WorldWideScience

Sample records for biological warfare protection

  1. Biological warfare agents

    Directory of Open Access Journals (Sweden)

    Duraipandian Thavaselvam

    2010-01-01

    Full Text Available The recent bioterrorist attacks using anthrax spores have emphasized the need to detect and decontaminate critical facilities in the shortest possible time. There has been a remarkable progress in the detection, protection and decontamination of biological warfare agents as many instrumentation platforms and detection methodologies are developed and commissioned. Even then the threat of biological warfare agents and their use in bioterrorist attacks still remain a leading cause of global concern. Furthermore in the past decade there have been threats due to the emerging new diseases and also the re-emergence of old diseases and development of antimicrobial resistance and spread to new geographical regions. The preparedness against these agents need complete knowledge about the disease, better research and training facilities, diagnostic facilities and improved public health system. This review on the biological warfare agents will provide information on the biological warfare agents, their mode of transmission and spread and also the detection systems available to detect them. In addition the current information on the availability of commercially available and developing technologies against biological warfare agents has also been discussed. The risk that arise due to the use of these agents in warfare or bioterrorism related scenario can be mitigated with the availability of improved detection technologies.

  2. Biological warfare agents

    Science.gov (United States)

    Thavaselvam, Duraipandian; Vijayaraghavan, Rajagopalan

    2010-01-01

    The recent bioterrorist attacks using anthrax spores have emphasized the need to detect and decontaminate critical facilities in the shortest possible time. There has been a remarkable progress in the detection, protection and decontamination of biological warfare agents as many instrumentation platforms and detection methodologies are developed and commissioned. Even then the threat of biological warfare agents and their use in bioterrorist attacks still remain a leading cause of global concern. Furthermore in the past decade there have been threats due to the emerging new diseases and also the re-emergence of old diseases and development of antimicrobial resistance and spread to new geographical regions. The preparedness against these agents need complete knowledge about the disease, better research and training facilities, diagnostic facilities and improved public health system. This review on the biological warfare agents will provide information on the biological warfare agents, their mode of transmission and spread and also the detection systems available to detect them. In addition the current information on the availability of commercially available and developing technologies against biological warfare agents has also been discussed. The risk that arise due to the use of these agents in warfare or bioterrorism related scenario can be mitigated with the availability of improved detection technologies. PMID:21829313

  3. Technological advancements for the detection of and protection against biological and chemical warfare agents.

    Science.gov (United States)

    Eubanks, Lisa M; Dickerson, Tobin J; Janda, Kim D

    2007-03-01

    There is a growing need for technological advancements to combat agents of chemical and biological warfare, particularly in the context of the deliberate use of a chemical and/or biological warfare agent by a terrorist organization. In this tutorial review, we describe methods that have been developed both for the specific detection of biological and chemical warfare agents in a field setting, as well as potential therapeutic approaches for treating exposure to these toxic species. In particular, nerve agents are described as a typical chemical warfare agent, and the two potent biothreat agents, anthrax and botulinum neurotoxin, are used as illustrative examples of potent weapons for which countermeasures are urgently needed.

  4. Personal protection during resuscitation of casualties contaminated with chemical or biological warfare agents--a survey of medical first responders.

    Science.gov (United States)

    Brinker, Andrea; Prior, Kate; Schumacher, Jan

    2009-01-01

    The threat of mass casualties caused by an unconventional terrorist attack is a challenge for the public health system, with special implications for emergency medicine, anesthesia, and intensive care. Advanced life support of patients injured by chemical or biological warfare agents requires an adequate level of personal protection. The aim of this study was to evaluate the personal protection knowledge of emergency physicians and anesthetists who would be at the frontline of the initial health response to a chemical/biological warfare agent incident. After institutional review board approval, knowledge of personal protection measures among emergency medicine (n = 28) and anesthetics (n = 47) specialty registrars in the South Thames Region of the United Kingdom was surveyed using a standardized questionnaire. Participants were asked for the recommended level of personal protection if a chemical/biological warfare agent(s) casualty required advanced life support in the designated hospital resuscitation area. The best awareness within both groups was regarding severe acute respiratory syndrome, and fair knowledge was found regarding anthrax, plague, Ebola, and smallpox. In both groups, knowledge about personal protection requirements against chemical warfare agents was limited. Knowledge about personal protection measures for biological agents was acceptable, but was limited for chemical warfare agents. The results highlight the need to improve training and education regarding personal protection measures for medical first receivers.

  5. Expeditionary Warfare- Force Protection

    National Research Council Canada - National Science Library

    Higgins, Eric

    2004-01-01

    In 2003, the Systems Engineering and Analysis students were tasked to develop a system of systems conceptual solution to provide force protection for the Sea Base conceptualized in the 2002 Expeditionary Warfare study...

  6. Biological warfare, bioterrorism, and biocrime

    NARCIS (Netherlands)

    Jansen, H. J.; Breeveld, F. J.; Stijnis, C.; Grobusch, M. P.

    2014-01-01

    Biological weapons achieve their intended target effects through the infectivity of disease-causing infectious agents. The ability to use biological agents in warfare is prohibited by the Biological and Toxin Weapon Convention. Bioterrorism is defined as the deliberate release of viruses, bacteria

  7. Modified clay minerals efficiency against chemical and biological warfare agents for civil human protection.

    Science.gov (United States)

    Plachá, Daniela; Rosenbergová, Kateřina; Slabotínský, Jiří; Kutláková, Kateřina Mamulová; Studentová, Soňa; Martynková, Gražyna Simha

    2014-04-30

    Sorption efficiencies of modified montmorillonite and vermiculite of their mono ionic Na and organic HDTMA and HDP forms were studied against chemical and biological warfare agents such as yperite and selected bacterial strains. Yperite interactions with modified clay minerals were observed through its capture in low-density polyethylene foil-modified clay composites by measuring yperite gas permeation with using chemical indication and gas chromatography methods. The antibacterial activities of synthetized organoclays were tested against selected Gram-positive and Gram-negative bacterial species in minimum inhibitory concentration tests. The obtained results showed a positive influence of modified clay minerals on the significant yperite breakthrough-time increase. The most effective material was the polyethylene-Na form montmorillonite, while the polyethylene-Na form vermiculite showed the lowest efficiency. With increasing organic cations loading in the interlayer space the montmorillonite efficiency decreased, and in the case of vermiculite an opposite effect was observed. Generally the modified montmorillonites were more effective than modified vermiculites. The HDP cations seem to be more effective compare to the HDTMA. The antibacterial activity tests confirmed efficiency of all organically modified clay minerals against Gram-positive bacteria. The confirmation of antibacterial activity against Y. pestis, plague bacteria, is the most interesting result of this part of the study. Copyright © 2014 Elsevier B.V. All rights reserved.

  8. Biomaterials for mediation of chemical and biological warfare agents.

    Science.gov (United States)

    Russell, Alan J; Berberich, Jason A; Drevon, Geraldine F; Koepsel, Richard R

    2003-01-01

    Recent events have emphasized the threat from chemical and biological warfare agents. Within the efforts to counter this threat, the biocatalytic destruction and sensing of chemical and biological weapons has become an important area of focus. The specificity and high catalytic rates of biological catalysts make them appropriate for decommissioning nerve agent stockpiles, counteracting nerve agent attacks, and remediation of organophosphate spills. A number of materials have been prepared containing enzymes for the destruction of and protection against organophosphate nerve agents and biological warfare agents. This review discusses the major chemical and biological warfare agents, decontamination methods, and biomaterials that have potential for the preparation of decontamination wipes, gas filters, column packings, protective wear, and self-decontaminating paints and coatings.

  9. Biological warfare, bioterrorism, and biocrime.

    Science.gov (United States)

    Jansen, H J; Breeveld, F J; Stijnis, C; Grobusch, M P

    2014-06-01

    Biological weapons achieve their intended target effects through the infectivity of disease-causing infectious agents. The ability to use biological agents in warfare is prohibited by the Biological and Toxin Weapon Convention. Bioterrorism is defined as the deliberate release of viruses, bacteria or other agents used to cause illness or death in people, but also in animals or plants. It is aimed at creating casualties, terror, societal disruption, or economic loss, inspired by ideological, religious or political beliefs. The success of bioterroristic attempts is defined by the measure of societal disruption and panic, and not necessarily by the sheer number of casualties. Thus, making only a few individuals ill by the use of crude methods may be sufficient, as long as it creates the impact that is aimed for. The assessment of bioterrorism threats and motives have been described before. Biocrime implies the use of a biological agent to kill or make ill a single individual or small group of individuals, motivated by revenge or the desire for monetary gain by extortion, rather than by political, ideological, religious or other beliefs. The likelihood of a successful bioterrorist attack is not very large, given the technical difficulties and constraints. However, even if the number of casualties is likely to be limited, the impact of a bioterrorist attack can still be high. Measures aimed at enhancing diagnostic and therapeutic capabilities and capacities alongside training and education will improve the ability of society to combat 'regular' infectious diseases outbreaks, as well as mitigating the effects of bioterrorist attacks. © 2014 The Authors Clinical Microbiology and Infection © 2014 European Society of Clinical Microbiology and Infectious Diseases.

  10. Chemical and biological warfare. Should defenses be researched and deployed?

    Science.gov (United States)

    Orient, J M

    1989-08-04

    The threat of chemical and biological weapons of mass destruction has intensified because of improved delivery systems and advances in chemistry, genetics, and other sciences. Possible US responses to this threat include deterrence, defenses, and/or disarmament, including a reaffirmation of the Biological and Toxin Weapons Convention of 1972, which is now in jeopardy. This article discusses the history of chemical and biological warfare, existing and potential weapons, the proliferation of weapons and delivery systems, ways to prevent the use of these weapons, and ways to protect populations from their effects.

  11. Nuclear, biological and chemical warfare. Part I: Medical aspects of nuclear warfare.

    Science.gov (United States)

    Kasthuri, A S; Pradhan, A B; Dham, S K; Bhalla, I P; Paul, J S

    1990-04-01

    Casualties in earlier wars were due much more to diseases than to weapons. Mention has been made in history of the use of biological agents in warfare, to deny the enemy food and water and to cause disease. In the first world war chemical agents were used to cause mass casualties. Nuclear weapons were introduced in the second world war. Several countries are now involved in developing nuclear, biological and chemical weapon systems, for the mass annihilation of human beings, animals and plants, and to destroy the economy of their enemies. Recently, natural calamities and accidents in nuclear, chemical and biological laboratories and industries have caused mass instantaneous deaths in civilian population. The effects of future wars will not be restricted to uniformed persons. It is time that physicians become aware of the destructive potential of these weapons. Awareness, immediate protective measures and first aid will save a large number of persons. This series of articles will outline the medical aspects of nuclear, biological and chemical weapon systems in three parts. Part I will deal with the biological effects of a nuclear explosion. The short and long term effects due to blast, heat and associated radiation are highlighted. In Part II, the role of biological agents which cause commoner or new disease patterns is mentioned. Some of the accidents from biological warfare laboratories are a testimony to its potential deleterious effects. Part III deals with medical aspects of chemical warfare agents, which in view of their mass effects can overwhelm the existing medical resources, both civilian and military.(ABSTRACT TRUNCATED AT 250 WORDS)

  12. History of chemical and biological warfare agents

    International Nuclear Information System (INIS)

    Szinicz, L.

    2005-01-01

    Chemical and biological warfare agents constitute a low-probability, but high-impact risk both to the military and to the civilian population. The use of hazardous materials of chemical or biological origin as weapons and for homicide has been documented since ancient times. The first use of chemicals in terms of weapons of mass destruction goes back to World War I, when on April 22, 1915 large amounts of chlorine were released by German military forces at Ypres, Belgium. Until around the 1970s of the 20th century, the awareness of the threat by chemical and biological agents had been mainly confined to the military sector. In the following time, the development of increasing range delivery systems by chemical and biological agents possessors sensitised public attention to the threat emanating from these agents. Their proliferation to the terrorists field during the 1990s with the expanding scale and globalisation of terrorist attacks suggested that these agents are becoming an increasing threat to the whole world community. The following article gives a condensed overview on the history of use and development of the more prominent chemical and biological warfare agents

  13. History of chemical and biological warfare agents.

    Science.gov (United States)

    Szinicz, L

    2005-10-30

    Chemical and biological warfare agents constitute a low-probability, but high-impact risk both to the military and to the civilian population. The use of hazardous materials of chemical or biological origin as weapons and for homicide has been documented since ancient times. The first use of chemicals in terms of weapons of mass destruction goes back to World War I, when on April 22, 1915 large amounts of chlorine were released by German military forces at Ypres, Belgium. Until around the 1970s of the 20th century, the awareness of the threat by chemical and biological agents had been mainly confined to the military sector. In the following time, the development of increasing range delivery systems by chemical and biological agents possessors sensitised public attention to the threat emanating from these agents. Their proliferation to the terrorists field during the 1990s with the expanding scale and globalisation of terrorist attacks suggested that these agents are becoming an increasing threat to the whole world community. The following article gives a condensed overview on the history of use and development of the more prominent chemical and biological warfare agents.

  14. [Decontamination of chemical and biological warfare agents].

    Science.gov (United States)

    Seto, Yasuo

    2009-01-01

    Chemical and biological warfare agents (CBWA's) are diverse in nature; volatile acute low-molecular-weight toxic compounds, chemical warfare agents (CWA's, gaseous choking and blood agents, volatile nerve gases and blister agents, nonvolatile vomit agents and lacrymators), biological toxins (nonvolatile low-molecular-weight toxins, proteinous toxins) and microbes (bacteria, viruses, rickettsiae). In the consequence management against chemical and biological terrorism, speedy decontamination of victims, facilities and equipment is required for the minimization of the damage. In the present situation, washing victims and contaminated materials with large volumes of water is the basic way, and additionally hypochlorite salt solution is used for decomposition of CWA's. However, it still remains unsolved how to dispose large volumes of waste water, and the decontamination reagents have serious limitation of high toxicity, despoiling nature against the environments, long finishing time and non-durability in effective decontamination. Namely, the existing decontamination system is not effective, nonspecifically affecting the surrounding non-target materials. Therefore, it is the urgent matter to build up the usable decontamination system surpassing the present technologies. The symposiast presents the on-going joint project of research and development of the novel decontamination system against CBWA's, in the purpose of realizing nontoxic, fast, specific, effective and economical terrorism on-site decontamination. The projects consists of (1) establishment of the decontamination evaluation methods and verification of the existing technologies and adaptation of bacterial organophosphorus hydrolase, (2) development of adsorptive elimination technologies using molecular recognition tools, and (4) development of deactivation technologies using photocatalysis.

  15. Researchers study decontamination of chemical, biological warfare agents

    OpenAIRE

    Trulove, Susan

    2007-01-01

    The U.S. Army Research Office has awarded Virginia Tech a $680,000 grant over two years to build an instrument that can be used to study the chemistry of gases that will decompose both chemical and biological warfare agents on surfaces.

  16. Cutaneous reactions in nuclear, biological and chemical warfare

    Directory of Open Access Journals (Sweden)

    Arora Sandeep

    2005-03-01

    Full Text Available Nuclear, biological and chemical warfare have in recent times been responsible for an increasing number of otherwise rare dermatoses. Many nations are now maintaining overt and clandestine stockpiles of such arsenal. With increasing terrorist threats, these agents of mass destruction pose a risk to the civilian population. Nuclear and chemical attacks manifest immediately while biological attacks manifest later. Chemical and biological attacks pose a significant risk to the attending medical personnel. The large scale of anticipated casualties in the event of such an occurrence would need the expertise of all physicians, including dermatologists, both military and civilian. Dermatologists are uniquely qualified in this respect. This article aims at presenting a review of the cutaneous manifestations in nuclear, chemical and biological warfare and their management.

  17. Identification of the factors that govern the ability of therapeutic antibodies to provide postchallenge protection against botulinum toxin: a model for assessing postchallenge efficacy of medical countermeasures against agents of bioterrorism and biological warfare.

    Science.gov (United States)

    Al-Saleem, Fetweh H; Nasser, Zidoon; Olson, Rebecca M; Cao, Linsen; Simpson, Lance L

    2011-08-01

    Therapeutic antibodies are one of the major classes of medical countermeasures that can provide protection against potential bioweapons such as botulinum toxin. Although a broad array of antibodies are being evaluated for their ability to neutralize the toxin, there is little information that defines the circumstances under which these antibodies can be used. In the present study, an effort was made to quantify the temporal factors that govern therapeutic antibody use in a postchallenge scenario. Experiments were done involving inhalation administration of toxin to mice, intravenous administration to mice, and direct application to murine phrenic nerve-hemidiaphragm preparations. As part of this study, several pharmacokinetic characteristics of botulinum toxin and neutralizing antibodies were measured. The core observation that emerged from the work was that the window of opportunity within which postchallenge administration of antibodies exerted a beneficial effect increased as the challenge dose of toxin decreased. The critical factor in establishing the window of opportunity was the amount of time needed for fractional redistribution of a neuroparalytic quantum of toxin from the extraneuronal space to the intraneuronal space. This redistribution event was a dose-dependent phenomenon. It is likely that the approach used to identify the factors that govern postchallenge efficacy of antibodies against botulinum toxin can be used to assess the factors that govern postchallenge efficacy of medical countermeasures against any agent of bioterrorism or biological warfare.

  18. Development of Bicarbonate-Activated Peroxide as a Chemical and Biological Warfare Agent Decontaminant

    National Research Council Canada - National Science Library

    Richardson, David E

    2006-01-01

    ...) and other chemistry for the decontamination of chemical and biological warfare agents. The mechanism of formation of the active oxidant, peroxymonocarbonate, has been investigated in detail. New surfoxidants...

  19. Chemical and Biological Warfare: A Manageable Problem

    National Research Council Canada - National Science Library

    Donahoo, Brian

    2003-01-01

    ... (Desert Storm 1991 and Desert Storm 2003). The intent is to provide combat forces with a logical and realistic framework to accurately assess the CB threat enabling a proper balance of force protection and mission accomplishment...

  20. Nanoplatforms for Detection, Remediation and Protection Against Chem-Bio Warfare

    Science.gov (United States)

    Denkbaş, E. B.; Bayram, C.; Kavaz, D.; Çirak, T.; Demirbilek, M.

    Chemical and biological substances have been used as warfare agents by terrorists by varying degree of sophistication. It is critical that these agents be detected in real-time with high level of sensitively, specificity, and accuracy. Many different types of techniques and systems have been developed to detect these agents. But there are some limitations in these conventional techniques and systems. Limitations include the collection, handling and sampling procedures, detection limits, sample transfer, expensive equipment, personnel training, and detection materials. Due to the unique properties such as quantum effect, very high surface/volume ratio, enhanced surface reactivity, conductivity, electrical and magnetic properties of the nanomaterials offer great opportunity to develop very fast, sensitive, accurate and cost effective detection techniques and systems to detect chemical and biological (chem.-bio) warfare agents. Furthermore, surface modification of the materials is very easy and effective way to get functional or smart surfaces to be used as nano-biosensor platform. In that respect many different types of nanomaterials have been developed and used for the detection, remediation and protection, such as gold and silver nanoparticles, quantum dots, Nano chips and arrays, fluorescent polymeric and magnetic nanoparticles, fiber optic and cantilever based nanobiosensors, nanofibrillar nanostructures etc. This study summarizes preparation and characterization of nanotechnology based approaches for the detection of and remediation and protection against chem.-bio warfare agents.

  1. Protecting the United States Against Information Warfare

    Science.gov (United States)

    2000-04-01

    Information Systems Protection, An Invitation to a Dialogue, 2. ECommerce , "Business to Business to Consumer, Transaction Enabled Internet Solutions," n.d...available from <http://www.cplus.net/ ecommerce /estats.html>; Internet; accessed 7 February 2000. 7 Clinton, Defending America’s Cyberspace... ECommerce . "Business to Business to Consumer, Transaction Enabled Internet Solutions." n.d. Available from < http://www.cplus.net/ ecommerce

  2. Decontamination of biological warfare agents by a microwave plasma torch

    International Nuclear Information System (INIS)

    Lai, Wilson; Lai, Henry; Kuo, Spencer P.; Tarasenko, Olga; Levon, Kalle

    2005-01-01

    A portable arc-seeded microwave plasma torch running stably with airflow is described and applied for the decontamination of biological warfare agents. Emission spectroscopy of the plasma torch indicated that this torch produced an abundance of reactive atomic oxygen that could effectively oxidize biological agents. Bacillus cereus was chosen as a simulant of Bacillus anthracis spores for biological agent in the decontamination experiments. Decontamination was performed with the airflow rate of 0.393 l/s, corresponding to a maximum concentration of atomic oxygen produced by the torch. The experimental results showed that all spores were killed in less than 8 s at 3 cm distance, 12 s at 4 cm distance, and 16 s at 5 cm distance away from the nozzle of the torch

  3. Cybersecurity protecting critical infrastructures from cyber attack and cyber warfare

    CERN Document Server

    Johnson, Thomas A

    2015-01-01

    The World Economic Forum regards the threat of cyber attack as one of the top five global risks confronting nations of the world today. Cyber attacks are increasingly targeting the core functions of the economies in nations throughout the world. The threat to attack critical infrastructures, disrupt critical services, and induce a wide range of damage is becoming more difficult to defend against. Cybersecurity: Protecting Critical Infrastructures from Cyber Attack and Cyber Warfare examines the current cyber threat landscape and discusses the strategies being used by governments and corporatio

  4. Chemical warfare protection for the cockpit of future aircraft

    Science.gov (United States)

    Pickl, William C.

    1988-01-01

    Currently systems are being developed which will filter chemical and biological contaminants from crew station air. In order to maximize the benefits of these systems, a method of keeping the cockpit contaminant free during pilot ingress and egress is needed. One solution is to use a rectangular plastic curtain to seal the four edges of the canopy frame to the canopy sill. The curtain is stored in a tray which is recessed into the canopy sill and unfolds in accordion fashion as the canopy is raised. A two way zipper developed by Calspan could be used as an airlock between the pilot's oversuit and the cockpit. This system eliminates the pilot's need for heavy and restrictive CB gear because he would never be exposed to the chemical warfare environment.

  5. A new General Purpose Decontamination System for Chemical and Biological Warfare and Terrorism Agents

    National Research Council Canada - National Science Library

    Khetan, Sushil; Banerjee, xdDeboshri; Chanda, Arani; Collins, Terry

    2003-01-01

    Partial contents: Fe-TAML Activator of Peroxide,Activators of Hydrogen peroxide,Biological Warfare Agents,Bacterial Endospore,Bacterial Spore Deactivation,Modeling Studies,Deactivation Studies with Bacillus spores...

  6. Detection of biological warfare agents using ultra violet-laser induced fluorescence LIDAR.

    Science.gov (United States)

    Joshi, Deepti; Kumar, Deepak; Maini, Anil K; Sharma, Ramesh C

    2013-08-01

    This review has been written to highlight the threat of biological warfare agents, their types and detection. Bacterial biological agent Bacillus anthracis (bacteria causing the disease anthrax) which is most likely to be employed in biological warfare is being discussed in detail. Standoff detection of biological warfare agents in aerosol form using Ultra violet-Laser Induced Fluorescence (UV-LIF) spectroscopy method has been studied. Range-resolved detection and identification of biological aerosols by both nano-second and non-linear femto-second LIDAR is also discussed. Calculated received fluorescence signal for a cloud of typical biological agent Bacillus globigii (Simulants of B. anthracis) at a location of ~5.0 km at different concentrations in presence of solar background radiation has been described. Overview of current research efforts in internationally available working UV-LIF LIDAR systems are also mentioned briefly. Copyright © 2013 Elsevier B.V. All rights reserved.

  7. PERMANENCE OF BIOLOGICAL AND CHEMICAL WARFARE AGENTS IN MUNICIPAL SOLID WASTE LANDFILL LEACHATES

    Science.gov (United States)

    The objective of this work is to permit EPA/ORD's National Homeland Security Research Center (NHSRC) and Edgewood Chemical Biological Center to collaborate together to test the permanence of biological and chemical warfare agents in municipal solid waste landfills. Research into ...

  8. The United States and biological warfare: secrets from the early cold war and Korea.

    Science.gov (United States)

    Bruwer, A

    2001-01-01

    The United States and Biological Warfare is about accusations that the United States resorted to bacteriological warfare at a time of great military stress during the Korean War. In December 1951, the then US Secretary of Defense ordered early readiness for offensive use of biological weapons. Soon afterwards, the North Korean and Chinese armies accused the United States of starting a large-scale biological warfare experiment in Korea. The US State Department denied the accusation. Both parties to the dispute maintain their positions today. The authors spent 20 years researching the accusations in North America, Europe and Japan. They were the first foreigners to be given access to Chinese classified documents. The reader is also introduced to the concept of 'plausible denial', an official US policy which allowed responsible governmental representatives to deny knowledge of certain events. The authors hope that their work will contribute to the understanding of a time when modern war expanded into a new type of violence.

  9. Mass spectrometry in identification of ecotoxicants including chemical and biological warfare agents

    International Nuclear Information System (INIS)

    Lebedev, Albert T.

    2005-01-01

    Mass spectrometry is a unique tool to detect and identify trace levels of organic and bioorganic compounds as well as microorganisms in the environment. The range of potential chemical warfare (CW) and biological warfare (BW) agents is very broad. An important advantage of mass spectrometry over other techniques involves potential for full spectrum detection of chemical and biological agents including mid-spectrum materials (i.e. bioactive peptides, toxins, etc.) for which biological approaches are inadequate. Being very fast (seconds and minutes), extremely sensitive (zeptomoles 10 -21 ), and informative (detailed qualitative and quantitative composition of mixtures containing hundreds of chemicals), mass spectrometry is a principal analytical tool at the sites of destruction of CW. Due to its unique features, mass spectrometry is applied not only for the detection of CW agents, but for the analysis of products of metabolism and degradation of these agents in organisms or environment as well. The present paper deals with some examples of successful application of mass spectrometry for the analyses of ecotoxicants, chemical warfare agents, explosives, and microorganisms including biology warfare agents

  10. Oxidative decontamination of chemical and biological warfare agents using L-Gel.

    Science.gov (United States)

    Raber, Ellen; McGuire, Raymond

    2002-08-05

    A decontamination method has been developed using a single reagent that is effective both against chemical warfare (CW) and biological warfare (BW) agents. The new reagent, "L-Gel", consists of an aqueous solution of a mild commercial oxidizer, Oxone, together with a commercial fumed silica gelling agent, Cab-O-Sil EH-5. L-Gel is non-toxic, environmentally friendly, relatively non-corrosive, maximizes contact time because of its thixotropic nature, clings to walls and ceilings, and does not harm carpets or painted surfaces. The new reagent also addresses the most demanding requirements for decontamination in the civilian sector, including availability, low maintenance, ease of application and deployment by a variety of dispersal mechanisms, minimal training and acceptable expense. Experiments to test the effectiveness of L-Gel were conducted at Lawrence Livermore National Laboratory and independently at four other locations. L-Gel was tested against all classes of chemical warfare agents and against various biological warfare agent surrogates, including spore-forming bacteria and non-virulent strains of real biological agents. Testing showed that L-Gel is as effective against chemical agents and biological materials, including spores, as the best military decontaminants.

  11. Analysis of the Threat of Genetically Modified Organisms for Biological Warfare

    Science.gov (United States)

    2011-05-01

    biological warfare. The primary focus of the framework are those aspects of the technology directly affecting humans by inducing virulent infectious disease...applications. Simple organisms such as fruit flies have been used to study the effects of genetic changes across generations. Transgenic mice are...Analysis * Multi-cell pathogens * Toxins (Chemical products of living cells.) * Fungi (Robust organism; no genetic manipulation needed

  12. Programme Biology - Health protection

    International Nuclear Information System (INIS)

    1975-01-01

    The scientific results for 1975, of the five-year Biology-Health Protection programme adopted in 1971, are presented in two volumes. In volume one, Research in Radiation Protection are developed exclusively, including the following topics: measurement and interpretation of radiation (dosimetry); transfer of radioactive nuclides in the constituents of the environment; hereditary effects of radiation; short-term effects (acute irradiation syndrome and its treatment); long-term effects and toxicology of radioactive elements. In volume, two Research on applications in Agriculture and Medicine are developed. It includes: mutagenesis; soil-plant relations; radiation analysis; food conservation; cell culture; radioentomology. Research on applications in Medicine include: Nuclear Medicine and Neutron Dosimetry

  13. Decontamination issues for chemical and biological warfare agents: how clean is clean enough?

    Science.gov (United States)

    Raber, E; Jin, A; Noonan, K; McGuire, R; Kirvel, R D

    2001-06-01

    The objective of this assessment is to determine what level of cleanup will be required to meet regulatory and stakeholder needs in the case of a chemical and/or biological incident at a civilian facility. A literature review for selected, potential chemical and biological warfare agents shows that dose information is often lacking or controversial. Environmental regulatory limits or other industrial health guidelines that could be used to help establish cleanup concentration levels for such agents are generally unavailable or not applicable for a public setting. Although dose information, cleanup criteria, and decontamination protocols all present challenges to effective planning, several decontamination approaches are available. Such approaches should be combined with risk-informed decision making to establish reasonable cleanup goals for protecting health, property, and resources. Key issues during a risk assessment are to determine exactly what constitutes a safety hazard and whether decontamination is necessary or not for a particular scenario. An important conclusion is that cleanup criteria are site dependent and stakeholder specific. The results of a modeling exercise for two outdoor scenarios are presented to reinforce this conclusion. Public perception of risk to health, public acceptance of recommendations based on scientific criteria, political support, time constraints, and economic concerns must all be addressed in the context of a specific scenario to yield effective and acceptable decontamination.

  14. Simulated experiment for elimination of chemical and biological warfare agents by making use of microwave plasma torch

    International Nuclear Information System (INIS)

    Hong, Yong C.; Kim, Jeong H.; Uhm, Han S.

    2004-01-01

    The threat of chemical and biological warfare agents in a domestic terrorist attack and in military conflict is increasing worldwide. Elimination and decontamination of chemical and biological warfare (CBW) agents are immediately required after such an attack. Simulated experiment for elimination of CBW agents by making use of atmospheric-pressure microwave plasma torches is carried out. Elimination of biological warfare agents indicated by the vitrification or burnout of sewage sludge powders and decomposition of toluene gas as a chemical agent stimulant are presented. A detailed characterization for the elimination of the simulant chemicals using Fourier transform infrared and gas chromatography is also presented

  15. Simulated experiment for elimination of chemical and biological warfare agents by making use of microwave plasma torch

    Science.gov (United States)

    Hong, Yong C.; Kim, Jeong H.; Uhm, Han S.

    2004-02-01

    The threat of chemical and biological warfare agents in a domestic terrorist attack and in military conflict is increasing worldwide. Elimination and decontamination of chemical and biological warfare (CBW) agents are immediately required after such an attack. Simulated experiment for elimination of CBW agents by making use of atmospheric-pressure microwave plasma torches is carried out. Elimination of biological warfare agents indicated by the vitrification or burnout of sewage sludge powders and decomposition of toluene gas as a chemical agent stimulant are presented. A detailed characterization for the elimination of the simulant chemicals using Fourier transform infrared and gas chromatography is also presented.

  16. Plasma flame for mass purification of contaminated air with chemical and biological warfare agents

    International Nuclear Information System (INIS)

    Uhm, Han S.; Shin, Dong H.; Hong, Yong C.

    2006-01-01

    An elimination of airborne simulated chemical and biological warfare agents was carried out by making use of a plasma flame made of atmospheric plasma and a fuel-burning flame, which can purify the interior air of a large volume in isolated spaces such as buildings, public transportation systems, and military vehicles. The plasma flame generator consists of a microwave plasma torch connected in series to a fuel injector and a reaction chamber. For example, a reaction chamber, with the dimensions of a 22 cm diameter and 30 cm length, purifies an airflow rate of 5000 lpm contaminated with toluene (the simulated chemical agent) and soot from a diesel engine (the simulated aerosol for biological agents). Large volumes of purification by the plasma flame will free mankind from the threat of airborne warfare agents. The plasma flame may also effectively purify air that is contaminated with volatile organic compounds, in addition to eliminating soot from diesel engines as an environmental application

  17. Chemical warfare agents

    Directory of Open Access Journals (Sweden)

    Vijayaraghavan R

    2010-01-01

    Full Text Available Among the Weapons of Mass Destruction, chemical warfare (CW is probably one of the most brutal created by mankind in comparison with biological and nuclear warfare. Chemical weapons are inexpensive and are relatively easy to produce, even by small terrorist groups, to create mass casualties with small quantities. The characteristics of various CW agents, general information relevant to current physical as well as medical protection methods, detection equipment available and decontamination techniques are discussed in this review article. A brief note on Chemical Weapons Convention is also provided.

  18. Chemical warfare agents

    Science.gov (United States)

    Ganesan, K.; Raza, S. K.; Vijayaraghavan, R.

    2010-01-01

    Among the Weapons of Mass Destruction, chemical warfare (CW) is probably one of the most brutal created by mankind in comparison with biological and nuclear warfare. Chemical weapons are inexpensive and are relatively easy to produce, even by small terrorist groups, to create mass casualties with small quantities. The characteristics of various CW agents, general information relevant to current physical as well as medical protection methods, detection equipment available and decontamination techniques are discussed in this review article. A brief note on Chemical Weapons Convention is also provided. PMID:21829312

  19. Developmental Testing of Liquid and Gaseous/Vaporous Decontamination on Bacterial Spores and Other Biological Warfare Agents on Military Relevant Surfaces

    Science.gov (United States)

    2016-02-11

    Vaporous Decontamination on Bacterial Spores and Other Biological Warfare Agents on Military-Relevant Surfaces 5a. CONTRACT NUMBER 5b. GRANT... DECONTAMINATION ON BACTERIAL SPORES AND OTHER BIOLOGICAL WARFARE AGENTS ON MILITARY-RELEVANT SURFACES Page Paragraph 1. SCOPE...surfaces before and after decontamination . The protocol in this TOP is based on the developed test methodologies from Edgewood Chemical Biological

  20. Bioterrorism and Biological Warfare, from Past to the Present: A classic review

    Directory of Open Access Journals (Sweden)

    Majid Zare Bidaki

    2015-10-01

    Full Text Available Bioterrorism is defined as any terrorist action of intentional release or dissemination of highly pathogenic biological agents, including a variety of microorganisms or biological toxins. With the growing threat of terrorism, is necessary that the potential danger of various microorganisms – as a powerful tool of aggression and threat- to be taken seriously. This review tries to explain the concept of biological weapons and their historical development process with an emphasis on efforts to control the proliferation of these types of weapons over the last century. Potential impact of infectious diseases on people and armed forces was known from since 600 BC. Using the victims of the plague as a weapon in medieval warfare and spread of smallpox as a weapon during the war against the Indians when initially America was discovered, the development of biological weapons during the World War I, World War II and the Cold War, and even since the beginning of the third millennium, all show the strategic importance of pathogenic microorganisms as a deterrent power for the superiority of some governments and cults. Historical attempts to use infectious diseases as biological weapons reveal that the distinction between a natural outbreak of an infectious disease and that of a deliberate biological attack is very difficult. Abusing this characteristic of infectious diseases has made it possible for the purposes of superiority. International agreements to control the development of biological weapons, such as “the 1925 Geneva Protocol” and “the Convention on the Prohibition of the Development, Production and Stockpiling of Biological and Toxic Weapons” have not been able to control the development and using of biological warfare.  The current paper is a classic review (Overview article aiming at increasing the knowledge and awareness of people especially of health authorities and government officials.

  1. Chemical warfare agent and biological toxin-induced pulmonary toxicity: could stem cells provide potential therapies?

    Science.gov (United States)

    Angelini, Daniel J; Dorsey, Russell M; Willis, Kristen L; Hong, Charles; Moyer, Robert A; Oyler, Jonathan; Jensen, Neil S; Salem, Harry

    2013-01-01

    Chemical warfare agents (CWAs) as well as biological toxins present a significant inhalation injury risk to both deployed warfighters and civilian targets of terrorist attacks. Inhalation of many CWAs and biological toxins can induce severe pulmonary toxicity leading to the development of acute lung injury (ALI) as well as acute respiratory distress syndrome (ARDS). The therapeutic options currently used to treat these conditions are very limited and mortality rates remain high. Recent evidence suggests that human stem cells may provide significant therapeutic options for ALI and ARDS in the near future. The threat posed by CWAs and biological toxins for both civilian populations and military personnel is growing, thus understanding the mechanisms of toxicity and potential therapies is critical. This review will outline the pulmonary toxic effects of some of the most common CWAs and biological toxins as well as the potential role of stem cells in treating these types of toxic lung injuries.

  2. NATO Advanced Research Workshop on Fluorescence and other Optical Properties of Biological Particles for Biological Warfare Agent Sensors

    CERN Document Server

    Hoekstra, Alfons; Videen, Gorden; Optics of Biological Particles

    2007-01-01

    This book covers the optics of single biological particles, both theory and experiment, with emphasis on Elastic Light Scattering and Fluorescence. It deals with the optics of bacteria (bio-aerosols), marine particles (selected phytoplankton communities) and red and white blood cells. Moreover, there are dedicated chapters on a general theory for scattering by a cell, and modelling and simulation of scattering by inhomogeneous biological cells. Finally, one chapter is dedicated to astro-biological signatures, discussing the possibilities for detecting non-terrestrial biological material. The volume has up-to-date discussions on new experimental and numerical techniques, and many examples of applications of these techniques in real-life systems, as used to detect and characterize e.g. biological warfare agents or human blood cells.

  3. Warfare and wildlife declines in Africa's protected areas.

    Science.gov (United States)

    Daskin, Joshua H; Pringle, Robert M

    2018-01-18

    Large-mammal populations are ecological linchpins, and their worldwide decline and extinction disrupts many ecosystem functions and services. Reversal of this trend will require an understanding of the determinants of population decline, to enable more accurate predictions of when and where collapses will occur and to guide the development of effective conservation and restoration policies. Many correlates of large-mammal declines are known, including low reproductive rates, overhunting, and habitat destruction. However, persistent uncertainty about the effects of one widespread factor-armed conflict-complicates conservation-planning and priority-setting efforts. Case studies have revealed that conflict can have either positive or negative local impacts on wildlife, but the direction and magnitude of its net effect over large spatiotemporal scales have not previously been quantified. Here we show that conflict frequency predicts the occurrence and severity of population declines among wild large herbivores in African protected areas from 1946 to 2010. Conflict was extensive during this period, occurring in 71% of protected areas, and conflict frequency was the single most important predictor of wildlife population trends among the variables that we analysed. Population trajectories were stable in peacetime, fell significantly below replacement with only slight increases in conflict frequency (one conflict-year per two-to-five decades), and were almost invariably negative in high-conflict sites, both in the full 65-year dataset and in an analysis restricted to recent decades (1989-2010). Yet total population collapse was infrequent, indicating that war-torn faunas can often recover. Human population density was also correlated (positively) with wildlife population trajectories in recent years; however, we found no significant effect, in either timespan, of species body mass, protected-area size, conflict intensity (human fatalities), drought frequency, presence of

  4. Functionalized polymer nanofibre membranes for protection from chemical warfare stimulants

    International Nuclear Information System (INIS)

    Ramaseshan, Ramakrishnan; Sundarrajan, Subramanian; Liu, Yingjun; Barhate, R S; Lala, Neeta L; Ramakrishna, S

    2006-01-01

    A catalyst for the detoxification of nerve agents is synthesized from β-cyclodextrin (β-CD) and o-iodosobenzoic acid (IBA). Functionalized polymer nanofibre membranes from PVC polymer are fabricated with β-CD, IBA, a blend of β-CD+IBA, and the synthesized catalyst. These functionalized nanofibres are then tested for the decontamination of paraoxon, a nerve agent stimulant, and it is observed that the stimulant gets hydrolysed. The kinetics of hydrolysis is investigated using UV spectroscopy. The rates of hydrolysis for different organophosphate hydrolyzing agents are compared. The reactivity and amount of adsorption of these catalysts are of higher capacity than the conventionally used activated charcoal. A new design for protective wear is proposed based on the functionalized nanofibre membrane

  5. Functionalized polymer nanofibre membranes for protection from chemical warfare stimulants

    Science.gov (United States)

    Ramaseshan, Ramakrishnan; Sundarrajan, Subramanian; Liu, Yingjun; Barhate, R. S.; Lala, Neeta L.; Ramakrishna, S.

    2006-06-01

    A catalyst for the detoxification of nerve agents is synthesized from β-cyclodextrin (β-CD) and o-iodosobenzoic acid (IBA). Functionalized polymer nanofibre membranes from PVC polymer are fabricated with β-CD, IBA, a blend of β-CD+IBA, and the synthesized catalyst. These functionalized nanofibres are then tested for the decontamination of paraoxon, a nerve agent stimulant, and it is observed that the stimulant gets hydrolysed. The kinetics of hydrolysis is investigated using UV spectroscopy. The rates of hydrolysis for different organophosphate hydrolyzing agents are compared. The reactivity and amount of adsorption of these catalysts are of higher capacity than the conventionally used activated charcoal. A new design for protective wear is proposed based on the functionalized nanofibre membrane.

  6. Functionalized polymer nanofibre membranes for protection from chemical warfare stimulants

    Energy Technology Data Exchange (ETDEWEB)

    Ramaseshan, Ramakrishnan [Nanoscience and Nanotechnology Initiative, National University of Singapore, 2 Engineering Drive 3, Singapore 117576, Singapore (Singapore); Sundarrajan, Subramanian [Nanoscience and Nanotechnology Initiative, National University of Singapore, 2 Engineering Drive 3, Singapore 117576, Singapore (Singapore); Liu, Yingjun [Department of Mechanical Engineering, National University of Singapore, 9 Engineering Drive 1, Singapore 117576, Singapore (Singapore); Barhate, R S [Nanoscience and Nanotechnology Initiative, National University of Singapore, 2 Engineering Drive 3, Singapore 117576, Singapore (Singapore); Lala, Neeta L [Nanoscience and Nanotechnology Initiative, National University of Singapore, 2 Engineering Drive 3, Singapore 117576, Singapore (Singapore); Ramakrishna, S [Nanoscience and Nanotechnology Initiative, National University of Singapore, 2 Engineering Drive 3, Singapore 117576, Singapore (Singapore)

    2006-06-28

    A catalyst for the detoxification of nerve agents is synthesized from {beta}-cyclodextrin ({beta}-CD) and o-iodosobenzoic acid (IBA). Functionalized polymer nanofibre membranes from PVC polymer are fabricated with {beta}-CD, IBA, a blend of {beta}-CD+IBA, and the synthesized catalyst. These functionalized nanofibres are then tested for the decontamination of paraoxon, a nerve agent stimulant, and it is observed that the stimulant gets hydrolysed. The kinetics of hydrolysis is investigated using UV spectroscopy. The rates of hydrolysis for different organophosphate hydrolyzing agents are compared. The reactivity and amount of adsorption of these catalysts are of higher capacity than the conventionally used activated charcoal. A new design for protective wear is proposed based on the functionalized nanofibre membrane.

  7. Love-Wave Sensors Combined with Microfluidics for Fast Detection of Biological Warfare Agents

    Directory of Open Access Journals (Sweden)

    Daniel Matatagui

    2014-07-01

    Full Text Available The following paper examines a time-efficient method for detecting biological warfare agents (BWAs. The method is based on a system of a Love-wave immunosensor combined with a microfluidic chip which detects BWA samples in a dynamic mode. In this way a continuous flow-through of the sample is created, promoting the reaction between antigen and antibody and allowing a fast detection of the BWAs. In order to prove this method, static and dynamic modes have been simulated and different concentrations of BWA simulants have been tested with two immunoreactions: phage M13 has been detected using the mouse monoclonal antibody anti-M13 (AM13, and the rabbit immunoglobulin (Rabbit IgG has been detected using the polyclonal antibody goat anti-rabbit (GAR. Finally, different concentrations of each BWA simulants have been detected with a fast response time and a desirable level of discrimination among them has been achieved.

  8. Insect-gene-activity detection system for chemical and biological warfare agents and toxic industrial chemicals

    Science.gov (United States)

    Mackie, Ryan S.; Schilling, Amanda S.; Lopez, Arturo M.; Rayms-Keller, Alfredo

    2002-02-01

    Detection of multiple chemical and biological weapons (CBW) agents and/or complex mixtures of toxic industrial chemicals (TIC) is imperative for both the commercial and military sectors. In a military scenario, a multi-CBW attack would create confusion, thereby delaying decontamination and therapeutic efforts. In the commercial sector, polluted sites invariably contain a mixture of TIC. Novel detection systems capable of detecting CBW and TIC are sorely needed. While it may be impossible to build a detector capable of discriminating all the possible combinations of CBW, a detection system capable of statistically predicting the most likely composition of a given mixture is within the reach of current emerging technologies. Aquatic insect-gene activity may prove to be a sensitive, discriminating, and elegant paradigm for the detection of CBW and TIC. We propose to systematically establish the expression patterns of selected protein markers in insects exposed to specific mixtures of chemical and biological warfare agents to generate a library of biosignatures of exposure. The predicting capabilities of an operational library of biosignatures of exposures will allow the detection of emerging novel or genetically engineered agents, as well as complex mixtures of chemical and biological weapons agents. CBW and TIC are discussed in the context of war, terrorism, and pollution.

  9. Applied radiation biology and protection

    International Nuclear Information System (INIS)

    Granier, R.; Gambini, D.-J.

    1990-01-01

    This book grew out of a series of courses in radiobiology and radiation protection which were given to students in schools for radiology technicians, radiation safety officers and to medical students. Topics covered include the sources of ionizing radiation and their interactions with matter; the detection and measurement of ionizing radiation; dosimetry; the biological effects of ionizing radiation; the effects of ionizing radiation on the human body; natural radioexposure; medical radio-exposure; industrial radioexposure of electronuclear origin; radioexposure due to experimental nuclear explosions; radiation protection; and accidents with external and/or internal radio-exposure. (UK)

  10. Applied radiation biology and protection

    International Nuclear Information System (INIS)

    Granier, R.; Gambini, D.J.

    1990-01-01

    Written by two eminent expects in the field with many years of teaching experience between them, this book presents a concise coverage of the physical and biological basics of radiation biology and protection. The book begins with a description of the methods of particle detection and dosimetric evaluation. The effects of ionizing radiation on man are treated from the initial physico-chemical phase of interaction to their conceivable pathological consequences. Regulations, limits and safeguards on nuclear power plants, radioisotope installations and medical centers which make use of ionizing radiation are given and the risks of exposure to natural, industrial and scientific radiation sources evaluated. The final chapter takes a look at some of the more important nuclear accidents, including Windscale, Three Mile Island, and Chernobyl, and describes basic procedures to be carried out in the eventuality of a nuclear emergency. Twelve chapters have been processed separately for inclusion in the appropriate data bases

  11. Effects of lactoferrin derived peptides on simulants of biological warfare agents.

    Science.gov (United States)

    Sijbrandij, Tjitske; Ligtenberg, Antoon J; Nazmi, Kamran; Veerman, Enno C I; Bolscher, Jan G M; Bikker, Floris J

    2017-01-01

    Lactoferrin (LF) is an important immune protein in neutrophils and secretory fluids of mammals. Bovine LF (bLF) harbours two antimicrobial stretches, lactoferricin and lactoferampin, situated in close proximity in the N1 domain. To mimic these antimicrobial domain parts a chimeric peptide (LFchimera) has been constructed comprising parts of both stretches (LFcin17-30 and LFampin265-284). To investigate the potency of this construct to combat a set of Gram positive and Gram negative bacteria which are regarded as simulants for biological warfare agents, the effect on bacterial killing, membrane permeability and membrane polarity were determined in comparison to the constituent peptides and the native bLF. Furthermore we aimed to increase the antimicrobial potency of the bLF derived peptides by cationic amino acid substitutions. Overall, the bactericidal activity of the peptides could be related to membrane disturbing effects, i.e. membrane permeabilization and depolarization. Those effects were most prominent for the LFchimera. Arginine residues were found to be crucial for displaying antimicrobial activity, as lysine to arginine substitutions resulted in an increased antimicrobial activity, affecting mostly LFampin265-284 whereas arginine to lysine substitutions resulted in a decreased bactericidal activity, predominantly in case of LFcin17-30.

  12. Isolation and expression of recombinant antibody fragments to the biological warfare pathogen Brucella melitensis.

    Science.gov (United States)

    Hayhurst, Andrew; Happe, Scott; Mabry, Robert; Koch, Zephyr; Iverson, Brent L; Georgiou, George

    2003-05-01

    Brucella melitensis is a highly infectious animal pathogen able to cause a recurring debilitating disease in humans and is therefore high on the list of biological warfare agents. Immunoglobulin genes from mice immunized with gamma-irradiated B. melitensis strain 16M were used to construct a library that was screened by phage display against similarly prepared bacteria. The selected phage particles afforded a strong enzyme-linked immunosorbent assay (ELISA) signal against gamma-irradiated B. melitensis cells. However, extensive efforts to express the respective single chain antibody variable region fragment (scFv) in soluble form failed due to: (i) poor solubility and (ii) in vivo degradation of the c-myc tag used for the detection of the recombinant antibodies. Both problems could be addressed by: (i) fusing a human kappa light chain constant domain (Ck) chain to the scFv to generate single chain antibody fragment (scAb) antibody fragments and (ii) by co-expression of the periplasmic chaperone Skp. While soluble, functional antibodies could be produced in this manner, phage-displaying scFvs or scAbs were still found to be superior ELISA reagents for immunoassays, due to the large signal amplification afforded by anti-phage antibodies. The isolated phage antibodies were shown to be highly specific to B. melitensis and did not recognize Yersinia pseudotuberculosis in contrast to the existing diagnostic monoclonal YST 9.2.1.

  13. Water-driven micromotors for rapid photocatalytic degradation of biological and chemical warfare agents.

    Science.gov (United States)

    Li, Jinxing; Singh, Virendra V; Sattayasamitsathit, Sirilak; Orozco, Jahir; Kaufmann, Kevin; Dong, Renfeng; Gao, Wei; Jurado-Sanchez, Beatriz; Fedorak, Yuri; Wang, Joseph

    2014-11-25

    Threats of chemical and biological warfare agents (CBWA) represent a serious global concern and require rapid and efficient neutralization methods. We present a highly effective micromotor strategy for photocatalytic degradation of CBWA based on light-activated TiO2/Au/Mg microspheres that propel autonomously in natural water and obviate the need for external fuel, decontaminating reagent, or mechanical agitation. The activated TiO2/Au/Mg micromotors generate highly reactive oxygen species responsible for the efficient destruction of the cell membranes of the anthrax simulant Bacillus globigii spore, as well as rapid and complete in situ mineralization of the highly persistent organophosphate nerve agents into nonharmful products. The water-driven propulsion of the TiO2/Au/Mg micromotors facilitates efficient fluid transport and dispersion of the photogenerated reactive oxidative species and their interaction with the CBWA. Coupling of the photocatalytic surface of the micromotors and their autonomous water-driven propulsion thus leads to a reagent-free operation which holds a considerable promise for diverse "green" defense and environmental applications.

  14. Biological and environmental hazards associated with exposure to chemical warfare agents: arsenicals.

    Science.gov (United States)

    Li, Changzhao; Srivastava, Ritesh K; Athar, Mohammad

    2016-08-01

    Arsenicals are highly reactive inorganic and organic derivatives of arsenic. These chemicals are very toxic and produce both acute and chronic tissue damage. On the basis of these observations, and considering the low cost and simple methods of their bulk syntheses, these agents were thought to be appropriate for chemical warfare. Among these, the best-known agent that was synthesized and weaponized during World War I (WWI) is Lewisite. Exposure to Lewisite causes painful inflammatory and blistering responses in the skin, lung, and eye. These chemicals also manifest systemic tissue injury following their cutaneous exposure. Although largely discontinued after WWI, stockpiles are still known to exist in the former Soviet Union, Germany, Italy, the United States, and Asia. Thus, access by terrorists or accidental exposure could be highly dangerous for humans and the environment. This review summarizes studies that describe the biological, pathophysiological, toxicological, and environmental effects of exposure to arsenicals, with a major focus on cutaneous injury. Studies related to the development of novel molecular pathobiology-based antidotes against these agents are also described. © 2016 New York Academy of Sciences.

  15. Biological and environmental hazards associated with exposure to chemical warfare agents: arsenicals

    Science.gov (United States)

    Li, Changzhao; Srivastava, Ritesh K.; Athar, Mohammad

    2016-01-01

    Arsenicals are highly reactive inorganic and organic derivatives of arsenic. These chemicals are very toxic and produce both acute and chronic tissue damage. Based on these observations, and considering the low cost and simple methods of their bulk syntheses, these agents were thought to be appropriate for chemical warfare. Among these, the most known agent synthesized and weaponized during World War I (WWI) is Lewisite. Exposure to Lewisite causes painful inflammatory and blistering responses in the skin, lung, and eye. These chemicals also manifest systemic tissue injury following their cutaneous exposure. Although largely discontinued after WWI, their stockpiles are still known to exist in the former Soviet Union, Germany, Italy, the United States, and Asia. Thus, their access by terrorists or accidental exposure could be highly dangerous for humans and the environment. This review summarizes studies which describe the biological, pathophysiological, toxicological, and environmental effects of exposure to arsenicals, with a major focus on cutaneous injury. Studies related to the development of novel molecular pathobiology–based antidotes against these agents are also described. PMID:27636894

  16. Radiation biology and radiation protection

    International Nuclear Information System (INIS)

    Hendry, J.H.

    2012-01-01

    For protection purposes, the biological effects of radiation are separated into stochastic effects (cancer, hereditary effects) presumed to be unicellular in origin, and tissue reactions due to injury in populations of cells. The latter are deterministic effects, renamed ‘tissue reactions’ in the 2007 Recommendations of the International Commission on Radiological Protection because of the increasing evidence of the ability to modify responses after irradiation. Tissue reactions become manifest either early or late after doses above a threshold dose, which is the basis for recommended dose limits for avoiding such effects. Latency time before manifestation is related to cell turnover rates, and tissue proliferative and structural organisation. Threshold doses have been defined for practical purposes at 1% incidence of an effect. In general, threshold doses are lower for longer follow-up times because of the slow progression of injury before manifestation. Radiosensitive individuals in the population may contribute to low threshold doses, and in the future, threshold doses may be increased by the use of various biological response modifiers post irradiation for reducing injury. Threshold doses would be expected to be higher for fractionated or protracted doses, unless doses below the threshold dose only cause single-hit-type events that are not modified by repair/recovery phenomena, or if different mechanisms of injury are involved at low and high doses.

  17. Biological Research for Radiation Protection

    International Nuclear Information System (INIS)

    Kim, In Gyu; Kim, Kug Chan; Jung, Il Lae; Choi, Yong Ho; Kim, Jin Sik; Moon, Myung Sook; Byun, Hee Sun; Phyo, Ki Heon; Kim, Sung Keun

    2005-04-01

    The work scope of 'Biological Research for the Radiation Protection' had contained the research about ornithine decarboxylase and its controlling proteins, thioredoxin, peroxiredoxin, S-adenosymethionine decarboxylase, and glutamate decarboxylase 67KD effect on the cell death triggered ionizing radiation and H 2 O 2 (toxic agents). In this study, to elucidate the role of these proteins in the ionizing radiation (or H 2 O 2 )-induced apoptotic cell death, we utilized sensesed (or antisensed) cells, which overexpress (or down-regulate) RNAs associated with these proteins biosynthesis, and investigated the effects of these genes on the cytotoxicity caused by ionizing radiation and H 2 O 2 (or paraquat). We also investigated whether genisteine(or thiamine) may enhance the cytotoxic efficacy of tumor cells caused by ionizing radiation (may enhance the preventing effect radiation or paraquat-induced damage) because such compounds are able to potentiate the cell-killing or cell protecting effects. Based on the above result, we suggest that the express regulation of theses genes have potentially importance for sensitizing the efficiency of radiation therapy of cancer or for protecting the radiation-induced damage of normal cells

  18. Biological research for radiation protection

    Energy Technology Data Exchange (ETDEWEB)

    Kim, In Gyu; Kim, Kug Chan; Shim, Hae Won; Oh, Tae Jeong; Park, Seon Young; Lee, Kang Suk

    2000-04-01

    The work scope of Biological research for the radiation protection had contained the search of biological microanalytic methods for assessing the health effect by {gamma}-radiation and toxic agents, the standardization of human T-lymphocyte cell culture and polymerase chain reaction, T-cell clonal assay, and the quantification of mutation frequency in the hypoxanthine (guanine) phosphoribosyl transferase (HPRT) gene locus by single exposure or combined exposure. Especially, the polymerase chain reaction methods using reverse transcriptase has been developed to analyze the mutant gene induced by {gamma}-radiation and chemical (pentachlorophenol) agent exposure, and to investigate the point mutations in the HPRT gene locus of T-lymphocytes. The HPRT T-cell clonal assay revealed that it could not differentiate {gamma}-irradiation from pentachlorophenol, because the frequency of somatic mutations induced by both damaging agents increased in a dose-dependent manner. The analysis of DNA sequence alterations of HPRT mutant clones clearly showed that both damaging agents induced different mutational spectra in the HPRT locus of T-cells. The large deletions, which account for 75 percent of the analyzed mutants, are characteristic mutations induced by {gamma}-irradiation. By contrast, point mutations such as base substitutions and insertion, come up to 97 percent in the case of pentachlorophenol-treated cells. The point mutation frequencies at 190 base pair and 444 base pair positions are 3-6 folds as high as in those at other mutation positions. It may be that these mutation sites are hot spots induced by pentachlorophenol. These results suggest that the HPRT mutation spectrum can be used as a potential bio marker for assessing a specific environmental risk. (author)

  19. Biological research for radiation protection

    International Nuclear Information System (INIS)

    Kim, In Gyu; Kim, Kug Chan; Shim, Hae Won; Oh, Tae Jeong; Park, Seon Young; Lee, Kang Suk

    2000-04-01

    The work scope of Biological research for the radiation protection had contained the search of biological microanalytic methods for assessing the health effect by γ-radiation and toxic agents, the standardization of human T-lymphocyte cell culture and polymerase chain reaction, T-cell clonal assay, and the quantification of mutation frequency in the hypoxanthine (guanine) phosphoribosyl transferase (HPRT) gene locus by single exposure or combined exposure. Especially, the polymerase chain reaction methods using reverse transcriptase has been developed to analyze the mutant gene induced by γ-radiation and chemical (pentachlorophenol) agent exposure, and to investigate the point mutations in the HPRT gene locus of T-lymphocytes. The HPRT T-cell clonal assay revealed that it could not differentiate γ-irradiation from pentachlorophenol, because the frequency of somatic mutations induced by both damaging agents increased in a dose-dependent manner. The analysis of DNA sequence alterations of HPRT mutant clones clearly showed that both damaging agents induced different mutational spectra in the HPRT locus of T-cells. The large deletions, which account for 75 percent of the analyzed mutants, are characteristic mutations induced by γ-irradiation. By contrast, point mutations such as base substitutions and insertion, come up to 97 percent in the case of pentachlorophenol-treated cells. The point mutation frequencies at 190 base pair and 444 base pair positions are 3-6 folds as high as in those at other mutation positions. It may be that these mutation sites are hot spots induced by pentachlorophenol. These results suggest that the HPRT mutation spectrum can be used as a potential bio marker for assessing a specific environmental risk. (author)

  20. Gulf war syndrome: could it be triggered by biological warfare-vaccines using pertussis as an adjuvant?

    Science.gov (United States)

    Tournier, J-N; Jouan, A; Mathieu, J; Drouet, E

    2002-04-01

    Several recent epidemiological studies have shown that vaccinations against biological warfare using pertussis as an adjuvant were associated with the Gulf war syndrome. If such epidemiological findings are confirmed, we propose that the use of pertussis as an adjuvant could trigger neurodegeneration through induction of interleukin-1beta secretion in the brain. In turn, neuronal lesions may be sustained by stress or neurotoxic chemical combinations. Particular susceptibility for IL-1beta secretion and potential distant neuronal damage could provide an explanation for the diversity of the symptoms observed on veterans. Copyright 2002 Elsevier Science Ltd. All rights reserved.

  1. Nuclear radiation in warfare

    International Nuclear Information System (INIS)

    Rotblat, J.

    1986-01-01

    The subject is covered in chapters, entitled: introduction; digest of nuclear weaponry (characteristics of nuclear weapons; effects of nuclear weapons other than ionizing radiation (fire-ball, fall-out, thermal radiation, blast wave, electromagnetic pulse); the nuclear arms race; war scenarios; biological effects of radiations on man (radiation doses; natural sources of radiation; acute effects of radiation; long-term somatic effects; genetic effects; factors affecting the biological response to radiation; internal exposure; synergistic effects; protection against radiation effects); radiations from nuclear explosions (initial radiation; fall-out; effects of fall-out on animal and plant life; contamination of water and food supplies by fall-out); radiation casualties in a nuclear war; effectiveness of civil defence; other warlike uses of radiation (attacks on civilian nuclear power installations; radiological warfare; terrorist activities); conclusion. (orig./HP) [de

  2. Nuclear radiation in warfare

    International Nuclear Information System (INIS)

    Rotblat, J.

    1981-01-01

    The subject is covered in chapters, entitled: introduction; digest of nuclear weaponry (characteristics of nuclear weapons; effects of nuclear weapons other than ionizing radiation (fire-ball, fall-out, thermal radiation, blast wave, electromagnetic pulse); the nuclear arms race; war scenarios); biological effects of radiations on man (radiation doses; natural sources of radiation; acute effects of radiation; long-term somatic effects; genetic effects; factors affecting the biological response to radiation; internal exposure; synergistic effects; protection against radiation effects); radiations from nuclear explosions (initial radiation; fall-out; effects of fall-out on animal and plant life; contamination of water and food supplies by fall-out); radiation casualties in a nuclear war; effectiveness of civil defence; other warlike uses of radiation (attacks on civilian nuclear power installations; radiological warfare; terrorist activities); conclusion. (U.K.)

  3. "Protected biological control"- Biological pest management in the greenhouse industry

    NARCIS (Netherlands)

    Pilkington, L.J.; Messelink, G.J.; Lenteren, van J.C.; Mottee, Le K.

    2010-01-01

    This paper briefly describes the foundations and characteristics of biological control in protected cropping and what drivers are behind adoption of this management system within this industry. Examining a brief history of biological control in greenhouses and what makes it a successful management

  4. Test Results of Level A Suits to Challenge by Chemical and Biological Warfare Agents and Simulants: Summary Report

    National Research Council Canada - National Science Library

    Belmonte, Richard B

    1998-01-01

    ...) terrorism incidents. As part of an effective response, people who are responding to an incident will use personal protective equipment to protect them from exposure to chemical agents or biological agents...

  5. Biological warfare warriors, secrecy and pure science in the Cold War: how to understand dialogue and the classifications of science.

    Science.gov (United States)

    Bud, Robert

    2014-01-01

    This paper uses a case study from the Cold War to reflect on the meaning at the time of the term 'Pure Science'. In 1961, four senior scientists from Britain's biological warfare centre at Porton Down visited Moscow both attending an International Congress and visiting Russian microbiological and biochemical laboratories. The reports of the British scientists in talking about a limited range of topics encountered in the Soviet Union expressed qualities of openness, sociologists of the time associated with pure science. The paper reflects on the discourses of "Pure Science", secrecy and security in the Cold War. Using Bakhtin's approach, I suggest the cordial communication between scientists from opposing sides can be seen in terms of the performance, or speaking, of one language among several at their disposal. Pure science was the language they were allowed to share outside their institutions, and indeed political blocs.

  6. Toxicity induced by chemical warfare agents: insights on the protective role of melatonin.

    Science.gov (United States)

    Pita, René; Marco-Contelles, José; Ramos, Eva; Del Pino, Javier; Romero, Alejandro

    2013-11-25

    Chemical Warfare Agents (CWAs) are substances that can be used to kill, injure or incapacitate an enemy in warfare, but also against civilian population in terrorist attacks. Many chemical agents are able to generate free radicals and derived reactants, excitotoxicity process, or inflammation, and as consequence they can cause neurological symptoms and damage in different organs. Nowadays, taking into account that total immediate decontamination after exposure is difficult to achieve and there are not completely effective antidotes and treatments against all CWAs, we advance and propose that medical countermeasures against CWAs poisoning would benefit from a broad-spectrum multipotent molecule. Melatonin, a versatile and ubiquitous antioxidant molecule, originally discovered as a hormone synthesized mainly in the pineal gland, has low toxicity and high efficacy in reducing oxidative damage, anti-inflammatory effects by regulation of multiple cellular pathways and properties to prevent excitotoxicity, among others. The purpose of this review is to show the multiple and diverse properties of melatonin, as a pleiotropic indole derivative, and its marked potential for improving human health against the most widely used chemical weapons. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  7. How Do I Know? A Guide to the Selection of Personal Protective Equipment for Use in Responding to A Release of Chemical Warfare Agents

    Energy Technology Data Exchange (ETDEWEB)

    Foust, C.B.

    1999-05-01

    An incident involving chemical warfare agents requires a unique hazardous materials (HAZMAT) response. As with an HAZMAT event, federal regulations prescribe that responders must be protected from exposure to the chemical agents. But unlike other HAZMAT events, special considerations govern selection of personal protective equipment (PPE). PPE includes all clothing, respirators and monitoring devices used to respond to a chemical release. PPE can differ depending on whether responders are military or civilian personnel.

  8. Evaluation of Chemical Warfare Agent Percutaneous Vapor Toxicity: Derivation of Toxicity Guidelines for Assessing Chemical Protective Ensembles.

    Energy Technology Data Exchange (ETDEWEB)

    Watson, A.P.

    2003-07-24

    Percutaneous vapor toxicity guidelines are provided for assessment and selection of chemical protective ensembles (CPEs) to be used by civilian and military first responders operating in a chemical warfare agent vapor environment. The agents evaluated include the G-series and VX nerve agents, the vesicant sulfur mustard (agent HD) and, to a lesser extent, the vesicant Lewisite (agent L). The focus of this evaluation is percutaneous vapor permeation of CPEs and the resulting skin absorption, as inhalation and ocular exposures are assumed to be largely eliminated through use of SCBA and full-face protective masks. Selection of appropriately protective CPE designs and materials incorporates a variety of test parameters to ensure operability, practicality, and adequacy. One aspect of adequacy assessment should be based on systems tests, which focus on effective protection of the most vulnerable body regions (e.g., the groin area), as identified in this analysis. The toxicity range of agent-specific cumulative exposures (Cts) derived in this analysis can be used as decision guidelines for CPE acceptance, in conjunction with weighting consideration towards more susceptible body regions. This toxicity range is bounded by the percutaneous vapor estimated minimal effect (EME{sub pv}) Ct (as the lower end) and the 1% population threshold effect (ECt{sub 01}) estimate. Assumptions of exposure duration used in CPE certification should consider that each agent-specific percutaneous vapor cumulative exposure Ct for a given endpoint is a constant for exposure durations between 30 min and 2 hours.

  9. Governing Warfare

    DEFF Research Database (Denmark)

    Harste, Gorm

      It would seem as though warfare has gotten out of control, not only in Iraq and Afghanistan, but also in Central Africa. The paper outlines the strategic history of politically controlled warfare since the early Enlightenment. The argument is that control is implausible. The idea of control has...

  10. Transport behavior of surrogate biological warfare agents in a simulated landfill: Effect of leachate recirculation and water infiltration

    KAUST Repository

    Saikaly, Pascal

    2010-11-15

    An understanding of the transport behavior of biological warfare (BW) agents in landfills is required to evaluate the suitability of landfills for the disposal of building decontamination residue (BDR) following a bioterrorist attack on a building. Surrogate BW agents, Bacillus atrophaeus spores and Serratia marcescens, were spiked into simulated landfill reactors that were filled with synthetic building debris (SBD) and operated for 4 months with leachate recirculation or water infiltration. Quantitative polymerase chain reaction (Q-PCR) was used to monitor surrogate transport. In the leachate recirculation reactors, <10% of spiked surrogates were eluted in leachate over 4 months. In contrast, 45% and 31% of spiked S. marcescens and B. atrophaeus spores were eluted in leachate in the water infiltration reactors. At the termination of the experiment, the number of retained cells and spores in SBD was measured over the depth of the reactor. Less than 3% of the total spiked S. marcescens cells and no B. atrophaeus spores were detected in SBD. These results suggest that significant fractions of the spiked surrogates were strongly attached to SBD. © 2010 American Chemical Society.

  11. Transport behavior of surrogate biological warfare agents in a simulated landfill: Effect of leachate recirculation and water infiltration

    KAUST Repository

    Saikaly, Pascal; Hicks, Kristin A.; Barlaz, Morton A.; De Los Reyes, Francis Delos De Los

    2010-01-01

    An understanding of the transport behavior of biological warfare (BW) agents in landfills is required to evaluate the suitability of landfills for the disposal of building decontamination residue (BDR) following a bioterrorist attack on a building. Surrogate BW agents, Bacillus atrophaeus spores and Serratia marcescens, were spiked into simulated landfill reactors that were filled with synthetic building debris (SBD) and operated for 4 months with leachate recirculation or water infiltration. Quantitative polymerase chain reaction (Q-PCR) was used to monitor surrogate transport. In the leachate recirculation reactors, <10% of spiked surrogates were eluted in leachate over 4 months. In contrast, 45% and 31% of spiked S. marcescens and B. atrophaeus spores were eluted in leachate in the water infiltration reactors. At the termination of the experiment, the number of retained cells and spores in SBD was measured over the depth of the reactor. Less than 3% of the total spiked S. marcescens cells and no B. atrophaeus spores were detected in SBD. These results suggest that significant fractions of the spiked surrogates were strongly attached to SBD. © 2010 American Chemical Society.

  12. Endemic infectious diseases and biological warfare during the Gulf War: a decade of analysis and final concerns.

    Science.gov (United States)

    Hyams, K C; Riddle, J; Trump, D H; Graham, J T

    2001-11-01

    Infectious diseases were one of the first health threats confronted by Coalition troops deployed to the Arabian desert in August 1990. On the basis of experiences in World War II, the major endemic infectious disease risks were thought to be sandfly fever, cutaneous leishmaniasis, diarrheal disease, and malaria. Although there was active surveillance, no case of sandfly fever and few other endemic infectious diseases were identified among over 500,000 U.S., British, and Canadian ground troops. In addition, there was no diagnosis of biological warfare (BW) exposure, and BW agents were not detected in clinical, environmental, or veterinary samples. The most common infectious disease problems were those associated with crowding (acute upper respiratory infections) and reduced levels of sanitation (travelers-type diarrhea). Only one endemic infectious disease has been confirmed as causing chronic health problems: visceral Leishmania tropica infection (viscerotropic leishmaniasis). However, this protozoan infection was diagnosed in only 12 U.S. veterans, and no new cases have been identified during the last 8 years. Infectious diseases were not a serious problem for Gulf War troops because of extensive preventive medicine efforts and favorable weather and geographic factors. Moreover, it is unlikely that an endemic infectious disease or a BW agent could cause chronic health problems and remain undetected over a 10-year period.

  13. Guerra biológica, bioterrorismo e saúde pública Biological warfare, bioterrorism and public health

    Directory of Open Access Journals (Sweden)

    Luiz Jacintho da Silva

    2001-12-01

    Full Text Available O uso de agentes biológicos como arma não é novidade para a humanidade. Durante séculos, até a atualidade, a guerra biológica tem sido objeto de muita pesquisa e especulação, mas de pouca ação. O medo de efeitos contrários e dúvidas sobre sua eficiência como armas devem ter limitado seu uso. Recentemente, se verificou uma nova forma de terrorismo, empregando agentes infecciosos, devagar e sem muito alarde, até as ocorrências recentes com o Bacillus anthracis nos Estados Unidos. A varíola é possivelmente o mais devastador desses agentes. Menos de 25 anos passados desde sua erradicação, a saúde pública tem que lidar com a possibilidade de sua re-introdução. O cenário da re-introdução da varíola no Brasil é discutido.Biological agents as weapons are not new to mankind. For centuries and into the present, biological warfare has been the subject of much research and speculation, but little action. Their limited use has probably been due to fear of unexpected counter-effects and doubts about their efficiency as weapons. Recently a new form of terrorism employing infectious agents has emerged slowly and without much fanfare, until the recent events with Bacillus anthracis in the United States. Smallpox is potentially the most devastating of these agents. Less than 25 years after the eradication of smallpox, the public health field is now forced to deal with the possibility of its re-introduction. The author discusses the scenario of smallpox re-introduction into Brazil.

  14. Effects of chemical and biological warfare remediation agents on the materials of museum objects

    Science.gov (United States)

    Solazzo, C.; Erhardt, D.; Marte, F.; von Endt, D.; Tumosa, C.

    In the fall of 2001, anthrax-contaminated letters were sent to public figures in the United States. Chemical and radiation treatments were employed to decontaminate exposed buildings, objects, and materials. These treatments are effective, but potentially damaging to exposed objects and materials. The recommended surface chemical treatments include solutions, gels, and foams of oxidizing agents such as peroxides or chlorine bleaching agents. Such oxidizing agents are effective against a wide range of hazardous chemical and biological agents. Knowing how these reagents affect various substrates would help to anticipate and to minimize any potential damage. We are examining the effects on typical museum materials of reagents likely to be used, including hydrogen peroxide, sodium hypochlorite, and potassium peroxymonosulfate. Results so far show significant changes in a number of materials. Surface corrosion was observed on metals such as copper, silver, iron, and brass. Color changes occurred with at least one reagent in about one-fourth of the dyed fabric swatches tested, and about half of the inks. Samples of aged yellowed paper are bleached. Effects varied with both the substrate and the tested reagent. The observed changes were generally less drastic than might have been expected. Enough materials were affected, though, to preclude the use of these reagents on museum objects unless no less drastic alternative is available. It appears that many objects of lesser intrinsic value can be treated without severe loss of properties or usefulness. For example, most documents should remain legible if the appropriate reagent is used. This work will provide a basis for determining which treatment is most appropriate for a specific situation and what consequences are to be expected from other treatments.

  15. Decontamination of chemical and biological warfare agents with a single multi-functional material.

    Science.gov (United States)

    Amitai, Gabi; Murata, Hironobu; Andersen, Jill D; Koepsel, Richard R; Russell, Alan J

    2010-05-01

    We report the synthesis of new polymers based on a dimethylacrylamide-methacrylate (DMAA-MA) co-polymer backbone that support both chemical and biological agent decontamination. Polyurethanes containing the redox enzymes glucose oxidase and horseradish peroxidase can convert halide ions into active halogens and exert striking bactericidal activity against gram positive and gram negative bacteria. New materials combining those biopolymers with a family of N-alkyl 4-pyridinium aldoxime (4-PAM) halide-acrylate co-polymers offer both nucleophilic activity for the detoxification of organophosphorus nerve agents and internal sources of halide ions for generation of biocidal activity. Generation of free bromine and iodine was observed in the combined material resulting in bactericidal activity of the enzymatically formed free halogens that caused complete kill of E. coli (>6 log units reduction) within 1 h at 37 degrees C. Detoxification of diisopropylfluorophosphate (DFP) by the polyDMAA MA-4-PAM iodide component was dose-dependent reaching 85% within 30 min. A subset of 4-PAM-halide co-polymers was designed to serve as a controlled release reservoir for N-hydroxyethyl 4-PAM (HE 4-PAM) molecules that reactivate nerve agent-inhibited acetylcholinesterase (AChE). Release rates for HE 4-PAM were consistent with hydrolysis of the HE 4-PAM from the polymer backbone. The HE 4-PAM that was released from the polymer reactivated DFP-inhibited AChE at a similar rate to the oxime antidote 4-PAM. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

  16. Biological research for the radiation protection

    International Nuclear Information System (INIS)

    Kim, In Gyu; Kim, Chan Kug; Shim, Hae Won; Jung, Il Lae; Byun, Hee Sun; Moon, Myung Sook; Cho, Hye Jeong; Kim, Jin Sik

    2003-04-01

    The work scope of 'Biological Research for the Radiation Protection' had contained the research about polyamine effect on cell death triggered ionizing radiation, H 2 O 2 and toxic agents. In this paper, to elucidate the role of polyamines as mediator in lysosomal damage and stress(H 2 O 2 )- induced apoptosis, we utilized α-DiFluoroMethylOrnithine (DFMO), which inhibited ornithine decarboxylase and depleted intracellular putrescine, and investigated the effects of polyamine on the apoptosis caused by H 2 O 2 , ionizing radiation and paraquat. We also showed that MGBG, inhibitor of polyamine biosynthesis, treatment affected intracellular redox steady states, intracellular ROS levels and protein oxidation. Thereafter we also investigated whether MGBG may enhance the cytotoxic efficacy of tumor cells caused by ionizing radiation or H 2 O 2 because such compounds are able to potentiate the cell-killing effects. In addition, ceruloplasmin and thioredoxin, possible antioxidant proteins, were shown to have protective effect on radiation- or H 2 O 2 (or chemicals)-induced macromolecular damage or cell death

  17. Accounting for biological effectiveness in radiological protection

    International Nuclear Information System (INIS)

    Dennis, J.A.

    1989-01-01

    Relative biological effectiveness (RBE) presents a practical problem to radiological protection when attempts are made to ensure that the assessed risks from different types of radiation and different modes of exposure to radiation are commensurate with one another. Unfortunately, the theoretical understanding of RBE is still in the stage of competing explanations and hypotheses. Furthermore, the division of the concept of dose equivalent into a set of concepts for risk assessment and another set for measurement and control has introduced conflicting requirements of a practical nature that are difficult to resolve. Many of those working in radiobiology and radiation protection have perceived the need to increase the quality factors for photon and neutron radiations. It may be more reasonable to change the quality factors for neutrons than for other radiations. The advantages and disadvantages of different methods for accommodating such changes within the dose-equivalent concepts are to be examined. The method of accommodating such a change that has the least practical disadvantages is to increase the quality factors for all secondary particles produced in tissue by neutron radiations by a constant factor. The only disadvantage would be the perception that the quality factors for these secondary particles were not treated in a consistent fashion for all types of ionising radiation. (author)

  18. Antifragile Electronic Warfare

    OpenAIRE

    Lichtman, Marc

    2014-01-01

    This letter introduces the concept of antifragile electronic warfare (EW), which we define as the ability to allow a communications link to improve performance due to the presence of a jammer. This concept should not be confused with jamming countermeasures (a.k.a. anti-jamming or electronic protection). Rather, antifragile EW can be thought of as the next step beyond simply avoiding or mitigating jamming. After introducing the concept we narrow down the subset of jammers this concept can be ...

  19. Biological and Chemical Warfare

    African Journals Online (AJOL)

    tar" making delivery into enemy lines surer and more accurate. ..... ceptible to antibiotic drugs, antibiotic-resist- ant strains occur ... means of a early warning system based on an automatic alarm ... given immediately by intramuscular injec- tion.

  20. [The re-introduction of malaria in the Pontine Marshes and the Cassino district during the end of World War II. Biological warfare or global war tactics?].

    Science.gov (United States)

    Sabbatani, Sergio; Fiorino, Sirio; Manfredi, Roberto

    2013-12-01

    After the fall of the Fascist regime on September 8, 1943, Italy was split into two parts: (i) the Southern regions where the King Victor Emanuel III and the military general staff escaped was under the control of English-American allied armies, and (ii) the northern regions comprising Lazio, Tuscany, Umbria, and Marche still under the control of the Germans. The German Wehrmacht, after suffering several defeats on Southern lines, established a new strengthened line of defence called the Gustav line, located south of Rome and crossing in the western portion the recently-drained Pontine Marshes. In his book published in 2006, Frank Snowden hypothesised that occupying German armies in 1943 had initiated a programme of re-flooding the Pontine plain as a biological warfare strategy to re-introduce malaria infection in the territories south of Rome, Such a plan was intended (i) to slow down the advance of English-American forces, and (ii) to punish Italians who abandoned their former allies. Other authors, including Annibale Folchi, Erhard Geissler, and Jeanne Guillemin, have disputed this hypothesis based on an analysis of recently-uncovered archive documents. What is not disputed is that the flooding of the Pontine and Roman plains in 1943 contributed to a severe malaria epidemic in 1944, which was associated with exceptionally high morbidity and mortality rates in the afflicted populations. Herein, we critically evaluate the evidence and arguments of whether the Wehrmacht specifically aimed to spread malaria as a novel biological warfare strategy in Italy during the Second World War. In our opinion, evidence for specific orders to deliberately spread malaria by the German army is lacking, although the strategy itself may have been considered by Nazis during the waning years of the war.

  1. Military Engineers and Chemical Warfare Troops (Inzhenernye Voiska Khimicheskie Voiska),

    Science.gov (United States)

    MILITARY FORCES(FOREIGN), *MILITARY ORGANIZATIONS, MILITARY ENGINEERING , INFANTRY, AMPHIBIOUS OPERATIONS, MINELAYING, ARMORED VEHICLES, NUCLEAR...RADIATION, DOSIMETERS, CHEMICAL WARFARE, PROTECTIVE CLOTHING, DECONTAMINATION, HEALTH PHYSICS.

  2. Radiation, chemical and biological protection. Mass destruction weapons

    International Nuclear Information System (INIS)

    Janasek, D.; Svetlik, J.

    2005-01-01

    In this text-book mass destruction weapons and radiation, chemical and biological protection are reviewed. The text-book contains the following chapter: (1) Mass destruction weapons; (2) Matter and material; (3) Radioactive materials; (4) Toxic materials; (5) Biological resources; (6) Nuclear energetic equipment; Appendices; References.

  3. Proceedings of the symposium on molecular biology and radiation protection

    Energy Technology Data Exchange (ETDEWEB)

    Marko, A M [Atomic Energy Control Board, Ottawa, ON (Canada). Advisory Committee on Radiological Protection; Myers, D K; Atchison, R J [Atomic Energy Control Board, Ottawa, ON (Canada). Advisory Committee on Radiological Protection. Secretariat; Gentner, N E [Atomic Energy of Canada Ltd., Chalk River, ON (Canada)

    1996-02-01

    The symposium on molecular biology and radiation protection was organized in sessions with the following titles: Radiation protection and the human genome; Molecular changes in DNA induced by radiation; Incidence of genetic changes - pre-existing, spontaneous and radiation-induced; Research directions and ethical implications. The ten papers in the symposium have been abstracted individually.

  4. Proceedings of the symposium on molecular biology and radiation protection

    International Nuclear Information System (INIS)

    Marko, A.M.

    1996-02-01

    The symposium on molecular biology and radiation protection was organized in sessions with the following titles: Radiation protection and the human genome; Molecular changes in DNA induced by radiation; Incidence of genetic changes - pre-existing, spontaneous and radiation-induced; Research directions and ethical implications. The ten papers in the symposium have been abstracted individually

  5. Cutaneous challenge with chemical warfare agents in the SKH-1 hairless mouse. (I) Development of a model for screening studies in skin decontamination and protection.

    Science.gov (United States)

    Dorandeu, F; Taysse, L; Boudry, I; Foquin, A; Hérodin, F; Mathieu, J; Daulon, S; Cruz, C; Lallement, G

    2011-06-01

    Exposure to lethal chemical warfare agents (CWAs) is no longer only a military issue due to the terrorist threat. Among the CWAs of concern are the organophosphorus nerve agent O-ethyl-S-(2[di-isopropylamino]ethyl)methyl-phosphonothioate (VX) and the vesicant sulfur mustard (SM). Although efficient means of decontamination are available, most of them lose their efficacy when decontamination is delayed after exposure of the bare skin. Alternatively, CWA skin penetration can be prevented by topical skin protectants. Active research in skin protection and decontamination is thus paramount. In vivo screening of decontaminants or skin protectants is usually time consuming and may be expensive depending on the animal species used. We were thus looking for a suitable, scientifically sound and cost-effective model, which is easy to handle. The euthymic hairless mouse Crl: SKH-1 (hr/hr) BR is widely used in some skin studies and has previously been described to be suitable for some experiments involving SM or SM analogs. To evaluate the response of this species, we studied the consequences of exposing male anaesthetized SKH-1 mice to either liquid VX or to SM, the latter being used in liquid form or as saturated vapours. Long-term effects of SM burn were also evaluated. The model was then used in the companion paper (Taysse et al.(1)).

  6. Wave basin model tests of technical-biological bank protection

    Science.gov (United States)

    Eisenmann, J.

    2012-04-01

    Sloped embankments of inland waterways are usually protected from erosion and other negative im-pacts of ship-induced hydraulic loads by technical revetments consisting of riprap. Concerning the dimensioning of such bank protection there are several design rules available, e.g. the "Principles for the Design of Bank and Bottom Protection for Inland Waterways" or the Code of Practice "Use of Standard Construction Methods for Bank and Bottom Protection on Waterways" issued by the BAW (Federal Waterways Engineering and Research Institute). Since the European Water Framework Directive has been put into action special emphasis was put on natural banks. Therefore the application of technical-biological bank protection is favoured. Currently design principles for technical-biological bank protection on inland waterways are missing. The existing experiences mainly refer to flowing waters with no or low ship-induced hydraulic loads on the banks. Since 2004 the Federal Waterways Engineering and Research Institute has been tracking the re-search and development project "Alternative Technical-Biological Bank Protection on Inland Water-ways" in company with the Federal Institute of Hydrology. The investigation to date includes the ex-amination of waterway sections where technical- biological bank protection is applied locally. For the development of design rules for technical-biological bank protection investigations shall be carried out in a next step, considering the mechanics and resilience of technical-biological bank protection with special attention to ship-induced hydraulic loads. The presentation gives a short introduction into hydraulic loads at inland waterways and their bank protection. More in detail model tests of a willow brush mattress as a technical-biological bank protec-tion in a wave basin are explained. Within the scope of these tests the brush mattresses were ex-posed to wave impacts to determine their resilience towards hydraulic loads. Since the

  7. Drone warfare

    Science.gov (United States)

    Gusterson, Hugh

    2017-11-01

    Crude drones existed as early as World War I, but the technology matured in the Yugoslav Wars of the 1990s and the current wars around the Middle East. The U.S. first used a weaponized drone in late 2001, in Afghanistan. Drones may cause more or less civilian casualties depending on the targeting protocols employed by their operators. There is an inherent ambiguity in determining who is an insurgent from several thousand feet, but civilian casualties are likely to be higher if targeters emphasize "signature strikes" over "personality strikes," if they engage in "double-tap strikes," if they rely too much on local informants, and if they rely too heavily on cellphone identification in the absence of corroboration from other intelligence sources. The legality of drone warfare is fairly clear in established battle zones such as Afghanistan, but is more problematic in terms of both international and domestic law when it comes to drone strikes in countries such as Yemen, Pakistan and Somalia with which the U.S. is not at war. Looking to the future, the U.S. would be well advised to sponsor negotiations for an international drone convention that might establish clear international rules for the use of drones, ban autonomous smart drones, and establish adjudicatory procedures to handle allegations of war crimes.

  8. 2006 Chemical Biological Individual Protection (CBIP) Conference and Exhibition

    Science.gov (United States)

    2006-03-09

    Requirements Office (JRO), MAJ W. Scott Smedley , Joint Requirements Office for Chemical, Biological, Radiological, and Nuclear Defense JPEO...Decker Director of Engineering 410-436-5600 www.ecbc.army.mil Gabe Patricio, JPEO 703 681-0808 Robert Wattenbarger, JPMOIP 703 432-3198 Canadian CBRN...UNCLASSIFIED Joint Requirements Office for Chemical, Biological, and Nuclear Defense MAJ W. Scott Smedley 8 March 2006 Individual Protection Conference

  9. A Medical Research and Evaluation Facility (MREF) and Studies Supporting the Medical Chemical Defense Program. Evaluation of the Passive Protection Against Five Serotypes of Botulinum Toxin Provided by Botulinum Human Immune Globulin in an Animal Model

    National Research Council Canada - National Science Library

    Olson, Carl

    1998-01-01

    Pentavalent (ABCDE) botulinum toxoid vaccine is intended for use as a prophylactic measure to protect combat troops against the lethal effects of botulinum toxins A-E, a group of toxins considered to be a serious biological warfare threat...

  10. HIGHLY SELECTIVE SENSORS FOR CHEMICAL AND BIOLOGICAL WARFARE AGENTS, INSECTICIDES AND VOCS BASED ON A MOLECULAR SURFACE IMPRINTING TECHNIQUE

    Science.gov (United States)

    Abstract was given as an oral platform presentation at the Pittsburgh Conference, Orlando FL (March 5-9, 2006). Research described is the development of sensors based on molecular surface imprinting. Applications include the monitoring of chemical and biological agents and inse...

  11. Flying Electronic Warfare Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Provides NP-3D aircraft host platforms for Effectiveness of Navy Electronic Warfare Systems (ENEWS) Program antiship missile (ASM) seeker simulators used...

  12. Information Warfare and Ethics

    Directory of Open Access Journals (Sweden)

    M.J. Warren

    2001-05-01

    Full Text Available This paper examines the ethics of the practice of information warfare at both the national and corporate levels. Initially examining the present and past actions of individual hackers, it moves to the more organised, future military and economic warfare scenarios. It examines the lack of legal or policy initiatives in this area.

  13. Difficult Decisions: Chemical Warfare.

    Science.gov (United States)

    Slesnick, Irwin L.; Miller, John A.

    1988-01-01

    Gives the background history and chemistry of modern day chemical warfare from World War I to the present. Provides discussion questions to stimulate deeper thinking on the issue. Contains a discussion activity called "Can New Chemical Weapons Lead to Humane Warfare?" (CW)

  14. Development of Quantitative Real-Time PCR Assays for Detection and Quantification of Surrogate Biological Warfare Agents in Building Debris and Leachate▿

    Science.gov (United States)

    Saikaly, Pascal E.; Barlaz, Morton A.; de los Reyes, Francis L.

    2007-01-01

    Evaluation of the fate and transport of biological warfare (BW) agents in landfills requires the development of specific and sensitive detection assays. The objective of the current study was to develop and validate SYBR green quantitative real-time PCR (Q-PCR) assays for the specific detection and quantification of surrogate BW agents in synthetic building debris (SBD) and leachate. Bacillus atrophaeus (vegetative cells and spores) and Serratia marcescens were used as surrogates for Bacillus anthracis (anthrax) and Yersinia pestis (plague), respectively. The targets for SYBR green Q-PCR assays were the 16S-23S rRNA intergenic transcribed spacer (ITS) region and recA gene for B. atrophaeus and the gyrB, wzm, and recA genes for S. marcescens. All assays showed high specificity when tested against 5 ng of closely related Bacillus and Serratia nontarget DNA from 21 organisms. Several spore lysis methods that include a combination of one or more of freeze-thaw cycles, chemical lysis, hot detergent treatment, bead beat homogenization, and sonication were evaluated. All methods tested showed similar threshold cycle values. The limit of detection of the developed Q-PCR assays was determined using DNA extracted from a pure bacterial culture and DNA extracted from sterile water, leachate, and SBD samples spiked with increasing quantities of surrogates. The limit of detection for B. atrophaeus genomic DNA using the ITS and B. atrophaeus recA Q-PCR assays was 7.5 fg per PCR. The limits of detection of S. marcescens genomic DNA using the gyrB, wzm, and S. marcescens recA Q-PCR assays were 7.5 fg, 75 fg, and 7.5 fg per PCR, respectively. Quantification of B. atrophaeus vegetative cells and spores was linear (R2 > 0.98) over a 7-log-unit dynamic range down to 101 B. atrophaeus cells or spores. Quantification of S. marcescens (R2 > 0.98) was linear over a 6-log-unit dynamic range down to 102 S. marcescens cells. The developed Q-PCR assays are highly specific and sensitive and can

  15. Continuing training program in radiation protection in biological research centers

    International Nuclear Information System (INIS)

    Escudero, R.; Hidalgo, R.M.; Usera, F.; Macias, M.T.; Mirpuri, E.; Perez, J.; Sanchez, A.

    2008-01-01

    The use of ionizing radiation in biological research has many specific characteristics. A great variety of radioisotopic techniques involve unsealed radioactive sources, and their use not only carries a risk of irradiation, but also a significant risk of contamination. Moreover, a high proportion of researchers are in training and the labor mobility rate is therefore high. Furthermore, most newly incorporated personnel have little or no previous training in radiological protection, since most academic qualifications do not include training in this discipline. In a biological research center, in addition to personnel whose work is directly associated with the radioactive facility (scientific-technical personnel, operators, supervisors), there are also groups of support personnel The use of ionizing radiation in biological research has many specific characteristics. A great variety of radioisotopic techniques involve unsealed radioactive sources, and their use not only carries a risk of irradiation, but also a significant risk of contamination. Moreover, a high proportion of researchers are in training and the labor mobility rate is therefore high. Furthermore, most newly incorporated personnel have little or no previous training in radiological protection, since most academic qualifications do not include training in this discipline. In a biological research center, in addition to personnel whose work is directly associated with the radioactive facility (scientific-technical personnel, operators, supervisors), there are also groups of support personnel maintenance and instrumentation workers, cleaners, administrative personnel, etc. who are associated with the radioactive facility indirectly. These workers are affected by the work in the radioactive facility to varying degrees, and they therefore also require information and training in radiological protection tailored to their level of interaction with the installation. The aim of this study was to design a

  16. Bragg Curve, Biological Bragg Curve and Biological Issues in Space Radiation Protection with Shielding

    Science.gov (United States)

    Honglu, Wu; Cucinotta, F.A.; Durante, M.; Lin, Z.; Rusek, A.

    2006-01-01

    The space environment consists of a varying field of radiation particles including high-energy ions, with spacecraft shielding material providing the major protection to astronauts from harmful exposure. Unlike low-LET gamma or X-rays, the presence of shielding does not always reduce the radiation risks for energetic charged particle exposure. Since the dose delivered by the charged particle increases sharply as the particle approaches the end of its range, a position known as the Bragg peak, the Bragg curve does not necessarily represent the biological damage along the particle traversal since biological effects are influenced by the track structure of both primary and secondary particles. Therefore, the biological Bragg curve is dependent on the energy and the type of the primary particle, and may vary for different biological endpoints. To achieve a Bragg curve distribution, we exposed cells to energetic heavy ions with the beam geometry parallel to a monolayer of fibroblasts. Qualitative analyses of gamma-H2AX fluorescence, a known marker of DSBs, indicated increased clustering of DNA damage before the Bragg peak, enhanced homogenous distribution at the peak, and provided visual evidence of high linear energy transfer (LET) particle traversal of cells beyond the Bragg peak. A quantitative biological response curve generated for micronuclei (MN) induction across the Bragg curve did not reveal an increased yield of MN at the location of the Bragg peak. However, the ratio of mono-to bi-nucleated cells, which indicates inhibition in cell progression, increased at the Bragg peak location. These results, along with other biological concerns, show that space radiation protection with shielding can be a complicated issue.

  17. Measuring management success for protected species: Looking beyond biological outcomes

    Directory of Open Access Journals (Sweden)

    Kathryn D Bisack

    2016-05-01

    Full Text Available The complexity of the ocean ecosystem, including the human component, is such that a single fishery may require multiple policy instruments to support recovery and conservation of protected species, in addition to those for fisheries management. As regulations multiply, the need for retrospective analysis and evaluation grows in order to inform future policy. To accurately evaluate policy instruments, clear objectives and their link to outcomes are necessary, as well as identifying criteria to evaluate outcomes. The Northeast United States sink gillnet groundfish fishery provides a case study of the complexity of regulations and policy instruments implemented under the Marine Mammal Protection Act and the Endangered Species Act to address bycatch of marine mammals. The case study illustrates a range of possible objectives for the policy instruments including biological, economic, social-normative and longevity factors. We highlight links between possible objectives, outcomes and criteria for the four factors, as well as areas for consideration when undertaking ex-post analyses. To support learning from past actions, we call for a coordinated effort involving multiple disciplines and jurisdictions to undertake retrospective analyses and evaluations of key groups of policy instruments used for protected species.

  18. Defining cyber warfare

    Directory of Open Access Journals (Sweden)

    Dragan D. Mladenović

    2012-04-01

    Full Text Available Cyber conflicts represent a new kind of warfare that is technologically developing very rapidly. Such development results in more frequent and more intensive cyber attacks undertaken by states against adversary targets, with a wide range of diverse operations, from information operations to physical destruction of targets. Nevertheless, cyber warfare is waged through the application of the same means, techniques and methods as those used in cyber criminal, terrorism and intelligence activities. Moreover, it has a very specific nature that enables states to covertly initiate attacks against their adversaries. The starting point in defining doctrines, procedures and standards in the area of cyber warfare is determining its true nature. In this paper, a contribution to this effort was made through the analysis of the existing state doctrines and international practice in the area of cyber warfare towards the determination of its nationally acceptable definition.

  19. Chemical, Biological, Radiological, Nuclear, and High-Yield Explosives Consequences Management

    Science.gov (United States)

    2006-10-02

    protective measures associated with such offensive operations. Since riot control agents and herbicides are not considered to be chemical warfare agents...control. Procedures to avoid, reduce, remove, or render harmless (temporarily or permanently) nuclear, radiological, biological, and chemical...destroying, neutralizing, making harmless , or removing chemical or biological agents, or by removing radioactive material clinging to or around it. (JP 1

  20. Protecting innovation in bioinformatics and in-silico biology.

    Science.gov (United States)

    Harrison, Robert

    2003-01-01

    Commercial success or failure of innovation in bioinformatics and in-silico biology requires the appropriate use of legal tools for protecting and exploiting intellectual property. These tools include patents, copyrights, trademarks, design rights, and limiting information in the form of 'trade secrets'. Potentially patentable components of bioinformatics programmes include lines of code, algorithms, data content, data structure and user interfaces. In both the US and the European Union, copyright protection is granted for software as a literary work, and most other major industrial countries have adopted similar rules. Nonetheless, the grant of software patents remains controversial and is being challenged in some countries. Current debate extends to aspects such as whether patents can claim not only the apparatus and methods but also the data signals and/or products, such as a CD-ROM, on which the programme is stored. The patentability of substances discovered using in-silico methods is a separate debate that is unlikely to be resolved in the near future.

  1. Cyber Warfare/Cyber Terrorism

    National Research Council Canada - National Science Library

    O'Hara, Timothy

    2004-01-01

    Section 1 of this paper provides an overview of cyber warfare as an element of information warfare, starting with the general background of the current strategic environment the United States is operating...

  2. Chemical warfare agents.

    Science.gov (United States)

    Kuca, Kamil; Pohanka, Miroslav

    2010-01-01

    Chemical warfare agents are compounds of different chemical structures. Simple molecules such as chlorine as well as complex structures such as ricin belong to this group. Nerve agents, vesicants, incapacitating agents, blood agents, lung-damaging agents, riot-control agents and several toxins are among chemical warfare agents. Although the use of these compounds is strictly prohibited, the possible misuse by terrorist groups is a reality nowadays. Owing to this fact, knowledge of the basic properties of these substances is of a high importance. This chapter briefly introduces the separate groups of chemical warfare agents together with their members and the potential therapy that should be applied in case someone is intoxicated by these agents.

  3. Chemical warfare agents. Classes and targets.

    Science.gov (United States)

    Schwenk, Michael

    2018-09-01

    Synthetic toxic chemicals (toxicants) and biological poisons (toxins) have been developed as chemical warfare agents in the last century. At the time of their initial consideration as chemical weapon, only restricted knowledge existed about their mechanisms of action. There exist two different types of acute toxic action: nonspecific cytotoxic mechanisms with multiple chemo-biological interactions versus specific mechanisms that tend to have just a single or a few target biomolecules. TRPV1- and TRPA-receptors are often involved as chemosensors that induce neurogenic inflammation. The present work briefly surveys classes and toxicologically relevant features of chemical warfare agents and describes mechanisms of toxic action. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. The Physics of Warfare

    Science.gov (United States)

    Giordano, Gerardo

    2015-01-01

    Recently, I was tasked with the creation and execution of a new themed general education physics class called The Physics of Warfare. In the past, I had used the theme of a class, such as the physics of sports medicine, as a way to create homework and in-class activities, generate discussions, and provide an application to demonstrate that physics…

  5. The Impacts of Modern Warfare on Freshwater Ecosystems

    Science.gov (United States)

    Francis, Robert A.

    2011-11-01

    There is increasing recognition and concern regarding the impacts of modern industrial warfare on the environment. Freshwater ecosystems are perhaps the most vulnerable to warfare-related impacts, which is of concern given that they provide so many essential environmental resources and services to society. Despite this, there has been little work to establish and quantify the types of impacts (both negative and positive) that warfare may have on such systems. This paper firstly highlights why rivers and lakes may be susceptible to warfare-related impacts, before synthesizing the available literature to explore the following main themes: intensification of wartime resource acquisition, use of water as an offensive or defensive weapon, direct and indirect effects of explosive ordnance, increased pollution, introduction of invasive alien species, and positive ecological impacts. This is then followed by a discussion of the implications of such impacts in relation to future warfare, including a consideration of the efficacy of existing legal instruments to protect the environment during conflict, and the trend for war to become more localized and `informal', and therefore less regulated. Finally, the paper identifies key research foci for understanding and mitigating the effects of warfare on freshwater ecosystems.

  6. Information Warfare and International Law

    National Research Council Canada - National Science Library

    Greenberg, Lawrence T; Goodman, Seymour E; Soo Hoo, Kevin J

    1998-01-01

    .... Some legal constraints will certainly apply to information warfare, either because the constraints explicitly regulate particular actions, or because more general principles of international law...

  7. Electronic Warfare Signature Measurement Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Electronic Warfare Signature Measurement Facility contains specialized mobile spectral, radiometric, and imaging measurement systems to characterize ultraviolet,...

  8. Implications of Network Centric Warfare

    National Research Council Canada - National Science Library

    Bailey, Alvin

    2004-01-01

    .... These areas of dependence also provide numerous vulnerabilities. This paper will focus specifically on Network Centric Warfare's vulnerabilities in terms of sensors cyberterrorism/ Electro-Magnetic Pulse (EMP...

  9. Biological bases for radiation protection standards and implications for policy

    International Nuclear Information System (INIS)

    Beninson, D.

    1987-01-01

    The author sums up the principles involved in radiation as being composed of three basic requirements: 1) the individual dose limitation 2) the justification of radiation sources or practices 3) the optimization of protection. This philosophy is more sophisticated than the old approach of threshold and safety factors, which, however, is still valid for protection against non-stochastic effects. Discussion following presentation of the paper ranged over cost benefit analysis and optimization of protection systems, uranium mining, and the varying reactions of different governments. (U.K.)

  10. Biological Criteria for Protection of U.S. Coral Reefs.

    Science.gov (United States)

    Coral reef ecosystems are threatened by natural stressors, human activities, and natural stressors exacerbated by human activities. Under the U.S. Clean Water Act, States and Territories may guard against anthropogenic threats by adopting water quality standards based on biologic...

  11. Psychological effects of nuclear warfare

    International Nuclear Information System (INIS)

    Mickley, G.A.

    1987-01-01

    This report is divided into five parts. (1) Discussion of the psychological milieu before a nuclear confrontation. (2) Acute psychological reactions to nuclear warfare (some of which may reflect, in part, direct radiogenic alteration of nervous system functions). (3) Chronic psychological effects of a nuclear confrontation. (4) Issues concerning treatment of these psychological changes. (5) Prevention of adverse psychological reactions to nuclear warfare

  12. Biologically Hazardous Agents at Work and Efforts to Protect Workers' Health: A Review of Recent Reports

    Directory of Open Access Journals (Sweden)

    Kyung-Taek Rim

    2014-06-01

    Full Text Available Because information on biological agents in the workplace is lacking, biological hazard analyses at the workplace to securely recognize the harmful factors with biological basis are desperately needed. This review concentrates on literatures published after 2010 that attempted to detect biological hazards to humans, especially workers, and the efforts to protect them against these factors. It is important to improve the current understanding of the health hazards caused by biological factors at the workplace. In addition, this review briefly describes these factors and provides some examples of their adverse health effects. It also reviews risk assessments, protection with personal protective equipment, prevention with training of workers, regulations, as well as vaccinations.

  13. Radiation protection in biological investigation centers. Problematic, development and perspectives

    International Nuclear Information System (INIS)

    Macias, M.T.; Pina, R.; Usera, F.

    1998-01-01

    The radiological risk derivatives from the radioisotope techniques accomplished in the different investigation lines developed in the Centers object of this work, have necessary made establishing an organization that assure some adequate protection conditions in the use of the ionizing radiations

  14. Radiologic science for technologists: physics, biology, and protection

    International Nuclear Information System (INIS)

    Bushong, S.C.

    1980-01-01

    The second edition of a textbook primarily for students in radiologic technology is presented. Separate chapters discuss mammography, computed tomography, diagnostic ultrasound, and design of radiologic physics. Radiation protection is specifically presented in two chapters as well as being integrated throughout the text. The fundamentals of radiobiology, molecular and cellular effects of irradiation, and early and late radiation effects comprise four chapters

  15. Radiation protection standards: a summary of the biological effects of ionising radiation and principles of radiation protection

    International Nuclear Information System (INIS)

    1994-01-01

    This leaflet in the NRPB At-a-Glance-Series briefly summarises the biological effects of radiation, harm and sensitivity to radiation, radiation protection principles, acceptability of risk and the control of doses to workers, the public and in medical procedures in the UK. (UK)

  16. Cyber warfare and electronic warfare integration in the operational environment of the future: cyber electronic warfare

    Science.gov (United States)

    Askin, Osman; Irmak, Riza; Avsever, Mustafa

    2015-05-01

    For the states with advanced technology, effective use of electronic warfare and cyber warfare will be the main determining factor of winning a war in the future's operational environment. The developed states will be able to finalize the struggles they have entered with a minimum of human casualties and minimum cost thanks to high-tech. Considering the increasing number of world economic problems, the development of human rights and humanitarian law it is easy to understand the importance of minimum cost and minimum loss of human. In this paper, cyber warfare and electronic warfare concepts are examined in conjunction with the historical development and the relationship between them is explained. Finally, assessments were carried out about the use of cyber electronic warfare in the coming years.

  17. Effective protection of biological membranes against photo-oxidative damage: Polymeric antioxidant forming a protecting shield over the membrane.

    Science.gov (United States)

    Mertins, Omar; Mathews, Patrick D; Gomide, Andreza B; Baptista, Mauricio S; Itri, Rosangela

    2015-10-01

    We have prepared a chitosan polymer modified with gallic acid in order to develop an efficient protection strategy biological membranes against photodamage. Lipid bilayers were challenged with photoinduced damage by photosensitization with methylene blue, which usually causes formation of hydroperoxides, increasing area per lipid, and afterwards allowing leakage of internal materials. The damage was delayed by a solution of gallic acid in a concentration dependent manner, but further suppressed by the polymer at very low concentrations. The membrane of giant unilamellar vesicles was covered with this modified macromolecule leading to a powerful shield against singlet oxygen and thus effectively protecting the lipid membrane from oxidative stress. The results have proven the discovery of a promising strategy for photo protection of biological membranes. Copyright © 2015 Elsevier B.V. All rights reserved.

  18. Hybrid Maritime Warfare

    DEFF Research Database (Denmark)

    Schaub Jr, Gary John; Murphy, Martin; Hoffman, Frank

    2017-01-01

    Russia’s use of hybrid warfare techniques has raised concerns about the security of the Baltic States. Gary Schaub, Jr, Martin Murphy and Frank G Hoffman recommend a series of measures to augment NATO’s Readiness Action Plan in the Baltic region, including increasing the breadth and depth of naval...... exercises, and improving maritime domain awareness through cooperative programmes. They also suggest unilateral and cooperative measures to develop a sound strategic communications strategy to counter Moscow’s information operations, reduce dependence on Russian energy supplies and build the resilience...

  19. Electronic Warfare: Towed Decoys Could Improve Survivability of Current Navy Aircraft

    National Research Council Canada - National Science Library

    Aiken, Michael

    1997-01-01

    Traditionally, DOD'S combat aircraft have used on-board electronic warfare devices called jammers for self-protection against radar-controlled weapons, including missiles and anti-aircraft artillery...

  20. MEDICAL PROTECTION FOR THE EXPEDITIONARY FORCE IN THE EVENT OF USING BIOLOGICAL AGENTS

    Directory of Open Access Journals (Sweden)

    Viorel ORDEANUL

    2014-12-01

    Full Text Available The ADM/CBRN military or terrorist attack is most likely to be enforced on the force deployed in the theaters of operations (TO, as peace making troops, peace keeping troops, etc. For the medical protection of the expeditionary forces deployed in external theaters of operations (T.O., when using biological agents, we conducted a documentary study on the prophylaxis and specific treatment for the medical force protection, when using biological agents, by updating and improving the medical protection countermeasures against BWA, by anti-infective prophylaxis (antibacterial and antiviral pre-exposure, post-exposure and anti-infective etiology and support of the vital fuctions treatment.

  1. New methodologies of biological dosimetry applied to human protection

    International Nuclear Information System (INIS)

    Catena, C.; Parasacchi, P.; Conti, D.; Righi, E.

    1995-04-01

    Biological dosimetry is a diagnostic methodology for the measurement of the individual dose absorbed in the case of accidental overexposition to ionizing radiation. It is demonstrated how in vitro radiobiological and chemobiological studies using cytogenetic methods (count of chromosomal aberrations and micronuclei) on human lymphocytes from healthy subjects and individuals undergoing radiotherapy or chemotherapy, as well as on lymphocytes of mammals other than man (comparative cytogenetics), can help to increase the basic radiobiological and chemobiological scientific information. Such information gives a valid contribution to understanding of the action of ionizing radiation or of pharmaceuticals on cells and, in return, can be of value to human radioprotection and chemoprotection. Cytogenetic studies can be summerized as follows: a) biodosimetry (estimate of dose received after accidental events); b) individual radiosensitivity (level of individual response); c) clinical radiobiology and chemobiology (individual response to radiopharmaceuticals, to radiotherapy and to chemopharmaceuticals); d) comparative radiobiology (cytogenetic studies on species other than man); e) animal model in the environmental surveillance

  2. Establishing Cyber Warfare Doctrine

    Directory of Open Access Journals (Sweden)

    Andrew M. Colarik

    2012-01-01

    Full Text Available Over the past several decades, advances in technology have transformed communications and the ability to acquire, disseminate, and utilize information in a range of environments. Modern societies and their respective militaries have taken advantage of a robust information space through network-centric systems. Because military and commercial operations have increasingly converged, communication and information infrastructures are now high-priority military objectives in times of war. This article examines the theoretical underpinning of current cyber warfare research, what we have learned so far about its application, and some of the emerging themes to be considered; it also postulates the development of a (national cyber warfare doctrine (CWD. An endeavor of this scale requires lots of considerations and preparation for its development if it is to be cooperatively embraced. This article considers why information technology systems and their supporting infrastructures should be considered legitimate military targets in conflicts, and offers several events that support this supposition. In addition, it identifies the various forms of doctrine that will become the basis for developing a CWD, discusses a CWD's possible components, and proposes a national collaborative and discussion framework for obtaining a nation's stakeholder buy-in for such an endeavor.

  3. Nondestructive inspection of chemical warfare based on API-TOF

    International Nuclear Information System (INIS)

    Wang Xinhua; Zheng Pu; He Tie; An Li; Yang Jie; Fan Yu

    2013-01-01

    Background: Real-time, fast, accurate, nondestructive inspection (NDI) and quantitative analysis for chemical warfare are very imperative for chemical defense, anti-terror and nation security. Purpose: Associated Particles Technique (APT)/Neutron Time of Flight (TOF) has been developed for non-invasive inspection of sealed containers with chemical warfare agents. Methods: A prototype equipment for chemical warfare is consisted of an APT neutron generator with a 3×3 matrix of semiconductor detectors of associated alpha-particles, the shielding protection of neutron and gamma-ray, arrayed NaI(Tl)-based detectors of gamma-rays, fully-digital data acquisition electronics, data analysis, decision-making software, support platform and remote control system. Inelastic scattering gamma-ray pulse height spectra of sarin, VX, mustard gas and adamsite induced by 14-MeV neutron are measured. The energies of these gamma rays are used to identify the inelastic scattering elements, and the intensities of the peaks at these energies are used to reveal their concentrations. Results: The characteristic peaks of inelastic scattering gamma-ray pulse height spectra show that the prototype equipment can fast and accurately inspect chemical warfare. Conclusion: The equipment can be used to detect not only chemical warfare agents but also other hazardous materials, such as chemical/toxic/drug materials, if their chemical composition is in any way different from that of the surrounding materials. (authors)

  4. Nuclear radiation in warfare. A SIPRI publication. Strahlungswirkungen beim Einsatz von Kernwaffen. Eine SIPRI-Publikation

    Energy Technology Data Exchange (ETDEWEB)

    Rotblat, J.

    1986-01-01

    The subject is covered in chapters, entitled: introduction; digest of nuclear weaponry (characteristics of nuclear weapons; effects of nuclear weapons other than ionizing radiation (fire-ball, fall-out, thermal radiation, blast wave, electromagnetic pulse); the nuclear arms race; war scenarios; biological effects of radiations on man (radiation doses; natural sources of radiation; acute effects of radiation; long-term somatic effects; genetic effects; factors affecting the biological response to radiation; internal exposure; synergistic effects; protection against radiation effects); radiations from nuclear explosions (initial radiation; fall-out; effects of fall-out on animal and plant life; contamination of water and food supplies by fall-out); radiation casualties in a nuclear war; effectiveness of civil defence; other warlike uses of radiation (attacks on civilian nuclear power installations; radiological warfare; terrorist activities); conclusion.

  5. Biological activity of Penaeus monodon GILT in shrimp pathogen protection

    Directory of Open Access Journals (Sweden)

    Aekkaraj Nualla-ong

    2017-04-01

    Full Text Available Gamma-interferon-inducible lysosomal thiol reductase (GILT contains a CXXC active site motif that possesses thiol reductase activity by catalyzing the disulfide bond reduction of exogenous antigens. Mutating the active site of human GILT to change the cysteine residues to serine residues eliminates this property. Our previous study reported that Penaeus monodon GILT (PmGILT contained a CXXS active site motif. Therefore, we assessed the enzymatic activity of PmGILT and demonstrated that it displayed identical thiol reductase activity at an acidic pH. In addition, the biological activity of PmGILT against shrimp pathogens, including white spot syndrome virus (WSSV and Gram-negative bacteria, was investigated. The neutralization of WSSV with PmGILT indicated the inhibition of WSSV invasion into shrimp hemocyte cells. Moreover, the relative percentage survival of shrimp injected with PmGILT-treated virus solution was 75%. Finally, the antimicrobial activity of PmGILT was confirmed by the growth inhibition of Vibrio harveyi. These results establish the role of PmGILT in the inhibition of the virulence of two major shrimp pathogens.

  6. [Vectors of malaria: biology, diversity, prevention, and individual protection].

    Science.gov (United States)

    Pages, F; Orlandi-Pradines, E; Corbel, V

    2007-03-01

    Only the Anopheles mosquitoes are implicated in the transmission of malaria. Among the numerous species of anopheles, around fifty are currently involved in the transmission. 20 are responsible for most of the transmission in the world. The diversity of behavior between species and in a single species of anopheles as well as climatic and geographical conditions along with the action of man on the environment condition the man vector contact level and the various epidemiological aspects of malaria. The anopheles are primarily rural mosquitoes and are less likely to be found in city surroundings in theory. But actually, the adaptation of some species to urban surroundings and the common habit of market gardening in big cities or in the suburbs is responsible for the de persistence of Anopheles populations in town. Except for South-East Asia, urban malaria has become a reality. The transmission risk of malaria is heterogeneous and varies with time. There is a great variation of risk within a same country, a same zone, and even within a few kilometers. The transmission varies in time according to seasons but also according to years and to the level of climatic events. For the traveler, prevention at any time relies on the strict application of individual protection, as well in rural than in urban surroundings.

  7. Cyber Warfare/Cyber Terrorism

    National Research Council Canada - National Science Library

    O'Hara, Timothy

    2004-01-01

    .... Section 1 concludes with a review of offensive and defensive cyber warfare concepts. Section 2 presents a general overview of cyber terrorism, including definitions of cyber terrorism and cyber terrorism support...

  8. Attrition in Network Centric Warfare

    National Research Council Canada - National Science Library

    Erbetta, John

    2003-01-01

    .... Information warfare means that positive attacks on systems themselves compound the problem. Emerging technologies applicable to NCW as a force multiplier need to be recognized as counter to the impediments to progress...

  9. The ethics of information warfare

    CERN Document Server

    Floridi, Luciano

    2014-01-01

    This book offers an overview of the ethical problems posed by Information Warfare, and of the different approaches and methods used to solve them, in order to provide the reader with a better grasp of the ethical conundrums posed by this new form of warfare.The volume is divided into three parts, each comprising four chapters. The first part focuses on issues pertaining to the concept of Information Warfare and the clarifications that need to be made in order to address its ethical implications. The second part collects contributions focusing on Just War Theory and its application to the case of Information Warfare. The third part adopts alternative approaches to Just War Theory for analysing the ethical implications of this phenomenon. Finally, an afterword by Neelie Kroes - Vice President of the European Commission and European Digital Agenda Commissioner - concludes the volume. Her contribution describes the interests and commitments of the European Digital Agenda with respect to research for the developme...

  10. Warfare, genocide, and ethnic conflict: a Darwinian approach

    OpenAIRE

    Dimijian, Gregory G.

    2010-01-01

    As the 21st century dawns, I reflect on the history of humankind with growing concern about the need to understand the underlying biological and cultural roots of ethnic conflict and warfare. In the many studies of human conflict, innate biological predispositions have been neglected. This article is the third part of a series of seminars for medical residents at the University of Texas Southwestern Medical School at Dallas (see http://adarwinstudygroup.org/). The series starts with in-depth ...

  11. Reflections on nuclear warfare

    International Nuclear Information System (INIS)

    Evans, J.P.

    1983-01-01

    The author looks back on his more than 70 years of familiarity with Americans involved in warfare, noting their loyal support for our country's objectives. Drawing on the Einstein equation, his own visits to Hiroshima and Nagasaki, and current literature, he, as a physician, belatedly concurs with those who look on the use of nuclear weapons as irrational and untenable. Their employment under present circumstances would create a ''final epidemic'' to be avoided only by prevention. He suggests that medical perceptions must be considered by our national leaders in assessing the many factors that he hopes will lead to rational answers to this urgent, highly complex, and vital enigma. He cites physicians' efforts to help in finding answers and asks that his colleagues consider the issues with attention to the gravity of the situation and act according to their best judgment

  12. Intelligence Strategy for Fourth Generation Warfare

    National Research Council Canada - National Science Library

    Jamison, Edward P

    2006-01-01

    ...." They have named this new era of war "fourth generation warfare." Currently the Department of Defense's intelligence strategy is designed to defeat conventional adversaries vise a fourth generation warfare opponent...

  13. CORAL REEF BIOLOGICAL CRITERIA: USING THE CLEAN WATER ACT TO PROTECT A NATIONAL TREASURE

    Science.gov (United States)

    Coral reefs are declining at unprecedented rates worldwide due to multiple interactive stressors including climate change and land-based sources of pollution. The Clean Water Act (CWA) can be a powerful legal instrument for protecting water resources, including the biological inh...

  14. Integration of biological control and transgenic insect protection for mitigation of mycotoxins in corn

    Science.gov (United States)

    Biological control is known to be effective in reducing aflatoxin contamination of corn and some transgenic corn hybrids incur greatly reduced damage from corn earworm (Helicoverpa zea). We conducted seven field trials over two years to test the hypothesis that transgenic insect protection and biol...

  15. Warfare in biodiversity hotspots.

    Science.gov (United States)

    Hanson, Thor; Brooks, Thomas M; Da Fonseca, Gustavo A B; Hoffmann, Michael; Lamoreux, John F; Machlis, Gary; Mittermeier, Cristina G; Mittermeier, Russell A; Pilgrim, John D

    2009-06-01

    Conservation efforts are only as sustainable as the social and political context within which they take place. The weakening or collapse of sociopolitical frameworks during wartime can lead to habitat destruction and the erosion of conservation policies, but in some cases, may also confer ecological benefits through altered settlement patterns and reduced resource exploitation. Over 90% of the major armed conflicts between 1950 and 2000 occurred within countries containing biodiversity hotspots, and more than 80% took place directly within hotspot areas. Less than one-third of the 34 recognized hotspots escaped significant conflict during this period, and most suffered repeated episodes of violence. This pattern was remarkably consistent over these 5 decades. Evidence from the war-torn Eastern Afromontane hotspot suggests that biodiversity conservation is improved when international nongovernmental organizations support local protected area staff and remain engaged throughout the conflict. With biodiversity hotspots concentrated in politically volatile regions, the conservation community must maintain continuous involvement during periods of war, and biodiversity conservation should be incorporated into military, reconstruction, and humanitarian programs in the world's conflict zones. ©2009 Society for Conservation Biology.

  16. Physical, chemical, and biological properties of radiocerium relevant to radiation protection guidelines

    International Nuclear Information System (INIS)

    Anon.

    1978-01-01

    Present knowledge of the relevant physical, chemical, and biological properties of radiocerium as a basis for establishing radiation protection guidelines is summarized. The first section of the report reviews the chemical and physical properties of radiocerium relative to the biological behavior of internally-deposited cerium and other lanthanides. The second section of the report gives the sources of radiocerium in the environment and the pathways to man. The third section of the report describes the metabolic fate of cerium in several mammalian species as a basis for predicting its metabolic fate in man. The fourth section of the report considers the biomedical effects of radiocerium in light of extensive animal experimentation. The last two sections of the report describe the history of radiation protection guidelines for radiocerium and summarize data required for evaluating the adequacy of current radiation protection guidelines. Each section begins with a summary of the most important findings that follow

  17. Development of an Active Topical Skin Protectant (aTSP)

    Science.gov (United States)

    2016-02-01

    protectant as a follow-on product to Skin Exposure Reduction Paste Against Chemical Warfare Agents (SERPACWA). 15. SUBJECT TERMS decontamination , Skin...corresponding author), Chemical Warfare Agent Decontamination from Skin, In J.A. Romano Jr., B.J. Lukey, and H. Salem, eds., 2nd Edition of Chemical Warfare ...CG, and Braue, EH Jr (corresponding author), “ Chemical warfare agent decontamination from skin,” In J.A. Romano Jr., B.J. Lukey, and H. Salem

  18. A Hypothesis on Biological Protection from Space Radiation Through the Use of New Therapeutic Gases

    Science.gov (United States)

    Schoenfeld, Michael P.; Ansari, Rafat R.; Nakao, Atsunori; Wink, David

    2011-01-01

    Radiation exposure to astronauts could be a significant obstacle for long duration manned space exploration because of current uncertainties regarding the extent of biological effects. Furthermore, concepts for protective shielding also pose a technically challenging issue due to the nature of cosmic radiation and current mass and power constraints with modern exploration technology. The concern regarding exposure to cosmic radiation is the biological damage it induces. As damage is associated with increased oxidative stress, it is important and would be enabling to mitigate and/or prevent oxidative stress prior to the development of clinical symptoms and disease. This paper hypothesizes a "systems biology" approach in which a combination of chemical and biological mitigation techniques are used conjunctively. It proposes using new, therapeutic, medical gases as both chemical radioprotectors for radical scavenging and biological signaling molecules for management of the body s response to exposure. From reviewing radiochemistry of water, biological effects of CO, H2, NO, and H2S gas, and mechanisms of radiation biology, it is concluded that this approach may have great therapeutic potential for radiation exposure. Furthermore, it also appears to have similar potential for curtailing the pathogenesis of other diseases in which oxidative stress has been implicated including cardiovascular disease, cancer, chronic inflammatory disease, hypertension, ischemia/reperfusion injury, acute respiratory distress syndrome, Parkinson s and Alzheimer s disease, cataracts, and aging.

  19. The ethics of drone warfare

    Directory of Open Access Journals (Sweden)

    Fatić Aleksandar

    2017-01-01

    Full Text Available The paper investigates the compatibility of the modern technologies of warfare, specifically the use of offensive drones, with traditional military ethics and suggests that the new technologies radically change the value system of the military in ways which make large parts of the traditional military ethics inapplicable. The author suggests that Agamben’s concept of ‘effectivity’ through ‘special actions’ which mark one’s belonging to a particular community or profession is a useful conceptual strategy to explore the compatibility of drone warfare with traditional military ethics; this strategy shows mixed results at best.

  20. The doctor and nuclear warfare

    International Nuclear Information System (INIS)

    Anon.

    1982-01-01

    At the 34th World Medical Assembly in Lisbon in 1981 the World Medical Association adopted a motion proposed by the American Medical Association that national medical associations should develop programs to educate the civilian population on the medical consequences of nuclear war. This article discusses the attitude the medical professions should have, should nuclear warfare in some form confront them in the future. The conclusion is drawn that defence against nuclear warfare is only a part of civil defence against any disaster, including the natural disasters such as flood and fire and the man-made disasters of transport accidents, even of problems at nuclear plants designed to supply energy

  1. Simulating cyber warfare and cyber defenses: information value considerations

    Science.gov (United States)

    Stytz, Martin R.; Banks, Sheila B.

    2011-06-01

    Simulating cyber warfare is critical to the preparation of decision-makers for the challenges posed by cyber attacks. Simulation is the only means we have to prepare decision-makers for the inevitable cyber attacks upon the information they will need for decision-making and to develop cyber warfare strategies and tactics. Currently, there is no theory regarding the strategies that should be used to achieve objectives in offensive or defensive cyber warfare, and cyber warfare occurs too rarely to use real-world experience to develop effective strategies. To simulate cyber warfare by affecting the information used for decision-making, we modify the information content of the rings that are compromised during in a decision-making context. The number of rings affected and value of the information that is altered (i.e., the closeness of the ring to the center) is determined by the expertise of the decision-maker and the learning outcome(s) for the simulation exercise. We determine which information rings are compromised using the probability that the simulated cyber defenses that protect each ring can be compromised. These probabilities are based upon prior cyber attack activity in the simulation exercise as well as similar real-world cyber attacks. To determine which information in a compromised "ring" to alter, the simulation environment maintains a record of the cyber attacks that have succeeded in the simulation environment as well as the decision-making context. These two pieces of information are used to compute an estimate of the likelihood that the cyber attack can alter, destroy, or falsify each piece of information in a compromised ring. The unpredictability of information alteration in our approach adds greater realism to the cyber event. This paper suggests a new technique that can be used for cyber warfare simulation, the ring approach for modeling context-dependent information value, and our means for considering information value when assigning cyber

  2. Tissue-based standoff biosensors for detecting chemical warfare agents

    Science.gov (United States)

    Greenbaum, Elias; Sanders, Charlene A.

    2003-11-18

    A tissue-based, deployable, standoff air quality sensor for detecting the presence of at least one chemical or biological warfare agent, includes: a cell containing entrapped photosynthetic tissue, the cell adapted for analyzing photosynthetic activity of the entrapped photosynthetic tissue; means for introducing an air sample into the cell and contacting the air sample with the entrapped photosynthetic tissue; a fluorometer in operable relationship with the cell for measuring photosynthetic activity of the entrapped photosynthetic tissue; and transmitting means for transmitting analytical data generated by the fluorometer relating to the presence of at least one chemical or biological warfare agent in the air sample, the sensor adapted for deployment into a selected area.

  3. Laboratory Aspects of Biological Warfare Agents

    Science.gov (United States)

    2016-01-01

    Brucella IgM and IgA bound to milk fat globules in cow or goat milk . False positives may occur with this test in colostrum, milk at the end of a lactation...is typically via aerosolization of infectious particles, by ingesting contaminated raw milk and cheese, and by tick vectors. The infectious dose is...such as amplification of the infectious agent’s nucleic acids or an immunoassay targeted toward the infectious agent’s proteins . Direct

  4. Information Management and the Biological Warfare Threat

    National Research Council Canada - National Science Library

    Martinez, Antonio

    2002-01-01

    ...: the scientific paradigm, the business paradigm and the security paradigm. The findings of this thesis demonstrate an information sharing paradigm favoring full and open access to scientific data currently being practiced by the U.S...

  5. Conflict Without Casualties: Non-Lethal Weapons in Irregular Warfare

    Science.gov (United States)

    2007-09-01

    the body,” and the Geneva Protocol of 1925, bans the use of chemical and biological weapons .11 On 8 April 1975, President Ford issued Executive...E Funding – PE 63851M) (accessed 15 December 2006). The American Journal of Bioethics . “Medical Ethics and Non-Lethal Weapons .” Bioethics.net...CASUALTIES: NON-LETHAL WEAPONS IN IRREGULAR WARFARE by Richard L. Scott September 2007 Thesis Advisor: Robert McNab Second Reader

  6. Ionizing radiation biological effects and the proper protective measures against it's harmful effects

    International Nuclear Information System (INIS)

    Hhalel, A.M.

    1990-01-01

    This book intrduces a good knowledge in specifications of ionizing radiation biological effects and the proper protective measures againest harmful effectes. The book is devided in to five main sections, the first one introduces the hostorical bachground of the contributions of a number of scietists in the basic knolwledge of radiation and its biological effects. The second section deals with the physical and chemical principles of radiation the third one talks about radiation detection. While the fourth section talks (via seven chapter) about the effectes of ionizing radiation on living organisms molecules cells, tissues organs systems and the living organism the fifth section talks about the uses of radiation sources, the probability of radiation accidents, protective measures, international recommendations related to doses and safe use of ionizing radiation. (Abed Al-wali Al-ajlouni). 53 refs., 107 figs., 13 tabs

  7. Biological oxygen demand in soils and hydrogel compositions for plant protection of the rhizosphere

    Science.gov (United States)

    Valentinovich Smagin, Andrey

    2018-02-01

    Potential biological activity of mineral and organogenic samples from light-textured sod-podzolic soils as well as of hydrogel compositions for protecting the root layer from pathogenic microflora and unfavorable edaphic factors were studied in laboratory conditions by oxygen consumption under the optimal hydrothermic conditions with portable gas analyzers. We have conducted ecological standardization of biological activity and organic matter destruction estimated by biological oxygen demand (BOD) in the widespread sandy soils. The primary outcome was the scale of gradations of biological oxygen uptake in soils with a range of quantities of potential biological activity from “very low” (140 g·m-3·hour-1), obtained on the basis of statistical processing of data array 1308 measurements. Acrylic polymer hydrogels had BOD = 0.2-2 g·m-3·hour-1, which corresponded to the periods of their half-lives from 0.2±0.1 to 6.8± 4.5 years, or relatively low resistance to biodestruction. In contrast to the pure gels, hydrogel compositions for rhizosphere based on ionic and colloidal silver showed low biological activity (BOD=0.01-0.2 g·m-3· hour-1) and, accordingly, significant resistance to biodegradation with half-lives from 5 to 70 years and above.

  8. European Curricula, Xenophobia and Warfare.

    Science.gov (United States)

    Coulby, David

    1997-01-01

    Examines school and university curricula in Europe and the extent of their influence on xenophobia. Considers the pluralistic nature of the European population. Discusses the role of curriculum selection and language policy in state efforts to promote nationalism. Assesses the role of curricular systems in the actual encouragement of warfare,…

  9. The Anatomy of Counterinsurgency Warfare

    DEFF Research Database (Denmark)

    Mouritsen, Lars; Pedersen, Kenneth; Thruelsen, Peter Dahl

    Since the beginning of the new millennium, the West has been increasingly involved in a tiresome and rather particular type of conflict: insurgency warfare. The bloody and shocking terrorist attacks on New York and Washington in September 2001 marked the beginning of a new era, and the introducti...

  10. Strategic Analysis of Irregular Warfare

    Science.gov (United States)

    2010-03-01

    the same mathematical equations used by Lanchester .10 Irregular Warfare Theory and Doctrine It is time to develop new analytical methods and models...basis on which to build, similar to what Lanchester provided almost 100 years ago. Figure 9 portrays both Lanchester’s approach and an irregular 17

  11. Roots of Russian Irregular Warfare

    Science.gov (United States)

    2016-12-01

    PAGE INTENTIONALLY LEFT BLANK xiii ACKNOWLEDGMENTS Crissy, your encouragement throughout my career and especially during this project has been...all of the Russian disinformation techniques in Ukraine came directly “from Soviet toolkits .” Maria Snegovaya, “Putin’s Information Warfare In

  12. Technology Transition for Hybrid Warfare

    Science.gov (United States)

    2010-02-16

    and Iraq. At the same time, the science and technology base must provide the disruptive technologies to defeat future conventional enemies. This... disruptive technologies will be needed to retain long-term technological superiority in conventional warfare. Incremental improvement is the most...technology to be missed. Disruptive technologies are the second type of technological change and involve revolutionary concepts involving large technological

  13. Expanding Kenya's protected areas under the Convention on Biological Diversity to maximize coverage of plant diversity.

    Science.gov (United States)

    Scherer, Laura; Curran, Michael; Alvarez, Miguel

    2017-04-01

    Biodiversity is highly valuable and critically threatened by anthropogenic degradation of the natural environment. In response, governments have pledged enhanced protected-area coverage, which requires scarce biological data to identify conservation priorities. To assist this effort, we mapped conservation priorities in Kenya based on maximizing alpha (species richness) and beta diversity (species turnover) of plant communities while minimizing economic costs. We used plant-cover percentages from vegetation surveys of over 2000 plots to build separate models for each type of diversity. Opportunity and management costs were based on literature data and interviews with conservation organizations. Species richness was predicted to be highest in a belt from Lake Turkana through Mount Kenya and in a belt parallel to the coast, and species turnover was predicted to be highest in western Kenya and along the coast. Our results suggest the expanding reserve network should focus on the coast and northeastern provinces of Kenya, where new biological surveys would also fill biological data gaps. Meeting the Convention on Biological Diversity target of 17% terrestrial coverage by 2020 would increase representation of Kenya's plant communities by 75%. However, this would require about 50 times more funds than Kenya has received thus far from the Global Environment Facility. © 2016 Society for Conservation Biology.

  14. Unconventional Cyber Warfare: Cyber Opportunities in Unconventional Warfare

    Science.gov (United States)

    2014-06-01

    Internet service provider IW irregular warfare MCO major combat operations MySQL open-source relational database management system NATO North...today, often with no regard for legal or ethical constraints. A better course of action would be to conduct operations in cyberspace within the precepts...built in feature of MySQL that 97 John Markoff, “Before the Gunfire, Cyberattacks,” York Times, August 13, 2008, sec. Technology, 1, http

  15. Hybrid Warfare: the 21st Century Russian Way of Warfare

    Science.gov (United States)

    2017-05-25

    to wage information operations— from television, to the Internet, to unconventional forces on the ground spreading the message word -of- mouth ...adversarial vulnerabilities. Many of the peculiarities of hybrid warfare described herein are inextricably linked to Russia’s social , political, and...the US election. Then they utilized various means of media to distribute that information with the goal to discredit the US political process and

  16. Biological Control to Protect Watermelon Blossoms and Seed from Infection by Acidovorax avenae subsp. citrulli.

    Science.gov (United States)

    Fessehaie, A; Walcott, R R

    2005-04-01

    ABSTRACT The efficacy of biological control seed treatments with Pseudomonas fluorescens (A506), Acidovorax avenae subsp. avenae (AAA 99-2), and an unidentified gram-positive bacterium recovered from watermelon seed (WS-1) was evaluated for the management of bacterial fruit blotch (BFB) of watermelon. In growth chamber and greenhouse experiments, seed treated with AAA 99-2 displayed superior disease suppression, reducing BFB transmission by 96.5%. AAA 99-2, P. fluorescens A506, and Kocide also suppressed the epiphytic growth of A. avenae subsp. citrulli when applied to attached watermelon blossoms 5 h prior to inoculation. Watermelon blossom protection reduced seed infestation by A. avenae subsp. citrulli. From blossoms treated with 0.1 M phosphate buffered saline (PBS), 63% of the resulting seed lots were infested with A. avenae subsp. citrulli. In contrast, for blossoms protected with WS-1, Kocide, P. fluorescens A506, and AAA 99-2, the proportion of infested seed lots were 48.3, 21.1, 24.1, and 13.8%, respectively. The effect of blossom treatments on seed lot infestation was statistically significant (P = 0.001) but WS-1 was not significantly different from PBS. These findings suggest that blossom protection with biological control agents could be a feasible option for managing BFB.

  17. Future development of biological understanding of radiation protection: implications of nonstochastic effects

    International Nuclear Information System (INIS)

    Hahn, F.F.; McClellan, R.O.; Boecker, B.B.; Muggenburg, B.A.

    1988-01-01

    Radiation-protection standards are based on minimizing or preventing biological effects in exposed populations. Radiation-induced biological effects can be classified as stochastic--malignant and hereditary diseases for which the probability of an effect occurring is a function of dose without threshold--and nonstochastic--inflammatory and degenerative diseases for which the severity and frequency of the effect varies with the dose and for which a threshold is present. The current International Commission on Radiation Protection (ICRP) approach for setting limits for intakes of radionuclides by workers, which accounts for doses to significantly exposed organs of the body, is based on limitation of stochastic effects in most situations. When setting exposure limits, nonstochastic effects are generally considered to be unlikely at the limits for stochastic effects. In some situations, limits based on prevention of nonstochastic effects are lower than for stochastic effects. This review considers the threshold radiation doses for thyroid, bone, liver and lung and their relationship to the limits recommended by the ICRP and the cancer risks at the limits. This review indicates that the threshold dose for nonstochastic effects in thyroid and lung is much above the dose limit as advocated by ICRP. The threshold dose for nonstochastic effects in bone and liver is much closer to the dose limit, but protection from nonstochastic effects should still be afforded by the dose limits

  18. 2008 13th Expeditionary Warfare Conference

    Science.gov (United States)

    2008-10-23

    platforms – Emphasize a mixed fleet approach that spans the “iron triangle” – Integrate MRAP into the fleet mix – Transition to a fleet of tactical...Urban Warfare Mountain Warfare Desert Warfare Jungle Riverine Special Skills Recon LOG CSS ENG MT HS Ord Maint EOD Pers Retrival ...Detection (Specialized Platform FLGPR)Stand-off (60M) Scaleable Neutralization (Area coverage) ABV Delivery Ground Cueing Stand-off (800M) Scaleable

  19. Military medicine and the ethics of war: British colonial warfare during the Seven Years War (1756-63).

    Science.gov (United States)

    Charters, Erica

    2010-01-01

    This article examines 18th-century European warfare, tracing the first formal codifications of conventions of war, frequently introduced by military physicians and initially regarding the treatment of the sick and wounded. It outlines to what extent these conventions were followed in practice, particularly in the challenging environment of American irregular warfare, with a focus on the most well-known incident of "biological warfare" in the period: the deliberate spread of smallpox by British officers among Amerindians in 1763. More broadly, it demonstrates that the history of military medicine provides a fruitful method with which to uncover assumptions about the ethics of war.

  20. Tissue-based water quality biosensors for detecting chemical warfare agents

    Science.gov (United States)

    Greenbaum, Elias [Oak Ridge, TN; Sanders, Charlene A [Knoxville, TN

    2003-05-27

    A water quality sensor for detecting the presence of at least one chemical or biological warfare agent includes: a cell; apparatus for introducing water into the cell and discharging water from the cell adapted for analyzing photosynthetic activity of naturally occurring, free-living, indigenous photosynthetic organisms in water; a fluorometer for measuring photosynthetic activity of naturally occurring, free-living, indigenous photosynthetic organisms drawn into the cell; and an electronics package that analyzes raw data from the fluorometer and emits a signal indicating the presence of at least one chemical or biological warfare agent in the water.

  1. Information Warfare in the Cyber Domain

    National Research Council Canada - National Science Library

    Takemoto, Glenn

    2001-01-01

    ...). This paper lays a foundation by defining the terminology associated with Information Warfare in the Cyber Domain, reviews the threat and illustrates the vulnerabilities of our information systems...

  2. MEANS AND METHODS OF CYBER WARFARE

    Directory of Open Access Journals (Sweden)

    Dan-Iulian VOITAȘEC

    2016-06-01

    Full Text Available According to the Declaration of Saint Petersburg of 1868 “the only legitimate object which States should endeavor to accomplish during war is to weaken the military forces of the enemy”. Thus, International Humanitarian Law prohibits or limits the use of certain means and methods of warfare. The rapid development of technology has led to the emergence of a new dimension of warfare. The cyber aspect of armed conflict has led to the development of new means and methods of warfare. The purpose of this paper is to study how the norms of international humanitarian law apply to the means and methods of cyber warfare.

  3. Cyber warfare building the scientific foundation

    CERN Document Server

    Jajodia, Sushil; Subrahmanian, VS; Swarup, Vipin; Wang, Cliff

    2015-01-01

    This book features a wide spectrum of the latest computer science research relating to cyber warfare, including military and policy dimensions. It is the first book to explore the scientific foundation of cyber warfare and features research from the areas of artificial intelligence, game theory, programming languages, graph theory and more. The high-level approach and emphasis on scientific rigor provides insights on ways to improve cyber warfare defense worldwide. Cyber Warfare: Building the Scientific Foundation targets researchers and practitioners working in cyber security, especially gove

  4. Shadow Wars: An Analysis of Counterinsurgency Warfare

    National Research Council Canada - National Science Library

    Dogan, Osman

    2005-01-01

    ... of the current strategic approaches to counterinsurgency warfare. Toward this end, a systems model approach, which views insurgent organizations as open systems, is adapted to the insurgent environment...

  5. Toward a biologically significant and usable standard for ozone that will also protect plants

    International Nuclear Information System (INIS)

    Paoletti, Elena; Manning, William J.

    2007-01-01

    Ozone remains an important phytotoxic air pollutant and is also recognized as a significant greenhouse gas. In North America, Europe, and Asia, incidence of high concentrations is decreasing, but background levels are steadily rising. There is a need to develop a biologically significant and usable standard for ozone. We compare the strengths and weaknesses of concentration-based, exposure-based and threshold-based indices, such as SUM60 and AOT40, and examine the O 3 flux concept. We also present major challenges to the development of an air quality standard for ozone that has both biological significance and practicality in usage. - Current standards do not protect vegetation from ozone, but progress is being made

  6. Methodological issues in analyzing time trends in biologic fertility: protection bias

    DEFF Research Database (Denmark)

    Key, Jane; Best, Nicky; Joffe, Michael

    2009-01-01

    One method of assessing biologic fertility is to measure time to pregnancy (TTP). Accidental pregnancies do not generate a valid TTP value and lead to nonrandom missing data if couples experiencing accidental pregnancies are more fertile than the general population. If factors affecting the rate...... of fertility trends in Europe over the past 50 years. Couples experiencing accidental pregnancies tended to be more fertile than the general population. However, trends in accidental pregnancy rates were inconsistent across countries and were insufficient to produce substantial bias in fertility trends...... of accidental pregnancies, such as availability of effective contraception and induced abortion, vary over time, then the result may be protection bias in the estimates of fertility time trends. Six European data sets were analyzed to investigate whether evidence of protection bias exists in TTP studies...

  7. The ethics of drone warfare

    OpenAIRE

    Fatić Aleksandar

    2017-01-01

    The paper investigates the compatibility of the modern technologies of warfare, specifically the use of offensive drones, with traditional military ethics and suggests that the new technologies radically change the value system of the military in ways which make large parts of the traditional military ethics inapplicable. The author suggests that Agamben’s concept of ‘effectivity’ through ‘special actions’ which mark one’s belonging to a particular communit...

  8. Radioecological aspects of nuclear warfare

    International Nuclear Information System (INIS)

    Edvardson, Kay

    1977-01-01

    Radioactive fallout, one of the major effects of nuclear warfare, will cause acute radiation sickness within the close-in or intermediate areas downwind from surface bursts. Global fallout from high yield explosions will be fairly evenly distributed in the hemisphere where the explosions occur, and will cause irradiation from ground deposit, inhaled material and contaminated food. Estimates of collective doses and the approximate number of late casualties from the global contamination are presented for a given total explosion yield. (author)

  9. Hybrid Warfare: Preparing for Future Conflict

    Science.gov (United States)

    2015-02-17

    ciceromagazine.com/?s=getting+behind+hybrid+warfare. Brown , Col Leslie F. “Twenty-First Century Warfare Will be Hybrid.” Carlisle Barracks, PA...Lebanon and Gaza.” Rand Corporation Occasional Paper. Santa Monica, CA: Rand Corporation, 2010. Jones, Gareth and Darya Korsunskaya. “U.S., EU

  10. Reactivity of Dual-Use Decontaminants with Chemical Warfare Agents

    Science.gov (United States)

    2016-07-01

    REACTIVITY OF DUAL-USE DECONTAMINANTS WITH CHEMICAL WARFARE AGENTS ECBC-TR-1384... Decontaminants with Chemical Warfare Agents 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Willis, Matthew P...extraction) of chemical warfare agents from materials. 15. SUBJECT TERMS GD HD Decontamination Hazard mitigation VX Chemical warfare agent Liquid-phase

  11. The Information Warfare Life Cycle Model

    Directory of Open Access Journals (Sweden)

    Brett van Niekerk

    2011-11-01

    Full Text Available Information warfare (IW is a dynamic and developing concept, which constitutes a number of disciplines. This paper aims to develop a life cycle model for information warfare that is applicable to all of the constituent disciplines. The model aims to be scalable and applicable to civilian and military incidents where information warfare tactics are employed. Existing information warfare models are discussed, and a new model is developed from the common aspects of these existing models. The proposed model is then applied to a variety of incidents to test its applicability and scalability. The proposed model is shown to be applicable to multiple disciplines of information warfare and is scalable, thus meeting the objectives of the model.

  12. The Information Warfare Life Cycle Model

    Directory of Open Access Journals (Sweden)

    Brett van Niekerk

    2011-03-01

    Full Text Available Information warfare (IW is a dynamic and developing concept, which constitutes a number of disciplines. This paper aims to develop a life cycle model for information warfare that is applicable to all of the constituent disciplines. The model aims to be scalable and applicable to civilian and military incidents where information warfare tactics are employed. Existing information warfare models are discussed, and a new model is developed from the common aspects of these existing models. The proposed model is then applied to a variety of incidents to test its applicability and scalability. The proposed model is shown to be applicable to multiple disciplines of information warfare and is scalable, thus meeting the objectives of the model.

  13. Ethylene glycol monolayer protected nanoparticles: synthesis, characterization, and interactions with biological molecules.

    Science.gov (United States)

    Zheng, Ming; Li, Zhigang; Huang, Xueying

    2004-05-11

    The usefulness of the hybrid materials of nanoparticles and biological molecules on many occasions depends on how well one can achieve a rational design based on specific binding and programmable assembly. Nonspecific binding between nanoparticles and biomolecules is one of the major barriers for achieving their utilities in a biological system. In this paper, we demonstrate a new approach to eliminate nonspecific interactions between nanoparticles and biological molecules by shielding the nanoparticle with a monolayer of ethylene glycol. A direct synthesis of di-, tri-, and tetra(ethylene glycol)-protected gold nanoparticles (Au-S-EGn, n = 2, 3, and 4) was achieved under the condition that the water content was optimized in the range of 9-18% in the reaction mixture. With controlled ratio of [HAuCl4]/[EGn-SH] at 2, the synthesized particles have an average diameter of 3.5 nm and a surface plasma resonance band around 510 nm. Their surface structures were confirmed by 1H NMR spectra. These gold nanoparticles are bonded with a uniform monolayer with defined lengths of 0.8, 1.2, and 1.6 nm for Au-S-EG2, Au-S-EG3, and Au-S-EG4, respectively. They have great stabilities in aqueous solutions with a high concentration of electrolytes as well as in organic solvents. Thermogravimetric analysis revealed that the ethylene glycol monolayer coating is ca. 14% of the total nanoparticle weight. Biological binding tests by using ion-exchange chromatography and gel electrophoresis demonstrated that these Au-S-EGn (n = 2, 3, or 4) nanoparticles are free of any nonspecific bindings with various proteins, DNA, and RNA. These types of nanoparticles provide a fundamental starting material for designing hybrid materials composed of metallic nanoparticles and biomolecules.

  14. Radioecological aspects of nuclear warfare

    International Nuclear Information System (INIS)

    Edvarson, K.

    1975-01-01

    The radioactive fallout from nuclear explosions is one of the major effects of nuclear warfare. Those levels causing acute radiation sickness are to be expected only within the close-in or intermediate areas downwind from surface bursts. Global fallout from high yield explosions will be fairly evenly distributed in the hemisphere where the explosions occurred and cause irradiation from ground deposit, inhaled material and contaminated food. The collective doses and the order of magnitude of late casualties from this global contamination are estimated for a given total explosion yield. (auth)

  15. Laboratory analysis of chemical warfare agents, adducts, and metabolites in biomedial samples

    NARCIS (Netherlands)

    Schans, M.J. van der

    2015-01-01

    Chemical warfare agents (CWAs) are the most toxic compounds ever produced. To develop medical countermeasures against the effects of these agents, analytical procedures to analyze these agents in biological matrices are essential for a better understanding of the toxicological process. The need for

  16. Diagnosis of exposure to chemical warfare agents: An essential tool to counteract chemical terrorism

    NARCIS (Netherlands)

    Noort, D.; Schans, M.J. van der; Bikker, F.J.; Benschop, H.P.

    2009-01-01

    Methods to analyze chemical warfare agents (CW-agents) and their decomposition products in environmental samples were developed over the last decades. In contrast herewith, procedures for analysis in biological samples have only recently been developed. Retrospective detection of exposure to

  17. Biologically-Inspired Concepts for Autonomic Self-Protection in Multiagent Systems

    Science.gov (United States)

    Sterritt, Roy; Hinchey, Mike

    2006-01-01

    Biologically-inspired autonomous and autonomic systems (AAS) are essentially concerned with creating self-directed and self-managing systems based on metaphors &om nature and the human body, such as the autonomic nervous system. Agent technologies have been identified as a key enabler for engineering autonomy and autonomicity in systems, both in terms of retrofitting into legacy systems and in designing new systems. Handing over responsibility to systems themselves raises concerns for humans with regard to safety and security. This paper reports on the continued investigation into a strand of research on how to engineer self-protection mechanisms into systems to assist in encouraging confidence regarding security when utilizing autonomy and autonomicity. This includes utilizing the apoptosis and quiescence metaphors to potentially provide a self-destruct or self-sleep signal between autonomic agents when needed, and an ALice signal to facilitate self-identification and self-certification between anonymous autonomous agents and systems.

  18. Biological effects and radiation protection in veterinary radiology: a literature review

    International Nuclear Information System (INIS)

    Rosa, P.C.; Siqueira, D.; Barros, F.S.

    2017-01-01

    Veterinary radiology is a tool of excellent diagnostic support. Besides X--ray, it counts on technological advances such as computed tomography, nuclear medicine and interventional radiology . It is common during X-ray practice to use exposure parameters with short times to avoid blurring by the movement of the animal, but the fact that the animals need to be immobilized during the exposures contribute significantly with the increase of the dose received by the professionals, whose biological risks are not yet well established as a result of exposure to other factors harmful to health, such as anesthetic gases, insecticides, zoonoses and others. For this reason, we sought to verify the main radiological risks to which veterinarians are exposed and the best means to guarantee radiological protection

  19. Information warfare technologies in political discourse

    Directory of Open Access Journals (Sweden)

    Karpova Anna Yu.

    2016-01-01

    Full Text Available We attempt to examine the technology of «information warfare» in this paper. The dominant theme of the paper is that the outcome of the information warfare is important not only for the future of a state itself but for the future of the world balance of forces. The main task of geopolitical actors in information warfare is to introduce ideas corresponding to their interests into mass consciousness. All participants of political conflicts have common features in technologies of Information warfare. The information anomie is the indicator of the great geopolitical actors’ personified interests on the stage of «information warfare» - the process resulted in destroying the communicative line: report-information understanding and disrupting the social order in society. In this paper authors describe the following Information Warfare technologies: "Political volcano" technology; "SPIN" technology; "Widening media resource" technology; "specific gravity" technology; "Cold War 2.0" technology and Information cleaningup technology. It is assumed that in the future there will be new instructions on applying technologies of information warfare. To impart perspective to the paper we consider examples, opinions and trends.

  20. Use of inverse spatial conservation prioritization to avoid biological diversity loss outside protected areas.

    Science.gov (United States)

    Kareksela, Santtu; Moilanen, Atte; Tuominen, Seppo; Kotiaho, Janne S

    2013-12-01

    Globally expanding human land use sets constantly increasing pressure for maintenance of biological diversity and functioning ecosystems. To fight the decline of biological diversity, conservation science has broken ground with methods such as the operational model of systematic conservation planning (SCP), which focuses on design and on-the-ground implementation of conservation areas. The most commonly used method in SCP is reserve selection that focuses on the spatial design of reserve networks and their expansion. We expanded these methods by introducing another form of spatial allocation of conservation effort relevant for land-use zoning at the landscape scale that avoids negative ecological effects of human land use outside protected areas. We call our method inverse spatial conservation prioritization. It can be used to identify areas suitable for economic development while simultaneously limiting total ecological and environmental effects of that development at the landscape level by identifying areas with highest economic but lowest ecological value. Our method is not based on a priori targets, and as such it is applicable to cases where the effects of land use on, for example, individual species or ecosystem types are relatively small and would not lead to violation of regional or national conservation targets. We applied our method to land-use allocation to peat mining. Our method identified a combination of profitable production areas that provides the needed area for peat production while retaining most of the landscape-level ecological value of the ecosystem. The results of this inverse spatial conservation prioritization are being used in land-use zoning in the province of Central Finland. © 2013 Society for Conservation Biology.

  1. Chemical composition and biological evaluation of Physalis peruviana root as hepato-renal protective agent.

    Science.gov (United States)

    El-Gengaihi, Souad E; Hassan, Emad E; Hamed, Manal A; Zahran, Hanan G; Mohammed, Mona A

    2013-03-01

    This study was designed to investigate the potential of Physalis peruviana root as a functional food with hepato-renal protective effects against fibrosis. The chemical composition of the plant root suggested the presence of alkaloids, withanolides and flavonoids. Five compounds were isolated and their structures elucidated by different spectral analysis techniques. One compound was isolated from the roots: cuscohygrine. The biological evaluation was conducted on different animal groups; control rats, control treated with ethanolic root extract, CCl(4) group, CCl(4) treated with root extract, and CCl(4) treated with silymarin as a standard herbal drug. The evaluation used the oxidative stress markers malondialdehyde (MDA), superoxide dismutase (SOD), and nitric oxide (NO). The liver function indices; aspartate and alanine aminotransferases (AST & ALT), alkaline phosphatase (ALP), gamma glutamyl transferase (GGT), bilirubin, and total hepatic protein were also estimated. Kidney disorder biomarkers; creatinine, urea, and serum protein were also evaluated. The results suggested safe administration, and improvement of all the investigated parameters. The liver and kidney histopathological analysis confirmed the results. In conclusion, P. peruviana succeeded in protecting the liver and kidney against fibrosis. Further studies are needed to discern their pharmacological applications and clinical uses.

  2. Electronic Warfare (EW) Historical Perspectives and Its Relationship to Information Operations (IO) - Considerations for Turkey

    Science.gov (United States)

    2006-09-01

    Information Operations IW Information Warfare JDAM Joint Direct Attack Munition JRFL Joint Restricted Frequency List JSTARS Joint...through the preparation of the joint restricted frequency list (JRFL), which includes taboo, guarded and protected frequencies. The EC-130H Compass Call

  3. A suggested approach to the selection of chemical and biological protective clothing--meeting industry and emergency response needs for protection against a variety of hazards.

    Science.gov (United States)

    Stull, Jeffrey O

    2004-01-01

    The paper describes the development of a comprehensive decision logic for selection and use of biological and chemical protective clothing (BCPC). The decision logic recognizes the separate areas of BCPC use among emergency, biological, and chemical hazards. The proposed decision logic provides a system for type classifying BCPC in terms of its compliance with existing standards (for emergency applications), the overall clothing integrity, and the material barrier performance. Type classification is offered for garments, gloves, footwear, and eye/face protection devices. On the basis of multiple, but simply designed flowcharts, the type of BCPC appropriate for specific biological and chemical hazards can be selected. The decision logic also provides supplemental considerations for choosing appropriate BCPC features.

  4. N deposition as a threat to the World's protected areas under the Convention on Biological Diversity

    International Nuclear Information System (INIS)

    Bleeker, A.; Hicks, W.K.; Dentener, F.; Galloway, J.; Erisman, J.W.

    2011-01-01

    This paper combines the world's protected areas (PAs) under the Convention on Biological Diversity (CBD), common classification systems of ecosystem conservation status, and current knowledge on ecosystem responses to nitrogen (N) deposition to determine areas most at risk. The results show that 40% (approx. 11% of total area) of PAs currently receive >10 kg N/ha/yr with projections for 2030 indicating that this situation is not expected to change. Furthermore, 950 PAs are projected to receive >30 kg N/ha/yr by 2030 (approx. twice the 2000 number), of which 62 (approx. 11,300 km 2 ) are also Biodiversity Hotspots and G200 ecoregions; with forest and grassland ecosystems in Asia particularly at risk. Many of these sites are known to be sensitive to N deposition effects, both in terms of biodiversity changes and ecosystem services they provide. Urgent assessment of high risk areas identified in this study is recommended to inform the conservation efforts of the CBD. - Highlights: → Significant areas of the Protected Areas Programme under the CBD will likely be under threat of high N deposition levels by the year 2030.→ Approx. 950 PAs are projected to receive N deposition levels of more than 30 kg N/ha/yr by 2030.→ 62 of these sites are also Biodiversity Hotspots and G200 ecoregions, where forest and grassland ecosystems in Asia will be particularly at risk.→ Many of these sites are known to be sensitive to N deposition effects, both in terms of biodiversity changes and ecosystem services they provide → Urgent assessment of high risk areas identified in this study is recommended to inform the conservation efforts of the CBD. - Significant areas of the UNEP Protected Areas Programme under the CBD receive high N deposition rates that are likely to increase in the future, especially in Asia, and may pose a significant threat to biodiversity.

  5. Moltke as a Model for Information Warfare

    National Research Council Canada - National Science Library

    Gallagher, Daniel P

    1998-01-01

    ... with late 20th century Information Warfare (IW). Clausewitz, with his emphasis on concentrating forces for a decisive battle, or Sun Tzu, with his focus on an indirect approach and subduing the enemy without battle, might appear to be more...

  6. Gas Warfare in World War I.

    Science.gov (United States)

    Flintham, A. J.

    1978-01-01

    The effectiveness of gas warfare during World War I was increased by the lack of a basic understanding of the behavior of gases on the part of the soldiers. This was a result of deficiencies in science education. (BB)

  7. Prehistoric ceremonial warfare: beginning of institutionalized violence

    Czech Academy of Sciences Publication Activity Database

    Turek, Jan

    2017-01-01

    Roč. 13, č. 3 (2017), s. 535-548 ISSN 1555-8622 Institutional support: RVO:67985912 Keywords : human aggression * ceremonial warfare * archery symbolism * Neolithic * Chalcolithic * Europe Subject RIV: AC - Archeology, Anthropology, Ethnology OBOR OECD: Archaeology

  8. On Cyber Warfare Command and Control Systems

    National Research Council Canada - National Science Library

    Howes, Norman R; Mezzino, Michael; Sarkesain, John

    2004-01-01

    .... Cyber warfare then becomes a one-sided battle where the attacker makes all the strikes and the target of the attack responds so slowly that the attacker usually gets away without being identified...

  9. Enzymatic Decontamination of Chemical Warfare Agents

    National Research Council Canada - National Science Library

    Raushel, Frank

    2000-01-01

    The primary objective of this research program is the development of a versatile enzyme-based system that is fully optimized for the decontamination, destruction, and detection of know chemical warfare agents...

  10. Mountain Warfare: The Need for Specialist Training

    National Research Council Canada - National Science Library

    Malik, Muhammad

    2003-01-01

    This study focuses on the need for specialist training for mountain warfare. It analyzes the special characteristics of mountain and high altitude terrain which affect conduct of military operations...

  11. Warfare, genocide, and ethnic conflict: a Darwinian approach.

    Science.gov (United States)

    Dimijian, Gregory G

    2010-07-01

    As the 21st century dawns, I reflect on the history of humankind with growing concern about the need to understand the underlying biological and cultural roots of ethnic conflict and warfare. In the many studies of human conflict, innate biological predispositions have been neglected. This article is the third part of a series of seminars for medical residents at the University of Texas Southwestern Medical School at Dallas (see http://adarwinstudygroup.org/). The series starts with in-depth coverage of Darwinian natural and sexual selection, with examples from the domestication of animals and plants and the crisis of antibiotic resistance. The series strives to show how biology has been neglected in the study of the we-they orientation of human behavior, with its devastating consequences. The subject material is profoundly disturbing, as it looks at "human nature" and contrasts the "dark side" of human behavior with the opposite, profoundly caring and loving side.

  12. Insurgent Uprising: An Unconventional Warfare Wargame

    Science.gov (United States)

    2017-12-01

    Cleveland, Charles T. Connett, and Will Irwin. “Unconventional Warfare in the Gray Zone.” Joint Forces Quarterly 80, no. 1 (2016). Work, Robert O...CODE 13. ABSTRACT (maximum 200 words) Today, and in the future, unconventional solutions will present U.S. policymakers with options for dealing...training objectives and will complement existing training exercises. 14. SUBJECT TERMS unconventional warfare, foreign internal defense, direct

  13. Distributed computing environment for Mine Warfare Command

    OpenAIRE

    Pritchard, Lane L.

    1993-01-01

    Approved for public release; distribution is unlimited. The Mine Warfare Command in Charleston, South Carolina has been converting its information systems architecture from a centralized mainframe based system to a decentralized network of personal computers over the past several years. This thesis analyzes the progress Of the evolution as of May of 1992. The building blocks of a distributed architecture are discussed in relation to the choices the Mine Warfare Command has made to date. Ar...

  14. Route survey periodicity for mine warfare

    OpenAIRE

    Coke, Hartwell F.

    2009-01-01

    Approved for public release, distribution unlimited One of the Navy's most long standing challenges has been conquering the mine warfare threat. As mines and mine warfare techniques evolve and become more sophisticated, so does the United States' ability to counter the threat. The United States newest technique for countering a potential mined harbor, or route, is a process known as "change detection." This concept uses previous side scan sonar images of the area prior to a mining event an...

  15. Biological Control beneath the Feet: A Review of Crop Protection against Insect Root Herbivores

    Directory of Open Access Journals (Sweden)

    Alan Kergunteuil

    2016-11-01

    Full Text Available Sustainable agriculture is certainly one of the most important challenges at present, considering both human population demography and evidence showing that crop productivity based on chemical control is plateauing. While the environmental and health threats of conventional agriculture are increasing, ecological research is offering promising solutions for crop protection against herbivore pests. While most research has focused on aboveground systems, several major crop pests are uniquely feeding on roots. We here aim at documenting the current and potential use of several biological control agents, including micro-organisms (viruses, bacteria, fungi, and nematodes and invertebrates included among the macrofauna of soils (arthropods and annelids that are used against root herbivores. In addition, we discuss the synergistic action of different bio-control agents when co-inoculated in soil and how the induction and priming of plant chemical defense could be synergized with the use of the bio-control agents described above to optimize root pest control. Finally, we highlight the gaps in the research for optimizing a more sustainable management of root pests.

  16. Biological Control beneath the Feet: A Review of Crop Protection against Insect Root Herbivores.

    Science.gov (United States)

    Kergunteuil, Alan; Bakhtiari, Moe; Formenti, Ludovico; Xiao, Zhenggao; Defossez, Emmanuel; Rasmann, Sergio

    2016-11-29

    Sustainable agriculture is certainly one of the most important challenges at present, considering both human population demography and evidence showing that crop productivity based on chemical control is plateauing. While the environmental and health threats of conventional agriculture are increasing, ecological research is offering promising solutions for crop protection against herbivore pests. While most research has focused on aboveground systems, several major crop pests are uniquely feeding on roots. We here aim at documenting the current and potential use of several biological control agents, including micro-organisms (viruses, bacteria, fungi, and nematodes) and invertebrates included among the macrofauna of soils (arthropods and annelids) that are used against root herbivores. In addition, we discuss the synergistic action of different bio-control agents when co-inoculated in soil and how the induction and priming of plant chemical defense could be synergized with the use of the bio-control agents described above to optimize root pest control. Finally, we highlight the gaps in the research for optimizing a more sustainable management of root pests.

  17. INSECT AS BIOLOGICAL INDICATOR FROM PROTECTED TO THE DISTURB LANDSCAPE IN CENTRAL JAVA INDONESIA

    Directory of Open Access Journals (Sweden)

    Karuniawan Puji Wicaksono

    2011-02-01

    Full Text Available In the biological science, invertebrate (especially insect diversity is relatively well known. Yet, little study about their interaction with specific land use or specific system function. With the rapid changes of landscape, biodiversity is also changes in response to human impact; due to each organism have the specific interaction with certain environment. In this research, the assessment of insect order in the different landscape types was conducted using several method of trapping to understand the specific pattern of insect which are inhabited the landscape. The objectives of this research were monitored the Insect diversity, its ecological importance to agro-forestry ecosystem, and compare it with other forest type in this area. Another objective was determined the insect characteristic as the indicator of environmental quality on each land-use system (forest, agro-forestry, plantation and monoculture. Monoculture agriculture has the largest number of Lepidoptera and Hemiptera order (herbivore insect dominated while in agro-forest system has the largest number of Diptera and coleoptera order. Protected forest, plantation forest and agro-forestry showed the similar index number which shows the similar ecological services for the insect as their habitat. However, in the monoculture agriculture, there was an unbalance insect composition and high dominance.

  18. On the Probability of Predicting and Mapping Traditional Warfare Measurements to the Cyber Warfare Domain

    CSIR Research Space (South Africa)

    Grobler, M

    2014-07-01

    Full Text Available Cyber warfare is a contentious topic, with no agreement on whether this is a real possibility or an unrealistic extension of the physical battlefield. This article will not debate the validity and legality of the concept of cyber warfare...

  19. Biospheric Life Support - integrating biological regeneration into protection of humans in space.

    Science.gov (United States)

    Rocha, Mauricio; Iha, Koshun

    2016-07-01

    A biosphere stands for a set of biomes (regional biological communities) interacting in a materially closed (though energetically open) ecological system (CES). Earth's biosphere, the thin layer of life on the planet's surface, can be seen as a natural CES- where life "consumables" are regenerated/restored via biological, geological and chemical processes. In Life Sciences, artificial CESs- local ecosystems extracts with varying scales and degrees of closure, are considered convenient/representatives objects of study. For outer space, these concepts have been applied to the issue of life support- a significant consideration as long as distance from Earth increases. In the nineties, growing on the Russian expertise on biological life support, backed by a multidisciplinary science team, the famous Biosphere 2 appeared. That private project innovated, by assembling a set of Earth biomes samples- plus an organic ag one, inside a closed Mars base-like structure, next to 1.5 ha under glass, in Arizona, US. The crew of 8 inside completed their two years contract, though facing setbacks- the system failed, e.g., to produce enough food/air supplies. But their "failures"- if this word can be fairly applied to science endeavors, were as meaningful as their achievements for the future of life support systems (LSS) research. By this period, the Russians had accumulated experience in extended orbital stays, achieving biological outcomes inside their stations- e.g. complete wheat cycles. After reaching the Moon, the US administration decided to change national priorities, putting the space program as part of a "détente" policy, to relieve international tensions. Alongside the US space shuttle program, the Russians were invited to join the new International Space Station (ISS), bringing to that pragmatic project, also their physical/chemical LSS- top air/water regenerative technology at the time. Present US policy keeps the ISS operational, extending its service past its planned

  20. Blaptica dubia as sentinels for exposure to chemical warfare agents - a pilot study.

    Science.gov (United States)

    Worek, Franz; Seeger, Thomas; Neumaier, Katharina; Wille, Timo; Thiermann, Horst

    2016-11-16

    The increased interest of terrorist groups in toxic chemicals and chemical warfare agents presents a continuing threat to our societies. Early warning and detection is a key component for effective countermeasures against such deadly agents. Presently available and near term solutions have a number of major drawbacks, e.g. lack of automated, remote warning and detection of primarily low volatile chemical warfare agents. An alternative approach is the use of animals as sentinels for exposure to toxic chemicals. To overcome disadvantages of vertebrates the present pilot study was initiated to investigate the suitability of South American cockroaches (Blaptica dubia) as warning system for exposure to chemical warfare nerve and blister agents. Initial in vitro experiments with nerve agents showed an increasing inhibitory potency in the order tabun - cyclosarin - sarin - soman - VX of cockroach cholinesterase. Exposure of cockroaches to chemical warfare agents resulted in clearly visible and reproducible reactions, the onset being dependent on the agent and dose. With nerve agents the onset was related to the volatility of the agents. The blister agent lewisite induced signs largely comparable to those of nerve agents while sulfur mustard exposed animals exhibited a different sequence of events. In conclusion, this first pilot study indicates that Blaptica dubia could serve as a warning system to exposure of chemical warfare agents. A cockroach-based system will not detect or identify a particular chemical warfare agent but could trigger further actions, e.g. specific detection and increased protective status. By designing appropriate boxes with (IR) motion sensors and remote control (IR) camera automated off-site warning systems could be realized. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  1. The Impact of Irregular Warfare on the US Army

    National Research Council Canada - National Science Library

    McDonald, III, Roger L

    2006-01-01

    Although the U.S. Army has yet to clearly define irregular warfare, it is imperative that the Army take near-term action to enhance the ability of Soldiers and units to operate effectively in an irregular warfare environment...

  2. Dilemmas of Warfare in Densely Populated Civilian Areas

    OpenAIRE

    Moshe Tamir

    2012-01-01

    This essay attempts to present operational perspectives on conducting warfare in densely populated areas. It also distinguishes between three types of combat within this general category, with the goal of shedding light on this complex type of warfare.

  3. Developing a Biological Condition Gradient for the Protection of Coral Reefs in Guanica Bay

    Science.gov (United States)

    We introduce the application of the Biological Condition Gradient (BCG), a conceptual model that describes how biological attributes of aquatic ecosystems (i.e., biological condition) might change along a gradient of increasing anthropogenic stress (e.g., physical, chemical and b...

  4. A Hypothesis on Biological Protection from Space Radiation Through the Use of New Therapeutic Gases as Medical Counter Measures

    Science.gov (United States)

    Schoenfeld, Michael P.; Ansari, Rafat R.; Nakao, Atsunori; Wink, David

    2012-01-01

    Radiation exposure to astronauts could be a significant obstacle for long duration manned space exploration because of current uncertainties regarding the extent of biological effects. Furthermore, concepts for protective shielding also pose a technically challenging issue due to the nature of cosmic radiation and current mass and power constraints with modern exploration technology. The concern regarding exposure to cosmic radiation is the biological damage it induces. As damage is associated with increased oxidative stress, it is important and would be enabling to mitigate and/or prevent oxidative stress prior to the development of clinical symptoms and disease. This paper hypothesizes a "systems biology" approach in which a combination of chemical and biological mitigation techniques are used conjunctively. It proposes using new, therapeutic, medical gases as both chemical radioprotectors for radical scavenging and biological signaling molecules for management of the body s response to exposure. From reviewing radiochemistry of water, biological effects of CO, H2, NO, and H2S gas, and mechanisms of radiation biology, it is concluded that this approach may have great therapeutic potential for radiation exposure. Furthermore, it also appears to have similar potential for curtailing the pathogenesis of other diseases in which oxidative stress has been implicated including cardiovascular disease, cancer, chronic inflammatory disease, hypertension, ischemia/reperfusion injury, acute respiratory distress syndrome, Parkinson s and Alzheimer s disease, cataracts, and aging.

  5. A hypothesis on biological protection from space radiation through the use of new therapeutic gases as medical counter measures

    Directory of Open Access Journals (Sweden)

    Schoenfeld Michael P

    2012-04-01

    Full Text Available Abstract Radiation exposure to astronauts could be a significant obstacle for long duration manned space exploration because of current uncertainties regarding the extent of biological effects. Furthermore, concepts for protective shielding also pose a technically challenging issue due to the nature of cosmic radiation and current mass and power constraints with modern exploration technology. The concern regarding exposure to cosmic radiation is biological damage that is associated with increased oxidative stress. It is therefore important and would be enabling to mitigate and/or prevent oxidative stress prior to the development of clinical symptoms and disease. This paper hypothesizes a "systems biology" approach in which a combination of chemical and biological mitigation techniques are used conjunctively. It proposes using new, therapeutic, medical gases as chemical radioprotectors for radical scavenging and as biological signaling molecules for management of the body's response to exposure. From reviewing radiochemistry of water, biological effects of CO, H2, NO, and H2S gas, and mechanisms of radiation biology, it can be concluded that this approach may have therapeutic potential for radiation exposure. Furthermore, it also appears to have similar potential for curtailing the pathogenesis of other diseases in which oxidative stress has been implicated including cardiovascular disease, cancer, chronic inflammatory disease, hypertension, ischemia/reperfusion (IR injury, acute respiratory distress syndrome, Parkinson's and Alzheimer's disease, cataracts, and aging. We envision applying these therapies through inhalation of gas mixtures or ingestion of water with dissolved gases.

  6. Cyber Attacks, Information Attacks, and Postmodern Warfare

    Directory of Open Access Journals (Sweden)

    Valuch Jozef

    2017-06-01

    Full Text Available The aim of this paper is to evaluate and differentiate between the phenomena of cyberwarfare and information warfare, as manifestations of what we perceive as postmodern warfare. We describe and analyse the current examples of the use the postmodern warfare and the reactions of states and international bodies to these phenomena. The subject matter of this paper is the relationship between new types of postmodern conflicts and the law of armed conflicts (law of war. Based on ICJ case law, it is clear that under current legal rules of international law of war, cyber attacks as well as information attacks (often performed in the cyberspace as well can only be perceived as “war” if executed in addition to classical kinetic warfare, which is often not the case. In most cases perceived “only” as a non-linear warfare (postmodern conflict, this practice nevertheless must be condemned as conduct contrary to the principles of international law and (possibly a crime under national laws, unless this type of conduct will be recognized by the international community as a “war” proper, in its new, postmodern sense.

  7. ISIL's Hybrid Warfare in Syria & Iraq

    DEFF Research Database (Denmark)

    Sørensen, Heine

    2016-01-01

    of and ability to synchronize various instruments of power with a view to achieving their end-state. With regards to the second part of the problem statement, the analysis demonstrates how ISIL employed horizontal escalation and ambiguity initially, but later on turned to vertical escalation, within the military......The case study specifically seeks to answer the following problem statement: Does ISIL qualify as an actor using hybrid warfare and if so what characterizes their particular use of this type of warfare? Based on an analysis of ISIL’s warfare from August 2012 to August 2016 the chapter argues......, that it is possible to answer the first part of the problem statement in an affirmative way. Hence, ISIL is not only theoretically prone to hybridity by organizational setup, and by the people comprising the organization, but has in fact continuously acted according to a hybrid logic in its prioritization...

  8. Survey on Urban Warfare Augmented Reality

    Directory of Open Access Journals (Sweden)

    Xiong You

    2018-01-01

    Full Text Available Urban warfare has become one of the main forms of modern combat in the twenty-first century. The main reason why urban warfare results in hundreds of casualties is that the situational information of the combatant is insufficient. Accessing information via an Augmented Reality system can elevate combatants’ situational awareness to effectively improve the efficiency of decision-making and reduce the injuries. This paper begins with the concept of Urban Warfare Augmented Reality (UWAR and illuminates the objectives of developing UWAR, i.e., transparent battlefield, intuitional perception and natural interaction. Real-time outdoor registration, information presentation and natural interaction are presented as key technologies of a practical UWAR system. Then, the history and current research state of these technologies are summarized and their future developments are highlighted from three perspectives, i.e., (1 Better integration with Geographic Information System and Virtual Geographic Environment; (2 More intelligent software; (3 More powerful hardware.

  9. Differential biological effects of iodoacetate in mammalian cell lines; radio sensitization and radio protection

    International Nuclear Information System (INIS)

    Yadav, Usha; Anjaria, K.B.; Desai, Utkarsha N.; Chaurasia, Rajesh K.; Shirsath, K.B.; Bhat, Nagesh N.; Balakrishnan, Sreedevi; Sapra, B.K.; Nairy, Rajesha

    2014-01-01

    There are several studies where it has been shown that Iodoacetate (IA) possesses in vivo anti-tumor activity. The fact that it is a model glycolytic inhibitor makes it more interesting. As seen in recent trends, glycolytic inhibitors are emerging as new strategy for cancer therapeutic research taking advantage of glycolytic phenotype of cancerous tissues. IA has been reported to have radioprotective effects in yeast cells and human lymphocytes. Biological effects of IA in response to radiation in mammalian cell lines are not well documented. We screened IA for cytotoxicity using clonogenic assay at different concentrations ranging from 0.1 to 2.5 μg/ml using three different mammalian cell lines; A-549 (human lung carcinoma cell line), MCF-7 (human mammary cancer cell line) and a noncancerous CHO (Chinese hamster ovary cell line). For studying radioprotective/radio sensitizing efficacy, cells were exposed to 4 Gy of 60 Co-γ radiation using a teletherapy source at a dose rate of 1 Gy/min, following which IA post-treatment was carried out. Clonogenic and micronucleus assay were performed to assess radioprotection/sensitization. The results indicated that IA was highly cytotoxic in cancerous cell lines A-549 (IC 50 =1.25 μg/ml) and MCF-7 (IC 50 = 1.9 μg/ml). In contrast, it was totally non-toxic in non-cancerous cell line, viz. CHO, in the same concentration range. In addition, IA exhibited radio protective effect in CHO cell line, whereas in other two cancer cell lines, viz. A-549 and MCF-7, radio sensitizing effect was seen as judged by induction of cell killing and micronuclei. In conclusion, lA, a model glycolytic inhibitor, was found to be selectively cytotoxic in cancer cells as compared to normal cells. Further, it reduced radiation induced damage (micronuclei and cell killing) in normal cells but increased it in cancer cells indicating its potential use in cancer therapy. (author)

  10. Mongol Warfare in the Pre-Dissolution Period »

    Directory of Open Access Journals (Sweden)

    Timothy May

    2015-01-01

    Full Text Available Although the Mongols used many of the tactics and strategies that steppe nomads had used for centuries, the Mongols refined steppe warfare so that this style of warfare reached its apogee during the Mongol Empire. Furthermore, the Mongols developed a style of warfare that made them possibly the greatest military force in history. This work examines several facets of the pre-dissolution period (1200–1260. With the dissolution of the Mongol Empire, Mongol warfare once again changed. In some areas it remained complex while in others it regressed to traditional forces of steppe warfare, still potent but not as effective as the pre-dissolution period.

  11. Developing a Biological Condition Gradient for the Protection of Puerto Rico's Coral Reefs

    Science.gov (United States)

    We introduce the application of the Biological Condition Gradient (BCG) to coral reefs: a conceptual model that describes how biological attributes of coral reef ecosystems might change along a gradient of increasing anthropogenic stress. Under authority of the Clean Water Act, t...

  12. Guiding Warfare to Reach Sustainable Peace

    DEFF Research Database (Denmark)

    Vestenskov, David; Drewes, Line

    The conference report Guiding Warfare to Reach Sustainable Peace constitutes the primary outcome of the conference It is based on excerpts from the conference presenters and workshop discussions. Furthermore, the report contains policy recommendations and key findings, with the ambition of develo......The conference report Guiding Warfare to Reach Sustainable Peace constitutes the primary outcome of the conference It is based on excerpts from the conference presenters and workshop discussions. Furthermore, the report contains policy recommendations and key findings, with the ambition...... of developing best practices in the education and implementation of IHL in capacity building of security forces....

  13. Sensor Systems for Biological Agent Attacks: Protecting Buildings and Military Bases

    Science.gov (United States)

    2004-01-01

    includes not only detection systems but vaccines, therapeutics , collective protection, and other means of protecting personnel in facilities and...attack. An overall biodefense architecture can include medical countermeasures (e.g., vaccines and therapeutics ) as well as personal and collective... Horticulture , aquaculture, seed/grain powders Small area sources, variable Other aerosols Arthropods Cosmopolitan, variable Sewage, stored

  14. MOFwich: Sandwiched Metal-Organic Framework-Containing Mixed Matrix Composites for Chemical Warfare Agent Removal.

    Science.gov (United States)

    Peterson, Gregory W; Lu, Annie X; Hall, Morgan G; Browe, Matthew A; Tovar, Trenton; Epps, Thomas H

    2018-02-28

    This work describes a new strategy for fabricating mixed matrix composites containing layered metal-organic framework (MOF)/polymer films as functional barriers for chemical warfare agent protection. Through the use of mechanically robust polymers as the top and bottom encasing layers, a high-MOF-loading, high-performance-core layer can be sandwiched within. We term this multifunctional composite "MOFwich". We found that the use of elastomeric encasing layers enabled core layer reformation after breakage, an important feature for composites and membranes alike. The incorporation of MOFs into the core layer led to enhanced removal of chemical warfare agents while simultaneously promoting moisture vapor transport through the composite, showcasing the promise of these composites for protection applications.

  15. Comparison of Selected Methods for Individual Decontamination of Chemical Warfare Agents

    OpenAIRE

    Tomas Capoun; Jana Krykorkova

    2014-01-01

    This study addresses the individual decontamination of chemical warfare agents (CWA) and other hazardous substances. The individual decontamination applies to contaminated body surfaces, protective clothing and objects immediately after contamination, performed individually or by mutual assistance using prescribed or improvised devices. The article evaluates the importance of individual decontamination, security level for Fire and Rescue Service Units of the Czech Republic (FRS CR) and demons...

  16. Animal experiments to investigate biological-chemical radiation protection and the therapy of radiolesions

    International Nuclear Information System (INIS)

    Brueckner, V.

    1974-01-01

    The influence of a combined therapy of radiation protection agents and erythropoetin on the radiation-induced suppression of erythropoiesis in mice is studied with the aid of the radioiron utilization test. After whole-body irradiation with 500 R, the erythropoietic system is so severely affected that erythropoetin application alone does not yield any results. AET (significant) and Cysteamin (insignificant), on the other hand, protect the bone marrow to a certain degree. The protected bone marrow provides a better base for erythropoetin therapy than the bone marrow of the irradiated and unprotected animals. Compared to the application of radiation protection agents alone, the combined therapy with AET and erythropoetin increases the radioiron incorporation in the erythrocytes by 7.5% while the therapy with Cysteamin and erythropoetin results in a 19.3% increase. In spite of these methods, however, the radioiron incorporation rate of the control animals was not reached. (BSC/AK) [de

  17. Toward Operational Art in Special Warfare

    Science.gov (United States)

    2016-02-23

    combatant commanders develop special warfare cam- paign options for their theaters that can be integral parts of the national approach. Getting buy -in at...the resistance spawning franchise operations at home or abroad? – Is the resistance attracting funding or other forms of assistance (indigenous

  18. Warfare and the Teaching of History.

    Science.gov (United States)

    Salevouris, Michael J.

    1989-01-01

    Maintains that history teachers must challenge simplistic romantic notions about war. Proposes two approaches to teaching about war: the use of personal war narratives; and examining the relationship between warfare and society. Discusses literature related to these approaches. Contends that only through realistic assessments of war can peace be…

  19. The technical Dimensions of Nuclear Warfare

    International Nuclear Information System (INIS)

    Broda, E.

    1977-01-01

    This text, written by Engelbert Broda in 1977 is about the dimensions of nuclear warfare. Broda describes the devastating effects of the nuclear bombs dropped in 1945 in Hiroshima and Nagasaki and compares these effects with the explosive power of Hydrogen weapons. He also expresses his concerns about another nuclear ware and analyses possible worsening situations like change in the military doctrine. (nowak)

  20. Book Review COMPOSITE WARFARE: THE CONDUCT OF ...

    African Journals Online (AJOL)

    COMPOSITE WARFARE: THE CONDUCT OF. SUCCESSFUL GROUND FORCE. OPERATIONS IN AFRICA. Eeben Barlow. Abel Esterhuyse, PhD. Stellenbosch University. Pinetown: 30 Degrees South Publishers. 2015, 576 pages. ISBN 9781928211761. Africa is still one of the most conflict-ridden places on earth – from ...

  1. MOSES, development of an Underwater Warfare Testbed

    NARCIS (Netherlands)

    Lentze, S.G.

    2001-01-01

    The TNO underwater warfare (UWW) research programme results in a large number of models used in operational research projects. To enhance the accessibility and re-use of these models for new projects, TNO-FEL has developed the modelling environment ‘MOSES - Maritime Operations Simulation and

  2. Biomonitoring of exposure to chemical warfare agents

    NARCIS (Netherlands)

    Noort, D.; Schans, M.J. van der; Benschop, H.P.

    2006-01-01

    An overview is presented of the major methods that are presently available for biomonitoring of exposure to chemical warfare agents, i.e., nerve agents and sulfur mustard. These methods can be applied for a variety of purposes such as diagnosis and dosimetry of exposure of casualties, verification

  3. New Developments in Chinese Strategic Psychological Warfare

    Science.gov (United States)

    2005-01-01

    Taoism , which coupled hardness with softness in warfare, was not the only influence on the theory of psychological operations in ancient China. Other...portraying Islamic martyrs who appear to speak to soldiers from the clouds.38 In contemporary wars, such as the Gulf War, the first targets attacked have

  4. Research in radiation biology, in the environment, and in radiation protection at CRNL

    International Nuclear Information System (INIS)

    Marko, A.M.; Myers, D.K.; Ophel, I.L.; Cowper, G.; Newcombe, H.B.

    1978-01-01

    Research in radiation biology at CRNL is concerned with: evaluation of the effects of low doses of radiation upon humans and other living organisms; the development of new methods for detecting the effects of radiation exposure in large populations; the continued development of improved methods by which radiation levels can be measured accurately and reliably; and evaluation of the effects of nuclear power use upon the environment. The present report summarizes our background knowledge of radiation hazards and describes current research activities in Biology and Health Physics Division at CRNL. (author)

  5. A Predictive Model of Surface Warfare Officer Retention: Factors Affecting Turnover

    National Research Council Canada - National Science Library

    Gjurich, Gregory

    1999-01-01

    Junior Surface Warfare Officer retention is in a crisis. The Surface Warfare Officer community anticipates an inability to fill Department Head billets due to the number of junior Surface Warfare Officers leaving military service...

  6. Introduction of ice protective film for 3D microscale analysis of biological sample

    International Nuclear Information System (INIS)

    Iwanami, T.; Kinoshita, K.; Nojima, M.; Owari, M.

    2008-01-01

    It is urgently necessary for secondary ion mass spectrometry (SIMS) analysis to overcome influence on the compositional distribution of the sample in vacuum chamber. In this study, we investigated the handling of the ice protective film in techniques such as the gallium focused ion beam (Ga FIB) etching. Here we demonstrate the technique with frozen Hymenochirus boettgeri red blood cell. The red blood cells covered with an ice protective film were cross-sectioned by using Ga FIB, and the two-dimensional SIMS mapping over the cross-section was carried out. The distributions of Na and K were observed on the cross-section and surface of red blood cell with ice protective film. This result agrees qualitatively with physiological intracellular and extracellular concentrations of vital cells. The technique used for SIMS was proved to be a reliable method, preserving the cells in their living state.

  7. Radiation protection

    International Nuclear Information System (INIS)

    Koelzer, W.

    1975-01-01

    Physical and radiological terms, quantities, and units. Basic principles of radiation protection (ICRP, IAEA, EURATOM, FRG). Biological effects of ionizing radiation. Objectives of practical radiation protection. (HP) [de

  8. Survey results of corroding problems at biological treatment plants, Stage II Protection of concrete - State of the Art

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, Ylva (CBI, Boraas (Sweden)); Henriksson, Gunilla (SP, Boraas (Sweden))

    2011-07-01

    A pilot study on the degradation and corrosion of concrete in biological treatment plants was conducted in 2009/2010 in a Waste Refinery Project WR-27 'Survey results of corroding problems at biological treatment plants'. The results showed that the concrete does not have sufficient resistance in the current aggressive plant environment. Furthermore, it is stated that some form of surface protection system is needed to ensure the good performance of concrete constructions, and that the system must withstand the aggressive environment and the traffic that occurs on site. Consequently, a new study was proposed in order to develop specifications for surface protection of concrete in aggressive food waste environments. Results from that study are presented in this report. The report includes various types of waterproofing/protection coating for concrete in biological treatment plants. A number of proposals from the industry are presented in the light of results from project WR-27, i.e., the materials must, among other things, withstand the aggressive leachate from waste food at temperatures up to 70 deg C, and some degree of wear. Some systems are compared in terms of technical material properties as reported by the manufacturer. It turns out that different testing methods were used, and the test results are thus generally not directly comparable. A proposal for a test program has been developed, focusing on chemical resistance and wear resistance. A test solution corresponding to leachate is specified. Laboratory tests for verification of the proposed methodology and future requirements are proposed, as well as test sites and follow-up in the field

  9. Vector Biology: Tyrosine Degradation Protects Blood Feeders from Death via La Grande Bouffe

    Czech Academy of Sciences Publication Activity Database

    Kopáček, Petr; Perner, Jan

    2016-01-01

    Roč. 26, č. 16 (2016), R763-R765 ISSN 0960-9822 Institutional support: RVO:60077344 Keywords : tick boophilus-microplus * heme detoxification * pathway * insect Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 8.851, year: 2016

  10. Coral Reef Biological Criteria: Using Clean Water Act to Protect a National Treasure

    Science.gov (United States)

    A collaborative Environmental Protection Agency effort is underway to elucidate the technical aspects of coral reef biocriteria implementation. A stony coral rapid bioassessment protocol has been introduced and applied in the Florida Keys and U.S. Virgin Islands, where several in...

  11. Biological bases of radiological protection criteria for superficial, low penetrating radiation exposure

    Energy Technology Data Exchange (ETDEWEB)

    Charles, M W

    1986-01-01

    When the body is exposed to low penetrating radiation such as beta or low energy X-rays, the skin, eyes and sometimes testes may be the most highly irradiated organs of the body. In order to assess the biological response following such exposures it is necessary to understand the radiobiology of the specific organs and, in particular, the identity and depth of the most radiosensitive cells. This information is also directly relevant to the needs of those responsible for calculating and measuring doses to personnel. Up to date information on the identification and depth of cells at risk, and the biological response following non-uniform exposures will be reviewed. The limitations in this knowledge which are creating problems for dosimetric applications are identified so that radiobiology programmes can then be evaluated and tailored to meet these practical needs.

  12. Radiation protection - Performance criteria for service laboratories performing biological dosimetry by cytogenetics

    International Nuclear Information System (INIS)

    2004-01-01

    This International Standard provides criteria for quality assurance and quality control, evaluation of the performance and the accreditation of biological dosimetry by cytogenetic service laboratories. This International Standard addresses: a) the confidentiality of personal information, for the customer and the service laboratory, b) the laboratory safety requirements, c) the calibration sources and calibration dose ranges useful for establishing the reference dose-effect curves allowing the dose estimation from chromosome aberration frequency, and the minimum detection levels, d) the scoring procedure for unstable chromosome aberrations used for biological dosimetry, e) the criteria for converting a measured aberration frequency into an estimate of absorbed dose, f) the reporting of results, g) the quality assurance and quality control, h) informative annexes containing examples of a questionnaire, instructions for customers, a data sheet for recording aberrations and a sample report

  13. Information operation/information warfare modeling and simulation

    OpenAIRE

    Buettner, Raymond

    2000-01-01

    Information Operations have always been a part of warfare. However, this aspect of warfare is having ever-greater importance as forces rely more and more on information as an enabler. Modern information systems make possible very rapid creation, distribution, and utilization of information. These same systems have vulnerabilities that can be exploited by enemy forces. Information force-on-force is important and complex. New tools and procedures are needed for this warfare arena. As these t...

  14. Protective Effect of Selected Medicinal Plants against Hydrogen Peroxide Induced Oxidative Damage on Biological Substrates

    Directory of Open Access Journals (Sweden)

    Namratha Pai Kotebagilu

    2014-01-01

    Full Text Available Oxidative stress is developed due to susceptibility of biological substrates to oxidation by generation of free radicals. In degenerative diseases, oxidative stress level can be reduced by antioxidants which neutralize free radicals. Primary objective of this work was to screen four medicinal plants, namely, Andrographis paniculata, Costus speciosus, Canthium parviflorum, and Abrus precatorius, for their antioxidant property using two biological substrates—RBC and microsomes. The antioxidative ability of three solvent extracts, methanol (100% and 80% and aqueous leaf extracts, was studied at different concentrations by thiobarbituric acid reactive substances method using Fenton’s reagent to induce oxidation in the substrates. The polyphenol and flavonoid content were analyzed to relate with the observed antioxidant effect of the extracts. The phytochemical screening indicated the presence of flavonoids, polyphenols, tannins, and β-carotene in the samples. In microsomes, 80% methanol extract of Canthium and Costus and, in RBC, 80% methanol extract of Costus showed highest inhibition of oxidation and correlated well with the polyphenol and flavonoid content. From the results it can be concluded that antioxidants from medicinal plants are capable of inhibiting oxidation in biological systems, suggesting scope for their use as nutraceuticals.

  15. Animal experiment studies on biological and chemical radiation protection - the combined effects of serotonin and erythropoletin

    International Nuclear Information System (INIS)

    Sasse, U.

    1975-01-01

    The influence of a prophylactic combination treatment with serotonin and erythropoietin on the inhibited erythropoiesis of whole-body irradiated mice (500 R) was studied. Both erythropoietin and serotonin turned out to compensate the radiation-induced inhibition of the formation rate for erythrocytes to a small extent. However, only the enhancement of erythropoiesis due to serotonin indicated significant values. Yet the combined application of the named substances yielded a distinct and significant effect in radiation protection which even exceeded the simple addition of the protective effect yielded by serotonin and erythropoietin alone. But despite of this considerable success the radiation damage in the erythropoietic system was not even half compensated for. (orig./MG) [de

  16. The cutting process, its harmful effects, the biological behavior of aerosols and possible protective actions

    International Nuclear Information System (INIS)

    Andre, S.; Metivier, H.; Pilot, G.; Pourprix, M.

    1988-01-01

    Most of the cutting methods applied in the industry are thermal or mechanical. The investigations carried out for developing new cutting methods and the criteria taken into account are described. Concerning health protection (most of the contaminations occur by inhalation) it is shown that the physico-chemical properties of the aerosols must be known. The physical characteristics of the gas and aerosols limit the choice of techniques to be applied [fr

  17. A Holistic Approach Including Biological and Geological Criteria for Integrative Management in Protected Areas.

    Science.gov (United States)

    Peña, Lorena; Monge-Ganuzas, Manu; Onaindia, Miren; De Manuel, Beatriz Fernández; Mendia, Miren

    2017-02-01

    Biodiversity hotspots and geosites are indivisible parts of natural heritage. Therefore, an adequate spatial delimitation and understanding of both and their linkages are necessary in order to be able to establish conservation policies. Normally, biodiversity hotspots are a typical target for those policies but, generally, geosites are not taken into account. Thus, this paper aims to fill this gap by providing an easily replicable method for the identification and integration of the geosites and the biodiversity hotspots in a Network for Integrative Nature Conservation that highlights their linkages. The method here presented has been applied to Urdaibai Biosphere Reserve situated in southeastern of the Bay of Biscay. The obtained results indicate that some geosites that are not directly related with biodiversity hotspots remain unprotected. Thus, from the study carried out, it can be stated that we conserving just the biodiversity hotspots is not enough to conserve the whole natural heritage of a protected area, as some plots interesting due to their relevant geoheritage remain unprotected. Therefore, it is necessary to fully integrate geosites into the planning documents of protected areas as a part of an ecosystem approach. The ecosystem approach recognizes the integrity of abiotic and biotic elements in nature conservation policies. Moreover, the proposed framework and the innovative methodology can be used as an easy input to identify priority areas for conservation, to improve the protected areas conservation planning, and to demonstrate the linkages between biodiversity hotspots and geosites.

  18. A Holistic Approach Including Biological and Geological Criteria for Integrative Management in Protected Areas

    Science.gov (United States)

    Peña, Lorena; Monge-Ganuzas, Manu; Onaindia, Miren; De Manuel, Beatriz Fernández; Mendia, Miren

    2017-02-01

    Biodiversity hotspots and geosites are indivisible parts of natural heritage. Therefore, an adequate spatial delimitation and understanding of both and their linkages are necessary in order to be able to establish conservation policies. Normally, biodiversity hotspots are a typical target for those policies but, generally, geosites are not taken into account. Thus, this paper aims to fill this gap by providing an easily replicable method for the identification and integration of the geosites and the biodiversity hotspots in a Network for Integrative Nature Conservation that highlights their linkages. The method here presented has been applied to Urdaibai Biosphere Reserve situated in southeastern of the Bay of Biscay. The obtained results indicate that some geosites that are not directly related with biodiversity hotspots remain unprotected. Thus, from the study carried out, it can be stated that we conserving just the biodiversity hotspots is not enough to conserve the whole natural heritage of a protected area, as some plots interesting due to their relevant geoheritage remain unprotected. Therefore, it is necessary to fully integrate geosites into the planning documents of protected areas as a part of an ecosystem approach. The ecosystem approach recognizes the integrity of abiotic and biotic elements in nature conservation policies. Moreover, the proposed framework and the innovative methodology can be used as an easy input to identify priority areas for conservation, to improve the protected areas conservation planning, and to demonstrate the linkages between biodiversity hotspots and geosites.

  19. Electronic Warfare: Comprehensive Strategy Needed for Suppressing Enemy Air Defenses

    National Research Council Canada - National Science Library

    2001-01-01

    .... To achieve this suppression, the services use specialized aircraft designed to neutralize, destroy, or temporarily degrade enemy air defense systems through either physical attack or electronic warfare...

  20. Are Current Psychological Operations Procedures Adequate in Information Warfare?

    National Research Council Canada - National Science Library

    Duff, Murray

    1997-01-01

    .... While some aspects of information warfare are conducted domestically, many are executed on foreign soil and involve extensive interaction with other governments, their population, non-governmental...

  1. Textile/metal-organic-framework composites as self-detoxifying filters for chemical-warfare agents.

    Science.gov (United States)

    López-Maya, Elena; Montoro, Carmen; Rodríguez-Albelo, L Marleny; Aznar Cervantes, Salvador D; Lozano-Pérez, A Abel; Cenís, José Luis; Barea, Elisa; Navarro, Jorge A R

    2015-06-01

    The current technology of air-filtration materials for protection against highly toxic chemicals, that is, chemical-warfare agents, is mainly based on the broad and effective adsorptive properties of hydrophobic activated carbons. However, adsorption does not prevent these materials from behaving as secondary emitters once they are contaminated. Thus, the development of efficient self-cleaning filters is of high interest. Herein, we report how we can take advantage of the improved phosphotriesterase catalytic activity of lithium alkoxide doped zirconium(IV) metal-organic framework (MOF) materials to develop advanced self-detoxifying adsorbents of chemical-warfare agents containing hydrolysable P-F, P-O, and C-Cl bonds. Moreover, we also show that it is possible to integrate these materials onto textiles, thereby combining air-permeation properties of the textiles with the self-detoxifying properties of the MOF material. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. Computational models of intergroup competition and warfare.

    Energy Technology Data Exchange (ETDEWEB)

    Letendre, Kenneth (University of New Mexico); Abbott, Robert G.

    2011-11-01

    This document reports on the research of Kenneth Letendre, the recipient of a Sandia Graduate Research Fellowship at the University of New Mexico. Warfare is an extreme form of intergroup competition in which individuals make extreme sacrifices for the benefit of their nation or other group to which they belong. Among animals, limited, non-lethal competition is the norm. It is not fully understood what factors lead to warfare. We studied the global variation in the frequency of civil conflict among countries of the world, and its positive association with variation in the intensity of infectious disease. We demonstrated that the burden of human infectious disease importantly predicts the frequency of civil conflict and tested a causal model for this association based on the parasite-stress theory of sociality. We also investigated the organization of social foraging by colonies of harvester ants in the genus Pogonomyrmex, using both field studies and computer models.

  3. Handbook of toxicology of chemical warfare agents

    CERN Document Server

    2010-01-01

    This groundbreaking book covers every aspect of deadly toxic chemicals used as weapons of mass destruction and employed in conflicts, warfare and terrorism. Including findings from experimental as well as clinical studies, this one-of-a-kind handbook is prepared in a very user- friendly format that can easily be followed by students, teachers and researchers, as well as lay people. Stand-alone chapters on individual chemicals and major topics allow the reader to easily access required information without searching through the entire book. This is the first book that offers in-depth coverage of individual toxicants, target organ toxicity, major incidents, toxic effects in humans, animals and wildlife, biosensors, biomarkers, on-site and laboratory analytical methods, decontamination and detoxification procedures, prophylactic, therapeutic and countermeasures, and the role of homeland security. Presents a comprehensive look at all aspects of chemical warfare toxicology in one reference work. This saves research...

  4. Endodontic radiology, practice, and knowledge of radiation biology, hazard, and protection among clinical dental students and interns

    Directory of Open Access Journals (Sweden)

    Joan Emien Enabulele

    2015-01-01

    Full Text Available Objective: To evaluate the practice and knowledge of endodontic radiology as well as assess the knowledge of radiation biology, hazard, and protection among clinical dental students and interns. Materials and Methods: Cross-sectional study of clinical dental students and interns at University of Benin and University of Benin Teaching hospital respectively. Data was collected using a questionnaire which covered practice and knowledge of endodontic radiography, knowledge of radiation biology, hazard, and protection. Data was analyzed using Statistical Package for Social Sciences (SPSS version 17.0. Result: Seventy participants were included in the study, 40% were final year students and 24.3% house officers. Majority (95.7% agreed that they exposed radiographs as part of endodontic treatment. Only 18.6% knew that the apices of teeth should be 3mm from the border of the X-ray film, while 24.3% knew that 3mm of periapical bone should be visible on X-ray. Less than half (31.4% knew that paralleling technique was the technique of choice for endodontic radiography and this was statistically Significant in relationship to the status of the of the respondents. A few (4.3% of the respondents had knowledge of new horizons in endodontic imaging. Half of the respondents knew that damage by X-rays is mainly due to formation of free radicals. The most frequently reported radiation hazards was reduced salivary flow, while the least reported was rampant caries. Most knew how to protect patients, themselves, and other persons while exposing radiographs. Conclusion: There is need for inclusion of endodontic radiography in the undergraduate curriculum to ensure proper and correct radiographs during endodontic procedure.

  5. Mapping the Spread of Mounted Warfare

    Directory of Open Access Journals (Sweden)

    Peter Turchin

    2016-12-01

    Full Text Available Military technology is one of the most important factors affecting the evolution of complex societies. In particular, mounted warfare, the use of horse-riders in military operations, revolutionized war as it spread to different parts of Eurasia and Africa during the Ancient and Medieval eras, and to the Americas during the Early Modern period. Here we use a variety of sources to map this spread.

  6. UML modelling of network warfare examples

    CSIR Research Space (South Africa)

    Veerasamy, N

    2011-08-01

    Full Text Available ] Affects both civilian and military domains [8] [9] Related to the concepts of infowar, information operations, hacking, hackivism, cyberterrorism and cybotage depending on motivations and techniques [10] Encompasses both technological solutions...]. In addition, Williers as well as Qingbao and Anwar discuss more offensive aspects of information security and Network Warfare like Hacking, Vulnerability Injection, Network Attacks, Denial of Capability, Interception and Blockage [6] [18] [19]. Various...

  7. Maritime Trade Warfare Against a Modern Power

    Science.gov (United States)

    2013-05-20

    Malaysian and Singaporean support. Operational Environment The previous sections have assessed that an oil embargo would be effective at influencing...will be addressed. The first approach is to stop the trade at its source. This approach forms the foundation of many contemporary sanctions. Under...antisubmarine warfare capable ships, could be sufficient to defend against forces attempting to break a blockade, and a carrier battle group in the Indian Ocean

  8. Navy Operational Planner - Undersea Warfare Module

    Science.gov (United States)

    2016-09-01

    concepts are considered in NOP–USW that are not in previous research: time phasing of missions, mutually exclusive missions, and asset availability...operational planning efforts. NOP–USW suggests the correct allocation of assets across a wide theater of operation to accomplish missions in the...Master’s thesis 4. TITLE AND SUBTITLE NAVY OPERATIONAL PLANNER – UNDERSEA WARFARE MODULE 5. FUNDING NUMBERS 6. AUTHOR(S) Guy A. Molina 7

  9. Toward Operational Art in Special Warfare: Appendixes

    Science.gov (United States)

    2016-01-01

    language, proficiency in small-unit tactics, and the ability to build and fight alongside indigenous combat formations in a permissive, uncertain, or...counterinsurgency through and with indigenous forces or personnel.”1 The report has four aims: (1) to adapt conventional operational art to the unique...perfect near-real-time situational awareness,” at least at the tactical level of land warfare in complex terrain. But the idea of leveraging information

  10. Improvement of biological decontamination, protective and repair activity against radiation injury

    International Nuclear Information System (INIS)

    Kagawa, Yasuo

    2013-01-01

    Because the protection of human subject from late radiation injury is the final goal of remediation of radioactive contamination of 137 Cs in environment, improvement of DNA-repairing ability and 137 Cs-removal from human body is important. In order to reduce environmental radioactivity in areas exceeding 5 mSv/year in Fukushima prefecture, the cost is estimated to be 118 trillion yen, and there are difficulties in finding place to store 137 Cs-contaminated soils and in 137 Cs-recontamination. The radiation damage of DNA molecule takes place stochastically following linear no threshold model (LNT), but the cancer risk and other late radiation injury from long-term low dose radiation do not follow LNT model if we improve DNA repair and the cell regeneration systems. Indirect effects of radiation damage on DNA mediated by reactive oxygen species (ROS) are prevented by vitamin C, E, carotenoids including lycopene and phytochemicals. ROS is also removed by superoxide dismutases containing Cu, Mn and Z. Direct effects of radiation damage on DNA are repaired by enzyme systems using folic acid, vitamins B 6 and B 12 . In addition, before the radiation injury, absorption of 137 Cs is prevented by taking pectin etc. and excretion of 137 Cs is accelerated by ingesting more K. Finally, early detection of cancer and its removal by detailed health check of radiation-exposed people is needed. Radiation-protecting diet developed to protect astronauts from about 1 mSv per day, will be useful for many workers of atomic power plant as well as people living in the 137 Cs-contaminated areas. (author)

  11. In Situ Biological Contamination Studies of the Moon: Implications for Future Planetary Protection and Life Detection Missions

    Science.gov (United States)

    Glavin, Daniel P.; Dworkin, Jason P.; Lupisella, Mark; Kminek, Gerhard; Rummel, John D.

    2010-01-01

    NASA and ESA have outlined visions for solar system exploration that will include a series of lunar robotic precursor missions to prepare for, and support a human return to the Moon, and future human exploration of Mars and other destinations. One of the guiding principles for exploration is to pursue compelling scientific questions about the origin and evolution of life. The search for life on objects such as Mars will require that all spacecraft and instrumentation be sufficiently cleaned and sterilized prior to launch to ensure that the scientific integrity of extraterrestrial samples is not jeopardized by terrestrial organic contamination. Under the Committee on Space Research's (COSPAR's) current planetary protection policy for the Moon, no sterilization procedures are required for outbound lunar spacecraft, nor is there yet a planetary protection category for human missions. Future in situ investigations of a variety of locations on the Moon by highly sensitive instruments designed to search for biologically derived organic compounds would help assess the contamination of the Moon by lunar spacecraft. These studies could also provide valuable "ground truth" data for Mars sample return missions and help define planetary protection requirements for future Mars bound spacecraft carrying life detection experiments. In addition, studies of the impact of terrestrial contamination of the lunar surface by the Apollo astronauts could provide valuable data to help refine future Mars surface exploration plans for a human mission to Mars.

  12. Using cheminformatics to find simulants for chemical warfare agents

    Energy Technology Data Exchange (ETDEWEB)

    Lavoie, J.; Srinivasan, Sree [Molecular Sciences and Engineering Team, U.S. Army Natick Soldier Research, Development and Engineering Center, 15 Kansas Street, Natick, MA 01760 (United States); Nagarajan, R., E-mail: Ramanathan.Nagarajan@us.army.mil [Molecular Sciences and Engineering Team, U.S. Army Natick Soldier Research, Development and Engineering Center, 15 Kansas Street, Natick, MA 01760 (United States)

    2011-10-30

    Highlights: {yields} Summary of chemical warfare agent (CWA) simulants in current use. {yields} Application of method of molecular similarity to CWA and simulants. {yields} Quantitative metric for CWA-simulant similarity. {yields} Rank ordering of simulants in current use. {yields} Potential of method to identify simulants for emerging agents. - Abstract: Direct experimentation with chemical warfare agents (CWA) to study important problems such as their permeation across protective barrier materials, decontamination of equipment and facilities, or the environmental transport and fate of CWAs is not feasible because of the obvious toxicity of the CWAs and associated restrictions on their laboratory use. The common practice is to use 'simulants,' namely, analogous chemicals that closely resemble the CWAs but are less toxic, with the expectation that the results attained for simulants can be correlated to how the CWAs would perform. Simulants have been traditionally chosen by experts, by means of intuition, using similarity in one or more physical properties (such as vapor pressure or aqueous solubility) or in the molecular structural features (such as functional groups) between the stimulant and the CWA. This work is designed to automate the simulant identification process backed by quantitative metrics, by means of chemical similarity search software routinely used in pharmaceutical drug discovery. The question addressed here is: By the metrics of such software, how similar are traditional simulants to CWAs? That is, what is the numerical 'distance' between each CWA and its customary simulants in the quantitative space of molecular descriptors? The answers show promise for finding close but less toxic simulants for the ever-increasing numbers of CWAs objectively and fast.

  13. Using cheminformatics to find simulants for chemical warfare agents

    International Nuclear Information System (INIS)

    Lavoie, J.; Srinivasan, Sree; Nagarajan, R.

    2011-01-01

    Highlights: → Summary of chemical warfare agent (CWA) simulants in current use. → Application of method of molecular similarity to CWA and simulants. → Quantitative metric for CWA-simulant similarity. → Rank ordering of simulants in current use. → Potential of method to identify simulants for emerging agents. - Abstract: Direct experimentation with chemical warfare agents (CWA) to study important problems such as their permeation across protective barrier materials, decontamination of equipment and facilities, or the environmental transport and fate of CWAs is not feasible because of the obvious toxicity of the CWAs and associated restrictions on their laboratory use. The common practice is to use 'simulants,' namely, analogous chemicals that closely resemble the CWAs but are less toxic, with the expectation that the results attained for simulants can be correlated to how the CWAs would perform. Simulants have been traditionally chosen by experts, by means of intuition, using similarity in one or more physical properties (such as vapor pressure or aqueous solubility) or in the molecular structural features (such as functional groups) between the stimulant and the CWA. This work is designed to automate the simulant identification process backed by quantitative metrics, by means of chemical similarity search software routinely used in pharmaceutical drug discovery. The question addressed here is: By the metrics of such software, how similar are traditional simulants to CWAs? That is, what is the numerical 'distance' between each CWA and its customary simulants in the quantitative space of molecular descriptors? The answers show promise for finding close but less toxic simulants for the ever-increasing numbers of CWAs objectively and fast.

  14. Protection of Shipping: A Forgotten Mission with Many New Challenges

    National Research Council Canada - National Science Library

    Grubb, Michael C

    2006-01-01

    ..." mission status, often leading to devastating losses of shipping when war came. Today, the protection of shipping mission still finds itself behind more high-profile missions such as strike warfare and ballistic missile defense...

  15. Evaluation of the protective and curative role of curcumin and venoruton against biological effects of radiation

    International Nuclear Information System (INIS)

    El-Sayed, N.M.

    2006-01-01

    Curcumin (diferuloyl methane) and venoruton [O-(beta-hydroxyethyl)-rutosides] are powerful antioxidants and are important in protecting the cells from damage. The present study aims to evaluate the role of curcumin alone and curcumin with venoruton on radiation-induced changes in male rats exposed to a dose of 5 Gy gamma irradiation. Experimental analyses were performed 1, 7 and 14 days post-irradiation in all animal groups. Exposure to ionizing radiation resulted in decrease in glutathione content and SOD, G6PD and CPK activities and increase in lactate dehydrogenase and GOT activities and creatinine level. The results obtained showed that treatment of rats with olive oil pre and post-irradiation has significantly minimized radiation-induced changes. Curcumin dissolved in olive oil pre and post-irradiation significantly improved the radiation-induced changes while administration of venoruton with curcumin in olive oil provided a better amelioration. It could be concluded that, curcumin in olive oil plus venoruton showed an obvious protective and curative role against the hazards of gamma radiation in male rats

  16. Exposure Path Perceptions and Protective Actions in Biological Water Contamination Emergencies

    Directory of Open Access Journals (Sweden)

    Michael K. Lindell

    2015-01-01

    Full Text Available This study extends the Protective Action Decision Model, developed to address disaster warning responses in the context of natural hazards, to “boil water” advisories. The study examined 110 Boston residents' and 203 Texas students' expectations of getting sick through different exposure paths for contact with contaminated water. In addition, the study assessed respondents' actual implementation (for residents or behavioral expectations (for students of three different protective actions – bottled water, boiled water, and personally chlorinated water – as well as their demographic characteristics and previous experience with water contamination. The results indicate that people distinguish among the exposure paths, but the differences are small (one-third to one-half of the response scale. Nonetheless, the perceived risk from the exposure paths helps to explain why people are expected to consume (or actually consumed bottled water rather than boiled or personally chlorinated water. Overall, these results indicate that local authorities should take care to communicate the relative risks of different exposure paths and should expect that people will respond to a boil water order primarily by consuming bottled water. Thus, they should make special efforts to increase supplies of bottled water in their communities during water contamination emergencies.

  17. Cytogenetic biological dosimetry in radiological protection: chromosome aberration analysis in human lymphocyties

    International Nuclear Information System (INIS)

    Campos, I.M.A. de.

    1988-01-01

    The effects of ionizing radiation on chromosomes have been know for several decades and dose effect relationships are also fairly well established for several doses and dose rates. Apart from its biological significance, the interpretation of chromosome aberration frequency associated with human exposure to radiation plays an important role in dose assessment, particularly in cases where exposure is though to have occurred but no physical dose monitoring system was present. Based on the cytogenetic data obtained from seven cases of exposure to radiation the aberration frequency have been fitted to the quadratic function Y= αD + βD 2 as the dose response curves from literature. The dose equivalent estimate by frequency of chromosomic aberration found here was compared with 60 Co and 192 Ir already published curves obtained at almost similar dose rate together with some hematological data. (author) [pt

  18. Protecting the Planets from Biological Contamination: The Strange Case of Mars Exploration

    Science.gov (United States)

    Rummel, J. D.; Conley, C. A.

    2015-12-01

    Beyond the Earth's Moon, Mars is the most studied and to some the most compelling target in the solar system. Mars has the potential to have its own native life, and it has environments that appear quite capable of supporting Earth life. As such, Mars is subject to policies intended to keep Earth organisms from growing on Mars, and missions to Mars are controlled to ensure that we know that no Mars life gets to Earth onboard a returning spacecraft. It seems odd, then, that Mars is also the planet on which we have crashed the most (the Moon still owns the overall title), and is still the only body that has had positive results from a life-detection experiment soft-landed on its surface. Mars has very little water, yet it snows on Mars and we have seen regular night-time frosts and near-surface ice on more than half of the planet. Despite strong UV insolation, Mars also has regular dust storms and winds that can cover spacecraft surfaces with dust that itself may be poisonous, but also can protect microbial life from death by UV light. In spite of surface features and minerals that provide ample evidence of surface water in the past, on today's Mars only relatively short, thin lines that lengthen and retract with the seasons provide a hint that there may be water near the surface of Mars today, but the subsurface is almost totally unexplored by instruments needed to detect water, itself. In the face of these contradictions, the implementation of planetary protection requirements to prevent cross contamination has to proceed with the best available knowledge, and in spite of sometimes substantial costs to spacecraft development and operations. In this paper we will review the status of Mars as a potential (hopefully not inadvertent) abode for life, and describe the measures taken in the past and the present to safeguard the astrobiological study of Mars, and project the requirements for Mars planetary protection in a possible future that involves both sample return

  19. NATO Advanced Research Workshop, 19-22 May 1997: Rapid Method for Monitoring the Environment for Biological Hazards

    National Research Council Canada - National Science Library

    1997-01-01

    The NATO Advanced Research Workshop met for the purpose of bringing to light rapid methods for monitoring the environment for biological hazards such as biological warfare agents, naturally occurring...

  20. The Cycle of Warfare - Analysis of an Analytical Model

    DEFF Research Database (Denmark)

    Jensen, Mikkel Storm

    2016-01-01

    by its economic, political and ideological characteristics. With the single assumption of economic rationality in human behaviour, Cycle of Warfare is not only coherent, it is applicable to all entities engaged in competition anywhere in the world at any point in history. The Cycle of Warfare can be used...

  1. Surface Warfare Officers Initial Training For Future Success

    Science.gov (United States)

    2018-03-01

    9 A school is initial rating specific technical training that is given to sailors. 14 Figure 4. Less...NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA MBA PROFESSIONAL REPORT SURFACE WARFARE OFFICERS— INITIAL TRAINING FOR FUTURE SUCCESS March 2018...professional report 4. TITLE AND SUBTITLE SURFACE WARFARE OFFICERS—INITIAL TRAINING FOR FUTURE SUCCESS 5. FUNDING NUMBERS 6. AUTHOR(S) Arron J

  2. Anti-Air Warfare Research for Naval Forces

    NARCIS (Netherlands)

    Bloemen, A.A.F.; Witberg, R.

    2000-01-01

    AAW is a warfare area with wide-spread spectrum. Command and Control Systems, sensors, effectors and electronic warfare are integrated to a system, they influence each other and must eventually be effective in coordinated action. This complexity asks for Operations Research methods to measure

  3. Chemical profiling of chemical warfare agents for forensic purposes

    NARCIS (Netherlands)

    Noort, D.; Reuver, L.P.J. de; Fidder, A.; Tromp, M.; Verschraagen, M.

    2010-01-01

    A program has been initiated towards the chemical profiling of chemical warfare agents, in order to support forensic investigations towards synthesis routes, production sites and suspect chemical suppliers. Within the first stage of the project various chemical warfare agents (VX, sulfur mustard,

  4. Molecular effects of resistance elicitors from biological origin and their potential for crop protection

    Directory of Open Access Journals (Sweden)

    Lea eWiesel

    2014-11-01

    Full Text Available Plants contain a sophisticated innate immune network to prevent pathogenic microbes from gaining access to nutrients and from colonising internal structures. The first layer of inducible response is governed by the plant following the perception of microbe- or modified plant-derived molecules. As the perception of these molecules results in a plant response that can provide efficient resistance towards non-adapted pathogens they can also be described as ‘defence elicitors’. In compatible plant/microbe interactions, adapted microorganisms have means to avoid or disable this resistance response and promote virulence. However, this requires a detailed spatial and temporal response from the invading pathogens. In agricultural practice, treating plants with isolated defence elicitors in the absence of pathogens can promote plant resistance by uncoupling defence activation from the effects of pathogen virulence determinants. The plant responses to plant, bacterial, oomycete or fungal-derived elicitors are not, in all cases, universal and need elucidating prior to the application in agriculture. This review provides an overview of currently known elicitors of biological rather than synthetic origin and places their activity into a molecular context.

  5. The Protective Role of Lettuce oil (Lactuca sativa) against Radiation induced Biological Hazards in Male Rats

    International Nuclear Information System (INIS)

    Abdel-Magied, N.; Ahmed, A.G.

    2011-01-01

    This study was conducted to clarify the potential role of lettuce oil against damages induced in rats due to exposure to gamma radiation. Adult male albino rats (120-150 g) were divided into 4 groups each of 12 animals. The first group was considered control animals. The second group received, via gavages, lettuce oil (200 mg/Kg body weight) for 3 weeks. The third group was subjected to a single dose of 6.5Gy whole body gamma irradiation. The fourth group received lettuce oil for 3 weeks then was exposed to radiation. Blood samples were collected 1 and 7 days post irradiation. Exposure of rats to gamma irradiation caused a significant increase in the level of glucose, total cholesterol (TC), triglycerides (TG), malondialdehyde (MDA) and follicle stimulating hormone (FSH) while a significant decrease was recorded in glutathione content (GSH), superoxide dismutase (SOD) and catalase activities, white blood cells (WBCs), red blood cells (RBCs), haemoglobin content (Hb), haematocrit percentage (Hct%), mean corpuscular volume (MCV), platelets (PLT), leutinizing hormone (LH) and testosterone hormone . In rats treated with lettuce oil then exposed to radiation, the results showed an improvement in all previous parameters. It could be concluded that lettuce oil might reduce the biological hazards in rats induced by gamma irradiation

  6. Protecting buildings from a biological or chemical attack: Actions to take before or during a release

    Energy Technology Data Exchange (ETDEWEB)

    Price, Phillip N.; Sohn, Michael D.; Gadgil, Ashok J.; Delp, William W.; Lorenzetti, David M.; Finlayson, Elizabeth U.; Thatcher, Tracy L.; Sextro, Richard G.; Derby, Elisabeth A.; Jarvis, Sondra A.

    2003-01-29

    This report presents advice on how to operate a building to reduce casualties from a biological or chemical attack, as well as potential changes to the building (e.g. the design of the ventilation system) that could make it more secure. It also documents the assumptions and reasoning behind the advice. The particular circumstances of any attack, such as the ventilation system design, building occupancy, agent type, source strength and location, and so on, may differ from the assumptions made here, in which case actions other than our recommendations may be required; we hope that by understanding the rationale behind the advice, building operators can modify it as required for their circumstances. The advice was prepared by members of the Airflow and Pollutant Transport Group, which is part of the Indoor Environment Department at the Lawrence Berkeley National Laboratory. The group's expertise in this area includes: tracer-gas measurements of airflows in buildings (Sextro, Thatcher); design and operation of commercial building ventilation systems (Delp); modeling and analysis of airflow and tracer gas transport in large indoor spaces (Finlayson, Gadgil, Price); modeling of gas releases in multi-zone buildings (Sohn, Lorenzetti, Finlayson, Sextro); and occupational health and safety experience related to building design and operation (Sextro, Delp). This report is concerned only with building design and operation; it is not a how-to manual for emergency response. Many important emergency response topics are not covered here, including crowd control, medical treatment, evidence gathering, decontamination methods, and rescue gear.

  7. Measurement of the removal sechtion of biological protection concretes in the spectrum of an AmBe source

    International Nuclear Information System (INIS)

    Sandin, C.; Tenrreiro, J.; Desdin, L.; Sarria, P.; Monne, G.; Tellez, E.; Csikai, J

    1992-01-01

    A method to measure the neutron removal cross sections in cuban concrete for biological protection using the average spectrum of a radioisotopic source was developed. The method was verified by the measurements of different materials with know removal cross sections like Pb, paraffin and water. These spetial cuban concrete are elaborated on the basis of arids of limestone, limonite, magnetite, baryte and serpentine. The aim of this work is to contribute to the characterization of those concretes for its use in cuban nuclear installations. In the experiments were used an AmBe source with an strength of 10 6 n/s. and a long counter detector with associated electronics. It can be seen in the table that the concretes of magnetite and limonite have the best shielding properties for neutrons

  8. The Pyramid Trough Wetland: environmental and biological diversity in a newly created Antarctic protected area.

    Science.gov (United States)

    Jungblut, Anne D; Wood, Susanna A; Hawes, Ian; Webster-Brown, Jenny; Harris, Colin

    2012-11-01

    The Pyramid Trough (Lat 78°S) has recently gained protection under the Antarctic Treaty system, owing to its wetland values. Here, we describe the microbial diversity of this system, with emphasis on cyanobacteria, and evaluate environment-biota relationships. Geochemistry separates ponds along hydrological gradients receiving recent inflows of dilute meltwater, from a second group that is rarely inundated and where chemistry is dominated by evaporation. Cyanobacteria-based microbial mats dominated the biota throughout. Mats were characterized by light-microscopy, pigment analysis, automated ribosomal intergenic spacer analysis and 16S rRNA gene clone libraries. A total of 17 morphotypes and 21 ribotypes were identified, mostly Oscillatoriales and several taxa that are usually rare in continental Antarctica, including Chroococcales and scytomin-rich Calothrix/Dichothrix, were abundant. There was a general decline in cyanobacterial diversity with increasing conductivity, but weak support for either differences in community composition between the two groups of ponds or sorting of taxa along the hydrological gradients with the pond groups. This implies a broad environmental tolerance and a prevalence of neutral assembly mechanisms in cyanobacterial communities of Antarctic wetland ecosystems. © 2012 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved.

  9. Destruction of chemical warfare surrogates using a portable atmospheric pressure plasma jet

    Science.gov (United States)

    Škoro, Nikola; Puač, Nevena; Živković, Suzana; Krstić-Milošević, Dijana; Cvelbar, Uroš; Malović, Gordana; Petrović, Zoran Lj.

    2018-01-01

    Today's reality is connected with mitigation of threats from the new chemical and biological warfare agents. A novel investigation of cold plasmas in contact with liquids presented in this paper demonstrated that the chemically reactive environment produced by atmospheric pressure plasma jet (APPJ) is potentially capable of rapid destruction of chemical warfare agents in a broad spectrum. The decontamination of three different chemical warfare agent surrogates dissolved in liquid is investigated by using an easily transportable APPJ. The jet is powered by a kHz signal source connected to a low-voltage DC source and with He as working gas. The detailed investigation of electrical properties is performed for various plasmas at different distances from the sample. The measurements of plasma properties in situ are supported by the optical spectrometry measurements, whereas the high performance liquid chromatography measurements before and after the treatment of aqueous solutions of Malathion, Fenitrothion and Dimethyl Methylphosphonate. These solutions are used to evaluate destruction and its efficiency for specific neural agent simulants. The particular removal rates are found to be from 56% up to 96% during 10 min treatment. The data obtained provide basis to evaluate APPJ's efficiency at different operating conditions. The presented results are promising and could be improved with different operating conditions and optimization of the decontamination process.

  10. Hybrid Warfare Studies and Russia’s Example in Crimea

    Directory of Open Access Journals (Sweden)

    Mehmet Seyfettin EROL

    2015-12-01

    Full Text Available Although Hybrid Warfare is an old concept, theoretical studies in the western countries mainly began in the post-Col War era, focusing on asymmetrical threats against conventional superiority of western countries such as USA or Israel. September 11th attacks and 2006 Israel-Lebanon war played important roles for the evolution of hybrid warfare theories. However, there has not any consensus among scholars on a exact or unique definition of hybrid warfare. Hybrid warfare became one of the main security issues for the West and especially for NATO after the Russia-Ukraine crisis. Russian military strategies, called “hybrid warfare” by the western countries, resulted in the successful annexation of Crimea and, caused a serious security problem for the West resulting important structural and functional changes for the military system of NATO. Russian activities, which have been based on surprise, ambiguity and deniability, presented a unique example for hybrid warfare studies.

  11. War and Medicine in a Culture of Peace. 2. Synopsis of Biological Weapons

    OpenAIRE

    Pierard, Gérald

    2001-01-01

    Biological warfare has a long history. Despite the 1972 international convention and several attempts at biological weapon eradication, some countries and non governmental groups still retain some of these agents. According to their potential use, they belong to bioterrorism or to massive destruction weapons. Any biological warfare put the civilian medical and paramedical assets at the frontline and at high risk for being rapidly contaminated. The prompt recognition of a bioterrorist attack a...

  12. The constitutional protection of trade secrets and patents under the Biologics Price Competition and Innovation Act of 2009.

    Science.gov (United States)

    Epstein, Richard A

    2011-01-01

    The Biologics Price Competition and Innovation Act of 2009 ("Biosimilars Act") is for the field of pharmaceutical products the single most important legislative development since passage of the Drug Price Competition and Patent Term Restoration Act of 1984 ("Hatch-Waxman Act"), on which portions of the Biosimilars Act are clearly patterned. Congress revised section 351 of the Public Health Service Act (PHSA) to create a pathway for FDA approval of "biosimilar" biological products. Each biosimilar applicant is required to cite in its application a "reference product" that was approved on the basis of a full application containing testing data and manufacturing information, which is owned and was submitted by another company and much of which constitutes trade secret information subject to constitutional protection. Because the Biosimilars Act authorizes biosimilar applicants to cite these previously approved applications, the implementation of the new legislative scheme raises critical issues under the Fifth Amendment of the Constitution, pursuant to which private property--trade secrets included--may not be taken for public use, without "just compensation." FDA must confront those issues as it implements the scheme set out in the Biosimilars Act. This article will discuss these issues, after providing a brief overview of the Biosimilars Act and a more detailed examination of the law of trade secrets.

  13. Biological dosimetry in radiological protection: dose response curves elaboration for 60Co and 137Cs

    International Nuclear Information System (INIS)

    Silva, Marcia Augusta da

    1997-01-01

    Ionizing radiation sources for pacific uses are being extensively utilized by modern society and the applications of these sources have raised the probability of the occurrence of accidents. The accidental exposition to radiation creates a necessity of the development of methods to evaluate dose quantity. This data could be obtained by the measurement of damage caused by radiation in the exposed person. The radiation dose can be estimated in exposed persons through physical methods (physical dosimetry) but the biological methods can't be dispensed, and among them, the cytogenetic one that makes use of chromosome aberrations (dicentric and centric ring) formed in peripheral blood lymphocytes (PBL) exposed to ionizing radiation. This method correlates the frequency of radioinduced aberrations with the estimated absorbed dose, as in vitro as in vivo, which is called cytogenetic dosimetry. By the introduction of improved new techniques in culture, in the interpretation of aberrations in the different analysers of slides and by the adoption of different statistical programs to analyse the data, significant differences are observed among laboratories in dose-response curves (calibration curves). The estimation of absorbed dose utilizing other laboratory calibration curves may introduce some uncertainties, so the International Atomic Energy Agency (IAEA) advises that each laboratory elaborates your own dose-response curve for cytogenetic dosimetry. The results were obtained from peripheral blood lymphocytes of the healthy and no-smoking donors exposed to 60 Co and 137 Cs radiation, with dose rate of 5 cGy.min. -1 . Six points of dose were determined 20,50,100,200,300,400 cGy and the control not irradiated. The analysed aberrations were of chromosomic type, dicentric and centric ring. The dose response curve for dicentrics were obtained by frequencies weighted in liner-quadratic mathematic model and the equation resulted were for 60 Co: Y = (3 46 +- 2.14)10 -4 cGy -1 + (3

  14. Evaluation of biologically active substances promoting the development of or protecting against endometrial cancer

    Directory of Open Access Journals (Sweden)

    Cymbaluk-Płoska A

    2018-03-01

    Full Text Available Aneta Cymbaluk-Płoska,1 Anita Chudecka-Głaz,1 Anna Jagodzińska,1 Ewa Pius-Sadowska,2 Agnieszka Sompolska-Rzechuła,3 Bogusław Machaliński,2 Janusz Menkiszak1 1Department of Gynecological Surgery and Gynecological Oncology of Adults and Adolescents, Pomeranian Medical University, Szczecin, Poland; 2General Pathology Department, Pomeranian Medical University, Szczecin, Poland; 3Department of Statistics, West Pomeranian University of Technology, Szczecin, Poland Introduction: Adipose tissue is considered an endocrine organ and produces a number of biologically active substances. Aims: To consider the role that four adipokines – leptin, omentin-1, vaspin, and galectin-3 – play in the diagnosis of endometrium cancer and to investigate the association between serum concentrations of adipose tissue metabolism products and the diagnostics and prognosis in endometrial cancer. Patients and methods: The study included 168 patients with body mass index (BMI >20 kg/m2 admitted due to post-menopausal bleeding. Results: A receiver operating characteristic curves test was performed to determine the diagnostic values of the proteins tested. For leptin and galectin-3 the area under the curve (AUC values were 0.79/0.68, while for vaspin and omentin-1 the AUC values were 0.82/0.86 for all study patients. The final model identified the following independent risk factors: glucose concentration, BMI, waist circumference, leptin, and vaspin concentrations. Diagnostic values of leptin and galectin-3 with regard to differentiation between high (Fédération Internationale de Gynécologie Obstétrique [FIGO] III and IV and low (FIGO I and II stages of clinical tumor advancement and prediction of tumor grading (G1 vs G3 based on the AUC curve were 0.82/0.70 and 0.80/0.74. The AUC values for vaspin and omentin-1 with respect to differentiation between histopathological advancement and grading were 0.86/0.81 and 0.83/0.77, respectively. Significantly lower values of

  15. Optimization of Graphene Sensors to Detect Biological Warfare Agents

    Science.gov (United States)

    2014-03-27

    variations that use detection elements such as glucose, cholesterol, NADH, hydrogen peroxide, nitrites , nitrous oxide and aptamers (such as ssDNA...electrical current [34]. The sensor materials and detection limits listed in Table 1 illustrate the types of processed graphene that can be used to...and a 1% mortality rate for those treated[28]. Gastrointestinal anthrax results when B. anthracis enters the body by eating infected meat and has

  16. Selfishness, warfare and economics; or integration, cooperation and biology

    Directory of Open Access Journals (Sweden)

    Emiliano Jesus Salvucci

    2012-05-01

    Full Text Available The acceptance of Darwin's theory of evolution by natural selection is not complete and it has been pointed out its limitation to explain the complex processes that constitute the transformation of species. The darwinian paradigm had its origin in the free market theories and concepts of Malthus and Spencer. Nature was explained on the basis of market theories moving away from an accurate explanation of natural phenomena. It is common that new discoveries bring about contradictions that are intended to be overcome by adjusting results to the dominant reductionist paradigm using all sorts of gradations and combinations that are admitted for each case. Modern findings represent a challenge to the interpretation of the observations with the Darwinian view of competition and struggle for life as theoretical basis. New holistic interpretations are emerging related with the Net of Life, in which the interconnection of ecosystems constitutes a dynamic and self-regulating biosphere: Viruses are recognized as a macroorganism with a huge collection of genes, most unknown, that constitute the major planet's gene pool with a fundamental role in evolution. The hologenome theory considers an organism and all of its associated symbiotic microbes as a result of symbiopoiesis. Microbes, helmints, that normally are understood as parasites, are cohabitants and they have cohabited with their host and drives the evolution and existence of the partners. Each organism is a result of integration of complex systems. The eukaryotic organism is the result of combination of bacterial, virus and eukaryotic DNA and the interaction of its own genome with the genome of its microbiota resulting in an intertwined metabolism (a superorganism along evolution. These new interpretations are remarkable points to be considered in order to construct a solid theory adjusted to the facts and with less speculations and tortuous semantic traps.

  17. OFFICER AND COMMANDER IN ASYMMETRIC WARFARE OPERATIONS

    Directory of Open Access Journals (Sweden)

    Giuseppe CAFORIO

    2013-01-01

    Full Text Available Starting from the data of a field research conducted among soldiers with asymmetric warfare experiences from nine different countries, the author seeks to identify and shed light on the various problems that officers with command responsibilities had to face during their missions. A picture emerges of feelings and experiences relating to their first impression upon arriving in the theatre, relations with local armed forces, relations with the local population and local authorities, relations with NGOs, relations with other armies, the impact of the rules of engagement (ROEs, training and education, and operational experiences. The paper ends with a discussion of the lessons learned.

  18. Axial Vircator for Electronic Warfare Applications

    Directory of Open Access Journals (Sweden)

    L. Drazan

    2009-12-01

    Full Text Available This paper deals with a high power microwave generator with virtual cathode – vircator in axial release for electronic warfare applications. The classification of directed energy weapons microwave (DEWM is introduced together with basic block diagrams of a particular class of DEWM. In the paper, methods for designing vircator pulsed power supply, axial vircator structure, measurement methods and experimental results are presented. The vircator in electromagnetic ammunition is powered by magneto-cumulative generator and in weapons for defense of objects (WDO, it is powered by Marx generator. The possible applications of a vircator in the DEWM area are discussed.

  19. Electronic warfare receivers and receiving systems

    CERN Document Server

    Poisel, Richard A

    2014-01-01

    Receivers systems are considered the core of electronic warfare (EW) intercept systems. Without them, the fundamental purpose of such systems is null and void. This book considers the major elements that make up receiver systems and the receivers that go in them.This resource provides system design engineers with techniques for design and development of EW receivers for modern modulations (spread spectrum) in addition to receivers for older, common modulation formats. Each major module in these receivers is considered in detail. Design information is included as well as performance tradeoffs o

  20. Development of an automated on-line pepsin digestion-liquid chromatography-tandem mass spectrometry configuration for the rapid analysis of protein adducts of chemical warfare agents

    NARCIS (Netherlands)

    Carol-Visser, J.; van der Schans, M.; Fidder, A.; Huist, A.G.; van Baar, B.L.M.; Irth, H.; Noort, D.

    2008-01-01

    Rapid monitoring and retrospective verification are key issues in protection against and non-proliferation of chemical warfare agents (CWA). Such monitoring and verification are adequately accomplished by the analysis of persistent protein adducts of these agents. Liquid chromatography-mass

  1. Protective

    Directory of Open Access Journals (Sweden)

    Wessam M. Abdel-Wahab

    2013-10-01

    Full Text Available Many active ingredients extracted from herbal and medicinal plants are extensively studied for their beneficial effects. Antioxidant activity and free radical scavenging properties of thymoquinone (TQ have been reported. The present study evaluated the possible protective effects of TQ against the toxicity and oxidative stress of sodium fluoride (NaF in the liver of rats. Rats were divided into four groups, the first group served as the control group and was administered distilled water whereas the NaF group received NaF orally at a dose of 10 mg/kg for 4 weeks, TQ group was administered TQ orally at a dose of 10 mg/kg for 5 weeks, and the NaF-TQ group was first given TQ for 1 week and was secondly administered 10 mg/kg/day NaF in association with 10 mg/kg TQ for 4 weeks. Rats intoxicated with NaF showed a significant increase in lipid peroxidation whereas the level of reduced glutathione (GSH and the activity of superoxide dismutase (SOD, catalase (CAT, glutathione S-transferase (GST and glutathione peroxidase (GPx were reduced in hepatic tissues. The proper functioning of the liver was also disrupted as indicated by alterations in the measured liver function indices and biochemical parameters. TQ supplementation counteracted the NaF-induced hepatotoxicity probably due to its strong antioxidant activity. In conclusion, the results obtained clearly indicated the role of oxidative stress in the induction of NaF toxicity and suggested hepatoprotective effects of TQ against the toxicity of fluoride compounds.

  2. Antiviral Biologic Produced in DNA Vaccine/Goose Platform Protects Hamsters Against Hantavirus Pulmonary Syndrome When Administered Post-exposure.

    Directory of Open Access Journals (Sweden)

    Nicole Haese

    Full Text Available Andes virus (ANDV and ANDV-like viruses are responsible for most hantavirus pulmonary syndrome (HPS cases in South America. Recent studies in Chile indicate that passive transfer of convalescent human plasma shows promise as a possible treatment for HPS. Unfortunately, availability of convalescent plasma from survivors of this lethal disease is very limited. We are interested in exploring the concept of using DNA vaccine technology to produce antiviral biologics, including polyclonal neutralizing antibodies for use in humans. Geese produce IgY and an alternatively spliced form, IgYΔFc, that can be purified at high concentrations from egg yolks. IgY lacks the properties of mammalian Fc that make antibodies produced in horses, sheep, and rabbits reactogenic in humans. Geese were vaccinated with an ANDV DNA vaccine encoding the virus envelope glycoproteins. All geese developed high-titer neutralizing antibodies after the second vaccination, and maintained high-levels of neutralizing antibodies as measured by a pseudovirion neutralization assay (PsVNA for over 1 year. A booster vaccination resulted in extraordinarily high levels of neutralizing antibodies (i.e., PsVNA80 titers >100,000. Analysis of IgY and IgYΔFc by epitope mapping show these antibodies to be highly reactive to specific amino acid sequences of ANDV envelope glycoproteins. We examined the protective efficacy of the goose-derived antibody in the hamster model of lethal HPS. α-ANDV immune sera, or IgY/IgYΔFc purified from eggs, were passively transferred to hamsters subcutaneously starting 5 days after an IM challenge with ANDV (25 LD50. Both immune sera, and egg-derived purified IgY/IgYΔFc, protected 8 of 8 and 7 of 8 hamsters, respectively. In contrast, all hamsters receiving IgY/IgYΔFc purified from normal geese (n=8, or no-treatment (n=8, developed lethal HPS. These findings demonstrate that the DNA vaccine/goose platform can be used to produce a candidate antiviral

  3. Metal Ion-Catalyzed Alcoholysis as a Strategy for the High Loading Destruction of Chemical Warfare Organophosphorus Agents

    Science.gov (United States)

    2013-11-01

    agents (CWAs). Whether these inhibitors are used as pesticides or CWAs, all act in the same way by inhibiting an enzyme (a cholinesterase ), thereby...phosphinate, and phosphonate esters are potent acetylcholinesterase inhibitors that are used as animal and crop protectants and chemical warfare...for these inhibitors are used annually, accounting for 70% of all insecticides used for agriculture, in homes and gardens, and for government

  4. Use of In Situ-Generated Dimethyldioxirane for Inactivation of Biological Agents

    National Research Council Canada - National Science Library

    Wallace, William H; Bushway, Karen E; Miller, Susan D; Delcomyn, Carrie A; Renard, Jean J; Henley, Michael V

    2005-01-01

    ...) at neutral pH, was investigated for inactivation of biological warfare agent simulants. The DMDO solution inactivated bacterial spores, fungal spores, vegetative bacterial cells, viruses, and protein by 7 orders of magnitude in less than 10 min...

  5. Epidemiological and radio-biological studies in high background radiation areas of Kerala coast: implications in radiation protection science and human health

    International Nuclear Information System (INIS)

    Das, Birajalaxmi

    2018-01-01

    Till date, Linear No Threshold hypothesis (LNT) is well accepted in radiation protection science in spite of its limitations. However, dose response studies using multiple biological end points from high-background radiation areas have challenged the linearity. Radio-biological and epidemiological studies from high level natural radiation areas of Kerala coast showed non-linearity as well as efficient repair of DNA damage in HLNRA indicating that dose limits for public exposure needs to be revisited which may have implications in radiation protection science, human health and low dose radiation biology. However, further studies using high throughput approach is required to identify chronic radiation signatures in human population exposed to elevated level of natural background radiation

  6. Back to the future: aerial warfare in Libya

    Directory of Open Access Journals (Sweden)

    João Paulo Nunes Vicente

    2013-05-01

    Full Text Available A century after the first air bomb mission, a new intervention in the same geographic space has made evident the changes in Airpower. The Aerial Warfare in Libya has radically changed the civil war, complying with a UN mission to protect Libyan population, imposing a no-fly zone and an arms embargo. Therefore, Operation Unified Protector became one of the most successful campaigns in the history of NATO. We aim to assess the operational efficiency of Airpower in the conflict in Libya, focusing on the challenges of a War essentially Aerial. Despite the military results and the fact that some political objectives were met, we can identify some concerning trends that, if not shifted, may negatively influence future NATO operations. We do not aim to draw general and universal conclusions on the strategic value of Airpower based on the analysis of a specific case. Above all, we focus on identifying some lessons which have influenced OUP operational efficiency. Thus, we must analyze some factors, such as the scope of objectives, the type of opposing action and aerial strategy used by the coalition and then focus on the challenges arising from the OUP.

  7. Information Warfare: Defining the Legal Response to An Attack

    National Research Council Canada - National Science Library

    Pottorff, James

    1999-01-01

    This paper discusses the difficulty in determining whether an information warfare attack, such as a computer virus, can be treated as an "armed attack" for purposes of national defense under the United Nations charter. As the U.S...

  8. Irregular Warfare: Impact on Future Professional Military Education

    National Research Council Canada - National Science Library

    Paschal, David G

    2006-01-01

    ... to operate effectively in an irregular warfare environment. The utility of a decisive war between nation states continues to decline and will eventually reach critical mass based upon the extreme imbalance of military power and a U.S. monopoly...

  9. FFT Based VLSI Digital One Bit Electronic Warfare Receiver

    National Research Council Canada - National Science Library

    Chien-In, Henry

    1998-01-01

    ... (1 GHz) digital receiver designed for electronic warfare applications. The receiver can process two simultaneous signals and has the potential for fabrication on a single multi-chip module (MCM...

  10. Back to the Basics: An Aviation Solution to Counterinsurgent Warfare

    National Research Council Canada - National Science Library

    Davis, Arthur D

    2005-01-01

    .... By examining past examples of the use of air power in counterinsurgent warfare, this study sheds light on the United States' current failings in both equipment and doctrine as it wages this type of war...

  11. Precision Warfare Enables Interdependent Fires and Maneuver in 2010

    National Research Council Canada - National Science Library

    Smith, John

    1997-01-01

    The U.S. Army is in the midst of a revolution in military affairs (RMA). Significant advancements in informational technologies and precision weapons are providing unprecedented potential for future warfare...

  12. Irregular Warfare: Special Operations Joint Professional Military Education Transformation

    National Research Council Canada - National Science Library

    Cannady, Bryan H

    2008-01-01

    ... on today's battlefront in Afghanistan and Iraq and in the Global War on Terrorism (GWOT). At the forefront of the GWOT and irregular warfare are the United States Special Operations Command (USSOCOM...

  13. Irregular Warfare: New Challenges for Civil-Military Relations

    National Research Council Canada - National Science Library

    Cronin, Patrick M

    2008-01-01

    .... Irregular warfare introduces new complications to what Eliot Cohen has called an unequal dialogue between civilian and military leaders in which civilian leaders hold the true power but must modulate...

  14. Echoes of Chechnya Warfare Resound in Moscow, Quantico

    National Research Council Canada - National Science Library

    Ackerman, Robert

    2000-01-01

    .... thinking about urban warfare. After suffering stunning public defeats just a few years ago, Russian forces applied painful lessons learned then to drive Chechen forces out of their capital city, Grozny, this year...

  15. zero day exploits and national readiness for cyber-warfare

    African Journals Online (AJOL)

    HOD

    A zero day vulnerability is an unknown exploit that divulges security flaws in software before such a flaw is publicly ... Keywords: exploits, zero day, vulnerability, cyberspace, cyber-warfare. 1. ..... industries and companies across the globe. The.

  16. The Role of Airpower in Urban Warfare. An Airman's Perspective

    National Research Council Canada - National Science Library

    Saffold, Timothy

    1998-01-01

    .... This emphasis on surface force employment stifles innovative thought as to how military forces can achieve operational and strategic effects by employing airpower as the key instrument of force in urban warfare...

  17. Fourth Generation Warfare: The Need for a Comprehensive Approach

    National Research Council Canada - National Science Library

    Benton, LeRoy D

    2008-01-01

    .... A definition of Fourth Generation Warfare is developed, based on Col. Thomas X. Hammes' writings. The definition is further developed to show relevance and applicability to current operations in the Long War on Terrorism...

  18. Towards a framework for a network warfare capability

    CSIR Research Space (South Africa)

    Veerasamy, N

    2008-07-01

    Full Text Available . These include the legal issues, ethical dilemmas, technical solutions, financial impact and skill/manpower investment. Logical constraints/implications have been grouped together in the discussion that follows. 5.1.1 Legal Ethical Issues As network warfare... but the underlying causes of crime also needs to be understood. Ethics and morals play a significant role in determining the personality traits of an individual. Users will need to balance ethical dilemmas before engaging in offensive network warfare. Computers...

  19. Structuring Naval Special Warfare junior officer professional military education

    OpenAIRE

    Donovan, Thomas A.

    2007-01-01

    Naval Special Warfare does not currently have a designated career path for an officer that requires professional military education (PME) for SEAL junior officers after the rank of Ensign (O-1) and before the rank of Lieutenant Commander (O-4). There currently is interest in this subject matter at the Naval Special Warfare Command and Center. SEAL officers increasingly hold key leadership positions and influence critical decisions in the execution of national strategy. This growing respo...

  20. Strategy in the Robotic Age: A Case for Autonomous Warfare

    Science.gov (United States)

    2014-09-01

    enabling technology that augments human performance, such as exoskeleton suits, and other complementary fields that make robotics function...philosophy of maneuver warfare with new technologies from the Robotic Age, such as unmanned systems and exoskeleton suits, to present a new warfighting...and Brimley, “20YY,” 12. 49 the exoskeleton suit, but rather that the full benefit of autonomous warfare will be achieved by leveraging mass and

  1. The Manipulation of Human Behavior in Guerrilla Warfare: Can It Enhance U.S. Army Special Forces Guerrilla Warfare Operations?

    National Research Council Canada - National Science Library

    Harris, William

    1997-01-01

    .... Proper integration of psychological communications to manipulate behavior in guerrilla warfare may facilitate the recruiting1 motivation, morale, sustainment and popular support for a guerrilla movement and its cause...

  2. Information Warfare, Threats and Information Security

    Directory of Open Access Journals (Sweden)

    Dmitriy Nikolaevich Bespalov

    2014-01-01

    Full Text Available The article presents the opposite, but dependent on each other's reality - Revolutionary War information,information security goals and objectives of their study within the scheme "challenge-response", methodological and analytical support, the role of elites and the information society in promoting information security. One of the features of contemporaneityis the global spread of ICT, combined with poor governance and other difficulties in the construction of innovation infrastructures that are based on them in some countries. This leads to the reproduction of threats, primarily related to the ability to use ICT for purposes that are inconsistent with the objectives of maintaining international peace and security, compliance with the principles of non-use of force, non-interference in the internal affairs of states, etc. In this regard, include such terms as "a threat of information warfare", "information terrorism" and so forth. Information warfare, which stay in the policy declared the struggle for existence, and relationships are defined in terms of "friend-enemy", "ours-foreign". Superiority over the opponent or "capture of its territory" is the aim of political activity. And information security, serving activities similar process of political control, including a set of components, is a technology until their humanitarian. From the context and the decision itself is the ratio of the achieved results of information and political influence to the target - a positive image of Russia. Bringing its policy in line with the demands of a healthy public opinion provides conductivity of theauthorities initiatives in the country and increases the legitimacy of the Russian Federation actions in the world.

  3. CpG oligodeoxyribonucleotides protect mice from Burkholderia pseudomallei but not Francisella tularensis Schu S4 aerosols.

    Science.gov (United States)

    Rozak, David A; Gelhaus, Herbert C; Smith, Mark; Zadeh, Mojgan; Huzella, Louis; Waag, David; Adamovicz, Jeffrey J

    2010-02-05

    Studies have shown that CpG oligodeoxyribonucleotides (ODN) protect mice from various bacterial pathogens, including Burkholderia pseudomallei and Francisella tularensis live vaccine strain (LVS), when administered before parenteral challenge. Given the potential to develop CpG ODN as a pre-treatment for multiple bacterial biological warfare agents, we examined survival, histopathology, and cytokine data from CpG ODN-treated C57BL/6 mice to determine whether previously-reported protection extended to aerosolized B. pseudomallei 1026b and highly virulent F. tularensis Schu S4 infections. We found that, although CpG ODN protected mice from aerosolized B. pseudomallei challenges, the immunostimulant failed to benefit the animals exposed to F. tularensis Schu S4 aerosols. Our results, which contrast with earlier F. tularensis LVS studies, highlight potential differences in Francisella species pathogenesis and underscore the need to evaluate immunotherapies against human pathogenic species.

  4. Using Agent Based Distillation to Explore Issues Related to Asymmetric Warfare

    Science.gov (United States)

    2009-10-01

    official definition of asymmetric warfare , considering that its use was redundant to irregular warfare [30]. 2 Such as the Lanchester Equations...RTP-MP-MSG-069 23 - 1 Using Agent Based Distillation to Explore Issues Related to Asymmetric Warfare Martin Adelantado, Jean-Michel Mathé...shows that both conventional and asymmetric warfare are characterised by nonlinear behaviours and that engagement is a Complex Adaptive System (CAS

  5. Study on human-factors-engineering properties of reactor maintenance workers with protection suits, (2). Basic research on various biological characteristics in reactor maintenance simulation tests

    Energy Technology Data Exchange (ETDEWEB)

    Yoshino, K; Ishii, K; Nakasa, H [Central Research Inst. of Electric Power Industry, Tokyo (Japan); Shigeta, S

    1980-11-01

    To ensure the safety of reactor maintenance workers and to reduce the radiation exposure through the enhancement of labor efficiency, it is needed to evaluate quantitatively work-stress levels of workers with radiation-protection suits. This paper presents the results of reactor-maintenance simulation tests in which the relationship between the work stress and biological characteristics is investigated for 5 pinds of model works done by testees without protection suits in an artificial climate chamber. Major results obtained are: (1) the selected model works are mostly evaluated to be relatively heavy through the measurement of RMR (Relative Metabolic Rate). (2) biological characteristics such as heart rate and respiratory volume under the model works have close relationship to RMR which is the cumulative quantity in relatively long time, and then they may become the real-time indicator for the work stress level. (3) such biological characteristics are greatly affected by the high-temperature work-environment which is often seen in workers with protection suits.

  6. Transport and Reactivity of Decontaminants to Provide Hazard Mitigation of Chemical Warfare Agents from Materials

    Science.gov (United States)

    2016-06-01

    2013 4. TITLE AND SUBTITLE Transport and Reactivity of Decontaminants to Provide Hazard Mitigation of Chemical Warfare Agents from Materials 5a...directions for future decontamination formulation approaches. 15. SUBJECT TERMS GD HD Decontamination Hazard mitigation VX Chemical warfare agent... DECONTAMINANTS TO PROVIDE HAZARD MITIGATION OF CHEMICAL WARFARE AGENTS FROM MATERIALS 1. INTRODUCTION Decontamination of materials is the

  7. Russian New Art of Hybrid Warfare in Ukraine

    Directory of Open Access Journals (Sweden)

    Rusnáková Soňa

    2017-10-01

    Full Text Available The main aim of this paper is to analyse the annexation of Crimea by the Russian Federation. For the purposes of the paper, the theory of hybrid warfare was chosen as an analytical category. Throughout the paper, the concept of hybrid warfare is examined and applied on case study of Crimean annexation. Hybrid warfare, especially in connection with Russian actions in Crimea has been an intensely debated concept. There is an ongoing debate among scholars concerning the meaning of the concept, its existence and employment by the Russian Federation. This paper showed that the article of Valeriy Gerasimov – the incumbent Chief of the General Staff of the Russian Federation-invoked a new warfare strategy for the Russian Federation which was consequently for the very first time in its full spectre and effectivity employed on case of Crimean annexation in March 2014. Observing the application of the hybrid warfare in practice serves the purposes of countering its further potential application in post-Soviet space and Russian ‘near abroad’.

  8. Numerical simulation of RCS for carrier electronic warfare airplanes

    Directory of Open Access Journals (Sweden)

    Yue Kuizhi

    2015-04-01

    Full Text Available This paper studies the radar cross section (RCS of carrier electronic warfare airplanes. Under the typical naval operations section, the mathematical model of the radar wave’s pitch angle incidence range analysis is established. Based on the CATIA software, considering dynamic deflections of duck wing leading edge flaps, flaperons, horizontal tail, and rudder, as well as aircraft with air-to-air missile, anti-radiation missile, electronic jamming pod, and other weapons, the 3D models of carrier electronic warfare airplanes Model A and Model B with weapons were established. Based on the physical optics method and the equivalent electromagnetic flow method, by the use of the RCSAnsys software, the characteristics of carrier electronic warfare airplanes’ RCS under steady and dynamic flights were simulated under the UHF, X, and S radar bands. This paper researches the detection probability of aircraft by radars under the condition of electronic warfare, and completes the mathematical statistical analysis of the simulation results. The results show that: The Model A of carrier electronic warfare airplane is better than Model B on stealth performance and on discover probability by radar detection effectively.

  9. Investigation of Acute Toxicity of a Chemical Warfare Agent in Kidneys

    Directory of Open Access Journals (Sweden)

    Turgut Topal

    2007-08-01

    Full Text Available One of the most important chemical warfare agents, sulfur mustard (SM causes crucial acute and chronic toxic effects. Lung, skin, eye and kidneys are the most affected organs. In this work, it was investigated if increased nitric oxide (NO and peroxynitrite are involved in nitrogen mustard (NM induced kidney damage. In this experimen, aminoguanidine (AG as inducible nitric oxide synthase (iNOS inhibitor and ebselen as peroxynitrite scavenger were used. NM administration resulted in important oxidant and antioxidant changes as well as tissue damage in kidneys. Therapeutic agents showed significant protection and reduced oxidant parameteres leading to tissue healing was observed. Results of this study suggest that drugs with similar properties can be used to protect kidney damage caused by NM. [TAF Prev Med Bull. 2007; 6(4: 227-232

  10. Investigation of Acute Toxicity of a Chemical Warfare Agent in Kidneys

    Directory of Open Access Journals (Sweden)

    Turgut Topal

    2007-08-01

    Full Text Available One of the most important chemical warfare agents, sulfur mustard (SM causes crucial acute and chronic toxic effects. Lung, skin, eye and kidneys are the most affected organs. In this work, it was investigated if increased nitric oxide (NO and peroxynitrite are involved in nitrogen mustard (NM induced kidney damage. In this experimen, aminoguanidine (AG as inducible nitric oxide synthase (iNOS inhibitor and ebselen as peroxynitrite scavenger were used. NM administration resulted in important oxidant and antioxidant changes as well as tissue damage in kidneys. Therapeutic agents showed significant protection and reduced oxidant parameteres leading to tissue healing was observed. Results of this study suggest that drugs with similar properties can be used to protect kidney damage caused by NM. [TAF Prev Med Bull 2007; 6(4.000: 227-232

  11. Comparison of Selected Methods for Individual Decontamination of Chemical Warfare Agents

    Directory of Open Access Journals (Sweden)

    Tomas Capoun

    2014-06-01

    Full Text Available This study addresses the individual decontamination of chemical warfare agents (CWA and other hazardous substances. The individual decontamination applies to contaminated body surfaces, protective clothing and objects immediately after contamination, performed individually or by mutual assistance using prescribed or improvised devices. The article evaluates the importance of individual decontamination, security level for Fire and Rescue Service Units of the Czech Republic (FRS CR and demonstrates some of the devices. The decontamination efficiency of selected methods (sorbent, glove and sponge, two-chamber foam device and wiping with alcohol was evaluated for protective clothing and painted steel plate contaminated with O-ethyl-S-(diisopropylaminoethyl-methylthiophosphonate (VX, sulfur mustard, o-cresol and acrylonitrile. The methods were assessed from an economic point of view and with regard to specific user parameters, such as the decontamination of surfaces or materials with poor accessibility and vertical surfaces, the need for a water rinse as well as toxic waste and its disposal.

  12. Antiradiation UV Vaccine: UV Radiation, Biological effects, lesions and medical management - immune-therapy and immune-protection.

    Science.gov (United States)

    Popov, Dmitri; Jones, Jeffrey; Maliev, Slava

    rabbits, 11-12 months old, live weight 3.5-3.7 (n=11), Balb mice, 2-3 months old, live weight 20-22 g (n=33), Wistar rats, 3-4 months old, live weight 180-220 g(n=33). The studies were approved by the Animal Care and Use Committee for ethical animal research equivalent, at each institution. Seven rabbits, ten mice, eleven Wistar rats were vaccinated with a UV antiradiation vaccine. A second group of animals was used as biological control which received vaccine but no UV Radiation and a third group of animals was used as control without any interventions. Before and after UV Radiation, Vaccination with the UV antiradiation vaccine were provided 17 days prior to UV exposure. The animals were irradiated by a DRT-1 UV generator lamp. The dose of irradiation for laboratory, experimental animals was 10-12 * Standard Erythema Dose (SED) at L=283,7 Laboratory animals were placed in to the box with ventilation. Results: Ultraviolet irradiation of the skin was performed with high doses and causes an inflammation or erythema in all experimental animals. However the grade of skin damage and inflammation was significantly different between animals protected by vaccination and non-protected, non-vaccinated animals. Animals UV-irradiated, but who did not receive the antiradiation vaccine suffered from extensive UV skin burns of second or third degree (grade 2-3). However, animals protected with the UV antiradiation vaccine demonstrated much mild forms of skin cellular injury - mainly erythema, first degree skin burns and a few small patches with second degree skin burns (grade 1-2). Discussion: The severity of skin damage depended on area of exposed skin, time and dose of UV irradiation. Skin injury could be divided into 4 major grades: 1. Faint erythema with dry desquamation. 2. Moderate to severe erythema. 3. Severe erythema with blistering, moist desquamation. 4. Toxic epidermal necrolysis. Mild doses of UV radiation and ionizing radiation can induce cell death by apoptosis and

  13. [Decontamination of chemical warfare agents by photocatalysis].

    Science.gov (United States)

    Hirakawa, Tsutomu; Mera, Nobuaki; Sano, Taizo; Negishi, Nobuaki; Takeuchi, Koji

    2009-01-01

    Photocatalysis has been widely applied to solar-energy conversion and environmental purification. Photocatalyst, typically titanium dioxide (TiO(2)), produces active oxygen species under irradiation of ultraviolet light, and can decompose not only conventional pollutants but also different types of hazardous substances at mild conditions. We have recently started the study of photocatalytic decontamination of chemical warfare agents (CWAs) under collaboration with the National Research Institute of Police Science. This article reviews environmental applications of semiconductor photocatalysis, decontamination methods for CWAs, and previous photocatalytic studies applied to CWA degradation, together with some of our results obtained with CWAs and their simulant compounds. The data indicate that photocatalysis, which may not always give a striking power, certainly helps detoxification of such hazardous compounds. Unfortunately, there are not enough data obtained with real CWAs due to the difficulty in handling. We will add more scientific data using CWAs in the near future to develop useful decontamination systems that can reduce the damage caused by possible terrorism.

  14. Multifunctional ultra-high vacuum apparatus for studies of the interactions of chemical warfare agents on complex surfaces

    International Nuclear Information System (INIS)

    Wilmsmeyer, Amanda R.; Morris, John R.; Gordon, Wesley O.; Mantooth, Brent A.; Lalain, Teri A.; Davis, Erin Durke

    2014-01-01

    A fundamental understanding of the surface chemistry of chemical warfare agents is needed to fully predict the interaction of these toxic molecules with militarily relevant materials, catalysts, and environmental surfaces. For example, rules for predicting the surface chemistry of agents can be applied to the creation of next generation decontaminants, reactive coatings, and protective materials for the warfighter. Here, we describe a multifunctional ultra-high vacuum instrument for conducting comprehensive studies of the adsorption, desorption, and surface chemistry of chemical warfare agents on model and militarily relevant surfaces. The system applies reflection-absorption infrared spectroscopy, x-ray photoelectron spectroscopy, and mass spectrometry to study adsorption and surface reactions of chemical warfare agents. Several novel components have been developed to address the unique safety and sample exposure challenges that accompany the research of these toxic, often very low vapor pressure, compounds. While results of vacuum-based surface science techniques may not necessarily translate directly to environmental processes, learning about the fundamental chemistry will begin to inform scientists about the critical aspects that impact real-world applications

  15. Multifunctional ultra-high vacuum apparatus for studies of the interactions of chemical warfare agents on complex surfaces.

    Science.gov (United States)

    Wilmsmeyer, Amanda R; Gordon, Wesley O; Davis, Erin Durke; Mantooth, Brent A; Lalain, Teri A; Morris, John R

    2014-01-01

    A fundamental understanding of the surface chemistry of chemical warfare agents is needed to fully predict the interaction of these toxic molecules with militarily relevant materials, catalysts, and environmental surfaces. For example, rules for predicting the surface chemistry of agents can be applied to the creation of next generation decontaminants, reactive coatings, and protective materials for the warfighter. Here, we describe a multifunctional ultra-high vacuum instrument for conducting comprehensive studies of the adsorption, desorption, and surface chemistry of chemical warfare agents on model and militarily relevant surfaces. The system applies reflection-absorption infrared spectroscopy, x-ray photoelectron spectroscopy, and mass spectrometry to study adsorption and surface reactions of chemical warfare agents. Several novel components have been developed to address the unique safety and sample exposure challenges that accompany the research of these toxic, often very low vapor pressure, compounds. While results of vacuum-based surface science techniques may not necessarily translate directly to environmental processes, learning about the fundamental chemistry will begin to inform scientists about the critical aspects that impact real-world applications.

  16. Multifunctional ultra-high vacuum apparatus for studies of the interactions of chemical warfare agents on complex surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Wilmsmeyer, Amanda R.; Morris, John R. [Department of Chemistry, Virginia Tech, Blacksburg, Virginia 24061 (United States); Gordon, Wesley O.; Mantooth, Brent A.; Lalain, Teri A. [Research and Technology Directorate, U.S. Army Edgewood Chemical Biological Center, Aberdeen Proving Ground, Maryland 21010 (United States); Davis, Erin Durke [OptiMetrics, Inc., Abingdon, Maryland 21009 (United States)

    2014-01-15

    A fundamental understanding of the surface chemistry of chemical warfare agents is needed to fully predict the interaction of these toxic molecules with militarily relevant materials, catalysts, and environmental surfaces. For example, rules for predicting the surface chemistry of agents can be applied to the creation of next generation decontaminants, reactive coatings, and protective materials for the warfighter. Here, we describe a multifunctional ultra-high vacuum instrument for conducting comprehensive studies of the adsorption, desorption, and surface chemistry of chemical warfare agents on model and militarily relevant surfaces. The system applies reflection-absorption infrared spectroscopy, x-ray photoelectron spectroscopy, and mass spectrometry to study adsorption and surface reactions of chemical warfare agents. Several novel components have been developed to address the unique safety and sample exposure challenges that accompany the research of these toxic, often very low vapor pressure, compounds. While results of vacuum-based surface science techniques may not necessarily translate directly to environmental processes, learning about the fundamental chemistry will begin to inform scientists about the critical aspects that impact real-world applications.

  17. Applicability of federal and state hazardous waste regulatory programs to waste chemical weapons and chemical warfare agents.; TOPICAL

    International Nuclear Information System (INIS)

    Haffenden, R.; Kimmell, T.

    2002-01-01

    This report reviews federal and state hazardous waste regulatory programs that govern the management of chemical weapons or chemical warfare agents. It addresses state programs in the eight states with chemical weapon storage facilities managed by the U.S. Army: Alabama, Arkansas, Colorado, Indiana, Kentucky, Maryland, Oregon, and Utah. It also includes discussions on 32 additional states or jurisdictions with known or suspected chemical weapons or chemical warfare agent presence (e.g., disposal sites containing chemical agent identification sets): Alaska, Arizona, California, Florida, Georgia, Hawaii, Idaho, Illinois, Iowa, Kansas, Louisiana, Massachusetts, Michigan, Mississippi, Missouri, Nebraska, Nevada, New Jersey, New Mexico, New York, North Carolina, Ohio, Pennsylvania, South Carolina, South Dakota, Tennessee, Texas, the U.S. Virgin Islands, Virginia, Washington, Washington, D.C., and Wyoming. Resource Conservation and Recovery Act (RCRA) hazardous waste programs are reviewed to determine whether chemical weapons or chemical warfare agents are listed hazardous wastes or otherwise defined or identified as hazardous wastes. Because the U.S. Environmental Protection Agency (EPA) military munitions rule specifically addresses the management of chemical munitions, this report also indicates whether a state has adopted the rule and whether the resulting state regulations have been authorized by EPA. Many states have adopted parts or all of the EPA munitions rule but have not yet received authorization from EPA to implement the rule. In these cases, the states may enforce the adopted munitions rule provisions under state law, but these provisions are not federally enforceable

  18. A review of multi-threat medical countermeasures against chemical warfare and terrorism.

    Science.gov (United States)

    Cowan, Fred M; Broomfield, Clarence A; Stojiljkovic, Milos P; Smith, William J

    2004-11-01

    The Multi-Threat Medical Countermeasure (MTMC) hypothesis has been proposed with the aim of developing a single countermeasure drug with efficacy against different pathologies caused by multiple classes of chemical warfare agents. Although sites and mechanisms of action and the pathologies caused by different chemical insults vary, common biochemical signaling pathways, molecular mediators, and cellular processes provide targets for MTMC drugs. This article will review the MTMC hypothesis for blister and nerve agents and will expand the scope of the concept to include other chemicals as well as briefly consider biological agents. The article will also consider how common biochemical signaling pathways, molecular mediators, and cellular processes that contribute to clinical pathologies and syndromes may relate to the toxicity of threat agents. Discovery of MTMC provides the opportunity for the integration of diverse researchers and clinicians, and for the exploitation of cutting-edge technologies and drug discovery. The broad-spectrum nature of MTMC can augment military and civil defense to combat chemical warfare and chemical terrorism.

  19. Weeds of Hawaii’s lands devoted to watershed protection and biodiversity conservation: Role of biological control as the missing piece in an integrated pest management strategy

    Science.gov (United States)

    Medeiros, Arthur C.; Loope, L.L.

    2011-01-01

    Despite Hawaii’s reputation as an extinction icon, significant biological resources remain, especially in watersheds, natural areas, and specialized edaphic sites (e.g., lava dry forest, coastal). While direct habitat destruction by humans continues, human-facilitated biological invaders are currently the primary agents of continuing degradation. The ability of invasive plants to have prolific seed production, efficient dispersal systems, and to become established in dense vegetation, complicated by Hawaii’s rugged topography, appears to render mechanical and chemical control as mere holding actions. Costly, ‘environmentally unfriendly’, and often ineffective, strategies using chemical and mechanical control on a large scale, despite the most valiant of efforts, can be viewed simply as attempts to buy time. Without increased levels of safely tested biological control, the seemingly inevitable result is the landscape level transformation of native forests, with potentially catastrophic consequences to cultural, biological, water, and economic resources. Increased levels of effective biological control for certain intractable invasive species appear to comprise a conspicuous ‘missing piece’ in our efforts to protect Hawaiian watersheds and other conservation lands.

  20. Reevaluation of 1999 Health-Based Environmental Screening Levels (HBESLs) for Chemical Warfare Agents

    Energy Technology Data Exchange (ETDEWEB)

    Watson, Annetta Paule [ORNL; Dolislager, Fredrick G [ORNL

    2007-05-01

    This report evaluates whether new information and updated scientific models require that changes be made to previously published health-based environmental soil screening levels (HBESLs) and associated environmental fate/breakdown information for chemical warfare agents (USACHPPM 1999). Specifically, the present evaluation describes and compares changes that have been made since 1999 to U.S. Environmental Protection Agency (EPA) risk assessment models, EPA exposure assumptions, as well as to specific chemical warfare agent parameters (e.g., toxicity values). Comparison was made between screening value estimates recalculated with current assumptions and earlier health-based environmental screening levels presented in 1999. The chemical warfare agents evaluated include the G-series and VX nerve agents and the vesicants sulfur mustard (agent HD) and Lewisite (agent L). In addition, key degradation products of these agents were also evaluated. Study findings indicate that the combined effect of updates and/or changes to EPA risk models, EPA default exposure parameters, and certain chemical warfare agent toxicity criteria does not result in significant alteration to the USACHPPM (1999) health-based environmental screening level estimates for the G-series and VX nerve agents or the vesicant agents HD and L. Given that EPA's final position on separate Tier 1 screening levels for indoor and outdoor worker screening assessments has not yet been released as of May 2007, the study authors find that the 1999 screening level estimates (see Table ES.1) are still appropriate and protective for screening residential as well as nonresidential sites. As such, risk management decisions made on the basis of USACHPPM (1999) recommendations do not require reconsideration. While the 1999 HBESL values are appropriate for continued use as general screening criteria, the updated '2007' estimates (presented below) that follow the new EPA protocols currently under development

  1. Lanchester-Type Models of Warfare, Volume II

    OpenAIRE

    Taylor, James G.

    1980-01-01

    This monograph is a comprehensive treatist on Lanchester-type models of warfare, i.e. differential-equation models of attrition in force-on-force combat operations. Its goal is to provide both an introduction to and current-state-of-the-art overview of Lanchester-type models of warfare as well as a comprehensive and unified in-depth treatment of them. Both deterministic as well as stochastic models are considered. Such models have been widely used in the United States and elsewhere for the...

  2. Theory of information warfare: basic framework, methodology and conceptual apparatus

    Directory of Open Access Journals (Sweden)

    Олександр Васильович Курбан

    2015-11-01

    Full Text Available It is conducted a comprehensive theoretical study and determine the basic provisions of the modern theory of information warfare in on-line social networks. Three basic blocks, which systematized the theoretical and methodological basis of the topic, are established. There are information and psychological war, social off-line and on-line network. According to the three blocks, theoretical concepts are defined and methodological substantiation of information processes within the information warfare in the social on-line networks is formed

  3. Hybrid warfare of the USA in South America

    Directory of Open Access Journals (Sweden)

    A. V. Budaev

    2015-01-01

    Full Text Available Washington’s hybrid warfare in Latin American region differs by its inventive and sophisticated methods and in fact represents a complex and multidimensional phenomenon including symbiosis of the “soft” and “hard” power as well as their combination in the form of the “smart power”. The increasing importance of hybrid warfare technologies in the US foreign policy in Latin America predetermines the necessity of thorough studies and analysis of this phenomenon for providing Russian interests.

  4. IMS software developments for the detection of chemical warfare agent

    Science.gov (United States)

    Klepel, ST.; Graefenhain, U.; Lippe, R.; Stach, J.; Starrock, V.

    1995-01-01

    Interference compounds like gasoline, diesel, burning wood or fuel, etc. are presented in common battlefield situations. These compounds can cause detectors to respond as a false positive or interfere with the detector's ability to respond to target compounds such as chemical warfare agents. To ensure proper response of the ion mobility spectrometer to chemical warfare agents, two special software packages were developed and incorporated into the Bruker RAID-1. The programs suppress interferring signals caused by car exhaust or smoke gases resulting from burning materials and correct the influence of variable sample gas humidity which is important for detection and quantification of blister agents like mustard gas or lewisite.

  5. Conference on soldiers, civilians and environment protection against contaminations

    International Nuclear Information System (INIS)

    1994-01-01

    The military and civil aspects of radiation protection have been discussed. The special emphasize has been done on contamination monitoring of environment, soldier radiological protection during hypothetical warfare, radiological health hazard assessment, post Chernobyl contamination control of environment and food products in Poland, dose equivalent estimation and radiometric control equipment used in military and civil service

  6. THz waves: biological effects, industrial and medical applications. Meeting of the non-ionizing radiation section of the French radiation protection society (SFRP). Conference review

    International Nuclear Information System (INIS)

    Souques, M.; Magne, I.

    2011-01-01

    Following the debates about body scanners installed in airports for passengers security control, the non-ionizing radiations (NIR) section of the French radiation protection society (SFRP) has organized a conference day to take stock of the present day knowledge about the physical aspects and the biological effects of this frequency range as well as about their medical, and industrial applications (both civil and military). This document summarizes the content of the different presentations: THz spectro-imaging technique: status and perspectives (P. Mounaix); THz technology: seeing the invisible? (J.P. Caumes); interaction of millimeter waves with living material: from dosimetry to biological impacts (Y. Le Drean and M. Zhadobov); Tera-Hertz: biological and medical applications (G. Gallot); Tera-Hertz: standards and recommendations (B. Veyret); Biological applications of THz radiation: a review of events and a glance to the future (G.P. Gallerano); Industrial and military applications - liquids and solids detection in the THz domain (F. Garet); THz radiation and its civil and military applications - gas detection and quantifying (G. Mouret); Body scanners and civil aviation security (J.C. Guilpin). (J.S.)

  7. Progress and challenges of protecting North American ash trees from the emerald ash borer using biological control

    Science.gov (United States)

    Jian Duan; Leah Bauer; Roy van Driesche; Juli. Gould

    2018-01-01

    After emerald ash borer (EAB), Agrilus planipennis Fairmaire, was discovered in the United States, a classical biological control program was initiated against this destructive pest of ash trees (Fraxinus spp.). This biocontrol program began in 2007 after federal regulatory agencies and the state of Michigan approved release of...

  8. Protecting America's economy, environment, health, and security against invasive species requires a strong federal program in systematic biology

    Science.gov (United States)

    Hilda Diaz-Soltero; Amy Y. Rossman

    2011-01-01

    Systematics is the science that identifies and groups organisms by understanding their origins, relationships, and distributions. It is fundamental to understanding life on earth, our crops, wildlife, and diseases, and it provides the scientific foundation to recognize and manage invasive species. Protecting America's economy, environment, health, and security...

  9. Nanostructured Metal Oxides for Stoichiometric Degradation of Chemical Warfare Agents

    Czech Academy of Sciences Publication Activity Database

    Štengl, Václav; Henych, Jiří; Janos, P.; Skoumal, M.

    2016-01-01

    Roč. 236, č. 2016 (2016), s. 239-258 ISSN 0179-5953 R&D Projects: GA ČR(CZ) GAP106/12/1116 Institutional support: RVO:61388980 Keywords : chemical warfare agent * metal nanoparticle * unique surface- chemistry * mesoporous manganese oxide Subject RIV: CA - Inorganic Chemistry Impact factor: 3.930, year: 2016

  10. The Role of Civil Affairs in Unconventional Warfare

    Science.gov (United States)

    2012-12-01

    neighbor to the west, and secured the eastern border of Laos 32 Mao Tse -Tung, On Guerrilla Warfare...INTRODUCTION..........................................................................................19  B.  BRIEF HISTORY OF LAOS ...Royal Lao Army SCA Support to Civil Administration SCIRI Supreme Council of Iraq SG Shadow Government SOF Special Operations Forces TAI Targeted

  11. Management information systems for electronic warfare command and decision support

    CSIR Research Space (South Africa)

    Van Niekerk, B

    2015-04-01

    Full Text Available information to allow them to manage their own spectrum, to identify threats, and to deny adversaries’ use of the spectrum. In this paper, the concepts of integrated electronic warfare and spectrum battle management are introduced, and the relevant information...

  12. Manoeuvre warfare analysis of South Africa's 1914-1915 German ...

    African Journals Online (AJOL)

    The study reported in this article explored the nexus between military theory and history. Military theory attempts to quantify, qualify and illuminate the often unpredictable phenomenon of war. The article consists of two parts: the theory of manoeuvre warfare and the history of the 1914-1915 South African campaign in ...

  13. blitzkrieg to desert storm: the evolution of operational warfare

    African Journals Online (AJOL)

    a_nabb

    disease of stalemates infecting militaries before the Second World War. The invasion did not change the world; instead, it brought about an increased awareness of the importance of the operational level of war, a dimension of warfare previously neglected. The German operational effectiveness represented an evolution ...

  14. A identification system for chemical warfare agents with PGNAA method

    International Nuclear Information System (INIS)

    Wang Bairong; Yin Guanghua; Yang Zhongping

    2006-01-01

    The principle and the experimental commanding of Chemical warfare Agents Identification with PGNAA method are discussed in this paper. The choosing of Detector, neutron source and the data processing method are detailed. Finally, a set of experimental instruments composed of Cf-232 and BGO detector is developed based on the theory discussed above. (authors)

  15. Identification system for chemical warfare agents with PGNAA method

    International Nuclear Information System (INIS)

    Wang Bairong; Yin Guanghua; Yang Zhongpin

    2007-01-01

    The principle and the experimental commanding of Chemical warfare Agents Identification with PGNAA method are discussed in this paper. The choosing of detector, neutron source and the data processing method are detailed. Finally, a set of experimental instruments composed of Cf-232 and BGO detector is developed based on this theory discussed above. (authors)

  16. Biomonitoring of exposure to chemical warfare agents: A review

    NARCIS (Netherlands)

    Noort, D.; Benschop, H.P.; Black, R.M.

    2002-01-01

    In this report an overview of the methods currently available for detection of exposure to a number of chemical warfare agents (CWA), i.e., sulfur mustard, lewisite and nerve agents, is presented. Such methods can be applied for various purposes, e.g., diagnosis and dosimetry of exposure of

  17. Recent canadian experience in chemical warfare agent destruction. An overview

    Energy Technology Data Exchange (ETDEWEB)

    McAndless, J.M.

    1995-09-01

    A Canadian chemical warfare agent destruction project (Swiftsure) was recently completed in which stockpiles of aged mustard, lewisite, nerve agents and contaminated scrap metal were incinerated or chemically neutralized in a safe, environmentally-responsible manner. The project scope, destruction technologies, environmental monitoring and public consultation programs are described.

  18. Overview of research in radiation biology and protective measures in the Manhattan Project during the war years, 1942-1946

    International Nuclear Information System (INIS)

    Friedell, H.L.

    The objecitve was to present a cohesive view of the general biological research program associated with the Manhattan Project. The material is arrangd in chronological order. Each of the major research sites is identified and the general nature of their research program indicated. A section is devoted to the question of the various radiation limits which were used in the operational approach to hazard controls

  19. Regulated programmed lysis of recombinant Salmonella in host tissues to release protective antigens and confer biological containment

    OpenAIRE

    Kong, Wei; Wanda, Soo-Young; Zhang, Xin; Bollen, Wendy; Tinge, Steven A.; Roland, Kenneth L.; Curtiss, Roy

    2008-01-01

    We have devised and constructed a biological containment system designed to cause programmed bacterial cell lysis with no survivors. We have validated this system, using Salmonella enterica serovar Typhimurium vaccines for antigen delivery after colonization of host lymphoid tissues. The system is composed of two parts. The first component is Salmonella typhimurium strain χ8937, with deletions of asdA and arabinose-regulated expression of murA, two genes required for peptidoglycan synthesis a...

  20. Microarrays – new possibilities for detecting biological factors hazardous for humans and animals, and for use in environmental protection

    Directory of Open Access Journals (Sweden)

    Tomasz Mirski

    2015-12-01

    Full Text Available Both the known biological agents that cause infectious diseases, as well as modified (ABF-Advanced Biological Factors or new, emerging agents pose a significant diagnostic problem using previously applied methods, both classical, as well as based on molecular biology methods. The latter, such as PCR and real-time PCR, have significant limitations, both quantitative (low capacity, and qualitative (limited number of targets. The article discusses the results of studies on using the microarray method for the identification of viruses (e.g. Orthopoxvirus group, noroviruses, influenza A and B viruses, rhino- and enteroviruses responsible for the FRI (Febrile Respiratory Illness, European bunyaviruses, and SARS-causing viruses, and bacteria ([i]Mycobacterium spp., Yersinia spp., Campylobacter spp., Streptococcus pneumoniae, Salmonella typhi, Salmonella enterica, Staphylococcus aureus, Neisseria meningitidis, Clostridium difficile , Helicobacter pylori[/i], including multiple antibiotic-resistant strains. The method allows for the serotyping and genotyping of bacteria, and is useful in the diagnosis of genetically modified agents. It allows the testing of thousands of genes in one experiment. In addition to diagnosis, it is applicable for gene expression studies, analysis of the function of genes, microorganisms virulence, and allows the detection of even single mutations. The possibility of its operational application in epidemiological surveillance, and in the detection of disease outbreak agents is demonstrated.

  1. Decontamination of adsorbed chemical warfare agents on activated carbon using hydrogen peroxide solutions.

    Science.gov (United States)

    Osovsky, Ruth; Kaplan, Doron; Nir, Ido; Rotter, Hadar; Elisha, Shmuel; Columbus, Ishay

    2014-09-16

    Mild treatment with hydrogen peroxide solutions (3-30%) efficiently decomposes adsorbed chemical warfare agents (CWAs) on microporous activated carbons used in protective garments and air filters. Better than 95% decomposition of adsorbed sulfur mustard (HD), sarin, and VX was achieved at ambient temperatures within 1-24 h, depending on the H2O2 concentration. HD was oxidized to the nontoxic HD-sulfoxide. The nerve agents were perhydrolyzed to the respective nontoxic methylphosphonic acids. The relative rapidity of the oxidation and perhydrolysis under these conditions is attributed to the microenvironment of the micropores. Apparently, the reactions are favored due to basic sites on the carbon surface. Our findings suggest a potential environmentally friendly route for decontamination of adsorbed CWAs, using H2O2 without the need of cosolvents or activators.

  2. Simulation to aid in interpreting biological relevance and setting of population-level protection goals for risk assessment of pesticides.

    Science.gov (United States)

    Topping, Christopher John; Luttik, Robert

    2017-10-01

    Specific protection goals (SPGs) comprise an explicit expression of the environmental components that need protection and the maximum impacts that can be tolerated. SPGs are set by risk managers and are typically based on protecting populations or functions. However, the measurable endpoints available to risk managers, at least for vertebrates, are typically laboratory tests. We demonstrate, using the example of eggshell thinning in skylarks, how simulation can be used to place laboratory endpoints in context of population-level effects as an aid to setting the SPGs. We develop explanatory scenarios investigating the impact of different assumptions of eggshell thinning on skylark population size, density and distribution in 10 Danish landscapes, chosen to represent the range of typical Danish agricultural conditions. Landscape and timing of application of the pesticide were found to be the most critical factors to consider in the impact assessment. Consequently, a regulatory scenario of monoculture spring barley with an early spray treatment eliciting the eggshell thinning effect was applied using concentrations eliciting effects of zero to 100% in steps of 5%. Setting the SPGs requires balancing scientific, social and political realities. However, the provision of clear and detailed options such as those from comprehensive simulation results can inform the decision process by improving transparency and by putting the more abstract testing data into the context of real-world impacts. Copyright © 2017 Elsevier Inc. All rights reserved.

  3. Radiation protection

    International Nuclear Information System (INIS)

    Ures Pantazi, M.

    1994-01-01

    This work define procedures and controls about ionizing radiations. Between some definitions it found the following topics: radiation dose, risk, biological effects, international radioprotection bodies, workers exposure, accidental exposure, emergencies and radiation protection

  4. Activities of Project 'Cooperation and development with Latin America and Iberian in Biological Dosimetry of Iberian Group of Radiation Protection Societies

    International Nuclear Information System (INIS)

    Nasazzi, Nora B.; Taja, Maria R.; Giorgio, Marina di; Garcia Lima, Omar; Lamadrid, Ana I.; Olivares, Pilar; Moreno, Mercedes; Prieto, Maria J.; Espinosa, Marco

    2001-01-01

    In 1996 the GRIAPRA Group (Latin American and Iberian Group of Radiation Protection Societies) was established with the participation of Argentina, Brazil, Cuba, Mexico, Peru, Portugal and Spain. In 1998 began the biennial Collaborative Working Project 'Cooperation and Development with Latin America in Biological Dosimetry', partially supported by the Extremadura Government, Spain, initially involving five countries: Argentina, Cuba, Peru, Portugal and Spain. The general aim of the project is to create an Latin American and Iberian Biological Dosimetry Laboratories Coordinated Group in order to: give mutual cooperation and to other countries if required, in the case of radiological accident; contribute to enhance the technical capabilities of the participant laboratories; promote the installment of laboratories on this field in countries that does not have it yet through the training of human resources and providing the necessary equipment and, finally, perform jointly research activities in biological dosimetry. The activities designed in order to accomplish the project specific aims for the 1998-2000 period have been achieved. Description and results are presented. (author)

  5. Review of studies validating the protective efficacy of a new technology designed to compensate adverse biological effects caused by vdu and GSM cell phone radiation

    International Nuclear Information System (INIS)

    Youbicier-Simo, B.J.; Messagier, R.; Fillion-Robin, M

    2001-01-01

    A total of 13 studies were initiated and coordinated by Technolab Research Center in 6 laboratories from 3 countries (France, UK, Japan). These studies were aimed at: 1) investigating potential adverse biological effects associated with exposure to non ionizing radiation emitted by two types of communication devices, video display units and cell phones; 2) assessing the efficacy of a compensation magnetic oscillating technology designed to protect from non ionizing radiation. Five types of biological systems including chicken embryos, young chickens, healthy mice, mice suffering from cancer and humans were used. A set of 10 biological parameters were assessed, including embryonic mortality, hormones, antibodies, haematological parameters, stress, mood, ocular damage, neurogenesis, micronuclei formation and intracellular calcium. Overall endpoints were affected by irradiation, in terms of increased embryonic mortality, immune depression, depletion of hormones crucial for the regulation of the immune system, changes in haematological parameters, increased stress, mood alteration, induction of ophthalmologic disorders, inhibition of the neurogenesis in brain areas associated with memory processes, induction of symptoms of cell dysfunction, apoptosis or cancer, and disruption of trans-membrane fluxes of calcium. On the other hand, the compensation magnetic oscillation technology tested allowed significant correction of altered physiological parameters, as well as improvement or disappearance of observed pathological symptoms (author)

  6. History of the Chemical Warfare Service in World War II. Biological Warfare Research in the United States, Volume 2

    Science.gov (United States)

    1947-11-01

    regarded as a pos- itive test. No individual, however, with a known history of brucell - osis or skin sensitivity was given either Brucellergen...investigation made of the organism and toxin. Brucell - osis caused the greatest tiaie loss per case, averaging 177 days; glanders was next with 121 days...Eeningopneumonitis viruses, brucel - losis, tularemia, end melioido3is. Studies were also made using this type chamber on the employment of a dye as a tracer in

  7. Defending Our Satellites: The Need for Electronic Warfare Education and Training

    Science.gov (United States)

    2015-12-01

    intercept Allied bombers attacking at night.9 As a result of the electronic warfare advantage that systems like Window and Airborne Cigar be- stowed...74 | Air & Space Power Journal Defending Our Satellites The Need for Electronic Warfare Education and Training Lt Col E. Lincoln Bonner, USAF...expanding education and training in the use of electronic warfare to defend US satellites and improve their survivability. The following discussion

  8. Regulated programmed lysis of recombinant Salmonella in host tissues to release protective antigens and confer biological containment.

    Science.gov (United States)

    Kong, Wei; Wanda, Soo-Young; Zhang, Xin; Bollen, Wendy; Tinge, Steven A; Roland, Kenneth L; Curtiss, Roy

    2008-07-08

    We have devised and constructed a biological containment system designed to cause programmed bacterial cell lysis with no survivors. We have validated this system, using Salmonella enterica serovar Typhimurium vaccines for antigen delivery after colonization of host lymphoid tissues. The system is composed of two parts. The first component is Salmonella typhimurium strain chi8937, with deletions of asdA and arabinose-regulated expression of murA, two genes required for peptidoglycan synthesis and additional mutations to enhance complete lysis and antigen delivery. The second component is plasmid pYA3681, which encodes arabinose-regulated murA and asdA expression and C2-regulated synthesis of antisense asdA and murA mRNA transcribed from the P22 P(R) promoter. An arabinose-regulated c2 gene is present in the chromosome. chi8937(pYA3681) exhibits arabinose-dependent growth. Upon invasion of host tissues, an arabinose-free environment, transcription of asdA, murA, and c2 ceases, and concentrations of their gene products decrease because of cell division. The drop in C2 concentration results in activation of P(R), driving synthesis of antisense mRNA to block translation of any residual asdA and murA mRNA. A highly antigenic alpha-helical domain of Streptococcus pneumoniae Rx1 PspA was cloned into pYA3681, resulting in pYA3685 to test antigen delivery. Mice orally immunized with chi8937(pYA3685) developed antibody responses to PspA and Salmonella outer membrane proteins. No viable vaccine strain cells were detected in host tissues after 21 days. This system has potential applications with other Gram-negative bacteria in which biological containment would be desirable.

  9. New calculation of derived limits for the 1960 radiation protection guides reflecting updated models for dosimetry and biological transport

    International Nuclear Information System (INIS)

    Eckerman, K.F.; Watson, S.B.; Nelson, C.B.; Nelson, D.R.; Richardson, A.C.B.; Sullivan, R.E.

    1984-12-01

    This report presents revised values for the radioactivity concentration guides (RCGs), based on the 1960 primary radiation protection guides (RPGs) for occupational exposure (FRC 1960) and for underground uranium miners (EPA 1971a) using the updated dosimetric models developed to prepare ICRP Publication 30. Unlike the derived quantities presented in Publication 30, which are based on limitation of the weighted sum of doses to all irradiated tissues, these RCGs are based on the ''critical organ'' approach of the 1960 guidance, which was a single limit for the most critically irradiated organ or tissue. This report provides revised guides for the 1960 Federal guidance which are consistent with current dosimetric relationships. 2 figs., 4 tabs

  10. Cultural Competence and the Operational Commander: Moving Beyond Cultural Awareness into Culture-Centric Warfare

    National Research Council Canada - National Science Library

    Karcanes, James A

    2007-01-01

    .... Understanding the different levels of cultural awareness -- cultural consideration, cultural understanding, and cultural competence -- will help usher in a new focus on culture-centric warfare...

  11. Ending the Debate: Unconventional Warfare, Foreign Internal Defense, and Why Words Matter

    National Research Council Canada - National Science Library

    Jones, D

    2006-01-01

    There is an ongoing debate within the Special Forces community whether unconventional warfare and foreign internal defense are applicable in the contemporary and future Special Operations environments...

  12. Mass Spectrometric Determination of Chemical Warfare Agents in Indoor Sample Media Typically Collected During Forensic Investigations

    National Research Council Canada - National Science Library

    D'Agostino, P. A; Hancock, J. R; Chenier, C. L

    2005-01-01

    .... DRDC Suffield, in collaboration with the Royal Canadian Mounted Police, identified a need for analytical methods for chemical warfare agent identification in media, including flooring, wall surfaces...

  13. Redefining Hybrid Warfare: Russia's Non-linear War against the West

    Directory of Open Access Journals (Sweden)

    Tad Schnaufer

    2017-03-01

    Full Text Available The term hybrid warfare fails to properly describe Russian operations in Ukraine and elsewhere. Russia has undertaken unconventional techniques to build its influence and test the boundaries of a shaken international system. Notably, Russia’s actions in Ukraine display an evolved style of warfare that goes beyond its initial label of hybrid warfare. The term non-linear war (NLW will be defined in this article to encompass Russia’s actions and allow policymakers the correct framework to discuss and respond to Russia. NLW plays to the advantage of countries like Russia and constitute the future of warfare.

  14. Decontamination and Detoxification of Toxic Chemical Warfare Agents Using Polyurethane Sponges

    National Research Council Canada - National Science Library

    Gordon, Richard K; Gunduz, Alper T; Askins, LaTawnya Y; Strating, Simon J; Doctor, Bhupendra P; Clarkson, Edward D; Mitchelree, Larry W; Lukey, Brian; Railer, Roy; Schulz, Susan

    2003-01-01

    .... Another serious problem that may be encountered while caring for personnel contaminated with organophosphorus chemical warfare nerve agents is the possibility that there will be cross-contamination...

  15. Guerra e desenvolvimento biológico: o caso da biotecnologia e da genômica na segunda metade do século XX Warfare and biological development: the case of biotechnology and genomics during the second half of the 20th Century

    Directory of Open Access Journals (Sweden)

    Maria Eneida de Almeida

    2006-09-01

    Full Text Available Desde a década de 1980, a Biotecnologia vem assumindo um papel cada vez mais importante dentro do planejamento estratégico das Grandes Potências, como elemento central para um novo tipo de arma ofensiva de destruição em massa e como paradigma para o planejamento de defesa e proteção de suas populações nacionais. Para defender esta tese, nosso estudo se orientou exatamente na história do deslocamento da Biologia para o centro do planejamento de defesa americano. Nosso objetivo foi investigar a existência de uma estreita relação entre o Desenvolvimento Biotecnológico, da ciência Genômica em particular, e a questão da guerra. Nossa hipótese é que a Biotecnologia se afirmou no campo da guerra, quando foram atingidos um ponto de condensação de fatos políticos e uma confluência de possibilidades biotécnicas que estimularam acentuadamente o interesse político-militar. A metodologia para a investigação desta conexão deu-se por dois caminhos: uma análise teórica, onde encontramos as origens e o mecanismo da Big Science desde a II Guerra Mundial, quando a Física assumiu o eixo central da ciência de ponta na era atômica, e desde a década de 1980, quando a Biologia passou a ocupar um lugar central; e uma análise historiográfica, acompanhando duas trajetórias convergentes que, para a nossa tese, formam o nervo central do Desenvolvimento Biotecnológico, da Guerra Biológica e do Projeto Genoma Humano.Since the 1980's, biotechnology has played an increasingly predominant role in the strategic planning of the super-powers, as the central element of a new type of mass destruction weapon as well as a model for defense planning and protection of their national populations. This study aims to demonstrate the path taken by Biology towards the core of American defense planning and also to investigate the close relationship between biotechnological development, in particular that of Genome Science and war. The specific hypothesis

  16. Stuxnet and Cyber-Warfare (2/2)

    CERN Multimedia

    CERN. Geneva

    2016-01-01

    The first part of the lecture is devoted to the description of the Stuxnet worm, the first cyber-weapon whose existence has been made public, discovered in 2010 and targeting a specific industrial control system; the worm is responsible for the damaging of many centrifuges at an uranium enrichment facility, with the goal of sabotaging Iran's nuclear program. In the second part, the main features of cyber-warfare in conflict and pre-conflict activities will be discussed and compared to the conventional warfare domains, with also a general view at the international political debate on this topic.   Check the http://pugwash.org web site, an organisation that seeks a world free of nuclear weapons and other weapons of mass destruction. The lecturer invites comments via email to Gian.Piero.Siroli@cern.ch NB! All Academic Training lectures are recorded and are publicly available. There is no live webcast.

  17. Stuxnet and Cyber-Warfare (1/2)

    CERN Multimedia

    CERN. Geneva

    2016-01-01

    The first part of the lecture is devoted to the description of the Stuxnet worm, the first cyber-weapon whose existence has been made public, discovered in 2010 and targeting a specific industrial control system; the worm is responsible for the damaging of many centrifuges at an uranium enrichment facility, with the goal of sabotaging Iran's nuclear program. In the second part, the main features of cyber-warfare in conflict and pre-conflict activities will be discussed and compared to the conventional warfare domains, with also a general view at the international political debate on this topic. Check the http://pugwash.org web site, an organisation that seeks a world free of nuclear weapons and other weapons of mass destruction.   NB! All Academic Training lectures are recorded and are publicly available. There is no live webcast.

  18. Identification of chemical warfare agent with radiological measurements

    International Nuclear Information System (INIS)

    Liu Boxue; Li Yun; Ai Xianyun

    2000-01-01

    There are three non-destructive radiological methods for identification of warfare agents and TNT. Their principles and problems related were discussed. Portable isotopic neutron spectroscopy is based on the assay of key elemental composition (such as Cl, P, H, As, S, N) in chemical agents by neutron induced prompt gamma ray analysis. Hydrogen concentration measurement by means of using thermal neutron can be employed to identify chemical warfare agents and TNT that contains different hydrogen fraction. The calibration curves of thermal neutron count rate against hydrogen concentration were measured. X ray imagination system can be used to determine the internal structure of chemical bombs, there by to identify them. The radiological methods are very useful for identification of old chemical weapons abandoned by Japan Army during World War 2

  19. Progress and Challenges of Protecting North American Ash Trees from the Emerald Ash Borer Using Biological Control

    Directory of Open Access Journals (Sweden)

    Jian J. Duan

    2018-03-01

    Full Text Available After emerald ash borer (EAB, Agrilus planipennis Fairmaire, was discovered in the United States, a classical biological control program was initiated against this destructive pest of ash trees (Fraxinus spp.. This biocontrol program began in 2007 after federal regulatory agencies and the state of Michigan approved release of three EAB parasitoid species from China: Tetrastichus planipennisi Yang (Eulophidae, Spathius agrili Yang (Braconidae, and Oobius agrili Zhang and Huang (Encyrtidae. A fourth EAB parasitoid, Spathius galinae Belokobylskij (Braconidae from Russia, was approved for release in 2015. We review the rationale and ecological premises of the EAB biocontrol program, and then report on progress in North American ash recovery in southern Michigan, where the parasitoids were first released. We also identify challenges to conserving native Fraxinus using biocontrol in the aftermath of the EAB invasion, and provide suggestions for program improvements as EAB spreads throughout North America. We conclude that more work is needed to: (1 evaluate the establishment and impact of biocontrol agents in different climate zones; (2 determine the combined effect of EAB biocontrol and host plant resistance or tolerance on the regeneration of North American ash species; and (3 expand foreign exploration for EAB natural enemies throughout Asia.

  20. Just War and Postmodern Warfare: A German Case Study

    Science.gov (United States)

    2015-04-01

    warfare construct, Germany is shaping a military concept based on recent conflicts and unfettered by biases of conventional strategies, organizations...remain sovereign while subconsciously evolving toward liberal democratic ideas. In respecting each country’s political sensitivities, Germany’s...before exhausting all diplomatic, economic and information instruments. Whereas the term AU/ACSC/PINSON/AY15 13 “interests” may bias the United

  1. Nodes and Codes: The Reality of Cyber Warfare

    Science.gov (United States)

    2012-05-17

    respectively. The avionics in Boeing’s 787 Dreamliner require approximately 6.5 million lines of code while the current S-Class Mercedes Benz requires over 20...leaders (demonstrated through outdated policy, theory, and doctrine) and the reality of warfare in 1914 (dictated by innovation, technology , and...or the guidelines to military action codified in doctrine? How are states using the latest technological innovations as violent instruments of

  2. Attacking the infrastructure: exploring potential uses of offensive information warfare

    OpenAIRE

    Elam, Donald Emmett.

    1996-01-01

    The world has entered the Third Wave; it has entered the Information Age. One of the fundamentals of this paradigm shift is the fact that information is power. The side that controls information more effectively will be victorious. Thus, countries and militaries must change their mentality in order to survive. A new form of conflict, Information Warfare, has been born. This new discipline is large, dynamic, and complex. The need exists for education among military officers and other concerned...

  3. Built to Outlast: Operational Approaches to Hybrid Warfare

    Science.gov (United States)

    2012-05-17

    29Robert T. Ames, Sun Tzu: The Art of War (New York: Ballantine Books, 1993), 78-80; Mao Tse -Tung, On Guerrilla Warfare, trans. Samuel B. Griffith...Chicago: University of Illinois Press, 1961), 25, 42.The works of Sun Tzu and Mao Tse -Tung both illustrate aspects of this concept. In a work...toreador’s cape, not the toreador himself. - Norman B. Hannah, The Key to Failure: Laos and the Vietnam War114 Against the backdrop of the Cold

  4. Numerical simulation of RCS for carrier electronic warfare airplanes

    OpenAIRE

    Yue Kuizhi; Liu Wenlin; Li Guanxiong; Ji Jinzu; Yu Dazhao

    2015-01-01

    This paper studies the radar cross section (RCS) of carrier electronic warfare airplanes. Under the typical naval operations section, the mathematical model of the radar wave’s pitch angle incidence range analysis is established. Based on the CATIA software, considering dynamic deflections of duck wing leading edge flaps, flaperons, horizontal tail, and rudder, as well as aircraft with air-to-air missile, anti-radiation missile, electronic jamming pod, and other weapons, the 3D models of carr...

  5. Annihilation Prediction for Lanchester-Type Models of Modern Warfare

    OpenAIRE

    Brown, G.G.; Taylor, J.

    1983-01-01

    Operations Research, 31, p.752. This paper introduces important new functions for analytic solution of Launch-ester-type equations of modern warfare for combat between two homogeneous forces modeled by power attrtition-rate coefficients with "no offset". Tabulations of these Lanchester-Clifford-Schlatii (or LCS) functions allow one to study this particular variable-coefficient model almost as easily and thoroughly as Lanchester's classic constant-coefficient one. LCS functions allow one ...

  6. Inside the Wire: American Security and Cyber Warfare

    Science.gov (United States)

    2017-03-01

    Roberts, Kerry V. " SUN TZU and The Art of Cyber Warfare." Journal of Counterterrorism & Homeland Security International 19, no. 1(Spring 2013): 12-4...12. REPORT TYPE 3. DATES COVERED (From - To) 01-03-2017 Bibliography 4. TITLE AND SUBTITLE Sa. CONTRACT NUMBER Inside the Wire: American Security...MCDERMOTT LIBRARY U.S. AIR FORCE ACADEMY 11. SPONSOR/MONITOR’S REPORT USAF ACADEMY CO 80840-6214 NUMBER(S) Special Bibliography Series # 119 12

  7. Hungarys Alternative to Counter Hybrid Warfare - Small States Weaponized Citizenry

    Science.gov (United States)

    2017-06-09

    said “Resilience as a terminological and operational factor, will become the newest ‘ brand ’ and communication name for the Alliance.”70 He also...audiences to influence their emotions , motives, objective reasoning, and ultimately the behavior of foreign governments, organizations, groups, and...so-called influence warfare. His study pinpointed the importance of emotion over rational facts in messages. Second, Edward Lucas and Ben Nimmo on

  8. Recent Advances in Decontamination of Chemical Warfare Agents

    OpenAIRE

    Abdul Wadood Khan; Sabna Kotta; Shahid Husain Ansari; Javed Ali; Rakesh Kumar Sharma

    2013-01-01

    The recent turmoil and volatile situation in many countries and the increased risk of terrorist activities have raised alarm bells for the field of defense against toxic chemical/materials. These situations poses threats to society as terrorists can take advantage of such situations to strike and cause public mayhem. A number of chemicals have the potential of being used as chemical warfare (CW) agents. CW agents could immediately kill or incapacitate the affected individuals even when they a...

  9. Cyber warfare:terms, issues, laws and controversies

    OpenAIRE

    Seviş, Kamile Nur; Şeker, Ensar

    2016-01-01

    Recent years have shown us the importance of cybersecurity. Especially, when the matter is national security, it is even more essential and crucial. Increasing cyber attacks, especially between countries in governmental level, created a new term cyber warfare. Creating some rules and regulations for this kind of war is necessary therefore international justice systems are working on it continuously. In this paper, we mentioned fundamental terms of cyber...

  10. Littoral Combat Ship Open Ocean Anti-Submarine Warfare

    Science.gov (United States)

    2014-06-01

    maintain stealth and its defense in order to properly conduct an attack on a surface vessel (Sternhell and Thorndike 2014, 102). This statement...its target, the surface combatants can counter by increasing their speed (Sternhell and Thorndike 2014). While the maximum speed of the current...120316_PS.pdf Sternhell, Charles M, and Alan M Thorndike . 2014. “Antisubmarine Warfare in World War II.” CNA Analysis & Solutions. Accessed April 14, 2014

  11. Russian and Chinese Information Warfare: Theory and Practice

    Science.gov (United States)

    2004-06-01

    Integral neurolinguistic programming •Placing essential programs into the conscious or sub- conscious mind •Subconscious suggestions that modify human...Generators of special rays •Optical systems • Neurolinguistic programming •Computer psychotechnology •The mass media •Audiovisual effects •Special effects...Information Warfare: Theory and Practice 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e

  12. Marine protected area restricts demographic connectivity: Dissimilarity in a marine environment can function as a biological barrier.

    Science.gov (United States)

    Sato, Masaaki; Honda, Kentaro; Uy, Wilfredo H; Baslot, Darwin I; Genovia, Tom G; Nakamura, Yohei; Bernardo, Lawrence Patrick C; Kurokochi, Hiroyuki; Pantallano, Allyn Duvin S; Lian, Chunlan; Nadaoka, Kazuo; Nakaoka, Masahiro

    2017-10-01

    The establishment of marine protected areas (MPAs) can often lead to environmental differences between MPAs and fishing zones. To determine the effects on marine dispersal of environmental dissimilarity between an MPA and fishing zone, we examined the abundance and recruitment patterns of two anemonefishes ( Amphiprion frenatus and A. perideraion ) that inhabit sea anemones in different management zones (i.e., an MPA and two fishing zones) by performing a field survey and a genetic parentage analysis. We found lower levels of abundance per anemone in the MPA compared to the fishing zones for both species ( n  = 1,525 anemones, p  = .032). The parentage analysis also showed that lower numbers of fishes were recruited from the fishing zones and outside of the study area into each anemone in the MPA than into each anemone in the fishing zones ( n  = 1,525 anemones, p  fishing zones ( n  = 384 females, p  = .516). Because the ocean currents around the study site were unlikely to cause a lower settlement intensity of larvae in the MPA, the ocean circulation was not considered crucial to the observed abundance and recruitment patterns. Instead, stronger top-down control and/or a lower density of host anemones in the MPA were potential factors for such patterns. Our results highlight the importance of dissimilarity in a marine environment as a factor that affects connectivity.

  13. Theoretical insights into the photo-protective mechanisms of natural biological sunscreens: building blocks of eumelanin and pheomelanin.

    Science.gov (United States)

    Marchetti, Barbara; Karsili, Tolga N V

    2016-02-07

    Eumelanin (EM) and pheomelanin (PM) are ubiquitous in mammalian skin and hair--protecting against harmful radiation from the sun. Their primary roles are to absorb solar radiation and efficiently dissipate the excess excited state energy in the form of heat without detriment to the polymeric structure. EU and PM exist as polymeric chains consisting of exotic arrangements of functionalised heteroaromatic molecules. Here we have used state-of-the-art electronic structure calculations and on-the-fly surface hopping molecular dynamics simulations to study the intrinsic deactivation paths of various building blocks of EU and PM. Ultrafast excited state decay, via electron-driven proton transfer (in EU and PM) and proton-transfer coupled ring-opening (in PM) reactions, have been identified to proceed along hitherto unknown charge-separated states in EU and PM oligomers. These results shed light on the possible relaxation pathways that dominate the photochemistry of natural skin melanins. Extrapolation of such findings could provide a gateway into engineering more effective molecular constituents in commercial sunscreens--with reduced phototoxicity.

  14. Special Forces and the Art of Influence: A Grassroots Approach to Psychological Operations in an Unconventional Warfare Environment

    National Research Council Canada - National Science Library

    Thomas, II, Joel W

    2006-01-01

    This thesis researches the intricacies of the art of influence in an unconventional warfare environment to develop a model of influence that can be utilized by Special Forces conducting unconventional warfare...

  15. Chemical warfare agents identification by thermal neutron detection

    International Nuclear Information System (INIS)

    Liu Boxue; Ai Xianyun; Tan Daoyuan; Zhang Dianqin

    2000-01-01

    The hydrogen concentration determination by thermal neutron detection is a non-destructive, fast and effective method to identify chemical warfare agents and TNT that contain different hydrogen fraction. When an isotropic neutron source is used to irradiate chemical ammunition, hydrogen atoms of the agent inside shell act as a moderator and slow down neutrons. The number of induced thermal neutrons depends mainly upon hydrogen content of the agent. Therefore measurement of thermal neutron influence can be used to determine hydrogen atom concentration, thereby to determine the chemical warfare agents. Under a certain geometry three calibration curves of count rate against hydrogen concentration were measured. According to the calibration curves, response of a chemical agent or TNT could be calculated. Differences of count rate among chemical agents and TNT for each kind of shells is greater than five times of standard deviations of count rate for any agent, so chemical agents or TNT could be identified correctly. Meanwhile, blast tube or liquid level of chemical warfare agent could affect the response of thermal neutron count rate, and thereby the result of identification. (author)

  16. Quality of Life in Iranian Chemical Warfare Veteran's.

    Science.gov (United States)

    Ebadi, Abbas; Moradian, Tayeb; Mollahadi, Mohsen; Saeed, Yaser; Refahi, Ali Akbar

    2014-05-01

    Mustard gas has different effects on different body systems such as respiratory tract, blood, gastrointestinal, skin, eye, endocrine and peripheral nervous system. The purpose of this study was to determine the quality of life in chemical warfare veterans due to sulfur mustard exposure. In a cross-sectional and analytic study, 242 patients who had a chemical injury during the Iran-Iraq war (1980-1983) and their lung damage was proven were investigated in our study. The quality of life was measured in these patients using an extensively validated Iranian version of SF-36. The mean age of veterans was 44.12 ± 4.9 ranging from 22 to 62 years. Our results showed that chemical warfare had a decreased quality of life in all subscales of the SF-36. The lowest scores in SF-36 subscales were related to role physical and general health. The data also showed a significant relationship between the number of organs involved and the quality of life in these patients (P chemical warfare survivors suffering from late complications have a low health related quality of life.

  17. Naval electronic warfare simulation for effectiveness assessment and softkill programmability facility

    Science.gov (United States)

    Lançon, F.

    2011-06-01

    The Anti-ship Missile (ASM) threat to be faced by ships will become more diverse and difficult. Intelligence, rules of engagement constraints, fast reaction-time for effective softkill solution require specific tools to design Electronic Warfare (EW) systems and to integrate it onboard ship. SAGEM Company provides decoy launcher system [1] and its associated Naval Electronic Warfare Simulation tool (NEWS) to permit softkill effectiveness analysis for anti-ship missile defence. NEWS tool generates virtual environment for missile-ship engagement and counter-measure simulator over a wide spectrum: RF, IR, EO. It integrates EW Command & Control (EWC2) process which is implemented in decoy launcher system and performs Monte-Carlo batch processing to evaluate softkill effectiveness in different engagement situations. NEWS is designed to allow immediate EWC2 process integration from simulation to real decoy launcher system. By design, it allows the final operator to be able to program, test and integrate its own EWC2 module and EW library onboard, so intelligence of each user is protected and evolution of threat can be taken into account through EW library update. The objectives of NEWS tool are also to define a methodology for trial definition and trial data reduction. Growth potential would permit to design new concept for EWC2 programmability and real time effectiveness estimation in EW system. This tool can also be used for operator training purpose. This paper presents the architecture design, the softkill programmability facility concept and the flexibility for onboard integration on ship. The concept of this operationally focused simulation, which is to use only one tool for design, development, trial validation and operational use, will be demonstrated.

  18. Chemically-functionalized microcantilevers for detection of chemical, biological and explosive material

    Science.gov (United States)

    Pinnaduwage, Lal A [Knoxville, TN; Thundat, Thomas G [Knoxville, TN; Brown, Gilbert M [Knoxville, TN; Hawk, John Eric [Olive Branch, MS; Boiadjiev, Vassil I [Knoxville, TN

    2007-04-24

    A chemically functionalized cantilever system has a cantilever coated on one side thereof with a reagent or biological species which binds to an analyte. The system is of particular value when the analyte is a toxic chemical biological warfare agent or an explosive.

  19. 78 FR 55326 - Determinations Regarding Use of Chemical Weapons in Syria Under the Chemical and Biological...

    Science.gov (United States)

    2013-09-10

    ... DEPARTMENT OF STATE [Public Notice 8460] Determinations Regarding Use of Chemical Weapons in Syria Under the Chemical and Biological Weapons Control and Warfare Elimination Act of 1991 AGENCY: Bureau of... Government has determined on August 2, pursuant to Section 306(a) of the Chemical and Biological Weapons...

  20. Variations in grain lipophilic phytochemicals, proteins and resistance to Fusarium spp. growth during grain storage as affected by biological plant protection with Aureobasidium pullulans (de Bary).

    Science.gov (United States)

    Wachowska, Urszula; Tańska, Małgorzata; Konopka, Iwona

    2016-06-16

    Modern agriculture relies on an integrated approach, where chemical treatment is reduced to a minimum and replaced by biological control that involves the use of active microorganisms. The effect of the antagonistic yeast-like fungus Aureobasidium pullulans on proteins and bioactive compounds (alkylresorcinols, sterols, tocols and carotenoids) in winter wheat grain and on the colonization of wheat kernels by fungal microbiota, mainly Fusarium spp. pathogens, was investigated. Biological treatment contributed to a slight increase contents of tocols, alkylresorcinols and sterols in grain. At the same time, the variation of wheat grain proteins was low and not significant. Application of A. pullulans enhanced the natural yeast colonization after six months of grain storage and inhibited growth of F. culmorum pathogens penetrating wheat kernel. This study demonstrated that an integrated approach of wheat grain protection with the use of the yeast-like fungus A. pullulans reduced kernel colonization by Fusarium spp. pathogens and increased the content of nutritionally beneficial phytochemicals in wheat grain without a loss of gluten proteins responsible for baking value. Copyright © 2016. Published by Elsevier B.V.

  1. Are Fish and Standardized FETAX Assays Protective Enough for Amphibians? A Case Study on Xenopus laevis Larvae Assay with Biologically Active Substances Present in Livestock Wastes

    Directory of Open Access Journals (Sweden)

    Federica Martini

    2012-01-01

    Full Text Available Biologically active substances could reach the aquatic compartment when livestock wastes are considered for recycling. Recently, the standardized FETAX assay has been questioned, and some researchers have considered that the risk assessment performed on fish could not be protective enough to cover amphibians. In the present study a Xenopus laevis acute assay was developed in order to compare the sensitivity of larvae relative to fish or FETAX assays; veterinary medicines (ivermectin, oxytetracycline, tetracycline, sulfamethoxazole, and trimethoprim and essential metals (zinc, copper, manganese, and selenium that may be found in livestock wastes were used for the larvae exposure. Lethal (LC50 and sublethal effects were estimated. Available data in both, fish and FETAX studies, were in general more protective than values found out in the current study, but not in all cases. Moreover, the presence of nonlethal effects, caused by ivermectin, zinc, and copper, suggested that several physiological mechanisms could be affected. Thus, this kind of effects should be deeply investigated. The results obtained in the present study could expand the information about micropollutants from livestock wastes on amphibians.

  2. Global view on the radiological protection of patients: Position paper by the World Federation of Nuclear Medicine and Biology

    International Nuclear Information System (INIS)

    Amaral, H.

    2001-01-01

    The World Federation of Nuclear Medicine and Biology (WFNMB) is an organization with 60 member countries that are represented by their national nuclear medicine societies and whose main aim is to promote the correct use of this form of medical specialization. Medical research must now comply with strict bioethics criteria that are applied almost universally. Factors such as social value, scientific validity, the risk/benefit ratio and respect for people participating in research are now indispensable in the design of any scientific project. One of the great advances in medicine and medical research has been the acceptance that obtaining the informed consent of people participating in the research is an essential requirement. This also means that we have to make sure that the individuals understand the aim of the study and are aware of its risks and potential benefits as well as the existence of possible alternatives. We are thus obliged to respect their free-dom of choice to participate in, or subject themselves to, a study on an entirely voluntary basis, and their complete freedom to leave a study if they so desire. I would like to take up one final point that relates to the rational use of resources. Until quite recently, it was thought that any lawfully available technological resource could be used, a view that was especially true in relation to medicine. Nowadays, however, there is a strong trend towards the view that the use of both diagnostic and therapeutic techniques must be based on scientific evidence of their usefulness. The empirical use of available resources, without some evidence justifying this use and without a favourable cost-benefit ratio, is no longer accepted as good practice. Conferences such as this one are undoubtedly the most serious manner in which we can tackle these problems, and the conclusions and recommendations we reach must be widely disseminated in the community. The medical applications of radiation have the greatest potential

  3. Essential oils as biological alternatives to protect date palm (Phoenix dactylifera L. against Ectomyelois ceratoniae Zeller (Lepidoptera: Pyralidae

    Directory of Open Access Journals (Sweden)

    Ismail Amri

    2014-09-01

    Full Text Available The aims of this research were to determine the chemical composition of the essential oil of three Tunisian plants and to evaluate their biological activity against eggs, larvae, and adult insects of Ectomyelois ceratoniae Zeller. The essential oils extracted from leaves of Thymus capitatus (L. Hoffmanns. & Link, Rosmarinus officinalis L. and needles of Pinus halepensis Mill. were analyzed by gas chromatography-mass spectrometry; 34, 16, and 56 constituents were identified, respectively. The major constituents were (Z-caryophyllene (23.8%, β-myrcene (20.5% and α-pinene (13.3% in P. halepensis oil, carvacrol (66.9%, p-cymene (9.1%, and δ-terpinene (6.2% in T. capitatus oil and 1,8-cineole (47.5%, camphor (14.9%, α-pinene (14.1%, and borneol (13.1% in R. officinalis oil. The insecticidal effects of essential oils on eggs, larvae, and adults of E. ceratoniae were investigated. Ovicidal activity of oils was studied by spray on eggs while larvicidal and adulticidal activities were assessed by fumigation and spray. Number of hatched eggs was verified after 10 d, larva and adult mortalities were observed after 6, 12, and 24 h. Globally, eggs and larvae were the most resistant to the three different oils, needing higher doses to obtain a higher mortality. The spray method was most effective than fumigation. Essential oil extracted from T. capitatus proved to be very toxic towards E. ceratoniae on all three phases at the dose of 20 μL mL-1 (100% inhibition, followed by the oil from R. officinalis (90-100% inhibition, nevertheless, weak activity was obtained with P. halepensis oil (68.3-85% inhibition. Results obtained may suggest that the essential oils of T. capitatus and R. officinalis possess high insecticidal activity and therefore, can be used in biotechnological application as natural preservative in stored dates and could be useful in managing populations of E. ceratoniae in field.

  4. Protection against LPS-induced cartilage inflammation and degradation provided by a biological extract of Mentha spicata

    Directory of Open Access Journals (Sweden)

    Kott Laima S

    2010-05-01

    Full Text Available Abstract Background A variety of mint [Mentha spicata] has been bred which over-expresses Rosmarinic acid (RA by approximately 20-fold. RA has demonstrated significant anti-inflammatory activity in vitro and in small rodents; thus it was hypothesized that this plant would demonstrate significant anti-inflammatory activity in vitro. The objectives of this study were: a to develop an in vitro extraction procedure which mimics digestion and hepatic metabolism, b to compare anti-inflammatory properties of High-Rosmarinic-Acid Mentha spicata (HRAM with wild-type control M. spicata (CM, and c to quantify the relative contributions of RA and three of its hepatic metabolites [ferulic acid (FA, caffeic acid (CA, coumaric acid (CO] to anti-inflammatory activity of HRAM. Methods HRAM and CM were incubated in simulated gastric and intestinal fluid, liver microsomes (from male rat and NADPH. Concentrations of RA, CA, CO, and FA in simulated digest of HRAM (HRAMsim and CM (CMsim were determined (HPLC and compared with concentrations in aqueous extracts of HRAM and CM. Cartilage explants (porcine were cultured with LPS (0 or 3 μg/mL and test article [HRAMsim (0, 8, 40, 80, 240, or 400 μg/mL, or CMsim (0, 1, 5 or 10 mg/mL, or RA (0.640 μg/mL, or CA (0.384 μg/mL, or CO (0.057 μg/mL or FA (0.038 μg/mL] for 96 h. Media samples were analyzed for prostaglandin E2 (PGE2, interleukin 1β (IL-1, glycosaminoglycan (GAG, nitric oxide (NO and cell viability (differential live-dead cell staining. Results RA concentration of HRAMsim and CMsim was 49.3 and 0.4 μg/mL, respectively. CA, FA and CO were identified in HRAMsim but not in aqueous extract of HRAM. HRAMsim (≥ 8 μg/mL inhibited LPS-induced PGE2 and NO; HRAMsim (≥ 80 μg/mL inhibited LPS-induced GAG release. RA inhibited LPS-induced GAG release. No anti-inflammatory or chondroprotective effects of RA metabolites on cartilage explants were identified. Conclusions Our biological extraction procedure produces

  5. Synthetic biology and biosecurity: challenging the "myths".

    OpenAIRE

    Jefferson, C; Lentzos, F; Marris, C

    2014-01-01

    15.10.14 KB. Ok to add published version to spiral, OA paper under cc by Synthetic biology, a field that aims to make biology easier to engineer, is routinely described as leading to an increase in the dual-use threat, i.e., the potential for the same scientific research to be used for peaceful purposes or misused for warfare or terrorism. Fears have been expressed that the de-skilling of biology, combined with online access to the genomic DNA sequences of pathogenic organisms an...

  6. Evaluation of the Modern State of Water Ecosystems and the Issues with Protecting Biological Resources During Development of the Kruzenshternskoye Gas Condensate Field

    Directory of Open Access Journals (Sweden)

    Vladimir Dmitrievich Bogdanov

    2015-09-01

    Full Text Available In the article, the results of the studies of the present state of freshwater ecosystems and their biotic components in the western part of the Yamal Peninsula are presented. Based on the evaluation of the structure of the communities of phytoplankton, zooplankton, benthos and whitefishes, the range of the problems related to the protection of biological resources at the development of the Kruzenshternskoye gas field is defined. Data on species composition and quantitative indicators of hydrobionts of different types of waterbodies and watercourses in the lower reaches of the Mordyyakha and Naduyyakha rivers basins are the basis for environmental monitoring of water objects at development and exploitation of the Kruzenshternskoye gas field. According to the monitoring program, evaluation of the fish fauna state and their food base on the territory of the Kruzenshternskoye gas condensate field (GCF, is present. The zones of rivers deltas are the most important areas of the salmonid and whitefishes valuable fish species feeding at the territory of Kruzenshternskoye GCF. In the cases where complete demolish of waterbodies and watercourses for construction of facilities for GCF does not occur, changes of quantitative and qualitative characteristics of communities of hydrobionts after cease of works are reversible. River ecosystems are restored within a more short period of time in comparison to lacustrine ones. On the basis of conducted comprehensive studies, the proposals for the protection of fisheries resources and monitoring of aquatic ecosystems are reported. Recommendations for reducing the anthropogenic impact on aquatic ecosystems in the development period are presented. The results of the investigation were used in the designing the environmental protection part of the Kruzenshternskoye deposit project. At present, the disturbances in the territory of Kruzenshternskoye deposit of gas does not impact the aquatic ecosystems

  7. Are we missing the boat? Current uses of long-term biological monitoring data in the evaluation and management of marine protected areas.

    Science.gov (United States)

    Addison, P F E; Flander, L B; Cook, C N

    2015-02-01

    Protected area management agencies are increasingly using management effectiveness evaluation (MEE) to better understand, learn from and improve conservation efforts around the globe. Outcome assessment is the final stage of MEE, where conservation outcomes are measured to determine whether management objectives are being achieved. When quantitative monitoring data are available, best-practice examples of outcome assessments demonstrate that data should be assessed against quantitative condition categories. Such assessments enable more transparent and repeatable integration of monitoring data into MEE, which can promote evidence-based management and improve public accountability and reporting. We interviewed key informants from marine protected area (MPA) management agencies to investigate how scientific data sources, especially long-term biological monitoring data, are currently informing conservation management. Our study revealed that even when long-term monitoring results are available, management agencies are not using them for quantitative condition assessment in MEE. Instead, many agencies conduct qualitative condition assessments, where monitoring results are interpreted using expert judgment only. Whilst we found substantial evidence for the use of long-term monitoring data in the evidence-based management of MPAs, MEE is rarely the sole mechanism that facilitates the knowledge transfer of scientific evidence to management action. This suggests that the first goal of MEE (to enable environmental accountability and reporting) is being achieved, but the second and arguably more important goal of facilitating evidence-based management is not. Given that many MEE approaches are in their infancy, recommendations are made to assist management agencies realize the full potential of long-term quantitative monitoring data for protected area evaluation and evidence-based management. Copyright © 2014 Elsevier Ltd. All rights reserved.

  8. Protective Role of Carnitine against the Harmful Biological Effects of Paracetamol and Radiation Exposure in Male Albino Rats

    International Nuclear Information System (INIS)

    Abd El Rahman, N.A.

    2012-01-01

    L-carnitine, a natural component of mammalian tissue, is a necessary factor in the utilization of long-chain fatty acids to produce energy. Furthermore it has been shown to protect cells from per oxidative stress. The objective of the present study was to evaluate the efficacy of L-carnitine on hepatotoxicity and nephrotoxicity induced by paracetamol, γ-radiation, and paracetamol + γ-radiation. Male albino rats were divided into 8 groups. 1-Control group: rats not subject to any treatment, 2-Carnitine group: rats received L-carnitine (0.5 ml/Kg body weight) via intraperitoneal injection during 21 days, 3-Paracetamol group: rats received paracetamol (50 mg/kg body) via intraperi-toneal injection during 21 days, 4- Carnitine + Paracetamol group: rats received L-carnitine in parallel to paracetamol treatment, 5- Radiation groups: rats were whole body gamma irradiated with 7 Gy, 6- Carnitine + Radiation group: rats received L-carnitine for 21 days before whole body gamma irradiation with 7Gy, 7- Paracetamol + Radiation group: rats received paracetamol during 21 days before whole body gamma irradiation, 8- Carnitine + Paracetamol + Radiation group: rats received L-carnitine parallel to paracetamol during 21 days before whole body gamma irradiation.The results demonstrated that rats receiving paracetamol, as well as whole body gamma irradiated rats and rats receiving paracetamol and irradiated showed a significant increase of alanine amino transferase (ALT), aspartate amino transferase (AST), and alkaline phosphatase (ALP) activities, and a significant decrease of gamma-glutamyl transpeptidase (GGT) activity indicating liver injury. A significant increase of urea, creatinine and uric acid levels was recorded also indicating kidney damage. Alteration in liver and kidney functions was accompanied by a significant increase in the content of thiobarbituric acid reactive substances (TBARS) associated with a significant decrease in glutathione (GSH) content and superoxide

  9. Risk, Military Ethics and Irregular Warfare

    Science.gov (United States)

    2011-12-01

    permissible; they are obligatory. Given the state’s moral obligation to protect its citizens, 6 military operations conducted in their defense are prima ... facie obligated, even when conducting those operations exposes combatants to harm. 7 Thus, in what I will refer to as the “traditional view,” by taking...feature of the traditional view. In an article co-written in 2005 with then Major General Amos Yadlin, Kasher remarked: “the duty to minimize casualties

  10. United States Coast Guard Antisubmarine Warfare (ASW) in the Maritime Defense Zone (MDZ) - A Strategic Approach

    Science.gov (United States)

    1989-03-01

    RIC ILE COPY AIR WAR COLLGE REEAC R~pCR UNITED STATES COAST GUARD ANTISUBMARINE WARFARE (ASW) IN THE MARITIME DEFENSE ZONE (MDZ) -A STRATEGIC...going to perform in these MDZs. Those tasks identified so far include: port and coastal physical security & preventive safety, mine warfare

  11. The Utility of Freedom: A Principal-Agent Model for Unconventional Warfare

    Science.gov (United States)

    2011-06-01

    Lanchester Model of Guerrilla Warfare,‖ Operations Research 10, no. 6 (December 1962): 818–827; William A. Niskanen, ―Review: The Economics of Insurgency...http://galenet.galegroup.com/servlet/DDRS?locID=navalps. Deitchman, S. J. ―A Lanchester Model of Guerrilla Warfare.‖ Operations Research 10, no

  12. Understanding the elementary considerations in a network warfare environment: an introductory framework

    CSIR Research Space (South Africa)

    Veerasamy, N

    2008-07-01

    Full Text Available . It seeks to offer a better introductory understanding to the field of network warfare. This paper addresses the requirements for a network warfare capability and will look at the high-level approach, constraints, focus areas, levels, techniques...

  13. Metal organic frameworks for the catalytic detoxification of chemical warfare nerve agents

    Science.gov (United States)

    Hupp, Joseph T.; Farha, Omar K.; Katz, Michael J.; Mondloch, Joseph E.

    2017-04-18

    A method of using a metal organic framework (MOF) comprising a metal ion and an at least bidendate organic ligand to catalytically detoxify chemical warfare nerve agents including exposing the metal-organic-framework (MOF) to the chemical warfare nerve agent and catalytically decomposing the nerve agent with the MOF.

  14. Study on the identification method of chemical warfare agents with spectroscopy of neutron induced γ rays

    International Nuclear Information System (INIS)

    Liu Boxue; Li Yun; Li Xiangbao

    1996-01-01

    The paper briefly describes some non-destructive verification technologies of chemical warfare agents in-site, and some application of neutron induced gamma ray analysis, such as multi-elements analysis of coal, hidden explosive detection and identification of chemical agents. It also describes some problems in developing the portable isotopic neutron spectroscopy for non-destructive evaluation of chemical warfare agents

  15. Antidotes and treatments for chemical warfare/terrorism agents: an evidence-based review.

    Science.gov (United States)

    Rodgers, G C; Condurache, C T

    2010-09-01

    This article reviews the evidence supporting the efficacy of antidotes used or recommended for the potential chemical warfare agents of most concern. Chemical warfare agents considered include cyanide, vesicants, pulmonary irritants such as chlorine and phosgene, and nerve agents. The strength of evidence for most antidotes is weak, highlighting the need for additional research in this area.

  16. Status of dental health in chemical warfare victims: The case of Isfahan, Iran

    Directory of Open Access Journals (Sweden)

    Ahmad Mottaghi

    2012-01-01

    Conclusion: Chemical warfare victims have relatively poor dental/oral health. Chemical injury might cause a dysfunction in saliva secretion, with decrease in saliva secretion increasing the risk for tooth decay and periodontal disorders. Further research is required to find out the exact underlying mechanisms and the factors associated with poor dental/oral health in chemical warfare victims.

  17. 75 FR 6642 - Notice of Proposed Information Collection; Naval Special Warfare Recruiting Directorate

    Science.gov (United States)

    2010-02-10

    ... Information Collection; Naval Special Warfare Recruiting Directorate AGENCY: Department of the Navy, DoD. ACTION: Notice. SUMMARY: The Naval Special Warfare (NSW) Recruiting Directorate announces the submission... any of the following methods: Federal eRulemaking Portal: http://www.regulations.gov . Follow the...

  18. Analysis of the Precursors, Simulants and Degradation Products of Chemical Warfare Agents.

    Science.gov (United States)

    Witkiewicz, Zygfryd; Neffe, Slawomir; Sliwka, Ewa; Quagliano, Javier

    2018-09-03

    Recent advances in analysis of precursors, simulants and degradation products of chemical warfare agents (CWA) are reviewed. Fast and reliable analysis of precursors, simulants and CWA degradation products is extremely important at a time, when more and more terrorist groups and radical non-state organizations use or plan to use chemical weapons to achieve their own psychological, political and military goals. The review covers the open source literature analysis after the time, when the chemical weapons convention had come into force (1997). The authors stated that during last 15 years increased number of laboratories are focused not only on trace analysis of CWA (mostly nerve and blister agents) in environmental and biological samples, but the growing number of research are devoted to instrumental analysis of precursors and degradation products of these substances. The identification of low-level concentration of CWA degradation products is often more important and difficult than the original CWA, because of lower level of concentration and a very large number of compounds present in environmental and biological samples. Many of them are hydrolysis products and are present in samples in the ionic form. For this reason, two or three instrumental methods are used to perform a reliable analysis of these substances.

  19. Translational environmental biology: cell biology informing conservation.

    Science.gov (United States)

    Traylor-Knowles, Nikki; Palumbi, Stephen R

    2014-05-01

    Typically, findings from cell biology have been beneficial for preventing human disease. However, translational applications from cell biology can also be applied to conservation efforts, such as protecting coral reefs. Recent efforts to understand the cell biological mechanisms maintaining coral health such as innate immunity and acclimatization have prompted new developments in conservation. Similar to biomedicine, we urge that future efforts should focus on better frameworks for biomarker development to protect coral reefs. Copyright © 2014 Elsevier Ltd. All rights reserved.

  20. Ultra-Fast Degradation of Chemical Warfare Agents Using MOF-Nanofiber Kebabs.

    Science.gov (United States)

    Zhao, Junjie; Lee, Dennis T; Yaga, Robert W; Hall, Morgan G; Barton, Heather F; Woodward, Ian R; Oldham, Christopher J; Walls, Howard J; Peterson, Gregory W; Parsons, Gregory N

    2016-10-10

    The threat associated with chemical warfare agents (CWAs) motivates the development of new materials to provide enhanced protection with a reduced burden. Metal-organic frame-works (MOFs) have recently been shown as highly effective catalysts for detoxifying CWAs, but challenges still remain for integrating MOFs into functional filter media and/or protective garments. Herein, we report a series of MOF-nanofiber kebab structures for fast degradation of CWAs. We found TiO 2 coatings deposited via atomic layer deposition (ALD) onto polyamide-6 nanofibers enable the formation of conformal Zr-based MOF thin films including UiO-66, UiO-66-NH 2 , and UiO-67. Cross-sectional TEM images show that these MOF crystals nucleate and grow directly on and around the nanofibers, with strong attachment to the substrates. These MOF-functionalized nanofibers exhibit excellent reactivity for detoxifying CWAs. The half-lives of a CWA simulant compound and nerve agent soman (GD) are as short as 7.3 min and 2.3 min, respectively. These results therefore provide the earliest report of MOF-nanofiber textile composites capable of ultra-fast degradation of CWAs. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Radiation protection

    International Nuclear Information System (INIS)

    Koelzer, W.

    1976-01-01

    The lecture is divided into five sections. The introduction deals with the physical and radiological terms, quantities and units. Then the basic principles of radiological protection are discussed. In the third section attention is paid to the biological effects of ionizing radiation. The fourth section deals with the objectives of practical radiological protection. Finally the emergency measures are discussed to be taken in radiation accidents. (HP) [de

  2. Getting the Next War Right: Beyond Population-centric Warfare

    Science.gov (United States)

    2010-06-01

    respectively: Che Guevara and Mao Tse -tung. Che’s foco theory, as we have discussed, advocates mobilizing from the top. The armed challenger chooses an...example, Thomas A. Marks, “Guerrillas in the Mist: Hmong Resistance Continues in Laos ,” Combat and Survival 8, no. 5 (August 1996), 4–11. 12 Theory and...Mao Tse -tung, On Guerrilla Warfare, trans. and ed. Samuel B. Grif!th (Mineola, NY: Dover Publications, 2005). The book is available from a wide

  3. Environmental assessments of sea dumped chemical warfare agents

    DEFF Research Database (Denmark)

    Sanderson, Hans; Fauser, Patrik

    This is a report on the information gathered during work related to sea dumped chemical warfare agents. It mainly reviews the work conducted in relation to the installation of the two Nord Stream gas pipeline from 2008-2012. The focus was on the weight-of-evidence risk assessment of disturbed CWA...... residues in connection with the installation of the pipelines. Novel exposure and toxicity assessments are presented and the risk is assessed. The overall conclusion is that there is a negligible acute added CWA risk towards the fish community from the installation of the pipelines....

  4. Ultraviolet Raman scattering from persistent chemical warfare agents

    Science.gov (United States)

    Kullander, Fredrik; Wästerby, Pär.; Landström, Lars

    2016-05-01

    Laser induced Raman scattering at excitation wavelengths in the middle ultraviolet was examined using a pulsed tunable laser based spectrometer system. Droplets of chemical warfare agents, with a volume of 2 μl, were placed on a silicon surface and irradiated with sequences of laser pulses. The Raman scattering from V-series nerve agents, Tabun (GA) and Mustard gas (HD) was studied with the aim of finding the optimum parameters and the requirements for a detection system. A particular emphasis was put on V-agents that have been previously shown to yield relatively weak Raman scattering in this excitation band.

  5. Solar ultraviolet radiation induces biological alterations in human skin in vitro: Relevance of a well-balanced UVA/UVB protection

    Directory of Open Access Journals (Sweden)

    Françoise Bernerd

    2012-01-01

    Full Text Available Cutaneous damages such as sunburn, pigmentation, and photoaging are known to be induced by acute as well as repetitive sun exposure. Not only for basic research, but also for the design of the most efficient photoprotection, it is crucial to understand and identify the early biological events occurring after ultraviolet (UV exposure. Reconstructed human skin models provide excellent and reliable in vitro tools to study the UV-induced alterations of the different skin cell types, keratinocytes, fibroblasts, and melanocytes in a dose- and time-dependent manner. Using different in vitro human skin models, the effects of UV light (UVB and UVA were investigated. UVB-induced damages are essentially epidermal, with the typical sunburn cells and DNA lesions, whereas UVA radiation-induced damages are mostly located within the dermal compartment. Pigmentation can also be obtained after solar simulated radiation exposure of pigmented reconstructed skin model. Those models are also highly adequate to assess the potential of sunscreens to protect the skin from UV-associated damage, sunburn reaction, photoaging, and pigmentation. The results showed that an effective photoprotection is provided by broad-spectrum sunscreens with a potent absorption in both UVB and UVA ranges.

  6. Solar ultraviolet radiation induces biological alterations in human skin in vitro: relevance of a well-balanced UVA/UVB protection.

    Science.gov (United States)

    Bernerd, Francoise; Marionnet, Claire; Duval, Christine

    2012-06-01

    Cutaneous damages such as sunburn, pigmentation, and photoaging are known to be induced by acute as well as repetitive sun exposure. Not only for basic research, but also for the design of the most efficient photoprotection, it is crucial to understand and identify the early biological events occurring after ultraviolet (UV) exposure. Reconstructed human skin models provide excellent and reliable in vitro tools to study the UV-induced alterations of the different skin cell types, keratinocytes, fibroblasts, and melanocytes in a dose- and time-dependent manner. Using different in vitro human skin models, the effects of UV light (UVB and UVA) were investigated. UVB-induced damages are essentially epidermal, with the typical sunburn cells and DNA lesions, whereas UVA radiation-induced damages are mostly located within the dermal compartment. Pigmentation can also be obtained after solar simulated radiation exposure of pigmented reconstructed skin model. Those models are also highly adequate to assess the potential of sunscreens to protect the skin from UV-associated damage, sunburn reaction, photoaging, and pigmentation. The results showed that an effective photoprotection is provided by broad-spectrum sunscreens with a potent absorption in both UVB and UVA ranges.

  7. Application of the MASH v1.0 Code System to radiological warfare radiation threats

    International Nuclear Information System (INIS)

    Johnson, J.O.; Santoro, R.T.; Smith, M.S.

    1994-01-01

    Nuclear hardening capabilities of US and foreign ground force systems is a primary concern of the Department of Defense (DoD) and US Army. The Monte Carlo Adjoint Shielding Code System -- MASH v1.0 was developed at Oak Ridge National Laboratory (ORNL) to analyze these capabilities, i.e. the shielding effectiveness, for prompt radiation from a nuclear weapon detonation. Rapidly changing world events and the proliferation of nuclear weapons related technology have increased the kinds of nuclear threats to include intentionally dispersed radiation sources and fallout from tactical nuclear weapons used in the modern AirLand battlefield scenario. Consequently, a DoD area of increasing interest focuses on determining the shielding effectiveness of foreign and US armored vehicles to radiological warfare and fallout radiation threats. To demonstrate the applicability of MASH for analyzing dispersed radiation source problems, calculations have been completed for two distributed sources; a dispersed radiation environment simulated by a uniformly distributed 60 Co source, and a 235 U fission weapon fallout source. Fluence and dose assessments were performed for the free-field, the inside of a steel-walled two-meter box, in a phantom standing in the free-field, and in a phantom standing in the two-meter box. The results indicate substantial radiation protection factors for the 60 Co dispersed radiation source and the fallout source compared to the prompt radiation protection factors. The dose protection factors ranged from 40 to 95 for the two-meter box and from 55 to 123 for the mid-gut position of the phantom standing in the box. The results further indicate that a 60 Co source might be a good first order approximation for a tactical fission weapon fallout protection factor analysis

  8. Status of dental health in chemical warfare victims: the case of Isfahan, Iran.

    Science.gov (United States)

    Mottaghi, Ahmad; Hoseinzade, Abolfath; Zamani, Elham; Araghizade, Habib Allah

    2012-01-01

    Little evidence is available regarding the dental health of victims of chemical warfare in Iran. Therefore, in this study, we examined the decayed, missing, and filled teeth index (DMFT), community periodontal index of treatment needs (CPITN), and saliva secretion rate of chemical warfare victims living in the province of Isfahan in Iran. This case-control study was conducted with 300 chemical warfare victims as the treatment group and 300 age-matched individuals without exposure to chemical warfare as the control group. DMFT and CPITN indices and saliva secretion rate were measured and compared between the two groups. Chemical warfare victims had significantly higher scores than the control group for decayed teeth (4.25 ± 3.88 vs 3.52 ± 2.81; P=0.009), missing teeth (8.79 ± 9.3 vs 6.15 ± 8.43; Pwarfare victims was significantly lower than that in the control group (1.71 ± 0.05 vs 3.85 ± 1.95 cc/5 min; PChemical warfare victims have relatively poor dental/oral health. Chemical injury might cause a dysfunction in saliva secretion, with decrease in saliva secretion increasing the risk for tooth decay and periodontal disorders. Further research is required to find out the exact underlying mechanisms and the factors associated with poor dental/oral health in chemical warfare victims.

  9. Enhanced formulations for neutralization of chemical, biological and industrial toxants

    Science.gov (United States)

    Tucker, Mark D [Albuqueque, NM

    2008-06-24

    An enhanced formulation and method of making that neutralizes the adverse health effects of both chemical and biological compounds, especially chemical warfare (CW) and biological warfare (BW) agents, and toxic industrial chemicals. The enhanced formulation according to the present invention is non-toxic and non-corrosive and can be delivered by a variety of means and in different phases. The formulation provides solubilizing compounds that serve to effectively render the chemical and biological compounds, particularly CW and BW compounds, susceptible to attack, and at least one reactive compound that serves to attack (and detoxify or kill) the compound. The formulation includes at least one solubilizing agent, a reactive compound, a bleaching activator and water.

  10. Radiation protection

    International Nuclear Information System (INIS)

    1989-01-01

    A NRPB leaflet in the 'At-a-Glance' series explains in a simple but scientifically accurate way what radiation is, the biological effects and the relative sensitivity of different parts of the human body. The leaflet then discusses radiation protection principles, radiation protection in the UK and finally the effectiveness of this radiation protection as judged by a breakdown of the total dose received by an average person in the UK, a heavy consumer of Cumbrian seafood, an average nuclear industry worker and an average person in Cornwall. (UK)

  11. [Principles of management in biological infections].

    Science.gov (United States)

    Płusa, Tadeusz

    2012-11-01

    The effectiveness of the management in respiratory infection is depending on the nature of the biological pathogen and the immune status of the patient. For this reason, providing assistance to victims the organ function support, similarly as defining the pathogen and targeted antibiotic therapy should be applied. Available diagnostic tests provide rapid ability to identify the pathogen and antibiotics are able to control infection. Lack of efficacy of treatment may indicate the diversity of the pathogen than previously known and raises suspicion of biological warfare pathogen.

  12. Punishment sustains large-scale cooperation in prestate warfare

    Science.gov (United States)

    Mathew, Sarah; Boyd, Robert

    2011-01-01

    Understanding cooperation and punishment in small-scale societies is crucial for explaining the origins of human cooperation. We studied warfare among the Turkana, a politically uncentralized, egalitarian, nomadic pastoral society in East Africa. Based on a representative sample of 88 recent raids, we show that the Turkana sustain costly cooperation in combat at a remarkably large scale, at least in part, through punishment of free-riders. Raiding parties comprised several hundred warriors and participants are not kin or day-to-day interactants. Warriors incur substantial risk of death and produce collective benefits. Cowardice and desertions occur, and are punished by community-imposed sanctions, including collective corporal punishment and fines. Furthermore, Turkana norms governing warfare benefit the ethnolinguistic group, a population of a half-million people, at the expense of smaller social groupings. These results challenge current views that punishment is unimportant in small-scale societies and that human cooperation evolved in small groups of kin and familiar individuals. Instead, these results suggest that cooperation at the larger scale of ethnolinguistic units enforced by third-party sanctions could have a deep evolutionary history in the human species. PMID:21670285

  13. China's Use of Cyber Warfare: Espionage Meets Strategic Deterrence

    Directory of Open Access Journals (Sweden)

    Magnus Hjortdal

    2011-01-01

    Full Text Available This article presents three reasons for states to use cyber warfare and shows that cyberspace is—and will continue to be—a decisive element in China's strategy to ascend in the international system. The three reasons are: deterrence through infiltration of critical infrastructure; military technological espionage to gain military knowledge; and industrial espionage to gain economic advantage. China has a greater interest in using cyberspace offensively than other actors, such as the United States, since it has more to gain from spying on and deterring the United States than the other way around. The article also documents China's progress in cyber warfare and shows how it works as an extension of its traditional strategic thinking and the current debate within the country. Several examples of cyber attacks traceable to China are also presented. This includes cyber intrusions on a nuclear arms laboratory, attacks on defense ministries (including the Joint Strike Fighter and an airbase and the U.S. electric grid, as well as the current Google affair, which has proved to be a small part of a broader attack that also targeted the U.S. Government. There are, however, certain constraints that qualify the image of China as an aggressive actor in cyberspace. Some believe that China itself is the victim of just as many attacks from other states. Furthermore, certain actors in the United States and the West have an interest in overestimating China's capabilities in cyberspace in order to maintain their budgets.

  14. Biodiversity conservation and armed conflict: a warfare ecology perspective.

    Science.gov (United States)

    Hanson, Thor

    2018-04-23

    The activities involved in preparing for, executing, and recovering from armed conflict are globally pervasive and consequential, with significant impacts on natural systems. Effects on biodiversity are predominantly negative, produced by direct and indirect battlefield impacts, as well as the general breakdown of social, economic, and governance systems during wartime. Certain conservation opportunities do occur, however, particularly on lands set aside for training exercises, buffer zones, and peace parks. Here, the relationship between armed conflict and biodiversity is reviewed using the temporal framework of warfare ecology, which defines warfare as an ongoing process of three overlapping stages: preparations, war (armed conflict), and postwar activities. Several themes emerge from recent studies, including a heightened awareness of biodiversity conservation on military lands, the potential for scientific and conservation engagement to mitigate negative biodiversity impacts in war zones, and the importance of the postwar period for incorporating biodiversity priorities into reconstruction and recovery efforts. Research limitations and knowledge gaps are also discussed. © 2018 New York Academy of Sciences.

  15. Phytoalexin Elicitation- Potency As A Novel Technology for Biological Control and Protection Digitalis purpurea L. plants from Pre-Sowing Seed Treatment with Gamma Ray and Electric Current

    International Nuclear Information System (INIS)

    Bosila, H.A.; Lila, M.; Ahmed, T.E.S.

    2012-01-01

    Digitalis purpurea L seeds treated with gamma ray, (G) 0, 2.5, 5, 7.5 KR, and electric current (E), 0, 100, 150, 200 mA, then planted in splite-splite plot design for 3 replicates (R) and 2 successive seasons, in sandy soil irrigated with brackish water (900ppm) through surface drip irrigation system (SDI).The formed plants were foliar sprayed with manganese (M),0,3ppm-The formed Phytoalexin (PA) was bioassayed and chemically quantified.M3ppm could induce sistemic resistance (ISR) which initiate to farm 0.064, 0.070 mg PA 100mg fresh leaves. The formed PA exhibited PA-glycosidal structure wherefore, achieve therapeutic potency. (G) depress significantlly PA 73-91% of control while (E) activated (PA) significantly 134-154% of control. At (GE) interaction, such (G) dose PA increased significantlly by increasing (E) dose up to E200mA. Hence (E) efface a serious depression of (G). At (GEM) interaction, (G) 2.5, 5, 7.5 KR EO mA, M3ppm the formed. (PA) were; 91, 75, 63 were increased significantlly by increasing (E) dose up to E200mA M3ppm 128, 119, 109 – 129, 117, 107% of control for first and second season, respectively. Therefore, M elicitor application, in GEM combination, could be considered as a novel strategy for biological control and plant protection, from economic and environmental benefit point of view. It would occur by decreasing the cost of fungicides, bactericides and pesticides in Digitalis purpurea L biomass production, grown in extended agriculture area.

  16. A preliminary assessment of the effectiveness of the Mesoamerican Biological Corridor for protecting potential Baird's tapir (Tapirus bairdii) habitat in Southern Mexico.

    Science.gov (United States)

    Mendoza, Eduardo; Fuller, Trevon L; Thomassen, Henri A; Buermann, Wolfgang; Ramírez-Mejía, Diana; Smith, Thomas B

    2013-03-01

    Baird's tapir (Tapirus bairdii) is one of the most emblematic mammals of Mesoamerica, but like other large-bodied animals, it is facing an increasing risk of extinction due primarily to habitat loss. Mexico's 'ortion of the Mesoamerican Biological Corridor (MBC-M) is located in one of the main strongholds for Bairds tapir. To assess the MBC-M's effectiveness for tapir conservation, we estimated the distribution of the species' potential habitat by applying 2 modelling approaches (random forest and Maxent) to a set of uncorrelated environmental variables and a 157-point presence dataset. We calculated the extent of tapir habitat in within the MBC-M and modelled new corridors and conservation areas, which we compared to the MBC-M. Moreover, we assessed deforestation patterns in the region. Twenty-seven percent of highly suitable tapir habitat occurred in protected areas, 15% in corridors and 58.3% was outside the MBC-M and associated reserves. The spatial configuration of the MBC-M was partially concordant with the modelled set of conservation areas and corridors. The main dissimilarity was that the modelled corridors traversed forests in Belize and Guatemala to connect conservation areas. Analyses of deforestation since 1993 and human population density in the vicinity of the MBC-M indicated that future conservation efforts should give particular attention to the Montes Azules-El Triunfo Corridor due to greater habitat threat. The MBC-M has a great potential to play a prominent role in the conservation of tapir habitat but there is an urgent need to implement management plans that reinforce and complement this conservation initiative. © 2012 Wiley Publishing Asia Pty Ltd, ISZS and IOZ/CAS.

  17. Comparison of Three Sample Preparation Methods for Analysis of Chemical Warfare Agent Stimulants in Water

    International Nuclear Information System (INIS)

    Alessandro Sassolini

    2015-01-01

    Analytical chemistry in CBRNe (Chemical Biological Radiological Nuclear explosive) context requires not only high quality data; quickness, ruggedness and robustness are also mandatory. In this work, three samples preparation methods were compared using several organophosphorus pesticides as test compounds, used as stimulants of nerve CWA (Chemical Warfare Agents) to choose the one with best characteristics. Result was obtained better with the Dispersive Liquid-Liquid Micro Extraction (DLLME), relatively new in CBRNe field, obtaining uncertainty for different simulants between 8 and 15 % while a quantification limit between 0.01 and 0.08 μg/ l. To optimize this extraction method, different organo chlorinated solvents also tested but not relevant difference in these tests was obtained. In this work, all samples were analyzed by using a gas chromatography coupled with mass spectrometer (GC-MS) and also with Gas Chromatograph coupled with Nitrogen Phosphorous Detector (NPD) for DLLME samples to evaluate a low cost and rugged instrument adapt to field analytical methods with good performance in terms of uncertainty and sensibility even if poorer respect to the mass spectrometry. (author)

  18. Antioxidants as potential medical countermeasures for chemical warfare agents and toxic industrial chemicals.

    Science.gov (United States)

    McElroy, Cameron S; Day, Brian J

    2016-01-15

    The continuing horrors of military conflicts and terrorism often involve the use of chemical warfare agents (CWAs) and toxic industrial chemicals (TICs). Many CWA and TIC exposures are difficult to treat due to the danger they pose to first responders and their rapid onset that can produce death shortly after exposure. While the specific mechanism(s) of toxicity of these agents are diverse, many are associated either directly or indirectly with increased oxidative stress in affected tissues. This has led to the exploration of various antioxidants as potential medical countermeasures for CWA/TIC exposures. Studies have been performed across a wide array of agents, model organisms, exposure systems, and antioxidants, looking at an almost equally diverse set of endpoints. Attempts at treating CWAs/TICs with antioxidants have met with mixed results, ranging from no effect to nearly complete protection. The aim of this commentary is to summarize the literature in each category for evidence of oxidative stress and antioxidant efficacy against CWAs and TICs. While there is great disparity in the data concerning methods, models, and remedies, the outlook on antioxidants as medical countermeasures for CWA/TIC management appears promising. Copyright © 2015 Elsevier Inc. All rights reserved.

  19. Information Warfare: Issues Associated with the Defense of DOD Computers and Computer Networks

    National Research Council Canada - National Science Library

    Franklin, Derek

    2002-01-01

    ... that may threaten the critical information pathways of the armed forces An analysis of the history of computer information warfare reveals that there was an embarrassing lack of readiness and defense...

  20. Cerium oxide for the destruction of chemical warfare agents: A comparison of synthetic routes

    Czech Academy of Sciences Publication Activity Database

    Janos, P.; Henych, Jiří; Pelant, O.; Pilařová, V.; Vrtoch, L.; Kormunda, M.; Mazanec, K.; Štengl, Václav

    2016-01-01

    Roč. 304, MAR (2016), s. 259-268 ISSN 0304-3894 Institutional support: RVO:61388980 Keywords : Cerium oxide * Chemical warfare agents * Organophosphate compounds * Decontamination Subject RIV: CA - Inorganic Chemistry Impact factor: 6.065, year: 2016

  1. From Douhet to drones, air warfare, and the evolution of targeting

    NARCIS (Netherlands)

    Osinga, F.P.B.; Roorda, M.P.; Ducheine, P.A.L.; Schmitt, M.N.; Osinga, F.P.B.

    2016-01-01

    Through the prism of the experience of air warfare, this chapter identifies key factors that have shaped targeting. These include technological developments, organizational structures, and processes and inter-service competition for scarce resources. Moreover, targeting is informed by perspectives

  2. Defense Base Closure and Realignment Budget Data for the Naval Surface Warfare Center

    National Research Council Canada - National Science Library

    1993-01-01

    ... and realignment military construction projects. This report provides the results of the audit related to the realignment of Naval Surface Warfare Centers elements in White Oak, Maryland, and Panama City, Florida, to Dahlgren, Virginia...

  3. CRUSER's Warfare Innovation Workshop Focused on Hybrid War in the Urban Littorals

    OpenAIRE

    Ehrlich, Michael

    2017-01-01

    News Stories Archive The Naval Postgraduate School (NPS) Consortium for Robotics and Unmanned Systems Education and Research, CRUSER, hosted its annual Warfare Innovation Workshop (WIW) in Glasgow Hall, Sept. 18-21.

  4. The Army Ground Forces Training for Mountain and Winter Warfare - Study No. 23

    National Research Council Canada - National Science Library

    Govan, Thomas

    1946-01-01

    This general study of the experiments in mountain and winter warfare training from 1940 to 1944 is designed as an introduction to the histories of the Mountain Training Center and The 10th Mountain...

  5. Optimizing Armed Forces Capabilities for Hybrid Warfare – New Challenge for Slovak Armed Forces

    Directory of Open Access Journals (Sweden)

    Peter PINDJÁK

    2015-09-01

    Full Text Available The paper deals with the optimization of military capabilities of the Slovak Armed Forces for conducting operations in a hybrid conflict, which represents one of the possible scenarios of irregular warfare. Whereas in the regular warfare adversaries intend to eliminate the centers of gravity of each other, most often command and control structures, in irregular conflicts, the center of gravity shifts towards the will and cognitive perception of the target population. Hybrid warfare comprises a thoroughly planned combination of conventional military approaches and kinetic operations with subversive, irregular activities, including information and cyber operations. These efforts are often accompanied by intensified activities of intelligence services, special operation forces, and even mercenary and other paramilitary groups. The development of irregular warfare capabilities within the Slovak Armed Forces will require a progressive transformation process that may turn the armed forces into a modern and adaptable element of power, capable of deployment in national and international crisis management operations.

  6. Surface Warfare Officer Retention: Analysis of Individual Ready Reserve Survey Data

    National Research Council Canada - National Science Library

    Stoker, Carol; Crawford, Alice

    2008-01-01

    ... (including morale and lack of mentoring), push both men and women out of the Navy. Nonetheless, the Navy s primary effort to improve retention has been to introduce the Surface Warfare Officer Continuation Pay (SWOCP...

  7. Understanding "Understanding" Flow for Network-Centric Warfare: Military Knowledge-Flow Mechanics

    National Research Council Canada - National Science Library

    Nissen, Mark

    2002-01-01

    Network-centric warfare (NCW) emphasizes information superiority for battlespace efficacy, but it is clear that the mechanics of how knowledge flows are just as important as those pertaining to the networks and communication...

  8. DRES Database of Methods for the Analysis of Chemical Warfare Agents

    National Research Council Canada - National Science Library

    D'Agostino, Paul

    1997-01-01

    .... Update of the database continues as an ongoing effort and the DRES Database of Methods for the Analysis of Chemical Warfare Agents is available panel in hardcopy form or as a softcopy Procite or Wordperfect file...

  9. The Rapier or the Club: The Relationship between Attrition and Maneuver Warfare

    National Research Council Canada - National Science Library

    Springman, Jeffrey A

    2006-01-01

    ...? This project compares the relationship between attrition and maneuver warfare. The study considers whether there are times when wars of attrition should be fought, and whether there are conditions that force wars of attrition...

  10. Diagnosis of Exposure to Chemical Warfare Agents: A Comprehensive Literature Survey 1990-2005

    National Research Council Canada - National Science Library

    Noort, D

    2006-01-01

    This report is an update of TNO report PML 2003-A63. In this report an overview is presented of the methods currently available for detection of exposure to a number of chemical warfare agents (CWA), i.e...

  11. Anxiety, depression, and posttraumatic stress in Iranian survivors of chemical warfare.

    Science.gov (United States)

    Hashemian, Farnoosh; Khoshnood, Kaveh; Desai, Mayur M; Falahati, Farahnaz; Kasl, Stanislav; Southwick, Steven

    2006-08-02

    In the 1980-1988 Iran-Iraq War, extensive use of chemical weapons resulted in high rates of morbidity and mortality. While much is known about the physical consequences of chemical warfare, there is a paucity of information about the long-term effects of chemical attacks on mental health. To assess the long-term psychological impact of chemical warfare on a civilian population. Cross-sectional randomized survey conducted in July 2004 of 153 civilians in 3 towns exposed to warfare in northwestern Iran: Oshnaviyeh (low-intensity conventional warfare), Rabat (high-intensity conventional warfare), and Sardasht (both high-intensity conventional warfare and chemical weapons). Full or partial posttraumatic stress disorder (PTSD) diagnosis, anxiety symptoms, and depressive symptoms were assessed using Farsi versions of the Clinician-Administered PTSD Scale, Hamilton Scale for Anxiety, and Beck Depression Inventory, respectively. Overall participation rate was 93%. Respondents had a mean age of 45 years and were all of Kurdish ethnicity. Among individuals exposed to both high-intensity warfare and chemical weapons, prevalence rates for lifetime PTSD, current PTSD, major anxiety symptoms, and severe depressive symptoms were 59%, 33%, 65%, and 41%, respectively. Among the low-intensity warfare group, the corresponding rates were 8%, 2%, 18%, and 6%, respectively, while intermediate rates were found among those exposed to high-intensity warfare but not to chemical weapons (31%, 8%, 26%, and 12%, respectively). Compared with individuals exposed to low-intensity warfare, those exposed to both high-intensity warfare and chemical weapons were at higher risk for lifetime PTSD (odds ratio [OR], 18.6; 95% confidence interval [CI], 5.8-59.4), current PTSD (OR, 27.4; 95% CI, 3.4-218.2), increased anxiety symptoms (OR, 14.6; 95% CI, 6.0-35.6), and increased depressive symptoms (OR, 7.2; 95% CI, 3.3-15.9). Exposure to high-intensity warfare but not to chemical weapons was also

  12. Improving Blood Monitoring of Enzymes as Biomarkers of Risk from Anticholinergic Pesticides and Chemical Warfare Agents

    National Research Council Canada - National Science Library

    Wilson, Barry W

    2006-01-01

    Blood biomarkers are an important way to monitor exposure to anticholinergic pesticides and chemical warfare agents and to establish whether some personnel are at greater risk than others from exposure...

  13. Second NATO/SIBCA Exercise on Sampling of Chemical Warfare Agents

    National Research Council Canada - National Science Library

    Wils, E

    1999-01-01

    In order to practise the sampling of chemical warfare agents under realistic conditions, the Netherlands participated successfully in the second NATO/SIBCA sampling exercise conducted in Poland on 1-3...

  14. The Third World War? In The Cyberspace. Cyber Warfare in the Middle East.

    Directory of Open Access Journals (Sweden)

    Martina

    2014-06-01

    Full Text Available This article aims to provide a brief and comprehensive introduction to the issue of cyber warfare and to display the recent development in this area. Geographically, it focuses on the Middle East region, since the vast majority of the most important recent cyber attacks appeared just in there or were connected to it. The first part of the article tries to define the key notion of cyber warfare, compares it to the standard warfare and presents different types of cyber weapons that are known today. The second part points out examples of the most striking recent cyber attacks and uses them as evidences to demonstrate today's importance and dissemination of cyber warfare. Finally, the article sums up pros and cons of the cyber weapons and, in view of these, predicts a significant increase in their use in any future war conflicts.

  15. Improving Blood Monitoring of Enzymes as Biomarkers of Risk from Anticholinergic Pesticides and Chemical Warfare Agents

    National Research Council Canada - National Science Library

    Wilson, Barry W

    2005-01-01

    Blood biomarkers are an important way to monitor exposure to anticholinergic pesticides and chemical warfare agents and to establish whether some personnel are at greater risk than others from exposure...

  16. Special Operations Forces: C-130 Upgrade Plan Could Help Fix Electronic Warfare Deficiencies

    National Research Council Canada - National Science Library

    1998-01-01

    In response to a concern that threats to the U.S. Special Operations Command's (USSOCOM) aircraft are increasing, while funds available for electronic warfare are decreasing, the General Accounting Office...

  17. Combinatorial Auction Theory Applied to the Selection of Surface Warfare Officer Retention Incentives

    National Research Council Canada - National Science Library

    Denmond, Constance M; Johnson, Derek N; Lewis, Chavius G; Zegley, Christopher R

    2007-01-01

    The purpose of this project is to investigate the potential retention and cost impacts of offering combinations of retention base incentives to members of the Surface Warfare Officer (SWO) community...

  18. Cyber crime and cyber warfare with international cyber collaboration for RSA – preparing communities

    CSIR Research Space (South Africa)

    Grobler, M

    2012-03-01

    Full Text Available aspects come into play that may have an influence on the manner in which the military reacts to cyber attacks (Wilson 2007): ? new national security policy issues; ? consideration of psychological operations used to affect friendly nations... relationship between modern cyber space, cyber warfare and traditional legislation. As a starting point, cyber warfare is defined for the purpose of this article as the use of exploits in cyber space as a way to intentionally cause harm to people, assets...

  19. Modeling Anti-Air Warfare With Discrete Event Simulation and Analyzing Naval Convoy Operations

    Science.gov (United States)

    2016-06-01

    W., & Scheaffer, R. L. (2008). Mathematical statistics with applications . Belmont, CA: Cengage Learning. 118 THIS PAGE INTENTIONALLY LEFT BLANK...WARFARE WITH DISCRETE EVENT SIMULATION AND ANALYZING NAVAL CONVOY OPERATIONS by Ali E. Opcin June 2016 Thesis Advisor: Arnold H. Buss Co...REPORT DATE June 2016 3. REPORT TYPE AND DATES COVERED Master’s thesis 4. TITLE AND SUBTITLE MODELING ANTI-AIR WARFARE WITH DISCRETE EVENT

  20. Drone Warfare: Is the United States Violating the Law of Armed Conflict

    Science.gov (United States)

    2011-02-16

    NOTE AIR WAR COLLEGE AIR UNIVERSITY DRONE WARFARE: IS THE UNITED STATES VIOLATING THE LAW OF ARMED CONFLICT? by Barbara E. Shestko, Col...Base, Alabama. 1 Introduction The United States has become increasingly dependent upon the use of unmanned aircraft systems (UASs) or “ drones ” to...kill targeted members of al-Qaeda and the Taliban.1 Due to the success of drone warfare, we can expect the United States to continue its current

  1. Information Warfare on Social Media: A Brand Management Perspective

    Directory of Open Access Journals (Sweden)

    Kalpokas Ignas

    2017-06-01

    Full Text Available Employing a perspective informed by brand management, this article aims at understanding information warfare operations in social media. The state, seen as brand, must project an image of itself to both internal and foreign audiences to unite the domestic audience and/or attract global support. However, in constructing a brand, states are vulnerable to ‘sofa warriors’ – ordinary individuals who have been unwittingly recruited by hostile actors to disseminate (over social media or other platforms a counter-brand, harmful to the state concerned. These new threats are investigated in light of recent tendencies in online branding, elucidating their status as a national security threat, with the potential to significantly disrupt life in political communities.

  2. Book Review: Conquest in Cyberspace: National Security and Information Warfare

    Directory of Open Access Journals (Sweden)

    Gary C. Kessler

    2007-06-01

    Full Text Available Libicki, M.C. (2007. Conquest in Cyberspace: National Security and Information Warfare. New York: Cambridge University Press. 323 pages, ISBN: 978-0-521-69214-4 (paper, US$80Reviewed by Gary C. Kessler (gary.kessler@champlain.eduMany books -- and even movies ("Live Free or Die Hard" -- are based upon the premise of an impending information war. In these scenarios -- made all too plausible by the increased frequency with which we read about and experience major information security incidents -- a Bad Guy exploits known computer security vulnerabilities in order to control major national infrastructures via the Internet so as to reap financial, economic, and/or personal power.(see PDF for full review

  3. Nanostructured Metal Oxides for Stoichiometric Degradation of Chemical Warfare Agents.

    Science.gov (United States)

    Štengl, Václav; Henych, Jiří; Janoš, Pavel; Skoumal, Miroslav

    2016-01-01

    Metal oxides have very important applications in many areas of chemistry, physics and materials science; their properties are dependent on the method of preparation, the morphology and texture. Nanostructured metal oxides can exhibit unique characteristics unlike those of the bulk form depending on their morphology, with a high density of edges, corners and defect surfaces. In recent years, methods have been developed for the preparation of metal oxide powders with tunable control of the primary particle size as well as of a secondary particle size: the size of agglomerates of crystallites. One of the many ways to take advantage of unique properties of nanostructured oxide materials is stoichiometric degradation of chemical warfare agents (CWAs) and volatile organic compounds (VOC) pollutants on their surfaces.

  4. [Cutaneous and systemic toxicology of vesicants used in warfare].

    Science.gov (United States)

    Pita, R; Vidal-Asensi, S

    2010-01-01

    Vesicants are a group of chemicals used in warfare. The most representative agent is yperite, also known as mustard gas. The blisters that appeared on those exposed to yperite during combat in the First World War are responsible for the current name--vesicants--for this group of chemicals. Their affects are produced mainly through localized action of liquid or vapor forms on the skin, eyes, and respiratory tract. However, the high absorption of the liquid form through the skin or the vapor form on inhalation may cause substantial systemic effects. Here we analyze these effects, treatment of intoxication, and long-term sequelae, drawing on our experience and a review of the literature.

  5. An Open Architecture Framework for Electronic Warfare Based Approach to HLA Federate Development

    Directory of Open Access Journals (Sweden)

    HyunSeo Kang

    2018-01-01

    Full Text Available A variety of electronic warfare models are developed in the Electronic Warfare Research Center. An Open Architecture Framework for Electronic Warfare (OAFEw has been developed for reusability of various object models participating in the electronic warfare simulation and for extensibility of the electronic warfare simulator. OAFEw is a kind of component-based software (SW lifecycle management support framework. This OAFEw is defined by six components and ten rules. The purpose of this study is to construct a Distributed Simulation Interface Model, according to the rules of OAFEw, and create Use Case Model of OAFEw Reference Conceptual Model version 1.0. This is embodied in the OAFEw-FOM (Federate Object Model for High-Level Architecture (HLA based distributed simulation. Therefore, we design and implement EW real-time distributed simulation that can work with a model in C++ and MATLAB API (Application Programming Interface. In addition, OAFEw-FOM, electronic component model, and scenario of the electronic warfare domain were designed through simple scenarios for verification, and real-time distributed simulation between C++ and MATLAB was performed through OAFEw-Distributed Simulation Interface.

  6. A Survey of Game Theoretic Approaches to Modelling Decision-Making in Information Warfare Scenarios

    Directory of Open Access Journals (Sweden)

    Kathryn Merrick

    2016-07-01

    Full Text Available Our increasing dependence on information technologies and autonomous systems has escalated international concern for information- and cyber-security in the face of politically, socially and religiously motivated cyber-attacks. Information warfare tactics that interfere with the flow of information can challenge the survival of individuals and groups. It is increasingly important that both humans and machines can make decisions that ensure the trustworthiness of information, communication and autonomous systems. Subsequently, an important research direction is concerned with modelling decision-making processes. One approach to this involves modelling decision-making scenarios as games using game theory. This paper presents a survey of information warfare literature, with the purpose of identifying games that model different types of information warfare operations. Our contribution is a systematic identification and classification of information warfare games, as a basis for modelling decision-making by humans and machines in such scenarios. We also present a taxonomy of games that map to information warfare and cyber crime problems as a precursor to future research on decision-making in such scenarios. We identify and discuss open research questions including the role of behavioural game theory in modelling human decision making and the role of machine decision-making in information warfare scenarios.

  7. Recombinant Salmonella Expressing Burkholderia mallei LPS O Antigen Provides Protection in a Murine Model of Melioidosis and Glanders.

    Science.gov (United States)

    Moustafa, Dina A; Scarff, Jennifer M; Garcia, Preston P; Cassidy, Sara K B; DiGiandomenico, Antonio; Waag, David M; Inzana, Thomas J; Goldberg, Joanna B

    2015-01-01

    Burkholderia pseudomallei and Burkholderia mallei are the etiologic agents of melioidosis and glanders, respectively. These bacteria are highly infectious via the respiratory route and can cause severe and often fatal diseases in humans and animals. Both species are considered potential agents of biological warfare; they are classified as category B priority pathogens. Currently there are no human or veterinary vaccines available against these pathogens. Consequently efforts are directed towards the development of an efficacious and safe vaccine. Lipopolysaccharide (LPS) is an immunodominant antigen and potent stimulator of host immune responses. B. mallei express LPS that is structurally similar to that expressed by B. pseudomallei, suggesting the possibility of constructing a single protective vaccine against melioidosis and glanders. Previous studies of others have shown that antibodies against B. mallei or B. pseudomallei LPS partially protect mice against subsequent lethal virulent Burkholderia challenge. In this study, we evaluated the protective efficacy of recombinant Salmonella enterica serovar Typhimurium SL3261 expressing B. mallei O antigen against lethal intranasal infection with Burkholderia thailandensis, a surrogate for biothreat Burkholderia spp. in a murine model that mimics melioidosis and glanders. All vaccine-immunized mice developed a specific antibody response to B. mallei and B. pseudomallei O antigen and to B. thailandensis and were significantly protected against challenge with a lethal dose of B. thailandensis. These results suggest that live-attenuated SL3261 expressing B. mallei O antigen is a promising platform for developing a safe and effective vaccine.

  8. Recombinant Salmonella Expressing Burkholderia mallei LPS O Antigen Provides Protection in a Murine Model of Melioidosis and Glanders.

    Directory of Open Access Journals (Sweden)

    Dina A Moustafa

    Full Text Available Burkholderia pseudomallei and Burkholderia mallei are the etiologic agents of melioidosis and glanders, respectively. These bacteria are highly infectious via the respiratory route and can cause severe and often fatal diseases in humans and animals. Both species are considered potential agents of biological warfare; they are classified as category B priority pathogens. Currently there are no human or veterinary vaccines available against these pathogens. Consequently efforts are directed towards the development of an efficacious and safe vaccine. Lipopolysaccharide (LPS is an immunodominant antigen and potent stimulator of host immune responses. B. mallei express LPS that is structurally similar to that expressed by B. pseudomallei, suggesting the possibility of constructing a single protective vaccine against melioidosis and glanders. Previous studies of others have shown that antibodies against B. mallei or B. pseudomallei LPS partially protect mice against subsequent lethal virulent Burkholderia challenge. In this study, we evaluated the protective efficacy of recombinant Salmonella enterica serovar Typhimurium SL3261 expressing B. mallei O antigen against lethal intranasal infection with Burkholderia thailandensis, a surrogate for biothreat Burkholderia spp. in a murine model that mimics melioidosis and glanders. All vaccine-immunized mice developed a specific antibody response to B. mallei and B. pseudomallei O antigen and to B. thailandensis and were significantly protected against challenge with a lethal dose of B. thailandensis. These results suggest that live-attenuated SL3261 expressing B. mallei O antigen is a promising platform for developing a safe and effective vaccine.

  9. Limitations and challenges in treatment of acute chemical warfare agent poisoning.

    Science.gov (United States)

    Thiermann, Horst; Worek, Franz; Kehe, Kai

    2013-12-05

    Recent news from Syria on a possible use of chemical warfare agents made the headlines. Furthermore, the motivation of terrorists to cause maximal harm shifts these agents into the public focus. For incidents with mass casualties appropriate medical countermeasures must be available. At present, the most important threats arise from nerve agents and sulfur mustard. At first, self-protection and protection of medical units from contamination is of utmost importance. Volatile nerve agent exposure, e.g. sarin, results in fast development of cholinergic crisis. Immediate clinical diagnosis can be confirmed on-site by assessment of acetylcholinesterase activity. Treatment with autoinjectors that are filled with 2mg atropine and an oxime (at present obidoxime, pralidoxime, TMB-4 or HI-6) are not effective against all nerve agents. A more aggressive atropinisation has to be considered and more effective oximes (if possible with a broad spectrum or a combination of different oximes) as well as alternative strategies to cope with high acetylcholine levels at synaptic sites should be developed. A further gap exists for the treatment of patients with sustained cholinergic crisis that has to be expected after exposure to persistent nerve agents, e.g. VX. The requirement for long-lasting artificial ventilation can be reduced with an oxime therapy that is optimized by using the cholinesterase status for guidance or by measures (e.g. scavengers) that are able to reduce the poison load substantially in the patients. For sulfur mustard poisoning no specific antidote is available until now. Symptomatic measures as used for treatment of burns are recommended together with surgical or laser debridement. Thus, huge amounts of resources are expected to be consumed as wound healing is impaired. Possible depots of sulfur mustard in tissues may aggravate the situation. More basic knowledge is necessary to improve substantially therapeutic options. The use of stem cells may provide a new

  10. The effect of air permeability of chemical protective clothing material on clothing vapour resistance

    NARCIS (Netherlands)

    Havenith, G.; Vuister, R.; Wammes, L.

    1996-01-01

    One of the major problems associated with Chemical Warfare Protective Clothing (CW) is the additional heat load created by the garments. For CW-overgarments, research in the direction of reducing material thickness and thus heat and vapour resistance have not resulted in major improvements. The

  11. Tactic-operational problems of soldiers, civilians and environmental protection against contamination

    International Nuclear Information System (INIS)

    Krauze, M.

    1994-01-01

    The military problems connected with the probable use in warfare the chemical and nuclear weapon have been discussed. The concept of soldiers, civilians and environmental protection against the chemical and radiological contamination has been presented from the view point of military tactics

  12. The Abbott and Costello Effect: Who's on What, and What's Where When? A Human-Centered Method to Investigate Network Centric Warfare Systems

    National Research Council Canada - National Science Library

    Reed, Derek W

    2007-01-01

    ...), fundamentally changing how warfare is being conducted. Network centric warfare (NCW) systems are being rushed to the field and are offered as a solution for the fog of war and as a way to reduce manpower costs...

  13. Radiation protection seminar

    International Nuclear Information System (INIS)

    2012-01-01

    The Radiation Protection Seminar, was organized by the Argentina Association of Biology and Nuclear Medicine, and Bacon Laboratory, the 20 june 2012, in the Buenos Aires city of Argentina. In this event were presented some papers on the following topics: methods of decontamination, radiation protection of patients; concepts of radiation protection and dosimetry.

  14. Failing to protect humanitarian workers: lessons from Britain and Voluntary Aid Detachments in the Second World War.

    Science.gov (United States)

    Verma, Amol A

    2017-09-01

    This paper draws on official records of international and British organizations, newspaper reports, and volunteer memoirs to study the failure to protect humanitarian workers in the Second World War. The Second World War saw a significant expansion in the use of air warfare and flying missiles and these technological advances posed a grave threat to civilians and humanitarian workers. In this context, the International Committee of the Red Cross advocated unsuccessfully to restrict air warfare and create safe hospital zones. The British Government grappled with the tension between military and humanitarian objectives in setting its bombardment policy. Ultimately, humanitarian principles were neglected in pursuit of strategic aims, which endangered civilians and left humanitarian workers particularly vulnerable. British Voluntary Aid Detachment nurses experienced more than six-fold greater fatality rates than civil defence workers and the general population. The lessons from failures to protect humanitarian workers in the face of evolutions in warfare remain profoundly relevant.

  15. Rain-Induced Wash-Off of Chemical Warfare Agent (VX) from Foliar Surfaces of Living Plants Maintained in a Surety Hood

    Science.gov (United States)

    2016-09-01

    RAIN-INDUCED WASH-OFF OF CHEMICAL WARFARE AGENT (VX) FROM FOLIAR SURFACES OF LIVING PLANTS MAINTAINED IN A...Final 3. DATES COVERED (From - To) May 2014 – Sep 2015 4. TITLE AND SUBTITLE Rain-Induced Wash-Off of Chemical Warfare Agent (VX) from Foliar...galli Foliage Chemical warfare agent (CWA) O-ethyl-S-(2

  16. A comparison of the oral application and injection routes using the Onderstepoort Biological Products Fowl Typhoid vaccine, its safety, efficacy and duration of protection in commercial laying hens : article

    Directory of Open Access Journals (Sweden)

    C. Purchase

    2008-05-01

    Full Text Available This study was undertaken to establish whether the Onderstepoort Biological Products Fowl Typhoid (OBPft vaccine registered as an injectable vaccine was effective and safe when administered orally to commercial layers. Its efficacy and duration of protection were compared with application by intramuscular injection. Commercial brown layer hens were used as they were found to be highly susceptible to Salmonella gallinarum infections. In the vaccine safety trial birds were euthanased at timed intervals spanning 4 weeks post-vaccination. Necropsies were performed and samples were taken and tested. No clinical signs or mortalities could be attributed to the OBPft vaccine nor could active shedding of the vaccine strain be detected. Slight pathological changes were noted with both routes of vaccination; however, these changes were transient, returning to normal within the observation period. The injected groups showed a better serological response with the rapid serum plate agglutination (RSPA test than the orally vaccinated groups. In the duration of protection trial, birds were challenged at 3-8-week intervals post-vaccination. All unvaccinated birds died. Protection 8 and 16 weeks after vaccination was above 60 %, by 24 weeks after challenge, the vaccine protection was below 30 %. It was found that there was no significant difference (P < 0.05 in the protection offered by either the oral or injected route of vaccination with the OBPft vaccine.

  17. Guerilla Warfare & Law Enforcement: Combating the 21st Century Terrorist Cell within the U.S.

    Directory of Open Access Journals (Sweden)

    Major Richard Hughbank

    2009-01-01

    Full Text Available Both domestic and international terrorist organizations employ guerrilla warfare tactics, techniques, and procedures. Thus, the ability to identify and defeat the members of these organizations, cripple their infrastructures, and disrupt their financial resources lies in the understanding of modern guerrilla warfare as it develops in the twenty-first century within the United States.3 The forms of asymmetric warfare4 adopted by domestic and international terrorist groups alike is no longer intended to gain simple media exposure or governmental manipulation; they want to make an overpowering impact by causing massive loss of life and severe damage to infrastructure and are often motivated by religious imperatives and political goals. As terrorism analyst Stephen Flynn has observed, "Throughout the 20th century [Americans] were able to treat national security as essentially an out-of-body experience. When confronted by threats, [America] dealt with them on the turf of our allies or our adversaries. Aside from the occasional disaster and heinous crime, civilian life [in the United States] has been virtually terror-free." With the turn of the twenty-first century, terrorist operations have become more prevalent in the United States and are taking shape in the form of modern guerrilla warfare, thus creating new challenges for federal, state, and local law enforcement agencies. After reviewing the origin and nature of these challenges, this article will offer some suggestions for countering guerilla warfare in the United States.

  18. Developing Navy Capability to Recover Forces in Chemical, Biological, and Radiological Hazard Environments

    Science.gov (United States)

    2013-01-01

    damage control; LHD flight deck and well deck operations; fleet surgical team; Afloat Training Group; Assault Craft Unit; Naval Surface Warfare Center ...Biological, Radiological and Nuclear School, and U.S. Army Edgewood Chemical Biological Center , Guidelines for Mass Casualty Decontamination During a HAZMAT...Policy Center of the RAND National Defense Research Institute, a federally funded research and development center sponsored by OSD, the Joint Staff

  19. Advances in toxicology and medical treatment of chemical warfare nerve agents

    Science.gov (United States)

    2012-01-01

    Organophosphorous (OP) Nerve agents (NAs) are known as the deadliest chemical warfare agents. They are divided into two classes of G and V agents. Most of them are liquid at room temperature. NAs chemical structures and mechanisms of actions are similar to OP pesticides, but their toxicities are higher than these compounds. The main mechanism of action is irreversible inhibition of Acetyl Choline Esterase (AChE) resulting in accumulation of toxic levels of acetylcholine (ACh) at the synaptic junctions and thus induces muscarinic and nicotinic receptors stimulation. However, other mechanisms have recently been described. Central nervous system (CNS) depression particularly on respiratory and vasomotor centers may induce respiratory failure and cardiac arrest. Intermediate syndrome after NAs exposure is less common than OP pesticides poisoning. There are four approaches to detect exposure to NAs in biological samples: (I) AChE activity measurement, (II) Determination of hydrolysis products in plasma and urine, (III) Fluoride reactivation of phosphylated binding sites and (IV) Mass spectrometric determination of cholinesterase adducts. The clinical manifestations are similar to OP pesticides poisoning, but with more severity and fatalities. The management should be started as soon as possible. The victims should immediately be removed from the field and treatment is commenced with auto-injector antidotes (atropine and oximes) such as MARK I kit. A 0.5% hypochlorite solution as well as novel products like M291 Resin kit, G117H and Phosphotriesterase isolated from soil bacterias, are now available for decontamination of NAs. Atropine and oximes are the well known antidotes that should be infused as clinically indicated. However, some new adjuvant and additional treatment such as magnesium sulfate, sodium bicarbonate, gacyclidine, benactyzine, tezampanel, hemoperfusion, antioxidants and bioscavengers have recently been used for OP NAs poisoning. PMID:23351280

  20. Potential Science and Technology Game Changers for the Ground Warfare of 2050: Selected Projections Made in 2017

    Science.gov (United States)

    2018-02-01

    ARL-TR-8283 ● FEB 2018 US Army Research Laboratory Potential Science and Technology Game Changers for the Ground Warfare of 2050...Science and Technology Game Changers for the Ground Warfare of 2050: Selected Projections Made in 2017 by Alexander Kott Office of the Director...Brian Sadler Vehicle Technology Directorate, ARL Ananthram Swami Computational and Information Sciences Directorate, ARL Approved for

  1. Use of Nuclear Techniques in Biological Control: Managing Pests, Facilitating Trade and Protecting the Environment. Report of a Consultants Group Meeting. Working Material

    International Nuclear Information System (INIS)

    1999-01-01

    High-priority opportunities are proposed for use of nuclear techniques to effect improved production and shipping of augmentative biological control agents. Proposed subprojects include use of ionizing radiation to improve the production of insect natural enemies on natural hosts/prey or on artificial diets. Other subprojects pertain to improving the ability to move beneficial organisms in international trade, and in using them in the field. Additional high priority activities were identified proposing use of nuclear techniques to produce sterile and/or substerile F-1 weed biological control agents to help evaluate potential impact on non-target species in the pre-release phase, integration of augmentative releases and F-1 sterility in IPM and area-wide pest management programmes, and utilization of by-products from SIT mass-rearing facilities in augmentative biological control programmes. (author)

  2. Methods of Advanced Wound Management for Care of Combined Traumatic and Chemical Warfare Injuries

    Science.gov (United States)

    Graham, John S.; Gerlach, Travis W.; Logan, Thomas P.; Bonar, James P.; Fugo, Richard J.; Lee, Robyn B.; Coatsworth, Matthew A.

    2008-01-01

    Objective: Chemical warfare agents are potential threats to military personnel and civilians. The potential for associated traumatic injuries is significant. Damage control surgery could expose medical personnel to agents contaminating the wounds. The objectives of this study were to demonstrate efficacy of surgical decontamination and assess exposure risk to attending personnel. Methods: Weanling pigs were randomly assigned to 2 of 4 debridement tools (scalpel, Bovie® knife, Fugo Blade®, and Versajet™ Hydrosurgery System). Penetrating traumatic wounds were created over the shoulder and thigh and then exposed to liquid sulfur mustard (HD) for 60 minutes. Excisional debridement of the injuries was performed while vapors over each site were collected. Gas chromatography was used to measure HD in samples of collected vapors. Unbound HD was quantified in presurgical wound swabs, excised tissues, and peripheral tissue biopsies following solvent extraction. Results: Excisional debridement produced agent-free wound beds (surgical decontamination). A significant amount of HD vapor was detected above the surgical fields with each tool. Apart from the Versajet™ producing significantly lower levels of HD detected over thigh wounds compared with those treated using the scalpel, there were no differences in the amount of agent detected among the tools. All measured levels significantly exceeded established safety limits. Vesicating levels of unbound HD were extracted from excised tissue. There was no measured lateral spreading of HD beyond the surgical margins. Conclusions: There is significant occupational exposure risk to HD during surgical procedures designed to stabilize agent-contaminated wounds. If appropriate protective measures are taken, surgical decontamination is both effective and safe. PMID:18716652

  3. Naval Undersea Warfare Center Division Newport utilities metering, Phase 1

    Energy Technology Data Exchange (ETDEWEB)

    Carroll, D.M.

    1992-11-01

    Pacific Northwest Laboratory developed this report for the US Navy`s Naval Undersea Warfare Center Division Newport, Rhode Island (NUWC). The purpose of the report was to review options for metering electricity and steam used in the NUWC compound, and to make recommendations to NUWC for implementation under a follow-on project. An additional NUWC concern is a proposed rate change by the servicing utility, Newport Electric, which would make a significant shift from consumption to demand billing, and what effect that rate change would have on the NUWC utility budget. Automated, remote reading meters are available which would allow NUWC to monitor its actual utility consumption and demand for both the entire NUWC compound and by end-use in individual buildings. Technology is available to perform the meter reads and manipulate the data using a personal computer with minimal staff requirement. This is not meant to mislead the reader into assuming that there is no requirement for routine preventive maintenance. All equipment requires routine maintenance to maintain its accuracy. While PNL reviewed the data collected during the site visit, however, it became obvious that significant opportunities exist for reducing the utility costs other than accounting for actual consumption and demand. Unit costs for both steam and electricity are unnecessarily high, and options are presented in this report for reducing them. Additionally, NUWC has an opportunity to undertake a comprehensive energy resource management program to significantly reduce its energy demand, consumption, and costs.

  4. Naval Undersea Warfare Center Division Newport utilities metering, Phase 1

    Energy Technology Data Exchange (ETDEWEB)

    Carroll, D.M.

    1992-11-01

    Pacific Northwest Laboratory developed this report for the US Navy's Naval Undersea Warfare Center Division Newport, Rhode Island (NUWC). The purpose of the report was to review options for metering electricity and steam used in the NUWC compound, and to make recommendations to NUWC for implementation under a follow-on project. An additional NUWC concern is a proposed rate change by the servicing utility, Newport Electric, which would make a significant shift from consumption to demand billing, and what effect that rate change would have on the NUWC utility budget. Automated, remote reading meters are available which would allow NUWC to monitor its actual utility consumption and demand for both the entire NUWC compound and by end-use in individual buildings. Technology is available to perform the meter reads and manipulate the data using a personal computer with minimal staff requirement. This is not meant to mislead the reader into assuming that there is no requirement for routine preventive maintenance. All equipment requires routine maintenance to maintain its accuracy. While PNL reviewed the data collected during the site visit, however, it became obvious that significant opportunities exist for reducing the utility costs other than accounting for actual consumption and demand. Unit costs for both steam and electricity are unnecessarily high, and options are presented in this report for reducing them. Additionally, NUWC has an opportunity to undertake a comprehensive energy resource management program to significantly reduce its energy demand, consumption, and costs.

  5. Simulation-based planning for theater air warfare

    Science.gov (United States)

    Popken, Douglas A.; Cox, Louis A., Jr.

    2004-08-01

    Planning for Theatre Air Warfare can be represented as a hierarchy of decisions. At the top level, surviving airframes must be assigned to roles (e.g., Air Defense, Counter Air, Close Air Support, and AAF Suppression) in each time period in response to changing enemy air defense capabilities, remaining targets, and roles of opposing aircraft. At the middle level, aircraft are allocated to specific targets to support their assigned roles. At the lowest level, routing and engagement decisions are made for individual missions. The decisions at each level form a set of time-sequenced Courses of Action taken by opposing forces. This paper introduces a set of simulation-based optimization heuristics operating within this planning hierarchy to optimize allocations of aircraft. The algorithms estimate distributions for stochastic outcomes of the pairs of Red/Blue decisions. Rather than using traditional stochastic dynamic programming to determine optimal strategies, we use an innovative combination of heuristics, simulation-optimization, and mathematical programming. Blue decisions are guided by a stochastic hill-climbing search algorithm while Red decisions are found by optimizing over a continuous representation of the decision space. Stochastic outcomes are then provided by fast, Lanchester-type attrition simulations. This paper summarizes preliminary results from top and middle level models.

  6. Drone Warfare: Twenty-First Century Empire and Communications

    Directory of Open Access Journals (Sweden)

    Kevin Howley

    2017-02-01

    Full Text Available This paper, part of a larger project that examines drones from a social-construction of technology perspective, considers drone warfare in light of Harold Innis’s seminal work on empire and communication. Leveraging leading-edge aeronautics with advanced optics, data processing, and networked communication, drones represent an archetypal “space-biased” technology. Indeed, by allowing remote operators and others to monitor, select, and strike targets from half a world away, and in real-time, these weapon systems epitomize the “pernicious neglect of time” Innis sought to identify and remedy in his later writing. With Innis’s time-space dialectic as a starting point, then, the paper considers drones in light of a longstanding paradox of American culture: the impulse to collapse the geographical distance between the United States and other parts of the globe, while simultaneously magnifying the cultural difference between Americans and other peoples and societies. In the midst of the worldwide proliferation of drones, this quintessentially sublime technology embodies this (disconnect in important, profound, and ominous ways.

  7. Prevalence of Asthma in Children of Chemical Warfare Victims

    Science.gov (United States)

    Mirsadraee, Majid; Mozaffari, Abolfazl; Attaran, Davood

    2011-01-01

    Objective Exposure of DNA to sulfur mustard gas may increase the inheritance of asthma in chemical warfare victims' (CWV) offspring. The objective of this study was to determine the prevalence of asthma in children of CWV and compare it to asthmatic children in the general population. Methods Four hundred and nine children from 130 CWV fathers and 440 children from 145 asthmatic parents from two cities in Iran participated in this study. The prevalence of asthma was determined by standard questionnaire released for epidemiological survey of asthma in children and compared between two groups. Findings The prevalence of asthma in the CWV group was 15%; this was not significantly different from the control group (12.5%). The children of the CWV group reported a significantly greater incidence of wheezing (1.2±3.1 attacks) per year, but the control group reported more severe attacks leading to speech difficulties (3%) and coughing (7%). Regression analysis showed that with increasing family size in the control group, the number of subjects suffering from asthmatic symptoms decreases significantly (r=0.86, P=0.001). Conclusion Chemical agents may increase the prevalence of asthma in the offspring of CWV. PMID:23056804

  8. Studies on residue-free decontaminants for chemical warfare agents.

    Science.gov (United States)

    Wagner, George W

    2015-03-17

    Residue-free decontaminants based on hydrogen peroxide, which decomposes to water and oxygen in the environment, are examined as decontaminants for chemical warfare agents (CWA). For the apparent special case of CWA on concrete, H2O2 alone, without any additives, effectively decontaminates S-2-(diisopropylamino)ethyl O-ethyl methylphosphonothioate (VX), pinacolyl methylphosphorofluoridate (GD), and bis(2-choroethyl) sulfide (HD) in a process thought to involve H2O2 activation by surface-bound carbonates/bicarbonates (known H2O2 activators for CWA decontamination). A plethora of products are formed during the H2O2 decontamination of HD on concrete, and these are characterized by comparison to synthesized authentic compounds. As a potential residue-free decontaminant for surfaces other than concrete (or those lacking adsorbed carbonate/bicarbonate) H2O2 activation for CWA decontamination is feasible using residue-free NH3 and CO2 as demonstrated by reaction studies for VX, GD, and HD in homogeneous solution. Although H2O2/NH3/CO2 ("HPAC") decontaminants are active for CWA decontamination in solution, they require testing on actual surfaces of interest to assess their true efficacy for surface decontamination.

  9. Atmospheric Pressure Plasma-Electrospin Hybrid Process for Protective Applications

    Science.gov (United States)

    Vitchuli Gangadharan, Narendiran

    2011-12-01

    Chemical and biological (C-B) warfare agents like sarin, sulfur mustard, anthrax are usually dispersed into atmosphere in the form of micro aerosols. They are considered to be dangerous weapon of mass destruction next to nuclear weapons. The airtight protective clothing materials currently available are able to stop the diffusion of threat agents but not good enough to detoxify them, which endangers the wearers. Extensive research efforts are being made to prepare advanced protective clothing materials that not only prevent the diffusion of C-B agents, but also detoxify them into harmless products thus ensuring the safety and comfort of the wearer. Electrospun nanofiber mats are considered to have effective filtration characteristics to stop the diffusion of submicron level particulates without sacrificing air permeability characteristics and could be used in protective application as barrier material. In addition, functional nanofibers could be potentially developed to detoxify the C-B warfare threats into harmless products. In this research, electrospun nanofibers were deposited on fabric surface to improve barrier efficiency without sacrificing comfort-related properties of the fabrics. Multi-functional nanofibers were fabricated through an electrospinning-electrospraying hybrid process and their ability to detoxify simulants of C-B agents was evaluated. Nanofibers were also deposited onto plasma-pretreated woven fabric substrate through a newly developed plasma-electrospinning hybrid process, to improve the adhesive properties of nanofibers on the fabric surface. The nanofiber adhesion and durability properties were evaluated by peel test, flex and abrasion resistance tests. In this research work, following tasks have been carried out: i) Controlled deposition of nanofiber mat onto woven fabric substrate Electrospun Nylon 6 fiber mats were deposited onto woven 50/50 Nylon/Cotton fabric with the motive of making them into protective material against submicron

  10. Effects of lactoferrin derived peptides on simulants of biological warfare agents

    NARCIS (Netherlands)

    Sijbrandij, T.; Ligtenberg, Antoon J.; Nazmi, K.; Veerman, Enno C. I.; Bolscher, Jan G. M.; Bikker, Floris J.

    2017-01-01

    Lactoferrin (LF) is an important immune protein in neutrophils and secretory fluids of mammals. Bovine LF (bLF) harbours two antimicrobial stretches, lactoferricin and lactoferampin, situated in close proximity in the N1 domain. To mimic these antimicrobial domain parts a chimeric peptide

  11. Effects of lactoferrin derived peptides on simulants of biological warfare agents

    OpenAIRE

    Sijbrandij, Tjitske; Ligtenberg, Antoon J.; Nazmi, Kamran; Veerman, Enno C. I.; Bolscher, Jan G. M.; Bikker, Floris J.

    2016-01-01

    Lactoferrin (LF) is an important immune protein in neutrophils and secretory fluids of mammals. Bovine LF (bLF) harbours two antimicrobial stretches, lactoferricin and lactoferampin, situated in close proximity in the N1 domain. To mimic these antimicrobial domain parts a chimeric peptide (LFchimera) has been constructed comprising parts of both stretches (LFcin17–30 and LFampin265–284). To investigate the potency of this construct to combat a set of Gram positive and Gram negative bacteria w...

  12. Biological Warfare Improved Response Program (BW-IRP) CDC/DoD Smallpox Workshop

    Science.gov (United States)

    2005-01-01

    attack. In April 2000, the container of virus is smuggled across the boarder, overland from Mexico . It is released on April 15th aboard Fat Chance...them give a firm history of childhood chicken pox, she becomes concerned and sends specimens to a lab to rule out varicella (Chicken Pox). She checks...hands and notes the students history of childhood chickenpox. Laboratory testing to rule out varicella is also ordered. When that result is negative

  13. Distinct human antibody response to the biological warfare agent Burkholderia mallei.

    Science.gov (United States)

    Varga, John J; Vigil, Adam; DeShazer, David; Waag, David M; Felgner, Philip; Goldberg, Joanna B

    2012-10-01

    The genetic similarity between Burkholderia mallei (glanders) and Burkholderia pseudomallei (melioidosis) had led to the general assumption that pathogenesis of each bacterium would be similar. In 2000, the first human case of glanders in North America since 1945 was reported in a microbiology laboratory worker. Leveraging the availability of pre-exposure sera for this individual and employing the same well-characterized protein array platform that has been previously used to study a large cohort of melioidosis patients in southeast Asia, we describe the antibody response in a human with glanders. Analysis of 156 peptides present on the array revealed antibodies against 17 peptides with a > 2-fold increase in this infection. Unexpectedly, when the glanders data were compared with a previous data set from B. pseudomallei infections, there were only two highly increased antibodies shared between these two infections. These findings have implications in the diagnosis and treatment of B. mallei and B. pseudomallei infections.

  14. Chicken cathelicidin-2-derived peptides with enhanced immunomodulatory and antibacterial activities against biological warfare agents

    NARCIS (Netherlands)

    Molhoek, E.M.; Dijk, A. van; Veldhuizen, E.J.A.; Dijk-Knijnenburg, H.; Mars-Groenendijk, R.H.; Boele, L.C.L.; Kaman-van Zanten, W.E.; Haagsman, H.P.; Bikker, F.J.

    2010-01-01

    Host defence peptides (HDPs) are considered to be excellent candidates for the development of novel therapeutic agents. Recently, it was demonstrated that the peptide C1-15, an N-terminal segment of chicken HDP cathelicidin-2, exhibits potent antibacterial activity while lacking cytotoxicity towards

  15. The DTIC Review: Volume 2, Number 4, Surviving Chemical and Biological Warfare

    Science.gov (United States)

    1996-12-01

    formulated with PA strategic defeat. plus Monophosphoryl Lipid A (MPL) in a Squalenel Lecithin / Tween 80 emulsion (SLT) and PA plus the saponin QS-21...PIGS, LYOPHILIZATION, IMMUNOGENS, LECITHIN . IDENTIFIERS: (U) MPL (MONOPHOSPHORYL LIPID A), SLT(SQUELENEL LECITHIN /TWEEN) + Included in The DTIC Review...mass spectrometric methods have and expressed in E. coli, and has been shown to hydrolyze the been developed as independent highly sensitive techniques

  16. Reduced weight decontamination formulation for neutralization of chemical and biological warfare agents

    Science.gov (United States)

    Tucker, Mark D.

    2014-06-03

    A reduced weight DF-200 decontamination formulation that is stable under high temperature storage conditions. The formulation can be pre-packed as an all-dry (i.e., no water) or nearly-dry (i.e., minimal water) three-part kit, with make-up water (the fourth part) being added later in the field at the point of use.

  17. Decontamination of chemical and biological warfare (CBW) agents using an atmospheric pressure plasma jet (APPJ)

    International Nuclear Information System (INIS)

    Herrmann, H.W.; Henins, I.; Park, J.; Selwyn, G.S.

    1999-01-01

    The atmospheric pressure plasma jet (APPJ) [A. Schuetze et al., IEEE Trans. Plasma Sci. 26, 1685 (1998)] is a nonthermal, high pressure, uniform glow plasma discharge that produces a high velocity effluent stream of highly reactive chemical species. The discharge operates on a feedstock gas (e.g., He/O 2 /H 2 O), which flows between an outer, grounded, cylindrical electrode and an inner, coaxial electrode powered at 13.56 MHz rf. While passing through the plasma, the feedgas becomes excited, dissociated or ionized by electron impact. Once the gas exits the discharge volume, ions and electrons are rapidly lost by recombination, but the fast-flowing effluent still contains neutral metastable species (e.g., O 2 * , He * ) and radicals (e.g., O, OH). This reactive effluent has been shown to be an effective neutralizer of surrogates for anthrax spores and mustard blister agent. Unlike conventional wet decontamination methods, the plasma effluent does not cause corrosion and it does not destroy wiring, electronics, or most plastics, making it highly suitable for decontamination of sensitive equipment and interior spaces. Furthermore, the reactive species in the effluent rapidly degrade into harmless products leaving no lingering residue or harmful by-products. copyright 1999 American Institute of Physics

  18. Decontamination of chemical and biological warfare (CBW) agents using an atmospheric pressure plasma jet (APPJ)

    Science.gov (United States)

    Herrmann, H. W.; Henins, I.; Park, J.; Selwyn, G. S.

    1999-05-01

    The atmospheric pressure plasma jet (APPJ) [A. Schütze et al., IEEE Trans. Plasma Sci. 26, 1685 (1998)] is a nonthermal, high pressure, uniform glow plasma discharge that produces a high velocity effluent stream of highly reactive chemical species. The discharge operates on a feedstock gas (e.g., He/O2/H2O), which flows between an outer, grounded, cylindrical electrode and an inner, coaxial electrode powered at 13.56 MHz rf. While passing through the plasma, the feedgas becomes excited, dissociated or ionized by electron impact. Once the gas exits the discharge volume, ions and electrons are rapidly lost by recombination, but the fast-flowing effluent still contains neutral metastable species (e.g., O2*, He*) and radicals (e.g., O, OH). This reactive effluent has been shown to be an effective neutralizer of surrogates for anthrax spores and mustard blister agent. Unlike conventional wet decontamination methods, the plasma effluent does not cause corrosion and it does not destroy wiring, electronics, or most plastics, making it highly suitable for decontamination of sensitive equipment and interior spaces. Furthermore, the reactive species in the effluent rapidly degrade into harmless products leaving no lingering residue or harmful by-products.

  19. Decontamination of Chemical/Biological Warfare (CBW) Agents Using an Atmospheric Pressure Plasma Jet (APPJ)

    Science.gov (United States)

    Herrmann, Hans W.

    1998-11-01

    The atmospheric pressure plasma jet (APPJ) is a non-thermal, high pressure, uniform glow discharge that produces a high velocity effluent stream of highly reactive chemical species. The discharge operates on a feedstock gas (e.g. He/O_2/H_2O) which flows between an outer, grounded, cylindrical electrode and an inner, coaxial electrode powered at 13.56 MHz RF. While passing through the plasma, the feedgas becomes excited, dissociated or ionized by electron impact. Once the gas exits the discharge volume, ions and electrons are rapidly lost by recombination, but the fast-flowing effluent still contains metastables (e.g. O2*, He*) and radicals (e.g. O, OH). These reactive species have been shown to be effective neutralizers of surrogates for anthrax spores, mustard blister agent and VX nerve gas. Unlike conventional, wet decontamination methods, the plasma effluent does not cause corrosion of most surfaces and does not damage wiring, electronics, nor most plastics. This makes it highly suitable for decontamination of high value sensitive equipment such as is found in vehicle interiors (i.e. tanks, planes...) for which there is currently no good decontamination technique. Furthermore, the reactive species rapidly degrade into harmless products leaving no lingering residue or harmful byproducts. Physics of the APPJ will be discussed and results of surface decontamination experiments using simulant and actual CBW agents will be presented.

  20. Identification of Biological Warfare (BW) Threat Agents Using Deoxyribonucleic Acid (DNA) Microarrays

    National Research Council Canada - National Science Library

    Schaudies, Paul R

    2005-01-01

    ...) antibiotic resistance genes, 4) virulence plasmid sequences and 5) ribosomal genes, we are in a unique position to develop a novel method for the identification and characterization of microorganism...

  1. Is the U.S. Navy Prepared to Counter Biological Warfare Threats?

    Science.gov (United States)

    2001-12-01

    Unit 731 set up flea “nurseries” for the production of 135 million plague-infested fleas every four months. As a delivery system, porcelain bombs...operations is important, naval doctrine and TTPs should allow NSF to conduct CM alone in an emergency.141 The Chinese have an ancient saying, “kill

  2. Integrated Biological Warfare Technology Platform (IBWTP). Intelligent Software Supporting Situation Awareness, Response, and Operations

    Science.gov (United States)

    2007-01-01

    phases of the technology, QLI used a common software development and maintenance environment, called the Quantum Leap Uber Build System (QLUBS). QLI...May be used in internal tools and application. Using internally developed code on internal application ( Eating your own dogfood) provides

  3. SiGe-based re-engineering of electronic warfare subsystems

    CERN Document Server

    Lambrechts, Wynand

    2017-01-01

    This book equips readers with a thorough understanding of the applicability of new-generation silicon-germanium (SiGe) electronic subsystems for the military purposes of electronic warfare and defensive countermeasures. The theoretical and technical background is extensively explained and all aspects of the integration of SiGe as an enabling technology for maritime, land, and airborne (including space) electronic warfare are addressed, including research, design, development, and implementation. The coverage is supported by mathematical derivations, informative illustrations, practical examples, and case studies. While SiGe technology provides speed, performance, and price advantages in many markets, sharing of information on its use in electronic warfare systems has to date been limited, especially in developing nations. This book will therefore be warmly welcomed as an engineering guideline that focuses especially on the speed and reliability of current-generation SiGe circuits and highlights emerging innov...

  4. THE CYBER DIMENSION OF MODERN HYBRID WARFARE AND ITS RELEVANCE FOR NATO

    Directory of Open Access Journals (Sweden)

    Sorin DUCARU

    2016-06-01

    Full Text Available The technological development and the instant communication possibilities advanced not only economic and social developments, but also evolving threats from those who exploit the vulnerabilities of communication and information systems. The cyber threat landscape points to a significant increase of the frequency, intensity, duration and sophistication of cyber-attacks. One of the new and concerning trends is the use of cyber capabilities in relation with military of hybrid operations – the so-called cyber dimension of hybrid warfare. NATO’s strategy on countering hybrid warfare is based on the triad: prepare-deter-defend, which also applies to cyber. Nations represent the first line of defence in countering hybrid strategies. International cooperation is also a key factor in this sense. It is in this context that NATO’s response to cyber-attacks in the context of hybrid warfare must be further refined.

  5. An evolutionary theory of large-scale human warfare: Group-structured cultural selection.

    Science.gov (United States)

    Zefferman, Matthew R; Mathew, Sarah

    2015-01-01

    When humans wage war, it is not unusual for battlefields to be strewn with dead warriors. These warriors typically were men in their reproductive prime who, had they not died in battle, might have gone on to father more children. Typically, they are also genetically unrelated to one another. We know of no other animal species in which reproductively capable, genetically unrelated individuals risk their lives in this manner. Because the immense private costs borne by individual warriors create benefits that are shared widely by others in their group, warfare is a stark evolutionary puzzle that is difficult to explain. Although several scholars have posited models of the evolution of human warfare, these models do not adequately explain how humans solve the problem of collective action in warfare at the evolutionarily novel scale of hundreds of genetically unrelated individuals. We propose that group-structured cultural selection explains this phenomenon. © 2015 Wiley Periodicals, Inc.

  6. Changing the Scale and Efficiency of Chemical Warfare Countermeasure Discovery Using the Zebrafish

    Science.gov (United States)

    Peterson, Randall T.; MacRae, Calum A.

    2013-01-01

    As the scope of potential chemical warfare agents grows rapidly and as the diversity of potential threat scenarios expands with non-state actors, so a need for innovative approaches to countermeasure development has emerged. In the last few years, the utility of the zebrafish as a model organism that is amenable to high-throughput screening has become apparent and this system has been applied to the unbiased discovery of chemical warfare countermeasures. This review summarizes the in vivo screening approach that has been pioneered in the countermeasure discovery arena, and highlights the successes to date as well as the potential challenges in moving the field forward. Importantly, the establishment of a zebrafish platform for countermeasure discovery would offer a rapid response system for the development of antidotes to the continuous stream of new potential chemical warfare agents. PMID:24273586

  7. Economic assessment of the contribution of biological control to the management of invasive alien plants and to the protection of ecosystem services in South Africa

    CSIR Research Space (South Africa)

    De Lange, Willem J

    2010-07-01

    Full Text Available This study is a first attempt at a holistic economic evaluation of South African endeavours to manage invasive alien plants using biological control. The author’s focus was on the delivery of ecosystem services from habitats that are invaded...

  8. Tuning the Morphology and Activity of Electrospun Polystyrene/UiO-66-NH2 Metal-Organic Framework Composites to Enhance Chemical Warfare Agent Removal.

    Science.gov (United States)

    Peterson, Gregory W; Lu, Annie X; Epps, Thomas H

    2017-09-20

    This work investigates the processing-structure-activity relationships that ultimately facilitate the enhanced performance of UiO-66-NH 2 metal-organic frameworks (MOFs) in electrospun polystyrene (PS) fibers for chemical warfare agent detoxification. Key electrospinning processing parameters including solvent type (dimethylformamide [DMF]) vs DMF/tetrahydrofuran [THF]), PS weight fraction in solution, and MOF weight fraction relative to PS were varied to optimize MOF incorporation into the fibers and ultimately improve composite performance. It was found that composites spun from pure DMF generally resulted in MOF crystal deposition on the surface of the fibers, while composites spun from DMF/THF typically led to MOF crystal deposition within the fibers. For cases in which the MOF was incorporated on the periphery of the fibers, the composites generally demonstrated better gas uptake (e.g., nitrogen, chlorine) because of enhanced access to the MOF pores. Additionally, increasing both the polymer and MOF weight percentages in the electrospun solutions resulted in larger diameter fibers, with polymer concentration having a more pronounced effect on fiber size; however, these larger fibers were generally less efficient at gas separations. Overall, exploring the electrospinning parameter space resulted in composites that outperformed previously reported materials for the detoxification of the chemical warfare agent, soman. The data and strategies herein thus provide guiding principles applicable to the design of future systems for protection and separations as well as a wide range of environmental remediation applications.

  9. Skeletal evidence for Inca warfare from the Cuzco region of Peru.

    Science.gov (United States)

    Andrushko, Valerie A; Torres, Elva C

    2011-11-01

    This article addresses the bioarchaeological evidence for Inca warfare through an analysis of 454 adult skeletons from 11 sites in the Inca capital region of Cuzco, Peru. These 11 sites span almost 1000 years (AD 600-1532), which allows for a comparison of the evidence for warfare before the Inca came to power (Middle Horizon AD 600-1000), during the time of Inca ascendency in the Late Intermediate Period (AD 1000-1400), and after the Inca came to power and expanded throughout the Cuzco region and beyond (Inca Imperial Period, AD 1400-1532). The results indicate that 100 of 454 adults (22.0%) showed evidence of cranial trauma. Of these, 23 individuals had major cranial injuries suggestive of warfare, consisting of large, complete, and/or perimortem fractures. There was scant evidence for major injuries during the Middle Horizon (2.8%, 1/36) and Late Intermediate Period (2.5%, 5/199), suggesting that warfare was not prevalent in the Cuzco region before and during the Inca rise to power. Only in the Inca Imperial Period was there a significant rise in major injuries suggestive of warfare (7.8%, 17/219). Despite the significant increase in Inca times, the evidence for major cranial injuries was only sporadically distributed at Cuzco periphery sites and was entirely absent at Cuzco core sites. These findings suggest that while the Inca used warfare as a mechanism for expansion in the Cuzco region, it was only one part of a complex expansion strategy that included economic, political, and ideological means to gain and maintain control. Copyright © 2011 Wiley-Liss, Inc.

  10. Fast and Sustained Degradation of Chemical Warfare Agent Simulants Using Flexible Self-Supported Metal-Organic Framework Filters.

    Science.gov (United States)

    Liang, Huixin; Yao, Aonan; Jiao, Xiuling; Li, Cheng; Chen, Dairong

    2018-06-20

    Self-detoxification filters against lethal chemical warfare agents (CWAs) are highly desirable for the protection of human beings and the environment. In this report, flexible self-supported filters of a series of Zr(IV)-based metal-organic frameworks (MOFs) including UiO-66, UiO-67, and UiO-66-NH 2 were successfully prepared and exhibited fast and sustained degradation of CWA simulants. A half-life as short as 2.4 min was obtained for the catalytic hydrolysis of dimethyl 4-nitrophenyl phosphate, and the percent conversion remained above 90% over a long-term exposure of 120 min, well exceeding those of the previously reported composite MOF filters and the corresponding MOF powders. The outstanding detoxification performance of the self-supported fibrous filter comes from the exceptionally high surface area, excellent pore accessibility, and hierarchical structure from the nano- to macroscale. This work demonstrates, for the first time, MOF-only filters as efficient self-detoxification media, which will offer new opportunities for the design and fabrication of functional materials for toxic chemical protection.

  11. Efikasnost sistema PVO u uslovima elektronskih dejstava / Efficiency of antiaircraft system in electronic warfare

    Directory of Open Access Journals (Sweden)

    Vladimir V. Šepec

    2007-01-01

    Full Text Available U radu je primenjena teorija masovnog opsluživanja u analizi efikasnosti sistema protivvazduhoplovne odbrane (sistema PVO u uslovima elektronskih dejstava protivnika. Prikazan je model za ocenu efikasnosti sistema PVO i predstavljeni su izrazi za procenu efikasnosti sistema PVO u uslovima elektronskih dejstava. / In this article the theory of mass servicing is used in the analysis of efficiency of antiaircraft system in the conditions of electronic warfare. The model for analysis of the antiaircraft system efficiency has been shown and formulas for qualitative analysis of antiaircraft system efficiency have been presented in the conditions of electronic warfare.

  12. Particle Swarm Social Adaptive Model for Multi-Agent Based Insurgency Warfare Simulation

    Energy Technology Data Exchange (ETDEWEB)

    Cui, Xiaohui [ORNL; Potok, Thomas E [ORNL

    2009-12-01

    To better understand insurgent activities and asymmetric warfare, a social adaptive model for modeling multiple insurgent groups attacking multiple military and civilian targets is proposed and investigated. This report presents a pilot study using the particle swarm modeling, a widely used non-linear optimal tool to model the emergence of insurgency campaign. The objective of this research is to apply the particle swarm metaphor as a model of insurgent social adaptation for the dynamically changing environment and to provide insight and understanding of insurgency warfare. Our results show that unified leadership, strategic planning, and effective communication between insurgent groups are not the necessary requirements for insurgents to efficiently attain their objective.

  13. Integrated electronic warfare framework for infrared self-protection of transport aircraft

    CSIR Research Space (South Africa)

    Annamalai, L

    2007-09-01

    Full Text Available ). With South Africa's role in the AU and NEPAD it has been widely accepted that support for UN-Sanctioned missions such as regional peacekeeping efforts, election support and the rendering of medical assistance or the supply of food to isolated areas...

  14. Protect and Defend: Adequacy of the Department of Defense Role Prescribed in the Federal Response to a Chemical or Biological Attack Against the Homeland

    Science.gov (United States)

    2002-05-31

    Maintenance Team can provide expert consultation in the areas of epidemiology and disease surveillance, medical entomology , environmental health science...the CB-RRT include, but are not limited to, the TEU, U.S. Army Edgewood Chemical and Biological Center, U.S. Army ECBC Forensic Analytical Center...medical entomology , environmental health science, toxicology, industrial hygiene, environmental sampling and analysis, health risk assessment

  15. Risk assessment of the biological plant protection product Turex 50 WG, with the organism Bacillus thuringiensis ssp. aizawai CG-91. Opinion of the Panel on Plant Protection Products of the Norwegian Scientific Committee for Food Safety

    OpenAIRE

    Källqvist, Torsten; Dirven, Hubert; Gjøen, Tor; Tronsmo, Arne; Yazdankhah, Siamak Pour; Rivedal, Edgar; Borgå, Katrine; Eklo, Ole Martin; Grung, Merete; Lyche, Jan Ludvig; Låg, Marit; Nilsen, Asbjørn Magne; Sverdrup, Line Emilie

    2016-01-01

    Bacillus thuringiensis are anaerobic, gram-positive bacteria that produce parasporal crystalline protein inclusions, δ-endotoxin, which are toxic to certain invertebrates, especially larvae belonging to the insect orders Coleoptera, Diptera and Lepidoptera. Different strains of Bacillus thuringiensis have therefore a long standing history as plant protective insecticides in many countries, but have not been approved for use in Norway. The Norwegian Scientific Committee for Food Safety (Vitens...

  16. Risk assessment of the biological plant protection products Nemasys G and Nemasys H with the active organism Heterorhabditis Bacteriophora. Opinion of the Panel on Plant Protection Products of the Norwegian Scientific Committee for Food Safety

    OpenAIRE

    Källqvist, Torsten; Borgå, Katrine; Dirven, Hubert; Eklo, Ole Martin; Grung, Merete; Lyche, Jan Ludvig; Låg, Marit; Nilsen, Asbjørn Magne; Sverdrup, Line Emilie

    2014-01-01

    Nemasys G and Nemasys H with the nematode Heterorhabditis bacteriophora as the active organism is applied for as a plant protection product in Norway. Nemasys G is intended for use against the garden chafer (Phyllopertha horticola) in lawns and Nemasys H against black vine weevil (Otiorhynchus sulcatus) in strawberries and ornamentals. VKM was requested by the Norwegian Food Safety Authority to consider the possible health and environmental risk related to the properties of Nemasys G and Nema...

  17. Chemical and biological weapons: new questions, new answers.

    Science.gov (United States)

    Hood, E

    1999-01-01

    The words "chemical and biological weapons" (CBW) send a shiver down most spines these days. With the end of the Cold War, the possibility of a massive nuclear confrontation appears remote, so today many popular doomsday scenarios center on the aggressive use of chemical or biological warfare by rogue nations or terrorist groups. As exaggerated as some of the accounts are, with CBW cast as the latest unseen, unstoppable enemy, the threat posed by these weapons is all too real, and growing. Images p931-a PMID:10585899

  18. Radiation protection; Proteccion Radiologica

    Energy Technology Data Exchange (ETDEWEB)

    Ures Pantazi, M [Universidad de la Republica, Facultad de Quimica (Uruguay)

    1994-12-31

    This work define procedures and controls about ionizing radiations. Between some definitions it found the following topics: radiation dose, risk, biological effects, international radioprotection bodies, workers exposure, accidental exposure, emergencies and radiation protection.

  19. Radiation protection standards

    International Nuclear Information System (INIS)

    Fitch, J.

    1983-11-01

    Topics covered include biological radiation effects, radiation protection principles, recommendations of the ICRP and the National Health and Medical Research Council, and dose limits for individuals, particularly the limit applied to the inhalation of radon daughters

  20. Test Operations Procedure (TOP) 10-2-022A Chemical Vapor and Aerosol System-Level Testing of Chemical/Biological Protective Suits

    Science.gov (United States)

    2013-12-16

    data, QA/quality control (QC) plans]. 3.1.2 Familiarization. a. Potential problem areas will be identified by reviewing previous records and results...also wear specified footwear , gloves, protective mask, and hood. e. Test operators will assist the TPs in obtaining correct closure of the suit at...Vernon Hills, Illinois); and Pureline II® (Dixon Industries , Charlotte, North Carolina). (4) The pressure inside each RTM while drawing air must not