the vortex core starts forming with an increase in the integral parameter of swirl up to S>0.5. A novelty of the work is the combination of the rapid prototyping (3-d printing of the inflow swirl generators and computerized measurement techniques that makes it possible to acquire rapidly a large amount of experimental data for a variety of designs and operating conditions. The results can provide insight into the effect of various design and operating parameters on the flow physics, as well as serve for verification of the numerical simulations.

  20. Deciphering the language of nature: cryptography, secrecy, and alterity in Francis Bacon.

    Science.gov (United States)

    Clody, Michael C

    2011-01-01

    The essay argues that Francis Bacon's considerations of parables and cryptography reflect larger interpretative concerns of his natural philosophic project. Bacon describes nature as having a language distinct from those of God and man, and, in so doing, establishes a central problem of his natural philosophy—namely, how can the language of nature be accessed through scientific representation? Ultimately, Bacon's solution relies on a theory of differential and duplicitous signs that conceal within them the hidden voice of nature, which is best recognized in the natural forms of efficient causality. The "alphabet of nature"—those tables of natural occurrences—consequently plays a central role in his program, as it renders nature's language susceptible to a process and decryption that mirrors the model of the bilateral cipher. It is argued that while the writing of Bacon's natural philosophy strives for literality, its investigative process preserves a space for alterity within scientific representation, that is made accessible to those with the interpretative key.

  1. From medicine to natural philosophy: Francis Hauksbee's way to the air-pump.

    Science.gov (United States)

    Brundtland, Terje

    2008-06-01

    Francis Hauksbee (1660-1713) is well known for his double-barrelled air-pump. However, the origin of this pump, and Hauksbee's background, are often described as a mystery. This text seeks to dispel the riddle. It is argued that Hauksbee's competence as an exceptional maker of air-pumps was developed between 1699 and 1703 as a result of his experiences with the construction, manufacturing and sale of cupping-glasses. His cupping utensils embodied a new design, where syringes were used to evacuate the glasses, instead of the traditional way by fire or mouth suction. These syringes, which in fact were small air-pumps, were perfected between 1699 and 1701. A larger syringe, introduced in 1701, served as a transition from the cupping-syringe to his first air-pump for use in natural philosophy. This syringe was described as a 'combined engine', which could serve as an air-pump, a condensing engine and a syringe for injecting air, wax or mercury into pathological specimens. Hauksbee's first air-pump was a single-barrelled model introduced in 1702, based on the combined engine. Its various features, such as easy and convenient leak-tightening, exact pressure measurements by an in-built barometer and an air-inlet function for readmission of air into the receiver, are discussed. Finally, it is shown that these activities gave Hauksbee the reputation of being an outstanding instrument-maker, years before the double-barrelled air-pump was in sight.

  2. Experimental Hydro-Mechanical Characterization of Full Load Pressure Surge in Francis Turbines

    Science.gov (United States)

    Müller, A.; Favrel, A.; Landry, C.; Yamamoto, K.; Avellan, F.

    2017-04-01

    Full load pressure surge limits the operating range of hydro-electric generating units by causing significant power output swings and by compromising the safety of the plant. It appears during the off-design operation of hydraulic machines, which is increasingly required to regulate the broad integration of volatile renewable energy sources into the existing power network. The underlying causes and governing physical mechanisms of this instability were investigated in the frame of a large European research project and this paper documents the main findings from two experimental campaigns on a reduced scale model of a Francis turbine. The multi-phase flow in the draft tube is characterized by Particle Image Velocimetry, Laser Doppler Velocimetry and high-speed visualizations, along with synchronized measurements of the relevant hydro-mechanical quantities. The final result is a comprehensive overview of how the unsteady draft tube flow and the mechanical torque on the runner shaft behave during one mean period of the pressure oscillation, thus defining the unstable fluid-structure interaction responsible for the power swings. A discussion of the root cause is initiated, based on the state of the art. Finally, the latest results will enable a validation of recent RANS flow simulations used for determining the key parameters of hydro-acoustic stability models.

  3. Investigation of a High Head Francis Turbine at Runaway Operating Conditions

    Directory of Open Access Journals (Sweden)

    Chirag Trivedi

    2016-03-01

    Full Text Available Hydraulic turbines exhibit total load rejection during operation because of high fluctuations in the grid parameters. The generator reaches no-load instantly. Consequently, the turbine runner accelerates to high speed, runaway speed, in seconds. Under common conditions, stable runaway is only reached if after a load rejection, the control and protection mechanisms both fail and the guide vanes cannot be closed. The runner life is affected by the high amplitude pressure loading at the runaway speed. A model Francis turbine was used to investigate the consequences at the runaway condition. Measurements and simulations were performed at three operating points. The numerical simulations were performed using standard k-ε, k-ω shear stress transport (SST and scale-adaptive simulation (SAS models. A total of 12.8 million hexahedral mesh elements were created in the complete turbine, from the spiral casing inlet to the draft tube outlet. The experimental and numerical analysis showed that the runner was subjected to an unsteady pressure loading up to three-times the pressure loading observed at the best efficiency point. Investigates of unsteady pressure pulsations at the vaneless space, runner and draft tube are discussed in the paper. Further, unsteady swirling flow in the blade passages was observed that was rotating at a frequency of 4.8-times the runaway runner angular speed. Apart from the unsteady pressure loading, the development pattern of the swirling flow in the runner is discussed in the paper.

  4. Water hammer effect in the spiral case and penstock of Francis turbines

    Science.gov (United States)

    Pepa, D.; Ursoniu, C.; Gillich, R. N.; Campian, C. V.

    2017-01-01

    Sudden pressure increases in the penstock or spiral case of a hydraulic turbine are the effect of sudden flow variation that occur during transient processes of type opening / closing or load rejection of the hydro unit. The consequence of the pressure rise in the spiral case and penstock is the water hammer phenomenon, whose effects can be devastating in some cases, up to breaking pipes and calamities produced in the area. This paper aims to analyze the method of calculation of the maximum pressure values that might occur in load rejection situations to a hydraulic turbine, in spiral case and in penstock, conditioned by the limiting of the values of the over speed and measures of limiting the increase in pressure in conjunction with limiting the increase in speed in these specific processes. As an example, we studied and analyzed the situation of a hydroelectric power plant equipped with a 7.8 MW Francis turbine without pressure regulator and the inflow surge. The results of analytical calculation overlaid on the experimental measurements performed during the performance tests of the hydro unit lead to the conclusion that the calculation algorithm proposed has been chosen correctly and the 2-stage closing law of the wicket gate promoted in this case is effective in such situations.

  5. Predicting the performance of a high head Francis turbine using a fully implicit mixing plane

    International Nuclear Information System (INIS)

    Amstutz, O; Aakti, B; Casartelli, E; Mangani, L; Hanimann, L

    2015-01-01

    In the present paper numerical investigations of a complete high head Francis turbine comprehensive of a spiral casing, stay and guide vanes and draft tube have been performed at three operating conditions, namely at part load (PL), best efficiency point (BEP), and high load (HL). The main target of the investigations is to assess the prediction accuracy of a reduced domain of the complete turbine using a novel mixing-plane formulation. The computational domain is simplified simulating one single passage of the runner, thus assuming rotational periodicity and steady state conditions. The results were compared with experimental data published by the workshop organization. All CFD simulations were performed at model scale with an in-house adapted, 3D, unstructured, object-oriented finite volume code based on the OpenFOAM-V2.2 framework and designed to solve steady-state incompressible RANS-Equations. The pressure-based solver uses a SIMPLE-C like algorithm and is capable of handling multiple references of frame (MRF). The influence of the turbulence has been considered applying the shear-stress transport model (SST). Full second order upwind scheme for advection discretization has been used for all computations

  6. The Metabolic Fate of Deoxynivalenol and Its Acetylated Derivatives in a Wheat Suspension Culture: Identification and Detection of DON-15-O-Glucoside, 15-Acetyl-DON-3-O-Glucoside and 15-Acetyl-DON-3-Sulfate

    Directory of Open Access Journals (Sweden)

    Clemens Schmeitzl

    2015-08-01

    Full Text Available Deoxynivalenol (DON is a protein synthesis inhibitor produced by the Fusarium species, which frequently contaminates grains used for human or animal consumption. We treated a wheat suspension culture with DON or one of its acetylated derivatives, 3-acetyl-DON (3-ADON, 15-acetyl-DON (15-ADON and 3,15-diacetyl-DON (3,15-diADON, and monitored the metabolization over a course of 96 h. Supernatant and cell extract samples were analyzed using a tailored LC-MS/MS method for the quantification of DON metabolites. We report the formation of tentatively identified DON-15-O-β-D-glucoside (D15G and of 15-acetyl-DON-3-sulfate (15-ADON3S as novel deoxynivalenol metabolites in wheat. Furthermore, we found that the recently identified 15-acetyl-DON-3-O-β-D-glucoside (15-ADON3G is the major metabolite produced after 15-ADON challenge. 3-ADON treatment led to a higher intracellular content of toxic metabolites after six hours compared to all other treatments. 3-ADON was exclusively metabolized into DON before phase II reactions occurred. In contrast, we found that 15-ADON was directly converted into 15-ADON3G and 15-ADON3S in addition to metabolization into deoxynivalenol-3-O-β-D-glucoside (D3G. This study highlights significant differences in the metabolization of DON and its acetylated derivatives.

  7. Computation and analysis of cavitating flow in Francis-class hydraulic turbines

    Science.gov (United States)

    Leonard, Daniel J.

    Hydropower is the most proven renewable energy technology, supplying the world with 16% of its electricity. Conventional hydropower generates a vast majority of that percentage. Although a mature technology, hydroelectric generation shows great promise for expansion through new dams and plants in developing hydro countries. Moreover, in developed hydro countries, such as the United States, installing generating units in existing dams and the modern refurbishment of existing plants can greatly expand generating capabilities with little to no further impact on the environment. In addition, modern computational technology and fluid dynamics expertise has led to substantial improvements in modern turbine design and performance. Cavitation has always presented a problem in hydroturbines, causing performance breakdown, erosion, damage, vibration, and noise. While modern turbines are usually designed to be cavitation-free at their best efficiency point, due to the variable demand of the energy market it is fairly common to operate at off-design conditions. Here, cavitation and its deleterious effects are unavoidable, and hence, cavitation is a limiting factor on the design and operation of these turbines. Multiphase Computational Fluid Dynamics (CFD) has been used in recent years to model cavitating flow for a large range of problems, including turbomachinery. However, CFD of cavitating flow in hydroturbines is still in its infancy. This dissertation presents steady-periodic Reynolds-averaged Navier-Stokes simulations of a cavitating Francis-class hydroturbine at model and prototype scales. Computational results of the reduced-scale model and full-scale prototype, undergoing performance breakdown, are compared with empirical model data and prototype performance estimations based on standard industry scalings from the model data. Mesh convergence of the simulations is also displayed. Comparisons are made between the scales to display that cavitation performance breakdown

  8. Don Gonzalo Jimenez de Quesada. El Fundador

    Directory of Open Access Journals (Sweden)

    Alvaro López Pardo

    1989-09-01

    Full Text Available

    Discurso pronunciado por el Doctor Alvaro López Pardo Presidente de la Academia de Historia de Bogotá, al Consejo de Bogotá el día 6 de agosto de 1988. Sesión especial de los 450 años.

    Por el año de 1578, caminaba lentamente por las polvorientas calles del poblado de Mariquita, un anciano, casi octogenario, que mostraba en su piel huellas de un enfermedad que se decía era la de San Lázaro.

    Las gentes lo miraban pasar con una mezcla de respeto y de piedad. En su mirada, un tanto vaga, se podían apreciar destellos de la que fuera una recia personalidad. Esta pobre figura era nadie menos que el Mariscal Don Gonzalo Jiménez de Quesada.

    En esta población ardiente y lejana, cargado de deudas, sin techo propio, iba a morir el gran señor, el Gran Capitán, el Gran Aventurero que fundara ésta nuestra noble y muy leal Santa Fe de Bogotá, cuyos 450 años celebramos en este día.

    Parece increíble que en aquella época y con una agitada vida, Don Gonzalo hubiera llegado a tan avanzada edad, es muestra de la fuerza de una raza y del templo de su espíritu, que se sobreponía a todas las adversidades y contratiempos.

    ¿Qué recuerdos vendrían a la mente de este anciano cuando, sentado en una pobre silla de vaqueta, contempla el azul cielo del trópico? ¿Quizá su infancia en España, en Córdoba, donde naciera o en la imponente Granada de los moros, recuperada hacía unos años por la Reina Isabel. Viendo los jardines de la Alhambra, el Generalife y al fondo el blanco perpetuo de la Sierra Nevada. O vendría a su mente el paso del fúnebre cortejo de Felipe el Hermoso y su lunática viuda Doña Juana?

    Sería tal vez el periodo de su juventud, oyendo las aventuras de Cortés en la Conquista de México, en medio de una Europa convulsionada y con España como centro de la misma. O quizás cuando estudiaba leyes en Salamanca y se metía en pleitos que no siempre ganaba y como

  9. Numerical Simulation of the Francis Turbine and CAD used to Optimized the Runner Design (2nd).

    Science.gov (United States)

    Sutikno, Priyono

    2010-06-01

    , medium head Francis type, with following value for the most important parameter, the rated specific speed ns.

  10. Sobre as afinidades entre a filosofia de Francis Bacon e o ceticismo

    Directory of Open Access Journals (Sweden)

    Luiz A. A. Eva

    2006-06-01

    Full Text Available Este texto se ocupa de um exame, em caráter introdutório, das relações entre a reflexão de Bacon acerca das limitações de nossas faculdades e o ceticismo filosófico - um tema pouco considerado pela literatura mais recente, a despeito das muitas referências a tal filosofia. Ainda que, à primeira vista, tais referências possam parecer vagas e imprecisas, pensamos que um exame adequado de algumas delas pode revelar, não apenas a importância do tema para a compreensão de aspectos do seu próprio empreendimento, mas o interesse de Bacon pela literatura cética contemporânea. As peculiaridades de sua própria interpretação, por sua vez, parecem antecipar traços do modo como essa filosofia foi compreendida por filósofos posteriores, como Hume.This text focuses, in a preliminary way, on the relations between Francis Bacon's reflections on the limits of our cognitive faculties and philosophical skepticism, a theme not much considered by most of recent commentaries, in spite of Bacon's own explicit and numerous allusions to this philosophy. Even if these allusions seem at first sight somewhat loose and not very sharp, some of them reveal, we think, not only its relevance for understanding of some aspects of his own enterprise, but also Bacon's attention to the skeptical literature produced on the period. Moreover, the particularities of his own interpretation of skepticism seem to anticipate important features of the way this philosophy was understood by later philosophers as Hume.

  11. Two-phase simulations of the full load surge in Francis turbines

    Science.gov (United States)

    Wack, J.; Riedelbauch, S.

    2016-11-01

    At off-design conditions, Francis turbines experience cavitation which may reduce the power output and can cause severe damage in the machine. Certain conditions can cause self-excited oscillations of the vortex rope in the draft tube at full load operating point. For the presented work, two-phase simulations are carried out at model scale on a domain ranging from the inlet of the spiral case to the outlet of the draft tube. At different locations, wall pressure measurements are available and compared to the simulation results. Furthermore, the dynamics of the cavity volume in the draft tube cone and at the trailing edge of the runner blades are investigated by comparing with high speed visualization. To account for the selfexcited behaviour, proper boundary conditions need to be set. In this work, the focus lies on the treatment of the boundary condition at the inlet. In the first step, the dynamic behaviour of the cavity regions is investigated using a constant mass flow. Thereafter, oscillations of the total pressure and mass flow rate are prescribed using various frequencies and amplitudes. This methodology enables to examine the response of the cavity dynamics due to different excitations. It can be observed that setting a constant mass flow boundary condition is not suitable to account for the self-excited behaviour. Prescribing the total pressure has the result that the frequency of the vapour volume oscillation is the same as the frequency of the excitation signal. Contrary to that, for an excitation with a mass flow boundary condition, the response of the system is not equal to the excitation.

  12. Francis Crick, cross-worlds influencer: A narrative model to historicize big bioscience.

    Science.gov (United States)

    Aicardi, Christine

    2016-02-01

    The essay is an empirical case study of famed British scientist Francis Crick. Viewing him as a 'cross-worlds influencer' who was moreover dedicated to a cause, I have tried to understand how these two characteristics influenced the trajectory of his long career and how they shaped his contributions to the diverse research fields in which he was active, and concluded that these characteristics reconfigure Crick's career into a coherent whole. First, I identify a major thread running through Crick's career: helping organise 'un-disciplined' new research fields, and show that his successive choices were not serendipitous but motivated by what he construed as a crusade against 'vitalism': anti-vitalism was a defining driver of his career. I then examine how Crick put his skills as a crossworlds influencer to the service of his cause, by helping organise his chosen fields of intervention. I argue that his activities as a cross-worlds influencer were an integral part of his way of 'doing science' and that his contributions to science, neuroscience in particular, should be re-evaluated in this light. This leads me to advance a possible strategy for historians to investigate big bioscience fields. Following Abir-Am, I propose to trace their genealogies back to the fluctuating semi-institutional gatherings and the institutional structures that sustained them. My research on Crick supports the view that such studies can bring insights into the question of why the contours of contemporary big bioscience endeavours have come to be shaped the way they are. Further, the essay provides a heuristic device for approaching these enquiries: 'follow the cross-worlds influencers' who worked to build and organise these semi-institutional gatherings and institutional structures. Copyright © 2015 The Author. Published by Elsevier Ltd.. All rights reserved.

  13. Francis Crick, cross-worlds influencer: A narrative model to historicize big bioscience

    Science.gov (United States)

    Aicardi, Christine

    2016-01-01

    The essay is an empirical case study of famed British scientist Francis Crick. Viewing him as a ‘cross-worlds influencer’ who was moreover dedicated to a cause, I have tried to understand how these two characteristics influenced the trajectory of his long career and how they shaped his contributions to the diverse research fields in which he was active, and concluded that these characteristics reconfigure Crick's career into a coherent whole. First, I identify a major thread running through Crick's career: helping organise ‘un-disciplined’ new research fields, and show that his successive choices were not serendipitous but motivated by what he construed as a crusade against ‘vitalism’: anti-vitalism was a defining driver of his career. I then examine how Crick put his skills as a crossworlds influencer to the service of his cause, by helping organise his chosen fields of intervention. I argue that his activities as a cross-worlds influencer were an integral part of his way of ‘doing science’ and that his contributions to science, neuroscience in particular, should be re-evaluated in this light. This leads me to advance a possible strategy for historians to investigate big bioscience fields. Following Abir-Am, I propose to trace their genealogies back to the fluctuating semi-institutional gatherings and the institutional structures that sustained them. My research on Crick supports the view that such studies can bring insights into the question of why the contours of contemporary big bioscience endeavours have come to be shaped the way they are. Further, the essay provides a heuristic device for approaching these enquiries: ‘follow the cross-worlds influencers’ who worked to build and organise these semi-institutional gatherings and institutional structures. PMID:26383132

  14. The Origin of DIRT (Detrital Input and Removal Treatments): the Legacy of Dr. Francis D. Hole

    Science.gov (United States)

    Townsend, K. L.; Lajtha, K.; Caldwell, B.; Sollins, P.

    2007-12-01

    Soil organic matter (SOM) plays a key role in the cycling and retention of nitrogen and carbon within soil. Both above and belowground detrital inputs determine the nature and quantity of SOM. Studies on detrital impacts on SOM dynamics are underway at several LTER, ILTER and LTER-affiliated sites using a common experimental design, Detrital Input and Removal Treatments (DIRT). The concept for DIRT was originally based on experimental plots established at the University of Wisconsin Arboretum by Dr. Francis D. Hole in 1956 to study the effects of detrital inputs on pedogenesis. These plots are located on two forested sites and two prairie sites within the arboretum. Manipulations of the forested sites include double litter, no litter and removal of the O and A horizons. Manipulations of the prairie sites include harvest, mulch, bare and burn. These original treatments have largely been maintained since 1956. After 40 years of maintenance, there were significant differences in soil carbon between the double and no litter plots. The double litter plots had increased by nearly 30% while the no litter plots had decreased over 50%. The original DIRT plots are now 50 years old and have been re-sampled, where possible, for total carbon and nitrogen, labile and recalcitrant carbon fractions, net and gross nitrogen mineralization rates, and SOM bioavailability through CO2 respiration. The soils were fractionated by density to examine the role of carbon in each density fraction. The mean age of carbon in each fraction was determined by radiocarbon dating. This sampling and analysis is of special significance because it provides a glimpse into the future SOM trajectories for the new DIRT sites: Harvard Forest (MA), Bousson (PA), Andrews Experimental Forest (OR) and Sikfokut (Hungary).

  15. Motivating Tomorrow's Biologists

    Science.gov (United States)

    Musante, Susan

    2012-01-01

    The story of biology is far more complex and fascinating than straightforward facts or neatly labeled diagrams of structures and systems. Although exams can motivate students, the key to using these extrinsic motivators to increase student understanding lies in the way the assessments are designed and what they measure. Those involved in…

  16. [Spanish neuroscience in times of Don Quixote].

    Science.gov (United States)

    Martín-Araguz, Antonio; Mikola, Yvett; Almendral-Doncel, Raquel; Campos-Bueno, Javier

    2016-02-16

    Miguel de Cervantes Saavedra published his immortal work Don Quixote of La Mancha in a time of crisis and decadence in Spain that occurred during the transition between the 16th and 17th centuries. In 2016 we commemorate the fourth centenary of the death of our distinguished man of letters, and thus in this article we analyse the status of Hispanic neuroscience, both in the Quixote itself and in other works by the most significant contemporary writers of that time. Despite the adverse historical circumstances, the shift from the Renaissance to the Baroque periods, in the Crown of Castile, was a flourishing period for literature (Spanish Golden Age) and other Hispanic arts (painting, sculpture, architecture and music), as well as bearing witness to a prodigious creativity in the field of neuroscience, including the field of natural philosophy. In his book Antoniana Margarita the physician Gomez Pereira laid the foundations for brain mechanism and the concept of conditioned reflexes several decades ahead of his time. The apothecary Miguel Sabuco also anticipated the concept of neurotransmission centuries ahead of his time in his New Philosophy. The physician Juan Huarte de San Juan was the founder of neuropsychology and experimental psychology, and his Examination of Men's Wits has been one of the most influential and widely translated scientific texts of all times. Its concepts are clearly reflected in Cervantes' Quixote. This analysis of Cervantes' work within the cultural setting of the book is intended as a homage to the immortal figure of our 'Prince of Wits' in the fourth centenary of his death.

  17. Natural knowledge as a propaedeutic to self-betterment: Francis Bacon and the transformation of natural history.

    Science.gov (United States)

    Lancaster, James A T

    2012-01-01

    This paper establishes the 'emblematic' use of natural history as a propaedeutic to self-betterment in the Renaissance; in particular, in the natural histories of Gessner and Topsell, but also in the works of Erasmus and Rabelais. Subsequently, it investigates how Francis Bacon's conception of natural history is envisaged in relation to them. The paper contends that, where humanist natural historians understood the use of natural knowledge as a preliminary to individual improvement, Bacon conceived self-betterment foremost as a means to Christian charity, or social-betterment. It thus examines the transformation of the moralizing aspect of Renaissance natural history in Bacon's conception of his Great Instauration.

  18. Abortion, metaphysics and morality: a review of Francis Beckwith's defending life: a moral and legal case against abortion choice.

    Science.gov (United States)

    Nobis, Nathan

    2011-06-01

    In Defending Life: A Moral and Legal Case Against Abortion Choice (2007) and an earlier article in this journal, "Defending Abortion Philosophically"(2006), Francis Beckwith argues that fetuses are, from conception, prima facie wrong to kill. His arguments are based on what he calls a "metaphysics of the human person" known as "The Substance View." I argue that Beckwith's metaphysics does not support his abortion ethic: Moral, not metaphysical, claims that are part of this Substance View are the foundation of the argument, and Beckwith inadequately defends these moral claims. Thus, Beckwith's arguments do not provide strong support for what he calls the "pro-life" view of abortion.

  19. Viajando con Don Quijote en el siglo XXI

    Directory of Open Access Journals (Sweden)

    Odilíe Rojas-López

    2006-06-01

    Full Text Available Don Quixote has ridden with us for a long time now, and as if his fight against windmills were not enough, Don Quixote still has many more difficult situations to combat in the present times. Will the Knight of the Sad Figure accomplish this new deed? It is our challenge to find an answer to this inquiry. For this purpose, the author of this essay inserts the Knight of the Sad Figure in XXI century society. The author transforms the values, costumes and points of view of the times of the literary piece and establishes a series of relationships between the literary text, the main character and several current daily life situations. Don Quixote will certainly continue his fight against all the conditions we encounter nowadays. There is no doubt, then, that this knight still lives among us.

  20. Dostoyevski and Don Quijote: Poetics and Aesthetics of a Delusion

    Directory of Open Access Journals (Sweden)

    Tamara Djermanovic

    2015-12-01

    Full Text Available In Fedor Mikhailovich Dostoevsky’s body of work (1821-1881 one can find more than thirty references to Don Quixote; while some of them allude to the novel of Don Quixote itself, other ones refer to Cervantes’ hero as an archetypal figure. Since decades ago, the Russian literary criticism has been interested in the Russian quixotism – including Dostoevsky’s work – and important studies on this subject have been published recently. This study follows Dostoevsky’s references on La Mancha’s Knight as an independent figure of Cervantes’ novel, and the different symbolism Don Quixote’s figure has had in both Russian people and Russian intelligentsia.

  1. Distributed Observer Network (DON), Version 3.0, User's Guide

    Science.gov (United States)

    Mazzone, Rebecca A.; Conroy, Michael P.

    2015-01-01

    The Distributed Observer Network (DON) is a data presentation tool developed by the National Aeronautics and Space Administration (NASA) to distribute and publish simulation results. Leveraging the display capabilities inherent in modern gaming technology, DON places users in a fully navigable 3-D environment containing graphical models and allows the users to observe how those models evolve and interact over time in a given scenario. Each scenario is driven with data that has been generated by authoritative NASA simulation tools and exported in accordance with a published data interface specification. This decoupling of the data from the source tool enables DON to faithfully display a simulator's results and ensure that every simulation stakeholder will view the exact same information every time.

  2. Francis Bacon sob o olhar de Gilles Deleuze: a imagem como intensidade

    Directory of Open Access Journals (Sweden)

    Osvaldo Fontes Filho

    2007-12-01

    Full Text Available O ensaio de Gilles Deleuze La logique de la sensation é texto que se detém principalmente na prática e na eficácia da imagem. A pintura de Francis Bacon é ali tomada como paradigma de modernidade ao investir contra os clichês expressivos e ao produzir imagem junto à brutalidade dos fatos, como um contra-efeito do narrativo. Em uma obra que conjura todo modelo a representar, toda história a contar, “alguma coisa se passa”, explica Deleuze, “que define o funcionamento da pintura”. Algo se passa, tem lugar: o acontecimento de uma catástrofe e de uma histeria no ato de pintura que acomete a Figura de modo a transmitir uma potencial violência de reação e de expressão. O “Bacon” de Deleuze apresenta a realidade vivida em uma nova e não-convencional ordem de sensação. Neste artigo, são comentados os modos como o filósofo interpreta os atos físicos da pintura de Bacon — marcas aleatórias, varredura da massa pictural, escansão das superfícies —, procedimentos que introduzem no mundo visual da figuração a variedade caótica dos fatos e sentidos. Mostra-se como as faces e as figuras contorcidas, distorcidas, escorchadas de Bacon recebem uma voz conceitual complementar no texto de Deleuze. Consequentemente, focaliza-se a disposição de alguns conceitos do filósofo: diagrama, Figura, diferença, espaço háptico. Locados no espaço afetivo ou na “lógica da sensação” da pintura baconiana, esses conceitos atribuem legitimidade ao entrelaçamento e à co-implicação entre arte e filosofia. Uma última observação dá conta do fato de a prática da imagem em Bacon, apresentada por Deleuze no palco de uma modernidade particularmente solapada por um “dilúvio anestésico de imagens reprimindo a possibilidade de pensar”, evidenciar para o filósofo os rumos necessariamente sinuosos, “reptilíneos”, do pensamento moderno. Tanto o conceito como a forma criam por catástrofe, por conflagração, por varia

  3. Francis full-load surge mechanism identified by unsteady 2-phase CFD

    Energy Technology Data Exchange (ETDEWEB)

    Doerfler, P K; Keller, M; Braun, O, E-mail: peter.doerfler@andritz.co [R and D Department, Andritz Hydro Ltd., Zurich (Switzerland)

    2010-08-15

    Francis turbines may produce spontaneous pulsations of pressure and output power when operating at very high discharge. In such cases there is a cavitating central vortex in the draft tube with variable cavity volume V{sub c}. Until today, researchers agree that the main destabilizing agent is the so-called mass flow gain factor, defined as the derivative of cavity volume by the local discharge. Recent studies about 1D high-load stability analysis assumed that the mass-flow gain factor obtained from steady-state vortex data acts on the transient discharge downstream of the cavity. There are however good reasons to question this assumption. Most strikingly, the direct cause of the mass flow gain effect is the increase of swirl produced at the runner exit and hence upstream, not downstream of the cavity. To enhance the reliability of full-load stability predictions, the authors directly investigated the vortex dynamics. The development of the transient cavitating flow in the draft tube was simulated by means of unsteady 2-phase CFD. CFD work started with 1-phase calculations as presented by other authors. This was then extended to a more realistic 2-phase calculation. To contain the computing time within acceptable limits, given the very fine mesh and short time step required, the simulation domain was restricted to the draft tube and, at the same time, the problem was reduced to a basically 2-dimensional rotationally symmetric case. The response of the cavitating draft tube flow to a time-dependent inflow and time-dependent pressure at the draft tube exit was simulated. The results were input to a statistical identification procedure to check possible 1D transient models and find representative parameter values in the sense of a best fit between 1D model and CFD result. As we had suspected, the conventional vortex model with mass flow gain controlled by downstream discharge is not compatible with direct simulation and needs to be modified. The CFD results correspond

  4. THE DESIRE FOR RECOGNITION IN THE CONTEXT OF FRANCIS FUKUYAMA’S UNIVERSAL HISTORY

    Directory of Open Access Journals (Sweden)

    T. V. Danylova

    2016-12-01

    Full Text Available Introduction. Francis Fukuyama in his famous book “The End of History and the Last Man” assumes that human history should be considered as the battle of ideologies that reaches its goal in the universalization of Western liberal democracy. Author’s ideas have gained many supporters. At the same time, they were subjected to severe criticism that reflected the important trends of political life and ideological preferences. Leaving aside the criticism based on geopolitical and civilizational confrontation and confusion which confronts Fukuyama’s theory, it should be stated that anthropological aspect of Fukuyama’s theory has vastly evaded philosophical comprehension. Purpose. This article attempts to test Fukuyama’s theory through the lens of philosophical anthropology and analyze human desire for recognition in the context of Fukuyama’s World History. Methodology. The analysis is focused on human desire for recognition as a significant dimension of human nature. The author has used hermeneutical methodology and anthropological integrative approach. Theoretical basis and results. Fukuyama is not satisfied by merely economic interpretation of history emphasizing that human is not simply an economic animal. Economic development fails to explain why people advocate the principles of liberal democracy. The author goes back to Hegel’s non-materialistic view of history based on the struggle for recognition. According to Fukuyama, this deeply rooted human desire for recognition is the great motor of history and cause of tyranny, conflicts, and wars. But at the same time, it also acts as a psychological foundation of many virtues – the spirit of citizenship, courage, and justice. Throughout history, this desire for recognition was not satisfied. Only modern liberal democracy provides universal recognition of all humans ensuring and protecting their rights. Originality. Fukuyama’s concept is important and interesting because it draws

  5. Numerical investigation of a high head Francis turbine under steady operating conditions using foam-extend

    International Nuclear Information System (INIS)

    Lenarcic, M; Eichhorn, M; Schoder, S J; Bauer, Ch

    2015-01-01

    In this work the incompressible turbulent flow in a high head Francis turbine under steady operating conditions is investigated using the open source CFD software package FOAM-extend- 3.1. By varying computational domains (cyclic model, full model), coupling methods between stationary and rotating frames (mixing-plane, frozen-rotor) and turbulence models (kω-SST, κε), numerical flow simulations are performed at the best efficiency point as well as at operating points in part load and high load. The discretization is adjusted according the y + -criterion with y + mean > 30. A grid independence study quantifies the discretization error and the corresponding computational costs for the appropriate simulations, reaching a GCI < 1% for the chosen grid. Specific quantities such as efficiency, head, runner shaft torque as well as static pressure and velocity components are computed and compared with experimental data and commercial code. Focusing on the computed results of integral quantities and static pressures, the highest level of accuracy is obtained using FOAM in combination with the full model discretization, the mixing-plane coupling method and the κω-SST turbulence model. The corresponding relative deviations regarding the efficiency reach values of Δη rel ∼ 7% at part load, Δη rel ∼ 0.5% at best efficiency point and Δη rel ∼ 5.6% at high load. The computed static pressures deviate from the measurements by a maximum of Δp rel = 9.3% at part load, Δp rel = 4.3% at best efficiency point and Δp rel = 6.7% at high load. Commercial code in turn yields slightly better predictions for the velocity components in the draft tube cone, reaching a good accordance with the measurements at part load. Although FOAM also shows an adequate correspondence to the experimental data at part load, local effects near the runner hub are captured less accurate at best efficiency point and high load. Nevertheless, FOAM is a reasonable alternative to commercial code

  6. Science and Fiction. On Don Quijote’s Epistemological Skepticism

    Directory of Open Access Journals (Sweden)

    Félix Schmelzer

    2016-11-01

    Full Text Available The present work seeks to analyze the representation of scientific knowledge in Cervantes’ Quixote, focusing on various passages that underline the scientific expertise of don Quixote himself. It is shown that the novel contains a subtle critique of science, based on an epistemological skepticism with regard to the arbitrariness of our world concepts. The characterization of don Quixote as a man of science even permits deducting that he suffers from a ‘double mental damage’, caused by the lecture of both books of cavalry and science. Cervantes thus would consider science to be fiction, a very modern point of view.

  7. Pia Petersen sous le signe de don Quichotte

    Directory of Open Access Journals (Sweden)

    Esther Bautista Naranjo

    2013-04-01

    Full Text Available This interview has been motivated by the Cervantean intertextuality of Pia Petersen’s (a French-speaking Danish author last novel, Le Chien de don Quichotte (2012. Departing from the values that the writer attributes to Cervantes’ work, I try to establish a connection with a specific critical trend in order to test, later on, to which extent this approach is used by the author to create a series of characters placed under the sign of don Quixote. Finally, I evaluate her novel’s relation with contemporary reality.

  8. Fuel elements assembling for the DON project exponential experience

    International Nuclear Information System (INIS)

    Anca Abati, R. de

    1966-01-01

    It is described the fuel unit used in the DON exponential experience, the manufacturing installments and tools as well as the stages in the fabrication.These 74 elements contain each 19 cartridges loaded with synterized urania, uranium carbide and indium, gold, and manganese probes. They were arranged in calandria-like tubes and the process-tube. This last one containing a cooling liquid simulating the reactor organic. Besides being used in the DON reactor exponential experience they were used in critic essays by the substitution method in the French reactor AQUILON II. (Author) 6 refs

  9. Biologists Bridging Science and the Conservation Movement : The Rise of Nature Conservation and Nature Management in the Netherlands, 1850-1950

    NARCIS (Netherlands)

    van der Windt, Henny J.

    This paper investigates the importance and various roles of amateur naturalists and biologists in the conservation movement between 1850 and 1950, in particular in the Netherlands. It is concluded that biological sciences were important resources for Dutch nature conservation, although the extent of

  10. Environmental radiation effects. A need to question old paradigms and to enhance collaboration between radiation biologists and radiation ecologists

    International Nuclear Information System (INIS)

    Hinton, T.G.; Whicker, F.W.

    2003-01-01

    The radiological sciences are a real enigma- the maturity and depth of understanding concerning human dosimetry contrasts sharply with our shallow understanding about radiological effects to biota. The richness of the radiological sciences is apparent by looking at the refinements made to the fundamental unit used in human dosimetry. The radiological sciences have developed to where probabilistic risk factors can now be applied that predict specific deleterious effects to humans per unit dose. And yet, these same radiological sciences that have made such advances in human dosimetry, are primitive when effects to biota are concerned. There are no specialized units, no agreed upon weighting factors, no factors that account for distributions within an organism's body, and certainly no risk factors. There are no internationally agreed upon criteria or policies that explicitly address protection of the environment from ionizing radiation. There is not even agreement as to what endpoint should be measured to quantify an environmental effect. The bold aspect of the ICRP framework is the inclusion of sub-lethal effects (reduced reproductive success, scorable DNA damage) as endpoints. A major research consortium funded by the European Union, is also recommending that cytogenetic damage be used as an effect endpoint. The inclusion of sub-lethal endpoints begs for a linkage between molecular effects and those observed in individuals and populations. To do so, will require a strengthening of what has traditionally been separated disciplines of radiation biology and radiation ecology. The impacts of phenomena studied in the petri dishes of radiation biologists (such as genomic instability, adaptive response, and bystander effects) need to be explored and correlated to effects observed in whole organisms and populations, in collaboration with radiation ecologists. (M. Suetake)

  11. Processing the papal encyclical through perceptual filters: Pope Francis, identity-protective cognition, and climate change concern.

    Science.gov (United States)

    Landrum, Asheley R; Lull, Robert B; Akin, Heather; Hasell, Ariel; Jamieson, Kathleen Hall

    2017-09-01

    Previous research suggests that when individuals encounter new information, they interpret it through perceptual 'filters' of prior beliefs, relevant social identities, and messenger credibility. In short, evaluations are not based solely on message accuracy, but also on the extent to which the message and messenger are amenable to the values of one's social groups. Here, we use the release of Pope Francis's 2015 encyclical as the context for a natural experiment to examine the role of prior values in climate change cognition. Based on our analysis of panel data collected before and after the encyclical's release, we find that political ideology moderated views of papal credibility on climate change for those participants who were aware of the encyclical. We also find that, in some contexts, non-Catholics who were aware of the encyclical granted Pope Francis additional credibility compared to the non-Catholics who were unaware of it, yet Catholics granted the Pope high credibility regardless of encyclical awareness. Importantly, papal credibility mediated the conditional relationships between encyclical awareness and acceptance of the Pope's messages on climate change. We conclude by discussing how our results provide insight into cognitive processing of new information about controversial issues. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. Self-validated calculation of characteristics of a Francis turbine and the mechanism of the S-shape operational instability

    International Nuclear Information System (INIS)

    Zhang, Z; Titzschkau, M

    2012-01-01

    A calculation method has been presented to accurately estimate the characteristics of a Francis turbine. Both the shock loss at the impeller inlet and the swirling flow loss at the Impeller exit have been confirmed to dominantly influence the turbine characteristics and particularly the hydraulic efficiency. Both together totally govern the through flow of water through the impeller being at the rest. Calculations have been performed for the flow rate, the shaft torque and the hydraulic efficiency and compared with the available measurements on a model turbine. Excellent agreements have been achieved. Some other interesting properties of the turbine characteristics could also be derived from the calculations and verified by experiments. For this reason and because of not using any unreliable assumptions the calculation method has been confirmed to be self-validated. The operational instability in the upper range of the rotational speed, known as the S-shape instability, is ascribed to the total flow separation and stagnation at the impeller inlet. In that range of the rotational speed, the operation of the Francis turbine oscillates between pump and turbine mode.

  13. On Both Sides of the Atlantic: Re-Visioning Don Juan and Don Quixote in Modern Literature and Film

    OpenAIRE

    Perez, Karen Patricia

    2013-01-01

    The study analyzes contemporary literature and film based on two of the most universal characters in Spanish literature, Don Juan and Don Quixote, in both Spain and Hispanic America. Although both characters have undergone re-visioning from work to work through the centuries, it is the aim of this work to present the most salient characteristics of both archetypes in modern times only. The focus of this study is on works by well-known writers from Hispanic America and contemporary writers in ...

  14. Fallugia paradoxa (D. Don) Endl. ex Torr.: Apache-plume

    Science.gov (United States)

    Susan E. Meyer

    2008-01-01

    The genus Fallugia contains a single species - Apache-plume, F. paradoxa (D. Don) Endl. ex Torr. - found throughout the southwestern United States and northern Mexico. It occurs mostly on coarse soils on benches and especially along washes and canyons in both warm and cool desert shrub communities and up into the pinyon-juniper vegetation type. It is a sprawling, much-...

  15. IDEA: An Interdisciplinary Unit Comparing "Don Quixote" to "Hamlet."

    Science.gov (United States)

    Harris, Mary J. G.

    2001-01-01

    Describes an idea for teaching language through content-based instruction in which a high school Spanish class studying a shortened abridged version of Cervantes'"Don Quixote" and an English class reading Shakespeare's "Hamlet," did a simple comparative analysis of the two texts. (Author/VWL)

  16. Why Don't All Professors Use Computers?

    Science.gov (United States)

    Drew, David Eli

    1989-01-01

    Discusses the adoption of computer technology at universities and examines reasons why some professors don't use computers. Topics discussed include computer applications, including artificial intelligence, social science research, statistical analysis, and cooperative research; appropriateness of the technology for the task; the Computer Aptitude…

  17. "Don Kihotõ" nazõvajut lutshshih / Boris Tuch

    Index Scriptorium Estoniae

    Tuch, Boris, 1946-

    2003-01-01

    Lõppenud festivali FIPRESCI auhinna sai türgi film "Kauge" ("Uzak") : režissöör Nuri Bilge Ceylan. Rahvusvaheline filmiklubide föderatsioon (FICC) andis oma auhinna Don Quijote Andrei Zvjagintsevi filmile "Tagasitulek" ("Vozvrashtshenije") ja eriauhinna hiinlase Chen Kaige filmile "Üheskoos" ("Han ni zai ylki")

  18. Experiments in rooting bishop pine (Pinus muricata D. Don) cuttings

    Science.gov (United States)

    Constance I. Millar

    1987-01-01

    Presented here are results of rooting studies using hedges established from juvenile seedlings of "blue" and "green" foliaged bishop pine (Pinus muricata D. Don) from Mendocino and Sonoma Counties, California. Rootability, averaged over all clones and all setting dates, was 88%. The average time for 50% of the...

  19. 77 FR 64973 - Don W. Gilbert Hydro Power, LLC; Notice of Application Accepted for Filing With the Commission...

    Science.gov (United States)

    2012-10-24

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 14367-001] Don W. Gilbert...: Original Minor License. b. Project No.: 14367-001. c. Date filed: May 30, 2012. d. Applicant: Don W...(a)-825(r). (2006). h. Applicant Contact: Don W. Gilbert and DeAnn G. Somonich, Don W. Gilbert Hydro...

  20. Rotor optimization of a Francis type hydraulic turbine through the computer flow analysis (CFD); Optimizacion del rodete de una turbina hidraulica tipo Francis a traves del analisis computacional del flujo (CFD)

    Energy Technology Data Exchange (ETDEWEB)

    Rosado Tamariz, Erick

    2007-06-15

    In the analysis of fluid behavior through hydraulic turbines, two basic methodologies for flow analysis and optimization processes in turbines are used, which are: a) modeled of flow through the entire turbine (joint), or modeled one of each component separately, obtaining satisfactory results by both methodologies. The analysis of computational fluids dynamics (CFD) to geometries improved by means of finite volume method (FVM) with their corresponding initials and boundary conditions is made, to solve a system differential equations of second order that correspond to the flow around the dominion of runner blades; considering nonviscous flow and the implementation of the two equations models for the solution of the equations that govern the turbulent flow. Also, used parameterization techniques based in a parametric geometry an objective function and the diminution of cavitation. This work presents the optimization of a runner from a Francis hydro turbine for a 75 MW considering three different load conditions (75%, 85% and 100%) through CFD as a part of the hydraulic analysis for modernization of the actual condition of a power generation unit. Francis runner optimization is made, through a previous analysis of CFD by means of the FVM, considering the viscous effects of the fluid and the model of turbulence developed by Sparlart and Allmaras; modeling the wicket and runner separately. Later the generation of a parametric model of the runner is made and the simulation for the generation of data base is formed. Finally an objective function is considered to develop the optimal geometry of the runner blades. The results are presented in a graphic form in such a way, that it shows the distributions of pressure and speed around the blades runner, the geometrical and performance (efficiency and power) comparison between original and optimized model. [Spanish] En el analisis del comportamiento del fluido a traves de turbinas hidraulicas, se emplean dos metodologias

  1. Tod in den Anden. Ein Brief Francis Halls an Humboldt 1831 und seine historischen und politischen Hintergründe

    Directory of Open Access Journals (Sweden)

    Thomas Schmuck

    2013-12-01

    Full Text Available Zusammenfassung Der Forschungsreisende Francis Hall kam als Soldat nach Südamerika und betätigte sich hier auch als Pflanzensammler, Reiseschriftsteller und Bergsteiger. Er war Freund und Briefpartner Jeremy Benthams und versuchte gemeinsam mit Jean-Baptiste Boussingault den Chimborazo zu besteigen. Der liberale Journalist wurde 1833 in bürgerkriegsähnlichen Unruhen in Ecuador ermordet. Der einzige Brief Halls an Humboldt, in dem er diesen für die Naturerschließung des Landes zu gewinnen versucht, eine Sammlung andiner Pflanzen übersendet und seine Einschätzung zur politischen Lage und Zukunft Südamerikas kundtut, wird hier veröffentlicht und kommentiert. Abstract The British explorer Francis Hall was active in South-America as a soldier, a collector of plants, a writer of travelogues and a mountaineer. Together with Jean-Baptiste Boussingault he failed in ascending the Chimborazo. Friend and correspondent of Jeremy Bentham and also liberal journalist, Hall was killed during riots in Ecuador in 1833. In one single letter addressed to Humboldt, which is presented here, Hall tries to awaken interest for Ecuador, develops his views on the political future of South America and sends a collection of plants from the Andes. Resumen El explorador británico Francis Hall llegó a América del Sur como soldado y allí también se dedicó a la colección de plantas, a escribir sobre viajes y a hacer alpinismo. Intentó subir al Chimborazo con Jean-Baptiste Boussingault. El periodista liberal, amigo de Jeremy Bentham con el que también mantenía correspondencia, fue asesinado en los disturbios de 1833 en Ecuador. En la única carta de Hall a Humboldt, que está publicada y comentada aquí, Hall intenta despertar el interés de Humboldt por la naturaleza del país enviando una colección de plantas andinas y dando su opinión sobre la situación política y el futuro de América del Sur. (Traducción: Christine Lebas

  2. Francis Bacon czyli Diego Velázquez na fotelu dentystycznym - malarskie i inne cytaty jako "dodatek" do rozpraszającego się życia

    NARCIS (Netherlands)

    van Nieukerken, A.

    2014-01-01

    "Francis Bacon or Diego Velázquez in a dentist’s chair" - pictorial and other kinds of quotations as an addition to a disintegrating life The mature poetry of Tadeusz Różewicz seems to be at odds with both modernist and postmodern literary tenets. It undeniably makes abundant use of intertextuality

  3. Dialoguing from a Fixed Point: How Aristotle and Pope Francis Illuminate the Promise--and Limits--of Inclusion in Catholic Higher Education

    Science.gov (United States)

    Petrusek, Matthew Richard

    2017-01-01

    This article examines the meaning of the word "inclusion" as it relates to Catholic identity in higher education. Noting the widespread presence of this value in the mission statements of Catholic colleges, the article draws on insights from Aristotelian logic and Pope Francis's theology of encounter to argue that inclusion can only be…

  4. If Auditors Are Like Belgian Beers, Which Style Would You Prefer? : Discussion of “Auditor Style and Financial Statement Comparability” by Francis, Pinnuck, and Watanabe .

    NARCIS (Netherlands)

    Bruynseels, L.M.L.; Brenk, van H.M.

    2016-01-01

    Recent research by Francis, Pinnuck, and Watanabe (2014) has shown that financial reporting outcomes are influenced by the audit firm’s unique audit style. They argue that audit firm styles are driven by their “unique set of internal working rules that guide the auditor’s application of accounting

  5. St. Francis Rain Garden Water Quality Sampling Interim Data Report; Total Nitrogen, Total Phosphorus, Sediments or Solids, and E. Coli for the period April to June, 2014

    Science.gov (United States)

    This interim data reported is being provided per request to the Metropolitan Sewer District (MSD) to provide summary statistics on a limited set of water quality parameters as measured at the St. Francis Rain Garden site in the Lick Run Valley as it pertains to MSD's Project Grou...

  6. The Red-Attractiveness Effect, Applying the Ioannidis and Trikalinos (2007b) Test, and the Broader Scientific Context: A Reply to Francis (2013)

    Science.gov (United States)

    Elliot, Andrew J.; Maier, Markus A.

    2013-01-01

    Francis (2013) tested for and found evidence of publication bias in 1 of the 3 focal relations examined in Elliot et al. (2010), that between red and attractiveness. He then called into question the research as a whole and the field of experimental psychology more generally. Our reply has 3 foci. First, we attend to the bottom line regarding the…

  7. The Battle between the Biometricians and the Mendelians: How Sir Francis Galton's Work Caused His Disciples to Reach Conflicting Conclusions about the Hereditary Mechanism

    Science.gov (United States)

    Gillham, Nicholas W.

    2015-01-01

    Francis Galton, Charles Darwin's cousin, had wide and varied interests. They ranged from exploration and travel writing to fingerprinting and the weather. After reading Darwin's "On the Origin of Species," Galton reached the conclusion that it should be possible to improve the human stock through selective breeding, as was the…

  8. Renaissance Epyllions: A Comparative Reading of Christopher Marlowe's "Hero and Leander," Thomas Lodge's "Scylla's Metamorphosis" and Francis Beaumont's "Salmacis and Hermaphroditus"

    Science.gov (United States)

    Mahmoudi, Yazdan

    2016-01-01

    The present paper is supposed to compare and contrast three of these masterpieces written the Renaissance period. The epyllions under study are Christopher Marlowe's "Hero and Leander," Thomas Lodge's "Scylla's Metamorphosis" and Francis Beaumont's "Salmacis and Hermaphroditus." Bush believes that "the influence…

  9. Il De uno alla luce dell’Exemplum tractatus de iustitia universali, sive de fontibus iuris di Francis Bacon

    Directory of Open Access Journals (Sweden)

    Romana Bassi

    2016-11-01

    Full Text Available [Reading “De uno” in light of Francis Bacon’s “Exemplum tractatus de iustitia universali, sive de fontibus iuris”]. Although Vico was admittedly disappointed by Bacon’s Exemplum tractatus, a parallel reading of this text and De uno can provide insights as to how Vico ended up having to confront a series of issues: how does the universal law project itself into history? Where does the law stem from? Is there a link between law, occasion, and utility? What are the sources and the scope of authority? How does violence affect the law? What role for religion and piety? How to devise a philology for the laws and ancient fables? Bacon’s scattered aphorisms offer glimpses into problems which find a solution in the all-encompassing order of De uno.

  10. Francis-99 turbine numerical flow simulation of steady state operation using RANS and RANS/LES turbulence model

    Science.gov (United States)

    Minakov, A.; Platonov, D.; Sentyabov, A.; Gavrilov, A.

    2017-01-01

    We performed numerical simulation of flow in a laboratory model of a Francis hydroturbine at three regimes, using two eddy-viscosity- (EVM) and a Reynolds stress (RSM) RANS models (realizable k-ɛ, k-ω SST, LRR) and detached-eddy-simulations (DES), as well as large-eddy simulations (LES). Comparison of calculation results with the experimental data was carried out. Unlike the linear EVMs, the RSM, DES, and LES reproduced well the mean velocity components, and pressure pulsations in the diffusor draft tube. Despite relatively coarse meshes and insufficient resolution of the near-wall region, LES, DES also reproduced well the intrinsic flow unsteadiness and the dominant flow structures and the associated pressure pulsations in the draft tube.

  11. Francis Pomponi, Vendetta, justice et politique en Corse. « L’affaire Viterbi » (1789-1821

    Directory of Open Access Journals (Sweden)

    Jean-Claude Farcy

    2010-08-01

    Full Text Available Causes célèbres, crimes et criminels sortant de l’ordinaire ont toujours passionné l’opinion et donné naissance à une littérature à succès, revenant périodiquement sur les mêmes affaires judiciaires. Les historiens de la criminalité et de la justice ont, plus récemment, emprunté cette voie et revisité nombre de ces affaires en les replaçant, avec plus ou moins de succès, dans le contexte de leur époque. L’ouvrage de Francis Pomponi s’inscrit dans cette perspective, celle d’une étude de cas, d...

  12. Charged Particles are Prevented from Going Faster than the Speed of Light by Light Itself: A Biophysical Cell Biologist's Contribution to Physics

    International Nuclear Information System (INIS)

    Wayne, R.

    2010-01-01

    Investigations of living organisms have led biologists and physicians to introduce fundamental concepts, including Brownian motion, the First Law of Thermodynamics, Poiseuille's Law of fluid flow, and Fick's Law of diffusion into physics. Given the prominence of viscous forces within and around cells and the experience of identifying and quantifying such resistive forces, biophysical cell biologists have an unique perspective in discovering the viscous forces that cause moving particles to respond to an applied force in a nonlinear manner. Using my experience as a biophysical cell biologist, I show that in any space consisting of a photon gas with a temperature above absolute zero, Doppler-shifted photons exert a velocity-dependent viscous force on moving charged particles. This viscous force prevents charged particles from exceeding the speed of light. Consequently, light itself prevents charged particles from moving faster than the speed of light. This interpretation provides a testable alternative to the interpretation provided by the Special Theory of Relativity, which contends that particles are prevented from exceeding the speed of light as a result of the relativity of time. (author)

  13. LDV survey of cavitation and resonance effect on the precessing vortex rope dynamics in the draft tube of Francis turbines

    Science.gov (United States)

    Favrel, A.; Müller, A.; Landry, C.; Yamamoto, K.; Avellan, F.

    2016-11-01

    The large-scale penetration of the electrical grid by intermittent renewable energy sources requires a continuous operating range extension of hydropower plants. This causes the formation of unfavourable flow patterns in the draft tube of turbines and pump-turbines. At partial load operation, a precessing cavitation vortex rope is formed at the Francis turbine runner outlet, acting as an excitation source for the hydraulic system. In case of resonance, the resulting high-amplitude pressure pulsations can put at risk the stability of the machine and of the electrical grid to which it is connected. It is therefore crucial to understand and accurately simulate the underlying physical mechanisms in such conditions. However, the exact impact of cavitation and hydro-acoustic resonance on the flow velocity fluctuations in the draft tube remains to be established. The flow discharge pulsations expected to occur in the draft tube in resonance conditions have for instance never been verified experimentally. In this study, two-component Laser Doppler Velocimetry is used to investigate the axial and tangential velocity fluctuations at the runner outlet of a reduced scale physical model of a Francis turbine. The investigation is performed for a discharge equal to 64 % of the nominal value and three different pressure levels in the draft tube, including resonance and cavitation-free conditions. Based on the convective pressure fluctuations induced by the vortex precession, the periodical velocity fluctuations over one typical precession period are recovered by phase averaging. The impact of cavitation and hydro-acoustic resonance on both axial and tangential velocity fluctuations in terms of amplitude and phase shift is highlighted for the first time. It is shown that the occurrence of resonance does not have significant effects on the draft tube velocity fields, suggesting that the synchronous axial velocity fluctuations are surprisingly negligible compared to the velocity

  14. FRamework Assessing Notorious Contributing Influences for Error (FRANCIE): Perspective on Taxonomy Development to Support Error Reporting and Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Lon N. Haney; David I. Gertman

    2003-04-01

    Beginning in the 1980s a primary focus of human reliability analysis was estimation of human error probabilities. However, detailed qualitative modeling with comprehensive representation of contextual variables often was lacking. This was likely due to the lack of comprehensive error and performance shaping factor taxonomies, and the limited data available on observed error rates and their relationship to specific contextual variables. In the mid 90s Boeing, America West Airlines, NASA Ames Research Center and INEEL partnered in a NASA sponsored Advanced Concepts grant to: assess the state of the art in human error analysis, identify future needs for human error analysis, and develop an approach addressing these needs. Identified needs included the need for a method to identify and prioritize task and contextual characteristics affecting human reliability. Other needs identified included developing comprehensive taxonomies to support detailed qualitative modeling and to structure meaningful data collection efforts across domains. A result was the development of the FRamework Assessing Notorious Contributing Influences for Error (FRANCIE) with a taxonomy for airline maintenance tasks. The assignment of performance shaping factors to generic errors by experts proved to be valuable to qualitative modeling. Performance shaping factors and error types from such detailed approaches can be used to structure error reporting schemes. In a recent NASA Advanced Human Support Technology grant FRANCIE was refined, and two new taxonomies for use on space missions were developed. The development, sharing, and use of error taxonomies, and the refinement of approaches for increased fidelity of qualitative modeling is offered as a means to help direct useful data collection strategies.

  15. Space and time reconstruction of the precessing vortex core in Francis turbine draft tube by 2D-PIV

    Science.gov (United States)

    Favrel, A.; Müller, A.; Landry, C.; Yamamoto, K.; Avellan, F.

    2016-11-01

    Francis turbines operating at part load conditions experience the development of a high swirling flow at the runner outlet, giving rise to the development of a cavitation precessing vortex rope in the draft tube. The latter acts as an excitation source for the hydro-mechanical system and may jeopardize the system stability if resonance conditions are met. Although many aspects of the part load issue have been widely studied in the past, the accurate stability analysis of hydro-power plants remains challenging. A better understanding of the vortex rope dynamics in a wide range of operating conditions is an important step towards the prediction and the transposition of the pressure fluctuations from reduced to prototype scale. For this purpose, an investigation of the flow velocity fields at the outlet of a Francis turbine reduced scale physical model operating at part load conditions is performed by means of 2D-PIV in three different horizontal cross-sections of the draft tube cone. The measurements are performed in cavitation-free conditions for three values of discharge factor, comprised between 60% and 81% of the value at the Best Efficiency Point. The present article describes a detailed methodology to properly recover the evolution of the velocity fields during one precession cycle by means of phase averaging. The vortex circulation is computed and the vortex trajectory over one typical precession period is finally recovered for each operating point. It is notably shown that below a given value of the discharge factor, the vortex dynamics abruptly change and loose its periodicity and coherence.

  16. CDC Vital Signs–Blood Pressure Medicines Don’t Work If People Don’t Take Them

    Centers for Disease Control (CDC) Podcasts

    2016-09-13

    Blood pressure medicines don’t work if people don’t take them. Learn how health care systems can work with patients to make taking medicines easier.  Created: 9/13/2016 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 9/13/2016.

  17. Blood Pressure Medicines Don’t Work If People Don’t Take Them PSA (:60)

    Centers for Disease Control (CDC) Podcasts

    This 60 second public service announcement is based on the September 2016 CDC Vital Signs report. Blood pressure medicines don’t work if people don’t take them. Learn how health care systems can work with patients to make taking medicines easier.

  18. To the Spanish Young People: Don Quixote Dreyfussard

    Directory of Open Access Journals (Sweden)

    Virginia Ramírez Martín

    2013-12-01

    Full Text Available In 1898, Spanish press take up part of its pages with a relevant international issue: the Dreyfus affair. The case was widely covered by Spanish newspapers, in special by Don Quijote, a Madrilenian satiric press, whose Director promoted a campaign in favour of Zola collecting signatures in order to the French litterateur was aware that Spain was close to him. This initiative is completed with a call to Spanish young people who is illustrated with a quixotic caricature. Cervantine character personifies the idea of justice getting to transmit during the Spanish crisis at the end of the nineteenth century the image of the nobleman forged by Spanish stereotypical, like a crusader fighting for a noble cause, thus turning Don Quixote into another dreyfussard.

  19. Don Quixote an Celia: the desire to live other lives

    Directory of Open Access Journals (Sweden)

    María Jesús Fraga Fernández-Cuevas

    2012-12-01

    Full Text Available The present study explores the parallelisms between Don Quixote and Elena Fortun’s novels Celia. First, it enumerates the various activities that prove the author’s interest in Cervantes and his work, as well as the possible intervention of her mentor, Maria Martinez Sierra, in the genesis of the child’s character. Both novels, of dialogical nature, share an episodic structure articulated by a weak storyline. Its protagonists are animated by the desire to live the lives of the characters of their favorite readings. They confuse fantasy and reality causing situations whose results are almost always adverse. If Don Quixote dies back to the reason, so will Celia, the girl, with her entry into adulthood by resigning her fantasies, which will be taken up by new generations of children.

  20. Don Carlos: Variations of Tragic from Schiller to Verdi

    Directory of Open Access Journals (Sweden)

    Fabio Vittorini

    2017-11-01

    Full Text Available In 1867 Giuseppe Verdi makes a grand opéra out of the dramatic poem Don Carlos, Infant von Spanien (1787 by Friedrich von Schiller. The workshop of Don Carlos lasts twenty years, from 1866 to 1886, when Verdi (reopens and closes several other workshops (Simon Boccanegra, La forza del destino, Aida, Requiem, Otello, creating a porous work in progress, whose analysis keeps giving us surprises. The libretto by Joseph Méry et Camille Du Locle, under the supervision of the composer, is a palimpsest where, under the official text referable to the common historical nucleus and its best known literary versions, some hidden or deleted heterogeneous texts appear, in a supranational, multilinguistic, intercultural and intertextual dimension, not always stirring along the road of a locatable derivation, of a voluntary imitation, but sometimes taking the shape of an unpredictable dissemination.

  1. Don Quijote in Nineteenth-Century English Theatre

    Directory of Open Access Journals (Sweden)

    J. A. Garrido Ardila

    2014-12-01

    Full Text Available This article brings to light a group of Cervantine English literary works hitherto unknown to present-day Cervantes studies: seven theatrical adaptations of Don Quixote (two anonymous ones in addition to those by Charles Dibdin, Joseph Moser, G. A. Macfarren, C. A. Maltby and P. Milton, a comedy with a Quixotic title (by George Dance, and five Quixotic fictions (two anonymous, in addition to those by Lily Spender, Maurice Hewlett and A. T. Quiller-Couch. Three of these plays, had been noted by Leopoldo Rius in 1899 (Moser, Macfarren, Maltby; the other four are presented for the first time here. In order to chart a fuller and more complete history of Don Quixote on the English stage, this article provides relevant information on those seven plays. An examination of these works reinforces the previous theses that underscore the essentially comical nature of Quixotic plays in nineteenth-century England, a fact of relevance in the study of the English reception of Don Quixote in the course of that century.

  2. Mineral characterisation of Don Pao rare earth deposit in Vietnam

    International Nuclear Information System (INIS)

    XuanBen, T.

    1998-01-01

    Full text: The Don Pao Rare Earth Deposit was discovered in 1959 in Phon Tho district, about 450km North-West of Hanoi capital. Geological work was conducted between 1959-95, resulting in 60 ore bodies of various sizes being identified. The ore bodies are irregularly shaped nests, lenses and veins hosted in the shear zone, at the margin of a Paeleogene aged syenite massif. The mineral composition of Don Pao Deposit is very complex, consisting of more than 50 minerals. Among them, basnaesite, parisite, fluorite and barite are the main constituent minerals of the ore. All the minerals were identified by the modern methods of mineralogical studies. Based on the constituent mineral ratios, four ore types have been distinguished in the deposit: 1. Rare earth ore containing over 5 percent of RE 2 O 3 . 2. Rare Earth-Barite ore containing 0.5 to 30 percent of RE 2 O 3 . 3. Rare Earth-Barite-Fluorite ore containing 1 to 5 percent of RE 2 O 3 . 4. Rare Earth bearing Fluorite ore containing 1 to 5 percent of RE 2 O 3 . According to the benefication test, the ores in Don Pao can be enriched to a concentrate of 60 percent of RE 2 O 3 with a recover of 75 percent

  3. Lesbian, Gay, Bisexual, and Transgender (LGBT) Service Members: Life After Don't Ask, Don't Tell.

    Science.gov (United States)

    Goldbach, Jeremy T; Castro, Carl Andrew

    2016-06-01

    Lesbian, gay, and bisexual service members can serve openly in the military with the repeal of the Don't Ask, Don't Tell policy. The fate of transgender service members remains uncertain as the policy preventing them from serving in the military remains under review. The health care needs of these populations remain for the most part unknown, with total acceptance and integration in the military yet to be achieved. In this paper, we review the literature on the health care needs of lesbian, gay, bisexual, and transgender (LGBT) service members, relying heavily on what is known about LGBT civilian and veteran populations. Significant research gaps about the health care needs of LGBT service members are identified, along with recommendations for closing those gaps. In addition, recommendations for improving LGBT acceptance and integration within the military are provided.

  4. The myth of the warrior: martial masculinity and the end of Don't Ask, Don't Tell.

    Science.gov (United States)

    Allsep, L Michael

    2013-01-01

    The image of the male warrior still dominates military culture, to the exclusion of women and homosexuals. Complicating the picture is a technological revolution that promises to widen the current gap between the myth and reality of the modern warrior even further. Nonetheless, despite long arguing that homosexuals were a direct threat to military culture and effectiveness, the Pentagon has largely treated the end of Don't Ask, Don't Tell as a policy matter. The difficulties still experienced by women in the armed services 40 years after they were first incorporated in significant numbers indicates that this response will be insufficient to address the deeper cultural issues. Gender issues implicate deeply held beliefs and values that persist even in the face of years of official admonishment and denial. Unless the military begins to transparently bridge the gap between the myth and reality of the modern warrior, military service without discrimination based on sexual orientation will remain an unachieved goal.

  5. Don Quixote Pond: A Small Scale Model of Weathering and Salt Accumulation

    Science.gov (United States)

    Englert, P.; Bishop, J. L.; Patel, S. N.; Gibson, E. K.; Koeberl, C.

    2015-01-01

    The formation of Don Quixote Pond in the North Fork of Wright Valley, Antarctica, is a model for unique terrestrial calcium, chlorine, and sulfate weathering, accumulation, and distribution processes. The formation of Don Quixote Pond by simple shallow and deep groundwater contrasts more complex models for Don Juan Pond in the South Fork of Wright Valley. Our study intends to understand the formation of Don Quixote Pond as unique terrestrial processes and as a model for Ca, C1, and S weathering and distribution on Mars.

  6. Don Quichotte, un don quichotte ? Déprogrammation d’un stéréotype

    Directory of Open Access Journals (Sweden)

    Marta Cuenca-Godbert

    2009-12-01

    Full Text Available En réaction à la publication de la suite apocryphe de Don Quichotte de la Manche, Cervantès utilise dans sa seconde partie les ressorts narratifs de la stéréotypie littéraire pour montrer à quel point son personnage diffère de ce qu'en a fait Alonso Fernández de Avellaneda, continuateur peu respectueux de sa personne et de son personnage. Le refus de voir en don Quichotte un simple stéréotype du chevalier errant chimérique est particulièrement manifeste dans la série d'aventures se déroulant au château des ducs, où don Quichotte, par sa renommée littéraire littéralement reconnue, est traité en chevalier par des personnages manipulateurs de situations, qui visent à produire chez lui des réactions programmées pour s’en amuser. Il apparaît alors que le simple agrégat d'ingrédients propres au stéréotype littéraire chevaleresque finit par ne pas produire l'issue escomptée.En la Segunda parte del Quijote, Cervantes reacciona ante la publicación de la de Alonso Fernández de Avellaneda, continuador poco respetuoso con la persona del autor primigenio y su personaje. Recurriendo a los procedimientos narrativos de la estereotipia literaria deja bien claro qué diferente resulta ser el personaje original respecto al del continuador. La negativa de ver a don Quijote como un mero estereotipo del caballero andante loco se pone particularmente de manifiesto en la serie de aventuras que transcurren en el palacio de los duques. Allí, los personajes reconocen literalmente la fama literaria de don Quijote. Generan, desde situaciones ficticias, tipos de tratamiento que se dispensarían a un verdadero caballero andante. Como resultado, se desencadena una serie de reacciones programadas con las que pretenden divertirse. Sin embargo, queda claro que la mera acumulación de ingredientes propios del estereotipo literario caballeresco no produce el resultado esperado.

  7. Road Bridges and Culverts, MDTA Culverts, Culverts on John F. Kennedy Highway (I95), Baltimore Harbor Tunnel Throughway, Francis Scott Key Bridge, Bay bridge, Nice Bridge, Published in 2010, 1:1200 (1in=100ft) scale, Maryland Transportation Authority.

    Data.gov (United States)

    NSGIC State | GIS Inventory — Road Bridges and Culverts dataset current as of 2010. MDTA Culverts, Culverts on John F. Kennedy Highway (I95), Baltimore Harbor Tunnel Throughway, Francis Scott Key...

  8. THE SONATA FOR CLARINET AND PIANO BY FRANCIS POULENC FROM THE POINT OF VIEW OF THE GENRE EVOLUTION OF THE 20th CENTURY SONATA

    Directory of Open Access Journals (Sweden)

    ROJNOVEANU ANGELA

    2015-09-01

    Full Text Available The article focuses on the analysis of the Sonata for clarinet and piano by Francis Poulenc that still presents great interest nowadays. This is a masterpiece of twenty century music – an original composition considered from the point of view of its stylistic structure in the context of the experiments carried out in the composition techniques of last century. The author ap­proaches problems of opus themes and architectonics as well as some aspects of musical language.

  9. A Novel Source of DOC and DON to Watershed Soils

    Science.gov (United States)

    Aitkenhead-Peterson, J. A.

    2017-12-01

    A source of dissolved organic carbon (DOC) and nitrogen (DON) to soils and groundwater is that emanating from decomposing mammals. Although there is an increase in human donor facilities (body farms) in the USA and in mass mortality events (MME) worldwide, this injection of DOC and DON into watershed soils has received little attention. Studies at two human donor facilities in Texas, USA have revealed that the purge fluid associated with decomposition is extremely high in DOC and DON and migrates down the soil profile. Two studies were carried out 1) The southeast Texas Applied Forensic Science (STAFS) facility on an Alfisol with a saturated hydraulic conductivity of 331 mm hr-1 and 83% sand and 2) the Forensic Anthropology Research Facility (FARF) on Mollisols with a saturated hydraulic conductivity of 3.6-9.7 mm hr-1 and 28-33% sand. The numbers of days since donors were laid in the environment ranged from 219-680 d at STAFS and 306-960 d at FACTS. Purge can occur between 5 and 30 d dependent on the time of year the body is placed and the resultant phenomenon is termed cadaver decomposition island (CDI). Soil cores were taken at 5 cm increments to a depth of 30 cm in the sandy soil and 15 cm in the clayey/rocky soil. In the sandy soils, DOC concentrations were significantly higher in all the CDI soils when compared to control soils at depths of 15, 20, 25 and 30 cm and ranged from 121.7 µg g-1 (30 cm) to 167.6 µg g-1 (15 cm) in control soils and 461.9 µg g-1 (30 cm) to 660.4 µg g-1 (15 cm) in CDI soils, representing a three- to four-fold increase in DOC relative to control soils. DON in all CDI soils was not significantly higher than control soils until 30 cm depth and ranged from 9.9-32.3 µg g-1 in CDI soils and 121.7 µg g-1 in control soil, representing a two- to seven-fold increase in DON relative to control soils. DOC concentrations in control soils at the FARF site at 15 cm ranged 215-365 µg g-1 while in the CDI soils DOC was higher (range: 270

  10. Compassionate care in radiography recruitment, education and training: A post-Francis Report review of the current literature and patient perspectives

    International Nuclear Information System (INIS)

    Bleiker, J.; Knapp, K.M.; Hopkins, S.; Johnston, G.

    2016-01-01

    Compassion is elemental in the care of a patient during their medical imaging (MI) procedure and is highly topical in the light of the Francis Report. The patient–practitioner interaction is an amalgam of context, communication and individual differences, and whilst compassion is a term in common parlance in the media, policy and radiographers' professional documents, its meaning and manifestation in radiography recruitment, education and practice are less clearly articulated. A review of the existing literature was undertaken, including a small scale study exploring patients' experiences in diagnostic medical imaging. Themes from the study included communication; competence; emotions; attitudes and relationships, but notably absent was any mention of compassion per se. Radiography research would benefit from further exploratory work into the nature of compassionate patient care in the unique context of the medical imaging encounter; offering an evidence-based contribution to radiography in the light of the Francis Report. - Highlights: • An increased focus on compassion was recommended in the Francis Report. • Best compassionate care is a requirement in radiographers' Code of Professional Conduct. • The meaning of compassionate patient care in radiography is not well understood. • Equally neither is the expression of compassion in radiography. • Research into compassion will contribute to evidence-based practice in radiography.

  11. Adrenalectomy for Cushing's syndrome: do's and don'ts.

    Science.gov (United States)

    Paduraru, D N; Nica, A; Carsote, M; Valea, A

    2016-01-01

    Aim. To present specific aspects of adrenalectomy for Cushing's syndrome (CS) by introducing well established aspects ("do's") and less known aspects ("don'ts"). Material and Method. This is a narrative review. Results. The "do's" for laparoscopic adrenalectomy (LA) are the following: it represents the "gold standard" for secretor and non-secretor adrenal tumors and the first line therapy for CS with an improvement of cardio-metabolic co-morbidities; the success rate depending on the adequate patients' selection and the surgeon's skills. The "don'ts" are large (>6-8 centimeters), locally invasive, malignant tumors requiring open adrenalectomy (OA). Robotic adrenalectomy is a new alternative for LA, with similar safety and conversion rate and lower pain drugs use. The "don'ts" are the following: lack of randomized controlled studies including oncologic outcome, different availability at surgical centers. Related to the sub-types of CS, the "do's" are the following: adrenal adenomas which are cured by LA, while adrenocortical carcinoma (ACC) requires adrenalectomy as first line therapy and adjuvant mitotane therapy; synchronous bilateral adrenalectomy (SBA) is useful for Cushing's disease (only cases refractory to pituitary targeted therapy), for ectopic Cushing's syndrome (cases with unknown or inoperable primary site), and for bilateral cortisol producing adenomas. The less established aspects are the following: criteria of skilled surgeon to approach ACC; the timing of surgery in subclinical CS; the need for adrenal vein catheterization (which is not available in many centers) to avoid unnecessary SBA. Conclusion. Adrenalectomy for CS is a dynamic domain; LA overstepped the former OA area. The future will improve the knowledge related to RA while the cutting edge is represented by a specific frame of intervention in SCS, children and pregnant women. Abbreviations: ACC = adrenocortical carcinoma, ACTH = Adrenocorticotropic Hormone, CD = Cushing's disease, CS

  12. La prolongation de la vie humaine selon Francis Bacon. Ou : quel Tithon voulons-nous être ?

    Directory of Open Access Journals (Sweden)

    Dominique Weber

    2011-07-01

    Full Text Available Afin de comprendre avec exactitude la manière dont Francis Bacon envisage la question de la prolongation de la vie humaine, il faut impérativement examiner l’assise théologique de la réflexion du philosophe à ce sujet. Il convient aussi de restituer l’intégration de cette réflexion dans les objectifs plus amples de la philosophie naturelle nouvelle. Enfin, il est nécessaire de comprendre les dimensions proprement morales de la question. Car la prolongation de la vie humaine n’est pas seulement, au sein de la philosophie naturelle nouvelle, un cas parmi d’autres des recherches qu’il faut désormais effectuer : en réalité, c’est elle qui lui donne et qui lui fixe son sens ; avec elle se joue l’effectivité de l’identité espérée entre science et puissance. Mais il faut encore préciser qu’il ne s’agit aucunement pour l’homme de vieillir pour vieillir : il s’agit pour lui de pouvoir vieillir bien. Les leçons que Bacon tire de la fable de Tithon sont ici véritablement décisives.

  13. An Intelligent Optimization Method for Vortex-Induced Vibration Reducing and Performance Improving in a Large Francis Turbine

    Directory of Open Access Journals (Sweden)

    Xuanlin Peng

    2017-11-01

    Full Text Available In this paper, a new methodology is proposed to reduce the vortex-induced vibration (VIV and improve the performance of the stay vane in a 200-MW Francis turbine. The process can be divided into two parts. Firstly, a diagnosis method for stay vane vibration based on field experiments and a finite element method (FEM is presented. It is found that the resonance between the Kármán vortex and the stay vane is the main cause for the undesired vibration. Then, we focus on establishing an intelligent optimization model of the stay vane’s trailing edge profile. To this end, an approach combining factorial experiments, extreme learning machine (ELM and particle swarm optimization (PSO is implemented. Three kinds of improved profiles of the stay vane are proposed and compared. Finally, the profile with a Donaldson trailing edge is adopted as the best solution for the stay vane, and verifications such as computational fluid dynamics (CFD simulations, structural analysis and fatigue analysis are performed to validate the optimized geometry.

  14. Nonlinear dynamic analysis and robust controller design for Francis hydraulic turbine regulating system with a straight-tube surge tank

    Science.gov (United States)

    Liang, Ji; Yuan, Xiaohui; Yuan, Yanbin; Chen, Zhihuan; Li, Yuanzheng

    2017-02-01

    The safety and stability of hydraulic turbine regulating system (HTRS) in hydropower plants become increasingly important since the rapid development and the broad application of hydro energy technology. In this paper, a novel mathematical model of Francis hydraulic turbine regulating system with a straight-tube surge tank based on a few state-space equations is introduced to study the dynamic behaviors of the HTRS system, where the existence of possible unstable oscillations of this model is studied extensively and presented in the forms of the bifurcation diagram, time waveform plot, phase trajectories, and power spectrum. To eliminate these undesirable behaviors, a specified fuzzy sliding mode controller is designed. In this hybrid controller, the sliding mode control law makes full use of the proposed model to guarantee the robust control in the presence of system uncertainties, while the fuzzy system is applied to approximate the proper gains of the switching control in sliding mode technique to reduce the chattering effect, and particle swarm optimization is developed to search the optimal gains of the controller. Numerical simulations are presented to verify the effectiveness of the designed controller, and the results show that the performances of the nonlinear HTRS system assisted with the proposed controller is much better than that with the commonly used optimal PID controller.

  15. Influence of upstream disturbance on the draft-tube flow of Francis turbine under part-load conditions

    Science.gov (United States)

    Chen, Ting; Zheng, Xianghao; Zhang, Yu-ning; Li, Shengcai

    2018-02-01

    Owing to the part-load operations for the enhancement of grid flexibility, the Francis turbine often suffers from severe low-frequency and large-amplitude hydraulic instability, which is mostly pertinent to the highly unsteady swirling vortex rope in the draft tube. The influence of disturbances in the upstream (e.g., large-scale vortex structures in the spiral casing) on the draft-tube vortex flow is not well understood yet. In the present paper, the influence of the upstream disturbances on the vortical flow in the draft tube is studied based on the vortex identification method and the analysis of several important parameters (e.g., the swirl number and the velocity profile). For a small guide vane opening (representing the part-load condition), the vortices triggered in the spiral casing propagate downstream and significantly affect the swirling vortex-rope precession in the draft tube, leading to the changes of the intensity and the processional frequency of the swirling vortex rope. When the guide vane opening approaches the optimum one (representing the full-load condition), the upstream disturbance becomes weaker and thus its influences on the downstream flow are very limited.

  16. Proper Orthogonal Decomposition of Pressure Fields in a Draft Tube Cone of the Francis (Tokke) Turbine Model

    International Nuclear Information System (INIS)

    Stefan, D; Rudolf, P

    2015-01-01

    The simulations of high head Francis turbine model (Tokke) are performed for three operating conditions - Part Load, Best Efficiency Point (BEP) and Full Load using software Ansys Fluent R15 and alternatively OpenFOAM 2.2.2. For both solvers the simulations employ Realizable k-e turbulence model. The unsteady pressure pulsations of pressure signal from two monitoring points situated in the draft tube cone and one behind the guide vanes are evaluated for all three operating conditions in order to compare frequencies and amplitudes with the experimental results. The computed velocity fields are compared with the experimental ones using LDA measurements in two locations situated in the draft tube cone. The proper orthogonal decomposition (POD) is applied on a longitudinal slice through the draft tube cone. The unsteady static pressure fields are decomposed and a spatio-temporal behavior of modes is correlated with amplitude-frequency results obtained from the pressure signal in monitoring points. The main application of POD is to describe which modes are related to an interaction between rotor (turbine runner) and stator (spiral casing and guide vanes) and cause dynamic flow behavior in the draft tube. The numerically computed efficiency is correlated with the experimental one in order to verify the simulation accuracy

  17. An Evaluation of a Phase-Lag Boundary Condition for Francis Hydroturbine Simulations Using a Pressure-Based Solver

    Science.gov (United States)

    Wouden, Alex; Cimbala, John; Lewis, Bryan

    2014-11-01

    While the periodic boundary condition is useful for handling rotational symmetry in many axisymmetric geometries, its application fails for analysis of rotor-stator interaction (RSI) in multi-stage turbomachinery flow. The inadequacy arises from the underlying geometry where the blade counts per row differ, since the blade counts are crafted to deter the destructive harmonic forces of synchronous blade passing. Therefore, to achieve the computational advantage of modeling a single blade passage per row while preserving the integrity of the RSI, a phase-lag boundary condition is adapted to OpenFOAM® software's incompressible pressure-based solver. The phase-lag construct is accomplished through restating the implicit periodic boundary condition as a constant boundary condition that is updated at each time step with phase-shifted data from the coupled cells adjacent to the boundary. Its effectiveness is demonstrated using a typical Francis hydroturbine modeled as single- and double-passages with phase-lag boundary conditions. The evaluation of the phase-lag condition is based on the correspondence of the overall computational performance and the calculated flow parameters of the phase-lag simulations with those of a baseline full-wheel simulation. Funded in part by DOE Award Number: DE-EE0002667.

  18. On the Flow Instabilities and Turbulent Kinetic Energy of Large-Scale Francis Hydroturbine Model at Low Flow Rate Conditions

    Directory of Open Access Journals (Sweden)

    Wen-Tao Su

    2014-07-01

    Full Text Available This paper is to make a better understanding of the flow instabilities and turbulent kinetic energy (TKE features in a large-scale Francis hydroturbine model. The flow instability with aspect of pressure oscillation and pressure-velocity correlation was investigated using large eddy simulation (LES method along with two-phase cavitation model. The numerical simulation procedures were validated by the existing experimental result, and further the TKE evolution was analyzed in a curvilinear coordinates. By monitoring the fluctuating pressure and velocities in the vanes’ wake region, the local pressure and velocity variations were proven to have a phase difference approaching π/2, with a reasonable cross-correlation coefficient. Also the simultaneous evolution of pressure fluctuations at the opposite locations possessed a clear phase difference of π, indicating the stresses variations on the runner induced by pressure oscillation were in an odd number of nodal diameter. Considering the TKE generation, the streamwise velocity component us′2 contributed the most to the TKE, and thus the normal stress production term and shear stress production term imparted more instability to the flow than other production terms.

  19. Les livres de recettes « francisés » au Mexique au XIXe siècle

    Directory of Open Access Journals (Sweden)

    Sarah Bak-Geller Corona

    2008-05-01

    Full Text Available L’apparition des premiers livres de cuisine au Mexique - publiés par des maisons d’édition françaises spécialisées en ouvrages en espagnol - marque le début de l’histoire de la cuisine mexicaine. Cet événement s’inscrit par ailleurs dans une histoire plus large : celle de la construction de l’État-nation, entre nationalisme et cosmopolitisme. L’article s’intéresse aux idéaux de nation et de cuisine cohabitant dans deux des livres de recettes francisés du XIXe siècle au Mexique : l’Arte novísimo de cocina et le Nuevo cocinero americano/mexicano en forma de diccionario.French-fashioned Mexican recipe books in the 19th century. Globalization and construction of a national culinary modelThe first Mexican recipe books were published in the early 1830’s by French publishing houses specialized in Spanish written books. This article deals with the different nationalistic and cuisine models in two French-fashioned Mexican recipe books -the Arte novísimo de cocina and the Nuevo cocinero americano/mexicano en forma de diccionario- and their relationship with the nation-building context in nineteenth century Mexico.

  20. Cavitation on a scaled-down model of a Francis turbine guide vane: high-speed imaging and PIV measurements

    Science.gov (United States)

    Pervunin, K. S.; Timoshevskiy, M. V.; Churkin, S. A.; Kravtsova, A. Yu; Markovich, D. M.; Hanjalić, K.

    2015-12-01

    Cavitation on two symmetric foils, a NACA0015 hydrofoil and a scaled-down model of a Francis turbine guide vane (GV), was investigated by high-speed visualization and PIV. At small attack angles the differences between the profiles of the mean and fluctuating velocities for both hydrofoils were shown to be insignificant. However, at the higher angle of incidence, flow separation from the GV surface was discovered for quasi-steady regimes including cavitation-free and cavitation inception cases. The flow separation leads to the appearance of a second maximum in velocity fluctuations distributions downstream far from the GV surface. When the transition to unsteady regimes occurred, the velocity distributions became quite similar for both foils. Additionally, for the GV an unsteady regime characterized by asymmetric spanwise variations of the sheet cavity length along with alternating periodic detachments of clouds between the sidewalls of the test channel was for the first time visualized. This asymmetric behaviour is very likely to be governed by the cross instability that was recently described by Decaix and Goncalvès [8]. Moreover, it was concluded that the existence of the cross instability is independent on the test body shape and its aspect ratio.

  1. Don't pay taxes, save your money!

    OpenAIRE

    Bradáč, Michal

    2011-01-01

    Bachelor thesis "Don't Pay Taxes, Save Your Money!" focuses on the impact of the existence of tax havens on private and public sector. On the theoretical level, it shows the attractivity of tax havens for sufficiently large firms that can afford to pay costs of tax planning and profit manipulations. On the empirical level, it shows that tax havens are really the most successful jurisdictions in attracting foreign investors. In the end, two models of tax competition are introduced in order to ...

  2. Digitaalisen markkinointiviestinnän suunnittelu Facebookissa: Ravintola Don Corleone

    OpenAIRE

    Dondych, Fanny

    2016-01-01

    Tämän opinnäytetyön tavoitteena oli kehittää viestintäsuunnitelma ravintolalle Don Corleone digi-taalisesta markkinointiviestinnästä Facebookissa. Työn tarkoituksena oli tehostaa ravintolan mark-kinointiviestintää Facebookissa, mikä johtaisi asiakkaiden lisääntymiseen ja sitä kautta liiketoimin-nan kasvuun. Sosiaalisen median palveluista viestintäkanavaksi valittiin Facebook toimeksiantajan toiveesta sekä Facebookin suuren suosion ja soveltuvuuden vuoksi. Facebookissa on valmiiksi pal-jon eri...

  3. Aspectos literarios de la obra de don Joan de Castellanos

    Directory of Open Access Journals (Sweden)

    Mario Germán Romero

    1966-09-01

    Full Text Available Capítulo XIV Voces castizas que no figuran en el diccionario de la academia (I Con el título de Dos mil quinientas voces castizas y bien autorizadas que piden lugar en nuestro léxico, publicó don Francisco Rodríguez Marín un interesante libro en Madrid, 1922. El erudito comentador del Quijote estudió cuidadosamente los autores españoles de los siglos XV, XVI y XVII.

  4. Signs of revision in Don Quixote, Part II

    Directory of Open Access Journals (Sweden)

    Gonzalo Pontón

    2016-11-01

    Full Text Available This article provides new evidences in favour of the hypothesis that Cervantes, after finishing Don Quixote, Part II, partially revised the original, introducing some significant changes and additions, mainly in the last chapters. The analysis of some narrative inconsistencies, that cannot be interpreted as mere mistakes but as significant textual traces, reveals a process of re-elaboration –a process that affects at least four sections of the novel. Most of the evidence gathered here suggests that this revision is closely linked to Avellaneda’s continuation, in the sense that Cervantes tried to challenge the apocriphal Quixote making last-time interventions in his own text.

  5. Don Favareau and the Road to Biosemiotic Transdisciplinarity

    DEFF Research Database (Denmark)

    Brier, Søren

    2017-01-01

    Don Favareau has been a dynamic contributor to the development of biosemiotics its organization, not only with his seminal book: Essential Readings in Biosemiotic: Anthology and Commentary from 2010, where he edited all his colleagues’ writings creating the history of biosemiotics. He has assumed...... the role of the modest and benevolent interdisciplinary integrator through his pervasive kindness and openness to all serious initiatives. Always he is considering where a specific contribution could fit in to the overall development of biosemiotics and pondering how a change in the foundation of science...

  6. Don, Betty and Jackie Kennedy: On Mad Men and Periodisation

    Directory of Open Access Journals (Sweden)

    Prudence Black

    2012-09-01

    Full Text Available Why is it that we watch Mad Men and think it represents a period? Flashes of patterned wallpaper, whiskey neat, babies born that are never mentioned, contact lining for kitchen drawers, Ayn Rand, polaroids, skinny ties, Hilton hotels, Walter Cronkite, and a time when Don Draper can ask ‘What do women want?’ and dry old Roger Sterling can reply ‘Who Cares?’ This essay explores the embrace of period detail in Mad Men finding it to be both loving and fetishistic, and belonging, like all period film, to the politics of the present.

  7. The Generation of 1898 and Cervantes : The invention of Don Quixote as a national symbol

    NARCIS (Netherlands)

    Storm, H.J.; Achiri, N.; Baraibar, A.; Schmelzer, F.K.E.

    2015-01-01

    Don Quixote became a Spanish national symbol thanks to the authors the Generation of 1898, such as Miguel de Unamuno, Azorín and Francisco Navarra Ledesma, who published their new interpretations during the 1905 commemoration of the publication of Cervantes', The Ingenious Gentleman Don Quixote of

  8. Le Don De Corps En Cote D\\'ivoire | Broalet | African Journal of ...

    African Journals Online (AJOL)

    Introduction Le don de corps qui permet de se procurer le matériel anatomique de dissection que constitue le cadavre humain n\\'existe pas en Afrique noire et notamment en Cote d\\' Ivoire. Objectif Recueillir des informations sur le don de corps à Abidjan. Méthode Les auteurs rapportent les informations recueillies au cours ...

  9. T198. A SCHIZOPHRENIA-LIKE BIRTH SEASONALITY AMONG MATHEMATICIANS AND AN OPPOSITE SEASONALITY AMONG BIOLOGISTS: MORE EVIDENCE IMPLICATING BIMODAL RHYTHMS OF GENERAL BIRTHS

    Science.gov (United States)

    Marzullo, Giovanni

    2018-01-01

    -20th century born American scientists and among yet earlier European biologists and mathematicians. Results A group representing 1,925 American scientists showed the SCZ-resistance, GP2-coincident seasonality. However, this effect proved to be mostly due to biologists because biochemists, chemists, and physicists showed gradually less seasonality while mathematicians suggested an altogether artist-like, GP1-coincident seasonality. This intimation of a biologist-mathematician antithesis was pursued with an investigation of most major figures in the history of the two sciences from the 15th to the early-20th century. The two groups, numbering 576 mathematicians and 787 biologists, shared the same mean decade of birth, the 1780s, and essentially the same geographic origin in Western Europe. The mathematicians showed a very significant SCZ liability-like, GP1-coincident seasonality while the biologists showed an even more significant SCZ resistance-like, GP2-coincident seasonality. The latter effect was particularly strong among naturalists, anatomists and other groups representing biological “observationalism” as opposed to “experimentalism.” Discussion The findings are discussed in light of a) new evidence that the annual photoperiod is indeed alone responsible for both peaks of general births, with the GP1 and the GP2 being caused by maternal periconceptional exposure to, respectively, the summer-solstice sunlight maximum and the winter-solstice minimum, and b) an approach/withdrawal theory of lateralization of basic emotions where the left cerebral cortex would handle external stimuli eliciting complacent emotions towards external realities while the right cortex would handle internal stimuli eliciting disdain for those realities.

  10. Blood Pressure Medicines Don’t Work If People Don’t Take Them PSA (:60)

    Centers for Disease Control (CDC) Podcasts

    2016-09-13

    This 60 second public service announcement is based on the September 2016 CDC Vital Signs report. Blood pressure medicines don’t work if people don’t take them. Learn how health care systems can work with patients to make taking medicines easier.  Created: 9/13/2016 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 9/13/2016.

  11. 77 FR 37031 - Don W. Gilbert Hydro Power, LLC; Notice of Application Tendered for Filing With the Commission...

    Science.gov (United States)

    2012-06-20

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 14367-001] Don W. Gilbert... No.: 14367-001. c. Date filed: May 30, 2012. d. Applicant: Don W. Gilbert Hydro Power, LLC. e. Name... Utility Regulatory Policies Act of 1978, 16 U.S.C. 2705, 2708.] h. Applicant Contact: Don W. Gilbert and...

  12. Microbial Detoxification of Deoxynivalenol (DON), Assessed via a Lemna minor L. Bioassay, through Biotransformation to 3-epi-DON and 3-epi-DOM-1.

    Science.gov (United States)

    Vanhoutte, Ilse; De Mets, Laura; De Boevre, Marthe; Uka, Valdet; Di Mavungu, José Diana; De Saeger, Sarah; De Gelder, Leen; Audenaert, Kris

    2017-02-13

    Mycotoxins are toxic metabolites produced by fungi. To mitigate mycotoxins in food or feed, biotransformation is an emerging technology in which microorganisms degrade toxins into non-toxic metabolites. To monitor deoxynivalenol (DON) biotransformation, analytical tools such as ELISA and liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) are typically used. However, these techniques do not give a decisive answer about the remaining toxicity of possible biotransformation products. Hence, a bioassay using Lemna minor L. was developed. A dose-response analysis revealed significant inhibition in the growth of L. minor exposed to DON concentrations of 0.25 mg/L and higher. Concentrations above 1 mg/L were lethal for the plant. This bioassay is far more sensitive than previously described systems. The bioassay was implemented to screen microbial enrichment cultures, originating from rumen fluid, soil, digestate and activated sludge, on their biotransformation and detoxification capability of DON. The enrichment cultures originating from soil and activated sludge were capable of detoxifying and degrading 5 and 50 mg/L DON. In addition, the metabolites 3-epi-DON and the epimer of de-epoxy-DON (3-epi-DOM-1) were found as biotransformation products of both consortia. Our work provides a new valuable tool to screen microbial cultures for their detoxification capacity.

  13. Microbial Detoxification of Deoxynivalenol (DON, Assessed via a Lemna minor L. Bioassay, through Biotransformation to 3-epi-DON and 3-epi-DOM-1

    Directory of Open Access Journals (Sweden)

    Ilse Vanhoutte

    2017-02-01

    Full Text Available Mycotoxins are toxic metabolites produced by fungi. To mitigate mycotoxins in food or feed, biotransformation is an emerging technology in which microorganisms degrade toxins into non-toxic metabolites. To monitor deoxynivalenol (DON biotransformation, analytical tools such as ELISA and liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS are typically used. However, these techniques do not give a decisive answer about the remaining toxicity of possible biotransformation products. Hence, a bioassay using Lemna minor L. was developed. A dose–response analysis revealed significant inhibition in the growth of L. minor exposed to DON concentrations of 0.25 mg/L and higher. Concentrations above 1 mg/L were lethal for the plant. This bioassay is far more sensitive than previously described systems. The bioassay was implemented to screen microbial enrichment cultures, originating from rumen fluid, soil, digestate and activated sludge, on their biotransformation and detoxification capability of DON. The enrichment cultures originating from soil and activated sludge were capable of detoxifying and degrading 5 and 50 mg/L DON. In addition, the metabolites 3-epi-DON and the epimer of de-epoxy-DON (3-epi-DOM-1 were found as biotransformation products of both consortia. Our work provides a new valuable tool to screen microbial cultures for their detoxification capacity.

  14. Vivisection au ralenti: Don DeLillo’s Point Omega

    Directory of Open Access Journals (Sweden)

    Ruxanda BONTILĂ

    2014-12-01

    Full Text Available Reading a Don DeLillo is like walking on glass, that is, you need hold your breath so that nothing could deter you from focusing on the mission, if you want to keep safe and mostly sound. The writer’s latest novel, Point Omega (2010, is no exception in that its author engages once more in the exercise of stripping away all surfaces so as to let us see into the terror of what he calls “makeshift reality”—his characters’ and ours. The claims I advance and substantiate in the essay, refer to (1 how a fluid chronology sustained by framing devices adds to the understanding of the construct of a novel/film in progress; (2 how the shifting narrative perspective ensures a vivisectionist’s look into the body of life/death/world. Don DeLillo’s novel is another terrifying X-ray of war/life/death as agonizing nothingness which literature in its ‘late-phase’ is meant to cure.

  15. ‘Early Psychosis’ as a Mirror of Biologist Controversies in Post-WarGerman, Anglo-Saxon and Soviet Psychiatry

    Directory of Open Access Journals (Sweden)

    Lara eRzesnitzek

    2013-07-01

    Full Text Available The English term ‘early psychosis’ was coined in the 1930s to refer to feelings of irritability, loss of concentration, hypochondriac ideas, moodiness and lassitude that were seen to precede the onset of clear-cut hallucinations and delusions. The history of thinking about ‘early psychosis’ under names such as ‘latent’, ‘masked’, ‘mild’, ‘simple’ or ‘sluggish’ schizophrenia before World War II and afterwards on the different sides of the Wall and the Iron Curtain reveals ‘early psychosis’ as a mirror of quite aged international biologist controversies that are still alive today and to the same extent as they are misunderstood, are influential in their implications in today’s psychiatry.

  16. Experimental evidence of inter-blade cavitation vortex development in Francis turbines at deep part load condition

    Science.gov (United States)

    Yamamoto, K.; Müller, A.; Favrel, A.; Avellan, F.

    2017-10-01

    Francis turbines are subject to various types of cavitation flow depending on the operating condition. To enable a smooth integration of the renewable energy sources, hydraulic machines are now increasingly required to extend their operating range, especially down to extremely low discharge conditions called deep part load operation. The inter-blade cavitation vortex is a typical cavitation phenomenon observed at deep part load operation. However, its dynamic characteristics are insufficiently understood today. In an objective of revealing its characteristics, the present study introduces a novel visualization technique with instrumented guide vanes embedding the visualization devices, providing unprecedented views on the inter-blade cavitation vortex. The binary image processing technique enables the successful evaluation of the inter-blade cavitation vortex in the images. As a result, it is shown that the probability of the inter-blade cavitation development is significantly high close to the runner hub. Furthermore, the mean vortex line is calculated and the vortex region is estimated in the three-dimensional domain for the comparison with numerical simulation results. In addition, the on-board pressure measurements on a runner blade is conducted, and the influence of the inter-blade vortex on the pressure field is investigated. The analysis suggests that the presence of the inter-blade vortex can magnify the amplitude of pressure fluctuations especially on the blade suction side. Furthermore, the wall pressure difference between pressure and suction sides of the blade features partially low or negative values near the hub at the discharge region where the inter-blade vortex develops. This negative pressure difference on the blade wall suggests the development of a backflow region caused by the flow separation near the hub, which is closely related to the development of the inter-blade vortex. The development of the backflow region is confirmed by the numerical

  17. SCAN TO BIM FOR 3D RECONSTRUCTION OF THE PAPAL BASILICA OF SAINT FRANCIS IN ASSISI IN ITALY

    Directory of Open Access Journals (Sweden)

    M. G. Angelini

    2017-05-01

    Full Text Available The historical building heritage, present in the most of Italian cities centres, is, as part of the construction sector, a working potential, but unfortunately it requires planning of more complex and problematic interventions. However, policies to support on the existing interventions, together with a growing sensitivity for the recovery of assets, determine the need to implement specific studies and to analyse the specific problems of each site. The purpose of this paper is to illustrate the methodology and the results obtained from integrated laser scanning activity in order to have precious architectural information useful not only from the cultural heritage point of view but also to construct more operative and powerful tools, such as BIM (Building Information Modelling aimed to the management of this cultural heritage. The Papal Basilica and the Sacred Convent of Saint Francis in Assisi in Italy are, in fact, characterized by unique and complex peculiarities, which require a detailed knowledge of the sites themselves to ensure visitor’s security and safety. For such a project, we have to take in account all the people and personnel normally present in the site, visitors with disabilities and finally the needs for cultural heritage preservation and protection. This aim can be reached using integrated systems and new technologies, such as Internet of Everything (IoE, capable of connecting people, things (smart sensors, devices and actuators; mobile terminals; wearable devices; etc., data/information/knowledge and processes to reach the desired goals. The IoE system must implement and support an Integrated Multidisciplinary Model for Security and Safety Management (IMMSSM for the specific context, using a multidisciplinary approach.

  18. Scan to Bim for 3d Reconstruction of the Papal Basilica of Saint Francis in Assisi in Italy

    Science.gov (United States)

    Angelini, M. G.; Baiocchi, V.; Costantino, D.; Garzia, F.

    2017-05-01

    The historical building heritage, present in the most of Italian cities centres, is, as part of the construction sector, a working potential, but unfortunately it requires planning of more complex and problematic interventions. However, policies to support on the existing interventions, together with a growing sensitivity for the recovery of assets, determine the need to implement specific studies and to analyse the specific problems of each site. The purpose of this paper is to illustrate the methodology and the results obtained from integrated laser scanning activity in order to have precious architectural information useful not only from the cultural heritage point of view but also to construct more operative and powerful tools, such as BIM (Building Information Modelling) aimed to the management of this cultural heritage. The Papal Basilica and the Sacred Convent of Saint Francis in Assisi in Italy are, in fact, characterized by unique and complex peculiarities, which require a detailed knowledge of the sites themselves to ensure visitor's security and safety. For such a project, we have to take in account all the people and personnel normally present in the site, visitors with disabilities and finally the needs for cultural heritage preservation and protection. This aim can be reached using integrated systems and new technologies, such as Internet of Everything (IoE), capable of connecting people, things (smart sensors, devices and actuators; mobile terminals; wearable devices; etc.), data/information/knowledge and processes to reach the desired goals. The IoE system must implement and support an Integrated Multidisciplinary Model for Security and Safety Management (IMMSSM) for the specific context, using a multidisciplinary approach.

  19. Embryotoxicity Caused by DON-Induced Oxidative Stress Mediated by Nrf2/HO-1 Pathway

    Directory of Open Access Journals (Sweden)

    Miao Yu

    2017-06-01

    Full Text Available Deoxynivalenol (DON belongs to the type B group of trichothecenes family, which is composed of sesquiterpenoid metabolites produced by Fusarium and other fungi in grain. DON may cause various toxicities, such as cytotoxicity, immunotoxicity, genotoxicity as well as teratogenicity and carcinogenicity. In the present study, we focus on a hypothesis that DON alters the expressions of Nrf2/HO-1 pathway by inducing embryotoxicity in C57BL/6 mouse (5.0, 2.5, 1.0, and 0 mg/kg/day and BeWo cell lines (0 and 50 nM; 3 h, 12 h and 24 h. Our results indicate that DON treatment in mice during pregnancy leads to ROS accumulation in the placenta, which results in embryotoxicity. At the same time Nrf2/HO-1 pathway is up-regulated by ROS to protect placenta cells from oxidative damage. In DON-treated BeWo cells, the level of ROS has time–effect and dose–effect relationships with HO-1 expression. Moderate increase in HO-1 protects the cell from oxidative damage, while excessive increase in HO-1 aggravates the oxidative damage, which is called in some studies the “threshold effect”. Therefore, oxidative stress may be the critical molecular mechanism for DON-induced embryotoxicity. Besides, Nrf2/HO-1 pathway accompanied by the “threshold effect” also plays an important role against DON-induced oxidative damage in this process.

  20. Studies on phytosterol content of Parkia roxburgii G. Don.

    Directory of Open Access Journals (Sweden)

    DJADJAT TISNADJAJA

    2006-01-01

    Full Text Available Kedawung (Parkia roxburgii G. Don. is one of plants that originally could be found in almost all parts of Java Island. Due to lack of attention, at present situation this plant could be categorized as an endangered species. This plant species distributed widely in Africa. In several African countries, this plant has an important position either as food resource or alternative medicine. In Indonesia, traditionally kedawung tree often use as medicine, especially as part of “jamu gendong” formulation. This work was focused on the study of phytosterol content and it distribution. The research result show that almost all parts of kedawung tree have a significant content of phytosterol, which is dominated by beta-sitosterol. The highest beta-sitosterol content was founded in the stem of leaf (35.24% (w/w and pod (29.67% (w/w.

  1. Don Giovanni Goes to Prison: Teaching Opera behind Bars

    Directory of Open Access Journals (Sweden)

    Pierpaolo Polzonetti

    2016-12-01

    Full Text Available Teaching opera in prison presents challenges, such as limits imposed on printed and recorded material to study it, or the audio-visual technology in the classroom space, yet, no other experience can be so inspiring and rewarding for everybody involved. This essay focuses on teaching opera, in particular Mozart’s Don Giovanni, to imprisoned students in America. It addresses pedagogical challenges on how to teach opera in prison and advocates for the need to leave the ivory tower of academia and engage in social action. If opera is still perceived as an elitist art form, it is because it is artificially kept that way by being practiced, taught, studied, and promoted only among an exclusive sector of our population.

  2. Plantlets from encapsulated shoot buds of Catalpa ovata G. Don

    Directory of Open Access Journals (Sweden)

    Halina Wysokińska

    2014-01-01

    Full Text Available Shoot buds isolated from in vitro shoot cultures of Catalpa ovata G. Don were encapsulated using 3% sodium alginate with sucrose (3% and 50 mM calcium chloride. The morphogenic response of encapsulated buds was affected by such factors, like composition of the media and the presence of growth regulators. The highest frequency of plantlet germination from encapsulated buds (70% within 4 weeks was obtained on Woody Plant medium (WP (Lloyd and McCown 1980 containing indole-3-butyric acid (IBA (1 mg/l. The process was substantially inhibited by cold-storage (4oC of encapsulated buds. In this case, the frequency response ranged from 3% to 22% dependent on storage period (28 or 42 days and the presence of the paraffin coat covering the alginate capsules. The plantlets developed from both unstored and stored encapsulated buds of C. ovata were transplanted to soil and grew in pots to phenotypically normal plants.

  3. Efectos embriotóxicos de Picrosia longifolia Don (Asteraceae

    Directory of Open Access Journals (Sweden)

    Victor Benavides

    2014-06-01

    Full Text Available Se ha evaluado los probables efectos tóxicos del extracto acuoso de Picrosia longifolia Don “Achicoria” sobre el desarrollo de embriones preimplantacionales de ratón. Extracto acuoso de P. longifolia al 20%, 10% y 0% fue suministrado a ratonas preñadas hasta las 86 horas postcópula (hpc. Al evaluar el estadio embrionario se encontró que el extracto acuoso de P. longifolia al 10% y 20% causó retraso en el desarrollo embrionario. También se observó una disminución en la viabilidad embrionaria en los grupos tratados. Tanto la disminución de viabilidad como el retraso en el desarrollo se produjo en una forma dosis dependiente.

  4. Mission Analysis for the Don Quijote Phase-A Study

    Science.gov (United States)

    Cano, Juan L.; Sanchez, Mariano; Cornara, Stefania; Carnelli, Ian

    2007-01-01

    The Don Quijote Phase-A study is a definition study funded by ESA and devoted to the analysis of the possibilities to deflect a Near Earth Object (NEO) in the range of 300-800 m diameter. DEIMOS Space S.L. and EADS Astrium have teamed up within this study to form one of the three consortia that have analyzed these aspects for ESA. Target asteroids for the mission are 1989 ML, 2002 AT4 and Apophis. This paper presents the mission analysis activities within the consortium providing: low-thrust interplanetary rendezvous Orbiter trajectories to the target asteroids, ballistic interplanetary trajectories for the Impactor, Orbiter arrival description at the asteroids, Orbiter stable orbits characterization at the asteroid, deflection determination by means of a Radio Science Experiment (RSE) as well as the mission timelines and overall mission scenarios.

  5. Volatiles of Helichrysum italicum (Roth) G. Don from Croatia.

    Science.gov (United States)

    Zeljković, Sanja Ćavar; Šolić, Marija Edita; Maksimović, Milka

    2015-01-01

    Helichrysum italicum (Roth) G. Don is a flowering plant of the family Asteraceae. It is rich in oil that is used for different medicinal purposes and in fragrance industry. Volatile profile of four populations of H. italicum, collected from natural habitat in Dalmatia (Croatia), was analysed by capillary GC-MS. Sample from BraČ Island had α-trans-bergamotene (10.2%) and β-acoradiene (10.1%) as the majors, whereas sample collected on Biokovo Mt. was rich in neryl acetate (8.1%). β-Acoradiene was also the main constituent of sample collected near Tijarica, whereas rosifoliol (8.5%) was the most abundant constituent in sample collected near Makarska. Presented results show the influence of environmental conditions on chemical differentiation of the volatiles of H. italicum from Croatia.

  6. Scientific Communication for Positive Action: Do's and Don'ts

    Science.gov (United States)

    Sanquini, A.; Wood, M. M.

    2015-12-01

    Natural hazard presentations often highlight disasters that may ensue from natural processes when mitigation or preparedness actions are not taken. Examples include images of raging fires, collapsed buildings, and flooded urban areas. Research has shown that this makes presentations more interesting and more memorable. Such images are the stock and trade of disaster reporting by the media. Unfortunately, it may also trigger avoidance and denial in the audience, resulting in preparedness reduction; the opposite effect of what may have been intended by the speaker. Recent social research has provided insight into a better approach. The theory of communicating actionable risk posits that people will take action against hazards when they know what to do, think it would work, and know someone who did it. This approach was recently applied in an intervention designed to motivate earthquake-resistant construction in Kathmandu Valley, Nepal. Social theory further suggests that a tendency towards action is strengthened by hearing a consistent message over time, and by providing the audience with an appropriate opportunity to seek out relevant information. This presentation shows how, by taking this transdisciplinary step, scientists can make small changes in their hazard communication, thereby acting as positive influencers of change. A summary of "do's" and "don'ts" is given for reference. 1. Show examples of what to do. 2. Show effectiveness of actions. 3. Give sense of knowing someone who did it. 4. Deliver consistent message, repeatedly. 5. Give opportunity for more information. DON'T: 1. Make the disaster the star. 2. Contradict other communications.

  7. Hydro-acoustic resonance behavior in presence of a precessing vortex rope: observation of a lock-in phenomenon at part load Francis turbine operation

    International Nuclear Information System (INIS)

    Favrel, A; Landry, C; Müller, A; Yamamoto, K; Avellan, F

    2014-01-01

    Francis turbines operating at part load condition experience the development of a cavitating helical vortex rope in the draft tube cone at the runner outlet. The precession movement of this vortex rope induces local convective pressure fluctuations and a synchronous pressure pulsation acting as a forced excitation for the hydraulic system, propagating in the entire system. In the draft tube, synchronous pressure fluctuations with a frequency different to the precession frequency may also be observed in presence of cavitation. In the case of a matching between the precession frequency and the synchronous surge frequency, hydro-acoustic resonance occurs in the draft tube inducing high pressure fluctuations throughout the entire hydraulic system, causing torque and power pulsations. The risk of such resonances limits the possible extension of the Francis turbine operating range. A more precise knowledge of the phenomenon occurring at such resonance conditions and prediction capabilities of the induced pressure pulsations needs therefore to be developed. This paper proposes a detailed study of the occurrence of hydro-acoustic resonance for one particular part load operating point featuring a well-developed precessing vortex rope and corresponding to 64% of the BEP. It focuses particularly on the evolution of the local interaction between the pressure fluctuations at the precession frequency and the synchronous surge mode passing through the resonance condition. For this purpose, an experimental investigation is performed on a reduced scale model of a Francis turbine, including pressure fluctuation measurements in the draft tube and in the upstream piping system. Changing the pressure level in the draft tube, resonance occurrences are highlighted for different Froude numbers. The evolution of the hydro-acoustic response of the system suggests that a lock-in effect between the excitation frequency and the natural frequency may occur at low Froude number, inducing a hydro

  8. Re-diseño de la línea de ejes de turbinas Francis de salto elevado para la mejora de su competitividad

    OpenAIRE

    GARCÍA MÓNACO, ALEJANDRO

    2015-01-01

    El objetivo de este proyecto es mejorar la línea de ejes de las turbinas Francis de eje horizontal. En especial, se ha trabajado con aquellas máquinas diseñadas para funcionar con saltos de agua elevados. El proyecto surge del conocimiento de importantes ventajas económicas de las turbinas horizontales frente a las verticales y de la voluntad por parte de ALSTOM HYDRO de mejorar los rendimientos de las primeras para hacerlas más competitivas. Los capítulos 3 y 4 son introductorios a la pro...

  9. Espíritos cheios de bichos: A fauna nas viagens de Louis Agassiz e Richard Francis Burton pelo Brasil oitocentista

    Directory of Open Access Journals (Sweden)

    Janaina Zito Losada

    2015-04-01

    Full Text Available O Brasil do século XIX foi alvo de inúmeras viagens realizadas por cientistas estrangeiros. O objetivo deste artigo é analisar as impressões sobre a fauna brasileira presentes nos relatos das viagens realizadas pelo naturalista suíço Louis Agassiz, em 1865, e pelo explorador inglês Richard Francis Burton, em 1868. Destes relatos privilegiam-se as descrições do meio natural de diferentes regiões brasileiras e das particularidades da fauna silvestre por eles encontrada.

  10. Journey of a molecular biologist.

    Science.gov (United States)

    Nomura, Masayasu

    2011-01-01

    My journey into a research career began in fermentation biochemistry in an applied science department during the difficult post-World War II time in Japan. Subsequently, my desire to do research in basic science developed. I was fortunate to be a postdoctoral fellow in the United States during the early days of molecular biology. From 1957 to 1960, I worked with three pioneers of molecular biology, Sol Spiegelman, James Watson, and Seymour Benzer. These experiences helped me develop into a basic research scientist. My initial research projects at Osaka University, and subsequently at the University of Wisconsin, Madison, were on the mode of action of colicins as well as on mRNA and ribosomes. Following success in the reconstitution of ribosomal subunits, my efforts focused more on ribosomes, initially on the aspects of structure, function, and in vitro assembly, such as the construction of the 30S subunit assembly map. After this, my laboratory studied the regulation of the synthesis of ribosomes and ribosomal components in Escherichia coli. Our achievements included the discovery of translational feedback regulation of ribosomal protein synthesis and the identification of several repressor ribosomal proteins used in this regulation. In 1984, I moved to the University of California, Irvine, and initiated research on rRNA transcription by RNA polymerase I in the yeast Saccharomyces cerevisiae. The use of yeast genetics combined with biochemistry allowed us to identify genes uniquely involved in rRNA synthesis and to elucidate the mechanism of initiation of transcription. This essay is a reflection on my life as a research scientist.

  11. Reproducible Bioinformatics Research for Biologists

    Science.gov (United States)

    This book chapter describes the current Big Data problem in Bioinformatics and the resulting issues with performing reproducible computational research. The core of the chapter provides guidelines and summaries of current tools/techniques that a noncomputational researcher would need to learn to pe...

  12. NMR for chemists and biologists

    CERN Document Server

    Carbajo, Rodrigo J

    2013-01-01

    This book offers a concise introduction to the field of nuclear magnetic resonance or NMR. It presents the basic foundations of NMR in a non-mathematical way and provides an overview of both recent and important biological applications of NMR.

  13. Don Bates: the medical historian as educator, activist, and historian of science.

    Science.gov (United States)

    Weisz, George

    2009-01-01

    The author outlines the academic and extra-academic career of Don Bates as a physician-historian, political activist, and creator of the interdisciplinary Department of Social Studies of Medicine at McGill University.

  14. Don't make me think: a common sense approach to Web usability

    National Research Council Canada - National Science Library

    Krug, Steve

    2006-01-01

    .... To ensure that your sites provide that experience, this guide from usability guru Krug distills his years of on-the-job experience into a practical primer on the do's and don'ts of good Web design...

  15. Have a Baby or Young Child With a Cold? Most Don't Need Medicines

    Science.gov (United States)

    ... Products For Consumers Home For Consumers Consumer Updates Most Young Children With a Cough or Cold Don' ... cold? It depends on the child’s age. Although most colds in children don’t have serious complications, ...

  16. ???????????? ? ?????????? ??????? ??????? ?? ??????? ???????????? ? ?????? ???????-??-???? // Advantages and disadvantages of franchise business opportunities in Rostov-on-don

    OpenAIRE

    Bugayan, S.A.; Filimonenko, I.

    2013-01-01

    ? ?????? ??????????? ???????? ???????????? ? ?????????? ??????????? ??????? ?? ??????? ???????????? ? ?????? ???????-??-???? ?? ??????? ????????? ????, ????????????? ??????? ???? ????? ??????? ? ?? ?????????? ??????????? ????????. In this article are considered main cons and pros of franchise business opportunities in Rostov-on-Don, using different businesses as an example,efficiency of this type of business and its future possibilities.

  17. Buy, don't build -- What does that mean for a software developer?

    International Nuclear Information System (INIS)

    Little, T.; Rahi, M.A.; Sinclair, C.

    1995-01-01

    The buzz phrase of the 1990's for the petroleum software industry has become ''buy, don't build.'' For an end user in an oil company, this generally means acquiring application software rather than developing it internally. The concept of buy, don't build can also apply for a software developer. Purchasing software toolkit components can expedite the development of an application as well as reduce future support requirements

  18. Mixing regime as a key factor to determine DON formation in drinking water biological treatment.

    Science.gov (United States)

    Lu, Changqing; Li, Shuai; Gong, Song; Yuan, Shoujun; Yu, Xin

    2015-11-01

    Dissolved organic nitrogen (DON) can act as precursor of nitrogenous disinfection by-products formed during chlorination disinfection. The performances of biological fluidized bed (continuous stirred tank reactor, CSTR) and bio-ceramic filters (plug flow reactor, PFR) were compared in this study to investigate the influence of mixing regime on DON formation in drinking water treatment. In the shared influent, DON ranged from 0.71mgL(-1) to 1.20mgL(-1). The two biological fluidized bed reactors, named BFB1 (mechanical stirring) and BFB2 (air agitation), contained 0.12 and 0.19mgL(-1) DON in their effluents, respectively. Meanwhile, the bio-ceramic reactors, labeled as BCF1 (no aeration) and BCF2 (with aeration), had 1.02 and 0.81mgL(-1) DON in their effluents, respectively. Comparative results showed that the CSTR mixing regime significantly reduced DON formation. This particular reduction was further investigated in this study. The viable/total microbial biomass was determined with propidium monoazide quantitative polymerase chain reaction (PMA-qPCR) and qPCR, respectively. The results of the investigation demonstrated that the microbes in BFB2 had higher viability than those in BCF2. The viable bacteria decreased more sharply than the total bacteria along the media depth in BCF2, and DON in BCF2 accumulated in the deeper media. These phenomena suggested that mixing regime determined DON formation by influencing the distribution of viable, total biomass, and ratio of viable biomass to total biomass. Copyright © 2014 Elsevier Ltd. All rights reserved.

  19. Science 101: Why Don't Spiders Stick to Their Own Webs?

    Science.gov (United States)

    Robertson, Bill

    2011-01-01

    This article explains why spiders don't stick to their webs. Spiders don't get stuck in their own webs (and they aren't immune to their own glue) because they use a combination of sticky and nonsticky threads (different glands for producing those), and the glue is in droplets that the spider can avoid but the prey can't. The spider's nervous…

  20. Effect of test exercises and mask donning on measured respirator fit.

    Science.gov (United States)

    Crutchfield, C D; Fairbank, E O; Greenstein, S L

    1999-12-01

    Quantitative respirator fit test protocols are typically defined by a series of fit test exercises. A rationale for the protocols that have been developed is generally not available. There also is little information available that describes the effect or effectiveness of the fit test exercises currently specified in respiratory protection standards. This study was designed to assess the relative impact of fit test exercises and mask donning on respirator fit as measured by a controlled negative pressure and an ambient aerosol fit test system. Multiple donnings of two different sizes of identical respirator models by each of 14 test subjects showed that donning affects respirator fit to a greater degree than fit test exercises. Currently specified fit test protocols emphasize test exercises, and the determination of fit is based on a single mask donning. A rationale for a modified fit test protocol based on fewer, more targeted test exercises and multiple mask donnings is presented. The modified protocol identified inadequately fitting respirators as effectively as the currently specified Occupational Safety and Health Administration (OSHA) quantitative fit test protocol. The controlled negative pressure system measured significantly (p < 0.0001) more respirator leakage than the ambient aerosol fit test system. The bend over fit test exercise was found to be predictive of poor respirator fit by both fit test systems. For the better fitting respirators, only the talking exercise generated aerosol fit factors that were significantly lower (p < 0.0001) than corresponding donning fit factors.

  1. Fuel elements assembling for the DON project exponential experience; Montaje de los elementos combustibles para la experiencia exponencial del proyecto DON

    Energy Technology Data Exchange (ETDEWEB)

    Anca Abati, R de

    1966-07-01

    It is described the fuel unit used in the DON exponential experience, the manufacturing installments and tools as well as the stages in the fabrication.These 74 elements contain each 19 cartridges loaded with synterized urania, uranium carbide and indium, gold, and manganese probes. They were arranged in calandria-like tubes and the process-tube. This last one containing a cooling liquid simulating the reactor organic. Besides being used in the DON reactor exponential experience they were used in critic essays by the substitution method in the French reactor AQUILON II. (Author) 6 refs.

  2. okoronkwo, ike francis

    African Journals Online (AJOL)

    Valued Acer Customer

    chain of events. Among these is a mass participation of people into an emerging global culture ... the enormous fluidities of location and identity, are the imperatives of existence of our age. .... searched for a plastic reality a year later and this became the beginning of sourcing imagery from electronic ..... Superpower in Africa.

  3. Making and Selling the “Rock Star Pope”: The Celebritization of Pope Francis during His Five-Day Visit to the Philippines

    Directory of Open Access Journals (Sweden)

    Gerry M. Lanuza

    2017-12-01

    Full Text Available This paper is an attempt to provide an analysis of the celebritization and celebrification of Pope Francis when he visited the Philippines from January 15 to 19, 2015. Employing the analytic concept of “culture industry” developed by the members of the Frankfurt School, and combining it with the current analyses in existing celebrity study under late capitalism, this paper will show how the local giant media corporations, namely, GMA and ABS-CBN, staged a grand “media event” that nationally mediatized and publicly magnified the celebrity status of the so-called “rock star Pope.” The current study contributes to the growing literature on celebrity study by focusing on the popular and charismatic religious leader of 1.2 billion Catholics worldwide. Toward the end of this paper, consistent with the critical slant of the Frankfurt School’s critique of mass deception, it is argued that the celebrity culture that created the “spectacle” of Pope Francis must be distinguished from his prophetic message. And this must be explored in future studies.

  4. Experimental investigation of the sloshing motion of the water free surface in the draft tube of a Francis turbine operating in synchronous condenser mode

    Science.gov (United States)

    Vagnoni, Elena; Favrel, Arthur; Andolfatto, Loïc; Avellan, François

    2018-06-01

    Hydropower units may be required to operate in condenser mode to supply reactive power. In this operating mode, the water level in the turbine or pump-turbine is decreased below the runner by closing the guide vanes and injecting pressurized air. While operating in condenser mode the machine experiences power losses due to several air-water interaction phenomena which cause air losses. One of such phenomena is the sloshing motion of the water free surface below the runner in the draft tube cone of a Francis turbine. The objective of the present work is to experimentally investigate the sloshing motion of the water free surface in the draft tube cone of a reduced scale physical model of a Francis turbine operating in condenser mode. Images acquisition and simultaneous pressure fluctuation measurements are performed and an image processing method is developed to investigate amplitude and frequency of the sloshing motion of the free surface. It is found that this motion is excited at the natural frequency of the water volume and corresponds to the azimuthal wavenumber m = 1 of a rotating gravity wave. The amplitude of the motion is perturbed by wave breaking and it decreases by increasing the densimetric Froude number. The sloshing frequency slightly increases with respect to the natural frequency of the water volume by increasing the densimetric Froude number. Moreover, it results that this resonant phenomenon is not related to the torque perturbation.

  5. Authority as paradox: the transformations of Don Quijote.

    Science.gov (United States)

    Priel, Beatriz

    2006-12-01

    The author's contention is that the analysand's temporary attribution of authority to the analyst is inherent in the analytic situation; this is seen as a transitional and paradoxical form of authority pertaining neither to internal nor external reality, but dwelling in the analytic third. The author proposes a conceptualization of psychoanalytic authority as a form of aesthetic authority according to Gadamer's definitions. While the scientific and hermeneutic codes for the understanding of authority in psychoanalysis assume that the main issue at stake is the delimitation of the objectivity or the subjectivity of the analyst's knowledge, this aesthetic perspective centres on the analysand's attribution of a claim of truth to analytic interpretations, and on the experience of recognition. The experience of recognition of a possible truth is particular and context-bound, as well as self-transformational. A reading of three episodes from Cervantes's The history of Don Quixote de la Mancha illuminates the transitional and paradoxical character of aesthetic authority within a transformational dialogue. These episodes are read as dramatizations of different positions vis-à-vis the paradoxical authority that characterizes transformational dialogues.

  6. Simulating and Simulated Characters, Entangled in Don Quixote

    Directory of Open Access Journals (Sweden)

    Vicente Pérez de León

    2014-12-01

    Full Text Available One of the keys for understanding the ruling universe is the nature of the interconnected duality that governs it. It is neither completely monistic, neither absolutely nihilistic, according to the principle of the Platonic symploke (the Sophist 251, 255. The validity of the entanglement between “not everything are monisms” and the fact that reality is not completely “nihilist” will be used as a logic tool to understand the alternation in the understanding of the conclusions of the existences of several of the protagonists of the Quixote. On the one hand, it is the strange case of the suicidal shepherd Grisóstomo, in desperation for his loved Marcela, which is studied in the context of a similar case, the death of Anselmo in The Tale of Ill-advised Curiosity. On the other hand it is the case of the exemplary archetypical death of Don Quixote and his revival in Alonso Quijano “the good”, which presents a similar case of (misunderstanding of the symploke principle. In conclusion, the ontological tragedy arising from not understanding or questioning the Platonic principle of the symploke will contribute to explain the attachment, identification, and nature of the entanglement between reality and fiction in selected cervantine characters. This will be achieved by focusing in both their self-awareness as creative beings and their more or less voluntary inclusion in, or exclusion from, their own simulated realities.

  7. You Don't Look Like a Physicist

    Science.gov (United States)

    Santos, Antonio Carlos Fontes

    2017-12-01

    "You don't look like a physicist!" "Sorry, this bus only goes to the university, Sir." "Where are you going, sir?" "So, you are a university professor? But a substitute one, aren't you?" "OK, you're a professor, but do you do research?" As a person of color teaching physics in Brazil, those are some comments that I usually hear. They are consequences of stereotypes, prejudices, and discrimination, which are related but different ideas. Stereotypes indicate expectations and beliefs about an individual or a group, prejudice denotes feelings, and discrimination expresses behaviors. People are likely to be astonished whenever a Black person says that he or she is a physicist. This paper aims to raise awareness of the underrepresentation of Black physics professors and researchers in Brazil and how the lack of quality high school physics education impacts Black and poor students in Brazil. Finally, some considerations on how physics education can assist minority students in overcoming social barriers that contribute to their underrepresentation are presented.

  8. Hombres. Don Tomás Rueda Vargas

    Directory of Open Access Journals (Sweden)

    Boletin Cultural y Bibliográfico Banco de la República

    1958-07-01

    Full Text Available Quince años hizo el 25 de julio que desapareció de entre nosotros don Tomás Rueda Vargas. Su nombre, ejemplar por muchos conceptos, viene siempre nimbado de las virtudes cardinales que conformaron su tarea y su vida. Escritor nato,  sabía manejar el idioma con singular pericia sin caer en  rebuscamientos  ni  en  gongorismos. Su  pensamiento era diáfano por  lo cual no se  perdía en  el laberinto de  las palabras.   Apenas éstas eran  el dócil  instrumento para su dialéctica, para ese  generoso razo­  namiento intelectual que constituía el  Alfa  y el Omega   de  su diario batallar.

  9. WImpiBLAST: web interface for mpiBLAST to help biologists perform large-scale annotation using high performance computing.

    Directory of Open Access Journals (Sweden)

    Parichit Sharma

    Full Text Available The function of a newly sequenced gene can be discovered by determining its sequence homology with known proteins. BLAST is the most extensively used sequence analysis program for sequence similarity search in large databases of sequences. With the advent of next generation sequencing technologies it has now become possible to study genes and their expression at a genome-wide scale through RNA-seq and metagenome sequencing experiments. Functional annotation of all the genes is done by sequence similarity search against multiple protein databases. This annotation task is computationally very intensive and can take days to obtain complete results. The program mpiBLAST, an open-source parallelization of BLAST that achieves superlinear speedup, can be used to accelerate large-scale annotation by using supercomputers and high performance computing (HPC clusters. Although many parallel bioinformatics applications using the Message Passing Interface (MPI are available in the public domain, researchers are reluctant to use them due to lack of expertise in the Linux command line and relevant programming experience. With these limitations, it becomes difficult for biologists to use mpiBLAST for accelerating annotation. No web interface is available in the open-source domain for mpiBLAST. We have developed WImpiBLAST, a user-friendly open-source web interface for parallel BLAST searches. It is implemented in Struts 1.3 using a Java backbone and runs atop the open-source Apache Tomcat Server. WImpiBLAST supports script creation and job submission features and also provides a robust job management interface for system administrators. It combines script creation and modification features with job monitoring and management through the Torque resource manager on a Linux-based HPC cluster. Use case information highlights the acceleration of annotation analysis achieved by using WImpiBLAST. Here, we describe the WImpiBLAST web interface features and architecture

  10. WImpiBLAST: web interface for mpiBLAST to help biologists perform large-scale annotation using high performance computing.

    Science.gov (United States)

    Sharma, Parichit; Mantri, Shrikant S

    2014-01-01

    The function of a newly sequenced gene can be discovered by determining its sequence homology with known proteins. BLAST is the most extensively used sequence analysis program for sequence similarity search in large databases of sequences. With the advent of next generation sequencing technologies it has now become possible to study genes and their expression at a genome-wide scale through RNA-seq and metagenome sequencing experiments. Functional annotation of all the genes is done by sequence similarity search against multiple protein databases. This annotation task is computationally very intensive and can take days to obtain complete results. The program mpiBLAST, an open-source parallelization of BLAST that achieves superlinear speedup, can be used to accelerate large-scale annotation by using supercomputers and high performance computing (HPC) clusters. Although many parallel bioinformatics applications using the Message Passing Interface (MPI) are available in the public domain, researchers are reluctant to use them due to lack of expertise in the Linux command line and relevant programming experience. With these limitations, it becomes difficult for biologists to use mpiBLAST for accelerating annotation. No web interface is available in the open-source domain for mpiBLAST. We have developed WImpiBLAST, a user-friendly open-source web interface for parallel BLAST searches. It is implemented in Struts 1.3 using a Java backbone and runs atop the open-source Apache Tomcat Server. WImpiBLAST supports script creation and job submission features and also provides a robust job management interface for system administrators. It combines script creation and modification features with job monitoring and management through the Torque resource manager on a Linux-based HPC cluster. Use case information highlights the acceleration of annotation analysis achieved by using WImpiBLAST. Here, we describe the WImpiBLAST web interface features and architecture, explain design

  11. Risk Acceptance Personality Paradigm: How We View What We Don't Know We Don't Know

    Science.gov (United States)

    Massie, Michael J.; Morris, A. Terry

    2011-01-01

    The purpose of integrated hazard analyses, probabilistic risk assessments, failure modes and effects analyses, fault trees and many other similar tools is to give managers of a program some idea of the risks associated with their program. All risk tools establish a set of undesired events and then try to evaluate the risk to the program by assessing the severity of the undesired event and the likelihood of that event occurring. Some tools provide qualitative results, some provide quantitative results and some do both. However, in the end the program manager and his/her team must decide which risks are acceptable and which are not. Even with a wide array of analysis tools available, risk acceptance is often a controversial and difficult decision making process. And yet, today's space exploration programs are moving toward more risk based design approaches. Thus, risk identification and good risk assessment is becoming even more vital to the engineering development process. This paper explores how known and unknown information influences risk-based decisions by looking at how the various parts of our personalities are affected by what they know and what they don't know. This paper then offers some criteria for consideration when making risk-based decisions.

  12. The Authors of the Ingenious Hidalgo Don Quixote of La Mancha

    Directory of Open Access Journals (Sweden)

    Branka Kalenić Ramšak

    2008-12-01

    Full Text Available Even today literary criticism still considers the novel Don Quixote the first modern European novel because it fundamentally changes both the concept of literary creation and the findings regarding literary reception. Miguel de Cervantes Saavedra published the first part of his chivalric novel in 1605 in Madrid with the title El ingenioso hidalgo don Quijote de la Mancha. He published the second part, titled El ingenioso caballero don Quijote de la Mancha, ten years later (i.e., in 1615, again in Madrid. Why did Cervantes change the title in the second part of his novel and thus transform Don Quixote the hidalgo ‘nobleman’ into Don Quixote the caballero ‘knight, nobleman, horseman’? In Spanish literature of Cervantes’ time, writers often borrowed texts from one another, wrote sequels to them, and reworked them into humorous poems, jocular one-act plays, or unusual parodies. The Baroque concept of imitation was not understood as plagiarism, but rather as a positive approach to creativity. One of Cervantes’ most enthusiastic imitators was Alonso Fernández de Avellaneda. He hated Cervantes, but loved Don Quixote so much that he wrote a sequel to it in the form of a chivalric novel. In 1614, Avellaneda published his novel titled Segundo tomo del ingenioso hidalgo don Quijote de la Mancha (The Second Part of the Ingenious Hidalgo of La Mancha in Tarragona. Who is hidden behind the name Alonso Fernández de Avellaneda? To date, literary history has not been able to establish with certainty who the author of this “second part” was; this work represents the greatest literary mystery of all time in Spanish literature. In the 1960s a theory developed among Cervantes experts that for now seems to be the most convincing in determining Avellaneda’s true identity. In his article “ El Quijote y los libros” (Don Quixote and Books of 1969, Martín de Riquer presented the first well-founded hypothesis claiming that the writer Alonso Fern

  13. Dissolved organic nitrogen (DON) profile during backwashing cycle of drinking water biofiltration.

    Science.gov (United States)

    Liu, Bing; Gu, Li; Yu, Xin; Yu, Guozhong; Zhang, Huining; Xu, Jinli

    2012-01-01

    A comprehensive investigation was made in this study on the variation of dissolved organic nitrogen (DON) during a whole backwashing cycle of the biofiltration for drinking water treatment. In such a cycle, the normalized DON concentration (C(effluent)/C(influent)) was decreased from 0.98 to 0.90 in the first 1.5h, and then gradually increased to about 1.5 in the following 8h. Finally, it remained stable until the end of this 24-hour cycle. This clearly 3-stage profile of DON could be explained by three aspects as follows: (1) the impact of the backwashing on the biomass and the microbial activity; (2) the release of soluble microbial products (SMPs) during the biofiltration; (3) the competition between heterotrophic bacteria and nitrifying bacteria. All the facts supported that more DON was generated during later part of the backwashing cycle. The significance of the conclusion is that the shorter backwashing intervals between backwashing for the drinking water biofilter should further decrease the DON concentration in effluent of biofilter. Crown Copyright © 2011. Published by Elsevier B.V. All rights reserved.

  14. MFS Transporters and GABA Metabolism Are Involved in the Self-Defense Against DON in Fusarium graminearum

    Directory of Open Access Journals (Sweden)

    Qinhu Wang

    2018-04-01

    Full Text Available Trichothecene mycotoxins, such as deoxynivalenol (DON produced by the fungal pathogen, Fusarium graminearum, are not only important for plant infection but are also harmful to human and animal health. Trichothecene targets the ribosomal protein Rpl3 that is conserved in eukaryotes. Hence, a self-defense mechanism must exist in DON-producing fungi. It is reported that TRI (trichothecene biosynthesis 101 and TRI12 are two genes responsible for self-defense against trichothecene toxins in Fusarium. In this study, however, we found that simultaneous disruption of TRI101 and TRI12 has no obvious influence on DON resistance upon exogenous DON treatment in F. graminearum, suggesting that other mechanisms may be involved in self-defense. By using RNA-seq, we identified 253 genes specifically induced in DON-treated cultures compared with samples from cultures treated or untreated with cycloheximide, a commonly used inhibitor of eukaryotic protein synthesis. We found that transporter genes are significantly enriched in this group of DON-induced genes. Of those genes, 15 encode major facilitator superfamily transporters likely involved in mycotoxin efflux. Significantly, we found that genes involved in the metabolism of gamma-aminobutyric acid (GABA, a known inducer of DON production in F. graminearum, are significantly enriched among the DON-induced genes. The GABA biosynthesis gene PROLINE UTILIZATION 2-2 (PUT2-2 is downregulated, while GABA degradation genes are upregulated at least twofold upon treatment with DON, resulting in decreased levels of GABA. Taken together, our results suggest that transporters influencing DON efflux are important for self-defense and that GABA mediates the balance of DON production and self-defense in F. graminearum.

  15. Consumption as Sign in Don DeLillo’s Cosmopolis

    Directory of Open Access Journals (Sweden)

    Seyyede Fateme Mirbabazade

    2013-11-01

    Full Text Available As one of the foremost American postmodern authors, Don DeLillo tends to focus on construction of postmodern subject’s consciousness through media, technology and consumption. Nevertheless, despite many affinities between Baudrillard and DeLillo, many researches which have been done on his works have failed to theoretically analyze them from Baudrillardian perspective. Although there is affinity between Baudrillard and DeLillo, there is dissimilarity as well. While Baudrillard believes that that there is no escape for individual from the ideology of the system, DeLillo claims that there is hope for change and revolution for the individuals by their action in society, particularly by the means of art, to be more  than a cog in the machine of ideology of system. Baudrillard, as one of the most influential postmodern theorists, defines consumption as organized control of sign and one of the many ways any subject is assimilated in any given society. For Baudrillard the logic of consumption is based on social differentiation. By the logic of social differentiation, individuals distinguish themselves and obtain social prestige and standing through the purchase and use of consumer goods. In his theorization about the concept of need and value, Baudrillard finds Marx’s logics of use value (utility and functionality and exchange value (economic value inadequate to include the whole function of an object and adds the logic of sign value. Baudrillard asserts that in consumption economic exchange value (money is transformed into sign exchange value (prestige, etc.; yet this functioning is maintained by the use value. The only way out of this dilemma, Baudrillard claims, is to return to symbolic exchange which is neither a conception nor an agency, but an act of exchange and a social relation and the only approach to real human communication and understanding. Therefore this research attempts to highlights those affinities in DeLillo’s first post-9

  16. Pharmacognostical studies of leaves of Combretum albidum G. Don

    Directory of Open Access Journals (Sweden)

    Ashish S Zalke

    2013-01-01

    Full Text Available Background: Combretum albidum Don belonging to family Combretaceae is an unexplored medicinal plant in the Indian medicinal system. According to ethnobotanical information, the leaves are used in the treatment of peptic ulcer and its fruits are used in diarrhoea and dysentery. Stem bark is used in the treatment of jaundice and skin diseases. The problem encountered in standardisation of this medicinal plant is its identification by source. Materials and Methods: The pharmacognostical studies were carried out in terms of organoleptic, macroscopic, microscopic, physicochemical, florescence and phytochemical analysis. Physicochemical parameters such as total ash, moisture content and extractive values are determined by World Health Organization guidelines. The microscopic features of leaf components are observed with Nikon lab photo device with microscopic units. Results: Macroscopically, the leaves are simple, obovate in shape, acuminate apex, entire margin and smooth surface. Microscopically, the leaves showed a large vascular strand that consists of thick walled xylem elements mixed with xylem fibres and phloem which is present in a thin layer along inner and outer portions of xylem. External to the xylem occur a thin line of sclerenchyma. Powder microscopy revealed glandular trichomes in the adaxial epidermal peelings also shows the non-glandular trichomes fairly common in powder and epidermis with anisocytic stomata. Vessels elements are narrow, long, cylindrical and dense multi-seriate bordered pits. Xylem fibres are thin and long, with thick walls, which are lignified. Preliminary phytochemical screening showed the presence of carbohydrate, glycoside, saponin, flavonoid, phytosterols and phenolic compounds. Conclusions: The results of the study can serve as a valuable source of pharmacognostic information as suitable standards for identification of this plant material in future investigations and applications.

  17. 3D fluid-structure modelling and vibration analysis for fault diagnosis of Francis turbine using multiple ANN and multiple ANFIS

    Science.gov (United States)

    Saeed, R. A.; Galybin, A. N.; Popov, V.

    2013-01-01

    This paper discusses condition monitoring and fault diagnosis in Francis turbine based on integration of numerical modelling with several different artificial intelligence (AI) techniques. In this study, a numerical approach for fluid-structure (turbine runner) analysis is presented. The results of numerical analysis provide frequency response functions (FRFs) data sets along x-, y- and z-directions under different operating load and different position and size of faults in the structure. To extract features and reduce the dimensionality of the obtained FRF data, the principal component analysis (PCA) has been applied. Subsequently, the extracted features are formulated and fed into multiple artificial neural networks (ANN) and multiple adaptive neuro-fuzzy inference systems (ANFIS) in order to identify the size and position of the damage in the runner and estimate the turbine operating conditions. The results demonstrated the effectiveness of this approach and provide satisfactory accuracy even when the input data are corrupted with certain level of noise.

  18. Validation of mathematical models for predicting the swirling flow and the vortex rope in a Francis turbine operated at partial discharge

    DEFF Research Database (Denmark)

    Kuibin, P.A.; Okulov, Valery; Susan-Resiga, R.F.

    2010-01-01

    recover all this information without actually computing the full three-dimensional unsteady flow in the hydraulic turbine. As a result, we provide valuable mathematical tools for assessing the turbine behaviour at off-design operating regimes in the early stages of runner design, with computational effort......The vortex rope in a hydro turbine draft tube is one the main and strong sources of pulsations in non-optimal modes of hydro turbine operation. We examine the case of a Francis turbine model operated at partial discharge, where a strong precessing vortex rope is developed in the discharge cone...... several orders of magnitude less than the current approaches of simulating the complex turbine flow....

  19. The Language of Colours. A Semiotic Analysis of Colours and Symbolic Imagery in Francis Ford Coppola’s "Bram Stoker’s Dracula" (1992

    Directory of Open Access Journals (Sweden)

    Veronika Bernard

    2011-10-01

    Full Text Available Reviews referring to Francis Ford Coppola’s Columbia Pictures Bram Stoker’s Dracula classic of 1992 recurrently mention the images owing to the camera work of Michael Ballhaus as the striking feature of the movie and highly praise them for their thematically coherent effect.. The colours, if mentioned at all, leave reviewers undecided to sceptical when it comes to evaluating their contribution to the overall composition of the film, though. By providing a semiotic analysis of colours and symbolic imagery the below article will show how colours and imagery in their inter-relatedness create coherence and cohesion with Coppola’s interpretation of Stoker’s Dracula as a religiously inspired morality play set in the context of Victorian cultural values and self-perception.

  20. Richard Francis Burton e a inserÃÃo do kama-sutras como um manual sexual entre os vitorianos (Inglaterra, 1883)

    OpenAIRE

    Felipe Salvador Weissheimer

    2014-01-01

    Dentre os vÃrios âKama-sutrasâ difundidos no mercado, a versÃo clÃssica foi escrita por Vatsyayana (sÃculo I-IV, aproximadamente) e publicada na Inglaterra em 1883 pela Sociedade Hindu Kama-Shastra. Richard Francis Burton foi o membro de maior importÃncia na Sociedade Hindu Kama-Shastra, pois, alÃm de fomentar a publicaÃÃo, auxiliou na traduÃÃo, editou e enunciou vÃrios comentÃrios ao longo da obra. Em seus comentÃrios, percebemos que o projeto da traduÃÃo e publicaÃÃo do Kama-sutras visava e...

  1. Los usos políticos del cuerpo: los dos cuerpos del rey en la filosofía política de Francis Bacon

    Directory of Open Access Journals (Sweden)

    Silvia Manzo

    2008-01-01

    Full Text Available Como figure destacada en el complejo escenario político de la transición entre la dinastía Tudor y la dinastía Estuardo de Inglaterra, Francis Bacon (1561-1626 adoptó la teoría de los dos cuerpos del rey en sus textos políticos y jurídicos. Su uso de esta teoría tiene una estrecha conexión con conceptos centrales de su filosofía natural que testimonia la profunda conexión que Bacon encuentra entre la política y la naturaleza. En este trabajo, analizaré su utilización de la teoría medieval de los dos cuerpos del rey y la vinculación que esta tiene con el resto de la filosofía baconiana. Tomaré como eje para el análisis su discurso sobre la naturalización de los escoceses nacidos después de la subida al trono de James I, donde Bacon trata el concepto de los dos cuerpos del rey con más profundidad.As a prominent intellectual figure in the complex political arena of England, during the transition from Tudor to Stuart dinasties, Francis Bacon (1561-1626 assumes the medieval King's two bodies theory in his political and juridical writings. His use of this theory is extremely linked to central concepts of his natural philosphy, which testifies to the deep connection that Bacon finds between politics and nature. This paper addresses Bacon's use of the King's two bodies theory and its link to the rest of the Baconian philosophy. The focus of this study will be his discourse on the naturalization of Scots born after James I assumption of power, where Bacon deals more deeply with the King's two bodies theory.

  2. Don Quijote: de la prosa cervantina al teatro contemporáneo

    Directory of Open Access Journals (Sweden)

    Orazi, Veronica

    2016-12-01

    Full Text Available Study of six of the most recent and outstanding dramatisations (1999-2015 of Cervantes’s Don Quijote, such as Aventuras de Don Quijote, DQ. Don Quijote en Barcelona, El caballero de la triste figura, En un lugar de Manhattan, Elogio de la locura and En un lugar del Quijote. The analysis covers the main features of such adaptations: metanarration, metadrama, doubling of the narrative structure using other artistic languages (music, plastic arts, dance, etc., new technologies, genre hybridisation, transmediality, etc. The original text message, actualised and re-expressed by these modernisations, stands out as an atemporal one: the plays examined demonstrate its effectiveness in contemporary society and, according to the perspective of social theater, stimulate the reflection on them.

  3. Pemodelan Enterprise Architecture Sistem Informasi Akademik SMA PL Don Bosko Semarang Dengan Framework Zachman

    Directory of Open Access Journals (Sweden)

    Maria Alfonsa Chintia Dea Prananingrum

    2017-05-01

    Full Text Available Abstrak SMA PL Don Bosko Semarang belum dapat memanfaatkan teknologi komputer secara optimal karena masih menggunakan cara manual dalam pengelolaan berbagai macam data akademik sehingga memberikan masalah seperti lambatnya dalam pembuatan laporan yang menyulitkan kepala sekolah dalam pengambilan keputusan. Oleh sebab itu, SMA PL Don Bosko Semarang membutuhkan Sistem Informasi Akademik untuk memberikan kemudahan dalam mengelola berbagai macam data akademik secara terintegrasi serta memberikan layanan yang lebih baik kepada siswanya. Sebuah model architecture enterprise Sistem Informasi Akademik dibutuhkan agar meminimalisir kegagalan ketika menerapkan sistem tersebut sekaligus dapat berjalan sesuai kebutuhan di SMA PL Don Bosko Semarang. Metode analisis dalam penelitian ini menggunakan Framework Zachman yang memberikan pondasi dalam membantu menyediakan struktur dasar organisasi sehingga dapat mendukung perancangan dan pengembangan sistem informasi suatu organisasi. Hasil dari penelitian ini berupa blueprint (cetak biru pemodelan Sistem Informasi Akademik. Kata kunci— sistem informasi akademik, architecture enterprise, framework zachman, bluprint

  4. Don Quixote and Roque Guinart against the way of life of the influential people

    Directory of Open Access Journals (Sweden)

    Isabel M. Roger

    2016-11-01

    Full Text Available The apocryphal Second part of don Quixote altered many of the purposes of Cervantes. He changed the destination of his hero. As observed by don Quixote when visiting a printinghouse, its publication took place in Barcelona. The author gave prominence to a town as in picaresque novels. However, he did not modify his attitude towards the behaviour of the influential people, in keeping with Erasmus’ concept of stupidity. Surely, Cervantes reaffirmed his approach to the golden age through the presence of Roque Guinart, the only historical character who appears in the novel. This paper examines how the influential people behave in front of don Quixote, and how his performance is similar to that of Roque Guinart.

  5. The creator of the term 'anancasm' was Hungarian: Guyla Donáth (1849-1944).

    Science.gov (United States)

    Steinberg, Holger

    2015-12-01

    There is considerable confusion in the field of research on the history of psychiatry as to who created the term anancasm. This article seeks to clarify that the term was coined by the Hungarian psychiatrist Gyula Donáth, who was born in Baja, on the Danube, and worked mainly in Budapest. Donáth's publications reveal that his predominant sphere of interest and research was neurology and psychiatry. A number of his publications deal with epilepsy and obsessive-compulsive disorders. After a period of intensive research, during which he spent some time in Berlin at the clinic of neuroscientist Carl Westphal, Donáth proposed the term 'anancasm' in 1895 to describe compulsive mental processes. © The Author(s) 2015.

  6. Co-Contamination of DON and NIV in Domestic Flour in Japan: Survey, Intake, Reduction and Rapid Assay

    Science.gov (United States)

    Nivalenol (NIV) and Deoxynivalenol (DON) are trichothecene mycotoxins produced by Fusarium spp. that contaminate mainly cereal crops, such as wheat, barley, and maize. These mycotoxins are serious health hazards to humans and domestic animals. In Japan, there have been many reports of DON and NIV ...

  7. Evaluation of genetic toxicity of 6-diazo-5-oxo-l-norleucine (DON).

    Science.gov (United States)

    Kulkarni, Rohan M; Dakoulas, Emily W; Miller, Ken E; Terse, Pramod S

    2017-09-01

    DON (6-diazo-5-oxo-l-norleucine), a glutamine antagonist, was demonstrated to exhibit analgesic, antibacterial, antiviral and anticancer properties. The study was performed to characterize its in vitro and in vivo genetic toxicity potential. DON was tested in the bacterial reverse mutation assay (Ames test) using Salmonella typhimurium tester strains (TA98, TA100, TA1535 and TA1537) and Escherichia coli tester strain (WP2 uvrA) with and without S9 and also with reductive S9. In addition, DON was tested for the chromosome aberrations in Chinese hamster ovary (CHO) cells with or without S9 to evaluate the clastogenic potential. Furthermore, DON was also evaluated for its in vivo clastogenic activity by detecting micronuclei in polychromatic erythrocyte (PCE) cells in bone marrow collected from the male mice dosed intravenously with 500, 100, 10, 1 and 0.1 mg/kg at 24 and 48-h post-dose. The Ames mutagenicity assay showed no positive mutagenic responses. However, the in vitro chromosome aberration assay demonstrated dose dependent statistically positive increase in structural aberrations at 4 and 20-h exposure without S9 and also at 4-h exposure with S9. The in vivo micronucleus assay also revealed a statistically positive response for micronucleus formation at 500, 100 and 10 mg/kg at 24 and 48-h post-dose. Thus, DON appears to be negative in the Ames test but positive in the in vitro chromosome aberration assay and in the in vivo micronucleus assay. In conclusion, the results indicate DON is a genotoxic compound with a plausible epigenetic mechanism.

  8. RICKETS AT THE MEDICI COURT OF FLORENCE: THE CASE OF DON FILIPPINO (1577-1582).

    Science.gov (United States)

    Castagna, Maura; Giuffra, Valentina; Fattori, Silvia; Vitiello, Angelica; Caramella, Davide; Giustini, Davide; Fornaciari, Gino

    2014-01-01

    Among the children found in the crypt of the Grand Duke Giangastone in S. Lorenzo Basilica (Florence), the skeletal remains of a 5-year-old child still wearing his fine high social status clothing were recovered. This child of the Medici family was identified as Don Filippino (1577-1582), son of the Grand Duke Francesco I (1541-1587) and Giovanna from Austria (1547 - 1578). The prince showed several pathological deformities of the cranial and post-cranial skeleton, including enlargement of the cranium, thinning of the cranial vault bones (craniotabes), platybasia and marked bending of femora, tibiae and fibulae. Differential diagnosis suggests that Don Filippino was affected by rickets. The occurrence of this metabolic disease related to vitamin D deficiency in a Renaissance high social class individual can be explained by the practice of very prolonged breast-feeding, up until two years of age. Maternal milk contains insufficient vitamin D ratios and retarded weaning severely exposes children to a higher risk of developing rickets, especially if dietary habits are combined with inadequate exposure to sunlight. Historical sources describe Don Filippino as frail and sickly, with frequent illnesses and persistent slight fevers, and it can be supposed that the child was frequently confined indoors, especially in the cold season. Integration of osteoarchaeological evidence with historical documentation suggests that bone lesions observed in the skeletal remains of Don Filippino are compatible with a diagnosis of rickets, caused by the custom of prolonged breast-feeding associated with inadequate sunlight exposure to sunlight. Historical sources describe Don Filippino as frail and sickly, with frequent illnesses and persistent slight fevers, and it can be supposed that the child was frequently confined indoors, especially in the cold season. Integration of osteoarchaeological evidence with historical documentation suggests that bone lesions observed in the skeletal

  9. Organ Damage and Hepatic Lipid Accumulation in Carp (Cyprinus carpio L. after Feed-Borne Exposure to the Mycotoxin, Deoxynivalenol (DON

    Directory of Open Access Journals (Sweden)

    Constanze Pietsch

    2014-02-01

    Full Text Available Deoxynivalenol (DON frequently contaminates animal feed, including fish feed used in aquaculture. This study intends to further investigate the effects of DON on carp (Cyprinus carpio L. at concentrations representative for commercial fish feeds. Experimental feeding with 352, 619 or 953 μg DON kg−1 feed resulted in unaltered growth performance of fish during six weeks of experimentation, but increased lipid peroxidation was observed in liver, head kidney and spleen after feeding of fish with the highest DON concentration. These effects of DON were mostly reversible by two weeks of feeding the uncontaminated control diet. Histopathological scoring revealed increased liver damage in DON-treated fish, which persisted even after the recovery phase. At the highest DON concentration, significantly more fat, and consequently, increased energy content, was found in whole fish body homogenates. This suggests that DON affects nutrient metabolism in carp. Changes of lactate dehydrogenase (LDH activity in kidneys and muscle and high lactate levels in serum indicate an effect of DON on anaerobic metabolism. Serum albumin was reduced by feeding the medium and a high dosage of DON, probably due to the ribotoxic action of DON. Thus, the present study provides evidence of the effects of DON on liver function and metabolism.

  10. Organ Damage and Hepatic Lipid Accumulation in Carp (Cyprinus carpio L.) after Feed-Borne Exposure to the Mycotoxin, Deoxynivalenol (DON)

    Science.gov (United States)

    Pietsch, Constanze; Schulz, Carsten; Rovira, Pere; Kloas, Werner; Burkhardt-Holm, Patricia

    2014-01-01

    Deoxynivalenol (DON) frequently contaminates animal feed, including fish feed used in aquaculture. This study intends to further investigate the effects of DON on carp (Cyprinus carpio L.) at concentrations representative for commercial fish feeds. Experimental feeding with 352, 619 or 953 μg DON kg−1 feed resulted in unaltered growth performance of fish during six weeks of experimentation, but increased lipid peroxidation was observed in liver, head kidney and spleen after feeding of fish with the highest DON concentration. These effects of DON were mostly reversible by two weeks of feeding the uncontaminated control diet. Histopathological scoring revealed increased liver damage in DON-treated fish, which persisted even after the recovery phase. At the highest DON concentration, significantly more fat, and consequently, increased energy content, was found in whole fish body homogenates. This suggests that DON affects nutrient metabolism in carp. Changes of lactate dehydrogenase (LDH) activity in kidneys and muscle and high lactate levels in serum indicate an effect of DON on anaerobic metabolism. Serum albumin was reduced by feeding the medium and a high dosage of DON, probably due to the ribotoxic action of DON. Thus, the present study provides evidence of the effects of DON on liver function and metabolism. PMID:24566729

  11. La reciprocidad y el don no son la misma cosa

    Directory of Open Access Journals (Sweden)

    Ricardo Gabriel Abduca

    2007-12-01

    Full Text Available El autor se propone mostrar por qué la noción de reciprocidad, aunque ha sido muchas veces tomada como sinónimo del fenómeno de intercambios de dones, corresponde a diversas situaciones sociales, por lo cual tiene poca utilidad descriptiva y explicativa. Examina algunos hitos de la historia antropológica, mostrando que más que un concepto, 'reciprocidad' es un palimpsesto sobre el cual, de Durkheim a Polanyi, se han ido escribiendo variadas nociones. En cambio, sugiere una definición de don más estricta, cercana a las ideas de Mauss y acorde con los avances de la etnografía y la teoría contemporánea. Sugiere distinguir entre circuitos cerrados de dones, donde circulan bienes de consumo final, y circuitos abiertos, donde los dones que circulan condensan el conjunto de las relaciones sociales.O objetivo deste texto é mostrar que a expressão 'reciprocidade', ainda foi considerada como sinônimo de 'câmbio de domes', é outra coisa. O autor sugere um breve esquema de alguns marcos do desenvolvimento da noção de 'reciprocidade' em a teoria antropológica, mostrando que o sentido dela expressão foi mudando até assemelhar um palimpsesto com múltiplas rescritas, no processo que vá de Durkheim a Polanyi. Defende um conceito de dom próximo às idéias de Mauss e a certos avances dela etnografia contemporânea e a teoria social. Distingue deus tipos de circuitos de circulação de domes: fechados, onde circulam bens de consumação direita, e apertos, onde circulam certo tipo de bens que condensam o conjunto das relações sociais.The aim of this text is to show how the notion of 'reciprocity', although have been considered a synonymous of gift exchange, veils different social situations. A brief survey of the history of the use of the word shows how 'reciprocity', from Durkheim to Polanyi, seems as a palimpsest of various notions. Although, he essays a defense of a concept of 'gift' related to the Maussian texts, and closer to some

  12. Un curioso coleccionista del siglo XVII: don Manuel de Porras

    Directory of Open Access Journals (Sweden)

    Agulló y Cobo, Mercedes

    2003-09-01

    Full Text Available Art collecting - an avocation almost exclusive to royalty in Spain - has not had representatives among those who did not belong to the high nobility, not even among artists themselves. In many cases, the word "collection" has been applied to what in reality were mere lists of patrimonial properties. For all of the above, it is especially noteworthy to encounter someone who neither belonged to an elevated class nor was a painter, but who managed to unite, at great personal sacrifice, an important art collection. Manuel de Porras owned interesting and a relatively large number of paintings, sculptures and prints, some of them extremely valuable. As a good collector, in order to avoid the dispersion of these works, he donated them to the Shod Trinitarians in Madrid and the Oratory of Saint Philip Neri in Alcalá, but unfortunately, in spite of his good intentions, nothing has survived.

    El coleccionismo —afición casi exclusiva de Reyes en España— no ha tenido representantes entre personas que no pertenecieran a la alta nobleza, ni entre los propios artistas. En muchos casos lo que se ha venido llamando colecciones son sólo relación de bienes patrimoniales. Por ello, resulta más llamativo encontrar alguien que, sin pertenecer a una clase elevada ni ser artista, lograra reunir —aun a costa de grandes sacrificios que le llevaron al extremo de ser enterrado de limosna— una tan importante colección de obras de arte como el personaje objeto de este artículo: Manuel de Porras, quien contaba con un interesante y elevado (para un particular sin títulos número de pinturas y esculturas, y un importantísimo número de dibujos y estampas, algunas valiosísimas y de alto precio. Desgraciadamente, aunque lo donó —como buen coleccionista, para evitar su dispersión— a los Trinitarios calzados de Madrid y al Oratorio de San Felipe Neri de Alcalá, nada de ello ha llegado a nuestros días.

  13. The I Don't Know Option in the Vocabulary Size Test

    Science.gov (United States)

    Zhang, Xian

    2013-01-01

    The current study evaluates guessing behaviors in a vocabulary size test (VST) and examines whether including an "I don't know" in a VST may have an impact on the results of the test. One-hundred-fifty first-year students at a university in China took part in the study. They were randomly assigned to three groups. Each group took a…

  14. 77 FR 21556 - Don Pedro Hydroelectric Project: Turlock Irrigation District; Modesto Irrigation District...

    Science.gov (United States)

    2012-04-10

    .... Date and Time of Meeting: Tuesday, April 17, 2012. 9 a.m.-5 p.m. b. Place: Holiday Inn, Sacramento-Capitol Plaza, 300 J Street, Sacramento, CA 95814, 916-446-0100. c. FERC Contact: Stephen Bowler, Don... technical conference would be an all day meeting in Sacramento, California on April 17, 2012. The notice...

  15. Tiffany Diamonds and Classical Music as Influences on the Performance of "Don Juan in Hell".

    Science.gov (United States)

    Johnson, Jim

    This paper analyzes Paul Gregory's 1951 production of "Don Juan in Hell," now considered to be a seminal work in the development of professional and educational readers theatre. The paper contends that the production, which presented a nondramatic work without the usual emphasis on design and spectacle, forced a reexamination of the role…

  16. Spendere meno, spendere meglio: una proposta panottica di J.-C. Guédon

    Directory of Open Access Journals (Sweden)

    Maria Chiara Pievatolo

    2013-06-01

    Full Text Available J.-C. Guédon ha commentato la nostra campagna di crowdsourcing in merito alle spese delle biblioteche sulla mailing list Nexa. Offriamo, qui di seguito, la versione italiana delle sue osservazioni – che presuppongono un mondo accademico molto diverso da quello impostoci...

  17. Dr. S. Donald (Don) Stookey (1915-2014): Pioneering Researcher and Adventurer

    Science.gov (United States)

    Beall, George H.

    2016-07-01

    Don Stookey, the father of glass-ceramics, was a pioneer in inducing and understanding internal nucleation phenomena in glass. His early work on dense opal glasses and photosensitive precipitation of gold and silver in glass led to an amazing series of inventions: Fotalite, a photosensitive opal, chemically machined Fotoform and Fotoceram, and TiO2-nucleated Pyroceram products including missile nosecones and oven-proof cookware. He received a basic patent on glass-ceramics, which was contested and affirmed in court. Don was able to demonstrate a clear photochromic glass that showed reversible darkening for thousands of cycles. This material became a fixture in the ophthalmic industry. He went on to invent a full-color polychromatic glass, capable of yielding a permanent patterned and monolithic stained glass. In his life outside science, Don chaired an interfaith group that founded a home for the elderly in Corning. He was also a wilderness enthusiast, surviving a plane crash in the Arctic and two boat capsizings. Even in his later years, he continued fishing off the coast of Florida and on Lake Ontario and went solo on a trip to the Patagonian Andes. Don Stookey was a special person by any measure: an unassuming optimist, eminent scientist and inventor, adventurer, and a beloved family man. Introduction

  18. What Catholic Educators Can Learn from the Radical Christianity and Critical Pedagogy of Don Lorenzo Milani

    Science.gov (United States)

    Grech, Michael; Mayo, Peter

    2014-01-01

    This paper explores some of the ideas expressed in or associated with the work of Don Lorenzo Milani and the School of Barbiana and discusses them in the light of the teachings of the gospels. It draws out the implications of these ideas for a critical education in the Christian spirit. The focus throughout is on Christian education for social…

  19. Inheritance of allozyme variants in bishop pine (Pinus muricata D.Don)

    Science.gov (United States)

    Constance I. Millar

    1985-01-01

    Isozyme phenotypes are described for 45 structural loci and I modifier locus in bishop pine (Pinus muricata D. Don,) and segregation data are presented for a subset of 31 polymorphic loci from 19 enzyme systems. All polymorphic loci had alleles that segregated within single-focus Mendelian expectations, although one pair of alleles at each of three...

  20. DON JUAN: THE DISCOURSE OF SEDUCTION AS AN EXERCISE OF POWER

    Directory of Open Access Journals (Sweden)

    Kristina Stankevičiūtė

    2016-10-01

    Full Text Available The figure of Don Juan that emerged in Spanish baroque synthesised several important cultural issues related to the phenomenon of seduction, a subject of great social controversy since the very beginning of the Christian era. The present article analyses one of the fundamental parts of the universal appeal of the Don Juan figure – the discourse of seduction, considering it from the social and cultural point of view. The traditional discussion of the subject focuses on the contents of the discourse whereas the present article emphasises the implications rather than the contents, grounding its arguments on Jean Baudrillard’s theory of seduction, which claims that it is the signs and the play of signs that are important in seduction, not their meanings. The seduction discourse is seen as a means to exercise power on the women that Don Juan deals with as well as on the audience who gets involved into the discourse creation process. The article concludes with a claim that Don Juan is a figure of social domination, and his discourse is a means to achieve it.

  1. Why I don't kill myself : [poems] / Paul-Eerik Rummo

    Index Scriptorium Estoniae

    Rummo, Paul-Eerik, 1942-

    2003-01-01

    Autori lühitutvustus lk. 262. Sisu: Why I don't kill myself ; The sky stoops over the earth ; Clinging ; Crooning. Orig.: Miks ma end ära ei tapa ; "Taevas on kummargil üle maa..." ; Kinni hoidmas ; Poolüminal

  2. Dr. S. Donald (Don Stookey: (1915-2014: Pioneering Researcher and Adventurer

    Directory of Open Access Journals (Sweden)

    George Halsey Beall

    2016-08-01

    Full Text Available Don Stookey was a special person by any measure: an unassuming optimist, eminent scientist and inventor, adventurer, and a beloved family man. Don Stookey, the father of glass-ceramics, was a pioneer in inducing and understanding internal nucleation phenomena in glass. His early work on dense opal glasses and photosensitive precipitation of gold and silver in glass led to an amazing series of inventions: Fotalite®, a photosensitive opal, chemically machined Fotoform® and Fotoceram®, and TiO2-nucleated Pyroceram™ products including missile nosecones and oven-proof cookware. He received a basic patent on glass-ceramics which was contested and affirmed in court.Don was able to demonstrate a clear photochromic glass that showed reversible darkening for thousands of cycles. This material became a fixture in the ophthalmic industry. He went on to invent a full-color polychromatic glass capable of yielding a permanent patterned and monolithic stained glass.In his life outside science, Don chaired an interfaith group that founded a home for the elderly in Corning. He was also a wilderness enthusiast, surviving a plane crash in the Arctic and two boat capsizings. Even In his later years, he continued fishing off the coast of Florida and on Lake Ontario, and went solo on a trip to the Patagonian Andes.

  3. Birds of a Feather Don't Always Flock Together : User Problems in ...

    African Journals Online (AJOL)

    Birds of a Feather Don't Always Flock Together : User Problems in Identifying ... for Advanced Learners and Oxford Advanced Learner's Dictionary) revealed a lack ... This paper is based on 14 of these phrasemes, which appear in one or more of ... Five strategies are presented to help learners with their dictionary searches.

  4. Il don giovanni tenorio di carlo goldoni. Alle origini di un mito moderno

    African Journals Online (AJOL)

    By transforming the protagonist's religious impiety into sexual incontinence, Goldoni draws a link between Molière's drama (1665) and the version set to music by Mozart in 1787. An analysis of the text with a focus on the reception and adaptation by Goldoni of the early plays reveals the centrality of his Don Giovanni in the ...

  5. "Boys Don't Cry," a Movie Review: Implications for Counseling Persons Who Are Transgendered

    Science.gov (United States)

    Aguilar, Jinnelle Veronique

    2010-01-01

    People who fall under the umbrella of transgender belong to one of the most marginalized groups within society. Many who do not pass within the gender binary categories imposed by social norms experience discrimination and marginalization. In this article, the author discusses the film "Boys Don't Cry" and introduces the reader to the varieties of…

  6. The E-learning Cabaret: do's and don'ts in E-Learning Design

    NARCIS (Netherlands)

    Westera, Wim

    2009-01-01

    Westera, W. (2006). The E-Learning Cabaret: do's and don'ts in E-Learning Design. Book of Abstracts, 12th International Conference on Technology Supported Learning & Teaching, Online Educa Berlin (pp. 169-171). November, 29-December, 1, 2006, Berlin, Germany: ICWE-GmbH.

  7. What We Don't Understand, We Explain to Each Other

    Science.gov (United States)

    Pines, David

    2015-01-01

    "What we don't understand, we explain to each other" was Robert Oppenheimer's 1948 description of theoretical physics as a profession. Because the phrase connects research, teaching, and learning, it seemed the right approach for the talk I gave to the AAPT [American Association of Physics Teachers] on receiving the 2013 J.D. Jackson…

  8. Transient identification system with noising data and 'don't know' response

    International Nuclear Information System (INIS)

    Mol, Antonio C. de A.; Martinez, Aquilino S.; Schirru, Roberto

    2002-01-01

    In the last years, many different approaches based on neural network (NN) has been proposed for transient identification in nuclear power plants (NPP). Some of them focus the dynamic identification using recurrent neural networks however, they are not able to deal with unrecognized transients. Other kind of solution uses competitive learning in order to allow the 'don't know' response. In this case dynamic, dynamic features are not well represented. This work presents a new approach for neural network based transient identification which allows either dynamic identification and 'don't know'response. Such approach uses two multilayer neural networks trained with backpropagation algorithm. The first one is responsible for the dynamic identification. This NN uses, a short set (in a movable time window) of recent measurements of each variable avoiding the necessity of using starting events. The other one is used to validate the instantaneous identification (from the first net) through the validation of each variable. This net is responsible for allowing the system to provide 'don't know' response. In order to validate the method a NPP transient identification problem comprising 15 postulated accidents, simulated for a pressurized water reactor, was proposed in the validation process it has been considered noising data in other to evaluate the method robustness. Obtained results reveal the ability of the method in dealing with both dynamic identification of transients and correct 'don't know' response. In order to validate the method, a NPP transient identification problem comprising 15 postulated accidents simulated for a pressurized water reactor, was proposed in the validation process it has been considered noising data in order to evaluate the method robustness. Obtained results reveal the ability of the method in dealing with both dynamic identification of transients and correct 'don't know' response. (author)

  9. Study of the use of a micro hydro in knockdown container completed with a cylindrical form housing of francis hydraulic turbine to support the development program of energy self-sustainability for remote and isolated areas in Indonesia

    Directory of Open Access Journals (Sweden)

    Kamal Samsul

    2017-01-01

    It shows that the implementation of the unit in a remote area has reduced the total site construction time by 1/3 compared to the predicted one with conventional unit. The performance of the Francis turbine with cylindrical form housing has shown comparable with the conventional one which has volute form housing. The superiority was even more pronounced by introducing a deflection insert in its input flow channel. The insertion was capable to create more distributed flow into the runner. Efficiency of the turbine up to 80% was performed in this research. Local manufacture for turbine usually use many craft work and welding to built a volute form housing for the Francis turbine. The cylindrical form housing here has also proven significantly in reducing the time and price for the turbine manufacturing process.

  10. Toward an epistemology of nano-technosciences: Probing technoscience from a historical perspective: on today's surprising prevalence and relevance of Francis Bacon.

    Science.gov (United States)

    Schmidt, Jan C

    2011-12-01

    This paper aims to contribute to the attempts to clarify and classify the vague notion of "technosciences" from a historical perspective. A key question that is raised is as follows: Does Francis Bacon, one of the founding fathers of the modern age, provide a hitherto largely undiscovered programmatic position, which might facilitate a more profound understanding of technosciences? The paper argues that nearly everything we need today for an ontologically well-informed epistemology of technoscience can be found in the works of Bacon-this position will be called epistemological real-constructivism. Rather than realist or constructivist, empiricist or rationalist, Bacon's position can best be understood as real-constructivist since it challenges modern dichotomies. Reflection upon the contemporary relevance of Bacon could contribute to the expanding and critical discussion on technoscience. In the following I will reconstruct the term "technoscience". My finding is that at least four different understandings or types of the term "technoscience" co-exist. In a second step, I will analyze and elaborate on Bacon's epistemological position. I will identify central elements of the four different understandings in Bacon's work. Finally, I will conclude that the epistemology of technoscience is, indeed, very old-it is the epistemological position put forward by Bacon.

  11. Gossip; Gift and Commodity in Francis Coventry’s History of Pompey the Little; or; The Life and Adventures of a Lap-Dog (1751

    Directory of Open Access Journals (Sweden)

    Ana Vogrinčič

    2007-06-01

    Full Text Available Francis Coventry’s History of Pompey the Little represents one of the better known examples of today otherwise neglected eighteenth-century English novels of non human-characters. By pointing at thus far unacknowledged dimensions of the text; the article challenges the established reading of the book as put forward by Liz Bellamy in the theory of the ‘novels of circulation’. According to Bellamy; the peregrinating animals and objects of these narratives represent circulating commodities and thus symbolize alienated commercial society. Demonstrating that Pompey the lapdog rather functions as a gift and a gossip; this essay offers an alternative interpretation which opens up a different perspective on Coventry’s representation of society. Following from this; the paper aims at situating Pompey the Little’ within broader socio-cultural context of eighteenth-century England; as well as reflects on its place in fiction of the period. As such it advocates socio-historical approaches to literature.

  12. A Portrait of the Rebel as an Artist: Deconstructing Post-coloniality in Francis Stuart’s Black List, Section H

    Directory of Open Access Journals (Sweden)

    Shahriyar Mansouri

    2016-03-01

    Full Text Available The historically ‘interrogative’ nature of the modern Irish novel introduces post-independence Ireland as a locus that is torn between social double standards and political extremes. Rebellious and critical voices channelled through the dialectical discourse of the novel and at once critiqued a State-sponsored voice of internal othering and narratives of decolonization. To sustain its relevance as a medium of criticism the modern Irish novel replaced the classical structure of the novel with narratives that tend to deconstruct the State’s politics of formation. These narratives, this paper suggests, are inherently personal and structurally biographical, enabling the Irish to revisit the past and restructure their perception of critical concepts such as national identity, ideological intolerance, and individual formation. By examining Francis Stuart’s Black List, Section H (1971, and John McGahern’s The Dark (1965, firstly I will identify these resistant voices, which challenged and subverted the socio-political, and educational boundaries. Secondly, I will explore a dividing line that appeared between such critical voices, splitting them into critics who sought a liberated definition of Irishness rooted in the principles of the men of 1916, and rebels who demanded social recognition and political and commercial success. It is the latter group, I argue, that instead of enhancing the standards of life in Ireland became a threat to its very foundation.

  13. Model and prototype investigations of upper partial load unsteady phenomena on the Francis turbine designed for head up to 120 m

    International Nuclear Information System (INIS)

    Power Machines - LMZ, Saint-Petersburg, str. Vatutina 3A (Russian Federation))" data-affiliation=" (OJSC Power Machines - LMZ, Saint-Petersburg, str. Vatutina 3A (Russian Federation))" >Kuznetsov, I; Power Machines - LMZ, Saint-Petersburg, str. Vatutina 3A (Russian Federation))" data-affiliation=" (OJSC Power Machines - LMZ, Saint-Petersburg, str. Vatutina 3A (Russian Federation))" >Zakharov, A; Power Machines - LMZ, Saint-Petersburg, str. Vatutina 3A (Russian Federation))" data-affiliation=" (OJSC Power Machines - LMZ, Saint-Petersburg, str. Vatutina 3A (Russian Federation))" >Arm, V; Power Machines - LMZ, Saint-Petersburg, str. Vatutina 3A (Russian Federation))" data-affiliation=" (OJSC Power Machines - LMZ, Saint-Petersburg, str. Vatutina 3A (Russian Federation))" >Akulaev, R

    2014-01-01

    The upper partial load unsteady phenomena are often observed at model tests for Francis turbine with high and middle specific speed. It is appears approximately between 7085% of optima point discharge for constant unit speed value and has accompanied by additional phenomenon with much higher frequency than draft tube vortex precession frequency and also runner rotational frequency. There are some discussions about nature of this phenomena and transposition of unsteady model test results to the prototype. In this paper are presented the results of above mentioned phenomena model investigations and some results of investigation at prototype turbine. Based on the results of model tests the following extensive data have been obtained: pressure fluctuation in the draft tube cone and spiral case, axial force fluctuations, it is demonstrated the significant influence of cavitation on upper partial load unsteady phenomena. The result of measurements of bearing vibrations and pressure pulsations are presented for prototype turbine at corresponded or very close operation points to model. In accordance with obtained data it is demonstrated that at upper partial load operation the unsteady phenomenon is observed as for the model also for the prototype turbine. On the base of model investigation has been demonstrated the influence of air admission and special design solutions to diminish unsteady phenomena at upper partial load range. All investigations were based on the physical experiment. Thus, based on model and prototype experimental investigations it is obtained additional information about upper partial load unsteady phenomenon and confirmed the transposition of model results to prototype turbine

  14. Characterization of Fish Passage Conditions through a Francis Turbine, Spillway, and Regulating Outlet at Detroit Dam, Oregon, Using Sensor Fish, 2009

    Energy Technology Data Exchange (ETDEWEB)

    Duncan, Joanne P.; Carlson, Thomas J.

    2011-05-06

    Fish passage conditions through two spillways, a Francis turbine, and a regulating outlet (RO) at Detroit Dam on the North Santiam River in Oregon were evaluated by Pacific Northwest National Laboratory for the U.S. Army Corps of Engineers (USACE), Portland District, using Sensor Fish devices. The objective of the study was to describe and compare passage exposure conditions, identifying potential fish injury regions within the routes. The study was performed in July, October, and December 2009 concurrent with HI-Z balloon-tag studies by Normandeau Associates, Inc. Sensor Fish data were analyzed to estimate 1) exposure conditions, particularly exposure to severe strike, collision, and shear events by passage route sub-regions; 2) differences in passage conditions between passage routes; and 3) relationships to live-fish injury and mortality data estimates. Comparison of the three passage routes evaluated at Detroit Dam indicates that the RO passage route through the 5-ft gate opening was relatively the safest route for fish passage under the operating conditions tested; turbine passage was the most deleterious. These observations were supported also by the survival and malady estimates obtained from live-fish testing. Injury rates were highest for turbine and spillway passage. However, none of the passage routes tested is safe for juvenile salmonid passage.

  15. Sloshing motion dynamics of a free surface in the draft tube cone of a Francis turbine operating in synchronous condenser mode

    Science.gov (United States)

    Vagnoni, Elena; Andolfatto, Loïc; Favrel, Arthur; Avellan, François

    2016-11-01

    The penetration of the electrical grid by intermittent renewable energy sources induces grid fluctuations which must be compensated in order to guarantee the stability of the grid. Hydropower plants can supply reactive power to ensure the grid stabilization by operating in condenser mode. In this operating mode, the turbine operates with the tail water depressed to let the runner spin in air to reduce the power consumption. Pressurized air is injected in the draft tube cone to maintain the water level below the runner and this induces air-water interaction phenomena which cause important power losses. Flow visualization and pressure fluctuation measurements are performed in a reduced scale physical model of a Francis turbine operating in condenser mode to investigate the dynamics of the air-water interaction in the draft tube cone which causes the sloshing motion of the free surface. An image post-processing method is developed, enabling a quantitative description of the sloshing motion. The latter depends on the Froude number. By increasing the value of the Froude number, the amplitude of the sloshing motion decreases, as well as the amplitude of the pressure fluctuations. The frequency of the sloshing motion corresponds to the first natural frequency of the water volume.

  16. L’utilité de la théorie du don The utility of gift theory Utilidad de la teoría del don

    Directory of Open Access Journals (Sweden)

    Norbert Alter

    2012-12-01

    Full Text Available Norbert Alter explique l’utilité et l’actualité de la théorie de Marcel Mauss pour penser la coopération en entreprise et l’engagement au travail. Il revient sur ses qualités heuristiques et sa portée critique nécessaires à mobiliser pour donner des clefs de compréhension et d’action au monde du travail. À cette contribution répond celle d’Alain Caillé, « Le paradigme du don face aux nouvelles réalités du monde du travail. Quelques remarques »Norbert Alter explains here the utility and topicality of Marcel Mauss’ theory in an analysis touching both on cooperation within a business structure and on people’s commitment to work. He reviews the heuristic qualities and critical scope that must be mobilised to create ways of understanding and acting within the work world. Alain Caillé responds to this contribution with his own article entitled, “ The gift paradigm facing new realities in the work world. Comments” (Le paradigme du don face aux nouvelles réalités du monde du travail. Quelques remarques.Norbert Alter explica la utilidad y la actualidad de la teoría de Marcel Mauss para pensar la cooperación en la empresa y el compromiso en el trabajo. Desde una nueva perspectiva, aborda las cualidades heurísticas de esa teoría y su alcance crítico, que es necesario movilizar para contar con claves de comprensión y de acción en el mundo laboral. A su contribución, Alain Caillé responde con el artículo “El paradigma del don frente a las nuevas realidades del mundo laboral. Algunas observaciones”.

  17. Don't Let Gun Sports Backfire on You: Use Ear Protection and Hang onto Your Hearing

    Science.gov (United States)

    ... Inside NIDCD Newsletter » Spring 2006 Don't Let Gun Sports Backfire on You: Use Ear Protection and ... in the skeet event, would never fire a gun without them. Likewise, Dave Henderson, a nationally recognized ...

  18. “I don't use a condom (with my regular partner) because I know that I ...

    African Journals Online (AJOL)

    I don't use a condom (with my regular partner) because I know that I'm faithful, but with everyone else I do”: The cultural and socioeconomic determinants of sexual partner concurrency in young South Africans.

  19. Deoxynivalenol (DON Contamination of Feed and Grinding Fineness: Are There Interactive Implications on Stomach Integrity and Health of Piglets?

    Directory of Open Access Journals (Sweden)

    Sven Dänicke

    2017-01-01

    Full Text Available The common feed contaminant deoxynivalenol (DON was reported to influence the morphology of the pars nonglandularis (PN of porcine stomach. Moreover, finely ground feed is known to trigger the development of ulcers and other pathologies of PN while coarsely ground feed protects from such lesions. The interactions between grinding fineness and DON contamination of feed were not examined so far. Therefore, both finely and coarsely ground feeds were tested either in the absence or presence of a DON contaminated wheat on growth performance and health of rearing piglets, including stomach integrity. DON contamination significantly reduced feed intake and serum albumin concentration with this effect being more pronounced after feeding the coarsely ground feed. Albeit at a higher level, albumin concentration was also reduced after feeding the finely ground and uncontaminated feed. Finely ground and DON-contaminated feed caused a significantly more pronounced lymphoplasmacytic infiltration both of PN and pars glandularis, partly paralleled by lymph follicle formation and detritus filled foveolae and tubes suggesting a local immune response probably triggered by epithelial lesions. It is concluded that DON contamination of feed exacerbates the adverse effects of finely ground feed on stomach mucosal integrity.

  20. Deoxynivalenol (DON) Contamination of Feed and Grinding Fineness: Are There Interactive Implications on Stomach Integrity and Health of Piglets?

    Science.gov (United States)

    Dänicke, Sven; Beineke, Andreas; Berk, Andreas; Kersten, Susanne

    2017-01-01

    The common feed contaminant deoxynivalenol (DON) was reported to influence the morphology of the pars nonglandularis (PN) of porcine stomach. Moreover, finely ground feed is known to trigger the development of ulcers and other pathologies of PN while coarsely ground feed protects from such lesions. The interactions between grinding fineness and DON contamination of feed were not examined so far. Therefore, both finely and coarsely ground feeds were tested either in the absence or presence of a DON contaminated wheat on growth performance and health of rearing piglets, including stomach integrity. DON contamination significantly reduced feed intake and serum albumin concentration with this effect being more pronounced after feeding the coarsely ground feed. Albeit at a higher level, albumin concentration was also reduced after feeding the finely ground and uncontaminated feed. Finely ground and DON-contaminated feed caused a significantly more pronounced lymphoplasmacytic infiltration both of PN and pars glandularis, partly paralleled by lymph follicle formation and detritus filled foveolae and tubes suggesting a local immune response probably triggered by epithelial lesions. It is concluded that DON contamination of feed exacerbates the adverse effects of finely ground feed on stomach mucosal integrity. PMID:28045426

  1. The first theatrical adaptations of the Don Quixote and the beginning of Cervantes

    Directory of Open Access Journals (Sweden)

    Carmen Rivero Iglesias

    2012-12-01

    Full Text Available The present study analyzes the first appearances of Don Quixote on German stages. The goal is to illustrate how these theatrical performances determine the reception of Cervantes’ work in 17th century Germany. The first performances in Heidelberg (1613 and Dessau (1614 display an interpretation of Don Quixote, which intensifies the grotesque dimension of Cervantes’ original. Its satire is transformed into a satire of Spain in a context determined by political and religious animosity between Catholics and Protestants. The first German translation inherited this conception of Cervantes’ work. This conception would acquire new shades until middle of the 18th century, when the alteration of historical coordinates and the rise of individuality and genius thoroughly transformed its interpretation.

  2. Operatic films: a comparative study of Don Giovanni by Joseph Losey and Juan by Kasper Holten

    Directory of Open Access Journals (Sweden)

    Isabel VILLANUEVA BENITO

    2017-12-01

    Full Text Available From an artistic point of view, the adaptation of an opera to the cinema, traditionally has been considered a complex and controversial process. Don Giovanni, of W.A. Mozart is one of the operas that more audiovisual versions has generated during the centuries XX and XXI, although very few films have finally been taken to the screen. This paper is focused on comparing the audiovisual versions Don Giovanni, by Joseph Losey (1979, and Juan by Kasper Holten (2010. Through a quantitative and qualitative methodology based on content analysis, this research reflects on the degree of intervention exercised by the language and audiovisual format used in the process of reinterpretation of the pre-existing operatic text.

  3. ["Is it an animal inside? "Melanie Klein's unpublished Don Juan Paper (1939)].

    Science.gov (United States)

    Frank, Claudia

    2008-01-01

    Klein had been asked to contribute an article to the birthday number of the International Journal for Jones. The author outlines how she hurriedly wrote a text about Don Juan which, however, was rejected by the editor. Essential parts of it are presented in German translation. The manuscript is discussed in the context of Klein's published work as well as of the relevant contemporary literature. In Klein's view, Don Juan's genitality is determined by oral impulses and fears. By his manic acting out he attempts to ward off a depressive break-down. The paper ends with some reflections about why Klein--ontrary to her intention--failed to revise her manuscript for later publication.

  4. Don Quijote, doña Rodríguez y los duques

    Directory of Open Access Journals (Sweden)

    Stanislav Zimic

    1997-12-01

    Full Text Available Al llegar Don Quijote al palacio de los duques y "viéndose tratar del mesmo modo que él había leído se trataban Ios tales caballeros en Ios pasados siglos ... , aquél fue el primer día que de todo en todo conoció y creyó ser caballero andante verdadero y no fantastíco" (1378. Comprensiblemente, esta afirmacion ha causado gran perplejidad entre los lectores de todas las épocas: "Luego, antes ¿no lo había creído?" . La cuestión se complica mucho más, poco después de estos eufóricos momentos, al confesar Don Quijote a la duquesa: "Dios sabe si hay Dulcinea o no en el mundo, o si es fantástica ono es fantástica ...

  5. Detection of calmodulin binding protein at 170 KDA in BALB, AKR, DON and chicken granulosa cells

    International Nuclear Information System (INIS)

    Selinfreund, R.; Lin, P.H.; Marrone, B.; Wharton, W.

    1987-01-01

    Calmodulin (CAM) has been shown to bind to the epidermal growth factor (EGF) receptor (170 kDa) and is phosphorylated in a EGF dependent manner in the A431 human epidermoid carcinoma cells. In the present study, they report 125 I-CAM binding to a 170 kDa protein detected in cell membrane vesicles of Balb/3T3, AKR, DON and chicken granulosa cells. Purified plasma membranes from these cells were resolved via electrophoresis (without heat denaturation) and electroblotted onto nictrocellulose paper. Upon hybridizing against 125 I-CAM, a distinct autoradiographic band occurred at 170 kDa for all the cells lines under study. The binding of CAM is specific and can be displaced with the addition of excess unlabeled CAM. The result suggest that 125 I-CAM may bind to the 170 kDa EGF receptor in BALB, AKR, DON and chicken granulosa cells

  6. Bauhinia Pottsii G. Don Var Pottsii, Koleksi Dari Kalimantan Yang Ditemukan Kembali

    OpenAIRE

    Astuti, Inggit Puji; Magandhi, Mahat; Suratman, Maman; Maulida, Risa

    2012-01-01

    Bauhinia is one of the largest genus in Caesalpiniaceae family and distributed in all tropical area. One among 300 species of Bauhinia is Bauhinia pottsii G. Don. This species is distributed from Southern Myanmar, Thailand, Cambodia, Malay Peninsular, Borneo, Sumatra, Jawa, Bali and Lesser Sunda islands. It was recorded that one specimen was originated from East Kalimantan and collected in 1925. During exploration in Kampung Temula, Kecamatan Nyuatan, Kabupaten Kutai Barat, East Kalimantan,...

  7. Mujeres españolas de la conquista en don Joan de Castellanos (I

    Directory of Open Access Journals (Sweden)

    Mario Germán Romero

    1962-10-01

    Full Text Available La participación de la mujer española en la conquista de América es un tema que apenas comienza a ser tratado con la profundidad que merece. A principios del siglo don Cesáreo Fernández Duro publicó una breve disertación sobre ' 'La mujer española en Indias".

  8. Punctuation in the text of the Golden Age and in Don Quijote

    Directory of Open Access Journals (Sweden)

    Ignacio Arellano

    2010-12-01

    Full Text Available This article examines the punctuation in Golden Age texts, in particular in Don Quixote. The author analyzes the discrepancies between theory and practice of the printers, the features of the punctuation in manuscripts, and the absence of a general system, due in part to the absence of a unique and precise system in Spanish. The article provides numerous examples of Golden Age text and of the Quixote.

  9. Department of the Navy (DON) Additive Manufacturing (AM) Implementation Plan V2.0 (2017)

    Science.gov (United States)

    2017-05-04

    aligned to advance AM of explosives, propellants, pyrotechnics and structures.  Makerspaces deployed throughout the warfighter and civilian communities...to conduct broad AM familiarization training and STEM activities 2. Introduce new makerspaces into DON to expand access and education of AM...technologies 3. Ensure makerspaces become a vital part of workforce training by developing communication plan to inform leadership of current and future

  10. Hedyotis pinifolia Wall. ex G. Don (Rubiaceae, a New Record to the Flora of Taiwan

    Directory of Open Access Journals (Sweden)

    Shih-Huei Chen

    2010-03-01

    Full Text Available Hedyotis pinifolia Wall. ex G. Don, a species of Rubiaceae, was found recently in Taiwan. It represents a new record for the flora of Taiwan, and a range extension of the species to the northeast. The present study provides the species description, illustrations, and SEM micrographs of seeds and pollen grains. Furthermore, a comparison of diagnostic characters between this species and a related species, H. tenelliflora Bl. is made.

  11. Detsibill : Meie Mees kui ANTI. White Label : Don Erikson. Kuula / DJ Pickney Tiger

    Index Scriptorium Estoniae

    DJ Pickney Tiger, pseud., 1970-

    2006-01-01

    Heliplaatidest: Don Erikson "Israel Mix", Congotronics 2 "Buzz'n'rumble from the urb'n'jungle", Critikal "Chapter One ehk Teine maitse", Nirvana "Silver, The best of the Box", Singer Vinger "Eesti Kullafond", Bullet Train To Vegas "We Put Scissors Where Our Mouths Are", Ludachris "Disturbing tha peace", "Soul Satisfaction 5", The Kurt Webber's Pink Band "Café Regatt", Patrizio Buanne "The Italian", Eminem "Curtain Call"

  12. Los centenarios: El bibliotecario don Manuel del Socorro Rodríguez

    Directory of Open Access Journals (Sweden)

    Boletín Cultural y Bibliográfico Banco de la República

    1958-04-01

    Full Text Available Se cumplió en este mes de abril el segundo centenario del nacimiento de don Manuel del Socorro Rodríguez. Con tal motivo, su memoria fue honrada con la celebración del Día del Bibliotecario, una magnífica iniciativa que, como dijo alguien, debe convertirse en una tradición cultural de Colombia.

  13. Don E. Detmer and the American Medical Informatics Association: An Appreciation

    Science.gov (United States)

    Shortliffe, Edward H.; Bates, David W.; Bloomrosen, Meryl; Greenwood, Karen; Safran, Charles; Steen, Elaine B.; Tang, Paul C.; Williamson, Jeffrey J.

    2009-01-01

    Don E. Detmer has served as President and Chief Executive Officer of the American Medical Informatics Association (AMIA) for the past five years, helping to set a course for the organization and demonstrating remarkable leadership as AMIA has evolved into a vibrant and influential professional association. On the occasion of Dr. Detmer's retirement, we fondly reflect on his professional life and his many contributions to biomedical informatics and, more generally, to health care in the U.S. and globally. PMID:19574463

  14. Application of gamma radiation to the nodes detection in Pinus Radiata (D.Don) wood pieces

    International Nuclear Information System (INIS)

    Morales, J.R.; Dinator, Maria I; Karsulovic C, Jose T.; Leon G, Adolfo

    1996-01-01

    Attenuation of 59.5 KeV photons provided by an Am-241 source, has been used to detect knots in lumber pieces from Pinus Radiata (D.Don). It is shown that the linear attenuation coefficient is a sensitive parameter to detect singularities in the structure of this material. The scanning of the piece provides profiles which define the position and extension of the singularity. (author)

  15. Inflatable Emergency Equipment I: Evaluation of Individual Inflatable Aviation Life Preserver Donning Tests

    Science.gov (United States)

    2014-12-01

    have to do so in the water. Shortly thereafter, the Survival Research Unit at CAMI devel- oped a prototype life preserver, with a primary goal of...calculate the various donning function times, as defined below. These were entered into IBM SPSS ® version 21 for statistical analysis. “TSO Test Time...inflation tubes, manual inflation triggering devices with pull tabs and CO2 cartridges, and designed to be reversible. The experimental life preserver

  16. Reproduction et Diversité Génétique chez Parkia biglobosa (Jacq.) G. Don

    NARCIS (Netherlands)

    Sina, S.

    2006-01-01

    Parkiabiglobosa(Jacq.)G.Don, African

  17. "Don't know" responses to risk perception measures: implications for underserved populations.

    Science.gov (United States)

    Waters, Erika A; Hay, Jennifer L; Orom, Heather; Kiviniemi, Marc T; Drake, Bettina F

    2013-02-01

    Risk perceptions are legitimate targets for behavioral interventions because they can motivate medical decisions and health behaviors. However, some survey respondents may not know (or may not indicate) their risk perceptions. The scope of "don't know" (DK) responding is unknown. Examine the prevalence and correlates of responding DK to items assessing perceived risk of colorectal cancer. Two nationally representative, population-based, cross-sectional surveys (2005 National Health Interview Survey [NHIS]; 2005 Health Information National Trends Survey [HINTS]), and one primary care clinic-based survey comprised of individuals from low-income communities. Analyses included 31,202 (NHIS), 1,937 (HINTS), and 769 (clinic) individuals. Five items assessed perceived risk of colorectal cancer. Four of the items differed in format and/or response scale: comparative risk (NHIS, HINTS); absolute risk (HINTS, clinic), and "likelihood" and "chance" response scales (clinic). Only the clinic-based survey included an explicit DK response option. "Don't know" responding was 6.9% (NHIS), 7.5% (HINTS-comparative), and 8.7% (HINTS-absolute). "Don't know" responding was 49.1% and 69.3% for the "chance" and "likely" response options (clinic). Correlates of DK responding were characteristics generally associated with disparities (e.g., low education), but the pattern of results varied among samples, question formats, and response scales. The surveys were developed independently and employed different methodologies and items. Consequently, the results were not directly comparable. There may be multiple explanations for differences in the magnitude and characteristics of DK responding. "Don't know" responding is more prevalent in populations affected by health disparities. Either not assessing or not analyzing DK responses could further disenfranchise these populations and negatively affect the validity of research and the efficacy of interventions seeking to eliminate health disparities.

  18. La parodia como marco estructural en Don Quijote y Los viajes de Gulliver

    Directory of Open Access Journals (Sweden)

    Alfonso Muñoz Corcuera

    2016-07-01

    Full Text Available Los viajes de Gulliver, de Jonathan Swift, es una de las obras más conocidas de la literatura universal. Sin embargo, su recepción actual, al menos en España, se produce sobre todo por medio de adaptaciones en las que no se puede apreciar el calado de la obra literaria original. En este estudio se pretende profundizar en el análisis de Los viajes de Gulliver a través de una comparación con Don Quijote, enfocándose en los recursos paródicos: mientras Don Quijote parodia los libros de caballerías, Los viajes de Gulliver parodia los libros de viajes. El principal objetivo de esta comparación no será tanto demostrar una influencia de la obra de Cervantes sobre la de Swift, sino, más bien, iluminar algunos aspectos de Los viajes de Gulliver. Gulliver´s Travels, of Jonathan Swift, is one of the most well-known works in world literature. However, its actual reception, at least in Spain, it´s produced mostly through adaptations in which it´s impossible to appreciate the profundity of the original literary work. In this article, I intend to dig deeply into the analysis of Gulliver´s Travels through a comparison with Don Quixote, focusing on the parodic resources: while Don Quixote parodies the books of chivalry, Gulliver´s Travels parodies travel books. The main goal of this comparison will not be to prove some influence of Cervantes´ work in Swift´s work, but to illuminate some aspects of Gulliver´s Travels.

  19. Reflections on Don Juan and on the utility of the unhappy love affair.

    Science.gov (United States)

    Bergel, Ernest

    2011-12-01

    Based on an unusual clinical experience of a teenage boy in child psychotherapy, two conclusions are proposed: (1) that the extremely unhappy, early love affairs that occur in most men's lives serve a valuable function in helping them separate from their mothers sufficiently to be able to realistically relate to appropriate marriage partners, and (2) that some Don Juans start new relationships in order to break them off, rather than the reverse.

  20. The voice of Cervantes «creator» in Don Quixote

    Directory of Open Access Journals (Sweden)

    Florencio Sevilla Arroyo

    2010-12-01

    Full Text Available The aim of this paper is identifying the genuine voice of the Cervantes creator in the multiple choir of fictitious intermediaries involved in the authorship and the story of Don Quijote (reporter, editor, translator, Cide Hamete, supernarrator, readers, etc. trying, at the same time, to gauging the sense and the scope of their interventions. It happens that Miguel de Cervantes keeps to himself a novelistic role radically different depending on whether it is about the «story of story» or the «story itself»: refering to the first one, the author is out of the cast, delegating the reconstruction of Don Quixote’s legend in multiple fictional masks always comically manipulated; on the other hand, when it is the turn to the novelistic design of the chivalrous adventures of Don Quixote and Sancho, the voice of Cervantes creator comes to the forefront in order to take on, —as the «final author»— all narrative responsibility with absolute omniscience and solemnity. The resulting Quijote can only be explained from the intersection of both attitudes: the risible story of the most solemn/serious and magnificent novelistic bet never tried out..

  1. The Rhetoric of Madness in Kathy Acker’s Don Quixote

    Directory of Open Access Journals (Sweden)

    Claudia Cao

    2017-07-01

    Full Text Available This essay examines the rhetorical experimentation of Don Quixote by Kathy Acker, starting from a theoretical concept central in the author’s thought: her search for a “language of the body”. A brief introduction to Kathy Acker’s plagiaristic poetics frames her narrative strategies between postmodern rewriting and pastiche. It shows the way in which her Don Quixote transposes the representative scheme of the chivalric quest into the contemporary value system with the aim of questioning Cervantes’ text as one of the canonical works of the Western literary tradition. The following section deepens three focal concepts of Acker’s theoretical works – body, madness, and norm – illuminating the connections between her rhetorical experimentation and the works by Luce Irigaray and Judith Butler. Finally, the paper will demonstrate how these concepts in Acker's rewriting of Don Quixote are strictly related to paradox, which she uses in order to actualize a “language of the body”: in the passage from the former novel to the postmodern work, madness has become the device which, from the semantic level to the rhetorical one, expresses Acker’s idea of language of the body, as an alternative and in contrast to the canonical language of the logos.

  2. A neural model for transient identification in dynamic processes with 'don't know' response

    International Nuclear Information System (INIS)

    Mol, Antonio C. de A.; Martinez, Aquilino S.; Schirru, Roberto

    2003-01-01

    This work presents an approach for neural network based transient identification which allows either dynamic identification or a 'don't know' response. The approach uses two 'jump' multilayer neural networks (NN) trained with the backpropagation algorithm. The 'jump' network is used because it is useful to dealing with very complex patterns, which is the case of the space of the state variables during some abnormal events. The first one is responsible for the dynamic identification. This NN uses, as input, a short set (in a moving time window) of recent measurements of each variable avoiding the necessity of using starting events. The other one is used to validate the instantaneous identification (from the first net) through the validation of each variable. This net is responsible for allowing the system to provide a 'don't know' response. In order to validate the method, a Nuclear Power Plant (NPP) transient identification problem comprising 15 postulated accidents, simulated for a pressurized water reactor (PWR), was proposed in the validation process it has been considered noisy data in order to evaluate the method robustness. Obtained results reveal the ability of the method in dealing with both dynamic identification of transients and correct 'don't know' response. Another important point studied in this work is that the system has shown to be independent of a trigger signal which indicates the beginning of the transient, thus making it robust in relation to this limitation

  3. Change and persistence in land surface phenologies of the Don and Dnieper river basins

    Energy Technology Data Exchange (ETDEWEB)

    Kovalskyy, V; Henebry, G M, E-mail: geoffrey.henebry@sdstate.ed [Geographic Information Science Center of Excellence (GIScCE), South Dakota State University, 1021 Medary Avenue, Wecota Hall 506B, Brookings, SD 57007-3510 (United States)

    2009-10-15

    The formal collapse of the Soviet Union at the end of 1991 produced major socio-economic and institutional dislocations across the agricultural sector. The picture of broad scale patterns produced by these transformations continues to be discovered. We examine here the patterns of land surface phenology (LSP) within two key river basins-Don and Dnieper-using AVHRR (Advanced Very High Resolution Radiometer) data from 1982 to 2000 and MODIS (Moderate Resolution Imaging Spectroradiometer) data from 2001 to 2007. We report on the temporal persistence and change of LSPs as summarized by seasonal integration of NDVI (normalized difference vegetation index) time series using accumulated growing degree-days (GDDI NDVI). Three land cover super-classes-forest lands, agricultural lands, and shrub lands-constitute 96% of the land area within the basins. All three in both basins exhibit unidirectional increases in AVHRR GDDI NDVI between the Soviet and post-Soviet epochs. During the MODIS era (2001-2007), different socio-economic trajectories in Ukraine and Russia appear to have led to divergences in the LSPs of the agricultural lands in the two basins. Interannual variation in the shrub lands of the Don river basin has increased since 2000. This is due in part to the better signal-to-noise ratio of the MODIS sensor, but may also be due to a regional drought affecting the Don basin more than the Dnieper basin.

  4. Effects of temperature and time on deoxynivalenol (DON and zearalenone (ZON content in corn

    Directory of Open Access Journals (Sweden)

    Jauković Marko

    2014-01-01

    Full Text Available Fumonisins are Fusarium mycotoxins that occur in corn and corn-based foods and they have been implicated in several animal and human diseases. Their effect on human health is unclear, however, fumonisins are considered to be risk factors for cancer. Baking, frying, and extrusion cooking of corn at high temperatures (190°C reduce fumonisin concentrations in foods, with the amount of reduction achieved depending on cooking time, temperature, recipe, and other factors. The aim of this work was to evaluate the effectiveness of temperature (200 and 220 °C and time (15 and 20 min on the detoxification of corn flour deliberately contaminated with DON and ZON. After processing at 200°C for 15 min, an average of 12% and after 20 min an average of 15% of DON was lost. At 200°C ZON content was reduced by 22% (after 15 min and by 27% (after 20 min. Higher temperature (220°C did not significantly affect further reduction of DON or ZON content. The process was only partially effective in both cases. [Projekat Ministarstva nauke Republike Srbije, br. TR-31023 i br. TR-31053

  5. El don: entre las prácticas intersticiales y el solidarismo

    Directory of Open Access Journals (Sweden)

    ADRIÁN SCRIBANO

    2014-08-01

    Full Text Available El presente trabajo busca hacer evidente al solidarismo como la "pérdida del don", conforme expuesto por Mauss, en el contexto de la situación colonial, de los procesos de expansión capitalista en la actualidad. Como objeto de análisis y mediación hermenéutica, hemos seleccionado a la Responsabilidad Social Empresarial (RSE como una forma del solidarismo cuyas prácticas llevan a un conjunto de situaciones que pueden describirse como pornográficas. Para lograr el objetivo explicitado, hemos seguido la siguiente estrategia argumentativa: a se sintetizan algunas pocas coordenadas de carácter teóricos que permitan entender la centralidad del don y se explicita nuestra idea de solidarismo, b se realiza un triple análisis: de la conceptualización de la RSE y de las experiencias de RSE de algunas corporaciones internacionales en Argentina; y c se exponen nuestras ideas sobre prácticas intersticiales en tanto hiatos que quiebran a la economía política de la moral como una totalidad que demanda la "pérdida" de todo tipo de don.

  6. Hubungan antara Aktivitas Fisik Terhadap Memori Kerja Murid SMA Don Bosco III Bekasi

    Directory of Open Access Journals (Sweden)

    Michelle Clarissa Junaidi

    2017-03-01

    Full Text Available Latar belakang. Memori kerja merupakan bagian dari memori jangka pendek yang berperan penting dalam membantu proses pembelajaran dan dipengaruhi oleh aktivitas fisik, memori kerja yang rendah akan menimbulkan kesulitan untuk menerima informasi baru serta penurunan prestasi belajar. Tujuan. Mengetahui pengaruh aktivitas fisik terhadap kapasitas memori kerja murid SMA Don Bosco III. Metode. Penelitian metode analitik dengan pendekatan potong lintang pada 113 murid SMA Don Bosco III, Bekasi, pada 18 – 20 Juli 2016. Penelitian dilakukan dengan menggunakan kuesioner demografi, kuesioner skrining gangguan mental dan penyakit kronis, Physical Acitivity Questionnaire of Adolescent (PAQ-A dan Operation Span (O-SPAN. Analisis data dengan univariat dan bivariat menggunakan uji korelasi Spearman. Hasil. Terdapat 113 murid SMA Don Bosco III dengan kisaran usia 14 – 17 tahun, usia terbanyak 15 tahun (47.8%, laki-laki 61,1%, murid kelas X 44.2%. Mayoritas responden memiliki aktivitas fisik “kurang baik” dan rerata memori kerja 6,16. Analisis Spearman menunjukkan terdapat hubungan bermakna (p<0,05 antara aktivitas fisik terhadap memori kerja dengan korelasi positif lemah (r=0,384. Kesimpulan. Terdapat korelasi positif antara aktivitas fisik dan memori kerja, aktivitas fisik yang semakin tinggi cenderung akan meningkatkan memori kerja.

  7. Change and persistence in land surface phenologies of the Don and Dnieper river basins

    International Nuclear Information System (INIS)

    Kovalskyy, V; Henebry, G M

    2009-01-01

    The formal collapse of the Soviet Union at the end of 1991 produced major socio-economic and institutional dislocations across the agricultural sector. The picture of broad scale patterns produced by these transformations continues to be discovered. We examine here the patterns of land surface phenology (LSP) within two key river basins-Don and Dnieper-using AVHRR (Advanced Very High Resolution Radiometer) data from 1982 to 2000 and MODIS (Moderate Resolution Imaging Spectroradiometer) data from 2001 to 2007. We report on the temporal persistence and change of LSPs as summarized by seasonal integration of NDVI (normalized difference vegetation index) time series using accumulated growing degree-days (GDDI NDVI). Three land cover super-classes-forest lands, agricultural lands, and shrub lands-constitute 96% of the land area within the basins. All three in both basins exhibit unidirectional increases in AVHRR GDDI NDVI between the Soviet and post-Soviet epochs. During the MODIS era (2001-2007), different socio-economic trajectories in Ukraine and Russia appear to have led to divergences in the LSPs of the agricultural lands in the two basins. Interannual variation in the shrub lands of the Don river basin has increased since 2000. This is due in part to the better signal-to-noise ratio of the MODIS sensor, but may also be due to a regional drought affecting the Don basin more than the Dnieper basin.

  8. The silent Don Juan. The concepts of love and art in the works of Max Frisch

    Directory of Open Access Journals (Sweden)

    Špela Virant

    2012-07-01

    Full Text Available In the novel Stiller and in the play Don Juan, both published in the early 1950s, Frisch already focuses on the problem of identity as one of his major themes, but it is not yet situated in a political context as, for example, in the play Andorra. In these works, the identity-problem is situated in the domain of intimate relationships and artistic creativity, offering the possibility to discuss Frisch’s concepts of art and love, which unfold through Frisch’s treatment of the traditional literary figure of Don Juan and his hubris. Frisch’s Stiller and Don Juan do not believe in God; but their frame of mind stays the same, while the position of God and his attributes are assigned to love, art and geometry. Although both literary figures in the course of events realize that this substitution is a mistake, they are unable to alter their concepts of love and art. Instead of altering the concepts, they rather resign in silence, while Max Frisch continues to search for alternatives in reflecting on the process of fictionalization and in developing innovative narrative and dramatic structures.

  9. de "subirnos al tiempo". La economía del "don"

    Directory of Open Access Journals (Sweden)

    Raúl García Durán

    2007-01-01

    Full Text Available Este trabajo resume las ideas contenidas en el libro -aún inédito- De la miseria de la economía a la plenitud de la fraternidad; o la economía del "don" como alternativa al capitalismo y la economía de mercado. En él se plantean alternativas radicales al capitalismo; particularmente, se ubica al "don" como camino de pensamiento y acción. Se documentan las proposiciones teóricas y aportes de la economía política, la antropología, la historia, para construir la manera en que el don podría contribuir a una reorganización social basada en nuevos-viejos principios. Se interrogan diversas experiencias histórico-antropológicas y su prefiguración actual en un nuevo modelo ético-político-ecológico que abarca las dimensiones local y global.

  10. Investigation of the fluid-structure interaction of a high head Francis turbine using OpenFOAM and Code_Aster

    Science.gov (United States)

    Eichhorn, M.; Doujak, E.; Waldner, L.

    2016-11-01

    The increasing energy consumption and highly stressed power grids influence the operating conditions of turbines and pump turbines in the present situation. To provide or use energy as quick as possible, hydraulic turbines are operated more frequent and over longer periods of time in lower part load at off-design conditions. This leads to a more turbulent behavior and to higher requirements of the strength of stressed components (e.g. runner, guide or stay vanes). The modern advantages of computational capabilities regarding numerical investigations allow a precise prediction of appearing flow conditions and thereby induced strains in hydraulic machines. This paper focuses on the calculation of the unsteady pressure field of a high head Francis turbine with a specific speed of nq ≈ 24 min-1 and its impact on the structure at different operating conditions. In the first step, unsteady numerical flow simulations are performed with the open-source CFD software OpenFOAM. To obtain the appearing dynamic flow phenomena, the entire machine, consisting of the spiral casing, the stay vanes, the wicket gate, the runner and the draft tube, is taken into account. Additionally, a reduced model without the spiral casing and with a simplified inlet boundary is used. To evaluate the accuracy of the CFD simulations, operating parameters such as head and torque are compared with the results of site measurements carried out on the corresponding prototype machine. In the second part, the obtained pressure fields are used for a fluid-structure analysis with the open-source Finite Element software Code_Aster, to predict the static loads on the runner.

  11. The Battle Between the Biometricians and the Mendelians: How Sir Francis Galton's Work Caused his Disciples to Reach Conflicting Conclusions About the Hereditary Mechanism

    Science.gov (United States)

    Gillham, Nicholas W.

    2015-01-01

    Francis Galton, Charles Darwin's cousin, had wide and varied interests. They ranged from exploration and travel writing to fingerprinting and the weather. After reading Darwin's On the Origin of Species, Galton reached the conclusion that it should be possible to improve the human stock through selective breeding, as was the case for domestic animals and cultivated plants. Much of the latter half of Galton's career was devoted to trying to devise methods to distinguish men of good stock and then to show that these qualities were inherited. But along the way he invented two important statistical methods: regression and correlation. He also discovered regression to the mean. This led Galton to believe that evolution could not proceed by the small steps envisioned by Darwin, but must proceed by discontinuous changes. Galton's book Natural Inheritance (1889) served as the inspiration for Karl Pearson, W.F.R. Weldon and William Bateson. Pearson and Weldon were interested in continuously varying characters and the application of statistical techniques to their study. Bateson was fascinated by discontinuities and the role they might play in evolution. Galton proposed his Law of Ancestral Heredity in the last decade of the nineteenth century. At first this seemed to work well as an explanation for continuously varying traits of the type that interested Pearson and Weldon. In contrast, Bateson had published a book on discontinuously varying traits so he was in a position to understand and embrace Mendel's principles of inheritance when they were rediscovered in 1900. The subsequent battle between Weldon and Pearson, the biometricians, and Bateson, the Mendelian, went on acrimoniously for several years at the beginning of the twentieth century before Mendelian theory finally won out.

  12. Vortical structures and pressure pulsations in draft tube of a Francis-99 turbine at part load: RANS and hybrid RANS/LES analysis

    International Nuclear Information System (INIS)

    Gavrilov, A.A.; Sentyabov, A.V.; Dekterev, A.A.; Hanjalić, K.

    2017-01-01

    Highlights: • Simulations showed the formation of spiralling coherent vortices in the draft tube. • Both hybrid RANS-LES and Re-stress models reproduced well the measured fluctuations. • Re-stress model resolved the precessing vortex core and coherent spiralling vortices. - Abstract: Recognizing the limitations of the conventional linear-eddy-viscosity (LEVM) Reynolds-averaged Navier–Stokes (RANS) models to reproduce complex three-dimensional unsteady flows in hydraulic machinery, we performed a comparative assessment of a second-moment (Re-stress model, RSM) RANS closure and a hybrid RANS/LES method in capturing the flow and vortical structures in the draft tube of a Francis hydroturbine at off-design conditions. Considered is a case of part load (PL) at a flow rate of only 35% of the best efficiency point (BEP) characterised by multiple unsteady vortex systems. Despite some remaining uncertainties in generating the inflow conditions, both approaches reproduced reasonably well the measured mean velocity and the rms of its fluctuations, as well as the pressure spectrum with peaks detecting the precessing vortex core. In contrast to the common LEVMs, the Re-stress closure showed sufficient receptivity to intrinsic unsteadiness and reproduced well the overall flow and vortical patterns as well as the associated pressure pulsations in accord with the experiments. The hybrid RANS/LES method gave similar predictions as the RSM, but resolving a wider range of scales, which however, showed no significant effect on the dynamics of the dominant processing vortex core and the pressure pulsations.

  13. Information Technology Portfolio Management and the Real Options Method (ROM): Managing the Risks of IT Investments in the Department of the Navy (DON)

    National Research Council Canada - National Science Library

    Davis, Jeffery

    2003-01-01

    .... This research draws upon ITPM implementation strategies currently employed by the DON and provides recommendations for managing the inherent risk in IT investments, specifically the application...

  14. Preliminary study for the revitalisation of the 'Duersteller' small hydropower installation in Wetzikon, Switzerland; Vorstudie Kleinwasserkraftwerk J. Duersteler and Co AG Wetzikon ZH. Revitalisierungsvorhaben des Kraftwerkes mit seinen 80-jaehrigen Francis-Doppelturbinen

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    This report for the Swiss Federal Office of Energy (SFOE) discusses the possibility of revitalising an 80-year-old, small industrial hydropower plant fitted with twin Francis turbines. The present situation and the condition of the turbines and their associated water channels are described and the hydrological data of the Aabach stream is presented. Details are given on the presently installed technical apparatus and the legal and ownership situation. Environmental and historical aspects are discussed. The economics of the proposed revitalisation project are discussed and possible restrictions that could be enforced by the authorities are looked at. The report is concluded with recommendations for further action.

  15. Influence of Hydraulic Design on Stability and on Pressure Pulsations in Francis Turbines at Overload, Part Load and Deep Part Load based on Numerical Simulations and Experimental Model Test Results

    International Nuclear Information System (INIS)

    Magnoli, M V; Maiwald, M

    2014-01-01

    Francis turbines have been running more and more frequently in part load conditions, in order to satisfy the new market requirements for more dynamic and flexible energy generation, ancillary services and grid regulation. The turbines should be able to be operated for longer durations with flows below the optimum point, going from part load to deep part load and even speed-no-load. These operating conditions are characterised by important unsteady flow phenomena taking place at the draft tube cone and in the runner channels, in the respective cases of part load and deep part load. The current expectations are that new Francis turbines present appropriate hydraulic stability and moderate pressure pulsations at overload, part load, deep part load and speed-no-load with high efficiency levels at normal operating range. This study presents series of investigations performed by Voith Hydro with the objective to improve the hydraulic stability of Francis turbines at overload, part load and deep part load, reduce pressure pulsations and enlarge the know-how about the transient fluid flow through the turbine at these challenging conditions. Model test measurements showed that distinct runner designs were able to influence the pressure pulsation level in the machine. Extensive experimental investigations focused on the runner deflector geometry, on runner features and how they could reduce the pressure oscillation level. The impact of design variants and machine configurations on the vortex rope at the draft tube cone at overload and part load and on the runner channel vortex at deep part load were experimentally observed and evaluated based on the measured pressure pulsation amplitudes. Numerical investigations were employed for improving the understanding of such dynamic fluid flow effects. As example for the design and experimental investigations, model test observations and pressure pulsation curves for Francis machines in mid specific speed range, around n qopt = 50

  16. Cervantes, Lizardi, and the Literary Construction of The Mexican Rogue in Don Catrín de la fachenda

    Directory of Open Access Journals (Sweden)

    Vilches Patricia

    2017-12-01

    Full Text Available This study explores the socio-economic legacies and critique of nation-building found in the work of Jose Joaquin Fernandez de Lizardi (1776-1827. In the nineteenth century, the Latin American elite struggled to disassociate itself from a suffocating colonial machine; they sought their own identity, and writing became a way to express their frustration. As in other parts of Latin America, Mexican intellectuals protested fossilisation via Cervantes’s Don Quijote. Using the Spanish author’s text as a blueprint, Lizardi’s Don Catrín de la fachenda depicted a turbulent society that was in the process of abandoning a decaying colonial order. Don Quijote’s characters engaged in power struggles and were involved in a variety of forms of social antagonism. Lizardi juxtaposed and superimposed these on an American geographical and socio-economic space where there was much dissension around the nation’s direction. The social and economic rules of Mexico (and Latin America today can be said to be already present in the social exchanges in Don Catrín. It was in this context that Don Quijote was “Mexicanised” by Lizardi and thereby made to participate in local reflections on liberty, patriotism, capitalism, and citizenship. Cervantes’s text thus took on a socio-political meaning in the narrative of Latin America’s past and present.

  17. De la risa a carcajadas al mal ejemplo quijotesco en la novela del XVIII. Don Quijote de la Manchuela

    Directory of Open Access Journals (Sweden)

    Agapita Jurado Santos

    2013-03-01

    Full Text Available Don Quixote rapidly became a huge success. It was translated into several languages and reworked into genres with a festive and theatrical nature. In Spain, during the seventeenth century, its comic side was exploited, which provoked liberating laughter that, in France, led to its association with the satire genre. In the eighteenth century, the novel was considered a minor genre, of no educational value. The century began with a fierce controversy over the meaning of Cervantes’ work, since according to Rapin, some readers would have seen a mockery of the Spanish nobility in the insane gentleman. However, during the eighteenth century the first steps were taken to reappraise Don Quixote due to its acceptance as a classic by the Spanish Royal Academy in 1780. The Academy considered Don Quixote a mocking and didactic hero, a bad example to be avoided. Yet, the work was an important step in the construction of a new genre, the novel. Don Quijote de la Manchuela, by Donato de Arenzana (1767, reflects an attentive reading of Cervantes’ Don Quixote, and special attention to the neoclassical cannon. Therefore it can provide useful information about writers’ interests, in the preromantic eighteenth century.

  18. Transcriptome analysis of the human T lymphocyte cell line Jurkat and human peripheral blood mononuclear cells exposed to deoxynivalenol (DON): New mechanistic insights

    Energy Technology Data Exchange (ETDEWEB)

    Katika, Madhumohan R. [RIKILT-Institute of Food Safety, Wageningen University and Research Centre, Wageningen (Netherlands); Department of Health Risk Analysis and Toxicology, Maastricht University (Netherlands); Netherlands Toxicogenomics Centre (Netherlands); Hendriksen, Peter J.M. [RIKILT-Institute of Food Safety, Wageningen University and Research Centre, Wageningen (Netherlands); Netherlands Toxicogenomics Centre (Netherlands); Shao, Jia [RIKILT-Institute of Food Safety, Wageningen University and Research Centre, Wageningen (Netherlands); Department of Health Risk Analysis and Toxicology, Maastricht University (Netherlands); Netherlands Toxicogenomics Centre (Netherlands); Loveren, Henk van [Department of Health Risk Analysis and Toxicology, Maastricht University (Netherlands); National Institute for Public Health and the Environment (RIVM), Bilthoven (Netherlands); Netherlands Toxicogenomics Centre (Netherlands); Peijnenburg, Ad, E-mail: ad.peijnenburg@wur.nl [RIKILT-Institute of Food Safety, Wageningen University and Research Centre, Wageningen (Netherlands); Netherlands Toxicogenomics Centre (Netherlands)

    2012-10-01

    Deoxynivalenol (DON) or vomitoxin is a commonly encountered type-B trichothecene mycotoxin, produced by Fusarium species predominantly found in cereals and grains. DON is known to exert toxic effects on the gastrointestinal, reproductive and neuroendocrine systems, and particularly on the immune system. Depending on dose and exposure time, it can either stimulate or suppress immune function. The main objective of this study was to obtain a deeper insight into DON-induced effects on lymphoid cells. For this, we exposed the human T-lymphocyte cell line Jurkat and human peripheral blood mononuclear cells (PBMCs) to various concentrations of DON for various times and examined gene expression changes by DNA microarray analysis. Jurkat cells were exposed to 0.25 and 0.5 μM DON for 3, 6 and 24 h. Biological interpretation of the microarray data indicated that DON affects various processes in these cells: It upregulates genes involved in ribosome structure and function, RNA/protein synthesis and processing, endoplasmic reticulum (ER) stress, calcium-mediated signaling, mitochondrial function, oxidative stress, the NFAT and NF-κB/TNF-α pathways, T cell activation and apoptosis. The effects of DON on the expression of genes involved in ER stress, NFAT activation and apoptosis were confirmed by qRT-PCR. Other biochemical experiments confirmed that DON activates calcium-dependent proteins such as calcineurin and M-calpain that are known to be involved in T cell activation and apoptosis. Induction of T cell activation was also confirmed by demonstrating that DON activates NFATC1 and induces its translocation from the cytoplasm to the nucleus. For the gene expression profiling of PBMCs, cells were exposed to 2 and 4 μM DON for 6 and 24 h. Comparison of the Jurkat microarray data with those obtained with PBMCs showed that most of the processes affected by DON in the Jurkat cell line were also affected in the PBMCs. -- Highlights: ► The human T cell line Jurkat and human

  19. Don Quijote de la Mancha: Reflexiones en torno a las relaciones cine-literatura Don Quijote de la Mancha: Reflections about the relationships between cinematography-literature

    Directory of Open Access Journals (Sweden)

    Felipe Ardila Rojas

    2008-06-01

    Full Text Available Este artículo presenta un análisis de algunos aspectos de la relación cine-literatura, a partir del Don Quijote de La Mancha literario y de algunas versiones cinematográficas y televisivas realizadas en español y en inglés. Inicialmente se presentan problemas teóricos en torno a categorías que suelen serles afines: relato, autor, narración, historia, etc., para involucrar alternativamente fenómenos que, desde el punto de vista de los autores, generan ambigüedades textuales o múltiples interpretaciones en las versiones que se analizan. De este análisis comparativo que parte de los relatos en cuestión se llega finalmente a conclusiones de carácter estético e ideológico sobre los mismos.This article presents an analysis of some aspects of the relationship between cinematography and literature. Starting from the Don Quijote de La Mancha and taking into account some film and television versions developed in Spanish and English. At the beginning, a theoretical problem based on similar types for concepts categorization: author, narration, story, relat, among others will be analyzed. In addition, a connection is made with some authors' concepts in order to avoid textual ambiguity or multiple interpretations in the versions that are analyzed. Through a comparative analysis supported in these stories, it is possible to reach some aesthetic and ideological conclusions about them.

  20. Review of Ordering Don't Resuscitate in Iranian Dying Patients.

    Science.gov (United States)

    Cheraghi, Mohammad Ali; Bahramnezhad, Fatemeh; Mehrdad, Neda

    2018-06-01

    Making decision on not to resuscitate is a confusing, conflicting and complex issue and depends on each country's culture and customs. Therefore, each country needs to take action in accordance with its cultural, ethical, religious and legal contexts to develop guidelines in this regard. Since the majority of Iran's people are Muslims, and in Islam, the human life is considered sacred, based on the values of the community, an Iranian Islamic agenda needs to be developed not taking measures about resuscitation of dying patients. It is necessary to develop an Iranian Islamic guidelines package in order to don't resuscitate in dying patients.

  1. An Analysis of Insults in Don Quixote from the Perspective of Social History of Language

    Directory of Open Access Journals (Sweden)

    Jesús M. Usunáriz

    2017-11-01

    Full Text Available Daily use of insult, slander, in the societies of the Early Modern Age, is also present in the voices of the protagonists of Don Quixote. However, the Ingenious Gentleman and his squire, do not use the insult in the same way. This will depend on the social position of insulted and offender (noble or villain, and the circumstances surrounding it. However, social reality, collected in different court cases, shows that the insult did not respect, in the same way as in the novel, the stratified social structure.

  2. The Knight-errant and their Itinerary. Journey and />Death of Don Quixote

    Directory of Open Access Journals (Sweden)

    Nieves Rodríguez Valle

    2016-01-01

    Full Text Available This article analyzes, from the perspective of the hero’s journey topic in the narrative, the wanderings of Don Quixote on the Spanish roads and in the spaces of the chivalric literature. Based on the four narrative sequences that stake out the itinerary in the journey narrative: departure, cruise, meeting, and return, the three departures and the three returns of the knight in the work are reviewed, specially the last return and the relationship that it keeps with his death.

  3. Juan Bautista Avalle Arce y el escrutinio de la librería de Don Quijote

    OpenAIRE

    Nállim, Carlos Orlando

    2000-01-01

    En este trabajo se destacan los aportes de Avalle Arce a la crítica del Quijote que lo convierten en el "cervantista actual por antonomasia". Se señalan sus grandes aciertos: la peculiar tesis del crítico acerca de la relación que se establece entre vida y literatura; la influencia en la vida de Don Quijote no sólo de los libros de caballería sino también de muchos otros que conformaban su abundante biblioteca; la solución que aporta al trillado tema cordura/locura del personaje...

  4. Jasminum extensum Wall. ex G. Don (Oleaceace, a New Record to the Flora of Vietnam

    Directory of Open Access Journals (Sweden)

    Bui Hong Quang

    2013-06-01

    Full Text Available One rare, poorly known species from India, South China and Thailand - Jasminum extensum Wall. ex G. Don is recently discovered in Vietnam representing a new record to the flora of the country. The plant differs from its closely related species viz. Jasminum pierreanum in having coriaceous leaves and 5–6 primary veins in each side of the mid-rib. Detailed information on taxonomy, types, morphology, habitat, ecology, distribution and studied voucher specimens, as well as illustrations are provided here for species identification.

  5. Don José Joquín Casas : un hombre una época

    Directory of Open Access Journals (Sweden)

    Rafael Azula Barrera

    1966-03-01

    Full Text Available Debo a las generosas instancias del reverendo padre Félix Restrepo -cuyo tránsito terrenal, concluído al finalizar el año último, se halla constelado de hazañas que reclaman ser esculpidas, como alto relieves, en el propio pedestal de la estatua que la gratitud nacional habrá de levantar a su nombre el honor inmerecido de pronunciar las palabras de rigor, al conmemorar nuestro instituto, en este día del idioma, el primer centenario del nacimiento de don José Joaquín Casas.

  6. Chemical Composition and Possible in Vitro Phytotoxic Activity of Helichrsyum italicum (Roth Don ssp. italicum

    Directory of Open Access Journals (Sweden)

    Vincenzo De Feo

    2011-09-01

    Full Text Available The chemical composition of the essential oil of Helichrysum italicum (Roth Don ssp. italicum, collected in the National Park of Cilento and Diano Valley, Southern Italy, was studied by means of GC and GC/MS. Forty four compounds of 45 constituents were identified in the oil, mainly oxygenated sesquiterpenes. The essential oil was evaluated for its potential in vitro phytotoxic activity against germination and early radicle elongation of radish and garden cress. The radicle elongation of radish was significantly inhibited at the highest doses tested, while germination of both seeds was not affected.

  7. The invisible teenager: Comic book materiality and the amateur films of Don Glut

    Directory of Open Access Journals (Sweden)

    Matt Yockey

    2014-06-01

    Full Text Available Don Glut, between the ages of 9 and 25, made 41 short amateur films inspired by horror, science fiction, and superhero movies, serials, and comic books. The tactile qualities of comic books as affect-generating objects are instrumental to how Glut confirmed his identity during a time (adolescence in which that identity is particularly unstable. Glut used the popular figure of the teen rebel and his role as a filmmaker in order to negotiate with hegemonic restrictions on his objects of affection, especially comic books.

  8. The Landscape of Cervante´s Don Quixote: Orteguians Perspectives

    Directory of Open Access Journals (Sweden)

    Ángel Pérez Martínez

    2013-12-01

    Full Text Available Perspectival theory, related to Don Quixote by the many references in the corpus of Ortega, enables further research about the importance of the landscape and the physical description in order to understand the work of Cervantes. Similarly, it should be mentioned its relation with the development of literary theory. Such investigations give an interesting point of view under the framework called travel genre and its tangential contact with Quijote. On the other hand, and because of the publication of Obras Completas by Ortega, we find ourselves with a new order of the writings from the philosopher and an appropriate index for research.

  9. For the Amusement of the Merry Little Subjects: How British Children Met Don Quixote in the Long Eighteenth Century

    Directory of Open Access Journals (Sweden)

    Miriam Borham Puyal

    2015-12-01

    Full Text Available As a masterpiece, Don Quixote has become an easily recognizable myth, sometimes reduced to well-known episodes such as the tilting at windmills or the blanket-tossing of Sancho. These elements are emphasised in editions of this classic for children, highlighting the importance these versions have for the understanding of the widespread popularity of Cervantes’ novel, in general, and of certain scenes, in particular. The present article explores the relationship of the child reader to Don Quixote and provides an overview of how English children might have encountered it in the long eighteenth century (1660-1832. It connects chapbooks, abridgments and children’s books to suggest that children might have been among its earliest readers and to emphasise the intertextual continuum and the richness in the reception of Don Quixote in England, from the seventeenth to the nineteenth century.

  10. Gender differences in national assessment of educational progress science items: What does i don't know really mean?

    Science.gov (United States)

    Linn, Marcia C.; de Benedictis, Tina; Delucchi, Kevin; Harris, Abigail; Stage, Elizabeth

    The National Assessment of Educational Progress Science Assessment has consistently revealed small gender differences on science content items but not on science inquiry items. This assessment differs from others in that respondents can choose I don't know rather than guessing. This paper examines explanations for the gender differences including (a) differential prior instruction, (b) differential response to uncertainty and use of the I don't know response, (c) differential response to figurally presented items, and (d) different attitudes towards science. Of these possible explanations, the first two received support. Females are more likely to use the I don't know response, especially for items with physical science content or masculine themes such as football. To ameliorate this situation we need more effective science instruction and more gender-neutral assessment items.

  11. Bioanalysis of 6-Diazo-5-oxo-L-norleucine (DON) in plasma and brain by ultra-performance liquid chromatography mass spectrometry

    Science.gov (United States)

    Alt, Jesse; Potter, Michelle C.; Rojas, Camilo; Slusher, Barbara S.

    2015-01-01

    Glutamine is an abundant amino acid that plays pivotal roles in cell growth, cell metabolism and neurotransmission. Dysregulation of glutamine-utilizing pathways has been associated with pathological conditions such as cancer and neurodegenerative diseases. 6-Diazo-5-Oxo-L-Norleucine (DON) is a reactive glutamine analog that inhibits enzymes affecting glutamine metabolism such as glutaminase, 2-N-amidotransferase, L-asparaginase and several enzymes involved in pyrimidine and purine de novo synthesis. As a result, DON is actively used in preclinical models of cancer and neurodegenerative disease. Moreover, there have been several clinical trials using DON to treat a variety of cancers. Considerations of dose and exposure are especially important with DON treatment due to its narrow therapeutic window and significant side effects. Consequently, a robust quantification bioassay is of interest. DON is a polar unstable molecule which has made quantification challenging. Here we report on the characterization of a bioanalytical method to quantify DON in tissue samples involving DON derivatization with 3N HCl in butanol. The derivatized product is lipophilic and stable. Detection of this analyte by mass spectrometry is fast, specific and can be used to quantify DON in plasma and brain tissue with a limit of detection in the low nanomolar level. PMID:25584882

  12. Don Quijote y los eruditos: Sobre una polémica crítica y sus implicaciones metacríticas

    OpenAIRE

    Pardo García, Pedro Javier

    2000-01-01

    [ES]Este trabajo trata sobre Don Quijote y los eruditos: una polémica crítica y sus implicaciones metacríticas. [EN]This paper deals with Don Quixote and scholars: a critical controversy and its implications metacritica.

  13. Don Quijote y los eruditos: Sobre la sátira quijotesca de la pedantería en la literatura francesa del siglo XVIII

    OpenAIRE

    Pardo García, Pedro Javier

    1998-01-01

    [ES]Este texto trata Don Quijote y los eruditos, una polémica crítica y sus implicaciones metacríticas. [EN]This text is Don Quixote and scholars, a critical controversy and its implications metacritical.

  14. Don Yllán and the Egyptian Sorcerer: Vernacular commonality and literary diversity in medieval Castile

    Directory of Open Access Journals (Sweden)

    Wacks, David A.

    2005-12-01

    Full Text Available In this article the author compares the exemplo of Don Yllán and the Deán de Santiago -no. 11 in Don Juan Manuel's Conde Lucanor (ca. 1335- with an earlier Hebrew analogue found in the Hebrew Mešal Haqadmonī (ca. 1285 of fellow Castilian author Isaac ibn Sahula. A thorough analysis of the rhetorical and narrative style of both versions reveals that the two tales shared a common source in Castilian oral tradition. The appearance of the tale in an earlier Hebrew text from Castile (the only other known version in any language calls into question the originality of Don Juan Manuel's most famous exemplo, suggesting a productive interplay between a common oral tradition in Castilian and coexisting literary traditions in Hebrew and Castilian.

    En este artículo, el autor compara el exemplo de Don Yllán y el Deán de Santiago -n.° 11 en el Conde Lucanor (ca. 1335 de Don Juan Manuel- con una versión anterior en la obra hebrea, Mešal Haqadmonī (ca. 1285 de otro autor castellano, Isaac ibn Sahula. Un análisis cuidadoso del estilo narrativo y retórico de ambas versiones revela que las dos comparten una fuente común en la tradición oral castellana. La aparición del cuento en un texto hebreo anterior de Castilla (la única versión conocida en cualquier otra lengua cuestiona la originalidad literaria del más famoso exemplo de Don Juan Manuel, y sugiere un intercambio productivo entre una tradición oral común castellana y tradiciones literarias hebreas y castellanas coexistentes.

  15. Postmodernism, phenomenology and afriphenomenology | Francis ...

    African Journals Online (AJOL)

    In this paper, I aimed to study the relationship between postmodernism and phenomenology. In the study, I established that postmodernism and phenomenology bear similar ontological marking, which base their concepts and methodologies on an individualistic framework. On the basis of such ontological framework, ...

  16. St Francis Hydro, Soils data

    Data.gov (United States)

    U.S. Environmental Protection Agency — We collected data 2012-2016 covering spatially-explicit, soil layering, bulk density, drainage rate (2012, 2015) infiltration into rain garden mulch and mineral soil...

  17. Identiteet ja migratsioon / Francis Fukuyama

    Index Scriptorium Estoniae

    Fukuyama, Francis

    2007-01-01

    Autor peab islamiäärmuslust immigrantide identiteedikriisi ilminguks ning arutleb identiteedipoliitika olemuse ja tuleviku üle Euroopa ja Ameerika postmodernses multikultuurilises ühiskonnas. Vt. samas: Jeffrey Goldstein: Euroopa ja USA - konkurendid või partnerid

  18. DON shares a similar mode of action as the ribotoxic stress inducer anisomycin while TBTO shares ER stress patterns with the ER stress inducer Thapsigargin based on comparative gene expression profiling in Jurkat T cells

    NARCIS (Netherlands)

    Schmeits, P.C.J.; Katika, M.R.; Peijnenburg, A.A.C.M.; Loveren, van H.; Hendriksen, P.J.M.

    2014-01-01

    Previously, we studied the effects of deoxynivalenol (DON) and tributyltin oxide (TBTO) on whole genome mRNA expression profiles of human T lymphocyte Jurkat cells. These studies indicated that DON induces ribotoxic stress and both DON and TBTO induced ER stress which resulted into T-cell activation

  19. On the effects of the Fusarium toxin deoxynivalenol (DON) administered per os or intraperitoneal infusion to sows during days 63 to 70 of gestation.

    Science.gov (United States)

    Goyarts, Tanja; Brüssow, Klaus-Peter; Valenta, Hana; Tiemann, Ute; Jäger, Kathrin; Dänicke, Sven

    2010-05-01

    Six pregnant sows of 180.6 ± 5.6 kg were fed either a Fusarium-contaminated (4.42 mg DON and 48.3 µg ZON per kg, DON per os, n = 3) or a control diet (0.15 mg DON and 5 µg ZON/kg) in the period of days 63 and 70 of gestation. On day 63 of gestation, sows fed the control diet were implanted with an intraperitoneal osmotic minipump (delivery rate of 10 µL/h, for 7 days) containing 50 mg pure (98%) DON in 2 ml 50% DMSO (DON ip, n = 3). Frequent plasma samples were taken to estimate the kinetics after oral and ip DON exposure. The intended continuous delivery of DON by the intraperitoneal minipump could not be shown, as there was a plasma peak (Cmax) of 4.2-6.4 ng DON/mL either immediately (sow IP-2+3) or 2.5 h (sow IP-1) after implantation of the pump followed by a one-exponential decline with a mean half-time (t1/2) of 1.75-4.0 h and only negligible DON plasma concentrations after 12 h. Therefore, the DON ip exposure has to be regarded as one single dose 1 week before termination of experiment. The DON per os sows showed a mean basis level (after achieving a steady state) of DON plasma concentration of about 6-8 ng/mL, as also indicated by the plasma DON concentration at the termination of the experiment. On day 70, caesarean section was carried out, the fetuses were killed immediately after birth, and samples of plasma, urine, and bile were taken to analyze the concentration of DON and its metabolite de-epoxy-DON. At necropsy there were no macroscopic lesions observed in any organ of either sows or piglets. Histopathological evaluation of sows liver and spleen revealed no alterations. The proliferation rate of peripheral blood mononuclear cells (PBMC) with or without stimulation was not affected by the kind of DON treatment. The exposure of pregnant sows at mid-gestation (days 63-70, period of organogenesis) to a Fusarium toxin-contaminated diet (4.42 mg DON and 0.048 mg ZON per kg) or pure DON via intraperitoneal osmotic minipump

  20. The occurrence of Fusarium toxins (zearalenone, DON, fumonisin, and T2) in some food commodities and feedstuffs in Syria

    Energy Technology Data Exchange (ETDEWEB)

    Ghanem, I; Al-Arfe, M [Atomic Energy Commission, Damascus (Syrian Arab Republic). Dept. of Molecular Biology and Biotechnology

    2010-01-15

    The presence of four Fusarium toxins (namely, zearalenone, Don, fuminosin, and T2) was studied in 129 food commodities and feedstuff samples using an enzyme-linked immunosorbent assay (ELISA). Results showed that the percentages of wheat samples contaminated with T2, fuminosin, Don and Zearalenone were : 33%, 31%, 11.6% and 12.5% for each toxin, respectively. Concentrations of these toxins in the contaminated samples fell in the range of 81 - 350, 330 - 1330, 270 - 420 and 42-67 {mu}g kg-1 for each toxin respectively. Barely samples showed higher percentages of contamination with those toxins amounting to 75.9%, 83.3%, 75% and 83.3% with concentrations ranging between 89-145, 270 - 1230, 650 - 3450 and 42-102 {mu}g kg-1 for T2, , fuminosin, Don and Zearalenone, respectively. Percentages of contaminated bran samples were 80% for T2 and 100% for each of fumonisin, Don and zearalenone. Concentrations of T2, fuminosin, Don and Zearalenone in bran samples ranged between 81-322 , 510 - 1670 , 280 - 750 and 42-81 {mu}g kg-1, respectively. All four tested toxins were present in corn samples. Levels of T2, , fuminosin, Don and Zearalenone in corn samples were in the range of 112-426 , 730 - 1820, 590 - 1080 and 63-112 {mu}g kg-1, respectively. Similarly, 100% of examined soya seed cake samples were found contaminated with various levels of the four assayed toxins, with levels of contamination ranging between 98-142 , 1340 - 2220 , 330 - 800 and 93-114 {mu}g kg-1, for T2, , fuminosin, Don and Zearalenone, respectively. All cotton seed cake samples were contaminated with the four tested toxins with contamination levels ranging between 94 - 142, 1120 - 1920, 280 - 1340 and 56 - 132 {mu}g kg-1 for T2, , fuminosin, Don and Zearalenone, respectively. Only 87% of the composite pelletted feed samples were contaminated with zearalenone, but all of theme were contaminated with various levels of the other three tested toxins. (author)

  1. The occurrence of Fusarium toxins (zearalenone, DON, fumonisin, and T2) in some food commodities and feedstuffs in Syria

    International Nuclear Information System (INIS)

    Ghanem, I.; Al-Arfe, M.

    2010-01-01

    The presence of four Fusarium toxins (namely, zearalenone, Don, fuminosin, and T2) was studied in 129 food commodities and feedstuff samples using an enzyme-linked immunosorbent assay (ELISA). Results showed that the percentages of wheat samples contaminated with T2, fuminosin, Don and Zearalenone were : 33%, 31%, 11.6% and 12.5% for each toxin, respectively. Concentrations of these toxins in the contaminated samples fell in the range of 81 - 350, 330 - 1330, 270 - 420 and 42-67 μg kg-1 for each toxin respectively. Barely samples showed higher percentages of contamination with those toxins amounting to 75.9%, 83.3%, 75% and 83.3% with concentrations ranging between 89-145, 270 - 1230, 650 - 3450 and 42-102 μg kg-1 for T2, , fuminosin, Don and Zearalenone, respectively. Percentages of contaminated bran samples were 80% for T2 and 100% for each of fumonisin, Don and zearalenone. Concentrations of T2, fuminosin, Don and Zearalenone in bran samples ranged between 81-322 , 510 - 1670 , 280 - 750 and 42-81 μg kg-1, respectively. All four tested toxins were present in corn samples. Levels of T2, , fuminosin, Don and Zearalenone in corn samples were in the range of 112-426 , 730 - 1820, 590 - 1080 and 63-112 μg kg-1, respectively. Similarly, 100% of examined soya seed cake samples were found contaminated with various levels of the four assayed toxins, with levels of contamination ranging between 98-142 , 1340 - 2220 , 330 - 800 and 93-114 μg kg-1, for T2, , fuminosin, Don and Zearalenone, respectively. All cotton seed cake samples were contaminated with the four tested toxins with contamination levels ranging between 94 - 142, 1120 - 1920, 280 - 1340 and 56 - 132 μg kg-1 for T2, , fuminosin, Don and Zearalenone, respectively. Only 87% of the composite pelletted feed samples were contaminated with zearalenone, but all of theme were contaminated with various levels of the other three tested toxins. (author)

  2. La visión fantasiosa/caballeresca de Don Quijote poco representada en la iconografía

    OpenAIRE

    Calabrese, Martín Ezequiel

    2017-01-01

    En el presente trabajo se analizará un aspecto un tanto curioso de la representación iconográfica del Quijote. En casi la totalidad de las ediciones de la obra se omite representar la “realidad” percibida por don Quijote, optando por graficar la representación realista de los hechos narrados. En los diferentes modelos iconográficos de las ediciones de la obra este aspecto es común, ya que ante el texto, la decisión habitual de los editores e ilustradores es mostrar a don Quijote como “es” den...

  3. The Influence of Processing by Impulse Pressure on the Productivity of the Don Barley (Hordeum vulgare L.

    Directory of Open Access Journals (Sweden)

    Pavlova Violetta Aleksandrovna

    2014-04-01

    Full Text Available Plant productivity is the important indicator, which determines the amount of yield. The productivity of plants depends on the number of bruchids per plant and on the weight of 1000 bruchids. The article studies the influence of impulse pressure of various magnitudes on plant productivity of Don barley (Hordeum vulgare L.. It was found that the pressure of 17 MPa was the most effective for increasing the productivity. Impulse pressure of other magnitudes also had influence on the productivity of Don barley.

  4. Libros adquiridos por don Pedro Fermín de Vargas en sus viajes por las Antillas

    Directory of Open Access Journals (Sweden)

    Sergio Elías Ortíz

    1962-04-01

    Full Text Available Entre los papeles relacionados con la vida de Don Pedro Fermín de Vargas, que pueden consultarse en el Archivo General de Indias de Sevilla, hay una carta de él y una lista de libros que envía al Administrador de Correos de la Habana, Don José Fuertes, antiguo amigo suyo, luego su corresponsal y a la  vez espía de sus pasos para aprisionarlo, con el objeto de que se los guardase “en algún rincón de sus casa”.

  5. Don Quixote, Sweded by Michel Gondry in Be Kind Rewind (2008

    Directory of Open Access Journals (Sweden)

    Hogan Erin K.

    2017-12-01

    Full Text Available In the spirit of poetic license from Be Kind Rewind (2008, this article argues that Michel Gondry’s film “swedes,” its playful neologism for ersatz remaking of Hollywood and classic films, Miguel de Cervantes’s Don Quixote. The feature follows the Sanchification of Jerry (Jack Black, Gondry’s Don Quixote, and Quixotification of Mike (Mos Def, Gondry’s Sancho, as they nostalgically wrong cinematic rights through sweding and try to save their working-class neighbourhood from condemnation and gentrification through community film making. Gondry swedes the Quixote through his engagement with major themes and operations in Cervantes’s classic, including nostalgia, story-telling, conflicts between reality and fantasy, authorship, the grotesque and carnivalesque, (anti-heroes, race and gender-bending, genre, and addressees turned addressers. This article discusses Be Kind Rewind’s relationship to Hollywoodian and Cervantine classics through the theoretical frameworks of Julio Garcia Espinosa’s imperfect cinema and Foucauldian semiotics, respectively. Be Kind Rewind uses and abuses Hollywood stereotypes to re-purpose them for a critique of discriminatory practices. Where casting is concerned and where Michel’s characters diverge from Miguel’s, Be Kind Rewind advances that skin colour is not an arbitrary sign and that race has historical and contemporary meaning in intercultural interactions.

  6. Homenaje a Don Gregorio Marañon en el Centenario de su Nacimiento

    Directory of Open Access Journals (Sweden)

    Fernando Serpa Florez

    1987-12-01

    Full Text Available

    La Academia Nacional de Medicina rinde homenaje hoy a un español universal, don Gregorio Marañón y Posadillo (1887-1960 en el primer centenario de su nacimiento. Se asocia a la admiración y al orgullo que este hombre despierta por su inteligencia, su sabiduría y su obra entre sus gentes de España, con el entrañable afecto que su nombre evoca entre nosotros los iberoamericanos que también, a nuestra manera, lo sentimos nuestro.

    Médico, historiador, escritor, humanista, sociólogo y maestro, su espíritu se ensoñoreó por los campos abiertos del saber, descollando con méritos señeros en cada una de estas disciplinas. Y si en el presente siglo su par en la medicina podría ser don Santiago Ramón y Cajal, en las letras don José Ortega y Gassety en las humanidades don Miguel de Unamuno, por su bucear en las aguas profundas y lustrales de la historia su nombre es parangonable con el de españoles eternos con los que equiparó su vida: un Séneca, por su austero interrogar al destino y por el doloroso regustar del destierro (“carere patria intolerabili est”. Un san Isidoro de Sevilla, por su ecumenismo. Un Garcilaso de la Vega, por su poético enamoramiento de Toledo. Un Maimónides, por las enseñanzas de su saber médico y por los discípulos dejados en las más diversas latitudes unido a su excepcional amplitud de criterio -rara flor en la patria de Ignacio de Loyolay de don Felipe 11-; ausencia de ese dogmatismo y fanatismo que el mismo “espejo de los caballeros” hubo de sublimar en las brumas de su locura para ser el arquetipo de lo español y de España. Y un Miguel Servet, en fin, por sus paralelas intuiciones científicas, las de éste en la circulación de la sangre pulmonar, las de don Gregario en la endocrinología, las hormonas y las muy sutiles investigaciones del hasta hace poco coto vedado de la sexología y los estados intersexuales.

    Corresponderá al distinguido representante de la Sociedad

  7. 'Don't play the butter notes': jazz in medical education.

    Science.gov (United States)

    Bradner, Melissa; Harper, Darryl V; Ryan, Mark H; Vanderbilt, Allison A

    2016-01-01

    Jazz has influenced world music and culture globally - attesting to its universal truths of surviving, enduring, and triumphing over tragedy. This begs the question, what can we glean in medical education from this philosophy of jazz mentoring? Despite our training to understand disease and illness in branching logic diagrams, the human experience of illness is still best understood when told as a story. Stories like music have tempos, pauses, and silences. Often they are not linear but wrap around the past, future, and back to the present, frustrating the novice and the experienced clinician in documenting the history of present illness. The first mentoring lesson Hancock discusses is from a time he felt stuck with his playing - his sound was routine. Miles Davis told him in a low husky murmur, 'Don't play the butter notes'. In medical education, 'don't play the butter notes' suggests not undervaluing the metacognition and reflective aspects of medical training that need to be fostered during the early years of clinical teaching years.

  8. Don Quixote, Machiavelli, and Robin Hood: public health practice, past and present.

    Science.gov (United States)

    Mullan, F

    2000-05-01

    Since the mid-19th century, when the first formal health departments were established in the United States, commissioners, directors, and secretaries of public health have functioned as senior members of the staffs of public executives, mayors, governors, and presidents. They have provided important political, managerial, and scientific leadership to agencies of government that have played increasingly important roles in national life, from the sanitary revolution of the 19th century to the prevention of HIV/AIDS and the control of tobacco use today. Although public health officials come from a variety of backgrounds and oversee agencies of varied size and composition, there are philosophical themes that describe and define the commonality of their work. These themes are captured metaphorically by 3 celebrated figures: Don Quixote, Machiavelli, and Robin Hood. By turns, the public health official functions as a determined idealist (Don Quixote), a cunning political strategist (Machiavelli), and an agent who redistributes resources from the wealthier sectors of society to the less well off (Robin Hood.) All 3 personae are important, but, it is argued, Robin Hood is the most endangered.

  9. When Marcel Mauss's Essai sur le Don becomes The Gift: variations on the theme of solidarity.

    Science.gov (United States)

    Bateman, Simone

    2016-12-01

    Since the early 1970s, Marcel Mauss's Essai sur le Don (1923), translated into English as The Gift in 1954, has been a standard reference in the social science and bioethical literature on the use of human body parts and substances for medical and research purposes. At that time, three social scientists-political scientist Richard Titmuss in the United Kingdom and sociologist Renée C. Fox working with historian Judith Swazey in the United States-had the idea of using this concept to highlight the fundamental structure of the biomedical practices they were studying, respectively, blood donation, and hemodialysis and organ transplantation. The fact that these first applications of Mauss's essay should emerge in English- rather than in French-speaking countries raises the question of what the translation of the essay, and notably of the word don as gift, may have to do with this fact. Reading Mauss in translation undoubtedly inspired a seminal approach to interpreting medical and research practices based on bodily giving. This article posits that something may have also been lost: a much broader concept of giving with unquestionable links to the Durkheimian concept of solidarity, which Mauss conceptualizes not only as an obligation but also as a liberty to give.

  10. Radiation biology for the non-biologist

    International Nuclear Information System (INIS)

    Myers, D.K.

    1978-06-01

    This colloquium introduces some of the general concepts used in cell biology and in the study of the effects of ionizing radiation on living organisms. The present research activities in radiation biology in the Biology Branch at the Chalk River Nuclear Laboratories cover a broad range of interests in the entire chain of events by which the initial radiation-induced changes in the living cell are translated into significant biological effects, including the eventual production of cancers and hereditary defects. The main theme of these research activities is an understanding of the mechanisms by which radiation damage to DNA (the carrier of hereditary information in all living organisms) can be actively repaired by the living cell. Advances in our understanding of these processes have broad implications for other areas of biology but also bear directly on the assessment of the biological hazards of ionizing radiation. The colloquium concludes with a brief discussion of the hazards of low-level radiation. (author)

  11. Biodiversities and habitabilities : a biologist view

    Science.gov (United States)

    Maurel, Marie-Christine

    2015-07-01

    If life were to again take the path it followed billion years ago, nobody can certify that it would take the same path, leading to the same species, the same types of cells, the same organisation. This implies that if life exists - or existed - elsewhere, benefiting from the same initial planetary conditions, it most likely does would not have the same history, or would not have followed the same itinerary. Thus, how can we possibly recognize and/or identify something new, probably completely new that we are unable to conceive and/or to conceptualize? From a materialistic point of view, there is no frontier between what is alive and what is not; this is a basic question for the biology community, mainly via the question of viruses and viroids. It is thus very ambiguous to define the meaning of biomarkers, and even more to search for life elsewhere based strictly on the observations of what we know occurs on Earth. Just as what is 'pathological' in biology provides us with an insight on what is 'normal', the space that lies at the border between the living and the non-living will maybe allow us to envisage other forms of life (that we cannot imagine to-day).

  12. Bringing LTL Model Checking to Biologists

    OpenAIRE

    Ahmed, Z; Benque, D; Berezin, S; Dahl, ACE; Fisher, Jasmin; Hall, Benjamin Andrew; Ishtiaq, S; Nanavati, J; Piterman, N; Riechert, M; Skoblov, N

    2017-01-01

    The BioModelAnalyzer (BMA) is a web based tool for the development of discrete models of biological systems. Through a graphical user interface, it allows rapid development of complex models of gene and protein interaction networks and stability analysis without requiring users to be proficient computer programmers. Whilst stability is a useful specification for testing many systems, testing temporal specifications in BMA presently requires the user to perform simulations. Here we describe th...

  13. Genetics of asthma: a molecular biologist perspective

    OpenAIRE

    Ghosh Balaram; Kumar Amrendra

    2009-01-01

    Abstract Asthma belongs to the category of classical allergic diseases which generally arise due to IgE mediated hypersensitivity to environmental triggers. Since its prevalence is very high in developed or urbanized societies it is also referred to as "disease of civilizations". Due to its increased prevalence among related individuals, it was understood quite long back that it is a genetic disorder. Well designed epidemiological studies reinforced these views. The advent of modern biologica...

  14. Interactive visualization tools for the structural biologist.

    Science.gov (United States)

    Porebski, Benjamin T; Ho, Bosco K; Buckle, Ashley M

    2013-10-01

    In structural biology, management of a large number of Protein Data Bank (PDB) files and raw X-ray diffraction images often presents a major organizational problem. Existing software packages that manipulate these file types were not designed for these kinds of file-management tasks. This is typically encountered when browsing through a folder of hundreds of X-ray images, with the aim of rapidly inspecting the diffraction quality of a data set. To solve this problem, a useful functionality of the Macintosh operating system (OSX) has been exploited that allows custom visualization plugins to be attached to certain file types. Software plugins have been developed for diffraction images and PDB files, which in many scenarios can save considerable time and effort. The direct visualization of diffraction images and PDB structures in the file browser can be used to identify key files of interest simply by scrolling through a list of files.

  15. The Live Universe. A Biologist's Perspective

    Directory of Open Access Journals (Sweden)

    Ricardo B. Ferreira

    2017-09-01

    Full Text Available Astrobiology looks at all aspects related to life in places other than the Earth, including its biomolecular building blocks and suitable environmental conditions. In the present article, a different approach is followed: a comparative analysis between Astronomy and Biology as discrete domains of science. Remarkable similarities exist between these two apparently widely separated and multidisciplinary fields. Both are driven, from beginning to end, by thermodynamics. Their evolution is studied to a very reasonable degree of accuracy, from beginning to the present day, by analyzing data which were “frozen” in the past. Yet we cannot predict where and how they will go from here. A major difference is that in Biology, unlike Astronomy, we can see and analyse the present (or, more accurately, the immediate past. While the Big Bang is widely accepted as the origin of our universe, the debate about its ultimate fate is far from settled. A plethora of cosmological models has been proposed, many involving the concept of a multiuniverse. The observation that the rate of expansion of the universe is apparently accelerating further boosts the discussion. Entropy may act as a driving force behind the increasing rate of expansion, with nothingness as the maximum possible entropy our universe gets. Using biological systems as an analogy and adopting a broad definition for life, we may speculate the existence of a living multiuniverse, capable of natural evolution, in which each individual universe spontaneously goes through birth, development, reproduction, aging and death. The possible roles of supermassive black holes (SMBHs and human-like intelligence on the future evolution of our universe are briefly discussed.

  16. Effects of Pinus flexilis on the dynamics and structure of plant communities on the northern Rocky Mountain front, and, Training biologists for emerging niches in non-traditional jobs

    Science.gov (United States)

    Baumeister, Dayna Marie

    been characterized by invasion of P. flexilis and subsequent shifts in understory species composition apparently facilitated by P. flexilis. Lastly, I examined the role of the emerging science of biomimicry in providing employment for biologists. Biomimicry as a discipline seeks design solutions inspired by nature. Industries employing this tool require biologists with an understanding of biology from a functional perspective, good communication skills, and a background in applied natural history.

  17. 77 FR 23673 - Notice of Stakeholder Meeting: Industry Roundtable-DON/USDA/DOE/DOT-FAA Advanced Drop-In Biofuels...

    Science.gov (United States)

    2012-04-20

    ...--DON/USDA/DOE/ DOT-FAA Advanced Drop-In Biofuels Initiative AGENCY: Department of the Navy, DoD. ACTION... participants in the biofuels supply chain. The purpose of the roundtable meeting is for the federal government... Biofuels Production Project. Questions related to the Special Notices or the pending Broad Agency...

  18. The Emperor Has No Clothes: Teaching about Race and Racism to People Who Don't Want to Know

    Science.gov (United States)

    Okun, Tema Jon

    2010-01-01

    "The Emperor Has No Clothes: Teaching About Race and Racism to People Who Don't Want to Know" is designed to offer both practical and theoretical grounding for leaders and teachers interested in effectively addressing racism as well as other oppressive constructs. The dissertation offers an overview of the role of western culture in maintaining…

  19. Fungsi Bangunan Dokwi Vam dan Kembu Vam Bagi Suku Yali dalam Novel Penguasa-penguasa Bumi Karya Don Richardson

    Directory of Open Access Journals (Sweden)

    Ummu Fatimah Ria Lestari

    2016-04-01

    Full Text Available This study discusses the function of the building of Dokwi Vam and Kembu Vam contained in the novel-Sovereign Ruler of the Earth works Don Richardson. In general, this novel tells the story of the life of Stan Dale and Yali tribe. Stan Dale is a missionary who served in Papua. He struggled to introduce Christianity to the Yali tribe. This study uses the description of the technical literature. This research resulted in a description of the function of the building of Dokwi Vam and Kembu Vam contained in the novel Lord of-Ruler of the Earth works Don Richardson. Dokwi Vam used as a museum (where the old stuff to worship as they still follow animism, while the Kembu Vam serves as a temple / animism worship in Yali tribe. Penelitian ini membahas tentang fungsi bangunan Dokwi Vam dan Kembu Vam yang terdapat dalam novel Penguasa-Penguasa Bumi karya Don Richardson. Secara umum, novel ini bercerita tentang kehidupan Stan Dale dan suku Yali. Stan Dale adalah seorang missionaris yang melayani di Tanah Papua. Ia berjuang untuk memperkenalkan agama Nasrani kepada suku Yali. Penelitian ini menggunakan metode deskripsi dengan teknik studi pustaka. Penelitian ini menghasilkan deskripsi tentang fungsi bangunan Dokwi Vam dan Kembu Vam yang terdapat dalam novel Penguasa-Penguasa Bumi karya Don Richardson. Dokwi Vam digunakan sebagai museum (tempat barang-barang kuno untuk penyembahan karena mereka masih menganut kepercayaan animisme, sedangkan Kembu Vam berfungsi sebagai rumah peribadatan/penyembahan dalam kepercayaan animisme suku Yali.

  20. Influencia de la poda en el desarrollo de masas de Pinus radiata D. Don y Pinus pinaster Aiton en Asturias

    OpenAIRE

    Hevia Cabal, Andrea

    2013-01-01

    Esta tesis evaluó la influencia de diferentes intensidades de poda sobre el crecimiento, desarrollo y persistencia de masas regulares jóvenes de Pinus radiata D. Don y Pinus pinaster Aiton en Asturias, dentro de una selvicultura sostenible enfocada a la producción de madera de calidad.